Energy Technology Data Exchange (ETDEWEB)

Wheeling electric power, the transmission of electricity not owned by an electric utility over its transmission lines, is a term not generally recognized outside the electric utility industry. Investigation of the term`s origin is intriguing. For centuries, wheel has been used to describe an entire machine, not just individual wheels within a machine. Thus we have waterwheel, spinning wheel, potter`s wheel and, for an automobile, wheels. Wheel as a verb connotes transmission or modification of forces and motion in machinery. With the advent of an understanding of electricity, use of the word wheel was extended to be transmission of electric power as well as mechanical power. Today, use of the term wheeling electric power is restricted to utility transmission of power that it doesn`t own. Cogeneration ...

Science.gov (United States)

The patent application describes an anti-friction worm-wheel assembly wherein the anti-friction elements are rollers carried by the worm element. The rollers sequentially move through grooves in the edge surface of the wheel element to transmit drive forc...

J-STORE (Japan)

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Energy Technology Data Exchange (ETDEWEB)

This paper evaluates activities from 1981 to 1985 of the Donetskgormash association which develops and manufactures equipment for coal mining. The association has manufactured 1,410 hoists, 274 blowers and 26 bucket wheel excavators. Sixteen experimental units of new mining equipment have been developed, among others the RPM 3600-42.5/90 bucket wheel excavator (with a capacity of 3,600 m/sup 3//h for coal handling in storage yards of large power plants), the bucket wheel system used in the EhR 630-10.5/0.5 excavator and the PZ 1600-17/20 materials handling system. Among 20 equipment types manufactured from 1981 to 1985, 4 types were manufactured in the USSR for the first time (e.g. the MPP shaft sinking system and the VOD-50 mine blower). Use of new types of equipment manufactured by the association economized about 46 million rubles in coal mines. From 1986 to ...

Energy Technology Data Exchange (ETDEWEB)

There are many different types of open pit mining operations around the world, and the challenge for any drive system manufacturer is to produce a system(s) that will work satisfactorily in these mines. Several factors must be considered such as vehicle speed requirements, available engine horsepower, mine rolling resistance, grades, grade lengths, payload, and tire sizes. How well a particular drive system performs depends on the size, weight, and available tractive/retarding effort. In addition to performance, the system must also have an operating cost that will be acceptable over the life of the equipment. Today the choice of drive systems is not only between mechanical and electrical drives, but also within these categories are the different manufacturers. Regardless of how the power is provided to the rear wheels, the job must be accomplished reliably and ...

Energy Technology Data Exchange (ETDEWEB)

Repair and maintenance for equipment used in the Belchatow brown coal mine and organizational models of repair services in the mine are discussed. Maintenance of earthmoving equipment, spreaders, bucket wheel excavators, loaders and other coal handling equipment, belt conveyors and drive systems for belt conveyors is discussed. Repair shops in the mine also manufacture about 35% of spare parts and elements for equipment used in the mine. Reliability of mining equipment, repairs and repair capacity of the shops are discussed. Organizational models of repair services, equipment used by these services and repair personnel are described. Effects of repair services on operation of the mine are evaluated.

KoreaScience (Korea)

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International Nuclear Information System (INIS)

HLW disposal is one of the largest issue to utilize Nuclear power safely. In the past study, the concept, which buffer materials and Overpacked waste were transported into underground respectively, have shown. The concept of pre-assembled engineered barrier has advantage to simplify the logistics and emplacement procedure, however there are difficulties to support heavy weight of pre-assembled package by equipment under the condition of little clearance between tunnel and package. In this study, Combination of air bearing and two degree-of-freedom wheels were suggested for transportation, and air jack was suggested for unloading and emplacement system. Also, whole system for transportation and emplacement procedure was designed, and Scale model test was examined to evaluate the feasibility of these concept and functions. (author)

UK PubMed Central (United Kingdom)

The purpose of this study was to determine whether the use of wheeled mobility devices differed with respect to age, gender, residential setting, and health-related factors among older adults. A total...Full Text Available

CERN Document Server

The conceptual design of the support structures of the EM muon chambers is presented. On each side of the detector the EM chambers are arranged in four layers: one layer of MDTs and the three layers of TGCs. The chambers are mounted on four individual wheel structures per side. The four wheels are inclined by 1.23% and suspended from two longitudinal beams parallel to the beam axis. In order to allow for the opening of the ATLAS detector the wheels can be displaced longitudinally over a distance of 6 m. In addition individual wheels can be separated from each other by up to 1 m for maintenance purposes.

British Library Electronic Table of Contents (United Kingdom)

A small fleet of classic London Taxis (Black cabs) equipped with hydrogen fuel cell power systems is being prepared for demonstration during the 2012 London Olympics. This paper presents a Life Cycle Analysis for these vehicles in terms of energy consumption and CO2 emissions, focusing on the impacts of alternative vehicle technologies for the Taxi, combining the fuel life cycle (Tank-to-Wheel and Well-to-Tank) and vehicle materials Cradle-to-Grave. An internal combustion engine diesel taxi was used as the reference vehicle for the currently available technology. This is compared to battery and fuel cell vehicle configurations. Accordingly, the following energy pathways are compared: diesel, electricity and hydrogen (derived from natural gas steam reforming). Full Life Cycle Analysis, usin...

Science.gov (United States)

The ELXS concept is a novel, portable, micro-instrument targeted for the detection of mineralogic

International Nuclear Information System (INIS)

The National Ignition Facility (NIF) is a proposed Department of Energy facility which will contribute to the resolution of important Defense Program and inertial fusion energy issues for energy production in the future. The NIF will consist of a laser system with 192 independent beamlets transported to a target chamber. The target chamber is a multi-purpose structure that provides the interface between the target and the laser optics. The chamber must be capable of achieving moderate vacuum levels in reasonable times; it must remain dimensionally stable within micron tolerances, provide support for the optics, diagnostics, and target positioner; it must minimize the debris from the x-ray and laser light environments; and it must be capable of supporting external neutron shielding. The chamber must also be fabricated from a low neutron activation material. The fusion reaction in the ...

CERN Document Server

In the CERN approach to the design of a neutrino factory, the repetition frequency of the proton beam is high enough to consider stationary solid targets as a viable solution for multi-MW beams. The target consists of high density tantalum spheres of 2 mm diameter which can efficiently be cooled by passing a high mass flow He-gas stream through the voids between the Ta-granules. Very small thermal shocks and stresses will arise in this fine grained structure due to the relatively long burst of 3.3 ms from the SPL-proton linac. In a quadruple target system where each target receives only one quarter of the total beam power of 4 MW, conservative temperature levels and adequate lifetimes of the target are estimated in its very high radiation environment. A conceptual design of the integration of the target into the magnetic horn-pion-collector ...

International Nuclear Information System (INIS)

A system for real-time neutron radiography of moving objects is described. It comprise a source adapted to generate a continuous uninterrupted series of neutron pulses. Each pulse has a predetermined peak power and duration compatible with the framing times of a real-time video imaging system. A transporter moves an object to be examined to bring sequentially position selected portions of the object in the path of the pulses. Where the object itself has moving components, pulses are sequentially incident on the object. According to any dissimilarities, the object will alter the intensity of the neutrons passing therethrough. In order to record separately the changes in the neutron intensity, for each pulse, an imager is positioned to receive the neutron beam pulses which have been altered by their passage through the object and produce images indicating intensity alterations. A refrigerated beryllium filter can be used to effectively eliminate ...

Science.gov (United States)

... The Government of Egypt has requested a possible sale of 239 High Mobility Multi-purpose Wheeled Vehicles (HMMWV), electronic test set, spare ...

Energy Technology Data Exchange (ETDEWEB)

While there is growing interest in Real Time Pricing as a competitive tool, its adoption to date has been constrained by wariness on the part of many utilities and many of their customers. That wariness is not misplaced, for Real Time Pricing is not for everyone. In order for both utilities and their customers to benefit, the pricing system must be properly tailored for, and offered to, the appropriate audience. This paper discusses needs for identifying targets, implications of targeting of Real Time Pricing to various types of customers, and implications for design and marketing of such pricing systems. Examples from utility experiences are provided, and recommendations are offered for development of improved targeting of Real Time Pricing.

Energy Technology Data Exchange (ETDEWEB)

A 16 l liquid parahydrogen target has been developed for a measurement of the parity-violating {gamma}-asymmetry in the capture of polarized cold neutrons on protons in the {rvec n} + p {yields} d + {gamma} reaction by the NPDGamma collaboration. The target system was carefully designed to meet the stringent requirements on systematic effects for the experiment and also to satisfy hydrogen safety requirements. The target was designed to preserve the neutron polarization during neutron scattering on liquid hydrogen (LH{sub 2}), optimize the statistical sensitivity to the {rvec n} + p {yields} d + {gamma} reaction, minimize backgrounds coming from neutron interaction with the beam windows of the target cryostat, minimize LH{sub 2} density fluctuations which can introduce extra noise in the gamma asymmetry signal, and control systematic effects. The target ...

CERN Document Server

Here we show that self-propulsion in quantum vacuum may be achieved by rotating or aggregating magneto-electric nano-particles. The back-action follows from changes in momentum of electro-magnetic zero-point fluctuations, generated in magneto-electric materials. This effect may provide new tools for investigation of the quantum nature of our world. It might also serve in the future as a "quantum wheel" to correct satellite orientation in space.

Energy Technology Data Exchange (ETDEWEB)

This paper illustrates how the techniques developed by the authors for capital cost targeting of mass exchange networks can be applied to determination of capital investment targets for reduction in effluent for existing systems involving mass exchange. The results is an impact diagram which shows the relationship between effluent reduction and capital investment, indicating a region of limiting return on investment as well as the maximum possible reduction in effluent. (au)

Science.gov (United States)

...2010-10-01 2010-10-01 false Energy Policy Act target group certification...Acquisition Regulations System DEPARTMENT OF ENERGY CLAUSES AND FORMS SOLICITATION...Provisions and Clauses 952.226-73 Energy Policy Act target group...

Energy Technology Data Exchange (ETDEWEB)

Better properties of magnesium make it a natural choice for use as an anode material in rechargeable batteries. However, the magnesium alloy thin sheets used in rechargeable batteries were produced by ingot casting and rolling. That technology was so complex and the cost was high. Rapidly solidification by melt spinning is an effect way to solve that problem. In this paper, the technology of rapidly solidified (RS) ribbons in Mg-3%Al-1%Zn-0.2%Mn alloy has been investigated using melt spinning technique. The effect of wheel speed on thickness and microhardness of the ribbons is presented. Microhardness is found to increase with the wheel speed. Rapidly solidification leads to small grains (1{proportional_to}2 {mu}m). The plasticity of the ribbons was well. The quantity of Mg{sub 17}Al{sub 12} decreases with the increase in wheel speed. When the wheel speed reaches 1600 rpm, no Mg{sub 17}Al{sub 12} phase ...

Science.gov (United States)

... used to track a point source target ... A one sigma tracking error of .2 ... LOOKING INFRARED SYSTEMS, *KALMAN FILTERING, SIGNAL PROCESSING ...

UK PubMed Central (United Kingdom)

Immunotoxicity encompasses both reduced and heightened immune function. Diverse chemicals can impair functioning of the immune system. Both monographs and books have been devoted to detailed descriptions...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

A modified variable structure interacting multiple model (M-VSIMM) estimator for complex hybrid maneuver target tracking is presented. The M-VSIMM could potentially be applied to fire control systems (FCS) used on warships. Target model groups were designed using 3D dimensional dynamic target models. Optimal model group selection logic was proposed, contrary to the activation and termination logic in the original VSIMM. The system will respond faster with optimal model group selection logic. After performing simulations, the tracking performances of the Kalman, ?-?(-?), VDIE, IMM and M-VSIMM filters were compared under various maneuvering conditions.

Energy Technology Data Exchange (ETDEWEB)

Two refrains heard in the current retail wheeling debate are that a restructuring of the electric utility industry is inevitable and that its consequences are unpredictable. Notwithstanding the benefits of open competition, there are specific disadvantages of unlimited retail wheeling for some existing independent facilities and especially for hydropower plants. A capital-intensive industry, hydropower is not well-postured to compete effectively in the short-term, against new technologies and fuel sources available in the current marketplace. Hydropower is flat out non-competitive on a price basis with available new capacity. Unless hydro is afforded the same government supports offered to other renewable energy sources, only municipal plants with access to subsidized financing rates and pumped storage plants are going to be built.

Science.gov (United States)

Using static Michelson interferometer to get the spectrum information of measurement targets for spectrum identification, under the condition that the interference length is constant, the system can be optimized by BP neural network algorithm for the mixed spectral separation process. Thereby it can realize improving the recognition probability of camouflage target. Collecting the spectrum information in field of view (FOV) by the interferometer and linear array CCD detector, composing the set of mixed spectrum data, with known absorption spectrum of the material as a hidden layer of rules, it used BP neural network to separate the mixed spectrum data. Experiment with different distances, different combinations of mixed background spectrum as the initial data, using steel target (size: 1.5 m x 1.5 m) made of four kinds, the recognition probability of non-camouflage target is about ...

International Nuclear Information System (INIS)

The uranium target of a gas jet transport system for fission products has been modified by the addition of an aluminum cover foil. The new modification allows fission fragments of low mass to enter a continuous chemistry system while heavier fragments are stopped in the aluminum. The elimination of the heavier homologues allows development of simpler and faster chemical separation procedures. In addition, since the lighter fragments are slowed down by the cover foil a smaller target chamber can be used. This leads to a reduction in system holdup time. (orig.).

Energy Technology Data Exchange (ETDEWEB)

Describes performance of excavator teeth manufactured with a new hard alloy. The alloy was developed by the Donetskii Politeknicheskii Institute. Its composition consists of a high-chromium steel with a larger amount of titanium than serial alloy, and a nitrogen additive. Trial tests of new alloy teeth were carried out in the Severnyi and Vershinskii coal surface mines. The teeth were attached to EhRP, EhPG and EhR bucket wheel excavators. Abrasive wear of 129 experimental teeth and 134 serial teeth was compared for different excavation conditions. Test results are tabulated; advantages of the new experimental teeth are listed. 3 refs.

