Signal and imaging sciences workshop proceedings
Energy Technology Data Exchange (ETDEWEB)
Papers are presented in the areas of: Medical Technologies; Non-Destructive Evaluation; Applications of Signal/Image Processing; Laser Guide Star and Adaptive Optics; Computational Electromagnetic, Acoustics and Optics; Micro-Impulse Radar Processing; Optical Applications; TANGO Space Shuttle.
1997-11-01
Observatory: Cluster FM5 (Rumba) - SPASE Resource Description
Feb 7, 2011 ... The potentials of the spherical sensor and nearby conductors are controlled ... Incoming data are continuously monitored by algorithms in the software ... together with FM8 (Tango) by a Soyuz-Fregat rocket from Baikonur. ...
Mechanistic fracture criteria for the failure of human cortical bone
Energy Technology Data Exchange (ETDEWEB)
A mechanistic understanding of fracture in human bone is critical to predicting fracture risk associated with age and disease. Despite extensive work, a mechanistic framework for describing how the underlying microstructure affects the failure mode in bone is lacking.
2002-12-13
The impact of available information on negotiation results
British Library Electronic Table of Contents (United Kingdom)
Negotiation is the most famous tool for reaching an agreement between parties. Usually, the different parties can be modeled as a buyer and a seller, who negotiate about the price of a given item. In most cases, the parties have incomplete information about one another, but they can invest money and efforts in order to acquire information about each other. This leads to the question of how much each party will be willing to invest on information about its opponent, prior to the negotiation process. In this paper, we consider the profitability of automated negotiators acquiring information on their opponents. In our model, a buyer and a seller negotiate on the price of a given item. Time is costly, and incomplete information exists about the reservation price of both parties. The reservatio...
2010-01-01
UK PubMed Central (United Kingdom)
BackgroundThe aim of this study is to examine how clinicians and patients negotiate clinical need and treatment decisions within a context of finite resources. Dental implant treatment...Full Text Available
metadata, images and captions. - The Gateway to Astronaut ...
... the Zaire is not an efficient transportation link because of many rapids and falls to negotiate between Kinshasa and the port city of Matadi. ...
STS067-703D-090 Kinshasa ... - Earth from Space - Image Information
... rivers of the world, the Zaire is not an efficient transportation link because of many rapids and falls to negotiate between Kinshasa and the port city of Matadi. ...
A unique mechanistic method has been developed at the NASA Glenn Research Center to
2008-01-01
DOUBLE-SHELL TANK (DST) HYDROXIDE DEPLETION MODEL FOR CARBON DIOXIDE ABSORPTION
International Nuclear Information System (INIS)
This document generates a supernatant hydroxide ion depletion model based on mechanistic principles. The carbon dioxide absorption mechanistic model is developed in this report. The report also benchmarks the model against historical tank supernatant hydroxide data and vapor space carbon dioxide data. A comparison of the newly generated mechanistic model with previously applied empirical hydroxide depletion equations is also performed.
2009-04-30
Negotiated settlements with a cost of service backstop: The consequences for depreciation
International Nuclear Information System (INIS)
The movement from traditional regulatory hearings to negotiated settlements represents both a departure from cost of service regulation and a relaxation of regulatory oversight. Under negotiation parties are able to renegotiate inclusions in their cost of service while simultaneously creating a profit margin for the regulated firm where none existed under the cost of service outcome of a traditional hearing. This paper constructs a model to illustrate the existence of positive gains to pipeline and shipper from the re-allocation of expenses through time in the regulated pipeline services market in Canada. Behaviour consistent with the model is observable in anecdotal and econometric evidence gathered from the library of the National Energy Board of Canada, responsible for pipeline toll regulation in Canada. Empirical investigation by into settlement procedures in the Florida electricity market reveals similar findings; however, this analysis ...
2011-03-01
Energy Technology Data Exchange (ETDEWEB)
The House Committee report describes the purpose, background, committee considerations and findings, and correspondence relating to H. Con. Res. 50, which is intended to encourage the president to pursue international negotiations relating to the ozone layer. The intent is to develop an international protocol and regulatory framework that will protect the stratosphere from the effects of chlorofluorocarbons. The report notes that some nations have already taken unilateral remedial steps, but argues the benefits of a negotiated agreement worldwide.
1987-01-01
British Library Electronic Table of Contents (United Kingdom)
The online communicative environment is expected to revolutionize political discourse as it expands to cover underrepresented groups and ideas. In this platform, marginalized groups such as indigenous communities from the developing world can articulate claims, strategically mobilize and participate in the forms of meaning-making that constitute them. However, there is skepticism on the actual value of online spaces in effecting agency in an internet-mediated environment. Using James Scott's notion of 'hidden transcripts' and Andrew Feenberg's 'democratic rationalization of technology', the paper explores strategic approaches and historical, social, and political conditions embedded in the construction, negotiation, and transformation of indigenous online activist media. In-depth interview...
2012-01-01
UK PubMed Central (United Kingdom)
Cytosine methylation in DNA is a major epigenetic signal, and plays a central role in propagating chromatin status during cell division. However the mechanistic links between DNA methylation...Full Text Available
2009-01-01
Synthesis of deuterated eicosanoids
Energy Technology Data Exchange (ETDEWEB)
Deuterated lipoxygenase and cyclooxygenase derivatives of eicosatetraenoic acid (arachidonic acid) and their metabolites are indispensable tools for organic trace analysis, biomedical studies, and mechanistic investigations on the corresponding endogenous (unlabelled) eicosanoids. Methods for the preparation of deuterated eicosanoids are reviewed.
1986-03-01
UK PubMed Central (United Kingdom)
Background. The Free Radical Theory of Aging mechanistically links oxidative stress to aging. Okinawa has among the world's longest-lived populations but oxidative stress in this...Full Text Available
2010-01-01
Non-agonistic familiarity decreases aggression in male Turkish hamsters, Mesocricetus brandti
UK PubMed Central (United Kingdom)
In laboratory studies, hamsters (Mesocricetus spp.) exhibit intense male-male aggression, thus making them an excellent model system for studies of the functional and mechanistic...Full Text Available
2009-02-01
UK PubMed Central (United Kingdom)
Cytoadherence or sequestration is essential for the pathogenesis of the most virulent human malaria species, Plasmodium falciparum (P. falciparum). Similar to leukocyte-endothelium...Full Text Available
Mechanistic insights from a quantitative analysis of pollen tube guidance
UK PubMed Central (United Kingdom)
BackgroundPlant biologists have long speculated about the mechanisms that guide pollen tubes to ovules. Although there is now evidence that ovules emit a diffusible attractant, little...Full Text Available
Mammalian life-span determinant p66shcA mediates obesity-induced insulin resistance
UK PubMed Central (United Kingdom)
Obesity and metabolic syndrome result from excess calorie intake and genetic predisposition and are mechanistically linked to type II diabetes and accelerated body aging; abnormal nutrient and insulin...Full Text Available
2010-07-27
Effect of orientation on the in vitro fracture toughness ofdentin: The role of toughening mechanisms
Energy Technology Data Exchange (ETDEWEB)
A micro-mechanistic understanding of bone fracture thatencompasses how cracks interact with the underlying microstructure anddefines their local failure mode is lacking, despite extensive research nthe response of bone to a variety of factors like aging, loading, and/ordisease.
2003-01-28
UK PubMed Central (United Kingdom)
A goal of our research is to identify biochemical factors that underlie the susceptibility of bone marrow cell populations to benzene metabolites so as to develop a mechanistically based chemoprotective...Full Text Available
1996-12-01
Negotiating equity for management of DOE wastes
Energy Technology Data Exchange (ETDEWEB)
One important factor frustrating optimal management of Department of Energy (DOE)-complex wastes is the inability to use licensed and permitted facilities systematically. Achieving the goal of optimal use of DOE`s waste management facilities is politically problematic for two reasons. First, no locale wants to bear a disproportionate burden from DOE wastes. Second, the burden imposed by additional wastes transported from one site to another is difficult to characterize. To develop a viable framework for equitably distributing these burdens while achieving efficient use of all DOE waste management facilities, several implementation and equity issues must be addressed and resolved. This paper discusses stakeholder and equity issues and proposes a framework for joint research and action that could facilitate equity negotiations among stakeholder and move toward a more optimal use of DOE`s waste management capabilities.
1994-09-01
British Library Electronic Table of Contents (United Kingdom)
This paper analyses the role of the translator in the representation of alterity and the construction of national identity, with reference to the work of a nineteenth-century Egyptian translator, essayist and educationalist, Rif?'a R?fi' al-TahT?wi (1801-1874). The essay takhliS al-ibriz fi talkhiS b?ris ("The Extraction of Gold in the Summarizing of Paris") includes numerous examples of constructive translation and representation, which familiarised and legitimised the "other" through the identification of parallels, common values and experience. Al-TahT?wi negotiated between conflicting discourses of modernism and traditionalism, and it is argued that the issues of representation raised in his work are of particular relevance to contemporary concerns in the ...
2007-01-01
British Library Electronic Table of Contents (United Kingdom)
The Seventh Meeting of the Conference of the Parties (2004) of the Convention on Biological Diversity established a mandate for the negotiation of an international regime on Access to Genetic Resources and Benefit Sharing arising from their utilization. Negotiations have been proceeding and have entered the final phase. Seven working group meetings have been held to date and there is expectation that an instrument will emerge by the final deadline - the Tenth Meeting of the Conference of the Parties in Nagoya, Japan in October 2010. A key component singled out for inclusion in the international regime relates to the recognition and protection of the rights of indigenous and local communities (ILCs) over their traditional knowledge (TK) associated with genetic resources. The Ninth Meeting o...
2010-01-01
Extended cognition and the space of social interaction
British Library Electronic Table of Contents (United Kingdom)
The extended mind thesis (EM) asserts that some cognitive processes are (partially) composed of actions consisting of the manipulation and exploitation of environmental structures. Might some processes at the root of social cognition have a similarly extended structure? In this paper, I argue that social cognition is fundamentally an interactive form of space management-the negotiation and management of "we-space"-and that some of the expressive actions involved in the negotiation and management of we-space (gesture, touch, facial and whole-body expressions) drive basic processes of interpersonal understanding and thus do genuine social-cognitive work. Social interaction is a kind of extended social cognition, driven and at least partially constituted by environmental (non-neural) scaffold...
2011-01-01
The Montreal protocol: A dynamic agreement for protecting the ozone layer
Energy Technology Data Exchange (ETDEWEB)
The Montreal Protocol provides the international community with an effective equitable and dynamic mechanism for protecting the ozone layer. The paper uses the Protocol's negotiating history to describe how and why agreement on a particular issue was reached and provides an in-depth analysis of the Protocol's most innovative provisions. The paper discusses international implementation of the Protocol. It concludes with a brief description of recent developments leading up to the Protocol's possible modification in June 1990. (14 refs.).
1990-04-01
Solar rises in the south; Le solaire se leve au sud
Energy Technology Data Exchange (ETDEWEB)
This autumn, Nice welcomed the thirteen European photovoltaic conference. It was the occasion for the world of solar energy to measure technical progress which were carried out and the market which are still to win. If developing countries are a reserve of new markets, they are not solvent and programmes depend on North/South negotiations. (N.C.).
1996-01-01
Management buyouts in the coal industry - are they a viable proposition?
Energy Technology Data Exchange (ETDEWEB)
Following the management buy out (MBO) at British Coal`s Hatfield Colliery, a member of the Solicitors involved looks at some of the issues to be considered in coal industry MBO`s. British Coal should be notified, a business plan will be needed for handling venture capital and other issues, and warranties need negotiating.
1994-09-01
Johnston vows to head off gas proration ban
International Nuclear Information System (INIS)
This paper reports that Sen. Bennett Johnston (D-La.) has vowed if Congress enacts an omnibus energy bill in the fall, it will not include a restriction on states' rights to proration natural gas production. Johnston, Senate energy committee chairman, will lead Senate conferees in their negotiations with members of the House of Representatives. The House energy bill has an antiproration amendment. The Senate's bill does not. Oklahoma's and Texas' recent actions to proration gas production prompted the federal legislation.
DOE supports market-based pricing in case before FERC
Energy Technology Data Exchange (ETDEWEB)
The Department of Energy has used its seldom-used statutory authority and filed comments with the Federal Energy Regulatory Commission urging support for Public Service Company of Indiana's request that the FERC allow it to sell up to 450 megawatts of firm power to eligible wholesale purchasers at negotiated or market-based rates in exchange for open transmission access for other generators.
1990-04-12
Critical concentrations in France; Les charges critiques en France
Energy Technology Data Exchange (ETDEWEB)
The critical concentrations correspond to contamination thresholds of environments over which noxious effects can occur and deteriorate soils, water and vegetation. They are defined according to the type of pollutants and their mode of action. The aim of this document is to provide a scientific framework to the policies of reduction of atmospheric pollution negotiated at Geneva`s convention. The methodology of evaluation, the results obtained for surface waters and forest soils, the perspectives of French research and the integration of French knowledge in the European database are presented. (J.S.)
1997-12-31
International Nuclear Information System (INIS)
The Cycle 8A static tests conducted in the Fast Flux Test Facility (FFTF) during 1986 have resulted in the separation of various feedback reactivity components. These feedback components, described by closed-form equations depending only on the reactor temperature field, can be regarded as database for the validation and/or calibration of feedback mechanistic models. The SASSYS safety analysis code contains the most developed feedback reactivity models and was selected for the comparison study between database and mechanistic calculations for the FFTF. Although detailed feedback models for control rod repositioning and core radial expansion/bowing exist, only the simple models were available in SASSYS at the time of this study. The results are described in this paper.
1988-05-01
This document concerns the proposal to negotiate an amendment to an existing contract for the supply of thick 6 inch silicon micro-strip sensors for the CMS tracker. For the reasons explained in this document, the Finance Committee is invited to approve an amendment to an existing contract with HAMAMATSU PHOTONICS (CH) for the supply of 7 000 thick 6 inch silicon micro-strip sensors for the CMS tracker, for an amount of 3 248 000 euros (5 131 840 Swiss francs), not subject to revision, with an option for up to 11 000 additional sensors, for a maximum amount of 4 708 000 euros (7 438 640 Swiss francs), not subject to revision, bringing the total maximum amount of the amendment to 7 956 000 euros (12 570 480 Swiss francs) not subject to revision. This total maximum amount will be added to the initial contract amount of 415 835 000 Japanese yen (4 879 824 Swiss francs), not subject to revision. The amounts in Swiss francs have been calculated using the present rate of ...
2004-01-01
On the problem of blast furnace coke quality
The introduction of large blast furnaces, oxygen-enriched blast and natural gas firing means that the coke rate is determined mainly by the ability of the coke charge to loosen up the burden and ensure a high level of permeability. Coke strength is now of great importance to the steelmaker, alongside ash and sulphur contents. The article suggests that moisture still offers a useful negotiating base for furnace operators and suppliers. It is important to know the moisture content and a sampling procedure is recommended for determining the moisture desorption time. Such tests also indicate any relationship between different quenching plants and the product.
1982-10-01
Energy Technology Data Exchange (ETDEWEB)
In the framework of the negotiations on the climatic changes, beginning at Rio in 1992, the France received an UN conference from the 4 to 15 of september 2000. This conference determined the necessary actions for the Kyoto protocol validation. This document presents in two part the program of these days. The first part is devoted to the world government policy and the second part defines the french actions decided to fight against the climatic change. A glossary of the main terms adapted to the climatic change domain, is also provided. (A.L.B.)
