UK PubMed Central (United Kingdom)

The effect of growth phase on expression of virulence-associated factors was studied by Northern hybridization in an M1T1 clinical isolate of Streptococcus pyogenes. Expression of M...Full Text Available

International Nuclear Information System (INIS)

Angelin Pedra is a specie found in the north of Mato Grosso State in Brazil, where an expressive volume of waste of this wood is produced. An alternative to recycle this waste is to produce wood plastic composites. However, structural and chemical investigations are fundamental to generate information for this use. In the present work, low field NMR was used to determine the spin-lattice and spin-spin relaxation times with objective to investigate the molecular dynamic behavior of the alburnu and cerne regions of Angelin Pedra aiming at a potential use of this waste wood in polymeric composites. The results of the proton spin-lattice relaxation time (T1H) and the proton spin-spin relaxation time (T2H) showed at least three different mobility domains for both regions. Among the values, one was very flexible and other was rigid. Knowing that wood is a polymer composite basically constituted by cellulose, hemicellulose and ...

Science.gov (United States)

Poncirin, flavanone glycoside, isolated from the fruit of Poncirus trifoliata, has anti-bacterial and anti-inflammatory activities. In this study, the effects of poncirin on the differentiation of mesenchymal stem cells were investigated. The C3H10T1/2 mesenchymal stem cells and primary bone marrow mesenchymal stem cells were studied. In the C3H10T1/2 cells, poncirin prevented adipocyte differentiation, as demonstrated by inhibition of cytoplasm lipid droplet accumulation and peroxisome proliferator-activating receptor-? (PPAR-?) and CCAAT-enhancer-binding protein-? (C/EBP-?) mRNA expression. By contrast, poncirin enhanced the expression of the key osteogenic transcription factors, runt-related transcription factor 2 (Runx2) and transcriptional coactivator with PDZ-binding motif (TAZ). Poncirin also enhanced expression of the osteogenic ...

UK PubMed Central (United Kingdom)

Vascular endothelial growth factor (VEGF) plays a critical role in normal development as well as retinal vasculature disease. During retinal vascularization, VEGF is most strongly expressed by not yet...Full Text Available

Science.gov (United States)

Abstract: Snake venom contains a number of small proteins,enzymes and other components,which displays a broad spectrum of biological activities. With the ability of specifically binding on acetylcholine acceptor, alpha-bungarotoxins are not only useful molecular probes in investigating the mechanism of neural signal transmission, but also potential pharmic preparations for neural disease treatment. In current research,cDNAs of Bungarus multicinutus venom gland were synthesized using SMART cDNA amplification kit and then, alpha-bungarotoxin genes were cloned and sequenced. Total of 20 clones were sequenced representing 14 isotoxin mRNAs of alpha-bungarotoxins. Among those clones, a novel isotoxin gene was subcloned into two expression plasmids, alpha-BgTX/pQE30a and alpha-BgTX/pGEX-4T-1, and transformed into E. coli. After inducing with IPTG, fused protein of GST-alpha-BgTX was successfully expressed at ...

British Library Electronic Table of Contents (United Kingdom)

In this context, the bulk ratio of CH4/N2 is examined as a potential alternative geochemical parameter for the assessment of thermal maturity of natural gas and compared to other previously published data. Open-system non-isothermal pyrolysis of low-mature coal from the Manjiaer sag, Tarim basin, yielded generation curves for methane and nitrogen. Analysis of the change of vitrinite reflectance indicates a two-stage process of thermal maturation with increasing temperatures. The relationship between Ro and pyrolysis temperature could be expressed by the following equations: Stage I: Ro = 0.0014T + 0.109, r = 0.9931(Ro Ro = 0.0067T -1.5855, r = 0.9996 (Ro > 0.6%). A kinetic interpretation of the characteristics of nitrogen and methane generation in humic coal during laboratory pyrolysis ind...

Energy Technology Data Exchange (ETDEWEB)

The use of cement based systems for solidification and stabilization of hazardous wastes has been proposed. The stabilization of Cr contaminated paint removal wastes in ordinary Portland cement and in a Portland cement and blast furnace slag matrix was investigated. A loading by volume of 75% waste and 25% cement (or cement + slag) was used. The expression of pore solution was utilized to determine the chemical environment encountered by the waste species in the cement matrix. The highly alkaline conditions of ordinary Portland cement determined the stability of the metal species, with Cr being highly soluble. The replacement of 25% of the Portland cement by blast furnace slag was found to decrease the [OH-] of the pore solution resulting in a decrease of the Cr concentration. For cement wastes forms hydrated for 28 days, the Cr concentration decreased in the expressed pore ...

