van Teijlingen Edwin R
Full Text Available Abstract Background This paper describes a study protocol designed to evaluate a programme of smoking cessation interventions targeting pregnant women and young people living in urban and rural locations in Northeast Scotland. The study design was developed on so-called 'realist' evaluation principles, which are concerned with the implementation of interventions as well as their outcomes. Methods/design A two-phased study was designed based on the Theory of Change (TOC using mixed methods to assess both process and outcome factors. The study was designed with input from the relevant stakeholders. The mixed-methods approach consists of semi-structured interviews with planners, service providers, service users and non-users. These qualitative interviews will be analysed using a thematic framework approach. The quantitative element of the study will include the analysis of routinely collected data and specific project monitoring data, such as data on service engagement, service use, quit rates and changes in smoking status. Discussion The process of involving key stakeholders was conducted using logic modelling and TOC tools. Engaging stakeholders, including those responsible for funding, developing and delivering, and those intended to benefit from interventions aimed at them, in their evaluation design, are considered by many to increase the validity and rigour of the subsequent evidence generated. This study is intended to determine not only the components and processes, but also the possible effectiveness of this set of health interventions, and contribute to the evidence base about smoking cessation interventions aimed at priority groups in Scotland. It is also anticipated that this study will contribute to the ongoing debate about the role and challenges of 'realist' evaluation approaches in general, and the utility of logic modelling and TOC approaches in particular, for evaluation of complex health interventions.
Davidesko, Sharon; Segal, David; Peleg, Roni
Objective. To assess the use of cell phones and email as means of communication between pregnant women and their gynecologists and family physicians. Study Design. A cross-sectional study of pregnant women at routine followup. One hundred and twenty women participated in the study. Results. The mean age was 27.4 ± 3.4 years. One hundred nineteen women owned a cell phone and 114 (95%) had an email address. Seventy-two women (60%) had their gynecologist's cell phone number and 50 women (42%) ha...
Introduction: The aim of this study was to evaluate the frequency of bacteriuria in pregnant women referred to the medical centers of Tabriz, Iran, for prenatal care. Materials and Methods: A total of 1100 healthy pregnant women who were referred to 50 medical centers in Tabriz for a regular prenatal care were evaluated for bacteriuria. Results: The frequency of asymptomatic bacteriuria was 6.1%. Maternal age was lower in the women with a positive urine culture (P = .02). Asymptomatic bact...
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Full Text Available All the elective surgeries are to be avoided during pregnancy and pregnant women should undergo only emergency surgical interventions. Pregnancy is associated with different physiological changes in the organism, which should be taken into account in preparative preparation of the pregnant women. Expanded body fluid volume leads to dilutional anemia, however other hematological disorders may be present as well. Extreme obesity is a frequent comorbidity, while hypertension is associated with the highest risks since it may lead to a life-threatening complication - eclampsia. As for other coexisting diseases, urinary tract infections and gestational diabetes are the most common as well as hyperthyroidism and other diseases that may also develop. The type and severity of the acute surgical disease, extensiveness of the planned surgery as well as the type of planned anesthesia to be applied, occasionally necessitate, depending on the gestational age, termination of pregnancy to be considered. Gynecological-obstetric consultations are mandatory in all surgical interventions planned in pregnant women.
Full Text Available This study discusses the influence of targeted dietary modification and nutrition for pregnant women on maternal and child health. Through taking 200 pregnant women who had health files and accepted dietary guidance at Mary Maternity Hospital from March 2013 to June 2014 as the experimental group, we take 200 pregnant women who don’t accept the conventional filing of targeted dietary modification and nutrition as the control group. For the experimental group, we formulated targeted diet programs according to pregnant women’s weight and fetal growth and development so as to keep calories in a reasonable range. Compare the incidence rate of complication and delivery outcome of the two groups’ mothers and infants. The experiments show that both the incidence rate of complications and the cesarean section rate of the experimental group are lower than those of the control group and targeted dietary modification and nutrition for pregnant women has obvious positive significance on maternal and child health.
Borodulin, Katja; Evenson, Kelly R.; Monda, Keri; Wen, Fang; Amy H. Herring; Dole, Nancy
Sleep disturbances are common among pregnant women and safe treatments to improve sleep are needed. Generally, physical activity improves sleep, but studies are lacking on the associations of physical activity with sleep among pregnant women. Our aim was to investigate the cross-sectional association of various modes of physical activity and activity clusters with sleep quality and duration among 1259 pregnant women. Participants were recruited into the Pregnancy, Infection, and Nutrition Stu...
... Sumaria de los Consumidores Aug. 25, 2010 Gestational Diabetes Related Products Future Research Needs: Prioritizing Research Needs ... Women" /> Consumer Summary – Aug. 5, 2009 Gestational Diabetes: A Guide for Pregnant Women Formats Consumer Guide ( ...
Mikkelsen, A L; Schütten, G; Asping, U; Schütten, H J
Plasma concentration of atrial natriuretic peptide (ANP) was determined in pregnant women with preeclampsia, in normal pregnant and in nonpregnant women by a specific radioimmunoassay. Results did not show important differences between nonpregnant controls and normal pregnant women, but a significant rise was seen in women with preeclampsia compared to nonpregnant controls. Marked interindividual variation was found in all three groups. The mechanism of ANP release may differ between those women...
Nybo, Mads; Friis-Hansen, Lennart; Felding, Peter; Milman, Nils
The aim of the study was to investigate whether the well-known high anemia prevalence in pregnant women from the eastern Mediterranean and Asian regions decreased when the women immigrated to a low-frequency region (Denmark). During 70 months, 1,741 pregnant immigrant women referred from primary care to an obligatory hemoglobinopathy screening were eligible for the study, as their screening was negative. To compare this group with a cohort of 205 pregnant ethnic Danish women, the groups were mat...
This podcast explains why pregnant women need a flu shot. Created: 11/17/2010 by National Center for Immunization and Respiratory Diseases (NCIRD), Office of the Director (OD). Date Released: 11/17/2010.
Aponte John; Mandomando Inacio; Mabunda Samuel; Sanz Sergi; Romagosa Cleofé; Bruni Laia; Sigauque Betuel; Bardají Azucena; Sevene Esperança; Alonso Pedro L; Menéndez Clara
Abstract Background There is a widespread notion, based on limited information, that in areas of stable malaria transmission most pregnant women with Plasmodium falciparum infection are asymptomatic. This study aim to characterize the clinical presentation of malaria in African pregnant women and to evaluate the adequacy of case management based on clinical complaints. Methods A hospital-based descriptive study between August 2003 and November 2005 was conducted at the maternity clinic of a r...
Boylan, S. M.; Cade, J.E.; Kirk, S. F.; Greenwood, D.C.; White, K. L.; Shires, S; Simpson, N. A.; Wild, C. P.; Hay, A W
Studies on the effects of caffeine on health, while numerous, have produced inconsistent results. One of the most uncertain and controversial effects is on pregnancy outcome. Studies have produced conflicting results due to a number of methodological variations. The major challenge is the accurate assessment of caffeine intake. The aim of the present study was to explore different methods of assessing caffeine exposure in pregnant women. Twenty-four healthy pregnant women from the UK city of ...
To know extent of iodine deficiency (ID), role of thyroid enlargement (goiter) as marker of ID and current status of iodized salt intake in pregnant women of Lahore. A cross sectional study was carried out at Institute of Chemistry, University of the Punjab, during March 2002 to September 2005. Pregnant women (n = 254) during first trimester attending antenatal clinic participated voluntarily. Iodine intake status was determined by urinary iodine (UI) excretion. UI excretion ranged from 34 to 142 >g/L and median value was 67>g/L. According to international criteria, 202 (79.5%) pregnant women were iodine deficient (UI <100 mu g/L) mostly (68.8%) of mild (UI: 50-99 mu g/L) degree. Moderate iodine deficiency (MID; UI <50 mu g/L) was found in 63 (24.8%) pregnant women. Among all pregnant women 80 (31.5%) had slightly visible goiter and only 87(34.2%) were currently taking iodized salt. The difference in UI excretion between goitrous and non-goitrous pregnant women was not significant. Among iodized salt users percentage of women with MID was less, though not significant, as compared to non-users (20.7% Vs 26.9%). About one-fourth of pregnant women screened in this study are moderately iodine deficient in Lahore. These women and their neonates are at increased risk of iodine deficiency disorders. Goiter is not a good indicator of low iodine intake while iodized salt consumption is beneficial in this regard (JPMA 59:741; 2009). (author)
Full Text Available Background/aim: Ureaplasma urealyticum, a common commensal of the female lower genital tract, has been observed as an important opportunistic pathogen during pregnancy. The aims of this study were to determine the degree of cervical colonization with U. urealyticum in pregnant women with risk pregnancy and in pregnant women with normal term delivery and to evaluate the correlation between high-density cervical U. urealyticum colonization and premature rupture of membranes (PROM as well. Methods. This research was conducted on the samples comprising 130 hospitalized pregnant women with threatening preterm delivery and premature rupture of membranes. The control group consisted of 39 pregnant women with term delivery without PROM. In addition to standard bacteriological examination and performing direct immunofluorescence test to detect Chlamydia trachomatis, cervical swabs were also examined for the presence of U. urealyticum and Mycoplasma hominis by commercially available Mycofast Evolution 2 test (International Microbio, France. Results. The number of findings with isolated high-density U. urealyticum in the target group was 69 (53.08%, while in the control group was 14 (35.90%. Premature rupture of membranes (PROM occurred in 43 (33.08% examinees: 29 were pPROM, and 14 were PROM. The finding of U.urealyticum ?104 was determined in 25 (58.14% pregnant women with rupture, 17 were pPROM, and 8 were PROM. There was statistically significant difference in the finding of high-density U. urealyticum between the pregnant women with PROM and the control group (?² = 4.06, p < 0.05. U. urealyticum was predominant bacterial species found in 62.79% of isolates in the PROM cases, while in 32.56% it was isolated alone. Among the 49 pregnant women with preterm delivery, pPROM occurred in 29 (59.18% examinees, and in 70.83% of pregnant women with findings of high-density U. urealyticum pPROM was observed. Conclusion. Cervical colonization with U. urealyticum ? 104 is more frequent in pregnant women with risk pregnancy than in pregnant women with normal term delivery. High-density cervical U. urealyticum colonization should be observed as a possible etiological factor for PROM.
GENEVIÈVE RAIL; EMMA A. HARPER
In this article, we draw on a feminist poststructuralist perspective to explore how young pregnant women discursively construct the pregnant body in the context of the dominant obesity discourse and other prevailing bodily discourses. Open-ended interviews were conducted with 15 pregnant women between the ages of 18 and 28 coming from various socioeconomic and educational backgrounds in the Ottawa region. The poststructralist discourse analysis reveals that, overall, the participants are inte...
Willcox, M C; Liljestrand, J; Bergström, S.
In a survey of 601 pregnant women in Mozambique, 34 (5.6%) were sickle cell trait carriers. Beta thalassaemia trait did not appear to be common. There was a slight rise in Hb F values in 49 women of the type reported previously in early pregnancy.
Mikou, Sofia; Buire, Anne-Claire; Trenque, Thierry
A prospective survey is conducted in a population of pregnant women in order to evaluate the prevalence of pregnant women using over the counter medication, to define their profile and to evaluate the information received about prenatal drug exposure and teratogen risk. During the study period, 223 women were interviewed, 23.3% of them use over the counter medication. In most cases, the drugs are "comfort drug". One woman, only, had taken anti-inflammatory during the first trimester. Only 51% had received information on drug and teratogen risk. Self medication is not frequently used by the pregnant women. The information provided by health professionals, about the risk and OTC medications during pregnancy, is insufficient. PMID:19236832
Zo?nierczuk-Kieliszek, Dorota; Chemperek, Ewa; Koza, Matylda
The aim of the paper was to determine the frequency and intensity of tobacco smoking by pregnant women as well as to find out the relationship between tobacco smoking during pregnancy and socioeconomic variables (education, marital status, professional career, smoking partner, number of children) as well as health variables (severe ailments during pregnancy period, taking medicines, using medical care). The research was carried out at the department of gynecology and obstetrics of the Specialist Hospital in Jas?o as well as at the Women's Outpatient Clinic of the Public Independent Health Service Institution in Sko?yszyn (Podkarpackie Voivodship). The research was conducted by means of the questionnaire distributed from July to September 2002 among 100 pregnant women. The results of the analysis indicate that 18% of the women under survey smoked cigarettes during pregnancy, including 6% daily smokers and 12% occasional smokers. 18% of women quitted smoking when they found out that they were pregnant, and 18% of them limited smoking. Exposure to passive smoking at their family home was declared by more than a half of the pregnant women, while 14% of the surveyed women mentioned passive exposure to smoke at their workplace. The socioeconomic variables that most clearly showed positive correlation with active smoking by pregnant women were: smoking tobacco by a husband or steady partner, smoking tobacco in the presence of a pregnant woman in her workplace and at home, as well as taking advantage of a family doctor's advice. Smoking tobacco during pregnancy was also enhanced by: the lower level of education, extramarital pregnancy, permanent residence in a town or a city, poor living conditions, not working professionally during pregnancy, having two or more children, abnormal course of pregnancy, suffering from such ailments as: weepiness, problems with relaxation, lack of appetite and taking no medicines during pregnancy. PMID:16145973
Lee, S. J.; Rho, S. K.; Lee, C.H.; Chang, S. G.; Kim, J. I.
The incidence and predisposing factors of urinary calculi are generally the same in both pregnant and non pregnant women, but anatomic changes during pregnancy make diagnosis and treatment a more challenging issue. We reviewed 16 patients (22 stones) of urinary stone during pregnancy between 1986 and 1996 at Kyung Hee Medical Center. The most common symptom was flank pain, seen in 81.3% of patients, while 68.8% of patients were displayed microscopic hematuria. In all cases, diagnosis was made...
Elham Ebrahimi; Mina Soleymani; Mansoureh Jamshidimanesh; Fatemeh Hosseini
Objective: To determine the relationship between preterm birth and domestic violence against pregnant women in Iran.Materials and methods: This cross-sectional study was carried out on 600 women who were hospitalized for giving birth in one of hospitals affiliated to Tehran Medical Science University in Iran, between September 9, 2010 and December 30, 2010. This study was approved by the Research Ethics Committee affiliated with Tehran University, Iran. We applied Abuse Assessment Screen (AAS...
Rasmussen, Mikkel Mylius; Clemmensen, Dorte
Folic acid (FA) deficiency is associated with neural tube defects (NTD). In a non-risk pregnancy, The Danish National Board of Health recommends FA supplementation from planned pregnancy until three months after conception. We explored pregnant women's knowledge about and actual supplementation with FA and related this to education, number of pregnancies and age.
Full Text Available In this article, we draw on a feminist poststructuralist perspective to explore how young pregnant women discursively construct the pregnant body in the context of the dominant obesity discourse and other prevailing bodily discourses. Open-ended interviews were conducted with 15 pregnant women between the ages of 18 and 28 coming from various socioeconomic and educational backgrounds in the Ottawa region. The poststructralist discourse analysis reveals that, overall, the participants are interpellated by the dominant obesity discourse and other bodily discourses surrounding beauty, femininity, and heterosexuality. Paradoxically, they also recite alternative discourses that resist dominant bodily discourses. The young pregnant women seem to constitute themselves as conflicted subjects simultaneously reproducing dominant and subversive discourses. This leads us to conclude with a discussion surrounding the need for more realistic and inclusive subject positions within pregnancy discourses.
This podcast is targeted to pregnant women and explains 1) the signs and symptoms of the flu, and 2) what to do if you experience and signs and symptoms. This podcast is NOT a substitute for the advice of your doctor or health care provider. It is intended for educational purposes only. Created: 11/17/2010 by National Center for Immunization and Respiratory Diseases (NCIRD), Office of the Director (OD). Date Released: 11/17/2010.
H., Ben Nasr; T. S., Hammami; Z., Sahnoun; T., Rebai; M., Bouaziz; M., Kassis; K. M., Zeghal.
Full Text Available Scorpion envenomation is common in many countries; however, its effects on pregnancy are still unclear. In the present paper, we described the effects of scorpion envenomation on pregnant patients. A retrospective study was carried out considering the clinical and laboratory exams of patients admitt [...] ed to the emergency room of Habib Bourguiba Hospital, Sfax, Tunisia, from 1990 to 2004. Variability of these clinical and laboratory profiles according to maternal age, gestational age and number of previous parities was also discussed. Among 167 scorpion-envenomed women, age ranged from 17 to 42 years, 7.18% were pregnant. These presented symptoms similar to those of non-pregnant women envenomed by scorpions. Two pregnant patients developed intense pelvic pain and one manifested vaginal bleeding. Although the studied parameters showed non-significant differences, we could conclude that scorpion envenomation may lead to abnormal uterine contraction probably causing preterm delivery. Maternal disturbances induced by scorpion envenomation may influence the fetus development. The effects were more severe in the second trimester of pregnancy.
Hotelling, Barbara A
Pregnant prisoners have health-care needs that are minimally met by prison systems. Many of these mothers have high-risk pregnancies due to the economic and social problems that led them to be incarcerated: poverty, lack of education, inadequate health care, and substance abuse. Lamaze educators and doulas have the opportunity to replicate model programs that provide these women and their children with support, information, and empowering affirmation that improve parenting outcomes and decrease recidivism. PMID:19252687
Ratnam, A V; Din, S N; Hira, S. K.; Bhat, G. J.; Wacha, D S; Rukmini, A; Mulenga, R C
Because of the high incidence of congenital syphilis at the University Teaching Hospital, Lusaka, Zambia, the potential risks of congenital infection and fetal loss due to syphilis were assessed by screening 202 antenatal patients, 340 pregnant women admitted to the hospital whose pregnancies ended in either spontaneous abortion or stillbirth, and 469 consecutive babies delivered at the hospital. Primary serological screening was performed with the rapid plasma reagin test, and reactive sera ...
Hotelling, Barbara A.
Pregnant prisoners have health-care needs that are minimally met by prison systems. Many of these mothers have high-risk pregnancies due to the economic and social problems that led them to be incarcerated: poverty, lack of education, inadequate health care, and substance abuse. Lamaze educators and doulas have the opportunity to replicate model programs that provide these women and their children with support, information, and empowering affirmation that improve parenting outcomes and decrea...
Mattison, Donald; Zajicek, Anne
Because studies are often undertaken without knowledge of the pharmacokinetics of a drug, efficacy is difficult to assess in pregnant women. To address this lack, basic and clinical research within the National Institute of Child Health and Human Development is focusing on expanding knowledge of pharmacology during pregnancy. Although medication use, including prescription, over-the-counter, and herbal products, is common during pregnancy, physicians may not be aware of the nonprescription products their patients are taking or the interactions these products may have with prescribed medications. A number of studies have found sex differences in oxidative metabolism and transport, as well as pharmacologic and toxicologic differences in hepatic metabolism, that are ultimately reflected in pharmacokinetics. Sex differences exist in distribution volumes, transport proteins, and drug clearance. Beyond these sex differences, pregnancy itself affects the absorption, distribution, metabolism, and elimination of a drug. Women experience more adverse drug reactions (ADRs) than do men, and these reactions tend to be more severe. QT prolongation (torsades de pointes) and hepatic toxicity are two of the most severe ADRs, frequently causing withdrawal of a drug from the market. Women may also metabolize drugs more quickly than do men, and drugs metabolized by cytochrome P3A4 are cleared more rapidly during pregnancy. A substantial increase in the clearance of drugs eliminated by renal mechanisms also has been noted. A significant number of women are clinically depressed during pregnancy and postpartum, and eliminating treatment for depression during pregnancy may have negative consequences for both mother and fetus. Among women with depression who are treated with selective serotonin reuptake inhibitors, the dose needed to maintain efficacy increases across the course of pregnancy. Drug disposition and response not only can differ between men and women, but also between pregnant and nonpregnant women. Research is needed to understand how pregnancy alters the pharmacokinetics and pharmacodynamics of drugs; then, efficacy trials can be initiated. Alternative strategies also need to be developed to characterize safety information. PMID:17081950
Castellano-González, Maribel; Ginestre-Pérez, Messaria; Perozo-Mena, Armindo; Alaña, Freddy; Fernández-Bravo, Marisol; Rincón-Villalobos, Gresleida
To compare vaginal colonization by genital micoplasmas in pregnant and non pregnant women and to determine the association between pregnancy and colonization by these microorganisms, samples of exocervix an endocervix from pregnant (n = 80) and non pregnant (n = 65) women, from two health centers of Maracaibo, Zulia State, Venezuela were processed. The Mycoplasma-Lyo kit (bioMérieux laboratories) was used for the culture and identification of genital micoplasmas. In pregnant women, prevalences of 10% for M. hominis and 26.25% for Ureaplasma spp. were found; 35.38% for M. hominis and 20% for Ureaplasma spp. in non-pregnant, were obtained. Among the pregnant, Ureaplasma spp. was the most frequently isolated micoplasma, in symptomatic and asymptomatic; while in the non pregnant group, M. hominis was more common among the symptomatic patients; only one case (1.54%) was an asymptomatic carrier of Ureaplasma spp. The highest positivity percentages were obtained in primigravidas (48.71%) and during the second gestational trimester (34.21%). No statistically significant differences were found between vaginal colonization by genital micoplasmas according to age, number of pregnancy and gestational trimester; but they were found between the presented symptomatology and vaginal colonization by genital micoplasmas. Genital micoplasmas were isolated from gravid women at approximately the same recovery rate as in non-pregnant women; being M. hominis the most frequently isolated in non-pregnant women and Ureaplasma spp. in the pregnant group. PMID:18277432
Yilmazel, Gülay; Balci, Elçin
Background: The postpartum period is a time of transition for a pregnant woman and her new family. In this period many pregnant women are in search about the family planning methods. But contraceptive options differ depending on women’s desires such as cultural and religious believes, partner attitudes, previous contraceptive experiences.
Siziya Seter; Dusabeyezu Fidens; Masaisa Florence; Muula Adamson S; Ntaganira Joseph; Rudatsikira Emmanuel
Abstract Background Intimate partner violence (IPV), defined as actual or threatened physical, sexual, psychological, and emotional abuse by current or former partners is a global public health concern. The prevalence and determinants of intimate partner violence (IPV) against pregnant women has not been described in Rwanda. A study was conducted to identify variables associated with IPV among Rwandan pregnant women. Methods A convenient sample of 600 pregnant women attending antenatal clinic...
Laurberg, Peter; Andersen, S.; Bjarnadottir, R. I.; Carle, Allan; Hreidarsson, A. B.; Knudsen, N.; Ovesen, L.; Pedersen, Inge Bülow; Rasmussen, Lone Banke
Objective: To review methods for evaluating iodine deficiency in pregnant women and Young infants and to discuss factors to be considered in the interpretation of their results. Design: Review of the literature regarding the various methods available for assessing iodine status. Setting: Population Surveys and research studies. Subjects: Pregnant women and young infants. Results. Several factors to consider when assessing iodine status in pregnant women and young infants include: 1) the urinary ...
Nucci Luciana Bertoldi; Schmidt Maria Inês; Duncan Bruce Bartholow; Fuchs Sandra Costa; Fleck Eni Teresinha; Britto Maria Margarida Santos
INTRODUCTION: Although obesity is well recognized as a current public health problem, its prevalence and impact among pregnant women have been less investigated in Brazil. The objective of the study was to evaluate the impact of pre-obesity and obesity among pregnant women, describing its prevalence and risk factors, and their association with adverse pregnancy outcomes. METHODS: A cohort of 5,564 pregnant women, aged 20 years or more, enrolled at aproximately 20 to 28 weeks of pregnancy, see...
She?ko, V D; Lysenko, B F; Martynenko, V B; Petrushova, L D; Malik, S V; Chilishvili, A L; Dudchenko, M A
There was studied the traumatic disease course in 11 pregnant women with different variants of severe combined thoracic and abdominal trauma, constituting 1.6% of total number of injured persons, suffering polytrauma. Polytrauma have had caused severe course of traumatic disease in majority of pregnant women. In the early postshock period the complications had occurred in 90.9% of injured persons. Antenatal death of fetus was noted in 81.8% of pregnant women with polytrauma. All pregnant women after polytrauma are alive. PMID:16255193
Marnoch Gordon J
Full Text Available Abstract Background An important component of the policy to deal with the H1N1 pandemic in 2009 was to develop and implement vaccination. Since pregnant women were found to be at particular risk of severe morbidity and mortality, the World Health Organization and the European Centers for Disease Control advised vaccinating pregnant women, regardless of trimester of pregnancy. This study reports a survey of vaccination policies for pregnant women in European countries. Methods Questionnaires were sent to European competent authorities of 27 countries via the European Medicines Agency and to leaders of registries of European Surveillance of Congenital Anomalies in 21 countries. Results Replies were received for 24 out of 32 European countries of which 20 had an official pandemic vaccination policy. These 20 countries all had a policy targeting pregnant women. For two of the four countries without official pandemic vaccination policies, some vaccination of pregnant women took place. In 12 out of 20 countries the policy was to vaccinate only second and third trimester pregnant women and in 8 out of 20 countries the policy was to vaccinate pregnant women regardless of trimester of pregnancy. Seven different vaccines were used for pregnant women, of which four contained adjuvants. Few countries had mechanisms to monitor the number of vaccinations given specifically to pregnant women over time. Vaccination uptake varied. Conclusions Differences in pandemic vaccination policy and practice might relate to variation in perception of vaccine efficacy and safety, operational issues related to vaccine manufacturing and procurement, and vaccination campaign systems. Increased monitoring of pandemic influenza vaccine coverage of pregnant women is recommended to enable evaluation of the vaccine safety in pregnancy and pandemic vaccination campaign effectiveness.
Full Text Available Purpose: This descriptive study was conducted to determine the factors associated with genital hygiene behaviours in pregnant and non-pregnant women.Method and material: Seventy pregnant women and 70 non-pregnant women, aged between 25 and 45 years, who were in the third trimester of pregnancy and presented to the Gynecology and Obstetrics Clinic at the Faculty of Medicine in Konya Province, Turkey, were included in the study. The data were gathered using a questionnaire with 26 questions designed by the researcher using the Genital Hygiene Behavior Inventory (GHBI.Results: There was no significant difference between the GHBI scores of the pregnant and non-pregnant women (p>0.05. Therefore, both groups were combined, and it was aimed to discover the factors associated with genital hygiene behaviours more effectively. A positive correlation between the GHBI scores and the monthly income was found, whereas there was a negative correlation between the GHBI scores and age, marriage age, number of pregnancies, and birth (p<0.05. There was a significant difference between the GHBI scores and the educational status of the women and their husbands, the employment status of the women and the perceived income status (p<0.05. A statistically significant difference was found between the groups in terms of GHBI scores and the women’s pain and/or bleeding experience during sexual intercourse, vaginal douching, and training on the hygiene of the genital area (p<0.05.Conclusion: There was no significant difference in genital hygiene behaviours between the pregnant and non-pregnant women. This may be attributed to the fact that the genital hygiene practices of women who did not have sufficient knowledge of genital hygiene before they became pregnant did not change during pregnancy. Therefore, we suggest that midwives provide both pregnant and non-pregnant women with training on genital hygiene.
Handley, Marilyn Cooper; Avery, Daniel M
This article reviews the persistent problem of smoking, especially as it relates to the rural and underserved population. The negative effects of smoking and disparities in health that occur as a result are highlighted. The article reviews the general state of smoking in the United States and discusses health-related issues and concerns of individuals who continue to smoke. The report explores individuals' rationale for smoking, barriers to cessation, and general knowledge related to the outcomes of smoking during pregnancy. The conclusions highlight the need for providers to provide information and interventions to reduce the smoking rates of pregnant women. PMID:26333611
Full Text Available The aim of this case report is to present a rare case which has been reported with the history of small nodule like growth on mandibular buccal and lingual area. Thirty year old pregnant women reported a nodule on left mandibular buccal and lingual region. The lesion was surgically excised and sent for biopsy to differentiate from kimura?s disease, pyogenic granuloma, epithelioid angiosarcoma (EH. Histologically lesion shows proliferation of endothelial cells along blood vessels suggesting epithelioid hemangioma. The purpose of this report is to discuss and differentiate EH and other vascular rare entities occurring in the oral cavity.
Trends in Substances of Abuse among Pregnant Women and Women of Childbearing Age in Treatment Substance use ... 7.0 Alcohol and Drug Abuse Figure 1. Trends in Substances of Abuse among Pregnant Substance Abuse ...
Full Text Available Objectives: Insufficient data are available comparing medical costs, hospitalization or admission rate, and drugs used for the treatment of pregnant and non-pregnant women admited to the emergency department (ED due to suicide attempts following drug intoxication. We sought to evaluate these differences in our ED. Methods: This is a prospective, cross-sectional study; hence we attempted to follow all pregnant and non-pregnant women who were admitted in our ED at Ataturk University, Erzurum-Turkey, due to suicide attempt with drug intoxication. We have obtained records of management plans, estimated costs and hospital admission rate in the ED from 2008 to 2011 and compared in both groups. Results: A total of 309 women were registered as suicide attempts with drug intoxication. Out of these, 23 (7.4% were pregnant and 286 (92.6% were non-pregnant. The pregnant women had lower rate of past history of psychiatric illness as compared to non-pregnant women (4.3% vs. 26.2%; p=0.019. Comparison of drug intoxication revealed a higher rate of intake of organophosphate (39.1%; vs. 34.8% p<0.001 and paracetamol (39.1% vs. 19.9%; p=0.031, but a lower rate of multidrug ingestion (39.1% vs. 67.8%; p=0.005 in pregnant women. Furthermore, pregnant women have a lower rate of hospitalization in ED (56.5% vs. 77.6%, but higher rates of hospitalization in internal services (13% vs. 6.3%, and intensive care units (13% vs. 3.1%; p=0.039 compared to non-pregnant women. Consequently, the cost of therapy was also higher in pregnant (2553.5±6206.7 TL vs. 581.3±490.3 TL; p<0.001. Conclusions: Though pregnant women were admitted less frequently compared to non-pregnant women, suicide attempts with drug intoxication among pregnant women have increased consequences in terms of hospitalization rate and cost. Thus there is an urgent need to incorporate a special screening program to measure suicide risk followed by counseling for pregnant women during post-conceptual care.
Full Text Available The positive effects of partner support on pregnancy outcomes and maternal (mental health are well established in the literature. Less is known about pregnant women’s perceptions of their partner and relationship, and whether these differ from those of nonpregnant women. Therefore, in the current study, data were collected through an online questionnaire among pregnant (n = 66 and nonpregnant (n = 59 women with similar demographic profiles. The results show that pregnant women reported feeling significantly more happy with both their partner and their relationship than nonpregnant women. Importantly, we did not find any differences in self-esteem or mate value between groups. Although the present study is mainly exploratory, we suggest that pregnant women may show a positive bias in the way they view their partner and their relationship, which in turn may be beneficial to her own as well as her child’s mental and physical health.
... Vaccination Information for Women Who Are Pregnant or Breastfeeding What is smallpox vaccine? The smallpox vaccine helps ... people can take to protect themselves from smallpox. Breastfeeding Is smallpox vaccine safe for women who are ...
Lubna Makhled Al-adayleh; Hana Husni Al Nabulsi
This study aimed to identify the forms of violence against pregnant women represented in (physical violence, psychological, and social), as well as identifying the consequences of violence against pregnant women, also identifying the impact of some qualitative variables such as (level of education, housing, income level, family members). The forms of violence against a pregnant woman, and to identify the relationship between some qualitative variables and consequences of violence against preg...
Feijen-de Jong Esther I
Full Text Available Abstract Background Midwives and obstetricians are the key providers of care during pregnancy and postpartum. Information about the consultations with a general practitioner (GP during this period is generally lacking. The aim of this study is to compare consultation rates, diagnoses and GP management of pregnant women with those of non-pregnant women. Methods Data were retrieved from the Netherlands Information Network of General Practice (LINH, a nationally representative register. This register holds longitudinal data on consultations, prescriptions and the referrals of all patients listed at 84 practices in the Netherlands in 2007–2009, including 15,123 pregnant women and 102,564 non-pregnant women in the same age-range (15 to 45 years. We compared consultation rates (including all contacts with the practice, diagnoses (ICPC-1 coded, medication prescriptions (coded according to the Anatomical Therapeutic Chemical classification system, and rate and type of referrals from the start of the pregnancy until six weeks postpartum (336 days. Results Pregnant women contacted their GP on average 3.6 times, compared to 2.2 times for non-pregnant women. The most frequently recorded diagnoses for pregnant women were ‘pregnancy’ and ‘cystitis/urinary infection’, and ‘cystitis/urinary infection’ and ‘general disease not otherwise specified’ for non-pregnant women. The mean number of prescribed medications was lower in pregnant women (2.1 against 4.4. For pregnant women, the most frequent referral indication concerned obstetric care, for non-pregnant women this concerned physiotherapy. Conclusions GP consultation rates in pregnancy and postpartum shows that GPs are important providers of care for pregnant women. Therefore, the involvement of GPs in collaborative care during pregnancy and postpartum should be reinforced.
Full Text Available Abstract Background Reducing maternal and child mortality requires focused attention on better access, utilisation and coverage of good quality health services and interventions aimed at improving maternal and newborn health among target populations, in particular, pregnant women. Intervention coverage in resource and data poor settings is rarely documented. This paper describes four different methods, and their underlying assumptions, to estimate coverage of a community mobilisation women’s group intervention for maternal and newborn health among a population of pregnant women in rural Bangladesh. Methods Primary and secondary data sources were used to estimate the intervention’s coverage among pregnant women. Four methods were used: (1 direct measurement of a proxy indicator using intervention survey data; (2 direct measurement among intervention participants and modelled extrapolation based on routine longitudinal surveillance of births; (3 direct measurement among participants and modelled extrapolation based on cross-sectional measurements and national data; and (4 direct measurement among participants and modelled extrapolation based on published national data. Results The estimated women’s group intervention’s coverage among pregnant women ranged from 30% to 34%, depending on method used. Differences likely reflect differing assumptions and methodological biases of the various methods. Conclusion In the absence of complete and timely population data, choice of coverage estimation method must be based on the strengths and limitations of available methods, capacity and resources for measurement and the ultimate end user needs. Each of the methods presented and discussed here is likely to provide a useful understanding of intervention coverage at a single point in time and Methods 1 and 2 may also provide more reliable estimates of coverage trends. Footnotes 1Unpublished data from three focus group discussions with women’s group members and facilitators participating in the Women’s Groups intervention.
Rasch, V; Knudsen, L B; Wielandt, H
OBJECTIVE: To study how living conditions influence pregnancy planning and acceptance among Danish women. METHOD: A cross-sectional questionnaire study performed among 3516 pregnant women attending Odense University Hospital, Denmark. The study population consisted of women with spontaneous abortion, women with ectopic pregnancies, women attending antenatal care and women with induced abortion. They were divided into four groups: women with planned and accepted pregnancies (accepting planners, n...
Elham Rezaei; Zahra Behboodi Moghadam; Khadijeh Saraylu
Objective: Sleep disorders are common complaints of women during pregnancy. These disorders are the result of physiological, hormonal, physical changes, affecting before, during, and right after pregnancy. This study aimed to evaluate the quality of life of pregnant women with sleep disorders in the second trimester.Materials and methods: In this cross-sectional study, data was collected with continuous sampling method. A total of 100 pregnant women with sleep disturbances in their second tri...
Protein turnover was studied in nine non-pregnant (NP) women, eight pregnant (P) and two gestational diabetic (GDM) women. Whole body protein turnover, synthesis and catabolism rates were measured using a single oral dose of 15N-glycine followed by measurement of enrichment of urinary ammonia. Urinary 3-methylhistidine (3MH) excretion was measured for three consecutive days, including the day of the protein turnover study. Whole body protein turnover and synthesis rates did not differ between the P and NP women, although the synthesis rates tended to be higher in the P group. Gestational diabetic women appeared to have considerably higher rates of both turnover and synthesis. Pregnant women excreted significantly more urinary 3MH than did non-pregnant women. GDM women appeared to have lower 3MH excretion than the P women. Correlation between 3MH excretion and protein turnover rates was nearly significant (p = .06) in the NP women, but was poorly correlated (p = .43) in the P women, suggesting that muscles may be a less important site of whole body protein turnover in pregnancy than in the non-pregnant state
Näsman, P; Ortendahl, M
The purpose of the study was to test a model based on the product of value and belief, called expected utility (EU), on the addictive behaviour of smoking. A total of 40 pregnant and 40 non-pregnant women over a period of 2 weeks performed judgements on values and beliefs about consequences related to smoking for the conditions of continuing and stopping smoking. There were no differences between pregnant and non-pregnant women in the EU of smoking. Differences in expected utility between the conditions of continuing and stopping smoking were larger for health consequences compared with psychological and social consequences and consequences related to pregnancy. Expected utility gives a good description of judgements over time. Values as well as beliefs related to health consequences should be stressed in smoking cessation programmes, especially among pregnant women. PMID:17896249
Ma, Shengli; Shang, Xiaoping; Guo, Yu; Liu, Gangqiong; Yang, Jinjian; Xue, Rui
Hypertension is a common complication of pregnancy, and studies show that pregnant women are more likely to suffer from restless legs syndrome (RLS). Pregnant women with hypertension and RLS often experience disrupted sleep patterns because of activation of the nervous system. The present study aimed to clarify the relationship between hypertension and RLS in pregnant women, and their impact on sleep. We enrolled 3,781 pregnant women who were admitted at our hospital for delivery between May 2011 and May 2014. The face-to-face questionnaire used to gather data included the International RLS Study Group criteria for diagnosis, Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), and hypertension diagnosis. Depending on the time of occurrence of hypertension, it was divided into two different types: pregnancy-induced hypertension and chronic hypertension in pregnancy. Out of 3,781 patients, 453 fulfilled the diagnostic criteria for RLS and 486 met the diagnostic criteria for hypertension. Among patients with RLS, prophylactic iron supplementation was less frequently taken during pregnancy. Pregnancy-induced hypertension, rather than chronic hypertension in pregnancy, was found to be more frequent in patients with RLS; pregnant women with RLS had higher PSQI and ESS scores than pregnant controls. In our study, RLS was frequent in pregnant women, especially in those without prophylactic iron supplementation. Patients with RLS described more serious sleep disruption and excessive daytime sleepiness (EDS). In addition, pregnancy-induced hypertension was more common in patients with RLS. PMID:25647293
Full Text Available Varicella zoster virus (VZV can cause life-threatening disease in pregnant women. The aim of this study was to identify the VZV immune status in pregnant women and also determine the validity of self-reported history for chickenpox.Serologic testing for VZV was performed for 400 pregnant women attending prenatal care at clinics located in two teaching and referral hospitals in Tehran, Iran. The Enzyme Immunoassay method was used to assess IgG antibodies against VZV.A total of 400 pregnant women, aged 16-43 years (median: 27 years, mean: 27.6 ± 5.9 years, were examined in which 361 (90.3% were found to be seropositive. Sensitivity, specificity and positive and negative predictive values of patients' self reported history were 51.8%, 71.7%, 94.4% and 13.8% respectively.Serologic screening for VZV in pregnant women seems crucial. We suggest considering the pregnant women as the target group for future immunization programs in Iran.
Tuula Wallsten; Per Näsman; Bo Simonsson; Monica Ortendahl; Alf Uttermalm
Objectives: To study time estimates by women smokers for when smoking-related consequences will occur given continuing or quitting smoking. The relationship of these estimates to pregnancy and intent to quit smoking was also investigated. Methods: Over a two-week period, eighty women, selected to constitute four subgroups formed by pregnant vs. non-pregnant and trying vs. not trying to quit smoking, rated times at which they would expect smoking-related consequences to occur given continuing ...
Full Text Available Objectives: The level of dental awareness of a pregnant woman affects the sanitary condition of her own teeth and the health of the child to be born. Poor oral health is considered to be a probable risk factor for the pre-term birth or low birth weight. The aim of this work was to assess the level of oral health knowledge that determines oral health condition of pregnant women in Poland. Material and Methods: Empirical data were obtained from the National Monitoring of Oral Health and Its Determinants, financed by the Ministry of Health. This socio-epidemiological study assessed oral health status and dental health awareness, which affects that status. Study subjects included 1380 pregnant women at the age ranging from 15 to 44, randomly-selected from urban and rural environments. Dental health status was recorded in the clinical examination sheets supplied by the World Health Organization, and the socio-medical data were recorded in the questionnaire interview sheets. Results: Almost 3/4 of the pregnant women evaluated their dental health as unsatisfactory or poor. Over 60% of the pregnant women rated their knowledge and practical skills concerning care of their own teeth and of the child to be born as limited, inadequate or none. Only 40% of the pregnant women provided right answers to the questions about dental issues. Conclusions: Low oral health awareness results in poor oral health status of the study subjects. A statistical pregnant woman has a total of 13 teeth showing the symptoms of tooth decay or caries. Over 70% of the pregnant women developed gingivitis or periodontitis. There is an urgent need in Poland to make the European principle of treating pregnant women as a dentally vulnerable group obligatory.
Full Text Available Sleep problems are common complaints among pregnant women. This study was designed to compare subjective sleep problems in non-pregnancy condition, healthy and preeclamptic pregnancy as a major complication of pregnancy. We hypothesized that some sleep problems are more prevalent in females with preeclampsia.In this cross-sectional study, 102 women with preeclampsia, 106 healthy pregnant women in the third trimester and 103 healthy non-pregnant women were selected through random sampling. Age and parity were matched in the three groups. We used Global sleep assessment questionnaire (GSAQ to check the subjective sleep problems, and then we performed statistical analysis using Analysis of variance (ANOVA and Pearson Chi-square tests.Our findings revealed significant differences in initial insomnia (p = 0.034, fragmented sleep (p = 0.022, snoring (p<0.001, non-idiopathic insomnia (p = 0.045 and sadness and anxiety (p = 0.001 between the three groups. Some sleep problems were more common in preeclampctic compared to healthy pregnant women including initial insomnia, fragmented sleep, snoring, sleep apnea and non-idiopathic insomnia. Moreover, the subjects with preeclampsia revealed more fragmented sleep, snoring, sadness and anxiety and lack of getting enough sleep due to other activities compared to non-pregnant women.Different kinds of sleep problems can occur in subjects with preeclampsia in comparison with the non-pregnant and healthy pregnant subjects. Sleep problems should be evaluated during pregnancy, particularly in pregnant women with preeclampsia, and suitable treatment should be provided for any specific sleep problem.
Katariina Laine; Finn Egil Skjeldestad; Leiv Sandvik; Anne Cathrine Staff
The aim of this study was to assess the prevalence and risk factors of anal incontinence in an unselected pregnant population at second trimester. A survey of pregnant women attending a routine ultrasound examination was conducted in a university hospital in Oslo, Norway. A questionnaire consisting of 105 items concerning anal incontinence (including St. Mark's score), urinary incontinence, medication use, and comorbidity was posted to women when invited to the ultrasound examination. Results...
Helle Margrete Meltzer; Marianne Hope Abel; Margaretha Haugen; Anne Lise Brantsæter
Pregnant women and infants are exceptionally vulnerable to iodine deficiency. The aims of the present study were to estimate iodine intake, to investigate sources of iodine, to identify predictors of low or suboptimal iodine intake (defined as intakes below 100 ?g/day and 150 ?g/day) in a large population of pregnant Norwegian women and to evaluate iodine status in a sub-population. Iodine intake was calculated based on a validated Food Frequency Questionnaire in the Norwegian Mother and Chil...
Pedro Rifakis; Jesús Benitez; Gilberto Cabaniel; Elianet Araujo; Elizabeth Hernández; Magdary Colina; Blanco, Juan J.; Anna Viloria; Ymora Aguilera; Andrea Maldonado; Nestor Rubio; Gloria Gervasio; Oscar Urdaneta; Henry Perez; Marisela Ravelo
Introduction. Intestinal parasitic infections, especially due to helminths, increase anemia in pregnant women. The results of this are low pregnancy weight gain and IUGR, followed by LBW, with its associated greater risks of infection and higher perinatal mortality rates. For these reasons, in the setting of no large previous studies in Venezuela about this problem, a national multicentric study was conducted. Methods. Pregnant women from nine states were studied, a pren...
Renault, Kristina M; Nørgaard, Kirsten; Nilas, Lisbeth; Carlsen, Emma M; Cortes, Dina; Pryds, Ole; Secher, Niels J
OBJECTIVE: The objective of the study was to assess physical activity intervention assessed by a pedometer with or without dietary intervention on gestational weight gain (GWG) in obese pregnant women by comparing with a control group. STUDY DESIGN: This study was a randomized controlled trial of 425 obese pregnant women comparing 3 groups: (1) PA plus D, physical activity and dietary intervention (n = 142); (2) PA, physical activity intervention (n = 142); and (3) C, a control group receiving s...
Geysa Aguiar Romeu; Larissa Varela de Paiva; Mariana Mota Moura Fé
The purpose of this present study was to know the pharmacoepidemiological profile of pregnant women carrying HIV, the prevention actions against vertical transmission, and evaluate the service respecting the patients' level of satisfaction. It was developed a quali-quantitative longitudinal study, with the sample being composed by pregnant women carrying HIV attended at the Pharmaceutical Care Service of a public hospital of Fortaleza - state of Ceará, during the period between January and Se...
Olesen, Charlotte; Søndergaard, Charlotte; Thrane, Nana; Nielsen, Gunnar Lauge; de Jong-van den Berg, L.; Olsen, J.
Surveillance of drug safety in pregnancy often draws on administrative prescription registries. Noncompliance in the use of prescribed medication may be frequent among pregnant women owing to their fear of fetotoxic side effects. To estimate compliance in the use of prescription drugs dispensed during pregnancy, we compared prescription data from the North Jutland Prescription Database with information on drug use provided by pregnant women to the Danish National Birth Cohort (DNBC), which is a ...
Te-Fu Chan; Fan-Hao Chou; Eing-Mei Tsai; Yu-Hua Lin; Yu-Ling Lin
Background: The purpose of this study was to explore health promoting lifestyles andrelated factors in pregnant women.Methods: This was a descriptive study using convenience sampling. Altogether, 172pregnant women were recruited from a medical center in southern Taiwan.Personal data was collected, and the instruments used included perceivedhealth status, self-efficacy of health behaviors, perception of family or peers’health-promoting behaviors, and Health Promoting Lifestyle Profile (HPLP?)....
Dahl, Katja; Hvidman, Lone; Jørgensen, Finn Stener; Henriques, Carsten; Olesen, Frede; Kesmodel, Ulrik Schiøler; Kjaergaard, Hanne
OBJECTIVES: The primary aim of this study was to assess pregnant women's knowledge of first trimester combined Down's syndrome screening in a setting of required informed consent. Secondary, we wanted to identify relevant differences in knowledge level among subgroups of pregnant women, including subgroups informed in different ways about prenatal examinations. METHODS: Data stem from a population-based cross-sectional questionnaire study including 15 multiple-choice questions assessing knowledg...
Elevated plasma levels of an endogenous factor with digoxin-like immunoreactivity (DLIS) was recently found in pregnant women, and it has been postulated to play a role in the regulation of fluids and electrolytes, as well as in the pathogenesis of hypertensive disorders in pregnancy. The authors have studied the plasma levels of DLIS in normal women (before and after treatment with contraceptive pills) and in pregnant women (either normotensive or hypertensive), during the gestional and the post-partum period using a sensitive RIA method. In addition, the authors have measured the inhibition of binding activity of 3H-ouabain to intact erythrocytes in 7 plasma samples collected from healthy adults and in 5 plasma samples of women in the second or third trimester of pregnancy. In 8 normal cycling women DLIS levels were similar during the follicular phase (24.9±6.2 pg/ml d.e.) and the luteal phase (22.6±4.7 pg/ml d.e.9. Six months treatment with different preparations of contraceptive pills did not affect the concentrations of DLIS. In a cross-sectional study performed on 171 healthy pregnant women a significant increase (p3Houbain extracts of pregnant women as compared to normal adults, with a significant correlation between the data obtained with RIA and RRA method. On the other hand, no significant differences in DLIS levels were found between singleton and 9 twin pregnancies, and also between non-hypertensive and 8 hypertensive pregnant women. This data confirm that the plasma concentration of an endogenous factor (or a group of substances) with cardiac glycoside-like activity is significantly increased in pregnant women. However, further studies are necessary to well charcterize the possible role of DLIS in the pathphysiology of hypertension in pregnancy
Emília de Carvalho Coutinho
Full Text Available This study aimed to assess the care received and the barriers faced by immigrants and Portuguese pregnant women in Portugal. This is an exploratory qualitative study, resorting to applying semi-structured interviews to 60 immigrant and 22 Portuguese women. Content analysis supported by QSR Nvivo10 program was used. The study was approved by an Ethics Committee. The results showed four categories related to affective dimensions-relational, cognitive, technical-instrumental and health care policy for pregnant women. As for the barriers in health care, these were mentioned by some of the expectant mothers, especially immigrant women. Almost all, both immigrant and Portuguese, pregnant women were satisfied with the health care.
Full Text Available Background: Our understanding of pathogenesis of periodontal disease has changed remarkably over a few decades. Rather than being confined to periodontium, periodontal disease may have a wide ranging systemic effects. It is now recognized that it shares most of the common risk factors for diabetes, coronary heart disease preterm low birth weight, miscarriage or early pregnancy loss and preeclampsia. Materials and Methods: The study group comprised of 400 women (200 pregnant women and 200 non-pregnant with an age range of 18-40 years. Maternal demographic and medical data were collected. Periodontal examinations included: Oral hygiene index (OHI-S, gingival index (GI, pocket probing depth and clinical attachment loss (CAL. Results: The results were analyzed using test of proportion when OHI-S was compared in pregnant women with that of non-pregnant individuals, there was no significant difference in good oral hygiene group (P = 0.187, Z = 1.32. When the GI index was evaluated, a definite statistical difference was noted in mild, moderate and severe gingivitis (P - 0.000, Z = 0.365; P - 0.00, Z = 4.17; P - 0.000, Z = 0.75. CAL index revealed a statistical difference was observed healthy periodontium, mild, moderate and severe periodontitis in both pregnant and non-pregnant women (P = ?0.000, Z = 3.65; P - 0.000, Z = 5.83; P - 0.001, Z - 3.24; P - 0.000, Z - 6.47. Conclusion: The present study conducted supports the hypothesis that there is a definite correlation between the pregnant women and poor oral hygiene (gingivitis and periodontitis as compared with the non-pregnant controls.
Hedyeh Riazi; Saied Bashirian; Leila Amini
Objective: The purpose of this study was to determine the level of knowledge of folic acid supplementation amongst Iranian pregnant women.Materials and methods: We selected 322 women through simple randomized method in a cross section study. Data was gathered on the base of questionnaire and interview. Statistical analysis was performed using SPSS software. The value of p
Faucette, Azure N; Pawlitz, Michael D; Pei, Bo; Yao, Fayi; Chen, Kang
Children in early infancy do not mount effective antibody responses to many vaccines against commons infectious pathogens, which results in a window of increased susceptibility or severity infections. In addition, vaccine-preventable infections are among the leading causes of morbidity in pregnant women. Immunization during pregnancy can generate maternal immune protection as well as elicit the production and transfer of antibodies cross the placenta and via breastfeeding to provide early infant protection. Several successful vaccines are now recommended to all pregnant women worldwide. However, significant gaps exist in our understanding of the efficacy and safety of other vaccines and in women with conditions associated with increased susceptible to high-risk pregnancies. Public acceptance of maternal immunization remained to be improved. Broader success of maternal immunization will rely on the integration of advances in basic science in vaccine design and evaluation and carefully planned clinical trials that are inclusive to pregnant women. PMID:26366844
Hilda Razzaghi; Sarah C. Tinker
Objectives: Long-chain polyunsaturated fatty acids found in seafood are essential for optimal neurodevelopment of the fetus. However, concerns about mercury contamination of seafood and its potential harm to the developing fetus have created uncertainty about seafood consumption for pregnant women. We compared fish and shellfish consumption patterns, as well as their predictors, among pregnant and non-pregnant women of childbearing age in the US. Methods: Data from 1,260 pregnant and 5,848 no...
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Renault, Kristina M; Carlsen, Emma M; Nørgaard, Kirsten; Nilas, Lisbeth; Pryds, Ole; Secher, Niels J; Olsen, Sjurdur F; Halldorsson, Thorhallur I
BACKGROUND: Lifestyle interventions targeting obese pregnant women often result in modest reduction in gestational weight gain, pregnancy complications and related risk factors. Examining adherence to the intervention can, however, provide valuable information on the importance of the different factors targeted. OBJECTIVE: To evaluate improvements and relevance of different dietary factors targeted with respect to gestational weight gain in a 3-arm Randomised Controlled Trial (n=342) among obese...
Scheminske, Megan; Henninger, Michelle; Irving, Stephanie A.; Thompson, Mark; Williams, Jenny; Shifflett, Pat; Ball, Sarah W.; Avalos, Lyndsay Ammon; Naleway, Allison L.
Objectives: Although pregnant women are a high-priority group for seasonal influenza vaccination, vaccination rates in this population remain below target levels. Previous studies have identified sociodemographic predictors of vaccine choice, but relationships between preconception heath behaviors and seasonal influenza vaccination are poorly…
Full Text Available Objectives: Long-chain polyunsaturated fatty acids found in seafood are essential for optimal neurodevelopment of the fetus. However, concerns about mercury contamination of seafood and its potential harm to the developing fetus have created uncertainty about seafood consumption for pregnant women. We compared fish and shellfish consumption patterns, as well as their predictors, among pregnant and non-pregnant women of childbearing age in the US. Methods: Data from 1,260 pregnant and 5,848 non-pregnant women aged 16–49 years from the 1999 to 2006 National Health and Nutrition Examination Survey (NHANES were analyzed. Frequency and type of seafood consumed and adjusted associations of multiple characteristics with seafood consumption were estimated for pregnant and non-pregnant women, separately. Time trends were also examined. Results: There were no significant differences in the prevalence of fish or shellfish consumption, separately or combined, between pregnant and non-pregnant women using either the 30-day questionnaire or the Day 1, 24-h recall. Seafood consumption was associated with higher age, income, and education among pregnant and non-pregnant women, and among fish consumers these groups were more likely to consume ?3 servings in the past 30 days. Tuna and shrimp were the most frequently reported fish and shellfish, respectively, among both pregnant and non-pregnant women. We observed no significant time trends. Conclusion: There were no differences in seafood consumption between pregnant and non-pregnant women, and the factors related to seafood consumption were similar for both groups. Our data suggest that many women consume less than the recommended two servings of seafood a week.
Razzaghi, Hilda; Tinker, Sarah C.
Objectives Long-chain polyunsaturated fatty acids found in seafood are essential for optimal neurodevelopment of the fetus. However, concerns about mercury contamination of seafood and its potential harm to the developing fetus have created uncertainty about seafood consumption for pregnant women. We compared fish and shellfish consumption patterns, as well as their predictors, among pregnant and non-pregnant women of childbearing age in the US. Methods Data from 1,260 pregnant and 5,848 non-pregnant women aged 16–49 years from the 1999 to 2006 National Health and Nutrition Examination Survey (NHANES) were analyzed. Frequency and type of seafood consumed and adjusted associations of multiple characteristics with seafood consumption were estimated for pregnant and non-pregnant women, separately. Time trends were also examined. Results There were no significant differences in the prevalence of fish or shellfish consumption, separately or combined, between pregnant and non-pregnant women using either the 30-day questionnaire or the Day 1, 24-h recall. Seafood consumption was associated with higher age, income, and education among pregnant and non-pregnant women, and among fish consumers these groups were more likely to consume ?3 servings in the past 30 days. Tuna and shrimp were the most frequently reported fish and shellfish, respectively, among both pregnant and non-pregnant women. We observed no significant time trends. Conclusion There were no differences in seafood consumption between pregnant and non-pregnant women, and the factors related to seafood consumption were similar for both groups. Our data suggest that many women consume less than the recommended two servings of seafood a week. PMID:24959115
Feijen-de Jong Esther I; Baarveld Frank; Jansen Danielle EMC; Ursum Jennie; Reijneveld Sijmen A; Schellevis François G
Abstract Background Midwives and obstetricians are the key providers of care during pregnancy and postpartum. Information about the consultations with a general practitioner (GP) during this period is generally lacking. The aim of this study is to compare consultation rates, diagnoses and GP management of pregnant women with those of non-pregnant women. Methods Data were retrieved from the Netherlands Information Network of General Practice (LINH), a nationally representative register. This r...
Rodríguez-Morales, Alfonso J.; Barbella, Rosa A.; Case, Cynthia; Arria, Melissa; Ravelo, Marisela; Perez, Henry; Urdaneta, Oscar; Gervasio, Gloria; Rubio, Nestor; Maldonado, Andrea; Aguilera, Ymora; Viloria, Anna; Blanco, Juan J.; Colina, Magdary; Hernández, Elizabeth; Araujo, Elianet; Cabaniel, Gilberto; Benitez, Jesús; Rifakis, Pedro
Introduction. Intestinal parasitic infections, especially due to helminths, increase anemia in pregnant women. The results of this are low pregnancy weight gain and IUGR, followed by LBW, with its associated greater risks of infection and higher perinatal mortality rates. For these reasons, in the setting of no large previous studies in Venezuela about this problem, a national multicentric study was conducted. Methods. Pregnant women from nine states were studied, a prenatal evaluation with a coproparasitological study. Univariated and multivariated analyses were made to determine risk factors for intestinal parasitosis and related anemia. Results. During 19 months, 1038 pregnant women were included and evaluated. Intestinal parasitosis was evidenced in 73.9%: A lumbricoides 57.0%, T trichiura 36.0%, G lamblia 14.1%, E hystolitica 12.0%, N americanus 8.1%, E vermicularis 6.3%, S stercoralis 3.3%. Relative risk for anemia in those women with intestinal parasitosis was 2.56 (P < .01). Discussion. Intestinal parasitoses could be associated with conditions for development of anemia at pregnancy. These features reflect the need of routine coproparasitological study among pregnant women in rural and endemic zones for intestinal parasites. Further therapeutic and prophylactic protocols are needed. Additional research on pregnant intestinal parasitic infection impact on newborn health is also considered. PMID:17093349
Full Text Available Introduction. Intestinal parasitic infections, especially due to helminths, increase anemia in pregnant women. The results of this are low pregnancy weight gain and IUGR, followed by LBW, with its associated greater risks of infection and higher perinatal mortality rates. For these reasons, in the setting of no large previous studies in Venezuela about this problem, a national multicentric study was conducted. Methods. Pregnant women from nine states were studied, a prenatal evaluation with a coproparasitological study. Univariated and multivariated analyses were made to determine risk factors for intestinal parasitosis and related anemia. Results. During 19 months, 1038 pregnant women were included and evaluated. Intestinal parasitosis was evidenced in 73.9%: A lumbricoides 57.0%, T trichiura 36.0%, G lamblia 14.1%, E hystolitica 12.0%, N americanus 8.1%, E vermicularis 6.3%, S stercoralis 3.3%. Relative risk for anemia in those women with intestinal parasitosis was 2.56 (P<.01. Discussion. Intestinal parasitoses could be associated with conditions for development of anemia at pregnancy. These features reflect the need of routine coproparasitological study among pregnant women in rural and endemic zones for intestinal parasites. Further therapeutic and prophylactic protocols are needed. Additional research on pregnant intestinal parasitic infection impact on newborn health is also considered.
Dennis, Alicia Therese
Peripartum cardiomyopathy is a rare but important cause of maternal morbidity and mortality. Women with peripartum cardiomyopathy often present with symptoms and signs of heart failure. The diagnosis of peripartum cardiomyopathy is made after all other causes of heart failure are excluded. Emphasis is on the immediate recognition of an unwell pregnant or recently pregnant woman, early diagnosis with the use of echocardiography, and the correct treatment of heart failure. PMID:25695578
Jundt, Katharina; Haertl, Kristin; Knobbe, Angelika; Kaestner, Ralph; Friese, Klaus; Peschers, Ursula M.
Background/Aims: The aim of our study was to evaluate the prevalence of abuse among pregnant women in Germany attending our antenatal outpatient clinic and to observe whether a history of abuse had consequences for women's feelings about their pregnancy. Methods: 455 women between the 35th and 42nd weeks of gestational age were included and were asked to fill out an anonymous questionnaire concerning their pregnancy, their actual psychological state, and their history of physical/sexual abuse...