2000-07-01
Contract pricing of electric and telephone service: Current practice and policy
Energy Technology Data Exchange (ETDEWEB)
Due mainly to competitive pressures, the practice of offering electric and telephone service under contracts or special tariffs negotiated individually between a utility and its customers has increased in importance in recent years. Moreover, the practice is likely to become still more widespread in the future. This creates questions of public policy that are of interest to regulators and ratepayers alike such as how to supervise the practice, how to encourage utilities to compete while preventing cross-subsidization and anticompetitive behavior, and how the practice will ultimately affect utilities and ratepayers. This report sheds light on the topic by describing approaches that have been taken by the various regulatory commissions and by providing a framework for analyzing such contractors.
1992-04-01
Stabilization of Plutonium in Subsursface Environments via Microbial Reduction and Biofilm Formation
Energy Technology Data Exchange (ETDEWEB)
Our work is towards mechanistically understanding interactions of unsaturated bacterial biofilms and their extracellular polymeric substances (EPS) with actinide metals and metal surrogates under vadose zone conditions. Because metal contaminants in the vadose zone co-occur with organic pollutants, some of our work has included experiments with organic pollutants.
2005-06-01
Energy Technology Data Exchange (ETDEWEB)
The degradation of chlorinated solvents by reduction at the surface of zero-valent metals and bimetallic systems has emerged as an important approach to the in-situ remediation of ground water. Reduction by iron metal was studied in batch and column systems to develop a mechanistic understanding of the reaction chemistry and to determine the factors that affect dechlorination rate and long term performance in field applications.
1996-10-01
Critical review of analytical correlations for two-phase flow regime transitions
International Nuclear Information System (INIS)
Two sets of analytical correlations describing transitions between two-phase flow regimes are reviewed and discussed. One, the T-D set, is based on mechanistic models; the other, the Weisman set, on experimental correlations. The T-D set is preferred for horizontal flow, whereas the Weisman set seems preferrable for vertical flow. A computer code (FLOP) based on the T-D theory is described and applied to validate the theory.
1983-06-15
Autocrine regulation of T-cell activation by ATP release and P2X7 receptors
UK PubMed Central (United Kingdom)
T-cell activation requires the influx of extracellular calcium, although mechanistic details regarding such activation are not fully defined. Here, we show that P2X7 receptors play a key...Full Text Available
2009-06-01
A dynamic approach to selectivity in heterogeneous partial oxidation
Energy Technology Data Exchange (ETDEWEB)
Despite the rapid development of literature pertaining to fundamental (1-4) studies of oxidation catalysis, a general theory of heterogeneous selective oxidation catalysis explaining the selectivity behavior of different metal oxide systems has not yet been developed. Redox mechanisms have been widely invoked in the kinetic and mechanistic descriptions of selective oxidation reactions, suggesting a dynamic behavior of hydrocarbon and oxygen interactions with the catalyst surface. Nevertheless, most of the recent theoretical approaches of this subject matter (5-7) are essentially static in nature. Correlations are made with surface structure on the basis of crystallographic considerations with selectivity being related to the nature, number, bond-strength and nearness of oxygen atoms in the neighborhood of adsorption centers. The effect of the reaction medium on the configuration of the catalyst surface, and thus its influence on the reaction path, are generally not ...
1987-08-01
Upholding the Convention on the Rights of the Child: A Quandary in Cyberspace
Put in place to protect the rights of the child, the Convention on the Rights of the Child is a set of non-negotiable standards. A core principle underpinning the Convention is the child's right to participate fully in social arenas and to access sources of social support without excessive interference. Juxtaposing this is the right of the child to be shielded from harm, abuse and exploitation. Over the past several decades the Internet has emerged as a fast and easily accessible medium for people to connect and communicate. While the Internet provides children with a source of support through chat rooms, online communities and social networking sites, just as equally it can expose vulnerable children to predatory and deviant individuals exacerbating the potential for harm. Upholding the Convention in cyberspace is a challenge. The Internet is not owned or regulated by any governing body and accountability is difficult to enforce. This article discusses some of the ...
2010-04-01
Slimhole drilling for geothermal exploration
Energy Technology Data Exchange (ETDEWEB)
Sandia National Laboratories manages the US Department of Energy program for slimhole drilling. The principal objective of this program is to expand proven geothermal reserves through increased exploration, made possible by lower-cost slimhole drilling. For this to be a valid exploration method, however, it is necessary to demonstrate that slimholes yield enough data to evaluate a geothermal reservoir, and that is the focus of Sandia`s current research. Sandia negotiated an agreement with Far West Capital, which operates the Steamboat Hills geothermal field, to drill and test an exploratory slimhole on their lease. The principal objectives for the slimhole were development of slimhole testing methods, comparison of slimhole data with that from adjacent production-size wells, and definition of possible higher-temperature production zones lying deeper than the existing wells.
1994-07-01
Pathways for implementing REDD+. Experiences from carbon markets and communities
Energy Technology Data Exchange (ETDEWEB)
This issue of Carbon Market Perspectives on 'Pathways for implementing REDD+: Experience from carbon markets and communities' discusses the role of carbon markets in scaling up investments for REDD+ in developing countries. Nine articles authored by experienced negotiators on REDD+, carbon market actors, project developers and other leading experts share experiences and make suggestions on the key elements of a future international REDD+ regime: Architecture and underlying principles, measuring, reporting and verification (MRV), private-sector involvement, the rights of indigenous people and local communities, biodiversity conservation and environmental integrity. The articles are grouped under three main topics: the lessons of existing REDD+ projects; the future REDD+ regime and the role of carbon markets; and experiences and ideas about the involvement of indigenous people and local communities. (LN)
2011-07-01
Nuclear explosives for peaceful purposes
Energy Technology Data Exchange (ETDEWEB)
The US Plowshare program, designed to develop peaceful uses of nuclear explosives, was vigorous between 1957-73 and was of concern during US and USSR nuclear treaty negotiations within that period. In order to accommodate possible future applications, the Peaceful Nuclear Explosions Treaty was signed in 1976. The US program explored the phenomenology of nuclear explosions and tested their use in industrial applications. Due to waning industrial interest and public concern over environmental issues, the US program was terminated in 1977. The Soviet counterpart to the Plowshare program, which has involved more than 100 experiments throughout the USSR, continued until the self-imposed moratorium in 1985. As any peaceful use of nuclear explosives has the potential of furthering weapons research, the US takes the position that all such experiments would have to be banned in a comprehensive test ban treaty. 24 refs.
1986-11-01
Nuclear explosives for peaceful purposes
Energy Technology Data Exchange (ETDEWEB)
The US Plowshare programme, designed to develop peaceful uses of nuclear explosives, was vigorous between 1957 to 1973 and was of concern during US and USSR nuclear treaty negotiations within that period. In order to accommodate possible future applications, the Peaceful Nuclear Explosions (PNE) Treaty was signed in 1976. The US programme explored the phenomenology of nuclear explosions and tested their use in industrial applications. Due to waning industrial interest and public concern over environmental issues, the US program was terminated in 1977. The Soviet counterpart to the Plowshare programme, which has involved roughly 100 experiments throughout the USSR, continued until the self-imposed moratorium in 1985. As any peaceful use of nuclear explosives has the potential of furthering weapons research, the US takes the position that all such experiments would have to be banned in a comprehensive test ban treaty (CTBT).
1986-07-01
Energy Technology Data Exchange (ETDEWEB)
Man's wastes are polluting the oceans from various sources and delivered by various routes. The result has been the loss of habitat and the irreversible altering of marine ecosystems. Development in the coastal zones and offshore activities that disrupt biologically sensitive areas have led to international negotiations to regulate these impacts and develop a law of the sea. Basic to international cooperation, however, is the need to develop answers to questions about the ecological consequences of development programs and the carrying capacity of the oceans. Current information does not demonstrate long-term global impacts, making it difficult to detect and predict incremental changes and causal relationships. Society needs to determine how much environmental damage it will accept and then to develop appropriate technology, such as biomonitoring. Society also needs to reexamine its positions on technology-based regulatory controls to see if the effects of ...
1981-03-01
Hanford Environmental Information System (HEIS). Volume 2, Operator`s guide
Energy Technology Data Exchange (ETDEWEB)
This report discusses the procedures that establish the configuration control processes for the Hanford Environmental Information System (HEIS) software. The procedures also provide the charter and function of the HEIS Configuration Control Board (CCB) for maintaining software. The software configuration control items covered under these procedures include the HEIS software and database structure. The configuration control processes include both administrative and audit functions. The administrative role includes maintaining the overall change schedule, ensuring consistency of proposed changes, negotiating change plan adjustments, setting priorities, and tracking the status of changes. The configuration control process audits to ensure that changes are performed to applicable standards.
1994-01-14
British Library Electronic Table of Contents (United Kingdom)
The Kyoto Protocol attempts through political negotiations to guide participating industrialized countries' greenhouse gas (GHG) emissions from a positive growing trend, to reach a peak point (or turning point), and then be reduced to a negative growth. That means the relationship between decreasing GHG emissions and economic growth may be described by an inverted-U curve (or called a bell-shaped curve), which is consistent with the concept of the Environmental Kuznets Curve (EKC) hypothesis.This research observed that the economic development and GHG emissions in Economies in Transition (EITs) exhibit a hockey-stick curve trend (or called quasi-L-shape curve), that also generates a lot of "hot air" which is significant to the implementation of the Kyoto Protocol. In addition, through the ...
2008-01-01
British Library Electronic Table of Contents (United Kingdom)
Mathematics education reform emphasises the need to move away from transmission models of teaching to discursive classroom practices in which students negotiate and justify solutions to problems. This shift has potential, but not inevitable, implications for students' mathematical identities with respect to their sense of ownership and participation in mathematics as a creative activity, and is particularly pertinent in the UK context where ability grouping is prevalent. This paper presents an analysis of 13-15-year-old British pupils' accounts of learning and doing mathematics, and shows that the pedagogic practices of ability grouping do indeed play a major part in the development of participatory identities for some pupils but not for others. The data also show that learning is more tha...
2007-01-01
EMPLOYMENT, CAPITAL, AND PRODUCTIVITY DYNAMICS: EVIDENCE FROM THE MANUFACTURING SECTOR IN URUGUAY
British Library Electronic Table of Contents (United Kingdom)
Using a sample of Uruguayan manufacturing establishments we analyze employment, capital, and productivity dynamics over a period of currency appreciation; changes in trade policy; and changes in the institutional setting of wage negotiations. As the relative capital-labor price ratio fell, capital intensity increased. At the same time, there was an increase in labor and total factor productivity. Creation and destruction rates were relatively high and pervasive over time, sectors, establishment size, and establishment age, with exits explaining a sizeable part of destruction rates. Most of the excess reallocation was due to movements -within- rather than -between- sectors. Thus, high reallocation rates were linked to establishment-level heterogeneity rather than aggregate shocks.
2011-01-01
Toward a rule-based biome model
Energy Technology Data Exchange (ETDEWEB)
Current projections of the response of the biosphere to global climatic change indicate as much as 50% to 90% spatial displacement of extratropical biomes. The mechanism of spatial shift could be dominated by either (1) competitive displacement of northern biomes by southern biomes, or (2) drought-induced dieback of areas susceptible to change. The current suite of global biosphere models cannot distinguish between these two processes, thus determining the need for a mechanistically based biome model. The model is in an early stage of development and will require several enhancements, including explicit simulation of potential evapotranspiration, extension to boreal and tropical biomes, a shift from steady-state to transient dynamics, and validation on other continents.
1991-01-01
Topoisomerases of kinetoplastid parasites: why so fascinating?
British Library Electronic Table of Contents (United Kingdom)
Summary DNA topoisomerases are the key enzymes involved in carrying out high precision DNA transactions inside the cells. However, they are detrimental to the cell when a wide variety of topoisomerase-targeted drugs generate cytotoxic lesions by trapping the enzymes in covalent complexes on the DNA. The discovery of unusual heterodimeric topoisomerase I in kinetoplastid family added a new twist in topoisomerase research related to evolution, functional conservation and their preferential sensitivity to Camptothecin. On the other hand, structural and mechanistic studies on kinetoplastid topoisomerase II delineate some distinguishing features that differentiate the parasitic enzyme from its prokaryotic and eukaryotic counterparts. This review summarizes the recent advances in research in kin...
2006-01-01
Energy Technology Data Exchange (ETDEWEB)
Research activity during the 1991--1992 funding period has been concerned with the following topics relevant to carbon monoxide activation. (1) Exploratory studies of water gas shift catalysts heterogenized on polystyrene based polymers. (2) Mechanistic investigation of the nucleophilic activation of CO in metal carbonyl clusters. (3) Application of fast reaction techniques to prepare and to investigate reactive organometallic intermediates relevant to the activation of hydrocarbons toward carbonylation and to the formation of carbon-carbon bonds via the migratory insertion of CO into metal alkyl bonds.
1992-06-04
Studies relevant to the catalytic activation of carbon monoxide
Energy Technology Data Exchange (ETDEWEB)
Research activity during the 1991--1992 funding period has been concerned with the following topics relevant to carbon monoxide activation. (1) Exploratory studies of water gas shift catalysts heterogenized on polystyrene based polymers. (2) Mechanistic investigation of the nucleophilic activation of CO in metal carbonyl clusters. (3) Application of fast reaction techniques to prepare and to investigate reactive organometallic intermediates relevant to the activation of hydrocarbons toward carbonylation and to the formation of carbon-carbon bonds via the migratory insertion of CO into metal alkyl bonds.
1992-06-04
International Nuclear Information System (INIS)
The mechanistic aspects of electrochemical reductions of U"V"IO_2(acac)_2dmso(acac=acetylacetonate, dmso=dimethyl sulfoxide) complex with bidentate ligand(acac) in DMSO were investigated by using cyclic voltammetry, normal pulse voltammetry, and spectrophotometer equipped with an optical transparent thin layer electrode cell. It is concluded that the uranyl complexes with bidentate ligands at the equatorial plane form stable U(V) complexes by the electrochemical reduction and that their molar extinction coefficients in the visible region are very small. (J.P.N.).
1996-01-01
Decontamination factors and release rates of UO/sub 2/ particles from boiling pools of sodium
Energy Technology Data Exchange (ETDEWEB)
A semi-mechanistic model for calculating solid radionuclide release rates from bubbling pools of sodium was developed. The influence of particle spacial and size distributions on the decontamination of the releases was analysed and found significant. Decontamination factors are shown as a function of pool depth, bubbling characteristics and particle size distribution. The calculation of a decontamination factor for estimating the source term of large scale hypothetical core disruptive accidents is presented. The decontamination factor for a large scale accident was found to be two orders of magnitude greater than results obtained from small scale experiments conducted with uniform particle distributions.
1983-01-01
Decontamination factors and release rates of UO"2 particles from boiling pools of sodium
International Nuclear Information System (INIS)
A semi-mechanistic model for calculating solid radionuclide release rates from bubbling pools of sodium was developed. The influence of particle spacial and size distributions on the decontamination of the releases was analysed and found significant. Decontamination factors are shown as a function of pool depth, bubbling characteristics and particle size distribution. The calculation of a decontamination factor for estimating the source term of large scale hypothetical core disruptive accidents is presented. The decontamination factor for a large scale accident was found to be two orders of magnitude greater than results obtained from small scale experiments conducted with uniform particle distributions. (orig.).