International Nuclear Information System (INIS)

The purpose of this study is to develop a geometrically accurate imaging protocol at 3 T magnetic resonance imaging (MRI) for stereotactic radiosurgery (SRS) treatment planning. In order to achieve this purpose, a methodology is developed to investigate the geometric accuracy and stability of 3 T MRI for SRS in phantom and patient evaluations. Forty patients were enrolled on a prospective clinical trial. After frame placement prior to SRS, each patient underwent 3 T MRI after 1.5 T MRI and CT. MR imaging protocols included a T1-weighted gradient echo sequence and a T2-weighted spin echo sequence. Phantom imaging was performed on 3 T prior to patient imaging using the same set-up and imaging protocols. Geometric accuracy in patients and phantoms yielded comparable results for external fiducial reference deviations and internal landmarks between 3 T and 1.5 T MRI (mean ?0.6 mm; standard deviation ?0.3 mm). Mean stereotactic ...

International Nuclear Information System (INIS)

Synthesis genes encoding the human #alpha#- and #beta#-globin polypeptides have been expressed from a single operon in Escherichia coli. The #alpha#- and #beta#-globin polypeptides associate into soluble tetramers, incorporate heme, and accumulate to >5% of the total cellular protein. Purified recombinant hemoglobin has the correct stoichiometry of #alpha#- and #beta#-globin chains and contains a full complement of heme. Each globin chain also contains an additional methionine as an extension to the amino terminus. The recombinant hemoglobin has a C_4 reversed-phase HPLC profile essentially identical to that of human hemoglobin A_0 and comigrates with hemoglobin A_0 on SDS/PAGE. The visible spectrum and oxygen affinity are similar to that of native human hemoglobin A_0. The authors have also expressed the #alpha#- and #beta#-globin genes separately and found that the expression of the #alpha#-globin gene alone results in ...

British Library Electronic Table of Contents (United Kingdom)

Quantitative Real-Time PCR (qRT-PCR) is a widely used tool to study host responses against parasites. A crucial step in the gene quantification process is the normalization of the expression data against stable housekeeping genes (HKGs). However, in recent years, several reports have showed that the transcriptional levels of such HKGs can change dramatically, especially when cellular changes appear in the tissues investigated. The aim of the current study was to assess the variability of 11 putative HKGs in bovine abomasal tissue during an infection with the parasitic nematode Ostertagia ostertagi. Gene transcription levels of selected potential HKGs were measured by qRT-PCR and the expression stabilities evaluated using geNorm, NormFinder, and The Mann-Whitney-U test. The analysis showed ...

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The resistance to microbe damages of aqueous solutions of cutting fluids (SOZh), which contain dual and more complex mixtures of known compounds, is studied. Lauric acid, myristic and tridecanic acid give microbic resistance to the compositions of synthetic cutting fluids. A complexing of the compositions as a rule does not support precisely expressed effects of synergism or antagonism.

UK PubMed Central (United Kingdom)

BackgroundPulmonary vascular structure remodeling (PVSR) is a hallmark of pulmonary hypertension. P27^kip1, one of critical cyclin-dependent kinase inhibitors, has been...Full Text Available

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Spin-polarized liquid helium-3 is prepared by laser optical pumping in low magnetic field and at room temperature, prior to fast liquefaction of the polarized sample. The use of a new helium-3 cryostat enabled us to obtain liquid helium-3 with polarization rates up to 25 % at well-stabilized temperatures (around 0.5 K). We could thereby study the effect of nuclear polarization on liquid-vapour equilibrium, and particularly on the saturated vapour pressure. Very sensitive capacitive gauges were developed. We estimated (to first order in M{sup 2}) the expected effects when the polarization M is suddenly destroyed. These effects were experimentally observed in helium-3/helium-4 mixtures, in pure helium-3, only a transient increase in pressure has been recorded. We then describe in a third part a preliminary experiment which aimed at determining the longitudinal relaxation time T1 in mixtures. Relaxation on the walls is ...

British Library Electronic Table of Contents (United Kingdom)

Amyloid precursor protein (APP), a key protein in pathogenesis of Alzheimer's disease (AD), is a type I transmembrane protein which can be cleaved by b- and g-secretase to release the amyloidogenic b-amyloid peptides (Ab) and the APP intracellular domain (AICD). While Ab has been widely believed to initiate pathogenic cascades culminating AD, the physiological functions and regulations of AICD remain elusive. In present study, endogenous AICD was demonstrated to be increased by canonical Wnt signal. Instead of due to g-secretase activity, enhanced AICD expression was found due to the increased protein stability by Wnt/b-catenin. b-Catenin was demonstrated to be an associating partner of AICD, capable of promoting AICD mediated transcriptional activity. Investigation by AICD mutants proved ...

