We present the efficient technique to extract the signal of the intermediate mass Higgs boson from the backgrounds at future {gamma}{gamma} colliders. For a clear Higgs detection, it is important to fit the original electron accelerator energy depending on the Higgs mass, to set the polarization of the photonbeams and to apply the efficient b quark tagging method. we demonstrate the extraction of information of Higgs parameters and the new physics from the observable physical quantities. It is clearly shown that a future {gamma}{gamma} collider will have a rich potential for study on the new physics, as well as the Higgs physics. (author).
We present the efficient technique to extract the signal of the intermediate mass Higgs boson from the backgrounds at future #gamma##gamma# colliders. For a clear Higgs detection, it is important to fit the original electron accelerator energy depending on the Higgs mass, to set the polarization of the photonbeams and to apply the efficient b quark tagging method. we demonstrate the extraction of information of Higgs parameters and the new physics from the observable physical quantities. It is clearly shown that a future #gamma##gamma# collider will have a rich potential for study on the new physics, as well as the Higgs physics. (author).
For the preparation of photonic probes for hadron physics the determination of energy and polarization of the photons is essential. In this dissertation in a first part a possibility of the determination of the degree of polarization by use of the asymmetry observables is presented. In a second part a possibility isd discussed to perform an energy and polarization tagging of nearly real photons in electron scattering under small Q{sup 2}. By this method it should be possible to tag billions of photons per second.
We discuss an experimental technique aimed at tagging electron neutrinos in multi-GeV artificial sources on an event-by-event basis. It exploits in a novel manner calorimetric and tracking technologies developed in the framework of the LHC experiments and of rare kaon decay searches. The setup is based on an instrumented decay tunnel equipped with tagging units that intercept secondary and tertiary leptons from the bulk of undecayed pi+ and protons. We show that the taggers are able to reduce the nue contamination originating from K_e3 decays by about one order of magnitude. Only a limited suppression (~60%) is achieved for nue produced by the decay-in-flight of muons; for moderate beam powers, similar performance as for K_e3 can be reached supplementing the tagging system with an instrumented beam dump.
We have studied the signals for a heavy Higgs boson in the processes {gamma}{gamma}{yields}WWWW, and {gamma}{gamma}{yields}WWZZ at a photon linear collider. The results are based on the first complete tree-level calculation for these reactions. We show that, with a forward ``spectator`` W tag, and a central ``spectator`` W veto to suppress backgrounds from transverse W, Z production, the invariant mass spectrum of central WW, ZZ pairs is sensitive to Higgs bosons with a mass up to 1 TeV in a 2-TeV linear collider. ((orig.)).
There are several on-going projects of e"+e"- colliders. If they are constructed, we can convert them into photon-photon (#gamma#-#gamma#) colliders by converting electron beams into #gamma# beams, irradiating laser beams just before the interaction point. In this report we discuss the technical issues on the accelerator.
An overview of different Ion Beam Analysis (IBA) techniques is given. Examples of applications of the PIXE techniques to various types of samples are presented. (author)
The collisions of high energy photons produced at an electron-positron collider provide a comprehensive laboratory for testing QCD, electroweak interactions, and extensions of the standard model. The luminosity and energy of the colliding photons produced by backscattering laser beams is expected to be comparable to that of the primary e"+e"- collisions. In this overview, we shall focus on tests of electroweak theory in photon-photon annihilation, particularly #gamma##gamma##->#W"+W"-, #gamma##gamma##->#Higgs bosons, and higher-order loop processes, such as #gamma##gamma##->##gamma##gamma#, Z#gamma# and ZZ. Since each photon can be resolved into a W"+W"- pair, high energy photon-photon collisions can also provide a remarkably background-free laboratory for studying WW collisions and annihilation. We also review high energy #gamma##gamma# tests of ...
At DORIS II/HASYLAB a vertical beam position control system is in regular operation. It controls the position and angle of a photonbeam simultaneously, and can stabilize beam movements up to frequencies of 0.1 Hz. To suppress beam vibrations up to 50 Hz and above, a prototype beam stabilization system for these frequencies was built and tested successfully. The present beam oscillations at the HASYLAB beamlines are explained, the quality of the beam position control system and the results of the prototype test are presented.
We have studied the effects of temperature fluctuations on the Advanced Light Source (ALS). By modeling the storage ring support structure, we find that fluctuations of {plus minus}2 to 3deg C in the tunnel will cause photonbeam motion of the order of the beam size. Temperature stabilization at this level will allow the residual motion of the photonbeams to be reduced by a second level of active feedback, operating on signals from photonbeam position monitors. Air temperature in the experimental area and the temperature of cooling water serving the beamlines should be constant to {plus minus}1deg C. This will provide a suitable environment for experiments. (orig.).
The beams in electron linear colliders can be converted to nearly monochromatic photonbeams by means of Compton backscattering of laser photons. The electron beams must then be diverted from the interaction point by some means, the best of which seems to be a plasma lens. This paper describes the constraints on the plasma lens in this application and shows how the ablation of solid hydrogen pellets might be able to produce plasmas to satisfy these constraints. ((orig.)).
There are several on-going projects of e{sup +}e{sup -} colliders. If they are constructed, we can convert them into photon-photon ({gamma}-{gamma}) colliders by converting electron beams into {gamma} beams, irradiating laser beams just before the interaction point. In this report we discuss the technical issues on the accelerator.
We present here the concept of a simple one dimensional photonbeam position monitor for use with high power synchrotron radiation beams. It has micron resolution, reasonable linearity in an inexpensive design. Most important, is its insensitivity to diffusely scattered low energy radiation from components upstream of the monitor.
We investigate the possibility of observing strong interactions of longitudinally polarized weak vector bosons in the process {gamma}{gamma}{yields}ZZ at a photon linear collider. We make use of polarization of the photonbeams and cuts on the decay products of the Z bosons to enhance the signal relative to the background of transversely polarized ZZ pairs. We find that the background overwhelms the signal unless there are strong resonant effects, as for instance from a technicolor analogue of the hadronic f{sub 2}(1270) meson. ((orig.)).
We investigate the possibility of observing strong interactions of longitudinally polarized weak vector bosons in the process {gamma}{gamma} {yields} ZZ at a photon linear collider. We make use of polarization of the photonbeams and cuts on the decay products of the Z bosons to enhance the signal relative to the background of transversely polarized ZZ pairs. We find that the background overwhelms the signal unless there are strong resonant effects, as for instance from a technicolor analogue of the hadronic f{sub 2}(1270) meson.
A method for calculation of absorbed dose distributions in three dimensions for 1-20 MeV photons is presented. The method uses convolution/superposition of photon fluence distributions with energy scattering kernels. Results for Co-60 and X-ray beams in homogeneous and inhomogeneous media are compared with measurements. Good agreement is found between calculations and measurements. 8 refs.; 3 figs.
The implementation of the convolution/superposition method in real dose planning situations is considered. The modelling of photon spectra, the use of patient and treatment setup information, and the calculation of the photon energy released in a patient are detailed. A comparison is made between the approaches of calculating the relative dose directly and using a factor derived from measurements to correct the calculated relative dose. 13 refs.; 7 figs.
A new scheme of the longitudinal emittance measurement for high energy negative ion beam is proposed. The energy distribution of the detached electron from the negative ions by the photodetachment process, if the photon energy is almost equal to the electron binding energy of the negative ion (=electron affinity of the atom), reflects that of the original negative ions. Therefore, by introducing the photon in a short width comparing with the bunch width of the negative ion beam, the longitudinal energy distribution of each phase of the beam, that is the longitudinal emittance, can be measured. (author).
The Monte Carlo method is used to analyse the dose fall-off at the exit surface of a megavoltage photonbeam. The convolution/superposition method of dose calculation using Monte-Carlo-generated homogeneous photon kernels is shown to be in error for exit dose calculation. Instead, photon kernels that incorporate modelling of the exit surface were generated, also using Monte Carlo, to analyse the problem, and the calculated dose fall-off using these kernels agrees well with measured data. In addition, the physics underlying the characteristics of the dose fall-off is analysed based on complete Monte Carlo modelling. Practical improvements to the convolution/superposition method are suggested. (Author).
In the convolution/superposition method of photonbeam dose calculations, inhomogeneities are usually handled by using some form of scaling involving the relative electron densities of the inhomogeneities. In this paper the accuracy of density scaling as applied to primary electrons generated in photon interactions is examined. Monte Carlo calculations are compared with density scaling calculations for air and cork slab inhomogeneities. For individual primary photon kernels as well as for photon interactions restricted to a thin layer, the results can differ significantly, by up to 50%, between the two calculations. However, for realistic photonbeams where interactions occur throughout the whole irradiated volume, the discrepancies are much less severe. The discrepancies for the kernel calculation are attributed to the scattering ...
A facility for studying photon-neutron reactions under a braking #gamma#-beam with an energy of up to 26 MeV from a betratron includes Saratov-2, SM-4A, and IBM AT-386 microcomputers. Neutron detectors, pulsed braking radiation dosimeters, and the devices to control the betatron energy are described.
Photonic band gap structures with single or multiple defects show potential for use in single-beam and multi-beam klystrons and particle accelerators. The primary concerns are the coupling between the modes at each individual defect site and the damping of unwanted higher order modes. A conceptual design of a PBG based, multi-beam klystron and methods to damp HOMs and to cool and tune the structure are presented.
Stabilization of the particle beam position with respect to the focusing optics in the third generation synchrotron light sources is crucial to achieving low emittance and high brightness. For this purpose, global and local beam orbit correction feedbacks will be implemented in the APS storage ring. In this article, the authors discuss application of digital signal processing to particle/photonbeam position feedback using the PID (proportional, integral, and derivative) control algorithm.
Orbit correction is now routinely performed at the few-micron level in the Advanced Photon Source (APS) storage ring. Three diagnostics are presently in use to measure and control both AC and DC orbit motions: broad-band turn-by-turn rf beam position monitors (BPMs), narrow-band switched heterodyne receivers, and photoemission-style x-ray beam position monitors. Each type of diagnostic has its own set of systematic error effects that place limits on the ultimate pointing stability of x-ray beams supplied to users at the APS. Limiting sources of beam motion at present are magnet power supply noise, girder vibration, and thermal timescale vacuum chamber and girder motion. This paper will investigate the present limitations on orbit correction, and will delve into the upgrades necessary to achieve true sub-micron beam stability.
The spectral energy-dependence of the radiation-induced ESR signal has been studied in ovine cortical bone. Crushed bone samples were irradiated using photonbeams with effective energies in the range from 0.06 to 6 MeV, and electron beams with mean energies in the range from 2 to 10 MeV. The photon and electron data were normalized to a dose to bone of 50 Gy and the results are reported as response relative to the ESR signal for photon irradiation at 1.25 MeV ("6"0Co). The photon irradiation results show that the ESR response is greatest at low energies with a relative value of 1.2 at 0.06 MeV. The relative response decreases, as the energy increases, to approximately 0.85 in the region of 2 to 3 MeV. These variations in the relative ESR responses are significantly less than the ESR energy-dependent responses reported in the literature for human tooth enamel ...
We present methods to measure the beam polarizations and the luminosity of [gamma][gamma] colliders at TeV energy scale. The beam polarizations of a [gamma][gamma] collider can easily be monitored by comparing the numbers of events of the processes [gamma][gamma] [yields] l[sup +]l[sup -] and [gamma][gamma] [yields] W[sup +] W[sup -], where l means e or [mu]. The luminosity of a [gamma][gamma] collider is also measurable by the event rate of W boson pair productions and the light lepton pair productions. (orig.)
Little clinical evidence has been provided to show the minimization of radiation resistance of tumors using high linear energy transfer radiation. We therefore investigated the radiobiological and molecular pathological aspects of carbon beam therapy. A total of 27 patients with squamous cell carcinoma (SCC) of the cervix were treated using a carbon beam and 50 control patients with SCC of the cervix using a photonbeam. The expression of Ki-67, p53, and p27 proteins before radiotherapy and 5 and 15 days after therapy initiation were investigated using immunohistochemistry. Similar changes were observed in Ki-67 labeling index (LI) and p53 LI during carbon and photonbeam therapies. However, for carbon beam therapy, the mean p27 LI significantly decreased from 25.2% before treatment to 18.6% on the 5th day after treatment initiation, ...
We report on aging measurements of a photon detector candidate for the HERA-B RICH. The prototype, a proportional wire chamber operated with TMAE, was mounted on an argon filled test-beam RICH and was aged by UV light at rates we expect in HERA-B. We monitored gain and current continuously, and checked the chamber with Cherenkov photons at regular intervals. The number of detected photons/track (projected to 2.75 m C sub 4 F sub 1 sub 0 in HERA-B) dropped from 26 to 11 after two days of aging - well below the 20 required for pi/K separation. Based on these results, HERA-B decided to use multi-anode PMTs as photon detectors in the RICH.
Heavy Ion Collisions at RHIC and LHC energies are potentially an interesting laboratory for the study of QED. In these collisions, a Heavy Ion in one beam sees a highly Lorentz contracted electric field due to an oncoming beam particle. The Electric field reaches a maximum value of E {approx_equal} {gamma}{sub eff} {center_dot} Z {center_dot} e/b{sup 2}, where the apparent Lorentz factor, {gamma}{sub eff} = 2 {center_dot} {gamma}{sub beam}{sup 2} - 1. The collision may be viewed in terms of a flux of photons colliding with a stationary ion target using the equivalent photon approximation, originally introduced by Fermi in 1924. We show that the cross section for Inelastic Electromagnetic Interactions of Heavy Ions are both calculable and have been measured in the first RHIC running period.
The crabbing of an incident photonbeam from a laser, and the electron beam with which it interacts at the conversion point, is shown to have the same efficiency as in head-on Compton scattering, but with the advantages of a crossing geometry. The resulting #gamma#-ray beam is also crabbed, which allows for a crossing collision point, while maintaining the luminosity at the same value it would have in a head-on collision.
The crabbing of an incident photonbeam from a laser, and the electron beam with which it interacts at the conversion point, is shown to have the same efficiency as in head-on Compton scattering, but with the advantages of a crossing geometry. The resulting {gamma}-ray beam is also crabbed, which allows for a crossing collision point, while maintaining the luminosity at the same value it would have in a head-on collision. ((orig.)).
The crabbing of an incident photonbeam from a laser, and the electron beam with which it interacts at the conversion point, is shown to have the same efficiency as in head-on Compton scattering, but with the advantages of a crossing geometry. The resulting #gamma#-ray beam is also crabbed, which allows for a crossing collision point, while maintaining the luminosity at the same value it would have in a head-on collision. ((orig.)).
We present our plans for a Monte-Carlo code simulating all possible combinations of (electromagnetic) interactions between colliding electron, positron, and both high-energy and laser photonbeams, based on the ABEL code for beam-beam interaction. The implementation and first results for the laser-e{sup -} interaction are described. ((orig.)).
We present our plans for a Monte-Carlo code simulating all possible combinations of (electromagnetic) interactions between colliding electron, positron, and both high-energy and laser photonbeams, based, on the ABEL code for beam-beam interaction. The implementation and first results for the laser-e"- interaction are described.
The location of defective LMFBR fuel pins by the determination of gas tag isotopic ratios is discussed. The application of this method to the FFTF Reactor briefly described.
Objectives:The efficacy of user-defined subject tagging and software-generated subject tagging for describing and organizing cancer blog contents was explored.Methods:The...Full Text Available
For a given linac design, the dosimetric characteristics of a photonbeam are determined uniquely by the energy and radial distributions of the electron beam striking the x-ray target. However, in the usual commissioning of a beam from measured data, a large number of variables can be independently tuned, making it difficult to derive a unique and self-consistent beam model. For example, the measured dosimetric penumbra in water may be attributed in various proportions to the lateral secondary electron range, the focal spot size and the transmission through the tips of a non-divergent collimator; the head-scatter component in the tails of the transverse profiles may not be easy to resolve from phantom scatter and head leakage; and the head-scatter tails corresponding to a certain extra-focal source model may not agree self-consistently with in-air output factors measured on the ...
Bremsstrahlung emitted in the {alpha}+p reaction at 50 MeV/nucleon was studied using a 200 MeV {alpha}-particle beam and a liquid hydrogen target. Double-differential photon cross sections were measured over a wide range of angles and energies. Coherent bremsstrahlung was found to be strong for all photon energies. The cross section is enhanced at the highest photon energies and is characteristic of direct capture to the unbound {sup 5}Li ground and first excited state. With direct capture as a limiting case of coherent bremsstrahlung a consistent reaction picture can be obtained.
Calculations of dose per monitor unit (D∕MU) are required in addition to measurements to increase patient safety in the clinical practice of proton radiotherapy. As in conventional photon and...Full Text Available
A brief overview, from an experimentalist`s point of view, of the possibilities and difficulties involved in building a photon-photon collider using beams produced in Compton backscattering from a linear e{sup +}e{sup -} or e{sup -}e{sup -}collider. Some hindsight is included from the successful March 1994 Berkeley workshop on gamma-gamma colliders. (author). 13 refs., 2 figs.
A brief overview, from an experimentalist's point of view, of the possibilities and difficulties involved in building a photon-photon collider using beams produced in Compton backscattering from a linear e"+e"- or e"-e"-collider. Some hindsight is included from the successful March 1994 Berkeley workshop on gamma-gamma colliders. (author). 13 refs., 2 figs.
Future linear colliders offer unique opportunities to study {gamma}{gamma}, {gamma}e interactions. Using the laser backscattering method one can obtain {gamma}{gamma}, {gamma}e colliding beams with energy and luminosity comparable to the electron-position luminosity or even higher. In this review physical principles of photon colliders are described and various problems, concerning the accelerator, laser, interaction region and luminosity are discussed. Some examples of physical processes are given. ((orig.)).
It seems to be very natural that whole program for constructing and exploring of linear colliders (including photon colliders as the substantial part) should be divided by stages according to the increasing beam energy. We discuss the main stages of this program and the set of physical problems for each stage photon colliders. ((orig.))
It seems to be very natural that whole program for constructing and exploring of linear colliders (including photon colliders as the substantial part) should be divided by stages according to the increasing beam energy. We discuss the main stages of this program and the set of physical problems for each stage photon colliders. ((orig.)).
In the present paper, a possible interaction region layout of the VLEPP based Photon Linear Collider (PLC) with ultimate luminosity is discussed. In order to remove spent electron beams, the crab-crossing scheme is used. The detector is protected from produced pairs and secondary particles by means of the detector magnetic field and a shielding mask. ((orig.)).
We investigate the chargino production process {gamma}{gamma} {yields} (W-tilde){sup +}(W-tilde){sup -} at high energy {gamma}{gamma} colliders in the framework of the minimal supersymmetric standard model (MSSM). Here the high energy {gamma} beams are obtained by the backward Compton scattering of the laser flush by the electron in the basic linear TeV ee colliders. We consider the polarization of the laser photons as well as the electron beams. Appropriate beam polarization could be effective to enhance the cross section to for us extract the signal from the dominant background {gamma}{gamma} {yields} W{sup +}W{sup -}. (author).
We investigate the chargino production process #gamma##gamma# #-># (W-tilde)"+(W-tilde)"- at high energy #gamma##gamma# colliders in the framework of the minimal supersymmetric standard model (MSSM). Here the high energy #gamma# beams are obtained by the backward Compton scattering of the laser flush by the electron in the basic linear TeV ee colliders. We consider the polarization of the laser photons as well as the electron beams. Appropriate beam polarization could be effective to enhance the cross section to for us extract the signal from the dominant background #gamma##gamma# #-># W"+W"-. (author).
Physical processes in the region of laser conversion for the next Linear Colliders (NLC) are discussed. The main goal of this conversion is to obtain high-energy intense #gamma# beams for #gamma#e and #gamma##gamma# colliders. This conversion has important by-products: (i) one can observe here effect of nonlinear QED (in a strong external field)-production of e"+e"- pairs by a high-energy photon and emission of very high-energy photons by an electron; (ii) one can produce and observe here the invisible axion in colliding #gamma#_0e beams. The NQED effects also result in variation of the spectra of high-energy photons and an additional background. 12 refs., 12 figs., 1 tab.
Anti-TAG-72 monoclonal antibodies target the tumor-associated glycoprotein (TAG)-72 in various solid tumors. This study evaluated the use of anti-TAG-72 monoclonal antibodies, both murine CC49...Full Text Available
Laser-induced phase-separation polymerization of a porous acrylate polymer is used for in-situ fabrication of dialysis membranes inside glass microchannels. A shaped 355 nm laser beam is used to produce a porous polymer membrane with a thickness of about 15 .mu.m, which bonds to the glass microchannel and forms a semi-permeable membrane. Differential permeation through a membrane formed with pentaerythritol triacrylate was observed and quantified by comparing the response of the membrane to fluorescein and fluorescently tagging 200 nm latex microspheres. Differential permeation was observed and quantified by comparing the response to rhodamine 560 and lactalbumin protein in a membrane formed with SPE-methylene bisacrylamide. The porous membranes illustrate the capability for the present technique to integrate sample cleanup into chip-based analysis systems.
Typical beam lines are comprised of an assembly of vacuum valves and shutters referred to as a ''front end'', optical elements to monochromatize, focus and split the photonbeam, and an experimental area where a target sample is placed into the photonbeam and data from the interaction is detected and recorded. Windows are used to separate sections of beam lines that are not compatible with storage ring ultra high vacuum. Some experimental beam lines share a common vacuum with storage rings. Sections of beam lines are only allowed to vent up to atmospheric pressure using pure nitrogen gas after a vacuum barrier is established to protect ring vacuum. The front end may only be bled up when there is no current in the machine. This is especially true on the VUV storage ring where for most ...
We propose a scheme with potential experimental realization to generate 'polarization' entanglement between two atomic ensembles and show one of the applications - a novel secure communication allowing asymptotically key distribution and quasisecure direct communication. The scheme involves laser manipulation of atomic ensembles, adjustable quarter- and half-wave plates, beam splitters, polarizing beam splitters and single-photon detectors, and well fits the status of the current experimental technology.
A brilliant X ray source is proposed for lithography instruments with use of a multi-mirror system. The inverse Compton scattering between the stored electron beam in the storage ring and the stored photonbeam in the multi-mirror system, is applied for the X-ray generation. (author)
It is proposed to measure the spot sizes and polarization of #gamma# beams of future #gamma#e and #gamma##gamma# colliders detecting e"+e"- pairs produced as a result of interaction of high energy #gamma# quanta with density modulated and not modulated laser photons. The quantum electrodynamics cross sections, necessary numerical results as well as a short comparison of the proposed method with some other methods are given. (orig.).
The performance of a convolution/superposition based treatment planning system depends on the ability of the dose calculation algorithm to accurately account for physical interactions taking place in the tissue, key components of the linac head and on the accuracy of the photonbeam model. Generally the user has little or no control over the performance of the dose calculation algorithm but is responsible for the accuracy of the beam model within the constraints imposed by the system. This study explores the dosimetric impact of limitations in photonbeam modeling accuracy on complex 3D clinical treatment plans. A total of 70 photonbeam models was created in the Pinnacle(TM) treatment planning system. Two of the models served as references for 6 MV and 15 MV beams, while the rest were created by perturbing the reference ...
Electron beams as a source of directed energy are under study at the Lawrence Livermore National Laboratory (LLNL). An intense 10-kA, 50-MeV, 50-ns full-width half-maximum, pulsed electron beam is generated by the prototype Advanced Test Accelerator (ATA) at the Laboratory's Site 300. Whenever the electron beam is stopped in materials, intense radiation is generated. Estimates based on available data in the literature show that for materials such as lead, photon radiation (x ray, gamma, bremsstrahlung) levels can be as large as 10"4 roentgens per pulse at 1 m in the zero-degree direction (i.e., the electron-beam direction). Neutrons, which are emitted isotropically, are produced at a level of 10"1"3 n/m"2 per pulse. Depending upon the number of pulses and the shielding geometry, the accumulated dose is potentially lethal to personnel and potentially damaging to instrumentation that ...
Thermal neutron beam from the TNRF of JRR-3M was utilized for detection of mice lung cancer in vivo. Both the static and real-time neutron imaging were tried. Very strong thermal neutron beam is necessary to detect lung cancers because small changes are hidden by the very large attenuation of thermal neutron beam by the hydrogens in the tissues. The detection was successfully performed. Especially, the Super Eye of Hamamatsu Photonics contributed very effectively. Bone marrows and cartilages were also shown clearly. If an efficient and compact neutron source will become available in future, this method will grow up as a powerful tool for biomedical application. (author).
The convolution/superposition algorithm for computing dose from photonbeams in radiation therapy planning requires knowledge of the energy spectrum. The algorithm can compute the dose for a polyenergetic beam as the weighted sum of the individual dose contributions from monoenergetic beams. In this study we exploit interface effects apparent in the dose distributions to discriminate among spectra of high energy photonbeams. We have studied the sensitivity of the depth dose distribution to the energy components using a hypothetical beam for various field sizes and depths in water and water-lung-water media. Six theoretical spectra were simulated. We compared depth dose data from these spectra using three quantitative measures which are inherently free of normalization ambiguities: for homogeneous water, the ratio D_2_0/D_1_0 and a ...
The possible parameters of a photon linear collider at its ultimate luminosity, based on the VLEPP physics and technology V.E. Balakin et al., Proc. 6th Nat. Conf. on Accelerators, Dubna, 1978; V.E. Balakin, Proc. 4th Int. Workshop on Next Generation Linear Colliders, Garmisch, 1992, are presented. At a photon energy of 100x100 GeV the maximum achievable luminosity is about 1x10{sup 36} cm{sup -2} s{sup -1}. Beam parameters, luminosity characteristics, and ways to reduce the background are considered as well. ((orig.)).
We discuss various reactions at future e"+e"- and #gamma##gamma# colliders involving real (beamstrahlung or backscattered laser) or quasi-real (bremsstrahlung) photons in the initial state and hadrons in the final state. The production of two central jets with large transverse momentum p_T is described in some detail; we give distributions for the rapidity and p_T of the jets as well as the di-jet invariant mass, and discuss the relative importance of various initial state configurations and the uncertainties that arise from the at present rather poor knowledge of the parton content of the photon. We also present results for 'mono-jet' production where one jet goes down a beam pipe, for the production of charm, bottom and top quarks, and for single production of W and Z bosons. Where appropriate, the two-photon processes are compared with annihilation reactions leading to similar final states. We also ...
This Final Report documents the research accomplishments achieved in the first phase of operations of a new Advanced Photon Source beam line (7-ID MHATT-CAT) dedicated to real-time x-ray studies. The period covered by this report covers the establishment of a world-class facility for time-dependent x-ray studies of materials. During this period many new and innovative research programs were initiated at Sector 7 with support of this grant, most notably using a combination of ultrafast lasers and pulsed synchrotron radiation. This work initiated a new frontier of materials research: namely, the study of the dynamics of materials under extreme conditions of high intensity impulsive laser irradiation.
In the beam pipe of the positron damping ring of the Next Linear Collider, electrons will be created by beam interaction with the surrounding vacuum chamber wall and give rise to an electron cloud. Several solutions are possible for avoiding the electron cloud, without changing the bunch structure or the diameter of the vacuum chamber. Some of the currently available solutions for preventing this spurious electron load include reducing residual gas ionization by the beam, minimizing beamphoton-induced electron production, and lowering the secondary electron yield (SEY) of the chamber wall. We will report on recent SEY measurements performed at SLAC on TiN coatings and TiZrV non-evaporable getter thin films.
The basic relationships of the convolution/superposition dose calculation technique are reviewed, and a modelling technique that can be used for obtaining a satisfactory beam model for a commercially available convolution/superposition-based treatment planning system is described. A fluence energy spectrum for a Co-60 treatment machine obtained from a Monte Carlo simulation was used for modelling the fluence spectrum for a Rokus M machine. In order to achieve this model we measured the depth dose distribution and the dose profiles with a Wellhofer dosimetry system. The primary fluence was iteratively modelled by comparing the computed depth dose curves and beam profiles with the depth dose curves and crossbeam profiles measured in a water phantom. The objective of beam modelling is to build a model of the primary fluence that the patient is exposed to, which can then be used for the calculation of the dose deposited in the ...
Adjustment of the rf phase in a linear accelerator is crucial for maintaining optimal performance. If phasing is incorrect, the beam will in general have an energy error and increased energy spread. While an energy error can be readily detected and corrected using position readings from beam position monitors at dispersion locations, this is not helpful for correcting energy spread in a system with many possible phase errors. Uncorrected energy spread results in poor capture efficiency in downstream accelerators, such as the Advanced Photon Source's (APS's) particle accumulator ring (PAR) or booster synchrotron. To address this issue, APS has implemented beam-to-rf phase detectors in the linac, along with software for automatic correction of phase errors. We discuss the design, implementation, and performance of these detectors and how they improved APS top-up operations.
Radiotherapy with high-energy carbon ion beams can be more advantageous compared to photons because of better physical dose distribution and higher biological efficiency in tumour cell sterilization. Despite enhanced normal tissue sparing, damage incurred by normal cells at the beam entrance is unavoidable and may affect the progeny of surviving cells in the form of inheritable cytogenetic alterations. Furthermore, the quality of the beam along the Bragg curve is modified by nuclear fragmentation of projectile and target nuclei in the body. We present an experimental approach based on the use of a polymethylmethacrylate (PMMA) phantom that allows the simultaneous exposure to a particle beam of several biological samples positioned at various depths along the beam path. The device was used to measure the biological effectiveness of a 60 MeV/amu carbon-ion ...
Ion Beam Induced Luminescence (IBIL) and Ion Beam Induced Charge Collection (IBICC) have been applied in the study of the luminescence emission efficiency and investigation of the homogeneity of the luminescence emission in phosphors. The IBIL imaging was performed by using sharply focused ion beams or broad/partially-focused ion beams. The luminescence emission homogeneity in samples was examined to reveal possible distributed crystal-defects that may lead to the inhomogeneity of the luminescence emission in samples.The purpose of the study is to search for suitable luminescent thin films that have high homogeneity of luminescence emission, large IBIL efficiency under heavy ion excitation, and can be placed as a thin layer on the top of microelectronic devices to be analyzed with Ion Photon Emission Microscopy (IPEM). The emission yield was found to be low for organic materials, ...
Polarization measurements in the X-ray and gamma-ray energy range can provide crucial information on massive compact objects such as black holes and neutron stars. The Polarized Gamma-ray Observer (PoGO) is a new balloon-borne instrument designed to measure polarization from astrophysical objects in the 30-100 keV range, under development by an international collaboration with members from United States, Japan, Sweden and France. To examine PoGO's capability, a beam test of a simplified prototype detector array was conducted at the Argonne National Laboratory Advanced Photon Source. The detector array consisted of seven plastic scintillators, and was irradiated by polarized photonbeams at 60, 73, and 83 keV. The data showed a clear polarization signal, with a measured modulation factor of $0.42 \\pm 0.01$. This was successfully reproduced at the 10% level by the computer simulation package Geant4 after ...