An overview of FFTF [Fast Flux Test Facility] contributions to Liquid Metal Reactor Safety
International Nuclear Information System (INIS)
The Fast Flux Test Facility has provided a very useful framework for testing the advances in Liquid Metal Reactor Safety Technology. During the licensing phase, the switch from a nonmechanistic bounding technique to the mechanistic approach was developed and implemented. During the operational phase, the consideration of new tests and core configurations led to use of the anticipated-transients-without-scram approach for beyond design basis events and the move towards passive safety. The future role of the Fast Flux Test Facility may involve additional passive safety and waste transmutation tests. 26 refs.
1990-11-11
START: An essential step in a new era
Energy Technology Data Exchange (ETDEWEB)
After more than nine years of negotiations, the US and the Soviet Union signed the Strategic Arms Reduction Treaty (START) in Moscow on July 31, 1991. While the world has changed dramatically since 1982 when the START negotiations began, the treaty remains very much in the US interest. START exacts deep cuts in the most destabilizing and dangerous US and Soviet strategic weapons, and will lead to substantial overall reductions in the strategic nuclear forces of both sides. Moreover, the agreement will create a formal, structured, and predictable strategic environment. It will also impose on the Soviet Union or its successors a legally binding set of obligations that will be in effect for many years, regardless of changes in leadership or form of government. START, with its extensive series of intrusive, cooperative, and technical verification measures, will greatly enhance US knowledge about Soviet strategic nuclear forces and activities. The ...
1991-11-01
Energy in Asia. An Outline of Some Strategic Energy Issues in Asia
Energy Technology Data Exchange (ETDEWEB)
The Asian countries are expected to generate 45% of the world energy consumption and Japan is the absolutely greatest consumer in Asia, but China is the country that will be most important as a new consumer on the world energy markets. China, like India and later possibly even Japan try to change to natural gas as a source of energy as much as possible. This is causing a competition about the resources that can be reached by pipelines for gas, which in practice means those in Russia and Central Asia. Russia is trying to control the gas in Central Asia. The competition is also increasing about oil. China is becoming heavily dependent on Muslim countries in the Middle East and Central Asia. This also leads to an effort to increase the safety along the sea lanes, which may collide with the interests of other countries. Territorial conflicts with gas and oil as underlying elements exist in Asia. USA is a player on the energy market, who is using military means as well, but it is possible ...
2003-01-01
Energy Technology Data Exchange (ETDEWEB)
A flowing bed kiln is a gas-solid reactor used in the civil nuclear fuel cycle for the successive conversion of uranium trioxide (UO{sub 3}) into uranium dioxide (UO{sub 2}) and then into uranium tetrafluoride (UF{sub 4}). A numerical model is developed which simulate the behaviour of this reactor in permanent regime. This model describes the physico-chemical phenomena involved, and combines a mechanistic approach in the vertical area of the kiln (resolution by the finite volumes method) and a systemic approach in the horizontal area, like in the model of cascade mixers. The first results have been obtained for reference operating conditions of the industrial kiln. Some possible improvements of the optimum temperature progression inside the kiln are evoked. (J.S.)
2001-07-01
SEPT9_i1 and genomic instability: Mechanistic insights and relevance to tumorigenesis
British Library Electronic Table of Contents (United Kingdom)
Abstract Septins are highly conserved cytoskeletal GTP-binding proteins implicated in numerous cellular processes from apoptosis to vesicle trafficking. Septins have been associated with leukemia and solid tumor malignancies, including breast, ovarian, and prostate. We previously reported that high SEPT9_i1 expression in human mammary epithelial cell lines (HMECs) led to malignant cellular phenotypes such as increased cell proliferation, invasiveness, motility, and genomic instability. Our goal here was to better understand how SEPT9_i1 expression might contribute to genomic instability and malignant progression. First, we confirmed that even transient expression of SEPT9_i1 was sufficient to increase aneuploidy in HMECs. We then analyzed SEPT9_i1 by immunoprecipitation and immunofluoresce...
2011-01-01
Roles of biomarkers in evaluating interactions among mixtures of lead, cadmium and arsenic
British Library Electronic Table of Contents (United Kingdom)
Human exposure to environmental chemicals is most correctly characterized as exposure to mixtures of these agents. The metals/metalloids, lead (Pb), cadmium (Cd), and arsenic (As), are among the leading toxic agents detected in the environment. Exposure to these elements, particularly at chronic low dose levels, is still a major public health concern. Concurrent exposure to Pb, Cd, or As may produce additive or synergistic interactions or even new effects that are not seen in single component exposures. Evaluating these interactions on a mechanistic basis is essential for risk assessment and management of metal/metalloid mixtures. This paper will review a number of individual studies that addressed interactions of these metals/metalloids in both experimental and human exposure studies with...
2008-01-01
British Library Electronic Table of Contents (United Kingdom)
Mechanistic studies on a charged ultrafiltration (UF) membrane fouled with natural organic matter (NOM) and colloidal particles are systematically investigated to understand the relative role of each NOM fraction and the presence of colloidal particulate to membrane fouling. Humic acid (HA), dextran, and kaolin were employed as surrogate model foulants representing the organic hydrophobic acid NOM, hydrophilic neutral NOM, and inorganic colloidal materials, respectively. The results obtained showed that the organic NOM of hydrophilic surrogate (dextran) plays a primary role in promoting membrane fouling, followed by hydrophobic acids and inorganic kaolin, but to a lesser extent than organic NOM compounds. Significant differences in the extent of fouling between dextran and HA have been obs...
2011-01-01
Recent developments in the CONTAIN-LMR code
International Nuclear Information System (INIS)
Through an international collaborative effort, a special version of the CONTAIN code is being developed for integrated mechanistic analysis of the conditions in liquid metal reactor (LMR) containments during severe accidents. The capabilities of the most recent code version, CONTAIN LMR/1B-Mod.1, are discussed. These include new models for the treatment of two condensables, sodium condensation on aerosols, chemical reactions, hygroscopic aerosols, and concrete outgassing. This code version also incorporates all of the previously released LMR model enhancements. The results of an integral demonstration calculation of a sever core-melt accident scenario are given to illustrate the features of this code version. 11 refs., 7 figs., 1 tab.
1990-08-12
Energy Technology Data Exchange (ETDEWEB)
The biological effects of ionizing radiation exposure are the result of a complex sequence of physical, chemical, biochemical, and physiological interactions. One way to begin a search for an understanding of health effects of radiation is through the development of phenomenological models of the response. Many models have been presented and tested in the slowly evolving process of characterizing cellular response. A range of models covering different endpoints and phenomena has developed in parallel. Many of these models employ similar assumptions about some underlying processes while differing about the nature of others. An attempt is made to organize many of the models into groups with similar features and to compare the consequences of those features with the actual experimental observations. It is assumed that by showing that some assumptions are inconsistent with experimental observations, the job of devising and testing mechanistic models can be simplified. ...
1990-09-01
British Library Electronic Table of Contents (United Kingdom)
Carbon black is widely used as an active filler in the rubber industry to improve the physical properties of rubber. The surface energy of carbon black is high compared to that of various elastomers like styrene?butadiene rubber (SBR), butadiene rubber (BR) and ethylene?propylene?diene rubber (EPDM). The work aims at reducing the surface energy of carbon black by modifying its surface for application especially in rubber blends. The present paper looks into the possibility of using plasma polymerisation of acetylene as a surface modification technique for carbon black in comparison with silica. Thermogravimetric analysis, wetting behaviour with various liquids of known surface tension and time of flight secondary ion mass spectrometry (ToF-SIMS) were used to characterise the carbon black b...
2008-01-01
Lower order roots more palatable to herbivores: a case study with two temperate tree species
British Library Electronic Table of Contents (United Kingdom)
Determining which kinds of roots are likely to be consumed by root herbivores may improve our understanding of the mechanistic control on fine root dynamics. Here, we tested the hypothesis that root herbivores prefer to consume the distal lower order roots in their branching networks. Insecticide was applied to soil to quantify effects of root herbivores on root biomass and production in the first five orders (the distal roots numbered as first-order) in Fraxinus mandshurica and Larix gmelinii plantations from May 2008 to July 2009. Root morphology, chemistry, anatomy and physiology were measured simultaneously across branching orders. Among the first five order roots, significant consumptions by herbivores were found only for the two distal lower order roots throughout growing seasons, wi...
2011-01-01
British Library Electronic Table of Contents (United Kingdom)
Considering the status of knowledge on corrosion and corrosion protection and especially the need for long term compatibility data of structural materials in HLM a set of experiments to generate reliable long term data was defined and performed. The long term corrosion behaviour of the two structural materials foreseen in ADS, 316L and T91, was investigated in the design relevant temperature field, i.e. from 300 to 550degreeC. The operational window of the two steels in this temperature range was identified and all oxidation data were used to develop and validate the models of oxide scale growth in PbBi. A mechanistic model capable to predict the oxidation rate applying some experimentally fitted parameters has been developed. This model assumes parabolic oxidation and might be used for de...
2011-01-01
Interfacial area transport: data and models
International Nuclear Information System (INIS)
The objective of this research is to replace the current flow regime dependent interfacial area correlations in the thermal-hydraulic system analysis codes with an interfacial area transport equation, which dynamically models two-phase flow regime transitions. The interfacial area transport equation applicable to bubbly flows has been developed based on mechanistic modeling of bubble interaction. Detailed experiments have been performed for bubbly conditions in 2.54, 5.08 and 10.16-cm ID pipes to benchmark the model. This new approach predicts the continuous changes of the interfacial area and will eliminate artificial bifurcations stemming from the use of the static flow regime transition criteria. This paper presents the preliminary results of incorporating the one-group transport equation into the USNRC consolidated code, currently under development. The framework for the two-group transport equation and the necessary constitutive relations are also presented. ...
2001-05-23
Homogeneous models for mechanisms of surface reactions: Propylene ammoxidation
Energy Technology Data Exchange (ETDEWEB)
The proposed active sites on the catalyst surface in heterogeneous propylene ammoxidation have been successfully modelled by structurally characterized pinacolato W(VI) tert-butylimido complexes. These compounds exist as an equilibrating mixture of amine-bis(imido) and imido-bis(amido) complexes, the position of this equilibrium is dependent on the electronic nature of the glycolate ligand. Both of the C-N bond-forming reactions proposed in recent studies by Grasselli et al. (1) have been reproduced using discrete Group VI d{sup 0} organoimido complexes under mild conditions suitable for detailed mechanistic studies. These reactions are: (1) oxidative trapping of radicals at molybdenum imido sites, and (2) migration of the allyl group from oxygen to an imido nitrogen atom.
1987-04-01
Free-electron-laser-induced shock-wave control and mechanistic analysis using pulse control
International Nuclear Information System (INIS)
The wavelength of the free electron laser (FEL) in Osaka University can be continuously varied in the range of 5.0-20.0 #mu#m. The FEL has a double-pulse structure, consisting of a train of macropulses of pulse duration 12 #mu#s. Each macropulse contains a train of 330 micropulses of pulse duration 5 ps. The tunability and picosecond pulses afford new medical and biological applications. However, a macropulse of long pulse duration leads to undesirable secondary effects. Precise control of the macropulse duration is essential for the high-precision applications of the FEL. An FEL pulse control system using acousto-optic modulators has been developed to investigate mechanical (shock-wave) effects of the FEL on living tissues. With this system, we have controlled photoinduced shock waves and determine the mechanism of interaction during FEL-induced tissue ablation.
2008-11-01
Fe-Se-tellurates as ammoxidation catalysts
Energy Technology Data Exchange (ETDEWEB)
Acrylonitrile is a versatile intermediate and is produced by the Sohio ammoxidation process world-wide at a level of 8 billion pounds per year. In the catalytic process, propylene, ammonia and air are converted to acrylonitrile directly. The most widely used catalysts are mixed metal molybdates or antimonates. The current investigation deals with metal tellurates as possible low temperature ammoxidation catalysts. Of the catalysts investigated, iron-selenium-tellurates are of particular interest since they exhibit good ammoxidation activity already at 320/sup 0/C which is about 100/sup 0/C lower than the temperature required for molybdate or antimonate systems. Mechanistically, the tellurates behave more similarly to the antimonates than the molybdates. 3 tabs., 4 figs., 13 refs.
1986-08-15
Effects of C-60 fullerenes and carbon nanotubes on marine mussels.
Environmental Research Database
Objectives1. We will use reduction of lysosomal stability as an indicator of cell injury induced by C-60 fullerenes and carbon nanotubes in the liver analogue or digestive gland (hepatopancreas) of marine mussels. Molluscan hepatopancreatic digestive cells are key to normal function and are a sensitive key interface with the environment. Reduction of lysosomal stability is mechanistically linked with impaired health of the whole animal. 2. We will also test the hepatopancreatic digestive cells for evide [continued...]DescriptionNanotechnology is a major innovative scientific and economic growth area, which may present a variety of hazards for environmental and human health. The surface properties and very small size of nanoparticles and nanotubes provides surfaces that may bind and transport toxic chemical pollutants, as well as possibly being toxic in their own right by generating reactive oxygen species (ROS). There is a wealth of evidence for the harmful effects ...
2008-01-25
Disruptive core relocation analysis of PHEBUS/FPT0 test with SAMPSON code
International Nuclear Information System (INIS)
SAMPSON is an integration of twelve analysis modules under the final development phase (phase-2) and will be capable of simulating hypothesized severe accidents in a nuclear power plant. One of these modules, the Molten Core Relocation Analysis (MCRA) module, simulates the relocation behavior of a molten core during a severe accident. MCRA models severe accident phenomena by using mechanistic formulations for multi-phase, multi-component, and multi-velocity field. As one of the verification studies of SAMPSON in Phase-1, the in-core phenomena of PHEBUS/FPT0 was analyzed with three modules, MCRA, fuel rod heat up analysis (FRHA) module, and the analysis control module (ACM) of SAMPSON. (author)
2000-10-01
Differential immunotoxic effects of inorganic and organic mercury species in vitro
British Library Electronic Table of Contents (United Kingdom)
Despite the fact that humans are exposed to multiple forms of mercury (elemental, inorganic, and organic), most research on mercury toxicity has focused on methylmercury (MeHg) and on neurotoxic outcomes and mechanisms. Recent work has indicated that the immunotoxic effects of mercury compounds may be significant contributors to human disease as well as mechanistically relevant to other target organ toxicities. In this study, we compared the effects of inorganic Hg (iHg) to organic Hg species (MeHg and ethylmercury, EtHg) in human peripheral blood mononuclear cells (PBMCs) in vitro at sub-cytotoxic concentrations, using methods developed to characterize response of human PBMCs to iHg in vitro. PBMCs were isolated from six volunteer blood donors (three males and three females) and cultured ...
2010-01-01
British Library Electronic Table of Contents (United Kingdom)
A model is developed to represent mechanical strain, stress-enhanced dissolution, and shear dilation as innately hysteretic and interlinked processes in rough contacting fractures. The model is incorporated into a numerical simulator designed to examine permeability change and thermal exchange in chemically active and deformable fractured reservoirs. A candidate engineered geothermal reservoir system (EGS) is targeted. The mechanistic model is able to distinguish differences between the evolution of fluid transmission characteristics of (1) small scale, closely spaced fractures, and (2) large-scale, more widely spaced fractures. Alternate realizations of fracture frequency and scale, exhibiting identical initial bulk permeability, lead to significantly different conclusions regarding perme...