Romero, Roberto; Hassan, Sonia S; Gajer, Pawel; Tarca, Adi L; Fadrosh, Douglas W; Nikita, Lorraine; Galuppi, Marisa; Lamont, Ronald F; Chaemsaithong, Piya; Miranda, Jezid; Chaiworapongsa, Tinnakorn; Ravel, Jacques
BACKGROUND: This study was undertaken to characterize the vaginal microbiota throughout normal human pregnancy using sequence-based techniques. We compared the vaginal microbial composition of non-pregnant patients with a group of pregnant women who delivered at term. RESULTS: A retrospective case-control longitudinal study was designed and included non-pregnant women (n?=?32) and pregnant women who delivered at term (38 to 42 weeks) without complications (n?=?22). Serial samples of vaginal flui...
Z Rostamzadeh Khameneh
Full Text Available Introduction: Although the hepatitis E virus mostly causes a self-limited disease in general population, but the disease is more severe in pregnant women. Hepatitis E accounts for about 10% of pregnancy associated deaths in southern Asia. But the prevalence in Iran is almost unclear, so this study is aimed to investigate the seroprevalence of anti-HEV IgG among a population of pregnant women in West Azerbaijan of Iran. Materials and Methods: 136 pregnant women who referred to an urban health centers of Urmia for pursuing pregnancy-related health services were selected randomly and enrolled in a descriptive, cross-sectional study. Each subject was tested for the presence of anti-HEV IgG antibody using an enzyme-linked immunosorbent assay (ELISA, Dia.Pro; Diagnostic Bioprobes, Italy. Results: The mean age among 136 pregnant women was 25.12±4.91 years old (range of 14-39 years. Only five cases (3.6% among all 136 subjects were demonstrated to be seropositive for anti-HEV IgG using ELISA method. There was no significant difference between age (P=0.88, income level (P=0.19 of two seropositive and seronegative groups. All seropositive cases were from urban areas. Conclusion: The seroprevalence of anti-HEV IgG is low in the population of pregnant women in Urmia, Iran. Because of limited sample size in this study, we recommend to perform further studies with larger sample size in other regions of Iran in order to be able to systematically generalize the findings of studies to the population of Iranian pregnant women. Keywords: Pregnancy, Hepatitis E, women ELISA
Bullock, Linda; Bloom, Tina; Davis, Jan; Kilburn, Erin; Curry, Mary Ann
Disclosure of abuse by pregnant women can vary depending on whether the woman is assessed directly by a trained interviewer versus written questionnaires, and if she is asked repeatedly during the course of pregnancy. One thousand pregnant women were enrolled in a randomized clinical trial designed to assess the effects of a nursing case management intervention on the mental and physical well-being of pregnant women experiencing or at risk for abuse. Thirteen percent of the total study participants reported current abuse and/or abuse within the past year, with only 2% of those reporting that the abuse occurred during pregnancy. The incidence of reported abuse was much higher among Medicaid-funded women (28.9%) than privately insured women (8.7%). Regardless of source of payment, women reporting abuse were significantly younger, less educated, nonwhite with lower income, and had significantly higher stress and lower self-esteem than women not reporting abuse. A high incidence of women reporting intimate partner violence described being choked on the Danger Assessment Screen (34%). We strongly urge that choking be added to routine screening questions used during pregnancy and that the Danger Assessment tool is used for further evaluation of women who screen positive. In addition, we believe another barrier to reporting abuse was fear of being reported to child protective services, contributing to the overall low rate of abuse disclosure. PMID:16945784
Objective: To assess the serum level of vitamin D in pregnant and lactating women. Study Design: Case-control study. Place and Duration of Study: Gynaecological Unit 1 of Jinnah Hospital, Lahore, from December 2010 to May 2011. Methodology: A total of 100 women comprised of three groups: pregnant (n = 40), lactating (n = 40) and control (n = 20) groups. The information regarding age, educational level, socioeconomic status, exposure to sunlight and dietary vitamin D intake were collected through self-structured questionnaire. Serum concentration of vitamin D was measured by ELISA and serum calcium and phosphate levels were measured by chemistry analyzer. Statistical analysis was done using SPSS (version 13). The values were considered significant at 0.05 level of significance. Results: The mean serum vitamin D level in the pregnant and lactating mothers was 26.5 +- 17.1 nmol/L and 21.4 +- 16.3 nmol/L respectively and in control group was 33.8 +- 21.1 nmol/L. The mean calcium level in the pregnant, lactating and control group was 10.3 +- 1.2 mg/dL, 9.7 +- 1.3 mg/dL and 9.7 +- 1.3 mg/dL respectively. The mean phosphate in pregnant was 3.2 +- 0.76 mg/dl, in lactating was 3.3 +- 0.76 mg/dl and in control was 3.5 +- 0.92 mg/dl. Significant difference (p = 0.041 and p = 0.037 respectively) in the serum levels of vitamin D and calcium was observed among the pregnant and lactating women as compared to control group. Conclusion: Low serum vitamin D concentration was observed in lactating women and pregnant women as compared to control group. (author)
Because alterations in natural killer (NK) activity in the perinatal period may be important in the maintenance of a healthy pregnancy, the mechanisms by which these alterations are mediated in neonates and in pregnant and postpartum women was examined. NK activity, as measured in a 4-hr 51Cr-release assay and compared with adult controls, is significantly diminished in all three trimesters of pregnancy and in immediately postpartum women. In postpartum women, NK activity appears to be higher than in pregnant women, although this does not reach statistical significance. Pregnant and postpartum women have normal numbers of large granular lymphocytes and normal target cell binding in an agarose single cell assay but decreased lysis of the bound target cells. NK activity of mononuclear cells from postpartum women, in addition, demonstrate a shift in distribution to higher levels of resistance to gamma-irradiation. Further, sera from postpartum women cause a similar shift to increased radioresistance in mononuclear cells from adult controls. Because radioresistance is a property of interleukin 2-stimulated NK, the shift to radioresistance may represent lymphokine-mediated stimulation occurring during parturition. In contrast, cord blood cells have a more profound decrease in NK activity as determined by 51Cr-release assay and decreases in both binding and lysis of bound target cells in the single cell assay. The resistance of NK activity in cord cells to gamma-irradiation is also increased, as seen in postpartum women. Cord blood serum, however, did not alter radioresistance or inhibit NK activity. The results suggest that the observed diminished NK activity in pregnant women and neonates arise by different mechanisms: an absence of mature NK cells in the neonate and an alteration of the NK cell in pregnancy leading to decreased killing
Bogaerts, Annick; Devlieger, Roland; Nuyts, Erik; Witters, Ingrid; Gyselaers, Wilfried; Van den Bergh, Bea
OBJECTIVE: Lifestyle intervention could help obese pregnant women to limit their weight gain during pregnancy and improve their psychological comfort, but has not yet been evaluated in randomized controlled trials. We evaluated whether a targeted antenatal lifestyle intervention programme for obese pregnant women influences gestational weight gain (GWG) and levels of anxiety or depressed mood. DESIGN AND SUBJECTS: This study used a longitudinal interventional design. Of the 235 eligi...
Table 2.4 presents summary data from several epidemiologic surveys collecting food and supplement intake data from pregnant or lactating women. More details on the specific surveys are included in Table 2.5. The two most recent US nutrition monitoring surveys, the 1999-2000 National Health and Nutrition Examination Survey (NHANES) and the 1994-96 Continuing Survey of Food Intake of Individuals (CSFII), each included 24HR (24-Hour Recall) interviews to assess diet and supplement intake. Neither survey included a sizable number of pregnant or lactating women.
Hamissi, J; Bakianian Vaziri, P.; A Davalloo
"nBackground: The purpose of this study was to describe the knowledge and attitude of pregnant women in Qazvin Province, central Iran, Relating to oral Hygiene."nMethods: The study group comprised of 760 pregnant women living in Qazvin, center of Iran in 2004. The questions were formulated to evaluate information without the need for dental examination. The age groups between 17-41 years old were randomly selected and a question was given to woman in three family planning center. St...
Full Text Available Anemia is the most common nutritional deficiency disorder in the world. WHO has estimated the prevalence of anemia in pregnant women in developed and developing countries, and that is 14% in developed and 51% in developing countries.1 Anaemia in pregnancy remains one of the most intractable public health problems in the developing countries.2,3 The World Health Organization (WHO has estimated that more than half of the pregnant women in the world have a haemoglobin level (<11.0 g/dl which is indicative of anaemia.
Because of the rapid proliferation of the use of video display units for data processing, we have investigated the levels of the personnel exposure to parasit X-rays emission from these devices. The case of pregnant women was investigated because the greater part of the staff involved is female. In the worst case, the dose equivalent received by the foetus at the most exposed point is estimated at 0,01 ?Sv. This level is too low to cause any pathology. There is, therefore, no reason to discard pregnant women from the use of video display units
Rosenbloom, Laura; Buchert, Elizabeth; Vasiloff, Rosanne; Feinglass, Joseph; Dong, Xinqi; Simon, Melissa
The purpose of this study is to develop an intervention to help women meet weight gain goals during pregnancy. From 2007 to 2008, pregnant women were recruited at a clinic in Chicago. Intervention participants received an educational pamphlet at their first prenatal visit. At follow up visits, provider counseling was encouraged via a weight gain trend graph and targeted feedback checklist. The primary outcome was the total weight gained over the course of prenatal care. We analyzed 57 intervention group participants and 109 controls. Demographic composition was similar between the groups except for parity. Patients in the intervention group and routine care group gained similar weight (24.5 + 13.5 lb vs. 25.3 + 14.0 lb, P = 0.71). After controlling for baseline weight, the intervention was associated with 4.6 pounds lower follow-up weight (P = 0.029). After controlling for baseline BMI and other covariates, participants who received the intervention were only 34% as likely to gain weight exceeding IOM guidelines (P = 0.009). This pilot prenatal care obesity prevention project was associated with lower weight gain in pregnancy. The feedback checklist, weight gain graph, and educational pamphlet on weight gain proved to be favorable components of this project and merit further examination in a larger intervention trial. PMID:22227775
Full Text Available Objectives: To study time estimates by women smokers for when smoking-related consequences will occur given continuing or quitting smoking. The relationship of these estimates to pregnancy and intent to quit smoking was also investigated. Methods: Over a two-week period, eighty women, selected to constitute four subgroups formed by pregnant vs. non-pregnant and trying vs. not trying to quit smoking, rated times at which they would expect smoking-related consequences to occur given continuing or quitting smoking. Results: Somatic health consequences were estimated to occur later than consequences related to mood and social relations. All consequences were estimated to occur later given quitting smoking. Pregnancy had an effect on the estimated time that consequences would occur, with pregnant women estimating earlier occurrence of consequences related to mood and social relations than non-pregnant women did. Conclusion: Health messages should stress consequences for somatic health in quitting smoking, since outcomes later in time might have too low a value to exert a positive effect on decisions to quit smoking.
Nana Philip N
Full Text Available Abstract Objective To compare the prevalence of gynaecological conditions among HIV infected and non-infected pregnant women. Methods Two thousand and eight (2008 pregnant women were screened for HIV, lower genital tract infections and lower genital tract neoplasia at booking antenatal visit. Results About 10% (198/2008 were HIV positive. All lower genital tract infections except candidiasis were more prevalent among HIV positive compared to HIV negative women: vaginal candidiasis (36.9% vs 35.4%; p = 0.678, Trichomoniasis (21.2% vs 10.6%; p p p = 0.026, syphilis (35.9% vs 10.6%; p Chlamydia trachomatis (38.4% vs 7.1%; p p p Conclusion We conclude that (i sexually transmitted infections (STIs are common in both HIV positive and HIV negative pregnant women in Cameroon, and (ii STIs and preinvasive cervical lesions are more prevalent in HIV-infected pregnant women compared to their non-infected compatriots. We recommend routine screening and treatment of STIs during antenatal care in Cameroon and other countries with similar social profiles.
Blood concentration profiles for follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, testosterone, estradiol, estriol, progesterone, cortisol and sex hormonebinding globulin throughout a menstrual cycle were derived from measurements by radioimmunoassay and related procedures on serial blood samples from 16 normal women as controls. Similar studies were then performed on 9 normal women receiving a low-dose oral contraceptive combination of D-norgestrel and ethynlestradiol. Further studies were performed on 9 out of 16 normal women in whom progestational contraception was carried out with orally administered lynestrenol or intramuscularly administered norethindrone enathate and on 12 normal pregnant women from the 28th to the 38th week of pregnancy. Additional studies embracing chorionic gonadotropin progesterone and 17-hydroxyprogesterone were performed on 10 normal pregnant women from the 6th to the 12th week of pregnancy. Detailed results are presented and their significance discussed
Anna L. Njunda
Full Text Available Toxoplasmosis is caused by an intracellular protozoan, Toxoplasma gondii, which has a wide geographical distribution. The congenital form results in a gestational form that can present a temporary parasiteamia that will infect the fetus. For this reason early diagnosis in pregnancy is highly desirable, allowing prompt intervention in cases of infection. The aim of this study was to determine the seroprevalence of Toxoplasma gondii antibodies among pregnant women attending the Douala General Hospital. The study was carried out between March and July 2009, whereby 110 pregnant women were tested for IgG and IgM antibodies and information about eating habits and hygienic conditions was collected using a questionnaire. These women’s ages ranged from 20-44 years old with an average of 29.9 years; the overall IgG and IgM seroprevalence was 70% and 2.73 % respectively. Seroprevalence was significantly high amongst women who ate raw vegetables (76.39%, P<0.05 and there was a significant trend towards a higher seroprevalence in women who did not have a good source of water (75.58%, P<0.05. This research showed that consumption raw vegetables and poor quality drinking water are two risk factors associated with Toxoplasma gondii infection amongst pregnant women attending the Douala General Hospital in Cameroon.
Petersen, Kathrine Birch; Johansen, Helle Krogh; Rosthoj, Susanne; Krebs, Lone; Pinborg, Anja; Hedegaard, Morten
INTRODUCTION: Group B streptococci (GBS) can cause preterm delivery for women and sepsis and meningitis in infants younger than 90 days of age. The present retrospective cohort study determines the trend over time in the rates of GBS and in demographic risk factors for GBS among pregnant women delivering at Rigshospitalet (RH). MATERIAL AND METHODS: In the period from 2002 to 2010, a total of 33,616 women gave birth at the RH. Our cohort was defined as 16,587 (49%) women examined by 24,724 cultu...
Andersen, Stine Linding
Iodine is required for the synthesis of thyroid hormones, which are crucial regulators of early brain development. The source of iodine in the fetus and the breastfed infant is maternal iodine, and adequate iodine intake in pregnant and breastfeeding is of major concern. Severe iodine deficiency can cause irreversible brain damage, whereas the consequences of mild to moderate iodine deficiency are less clear. Denmark was previously iodine deficient with regional differences and a mandatory iodin...
Andersen, Stine Linding
Iodine is required for the synthesis of thyroid hormones, which are crucial regulator of early brain development. The source of iodine in the fetus and the breastfed infant is maternal iodine, and adequate iodine intake in pregnant and breastfeeding is of major concern. Severe iodine deficiency can cause irreversible brain damage, whereas the consequences of mild to moderate iodine deficiency are less clear. Denmark was previously iodine deficient with regional differences (mild iodine deficienc...
Full Text Available Abstract Background Overweight and obesity during pregnancy raise the risk of gestational diabetes and birth complications. Lifestyle factors like physical activity may decrease these risks through beneficial effects on glucose homeostasis. Here we examined physical activity patterns and their relationships with measures of glucose homeostasis in late pregnancy compared to non-pregnant women. Methods Normal weight and overweight women without diabetes (N = 108; aged 25-35 years were studied; 35 were pregnant (in gestational weeks 28-32 and 73 were non-pregnant. Insulin sensitivity and ?-cell response were estimated from an oral glucose tolerance test. Physical activity was measured during 10-days of free-living using a combined heart rate sensor and accelerometer. Total (TEE, resting (REE, and physical activity (PAEE energy expenditure were measured using doubly-labeled water and expired gas indirect calorimetry. Results Total activity was associated with reduced first-phase insulin response in both pregnant (Regression r2 = 0.11; Spearman r = -0.47; p = 0.007 and non-pregnant women (Regression r2 = 0.11 Spearman; r = -0.36; p = 0.002. Relative to non-pregnant women, pregnant women were estimated to have secreted 67% more insulin and had 10% lower fasting glucose than non-pregnant women. Pregnant women spent 13% more time sedentary, 71% less time in moderate-to-vigorous intensity activity, had 44% lower objectively measured total activity, and 12% lower PAEE than non-pregnant women. Correlations did not differ significantly for any comparison between physical activity subcomponents and measures of insulin sensitivity or secretion. Conclusions Our findings suggest that physical activity conveys similar benefits on glucose homeostasis in pregnant and non-pregnant women, despite differences in subcomponents of physical activity.
Munro, Kimberly; Jarvis, Catherine; Munoz, Marie; D'Souza, Vinita; Graves, Lisa
The present literature review was conducted to determine what information has been published on the topic of undocumented pregnant migrants. Scientific databases and gray literature sources were searched for articles published between January 1967 and September 2010. Eighty-seven articles met the inclusion criteria and were reviewed. A final sample of 23 articles was included in the review. Existing evidence suggests that pregnant undocumented migrants living in Western societies tend to be younger, unmarried, and more likely to be employed in the domestic sector than documented migrants and permanent residents. They have less access to prenatal care and consult later in pregnancy than controls. Findings concerning delivery and birth outcomes are conflicting and subject to several biases. Little has been published on programs to address the needs of undocumented pregnant women living in Western countries. More research on the particular health and social issues faced by these women is needed. PMID:22382439
Full Text Available Background: Listeriosis is a food-borne disease often associated with ready-to-eat foods. It usually causes mild febrile gastrointestinal illness in immunocompetent persons. In pregnant women, it may cause more severe infection and often crosses the placenta to infect the fetus, resulting in miscarriage, fetal death or neonatal morbidity. Simple precautions during pregnancy can prevent listeriosis. However, many women are unaware of these precautions and listeriosis education is often omitted from prenatal care.
Krohn, M A; Hillier, S. L.; Eschenbach, D A
The diagnosis of bacterial vaginosis is usually based on clinical criteria including homogeneous vaginal discharge, an elevated vaginal pH, the presence of clue cells, and an amine odor. We have evaluated the vaginal flora and clinical signs for 593 pregnant women. Gardnerella vaginalis, Bacteroides spp., and Mycoplasma hominis were isolated more frequently among women with clinical signs than among those without clinical signs of bacterial vaginosis in multivariable analyses that controlled ...
Ramos, Nubia L.; Sekikubo, Musa; Dzung, Dang Thi Ngoc; Kosnopfel, Corinna; Kironde, Fred; Mirembe, Florence; Brauner, Annelie
Urinary tract infection (UTI) is common during pregnancy and can be associated with negative outcomes for both the mother and fetus. Increased risk of infection among these patients has been attributed to physiological changes, and less focus has been placed on Escherichia coli, the most frequent causative agent. We investigated the virulence properties of isolates causing UTI in pregnant women in Sweden, Uganda, and Vietnam, as well as nonpregnant women in Sweden. Although phylogenetic group...
Full Text Available Background: Nutritional anaemia in pregnant women is one of the India’s major public health problems, despite the fact that this problem is largely preventable & easily treatable. Objectives: 1.To determine the prevalence of anaemia in pregnant women. 2. To assess the epidemiological determinants of anaemia in pregnancy. Methodology: A descriptive case series study was conducted among the pregnant women from second trimester onwards from urban field practice area from 1st March 2010 to 31st July 2010 by using pre-designed, pre-tested, structured schedule. Haemoglobin estimation was done by Sahli’s method & anaemia was graded according to WHO criteria. Statistical analyses were done by percentages and proportions, Mean and Standard Deviation (S.D, Chi-square test. Results: A high prevalence (82.9% of anaemia (Haemoglobin - < 11.0gm/dl was observed among 228 pregnant women. Majority (50.4% had moderate degree of anaemia (Haemoglobin - 7.0 to 10.0 gm/dl and 7.0% had severe anaemia (Haemoglobin - < 7.0 gm/dl. Severity of anaemia was more in 26 years of age, from nuclear families, educated upto secondary level, having vegetarian diet, parity two or more & those in third trimester with two or more abortions, although statistically not significant. However, anaemia prevalence was significantly higher among those subjects from below Class IV socio-economic status, those with less than two years of spacing between previous and index pregnancies & with less than two months IFA tablet consumption. Conclusion: A very high prevalence of anaemia in pregnancy needs mandatory regular supply of IFA tablets to adolescent and pregnant women from 4th month onwards till 3-6 months post-partum along with correction of other nutritional deficiencies and timely intervention for reducing the burden of related diseases.
Full Text Available Background: Toxoplasma gondii is an obligate intracellular protozoan parasite which can infect human and animals. Acquired toxoplasmosis during pregnancy can lead to fetal infection, which may ultimately result in loss of fetus or lesion in brain and eyes. This study was performed to evaluate the seroepidemiological status of toxoplasmosis in pregnant women in Ilam City, western Iran. Methods: In this cross-sectional study, 553 blood samples were collected from pregnant women. Sera were separated by blood centrifugation at 3000 rpm for 5 min and frozen at -20 °C until use. The samples were tested for IgG antibody by Indirect Immunoflourecence antibody test (IFA. Results: Out of the 553 pregnant women, 247 were positive for T. gondii IgG antibodies and 306 were negative. The mean age of women was 21 and the seropositive rate of latent T. gondii infection was 44.8%. Conclusion: About half of the married women in the present study were at risk of infection with T.gondii, so preventive method should be considered. Keywords: Seroepidemiology, Toxoplasmosis, IFA, Iran.
Andersen, Stine Linding
Iodine is required for the synthesis of thyroid hormones, which are crucial regulator of early brain development. The source of iodine in the fetus and the breastfed infant is maternal iodine, and adequate iodine intake in pregnant and breastfeeding is of major concern. Severe iodine deficiency can cause irreversible brain damage, whereas the consequences of mild to moderate iodine deficiency are less clear. Denmark was previously iodine deficient with regional differences (mild iodine deficiency in East Denmark and moderate iodine deficiency in West Denmark), and also pregnant and breastfeeding women suffered from iodine deficiency. A mandatory iodine fortification of household salt and salt used for commercial production of bread was introduced in Denmark in the year 2000. The PhD thesis investigates intake of iodine supplements and urinary iodine status in Danish pregnant and breastfeeding women after the introduction of the mandatory iodine fortification of salt in a region of Denmark with previously moderate iodine deficiency. Additionally, the PhD thesis addresses mechanisms of iodide transport to the fetus across the placenta and methodological challenges in the evaluation of urinary iodine status in pregnant and breastfeeding women.
Full Text Available UTI is one of the most common medical complications of pregnancy together with anemia and hypertension and it occurs approximately in 5-10% of all pregnancies. The aim of this study was to determine the distribution of uropathogens isolated from pregnant women. During the study period, 255 pregnant women urine samples were analysed. Urinary tract infection was diagnosed by growth of at least 105 colony-forming units of a urinary tract pathogen per milliliter in a culture of a midstream urine sample. After 24-48 h incubation organisms verified by biochemical tests. The results show that the 10.58% of pregnant women have UTI and most agent of UTI in these group was E. coli. UTIs may be more serious during pregnancy because they are more likely to travel to the kidneys. If a UTI is not treated promptly in a pregnant woman, she may be more likely to have problems like high blood pressure or premature delivery of her baby.
Nucci Luciana Bertoldi
Full Text Available INTRODUCTION: Although obesity is well recognized as a current public health problem, its prevalence and impact among pregnant women have been less investigated in Brazil. The objective of the study was to evaluate the impact of pre-obesity and obesity among pregnant women, describing its prevalence and risk factors, and their association with adverse pregnancy outcomes. METHODS: A cohort of 5,564 pregnant women, aged 20 years or more, enrolled at aproximately 20 to 28 weeks of pregnancy, seen in prenatal public clinics of six state capitals in Brazil were followed up, between 1991 and 1995. Prepregnancy weight, age, educational level and parity were obtained from a standard questionnaire. Height was measured in duplicate and the interviewer assigned the skin color. Nutritional status was defined using body mass index (BMI, according to World Health Organization (WHO criteria. Odds ratios and 95% confidence interval were calculated using logistic regression. RESULTS: Age-adjusted prevalences (and 95% CI based on prepregnancy weight were: underweight 5.7% (5.1%-6.3%, overweight 19.2% (18.1%-20.3%, and obesity 5.5% (4.9%-6.2%. Obesity was more frequently observed in older black women, with a lower educational level and multiparous. Obese women had higher frequencies of gestational diabetes, macrosomia, hypertensive disorders, and lower risk of microsomia. CONCLUSIONS: Overweight nutritional status (obesity and pre-obesity was seen in 25% of adult pregnant women and it was associated with increased risk for several adverse pregnancy outcomes, such as gestational diabetes and pre-eclampsia.
Full Text Available Abstract Background Intimate partner violence (IPV, defined as actual or threatened physical, sexual, psychological, and emotional abuse by current or former partners is a global public health concern. The prevalence and determinants of intimate partner violence (IPV against pregnant women has not been described in Rwanda. A study was conducted to identify variables associated with IPV among Rwandan pregnant women. Methods A convenient sample of 600 pregnant women attending antenatal clinics were administered a questionnaire which included items on demographics, HIV status, IPV, and alcohol use by the male partner. Mean age and proportions of IPV in different groups were assessed. Odds of IPV were estimated using logistic regression analysis. Results Of the 600 respondents, 35.1% reported IPV in the last 12 months. HIV+ pregnant women had higher rates of all forms of IVP violence than HIV- pregnant women: pulling hair (44.3% vs. 20.3%, slapping (32.0% vs. 15.3%, kicking with fists (36.3% vs. 19.7%, throwing to the ground and kicking with feet (23.3% vs. 12.7%, and burning with hot liquid (4.1% vs. 3.5%. HIV positive participants were more than twice likely to report physical IPV than those who were HIV negative (OR = 2.38; 95% CI [1.59, 3.57]. Other factors positively associated with physical IPV included sexual abuse before the age of 14 years (OR = 2.69; 95% CI [1.69, 4.29], having an alcohol drinking male partner (OR = 4.10; 95% CI [2.48, 6.77] for occasional drinkers and OR = 3.37; 95% CI [2.05, 5.54] for heavy drinkers, and having a male partner with other sexual partners (OR = 1.53; 95% CI [1.15, 2.20]. Education was negatively associated with lifetime IPV. Conclusion We have reported on prevalence of IPV violence among pregnant women attending antenatal care in Rwanda, Central Africa. We advocate that screening for IPV be an integral part of HIV and AIDS care, as well as routine antenatal care. Services for battered women should also be made available.
Environmental phenols are a group of chemicals with widespread uses in consumer and personal care products, food and beverage processing, and in pesticides. We assessed exposure to benzophenone-3, bisphenol A (BPA), triclosan, methyl- and propyl parabens, and 2,4- and 2,5-dichlorophenol or their precursors in 506 pregnant women enrolled in the National Children's Study (NCS) Vanguard Study. We measured the urinary concentrations of the target phenols by using online solid-phase extraction–isotope dilution high performance liquid chromatography–tandem mass spectrometry. NCS women results were compared to those of 524 similar-aged women in the National Health and Nutrition Examination Survey (NHANES) 2009–2010, and to 174 pregnant women in NHANES 2005–2010. In the NCS women, we found significant racial/ethnic differences (p<0.05) in regression adjusted mean concentrations of benzophenone-3, triclosan, 2,4- and 2,5-dichlorophenol, but not of BPA. Urinary 2,4- and 2,5-dichlorophenol concentrations were highly correlated (r=0.66, p<0.0001). Except for BPA and triclosan, adjusted mean concentrations were significantly different across the 7 study sites. Education was marginally significant for benzophenone-3, triclosan, propyl paraben, and 2,5-dichlorophenol. Urinary concentrations of target phenols in NCS pregnant women and U.S. women and pregnant women were similar. In NCS pregnant women, race/ethnicity and geographic location determined urinary concentrations of most phenols (except BPA), suggesting differential exposures. NCS Main Study protocols should collect urine biospecimens and information about exposures to environmental phenols. - Highlights: • Limited biomonitoring data are available in pregnant women. • Seven urinary phenols were measured in 506 third trimester women enrolled in the NCS. • Urine benzophenone-3, triclosan, 2,4- and 2,5-dichlorophenol differed by race/ethnicity. • Urinary concentrations of 2,4- and 2,5-dichlorophenol were highly correlated. • Exposure information can expand the utility of biospecimens in the NCS Main Study
Cystitis is a bacterial infection of the lower urinary tract which causes pain when passing urine, and causes frequency, urgency, haematuria, and suprapubic pain not associated with passing urine. Recurrent cystitis is usually defined as three episodes of UTI in the previous 12 months, or two episodes in the previous 6 months.It is common in young, healthy women, with one study finding 27% of women developing a second infection within 6 months of the first, and 2.7% having a second recurre...
Romero, Roberto; Hassan, Sonia S
BACKGROUND: This study was undertaken to characterize the vaginal microbiota throughout normal human pregnancy using sequence-based techniques. We compared the vaginal microbial composition of non-pregnant patients with a group of pregnant women who delivered at term. RESULTS: A retrospective case-control longitudinal study was designed and included non-pregnant women (n?=?32) and pregnant women who delivered at term (38 to 42 weeks) without complications (n?=?22). Serial samples of vaginal fluid were collected from both non-pregnant and pregnant patients. A 16S rRNA gene sequence-based survey was conducted using pyrosequencing to characterize the structure and stability of the vaginal microbiota. Linear mixed effects models and generalized estimating equations were used to identify the phylotypes whose relative abundance was different between the two study groups. The vaginal microbiota of normal pregnant women was different from that of non-pregnant women (higher abundance of Lactobacillus vaginalis, L. crispatus, L. gasseri and L. jensenii and lower abundance of 22 other phylotypes in pregnant women). Bacterial community state type (CST) IV-B or CST IV-A characterized by high relative abundance of species of genus Atopobium as well as the presence of Prevotella, Sneathia, Gardnerella, Ruminococcaceae, Parvimonas, Mobiluncus and other taxa previously shown to be associated with bacterial vaginosis were less frequent in normal pregnancy. The stability of the vaginal microbiota of pregnant women was higher than that of non-pregnant women; however, during normal pregnancy, bacterial communities shift almost exclusively from one CST dominated by Lactobacillus spp. to another CST dominated by Lactobacillus spp. CONCLUSION: We report the first longitudinal study of the vaginal microbiota in normal pregnancy. Differences in the composition and stability of the microbial community between pregnant and non-pregnant women were observed. Lactobacillus spp. were the predominant members of the microbial community in normal pregnancy. These results can serve as the basis to study the relationship between the vaginal microbiome and adverse pregnancy outcomes.
Full Text Available Backround: Worldwide, approximately 1 billion people, from which 200-250 million are women, smoke. Based on the Estonian Medical Birth Register data, in 2010, 7,5% of pregnant women were smokers, and in 2012, 7% of pregnant women were smoking during their pregnancy. Thus, smoking rates among pregnant women fell only 0,5%. The objective of the research was to find out the views of pregnant women who were smoking during pregnancy of the effect of smoking on the health of them and their babies, and experiences in quitting smoking, changing indicators, e.g. smoking and socioeconomical status (initial exposure to smoking, employment, long-term partnerships etc. in 2009-2013.Methods: This research is a phenomenological study, which was being carried out from October 2009 until January 2013. Data collection methods were semi-structured interviews with 45 pregnant women smoking during their pregnancy and being registered for antenatal care in three health care institutions of Republic of Estonia. An inductive approach for qualitative analysis was used.Results: Most women smoking during pregnancy started smoking in their teens, their parents smoked, they were under 30 years old housewives or unemployed. On an average of 11-20 cigarettes were consumed each day, the pregnancy of the research group did not influence frequency and tobacco intake. The participants in the research group reported that tobacco consumption helped them relax, gave them a chance to spend time in a good company, and it was not regarded as a bad habit but a social addiction, being caused by availability of tobacco products. Although most of them had an opinion about harmful effects of smoking, e.g. a cough, asthma and rapid fatigue, on the health of them and less on their expected babies, they continued smoking.Conclusions: The smoking and socioeconomical status of women smoking during pregnancy in 2009-2013 has not changed, health awareness of them is low and has not improved. Support groups with close relatives are needed to motivate cessation. In the first place, prevention needs a good example, purposeful cooperation, which starts in daily life context – at homes, in educational institutions and in the community. Limiting the availability of tobacco products, postponing and preventing an initial exposure to smoking are thought to be of great importance. The results of the research will be introduced in health care institutions and they can be used in the health promotion process.
To determine the frequency pattern of presentation and causative agents of lower urinary tract symptoms in pregnant females. One thousand consecutive pregnant women, attending the antenatal clinics of Fatima Memorial Hospital, were included in the study. Women with renal pathology, postrenal transplant and those on immunosuppressive agents were excluded. All women underwent complete examination of urine. Those who had one or more urinary complaints had culture and sensitivity test of urine. Other variables studied were the symptomatology. Out of one thousand pregnant women, 426 (42.6%) complained of one or more urinary symptoms. Diurnal and nocturnal frequency was the most commonly encountered symptom (87.32%), followed by irritative symptoms and voiding difficulties. Complete urine examination of symptomatic patients revealed < 5 pus cells /HPF (high power field) in 322 cases and 6-20 pus cell/HPF in the remaining 104 cases. The urine culture of the symptomatic patients (426 cases) showed growth in only 37 cases (8.69%). Escherichia (E.) coli was the commonest organism (89.1%) followed by Staphylococcus (S.) aureus (8.1%) and candidiasis (2.7%). (author)
Helle Margrete Meltzer
Full Text Available Pregnant women and infants are exceptionally vulnerable to iodine deficiency. The aims of the present study were to estimate iodine intake, to investigate sources of iodine, to identify predictors of low or suboptimal iodine intake (defined as intakes below 100 ?g/day and 150 ?g/day in a large population of pregnant Norwegian women and to evaluate iodine status in a sub-population. Iodine intake was calculated based on a validated Food Frequency Questionnaire in the Norwegian Mother and Child Cohort. The median iodine intake was 141 ?g/day from food and 166 ?g/day from food and supplements. Use of iodine-containing supplements was reported by 31.6%. The main source of iodine from food was dairy products, contributing 67% and 43% in non-supplement and iodine-supplement users, respectively. Of 61,904 women, 16.1% had iodine intake below 100 ?g/day, 42.0% had iodine intake below 150 ?g/day and only 21.7% reached the WHO/UNICEF/ICCIDD recommendation of 250 ?g/day. Dietary behaviors associated with increased risk of low and suboptimal iodine intake were: no use of iodine-containing supplements and low intake of milk/yogurt, seafood and eggs. The median urinary iodine concentration measured in 119 participants (69 ?g/L confirmed insufficient iodine intake. Public health strategies are needed to improve and secure the iodine status of pregnant women in Norway.
Brantsæter, Anne Lise; Abel, Marianne Hope; Haugen, Margaretha; Meltzer, Helle Margrete
Pregnant women and infants are exceptionally vulnerable to iodine deficiency. The aims of the present study were to estimate iodine intake, to investigate sources of iodine, to identify predictors of low or suboptimal iodine intake (defined as intakes below 100 ?g/day and 150 ?g/day) in a large population of pregnant Norwegian women and to evaluate iodine status in a sub-population. Iodine intake was calculated based on a validated Food Frequency Questionnaire in the Norwegian Mother and Child Cohort. The median iodine intake was 141 ?g/day from food and 166 ?g/day from food and supplements. Use of iodine-containing supplements was reported by 31.6%. The main source of iodine from food was dairy products, contributing 67% and 43% in non-supplement and iodine-supplement users, respectively. Of 61,904 women, 16.1% had iodine intake below 100 ?g/day, 42.0% had iodine intake below 150 ?g/day and only 21.7% reached the WHO/UNICEF/ICCIDD recommendation of 250 ?g/day. Dietary behaviors associated with increased risk of low and suboptimal iodine intake were: no use of iodine-containing supplements and low intake of milk/yogurt, seafood and eggs. The median urinary iodine concentration measured in 119 participants (69 ?g/L) confirmed insufficient iodine intake. Public health strategies are needed to improve and secure the iodine status of pregnant women in Norway. PMID:23389302
Souza, Rodrigo Batista; Trevisol, Daisson José; Schuelter-Trevisol, Fabiana
The aim this study was to determine the in vitro susceptibility to fosfomycin of bacteria isolated from urine samples of pregnant women with urinary tract infection. Samples of urine culture with bacterial growth of pregnant women were collected from clinical laboratories in Tubarão, state of Santa Catarina, Brazil, between September 2012 and May 2013. In the experimental stage, the colonies were tested for sensitivity to fosfomycin by using the Kirby-Bauer method. The following information relating to the samples was also collected: patients' age, colony count, type(s) of identified bacterial(s) and result of the antimicrobial sensitivity test. Student's t-test was used for mean comparison. A total of 134 samples were selected for the study. The age of the subjects ranged from 15 to 40 years (mean 26.7). Escherichia coli (Gram-negative) and Staphylococcus aureus (Gram-positive) were the most commonly identified species. In 89% of cases, the microorganisms were sensitive to fosfomycin. E. coli and S. aureus were the main species of bacteria responsible for urinary tract infections in women in the study area. The most prevalent microorganisms in pregnant women with urinary tract infection were susceptible to fosfomycin. PMID:25626961
Hee, Lene; Sandager, Puk
OBJECTIVE: To determine the stiffness of the pregnant uterine cervix in vivo. METHOD: Five women in early pregnancy and six women in late pregnancy were included. The EndoFlip is a 1-m-long probe with a 12-cm-long bag mounted on the tip. The tip of the probe was inserted into the cervical canal. Sensors spaced at 0.5-cm intervals along the probe were used to determine 16 serial cross-sectional areas of the bag. The diameter of the cervical canal could thereby be determined during inflation with up to 50 ml saline solution. Tissue stiffness was calculated from the geometric profiles and the pressure-strain elastic modulus (EP) at each sensor site. Three parts of the cervix were defined: the uterus-near part, the middle and the vaginal part. The EPmax was defined as the highest EP detected along the cervical canal. RESULTS: The EPmax was always found in the middle part of the cervix. The median EPmax was 243 kPa (IQR, 67-422 kPa) for the early pregnant women and 5 kPa (IQR, 4-15 kPa) for those at term. In theearly pregnant women the stiffness differed along the cervical length (p<0.05) whereas difference along the cervix was not found for late pregnant women. A positive correlation coefficient (Spearman's rho) was established between the EPs of the uterus-near and the middle part (0.84), between the vaginal and the middle part (0.81), and between the uterus-near and the vaginal part (0.85). CONCLUSION: This new method can estimate the stiffness along the cervical canal in vivo. This method may be useful in the clinical examination of the biomechanical properties of the uterine cervix.
Yadav R. J
Full Text Available Research Question: What is the coverage level of immunization and other maternal services by a modified technique developed by IRMS (ICMR Delhi in comparison to standard WHO technique. Objectives: To study the â€"Coverage level for immunization, antenatal care and IFA tablets â€"Relationship of caste and education with the coverage levels. â€"Place and persons conducting deliveries. Study design: Cross-sectional. Setting: Both in rural and urban areas of Bihar. Participants: 375 mothers having children up to one year of age selected by a stratified random sampling technique developed by IRMS Delhi. Study variables: Immunisation status, antenatal care, Use of IFA tabs, Education of the female, Education of husband, place and person conducting the delivery. Statistical analysis: Proportions. Results: Overall immunization coverage was 42% for pregnant females. Coverage was high (60% in urban areas compared to rural areas (40%. Coverage was low among females from SC/ST category, also when females and their husbands were illiterates. Similar trend was observed for antenatal care and IFA tabs. 90% deliveries took place at home and were mainly attended by village dais. Majority of mothers received immunization from some. Govt. agency lack of, awareness and lack of motivation were more commonly found as reasons for non-immunisation among SC/ST as compared to others. Lack of awareness was also found as a common reason for non-immunisation among illiterate females.
McGowan, C A
Vitamin D has an important role in pregnancy in promoting fetal skeletal health. Maternal dietary intake is a key factor influencing both maternal and fetal status. There are limited data available on food groups contributing to vitamin D intake in pregnancy. The aim of this study was to determine dietary intakes of vitamin D throughout pregnancy in 64 women and to determine the main food groups contributing to vitamin D intake. Results showed that median dietary intakes of vitamin D ranged from 1.9-2.1??g\\/d during pregnancy, and were 80% below the current recommendation. The principal food groups contributing to vitamin D intake were meat, egg and breakfast cereal groups. Oily fish, the best dietary source of vitamin D, was consumed by <25% of women. These data call for more education; they question the role of vitamin D supplementation and highlight the contribution of other food groups more frequently consumed, namely, breakfast cereals, meat and eggs.
Rosvold Elin; Lindbæk Morten; Hjerkinn Bjørg
Abstract Background Substance abuse during pregnancy may harm the foetus and can cause neonatal abstinence syndrome. Exposure to alcohol and other substances can influence the child for the rest of its life. A special child welfare clinic was set up in 1994 in Kristiansand, Norway, targeting pregnant women with substance abuse problems in the county of Vest-Agder. Pregnancy is not an indication for opioid replacement therapy in Norway, and one of the clinic's aims was to support the drug depe...
Kim, Eun-Young; Kogan, Sandra; Cristiano, Lynda M.; Kitch, Barrett T.; Zeng, Qing
Management of chronic illness presents a challenge to patients. Asthma is a common chronic disease affecting millions of Americans each year. Particularly, maternal asthma puts pregnant women at high risk for many complications and requires special day-to-day management. Tailored materials are shown to be an effective means of communication between patients and physicians. To improve asthma management in this high-risk group, we developed a web-based tool to facilitate the creation and dissem...
Full Text Available Managing medical complications in pregnancy is a challenge to clinicians. Objectives: This study profiled some disease and prescription patterns for pregnant women attending antenatal clinics (ANCs in Nigeria. A risk classification of the medicines was also determined. Methods: Medical case files of 1,200 pregnant women attending antenatal clinics of 3 health facilities in Benin City, Nigeria were investigated. Disease pattern was determined from their diagnoses. The prescription pattern was assessed using WHO indicators, and the United States Food and Drug Administration classification of medicines according to risk to the foetus. Results: A total of 1,897 prescriptions of the 1,200 pregnant women attendees during the period under review were evaluated. Results indicated that malaria 554 (38% was the most prevalent disease, followed by upper respiratory tract infections (URTIs, 13% and gastrointestinal disturbances (GIT, 12%. The average number of drugs prescribed per encounter was found to be 3.0, and 2,434 (43% of medicines were prescribed by generic name. Minerals/ Vitamins 2,396 (42% were the most frequently prescribed medicines, and antibiotics occurred in 502 (8.8% of the total medicines. Of all medicines prescribed, 984 (17% were included in the foetal risk category C and 286 (5% in category D. Conclusion: The study concluded that malaria fever occurred most frequently followed by URTIs and GIT disturbances among the pregnant women. Minerals, vitamins and to a less extent anti-malarials topped the list of the prescribed medicines. The average number of medicines per encounter was much higher than WHO standards. The occurrence of contraindicated medicines was low.
Nde, Peter F; Vucha C. Yugah; Dickson S. Nsagha; Henri L.F. Kamga; Jules C.N. Assob; Njunda, Anna L.
Toxoplasmosis is caused by an intracellular protozoan, Toxoplasma gondii, which has a wide geographical distribution. The congenital form results in a gestational form that can present a temporary parasiteamia that will infect the fetus. For this reason early diagnosis in pregnancy is highly desirable, allowing prompt intervention in cases of infection. The aim of this study was to determine the seroprevalence of Toxoplasma gondii antibodies among pregnant women attending the Douala General H...
ABSTRACTSmoking during pregnancy is an important, preventable risk factor for late fetal death and even SIDS.There is a strong dose-response relationship between cigarette smoking and spontaneous abortion,reduction in birth weight, abruptio placentae, placenta previa and bleeding during pregnancy. Ten yearsago, the prevalence of smoking among Norwegian pregnant women was between 35 and 40%. Duringthe last 8 years there has been a dramatic change and in 1995 the prevalence seems to be around ...
Full Text Available ABSTRACTSmoking during pregnancy is an important, preventable risk factor for late fetal death and even SIDS.There is a strong dose-response relationship between cigarette smoking and spontaneous abortion,reduction in birth weight, abruptio placentae, placenta previa and bleeding during pregnancy. Ten yearsago, the prevalence of smoking among Norwegian pregnant women was between 35 and 40%. Duringthe last 8 years there has been a dramatic change and in 1995 the prevalence seems to be around 20%.
Lou, Stina; Mikkelsen, Line; Hvidman, Lone; Petersen, Olav Bjørn; Nielsen, Camilla Palmhøj
BACKGROUND: Prenatal screening for Down's syndrome and other chromosomal abnormalities is included in prenatal care programs in many countries. However, the potential association between prenatal screening and maternal anxiety remains an issue of debate. OBJECTIVE: To systematically review and summarize the current scientific evidence on whether screening for Down's syndrome might cause anxiety in pregnant women with a negative or a false-positive screening result. METHODS: Five databases (PubMe...
This outline review concludes that pregnancy is a major contra-indication for any diagnostic procedures. The only exception is a perfusion scintigraphy of the lungs, when a pulmonary embolism is suspected. Accidental exposures of the embryo should be guarded against by implementing the ten day rule for diagnostic examinations of fertile women at risk of pregnancy. In the event of clinical emergencies resulting in radiation of an early developing embryo, reconstruction of the received dose is essential. A foetal dose of 10 rads or more is usually considered as an indication of a therapeutic abortion, while doses below 1 rad can probably be neglected. (U.K.)
Full Text Available Abstract Background In areas where malaria is endemic, pregnancy is associated with increased susceptibility to malaria. It is generally agreed that this risk ends with delivery and decreases with the number of pregnancies. Our study aimed to demonstrate relationships between malarial parasitaemia and age, gravidity and anaemia in pregnant women in Libreville, the capital city of Gabon. Methods Peripheral blood was collected from 311 primigravidae and women in their second pregnancy. Thick blood smears were checked, as were the results of haemoglobin electrophoresis. We also looked for the presence of anaemia, fever, and checked whether the volunteers had had chemoprophylaxis. The study was performed in Gabon where malaria transmission is intense and perennial. Results A total of 177 women (57% had microscopic parasitaemia; 139 (64%of them were primigravidae, 38 (40% in their second pregnancy and 180 (64% were teenagers. The parasites densities were also higher in primigravidae and teenagers. The prevalence of anaemia was 71% and was associated with microscopic Plasmodium falciparum parasitaemia: women with moderate or severe anaemia had higher parasite prevalences and densities. However, the sickle cell trait, fever and the use of chemoprophylaxis did not have a significant association with the presence of P. falciparum. Conclusions These results suggest that the prevalence of malaria and the prevalence of anaemia, whether associated with malaria or not, are higher in pregnant women in Gabon. Primigravidae and young pregnant women are the most susceptible to infection. It is, therefore, urgent to design an effective regimen of malaria prophylaxis for this high risk population.
Objective: To evaluate the drug use habit of pregnant women in villages of central India. Methods: An observational, cross sectional study was conducted among six hundred fifty pregnant women from different randomly selected villages of Wardha district of central India through interviews on medicine use behaviour and evaluation of prescriptions. Results: Pregnant women of younger age group from lower socio economic status constituted the majority of the study population. Major portion (97.7) of this socio economically backward population followed the doctor's advice as far as dose, frequency and duration of the drug was concerned. The antenatal mothers were of the opinion that, if the instructions on the drug envelop or foil was in written in the local language, it could be more helpful for them. Conclusion: Majority of the study population used drugs or medicines regularly but some mothers were reluctant. This indicated that even in this age of advancement of scientific knowledge, all antenatal mothers were not conversant with the advantages of drug use. (author)
Gross Karin; Alba Sandra; Glass Tracy R; Schellenberg Joanna; Obrist Brigit
Abstract Background Early and frequent antenatal care attendance during pregnancy is important to identify and mitigate risk factors in pregnancy and to encourage women to have a skilled attendant at childbirth. However, many pregnant women in sub-Saharan Africa start antenatal care attendance late, particularly adolescent pregnant women. Therefore they do not fully benefit from its preventive and curative services. This study assesses the timing of adult and adolescent pregnant women's first...
Leppert Jill; Rockett Helaine RH; Blum Robin E; Baer Heather J; Gardner Jane D; Suitor Carol W; Colditz Graham A.
Abstract Background Food frequency questionnaires (FFQs) have been validated in pregnant women, but few studies have focused specifically on low-income women and minorities. The purpose of this study was to examine the validity of the Harvard Service FFQ (HSFFQ) among low-income American Indian and Caucasian pregnant women. Methods The 100-item HSFFQ was administered three times to a sample of pregnant women, and two sets of 24-hour recalls (six total) were collected at approximately 12 and 2...
Petersen, Lone Kjeld; Uldbjerg, N
OBJECTIVE: To study the cervical collagen in non-pregnant women with a history of congenital cervical incompetence. SUBJECTS: Ten non-pregnant women with congenital cervical incompetence, defined as cervical incompetence in the first pregnancy in a woman without previous cervical trauma. Seventy-one normal non-pregnant women (31 nulligravidae, nine nulliparous and 31 parous women) served as controls. METHOD: Cervical biopsies were analysed for the hydroxyproline concentration and extractability ...
Full Text Available Rubella a benign viral and modestly contagious illness in children, becomes a very dangerous story when acquired by pregnant women. The potential of its teratogenicity is obvious. Since prevention is preferred to treatment, diagnosis of rubella infection syndrome being difficult in early stages of pregnancy, the uncertainly about fetuses being really infected and therapeutic abortion because of fetal indication being prohibited by law in our country in a descriptive study, the rubella antibody titer (IgG-HI assay was measured in 500 pregnant women referred to the prental clinic, shariatti Hospital. 76% of women were immune. The immune status improved with advancing age (P<0.01. More than half of these women had no information regarding their previous vaccination status. Only 25 percent reported of being vaccinated, of which, 40 percent was done at 1.5 years of age. No one had been vaccinate in postpartum period. With regard to the results , it is proposed to immunize all children in the second year of life, at preschool ently or high school, screen women in prepubertal, premarried, prenatal period, in the family planning centers and health care places and vaccinate them at appropriae time.
Victoria V. Barinova
Full Text Available Background: The role of subchorionic hematoma (SCH in the first trimester of pregnancy remains open for discussion. Some authors claim that SCH does not affect the pregnancy; others have found that it is a serious risk factor for adverse pregnancy outcome. The objective of the present study was to explore the outcomes of pregnancy in patients with SCH diagnosed in the first trimester. Methods and Results: The study involved 194 pregnant women who were in terms of 6 to12 weeks: 115 women with SCH (Group 1 and 79 apparently healthy pregnant women (Group 2. A missed miscarriage was observed in 27/23% women of Group 1 and in 4/5% of Group 2 (P<0.05, recurrent threat of miscarriage in 27/23% and in 4/5%, recurrent bleeding in 14/12% and 2/3%, and the short cervix syndrome in 22/19% and 5/6% women, respectively. Conclusion: The results of our study show that the presence of SCH adversely affects the first half of pregnancy, leading to recurrent threatened abortion, recurrent threat of miscarriage, missed miscarriage until 12 weeks of gestation, and the short cervix syndrome.
Azizeh Farshbaf Khalili
Full Text Available Introduction: Down syndrome is one of the most prevalent genetic diseases. Screening methods for this syndrome are easy and safe and are recommended to all pregnant wom-en particularly mothers over 35 years of age. This study aimed to review the status of Down syndrome screening and related factors in Iranian pregnant women. Methods: This descriptive analytical study was carried out in 2011. It included 400 women who were randomly selected from those referring to Alzahra Hospital (Tabriz, Iran during their third trimester of pregnancy. Data was collected through a question-naire whose reliability and validity have been approved. The data was analyzed by chi-square test in SPSS13. Results: The results showed that while 28 and 26 women imple-mented screening tests during the first and second trimesters, respectively, only 5 sub-jects benefited from both (integrated test. Chi-square test showed significant correla-tions between the implementation of screening methods and age, education level, in-come, and the location of prenatal care (p < 0.05. Conclusion: The findings of the present study showed women to poorly implement Down syndrome screening methods. Therefore, the necessity of providing appropriate educational programs for health staff and mothers seems undeniable. Moreover, paying attention to the related factors such as income, educational level, and adequate training of mothers during pregnancy is essential.
Full Text Available Although pregnancy was once thought to protect against psychiatric disorders, gravid and non gravid women have similar risks for major depression, at 10% to 15%. Both depression and antidepressant treatment during pregnancy have been associated with risks. Few medications have been proved unequivocally safe during pregnancy. Although certain antidepressants have not been linked with an increased risk of birth defects or impaired development including bupropion, citalopram, escitalopram and venlafaxine, the latest studies aren't necessarily reassuring. As researchers continue to learn more about antidepressants, the risks and benefits of taking the drugs during pregnancy must be weighed carefully on a case-by-case basis. This review discusses about the use of new generation of antidepressants in pregnancy
R. N. Bogdanovich
Full Text Available Abstract. The level of trophoblastic ?1 – glycoprotein (SP–1 was determined in the blood sera of 200 healthy pregnant women and 184 women with threatened abortions in term till 20 weeks of pregnancy. In group of women experiencing recurrent abortions in 38 % cases antibodies to chorionic gonadotropin, in 39,5 % cases antibodies to phospholipids, in 25,5 % – antibodies to tireoglobulin were revealed in significant amounts. In 20,65 % lupus anticoagulant was found. The majority of women in this group had changes in homeostasis. The presence of autoantibodies during pregnancy is the unfavourable factor in the development of placental insufficiency. This is proved by the decreased secretion of trophoblastic ?1 – glycoprotein – a marker of the fetal part of placenta. (Med. Immunol., 2005, vol.7, ? 1, pp. 85588
To investigate whether normal pregnancy has a significant effect on intrarenal venous blood flow and to assess whether the physiological maternal pyelocaliectasis causes a measurable change in venous impedance indices in pregnant women. Study Design: Cross sectional comparative study. Place and duration of study: Radiology Departments, KRL Hospital Islamabad and Combined Military Hospital Lahore from Jan 2010 to Jul 2010 Patients and Methods: A total of 50 normal pregnant women in their second and third trimester and 50 controls, i.e. normal non-pregnant married healthy women of childbearing age were included in the study. Confounding variables were controlled by excluding subjects having recent or previous renal calculi, pathological renal conditions or congenital renal anomalies or generalized disorders affecting haemodynamics ruled out by history, clinical examination and ultrasound examination in both pregnant and non-pregnant women. Results: After grading the degree of hydronephrosis, venous impedance index was obtained from the interlobar veins. Overall the collecting system dilatation was present in 60 % of 50 right kidneys and 42 % of 50 left kidneys in the pregnant women. The venous impedance indices were significantly lower in 50 pregnant women than the values in non-pregnant subjects (p< 0.001 for the right and the left kidney). The overall difference in venous impedance indices between right and left kidneys was not significant in pregnant women (p = 0.11). There was an inverse correlation between the grade of pelvicalyceal dilatation and the venous impedance indices in both kidneys in 50 pregnant women. Conclusion: Normal pregnancy causes dilatation of the pelvicalyceal system and significant reduction in renal venous impedance index values in second and third trimesters. Therefore one should be careful in interpretation of an abnormally reduced venous impedance index and hydronephrosis as a sign of pathological ureteral obstruction in pregnant women. (author)
Full Text Available Abstract Background Pregnant women are at an increased risk for HIV infection due to unknown biological causes. Given the strong effect of sex-hormones on the expression of immunomuodulatory factors, the central role of mucosal immunity in HIV pathogenesis and the lack of previous studies, we here tested for differences in immunomuodulatory factors in cervico-vaginal secretions between pregnant and non-pregnant women. Methods We compared concentrations of 39 immunomodulatory factors in cervicovaginal lavages (CVL from 21 pregnant women to those of 24 non-pregnant healthy women from the US. We used Bonferroni correction to correct for multiple testing and linear regression modeling to adjust for possible confounding by plasma cytokine concentration, cervical ectopy, total protein concentration, and other possible confounders. Cervical ectopy was determined by planimetry. Concentration of immunomodulatory factors were measured by a multiplex assay, protein concentration by the Bradford Method. Results Twenty six (66% of the 39 measured immunomodulatory factors were detectable in at least half of the CVL samples included in the study. Pregnant women had threefold lower CVL concentration of CCL22 (geometric mean: 29.6 pg/ml versus 89.7 pg/ml, p = 0.0011 than non-pregnant women. CVL CCL22 concentration additionally correlated negatively with gestational age (Spearman correlation coefficient [RS]: -0.49, p = 0.0006. These associations remained significant when corrected for multiple testing. CCL22 concentration in CVL was positively correlated with age and negatively correlated with time since last coitus and the size of cervical ectopy. However, none of these associations could explain the difference of CCL22 concentration between pregnant and non-pregnant women in this study, which remained significant in adjusted analysis. Conclusions In this study population, pregnancy is associated with reduced concentrations of CCL22 in cervicovaginal secretions. The role of CCL22 on HIV transmission should now be investigated in prospective studies.
Objective: To differentiate the effect of gestation on the mode of delivery by analysing the difference in the mode of induction, length of labour and the difference in parity or Bishop score and their effect on the mode of delivery of postdates women. Study Design: A cross-sectional observational study. Place and Duration of Study: PAEC General Hospital, Islamabad, from July 2006 to July 2008. Methodology:Patients were induced at 41 weeks (Group B) and > 40 weeks (Group A) of gestation. Tab misoprostol and PGE2 tablets were administered according to amniotic fluid index (AFI) and parity . Study variables included duration of gestation, mode of induction, length of labour, difference in parity and Bishop score assessed before induction in each group. The outcome was assessed by applying Chi-square test by comparing mode of delivery with the study variables in both groups. Results: A total of 78 patients were inducted in the study. They were divided in group B (n = 39) induced 41 weeks and group A (n = 39) induced at 40 weeks. Eighty four percent (n = 35) patients in group B delivered vaginally as compared to 71% (n = 28) in the 40 weeks group (p < 0.0001). The higher number of vaginal deliveries in 41 weeks group was independent of association between the induction agent, parity and mode of delivery. Conclusion: The mean length of gestation was the single most important factor among the studied variables in predicting a vaginal delivery. (author)
M. Nojomi Z. Akrami
Violence and the threat of violence against pregnant women are main barriers to women’s empowerment and equal participation in society. When stress and violence increase in developing societies, women’s safety in the home, workplace and community is often seriously affected. To determine the prevalence of physical abuse in pregnant women and to assess association between physical violence during pregnancy and maternal complications and birth outcomes, we used clinicbased data from a sample of...
Petersen, Kathrine Birch; Johansen, Helle Krogh
INTRODUCTION: Group B streptococci (GBS) can cause preterm delivery for women and sepsis and meningitis in infants younger than 90 days of age. The present retrospective cohort study determines the trend over time in the rates of GBS and in demographic risk factors for GBS among pregnant women delivering at Rigshospitalet (RH). MATERIAL AND METHODS: In the period from 2002 to 2010, a total of 33,616 women gave birth at the RH. Our cohort was defined as 16,587 (49%) women examined by 24,724 cultures. All microbiological requisitions from the Department of Obstetrics at RH were extracted from the Clinical Microbiology Database. Maternal data were obtained from a local database at the RH. RESULTS: In our cohort, a total of 638 (3.8%) women were diagnosed with GBS, 517 (81%) from urine, 92 (14%) from vaginal swabs and 29 (5%) from both. The overall rate of women colonised with GBS rose from 3.3% in 2002 to 5.1% in 2010 (p < 0.0001). A total of 48 infants had early-onset group B streptococcus (EOGBS), 1.4 per 1,000 neonates in the general population and 7.8 per 1,000 among women with GBS (p < 0.0001). CONCLUSION: We found a low GBS colonisation rate in our pregnant cohort, but the rate followed an increasing trend over the study period. GBS during pregnancy was associated with a low birth weight and preterm delivery. More research on preventive measures is needed, but updated guidelines, screening and intrapartum antibiotic prophylaxis continue to be the cornerstones of EOGBS disease prevention. FUNDING: not relevant. TRIAL REGISTRATION: not relevant.