Monte Carlo simulation of beam modifiers such as physical wedges and compensating filters has been performed with a rectilinear voxel geometry module. A modified version of the EGS4/DOSXYZ code has been developed for this purpose. The new implementations have been validated against the BEAM Monte Carlo code using its standard component modules (CMs) in several geometrical conditions. No significant disagreements were found within the statistical errors of 0.5% for photons and 2% for electrons. The clinical applicability and flexibility of the new version of the code has been assessed through an extensive verification versus dosimetric data. Both Varian multi-leaf collimator (MLC) wedges and standard wedges have been simulated and compared against experiments for 6 MV photonbeams and different field sizes. Good agreement was found between calculated and measured depth doses and ...
An overview of particle and photonbeam bunch length measurements is presented in the context of free-electron laser (FEL) challenges. Particle-beam peak current is a critical factor in obtaining adequate FEL gain for both oscillators and self-amplified spontaneous emission (SASE) devices. Since measurement of charge is a standard measurement, the bunch length becomes the key issue for ultrashort bunches. Both time-domain and frequency-domain techniques are presented in the context of using electromagnetic radiation over eight orders of magnitude in wavelength. In addition, the measurement of microbunching in a micropulse is addressed.
The convolution/superposition calculations for radiotherapy dose distributions are traditionally performed by convolving polyenergetic energy deposition kernels with TERMA (total energy released per unit mass) precomputed in each voxel of the irradiated phantom. We propose an alternative method in which the TERMA calculation is replaced by random sampling of photon energy, direction and interaction point. Then, a direction is randomly sampled from the angular distribution of the monoenergetic kernel corresponding to the photon energy. The kernel ray is propagated across the phantom, and energy is deposited in each voxel traversed. An important advantage of the explicit sampling of energy is that spectral changes with depth are automatically accounted for. No spectral or kernel hardening corrections are needed. Furthermore, the continuous sampling of photon direction allows us to model sharp changes in fluence, such as those ...
The current primary standards at NPL for the measurement of absorbed dose to water in high energy photon and electron beams are graphite calorimeters. However, the quantity of interest in radiation dosimetry is absorbed dose to water. Therefore, a new absorbed dose to water standard based on water calorimetry has been developed for use in high energy photon and electron beams. The calorimeter operates at 4 deg C, with temperature control being provided by liquid cooling. The sealed glass inner vessel of the calorimeter was designed to minimise the effect of non-water materials on the measurement of absorbed dose. The temperature sensing thermistor probes were designed and constructed so that glass is the only material in contact with high purity water inside the vessel. Initial measurements of absorbed dose to water made in 6, 10, and 19 MV photons, and 16 MeV electrons agreed, ...
Increasingly, business projects are ephemeral. New Business Intelligence tools must support ad-lib data sources and quick perusal. Meanwhile, tag clouds are a popular community-driven visualization technique. Hence, we investigate tag-cloud views with support for OLAP operations such as roll-ups, slices, dices, clustering, and drill-downs. As a case study, we implemented an application where users can upload data and immediately navigate through its ad hoc dimensions. To support social networking, views can be easily shared and embedded in other Web sites. Algorithmically, our tag-cloud views are approximate range top-k queries over spontaneous data cubes. We present experimental evidence that iceberg cuboids provide adequate online approximations. We benchmark several browser-oblivious tag-cloud layout optimizations.
To gain insight into the changes in the transcriptome of soybean roots during soybean cyst nematode (SCN) infection, we conducted genome-wide gene expression profiling using serial analysis of gene expression (SAGE) combined with Solexa sequencing. More than 3 million tags were generated from the SCN-infected and uninfected roots, and 366941 and 314591 clean UniTags were obtained from SCN-infected and uninfected samples, respectively. In the SCN-infected sample, 48249 UniTags represented 18114 reference genes. In the uninfected control, 46290 UniTags represented 19323 reference genes. Comparison of tag frequencies identified 1405 genes that were expressed at greater levels in SCN-infected roots than in uninfected roots, and 1191 genes that were expressed at lower levels. Quantitative real-...
Increasingly, business projects are ephemeral. New Business Intelligence tools must support ad-lib data sources and quick perusal. Meanwhile, tag clouds are a popular community-driven visualization technique. Hence, we investigate tag-cloud views with support for OLAP operations such as roll-ups, slices, dices, clustering, and drill-downs. As a case study, we implemented an application where users can upload data and immediately navigate through its ad hoc dimensions. To support social networking, views can be easily shared and embedded in other Web sites. Algorithmically, our tag-cloud views are approximate range top-k queries over spontaneous data cubes. We present experimental evidence that iceberg cuboids provide adequate online approximations. We benchmark several browser-oblivious tag-cloud layout optimizations.
An energy frontier or QCD Explorer ep and collider can be realized by colliding high-energy photons generated by Compton backscattered off a CLIC electron beam, at either 75 GeV or 1.5 TeV, with protons or ions stored in the LHC. In this study we discuss a performance optimization of this type of collider by tailoring the parameters of both CLIC and LHC. An estimate of the ultimately achievable luminosity is given.
Dose calculations for radiation arc therapy are traditionally performed by approximating continuous delivery arcs with multiple static beams. For 3D conformal arc treatments, the shape and weight variation per degree is usually small enough to allow arcs to be approximated by static beams separated by 5"0-10"0. But with intensity-modulated arc therapy (IMAT), the variation in shape and dose per degree can be large enough to require a finer angular spacing. With the increase in the number of beams, a deterministic dose calculation method, such as collapsed-cone convolution/superposition, will require proportionally longer computational times, which may not be practical clinically. We propose to use a homegrown Monte Carlo kernel-superposition technique (MCKS) to compute doses for rotational delivery. The IMAT plans were generated with 36 static beams, which were subsequently interpolated into finer ...
The proton beam has a unique advantage over the electron and photonbeams in that it can give very high radiation dose to the tumor volume, while effectively sparing the neighboring healthy tissue and organs. For the clinical application of the proton beam, it is very important to confirm the location of the proton beam in the patient, preferentially during the treatment. It has been suggested that the range of the proton beam in the patient can be determined by measuring prompt gammas from the proton beam passage. Recently, a prototype prompt-gamma scanning system has been constructed and tested using experimental and therapeutic proton beams. The measurement results for the proton beams of 70 . 230 MeV showed that a clear correlation exists between the distribution of the prompt gammas and the ...
Beams may be viewed as directed and focussed flow of energy and information, carried by particles and electromagnetic radiation fields (ie, photons). Often, they interact with each other (eg, in high energy colliders) or with other forms of matter (eg, in fixed targets, sychrotron radiation, neutron scattering, laser chemistry/physics, medical therapy, etc.). The whole art and science of beams revolve around the fundamental quest for, and ultimate implementation of, mechanisms of production, storage, control and observation of beams -- always directed towards studies of the basic structures and processes of the natural world and various practical applications. Tremendous progress has been made in all aspects of beam physics and technology in the last decades -- nonlinear dynamics, superconducting magnets and rf cavities, beam instrumentation and control, novel ...
Purpose/Objective: With the advent of computed tomography and magnetic resonance imaging, the three dimensional representation of the patient anatomy has become an invaluable resource for better diagnosis and delineation of the target volume and sensitive structures in radiation therapy. Although the therapeutic linear accelerator industry has made available highly sophisticated equipment, the aggressiveness in dose prescription and delivery has to be complimented by accurate dose computation methods. We have adopted a convolution/superposition algorithm for the calculation of absolute dose that fully accounts for the external shape and internal structure of the patient for photon treatment radiotherapy. In this paper, we will discuss the principles of the convolution algorithm and we will show how the computed dose compares to clinically relevant treatment techniques. Materials and Methods: A computer controlled data acquisition system and a water tank where used ...
The desire to study negative ion structure and negative ion-photon interactions has spurred the development of ion sources for use in research and industry. The many different types of negative ion sources available today differ in their characteristics and abilities to produce anions of various species. Thus the importance of choosing the correct type of negative ion source for a particular research or industrial application is clear. In this study, the results of an investigation on the production of beams composed of negatively-charged rare-earth ions from a cylindrical-cathode-geometry, cesium-sputter-type negative ion source are presented. Beams of atomic anions have been observed for most of the first-row rare-earth elements, with typical currents ranging from hundreds of picoamps to several nanoamps.
Subcutaneous involvement frequently occurs in maxillary sinus carcinoma. Radical resection does not include removal of the skin at risk. In standard postoperative wedge-pair treatment plans, the surface dose is dependent upon beam weighting, beam energy, and patient contour. Thermoluminescent dosimetry (TLD) measurements were performed to evaluate the surface dose of patients undergoing postoperative irradiation of maxillary sinus carcinoma following primary resection. When 60 Gy was delivered to isocenter with a 45 degrees wedge pair and 6 MV photons with 1 cm bolus, the subcutaneous tissues at risk received {approximately} 30 Gy. Based upon presented TLD measurements, supplemental electron beam therapy to the subcutaneous tissues if primarily involved should be considered.
Between 1984 and 1988, seven women with breast cancer were treated with intraoperative electron beam therapy (IOEBT). All patients were Caucasian. Patient age ranged from 37 to 62 (median 53) years. Histopathology was infiltrating duct carcinoma (6/7) or medullary carcinoma (1/7). Four tumors were staged T1 N0 MO, one T1 N1 MO, one T2 N1 MO, and one lesion was recurrent. At the time of primary lumpectomy or axillary node dissection, a dose of 10 or 15 Gy IOEBT was administered to the tumor bed with 6 or 9 MeV electrons through the lumpectomy wound. All patients received 45 or 50 Gy over five to six weeks with 6 MV photons to the breast and, in four patients, to the regional nodes. Three patients received adjuvant chemotherapy and tamoxifen. No post-operative complications were observed. All patients are alive as of August, 1989, with no evidence of recurrent disease. Excellent cosmesis is the rule. Clinical and technical aspects of treatment ...
A future e"-e"+ (electron-positron) linear collider can be configured with perhaps minimal modification to serve as an #gamma#-#gamma# (gamma-gamma) or a e"--#gamma# collider. This is accomplished by Compton-backscattering low energy photons (from a laser source) off of the high-energy electron beams prior to the crossing of the electron beams. However, to be competitive with the e"-e"+ configuration, the luminosity cannot be compromised in the process. This requires that the laser source deliver a sufficient number of photons per pulse with a pulse format and rate matching that of the electron beams. As it turns out, this requires an average optical power of 5 to 15 kW from the laser which is beyond the current state of the art. In this paper, the authors address how to generate the required pulse format and how the high average power requirement can be met with conventional laser ...
A future e{sup -}-e{sup +} (electron-positron) linear collider can be configured with perhaps minimal modification to serve as an {gamma}-{gamma} (gamma-gamma) or a e{sup -}-{gamma} collider. This is accomplished by Compton-backscattering low energy photons (from a laser source) off of the high-energy electron beams prior to the crossing of the electron beams. However, to be competitive with the e{sup -}-e{sup +} configuration, the luminosity cannot be compromised in the process. This requires that the laser source deliver a sufficient number of photons per pulse with a pulse format and rate matching that of the electron beams. As it turns out, this requires an average optical power of 5-15 kW from the laser which is beyond the current state of the art. In this paper, we address how to generate the required pulse format and how the high average power requirement can be met with ...
A future e{sup {minus}}e{sup +} (electron-positron) linear collider can be configured with perhaps minimal modification to serve as an {gamma}-{gamma} (gamma-gamma) or a e{sup {minus}}-{gamma} collider. This is accomplished by Compton-backscattering low energy photons (from a laser source) off of the high-energy electron beams prior to the crossing of the electron beams. However, to be competitive with the e{sup {minus}}e{sup +} configuration, the luminosity cannot be compromised in the process. This requires that the laser source deliver a sufficient number of photons per pulse with a pulse format and rate matching that of the electron beams. As it turns out, this requires an average optical power of 5 to 15 kW from the laser which is beyond the current state of the art. In this paper, the authors address how to generate the required pulse format and how the high average power ...
A real-time orbit feedback system has been implemented at the Advanced Photon Source in order to meet the stringent orbit stability requirements. The system reduces global orbit motion below 30Hz by a factor of four to below 5{micro}m rms horizontally and 2{micro}m rms vertically. This paper focuses on dynamic orbit stability and describes the all-digital orbit feedback system that has been implemented at the APS. Implementation of the global orbit feedback system is described and its latest performance is presented. Ultimately, the system will provide local feedback at each x-ray source point using installed photon BPMs to measure x-ray beam position and angle directly. Technical challenges associated with local feedback and with dynamics of the associated corrector magnets are described. The unique diagnostic capabilities provided by the APS system are discussed with reference to their use in identifying sources of the ...
During the last few decades, accuracy in photon and electron radiotherapy has increased substantially. This is partly due to enhanced linear accelerator technology, providing more flexibility in field definition (e.g. the usage of computer-controlled dynamic multileaf collimators), which led to intensity modulated radiotherapy (IMRT). Important improvements have also been made in the treatment planning process, more specifically in the dose calculations. Originally, dose calculations relied heavily on analytic, semi-analytic and empirical algorithms. The more accurate convolution/superposition codes use pre-calculated Monte Carlo dose "kernels" partly accounting for tissue density heterogeneities. It is generally recognized that the Monte Carlo method is able to increase accuracy even furt...
A number of difficult technical challenges need to be solved in the fields of accelerator and free-electron laser (FEL) technologies in order to build an X-ray FEL. One of the tasks well suited to the Advanced Photon Source Low Energy Undulator Test Line (LEUTL) is to take the intermediate step of solving some of the problems of single-pass FEL operation in the ultraviolet range. The existing Advanced Photon Source (APS) linac, in addition to its role of supply positrons for the APS storage ring, will also be used to generate the particle beam for the LEUTL. Here, the design of the magnetic system for the high gain soft x-ray free electron laser is described.
The subject of quantum optics has undergone considerable development in the last twenty-five years. Spurred by the invention of the laser, the theoretical understanding of the coherence and statistical properties of optical beams has now attained a stage of maturity where it is possible to treat different kinds of light sources. Over approximately the latter half of this period of development in quantum optics, the free-electron laser (FEL) has been developed to the point where it is now regarded as a tunable light source of considerable versatility, with prospects of producing radiation over a wide range of wavelengths at large levels of power. Since the basic mechanism for radiation gain in an FEL can be understood in classical terms, much of the literature on the subject does not need to venture outside the domain of classical physics. However, it is natural that the coherence and statistical properties of photonbeams ...
The purpose of this work was to develop and evaluate a method of locating breached fuel within the Fast Flux Test Facility (FFTF) reactor based on the relative response of the delayed neutron monitors (DNM) located on each of the three primary sodium cooling loops. The primary method of location is the use of tag gas containing unique ratios of the noble gases xenon and krypton. Although the tag gas system works quite well, it is relatively expensive because of the costs of preparing and loading the gas into each fuel pin. Triangulation of DNM signals could potentially decrease tag gas costs while maintaining overall location reliability.
For 12C 9Be interactions at a kinetic beam energy of 3.2 GeV per nucleon, the spectra of photons at laboratory angles in the range 55o-73o were measured off the kinematical region available to the interaction of single nucleons within colliding nuclei. The use of a fast trigger for selecting events involving the production of high-transverse-momentum photons made it possible to measure spectra off the kinematical boundary of four-nucleon interaction. It is shown that the proposed procedure is adequate to the problem of searches for and investigation of flucton-flucton interaction. In the kinematical region where flucton-flucton interaction can manifest itself, the cross sections in question are on the same order of magnitude as respective model predictions. In order to draw definitive conclusions on the role of flucton-flucton interaction, it is highly desirable to extend the angular range of the measurements toward smaller ...
The mass generation in the Standard Model of Particles Physics relies on a spontaneous symmetry breaking mechanism. Its implementation is recalled, along with its constraints, both theoretical (Naturalness, Stability, Triviality, Unitarity) and experimental (limits of direct and indirect searches, prospects). Calculation techniques for observables evaluation in Perturbative Field Theory are described, particularly Helicity Amplitude method, which is given in details: fermions and vector bosons, massless and massive. Monte-Carlo integration, and structure functions approximations (which allows non-perturbative calculations) are also detailed. With these tools, a process giving to Physics beyond the Standard Model is studied: it leads to an experimental prediction for the LEP collision ring, taking the classical background into account. Technical aspects of a future photon linear collider are reviewed. The production of heavy vector bosons, either the classical Z for ...
Mar 15, 2010... Boulder have demonstrated that a five-nucleotide-long ribozyme can ... animals anoxia anoxia biomarker permian cambrian terrestrial ...
To establish the optimum barium-based reduced-laxative tagging regimen prior to CT colonography (CTC). Ninety-five subjects underwent reduced-laxative (13 g senna/18 g magnesium citrate) CTC prior to same-day colonoscopy and were randomised to one of four tagging regimens using 20 ml 40%w/v barium sulphate: regimen A: four doses, B: three doses, C: three doses plus 220 ml 2.1% barium sulphate, or D: three doses plus 15 ml diatriazoate megluamine. Patient experience was assessed immediately after CTC and 1 week later. Two radiologists graded residual stool (1: none/scattered to 4: >50% circumference) and tagging efficacy for stool (1: untagged to 5: 100% tagged) and fluid (1: untagged, 2: layered, 3: tagged), noting the HU of tagged fluid. Preparation was good (76-94% segments graded 1), although best for regimen D (P = 0.02). Across all regimens, stool ...
Portal verification images were generated from the photon contamination in electron beams produced by a linear accelerator during treatment of patients receiving high-energy electron radiation therapy (8-14 MeV). An experimental storage phosphor system was used to record the images and display them on laser-printed film. Images were obtained from four or more treatment fractions from 21 cases of head and neck cancer. Precision in field placement was estimated by determining the position of a selected anatomic landmark relative to the center of the field for each series of images. The average standard deviation in the field-position measurements was 3.8 mm. Several procedural problems were also detected and corrected after review of the verification images. The results indicate that the emphasis placed on monitoring and control of field-positioning error in high-energy electron treatments should be similar to the emphasis placed on this aspect ...
When a highly collimated beam of particles is aimed along the atomic rows of an aligned single crystal, the averaging effect of high speed motion results, to the lowest order of approximation, in crystal electric fields which are transverse to the atomic rows. The enormous magnitude of the crystal transverse electric fields is unsurpassed by any other known earth-bound macroscopic sources. For example, the field strengths along the <100> axis of tungsten at 77 K approach 9{center dot}10{sup 13}V/m. Thus quantum electrodynamic (QED) processes in strong fields which are thought to occur only in the extra-terrestrial environment can now be investigated in the laboratory. Here we review the results of measurements performed at the SPS facility in CERN using highly collimated beams of electrons, positrons and photons in the 20-200 GeV range, and germanium crystals cooled to 77 K with thicknesses ranging from 0.07 mm to ...
Simulations and experiments have been carried out to explore using a plastic scintillator as a dosimetry probe in the vicinity of a pulsed bremsstrahlung source in the range 4 to 20 MeV. Taking advantage of the tissue-equivalent properties of this detector in conjunction with the use of a fast digital signal processor near real-time dosimetry was shown to be possible. The importance of accounting for a broad energy electron beam in bremsstrahlung production, and photon scattering and build-up, in correctly interpreting dosimetry results at long stand-off distances is highlighted by comparing real world experiments with ideal geometry simulations. Close agreement was found between absorbed energy calculations based upon spectroscopic techniques and calculations based upon signal integration, showing a ratio between 10 MeV absorbed dose to 12 MeV absorbed dose of 0.66 at a distance of 91.4 m from the accelerator. This is compared with an ...
Single photon emission computed tomography (SPECT) of lung perfusions permits to map functioning lung parenchyma with higher sensitivity than CT. Delivering higher radiations doses it used to increase local control in lung carcinoma; this strategy is based on radiobiological and clinical studies. Lung parenchyma is a dose-limiting tissue in patients irradiated for lung cancer. Functional mapping based on SPECT and CT findings permits to design radiation beams such as to minimize irradiation of functioning lung.
Various particle-photon or beam-wave interactions are discussed. To be of use as intense radiation sources, it is necessary that these interactions produce coherent radiation. The free electron laser (FEL), developed on the basis of undulator radiation, is the result of many years of interaction between physics and technology. It has many features, such as continuous tunability over a wide wavelength range, excellent optical quality, high power and short pulse capability, and thus has many potential applications. FEL development in China and abroad are mentioned and the Beijing FEL presented to illustrate the physics and technology involved in an FEL project.
Most general tbW couplings were investigated in the process {gamma}{gamma} {yields} tt-bar {yields} l{sup {+-}}X for unpolarized photonbeams. The double angular and energy distribution of the lepton was calculated and an optimal-observable analysis on it was carried out for the SM tt-bar production mechanism. It was also shown that the leptonic angular distribution is insensitive to non-standard tbW vertex. That means that observation of non-standard effects indicates existence of some new physics in the production part.
Most general tbW couplings were investigated in the process #gamma##gamma# #-># tt-bar #-># l"#+-#X for unpolarized photonbeams. The double angular and energy distribution of the lepton was calculated and an optimal-observable analysis on it was carried out for the SM tt-bar production mechanism. It was also shown that the leptonic angular distribution is insensitive to non-standard tbW vertex. That means that observation of non-standard effects indicates existence of some new physics in the production part.
The local strain and texture in Al interconnect wires have been investigated using white and monochromatic x-ray microbeams on the MHATTCAT undulator beam line at the Advanced Photon Source. Intergrain and intragrain orientations were obtained with ~0.01 degree sensitivity using white beam measurements on wide Al pads (~100 Mu-m) and thin (2 Mu-m) Al wires. Orientation changes of up to 1 degree were found within individual grains of the (111) textured Al interconnects. Deviatoric strain measurements indicate small intragranular strain variations, but intergranular strain variations were found to be quite large.
Electrons may be used beneficially for spinal axis irradiation in medulloblastoma children to avoid some of the long-term sequelae induced by megavoltage photons. However, the attenuation by the intervening bone ought to be considered. Three-dimensional computer treatment planning with inhomogeneity correction for electron beams is not yet generally available, and alternate methods are needed to evaluate the attenuation by the complex bony structure of the spine. Here, we present our experimental data showing the alteration in the electron isodoses due to the intervening spinous processes. Film dosimetric measurements were made in the vertebral columns obtained from autopsies of a goat, a dog, and a child. Our results show that electron beam therapy for the spinal axis is a viable option.
The inverse Compton scattering between positron bunches and the Free Electron Laser (FEL) of the SuperAco storage ring generates a collimated and tunable gamma-ray beam. The use of the FEL instead of a conventional laser, automatically provides the transverse alignment and synchronisation of the electron and optical beams. The Super-ACO FEL is operated in the 300-430 nm range at 800 MeV with a high repetition rate (8 MHz) and an average transmitted power of 300 mW at 350 nm. High energy gamma rays of 35 MeV are produced with a rate of 1.5 10 7 photons/second and good monocromaticity (about 10%). Applications of the SuperAco FEL installation for diamond irradiation and biological studies are envisaged. (author)
A design of a compact free-electron laser (FEL), generating ultra-fast, high-peak flux, XUV pulses is presented. The FEL is driven by ahigh-current, 0.5 GeV electron beam from the Lawrence Berkeley National Laboratory (LBNL) laser-plasma accelerator, whose active acceleration length is only a few centimeters. The proposed ultra-fast source (~;;10 fs) would be intrinsically temporally synchronized to the drive laser pulse, enabling pump-probe studies in ultra-fast science. Owing to the high current (>10 kA) of the laser-plasma-accelerated electron beams, saturated output fluxes are potentially greater than 10^13 photons/pulse. Devices based both on self-amplified spontaneous emission and high-harmonic generated input seeds, to reduce undulator length and fluctuations, are considered.
The radioactive isotopes of lead are reviewed with respect to their choice for in vitro tracer studies. The #gamma#-photon energy and absence of particle emission in the decay of "2"0"3Pb makes it particularly suitable for these applications. Reaction yields of "2"0"3Pb using "2"0"3Tl targets and proton, deuteron, "3He and "4He beams are listed. Using the preferred reaction "2"0"3Tl (d, 2n)"2"0"3Pb with a 15 MeV deuteron beam, yields of about 75 #mu#Ci #mu#Ahr"-"1, after chemical separation, are reported. Details of target design and chemical separation are given. (U.K.).
Many thermoluminescent materials has been developed and used for photon personal dosimetry but no one has all desired characteristics alone. These characteristics include robustness, high sensitivity, energy photon independence, large range of photon energy detection, good reproducibility, small fading and simple glow curve with peaks above 150 deg C. Calcium Sulfate Dysprosium doped (CaSO{sub 4}:Dy) phosphor Thermoluminescent Dosimeter (TLD) has been used by many laboratories, mainly in Brazil and India. Another interesting phosphor is Calcium Fluoride (CaF{sub 2}). These phosphor advantages begin to be more required and its disadvantages have became more apparent, in a global market more and more competitive. These phosphors are used in environmental and area monitoring, once they present more sensibility than other phosphors, like LiF:Mg. Theirs mainly disadvantage is a strong energetic dependence response, which must be ...
A new three-dimensional treatment planning system (TPS) based on convolution/superposition algorithms (TMS-Radix from HELAX AB, Uppsala, Sweden) was recently installed at the University Hospital in Lund. The purpose of the present study was to design a quality assurance and acceptance testing programme to meet the specific characteristics of this convolution model. The model is based on parametrization of a non-measurable quantity - the polyenergetic pencil beam. However, the verification of the treatment planning model is still dependent on numerous comparisons of measured depth-doses and dose profiles. The test programme was divided in two basic parts: (i) model implementation and beam data consistency and (ii) model performance and limitations in special situations. The first part was scheduled for all photonbeam qualities available before they could be used for clinical treatment planning. The ...
The shell integrity near peak compression of spherical implosions using the 60-beam, 30-kJ UV OMEGA laser system [Opt. Commun. 133, 495 (1997)] has been measured. Hot core emission backlights a shell with a thin titanium-doped layer that is imaged at x-ray photon energies above and below the titanium K edge. The x-ray intensity ratio between the two images is related to perturbations in the cold, or absorbing, part of the shell. The measured cold-shell areal-density modulations, integrated over the time of peak compression, are of the order of 25% to 50% with nonuniformity spectra peaked at spatial wavelengths of 30 to 50 #mu#m and with the smallest detectable nonuniformity features extending down to spatial wavelengths of 12 to 15 #mu#m. Hot-shell areal-density modulations of the emitting part of the shell (inner edge) are of the order of 13% to 20%. The measured shell modulations are in agreement with the results of two-dimensional ...
The calculation of electronn beam dose using an algorithms similar to convolution/superposition methods for photonbeams [1,2,3,4] is explored. The distribution of dose deposited by a number of monoenergetic, point-monodirectional electron pencil beams is first determined using the Monte Carlo method [5,6]. These elementary distributions are combined to model distributions that would result from the spectrum of incident energies and angles [6,7] present in a clinical beam. These modified distributions are then stored for use as kernels in the dose calculation. In the case of a homogeneous phantom, the relative fluence distribution is convolved with the stored kernels to obtain thhe dose distributions in 3 dimensions. Since the kernels cannot be assumed to be spatially invariant in a heterogeneous water-like phantom, the dose deposited on paths from the interaction site to all the ...
Advanced modality of high-precision radiotherapy fulfilled by a composition of large numbers of small field beams called 'beamlets' can be achieved via nonuniform intensity fluencies. In case of radiation measurements and calculations with narrow high-energy photonbeams, however, an accurate two-dimensional dosimetry is a challenging task due to dosimetrically unfavorable phenomena such as dramatic changes of the dose at the field boundaries, dis-equilibrium of the electrons resulting from larger detector volume, and non-uniformity between the detector and the phantom materials. Meanwhile, with the advantages of high spatial resolution and wide range of absorbed doses, there is a growing demand of GAFCHROMICat..EBT film to confirm delivered dose distribution. Especially, the effects from the material differences between the phantom and the film can be minimized in the heterogeneous condition since the GAFCHROMICat..EBT ...
For understanding on basic radiation mechanism of the high-gain FEL based on SASE, the author presents electron-crystal interpretation of FEL radiation. In the electron-crystal, electrons are localized at regularly spaced multi-layers, which represents micro-bunching, whose spacing is equal to the radiation wavelength, and the multi-layers are perpendicular to beam axis, thus, diffracted wave creates Bragg's spots in forward and backward directions. Due to the Doppler's effect, frequency of the back-scattered wave is up-converted, generates forwardly focused X-ray. The Bragg's effect contributes focusing the X-ray beam into a spot, thus peak power becomes extremely higher by factor of typically 107. This is the FEL radiation. As well known, the total numbers of scattered photons in Bragg's spots is equal to the total elastic scattering photons from the atoms contained ...
The goal of this work is to present a systematic Monte Carlo validation study on the clinical implementation of the enhanced dynamic wedges (EDWs) into the Pinnacle"3 (Philips Medical Systems, Fitchburg, WI) treatment planning system (TPS) and QA procedures for patient plan verification treated with EDWs. Modeling of EDW beams in the Pinnacle"3 TPS, which employs a collapsed-cone convolution superposition (CCCS) dose model, was based on a combination of measured open-beam data and the 'Golden Segmented Treatment Table' (GSTT) provided by Varian for each photonbeam energy. To validate EDW models, dose profiles of 6 and 10 MV photonbeams from a Clinac 2100 C/D were measured in virtual water at depths from near-surface to 30 cm for a wide range of field sizes and wedge angles using the Profiler 2 (Sun Nuclear Corporation, Melbourne, FL) diode array system. The ...
For the Convolution, Superposition and Monte Carlo methods, energy spectrum data is an essential parameter. Especially, by using Monte Carlo method, if the adequate properties of electrons are set, complex energy spectrum data can be calculated by simple input. However, adjustment of the property of electrons incident on the target of linear accelerator is time-consuming procedure. To cover the difference of many accelerators, it is important how we obtain accurate energy spectrum by simple methods. Especially, the total accuracy of dose calculation depends on the agreement of measured and calculated percentage depth dose (PDD) and off-axis ratio (OAR). Thus, a simple method for the determination of the simulation parameters was considered. To reduce the adjustment procedure, we selected values of important three parameters, which were the mean energy of the input electron beam, the energy distribution of the input electron beam and the radial ...