2010-01-01
Asymmetric Hydrogenation with Highly Active IndolPhos-Rh Catalysts: Kinetics and Reaction Mechanism
British Library Electronic Table of Contents (United Kingdom)
The mechanism of the IndolPhos-Rh-catalyzed asymmetric hydrogenation of prochiral olefins has been investigated by means of X-ray crystal structure determination, kinetic measurements, high-pressure NMR spectroscopy, and DFT calculations. The mechanistic study indicates that the reaction follows an unsaturate/dihydride mechanism according to Michaelis-Menten kinetics. A large value of KM (KM=5.01+-0.16 M) is obtained, which indicates that the Rh-solvate complex is the catalyst resting state, which has been observed by high-pressure NMR spectroscopy. DFT calculations on the substrate-catalyst complexes, which are undetectable by experimental means, suggest that the major substrate-catalyst complex leads to the product. Such a mechanism is in accordance with previous studies on the mechanism...
2010-01-01
Aromatics oxidation and soot formation in flames. Progress report, August 15, 1993--June 30, 1994
Energy Technology Data Exchange (ETDEWEB)
This project is concerned with the kinetics and mechanisms of aromatic oxidation and soot and fullerenes formation in flames. The objective of the aromatics oxidation work is to identify and measure the concentration of important intermediates and products in benzene oxidation, and to determine reaction mechanisms and kinetics properties consistent with the behavior seen in flames. The research on soot formation is concerned primarily with the particle inception stages, but the work includes study of soot structure at all stages of growth in order to obtain mechanistic information from evidence of growth steps recorded in the structure of the particles. The ultimate objective is to understand how nascent soot particles are formed from high molecular weight compounds, including the roles of planar and curved PAH and the relationship between soot and fullerenes. The objective of the proposed research on fullerenes is to develop a more comprehensive understanding of ...
1994-10-01
Analysis of heterogeneous cell populations: A density-based modeling and identification framework
British Library Electronic Table of Contents (United Kingdom)
Abstract: In many biological processes heterogeneity within clonal cell populations is an important issue. One of the most striking examples is a population of cancer cells in which after a common, identical death signal some cells die whereas others survive. The reason for this heterogeneity is intrinsic and extrinsic noise. In this paper we present a mechanistic multi-scale modeling framework for cell populations, in which the dynamics of every individual cell is captured by a parameter dependent stochastic differential equation (SDE). Heterogeneity among individual cells is accounted for by differences in parameter values, modeling extrinsic influences. Based on the statistical properties of the extrinsic noise and the SDE model for the individual cell, a partial differential equation (...
2011-01-01
Advanced Monitoring and Control of Multi monomer System in Emulsion Polymerization
British Library Electronic Table of Contents (United Kingdom)
Abstract A control framework was developed for real time implementation of optimal control of emulsion polymerization with multiple monomers by integrating model based algorithms with software engines. The developed system was applied for controlling conversion, particle size, molar mass, and polymer composition using model predictive control (MPC) based on mechanistic models for emulsion polymerization. The control formulation was extended to account for existing process constraints on the input, input moves, and solids content. On experimental testing, the developed control scheme was found to achieve the desired objectives without violating the process constraints and showed good robustness in rejecting disturbances. Improvements in the process operation and polymer property control wer...
2010-01-01
A strategy of implementation of the improved constitutive equations for the advanced subchannel code
International Nuclear Information System (INIS)
To develop the advanced subchannel analysis code, the dominant factors that influence the boiling transitional process must be taken into account in the mechanistic constitutive equations based on the flow geometries and the fluid properties. The dominant factors that influence the boiling transitional processes are (1) the gas-liquid re-distribution by cross flow, (2) the liquid film dryout, (3) the two-phase flow regime transition, (4) the droplet deposition, and (5) the spacer-droplet interaction. At first, we indicated the strategy for the development of the constitutive equations for the five dominant factors based on the experimental database by the latest measurement technique and the latest computational fluid dynamics method. Then, the problems of the present constitutive equations and the improvement plan of the constitutive equations were indicated. Finally, the layered structure for the two-phase/three-field subchannel code including the new ...
2004-10-04
British Library Electronic Table of Contents (United Kingdom)
Abstract One of the most significant problems in industrial bioprocessing of recombinant proteins using engineered mammalian cells is the phenomenon of cell line instability, where a production cell line suffers a loss of specific productivity (qP). This phenomenon occurs with unpredictable kinetics and has been widely observed in Chinese hamster ovary (CHO) cell lines and with all commonly used gene expression systems. The underlying causes (both genetic and physiological) and the precise molecular mechanisms underpinning cell line instability have yet to be fully elucidated, although recombinant gene silencing and loss of recombinant gene copies have been shown to cause qP loss. In this work we have investigated the molecular mechanisms underpinning qP instability over long-term sub-cult...
2011-01-01
3D model for a secondary facultative pond
British Library Electronic Table of Contents (United Kingdom)
This paper describes a comprehensive model of wastewater treatment in secondary facultative ponds, which combines 3D hydrodynamics with a mechanistic water quality model. The hydrodynamics are based on the Navier-Stokes equation for incompressible fluids under shallow water and Boussinesq assumptions capturing the flow dynamics along length, breadth and depth of the pond. The water quality sub model is based on the Activated Sludge Model (ASM) concept, describing COD and nutrient removal as function of bacterial growth following Monod kinetics, except for Escherichia coli removal, which was modelled as first order decay. The model was implemented in the Delft3D software and was used to evaluate the effect of wind and the addition of baffles on the water flow pattern, temperature profiles i...
2011-01-01
Usefulness of multifunctional gastrointestinal coil catheter for colorectal stent placement
Energy Technology Data Exchange (ETDEWEB)
The purpose of this study was to evaluate the usefulness of a multifunctional gastrointestinal coil catheter for stent placement in 98 patients with colorectal strictures. The catheter was used in 98 consecutive patients for stent placement in the rectum (n = 24), recto-sigmoid (n = 13), sigmoid (n = 38), descending (n = 6), transverse (n = 11), splenic flexure (n = 3), hepatic flexure (n = 2), and ascending (n = 1) colon. The catheter was made of a stainless steel coil (1.3 mm in inner diameter), a 0.4-mm nitinol wire, a polyolefin tube, and a hemostasis valve. Usefulness of the catheter was evaluated depending on whether the catheter could pass a stricture over a guide wire and whether measurement of the stricture length was possible. The passage of the catheter over a guide wire beyond the stricture was technically successful and well tolerated in 93 (94.9%) of 98 patients. In the failed five patients, it was not possible to negotiate the guide wire due to ...
2008-11-15
DEFF Research Database (Denmark)
There is increasing evidence that chemicals/test substances cannot only have adverse effects, but that there are many substances that can (also) have a beneficial effect on health. As this journal regularly publishes papers in this area and has every intention in continuing to do so in the near future, it has become essential that studies reported in this journal reflect an adequate level of scientific scrutiny. Therefore a set of essential characteristics of studies has been defined. These basic requirements are default properties rather than non-negotiables: deviations are possible and useful, provided they can be justified on scientific grounds. The 10 basic requirements for a scientific paper reporting antioxidant, antimutagenic or anticarcinogenic potential of test substances in in vitro experiments and animal studies in vivo concern the following areas: (1) Hypothesis-driven study design; (2) The nature of the test substance; (3) Valid and invalid test ...
2003-01-01
Energy Technology Data Exchange (ETDEWEB)
Section 7 of the Atomic Energy Act (AtG), section 4 of the Federal Emission Control Act (BImSchG), the Nuclear Installations Licensing Ordinance (AtVfV), and the Ninth Ordinance on the Implementation of the BImSchG (Principles of the licensing procedure) require participation of the public in the procedure before administrative provisions or decisions are issued. The book presents the legally prescribed steps at which participation of the public is mandatory, for the simple case (only one license on the agenda), and for the multi-stage licensing procedure: preliminary negotiations / filling of applications for a license and filing of documents / public announcement of projects / access to files / objections / preclusion of delayed objections / public hearing and other expert discussions / termination of procedure, decision-making by the authorities / decisions on subdivision of procedure into defined stages / modification of the procedure. The analysis of the ...
1994-01-01
Estimating and managing uncertainties in order to detect terrestrial greenhouse gas removals
Energy Technology Data Exchange (ETDEWEB)
Inventories of emissions and removals of greenhouse gases will be used under the United Nations Framework Convention on Climate Change and the Kyoto Protocol to demonstrate compliance with obligations. During the negotiation process of the Kyoto Protocol it has been a concern that uptake of carbon in forest sinks can be difficult to verify. The reason for large uncertainties are high temporal and spatial variability and lack of representative estimation parameters. Additional uncertainties will be a consequence of definitions made in the Kyoto Protocol reporting. In the Nordic countries the national forest inventories will be very useful to estimate changes in carbon stocks. The main uncertainty lies in the conversion from changes in tradable timber to changes in total carbon biomass. The uncertainties in the emissions of the non-CO{sub 2} carbon from forest soils are particularly high. On the other hand the removals reported under the Kyoto Protocol will only be a ...
2002-07-01
International Nuclear Information System (INIS)
The French nuclear power program was pushed through in order to reduce the country's dependence on imported fossil sources of energy. Nuclear power and hydro power have achieved a level of self-sufficiency in the energy sector of more than 50%. It should be emphasized that the French nuclear power program was largely self-financed. Electricite de France (EdF) considers itself well prepared for the European market, provided the creation of the single market implies that electricity rates are taken as a yardstick of competitiveness. Negotiations about a European directive on deregulating the electricity market were for the government to hold. EdF pleaded in favor of preserving for each country a certain leeway for shaping its own policy. The road to deregulation was to be opened, but the specific situation of each country was to be taken electricity to be passed through imposes narrow constraints upon an expansion of exchanges of electricity, and public acceptance is ...
1996-01-01
Climate - air traffic emissions
Energy Technology Data Exchange (ETDEWEB)
In 1990, 176 million tonnes (mt) of air-traffic fuel was burned, which produced about 550 mt CO{sub 2}, 220 mt water, 3.5 mt NO{sub x} amd 0.18 mt SO{sub 2}. NO{sub x} emissions from air traffic may, by increasing ozone concentrations, be responsible for about 8% of global greenhouse warming. In the stratosphere NO{sub x} from aircraft is partly responsible for ozone depletion. With present technology 500 aircraft in the stratosphere would cause global ozone losses of 20%. Water vapour added by aircraft also contributes to global warming. In the form of ice crystals between 8 to 13 km above sea level, it acts as cirrus clouds. Probably the least damaging cruising altitude for aircraft is 9 km above sea level. Fuel consumption by aircraft is increasing. Air pollution abatement measures include substituting hydrogen fuel for kerosene, developing engines that emit less NO{sub x} and the introduction of internationally negotiated taxes on kerosene. 30 refs.
1991-11-01
Energy Technology Data Exchange (ETDEWEB)
Lawrence Livermore National Laboratories` Zephyr System provides a showcase for the ways in which emerging technologies can help streamline procurement processes and improve the coordination between participants in engineering projects by allowing collaboration in ways that have not been possible before. The project also shows the success of a highly pragmatic approach that was initiated by the end user community, and that intentionally covered standard situations, rather than aiming at also automating the exceptions. By helping push purchasing responsibilities down to the end user, thereby greatly reducing the involvement of the purchasing department in operational activities, it was possible to streamline the process significantly resulting in time savings of up to 90%, major cost reductions, and improved quality. Left with less day-to- day purchasing operations, the purchasing department has more time for strategic tasks such as selecting and pre-qualifying new suppliers, ...
1998-04-01
Application of quality improvement techniques to meet coke battery environmental regulations
Citizens Gas and Coke Utility operates three coke oven batteries, producing both foundry coke and blast furnace coke, under the trade name Indianapolis Coke. Active participation in the regulation negotiation process by the Vice President of Indianapolis Coke allowed the company to accurately anticipate the environmental regulations, long before they were set in law. Several improvements were put into motion that helps them meet the new environmental regulations. Better trained operators with new job positions dedicated solely to environmental compliance, an extensive environmental training program, and two innovations, a portable oven door milling and cleaning machine and three new computer applications are the result of team efforts. The focus of this paper is development of the computer applications designed to enhance three areas of environmental compliance. The three areas addressed by the applications are documentation and information deployment, problem ...
1993-01-01
ANL`s electric vehicle battery activities for USABC. Progress report, April--September 1992
Energy Technology Data Exchange (ETDEWEB)
The Electrochemical Technology Program at Argonne National Laboratory (ANL) provides advanced battery R&D; technology transfer to industry; technical analyses, assessments, modeling, and databases; and independent testing and post-test analyses of advanced batteries. These capabilities and services are being offered to the US Advanced Battery Consortium (USABC) and Cooperative Research and Development Agreements (CRADA) are being negotiated for USABC-sponsored work at ANL. A small portion of DOE`s cost share for USABC projects has been provided to ANL to continue R&D and testing activities on key technologies that were previously supported directly by DOE. This report summarizes progress on these USABC projects during the period of April I through September 30, 1992. In this report, the objective, background, technical progress, and status are described for each task. The work is organized into the following task areas: 1.0 Lithium/Sulfide Batteries; 2.0 ...
1992-12-31
ANL's electric vehicle battery activities for USABC. [US Advanced Battery Consortium (USABC)
Energy Technology Data Exchange (ETDEWEB)
The Electrochemical Technology Program at Argonne National Laboratory (ANL) provides advanced battery R D; technology transfer to industry; technical analyses, assessments, modeling, and databases; and independent testing and post-test analyses of advanced batteries. These capabilities and services are being offered to the US Advanced Battery Consortium (USABC) and Cooperative Research and Development Agreements (CRADA) are being negotiated for USABC-sponsored work at ANL. A small portion of DOE's cost share for USABC projects has been provided to ANL to continue R D and testing activities on key technologies that were previously supported directly by DOE. This report summarizes progress on these USABC projects during the period of April I through September 30, 1992. In this report, the objective, background, technical progress, and status are described for each task. The work is organized into the following task areas: 1.0 Lithium/Sulfide Batteries; 2.0 ...
1992-01-01
Energy Technology Data Exchange (ETDEWEB)
The main objective of nuclear liability law is the compensation of victims of a possible nuclear incident. However, an adequate nuclear liability law is just as important for nuclear industry, in particular the supply industry - including suppliers of know-how and consultants. Without such a law, the liability risk would be incalculable and industry would not be ready to supply to nuclear installations or nuclear activities. This applies especially to programmes which aim at improving nuclear safety in Eastern Europe. Key elements are the exclusive concentration of liability onto the operator of a nuclear installation (channelling of liability) and the channelling of lawsuits onto one single competent court in one single country. There are recent examples: The negotiations on the management of nuclear waste, including submarines, in Northern Russia and the negotiations within the framework of the East Asian project of the Korean Peninsula ...
2002-09-01
Modelling and simulation of rate-based mechanistic model for CO{sub 2} capture
Energy Technology Data Exchange (ETDEWEB)
The electric power industry can use the carbon dioxide absorption process to capture carbon from high-volume flue gas. However, the current cost of the process is too high due to the approximation method used in process design. The absorption column is typically designed with parameters that are assumed to be constant over the whole length of the column, resulting in an oversized unit. This approximation method is no longer valid given new environmental and economic concerns. In order to develop an accurate column design for high-efficiency carbon dioxide (CO{sub 2}) capture, it is necessary to understand the phenomena taking place in the system. A mechanistic model is presented for a robust absorber design that takes into account mass-transfer and hydrodynamic behaviour within the CO{sub 2} absorption columns. The capture performance of a packed column under a wide range of design and operating conditions was determined using a model based on the kinetics and ...
