WorldWideScience
1

Dynamic Weapon-Target Assignment Problems with ...  

Science.gov (United States)

... defense's weapons are Space-based kinetic-kill vehicles ... I ti I obtained by dividing the weapons as ... of the optimal weapon-arge assigntments and ...

1988-06-01

2

Host plant shifts affect a major defense enzyme in Chrysomela lapponica  

UK PubMed Central (United Kingdom)

Chrysomelid leaf beetles use chemical defenses to overcome predatory attack and microbial infestation. Larvae of Chrysomela lapponica that feed on willow sequester plant-derived salicin...Full Text Available

2011-03-22

3

Investigation of the effect of laundering the ground crew chemical defense overgarment on toxic-free-area vapor transfer during shelter entry by initially contaminated personnel. Interim report, Oct 87-Jan 88  

Energy Technology Data Exchange (ETDEWEB)

A study by the U.S. Air Force School of Aerospace Medicine, Brooks AFB, Texas, has compared the shelter processing transfer of chemical warfare agent simulant vapor for subjects wearing unwashed and laundered ground-crew chemical defense overgarments. Twice laundered and four times laundered protective garments were included in the assessment. Test subjects, wearing the unwashed and laundered protective garments were initially sprayed with liquid simulant (methyl salicylate) to a target density of 5 g m-2. They were then sequentially processed into and through the USAFSAM Collective Protection Shelter (SCPS-2B) test facility. Immediately upon entry to the Toxic-Free Area, the subjects were confined in individual off gassing booths for 2 h while offgassed simulant vapor concentration in the booths was recorded. The resulting mean maximum vapor concentrations recorded in the booths for subjects who had ...

1990-12-01

4

Chemical Defense and the Persistence of Pioneer Plant Seeds in the Soil of a Tropical Cloud Forest:  

British Library Electronic Table of Contents (United Kingdom)

ABSTRACT We present evidence that differences in soil seedbank persistence among pioneer plants in the cloud forest of Monteverde, Costa Rica, are influenced by differences in seed chemical defense. We used extracted seed chemicals from Bocconia frutescens (Papaveraceae), Guettarda poasana (Rubiaceae), Phytolacca rivinoides (Phytolaccaceae), Urera elata (Urticaceae), Cecropia polyphlebia (Cecropiaceae), and Witheringia meiantha (Solanaceae) to assess seed chemical defense in two ways: (1) a plant pathogen inhibition assay using Pythium irregulare; and (2) a brine shrimp toxicity assay using Artemia salina. The combined performance of each species in the two assays positively correlated with seedbank persistence. In the pathogen assay, mycelium growth was reduced when Pythium was cultured o...

2007-01-01

5

Insect-Induced Conifer Defense. White Pine Weevil and Methyl Jasmonate Induce Traumatic Resinosis, de Novo Formed Volatile Emissions, and Accumulation of Terpenoid Synthase and Putative Octadecanoid Pathway Transcripts in Sitka Spruce1[w  

UK PubMed Central (United Kingdom)

Stem-boring insects and methyl jasmonate (MeJA) are thought to induce similar complex chemical and anatomical defenses in conifers. To compare insect- and MeJA-induced terpenoid responses, we analyzed...Full Text Available

2005-01-01

6

Approaches to the evaluation of chemical-induced immunotoxicity.  

UK PubMed Central (United Kingdom)

The immune system plays a crucial role in maintaining health; however, accumulating evidence indicates that this system can be the target for immunotoxic effects caused by a variety of chemicals including...Full Text Available

1995-12-01

7
8

Detection device for high explosives  

Energy Technology Data Exchange (ETDEWEB)

A portable fiber optic detector that senses the presence of specific target chemicals by electrostatically attracting the target chemical to an aromatic compound coating on an optical fiber. Attaching the target chemical to the coated fiber reduces the fluorescence so that a photon sensing detector records the reduced light level and activates an appropriate alarm or indicator.

1992-01-01

9

Target area chamber system design for the National Ignition Facility  

International Nuclear Information System (INIS)

The National Ignition Facility (NIF) is a proposed Department of Energy facility which will contribute to the resolution of important Defense Program and inertial fusion energy issues for energy production in the future. The NIF will consist of a laser system with 192 independent beamlets transported to a target chamber. The target chamber is a multi-purpose structure that provides the interface between the target and the laser optics. The chamber must be capable of achieving moderate vacuum levels in reasonable times; it must remain dimensionally stable within micron tolerances, provide support for the optics, diagnostics, and target positioner; it must minimize the debris from the x-ray and laser light environments; and it must be capable of supporting external neutron shielding. The chamber must also be fabricated from a low neutron activation material. The fusion reaction in the ...

1994-06-19

10

Attack Methodology Analysis: Emerging Trends in Computer-Based Attack Methodologies and Their Applicability to Control System Networks  

Energy Technology Data Exchange (ETDEWEB)

Threat characterization is a key component in evaluating the threat faced by control systems. Without a thorough understanding of the threat faced by critical infrastructure networks, adequate resources cannot be allocated or directed effectively to the defense of these systems. Traditional methods of threat analysis focus on identifying the capabilities and motivations of a specific attacker, assessing the value the adversary would place on targeted systems, and deploying defenses according to the threat posed by the potential adversary. Too many effective exploits and tools exist and are easily accessible to anyone with access to an Internet connection, minimal technical skills, and a significantly reduced motivational threshold to be able to narrow the field of potential adversaries effectively. Understanding how hackers evaluate new IT security research and incorporate significant new ideas into their own tools provides ...

2005-06-01

11

Comparative genomics of insect juvenile hormone biosynthesis?  

UK PubMed Central (United Kingdom)

The biosynthesis of insect juvenile hormone (JH) and its neuroendocrine control are attractive targets for chemical control of insect pests and vectors of disease. To facilitate the molecular...Full Text Available

2006-04-01

12

Defense Science Board Task Force on Technology Investment for the Defense Advanced Research Projects Agency (DARPA).  

Science.gov (United States)

As requested by the Under Secretary of Defense (Acquisition, Technology, and Logistics) and the Director DARPA, the Defense Science Board task force performed a one-time independent evaluation of the technology investment for the Defense Advanced Research...

2003-01-01

13

Responses of Bark Beetle-Associated Bacteria to Host Monoterpenes and Their Relationship to Insect Life Histories  

British Library Electronic Table of Contents (United Kingdom)

Bark beetles that colonize living conifers and their microbial associates encounter constitutive and induced chemical defenses of their host. Monoterpene hydrocarbons comprise a major component of these allelochemicals, and many are antibiotic to insects, fungi, and bacteria. Some bark beetle species exhaust these defenses by killing their host through mass attacks mediated by aggregation pheromones. Others lack adult aggregation pheromones and do not engage in pheromone-mediated mass attacks, but rather have the ability to complete development within live hosts. In the former species, the larvae develop in tissue largely depleted of host terpenes, whereas in the latter exposure to these compounds persists throughout development. A substantial literature exists on how monoterpenes affect b...

2011-01-01

14

Genetic Variation of Lodgepole Pine, Pinus contorta var. latifolia, Chemical and Physical Defenses that Affect Mountain Pine Beetle, Dendroctonus ponderosae, Attack and Tree Mortality  

British Library Electronic Table of Contents (United Kingdom)

Plant secondary chemistry is determined by both genetic and environmental factors, and while large intraspecific variation in secondary chemistry has been reported frequently, the levels of genetic variation of many secondary metabolites in forest trees in the context of potential resistance against pests have been rarely investigated. We examined the effect of tree genotype and environment/site on the variation in defensive secondary chemistry of lodgepole pine, Pinus contorta var. latifolia, against the fungus, Grosmannia clavigera (formerly known as Ophiostoma clavigerum), associated with the mountain pine beetle, Dendroctonus ponderosae. Terpenoids were analyzed in phloem samples from 887, 20-yr-old trees originating from 45 half-sibling families planted at two sites. Samples were coll...

2011-01-01

15

Malnutrition, Gut-Microbial Interactions and Mucosal Immunity to Vaccines, 07 Nov 2011 - 11 Nov 2011, Le Meridien New Delhi, New Delhi, India - SciDe  

Wastenet

... A better understanding of the links between nutrients, the gut microbiome and the intestinal immune system is likely to pave the way to the development of innovative approaches that target activation of specific immunological pathways for promoting the hostrsquo;s gut defense. Such knowledge should positively impact on the development of vaccine formulations and intervention strategies for improved control of enteric infections in developing countries. Registration fees # The Registration Fee is $715.00 on and before September 7, 2011. # After September 7, 2011, the ...

16

Studies on the biological effects of chemical defense mechanisms in vivo activated by low-dose irradiation  

International Nuclear Information System (INIS)

Active oxygens produced by low-dose irradiation can induce the synthesis of proteins involved in the active oxygen reduction path and can activate the chemical self-defense mechanisms in vivo, which can alleviate the injuries caused by active oxygens themselves. The following findings suggests that it is not only by low-dose irradiation that can induce the responses described above but also by any physical and/or chemical stresses which can produce small amount of active oxygens in vivo. 1. X-irradiation with 0.5 Gy and/or water immersion and restraint induced heat shock protein (HSP)70 in rat stomach cells. HSP70 was also induced in adrenal cells by paraquat administration. 2. The SOD activity in pancreas of rat significantly increased by #gamma#-irradiation with 0.5 Gy. 0.5 Gy irradiation preceeding the alloxan administration significantly suppressed the increase in pancreatic lipid peroxides and in blood glucose levels, ...

17

Update of the Navy Contract Writing Guide Phase III  

Science.gov (United States)

... Defense Finance and Accounting Service DID Data Item Descriptions DLA Defense Logistics Agency DLAM Defense Logistics Agency Manual ...

2005-06-01

19

Network Security Defense Tools  

Science.gov (United States)

Lecturo on Firewalls, VPNs, Intrusion Detection, and filters

2009-02-11

20

Thermal stress imposed by prototype bilayer and current ground crew chemical defense ensembles: a limited laboratory comparison. Final report, 30 June 1986-1 January 1987  

Energy Technology Data Exchange (ETDEWEB)

An open bilayer ground-crew chemical defense ensemble (CDE) was proposed to reduce the thermal burden during vapor-only exposure periods. This study compared the thermal-stress profile of the proposed ensemble to that produced by the currently employed closed CDE. Four subjects, alternating ensembles on separate days, walked on a treadmill in an environmental chamber at 5.3 km/h (3.3 mph) and 2% grade (an energy expenditure of 350 kcal/h) for alternating work/rest to achieve significant recovery. Mean total sweat production was lower (1.38 vs. 2.50 liters) and percent sweat evaporation greater (65.7% vs. 30.0%) in the prototype ensemble than in the CDE. The prototype ensemble provided greater heat dissipation and allowed more-efficient sweat evaporation which had the double benefit of reducing heat storage and limiting dehydration.

1988-07-01

21

Nuclear waste form risk assessment for US defense waste at Savannah River Plant. Annual report fiscal year 1980  

Energy Technology Data Exchange (ETDEWEB)

Waste form dissolution studies and preliminary performance analyses were carried out to contribute a part of the data needed for the selection of a waste form for the disposal of Savannah River Plant defense waste in a deep geologic repository. The first portion of this work provides descriptions of the chemical interactions between the waste form and the geologic environment. We reviewed critically the dissolution/leaching data for borosilicate glass and SYNROC. Both chemical kinetic and thermodynamic models were developed to describe the dissolution process of these candidate waste forms so as to establish a fundamental basis for interpretation of experimental data and to provide directions for future experiments. The complementary second portion of this work is an assessment of the impacts of alternate waste forms upon the consequences of disposal in various proposed geological media. Employing systems analysis ...

1981-07-01

22

Environmentally-Induced Malignancies: An In Vivo Model to Evaluate the Health Impact of Chemicals in Mixed Waste  

Energy Technology Data Exchange (ETDEWEB)

Occupational and environmental exposure to organic ligands, solvents, fuel hydrocarbons, and polychlorinated biphenyls are linked with increased risk of hematologic malignancies. DOE facilities and waste sites in the U.S. are contaminated with mixtures of potentially hazardous chemicals such as metals, organic ligands, solvents, fuel hydrocarbons, polychlorinated biphenyls and radioactive isotopes. A major goal of this project was to establish linkage between chemical/radiation exposure and induction of genomic damage in target populations with the capability to undergo transformation.

2001-05-04

23

Biological and Chemical Security  

Science.gov (United States)

The LLNL Chemical & Biological National Security Program (CBNP) provides science, technology and integrated systems for chemical and biological security. Our approach is to develop and field advanced strategies that dramatically improve the nation's capabilities to prevent, prepare for, detect, and respond to terrorist use of chemical or biological weapons. Recent events show the importance of civilian defense against terrorism. The 1995 nerve gas attack in Tokyo's subway served to catalyze and focus the early LLNL program on civilian counter terrorism. In the same year, LLNL began CBNP using Laboratory-Directed R&D investments and a focus on biodetection. The Nunn-Lugar-Domenici Defense Against Weapons of Mass Destruction Act, passed in 1996, initiated a number of U.S. nonproliferation and counter-terrorism programs including the DOE (now NNSA) ...

2002-12-19

24

Explosives sensor  

Energy Technology Data Exchange (ETDEWEB)

A compact and supersensitive device that can rapidly detect minute trace vapors from concealed explosives has been developed by scientists at Oak Ridge National Laboratory (ORNL). The new explosives sensor can detect and chemically identify organic nitrogen-oxygen compounds which are the building blocks of explosives such as TNT, plastiques, and nitroglycerine. The device could be used to scan persons entering airport terminals, nuclear power plants, defense installations, or other sensitive locations, providing greater security against potential terrorism. This device works on a glow discharge principle, and is more specifically called an ''Atmospheric Sampling Glow Discharge Ionization'' (ASGDI) source. The new detector is a highly automated, miniaturized version of research mass spectrometers widely used to trace constituents of chemical mixtures. Detail of this device's ...

1987-01-01

25

Report on NCI symposium: comparison of mechanisms of carcinogenesis by radiation and chemical agents. II. Cellular and animal models  

International Nuclear Information System (INIS)

The point at which the common final pathway for induction of cancer by chemical carcinogens and ionizing radiation has not been identified. Although common molecular targets are suggested by recent findings about the role of oncogenes, the mechanism by which the deposition of radiation energy and the formation of adducts or other DNA lesions induced by chemicals affects the changes in the relevant targets may be quite different. The damage to DNA that plays no part in the transformation events, but that influences the stability of the genome, and therefore, the probability of subsequent changes that influence tumorigenesis may be more readily induced by some agents than others. Similarly, the degree of cytotoxic effects that disrupt tissue integrity and increase the probability of expression of initiated cells may be dependent on the type of carcinogen. Also, evidence was presented that repair of the ...

1984-05-20

26

Target organs and systems: methodologies to assess immune system function.  

UK PubMed Central (United Kingdom)

Immunotoxicity encompasses both reduced and heightened immune function. Diverse chemicals can impair functioning of the immune system. Both monographs and books have been devoted to detailed descriptions...Full Text Available

1998-04-01

27

Gyrase B Inhibitor Impairs HIV-1 Replication by Targeting Hsp90 and the Capsid Protein*  

UK PubMed Central (United Kingdom)

Chemical genetics is an emerging approach to investigate the biology of host-pathogen interactions. We screened several inhibitors of ATP-dependent DNA motors and detected the gyrase B inhibitor coumermycin...Full Text Available

2010-12-10

28

Cumulative effects of in utero administration of mixtures of reproductive toxicants that disrupt common target tissues via diverse mechanisms of toxicity  

British Library Electronic Table of Contents (United Kingdom)

Summary Although risk assessments are typically conducted on a chemical-by-chemical basis, the 1996 Food Quality Protection Act required the US Environmental Protection Agency to consider cumulative risk of chemicals that act via a common mechanism of toxicity. To this end, we are conducting studies with mixtures of chemicals to elucidate mechanisms of joint action at the systemic level with the goal of providing a framework for assessing the cumulative effects of reproductive toxicants. Previous mixture studies conducted with antiandrogenic chemicals are reviewed briefly and two new studies are described. In all binary mixture studies, rats were dosed during pregnancy with chemicals, singly or in pairs, at dosage levels equivalent to approximately one-half of the ED50 for hypospadias or e...

2010-01-01

29

Nuclear forensics-metrological basis for legal defensibility  

International Nuclear Information System (INIS)

The admissibility of nuclear forensics measurements and opinions derived from them in US Federal and State courts are based on criteria established by the US Supreme Court in the case of Daubert v. Merrell Dow and the 2000 Amendment of Rule 702 of the Federal Rules of Evidence. These criteria are being addressed by new efforts that include the development of certified reference materials (CRMs) to provide the basis for analytical method development, optimization, calibration, validation, quality control, testing, readiness, and declaration of measurement uncertainties. Quality data is crucial for all stages of the program, from R and D, and database development, to actual casework. Weakness at any point in the program can propagate to reduce the confidence of final conclusions. The new certified reference materials will provide the necessary means to demonstrate a high level of metrological rigor for nuclear forensics evidence and will form a foundation for legally ...

2009-12-01

30

Durability of Defense Waste Processing Facility glasses within the Purex range of compositions  

Energy Technology Data Exchange (ETDEWEB)

Processing in the Defense Waste Processing Facility (DWPF) is controlled by constraints on predicted properties of the product glass. One of these properties is chemical durability, which is measured as the response of various glass constituents to the seven-day Product Consistency Test (PCT) [1]. As currently implemented into the DWPF`s Product Composition Control System (PCCS) the response of boron is taken as representative of all of the constituent responses, and control is in terms of the boron response. This response, in normalized units and in log scale, is taken to be a linear function of the glass`s free energy of hydration, {Delta}G. {Delta}G is a parameter which represents the sum of influences on durability of the various glass oxide components. A generalized relationship between these two variables is documented in [2]. This relationship appears to underpredict releases for glasses in the so-called ``Purex`` range of compositions ...

1995-05-01

31

Canadian upstream oil and gas industry fire and explosion incident analysis based on the investigative work of the IRP18 Committee working with the University of Calgary Department of Chemical and Petroleum Engineering. Revision 1  

Energy Technology Data Exchange (ETDEWEB)

This report presented an analysis of incidents gathered by the Canadian upstream oil and gas industry committee in relation to explosive atmospheres in wellbores, vessels, tanks, and piping systems. The aim of the report was to develop industry recommended practices for oil and gas industry fires and explosions. Two accident theory models were used to set out the relationships between hazards, defenses, and losses. Three levels of defenses were identified based on organizational, local workplace, and human factors. An organizational responsibility approach was used to examine the activities of key people with the system. Incidents were analyzed based on an expanded fire triangle used to identify fire and explosion hazards. The study showed that the ignition of hydrocarbons into the air was a factor in nearly 50 per cent of the incidents. A lack of understanding of liquid-hydrocarbon properties was demonstrated in incidents involving oxidized ...

2005-05-15

32

The influence of chemically active gas on the light emission of metallic targets bombarded by positive ions  

International Nuclear Information System (INIS)

The introduction of oxygen in the vicinity of a metallic target surface, bombarded with positive argon ions of twenty kiloelectron-volts, increases the number of sputtered atoms in the excited state. This phenomenon of exaltation, very sensitive in the case of nickel and aluminium, is much less marked in the case of molybdenum. Moreover, the emission of excited particles coming from the beam's ions is not modified. A quantum-mechanical model of a kinetic emission process, which permits the interpretation of the clean metallic target's emission phenomena, seems insufficient to explain all of the results obtained in the presence of oxygen. In this last case one can therfore use a thermodynamic model in which excited metallic particles can be formed directly by chemical surface reactions of neutralization or reduction. (orig.).

33

Production and remediation of low-sludge, simulated Purex waste glasses, 1: Effects of sludge oxide additions on melter operation  

Energy Technology Data Exchange (ETDEWEB)

Glass produced during the Purex 4 campaigns of the Integrated Defense Waste Processing Facility (DWPF) Melter System (IDMS) and the 774 Research Melter contained a lower fraction of sludge components than targeted by the Product Composition Control System (PCCS). Purex 4 glass was more durable than the benchmark (EA) glass, but less durable than most simulated SRS high-level waste glasses. Also, Purex 4 glass was considerably less durable than predicted by the algorithm which will be used to control production of DWPF glass. A melter run was performed using the 774 Research Melter to determine if the initial PCCS target composition determined for Purex 4 would produce acceptable glass whose durability could be accurately modeled by Hydration Thermodynamics. Reagent grade oxides and carbonates were added to Purex 4 melter feed stock to simulate a higher sludge loading. Each canister of glass produced was sampled and the ...

1993-07-15

34

Blood gene expression markers to detect and distinguish target organ toxicity  

British Library Electronic Table of Contents (United Kingdom)

The purpose of this study was to investigate whether the expression of specific genes in peripheral blood can be used as surrogate marker(s) to detect and distinguish target organ toxicity induced by chemicals in rats. Rats were intraperitoneally administered a single, acute dose of a well-established hepatotoxic (acetaminophen) or a neurotoxic (methyl parathion) chemical. Administration of acetaminophen (AP) in the rats resulted in hepatotoxicity as evidenced from elevated blood transaminase activities. Similarly, administration of methyl parathion (MP) resulted in neurotoxicity in the rats as evidenced from the inhibition of acetyl cholinesterase activity in their blood. Administration of either chemical also resulted in mild hematotoxicity in the rats. Microarray analysis of the global ...

2010-01-01

35

Year 2000 Computing Issues Related to the Defense Fuels ...  

Science.gov (United States)

... manual efforts by DESC and the Defense Finance and Accounting Service would ... in serious mission and financial impacts on DLA, DESC, the ...

1999-05-17

36

USGS National Wetlands Research Center: Press Release  

Science.gov (United States)

Challenges of robotic cars, sponsored by the Defense Advanced Research Projects Agency (DARPA) of the U.S. Defense Department. Carroll Cordes, recently retired USGS branch chief,...

2011-08-27

37

From National Defense Stockpile (NDS) to Strategic Materials ...  

Science.gov (United States)

... Title : From National Defense Stockpile (NDS) to Strategic Materials Security Program (SMSP): Evidence and Analytic Support. Volume 1. ...

2010-05-01

38

Defense.gov News Article: DARPA Effort Speeds Biothreat ...  

Science.gov (United States)

... H1N1 a pandemic virus in June 2009, the Defense Advanced Research Projects Agency had a plan to address the crisis. The DARPA effort, called ...

39

Archive | October 27, 2009 | Armed with Science  

Science.gov (United States)

with Science, Dr. Barbara McQuiston of the Defense Advanced Research Projects Agency (DARPA), spoke about a few interesting ways the Department of Defense is trying to...

2011-08-28

40

Pinellas Plant Environmental Baseline Report  

Energy Technology Data Exchange (ETDEWEB)

The Pinellas Plant has been part of the Department of Energy`s (DOE) nuclear weapons complex since the plant opened in 1957. In March 1995, the DOE sold the Pinellas Plant to the Pinellas County Industry Council (PCIC). DOE has leased back a large portion of the plant site to facilitate transition to alternate use and safe shutdown. The current mission is to achieve a safe transition of the facility from defense production and prepare the site for alternative uses as a community resource for economic development. Toward that effort, the Pinellas Plant Environmental Baseline Report (EBR) discusses the current and past environmental conditions of the plant site. Information for the EBR is obtained from plant records. Historical process and chemical usage information for each area is reviewed during area characterizations.

1997-06-01

41

Differential Performance of a Specialist and Two Generalist Herbivores and Their Parasitoids on Plantago lanceolata  

British Library Electronic Table of Contents (United Kingdom)

The ability to cope with plant defense chemicals differs between specialist and generalist species. In this study, we examined the effects of the concentration of the two main iridoid glycosides (IGs) in Plantago lanceolata, aucubin and catalpol, on the performance of a specialist and two generalist herbivores and their respective endoparasitoids. Development of the specialist herbivore Melitaea cinxia was unaffected by the total leaf IG concentration in its host plant. By contrast, the generalist herbivores Spodoptera exigua and Chrysodeixis chalcites showed delayed larval and pupal development on plant genotypes with high leaf IG concentrations, respectively. This result is in line with the idea that specialist herbivores are better adapted to allelochemicals in host plants on which they...

2011-01-01

42

The production of carrier-free lead-203  

International Nuclear Information System (INIS)

The chemical separation of carrier-free "2"0"3Pb following deuterium bombardment of a "2"0"3Tl target is described. Coprecipitation from strontium sulphate was used to separate the "2"0"3Pb from a solution of the thallium target in sulphuric acid. The SrSO_4 precipitate was filtered, washed and dissolved in hydrochloric acid, from which "2"0"3Pb was again separated by precipitation on sodium chloride from a strongly acid solution. Advantages of the system are discussed and optimum conditions given. (U.K.).

43

Production of carrier-free lead-203  

Energy Technology Data Exchange (ETDEWEB)

The chemical separation of carrier-free /sup 203/Pb following deuterium bombardment of a /sup 203/Tl target is described. Coprecipitation from strontium sulphate was used to separate the /sup 203/Pb from a solution of the thallium target in sulphuric acid. The SrSO/sub 4/ precipitate was filtered, washed and dissolved in hydrochloric acid, from which /sup 203/Pb was again separated by precipitation on sodium chloride from a strongly acid solution. Advantages of the system are discussed and optimum conditions given.

1982-07-01

44

Modification of a gas jet transport system for the supression of heavy-mass fission product homologues  

Energy Technology Data Exchange (ETDEWEB)

The uranium target of a gas jet transport system for fission products has been modified by the addition of an aluminum cover foil. The new modification allows fission fragments of low mass to enter a continuous chemistry system while heavier fragments are stopped in the aluminum. The elimination of the heavier homologues allows development of simpler and faster chemical separation procedures. In addition, since the lighter fragments are slowed down by the cover foil a smaller target chamber can be used. This leads to a reduction in system holdup time.

1987-04-15

45

Modification of a gas jet transport system for the supression of heavy-mass fission product homologues  

International Nuclear Information System (INIS)

The uranium target of a gas jet transport system for fission products has been modified by the addition of an aluminum cover foil. The new modification allows fission fragments of low mass to enter a continuous chemistry system while heavier fragments are stopped in the aluminum. The elimination of the heavier homologues allows development of simpler and faster chemical separation procedures. In addition, since the lighter fragments are slowed down by the cover foil a smaller target chamber can be used. This leads to a reduction in system holdup time. (orig.).

47

From National Defense Stockpile (NDS) to Strategic Materials Security Program (SMSP): Evidence and Analytic Support. Volume 1.  

Science.gov (United States)

In 1987, the U.S. Congress assigned the Secretary of Defense the job of determining requirements for and managing the National Defense Stockpile (NDS) of 'strategic and critical' non-fuel materials (S&CMs). Since then, the Institute for Defense Analyses (...

2010-01-01

49

Cyclotron produced lead-203  

International Nuclear Information System (INIS)

The radioactive isotopes of lead are reviewed with respect to their choice for in vitro tracer studies. The #gamma#-photon energy and absence of particle emission in the decay of "2"0"3Pb makes it particularly suitable for these applications. Reaction yields of "2"0"3Pb using "2"0"3Tl targets and proton, deuteron, "3He and "4He beams are listed. Using the preferred reaction "2"0"3Tl (d, 2n)"2"0"3Pb with a 15 MeV deuteron beam, yields of about 75 #mu#Ci #mu#Ahr"-"1, after chemical separation, are reported. Details of target design and chemical separation are given. (U.K.).

50

Studies on heterogeneous simulated Am targets. Influence of lanthanide oxides  

Energy Technology Data Exchange (ETDEWEB)

Targets for heterogeneous transmutation of americium are composed of a support material, the inert matrix and of an americium oxide compound: AmO{sub 2-x} or Am{sub 2}O{sub 3}. In parallel to the studies using americium, simulated compounds of americium oxide, chosen amongst lanthanide oxides, are used. The selection of these compounds is based on theoretical, physical and crystallochemical considerations. In order to assess the influence of impurities composed of lanthanide oxides, resulting from the separation process, on the physical and chemical properties of such a target, synthesis of oxide powders containing impurities associated with the simulated americium oxide, characterizations, crystallographic studies and sodium compatibility tests have been performed. (author)

1997-12-31

51

Measurement of K x-ray intensity ratio of tin, gadolinium and dysprosium  

International Nuclear Information System (INIS)

Full text: Measurement of K_#beta# to K_#alpha# x-ray intensity ratios are important not only in the field of atomic physics, radiation physics and medical physics, but also to test the validity of assumptions made in the theoretical prediction. The intensity ratios can also give information on the effect of physical and chemical environment of the element in the compound. Many investigators have adopted a single and double reflection geometries to measure the K_#beta# to K_#alpha# x ray intensity ratios to understand the effect of physical and chemical environment on x-ray fluorescence. The targets are excited by a radioactive source of having activity of the order 100 MBq. in order to carry out accurate measurement K_#beta# to K_#alpha# x-ray intensity ratios, we have develop 2#pi# geometrical configuration method : placing a target right on the surface of the detector facing the ...

2003-11-01

52

Ecotoxicology of Explosives  

Energy Technology Data Exchange (ETDEWEB)

Managing sites contaminated with munitions constituents is an international challenge. Although the choice of approach and the use of Ecological Risk Assessment (ERA) tools may vary from country to country, the assurance of quality and the direction of ecotoxicological research are universally recognized as shared concerns. Drawing on a multidisciplinary team of contributors, 'Ecotoxicology of Explosives' provides comprehensive and critical reviews available to date on fate, transport, and effects of explosives. The book delineates the state of the science of the ecotoxicology of explosives, past, present, and recently developed. It reviews the accessible fate and ecotoxicological data for energetic materials (EMs) and the methods for their development. The chapters characterize the fate of explosives in the environment, then provide information on their ecological effects in key environmental media, including aquatic, sedimentary, and terrestrial habitats. The book ...

2009-04-01

53

Conversion of a plasma enhanced chemical vapor deposited silicon-carbon-nitride thin film at ultra-low temperature by oxygen plasma  

Energy Technology Data Exchange (ETDEWEB)

In this work we present an ultra-low temperature method for the oxidation of an amorphous silicon-carbide-nitride (SiCN) material. The SiCN is deposited on silicon substrates by plasma enhanced chemical vapor deposition using CH{sub 4}, SiH{sub 4}, and N{sub 2} chemistry. The physical and chemical properties are characterized for the as-deposited SiCN and post-oxidized films are discussed. The SiCN film is exposed to oxygen plasma, where it undergoes a chemical transformation into a binary SiO{sub 2} material system. A 1.7 nm/min oxidation rate is typical for this process and compares favorably to oxidation methods utilizing much higher temperatures. The substrate temperature remains extremely low throughout the oxidation process, T{sub s} < 200 deg. C. Changes in film stress, optical constants, film thickness, surface roughness, and film density are measured. Chemical analysis by X-ray ...