British Library Electronic Table of Contents (United Kingdom)

The main goal of local drug delivery is to increase the concentration of a specific therapeutic agent in a target tissue with minimal nontarget distribution. Compared to systemic therapy, local drug delivery provides a high level of therapeutic efficacy with minimal systemic effects. The current primary imaging modality for drug delivery has been x-ray angiography, but it has major limitations including anatomical ambiguity and inability to visualize the targeted tissues. Due to these inherent problems, MR guidance has been explored as an alternative imaging modality for guiding and monitoring of drug therapy. Recently, interventional MR (XMR) systems have been implemented that have both dual x-ray and MRI capabilities in a single suite and allow for real-time interventional procedures to ...

Science.gov (United States)

This paper proposes a new pattern recognition system employing optical joint transform correlation (JTC) technique which offers a great number of advantages over similar digital techniques, including very fast operation, simple architecture and capability of updating the reference image in real time. The proposed JTC technique incorporates a synthetic discriminant function (SDF) of the target image estimated from different training images to make the pattern recognition performance invariant to noise and distortion. It then involves four different phase-shifted versions of the same target SDF reference image, which are individually joint transform correlated with the given input scene. When the correlation signals are combined, it produces a single cross-correlation peak corresponding to each potential target present in the given input scene. The proposed technique also includes a fringe-adjusted filter ...

UK PubMed Central (United Kingdom)

The substantia nigra pars reticulata (SNR) represents an endogenous seizure suppressing system, which may be targeted to develop treatments for generalized or multifocal epilepsies. This review summarizes...Full Text Available

UK PubMed Central (United Kingdom)

Monogenic autoinflammatory diseases encompass a distinct and growing clinical entity of multisystem inflammatory diseases with known genetic defects in the innate immune system. The diseases...Full Text Available

UK PubMed Central (United Kingdom)

Treating brain tumors using inhibitors of angiogenesis is extensively researched and tested in clinical trials. Although anti-angiogenic treatment holds a great potential for treating primary and secondary...Full Text Available

UK PubMed Central (United Kingdom)

A detailed molecular characterization of nuclear mRNA export will require an in vitro system, allowing a biochemical reconstitution of transport. To this end, an mRNA export assay has...Full Text Available

International Nuclear Information System (INIS)

As part of the Nondestructive Evaluation Reliability Program sponsored by the US Nuclear Regulatory Commission, the Pacific Northwest Laboratory is developing a method that uses risk-based approaches to establish in-service inspection plans for nuclear power plant components. This method uses probabilistic risk assessment (PRA) results and Failure Modes and Effects Analysis (FEMA) techniques to identify and prioritize the most risk-important systems and components for inspection. The Surry Nuclear Power Station Unit 1 was selected for pilot applications of this method. The specific systems addressed in this report are the reactor pressure vessel, the reactor coolant, the low-pressure injection, and the auxiliary feedwater. The results provide a risk-based ranking of components within these systems and relate the target risk to target failure probability values for individual ...

British Library Electronic Table of Contents (United Kingdom)

Time delay neural networks trained with the backpropagation algorithm are derived for the gun fire control system to correct the miss distance between a target and the projectiles from the gun. Its performance is compared to optimum linear filter based on minimum mean square error [R.E. Kalman, A new approach to linear filtering and prediction problems, J. Basic Eng. 82D (1960) 35-44.]. The structure of the proposed neural controller is described and performance results are shown.

International Nuclear Information System (INIS)

The proliferation of 'botnets,' phishing schemes, denial-of-service attacks, root kits, and other cyber attack schemes designed to capture a system or network creates a climate of concern for system administrators, especially for those managing accelerator and large experimental-physics facilities, as they are very public targets. This paper will describe the steps being taken at the Advanced Photon Source (APS) to protect the infrastructure of the overall network with emphasis on security for the APS control system.

International Nuclear Information System (INIS)

At the Forschungszentrum Karlsruhe the HGF Strategy Fund project entitled 'Innovative Technology to Reduce Radiotoxicity' is performed which delivers an essential scientific contribution to the application oriented fundamental research for Accelerator Driven Systems (ADS). The addressed topics are in the areas of heavy liquid metal technology, thermalhydraulics and materials / corrosion. An ADS consists of three main components: an proton accelerator, a spallation target and a subcritical blanket. The strategic objective of an ADS is the transmutation of long-lived radioactive waste (plutonium, minor actinides and long-lived fission products) into short-lived isotopes or stable elements, thus closing the fuel cycle. The objective of one task of the HGF Strategy Fund Project is the numerical calculation of a closed spallation target module. In a consequent next step such a spallation target can be ...

International Nuclear Information System (INIS)

The "6"2Zn-"6"2Cu generator system is one of the few which yield a pure positron emitting daughter. The authors have developed a method for the preparation of this generator system following 32 MeV #alpha# particle bombardment of nickel targets. The chemical processing involves two stages: first a hydrous zirconium oxide column is used at pH 4-5 to separate the zinc and copper activities produced in the target nickel, and secondly, a conventional anion exchange column is used to retain the "6"2Zn and remove all copper activities in 2M HCl. This column serves as the "6"2Cu generator which will yield pure "6"2Cu repeatedly, free from "6"2Zn and other impurities, in a mixture of HCl and NaCl. A method is outlined also to obtain a solution of "6"2Zn using the hydrous zirconium oxide (HZO) column. "6"1Cu can be prepared as a by-product in the above procedure, but a method for the preparation of "6"1Cu alone ...

Energy Technology Data Exchange (ETDEWEB)

A novel compact CT-guided intensity modulated proton radiotherapy (IMPT) system is described. The system is being designed to deliver fast IMPT so that larger target volumes and motion management can be accomplished. The system will be ideal for large and complex target volumes in young patients. The basis of the design is the dielectric wall accelerator (DWA) system being developed at the Lawrence Livermore National Laboratory (LLNL). The DWA uses fast switched high voltage transmission lines to generate pulsed electric fields on the inside of a high gradient insulating (HGI) acceleration tube. High electric field gradients are achieved by the use of alternating insulators and conductors and short pulse times. The system will produce individual pulses that can be varied in intensity, energy and spot width. The IMPT planning ...

CERN Document Server

A calorimetric-time-of-flight (CTOF) technique was used for real-time, high-precision measurement of neutron spectrum at the angle of 175 degrees from the initial proton beam direction, which hits a face plane of a cylindrical iron target of 20 cm in diameter and 25 cm thick. A comparison was performed between the neutron spectra predicted by the MARS and the MCNPX code systems and measured by experiments for 0.4-, 0.6-, 0.8-, 1.0-, and 1.2-GeV protons.

Energy Technology Data Exchange (ETDEWEB)

The chemical separation of carrier-free /sup 203/Pb following deuterium bombardment of a /sup 203/Tl target is described. Coprecipitation from strontium sulphate was used to separate the /sup 203/Pb from a solution of the thallium target in sulphuric acid. The SrSO/sub 4/ precipitate was filtered, washed and dissolved in hydrochloric acid, from which /sup 203/Pb was again separated by precipitation on sodium chloride from a strongly acid solution. Advantages of the system are discussed and optimum conditions given.

Energy Technology Data Exchange (ETDEWEB)

When the use of retarders in utility vehicles increased in the middle of the 80s, the Forschungsvereinigung Automobiltechnik (FAT) commissioned a study on the safety aspect of this braking technology in trucks. Retarders are wear-free permanent brakes that are fitted in the drive transmission system of utility vehicles, thereby generating braking forces only at the wheels of the live shaft. The question of the possible overbraking of the live shafts was just as well investigated as the interaction between the retarder and service brake in so-called integrated braking systems, and both under conditions of low adhesion as well as in the border area of the dynamics of vehicle movement. This subject met with considerable joint interest on the part of the motor vehicle industry as well as of manufacturers of towed vehicles and unit sets. FAT, therefore, commissioned the Institut fuer Kraftfahrwesen of the University of Hannover ...

International Nuclear Information System (INIS)

One of several methods to build YSZ electrolyte of SOFC is plasma spraying. This system heats particle to a melting point and then pushing them into target and forming a deposition. This paper presents heating studies of YSZ particle in plasma jet. By simple model it is shown that the required time such those YSZ particle with grain size of 50 ?m to be melt is around 12 x 10-4 second. (author)

CERN Document Server

Constraints on target chamber first wall and target designs that will enable NIF debris shields to survive

Science.gov (United States)

Measurements using radioactive targets are important for the determination of key reaction path ways associated with the synthesis of the elements in nuclear astrophysics (sprocess), advanced fuel cycle initiative (transmutation of radioactive waste), and stockpile stewardship. High precision capture cross-section measurements are needed to interpret observations, predict elemental or isotopical ratios, and unobserved abundances. There are two new detector systems that are presently being commissioned at Los Alamos National Laboratory for very precise measurements of (n,{gamma}) and (n,f) cross-sections using small quantities of radioactive samples. DANCE (Detector for Advanced Neutron-Capture Experiments), a 4 {pi} gamma array made up of 160 BaF{sub 2} detectors, is designed to measure neutron capture cross-sections of unstable nuclei in the low-energy range (thermal to {approx}500 keV). The high granularity and high detection efficiency of ...

Science.gov (United States)

An analysis of the diagnosis of loading and service dependability of a rail-mounted excavator used in surface lignite mining is described. Wheel power vibrations in electric motor bearings and electric motor input bearings to the gearbox were measured in situ, in horizontal, vertical, and axial directions. The data were analyzed using a mathematical relationship. The results are presented in a loading diagram that shows the deterioration and the acceptable lower bound of machine conditions over time. Work is continuing. 5 refs., 1 fig.

Science.gov (United States)

EOS Technologies has been commissioned to design and build a unique 2.4m astronomical telescope for the Magdalena Ridge Observatory. This telescope utilizes a high quality primary mirror and cell from a now decommissioned military application. This paper describes the project and gives an overview of the telescope design. The Magdalena Ridge Observatory (MRO) 2.4 meter telescope will be primarily utilized to observe, track, and characterize solar system astronomical targets, Earth satellites, space vehicles, and terrestrial military targets. The telescope's rapid tracking (slew rates are 10o/sec) will allow it to move to any target and acquire data within one minute of receipt of notice. In this way, the telescope will be used to capitalize on targets of opportunity that occur in asteroid studies (e.g., Near Earth Objects) and in astrophysics, such as gamma ray bursts and other ...

International Nuclear Information System (INIS)

The paper proposes a concept of power driver for industrial thermonuclear reactor based on inertial thermonuclear synthesis (ITS). The circuit is based on the application of free electron laser (FEL) as a energy source for thermonuclear target compression which becomes feasible due to the application of a radically new circuit of FEL-amplifier. In the project under consideration the FEL-based laser system operates on the wave length of 0.5 micrometer. The full energy of laser radiation equals 1 MJ. This energy is delivered to the target in the pulse whose length is controlled within the range of 0.1-2 ns. The laser system brightness is 4 x 10"2"2 W cm"-"2. The FEL operating pulse repetition frequency is 40 Hz, full efficiency of electricity conversion into the energy of optical radiation is 11%. 9 refs., 3 figs., 2 tabs.

International Nuclear Information System (INIS)

A method for the determination of stereotaxic coordinates in radiography, e.g. angiography, pneumoencephalography or digital vascular radiography, is described. A special localization frame containing radiopaque structures and scales defines a diagnostic coordinate system. This frame is fixed to the X-ray-table prior to the radiographic procedure and two projections are obtained at arbitrary angles to each other. The focus-film distances do not have to be fixed. The target coordinates are then determined either by a simple graphical procedure or with the use of a digitizing x-y-table, by a computer. With the computer method the films are placed on the digitizing table and the target and a few reference points are marked using a cursor. From the relative positions the computer calculates the coordinates. With the special head fixation system, coordinates of structures visualized in radiographic ...

DEFF Research Database (Denmark)

This paper describes the LYCOS system, an experimental co-synthes is environment. We present the motivation and philosophy of LYCOS and after an overview of the entire system, the individual parts are described. We use a single CPU, single ASIC target architecture and we describe the techniques we use to estimate metrics concerning hardware, software and communication in this architecture. Finally we present a novel partitioning technique called PACE, which has shown to produce excellent results, and we demonstrate how partitioning is used to do design space exploration.

Energy Technology Data Exchange (ETDEWEB)

By contrast to the large mass, complexity and recirculating power of conventional drivers for inertial confinement fusion (ICF), antiproton annihilation offers a specific energy of 90MJ/{micro}g and thus a unique form of energy packaging and delivery. In principle, antiproton drivers could provide a profound reduction in system mass for advanced space propulsion by ICF. We examine the physics underlying the use of antiprotons ({bar p}) to drive various classes of high-yield ICF targets by the methods of volumetric ignition, hotspot ignition and fast ignition. The useable fraction of annihilation deposition energy is determined for both {bar p}-driven ablative compression and {bar p}-driven fast ignition, in association with 0-D and 1-D target burn models. Thereby, we deduce scaling laws for the number of injected antiprotons required per capsule, together with timing and focal spot requirements. The kinetic energy of the ...

Energy Technology Data Exchange (ETDEWEB)

NIF target diagnostics are being developed to observe and measure the extreme physics of targets irradiated by the 192-beam laser. The response time of target materials can be on the order of 100ps--the time it takes light to travel 3 cm--temperatures more than 100 times hotter than the surface of the sun, and pressures that exceed 109 atmospheres. Optical and x-ray diagnostics were developed and fielded to observe and record the results of the first 4-beam experiments at NIF. Hard and soft x-ray spectra were measured, and time-integrated and gated x-ray images of hydrodynamics experiments were recorded. Optical diagnostics recorded backscatter from the target, and VISAR laser velocimetry measurements were taken of laser-shocked target surfaces. Additional diagnostics are being developed and commissioned to observe and diagnose ignition implosions, including various neutron and ...

Wastenet

... Targeted fields of research Continuation of ongoing research - Finalising detailed design work on the ITER project; getting JET operational at full power; Improvement of the basic concepts of fusion devices - Fusion plasmas; theoretical studies; technology watch on research into inertial confinement; new experimental concepts and systems; etc.; Long-term technology - Preparations for building a demonstration reactor (development of tritium breeding blankets; prospective ...