2003-07-01
Mechanistic studies of ethylene biosynthesis in higher plants
Energy Technology Data Exchange (ETDEWEB)
Ethylene is a plant hormone that elicits a wide variety of responses in plant tissue. Among these responses are the hastening of abscission, ripening and senescence. In 1979 it was discovered that 1-amino-1-cyclopropane carboxylic acid is the immediate biosynthetic precursor to ethylene. Given the obvious economic significance of ethylene production the authors concentrated their studies on the conversion of ACC to ethylene. They delved into mechanistic aspects of ACC oxidation and they studied potential inhibitors of ethylene forming enzyme (EFE). They synthesized various analogs of ACC and found that EFE shows good stereodiscrimination among alkyl substituted ACC analogs with the 1R, 2S stereoisomer being processed nine times faster than the 1S, 2R isomer in the MeACC series. They also synthesized 2-cyclopropyl ACC which is a good competitive inhibitor of EFE. This compound also causes time dependent loss of EFE activity leading us to believe it is an ...
1986-01-01
Characterization of VPO ammoxidation catalysts by in situ methods
Energy Technology Data Exchange (ETDEWEB)
In-situ methods are well known as powerful tools in studying catalyst formation processes, their solid state properties under working conditions and the interaction with the feed, intermediates and products to reveal reaction mechanisms. This paper gives a short overview on results of intense studies using in-situ techniques to reveal VPO catalyst generation processes, interaction of educts, intermediates and products with VPO catalyst surfaces and mechanistic insights. Catalytic data of the ammoxidation of toluene on different VPOs complete these findings. The precursor-catalyst transformation processes were preferently investigated by in-situ XRD, in-situ Raman and in-situ ESR spectroscopy. The interaction of aromatic molecules and intermediates, resp., and VPO solid surfaces was followed by in-situ ESR and in-situ FTIR spectroscopy. Mechanistic information was mainly obtained using in-situ FTIR spectroscopy and the ...
1998-12-31
Cytosine methylation in DNA is a major epigenetic signal, and plays a central role in propagating chromatin status during cell division. However the mechanistic links between DNA methylation and histone methylation are poorly understood. A multi-domain protein UHRF1 (ubiquitin-like, containing PHD and RING finger domains 1) is required for DNA CpG maintenance methylation at replication forks, and mouse UHRF1-null cells show enhanced susceptibility to DNA replication arrest and DNA damaging agents. Recent data demonstrated that the SET and RING associated (SRA) domain of UHRF1 binds hemimethylated CpG and flips 5-methylcytosine out of the DNA helix, whereas its tandom tudor domain and PHD domain bind the tail of histone H3 in a highly methylation sensitive manner. We hypothesize that UHRF1 brings the two components (histones and DNA) carrying appropriate markers (on the tails of H3 and hemimethylated CpG sites) ready to be assembled into a nucleosome after ...
2009-01-01
International Nuclear Information System (INIS)
The rates of spontaneous interbilayer and transbilayer exchange of ["3H]dimyristoylphosphatidylcholine (["3H]DMPC) were examined in the DMPC and DMPC/dimyristoylphosphatidylethanolamine (DMPE) large unilamellar vesicles in the liquid-crystalline-, gel-, and mixed-phase states. DMPC desorption rates from either gel or liquid-crystalline phases containing DMPE are very similar to the corresponding rates from pure DMPC gel or liquid-crystalline phases. The authors proposed that the DMPC/DSPC behavior results from packing defects in gel phases composed of both DMPC and DSPC molecules because of the four-carbon difference in the acyl chain lengths of the two species. The present results strongly support this hypothesis because no such anomalous behavior is observed in DMPC/DMPE, which is similar to DMPC/DSPC in phase behavior but does not have the chain length difference. These results are not consistent with lipid headgroup dehydration as the major energetic barrier to flip-flop but rather ...
Source term attenuation by water in the Mark I boiling water reactor drywell
Energy Technology Data Exchange (ETDEWEB)
Mechanistic models of aerosol decontamination by an overlying water pool during core debris/concrete interactions and spray removal of aerosols from a Mark I drywell atmosphere are developed. Eighteen uncertain features of the pool decontamination model and 19 uncertain features of the model for the rate coefficient of spray removal of aerosols are identified. Ranges for values of parameters that characterize these uncertain features of the models are established. Probability density functions for values within these ranges are assigned according to a set of rules. A Monte Carlo uncertainty analysis of the decontamination factor produced by water pools 30 and 50 cm deep and subcooled 0--70 K is performed. An uncertainty analysis for the rate constant of spray removal of aerosols is done for water fluxes of 0.25, 0.01, and 0.001 cm{sup 3} H{sub 2}O/cm{sup 2}-s and decontamination factors of 1.1, 2, 3.3, 10, 100, and 1000.
1993-09-01
Energy Technology Data Exchange (ETDEWEB)
The most relevant aspects of research and service experience with environmentally-assisted cracking (EAC) of carbon (C) and low-alloy steels (LAS) in high-temperature (HT) water are reviewed, with special emphasis on the primary pressure boundary components of boiling water reactors (BWRs). The main factors controlling the susceptibility to EAC under light water reactor (LWR) conditions are discussed with respect to crack initiation and crack growth. The adequacy and conservatism of the current BWRVIP-60 stress corrosion cracking (SCC) disposition lines (DLs), ASME III fatigue design curves, and ASME XI reference fatigue crack growth curves, as well as of the GE EAC crack growth model are evaluated in the context of recent research results. The operating experience is summarized and compared to the experimental/mechanistic background knowledge. Finally, open questions and possible topics for further research are identified. Laboratory investigations revealed ...
2005-11-15
Energy Technology Data Exchange (ETDEWEB)
Following the successful application of hydrostatic pressure in mechanistic investigations of organic reactions, chemists have launched a vigorous effort to apply this tool to substitution reactions of coordination compounds. The authors began to study pressure effects in the NMR spectra of keton-lanthanide combination with the hope that the increase shifts anticipated might enhance the utility of the method, perhaps even expand its applicability to new classes of compounds. 5-Phenyl- and 5-tert-butyladamantan-2-one, piperidine, tetrahydrofuran, and cyclopentanol exhibited pressure-reduced lanthanide-induced shifts with Eu(fod)/sub 3/; Yb(fob)/sub 3/ and the shielding reagent Pr(fod)/sub 3/ showed the same effect with adamantanone. Solvent variations (CD/sub 2/Cl/sub 2/, CCl/sub 4/) caused minor changes in the magnitude of these shifts but did not reverse any. With the objective of learning whether these effects are due to a suppressed equilibrium population or to ...
1987-11-11
Plasma chemistry in wire chambers
Energy Technology Data Exchange (ETDEWEB)
The phenomenology of wire chamber aging is discussed and fundamentals of proportional counters are presented. Free-radical polymerization and plasma polymerization are discussed. The chemistry of wire aging is reviewed. Similarities between wire chamber plasma (>1 atm dc-discharge) and low-pressure rf-discharge plasmas, which have been more widely studied, are suggested. Construction and use of a system to allow study of the plasma reactions occurring in wire chambers is reported. A proportional tube irradiated by an {sup 55}Fe source is used as a model wire chamber. Condensable species in the proportional tube effluent are concentrated in a cryotrap and analyzed by gas chromatography/mass spectrometry. Several different wire chamber gases (methane, argon/methane, ethane, argon/ethane, propane, argon/isobutane) are tested and their reaction products qualitatively identified. For all gases tested except those containing methane, use of hygroscopic filters to remove trace water and ...
1990-05-01
Photochemical energy conversion by membrane-bound photoredox systems. Final report
Energy Technology Data Exchange (ETDEWEB)
This project has received DOE support since July 1, 1978. During this period, 40 papers have been published dealing predominantly with chlorophyll-photosensitized electron transfer reactions in a variety of media (solutions, polymer films, lipid bilayer membranes). The overall theme of this work has been to develop mechanistic strategies f or photochemical energy storage via chlorophyll, using the green plant photosynthetic system as a paradigm for designing in vitro systems. Microheterogeneous lipid vesicle suspensions allow ready application of time-resolved optical spectroscopy to follow the course of light-induced electron transfer processes. Both the yields and the lifetimes of electron transfer products were markedly improved in the vesicle systems. In subsequent studies, this compartmentalization was favorably manipulated by controlling the electrical charge on the membrane surface, by controlling the solubility properties of the acceptors, by varying the ...
1994-06-16
Parametric study of pipe whip analysis
Energy Technology Data Exchange (ETDEWEB)
In the Energy Balance Analysis Model (Standard Review Plan (USNRC, 1981), Section 3.6.2, ''Determination of Rupture Locations and Dynamic Effects Associated with the Postulated Rupture of Piping''), time dependence is not considered, and a constant blowdown thrust force is assumed. This force includes an amplification factor of 1.1 to account for potential effects of rebound. Many of the assumptions used in establishing the acceptance criteria, as stated in the Standard Review Plan, were based on engineering judgment and logic intended to assure upper bound design rather than on a mechanistic assessment of actual pipe rupture phenomena and their effects. As a result of the current practice an exceedingly conservative design may be introduced. This report represents a parametric study of the amplification factor to account for rebound effects in the Energy Balance Method. Of the 71 distinct cases we chose for our parametric study, ...
1987-10-01
OZONE PRODUCTION IN THE PHILADELPHIA URBAN AREA DURING NE-OPS 99
International Nuclear Information System (INIS)
As part of the 1999 NARSTO Northeast Oxidant and Particulate Study (NE-OPS) field campaign, the DOE G-1 aircraft sampled trace gases and aerosols in and around the Philadelphia metropolitan area. Twenty research flights were conducted between July 25 and August 11. The overall goals of these flights were to obtain a mechanistic understanding of O(sub 3) production; to characterize the spatial and temporal behavior of photo-oxidants and aerosols; and to study the evolution of aerosol size distributions, including the process of new particle formation. Within the NE-OPS program, other groups provided additional trace gas, aerosol, and meteorological observations using aircraft, balloon, remote sensing, and surface based instruments (Phillbrick et al., 2000). In this article we provide an overview of the G-1 observations related to O(sub 3) production, focusing on the vertical distribution of pollutants. Ozone production rates are calculated using a box model that is ...
Ion movements in cell death: from protection to execution
Scientific Electronic Library Online (English)
Abstract in english Cell death is preceded by severe disruption of inorganic ion homeostasis. Seconds to minutes after an injury, calcium, protons, sodium, potassium and chloride are exchanged between the cell and its environment. Simultaneously, ions are shifted between membrane compartments inside the cell, whereby mitochondria and endoplasmic reticulum play a crucial role. Depending of the type and severity of injury, two mutually exclusive metastable states can be reached, which predict (more) the final outcome. Cells characterized by large increases in cytosolic [Ca2+], [Na+]; and [Mg2+] swell and die by necrosis; alternatively, cells characterized by high [H+]and low [K+], with normal [Na+] and normal to moderate [Ca2+] increases die by apoptosis. The levels of these ions represent central determinants in signaling events leading to cell death. Their movements are explained mechanistically by specific modulation of membrane transport proteins including ...
2002-01-01
Integral severe accident analysis of light water nuclear power plants by IMPACT-SAMPSON code
Energy Technology Data Exchange (ETDEWEB)
The NUclear Power Engineering Corporation (NUPEC) has developed IMPACT-SAMPSON code to analyze integral behavior of light water nuclear power plants under severe accident conditions. IMPACT-SAMPSON's distinguishing features include interconnected hierarchical modules and mechanistic models covering a wide spectrum of scenarios ranging from normal operation to severe accident events, and high-speed simulation on parallel processing computers. The integral plant behaviors of typical PWR and BWR under severe accident conditions have been analyzed with the IMPACT-SAMPSON code. The PWR plant analyzed was the three-loop, steel-dry containment type with 2,440 MWt. The AE accident scenario was supposed, that is, LOCA by 6-inch hot leg failure followed by accumulated water injection, but no ECCS and containment spray activation. The BWR plant analyzed was the 3,293 MWt BWR-5, Mark-II containment type. The TQUV accident scenario was supposed, that is, reactor scram ...
2003-07-01
Energy Technology Data Exchange (ETDEWEB)
This paper describes the development of a computational multiphase fluid dynamics (CMFD) model of the Fischer Tropsch (FT) process in a Slurry Bubble Column Reactor (SBCR). The CMFD model is fundamentally based which allows it to be applied to different industrial processes and reactor geometries. The NPHASE CMFD solver [1] is used as the robust computational platform. Results from the CMFD model include gas distribution, species concentration profiles, and local temperatures within the SBCR. This type of model can provide valuable information for process design, operations and troubleshooting of FT plants. An ensemble-averaged, turbulent, multi-fluid solution algorithm for the multiphase, reacting flow with heat transfer was employed. Mechanistic models applicable to churn turbulent flow have been developed to provide a fundamentally based closure set for the equations. In this four-field model formulation, two of the fields are used to track the gas phase (i.e., ...
2008-11-01
In Vitro Fracture of Human Cortical Bone: Local Fracture Criteria and Toughening Mechanisms
Energy Technology Data Exchange (ETDEWEB)
A micro-mechanistic understanding of bone fracture that encompasses how cracks interact with the underlying microstructure and defines their local failure mode is lacking, despite extensive research on the response of bone to a variety of factors like aging, loading, and/or disease. Micro-mechanical models for fracture incorporating such local failure criteria have been widely developed for metallic and ceramic materials systems; however, few such deliberations have been undertaken for the fracture of bone. In fact, although the fracture event in mineralized tissues such as bone is commonly believed to be locally strain controlled, until recently there has been little experimental evidence to support this widely held belief. In the present study, a series of in vitro experiments involving a double-notch bend test geometry are performed in order to shed further light on the nature of the local cracking events that precede catastrophic fracture in bone and to define ...
2004-08-18
Hardening of ion-irradiated A533B steels investigated with nanoindentation technique
International Nuclear Information System (INIS)
Neutron irradiation embrittlement of reactor pressure vessel (RPV) steels is one of the critical issues on aging management for long term operation of nuclear power plants. Mechanistic understanding of embrittlement is a key to accurate prediction of embrittlement, especially after long term operation where the mechanical test data are sparse. Since matrix hardening is the source of the embrittlement, we focus on matrix hardening of A533B bainitic pressure vessel steel. Bainitic matrix is composed of lath structure made by ferrite and carbides, therefore it is important to understand how this structure affects hardening behavior, and to understand irradiation response of each phase. As the typical dimension of lath structure of A533B is about one micron, nanoindentation technique is suitable for the estimation of hardening of each phase. MV ion accelerators were used for controlled irradiation because MeV ion irradiation can produce defects to the depth greater ...