2008-01-30

54

Requirements for modeling and simulation of space RSTA assets  

Science.gov (United States)

The Department of Defense (DoD) has long depended on military support functions enabled by space reconnaissance, surveillance, and target acquisition (RSTA) assets. Future generation satellite capabilities will further push technologies in space - if the right technologies are deployed in the right numbers and with the right payloads. Modeling and simulation play major parts in developing and deploying such assets: 1) system and operational requirements determination, and 2) assessment of military utility of such assets. Each area is critical in a system"s life cycle. Requirements determination cuts across the issues of doctrine, organizations, training, materiel, leader development, personnel, and facilities (DOTMLPF). Military utility assessments are necessary to explore and quantify the military worth/benefit of space RSTA assets to operational commanders. Each of these areas requires relevant modeling/simulation tools which span the ...

2004-09-01

55

Efficacy of three commercially available ballast water biocides against vegetative microalgae, dinoflagellate cysts and bacteria  

British Library Electronic Table of Contents (United Kingdom)

One proposed solution to the problem of ballast-mediated aquatic invasions involves chemically treating ballast water to kill key target organisms. Here, we examine the efficacy of three commercially available ballast water biocides using vegetative microalgae, dinoflagellate resting cysts and bacteria as test organisms. Chemicals tested were the ballast water biocides SeaKleen and Peraclean Ocean, and the chlorine dioxide biocide Vibrex. Results demonstrate that the applicability of each of the three chemical biocides as a routine ballast water treatment is limited by factors such as cost, biological effectiveness and possible residual toxicity of the discharged ballast water (assessed on the basis of impact on motility of vegetative marine microalgae). Of the three biocides tested, Perac...

2007-01-01

56

Cell-mediated mutagenesis and cell transformation of mammalian cells by chemical carcinogens. [Rats, hamsters  

Science.gov (United States)

We have developed a cell-mediated mutagenesis assay in which cells with the appropriate markers for mutagenesis are co-cultivated with either lethally irradiated rodent embryonic cells that can metabolize carcinogenic hydrocarbons or with primary rat liver cells that can metabolize chemicals carcinogenic to the liver. During co-cultivation, the reactive metabolites of the procarcinogen appear to be transmitted to the mutable cells and induce mutations in them. Assays of this type make it possible to demonstrate a relationship between carcinogenic potency of the chemicals and their ability to induce mutations in mammalian cells. In addition, by simultaneously comparing the frequencies of transformation and mutation induced in normal diploid hamster cells by benzo(a)pyrene (BP) and one of its metabolites, it is possible to estimate the genetic target size for cell transformation in vitro.

1977-01-01

57

Preparation of a "6"2Zn-"6"2Cu generator and of "6"1Cu following alpha particle irradiation of a nickel target  

International Nuclear Information System (INIS)

The "6"2Zn-"6"2Cu generator system is one of the few which yield a pure positron emitting daughter. The authors have developed a method for the preparation of this generator system following 32 MeV #alpha# particle bombardment of nickel targets. The chemical processing involves two stages: first a hydrous zirconium oxide column is used at pH 4-5 to separate the zinc and copper activities produced in the target nickel, and secondly, a conventional anion exchange column is used to retain the "6"2Zn and remove all copper activities in 2M HCl. This column serves as the "6"2Cu generator which will yield pure "6"2Cu repeatedly, free from "6"2Zn and other impurities, in a mixture of HCl and NaCl. A method is outlined also to obtain a solution of "6"2Zn using the hydrous zirconium oxide (HZO) column. "6"1Cu can be prepared as a by-product in the above procedure, but a method for the preparation of "6"1Cu alone using an 18 MeV ...

58

Mass Production of 64Cu with 64Ni(p,n)64Cu Nuclear Reaction and Target Material Recycling  

International Nuclear Information System (INIS)

64Cu (T1/2=12.7h, ?- decay: 40%, ?+ decay: 19%, E.C. decay: 41%) is one of the most useful radioisotope in the nuclear medicine due to its multiple decay mode and the intermediate half-life. Several nuclear reaction, i.e., 64Ni(p,n)64Cu, 68Zn(p,?n)64Cu and 64Ni(d,2n)64Cu have been investigated for production. The highest could be obtained with proton irradiation on the enriched 64Ni target. For mass and routine production, the 64Ni target fabrication using electroplating, the reliable chemical separation of 64Cu from the irradiated 64Ni target and the effective recovery process for the recycling of very expensive enriched material ($20,000/g) and so forth are absolutely necessary to be established. In this work, we report our mass production method of 64Cu with 64Ni and Cyclone-30 accelerator

2009-05-01

59

Fifty years of federal radioactive waste management: Policies and practices  

Energy Technology Data Exchange (ETDEWEB)

This report provides a chronological history of policies and practices relating to the management of radioactive waste for which the US Atomic Energy Commission and its successor agencies, the Energy Research and Development Administration and the Department of Energy, have been responsible since the enactment of the Atomic Energy Act in 1946. The defense programs and capabilities that the Commission inherited in 1947 are briefly described. The Commission undertook a dramatic expansion nationwide of its physical facilities and program capabilities over the five years beginning in 1947. While the nuclear defense activities continued to be a major portion of the Atomic Energy Commission`s program, there was added in 1955 the Atoms for Peace program that spawned a multiplicity of peaceful use applications for nuclear energy, e.g., the civilian nuclear power program and its associated nuclear fuel cycle; a variety of industrial applications; and ...

1997-04-01

60

An Arabidopsis thaliana methyltransferase Capable of Methylating Farnesoic Acid  

Energy Technology Data Exchange (ETDEWEB)

We previously reported the identification of a new family of plant methyltransferases (MTs), named the SABATH family, that use S-adenosyl-l-methionine (SAM) to methylate a carboxyl moiety or a nitrogen-containing functional group on a diverse array of plant compounds. The Arabidopsis genome alone contains 24 distinct SABATH genes. To identify the catalytic specificities of members of this protein family in Arabidopsis, we screened recombinantly expressed and purified enzymes with a large number of potential substrates. Here, we report that the Arabidopsis thaliana gene At3g44860 encodes a protein with high catalytic specificity towards farnesoic acid (FA). Under steady-state conditions, this farnesoic acid carboxyl methyltransferase (FAMT) exhibits K{sub M} values of 41 and 71 {mu}M for FA and SAM, respectively. A three-dimensional model of FAMT constructed based upon similarity to the experimentally determined structure of Clarkia breweri salicylic acid methyltransferase (SAMT) ...

2006-01-01

61

Simultaneous production of "2"8Mg and "4"7Ca by high-energy heavy-ion irradiation for applications in biology  

International Nuclear Information System (INIS)

With the aim of preparing carrier-free "2"8Mg and "4"7Ca simultaneously, Ti, V and Fe targets were examined by irradiating with high-energy ions of "1"2C, "1"4N and "1"6O accelerated by the RIKEN ring cyclotron. Among the targets, V gave the highest cross section for the formation of both "2"8Mg and "4"7Ca irrespective of the kind of beams. The cross section for the formation of "2"8Mg by the reactions of Ti, V and Fe targets with ion beams increased in the order of "1"2C<"1"6O<"1"4N. On the other hand, the three beams exhibited almost the same cross sections for the formation of "4"7Ca by the reaction of a given target. Titanium and V were selected as prospective targets and "1"4N as a suitable beam for the production of "2"8Mg and "4"7Ca. Chemical separation procedures of the radiotracers in carrier- and salt-free states have been established by using ...

62

Role of accelerator mass spectrometry in biological dosimetry  

International Nuclear Information System (INIS)

Understanding risks from exposures to carcinogens and other chemicals depends upon measurement of their dose to target tissues and their reactivity with critical macromolecules. The authors have used AMS detection of radio-isotopes to assess doses and reactivities at low, environmentally relevant doses. Several biomedical investigations show the effectiveness of quantification of biologically important events at extremely high sensitivity with AMS. Specifically, they have measured the addition of environmental carcinogens such as 2-amino-3,8-dimethylimidazo[4,5-f]-quinoaxaline (MelQx), a chemical found in cooked food, to DNA at concentrations relevant to human exposure. Other low level detection problems in biology, such as immunoassay assessment of small environmental chemicals, is being developed with attomole sensitivity. AMS also aids the assessment of genotoxic risks from ...

1992-04-05

63

Criminal Prohibitions on the Publication of Classified Defense Information. Updated October 18, 2010.  

Science.gov (United States)

The recent online publication of classified defense documents by the organization WikiLeaks and subsequent reporting by the New York Times and other news media have focused attention on whether such publication violates U.S. criminal law. The Attorney Gen...

2010-01-01

64

Criminal Prohibitions on the Publication of Classified Defense Information. Updated December 6, 2010.  

Science.gov (United States)

The recent online publication of classified defense documents and diplomatic cables by the organization WikiLeaks and subsequent reporting by the New York Times and other news media have focused attention on whether such publication violates U.S. criminal...

2010-01-01

65

The review of radioactive waste management in the world  

International Nuclear Information System (INIS)

Radioactive waste is generally classified on the basis of how much radiation and the type of radiation it emits as well as the length of time over which it will continue to emit radiation. Many activities dealing with radioactive materials produce nuclear wastes, including civilian nuclear power programs (nuclear Power plant operations and nuclear fuel-cycle activities), defense nuclear programs (nuclear weapons production, naval nuclear reactor programs, and related R and D), and industrial and institutional activities (scientific research, medical operations, and other industrial uses of Radioisotopic sources or Radio chemicals). To minimize the potential adverse health and environment impacts to people and other systems including of animals, plant and etc, during the entire lifetime of the radionuclides involved, nuclear waste must be carefully and properly managed. The scope of nuclear - waste management encompasses generation, processing ...

66

The frontal weapon of the termite Armitermes euamignathus Silvestri (Isoptera, Termitidae, Nasutitermitinae)  

Scientific Electronic Library Online (English)

Abstract in english Frontal weapon is the term used to designate the apparatus consisting of frontal gland and associated structures that participate in the chemical defense of termite soldiers. The ultra structure of the frontal gland and the scanning microscopy of the soldier head was investigated in the termite Amiitermes euamignathus Silvestri, 1901.Campaniform sensilla was not observed but there were 80 to100 sensory bristles around the frontal pore. The glandular epithelium shows only (more) class 1 cells according 10 the classification of NOIROT & QUENNEDEY (1974, 1991). The glandular cells are characterized by apical microvilli, a basal labyrinth and a large quantity of smooth endoplasmic reticulum which forms dense zones throughout the cytoplasm. The secretion is concentrated mainly in the basal pole of the cell and consists of large lipid droplets. The secretory epithelium is covered by a thick apical cuticle composed of a thin ...

2001-06-01

67

Why Strategy is Difficult  

Science.gov (United States)

... In the Arabian Gulf region, environmental security efforts complement USCENTCOM's Cooperative Defense Initiative (CDI) activities, and offer a ...

2011-05-13

68

Transformational Satellite (TSAT) Communications Systems. ...  

Science.gov (United States)

... The seven existing space/airborne programs are the Defense Satellite Com- munications System (DSCS), Milstar, communications re- lay ...

2007-07-01

69

The Manning Requirements for the Navy's Forward ...  

Science.gov (United States)

... Task Force Commander's Handbook for Domestic ... and Radiological (CBR) Defense Requirements Supporting ... DC: Department of Navy, May 1996 ...

2011-05-13

70

Federal Catalog System Policy Manual  

Science.gov (United States)

... The Defense Logistics Agency (DLA) is responsible for management and administration of the ... 1, Accounting and Finance Manual, and sa N ...

1975-03-01

71

Defense Science Board 2006 Summer Study of Information ...  

Science.gov (United States)

... Those communications and information management capabilities required in the battlefield should be part of the weapon system. ...

2007-04-01

72

Defense Alternatives for the Small Nations  

Science.gov (United States)

... EC) in Western Europe and the Gulf Cooperation Council of the Arab States (GCC) in the Arabian Gulf region. Others. but ...

1989-05-01

73

DEFENSE METALS INFORMATION CENTER SELECTED ...  

Science.gov (United States)

... The total hemispherical emittance rig has been returned to service and the quality of temperature measurement has been investigated. ...

1963-11-01

74

Concerning a Comprehensive Nuclear Test Ban  

Science.gov (United States)

... US Congress, Joint Committee on Atomic Energy, Development, Use, and Control ofNuclear Energy for the Common Defense and Security and for ...

2011-05-14

75

A Profile of Defense Manufacturing Costs and Enabling ...  

Science.gov (United States)

... Casting Explosive forming Forging Electrohydraulic forming Extruding Magnetic forming Rolling Electroforming Drawing Powdered metal forming ...

1992-01-01

76

Progress on polarized target materials with pure carbon background  

Science.gov (United States)

A previous note reviewed methods for the paramagnetic doping of materials for spin-polarized solid targets and some of the history of attempts to apply those methods to hydrocarbons. Since the earlier work on hydrocarbons had yielded, at best, rather mediocre results, that note also speculated on some ways to extend and, possibly, to improve upon the earlier work. The sharpest focus was on the light (number of carbons less than six) alkanes, since these are the hydrocarbons that have the highest hydrogen contents ([approx gt] 17wt %) and therefore require the least degree of polarization to be interesting. This present note summarizes the subsequent work done, to date, exploring some of the issues related to the chemical doping method. The main areas of progress have been in the literature search, experimental results on glass formation by alkanes, and a polarizing test of a prototype'' hydrocarbon.

1993-03-24

77

Progress on polarized target materials with pure carbon background  

Energy Technology Data Exchange (ETDEWEB)

A previous note reviewed methods for the paramagnetic doping of materials for spin-polarized solid targets and some of the history of attempts to apply those methods to hydrocarbons. Since the earlier work on hydrocarbons had yielded, at best, rather mediocre results, that note also speculated on some ways to extend and, possibly, to improve upon the earlier work. The sharpest focus was on the light (number of carbons less than six) alkanes, since these are the hydrocarbons that have the highest hydrogen contents ([approx gt] 17wt %) and therefore require the least degree of polarization to be interesting. This present note summarizes the subsequent work done, to date, exploring some of the issues related to the chemical doping method. The main areas of progress have been in the literature search, experimental results on glass formation by alkanes, and a polarizing test of a prototype'' hydrocarbon.

1993-03-24

78

Progress on polarized target materials with pure carbon background  

Energy Technology Data Exchange (ETDEWEB)

A previous note reviewed methods for the paramagnetic doping of materials for spin-polarized solid targets and some of the history of attempts to apply those methods to hydrocarbons. Since the earlier work on hydrocarbons had yielded, at best, rather mediocre results, that note also speculated on some ways to extend and, possibly, to improve upon the earlier work. The sharpest focus was on the light (number of carbons less than six) alkanes, since these are the hydrocarbons that have the highest hydrogen contents ({approx_gt} 17wt %) and therefore require the least degree of polarization to be interesting. This present note summarizes the subsequent work done, to date, exploring some of the issues related to the chemical doping method. The main areas of progress have been in the literature search, experimental results on glass formation by alkanes, and a polarizing test of a ``prototype`` hydrocarbon.

1993-03-24

79

Production of plutonium, yttrium and strontium tracers for using in environmental research  

International Nuclear Information System (INIS)

Summary of cyclotron production methods of "2"3"7Pu (45,2 d), "8"8Y (106,65 d) and "8"5Sr (64,84 d) tracers via nuclear reactions with protons and alphas on "2"3"5U, "8"8Sr and "8"5Rb targets in wide energy range is given. Chemical methods of separation and purification of the tracers from the irradiated uranium, strontium and rubidium targets are described. The tracers were used for determination of Pu (239-240), Sr-90 and Am-241 in the samples (soil, plants, underground waters) from Semipalatinsk Test Site. Obtained results are discussed.

2001-12-12

80

Ion-induced M X-ray emission from heavy lanthanides  

International Nuclear Information System (INIS)

Thick targets of several heavy lanthanide (Ho-Lu) compounds were bombarded by protons and "3He ions of 3 MeV/amu, and M_#alpha# and M_#beta# X-rays were measured with a crystal spectrometer. Ionization probabilities of the N-shell for zero impact parameter were obtained from the X-ray intensity ratio for proton and "3He ion impacts. A shell dependence of the ionization probability was found in a scaling plot. X-ray spectra of lanthanide compounds were compared and no chemical effect was observed. This result is considered to be due to the fact that the main component of M_#alpha# and M_#beta# lines is for radiative transition after the refilling of the 4f orbit (3d"-"14f"n"+"1 #-># 4f"n) where n denotes the number of 4f electrons of the target atom before ionization. (orig.).

1987-12-01

81

Inhibition of Metabolism of Diethylene Glycol Prevents Target Organ Toxicity in Rats  

British Library Electronic Table of Contents (United Kingdom)

Diethylene glycol (DEG) is an industrial chemical, the misuse of which has led to numerous epidemic poisonings worldwide. The mechanism of its toxicity has not been defined as to the precise relationship between the metabolism of DEG and target organ toxicity. The purpose of this study was to investigate the mechanism for the acute toxicity of DEG, and the effect of the alcohol dehydrogenase inhibitor 4-methylpyrazole (fomepizole), by determining the relationship between accumulation of DEG or its metabolites and the resulting kidney and liver toxicity. Rats were treated by oral gavage with water, 2 g/kg DEG (low dose), 10 g/kg DEG (high dose), or 10 g/kg DEG + fomepizole, and blood and urine were collected over 48 h. Rats treated with high-dose DEG had metabolic acidosis, increased BUN an...

2010-01-01

82

Waste treatment process for removal of contaminants from aqueous, mixed-waste solutions using sequential chemical treatment and crossflow microfiltration, followed by dewatering  

Energy Technology Data Exchange (ETDEWEB)

It is an object of the claimed invention to combine chemical treatment with microfiltration process to treat groundwater, leachate from contaminated soil washing, surface and run-off waters contaminated with toxic metals, radionuclides and trace amounts of organics from variety of sources. The process can also be used to treat effluents from industrial processes such as discharges associated with smelting, mining and refining operations. Influent contaminants amenable to treatment are from a few mg/L to hundreds of mg/L. By selecting appropriate precipitation, ion exchange and adsorption agents and conditions, efficiencies greater than 99.9 percent can be achieved for removal of contaminants. The filtered water for discharge can be targeted with either an order of magnitude greater or lower than contaminant levels for drinking water.

1992-12-31

83

Coupled mechanical and chemical processes in engineered geothermal reservoirs with dynamic permeability  

British Library Electronic Table of Contents (United Kingdom)

A model is developed to represent mechanical strain, stress-enhanced dissolution, and shear dilation as innately hysteretic and interlinked processes in rough contacting fractures. The model is incorporated into a numerical simulator designed to examine permeability change and thermal exchange in chemically active and deformable fractured reservoirs. A candidate engineered geothermal reservoir system (EGS) is targeted. The mechanistic model is able to distinguish differences between the evolution of fluid transmission characteristics of (1) small scale, closely spaced fractures, and (2) large-scale, more widely spaced fractures. Alternate realizations of fracture frequency and scale, exhibiting identical initial bulk permeability, lead to significantly different conclusions regarding perme...

2010-01-01

84

Waste treatment process for removal of contaminants from aqueous, mixed-waste solutions using sequential chemical treatment and crossflow microfiltration, followed by dewatering  

Energy Technology Data Exchange (ETDEWEB)

In processes of this invention aqueous waste solutions containing a variety of mixed waste contaminants are treated to remove the contaminants by a sequential addition of chemicals and adsorption/ion exchange powdered materials to remove the contaminants including lead, cadmium, uranium, cesium-137, strontium-85/90, trichloroethylene and benzene, and impurities including iron and calcium. Staged conditioning of the waste solution produces a polydisperse system of size enlarged complexes of the contaminants in three distinct configurations: water-soluble metal complexes, insoluble metal precipitation complexes, and contaminant-bearing particles of ion exchange and adsorbent materials. The volume of the waste is reduced by separation of the polydisperse system by cross-flow microfiltration, followed by low-temperature evaporation and/or filter pressing. The water produced as filtrate is discharged if it meets a specified target water quality, or ...

1994-01-01

85

Waste treatment process for removal of contaminants from aqueous, mixed-waste solutions using sequential chemical treatment and crossflow microfiltration, followed by dewatering  

Energy Technology Data Exchange (ETDEWEB)

In processes of this invention aqueous waste solutions containing a variety of mixed waste contaminants are treated to remove the contaminants by a sequential addition of chemicals and adsorption/ion exchange powdered materials to remove the contaminants including lead, cadmium, uranium, cesium-137, strontium-85/90, trichloroethylene and benzene, and impurities including iron and calcium. Staged conditioning of the waste solution produces a polydisperse system of size enlarged complexes of the contaminants in three distinct configurations: water-soluble metal complexes, insoluble metal precipitation complexes, and contaminant-bearing particles of ion exchange and adsorbent materials. The volume of the waste is reduced by separation of the polydisperse system by cross-flow microfiltration, followed by low-temperature evaporation and/or filter pressing. The water produced as filtrate is discharged if it meets a specified target water quality, or ...

1994-11-22

86

Bifurcation and complex dynamics of a two-prey two-predator system concerning periodic biological and chemical control  

Energy Technology Data Exchange (ETDEWEB)

In this paper, we investigate the dynamic behaviors of a two-prey two-predator system with impulsive effect concerning biological and chemical control strategy-periodic releasing natural enemies and spraying pesticide at different fixed time. By applying the Floquet theory of linear periodic impulsive equation and small amplitude perturbation method, we prove that there exists a globally asymptotically stable two-prey-eradication periodic solution when the impulsive period is less than some critical value. The conditions for the permanence of the system are given, and meanwhile the conditions for the extinction of one of the two prey species and permanence of the remaining three species are given. Our results suggest a new approach in pest control. The target pest population can be driven to extinction and the non-target pest can be permanent by choosing impulsive period. With the increasing of the predation rate for the ...

2008-07-15

87

Quality Management for Neutron Transmutation Doping of Silicon Ingot in HANARO  

Energy Technology Data Exchange (ETDEWEB)

By using this doping method, silicon semiconductors with extremely uniform dopant distributions can be produced, and this is the dominant advantage of NTD compared with a conventional chemical doping. Good uniformity of a dopant concentration is usually required for high power applications such as thyristor (SCR), IGBT, IGCT and GTO and for special sensors. Achieving an accurate neutron fluence corresponding to a target resistivity as well as a uniform irradiation is the prime target of a neutron irradiation for NTD. Generally, in order to reach an accurate neutron fluence, a real time neutron flux is monitored by a neutron detector such as a Self-powered Neutron Detector(SPND). And, after an irradiation, the total irradiation fluence is confirmed by measuring the absolute activity of a neutron activation sample that has been irradiated with a silicon ingot, and thus the SPND can be properly calibrated. Excellent ...

2007-10-15

88

Emission factors of polybrominated diphenyl ethers (PBDEs) from plastics processing and recycling facilities  

Energy Technology Data Exchange (ETDEWEB)

With regard to polybrominated diphenyl ether (PBDE), there is few scientific knowledge on the emission patterns into the environment and exposure pathways to humans, and basic information is insufficient to consider what measures effective are. For the purpose of promoting risk reduction of target substances more effectively and efficiently, it is desirable to comprehend accurately the causal chain from the target substances utilization to the risk intake, and to evaluate the measures covering the whole applications of target substances. As the existing researches on the PBDE emission inventory, there are EU risk assessment report (European Chemical Bureau 2000, 2002, 2003), Danish EPA (1999), Palm et al.(2002) and Alcock et al. (2003). In addition, emissions of DecaBDE are published in TRI (Toxic Release Inventory) of US EPA. However, the primary information of the previous inventories is often the ...

2004-09-15

89

Nitric Oxide Signaling as a Common Target of Organohalogens and Other Neuroendocrine Disruptors  

British Library Electronic Table of Contents (United Kingdom)

Organohalogen compounds such as polychlorinated biphenyls (PCB) and polybrominated diphenyl ethers (PBDE) are global environmental pollutants and highly persistent, bioaccumulative chemicals that produce adverse effects in humans and wildlife. Because of the widespread use of these organohalogens in household items and consumer products, indoor contamination is a significant source of human exposure, especially for children. One significant concern with regard to health effects associated with exposure to organohalogens is endocrine disruption. Toxicological studies on organohalogen pollutants primarily focused on sex steroid and thyroid hormone actions, and findings have largely shaped the way one envisions their disruptive effects occurring. Organohalogens exert additional effects on oth...

2011-01-01

90

In vivo magnetic resonance techniques and drug discovery  

International Nuclear Information System (INIS)

The long and resource intensive process of drug discovery and development is confronted with the basic challenge of providing effective and safe therapies at reasonably low costs. The better the mechanism of a disease is known, the higher the probability to find an appropriate therapy. Also, the better and earlier a disease can be diagnosed and characterized, the higher the chance to be able to interfere in this process with a chemical entity. This reasoning sets the framework for the use of imaging in drug discovery. We discuss the relevance of magnetic resonance imaging and spectroscopy to derive anatomical, functional, metabolic and target-related information in the context of pharmacological research in vivo. (author)

2006-03-01

91

Co-product extraction studies on N-reactor PT-57 target materials  

International Nuclear Information System (INIS)

Single pellets (of approximately 70 g each) of irradiated lithium aluminate target from N-Reactor test PT-57 were used in a series of experiments to determine the extent to which the product tritium can be recovered by (a) vacuum outgassing of the target (thermal extraction-TX) and (b) in-vacuo chemical dissolution of the target in molten sodium tetraborate (flux extraction-FX). Five TX runs and seven FX runs were made. Thirty-five percent of the tritium was recovered in a form non-condensable at -196"0C. The remainder was recovered in a condensable form (as T_2O, HTO, etc.). Post-extraction analysis of the melt from the seven flux extractions showed that a maximum of 2 percent of the original amount of tritium remained and that target dissolution was essentially complete in 12 hours. Flux extraction of two pellets which had been subjected to thermal extraction showed less than 0.4 ...

92

Activation analysis of trace elements in titanium-molybdate target used for pre-formed TiMo gel based "9"9"mTc generator production and radionuclidic impurity of "9"9"mTc pertechnetate eluate  

International Nuclear Information System (INIS)

A gel-type "9"9Mo-"9"9"mTc generator using Titanium-Molybdate target (TiMo-target) as column packing was developed in Radioisotope Department, the Dalat Nuclear Research Institute [1]. The concentration of trace elements in TiMo-target and radionuclidic purity in "9"9"mTc solution eluted from this type of generator were studied for quality control purpose. The monostandard method in neutron activation analysis has been applied to determine the concentration of trace impurities in titanium-molybdate target. For neutron activation analysis, TiMo samples were irradiated in the different channels of nuclear reactor IVV-9 at a neutron flux of maximum 2.1 x 10"1"3 n.cm"-"2s"-"1. The following chemical element impurities were determined: Na, W, Co, Fe, Zn, Ag, Sb and Cr. The gamma ray emitted nuclides found in "9"9"mTc solution eluted from our "9"9"mTc generator were the following: "6"5Zn, ...

2004-06-01

94

Constraints on target chamber first wall and target designs that will enable NIF debris shields to survive  

CERN Document Server

Constraints on target chamber first wall and target designs that will enable NIF debris shields to survive

1999-01-01

95

Nanocrystal conversion chemistry: A unified and materials-general strategy for the template-based synthesis of nanocrystalline solids  

International Nuclear Information System (INIS)

The concept of nanocrystal conversion chemistry, which involves the use of pre-formed nanoparticles as templates for chemical transformation into derivative solids, has emerged as a powerful approach for designing the synthesis of complex nanocrystalline solids. The general strategy exploits established synthetic capabilities in simple nanocrystal systems and uses these nanocrystals as templates that help to define the composition, crystal structure, and morphology of product nanocrystals. This article highlights key examples of 'conversion chemistry' approaches to the synthesis of nanocrystalline solids using a variety of techniques, including galvanic replacement, diffusion, oxidation, and ion exchange. The discussion is organized according to classes of solids, highlighting the diverse target systems that are accessible using similar chemical concepts: metals, oxides, chalcogenides, phosphides, alloys, intermetallic ...

2008-07-01

96

Chemistry of transuranium elements and compounds  

International Nuclear Information System (INIS)

Studies are made in this program to enhance our understanding of the role of 5f electrons in chemical bonding. Most of our studies on the macroscopic scale emphasize certain isotopes available from the National Transplutonium Production Program centered at HFIR/TRU -namely, _9_6"2"4"8Cm, _9_7"2"4"9Bk, _9_8"2"4"9Cf, _9_9"2"5"3Es, and _9_9"2"5"4Es. Particular classes of compounds, such as hydrides, chalcogenides, and pnictides are often selected for study on the basis of their utility in bringing out significant chemical differences between the lanthanides and the actinides. High temperature/high pressure experiments on actinide metals and compounds reveal characteristics about the degree of 5f electron localization as a function of atomic number in the series. Magnetic properties of metals and compounds are investigated using ultra-sensitive methods and hydration numbers of ions in solution are investigated by neutron scattering at HFIR. As a ...

1986-05-01

97

Renovation of air-conditioning at La Defense; Renovation de la climatisation a La Defense  

Energy Technology Data Exchange (ETDEWEB)

Twenty years after its building, the tertiary sector of La Defense district near Paris has been rehabilitated. The main reason is not only the age and wear of materials but the heating costs, the fire protection regulations, the search for a better air quality and air renewing with less dusts, smells and noise and a controlled moisture. This paper describes first the original installation of the Monge CB 6 office building and then the renovated installation: the central hot and cold air-treatment plant, the variable flow ventilation system, the air extraction and supply system threw the roofs and the pressure and thermal regulation of the installation. (J.S.)

1997-05-01

98

Defense remote-handled transuranic waste implementation plan: Transuranic Waste Program System Integration Office  

Energy Technology Data Exchange (ETDEWEB)

This document presents a detailed schedule for the implementation of the strategy for managing defense remote-handled (RH) transuranic (TRU) waste. The baseline management strategy was defined in the Defense Remote-Handled Transuranic Waste Cost/Schedule Optimization Study and is summarized in this document. Also included are revised RH TRU waste inventory projections, current site management plans, a list of key decision points and milestones, and a discussion of uncertainties associated with management of RH TRU waste. The plans are summarized in a detailed schedule diagram and in an RH TRU waste work off diagram. 9 refs., 5 figs., 4 tabs.

1988-01-01

99

UnitData 9th Jan  

Science.gov (United States)

... Headquarters Element, Defense Logistics Agency, Support Detachment 3 ... Joint Task Force, Team 6 ... 19th Special Forces Group, Support Element 1 ...

100

The Use of Restricted Air Force Technologies in Joint Federal ...  