International Nuclear Information System (INIS)

A large IMF- and event characterizing multidetector system (CHICSI) is under development for storage ring experiments. In ''test'' experiments with telescopes of CHICSI type the IMF production has been measured for "1"4N induced reactions at 14A and 32A MeV. Detailed information about the emission sources, particularly from the IMF yield in reactions with isotope separated targets and from isobaric yield ratios in the sub-Coulomb region is discussed. (orig.).

International Nuclear Information System (INIS)

A computer-based beam dosimetry measurement system for boron neutron capture therapy provides accurate, sensitive, and rapid readout and recording of all beam dose components, epithermal and thermal neutron flux, and gamma-ray dose rate. This dosimetric system includes input from the characterization of the epithermal neutron beam developed at the Massachusetts Institute of Technology, actual BPA pharmacokinetic data from a specific human subject being irradiated, output of MacNCTPLAN, a treatment planning system developed by the authors group, and input from the five on-line beam detectors. The purpose of this system and associated readout systems is to ensure that the desired dose is delivered to the subject within acceptable dose tolerances, e.g., #+-#5% of the target dose, and that any perturbations in the neutron beam that may occur during irradiation can ...

Energy Technology Data Exchange (ETDEWEB)

The UK government's economy-wide 60% carbon dioxide reduction target by 2050 requires a paradigm shift in the whole energy system. Numerous analytical studies have concluded that the power sector is a critical contributor to a low carbon energy system, and electricity generation has dominated the policy discussion on UK decarbonisation scenarios. However, range of technical, social and market challenges, combined with alternate market investment strategies mean that large scale deployment of key classes of low carbon electricity technologies is fraught with uncertainty. The UK MARKAL energy systems model has been used to investigate these long-term uncertainties in key electricity generation options. A range of power sector specific parametric sensitivities have been performed under a 'what-if' framework to provide a systematic exploration of least-cost energy ...

Energy Technology Data Exchange (ETDEWEB)

The ALICE heavy-ion particle physics experiment is currently being built at CERN near Geneva. It will use a PC cluster of 900 dual-processor machines for the last stages of the data readout process and a network of 400 microcomputers for the configuration and control of the cluster nodes. One of the most important objectives to be achieved in such experiments is to guarantee the utilized devices are running correctly during the experiment life-time. A second aspect is the extremely high availability and reliability requirements of the applications being run, the so called high level trigger (HLT). The SysMES framework is a scalable, decentralized, fault tolerant, dynamic, rule based tool set for the monitoring of networks of target systems and applications. The management algorithms consist of the following steps: system and application monitoring, recognition of undesirable states, event (message) generation, local event ...

British Library Electronic Table of Contents (United Kingdom)

This study emphasizes the need for a systematic and in-depth connection between the progress in quantum theory of energetic ion collisions and applications to hadron therapy. Scattering theory for fast ion beams has reached its stage of development where accurate and robustly applicable methodologies can advantageously be exported to applied fields such as space research, fusion energy program, medicine, etc. In particular, distorted wave collision theories at high energies readily provide total, partial and fully differential cross sections for inelastic collisions of ionic projectiles with any target system. By numerous and thorough testings, such theoretical cross sections were found to exhibit excellent agreement with experimental data on atomic targets. Adequate extensions of these me...

Energy Technology Data Exchange (ETDEWEB)

A nanosuspension of magnetically tagged metronidazole was developed by the solvent displacement method coupled with ultrasonication and was evaluated for its physicochemical properties. The drug release from metronidazole magnetic nanosuspension at pH 1.2 and 7.0 shows maximum correlation coefficient for zero order and Higuchi model, respectively. The anthelmintic activity of the formulated metronidazole magnetic nanosuspension was evaluated on Indian earthworms (Pheretima poi). Metronidazole magnetic nanosuspension at a dose of 10 and 50 mg/ml shortened by 31% and 34%, respectively, the mean time to death of the earthworms when compared against a non-magnetic metronidazole suspension. Thus, the developed metronidazole magnetic nanosuspension showed potent, controlled and targeted drug action and might be a good therapeutic avenue in combating infectious GI disorders.

Energy Technology Data Exchange (ETDEWEB)

A calorimetric sensor with several novel design features has been developed. These sensors will provide an accurate sampling of thermal power density and energy deposition from proton beams incident on target components of accelerator-based systems, such as the Accelerator Production of Tritium Project (APT) and the Spallation Neutron Source (SNS). A small, solid slug (volume = 0.347 cc) of target material is suspended by kevlar fibers and surrounded by an adiabatic enclosure in an insulating vacuum canister of stainless steel construction. The slug is in thermal contact with a low-mass, calibrated, 100-k{Omega} thermistor. Power deposition caused by the passage of radiation through the slug is calculated from the rate of temperature rise of the slug. The authors have chosen slugs composed of Pb, Al, and LiAl.

Science.gov (United States)

A novel drug delivery system for the treatment of brain tumors was formulated by methotrexate (MTX)-loaded polymeric nanoparticles (NPs) based on Glycol chitosan (GCS) and Dextran sulfate (DS). The physicochemical properties of resulting particles were investigated, evidencing the contribution of these nanoparticles for brain targeting. In vitro release of MTX was also evaluated. The GCS-DS nanoparticles have been developed based on the modulation of ratio show promise as a system for controlled delivery of the drug to the brain. PMID:21782844

Wastenet

... We strive to meet the needs of our members at as low a cost as possible. Visit website eSight Energy eSight Energy ...eSight® is the most advanced fully web enabled energy monitoring and targeting package on the market. This comprehensive and intuitive energy management suite ...Drinks Company We have developed the worlds most environmentally friendly cold drinks vending system. Over 40 different drinks available which are good for ...EcoSort® recycling system has been designed to offer customers a unique and flexible solution for the source separation of waste materials. Visit website ...

International Nuclear Information System (INIS)

Electron and ion beam dynamics of the PF-1000 facility were investigated for the first time at its upper energy limit (?1 MJ) in relation to neutron emission, the pinch's plasma ('target') characteristics and some other parameters with the help of a number of diagnostics with ns temporal resolution. Special attention was paid to the temporal and the spatial cross correlations of different phenomena. Results of these experiments are in favour of a neutron emission model based on ion beam-plasma interaction with three important features: (1) the plasma target is hot and confined during a few 'inertial confinement times'; (2) the ions of the main part of the beam are magnetized and entrapped around the pinch plasma target for a period longer than the characteristic time of the plasma inductive storage system and (3) ion-ion collisions (both fusion collisions, due to head-on impacts and Coulomb collisions) ...

Science.gov (United States)

Magnetic drug targeting, using core-shell magnetic carrier particles loaded with anti-cancer drugs, is an emerging and significant method of cancer treatment. Gold shell-iron core nanoparticles (Fe@Au) were synthesized by the reverse micelle method with aqueous reactants, surfactant, co-surfactant and oil phase. XRD, XPS, TEM and magnetic property measurements were utilized to characterize these core-shell nanoparticles. Magnetic measurements showed that the particles were superparamagnetic at room temperature and that the saturation magnetization decreased with increasing gold concentration. The anti-cancer drug doxorubicin (DOX) was loaded onto these Fe@Au nanoparticle carriers and the drug release profiles showed that upto 25% of adsorbed drug was released in 80 h. It was found that the amine (-NH2) group of DOX binds to the gold shell. An in vitro apparatus simulating the human circulatory system was used to determine the retention of these ...

Energy Technology Data Exchange (ETDEWEB)

X-ray ablation of material from the first wall and other components of an ICF (Inertial Confinement Fusion) chamber is a major threat to the laser final optics. Material condensing on these optics after a shot may cause damage with subsequent laser shots. To ensure the successful operation of the ICF facility, removal rates must be predicted accurately. The goal for this dissertation is to develop an experimentally validated x-ray response model, with particular application to the National Ignition Facility (NIF). Accurate knowledge of the x-ray and debris emissions from ICF targets is a critical first step in the process of predicting the performance of the target chamber system. A number of 1-D numerical simulations of NIF targets have been run to characterize target output in terms of energy, angular distribution, spectrum, and pulse shape. Scaling of output characteristics with ...

International Nuclear Information System (INIS)

Our institute has been investigating laser-produced tin, lithium and xenon plasma for extreme ultraviolet (EUV) light source of EUV lithography system, and found the highest conversion efficiency of 3% at 13.5 nm in 2% bandwidth. In the present paper, we introduce fabrication methods of density-controlled tin targets to generate relatively monochromatic EUV, and higher conversion efficiency than bulk tin. The first method is the nano-template method, where liquid tin solution was immersed into a polymer film with monodispersed size nano-particle. The density can be controlled by tin concentration of the solution. The target can be classified into mass-limited target. We have shown a tendency of monochromatic EUV emission around 13.5 nm with decreasing of tin density. The intensity was higher than tin foil with bulk density. The tendency has a merit to mitigate heat effect of the first EUV mirror. The ...

Energy Technology Data Exchange (ETDEWEB)

R and D of the robot control system was conducted in the following items: 1) integrated open control system, 2) remote control robot manipulation language, 3) human factor robot use built-in LAN system, 4) built-in actuator driver. In 1), there were some problems to be pointed out around the system, but the effectiveness was confirmed as system architecture of each verification item. In 2), development/design were made of RCML(R-Cube Manipulation Language) as a remote robot manipulation language, telecommunication protocol, and the experimental system, and the international standardization was targeted. In 3), the R and D was conducted of the realtime telecommunication protocol which clears the standards for the distributed control required for construction of human factor robot and the advanced realtime micro-controller, ULSI, which is the ...

Energy Technology Data Exchange (ETDEWEB)

Autonomous robots or remotely operated vehicles have raised high hopes in the military and industrial communities because of the potential safety improvement and gain of productivity they may provide. Waste management on nuclear sites, pallet manipulation in factories, interventions on battle-fields, etc., are actively studied. A lot of these applications require powerful four-wheel vehicles, the kinematics of which is similar to that of a car. Such vehicles have three degrees of freedom: the (x,y) positions in a plane and the orientation of the vehicle. Path planning is often understood as only changing the position of the vehicle, whereas the tasks performed by this kind of robot requires a perfect orientation of the vehicle: forklifting a pallet or docking at a loading or unloading station requires accuracy in the orientation of the vehicle. It is this requirement and the kinematic constraints of the motion mode which have led to the path-planning algorithm ...

Energy Technology Data Exchange (ETDEWEB)

The United States and Russia have agreed to jointly develop a solar dynamic (SD) system for flight demonstration on the Russian Mir space station starting in late 1997. Two important components of this SD system are the solar concentrator and heat receiver provided by Russia and the US, respectively. This paper describes optical analysis of the concentrator and solar flux predictions on target receiver surfaces. The optical analysis is performed using the code CIRCE2. These analyses account for finite sun size with limb darkening, concentrator surface slope and position errors, concentrator petal thermal deformation, gaps between petals, and the shading effect of the receiver support struts. The receiver spatial flux distributions are then combined with concentrator shadowing predictions. Geometric shadowing patterns are traced from the concentrator to the target receiver surfaces. These patterns vary ...

Energy Technology Data Exchange (ETDEWEB)

This paper, firstly, introduces the background in developing a high quality water supply system, in which the drinking water system is isolated inside a building. Results of questionnaire on the high quality service water are illustrated. The results of questionnaire have revealed that the high quality service water is extremely interested. Then, are described the target quality of high quality water, the constitution of high quality water supply system, the treatment process, the measures to secure safety and sanitary, and the method of maintenance. The high quality water is produced through the activated charcoal absorption treatment, membrane treatment, ozonation, cooling, mineral addition, and disinfection of city water. Furthermore, application examples of this system adopted to a department store and a bachelor apartment house are introduced. For the high quality water supply ...

J-STORE (Japan)

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UK PubMed Central (United Kingdom)

All microRNA (miRNA) target—finder algorithms return lists of candidate target genes. How valid is that output in a biological setting? Transcriptome analysis has proven to be a useful approach...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Greenhouse gas mitigation strategies are generally considered costly with world leaders often engaging in debate concerning the costs of mitigation and the distribution of these costs between different countries. In this paper, the analyses and results of the design of a 100% renewable energy system by the year 2050 are presented for a complete energy system including transport. Two short-term transition target years in the process towards this goal are analysed for 2015 and 2030. The energy systems are analysed and designed with hour-by-hour energy system analyses. The analyses reveal that implementing energy savings, renewable energy and more efficient conversion technologies can have positive socio-economic effects, create employment and potentially lead to large earnings on exports. If externalities such as health effects are included, even more benefits can be expected. 100% ...

Energy Technology Data Exchange (ETDEWEB)

By using megaelectronvolt /sup 4/He ion backscattering techniques and transmission electron microscopy, the authors have investigated the interactions of ion beams with thin film structures in a number of silicide-forming systems. The mixed layer was found to be an equilibrium compound for near-noble metals and an amorphous phase for refractory metals. Differences in behavior have also been observed in near-noble metal systems. For palladium, the Pd/sub 2/Si phase grew with ion dose and remained crystalline up to high dose. For nickel, the compound Ni/sub 2/Si was formed initially and became amorphous on prolonged irradiation. All the results indicate the significance of atomic mobility at target temperatures in determining the phase formation and in explaining the sensitivity of the silicides to ion bombardment.

Energy Technology Data Exchange (ETDEWEB)

This article discusses the use of five-core cables to provide utility customers with the best possible prerequisites for trouble-free operation of electrical installations and equipment. The TN-S system in buildings and the new TN-S-five-core house-connection cable for connections between the mains distribution point and buildings is introduced. The long-term target of providing TN-S-systems in power distribution even as far as the local transformer is also discussed. The advantages of the system are discussed and various configurations for different types of supply are described.