Williams, Marissa E; Becker, Suzanna; McKinnon, Margaret C; Wong, Queenie; Cudney, Lauren E; Steiner, Meir; Frey, Benicio N
Postpartum depression (PPD) is associated with debilitating effects on mothers and their infants. A previous history of depression is considered the strongest risk factor for PPD. Depressed individuals recall more negative than positive content and higher levels of stress hormones released during encoding are associated with enhanced recall of emotional stimuli. This study examined the impact of a previous history of major depressive disorder (MDD) and pregnancy on emotional memory. Seventy-seven participants completed the study [44 pregnant women in the second trimester of pregnancy with and without a lifetime history of MDD and 33 non-pregnant women with and without a lifetime history of MDD]. All completed an encoding task and provided salivary cortisol (sCORT) and alpha-amylase (sAA) samples. Participants returned one week later for a surprise incidental recognition memory task. Women with a history of MDD had worse recognition than women without a history of MDD for negative, but not positive images; this effect was independent of sCORT and sAA levels. Pregnancy did not affect emotional memory. Considering that several previous studies found enhanced memory bias for negative content during depressive states, our results suggest that clinical remission may be associated with an opposite cognitive processing of negative emotional content. PMID:26272023
Rasch, V; Knudsen, L B
OBJECTIVE: To study how living conditions influence pregnancy planning and acceptance among Danish women. METHOD: A cross-sectional questionnaire study performed among 3516 pregnant women attending Odense University Hospital, Denmark. The study population consisted of women with spontaneous abortion, women with ectopic pregnancies, women attending antenatal care and women with induced abortion. They were divided into four groups: women with planned and accepted pregnancies (accepting planners, n=2137), women who accepted an initially unplanned pregnancy (accepting non-planners, n=1006), women who rejected an initially planned pregnancy (rejecting planners, n=31), and women with unplanned and rejected pregnancies (rejecting non-planners, n=342). The association between socio-economic characteristics and pregnancy planning and acceptance was evaluated by comparing accepting non-planners with accepting planners and by comparing rejecting planners with rejecting non-planners. The variables studied comprise age, number of children, partner relationship, education, occupation, economic situation and contraceptives. RESULTS: The characteristics of accepting non-planners and accepting planners were in accordance and in contrast to those of rejecting planners and in particular of rejecting non-planners. The contraceptive prevalence rate among accepting non-planners was 15%. Among rejecting non-planners the same figure was 51%. CONCLUSION: Accepting non-planners seemed to be in a situation which could be considered appropriate for childbirth. The contraceptive prevalence rate among accepting non-planners was low and might reflect that these women were not entirely against the thought of having a child, although they did not actively plan to have one.
Datner, Elizabeth M.; Wiebe, Douglas J.; Brensinger, Colleen M.; Nelson, Deborah B.
The article describes characteristics of pregnant women presenting to the Emergency Department (ED) who are experiencing current violence and presented a screening tool to identify pregnant women experiencing violence. Women completed an in-person interview regarding violence, sociodemo-graphic factors, health status, and drug use. Fifteen percent…
Hinwood, A.L., E-mail: firstname.lastname@example.org [Centre for Ecosystem Management, Edith Cowan University, 270 Joondalup Drive, Joondalup, WA 6027 (Australia); Callan, A.C.; Ramalingam, M.; Boyce, M. [Centre for Ecosystem Management, Edith Cowan University, 270 Joondalup Drive, Joondalup, WA 6027 (Australia); Heyworth, J. [School Population Health, The University of Western Australia, 35 Stirling Highway Crawley, WA 6009 (Australia); McCafferty, P. [ChemCentre, PO Box 1250, Bentley, WA 6983 (Australia); Odland, J.Ø. [Department of Community Medicine, University of Tromsø, N-9037 Tromsø (Norway)
Recent literature suggests that exposure to low concentrations of heavy metals may affect both maternal and child health. This study aimed to determine the biological heavy metals concentrations of pregnant women as well as environmental and dietary factors that may influence exposure concentrations. One hundred and seventy three pregnant women were recruited from Western Australia, each providing a sample of blood, first morning void urine, residential soil, dust and drinking water samples. Participants also completed a questionnaire which included a food frequency component. All biological and environmental samples were analysed for heavy metals using ICP-MS. Biological and environmental concentrations of lead and mercury were generally low (Median Pb Drinking Water (DW) 0.04 µg/L; Pb soil <3.0 µg/g; Pb dust 16.5 µg/g; Pb blood 3.67 µg/L; Pb urine 0.55; µg/L Hg DW <0.03; Hg soil <1.0 µg/g; Hg dust <1.0 µg/g; Hg blood 0.46 µg/L; Hg urine <0.40 µg/L). Cadmium concentrations were low in environmental samples (Median CdDW 0.02 µg/L; Cdsoil <0.30 ug/g; Cddust <0.30) but elevated in urine samples (Median 0.55 µg/L, creatinine corrected 0.70 µg/g (range <0.2–7.06 µg/g creatinine) compared with other studies of pregnant women. Predictors of increased biological metals concentrations in regression models for blood cadmium were residing in the Great Southern region of Western Australia and not using iron/folic acid supplements and for urinary cadmium was having lower household annual income. However, these factors explained little of the variation in respective biological metals concentrations. The importance of establishing factors that influence low human exposure concentrations is becoming critical in efforts to reduce exposures and hence the potential for adverse health effects. -- Highlights: • Biological heavy metals concentrations in women in their 3rd trimester of pregnancy. • Exposure assessment including environmental, lifestyle and activity data. • Urinary cadmium concentrations were elevated in this group of pregnant women. • Blood lead and mercury concentrations were below recommended biological guideline values.
Recent literature suggests that exposure to low concentrations of heavy metals may affect both maternal and child health. This study aimed to determine the biological heavy metals concentrations of pregnant women as well as environmental and dietary factors that may influence exposure concentrations. One hundred and seventy three pregnant women were recruited from Western Australia, each providing a sample of blood, first morning void urine, residential soil, dust and drinking water samples. Participants also completed a questionnaire which included a food frequency component. All biological and environmental samples were analysed for heavy metals using ICP-MS. Biological and environmental concentrations of lead and mercury were generally low (Median Pb Drinking Water (DW) 0.04 µg/L; Pb soil <3.0 µg/g; Pb dust 16.5 µg/g; Pb blood 3.67 µg/L; Pb urine 0.55; µg/L Hg DW <0.03; Hg soil <1.0 µg/g; Hg dust <1.0 µg/g; Hg blood 0.46 µg/L; Hg urine <0.40 µg/L). Cadmium concentrations were low in environmental samples (Median CdDW 0.02 µg/L; Cdsoil <0.30 ug/g; Cddust <0.30) but elevated in urine samples (Median 0.55 µg/L, creatinine corrected 0.70 µg/g (range <0.2–7.06 µg/g creatinine) compared with other studies of pregnant women. Predictors of increased biological metals concentrations in regression models for blood cadmium were residing in the Great Southern region of Western Australia and not using iron/folic acid supplements and for urinary cadmium was having lower household annual income. However, these factors explained little of the variation in respective biological metals concentrations. The importance of establishing factors that influence low human exposure concentrations is becoming critical in efforts to reduce exposures and hence the potential for adverse health effects. -- Highlights: • Biological heavy metals concentrations in women in their 3rd trimester of pregnancy. • Exposure assessment including environmental, lifestyle and activity data. • Urinary cadmium concentrations were elevated in this group of pregnant women. • Blood lead and mercury concentrations were below recommended biological guideline values
Full Text Available From a feminist perspective, research on childbirth and women's health is a means to a positive change that is conducted in partnership with women for their benefit. A patient-led National Health System (NHS) (Hillan, 1999) also calls for consultation with patients and the wider public for shaping t [...] he current and future health services. This study was aimed at exploring and describing the expectations that pregnant women have regarding antenatal care service by the midwife practitioner. In-depth interviews were conducted in an antenatal unit of an Academic Hospital in Gauteng Povince. Data saturation was reached with a sample of eighteen pregnant women who were conveniently selected. Data analysis ran concurrently with data collection. A manual content analysis as described by Tesch was used. Lincoln and Guba's method of ensuring trustworthiness was adopted (Lincoln & Guba, 1985:328). Literature was undertaken to compare the findings of this study with those of other previous studies. Women displayed several common expectations that led to the saturation of data. It also became apparent from the findings that each woman had varied expectations. There were also some commonalities within the women's expectations. Health care, as the major expectation and a basic human right, appeared to be basically fulfilled, with the exception of interactional characteristics such as the communication of information, guidance, involvement, the understanding and explanation of aspects, freedom of choice, punctuality, individualized care and continuity of care. The conclusions that were reached let to recommendations for nursing practice, education, research and the formulation of guidelines for the midwife practitioner for the implementation of effective antenatal care, based on the identified expectations.
Full Text Available Abstract Background Over 20% of women smoke throughout pregnancy despite the known risks to mother and child. Engagement in face-to-face support is a good measure of service reach. The Scottish Government has set a target that by 2010 8% of smokers will have quit via NHS cessation services. At present less than 4% stop during pregnancy. We aimed to establish a denominator for pregnant smokers in Scotland and describe the proportion who are referred to specialist services, engage in one-to-one counselling, set a quit date and quit 4 weeks later. Methods This was a descriptive epidemiological study using routinely collected data supplemented by questionnaire information from specialist pregnancy cessation services. Results 13266 of 52370 (25% pregnant women reported being current smokers at maternity booking and 3133/13266 (24% were referred to specialist cessation services in 2005/6. Two main types of specialist smoking cessation support for pregnant women were in place in Scotland. The first involved identification using self-report and carbon monoxide breath test for all pregnant women with routine referral (1936/3352, 58% referred to clinic based support (386, 11.5% engaged. 370 (11% women set a quit date and 116 (3.5% had quit 4 weeks later. The second involved identification by self report and referral of women who wanted help (1195/2776, 43% referred for home based support (377/1954, 19% engaged. 409(15% smokers set a quit date and 119 (4.3% had quit 4 weeks later. Cost of home-based support was greater. In Scotland only 265/8062 (3.2% pregnant smokers identified at maternity booking, living in areas with recognised specialist or good generic services, quit smoking during 2006. Conclusions In Scotland, a small proportion of pregnant smokers are supported to stop. Poor outcomes are a product of current limitations to each step of service provision - identification, referral, engagement and treatment. Many smokers are not asked about smoking at maternity booking or provide false information. Carbon monoxide breath testing can bypass this difficulty. Identified smokers may not be referred but an opt-out referral policy can remove this barrier. Engagement at home allowed a greater proportion to set a quit date and quit, but costs were higher.
Dechen Tsering; Sumit Kar; Ranabir Pal
Background: A study of genital colonization by group B streptococcus (GBS) was conducted in pregnant women in their third trimester, which is a known risk factor of morbidity and mortality among newborns. Aims: The present study was undertaken to study the prevalence and the correlates of vaginal colonization by GBS among pregnant women. Setting and Design: This observational cross-sectional study was conducted during September 2002 to March 2004 on 524 pregnant women. Materials and Methods: ...
Akhlaghi Farideh; Hamedi Abdolkarim; Naderi Nasab Mahbobeh
- To Compare colonization of group B streptococcus (GBS) in diabetic and non-diabetic pregnant women. In this prospective study 50 pregnant women with diabetes mellitus (both pregestational and gestational) and 43 pregnant women without diabetes between 33 and 37 weeks' gestation were evaluated. Three samples for Group B streptococcal culture detection were obtained from each subject in the following order: perinea sample, vaginal sample, and an anorectic sample. All had singleton gestat...
Pregnant women living at northerly latitudes are at risk of suboptimal vitamin D status. There is a paucity of studies correlating knowledge, attitudes and practices of vitamin D with serum levels amongst pregnant women. We aimed to determine the prevalence of suboptimal vitamin D status in pregnant women of various ethnicities attending two Dublin maternity hospitals and to assess levels of knowledge, attitudes and practices concerning vitamin D.
Iclal Meram; Bozkurt, Ali I; Sibel Ahi; Servet Ozgur
OBJECTIVES Trace elements such as copper and zinc are important factors on the health of pregnant women, fetus and embryonic development. Since these elements have important influences on health of pregnant women and the growing fetus, this study was designed to evaluate the zinc and copper status of pregnant women in Gaziantep, Turkey. METHODS This study was designed as a prevalence study. Twenty-two health station region were chosen in 13 health centers in the province of Gaziantep...
Moslem pregnant women are inclined to fast during the month of Ramadan. Ketonuria and hypoglycemia are harmful in pregnancy. The aim of this study was to find out whether clinical symptoms and/ or calorie deficiency of fasting pregnant women before Eftar (ending of the daily fast) can accurately predict ketonuria and hypoglycemia. In a descriptive study, 185 volunteer fasting pregnant women in Ramadan of 1999 were tested just before Eftar taking into account their clinical symptoms, intake of...
Nor Azlin Mohamed Ismail; Hadijat Olaide Raji; Norashikin Abd Wahab; Norlaila Mustafa; Nor Azmi Kamaruddin; Muhammad Abdul Jamil
Background: Ramadan fasting for pregnant women with diabetes remains controversial and underreported. The objective of this study was to determine the glycemic control in pregnant diabetic women on insulin who fasted during Ramadan.Methods: This was a retrospective study carried out over a period of three years including pregnant diabetic women, who were on short-acting, intermediate-acting, or a combination of them, and opted to carry out Ramadan fasting. Glycemic control was assessed before...
Kalantar Enayat; Farhadifar Fariba; Nikkho Bahram
OBJECTIVES: Determine the prevalence of asymptomatic urinary tract infection (AUTI) among pregnant women. We also determined the antibacterial susceptibility of the isolates to various antibiotics and associated risk factors in AUTI. MATERIALS AND METHODS: One thousand five hundred and five consecutive pregnant women were included in the study. Mid-stream urine specimen for complete examination of urine was obtained. RESULTS: Of 1505 pregnant women, 134 (8.9%) had bacteriuria. The mean age of...
Yamaguchi Kotomi; Suganuma Nobuhiko; Ohashi Kazutomo
Abstract Background Striae gravidarum is a physiological skin change that many pregnant women experience during pregnancy. The striae are often accompanied by a reddish purple color during pregnancy, and then lose pigmentation and become atrophic in the long term after pregnancy. Striae gravidarum seems to be undesirable to many pregnant women. However, the impact of striae gravidarum on pregnant women who experience it has not been clarified. The aim of this study was to evaluate the impact ...
Andrew E Czeizel
Full Text Available Andrew E Czeizel1, Erzsébet H Puhó1, Ferenc Bánhidy21Foundation for the Community Control of Hereditary Diseases, 2Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, HungaryAbstract: There was a significant male excess in the newborns of pregnant women with severe chronic constipation during pregnancy compared to pregnant women without constipation and pregnant women with new onset severe constipation, during pregnancy.Keywords: constipation, pregnancy, birth outcomes, sex ratio, male excess
Full Text Available Summary Outdoor and indoor air pollution pollutants can be a potential cause to a lot of negative effects on the health of pregnant women and outcome of pregnancy. The objective of this paper was to estimate the influence of outdoor and indoor air pollution on the health of pregnant women and outcome of pregnancy. Material and Methods The study subjects were the pregnant women, non-smokers, who were not professionally exposed to air pollution. They were divided into the exposed group (n=189 and control group (n=178 during the exposure to outdoor air pollution. The data on exposure to sources of indoor air pollution (smoke produced by burning fossil fuels and passive smoking during pregnancy were obtained from the questionnaire. Data on health condition and outcome of pregnancy were obtained from medical records of tested pregnant women. Results. The research results have shown that the frequency of anemia (OR=6.76; 95% CI=1.28-7.72, upper respiratory symptoms (OR=9.53; 95% CI=1.32-3.8 and bleeding (OR=20.5; 95% CI=2.03-6.97 was significantly higher in pregnant women exposed to outdoor air pollution as compared with the control group. The occurrence of upper respiratory symptoms (OR=40.42; 95% CI=2.96-8.91 and bleeding (OR=53.21; 95% CI=4.3-15.73 was significantly higher in pregnant women who had been exposed to fossil fuel smoke. Exposure to passive smoking had significant influence on the development of upper respiratory symptoms (OR=34.58; 95% CI=3.05-11.66.
The aim of this study was to assess the association between the occurrence of hypertension (HTN) in pregnancy and antiphospholipid antibodies. We conducted a cross-sectional study of 100 pregnant women with their first pregnancy induced HTN and no history of thrombosis, renal disease or systemic autoimmune diseases. HTN was defined as blood pressure (BP) of 140/90 mmHg or higher on two measurements with 6 hours apart. Control group comprised of pregnant women without hypertension or proteinuria and without history of thrombosis or systemic autoimmune disease. Antiphospholipid Antibodies (Antiphospholipid IgG and IgM and anticardiolipin IgG and IgM) levels were measured in both groups. There were significantly higher titer of Antiphospholipid IgG and anticardiolipin IgG and IgM in case group (p<0.05). Antiphospholipid IgM had no difference between two groups (p=0.14). There were moderate but statistically significant correlation between blood pressure and parity (r=0.3; p=0.0001), gestational age and antiphospholipid IgM antibody level (r=0.3; p=0.02), and between gestational age and anticardiolipin IgM antibody level (r=0.28; p=0.002). We found elevated levels of IgG and IgM anticardiolipin and IgG antiphospholipid antibodies in pregnancy induced HTN, but level of antiphospholipid IgM antibody was not different in hypertensive and normotensive women. (author)
Mozhgan Rabani Bavojdan; Marjan Rabani Bavojdan; Mahnaz Zamani; Mohammad Reza Nainian; Marjan Jamali Motlagh; Amir Nik-Azin
Objective: To evaluate sexual function and its relationship with quality of life, and mental and physical health in pregnant women.Materials and methods: Obtained results showed that 59 (39/3%) pregnant women were "very dissatisfied", 25 (16/7%) women were "moderately dissatisfied", 64 (42/7 %) women were "both satisfied and unsatisfied", only 2 (1/3 %) women were relatively satisfied, and no one was "very satisfied". There is a significantly negative weak correlation between female sexual fu...
Rasch, Vibeke; Wielandt, Hanne; Knudsen, Lisbeth B.
AIMS: This study describes women with induced abortion and thereby elucidates how living conditions and contraceptive failure are associated with the choice of induced abortion in a population of Danish pregnant women. METHODS: The study population consisted of pregnant women attending Odense University Hospital. They were categorized in two groups: women with induced abortion (n = 373) and a reference group consisting of women with spontaneous abortion and antenatal care attendees (n = 2,176). ...
Full Text Available Purpose: In this study, it was aimed to describe the smoking status of women during pregnancy who had had delivery in the Gynecology and Obstetric Department of Konya Meram Medical Faculty of Selcuk University; their husbands are also investigated to identify their attitudes towards smoking.Material and Methods: This study was carried out on women who delivered between June 22, 2004 and Jaunary 31, 2005. During this period 830 infants were delivered. The ?nitial decision and attempt was to include all of these women in the study. However, because of several reasons only 600 (72.3% were included. Questions related to smoking in pregnancy, the educational status of their husbands and themselves, their socioeconomic status and the harmful effects of smoking that could affect their babies and themselves were asked in a face- to-face interview with the mothers on the first day after the parturition. The chi square test was used for statistical significance.Results: The percentage of women who had smoked at any time during pregnancy was 7.3%. The percentage of women who smoked throughout pregnancy period was 2.3%. The percentage of current smokers among the husbands of the responders was 56.7%. When the smoking status of husbands of the women who had smoked at any time during pregnancy was compared with non-smoker mothers, the percentage of current smokers was significantly higher (p<0.05. It was observed that women had difficulty expressing the harmful effects of smoking on their babies and themselves. The study subjects did not appear to have adequate advice or support from health care providers regarding giving up smoking or protecting themselves from environmental tobacco smoking. It was determined that the women who smoked during pregnancy were desirous to smoke after delivery as well.Conclusion: This situation shows that new plans such as giving education especially to pregnant women should be prepared.
Sow Sokhna; Li Tengfei; Salanti Ali; Magnouha Nellie; Cottrell Gilles; Guitard Juliette; Deloron Philippe; Tuikue Ndam Nicaise
Abstract Background Pregnant women develop protective anti-VSA IgG1 and IgG3 when infected by Plasmodium falciparum. The major target of IgG from serum of infected pregnant women is VAR2CSA. Methods In this study, ELISA was used to compare the level of VAR2CSA DBL5?- specific IgG subclasses at enrolment and at delivery in a cohort of pregnant women in Senegal. All antibody measures were analysed in relation to placental infection according to parity. Results The results show an interaction be...
Guitard, Juliette; Cottrell, Gilles; Magnouha, Nellie Moulopo; Salanti, Ali; Li, Tengfei; Sow, Sokhna; Deloron, Philippe; Tuikue Ndam, Nicaise
BACKGROUND: Pregnant women develop protective anti-VSA IgG1 and IgG3 when infected by Plasmodium falciparum. The major target of IgG from serum of infected pregnant women is VAR2CSA. METHODS: In this study, ELISA was used to compare the level of VAR2CSA DBL5epsilon- specific IgG subclasses at enrolment and at delivery in a cohort of pregnant women in Senegal. All antibody measures were analysed in relation to placental infection according to parity. RESULTS: The results show an interaction betwe...
Hebl, Michelle R; King, Eden B; Glick, Peter; Singletary, Sarah L; Kazama, Stephanie
A naturalistic field study investigated behavior toward pregnant (vs. nonpregnant) women in nontraditional (job applicant) and traditional (store customer) roles. Female confederates, who sometimes wore a pregnancy prosthesis, posed as job applicants or customers at retail stores. Store employees exhibited more hostile behavior (e.g., rudeness) toward pregnant (vs. nonpregnant) applicants and more benevolent behavior (e.g., touching, overfriendliness) toward pregnant (vs. nonpregnant) customers. A second experiment revealed that pregnant women are especially likely to encounter hostility (from both men and women) when applying for masculine as compared with feminine jobs. The combination of benevolence toward pregnant women in traditional roles and hostility toward those who seek nontraditional roles suggests a system of complementary interpersonal rewards and punishments that may discourage pregnant women from pursuing work that violates gender norms. PMID:18020792
Sabrina Maria Saueia Ferreira
Full Text Available Objective : The intake of adequate amounts of iodine during pregnancy is essential for the neurological development of the fetus. The aim of this study was to assess iodine nutrition status in pregnant women from the state of São Paulo, Brazil.Material and methods : We analyzed urinary iodine concentration (UIC in 191 pregnant and 58 non-pregnant women matched by age. We used the World Health Organization criteria to define sufficient iodine supply (median UIC: 150-249 µg/L among pregnant women, and 100-199 µg/L for non-pregnant women.Results : Median UIC of the pregnant women studied was lower than the recommended value (median = 137.7 µg/L, 95% CI = 132.9 – 155.9, while non-pregnant women had UIC levels within the appropriate range (median = 190 ?g/L; 95% IC = 159.3-200.1. UIC was below 150 µg/L in 57% of the pregnant women.Conclusions : Although a larger sample is needed to consolidate these findings, these results raise concerns about the adequacy of the iodine supply of pregnant women in Brazil, especially considering the new determinations of the Brazilian government, which have recently reduced the concentrations of iodine in table salt to 15-45 mg/kg of salt. Arq Bras Endocrinol Metab. 2014;58(3:282-7
Full Text Available Background: Cognitive behavioral interventions consisting of brief counseling and the provision of self-help material designed for pregnancy have been documented as effective smoking cessation interventions for pregnant women. However, there is a need to understand how such interventions are perceived by the targeted group. Aim: To understand the cognitive, emotional, and behavioral responses of pregnant women to a clinic-based smoking cessation intervention. Methods: In-depth interviews with women attending four antenatal clinics in Cape Town, South Africa, who were exposed to a smoking intervention delivered by midwives and peer counselors. Women were purposively selected to represent a variation in smoking behavior. Thirteen women were interviewed at their first antenatal visit and 10 were followed up and reinterviewed later in their pregnancies. A content analysis approach was used, which resulted in categories and themes describing women's experiences, thoughts, and feelings about the intervention. Results: Five women quit, five had cut down, and three could not be traced for follow-up. All informants perceived the intervention positively. Four main themes captured the intervention's role in influencing women's smoking behavior. The process started with ‘understanding their reality,’ which led to ‘embracing change’ and ‘deciding to hold nothing back,’ which created a basis for ‘turning hopelessness into a feeling of competence.’Conclusion: The intervention succeeded in shifting women from feeling pessimistic about ever quitting to feeling encouraged to try and quit. Informants rated the social support they received very highly and expressed the need for the intervention to become a routine component of clinic services.
Full Text Available Objective: The purpose of this study was to determine the level of knowledge of folic acid supplementation amongst Iranian pregnant women.Materials and methods: We selected 322 women through simple randomized method in a cross section study. Data was gathered on the base of questionnaire and interview. Statistical analysis was performed using SPSS software. The value of p<0.05 was considered as significant level.Results: The obtained information revealed that 7.8% with high level of knowledge, 43.8% with intermediate level, 30.4% with low level knowledge, and 18% with no knowledge. Hospitals and health centers are two major sources for promoting popular awareness about folic acid. There is a significant relationship between the knowledge, education, employment, time of prenatal care beginning, age, gravidity, and sources of health information. The number of women with high level of knowledge was more among those with lower parity, higher level of education, employment, young age and looking for health information.Conclusion: Awareness of folic acid is low among Iranian women. The different strategies are required to elevate the knowledge about folic acid among the women in reproductive age and provide them with some information about the benefits of this supplement.
Full Text Available INTRODUCTION: Toxoplasmosis is one of the diseases comprising the TORCH [ Toxoplasma gondii , Rubella virus , Cytomegalovirus , Herpes simplex virus] infections . It is known to cause perinatal death if the organism is acquired during pregnancy . Toxoplasmosis during pregnancy can cause congenital infection which may result in mental retardation and blindness in the infant . The present study aimed to evaluate the seroprevalence of Toxoplasma gondii and it i s associated risk facto rs among the women with history of spontaneous abortion . MATERIALS & METHODS: A total of 60 women with past or present history of spontaneous abortion and another 60 pregnant women without any bad obstetric history as control attending our hospital were in cluded in the study . All the serum samples were tested for the presence of specific Toxoplasma IgM and IgG antibodies using the On Site Toxo IgG/IgM Rapid Test strip , a lateral flow chromatographic immunoassay . RESULTS: Total seroprevalence of Toxoplasma gondii in the study was 12 . 5% . Total seropositivity in women with history of spontaneous abortion was 12 ( 20% and 3 ( 5% among control group . More number of seropositivity was observed among women between 26 to 30 years ( 60% . Risk factor of having cat a s pet animal had greater association of getting toxoplasmosis . CONCLUSION: This study revealed that the seroprevalence of toxoplasmosis was significantly high in the study population than in control group . There should be routine screening for antenatal wo men with bad obstetric history .
Paula Sacha Frota Nogueira
Full Text Available INTRODUCTION: The clinical characteristics of women who conceive during leprosy and the association between leprosy and pregnancy are not well known. METHODS: This cross-sectional study included 49 pregnant or lactating women diagnosed with leprosy in 2011. RESULTS: The patients had a clinical dimorphous form of leprosy (44.9%, no physical incapacity at diagnosis (87.5%, and no complications in either the patient or infant (33.4%. In 36.3% of cases, leprosy symptoms were presented in the last trimester of pregnancy, and in 31.9% of patients were in the first trimester of lactation. CONCLUSIONS: The association between leprosy and pregnancy should be routinely investigated, particularly in endemic areas.
Paula Sacha Frota, Nogueira; Escolástica Rejane Ferreira, Moura; Andrezza Alves, Dias; Camila Félix, Américo; Lidiane Rebouças, Aguiar; Mayenne Myrcea Quintino Pereira, Valente.
Full Text Available INTRODUCTION: The clinical characteristics of women who conceive during leprosy and the association between leprosy and pregnancy are not well known. METHODS: This cross-sectional study included 49 pregnant or lactating women diagnosed with leprosy in 2011. RESULTS: The patients had a clinical dimo [...] rphous form of leprosy (44.9%), no physical incapacity at diagnosis (87.5%), and no complications in either the patient or infant (33.4%). In 36.3% of cases, leprosy symptoms were presented in the last trimester of pregnancy, and in 31.9% of patients were in the first trimester of lactation. CONCLUSIONS: The association between leprosy and pregnancy should be routinely investigated, particularly in endemic areas.
Full Text Available Introduction: “Geographic tongue” or benign migratory glossitis is a tongue disorder which causes pain and dysfunction and its persistence leads to cancer phobia. Based on some reports, hormones (especially female sex hormones are associated with geographic tongue development or exacerbation. Geographic tongue might be confused with lichen planus and candidiasis. The aim of this study was to evaluate the association of the lesion with pregnancy and its changes during each trimester. Materials and Methods: In this descriptive, analytical and cross-sectional study, 451 eligible cases were selected. After clinical examination and completion of questionnaires, if geographic tongue was diagnosed, photographs were taken and compared between the three trimesters. Data was analyzed with chi-squared test and Pearson’s correlation coefficient at a confidence interval of 95%. Results: The prevalence of geographic tongue in pregnant women was 36.8%. There were no significant relationships between the number of pregnancies, age and the frequency of the lesions. However, there was a significant relationship between the ectopic lesions and the fissured tongue (p value = 0.001 and also between the gestational age and geographic tongue lesions (p value = 0.043. The lesions were most prevalent in the second trimester, but in third trimester, prevalence of severs lesions decreased. Conclusions: Under the limitations of the present study, prevalence of geographic tongue in pregnant women was higher than previous reports in other communities. Severe lesions were more prevalent in the second trimester. Key words: Benign migratory glossitis, Hormones, Pregnancy.
Full Text Available Background: The purpose of this study was to explore health promoting lifestyles andrelated factors in pregnant women.Methods: This was a descriptive study using convenience sampling. Altogether, 172pregnant women were recruited from a medical center in southern Taiwan.Personal data was collected, and the instruments used included perceivedhealth status, self-efficacy of health behaviors, perception of family or peers’health-promoting behaviors, and Health Promoting Lifestyle Profile (HPLP?.Results: The results showed that the standardized total score of health promotinglifestyles was 66.88 (moderate level. The subscales of the HPLP ? indescending order of standardized scores were as follows: “interpersonal relationships,”“health responsibility,” “psychological wellness,” “nutrition,”“stress management” and “physical activity.” There were significant differencesin the total scores of the HPLP ? among subjects with different educationallevel, socioeconomic status, chronic diseases, exercise habits, lengthof sleep, and perceived health status. Both perception of health-promotingbehaviors among family (or peers and self-efficacy of health behaviors hadsignificantly positive relationships with health-promoting lifestyles.Perception of the family or peers’ health-promoting behaviors, self-efficacyof health behaviors, perceived health status and chronic diseases were thefour significant predictors of health-promoting lifestyles, accounting for62.4% of the variance.Conclusion: The findings of this study could be used as a reference for prenatal care,nursing education, and maternal / neonatal health policies.
Eighty five normal pregnant women were included in the study at the start of the second trimester. Two blood samples were taken during the second trimester and two blood samples during the third trimester. The height of all subjects was measured. The weights of the subjects were under iron-supplementation throughout the gestation period. Sixty four normal non-parentage women were included in the study to serve as controls. Iron status was assessed for the groups with following parameters, haemoglobin (Hb), packed corpuscular volume (PCV), red blood cells count, peripheral blood film, mean corpuscular volume (MCV), mean cell haemoglobin (MCH), Mean haemoglobin concentration (MCH C), serum iron (Si), total iron binding capacity (T IBC), serum transferrin saturation (Ts) and serum ferritin (Sf). No significant difference was observed in the mean haemoglobin concentrations but the PCV of the non-pregnant women was higher than that of the pregnant women at different stages of gestation (p<0.05). MCV, MCH and MCH C values of the non-pregnant women were lower than those of the of the pregnant at different stages of gestation (p<0.05). Serum iron and transferrin saturation of the non-pregnant women were higher than those of the pregnant women, this difference was statistically significant at weeks (16-18) and (22-24) (p<0.05). Serum ferritin of the non-pregnant women was higher than that of the pregnant women and decreased continuously during the pregnancy, but this decrease was not statistically significant. Iron deficiency anaemia was observed in both pregnant and non-pregnant women. The best parameter that could be used as a marker for iron deficiency is serum ferritin. Iron supplementation s corrected for haemoglobin but not for iron status, but more studies were needed to cover this issue using different parameters.(Author)
Sunita Bamanikar; Liew Kok Kee
Objectives: Pregnant women are more susceptible to periodontal disease like gingivitis. Periodontal disease may be associated with adverse pregnancy outcomes. There is no published literature on dental health in pregnant women in Brunei, Darussalam. The objective of this study was to assess women’s knowledge and attitude towards oral and dental health during pregnancy and to examine their self-care practices in relation to oral and dental health. This study was carried out at the maternal chi...
Fall, Aïssatou; Goulet , Lise; Vézina, Michel
The objectives of our study were to compare the prevalence of major depressive symptoms between subgroups of pregnant women: working women, women who had stopped working, housewives and students; and to identify risk factors for major depressive symptoms during pregnancy. The CES-D scale (Center for Epidemiological Studies Depression scale) was used to measure major depressive symptoms (CES-D score ?23) in 5337 pregnant women interviewed at 24–26 weeks of pregnancy. Multivariate logistic regr...
Gabriela Fernandes e Silva, Maíra Domingues Bernardes Silva, Leila Rangel da Silva, Inês Maria Meneses dos Santos
Full Text Available Objectives: to analyze the kinds of violence suffered in gestational period based on Ecological Model of Violence from Pan American Health Organization and to discuss the violence concept under point of view from pregnant women. Methods: descriptive study from qualitative approach conducted in a public maternity in Rio de Janeiro city. One hundred interviews were conducted with mothers in the Rooming-in Care. Results: among women who have suffered some kind of violence there is a greater proportion of physical aggression (67%, and the aggressor is, in most cases (33%, a person close to the woman. The victims did not seek a specialized help service (79%. The socio-demographic profile showed that the predominant age range was 20-29 years (56%, with a low level of schooling, less than six years of study, with a predominant family income of more than two minimum salaries and residents, most of them (27% from A.P.3.1 Méier. Conclusions: it’s important to ensure human rights and enhance the full care to women victims of violence. The existance of a regular training is essential to take care of these women, facing this violence phenomenon, offering then a careful, ethical and humane nursing.
Full Text Available The phytochemicals found in nine plants which are easily accessible to the women living in developing countries in particular is studied as the prevalence of diseases caused by lack of prenatal nutrients is high in these countries. Knowledge about these plants would help the expectant women to get the maximum prenatal nutrients like Folic acid, Iron, Vitamin B6, Zinc, Calcium, Choline and Alpha linoleic acid precursors needed to synthesize Omega 3 fats which are vital for the foetal growth and development. These plants are easily available and are affordable to the majority of poor women living in slums of the city dwellers and those who live in villages. Due to lack of knowledge, money, palatability issues, improper storage and consumption irregularities the expectant mothers in this category do not consume prescribed prenatal nutrients, affecting the mother and the foetus. Though prescribed prenatal nutrients are still very essential, same from the food sources have many benefits like they are from the complex mixture of many phytochemicals which act synergistically and provide known and unknown benefits to them. Apart from this, most of the plants listed here can be easily grown in pots or plots near their homes, manuring with kitchen wastes and without using chemical fertilizers or pesticides. Plants that provide all the prenatal nutrients and easily accessible for daily consumption by the pregnant women at an affordable cost in developing countries are Cowpea, Tomatoes, Turnip greens, Garlic, Wheat, Drumstick leaves, Cauliflower, purslane and Guava fruits.
Full Text Available Domestic violence is an important risk factor for pregnancy complications. The aim of this study is to determine the prevalence of domestic violence and its related factors in a population of pregnant women. A cross sectional study was done on 426 women who were attended to an obstetrics ward of a hospital in Iran. A 35 item questionnaire was completed by the respondents. The life time prevalence of domestic violence was 42% and it was 19.3% during pregnancy. There was no relation between socioeconomic status, women`s education and employment and age of marriage with domestic violence. Unemployment, addiction and alcohol use among husbands were related to domestic violence. Slapping and punching were the most common kinds of violent behavior. The prevalence of domestic violence even during pregnancy is high in Iran, so there is a need to increase the awareness of the community and empower the health workers and professionals in order to prevent and control this problem.
Bischoff, Anne Louise; Følsgaard, Nilofar Vahman; Carson, Charlotte Giwercman; Stokholm, Jakob; Pedersen, Louise; Holmberg, Maria; Bisgaard, Amalie; Birch, Sune; Tsai, Theodore F; Bisgaard, Hans
Pregnant women were suspected to be at particular risk when H1N1pnd09 influenza became pandemic in 2009. Our primary objective was to compare the immune responses conferred by MF59®-adjuvanted vaccine (Focetria®) in H1N1pnd09-naïve pregnant and non-pregnant women. The secondary aims were to compare influences of dose and adjuvant on the immune response.
Khoshdel, Abolfazl; Kheiri, Soleiman; Nasiri, Jafar; Tehran, Hoda Ahmari; Heidarian, Esfandiar
Background: Many pregnant Muslim women choose to fast during Ramadan every year worldwide. This study aimed to examine the effect of Ramadan fasting on serum leptin, neuropeptide Y and insulin in pregnant women and find whether fasting during pregnancy could have a negative effect on the health of mothers and fetuses.
E A Troshina
Full Text Available The aim of this study was estimate the influence of Iron Deficiency Anemia (IDA on efficiency of the iodine prophylaxis for pregnant women, and also to offer the optimal levels of daily iodine intake during pregnancy and lactation. Materials and methods: serum thyroid stimulating hormone (TSH, free thyroxin (fT4, AT-TPO concentrations, urine excretion of iodine, levels of hemoglobin (Hb, hematocrit (Ht, red blood cell (RBC, mean corpuscular hemoglobin (MCH, serum iron levels and serum ferritin were measured. The volume of thyroid gland was defined by ultrasonography. The pregnant women were divided into two groups: Group 1 (n = 111 – KI (200 micro# grams/day and Group 2 (n = 109 – KI (300 micrograms/day. Results: Median urinary iodine was 140,8 ?g/l. During pregnancy there was an authentic rising of a median urinary iodine to 259,6 ?g/l in group 2 (p = 0,0000 and in group 1 the iodine excretion in urine was more low than at a stage of screening and has compounded 96,9 ?g/l (p = 0,002. During lactation there was an insufficient concentration of iodide in urine in group 1 and in group 2 there were normal indexes of a median urinary iodine – 88,6 and 123,2?g/l in groups 1st and 2nd accordingly (p = 0,004. In the third trimester 21,5% of women had a latent deficiency of iron. Authentic correlation between indexes of an iron deficiency anemia and iodine deficiency has not been detected. Conclusion: The median level of urinary iodine indicate optimal iodine nutrition during pregnancy and lactation and the requirement of iodine is at least 300 ?g/day. In our research the negative influence of iron deficiency anemia on the efficiency of iodine prophylaxis during pregnancy has not been detected.
Proper metabolism of folates has a crucial role for body homeostasis. Folate metabolism regulates changing of amino acids (homocysteine and methionine), purine and pyrimidine synthesis and DNA methylation. These whole biochemical processes have significant influence on hematopoietic, cardiovascular and nervous system functions. The disturbances of folate cycle could result in chronic hypertension, coronary artery disease, higher risk of heart infarction, could promote cancers development, and psychic and neurodegenerative diseases. No less important is the connection with complications appearing in pregnant woman (recurrent miscarriages, preeclampsia, fetus hypotrophy intrauterine death, preterm placenta ablation, preterm delivery) and fetus defects (Down syndrome, spina bifida, encephalomeningocele, myelomeningocele). The complex process of folate metabolism requires adequate activity of many enzymes and presence of co-enzymes. A key enzyme in folate metabolism is methylenetetrahydrofolate reductase (MTHFR - methylenetetrahydrofolate reductase), and 677C>T polymorphism of MTHFR gene is connected with lower enzymatic activity In several researches it was indicated that 677C>T MTHFR polymorphism is an independent factor influencing homocysteine concentration in serum, and also folate concentration in serum and red blood cells. Nevertheless, it was also observed the correlation of 677C>T MTHFR polymorphism with Down syndrome, and neural tube defects appearance in fetus. In European populations frequency of mutated 677TT genotype ranges from a few to several percent. Women carriers of 677TT or 677CT MTHFR genotypes are exposed on folate metabolism disturbances and on the consequences of incorrect folate process during pregnancy Nowadays in this group of women folic acid supplementation is widely recommended. In the light of modern knowledge the attention was also focused on the importance of metafolin administration that omitted pathways of folic acid transformation after administration, and in pregnant women certainly is valuable complement of supplementation in this respect. PMID:23819405
Sensitivity to ionizing radiation is greater during intrauterine stages of development than at other stages in the life of the mammalian organism. For this reason, the NCRP recommends special care in patient selection in certain cases of diagnostic radiology and nuclear medicine diagnostic procedures. For women of child-bearing capacity, the physician requesting a radiological or nuclear medicine examination involving the lower abdominal or pelvic region should ascertain whether the patient is, or could be, pregnant. Further, the NCRP recommends that physicians tell their premenopausal patients that, if they are likely to have nuclear medicine studies or x-ray examinations of the lower abdomen, it is generally advisable that they not run a risk of pregnancy until two months after the studies are carried out. Modification of an examination for dose reduction is warranted only if it reasonably can be done without significant jeopardy to the medical care of the patient and/or her unborn child
Full Text Available Introduction: In Iran little attention has been paid to the important role of husband’s support in promoting maternal health. This study aimed to investigate the relationship between perceived social support from family in pregnant women and pregnancy-related factors. Methods: The study included 358 postpartum women in the second half of the year 2014 in Fatemiyeh Hospital in Shahroud, North East of Iran. The data collection instruments included Perceived Social Support - Family Scale (PSSFa. Results: Eleven (1.3% women had poor family support, 100 women (27.9% had moderate family support and 247 women (69% had good family support. There were no significant relationships between perceived support from family with mother’s BMI, family economic status and occupation of the mother, smoking and substance abuse by the mother, and husband’s education. But a significant relationship was found between mother’s score of family support and her age and education, so that mothers with high school diploma and higher education had scores which were significantly higher than the others. Also, women whose husbands were smoking or abused drug had lower support scores. The support had significant relationship with the number of pregnancies and pregnancy complications so that the more pregnancies a mother had, the lower the support was. Mothers with pregnancy complications also had lower support scores. Social support in unwanted pregnancies was significantly lower than wanted pregnancies..Conclusion: Family and social support is associated with pregnancy side effects and outcomes and in high-risk and unwanted pregnancies, it was lower.
Fernanda Campos, Machado; Dionéia Evangelista, Cesar; Amanda Vervloet Dutra Agostinho, Assis; Cláudio Galuppo, Diniz; Rosangela Almeida, Ribeiro.
Full Text Available The aim of this study was to use the fluorescence in situ hybridization (FISH) technique to test the hypothesis of qualitative and quantitative differences of 8 periodontopathogens between pregnant and non-pregnant women. This cross-sectional study included 20 pregnant women in their second trimeste [...] r of pregnancy and 20 non-pregnant women. Probing depth, bleeding on probing, clinical attachment level, and presence of calculus were recorded. Subgingival plaque samples were collected and the FISH technique identified the presence and numbers of Aggregatibacter actinomycetemcomitans, Tannerella forsythia, Campylobacter rectus, Porphyromonas gingivalis, Treponema denticola, Fusobacterium nucleatum, Prevotella intermedia and Prevotella nigrescens. The Mann-Whitney U-test was applied to compare the data between the two groups. The mean age, ethnicity, marital status, education, and economic level in both groups were similar. The clinical parameters showed no significant differences between pregnant and non-pregnant women. The numbers of subgingival periodontopathogens were not found to be significantly different between groups, despite the higher mean counts of P. intermedia in pregnant women. Colonization patterns of the different bacteria most commonly associated with periodontal disease were not different in the subgingival plaque of pregnant and non-pregnant women.
Ali, Nurshad; Blaszkewicz, Meinolf; Nahid, Abdullah Al; Rahman, Mustafizur; Degen, Gisela H.
The trichothecene mycotoxin deoxynivalenol (DON) is a contaminant of crops worldwide and known to cause adverse health effects in exposed animals and humans. A small survey reported the presence of DON in maize samples in Bangladesh, but these data are insufficient to assess human exposure, and also, biomonitoring data are still scarce. The present study applied biomarker analysis to investigate the DON exposure of pregnant women in Bangladesh. Urine samples were collected from pregnant women living in a rural (n = 32) and in a suburban (n = 22) area of the country. Urines were subjected to enzymatic hydrolysis of glucuronic acid conjugates and to immunoaffinity column clean-up prior to LC-MS/MS analysis of DON and its de-epoxy metabolite DOM-1. The limits of detection (LOD) for DON and DOM-1 in urine were 0.16 ng/mL and 0.10 ng/mL, respectively. DOM-1 was not detected in any of the urines, whilst DON was detectable in 52% of the samples at levels ranging from 0.18–7.16 ng/mL and a mean DON concentration of 0.86 ± 1.57 ng/mL or 2.14 ± 4.74 ng/mg creatinine. A significant difference in mean urinary DON levels was found between the rural (0.47 ± 0.73 ng/mL) and suburban (1.44 ± 2.20 ng/mL) cohort, which may be related to different food habits in the two cohorts. Analysis of food consumption data for the participants did not show significant correlations between their intake of typical staple foods and DON levels in urine. The biomarker concentrations found and published urinary excretion rates for DON were used to estimate daily mycotoxin intake in the cohort: the mean DON intake was 0.05 µg/kg b.w., and the maximum intake was 0.46 µg/kg b.w., values lower than the tolerable daily intake of 1 µg/kg b.w. These first results indicate a low dietary exposure of pregnant women in Bangladesh to DON. Nonetheless, further biomonitoring studies in children and in adult cohorts from other parts of the country are of interest to gain more insight into DON exposure in the population of Bangladesh. PMID:26404372
Ali, Nurshad; Blaszkewicz, Meinolf; Al Nahid, Abdullah; Rahman, Mustafizur; Degen, Gisela H
The trichothecene mycotoxin deoxynivalenol (DON) is a contaminant of crops worldwide and known to cause adverse health effects in exposed animals and humans. A small survey reported the presence of DON in maize samples in Bangladesh, but these data are insufficient to assess human exposure, and also, biomonitoring data are still scarce. The present study applied biomarker analysis to investigate the DON exposure of pregnant women in Bangladesh. Urine samples were collected from pregnant women living in a rural (n = 32) and in a suburban (n = 22) area of the country. Urines were subjected to enzymatic hydrolysis of glucuronic acid conjugates and to immunoaffinity column clean-up prior to LC-MS/MS analysis of DON and its de-epoxy metabolite DOM-1. The limits of detection (LOD) for DON and DOM-1 in urine were 0.16 ng/mL and 0.10 ng/mL, respectively. DOM-1 was not detected in any of the urines, whilst DON was detectable in 52% of the samples at levels ranging from 0.18-7.16 ng/mL and a mean DON concentration of 0.86 ± 1.57 ng/mL or 2.14 ± 4.74 ng/mg creatinine. A significant difference in mean urinary DON levels was found between the rural (0.47 ± 0.73 ng/mL) and suburban (1.44 ± 2.20 ng/mL) cohort, which may be related to different food habits in the two cohorts. Analysis of food consumption data for the participants did not show significant correlations between their intake of typical staple foods and DON levels in urine. The biomarker concentrations found and published urinary excretion rates for DON were used to estimate daily mycotoxin intake in the cohort: the mean DON intake was 0.05 µg/kg b.w., and the maximum intake was 0.46 µg/kg b.w., values lower than the tolerable daily intake of 1 µg/kg b.w. These first results indicate a low dietary exposure of pregnant women in Bangladesh to DON. Nonetheless, further biomonitoring studies in children and in adult cohorts from other parts of the country are of interest to gain more insight into DON exposure in the population of Bangladesh. PMID:26404372
Full Text Available The trichothecene mycotoxin deoxynivalenol (DON is a contaminant of crops worldwide and known to cause adverse health effects in exposed animals and humans. A small survey reported the presence of DON in maize samples in Bangladesh, but these data are insufficient to assess human exposure, and also, biomonitoring data are still scarce. The present study applied biomarker analysis to investigate the DON exposure of pregnant women in Bangladesh. Urine samples were collected from pregnant women living in a rural (n = 32 and in a suburban (n = 22 area of the country. Urines were subjected to enzymatic hydrolysis of glucuronic acid conjugates and to immunoaffinity column clean-up prior to LC-MS/MS analysis of DON and its de-epoxy metabolite DOM-1. The limits of detection (LOD for DON and DOM-1 in urine were 0.16 ng/mL and 0.10 ng/mL, respectively. DOM-1 was not detected in any of the urines, whilst DON was detectable in 52% of the samples at levels ranging from 0.18–7.16 ng/mL and a mean DON concentration of 0.86 ± 1.57 ng/mL or 2.14 ± 4.74 ng/mg creatinine. A significant difference in mean urinary DON levels was found between the rural (0.47 ± 0.73 ng/mL and suburban (1.44 ± 2.20 ng/mL cohort, which may be related to different food habits in the two cohorts. Analysis of food consumption data for the participants did not show significant correlations between their intake of typical staple foods and DON levels in urine. The biomarker concentrations found and published urinary excretion rates for DON were used to estimate daily mycotoxin intake in the cohort: the mean DON intake was 0.05 µg/kg b.w., and the maximum intake was 0.46 µg/kg b.w., values lower than the tolerable daily intake of 1 µg/kg b.w. These first results indicate a low dietary exposure of pregnant women in Bangladesh to DON. Nonetheless, further biomonitoring studies in children and in adult cohorts from other parts of the country are of interest to gain more insight into DON exposure in the population of Bangladesh.
Mortensen, Mary E., E-mail: MMortensen@cdc.gov [National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA (United States); Calafat, Antonia M.; Ye, Xiaoyun; Wong, Lee-Yang [National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA (United States); Wright, David J. [Westat, Inc. Rockville, MD (United States); Pirkle, James L. [National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA (United States); Merrill, Lori S. [Westat, Inc. Rockville, MD (United States); Moye, John [NCS Program Office, Eunice Kennedy Shriver National Institute for Child Health and Human Development, National Institutes for Health, Bethesda, MD (United States)
Environmental phenols are a group of chemicals with widespread uses in consumer and personal care products, food and beverage processing, and in pesticides. We assessed exposure to benzophenone-3, bisphenol A (BPA), triclosan, methyl- and propyl parabens, and 2,4- and 2,5-dichlorophenol or their precursors in 506 pregnant women enrolled in the National Children's Study (NCS) Vanguard Study. We measured the urinary concentrations of the target phenols by using online solid-phase extraction–isotope dilution high performance liquid chromatography–tandem mass spectrometry. NCS women results were compared to those of 524 similar-aged women in the National Health and Nutrition Examination Survey (NHANES) 2009–2010, and to 174 pregnant women in NHANES 2005–2010. In the NCS women, we found significant racial/ethnic differences (p<0.05) in regression adjusted mean concentrations of benzophenone-3, triclosan, 2,4- and 2,5-dichlorophenol, but not of BPA. Urinary 2,4- and 2,5-dichlorophenol concentrations were highly correlated (r=0.66, p<0.0001). Except for BPA and triclosan, adjusted mean concentrations were significantly different across the 7 study sites. Education was marginally significant for benzophenone-3, triclosan, propyl paraben, and 2,5-dichlorophenol. Urinary concentrations of target phenols in NCS pregnant women and U.S. women and pregnant women were similar. In NCS pregnant women, race/ethnicity and geographic location determined urinary concentrations of most phenols (except BPA), suggesting differential exposures. NCS Main Study protocols should collect urine biospecimens and information about exposures to environmental phenols. - Highlights: • Limited biomonitoring data are available in pregnant women. • Seven urinary phenols were measured in 506 third trimester women enrolled in the NCS. • Urine benzophenone-3, triclosan, 2,4- and 2,5-dichlorophenol differed by race/ethnicity. • Urinary concentrations of 2,4- and 2,5-dichlorophenol were highly correlated. • Exposure information can expand the utility of biospecimens in the NCS Main Study.
Thaysa Monteiro RAMOS
Full Text Available Objective: Mothers exert an important role in the stablishment of the dental care habits of their children and they are the major source from which infants acquire cariogenic microorganisms. Thus, the aim of this research was to assess the oral health conditions and oral hygiene habits of pregnant women of low socioeconomic status in the city of Aracaju-SE. Method: One hundred and seventy pregnant women were randomly selected to be interviewed in accordance with a structured questionnaire about oral health, dental hygiene and socio-economic status. The oral conditions were evaluated by the DMFT, IHO-S e SI index. Results: In regard to oral hygiene habits, 58% of the interviewed women brushed their teeth three times a day. The majority (98% made use of toothpaste but only 33% made use of the dental floss. The mean DMTF was 10.43 and the mean value of the IHO-S was 1.93. Nevertheless, the prevalence of the gingival bleeding was low (10.1%. Conclusion: The pregnant women presented poor oral health conditions and undesirable oral hygiene habits justifying the necessity of a primary dental health preventive approach with targeted measures directed at the pregnant women.
Hoglund Richard M
Full Text Available Abstract Background Pregnancy is associated with an increased risk of developing a malaria infection and a higher risk of developing severe malaria. The pharmacokinetic properties of many anti-malarials are also altered during pregnancy, often resulting in a decreased drug exposure. Piperaquine is a promising anti-malarial partner drug used in a fixed-dose combination with dihydroartemisinin. The aim of this study was to investigate the population pharmacokinetics of piperaquine in pregnant and non-pregnant Sudanese women with uncomplicated Plasmodium falciparum malaria. Method Symptomatic patients received a standard dose regimen of the fixed dose oral piperaquine-dihydroartemisinin combination treatment. Densely sampled plasma aliquots were collected and analysed using a previously described LC-MS/MS method. Data from 12 pregnant and 12 non-pregnant women were analysed using nonlinear mixed-effects modelling. A Monte Carlo Mapped Power (MCMP analysis was conducted based on a previously published study to evaluate the power of detecting covariates in this relatively small study. Results A three-compartment disposition model with a transit-absorption model described the observed data well. Body weight was added as an allometric function on all clearance and volume parameters. A statistically significant decrease in estimated terminal piperaquine half-life in pregnant compared with non-pregnant women was found, but there were no differences in post-hoc estimates of total piperaquine exposure. The MCMP analysis indicated a minimum of 13 pregnant and 13 non-pregnant women were required to identify pregnancy as a covariate on relevant pharmacokinetic parameters (80% power and p=0.05. Pregnancy was, therefore, evaluated as a categorical and continuous covariate (i.e. estimate gestational age in a full covariate approach. Using this approach pregnancy was not associated with any major change in piperaquine elimination clearance. However, a trend of increasing elimination clearance with increasing gestational age could be seen. Conclusions The population pharmacokinetic properties of piperaquine were well described by a three-compartment disposition model in pregnant and non-pregnant women with uncomplicated malaria. The modelling approach showed no major difference in piperaquine exposure between the two groups and data presented here do not warrant a dose adjustment in pregnancy in this vulnerable population.
Akhavan Amjadi, Marjan; Mojab, Faraz; Kamranpour, Seyedeh Bahareh
Itching is one of the most common skin symptoms. Generalized pruritus occurs in 1-8% of pregnant women. It can create unpleasant feeling for these women especially at nights. Most pregnant women avoid using synthetic drugs because of their side effects. Peppermint is a plant which has been used as a traditional drug in Iran. It decreases skin’s temperature. This study was done to determine the effects of peppermint oil on symptomatic treatment of pruritus in pregnant women attending to Rasoul...
Poston, Lucilla; Patel, Nashita
With the increasing prevalence of obesity, maternal obesity is now one of the most common high-risk obstetric conditions. Obesity and excessive gestational weight gain are important modifiable risk factors for maternal and neonatal morbidity and mortality. Maternal obesity, associated with neonatal adiposity and high birthweight, has been implicated in increased risk of childhood obesity. Considerable effort has been directed towards improving clinical outcomes by lifestyle change in pregnant obese women, but there is at present no evidence-based intervention of adequate efficacy which can be recommended. The focus has been on preventing excessive weight gain, but studies have lacked the power to address effects on clinical outcomes; therefore preventing clinical practice translation. Adequately powered intervention studies devised to reduce neonatal adiposity by improvement of maternal glucose homeostasis, are needed to inform the optimal dietary and/or physical activity regimen. PMID:25230591
Uchenna I., Eze; Adego E., Eferakeya; Azuka C., Oparah; Ehijie F., Enato.
Full Text Available Manejar las complicaciones médicas en el embarazo es un reto para los clínicos. Objetivos: Este estudio delineó algunos patrones de enfermedades y prescripciones en embarazadas que visitan una clínica prenatal en Nigeria. Se determinó una clasificación de riesgo de los medicamentos. Métodos: Se inve [...] stigaron los historiales médicos de 1200 mujeres embarazadas que visitaron las clínicas de preparto de tres centros en la ciudad de Benin , Nigeria. Los patrones de enfermedades se determinaron desde sus diagnósticos. Los patrones de prescripción se evaluaron utilizando los indicadores del a OMS y la clasificación de medicamentos de la Food and Drug Adminsitration de Estados Unidos según el riesgo para el feto. Resultados: Durante el periodo de revisión, se evaluaron 1897 prescripciones de las 1200 mujeres embarazadas que visitaron. Los resultados indicaron que la malaria con 554 (38%) fue la enfermedad más prevalente, seguida de las infeccione respiratorias altas (IRA) con 13% y enfermedades gastrointestinales (GI) con 12%. La media de medicamentos prescritos por visita fue de 3,0 y 2434 (43%) fueron prescritas en genéricos. Minerales/vitaminas, con 2396 (42%) fueron los medicamentos mas prescritos, y los antibióticos aparecieron en 502 (8,8%). De todos los medicamentos prescritos, 984 (17%) se incluían en la categoría de riesgo fetal C y 286 (5%) en la categoría D. Conclusión: Este estudio concluyó que entre las mujeres embarazadas, la malaria era la enfermedad más frecuente, seguida de las IRA y las GI. Los minerales y vitaminas seguidos el os antibióticos encabezaron l alista de medicamentos prescritos. La media de medicamentos por visita fue mucho mayor que los estándares recomendados por la OMS. La aparición de medicamentos contraindicados era baja. Abstract in english Managing medical complications in pregnancy is a challenge to clinicians. Objectives: This study profiled some disease and prescription patterns for pregnant women attending antenatal clinics (ANCs) in Nigeria. A risk classification of the medicines was also determined. Methods: Medical case files o [...] f 1,200 pregnant women attending antenatal clinics of 3 health facilities in Benin City, Nigeria were investigated. Disease pattern was determined from their diagnoses. The prescription pattern was assessed using WHO indicators, and the United States Food and Drug Administration classification of medicines according to risk to the foetus. Results: A total of 1,897 prescriptions of the 1,200 pregnant women attendees during the period under review were evaluated. Results indicated that malaria 554 (38%) was the most prevalent disease, followed by upper respiratory tract infections (URTIs, 13%) and gastrointestinal disturbances (GIT, 12%). The average number of drugs prescribed per encounter was found to be 3.0, and 2,434 (43%) of medicines were prescribed by generic name. Minerals/ Vitamins 2,396 (42%) were the most frequently prescribed medicines, and antibiotics occurred in 502 (8.8%) of the total medicines. Of all medicines prescribed, 984 (17%) were included in the foetal risk category C and 286 (5%) in category D. Conclusion: The study concluded that malaria fever occurred most frequently followed by URTIs and GIT disturbances among the pregnant women. Minerals, vitamins and to a less extent anti-malarials topped the list of the prescribed medicines. The average number of medicines per encounter was much higher than WHO standards. The occurrence of contraindicated medicines was low.
Full Text Available
Background and Objectives: Pregnancy is a critical period during which good maternal nutrition plays a key role influencing the health of both mother and child. The present study aimed at determining the intakes of energy and related factors in pregnant women.