Science.gov (United States)

... Concerning Persons and Organizations not Affiliated with the Department of Defense," January 7, 1980 (f) DoD 5240.1-R, "Procedures Governing ...

2011-05-14

101

The Basics of Global Warming - Fight Global Warming - Environmental Defense Fund  

Science.gov (United States)

Information about the greenhouse effect, the role of greenhouse gases in global climate change, levels of greenhouse gases in the atmosphere, and references....

102

Superterrorism and the Military Instrument of Power  

Science.gov (United States)

... Defense. ... 6 Specific restrictions are outlined in US Signals Intelligence Directive (USSID) 18 and DoD Regulation 5240.1-R. 7 House ...

1998-04-01

103

Summaries of Competitive Food Defense Research Reports, 2005  

Science.gov (United States)

... The least effective disinfectant was CTACl, which is a quaternary ammonium surfactant similar to those used in common household disinfectants. ...

104

Strategic Communication: A Department of Defense Approach  

Science.gov (United States)

... development of SC policy within DOD, because it describes the necessary link between DOD ... strategy convolutes USG efforts to develop SC policy. ...

2007-03-28

105

Single Manager for DOD Military Working Dog Program.  

Science.gov (United States)

The Directive establishes a single manager for the Department of Defense Military Working Dog Program, provides policy, prescribes procedures, and assigns responsibilities.

1983-01-01

106

Risk of Peripheral Nerve Disease in Military Workingn> Dogs ...  

Science.gov (United States)

... The study cohort consisted of 2,123 military working dogs that were ... maintained at the Department of Defense Military Working Dog Training Center ...

2011-05-13

107

PolyRAD Space Radiation Shield for Commercial-Off-The  

Science.gov (United States)

Defense satellites, including the next generation GPS and MILSTAR, continue to require TID well above that of most COTS silicon. ...

108

Picornavirus Subversion of the Autophagy Pathway  

UK PubMed Central (United Kingdom)

While autophagy has been shown to act as an anti-viral defense, the Picornaviridae avoid and, in many cases, subvert this pathway to promote their own replication. Evidence indicates...Full Text Available

109

National Response Center Intro Page  

Science.gov (United States)

operations and defense, personnel misconduct (PM), law enforcement (LE), and counterintelligence (CI) investigations.- At any time, the USG may inspect and seize data stored on...

2011-02-28

110

NASA - NASA And DARPA Offer Students Chance To Support ...  

Science.gov (United States)

Jun 20, 2011 ... NASA and the Defense Advanced Research Projects Agency (DARPA) are offering high school students the opportunity to design experiments ...

111

Military Base Closures and Affected Defense Department Civil ...  

Science.gov (United States)

... System (CSRS) and the Federal Employees Retirement System (FERS). ... retirement, thrift savings plan, annual and sick leave, severance pay and ...

2006-03-07

112

Medical Aspects of Sickle Hemoglobin in Military Personnel  

UK PubMed Central (United Kingdom)

The Department of Defense (DOD) will soon issue a directive to test all incoming military personnel for the presence of hemoglobin S. The military testing program for hemoglobin S is an occupational...Full Text Available

1977-01-01

113

Marines Pictures  

Science.gov (United States)

Team 6 Regimental Combat Team 8 Retired Activities Office Safety Division School of Infantry - East School of Infantry - West Second Low Altitude Air Defense Battalion Security...

2011-09-24

114

Logistics Support to Future Unified Commanders  

Science.gov (United States)

... Joint Meritorious Award to DLA," Dimnsions Vol. ... recently the Defense Finance Accounting Services (DFAS ... gmbAt Service SUoDort Field Manual. ...

1993-03-25

115

Lipid Peroxidation and Antioxidant Defense ... - LSDA - Experiment  

Science.gov (United States)

Apr 21, 2011 ... The system of lipid peroxidation reacts regularly to adverse effects and results in enhancement of lipid peroxidation and build-up of LPO ...

116

JPRS Report, Science Technology, Japan.  

Science.gov (United States)

This is Japan Report with Science and Technology. It contains the issues with different topics on biotecnology, defense industry, nuclear engineering, Marine technology, science and technology policy.

1988-01-01

117

Invasive Species Guidebook for Department of Defense ...  

Science.gov (United States)

... Garlic mustard Alliaria petiolata 4 Common (lesser) burdock Arctium minus 6 Giant reed Arundo donax 7 ... Common (lesser) burdock (Arctium minus) ...

2009-06-01

118

Intelligence Oversight Revisited: Does CONUS Base Security ...  

Science.gov (United States)

... Department of Defense (DoD) Directive 5240.1-R. Procedures Governing the Activities of DoD Intelligence Components that Affect United States ...

2001-04-01

119

In Defense of Change Processes  

UK PubMed Central (United Kingdom)

Nativist and constructivist approaches to the study of development share a common emphasis on characterizing beginning and end states in development. This focus has highlighted the question...Full Text Available

2008-01-01

120

Executive Summary-Department of Defense - NASA History Office  

Science.gov (United States)

Sep 5, 1996 ... In Haiti, the military deployed a space support team to advise the task force commander on the effective use of space assets, such as the Milstar ...

121

DefenseLINK News: Third Contingency Exercise Deployment ...  

Science.gov (United States)

... The contingency readiness exercises began in July when a company of soldiers from the Army's 82nd Airborne Division deployed to Haiti for an ...

122

DefenseLINK News: Proposed FMS to Egypt - High Mobility ...  

Science.gov (United States)

... The Government of Egypt has requested a possible sale of 239 High Mobility Multi-purpose Wheeled Vehicles (HMMWV), electronic test set, spare ...

123

DefenseLINK News: General and Flag Officer Assignments  

Science.gov (United States)

... Ward, William E. Brigadier General, Assistant Division Commander (Support), 82nd Airborne Division, Fort Bragg, North Carolina, Chief, Office of ...

124

DefenseLINK News: General Officer Assignments Announced ...  

Science.gov (United States)

... SMITH, EDWIN P. Assistant Division Commander, Commanding General, United States tbd Brigadier General 82nd Airborne Division, Fort Bragg ...

125

DefenseLINK News: General Officer Assignments  

Science.gov (United States)

... Ward, William E. Brigadier General, Assistant Division Commander (Support), 82nd Airborne Division, Fort Bragg, NC, Chief, Office of Military ...

126

DefenseLINK News: Flag and General Officer Assignments  

Science.gov (United States)

... Schmader, John R. Brigadier General, Assistant Division Commander (Operations), 82nd Airborne Division, Ft. Bragg, NC, ...

127

DefenseLINK News: Exercise Fairwinds begins Tuesday ...  

Science.gov (United States)

... This series of contingency readiness exercises began in July when a company of soldiers from the Army's 82nd Airborne Division deployed to Haiti ...

128

DefenseLINK News: DoD Selected Acquisition Report  

Science.gov (United States)

... Change $ -37.0. June 1996 (70 programs*) $ 707,771.1. *Excludes classified costs for the Air Force's MILSTAR program. As of ...

129

DefenseLINK News: Department of Army General Officer ...  

Science.gov (United States)

... Staff for Policy, Supreme Headquarters, Allied Powers ... Command/United States Forces Korea, Korea, Commander, Joint Task Force for Full ...

130

DefenseLINK News: Combined US- Australian Exercise ...  

Science.gov (United States)

... the USCINCPAC staff and the staff of the commander, US Seventh Fleet, as a designated Pacific Command Joint Task Force Headquarters, in crisis ...

131

DefenseLINK News: Brig Gen's for promotion to the grade of ...  

Science.gov (United States)

... Ground, Maryland 21005 Brigadier General Edwin P. Smith Assistant Division Commander 82nd Airborne Division Fort Bragg, North Carolina ...

132

Defense.gov News Article: US Looks at New Ways to Supply ...  

Science.gov (United States)

... that avenue, there would be a disruption in supply, the general ... Transportation Command is responsible not only for supplying warfighters in direct ...

133

Defense.gov News Article: Task Force Prepares for Horn of ...  

Science.gov (United States)

... After the task force deploys, Joint Forces Command interacts ... and what needs tweaking to better prepare future headquarters staffs, Mungus ...

134

Defense.gov News Article: Gates, Mullen Urge Participation in ...  

Science.gov (United States)

... No where on an OER or an NCOER is there a box to be checked ... Chaplains will have a issues with it as far as marriage counseling or other issues ...

135

Defense.gov News Article: Exercise Preps 82nd Airborne ...  

Science.gov (United States)

... Exercise Preps 82nd Airborne Division Staff for Afghanistan Deployment. By Donna Miles American Forces Press Service. WASHINGTON, Nov. ...

136

Defense.gov News Article: Children of Deployed More Likely ...  

Science.gov (United States)

... Gorman said he broke issues down into three categories: anxiety disorders; pediatric behavioral disorders, such as attention deficit disorder; and ...

137

Defense Horizons. Number 18, October 2002. High-Energy ...  

Science.gov (United States)

... assets, particularly against ballistic missiles with weapons of mass ... more con- ventional missile and gun weapon systems. ... Similarly, space-based ...

2002-10-01

138

DOD Cooperation with Civilian Law Enforcement Officials  

Science.gov (United States)

... Concerning Persons and Organizations not Affiliated with the Department of Defense," January 7, 1980 (f) DoD 5240.1-R, "Procedures Governing ...

1986-01-15

139

DNA Hypermethylation Patterns Detected in Serum as a Tool ...  

Science.gov (United States)

... Grant support: National Cancer Institute Center grant CA 16087 and National Cancer Institute grant CA091892, Department of Defense grant ...

2009-09-01

140

Context, Culture, and Connection: Avoiding the Counter ...  

Science.gov (United States)

... Page 25. US Department of Defense, Joint Operation Planning and Execution System, Vol 1, Planning Policies and Procedures (CJCSM 3122.01A). ...

2008-04-23

141

Berkeley Lab News Center: Today at Berkeley Lab  

Science.gov (United States)

who was appointed in July to lead the Defense Advanced Research Projects Agency, or DARPA, made visits last week to UC Berkeley, Stanford, UCLA and the California Institute of...

2011-08-27

142

An Artificial Immune System-Inspired Multiobjective ...  

Science.gov (United States)

... BFS Breadth-First Search BIS Biological Immune System CCNA Cisco-Certified Network Associate CDIS Computer Defense Immune System ...

2007-03-01

143

A shockproof container for the transport and storage of fragile or reactive target foils  

CERN Document Server

A shockproof container for the transport and storage of fragile or reactive target foils

1971-01-01

144

Remediation process technology for ground water  

Energy Technology Data Exchange (ETDEWEB)

The operation of industrial facilities has generally resulted in contamination of the surrounding soils and ground water. A variety of methods have been proposed for the remediation of contaminated sites. This paper presents new process technology that is capable of performing treatment on ground water or soil washing leachates. The process is targeted to treat low levels of radioactivity, organics and heavy metals present in the aqueous solutions, to be easily transported and provide simple operation on-site and provide an effluent that meets the specified discharge quality. The purification process involves sequential chemical treatment and filtration. The paper will describe the development of the technology and review the current progress in its use to remediate contaminated sites at Chalk River. The application of the process technology has demonstrated that the ambitious goal of setting the effluent targets to meet ...

1993-12-31

145

Remediation process technology for ground water  

International Nuclear Information System (INIS)

The operation of industrial facilities has generally resulted in contamination of the surrounding soils and ground water. A variety of methods have been proposed for the remediation of contaminated sites. This paper presents new process technology that is capable of performing treatment on ground water or soil washing leachates. The process is targeted to treat low levels of radioactivity, organics and heavy metals present in the aqueous solutions, to be easily transported and provide simple operation on-site and provide an effluent that meets the specified discharge quality. The purification process involves sequential chemical treatment and filtration. The paper will describe the development of the technology and review the current progress in its use to remediate contaminated sites at Chalk River. The application of the process technology has demonstrated that the ambitious goal of setting the effluent targets to meet ...

1993-09-05

146

Ion-induced M X-ray emission from heavy lanthanides  

Energy Technology Data Exchange (ETDEWEB)

Thick targets of several heavy lanthanide (Ho-Lu) compounds were bombarded by protons and /sup 3/He ions of 3 MeV/amu, and M/sub ..cap alpha../ and M/sub ..beta../ X-rays were measured with a crystal spectrometer. Ionization probabilities of the N-shell for zero impact parameter were obtained from the X-ray intensity ratio for proton and /sup 3/He ion impacts. A shell dependence of the ionization probability was found in a scaling plot. X-ray spectra of lanthanide compounds were compared and no chemical effect was observed. This result is considered to be due to the fact that the main component of M/sub ..cap alpha../ and M/sub ..beta../ lines is for radiative transition after the refilling of the 4f orbit (3d/sup -1/4f/sup n+1/ -> 4f/sup n/) where n denotes the number of 4f electrons of the target atom before ionization.

1987-12-01

147

Guidelines for indoor air hygiene in school buildings  

Energy Technology Data Exchange (ETDEWEB)

The new guidelines for indoor air hygiene in school buildings are intended as a response to current requirements in school practice. The recommendations aim to help to avoid mistakes in modernising school buildings and to provide hygiene-specific support in planning of new school buildings. The guidelines are laid out as follows: (a) In the general section the targets of the guidelines and the target groups are addressed. The current indoor hygiene situation in German schools is described, followed by the parameters with regard to peripheral issues which will not be dealt with further; (b) Part A deals with the hygiene requirements in the practical running of schools. Besides general requirements for maintenance and operation the important issues of cleaning and ventilation are considered, as well as minor building works; (c) Part B provides an overview of important chemical and biological contaminants in schools; (d) Part ...

2008-08-15

148

Natural gas in Lake Erie: a reconnaissance survey of discharges from an offshore drilling rig  

Energy Technology Data Exchange (ETDEWEB)

Field studies were conducted May 28-June 1, 1979, to determine the chemical composition and physical behavior of discharges from an offshore gas drilling rig in the central basin of Lake Erie. The drilling operation was observed for four days, from rig jackup to the circulation of mud through the borehole after drilling had been completed. Resuspension studies using nephelometry, supplemented with chemical analyses, indicated little resuspension of lake bottom materials or release of metals to the water column during rig jack-up. Portions of the turbidity plumes generated during drilling were buoyant. Three surface turbidity plumes were mapped with nephelometry to a point at which particulate concentrations reached background levels in the Lake. Detectable plumes were approx. 400 to 1500 m in length and had maximum widths < 230 m. A chemical survey conducted in the plume during early gas shows indicated that discharged ...

1980-10-01

149

The national nuclear material tracking system. A Korea's countermeasure against nuclear terrorism  

International Nuclear Information System (INIS)

Since nuclear terrorism has been identified as a real threat, the Korean government has earnestly developed elementary technologies and sub-systems for establishing an integrated defensive system against nuclear terrorism, which is based on the concept of defense-in-depth. This paper introduces the gist and implications of the studies that have been conducted in building the national nuclear material tracking system for preventing and intercepting the illicit trafficking and transporting of nuclear material in Korea. (orig.)

2011-07-01

150

Information/records management-defensible budgets for the 21st century  

Energy Technology Data Exchange (ETDEWEB)

This paper provides to the Nuclear Information and Records Management Association (NIRMA) members the skills, knowledge, and information needed to develop performance-based cost estimating. It includes a detailed basis of estimates to represent a work breakdown structure that is technically complete, fully documented, defensible to various external reviews, and validatable.

1995-08-01

151

The Immunity-related GTPase Irgm3 Relieves Endoplasmic Reticulum Stress Response during Coxsackievirus B3 Infection via a PI3K/Akt Dependent Pathway.  

Science.gov (United States)

The IRG protein Irgm3 preserves cell survival during coxsackievirus B3 (CVB3) infection. However, the molecular mechanisms are not clear. Here, we examined the effect of Irgm3 expression on ER stress triggered by pharmacological agents or CVB3 infection. In Tet-On/Irgm3 HeLa cells, Irgm3 expression suppressed either chemical- or CVB3-induced upregulation of glucose-regulated protein78. Further, Irgm3 strongly inhibited the activation of both the PERK and ATF6 pathways of ER stress responses, which further led to the diminished phosphorylation of eIF2?, reduced cleavage/activation of transcription factor SREBP1 and attenuated induction of proapoptotic genes CHOP and GADD34. These data were further supported by experiments using Irgm3 knockout mouse embryonic fibroblasts, in which the ER stress induced by CVB3 was not relieved due to the lack of Irgm3 expression. In addition, the tunicamycin-triggered ER stress promoted the subsequent CVB3 infection. The effect of ...

2011-10-10

152

Status and strategies in radioactive waste management in the Russian Federation  

International Nuclear Information System (INIS)

Full text: There are following general tendencies linking to SNF and radioactive waste management (RWM) in the Russian nuclear industry now. The intention to use the closed nuclear fuel cycle based on power water reactors and fast reactor. The intensification of measures aimed at the solution of 'nuclear legacy' from defenses programs of USSR. The intention to improve the existing national RW management infrastructure in the near years by means of the creation of a centralized national system (including managing corporation responsible for operation of long-storage and disposal facilities of conditioned RW). The main aims radioactive waste management (RWM) in nuclear power plants (NPP) for the next 10-15 years are to equip all NPPs with the necessary set of facilities for conditioning of the stored and currently generated RW with packaging the end-product into containers, to build regional NPPs RW repositories and to introduce evaporator bottoms selective ...

153

The discovery and development of proteomic safety biomarkers for the detection of drug-induced liver toxicity  

British Library Electronic Table of Contents (United Kingdom)

Biomarkers are biometric measurements that provide critical quantitative information about the biological condition of the animal or individual being tested. In drug safety studies, established toxicity biomarkers are used along with other conventional study data to determine dose-limiting organ toxicity, and to define species sensitivity for new chemical entities intended for possible use as human medicines. A continuing goal of drug safety scientists in the pharmaceutical industry is to discover and develop better trans-species biomarkers that can be used to determine target organ toxicities for preclinical species in short-term studies at dose levels that are some multiple of the intended human dose and again later in full development for monitoring clinical trials at lower therapeutic ...

2010-01-01

154

Cost-time management for environmental restoration activities at the Department of Energy`s Idaho National Engineering Laboratory, Idaho Chemical Processing Plant  

Energy Technology Data Exchange (ETDEWEB)

Cost-time management methods have been developed by Westinghouse to examine business applications from a cost-time perspective. The initial application of cost-time management within Westinghouse was targeted at reducing cycle time in the manufacturing sector. As a result of the tremendous success of reduced cycle time in manufacturing, Westinghouse initiated application of the management technique to Environmental Restoration activities at its Government Owned Contractor Operated facilities. The Westinghouse initiative was proposed in support of the Department of Energy`s goals for cost effective Environmental Restoration activities. This paper describes the application of the cost-time method to Environmental Restoration work currently being performed at the Idaho National Engineering Laboratory (INEL) for the Department of Energy (DOE) by Westinghouse Idaho Nuclear Company (WINCO).

1992-05-22

155

Cost-time management for environmental restoration activities at the Department of Energy's Idaho National Engineering Laboratory, Idaho Chemical Processing Plant  

International Nuclear Information System (INIS)

Cost-time management methods have been developed by Westinghouse to examine business applications from a cost-time perspective. The initial application of cost-time management within Westinghouse was targeted at reducing cycle time in the manufacturing sector. As a result of the tremendous success of reduced cycle time in manufacturing, Westinghouse initiated application of the management technique to Environmental Restoration activities at its Government Owned Contractor Operated facilities. The Westinghouse initiative was proposed in support of the Department of Energy's goals for cost effective Environmental Restoration activities. This paper describes the application of the cost-time method to Environmental Restoration work currently being performed at the Idaho National Engineering Laboratory (INEL) for the Department of Energy (DOE) by Westinghouse Idaho Nuclear Company (WINCO).

1992-08-23

156

Achieving success abroad  

Energy Technology Data Exchange (ETDEWEB)

Department of Foreign Affairs and International Trade services designed to assist businesses to effectively operate in global markets, were described. The goal of the Department is to give strategic targeted information that extends beyond export opportunities to include market access, investment, strategic alliances, technology transfer and competitiveness issues. These services constitute the Department`s Trade Commissioner Service, a network of 600 officers, deployed in 128 embassies and consulates worldwide to support Canadian business development initiatives across 16 sectors of the government`s International Trade Business Plan (ITBP). The Trade Commissioner Service programs include the WIN exporters database, a trade inquiries sourcing team, International Financial Institutions (IFI) projects, and the Program for Export Market Development (PEMD). A series of Sectoral Advisory Groups on International Trade (SAGIT) have been established to facilitate the needs ...

1995-12-31

157

Fiscal year 1987 program plan  

Energy Technology Data Exchange (ETDEWEB)

The Defense TRU Waste Program (DTWP) is the focal point for the Department of Energy in national planning, integration, operation, and technical development for TRU waste management. The scope of this program extends from the point of TRU waste generation through delivery to a permanent repository. The TRU program maintains a close interface with repository development to ensure program compatibility and coordination. The defense TRU program does not directly address commercial activities that generate TRU waste. Instead, it is concerned with providing alternatives to manage existing and future defense TRU wastes. The FY 87 Program Plan is consistent with the Defense TRU Waste Program goals and objectives stated in the Defense Transuranic Waste Program Strategy Document, January 1984. The roles of participants, the responsibilities and authorities for Operations, and Research ...

1986-12-01

158

Production of rare earth enriched isotopes and americium 242 using metallphthalocyanines  

International Nuclear Information System (INIS)

A technique of producing radioactive isotopes of rare earth elements (r.e.e.) and carrier free "2"4"2Am is suggested. The technique makes use of ''sandwich'' phthalocya=- nine complexes of r.e.e. and americium placed on sorbent. This is a new type of r.e.e. compounds and actinides (C_3_2H_1_6N_8)_2M (M is a metal ion) which are thermally, radiationally and chemically stable, dissolve well in some organic solvents and do not dissolve in water. Radiation and chemically stable activated carbon is used as a sorbent carrier. After irradiation the target is treated by a weakly acid solution or complex-former solution. Radioactive atoms formed due to (n, #gamma#)-reaction and desoleting the complex because of recoil transfer into the solution. When irradiating in the flux of 10"1"3 neutr./cm"2 x s for 1 hour it is possible to produce radioactive isotopes with the yield from 20 to 90%, for example "1"6"0Tb, "1"6"6Ho with enrichment ...

159

Matching the needs of a nation: The strategic roles of indicators for decisionmaking  

Energy Technology Data Exchange (ETDEWEB)

Indicators are important tools for communicating and making accessible scientific and technical information to policymakers and the general public. They therefore play an important role in transforming information into action. Worldwide, many initiatives are underway to construct indicators for a variety of purposes, including those for reporting on sustainable development. This paper briefly describes the attempts made so far, but stresses that the users of the indicators should play a greater role in indicator construction. In developing countries, a substantial lack of data has meant that specific policy formulation may develop without adequate technical input. In developed countries also, data gaps may hinder policy formulation, implementation, and evaluation. However, the development of indicators as tools to assist in the management of hazardous wastes and toxic chemicals is still in the early stages of formulation. A more imaginative program of indicators ...

1996-12-31

160

Accelerated aging tests of chromium containing amorphous hydrogenated carbon coatings for solar collectors  

Energy Technology Data Exchange (ETDEWEB)

Chromium containing amorphous hydrogenated carbon films (a-C : H/Cr) have been prepared by simultaneous rf plasma activated chemical vapour deposition of methane and magnetron sputtering of a chromium target. During deposition the substrates were heated (up to 300C) and DC biased (-200 and -600 V) in order to obtain films with high chemical stability. Constant temperature tests were performed at 250C in air with coatings deposited on silicon substrates. The degradation of the coatings was monitored by Raman spectroscopy and reflectance and transmission measurements. The main degradation mechanisms are discussed and the relevant parameters which improve the durability of the coatings are presented. Furthermore, the durability of solar selective, multilayered coatings which were deposited on copper sheets was investigated. Based on accelerated aging tests at different temperature loads in air (at 220C, 250C and 300C) and in a ...

1998-07-13

161

State of the Art Laser Induced Breakdown Spectroscopy  

International Nuclear Information System (INIS)

Methods currently being used or developed for the elemental analysis of materials are chemical analysis, non-destructive inspection and calorimetry. The chemical analysis, which removes high-level radioactive elements through chemical treatments and then performs the quantitative analysis using the ICP-MS(Inductively Coupled Plasma - Mass Spectrometer) or the ID-MS(Isotope Dilution Mass Spectrometer), is recognized the most accurate. However, it requires a long, complex pre-treatment process in which a mass spectrometer could be contaminated. To solve this problem, a new method, which can be performed with high-level radioactivity and at high temperature, was desired. Such a method should also have the same accuracy as the chemical analysis, with a less possibility for instruments to be contaminated. In addition, as interests in the environment and the life quality are increased, a detailed analysis on ...

162

Optical chemical sensors for atmospheric pollutants based on nano porous materials: application to the formaldehyde and the other carbonyl compounds; Capteurs chimiques a transduction optique de polluants atmospheriques a base de materiaux nanoporeux: application au formaldehyde et autres composes carbonyles  

Energy Technology Data Exchange (ETDEWEB)

Formaldehyde, a well-identified indoor pollutant, was recently classified as carcinogenic. New regulations for the air quality are expected and therefore there is a need for low-cost sensors, sensitive and selective with a fast response time for the detection of formaldehyde at ppb level. In the present work, we had developed a chemical sensor based on nano-porous matrices doped with Fluoral-P and optical methods of detection. The nano-porous matrices, elaborated via the Sol-Gel process, display nano-pores whose cavity is tailored for the trapping of the targeted pollutant. They provide a first selectivity with the discrimination of the pollutants by their size. A second selectivity is obtained with a molecular probe, Fluoral-P, which reacts specifically with formaldehyde leading to the 3,5- di-acetyl-1,4-dihydro-lutidine (DDL). The kinetics of formation of DDL was studied as function of many parameters such as the concentration of Fluoral-P in ...

2006-12-15

163

Impact of diisobutyl phthalate and other PPAR agonists on steroidogenesis and plasma insulin and leptin levels in fetal rats  

International Nuclear Information System (INIS)

Endocrine disrupting chemicals can induce malformations and impairment of reproductive function in experimental animals and may have similar effects in humans. Recently, the environmental obesogen hypothesis was proposed, suggesting that environmental chemicals contribute to the development of obesity and insulin resistance. These effects could be related to chemical interaction with nuclear receptors such as the peroxisome proliferator activated receptors (PPARs). As several testosterone-reducing drugs are PPAR activators, we aimed to examine whether four PPAR agonists were able to affect fetal testosterone production and masculinization of rats. Additionally, we wished to examine whether these chemicals affected fetal plasma levels of insulin and leptin, which play important roles in the developmental programming of the metabolic system. Pregnant Wistar rats were exposed from gestation day (GD) 7-21 ...

2008-09-04

164

EDI as a Treatment Module in Recycling Spent Rinse Waters  

Energy Technology Data Exchange (ETDEWEB)

Recycling of the spent rinse water discharged from the wet benches commonly used in semiconductor processing is one tactic for responding to the targets for water usage published in the 1997 National Technology Roadmap for Semiconductors (NTRS). Not only does the NTRS list a target that dramatically reduces total water usage/unit area of silicon manufactured by the industry in the future but for the years 2003 and beyond, the NTRS actually touts goals which would have semiconductor manufacturers drawing less water from a regional water supply per unit area of silicon manufactured than the quantity of ultrapure water (UPW) used in the production of that same silicon. Achieving this latter NTRS target strongly implies more widespread recycling of spent rinse waters at semiconductor manufacturing sites. In spite of the fact that, by most metrics, spent rinse waters are of much higher purity than incoming municipal waters, ...

1999-08-11

166
168

Computational Challenges in miRNA Target Predictions: To Be or Not to Be a True Target?  

UK PubMed Central (United Kingdom)

All microRNA (miRNA) target—finder algorithms return lists of candidate target genes. How valid is that output in a biological setting? Transcriptome analysis has proven to be a useful approach...Full Text Available

2009-01-01

169
170

When autophagy meets viruses: a double-edged sword with functions in defense and offense  

UK PubMed Central (United Kingdom)

Autophagy is a ubiquitous catabolic process that ensures organism’s well-being by sequestering a wide array of undesired intracellular constituents into double-membrane vesicles termed...Full Text Available

2010-12-01

171

Unbiased Transcriptional Comparisons of Generalist and Specialist Herbivores Feeding on Progressively Defenseless Nicotiana attenuata Plants  

UK PubMed Central (United Kingdom)

BackgroundHerbivore feeding elicits dramatic increases in defenses, most of which require jasmonate (JA) signaling, and against which specialist herbivores are thought to be better...Full Text Available

172

The Harris M. Schurmeier Collection, 1970-1986 3.0 cubic ... - NASA  

Science.gov (United States)

SDI was a space-based defense system designed to ... satellites that could detect a massive nuclear launch within seconds, orbiting laser weapons to destroy the ..... AIAA Washington Conference, memorandum from T. W. Hamilton to H. ...

173

Sunny days! - Johnson Space Center - NASA  

Science.gov (United States)

May 18, 2001 ... Jeff Ashby, a Navy captain and veteran of ..... with the Department of Defense to acquire enough ..... Protection Handbook (Chapter 404). Each ..... x35416 or go to the website: http://www.ghg.net/cbr/jscas/ ...

174

Structure and Reaction Mechanism of Basil Eugenol Synthase  

UK PubMed Central (United Kingdom)

Phenylpropenes, a large group of plant volatile compounds that serve in multiple roles in defense and pollinator attraction, contain a propenyl side chain. Eugenol synthase (EGS) catalyzes the reductive...Full Text Available

175

Stress and Stress-Induced Neuroendocrine Changes Increase the Susceptibility of Juvenile Oysters (Crassostrea gigas) to Vibrio splendidus  

UK PubMed Central (United Kingdom)

Oysters are permanently exposed to various microbes, and their defense system is continuously solicited to prevent accumulation of invading and pathogenic organisms. Therefore, impairment of the animal's...Full Text Available

2001-05-01

176

Sediments transport and balance in coastal line; Trasporto solido ed equiliberio della linea di costa  

Energy Technology Data Exchange (ETDEWEB)

The erosion phenomena of coastal regions in Italy and in the world is remarkable from the environmental point of view. Are showed activities of mechanical defense and numerical models to solve complex problem.

1996-11-01

177

Robust Defense Against Small Boat Attacks.  

Science.gov (United States)

Nearly a decade after the small boat attacks against the USS Cole (in 2000) and M/V Limburg (in 2002) in Yemen, small vessels continue to pose a security threat. In part, this is due to the ease of camouflage and the high frequency of small vessels operat...