Energy Technology Data Exchange (ETDEWEB)

In processes of this invention aqueous waste solutions containing a variety of mixed waste contaminants are treated to remove the contaminants by a sequential addition of chemicals and adsorption/ion exchange powdered materials to remove the contaminants including lead, cadmium, uranium, cesium-137, strontium-85/90, trichloroethylene and benzene, and impurities including iron and calcium. Staged conditioning of the waste solution produces a polydisperse system of size enlarged complexes of the contaminants in three distinct configurations: water-soluble metal complexes, insoluble metal precipitation complexes, and contaminant-bearing particles of ion exchange and adsorbent materials. The volume of the waste is reduced by separation of the polydisperse system by cross-flow microfiltration, followed by low-temperature evaporation and/or filter pressing. The water produced as filtrate is discharged if it meets a specified ...

Energy Technology Data Exchange (ETDEWEB)

Glass produced during the Purex 4 campaigns of the Integrated Defense Waste Processing Facility (DWPF) Melter System (IDMS) and the 774 Research Melter contained a lower fraction of sludge components than targeted by the Product Composition Control System (PCCS). Purex 4 glass was more durable than the benchmark (EA) glass, but less durable than most simulated SRS high-level waste glasses. Also, Purex 4 glass was considerably less durable than predicted by the algorithm which will be used to control production of DWPF glass. A melter run was performed using the 774 Research Melter to determine if the initial PCCS target composition determined for Purex 4 would produce acceptable glass whose durability could be accurately modeled by Hydration Thermodynamics. Reagent grade oxides and carbonates were added to Purex 4 melter feed stock to simulate a higher sludge loading. Each canister of glass produced was ...

Energy Technology Data Exchange (ETDEWEB)

We have studied the impact of overexpression of an intracellular signaling protein, integrin-linked kinase (ILK), on the survival and function of encapsulated islet tissue used for the treatment of type 1 diabetes. The dimensions of the encapsulated tissue can impact the stresses placed on the tissue and ILK overexpression shows the ability to extend function of dissociated cells as well as intact islets. These results suggest that lost cell-extracellular matrix interactions in cell encapsulation systems can lead to decreased insulin secretion and ILK signaling is a target to overcome this phenomenon. (communication)

British Library Electronic Table of Contents (United Kingdom)

Anxiety disorders are a highly prevalent and disabling class of psychiatric disorders. This review focuses on new directions in neurobiological research and implications for the development of novel psychopharmacological treatments. Neuroanatomical and neuroimaging research in anxiety disorders has centered on the role of the amygdala, reciprocal connections between the amygdala and the prefrontal cortex, and, most recently, alterations in interoceptive processing by the anterior insula. Anxiety disorders are characterized by alterations in a diverse range of neurochemical systems, suggesting ample novel targets for drug therapies. Corticotropin-releasing factor (CRF) concentrations are elevated in a subset of anxiety disorders, which suggests the potential utility of CRF receptor antagoni...

Wastenet

... A better understanding of the links between nutrients, the gut microbiome and the intestinal immune system is likely to pave the way to the development of innovative approaches that target activation of specific immunological pathways for promoting the hostrsquo;s gut defense. Such knowledge should positively impact on the development of vaccine formulations and intervention strategies for improved control of enteric infections in developing countries. Registration fees # The Registration Fee is $715.00 on and before September 7, 2011. # After September 7, 2011, the ...

International Nuclear Information System (INIS)

The fusion excitation function for the radioactive projectile "8 Li on a "2"0"8 Pb target has been measured at energies near the Coulomb barrier. The results show that in the considered energy interval, the evaporation of four neutrons is the most relevant mechanism. However, at the highest energies used in the experiment, the Sn channel begins to appear. The preliminary experimental cross sections show a good agreement with the predictions of a simple evaporation calculation using the code PACE. (Author) 16 refs., 1 tab., 4 figs.

CERN Document Server

In this paper we dealt with the comparison and linking between lexical resources with domain knowledge provided by ontologies. It is one of the issues for the combination of the Semantic Web Ontologies and Text Mining. We investigated the relations between the linguistics oriented and domain-specific semantics, by associating the GO biological process concepts to the FrameNet semantic frames. The result shows the gaps between the linguistics-oriented and domain-specific semantics on the classification of events and the grouping of target words. The result provides valuable information for the improvement of domain ontologies supporting for text mining systems. And also, it will result in benefits to language understanding technology.

Science.gov (United States)

Kong-Ming Wu (Corresponding author) The application of recombinant DNA technology has resulted in many insect-resistant varieties by genetic engineering (GE). Crops expressing Cry toxins derived from Bacillus thuringiensis (Bt) have been planted worldwide, and are an effective tool for pest control. However, one ecological concern regarding the potential effects of insect-resistant GE plants on non-target organisms (NTOs) has been continually debated. In the present study, we briefly summarize the data regarding the development and commercial use of transgenic Bt varieties, elaborate on the procedure and methods for assessing the non-target effects of insect-resistant GE plants, and synthetically analyze the related research results, mostly those published between 2005 and 2010. A mass of laboratory and field studies have shown that the currently available Bt crops have no direct detrimental effects on NTOs due to their narrow spectrum of ...

International Nuclear Information System (INIS)

Environmental targets and saving energy have become ones of the world main concerns over the last years and it will increase and become more important in a near future. The world population growth rate is the major factor contributing for the increase in global pollution and energy and water consumption. In 2005, the world population was approximately 6.5 billion and this number is expected to reach 9 billion by 2050 [United Nations, 2008. (www.un.org), accessed on July]. Water supply systems use energy for pumping water, so new strategies must be developed and implemented in order to reduce this consumption. In addition, if there is excess of hydraulic energy in a water system, some type of water power generation can be implemented. This paper presents an optimization model that determines the best hourly operation for 1 day, according to the electricity tariff, for a pumped storage system with water ...

Energy Technology Data Exchange (ETDEWEB)

As a part of the WE-NET project, the tanker for liquid hydrogen transport was studied. In fiscal 1996, some experiments and numerical analyses were proposed which are necessary to solve technological issues extracted in fiscal 1995 for heat insulation structure. The issue was roughly classified into vacuum and non-vacuum insulation, and their basic functions and required performance were arranged. Boil-off rate of 0.2-0.4%/d was targeted. The insulation system which applies polyurethane form (PUF) to tank surfaces and injects atmospheric N2 gas into the surrounding hold space, could achieve the targeted insulation performance by PUF of 1m in thickness. The system of vacuum panel insulation and atmospheric N2 gas injection into a hold space required the panel of 500mm in thickness because of the large effect of metallic outer panel material. The system of vacuum hold and PUF panels ...

Science.gov (United States)

In this paper, we introduce a new recursive neural network model able to process directed acyclic graphs with labelled edges. The model uses a state transition function which considers the edge labels and is independent both from the number and the order of the children of each node. The computational capabilities of the new recursive architecture are assessed. Moreover, in order to test the proposed architecture on a practical challenging application, the problem of object detection in images is also addressed. In fact, the localization of target objects is a preliminary step in any recognition system. The proposed technique is general and can be applied in different detection systems, since it does not exploit any a priori knowledge on the particular problem. Some experiments on face detection, carried out on scenes acquired by an indoor camera, are reported, showing very promising results. PMID:16181770

Energy Technology Data Exchange (ETDEWEB)

Reliable facility of cyclotron-based real time neutron radiography system has been developed and applied to some industrial components. The equipment for neutron fluoroscopy is based on a sub-compact cyclotron and a LiF/ZnS (Ag) fluorescent screen viewed by a silicon intensifier target TV camera. The real time image is monitored on a CRT, recorded with a standard video recorder and processed by a digital image processor. The effectiveness of our real time neutron radiograph has been demonstrated to be applicable to not only the dynamic observation but also the magnifying and stereoscopic observation of fluoroscopic images.

British Library Electronic Table of Contents (United Kingdom)

The recent breakthrough in the generation of rat embryonic stem cells (rESCs) opens the door to application of gene targeting to create models for the study of human diseases. In addition, the in vitro differentiation system from rESCs into derivatives of three germ layers will serve as a powerful tool and resource for the investigation of mammalian development, cell function, tissue repair, and drug discovery. However, these uses have been limited by the difficulty of in vitro differentiation. The aims of this study were to establish an in vitro differentiation system from rESCs and to investigate whether rESCs are capable of forming terminal-differentiated cardiomyocytes. Using newly established rESCs, we found that embryoid body (EB)-based method used in mouse ESC (mESC) differentiation...

Energy Technology Data Exchange (ETDEWEB)

To more accurately measure fluorescent signals from microarrays, we calibrated our acquisition and analysis systems by using groundtruth samples comprised of known quantities of red and green gene-specific DNA probes hybridized to cDNA targets. We imaged the slides with a full-field, white light CCD imager and analyzed them with our custom analysis software. Here we compare, for multiple genes, results obtained with and without preprocessing (alignment, color crosstalk compensation, dark field subtraction, and integration time). We also evaluate the accuracy of various image processing and analysis techniques (background subtraction, segmentation, quantitation and normalization). This methodology calibrates and validates our system for accurate quantitative measurement of microarrays. Specifically, we show that preprocessing the images produces results significantly closer to the known ground-truth for these samples.

British Library Electronic Table of Contents (United Kingdom)

This study focuses on comparing reports of nicotine withdrawal, craving, and depressive symptoms obtained using an Interactive Voice Response (IVR) system and several questionnaires. As part of a smoking cessation trial, daily reports of withdrawal, craving, and negative mood were collected using an IVR system for 7 days after participants attempted to quit smoking, and several pencil and paper questionnaires (i.e., the Minnesota Nicotine Withdrawal Scale, the Questionnaire on Smoking Urges, and the Center for Epidemiological Studies-Depression) were completed a week after the target quit date. The sample was composed of 378 daily smokers. Moderate to high correlations were found between the research questionnaires obtained at the end of the week and the corresponding daily IVR reports of ...

Energy Technology Data Exchange (ETDEWEB)

The staring point of the project was to design and construct, by taking the silvicultural point of view into account, a harvesting and processing system especially for energy-wood, containing manually driven bundling harvester, automatizing of the harvester, and automatized loading. The equipment forms an ideal method for entrepreneur`s-line harvesting. The target is to apply the system also for owner`s-line harvesting. The profitability of the system promotes the utilization of the system in both cases. The objectives of the project were: to construct a test equipment and prototypes for all the project stages, to carry out terrain and strain tests in order to examine the usability and durability, as well as the capacity of the machine, to test the applicability of the Eko-Log system in simultaneous harvesting of energy and pulp woods, and to start the marketing ...

Energy Technology Data Exchange (ETDEWEB)

A method of abrasion testing according to ASTM C 704-76 a is presented for steel fibre concrete mortar, fusion-cast basalt and a surface coating material and results of practical interest are mentioned. Due to the high technical demands on these materials and their specific fields of application, the very first test already supplied interesting findings. From the user's point of view, the method is an interesting alternative to the common test methods, e.g. according to DIN 52 108 (wheel test according to Boehme). In English-speaking countries, testing according to ASTM is often mandatory in the refractory industry in order to assure constant quality of refractory materials after setting. The method is characterized by good comparability and high accuracy of measurement. Only the test piece is exchanged while the test conditions remain constant, so that accurate information on the material studied is obtained.

National Aeronautics and Space Administration (NASA)

GPM moves from the clean room to the test chamber on a dolly without wheels. Compressed air is pumped out under airpads that float the Spacecraft on a bed of air. nThe wind generated when the centrifuge moves at its maximum speed are more than 200 mph - that's tornado speed. But since they move with the centrifuge the satellites tested only feel 20 mph winds. nLeaning outward at 45 degrees for one test orientation, GPM comes within 28 inches of the wall. When lifted onto the platform it cleared the ceiling by only five inches. nNatural audio only. nVideo Credit: Brooke Harris n

British Library Electronic Table of Contents (United Kingdom)

The determination of residual stress (RS) in case-hardened steel gear truck synchronisers coated with thermal sprayed molybdenum was carried out using neutron and synchrotron X-ray diffraction. Two samples with different coating thicknesses (about 120 ?m and 1.4 mm) and different steel substrates (16MnCr5 and SAE4140, respectively) were investigated. Microanalysis revealed substantial porosity in both samples and some debonding was observed between the thin coating and the substrate. The bulk hardness of the SAE 4140 proved to be much higher than the 16MnCr5 and the surface case-hardening increased it by a further 20%. The full three-dimensional stress depth-profile was determined by neutron diffraction (ND) in both the coatings and the substrates, while synchrotron radiation allowed a dep...

Energy Technology Data Exchange (ETDEWEB)

A 1984 American Association of the Academy of Sciences study of more than 150 successful science in-service programs developed a list of their characteristics, which included: Strong academic component in mathematics, science, and communications, focused on enrichment rather than remediation; academic subjects taught by teachers who are highly competent in the subject matter and believe that students can learn the materials; heavy emphasis on the applications of science and mathematics and careers in these fields; integrative approach to teaching that incorporates all subject areas, hands-on opportunities, and computers; multiyear involvement with students; recruitment of participants from all relevant target populations; opportunities for in-school and out-of-school learning experiences; parental involvement and development of base of community support; specific attention to removing educational inequalities related to race and gender; involvement of professionals ...

British Library Electronic Table of Contents (United Kingdom)

Abstract MicroRNAs (miRNAs) play important roles in global gene regulation. Researchers in recombinant protein production have proposed miRNAs as biomarkers and cell engineering targets. However, miRNA expression remains understudied in Chinese Hamster Ovary cells, one of the most commonly used host cell systems for therapeutic protein production. To profile highly conserved miRNA expression, we used the miRCURY- miRNA array for screening miRNAs in CHO cells. The selection criteria for further miRNA profiling included positive hybridization signals and experimentally validated predicted regulatory targets. On the basis of screening, we selected 16 miRNAs for quantitative RT-PCR profiling. We profiled miR expression in parental CHO DG44 and CHO K1 cell lines as well as four recombinant DG44...