Methods: In this cross-sectional study 1036 pregnant women were selected from health centers of urban areas in Qom. Personal interviews using the questionnaire of 24 -hour dietary recall were carried out to elicit information. Calorie intake efficacy was calculated based on nutrient substance intake. The data analysis was performed by SPSS software program. X2 test was used to determine the significance of differences (p<0/05.
Results: Calorie intake of 50% of subjects was adequate. The majority of pregnant women who had reported higher intake of energy were illiterate (%56.4 and house holders (%51/1? and in the third trimester (%58.8 There was a significant difference between calorie intake, occupation, level of education and stage of pregnancy. The mean of energy from oil and fat was higher than that of other food groups.
Conclusion: The findings of the present study suggest that the nutritional education is a component of programs targeted at working women and low income families.
Wagey Freddy Wagey
Full Text Available Objectives: Pregnancy is a vulnerable condition to all kinds of "stress", resulting in changes of physiological and metabolic functions. This research aims to determine effect of exercise during pregnancy in increasing enzymatic antioxidant marked by increase of superoxide dismutase (SOD, gluthation peroxidase (GSHPx, and catalase (CAT levels. Methods: Randomized pre and posttest control group design was employed in this study. A number of 66 pregnant women were recruited in this study and grouped into two groups, i.e 30 of them as control group and the rest as treatment group. Pregnancy exercise was performed to all 36 pregnant women from 20 weeks gestation on treatment group. The exercise was performed in the morning for about 30 minutes, twice a weeks. On the other hand, daily activities was sugested for control group. Student’s t-test was then applied to determine the mean different of treatment and control group with 5 % of significant value. Results: This study reveals that there were significantly higher increase of (superoxide dismutase (SOD, gluthation peroxidase (GSHPx, and catalse (CAT levels of treatment group compare to control group. These enzymatic antioxidant increase among these two group were around 1.36 mg/gHb for SOD; 1.14 IU/gHb for GSHPx; and 0.97 IU/gHb for CAT, (p < 0.05. Clinical outcomes, such as strengten of pelvic muscle and quality of life of treatment group were significantly better compared to control group (p < 0.05. Conclusions: This means that exercise during pregnancy ages of 20 weeks increase enzymatic antioxidant levels SOD, GSHPx, and CAT higher compare to control group without exercise.
Wagey Freddy Wagey
Full Text Available Objectives: Pregnancy is a vulnerable condition to all kinds of "stress", resulting in changes of physiological and metabolic functions. This research aims to determine effect of exercise during pregnancy in increasing enzymatic antioxidant marked by increase of superoxide dismutase (SOD, gluthation peroxidase (GSHPx, and catalase (CAT levels. Methods: Randomized pre and posttest control group design was employed in this study. A number of 66 pregnant women were recruited in this study and grouped into two groups, i.e 30 of them as control group and the rest as treatment group. Pregnancy exercise was performed to all 36 pregnant women from 20 weeks gestation on treatment group. The exercise was performed in the morning for about 30 minutes, twice a weeks. On the other hand, daily activities was sugested for control group. Student’s t-test was then applied to determine the mean different of treatment and control group with 5 % of significant value. Results: This study reveals that there were significantly higher increase of (superoxide dismutase (SOD, gluthation peroxidase (GSHPx, and catalse (CAT levels of treatment group compare to control group. These enzymatic antioxidant increase among these two group were around 1.36 mg/gHb for SOD; 1.14 IU/gHb for GSHPx; and 0.97 IU/gHb for CAT, (p < 0.05. Clinical outcomes, such as strengten of pelvic muscle and quality of life of treatment group were significantly better compared to control group (p < 0.05. Conclusions: This means that exercise during pregnancy ages of 20 weeks increase enzymatic antioxidant levels SOD, GSHPx, and CAT higher compare to control group without exercise.
Full Text Available Introduction: Social support is considered the interaction between the person and environment, which reduces stressors, covers the effects of stress and consequently protects individuals from the harmful effects of stressful situations. This study aimed to determine social support in pregnant women and its relationship with the rate of pregnant women ' s perceived stress at health centers of Tabriz in 2012-13. Methods: This cross–sectional study was carried out on 450 pregnant women selected through cluster sampling. Data collection tools consisted of a demographic questionnaire, interpersonal support evaluation list (ISEL and perceived stress questionnaire (PSS that were completed in an interview. The range of obtainable score for social support and perceived stress was 0-90 and 0-30, respectively. Descriptive and analytical statistics including Pearson and Independent t-test were used for analyzing the data. Results: The mean score of social support and perceived stress in pregnant women was 96.6 (14.6, and 11.5 (5.5, respectively .The women with favorable social support had significantly less stress than the women with unfavorable social support. Conclusion: The study finding showed that the rate of social support in highly stressful women is significantly less than low-stress mothers. Therefore, considering adverse effects of the stress on pregnancy outcomes, some strategies should be designed and implemented in order to strengthen and improve the social support for pregnant women so that it can reduce the rate of pregnant women’s stress.
Gustavo Pereira Fraga
Full Text Available OBJETIVOS: avaliar os fatores indicativos (parâmetros clínicos e índices de gravidade fisiológicos e anatômicos da evolução materna e fetal entre gestantes vítimas de trauma abdominal submetidas à laparotomia e discutir as particularidades do atendimento nesta situação. MÉTODOS: análise retrospectiva dos prontuários de 245 mulheres com trauma abdominal e tratamento operatório, atendidas entre 1990 e 2002. Foram identificadas 13 gestantes com lesão abdominal submetidas à laparotomia. Para registro e análise estatística dos dados foram utilizados o protocolo Epi-Info 6.04 e o teste exato de Fisher, com intervalo de confiança de 95%. Foram relacionados com a mortalidade fetal: escore na escala de coma de Glasgow, pressão arterial sistólica, índices de trauma (RTS, ATI, ISS e lesão uterina. RESULTADOS: a idade variou de 13 a 34 anos (média de 22,5. Seis mulheres (46,2% estavam no terceiro trimestre de gestação. O trauma penetrante correspondeu a 53,8% das lesões e em seis dessas pacientes o mecanismo de trauma foi ferimento por projétil de arma de fogo. Três pacientes tiveram lesões uterinas, associadas com óbito fetal. Não houve óbito materno e a mortalidade fetal foi de 30,7%. Não houve associação entre os índices de trauma e a mortalidade materna e fetal. A lesão uterina foi o único fator preditivo de risco para perda fetal (p=0,014. CONCLUSÕES: apesar da casuística pequena e de se tratar de estudo retrospectivo de gestantes com trauma grave, os achados deste estudo mostram que não há indicadores com boa acurácia para indicação da evolução materna e fetal.PURPOSE: to evaluate the predictors (clinical findings and physiological and anatomical scores of the maternal and fetal outcomes among pregnant women victims of abdominal trauma who were submitted to laparotomy and to discuss particularities of assessment in this situation. METHODS: retrospective analysis of the medical records of 245 women with abdominal trauma and surgical treatment, from 1990 to 2002. Thirteen pregnant women with abdominal injury were identified. All cases were registered in the Epi-Info 6.04 protocol and data were analyzed statistically by the Fisher exact test, with confidence interval of 95%. RESULTS: ages ranged from 13 to 34 years (mean of 22.5. Six women (46.2% were in the third trimester of pregnancy. Penetrating trauma accounted for 53.8% of injuries and in six of these patients the mechanism of trauma was gunshot wounds. Three patients had uterine injuries associated with fetal death. There were no maternal deaths and fetal mortality was 30.7%. The use of trauma scores was not associated with maternal and fetal mortality. Uterine injury was the only predictive risk factor for fetal loss (p=0.014. CONCLUSIONS: this is a retrospective study analyzing a small number of pregnant women victims of severe trauma. However, the results show that there are no predictive accuracy scores to evaluate maternal and fetal outcomes.
Jones, N.; Oliver, K; Jones, Y; Haines, A.; Crook, D.
OBJECTIVE: To investigate asymptomatic vagino-rectal carriage of group B streptococcus (GBS) in pregnant women. METHODS: Women in the final trimester of pregnancy were recruited. A single vagino-rectal swab was taken, with consent, for culture of GBS. Two microbiological methods for isolation of GBS from vagino-rectal swabs were compared. The distribution of capsular serotypes of the GBS identified was determined. Epidemiological data for a subset (n = 167) of the pregnant women participating...
Aynur Saruhan; Ahsen Sirin; Oya Kavlak; Aytül Hadimli; Emre Yanikkerem; Sezer Er Güneri; Emine Sen
Background: Health practices in pregnancy could be defined as the activities affecting the health of mothers, fetus andnewborns.Objective: To determine knowledge requirements and health practices of adolescent pregnant women.Design: Descriptive studyMethodology: The population is composed of adolescents women applying to pregnancy polyclinics of state hospitals forroutine antenatal colsultation in Izmir, Ayd?n and Manisa provinces. 156 pregnant women between 13-21 years of age whoaccepted par...
Mbizvo Elizabeth M; Hussain Akhtar; Uriyo Jacqueline; Msuya Sia E; Jeansson Stig; Sam Noel E; Stray-Pedersen Babill
Abstract Objectives To determine the prevalence of sexually transmitted infections (STIs) and other reproductive tract infections (RTIs) among pregnant women in Moshi, Tanzania and to compare the occurrence of STIs/RTIs among human immunodeficiency virus (HIV)-infected and uninfected women. Methods Pregnant women in their 3rd trimester (N = 2654) were recruited from two primary health care clinics between June 2002 and March 2004. They were interviewed, examined and genital and blood samples ...
Nierop, Ada; Wirtz, Petra H.; Bratsikas, Aliki; Zimmermann, Roland; Ehlert, Ulrike
Sixty healthy pregnant women (aged 21-35 years), including 30 pregnant women at the beginning of second trimester and 30 women at the beginning of third trimester underwent a psychosocial stress test. Physiological (salivary free cortisol levels, salivary alpha-amylase levels) and psychological (perceived stress, mood, anxiety) responses to standardized psychosocial stress have been brought in association with psychosocial resources (self-efficacy and daily uplifts). Predictions revealed that...
Gul Kiziltan; Efsun Karabudak; Gorkem Tuncay; Filiz Avsar; Piril Tuncay; Onur Mungan; Pinar Meral
OBJECTIVES To determine the effects of Ramadan fasting on dietary intakes, nutritional status and biochemical parameters of Turkish pregnant women. METHODS We carried out this study at Dr. Zekai Tahir Burak Women's Health Care and Research Hospital, Ankara, Turkey from October 15th to November 13th 2004. Forty-nine fasting group and 49 non-fasting group (control group) voluntarily enrolled for the study. We analyzed the blood biochemical parameters of pregnant women and obtained...
Munjoma, Marshall W
Objectives: To investigate the use of lactobacillus as a simple tool for the diagnosis of bacterial vaginosis (BV) using wet mounts in pregnant women and to assess the positive predictive value of absence of lactobacillus for Human Immunodeficiency Virus Type-1 (HIV-1) infection. Methods: 409 pregnant women were enrolled from three randomly selected clinics around Harare. The women underwent clinical examination during which a speculum-aided high vaginal swab was obtained and tested for BV ...
Massougbodji Achille; Mévo Blaise; Borgella Sophie; Gbaguidi Gildas; Fievet Nadine; Huynh Bich-Tram; Deloron Philippe; Cot Michel
Abstract Background It is generally agreed that in high transmission areas, pregnant women have acquired a partial immunity to malaria and when infected they present few or no symptoms. However, longitudinal cohort studies investigating the clinical presentation of malaria infection in pregnant women in stable endemic areas are lacking, and the few studies exploring this issue are unconclusive. Methods A prospective cohort of women followed monthly during pregnancy was conducted in three rura...
Kuo, Caroline; Schonbrun, Yael Chatav; Zlotnick, Caron; Bates, Nicole; RalitsaTodorova,; Chien-Wen Kao, Jennifer; JOHNSON, JENNIFER
Little is known about treatment for pregnant and postpartum women with co-occurring substance use and depression. Funded by the National Institute of Drug Abuse, we conducted three focus groups with 18 pregnant and postpartum women in 2011 at an urban substance use treatment clinic. A semi-structured discussion guide probed for factors impacting treatment outcomes and needs. Data were analyzed using grounded theory. Women identified motivational, family, friend, romantic, and agency character...
Diab Tayseer E; Salih Yasir; Abbaker Ameer O; Rayis Duria A; Adam Ishag
Abstract Background The increasing prevalence of obesity in young women is a major public health concern. Few data are available concerning the epidemiology of malnutrition especially obesity among pregnant women in the developing countries. A cross sectional study was conducted at Khartoum hospital during February-April 2008, to investigate prevalence of underweight, obesity, and to identify contemporary socio-demographic predictors for obesity among term pregnant women in Khartoum Hospital,...
Ima O. Williams
Full Text Available The vitamin A status of 101 pregnant women attending clinic at the University of Calabar Teaching Hospital (UCTH, Calabar, Nigeria was assessed based on 24 h dietary recall, serum retinol concentration, history of night blindness, physical appearance and clinical eye signs. The study revealed that the mean dietary vitamin A intake of the respondents (2645.31 ±188.91 ?g RE and their mean serum retinol concentration (31.18 ±2.94 ?g dL-1 were significantly (p<0.05 higher than the FAO/WHO recommended intake and cutoff level for VAD. No case of night blindness, physical signs and symptoms, or clinical eye signs attributable to VAD was observed. There was a significant (p<0.01 correlation between the amount of 24 h vitamin A intake of the women and their serum retinol concentration (r = 0.31. Also, women who had above 50% of their vitamin A intake from provitamin A sources had a significantly (p<0.05 lower serum retinol concentration (23.10 ±21.12 ?g dL-1 than those who had above 50% intake from preformed sources (49.54 ±42.63 ?g dL-1 and those with about equal intake from both sources (55.75 ±30.80 ?g dL-1. There was a significant (p<0.05 and steady decline in serum retinol concentration in the women from the first trimester (37.79 ±6.65 ?g dL-1, through the second trimester (35.12 ±4.72 ?g dL-1, to the third trimester (21.54 ±1.46 ?g dL-1 of pregnancy.
Full Text Available Background:Syphilis is an infectious disease caused by Treponema pallidum and transmitted via sexual contact, infected discharge and blood as well as vertical transmission. It causes various impacts on women during pregnancy and their newborns which results in various complications. Thus, screening of syphilis is routinely performed during pregnancy. Choosing to perform a specific screening test is based on the prevalence of the disease in the target population which needs adequate information in this regard. The aim of the present study was to determine the prevalence of syphilis among pregnant women in Shiraz, South-west of Iran. Materials and Methods: in this 15 month prospective study, 1100 pregnant women aged between 15 – 42 years, referred to University affiliated hospital in shiraz, Iran were included Blood samples were obtained from all of our study population for performing RPR test. FTA-ABS serologic test was carried out on positive cases of RPR test. Results:15 suspicious cases with weakly positive RPR test were detected but in all of them FTA-ABS tests were negative.Conclusions: The prevalence and incidence of syphilis was low in our area which may be due to variable reasons, such as reduction in the rate of unsafe and unprotected sex, improving knowledge, and adequate health care services. More studies are still needed to decide whether syphilis screening is beneficial in our area and should be considered as a routine test in pregnancy
Bischoff, Anne Louise
Pregnant women experience increased influenza related morbidity and mortality during seasonal influenza epidemics, and even graver outcomes during influenza pandemics. Thus, even though the huge amount of data on clinical efficacy and effectiveness of influenza vaccine in pregnant women, there is limited information on the details of the immunological responses to influenza immunization in pregnant versus non-pregnant. We had the unique opportunity to study the H1N1pnd09 vaccination of pregnant ...
Lei, Yajing; Fang, Lizheng; Akash, Muhammad Sajid Hamid; Rehman, Kanwal; Liu, Zhiming; Shi, Weixing; Chen, Shuqing
Aflatoxin M1 (AFM1 ) is a main cause of hepatocarcenogenoma in Chinese population. Measurement of aflatoxin exposure in human may help in providing clear evidence for the exposure of specific environmental pollutants in certain population. "One child policy" in China offered parents more careful to choose safe food during pregnancy, but no reports published on the efficacy of their endeavor. In present study, we aimed to assess the exposure of AFM1 in Chinese pregnant women. The urine samples were collected from 600 volunteers from Zhejiang province, China and the urinary concentration of AFM1 was measured using ELISA kit. AFM1 was detected in 84% of the pregnant women. The geometric mean and 95th percentile concentration of AFM1 in pregnant women were 50.3 ng/L and 633.5 ng/L, respectively. Our results point out that pregnant women especially are at the high risk of exposure to AFM1 . Our results also indicate that although "one child policy" offered parents to pay more attention for the selection of safe food, but detection of AFM1 in urine of pregnant women indicate that more foods containing AFM1 still need to be detected. Highest exposure of AFM1 in pregnant women indicates that awareness campaigns must be started especially in the rural areas of China regarding the possible hazardous effects of AFM1 exposure in pregnant women. PMID:24102482
Jenn Leiferman; Elizabeth Sinatra; Jennifer Huberty
Aim: The primary aim of the project was to conduct focus groups with pregnant women to examine their perceptions on patient and health care provider (HCP) communication during prenatal visits pertaining to health behavioral change. In particular, to determine what types of communication facilitate or prevent patient engagement and adherence to certain health behaviors related to smoking cessation, engagement in physical activity, healthy eating and healthy weight gain, ...
Rasmussen, Mette; Heitmann, Berit Lilienthal; Tønnesen, Hanne
Smoking is considered the most important preventable risk factor in relation to the development of complications during pregnancy and delivery. The aim of this study was to evaluate the effectiveness of an intensive 6-week gold standard programme (GSP) on pregnant women in real life.
The aim of this dissertation was to determine quantitatively prostaglandin-F in the plasma of pregnant women in order to obtain further knowledge on changes in PG-F during pregnancy, in particular during the last three months. The plasma of women with clinically normal pregnancies was taken. Prior to radioimmunoassay the plasma was extracted (separation of PG from other plasma components) and chromatography carried out (group separation of PG). The efficiency of this process, as measured by the recovery rate of 3H-PGF, lies between 60.99% and 93.01% for extraction and between 80.58% and 92.16% for chromatography. The plasma was extracted and analysed chromatographically for the assay. The radioimmunoassay was carried out according to the procedure recommended by the manufacturer. A calibration curve was produced without difficulty. The results of the examination of plasma samples were unsatisfactory because of the low sensitivity of the assay; PG-F values of the same order were obtained for all weeks of pregnancy. (orig./MG)
Francine, Ntoumi; Damien, Bakoua; Anna, Fesser; Michael, Kombo; Christevy, Vouvoungui J; Felix, Koukouikila-Koussounda
Malaria in pregnancy remains a serious public health problem in the Republic of Congo despite the implementation of intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp-SP) in 2006. The aim of this cross-sectional study was to characterize Plasmodium falciparum infections and determine possible risk factors in pregnant Congolese women attending an antenatal clinic in a periurban area of southern Brazzaville. This study was conducted from March 2012 to December 2013 in a site where several years ago, high malaria resistance to SP was reported. Pregnant women were enrolled during antenatal visits and the number of received IPTp-SP doses was recorded as well as individual sociodemographic data. Peripheral blood was collected and P. falciparum infection was checked by microscopy and by PCR targeting P. falciparum merozoite surface protein gene (msp2). Haemoglobin concentration was measured and P. falciparum positive samples were typed for msp2 allelic diversity. A total of 363 pregnant women were recruited. The prevalence of asymptomatic P. falciparum infection was 7% and 19% by microscopy and by PCR, respectively. More than one half (51.5%) of the pregnant women were anaemic. Multivariate analysis indicated that P. falciparum infection was associated with anaemia. It was also observed that women who have received IPTp-SP have significantly lower prevalence of infection. The administration of IPTp-SP did not influence the multiplicity of infection (MOI). This first study investigating asymptomatic malaria infection on pregnant women of the Republic of Congo shows that P. falciparum infections were clearly associated with maternal anaemia, and use of IPTp-SP reduced the risk of carrying asymptomatic infections. PMID:26477849
Shan Elahi; Zaib Hussain
Problem Statement. Thyroid gland in women undergoes functional changes during pregnancy. A few studies have described such changes in pregnant women residing in iodine deficient areas. Objective. To document these changes in pregnant women residing in Lahore, a low iodine intake urban area of Pakistan. Patients and Methods. In 254 pregnant women, data of FT4, FT3, and TSH during the first and subsequent trimesters were obtained and compared with those of 110 nonpregnant women. These hormones ...
Aníta Guðný Gústavsdóttir 1975
Objectives: One of the most critical periods of iodine deficiency is pregnancy.The study had two aims: 1) To assess iodine status of pregnant women in a population changing from a high to lower consumption of milk and fish, which are important sources of dietary iodine. 2) To assess food choice among pregnant women and compliance to the Icelandic food based dietary guidelines (FBDG). Subjects/Methods: Subjects were randomly selected pregnant women (19-43 years-old, n=162). A validated F...
Windsor, R. A.; Warner, K E; Cutter, G. R.
Estimates of the cost effectiveness and cost benefit of health promotion-health education methods for pregnant smokers designed to increase birth weight are not available. This paper presents the results of a cost-effectiveness analysis from a recently completed randomized trial to evaluate the effectiveness of self-help smoking cessation methods for pregnant women in public health maternity clinics. The study population--309 pregnant smokers from 3 prenatal clinics--were randomly assigned, d...
Full Text Available There is an increased prevalence of maternal substance abuse during pregnancy in younger women in all socioeconomic classes and races. Our aim was to determine the prevalence and correlates of self-reported substance abuse among pregnant women and obstetric complications or neonatal outcomes in Iran. This retrospective cohort study is covering a five year period on medical records of pregnant women attending the maternity unit of four major hospitals (Mahdieh, Taleghani, Imam Hossein and Akbarabadi Hospitals. Women who reported using opium, heroin, crack, cannabis or methamphetamine were compared with women with no reported history of drug abuse for obstetric complications and prenatal morbidity and neonatal mortality. From 100,620 deliveries substance abuse was recorded for 519 women giving a prevalence of 0.5%. Opium was the most prevalent substance abused followed by crack (a mix of heroin and amphetamines. The exposed group had significantly more obstetric complications including preterm low birth weight and postpartum hemorrhage than the non-exposed group. The exposed group had significantly worse prenatal outcomes including more admissions to intensive care unit and higher infant mortality than the non-exposed group. None of the women in the exposed group was on methadone treatment at time of delivery. Risks of maternal and neonatal complications were increased in substance using pregnant women, especially preterm birth and low birth weight. We recommend a multidisciplinary team to provide methadone maintenance therapy for substance using pregnant women and urinary screen of all pregnant women presenting to hospital.
Full Text Available Abstract Background Physical activity may reduce the risk of adverse maternal outcomes, yet there are very few studies that have examined the correlates of exercise amongst obese women during pregnancy. We examined which relevant sociodemographic, obstetric, and health behaviour variables and pregnancy symptoms were associated with exercise in a small sample of obese pregnant women. Methods This was a secondary analysis using data from an exercise intervention for the prevention of gestational diabetes in obese pregnant women. Using the Pregnancy Physical Activity Questionnaire (PPAQ, 50 obese pregnant women were classified as "Exercisers" if they achieved ?900 kcal/wk of exercise and "Non-Exercisers" if they did not meet this criterion. Analyses examined which relevant variables were associated with exercise status at 12, 20, 28 and 36 weeks gestation. Results Obese pregnant women with a history of miscarriage; who had children living at home; who had a lower pre-pregnancy weight; reported no nausea and vomiting; and who had no lower back pain, were those women who were most likely to have exercised in early pregnancy. Exercise in late pregnancy was most common among tertiary educated women. Conclusions Offering greater support to women from disadvantaged backgrounds and closely monitoring women who report persistent nausea and vomiting or lower back pain in early pregnancy may be important. The findings may be particularly useful for other interventions aimed at reducing or controlling weight gain in obese pregnant women.
Twite, Kabange E.; Daumerie, Chantal; Wallemacq, Pierre; Donnen, Philippe; Kalenga, Muenze K.; Robert, Annie
Background: Despite notable progress in the fight against iodine deficiency disorders in the Democratic Republic of Congo, a recent study has shown that pregnant women in Lubumbashi were still iodine deficient. Our objective was to assess thyroid function in this population. Methods: In a cross-sectional study conducted in maternity units from three different socioeconomic areas in Lubumbashi, serum thyrotropin, free thyroxine, thyroglobulin, and thyroperoxidase antibodies were measured in 225 pregnant women attending antenatal visits, in 75 women who recently delivered, and in 75 nonpregnant controls. The outcome was the prevalence of thyroid dysfunction. Results: Median values in pregnant women, women who recently delivered, and nonpregnant women were 1.80, 2.80, and 1.54?mIU/L for thyrotropin (pthyroid dysfunction in pregnant women, in women who recently delivered, and in nonpregnant women was 31%, 8%, and 20% for isolated hypothyroxinemia (pthyroid dysfunction in pregnant women of Lubumbashi, and this high prevalence is associated with iodine deficiency. To prevent obstetrical adverse outcomes and neurological damage in children, iodine supplementation is needed before conception or in early pregnancy in Lubumbashi. PMID:23957235
Westerneng, Myrte; de Cock, Paul; Spelten, Evelien R; Honig, Adriaan; Hutton, Eileen K
The 10-item version of the Pregnancy-Related Anxiety Questionnaire-Revised was developed based on a sample of nulliparous women. Whether this measure is also a valuable tool for future research on pregnancy-specific anxiety is unclear. Our study tested for invariance of this measure across nulliparous women and parous women by using a dataset of 6004 women pregnant up to 35 weeks. Results showed that whereas the factor structure of the 10-item version of the Pregnancy-Related Anxiety Questionnaire-Revised was noninvariant, removing item 8 from the measure created a measure with invariant factor loadings that can be used for all pregnant women. PMID:24058121
In facilities where workers are exposed to ionizing radiation, a system of radiation protection is implemented which is ultimately based on a balancing of the risks and benefits to the uses of radiation involved. More restrictive dose limits are set for members of the public than for workers and these have been applied also to conceptus.There are many different industries and practices that involve the use of ionizing radiation and the potential exposure of female workers at fertility age. The radiation sources and levels of exposure may vary significantly in different industries, such as those associated with the nuclear fuel cycle (where the workforce is mostly male), industrial radiography, diagnostic and therapeutic medical applications (where the number of female workers may be greater than males) and others.The International Commission on Radiological Protection (ICRP) and the International Atomic Energy Association (IAEA) in its Basic Safety Standards (BSS) recommend to regard the conceptus as a member of the public when considering the protection of female workers who are pregnant. There is a requirement that women should be informed of the importance of early notification of pregnancy.In 2001, the ICRP in its Publication 88 published biokinetic and dosimetric models for the calculation of doses to the conceptus from intakes by the mother. Several internal scenarios were considered, which include acute and chronic intakes by inhalation and ingestion for female workers and members of the public. For acute exposures, intakes were taken to occur at 2.5 years and 6 months before conception, at the time of conception, and at the end of weeks 5, 10, 15, 25 and 35 of the pregnancy.In 2005, the ICRP in its Publication 95 published biokinetic and dosimetric models for the calculation of doses to the infant from intakes by the breasfeeding mother.This work examines the significance of pregnant and breastfeeding women work with radioactive materials on the potential dose to their conceptus or children. The calculations are based on the data from ICRP Publications 88and 95.
Full Text Available Group B Streptococcus (GBS is the most common cause of life-threatening infection in neonates. Guidelines from CDC recommend universal screening of pregnant women for rectovaginal GBS colonization. The objective of this study was to compare the performance of a combined enrichment/PCR based method targeting the atr gene in relation to culture using enrichment with selective broth medium (standard method to identify the presence of GBS in pregnant women. Rectovaginal GBS samples from women at ?36 weeks of pregnancy were obtained with a swab and analyzed by the two methods. A total of 89 samples were evaluated. The prevalence of positive results for GBS detection was considerable higher when assessed by the combined enrichment/PCR method than with the standard method (35.9% versus 22.5%, respectively. The results demonstrated that the use of selective enrichment broth followed by PCR targeting the atr gene is a highly sensitive, specific and accurate test for GBS screening in pregnant women, allowing the detection of the bacteria even in lightly colonized patients. This PCR methodology may provide a useful diagnostic tool for GBS detection and contributes for a more accurate and effective intrapartum antibiotic and lower newborn mortality and morbidity.
F.M., Munari; F., De-Paris; G.D., Salton; P.S, Lora; P, Giovanella; A.B.M.P, Machado; L.S., Laybauer; K.R.P., Oliveira; C, Ferri; J.L.S., Silveira; C.C.F.C, Laurino; R.M., Xavier; A.L, Barth; S, Echeverrigaray; J.P., Laurino.
Full Text Available Group B Streptococcus (GBS) is the most common cause of life-threatening infection in neonates. Guidelines from CDC recommend universal screening of pregnant women for rectovaginal GBS colonization. The objective of this study was to compare the performance of a combined enrichment/PCR based method [...] targeting the atr gene in relation to culture using enrichment with selective broth medium (standard method) to identify the presence of GBS in pregnant women. Rectovaginal GBS samples from women at ?36 weeks of pregnancy were obtained with a swab and analyzed by the two methods. A total of 89 samples were evaluated. The prevalence of positive results for GBS detection was considerable higher when assessed by the combined enrichment/PCR method than with the standard method (35.9% versus 22.5%, respectively). The results demonstrated that the use of selective enrichment broth followed by PCR targeting the atr gene is a highly sensitive, specific and accurate test for GBS screening in pregnant women, allowing the detection of the bacteria even in lightly colonized patients. This PCR methodology may provide a useful diagnostic tool for GBS detection and contributes for a more accurate and effective intrapartum antibiotic and lower newborn mortality and morbidity.
Kihara, J H; Kutima, H L; Ouma, J; Churcher, T S; Changoma, J M; Mwalisetso, M A; French, M D; Mwandawiro, C S
Generally, women residing in areas endemic for urinary schistosomiasis may suffer from female genital schistosomiasis which is acquired during childhood. The objective of this cross-sectional study was to estimate the prevalence and intensity of infection of Schistosoma haematobium in women of reproductive age (16-45 years) and to investigate whether S. haematobium had any effect on kidney function. A total of 394 women of known pregnancy status (158 pregnant and 236 non-pregnant) were recruited from five villages (known for their high prevalence of infection of S. haematobium) in Kwale County. Serum samples were analysed to determine levels of urea and creatinine as proxy indicators of kidney function. Data revealed that pregnant women did not, on average, have a higher prevalence or intensity of infection of urinary schistosomiasis than non-pregnant women. During pregnancy, the level of prevalence and intensity of infection of S. haematobium was highest in the first trimester (0-13 weeks), dropped in the second trimester (14-26 weeks) and rose again in the third trimester (27-40 weeks). In addition, 24.8% of women were infected with hookworm, while none were diagnosed with malaria parasites. Of 250 samples analysed for serum urea and creatinine, none had significant levels of pathology, either in pregnant or non-pregnant women. Despite World Health Organization (WHO) recommendations that pregnant women should be treated with praziquantel after the first trimester, in practice this has not been the case in many countries, including Kenya. In view of this, healthcare providers should be informed to consider treatment of pregnant women infected with schistosomiasis during antenatal visits and whenever there is mass drug administration as recommended by the WHO. PMID:24103656
Hien, Vu Thi Thu; Lam, Nguyen Thi; Skeaff, C Murray; Todd, Joanne; McLean, Judy M; Green, Timothy J
Vitamin D insufficiency during pregnancy has been associated with a number of adverse outcomes for both mother and child. Vitamin D insufficiency has been well described in many populations of both pregnant and non-pregnant women of childbearing age, but there is a lack of data on women living in South-East Asia. We measured plasma 25-hydroxyvitamin D in a representative sample of pregnant (n=64) and non-pregnant (n=477) women (15-49 years) living in Hanoi City (n=270) and rural Hai Duong Province (n=271) in northern Vietnam. Mean 25-hydroxyvitamin D (95% confidence interval) concentration was 81 (79, 84)nmolL(-1) . Mean 25-hydroxyvitamin D concentration differed between urban and rural (78 vs. 85nmolL(-1) ; P=0.016), farming and non-farming (89 vs. 77nmolL(-1) ; P<0.001) but not pregnant and non-pregnant or older vs. younger women. Only one woman had a 25-hydroxyvitamin D less than 25nmolL(-1) , a concentration indicative of vitamin D deficiency. Of the women, 7% and 48% of the women were vitamin D insufficient based on cut-offs for plasma 25-hydroxyvitamin D of 50 and 75nmolL(-1) , respectively. Mean plasma 25-hydroxyvitamin D concentrations of these Vietnamese women were much higher than those reported in other studies of pregnant and non-pregnant women in the region. PMID:22117931
Amber M. Holbrook; Kaltenbach, Karol A.
Women in substance abuse programs have high rates of smoking. Pregnancy represents a unique opportunity for intervention, but few data exist to guide tailoring of effective interventions. In this study, 44 pregnant and 47 nonpregnant opioid-dependent women enrolled in comprehensive substance abuse treatment received a 6-week smoking cessation intervention based on the 5A's counseling model. The number of daily cigarettes decreased by 49% for pregnant patients and 32% for nonpregnant patients ...
Pandey, Shanta; Lin, Yuan; Collier-Tenison, Shannon; Bodden, Jamie
Approximately 10 million pregnant women around the world develop night blindness annually. In India, one in 11 pregnant women suffers from night blindness. This study used a nationally representative sample of 35,248 women from India between the ages of 15 and 49 who had given birth in the past five years to understand the effect of women's…
de Moura, Edilene Lins; Praça, Neide de Souza
This descriptive study with a qualitative approach was motivated by the high number of HIV positive children caused by perinatal transmission. The aim of this study was to identify HIV-infected pregnant women's expectations and actions concerning the pregnancy and the fetus. The sample consisted of 14 HIV-infected, asymptomatic pregnant women, in their third month, who were aware of their condition before getting pregnant. An interview was carried out from 2001 to 2002 in order to collect data. The Collective Subject Discourse Method was adopted for data analysis. It was observed that the pregnant women had similar expectations concerning motherhood. They got used to pregnancy and believed their baby would be HIV negative and that treatment would be effective. There is a need to implement counseling about women's health with a focus on perinatal HIV/aids transmission. PMID:16926998
Full Text Available Maternal mortality in childbirth in developing countries is still high. The study describes the qualitative methods used to examine the knowledge, attitude, beliefs and behaviour related to nutrition and nutritional supplementation of pregnant women. The role of village midwives and cadres’ in relation to nutrition education resulted in improving nutritional behaviour of pregnant women to some extent, but poverty and culture restricted the ability of pregnant women to access better food. The study shows that the position of pregnant woman is low within the hierarchy of both the health care system and the power structures of the broader community. Husbands, mothers-in-law, village midwives, cadres and village leaders all have more power in determining nutrition during pregnancy. However, some women tried to eat better and more nutritious food in secret, thereby subverting culture and the authority of husbands and mothers-in-law.
Full Text Available Introduction: the Consensus Conference of the American College ofChestSurgeons and the American Society of Critical Care Medicine in 1992, definesthe systemic inflammatory response syndrome (SIRS. In pregnantwomen, a seriesof physiological and anatomical changes. These changes SIRS denote by definition,being only physiological parameters in a pregnant woman with variation accordingto gestational age. The aim of this study is to perform a diagnostic evaluation of thedefinition of SIRS in critically ill obstetric patient, taking into account the parametersfound in two cohorts of patients.Methodology: we performed a multicenter comparative diagnostic study of twocohorts: a retrospective cohort of patients admitted to two intensive care units inthe city of Cartagena, Colombia, with a diagnosis ofsepsis of any origin, which werecompared with healthy pregnantpatients without septic focus in prenatal care in order toestimateappropriate cutoff for the definition of SIRS in pregnant women.Results: in developing this study we found that the cut-off points at 12400 cell/mm3 for leukocyte count, heart rate greater than 105 per minute and respiratory rate of20 per minute showed the best statistical behavior. With regard to the definition ofSIRS ConsensusConference of the American College of Chest Surgeons and the AmericanSociety of Critical Care Medicine in 1992, the only variation was found within thecutoff for heart rate, where 105 beats per minute, was show the best sensitivity andspecificity.Conclusión: the current criteria to define SIRS in pregnant women do not seem to beadequate according to the results of this study.RESUMEN:Introducción: en la Conferencia de Consenso del Colegio Americano de Cirujanos delTórax y de la Sociedad Americana de Medicina Crítica en 1992, se define el Síndromede Respuesta Inflamatoria Sistémica (SRIS. En la mujer gestante ocurren una seriede cambios fisiológicos y anatómicos. Estos cambios denotarían por su definición SRIS,siendo solamente parámetros fisiológicos en una mujer gestante con variación según suedad gestacional. El objetivo del presente trabajo es realizar una evaluación diagnósticade la definición de SRIS en la paciente obstétrica críticamente enferma, teniendo encuenta, los parámetros encontrados en dos cohortes de pacientes.Metodología: se realiza un estudio diagnóstico comparativo multicéntrico, de doscohortes; una cohorte retrospectiva de pacientes, ingresadas a dos unidades decuidados intensivos, en la ciudad de Cartagena, Colombia, con el diagnóstico de sepsisde cualquier origen, que se compararon con pacientes embarazadas sanas sin focoséptico en control prenatal, con el fin de estimar puntos de corte adecuados para ladefinición de SRIS en la embarazada.Resultados: al desarrollar este estudio encontramos que los puntos de corteestablecidos en 12400 cell/mm3 para el conteo leucocitario, frecuencia cardiaca mayorde 105 por minuto y frecuencia respiratoria mayor de 20 por minuto mostraron el mejorcomportamiento estadístico. Con respecto a la definición de SRIS de la conferencia deConsenso del Colegio Americano de Cirujanos del Tórax y de la Sociedad Americanade Medicina Crítica en 1992, la única variación encontrada corresponde al punto decorte para frecuencia cardiaca, donde 105 latidos por minuto, resultó mostrar la mejorsensibilidad y especificidad.Conclusión: los criterios actuales para definir SRIS, en la mujer gestante, no parecenser los más adecuados de acuerdo a los resultados de este estudio.
N.C. Iriemenam, A.O. Dosunmu, W.A. Oyibo & A.F. Fagbenro-Beyioku
Full Text Available Background & objectives: Little information exists on the compliance of pregnant women to malaria managementin malaria endemic countries. This study was designed to access knowledge, attitude, perception and homemanagement of malaria among consenting pregnant women attending antenatal care (ANC clinic.Methods: In total, 350 pregnant women were randomly recruited during their ANC Clinic in Lagos. Structuredquestionnaires were administered in a two-stages research design; first during their early months of ANC visitand the second approximately 1–2 months before delivery. Information on occupation, parity, symptoms used torecognise malaria, treatment sources, control measures, knowledge factors, anti-vector measures, health-seekingpractices, malaria parasitaemia and packed cell volume (PCV were recorded.Results: The results revealed that 78.9% of the pregnant women identified infected mosquitoes as the cause ofmalaria while 86% of the pregnant women identified stagnant water as its breeding sites. Knowledge of thebenefit of insecticide-treated mosquito bednets was less prominent as most of the selected subjects decried itshigh market price. Our data also showed that educational programme targeted on potential mothers is beneficial.Overall, 27.4% (96/350 of the pregnant women had peripheral malaria infection with 88.5% (85/96 of theparasite positive women infected with Plasmodium falciparum and 11.5% (11/96 with P. malariae. PCV rangedfrom 20–40% (median 33.9% with 25.7% (90/350 of the pregnant women being anaemic with PCV <33%. Wefound an association between malaria infection and occupation, and this association was not influenced byparity.Interpretation & conclusion: Our findings revealed that improvement in knowledge and education of women ofchild-bearing age has an influential impact on malaria control
Full Text Available ntroduction: The establishment of National Integrated Health System in Uruguay from 2007 led to changes in the financing of the Collective Health Care Institutions (IAMC. They charge the National Health Fund (FONASA for their partners from social security (SS a health fee consists of: a A risk-adjusted capita (94%b A component for compliance with performance (6%, depending on the fulfillment of three goals of care. Goal 1 is a component of the child under 1 year and a component of the pregnant woman. For both components were established institutional baseline (July 2007-September 2008 in the control patients in both age groups. This motif COMPLIANCE quarterly reports with a fee of $48/user FONASA/month for average baseline compliment. Las for children and pregnant women were monitored for IAMC CUDAM 64% and 59% respectively.This institution has 42,000 users, 95% derived from SS, featuring 45 births, 585 children <1 year and 405 pregnant women tested monthly.Objectives: Evaluate two years (July-September 2010:a The mean percentages of compliance for children and pregnant CUDAM with medical controlb Relationship between income through the FONASA insitucional for goal 1 and children and pregnant women in medical management during the quarter.Methods: a retrospective study of children and pregnant women with medical control CUDAM. In turn, each target has 6 indicators (N: children, F: females. Child: N1 and N2: derivation and acquisition of the newborn, N3: controls as a guideline, N4: current vaccination, N5: ultrasound hip and pregnant, N6: accreditation in good feeding practices for infants and young children and pregnant women. Pregnant woman: M1 controls as a guideline, M2: leaf perinatal information system, M3: HIV and VDRL performed, M4: uptake in 1 st quarter, M5 and M6: dental checkup during pregnancy and postpartum.Results: The mean percentages of compliance for children and pregnant women increased to 92% (164 additional children and 88% (117 additional pregnant respectively. Insitucional monthly income for the goal 1 was $1,915,200 (US$1 = $20.Average income/month was $1,637 and $2,364 per child and pregnant women respectively. We conclude that the target incentive payment of 1 allowed to significantly improve the indicators of child and maternal control of CUDAM.
Shopova, E; Dimitrov, A; Nikolov, A
Data of etiology characteristics of uroinfections with pregnant women are presented treated at University Hospital of Obstetrics and Gynecology "Maichin dom" in three periods. Gram negative species of microorganisms (E. coli, proteus, Klebsiella) are the agens of uroinfections in 95.4% of cases in the period 1988/89. After 10-year period gram (-) are the uroinfection in 66.1% of the cases. The growing etiologycal importance of Gram positive species of microorganisms (S. aureus, Enterococcus, GBS) is 33,9% in the period 1997/98 and it is preserved in june 2001/may 2003 too. In cases of long lasting hospitalization or after repeated treatment with antibiotics the probability grows that the agents of uroinfections be polyresistant strains. In the period june 2001/may 2003 in 7% of the cases polyresistant E. coli are isolated, in 2.6% MRSaureus, in 7.6% Ampicillin - R Enterococcus spp. That suggest exact identification of the agen and therapy according to sensitivity to antibiotics. PMID:15341251
Ramli, Remsen Maizan; Jaafar, M. S.; Ismail, N. E.; Saltani, Hend A. A.; Ahmad, A. L.; Bermakai, M. Yahaya
The purpose of this research is to study the fetal head circumference (HC) biometry for local population. Retrospective study was selected, done at Hospital Pulau Pinang and 5551 files of pregnant women were collected. The HC mean values of this study (HCmean) was compared with other published studies to see whether there was any difference between the various populations in the world. Comparison of means, regression analysis and paired sample t-test in SPSS software version 11.5 were used in the analysis. A total of 9874 HC data (mm) were recorded for gestational age (GA) of 12 to 41 weeks. The HC growth rate in second trimester (11.32 mm/week) has decreased to nearly half than in third trimester (5.53 mm/week). The HCmean was found to be highly significant difference (SD) than other 9 studies and only lower than HC values of USA, UK and Zimbabwe populations. The HC values of German show close similarity with HCmean. From 45 comparisons done, more than three-quarter of the comparisons resulted as SD (37) compared to insignificant differences (8). Consequently, each country should have their own standard HC of fetus biometry of the various gestations for their own population.
Marcela Peres Castilho-Pelloso; Dina Lúcia Morais Falavigna; Ana Lúcia Falavigna-Guilherme
OBJECTIVE: To determine the prevalence of reagent serology for suspected acute toxoplasmosis in pregnant women and to describe clinical, laboratory and therapeutic profiles of mothers and their children. METHODS: A retrospective study was conducted with IgM-anti-Toxoplasma gondii-reagent pregnant women and their children who attended the public health system in the state of Paraná, Southern Brazil, from January 2001 to December 2003. Information were obtained from clinical, laboratory (ELISA ...
Rankin Judith; McParlin Catherine; Robson Stephen C; Bush Judith; Weir Zoe; Bell Ruth
Abstract Background Whilst there has been increasing research interest in interventions which promote physical activity during pregnancy few studies have yielded detailed insights into the views and experiences of overweight and obese pregnant women themselves. The qualitative study described in this paper aimed to: (i) explore the views and experiences of overweight and obese pregnant women; and (ii) inform interventions which could promote the adoption of physical activity during pregnancy....
Allopregnanolone is a neuroactive steroid measurable in peripheral circulation. The aim of the present study was to investigate the presence and the possible changes in serum allopregnanolone and progesterone levels in pregnant women during gestation, at delivery, and in patients with chronic hypertension, with or without superimposed preeclampsia. We also evaluated allopregnanolone in cord blood. Three groups of pregnant women were studied: 1) healthy controls followed longitudinally through...
Cook, A. C.; Gilbert, R.; W Buffolano; Zufferey, J.; Petersen, E.; Jenum, P. A.; Foulon, W.; Semprini, A. E.; Dunn, D T
OBJECTIVE: To determine the odds ratio and population attributable fraction associated with food and environmental risk factors for acute toxoplasmosis in pregnancy. DESIGN: Case-control study. SETTING: Six large European cities. PARTICIPANTS: Pregnant women with acute infection (cases) detected by seroconversion or positive for anti-Toxoplasma gondii IgM were compared with pregnant women seronegative for toxoplasma (controls). MAIN OUTCOME MEASURES: Odds ratios for acute infection adjusted f...
Tefre de Renzy-Martin, Katrine; Frederiksen, Hanne; Christensen, Jeppe Hagstrup; Boye Kyhl, Henriette; Andersson, Anna-Maria; Husby, Steffen; Barington, Torben; Main, Katharina Maria; Jensen, Tina Kold
Many phthalates, parabens and phenols are suspected to have endocrine disrupting properties in humans. They are found in consumer products, including food wrapping, cosmetics and building materials. The foetus is vulnerable and exposure to these chemicals is of particular concern for pregnant women. We therefore studied current exposure to several commonly used phthalates, parabens and phenols in 200 healthy, pregnant Danish women. A total of 200 spot urine samples were collected between weeks 8...
HemahAndiappan; NongyaoSawangjareon; Si LayKhaing; Cristina CSalibay; Mary Mae MCheung; Julieta ZDungca
Toxoplasma gondii, is one of the infectious agents of congenital TORCH infections, causes severe clinical outcomes in fetus and newborns. Nevertheless this life-threatening parasitic disease is preventable by simple preventive measures related to lifestyle during pregnancy. We aim to study on the knowledge about toxoplasmosis and practices that prevents this infection among the pregnant women. Total of 2598 pregnant women from Malaysia, Philippines, and Thailand were randomly surveyed to dete...
Santacruz, Arlette; Collado, María del Carmen; García Valdés, L.; Segura, M. T.; Martín Lagos, J. A.; Anjos, T.; Martí Romero, M.; López, R.M.; Florido, J.; Campoy, Cristina; Sanz, Yolanda
Obesity is associated with complications during pregnancy and increased health risks in the newborn. The objective of the present study was to establish possible relationships between gut microbiota, body weight, weight gain and biochemical parameters in pregnant women. Fifty pregnant women were classified according to their BMI in normal-weight (n 34) and overweight (n 16) groups. Gut microbiota composition was analysed by quantitative real-time PCR in faeces and biochemical parameters in pl...
Mbada, Chidozie E; Adebayo, Olubukayomi E.; Adeyemi, Adebanjo B.; Olujide O. Arije; Dada, Olumide O.; Olabisi A. Akinwande; Awotidebe, Taofeek O.; Ibidun A. Alonge
Background. Engagement in physical exercise in pregnancy is hamstrung by safety concerns, skepticism about usefulness, and limited individualized prescription guidelines. This study assessed knowledge and attitude of pregnant women towards antenatal exercises (ANEx). Methods. The cross-sectional study recruited 189 pregnant women from six selected antenatal clinics in Ile-Ife, South-West, Nigeria. Data were obtained on maternal characteristics, knowledge, and attitude towards ANEx. Results. R...
Pregnant women at risk for preeclampsia may benefit from the positive effects of exercise, but they may be unlikely to adhere to an exercise program. A randomized trial was conducted with 124 sedentary pregnant women to compare the effects of walking exercise to a stretching exercise on adherence and on the preeclampsia risk factors of heart rate (HR), blood pressure, and weight gain. Walkers exercised less than stretchers both overall and as pregnancy advanced. HR and blood pressure were low...
Mehta, S; Spiegelman, D; Aboud, S; Giovannucci, E L; Msamanga, G I; Hertzmark, E; Mugusi, F M; Hunter, D J; Fawzi, W W
There is limited published research examining lipid-soluble vitamins in human immunodeficiency virus (HIV)-infected pregnant women, particularly in resource-limited settings. This is an observational analysis of 1078 HIV-infected pregnant women enrolled in a trial of vitamin supplementation in Tanzania. Baseline data on sociodemographic and anthropometric characteristics, clinical signs and symptoms, and laboratory parameters were used to identify correlates of low plasma vitamin A (
Ismaeel, Ayad Ghany; Hamead, Nur Gaylan
The statistic of World Health Organization shows at one year about 287000 women died most of them during and following pregnancy and childbirth in Africa and south Asia. This paper suggests system for serving pregnant women using open source based on Android technology, the proposed system works based on mobile GIS to select closest care centre or hospital maternity on Google map for the pregnant woman, which completed an online registration by sending SMS via GPRS network (...
Justyna Krzepota; Ewa Putek-Szel?g
introduction and objective. Teaching pregnant women behaviours connected with care for one’s health condition and a healthy lifestyle is crucial in perinatal care. Desired health behaviours, including nutritional habits, play an important role in the health of the mother, as well as the proper development of the foetus. The aim of the presented study was to analyse the subjective assessment of nutritional habits in the light of general health behaviours of pregnant women. materials and ...
Serra-Casas, Elisa; Menéndez, Clara; Dobaño, Carlota; Bardají, Azucena; Quintó, Llorenç; Ordi, Jaume; Sigaúque, Betuel; Cisteró, Pau; Mandomando, Inacio; Alonso, Pedro L.; Mayor, Alfredo
Pregnant women are susceptible to Plasmodium falciparum parasites that sequester in the placenta. The massive accumulation of infected erythrocytes in the placenta has been suggested to trigger the deleterious effects of malaria in pregnant women and their offspring. The risk of malaria is also high during the postpartum period, although mechanisms underlying this susceptibility are not known. Here, we aimed to identify host factors contributing to the risk of postpartum infections and to det...
Mona Abdullah Almushait; Hanem Abdullah Mohammed; Dai Abdullah Al-Harthy; Ashwaq Mohamed Abdullah
This study aimed to assess the prevalence of urinary tract infection (UTI) in pregnant women, to identify infectious agents causing the infection, and to explore relationship of specific socio–cultural factors with UTI. This study was conducted at the antenatal clinic of Abha General Hospital, Saudi Arabia from September 2012 to January 2013 on 402 pregnant Saudi women. Midstream urine sample was obtained. A urine analysis test and culture were done as well as socio-demographic data sheet was...
Kim, Euy Hyuk; Kim, In Kyu; Kwon, Ja Young; KIM, SANG WUN; Park, Yong Won
In the present study, we examined the relationship between average fish consumption, as well as the type of fish consumed and levels of mercury in the blood of pregnant women. We also performed follow-up studies to determine if blood mercury levels were decreased after counseling and prenatal education. To examine these potential relationships, pregnant women were divided into two groups: a study group was educated to restrict fish intake, whereas a control group did not receive any prenatal ...
Sornsrivichai Vosasit; Songwathana Praneed; Chongsuvivatwong Virasakdi; Liabsuetrakul Tippawan; Sukchan Phnom; Kuning Metta
Abstract Background The deep south of Thailand is an area which has been affected by violence since 2004, yet the concurrent coverage of antenatal care has remained at over 90%. Our study aimed to describe the prevalence of nutrient inadequacy among pregnant women who attended antenatal care clinics in hospitals in the study area and assess factors associated with nutrient inadequacy. Methods Pregnant women from four participating hospitals located in lower southern Thailand were surveyed dur...
Kedir, Haji; Berhane, Yemane; Worku, Alemayehu
Background. Iodine deficiency in pregnancy is a worldwide problem. This study aimed to assess prevalence and predictors of subclinical iodine deficiency among pregnant women in Haramaya district, eastern Ethiopia. Methods. A cross-sectional, community-based study was conducted on 435 pregnant women existing in ten randomly selected rural kebeles (kebele is the smallest administrative unit in Ethiopia). Data on the study subjects' background characteristics, dietary habits, and gynecological/o...
Singh Sarman; Gupta Richa; Gupta Swati
Abstract Background Estimating the seroprevalence of HIV in a low risk population such as pregnant women provides essential information for an effective implementation of AIDS control programmes, and also for the monitoring of HIV spread within a country. Very few studies are available from north India showing the current trend in HIV prevalence in the antenatal population;which led us to carry outthis study at a tertiary care hospital in north India Methods Blood samples from pregnant women ...
Faisal Anwar; Mudjajanto, Eddy S.; Drajat Martianto; Hakimi Hakimi
Previous studies have revealed that several factors influenced the relatively low success of iron supplementation for pregnant women. The factors included poor distribution, low coverage and compliance, as well as low absorption. The aim of this study is to measure the iron status of pregnant women after consuming crackers containing fish powder and iron-folate. This study was carried out in the Purworejo district (Central Java) from February through October 2002. Using a randomized controlle...
Wilson, Nana O.; Ceesay, Fatou K.; Obed, Samuel A.; Adjei, Andrew A.; Gyasi, Richard K; Rodney, Patricia; Ndjakani, Yassa; Anderson, Winston A.; Naomi W. Lucchi; Stiles, Jonathan K
The effectiveness of intermittent preventive treatment during pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) against malaria and anemia is unclear because of the spread of SP-resistant Plasmodium falciparum. This study evaluates the effectiveness of IPTp-SP among pregnant women attending the antenatal clinic at Korle-Bu Teaching Hospital in Accra, Ghana. A cross-sectional study comparing malaria and anemia prevalence among pregnant women using IPTp-SP with non-IPTp-SP users was conducted ...
Koepke, Ruth; Kahn, Danielle; Petit, Ashley B; Schauer, Stephanie L; Hopfensperger, Daniel J; Conway, James H; Davis, Jeffrey P
On February 22, 2013, the Advisory Committee on Immunization Practices (ACIP) revised recommendations for vaccination of pregnant women to recommend tetanus-diphtheria-acellular pertussis vaccine (Tdap) during every pregnancy, optimally at 27-36 weeks of gestation, to prevent pertussis among their newborns. Since 2004, influenza vaccination has been recommended for pregnant women in any trimester to prevent influenza and associated complications for mother and newborn. To evaluate vaccination of pregnant women in Wisconsin after the 2013 Tdap recommendation, health insurance claims data for approximately 49% of Wisconsin births were analyzed. The percentage of women who received Tdap during pregnancy increased from 13.8% of women delivering during January 2013 (63.1% of whom received Tdap 2-13 weeks before delivery) to 51.0% of women delivering during March 2014 (90.9% of whom received Tdap 2-13 weeks before delivery). Among women delivering during November 2013-March 2014, 49.4% had received influenza vaccine during pregnancy. After the 2013 recommendation, Tdap vaccination among pregnant women increased but plateaued at rates similar to influenza vaccination rates. Prenatal care providers should implement, evaluate, and improve Tdap and influenza vaccination programs, and strongly recommend that pregnant patients receive these vaccines to prevent severe illness and complications among mothers and infants. PMID:26182193
Full Text Available Previous studies have revealed that several factors influenced the relatively low success of iron supplementation for pregnant women. The factors included poor distribution, low coverage and compliance, as well as low absorption. The aim of this study is to measure the iron status of pregnant women after consuming crackers containing fish powder and iron-folate. This study was carried out in the Purworejo district (Central Java from February through October 2002. Using a randomized controlled trial (RCT design, 70 pregnant women in their second-third month of pregnancy were recruited, and divided into two groups. Ten women dropped out during the study. The first group consisted of 28 women were given protein – iron enriched crackers (PIEC group, while the second group of 32 women were given iron–enriched crackers (IEC group for a total of 12 weeks. The results showed that the hemoglobin (Hb levels and serum transferrin receptors (sTfR of both groups were increased. Serum ferritins (SF of both groups were decreased. At the end of the study, the increase in Hb and sTfR levels between the two groups were significantly different, while the decrease in SF was not significantly different. Animal protein from fish powder tended to improve absorption of non-heme iron among pregnant women, resulting in improved Hb and sTfR levels. (Med J Indones 2003; 12: 243-6Keywords: pregnant women, anemia, iron deficiency, high protein crackers
Yahia Z Gad
Full Text Available Background/Aim: Hepatitis E virus (HEV is a major public health problem in the developing countries. HEV infection in pregnant women is more common and fatal in the third trimester. The present study was designed to determine the seroprevalence of subclinical HEV infection in asymptomatic pregnant women. Materials and Methods: A total of 116 asymptomatic pregnant women divided into group 1, including 56 pregnant women with hepatitis C virus (HCV-positive serology and group 2, including 60 pregnant women with negative HCV serology were included in this study. The prevalence of anti-HEV antibodies and anti-HCV was determined by an enzyme-linked immunosorbent assay (ELISA kit. Results : The o verall prevalence of anti-HEV IgG was highly significant among pregnant women with chronic HCV infection [40/56 (71.42%] than in pregnant women free from chronic HCV infection [28/60 (46.7%] (P = 0.006. Chronic HCV infection in pregnant women appeared to be a risk factor associated with HEV IgG seropositivity (OR = 2.86, CI = 1.24-6.6 . The seropositivity of anti-HEV IgG was significantly high in rural areas than in urban areas (62.5% versus 37.5% in group 1 and (78.58% versus 21.42% in group 2 (P = 0.15 (OR = 2.2, CI = 0.65-7.7. A significant decrease in albumin (P = 0.047 and increase in bilirubin (P = 0.025, ALT (P = 0.032 and AST (P = 0.044 in pregnant women with positive HCV and IgG anti-HEV than in the second group with negative HCV serology was noted. Conclusions : The seroprevalence of anti-HEV IgG in pregnant women is high in Egypt, especially in the rural areas. With chronic HCV coinfection, marked increase in anti-HEV IgG seropositivity and significant worsening of the biochemical liver indices were noted. Increased public awareness about sound hygienic measures for a lower prevalence of HEV is strongly advised. The need for HEV vaccination for those at risk, especially pregnant ladies, should be considered.
Full Text Available Toxoplasma gondii, is one of the infectious agents of congenital TORCH infections, causes severe clinical outcomes in fetus and newborns. Nevertheless this life-threatening parasitic disease is preventable by simple preventive measures related to lifestyle during pregnancy. We aim to study on the knowledge about toxoplasmosis and practices that prevents this infection among the pregnant women. Total of 2,598 pregnant women from Malaysia, Philippines and Thailand were randomly surveyed to determine the knowledge and their practices on Toxoplasma infection. The questionnaire covered respondents’ general information and knowledge on plausible risks factors, symptoms, timing of infection, prevention knowledge and preventive behavior regarding Toxoplasma infection. Majority of these pregnant women were in their age group of 20-29 years (50.9%, completed secondary level of education (51.7%, in their second trimester of pregnancies (38.1%, non parous (36.6% and had no history of abortion (90.4. Based on this survey, only 11% of these pregnant women had read, heard or seen information regarding toxoplasmosis and 3.5% of them were aware of being tested for the infection. A small percentage of these pregnant women knew that T. gondii were shed in the feces of infected cats (19.4% and sometimes found in the raw or undercooked meat (11.0%. There was 16.1% of responding women knew that toxoplasmosis is caused by an infection. Demographic profiles such as age group, level of education, pregnancy term and number of children of the pregnant women showed significant association with their responses towards prevention knowledge and preventive behavior related questions (P<0.05. Thus, it is suggested that health education on toxoplasmosis and primary behavioral practices should be consistently offered to reproductive age women in general and pregnant women in particular. This information could help to reduce vertical transmission of Toxoplasma infection during pregnancy.