2010-01-01

178

RIN4-like proteins mediate resistance protein-derived soybean defense against Pseudomonas syringae  

UK PubMed Central (United Kingdom)

Resistance (R) protein mediated recognition of pathogen avirulence effectors triggers signaling that induces a very robust form of species-specific immunity in plants. The soybean Rpg1-b protein mediates...Full Text Available

2010-11-01

179

Planetary Defense ... - Asteroid Comet Impact Hazards - NASA  

Science.gov (United States)

Mar 1, 2004 ... For a summary of papers from a 4-day AIAA conference held February ... m is less than $400 million, with both ground-based and space-based options possible. .... from concerns about a new generation of nuclear weapons. ...

180

ORNL nuclear waste programs annual progress report for period ending September 30, 1982  

Energy Technology Data Exchange (ETDEWEB)

Research progress is reported in 20 activities under the headings: spent fuels, defense waste management, commercial waste management, remedial action, and conventional reactors. Separate entries were prepared for each activity.

1983-05-01

181

Nuclear receptor ERR? and coactivator PGC-1? are effectors of IFN-?-induced host defense  

UK PubMed Central (United Kingdom)

Macrophage activation by the proinflammatory cytokine interferon-γ (IFN-γ) is a critical component of the host innate response to bacterial pathogenesis. However, the precise nature...Full Text Available

2007-08-01

182

Modulation of ASK1 expression during overexpression of Trx and HSP70 in stressed fish liver mitochondria  

UK PubMed Central (United Kingdom)

Mitochondrial heat shock protein 70 (mtHSP70) is found to play a primary role in cellular defense against physiological stress like exposure to environmental contaminants and helpful in the maintenance...Full Text Available

2009-09-01

183

Mechanism of Host Defense Suppression Induced by Viral Infection: Mode of Action of Inosiplex as an Antiviral Agent  

UK PubMed Central (United Kingdom)

The mechanism of influenza virus (INFV)-induced immunosuppression and the mode of inosiplex action against INFV infection were studied. INFV suppressed both anti-lipopolysaccharide and anti-sheep erythrocyte...Full Text Available

1982-10-01

184

Knockout of Arabidopsis ACCELERATED-CELL-DEATH11 encoding a sphingosine transfer protein causes activation of programmed cell death and defense  

UK PubMed Central (United Kingdom)

We describe the lethal, recessive accelerated-cell-death11 Arabidopsis mutant (acd11). Cell death in acd11 exhibits characteristics of animal apoptosis...Full Text Available

2002-02-15

185

Generation and control of sound bullets with a nonlinear acoustic lens  

UK PubMed Central (United Kingdom)

Acoustic lenses are employed in a variety of applications, from biomedical imaging and surgery to defense systems and damage detection in materials. Focused acoustic signals, for example, enable ultrasonic...Full Text Available

2010-04-20

186

Food as a Component of National Defense Strategy  

Science.gov (United States)

... As noted by Emma Rothschild: ... 24. Emma Rothschild, "Food Politics," Foreign Affairs, 54 (January 1976),285·86. 25. Forecast 90, pp. I1·31, 32. 26. ...

2011-05-15

187

Expert Knowledge in a Joint Task Force Headquarters.  

Science.gov (United States)

Officers receive service-specific education and undergo experiences within their components that provide the expert knowledge that enables them to operate in their respective military departments. Given the Department of Defense (DoD) emphasis on service ...

2005-01-01

188

Eugenol and isoeugenol, characteristic aromatic constituents of spices, are biosynthesized via reduction of a coniferyl alcohol ester  

UK PubMed Central (United Kingdom)

Phenylpropenes such as chavicol, t-anol, eugenol, and isoeugenol are produced by plants as defense compounds against animals and microorganisms and as floral attractants of pollinators....Full Text Available

2006-06-27

189

Efficient Phagocytosis Requires Triacylglycerol Hydrolysis by Adipose Triglyceride Lipase*  

UK PubMed Central (United Kingdom)

Macrophage phagocytosis is an essential biological process in host defense and requires large amounts of energy. To date, glucose is believed to represent the prime substrate for ATP production in macrophages....Full Text Available

2010-06-25

190

Efficacy of antimicrobial therapy in experimental rat pneumonia: effects of impaired phagocytosis.  

UK PubMed Central (United Kingdom)

The importance of intact host defense mechanisms for successful antimicrobial therapy was investigated in an animal model. Recovery from lobar pneumococcal pneumonia as a result of penicillin therapy...Full Text Available

1979-07-01

191

DefenseLINK News: Fourth Haiti Contingency Exercise  

Science.gov (United States)

... exercise to Port Au Prince, Haiti, begins Friday, April 11, 1997, when a company-sized element from the Army's 82nd Airborne Division from Fort ...

192

Defense Department Cyber Efforts: More Detailed Guidance ...  

Science.gov (United States)

... 2 Joint Pub. 5-0 (Dec. 26, 2006); CJCSM 3122.01A (Sept. 29, 2006, current as of Oct. 11, 2008); and CJCSM 3122.03C (Aug. 17, 2007). Page 31. ...

2011-05-01

193

DOD (Department of Defense) Acquisition: Case Study of the MILSTAR (Military Strategic and Tactical Relay) Satellite Communications System.  

Science.gov (United States)

The study of the Military Strategic and Tactical Relay (MILSTAR) program focuses on the role of the program manager and contracting officer in developing the acquisition strategy.

1986-01-01

194

Concentric Versus Enhanced Eccentric Hamstring Strength Training: Clinical Implications  

UK PubMed Central (United Kingdom)

Objective: Hamstring injuries can be quite debilitating and often result in chronic problems. Eccentric muscle actions are often the last line of defense against muscle injury...Full Text Available

1998-07-01

195

Complement Evasion by Borrelia burgdorferi: Serum-Resistant Strains Promote C3b Inactivation  

UK PubMed Central (United Kingdom)

The most characteristic features of the Lyme disease pathogens, the Borrelia burgdorferi sensu lato (s.l.) group, are their ability to invade tissues and to circumvent the immune defenses...Full Text Available

2001-06-01

196

Classified Information Policy and Executive Order 13526.  

Science.gov (United States)

Recently, there have been multiple high-profile incidents involving the release of classified government information. Perhaps most prominent was Wikileaks.org's unauthorized publication of more than 600,000 classified Department of Defense documents. Such...

2010-01-01

197

Behavioral genomics of honeybee foraging and nest defense  

UK PubMed Central (United Kingdom)

The honeybee has been the most important insect species for study of social behavior. The recently released draft genomic sequence for the bee will accelerate honeybee behavioral genetics. Although...Full Text Available

2007-04-01

198

Antioxidant Defenses Predict Long-Term Survival in a Passerine Bird  

UK PubMed Central (United Kingdom)

BackgroundNormal and pathological processes entail the production of oxidative substances that can damage biological molecules and harm physiological functions. Organisms have evolved...Full Text Available

199

An Investigation of the Storage and Biosynthesis of Phenylpropenes in Sweet Basil1  

UK PubMed Central (United Kingdom)

Plants that contain high concentrations of the defense compounds of the phenylpropene class (eugenol, chavicol, and their derivatives) have been recognized since antiquity as important spices for...Full Text Available

2001-02-01

200

48 CFR 228.370 - Additional clauses.  

Science.gov (United States)

...Acquisition Regulations System 3 2010-10-01...Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF...assumption of risk for transportation by conveyance on...Missiles, and Space Launch Vehicles,...

2010-10-01

201

32 CFR 185.4 - Policy.  

Science.gov (United States)

...undertake missions and tasks (on either a...Secretary of Defense to task the DoD Components...the Chairman of the Joint Chiefs of Staff any commitment of military forces assigned to the Unified... (9) Military forces employed in MSCA...approval from higher headquarters, local military...

2010-07-01

202

Development of the SRS environmental counting laboratory gamma spectroscopy system  

International Nuclear Information System (INIS)

The Savannah River Site (SRS), one of several U.S. Department of Energy (DOE) facilities, produces nuclear materials for national defense and for other government and civilian uses. SRS ceased production of defense materials in 1988, and the site's main activities now involve waste management and environmental restoration. These programs have generated extensive effluent monitoring and environmental surveillance programs for the Environmental Monitoring Section (EMS), which performs #approx#105,000 radiological analyses on 30,000 samples a year. Gamma spectroscopy is performed on an estimated 10,000 samples annually. This report describes a program to develop and improve the EMS system.

1996-06-16

203

[Development of efficient DNA isolation procedures for Cryptosporidium and Trichinella PCR detection in fecal samples].  

Science.gov (United States)

PCR detection of genetic material of the parasites present in faeces may be an alternative for microscopic and serological tests routinely used for diagnosing parasitic enteral infections. However, small amount of target DNA combined with low efficiency of total DNA extraction, and presence of PCR inhibitors in the samples to be amplified, may cause false negative detection results. The aim of this work was to evaluate the impact of DNA isolation procedure used on the amplification of DNA fragments from the genomes of protozoan Cryptosporidium parvum and the nematode Trichinella spiralis. Two methods based on different principles of biological material lysis were evaluated; NucliSENS miniMAG employing simultaneously applied chemical lysis and mechanical disruption or mechanical disruption followed by enzymatic lysis in case of QIAamp DNA Stool Mini Kit. Both of the analyzed systems for nucleic acids purification allowed isolation of DNA from ...

2009-01-01

204

Industrial Technologies Program: Chemicals  

Science.gov (United States)

Efficiency and Renewable Energy EERE Home | Programs & Offices | Consumer Information Chemicals Search Search Help Chemicals EERE » Industrial Technologies Program » Chemicals...

2011-10-01

205

Defense Waste and Environmental Restoration Program Plan: Defense Waste Management Division  

Energy Technology Data Exchange (ETDEWEB)

The DEFENSE WASTE MANAGEMENT PROGRAM has been chartered by the Department of Energy (DOE) to receive, reduce, store, and maintain all radioactive defense waste generated by Hanford and received from offsite DOE contractors in a safe condition and in accordance with DOE and Westinghouse Hanford Company (WHC) standards. These activities are accomplished through the use of TRU retrievable storage sites, solid waste burial grounds, liquid waste storage tanks, capsule storage pools, and other low-level waste disposal methods. Continuous and/or periodic surveillance is maintained. Through the use of improved packaging methods, evaporator-crystallization and capsule production waste has been and continues to be put in a safe and economic storage condition pending future reprocessing or final disposition. For this Program Plan, the scope of Defense Waste Management programmatic activities has been organized into three general ...

1988-09-01

206

Type of brown coal from North-Bohemian basin effect to quality of pyrolysis products  

Energy Technology Data Exchange (ETDEWEB)

By increasing the price of crude oil and natural gas and the decline in their stock a possibility of more intense use of coal reserves as a feedstock not only for energy purposes but also as a feedstock source for other industries, mainly chemical and steel industry, is opening up. At present brown coal exploited in the Czech Republic is explicitly burned in the power sources of various outputs. Coal pyrolysis under the defined conditions may be an outstanding way of non-energetic brown coal processing. The target of our work was to determine the behaviour of various types of brown coal from the North Bohemian Basin under the pyrolysis up to the temperature 750{sup o}C. At the same time, qualitative parameters of the pyrolysis products in dependence on the features of the input brown coal were observed. Various types of brown coal were used for the pyrolysis tests differing mainly in the content of ash, sulphur and tar. Within the work mass ...

2005-07-01

207

Separation Science and Technology. Semiannual progress report, April 1993--September 1993  

Energy Technology Data Exchange (ETDEWEB)

This document reports on the work done by the Separations Science and Technology Programs of the Chemical Technology Division, Argonne National Laboratory, in the period April-September 1993. This effort is mainly concerned with developing the TRUEX process for removing and concentrating actinides from acidic waste streams contaminated with transuranic (TRU) elements. The objectives of TRUEX processing are to recover valuable TRU elements and to lower disposal costs for the nonTRU waste product of the process. Other projects are underway with the objective of developing (1) evaporation technology for concentrating radioactive waste and product streams such as those generated by the TRUEX process, (2) treatment schemes for liquid wastes stored or being generated at Argonne, (3) a process based on sorbing modified TRUEX solvent on magnetic beads to be used for separation of contaminants from radioactive and hazardous waste streams, and (4) a process that uses ...

1996-01-01

208

Rapid toxicity testing based on mitochondrial respiratory activity  

Energy Technology Data Exchange (ETDEWEB)

The need exists for rapid and inexpensive methods to determine the health effects of environmental contaminants on biological systems. One of the current research approaches for assessing cytotoxicity is to monitor the respiratory activity of the mitochondrion, a sensitive, nonspecific subcellular target site. Detected changes in mitochondrial function after the addition of a test chemical could be correlated to toxic effects. Mitochondrial respiration can be characterized by three indices: state 3 and state 4 respiratory rates, and the respiratory control ratio (RCR). State 4, the idle or resting state, results when coupled mitochondrial respire in a medium containing inorganic phosphate and a Kreb's cycle substrate in the absence of a phosphate acceptor such as adenosine diphosphate (ADP). In the presence of ADP the respiration rate increases to a maximum (state 3), accompanied by phosphorylation of ADP to adenosine triphosphate ...

1990-05-01

209

Radiochemical separation of no-carrier-added {sup 177}Lu as produced via the {sup 176}Ybn,{gamma}{sup 177}Yb{yields}{sup 177}Lu process  

Energy Technology Data Exchange (ETDEWEB)

The {sup 176}Ybn,{gamma}{sup 177}Yb-{beta}{sup -}{yields}{sup 177}Lu process was investigated to provide no-carrier-added (nca) {sup 177}Lu. The radiochemical separation of the {sup 177}Lu from the macro-amounts of the ytterbium target based on the cementation process, i.e. the selective extraction of Yb by Na(Hg) amalgam from Cl{sup -}/CH{sub 3}COO{sup -} electrolytes, followed by a final cation exchange purification. The cementation separation process provides a decontamination factor of Yb(III) of 10{sup 4}, the cation exchange purification adding a decontamination factor of >10{sup 2}. The nca {sup 177}Lu is available in radiochemically pure form despite the chemical similarity of the lanthanides with 75{+-}5% overall separation yield within 4-5 h. It can be used to synthesise nca {sup 177}Lu labelled radiotherapeuticals.

2000-09-15

210

Development of a novel mouse tk{sup +/-} embryonic stem cell line for use in mutagenicity studies  

Energy Technology Data Exchange (ETDEWEB)

A tk{sup +/-} mouse embryonic stem (ES) cell line, designated 1G2, has been created in which one allele of the thymidine kinase (tk) gene was inactivated by targeted homologous recombination. This line is an analog of the mouse lymphoma tk{sup +/-} L5178Y cell line, which is used widely to assess the mutagenicity of chemical agents. Treatment of 1G2 cells with the alkylating agent N-ethyl-N-nitrosourea (ENU) resulted in a dose-related increase in tribluorothymidine-resistant colonies. Mutant frequencies of 152 and 296 per 10{sup 6} cells were determined for 0.1 and 0.3 mg/ml doses of ENU, compared with a spontaneous mutant frequency of 15 per 10{sup 6} cells. The data indicate that tk{sup +/-} 1G2 ES cells may be useful for the creation of a transgenic mouse model for assessing in vivo mutation using an endogenous autosomal gene. 45 refs., 2 figs., 1 tab.

1996-12-31

211

Final Report for "Investigation of reaction networks and active sites in bio-ethanol steam reforming over Co-based catalysts" with all publications attached.  

Energy Technology Data Exchange (ETDEWEB)

This was a university-based research project in support of distributed reforming production technologies for hydrogen. Our objective was to examine the steam reforming of bio-ethanol and other related bio-derived liquids over non-precious metal catalyst systems to enable small-scale distributed hydrogen production technologies from renewable sources. The study targeted development of a catalytic system that does not rely on precious metals and that can be active in the 350-550 C temperature range, with high selectivity and high stability. To this end, we adopted a multi-prong research strategy, that included catalyst formulation and synthesis, detailed catalyst characterization, reaction kinetics and reaction engineering, molecular modeling and economic analysis studies. Our approach was an iterative one, where the knowledge gained in one aspect of the study was utilized to modify and fine-tune catalyst development. The research addressed many fundamental and ...

2011-03-31

212

Properties and performance of new metastable Ti-B-C-N hard coatings prepared by magnetron sputtering  

Energy Technology Data Exchange (ETDEWEB)

Thin films of new metastable materials from the system Ti-B-C-N were deposited on metallic substrates by d.c. magnetron sputtering in different Ar+N{sub 2} atmospheres. The multiphase compound targets used were based on various compositions on the TiC-TiB{sub 2} and TiB{sub 2}-C tie lines of the Ti-B-C phase diagram. The structure and chemical composition of the films were characterized by electron microprobe analysis, depth profiling Auger electron spectroscopy, X-ray diffraction and transmission electron microscopy. The hardness, critical load of failure and the tribological behavior of the coatings were investigated. Superhard single-phase crystalline metastable Ti-B-C-N layers with hardness values exceeding 5000 HV{sub 0.05} and extremely low sliding wear against 100Cr6 and Al{sub 2}O{sub 3} counterparts could be produced by reactive sputtering of various TiC-TiB{sub 2} targets in Ar+N{sub 2} atmospheres with low ...

1995-10-01

213

Instrumentation for monitoring and control of cycle chemistry for the steam-water circuits of fossil-fired and combined-cycle power plants  

Energy Technology Data Exchange (ETDEWEB)

A guidance document on the instrumentation for monitoring and control of cycle chemistry for the steam-water circuits of fossil-fired and combined-cycle power plants was developed within the IAPWS Power Cycle Chemistry Working Group. This technical guidance document has been authorized by the International Association for the Properties of Water and Steam (IAPWS) at its meeting in Doorwerth, The Netherlands, 6-11 September, 2009, for issue by its Secretariat. The members of the IAPWS are: Britain and Ireland, Canada, the Czech Republic, Denmark, France, Germany, Greece, Japan, Russia, and the United States of America, and the associate members Argentina and Brazil, Italy, and Switzerland. In order to achieve suitable chemical conditions in steam-water circuits it is essential to establish reliable monitoring of key parameters on every plant. This enables the demonstration of operation within cycle chemistry targets, and alerts the operators to ...

2009-10-15

214

Chemical Reactor Diagnostics  

International Science & Technology Center (ISTC)

Development of Methods and Apparatus for Processes Diagnostics in Plasma Reactors at the Neutralization of Chemical Herbiside and Pestiside

215

Chemical Emergencies  

Medline Plus

English - Chemical Emergencies Click to Stop Video Click to Start Video To Listen to the Audio or ...

216

Targeting Prostate Cancer Cells In Vivo Using a Rapidly Internalizing Novel Human Single-Chain Antibody Fragment  

UK PubMed Central (United Kingdom)

Human antibodies targeting prostate cancer cell surface epitopes may be useful for imaging and therapy. The objective of this study was to evaluate the tumor targeting of an internalizing human...Full Text Available

2010-03-01

218

Isoform-level microRNA-155 target prediction using RNA-seq  

UK PubMed Central (United Kingdom)

Computational prediction of microRNA targets remains a challenging problem. The existing rule-based, data-driven and expression profiling approaches to target prediction are mostly approached from the...Full Text Available

2011-05-01

219

Delineating Bacteriostatic and Bactericidal Targets in Mycobacteria Using IPTG Inducible Antisense Expression  

UK PubMed Central (United Kingdom)

In order to identify novel high value antibacterial targets it is desirable to delineate whether the inactivation of the target enzyme will lead to bacterial death or stasis. This knowledge is particularly...Full Text Available

220

A thermal hydraulic investigation on ADSR liquid lead target  

Energy Technology Data Exchange (ETDEWEB)

Computational fluid dynamics(CFD) code FLUENT was used to simulate the thermal hydraulic processes occurring in conceptual design of the accelerator-driven subcritical reactor(ADSR) liquid lead target. The purpose of the analysis is to investigate the thermal hydraulic characteristics of liquid lead as ADSR target material with various target geometries and injection locations of proton beam. In the calculation analysis, the local temperature of the liquid lead target rises to the boiling temperature very rapidly. When the proton beam is injected from the bottom of the target system, the duration time to reach the boiling temperature is longer and the temperature distribution is flatter than other cases.

1998-05-01

221

The response of small scale rigid targets to shallow buried explosive detonations  

British Library Electronic Table of Contents (United Kingdom)

Experimental and computational investigations were performed in order to better understand the mechanical response of rigid targets with various geometries to the detonation of shallow buried explosives. The motion of the targets was measured by use of high-speed digital video photography. This work involved flat targets, targets that were downwardly convex, and targets that were downwardly concave with explosive charges located at various positions beneath the targets. It was observed that, in general, angled hulls - whether downwardly concave or convex - tended to reduce the amount of momentum imparted to the center of mass of the targets. Computations were performed by use of an arbitrary Langrangian-Eulerian treatment in a nonlinear finite element code. A model based on quasi-static te...

2011-01-01

222

Targeting a Ruthenium Complex to the Nucleus with Short Peptides  

UK PubMed Central (United Kingdom)

In an effort to develop octahedral metal complexes as chemotherapeutic and diagnostic agents targeted to DNA, it is critical to optimize the properties of their cellular uptake. Appending d-octaarginine...Full Text Available

2010-05-15

223

Target stations and beam dumps for the CERN SPS  

International Nuclear Information System (INIS)

The design of the absorber blocks for internal and external dumping of the SPS proton beam is discussed. In addition, the external target stations for slow and fast extracted proton beams are described.

1977-03-16

224

Suitability of a New Plant Invader as a Target for Biological Control in Florida  

Science.gov (United States)

... L. Sutton. 2000. Is the aquatic weed hygrophila, Hygrophila polysperma (Polemoniales: Acanthaceae), a suitable target for classical biological ... ...

225

Nato SCI-12 on Camouflage Evaluation Workshop on Search and Target ...  

Science.gov (United States)

Nato SCI-12 on Camouflage Evaluation Workshop on Search and Target Acquisition The Netherlands, June 1999. Image Discrimination Models for Object Detection ...

226

FOR THIN AND THICK TARGETS - NASA Technical Report Server (NTRS)  

Science.gov (United States)

By W. Wayne Scott. Langley Research Center. SUMMARY. Thin- and thick-target bremsstrahlung spectra are presented for electron energies up to 7.0 MeV. ...

227

Utilizing the right mix of environmental cleanup technologies  

International Nuclear Information System (INIS)

The Savannah River Site (SRS) is a 310-square-mile United States Department of Energy nuclear facility located along the Savannah River near Aiken, South Carolina. During operations, which started in 1951, hazardous substances (chemicals and radionuclides) were released to the environment. The releases occurred as a result of inadvertent spills and waste disposal in unlined pits and basins which was common practice before environmental regulations existed. The hazardous substances have migrated to the vadose zone and groundwater in many areas of the SRS, resulting in 515 waste units that are required by environmental regulations, to undergo characterization and, if needed, remediation. In the initial years of the SRS environmental cleanup program (early 1990's), the focus was to use common technologies (such as pump and treat, air stripping, excavation and removal) that actively and tangibly removed contamination. Exclusive use of these technologies required ...

2007-09-02

228

Structured Interview of Personality Organization (STIPO): preliminary psychometrics in a clinical sample.  

Science.gov (United States)

In this article, we describe the development and preliminary psychometric properties of the Structured Interview of Personality Organization (STIPO), a semistructured interview designed for the dimensional assessment of identity, primitive defenses, and reality testing, the three primary content domains in the model of personality health and disorder elaborated by Kernberg (1984; Kernberg & Caligor, 2005). Results of this investigation, conducted in a clinical sample representing a broad range of personality pathology, indicate that identity and primitive defenses as operationalized in the STIPO are internally consistent and that interrater reliability for all 3 content domains is adequate. Validity findings suggest that the assessment of one's sense of self and significant others (Identity) is predictive of measures of positive and negative affect, whereas the maladaptive ways in which the subject uses his or her objects for purposes of ...

2010-01-01

229

Prediction of Chemicals Ecotoxicity  

International Science & Technology Center (ISTC)

Computer-Aided Prediction of Chemical Ecotoxicity on the basis of Quantitative Structure-Activity Relationships with the Use of Physico-Chemical Descriptors, Including H-bond Parameters

230

Cell proliferation and chemical carcinogenesis: symposium overview.  

UK PubMed Central (United Kingdom)

Cancer, by definition, is a proliferative disease. The fundamental scientific issue explored at the international symposium "Cell Proliferation and Chemical Carcinogenesis" was the impact of chemically...Full Text Available

1993-12-01

231

CHEMICAL LEUCODERMA: INDIAN SCENARIO, PROGNOSIS, AND TREATMENT  

UK PubMed Central (United Kingdom)

Chemical leucoderma is an industrial disorder in developed countries and the common causative chemicals are phenols and catechols. Due to stringent controls and preventive measures the incidence has...Full Text Available

2010-07-01

232

Special Nevada report  

Energy Technology Data Exchange (ETDEWEB)

This report is submitted to Congress by the Secretary of the Air Force, the Secretary of the Navy, and the Secretary of the Interior pursuant to Section 6 of the Military Lands Withdrawal Act of 1986. It contains an analysis and evaluation of the effects on public health and safety resulting from DOD and Department of Energy (DOE) military and defense-related uses on withdrawn public lands in the State of Nevada and in airspace overlying the State. This report describes the cumulative impacts of those activities on public and private property in Nevada and on plants, fish and wildlife, cultural, historic, scientific, recreational, wilderness and other resources of the public lands of Nevada. An analysis and evaluation of possible measures to mitigate the cumulative effects of the withdrawal of lands and the use of airspace in Nevada for defense-related purposes was conducted, and those considered practical are listed.

1991-09-23

233

Network Security Mechanisms Utilizing Dynamic Network Address Translation LDRD Project  

Science.gov (United States)

A new protocol technology is just starting to emerge from the laboratory environment. Its stated purpose is to provide an additional means in which networks, and the services that reside on them, can be protected from adversarial compromise. This report has a two-fold objective. First is to provide the reader with an overview of this emerging Dynamic Defenses technology using Dynamic Network Address Translation (Dynat). This ''structure overview'' is concentrated in the body of the report, and describes the important attributes of the technology. The second objective is to provide a framework that can be used to help in the classification and assessment of the different types of dynamic defense technologies along with some related capabilities and limitations. This information is primarily contained in the appendices.

2002-11-01

234

Effects of nitrogen fertilization on forest trees in relation to insect resistance and to red-listed insect species  

Energy Technology Data Exchange (ETDEWEB)

Ecosystems worldwide are experiencing unprecedented nitrogen enrichment through fertilization and pollution. While longterm ecological consequences are difficult to predict, it seems that plants and animals adapted to nitrogen-limited environments are at particular risk from these changes. This report summarizes the limited body of literature which addresses this important topic. From a herbivoreAes perspective, fertilization increases the nutritional quality of host plant tissues. In some cases fertilization has lead to decreased production of defensive compounds. How this affects populations of insects is unclear because fertilization affects not only herbivores but their natural enemies. This report outlines how fertilization affects tree processes such as growth, photosynthesis, and production of defensive compounds. The many factors that affect insect repsonse to fertilization and the difficulties in assessing how fertilization affects ...

2001-10-01

235

Changes in Energy Metabolism and Antioxidant Defense Systems During Seed Germination of the Weed Species Ipomoea triloba L. and the Responses to Allelochemicals  

British Library Electronic Table of Contents (United Kingdom)

The relationships between changes in energy metabolism and the antioxidant defense system in the weed species Ipomoea triloba L. during seed germination and early seedling growth were investigated. The effects of some common allelochemicals on these parameters also were studied. Respiratory activity and the activities of alcohol dehydrogenase, superoxide dismutase, catalase, guaicol peroxidase, ascorbate peroxidase, glutathione reductase, and lipoxygenase were measured. Mitochondrial oxidative phosphorylation resumed shortly after the seed imbibition period, as indicated by considerable KCN-sensitive respiratory activity in embryos of I. triloba. The occurrence of superoxide dismutase, catalase, guaicol peroxidase, and lipoxygenase activities in the embryos, along with significant KCN-inse...

2011-01-01

236

Briefing Book, Interagency Geothermal Coordinating Council (IGCC) Meeting of April 28, 1988  

Energy Technology Data Exchange (ETDEWEB)

The IGCC of the U.S. government was created under the intent of Public Law 93-410 (1974) to serve as a forum for the discussion of Federal plans, activities, and policies that are related to or impact on geothermal energy. Eight Federal Departments were represented on the IGCC at the time of this meeting. The main presentations in this report were on: Department of Energy Geothermal R&D Program, the Ormat binary power plant at East Mesa, CA, Potential for direct use of geothermal at Defense bases in U.S. and overseas, Department of Defense Geothermal Program at China Lake, and Status of the U.S. Geothermal Industry. The IGCC briefing books and minutes provide a historical snapshot of what development and impact issues were important at various time. (DJE 2005)

1988-04-28

237

Target R and D at JAERI  

Energy Technology Data Exchange (ETDEWEB)

We proposed a solid and a mercury target concepts through the preliminary conceptual design. To feasible these concepts, analysis and experimental works are being carried out. This paper introduces an outline of present status of target R and D such as heat transfer augmentation experiments for the solid target, mercury flow tests with a loop of maximum flow rate of 15L/min, flow pattern measurements for a cold source moderator etc. as well as preliminary conceptual design works. (author)

1999-03-01

242

Phase I Report: DARPA Exoskeleton Program  

Science.gov (United States)

The Defense Advanced Research Projects Agency (DARPA) inaugurated a program addressing research and development for an Exoskeleton for Human Performance Augmentation in FY!2001. A team consisting of Oak Ridge National Laboratory, the prime contractor, AeroVironment, Inc., the Army Research Laboratory, the University of Minnesota, and the Virginia Polytechnic Institute has recently completed an 18-month Phase I effort in support of this DARPA program. The Phase I effort focused on the development and proof-of-concept demonstrations for key enabling technologies, laying the foundation for subsequently building and demonstrating a prototype exoskeleton. The overall approach was driven by the need to optimize energy efficiency while providing a system that augmented the operator in as transparent manner as possible (non-impeding). These needs led to the evolution of two key distinguishing features of this team's approach. The first is the ...

2004-01-21

243

Interpretation of data obtained from non-destructive and destructive post-test analyses of an intact-core column of culebra dolomite  

Energy Technology Data Exchange (ETDEWEB)

The U.S. Department of Energy (DOE) has been developing a nuclear waste disposal facility, the Waste Isolation Pilot Plant (WIPP), located approximately 42 km east of Carlsbad, New Mexico. The WIPP is designed to demonstrate the safe disposal of transuranic wastes produced by the defense nuclear-weapons program. Pefiormance assessment analyses (U.S. DOE, 1996) indicate that human intrusion by inadvertent and intermittent drilling for resources provide the only credible mechanisms for significant releases of radionuclides horn the disposal system. These releases may occur by five mechanisms: (1) cuttings, (2) cavings, (3) spallings, (4) direct brine releases, and (5) long- term brine releases. The first four mechanisms could result in immediate release of contaminant to the accessible environment. For the last mechanisq migration pathways through the permeable layers of rock above the Salado are important, and major emphasis is placed on the Culebra Member of the ...