We report on the single and double multiphoton ionization of ground state Sr atoms observed in an atomic beam experiment with laser pulses of {approx}5 ns duration, maximum intensity {approx}4 x 10{sup 11} W cm{sup -2} and within the 710-740 nm wavelength range. The Sr{sup +} spectrum consists of two strong lines originating from three-photon resonant four-photon ionization of bound states, a number of weak autoionizing resonances and a broad line due to four-photon excitation of the doubly excited 5p{sup 2} {sup 1}S{sub 0} state. The latter, along with a strong, broad and structured spectral feature, is also evident in the wavelength dependence of the doubly charged Sr{sup 2+} ion. A weakly evident but reproducible inflection point ('knee' structure) appears in the intensity dependence of the Sr{sup 2+} yield at the location of the 5p{sup 2} {sup 1}S{sub 0} resonance. A complementary ...
This work come along of the necessity to utilize an unique High-Energy Electron Linear Accelerator (10 MV) for radiant treatments which require higher doses in the surface levels of tissue. It is analyzed the interposition of acrylic degraders (spoilers) in the beam, especially for opposed and parallel fields in the cases of head and neck. It was analyzed the possible combinations of the following parameters: 1) Field sizes defined at isocenter (100 cm) 6 x 6 cm"2, 8 x 8 cm"2 and 10 x 10 cm"2 ; 2) Surface-spoiler distance (DSS) of 4, 7 and 10 cm; 3) Spoilers with different thickness 1.1 and 1.5 cm. It was observed a displacement of the maximum dose toward the surface, and an increase in the percentile doses in the build-up zone when the spoiler is nearing and/or increasing its thickness. It is verified that the use of spoilers, support the symmetry and plane of the beam inside of the clinically acceptable margins. When the results obtained are ...
Both x-ray and optical cone-beam CT (CBCT) scanners are limited by scattered photons that contaminate the primary images. Transparent radiochromic gels and plastics are anticipated to produce less scattering than polymerization gels and hence result in reconstructed dose distributions with greater contrast and dynamic range. Four methods of scatter measurement were investigated to quantify scatter fractions using an in-house optical CBCT scanner. The methods consisted of generating either 'coin' shadows or primary beamlets in transmission images. The four methods generated similar results of 10% scatter fractions in gel transmission images for this particular scanner configuration with both leuco crystal violet and carbon black micelle gels. The scatter contributions were distributed as 5% from micelle gel, 2% from Teflon wall, 2% from refractive index matching liquid and 1% other sources. Applying a uniform background ...
Measurements were carried out for calibration and performance testing of a set of 10 electronic personal dosimeters (EPDs) at the Secondary Standard Dosimetry Laboratory of Sudan. Calibrations were carried out at three X-ray beam qualities described in ISO standard 4037 in addition to 137Cs and 60Co gamma ray beams. The experimental was performed with EPDs mounted on ICRU Slab phantom. X-ray and ?-ray beams were characterized in terms of air kerma free-in-air which were converted to the known delivered personal dose equivalent, Hp(10) using appropriate the air kerma to personal dose equivalent conversion coefficients. Dosimeters tested showed excellent energy and angular response and relative error of indication within the recommended limit for photon energies from 65 keV to 1.25 MeV. The study showed encouraging results for using electronic dosimeters in personal dosimetry.
The electron affinities of indium and thallium were measured in separate experiments using the laser-photodetachment electron spectroscopy technique. The measurements were performed at the University of Nevada, Reno. Negative ion beams of both indium and thallium were extracted from a cesium-sputter negative ion source, and mass analyzed using a 90{sup o} bending magnet. The negative ion beam of interest was then crossed at 90{sup o} with a photonbeam from a cw 25-Watt Ar{sup +} laser. The resulting photoelectrons were energy analyzed with a 160{sup o} spherical-sector spectrometer. The electron affinity of In({sup 2}P{sub 1/2}) was determined to be 0.404 {+-} 0.009 eV and the electron affinity of thallium was determined to be 0.377 {+-} 0.013 eV. The fine-structure splittings in the ground states of the negative ions were also determined. The experimental measurements will be compared to several ...
Megavoltage photon intensity-modulated radiation therapy (IMRT) is typically used in the treatment of prostate cancer at our institution. Approximately 1% to 2% of patients with prostate cancer have hip prostheses. The presence of the prosthesis usually complicates the planning process because of dose perturbation around the prosthesis, radiation attenuation through the prosthesis, and the introduction of computed tomography artifacts in the planning volume. In addition, hip prostheses are typically made of materials of high atomic number, which add uncertainty to the dosimetry of the prostate and critical organs in the planning volume. When the prosthesis is bilateral, treatment planning is further complicated because only a limited number of beam angles can be used to avoid the prostheses. In this case study, we will report the observed advantages of using noncoplanar beams in the delivery of IMRT to a prostate cancer ...
A method for detecting electrons emitted as secondary particles by photon incidence to a specimen, as well as a method of using the photons emitted by electron incidence as detecting particles are explained. Pd-Si(100)2{times}1 system is adopted for a case study of using photo-electron spectroscopy where synchrotron emitted light in soft X-ray region is used as the incident light. Pd atoms are deposited little by little on clean Si surface to investigate the electron structure of the surface, and the interface electron structure after bonded formation of Pd(thin film)-Si(substrate) is estimated. Radiation soft X-ray spectroscopy is employed to observe the real state of the bonded interface of Pd(thin film)-Si(substrate) prepared by depositing Pd film in a short period of time. In the case of radiation soft X-ray spectroscopy with electron beam excitation, bonded system of thin film and substrate can be investigated by ...
In this report, I surveyed physics potential of the {gamma}{gamma} option of a linear e{sup +}e{sup -} collider with the following questions in mind: What new discovery can be expected at a {gamma}{gamma} collider in addition to what will be learned at its 'parent' e{sup +}e{sup -} linear collider? By taking account of the hard energy spectrum and polarization of colliding photons, produced by Compton back-scattering of laser light off incoming e{sup -} beams, we find that a {gamma}{gamma} collider is most powerful when new physics appears in the neutral spin-zero channel at an invariant mass below about 80% of the c.m. energy of the colliding e{sup -}e{sup -} system. If a light Higgs boson exists, its properties can be studied in detail, and if its heavier partners or a heavy Higgs boson exists in the above mass range, they may be discovered at a {gamma}{gamma} collider. CP property of the scalar sector can be explored in ...
In this report, I surveyed physics potential of the #gamma##gamma# option of a linear e"+e"- collider with the following questions in mind: What new discovery can be expected at a #gamma##gamma# collider in addition to what will be learned at its 'parent' e"+e"- linear collider? By taking account of the hard energy spectrum and polarization of colliding photons, produced by Compton back-scattering of laser light off incoming e"- beams, we find that a #gamma##gamma# collider is most powerful when new physics appears in the neutral spin-zero channel at an invariant mass below about 80% of the c.m. energy of the colliding e"-e"- system. If a light Higgs boson exists, its properties can be studied in detail, and if its heavier partners or a heavy Higgs boson exists in the above mass range, they may be discovered at a #gamma##gamma# collider. CP property of the scalar sector can be explored in detail by making use of linear polarization of the ...
The research supported by this Department of Energy contract has primarily been devoted to the study of the electronic properties of surfaces with sub-micron size. In previous years, we have studied the photoexcitation of electrons from field emission tips by a focussed Argon-ion laser beam tuned to operate at specific photon energy. The photoexcited electrons escape into the vacuum by tunneling through a surface potential barrier which is distorted by the application of a strong electric field. The interest in these experiments lies in a better understanding of the photoexcitation process at low photon energies. The techniques that have been developed directly measure the excited state energy distribution of electrons emitted through the surface potential barrier. The basic information gained from this research is relevant to opto-electronic devices which rely on photoexcitation of electrons in the presence of strong ...
A technique capable of measuring the electron energy fluence spectra in a scattering medium was designed. These measurements were performed by setting a bremsstrahlung conversion target on the surface of a phantom, at an intermediate depth, and at a depth equal to electron mean range. The bremsstrahlung produced by the deceleration of electrons in the target was passed through an air channel in the phantom and passed forward by a pinhole collimator into a Na(Tl) detector. The measured pulse height data were unfolded to correct for the distortion of the spectrometer system by using the FORIST unfolding code. The unfolded bremsstrahlung spectra represent the electron energy fluence spectra convolution with the bremsstrahlung produced in the target. To generate the electron energy fluence spectra, the unfolded bremsstrahlung spectra were deconvoluted by using the MAZE2 unfolding code. CYLTRAN, a coupled electron-photon Monte Carlo transport code, was used to produce ...
The L shell fluorescence cross-sections of the elements in range 45Z50 have been determined at 8keV using Synchrotron radiation. The individual L X-ray photons, Ll, La, LbI, LbII, LgI and LgII produced in the target were measured with high resolution Si(Li) detector. The experimental set-up provided a low background by using linearly polarized monoenergetic photonbeam, improving the signal-to-noise ratio. The experimental cross-sections obtained in this work were compared with available experimental data from Scofield [1,2] Krause [3,4] and Scofield and Puri et al. [5,6]. These experimental values closely agree with the theoretical values calculated using Scofield and Krause data, except for the case of Lg, where values measured of this work are slighter higher.
We present a new photonic technology and demonstrate that it allows for precise immobilisation of biomolecules to sensor surfaces. The technology secures spatially controlled molecular immobilisation since immobilisation of each molecule to a support surface can be limited to the focal point of the ultraviolet (UV) beam, as small as a few micrometers. We can immobilise molecules according to any pattern, from classical microarrays to diffraction patterns creating unique watermarking safety patterns. Given that suitable protein markers exists for all relevant diseases it is entirely feasible to test for a range of disease indicators (antigens and other markers) in a single test. Few micrometer spotsize allows for a virtually unlimited number of protein spots in a multipotent microarray. This new technology produces radically new photonics based microarray sensing technology and watermarking and has clear potential for ...
The photon rupture method, by which oxide film and metal are removed by focused pulsed Nd-YAG laser beam irradiation, was applied to form artificial micro-pits in Zn-5 mass% Al alloy-coated steel. The zinc alloy-coated layer was removed by pulsed laser irradiation treatment for about one second in a neutral buffer solution with NaCl. The rest potential transient with the laser treatment was measured. In the early stage of the laser treatment the rest potential of zinc alloy-coated steel changed to the negative direction immediately after every irradiation of a laser pulse and then returned to the previous value. However, after the steel substrate was exposed to the solution, the rest potential moved to the positive direction immediately after every irradiation of a laser pulse and then returned to the previous value. The amplitude and duration of the potential change after the laser irradiation increased with repetition of laser irradiation, ...
Electron interference in the presence of nonclassical microwaves with frequency {omega}{sub 1} and classical RF radiation with frequency {omega}{sub 2}, is studied. The relative phase factor between the two electron beams is a quantum-mechanical operator, whose expectation value with regard to the density matrix describing the nonclassical microwaves, determines the interference. It is shown that the visibility of the time-averaged intensity is a constant for all irrational values of {omega}{sub 1}/{omega}{sub 2}, and shows peaks (fractional Shapiro steps) at all rational values. These peaks can provide direct experimental evidence of the highly nonlinear processes of frequency conversion from {ital N} photons with frequency {omega}{sub 1}, to {ital M} photons with frequency {omega}{sub 2}. Results for various types of nonclassical microwaves (e.g., coherent states, squeezed states, number eigenstates, etc.) are derived and ...
The O({alpha}) electroweak radiative corrections to {gamma}{gamma}{yields}WW{yields}4f within the electroweak standard model are calculated in double-pole approximation (DPA). Virtual corrections are treated in DPA, leading to a classification into factorizable and non-factorizable contributions, and real-photonic corrections are based on complete lowest-order matrix elements for {gamma}{gamma}{yields}4f+{gamma}. Soft and collinear singularities appearing in the virtual and real corrections are combined alternatively in two different ways, namely by using the dipole subtraction method or by applying phase-space slicing. The radiative corrections are implemented in a Monte Carlo generator called Coffer {gamma}{gamma} - the computer code can be obtained from the authors upon request - which optionally includes anomalous triple and quartic gauge-boson couplings in addition and performs a convolution over realistic spectra of the photon ...
The O(#alpha#) electroweak radiative corrections to #gamma##gamma##->#WW#->#4f within the electroweak standard model are calculated in double-pole approximation (DPA). Virtual corrections are treated in DPA, leading to a classification into factorizable and non-factorizable contributions, and real-photonic corrections are based on complete lowest-order matrix elements for #gamma##gamma##->#4f+#gamma#. Soft and collinear singularities appearing in the virtual and real corrections are combined alternatively in two different ways, namely by using the dipole subtraction method or by applying phase-space slicing. The radiative corrections are implemented in a Monte Carlo generator called Coffer #gamma##gamma# - the computer code can be obtained from the authors upon request - which optionally includes anomalous triple and quartic gauge-boson couplings in addition and performs a convolution over realistic spectra of the photon ...
The research supported by this Department of Energy contract has primarily been devoted to the study of the electronic properties of surfaces with sub-micron size. In previous years, we have studied the photoexcitation of electrons from field emission tips by a focussed Argon-ion laser beam tuned to operate at specific photon energy. The photoexcited electrons escape into the vacuum by tunneling through a surface potential barrier which is distorted by the application of a strong electric field. The interest in these experiments lies in a better understanding of the photoexcitation process at low photon energies. The techniques that have been developed directly measure the excited state energy distribution of electrons emitted through the surface potential barrier. The basic information gained from this research is relevant to opto-electronic devices which rely on photoexcitation of electrons in the presence of strong ...
The Fast Flux Test Facility (FFTF) is a 400 MW(th) sodium cooled reactor and is the largest test reactor of its type in the world. It was designed and is being operated to serve two purposes: gaining liquid metal system experience and serving as a test bed for fuels and materials. During test operations it is possible that cladding breaches and escape of fission gas to the reactor cover gas region can occur. To identify the source of such a leak all 78 fuel pin assemblies contain ''gas tag'' with a unique ''tag'' mixture in each assembly. The mass spectrometric identification of tag isotope ratios makes possible rapid location and thus faster removal (if required) of breached test pins.
This work describes an experimental verification of the two-photon dose calculation engines available on the Helax-TMS (version 6.1) commercial radiotherapy treatment planning system. The performance of the pencil beam convolution and the collapsed cone superposition algorithms was examined for 4, 6, 15 MV beams, under a range of clinically relevant irradiation geometries. Comparisons against measurements were carried out in terms of absolute dose, thus assessment of the accuracy of monitor unit (MU) calculations was also carried out. Results show that both algorithms agree with measurement to acceptable tolerance levels in most cases in homogeneous water-equivalent media irradiated under full scatter conditions. The collapsed cone algorithm slightly overestimates the penumbra width and this is mainly due to discretization effects of the fluence matrix. The accuracy of this algorithm strongly depends on the resolution of ...
In July 2005 a new algorithm was released by Varian Medical Systems for the Eclipse planning system and installed in our institute. It is the anisotropic analytical algorithm (AAA) for photon dose calculations, a convolution/superposition model for the first time implemented in a Varian planning system. It was therefore necessary to perform validation studies at different levels with a wide investigation approach. To validate the basic performances of the AAA, a detailed analysis of data computed by the AAA configuration algorithm was carried out and data were compared against measurements. To better appraise the performance of AAA and the capability of its configuration to tailor machine-specific characteristics, data obtained from the pencil beam convolution (PBC) algorithm implemented in Eclipse were also added in the comparison. Since the purpose of the paper is to address the basic performances of the AAA and of its configuration ...
I review the physic prospects for high energy photonphoton colliders, emphasizing results presented at the LBL Gamma Gamma Collider Workshop. Advantages and difficulties are reported for studies of QCD, the electroweak gauge sector, supersymmetry, and electroweak symmetry breaking.
I review the physics prospects for high energy photonphoton colliders, emphasizing results presented at the LBL Gamma Gamma Collider Workshop. Advantages and difficulties are reported for studies of QCD, the electroweak gauge sector, supersymmetry, and electroweak symmetry breaking. ((orig.)).
I review the physic prospects for high energy photonphoton colliders, emphasizing results presented at the LBL Gamma Gamma Collider Workshop. Advantages and difficulties are reported for studies of QCD, the electroweak gauge sector, supersymmetry, and electroweak symmetry breaking.
I review the physics prospects for high energy photonphoton colliders, emphasizing results presented at the LBL Gamma Gamma Collider Workshop. Advantages and difficulties are reported for studies of QCD, the electroweak gauge sector, supersymmetry, and electroweak symmetry breaking. ((orig.)).
Detectors for a photon-photon collider are envisaged using as guide-lines the physics goals and the interaction point environment. Production of SUSY Higgs scalar and pseudo-scalar is emphasized. Some aspects of the interaction point environment are discussed. ((orig.)).
The performance requirements of the Advanced Photon Source (APS) challenge the control system in a number of areas. This paper will review a few applications of advanced technology in the control and monitoring of the APS. The application of digital signal processors (DSPs) and techniques will be discussed, both from the perspective of a large distributed multiprocessor system and from that of embedded systems. In particular, two embedded applications will be highlighted, a beam position monitor processor and a DSP-based power supply controller. Fast data distribution is often a requirement. The application of a high-speed network based on reflective memory will also be discussed in the context of the APS global orbit feedback system. Timing systems provide opportunities to apply technologies such as high-speed logic and fiber optics. Examples of the use of these technologies will also be included. Finally, every modern accelerator control ...
We present the effects of heavy CP-even (H) and CP-odd (A) Higgs bosons on the production cross section of the process {gamma}{gamma}{yields}tt at the energy around the mass poles of the Higgs bosons. It is found that interference between H and A with small mass gap, as well as the ones between Higgs bosons and continuum, contributes to the cross section, if the photonbeams are polarized and if we observe the helicity of the top quarks. It is demonstrated in the framework of the minimal supersymmetric extension of the standard model that the H and A contributions can be sizable at future {gamma}{gamma} colliders for small values of tan {beta}. The methods to measure the CP-parity of the Higgs boson are also presented. The statistical significance of detecting the Higgs signals and measuring the Higgs CP-parity is evaluated. (orig.)
We present the effects of heavy CP-even (H) and CP-odd (A) Higgs bosons on the production cross section of the process #gamma##gamma##->#tt at the energy around the mass poles of the Higgs bosons. It is found that interference between H and A with small mass gap, as well as the ones between Higgs bosons and continuum, contributes to the cross section, if the photonbeams are polarized and if we observe the helicity of the top quarks. It is demonstrated in the framework of the minimal supersymmetric extension of the standard model that the H and A contributions can be sizable at future #gamma##gamma# colliders for small values of tan #beta#. The methods to measure the CP-parity of the Higgs boson are also presented. The statistical significance of detecting the Higgs signals and measuring the Higgs CP-parity is evaluated. (orig.)
InP-quantum dots (QDs) are promising sources of single-photons and as active laser medium, emitting in the red part of the visible spectrum and thus in the range of the highest sensitivity of current silicon detectors. The self assembled QDs were grown by metal organic vapor phase epitaxy and are embedded in between distributed Bragg reflectors (DBRs), afterwards the sample was processed by a Focused Ion Beam to fabricate micro-pillars. The DBRs and the high refractive index step between pillar and air results in a three dimensional mode confinement and highly directed emission and thus higher intensity. We have investigated the mode spectra by micro-photoluminescence measurements for different pillar diameters and compared the spectra with a theoretical model showing up good consistency. Q-factors up to 3600 were achieved.
The MCNPE-BO and MCNP4 Monte Carlo electron-photon codes were used to calculate the dose equivalent per unit fluence at various depths in tissue-equivalent slab phantoms for broad parallel beams of monoenergetic electrons with energies from 50 keV to 10 MeV. The study was carried out in the framework of the activities of a ICRP/ICRU Joint Task Group with the support of EURADOS WG4 (Numerical Dosimetry). Some preliminary results and comparisons as well as a general discussion on the performances of the codes are presented, demonstrating quite a satisfactory agreement among the results obtained using the two codes and those of other authors. (author).
Efficient, low-temperature conversion of infrared light into visible light (red, orange, green) is reported at single heterojunctions and undoped quantum wells of GaAs and ordered Al_xGa_1_-_xInP_2; an increase in photon energy of 700 meV is obtained. The signal originates from the high-band-gap layers and disappears only if the excitation energy is tuned below the GaAs band gap. The intensity of the up-converted photoluminescence (PL) is found to decrease significantly slower with increasing temperature than that of the regular PL and it remains observable up to 200 K. Interface-induced cold Auger processes along with the presence of trapped states for both electrons and holes in these ordered alloys account for this nonlinear mechanism. A colinear double-beam experiment confirms this. copyright 1996 The American Physical Society.
An image-analysis system, based on commercially available data visualization software (IDL [1]), allows convenient interaction with image data while still providing calculated beam parameters at a rate of up to 2 Hz. Image data are transferred from the IOC to the workstation via EPICS [2] channel access. A custom EPICS record was created in order to overcome the channel access limit of 16k bytes per array. The user can conveniently calibrate optical transition radiation (OTR) and fluorescent screens, capture background images, acquire and average a series of images, and specify several other filtering and viewing options. The images can be saved in either IDL format or APS-standard format (SDDS [3]), allowing for rapid postprocessing of image data by numerous other software tools.
Successful electron capture dissociation (ECD) Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) applications to peptide and protein structural analysis have been enabled by constant progress in implementation of improved electron injection techniques. The rate of ECD product ion formation has been increased to match the liquid chromatography and capillary electrophoresis timescales, and ECD has been combined with infrared multiphoton dissociation in a single experimental configuration to provide simultaneous irradiation, fast switching between the two techniques, and good spatial overlap between ion, photon, and electron beams. Here we begin by describing advantages and disadvantages of the various existing electron injection techniques for ECD in FT-ICR MS. We next ...
The aim of this work was to compare dose calculation algorithm results at orthovoltage energies for a phantom composed of a bone slab in water. The calculation methods investigated were: no correction, ETAR, Batho, convolution/superposition and Monte Carlo. All algorithms calculated depth dose curves in a water phantom within 4% of experiment. However in the bone phantom, differences of over 40% between the No Correction / ETAR / Batho / Convolution and Monte Carlo results in the 1 cm thick bone slab were observed. These differences are predominantly because the algorithms do not account for the differing atomic number of the bone compared to water The increased dose to bone and the tissue adjacent to the bone interface should be considered when treating with orthovoltage photons. Copyright (1998) Australasian Physical and Engineering Sciences in Medicine
Since 1979, scientists and engineers at the Los Alamos National Laboratory have designed, constructed, and operated a radio-frequency (RF) linac free-electron laser (FEL) at wavelengths from 9 to 45 /mu/m. Coupled with success of other research centers investigating wavelengths from the visible to far-infrared, Los Alamos is now proposing a vacuum-ultraviolet and soft x-ray (referred to henceforth as extreme ultraviolet, (XUV)) FEL oscillator/Self-Amplified Spontaneous Emission amplifier with beam energies ranging from 100 MeV to 1 GeV. This paper will focus on the first milestone of the proposed Los Alamos XUV project, i.e., a 250-MeV linac with approximately 50 mA of average current, producing photons with wavelengths below 1000 /angstrom/. 3 refs., 3 figs.
The noninvasive assessment of cardiac function is of first importance for the diagnosis of cardiovascular diseases. Among all medical scanners only a few enables radiologists to evaluate the local cardiac...Full Text Available
The development of chromatin immunoprecipitation methods coupled with DNA microarray (ChIP-chip) technology has enabled genome-wide identification of cis-DNA regulatory elements to which transcription...Full Text Available
In this study we have profiled the free sterol content of cerebrospinal fluid by a combination of charge tagging and liquid chromatography-tandem mass spectrometry. Surprisingly, the most abundant cholesterol...Full Text Available
Numerous xenobiotics, including therapeutics agents, are substrates for bioactivation to electrophilic reactive intermediates that may covalently modify biomolecules. Selective estrogen receptor...Full Text Available
The profusion of online digital images presents new challenges for image indexing. Images have always been problematic to describe and catalogue due to lack of inherent textual data and ambiguity of meaning. An alternative to time-consuming professionally-applied metadata has been sought in the form of tags, simple keywords that form a flat structure known as distributed classification, or more popularly as a folksonomy. This research aims to increase understanding of why people tag and how effective they find it for searching, using as the focus. Open-ended questionnaires were sent out to members of the photo-sharing website Flickr, with the opportunity to post comments to an online discussion space. There is also a systematic comparison between a tag-based system and a more traditional controlled vocabulary, to test out the claims made regarding the suitability of tagging for searching and browsing. ...
To study the effect of agonist on the TRH (thyrotrophin-releasing hormone) receptor protein, an epitope-tagged receptor was stably expressed in HEK-293 cells (human embryonic kidney 293 cells) and receptor...Full Text Available
BackgroundGenotyping analysis using capillary DNA sequencing with fluorescently labeled primer pairs obtained by polymerase chain reaction (PCR) is widely used, but is expensive....Full Text Available
The lipid fractions of residues from historical pharmaceutical ointments were analysed by reversed-phase liquid chromatography coupled with atmospheric pressure chemical ionization and mass spectrometer detection. The residues were contained in a series of historical apothecary jars, dating from the eighteenth century and conserved at the "Aboca Museum" in Sansepolcro (Arezzo, Italy) and at the pharmacy of the "Real Cartuja de Valldemossa" in Palma de Majorca (Spain). The analytical protocol was set up using a comparative study based on the evaluation of triacylglycerol (TAG) compositions in raw natural lipid materials and in laboratory-reproduced ointments. These ointments were prepared following pharmaceutical recipes reported in historical treatises and used as reference materials. The reference materials were also subjected to stress treatments in order to evaluate the modification occurring in the TAG profiles as an effect of ageing. ...
This paper reports on three-dimensional continuous-energy coupled neutron-gamma Monte Carlo models of the Advanced Neutron Source (ANS) final preconceptual and conceptual reference core designs developed using the Monte Carlo Neutron and Photon transport code (MCNP) Version 3b. These models contain the reactor core with control rods, the heavy water reflector tank with shutdown rods and some beam tubes, and the outer light water pool. Eighty homogenized fuel zones per fuel element are used to represent the radial and axial {sup 235}U fuel distribution. These models are the most sophisticated, physically accurate reactor physics models of the ANS currently available. The use of MCNP methods and applications to the ANS are demonstrated. Beam tube studies, coolant voiding studies, and many criticality studies have already been performed, as have studies with variance reduction techniques. In comparison with deterministic ...
Focused ion beam (FIB) milling techniques are presented aiming at the manipulation of both tin dioxide (SnO_2) inverted opals and polystyrene (PS) direct opals. Different SnO_2 opals are considered in order to estimate the regularity of their bulk after the production. A SnO_2 mesoporous monolith is FIB micromachined to make it suitable for optical applications. PS direct opals are structured by FIB milling at different scales. Ordered arrays of PS opals are modified by selectively removing a single sphere. In performing this task, we discuss the effects on the FIB milling due to the gas-assisted enhanced etching and to the binding of the nearest neighbours. Techniques to achieve imaging of PS opals in absence of a conductive coating are also brought up. Furthermore, isolated PS spheres are drilled with or without enhanced etching in order to produce controlled defects on them. The FIB-assisted manipulations we show may find potential applications in the field of ...
Free electron laser (FEL) facilities as the FELI FEL Facility are proposed, for which a 150-MeV linac type injector for a Saga synchrotron light source (SLS) is employed in FEL mode. The linac has two operating modes; short macropulse mode a 1 #mu#s at 150 MeV for injection to a 1 - 1.3-GeV third generation type storage ring and long macropulse mode of 12 #mu#s at 100 MeV for four FEL Facilities. The macropulse beam consists of a train of several ps, 0.6 nC microbunches (peak current 100 A) repeating at 89.25 MHz. We are aiming to supply high power level photonbeams covering an attractive wavelength range from 0.05 nm (25 keV) to 200 #mu#m (0.006 eV) for scientific researches, bio-medical and industrial applications, using the Saga third generation type SLS with a superconducting wiggler and the proposed four FEL Facilities. (author)
The results that can be expected by e#gamma# and #gamma##gamma# colliders in future are summarized. e#gamma# and #gamma##gamma# colliders have many fine possibilities, and are the economical selection for utilizing future e"+e"- colliders more effectively. e#gamma# and #gamma##gamma# colliders were proposed by former USSR researchers at the beginning of 1980s, but recently, the prospect of realizing future e"+e"- collision type linear accelerator projects has become high, they have become to be considered seriously as the option of remodeling them. The high energy photonbeam of e#gamma# and #gamma##gamma# colliders is obtained by causing Compton reverse scattering, irradiating laser beam to the electron beam of e"+e"- accelerators. The production of #gamma#-beam is explained. As for the physics noteworthy in e#gamma# colliders, abnormal gauge coupling, the formation of Higgs ...
In radiotherapy treatment planning, convolution/superposition algorithms currently represent the best practical approach for accurate photon dose calculation in heterogeneous tissues. In this work, the implementation, accuracy and performance of the FFT convolution (FFTC) and multigrid superposition (MGS) algorithms are presented. The FFTC and MGS models use the same 'TERMA' calculation and are commissioned using the same parameters. Both models use the same spectra, incorporate the same off-axis softening and base incident lateral fluence on the same measurements. In addition, corrections are explicitly applied to the polyenergetic and parallel kernel approximations, and electron contamination is modelled. Spectra generated by Monte Carlo (MC) modelling of treatment heads are used. Calculations using the MC spectra were in excellent agreement with measurements for many linear accelerator types. To speed up the calculations, a number of calculation techniques were ...
The results that can be expected by e{gamma} and {gamma}{gamma} colliders in future are summarized. e{gamma} and {gamma}{gamma} colliders have many fine possibilities, and are the economical selection for utilizing future e{sup +}e{sup -} colliders more effectively. e{gamma} and {gamma}{gamma} colliders were proposed by former USSR researchers at the beginning of 1980s, but recently, the prospect of realizing future e{sup +}e{sup -} collision type linear accelerator projects has become high, they have become to be considered seriously as the option of remodeling them. The high energy photonbeam of e{gamma} and {gamma}{gamma} colliders is obtained by causing Compton reverse scattering, irradiating laser beam to the electron beam of e{sup +}e{sup -} accelerators. The production of {gamma}-beam is explained. As for the physics noteworthy in e{gamma} colliders, abnormal gauge coupling, ...
An extensive set of benchmark measurement of PDDs and beam profiles was performed in a heterogeneous layer phantom, including a lung equivalent heterogeneity, by means of several detectors and compared against the predicted dose values by different calculation algorithms in two treatment planning systems. PDDs were measured with TLDs, plane parallel and cylindrical ionization chambers and beam profiles with films. Additionally, Monte Carlo simulations by meansof the PENELOPE code were performed. Four different field sizes (10x10, 5x5, 2x2, and1x1 cm"2) and two lung equivalent materials (CIRS, #rho#_e"w=0.195 and St. Bartholomew Hospital, London, #rho#_e"w=0.244-0.322) were studied. The performance of four correction-based algorithms and one based on convolution-superposition was analyzed. The correction-based algorithms were the Batho, the Modified Batho, and the Equivalent TAR implemented in the Cadplan (Varian) treatment planning system and ...