2008-10-13
Establishing the scientific and mechanistic framework for a GIN (Genetic Improvement Network)
Environmental Research Database
Objectives7. (b) Objectives General background Livestock production accounts for 70% of the agricultural land on the planet. Given that demand for livestock products is expected to double by 2050 it is vital that we identify less polluting ways of production, spanning both intensive and extensive systems. Northern Europe is one of the few parts of the globe where climate change is expected to be neutral or even benefit agricultural productivity. Hence it is likely to make an even more important co [continued...]DescriptionRuminant genetic improvement can play an important role in developing livestock systems that will be sustainable in the future, and produce food in an environmentally friendly manner. Also, genetic improvement of livestock is a particularly cost-effective technology, producing permanent and cumulative changes in performance. Moran et al (2007) showed the very high value of animal and plant genetics research and development in helping to deliver on likely future policy ...
2010-01-31
Dynamic modeling of interfacial structures via interfacial area transport equation
International Nuclear Information System (INIS)
The interfacial area transport equation dynamically models the two-phase flow regime transitions and predicts continuous change of the interfacial area concentration along the flow field. Hence, when employed in the numerical thermal-hydraulic system analysis codes, it eliminates artificial bifurcations stemming from the use of the static flow regime transition criteria. Accounting for the substantial differences in the transport phenomena of various sizes of bubbles, the two-group interfacial area transport equations have been developed. The group 1 equation describes the transport of small-dispersed bubbles that are either distorted or spherical in shapes, and the group 2 equation describes the transport of large cap, slug or churn-turbulent bubbles. The source and sink terms in the right-hand-side of the transport equations have been established by mechanistically modeling the creation and destruction of bubbles due to major bubble interaction mechanisms. In the ...
2005-01-01
International Nuclear Information System (INIS)
Two plant species, Cucurbita pepo and Cucurbita maxima, and two earthworm species, Eisenia fetida and Lumbricus terrestris, were exposed to soil and compost with equivalent p,p'-DDE contamination. Pollutant bioconcentration was equal in plant roots in both media, but translocation was higher in C. pepo. Bioaccumulation by E. fetida was approximately 6- and 3-fold higher than that by L. terrestris in the soil and compost, respectively. For all species, p,p'-DDE uptake was significantly greater from soil than from compost; 7- to 8-fold higher for plant roots and 3- to 7-fold higher for worms. Abiotic desorption from soil was approximately twice that from the compost. When all the data are normalized for organic-carbon content of the media, the contaminant is more tightly bound by soil than compost. Although the risk associated with p,p'-DDE is higher in soil than compost, important mechanistic differences exist in contaminant binding to organic carbon in the two ...
2007-07-01
Degradation mechanisms and accelerated aging test design
Energy Technology Data Exchange (ETDEWEB)
The fundamental mechanisms underlying the chemical degradation of polymers can change as a function of environmental stress level. When this occurs, it greatly complicates any attempt to use accelerated tests for predicting long-term material degradation behaviors. Understanding how degradation mechanisms can change at different stress levels facilitates both the design and the interpretation of aging tests. Oxidative degradation is a predominant mechanism for many polymers exposed to a variety of different environments in the presence of air, and there are two mechanistic considerations which are widely applicable to material oxidation. One involves a physical process, oxygen diffusion, as a rate-limiting step. This mechanism can predominate at high stress levels. The second is a chemical process, the time-dependent decomposition of peroxide species. This leads to chain branching and can become a rate-controlling factor at lower stress levels involving time-scales ...
1985-01-01
DEFF Research Database (Denmark)
The objectives of this study were to characterize the changes of VOC material emission profiles over time and develop a method to account for such changes in order to enhance a source identification technique that is based on the measurements of mixed air samples and the emission signatures of individual building materials determined by PTRMS. Source models, including powerlaw model, doubleexponential decay model and mechanistic diffusion model, were employed to track the change of individual material emission signatures by PTRMS over a ninemonth period. Samples of nine typical building materials were tested individually for nine months and later in combination to obtain actual mixture emissions. VOC emissions from each material were measured in a 50liter smallscale chamber. Chamber air was sampled by PTRMS over a 28day period to determine their emission rate decay characteristics as well as to establish the initial profile of emission signatures unique to ...
2011-01-01
CORMLT modeling of severe fuel damage in postulated accidents
Energy Technology Data Exchange (ETDEWEB)
Recently, the capabilities of the CORMLT code, which was designed to predict heatup, degradation, and meltdown of core and Reactor Pressure VEssel (RPV) internals during postulated severe accidents, were enhanced to enable tracking of individual fission product species during core meltdown. In addition, a mechanistic treatment of the release and flow of molten materials was developed to replace the engineering models developed earlier. In the present paper, the improved models are described and predictions of melt progression for a postullated accident sequence (TMLB') are discussed. A key issue in the new modeling is the mechanical behavior of fuel pellet stacks during run-off of molten cladding. One view is that capillary forces result in ''welding'' of porous fuel, thereby promoting free-standing pellet stacks; another is that rubblization and slumping of fuel take place. Results are reported for the first view point ...
1987-01-01
Energy Technology Data Exchange (ETDEWEB)
The present paper is concerned with development and application of a so-called Effective Convection Model (ECM), which aims to provide a detailed, mechanistic description of heat transfer processes in a BWR lower plenum. The ECM is a Computational Fluid Dynamics (CFD)-like tool which employs a simpler and more effective approach to compute heat transfer by solving only energy conservation equation instead of solving the full set of Navier-Stokes and energy equations by a CFD code. We implement the ECM in a CFD code (Fluent), with detailed description of the ECM development, implementation and validation. A dual approach is used to validate the ECM, namely validation against experimental data and against heat transfer results obtained by CFD predictions in the same geometries and conditions. Insights gained from CFD simulations are also used to improve ECM. The ECM capability as an effective tool to simulate heat transfer of an internally heated volume in ...
2007-07-01
International Nuclear Information System (INIS)
The present paper is concerned with development and application of a so-called Effective Convection Model (ECM), which aims to provide a detailed, mechanistic description of heat transfer processes in a BWR lower plenum. The ECM is a Computational Fluid Dynamics (CFD)-like tool which employs a simpler and more effective approach to compute heat transfer by solving only energy conservation equation instead of solving the full set of Navier-Stokes and energy equations by a CFD code. We implement the ECM in a CFD code (Fluent), with detailed description of the ECM development, implementation and validation. A dual approach is used to validate the ECM, namely validation against experimental data and against heat transfer results obtained by CFD predictions in the same geometries and conditions. Insights gained from CFD simulations are also used to improve ECM. The ECM capability as an effective tool to simulate heat transfer of an internally heated volume in ...
2007-05-13
Energy Technology Data Exchange (ETDEWEB)
The possibility of improving the cold formability of wrought magnesium alloys is considered in light of their good hot forming characteristics. Magnesium alloy AZ31B sheet is selected as a model system. Parameters affecting formability, such as strain hardening rate, strain rate sensitivity, and the degree of anisotropy are examined systematically by conducting tensile tests over a range of temperatures (room temperature to 250 C) and strain rates (1 x 10{sup -5} to 0.1 s{sup -1}). The plastic anisotropy and deformation texture evolution are examined in samples aligned with the sheet rolling and transverse directions. Polycrystal plasticity simulations using a viscoplastic self-consistent (VPSC) formulation are used to model the observed anisotropy and texture evolution. The adjustable parameters in the model are the relative critical resolved shear stresses of the dislocation mechanisms known to operate within magnesium. The experimental results suggest that an increased strain rate ...
2003-07-01
British Library Electronic Table of Contents (United Kingdom)
Pyrrolo[2,1-c][1,4]benzodiazepine (PBD) chemicals are antitumor antibiotics inhibiting nucleic acid synthesis. An indole carboxylate-PBD hybrid with six-carbon spacer structure (IN6CPBD) has been previously demonstrated to induce melanoma cell apoptosis and reduce metastasis in mouse lungs. This study aimed at investigating the efficacy of the other hybrid compound with four-carbon spacer (IN4CPBD) and elucidating its anti-metastatic mechanism. Human melanoma A375 cells with IN4CPBD treatment underwent cytotoxicity and apoptosis-associated assays. Transwell migration assay, Western blotting, and ELISA were used for mechanistic study. IN4CPBD exhibited potent melanoma cytotoxicity through interrupting G1/S cell cycle progression, increasing DNA fragmentation and hypodipoidic DNA contents, a...
2011-01-01
The advanced manufacturing science and technology program. FY 95 Annual Report
Energy Technology Data Exchange (ETDEWEB)
This is the Fiscal Year 1995 Annual Report for the Advanced Manufacturing Science and Technology (AMST) sector of Los Alamos Tactical Goal 6, Industrial Partnering. During this past fiscal year, the AMST project leader formed a committee whose members represented the divisions and program offices with a manufacturing interest to examine the Laboratory`s expertise and needs in manufacturing. From a list of about two hundred interest areas, the committee selected nineteen of the most pressing needs for weapon manufacturing. Based upon Los Alamos mission requirements and the needs of the weapon manufacturing (Advanced Design and Production Technologies (ADaPT)) program plan and the other tactical goals, the committee selected four of the nineteen areas for strategic planning and possible industrial partnering. The areas selected were Casting Technology, Constitutive Modeling, Non-Destructive Testing and Evaluation, and Polymer Aging and Lifetime Prediction. For each area, the AMST ...
1996-03-01
International Nuclear Information System (INIS)
The UK fully supports the objective of the Joint Convention on the Safety of Spent Fuel Management and on the Safety of Radioactive Waste Management to achieve and maintain a high level of safety worldwide in spent fuel and radioactive waste management, through the enhancement of national measures and international co-operation, including where appropriate, safety-related co-operation. The UK's Health and Safety Executive, through its Nuclear Safety Directorate (NSD), has been committed to the Convention since the initial negotiations to set up the Convention and provided the president of the first review meeting in 2003. It would be wrong of any nation to believe that they have all the best solutions to managing spent fuel and radioactive waste. The process of compiling reports for the Convention review meetings provides a structured process through which every contracting party can review its provisions against a common set of standards and identify for itself ...
In the Savannah River Site's (SRS') Solid Waste Management Program, a key to success is the Public Involvement Program. The Solid Waste Division at SRS manages the site's transuranic, low-level, mixed, and hazardous wastes. All decisions associated with management of this waste are of interest to the public and successful program implementation would be impossible without a vigorous public involvement program. The SRS Solid Waste Division (SWD) and its Department of Energy (DOE) customer developed, implemented, and maintain a comprehensive public participation and communications program. It is staffed by public participation and technical specialists to ensure information is presented in a manner that is technically accurate while being tailored for understanding by people without a technical background. The program provides the public with accurate, complete, timely information and early meaningful participation opportunities. It also fulfills the public ...
2003-02-27
New trends in electricity pricing in Sweden from a utility perspective
Energy Technology Data Exchange (ETDEWEB)
Sweden is facing a re-structured electricity market beginning January 1, 1996, implying full competition in the purchasing and selling of electricity. The transmission and distribution of electricity will remain as a franchised monopoly and this business has to be strictly separated from the electricity trading. In the monopolistic environment, pricing of electricity has been based on more or less relevant costs and a resonable rate of return. The energy charges have reflected the system short range marginal costs while the demand and fixed charges have been adapted to give a total cost level corresponding to the system average cost. Tariffs of this type, known as time-of-use tariffs, have stimulated peak shaving during peak load (high cost hours) and valley filling during low load (low cost hours), increasing the load factor. Restructuring will influence the pricing in several ways. Pricing of transmission and distribution services will be based on costs and will be supervised by a ...
1996-03-01
Energy Technology Data Exchange (ETDEWEB)
Two of the working sessions of the meeting were devoted to aspects of international atomic energy law; the international character of the meeting was also reflected by the home countries of the members of the panel discussion concluding the working sessions. There was substantial reason to put emphasis on the international dimension of the topics discussed. In June 1994, the Nuclear Safety Convention had been signed in Vienna by diplomatic representatives of the signatory countries, and this Convention marks a signpost in the history of international atomic energy law. At the time the meeting was held, negotiations for improving the international nuclear lability law, which had been dragging on since 1989, had come to a stalemate. The meeting offered a suitable forum for taking a scientific approach to tackle the complex problems involved in reshaping the law on nuclear safety and nuclear liability. The third working session of the meeting has been discussing ...
1995-12-31
Initial results of the CD-1 reliable multicast experiment
Energy Technology Data Exchange (ETDEWEB)
During the past year, an experiment has been underway to test use of reliable multicast capabilities for transmission of continuous data in the Global Communication Infrastructure. For the experiment a version of the CD-1 protocol was multicast enabled. The experiment has demonstrated the feasibility of transmitting data in a multicast mode over the GCI. In the case of the Comprehensive Nuclear Test-Ban Treaty the sender could be the station and the receivers the International Data Center (IDC) and one or more National Data Centers (NDC). The potential advantages of multicasting include (a) the timely receipt of the data by the IDC and the host NDC and (b) the simultaneous availability of the raw station data at, at least, two locations. The latter, by introducing redundant data paths, decreases the probability of loss of station data due to a potential failure of a single data receiver. This experiment is only one element of a needed more thorough assessment of the reliability and ...
2000-09-29
Energy Technology Data Exchange (ETDEWEB)
The Kyoto Protocol attempts through political negotiations to guide participating industrialized countries' greenhouse gas (GHG) emissions from a positive growing trend, to reach a peak point (or turning point), and then be reduced to a negative growth. That means the relationship between decreasing GHG emissions and economic growth may be described by an inverted-U curve (or called a bell-shaped curve), which is consistent with the concept of the Environmental Kuznets Curve (EKC) hypothesis. This research observed that the economic development and GHG emissions in Economies in Transition (EITs) exhibit a hockey-stick curve trend (or called quasi-L-shape curve), that also generates a lot of 'hot air' which is significant to the implementation of the Kyoto Protocol. In addition, through the analysis of single-country time series data and GDP data, this research demonstrated that statistical data for most of the Annex II countries do not ...
2008-01-15
Energy Technology Data Exchange (ETDEWEB)
The Kyoto Protocol attempts through political negotiations to guide participating industrialized countries' greenhouse gas (GHG) emissions from a positive growing trend, to reach a peak point (or turning point), and then be reduced to a negative growth. That means the relationship between decreasing GHG emissions and economic growth may be described by an inverted-U curve (or called a bell-shaped curve), which is consistent with the concept of the Environmental Kuznets Curve (EKC) hypothesis. This research observed that the economic development and GHG emissions in Economies in Transition (EITs) exhibit a hockey-stick curve trend (or called quasi-L-shape curve), that also generates a lot of 'hot air' which is significant to the implementation of the Kyoto Protocol. In addition, through the analysis of single-country time series data and GDP data, this research demonstrated that statistical data for most of the Annex II countries do not ...
2008-01-15
Enterprise energy management : Part 1
Energy Technology Data Exchange (ETDEWEB)
The needs of large industrial, commercial, and institutional energy consumers are more closely connected with the needs of power utilities and energy services companies, a result of the evolving global energy environment. Consumer choice, competition amongst energy suppliers, and increased demand are brought about in some regions by deregulation. Increasingly, large energy consumers expect high levels of quality and reliability from the energy delivered. As a result, management of the cost and the quality of the energy product and the energy assets that produce, deliver, control and consume it requires different strategies. Three major challenges must be overcome: (1) requirement to support economic and efficient delivery, purchasing and use of energy, (2) requirement to guarantee higher levels of power quality and reliability, and (3) requirement to supply the growing demand for energy while establishing a market-based pricing system. The solution is the enterprise energy management ...