CERN Document Server

Charged particle beams in circular accelerators couple with their surroundings through induced electromagnetic fields. This interaction can be described by so-called coupling impedances. In the frequency domain the impedance in connection with the bunch spectrum allows for stability analysis and estimates. However, for simulation codes one usually needs the wakefunction, the equivalent of the impedance in time domain. Recently the transverse impedance of a cylindrical pipe with arbitrary surface impedance was given by L. Vos. An expression for the wakefunction of this transverse resistive wall impedance with inductive bypass is derived here.

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The herpes simplex virus type 1 thymidine kinase (HSV1-TK) reporter system is being used to directly and indirectly monitor therapeutic gene expression, immune cell trafficking and protein-protein interactions in various living animals. However, the issues of HSV1-TK enzyme stability in living cells and whether this reporter system is optimal for dynamic studies of gene expression events in genetic imaging have not be addressed. The purpose of the present study was to evaluate the application of this reporter system in dynamic studies of transcriptional gene regulation. To achieve this purpose, we established two tetracycline-inducible murine sarcoma cell lines, tetracycline-turn-off HSV1-tk-expressing cell line (NG4TL4/tet-off-HSV1-tk) and tetracycline-turn-off Luc-expressing cell line (NG4TL4/tet-off-Luc), to create an artificially regulated gene expression ...

International Nuclear Information System (INIS)

Portuguese 2010 p. 137-138 Brazil Preto, Monica S. de Moura Tavares,

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

International Nuclear Information System (INIS)

The active site of chicken gizzard myosin was labeled by direct photoaffinity labeling with ["3H]UDP. ["3H] UDP was stably trapped at the active site by addition of vanadate (Vi) and Co"2"+. The extraordinary stability of the myosin.Co2+.[3H]UDP.Vi complex (t1/2 greater than 5 days at 0 degrees C) allowed it to be purified free of extraneous ["3H]UDP before irradiation began. Upon UV irradiation, greater than 60% of the trapped ["3H]UDP was photoincorporated into the active site. Only the 200-kDa heavy chain was labeled, confirming earlier results using ["3H]UTP. Extensive tryptic digestion of photolabeled myosin subfragment 1 followed by high performance liquid chromatography separations and removal of nucleotide phosphates by treatment with alkaline phosphatase allowed two labeled peptides to be isolated. Sequencing of the labeled peptides and radioactive counting showed that Glu185 was the residue labeled. Since UDP is a ...

Environmental Research Database

ObjectivesThe overall objective is to establish rigorous and verified means of deploying FACTS devices as damping controllers so that stability limits of a congested grid can be expanded, with confidence, toward to the thermal limits. A key to this is to ensure that damping of oscillatory modes of the system are robust to the acknowledged variations of the system.~%~~%~The goals are:~%~~%~a) to apply model order reduction techniques to realistic grid systems and verify modes are adequately expressed,~%~~% [continued...]DescriptionTraditionally, the phenomena of inter-area oscillation between generation groups, e.g. England and Scotland, has been avoided through operating point constraints on tie-lines and acceptance of operation at less than thermal capacity. The need to support long distance trading makes such constraints unacceptable. Stability problems can be solved ...

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The onset of double-diffusive convection in a couple-stress fluid-saturated horizontal porous layer is studied using linear and weak nonlinear stability analyses. The modified Darcy equation that includes the time derivative term and the inertia term is used to model the momentum equation. The expressions for stationary, oscillatory and finite-amplitude Rayleigh number are obtained as a function of the governing parameters. The effect of couple-stress parameter, solute Rayleigh number, Vadasz number and diffusivity ratio on stationary, oscillatory and finite-amplitude convection is shown graphically. It is found that the couple-stress parameter and the solute Rayleigh number have a stabilizing effect on stationary, oscillatory and finite-amplitude convection. The diffusivity ratio has a destabilizing effect in the case of stationary and finite-amplitude modes, with a dual effect in the case of oscillatory convection. The ...