Science.gov (United States)

Magnetic particles have become very promising materials for drug delivery. However, preparation of magnetite particles with high surface area, biocompatibility, strong magnetic response, and suitable particle size still remains a major challenge. In this report, magnetite nanocrystal clusters with high surface areas were fabricated through a solvothermal process by introducing ammonium acetate as a porogen and trisodium citrate as a surface modification agent. The porosity, which was controlled by the reactant concentration, has been investigated in detail. The surface area of the nanocrystal clusters was as high as 141?m(2) g(-1) . Ibuprofen, as a model drug, was entrapped into the magnetite carriers. The interfacial interaction between the carboxylic groups on the drug molecules and the carboxylate groups on the carriers enhanced the loading efficiency. Low cytotoxicity in MCF-7 cell and in vitro constant drug release behavior combined with the high drug loading efficiency and high ...

Energy Technology Data Exchange (ETDEWEB)

Based on the tried and proven 32/40 diesel engine MAN B and W Diesel AG has developed a dual fuel gas engine covering a rate from 2.4 to 7.2 MW for stationary application in cogeneration and power stations. This paper reports the salient points of the 32/40 DG development project from the concept phase through to prototype testing. To reach the targets a dual fuel prechamber combustion system was developed using an externally arranged, cylinder individual gas admission for the main combustion chamber and a pilot fuel injection to the prechamber. Due to the high thermal and mechanical load sustaining capability of the strong-built heavy fuel diesel engine, bmep (19.9 bar) and efficiency (42.6%) in excess of the targets were achieved with a more than satisfactory life of components. Moreover, the NO{sub x} limit of 500 mg/m{sup 3} as specified in the German TA Luft was successfully met.

International Nuclear Information System (INIS)

The performance of a convolution/superposition based treatment planning system depends on the ability of the dose calculation algorithm to accurately account for physical interactions taking place in the tissue, key components of the linac head and on the accuracy of the photon beam model. Generally the user has little or no control over the performance of the dose calculation algorithm but is responsible for the accuracy of the beam model within the constraints imposed by the system. This study explores the dosimetric impact of limitations in photon beam modeling accuracy on complex 3D clinical treatment plans. A total of 70 photon beam models was created in the Pinnacle(TM) treatment planning system. Two of the models served as references for 6 MV and 15 MV beams, while the rest were created by perturbing the reference models in order to produce specific deviations in specific regions of the calculated dose profiles ...

UK PubMed Central (United Kingdom)

Human antibodies targeting prostate cancer cell surface epitopes may be useful for imaging and therapy. The objective of this study was to evaluate the tumor targeting of an internalizing human...Full Text Available

UK PubMed Central (United Kingdom)

Computational prediction of microRNA targets remains a challenging problem. The existing rule-based, data-driven and expression profiling approaches to target prediction are mostly approached from the...Full Text Available

International Nuclear Information System (INIS)

'Full text:' The use of fuel cell technology in military applications will depend on safe, high energy density systems being developed. An important part of using this technology is also the development of alternative hydrogen producing fuels with high energy densities and are easy to transport. Fuel cells are now a very large R and D effort for several military applications around the world. The major reason is because of the high power demands needed requires electrical energy sources that far exceed the capabilities of batteries currently being fielded for portable applications. Fuel cells are regarded as highly efficient, tactical energy converters that can be adapted for wide range of power requirements. They are potentially the lowest weight power source when coupled with batteries or capacitors to form hybrid systems. Generally electrical power is needed to support a number of applications from ultra-high power for electrical pulses ...

Energy Technology Data Exchange (ETDEWEB)

This thesis describes the analysis of the semileptonic decay D{sup 0} {yields} {bar K}{sup 0} {pi}{sup -} {mu}{sup +}{nu} using FOCUS data. FOCUS is a fixed target experiment at Fermilab that studies the physics of the charm quark. Particles containing charm are produced by photon-gluon fusion from the collision of a photon beam on a BeO target. The experiment is characterized by excellent vertex resolution and particle identification. The spectrometer consists of three systems for track reconstruction (two silicon systems and one multiwire proportional chamber system) and two magnets of opposite polarity. The polarity of the magnet is such that the events of e{sup +}e{sup -} pairs produced in the target (which constitutes the main background) travel through a central opening in the detectors without interactions. Particle momentum is measured from the ...

UK PubMed Central (United Kingdom)

In an effort to develop octahedral metal complexes as chemotherapeutic and diagnostic agents targeted to DNA, it is critical to optimize the properties of their cellular uptake. Appending d-octaarginine...Full Text Available

Science.gov (United States)

... L. Sutton. 2000. Is the aquatic weed hygrophila, Hygrophila polysperma (Polemoniales: Acanthaceae), a suitable target for classical biological ... ...

Science.gov (United States)

By W. Wayne Scott. Langley Research Center. SUMMARY. Thin- and thick-target bremsstrahlung spectra are presented for electron energies up to 7.0 MeV. ...

International Nuclear Information System (INIS)

We have investigated the nanocrystalline microstructure and the hard magnetic properties of Sm(Co_0_._7_2_5Fe_0_._1Cu_0_._1_2Zr_0_._0_4B_0_._0_1_5)_7_._4 melt-spun ribbons. The coercivity (H_c) of the as-spun ribbons increased with the wheel surface speed from 2.8kOe for 10m/s to 14.5kOe for 40m/s. The post-annealing of the melt-spun ribbons from 700 to 900 deg. C for 10min did not lead to a substantial increase of H_c. However, after isothermal aging at 820 deg. C and subsequent slow cooling (0.5 deg. C/min) to 120 deg. C, H_c increased from 2.8 to 10.9kOe for 10m/s, while it decreased from 14.5 to 13.5kOe for 40m/s ribbons. The grain size of the melt-spun ribbon reduced with structural transformation from 2:17H (Th_2Ni_1_7-hexagonal type) to 1:7H (TbCu_7-hexagonal type) as the wheel surface speed was increased. Three-dimensional atom probe analysis showed a boron enriched precipitate at the grain boundaries in the as-spun ribbons, which acts ...

Energy Technology Data Exchange (ETDEWEB)

Detecting a camouflaged target in a visually noisy background depends on the ability of the observer to discriminate the target from the surrounding terrain. Visible laser irradiation at less than damage levels can act as a masking source by compromising or reducing the observer's ability to resolve differences in the visual scene. Previous research has examined this concept by investigating laser flash effects on: acuity (size discrimination); tracking (motion discrimination); visual sensitivity (color); and contrast sensitivity functions (luminance contrast). In all cases, flashes from continuous-wave (CW) sources have proven more effective visually than pulsed (Q-switched) sources, when compared on peak-energy criteria (i.e., MPE), even though Q-switched lasers induce damage at lower energy doses. Additionally, the inherent safety of ultra-short laser pulses has been questioned. Past animal research has shown that, on the measures ...

International Nuclear Information System (INIS)

A quantitative comparison of tissue distribution and excretion of an orally administered sublethal dose of [3H]diacetoxyscirpenol (anguidine) was made in rats and mice 90 min, 24 hr, and 7 days after treatment. Total recoveries of 95-100% were obtained. Approximately 90% of the dose was excreted in urine and feces during the first 24 hr with a feces:urine ratio of about 1:4.5 in both species. Carcass and tissue radioactivity dropped rapidly during the first 24 hr but remained relatively constant at low, but detectable, levels over the course of the experiment. Few substantive interspecies differences were noted in tissue distribution. At 90 min the highest percentage of dose was in tissues involved in sequestering diacetoxyscirpenol because of high body water/lipid content or the absorption, metabolism, or excretion of the toxin. The rank order of these tissues was generally stable over the course of the experiment. When data were expressed as specific radioactivity instead, the ...

Energy Technology Data Exchange (ETDEWEB)

In the Ti-Si-C and Ti-Si-C-N systems, metastable layers were precipitated by means of non-reactive magnetron sputtering of hot-pressed two-phase TiC/SiC and TiN/SiC targets with 20 mole% and 50 mole% SiC. The preparation parameters were varied as follows: ion bombardment during precipitation (bias sputtering), substrate temperature, and annealing times when annealing amorphous 50%:50% TiC/SiC and 50%:50% TiN/SiC layers. Sputtering of targets containing 20% SiC was found to result in monophase fcc layers (NaCl structure). This was documented on the basis of X-ray and electron diffraction patterns. Direct precipitation of targets with 50 mole% SiC resulted in amorphous layers. Increasing the ion bombardment during accretion, raising the substrate temperature, and annealing amorphous 50%:50% TiC/SiC and 50%:50% TiN/SiC (layers precipitated directly) resulted in the crystallization of TiC and TiN ...

Science.gov (United States)

An enantiocontrolled route to aziridinomitosenes had been developed from l-serine methyl ester hydrochloride. The tetracyclic target ring system was assembled by an internal azomethine ylide cycloaddition reaction based on silver ion-assisted intramolecular oxazole alkylation and cyanide-induced ylide generation via a labile oxazoline intermediate (62 to 66). Other key steps include reductive detritylation of 26, methylation of the N-H aziridine 56, oxidation of the sensitive cyclohexenedione 68 to quinone 70, and carbamoylation using Fmoc-NCO. Although the aziridinomitosene tetracycle is sensitive, a range of protecting group manipulations and redox chemistry can be performed if suitable precautions are taken. A study of DNA alkylation by the first C-6,C-7-unsubstituted aziridinomitosene 11a has been carried out, and evidence for DNA cross-link formation involving nucleophilic addition to the quinone subunit is described. PMID:14677970

International Nuclear Information System (INIS)

Smoothing of laser beam non-uniformities using gas jets has been studied. The experiment has been performed with the PALS (Prague Asterix Laser System) laser working at 0.44 ?m with an intensity of about 1015 W/cm2. The laser beam has been split in two by a prism thus creating an artificial large-scale non-uniformity (? 90 ?m). We recorded time resolved and static images of laser-gas jet interaction with and without an Al target. Multi 1-dimensional and 2-dimensional simulations show that such interaction acts redistributing the over-intensities over larger surface. This effect has to be attributed to ionization processes with consequent laser beam refraction. Results show that Argon gas jet produces a strong refraction of the laser beam thus strongly reducing the initial two spots separation. (authors)

Energy Technology Data Exchange (ETDEWEB)

The energy spectra and angular distributions of proton emission in a reaction of {sup nat}Fe(n,xp) at a neutron energy of 14.6 MeV are measured by the University of Science and Technology of China multitelescope system. The double-differential cross sections of 16 reaction angles from 25 to 164.5 deg are obtained in this measurement. The statistical errors are reduced largely because of the thick target used. The angular distributions show a slightly energy-dependent forward-backward asymmetry. The angle-integrated proton spectrum is compared with theoretical calculations and other results. The total proton-emission cross section is in fair agreement with the prediction and evaluation.

CERN Document Server

A time-reversal-violating spin-correlation coefficient in the total cross section for polarized neutrons incident on a tensor rank-2 polarized target is calculated by assuming a time-reversal-noninvariant, parity-conserving ``five-fold" interaction in the neutron-nucleus optical potential. Results are presented for the system $n + {^{165}{\\rm Ho}}$ for neutron incident energies covering the range 1--20 MeV. From existing experimental bounds, a strength of $2 \\pm 10$ keV is deduced for the real and imaginary parts of the five-fold term, which implies an upper bound of order $10^{-4}$ on the relative $T$-odd strength when compared to the central real optical potential.

British Library Electronic Table of Contents (United Kingdom)

The aim of this study is to compare, from an environmental point of view, different alternatives for the management of municipal solid waste generated in the town of Castellon de la Plana (Spain). This town currently produces 207ton of waste per day and the waste management system employed today involves the collection of paper/cardboard, glass and light packaging from materials banks and of rest waste at street-side containers. The proposed alternative scenarios were based on a combination of the following elements: selective collection targets to be accomplished by the year 2015 as specified in the Spanish National Waste Plan (assuming they are reached to an extent of 50% and 100%), different collection models implemented nationally, and diverse treatments of both the separated biodegrad...

British Library Electronic Table of Contents (United Kingdom)

The need for safe food products has motivated food scientists and industry to find novel technologies for antimicrobial delivery for improving food safety and quality. Controlled release packaging is a novel technology that uses the package to deliver antimicrobials in a controlled manner and sustain antimicrobial stress on the targeted microorganism over the required shelf life. This work studied the effect of controlled release of nisin to inhibit growth of Micrococcus luteus (a model microorganism) using a computerized syringe pump system to mimic the release of nisin from packaging films which was characterized by an initially fast rate and a slower rate as time progressed. The results show that controlled release of nisin was strikingly more effective than instantly added (?formulated...

Energy Technology Data Exchange (ETDEWEB)

MRI is a powerful diagnostic modality of expanding availability. Equipment and installation amount to nearly $2M per site. An important component of diagnostic efficacy is not just equipment costs but also replacement costs, which for x-ray CT amount to 14-20% of the purchase cost per year; and in the early years of that technology reached 30-50%. The authors show how design choices made during the RandD stages of MRI development have allowed them to improve system performance parameters such as data reconstruction, archiving and display speeds, computational capabilities, operator interfaces, imaging sequence flexibility and signal-to-noise levels. Over the last four years these improvements have been made at a retrofit cost well below the target of 6-7% of the purchase price per year.

British Library Electronic Table of Contents (United Kingdom)

A model is developed to represent mechanical strain, stress-enhanced dissolution, and shear dilation as innately hysteretic and interlinked processes in rough contacting fractures. The model is incorporated into a numerical simulator designed to examine permeability change and thermal exchange in chemically active and deformable fractured reservoirs. A candidate engineered geothermal reservoir system (EGS) is targeted. The mechanistic model is able to distinguish differences between the evolution of fluid transmission characteristics of (1) small scale, closely spaced fractures, and (2) large-scale, more widely spaced fractures. Alternate realizations of fracture frequency and scale, exhibiting identical initial bulk permeability, lead to significantly different conclusions regarding perme...

British Library Electronic Table of Contents (United Kingdom)

Proton pump inhibitors are highly successful in treating gastroesophageal reflux disease, but a significant proportion of patients have persistent symptoms from weakly or nonacidic reflux. Transient lower esophageal sphincter relaxation (TLESR) represents the dominant mechanism of gastroesophageal reflux and has therefore become the most intensely investigated therapeutic target. The triggering of TLESR involve the vagal pathways and the ?-aminobutyric type B (GABA(B)) and metabotropic glutamate type 5 (mGluR5) receptors. Baclofen is a GABA(B) receptor agonist that is effective in inhibiting TLESR and reducing the number of reflux episodes, but is associated with significant central nervous system (CNS) side effects. The newer GABA(B) agonists, such as AZD9343 and AZD3355, and mGluR5 antag...