The authors present here several recent measurements involving associate production of photons and jets at the Tevatron. In particular, inclusive photon + met from D0, and photon + b-jets and photon + b-jet + leptons + MET from CDF are described in some detail. These measurements offer a good test of QCD predictions in rather complex final states.
Calgary-based TAG Oil is an exploration company that manages 4.1 million acres of major producing oil and gas fields in New Zealand. The enormous Maui field, with 4 tcf of natural gas in place, has dominated the gas market in New Zealand by meeting nearly 90 per cent of the country's energy demand at costs much lower than world prices. However, the maturing field is in decline and will cease production by 2008. New gas field discoveries will only meet 60 per cent of the country's energy requirements for 5 additional years. Unless new large reserves of gas are discovered, the supply and demand situation will get worse. Lead time to place new production on-stream requires 5 to 10 years, which creates a large supply gap over the next decade. Public resistance to coal-fired power plants, new hydroelectric dams and nuclear power has left the country with no viable alternative to natural gas. TAG Oil has taken this unique opportunity to create value ...
The use of platinum(II) complexes as tags and probes for biomolecules is indeed advantageous for their reactivities can be selective for certain purposes through an interplay of mild reaction conditions and of the ligands bound to the platinum. The use of {sup 195}Pt NMR as a method of detecting platinum and its interactions with biomolecules was carried out with the simplest model of platinum(II) tagging to proteins. Variable-temperature {sup 195}Pt NMR spectroscopy proved useful in studying the stereodynamics of complex thioethers like methionine. The complex, Pt(trpy)Cl{sup +}, with its chromophore has a greater potential for probing proteins. It is a noninvasive and selective tag for histidine and cysteine residues on the surface of cytochrome c at pH 5. The protein derivatives obtained are separable, and the tags are easily quantitated and differentiated through the metal-to-ligand charge transfer ...
The beam-beam interaction in the Tevatron produce the betatron tune spread in each bunch and a bunch-to-bunch tune spread. The tune spread sets limits on bunch intensity and luminosity. The beam-beam effects for antiprotons are usually more severe since the proton bunch population is higher. The beam-beam effects for antiprotons can in principle be compensated with the use of an electron beam with a corresponding charge density. The status of studies of possibilities of the beam-beam compensation is reviewed in this paper.
In vivo two-photon imaging through the pupil of the primate eye has the potential to become a useful tool for functional imaging of the retina. Two-photon excited fluorescence images...Full Text Available
The proton beam has an advantage of the sharp dose falloff in dose distribution called Bragg peak while conventional radiation therapy modalities such as photons exhibit considerable amount of exit dose. To take advantage of this property it is important to know the exact location of the distal dose falloff. An error can cause overdose to the normal tissue or underdose to the tumor volume. The only way of finding out the dose distribution in-situ in particle therapy is to measure the gammas produced by nuclear reactions with tissue materials. Two kinds of gammas can be used: one is prompt gamma and the other is coincident gamma from the positron-emission isotopes. We chose to detect prompt gammas, and developed a prompt gamma scanning system (PGS). The proton beams of the proton therapy facility at National Cancer Center were used. The gamma distribution was compared to the dose distribution measured by an ionization ...
Many social Web sites allow users to publish content and annotate with descriptive metadata. In addition to flat tags, some social Web sites have recently began to allow users to organize their content and metadata hierarchically. The social photosharing site Flickr, for example, allows users to group related photos in sets, and related sets in collections. The social bookmarking site Del.icio.us similarly lets users group related tags into bundles. Although the sites themselves don't impose any constraints on how these hierarchies are used, individuals generally use them to capture relationships between concepts, most commonly the broader/narrower relations. Collective annotation of content with hierarchical relations may lead to an emergent classification system, called a folksonomy. While some researchers have explored using tags as evidence for learning folksonomies, we believe that hierarchical relations described ...
Full text: A semiempirical algorithm for absorbed dose calculation at off-axis points in irregular beams was implemented. It is well known that semiempirical methods are very useful because of their easy implementation and its helpfulness in dose calculation in the clinic. These methods can be used as independent tools for dosimetric calculation in many applications of quality assurance. However, the applicability of such methods has some limitations, even in homogeneous media, specially at off axis points, near beam fringes or outside the beam. Only methods derived from tissue-air-ratio (TAR) or scatter-maximum-ratio (SMR) have been devised for those situations, many years ago. Despite there have been improvements for these manual methods, like the Sc-Sp ones, no attempt has been made to extend their usage at off axis points. In this work, a semiempirical formalism was introduced, based on the works of Venselaar et al. ...
Prostate and cervical cancer patients are often treated with external X-ray beams of bi-lateral incidence. Such treatment may incur some dose effect that cannot be predicted precisely in commercial treatment planning systems (TPS) for patients having undergone total hip replacement. This study performs a Monte Carlo (MC) simulation and an analytical calculation (convolution superposition algorithm which is implemented in ADAC TPS) of a 6 MV, 5x5 cm"2 X-ray beam incident into water with the existence of hip prosthesis, e.g. Ti6Al4V and CoCrMo alloy. The results indicate that ADAC TPS cannot precisely account for the scatter and backscatter radiation that a metal hip prosthesis causes. For percent depth dose (PDD) curves, the maximum underdosage of ADAC TPS up to 5 mm above the interface between dense material and water is 5%, 20% and 27% for PDD_B_o_n_e, PDD_T_i and PDD_C_o, respectively. The dose re-buildup, which occurs behind the hip region, ...
A specific application of single photon emission tomography to the relative quantitation of the pituitary region is described together with the results obtained in 19 patients with pituitary adenoma...Full Text Available
Nano photonic materials are synthetically manufactured crystals at the nano scale with the target of creating a microstructure with a special electro-magnetic periodicity. Such nano photonic materials have the ability to control light propagation and thus are capable of creating photonic bandgaps in the frequency domain. We propose using nano photonic crystals as sensors to detect microdamage in composite materials. We demonstrate using a simulation model that a nano photonic sensor attached to a composite bar experiences a significant change in its bandgap profile when damage is induced in the composite bar. The model predicts the frequency response of the nano photonic sensor using the transfer matrix method. A damage metric to evaluate the change in the frequency response is developed. Successful developments of nano photonic sensors ...
Encapsulation of a unique isotopic blend of krypton and xenon gas employs a special application of laser technology. The encapsulated gas is then used as the primary medium for detection and identification of failed nuclear fuel rods. The use of gas tagging as a means of detecting and identifying failed nuclear fuel rods has been successfully demonstrated and used by the Argonne National Laboratory, Experimental Breeder Reactor (EBR-2) Project, and the Westinghouse Hanford Company (WHC), Fast Flux Test Facility (FFTF) Fast Breeder Reactor Program. The Power Reactor and Nuclear Fuel Development Corporation (PNC) of Japan has selected this leak detection system for use in their MONJU Prototype Reactor fuel assemblies. The MONJU reactor is almost identical in design to the highly successful FFTF reactor, which is currently in standby status.
The Polarized Gamma-ray Observer (PoGOLite) is a balloon-borne instrument that will measure gamma-ray polarization in the energy range 25-80 keV from astronomical sources such as pulsars, accretion discs and jets from active galactic nuclei. The two additional parameters provided by such observations, polarization angle and degree, will allow these objects to be studied in a new way, providing information about their emission mechanisms and geometries. The instrument measures azimuthal scattering angles of photons within a close packed array of phoswich detector cells (PDCs) based on coincident detection of Compton scattering and photoelectric absorption. Each PDC comprises three different scintillating components and combines photon detection, active collimation and bottom anticoincidence into one single unit. The three parts are viewed by a photomultiplier tube (PMT) and pulse shape discrimination is used to identify signals from dierent ...
We present a Hubble Space Telescope image of the FRII radio galaxy 3C 401, obtained at 1.6 microns with the NICMOS camera in which we identify the infrared counterpart of the brightest region of the radio jet. The jet has a complex radio structure and brightens where bending occurs, most likely as a result of relativistic beaming. We analyze archival data in the radio, optical and X-ray bands and we derive its spectral energy distribution. Differently from all of the previously known optical extragalactic jets, the jet in 3C401 is not detected in the X-rays even in a long 48ksec X-ray Chandra exposure and the infrared emission dominates the overall SED. We propose that the dominant radiation mechanism of this jet is synchrotron. The low X-ray emission is then caused by two different effects: i) the lack of any strong external photon field and ii) the shape of the electron distribution. This affects the location of the synchrotron peak in the ...
We propose to investigate the in-medium properties of vector $\\omega$ mesons at the normal nuclear density in Ap(pA) collisions and at higher density in AA collisions at the ITEP accelerator facility TWAC. Using of the inverse Ap kinematics will permit us to study the $\\omega$ meson production in a wide momentum interval included the not yet explored range of small meson momenta relative to the projectile nuclei where the mass modification effect in nuclear matter is expected to be the strongest. Momentum dependence of the in-medium $\\omega$ meson width will be studied in the traditional pA kinematics. We intend to use the electromagnetic calorimeter for reconstruction of the $\\omega$ meson invariant mass by detecting photons from the $\\omega \\to \\pi^{0}\\gamma \\to 3\\gamma$ decay. The model calculations and simulations with RQMD generator show feasibility of the proposed experiment. Available now intensity of the ion beams provides a ...
The quality insurance in radiotherapy in the frame of highly complex technical process as Intensity modulated radiotherapy (I.M.R.T.) needs independent control of the delivered dose to the patient. Actually, up to now, most of the radiotherapy treatments rely only on computed dosimetry through a rather complicated series of linked simulation tool. This dosimetry approach requires also qualified treatment means based on cautious quality insurance procedures. However, erroneous parameters could be difficult to detect and systematical errors could happen leading to radiotherapy accidents. In this context, in vivo dosimetry has a critical role of final control of the delivered dose. As many beam incidences and ports are used for any photon therapy treatment, external control could be very tedious and time consuming. Therefore, innovations are needed for in vivo dosimetry to provide ergonomic and efficient tools for these controls. This paper ...
We study double Higgs boson production at future linear colliders while paying special attention to the option of high-energy and high-luminosity photonbeams. The main purpose is to examine the feasibility of {ital e}{sup +}{ital e}{sup {minus}}, {gamma}{ital e}, and {gamma}{gamma} colliders in order to establish bounds on the value of triple Higgs coupling, which could be crucial for understanding a spontaneous breaking mechanism. We consider mainly those cases of light and intermediate Higgs bosons, including an analysis of the electroweak backgrounds. The mass range {ital M}{sub {ital H}}{approximately}{ital M}{sub {ital Z}} is discussed separately. It is shown that for a light Higgs boson the {ital H}{sup 3} coupling can be visible, even at a future linear {ital e}{sup +}{ital e}{sup {minus}} collider at 500 GeV. For an intermediate Higgs boson, a collider with TeV energies is suitable for investigations. We estimate the bounds on the ...
We study double Higgs boson production at future linear colliders while paying special attention to the option of high-energy and high-luminosity photonbeams. The main purpose is to examine the feasibility of e"+e"-, #gamma#e, and #gamma##gamma# colliders in order to establish bounds on the value of triple Higgs coupling, which could be crucial for understanding a spontaneous breaking mechanism. We consider mainly those cases of light and intermediate Higgs bosons, including an analysis of the electroweak backgrounds. The mass range M_H#approx#M_Z is discussed separately. It is shown that for a light Higgs boson the H"3 coupling can be visible, even at a future linear e"+e"- collider at 500 GeV. For an intermediate Higgs boson, a collider with TeV energies is suitable for investigations. We estimate the bounds on the anomalous H"3 coupling which can be experimentally established at future linear colliders. copyright 1996 The American Physical ...
A critical issues study of a symmetric illumination, direct drive laser fusion reactor called SIRIUS has been conducted. In particular, the uniformity requirements for direct drive targets have been assessed and it is shown that respectable gains (more than 60) could be obtained at modest (2MJ) KrF laser energies. Previous ICF cavity designs have been examined for use in a symmetric illumination geometry and features from several designs have been combined into a dry wall cavity design with a radius of 8 meters. Neutronic and photonic analysis shows that the present SIRIUS cavity design can breed sufficient tritium (breeding ratio = 1.17) even with 32 laser ports penetrating the cavity. However, it was found that there are a few critical issues that remain to be solved before a self-consistent reactor design could be initiated. Radiation damage to final optics, thermal performance of SiC tiles on the SIRIUS cavity wall, and performance of direct drive targets to ...
The NPDGamma Experiment measures the parity-violating correlation A{sub {Gamma}Y} between neutron spin and photon momentum in the reaction {rvec n} + p {yields} d + {gamma}. Knowledge of A{sub {Gamma}Y} and other parity-violating observables in few-body nuclear systems will provide constraints for a parameterized description of {Delta}S = 0 parity-violating phenomena free from complications of nuclear structure. The NPDGamma experiment uses a polarized cold pulsed neutron beam, a liquid parahydrogen target, and a cylindrical array of 48 CsI(Tl) scintillation detectors operated in current mode to search for the asymmetry. NPDGamma recently completed the first phase of the program to measure A{sub {Gamma}Y} at the Los Alamos Neutron Science Center with the preliminary result A{sub {Gamma}Y} = (-1.2 {+-} 2.1(stat.) {+-} 0.1(sys.)) x 10{sup -7}, reproducing the previous upper limit from a measurement at a reactor facility. We discuss the ...
Molar extinction coefficients of some carbohydrates viz. L-arabinose (C5H10O5), D-glucose (C6H12O6), D-mannose (C6H12O6), D-galactose (C6H12O6), D(-) fructose (C6H12O6) and maltose (C12H24O12) in aqueous solutions have been determined at 81, 356, 511, 662, 1173 and 1332 keV by gamma ray transmission method in a narrow beam good geometry set-up. These coefficients have been found to depend upon the photon energy following a 4-parameter polynomial. These extinction coefficients for different sugars having the same molecular formula have same values varying within experimental uncertainty. Within concentration ranges studied, Beer--Lambert law is obeyed very well.
Efficient, low-temperature conversion of infrared light into visible light (red, orange, green) is reported at single heterojunctions and undoped quantum wells of GaAs and ordered Al{sub {ital x}}Ga{sub 1{minus}{ital x}}InP{sub 2}; an increase in photon energy of 700 meV is obtained. The signal originates from the high-band-gap layers and disappears only if the excitation energy is tuned below the GaAs band gap. The intensity of the up-converted photoluminescence (PL) is found to decrease significantly slower with increasing temperature than that of the regular PL and it remains observable up to 200 K. Interface-induced cold Auger processes along with the presence of trapped states for both electrons and holes in these ordered alloys account for this nonlinear mechanism. A colinear double-beam experiment confirms this. {copyright} {ital 1996 The American Physical Society.}
If the first (PopIII) stars were very massive, their final fate is to collapse into very massive black holes. Once a proto-black hole has formed into the stellar core, accretion continues through a disk. It is widely accepted, although not confirmed, that magnetic fields drive an energetic jet which produces a burst of TeV neutrinos by photon-meson interaction, and eventually breaks out of the stellar envelope appearing as a Gamma Ray Burst (GRB). Based on recent numerical simulations and neutrino emission models, we predict the expected neutrino diffuse flux from these PopIII GRBs and compare it with the capabilities of present and planned detectors as AMANDA and IceCube. If beamed into 1% of the sky, we find that the rate of PopIII GRBs is $\\le 4 \\times 10^6$ yr$^{-1}$. High energy neutrinos from PopIII GRBs could dominate the overall flux in two energy bands [$10^4 - 10^5$] GeV and [$10^5 - 10^6$] GeV of neutrino telescopes. The enhanced ...
The excitation cross sections by electron impact from the Cd II ground state to the laser upper state 5s_2 _2D/sub 5/2/ (Beutler state) and the laser lower state 5p _2P/sub 3/2/ (resonance state) have been measured by using a crossed-beam method of electrons and Cd"+ ions and a photon-counting method. The electron-energy region investigated was from the threshold energy (5.8 eV) for the excitation of the 5p _2P/sub 3/2/ state to 20 eV. It has been shown that the excitation cross section for the ionic Beutler state 5s_2 _2D/sub 5/2/ is of the order of 10"-_1_5 cm_2 and has a sharp peak near the threshold energy for the excitation. The excitation cross section for the resonance state 5p _2P/sub 3/2/ has also been of the order of 10"-_1_5 cm_2 and has a relatively broad maximum.
Background: the authors report on the conception and first clinical application of a donut-shaped high-dose configuration for proton therapy (PT). This approach allows one to intensify target volume dose coverage for targets encompassing a critical, dose-limiting structure - like here, the cauda equina -, whilst delivering minimal dose to other healthy structures surrounding the target, thereby reducing the integral dose. Methods and results: intensity-modulated PT methods (IMPT) for spot scanning were applied to create and deliver a donut-shaped high-dose configuration with protons, allowing treating > 75% of the target with at least 95% of the prescribed dose of 72.8 CGE, whilst restricting dose to the cauda equina to 60-65 CGE. Integral dose was lower by a factor of 3.3 as compared to intensity-modulated radiotherapy with photons (IMXT). Conclusion: IMPT and spot scanning technology allow a potentially clinically useful approach which is also applicable ...
Background: the authors report on the conception and first clinical application of a donut-shaped high-dose configuration for proton therapy (PT). This approach allows one to intensify target volume dose coverage for targets encompassing a critical, dose-limiting structure - like here, the cauda equina -, whilst delivering minimal dose to other healthy structures surrounding the target, thereby reducing the integral dose. Methods and results: intensity-modulated PT methods (IMPT) for spot scanning were applied to create and deliver a donut-shaped high-dose configuration with protons, allowing treating > 75% of the target with at least 95% of the prescribed dose of 72.8 CGE, whilst restricting dose to the cauda equina to 60-65 CGE. Integral dose was lower by a factor of 3.3 as compared to intensity-modulated radiotherapy with photons (IMXT). Conclusion: IMPT and spot scanning technology allow a potentially clinically useful approach which is also applicable to ...
We consider the possibility of detecting a heavy Higgs boson (m_H>2m_Z) in proposed #gamma##gamma# colliders through the semileptonic mode #gamma##gamma##->#H#->#ZZ#->#q bar ql"+l-. We show that due to the nonmonochromatic nature of the photonbeams produced by the laser-backscattering method, the resultant cross section for Higgs production is much smaller than the on-resonance cross section, and generally decreases with increasing collider energy. Although continuum ZZ production is expected to be negligible, we demonstrate the presence of, and calculate sizable backgrounds from, #gamma##gamma##->#l"+l-Z,q bar qZ, with Z#->#q bar q,l"+l-, respectively, and #gamma##gamma##->#t bar t#->#b bar bl"+l-#nu# bar #nu#. This channel may be used to detect a Higgs boson of mass m_H up to around 350 GeV at a 0.5 TeV e"+e- collider, assuming a nominal yearly luminosity of 10--20 fb"-"1.
A Digital X-ray imaging system using Compton backscattering has been developed to obtain a cross-sectional profile and mass loss of corroded lap-splices of aging aircraft from density variation. A slit-type camera was designed to focus on a small scattering volume inside the material, from which the backscattered photons are collected by a collimated scintillator detector for interpretation of material characteristics. The cross section of the lap-joint is scanned by moving the scattering volume through the thickness direction of the specimen. The mass loss of each layer has been estimated from a Compton backscatter A-scan to obtain the thickness of each layer including the aluminum sheet, the corrosion layer and the sealant. Quantitative information such as location and width of planar corrosion in the lap splices of fuselages is obtained by deconvolution using a nonlinear least-square error minimization method(BFGS method): A simple reconstruction model is also ...
GRR-1 is a 5MW open pool type research reactor with MTR-type fuel elements cooled and moderated by light water with beryllium reflectors at the two opposing sides of the core. A graphite thermal neutron column is adjusted to one side of the core. Six radial horizontal beam tubes are available, of which three contain in-pile collimators for neutron scattering instruments. The reactor is currently out of operation for inspection and refurbishment purposes. The core has been dismantled and the fuel elements are stored in the used fuel storage tank. The GRR-1 inspection and refurbishment plan involves inspection and eventually replacement of the reactor's primary cooling circuit. The health physics procedures to be implemented during inspection of the main water outlet are divided in three stages: a) pool dose rate survey from pool top, b) pool drainage by decreasing water level in steps and c) inspection of the water main outlet. urpose of the present work is the ...
During the last few decades, accuracy in photon and electron radiotherapy has increased substantially. This is partly due to enhanced linear accelerator technology, providing more flexibility in field definition (e.g. the usage of computer-controlled dynamic multileaf collimators), which led to intensity modulated radiotherapy (IMRT). Important improvements have also been made in the treatment planning process, more specifically in the dose calculations. Originally, dose calculations relied heavily on analytic, semi-analytic and empirical algorithms. The more accurate convolution/superposition codes use pre-calculated Monte Carlo dose 'kernels' partly accounting for tissue density heterogeneities. It is generally recognized that the Monte Carlo method is able to increase accuracy even further. Since the second half of the 1990s, several Monte Carlo dose engines for radiotherapy treatment planning have been introduced. To enable the use of a Monte Carlo treatment ...
The process of infrared multiple photon dissociation (IRMPD) of molecules is of great fundamental importance and has practical significance, such as isotope separation etc. Unfortunately, a clear insight into the process has been hindered by the bewildering array of important variables affecting MPD. The dissociation probability #gamma#(#phi#) i.e. the yield has been found to be a sensitive function of laser fluence #phi# along with numerous other parameters like laser frequency, gas pressure etc. We have shown that in single frequency IRMPD an accurate quantitative characterization of the dissociation probability can be adequately expressed by a 'power law' model with two fitting parameters namely critical fluence, #phi#c and multi photon order, m. This model was exploited in analysing our MPD results on various systems. However, the small isotope shift encountered in heavy elements and the sticking phenomenon observed in small light molecules ...
Two neutron emesis experiments were conducted at the Armed Forces Radiobiology Research Institute (AFRRI). In both experiments (described as Phase I and Phase II) the radiation dose required to cause emesis in 50% of subjects (ED50) was determined for both neutron reactor and gamma reactor source radiation. Emesis onset, offset and duration times post-exposure are reported. Neutrons were maximized from the reactor by passing the beam through a 15.25 cm (6 in.) thick lead wall to filter out gamma photons. Gamma rays were maximized by thermalizing neutrons in 30.5 cm (12 in.) of water, then absorbing the thermal neutrons in a gadolinium-cadmium shield. In Phase I, 28 dogs were exposed to radiation: 12 were exposed to gamma photons at the rate of 0.69 Gy/min and 16 were exposed to neutrons at 1.2 Gy/min. In Phase II, 58 dogs in 3 groups were exposed to radiation: 19 were exposed in the gamma group at 0.75 Gy/min, 20 were ...
Purpose: In this paper, we present an alternative to the originally proposed technique for the delivery of spatially fractionated radiation therapy (GRID) using multi-leaf collimator (MLC) shaped fields. We employ the MLC to deliver various pattern GRID treatments to large solid tumors and dosimetrically characterize the GRID fields. Methods and materials: The GRID fields were created with different open to blocked area ratios and with variable separation between the openings using a MLC. GRID designs were introduced into the Pinnacle"3 treatment planning system, and the dose was calculated in a water phantom. Ionization chamber and film measurements using both Kodak EDR2 and Gafchromic EBT film were performed in a SolidWater phantom to determine the relative output of each GRID design as well as its spatial dosimetric characteristics. Results: Agreement within 5.0% was observed between the Pinnacle"3 predicted dose distributions and the measurements for the majority of experiments ...
Detonators are used to convert electrical or other energy into an explosive output. This output can then be used to initiate further explosive charges. To aid in the development of explosive systems, it is important to characterize the output of detonators, in particularly the pressure produced. Recent advances over the last five years in high-speed digitizing oscilloscopes and high-bandwidth photodiodes, driven primarily by the telecommunications industry, have enabled the development of a new type of interferometer for measuring high velocities, such as those found in detonics experiments. The Photonic Doppler Velocimeter (PDV) can be visualized as a fiber-based Michelson interferometer. The light from a single-mode fiber laser at 1550 nm is passed through a circulator, which acts to separate bi-directional light. The beam is then reflected via free-space optics off the surface of interest, and then focused back into the same fiber. This ...
... It has 2x 15L bins: one for food waste, the other for recycling, which slide out on ball bearing steel runners. Both have plastic inner buckets that can be lifted out. Supplied with fixing brackets. To fit 30cm-wide cabinets Filed Under: Top Products Tagged With: bedroom, bins, drawers, drawersshelveskitchenbins, garden, home, homegardenbedroomstorage, John Lewis, kitchen, shelves, storage ...
In 1996, the National Marine Fisheries Service and the University of Washington completed the fourth year of a multi-year study to estimate survival of juvenile salmonids (Oncorhynchus spp.) passing through dams and reservoirs on the Snake River. Actively migrating smolts were collected near the head of Lower Granite Reservoir and at Lower Granite Dam, tagged with passive integrated transponder (PIT) tags, and released to continue their downstream migration. Individual smolts were subsequently detected at PIT-tag detection facilities at Lower Granite, Little Goose, Lower Monumental, McNary, John Day and Bonneville Dams. Survival estimates were calculated using the Single-Release (SR) and Paired-Release (PR) Models. Timing of releases of tagged hatchery steelhead (O. mykiss) from the head of Lower Granite Reservoir and yearling chinook salmon (O. tshawytscha) from Lower Granite Dam in 1996 spanned the ...
BackgroundPlasmid encoded blaCTX-M enzymes represent an important sub-group of class A β-lactamases causing the ESBL phenotype which is increasingly...Full Text Available
The aim of this study was to compare a 1-day with a 2-day iodine bowel preparation for CT colonography in a positive faecal occult blood test (FOBT) screening population. One hundred consecutive patients underwent CT colonography and colonoscopy with segmental unblinding. The first 50 patients (group 1) ingested 7*50 ml iodinated contrast starting 2 days before CT colonography. The latter 50 patients (group 2) ingested 4*50 ml iodinated contrast starting 1 day before CT colonography. Per colonic segment measurements of residual stool attenuation and homogeneity were performed, and a subjective evaluation of tagging quality (grade 1-5) was done. Independently, two reviewers performed polyp and carcinoma detection. The tagging density was 638 and 618 HU (p = 0.458) and homogeneity 91 and 86 HU for groups 1 and 2, respectively (p = 0.145). The tagging quality was graded 5 (excellent) in 90% of all segments in group 1 and 91% ...
We theoretically investigate the features of two-photon absorption in a coherently driven four-level atomic system with closed-loop configuration. It is found that two-photon absorption can be completely suppressed just by properly adjusting the relative phase of four coherent low-intensity driving fields and the atomic system becomes transparent against two-photon absorption. From a physical point of view, we explicitly explain these results in terms of quantum interference induced by two different two-photon excitation channels.
We discuss elastic electron-deuteron (ed) scattering beyond the Born approximation. The reaction amplitude contains six generalized form factors, but only three linearly independent combinations of them (generalized charge, quadrupole, and magnetic form factors) contribute to the reaction cross section in second-order perturbation theory. We examine the two-photon exchange and find that it includes two types of diagrams, where two virtual photons are interacting with the same nucleon and where the photons are interacting with different nucleons. It is shown that the two-photon-exchange amplitude is strongly connected with the deuteron wave function at short distances.
In the convolution/superposition algorithm, the energy spectrum should be modified to make the reconstructed dose distribution consistent with the measured dose distribution. The energy spectrum, which gives the best agreement, is not determined uniquely depending on the reconstruction procedure. In this report, the effects of the characteristics of the energy spectrum on the calculation accuracy are evaluated by comparing the percentage depth dose (PDD) and beam profiles for the reference energy spectrum with those calculated for the modified spectrum in order to optimize the energy spectrum modification procedure when 4 and 10 MV X-ray beams are used. Decreasing the number of energy bins brought a larger decrease rate in the computation accuracy than a decrease rate in computation time. Further, the decrease of the number of energy bins led to a change of the energy spectrum. The balance of the relative fluence weight in a each bin and its ...
The Anisotropic Analytical Algorithm (AAA) is a new pencil beam convolution/superposition algorithm proposed by Varian for photon dose calculations. The configuration of AAA depends on linear accelerator design and specifications. The purpose of this study was to investigate the accuracy of AAA for an Elekta SL25 linear accelerator for small fields and intensity modulated radiation therapy (IMRT) treatments in inhomogeneous media. The accuracy of AAA was evaluated in two studies. First, AAA was compared both with Monte Carlo (MC) and the measurements in an inhomogeneous phantom simulating lung equivalent tissues and bone ribs. The algorithm was tested under lateral electronic disequilibrium conditions, using small fields (2x2 cm"2). Good agreement was generally achieved for depth dose and profiles, with deviations generally below 3% in lung inhomogeneities and below 5% at interfaces. However, the effects of attenuation and scattering close to ...
We have constructed a Monte Carlo generator (the corresponding FORTRAN code can be obtained from the authors upon request) for lowest-order predictions for the processes {gamma}{gamma}{yields}4f and {gamma}{gamma}{yields}4f{gamma} in the standard model and extensions thereof by an effective {gamma}{gamma}H coupling as well as anomalous triple and quartic gauge-boson couplings. Polarization is fully supported, and a realistic photonbeam spectrum can be taken into account. For the processes {gamma}{gamma}{yields}4f all helicity amplitudes are explicitly given in a compact form. The presented numerical results contain, in particular, a survey of cross sections for representative final states and their comparison to results obtained with the program package Whizard/Madgraph. The impact of a realistic beam spectrum on cross sections and distributions is illustrated. Moreover, the size of various contributions to cross sections, ...
We have constructed a Monte Carlo generator (the corresponding FORTRAN code can be obtained from the authors upon request) for lowest-order predictions for the processes #gamma##gamma##->#4f and #gamma##gamma##->#4f#gamma# in the standard model and extensions thereof by an effective #gamma##gamma#H coupling as well as anomalous triple and quartic gauge-boson couplings. Polarization is fully supported, and a realistic photonbeam spectrum can be taken into account. For the processes #gamma##gamma##->#4f all helicity amplitudes are explicitly given in a compact form. The presented numerical results contain, in particular, a survey of cross sections for representative final states and their comparison to results obtained with the program package Whizard/Madgraph. The impact of a realistic beam spectrum on cross sections and distributions is illustrated. Moreover, the size of various contributions to cross sections, ...