2001-09-01
Energy Technology Data Exchange (ETDEWEB)
In May 1995, the California Public Utilities Commission (CPUC) released two proposals for restructuring the state`s electric power industry. The two proposals follow more than a year of testimony and public comment after the CPUC issued the ``Blue Book`` (CPUC 1994a) on April 20, 1994, which called for retail wheeling to be phased in to all customers over 5 years. The majority proposal, supported by three of the four CPUC commissioners (one seat was vacant when the proposals were released), calls for creating a central pool, or ``poolco``; setting electric prices to reflect true costs of service, or ``real-time pricing``; and allowing parties to negotiate ``contracts for differences`` between the pool price and the contract price. The minority proposal, sponsored by Commissioner Jesse Knight, calls for retail wheeling, or ``direct access,`` and for utilities to divest or spin off their generating assets. This paper presents a summary of the major provisions of the ...
1995-11-01
Energy Technology Data Exchange (ETDEWEB)
Passage through dams is a major source of mortality of anadromous juvenile salmonids because some populations must negotiate up to eight dams in Columbia and Snake rivers. Dams cause direct mortality when fish pass through turbines, but dams may also cause indirect mortality by altering migration conditions in rivers. Forebays immediately upstream of dams have decreased the water velocity of rivers and may contribute substantially to the total migration delay of juvenile salmonids. Recently, Coutant (2001a) suggested that in addition to low water velocities, lack of natural turbulence may contribute to migration delay by causing fish to lose directional cues. Coutant (2001a) further hypothesized that restoring turbulence in dam forebays may reduce migration delay by providing directional cues that allow fish to find passage routes more quickly (Coutant 2001a). Although field experiments have yielded proof of the concept of using induced turbulence to guide fish to ...
2005-07-01
Resource Management in Broadband Communication Networks
DEFF Research Database (Denmark)
This thesis - Resource Management in Broadband Communication Networks - deals with different ways of optimizing the available resources of data- or telecommunication networks. Especially topics like optimal routing, load balancing and fast recovery of routes in case of link failures are covered. The first part gives a brief description of some of the existing protocols for routing and controlling resources, such as RSVP, OSPF, BGP, PNNI, etc. The remaining part concerns the following two fundamentally different approaches to resource management etc.: - Software agents - Simulated ants In the beginning of the part concerning software agents a description of what exactly constitutes software agents, according to the scientists and according to the organization, FIPA is given. After this, the main results from the IMPACT project are presented. The IMPACT project is an EU-project that aimed at developing a demonstration platform, where software agents handled virtually all aspects of ...
2003-01-01
Energy Technology Data Exchange (ETDEWEB)
The focus of this study is on the preparatory detection of uncertain net greenhouse gas (GHG) emission changes (also termed emission signals) under the Kyoto Protocol. The crucial question to be addressed is: How well do we need to know net emissions if we want to detect a specified emission signal after a given time? No restrictions exist as to what concerns the net emitter, which may be any GHG source or sink. Annex I countries are chosen as net emitters, simply for reasons of data availability and because of the excellent possibility of comparing net emitters (inter-country comparison). The countries' emissions - in an increasing number of cases even their uncertainties - are available permitting the application of preparatory signal detection techniques, which are suited to address the aforementioned question. We currently discuss four hierarchically-ordered detection concepts to assess emission signals in a preparatory manner, that is, at two predefined points in time, t1 ...
2004-06-14
FIBROUS MONOLITH WEAR RESISTANT COMPONENTS FOR THE MINING INDUSTRY
Energy Technology Data Exchange (ETDEWEB)
A set of materials property data for potential wear resistant materials was collected. These materials are designated for use as the ''core'' materials in the Fibrous Monolith structure. The material properties of hardness, toughness, thermal conductivity and cost were selected as determining factors for material choice. Data for these four properties were normalized, and weighting factors were assigned for each property to establish priority and evaluate the effects of priority fluctuation. Materials were then given a score based on the normalized parameters and weighting values. Using the initial estimates for parameter priority, the highest ranking material was tungsten carbide, with diamond as the second ranked material. Several materials were included in the trade study, and five were selected as promising ''core'' materials to include in this effort. These materials are tungsten carbide, diamond, boron ...
2001-08-15
Transcriptional regulation in Drosophila: the post-genome challenge.
Drosophila melanogaster has long been at the forefront of studies of transcriptional regulation in animals. Many fundamental ideas--such as cis control elements that act over long distances, the regulation of development by hierarchical cascades of transcription factors, dosage compensation, and position effect variegation--originated from studies of the fruit fly. The recent completion of the euchromatic DNA sequence of Drosophila is another breakthrough. The sequence data highlight important unanswered questions. For example, only one-fifth of the 124 Mb of Drosophila euchromatic DNA codes for protein. The function of the remaining 100 Mb of mostly unique DNA is largely unknown. Some proportion of this non-reading frame DNA must encode the functional recognition sites targeted by the approximately 700 sequence-specific DNA binding proteins that regulate transcription in Drosophila, but what proportion? Most or very little? Promoter sequences by definition contain all of the cis ...
2001-03-01
Energy Technology Data Exchange (ETDEWEB)
Coal liquefaction investigations required the availability of model compounds for mechanistic investigations. Towards this end, IITRI was funded to develop an approach for the synthesis of one of the target compound. This study was carried out in several phases as outlined here. Initial synthetic investigations on obtaining 2-tetrolol was carried out using high pressure and temperature reduction with Raney nickel catalyst. The next step consisted in incorporation of a hydroxymethyelene group at the C-3 position. This was successfully carried out utilizing 2-tetrolol, formaldehyde, and calcium oxide. An alternate improved method was developed using 3-carboxyl-2-naphthol. This required less time, gave a cheer product in higher yield. Efforts at the introduction of a chloromethylene group only yielded polymeric material or starting material in spite of protection the phenolic group by various groups. They synthesis of 3, 5-dimethyl-6- bromobenzyl chloride was ...
1991-11-01
Synthesis of model compounds for coal liquefaction research
Energy Technology Data Exchange (ETDEWEB)
Coal liquefaction investigations required the availability of model compounds for mechanistic investigations. Towards this end, IITRI was funded to develop an approach for the synthesis of one of the target compound. This study was carried out in several phases as outlined here. Initial synthetic investigations on obtaining 2-tetrolol was carried out using high pressure and temperature reduction with Raney nickel catalyst. The next step consisted in incorporation of a hydroxymethyelene group at the C-3 position. This was successfully carried out utilizing 2-tetrolol, formaldehyde, and calcium oxide. An alternate improved method was developed using 3-carboxyl-2-naphthol. This required less time, gave a cheer product in higher yield. Efforts at the introduction of a chloromethylene group only yielded polymeric material or starting material in spite of protection the phenolic group by various groups. They synthesis of 3, 5-dimethyl-6- bromobenzyl chloride was ...
1991-11-01
Recycle of iodine-loaded silver mordenite by hydrogen reduction
In 1977 and 1978, workers at Idaho National Engineering Laboratory (INEL) developed and tested a process for the regeneration and reuse of silver mordenite, AgZ, used to trap iodine from the dissolver off-gas stream of a nuclear fuel reprocessing plant. We were requested by the Airborne Waste Management Program Office of the Department of Energy to perform a confirmatory recycle study using repeated loadings at about 150/sup 0/C with elemental iodine, each followed by a drying step at 300/sup 0/C, then by iodine removal using elemental hydrogen at 500/sup 0/C. The results of our study show that AgZ can be recycled. There was considerable difficulty in stripping the iodine at 500/sup 0/C.; however, this step went reasonably well at 550/sup 0/C or slightly higher, with no apparent loss in the iodine-loading capacity of the AgZ. Large releases of elemental iodine occurred during the drying stage and the early part of the stripping stage. Lead zeolite, which was employed in the original ...
1982-11-01
Propane oxydehydrogenation over molybdate-based catalysts
Energy Technology Data Exchange (ETDEWEB)
Single and binary metal molybdates, supported on silica (80 wt% active phase/20 wt% SiO{sub 2}), having the formula AMoO{sub 4}, where A = Ni, Co, Mg, Mn, and/or Zn, and some ternary molybdates having the formula Ni{sub 0.45}Co{sub 0.45}X{sub 0.066}MoO{sub 4}, where X = P, Bi, Fe, Cr, V, and Ce, were investigated for the oxydehydrogenation of propane to propylene. The reaction is catalytic and is first order in propane disappearance, consistent with the abstraction of a methylene hydrogen being the rate limiting step. Propane conversion and yields of propylene produced vary greatly with the choice of the A metal of the molybdate and the surface area of the catalyst. At 560{degrees}C and atmospheric pressure, the highest propane conversion and highest propylene yields are obtained with NiMoO{sub 4}/SiO{sub 2} (16% at 27% conversion), closely followed by Ni{sub 0.5}Co{sub 0.5}MoO{sub 4}/SiO{sub 2}. The molybdenum content of the compositions greatly influences the catalytic activity and ...
1997-04-15
Energy Technology Data Exchange (ETDEWEB)
The paper demonstrates that the photocatalytic activity of TiO{sub 2} towards the decomposition of gaseous benzene in a batch reactor can be greatly improved by loading TiO{sub 2} on the surface of Sr{sub 2}CeO{sub 4}. The research investigates the optimum loading amount of TiO{sub 2} on Sr{sub 2}CeO{sub 4} in enhancing the photocatalytic activity of TiO{sub 2}. The prepared photocatalyst was characterized by XRD, UV-vis diffuse reflectance and XPS analyses. TiO{sub 2} is loaded on Sr{sub 2}CeO{sub 4} at 773 K. TiO{sub 2}/Sr{sub 2}CeO{sub 4} absorbs much more visible light than TiO{sub 2}. The XPS spectrum shows that there are Ti, O, C, Sr elements on the surface of the TiO{sub 2}/Sr{sub 2}CeO{sub 4}, and that the binding energy value of Ti2p transfers to a lower value. TiO{sub 2}/Sr{sub 2}CeO{sub 4} demonstrates 2.0 times the photocatalytic activity of pure TiO{sub 2}. Based upon these observations, the mechanistic role of Sr{sub 2}CeO{sub 4} in the photocatalytic ...
2007-02-09
Oxidation and ammoxidation of propylene to acrolein and acrylonitrile with bismuth molybdates
Energy Technology Data Exchange (ETDEWEB)
Under appropriate conditions, bismuth molybdates can catalyze a number of transformations of olefins with selective oxidation being of particular importance. Experimental evidence suggests that the propylene is activated to an allylic species by a site associated with the Bi and that the oxidation step occurs at an Mo site. In order to address the mechanistic steps associated with these Mo sites. The authors discuss the chemistry of terminal oxo and imido groups. They find that for surface sites such as 1 about, 2 about and 3 about, the presence of two double bonds leads to a much more active species than those with a single multiple bond. This leads to a situation similar to that in olefin metathesis by high oxidation state Mo catalysis where the (spectator) oxo group species promotes formation of the metallacycle intermediate by formation of a partial Mo==O triple bond that stabilizes the intermediate. Calculations suggest that the magnitude of the spectator oxo ...
1983-09-01
The human olfactomedin 4 gene (OLFM4) encodes an olfactomedin-related glycoprotein. OLFM4 is normally expressed in a limited number of tissues, including the prostate, but its biological functions in prostate are largely unknown. In this study, we found that OLFM4 messenger RNA was reduced or undetectable in prostate cancer tissues and prostate cancer cell lines. To study the effects of OLFM4 on prostate cancer progression, we transfected PC-3 prostate cancer cells with OLFM4 to establish OLFM4-expressing PC-3 cell clones. The OLFM4-expressing PC-3 cell clones were found to have decreased proliferation and invasiveness compared with vector-transfected control PC-3 cells in vitro. In addition, nude mice injected with OLFM4-expressing PC-3 cells demonstrated reduced tumor growth and bone invasion and metastasis compared with mice injected with vector-transfected control cells. Mechanistic studies revealed that OLFM4 may exhibit its anticancer effects through ...
2011-04-05
Natural circulation reactor design safety analysis
This thesis study covers both global performance and local phenomena analyses focusing on natural circulation reactor design safety. Four important topics are included: the global SBWR design safety assessment, important local phenomena investigation, steady and transient natural circulation process study, and two-phase instability analysis. The conceptual design of the SBWR-200 is introduced in this thesis and the global performance of a natural circulation reactor is then assessed using PUMA integral test data and RELAP5 simulations. A safety assessment methodology is developed to evaluate the PUMA integral test data extrapolation and code scalability. The RELAP5 code simulation capability in low-pressure low-flow conditions is also validated. The study shows that the code is capable of predicting the global accident scenario in natural circulation reactors with reasonable accuracy, while failing to reproduce some safety related local phenomena. The natural circulation process is ...
2001-01-01
Molecular events involved in ionizing radiation induced skin carcinogenesis
International Nuclear Information System (INIS)
The process of mouse skin tumor formation is subdivided into three operational stages. These stages include initiation, promotion and progression. Ionizing radiation has been found to be a weak initiating agent in the production of malignant squamous cell carcinomas, a complete carcinogen and an agent effective in causing tumor progression. Four skin tumor histologies have been seen with ionizing radiation: benign papillomas, squamous (SCC) and basal (BCC) cell carcinomas and fibrosarcomas. Distinct non-ras transforming genes have been detected in radiation initiated SCCs. A benign papilloma cell line (308) was used as a model system to study ionizing radiation induced progression. A variant 308 cell line (308 10 Gy 5) derived by irradiation of the parental 308 cell has been characterized. The 308 10 Gy 5 cells unlike the parental 308 cells from malignant tumors in athymic nude mice upon subcutaneous injection. The variant 308 10 Gy 5 cells unlike the parental cells also show by ...
Energy Technology Data Exchange (ETDEWEB)
Recent efforts to identify methods of modeling pitting corrosion damage of high-level radioactive-waste containers are described. The need to develop models that can provide information useful to higher level system performance assessment models is emphasized, and examples of how this could be accomplished are described. Work to date has focused upon physically-based phenomenological stochastic models of pit initiation and growth. These models may provide a way to distill information from mechanistic theories in a way that provides the necessary information to the less detailed performance assessment models. Monte Carlo implementations of the stochastic theory have resulted in simulations that are, at least qualitatively, consistent with a wide variety of experimental data. The effects of environment on pitting corrosion have been included in the model using a set of simple phenomenological equations relating the parameters of the stochastic model to key ...
1993-01-01
Mechanism of enzyme-catalyzed phospho group transfer
Energy Technology Data Exchange (ETDEWEB)
To understand more fully the mechanism of enzyme-catalyzed phospho group transfer, the stereochemical course at phosphorus of four enzymes has been determined. First, using adenosine (..gamma..-(S)-/sup 16/O, /sup 17/O, /sup 18/O)triphosphate as the substrate, the reaction catalyzed by creatine kinase has been found to proceed with overall inversion of configuration at phosphorus. Second, using adenosine (..beta..-(S)-/sup 16/O, /sup 17/O, /sup 18/O)diphosphate as the substrate, the reaction catalyzed by adenylate kinase has been found also to proceed with overall inversion. Third, the reaction catalyzed by phosphoenolpyruvate carboxylase has been studied using ((S/sub p/)-/sup 16/O, /sup 17/O)thiophospoenolpyruvate as the substrate in H/sub 2/ /sup 18/O. Fourth, using adenosine 5'-O-((..gamma..S/sub p/)-..beta gamma..-/sup 17/O,..gamma..-/sup 17/O,/sup 18/O)(3-thiotriphosphate) as the substrate, the reaction catalyzed by pyruvate carboxylase has been shown to proceed with ...