Jaros, F; Kascák, M
The authors treated successfully a patient who ingested along with three members of the family the mushroom Amanita phalloides and was in the 24th week of gestation. She gave birth to a healthy infant. The authors discuss the incidence and contemporary treatment of cytotoxic, cyclopeptide (phalloid, hepatotoxic) intoxications, incl. those with Amanita phalloides during pregnancy. They present case-histories and an account on amatoxin intoxications in pregnant women published so far in the literature, and experience with the treatment of a 18-year-old pregnant woman. They reflect whether termination of pregnancy is indicated in pregnant women intoxicated with Amanita phalloides. PMID:8928413
In the work, systemic and structural analysis of causes and dynamics of the morbidity of pregnant women and newborns in the Gomel, Mogilov and Brest area during the period from 1986 to 2001 has been made. The pregnant morbidity rate of anemias, urogenital system diseases, late gestosis, as well as of newborn morbidity rate of acute viral infections, intrauterus hypoxia and asphyxia, respiratory distress-syndrome, birth traumas and inborn pneumonias was higher on the radionuclide contaminated territories. The main directions for improvement of medical care to pregnant women and the ways of their realization have been determined (authors)
Bischoff, Anne Louise; Følsgaard, Nilofar Vahman; Carson, Charlotte Giwercman; Stokholm, Jakob; Pedersen, Louise; Holmberg, Maria; Bisgaard, Amalie; Birch, Sune; Tsai, Theodore F; Bisgaard, Hans
BACKGROUND: Pregnant women were suspected to be at particular risk when H1N1pnd09 influenza became pandemic in 2009. Our primary objective was to compare the immune responses conferred by MF59®-adjuvanted vaccine (Focetria®) in H1N1pnd09-naïve pregnant and non-pregnant women. The secondary aims were to compare influences of dose and adjuvant on the immune response. METHODS: The study was nested in the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC2010) pregnancy cohort in 2009-201...
Vírginia da Conceição Ribes Amorim Bezerra, Brandão; Heloisa Ramos, Lacerda; Norma, Lucena-Silva; Ricardo Arraes de Alencar, Ximenes.
Full Text Available Women with human immunodeficiency virus (HIV) infection present a higher risk of infection by the human papillomavirus (HPV) and cervical cancer. To determine HPV genotypes and frequencies among HIV-positive women, an analytical cross-sectional study was carried out on 147 women (51 were pregnant an [...] d HIV-positive, 45 pregnant and HIV-negative and 51 HIV-positive and not pregnant), who were attended at a maternity hospital in Recife between April 2006-May 2007. They answered a questionnaire and underwent a gynaecological examination, with samples collected for HPV investigation by PCR, hybrid capture II, oncotic colpocytology (Papanicolau) and colposcopy. The frequency of HPV DNA was 85.3% (122/143), with a high proportion of HPV types that have been identified as high risk for cervical cancer. Among HIV-positive pregnant women, there was an HPV prevalence of 96% (48/50), of whom 60.4% (29/48) were high-risk. HPV 16, 58, 18, 66 and 31 were the most frequent types. Colpocytological abnormalities were observed in 35.3% (18/51) of HIV-positive non-pregnant women, 21.6% (11/51) of HIV-positive pregnant women and 13.3% (6/45) of HIV-negative pregnant women with a predominance of low-level lesions. A high prevalence of HPV infection was identified, especially with the high-risk types 16, 58, 18 and 66. This study identified high-risk HPV types in all three groups examined (HIV-positive pregnant women, HIV-negative pregnant women and HIV-positive not pregnant), characterising its distribution in this setting.
Nabhi VR. Murty
Full Text Available Background: Thyroid dysfunction is one of the commonest endocrinopathies seen in pregnancy and affects both maternal and fetal outcomes. There is little data available on its prevalence in Indian pregnant women. This study was conducted at Bhaskar medical college and hospital situated in a rural/suburban area near Hyderabad, Telengana, India. The aim of the study was to find out the prevalence of thyroid disease among pregnant women. Methods: All consecutive pregnant women registered from January 2014 to December 2014 were included in the study. Morning samples of serum were tested for T3, T4 and TSH. Results: A total of 1340 women were included in the study. 260 pregnant women (19.41% had TSH values more than 3.0 mIU/L, the cut-off value used for upper limit of normal in this study. Out of these, 216 had normal T4 value, hence labeled as subclinical hypothyroidism and 44 had low T4, hence termed overt hypothyroidism. Three pregnant women had overt hyperthyroidism and 11 had subclinical hyperthyroidism. Nine women had low T4 values-Isolated hypothyroidism. Conclusions: Prevalence of thyroid disease in pregnancy was found to be higher in our patients, more so the sub clinical hypothyroidism. [Int J Reprod Contracept Obstet Gynecol 2015; 4(2.000: 453-456
Copersino, Marc L.; Jones, Hendrée; Tuten, Michelle; Svikis, Dace
The current retrospective study compared the psychiatric and lifestyle characteristics of two groups of treatment-seeking pregnant, opiate and/or cocaine dependent women admitted to the Center for Addiction and Pregnancy (CAP). Women reporting past and/or current suicidal ideation (SI) (46%; n = 35) were compared to women who did not report thoughts of suicidal ideation (NSI) (54%; n = 41). SI women were more likely to be homeless (p = .020), to report histories of emotional (p = .022), physi...
Zhang, Haihong; Lv, Shengmin; Mu, Zhenguo; Li, Weihong; Zhang, Xia; Wang, Yuchun; Rutherford, Shannon
Sufficient iodine intake by pregnant and lactating women is crucial to their offspring's cognitive development. The aim of the present study was to explore the impact of iodised salt intake on the iodine status of pregnant and lactating women. Thirty towns were selected from 211 towns in the rural areas of Shijiazhuang city using probability proportionate to size sampling in this cross-sectional survey. In each selected town, forty pregnant women and forty lactating women were randomly selected to contribute urine samples to determine iodine content. The median urinary iodine content (UIC) of 1200 pregnant women in all was 146 (interquartile range (IQR) 88-239) ?g/l. The median UIC in the first, second and third trimesters were 166 (IQR 92-276) ?g/l, 145 (IQR 83-248) ?g/l and 134 (IQR 79-221) ?g/l, respectively. The median UIC in the first trimester was significantly higher than that in the third trimester (P= 0.04). The median UIC of 1200 lactating women in all was 120 (IQR 66-195) ?g/l. Their median UIC in every 4-week block was higher than the WHO criteria except in weeks 25-28 and weeks 33-36 of lactation. Pregnant women's median UIC did not correlate with median salt iodine (MSI) (P= 0.402); however, there was a linear correlation between MSI and the lactating women's median UIC (P= 0.007). Iodised salt failed to provide adequate iodine to pregnant women possibly due to limited intake of iodised salt during pregnancy, though it was found to provide adequate iodine to lactating women in the rural areas of Shijiazhuang city. PMID:26058867
Akinbami, Akinsegun A; Ajibola, Sarah O; Rabiu, Kabiru A; Adewunmi, Adeniyi A; Dosunmu, Adedoyin O; Adediran, Adewumi; Osunkalu, Vincent O; Osikomaiya, Bodunrin I; Ismail, Kamal A
Background Hematological profile is considered one of the factors affecting pregnancy and its outcome. Anemia is the most common hematological problem in pregnancy, followed by thrombocytopenia. Leukocytosis is almost always associated with pregnancy. The study reported here was designed to evaluate the overall mean values of seven major hematological parameters and their mean values at different trimesters of pregnancy. Subjects and methods This examination was a cross-sectional study of 274 pregnant women who registered to attend the Lagos University Teaching Hospital or Lagos State University Teaching Hospital antenatal clinics between their first and third trimester. Blood (4.5 mL) was collected from each participant into a tube containing the anticoagulant ethylenediaminetetraacetic acid (EDTA). A full blood count was performed on each sample and the results were analyzed. Results Overall, the values obtained were (mean ± standard deviation [SD]): hematocrit level, 30.16% ± 5.55%; hemoglobin concentration, 10.94 ± 1.86 g/dL; white blood cells, 7.81 ± 2.34 × 109; platelets, 228.29 ± 65.6 × 109; cell volume 78.30 ± 5.70 fL, corpuscular hemoglobin, 28.57 ± 2.48 pg; and corpuscular hemoglobin concentration, 36.45 ± 1.10 g/dL. When grouped by trimester, the mean ± SD value of packed cell volume at first trimester was 32.07% ± 6.80%; of second trimester, 29.76% ± 5.21%; and of third, 33.04% ± 3.88%. The mean ± SD hemoglobin concentration values were 11.59 ± 2.35 g/dL, 10.81 ± 1.72 g/dL, and 10.38 ± 1.27 g/dL for women in their first, second, and third trimester, respectively. Mean ± SD white blood cell concentration for first, second, and third trimesters were 7.31 ± 2.38 × 109, 7.88 ± 2.33 × 109, and 8.37 ± 2.15 × 109, respectively, while the mean ± SD platelet values for first, second, and third trimesters were 231.50 ± 79.10 × 109, 227.57 ± 63 × 109, and 200.82 ± 94.42 × 109, respectively. A statistically significant relationship was found to exist between packed cell volume and white blood cell count with increase in gestational age (P = 0.010 and 0.001, respectively). However, there was no statistically significant association between platelet count and increase in gestational age (P = 0.296). Conclusion These findings reinforce the need for supplementation and provide additional information on hematological reference values in pregnancy in Nigeria. PMID:23662089
Full Text Available Abstract Background Substance abuse during pregnancy may harm the foetus and can cause neonatal abstinence syndrome. Exposure to alcohol and other substances can influence the child for the rest of its life. A special child welfare clinic was set up in 1994 in Kristiansand, Norway, targeting pregnant women with substance abuse problems in the county of Vest-Agder. Pregnancy is not an indication for opioid replacement therapy in Norway, and one of the clinic's aims was to support the drug dependent women through their pregnancy without any replacements. The object of this paper is to describe concurrent health and social problems, as well as the predictors for stopping drug abuse, in the clinic's user group. Methods Retrospective cohort study. Data was gathered from the medical records of all 102 women seen in the clinic in the period between 1992 and 2002. The study includes 59 out of 60 women that were followed until their children were two years old or placed in alternative care, and a comparison group of twice the size. Both groups were presented with a questionnaire concerning both the pregnancy and health and socio-economic issues. Results Four (4.5 percent of the women that completed their pregnancies did not manage to reduce their substance abuse. All the others reduced their substance abuse considerably. The odds ratio for stopping substance abuse within the first trimester was significantly associated with stopping smoking (O.R. 9.7 or being victims of rape (O.R. 5.3. Conclusion A low cost and low threshold initiative organised as a child welfare clinic may support women with substance abuse problems in their efforts to stop or reduce their substance abuse during pregnancy.
Roth Daniel E
Full Text Available Abstract Background Improvements in antenatal vitamin D status may have maternal-infant health benefits. To inform the design of prenatal vitamin D3 trials, we conducted a pharmacokinetic study of single-dose vitamin D3 supplementation in women of reproductive age. Methods A single oral vitamin D3 dose (70,000 IU was administered to 34 non-pregnant and 27 pregnant women (27 to 30 weeks gestation enrolled in Dhaka, Bangladesh (23°N. The primary pharmacokinetic outcome measure was the change in serum 25-hydroxyvitamin D concentration over time, estimated using model-independent pharmacokinetic parameters. Results Baseline mean serum 25-hydroxyvitamin D concentration was 54 nmol/L (95% CI 47, 62 in non-pregnant participants and 39 nmol/L (95% CI 34, 45 in pregnant women. Mean peak rise in serum 25-hydroxyvitamin D concentration above baseline was similar in non-pregnant and pregnant women (28 nmol/L and 32 nmol/L, respectively. However, the rate of rise was slightly slower in pregnant women (i.e., lower 25-hydroxyvitamin D on day 2 and higher 25-hydroxyvitamin D on day 21 versus non-pregnant participants. Overall, average 25-hydroxyvitamin D concentration was 19 nmol/L above baseline during the first month. Supplementation did not induce hypercalcemia, and there were no supplement-related adverse events. Conclusions The response to a single 70,000 IU dose of vitamin D3 was similar in pregnant and non-pregnant women in Dhaka and consistent with previous studies in non-pregnant adults. These preliminary data support the further investigation of antenatal vitamin D3 regimens involving doses of ?70,000 IU in regions where maternal-infant vitamin D deficiency is common. Trial registration ClinicalTrials.gov (NCT00938600
Arikan, Tugba Atilan
The thyroid gland has the highest selenium (Se) concentration per unit weight among all tissues. The aims of the present study were to evaluate the Se levels in the plasma of hyperthyroidic pregnant women and to investigate the association between maternal plasma Se concentrations and thyroid hormone levels. The study population consisted of 107 pregnant women, 70 healthy pregnant women (group 1) and 37 pregnant women with hyperthyroidism (group 2). The plasma free triiodothyronine (fT3) and free thyroxine (fT4) levels were significantly higher, and the plasma thyroid-stimulating hormone (TSH) and Se levels were significantly lower in group 2 than in group 1 (p?hyperthyroidic pregnant women compared with normal pregnant women supported the hypothesis that hyperthyroidism was associated with decreased antioxidant response. PMID:25796516
Hampson, Elizabeth; Phillips, Shauna-Dae; Duff-Canning, Sarah J; Evans, Kelly L; Merrill, Mia; Pinsonneault, Julia K; Sadée, Wolfgang; Soares, Claudio N; Steiner, Meir
This article is part of a Special Issue "Estradiol and cognition". Subjective changes in concentration and memory are commonly reported by women during the second or third trimesters of pregnancy, but the nature of the problem is poorly understood. We hypothesized that these self-reports might reflect difficulties in working memory (WM). It was further hypothesized that antepartum depression (depression arising during pregnancy) may play an etiological role, either on its own or due to secondary changes in endocrine function or sleep. Using WM tasks that emphasized executive control processes mediated by the prefrontal cortex (PFC) we compared pregnant women tested at 34-36 weeks of gestation (n = 28) with age- and education-matched non-pregnant controls (n = 26). All pregnant women were screened for depression. Evidence of a WM disturbance was found, and was evident only among pregnant women showing depressive symptoms. In contrast, pregnant women who were not depressed showed WM performance that equalled, or even significantly exceeded, non-pregnant controls. No significant differences were observed on control tests of other cognitive functions. Multiple regression revealed that serum estradiol concentrations, along with severity of depressive affect but not sleep disruption, significantly predicted variation in the WM scores. In agreement with studies of estradiol and WM in other contexts, higher estradiol was associated with better WM, while higher levels of depressive symptoms predicted poorer WM. We conclude that memory disturbance during gestation might not be as widespread as commonly believed, but can be seen among women experiencing antepartum depression. The high level of WM performance found in healthy, non-depressed, pregnant women is discussed from an adaptationist perspective. PMID:26187710
Background: Pregnant women constitute a high risk group for iron deficiency. Maternal iron deficiency and particularly iron deficiency anaemia may be associated with detrimental effects on maternal and infant function and particularly with a higher risk of preterm delivery and delivery of low birth weight neonates. Objective of this study was to assess and compare the iron status of normal healthy non-pregnant women with that of pregnant women of Hazara Division. Methods: This study was conducted at Faculty of Health Sciences, Hazara University, and Ayub Medical College, Abbottabad from first March to /31 August 2006. Altogether 120 women, 90 pregnant at various stages of pregnancy and 30 non-pregnant women as control group were included in this study by convenience sampling. Their iron status was assessed by determination of haemoglobin (Hb), Serum ferritin, Serum-iron, Total Iron Binding Capacity (TIBC), Unsaturated Iron Binding Capacity (UIBC), and Percentage saturation of transferrin. Data generated on these variables were subjected to ANOVA and correlation analysis. Results: The salient finding of this study is a significant decrease in Hb, Serum ferritin, Serum iron, percentage saturation of transferrin and a significant increase in values of TIBC and a pronounced increase in UIBC in second and third trimester compared to first trimester in iron deficient pregnant women. The mean values of Hb, SF, and Fe/TIBC% were significantly lower in the cases than in the control and significantly higher values of TIBC and UIBC were observed in the cases compared to controls. Significant correlations were observed for TIBC, UIBC and Fe/TIBC% against serum iron in different trimesters of pregnancy. Conclusion: A high percentage of the pregnant women are iron deficient due to factors such as high parity, poor dietary habits and socioeconomic status. (author)
Full Text Available Objective(sRapid tests for detection of Streptococcus agalactiae or Group B Streptococci (GBS at the onset of labor are needed to permit early intrapartum antibiotic prophylaxis. This study aimed to evaluate the PCR assays targeting the 16S ribosomal RNA gene (16S rDNA for detection of the GBS in comparison with a specific culture method. Materials and MethodsTwo swabs were used to obtain vaginal specimens from the 330 pregnant women attended delivery room at Hedayat hospital, Tehran, Iran. One swab was analyzed by direct plating onto selective GBS agar medium (ISLAM and the other swab was used for a PCR assay, which amplified the 16S rDNA of S. agalactiae. Comparative study between the selective culture and the PCR assay was done among the 330 tested women.ResultsThe GBS colonization rate based on the culture results was 20.6% (68/330. Both culture and PCR methods were positive for 56 and negative for 253 women. The culture method was positive and PCR was negative in 12 women. The culture was negative and the PCR positive for 9 women. Sensitivity of the PCR assay was 82.3% and specificity was 96.5%. The positive predictive value was 86.15% and negative predictive value was 95.4%. ConclusionISLAM diagnostic procedure and PCR are rapid and reliable analyzing methods, which might be useful for accurate diagnosis of GBS colonization in pregnant women at the time of delivery.
FMR, Lopes; R, Mitsuka-Breganó; DD, Gonçalves; RL, Freire; CJT, Karigyo; GF, Wedy; T, Matsuo; EMV, Reiche; HK, Morimoto; JD, Capobiango; IT, Inoue; JL, Garcia; IT, Navarro.
Full Text Available The aim of this study was to evaluate associations between seropositivity for IgG and IgM anti-Toxoplasma gondii antibodies and socio-economic and environmental variables in pregnant women of Londrina, state of Paraná, Brazil. We interviewed 492 pregnant women, each of whom answered an epidemiologic [...] al questionnaire, and collected blood samples for measurement of IgG and IgM anti-T. gondii antibodies by chemiluminescence. A confirmatory diagnosis of acute infection was made by an IgG avidity test. Titres of specific IgG anti-T. gondii were obtained by IFAT. Seropositivity for IgG anti-T. gondii antibodies was observed in 242 women (49.2%) and, of these, six pregnant women (1.2%) showed seropositivity for IgM. Age group, level of education, per capita income, presence of a cat in the house and a habit of eating green vegetables were all factors associated with a greater chance of infection with T. gondii. This study showed that 250 (50.8%) pregnant women were susceptible to T. gondii and considered to be at high risk for toxoplasmosis during pregnancy. Based on the results obtained, is critical to establish a program of health surveillance for toxoplasmosis, in order to contribute to diagnosis and early treatment during the prenatal period. It is also necessary to introduce measures to prevent the Toxoplasma infection in seronegative pregnant women.
Full Text Available The aim of this study was to evaluate associations between seropositivity for IgG and IgM anti-Toxoplasma gondii antibodies and socio-economic and environmental variables in pregnant women of Londrina, state of Paraná, Brazil. We interviewed 492 pregnant women, each of whom answered an epidemiological questionnaire, and collected blood samples for measurement of IgG and IgM anti-T. gondii antibodies by chemiluminescence. A confirmatory diagnosis of acute infection was made by an IgG avidity test. Titres of specific IgG anti-T. gondii were obtained by IFAT. Seropositivity for IgG anti-T. gondii antibodies was observed in 242 women (49.2% and, of these, six pregnant women (1.2% showed seropositivity for IgM. Age group, level of education, per capita income, presence of a cat in the house and a habit of eating green vegetables were all factors associated with a greater chance of infection with T. gondii. This study showed that 250 (50.8% pregnant women were susceptible to T. gondii and considered to be at high risk for toxoplasmosis during pregnancy. Based on the results obtained, is critical to establish a program of health surveillance for toxoplasmosis, in order to contribute to diagnosis and early treatment during the prenatal period. It is also necessary to introduce measures to prevent the Toxoplasma infection in seronegative pregnant women.
Full Text Available
Research Goal was to compare probability of risk progression of chronic fetoplacental insuffciency with various disturbances of vegetative nervous system (VNS in pregnant women. Materials. Basic group consisted of 112 pregnant women with chronic fetoplacental insuffciency; control group included 73 women with physiological course of pregnancy and delivery. Status of VNS was determined with the purpose to estimate initial vegetative tone in various functional systems and forming concept of general vegetative status in the sample. Results. Presence of fetoplacental insuffciency in pregnant women was extensively associated with increase of sympathetic section tone and VNS lability. Occurrence frequency of critical indices of hemodynamics disturbances in the system mother- placenta-fetus revealed reliable correlation dependence on VNS lability and index of vegetative supply of activity. Conclusion. Pregnant women with fetoplacental insuffciency had 25?–?30?% increased tone and lability indices of VNS sympathetic section in contrast to physiological course of pregnancy. Progression of fetoplacental insuffciency was more often revealed in pregnant women in case of replacement of sympathicotonia by vagotonia, and against a background of high VNS lability and reactivity.
Full Text Available The investigation is dedicated to the study of the pathological alterations of cervical epithelium of uterus, proliferative activity in the lesion focuses and the improvement of cytological diagnosis of the state of cervical epithelium of uterus. The correlation between the proliferative processes in abnormal epithelium of uterine cervix and some pathological factors of the pregnant women organism was studied. The criteria for prognosis of the cervical epithelial dysplasia in pregnant women were elaborated on this basis of our data. The pathological processes in cervical epithelium were revealed in 309 pregnant women in the first trimester (mean age of women was 26,17±0,83 years. The hormonal state of pregnant women was studied on the basis of colpocytological picture and the colpocytological types which indicate the unfavorable prognosis with a certain degree of validity were determined. The mathematic model for all cytological groups of pregnant women for prognosis of inflammatory processes, epithelial dysplasia and preinvasive cervical cancer was created. The simple and comprehensible prognostic scheme for diagnosis of epithelial dysplasia and preinvasive cervical cancer was developed.
Jackson, Afton; Shannon, Lisa
Research presenting outcomes for women who enter substance abuse treatment during pregnancy consistently shows benefits. While treatment has nearly universal benefits, there are many barriers to seeking substance abuse treatment for pregnant women. The purpose of this study is to explore barriers for rural pregnant women seeking substance abuse treatment. There were three eligibility criteria for study participation: (1) aged 18 and older, (2) pregnant, and (3) undergoing short-term inpatient detoxification at the University of Kentucky Chandler Medical Center. Eighty-five rural women (N = 85) were included in the analysis. Substance use history and previous treatment were assessed with measures adapted from the Addiction Severity Index. Treatment barriers were measured with three qualitative questions and were coded into four overarching categories: availability, accessibility, affordability, and acceptability barriers. This sample had an extensive substance use history. Almost all participants had used alcohol (98%), marijuana (98%), illicit opiates (99%), and cigarettes (97%). On average, participants reported about two barriers to receiving treatment (Mean = 1.8; SD = 1.3), with over 80% of the sample reporting having experienced any barrier to treatment. The majority experienced acceptability (51%) and accessibility (49%) barriers. Twenty-six percent (26%) of the sample reported availability barriers. A smaller percentage of participants reported affordability barriers (13%). Rural pregnant women seeking substance abuse treatment face many obstacles to receiving needed treatment. More studies on barriers to substance abuse treatment among rural pregnant women are needed. Identifying these barriers can help in improving treatment access and services. PMID:22139045
Puente, Cecilia Penacoba; Monge, Francisco Javier Carmona; Abellan, Isabel Carretero; Morales, Dolores Marin
The authors examined the effects of personality and pregnancy worries on pregnant women's mental and physical health with 154 women in the first half of their gestational period. Self-report questionnaires were used to collect information about control variables, sociodemographic (age, educational level, and work), and pregnancy variables…
Full Text Available Abstract Background Striae gravidarum is a physiological skin change that many pregnant women experience during pregnancy. The striae are often accompanied by a reddish purple color during pregnancy, and then lose pigmentation and become atrophic in the long term after pregnancy. Striae gravidarum seems to be undesirable to many pregnant women. However, the impact of striae gravidarum on pregnant women who experience it has not been clarified. The aim of this study was to evaluate the impact of striae gravidarum on the generic and dermatology-specific quality of life (QOL of pregnant women. Methods A cross-sectional study was conducted at three private clinics in a typical urban area in Japan. We recruited 447 pregnant women at 36 weeks of gestation; One hundred and ninety-nine pregnant women at 36 weeks of gestation participated in the study and 179, consisting of 94 primiparae and 85 multiparae, were analyzed. We used and assessed Davey’s score for striae gravidarum, World Health Organization Quality of Life assessment questionnaire for generic QOL, and Skindex-29 for dermatology-specific QOL. Results The prevalence of striae gravidarum was 39.1% (27.7% in primiparae, and 51.8% in multiparae. Although there were no differences in generic QOL scores between the presence and absence of striae gravidarum and with their severity, the whole group of pregnant women and the multiparae group showed significant differences in scores on emotion of Skindex-29 between the presence and absence of striae gravidarum (p?=?0.012 and p?=?0.011. Pregnant women with severe striae gravidarum showed significantly higher scores on emotion of Skindex-29 compared with those with absent or mild striae gravidarum (p?p?=?0.005. Conclusions There was no difference in generic QOL of pregnant women between the presence and absence of striae gravidarum, although the occurrence and severity of striae gravidarum influenced their dermatology-specific QOL. Multiparae women were especially impaired by striae gravidarum and it is considered important to prevent or reduce the severity of striae gravidarum of the multiparae group.
As observed by Dr. Linda Dodds (see pages 185 to 190 of this issue), there has been little change in recent years in the smoking rate of about 30% among pregnant women in Nova Scotia. Women who smoke during pregnancy tend to be young, unmarried, undereducated and multiparous and tend not to go to prenatal classes. Many pregnant women find it extremely difficult to stop smoking even when they understand the risks to the fetus. Routine advice given by physicians on smoking cessation is clearly ...
Mwambe, Berno; Mirambo, Mariam M; Mshana, Stephen E.; Massinde, Anthony N; Kidenya, Benson R.; Michael, Denna; Morona, Domenica; Majinge, Charles; Groß, Uwe
Background Sero-positivity rates of the rubella virus among pregnant women vary widely throughout the world. In Tanzania, rubella vaccination is not included in the national immunization schedule and there is therefore no antenatal screening for this viral disease. So far, there are no reports on the sero-prevalence of rubella among pregnant women in Tanzania. As a result, this study was undertaken to establish the sero-positivity rate of rubella and rubella risk factors among pregnant women ...
Ali, Niloufer S; Azam, Iqbal S; Ali, Badar S; Tabbusum, Ghurnata; Moin, Sana S.
Antepartum anxiety and/or depression is a major public health problem globally. The aim of this study was to estimate the frequency of antepartum anxiety and/or depression among pregnant women. This was a cross-sectional study conducted in a tertiary care hospital among pregnant women. A total of 165 pregnant women were interviewed by a clinical psychologist using HADS for assessing anxiety and/or depression and also collected information regarding sociodemographic, obstetric, family relation...
Full Text Available To study the pregnancy outcomes in first trimester vaginal bleeding.This cross sectional study was done on 60 pregnant women with first trimester vaginal bleeding referring to university hospitals affiliated to Islamic Azad University, Tehran, Iran. All women were evaluated for the outcomes including abortion, preterm rapture of membranes, preterm labor, second and third trimester vaginal bleeding, low birth weight and intra uterine growth retardation and the mode of delivery. Data were analyzed using SPSS- 11.Placenta accreta, second trimester bleeding and preterm labor were significantly more prevalent in pregnant women with first trimester bleeding (P ? 0.05.According to results of present study vaginal bleeding in first trimester of pregnancy may predict further maternal and fetal complications. We recommend training pregnant women regarding those complications and their prevention.
Anderson Amy E
Full Text Available Abstract Background In 2009, Australian alcohol guidelines for pregnancy changed from low to no alcohol intake. Previous research found a high proportion of pregnant Australian women drank during pregnancy; however, there has been limited investigation of whether pregnant women comply with 2009 alcohol guidelines. The purpose of this study was to provide an assessment of pregnant women’s compliance with 2009 Australian alcohol guidelines and identify predictors of such compliance, including previous drinking behaviour. Methods Cross-sectional analysis of prospective data from the 1973–1978 cohort of the Australian Longitudinal Study on Women’s Health was conducted. Women aged 30–36?years who were pregnant at the 2009 survey and had data on alcohol use were included (n?=?837. Compliance with 2009 alcohol guidelines for pregnancy was defined as no alcohol intake. Predictors of compliance were analysed using multivariate logistic regression, controlling for area of residence, in three separate models to account for multicollinearity between measures of previous alcohol intake (compliance with 2001 guidelines; frequency and quantity; bingeing. Private health insurance, household income, and illicit drug use were entered into all models and retained if significant. Results 72% of pregnant women did not comply with the 2009 alcohol guidelines and 82% of these women drank less than seven drinks per week, with no more than one or two drinks per drinking day. The odds of complying with abstinence increased by a factor of 3.48 (95% CI 2.39-5.05 for women who previously complied with the 2001 alcohol guidelines and decreased by a factor of 0.19 (95% CI 0.08-0.66 if household incomes were $36,400 or more. In other models the odds of complying were lower for women who consumed alcohol before pregnancy at least weekly (OR?=?0.40, 95% CI 0.25-0.63 or binged (OR???0.18, 95% CI 0.10-0.31 and were higher for those who abstained (OR?=?45.09; 95% CI 8.63-235.49 prior to pregnancy. Conclusion Most pregnant women did not comply with alcohol guidelines promoting abstinence. Prior alcohol behaviour was the strongest predictor of compliance during pregnancy, suggesting alcohol use should be addressed in women of child-bearing age. The study is limited by the relatively short timeframe between the official introduction of the 2009 guidelines and the date the surveys were sent out. Widespread dissemination of the guidelines may be necessary to help increase guideline compliance by pregnant women.
Juhl, Mette; Madsen, Mia
Physical activity is recommended during pregnancy, although strong evidence on reproductive health is lacking. We present exercise habits and predictors of exercise during pregnancy. From the Danish National Birth Cohort (1996-2002), 88 200 singleton pregnancies were analyzed in logistic regression. About one-third of the women exercised in early/mid pregnancy and slightly less in late pregnancy. Bicycling, swimming, and low-impact activities were most common. Exercising more than three times per week was strongly correlated with older age, being a student or out of work, eating disorders, moderate alcohol consumption, and a healthy diet. Multiparity, a normal or less good self-rated health, smoking, and a less health conscious diet were the strongest predictors of not doing exercise. Women of 25 years or older, with metabolic or psychiatric disorders, or who had received subfecundity treatment were more likely to increase their activity level substantially from early to late pregnancy than comparison groups.In conclusion, exercising during pregnancy correlated with a number of maternal characteristics. The findings may be used to identify pregnant women not likely to exercise, to target activities that may fit their needs, and, for research purposes, to identify adjustment variables or guide sensitivity analyses when data on confounders are lacking.
Juhl, M; Madsen, M; Andersen, A-M N; Andersen, P K; Olsen, J
Physical activity is recommended during pregnancy, although strong evidence on reproductive health is lacking. We present exercise habits and predictors of exercise during pregnancy. From the Danish National Birth Cohort (1996-2002), 88,200 singleton pregnancies were analyzed in logistic regression. About one-third of the women exercised in early/mid pregnancy and slightly less in late pregnancy. Bicycling, swimming, and low-impact activities were most common. Exercising more than three times per week was strongly correlated with older age, being a student or out of work, eating disorders, moderate alcohol consumption, and a healthy diet. Multiparity, a normal or less good self-rated health, smoking, and a less health conscious diet were the strongest predictors of not doing exercise. Women of 25 years or older, with metabolic or psychiatric disorders, or who had received subfecundity treatment were more likely to increase their activity level substantially from early to late pregnancy than comparison groups. In conclusion, exercising during pregnancy correlated with a number of maternal characteristics. The findings may be used to identify pregnant women not likely to exercise, to target activities that may fit their needs, and, for research purposes, to identify adjustment variables or guide sensitivity analyses when data on confounders are lacking. PMID:20500556
Full Text Available Background: About one-third of the global population is anaemic. WHO has estimated that prevalence of anaemia in pregnant women is 18% in developed countries and relatively high 56% in developing countries. Prevalence of anaemia in South East Asian countries is highest in the world. WHO estimates that even among the South East Asian countries, India has the highest prevalence of anaemia. Aims & Objectives: To determine the prevalence of anaemia among pregnant women and to determine association of anaemia with its socio-demographic factors. Material & Methods: A descriptive cross sectional study was conducted among pregnant women 2nd trimester onwards who came to ante natal clinic of obstetrics and gynaecology department during January-March 2014 by using pre-designed, pretested schedule. A total of 300 pregnant women were clinically examined. Written consent was taken. Haemoglobin estimation was done by Cyanmethaemoglobin method and anaemia was graded according to WHO criteria. Statistical analysis was done using Microsoft Excel 2007 and SPSS Version 17. Results: Overall prevalence of anaemia among the pregnant women was found to be 58.3%. It was seen that 31% of women were illiterate and 38.7% of them belong to upper middle class. Factors such as level of education of women, occupation and consumption of Iron Folic Acid were found to be significantly associated with prevalence of anaemia in pregnancy. Conclusion: A very high prevalence of anaemia in pregnancy needs awareness about late marriage, birth spacing, one or two child norm, antenatal care, green leafy vegetable in diet, mandatory regular supply of IFA tablets to adolescent and pregnant women along with correction of other nutritional deficiencies.
Sui Z; Dodd JM
Zhixian Sui,1 Jodie M Dodd1,21The University of Adelaide, Robinson Institute, Discipline of Obstetrics and Gynaecology, Women’s and Children’s Hospital, 2Department of Perinatal Medicine, Women’s and Babies Division, Women’s and Children’s Hospital, Adelaide, SA, AustraliaAbstract: Overweight and obesity have significant implications during pregnancy and childbirth. The objective of this review was to provide a comprehensive overview of the effect of physical act...
Say Rebecca; Thomson Richard; Robson Stephen; Exley Catherine
Abstract Background Women who have a breech presentation at term have to decide whether to attempt external cephalic version (ECV) and how they want to give birth if the baby remains breech, either by planned caesarean section (CS) or vaginal breech birth. The aim of this study was to explore the attitudes of women with a breech presentation and health professionals who manage breech presentation to ECV. Methods We carried out semi-structured interviews with pregnant women with a breech prese...
To determine the prevalence of Hypovitaminosis D in pregnant women and in cord blood of their newborns. Serum calcium, phosphorus and 25(OH) Vit D, were measured in 193 pregnant subjects between 16-45 years of age in third trimester admitted in Be'sat hospital. Same were measured in the cord blood of 193 newborns belonging to them. Mean maternal serum 25(OH) Vit D was 16.5+-14.2 ng/mL, and cord blood was 12+-0.2 ng/mL. Fifty-seven percent of pregnant women had 25(OH) Vit D values below the cutoff level. Seventy six percent of newborns had 25(OH) Vit D values below the cutoff level. Maternal serum 25(OH) Vit D correlated positively with cord 25(OH) Vit D (r=0.77, P<0.05). Mean maternal serum calcium was 8.89+-0.73 mg/ml and mean newborn serum calcium was 9.46+-0.93. Mean maternal serum calcium correlated with mean newborn serum calcium (r= 0.38, P<0.05). Twenty six percent of women and 37.8% of newborns had hypocalcemia. There was a high prevalence of significant hypovitaminosis D among pregnant women and their newborns. Our study emphasize the need of majority of pregnant women and their newborns to supplemental vitamin D and has significant public health implications. (author)
Figueiredo, Bárbara; Bifulco, A.; Pacheco, Alexandra P.; Costa, Raquel A.; Magarinho, Rute
The aim of this portuguese study is to compare the experience of pregnancy in teenage years and later adulthood and to examine insecure attachment style as a risk factor for depression during pregnancy. The Attachment Style Interview (ASI; Bifulco, Moran, Ball & Bernazzani, 2002) and the Edinburgh Postnatal Depression Scale (EPDS; Cox, Holden, & Sagovsky, 1987) were administered to 66 pregnant adolescents and 64 adult women. Pregnant teenagers were found to be nearly three times more likely t...
Godin, G; Vezina, L; Leclerc, O
The aim of this study was to identify factors that may influence a pregnant woman's decision to exercise after giving birth. A sample of 98 pregnant women were asked to complete a questionnaire investigation attitudes, social norms, perceived barriers to exercise, and intention regarding exercising after giving birth. Also determined were age, education level, exercise habits, number of months elapsed since onset of present pregnancy, and number of children. The regressions of intentions to e...
Giuseppina Messina; Elisa Colombo; Elena Cassinerio; Claudia Cesaretti; Alessia Marcon; Laura Zanaboni; Marina Baldini; Maria Domenica Cappellini
Background. The reproductive and sexual health issues concerning persons affected by thalassemia major are complex. The study was planned to investigate the psychological attitudes and expectations in a group of thalassemic pregnant women attending hospital for regular blood transfusion. Methods. The study included 20 consecutive thalassemic patients and a control group of 42 healthy pregnant volunteers. We evaluated the personality structure by Rorschach's test and the presence of psych...
Buffolano, W.; Gilbert, R.; Holland, F.; Fratta, D.; Palumbo, F.; ADES, A. E.
Effective primary prevention of congenital toxoplasmosis requires up to date information on locally relevant risk factors for infection in pregnant women. In Naples, risk factors for toxoplasma infection were compared in recently infected women (as assessed by detection of specific IgM in serum) and susceptible, IgG negative women. Recent infection was strongly associated with frequency of consumption of cured pork and raw meat. Eating cured pork or raw meat at least once a month increased th...
Buffolano, W.; Gilbert, R E; Holland, F. J.; Fratta, D.; Palumbo, F.; ADES, A. E.
Effective primary prevention of congenital toxoplasmosis requires up to date information on locally relevant risk factors for infection in pregnant women. In Naples, risk factors for toxoplasma infection were compared in recently infected women (as assessed by detection of specific IgM in serum) and susceptible, IgG negative women. Recent infection was strongly associated with frequency of consumption of cured pork and raw meat. Eating cured pork or raw meat at least once a month increased th...
Giurgescu, Carmen; KAVANAUGH, KAREN; Norr, Kathleen F.; Dancy, Barbara L.; Twigg, Naomi; McFarlin, Barbara L.; Engeland, Christopher G.; Hennessy, Mary Dawn; White-Traut, Rosemary C.
This research aimed to develop an initial understanding of the stressors, stress responses, and personal resources that impact African American women during pregnancy, potentially leading to preterm birth. Guided by the ecological model, a prospective, mixed-methods, complementarity design was used with 11 pregnant women and 8 of their significant others. Our integrated analysis of quantitative and qualitative data revealed 2 types of stress responses: high stress responses (7 women) and low ...
Rydbeck, Filip; Bottai, Matteo; Tofail, Fahmida; Persson, Lars-Åke; Kippler, Maria
Iodine is an essential dietary element required for normal fetal growth and development. We aimed to explore intraindividual and interindividual variations in iodine intake in pregnant women and whether non-dietary factors might influence the intake. Iodine intake was assessed in 271 women, residing in Matlab, rural Bangladesh, by measuring their urinary iodine concentration (UIC) at gestational week (GW) 8, 14, 19, and 30 with inductively coupled plasma mass spectrometry. The women's UIC inc...
Full Text Available Background and Aim: Group B streptococcus(GBS(Streptococcus agalactiae is the leading cause of morbidity and mortality of the newborn infant and accounted as a factor leading septicemia after birth in mothers. Infections in infants are usually acquired by contact with the genital tract of the mother during labor and delivery. So a rapid screening test for group B streptococcus that could accurately identify pregnant women who are carrying the bacteria at the time of delivery would obviate the need for prenatal screening.The goal of this study was molecular epidemiology of group B beta Hemolytic Streptococcal(GBS colonization in the vaginal flora of pregnant women. Materials and Methods: Samples were taken from mucus of anal and vaginal of 250 pregnant women during 35-37 weeks ingestion by swap. Samples were tested by standard culture using Todd Hewitt Broth and Blood Agar and also by PCR using cfb gene.Results: Culture identified 21(8.4% women as carriage of GBS from 250 women but PCR assay could identify 24(9/6% women. In comparison to culture results, sensitivity, NPV Specificity PPV of PCR Were(100%, 100% and 97%, 82% respectively. The times that used for PCR assay and culture were 2h and 36h respectively. Conclusion: In conclusion, we found that group B streptococci can be detected rapidly and reliably by a PCR assay of combined vaginal and anal secretions from pregnant women at the time of delivery. Also this study shows that incidence of GBS is at high rate in Iranian pregnant woman, so we recommend screening of pregnant woman for detecting of GBS emphatically.
Sabrina Maria Saueia, Ferreira; Anderson Marliere, Navarro; Patrícia Künzle Ribeiro, Magalhães; Léa Maria Zanini, Maciel.
Full Text Available Objetivo : O consumo de quantidade adequada de iodo durante a gestação é de fundamental importância para o desenvolvimento neurológico do feto. O objetivo deste estudo foi avaliar o estado nutricional iódico em gestantes do estado de São Paulo, Brasil.Material e métodos : Analisamos a concentração u [...] rinária de iodo (UIC) em 191 gestantes e em 58 mulheres não gestantes de mesma faixa etária. Foram utilizados os critérios da OMS para definir suficiência iódica (mediana de UIC: 150-249 µg/L entre as gestantes e 100-199 µg/L para as não gestantes).Resultados : A mediana de UIC das gestantes estudadas esteve abaixo da recomendada (mediana = 137,7 ?g/L; 95% IC = 132,9 – 155,9) enquanto a das mulheres não grávidas se mostrou na faixa adequada (mediana = 190 ?g/L; 95% IC = 159,3 – 200,1). Entre as gestantes, 57% apresentaram UIC Abstract in english Objective : The intake of adequate amounts of iodine during pregnancy is essential for the neurological development of the fetus. The aim of this study was to assess iodine nutrition status in pregnant women from the state of São Paulo, Brazil.Material and methods : We analyzed urinary iodine concen [...] tration (UIC) in 191 pregnant and 58 non-pregnant women matched by age. We used the World Health Organization criteria to define sufficient iodine supply (median UIC: 150-249 µg/L among pregnant women, and 100-199 µg/L for non-pregnant women).Results : Median UIC of the pregnant women studied was lower than the recommended value (median = 137.7 µg/L, 95% CI = 132.9 – 155.9), while non-pregnant women had UIC levels within the appropriate range (median = 190 ?g/L; 95% IC = 159.3-200.1). UIC was below 150 µg/L in 57% of the pregnant women.Conclusions : Although a larger sample is needed to consolidate these findings, these results raise concerns about the adequacy of the iodine supply of pregnant women in Brazil, especially considering the new determinations of the Brazilian government, which have recently reduced the concentrations of iodine in table salt to 15-45 mg/kg of salt. Arq Bras Endocrinol Metab. 2014;58(3):282-7
Full Text Available Akinsegun A Akinbami,1 Sarah O Ajibola,2 Kabiru A Rabiu,3 Adeniyi A Adewunmi,3 Adedoyin O Dosunmu,1 Adewumi Adediran,4 Vincent O Osunkalu,4 Bodunrin I Osikomaiya,5 Kamal A Ismail,51Department of Haematology and Blood Transfusion, Lagos State University, College of Medicine, 2Department of Haematology and Blood, Lagos University Teaching Hospital, 3Department of Obstetrics and Gynaecology, Lagos State University, College of Medicine, 4Department of Haematology and Blood, Faculty of Clinical Sciences, College of Medicine, University of Lagos, 5Department of Haematology and Blood Transfusion, Lagos State University Teaching Hospital, Lagos, NigeriaBackground: Hematological profile is considered one of the factors affecting pregnancy and its outcome. Anemia is the most common hematological problem in pregnancy, followed by thrombocytopenia. Leukocytosis is almost always associated with pregnancy. The study reported here was designed to evaluate the overall mean values of seven major hematological parameters and their mean values at different trimesters of pregnancy.Subjects and methods: This examination was a cross-sectional study of 274 pregnant women who registered to attend the Lagos University Teaching Hospital or Lagos State University Teaching Hospital antenatal clinics between their first and third trimester. Blood (4.5 mL was collected from each participant into a tube containing the anticoagulant ethylenediaminetetraacetic acid (EDTA. A full blood count was performed on each sample and the results were analyzed.Results: Overall, the values obtained were (mean ± standard deviation [SD]: hematocrit level, 30.16% ± 5.55%; hemoglobin concentration, 10.94 ± 1.86 g/dL; white blood cells, 7.81 ± 2.34 × 109; platelets, 228.29 ± 65.6 × 109; cell volume 78.30 ± 5.70 fL, corpuscular hemoglobin, 28.57 ± 2.48 pg; and corpuscular hemoglobin concentration, 36.45 ± 1.10 g/dL. When grouped by trimester, the mean ± SD value of packed cell volume at first trimester was 32.07% ± 6.80%; of second trimester, 29.76% ± 5.21%; and of third, 33.04% ± 3.88%. The mean ± SD hemoglobin concentration values were 11.59 ± 2.35 g/dL, 10.81 ± 1.72 g/dL, and 10.38 ± 1.27 g/dL for women in their first, second, and third trimester, respectively. Mean ± SD white blood cell concentration for first, second, and third trimesters were 7.31 ± 2.38 × 109, 7.88 ± 2.33 × 109, and 8.37 ± 2.15 × 109, respectively, while the mean ± SD platelet values for first, second, and third trimesters were 231.50 ± 79.10 × 109, 227.57 ± 63 × 109, and 200.82 ± 94.42 × 109, respectively. A statistically significant relationship was found to exist between packed cell volume and white blood cell count with increase in gestational age (P = 0.010 and 0.001, respectively. However, there was no statistically significant association between platelet count and increase in gestational age (P = 0.296.Conclusion: These findings reinforce the need for supplementation and provide additional information on hematological reference values in pregnancy in Nigeria.Keywords: anemia, thrombocytopenia, hematology, normal pregnancy, trimester
Full Text Available - To Compare colonization of group B streptococcus (GBS in diabetic and non-diabetic pregnant women. In this prospective study 50 pregnant women with diabetes mellitus (both pregestational and gestational and 43 pregnant women without diabetes between 33 and 37 weeks' gestation were evaluated. Three samples for Group B streptococcal culture detection were obtained from each subject in the following order: perinea sample, vaginal sample, and an anorectic sample. All had singleton gestations, negative tests for human immunodeficiency virus, and intact membranes at enrollment. Pearson chi-square and fisher, Exact test were used when appropriate. Most common site of GBS colonization in all women was vagina (11.8%. Colonization of group B streptococcus in control group included vagina (7% perineum (0.3% and rectum 0.3% and in diabetic group included vagina (16% perineum (16% and rectum (16%. Although comparison was shown higher vaginal colonization rate in diabetic group (16% versus 7% but difference was not significant (P=0.154.The prevalence of group B streptococcus colonization in gestational diabetes was 20% and higher than pregestational diabetic women. Among women with pregestational diabetes, the prevalence of group B streptococcus colonization was 15% in non-insulin dependent diabetic women and 10% in insulin dependent diabetic women (P> 0.05. Comparison between two groups showed high rectal colonization in diabetic group and difference was significant (P= 0.027. Pregnant diabetic patients have higher carriage rates of group B streptococcus (GBS in rectum than non-diabetic pregnant women and diabetes is a risk factor for group B streptococcus colonization during pregnancy.
Full Text Available Abstract Background Food frequency questionnaires (FFQs have been validated in pregnant women, but few studies have focused specifically on low-income women and minorities. The purpose of this study was to examine the validity of the Harvard Service FFQ (HSFFQ among low-income American Indian and Caucasian pregnant women. Methods The 100-item HSFFQ was administered three times to a sample of pregnant women, and two sets of 24-hour recalls (six total were collected at approximately 12 and 28 weeks of gestation. The sample included a total of 283 pregnant women who completed Phase 1 of the study and 246 women who completed Phase 2 of the study. Deattenuated Pearson correlation coefficients were used to compare intakes of 24 nutrients estimated from the second and third FFQ to average intakes estimated from the week-12 and week-28 sets of diet recalls. Results Deattenuated correlations ranged from 0.09 (polyunsaturated fat to 0.67 (calcium for Phase 1 and from 0.27 (sucrose to 0.63 (total fat for Phase 2. Average deattenuated correlations for the two phases were 0.48 and 0.47, similar to those reported among other groups of pregnant women. Conclusion The HSFFQ is a simple self-administered questionnaire that is useful in classifying low-income American Indian and Caucasian women according to relative dietary intake during pregnancy. Its use as a research tool in this population may provide important information about associations of nutrient intakes with pregnancy outcomes and may help to identify groups of women who would benefit most from nutritional interventions.
Rossi Maryann; Rodan Margaret F; White Davene B; Sharps Phyllis W; Milligan Renee A; Blake Susan M; Katz Kathy S; Murray Kennan B
Abstract Background African American women are at increased risk for poor pregnancy outcomes compared to other racial-ethnic groups. Single or multiple psychosocial and behavioral factors may contribute to this risk. Most interventions focus on singular risks. This paper describes the design, implementation, challenges faced, and acceptability of a behavioral counseling intervention for low income, pregnant African American women which integrated multiple targeted risks into a multi-component...
Full Text Available Abstract Smoking has been associated with several concerns in pregnancy including miscarriage, preterm delivery and stillbirth. Unfortunately, approximately 12% of the pregnant population continue to smoke cigarettes, suggesting a need for additional therapy beyond behavioural change. This paper reviews the literature on the use of nicotine replacement therapy and bupropion (Zyban® in the pregnant human population, the pharmacokinetics of nicotine in the pregnant woman, and current guidelines for smoking cessation for pregnant patients. There are currently four studies that have investigated the use of nicotine patch, three for nicotine gum, and registry and preliminary reports for bupropion. These studies did not show any adverse pregnancy outcomes with the use of pharmacological aid for smoking cessation. All the nicotine replacement therapy studies, with the exception of one randomized-controlled nicotine patch trial had small sample sizes and looked at short-term use of drug in the third trimester. Two studies have examined the pharmacokinetics of nicotine in the pregnant woman. The results from these studies reveal greater nicotine metabolism in pregnant individuals who continue to smoke during pregnancy. Current guidelines from several organizations uniformly recommend that Nicotine Replacement Therapy should be considered if non-pharmacological therapies have been unsuccessful. Bupropion is recommended in pregnancy if the benefits outweigh the risks. There is a need for further studies on the safety and effectiveness of Nicotine Replacement therapy and bupropion in pregnancy. However, considering the current research and guidelines, pharmacological cessation aids should be considered if non-pharmacological therapies have not been effective.
To study the relationship of leptin quantity of placenta, amniotic fluid, umbilical blood, maternal blood and newborn's weight, leptin levels of placenta, amniotic fluid, umbilical blood and maternal blood of 59 pregnant women were detected by RIA. Results were: (1) leptin was be detected from placenta, amniotic fluid, umbilical blood and maternal blood; (2) there was an obvious difference between leptin quantities of placenta, amniotic fluid, umbilical blood and maternal blood (P < 0.01); (3) there was an obvious difference between leptin quantities of placenta, amniotic fluid, umbilical blood and maternal blood for normal pregnant women and pregnancy induced hypertension (P < 0.01); (4) there was an obvious difference between leptin quantities of maternal blood and placenta (P < 0.01). It may be of important significance to detect eh leptin quantity of amniotic fluid and maternal blood in pregnant women for predicting the weight and growth of newborns and treat pregnancy induced hypertension
Simone Gonçalves Vasconcelos
Full Text Available The objective of the present investigation was to learn about the feelings experienced by HIV-infected pregnant women. This was a qualitative study carried out at a Maternity in Fortaleza, Brazil, from April to May 2005. Nine pregnant women who were aware of being infected with HIV were interviewed using guided questions. Data analysis was performed by reading and ordering the data, culminating in speech categorization. The data indicated that, when the pregnant women received a diagnosis of HIV infection they experienced episodes of sadness, anger and depression, but, with the passing of time, they looked for different strategies in order to cope with the disease. Pregnancy, even when unplanned, became something indispensable in their lives and represented not only encouragement and hope not to develop more advanced stages of the disease, but also a reason to overcome the social problems due to the infection.
Neiswanger, Katherine; McNeil, Daniel W.; Foxman, Betsy; Govil, Manika; Cooper, Margaret E.; Weyant, Robert J.; Shaffer, John R.; Crout, Richard J.; Simhan, Hyagriv N.; Beach, Scott R.; Chapman, Stella; Zovko, Jayme G.; Brown, Linda J.; Strotmeyer, Stephen J.; Maurer, Jennifer L.; Marazita, Mary L.
Background. Chronic poor oral health has a high prevalence in Appalachia, a large region in the eastern USA. The Center for Oral Health Research in Appalachia (COHRA) has been enrolling pregnant women and their babies since 2011 in the COHRA2 study of genetic, microbial, and environmental factors involved in oral health in Northern Appalachia. Methods. The COHRA2 protocol is presented in detail, including inclusion criteria (healthy, adult, pregnant, US Caucasian, English speaking, and nonimmunocompromised women), recruiting (two sites: Pittsburgh, Pennsylvania, and West Virginia, USA), assessments (demographic, medical, dental, psychosocial/behavioral, and oral microbial samples and DNA), timelines (longitudinal from pregnancy to young childhood), quality control, and retention rates. Results. Preliminary oral health and demographic data are presented in 727 pregnant women, half from the greater Pittsburgh region and half from West Virginia. Despite similar tooth brushing and flossing habits, COHRA2 women in West Virginia have significantly worse oral health than the Pittsburgh sample. Women from Pittsburgh are older and more educated and have less unemployment than the West Virginia sample. Conclusions. We observed different prevalence of oral health and demographic variables between pregnant women from West Virginia (primarily rural) and Pittsburgh (primarily urban). These observations suggest site-specific differences within Northern Appalachia that warrant future studies. PMID:26089906
Full Text Available Toxoplasmosis is a major public health problem among immuno-compromised individuals. This study aimed to determine the seroprevalence and associated risk factors of Toxoplasma gondii infection among pregnant women with and out HIV infections.This cross sectional study was conducted among consecutive 385 pregnant women attended Antenatal Clinic from May 2010 to October 2011 at the Gondar University Teaching Hospital, Northwest Ethiopia. Venous blood was collected from each pregnant woman for testing HIV-1/2 and anti- Toxoplasma antibodies using rapid test kits. Data were entered and analyzed using SPSS version 20 statistical package.The overall magnitude of T. gondii and HIV was 88.6% (341/385 and 11.2% (43/385, respectively. The seroprevalence of T. gondii was not different among HIV infected and non-infected pregnant women (88.4%, 38/ 43 vs 88.6%, 303/342. Keeping cats in house showed statistically significant association with seropositivity of toxoplasmosis (P<0.05.Irrespective of HIV infection, high rate of T. gondii was detected among pregnant women. These high prevalences indicate the need for an intensified public health awareness to reduce both infections.
Full Text Available OBJECTIVES: Determine the prevalence of asymptomatic urinary tract infection (AUTI among pregnant women. We also determined the antibacterial susceptibility of the isolates to various antibiotics and associated risk factors in AUTI. MATERIALS AND METHODS: One thousand five hundred and five consecutive pregnant women were included in the study. Mid-stream urine specimen for complete examination of urine was obtained. RESULTS: Of 1505 pregnant women, 134 (8.9% had bacteriuria. The mean age of the all the pregnant women included in the study was 28.40 years with a standard deviation of 6.16. Age ranged from 15 to 45 years of age. The urine culture of the asymptomatic pregnant women (1505 cases showed growth in only 134 cases (8.9%. Escherichia coli was the commonest organism 79 (58.96% followed by CN Staphylococcus 22 (16.8% and S aureus 18 (13.43%. Escherichia coli, which comprised 58.96% (79 of the isolates, were 88.62%, 87.35%, and 83.55% sensitive to cefotaxime, ciprofloxacin and cefotizoxime respectively. Similarly, E. coli were 89%, 70%, and 20% resistant to ampicillin, cotrimoxazole, and nitrofurantoin respectively (OR 1.57 95% CI 1.01, 2.44. After analyzing, four variables, hemoglobin levels seem to be independently associated with asymptomatic bacteriuria (OR = 9.41 (1.65-50.38. CONCLUSION: Prevalence of asymptomatic bacteriuria among pregnant women was 8.9%. The predominant organisms were Escherichia coli 79 (58.96%, followed by CN Staphylococcus 22 (16.8%. Most strains of Escherichia coli showed that they were resistant to ampicillin, tetracycline and gentamicin.
Kalantar, Enayat; Farhadifar, Fariba; Nikkho, Bahram.
Full Text Available OBJECTIVES: Determine the prevalence of asymptomatic urinary tract infection (AUTI) among pregnant women. We also determined the antibacterial susceptibility of the isolates to various antibiotics and associated risk factors in AUTI. MATERIALS AND METHODS: One thousand five hundred and five consecut [...] ive pregnant women were included in the study. Mid-stream urine specimen for complete examination of urine was obtained. RESULTS: Of 1505 pregnant women, 134 (8.9%) had bacteriuria. The mean age of the all the pregnant women included in the study was 28.40 years with a standard deviation of 6.16. Age ranged from 15 to 45 years of age. The urine culture of the asymptomatic pregnant women (1505 cases) showed growth in only 134 cases (8.9%). Escherichia coli was the commonest organism 79 (58.96%) followed by CN Staphylococcus 22 (16.8%) and S aureus 18 (13.43%). Escherichia coli, which comprised 58.96% (79) of the isolates, were 88.62%, 87.35%, and 83.55% sensitive to cefotaxime, ciprofloxacin and cefotizoxime respectively. Similarly, E. coli were 89%, 70%, and 20% resistant to ampicillin, cotrimoxazole, and nitrofurantoin respectively (OR 1.57 95% CI 1.01, 2.44). After analyzing, four variables, hemoglobin levels seem to be independently associated with asymptomatic bacteriuria (OR = 9.41 (1.65-50.38). CONCLUSION: Prevalence of asymptomatic bacteriuria among pregnant women was 8.9%. The predominant organisms were Escherichia coli 79 (58.96%), followed by CN Staphylococcus 22 (16.8%). Most strains of Escherichia coli showed that they were resistant to ampicillin, tetracycline and gentamicin.
Nor Azlin Mohamed Ismail
Full Text Available Background: Ramadan fasting for pregnant women with diabetes remains controversial and underreported. The objective of this study was to determine the glycemic control in pregnant diabetic women on insulin who fasted during Ramadan.Methods: This was a retrospective study carried out over a period of three years including pregnant diabetic women, who were on short-acting, intermediate-acting, or a combination of them, and opted to carry out Ramadan fasting. Glycemic control was assessed before, middle and after Ramadan fasting.Results: Thirty seven women opted to fast with 24 (64.9% of them had type 2 diabetes mellitus and 83.8% of them required combined insulin (short- acting, intermediate-acting therapy. The age of the participants was 32.13±4.68 years, and the age of their pregnancies was 25.60±7.12 weeks when the study was performed. The median number of days fasted was 25 days, and most of the women were able to fast for more than 15 days. There was no difference between glycemic control of type 2 diabetes mellitus and gestational diabetes mellitus women prior to fasting. In the middle of Ramadan, serum fructosamine decreased in both groups. However, only serum HbA1c reduced in gestational diabetes mellitus after Ramadan. Conclusion: the findings indicate that pregnant diabetic women on insulin were able to fast during Ramadan and that their glycemic control was improved during fasting period. They may also suggest that instead of absolute ban on fasting for pregnant diabetic women more practical approach and close consultation with health care providers might be more helpful.