The purpose of this study is to evaluate the accuracy of dose calculations by three algorithms. Depth dose, OPF (Output Factor) and dose profiles were measured in a heterogeneous phantom. These values were also calculated by three algorithms of the Batho power law (BPL), Equivalent-Tissue Air Ratio (ETAR) and Convolution superposition (CS). The data were obtained for 4, 6 and 10 MV photonbeams with a linear accelerator (Varian 21EX). Field size ranged from 3 x 3 cm"2 to 10 x 10 cm"2. Dose profiles of beam penumbra were also measured by a 0.125 ml ionization chamber at the point of 8, 13 and 18 cm from the surface of the phantom at intervals of 1 mm. Differences between measured and calculated depth doses were within 2% in BPL and CS, but depth doses were overestimated in ETAR. OPFs were also overestimated with the error of more than 4% in ETAR. Absorbed dose calculated by CS were in agreement with the values measured by ...
For heavy-ion beam driven inertial fusion ''liquid-protected'' reactor designs such as HYLIFE-II, a mixture of molten salts made of F{sup 10}, Li{sup -6}, Li{sup 7} and Be{sup 9} (called flibe) allows small chambers and final-focus magnets closer to the target with superconducting coils suffering higher radiation damage, though they can stand only a certain amount of energy deposited before quenching. This work has been primarily focusing on verifying that total energy deposited by fusion neutrons and induced gamma rays remain under such limit values and the final purpose is the optimization of the shielding of the magnetic lens system from the points of view of the geometrical configuration and of the physical nature of the materials adopted. The system is analyzed in terms of six geometrical models going from simplified up to much more realistic representations of a system of 192 beam lines, each focused by ...
The accuracy of dose computation within the lungs depends strongly on the performance of the calculation algorithm in regions of electronic disequilibrium that arise near tissue inhomogeneities with large density variations. There is a lack of data evaluating the performance of highly developed analytical dose calculation algorithms compared to Monte Carlo computations in a clinical setting. We compared full Monte Carlo calculations (performed by our Monte Carlo dose engine MCDE) with two different commercial convolution/superposition (CS) implementations (Pinnacle-CS and Helax-TMS's collapsed cone model Helax-CC) and one pencil beam algorithm (Helax-TMS's pencil beam model Helax-PB) for 10 intensity modulated radiation therapy (IMRT) lung cancer patients. Treatment plans were created for two photonbeam qualities (6 and 18 MV). For each dose calculation algorithm, patient, and beam ...
We consider the electron-positron pair creation by a photon in an external constant electric field. The presented treatment is based on a purely quasiclassical calculation of the imaginary part of the on-shell photon polarization operator. By using this approach we find the pair production rate for photons with polarization parallel as well as orthogonal to the external electric field in the leading order in the parameter eE/m"2, which has been recently found by other methods. For the orthogonal polarization we also find a new contribution to the rate, which is leading in the ratio of the photon energy to the electron mass #omega#/m. We also reproduce by a purely geometrical calculation the exponential factor in the probability of the stimulated pair creation at arbitrary energy of the photon.
The generation and control of quantum states of light constitute fundamental tasks in cavity quantum electrodynamics (QED). The superconducting realization of cavity QED, circuit QED, enables on-chip microwave photonics, where superconducting qubits control and measure individual photon states. A long-standing issue in cavity QED is the coherent transfer of photons between two or more resonators. Here, we use circuit QED to implement a three-resonator architecture on a single chip, where the resonators are interconnected by two superconducting phase qubits. We use this circuit to shuffle one- and two-photon Fock states between the three resonators, and demonstrate qubit-mediated vacuum Rabi swaps between two resonators. This illustrates the potential for using multi-resonator circuits as photon quantum registries and for creating multipartite entanglement between delocalized bosonic ...
Transport of negative ion beams through plasma is reviewed. The effect of space charge on beam stability and beam emittance is discussed. The approaches to the beam transport problem developed at Los Alamos, Berkeley, Oak Ridge and Culham Laboratory are intercompared. (AIP)
This thesis describes the analysis of the semileptonic decay D{sup 0} {yields} {bar K}{sup 0} {pi}{sup -} {mu}{sup +}{nu} using FOCUS data. FOCUS is a fixed target experiment at Fermilab that studies the physics of the charm quark. Particles containing charm are produced by photon-gluon fusion from the collision of a photonbeam on a BeO target. The experiment is characterized by excellent vertex resolution and particle identification. The spectrometer consists of three systems for track reconstruction (two silicon systems and one multiwire proportional chamber system) and two magnets of opposite polarity. The polarity of the magnet is such that the events of e{sup +}e{sup -} pairs produced in the target (which constitutes the main background) travel through a central opening in the detectors without interactions. Particle momentum is measured from the deflection angle in the magnets. Three multicell Cerenkov counters are ...
A scheme is presented for the generation of entangled states for two cavity mirrors. In the scheme each mirror initially in a vacuum state interacts with a weak coherent field, resulting in a photon-number dependent kick. The detection of a photon leaking from the cavities collapses the two mirrors to an entangled state.
The present status of theoretical description of deep-inelastic lepton-nucleon as well as large angle Bhabha scattering with account for radiative corrections in the leading and next-to-leading approximations are reviewed. Also considered is a build-up principle and physical programme of the photon-photon colliders
... Biomedical Engineering Optical and Photonic Materials and Devices Fundamental Optical Interactions ... of Texas Medical School OPTICAL AND PHOTONIC MATERIALS AND DEVICES Gary Bjorklund, IBM, Chair Nan ...
Beamline VI is a wiggler-based, multi-kilowatt, intense synchrotron radiation beamline installed SPEAR. The thermal design parameters for this beamline are presented and then design considerations and construction descriptions are given for many of the high-power photon beamline elements.
Complete factorization scheme analysis of $F_2^{\\gamma}(x,Q^2)$ in the next--to--leading order QCD is performed. It is shown that the presence of the inhomogenous term in the evolution equations for parton distribution functions of the photon implies qualitative change in the way factorization mechanism works in photon--hadron and photon--photon collisions as compared to hadron--hadron ones. The incompletness of the existing NLO analyses of $F_2^{\\gamma}(x,Q^2)$ is pointed out and its origins traced back to the misinterpretation of the behaviour of $q^{\\gamma}(x,M)$ as a function of in the LO photonic coefficient function $C_{\\gamma}^{(0)}(x)$ is given and smooth transition between the properties of virtual and real photon discussed. A simple way of avoiding the problems with the term $\\ln(1-x)$ appearing in the standard expression for $C_{\\gamma}^{(0)}(x)$ in the case of the ...
Various physico-chemical tissue optical clearing (TOC) methods have been suggested to maximize photon density in tissue. In order to enhance photon density, a compression-controlled low-level...Full Text Available
The utility of a two-photon optical fiber fluorescence probe (TPOFF) for sensing and quantifying tumor fluorescent signals was tested in vivo. Xenograft tumors were developed in athymic mice using MCA207...Full Text Available
We present a measurement of the t{bar t} production cross section using events with one charged lepton and jets from p{bar p} collisions at a center-of-mass energy of 1.96TeV. In these events, heavy flavor quarks from top quark decay are identified with a secondary vertex tagging algorithm. From 162 pb{sup -1} of data collected by the Collider Detector at Fermilab, a total of 48 candidate events are selected, where 13.5 {+-} 1.8 events are expected from background contributions. We measure a t{bar t} production cross section of 5.6{sub -1.1}{sup _1.2}(stat.){sub -0.6}{sup +0.9}(syst.)pb.
The LHCb experiment that is being settled in CERN is dedicated to the study of CP violation and rare decays in the field of beauty hadrons. The phenomenological background necessary to an adequate understanding of the physics of flavor is presented in the first chapter, it is shown how the flavordynamics can open the way to new physics. The second chapter is dedicated to a brief presentation of the LHCb detector. Two aspects of the design of the muon trigger are more detailed: the radiation resistance of the opto-electronic transmitters and the simulated performances of the trigger. The third chapter reviews the tasks linked to the tagging of the savors of B mesons which will be an important step in all the experiments made at LHCb. The recent progress in heavy savor physics as well as the expected contribution of LHCb in this field are presented in the fourth chapter, especially the search for new physics in penguin diagrams b {yields} s.
At future {gamma} {gamma} colliders a massive production of tt-bar pairs is possible. This would allow a detailed investigation of the interactions involving the top quark. The authors propose some correlations which are sensitive to tt-bar final state interactions and compute the QCD and standard model Higgs boson contributions to these correlation. QCD-induced transverse polarization of top quarks is found to be sizeable and measurable at a high-energy e{sup +} e{sup -} collider with an integrated luminosity of 10(fb){sup -1} which is converted into a photon collider by backscattering of laser photons. 16 refs.
At future #gamma##gamma# colliders copious production of t bar t pairs is possible. This would allow for a detailed investigation of the interactions involving the top quark. We propose some correlations which are sensitive to t bar t final state interactions and we compute the QCD and standard model Higgs boson contributions to these correlations. A correlation resulting from the QCD induced transverse polarization of top quarks is found to be sizable and measurable at a high energy e"+e"- collider, which is operated as a photon collider through backscattering of laser photons, at an integrated luminosity of 10 fb"-"1.
In this paper we discuss recent work at the Advanced Technology Centre of BAE Systems on photonic technology, in particular photonic crystal fibres, applied to infra-red and electro-optic countermeasure systems. The use of Photonic Crystal fibres or holey fibres in countermeasure systems could significantly simplify platform integration by enabling remote location of laser sources, the generation of multiple wavelengths or continuum generation from a single pump source .The paper will describe the development of these fibres, drawing examples from recent civil collaborative research projects such as PFIDEL and LAMPS.
With the help of self-assembly, thermal sintering, selective etching techniques and sol-gel process, the non-close packed (ncp) face-centered cubic (fcc) photonic crystals of titanium dioxide (TiO2) hollow spheres connected by TiO2 cylindrical tubes have been fabricated using silica template. The photonic bandgap calculations indicate that the ncp structure of TiO2 hollow spheres was easier to open the pseudogaps than close packed system at the lowest energy. PMID:17097102
While bone metastases producing photon deficient defects on bone scintigraphy have previously been reported, this finding has not been emphasized for hepatocellular carcinoma (HCC). Furthermore, ''filling-in'' of such photon deficient defects with 67Ga at skeletal sites of metastatic HCC has not been described. In this case report, the combination of a photon deficient defect on bone scintigraphy and avid accumulation of 67Ga in this same area was of value in confirming the diagnosis of metastatic HCC.
In this project we developed photonic crystal modeling capability and fabrication technology that is scaleable to large area. An intelligent optimization code was developed to find the optimal structure for the desired spectral response. In terms of fabrication, an exhaustive survey of fabrication techniques that would meet the large area requirement was reduced to Deep X-ray Lithography (DXRL) and nano-imprint. Using DXRL, we fabricated a gold logpile photonic crystal in the <100> plane. For the nano-imprint technique, we fabricated a cubic array of gold squares. These two examples also represent two classes of metallic photonic crystal topologies, the connected network and cermet arrangement.
We study a quantum computing system using microwave photons in transmission line resonators on a superconducting chip as qubits. We show that linear optics and other controls necessary for quantum computing can be implemented by coupling to Josephson devices on the same chip. By taking advantage of the strong nonlinearities in Josephson junctions, photonic qubit interactions can be realized. We analyze the gate error rate to demonstrate that our scheme is realistic even for Josephson devices with limited decoherence times. As a conceptually innovative solution based on existing technologies, our scheme provides an integrated and scalable approach to the next key milestone for photonic qubit quantum computing.
... is the sensor that converts incoming photons into a ... with CCD foundries to acquire such a sensor. ... 2007, Journal of Spacecraft and Rockets, 44, 910 ...
... concentrated on the construction of switches using fiber ... been chosen for a switch realized in ... of these techniques using acousto-optic modulators or ...
High-brightness negative ion beams, especially O{sup -} beams, from a compact gaseous plasma source are studied to evaluate the suitability for high-resolution SIMS. Ion-optical calculations are made using the beam parameters from the new source. Results suggest that sub-100 nm spot with O{sup -} beam current of 10 pA is achievable. Beam focusing, the resulting beam current distributions at the target and the expected instrumental performance are discussed.
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Continuum events represent an eminent source of background in any e+e- experiment. As these have a higher branching ratio than BB-bar events (at BaBar this ratio is estimated to about 3.5) or ?+?- events, efficient continuum background suppression is essential in many analyses. Using Artificial Neural Networks and the Nearest Neighbor Method we developed several selectors which, based only on the global event shape variables, efficiently tag BB-bar events and ?+?- events against the continuum background. These selectors could then be combined with the channel specific information in various types of analyses. The study was done using a parametric Monte Carlo.
A general analysis is presented of a photon storage cavity, coupled to free-electron laser (FEL) cavity. It is shown that if the coupling between the FEL cavity and the storage cavity is unidirectional (for example, a ring resonator storage cavity) then storage is possible, but that if the coupling is bi-directional then storage is not possible. Parameters are presented for an infra-red FEL storage cavity giving an order of magnitude increase in the instantaneous photon power within the storage cavity. 4 refs., 3 figs.
Using spectral hole-burning-based ultraslow group velocity in a dilute solid medium, we report enhanced photon echo efficiency three orders of magnitude higher than that in a nonslow light regime. The enhancement is due to exponentially increased absorption of an optical data pulse owing to the enhanced photon-atom interaction in an ultraslow light regime, whereas echo reabsorption is negligibly small due to group-velocity dependent population depletion.
We study the possibility of utilizing the superfluid to Mott-insulator quantum phase transition in an array of quantum well exciton-polariton traps to generate indistinguishable single photons in a massive parallel fashion. By means of analytical and numerical methods, the device operations and system properties are examined using realistic experimental parameters. Such a deterministic, massive parallel generation may find new applications in photonic quantum information processing.
We report the first experimental generation and characterization of a six-photon Dicke state and demonstrate its remarkable versatility by projecting out four- and five-photon Dicke states, in addition to four-photon GHZ- and W-states. These multipartite states are studied by developing experimentally favorable characterization tools. Furthermore, we show that Dicke states have interesting applications in multiparty quantum networking protocols such as open-destination teleportation, telecloning and quantum secret sharing.
The design of the absorber blocks for internal and external dumping of the SPS proton beam is discussed. In addition, the external target stations for slow and fast extracted proton beams are described.
A scheme of evaluating a generalized three-photon excitation cross section #sigma#/sub (3)/ in neutral atomic argon at 3144.67 A is outlined. Three photons at this wavelength can excite the neutral argon atoms from the ground 3p"6 "1S_0 state to the 3p"54s'[1/2]_1"0 state. The fourth photon will ionize the argon atoms. Assuming linear polarization of the incident laser radiation, contributions from several channels in various energy-level schemes are summed in the evaluation of the transition probability. For a laser linewidth of #DELTA##lambda#/sub L/ = 1 A, our maximum numerical value of the computed result for the three-photon excitation cross section is #sigma#/sub (3)/ = 1.414 x 10/sup -80/ cm"6 s"2. .AE.
Details of the interaction of photons with tissue phantoms are elucidated using Monte Carlo simulations. In particular, photon sampling volumes and photon pathlengths are determined for a variety of scattering and absorption parameters. The Monte Carlo simulations are specifically designed to model light delivery and collection geometries relevant to clinical applications of optical biopsy techniques. The Monte Carlo simulations assume that light is delivered and collected by two, nearly-adjacent optical fibers and take into account the numerical aperture of the fibers as well as reflectance and refraction at interfaces between different media. To determine the validity of the Monte Carlo simulations for modeling the interactions between the photons and the tissue phantom in these geometries, the simulations were compared to measurements of aqueous suspensions of polystyrene microspheres in the ...
We report on a two-photon interference experiment in a quantum relay configuration using two picosecond regime PPLN waveguide based sources emitting paired photons at 1550 nm. The results show that the picosecond regime associated with a guided-wave scheme should have important repercussions for quantum relay implementations in real conditions, essential for improving both the working distance and the efficiency of quantum cryptography and networking systems. In contrast to already reported regimes, namely femtosecond and CW, it allows achieving a 99% net visibility two-photon interference while maintaining a high effective photon pair rate using only standard telecom components and detectors.
The specific research goal of this project is to identify means to restore and rebuild the Snake River white sturgeon (Acipenser transmontanus) population to support a sustainable annual subsistence harvest equivalent to 5 kg/ha/yr (CBFWA 1997). Based on data collected, a white sturgeon adaptive management plan will be developed. This 2001 annual report covers the fifth year of sampling of this multi-year study. In 2001 white sturgeon were captured, marked, and population data were collected in the Snake and Salmon rivers. The Snake River was sampled between Lower Granite Dam (rkm 174) and the mouth of the Salmon River (rkm 303), and the Salmon River was sampled from its mouth upstream to Hammer Creek (rkm 84). A total of 45,907 hours of setline effort and 186 hours of hook-and-line effort was employed in 2001. A total of 390 white sturgeon were captured and tagged in the Snake River and 12 in the Salmon River. Since 1997, 36.1 percent of the ...
This work is a theoretical investigation on the physical properties of semiconductor-based two-dimensional photonic crystals, in particular for what concerns systems embedded in planar dielectric waveguides (GaAs/AlGaAs, GaInAsP/InP heterostructures, and self-standing membranes) or based on macro-porous silicon. The photonic-band structure of photonic crystals and photonic-crystal slabs is numerically computed and the associated light-line problem is discussed, which points to the issue of intrinsic out-of-lane diffraction losses for the photonic bands lying above the light line. The photonic states are then classified by the group theory formalism: each mode is related to an irreducible representation of the corresponding small point group. The optical properties are investigated by means of the scattering matrix method, which numerically implements a ...
The construction of networks consisting of optically interconnected processing units is a promising way to scale up quantum information processing systems. To store quantum information, single trapped atoms are among the most proven candidates. By placing them in high finesse optical resonators, a bidirectional information exchange between the atoms and photons becomes possible with, in principle, unit efficiency. Such an interface between stationary and ying qubits constitutes a possible node of a future quantum network. The results presented in this thesis demonstrate the prospects of a quantum interface consisting of a single atom trapped within the mode of a high-finesse optical cavity. In a two-step process, we distribute entanglement between the stored atom and two subsequently emitted single photons. The long atom trapping times achieved in the system together with the high photon collection efficiency of the cavity ...
The total interaction cross sections (#sigma#_t) of some sugars and amino acids and five elements: lithium, carbon, oxygen, aluminium and calcium have been measured for 6.4 keV, 13.95 keV, 14.4 keV, 17.74 keV, 24.14 keV, 30.8 keV, 35 keV, 59.54 keV, 81 keV, 122 keV and 136 keV photons in a narrow beam good geometry set up, by using high resolution detectors such as a Si-PIN diode detector and a high purity germanium detector. The #sigma#_t values have been used in a matrix method to evaluate the effective atomic numbers Z_e_f_f of the samples from their effective atomic cross sections #sigma#_a. The effective atomic cross section of a sample #sigma#_a is the total interaction cross section divided by the total number of atoms of all types in it. Further, a quantity called the effective atomic weight A_e_f_f of a sample was defined as the ratio of the molecular weight A to the total number of atoms of all types in it. The variation of Z_e_f_f ...
This report describes a study of the mass of the electron neutrino using electron capture in {sup 163}Ho in Japan for the period from 1981 to 1994. This monograph has two purposes, one is to supplement the papers on the mass of the electron neutrino already published by us and another is to make a record on some details of our experiments for future. Electron capture in a nucleus takes place in a rather small space inside an atom, where atomic physics, nuclear physics and particle physics work closely together. Therefore, this study needed an intimate collaboration of atomic physicists, nuclear physicists and particle physicists. In addition, it was necessary for this study to use various fine techniques, including metallurgy, production of {sup 163}Ho activity, micro-analysis by wet chemistry, isotope-dilution mass spectrometry, undulator radiation source technology, the soft X-ray monochromator technology, a counting technique for very intense soft X-rays and so on. As a result, our ...
The main goals of nuclear astrophysics have been to probe the interiors of stars, stellar explosions, the early moments of cosmic expansion, and the formation and evolution of galaxies and cosmic structure by measurement and application of the relevant nuclear physics. The approach to these goals have generally been from three directions: 1) Careful measurements of the relevant nuclear reactions; 2) Detailed computer models of the relevant astrophysical environments; and 3) Observations of the relevant terrestrial and extra-terrestrial atomic and isotopic abundances. These approaches provide not only insight into the formation and evolution of the elements, but are also pillars upon which a variety of cosmological models as well as models for physics beyond the standard model of particle physics can stand or fall. At present there is a very exciting frontier on all three of these approaches. The development and applications of radioactive-ion-beam and ...
Microplanar beam radiation therapy has been proposed to treat brain tumors by using a series of rapid exposures to an array of parallel x-ray beams, each beam having uniform microscopic thickness and...Full Text Available
A simple beam-forming system is described for the electrostatic accelerator of the Scientific-Research Institute of Nuclear Physics of Moscow State University. The system allows the beam to be focused on targets at various distances for a conductor potential of from 1 to 4 MV and beam currents of up to 35 #mu# A.
The purpose was to identify human in vitro cell lines with a high relative cellular sensitivity to fast neutrons as compared to photons and to examine their relationship to intrinsic photon radiosensitivity and cellular proliferation kinetics. The clonogenic cell survival following exposure to low LET, 4 MeV photons or, high LET, 62.5 MeV (p #-># Be"+) fast neutrons and the cell survival following exposure to low LET, 4 MeV photons or, high LET, 62.5 MeV (p #-># Be"+) fast neutrons and the cell kinetic parameters of 30 human in vitro cell lines, covering a wide range of histologies, were analyzed alone and with previously published data of Fertil and Malaise. The relative survival at 1.6 Gy of neutrons (SF_1_._6) compared to 2 Gy of photons (SF_2) and the cell kinetic parameters of the 30 cell lines were also compared. The relative lethality of 62.5 MeV fast neutrons was ...
Laser optical pumping can be used to produce polarized alkali atom beams or polarized alkali vapor targets. Polarized alkali atom beams can be converted into polarized alkali ion beams, and polarized alkali vapor targets can be used to produce polarized H/sup -/ or /sup 3/He/sup -/ ion beams. In this paper the authors discuss how the polarized alkali atom beams and polarized alkali vapor targets are used to produce polarized ion beams with emphasis on the production of polarized negative ion beams.
Gallium liquid-metal ion sources that have been introduced in the late 1970s have allowed the development of a new class of micro- and nanofabrication tools collectively denominated as focused ion beam (FIB) machines. To investigate the potential of a helium beam in such a FIB instrument the authors have tested a room-temperature electron beam ion trap coupled with a high resolution FIB machine. In this letter they present their first results in target imaging using a helium beam with a resolution that allows to account for a beam diameter in the submicrometer range.
It is possible to produce energetic beams of radioactive nuclei, as secondary beams, from the heavy-particle compound accelerator called BEVALAC. These beams can be focused into experimental areas without significant contamination using suitable magnetic filters and proper beam-optics. Properly selected high-energy beams of radioactive nuclei (those which defay by positron emission) can provide a truly unique opportunity to evaluate the effectiveness of these beams in localizing the Bragg peak on a tumor volume - necessary in heavy-particle therapy. Preliminary data are presented here to demonstrate the possible use of these beams in radiotherapy treatment-planning verification.
The electron beam ion source (EBIS) at Texas A and M University was constructed and is currently undergoing tests on the injection and transmission of the electron beam through the solenoid. Results of computer simulation of the electron beam are presented, as well as measurements of electron beam profiles using a pinhole beam analyzer.
This paper describes the effects of motion of beam components (quads, rf cavities and dipoles) on the beam and considers the properties of a compensation system from the perspective of users. The system departs from standard practice in considering active perturbation of the electron beam to verify beam corrections. The effects of local closed orbit perturbations to direct undulator beams at different experimental setups are also considered.
Many nondestructive beam position monitors are known. However, these devices can not be used for DC particle beam diagnostics. We investigated a method of beam diagnostics applicable for the operative control of DC high power e-beam inside closed waveguide. A design of the detector for determination of{open_quote} center of mass {close_quote} position of DC particle beam was developed. It was shown that the monitor can be used as a nondestructive method for the beam position control in resonators. Magnetic field of the particle beam outside a resonator is used. The detector consists of the steel yokes and magnetic field sensors. The sensors measure magnetic fluxes in the steel yokes fixed outside the resonator. When the particle beam changes its position, these magnetic fluxes also change. Beam ...
Semiconductor quantum dots (QDs) are a promising approach to realize a single-photon source. To avoid bulky and expensive laser systems for future applications, electrical excitation is desirable. InP QDs are especially suited, as they emit in the red spectral range and therefore in the optimal range of commercial detectors. Additionally, they have been shown to be capable of emitting single photons up to 80 K. Thus, we embedded InP QDs in the intrinsic region of a p-i-n diode. To form single devices, 100 #mu#m mesas were etched and supplied with electrical contacts. We investigated the electroluminescence from single QDs and performed second-order auto correlation measurements to verify single-photon emission. To prevent expensive helium cooling and reach operation above 80 K, we investigated the influence of elevated temperature on the performance of our device. Since triggered single-photon emission ...
The purpose of this study was to determine the optimal technique for delivering postoperative radiotherapy for vulvar cancer and other tumors requiring treatment of the inguinal nodes. This project compared tumor coverage and normal tissue sparing for the 5 main radiotherapy techniques that are used to treat vulvar cancer. The intensity-modulated radiation therapy (IMRT) plan was undesirable because it resulted in an excessive dose to portions of the central pelvic structures. The photon thunderbird with skin match was unacceptable because it underdosed a portion of the groin region. The electron thunderbird was ideal for thin patients but was not applicable for most patients because of excessive dose to the skin and subcutaneous tissues. The photon through-and-through and the photon thunderbird with deep match were acceptable in most situations. In thin patients, where the depth of the inguinal vessels is less than 3 cm, ...
A new kind of e-beam bunching enabling the production of coherent spontaneous emission (CSE) is proposed and considered. It is shown that an e-beam in passing through an undulator will induce CSE along with incoherent spontaneous radiation on the same wavelength if the e-beam transverse velocity is modulated with a spatial period twice as long as the radiation wavelength. Such angular modulated beams can be regarded as alternatives to conventionally density modulated beams for CSE production. Requirements for e-beams are similar in both cases.
Special beam extraction channel is used at INR linac for isotope production. It starts from 160 MeV measuring and matching area of accelerator. This choice of beam extraction enables to direct to the target of isotope complex a proton beam of wide energy range up to 160 MeV. It is important for production of different types of nuclides. The measuring results of proton beam behavior in this region are presented. Required beam forming in 160 MeV measuring and matching area of accelerator and in beam extraction channel is discussed.
The NuMI proton beam at Fermilab currently delivers 120 GeV protons to the neutrino production target with design beam power capability to 400 kW. Upgrade capability to 700 kW is being prepared, with planning toward delivering 2.3 MW beam provided by the Project X accelerator upgrade plan. We report on the system of beam diagnostics and control used in operation of the NuMI beam. Also considered are the steps to provide a robust system for transport and targeting beam of 2 MW and beyond.
Methods and apparatus are described for efficient photodetachment and purification of negative ion beams. A method of purifying an ion beam includes: inputting the ion beam into a gas-filled multipole ion guide, the ion beam including a plurality of ions; increasing a laser-ion interaction time by collisional cooling the plurality of ions using the gas-filled multipole ion guide, the plurality of ions including at least one contaminant; and suppressing the at least one contaminant by selectively removing the at least one contaminant from the ion beam by electron photodetaching at least a portion of the at least one contaminant using a laser beam.
We studied two-photon exchange for elastic electron-proton scattering at low Q{sup 2}. Compact approximate formulas for the amplitudes were obtained. Numerical calculations were done for Q{sup 2}{<=}0.1 GeV{sup 2} with several realistic form factor parametrizations, yielding similar results. They indicate that the corrections to the magnetic form factor can visibly affect the cross-section and proton radii. For low-Q{sup 2} electron-neutron scattering two-photon exchange corrections were shown to be negligibly small00.
Spontaneous emission in photonic crystals with anisotropic three-dimensional dispersion relation is studied. If the upper level is below a characteristic frequency omega(1), or above omega(2), or between omega(1) and omega(2), the radiation is a localized field with a frequency in the band gap, or a propagating field with a frquency in the band, or a diffusion field, respectively. An analytical expression for the Lamb shift is obtained. The Lamb shift for the current case is small compared to that in an ordinary vacuum or in one- or two-dimensional photonic crystals due to lower density of states. PMID:11017227
We propose a scheme of quantum computation with nonlinear quantum optics. Polarization states of photons are used for qubits. Photons with different frequencies represent different qubits. Single qubit rotation operation is implemented through optical elements like the Faraday polarization rotator. Photons are separated into different optical paths, or merged into a single optical path using dichromatic mirrors. The controlled-NOT gate between two qubits is implemented by the proper combination of parametric up and down conversions. This scheme has the following features: (1) No auxiliary qubits are required in the controlled-NOT gate operation; (2) No measurement is required in the course of the computation; (3) It is resource efficient and conceptually simple.
Impurity effects on the photon-assisted spin-polarized transport through armchair carbon nanotubes connected with ferromagnetic leads are investigated theoretically. The impurity induces one resonant state whose position depends on the impurity strength, which can break the electron-hole symmetry. Whether the impurity suppresses or enhances the spin-coherent current depends on the nanotube length. When the microwave fields are applied on the nanotube, additional small side peaks caused by the photon-assisted tunneling are found. With increasing the impurity strength, one new current peak appears under the influence of both the microwave fields and the impurity.
Heavy quark production in $\\gamma\\gamma$ collisions is analyzed within the approach to hard collisions of photons recently proposed by the author. In this approach evaluating the cross section $\\sigma(\\gamma\\gamma\\to Q\\bar{Q})$ in the ``next-to-leading order of QCD'' requires the inclusion of direct photon contributions up to the order $\\alpha^2\\alpha_s^2$, whereas in the standard approach direct photon terms only up to the order $\\alpha^2\\alpha_s$ are taken into account. Phenomenological consequences of this difference are discussed.
We demonstrated that the intensity levels and lifetimes of two-photon autofluorescences (2PAF) in human liver tissues can be exploited to diagnose hepatocellular carcinoma (HCC). Excited by an infrared femtosecond laser, we suppressed the two-photon autofluorescences of most endogenous fluorophores and made red autofluorescences more specific to particular molecules in the cryo-sectioned human livers. Using such fluorescence contrast, we found HCC tissues have reduced levels of 2PAF and longer fluorescence lifetime.
We have made preliminary estimates of charged particles background at the 100x100 GeV Photon Linear Collider with ultimate luminosity. The charged particles background due to electromagnetic processes is located mainly in the small-angle range of the detector. At large angles, the number of background particles is much smaller. Analysis of the background (at least, in the range under consideration) shows that background conditions for the VLEPP-based Photon Linear Collider are better than at the VLEPP electron-positron collider. ((orig.)).