Energy Technology Data Exchange (ETDEWEB)

The Triangle Universities Nuclear Laboratory (TUNL)--a collaboration of Duke University, North Carolina State University, and the University of North Carolina at Chapel Hill--has had a very productive year. This report covers parts of the second and third year of a three-year grant between the US Department of Energy and the three collaborating universities. The TUNL research program focuses on the following areas: precision test of parity-invariance violation in resonance neutron scattering at LANSCE/LANL; parity violation measurements using charged-particle resonances in A = 20--40 targets and the A = 4 system at TUNL; chaotic behavior in the nuclei {sup 30}P and {sup 34}Cl from studies of eigenvalue fluctuations in nuclear level schemes; search for anomalies in the level density (pairing phase transition) in 1f-2p shell nuclei using GEANIE at LANSCE/LANL; parity-conserving time-reversal noninvariance tests using {sup 166}Ho resonances at ...

Energy Technology Data Exchange (ETDEWEB)

Olive field is oil productive from a thin stratigraphically trapped sandstone within the Upper Cretaceous lower Tuscaloosa Formation. The discovery of Olive in 1981 led to renewed interest in the Mid-Dip Tuscaloosa Trend that continues today. Discovery and development was based on the correlation of the B sandstone to a mappable soft seismic event at a depth of 10,500 ft. The field was developed by 25 wells on 40-acre spacing. Olive has been waterflooded since 1983 and is a target for enhanced recovery using carbon dioxide. A total of 7.5 million stock tank bbl or approximately 75% of the original oil in place is estimated to be recoverable by conventional and enhanced recovery methods. The B sandstone was deposited by a northwest to southeast-flowing high-sinuosity meandering river system. Point bar, channel, and channel abandonment deposits are present. The point bar formed from the lateral migration of the river system ...

International Nuclear Information System (INIS)

It needs accurate estimation of radiation level for verifying machinery and cable in Nuclear Power Plant. Therefore, in this study, we used ESR(Electron Spin Resonance) system for estimate dose of Alanine dosimeter. Alanine/ESR dosimetry, already known as a dosimetric method in medical and industrial field, was applied to estimate dose quantity at cable locations within a nuclear power plant as a part of equipment qualification program. Alanine/ESR dosimetry of absorbed dose range is 1 - 100 KGy. The alanine dosimeter is not significantly affected by temperature and fading is limited to 1% per year. The alanine dosimeters were fixed on the targeted cable or nearest position to measure dose quantity to get accurate value. Alanine dosimeters were scanned by commercially used two different ESR systems, e-scan and EMX series for alanine dosimeters. To estimate more accurate dose, two environmental correction factors, ...

International Nuclear Information System (INIS)

The Four years of the IMPACT, 'Integrated Modular Plant Analysis and Computing Technology', project Phase 1 have been completed. The verification study of Severe Accident Analysis Code SAMPSON prototype developed in Phase 1 was conducted in two steps. First, each analysis module was run independently and analysis results were compared and verified against separate-effect test data with good results. Second, with the Simulation Supervisory System, up to 11 analysis modules were executed concurrently in the parallel environment (currently, NUPEC uses IBM-SP2 with 72 process elements), to demonstrate the code capability and integrity. The target plant was Surry as a typical PWR and the initiation events were a 10-inch cold leg failure. The analysis is divided to two cases; one is in-vessel retention analysis when the gap cooling is effective (In-vessel scenario test), the other is analysis of phenomena event is extended to ex-vessel due to the ...

Energy Technology Data Exchange (ETDEWEB)

Threat characterization is a key component in evaluating the threat faced by control systems. Without a thorough understanding of the threat faced by critical infrastructure networks, adequate resources cannot be allocated or directed effectively to the defense of these systems. Traditional methods of threat analysis focus on identifying the capabilities and motivations of a specific attacker, assessing the value the adversary would place on targeted systems, and deploying defenses according to the threat posed by the potential adversary. Too many effective exploits and tools exist and are easily accessible to anyone with access to an Internet connection, minimal technical skills, and a significantly reduced motivational threshold to be able to narrow the field of potential adversaries effectively. Understanding how hackers evaluate new IT security research and incorporate significant new ideas into ...

Energy Technology Data Exchange (ETDEWEB)

Short communication.

Science.gov (United States)

In early 2006 we designed and built low energy consumption, pump-operated system, for dosing of the liquid nutrient in the summer 2006 season. This operated successfully, and the system was used again during the 2007 and 2008 seasons for dosing. During the early winter period, 2008, laboratory tests were made of the liquid nutrient pump system, and it was noted that small amounts of air were being entrained on the suction side of the pump, during conditions when the inlet pressure was low. It was believed that this was the cause of diurnal fluctuations in the flow supplied, characteristic of the 2007 year flow data. Replacement of '0' rings on the inlet side of the pumps was the solution to this problem, and when tested in the field during the summer season, the flow supplied was found to be stable. A decision was made by the IKERT committee at the meeting of 20th to 21st May 2008 (held in Coeur ...

Energy Technology Data Exchange (ETDEWEB)

The U.S. Department of Energy (DOE) and the U.S. Council for Automotive Research (composed of automakers Ford, General Motors, and Chrysler) announced in January 2002 a new cooperative research effort. Known as 'FreedomCAR' (derived from 'Freedom' and 'Cooperative Automotive Research'), it represents DOE's commitment to developing public/private partnerships to fund high-risk, high-payoff research into advanced automotive technologies. Efficient fuel cell technology, which uses hydrogen to power automobiles without air pollution, is a very promising pathway to achieving the ultimate vision. The new partnership replaces and builds upon the Partnership for a New Generation of Vehicles initiative that ran from 1993 through 2001. The Advanced Power Electronics and Electric Machines (APEEM) subprogram within the FreedomCAR and Vehicle Technologies Program provides support and guidance for many cutting-edge automotive ...

International Nuclear Information System (INIS)

With the advent of intensity-modulated radiation therapy (IMRT), the inclusion of heterogeneity corrections is further complicated by the conformal delivery of many small beams forming steep dose gradients. Radiation treatment planning has evolved to take into account even small changes in tissue density so that the dose to tumor can be further optimized. However, different treatment planning systems incorporate different heterogeneity correction algorithms, and it is unclear whether any of these algorithms are superior to others in terms of accurately predicting delivered radiation doses relative to measurement in a clinical setting. The purpose of this study was to determine the accuracy of heterogeneity dose calculations from two widely used IMRT treatment planning systems (Pinnacle and Corvus) against measurement. These two systems handle heterogeneity dose corrections by means of a collapsed-cone convolution ...

International Nuclear Information System (INIS)

An attempt is taken to explain anomalies in "9"2Mo(d, n)"9"3Tc, "9"2Mo(d, #alpha#)"9"0Nb, "9"4Mo(d, n)"9"5Tc, "9"8Mo(d, n)"9"9Tc, "9"8Mo(d, p)"9"9Mo, "9"8Mo(d, #alpha#)"9"6Nb, "1"0"0Mo(d, p)"1"0"1Mo and "1"0"0Mo(d, n)"1"0"1Tc reactions with input states having a one-particle nature. Thin films saturated with molybdenum isotopes at the approximately 1 mgxcm"-"2 surface density are used as targets. The targets are irradiated by the extracted cyclotron beam. The deuteron energy is 5-12 MeV. The reaction cross sections are determined by the activation analysis method. Quasi-stationary levels of the nucleus-deuteron system are calculated. Weak anomalies revealing in a smooth (d, #alpha#) reaction cross section on sup(92, 98)Mo nuclei, which do not necessarily correlate with anomalies in the (d, n) and (d, p) channels, are observed. The ground states of the (d, #alpha#) reaction products "9"0Nb and "9"6Nb have (8"+) and (6"+) ...

Energy Technology Data Exchange (ETDEWEB)

One of the design targets for the ITER Tokamak Exhaust Processing system is not to lose more than 10{sup -5} g h{sup -1} into the Normal Vent Detritiation System of the Tritium Plant. The plasma exhaust gas, therefore, needs to be processed in a way that an overall tritium removal efficiency of about 10{sup 8} is reached. Such a high decontamination factor can only be achieved by multistage processes. The third step of the three step CAPER process developed at the TLK is based on a so-called permeator catalyst (PERMCAT) reactor, a direct combination of a Pd/Ag permeation membrane and a catalyst bed. The PERMCAT principle is based on isotopic swamping in a counter current mode. Previous tritium experiments employing laboratory scale PERMCAT reactors have revealed decontamination factors as high as 10{sup 5} for the third CAPER step. First tritium tests with a technical scale PERMCAT reactor led to similar decontamination ...

Science.gov (United States)

Variations in skin perfusion are easily detected by laser speckle contrast maps, but a robust interpretation of the information has been lacking. We show that multiple-exposure laser speckle methods produce the same spectral information as laser Doppler methods when applied to targets with embedded moving scatterers. This enables laser speckle measurements to be interpreted more quantitatively. We do this by using computer simulation of speckle data, and by experimental measurements on Brownian motion and skin perfusion using a laser Doppler system and a multiple-exposure laser speckle system. The power spectral density measurements of the light fluctuations derived using both techniques are exactly equivalent. Dermal perfusion can therefore be measured by laser Doppler or laser speckle contrast methods. In particular, multiexposure laser speckle can be rapidly processed to generate a full-field map of the perfusion index ...

Science.gov (United States)

INTRODUCTION: This study examined the efficacy and safety of selegiline transdermal system (STS) and brief repeated behavioral intervention (BRBI) for smoking cessation in heavy smokers. We hypothesized that the quit rate of subjects who received STS and BRBI would be significantly greater than that of those who received placebo patch and BRBI. METHODS: This was a double-blind, placebo-controlled parallel-group study in which 246 men and women were randomized to receive either STS (n = 121) or placebo patch (n =125) for 9 weeks. Recruitment targeted heavy smokers, defined as individuals with self-reported use of ?15 cigarettes/day in the 30 days prior to enrollment, who had smoked cigarettes for the past 5 years, and had an expired CO level ?9 ppm during screening. RESULTS: Although STS was well tolerated, the overall results indicated that STS with BRBI was not more effective than placebo plus BRBI for smoking cessation (p = .58). Conclusions: ...

Energy Technology Data Exchange (ETDEWEB)

Heat exchangers for high and ultrahigh temperatures are a need and a precondition to realise high efficient fossil fired power plants based on the so-called Externally Fired Combined Cycle (EFCC) or the Indirect Fired Gas Turbines (IFGT). The main target of both processes is to increase the thermal efficiency of existing power plants by approximately 25% resulting in the same decrease in fuel consumption and, therefore, in the same reduction of CO{sub 2} formation. The main activities of the MPA University of Stuttgart in this project is focused on the characterisation and qualification of the structural material of the ultrahigh temperature heat exchanger (UHTHE) necessary in the above mentioned processes. The influence of the temperature and load on the material behaviour have been analysed by means of tensile tests and creep tests. The effectiveness of different coating systems and the interaction between coating system ...

Energy Technology Data Exchange (ETDEWEB)

Renewable energy systems have been suggested as appropriate technologies for developing countries for many years. But they are less attractive to low-income rural and urban populations for reasons of risk and initial capital outlay, and market penetration is usually small as a result. Technology transfer by outside intervention appears unlikely to deliver to enough people in Africa; only self propagating technologies have managed that to date. Unfortunately target populations in developing countries have little capital and are understandably reluctant to take risks. Outside interests see little likelihood of profit and have already demonstrated reluctance to invest in many developing countries. Benefit from technology relies on continued use after purchase and is rightly associated with reliability and availability. Mean time to repair may be a better measure of appropriateness than mean time between failures. Technology based on the idea of ...

International Nuclear Information System (INIS)

Acetylcholine and other neurotransmitters play unique trophic roles in brain development. Accordingly, drugs and environmental toxicants that promote or interfere with neurotransmitter function evoke neurodevelopmental abnormalities by disrupting the timing or intensity of neurotrophic actions. The current review discusses three exposure scenarios involving acetylcholine systems: nicotine from maternal smoking during pregnancy, exposure to environmental tobacco smoke (ETS), and exposure to the organophosphate insecticide, chlorpyrifos (CPF). All three have long-term, adverse effects on specific processes involved in brain cell replication and differentiation, synaptic development and function, and ultimately behavioral performance. Many of these effects can be traced to the sequence of cellular events surrounding the trophic role of acetylcholine acting on its specific cellular receptors and associated signaling cascades. However, for chlorpyrifos, additional ...

Science.gov (United States)

The contents of this report covers: (1) development of optimal geometries for crowned helical gears; (2) a method for their generation; (3) tooth contact analysis (TCA) computer programs for the analysis of meshing and bearing contact of the crowned helical gears; and (4) modelling and simulation of gear shaft deflection. The developed method for synthesis was used to determine the optimal geometry for a crowned helical pinion surface and was directed to localize the bearing contact and guarantee favorable shape and a low level of transmission errors. Two new methods for generation of the crowned helical pinion surface are proposed. One is based on the application of a tool with a surface of revolution that slightly deviates from a regular cone surface. The tool can be used as a grinding wheel or as a shaver. The other is based on a crowning pinion tooth surface with predesigned transmission errors. The pinion tooth surface can be generated by a computer-controlled ...

British Library Electronic Table of Contents (United Kingdom)

A series of NHC silver(I), mercury(II) and palladium(II) complexes, [(1,3-diethylbimy)6Ag4I3]I (2), [(1-benzyl-3-picolylbimy)Ag2Br2]n (3), [(1-benzyl-3-picolylbimy)HgI(CH2CN)]2 (4), {[(1-picolyl-3-npropylbimy)2Hg][Hg2I6]}n (5) and [(1,3-dipicolylbimy)PdCl]Cl (6), as well as one anionic complex [1,3-diethylbimidazolium]2[HgI4] (1) (bimy=benzimidazol-2-ylidene), have been prepared and characterized. Interestingly, a wind wheel-like Ag4I3 arrangement in 2 is formed, 1D polymeric chain containing 12-membered macrometallocycles and quadrangle Ag2Br2 units in 3 is generated, and the a-carbon atom of deprotonated acetonitrile ([CH2CN]-) in 4 participates in coordination with mercury(II) atom. In the crystal packings of complexes 1-6, 2D supramolecular layers or 3D supramolecular architectures are...