Huygen, Kris; Caboré, Raïssa Nadège; Maertens, Kirsten; Van Damme, Pierre; Leuridan, Elke
Vaccination of pregnant women is recommended for some infectious diseases in order to protect both women and offspring through high titres of maternal IgG antibodies. Less is known on the triggering of cellular immune responses by vaccines administered during pregnancy. In an ongoing study on maternal pertussis vaccination (2012-2014) 18 pregnant women were vaccinated with a tetanus-diphtheria-acellular pertussis (Tdap) containing vaccine (Boostrix®) during the third pregnancy trimester. Sixteen age-matched nonpregnant women received the same vaccine in the same time period. A blood sample was taken at the moment of, but before vaccination and one month and one year after vaccination. Anti-Pertussis Toxin (PT), filamentous hemagglutinin (FHA), pertactin (Prn), tetanus toxin (TT) and diphtheria toxin (DT) antibodies were measured by ELISA. Cellular immune responses were analyzed using a diluted whole blood assay, measuring proliferation, and cytokine release in response to vaccine antigens PT, FHA, TT, and to pokeweed mitogen (PWM) as polyclonal stimulus. Antibody levels to all five vaccine components increased significantly and to the same extent after vaccination in pregnant and nonpregnant women. One year after vaccination, antibody titres had decreased particularly to PT, but they were still significantly higher to all antigens than before vaccination. In contrast, proliferative and IFN-? responses were increased to TT, PT, and FHA in nonpregnant women one month after vaccination, whereas in pregnant women only TT specific T cell responses were increased and to a lesser extent than in the control group. One year after vaccination, cellular responses equaled the baseline levels detected prior to vaccination in both groups. In conclusion, a Tdap vaccination can increase vaccine specific IgG antibodies to the same extent in pregnant and in nonpregnant women, whereas the stimulation of vaccine specific Th1 type cellular immune responses with this acellular vaccine is transient and impaired during pregnancy. PMID:26187257
Early and consistent intervention with pregnant smokers can reduce the incidence of adverse pregnancy outcomes associated with smoking during pregnancy. A survey of 470 pregnant women was conducted to establish the care they received in relation to smoking whilst attending routine public antenatal appointments. The overall prevalence of smoking was 23.5%. Age, level of education and nationality were associated with smoking status with younger, less educated Irish women being most likely to smoke. Women attending for their first visit were much more likely to be asked about their smoking status 71 (85.5) versus 68 (17.8) and advised to quit if they were smokers 11 (73.3) versus 11 (15.7). None of the women were offered specific assistance to help them stop smoking or had a follow-up appointment arranged specifically to do with smoking. 167 women (35.6) were exposed to passive smoking in their own homes.
Elahi, Shan; Hussain, Zaib
Problem Statement. Thyroid gland in women undergoes functional changes during pregnancy. A few studies have described such changes in pregnant women residing in iodine deficient areas. Objective. To document these changes in pregnant women residing in Lahore, a low iodine intake urban area of Pakistan. Patients and Methods. In 254 pregnant women, data of FT4, FT3, and TSH during the first and subsequent trimesters were obtained and compared with those of 110 nonpregnant women. These hormones were determined in serum by radioimmunoassay (RIA) techniques using commercial kits. Results. Compared to nonpregnant women mean FT4 level was decreased, and FT3 and TSH increased significantly (P Pregnancy is associated with significant alterations in thyroid function due to low iodine intake in women residing in study area. The compensated thyroid function poses a risk of thyroid failure in a number of pregnant women. PMID:24236234
The present study was performed to estimate the prevalence of HBV in pregnant women (mean age among groups 25,0 ± 6,9) who live in areas of different endemicity, and located in the Department of Lima, Junin, Apurimac, and Ayacucho in Peru. All studies were carried out using radioimmunological techniques. In the Instituto Materno Perinatal in Lima, located in a low endemic area, 2086 pregnant women whose ages ranged between 14 and 44 years old were evaluated (for laboratory tests) at their first prenatal examination. A prevalence of 0,38% (HBsAg+), 0,38% (Ratio), and 3,18% (HBsAg+, anti-HBsAg+) was found, corresponding to 107 HBsAg+ pregnant women whose treated newborn would prevent the HBV chronic infection of approximate 21 newborn each year. 63% HBsAg+ pregnant women were born in Departments other than Lima. In the Hospital de Apoyo La Merced, located in Chanchamayo, Junin, which is a medium endemic area, 217 pregnant women whose ages ranged between 14 and 48 years old were evaluated. T he prevalence found in this hospital was of 1,38% (HBsAg+), 1,2% (Ratio), and 17,*% (HBsAg+, anti-HBs+). All positive HBsAg were negative for HBeAg. The projection of results corresponded to a total of 9 HbsAg+ pregnant women and 2 newborn preventive of chronic disease per year. In the Guillermo Diaz de la Vega Hospital in Abancay, Apurimac, located in a medium to high endemic area, 221 pregnant women whose ages ranged between 15 and 46 years old were evaluated. A prevalence of 1,36% (HBsAg+), 1,0% (Ratio), and 36.16% (HBsAg+, anti-HBs+) was found. All positive HBsAg were negative for HBeAg. Projected results corresponded to a total of 37 HBsAg+ pregnant carriers and 7 newborn preventive of chronic disease per year. The Hospital General de Huanta, in Ayacucho, located in a high endemicity area, presented a prevalence of 3,2% (HBsAg+), 1,9% (Ratio), and 76, 2% (HBsAg+, anti-HBs+) from 126 pregnant women evaluated with ages between 15 and 48 years old. These results gave a total projection per year of 39 HBsAg+ pregnant women and 8 newborn preventive of chronic hepatic disease. Among a total of 4 positive HBsAg cases, 3 positive pregnant women were studied for HBeAg. All 3 were negative. These results establish the prevalence of HBsAg and antiHBs in pregnant women from different endemical areas with significant prevalence in the Departments of Ayacucho (Huanta), and Apurimac (Abancay). They also contribute towards the cost-benefit analysis for the prevention of HBV chronic infection
Full Text Available Abstract Background Hepatitis E virus (HEV, an enterically transmitted pathogen, is highly endemic in several African countries. Pregnant women are at particularly high risk for acute or severe hepatitis E. In Gabon, a central African country, the prevalence of antibodies to HEV among pregnant women is 14.1%. Recent studies have demonstrated unusual patterns of hepatitis E (chronic hepatitis, cirrhosis among immunodeficient patients. Findings We investigated the prevalence of antibodies to HEV among pregnant women infected with HIV-1 or HTLV-1 in Gabon. Of 243 samples collected, 183 were positive for HIV-1 and 60 for HTLV-1; 16 women (6.6% had IgG antibodies to HEV. The seroprevalence was higher among HIV-1-infected women (7.1% than HTLV-1-infected women (5.0%. Moreover, the HIV-1 viral load was significantly increased (p ? 0.02 among women with past-HEV exposure (1.3E+05 vs 5.7E+04 copies per ml, whereas no difference was found in HTLV-1 proviral load (9.0E+01 vs 1.1E+03 copies per ml. Conclusions These data provide evidence that HIV-1-infected women are at risk for acute or severe infection if they are exposed to HEV during pregnancy, with an increased viral load.
To evaluate the clinical significance of combined measurement of maternal serum free estriol (FE3) and human lactogen (HPL) for determination of intrauterine fetal growth and development. The serum FE3 and HPL in pregnant women were measured by chemiluminescence and RIA respectively. The results showed that the E3 and HPL levels in pregnant women with pregnancy induced hypertension were lower than the normal controls (P0.05). The combined measurement of maternal serum free estriol and human lactogen has important clinical significance in determination of fetus-placenta function and high risk pregnancy. (authors)
de Melo, Simone Cristina Castanho Sabaini; Gavena, Angela Andréia França; Silva, Flávia Teixeira Ribeiro; Moreira, Ricardo Castanho; de Lima Scodro, Regiane Bertin; Cardoso, Rosilene Fressatti; Siqueira, Vera Lúcia Dias; de Pádua, Rúbia Andreia Faleiros; Carvalho, Maria Dalva De Barros; PELLOSO, Sandra Marisa
Group B streptococcus (GBS), which commonly colonizes the female genital tract and rectum, can cause infections in newborns with varying severity, possibly leading to death. The aim of the present study was to evaluate Hitchens-Pike-Todd-Hewitt (HPTH) medium performance for GBS screening in pregnant women. A descriptive analytical cross-sectional study was performed with 556 pregnant women, of which 496 were at 35-37 weeks of gestation and 60 were at ? 38 weeks of gestation. The study was con...
Background: Availability of comprehensive family planning services is fundamental in improving and ensuring women’s right to life and health. An estimated 222 million women have an unmet need for contraception, and 43.8 million pregnancies are terminated each year, of which 21.6 million are considered to be unsafe and one of the main contributors to maternal mortality and morbidity. Medical abortion using misoprostol alone, or preferably the combined regimen of mifepristone and misoprostol, i...
Yasobant S, Nibedita S, Saswata S, Arnansu M, Kirti S
Full Text Available Background: Chronic medical conditions are in focus for the development of strategies aimed at improving population health worldwide. This is also true for chronic pain conditions leading to impaired or non-existent ability to exercise, as physical inactivity is associated with the development of chronic diseases. Musculoskeletal disorders constitute an estimated 90% of all chronic pain, of which back pain contributes to a high extent. During the time of pregnancy many hormonal and anatomical changes that affect the musculoskeletal system in the female body, which may cause various musculoskeletal complaints, predispose to injury, or alter the course of pre-existing conditions. Though Obstetric physiotherapy is an essential part of maternal health care and promotion; still it is not well known in developing countries like India. So this current study aimed to address common musculoskeletal complaints arising among the women during prenatal period in Odisha. Methodology: A cross sectional study was designed in rural & urban area health facilities targeting the pregnant women of Odisha. Total of 410 pregnant women from selected facilities of two different regions of Odisha- Eastern (Urban and Western (Rural were interviewed with a structured validated questionnaire. Statistical analysis compared the independent variables of participants with Musculoskeletal Pain using independent sample t-test for continuous variables and chi-square for ordinal/nominal variables has been reported considering null hypothesis to be significant if p-value is <0.05 which is level of significance. Results: About half (50.7% of the participants reported symptoms at least in one part of their bodies, over the pregnancy period. Among these, acute Low back pain was the highest of 55.6% and 35.4% of chronic, followed by acute ankle pain (25.9% and knee pain (16.6%. Neck pain (4.9%, Shoulder pain (4.4% were the least reported among all participants. The MSDs pain is more among the urban population (54.4%, compared to rural community (45.6%, which shows statistically significant with p-value of 0.003.Conclusion:Low back pain is the commonest of all, prevailing around more than half of subjects from our sample. A mixed research method strongly recommended to conduct, including both pre and post-natal period women, for generalizability and other facilities from all over the globe should be focused.
Jackson, Afton; Shannon, Lisa
The purpose of this study was to examine pregnant women's substance use from initial use, to recognition of problem severity, motivations for treatment, and ultimately to treatment entry. The sample consisted of 114 pregnant women receiving inpatient detoxification treatment at the University of Kentucky Chandler Medical Center. Qualitative and…
Full Text Available Abstract Background Estimating the seroprevalence of HIV in a low risk population such as pregnant women provides essential information for an effective implementation of AIDS control programmes, and also for the monitoring of HIV spread within a country. Very few studies are available from north India showing the current trend in HIV prevalence in the antenatal population;which led us to carry outthis study at a tertiary care hospital in north India Methods Blood samples from pregnant women attending antenatal clinics at the All India Institute of Medical Sciences, New Delhi were collected after informed consent and pre-test counseling. The samples were tested for HIV antibodies as per the WHO guidelines, over a period of four years from January 2003 to December 2006. Results Of the 3529 pregnant women tested in four years, 0.88% (CI 0.5 – 1.24 women were found to be HIV seroreactive. Majority of the seroreactive pregnant women (41.9% were in the age group of 20–24 years followed by the 30–34 yrs (25.8% and 25–29 years (22.6% age group. The mean age of the HIV positive women was 24.9 years (SD ± 1.49 yrs. The HIV seroprevalence rates showed an increasing trend from 0.7% (CI 0.14 – 2.04 in 2003–2004 to 0.9% (CI 0.49 – 1.5 in 2005–2006. This prevalence rate indicates concern, as Delhi and its adjoining states are otherwise considered as 'low prevalence states'. Conclusion Seroprevalence of HIV infection was found to be increasing in the last four years amongst pregnant women of North India. These findings are in contrast to the national projections.
Adeniran, Abiodun S.; Aboyeji, Abiodun P.; Fawole, Adegboyega A.; Balogun, Olayinka R.; Adesina, Kikelomo T.; Adeniran, Peace I.
Objectives To evaluate the expectations of pregnant women on the role of the male partner during conception and delivery. Methodology A prospective multi-centre observational study comprising 506 pregnant women at eight health facilities in Ilorin, Nigeria from January to June 2014. Consenting women were recruited at antenatal clinics using multistage purposive sampling and a self-administered questionnaire was administered with provision for interpreters in local dialects for those without western education. The data was analyzed using SPSS using percentages and chi-square test; p education (p=0.001) and parity less than four (p=0.001); religion (x21.010; p>0.001) and social status (p>0.001) were statistically insignificant. Pregnant women wanted education for male partners on care of pregnant women (77.0%) and sex during conception (25.2%). Conclusion Parturient desire male partners’ presence at deliveries but their past participation was low; health facility modifications and education for men are required to meet the desires. PMID:26609295
Objective: To investigate the variations of serum leptin levels in pregnant women of various trimesters and their neonates as well as the correlativity in-between. Methods: Serum leptin levels in 300 women at pregestation during the three trimesters and the umbilical blood leptin levels in their neonates were measured with RIA. Results: Serum leptin levels in pregnant women rose significantly only from midgestation with a peak at partum (p < 0.05 or p < 0.01 vs pregestation). The leptin levels in neonates were almost the same as those of women of pregestation. The maternal leptin levels were positively correlated to body weight, body weight-index, abdominal perimeter, height of fundus of uterus, diastolic and systolic pressure. The leptin levels in neonates were positively correlated to the birth weight, but not correlated to maternal leptin levels. Conclusion: Leptin in neonates comes from neonates themselves, and its concentrations are determined by the degree of accumulation of body adipose tissue. Measurement of blood leptin concentrations in pregnant women during pregnancy has little meaning for accessing the body weight of fetus, but it can show the degree of maternal weight-gaining and may have some value for clinical observation of the syndrome of pregnant hypertension
Full Text Available Protein Energy Malnutrition (PEM continues to be a major public health problem in developing countries and affects mostly infants, young children, pregnant and lactating mothers. This study was carried on some of the factors that predispose pregnant women to PEM and hence identify groups at greater risk. A total of 1387 pregnant women (910 in the urban area and 477 in the rural areas were recruited for the study. Anthropometric indices of weight, height and Body Mass Index (BMI of the pregnant women were measured and semi structured questionnaires were used to elicit information on possible predisposing factors such as age, level of education, parity, child spacing etc. Results obtained showed that the mean weight and height of the rural pregnant women, were significantly (p<0.0001 lower than those of the urban pregnant women. The mean BMI of the rural subjects, was also significantly (p< 0.0027 lower than that of the urban subjects. Analysis of the effect of age showed that the younger age category (24 years and below had significantly (p<0.0001 lower mean BMI and higher prevalence of PEM while the effect of level of education showed significantly (p<0006 lower mean BMI and higher PEM prevalence among the less educated (no formal and primary education. Those with parity of two, one and primipara showed significantly (p<0.0175 lower mean BMI while child spacing did not have any significant effect on both mean BMI and prevalence of PEM. The implications of these findings are discussed and recommendations made on how to tackle the problem.
Farnaz Fatemi; Parviz Pakzad; Hojjat Zeraati; Saeed Talebi; Soheila Asgari; Mohammad-Mehdi Akhondi; Leili Chamani-Tabriz
Objective(s)Rapid tests for detection of Streptococcus agalactiae or Group B Streptococci (GBS) at the onset of labor are needed to permit early intrapartum antibiotic prophylaxis. This study aimed to evaluate the PCR assays targeting the 16S ribosomal RNA gene (16S rDNA) for detection of the GBS in comparison with a specific culture method. Materials and MethodsTwo swabs were used to obtain vaginal specimens from the 330 pregnant women attended delivery room at Hedayat hospital, Tehran, Iran...
Eliane Cristina Hilberath Moreira
Full Text Available The period of gestation is considered a period of deep changes in the life of a woman. Thus, all the information and knowledge are necessary to lessen the anxieties and anguishes that occur in such period. It is essential an interdisciplinary service that focuses both the psychological and physical aspects in order to assist the pregnant woman in an overall manner. The objective of this study was to outline the profile of the pregnant women who took part of the “Pregnant Women´s Interdisciplinary Treatment Service” carried out at the Physiotherapy Clinic of Northern Paraná Regional University Hospital, Londrina, Paraná State, (HURNPr – UEL, and also to discuss about the use of physiotherapy techniques during the group therapies. Two questionnaires, formulated by the interdisciplinary team, were answered by the women, one in the first meeting and the other during the puerperal period. The target population consisted of 30 pregnant women, with ages between 16 and 42 years old, married, with High School level, workers, with family income superior to 10 minimum wages, first pregnancy and sedentary. The techniques learned in the course were used by just over half of the pregnant women. O período gestacional apresenta-se como um momento de profundas modificações na vida da mulher. Sendo assim, a informação e o conhecimento são necessários para diminuir as ansiedades e angústias que cercam esse período. É essencial um serviço interdisciplinar que aborde tanto os aspectos psicológicos quanto físicos para que se dê um atendimento global à gestante. O objetivo deste estudo foi traçar o perfil das participantes do “Serviço de Atendimento Interdisciplinar a Gestantes” desenvolvido no Ambulatório de Fisioterapia do Hospital Universitário Regional do Norte do Paraná – Universidade Estadual de Londrina (HURNPr-UEL e, também, discutir a utilização ou não das técnicas treinadas pela fisioterapia. Foram aplicados dois questionários formulados pela equipe interdisciplinar, um no primeiro encontro e outro no pós-parto. A população foi composta por 30 gestantes, com idades entre 16 e 42 anos, casadas, com nível de escolaridade, empregadas, com renda familiar superior a 10 salários mínimos, primigestas e sedentárias. Observa-se que as técnicas aprendidas no curso foram utilizadas por pouco mais da metade das gestantes.
Hajieh BiBi Shahbazian
Full Text Available Background & Objective: To determine the prevalence of gestational diabetes mellitus in pregnant women in Ahvaz Subjects and Methods: In this study, 678 pregnant women who had referred to two gynecologic and obstetrics clinics were evaluated. Screening was performed with 50 gram oral glucose challenge test (GCT with 140mg/dl cut-off point, and then a diagnostic 100g oral glucose tolerance test (OGTT was done according to Carpenter and Coustan criteria. Results: The prevalence of GDM and impaired glucose tolerance (IGT were 7.4% and 4.3%, respectively. The mean age of patients with GDM (30.32±5.27 years was obviously higher than that for healthy women (26.25±4.94 years (p<0.001.The average number of pregnancies of patients with GDM (2.4±1.1 was obviously higher than that for healthy women (1.9±1.1 (p<0.003. There was a significant difference between the number of previous abortion in women with GDM (30% and healthy women (13.85% (p= 0.002. The occurrence of previous GDM in women with GDM (10% was significantly higher than healthy women (33% (p = 0.0001. The frequency of previous macrosomia in women with GDM (6% and in women with IGT (10.34% were significantly higher than healthy women (0.5% (p= 0.003 and p< 0.001, respectively. There was no relationship between the prevalence of GDM and IGT with previous congenital abnormalities, previous still birth and number of parities. There was no relationship between the prevalence of IGT and the fallowing variables: the maternal age, number of pregnancies, previous abortion and previous GDM with prevalence of IGT. Conclusion:GDM has high prevalence in Ahvaz and screening is recommended for all pregnant women.
Kim, Hye Kyung; Niederdeppe, Jeff; Guillory, Jamie; Graham, Meredith; Olson, Christine; Gay, Geri
This study examined psychosocial and sociodemographic factors associated with pregnant women's use of Web-based tools to set and monitor personal goals for healthy diet and physical activity. These tools were made available to women participating in a randomized trial testing a Web-based intervention to promote appropriate gestational weight gain. We used data from a baseline survey of pregnant women assigned to the intervention group and log data on women's use of various intervention features (N = 873). Women who believed that appropriate gestational weight gain would lead to healthy outcomes for their child were more likely to engage in online goal-setting and self-monitoring. Less positive outcome expectancy beliefs about the relationship between their own weight and baby's health partially explains why some at risk subpopulations (e.g., African-American women) were less likely to utilize online self-regulatory tools. This study specifies key psychosocial and motivational factors that guide the construction and monitoring of goals among pregnant women. These findings offer guidance for the design of interventions to promote self-regulatory techniques by identifying groups for whom those features are most likely to be useful, as well as psychological determinants of their use. PMID:25205417
Saa'd, Sharon; Many, Ariel; Jacob, Giris; Ablin, Jacob N
The impact of fibromyalgia on the course of pregnancy is not clearly defined. We evaluate the frequency of FMS symptoms among full-term healthy pregnant women and the impact on the course of delivery. The 2011 modification of the ACR 2010 criteria for FMS diagnosis was used as well as the FIQ, SF-36 and AIMS questionnaires. The 1990 ACR classification criteria were documented. Data were collected relating to course of the delivery, induction, length of stage 1, 2 and 3 of delivery, epidural anesthesia, artificial rupture of membranes, instrumental delivery and cesarean section. A VAS recording pain intensity during delivery was documented. Out of 100 women recruited, 27 (27 %) fulfilled Modified FMS criteria. Only one of these women fulfilled ACR 1990 criteria, women who fulfilled the ACR criteria differed significantly from women who did not fulfill these criteria on a broad range of parameters including widespread pain and fatigue, social functioning, emotional well-being, role limitation and physical functioning. A significant correlation was found between length of stage 2 and results of the FIQ as well as with components of the SF-36. The intensity of pain during birth however was not correlated with the presence of FMS criteria. FMS symptoms were highly prevalent among healthy pregnant women at term. The presence of such symptoms may impact on the course of delivery and the need for anesthesia. Evaluating for features of centrally mediated pain may be of clinical relevance for physicians involved in the treatment of pregnant women. PMID:23263499
Full Text Available Abstract There is now considerable evidence for the involvement of K+ channels in nitric oxide (NO induced relaxation of smooth muscles including the myometrium. In order to assess whether apamin-sensitive K+ channels play a role in NO – induced relaxation of the human uterus, we have studied the effect of specific blockers of these channels on the relaxation of myometrium from non-pregnant women. In vitro isometric contractions were recorded in uterine tissues from non-pregnant premenopausal women who had undergone hysterectomy. Apamin (10 nM and scyllatoxin (10 nM did not alter spontaneous myometrial contractions. However, 15-min pretreatment of the myometrium strips with apamin completely inhibited relaxation caused by diethylamine-nitric oxide (DEA/NO. The pretreatment with scyllatoxin significantly reduced (about 2.6 times maximum relaxation of the strips induced by DEA/NO (p 2+ and voltage dependent charybdotoxin-sensitive (CTX-sensitive K+ channels, apamin-sensitive K+ channels are also present in the human non-pregnant myometrium. These channels offer an additional target in the development of new tocolytic agents.
Brett, MacLean; Rosanna F, Hess; Edward, Bonvillain; Joseph, Kamate; Daoda, Dao; Amy, Cosimano; Shannon, Hoy.
Full Text Available OBJECTIVES: To establish the rate of seroprevalence of the hepatitis B surface antigen in pregnant women in south-eastern Mali, and to decrease mother-to-child transmission. METHODS: In a descriptive cross-sectional comparison study, 3 659 pregnant women attending a non-governmental hospital in Kout [...] iala, Mali, during 2008 and 2009 were screened for the hepatitis B surface antigen during antenatal clinic attendance or when admitted for delivery. A chart review compared the hepatitis B virus (HBV)-positive women to HBV-negative women used as controls to identify potential risk factors for HBsAg positivity. The variables compared were age, parity, type of genital excision, birthweight of baby and HIV status. RESULTS: A total of 293 (8.0%) pregnant women tested positive for HBsAg. Their average age was 27.6 years, average parity of 2.8 births, 90% had Type 2 genital excision, 21% had low-birthweight infants, and 14 (0.4%) women also tested positive for HIV. Infants born to HbsAg-positive women were immunised with the hepatitis B vaccine in the delivery room. Two hundred and eighty-four HBVnegative women were compared with the HBV-positive women. None of the differences of means or relationships was statistically insignificant. CONCLUSION: In view of the high endemicity and lack of easily identifiable risk factors, free maternal HBV screening should be provided to all women in Mali, and the infants born to HBsAgpositive women should be immunised within 12 hours of birth.
Mozhgan Rabani Bavojdan
Full Text Available Objective: To evaluate sexual function and its relationship with quality of life, and mental and physical health in pregnant women.Materials and methods: Obtained results showed that 59 (39/3% pregnant women were "very dissatisfied", 25 (16/7% women were "moderately dissatisfied", 64 (42/7 % women were "both satisfied and unsatisfied", only 2 (1/3 % women were relatively satisfied, and no one was "very satisfied". There is a significantly negative weak correlation between female sexual function with anxiety and depression, while there is a significantly positive weak correlation between female sexual function with the general quality of life, psychological health and environment dimensions. Only depression predicts female sexual function significantly. The women more than 10 years passed of their marriage showed more sexual satisfaction compared to those less than 10 years passed of their marriage (p< 0.05.The roles of predictive variables in sexual dissatisfaction, as well as the limitations for the study are discussed in the article.Results: Obtained results showed that 59 (39/3% pregnant women were "very dissatisfied", 25 (16/7% women were "moderately dissatisfied", 64 (42/7 % women were "both satisfied and unsatisfied", only 2 (1/3 % women were relatively satisfied, and no one was "very satisfied". There is a significantly negative weak correlation between female sexual function with anxiety and depression, while there is a significantly positive weak correlation between female sexual function with the general quality of life, psychological health and environment dimensions. Only depression predicts female sexual function significantly. The women more than 10 years passed of their marriage showed more sexual satisfaction compared to those less than 10 years passed of their marriage (p< 0.05.The roles of predictive variables in sexual dissatisfaction, as well as the limitations for the study are discussed in the article.Conclusion: Depression as same as environment heath had an important effect on sexual satisfaction in pregnant women and so assessment of depression and environment health in medical program for pregnant women is necessary. Also considering decrease in sexual satisfaction in aging training new methods for sexuality can be useful.
Full Text Available To evaluate sexual function and its relationship with quality of life, and mental and physical health in pregnant women.Obtained results showed that 59 (39/3% pregnant women were "very dissatisfied", 25 (16/7% women were "moderately dissatisfied", 64 (42/7% women were "both satisfied and unsatisfied", only 2 (1/3% women were relatively satisfied, and no one was "very satisfied". There is a significantly negative weak correlation between female sexual function with anxiety and depression, while there is a significantly positive weak correlation between female sexual function with the general quality of life, psychological health and environment dimensions. Only depression predicts female sexual function significantly. The women more than 10 years passed of their marriage showed more sexual satisfaction compared to those less than 10 years passed of their marriage (p< 0.05. The roles of predictive variables in sexual dissatisfaction, as well as the limitations for the study are discussed in the article.Obtained results showed that 59 (39/3% pregnant women were "very dissatisfied", 25 (16/7% women were "moderately dissatisfied", 64 (42/7% women were "both satisfied and unsatisfied", only 2 (1/3% women were relatively satisfied, and no one was "very satisfied". There is a significantly negative weak correlation between female sexual function with anxiety and depression, while there is a significantly positive weak correlation between female sexual function with the general quality of life, psychological health and environment dimensions. Only depression predicts female sexual function significantly. The women more than 10 years passed of their marriage showed more sexual satisfaction compared to those less than 10 years passed of their marriage (p< 0.05. The roles of predictive variables in sexual dissatisfaction, as well as the limitations for the study are discussed in the article.Depression as same as environment heath had an important effect on sexual satisfaction in pregnant women and so assessment of depression and environment health in medical program for pregnant women is necessary. Also considering decrease in sexual satisfaction in aging training new methods for sexuality can be useful.
M. Nojomi Z. Akrami
Full Text Available Violence and the threat of violence against pregnant women are main barriers to women’s empowerment and equal participation in society. When stress and violence increase in developing societies, women’s safety in the home, workplace and community is often seriously affected. To determine the prevalence of physical abuse in pregnant women and to assess association between physical violence during pregnancy and maternal complications and birth outcomes, we used clinicbased data from a sample of 403 women who delivered live born infants during the summer of 2002 in our hospital. Data of physical violence against women’s during pregnancy and 3 months before that were based on questionnaire and interview. Outcomes data including antenatal hospitalization, labor and delivery complications were obtained from the records. Prevalence of physical violence during pregnancy was reported as 10.7%. Prevalence of experience of physical abuse 3 months before pregnancy was 11.9%. Women who experienced physical violence compared with those not reporting abuse were more likely to be smoker and hospitalized before delivery for maternal complications such as preterm labor, kidney infections, premature rupture of membranes and vaginal bleeding with pain. There was a significant association between physical violence and low birth weight and mother’s education. Physical violence during pregnancy is common and is associated with maternal complications and adverse birth outcomes. We suggest including methods to determine frequency of violence during pregnancy and assessment of violence in pregnancy by a screening program integrated in prenatal care.
Farias, P.; Borja-Aburto, V H; Rios, C.; Hertz-Picciotto, I.; Rojas-Lopez, M; Chavez-Ayala, R
This study examined the determinants of blood lead (BPb) in 513 pregnant women in Mexico City: 311 from public hospital prenatal clinics, representing primarily women of low socioeconomic status (SES), and 202 from private hospitals, primarily women of high SES. Overall, BPb levels ranged from 1.38 to 29 micrograms/dl, with geometric means of 6.7 and 11.12 micrograms/dl for women from private and public hospitals, respectively. The crude geometric means difference obtained by t-test was 4.42 ...
The decrease in the limits of dose equivalent at the entry of the abdomen of occupationally exposed pregnant women, as recommended by ICRP-60, necessitates to evaluate with dosimeter the various professional positions in different services existing in a health care centre, to guarantee that such limits cannot be exceeded, and thus ensure the protection of the foetus. The results obtained in this work, related exclusively to external radiation dose, show that the radiation protection system currently in force is in compliance with the regulation in the majority of the professional positions evaluated, though stricter criteria for pregnant women workers must be established with the aim of obtaining a better dose optimization. The fact that pregnant operators are working in Nuclear Medicine requires an additional effort to ensure that doses in excess of the limits stated are prevented
Introduction: In Western countries, about one pregnant woman in five experiences a considerable fear of childbirth (FOC). Consequently FOC is an important topic for midwives, being pregnant women’s main care givers. Also, although many aspects of FOC have been studied, almost no studies have into detail applied a theoretical frame of reference for studying pregnant women’s expectations for their upcoming labour and delivery. Therefore, the theory of self-efficacy, here regarding pregnant wome...
Hepworth, Sarah; Hardie, Laura; Fraser, Lorna; Burley, Victoria J.; Mijal, Renee; Wild, Christopher; Azad, Rafaq; McKinney, Patricia; Turner, Paul C.
Abstract Background Deoxynivalenol (DON) is a ubiquitous contaminant of cereal crops in temperate regions of the world. DON causes growth faltering and immune suppression in animals. Limited information is available on DON exposure in UK sub-populations. Objectives This study provides DON exposure assessment in a subset of pregnant women scheduled for an elective caesarean in a large multi-ethnic mother/infant birth cohort from Bradford, UK. Methods Women aged 16-44 years (n=85)...
Fatemi F; Chamani L; Pakzad P; Zeraati H; Rabbani H; Asgari S
Group B streptococci (GBS) or Streptococcus agalactiae are members of the normal flora of the female genital tract. GBS normally colonizes the vagina in many women asymptomatically. During labor this organism may infect the newborn, leading to neonatal sepsis and meningitis. This study aimed to investigate the prevalence of group B streptococcus in pregnant women by a rapid and easy culture method. It seems that in cases in which GBS carriage is not suspected until the time of labor, using su...
Full Text Available Abstract Background Toxoplasma gondii (T. gondii infection in pregnant women represents a risk for congenital disease. There is scarce information about the epidemiology of T. gondii infection in pregnant women in Mexico. Therefore, we sought to determine the prevalence of T. gondii infection and associated socio-demographic, clinical and behavioural characteristics in a population of pregnant women of Durango City, Mexico. Methods Three hundred and forty three women seeking prenatal care in a public hospital of Durango City in Mexico were examined for T. gondii infection. All women were tested for anti-T. gondii IgM and IgG antibodies by using IMx Toxo IgM and IMx Toxo IgG 2.0 kits (Abbott Laboratories, Abbott Park, IL, USA, respectively. Socio-demographic, clinical and behavioural characteristics from each participant were also obtained. Results Twenty one out of the 343 (6.1% women had IgG anti-T. gondii antibodies. None of the 343 women had IgM anti-T. gondii antibodies. Multivariate analysis using logic regression showed that T. gondii infection was associated with living in a house with soil floor (adjusted OR = 7.16; 95% CI: 1.39–36.84, residing outside of Durango State (adjusted OR = 4.25; 95% CI: 1.72–10.49, and turkey meat consumption (adjusted OR = 3.85; 95% CI: 1.30–11.44. Other characteristics as cat contact, gardening, and food preferences did not show any association with T. gondii infection. Conclusion The prevalence of T. gondii infection in pregnant women of Durango City is low as compared with those reported in other regions of Mexico and the majority of other countries. Poor housing conditions as soil floors, residing in other Mexican States, and turkey meat consumption might contribute to acquire T. gondii infection.
Winkel, C A; Milewich, L; Parker, C. R.; Gant, N F; Simpson, E. R.; MacDonald, P C
During the third trimester of human pregnancy the concentrations of deoxycorticosterone (DOC) in maternal plasma are 4-50 times those in nonpregnant women and men. It has been suggested that the increased amount of DOC in maternal plasma originates in the fetal compartment. We considered an alternate explanation for the high levels of DOC in plasma or near-term pregnant women, viz., that DOC may be derived in part from 21-hydroxylation of maternal plama progesterone. To test this hyposthesis ...
Lukasse, Mirjam; Schroll, Anne-Mette; Ryding, Elsa Lena; Campbell, Jacquelyn; Karro, Helle; Kristjansdottir, Hildur; Laanpere, Made; Steingrimsdottir, Thora; Tabor, Ann; Temmerman, Marleen; Van Parys, An-Sofie; Wangel, Anne-Marie; Schei, Berit
OBJECTIVES: The primary objective was to investigate the prevalence of a history of abuse among women attending routine antenatal care in six northern European countries. Second, we explored current suffering from reported abuse. DESIGN: A prospective cohort study. SETTING: Routine antenatal care in Belgium, Iceland, Denmark, Estonia, Norway, and Sweden between March 2008 and August 2010. POPULATION: A total of 7174 pregnant women. METHODS: A questionnaire including a validated instrument measur...
Rayis, Duria A
Abstract Background The increasing prevalence of obesity in young women is a major public health concern. Few data are available concerning the epidemiology of malnutrition especially obesity among pregnant women in the developing countries. A cross sectional study was conducted at Khartoum hospital during February-April 2008, to investigate prevalence of underweight, obesity, and to identify contemporary socio-demographic predictors for obesity among term pregnant women in Khartoum Hospital, Sudan. After taking an informed consent, a structured questionnaire was administered to each woman to gather information on educational level, age and parity. Maternal weight and height were measured and expressed as body mass index (BMI - weight (kg)\\/height (m) 2). Findings Out of 1690 term pregnant women, 628 (37.1%) were primigravidae, 926 (54.8%) had ? secondary educational level (minimum of 8 years) and 1445 (85.5%) were housewives. The mean (SD) of the age and parity were 27.2 (6.3) years and 2.0 (2.1) respectively. Out of these 1690 women, 94(5.5%) were underweight (BMI of ? 19.9 Kg\\/m2), 603 (35.6%) were overweight (BMI of 25 - 29.9 Kg\\/m2) and 328 (19.4%) were obese (BMI of ? 30 Kg\\/m2). In multivariate analyses, obesity was positively associated with age (OR = 1.2, 95% CI = 1.0-1.1; P< 0.001), and with women\\'s education (OR = 1.8, 95% CI = 1.2-2.7; P = 0.001). Obesity was positively associated with parity in univariate analyses only (OR = 1.1, 95% CI = 1.0-1.2; P = 0.02) Conclusion The high prevalence of obesity in these pregnant women represents a competing public health problem in Sudan. More research is needed.
In Sweden, there is currently no consensus addressing the screening, diagnostics and treatment of gestational diabetes mellitus (GDM). In addition, there is little knowledge on the impact of GDM on the daily life of pregnant women and the experiences of health care professionals providing maternal health care to women with GDM. Using different perspectives, this thesis examines the experiences of GDM and the performance of screening for GDM in a regional context in Sweden. The studies used qu...
Nancy Jallo; R. Jeanne Ruiz; R. K. Elswick; Elise French
The purpose of this study was to evaluate the efficacy of a guided imagery (GI) intervention for stress reduction in pregnant African American women beginning early in the second trimester. This prospective longitudinal study of 72 women used a randomized controlled experimental design with two groups conducted over 12 weeks. The intervention was a CD with 4 professionally recorded tracts designed and sequenced to influence study variables. Participants in both GI and usual care (UC) complete...
Ault, Kevin A; Burns, Barbara A.; Kennedy, Colleen M.
Background. This study was undertaken to determine whether rubella immunity infers measles immunity in pregnant women. Methods. Stored serum samples were obtained from the Iowa State Hygienic Laboratory for evaluation of rubella and measles immunities with IgG enzyme-linked immunosorbent assay. Results. Nine hundred serum samples were obtained for testing. The average age of the women at the time of antepartum serum collection was 28 (range, 14 to 44) years. Measles and ...
McIntyre H; Byrne Nuala M; Rowlands Ingrid J; Foxcroft¹ Katie F; Callaway Leonie K
Abstract Background Physical activity may reduce the risk of adverse maternal outcomes, yet there are very few studies that have examined the correlates of exercise amongst obese women during pregnancy. We examined which relevant sociodemographic, obstetric, and health behaviour variables and pregnancy symptoms were associated with exercise in a small sample of obese pregnant women. Methods This was a secondary analysis using data from an exercise intervention for the prevention of gestationa...
Full Text Available Background: A human immunodeficiency virus (HIV infection in pregnant women is an important medical challenge. There exist varied reports on the foeto-maternal outcome amongst HIV positive women in Africa. Aim: The study was to compare the foeto-maternal outcome among HIV-positive pregnant women who are on HAART with those that are HIV-negative. Methods: A comparative, case-control study of booked HIV-positive and HIV-negative women attending ante-natal clinic (ANC in Abuja. One hundred and five serial eligible HIV-positive women who booked for ante-natal care between October 8, 2012 and April 29, 2013 were recruited and matched with the control. They were followed up to six weeks post-partum. Live babies were tested for HIV using DNA polymerase chain reaction (PCR at six weeks post-partum. The data was analysed using statistical package for social science (SPSS version 16. Chisquare at < 0.05 at confidence level of 95% and Student t-test were used to determine significant association. Results: There were 112 HIV positive pregnant women among 1683 pregnant women during the study period giving a prevalence of 6.7%. The rate of preterm delivery was significantly higher among the HIV positive women (33% Vs 18%, P= 0.005. There was no case of vertical transmission. Conclusion: Maternal HIV infection was significantly associated with preterm delivery. There was no recorded vertical transmission. Strengthening the use of HAART may maintain zero vertical transmission among other precautionary measures.
Elenga, Narcisse; Hanf, Matthieu; Nacher, Mathieu
Background: The aim of this study was to identify the predictive factors of HIV disclosure to the sex partner in HIV pregnant women in Cayenne (French Guiana). Methods: A case control study was conducted including all deliveries in Cayenne from 2003 to 2010. For each case, a standardized questionnaire including epidemiological, clinical, and biological data was administered. Thirty-four women in the first group and 95 in the control group were included in the study. Results: The logistic regr...
Brooke, O. G.; Brown, I R; Bone, C D; Carter, N.D.; Cleeve, H J; Maxwell, J. D.; Robinson, V. P.; Winder, S M
In a double-blind trial of vitamin D supplements in pregnant Asian women calciferol (ergocalciferol, 1000 IU/day) was administered to 59 women and placebo to 67 controls during the last trimester. The two groups had similar distributions of maternal age, height, parity, number of vegetarians, countries of origin, and sex and gestation of the infants. At entry to the trial maternal serum 25-hydroxy vitamin D (25-OHD) concentrations were low in both treatment and control groups and significantl...
Soonthorndhada Kusol; Adhikari Ramesh; Prasartkul Pramote
Abstract Background Women living in every country, irrespective of its development status, have been facing the problem of unintended pregnancy. Unintended pregnancy is an important public health issue in both developing and developed countries because of its negative association with the social and health outcomes for both mothers and children. This study aims to determine the prevalence and the factors influencing unintended pregnancy among currently pregnant married women in Nepal. Methods...
Full Text Available Zhixian Sui,1 Jodie M Dodd1,21The University of Adelaide, Robinson Institute, Discipline of Obstetrics and Gynaecology, Women’s and Children’s Hospital, 2Department of Perinatal Medicine, Women’s and Babies Division, Women’s and Children’s Hospital, Adelaide, SA, AustraliaAbstract: Overweight and obesity have significant implications during pregnancy and childbirth. The objective of this review was to provide a comprehensive overview of the effect of physical activity on pregnancy outcomes, the change of physical activity during pregnancy, and women’s perception of being physically active during pregnancy, with a particular focus on women who are overweight or obese. Many studies have investigated the beneficial effect of exercise during pregnancy, including reduced risk of gestational diabetes, preeclampsia, and operative birth, in addition to improved cardiovascular function, overall fitness, psychological well-being, and mood stability. Benefits for the infant include reduced risks of prematurity and improved fetal growth, although there is more limited information about longer-term health benefits for both women and infants. The existing literature examining physical activity patterns during pregnancy has generally focused on women of all body mass index categories, consistently indicating a reduction in activity over the course of pregnancy. However, the available literature evaluating physical activity during pregnancy among women who are overweight or obese is more limited and contradictory. A number of studies identified barriers preventing women from being active during pregnancy, including pregnancy symptoms, lack of time, access to child care, and concerns about their safety and that of their unborn baby. Conversely, significant enablers included positive psychological feelings, family influence, and receiving advice from health professionals. Very few studies have provided insights about perceptions of being active during pregnancy in the overweight and obese population. There is a need for a detailed description of physical activity patterns during pregnancy in women who are overweight or obese, and more randomized trials evaluating exercise interventions for women who are overweight or obese, with a focus on clinical outcomes.Keywords: pregnancy, exercise, physical activity, overweight, obesity
Ayed H. Ziadat
Full Text Available air dye during pregnancy. The results of this study indicates that pregnant women who were dyeing their hair using at-home hair color dye had higher statistical frequencies of disabled children with more than one disability in comparison to mothers who have been dyeing their hair at hair salons by hair specialists.
Chan, Ko Ling; Brownridge, Douglas A.; Fong, Daniel Y. T.; Tiwari, Agnes; Leung, Wing Cheong; Ho, Pak Chung
Objective: To assess the impact of intimate partner violence (IPV) against pregnant women on subsequent perpetration of child abuse and neglect (CAN) by parents; and to test the mediation effect of recent IPV on the link between IPV during pregnancy and subsequent CAN. Methods: This study was a longitudinal follow-up of a population-based study on…
Vinter, Christina Anne; Tanvig, Mette Honnens; Damm, Peter; Naver, Klara Vinsand; Andreasen, Kirsten Riis; Andersen, Lise Lotte Torvin; Liest, Sara; Lunde, Søren Rasmussen; Jensen, Dorte Møller; Renault, Kristina Martha
One third of the pregnant Danish women are overweight or obese. Maternal obesity is an independent risk factor for adverse maternal and foetal outcomes including infertility, miscarriage, congenital malformations, preeclampsia, gestational diabetes, complicated deliveries, caesarean section, macrosomia and childhood obesity. This article reviews the effect of maternal obesity on obstetric and neonatal outcomes and provides recommendations for management of obesity in pregnancy.
Irina Vasilivna Tsyganenko; Vasil Vasilyovich Simrok; Katerina Sergiivna Ruban
The present article is concerned with the study of glial fibrillary acidic protein (GFAP) level in the blood serum of pregnant women with post–trauma brain injury syndrome (post-TBI syndrome) as the marker of hematoencephalic barrier status and predictor of obstetric and perinatal complications development.
Vinter, Christina Anne; Tanvig, Mette Honnens
One third of the pregnant Danish women are overweight or obese. Maternal obesity is an independent risk factor for adverse maternal and foetal outcomes including infertility, miscarriage, congenital malformations, preeclampsia, gestational diabetes, complicated deliveries, caesarean section, macrosomia and childhood obesity. This article reviews the effect of maternal obesity on obstetric and neonatal outcomes and provides recommendations for management of obesity in pregnancy.
Laurberg, Peter; Andersen, S.
Objective: To review methods for evaluating iodine deficiency in pregnant women and Young infants and to discuss factors to be considered in the interpretation of their results. Design: Review of the literature regarding the various methods available for assessing iodine status. Setting: Population Surveys and research studies. Subjects: Pregnant women and young infants. Results. Several factors to consider when assessing iodine status in pregnant women and young infants include: 1) the urinary iodine (UI) concentration (mu g l(-1)) is not interchangeable with 24 h UI excretion (mu g per 24 h); 2) the concentration of iodine in a spot or casual urine sample cannot be used to diagnose iodine deficiency in an individual; 3) a moderate fall in the concentration of serum free T4 during pregnancy is not a sign of maternal iodine deficiency; 4) an increase in the concentration of serum thyroglobulin (Tg) during pregnancy is not a sign of maternal iodine deficiency; 5) a higher concentration of TSH and Tg in cordblood than in maternal blood is not a sign of iodine deficiency in the mother or neonate; and 6) thyroid function in a full-term foetus, a neonate or a small child is not more sensitive to a mild iodine deficiency than in the mother. Conclusions: if the iodine status Of pregnant women and small children is not to be Misjudged, the above six factors need to be taken into account.
Full Text Available Background. The reproductive and sexual health issues concerning persons affected by thalassemia major are complex. The study was planned to investigate the psychological attitudes and expectations in a group of thalassemic pregnant women attending hospital for regular blood transfusion. Methods. The study included 20 consecutive thalassemic patients and a control group of 42 healthy pregnant volunteers. We evaluated the personality structure by Rorschach's test and the presence of psychic symptoms by SCL-90-R and STAI. Results. Narcissism and sexual traumas are significantly higher in thalassemic women with respects to the control group. Also the percent of anxiety and depression observed with the SCL-90-R was significantly higher than in control group. The score observed with the STAI shows that the state of anxiety changed significantly between thalassemic pregnant women and the control group, even though the scores values aren’t pathologic in neither group. Conclusions. This study addresses the need for developing, implementing and evaluating proper psychological support for thalassemic pregnant patients. The limit of this study is to analyze just thalassemic women because it doesn’t consider other pathologies; so the results can’t be extended to other pathologies different from thalassemic. Moreover, psychological screening and support prior to, during and following pregnancy would be indicated. Since not there are psychological studies in literature on the pregnancy in the thalassemic patients, the evaluation of the effects of pregnancy on the thalassemic disease will be the aim of future psychological investigations.
Stokholm, Jakob; Schjørring, Susanne; Pedersen, Louise; Bischoff, Anne Louise; Følsgaard, Nilofar; Carson, Charlotte G; Chawes, Bo; Bønnelykke, Klaus; Mølgaard, Anne; Krogfelt, Karen; Bisgaard, Hans
Furred pets in the household are known reservoirs for pathogenic bacteria, but it is not known if transmission of bacteria between pet and owner leads to significantly increased rate of infections. We studied whether cats and dogs living in the household of pregnant women affect the commensal vaginal flora, and furthermore the need for oral antibiotics and rate of urinary tract infections during pregnancy.
Bliddal, Sofie; Feldt-Rasmussen, Ulla; Boas, Malene; Faber, Jens; Juul, Anders; Larsen, Torben Kjeldgaard; Precht, Dorthe Hansen
Correct interpretation of thyroid status during pregnancy is vital to secure fetal development. Pregnancy-related changes in maternal thyroid status necessitate use of gestational-age-specific reference ranges. We investigated between-laboratory reproducibility of thyroid reference ranges in pregnant women.
Bentley, Kia J; Price, Sarah Kye; Cummings, Cory R
In their work in human services organizations and community agencies across service sectors, social workers encounter pregnant and postpartum women experiencing mental health challenges. This article offers an evidence-informed Decision Support Guide designed for use by social workers working with pregnant and postpartum women who are struggling with complicated decisions about psychiatric medication use. The guide is built on contemporary notions of health literacy and shared decision making and is informed by three areas: (1) research into the lived experiences of pregnant and postpartum women and health care providers around psychiatric medication decision making, (2) a critical review of existing decision aids, and (3) feedback on the strategy from social work practitioners who work with pregnant and postpartum women. Emphasizing the relational nature of social work in supporting effective health-related decision making, the guide relies on maintaining a collaborative practice milieu and using a decision aid that engages clients in discussions about mental health during and around the time of pregnancy. The guide offers social workers a practice tool to support responsive and compassionate care by embracing their roles in problem solving and decision making, providing emotional and psychosocial support, and making appropriate referrals to prescribers. PMID:25365831
Albright, Brittany; Skipper, Betty; Riley, Shawne; Wilhelm, Peggy; Rayburn, William F.
Objective: The study objective was to determine whether medical students' attendance at a rehabilitation residence for pregnant women with substance-use disorders yielded changes in their attitudes and comfort levels in providing care to this population. Methods: This randomized educational trial involved 96 consecutive medical students during…
Hayes, Catherine B
Systematic assessments of Motivational Interviewing (MI) in smoking behavior have been rare to date. This study aimed to determine whether an integrated approach, involving staff training in MI techniques, was sufficient to affect change in smoking status or intensity in low-income pregnant and postpartum women.
Although an excess of human adult blood adherent cells inhibits the pokeweed mitogen- (PWM) induced normal adult lymphocyte proliferation and B cell maturation into immunoglobulin-containing cells (ICC), adherent cells collected from newborn infants or pregnant women at time of delivery were unable to exert a similar suppressor activity. After activation by Concanavalin A (Con A), newborns' and pregnant women's adherent cells acquired a suppressor activity comparable to that of control adult adherent cells. The adherent suppressor cell was shown to be radioresistant (3000 rad), indicating its probable monocytic orgin. Both monocyte-suppressor activities (MSA) observed in adulthood (spontaneously) and in the neonatal period (after activation) were dependent on prostaglandin E2 (PGE2) secretion, because they were abolished by indomethacin or a specific anti-PGE2 anti-serum. Expression of MSA appeared to be under a negative regulation exerted by naturally occurring T suppressor lymphocytes present in the blood of newborns or pregnant women, because incubation of adult monocytes or Con A-activated newborn monocytes with newborns' or pregnant women's T lymphocytes resulted in a dramatic decrease of their MSA. These results strongly suggest that the lack of MSA in the neonatal period and in late pregnancy is a consequence of activation of T suppressor lymphocytes
Metabolic complications including diabetes mellitus have been increasingly recognised in HIV-infected individuals since the introduction of antiretroviral therapy, particularly protease inhibitors (PIs). Pregnancy is also a risk factor for impaired glucose metabolism, and previous studies have given conflicting results regarding the contribution of PIs to impaired glucose tolerance (IGT) and gestational diabetes mellitus (GDM) in pregnant HIV-infected women.
Jallo, Nancy; Salyer, Jeanne; Ruiz, R Jeanne; French, Elise
Maternal stress during pregnancy has been associated with numerous adverse pregnancy, birth, and health outcomes. Pregnant African American women have been reported to have higher levels of stress compared to other ethnic or racial groups underscoring the need for effective interventions to reduce stress in this population. The purpose of this study was to gain an in-depth understanding of the perceptions of guided imagery (GI) as a technique for stress management in a cohort of pregnant African American women who participated in a GI intervention as part of a larger mixed methods randomized controlled trial. The 12week intervention was a professionally recorded compact disc with four tracks developed and sequenced to reduce stress and associated symptoms. The findings from this descriptive phenomenologic study were derived from daily logs and interviews from 36 participants randomized to the GI group. Participants described the stressful nature of their lives. Results demonstrated pregnant African American women perceived the intervention as beneficial in reducing stress and the associated symptoms. The emergent themes suggested the intervention offered a respite from their stressful lives, reduced the negative emotional responses to stress and enhanced well-being, benefited other areas of their daily life, and provided an opportunity to connect with their baby. The study results support the perceived efficacy of GI as a stress coping intervention. GI is an economic as well as easy to implement, access and use technique that has potential stress coping benefits as perceived by pregnant African American women. PMID:26165981
Santacruz, A; Collado, M C; García-Valdés, L; Segura, M T; Martín-Lagos, J A; Anjos, T; Martí-Romero, M; Lopez, R M; Florido, J; Campoy, C; Sanz, Y
Obesity is associated with complications during pregnancy and increased health risks in the newborn. The objective of the present study was to establish possible relationships between gut microbiota, body weight, weight gain and biochemical parameters in pregnant women. Fifty pregnant women were classified according to their BMI in normal-weight (n 34) and overweight (n 16) groups. Gut microbiota composition was analysed by quantitative real-time PCR in faeces and biochemical parameters in plasma at 24 weeks of pregnancy. Reduced numbers of Bifidobacterium and Bacteroides and increased numbers of Staphylococcus, Enterobacteriaceae and Escherichia coli were detected in overweight compared with normal-weight pregnant women. E. coli numbers were higher in women with excessive weight gain than in women with normal weight gain during pregnancy, while Bifidobacterium and Akkermansia muciniphila showed an opposite trend. In the whole population, increased total bacteria and Staphylococcus numbers were related to increased plasma cholesterol levels. Increased Bacteroides numbers were related to increased HDL-cholesterol and folic acid levels, and reduced TAG levels. Increased Bifidobacterium numbers were related to increased folic acid levels. Increased Enterobacteriaceae and E. coli numbers were related to increased ferritin and reduced transferrin, while Bifidobacterium levels showed the opposite trend. Therefore, gut microbiota composition is related to body weight, weight gain and metabolic biomarkers during pregnancy, which might be of relevance to the management of the health of women and infants. PMID:20205964
Ockhuijsen, Henrietta D L; van den Hoogen, Agnes; Boivin, Jacky; Macklon, Nicholas S; de Boer, Fijgje
Pregnant women with a history of miscarriages experience symptoms of anxiety and depression in a subsequent pregnancy and are in need of support in the period after miscarriage, when trying to get pregnant again and during the first phase of pregnancy. The aim of this study was to investigate whether a Positive Reappraisal Coping Intervention (PRCI) and Daily Record Keeping (DRK) chart, developed for use in assisted conception treatment, are also appropriate for use in pregnant women with a history of miscarriage(s). In this convergent parallel mixed method study, thirteen women visiting an Early Pregnancy Unit and/or Recurrent Miscarriage Clinic in a university medical center in the Netherlands were selected on the basis of the number of miscarriages and age. Exclusion criteria were not speaking the Dutch language, pregnancy after fertility treatment and having a medical cause identified for the miscarriages. Women used the PRCI and DRK for 3weeks in a subsequent pregnancy. Quantitative data were obtained from the DRK and were analyzed by reporting frequencies and means for each case. Qualitative data were collected by semi-structured interviews and were analyzed by using thematic analysis. The majority of the women were able to use the PRCI and DRK for 3weeks. Women adapted the way in which they used the PRCI and DRK based on their judgment about the effect, the intensity of the emotions they experienced, or whether they felt the effort to use these instruments to be worthwhile or not. PMID:26608427
Tsering Chomu Dechen
Full Text Available Background: A study of genital colonization by group B streptococcus (GBS was conducted in pregnant women in their third trimester, which is a known risk factor of morbidity and mortality among newborns. Aims: The present study was undertaken to study the prevalence and the correlates of vaginal colonization by GBS among pregnant women. Setting and Design: This observational cross-sectional study was conducted during September 2002 to March 2004 on 524 pregnant women. Materials and Methods: Three high vaginal swabs were obtained from all the pregnant women admitted at term and in preterm labor. Two swabs were used for aerobic culture and the third one for gram staining. The first set of swabs was cultured on 5% Sheep blood agar plates. The second set of swabs were inoculated into Todd-Hewitt broth and then subcultured in 5% Sheep blood agar plates. The main outcome measures were the presence of GBS infection in comparison to the age group, gravida, gestational age, premature rupture of membrane (PROM, preterm labor and association with febrile spells of the present pregnancy. Results: The culture positivity rate of GBS was 4.77% and coexistent organisms isolated were Candida species (36%, Staphylococcus aureus (8% and Enterococcus species (8%. Culture positivity in the age group of 18-25 years was 5.71%, of which 5.74% were in their first pregnancy. The correlation between age group and gravida with GBS culture positivity was statistically insignificant. The culture positivity in <36 weeks of gestational age was 6.93%. This relation was statistically significant. Twenty-eight percent developed PROM. Sixty-four percent of culture positives had preterm labor. Conclusion: GBS infection among pregnant women was significantly correlated with the gestational age, PROM and preterm labor. In pregnancy GBS colonization causes asymptomatic bacteriuria or UTI. It is a well known cause of puerperal infections with amnionitis,endometritis and sepsis being the most commonly reported infections. [5
Full Text Available Abstract Background The aims of the present study were to determine the prevalence of toxoplasmosis in pregnant women at first trimester of their pregnancy and to follow up the seroconversion for next two trimesters, and to identify the risk factors and possible contamination routes in Aydin province, Turkey. Method The sample size was calculated as 423 on a prevalence of 50%, d=0.05 at a confidence level of 95% with 10% addition. It was a cross-sectional study with multistage sampling. After a questionnaire applied to the pregnant women, anti-Toxoplasma IgG antibodies were studied with ELISA and IFA, values in conflict with DA test, where IgM antibodies were studied with ELISA and for borderline or positive values of IgM avidity test was used. Results The mean age of 389 (92.9% of pregnant women in the study was 24.28+/-4.56 years, the seroprevalence of anti-Toxoplasma IgG antibodies for toxoplasmosis was 30.1%. Seroprevalence was increased with age (p=0.001 and with drinking water consumption other than bottled water (p=0.042. No significant relations were observed between anti-Toxoplasma IgG antibodies and education level, being native or migrant, abortion history, consumption of meat, vegetable and milk/milk products, personal or kitchen hygiene habits, cat owning at home of the pregnant women. No IgM antibody was detected. Conclusion One of every three pregnant women in Aydin was at risk of toxoplasmosis at the first trimester of their pregnancy. Increased seroprevalance with age was a predictable result because of increasing time of exposure. Increased seroprevalence with consumption of municipal and uncontrolled water (well/spring water supplies was similar with latest epidemiological findings.
Rogerio, Phili; Quarraisha A., Karim.