IntroductionBreast cancer is the most diagnosed and second leading cause of cancer deaths in the U.S. female population. An estimated 5 to 10 percent of all breast cancers are inherited, caused by mutations in the breast cancer susceptibility genes (BRCA1/2). As many as 90% of all mutations are nonsense mutations, causing a truncated polypeptide product. A popular and low cost method of mutation detection has been the protein truncation test (PTT), where target regions of BRCA1/2 are PCR amplified, transcribed/translated in a cell-free protein synthesis system and analyzed for truncated polypeptides by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and autoradiography. We previously reported a novel High Throughput Solid-Phase PTT (HTS-PTT) based on an enzyme-linked immunosorbent assay (ELISA) format that eliminates the need for radioactivity, SDS-PAGE and subjective interpretation of the results. Here, we report the next generation HTS-PTT using ...
We present production rates of the two- and three-jet final states for the processes of massive cc/bb quark production in circularly polarized photon-photon collisions, including QCD radiative corrections. Lowest-order cross section, one-loop virtual correction, and gluon emission correction are shown to be of the same order of magnitude for bb quark production at s{sub {gamma}{gamma}} similar 100 GeV. It is shown that the signal from an intermediate mass Higgs boson is observable at a photon-photon collider, though the statistical significance is substantially reduced with respect to the tree-level calculation. ((orig.)).
We present production rates of the two- and three-jet final states for the processes of massive cc/bb quark production in circularly polarized photon-photon collisions, including QCD radiative corrections. Lowest-order cross section, one-loop virtual correction, and gluon emission correction are shown to be of the same order of magnitude for bb quark production at s_#gamma#_#gamma# similar 100 GeV. It is shown that the signal from an intermediate mass Higgs boson is observable at a photon-photon collider, though the statistical significance is substantially reduced with respect to the tree-level calculation. ((orig.)).
We show that, for the high electron currents used in present-day free-electron lasers, spontaneous radiation is distributed according to thermal statistics.
Solid-state single-photon sources have many desirable features that make them attractive for applications in quantum information processing. However, the phase coherence of such devices can be severely compromised by coupling to the solid-state environment. Here, we study the effects of realistic dephasing environments on a pair of solid-state single photon sources in the context of quantum interference effects such as the Hong-Ou-Mandel dip. By means of exact solutions for the non-Markovian dynamics of the sources, we show that the resulting loss of visibility depends crucially on the timing of photon detection events. Our results demonstrate that the effective visibility can be improved via temporal post-selection, and also that time-resolved interference can be a useful probe of the interaction between the emitter and its host environment.
This work represents the results of an experimental investigation of the electromagnetic dissociation of 200 GeV/nucleon {sup 16}O and {sup 32}S ions in nuclear emulsions. Exclusive channels involving charged fragments have been studied as a function of the energy released and, assuming a Weizsaecker-Williams spectrum of virtual photons, there is a good agreement with results for the ({gamma}, p) processes obtained with real photons. However, the rates found for other processes are larger, in particular for the ({gamma}, {alpha}) on both nuclei. The values of the total integrated absorption cross sections are generally larger than those obtained from real photon experiments but the extent of the discrepancy depends strongly upon which photon results are used in the comparison. (orig.).
Leptonic pair production on nuclei ad EMC-effect are discussed within the frames of the flucton model with scaling distortion. Cumulative production of direct photons and leptonic pairs as a test of the model of hard collisions is considered. The results of calculations of massive leptonic pair production cross sections on nucleus fluctons, caculations of the ratio of deuterium and iron structural functions, cross sections of direct photon production on sup(181)Ta nuclei at Esub(p)=400 GeV and cross section of #pi#-meson production in the model of hard collisions are presented. Experimental discovery of direct cumulative photons is concluded to be important for understanding the mechanism of parton hard scattering from nucleus fluctons.
... 4? Program History 5? Center for Advanced Materials and Smart Structures 6? Center for Systems ... Systems 14? Center for Photonic Materials Research 15? Synthesis, Manufacturing and Characterization ...
In this paper an efficient quantum secure direct communication (QSDC) scheme with authentication is presented, which is based on quantum entanglement and polarized single photons. The present protocol uses Einstein-Podolsky-Rosen (EPR) pairs and polarized single photons in batches. A particle of the EPR pairs is retained in the sender's station, and the other is transmitted forth and back between the sender and the receiver, similar to the ``ping-pong'' QSDC protocol. According to the shared information beforehand, these two kinds of quantum states are mixed and then transmitted via a quantum channel. The EPR pairs are used to transmit secret messages and the polarized single photons used for authentication and eavesdropping check. Consequently, because of the dual contributions of the polarized single photons, no classical information is needed. The intrinsic efficiency and total efficiency are both 1 ...
The recent advances in RFID offer vast opportunities for research, development and innovation in agriculture. The aim of this paper is to give readers a comprehensive view of current applications and new possibilities, but also explain the limitations and challenges of this technology. RFID has been used for years in animal identification and tracking, being a common practice in many farms. Also it has been used in the food chain for traceability control. The implementation of sensors in tags, make possible to monitor the cold chain of perishable food products and the development of new applications in fields like environmental monitoring, irrigation, specialty crops and farm machinery. However, it is not all advantages. There are also challenges and limitations that should be faced in the...
Zusammenfassung Hintergrund Endograftimplantationen im oder am Aortenbogen stellen besondere Herausforderungen an die Implantationstechnik und an die mechanischen Eigenschaften von Stentgrafts und ihren Einf?hrungssystemen, bedingt durch die Notwendigkeit, die Prothesen punktgenau abzusetzen und durch die mit der Biegung im Aortenbogen zunehmende Reibungswiderst?nde innerhalb der Einf?hrungssysteme. Die Endograftsysteme der 1. Generation (Talent?, Zenith TX 1?, TAG?) zeigten in dieser Lokalisation technisch bedingte Limitationen. Neue Prothesen Bei den seit 2004 und 2005 verf?gbaren neuen Stentgrafts (E-vita?, Zenith TX 2?, Valiant?, Relay?) sind diese Limitationen weitgehend ?berwunden. Durch technische Verbesserungen von Stentgrafts und Einf?hrungssystemen ist es nun m?glich, auch lange ...
The use of indigenous bacterial root endophytes with biocontrol activity against soil-borne phytopathogens is an environmentally-friendly and ecologically-efficient action within an integrated disease management framework. The earliest steps of olive root colonization by Pseudomonas fluorescens PICF7 and Pseudomonas putida PICP2, effective biocontrol agents (BCAs) against Verticillium wilt of olive (Olea europaea L.) caused by the fungus Verticillium dahliae Kleb., are here described. A gnotobiotic study system using in vitro propagated olive plants, differential fluorescent-protein tagging of bacteria, and confocal laser scanning microscopy analysis have been successfully used to examine olive roots?Pseudomonas spp. interactions at the single-cell level. In vivo simultaneous visualization...
Summary: Protein features are often displayed along the linear sequence of amino acids that make up that protein, but in reality these features occupy a position in the folded proteins 3D space. Mapping sequence features to known or predicted protein structures is useful when trying to deduce the function of those features and when evaluating sequence or structural predictions. To facilitate this goal, we developed PDBpaint, a simple tool that displays protein sequence features gathered from bioinformatics resources on top of protein structures, which are displayed in an interactive window (using the Jmol Java viewer). PDBpaint can be used either with existing protein structures or with novel structures provided by the user. The current version of PDBpaint allows the visualization of annot...
This paper describes the Knowledge Encapsulation Framework (KEF), a suite of tools to enable knowledge inputs (relevant, domain-specific facts) to modeling and simulation projects, as well as other domains that require effective collaborative workspaces for knowledge-based task. This framework can be used to capture evidence (e.g., trusted material such as journal articles and government reports), discover new evidence (covering both trusted and social media), enable discussions surrounding domain-specific topics and provide automatically generated semantic annotations for improved corpus investigation. The current KEF implementation is presented within a wiki environment, providing a simple but powerful collaborative space for team members to review, annotate, discuss and align evidence with their modeling frameworks. The novelty in this approach lies in the combination of automatically tagged and user-vetted resources, which increases user trust in the ...
A nanosuspension of magnetically tagged metronidazole was developed by the solvent displacement method coupled with ultrasonication and was evaluated for its physicochemical properties. The drug release from metronidazole magnetic nanosuspension at pH 1.2 and 7.0 shows maximum correlation coefficient for zero order and Higuchi model, respectively. The anthelmintic activity of the formulated metronidazole magnetic nanosuspension was evaluated on Indian earthworms (Pheretima poi). Metronidazole magnetic nanosuspension at a dose of 10 and 50 mg/ml shortened by 31% and 34%, respectively, the mean time to death of the earthworms when compared against a non-magnetic metronidazole suspension. Thus, the developed metronidazole magnetic nanosuspension showed potent, controlled and targeted drug action and might be a good therapeutic avenue in combating infectious GI disorders.
The specific research goal of this project is to identify means to restore and rebuild the Snake River white sturgeon (Acipenser transmontanus) population to support a sustainable annual subsistence harvest equivalent to 5 kg/ha/yr (CBFWA 1997). Based on data collected, a white sturgeon adaptive management plan will be developed. This 2000 annual report covers the fourth year of sampling of this multi-year study. In 2000 white sturgeon were captured, marked, and population data were collected in the Snake and Salmon rivers. The Snake River was sampled between Lower Granite Dam (rkm 174) and the mouth of the Salmon River (rkm 303), and the Salmon River was sampled from its mouth upstream to Hammer Creek (rkm 84). A total of 53,277 hours of setline effort and 630 hours of hook-and-line effort was employed in 2000. A total of 538 white sturgeon were captured and tagged in the Snake River and 25 in the Salmon River. Since 1997, 32.8 percent of the ...
The specific research goal of this project is to identify means to restore and rebuild the Snake River white sturgeon (Acipenser transmontanus) population to support a sustainable annual subsistence harvest equivalent to 5 kg/ha/yr (CBFWA 1997). Based on data collected, a white sturgeon adaptive management plan will be developed. This report presents a summary of results from the 1997-2002 Phase II data collection and represents the end of phase II. From 1997 to 2001 white sturgeon were captured, marked, and population data were collected in the Snake and Salmon. A total of 1,785 white sturgeon were captured and tagged in the Snake River and 77 in the Salmon River. Since 1997, 25.8 percent of the tagged white sturgeon have been recaptured. Relative density of white sturgeon was highest in the free-flowing segment of the Snake River, with reduced densities of fish in Lower Granite Reservoir, and low densities the Salmon River. Differences were ...
The biota of the Mississippi River in an ecological recovery zone near Red Wing, MN was studied before and after start-up of a nuclear plant to acquire baseline data and to estimate changes due to thermal addition. Thermal addition produced significant decreases in primary production in a plant region during summer month periods when water temperatures were near 36C. Extensive fisheries studies and sonar tagging/tracking of S. vitreum were performed. Comparison of fisheries results with other riverine, lake, and pond studies indicated a favorable environment for the success of the fish species studied. Qualitative macroinvertebrate surveys were conducted.
Abstract Question: How do the diversity, size structure, and spatial pattern of woody species in a temperate (Mediterranean climate) forest compare to temperate and tropical forests? Location: Mixed evergreen coastal forest in the Santa Cruz Mountains, California, USA. Methods: We mapped, tagged, identified, and measured all woody stems (?1 cm diameter) in a 6-ha forest plot, following Center for Tropical Forest Science protocols. We compared patterns to those found in 14 tropical and 12 temperate forest plots. Results: The forest is dominated by Douglas-fir (Pseudotsuga menziesii) and three species of Fagaceae (Quercus agrifolia, Q. parvula var. shrevei, and Lithocarpus densiflorus), and includes 31 woody species and 8180 individuals. Much of the diversity was in small-diameter shrubs,...
SNAP25 occurs on chromosome 20p12.2, which has been linked to schizophrenia in some samples, and recently linked to latent classes of psychotic illness in our sample. SNAP25 is crucial to synaptic functioning, may be involved in axonal growth and dendritic sprouting, and its expression may be decreased in schizophrenia. We genotyped 18 haplotype-tagging SNPs in SNAP25 in a sample of 270 Irish high-density families. Single marker and haplotype analyses were performed in FBAT and PDT. We adjusted for multiple testing by computing q values. Association was followed up in an independent sample of 657 cases and 411 controls. We tested for allelic effects on the clinical phenotype by using the method of sequential addition and 5 factor-derived scores of the OPCRIT. Nine of 18 SNPs had P values <...
To study interactions between plants and plant-parasitic nematodes, several omics studies have nowadays become extremely useful. Since most data available so far is derived from sedentary nematodes, we decided to improve the knowledge on migratory nematodes by studying the transcriptome of the nematode Pratylenchus coffeae through generating expressed sequence tags (ESTs) on a 454 sequencing platform. In this manuscript we present the generation, assembly and annotation of over 325,000 reads from P. coffeae. After assembling these reads, 56,325 contigs and singletons with an average length of 353bp were selected for further analyses. Homology searches revealed that 25% of these sequences had significant matches to the Swiss-prot/trEMBL database and 29% had significant matches in nematode E...
The effect of Kerr nonlinearity on an Airy beam is investigated by using the nonlinear Schroedinger equation. Based on the moments method, the evolution of the Airy beam width in the rms sense is analytically described. Numerical simulations indicate that the central parts of the major lobe of the Airy beam initially give rise to radial compression during propagation in a focusing medium, even though the rms beam width broadens. The partial collapse of the center parts of the major lobe of the beam appear below the threshold for a global collapse. The evolutions of the field distributions of the Airy beams are different during propagation in different Kerr media while the beams still travel along the parabolic trajectory just as the beam propagates in free space.
To suppress space charge blowup in an ion beam passing through a photoneutralizer, it is necessary to introduce some background gas. An analysis is presented of the neutralization of a high-energy, >200-keV negative deuterium ion beam, exposed to photodetachment while in the presence of deuterium. With a gas thickness of <0.01 Torr.cm, the neutral fraction in the output beam is found to be about the same as that gotten from the photoneutralizer operating in vacuum. Neutral atom beam injection for plasma heating is discussed.
A discussion is presented of the 750-KeV chopper experience with both proton and negative ion beams and the ability of these systems to tailor the Linac beam to the diverse requirements of its users; normal accelerator injection, neutron therapy beam, and electron cooling experiments. This flexibility plus a cleaner beam pulse, improved thyratron operation, and mechanical modularity are the results of recent improvements. Additional benefits have been increased reliability and ease of service to the 750-KeV chopper. 3 refs.
An electron accelerator unit is described for electron beam therapy, comprising: a source of an electron beam; means for finally directing at least a portion of the beam to a therapy site, the directing means being mechanically independent of, and electrically isolated from, the source, and having a target area; and means for aligning the source with the directing means, the aligning means comprising means for projecting at least one beam of light from the source toward the target area.
An electron accelerator unit is described for electron beam therapy, comprising: a source of an electron beam; means for finally directing at least a portion of the beam to a therapy site, the directing means being mechanically independent of, and electrically isolated from, the source, and having a target area; and means for aligning the source with the directing means, the aligning means comprising means for projecting at least one beam of light from the source toward the target area.
Design of a beam position monitor (BPM) which is sensitive to low velo charged particle beams is considered. Quantitative estimates are made for the corrections to the conventional approximations to solutions of the Laplace Equation in two-dimensions when a BPM is used to measure to position of low velocity (low-[beta]) beams. (AIP)
Optical frequency comb technology has been used in this work for the first time to investigate the nuclear structure of light radioactive isotopes. Therefore, three laser systems were stabilized with different techniques to accurately known optical frequencies and used in two specialized experiments. Absolute transition frequency measurements of lithium and beryllium isotopes were performed with accuracy on the order of 10{sup -10}. Such a high accuracy is required for the light elements since the nuclear volume effect has only a 10{sup -9} contribution to the total transition frequency. For beryllium, the isotope shift was determined with an accuracy that is sufficient to extract information about the proton distribution inside the nucleus. A Doppler-free two-photon spectroscopy on the stable lithium isotopes {sup 6,7}Li was performed in order to determine the absolute frequency of the 2S {yields} 3S transition. The achieved relative accuracy of 2 x 10{sup -10} is ...
Thirty-seven patients with primary nonresectable intrahepatic cholangiocarcinoma (57% with prior treatment and/or metastasis) were prospectively treated with external radiation, chemotherapy, and "1"3"1I labelled anti-CEA. Therapy began in all trials with whole liver irradiation (21.0 Gy, 3.0 Gy/Fx, 4 days/week, 10 MV photons) with alternate treatment day chemotherapy (Adriamycin, 15 mg + 5-FU, 500 mg). One month after external beam therapy, chemotherapy was given (Adriamycin, 15 mg + 5-FU, 500 mg) followed the next day by the first administration of "1"3"1I anti-CEA. The treatment schedule used was 20 mCi day 0; 10 mCi day 5 as an outpatient. This schedule was derived from tumor dose estimates which indicated that 20 mCi (8-10 mCi/mg IgG) was sufficient to achieve tumor saturation with a tumor effective half-life of 3 to 5 days, depending upon the species of animal from which the antibody was obtained. The median tumor dose for the 20 mCi + 10 ...
Single photon emission computed tomography (SPECT) of lung perfusions permits to map functioning lung parenchyma with higher sensitivity than CT. Delivering higher radiations doses it used to increase local control in lung carcinoma; this strategy is based on radiobiological and clinical studies. Lung parenchyma is a dose-limiting tissue in patients irradiated for lung cancer. Functional mapping based on SPECT and CT findings permits to design radiation beams such as to minimize irradiation of functioning lung. [Italian] L'integrazione delle immagini diagnostiche aventi diverso contenuto informativo anatomico-funzionale puo' essere utilizzata nella radioterapia per migliorare le procedure diagnostiche e ottimizzare la geometria dell'irraggiamento. I sistemi per l'elaborazione di piani di radioterapia oggi in uso sono direttamente interfacciati con gli apparecchi di Tomografia Computerizzata (TC) e ...
High-energy ionizing radiation is a prominent modality for the treatment of many cancers. The approaches to electron dose calculation can be categorized into semi-empirical models (e.g. Fermi-Eyges, convolution-superposition) and probabilistic methods (e.g. Monte Carlo). A third approach to dose calculation has only recently attracted attention in the medical physics community. This approach is based on the deterministic kinetic equations of radiative transfer. We derive a macroscopic partial differential equation model for electron transport in tissue. This model involves an angular closure in the phase space. It is exact for the free streaming and the isotropic regime. We solve it numerically by a newly developed HLLC scheme based on Berthon et al (2007 J. Sci. Comput. 31 347-89) that exactly preserves the key properties of the analytical solution on the discrete level. We discuss several test cases taken from the medical physics literature. A test case with an academic ...
BackgroundIntrafractional motion results in local over- and under-dosage in particle therapy with a scanned beam. Scanned beam delivery offers the possibility to compensate target...Full Text Available
The performance of the PSI/ETH focused ion beam (FIB) system has been improved to produce ion beams of very low energies down to 40 eV with a reasonable spot size of 1 {mu}m at 200 eV. (author) 2 figs., 1 ref.
The longitudinal and transverse dynamics of a heavy ion fusion beam during the drift compression and final focus phase is studied. A lattice design with four time-dependent magnets is described that focuses the entire beam pulse onto a single focal point with the same spot size.
The issue of beam-induced damage on diffractive hard X-ray optics is addressed. For this purpose a systematic study on the radiation damage induced by a high-power X-ray beam is carried out in both...Full Text Available
L_#alpha#/L_l X-ray intensity ratios have been measured in elements Ta, W, Au, Hg, Tl, Pb, Bi, Th and U using L-shell photoionization by 60 keV photons. The present results are found to agree with the calculated values of Scofield within experimental uncertainties. (author).
By using the quark-parton-flucton and Weinberg-Salam models, effects of interactions of weak neutral quark and neutrino currents were considered in deep - inelastic neutrino (anti)-nucleus scattering #nu# (anti-#nu#) A #-># #nu# (anti-#nu#) #gamma#X. The energy spectrum and degree of photon circular polarization were obtained in present paper. In particular for the nucleon (A = 1). The theoretical results were in a good agreement with data mentioned. (author). 6 refs., 4 figs.
By the methods of the angular distribution of photon annihilation, time distribution of photon annihilation, photoluminescence spectroscopy, Fourier IR-spectroscopy, atomic force microscopy the detail information on relation of the structural and physical properties of the porous nano-structures is obtained. Study of pores sizes in a different nano-porous materials, such as the porous silicon, porous anode aluminium oxide, porous solids exposed to light atoms ion implantation (hydrogen, deuterium, helium) is carried out.
We present a thorough analysis of single atom detection using optical cavities. The large set of parameters that influence the signal-to-noise ratio for cavity detection is considered, with an emphasis on detunings, probe power, cavity finesse and photon detection schemes. Real device operating restrictions for single photon counting modules and standard photodiodes are included in our discussion, with heterodyne detection emerging as the clearly favourable technique, particularly for detuned detection at high power.
The heavy neutral Higgs bosons H, A in the minimal supersymmetric extension of the standard model can be produced as single resonances at high-energy #gamma##gamma# colliders. We have studied the prospects of the search for these particles in bb and neutralino-pair final states. The Higgs bosons can be found with masses up to 70-80% of the initial e"#+-#e"- collider energy for medium values of tg#beta#, i.e. in areas of the supersymmetric parameter space not accessible at other colliders. (orig.)
The proliferation of 'botnets,' phishing schemes, denial-of-service attacks, root kits, and other cyber attack schemes designed to capture a system or network creates a climate of concern for system administrators, especially for those managing accelerator and large experimental-physics facilities, as they are very public targets. This paper will describe the steps being taken at the Advanced Photon Source (APS) to protect the infrastructure of the overall network with emphasis on security for the APS control system.
The electroweak-symmetry-breaking sector of the standard model can be weakly-coupled or can be strongly-coupled, which is characterized by some kinds of strong interaction among the Goldstone bosons of the electroweak-symmetry-breaking sector. In this paper, we summarize an investigation of probing the strong electroweak-symmetry-breaking effects at photon colliders. ((orig.)).
The electroweak-symmetry-breaking sector of the standard model can be weakly-coupled or can be strongly-coupled, which is characterized by some kinds of strong interaction among the Goldstone bosons of the electroweak-symmetry-breaking sector. In this paper, we summarize an investigation of probing the strong electroweak-symmetry-breaking effects at photon colliders. ((orig.)).
The total radiation rate, angular distribution of the emitted energy and photon correlations of the cooperative spontaneous radiation from two atoms with different resonance frequencies and spontaneous decay rates are calculated. Contrary to the case of two identical atoms oscillations appear in the total radiation rate and the spatial distribution of the total number of emitted photons differs from the single-atom radiation pattern. The effect of the dipole-dipole near-field interaction on the time evolution of the atomic system is discussed. (author).
In this small review, the following general properties of the Compton scattering as the basic process for creating {gamma}{gamma} colliders in the scheme suggested in Ginzburg et al. (Inst. Nucl. Phys. 34 (1981) 514; Nucl. Instr. and Meth. 205 (1983) 47) are considered: kinematics, photon spectrum, angular distribution, polarization of the final photons and electrons as well as some related problems.
We derive the expression for spontaneous emission rate in finite one-dimensional photonic crystal with arbitrary defects using the effective resonator model to describe electromagnetic field distributions in the structure. We obtain explicit formulas for contributions of different types of modes, i.e. radiation, substrate and guided modes. Formal calculations are illustrated with a few numerical examples, which demonstrate that the application of effective resonator model simplifies interpretation of results.
A method for conditioning electron beams is proposed, making use of the TM{sub 210} mode of microwave cavities, to reduce the axial velocity spread within the beam, in order to enhance gain in resonant electron beam devices, such as the free-electron laser (FEL). Effectively, a conditioner removes the restriction on beam emittance. The conditioner is analyzed using a simple model for beam transport and ideal RF cavities. Analysis of an FEL is employed to evaluate performance with reduced axial velocity spread. Examples of FELs are presented showing the distinct advantage of conditioning.
The production of polarized negative ion beams by collisional pumping is described. Collisional pumping utilizes repeated charge changing collisions in a thick electron-spin-polarized gas or vapor target to form a polarized fast atom beam. The polarized fast atom beam is then partially converted into a polarized negative ion beam in a vapor target. Analysis is presented for a hydrogen beam passing through either a thick polarized H atom target or a thick polarized alkali target. Large polarizations and large currents may be possible.
The production of polarized negative ion beams by ''collisional pumping'' is described. Collisional pumping utilizes repeated charge changing collisions in a thick electron-spin-polarized gas or vapor target to form a polarized fast atom beam. The polarized fast atom beam is then partially converted into a polarized negative ion beam in a vapor target. Analysis is presented for a hydrogen beam passing through either a thick polarized H atom target or a thick polarized alkali target. Large polarizations and large currents may be possible.
This book is a compliation and analysis of discussions of phenomena important to ion beams and high perveance ion beams. This text discusses physics essential to research on ion beam generation and propagation and provides some requisite background to understanding the criteria for designing electrodes. Ion sources are categorized in terms of their configurations, and the relationships between various types of sources is developed. Covers collisionless space charge phenomena, collisionless plasmas, collisional effects and the taxonomy of high poissance beams. Chapters also treat the field of intense negative ion beams.
The requirements for transporting high-current, negative-ion beams are presented with particular emphasis on applications involving negative-hydrogen-ion beams. In addition to the usual matching and steering problems, particular attention must be paid to beam emittance growth in the transport system. Depending on the application, a number of approaches have been developed using both magnetic and electric lenses. I discuss the design considerations for transporting and matching these beams to radiofrequency quadrupole accelerators, and present a survey of the various types of beamlines now used for negative-ion beams.
The requirements for transporting high-current, negative-ion beams are presented with particular emphasis on applications involving negative-hydrogen-ion beams. In addition to the usual matching and steering problems, particular attention must be paid to beam emittance growth in the transport system. Depending on the application, a number of approaches have been developed using both magnetic and electric lenses. I discuss the design considerations for transporting and matching these beams to radio-frequency quadrupole accelerators, and present a survey of the various types of beamlines now used for negative-ion beams.
The requirements for transporting high-current, negative-ion beams are presented with particular emphasis on applications involving negative-hydrogen-ion beams. In addition to the usual matching and steering problems, particular attention must be paid to beam emittance growth in the transport system. Depending on the application, a number of approaches have been developed using both magnetic and electric lenses. I discuss the design considerations for transporting and matching these beams to radiofrequency quadrupole accelerators, and present a survey of the various types of beamlines now used for negative-ion beams.
An experimental realization of the focusing of an atomic beam by a spontaneous radiation pressure force is reported. A simple light field configuration for focusing an atomic beam is described which is formed by four divergent Gaussian laser beams propagating along the + or - x and + or - y directions of a Cartesian coordinate system. An experimental arrangement for the laser focusing is shown, and the experimental procedure is described. The resulting atomic beam profiles are shown and discussed. It is concluded that the experiments open up the possibility of gaining control over such parameters of atomic beams as their density and divergence. 7 references.
An electrostatic beam steering mechanism (ESM) has been designed and tested to deflect negative ion beams consisting of multi-beamlets. A steering angle of 10 mrad was obtained within the deviation of less than 1 mrad by biasing two electrodes at 0.5 kV and -0.75 kV for 120 keV H{sup -} ion beam. The current flowing to the positive electrode was no more than 10% of the beam current at a pressure of 2.8x10{sup -5} Torr. (author)
A chemically assisted micro-beam etching system for 3D microanalysis was designed. Using chemically assisted ion beam etching (CAIBE) method with FIB shave-off scanning, about several hundred micrometers clean cross-section will be acquired in a few hours. We use focused ion beam (FIB) and electron beam (EB) as micro-beams, halogen or halide mainly as reactive gases. The apparatus was manufactured based on this concept. We found that the FIB, Q-MS and SED worked as expected. The instrumentation has been completed.
The motivation for using a tandem electrostatic accelerator as an electron accelerator for a free electron laser (FEL) is presented. The adaptation of the HVEC EN tandem at the Weizmann Institute for this purpose, electron beam optics and nonlinear FEL computation relevant for this FEL realization are described. In the tandem configuration the terminal is held at a positive potential. The electron beam is accelerated from ground potential to the terminal in one beam tube and then decelerated down the other beam tube. The FEL wiggler and cavity are at the terminal. Due to the beam energy recovery this scheme produces a high power beam at the terminal with a small investment in electrical power. (orig.).
The centroid and envelope dynamics of a high-intensity charged particle beam are investigated as a beam smoothing technique to achieve uniform illumination over a suitably chosen region of the target for applications to ion-beam-driven high energy density physics and heavy ion fusion. The motion of the beam centroid projected onto the target follows a smooth pattern to achieve the desired illumination, for improved stability properties during the beam-target interaction. The centroid dynamics is controlled by an oscillating "wobbler", a set of electrically-biased plates driven by RF voltage. __________________________________________________
A beam position monitoring system has been implemented in the first third of the SLC linac which provides a complete scan of the trajectory on a single beam pulse. The data is collected from the local micro-computers and viewed with an updating display at a console or passed on to application programs. The system must operate with interlaced beams so the scans are also interlaced, providing each user with the ability to select the beam, the update rate, and the attenuation level in the digitizing hardware. In addition each user calibrates the hardware for his beam. A description of the system architecture will be presented. 6 refs., 4 figs.
The development of high energy (> 150 keV) neutral beams for heating and fueling magnetic fusion devices depends on the ability to produce well-collimated negative ion beams. The double capture charge-exchange technique is a known, scalable method. In order to maximize the overall efficiency of the process and to achieve the desired beam characteristics, it is necessary to examine the optical qualities of the beams as well as the total efficiency of beam production. A combined modeling and experimental study of the angular scattering effects in negative ion formation and loss processes has therefore been undertaken.
To achieve high efficiency for the conversion of electron kinetic energy in an electron beam to electromagnetic energy in a Free Electron Laser (FEL), it is important to improve the beam quality. And hence, it is necessary to study and minimize the emittance growth of the beam. According to the requirements for the beam quality in an FEL, the author analyzed the emittance growth caused by the jump of the electric field in an accelerator, energy increase, wakefield in a waveguide, space charge effect and distribution of particles in a beam as well as the wakefield in a deflect system etc. The author also estimated the emittance change caused by the variation of the microwave field from the gun to the first accelerator for such case.
The formation of a quasiequilibrium beam distribution matched to an alternating-gradient quadrupole focusing lattice by means of the adiabatic turn-on of the oscillating focusing field is studied numerically using particle-in-cell simulations. Quiescent beam propagation over several hundred lattice periods is demonstrated for a broad range of beam intensities and vacuum phase advances describing the strength of the oscillating focusing field. Properties of the matched-beam distribution are investigated. In particular, self-similar evolution of the beam density profile is observed over a wide range of system parameters. The numerical simulations are performed using the WARP particle-in-cell code.