International Nuclear Information System (INIS)

Full text: Radiotherapy treatment planning (RTP) relies heavily on medical imaging. Until recently, the most important planning tool was the treatment simulator. The kilovoltage radiographic capabilities in a treatment simulator enabled the boundaries of treatment fields to be visualized with respect to bony anatomic landmarks. Perhaps the most important advance in treatment planning in recent years is the ability to visualize the passage of the beams with respect to a more accurate geometrical representation of the tumor and other soft tissue structures. This 'virtual simulation' uses a computer-based representation of a patient to determine the extent of the disease and the location of radiation sensitive normal tissue. Computer tomographic (CT) imaging produces a high-resolution three-dimensional representation of anatomy that can be correlated with other image sets such as magnetic resonance images (MRI) of function. Positron emission tomographic (PET) imaging is beginning to be ...

Energy Technology Data Exchange (ETDEWEB)

Development in Instrumentation and Control (I and C) technology provides more convenience and better performance, thus, adopted in many fields. To adopt newly developed technology, nuclear industry requires rigorous V and V procedure and tests to assure reliable operation. Adoption of digital system requires verification and testing of the OS for licensing. Commercial real-time operating system (RTOS) is targeted to apply to various, unpredictable needs, which makes it difficult to verify. For this reason, simple, application-oriented realtime OS is developed for the nuclear application. In this work, we show how to verify the developed RTOS at each development lifecycle. Commercial formal tool is used in specification and verification of the system. Based on the developed model, software in C language is automatically generated. Tests are performed for two purposes; one is to identify consistency ...

Science.gov (United States)

Up to the present, the generic values of the Common cause failure (CCF) event parameters have been used in most PSA projects for the Korean NPPs. However, the CCF analysis should be performed with plant specific information to meet Category II of the ASME PRA Standard. Therefore, we estimated the Alpha factor parameters of the emergency diesel generator (EDG) for Ulchin Unit 3 by using the International Common-Cause Failure data Exchange (ICDE) database. The ICDE database provides the member countries with only the information needed for an estimation of the CCF parameters. The Ulchin Unit A3, pressurized water reactor, has two onsite EDGs and one alternate AC (AAC) diesel generator. The onsite EDGs of Unit 3 and 4 and the AAC are manufactured by the same company, but they are designed differently. The estimation procedure of the Alpha factor used in this study follows the approach of the NUREG/CR-5485. Since we did not find any qualitative difference between the ...

International Nuclear Information System (INIS)

Design improvements are being incorporated into the heavy water management systems at Wolsong 2,3 and 4 to reduce the load on the vapour recovery driers and upgraders and the heavy water losses via the stack. There will also be improvements to monitor heavy water and tritium releases. This paper describes the improvements, gives background on heavy water balance mechanism, the historical trends for heavy water recovery/losses and estimated dose to the member of the public critical group resulting from the airborne and waterborne releases. The measured tritium activity levels in the heat transport system (HTS) and moderator system at Wolsong 1 are given. Using these activity levels and heavy water loss data, tritium losses from the dried and ventilated areas are estimated. A qualitative assessment of expected heavy water and tritium releases has been performed for Wolsong 2, 3 and 4. CANDU 6 plants continue to perform well ...

Energy Technology Data Exchange (ETDEWEB)

The objective of this work group was to identify obstacles to the development of better risk management practices and performance standards in the pipeline industry. An outline of developments in pipeline risk assesment management was presented, including an update of the Risk Based Design and Assessment annex and other CSA Z662 code developments. It was suggested that progress in risk management require that acceptable levels of risk and reliability need to be defined. Environmental and safety consequence analysis was recommended, as well as failure frequency estimation and assessment of distribution systems. Guidelines for Integrity Management Programs (IMPs) were reviewed. It was noted that CSA Z662 will become mandatory for sour gas in 2005 and may become mandatory for all onshore pipelines in 2007. Operating company procedures in relation to hazards with significant consequences were discussed. It was noted that companies should assess risks associated with ...

Energy Technology Data Exchange (ETDEWEB)

Heat transfer augmentation in narrow rectangular channels in a target system is a very important method to remove high heat flux up to 12 MW/m{sup 2} generated at target plates of a high-intensity proton accelerator of 1.5 GeV and 1 mA with a proton beam power of 1.5 MW. In this report, heat transfer coefficients and friction factors in narrow rectangular channels with one-sided rib-roughened surface were evaluated for fully developed flows in the range of the Reynolds number from 6,000 to 1,00,000; the rib pitch-to-height ratios (p/k) were 10,20 and 30; the rib height-to-equivalent diameter ratios (k/De) were 0.025, 0.03 and 0.1 by means of previous existing experimental correlations. The rib-roughened surface augmented heat transfer coefficients approximately 4 times higher than the smooth surface at Re=10,000, p/k=10 and k/De=0.1; friction factors increase around 22 times higher. In this case, higher heat flux up to 12 ...

Energy Technology Data Exchange (ETDEWEB)

Frictional pressure drop and heat transfer performance in a very narrow rectangular channel having one-sided constant heat flux and repeated-ribs for turbulent flow have been investigated experimentally, and their experimental correlations were obtained using the least square method. The rib pitch-to-height ratios(p/k) were 10 and 20 while holding the rib height constant at 0.2mm, the Reynolds number(Re) from 2,414 to 98,458 under different channel heights of 1.2mm, 2.97mm, and 3.24mm, the rib height-to-channel equivalent diameter(k/De) of 0.03, 0.04, and 0.09 respectively. The results show that the rib-roughened surface augments heat transfer 2-3 times higher than that of the smooth surface with the expense of 2.8-4 times higher frictional pressure drop under Re=5000-10{sup 5}, p/k=10, and H=1.2mm. Experimental results obtained by channel height, H=1.2mm shows a little bit higher heat transfer and friction factor performance than the higher channel height, H=3.24mm. The effect of fin ...

International Nuclear Information System (INIS)

This paper introduces the JNM Special Issue on the development of a first wall for the reaction chamber in a laser fusion power plant. In this approach to fusion energy a spherical target is injected into a large chamber and heated to fusion burn by an array of lasers. The target emissions are absorbed by the wall and encapsulating blanket, and the resulting heat converted into electricity. The bulk of the energy deposited in the first wall is in the form of X-rays (1.0-100 keV) and ions (0.1-4 MeV). In order to have a practical power plant, the first wall must be resistant to these emissions and suffer virtually no erosion on each shot. A wall candidate based on tungsten armor bonded to a low activation ferritic steel substrate has been chosen as the initial system to be studied. The choice was based on the vast experience with these materials in a nuclear environment and the ability to address most of the key remaining ...

UK PubMed Central (United Kingdom)

PurposeWe conducted a comparative study of Clinical Target Volume (CTV) definition of pelvic lymph nodes by multiple GU radiation oncologists looking at the levels...Full Text Available

UK PubMed Central (United Kingdom)

The technology of gene targeting through homologous recombination has been extremely useful for elucidating gene functions in mice. The application of this technology was thought impossible in the large...Full Text Available

Science.gov (United States)

... detected (and reported) as a by-product of MRM screening (MS/MS) targeted by Law or Rule ... detected (and reported) as a by-product of MRM screening (MS/MS) targeted by Law or Rule ...

UK PubMed Central (United Kingdom)

Many genetic processes depend on proteins interacting with specific sequences on DNA. Despite the large excess of nonspecific DNA in the cell, proteins can locate their targets rapidly. After initial...Full Text Available

UK PubMed Central (United Kingdom)

Considering accessibility of the 3′UTR is believed to increase the precision of microRNA target predictions. We show that, contrary to common belief, ranking by the hybridization energy or by...Full Text Available

UK PubMed Central (United Kingdom)

Operant conditioning techniques were applied to the study of how target fixations are controlled by the probability of signal occurrence. In a standard vigilance setting, gaze at three illuminable...Full Text Available

UK PubMed Central (United Kingdom)

Purposes1. To determine the optimal pelvic nodal clinical target volume for post-operative treatment of endometrial cancer. 2. To compare the DVH of different treatment planning...Full Text Available

Science.gov (United States)

... they assisted in the 2000 attack on the USS Cole? ... List the types of targets that ETA has attacked. ... was at least partially responsible for the attack. ...

Science.gov (United States)

... 1981. Retention of diphenyls, terphenyls, phenylalkanes and fluorene on graphitized thermal carbon black. Chromatographia 14:510-514. ...

Energy Technology Data Exchange (ETDEWEB)

The production of polarized negative ion beams by collisional pumping is described. Collisional pumping utilizes repeated charge changing collisions in a thick electron-spin-polarized gas or vapor target to form a polarized fast atom beam. The polarized fast atom beam is then partially converted into a polarized negative ion beam in a vapor target. Analysis is presented for a hydrogen beam passing through either a thick polarized H atom target or a thick polarized alkali target. Large polarizations and large currents may be possible.

International Nuclear Information System (INIS)

... carrier-free isotopes chemical preparation gamma spectra isotope production

International Nuclear Information System (INIS)

... range krypton 86 reactions molybdenum 92 target probability quasi-elastic

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

International Nuclear Information System (INIS)

This paper present the results of a series of calculations made to determine the "2"3"8Pu production potential of several advanced target assembly designs in the Fast Flux Test Facility (FFTF). These calculations show that by using advanced target designs the intimately mix the "2"3"7Np target material with an yttrium hydride moderator, the FFTF has the potential of producing up to 30 kg of high-quality "2"3"8Pu per year.

Energy Technology Data Exchange (ETDEWEB)

A portable fiber optic detector that senses the presence of specific target chemicals by electrostatically attracting the target chemical to an aromatic compound coating on an optical fiber. Attaching the target chemical to the coated fiber reduces the fluorescence so that a photon sensing detector records the reduced light level and activates an appropriate alarm or indicator.

International Nuclear Information System (INIS)

The implementation of a three-dimensional conformal radiotherapy facility in the radiotherapy department of the Heinrich Heine University is described. Complex radiotherapy techniques with commercially available networked systems are introduced to improve clinical work. Over 18 month we have gained clinical experience with a PHILIPS Multileaf Collimator (MLC) mounted on a SL 25 linear accelerator. For a limited period the MLC was used as a conventional blocking device. The standard MLC-shapes are controlled with a stand-alone computer system. In addition, a three-dimensional treatment planning system (3-D-TPS / TMS-Radix, Helax AB) based on convolution/superposition algorithms was recently installed. Treatment optimization is achieved using static field arrangements with complete volumetric computerized tomographic patient data for 3-D-TPS. Conformal adaptation of the 95%-isodose to the Planning Target ...

Science.gov (United States)

Low resolution and un-sharp facial images are always captured from surveillance videos because of long human-camera distance and human movements. Previous works addressed this problem by using an active camera to capture close-up facial images without considering human movements and mechanical delays of the active camera. In this paper, we proposed a unified framework to capture facial images in video surveillance systems by using one static and active camera in a cooperative manner. Human faces are first located by a skin-color based real-time face detection algorithm. A stereo camera model is also employed to approximate human face location and his/her velocity with respect to the active camera. Given the mechanical delays of the active camera, the position of a target face with a given delay can be estimated using a Human-Camera Synchronization Model. By controlling the active camera with corresponding amount of pan, tilt, and zoom, a clear ...

Energy Technology Data Exchange (ETDEWEB)

The purpose of the Utility Applications Program is to provide information and assistance to interested utilities on central station energy storage systems. Compressed air and underground pumped hydroelectric energy storage are the primary technical focus. Smaller utilities are the primary targets of this program, as they may not have resources to track and utilize new energy conservation developments. The program, initiated during this year-long period, consists of a series of tasks integrating and supporting energy storage implementation. Program management and technical coordination activities monitor the wide range of research ongoing both under government support and in industry and provide a locus for dissemination of results. Recently completed DOE demonstration studies provide the central data base and the DOE CAES and UPH Technology Program activities provide another major resource. In addition a UPH preliminary feasibility study in ...

International Nuclear Information System (INIS)

The low excitation energy spectroscopy of "8"6Sr, "8"8Sr, "8"9Sr, "8"6Rb, and "8"7Rb nuclear systems was studied via one-nucleon transfer reactions. The strontium isotopes, "8"7Sr and "8"8Sr, were used as targets in this study. Spectroscopic strengths were extracted from the measured transfer reaction cross sections and the distorted wave Born approximation (DWBA) analysis. Efforts have been made to accomplish a complete detection of spectroscopic strengths through the excitation energy region where levels can be resolved and identified. A shell model sum rule analysis is then made. Diagonal matrix elements for the effective two-nucleon interaction were deduced from empirical energy centroid. Matrix elements normalized by their empirical monopole energy was plotted against the semiclassical angle between two spins. They were compared with various analytical function forms of the effective two-nucleon interaction depending on their spins, ...

Energy Technology Data Exchange (ETDEWEB)

This presentation discussed common mechanisms for procuring wind energy in Canada. Mechanisms included renewable portfolio standards (RPSs); offsets; tax subsidies; financial subsidies; command and control mechanisms; and request for proposals (RFPs). A layered approach is required to avoid reliance on any single mechanism. RPSs require a certain minimum percentage of energy to come from renewable sources and aim to encourage the local development of renewable energy. RPSs are market-friendly and often result in the creation of tradable renewable energy credits (RECs) used for compliance purposes. RPSs work in parallel with cap and trade, baseline, and credit and carbon tax systems. RFPs target the lowest price offering, a practice which has often resulted in lower rates of return, high attrition, and a failure to attribute market prices to green attributes. It was concluded that RPSs work with a variety of policy frameworks and encourage the ...