Full Text Available BACKGROUND: Studies on voluntary medical male circumcision (VMMC) have provided convincing evidence on its efficacy to provide partial protection against female-to-male HIV transmission in circumcised men. The World Health Organization and UNAIDS subsequently formulated recommendations for VMMC impl [...] ementation that included implementation of neonatal medical male circumcision (NMMC) to all infants up to two months old. Knowledge regarding the acceptability of NMMC by pregnant women who are candidates for granting of consents for NMMC procedures or its ideal placement within health programmes is low OBJECTIVES: We sought to establish NMMC acceptability by pregnant women and the feasibility of its integration within Maternal, Child and Women's Health (MCWH) programmes to inform implementation guidelines METHOD: Nurses and counsellors at two public health facilities were trained to provide NMMC counselling and offer NMMC to 1778 pregnant women presenting for antenatal care services. Univariate and bivariate analyses were performed on data collected on NMMC acceptance and refusals. Thematic analysis was also performed on qualitative reasons for refusals RESULTS: Acceptability of NMMC by women was high (82.9%). Refusals resulted from the need for consultations with partners and/or family members prior to consenting (41.3%), fear of the procedure (23.8%), cultural reasons (15.9%) and no reasons given (15.3%) CONCLUSION: The acceptability of NMMC by pregnant women and its integration with MCWH services was feasible. However socio-cultural factors, including the need for further consultation prior to consenting for NMMC procedures and preference of traditional circumcision by some women, need to be addressed in order to increase uptakes
A habit of eating clay soil especially among pregnant women is a common practice in Tanzania. This practice known as geophagy might introduce toxic elements in the consumer's body to endanger the health of the mother and her child. Therefore it is very important to have information on the elemental composition of the eaten soil so as to assess the safety nature of the habit. In this study 100 samples of clay soil, which were reported to be originating from five regions in Tanzania and are consumed by pregnant women were analyzed to determine their levels of essential and toxic elements. The analysis was carried out using energy dispersive X-ray fluorescent technique (EDXRF) of Tanzania Atomic Energy Commission, Arusha. Essential elements Fe, Zn, Cu, Se and Mn and toxic elements As, Pb, Co, Ni, U and Th were detected in concentrations above WHO permissible limits in some of the samples. The results from this study show that the habit of eating soil is exposing the pregnant mothers and their children to metal toxicity which is detrimental to their health. Hence, further actions should be taken to discourage the habit of eating soil at all levels. - Highlights: • We assessed exposure of heavy metals to pregnant mothers who consume geophagic soil. • We analyzed 100 samples of soil originated in Tanzania. • The technique used was energy dispersive X-ray fluorescent. • Essential and toxic elements were detected in concentrations above WHO limits. • Hence, geophagy is exposing pregnant mothers and their children to metal toxicity
Background: Syphilis, a sexually transmitted disease which seemed to have disappeared or had been controlled over the years, has now been re-emerged as a major public health problem in many communities. It can complicate the pregnancies with serious consequences. Appropriate treatment of pregnant women often prevents such complications. Aims: To study the frequency of syphilis in pregnant women attending a tertiary care public sector hospital, and see the positivity for HIV/AIDS among syphilis positive women. Patients and Methods: This cross sectional and interventional study was conducted among pregnant women attending Sir Ganga Ram hospital for antenatal care at PMRC Research Centre, Fatima Jinnah Medical College, Lahore. Blood samples from 2000 women were collected after taking consent. The blood was tested for syphilis by Treponema Pallidum Haemagglutination. History of the subjects for risks factors was also taken. Syphilis positive women were further screened for human immunodeficiency virus positivity. Results: The treponemal antibodies were detected in less than one percent (9) pregnant women. The highest positivity was observed among age group of 21-26 years. Women in third trimester were significantly more infected with syphilis. Risk factors included husband's history with frequent traveling and drug abuse. All husbands of syphilis positive women were also positive. All syphilis positive women and their husbands were negative for Human immunodeficiency virus /Acquired immune deficiency syndrome. Conclusions: Less than 1% of pregnant women were infected with syphilis, and most of the spouses of these positive women were either travelers or drug addicts.(author)
Elizabeth Hormann; Bellows, Anne C.; Qi Wang; Hans Konrad Biesalski; Veronika Scherbaum; Caroline K. Stiller; Haoyue Gao
Micronutrient deficiencies and imbalanced dietary intake tend to occur during the reproductive period among women in China. In accordance with traditional Chinese culture, pregnant women are commonly advised to follow a specific set of dietary precautions. The purpose of this study was to assess dietary intake data and identify risk factors for nutritional inadequacy in pregnant women from urban and rural areas of Deyang region, Sichuan province of China. Cross-sectional sampling was applied ...
Qiu Chunfang; Gelaye Bizu; Fida Neway; Williams Michelle A
Abstract Background Psychiatric disorders have been associated with sleep disorders in men and non-pregnant women, but little is known about sleep complaints and disorders among pregnant women with psychiatric disorders. Methods A cohort of 1,332 women was interviewed during early pregnancy. We ascertained psychiatric diagnosis status and collect information about sleep duration, daytime sleepiness, vital exhaustion and perceived stress. Logistic regression procedures were used to estimate od...
Pregnancy is a natural life of women in crisis. Pregnant women, during pregnancy important psychological, physiological and emotional changes live. These changes also affect body perceptions and subsequent self-respect. The purpose of this study, pregnant women and their self-esteem according to some variables to examine the perceptions of the body. The study was carried out using cross-sectional method. Sample of the study, between 15 March 2009 to 15 June 2009 Mayis University Medical Facul...
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Full Text Available Abstract Background Although studies have shown an association between anxiety and depression and obesity, psychological health among obese women during and after pregnancy has not been carefully studied. The aim of this study was to investigate psychological well-being using symptoms of depression and/or anxiety among obese pregnant women attending a weight gain restriction program and to then compare this group with a control group receiving traditional antenatal care. Methods 151 obese pregnant women in an intervention group and 188 obese pregnant women in a control group answered the Beck Anxiety Inventory (BAI and the Edinburgh Postnatal Depression Scale (EPDS. Group differences between the two groups were estimated by using the ?2 - test on categorical variables. The Student's t-test on continuous, normally distributed variables measuring changes in mean score on BAI and EPDS over time was used. To make a more comprehensive assessment of group differences, between as well as within the two groups, logistic regressions were performed with the BAI and EPDS as dependent variables, measured at gestational weeks 15 and 35 and 11 weeks postnatal. The grouping variable has been adjusted for socio-demographic variables and complications. Results The prevalence of symptoms of anxiety during pregnancy varied between 24% and 25% in the intervention group and 22% and 23% in the control group. The prevalence of symptoms of anxiety postnatally was 9% in the intervention group and 11% in the control group. Five percent of the women in the intervention group and 4% of the women in the control group showed symptoms of anxiety during the course of pregnancy and at the postpartum assessment. The prevalence of symptoms of depression during pregnancy varied between 19% and 22% in the intervention group but was constant at 18% in the control group. Postnatal prevalence was 11% in both groups. Six percent of the women in the intervention group and 4% in the control group showed symptoms of depression during the course of pregnancy and at the postpartum assessment. We found no differences between the two groups as concerns demographic characteristics, weight gain in kg, or the distribution of scores on anxiety and depressive symptoms nor did we find differences in the fluctuation of anxiety and depressive symptoms over time between the women in the intervention group and in the control group. Conclusion Obese pregnant women attending an intervention program seem to have the same risk of experiencing anxiety and/or depressive symptoms as do obese pregnant and postnatal women in general.
Sabers, Anne; Petrenaite, Vaiva
Previous studies have demonstrated that the pharmacokinetics of the new antiepileptic drug (AED) lamotrigine (LTG) are substantially influenced by pregnancy and are more likely to be associated with seizure deterioration in pregnancy compared to other AEDs. This is of great concern, as LTG has developed into a first-line AED for women of childbearing age. In this study we evaluated the risk of seizure deterioration in a cohort of women treated with LTG monotherapy (n = 42) who were closely monit...
McFarlane, J; Soeken, K; Campbell, J; Parker, B; Reel, S; Silva, C
To investigate the relationship between abuse to pregnant women and gun access by the abuser, an ethnically stratified cohort of 199 pregnant abused women (70 African-Americans, 63 non-Hispanic Anglo-American, and 66 Hispanic women were interviewed using: (1) The Index of Spouse Abuse, a measure of the severity of physical and nonphysical abuse; (2) The Danger Assessment Scale, a measure of potential danger of homicide; and (3) The Severity of Violence Against Women Scale, a measure of threats of violence and actual violence. There were no significant differences by ethnicity among the 41.2% of the abused women who reported that their male partner had access to a gun. Among these same women reporting gun access, 17% reported the abuser kept the gun on his body. Women reporting gun access by the abuser reported higher level of abuse on all scaled instruments (P = gun access is recommended. Additionally, policy initiatives to remove firearms from abuse perpetrators may reduce the severity of violence experienced by abused women. PMID:9629034
Rydbeck, Filip; Bottai, Matteo; Tofail, Fahmida; Persson, Lars-Åke; Kippler, Maria
Iodine is an essential dietary element required for normal fetal growth and development. We aimed to explore intraindividual and interindividual variations in iodine intake in pregnant women and whether non-dietary factors might influence the intake. Iodine intake was assessed in 271 women, residing in Matlab, rural Bangladesh, by measuring their urinary iodine concentration (UIC) at gestational week (GW) 8, 14, 19, and 30 with inductively coupled plasma mass spectrometry. The women's UIC increased significantly during pregnancy (median 241 (GW8) and 300??g/l (GW30)). About 6% of the women had insufficient iodine intake (UICiodine intake (UIC?500??g/l) at all of their four sampling occasions. The women's UIC were dependent on their education, socio-economic status, and BMI, as well as the season of sampling and iodine concentrations in drinking water. Supplementation with a multi-micronutrient capsule, including 150??g potassium iodine, increased the UIC in women with the lowest UIC (10th percentile) at GW30 but decreased the UIC in women with the highest UIC (90th percentile) at GW30. In conclusion, median UIC throughout pregnancy indicated adequate intake of iodine among pregnant women in Matlab, but, notably, consistently insufficient and excessive intake was also prevalent. PMID:24220214
Yeo, Seonae; Logan, Jeongok G
Low-income women are at risk for excessive gestational weight gain. Inactive lifestyle and lack of regular moderate exercise may contribute to the risk of weight gain. This study was conducted to (1) determine the rate and characteristics of low-income pregnant women who exercised regularly and met the American College of Obstetricians and Gynecologists recommendation and (2) describe how these women spent time for other physical activities compared with those who did not exercise regularly. Medicaid-recipient or uninsured pregnant women (n = 816) were asked to complete a physical activity questionnaire at rural and urban county health departments located in North Carolina. Twenty percent of low-income women met the American College of Obstetricians and Gynecologists recommendation for moderate exercise (?10 METs-h/wk [metabolic equivalent task-hours per week]). The women who met the recommendation spent 3 hours 45 minutes per week walking as exercise, whereas those who did not meet the recommendation spent 1 hour per week (P exercised regularly spent longer hours at work (4.25 vs. 1.75 hours per day; P = .019) and on household tasks (5.25 vs. 4.0 hours per day; P = .002) than women who did not exercise regularly. Time spent on domestic and occupation activities does not seem to prohibit low-income women from engaging in moderate exercise on a regular basis. PMID:24476648
Rendell, Victoria R.; Gilman, Robert H.; Valencia, Edward; Galdos-Cardenas, Gerson; Verastegui, Manuela; Sanchez, Leny; Acosta, Janet; Sanchez, Gerardo; Ferrufino, Lisbeth; LaFuente, Carlos; Abastoflor, Maria del Carmen; Colanzi, Rony; Bern, Caryn
Background Congenital transmission is a major source of new Trypanosoma cruzi infections, and as vector and blood bank control continue to improve, the proportion due to congenital infection will grow. A major unanswered question is why reported transmission rates from T. cruzi-infected mothers vary so widely among study populations. Women with high parasite loads during pregnancy are more likely to transmit to their infants, but the factors that govern maternal parasite load are largely unknown. Better understanding of these factors could enable prioritization of screening programs to target women most at risk of transmission to their infants. Methodology/Principal Findings We screened pregnant women presenting for delivery in a large urban hospital in Bolivia and followed infants of infected women for congenital Chagas disease. Of 596 women screened, 128 (21.5%) had confirmed T. cruzi infection; transmission occurred from 15 (11.7%) infected women to their infants. Parasite loads were significantly higher among women who transmitted compared to those who did not. Congenital transmission occurred from 31.3% (9/29), 15.4% (4/26) and 0% (0/62) of women with high, moderate and low parasite load, respectively (?x2 for trend 18.2; p<0.0001). Twin births were associated with higher transmission risk and higher maternal parasite loads. Infected women without reported vector exposure had significantly higher parasite loads than those who had lived in an infested house (median 26.4 vs 0 parasites/mL; p<0.001) with an inverse relationship between years of living in an infested house and parasite load. Conclusions/Significance We hypothesize that sustained vector-borne parasite exposure and repeated superinfection by T. cruzi may act as an immune booster, allowing women to maintain effective control of the parasite despite the down-regulation of late pregnancy. PMID:25807498
Full Text Available Abstract Background Women who have a breech presentation at term have to decide whether to attempt external cephalic version (ECV and how they want to give birth if the baby remains breech, either by planned caesarean section (CS or vaginal breech birth. The aim of this study was to explore the attitudes of women with a breech presentation and health professionals who manage breech presentation to ECV. Methods We carried out semi-structured interviews with pregnant women with a breech presentation (n=11 and health professionals who manage breech presentation (n=11 recruited from two hospitals in North East England. We used purposive sampling to include women who chose ECV and women who chose planned CS. We analysed data using thematic analysis, comparing between individuals and seeking out disconfirming cases. Results Four main themes emerged from the data collected during interviews with pregnant women with a breech presentation: ECV as a means of enabling natural birth; concerns about ECV; lay and professional accounts of ECV; and breech presentation as a means of choosing planned CS. Some women’s attitudes to ECV were affected by their preferences for how to give birth. Other women chose CS because ECV was not acceptable to them. Two main themes emerged from the interview data about health professionals’ attitudes towards ECV: directive counselling and attitudes towards lay beliefs about ECV and breech presentation. Conclusions Women had a range of attitudes to ECV informed by their preferences for how to give birth; the acceptability of ECV to them; and lay accounts of ECV, which were frequently negative. Most professionals described having a preference for ECV and reported directively counselling women to choose it. Some professionals were dismissive of lay beliefs about ECV. Some key challenges for shared decision making about breech presentation were identified: health professionals counselling women directively about ECV and the differences between evidence-based information about ECV and lay beliefs. To address these challenges a number of approaches will be required.
Mingle Julius AA
Full Text Available Abstract Background Hepatitis E virus (HEV is highly endemic in several African countries with high mortality rate among pregnant women. The prevalence of antibodies to HEV in Ghana is not known. Therefore we evaluated the prevalence of anti-HEV IgG and anti-HEV IgM among pregnant women seen between the months of January and May, 2008 at the Obstetrics and Gynaecology Department, Korle-Bu Teaching Hospital, Accra, Ghana. Results One hundred and fifty-seven women provided blood samples for unlinked anonymous testing for the presence of antibodies to HEV. The median age of participants was 28.89 ± 5.76 years (range 13–42 years. Of the 157 women tested, HEV seroprevelance was 28.66% (45/157. Among the seropositive women, 64.40% (29/45 tested positive for anti-HEV IgM while 35.60% (16/45 tested positive to HEV IgG antibodies. HEV seroprevalence was highest (46.15% among women 21–25 years of age, followed by 42.82% in = 20 year group, then 36.84% in = 36 year group. Of the 157 women, 75.79% and 22.92% were in their third and second trimesters of pregnancy, respectively. Anti-HEV antibodies detected in women in their third trimester of pregnancy (30.25% was significantly higher, P Conclusion Consistent with similar studies worldwide, the results of our studies revealed a high prevalence of HEV infection in pregnant women.
Goumba Charles M
Full Text Available Abstract Background Hepatitis E virus (HEV is a major public health problem in developing countries. HEV infection in pregnant women is more common and more often fatal in the third trimester. The mortality rate due to HEV-induced hepatitis is as high as 15-20 per cent. The present study was designed to determine the potential factors responsible for high mortality rate among pregnant women. Findings Twenty one pregnant women attended the Maternity Center of Begoua in the Central African Republic during an outbreak of hepatitis E virus between July and October 2002 with symptoms of acute liver disease. Their mean gestational period was 29.9 (SD 8.3 weeks and they were aged from 15 to 39 years old. The serology IgM showed that seven women (33% had acute hepatitis E. Among them, one woman, aged 35 and her newborn died after an apparently normal preterm delivery. The 6 remaining young women, age 18 - 22, had preterm deliveries which included three live babies and three stillborn with one macerated. Conclusions These results suggest that maternal age, in addition to hormonal, immunological and environmental factors, may be a risk factor for fatal outcome.
Fatemeh Davari Tanha
Full Text Available To evaluate physical activity of pregnant women before and after ACOG guideline study. Four hundred and eighty-five pregnant women enrolled in this before-after study. They were asked to study ACOG guideline. A structured questionnaire filled by women at first visit and the last visit in the prenatal clinic.Type, frequency, duration and anxiety about doing exercises during pregnancy period. Before education, 411 did exercises before pregnancy onset, among them, 346 were walking out and 65 did light exercises such as aerobics. After studying the protocol, 434 (89.4% did walking during pregnancy period in comparison to 71% who did walking before pregnancy (P<0.001. Forty two (56.7% out of 74 who had not done sport before, went for walking after the protocol reading, and nine continued not doing exercise. Among 74 participants who had not done exercise before the protocol reading, 16 (21% were doing exercise three times a week and 11 (14% changed their habit to daily exercise practice (P<0.001. Forty percent (195 women were anxious about doing exercise during pregnancy before guideline study, while 116 reported that after the protocol reading, they had no anxiety about doing exercises during pregnancy (P<0.001. Guidelines providing information about physical activity during pregnancy will help pregnant women to do exercise during pregnancy with convenience and less anxiety.
Full Text Available Under supervision there were 233 pregnant women with excessive weight aged 18-43 years. Patients were under observation and gave birth on the basis of obstetric units of municipal establishment "Dnepropetrovsk regional perinatal center with in-patient unit of" Dnepropetrovsk regional council". When performing research 2 groups were formed: 120 (51,5% pregnant women with miscarriage threat against excessive weight being at in-patient treatment since early terms of pregnancy. They underwent in-depth study. 113 (48,5% pregnant women with obesity with gestation course estimated retrospectively at the time of delivery. As a result of the obtained data in women of prospective group treatment algorithm was developed. This algorithm represented a complex treatment including antiagregant and anticoagulant therapy, co-factor vitamin therapy. Despite a more mature age of women of prospective group, adverse anamnesis by missarriage, high frequency of miscarriage in its first half, low placentation level, this complex allowed to improve course of the second half of pregnancy and to reduce number of gestational complications and perinatal losses.
Kedir, Haji; Berhane, Yemane; Worku, Alemayehu
Background. Iodine deficiency in pregnancy is a worldwide problem. This study aimed to assess prevalence and predictors of subclinical iodine deficiency among pregnant women in Haramaya district, eastern Ethiopia. Methods. A cross-sectional, community-based study was conducted on 435 pregnant women existing in ten randomly selected rural kebeles (kebele is the smallest administrative unit in Ethiopia). Data on the study subjects' background characteristics, dietary habits, and gynecological/obstetric histories were collected via a structured questionnaire. UIC of iodine deficiency. Data were analyzed by Stata 11. A multivariable logistic regression was used to identify the predictors of subclinical iodine deficiency. Results. The median urinary iodine concentration (MUIC) was 58.1??g/L and 82.8% of the women who had subclinical iodine deficiency. The risk of subclinical iodine deficiency was reduced by the use of iodized salt (AOR = 0.13) and by intake of milk twice a month or more (AOR = 0.50), but it was increased by maternal illiteracy (AOR = 3.52). Conclusion. Iodine nutritional status of the pregnant women was poor. This shows that women and their children are exposed to iodine deficiency and its adverse effects. Thus, they need urgent supplementation with iodine and improved access to and intake of iodized salt and milk during pregnancy. PMID:25132987
To determine the frequency of vaginal candidiasis in clinically symptomatic and asymptomatic cases of pregnant women attending routine antenatal clinic. A total of 110 pregnant women were nonrandomly recruited by convenient sampling. The studied variables included the demographic data information on parity, trimester of pregnancy, presence of vaginal discharge and the presence or absence of diabetes. Vulva and vagina were inspected for signs of inflammation and discharge with sterile speculum and vaginal specimens were collected with sterile cotton tipped swabs. Swabs were subjected to Gram staining and examined microscopically for the diagnosis of candidiasis. The frequency of vaginal candidiasis during pregnancy was found to be 38%, in which 27% were symptomatic and 11% were asymptomatic group. Increased ratio of infection was observed in multigravida and diabetic women. There was no marked differences in results with respect to age and trimester of pregnancy. Although there is generally a high frequency of vaginal candidiasis, an increased ratio of vaginal candidiasis in multigravida and diabetic pregnant women requires these women to be routinely screened for vaginal candidiasis regardless of symptomatic status. (author)
Rosiléia Marinho de, Quadros; Gino Chaves da, Rocha; Getúlio, Romagna; Juliana Pellizzoni de, Oliveira; Dadryhan Morghani, Ribeiro; Sandra Márcia Tietz, Marques.
Full Text Available INTRODUCTION : Toxoplasmosis is a zoonotic infection caused by Toxoplasma gondii. It is transmitted by the ingestion of contaminated water and foods, by soil contaminated with cat feces, especially while handling it, and congenitally via the placenta. The diagnosis of maternal infection is made by [...] serological detection of either IgM or IgG antibodies. This study assessed the seropositivity in pregnant women followed up by the Family Health Strategy (FHS) in Lages, Santa Catarina, Brazil. METHODS: The study was performed in 19 FHS units and included 148 childbearing women. The outcomes evaluated were IgM and IgG seropositivity and behavioral variables. RESULTS: IgG yielded positive results in 16% of the pregnant women, whereas IgM was positive in only 1%. CONCLUSIONS: The 1% IgM positivity rate for T. gondii indicates congenital toxoplasmosis is not common in Lages.
In a survey it will be given results of consultations of pregnant women exposed during the pregnancy in the period of 1976 to 1992 formerly in the National Board of Atomic Safety and Radiation Protection of the GDR and since 1990 in the Clinic-diagnostical Division of the Federal Health Office. The report includes dose estimations of the embryo and medical assessments of 430 pregnant women. The radiation exposure were mainly received by X-ray diagnostic (n = 406 cases) and the others by applications of radiation in nuclear medicine, research and vocational training (n = 24 cases). Results of dose and risk estimation were summarized in tables. Women having incurred fetal doses in excess of 100 mGy were recommended to interrupt pregnancy. A fetal dose above 100 mGy occured in 9 cases. The anatomico-pathological and embryological findings of the embryo or fetus showed only in one case a reference of teratogenic radiation damage. (orig.)
Surgers, L; Bleibtreu, A; Burdet, C; Clermont, O; Laouénan, C; Lefort, A; Mentré, F; Carbonne, B; Bingen, E; Meynard, J-L; Denamur, E
In order to improve knowledge on Escherichia coli bacteraemia during pregnancy, we studied clinical data and performed molecular characterization of strains for 29 E. coli bacteraemia occurring in pregnant women. Bacteraemia mostly occurred in the third trimester of pregnancy (45%) and was community-acquired (79%). Portals of entry were urinary (55%) and genital (45%). E. coli strains belonged mainly to phylogroups B2 (72%) and D (17%). Four clonal lineages (i.e. sequence type complex (STc) 73, STc95, STc12 and STc69) represented 65% of the strains. The strains exhibited a high number of virulence factor coding genes (10 (3-16)). Six foetuses died (27%), five of them due to bacteraemia of genital origin (83%). Foetal deaths occurred despite adequate antibiotic regimens. Strains associated with foetal mortality had fewer virulence factors (8 (6-10)) than strains involved in no foetal mortality (11 (4-12)) (p 0.02). When comparing E. coli strains involved in bacteraemia with a urinary portal of entry in non-immunocompromised pregnant vs. non-immunocompromised non-pregnant women from the COLIBAFI study, there was no significant difference of phylogroups and virulence factor coding genes. These results show that E. coli bacteraemia in pregnant women involve few highly virulent clones but that severity, represented by foetal death, is mainly related to bacteraemia of genital origin. PMID:24979689
Brenning, Katrijn; Soenens, Bart; Vansteenkiste, Maarten
Prenatal psychological adjustment is a critical predictor of postnatal maternal adjustment, which, in turn, relates to a child's psychological development. As such, it is important to examine possible correlates of women's psychological functioning during pregnancy. Grounded in self-determination theory (Deci & Ryan, 2000), the present research investigated the link between women's motives for having a child and prenatal maternal psychological adjustment. Specifically, in a sample of 208 pregnant women, we examined the relation between women's intensity (i.e., quantity) and quality of motivation for having a child and both women's social adjustment (i.e., relationship satisfaction) and personal well-being (i.e., vitality and depressive symptoms). Further, we examined psychological need satisfaction as an explanatory mechanism underlying these associations. Results showed that both intensity and quality of motivation related, either directly or indirectly via psychological need satisfaction, to women's personal well-being and relationship satisfaction during pregnancy. (PsycINFO Database Record PMID:26147933
Steenwinkel, F.D.O.; Tak, H.V.; Muller, A. F.; Nouwen, J. L.; Oostvogel, P.M.; Mocumbi, S.M.
The prevalence of group B streptococcus (GBS) carriage varies strongly with geographical region. A study was done to determine the prevalence of GBS in women in Maputo, Mozambique. The method used was a rectovaginal swab which was taken from women between 35 and 37 weeks of pregnancy who visited the clinic for antenatal consultation. GBS was cultured from 2 out of 113 samples, yielding a prevalence of 1.8% (95% Cl: 0.0-4.0). In conclusion, the prevalence of GBS carriage among pregnant women i...
Diab Tayseer E
Full Text Available Abstract Background The increasing prevalence of obesity in young women is a major public health concern. Few data are available concerning the epidemiology of malnutrition especially obesity among pregnant women in the developing countries. A cross sectional study was conducted at Khartoum hospital during February-April 2008, to investigate prevalence of underweight, obesity, and to identify contemporary socio-demographic predictors for obesity among term pregnant women in Khartoum Hospital, Sudan. After taking an informed consent, a structured questionnaire was administered to each woman to gather information on educational level, age and parity. Maternal weight and height were measured and expressed as body mass index (BMI - weight (kg/height (m 2. Findings Out of 1690 term pregnant women, 628 (37.1% were primigravidae, 926 (54.8% had ? secondary educational level (minimum of 8 years and 1445 (85.5% were housewives. The mean (SD of the age and parity were 27.2 (6.3 years and 2.0 (2.1 respectively. Out of these 1690 women, 94(5.5% were underweight (BMI of ? 19.9 Kg/m2, 603 (35.6% were overweight (BMI of 25 - 29.9 Kg/m2 and 328 (19.4% were obese (BMI of ? 30 Kg/m2. In multivariate analyses, obesity was positively associated with age (OR = 1.2, 95% CI = 1.0-1.1; PP = 0.001. Obesity was positively associated with parity in univariate analyses only (OR = 1.1, 95% CI = 1.0-1.2; P = 0.02 Conclusion The high prevalence of obesity in these pregnant women represents a competing public health problem in Sudan. More research is needed.
To elaborate the relationship between serum homocysteine (hcy) levels and vascular related pregnancy complications in pregnant women as well as to assess the homocysteine lowering effects of folate, vitamin B12 and B6. The secondary objectives were to establish a link between serum homocysteine levels and maternal age, parity, gestational age, foetal birth weight, mean arterial pressure and albuminuria. Methods: A total of 332 pregnant women (gestational age: >24 weeks) attending Liaquat University Hospital Hyderabad, Pakistan, were enrolled. Of these 112 were healthy normal pregnant women; 61 pregnant women had pre-eclampsia, 49 with eclampsia and 110 with placental abruption. A cohort of 30 patients with elevated hcy levels (>8.2 mu mol/liter), were given folate, vitamin B12 and B6 as supplements for 6 weeks. Fasting blood samples were collected, centrifuged and stored at 2 to 8 deg. C. Hcy levels were determined by IMx immunoassay. Results: Higher serum hcy levels, higher mean arterial blood pressure (MAP), pre-term deliveries and low foetal birth weights were noted in women with pregnancies complicated by pre-eclampsia and eclampsia as compared to control and those with placental abruption. Significant hcy lowering effects of folate, vitamin B12 and B6 supplementation were observed. Significant and positive correlation was found between hhcy and MAP (r = 0.001; p<0.001), albuminuria (r = 0.004; p< 0.01) and low birth weights (r= 0.05; p<0.06). Conclusion: Higher hcy levels in pregnancies complicated by pre-eclampsia and eclampsia have been noted. Data support the hypothesis that folate, vitamin B12 and B6 lower hcy levels in hyperhomocysteinaemic women. (author)
Hjorth Mads F
Full Text Available Abstract Background Women in low-income countries are generally considered to have a high physical workload which is sustained during pregnancy. Although most previous studies have been based on questionnaires a recent meta-analysis of doubly labeled water data has raised questions about the actual amount of physical activity performed. In this study we report objectively assessed levels of physical activity, cardiorespiratory fitness and muscular fitness among pregnant urban Ethiopian women, and their association with demographic characteristics and anthropometric measures. Methods Physical activity was measured for seven consecutive days in 304 women using a combined uniaxial accelerometer and heart rate sensor. Activity energy expenditure was determined using a group calibration in a branched equation model framework. Type and duration of activities were reported using a 24-hour physical activity recall and grip strength was assessed using a dynamometer. Results Median (interquartile-range, IQR activity energy expenditure was 31.1 (23.7-42.0 kJ/kg/day corresponding to a median (IQR physical activity level of 1.46 (1.39-1.58. Median (IQR time in sedentary, light, and moderate-to-vigorous intensity was 1100 (999–1175, 303 (223–374 and 40 (22–69 min/day, respectively. Mean (standard deviation sleeping heart rate was 73.6 (8.0 beats/min and grip strength was 21.6 (4.5 kg. Activity energy expenditure was 14% higher for every 10 cm2 difference in arm muscle area and 10% lower for every 10 cm2 difference in arm fat area and 10-week difference in gestational age. Conclusion The level and intensity of physical activity among pregnant women from urban Ethiopia is low compared to non-pregnant women from other low income countries as well as pregnant European women from high-income countries.
Ana Paula, Contiero-Toninato; Helenara Osorio, Cavalli; Ariella Andrade, Marchioro; Érika Cristina, Ferreira; Marcela Caleffi da Costa Lima, Caniatti; Regina Mitsuka, Breganó; Italmar, Navarro; Ana Lucia, Falavigna-Guilherme.
Full Text Available Introduction The aim of this study was to investigate the knowledge of toxoplasmosis among professionals and pregnant women in the public health services in Paraná, Brazil. Methods A cross-sectional observational and transversal study of 80 health professionals (44 nurses and 36 physicians) and 3 [...] 30 pregnant women [111 immunoglobulin M (IgM)- and IgG-non-reactive and 219 IgG-reactive] was conducted in 2010. An epidemiological data questionnaire was administered to the professionals and to the pregnant women, and a questionnaire about the clinical aspects and laboratory diagnosis of toxoplasmosis was administered to the professionals. Results The participants frequently provided correct responses about prophylactic measures. Regarding the clinical and laboratory aspects, the physicians provided more correct responses and discussed toxoplasmosis with the pregnant women. The professionals had difficulty interpreting the avidity test results, and the physicians stated that they referred pregnant women with high-risk pregnancies to a county reference center. Of the professionals, 53 (91.4%) reported that they instructed women during prenatal care, but only 54 (48.6%) at-risk pregnant women and 99 (45.2%) women who were not at risk reported receiving information about preventive measures. The physicians provided verbal instructions to 120 (78.4%) women, although instructional materials were available in the county. The pregnant women generally lacked knowledge about preventive measures for congenital toxoplasmosis, but the at-risk pregnant women tended to respond correctly. Conclusions This study provides data to direct public health policies regarding the importance of updating the knowledge of primary care professionals. Mechanisms should be developed to increase public knowledge because prophylactic strategies are important for preventing congenital toxoplasmosis.
Full Text Available Hypertensive disorders in pregnancy remain important problem of modern obstetrics, their frequency being 2-8% with no tendency of decreasing. To identify pregnant women with high risk and to conduct preventive treatment is very important for the practitioner. The aim of the study was to develop and justify differential management of pregnants depending on the risk of preeclampsia. 131 pregnant women in I trimester were tested to determine the risk of hypertensive disorders. Prediction model allows to identify pregnant women with risk of hypertensive disorders according to the results of testing thrombophilia genes (presence of 455G ? A polymorphism in the gene for fibrinogen ? and 4G/5G in gene of plasminogen activator inhibitor - type 1, the level of antibodies to ?2 glycoprotein-1, the level of D-dimer and the value of atherogenicity coefficient. Pregnant women with high risk of hypertensive disorders, received prophylactic treatment complex. This complex included antiplatelet therapy, correction of hyperho¬mo¬cysteinemia and hypercholesterolemia levels. Etio-pathogenic concept of prediction and prevention of pre-eclampsia associated with thrombophilia was proposed. The proposed scheme of preventive treatment allowed to normalize blood clotting parameters, lipid metabolism, to reduce the number of thrombophilia markers. The necessity of early and long-term administration of prophylactic complex was proved. This management prevents endothelial damage and deve¬lopment of pathological range of pre-eclampsia. The results of prophylactic treatment were the reduction of preeclampsia cases by 6,5 times (p < 0.05, number of complicated deliveries by 3 times (p <0.05, number of preterm birth by 6,57 times (p <0.05, cases of growth retardation by 9,8 times (p = 0.003, increase of newborns’ weight by 1,24 times (p = 0.02.
Lukasse, Mirjam; Schroll, Anne-Mette
OBJECTIVES: The primary objective was to investigate the prevalence of a history of abuse among women attending routine antenatal care in six northern European countries. Second, we explored current suffering from reported abuse. DESIGN: A prospective cohort study. SETTING: Routine antenatal care in Belgium, Iceland, Denmark, Estonia, Norway, and Sweden between March 2008 and August 2010. POPULATION: A total of 7174 pregnant women. METHODS: A questionnaire including a validated instrument measuring emotional, physical and sexual abuse. MAIN OUTCOME MEASURE: Proportion of women reporting emotional, physical and sexual abuse. Severe current suffering defined as a Visual Analogue Scale score of ?6. RESULTS: An overall lifetime prevalence of any abuse was reported by 34.8% of the pregnant women. The ranges across the six countries of lifetime prevalence were 9.7-30.8% for physical abuse, 16.2-27.7% for emotional abuse, and 8.3-21.1% for sexual abuse. Few women reported current sexual abuse, 0.4% compared with 2.2% current physical abuse and 2.7% current emotional abuse. Current severe suffering was reported by 6.8% of the women who reported physical abuse, 9.8% of those who reported sexual abuse and 13.5% for emotional abuse. CONCLUSION: A high proportion of pregnant women attending routine antenatal care report a history of abuse. About one in ten of them experiences severe current suffering from the reported abuse. In particular, these women might benefit from being identified in the antenatal care setting and being offered specialized care.
Sheth, Sangini S; Coleman, Jenell; Cannon, Tirza; Milio, Lorraine; Keller, Jean; Anderson, Jean; Argani, Cynthia
Women with perinatally acquired HIV (PAH) face unique psychosocial challenges due to the presence of a lifelong chronic illness and often unstable living situations. With advances in HIV treatment, an increasing number of those with PAH are reaching childbearing age and becoming pregnant. Depression may be an important and common factor that complicates both treatment and pregnancy outcomes in this group. We conducted a retrospective cohort study in pregnant patients with PAH to determine if history of depression is associated with nonadherence to antiretroviral therapy (ART). We reviewed charts of women with PAH receiving prenatal care at a single institution from March 1995 to December 2012. ART nonadherence was measured by patient self-report of any missed doses in the third trimester. Demographic, obstetric, and HIV infection characteristics of patients with a history of depression (dPAH) were compared to patients without a history of depression. Nine pregnancies among 6 dPAH women and 14 pregnancies among 12 PAH women without a history of depression were identified. None of the dPAH women reported 100% adherence to ART in the third trimester while 57% of women without a history of depression reported strict adherence (p = 0.04). The mean HIV RNA level at delivery was higher among dPAH women (17,399 vs. 2966 copies/Ml; p = 0.03) and fewer reached an undetectable HIV RNA level (medication adherence and treatment outcomes among pregnant women with PAH. Focused attention on diagnosis and treatment of depression in the preconception period may lead to more optimal medication adherence. PMID:25616659
Okonko, I. O.; Ijandipe, L. A.; Ilusanya, A. O.; Donbraye-Emmanuel, O. B.; Ejembi, J.; Udeze, A. O.; Egun, O. C.; Fowotade, A.; A.O. Nkang
This study reports the detection of urinary tract infections among 80 pregnant women in Oluyoro Catholic Hospital Ibadan, South-Western, Nigeria for a period of 6 months. It was carried out to detect the presence of urinary tract infection in pregnant women, and to isolate and to identify the pathogens responsible for the infection. A total of 80 clean voided mid-stream urine samples were collected from pregnant women between the ages of 21-40 years. The results showed 38 bacterial isolates w...
The aim of the study is to explore the dietary intakes of a prominent ethnic minority group of women from Sub-Saharan Africa during pregnancy, in order to identify nutritional issues of concern which may impact on pregnancy outcomes and whether different food based dietary guidelines may be required to meet their needs.
Brooten, Dorothy; Youngblut, Joanne M; Hannan, Jean; Guido-Sanz, Frank; Neff, Donna Felber; Deoisres, Wannee
The purpose of this study was to compare health problems and advanced practice nursing (APN) interventions in two types of APN care provided to 41 childbearing women with diabetes. The study's design involved content analysis of interaction logs containing the process of APN care during two clinical trials: 1) APN care was added to physician care (n = 22); and, 2) half of physician care was substituted with APN care (n = 19). Women's' health problems and APN interventions were classified using the Omaha System's Problem Scheme and Intervention Scheme. The women, in the study, had a mean age of 30, and were predominantly Black, high school graduates, with a low income. The findings identified 61,004 health problems and 60,980 APN interventions from the interaction logs. APNs provided significantly more interventions antenatally to the women in the substitution group than to those in the additive group. However, the overall categories of problems were the same in both groups. Surveillance and health teaching/counseling were the top APN interventions antenatally and postpartum. Case management interventions were third most common for both groups, while treatments and procedures constituted the least number of APN interventions in each group before and after birth. When APNs shared care more equally with physicians, they intervened differently in type and number of interventions. Their broad range of skills and depth of understanding in clinical practice, health systems, family and personal issues allowed them to intervene early and effectively. PMID:24660041
Lindsay, K L
The aim of the study is to explore the dietary intakes of a prominent ethnic minority group of women from Sub-Saharan Africa during pregnancy, in order to identify nutritional issues of concern which may impact on pregnancy outcomes and whether different food based dietary guidelines may be required to meet their needs.
Chang, Mei-Wei; Nitzke, Susan; Buist, Diana; Cain, Deborah; Horning, Stefanie; Eghtedary, Kobra
This study was conducted to identify factors that influenced stress, healthy eating and physical activity among low-income overweight or obese pregnant women. We conducted seven focus groups with 96 low-income overweight and obese pregnant women. Common themes were identified from audio tapes and transcripts. Women said that poor communication affected their relationships with spouses or significant others. They were frustrated or upset with significant others for three key reasons: failure to understand or listen to the pregnant women's pregnancy concerns, refusal to be helpful when asked and being overly concerned with the woman's safety. Most women said that they were emotional and took naps throughout the day after becoming pregnant. Many withdrew from their social interactions. They also faced numerous challenges that made healthy eating more difficult, e.g., craving for unhealthy foods and eating foods for comfort. To eat healthier, some reminded themselves to avoid overeating or stop eating in the car. Women were not physically active because of tiredness, lack of motivation, inadequate social support, or bad weather. Some stayed physically active to prevent excessive pregnancy weight gain and have an easier labor. Women equivocally said weighing themselves to manage weight would add to their stress and make them feel more depressed. When designing interventions to help low-income overweight and obese pregnant women avoid excessive pregnancy weight gain, it is important to include information and practical advice on stress management, emphasizing effective communication skills with significant others and helping them plan effective ways to manage negative feelings. PMID:25115522
Full Text Available Abstract Background In India, malaria is not uniformly distributed. Chhattisgarh is a highly malarious state where both Plasmodium falciparum and Plasmodium vivax are prevalent with a preponderance of P. falciparum. Malaria in pregnancy (MIP, especially when caused by P. falciparum, poses substantial risk to the mother and foetus by increasing the risk of foetal death, prematurity, low birth weight (LBW, and maternal anaemia. These risks vary between areas with stable and unstable transmission. The specific objectives of this study were to determine the prevalence of malaria, its association with maternal and birth outcomes, and use of anti-malarial preventive measures for development of evidence based interventions to reduce the burden of MIP. Methods A cross-sectional study of pregnant women presenting to antenatal clinics (ANC or delivery units (DU, or hospitalized for non-obstetric illness was conducted over 12?months in high (Bastar and low (Rajnandgaon transmission districts in Chhattisgarh state. Intensity of transmission was defined on the basis of slide positivity rates with a high proportion due to P. falciparum. In each district, a rural and an urban health facility was selected. Results Prevalence of peripheral parasitaemia was low: 1.3% (35/2696 among women at ANCs and 1.9% at DUs (19/1025. Peripheral parasitaemia was significantly more common in Bastar (2.8% than in Rajnandgaon (0.1% (p? Conclusions Given the overall low prevalence of malaria, a strategy of enhanced anti-vector measures coupled with intermittent screening and targeted treatment during pregnancy should be considered for preventing malaria-associated morbidity in central India.
Full Text Available Introduction: Domestic violence is one of the most important public health priorities that directly or indirectly impact on pregnancy outcomes. Given the importance of sexuality in pregnancy and its effect on marital relations, this study aimed to investigate the relationship between sexual satisfaction and violence against pregnant women.Methods: In this cross-sectional study, 430 pregnant women admitted to Fatemiyeh hospital in Shahroud during the first quarter of 2015, after obtaining informed consent, were selected to complete Larson Sexual Satisfaction Scale and ENRICH Marital Satisfaction Scale as well as Domestic Violence questionnaire. Relationships between variables were analyzed using structural equation modeling.Results: The mean age of mothers was 28±5.2 years. Prevalence of domestic violence was reported 84.4% in this study. The 81.2% of participants reported physical violence, 55.8% reported emotional violence and 25.3% reported sexual violence. The mean score of marital satisfaction in women with domestic violence (162.5 ± 28.9 was significantly lower than that in pregnant women without domestic violence (188.7 ± 31.4. A significant negative relationship was observed between sexual satisfaction and marital satisfaction with the domestic violence, --0.42 and ?–0.61, respectively.Conclusion: Considering the high prevalence of domestic violence and its significant relationship with marital satisfaction and sexual satisfaction in this study, interventions and counseling are recommended to increase marital satisfaction and sexual satisfaction and to reduce domestic violence during pregnancy.
Kim, Hye Kyung; Niederdeppe, Jeff; Graham, Meredith; Olson, Christine; Gay, Geri
Physical and psychological changes that occur during pregnancy present a unique challenge for women's physical activity. Using a theory-based prospective design, this study examines the effects of pregnant women's (a) physical activity cognitions (self-efficacy, outcome expectancy, and safety beliefs) and (b) online self-regulation activities (goal-setting and self-monitoring) on subsequent changes in their physical activity intentions and behavior during pregnancy and immediately postpartum. The authors used data from three panel surveys administered to pregnant women enrolled in a web-based intervention to promote healthy pregnancy and postpartum weight, as well as log data on their use of self-regulatory features on the intervention website. Perceived self-efficacy and perceived safety of physical activity in pregnancy enhanced subsequent intentions to be physically active. Repeated goal-setting and monitoring of those goals helped to maintain positive intentions during pregnancy, but only repeated self-monitoring transferred positive intentions into actual behavior. Theoretically, this study offers a better understanding of the roles of self-regulation activities in the processes of goal-striving. The authors also discuss practical implications for encouraging physical activity among pregnant and early postpartum women. PMID:26132887
Full Text Available AIM: To evaluate the effect of hormonal status on aerobic conjunctival flora in women.METHODS: One hundred fifty-eight women [reproductive-aged (n=55, pregnant (n=51, and postmenopausal (n=52] who admitted to outpatient clinic of Obstetrics and Gynecology Department of Denizli State Hospital were enrolled. Age, body-mass index (BMI, obstetric history, cigarette smoking, drug usage, presence of systemic disease, and intraocular pressure (IOP were recorded for each patient. The samples were taken from the lower fornix with two culture swabs and directly incubated in culture containing 5% sheep blood, eosin-methylene blue and chocolate agar. The other swab specimen was Gram stained. All growths and microscopic results were analyzed.RESULTS: The coagulase-negative Staphylococcus was the predominant organism isolated in the conjunctival samples in both three groups. The aerobic microorganism growth rate for all isolated aerobic organisms revealed no significant change in the three groups (P >0.05. The conjunctival culture positivity rates were similar in the three groups (49% in reproductive-aged, 57% in pregnant and 58% in postmenopausal women (P >0.05. Age, IOP, BMI, gravidity, parity, cigarette smoking, drug usage, and presence of systemic diseases did not have an effect on culture positivity in three groups.CONCLUSION: Results of this study showed that conjunctival aerobic flora and bacterial colonization did not differ between reproductive-aged, pregnant and postmenopausal women.
The causes of false digoxin concentrations measured in pregnant women by RIA were gone into; 103 sera of healthy women in their last trimester of pregnancy were analyzed by 4 different RIA methods. In 6 cases, falsepositive digoxin levels above 1.0 ng/ml were found; 4 of the measured digoxin levels were above 2.0 ng/ml, i.e. a clinically toxic concentration. No pseudodigoxin was detected post partum; however, the author was only able to make control measurements of 2 of the 3 positive sera between the 6th and 12th week post partum. The causes of this phenomenon remain unclear. It cannot be excluded that these pregnant women may have a still unknown hormone metabolite, resulting from a possible enzymatic defect, which cross-reacts with the digoxin antiserum and thus causes false-positive results. In those rare cases where pregnant women receive digitalis treatment, digoxin serum measurements by RIA must be analyzed very critically due to the possibility of false-positive results. (orig.)
Full Text Available Moslem pregnant women are inclined to fast during the month of Ramadan. Ketonuria and hypoglycemia are harmful in pregnancy. The aim of this study was to find out whether clinical symptoms and/ or calorie deficiency of fasting pregnant women before Eftar (ending of the daily fast can accurately predict ketonuria and hypoglycemia. In a descriptive study, 185 volunteer fasting pregnant women in Ramadan of 1999 were tested just before Eftar taking into account their clinical symptoms, intake of the previous 24 hours and testing their ketonuria and serum glucose. The positive predictive values of clinical symptoms before breaking the fast for ketonuria and hypoglycemia were 32% and 56%, respectively. The negative predictive values of clinical symptoms for ketonuria and hypoglycemia were 70% and 33%. The positive predictive values of over 500 Kcal deficiency in ketonuria and hypoglycemia were 33% and 57%. Severe calorie deficiency (more than 2000 Kcal positively predicts ketonuria in 70% of cases and sufficient calorie intake (less than 500 Kcal deficiency negatively predicts ketonuria in 93% of women. Clinical symptoms and calorie intake were not appropriate criteria for predicting ketonuria and hypoglycemia except in asymptomatic or severely calorie deficient cases or those with sufficient calorie intake whose ketonuria was predicted accurately.
Full Text Available Background & objective: Although delivering with Cesarean method is preferred in limited cases which has dangerous effects on child or mother's health, rate of cesarean is increasing vastly nowadays. The main purpose of this study was to explore Social, Cultural and Demographic factors related to this phenomenon among pregnant women of Shiraz. Materials & Methods: In this study 600 pregnant women residing in Shiraz were selected using Lin cross size of sample (multistage sampling. Data were collected through the validated questionnaire and analyzed with SPSS software by multi-variables logistic regression and X2 techniques. Results: Research hypotheses about significant relation among these factors (age, age of marriage, education, spouse’s education, occupational status, place of birth, social class status, previous childbirth method, record of barrenness, place of previous childbirth, place of pregnant care, record of cesarean in family and attitude toward cesarean with choice of cesarean have been approved. Research hypotheses about month of pregnancy, number of pregnancy and knowledge of delivery method and cesarean have been rejected. Conclusion: Due to significant positive attitude of women's towards the cesarean, rather than normal delivery, it is necessary to inform them about the advantages of normal delivery and health hazard which might cause by Cesarean to the mother and child. The change of women's attitude about cesarean is needed to avoid further complication.
Full Text Available Dreams are thought to respond to self- and socially-relevant situations that evoke strong emotions and require rapid adaptation. First pregnancy is such a situation during which maternal mental representations (MMR of the unborn baby, the self and significant others undergo remodelling. Some studies suggest that dreams during pregnancy contain more MMR and are more dysphoric, but such studies contain important methodological flaws. We assessed whether dreamed MMR, like waking MMR, change from 7 months to birth, and whether pregnancy–related themes and non-pregnancy characteristics are also transformed. Sixty non-pregnant and 59 pregnant women (37 early and 22 late 3rd trimester completed demographic and psychological questionnaires and 14-day home dream logs. Dream reports were blindly rated and later analyzed following four dream categories: 1 Dreamed MMR, 2 Quality of baby/child representations, 3 Pregnancy-related themes, 4 Non-pregnancy characteristics. Controlling for age, relationship and employment status, education level and state anxiety, pregnant groups reported more dreams depicting themselves as a mother or with babies/children than did non-pregnant women (all p?0.006. Baby/child representations were less specific in late 3rd than in early 3rd trimester (p=0.005 and than in non-pregnant women (p=0.01. Pregnant groups also had more pregnancy, childbirth and fetus themes (all p?.01. Childbirth content was higher in late than in early 3rd trimester (p=0.01. Pregnant groups had more morbid elements than did the non-pregnant group (all p<.05. Dreaming during pregnancy appears to reflect daytime processes of remodelling MMR of the woman as a mother and of the unborn baby, and parallels a decline in the quality of baby/child representations in the last stage of pregnancy. More frequent morbid content in late pregnancy suggests that the psychological challenges of pregnancy are reflected in a generally more dysphoric emotional tone in dream content.
Tevdorashvili, G; Tevdorashvili, D; Andghuladze, M; Tevdorashvili, M
Group B streptococcus (GBS; Streptococcus agalactiae) are encapsulated gram-positive cocci belonging to Lancefield group B, that frequently colonizes the human genital and gastrointestinal tracts. It is an important cause of illness in three categories of population: infants, pregnant women, and adults with underlying medical conditions. In pregnant women and postpartum women, GBS is a frequent cause of asymptomatic bacteriuria, urinary tract infection, upper genital tract infection (i.e. intraamniotic infection or chorioamnionitis), postpartum endometritis (8%), pneumonia (2%), puerperal sepsis (2%), and bacteremia without a focal site (31%). It also can cause focal infections such as pneumonia, meningitis, and endocarditis, albeit rarely. Invasive maternal infection with GBS is associated with pregnancy loss and preterm delivery. Prior to the widespread use of maternal intrapartum chemoprophylaxis, maternal colonization with GBS conferred an increased risk of chorioamnionitis, and early postpartum infection. The serotype distribution of invasive GBS infection in pregnant women is similar to that of early-onset neonatal disease. The most common GBS serotypes causing invasive disease in adults and neonates are Ia, Ib, III, and V. Vaccination of adolescent women is considered an ideal solution. However, recent reports (April 2015) have shown that serotype IV GBS is emerging in pregnant carriers and causing infections in neonates and adults. This emergence is of concern because GBS conjugate vaccines that are being developed to prevent invasive disease may protect only against serotypes Ia, Ib, II, III, and V, or combinations thereof. Though research for the development of such a vaccine is underway, a good candidate vaccine has yet to surface. PMID:25953932
Full Text Available Fidelis Agwu Onu,1 Leonard Ogbonna Ajah,1 Paul Olisaemeka Ezeonu,1 Odidika Ugochukwu Joannes Umeora,1 Perpetus Chudi Ibekwe,1 Monique Iheoma Ajah2 1Department of Obstetrics and Gynaecology, Federal Teaching Hospital, 2Department of Microbiology, Ebonyi State University, Abakaliki, Nigeria Background: Detecting and treating asymptomatic bacteriuria (ASB prevents urinary tract infection and its consequences. The cost-effectiveness of routine screening for ASB in pregnancy is controversial. In populations with high prevalence, however, it is worthwhile and justifiable. Aim: To determine the profile, prevalence, microbiological isolates, and risk factors of ASB among booking antenatal clinic attendees in Abakaliki, Nigeria. Materials and methods: This was a cross-sectional study involving booking antenatal clinic attendees at the Federal Teaching Hospital, Abakaliki, who met the inclusion criteria. This study occurred between January and December, 2012. The midstream urine samples of these women were subjected to microscopy, culture, and sensitivity. Results: A total of 300 randomly selected booking antenatal clinic attendees participated in the study; 74 of them had ASB, giving a prevalence of 24.7%. With the exception of rural residence, sociodemographic and obstetric characteristics did not influence the risk of ASB among the participants in this study. Staphylococcus aureus was the commonest organism isolated. The majority of the organisms were sensitive to ofloxacin and ceftriaxone. Conclusion: There is a high prevalence of ASB among pregnant women in Abakaliki. With the exception of rural dwelling, sociodemographic and obstetric characteristics did not significantly influence the risk of ASB among these pregnant women. Therefore, routine ASB screening of pregnant women is recommended in our environment. Keywords: asymptomatic bacteriuria, pregnant women, Abakaliki
Full Text Available Introduction: Tenofovir is a commonly used component of antiretroviral therapy (ART to reduce vertical transmission of HIV. Although systematic review of tenofovir use in pregnancy concluded it to be low risk for foetal abnormalities (1, data is limited on its impact on renal function in pregnant women. A recent South African study (2 concluded that renal dysfunction in HIV-infected pregnant women is significantly less common than in other HIV-infected adults, however there is currently no UK data. We aimed to investigate the effect of tenofovir on renal function in HIV-1 positive pregnant women in a UK clinic. Methods: We retrospectively analyzed data on renal function in pregnancy from a cohort of women attending a busy inner city London antenatal clinic. All women were screened for renal function throughout pregnancy via serum creatinine and estimated glomerular filtration rate (eGFR calculated using modification of diet in renal disease (MDRD and corrected for ethnicity. Results: Ninety-seven HIV-1 positive women were registered at Homerton Hospital antenatal service of a total of 105 pregnancies between January 2010 and September 2013. Tenofovir was prescribed in 71/105 pregnancies (67.6%. Of the 71 pregnancies, 41 were prescribed tenofovir pre-conception (57.7%. Of the pregnant women who started tenofovir in pregnancy, 21/31 (67.7% were initiated before week 24 of pregnancy, in line with British HIV association (BHIVA guidelines (3. There was no deterioration in median serum creatinine or decline in eGFR in women prescribed tenofovir during pregnancy. At six weeks after delivery, in the 42 women who continued tenofovir therapy and had eGFR measured, one woman had eGFR=60, all others eGFR >90 (Table 1. Conclusions: Consistent with current guidelines and experience, this study shows tenofovir did not cause decline in renal function in pregnancy in our cohort of HIV-1 positive women, whether started during pre-conception or during pregnancy. More evidence should be prospectively collected looking at effects of tenofovir on other measures of tubular renal function in pregnancy such as proteinuria and protein-creatinine ratio.
The Treatment of Obese Pregnant Women (TOP) study : a randomized controlled trial of the effect of physical activity intervention assessed by pedometer with or without dietary intervention in obese pregnant women
Renault, Kristina M; NØrgaard, Kirsten
The objective of the study was to assess physical activity intervention assessed by a pedometer with or without dietary intervention on gestational weight gain (GWG) in obese pregnant women by comparing with a control group.
Ferszt, Ginette G; Erickson-Owens, Debra A
It is estimated that 6-10% of women are pregnant when they enter the prison system. The majority have had little, if any, prenatal care and/or childbirth education. Given economic constraints, the educational and support needs of this population are often not met. In response to these needs, an educational/support group was developed and led by a social worker, a mental health clinical nurse specialist, and a nurse midwife in a women's correctional facility in the Northeast. Women in various stages of pregnancy and early postpartum voluntarily attended. The need for education and psychosocial support was overwhelming. This group fostered a safe space for women to discuss real-life issues in a supportive environment. Meeting the educational and support needs of incarcerated women is paramount. PMID:18522603
Mbizvo Elizabeth M
Full Text Available Abstract Objectives To determine the prevalence of sexually transmitted infections (STIs and other reproductive tract infections (RTIs among pregnant women in Moshi, Tanzania and to compare the occurrence of STIs/RTIs among human immunodeficiency virus (HIV-infected and uninfected women. Methods Pregnant women in their 3rd trimester (N = 2654 were recruited from two primary health care clinics between June 2002 and March 2004. They were interviewed, examined and genital and blood samples were collected for diagnosis of STIs/RTIs and HIV. Results The prevalence of HIV, active syphilis and herpes simplex virus – type 2 (HSV-2 were 6.9%, 0.9% and 33.6%, respectively, while 0.5% were positive for N gonorrhoeae, 5.0% for T vaginalis and 20.9% for bacterial vaginosis. Genital tract infections were more prevalent in HIV-seropositive than seronegative women, statistically significant for syphilis (3.3% vs 0.7%, HSV-2 (43.2% vs 32.0%, genital ulcers (4.4% vs 1.4% and bacterial vaginosis (37.2% vs 19.6%. In comparison with published data, a declining trend for curable STIs/RTIs (syphilis, trichomoniasis and bacterial vaginosis was noted. Conclusion Rates of STIs and RTIs are still high among pregnant women in Moshi. Where resources allow, routine screening and treatment of STIs/RTIs in the antenatal care setting should be offered. Higher STIs/RTIs in HIV-seropositive women supports the expansion of HIV-counseling and testing services to all centers offering antenatal care. After identification, STIs/RTIs need to be aggressively addressed in HIV-seropositive women, both at antenatal and antiretroviral therapy care clinics.
Angelica E., Miranda; Valdir M., Pinto; Charlotte A., Gaydos.
Full Text Available Our goal was to determine the prevalence of Trichomonas vaginalis and its associated risk factors in parturient women aged 15–24 years attending Brazilian public maternity units. Participants answered a demographic, behavioral, and clinical data questionnaire. A sample of urine was screened for T. v [...] aginalis. A total 299 women participated in this study. The prevalence rate of T. vaginalis was 7.7% (95% CI: 4.7–10.7%). The factors associated with T. vaginalis were use of illicit drugs OR = 4.70 (95% CI: 1.63–13.56, p = 0.004)] and not attending antenatal care OR = 5.15 (95% CI: 1.15–23.25, p = 0.032)]. These data demonstrate that it is important to discuss how to include routine screening for T. vaginalis during antenatal care in Brazil.
Sabers, Anne; Petrenaite, Vaiva
Previous studies have demonstrated that the pharmacokinetics of the new antiepileptic drug (AED) lamotrigine (LTG) are substantially influenced by pregnancy and are more likely to be associated with seizure deterioration in pregnancy compared to other AEDs. This is of great concern, as LTG has developed into a first-line AED for women of childbearing age. In this study we evaluated the risk of seizure deterioration in a cohort of women treated with LTG monotherapy (n = 42) who were closely monitored with frequent dose adjustments based on monthly routine plasma level determinations. It was demonstrated that with this close monitoring set-up, the risk of increased seizure frequency (19%) was not higher than that reported for other AED treatment regimens.
Carlsen, Emma M; Renault, Kristina M; Nørgaard, Kirsten; Nilas, Lisbeth; Jensen, Jens-Erik B; Hitz, Mette F; Michaelsen, Kim F; Cortes, Dina; Pryds, Ole
INTRODUCTION: Offspring of obese women have both short- and long-term increased morbidities. We investigated the relationship between maternal 2-h plasma glucose level determined by oral glucose tolerance test, degree of obesity, gestational weight gain and total fat, abdominal fat, and fat-free masses in the offspring of obese mothers. MATERIAL AND METHODS: Obese mother-newborn dyads were recruited and 2-h plasma glucose levels were assessed during gestational weeks 27-30; neonatal body composi...
Law, Graham R; Ellison, George T H; Secher, Anna L; Damm, Peter; Mathiesen, Elisabeth R; Temple, Rosemary; Murphy, Helen R; Scott, Eleanor M
OBJECTIVE: Continuous glucose monitoring (CGM) is increasingly used to assess glucose control in diabetes. The objective was to examine how analysis of glucose data might improve our understanding of the role temporal glucose variation has on large-for-gestational-age (LGA) infants born to women with diabetes. RESEARCH DESIGN AND METHODS: Functional data analysis (FDA) was applied to 1.68 million glucose measurements from 759 measurement episodes, obtained from two previously published randomize...