1998-09-01

244

A He-gas Cooled, Stationary Granular Target  

CERN Document Server

In the CERN approach to the design of a neutrino factory, the repetition frequency of the proton beam is high enough to consider stationary solid targets as a viable solution for multi-MW beams. The target consists of high density tantalum spheres of 2 mm diameter which can efficiently be cooled by passing a high mass flow He-gas stream through the voids between the Ta-granules. Very small thermal shocks and stresses will arise in this fine grained structure due to the relatively long burst of 3.3 ms from the SPL-proton linac. In a quadruple target system where each target receives only one quarter of the total beam power of 4 MW, conservative temperature levels and adequate lifetimes of the target are estimated in its very high radiation environment. A conceptual design of the integration of the target into the magnetic horn-pion-collector is presented.

2003-01-01

255

Disruption of contact inhibition in rat liver epithelial cells by various types of AhR ligands  

Energy Technology Data Exchange (ETDEWEB)

The maintenance of a balance between cell gain and cell loss is essential for proper liver function. The exact role of aryl hydrocarbon receptor (AhR) in regulating cell proliferation and apoptosis of liver cells remains unclear, since ligand-dependent activation of AhR has been shown to induce cell cycle arrest, proliferation, differentiation or apoptosis, depending on the cellular model used. AhR can directly interact with retinoblastoma protein in hepatic cells, forming protein complexes that can efficiently block cell cycle progression by inducing G1 arrest, or to induce the expression of inhibitors of cyclin-dependent kinases, such as p271. On the other hand, it has been suggested that AhR could play a stimulatory role in cell proliferation, either directly or by mediating a release from contact inhibition. It is now generally accepted that progenitor cells exist in the liver, are activated in various liver diseases and can form a potential target cell ...

2004-09-15

256

Massage Therapy  

Medline Plus

... Massage therapy can help the body release certain chemicals. These chemicals help us relax, improve blood circulation and get ...

257

Laboratory evaluation of the feasibility of chemical oxidation processes for treatment of contaminated groundwaters. Final report  

Energy Technology Data Exchange (ETDEWEB)

Chemical oxidation is a treatment technology that uses powertul chemical oxidizers to destroy organic contaminants. Typical oxidizers used in chemical oxidation processes include ozone, hydrogen peroxide, chlorine, and potassium permanganate. The chemical reaction products are usually simple organic compounds, such as carboxylic acids, and/or inorganic compounds, such as carbon dioxide, water, and simple inorganic complexes (e.g., chloride salts, in the case of chemical oxidation treatment of chlorinated solvents).

1995-09-01

258

Coatings with controlled porosity and chemical properties  

Energy Technology Data Exchange (ETDEWEB)

Coatings and sensors having both steric and chemical selectivity. Controlled porosity provides the steric selectivity, whereas chemically tailored film properties, using controlled composition or modification by coupling agents, chemical species replacement, or chemical species within pores, provide the chemical selectivity. Single or multiple layers may be provided.

1996-01-01

259

U. S. Department of Energy project book  

Energy Technology Data Exchange (ETDEWEB)

This book covers representative projects in each program within the Department of Energy. The projects included were selected to provide an insight into the wide spectrum of projects authorized and under way in the Department. The projects described do not cover all projects authorized - they are merely representative. Descriptions, goals, and status are given for 29 energy projects, 4 scientific projects, and 5 defense projects. (RWR)

1980-01-01

260

Terpenoid-based defenses in conifers: cDNA cloning, characterization, and functional expression of wound-inducible (E)-?-bisabolene synthase from grand fir (Abies grandis)  

UK PubMed Central (United Kingdom)

(E)-α-Bisabolene synthase is one of two wound-inducible sesquiterpene synthases of grand fir (Abies grandis), and the olefin product of this cyclization reaction...Full Text Available

1998-06-09

261

Quality assurance plan for the Basic Environmental Compliance and Monitoring Program (BECAMP). Revision 1  

Energy Technology Data Exchange (ETDEWEB)

This quality assurance plan (QAP) is designed ensure that the methodologies and the data used for environmental cleanup and treatment studies at the Nevada Test Site are both usable and defensible. The QAP serves two purposes in this regard: (1) to guide the preparation of procedures for carrying out the tasks of the Basic Environmental compliance and Monitoring program (BECAMP); and (2) to help management track the progress of those tasks.

1993-11-01

262

Proceedings: Image Understanding Workshop  

Energy Technology Data Exchange (ETDEWEB)

Sponsored by the Defense Advanced Research Projects Agency the Image Understanding Workshop is a forum for the presentation of new research in vision, image analysis, and geometric modeling. Leading scientists present overviews of projects underway at major universities and corporate research sites, as well as results of individual work. The 1987 volume contains 94 articles and technical reports in two volumes.

1987-01-01

263

NI\\S/\\ - NASA Technical Reports Server  

Science.gov (United States)

The overall objective of this two phase NASA and Navy sponsored program ...... A tire pressure of 120 PSI and CBR of 5 to 6 is used to provide good soft field capability ...... DATCOM, the U. S. Air Force Stability and Control Handbook, is a .... goals were consistent with fleet air defense, attack capability, high ...

264

Malaria and other vector-borne infection surveillance in the U.S. Department of Defense Armed Forces Health Surveillance Center-Global Emerging Infections Surveillance program: review of 2009 accomplishments  

UK PubMed Central (United Kingdom)

Vector-borne infections (VBI) are defined as infectious diseases transmitted by the bite or mechanical transfer of arthropod vectors. They constitute a significant proportion of the global infectious...Full Text Available

265

Live Brucella spp. fail to induce tumor necrosis factor alpha excretion upon infection of U937-derived phagocytes.  

UK PubMed Central (United Kingdom)

Tumor necrosis factor alpha (TNF-alpha) plays a central role in activation of first-line defenses of a host against foreign organisms. To determine whether Brucella infection modulated TNF-alpha production,...Full Text Available

1994-12-01

266

Initial Evaluation of USAF Security Forces Distributed Mission Training (SecForDMT).  

Science.gov (United States)

United States Air Force security forces have a central role in force protection. Their missions include military police services, installation security, air base defense, military working dog functions, and combat arms training and maintenance. Surveys in...

2004-01-01

267

Downward penetration of hot UO/sub 2/ into basalt concrete  

Energy Technology Data Exchange (ETDEWEB)

Following a postulated meltdown accident, the integrity of containment building structural material under attack by hot molten core debris and the safeguard of environment against radiological releases constitutes the final line of defense in PAHR safety assessment. Such assessment requires a good knowledge of UO/sub 2//interaction and penetration with different types of concrete. The present study focuses on the phenomena associated with core debris interaction/penetration with substrate basalt concrete.

1983-01-01

268

Cold Vacuum Drying (CVD) Facility Technical Safety Requirements  

Energy Technology Data Exchange (ETDEWEB)

The Technical Safety Requirements (TSRs) for the Cold Vacuum Drying Facility define acceptable conditions, safe boundaries, bases thereof, and management or administrative controls required to ensure safe operation. Controls required for public safety, significant defense-in-depth, significant worker safety, and for maintaining radiological and toxicological consequences below risk evaluation guidelines are included.

1999-12-16

269

Aging and competence for physical defense among a-bomb survivors, 4. Determination of serum and urinary lysozyme (muramidase)  

Energy Technology Data Exchange (ETDEWEB)

Lysozyme activities of serum and urine in normal subjects, patients with various leukemias, and a-bomb survivors were determined. The lysozyme activity was increased in the majority of the leukemia patients. Urinary lysozyme of a-bomb survivors could not be detected.

1980-11-01

270

A submillimeter wavelength space-based imaging radar  

Science.gov (United States)

This report considers the use of a submillimeter wavelength space-based imaging radar. The main application envisioned is midcourse decoy discrimination for strategic defense, for which it would have the capability of producing a series of images, in real time, at strategic ranges, with less than meter scale resolution and with modest power requirements. Undoubtedly, there are other applications. The requirements for a SAR and ISAR imaging radar at submillimeter wavelength are determined, and the prospect for the development of RF sources to power the radar is examined.

1988-05-01

271

Genetic Modification of Short Rotation Poplar Biomass Feedstock for Efficient Conversion to Ethanol  

Energy Technology Data Exchange (ETDEWEB)

The Bioenergy Feedstock Development Program, Environmental Sciences Division, Oak Ridge National Laboratory is developing poplars (Populus species and hybrids) as sources of renewable energy, i.e., ethanol. Notable increases in adaptability, volume productivity, and pest/stress resistance have been achieved via classical selection and breeding and intensified cultural practices. Significant advances have also been made in the efficiencies of harvesting and handling systems. Given these and anticipated accomplishments, program leaders are considering shifting some attention to genetically modifying feedstock physical and chemical properties, so as to improve the efficiency with which feedstocks can be converted to ethanol. This report provides an in-depth review and synthesis of opportunities for and feasibilities of genetically modifying feedstock qualities via classical selection and breeding, marker-aided selection and breeding, and genetic transformation. ...

2000-08-30

272

The present status of astatine chemistry  

International Nuclear Information System (INIS)

24 isotopes of astatine element 85, are known today, three of which occur naturally as decay products of "2"1"5U and "2"5"8U, respectively. Because these isotopes being very short-lived, all experiments dealing with this heaviest element of the halogen group need be done with "2"0"9"-"2"1"1At, having half-lifes in the several hours region. Mixtures of them may be obtained either by #alpha#-bombardment (E#alpha# approximately 30-50 MeV) of "2"0"9Bi or as spallation products by the reaction of high-energy protons with thorium and uranium targets. - In its chemical reactions astatine shows a behaviour which is between an halogen and a metal. The following oxidation states have been shown to exist: -1, 0, +1, +5 and +7. At"-, AtO_2"- and AtO_4"- are the ionic species for At(-I), At(+V) and At(+VII) whereas no definite species have been established for the other oxidation states. Furthermore, At_2 could not be shown to exist as yet in contrast to ...

273

The advanced manufacturing science and technology program. FY 95 Annual Report  

Energy Technology Data Exchange (ETDEWEB)

This is the Fiscal Year 1995 Annual Report for the Advanced Manufacturing Science and Technology (AMST) sector of Los Alamos Tactical Goal 6, Industrial Partnering. During this past fiscal year, the AMST project leader formed a committee whose members represented the divisions and program offices with a manufacturing interest to examine the Laboratory`s expertise and needs in manufacturing. From a list of about two hundred interest areas, the committee selected nineteen of the most pressing needs for weapon manufacturing. Based upon Los Alamos mission requirements and the needs of the weapon manufacturing (Advanced Design and Production Technologies (ADaPT)) program plan and the other tactical goals, the committee selected four of the nineteen areas for strategic planning and possible industrial partnering. The areas selected were Casting Technology, Constitutive Modeling, Non-Destructive Testing and Evaluation, and Polymer Aging and Lifetime Prediction. For each area, the AMST ...

1996-03-01

274

Structures of trihydroxynaphthalene reductase-fungicide complexes: implications for structure-based design and catalysis  

Energy Technology Data Exchange (ETDEWEB)

Trihydroxynaphthalene reductase catalyzes two intermediate steps in the fungal melanin biosynthetic pathway. The enzyme, a typical short-chain dehydrogenase, is the biochemical target of three commercial fungicides. The fungicides bind preferentially to the NADPH form of the enzyme. Three X-ray structures of the Magnaporthe grisea enzyme complexed with NADPH and two commercial and one experimental fungicide were determined at 1.7 {angstrom} (pyroquilon), 2.0 {angstrom} (2,3-dihydro-4-nitro-1H-inden-1-one, 1), and 2.1 {angstrom} (phthalide) resolutions. The chemically distinct inhibitors occupy similar space within the enzyme's active site. The three inhibitors share hydrogen bonds with the side chain hydroxyls of Ser-164 and Tyr-178 via a carbonyl oxygen (pyroquilon and 1) or via a carbonyl oxygen and a ring oxygen (phthalide). Active site residues occupy similar positions among the three structures. A buried water molecule that is ...

2010-03-08

275

Status of lead and bismuth for radioimmunoimaging and radioimmunotherapy  

International Nuclear Information System (INIS)

Tumor-targeted monoclonal antibodies (mAb) might be useful as diagnostic or therapeutic agents when linked to cytotoxic or imaging reagents. Our group is working to test this hypothesis by linking cytocidal and image-producing isotopes to mAb and testing the utility of the radioimmunoconjugates formed in animal model systems. Radioiodines were first employed for these purposes,but unfavorable nuclear properties (half-lives, #gamma#-ray and #beta#-particle energies) and chemical reactivity (deiodination in vivo) limit their utility. Labeling immunoproteins with metallic radionuclides offers more versatility in that the selection of potentially useful radiometals spans the periodic table.Of the metallic radionuclides with physical properties most suited for use with mAb in nuclear medicine, few are more available or desirable than those of bismuth ("2"1"2Bi) and lead ("2"0"3Pb, "2"1"2Pb), as listed in Table 1. "2"1"2Bi or "2"1"2Pb could serve as ...

1990-08-26

276

Processing of La/sub 1. 8/Sr/sub 0. 2/CuO/sub 4/ and YBa/sub 2/Cu/sub 3/O/sub 7/ superconducting thin films by dual-ion-beam sputtering  

Science.gov (United States)

High quality La/sub 1.8/Sr/sub 0.2/CuO/sub 4/ and YBa/sub 2/Cu/sub 3/O/sub 7/ superconducting thin films, with zero resistance at 88 K, have been made by dual-ion-beam sputtering of metal and oxide targets at elevated temperatures. The films are about 1.0 ..mu..m thick and are single phase after annealing. The substrates investigated are Nd-YAP, MgO, SrF/sub 2/, Si, CaF/sub 2/, ZrO/sub 2/-9% Y/sub 2/O/sub 3/, BaF/sub 2/, Al/sub 2/O/sub 3/, and SrTiO/sub 3/. Characterization of the films was carried out using Rutherford backscattering spectroscopy, resistivity measurements, transmission electron microscopy, x-ray diffraction, and secondary ion mass spectroscopy. Substrate/film interaction was observed in every case. This generally involves diffusion of the substrate into the film, which is accompanied by, for example, the replacement of Ba by Sr in the YBa/sub 2/Cu/sub 2/O/sub 7/ structure, in the case of SrTiO/sub 3/ substrate. The best substrates were those that ...

1988-03-15

277

Mass spectrometric characterization of elements and molecules in cell cultures and tissues  

Energy Technology Data Exchange (ETDEWEB)

Time-of-flight secondary ion mass spectrometry (ToF-SIMS) and laser post-ionization secondary neutral mass spectrometry (laser-SNMS) have been used to image and quantify targeted compounds, intrinsic elements and molecules with subcellular resolution in single cells of both cell cultures and tissues. Special preparation procedures for analyzing cell cultures and tissue materials were developed. Cancer cells type MeWo, incubated with boronated compounds, were sandwiched between two substrates, cryofixed, freeze-fractured and freeze-dried. Also, after injection with boronated compounds, different types of mouse tissues were extracted, prepared on a special specimen carrier and plunged with high velocity into LN{sub 2}-cooled propane for cryofixation. After trimming, these tissue blocks were freeze-dried. The measurements of the K/Na ratio demonstrated that for both cell cultures and tissue materials the special preparation techniques used were appropriate for ...

2006-07-30

278

Instrumentation for monitoring and control of water chemistry for light-water-cooled nuclear power plants  

Energy Technology Data Exchange (ETDEWEB)

Based on the IAPWS technical guidance on ''Instrumentation for Monitoring and Control of Cycle Chemistry for Steam-Water Circuits of Fossil-Fired and Combined Cycle Power Plants,'' the latest situation regarding instrumentation for nuclear power plants is discussed. As a result of the discussion, it is concluded that: (1) Reliable and safe operation of plants is established by the application of suitable chemical conditions in plant cooling systems, which should be supported by the selection of suitable control targets for monitoring and by the application of reliable instruments. (2) The minimum level of key instrumentation consists of on-line as well as off-line instruments for monitoring the key parameters: - on-line: pH, conductivity, cation conductivity, O{sub 2} and H{sub 2} concentrations, electrochemical corrosion potential; - off-line: radioactive nuclides ({sup 60}Co, {sup 58}Co, {sup 131}I, etc.), ...

2010-05-15

279

Electromagnetic interactions in the {Delta}-resonance region  

Energy Technology Data Exchange (ETDEWEB)

Cross sections for some electro- and photoinduced spallation reactions on {sup 27}Al and {sup 51}V are measured in the energy region 130 MeV to 580 MeV with the activation method. Comparisons are made with calculations based on the Dalitz formalism for virtual photon spectra, and Monte Carlo calculations based on a cascade evaporation model, respectively. By use of Bremsstrahlung with end-point energies from threshold to 750 MeV, the yields for photo- production of{pi}{sup -}leading to ground and isomeric states in {sup 197}Hg are measured with the activation method. The activity from the Hg-isotopes were measured after a chemical separation of Hg from the target material. The yields and isomeric ratios are compared with impulse approximation calculations. For the photoproduction of {sup 195m}Hg and {sup 192}Hg from {sup 197}Au, the yields were measured. The experimental mean cross sections are compared with data from other experiments and with ...

1995-03-01

280

ERK-dependent and -independent pathways trigger human neural progenitor cell migration  

International Nuclear Information System (INIS)

Besides differentiation and apoptosis, cell migration is a basic process in brain development in which neural cells migrate several centimeters within the developing brain before reaching their proper positions and forming the right connections. For identifying signaling events that control neural migration and are therefore potential targets of chemicals to disturb normal brain development, we developed a human neurosphere-based migration assay based on normal human neural progenitor (NHNP) cells, in which the distance is measured that cells wander over time. Applying this assay, we investigated the role of the extracellular signal-regulated kinases 1 and 2 (ERK1/2) in the regulation of NHNP cell migration. Exposure to model substances like ethanol or phorbol 12-myristate 13-acetate (PMA) revealed a correlation between ERK1/2 activation and cell migration. The participation of phospho-(P-) ERK1/2 was confirmed by exposure of the cells to the ...

2007-05-15

281

Degradation of materials under conditions of the sulfur-iodine thermochemical cycle  

Energy Technology Data Exchange (ETDEWEB)

The sulfur-iodine (SI) thermochemical cycle is one of the main candidate methods to produce hydrogen from non-fossil sources like nuclear (GEN IV reactor) or solar thermal power. A major issue for the successful implementation of the SI cycle is the selection of technically viable and economic materials for construction of process components, particularly heat exchangers. Challenging conditions are encountered in each of the three sections of the SI cycle due to the corrosive chemicals present, including sulfuric acid, iodine, hydroiodic acid, sulfur dioxide, hydrogen, oxygen, and others. In Section I, aqueous, non-aqueous (liquid iodine), and gaseous multi-component phases are present at about 120 {sup o}C and 0.7 MPa. Section II involves gaseous and aqueous phases of sulfuric acid, sulfur dioxide, and oxygen at up to about 830 {sup o}C and 3.6 MPa. In Section III , aqueous, non-aqueous, and gaseous phases, at up to 310 {sup o}C and 2.2 MPa, containing iodine, ...

2009-07-01

282

Characterisation of thin films by phase modulated spectroscopic ellipsometry  

International Nuclear Information System (INIS)

A wide variety of thin film coatings, deposited by different techniques and with potential applications in various important areas, have been characterised by the Phase Modulated Spectroscopic Ellipsometer, installed recently in the Spectroscopy Division, B.A.R.C. The Phase Modulated technique provides a faster and more accurate data acquisition process than the conventional ellipsometry. The measured Ellipsometry spectra are fitted with theoretical spectra generated assuming an appropriate model regarding the sample. The fittings have been done objectively by minimising the squared difference (#chi#"2) between the measured and calculated values of the ellipsometric parameters and thus accurate information have been derived regarding the thickness and optical constants (viz, the refractive index and extinction coefficient) of the different layers, the surface roughness and the inhomogeneities present in the layers. Measurements have been done on (i) ion-implanted Si-wafers to ...

2009-12-01

283

Variation in the Definition of Clinical Target Volumes for Pelvic Nodal Conformal Radiation Therapy for Prostate Cancer  

UK PubMed Central (United Kingdom)

PurposeWe conducted a comparative study of Clinical Target Volume (CTV) definition of pelvic lymph nodes by multiple GU radiation oncologists looking at the levels...Full Text Available

2009-06-01

284

Targeted nanoparticles that deliver a sustained, specific release of paclitaxel to irradiated tumors  

UK PubMed Central (United Kingdom)

To capitalize on the response of tumor cells to ionizing radiation, we developed a controlled-release nanoparticle drug delivery system using a targeting peptide that recognizes a radiation-induced...Full Text Available

2010-06-01

285

Targeted Deletion of Somatotroph Insulin-Like Growth Factor-I Signaling in a Cell-Specific Knockout Mouse Model  

UK PubMed Central (United Kingdom)

The role of IGF-I in the negative regulation of GH expression and release is demonstrated by in vitro and in vivo models; however, the targets and mechanisms of IGF-I...Full Text Available

2010-05-01

286

Specific genetic modifications of domestic animals by gene targeting and animal cloning  

UK PubMed Central (United Kingdom)

The technology of gene targeting through homologous recombination has been extremely useful for elucidating gene functions in mice. The application of this technology was thought impossible in the large...Full Text Available

287

Selective imaging of adherent targeted ultrasound contrast agents  

UK PubMed Central (United Kingdom)

The goal of ultrasonic molecular imaging is the detection of targeted contrast agents bound to receptors on endothelial cells. We propose imaging methods that can distinguish adherent microbubbles...Full Text Available

2007-04-21

288

National Newborn Screening Status Reports  

Science.gov (United States)

... detected (and reported) as a by-product of MRM screening (MS/MS) targeted by Law or Rule ... detected (and reported) as a by-product of MRM screening (MS/MS) targeted by Law or Rule ...

289

Inhibitors of RecA Activity Discovered by High-Throughput Screening: Cell-Permeable Small Molecules Attenuate the SOS Response in Escherichia coli  

UK PubMed Central (United Kingdom)

The phenomenon of antibiotic resistance has created a need for the development of novel antibiotic classes with non-classical cellular targets. Unfortunately, target-based drug discovery against...Full Text Available

2009-10-01

290

How DNA coiling enhances target localization by proteins  

UK PubMed Central (United Kingdom)

Many genetic processes depend on proteins interacting with specific sequences on DNA. Despite the large excess of nonspecific DNA in the cell, proteins can locate their targets rapidly. After initial...Full Text Available

2008-10-14

291

Evolutionary conservation of a microbody targeting signal that targets proteins to peroxisomes, glyoxysomes, and glycosomes  

UK PubMed Central (United Kingdom)

Peroxisomes, glyoxysomes, glycosomes, and hydrogenosomes have each been classified as microbodies, i.e., subcellular organelles with an electron-dense matrix that is bound by a single membrane. We investigated...Full Text Available

1991-09-01

292

Efficient use of accessibility in microRNA target prediction  

UK PubMed Central (United Kingdom)

Considering accessibility of the 3′UTR is believed to increase the precision of microRNA target predictions. We show that, contrary to common belief, ranking by the hybridization energy or by...Full Text Available

2011-01-01

293

Coordination of PAD4 and HDAC2 in the regulation of p53 target gene expression  

UK PubMed Central (United Kingdom)

Histone Arg methylation and Lys acetylation have been found to cooperatively regulate the expression of p53 target genes. Peptidylarginine deiminase 4 (PAD4) is an enzyme that citrullinates...Full Text Available

2010-05-27

294

Concurrent schedule control of human visual target fixations1  

UK PubMed Central (United Kingdom)

Operant conditioning techniques were applied to the study of how target fixations are controlled by the probability of signal occurrence. In a standard vigilance setting, gaze at three illuminable...Full Text Available

1973-11-01

295

Biphasic targeting and cleavage furrow ingression directed by the tail of a myosin II  

UK PubMed Central (United Kingdom)

Cytokinesis in animal and fungal cells utilizes a contractile actomyosin ring (AMR). However, how myosin II is targeted to the division site and promotes AMR assembly, and how the AMR coordinates with...Full Text Available

2010-12-27

296

Assessment of nodal target definition and dosimetry using three different techniques: implications for re-defining the optimal pelvic field in endometrial cancer  

UK PubMed Central (United Kingdom)

Purposes1. To determine the optimal pelvic nodal clinical target volume for post-operative treatment of endometrial cancer. 2. To compare the DVH of different treatment planning...Full Text Available

297

Three-quasiparticle states in "1"7"7Ta  

International Nuclear Information System (INIS)

... transitions lutetium 175 target mev range 10-100 multipolarity neutrons parity

298

Terrorism Knowledge Base (TKB)  

Science.gov (United States)

... they assisted in the 2000 attack on the USS Cole? ... List the types of targets that ETA has attacked. ... was at least partially responsible for the attack. ...

2008-04-01

299

Surgical Counter-Terrorism: Targeting Individuals as an ...  

Science.gov (United States)

... Tanzania, and the attack on the USS COLE. ... vis another has no bearing on the legality of the attack. If the person attacked is a combatant, the use of ...

2003-02-03

300

Single-Walled Carbon Nanotubes Targeted to the Tumor ...  

Science.gov (United States)

... 1981. Retention of diphenyls, terphenyls, phenylalkanes and fluorene on graphitized thermal carbon black. Chromatographia 14:510-514. ...

2009-09-01

301

Review of Vaccinia Virus and Baculovirus Viability Versus ...  

Science.gov (United States)

... hazards. One study targeted the effects of common household disinfectants on virus inactivation (Butcher and Ulaeto, 2005). ...

2008-03-01

302

Production of polarized negative ion beams by collisional pumping  

Energy Technology Data Exchange (ETDEWEB)

The production of polarized negative ion beams by collisional pumping is described. Collisional pumping utilizes repeated charge changing collisions in a thick electron-spin-polarized gas or vapor target to form a polarized fast atom beam. The polarized fast atom beam is then partially converted into a polarized negative ion beam in a vapor target. Analysis is presented for a hydrogen beam passing through either a thick polarized H atom target or a thick polarized alkali target. Large polarizations and large currents may be possible.

1983-01-01

303

Production of polarized negative ion beams by ''collisional pumping''  

Energy Technology Data Exchange (ETDEWEB)

The production of polarized negative ion beams by ''collisional pumping'' is described. Collisional pumping utilizes repeated charge changing collisions in a thick electron-spin-polarized gas or vapor target to form a polarized fast atom beam. The polarized fast atom beam is then partially converted into a polarized negative ion beam in a vapor target. Analysis is presented for a hydrogen beam passing through either a thick polarized H atom target or a thick polarized alkali target. Large polarizations and large currents may be possible.

1984-03-01

305

Pairing effect in the nucleon transfer processes in quasi-elastic heavy ion scattering  

International Nuclear Information System (INIS)

... range krypton 86 reactions molybdenum 92 target probability quasi-elastic

1987-04-14

306

Market segmentation and targeting for real time pricing  

Energy Technology Data Exchange (ETDEWEB)

While there is growing interest in Real Time Pricing as a competitive tool, its adoption to date has been constrained by wariness on the part of many utilities and many of their customers. That wariness is not misplaced, for Real Time Pricing is not for everyone. In order for both utilities and their customers to benefit, the pricing system must be properly tailored for, and offered to, the appropriate audience. This paper discusses needs for identifying targets, implications of targeting of Real Time Pricing to various types of customers, and implications for design and marketing of such pricing systems. Examples from utility experiences are provided, and recommendations are offered for development of improved targeting of Real Time Pricing.

1996-03-01

307

Fragmentation of nuclei by particles and nuclei of intermediate and high energies  

Energy Technology Data Exchange (ETDEWEB)

The present state of investigations into the fragmentation of target nuclei by particles and nuclei of intermediate and high energies is reviewed.

1983-11-01

309

Electron-Induced Luminescence and X-Ray Spectrometer (ELXS) System for Life Detection  

Science.gov (United States)

The ELXS concept is a novel, portable, micro-instrument targeted for the detection of mineralogic

2002-01-01

310

Electromagnetic excitations in nuclei: From photon scattering to photo-dissociation  

International Nuclear Information System (INIS)

... 98 target molybdenum 99 niobium 91 photoneutrons photonuclear reactions

2006-03-20

311

Effect of improved target designs on the "2"3"8Pu production at the Fast Flux Test Reactor  

International Nuclear Information System (INIS)

This paper present the results of a series of calculations made to determine the "2"3"8Pu production potential of several advanced target assembly designs in the Fast Flux Test Facility (FFTF). These calculations show that by using advanced target designs the intimately mix the "2"3"7Np target material with an yttrium hydride moderator, the FFTF has the potential of producing up to 30 kg of high-quality "2"3"8Pu per year.

1991-11-10

312

Target space duality II: applications  

Energy Technology Data Exchange (ETDEWEB)

We apply the framework developed in Target space duality I: general theory. We show that both nonabelian duality and Poisson-Lie duality are examples of the general theory. We propose how the formalism leads to a systematic study of duality by studying few scenarios that lead to open questions in the theory of Lie algebras. We present evidence that there are probably new examples of irreducible target space duality.

2000-09-25

313

Gastrin releasing peptide (GRP) receptor targeted radiopharmaceuticals: A concise update  

Energy Technology Data Exchange (ETDEWEB)

The gastrin releasing peptide (GRP) receptor is becoming an increasingly attractive target for development of new radiolabeled peptides with diagnostic and therapeutic potential. The attractiveness of the GRP receptor as a target is based upon the functional expression of GRP receptors in several tumors of neuroendocrine origin including prostate, breast, and small cell lung cancer. This concise review outlines some of the efforts currently underway to develop new GRP receptor specific radiopharmaceuticals by employing a variety of radiometal chelation systems.

2003-11-01

314

Effluent reduction using pinch technology: Targets for reduction and capital costs for mass exchange networks  

Energy Technology Data Exchange (ETDEWEB)

This paper illustrates how the techniques developed by the authors for capital cost targeting of mass exchange networks can be applied to determination of capital investment targets for reduction in effluent for existing systems involving mass exchange. The results is an impact diagram which shows the relationship between effluent reduction and capital investment, indicating a region of limiting return on investment as well as the maximum possible reduction in effluent. (au)

1999-02-01

315

Development of a new secondary beam separator and a new gas-jet target at Kyushu University  

International Nuclear Information System (INIS)

In order to facilitate observations of low energy nuclear reactions, a new type recoil mass-separator together with a new gas-jet target system is being developed at the tandem accelerator facility in Kyushu University. The expected mass-resolving power of the separator is 220 for a solid angle of 10 msr and the practical thickness of the gas-jet target will exceed 0.1 atm#centre dot#cm for the light elements of H and He. (author).