International Nuclear Information System (INIS)

Purpose: To assess the prognostic value of biologic (p53, Ki-67) and clinical factors in squamous cell carcinoma of the oropharynx after radical surgery and postoperative radiotherapy (RT). Methods and Materials: Between 1985 and 1995, a total of 102 patients with 104 tumor sites were entered onto the study. Fifty-five primary tumors (53%) involved the tonsils, 26 (25%) the soft palate, and 23 (22%) the base of the tongue. Median age was 53 years (range 36-80 years). The clinical T- and N-categories (UICC 1997) were: T1 (30), T2 (47), T3 (22), T4 (5), N0 (33), N1 (28), N2 (42), and N3 (1). Histologically-clear margins were achieved in all patients by initial surgery. Postoperative RT to the primary and regional lymphatics was given, to a total of 60 Gy in 6 weeks, and single daily fractions of 2 Gy. The expression of the nuclear p53- and Ki-67-labeling index (LI) was investigated by immunostaining using the monoclonal ...

International Nuclear Information System (INIS)

The point at which the common final pathway for induction of cancer by chemical carcinogens and ionizing radiation has not been identified. Although common molecular targets are suggested by recent findings about the role of oncogenes, the mechanism by which the deposition of radiation energy and the formation of adducts or other DNA lesions induced by chemicals affects the changes in the relevant targets may be quite different. The damage to DNA that plays no part in the transformation events, but that influences the stability of the genome, and therefore, the probability of subsequent changes that influence tumorigenesis may be more readily induced by some agents than others. Similarly, the degree of cytotoxic effects that disrupt tissue integrity and increase the probability of expression of initiated cells may be dependent on the type of carcinogen. Also, evidence was presented that repair of the initial lesions could be demonstrated after ...

Science.gov (United States)

It is shown that level-density expressions cannot adequately represent or substitute for level structure information when making calculations of the Hauser-Feshbach type for cross sections or isomer-ratios for nuclei in the first few MeV above their ground state. It is stated that such discrete level information should include both experimentally confirmed and theoretically predicted levels. The utility of discrete level information to optimize level density calculations, to compute isomer ratios, in deriving dipole strength functions, and in the analysis of primary gamma ray spectra is emphasized, especially for nuclei far from the line of stability. 29 refs., 12 figs., 6 tabs. (DWL)

British Library Electronic Table of Contents (United Kingdom)

Summary 1. Plants express multiple defensive traits, but little is known about the genetic stability and phenotypic plasticity of these traits in nature. To investigate sources of variation and their potential ecological consequences for herbivores, we combined field observations of cyanogenic lima bean with laboratory experiments. 2. Field studies in South Mexico revealed a distinct variability of cyanogenic traits within and among wild lima bean populations. To differentiate among genetic variation and the impact of ambient conditions on plant phenotypes, we used seed grown plants as well as clones propagated from high (HC) and low cyanogenic (LC) wild type plants. 3. In growth chamber experiments, we cultivated plants under three intensities each of drought and salt stress, nutrient sup...

UK PubMed Central (United Kingdom)

HIX, a recombinant derived from Moloney leukemia virus, has an envelope glycoprotein different from that of the Moloney virus. HIX and Moloney viruses share the majority of the large T1 oligonucleotides...Full Text Available

UK PubMed Central (United Kingdom)

The authors emphasize the importance of stability in biological standards and discuss the steps taken to ensure the stability of International Standards and the theoretical basis of the various stability...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The relationships between severity of iron deficiency anemia, response to iron treatment, respiratory and gastrointestinal illness and weight changes were assessed before (T1) and after (T2) iron therapy. Seventy-five pre-school children from rural Guatemala received daily oral iron (ferrous sulfate 5 mg/kg/day) for eleven weeks, and were classified into one of three groups: (1) severe iron deficient (Hgb < 9.25 g/dl at T1 and > 1g/dl Hgb response (T2-T1) to Fe Rx; (2) moderately iron deficient (Hgb 9.25 g/dl to 11.5 g/dl and T2-T1 > 1g/dl); (3) normal controls (Hgb > 11.5 g/dl and T2-T1 < 1g/dl). When both severely and moderately anemic children were pooled together, there was a statistical significant difference between the number of days ill with ...

Energy Technology Data Exchange (ETDEWEB)

Nuclear magnetic resonance (NMR) images of live rats with sterile and pyogenic abscesses, hematomas, and various implanted and spontaneous neoplasms demonstrated good contrast differentiation between pathologic and surrounding normal tissues. This differentiation was maximal when both the T1 and T2 tissue relaxation times were used as criteria. Neoplasms have a broad range of T1 and T2 values and may be confused with abscesses or hematomas. Tissue rate constants (1/T1 and 1/T2) are mainly dependent on total water content, the exception being fat, which has a 1/T2 value much shorter than that expected on the basis of water content alone.