The introduction of new models of care in the Irish maternity services has been recommended by both advocacy groups and strategic reports. Yet there is a dearth of information about what models of care pregnant women want. We surveyed women in early pregnancy who were attending a large Dublin maternity hospital. Demographic and clinical details were recorded from the hospital chart. Of the 501 women, 351 (70%) (352 (70.3%) of women wanted shared antenatal care between their family doctor and either a hospital doctor or midwife. 228 (45.5%) preferred to have their baby delivered in a doctor-led unit, while 215 (42.9%) preferred a midwifery-led unit. Of those 215 (42.9%), 118 (55%) met criteria for suitability. There was minimal demand (1.6%) for home births. Choice was influenced by whether the woman was attending for private care or not. Safety is the most important factor for women when choosing the type of maternity care they want. Pregnant women want a wide range of choices when it comes to models of maternity care. Their choice is strongly influenced by safety considerations, and will be determined in part by risk assessment.
Jacobson, Lisette T; Dong, Frank; Scheuermann, Taneisha S; Redmond, Michelle L; Collins, Tracie C
Smoking during pregnancy is associated with poor birth outcomes. The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) is a public nutritional assistance program for low-income pregnant women and their children up to age five. This study examined differences in smoking behavior among women enrolled in the Kansas WIC program. A secondary analysis was conducted using the Pregnancy Nutrition Surveillance System dataset of enrolled women between 2005 and 2011. Geographic residency status was obtained through application of the Census tract-based rural-urban commuting area codes. Chi square tests of association were used to assess differences. Multi-variable binary logistic regression was used to assess maternal characteristics and smoking 3 months prior to pregnancy. Total sample size averaged 21,650 women for years 2005 through 2011. Low-income, rural pregnant women smoked at significantly higher rates before, during, and after pregnancy. High smoking rates have remained unchanged since 2008. The following characteristics were associated with reduced odds of smoking 3 months prior to pregnancy: being 17 years old or younger, Hispanic, a high school graduate, urban location, normal body mass index, no live births prior to current pregnancy, and using multi-vitamins. Results from this study indicate that the WIC population in rural areas may have different needs regarding smoking cessation programming than the urban WIC population. Findings help inform WIC program administrators and assist in enhancing current smoking cessation services to the Kansas WIC population. PMID:25925718
Background Pregnant women living in an area of stable malaria transmission such as Lagos, Nigeria, have been identified as being at an increased risk of the effects of malaria infection. In this area, most of the infections are asymptomatic which means they are overlooked and untreated much to the detriment of the mother and her foetus. The reality of scaled-up malaria interventions with long-lasting insecticide treated nets, vector control, artemisinin combination therapy (ACT) and intermittent preventive treatment of malaria pregnancy (IPTp) using sulphadoxine pyrimethamine (SP) is that it is also essential to determine the risk factors at play in these kinds of circumstances. This study was aimed at identifying the factors associated with risk of malaria infection in pregnant women in Lagos, Southwest Nigeria. Methods Demographic information and malaria prevention practices of the pregnant women studied were captured using structured questionnaire. Microscopy was used to establish malaria infection, species identification and parasite density. Relative risk and multivariate logistic regression analysis were used to compare factors associated with malaria in pregnant women. Results Malaria microscopy details, demographic information and malaria prevention practices of the pregnant women were obtained using a structured questionnaire. The prevalence of malaria using peripheral blood from 1,084 pregnant women that participated in the study was 7.7%. Plasmodium falciparum (P. falciparum) was seen in 95.2% of the cases as either mixed infection with P. malariae (3.6%) or as a mono infection (91.6%). Malaria preventive practices associated with a significant reduction (P<0.05) in the malaria infection was the use of insecticide sprays (RR = 0.36, 95 C.I. 0.24-0.54), and the combined use of insecticide spray and insecticide-treated nets (ITN) (RR= 6.53, 95% C.I. 0.92-46.33). Sleeping under ITN alone (RR = 1.07, 95% C.I. 0.55-2.09) was not associated with significant reduction in malaria infection among the study participants with malaria parasitaemia. Young maternal age (<20years) (RR = 2.86, 95% C.I. 1.48 – 5.50), but not primigravidity (RR = 1.36, 95% C.I. 0.90-2.05), was associated with an increased risk of malaria infection during pregnancy. After a multivariate logistic regression, young maternal age (OR = 2.61, 95% C.I. 1.13 – 6.03) and the use of insecticide spray (OR = 0.38, 95% C.I. 0.24-0.63) were associated with an increase and a reduction in malaria infection, respectively. Conclusion Malaria prevalence was low among the pregnant women studied. Young maternal age and non-usage of insecticidal spray were the main factors associated with an increased risk of malaria infection among pregnant women in Lagos, Nigeria. PMID:24001135
Andersen, Stine Linding
Iodine is required for the synthesis of thyroid hormones, which are crucial regulators of early brain development. The source of iodine in the fetus and the breastfed infant is maternal iodine, and adequate iodine intake in pregnant and breastfeeding is of major concern. Severe iodine deficiency can cause irreversible brain damage, whereas the consequences of mild to moderate iodine deficiency are less clear. Denmark was previously iodine deficient with regional differences and a mandatory iodine fortification of salt was introduced in the year 2000. The PhD thesis investigated intake of iodine supplements and urinary iodine status in Danish pregnant and breastfeeding women after introduction of iodine fortification in a region of Denmark with previously moderate iodine deficiency. Additionally, thesis addressed mechanisms of iodiden transport to the fetus across the placenta and methodological challenges in the evaluation of urinary iodine status in prengnant and breastfeeding women.
Petmy Lohoue J
Full Text Available Pregnant women may contaminate new borns and babies with vaginal candidiasis and ringworms, thus the choice of this group for our study. Cases were recruited at the UHC Yaounde from June 2001 to September 2002. Four hundred and thirty (29.3% out of 1467 examined presented at least one mycosis. The principal lesions were vaginal thrush 44% and athleteâ€?s foot 22%. The causal fungi were essentially yeasts with the predominance of candida albicans (72% and for the dermatophytes, Trichophyton rubrum (71.84%. The other species were Candida tropicalis, Candida Krusei, Candida parapsilosis, candida glabrata, Malassezia furfur, Trichosporon sp., Trichophyton soundanense, Trichophyton interdigitale, Thrichophyton mentagrophytes and scytalidium dimidiatum. Because these infections affect up to 30% of pregnant women, they should be taken into consideration during prenatal care.
Jackson, Afton; Shannon, Lisa
The purpose of this study was to assess factors associated with chronicity of intimate partner violence (IPV) among pregnant substance abusers. A total of 114 pregnant women entering an inpatient, detoxification unit voluntarily agreed to participate in a study about women's health and well-being. Face-to-face interviews were used for data collection. A multiple linear regression assessed the relationship between background characteristics, substance use, and IPV chronicity. Protective factors, which were associated with reduced chronicity of IPV, included whether most recent/current intimate partner fathered pregnancy, whether the mother was currently in a relationship with most recent/current intimate partner, whether the mother received greater social support, and increasing age. Childhood sexual abuse was associated with increased chronicity of IPV. Results suggest important prevention, intervention, and treatment implications for this vulnerable population. PMID:26086380
Ana Claudia Molina Cavassini
Full Text Available OBJECTIVE: To compare inpatient and outpatient care costs for pregnant/parturient women with diabetes and mild hyperglycemia. METHODS: A prospective observational quantitative study was conducted in the Perinatal Diabetes Center in the city of Botucatu, Southeastern Brazil, between 2007 and 2008. Direct and indirect costs and disease-specific costs (medications and tests were estimated. Thirty diet-treated pregnant women with diabetes were followed up on an outpatient basis, and 20 who required insulin therapy were hospitalized. RESULTS: The cost of diabetes disease (prenatal and delivery care was US$ 3,311.84 for inpatients and US$ 1,366.04 for outpatients. CONCLUSIONS: Direct and indirect costs as well as total prenatal care cost were higher for diabetic inpatients while delivery care costs and delivery-postpartum hospitalization were similar. Prenatal and delivery-postpartum care costs were higher for these patients compared to those paid by Brazilian National Health System.
V N Petrova
Full Text Available The aim is to study a condition of thyroid and fetoplacental systems at pregnant women with clinically euthyroid goiter. Materials and methods: 116 pregnant women have been included in the basic group with clinically euthyroid goiter. The control group was made by 60 pregnant women with physiologically proceeding pregnancy, not having anamnestic and the clinical data on diseases of the thyroid. Inspection included: definition of concentration thyroid-stimulating hormone (TSH and free thyroxine (fT4 by a radio-immunologic method, sets “RIA-gnost” (France and the maintenance of antibodies to thyroid peroxydase (anti-TPO by a method hard phase immune-enzyme analysis; ultrasonic assessment of a thyroid with the help of device SONOACE 8800 “GAIA MT”; ultrasonic fetometry, placentography, measurement of amniotic fluid volume, doppler ultrasound examination of the blood flow, an estimation of a functional condition of a fetus on parameters of its biophysical profile (BP and cardiotocography (CTG, carried out on device “Oxford Sonicaid Team S8000”. Results: At studying hormonal function thyroid systems at 25 pregnant (21.6% with euthyroid goiter in the third trimester of pregnancy a level fT4 norms were lower and had values from 4.5 up to 6.9 ng/ml, therefore an average level fT4 at pregnant women of the basic group was authentically lower, than in control (8.26 ± 0.30 and 10.71 ± 0.52 ng/ml, accordingly. At the retrospective analysis it is established, that only at 5 of 116 (4.3% pregnant women with a goiter were not complications pregnancy, at the others — 111 (95.7% took place a combination various obstetric complications: an anemia — at 72 (62.0%, threat noncarrying of pregnancy — at 75 (64.6 %, an early toxicosis — at 45 (38.6%, a gestosis — at 47 (40.5% which frequency authentically is higher, than in control group: 20.0%, 25.0%, 16.6%. 20.0%, accordingly, ? < 0.05. Average Estimation CTG at patients of the basic group is authentically lower, than in control (7.2 ± 0.1; 7.9 ± 0.07 points accordingly, ? < 0.05. The expressed infringement of biophysical activity of a fetus in the basic group proved to be true lower average estimation BP (8.3 ± 0.12 a point, than in control group (9.8 ± 0.13 a point. With a goiter the arrest of development of an intra-uterine fetus is diagnosed for pregnant women — at 19 (16.4%, infringement placentation — at 14 (12.1%, hypamnions - at 27 (23.3%, that is authentically more often, than in control group (9.5%; 3.3%; 3.3%, accordingly, ? < 0.05. Conclusion: Thus, at pregnant women with euthyroid goiter decrease in thyroid function in second half of the pregnancy, resulting to development of hypothyroxinemia in 21,6 % of supervision is marked. Pregnancy at patients with euthyroid goiter frequently has the complicated character. At women with euthyroid goiter of change in fetoplacental system meet more often and in a significant greater measure that demands their duly revealing and correction.
...of IRBs in connection with observational research involving pregnant women...PROTECTION OF HUMAN SUBJECTS Observational Research: Additional Protections...Involved as Subjects in Observational Research Conducted or Supported...
...what settings may the Single Parents, Displaced Homemakers, and Single Pregnant Women Program...including area vocational education schools, and community-based...c), that serve single parents, displaced...C. 2335(b)) Sex Equity...
Vestgaard, Marianne; Nielsen, Lene Ringholm; Rasmussen, Åse Krogh; Damm, Peter; Mathiesen, Elisabeth R
In pregnant women with type 1 diabetes, we evaluated whether the presence of thyroid peroxidase autoantibodies (anti-TPO) was associated with changes in thyroid function, metabolic control and pregnancy outcome.
Full Text Available The article presents the results of monitoring of iodine intake and thyroid status in pregnant women in Saratov region according to the two cross-sectional studies in 1999 and 2008. The study involved 229 pregnant women. It has been established that there is a decrease in frequency of endemic goiter in pregnant women from 52,8 to 23,6% and increase in median urinary ioduria from 33,0 to 115,5 ug/l. However, iodine intake in pregnancy remains insufficient, as currently the median urinary ioduria is 150-249 ug/l (WHO, 2007. The frequency of maternal hypothyroxinemia, the most significant iodine deficiency disorders in pregnant women, has not changed in a 10-year period (1999 - 46,3%; in 2008 - 55,7%; p>0,1. The research has not obtained significant differences in the frequency of interrelated with pregnancy and delivery complications within two groups of patients
Artz, Laura A.; Kempf, Volkhard A.J.; Autenrieth, Ingo B.
Group B streptococci (GBS) are the most frequent pathogens in neonates with sepsis. A rapid screening method is required to identify carriage of GBS in pregnant women at the time of delivery. In order to detect GBS in vaginal specimens, the efficiency of the standard culture versus fluorescent in situ hybridization (FISH) was investigated. In 258 examined vaginal specimens, FISH identified 58 of the 59 GBS-positive samples (98.3%), whereas by means of standard culture only 38 specimens were p...
Gerstenbluth Isaac; Koolman-Wever Sharline; van Osch Gerard; Durand Aimée; Muskiet Fred D; Voigt Ralph; van Vught Lonneke A; Hermanides Hillegonda S; Smit Colette; Duits Ashley J
Abstract Background Effective interventions to prevent mother-to-child HIV transmission (PMTCT) exist and when properly applied reduce the risk of vertical HIV transmission. As part of optimizing PMTCT in the Dutch Caribbean we developed a set of valid and applicable indicators in order to assess the quality of care in HIV-infected (pregnant) women and their newborns. Methods A multidisciplinary expert panel of 19 experts reviewed and prioritized recommendations extracted from locally used in...
Groves, AK; Kagee, A.; Maman, S; Moodley, D.; Rouse, P
Intimate partner violence (IPV) during pregnancy has been associated with multiple negative health outcomes for the mother, including emotional distress during pregnancy. However, little is known about IPV during pregnancy and its association with emotional distress among pregnant women in South Africa. The objectives of this study were to determine the prevalence of both emotional distress and IPV during pregnancy, to identify whether different exposures of violence and relational control we...
Mehrangiz Ebrahimi-Mameghani; Esmat Mehrabi; Mahin Kamalifard; ParisaYavarikia
Background: The prevalence of obesity is increasing throughout the world. Obesity assessed by body mass index (BMI) has shown to be associated with gestational complications while the relationship using waist circumference (WC) is not clear yet. The present study was aimed to determine the relationship be-tween WC and adverse pregnancy complications.Methods: In this prospective cohort study, 1140 nulliparous pregnant women at 1st trimester of pregnancy referred to health care centers in Tabri...
Tanvig, Mette; Jensen, Dorte Møller
Worldwide, the prevalence of obesity has reached epidemic proportions. In Denmark one third of all pregnant women are overweight and 12 % are obese. Perhaps even more concerning, a dramatic rise in the prevalence of childhood overweight and obesity has also been evident over recent decades. The obesity epidemic is not simply a consequence of poor diet or sedentary lifestyles. Obesity is a multifactorial condition in which environmental, biological and genetic factors all play essential roles. Th...
Lindhardt, Christina L; Rubak, Sune Leisgaard Mørck; Hansen, Helle Puggård; Jørgensen, Jan; Mogensen, Ole
Aim: To explore how healthcare professionals experience motivational interviewing as a useful? technique when working with pregnant women with obesity. Design: A qualitative, descriptive study based on interviews with eleven healthcare professionals. Setting: Face to face interviews with obstetric healthcare professionals. Sample(size?): Eleven healthcare professionals. Methods: A qualitative descriptive method was applied to semi-structured interviews. The healthcare professional’s experiences ...
Lindhardt, Christina Louise; Rubak, Sune; Mogensen, Ole; Hansen, Helle Ploug; Goldstein, Henri; Lamont, Ronald F; Joergensen, Jan Stener
OBJECTIVE: to explore and describe how healthcare professionals in the Southern Region of Denmark experienced motivational interviewing as a communication method when working with pregnant women with obesity. DESIGN: a qualitative, descriptive study based on face-to-face interviews with 11 obstetric healthcare professionals working in a perinatal setting. METHODS: a thematic descriptive method was applied to semi-structured interviews. The healthcare professional?s experiences were recorded verb...
Jones, D. E.; Friedl, E M; Kanarek, K S; Williams, J K; Lim, D V
Pregnant women admitted to Tampa General Hospital, Tampa, Fla., were cultured for group B streptococci (GBS). Culture swabs were placed into enriched, selective Todd-Hewitt medium and were quantitated for GBS. The broth cultures were tested by slide coagglutination before incubation and after 5 and 20 h of incubation. Fifty-four (27%) of the 201 maternity patients cultured were positive for GBS and were identified as such by slide coagglutination. A strong correlation was found between the ma...
de Wit, Linda; Jelsma, Judith G M; van Poppel, Mireille N M; Bogaerts, Annick; Simmons, David; Desoye, Gernot; Corcoy, Rosa; Kautzky-Willer, Alexandra; Harreiter, Jürgen; van Assche, Andre; Devlieger, Roland; Timmerman, Dirk; Hill, David; Damm, Peter; Mathiesen, Elisabeth R; Wender-Ozegowska, Ewa; Zawiejska, Agnieszka; Rebollo, Pablo; Lapolla, Annunziata; Dalfrà, Maria G; Del Prato, Stefano; Bertolotto, Alessandra; Dunne, Fidelma; Jensen, Dorte M; Andersen, Liselotte; Snoek, Frank J
BACKGROUND: The purpose of this study was to examine the association between mental health status (i.e. depressed mood and pregnancy-related worries) and objectively measured physical activity levels in obese pregnant women from seven European countries. METHODS: Baseline data from the vitamin D and lifestyle intervention for the prevention of gestational diabetes mellitus (DALI) study were used. Time spent in moderate-to-vigorous physical activity (MVPA) and sedentary behaviour was measured wit...
Zhila Amirkhani; Meisam Akhlaghdoust; Media Abedian; Gelareh Rabie Salehi; Nesa Zarbati; Maryam Mogharehabed; Sahba Arefian; Mina Jafarabadi
Objective: To study the pregnancy outcomes in first trimester vaginal bleeding.Materials and methods: This cross sectional study was done on 60 pregnant women with first trimestervaginal bleeding referring to university hospitals affiliated to Islamic Azad University, Tehran, Iran. Allwomen were evaluated for the outcomes including abortion, preterm rapture of membranes, pretermlabor, second and third trimester vaginal bleeding, low birth weight and intra uterine growth retardationand the mod...
Lund Ole; Fievet Nadine; Gnidehou Sédami; Ermont Caroline; Andersen Pernille; Guitard Juliette; Deloron Philippe; Ndam Nicaise
Abstract Background Pregnant women acquire protective antibodies that cross-react with geographically diverse placental Plasmodium falciparum isolates, suggesting that surface molecules expressed on infected erythrocytes by pregnancy-associated malaria (PAM) parasites have conserved epitopes and, that designing a PAM vaccine may be envisaged. VAR2CSA is the main candidate for a pregnancy malaria vaccine, but vaccine development may be complicated by its sequence polymorphism. Methods The dyna...
Fowkes, FJ; MCGREADY, R; Cross, NJ; Hommel, M; SImpson, JA; Elliott, SR; Richards, JS; Lackovic, K; Viladpai-Nguen, J; Narum, D; Tsuboi, T.; Anders, RF; Nosten, F; Beeson, JG
BACKGROUND: How antimalarial antibodies are acquired and maintained during pregnancy and boosted after reinfection with Plasmodium falciparum and Plasmodium vivax is unknown. METHODS: A nested case-control study of 467 pregnant women (136 Plasmodium-infected cases and 331 uninfected control subjects) in northwestern Thailand was conducted. Antibody levels to P. falciparum and P. vivax merozoite antigens and the pregnancy-specific PfVAR2CSA antigen were determined at enrollment (median 10 week...
Nielsen, L.R.; Johansen, M.; Pedersen-Bjergaard, U.; Damm, P.; Thorsteinsson, B.; Mathiesen, E.R.
OBJECTIVE- In pregnancy with type 1 diabetes, we evaluated occurrence of mild and severe hypoglycemia and analyzed the influence of strict metabolic control, nausea, Vomiting, and other potential predictors of occurrence of severe hypoglycemia. RESEARCH DESIGN AND METHODS- A prospective observational study of 108 consecutive pregnant women with type 1 diabetes was conducted. At 8, 14, 21, 27, and 33 weeks of gestation, patients performed self-monitored plasma glucose (SMPG) (eight/day) for 3 day...
Ventura, T; Gomes, MC; Carreira, T
Background: Stress and anxiety during pregnancy have been associated with premature and low birth weight babies, presumably through fetus over exposion to glucocorticoids. Antenatal stress also seems to have long-term effects upon infant development and adult health. However, medication for stress may carry risks to the expectant mother, therefore the efficacy of nonpharmacological interventions should be investigated. Methods: Pregnant women (n = 154) awaiting amniocentesis, were ra...
A Travassos; I Nobrega; T Haguihara; Brites, C.
The risk of HIV perinatally transmition is highest in the 3rd trimester and is correlated with the imune status and especially with the maternal viral load close to delivery. The speed of the viral load decay is an importante strategy for the prevention of mother-to-child transmition (MTCT) in late-presenting pregnant women. Poor access to prenatal care and HIV late diagnosis during pregnancy remains a major problem in Bahia, Brazil. The integrase inhibitor raltegravir has significantly highe...
VELEZ, MARTHA L.; Montoya, Ivan D; JANSSON, LAUREN M.; Walters, Vickie; Svikis, Dace; Jones, Hendree E.; Chilcoat, Howard; Campbell, Jacquelyn
This study examined the prevalence of exposure to violence among drug-dependent pregnant women attending a multidisciplinary perinatal substance abuse treatment program. Participants (N = 715) completed the Violence Exposure Questionnaire within 7 days after their admission to the program. Their rates of lifetime abuse ranged from 72.7% for physical abuse to 71.3% for emotional abuse to 44.5% for sexual abuse. Their rates of abuse remained high during their current pregnancy, ranging from 40....
Raquel Guimarães Nobre
Full Text Available Objective: To investigate the eating behavior and body image perception in pregnant women attending a high-risk outpatient center. Methods: A quantitative, cross-sectional, observational study conducted with 28 overweight pregnant women attending the first consultation in the nutrition outpatient center of a maternity hospital in Fortaleza-CE, from December 2010 to February 2011. It has been used a pre-established form containing data on the characterization of the sample (socioeconomic, obstetric, and nutritional, the BES (Binge Eating Scale to assess binge eating and BSQ (Body Shape Questionnaire to assess the severity or absence of body image disorder. The variables were presented as mean ± standard deviation and simple frequency and percentage. The Pearson’s correlation was used to verify the relation between body image and binge eating, considering p <0.05. Results: The pregnant women studied had a mean age of 29.4 ± 6.3 years and mean gestational age of 24.6 ± 8.2 weeks. It was found a prevalence of 71.5% (n=20 of body image disorder and 17.8% (n=5 of binge eating. It was also observed a direct and significant correlation between the body image perception and the degree of binge eating (r=0.4358, p=0.020. Conclusion: The high rate of body image disorder positively related to a significant binge eating indicates an unfavorable adjustment of this group of pregnant women to alterations in weight and body shape and size, which are inherent to pregnancy, standing out as group that needs special attention by the professional team. doi:10.5020/18061230.2014.p256
Buckley, Jessie P; Palmieri, Rachel T.; Matuszewski, Jeanine M.; Herring, Amy H; Baird, Donna D.; HARTMANN, Katherine E.; Hoppin, Jane A.
Human phthalate exposure is ubiquitous, but little is known regarding predictors of urinary phthalate levels. To explore this, 50 pregnant women aged 18–38 years completed two questionnaires on potential phthalate exposures and provided a first morning void. Urine samples were analyzed for 12 phthalate metabolites. Associations with questionnaire items were evaluated via Wilcoxon tests and t-tests, and r-squared values were calculated in multiple linear regression models. Few measured factors...
Danielle Satie, Kassada; Sonia Silva, Marcon; Maria Angélica, Pagliarini; Robson Marcelo, Rossi.
Full Text Available OBJETIVO: Determinar a prevalência do uso de drogas de abuso por gestantes. MÉTODO: Estudo transversal que incluiu 394 gestantes usuárias de serviço de atenção primária. A variável dependente foi o uso de drogas de abuso durante a gestação e as variáveis independentes foram: socioeconômicas e obstét [...] ricas. RESULTADOS: A prevalência do uso de drogas ilícitas entre gestantes foi de 18,28%. A regressão logística multivariada indicou como variáveis significativas: anos de estudo, participação em grupo de gestante e orientação de profissional de saúde quanto ao risco de usar drogas de abuso durante a gestação. CONCLUSÃO: Os resultados indicam a predominância de gestantes jovens, pardas, com baixa escolaridade e renda de até três salários mínimos e que faz uso de drogas de abuso, sendo que a mais utilizada o cigarro, seguido do álcool. As drogas ilícitas utilizadas foram a cocaína e seu derivado o crack e a maconha. Abstract in english OBJECTIVE: Determine the prevalence of drug abuse among pregnant women. METHOD: Cross-sectional study including 394 pregnant women who use the primary health care service. The dependent variable was the use of drugs during pregnancy and independent variables were: socioeconomic and obstetrics-relate [...] d data. RESULTS: The prevalence of drug abuse among pregnant women was 18.28%. Multivariate logistic regression indicates the following significant variables: years of education, participation in a pregnancy group and healthcare professional orientation as to the risk of using drugs during pregnancy. CONCLUSION: The results indicate the predominance of young mixed-race pregnant women, with low educational level, income of up to three minimum wages and who use drugs, the most common being cigarettes, followed by alcohol. Illegal drugs used were cocaine and its derivate, crack, as well as marihuana.
Bourgeois, A.; Henzel, D.; Malonga-Mouelet, G.; Dibanga, G.; Tsobou, C.; Peeters, M.; Delaporte, E.
OBJECTIVE: Sexually transmitted diseases (STDs) remain one of the major public health problems in the developing world. To implement a systematic screening of STDs among pregnant women in Libreville, Gabon, a preliminary cross sectional study on STD prevalence and risk factors was performed in antenatal clinics. A score, integrating risk factors and elementary clinical signs for the screening of STDs, showed higher performances compared with hierarchical algorithms. The prospective vali...
Raynor Pauline; Wright John; Toledano Mireille B; Smith Rachel B; Nieuwenhuijsen Mark J
Abstract Background Studies of disinfection by-products in drinking water and measures of adverse fetal growth have often been limited by exposure assessment lacking data on individual water use, and therefore failing to reflect individual variation in DBP exposure. Methods Pregnant women recruited to the Born in Bradford cohort study completed a questionnaire which covers water exposure. Information was collected on water consumption, showering, bathing and swimming. Water exposure data from...
Musa, Bolanle O. P.; Onyemelukwe, Geoffrey C; Olubunmi A. Olatunji; Kingsley O. Odogwu; Joseph O. Hambolu; Kene, Terfa S.
Background: Eclampsia, defined as the occurrence during pregnancy of hypertension, oedema, proteinuria and/or other neurologic abnormalities, causes substantial morbidity and mortality for both mother and foetus. However, its aetiology is largely unknown. Genetic and immune factors may play a role including a reduced maternal response to paternal antigen and an altered adaptation of the maternal immune system to the foetus. Methods: Participants consisted of pregnant women with and without a ...
Ana Paula B. de, Borborema-Alfaia; Norma Suely de Lima, Freitas; Spartaco, Astolfi Filho; Cristina Maria, Borborema-Santos.
Full Text Available There are limited data regarding prevalence of Chlamydia trachomatis infection among northern Brazilian pregnant women. OBJECTIVE: The purpose of this study was to estimate the prevalence of chlamydial infection among pregnant women in their third trimester and to determine the repercussion of this [...] infection on their offspring. METHODS: In the first phase of this study 100 pregnant women receiving prenatal care in a local public university hospital were examined to assess the prevalence of genital C. trachomatis infection by polymerase chain reaction technique. In the second phase, 88 pregnant women were prospectively evaluated for premature rupture of membranes, puerperal consequences associated with chlamydial infection, and neonates were checked for low-birth weight. RESULTS: The prevalence rate of chlamydial infection was 11%, and 72.7% of the positive participants were predominantly less than 30 years of age (p = 0.1319). A total of 36.4% of the participants had premature rupture of membranes (p = 0.9998). Neither low-birth weight infants nor preterm delivery were observed. A cohort of 16 newborn babies were followedup up to 60 days of life to ascertain outcome: 50% had respiratory symptoms. Neonates born to infected mothers had a higher risk to develop respiratory symptoms in the first 60 days of life. CONCLUSION: The scarcity of data about the effects of chlamydial infection on pregnancy and neonatal outcomes justified this study. Diagnosing and treating chlamydial infection during the third trimester of pregnancy may prevent neonate infection. Therefore, preventive screening should be seen as a priority for early detection of asymptomatic C. trachomatis infection as part of local public health strategies.
Dræbel, Tania; Gueth Kueil, Bill
Background Approximately 95% of South Sudan is malaria-endemic and transmission is high throughout the year. Annually, 2.3 million people are at risk of malarial infection, but children under 5 years, pregnant women and their unborn children are particularly at high risk. Appropriate policies for malarial prevention and control require a better understanding of the populations' malarial perceptions and treatment itinerary. Methods A qualitative study was carried out to explore malarial lay perce...
Holden, Kisha B.; McKenzie, Robetta; Pruitt, Vikki; Aaron, Katrina; Hall, Stephanie
This study examines the relationship between self-reported depressive symptoms, substance abuse and intimate partner violence among 602 African American, Hispanic, White, Asian American, American Indian/Alaskan Native, Native Hawaiian/Pacific Islander pregnant women who are clients of the Augusta Partnership for Children, Inc., a nonprofit collaborative that works with agencies, organizations, and individuals to improve the lives of children and families in Augusta-Richmond County, Georgia. D...
Long, Manhai; Knudsen, Ane-Kersti Skaarup; Pedersen, Henning Sloth; Bonefeld-Jørgensen, Eva Cecilie
The Greenlandic Inuit have high blood concentrations of environmental persistent organic pollutants (POPs). High POP concentrations have been associated with age, smoking and consumption of marine mammals. Studies have indicated that exposure to POPs during pregnancy may adversely affect fetal and child development. To assess geographical differences in diet, lifestyle and environmental contaminant exposure among pregnant women in Greenland, blood samples and questionnaire data were collected fr...
Guitard, Juliette; Andersen, Pernille; Ermont, Caroline; Gnidehou, Sedami; Fievet, Nadine; Lund, Ole; Deloron, Philippe; Tuikue Ndam, Nicaise
ABSTRACT: BACKGROUND: Pregnant women acquire protective antibodies that cross-react with geographically diverse placental Plasmodium falciparum isolates, suggesting that surface molecules expressed on infected erythrocytes by pregnancy-associated malaria (PAM) parasites have conserved epitopes and, that designing a PAM vaccine may be envisaged. VAR2CSA is the main candidate for a pregnancy malaria vaccine, but vaccine development may be complicated by its sequence polymorphism. METHODS: The dyna...
Guitard, Juliette; Andersen, Pernille; Ermont, Caroline; Gnidehou, Sedami; Fievet, Nadine; Lund, Ole; Deloron, Philippe; Ndam, Nicaise Tuikue
Background: Pregnant women acquire protective antibodies that cross-react with geographically diverse placental Plasmodium falciparum isolates, suggesting that surface molecules expressed on infected erythrocytes by pregnancy-associated malaria (PAM) parasites have conserved epitopes and, that designing a PAM vaccine may be envisaged. VAR2CSA is the main candidate for a pregnancy malaria vaccine, but vaccine development may be complicated by its sequence polymorphism. Methods: The dynamics of P....
Márcia Massumi, Okada; Luiza Akiko Komura, Hoga; Ana Luiza Vilela, Borges; Rosemeire Sartori de, Albuquerque; Maria Aparecida, Belli.
Full Text Available Resumo Objetivo: Caracterizar violência doméstica na gravidez. Métodos: Estudo transversal, exploratório e analítico da violência doméstica com 385 mulheres atendidas em maternidade pública. Testes de Qui-Quadrado de Pearson e Exato de Fisher foram utilizados para verificar associações e considerado [...] s significantes resultados p Abstract in english Abstract Objective: To characterize domestic violence in pregnancy. Method: Cross-sectional, exploratory and analytical study of domestic violence with 385 women who attended a public maternity. The Chi-square test of Pearson and Fisher exact test were used to verify associations and considering sig [...] nificant results p
Hanh, Nguyen Thi Thúy; Rasch, Vibeke
Women with HIV who want to have children face a range of challenges, quandaries, and hard decisions. This article examines the role of health staff in supporting HIV-infected pregnant women who desire to maintain their pregnancies. The article is derived from anthropological research conducted in Vietnam's Quang Ninh Province, an area that has a high HIV prevalence rate and is covered under the government's prevention of mother-to-child transmission program. The study included in-depth interviews with 23 HIV-infected women who had either recently given birth or were pregnant at the time of the research. Results showed that women were satisfied with the services they received from the program. The women believed that health care staff offered them not only medical care but also social and emotional support. The article concludes that the health care system is a vital point of support for pregnant women with HIV.
Full Text Available Abstract Background Effective interventions to prevent mother-to-child HIV transmission (PMTCT exist and when properly applied reduce the risk of vertical HIV transmission. As part of optimizing PMTCT in the Dutch Caribbean we developed a set of valid and applicable indicators in order to assess the quality of care in HIV-infected (pregnant women and their newborns. Methods A multidisciplinary expert panel of 19 experts reviewed and prioritized recommendations extracted from locally used international PMTCT guidelines according to a 3-step-modified-Delphi procedure. Subsequently, the feasibility, sample size, inter-observer reliability, sensitivity to change and case mixed stability of the potential indicators were tested for a data set of 153 HIV-infected women, 108 pregnancies of HIV-infected women and 79 newborns of HIV-infected women in Aruba, Curaçao and St Maarten from 2000 to 2010. Results The panel selected and prioritized 13 potential indicators. Applicability could not be tested for 4 indicators regarding HIV-screening in pregnant women because of lack of data. Four indicators performed satisfactorily for Curaçao ('monitoring CD4-cell count', 'monitoring HIV-RNA levels', 'intrapartum antiretroviral therapy and infant prophylaxis if antepartum antiretroviral therapy was not received', 'scheduled caesarean delivery' and 3 for St Maarten ('monitoring CD4-cell count', 'monitoring HIV-RNA levels', 'discuss and provide combined antiretroviral therapy to all HIV-infected pregnant women' whilst none for Aruba. Conclusions A systemic evidence-and consensus-based approach was used to develop quality indicators in 3 Dutch Caribbean settings. The varying results of the applicability testing accentuate the necessity of applicability testing even in, at first, comparable settings.
Shetty, Avinash K; Mhazo, Miriam; Moyo, Sostain; von Lieven, Andrea; Mateta, Patrick; Katzenstein, David A; Maldonado, Yvonne; Hill, David; Bassett, Mary T
The purpose of this pilot project was to assess the feasibility and acceptability of voluntary counselling and HIV testing (VCT) by pregnant women using community volunteers in Zimbabwe to prevent mother to child transmission (MTCT) of HIV. From July 1999 to June 2001, a short-course zidovudine (ZDV)-based perinatal HIV prevention programme was initiated in two antenatal clinics. Community volunteers, recruited from local community organizations, underwent a two-week training course in VCT, which included HIV/AIDS facts, systematic counselling approach, and practical counselling techniques using scripts and role-play. Rapid HIV testing was performed after informed consent. Lay counsellors conducted individual pre- and post-test counselling for HIV. A total of 35 women community volunteers were trained in VCT; 34 graduated and committed to work four hours per week in the clinic. Of the 6051 pregnant women presenting for antenatal clinics (ANC), 1824 (30%) underwent pre-test counselling and 1547 (26%) were tested, and 429 (28%) were HIV infected. Overall, 1283 (83%) returned for their test results including 406 (95%) of HIV-infected women. Of the 406 HIV-infected women who collected their test results, only 203 (50%) opted for ZDV prophylaxis to prevent MTCT of HIV. Over the two-year study period, two counsellors died and three sought employment at other organizations. Adherence to duty roster was 97% and no breach of confidentiality was reported. Despite many challenges, VCT delivered by community volunteers is feasible and acceptable for pregnant women aiming to reduce their risk of transmitting HIV to their infants. This programme is being implemented at several urban and rural MTCT sites in Zimbabwe and can serve as a model for other resource-poor countries. PMID:16303072
Bajc, Marika; Olsson, Berit; Joegi, Jonas [Skaane University Hospital and Lund University, Clinical Physiology and Nuclear Medicine, Lund (Sweden); Gottsaeter, Anders [Skaane University Hospital, Vascular Diseases, Malmoe (Sweden); Hindorf, Cecilia [Skaane University Hospital, Radiation Physics, Lund (Sweden)
The purpose of the study was to assess the prevalence of pulmonary embolism (PE) and other lung diseases among pregnant women with suspected PE and to calculate the radiation exposure to patient and fetus in this population. As a secondary aim, we evaluated the negative predictive value of a normal ventilation/perfusion single photon emission computed tomography (V/P SPECT) examination in pregnancy. We studied all 127 pregnant women who had suspected PE and had undergone V/P SPECT at our institution in the course of a 5-year period. Radiation exposure to patient and fetus and the negative predictive value of a normal V/P SPECT examination were also measured. V/P SPECT identified PE in 11 women (9 %). Moreover, in 15 women (12 %) the examination revealed pneumonia (in 2 cases in addition to PE) and in 1 woman signs of airway obstruction were revealed. Among the 116/127 women (91 %) where PE was ruled out by V/P SPECT, none was diagnosed subsequently with PE or deep venous thrombosis (DVT) during the same pregnancy or puerperal period. For P SPECT, the calculated fetal absorbed dose was < 0.6 mGy,and the calculated breast absorbed dose 0.6 mGy. For V SPECT, the calculated fetal absorbed dose was < 0.014 mGy and the breast absorbed dose 0.25 mGy. The prevalence of PE was low (9 %) among pregnant women with suspected disease. Pneumonia was diagnosed in 12 % of patients. The negative predictive value of V/P SPECT was high, and the radiation exposure from V/P SPECT was low both for fetus and patient. (orig.)
William, Kondo; Elaine Aparecida, Carraro; Elaine, Prandel; Josiane Mourão, Dias; Juliane, Perini; Rodolfo Lara de, Macedo; Taynah Cristina, Cornelsen; Renato, Sbalquiero; Maria das Graças, Sasaki.
Full Text Available Nevirapine-based therapy is associated with increased frequency of adverse events among HIV-infected pregnant women. The aim of this article was to evaluate the incidence of adverse effects in HIV-infected women who started nevirapine during pregnancy. A retrospective study was performed in our cent [...] er between January 2003 and December 2006 analyzing all women prescribed nevirapine during pregnancy. Women presenting any risk factor for hepatotoxicity were excluded from the analysis. Patients were divided into two groups according to the presence or absence of adverse effects, and a correlation to CD4 counts was performed. Liver function abnormality was graded according to the Division of AIDS toxicity guidelines. A total of 170 women initiated nevirapine during pregnancy, but only 133 were included in the study. Twenty-seven women (20.3%) presented adverse effects, skin rash accounting for 77.8% (21/27 women) and liver function abnormalities for 22.2% (6/27) of the cases. Baseline CD4 counts, viral loads and transaminases were similar in both groups. All nevirapine side effects were developed in less than seven weeks. Four of 31 women with CD4 counts 250 cells/µL (22.5%) developed adverse events. All patients who experienced hepatotoxicity had pretreatment CD4 counts >250cells/µL. The incidence of adverse events with nevirapine in our study was high, but most of them were cutaneous. There was no correlation between high CD4 counts and adverse events when analyzing both cutaneous and hepatic reactions; nevertheless, hepatotoxicity occurred only in pregnant women with CD4 counts >250cells/µL.
Pregnant women may not be arbitrarily excluded from participation in clinical cancer treatment trials. Exclusion of pregnant women from a particular trial must be based on a clear and compelling rationale or justification that shows that inclusion is inappropriate with respect to the health of the subjects or the purpose of the research, or other circumstances that offer a clear and compelling reason for exclusion.
Gowachirapant, S.; Winichagoon, P.; Wyss, L.; Tong, B.; Baumgartner, J.; Melse-Boonstra, A; Zimmermann, M. B.
The median urinary iodine concentration (UI) in school-aged children is recommended for assessment of iodine nutrition in populations. If the median UI is adequate in school-aged children, it is usually assumed iodine intakes are also adequate in the remaining population, including pregnant women. But iodine requirements sharply increase during pregnancy. In this study, our aim was to measure UI in pairs of pregnant women and their school-aged children from the same family, who were sharing m...
Beheshteh Olang; Zahra Abdollahi; Roshanak Neshati; Mohamed Atiya Ali; Mohsen Naghavi; Agneta Yngve
Background: Vitamin A deficiency is considered as one of the public health problems among pregnant women worldwide. Population representative data on vitamin A status in pregnancy have not previously been published from Iran. Objectives: The aim of this study was to publish data on vitamin A status in pregnant women in all the provinces of Iran in 2001, including urban and rural areas, and to describe the association of vitamin A status with maternal age, gestational age, and parity. Design: ...
Mwambe, Berno; Mshana, Stephen E.; Kidenya, Benson R.; Massinde, Anthony N; Humphrey D Mazigo; Michael, Denna; Majinge, Charles; Groß, Uwe
Abstract Background Serological screening of pregnant women for Toxoplasma gondii-specific antibodies is not practiced as an antenatal care in Tanzania; and there is a limited data about sero-prevalence of T. gondii infection in developing countries. We therefore conducted this study to determine the sero-prevalence and factors associated with T. gondii infection among pregnant women attending antenatal care clinics in Mwanza, Tanzania. Methods Between 1st November 2012 and 31st May 2013 a to...
Abbas Rahim Foroushani; Farzad Shidfar; Vahid Mofid; Mansoreh Samimi; Shima Jazayeri; Mohammad Najafi; Zatollah Asemi; Mohamad Esmaiel Shahaboddin
Previous studies have shown that inflammatory factors increases in pregnancy and is associated with several complications of pregnancy. The aim of this study was to assess effects of daily consumption of probiotic yoghurt on inflammatory factors in pregnant women. In a randomized clinical trial, seventy primigravid (the first pregnancy) and singleton pregnant women aged 18-30 years were assigned to two groups. Subjects consumed daily 200 g probiotic yoghurt containing Lactobacillus acidophilu...
Manyando Christine; Mkandawire Rhoda; Puma Lwipa; Sinkala Moses; Mpabalwani Evans; Njunju Eric; Gomes Melba; Ribeiro Isabela; Walter Verena; Virtanen Mailis; Schlienger Raymond; Cousin Marc; Chipimo Miriam; Sullivan Frank M
Abstract Background Safety data regarding exposure to artemisinin-based combination therapy in pregnancy are limited. This prospective cohort study conducted in Zambia evaluated the safety of artemether-lumefantrine (AL) in pregnant women with malaria. Methods Pregnant women attending antenatal clinics were assigned to groups based on the drug used to treat their most recent malaria episode (AL vs. sulphadoxine-pyrimethamine, SP). Safety was assessed using standard and pregnancy-specific para...
Bankole Henry Oladeinde; Richard Omoregie; Ikponmwosa Odia; Oladapo Babatunde Oladeinde
Objectives: To determine the prevalence of malaria and anemia among pregnant women attending a traditional birth center as well as the effect of herbal remedies, gravidity, age, educational background and malaria prevention methods on their prevalence.Methods: Blood specimens were collected from 119 pregnant women attending a Traditional Birth Home in Benin City, Nigeria. Malaria parasitemia was diagnosed by microscopy while anemia was defined as hemoglobin concentration
Banda Shalini Reddy; NeelkantReddy Patil; Hinchageri S. S; Swarna kamala
In the present study an attempt is made to assess the pattern of drug use among pregnant women and to evaluate the impact of counseling on medication adherence by providing patient education regarding pregnancy. During the study period pregnant women were enrolled in the study after obtaining consent from them. The prescriptions containing atleast one drug were analyzed and the drugs prescribed were classified according to their pharmacological class. Analysis of prescription patterns did not...
Gebremichael Lemlem Gebremedhin; Gomathi, P
Objectives: To assess the extent and nature of drug utilization among pregnant women attending antenatal care in hospitals of Mekelle, Tigray, Ethiopia. Methods: Institution-based cross sectional study was conducted by reviewing the antenatal care follow up cards and interviewing pregnant women using semi-structured questionnaire by nurses working in the four hospitals. Details of drugs self utilized and prescribed during the current pregnancy were investigated and categorized according t...
Boatin, Adeline A; Wylie, Blair; Goldfarb, Ilona; Azevedo, Robin; Pittel, Elena; Ng, Courtney; Haberer, Jessica
We tested functionality and acceptability of a wireless fetal monitoring prototype technology in pregnant women in an inpatient labor unit in the United States. Women with full-term singleton pregnancies and no evidence of active labor were asked to wear the prototype technology for 30 minutes. We assessed functionality by evaluating the ability to successfully monitor the fetal heartbeat for 30 minutes, transmit this data to Cloud storage and view the data on a web portal. Three obstetricians also rated fetal cardiotocographs on ease of readability. We assessed acceptability by administering closed and open-ended questions on perceived utility and likeability to pregnant women and clinicians interacting with the prototype technology. Thirty-two women were enrolled, 28 of whom (87.5%) successfully completed 30 minutes of fetal monitoring including transmission of cardiotocographs to the web portal. Four sessions though completed, were not successfully uploaded to the Cloud storage. Six non-study clinicians interacted with the prototype technology. The primary technical problem observed was a delay in data transmission between the prototype and the web portal, which ranged from 2 to 209 minutes. Delays were ascribed to Wi-Fi connectivity problems. Recorded cardiotocographs received a mean score of 4.2/5 (± 1.0) on ease of readability with an interclass correlation of 0.81(95%CI 0.45, 0.96). Both pregnant women and clinicians found the prototype technology likable (81.3% and 66.7% respectively), useful (96.9% and 66.7% respectively), and would either use it again or recommend its use to another pregnant woman (77.4% and 66.7% respectively). In this pilot study we found that this wireless fetal monitoring prototype technology has potential for use in a United States inpatient setting but would benefit from some technology changes. We found it to be acceptable to both pregnant women and clinicians. Further research is needed to assess feasibility of using this technology in busy inpatient settings. PMID:25622043
Money, Deborah M.; Wagner, Emily C.; Maan, Evelyn J.; Chaworth-Musters, Tessa; Gadawski, Izabelle; van Schalkwyk, Julie E.; Forbes, John C.; Burdge, David R.; Albert, Arianne Y. K.; Lohn, Zoe; Côté, Hélène C. F.
Introduction Combination antiretroviral therapy (cART) can effectively prevent vertical transmission of HIV but there is potential risk of adverse maternal, foetal or infant effects. Specifically, the effect of cART use during pregnancy on mitochondrial DNA (mtDNA) content in HIV-positive (HIV+) women is unclear. We sought to characterize subclinical alterations in peripheral blood mtDNA levels in cART-treated HIV+ women during pregnancy and the postpartum period. Methods This prospective longitudinal observational cohort study enrolled both HIV+ and HIV-negative (HIV-) pregnant women. Clinical data and blood samples were collected at three time points in pregnancy (13-<23 weeks, 23-<30 weeks, 30–40 weeks), and at delivery and six weeks post-partum in HIV+ women. Peripheral blood mtDNA to nuclear DNA (nDNA) ratio was measured by qPCR. Results Over a four year period, 63 HIV+ and 42 HIV- women were enrolled. HIV+ women showed significantly lower mtDNA/nDNA ratios compared to HIV- women during pregnancy (p = 0.003), after controlling for platelet count and repeated measurements using a multivariable mixed-effects model. Ethnicity, gestational age (GA) and substance use were also significantly associated with mtDNA/nDNA ratio (p?0.02). Among HIV+ women, higher CD4 nadir was associated with higher mtDNA/nDNA ratios (p<0.0001), and these ratio were significantly lower during pregnancy compared to the postpartum period (p<0.0001). Conclusions In the context of this study, it was not possible to distinguish between mtDNA effects related to HIV infection versus cART therapy. Nevertheless, while mtDNA levels were relatively stable over time in both groups during pregnancy, they were significantly lower in HIV+ women compared to HIV- women. Although no immediate clinical impact was observed on maternal or infant health, lower maternal mtDNA levels may exert long-term effects on women and children and remain a concern. Improved knowledge of such subclinical alterations is another step toward optimizing the safety and efficacy of cART regimens during pregnancy. PMID:26247211
García Heredia, M; García, S D; Copolillo, E F; Cora Eliseth, M; Barata, A D; Vay, C A; de Torres, R A; Tiraboschi, N; Famiglietti, A M R
Pregnant women are more susceptible to both vaginal colonization and infection by yeast. Our objectives were to determine the prevalence in pregnant women of yeasts isolated from vaginal exudates and their susceptibility to current antifungal drugs. A total of 493 patients was studied between December 1998 and February 2000. The prevalence of Candida spp. was 28% (Candida albicans 90.4%; Candida glabrata 6.3%; Candida parapsilosis 1.1%, Candida kefyr 1.1 %; unidentified species 1.1 %). The diffusion test in Shadomy agar was employed to determine the susceptibility to fluconazole, ketoconazole, itraconazole and nistatine. All C. albicans, C. kefyr and C. parapsilosis isolates were susceptible in vitro to the antifungal agents tested, while 1 in 6 C. glabrata isolates showed resistance to azole drugs; all strains were susceptible to nistatine. In pregnant women, C. albicans was the yeast most frequently isolated from vaginal exudates; it continues to be highly susceptible to antifungal drugs. Azole resistance was detected only among C. glabrata isolates. Identification to the species level is recommended, specially in cases of treatment failure and recurrent or chronic infection. PMID:16784126
Full Text Available Group B Streptococcus (GBS is one of the most important bacteria in the majority of maternal and neonatal infections, such as chorioamnionitis, endometritis, bacteremia, sepsis and meningitis. During pregnancy, GBS screening is one of the recommended strategies that are recommended by center of disease control (CDC. This study was aimed to determine the rectovaginal colonization prevalence among pregnant women, and also the rate of transmission to their offspring. Between June 2008 and April 2009, two hundred pregnant women admitted in department of Obstetrics and Gynecology (Ghaem Hospital, Mashhad, Iran were enrolled in present study. Samples from maternal rectum and vagina as well as neonate ear and umbilical cord were taken for culture. The colonization rate for GBS in pregnant women and their neonates was around 6% and 5% respectively. All the carrier mothers were cases with premature rupture of membranes (at least 18 hours before delivery. In terms of colonization, there was a significant correlation between mothers and newborns, and more than 80% of neonates from GBS carrier mothers were colonized by GBS
Lindhardt, Christina Louise; Rubak, Sune
OBJECTIVE: to explore and describe how healthcare professionals in the Southern Region of Denmark experienced motivational interviewing as a communication method when working with pregnant women with obesity. DESIGN: a qualitative, descriptive study based on face-to-face interviews with 11 obstetric healthcare professionals working in a perinatal setting. METHODS: a thematic descriptive method was applied to semi-structured interviews. The healthcare professional?s experiences were recorded verbatim during individual semi-structured qualitative interviews, transcribed, and analysed using a descriptive analysis methodology. FINDINGS: motivational interviewing was found to be a useful method when communicating with obese pregnant women. The method made the healthcare professionals more aware of their own communication style both when encountering pregnant women and in their interaction with colleagues. However, most of the healthcare professionals emphasised that time was crucial and they had to be dedicatedto the motivational interviewing method. The healthcare professionals further stated that it enabled them to become more professional in their daily work and made some of them feel less 'burned out', 'powerless' and 'stressed' as they felt they had a communication method in handling difficult workloads. CONCLUSION: healthcare professionals experienced motivational interviewing to be a useful method when working perinatally. The motivational interviewing method permitted heightened awareness of the healthcare professionals communication method with the patients and increased their ability to handle a difficult workload. Overall, lack of time restricted the use of the motivational interviewing method on a daily basis.
Objective: To study the relationships between plasma adrenomedullin (ADM) and normal pregnancy and pathogenesis of pregnancy-induced hypertension (PIH). Methods: ADM concentrations in the plasma from 10 normal non-pregnant women, 36 normal pregnant women (12 first, 12 second, 12 third trimester, respectively) and 30 cases of PIH (10 mild, 10 moderate, 10 severe, respectively) were determined by radioimmunoassay, and data were analyzed statistically. Results: ADM concentrations in the first, second and third trimester of normal pregnancy increased significantly than that of normal non-pregnant women (P<0.05). ADM concentration in the plasma of patients with PIH was higher than that of third trimester pregnancy (P<0.01). There were significant differences between mild, moderate, and severe PIH groups (P<0.05). In the PIH groups, significant positive correlation was found between plasma ADM concentration and mean arterial pressure (r=0.822, P<0.05). Incidence of low birth weight infants was related to serious degree of PIH. Conclusion: ADM may involve in maintaining normal human pregnancy. ADM may increase compensatorily in the pathogenesis of PIH
Usselman, Charlotte W; Wakefield, Paige K; Skow, Rachel J; Stickland, Michael K; Chari, Radha S; Julian, Colleen G; Steinback, Craig D; Davenport, Margie H
Baseline neurovascular transduction is reduced in normotensive pregnancy; however, little is known about changes to neurovascular transduction during periods of heightened sympathetic activation. We tested the hypothesis that, despite an exacerbated muscle sympathetic nerve activity (microneurography) response to cold pressor stimulation, the blunting of neurovascular transduction in normotensive pregnant women would result in similar changes in vascular resistance and mean arterial pressure (Finometer) relative to nonpregnant controls. Baseline neurovascular transduction was reduced in pregnant women relative to controls when expressed as the quotient of both total resistance and mean arterial pressure and sympathetic burst frequency (0.32±0.07 versus 0.58±0.16 mm Hg/L/min/bursts/min, Pinduced sympathoexcitation remained blunted in pregnant women (0.25±0.11 versus 0.45±0.08 mm Hg/L/min/bursts/min, Ppregnancy is associated with reductions in neurovascular transduction, which result in the dissociation of sympathetic outflow from hemodynamic outcomes, even during cold pressor-induced sympathoexcitation. PMID:26259593
de Holanda, Eliane Rolim; Galvão, Marli Teresinha Gimeniz; Pedrosa, Nathália Lima; Paiva, Simone de Sousa; de Almeida, Rosa Lívia Freitas
OBJECTIVES: to analyze the spatial distribution of reported cases of pregnant women infected by the human immunodeficiency virus and to identify the urban areas with greater social vulnerability to the infection among pregnant women. METHOD: ecological study, developed by means of spatial analysis techniques of area data. Secondary data were used from the Brazilian National Disease Notification System for the city of Recife, Pernambuco. Birth data were obtained from the Brazilian Information System on Live Births and socioeconomic data from the 2010 Demographic Census. RESULTS: the presence of spatial self-correlation was verified. Moran's Index was significant for the distribution. Clusters were identified, considered as high-risk areas, located in grouped neighborhoods, with equally high infection rates among pregnant women. A neighborhood located in the Northwest of the city was distinguished, considered in an epidemiological transition phase. CONCLUSION: precarious living conditions, as evidenced by the indicators illiteracy, absence of prenatal care and poverty, were relevant for the risk of vertical HIV transmission, converging to the grouping of cases among disadvantaged regions. PMID:26155005
Meireles, Juliana Fernandes Filgueiras; Neves, Clara Mockdece; de Carvalho, Pedro Henrique Berbert; Ferreira, Maria Elisa Caputo
The body image of pregnant women is an issue that should be further investigated by professionals in the area, especially in view of the fact that maternal and infant health has gained such prominence. The scope of this integrative review is to analyze the literature relating to body image and body dissatisfaction among pregnant women. Research was based on articles extracted from the Scopus, PubMed, BVS and PsycINFO databases, by cross-referencing "pregnancy" with the keywords "body image" and "body dissatisfaction." Once the inclusion and exclusion criteria had been adopted, forty studies were analyzed. These produced inconclusive data about body dissatisfaction during pregnancy. Symptoms of depression, low self-esteem, an inadequate approach towards healthy eating and weight gain above recommended limits have been associated with a negative body image. The contradictory findings could be related to the different instruments used to measure body image. In view of the possible impact that a negative body image can have on maternal and infant health during pregnancy, it is recommended that further investigations are made, in particular related to the development of a specific tool to evaluate the body image of pregnant women. PMID:26132248
Izquierdo Alvarez, Silvia; Castañón, Sandra García; Ruata, Maria Luisa Calvo; Aragüés, Elena Fuertes; Terraz, Pilar Bocos; Irazabal, Yolanda González; González, Elena García; Rodríguez, Beatriz García
Selenium, copper and zinc status is important in pregnant women. The aim of this study was to establish updated normal ranges for these elements in serum of pregnant women from the Spanish region of Aragon, and to study variation in levels with respect to gestational period and maternal age. The study group consisted of 159 pregnant women who did not suffer from serious pathologies. These samples were classified into four gestational-period groups. Zn and Cu determinations were obtained by flame atomic absorption spectroscopy in a Perkin-Elmer 1100B apparatus, and Se was determined by electrothermal atomic absorption spectrometry with Zeeman correction, in a Perkin-Elmer 4110 ZL apparatus. The concentrations of Cu, Zn and Se averaged 73.61+/-43.67 microg/dL, 65.37+/-12.87 microg/dL and 99.59+/-21.74 microg/L, respectively. The Cu/Zn ratio increased from first trimester to the third trimester (2.07-3.49). There was no significant correlation between Zn and Se levels, but a significant correlation was found between Cu and Se levels (p<0.05) and between Cu and Zn levels (p<0.001). Serum Zn and Se levels decreased over gestation, while serum Cu concentrations increased; in all cases the variation occurred mostly in the first 3 or 4 months, with mean levels then remaining fairly stable until the end of pregnancy. Maternal age did not influence levels of any of the three metals. PMID:18039497
Karla A. Bascuñán
Full Text Available Chilean diets are characterized by a low supply of n-3 polyunsaturated fatty acids (n-3 PUFA, which are critical nutrients during pregnancy and lactation, because of their role in brain and visual development. DHA is the most relevant n-3 PUFA in this period. We evaluated the dietary n-3 PUFA intake and erythrocyte phospholipids n-3 PUFA in Chilean pregnant women. Eighty healthy pregnant women (20–36 years old in the 3rd–6th month of pregnancy were included in the study. Dietary assessment was done applying a food frequency questionnaire, and data were analyzed through the Food Processor SQL® software. Fatty acids of erythrocyte phospholipids were assessed by gas-liquid chromatography. Diet composition was high in saturated fat, low in mono- and PUFA, high in n-6 PUFA (linoleic acid and low in n-3 PUFA (alpha-linolenic acid and DHA, with imbalance in the n-6/n-3 PUFA ratio. Similar results were observed for fatty acids from erythrocyte phospholipids. The sample of Chilean pregnant women showed high consumption of saturated fat and low consumption of n-3 PUFA, which is reflected in the low DHA content of erythrocyte phospholipids. Imbalance between n-6/n-3 PUFA could negatively affect fetal development. New strategies are necessary to improve n-3 PUFA intake throughout pregnancy and breast feeding periods. Furthermore, it is necessary to develop dietary interventions to improve the quality of consumed foods with particular emphasis on n-3 PUFA.
Maria Clerya Alvino Leite, Maria Mirtes da Nóbrega, Maria Miriam Lima da Nóbrega
Full Text Available Objective: to elaborate the profile of nursing diagnoses in pregnant women assisted in a Family’s Health Unit based on NANDA-I’s Taxonomy II. Methods: this is about a retrospective study, analytic descriptive, regards to analysis from 20 pregnant women handbooks registered in the prenatal program from a family’s health unit. Data were collected in July 2008, with a form composed of three parts: partner-demographic data, obstetric data and referring data to defining characteristics and related factors (of risk of the nursing diagnoses. Diagnoses were analyzed based on the descriptive statistics and discussed according to obstetrics references. Results: 13 nursing diagnoses were elaborated: risk for infection of the genital tract, ineffective maintenance of the health, risk for infection of the urinary tract, prejudiced urinary elimination, nauseas, sharp pain (head, pelvis and lumbar, fatigues, insomnia, sexual dysfunction, risk of paternity or prejudiced maternity, volume of excessive liquid, constipation, anxiety. Conclusion: the objective of the study was researched and we hope from the nursing diagnoses elaborated, some nursing interventions specific be addressed to the problems identified in the pregnant women during the prenatal consultations.