1994-06-01

316

A Liquid Parahydrogen Target for the Measurement of a Parity-violating Gamma Asymmetry in Polarized Neutron Capture on Protons  

Energy Technology Data Exchange (ETDEWEB)

A 16 l liquid parahydrogen target has been developed for a measurement of the parity-violating {gamma}-asymmetry in the capture of polarized cold neutrons on protons in the {rvec n} + p {yields} d + {gamma} reaction by the NPDGamma collaboration. The target system was carefully designed to meet the stringent requirements on systematic effects for the experiment and also to satisfy hydrogen safety requirements. The target was designed to preserve the neutron polarization during neutron scattering on liquid hydrogen (LH{sub 2}), optimize the statistical sensitivity to the {rvec n} + p {yields} d + {gamma} reaction, minimize backgrounds coming from neutron interaction with the beam windows of the target cryostat, minimize LH{sub 2} density fluctuations which can introduce extra noise in the gamma asymmetry signal, and control systematic effects. The target incorporates two mechanical ...

2010-05-01

317

48 CFR 952.226-73 - Energy Policy Act target group certification.  

Science.gov (United States)

...2010-10-01 2010-10-01 false Energy Policy Act target group certification...Acquisition Regulations System DEPARTMENT OF ENERGY CLAUSES AND FORMS SOLICITATION...Provisions and Clauses 952.226-73 Energy Policy Act target group...

2010-10-01

318

Selection of IFE target materials from a safety and environmental perspective  

International Nuclear Information System (INIS)

Target materials for inertial fusion energy (IFE) power plant designs might be selected for a wide variety of reasons including wall absorption of driver energy, material opacity, cost and ease of fabrication. While each of these issues are of great importance, target materials should also be selected based upon their safety and environmental (S and E) characteristics. The present work focuses on the recycling, waste management and accident dose characteristics of potential target materials. If target materials are recycled so that the quantity is small, isotopic separation may be economically viable. Therefore, calculations have been completed for all stable isotopes for all elements from lithium to polonium. The results of these calculations are used to identify specific isotopes and elements that are most likely to be offensive as well as those most likely to be acceptable in terms of their S and E ...

2001-05-21

319

Mode of action of membrane-disruptive lytic compounds from the marine dinoflagellate Alexandrium tamarense  

British Library Electronic Table of Contents (United Kingdom)

Certain allelochemicals of the marine dinoflagellate Alexandrium tamarense cause lysis of a broad spectrum of target protist cells but the lytic mechanism is poorly defined. We first hypothesized that membrane sterols serve as molecular targets of these lytic compounds, and that differences in sterol composition among donor and target cells may cause insensitivity of Alexandrium and sensitivity of targets to lytic compounds. We investigated Ca^2^+ influx after application of lytic fractions to a model cell line PC12 derived from a pheochromocytoma of the rat adrenal medulla to establish how the lytic compounds affect ion flux associated with lysis of target membranes. The lytic compounds increased permeability of the cell membrane for Ca^2^+ ions even during blockade of Ca^2^+ channels wit...

2011-01-01

320

An identification method of positron production in laser beam interaction with targets  

Energy Technology Data Exchange (ETDEWEB)

A simple electromagnetic transport system was constructed to identify very rare positrons produced in a powerful laser beam interaction with a target. Testing experiments were carried out with CO[sub 2]-laser (10[sup 12] W/cm[sup 2]) beam pulses ([tau] = 50 ns, f = 0.01 Hz) focused on the copper target, as well as with a 96 MeV alpha-particle beam irradiated carbon target. The results showed that the developed system could be effectively used for positron identification and evaluation of their energy by means of a time-of-flight method. The computerized system to deal with this problem, together with others related to the power laser beam interaction with targets, has been constructed. (orig.).

1992-10-01

321

Activation analysis of target debris in the national ignition facility  

International Nuclear Information System (INIS)

The modeling methods used to compute the neutron-induced activation of target and near-target materials in the NIF facility are presented. A detailed space and energy description of the neutron environment in the different materials is provided. A new capability has been developed to treat in a general way the activation of debris produced in an operational regime of yield and no-yield experiments. First calculations are addressed to analyze the activity of the debris into the target chamber. The contribution of the different components to activity, interior dose rates, and waste disposal rating (WDR) is determined. The importance of the activation coming from primary irradiation in the target, and from secondary irradiation in debris deposited onto the first wall is assessed. Finally, waste hazards of the activated debris when removed out of the chamber and stored are analyzed. (authors)

1999-09-12

322

Star-formation triggers and chemical evolution  

Energy Technology Data Exchange (ETDEWEB)

Comparative studies of flocculent and grand-design spirals suggest that density waves are not the predominant trigger of star formation in most galaxies. Implications for chemical evolution are profound. It may be possible to ignore the details of the spiral-wave phenomenon in research aimed at unifying the chemical properties of spiral disks. 16 references.

1986-10-01

323

Low-Level Exposure to Multiple Chemicals: Reason for Human Health Concerns?  

UK PubMed Central (United Kingdom)

BackgroundA key question in the risk assessment of exposures to multiple chemicals is whether mixture effects may occur when chemicals are combined at low doses which individually...Full Text Available

2007-12-01

324

Interactive Toxicity of Inorganic Mercury and Trichloroethylene in Rat and Human Proximal Tubules  

UK PubMed Central (United Kingdom)

Simultaneous or prior exposure to one chemical may alter the concurrent or subsequent response to another chemical, often in unexpected ways. This is particularly true when the two chemicals...Full Text Available

2007-06-15

325

Identification of environmental chemicals with estrogenic activity using a combination of in vitro assays.  

UK PubMed Central (United Kingdom)

Environmental chemicals that function as estrogens have been suggested to be associated with an increase in disease and dysfunctions in animals and humans. To characterize chemicals that may act as...Full Text Available

1996-10-01

326

Chemical activation of MEK1 - a redox trigger for evaluating the effects of phosphorylation.  

Science.gov (United States)

An approach to generate mimics of phosphorylated serine proteins chemically through site-specific sulfonation of cysteine is presented. This chemical modification is reversible in the presence of reducing agent and therefore is analogous to the kinase/phosphatase system used in nature. PMID:21717004

2011-06-30

327

Absence of morphologic correlation between chemical toxicity and chemical carcinogenesis.  

UK PubMed Central (United Kingdom)

The experimental data set used to evaluate site-specific histopathologic correspondence between the morphologic end points of toxicity and carcinogenicity comprises 130 chemical carcinogenesis studies....Full Text Available

1993-12-01

328

Quality assurance requirements for high-level waste form production  

International Nuclear Information System (INIS)

The US Department of Energy (DOE) Defense Waste Management Plan has the objective of final disposal for high-level waste (HLW) generated from defense programs. The DOE sites that generate HLW are located at the Savannah River Operations Office in Aiken, South Carolina, the Hanford site in Richland, Washington, and the Idaho Operations Office in Idaho Falls, Idaho. The purpose in the development of a quality assurance (QA) specification for organizations involved in HLW production is to establish uniform requirements that ensure that radioactive waste is converted to a waste form and canistered in such a way that it is acceptable in a federal repository licensed by the US Nuclear Regulatory Commission (NRC). A QA specification has been developed that will be applied to those activities important to certification of the product. The basic requirements are defined in national consensus standards and DOE directives. The supplemental requirements ...

1988-06-12

329

Joint Integration Office Independent Review Committee annual report, 1985  

Energy Technology Data Exchange (ETDEWEB)

Comprised of seven persons with extensive experience in the issues of nuclear waste, the Independent Review Committee (IRC) provides independent and objective review of Defense Transuranic Waste Program (DTWP) activities managed by the Joint Integration Office (JIO), formerly the Defense Transuranic Waste Lead Organization (TLO). The Committee is ensured a broad, interdisciplinary perspective since its membership includes representatives from the fields of nuclear engineering, nuclear waste transportation, industrial quality control, systems and environmental engineering and state and local government. The scope of IRC activities includes overall review of specific TLO plans, projects and activities, and technical review of particular research and development projects. The Committee makes specific suggestions and recommendations based upon expertise in the field of TRU Waste Management. The IRC operates as a consulting group, under an ...

1986-08-01

330

Defense Threat Reduction Agency Radiochemical Needs  

International Nuclear Information System (INIS)

The United States Government (USG) first developed nuclear forensics-related capabilities to analyze radiological and nuclear materials, including underground nuclear test debris and interdicted materials. Nuclear forensics is not a new mission for Department of Defense (DoD). The department's existing nuclear forensics capability is the result of programs that span six (6) decades and includes activities to assess foreign nuclear weapons testing activities, monitor and verify nuclear arms control treaties, and to support intelligence and law enforcement activities. Today, nuclear forensics must support not only weapons programs and nuclear smuggling incidents, but also the scientific analysis and subsequent attribution of terrorists' use of radiological or nuclear materials/devices. Nuclear forensics can help divulge the source of origin of nuclear materials, the type of design for an interdicted or detonated device, as well as the pathway of the materials or ...

2009-08-19

331

Cryocycling of energetic materials: Status report for FY94  

Energy Technology Data Exchange (ETDEWEB)

The Cryocycling of Energetic Materials Project is sponsored by the Memorandum of Understanding (MOU) on advanced munition technologies. This MOU is an agreement between the Department of Energy and the Department of Defense (Office of Munitions) that facilitates the development of technologies of mutual interest to the two Departments. The cryocycling project is one of several that focus on demilitarization aspects of conventional weapons and weapon systems. During FY94 the project pursued the development of analytical and numerical models that can be used to describe and optimize the cryocycling process for preparing energetic materials for recycle and reuse. In addition, the demilitarization stockpile of the Department of Defense was analyzed to identify candidate munitions for the process, and pilot scale cryocycling operations were begun at an industrial contractor. When a material is cryocycled, it is repeatedly subjected to cycles of ...

1995-07-01

332

Accelerator driven assembly  

Energy Technology Data Exchange (ETDEWEB)

This report addresses a Los Alamos National Laboratory (LANL) proposal to build a pulsed neutron source for simulating nuclear-weapons effects. A point design for the pulsed neutron facility was initiated early in FY94 after hosting a Defense Nuclear Agency (DNA) panel review and after subsequently visiting several potential clients and users. The technical and facility designs contained herein fulfill the Statement of Work (SOW) agreed upon by LANL and DNA. However, our point designs and parametric studies identify a unique, cost-effective, above-ground capability for neutron nuclear-weapons-effects studies at threat levels. This capability builds on existing capital installations and infrastructure at LANL. We believe that it is appropriate for us, together with the DNA, to return to the user community and ask for their comments and critiques. We also realize that the requirements of last year have changed significantly. Therefore, the present report is a ...

1997-01-01

333

Waste Management Project fiscal year 1998 multi-year work plan, WBS 1.2  

Energy Technology Data Exchange (ETDEWEB)

The Waste Management Project manages and integrates (non-TWRS) waste management activities at the site. Activities include management of Hanford wastes as well as waste transferred to Hanford from other DOE, Department of Defense, or other facilities. This work includes handling, treatment, storage, and disposal of radioactive, nonradioactive, hazardous, and mixed solid and liquid wastes. Major Waste Management Projects are the Solid Waste Project, Liquid Effluents Project, and Analytical Services. Existing facilities (e.g., grout vaults and canyons) shall be evaluated for reuse for these purposes to the maximum extent possible.

1997-09-23

334

Veterinary care of the Belgian Malinois military working dog.  

Science.gov (United States)

The Belgian Malinois dog was introduced into the Department of Defense Military Working Dog Program in 1984. All dogs are purchased in Europe and have adapted well to the rigorous training requirements of the program. Most veterinary problems seen in this breed are related to kennel confinement and include traumatic dental disease, tail lesions, a variety of dermatologic conditions, and an inability to gain weight. Epilepsy is a breed problem and has been seen in this population, as has gastric dilatation/volvulus. Both elbow and hip dysplasia exist in the Malinois breed. PMID:1900116

1991-01-01

335

U.S. Government Capabilities to Support Analysis of Gamma Ray Data Submitted by Field Elements  

Energy Technology Data Exchange (ETDEWEB)

As radiation detection in the interest of national security becomes increasingly commonplace, inevitable questions arise concerning the interpretation of data from handheld radioisotope identifiers (RIIDs). Field elements typically require fast answers to provide an effective defense and to minimize the impact on legitimate movement of people and goods. To support this need, on-call experts at Sandia, Los Alamos, and Lawrence Livermore national laboratories cooperate in resolving radiation alarms rapidly and accurately. We present an overview, describe the work in progress to improve capabilities, and report on some of the lessons learned.

2005-07-07

336

Transmission electron microscopy of simulated DWPF high level nuclear waste glasses following gamma irradiation  

International Nuclear Information System (INIS)

Thermal analysis testing revealed slight weight changes, which were a function of gamma irradiation, in a highly reduced Defense Waste Processing Facility (DWPF) simulated waste glass. Transmission electron microscopy (TEM) was performed on this glass to determine if the weight change corresponded to microstructural variations. TEM analyses showed that no microstructural changes were attributable to gamma irradiation. Exposure of the samples to the electron beam in the TEM did cause changes in the glass microstructures in some cases. These changes were likely due to localized heating of the glass due to interactions with the transmitted electrons.

1994-04-25

337

Oral histories at the Hanford Nuclear Reservation  

Energy Technology Data Exchange (ETDEWEB)

The founding of the Hanford Engineering Works to produce plutonium is described. The 45-year defense mission has now been replaced with a peaceful mission, that of being the first site for massive cleanup of the 45-year nuclear waste. In order to establish a remedial investigation and feasibility plan, a process of discovery named the Technical Baseline Report must be performed; the task of this process is to discover all that is known about a proposed cleanup site (what the waste was, where did it go). When none of the documentation can answer the question, oral history is utilized. Some of the problems associated with the conduct of oral history interviews are described, particularly Hanford`s legacy of secrecy.

1992-03-01

338

Net-centric information management challenges  

Science.gov (United States)

The Department of Defense is making significant investments to construct systems, built upon web services and their supporting technologies, that strive to achieve the goals of net-centricity. While these technologies address several of the traditional stumbling blocks to integration and interoperability, they leave issues of information management largely unaddressed. Indeed, the broad availability of these systems exacerbates, rather than reduces, stresses on our information management capabilities. This paper discusses the enterprise-level information management infrastructure objectives for providing net-centric military capabilities and more fundamental technical challenges derived from them.

2005-05-01

339

Melter system technology testing for Hanford Site low-level tankwaste vitrification  

Energy Technology Data Exchange (ETDEWEB)

Following revisions to the Tri-Party Agreement for Hanford Site cleanup, which specified vitrification for Complete melter feasibility and system operability immobilization of the low-level waste (LLW) tests, select reference melter(s), and establish reference derived from retrieval and pretreatment of the radioactive LLW glass formulation that meets complete systems defense wastes stored in 177 underground tanks, commercial requirements (June 1996). Available melter technologies were tested during 1994 to 1995 as part of a multiphase program to select reference Submit conceptual design and initiate definitive design technologies for the new LLW vitrification mission.

1996-05-03

340

Immunity and tolerance to infections in experimental hematopoietic transplantation  

British Library Electronic Table of Contents (United Kingdom)

Resistance and tolerance are two types of host defense mechanisms that increase fitness in response to fungi. Several genetic polymorphisms in pattern recognition receptors, most remarkably Toll-like receptors (TLRs), have been described to influence resistance and tolerance to aspergillosis in distinct clinical settings. TLRs on dendritic cells pivotally contribute in determining the balance between immunopathology and protective immunity to the fungus. Epithelial cells also contribute to this balance via selected TLRs converging on indoleamine-2,3-dioxygenase (IDO). Studies in experimental hematopoietic transplantation confirmed the dichotomy of pathways leading to resistance and tolerance to the fungus providing new insights on the relative contribution of the hematopoietic/nonhematopoi...

2011-01-01

341

Gross anatomy of network security  

Science.gov (United States)

Information security involves many branches of effort, including information assurance, host level security, physical security, and network security. Computer network security methods and implementations are given a top-down description to permit a medically focused audience to anchor this information to their daily practice. The depth of detail of network functionality and security measures, like that of the study of human anatomy, can be highly involved. Presented at the level of major gross anatomical systems, this paper will focus on network backbone implementation and perimeter defenses, then diagnostic tools, and finally the user practices (the human element). Physical security measures, though significant, have been defined as beyond the scope of this presentation.

2002-01-01

342

Energy and technology review  

Energy Technology Data Exchange (ETDEWEB)

The state of the laboratory address by LLNL Director Roger Batzel is summarized, and a breakdown of the laboratory funding is given. The Livermore defense-related committment is described, including the design and development of advanced nuclear weapons as well as research in inertial confinement fusion, nonnuclear ordnance, and particle beam technology. LLNL is also applying its scientific and engineering resources to the dual challenge of meeting future energy needs without degrading the quality of the biosphere. Some representative examples are given of the supporting groups vital for providing the specialized expertise and new technologies required by the laboratory's major research programs. (GHT)

1982-07-01

343

Development of safety function assessment trees for pressurized heavy water reactor LP/SD operations  

Energy Technology Data Exchange (ETDEWEB)

The objective of Configuration Risk Management Program(CRMP) is to maintain the safety level by assuring the defense-in-depth of nuclear power plant while the configurations are changed during plant operations, especially for the LP/SD. Such a safety purpose can be achieved by establishing the risk monitoring programs with both quantitative and qualitative features. Generally, the quantitative risk evaluation models, i.e., PRA models are used for the risk evaluation during full power operation, and the qualitative risk evaluation models such as safety function assessment trees are used. Through this study, safety function assessment trees were developed.

2003-10-01

344

DARPA Fact File: A Compendium of DARPA Programs  

Science.gov (United States)

In April 2002, the Defense Advanced Research Projects Agency (DARPA) released this overview of its current work. The report summarizes many of the organization's main programs, which are grouped into three broad areas. The first area details the efforts being made to minimize threats and ensure national security. Development of new technologies and advanced systems is highlighted in the second section, and the third looks at investigations into "high-risk, high-payoff technologies." There are numerous references to the war on terrorism that describe DARPA's involvement and specific projects to defend against terrorist acts.

2002-01-01

345

[Improvement of the recognition probability about camouflage target based on BP neural network].  

Science.gov (United States)

Using static Michelson interferometer to get the spectrum information of measurement targets for spectrum identification, under the condition that the interference length is constant, the system can be optimized by BP neural network algorithm for the mixed spectral separation process. Thereby it can realize improving the recognition probability of camouflage target. Collecting the spectrum information in field of view (FOV) by the interferometer and linear array CCD detector, composing the set of mixed spectrum data, with known absorption spectrum of the material as a hidden layer of rules, it used BP neural network to separate the mixed spectrum data. Experiment with different distances, different combinations of mixed background spectrum as the initial data, using steel target (size: 1.5 m x 1.5 m) made of four kinds, the recognition probability of non-camouflage target is about 90% by BP neural ...

2010-12-01

346

Traffic and transport in the Dutch National Environmental Outlook 4; Verkeer en vervoer in de Nationale Milieuverkenning 4  

Energy Technology Data Exchange (ETDEWEB)

In the Fourth Dutch National Environmental Outlook (NMP, abbreviated in Dutch) of the National Institute of Public Health and the Environment (VROM), published in July 1997, possible future developments in the traffic and transport sector in the Netherlands are described for the period 1995-2020 and also evaluates present Dutch policies. NMP-4 also offers possible solutions for expected environmental problems. This report serves as a background document for the traffic and transport sector. With a view to present Dutch policies, the main conclusions drawn from the Outlook are that: (1) the policy targets for car and lorry use for 2010 will not be met, (2) the target for CO2 emissions from road transport for 2010 will not be met, (3) the NOx emission target for 2010 will be met for cars, but not for trucks, (4) the VOC emission target for 2010 will be met for cars, but not for trucks, and (5) the noise ...

1998-03-01

347

Impacts on Competitiveness from EU ETS. An analysis of the Dutch Industry  

Energy Technology Data Exchange (ETDEWEB)

The EU emissions trading scheme (ETS) was launched in 2005 to cap CO2 emissions from large industrial facilities and electricity producers. The European Commission is currently designing the post 2012 EU ETS, as outlined in COM(2008)16. Novel to this system is that a greater part of the rights will be auctioned. Auctioning in general assures a greater deal of efficiency compared to (certain types of) free allocation, lowers the administrative costs and prevents eventual windfall profits. However, auctioning also implies a potential loss of competitiveness for industry. If no international agreement on future climate policies is reached, firms may not be able to pass on the higher costs to their customers and may be faced with a loss in profitability and the threat of import substitution. In any emission trading scheme with an absolute cap, a relocation of production that is not covered by CO2 targets implies an increase in global CO2 emissions. This phenomenon has ...

2008-01-15

348

Molecular Genetics and Carcinogenesis Section  

Science.gov (United States)

The Molecular Genetics and Carcinogenesis Section conducts studies using human epithelial cells to assess: activation of proto-oncogenes by chemical and physical carcinogens; inactivation and dysregulation of tumor suppressor genes by chemical and physical

349

Hard Corrosion and Radiation-Resistant Coatings  

International Science & Technology Center (ISTC)

Hard Nano-Strutural Coatings Resistant to the Extreme Conditions of Chemical, Abrasive and High Energy Media for Thermonuclear Power, Oil and Gas and Chemical Industries

350

Environmental chemical-induced macrophage dysfunction.  

UK PubMed Central (United Kingdom)

Immunomodulation by environmental chemical contaminants and the role immune parameters play in toxicity and risk assessment studies is of increasing concern. Although considerable evidence has indicated...Full Text Available

1981-06-01

351

Chemical Carcinogenesis Testing and Related Issues ...  

Science.gov (United States)

... 6 lit. CHEMICAL CARCINOGENESIS TESTING AND RELATED ISSUES- ILn SUBCHRONIC STUDIES AND RELATED ISSUES 0 o Andrew Sivak 0 ...

1985-05-01

352

Atmospheric chemistry in volcanic plumes  

UK PubMed Central (United Kingdom)

Recent field observations have shown that the atmospheric plumes of quiescently degassing volcanoes are chemically very active, pointing to the role of chemical cycles involving halogen species and...Full Text Available

2010-04-13

353

Application of Key Events Analysis to Chemical Carcinogens and Noncarcinogens  

UK PubMed Central (United Kingdom)

The existence of thresholds for toxicants is a matter of debate in chemical risk assessment and regulation. Current risk assessment methods are based on the assumption that, in the absence of sufficient...Full Text Available

2009-09-01

354

Review of the WIPP draft application to show compliance with EPA transuranic waste disposal standards  

Energy Technology Data Exchange (ETDEWEB)

The purpose of the New Mexico Environmental Evaluation Group (EEG) is to conduct an independent technical evaluation of the Waste Isolation Pilot Plant (WIPP) Project to ensure the protection of the public health and safety and the environment. The WIPP Project, located in southeastern New Mexico, is being constructed as a repository for the disposal of transuranic (TRU) radioactive wastes generated by the national defense programs. The EEG was established in 1978 with funds provided by the U.S. Department of Energy (DOE) to the State of New Mexico. Public Law 100-456, the National Defense Authorization Act, Fiscal Year 1989, Section 1433, assigned EEG to the New Mexico Institute of Mining and Technology and continued the original contract DE-AC04-79AL10752 through DOE contract DE-AC04-89AL58309. The National Defense Authorization Act for Fiscal Year 1994, Public Law 103-160, continues the authorization. EEG performs ...

1996-03-01

355

Final Scientific EFNUDAT Workshop  

ScienceCinema

...and it's really a pleasure to ...you and ...and for ...was shelled and then doses of pleasure for me to ...and my director general ...? and journal article ? ...but and yeah well that's um ? ...and ...and what could be achieved ? what might be the consequences ...? and ...and ...and ...and ...and ...structural because and ...over and hopefully is also serve the purpose to get ...principles and ...and ...and ...how to use them and future ...and and that ...and purposes and that's very important ...you and ...and ...and in the future ? and yeah ...true and ...and ...just and and and and and the order of nuclear physics a ...useful and ...too much ? and ...portable comes from and ...and ...and ...and ...no more ? how to knowledge and the and ...and ...and and keep ever seen all of all ? ...and ...and ...and what you're ...and ...and ...and you and ...and ...and ...and so when you keep that and and ...and ...? and ...and ...and ...the problems and the other side ? ...door and a ...and ...

356

Is uniform target dose possible in IMRT plans in the head and neck?  

International Nuclear Information System (INIS)

Purpose: Various published reports involving intensity-modulated radiotherapy (IMRT) plans developed using automated optimization (inverse planning) have demonstrated highly conformal plans. These reported conformal IMRT plans involve significant target dose inhomogeneity, including both overdosage and underdosage within the target volume. In this study, we demonstrate the development of optimized beamlet IMRT plans that satisfy rigorous dose homogeneity requirements for all target volumes (e.g., #+-#5%), while also sparing the parotids and other normal structures. Methods and Materials: The treatment plans of 15 patients with oropharyngeal cancer who were previously treated with forward-planned multisegmental IMRT were planned again using an automated optimization system developed in-house. The optimization system allows for variable sized beamlets computed using a three-dimensional convolution/superposition dose ...

2002-04-01

357

WASTE SOLIDIFICATION BUILDING BENCH SCALE HIGH ACTIVITY WASTE SIMULANT VARIABILITY STUDY FY2008  

Energy Technology Data Exchange (ETDEWEB)

The primary objective of this task was to perform a variability study of the high activity waste (HAW) acidic feed to determine the impact of feed variability on the quality of the final grout and on the mixability of the salt solution into the dry powders. The HAW acidic feeds were processed through the neutralization/pH process, targeting a final pH of 12. These fluids were then blended with the dry materials to make the final waste forms. A secondary objective was to determine if elemental substitution for cost prohibitive or toxic elements in the simulant affects the mixing response, thus providing a more economical simulant for use in full scale tests. Though not an objective, the HAW simulant used in the full scale tests was also tested and compared to the results from this task. A statistically designed test matrix was developed based on the maximum molarity inputs used to make the acidic solutions. The maximum molarity inputs were: 7.39 HNO{sub 3}, 0.11618 ...

2009-03-20

358

REQUIREMENTS AND GUIDELINES FOR NSLS EXPERIMENTAL BEAM LINE VACUUM SYSTEMS-REVISION B.  

Energy Technology Data Exchange (ETDEWEB)

Typical beam lines are comprised of an assembly of vacuum valves and shutters referred to as a ''front end'', optical elements to monochromatize, focus and split the photon beam, and an experimental area where a target sample is placed into the photon beam and data from the interaction is detected and recorded. Windows are used to separate sections of beam lines that are not compatible with storage ring ultra high vacuum. Some experimental beam lines share a common vacuum with storage rings. Sections of beam lines are only allowed to vent up to atmospheric pressure using pure nitrogen gas after a vacuum barrier is established to protect ring vacuum. The front end may only be bled up when there is no current in the machine. This is especially true on the VUV storage ring where for most experiments, windows are not used. For the shorter wavelength, more energetic photons of the x-ray ring, beryllium windows are used at various beam ...

1999-05-01

359

Predicted versus observed cosmic-ray-produced noble gases in lunar samples: improved Kr production ratios. [From excitation functions for proton spallation of Rb, Sr, Y, Zr at 10 MeV to 10 GeV  

Science.gov (United States)

New sets of cross sections for the production of krypton isotopes from targets of Rb, Sr, Y, and Zr were constructed primarily on the bases of experimental excitation functions for Kr production from Y. These cross sections were used to calculate galactic-cosmic-ray and solar-proton production rates for Kr isotopes in the moon. Spallation Kr data obtained from ilmenite separates of rocks 10017 and 10047 are reported. Production rates and isotopic ratios for cosmogenic Kr observed in ten well-documented lunar samples and in ilmenite separates and bulk samples from several lunar rocks with long but unknown irradiation histories were compared with predicted rates and ratios. The agreements were generally quite good. Erosion of rock surfaces affected rates or ratios for only near-surface samples, where solar-proton production is important. There were considerable spreads in predicted-to-observed production rates of /sup 83/Kr, due at least in part to uncertainties in ...

1979-01-01

360

Development of a Novel Efficient Solid-Oxide Hybrid for Co-generation of Hydrogen and Electricity Using Nearby Resources for Local Application  

Energy Technology Data Exchange (ETDEWEB)

Developing safe, reliable, cost-effective, and efficient hydrogen-electricity co-generation systems is an important step in the quest for national energy security and minimized reliance on foreign oil. This project aimed to, through materials research, develop a cost-effective advanced technology cogenerating hydrogen and electricity directly from distributed natural gas and/or coal-derived fuels. This advanced technology was built upon a novel hybrid module composed of solid-oxide fuel-assisted electrolysis cells (SOFECs) and solid-oxide fuel cells (SOFCs), both of which were in planar, anode-supported designs. A SOFEC is an electrochemical device, in which an oxidizable fuel and steam are fed to the anode and cathode, respectively. Steam on the cathode is split into oxygen ions that are transported through an oxygen ion-conducting electrolyte (i.e. YSZ) to oxidize the anode fuel. The dissociated hydrogen and residual steam are exhausted from the SOFEC cathode and then separated by ...

2009-06-30

366

Obtainment of lanthanum oxide by fractionated precipitation method  

International Nuclear Information System (INIS)

... ammonium compounds benzilic acid chemical preparation lanthanum oxides

1979-01-01

369

Interaction of silicides in the Pd - Mo - Si ternary system  

International Nuclear Information System (INIS)

... chemical reactions high temperature lattice parameters microhardness

370

Inorganic chemistry of astatine  

International Nuclear Information System (INIS)

On the basis of experimental and extrapolated values the physico-chemical properties of astatine are reviewed considering all oxidation states.

380

Breath Test for Chemicals (Volatile Organic Compounds)  

Science.gov (United States)

Breath Tests; Human Volunteers; Pilot Study

2011-09-16

382

An R&D Exploratory Investigation of Resin Binders for the ...  

Science.gov (United States)

... Descriptors : *POLYMERS, *BINDERS, *HOWITZERS, *COMBUSTIBLE CARTRIDGE CASES, CHEMICAL COMPOSITION, PROPELLING ...

1980-10-01

384

Contamination and restoration of groundwater aquifers  

Energy Technology Data Exchange (ETDEWEB)

Humans are exposed to chemicals in contaminated groundwaters that are used as sources of drinking water. Chemicals contaminate groundwater resources as a result of waste disposal methods for toxic chemicals, overuse of agricultural chemicals, and leakage of chemicals into the subsurface from buried tanks used to hold fluid chemicals and fuels. In the process, both the solid portions of the subsurface and the groundwaters that flow through these porous structures have become contaminated. Restoring these aquifers and minimizing human exposure to the parent chemicals and their degradation products will require the identification of suitable biomarkers of human exposure; better understandings of how exposure can be related to disease outcome; better understandings of mechanisms of transport of pollutants in the heterogeneous structures of the ...