Electrostatic plasma simulation code for 2D rectangular geometry is presented. Main distinguishing feature of the code is its orientation on the beam-plasma interaction. The code and its graphical interface were developed using MATLAB programming language. Simulation results of inhomogeneous plasma interaction with modulated electron beams of different width are compared. In case of wide beam the front of Langmuir waves generated in point of local plasma resonance is planar and in case of thin beam (or ribbon beam) the front has approximately half-circular form.
The purpose of this study was to evaluate the resin-dentin interfacial morphology and shear bond strength of several new and experimental dentin bonding systems classified as single-bottle/total etch, multi-step/total etch, and self-etching. Class 1 and 5 cavities were prepared from freshly extracted permanent molars and restored with composite resin. Each bonded sample was cross sectioned and one-half was completely demineralized and deproteinized, while the other half was polished along the cut surface to permit measurement of the thickness of resin-infiltrated dentin layer (RIDL) within intertubular dentin (iRIDL) and around the peritubular walls (pRIDL) of resin tags by SEM. Shear bond strength was measured for all the systems 2 minutes after photocuring. SEM showed iRIDL and resin tags of different morphology depending on material and dentin location. The iRIDL was thinner in superficial dentin and thicker in deep dentin. Peritubular RIDL ...
Remotely-fielded unattended sensor networks generally must operate at very low power--in the milliwatt or microwatt range--and thus have extremely limited communications bandwidth. Such sensors might be asleep most of the time to conserve power, waking only occasionally to transmit a few bits. RFID tags for tracking or material control have similarly tight bandwidth constraints, and emerging nanotechnology devices will be even more limited. Since transmitted data is subject to spoofing, and since sensors might be located in uncontrolled environments vulnerable to physical tampering, the high-consequence data generated by such systems must be protected by cryptographically sound authentication mechanisms; but such mechanisms are often lacking in current sensor networks. One reason for this undesirable situation is that standard authentication methods become impractical or impossible when bandwidth is severely constrained; if messages are small, a standard digital ...
A scheme of evaluating a generalized three-photon excitation cross section sigma/sub (3)/ in neutral atomic argon at 3144.67 A is outlined. Three photons at this wavelength can excite the neutral argon atoms from the ground 3p/sup 6/ /sup 1/S/sub 0/ state to the 3p/sup 5/4s'(1/2)/sub 1//sup 0/ state. The fourth photon will ionize the argon atoms. Assuming linear polarization of the incident laser radiation, contributions from several channels in various energy-level schemes are summed in the evaluation of the transition probability. For a laser linewidth of ..delta..lambda/sub L/ = 1 A, our maximum numerical value of the computed result for the three-photon excitation cross section is sigma/sub (3)/ = 1.414 x 10/sup -80/ cm/sup 6/ s/sup 2/. .AE
... Each beam finite element was derived using Hamilton's principle and the following basic assumptions: the beam has an arbitrary amount of pretwist ...
This report reviews Soviet R and D of (1) high-intensity negative ion sources and (2) transport and focusing of negative ion beams, using Soviet open literature of the past ten years, and correlates this data with data on Soviet institutes responsible for negative ion beam development. The Soviets are developing intense negative ion beams as the basis for creating neutral beams for injection into mirror traps and tokamaks, for inertial confinement fusion, and possibly for exoatmospheric beam weapon applications. The report focuses specifically on surface-plasma-type ion sources, which were first developed in the USSR and which show great promise for creating beams of high intensity, high brightness, and low emittance. Mechanisms for optimum negative ion beam transport are also discussed.
A study of the electron beam dynamics in the linac is conducted for the FERMI free electron laser (FEL) founded for construction at the Sincrotrone Trieste.
A study of the electron beam dynamics in the linac is conducted for the FERMI free electron laser (FEL) founded for construction at the Sincrotrone Trieste
... electronic feedback system' connected to a Q switch ... The use of acousto-optic (AO) beam steering devices for BMDO (SDI) applications is very ...
Consideration is given to the stability of negative ion beams which are neutralized through ionization of a background gas. Two types of instabilities are examined. First, beam-plasma instabilities are analyzed with the dispersion relation showing that they are unimportant if the beam velocity is less than the electron thermal velocity. Second, results of a computer simulation on the flow of a cylindrical beam and the resulting background plasma show that when the background neutral gas density is less than or approximately equal to a critical density as instability occurs. This critical density is the density that would be needed to space-charge neutralize the beam if the positive ions were not retarded by the beam. An approximate dispersion relation indicates that the nature of the instability is a transverse positive-ion acoustic wave which couples to the ...
The performance of bunch-feedback systems based on two-tap FIR filters is discussed, particularly for transverse cases. Since they are the simplest type of FIR digital filters, the two-tap FIR filters should be suited to systems that require a very fast processing speed. However, in these feedback systems, a bunch must turn along a ring several times from the position-measurement to feedback kicking. Within these turns, irregular phase-jumps in the betatron motion can occur, due to several causes, such as the wake forces and beam-beam force. The discussion given in this paper is focussed on the effect of beam-beam collisions on these feedback systems. Based on linear theory and simulation studies, it has been found that these feedback systems can work with good performance, even under the influence of a strong beam-beam force. (author)
Aug. 24, 1965. L. V. BALDWIN ETAL. 3202915. PARTICLE BEAM MEASUREMENT APPARATUS USING BEAM KINETIC. ENERGY TO CHANGE TIIE HEAT SENSITIVE RESISTANCE OF ...
There is currently great interest in combining focused ion beam (FIB) and scanning electron microscopy technologies for advanced studies of polymeric materials and biological microstructures, as well as for sophisticated nanoscale fabrication and prototyping. Irradiation of electrically insulating materials with a positive ion beam in high vacuum can lead to the accumulation of charge, causing deflection of the ion beam. The resultant image drift has significant consequences upon the accuracy and quality of FIB milling, imaging and chemical vapour deposition. A method is described for suppressing ion beam drift using a defocused, low-energy primary electron beam, leading to the derivation of a mathematical expression to correlate the ion and electron beam energies and currents with other parameters required for electrically stabilizing these challenging ...
A 20-MeV proton accelerator is developed by Proton Engineering Frontier Project (PEFP) at Korea Atomic Energy Research Institute (KAERI). The 20MeV accelerator consists of 50keV proton injector, 3MeV RFQ (Radio frequency Quadrupole), 20MeV DTL (Drift Tube Linac) and 20MeV beam line. The beam profile was measured at the end of the 20MeV beam line with wire scanner. Moreover the beam emittance was calculated from the quad scan method using beam line quadrupole magnets. In this paper, the beam profile measurement results are presented and the emittance measurement from the quad scan method is discussed
Accelerator concepts for heavy-ion fusion require small emittance, high-current beams. Such applications could include funnels in which high-current, like-charged particle beams are interlaced to double beam current while retaining small emittances. The first experimental demonstration confirming the beam dynamics of the funnel principle was recently completed at Los Alamos National Laboratory. A single-leg prototype 5-MeV, H{sup {minus}} funnel was successfully tested. This single-beam demonstration explored physics issues of a two-beam funnel. It contained elements for emittance control, position control, and rf deflection, as well as diagnostics for measurement of beam intensity, position and angle centroids, energy and phase centroids, and transverse and longitudinal phase-space distributions. Results of the experiment will be presented ...
Background and purpose: To compare 6 MV and 18 MV photon intensity modulated radiotherapy (IMRT) for non-small cell lung cancer. Materials and methods: Doses for a cohort of 10 patients, typical for our department, were computed with a commercially available convolution/superposition (CS) algorithm. Final dose computation was also performed with a dedicated IMRT Monte Carlo dose engine (MCDE). Results: CS plans showed higher D _9_5_% (Gy) for the GTV (68.13 vs 67.36, p = 0.004) and CTV (67.23 vs 66.87, p = 0.028) with 18 than with 6 MV photons. MCDE computations demonstrated higher doses with 6 MV than 18 MV in D _9_5_% for the PTV (64.62 vs 63.64, p = 0.009), PTV_o_p_t_i_m (65.48 vs 64.83, p = 0.014) and CTV (66.22 vs 65.64, p = 0.027). Dose inhomogeneity was lower with 18 than with 6 MV photons for GTV (0.08 vs 0.09, p = 0.007) and CTV (0.10 vs 0.11, p = 0.045) in CS but not MCDE plans. 6 MV photons ...
The NuMI beam at Fermilab has delivered over 5 x 10{sup 20} 120 GeV protons to the neutrino production target since the start for MINOS [1] neutrino oscillation experiment operation in 2005. We report on proton beam commissioning and operation status, including successes and challenges with this beam.
Monochromator stabilization (MOSTAB) is a feedback control system to stabilize an x-ray beam of synchrotron radiation. It applies a feedback voltage to a piezo electric transducer attached to a double-crystal monochromator. We developed MOSTAB modules and examined their performances using SPring-8 beamlines. The x-ray beam position stabilization using MOSTAB was realized simultaneously with the x-ray beam intensity stabilization. As an example of its application, we performed EXAFS measurement with MOSTAB. (author)
Various methods have been proposed to condition an electron beam in order to reduce its emittance effect and to improve the short-wavelength free electron laser (FEL) performance. In this paper, we show that beam conditioning does not result in a complete elimination of the emittance effect in an alternating-gradient focusing FEL undulator. Using a one-dimensional model and a three-dimensional simulation code, we derive a criteria for the emittance limitation of a perfectly conditioned beam that depends on the focusing structure.
Electromagnetic effects excited by intense relativistic electron beams in plasmas are investigated using a two-dimensional particle code. The simulations with dense beams show large magnetic fields excited by the Weibel instability as well as sizeable electromagnetic radiation over a significant range of frequencies. The possible relevance of beam plasma instabilities to the laser acceleration of particles is briefly discussed. 6 refs., 4 figs.
Accelerators can not be improved without the development of adequate beam instruments and diagnostic tools. This year this statement is particularly right: a lot of contributions are dedicated to beam monitoring and to the design of new beam monitors based on original technologies. This document gathers about 100 contributions.
We describe calculations of the energy loss, range, stopping power, multiple scattering, and other related properties of a high-energy heavy-ion beam at any one of a set of beam line elements. A beam line element (e.g., any beam modification, detection, or control device) is characterized by its thickness, areal density, aperture, and function. The loss of multiply scattered particles to any finite-aperture detector is calculated in the small-angle approximation, and the position of the Bragg peak, as given by particles stopping in the second of two ionization chambers used for Bragg curve measurements, is estimated. A general purpose computer program, PROPAGATE, has been written to allow addition, deletion, and modification of the beam line elements used in the calculation and to provide a convenient means of repeating such calculations for arbitrary beam ...
The properties of negative-ion beams are very important for designing negative-ion apparatus and applications of negative-ion beams, especially, electron detachment cross-sections at the interaction between negative-ion beams and gas particles in the transport system, and secondary-electron emission factors when negative ions are incident on solid surfaces. These properties of negative-ion beams were investigated experimentally as a function of the ion energy under 50 keV. The single electron detachment cross-sections are almost constant in the other of 10[sup -15] cm[sup 2] in this energy range, but double electron detachment cross-sections increase in proportion to the ion velocity and much smaller than the single one. As for the secondary-electron emission factor, the emission factors for negative-ion beam are found to be larger by 1 than those for positive-ion ...
The properties of negative-ion beams are very important for designing negative-ion apparatus and applications of negative-ion beams, especially, electron detachment cross-sections at the interaction between negative-ion beams and gas particles in the transport system, and secondary-electron emission factors when negative ions are incident on solid surfaces. These properties of negative-ion beams were investigated experimentally as a function of the ion energy under 50 keV. The single electron detachment cross-sections are almost constant in the other of 10"-"1"5 cm"2 in this energy range, but double electron detachment cross-sections increase in proportion to the ion velocity and much smaller than the single one. As for the secondary-electron emission factor, the emission factors for negative-ion beam are found to be larger by 1 than those for positive-ion ...
Total M shell X-ray production cross section for 11 elements with 69 #<=# Z #<=# 92 have been measured using an incident photon energy of 5.96 keV. Measurements have been performed using an "5"5Fe annular source and a Si(Li) detector. Average M shell fluorescence yield at each incident photon energy has been deduced, using the experimental total M X-ray production cross section and theoretical M shell photoionization cross section. Present experimental results are compared with other experimental and theoretical values. Reasonable agreement (to within 0.3-28%) is typically obtained between present and other experimental and theoretical values.
We investigate the semihard production of neutral pseudoscalar and tensor mesons in high-energy [gamma][gamma] collisions (M=P=[pi][sup 0], [eta], [eta]' or M=T=a[sub 2], f[sub 2], f[sub 2]'). We deal with the exclusive [gamma][gamma][yields]MM' or semi-exclusive [gamma][gamma][yields]MX reactions (X is the hadron jet with not too large mass). The considered transfer momenta are small in comparison with the photon energies and they are large in comparison with the confinement scale. The amplitudes of these processes are determined by the odderon exchange, i.e. three-gluon exchange in the lowest order of perturbative QCD. The cross sections are calculated in this approximation. The possibility of measurements at LEP and at future [gamma][gamma] colliders is discussed. (orig.).
Atomic ensembles, comprising clouds of atoms addressed by laser fields, provide an attractive system for both the storage of quantum information and the coherent conversion of quantum information between atomic and optical degrees of freedom. We describe a scheme for full-scale quantum computing with atomic ensembles, in which qubits are encoded in symmetric collective excitations of many atoms. We consider the most important sources of error-imperfect exciton-photon coupling and photon losses-and demonstrate that the scheme is extremely robust against these processes: the required photon emission and collection efficiency threshold is #approx#>86%. Our scheme uses similar methods to those already demonstrated experimentally in the context of quantum repeater schemes and yet has information processing capabilities far beyond those proposals.
A quantum mechanical analysis of the guided light in integrated photonics waveguides is presented. The analysis is made starting from one-dimensional (1D) guided vector modes by taking into account the modal orthonormalization property on a cross section of an optical waveguide, the vector structure of the guided optical modes and the reversal-time symmetry in order to quantize the 1D vector modes and to derive the quantum momentum operator and the Heisenberg equations. The results provide a quantum-consistent formulation of the linear and nonlinear quantum light propagations as a function of forward and backward creation and annihilation operators in integrated photonics. As an illustration, an application to an integrated nonlinear directional coupler is given, that is, both the nonlinear momentum and the Heisenberg equations of the nonlinear coupler are derived.
We compute QCD corrections to the production of a ttbar pair in association with a hard photon at the Tevatron and the LHC. This process allows a direct measurement of the top quark electromagnetic couplings that, at the moment, are only loosely constrained. We include top quark decays, treating them in the narrow width approximation, and retain spin correlations of final-state particles. Photon radiation off top quark decay products is included in our calculation and yields a significant contribution to the cross-section. We study next-to-leading order QCD corrections to the ppbar -> ttbar+gamma process at the Tevatron for the selection criteria used in a recent measurement by the CDF collaboration. We also discuss the impact of QCD corrections to the pp -> ttbar+gamma process on the measurement of the top quark electric charge at the 14 TeV LHC.
Generally the photonic band gap (PBG) is a multi-variable function of several parameters related to the shape and size of the dielectric columns of photonic crystals (PhCs), and a time-consuming step-by-step scanning process for each parameter has to be used to find their best combination yielding maximum PBG. In this letter, the widely used Nelder-Mead simplex algorithm is introduced to optimize these parameters simultaneously to find a larger PBG for a new kind of two-dimensional (2D) hexagonal GaAs-Air PhC. This structure can be conveniently produced by the single-exposure holographic lithography, and the specific holographic design is also systematically investigated. This study reveals that the band gaps of PhCs made by holographic lithography may be widened by introducing irregularity of the columns and lowering the symmetry of the structure.
An ytterbium-169 high dose rate brachytherapy source, distinguished by an intensity-weighted average photon energy of 92.7 keV and a 32.015#+-#0.009 day half-life, is characterized in terms of the updated AAPM Task Group Report No. 43 specifications using the MCNP5 Monte Carlo computer code. In accordance with these specifications, the investigation included Monte Carlo simulations both in water and air with the in-air photon spectrum filtered to remove low-energy photons below 10 keV. TG-43 dosimetric data including S_K, D(r,#theta#), #LAMBDA#, g_L(r), F(r,#theta#), #phi#_a_n(r), and #phi#_a_n were calculated and statistical uncertainties in these parameters were derived and calculated in the appendix.
The photon-proton total cross section has been measured in the process e{sup +}p{yields}e{sup +}{gamma}p{yields}e{sup +}X with the ZEUS detector at HERA. Events were collected with photon virtuality Q{sup 2}<0.02 GeV{sup 2} and average {gamma}p center-of-mass energy W{sub {gamma}}{sub p}=209 GeV in a dedicated run, designed to control systematic effects, with an integrated luminosity of 49 nb{sup -1}. The measured total cross section is {sigma}{sub tot}{sup {gamma}}{sup p}=174{+-}1 (stat.){+-}13 (syst.) {mu}b. The energy dependence of the cross section is compatible with parameterizations of high-energy pp and pp-bar data.
We investigate the possibility of implementing a given projection measurement using linear optics and arbitrarily fast feedforward based on the continuous detection of photons. In particular, we systematically derive the so-called Dolinar scheme that achieves the minimum-error discrimination of binary coherent states. Moreover, we show that the Dolinar-type approach can also be applied to projection measurements in the regime of photonic-qubit signals. Our results demonstrate that for implementing a projection measurement with linear optics, in principle, unit success probability may be approached even without the use of expensive entangled auxiliary states, as they are needed in all known (near-)deterministic linear-optics proposals.
Summary Metabotropic GABAB receptors play a fundamental role in modulating the excitability of neurons and circuits throughout the brain. These receptors influence synaptic transmission by inhibiting presynaptic release or activating postsynaptic potassium channels. However, their ability to directly influence different types of postsynaptic glutamate receptors remains unresolved. Here we examine GABAB receptor modulation in layer 2/3 pyramidal neurons from the mouse prefrontal cortex. We use two-photon laser-scanning microscopy to study synaptic modulation at individual dendritic spines. Using two-photon optical quantal analysis, we first demonstrate robust presynaptic modulation of multivesicular release at single synapses. Using two-photon glutamate uncaging, we then reveal that GABAB r...
The effects of intradot electron-electron interaction on the photon-assisted Andreev tunneling of a superconductor/carbon-nanotube/superconductor system are studied by using nonequilibrium Green's function technique. The inverse supercurrent reflecting the #pi#-junction transition emerges in the spin-split energy-levels regime polarized by the Coulomb interaction. For the positive tunneling case, the supercurrent reaches its maximum when the spin-degenerate energy-levels are nearest to the Fermi surface. Conversely, for the negative tunneling case, the supercurrent reaches its maximum when two split energy-levels are symmetric with respect of the Fermi surface. The sign and the amplitude of the Andreev tunneling depend distinctly on the energy-level spacing tuned by photon-assisted tunneling. In order to fully understand the transport characteristics, the current-carrying density of states are investigated, which clearly shows the enhancement, ...
While it is quite obvious that photons have an essential role in photochemical and photocatalytic processes, it is not simple to analyse the radiation process. A simple approach is presented on the assumption that photons can be treated as immaterial reactants. It is then possible to evaluate the radiation process in terms of parameters such as conversion, selectivity and yield, which are common in the conventional reaction engineering, and of an additional parameter, a volume efficiency factor, which accounts for the exploitation of the reaction volume as the result of the inevitable attenuation of the radiation in the transport through the participating medium. Attention has also been focused on the validation of kinetic data when, as it is usually done, they are interpreted in terms of volume averages. Finally, guidelines have been prepared to support preliminary phases of analysis and/or design of a photocatalytic reactor. (author)
The proton and deuteron spectra following resonant multiphoton ionization of H{sub 2} and HD at 193 nm through the {ital E},{ital F} state have been studied at power densities of 10{sup 10} W/cm{sup 2}. Our results show that the intermediate state induces competition between 3(2+1)-photon ionization, dissociation, and dissociative ionization channels. We find that the competition depends on the specific vibrational and rotational levels excited in the intermediate state. At the same time, the mere presence of this bound intermediate state renders these three-photon fragmentation channels so efficient that higher-order fragmentation processes, such as Coulomb explosions requiring many more photons, are not observed.
An estimate for the number of ionizing photons per baryon as a function of redshift is computed based on the plausible extrapolation of the observed galaxy UV luminosity function and the latest results on the properties of the escape fraction of ionizing radiation. It is found that, if the escape fraction for low mass galaxies (Mtot<10^{11}Msun) is assumed to be negligibly small, as indicated by numerical simulations, then there are not enough ionizing photons to reionize the universe by z=6 for the cosmology favored by the WMAP 3rd year results, while the WMAP 1st year cosmology is marginally consistent with the reionization requirement. The escape fraction as a function of galaxy mass would have to be constant to within a factor of two for the whole mass range of galaxies for reionization to be possible within the WMAP 3rd year cosmology.
Taking the development of large current, negative ion sources which is in progress aiming at nuclear fusion reactors and the development of high luminance ion sources planned as a part of the Omega Project as the examples, the technology for generating high power ion beams is explained. Both these projects are positioned at the limit of the present technology of high power ion beam application as their targeted beam power reaches several tens MW. Consequently, the requirement for the ion sources is severe, and in particular, the generation of the ion beams having large current density with good convergence is beyond all precedents. The application of high power ion sources has been realized as the neutral beam injectors for large tokamaks. Also the hydrogen negative ion source of large current and the electrostatic acceleration technology for negative ion beams ...
A book has been written to introduce the physical aspects of the radiotherapy electron beam by presenting a summary of the developments in this field. The first chapter is a brief introduction to the technology of medical accelerators with emphasis on the electron beam production facilities. Chapter 2 describes the interaction processes at the atomic level once the electron beam enters the medium. Chapter 3 is concerned with the various properties of the electron beam purely from the clinical point of view. The electron beam algorithms and models for distribution calculations are covered in Chapter 4 with inclusion of age diffusion and multiple scattering approaches. The factors affecting the beam distribution in a patient, with inhomogeneities, surface irregularities, backscattering etc. are discussed in Chapter 5. The last two chapters are devoted to electron ...
In the case of total skin electron therapy without the beam guide, the electron beam is scattered just outside the gantry exit, dose uniformity in the field is broken, and dose is spread outside the light field. The aims of this study were to measure the mean energy of the off-axis incident electron beam without the beam guide and to establish a reference for the clinical situation. For the measurement, a 4 MeV electron beam was selected among several energies from the linear accelerator. A scintillating fiber beam energy monitor measured the mean energy of the incident electron beam. This energy monitor is a small, light-weight piece of equipment composed of a wedge absorber, scintillation fiber, and photodiode. We found the relationship between electron energy and the indicated value of the energy monitor by means of the estimation of ...
The polarization of extracted SATURNE II proton beam as a function of different ion source configurations was studied. Two distinct experiments were necessary for this purpose. In the first one, the left-right instrumental asymmetry of the beam polarimeter was determined using an unpolarized beam. In the second one this correction factor was applied to asymmetries measured with the beam from the polarized ion source in all polarization states. The measurements were carried out at the proton beam kinetic energy 0.80 GeV, where the pp-elastic scattering analyzing power is near its maximum. The results confirmed that the two so-called ``unpolarized states`` of the source were polarized to several percent, whereas the absolute values of the beam polarizations in the so-called ``polarized states`` were equal and opposite. It was observed that the hexapole lens of the ...
This paper deals with the buffeting of a slender, circular, flexible beam-rod in an axial turbulent flow. The principal excitation mechanisms are the turbulent wall pressure fluctuations and the motion-dependent (self-excited) aerodynamic force caused by the beam motion. On the assumption that the turbulent wall pressure fluctuations are independent of the beam motion, a linear forced-vibration model is used to determine the buffeting response of the beam and to investigate the length scale effects of turbulences on the beam buffeting. Transverse buffeting of the beam in an axial turbulent flow depends largely on the ratio of the longitudinal scale of the turbulences to the bending wavelength of the beam and on the ratio of the circumferential scale of the turbulences to the radius of the beam. The spectra and the mean ...
In various situations, measurements in prompt gamma neutron activation analysis (PGNAA) are performed to determine the amount of an elemental impurity relative to that of a major constituent of the matrix. An example of this is the measurement of hydrogen concentration in a metallic matrix. In all such cases, a major contributor to the uncertainty in the measurement is the uncertainty in the ratio of the high-purity germanium (HPGe) detector full-energy peak efficiency for the gamma-ray lines of interest (i.e., impurity and matrix gammas). Usually, the ratio is derived from the relative peak efficiency curve, which is determined using isotopic standards that emit multiple gamma ray lines (e.g., "1"5"2Eu) in the energy range <3000 keV, or using prompt gamma radionuclides (e.g., "1"4N, "3"5Cl) in the energy range >3000 keV. In either case, the uncertainty in the ratio of the peak efficiency values derived from such measurements will be on the order of a few percent at best because ...
The conceptual design for a cyclotron that could possibly deliver a 10 MW proton beam, presented at the previous ADTT conference, is discussed in comparison with the operational experience gained with 0.9 MW beam power in the upgraded cyclotron facility at PSI that has reached the design goal of 1.5 mA at 590 MeV in 1995. Some critical aspects of the design are e.g. RF power and beam loading, beam loss and activation, space charge effects and bunching. 12 refs., 2 figs., 1 tab.
The most propagated mechanisms of stimulated radiation of electron beam such as Cherenkov one-particle and collective effects, ondulator and magnetic bremsshrahlung radiations, Doppler anomalous effect, Thompson and Raman scattering and radiation are discussed. Relation of spontaneous radiation mechanisms of individual electron and stimulated radiation effects in electron beams has been elucidated, grounds of linear electrodynamics of radiative beam instabilities are stated, and main mechanisms of their nonlinear stabilization are elucidated as well. Various simulated processes in electron beams are considered from the unique point of view using a simple mathematical apparatus and such physical laws as conservation and Newton laws.
Requirements are provided for NSLS beam line front ends and vacuum interlocks. Guidelines are provided for UHV beam line vacuum systems, including materials, vacuum hardware (pumps, valves, and flanges), acoustic delay lines and beam line fast valves, instrumentation, fabrication and testing, and the NSLS cleaning facility. Also discussed are the design review for experimenters' equipment that would be connected to the NSLS and acceptance tests for any beam line to be connected with the ring vacuum. Also appended are a description of the acoustic delay line as well as the NSLS vacuum standards and NSLS procedures. (LEW)
We discuss polarizing a proton beam in a storage ring, either by selective removal or by spin flip of the stored ions. Prompted by recent, conflicting calculations, we have carried out a measurement of the spin-flip cross section in low-energy electron-proton scattering. The experiment uses the cooling electron beam at COSY as an electron target. The measured cross sections are too small for making spin flip a viable tool in polarizing a stored beam. This invalidates a recent proposal to use co-moving polarized positrons to polarize a stored antiproton beam.
Plasma generated in low-density vapor by a negative ion beam has been studied experimentally and computationally. We show that space charge neutralization of the beam occurs at very low vapor density, and that correspondingly the electron density may be much less than the beam and plasma ion densities. When there is a large local gas density, as in a charge changing cell, the resulting high electron density is also localized to the same region. Therefore, very few electrons will reach a negative ion accelerator even if it is placed one or two beam diameters from such a cell.
In drift tube linacs a beam energy spread results form the finite beam size. Radial variation of the axial accelerating field induces a beam energy spread, which, in general, will accumulate as the beam passes through successive drift tubes. This paper shows that under some conditions of periodic transverse focusing and longitudinal phase focusing, the correlation between the longitudinal and transverse motion can be used to correct the energy spread. The process of achieving such a correction is first described in a simplified situation, and then demonstrated for a particular tuning using a ray-tracing program which models a low velocity and low charge state linac designed for radioactive ion beams.
With the development of an array of highly-segmented germanium detectors, it now becomes possible to perform in-flight #gamma#-ray spectroscopy experiments on intermediate energy beams with unprecedented #gamma#-ray energy resolution. Presented in this report are examples of two techniques in which SeGA, the most highly-segmented operational germanium array for in-flight spectroscopy with fast beams, was used for the detection of #gamma# rays. SeGA used in conjunction with a high-resolution magnetic spectrograph (S800) to detect the reaction residues in coincidence represents a powerful combination for in-beam #gamma#-ray studies.
The inelastic scattering of the beam and the residual gas molecules in RHIC could represent one of the limitations on the beam life time and emittance growth. This report covers the dominant central nuclear collisions influence on the beam lifetime and transverse emittance growth. The cross sections for the beam-gas electron radiative captures are an order of magnitude smaller. The capture cross sections include the radiative and non-radiative capture, and the capture from the electron-positron pair creation from the 'vacuum capture'.
We apply and modify the computer codes CAIN(P.Chen, G.Horton-Smith, T.Ohgaki, A.W.Weidemann, K.Yokoya, contributed to Workshop on Gamma-Gamma Colliders, Berkeley, CA, March 28-31, 1994; SLAC-PUB-6583.) and GUINEAPIG(D.Schulte (DESY), unpublished.) to make detailed studies of the beam-beam interaction in the SLAC design for a future linear collider (NLC), as well as to the proposed SLC2000 project. Using realistic beam distributions, we present simulations related to the tuning and optimization of luminosity in SLC2000 and NLC.
We apply and modify the computer codes CAIN(P.Chen, G.Horton-Smith, T.Ohgaki, A.W.Weidemann, K.Yokoya, contributed to Workshop on Gamma-Gamma Colliders, Berkeley, CA, March 28-31, 1994; SLAC-PUB-6583.) and GUINEAPIG(D.Schulte (DESY), unpublished.) to make detailed studies of the beam-beam interaction in the SLAC design for a future linear collider (NLC), as well as to the proposed SLC2000 project. Using realistic beam distributions, we present simulations related to the tuning and optimization of luminosity in SLC2000 and NLC.
Longitudinal space charge (LSC) force can be a main effect driving the microbunching instability in the linac for an x-ray free-electron laser (FEL). In this paper, the LSC-induced beam modulation is studied using an integral equation approach that takes into account the transverse (radial) variation of LSC field for both the coasting beam limit and bunched beam. Changes of beam energy and the transverse beam size can be also incorporated. We discuss the validity of this approach and compare it with other analyses as well as numerical simulations.
A thermal-resistant radiation sensing system using optical fiber has been developed. The system is for monitoring progress of chemical decontamination and able to measure the gamma-ray level in a hot solution of decontamination chemicals in situ. Our sensor head makes use of thermal-resistant NaI (T1) and it is connected to an optical fiber bundle. Scintillation photons pass from the NaI (T1) into the end of the bundle. This part of the system can withstand temperatures of over 100degC. At the far end of the optical fiber bundle, the scintillation photons are converted into fluorescent photons using a wavelength-shifting fiber. These photons are transferred to a distant photomultiplier tube through two thin transparent optical fibers. Furthermore, we propose a self-compensation technique for the dependence of scintillator sensitivity on. This compensation method is based on the correlation between ...
tial/angular spreading of incident photons from a point source caused by the instrument (de- .... Filter. CDTP0001= 'DATA. ' / Type of calibration. CCNM0001= '2D_PSF ' ... the final resolution of sigma=0.5 arcmin in all energy bands. ...