CERN Document Server

We present metallicity estimates for seven open clusters based on spectrophotometric indices from moderate-resolution spectroscopy. Observations of field giants of known metallicity provide a correlation between the spectroscopic indices and the metallicity of open cluster giants. We use \\chi^2 analysis to fit the relation of spectrophotometric indices to metallicity in field giants. The resulting function allows an estimate of the target-cluster giants' metallicities with an error in the method of \\pm0.08 dex. We derive the following metallicities for the seven open clusters: NGC 1245, [m/H]=-0.14\\pm0.04; NGC 2099, [m/H]=+0.05\\pm0.05; NGC 2324, [m/H]=-0.06\\pm0.04; NGC 2539, [m/H]=-0.04\\pm0.03; NGC 2682 (M67), [m/H]=-0.05\\pm0.02; NGC 6705, [m/H]=+0.14\\pm0.08; NGC 6819, [m/H]=-0.07\\pm0.12. These metallicity estimates will be useful in planning future extra-solar planet transit searches since planets may form more readily in metal-rich environments.

Energy Technology Data Exchange (ETDEWEB)

The purpose of this program was to characterize Time Of Arrival Detectors (TOAD) pins response to shock loading with respect to risetime, amplitude, repeatability and consistency. TOAD pins were subjected to impacts of 35 to 420 kilobars amplitude and approximately 1 ms pulse width to investigate the timing spread of four pins and the voltage output profile of the individual pins. Sets of pins were also aged at 45{degrees}, 60{degrees}, and 80{degrees}C for approximately nine weeks before shock testing at 315 kilobars impact stress. Four sets of pins were heated to 50.2{degrees}C (125{degrees}F) for approximately two hours and then impacted at either 50 or 315 kilobars. Also, four sets of pins were aged at 60{degrees}C for nine weeks and then heated to 50.2{degrees}C before shock testing at 50 and 315 kilobars impact stress, respectively. Particle velocity measurements at the contact point between the stainless steel targets and TOAD pins were made using a Velocity ...

Energy Technology Data Exchange (ETDEWEB)

The authors propose to develop a high-energy heavy-ion experimental database and make it accessible to the scientific community through an on-line interface. This database will be searchable and cross-indexed with relevant publications, including published detector descriptions. Since this database will be a community resource, it requires the high-energy nuclear physics community's financial and manpower support. This database should eventually contain all published data from Bevalac, AGS and SPS to RHIC and CERN-LHC energies, proton-proton to nucleus-nucleus collisions as well as other relevant systems, and all measured observables. Such a database would have tremendous scientific payoff as it makes systematic studies easier and allows simpler benchmarking of theoretical models to a broad range of old and new experiments. Furthermore, there is a growing need for compilations of high-energy nuclear data for applications including stockpile stewardship, ...

Energy Technology Data Exchange (ETDEWEB)

The existence, in real-time, of transmission constraints, demand forecasting errors, generator failures, and other factors impose additional costs through the need to run more expensive generation. These costs can appear as a significant component of the wholesale price to demand served by electricity markets operated over transmission networks. In the England & Wales Pool these costs are passed through directly to supply companies. The Transmission System Operator ({open_quotes}TSO{close_quotes}) can exert significant influence on these costs through improved availability of transmission circuits and through appropriate investment, but has no incentive to do so. Since the inception of the Pool, these costs have increased in level and volatility, and have proved difficult to hedge. In response, St Clements Services were instrumental in assisting Pool members to develop an {open_quotes}Uplift Incentive Management Scheme{close_quotes} which has seen controllable ...

Energy Technology Data Exchange (ETDEWEB)

The uncoupling protein (UCP) is a proton/anion transporter found in the inner mitochondrial membrane of brown adipocyte. Although UCP has nor been detected in mitochondria from any other tissue, it shares structural and catalytic properties with several other mitochondrial carrier proteins. Although UCP was discovered only recently it is one of the most extensively studied mitochondrial carrier proteins.More recently, the mouse, rat, and human genes encoding for UCP have been isolated and sequenced. The availability of these various tools has led to several significant observations. UCP gene expression is strongly controlled at the level of transcription by signals that are activated after the stimulation of brown adipocytes by norepinephrine. The comparison of UCP gene with the genes encoding the adenine nucleotide translocator revealed the existence of structural and evolutionary homologies. Moreover, in humans the UCP gene and one form of adenine nucleotide translocator gene are ...

International Nuclear Information System (INIS)

A combination of measuring instruments, consisting of a Beta-Sedimeter and a radionuclide X-ray fluorescence instrument, is described. With the Beta-Sedimeter the C-14-radiation is measured. Through direct irradiation with photons of a Pu238-source in an ancillary irradiation chamber and energy dispersing measurement of the K- and L-radiation resp. of the excited heavy metals with the aid of a Si(Li)-semiconductor detector and a 4-channel analyzer the heavy metal concentrations of the heavy metals Zn, Cr, Ni and Pb are determined. For the determination of cadmium the indirect excitation with Am-241 and Dy-targets is described. The system produces records and operates fully automatically in a step-by-step mode with a testing cycle of 45 minutes. In connection with the process monitoring of the wastewater from a zinc plating plant during a period of 8 months the concentration of the solid material and of the metals Cr and Zn, which were ...

CERN Document Server

In a recent study of a search for enhancements from the galactic center with muons at sea level using the TUPI muon telescope, we have found several ground level enhancements (GLEs) as very sharp peaks above the count rate background. This paper reports a consistent analysis of two GLEs observed in December 2003 and detected after an up-grade of the data acquisition system, which includes a noise filter and which allows us to verify that the GLEs are not mere background fluctuations. The main target of this study is a search for the origin of the GLEs. The results show that one of them has a strong correlation with a solar flare, while the other has an unknown origin, because there is neither a satellite report of a solar flare, nor prompt X-ray emission, and nor a excess of nuclei during the raster scan where the GLE was observed. Even so, two possibilities are analyzed: the solar flare hypothesis and the gamma ray burst (GRB) hypothesis. We ...

Science.gov (United States)

The GTPases comprise a protein superfamily of highly conserved molecular switches adapted to many diverse functions. These proteins are found in all domains of life and often perform essential roles in fundamental cellular processes. Analysis of data from genome sequencing projects demonstrates that bacteria possess a core of 11 universally conserved GTPases (elongation factor G and Tu, initiation factor 2, LepA, Era, Obg, ThdF/TrmE, Ffh, FtsY, EngA and YchF). Investigations aimed at understanding the function of GTPases indicate that a second conserved feature of these proteins is that they elicit their function through interaction with RNA and/or ribosomes. An emerging concept suggests that the 11 universal GTPases are either necessary for ribosome function or transmitting information from the ribosome to downstream targets for the purpose of generating specific cellular responses. Furthermore, it is suggested that progenitor GTPases were early regulators of RNA ...

Energy Technology Data Exchange (ETDEWEB)

The magnetic separation technology using sub-microsized ferromagnetic particle is indispensable in many areas of medical biosciences. For example, ferromagnetic particles (200-500 nm) are widely used for cell sorting in stem cell research with the use of cell surface-specific antigens. Nanosized ferromagnetic particles (10-20 nm) have been suggested as more suitable in drug delivery studies given their efficiency of tissue penetration, however, the magnetic separation method for them has not been established. One of the major reasons is that magnetic force acting on the object particles decreases drastically as a particle diameter becomes small. In this study, magnetic force acting on the targets was enhanced by the combination of superconducting magnet and the filter consisting of ferromagnetic particle. By doing so, we confirmed that Fe{sub 3}O{sub 4} of 20 nm in diameter was trapped in the magnetic filter under an external magnetic field of 0.5 T. Fe{sub 3}O{sub ...

CERN Document Server

Modified gravity theories may provide an alternative to dark energy to explain cosmic acceleration. We argue that the observational program developed to test dark energy needs to be augmented to capture new tests of gravity on astrophysical scales. Several distinct signatures of gravity theories exist outside the linear regime, especially owing to the screening mechanism that operates inside halos like the Milky Way to ensure that gravity tests in the solar system are satisfied. This opens up several decades in length scale and new classes of galaxies at low-redshift that can be exploited by surveys. While theoretical work on models of gravity is in the early stages, we can already identify new regimes which cosmological surveys could target to test gravity. These include: 1. A small scale component that focuses on the interior and vicinity of galaxy and cluster halos. 2. Spectroscopy of low redshift galaxies, especially galaxies smaller than ...

Energy Technology Data Exchange (ETDEWEB)

The feasibility of containing genetically engineered bacteria with enhanced dehalogenating properties for in situ bioremediation was investigated. (1) An agarose matrix microbead protocol and a detection system for contained microorganisms or DNA were developed. Multiplex Polymerase Chain Reaction (PCR) allowed tracking of a consortium of encapsulated organisms or several gene targets from a single species. Gene sequences encoding the enzymes responsible for initiating the biodegradation of toluene, octane, and 2,4-D were detected by multiplex PCR and nucleic acid probes from similar to 1-10 biodegradative cells/g soil. Improved DNA extraction methods resulted in PCR reactions detecting similar to 6 cells/g soil. (2) The pcpB gene (for the broad-spectrum detoxicant pentachlorophenol (PCP) hydroxylase) isolated from Flavobacterium sp. strain ATCC 39723 was used in attempts to develop an improved dehalogenating recombinant microorganism for ...

CERN Document Server

We present space-based photometry of the transiting exoplanetary system HD 209458 obtained with the MOST (Microvariablity and Oscillations of STars) satellite, spanning 14 days and covering 4 transits and 4 secondary eclipses. The HD 209458 photometry was obtained in MOST's lower-precision Direct Imaging mode, which is used for targets in the brightness range $6.5 < V < 13$. We describe the photometric reduction techniques for this mode of observing, in particular the corrections for stray Earthshine. We do not detect the secondary eclipse in the MOST data, to a limit in depth of 0.053 mmag (1 \\sigma). We set a 1 \\sigma upper limit on the planet-star flux ratio of 4.88 x 10^-5 corresponding to a geometric albedo upper limit in the MOST bandpass (400 to 700 nm) of 0.25. The corresponding numbers at the 3 \\sigma level are 1.34 x 10^-4 and 0.68 respectively. HD 209458b is half as bright as Jupiter in the MOST bandpass. This low geometric ...

International Nuclear Information System (INIS)

Methods: Systemic irradiation of neuroaxis is an essential part in the management of medulloblastoma, stPNET and intracranial germ cell tumors. The introduction of quality assurance programs in radiooncology assures a precise radiotherapy of target volumes and is a prerequisite to improve survival. Results: Hyperfractionated radiotherapy has the potential of increasing dose to tumor more safely without increasing the risk for late adverse effects. Pilot studies revealed excellent tumor control in medulloblastoma with acceptable acute toxicity and a long-term survival of up to 96%. In medulloblastoma stereotactic radiation techniques reveal an acceptable toxicity and promising results in tumor control in recurrent disease or as primary treatment. They are now part of future treatment protocols in case of persisting residual tumor. Radiotherapy alone in pure germinoma is continuously yielding high cure rates. In secreting germ cell tumors ...

International Nuclear Information System (INIS)

The cross sections for /sup 250/Fm, /sup 244-246/Cf, /sup 242-244/Cm, and /sup 242/Am/sup g/ produced by the /sup 12/C+ /sup 242/Pu and the /sup 16/O+ /sup 238/U reactions leading to the same compound nucleus of /sup 254/Fm have been measured by using radiochemical methods. The excitation functions show that the difference between the /sup 12/C+ /sup 242/Pu and the /sup 16/O+ /sup 238/U reactions can be attributed mainly to the Coulomb barriers. Our results were compared with others reported previously for /sup 22/Ne+ /sup 232/Th, /sup 12/C+ /sup 238/U, /sup 12/C+ /sup 240,241/Pu, /sup 13/C+ /sup 241/Pu, /sup 16/O+ /sup 233/U, and /sup 16/O+ /sup 242/Pu reaction systems, and support a mechanism involving transfer of #alpha#-particle clusters (C,Be,He) from projectile to target for the production of Cf and Cm isotopes.

Energy Technology Data Exchange (ETDEWEB)

For IGCC, the primary investment is too high due to the demand of high gasification efficiency. For PFBCC, the thermal efficiency is too low due to the relatively low turbine inlet temperature and the hot working medium of the gas turbine is not easy to clean. A new scheme is proposed for coal fired combined cycle to overcome the main drawbacks of IGCC and PFBCC. The research targets are developing a new cycle construction of coal fired combined cycle to raise the efficiency and reduce the primary investment. Actually, the new scheme is a synthesis of some existing proposals. It adopts partial gasification to reduce the primary investment of the gasification equipment. The un-gasified surplus solid is then fed to a pressurized fluidized bed boiler, but adopting Curtiss Wright type external combustion to lower the ash content in the working medium. The gas fuel from the partial gasifier is combusted in a top combustor to further increase the working medium ...

International Nuclear Information System (INIS)

Target materials for inertial fusion energy (IFE) power plant designs might be selected for a wide variety of reasons including wall absorption of driver energy, material opacity, cost and ease of fabrication. While each of these issues are of great importance, target materials should also be selected based upon their safety and environmental (S and E) characteristics. The present work focuses on the recycling, waste management and accident dose characteristics of potential target materials. If target materials are recycled so that the quantity is small, isotopic separation may be economically viable. Therefore, calculations have been completed for all stable isotopes for all elements from lithium to polonium. The results of these calculations are used to identify specific isotopes and elements that are most likely to be offensive as well as those most likely to be acceptable in terms of their S and E ...

International Nuclear Information System (INIS)

The modeling methods used to compute the neutron-induced activation of target and near-target materials in the NIF facility are presented. A detailed space and energy description of the neutron environment in the different materials is provided. A new capability has been developed to treat in a general way the activation of debris produced in an operational regime of yield and no-yield experiments. First calculations are addressed to analyze the activity of the debris into the target chamber. The contribution of the different components to activity, interior dose rates, and waste disposal rating (WDR) is determined. The importance of the activation coming from primary irradiation in the target, and from secondary irradiation in debris deposited onto the first wall is assessed. Finally, waste hazards of the activated debris when removed out of the chamber and stored are analyzed. (authors)