1993-04-01

385

Radioisotope production in the I.Ph.P.E. cyclotron for medical application  

International Nuclear Information System (INIS)

The production methods for seven radioisotopes, Ga-67, Sr-85, Pd-103, In-111, Tu-167, Hg-197 and Pb-203, by using a classical 1.5m cyclotron in the Institute of Physics and Power Engineering, Obninsk, USSR, are described. At present, more than 50 cyclotrons in different countries are used for the production of radioisotopes applied to medicine. Radioisotopes are produced with the cyclotron in the I.Ph.P.E. in the form of irradiated targets, which are delivered to Moscow radiopharmaceutical factory, where radiopharmaceuticals are produced on the base of these targets. The cyclotron is operated in two regimes providing the acceleration of protons, deuterons and alpha -particles. Two types of target assemblies are used for irradiation, the one is intended for the internal beam, and the other is for the external beam. The reactions used for the production of seven radioisotopes described above, the types of ...

386

Radioisotope production in the I. Ph. P. E. cyclotron for medical application  

Energy Technology Data Exchange (ETDEWEB)

The production methods for seven radioisotopes, Ga-67, Sr-85, Pd-103, In-111, Tm-167, Hg-197 and Pb-203, by using a classical 1.5m cyclotron in the Institute of Physics and Power Engineering, Obninsk, USSR, are described. At present, more than 50 cyclotrons in different countries are used for the production of radioisotopes applied to medicine. Radioisotopes are produced with the cyclotron in the I.Ph.P.E. in the form of irradiated targets, which are delivered to Moscow radiopharmaceutical factory, where radiopharmaceuticals are produced on the base of these targets. The cyclotron is operated in two regimes providing the acceleration of protons, deuterons and alpha -particles. Two types of target assemblies are used for irradiation, the one is intended for the internal beam, and the other is for the external beam. The reactions used for the production of seven radioisotopes described above, the types of ...

1982-01-01

387

Distortion-invariant color pattern recognition using multiple phase-shifted-reference-based joint transform correlation incorporating synthetic discriminant function  

Science.gov (United States)

This paper proposes a new pattern recognition system employing optical joint transform correlation (JTC) technique which offers a great number of advantages over similar digital techniques, including very fast operation, simple architecture and capability of updating the reference image in real time. The proposed JTC technique incorporates a synthetic discriminant function (SDF) of the target image estimated from different training images to make the pattern recognition performance invariant to noise and distortion. It then involves four different phase-shifted versions of the same target SDF reference image, which are individually joint transform correlated with the given input scene. When the correlation signals are combined, it produces a single cross-correlation peak corresponding to each potential target present in the given input scene. The proposed technique also includes a fringe-adjusted filter to generate a ...

2011-04-01

388

Investigation of the potential influence of production treatment chemicals on produced water toxicity  

International Nuclear Information System (INIS)

Production treatment chemicals represent a diverse collection of chemical classes, added at various points from the wellhead to the final flotation cell, to prevent operational upsets and enhance the separation of oil from water. Information in the literature indicates that while many treatment chemicals are thought to partition into oil and not into the produced water, there are cases where a sufficiently water soluble treatment chemical is added at high enough concentrations to suggest that the treatment chemical may add to the aquatic toxicity of the produced water. A study was conducted to evaluate the potential effect of production treatment chemicals on the toxicity of produced waters using the US EPA Seven-day Mysidopsis bahia Survival, Growth and Fecundity Test. Samples of produced water were collected and tested for toxicity from three platforms under ...

1993-11-14

389

Uses of laser optical pumping to produce polarized ion beams  

Energy Technology Data Exchange (ETDEWEB)

Laser optical pumping can be used to produce polarized alkali atom beams or polarized alkali vapor targets. Polarized alkali atom beams can be converted into polarized alkali ion beams, and polarized alkali vapor targets can be used to produce polarized H/sup -/ or /sup 3/He/sup -/ ion beams. In this paper the authors discuss how the polarized alkali atom beams and polarized alkali vapor targets are used to produce polarized ion beams with emphasis on the production of polarized negative ion beams.

1983-04-01

390

The HARP experiment first physics results  

CERN Document Server

The HARP experiment at CERN is performing extensive measurements of hadron production cross sections and secondary particle yields, in the momentum range 1.5-15 GeV/c, over the full solid angle and using a large set of cryogenic and solid targets. First measurements of hadron production cross-sections in the forward region are reported using an aluminium target 5% of an interaction length thick and a proton beam of 12.9 GeV/c. A preliminary analysis in the large angle region of elastic scattering events produced with the cryogenic hydrogen target at 3 GeV/c beam momentum is also presented.

2005-01-01

391

Separation of carrier-free "1"7"6","1"7"7W and "1"7"6","1"7"7Ta produced in "1"6O irradiated holmium target  

International Nuclear Information System (INIS)

Carrier-free radionuclides of tungsten and tantalum, "1"7"6","1"7"7W and "1"7"6","1"7"7Ta have been produced by heavy ion activation of holmium target with 97 MeV "1"6O"5"+ beam. Radiochemical separation scheme has been developed to isolate tungsten and tantalum radionuclides from the holmium target matrix. (author)

2001-11-01

392

Separation of carrier free "1"7"6","1"7"7W and "1"7"6","1"7"7Ta radionuclides produced in "1"6O activated holmium metal target  

International Nuclear Information System (INIS)

Carrier-free radioisotopes of tungsten, "1"7"6","1"7"7W, and their corresponding daughter radionuclides "1"7"6","1"7"7Ta, have been produced in holmium target by heavy ion activation with "1"6O"5"+ beam. An attempt has been made to separate these carrier-free radionuclides from bulk holmium target through LLX using cation exchanger HDEHP. (author)

2001-02-07

393

Recovery of radioactive thallium isotopes from lead and bismuth targets irradiated by 1-GeV protons  

Energy Technology Data Exchange (ETDEWEB)

A simple highly efficient procedure has been developed for recovery of thallium radioisotopes from lead and bismuth targets irradiated by 1-GeV protons. The procedure is based on the use of extraction chromatography. The cross-sections have been determined for formation of {sup 200}Pb, {sup 201}Pb, {sup 202m}Pb, and {sup 203}Pb radioisotopes in targets from lead with natural isotopic composition, irradiated by 1-GeV protons.

1995-03-01

394

Recovery of radioactive thallium isotopes from lead and bismuth targets irradiated by 1-GeV protons  

International Nuclear Information System (INIS)

A simple highly efficient procedure has been developed for recovery of thallium radioisotopes from lead and bismuth targets irradiated by 1-GeV protons. The procedure is based on the use of extraction chromatography. The cross-sections have been determined for formation of "2"0"0Pb, "2"0"1Pb, "2"0"2"mPb, and "2"0"3Pb radioisotopes in targets from lead with natural isotopic composition, irradiated by 1-GeV protons.

395

Preliminary Study of Plasma Stream Interaction with Tungsten Target within RPI-IBIS Facility  

International Nuclear Information System (INIS)

The paper presents results of experimental research on the interaction of a pulsed plasma-ion stream with a tungsten (W) target. The pulsed hydrogen plasma was produced within the RPI-IBIS (Multi-Rod Plasma Injector) facility at IPJ in Swierk. Measurements were carried out by means of optical spectroscopy and corpuscular diagnostic techniques. For experiments with the W-target the operational conditions (so-called PID mode) were chosen when a clean hydrogen plasma stream was generated. Attention was paid to the identification of WI and WII spectral lines.

2006-01-01

396

Modified-VSIMM algorithm with an application to the naval fire control technology  

British Library Electronic Table of Contents (United Kingdom)

A modified variable structure interacting multiple model (M-VSIMM) estimator for complex hybrid maneuver target tracking is presented. The M-VSIMM could potentially be applied to fire control systems (FCS) used on warships. Target model groups were designed using 3D dimensional dynamic target models. Optimal model group selection logic was proposed, contrary to the activation and termination logic in the original VSIMM. The system will respond faster with optimal model group selection logic. After performing simulations, the tracking performances of the Kalman, ?-?(-?), VDIE, IMM and M-VSIMM filters were compared under various maneuvering conditions.

2011-01-01

397

Experiments to investigate the effects of radiative cooling on plasma jet collimation  

CERN Document Server

Preliminary experiments have been performed to investigate the effects of radiative cooling on plasma jets. Thin (3 um - 5 um) conical shells were irradiated with an intense laser, driving jets with velocities > 100 km/s. Through use of different target materials - aluminium, copper and gold - the degree of radiative losses was altered, and their importance for jet collimation investigated. A number of temporally resoved optical diagnostics was used, providing information about the jet evolution. Gold jets were seen to be narrower than those from copper targets, while aluminium targets produced the least collimated flows.

2010-01-01

398

Convoy electron production in polycrystalline and monocrystalline targets  

Energy Technology Data Exchange (ETDEWEB)

The velocity distribution of electrons ejected close to the forward direction by 0.8-2 MeV/A ions traversing various solid targets, including a Au monocrystal, is measured in coincidence with emerging charge-selected ions. The velocity spectrum is observed to be independent of outgoing projectile velocity and charge state for polycrystalline targets. Measurements on the Au crystal under channeling conditions show dependences on final charge state, and are tentatively explained by assuming that the main contribution to the production yield comes from the non-channeled fraction of the ions. A simple model for the creation of the forward-ejected electrons is proposed, which accounts for most of the experimental findings.

1980-01-01

399

Computer-assisted rotation and multiple stationary irradiation technique  

International Nuclear Information System (INIS)

A computer-assisted rotation and stationary conformation radiotherapy system with overrunning multileaf collimators has been developed. This system can produce any shape of target volume, including a number of target areas outside the axis of the rotation, regardless of the location of the axis at 360"0 rotation irradiation. In addition, by changing the dose rate and deleting a partial region within a field, multiple stationary irradiation can produce more homogeneous target volumes - thus avoiding excessive irradiation to critical organs - than the rotation technique. (orig.).

400

Centroid and Envelope Dynamics of High-intensity Charged Particle Beams in an External Focusing Lattice and Oscillating Wobbler  

Energy Technology Data Exchange (ETDEWEB)

The centroid and envelope dynamics of a high-intensity charged particle beam are investigated as a beam smoothing technique to achieve uniform illumination over a suitably chosen region of the target for applications to ion-beam-driven high energy density physics and heavy ion fusion. The motion of the beam centroid projected onto the target follows a smooth pattern to achieve the desired illumination, for improved stability properties during the beam-target interaction. The centroid dynamics is controlled by an oscillating "wobbler", a set of electrically-biased plates driven by RF voltage. __________________________________________________

2010-04-28

401

The chemical link Brazil/Portugal. Abstracts of the 23. annual meeting of the Brazilian Chemical Society. v. 2; A ligacao quimica Brasil/Portugal. Resumos da 23. reuniao anual da Sociedade Brasileira de Quimica. v. 2  

Energy Technology Data Exchange (ETDEWEB)

Several works about annual meeting of the Brazilian Chemical Society are present.The search for medicinal chemistry, natural products, biological chemistry, and organic chemistry are shown. Conventional methods and some techniques are discussed and developments of new methods of determining are studied. The use of new chemical compounds, materials, structures and chemical analysis are shown.

2000-07-01

402

Technological press on the environment: comparison of the radiation and conventional processing  

International Nuclear Information System (INIS)

Transformation of row material to the consumption goods proceeds by the succession of various technologies using energy and chemicals. Relative contribution of both factors is broadly varied. The chemical reagents are not per se consumption goods and their production is auxiliary. Maximal usage of chemicals is observed in conventional technologies. On the contrary radiation technology does not need chemicals. Therefore usage of radiation technology leads to diminution of chemical processing and hence to the attenuation of the technological press on the environment. As examples the radiation technological methods in conversion of coal and biomass are considered. (author).

1994-09-11

403

Yields of Residual Nuclei from Proton-Irradiated Materials  

International Science & Technology Center (ISTC)

Experimental and Theoretical Study of the Residual Nuclide Production in 40-2600 MeV Proton-Irradiated Thin Targets of ADS Basic Materials

404

Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates?  

UK PubMed Central (United Kingdom)

Understanding the physical characteristics of the local microenvironment in which Mycobacterium tuberculosis resides is an important goal that may allow the targeting of metabolic processes...Full Text Available

2008-06-01

406

The influence of target backing on ion-beam electron spectra  

International Nuclear Information System (INIS)

Several different aspects of the influence of the target backing on in-beam electron spectra following compound nuclear reactions induced by accelerated ions at tandem energies irradiating backed targets are discussed in detail. This discussion is illustrated by a few typical examples, such as "1"2C"5"+ and "3"1P"1"0"+ beams at 4 MeV/u bombarding Sn(+Be), Sn(+Au), Pb(+C) backed targets. Moreover, the relative influence of electron backscattering, electron Doppler shift and Doppler broadening as well as #delta#-electron emission on the low energy electron spectra (E_e#<=#100 keV) obtained under such conditions are investigated in the frame of the available experimental data. (orig.).

407

The importance of an accurate target wave function in variational calculations for (e^{+}-H_{2}) scattering  

CERN Document Server

Using the complex Kohn method, we have calculated variational values of phase shifts and the annihilation parameter, Z_{eff}, for the elastic scattering of positrons by molecular hydrogen. Our results are sensitive to small changes in the accuracy of the wave function representing the target hydrogen molecule. We have developed a systematic approach to demonstrate that, at low positron energies, there are particular forms of the Kohn trial wave function for which the results of variational calculations are not reliable, even when the target wave function accounts for as much as 96.8% of the correlation energy of H_{2}. We find that reliable results can be recovered if our calculations are extended to admit more sophisticated target wave functions accounting for 99.7% of the correlation energy. Remaining discrepancies between theory and experiment are briefly discussed.

2008-01-01

408

The Growth Cone Cytoskeleton in Axon Outgrowth and Guidance  

UK PubMed Central (United Kingdom)

Axon outgrowth and guidance to the proper target requires the coordination of filamentous (F)-actin and microtubules (MTs), the dynamic cytoskeletal polymers that promote shape change and locomotion....Full Text Available

409

The Development of New Methods for Solving the Target ...  

Science.gov (United States)

... and 7 survey papers. On the inverse Stefan problem he wrote 3 research papers and 1 survey paper. The papers on inverse ...

1984-07-18

410

Target space duality I: general theory  

Energy Technology Data Exchange (ETDEWEB)

We develop a systematic framework for studying target space duality at the classical level. We show that target space duality between manifolds M and M-tilde arises because of the existence of a very special symplectic manifold. This manifold locally looks like MxM-tilde and admits a double fibration. We analyze the local geometric requirements necessary for target space duality and prove that both manifolds must admit flat orthogonal connections. We show how abelian duality, nonabelian duality and Poisson-Lie duality are all special cases of a more general framework. As an example we exhibit new (nonlinear) dualities in the case M=M-tilde=R{sup n}.

2000-09-25

411

Studies of relativistic heavy ion collisions at the AGS (Experiment 814)  

Energy Technology Data Exchange (ETDEWEB)

This report discusses the experimental setup of experiment 814 at Brookhaven AGS. This experiment involves the collision of silicon ions with target nuclei. The detector systems are discussed primarily. (LSP)

1990-01-01

412

Smoking and reproduction: The oviduct as a target of cigarette smoke  

UK PubMed Central (United Kingdom)

The oviduct is an exquisitely designed organ that functions in picking-up ovulated oocytes, transporting gametes in opposite directions to the site of fertilization, providing a suitable environment...Full Text Available

413

Simultaneous recognition and segmentation of cells: application in C.elegans  

UK PubMed Central (United Kingdom)

Motivation: Automatic recognition of cell identities is critical for quantitative measurement, targeting and manipulation of cells of model animals at single-cell resolution. It has been...Full Text Available

2011-10-15

414

Principles of antibody therapy.  

UK PubMed Central (United Kingdom)

The success of monoclonal antibodies in clinical practice is dependent on good design. Finding a suitable target is the most important part as other properties of the antibody can be altered by genetic...Full Text Available

1992-12-05

415

Novel Cytotoxic Vectors Based on Adeno-Associated Virus  

Wastenet

positive primary PymT breast cancer cells in primary co-cultured tumor tissue, suggesting target specificity of

416

Measured Temperatures of Solid Rocket Motors Dump Stored ...  

Science.gov (United States)

... TARGET SENSOR-MK 80 SERIES BOMBS ... 5-inch-, and 2.75-inch- diameter rocket motors that ... balance when compared to incoming solar radiation ...

1989-07-01

417

Knowledge-Based Identification of the ERK2/STAT3 Signal Pathway as a Therapeutic Target for Type 2 Diabetes and Drug Discovery  

British Library Electronic Table of Contents (United Kingdom)

Many existing agents for diabetes therapy are unable to restore or maintain normal glucose homeostasis or prevent the eventual emergence of hyperglycemia-related complication. Therefore, agents based on novel mechanisms are sought to complement and extend the current therapeutic approaches. Based on the initial paper research, we focused on active STAT3 as an attractive pharmacological target for type 2 diabetes. The subsequent text mining with a unique query to identify suppressors but not activators of STAT3 revealed the ERK2/STAT3 pathway as a novel diabetes target. The description of ERK2 inhibitors as diabetes target had not been found in our text mining research at present. The mechanism-based peptide inhibitor for ERK2 was identified using the knowledge of the KIM sequence, which ha...

2011-01-01

418

Johnson News - NASA  

Science.gov (United States)

Nov 21, 2003... for the European Space Agency's Automated Transport Vehicle, a new, uncrewed station cargo vehicle targeted for launch late next year. ...

419

Ion channels, transporters, and pumps as targets for heart failure  

UK PubMed Central (United Kingdom)

Congestive heart failure (CHF) is a leading cause of morbidity and mortality. CHF is marked by atrial and ventricular enlargement and reduced cardiac contractility, as well as an association...Full Text Available

2009-10-01

420

Imaging immune response in vivo  

UK PubMed Central (United Kingdom)

PurposeClinical trials have commenced to evaluate the feasibility of targeting malignant gliomas with genetically engineered cytolytic T-cells (CTLs) delivered directly...Full Text Available

2008-06-15

421

Heat shock proteins as emerging therapeutic targets  

UK PubMed Central (United Kingdom)

Chaperones (stress proteins) are essential proteins to help the formation and maintenance of the proper conformation of other proteins and to promote cell survival after a large variety of environmental...Full Text Available

2005-11-01

422

Genomics of human longevity  

UK PubMed Central (United Kingdom)

In animal models, single-gene mutations in genes involved in insulin/IGF and target of rapamycin signalling pathways extend lifespan to a considerable extent. The genetic, genomic and epigenetic influences...Full Text Available

2011-01-12

423

Gene therapy for ocular diseases  

UK PubMed Central (United Kingdom)

The eye is an easily accessible, highly compartmentalised and immune-privileged organ that offers unique advantages as a gene therapy target. Significant advancements have been made in understanding...Full Text Available

2011-05-01

424

GAVA: Spectral Simulation for In Vivo MRS Applications  

UK PubMed Central (United Kingdom)

An application that provides a flexible and easy to use interface to the GAMMA spectral simulation package is described that is targeted at investigations using in vivo MR spectroscopic methods....Full Text Available

2007-04-01

425

Evaluation of phenylpiperazines as targeting agents for neuroblastoma.  

UK PubMed Central (United Kingdom)

The potential of radiolabelled phenylpiperazines as agents for the detection and therapy of tumours of neural crest origin was evaluated by in vitro pharmacological studies with human neuroblastoma...Full Text Available

1996-09-01

426

Effects of voicing in the recognition of concurrent syllables (L)a)  

UK PubMed Central (United Kingdom)

This letter reports a study designed to measure the benefits of voicing in the recognition of concurrent syllables. The target and distracter syllables were either voiced or whispered, producing...Full Text Available

2009-12-01

427

Dynamic clamp with StdpC software  

UK PubMed Central (United Kingdom)

Dynamic clamp is a powerful method that allows the introduction of artificial electrical components into target cells to simulate ionic conductances and synaptic inputs. This method is based...Full Text Available

2011-03-01

428

Cooperative Charging Effects of Fibers From Electrospinning ...  

Science.gov (United States)

... In the Proceedings of INTC 2003, we studied charging effects on target coverage during electrospinning (16). ... of Fibers from Electrospinning of ...

2005-01-05

429

Cholinergic modulation of multivesicular release regulates striatal synaptic potency and integration  

UK PubMed Central (United Kingdom)

The pleiotropic actions of neuromodulators on pre- and postsynaptic targets present challenges to disentangling the mechanisms underlying regulation of synaptic transmission. Within the striatum,...Full Text Available

2009-09-01

430

Bacterial flora-typing with targeted, chip-based Pyrosequencing  

UK PubMed Central (United Kingdom)

BackgroundThe metagenomic analysis of microbial communities holds the potential to improve our understanding of the role of microbes in clinical conditions. Recent, dramatic improvements...Full Text Available

431

An Extended Kalman Filter for Use in a Shared Aperture ...  

Science.gov (United States)

... used to track a point source target ... A one sigma tracking error of .2 ... LOOKING INFRARED SYSTEMS, *KALMAN FILTERING, SIGNAL PROCESSING ...

1978-12-01

432

A comprehensive assessment of N-terminal signal peptides prediction methods  

UK PubMed Central (United Kingdom)

BackgroundAmino-terminal signal peptides (SPs) are short regions that guide the targeting of secretory proteins to the correct subcellular compartments in the cell. They are cleaved...Full Text Available

433

The application of computer modeling to health effect research  

Energy Technology Data Exchange (ETDEWEB)

In the United States, estimates show that more than 30,000 hazardous waste disposal sites exist, not including military installations, U.S. Department of Energy nuclear facilities, and hundreds and thousands of underground fuel storage tanks; these sites undoubtedly have their own respective hazardous waste chemical problems. When so many sites contain hazardous chemicals, how does one study the health effects of the chemicals at these sites? There could be many different answers, but none would be perfect. For an area as complex and difficult as the study of chemical mixtures associated with hazardous waste disposal sites, there are no perfect approaches and protocols. Human exposure to chemicals, be it environmental or occupational, is rarely, if ever, limited to a single chemical. Therefore, it is essential that we consider multiple ...

1996-12-31

434

Sources of toxicity and exposure information for identifying chemicals of high concern to children  

International Nuclear Information System (INIS)

Due to the large number of chemicals in commerce without adequate toxicity characterization data, coupled with an ineffective federal policy for chemical management in the United States, many states are grappling with the challenge to identify toxic chemicals that may pose a risk to human health and the environment. Specific populations (e.g., children, elderly) are particularly sensitive to these toxic chemicals. In 2008, the Children's Safe Product Act (CSPA) was passed in Washington State. The CSPA included specific requirements to identify High Priority Chemicals (HPCs) and Chemicals of High Concern to Children (CHCCs). To implement this legislation, a methodology was developed to identify HPCs from authoritative scientific and regulatory sources on the basis of toxicity criteria. Another set of chemicals of concern was then identified ...

2010-11-01

435

Supplier notification requirements under section 313 of the Emergency Planning and Community Right-to-Know Act (1991)  

International Nuclear Information System (INIS)

When Congress passed the Emergency Planning and Community Right-to-Know Act of 1986 (EPCRA), it created a number of new reporting requirements for companies that handle toxic chemicals and products containing toxic chemicals. Section 313 of EPCRA requires that certain manufacturers report annual releases to the environment of listed toxic chemicals and chemical categories. Because these manufacturers must know the toxic chemical composition of the products they use to be able to calculate releases accurately, EPA requires some suppliers of mixtures or trade name products containing one or more of the listed section 313 toxic chemicals to notify their customers. The pamphlet explains which suppliers must notify their customers, who must be notified, what form the notice must take, and when it must be sent.

436

Who's In The Dark: Satellite Based Estimates Of Electrification Rates  

Energy Technology Data Exchange (ETDEWEB)

A technique has been developed to estimate the percent population having electric power access based on the presence of satellite detected nighttime lighting. A global survey was conducted for the year 2006 using nighttime lights collected by the U.S. Air Force Defense Meteorological Satellite Program (DMSP) in combination with the U.S. Department of Energy Landscan population dataset. The survey includes results for 229 countries and more than 2000 subnational units. The results are compared to reported electrification rates for 87 countries compiled from a variety of sources by the International Energy Agency. The DMSP derived estimate of number of people worldwide who lack access to electricity is 1.62 billion, only slightly larger than the 1.58 billion estimated by the International Energy Agency.

2011-01-01

437

Waste reduction at the Savannah River Site  

Energy Technology Data Exchange (ETDEWEB)

The Savannah River Site (SRS) is a key installation for the production and research of nuclear materials for national defense and peace time applications and has been operating a full nuclear fuel cycle since the early 1950s. Wastes generated include high level radioactive, transuranic, low level radioactive, hazardous, mixed, sanitary, and aqueous wastes. Much progress has been made during the last several years to reduce these wastes including management systems, characterization, and technology programs. The reduction of wastes generated and the proper handling of the wastes have always been a part of the Site's operation. This paper summarizes the current status and future plans with respect to waste reduction to waste reduction and reviews some specific examples of successful activities.

1990-01-01

438

Waste reduction at the Savannah River Site  

Energy Technology Data Exchange (ETDEWEB)

The Savannah River Site (SRS) is a key installation for the production and research of nuclear materials for national defense and peace time applications and has been operating a full nuclear fuel cycle since the early 1950s. Wastes generated include high level radioactive, transuranic, low level radioactive, hazardous, mixed, sanitary, and aqueous wastes. Much progress has been made during the last several years to reduce these wastes including management systems, characterization, and technology programs. The reduction of wastes generated and the proper handling of the wastes have always been a part of the Site`s operation. This paper summarizes the current status and future plans with respect to waste reduction to waste reduction and reviews some specific examples of successful activities.

1990-12-31

439

Use of robotics for radioactive waste shipping and receiving  

International Nuclear Information System (INIS)

Radioactive waste shipping and receiving facilities presently planned for commercial and defense high-level nuclear waste will handle waste packages at frequencies far in excess of those in common practice today. If current limits for radiation levels at the cask surface and current handling methods are used, high cumulative personnel exposure to ionizing radiation is projected to occur. To reduce these exposure levels, alternate handling methods are being developed and demonstrated. The production nature of cask receiving operations, suggests commercial robotics be incorporated into a remote handling system to reduce predicted worker exposure to acceptable levels while maintaining or increasing throughput. The first phase of cask handling system development culminated in a proof-of-principle test demonstrating the feasibility of performing cask receiving and unloading operations in a remote and partially automated manner.

1986-06-16

440

Use of commercial robotics in radioactive waste shipping and receiving  

International Nuclear Information System (INIS)

Radioactive waste shipping and receiving facilities presently planned for commercial and defense nuclear waste will handle waste packages at frequencies far in excess of those in common practice today. Unacceptable personnel exposure to ionizing radiation is projected to occur if current limits for radiation levels at the cask surface and current handling methods are used. To reduce these exposure levels, alternate handling methods are being developed and demonstrated. The production nature of cask receiving operations suggests commercial robotics be incorporated into a remote handling system to reduce predicted worker exposure to acceptable levels, while maintaining or increasing throughput. The first phase of cask handling system development culminated in a proof-of-principle test demonstrating the feasibility of performing cask receiving and unloading operations in a remote and partially automated manner. 6 refs., 12 figs.

1985-04-21

441

Some issues on Japanese nuclear armament  

International Nuclear Information System (INIS)

The author considers the possibility that Japanese nuclear armament might be a realistic political option. Firstly introducing various issues on Japanese nuclear armament existing since long time ago, he classifies them according to the view point from internal and international problems. Internally, the armament is not possible at present on the ground of the nation's non-nuclear policy but it might be conditionally a choice in such case as the reliability of US nuclear deterrence declines or possibility of nuclear attack to Japan actually may be predicted. The armament may be possible technically and legally based on the consensus of the people. Various concerns by neighboring countries are discussed. Finally, the author stresses the importance of continuing to consolidate bilateral relationship with US, to deploy missile defensive system and to make every effort in the diplomatic activity for strong international ties and cooperation. (S. Ohno)

2007-07-01

442

Science and Technology Review March 2001  

Energy Technology Data Exchange (ETDEWEB)

This issue contains the following articles: (1) ''Safety and Security Are Enhanced by Understanding Plutonium''. (2) ''Inside the Superblock'' This area of Lawrence Livermore is home to one of just two US plutonium research and development facilities for defense. (3) ''Exploring the Fundamental Limits of Simulations'' Some of the nation's leading computer simulation experts gathered at Lawrence Livermore to discuss the common barriers facing their craft. (4) ''Plutonium Up Close...Way Close'' An examination of stockpile plutonium at the atomic level indicates so far, so good. (5) ''Shocked and Stressed, Metals Get Stronger'' Laser peening yields stronger, corrosion-resistant metals.

2001-03-01

443

Regulation and secretion of Xanthomonas virulence factors  

British Library Electronic Table of Contents (United Kingdom)

Abstract Plant pathogenic bacteria of the genus Xanthomonas cause a variety of diseases in economically important monocotyledonous and dicotyledonous crop plants worldwide. Successful infection and bacterial multiplication in the host tissue often depend on the virulence factors secreted including adhesins, polysaccharides, LPS and degradative enzymes. One of the key pathogenicity factors is the type III secretion system, which injects effector proteins into the host cell cytosol to manipulate plant cellular processes such as basal defense to the benefit of the pathogen. The coordinated expression of bacterial virulence factors is orchestrated by quorum-sensing pathways, multiple two-component systems and transcriptional regulators such as Clp, Zur, FhrR, HrpX and HpaR. Furthermore, virule...

2010-01-01

444

Reconnaissance radiological characterization for the White Point Nike Missile Site, San Pedro, California  

International Nuclear Information System (INIS)

This report is the result of field work performed at the former White Point Nike Missile Site, San Pedro, California. The Hazardous Waste Remedial Actions Program tasked the Oak Ridge National Laboratory Pollutant Assessments Group in Grand Junction, Colo., with this project. The objective was to determine whether or not radioisotopes possibly associated with past Department of Defense (DOD) operations were present and within accepted background levels. The radiation survey was accomplished by performing three independent radiation surveys, both outdoors and indoors, and random soil sampling. Initially, the site was land surveyed to develop a grid block system. A background radiation investigation was performed out in the San Pedro area.