Neuroblasts born in the adult subventricular zone (SVZ) migrate long distances in the rostral migratory stream (RMS) to the olfactory bulbs where they integrate into circuitry as functional interneurons....Full Text Available
We point out that electromagnetic one-way edge modes analogous to quantum Hall edge states, originally predicted by Raghu and Haldane in 2D gyroelectric photonic crystals possessing Dirac point-derived bandgaps, can appear in more general settings. In particular, we show that the TM modes in a gyromagnetic photonic crystal can be formally mapped to electronic wavefunctions in a periodic electromagnetic field, so that the only requirement for the existence of one-way edge modes is that the Chern number for all bands below a gap is non-zero. In a square-lattice gyromagnetic Yttrium-Iron-Garnet photonic crystal operating at microwave frequencies, which lacks Dirac points, time-reversal breaking is strong enough that the effect should be easily observable. For realistic material parameters, the edge modes occupy a 10% band gap. Numerical simulations of a one-way waveguide incorporating this crystal show 100% transmission across ...
First comprehensive data on the evolution of nucleon resonance photocouplings with photon virtuality Q{sup 2} are presented for excited proton states in the mass range from 1.4 to 2.0 GeV.
Reliable values of x-ray and gamma-ray attenuation coefficients of elements and compounds are required in spectrometry as well as in many other scientific, engineering and medical disciplines involving photon radiation
The presented results are the first measurements at RHIC for direct $\\gamma$-charged hadron azimuthal correlations in heavy ion collisions. We use these correlations to study the color charge density of the medium through the medium-induced modification of high-p$_T$ parton fragmentation. Azimuthal correlations of direct photons at high transverse energy (8 $<$ p$_T$ $<$ 16 GeV) with away-side charged hadrons of transverse momentum (3 $<$ p$_T$ $<$ 6 GeV/c) have been measured over a broad range of centrality for $Au+Au$ collisions and $p+p$ collisions at $\\sqrt{s_{NN}}$ = 200 GeV in the STAR experiment. A transverse shower shape analysis in the STAR Barrel Electromagnetic Calorimeter Shower Maximum Detector is used to discriminate between the direct photons and photons from the decays of high p$_T$ $\\pi^{0}$. The per-trigger away-side yield of direct $\\gamma$ is smaller than from $\\pi^{0}$ trigger at the ...
Photosynthetic antenna complexes capture and concentrate solar radiation by transferring the excitation to the reaction center that stores energy from the photon in chemical bonds. This process occurs...Full Text Available
To determine the diagnostic accuracy of iofetamine hydrochloride I 123 (IMP) with single photon emission computed tomography in Alzheimer's disease, we studied 58 patients with AD and 15 age-matched healthy control subjects. We used a qualitative method to assess regional IMP uptake in the entire brain and to rate image data sets as normal or abnormal without knowledge of subjects'clinical classification. The sensitivity and specificity of IMP with single photon emission computed tomography in AD were 88% and 87%, respectively. In 15 patients with mild cognitive deficits (Blessed Dementia Scale score, less than or equal to 10), sensitivity was 80%. With the use of a semiquantitative measure of regional cortical IMP uptake, the parietal lobes were the most functionally impaired in AD and the most strongly associated with the patients' Blessed Dementia Scale scores. These results indicated that IMP with single ...
Photon migration provides sensitive tissue oximetry in which the optical pathlength is known. Phase array gives the precise location of a subnanomolar amount of hidden absorber in highly scattering medium. PMID:8079713
A photon-induced x-ray fluorescence method allowing the simultaneous determination of iron, copper, zinc, bromine and rubidium in human blood and blood plasma samples is described. The method is reliable and has a good sensitivity for a wide range of elements. (author).
The lymphographic agent Lipiodol (iodized oil) has been found to localize and remain in tumor vessels. Based on this finding, we attempted transcatheter internal radiotherapy by radioactive iodized oil (I-131 tagged Lipiodol) prepared by isotopic exchange reaction. Transcatheter internal radiotherapy (TCIR) was attempted in twelve patients with inoperable hepatoma by infusing a therapeutic dose of I-131 Lipiodol (7.6 approx. 28.3 mCi/2.0 approx. 5.0 ml) via the hepatic artery. Serial changes of serum alpha-fetoprotein (AFP) levels and in the size of tumor on computed tomography (CT) were estimated to evaluate the therapeutic effect. Serum AFP levels decreased in 9 patients with initial elevated levels of serum AFP, although they were again elevated in three of them within four weeks. More than 50 % decrease in tumor size was observed in 6 patients (50 %). There were no serious complications. This preliminary results suggest that TCIR with I-131 Lipiodol will be one ...
On February 20th 1998 Auckland, the biggest city of New Zealand, was nearly paralyzed by an extended power failure. On this day the last of four cables supplying the central business district failed and caused a five weeks lasting blackout. This failure has caused costs of 128.3 Mio NZ Dollar for the affected utility Mercury Energy Ltd. The official ministerial inquiry was published on July 21st 1998 and reproaches the utility in an unusual clear manner. (orig.) [Deutsch] Am 20. Februar 1998 wurde Auckland, die groesste Stadt Neuseelands, von einer folgenschweren Unterbrechung der Stromversorgung nahezu lahmgelegt. An diesem Tag fiel das letzte von vier 110-kV-Kabeln zur Versorgung des Innenstadtbereiches aus und verursachte damit einen 5 Wochen dauernden Stromausfall. Diese Versorgungsunterbrechung hat bisher Kosten in Hoehe von 128,3 Mio NZ Dollar (rd. 115,5 Mio DM) fuer den oertlichen Stromversorger Mercury Energy Limited verursacht. Der am 21. Juli 1998 ...
Being able to distinguish light-quark jets from gluon jets on an event-by-event basis could significantly enhance the reach for many new physics searches at the Large Hadron Collider. Through an exhaustive search of existing and novel jet substructure observables, we find that a multivariate approach can filter out over 95% of the gluon jets while keeping more than half of the light-quark jets. Moreover, a combination of two simple variables, the charge track multiplicity and the pT-weighted linear radial moment (girth), can achieve similar results. While this pair appears very promising, our study is only Monte Carlo based, and other discriminants may work better with real data in a realistic experimental environment. To that end, we explore many other observables constructed using different jet sizes and parameters, and highlight those that deserve further theoretical and experimental scrutiny. Additional information, including distributions of around 10,000 variables, can be found ...
Advanced proteomic research efforts involving areas such as systems biology or biomarker discovery are enabled by the use of high level informatics tools that allow the effective analysis of large quantities of differing types of data originating from various studies. Performing such analyses on a large scale is not feasible without a computational platform that performs data processing and management tasks. Such a platform must be able to provide high-throughput operation while having sufficient flexibility to accommodate evolving data analysis tools and methodologies. The Proteomics Research Information Storage and Management System (PRISM) provides a platform that serves the needs of the accurate mass and time tag approach developed at PNNL. PRISM incorporates a diverse set of analysis tools and allows a wide range of operations to be incorporated by using a state machine that is accessible to independent, distributed computational nodes. The system has scaled ...
A measurement of the t{bar t} production cross section at {radical}s = 1.96 TeV in the dilepton final states using a lepton+track selection and secondary vertex b-tagging is presented. One of the two leptons from the decay of the t{bar t} pair is allowed to be identified only as an isolated track to improve the selection efficiency. The result is combined with a measurement in the t{bar t} {yields} e{mu} final state. The measurements are based on 370 pb{sup -1} of data collected with the D0 experiment at the Tevatron collider. The preliminary cross section obtained in the combined lepton+track and e{mu} channel is: {sigma}{sub t{bar t}} = 8.6{sub -1.7}{sup +1.9}(stat) {+-} 1.1(syst) {+-} 0.6(lumi) pb.
Expressed sequence tags (ESTs) of the maxillary galea of the silkworm were analyzed to identify proteins involved in food selection systems. From the 1251 redundant genes of the ESTs, we identified 7 odorant-binding protein-like genes (bmObpL), 6 takeout-like genes (bmToL), and 6 chemosensory protein genes (bmCsp). Quantitative RT-PCR analysis indicated that bmObpL1, bmObpL2, bmObpL3, bmObpL5, bmToL1, bmToL3, and bmorCsp15 were predominantly expressed in the larval oral appendages, such as the maxilla, labrum, labium and antenna. Immunocytochemical analysis indicated that the proteins of bmObpL1, bmObpL3, and bmToL1 were localized in the gustatory chemosensilla on the maxillary galea and olfactory sensilla in the antenna. The proteins encoded by bmObpL1 and bmObpL3 were detected in the gus...
Until recently no active treatment for advanced or metastatic gastrointestinal stroma tumors (GIST) was available. The tyrosine kinase inhibitor imatinib has revolutionized the treatment of this disease and the median overall survival now reaches 5 years. The standard dose of imatinib is 400 mg per day. Locally advanced GIST should be treated with systemic therapy prior to surgical resection. Imatinib was recently licensed for adjuvant therapy following complete surgical removal of GIST in patients with a significant risk of recurrence. (orig.) [German] Bis vor einigen Jahren existierte keine wirksame systemische Therapie fuer fortgeschrittene oder metastasierte gastrointestinale Stromatumoren (GIST). Der Tyrosinkinaseinhibitor Imatinib hat die Behandlung dieser Tumoren revolutioniert, die mediane Ueberlebenszeit liegt heute bei etwa 5 Jahren. Die Standarddosierung von Imatinib betraegt initial 400 mg/Tag. Lokal fortgeschrittene Tumoren werden primaer systemisch ...
The ruptured offshore oil well 80 miles from Mexican town of Ciudad del Carmen, which poured 8000 barrels of light oil a day into the Gulf of Mexico, provided marine scientists with the opportunity to monitor the spill and see what happens to petroleum hydrocarbons in sea water. Scientists followed changes in viscosity, surface tension, and buoyancy of individual oil globs as they moved through the water and interacted with the surface slick. Using gas chromatography and mass spectroscopy, chemists are gaining an understanding of the unique characteristics of the oil. Computer-generated models projected the slick's movement in the Gulf in response to wind and wave pressures, but the sophisticated system did not give an accurate daily prediction. Immediate damage to fish, turtles, and sea birds was documented by tagging. Long-term effects will take longer to ascertain since 25 years is generally required to flush oil out of sediments. Fishermen do not agree ...
SNAP25 occurs on chromosome 20p12.2, which has been linked to schizophrenia in some samples, and recently linked to latent classes of psychotic illness in our sample. SNAP25 is crucial to synaptic functioning, may be involved in axonal growth and dendritic sprouting, and its expression may be decreased in schizophrenia. We genotyped 18 haplotype-tagging SNPs in SNAP25 in a sample of 270 Irish high-density families. Single marker and haplotype analyses were performed in FBAT and PDT. We adjusted for multiple testing by computing q values. Association was followed up in an independent sample of 657 cases and 411 controls. We tested for allelic effects on the clinical phenotype by using the method of sequential addition and 5 factor-derived scores of the OPCRIT. Nine of 18 SNPs had P values Irish family sample. Although we failed to replicate this in an independent sample, this gene should be further tested in other samples. PMID:19806613
At future [gamma][gamma] colliders copious production of [ital t] [bar t] pairs is possible. This would allow for a detailed investigation of the interactions involving the top quark. We propose some correlations which are sensitive to [ital t] [bar t] final state interactions and we compute the QCD and standard model Higgs boson contributions to these correlations. A correlation resulting from the QCD induced transverse polarization of top quarks is found to be sizable and measurable at a high energy [ital e][sup +][ital e][sup [minus
We review some interesting virtual effects from the minimal supersymmetric model (MSSM) at {gamma}{gamma} colliders. We conclude that in the research respects, such as supersymmetric particle pair production, CP-violation and electroweak-like one-loop corrections in top quark pair production, the FCNC in the R{sub p}-violating MSSM, linear collider (LC) operating in photon-photon collision mode provides powerful facilities in the measurements of new physics objects. For a precise and thorough study of the new physics, the investigation of the supersymmetric quantum effects is necessary. (author)
We review some interesting virtual effects from the minimal supersymmetric model (MSSM) at #gamma##gamma# colliders. We conclude that in the research respects, such as supersymmetric particle pair production, CP-violation and electroweak-like one-loop corrections in top quark pair production, the FCNC in the R_p-violating MSSM, linear collider (LC) operating in photon-photon collision mode provides powerful facilities in the measurements of new physics objects. For a precise and thorough study of the new physics, the investigation of the supersymmetric quantum effects is necessary. (author)
The results of photoemission spectroscopy using molybdenum and tantalum samples have been obtained from the new beamline 2B1 at Pohang Light Source. Beamline 2B1 is based on a spherical grating monochromator (SGM) which is equipped with five gratings. The photon energy range from 184 to 1100 eV was covered in this work using two gratings (Gratings 4 and 5). The photon energy resolution has been deduced from Ta Fermi-level spectra and 3d spectra of Mo.
The heavy neutral Higgs bosons H, A in the minimal supersymmetric extension of the standard model can be produced as single resonances at high-energy {gamma}{gamma} colliders. We have studied the prospects of the search for these particles in bb and neutralino-pair final states. The Higgs bosons can be found with masses up to 70-80% of the initial e{sup {+-}}e{sup -} collider energy for medium values of tg{beta}, i.e. in areas of the supersymmetric parameter space not accessible at other colliders. (orig.)
The K-shell X-ray intensity ratios for W, Au, Tl, Pb, Bi, Th and U were measured at a photon incident energy of 121.9 keV from "5"7Co radionuclide. A comparison between the experimental results and the theoretically calculated values shows that the experimental results are, in general, higher than the theoretical values. The measured intensities are regarded to be reported for the first time. (author) 9 refs.; 1 tab.
Measurements of the photon angular distribution of Radiative Electron Capture into the M shell have been performed with He-like uranium ions in the range 110-140 MeV/u. In addition, L REC was studied at a projectile energy of 140 MeV/u. In both cases, the experimental data show an asymmetry around 90 and agree well with a fully relativistic theory. (orig.) 15 refs.
The thermal evolution predicted by current models of the superfluid-crust interaction is noted to differ substantially from the thermal evolution predicted by models without internal heating as well as previous models of heating. Heating rates approaching the maximum predicted by current models enhance the photon luminosity of the star in the neutrino cooling era, and dramatically alter the thermal evolution in the photon cooling era. Standard cooling models are consistent with current pulsar temperature estimates and upper limits, except those for the Vela pulsar, which are lower than predicted. 77 refs.
A finite three-dimensional layer-by-layer photonic crystal with planar defects in a layer is shown to drastically modify the spontaneous emission rate of an embedded dipole. Finite-difference time-domain calculations with one quarter symmetric boundary condition and perfectly matched layer demonstrate the strong enhancement effects induced by the cavity resonance of defect modes and band-edge resonant modes. Simulation shows that the emission spectra are quite different when the position or polarization of the dipole is changed. Moreover, the extraction efficiency is calculated to observe the percentage of light leakage through a substrate.
Total photon attenuation coefficients near absorption edges are determined in certain suitable elements and compounds. Photoelectric cross sections for elements are deduced from these by subtracting the coherent and incoherent scattering cross sections as well as other elemental cross sections in the cases of compounds. Certain deviations are observed on comparison with the available theoretical and experimental compilations. The I/sub L//sub ..cap alpha..//Il x-ray intensity ratio measured by photon excitation near threshold is found to agree better with the theory than the other available experimental data.
Total photon attenuation coefficients near absorption edges are determined in certain suitable elements and compounds. Photoelectric cross sections for elements are deduced from these by subtracting the coherent and incoherent scattering cross sections as well as other elemental cross sections in the cases of compounds. Certain deviations are observed on comparison with the available theoretical and experimental compilations. The I/sub L//sub #alpha#//Il x-ray intensity ratio measured by photon excitation near threshold is found to agree better with the theory than the other available experimental data.
Transformation optics is used to design a gateway that can block electromagnetic waves but allows the passage of other entities. Our conceptual device has the advantage that it can be realized with simple materials and structural parameters and can have a reasonably wide bandwidth. In particular, we show that our system can be implemented by using a magnetic photonic crystal structure that employs a square ray of ferrite rods, and as the field response of ferrites can be tuned by external magnetic fields, we end up with an electromagnetic gateway that can be open or shut using external fields. The functionality is also robust against the positional disorder of the rods that made up the photonic crystal.
We have implemented a virtual Young's double slit experiment for hard X-ray photons with micro-fabricated bi-prisms. We observe fringe patterns with a scintillator, and quantify interferograms by detecting X-ray fluorescence from a scanned 30nm Cr metal film. The observed intensities are best modeled with a near-field, Fresnel analysis. The maximum fringe number in the overlap region is proportional to the ratio of real to imaginary parts refractive index of the prism material. The horizontal and vertical transverse coherence lengths at beamline APS 8-ID are measured.
Transmission electron microscope (TEM) specimens are today routinely prepared using focussed ion beam (FIB) instruments. Specifically, the lift-out method has become an increasingly popular technique and involves removing thin cross-sections from site-specific locations and transferring them to a TEM grid. This lift-out process can either be performed ex situ or in situ. The latter is mainly carried out on combined dual-beam FIB and scanning electron microscope (SEM) systems whereas conventional single-beam instruments often are limited to the traditional ex situ method. It is nevertheless desirable to enhance the capabilities of existing single-beam instruments to allow for in situ lift-out preparation to be performed since this technique offers a number of advantages over the older ex situ method. A single-beam FIB instrument was therefore modified to incorporate an in situ ...
Using a 47 GeV electron beam, the Final Focus Test Beam (FFTB) produces vertical spot sizes around 70 nm. These small beam sizes introduce an excellent opportunity to develop and test high resolution Radio Frequency Beam Position Monitors (RF-BPMs). These BPMs are designed to measure pulse to pulse beam motion (jitter) at a theoretical resolution of approximately 1 nm. The beam induces a TM{sub 110} mode with an amplitude linearly proportional to its charge and displacement from the BPM's (cylindrical cavity) axis. The C-band (5,712 MHz) TM{sub 110} signal is processed and converted into beam position for use by the Stanford Linear Collider (SLC) control system. Presented are the experimental procedures, acquisition, and analysis of data demonstrating resolution of jitter near 25 nm. With the design of future e{sup +}e{sup -} linear ...
In this paper the authors present a design study on the longitudinal dynamics of a relativistic klystron two-beam accelerator (RK-TBA) scheme which has been proposed as a power source candidate for a 1 TeV next linear collider (NLC). They address the issue of maintaining stable power output at desired level for a 300-m long TBA with 150 extraction cavities and present their simulation results to demonstrate that it can be achieved by inductively detuning the extraction cavities to counter the space charge debunching effect on the drive beam. They then carry out simulation study to show that the beam bunches desired by the RK-TBA can be efficiently obtained by first chopping an initially uniform beam of low energy into a train of beam bunches with modest longitudinal dimension and then using the open-quotes adiabatic captureclose quotes scheme to bunch and accelerate these ...
The SPring-8 linac has been improved to realize stable top-up injection into the SPring-8 and the NewSUBARU storage rings. The beam energy instability of 0.02% rms in the long term was achieved by means of reducing RF variations, providing beam energy compensation, reinforcement of monitor systems and introduction of beam feedback controls: Variations in the RF power and phase have been reduced by improving the voltage regulation system for the klystron modulator, and by stabilizing the temperature drift of the atmosphere and cooling water in order to reduce the phase variation. A new synchronous oscillator synchronizes a beam trigger pulse and a 2856 MHz reference signal, reducing variation in the beam charge. A beam energy compression system (ECS) was installed to compensate for accidental energy variation and reduce the energy spread. ...
A large negative ion source for JT-60U produces high current ion beam from a wide extraction area of 45 cm x 110 cm. On the other hand, a cross-sectional area of the negative ion based neutral beam (NNB) injection port on JT-60U is narrow, about 50 cm x 60 cm. In order to inject the neutral beam at a high geometric efficiency, i.e. to suppress beam loss in the beamline, it is necessary to steer the beam for both compensation of undesirable beam deflection in extractor and focusing of the beam. For the JT-60U, two methods are provided for the required beam steering. Among them the results of beam steering experiment by aperture displacement and the design study are summarized in the present report. The experiment was carried out with 400 keV negative ion source, which has the three stage accelerator ...
The results of experiments with a short period (9.6 mm) wiggler sheet electron beam (1.0 mm x 2.0 cm) millimeter-wave free electron laser (FEL) amplifier are presented. This FEL amplifier utilized a strong wiggler field for sheet beam confinement in the narrow beam dimension and an offset-pole side-focusing technique for the wide dimension beam confinement. The beam analysis herein includes finite emittance and space-charge effects. High-current beam propagation was achieved as a result of extensive analytical studies and experimental optimization. A design optimization resulted in a low sensitivity to structure errors and beam velocity spread, as well as a low required beam energy. A maximum gain of 24 dB was achieved with a 1-kW injected signal power at 86 GHz, a 450-kV beam voltage, 17-A ...
A method for simplifying finite element models of structures having a beam-like global dynamical behaviour is presented. This method is based on the use of a general uniform beam finite element formulation. It takes into account both transverse shear effects and dynamical coupling between bending and torsion due to the fact that mass centres and shear centres do not always coincide. For that purpose, we develop a condensation method for reducing any shell model into an equivalent beam, as well as a technique for automatically identifying the corresponding set of beam parameters. The method is applied to several illustrate examples that demonstrate its ability to simplify finite element models for many kinds of sophisticated structures having a beam-like predominant behaviour.
Recently Emma and Stupakov identified a fatal flaw in a Free Electron Laser (FEL) beam conditioning scheme. They showed that the conditioning is always accompanied by a projected transverse emittance growth that is so large as to make the beam conditioning completely impractical for short wavelength FELs. Furthermore, they provided a general proof along with evidence of computer simulation and reached a conclusion that any beam conditioner, regardless of the method, would suffer from the same constraints and limitations. In this paper, the author proposes an easy surgical removal of the fatal flaw by making a critical yet simple modification to the very scheme analyzed, thus resurrect the beam conditioning for short wavelength FELs. More generally, the also explain why a general search for removing have failed, why the concept and definition of beam conditioning.
We discuss the minimum requirements for a neutrino beta beam if theta_13 is discovered by an upcoming reactor experiment, such as Double Chooz or Daya Bay. We require that both neutrino mass hierarchy and leptonic CP violation can be measured to competitive precisions with a single-baseline experiment in the entire remaining theta_13 range. We find that for very high isotope production rates, such as they might be possible using a production ring, a (B,Li) beta beam with a gamma as low as 60 could already be sufficient to perform all of these measurements. If only the often used nominal source luminosities can be achieved, for example, a (Ne,He) beta beam from Fermilab to a possibly existing water Cherenkov detector at Homestake with gamma \\sim 190-350 (depending on the Double Chooz best-fit) could outperform practically any other beam technology including wide-band beam and ...
An assessment of the joint shear strength of exterior concrete beam-column joints reinforced internally with Glass Fibre Reinforced Polymer (GFRP) reinforcements under monotonically increasing load on beams keeping constant load on columns is carried out in this study. Totally eighteen numbers of specimens are cast and tested for different parametric conditions like beam longitudinal reinforcement ratio, concrete strength, column reinforcement ratio, joint aspect ratio and influence of the joint stirrups at the joint. Also finite element analysis is performed to simulate the behaviour of the beam-column joints under various parametric conditions. Based on this study, a modified design equation is proposed for assessing the joint shear strength of the GFRP reinforced beam-column specimens b...
The drift-kink instability in field-reversed configurations with a beam component is investigated by means of a three-dimensional particle simulation. The unstable mode with the toroidal mode number n=4 grows with the rate {gamma} {approx} 0.1 - 1.0{omega}{sub ci} for a strong beam current and deforms the plasma profile along the beam orbit in the vicinity of the field-null line. This mode is nonlinearly saturated as a result of the relaxation of current profile. Both the saturation level and the growth rate tend to increase as the ratio of the beam current to the plasma current I{sub b}/I{sub p} increases. It is also found that there is a threshold value of the beam velocity {upsilon}{sub b} {approx} {upsilon}{sub Ti} (ion thermal velocity) for the excitation of the instability. (author)
An integrated beam optics-nuclear processes framework is essential for accurate simulation of fragment separator beam dynamics. The code COSY INFINITY provides powerful differential algebraic methods for modeling and beam dynamics simulations in absence of beam-material interactions. However, these interactions are key for accurately simulating the dynamics of heavy ion fragmentation and fission. We have developed an extended version of the code that includes these interactions, and a set of new tools that allow efficient and accurate particle transport: by transfer map in vacuum and by Monte Carlo methods in materials. The new framework is presented, along with several examples from a preliminary layout of a fragment separator for a facility for rare isotope beams.
An nonlinear analysis of an annular beam propagating through a cylindrical waveguide in the presence of a helical wiggler and an axial guide field is presented. The analysis is based upon the ARACHNE simulation which is a non-wiggler-averaged slow-time-scale simulation code in which the electromagnetic field is represented as a superposition of the TE and TM modes in a vacuum waveguide, and the beam space-charge waves are represented as a superposition of Gould-Trivelpiece modes. The DC self-electric and self-magnetic fields are also included in the model. ARACHNE has been extensively benchmarked against experiments at MIT and NRL in the past with good agreement, but all of these experiments have dealt with solid electron beams and beam voltages in excess of 200 kV. In seeking to reduce the beam voltage requirements we now consider the effect of operation with an annular ...
The first long pulse production of high power D"- ion beams has been demonstrated in the JT-60 U negative ion sources, each of which was designed to produce 22 A, 500 keV D"- ion beams. Voltage holding capability and the grid power loading were examined for long pulse production of high power D"- ion beams. From the correlation between voltage holding and the light intensity of cathodoluminescence from the Fiber Reinforced Plastic insulators, the acceleration voltage for stable voltage holding capability was found to be less than 320-340 kV where the light was sufficiently suppressed. By tuning the extraction voltage, the grid power loadings in the ion sources were decreased to the allowable levels for long pulse injection without a significant reduction of the beam power. After tuning the acceleration and extraction voltages, D"- ion beams of 12.5 and 9.8 A were produced at 340 keV ...
A stiff skin forms on surface areas of a flat polydimethylsiloxane (PDMS) upon exposure to focused ion beam (FIB) leading to ordered surface wrinkles. By controlling the FIB fluence and area of exposure...Full Text Available
A simple device is described which is used to determine treatment distance and beam direction in electron therapy employing one collimation. A technique for the production of irregular field templates and localization films is given.
For very low collision energies electron capture from excited hydrogen by multicharged ions is characterized by enormous cross sections, the predicted maximum being comparable to the geometric size of the Rydberg atom. The ion-atom merged-beams technique is being used to study these collisions for the variety of charge states and the wide range of energies (0.1 to 1000 eV/amu) accessible to the apparatus. A neutral D beam containing a Rydberg atom population proportional to 1/n"3 is produced by collisional electron detachment of 8 keV D"- in N_2 gas. An applied electric field results in the range (n=24--11) depending on the strength of the field applied. This beam is then merged with O"3"+ or O"5"+ ion beams at low relative collision velocities where the resultant beam-beam signal of D"+ due to electron loss is dominated by electron capture. From the sharp decrease in the observed ...
The essential mechanical and electronic parts of a beam pulsing system are described, which reaches an energy resolution of ..delta..E/E=0.1%-0.4% in the energy range from 100 eV and 10 keV.
In view of poor local control rates obtained with standard treatment, intraoperative radiation (IORT) using electrons was combined with external beam irradiation and surgical resection, with or without...Full Text Available
A compact dedicated 3D breast SPECT-CT (mammotomography) system is currently under development. In its initial prototype, the cone-beam CT sub-system is restricted to a fixed-tilt circular rotation...Full Text Available
Relativistic electron beams are used for generating high power microwaves. These microwave sources require electron beam generators spanning significant ranges in voltage and impedance. The pulsed power technology used to generate these electron beams is presented. Electron beam generators that produce beams with pulse durations in the 10-ns to 100-ns regime consist of an energy-storage section, pulse-shaping section, and an electron beam diode. The energy-storage section is either a Marx generator or capacitor bank-pulsed transformer. The pulse shaping is done with high-voltage transmission lines. The electron beam diode is usually a cold-cathode, space-charge-limited flow device. For longer pulses (/approximately/1 ..mu..s) the energy storage and pulse chaping can be combined. Lumped-element pulse-forming networks (PFN) can be designed to ...
Relativistic electron beams are used for generating high power microwaves. These microwave sources require electron beam generators spanning significant ranges in voltage and impedance. The pulsed power technology used to generate these electron beams is presented. Electron beam generators that produce beams with pulse durations in the 10 ns to 100 ns regime consist of an energy storage section, pulse shaping section, and an electron beam diode. The energy storage section is either a Marx generator or capacitor bank-pulsed transformer. The pulse shaping is done with high-voltage transmission lines. The electron beam diode is usually a cold-cathode, space-charge-limited flow device. For longer pulses (approx.1 ..mu..s) the energy storage and pulse shaping can be combined. Lumped-element pulsed-forming networks (PFN) can be designed to produce ...
The localized Pt deposition on Si by 30 keV Ga"+ focused ion beam (FIB), 10 keV electron beam (EB) or dual beams (FIB and EB) using precursor gas has been compared by analysis using a 300 keV Be"2"+ microprobe with a beam spot size of 80 nm. The distribution of deposited Pt, Ga from the ion beam itself, and C from the precursor gas was obtained at and nearby the deposited areas by micro-RBS spectra and RBS mapping. All of the beam processed areas showed a uniform Pt distribution at the deposited areas. The amount of Pt atoms increased with the increase in ion or electron dose due to the decomposition of precursor gas. The thickness of Pt layer by EB is considerably less than that by FIB due to the reduced deposition rate. Ga atoms from the center of processed areas partly redeposited at and nearby the FIB processed areas within #approx#3 #mu#m. The Ga ...
In light beams with circular or elliptic polarization, the transverse energy flow consists of the "spin" and "orbital" parts. Both of them can induce the orbital motion of microparticles suspended within the field of a light beam, and this should be taken into account in experiments on the spin-to-orbital angular momentum conversion. The character of the spin, orbital and total transverse energy flows in circular Laguerre-Gaussian beams is studied analytically; graphical representations of the flows in the beam cross section (flow maps) are calculated and analyzed. The spin circulatory flow can be directed oppositely to the orbital one and/or to the polarization handedness. As a result, the total transverse energy circulation of a beam with homogeneous circular polarization can be of different handedness in different regions of the beam cross section, which are ...