1986-01-01
Kinetic and mechanistic studies of the reactions of CF{sub 3}O radicals with NO and NO{sub 2}
Energy Technology Data Exchange (ETDEWEB)
The reactions of CF{sub 3}O radicals with (1) NO and (2) NO{sub 2} were studied using two different experimental techniques. A laser photolysis/LIF detection method was applied for measuring the rate constants as a function of temperature (T=222-302 K) and total pressure (p{sub tot}=7-107 mbar). Whereas the reaction with (1) NO was found to be independent of temperature and pressure with k{sub 1}=(4.5{+-}1.2) x 10{sup -11} cm{sup 3}s{sup -1}, the reaction with (2) NO{sub 2} was found to be dependent on both of these variables. The temperature dependence of k{sub 2} in the high pressure limit can be given by the expression k{sub 2{infinity}}{sup -}(T)=(8{+-}5) x 10{sup -13} exp ((863{+-}194) K/T) cm{sup 3}s{sup -1}. The product distributions of the two reactions were determined in separate experiments using steady-state photolysis combined with FTIR spectroscopy. For reaction (1) only CF{sub 2}O was found as a reaction product with a yield of 0.93{+-}0.10, independent of temperature. ...
1997-10-01
How to assess risk from combined exposures to radiation and other agents?
Energy Technology Data Exchange (ETDEWEB)
Efforts to assess and quantify deleterious effects from toxicants concentrate mainly on single agents whereas real world environmental and occupational exposures to natural and anthropogenic agents entail quite often the concomitant presence of several toxicants. For occupational important exposure situations, combined exposures to physical and chemical agents such as radon and smoking or asbestos and smoking, respectively, were shown to produce over-additive effects at exposure levels typical for earlier workplaces. Already the elucidation of possible health risks from a single agents, its dependence on exposure level, exposure rates, age at exposure and its expression in time is a complex endeavour. Therefore in the past and the present the main emphasis in radiation protection, toxicology, and public health is on the study and assessment of single toxicants. The existing data base on combined effect is rudimentary, mainly descriptive and rarely covers exposure ranges large enough to ...
1997-03-01
Energy Technology Data Exchange (ETDEWEB)
The use of aqueous methyldiethanolamine (MDEA) for selective removal of hydrogen sulfide from acid gas streams has been studied in a 2 inch column packed with 1/4 inch ceramic Intalox saddles. The column was operated in a counter-current, steady state fashion. The feed gas composition varied between 1 and 5 mole % hydrogen sulfide and between 0 and 50 mole % carbon dioxide. In order to assist the development of packed column absorption models, the rate at which pure carbon dioxide absorbs into 2 M MDEA was measured as a function of pressure, liquid flow rate and packed bed length. The importance of end effects was carefully evaluated. In addition, draining and tracer methods were used to estimate the amount of static holdup present in the column. Using classical draining methods, as much as 50 % of the total holdup was found to be static. However, according to the step decrease in tracer method, less than 5 % of the total holdup was static. Since the step decrease in tracer method ...
1988-01-01
Energy Technology Data Exchange (ETDEWEB)
The interfacial area transport equation dynamically models the two-phase flow regime transitions and predicts continuous change of the interfacial area concentration along the flow field. Hence, when employed in the numerical thermal-hydraulic system analysis codes, it eliminates artificial bifurcations stemming from the use of the static flow regime transition criteria. Accounting for the substantial differences in the transport phenomena of various sizes of bubbles, the two-group interfacial area transport equations have been developed. The group 1 equation describes the transport of small-dispersed bubbles that are either distorted or spherical in shapes, and the group 2 equation describes the transport of large cap, slug or churn-turbulent bubbles. The source and sink terms in the right-hand-side of the transport equations have been established by mechanistically modeling the creation and destruction of bubbles due to major bubble interaction mechanisms. In the ...
2005-07-01
Anisotropic Nd{endash}Fe{endash}B bonded magnets made from HDDR powders (invited)
Energy Technology Data Exchange (ETDEWEB)
Anisotropic Nd{endash}Fe{endash}B magnet powders can be produced by the hydrogenationdecomposition-desorption-recombination (HDDR) process from Nd{endash}Fe@ xnB{endash}Co{endash}M ({ital M}=Ga, Zr, Nb, Hf, and Ta) alloys. The present status of those HDDR powders and the bonded magnets made from them are reviewed with regards to the powder particle size dependence of their magnetic properties, their magnetic thermal stability, and their magnetization behavior. The results of a mechanistic study on the recombination step are also presented. The magnetic properties of the anisotropic HDDR powder depend relatively little on the powder particle size. Bonded magnets with a density of {approximately}6.20 g/cm{sup 3} and a BH{sub max} of 18.5{endash}20.5 MGOe can be produced from anisotropic HDDR powders with particle sizes of below 300 {mu}m diam. The temperature coefficient of the intrinsic coercive force {sub {ital iH}}{sub {ital c}}, of the bonded magnet is ...
1996-04-01
International Nuclear Information System (INIS)
This report seeks to address the role of hydrogen bonding with Bronsted acids and bases in proton-coupled electron transfer (PCET) as it pertains to concerted or stepwise pathways of quinone (Q) and hydroquinone (QH_2) electrochemistry. This study was performed using a series of techniques that included cyclic voltammetry (CV), digital simulations, computational chemistry and "1H NMR. Hydrogen bonding was inferred by a decrease in diffusion coefficient (D) values measured using a pulsed gradient echo- (PGE-) "1H NMR technique. Changes of 40.8% and 37.9% in D values were only noted after the addition of two equivalents of acetate to 1,4-hydroquinone (1,4-QH_2) and catechol (1,2-QH_2), respectively. In contrast, the D values for the addition of selected amines (pyridine, N,N-diisopropylethylamine and triethylamine) changed only 3.2% on average. Quantum mechanical calculations were conducted to determine the pK_a of all quinoid species to serve as a starting point for the determination of ...
2010-09-01
Stream temperature is an important physical characteristic of headwater streams that plays a critical role in the presence and health of juvenile salmonids. Headwater stream temperature was documented in two geomorphic settings on the Kenai Peninsula, Alaska, focusing on the variation in temperature induced by diffuse groundwater discharge and variable air temperature. Eighteen headwater stream reaches were studied in four watersheds, with 11 drainageway sites and seven discharge-slope sites. In drainageway sites, low-gradient streams flow through broad valleys with groundwater-fed fen wetlands; in discharge-slope sites, high-gradient streams flow through narrow valleys with groundwater-fed slope wetlands. At all 18 sites, hourly stream temperatures were measured for one year. At one drainageway and one discharge-slope site, groundwater temperatures, stream stages, and groundwater heads in the local groundwater flow systems were also measured hourly for a year. A process-based, ...
2010-12-01
Energy Technology Data Exchange (ETDEWEB)
As part of a coordinated program, AECL is developing a set of tools to aid with the prediction and management of steam generator performance. Although stress corrosion cracking (of Alloy 800) has not been detected in any operating steam generator, for life management it is necessary to develop mechanistic models to predict the conditions under which stress corrosion cracking is plausible. Therefore, constant extension rate tests were carried out for Alloy 800 under various steam generator crevice chemistry conditions at applied potentials. These tests were designed to evaluate the stress corrosion cracking susceptibility of Alloy 800 under CANDU( steam generator operating conditions. Based on the experimental results, the recommended electrochemical corrosion potential/pH zone for Alloy 800 determined by electrochemical polarization measurements was verified with the respect of stress corrosion cracking susceptibility. The effects of lead contamination on the ...
2006-07-01
Evaluation of SCC susceptibility of alloy 800 under CANDU SG secondary-side conditions
Energy Technology Data Exchange (ETDEWEB)
As part of a coordinated program, AECL is developing a set of tools to aid with the prediction and management of steam generator performance. Although stress corrosion cracking (of Alloy 800) has not been detected in any operating steam generator, for life management it is necessary to develop mechanistic models to predict the conditions under which stress corrosion cracking is plausible. Therefore, constant extension rate tests were carried out for Alloy 800 under various steam generator crevice chemistry conditions at applied potentials. These tests were designed to evaluate the stress corrosion cracking susceptibility of Alloy 800 under CANDU( steam generator operating conditions. Based on the experimental results, the recommended electrochemical corrosion potential/pH zone for Alloy 800 determined by electrochemical polarization measurements was verified with the respect of stress corrosion cracking susceptibility. The effects of lead contamination on the ...
2006-07-01
Evaluation of SCC susceptibility of alloy 800 under CANDU SG secondary-side conditions
International Nuclear Information System (INIS)
As part of a coordinated program, AECL is developing a set of tools to aid with the prediction and management of steam generator performance. Although stress corrosion cracking (of Alloy 800) has not been detected in any operating steam generator, for life management it is necessary to develop mechanistic models to predict the conditions under which stress corrosion cracking is plausible. Therefore, constant extension rate tests were carried out for Alloy 800 under various steam generator crevice chemistry conditions at applied potentials. These tests were designed to evaluate the stress corrosion cracking susceptibility of Alloy 800 under CANDU( steam generator operating conditions. Based on the experimental results, the recommended electrochemical corrosion potential/pH zone for Alloy 800 determined by electrochemical polarization measurements was verified with the respect of stress corrosion cracking susceptibility. The effects of lead contamination on the ...
2006-11-26
Dynamic modeling of interfacial structures via interfacial area transport equation
Energy Technology Data Exchange (ETDEWEB)
Full text of publication follows:In the current thermal-hydraulic system analysis codes using the two-fluid model, the empirical correlations that are based on the two-phase flow regimes and regime transition criteria are being employed as closure relations for the interfacial transfer terms. Due to its inherent shortcomings, however, such static correlations are inaccurate and present serious problems in the numerical analysis. In view of this, a new dynamic approach employing the interfacial area transport equation has been studied. The interfacial area transport equation dynamically models the two-phase flow regime transitions and predicts continuous change of the interfacial area concentration along the flow field. Hence, when employed in the thermal-hydraulic system analysis codes, it eliminates artificial bifurcations stemming from the use of the static flow regime transition criteria. Therefore, the interfacial area transport equation can make a leapfrog improvement in the ...
2004-07-01
A kinetic and mechanistic study of the oxidation of silicon- and thin metal silicide layers
International Nuclear Information System (INIS)
The formation of thin SiO_2 layers on silicon and metal silicides was studied by phase- and thickness measurements with Rutherford back-scattering of 2 MeV alfa particles. Thermal oxidation was done in steam and dry oxygen at temperatures between 750 degrees Celsius and 1 100 degrees Celsius, while SiO_2 formation at room temperature was carried out by anodic oxidation. The study of silicon oxidation was done on Si<100>, Si<111> and amorphous silicon substrates. Thermal oxidation of CoSi_2, CrSi_2, NiSi_2, PtSi and TiSi_2 was investigated. The oxidation rates of the silicides were found to be much higher than for silicon. The oxidation process is also diffusion-limited with a higher oxidation rate for steam as compared to dry oxygen. The silicide layers were found to stay intact during thermal oxidation. A certain amount of structural and chemical instability did appear. Chemical instabiliy was shown by metal oxidation which led to metal atoms being incorporated into the ...
Energy Technology Data Exchange (ETDEWEB)
In order to practice a design-by-analysis of thermohydraulics design of BWR fuel rod bundles, the subchannel analysis would play a major role. There, the immediate concern is improvement in its predictive capability of CHF due in particular to the film dryout (boiling transition phenomena: BT) on the fuel rod surface. Constitutive equations in the subchannel analysis formulation are responsible for the quality of calculated results. The constitutive equations are a result of integration of the local and instantaneous description of two-phase flows over the subchannel control volume. In general, they are expressed in terms of subchannel-control-volume- as well as area-averaged two-phase flow state variables. In principle the information on local and instantaneous physical phenomena taking place inside subchannels must be counted for in the algebraic form of the equations on the basis of a more mechanistic modeling approach. They should include also influences of the ...
2006-07-01
Two-phase flow modeling in the rod bundle subchannel analysis
Energy Technology Data Exchange (ETDEWEB)
Full text of publication follows:In order to practice a design-by-analysis of thermohydraulics design of BWR fuel rod bundles, the subchannel analysis would play a major role. There, the immediate concern is improvement in its predictive capability of CHF due in particular to the film dryout (boiling transition phenomena: BT) on the fuel rod surface. Constitutive equations in the subchannel analysis formulation are responsible for the quality of calculated results. The constitutive equations are a result of integration of the local and instantaneous description of two-phase flows over the subchannel control volume. In general, they are expressed in terms of subchannel-control-volume- as well as area-averaged two-phase flow state variables. In principle the information on local and instantaneous physical phenomena taking place inside subchannels must be counted for in the algebraic form of the equations on the basis of a more mechanistic modeling approach. They ...
2004-07-01
Two-phase flow modeling in the rod bundle subchannel analysis
International Nuclear Information System (INIS)
In order to practice a design-by-analysis of thermohydraulics design of BWR fuel rod bundles, the subchannel analysis would play a major role. There, the immediate concern is improvement in its predictive capability of CHF due in particular to the film dryout (boiling transition phenomena: BT) on the fuel rod surface. Constitutive equations in the subchannel analysis formulation are responsible for the quality of calculated results. The constitutive equations are a result of integration of the local and instantaneous description of two-phase flows over the subchannel control volume. In general, they are expressed in terms of subchannel-control-volume- as well as area-averaged two-phase flow state variables. In principle the information on local and instantaneous physical phenomena taking place inside subchannels must be counted for in the algebraic form of the equations on the basis of a more mechanistic modeling approach. They should include also influences of the ...
2006-01-01
Phase 2 Final Report. IAEA Safeguards: Implementation blueprint of commercial satellite imagery
International Nuclear Information System (INIS)
This document - IAEA Safeguards: Implementation Blueprint of Commercial Satellite Imagery - constitutes the second report from SSC Satellitbild giving a structured view and solid guidelines on how to proceed with a conceivable implementation of satellite imagery to support Safeguards activities of the Agency. This Phase 2 report presents a large number of concrete recommendations regarding suggested management issues, work organisation, imagery purchasing and team building. The study has also resulted in several lists of actions and preliminary project plans with GANT schedules concerning training, hardware and software, as well as for the initial pilot studies. In both the Phase 1 and Phase 2 studies it is confirmed that the proposed concept of a relatively small Imagery Unit using high-resolution data will be a sound and feasible undertaking. Such a unit capable of performing advanced image processing as a tool for various safeguard tasks will give the Agency an effective instrument ...
1989-08-01
Energy Technology Data Exchange (ETDEWEB)
This dissertation is concerned with the development, experimental diagnostics and mathematical modelling and simulation of polymer electrolyte fuel cells (PEFC). The central themes throughout this thesis are the closely interlinked phenomena of mass and charge transfer. In the face of developing a PEFC system for vehicle propulsion these phenomena are scrutinized on a broad range of relevant scales. Starting from the material related level of the membrane and the gas diffusion layer (GDL) we turn to length scales, where structural features of the cell additionally come into play. These are the scale of flow channels and ribs, the single cell and the cell stack followed by the cell, stack, and system development for an automotive power train. In Chapter 3 selected fundamental material models and properties, respectively, are explored that are crucial for the mathematical modelling and simulation of PEFC, as needed in some succeeding parts of this work. First, established mathematical ...
2007-07-01
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