445

Physics through the 1990s: Scientific interfaces and technological applications  

International Nuclear Information System (INIS)

Physics traditionally serves mankind through its fundamental discoveries, which enrich our understanding of nature and the cosmos. While the basic driving force for physics research is intellectual curiosity and the search for understanding, the nation's support for physics is also motivated by strategic national goals, by the pride of world scientific leadership, by societal impact through symbiosis with other natural sciences, and through the stimulus of advanced technology provided by applications of physics. This Physics Survey volume looks outward from physics to report its profound impact on society and the economy through interactions at the interfaces with other natural sciences and through applications of physics to technology, medicine, and national defense.

446

Ovis aries CR4 is involved in Mannheimia haemolytica leukotoxin-induced cytotoxicity  

British Library Electronic Table of Contents (United Kingdom)

Pneumonia caused by Mannheimia haemolytica is an important disease of domestic sheep (DS, Ovis aries) and cattle (BO). M. haemolytica is a normal commensal of the upper respiratory tract in ruminants, but during stress and viral infection it breaches the host innate mucosal defense and descents into lungs causing fibrinous pleuropneumonia. Leukotoxin (Lkt) produced by M. haemolytica is cytolytic to all subsets of ruminant leukocytes. Earlier, we and others have shown that DS and BO LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) can mediate Lkt-induced cytolysis. It is not clear whether CR4 (CD11c/CD18), which is involved in chemotaxis, phagocytosis and regulates host immune response can also mediate Lkt-induced cytolysis in ruminants. The host innate immune response to M. haemolytica is poorly ...

2010-01-01

447

Navy Occupational Health Information Management System (NOHIMS). Hazardous Materials Control Module. Users' manual  

Energy Technology Data Exchange (ETDEWEB)

The Hazardous Materials Control Module (HMC) is one module of four for the Industrial Health component. The HMC module was designed to inform employees of health and safety hazards in the workplace and to track the movement of hazardous materials through the facility. The module performs these functions by maintaining health and safety data on hazardous materials used in the facility, and by tracking who requests information about any hazardous materials. The HMC module gets its information from two sources. The first one is the Hazardous Materials Information System (HMIS), this is a national system that is used by the Department of Defense. It is loaded on to the system via tapes that contain all safety, health and transportation information about a particular product. The second is Material Safety Data Sheets (MSDS) that are procured by a particular site. This information is manually entered into their own personal system, which they give a site specific ...

1987-01-16

448

Longer exaggerated male genitalia confer defensive sperm-competitive benefits in an earwig  

British Library Electronic Table of Contents (United Kingdom)

As evidence mounts that male genitalia can affect relative fertilisation success, the role that sexual selection has played in the rapid and divergent evolution of genitalia is becoming increasingly recognized. Unfortunately, the limited functional understanding of these complex structures and their interactions with the female reproductive tract often limit interpretation regarding their evolution. Here, we address this issue using the earwig Euborellia brunneri, where both the male intromittent organ and the female spermatheca are highly exaggerated in length yet structurally simple. In a double mating design, we use the sterile male technique to study how sperm precedence patterns are affected by male genital length, male age, and the size of the male sperm storage organ, the seminal ve...

2011-01-01

449

Inhibitory effect of ?/?-carrageenan from red alga Tichocarpus crinitus on the development of a potato virus X infection in leaves of Datura stramonium L.  

British Library Electronic Table of Contents (United Kingdom)

The effect of ?/?-carrageenan from red alda Tichocarpus crinitus on the development of a potato virus X (PVX) infection in the leaves of Datura stramonium L. has been studied. The treatment of leaves with carrageenan stimulates a protein synthesis in the cells, causing an increase in the size of nucleoli and in the number of mitochondria and membranes of the rough endoplasmic reticulum. At the same time, such treatment slightly stimulates lytic processes, causing an increase in the number of smooth endoplasmic reticulum cisternae, dictyosomes, and cytoplasmic vacuoles and the formation of cytoplasmic electron-transparent zones. The carrageenan-induced stimulation of lytic processes results in the destruction of viral particles and can be considered as one of the defense mechanisms, prevent...

2010-01-01

450

Hanford Waste Vitrification Plant Quality Assurance Program description for high-level waste form development and qualification  

International Nuclear Information System (INIS)

The Hanford Waste Vitrification Plant Project has been established to convert the high-level radioactive waste associated with nuclear defense production at the Hanford Site into a waste form suitable for disposal in a deep geologic repository. The Hanford Waste Vitrification Plant will mix processed radioactive waste with borosilicate material, then heat the mixture to its melting point (vitrification) to forin a glass-like substance that traps the radionuclides in the glass matrix upon cooling. The Hanford Waste Vitrification Plant Quality Assurance Program has been established to support the mission of the Hanford Waste Vitrification Plant. This Quality Assurance Program Description has been written to document the Hanford Waste Vitrification Plant Quality Assurance Program.

1993-05-06

451

Hanford Waste Management Plan, 1987  

Energy Technology Data Exchange (ETDEWEB)

The purpose of the Hanford Waste Management Plan (HWMP) is to provide an integrated plan for the safe storage, interim management, and disposal of existing waste sites and current and future waste streams at the Hanford Site. The emphasis of this plan is, however, on the disposal of Hanford Site waste. The plans presented in the HWMP are consistent with the preferred alternative which is based on consideration of comments received from the public and agencies on the draft Hanford Defense Waste Environmental Impact Statement (HDW-EIS). Low-level waste was not included in the draft HDW-EIS whereas it is included in this plan. The preferred alternative includes disposal of double-shell tank waste, retrievably stored and newly generated TRU waste, one pre-1970 TRU solid waste site near the Columbia River and encapsulated cesium and strontium waste.

1987-01-01

452

Google Android: A State-of-the-Art Review of Security Mechanisms  

CERN Document Server

Google's Android is a comprehensive software framework for mobile communication devices (i.e., smartphones, PDAs). The Android framework includes an operating system, middleware and a set of key applications. The incorporation of integrated access services to the Internet on such mobile devices, however, increases their exposure to damages inflicted by various types of malware. This paper provides a comprehensive security assessment of the Android framework and the security mechanisms incorporated into it. A methodological qualitative risk analysis that we conducted identifies the high-risk threats to the framework and any potential danger to information or to the system resulting from vulnerabilities that have been uncovered and exploited. Our review of current academic and commercial solutions in the area of smartphone security yields a list of applied and recommended defense mechanisms for hardening mobile devices in general and the Android in particular. ...

2009-01-01

453

Genetic and environmental interactions determine plant defences against herbivores  

British Library Electronic Table of Contents (United Kingdom)

Summary 1. Plants express multiple defensive traits, but little is known about the genetic stability and phenotypic plasticity of these traits in nature. To investigate sources of variation and their potential ecological consequences for herbivores, we combined field observations of cyanogenic lima bean with laboratory experiments. 2. Field studies in South Mexico revealed a distinct variability of cyanogenic traits within and among wild lima bean populations. To differentiate among genetic variation and the impact of ambient conditions on plant phenotypes, we used seed grown plants as well as clones propagated from high (HC) and low cyanogenic (LC) wild type plants. 3. In growth chamber experiments, we cultivated plants under three intensities each of drought and salt stress, nutrient sup...

2011-01-01

454

Flight songs of Dusky Flycatchers: a response to bird-hunting raptors?  

British Library Electronic Table of Contents (United Kingdom)

ABSTRACT. Flight-song displays usually include distinctive vocalizations and behaviors that are probably energetically expensive and also likely to attract the attention of aerial predators. We observed flight songs performed by Dusky Flycatchers (Empidonax oberholseri) in two breeding populations. During 15 yr at Tioga Pass, California, we observed the display twice and, during 9 yr at Steamboat Mountain, British Columbia, we observed 21 flight-song displays. These displays were generally observed later in the breeding season, suggesting that they were not used for courtship, mate attraction, or territory defense. However, for 83% of these displays, a raptor was observed to be present, usually either an American Kestrel (Falco sparverius) or a Sharp-shinned Hawk (Accipiter striatus). We h...

2010-01-01

455

Electron accelerators, present and future applications  

International Nuclear Information System (INIS)

The development and occurrence of new electron accelerators and applications are according to the human society development law, as a whole. The period of economic standstill is generating an intense creative activity in the domain of science and engineering which also resulting in great achievements in the field of electron accelerators. This paper presents the basic principle of the electron beam applications and the accelerators required characteristics for their present and potential applications in the domains: radiation sources, diagnostics, radiation processing, energetics, environment, defense and basic sciences. All these are correlated to the new generation of accelerators which, for the acceleration process, may employ electromagnetic fields generated by standard sources, atomic lasers, free electron lasers, Cerenkov effect, Smith - Purcell effect, electron beams, plasma, excited atoms into a crystal or other sources. Some more important applications in ...

456

DNA repair: As influenced by age, nutrition, and exposure to toxic substances  

International Nuclear Information System (INIS)

In evaluating the risk associated with low levels of exposure to toxicants, it is clear that DNA repair, one of the main defenses against agent damage, is not a constant. It can be modified by age, time of day, and physiological state. Nutrition, especially caloric restriction (CR), can modify almost every step in the process of protecting genomic integrity. And history of exposure can modify DNA repair. Thus, the conditions of exposure are almost as important to toxicity as the exposure itself, even at the level of DNA repair. Extrapolation from high to low dose, to be consistent with what is known, should be less a mathematical exercise than an exercise in toxicological judgement, which puts the exposure in proper perspective. This appears to be true at almost every level in the process including a response with a toxic stimulus, even those thought to be very basic, such as DNA repair.

457

DARPA on your mind.  

Science.gov (United States)

Applied science may once again play a decisive role in changing the face of armed conflict, and the rest of human affairs, by shifting the battlefield to our very brains. The national-security establishment--and particularly the Pentagon's Defense Advanced Research Projects Agency (DARPA)--supports research at the intersection of neuroscience and national security that could ultimately enable authorities to do things like enhance (or muddle, or erase) memory, monitor crowds for individuals whose brain patterns correlate with aggressive behaviors, or control weapons from afar merely with thoughts. What are the dangers of such information falling into "the wrong hands," and are there any "right hands" for this kind of knowledge? Is any extension of human abilities justified by the need for government to protect its society? PMID:15986543

2004-01-01

458

Common aperture multispectral sensor flight test program  

Energy Technology Data Exchange (ETDEWEB)

This paper will provide an overview of the Common Aperture Multispectral Sensor (CAMS) Hardware Demonstrator. CAMS is a linescanning sensor that simultaneously collected digital imagery over the Far-IR (8 to 12 {mu}m) and visible spectral (0.55 to 1.1 PM) spectral bands, correlated at the pixel level. CAMS was initially sponsored by the U.S. Naval Air System Commands F/A-18 program office (PMA-265). The current CAMS field tests are under the direction of Northrop-Grumman for the Defense Nuclear Agency (DNA) in support of the Follow-On Open Skies Sensor Evaluation Program (FOSEP) and are scheduled to be conducted in April 1996. 8 figs., 4 tabs.

1996-11-01

459

Colour contrast in ballistic gelatine  

British Library Electronic Table of Contents (United Kingdom)

Gelatine is a reliable tissue simulant in wound ballistic experiments. The projectile penetrating the gelatine transfers energy and causes radial cracks according to the temporary cavity. Thus the crack length is a function of the energy spent in the medium. In practice the fissures are poorly contrasted for which reason an enhancement of contrast was searched. A series of six shoots with expanding bullets (9mmx19 Action-5, 9mmx19 Quick Defense 1, 5.56mmx45 Styx Action) was realized on 10% gelatine blocks at 4^oC temperature. Three blocks were marked with acryl paint on the front, three blocks were shot native. The blocks were cut in slices of 1cm thickness and optically scanned. The evaluation was performed according to Fackler's wound profile, the total crack length method and the polygo...

2010-01-01

460

British Nuclear Fuels PLC: report and accounts 1988-89  

International Nuclear Information System (INIS)

This item covers a meeting held between members of the United Kingdom government's energy committee and representatives of British Nuclear Fuels (BNFL) to discuss their Annual Report and Accounts for the year 1988-89. The committee explored the reasons for escalating predictions of the costs of nuclear power and why decommissioning costs are so difficult to estimate accurately so as to include them in cost per kilowatt hour of generated electricity. The relationship between BNFL and the Ministry of Defence (MoD) was explored, as was the MoD's relationship with the United States Department of Defense. BNFL's financial position should improve when the thermal oxide reprocessing plant at Sellafield becomes operational, and the Chapelcross and Calder Hall reactors may contribute income from electricity generation. (UK).

461

An old tool with potential new uses: return on investment  

British Library Electronic Table of Contents (United Kingdom)

Purpose - The purpose of this paper is to examine potential new uses of return on investment (ROI) in alternative methods for library assessment and valuation. Design/methodology/approach - Uses examples of recent uses of ROI by libraries to identify potential new applications of ROI in library assessment and valuation. Findings - ROI investment has historically been used by libraries for the assessment of past performance of library organizations in a reactive/defensive nature or for assessing the value of customer services. ROI has not been widely used as a proactive assessment tool, to introspectively assess administrative or other internal services, or as an offensive assessment and valuation tool, especially for intangible performance assessment and valuation. Originality/value - New ...

2007-01-01

462

Advanced conceptual design report: T Plant secondary containment and leak detection upgrades. Project W-259  

Energy Technology Data Exchange (ETDEWEB)

The T Plant facilities in the 200-West Area of the Hanford site were constructed in the early 1940s to produce nuclear materials in support of national defense activities. T Plant includes the 271-T facility, the 221-T facility, and several support facilities (eg, 2706-T), utilities, and tanks/piping systems. T Plant has been recommended as the primary interim decontamination facility for the Hanford site. Project W-259 will provide capital upgrades to the T Plant facilities to comply with Federal and State of Washington environmental regulations for secondary containment and leak detection. This document provides an advanced conceptual design concept that complies with functional requirements for the T Plant Secondary Containment and Leak Detection upgrades.

1995-05-12

463

Testing of CFC Targets by Plasma Heat Fluxes Relevant to Elms and Mitigated Disruptions in ITER  

International Nuclear Information System (INIS)

Carbon fibre composite (CFC) was irradiated by hot plasma streams at plasma gun facility MK-200UG. The CFC targets were tested by plasma loads relevant to Edge Localized Modes (ELM) and mitigated disruptions in ITER. Onset condition of CFC evaporation and properties of evaporated carbon were studied by use of infrared pyrometry and visible spectroscopy.

2006-01-01

464

Targeted suppression of Has2 mRNA in mouse cumulus cell-oocyte complexes by adenovirus-mediated short-hairpin RNA expression  

UK PubMed Central (United Kingdom)

RNA interference (RNAi) is an effective tool for studying gene function in oocytes, but no studies have targeted somatic cells of primary cultured cumulus cell-oocyte complexes (COCs). This...Full Text Available

2009-06-01

465

Targeted Capture and Next-Generation Sequencing Identifies C9orf75, Encoding Taperin, as the Mutated Gene in Nonsyndromic Deafness DFNB79  

UK PubMed Central (United Kingdom)

Targeted genome capture combined with next-generation sequencing was used to analyze 2.9 Mb of the DFNB79 interval on chromosome 9q34.3, which includes 108 candidate genes. Genomic...Full Text Available

2010-03-12

466

Structure functions at low Q^2: higher twists and target mass effects  

Energy Technology Data Exchange (ETDEWEB)

We review the physics of structure functions at low Q{sup 2}, focusing on the phenomenon of quark-hadron duality and the resonance-scaling transition, both phenomenologically and in the context of quark models. We also present a new implementation of target mass corrections to nucleon structure functions which, unlike existing treatments, has the correct kinematic threshold behavior at finite Q{sup 2} in the x -> 1 limit.

2006-05-22

467

Production of "2"0"3Pb by proton irradiation of Bi  

International Nuclear Information System (INIS)

Production of lead-203 by proton irradiation of bismuth metal has been investigated as a replacement method for commercially available lead-203. Targets of bismuth metal (0.1 cm thick) were irradiated for periods of 1-3 hours with 90 MeV protons. After processing of the target, the estimated yield of lead-2-3 was 30 millicuries/microamp.

1990-06-24

468

PV Conversion Technologies, Session: OPV, Sensitized, Seed (Presentation)  

Energy Technology Data Exchange (ETDEWEB)

The NREL Sensitized Solar Cell (SSC) Core Program supports the Solar America Initiative by: (1) targeting new devices and processes for commercialization by 2015 that are less expensive, more efficient, highly reliable, and environmentally benign; (2) collaborating with DOE OS/BES to conduct basic research targeting breakthroughs in key areas, such as ultra-high efficiency and/or ultra-low cost materials and devices.

2008-04-01

469

Modeled Neutron Induced Nuclear Reaction Cross Sections for Radiochemistry in the region of Iridium and Gold  

International Nuclear Information System (INIS)

We have developed a set of modeled nuclear reaction cross sections for use in radiochemical diagnostics. Systematics for the input parameters required by the Hauser-Feshbach statistical model were developed and used to calculate neutron induced nuclear reaction cross sections for targets ranging from osmium (Z = 76) to gold (Z = 79). Of particular interest are the cross sections on Ir and Au including reactions on isomeric targets.

2008-02-01

470

Kidney-specific allo- and autoantibodies in the alloantibody response to rat kidney: the use of kidney homogenate as a target for serological analysis.  

UK PubMed Central (United Kingdom)

LEW anti-DA kidney and DA anti-LEW kidney sera were assayed using an indirect 125I anti-immunoglobulin-binding assay with kidney homogenate as target. This allowed the full spectrum of antibodies to...Full Text Available

1980-04-01

471

In vitro atrazine-exposure inhibits human natural killer cell lytic granule release  

International Nuclear Information System (INIS)

The herbicide atrazine is a known immunotoxicant and an inhibitor of human natural killer (NK) cell lytic function. The precise changes in NK cell lytic function following atrazine exposure have not been fully elucidated. The current study identifies the point at which atrazine exerts its affect on the stepwise process of human NK cell-mediated lyses of the K562 target cell line. Using intracellular staining of human peripheral blood lymphocytes, it was determined that a 24-h in vitro exposure to atrazine did not decrease the level of NK cell lytic proteins granzyme A, granzyme B or perforin. Thus, it was hypothesized that atrazine exposure was inhibiting the ability of the NK cells to bind to the target cell and subsequently inhibit the release of lytic protein from the NK cell. To test this hypothesis, flow cytometry and fluorescent microscopy were employed to analyze NK cell-target cell co-cultures following atrazine ...

2007-06-01

472

Highly efficient gene silencing using perfect complementary artificial miRNA targeting AP1 or heteromeric artificial miRNA targeting AP1 and CAL genes  

UK PubMed Central (United Kingdom)

Gene silencing is a useful technique for elucidating biological function of genes by knocking down their expression. A recently developed artificial microRNAs (amiRNAs) exploits an endogenous...Full Text Available

2009-03-01

473

Electron accelerator unit for electron beam therapy  

Energy Technology Data Exchange (ETDEWEB)

An electron accelerator unit is described for electron beam therapy, comprising: a source of an electron beam; means for finally directing at least a portion of the beam to a therapy site, the directing means being mechanically independent of, and electrically isolated from, the source, and having a target area; and means for aligning the source with the directing means, the aligning means comprising means for projecting at least one beam of light from the source toward the target area.

1987-01-27

474

Electron accelerator unit for electron beam therapy  

International Nuclear Information System (INIS)

An electron accelerator unit is described for electron beam therapy, comprising: a source of an electron beam; means for finally directing at least a portion of the beam to a therapy site, the directing means being mechanically independent of, and electrically isolated from, the source, and having a target area; and means for aligning the source with the directing means, the aligning means comprising means for projecting at least one beam of light from the source toward the target area.

475

Double-electron-capture cross section for I/sup +/ in a magnesium-vapor target  

Energy Technology Data Exchange (ETDEWEB)

Measurements of the double-electron-capture process in which a positive ion of iodine becomes a negative ion in a single collision with a magnesium atom are reported between 20 and 90 keV. The cross section is comparable to that for the rare gases and not as large as might be expected from a two-valence-electron atom. This process is probably insignificant in the production of negative ion beams using a magnesium-vapor target.

1987-06-15

476

Development of High-Efficiency Low-Lift Vapor Compression System - Final Report  

Energy Technology Data Exchange (ETDEWEB)

PNNL, with cofunding from the Bonneville Power Administration (BPA) and Building Technologies Program, conducted a research and development activity targeted at addressing the energy efficiency goals targeted in the BPA roadmap. PNNL investigated an integrated heating, ventilation and air conditioning (HVAC) system option referred to as the low-lift cooling system that potentially offers an increase in HVAC energy performance relative to ASHRAE Standard 90.1-2004.

2010-03-31

477

Designing Human m1 Muscarinic Receptor-Targeted Hydrophobic Eigenmode Matched Peptides as Functional Modulators  

UK PubMed Central (United Kingdom)

A new proprietary de novo peptide design technique generated ten 15-residue peptides targeting and containing the leading nontransmembrane hydrophobic autocorrelation wavelengths, “modes”,...Full Text Available

2004-03-01

478

Achieving cholesterol targets by individualizing starting doses of statin according to baseline low-density lipoprotein cholesterol and coronary artery disease risk category: The CANadians Achieve Cholesterol Targets Fast with Atorvastatin Stratified Titration (CanACTFAST) study  

UK PubMed Central (United Kingdom)

BACKGROUND:Despite an increasing body of evidence on the benefit of lowering elevated levels of low-density lipoprotein cholesterol (LDL-C), there is still considerable concern that...Full Text Available

2010-02-01

479

A bioinformatics tool for linking gene expression profiling results with public databases of microRNA target predictions  

UK PubMed Central (United Kingdom)

MicroRNAs are short (∼22 nucleotides) noncoding RNAs that regulate the stability and translation of mRNA targets. A number of computational algorithms have been developed to help predict which...Full Text Available

2008-11-01

480

Radiation inactivation target size of rat adipocyte glucose transporters in the plasma membrane and intracellular pools  

Energy Technology Data Exchange (ETDEWEB)

The in situ assembly states of the glucose transport carrier protein in the plasma membrane and in the intracellular (microsomal) storage pool of rat adipocytes were assessed by studying radiation-induced inactivation of the D-glucose-sensitive cytochalasin B binding activities. High energy radiation inactivated the glucose-sensitive cytochalasin B binding of each of these membrane preparations by reducing the total number of the binding sites without affecting the dissociation constant. The reduction in total number of binding sites was analyzed as a function of radiation dose based on target theory, from which a radiation-sensitive mass (target size) was calculated. When the plasma membranes of insulin-treated adipocytes were used, a target size of approximately 58,000 daltons was obtained. For adipocyte microsomal membranes, we obtained target sizes of approximately 112,000 and 109,000 daltons prior ...

1987-06-15

481

Proton G{sub E}/G{sub M} from beam-target asymmetry  

Science.gov (United States)

The ratio of the proton's electric to magnetic form factor, G{sub E}/G{sub M}, can be extracted in elastic electron-proton scattering by measuring cross sections, beam-target asymmetry, or recoil polarization. Separate determinations of G{sub E}/G{sub M} by cross sections and recoil polarization observables disagree for Q{sup 2}>1 (GeV/c){sup 2}. Measurement by a third technique might uncover an unknown systematic error in either of the previous measurements. The beam-target asymmetry has been measured for elastic electron-proton scattering at Q{sup 2} = 1.51 (GeV/c){sup 2} for target spin orientation aligned perpendicular to the beam momentum direction. This is the largest Q{sup 2} at which G{sub E}/G{sub M} has been determined by a beam-target asymmetry experiment. The result, {mu}G{sub E}/G{sub M}=0.884{+-}0.027{+-}0.029, is compared to previous world data.

2006-09-15

482

One-class classifiers and their application to synthetic aperture radar target recognition  

Energy Technology Data Exchange (ETDEWEB)

Target recognition requires the ability to distinguish targets from non-targets, a capability called one-class generalization. To function as a one-class classifier, a neural network must have three types of generalization: within-class, between-class, and out-of-class. We discuss these three types of generalization and identify neural network architectures that meet these requirements. We have applied our one-class classifier ideas to the problem of automatic target recognition in synthetic aperture radar. We have compared three neural network algorithms: Carpenter and Grossberg`s algorithmic version of the Adaptive Resonance Theory (ART-2A), Kohonen`s Learning Vector Quantization (LVQ), and Reilly and Cooper`s Restricted Columb Energy network (RCE). The ART 2-A neural network has given the best results, with 100% within-class, and out-of-class generalization. Experiments show that the network`s ...

1992-10-01

483

One-class classifier networks for target recognition applications  

Energy Technology Data Exchange (ETDEWEB)

Target recognition requires the ability to distinguish targets from non-targets, a capability called one-class generalization. Many neural network pattern classifiers fail as one-class classifiers because they use open decision boundaries. To function as one-class classifier, a neural network must have three types of generalization: within-class, between-class, and out-of-class. We discuss these three types of generalization and identify neural network architectures that meet these requirements. We have applied our one-class classifier ideas to the problem of automatic target recognition in synthetic aperture radar. We have compared three neural network algorithms: Carpenter and Grossberg`s algorithmic version of the Adaptive Resonance Theory (ART-2A), Kohonen`s Learning Vector Quantization (LVQ), and Reilly and Cooper`s Restricted Coulomb Energy network (RCE). The ART 2-A neural network gives the best ...

1993-01-01

484

Integral cross sections of 50.5 MeV #alpha# particle inelastic scattering on 1p and (2s-1d) shell nuclei and scattering mechanisms  

International Nuclear Information System (INIS)

Obtained experimental data on integral cross sections (ICS) of inelastic scattering of 50.5 MeV #alpha# particles with the excitation of "6","7Li, "9Be, "1"2","1"3C, "1"4C, "1"4N, "2"0Ne, "2"4Mg, "2"8Si nucleus low-lying energy levels are discussed. Regularities, detected in the behaviour of ICS forward scattering for 20-90 deg angles and backscattering for 90-160 deg angles for the target-nucleus under investigation are considered. Effect of reaction open channel number on #alpha#-particle scattering ICS where n,p,d- and #alpha#-channels were considered as the main channels for all the target-nuclei, is discussed. Dependence of #alpha#-particle scattering ICS on the target-nucleus level excitation energy and dependences of reaction open channel number on the channel spin, calculated for 50.5 MeV #alpha# particles and different target nuclei are shown in the diagrams. It is noted that the observed ...

485

Donut-shaped high-dose configuration for proton beam radiation therapy  

Energy Technology Data Exchange (ETDEWEB)

Background: the authors report on the conception and first clinical application of a donut-shaped high-dose configuration for proton therapy (PT). This approach allows one to intensify target volume dose coverage for targets encompassing a critical, dose-limiting structure - like here, the cauda equina -, whilst delivering minimal dose to other healthy structures surrounding the target, thereby reducing the integral dose. Methods and results: intensity-modulated PT methods (IMPT) for spot scanning were applied to create and deliver a donut-shaped high-dose configuration with protons, allowing treating > 75% of the target with at least 95% of the prescribed dose of 72.8 CGE, whilst restricting dose to the cauda equina to 60-65 CGE. Integral dose was lower by a factor of 3.3 as compared to intensity-modulated radiotherapy with photons (IMXT). Conclusion: IMPT and spot scanning technology allow a ...

2005-01-01

486

Donut-shaped high-dose configuration for proton beam radiation therapy  

International Nuclear Information System (INIS)

Background: the authors report on the conception and first clinical application of a donut-shaped high-dose configuration for proton therapy (PT). This approach allows one to intensify target volume dose coverage for targets encompassing a critical, dose-limiting structure - like here, the cauda equina -, whilst delivering minimal dose to other healthy structures surrounding the target, thereby reducing the integral dose. Methods and results: intensity-modulated PT methods (IMPT) for spot scanning were applied to create and deliver a donut-shaped high-dose configuration with protons, allowing treating > 75% of the target with at least 95% of the prescribed dose of 72.8 CGE, whilst restricting dose to the cauda equina to 60-65 CGE. Integral dose was lower by a factor of 3.3 as compared to intensity-modulated radiotherapy with photons (IMXT). Conclusion: IMPT and spot scanning technology allow a ...

2005-01-01

487

Biocide and corrosion inhibition use in the oil and gas industry: Effectiveness and potential environmental impacts  

International Nuclear Information System (INIS)

Treatment chemicals are used in all facets of the natural gas industry (NGI) from well development through transmission and storage of natural gas. The multitude of chemicals used, combined with the dozens of chemical manufacturers and/or suppliers has lead to the availability of hundreds of possible chemical products. Because of the widespread use of chemical products and their numerous sources, the NGI needs access to consistent data regarding their effectiveness and potential environmental impacts. The objective of this work was to evaluate the effectiveness and potential environmental impacts of, chemical products used in the NGI. This assessment was initially focused on biocides and corrosion inhibitors and their use in the gas production, storage and transmission facilities, The overall approach was obtain the necessary data on ...

1995-03-27

488

Pore region of TRPV3 ion channel is specifically required for heat-activation  

UK PubMed Central (United Kingdom)

Ion-channels can be activated (gated) by a variety of stimuli including chemicals, voltage, mechanical force or temperature. Whereas molecular mechanisms of ion-channel gating by chemicals and...Full Text Available

2008-09-01

489

Hypothesis for induction and propagation of chemical sensitivity based on biopsy studies.  

UK PubMed Central (United Kingdom)

The reactive airways dysfunction syndrome (RADS), the reactive upper airways dysfunction syndrome (RUDS), the sick building syndrome (SBS), and the multiple chemical sensitivity syndrome (MCS) are overlapping...Full Text Available

1997-03-01

490

Force-dependent chemical kinetics of disulfide bond reduction observed with single-molecule techniques  

UK PubMed Central (United Kingdom)

The mechanism by which mechanical force regulates the kinetics of a chemical reaction is unknown. Here, we use single-molecule force–clamp spectroscopy and protein engineering to study the effect...Full Text Available

2006-05-09

491

Fluorine-19 NMR Chemical Shift Probes Molecular Binding to Lipid Membranes  

UK PubMed Central (United Kingdom)

The binding of amphiphilic molecules to lipid bilayers is followed by 19F NMR using chemical shift and line shape differences between the solution and membrane-tethered states of...Full Text Available

2008-05-22

492

Boundary conditions for the paleoenvironment: chemical and physical processes in the pre-solar nebula  

Energy Technology Data Exchange (ETDEWEB)

Two additional hyperfine components of the interstellar radical C3H were detected. In addition, methanol was discovered in interstellar clouds. The abundance of HCCN and various chemical isomers in molecular clouds was investigated.

1985-02-01

493

Application of tumor, bacterial and parasite susceptibility assays to study immune alterations induced by environmental chemicals  

UK PubMed Central (United Kingdom)

Model systems to study the effects of chemicals of environmental concern on bacterial and parasitic diseases as well as the immunosurveillance and destruction of transplantable tumor cells were described...Full Text Available

1982-02-01