UK PubMed Central (United Kingdom)

Pseudomonas putida encodes 20 extracytoplasmic sigma factors (ECFs). In this study, we show that one of these ECFs, known as ECF-Pp12...Full Text Available

UK PubMed Central (United Kingdom)

ObjectiveTo examine the longitudinal relationship between depressive symptoms at study entry (T1) on pain intensity (PI) and functional disability over a 1-year period...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

Some kind of one-dimensional (1D) peanut-shaped fullerene polymers (PSFPs) exhibit metallic properties, but their occurrence conditions are not yet clarified. By using the VASP (Vienna ab-initio simulation package) with density functional theory (DFT) and projector augmented wave (PAW) method, we have performed first-principles electronic structure calculations of four basic 1D PSFPs, T1, T2, T6, and T7 (the name of T1-T6 is the same as that of Wang et al. [9]) and two associated 1D PSFPs, T1SW1 and T6SW that are created by generalized Stone-Wales transformation (GSW) from T1 and T6. We found that almost regular six-membered rings connected throughout the tube are necessary to get metallic properties for the 1D PSFPs, although there may be several other conditions to expect metallic proper...

Science.gov (United States)

Jul 16, 2011 ... The standard filtering applies to all the existing distribution methods/media. ... needed to allow your data point(s) to be added to the MOA lightcurve. .... name="t1" value="0.00" unit="sigma" ucd="stat.snr" />

International Nuclear Information System (INIS)

Purpose: Patients with mycosis fungoides [cutaneous T-cell lymphoma (CTCL)] may benefit from adjuvant therapy after completing total skin electron beam therapy (TSEBT). We report the results for (T1(T2)) CTCL patients treated with adjuvant oral psoralen plus ultraviolet light (PUVA) with respect to overall survival (OS), disease-free survival (DFS), salvage of recurrence, and toxicity. Methods and Materials: Between 1974 and 1993, TSEBT was administered to a total of 213 patients with CTCL. Records were reviewed retrospectively, and a total of 114 patients were identified as having T1 or T2 disease. Radiotherapy was provided via a 6-MeV linac to a total of 36 Gy, 1 Gy/day, 4 days/week, for 9 weeks. Beginning in 1988, patients were offered adjuvant PUVA within 2 months of completing TSEBT. This was started at 0.5-2 J/m"2, 1-2 treatments/week, with a taper over 3-6 months. Therapy then continued once per ...

International Nuclear Information System (INIS)

The authors compared unenhanced and contrast-enhanced fast MRI and Computerized Tomography in the detection of liver metastases. Eleven patients with single or multiple hepatic lesions (42 in all) were submitted to V and magnetic resonance studies; T1- and T2- weighted TSE, T2-weighted TSE with fat suppression, unenhanced breath-hold TFE and early or delayed enhanced breath-hold TFE images were acquired with a 1.5 T superconductive magnet (Philips NT). The quantitative analysis of all magnetic resonance images was performed for contrast/noise ratio (CNR) and number of detected lesions; magnetic resonance and Computerized Tomography images were also compared qualitatively for lesion conspicuity, anatomical structure identification and artifacts. The results were compared with Student's test. Early enhanced breath-hold TFE was statistically superior to T1-weighted TSE (p = .0009), T2-weighted TSE (p = ...

KoreaScience (Korea)

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Science.gov (United States)

Escherichia coli spheroplast protein y (EcSpy) is a small periplasmic protein that is homologous with CpxP, an inhibitor of the extracytoplasmic stress response. Stress conditions such as spheroplast formation induce the expression of Spy via the Cpx or the Bae two-component systems in E. coli, though the function of Spy is unknown. Here, we report the crystal structure of EcSpy, which reveals a long kinked hairpin-like structure of four ?-helices that form an antiparallel dimer. The dimer contains a curved oval shape with a highly positively charged concave surface that may function as a ligand binding site. Sequence analysis reveals that Spy is highly conserved over the Enterobacteriaceae family. Notably, three conserved regions that contain identical residues and two LTxxQ motifs are placed at the horizontal end of the dimer structure, stabilizing the overall fold. CpxP also contains the conserved sequence motifs and has a predicted ...

Czech Academy of Sciences Repository

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Science.gov (United States)

No abstract available.

Science.gov (United States)

This study examined the effect of sulfur-containing compounds on the storage stability of Jet A

Science.gov (United States)

Since August 2000, the stock market in the USA as well as most other western markets have depreciated almost in synchrony according to complex patterns of drops and local rebounds. In (Quantitative Finance 2 (2002) 468), we have proposed to describe this phenomenon using the concept of a log-periodic power law antibubble, characterizing behavioral herding between investors leading to a competition between positive and negative feedbacks in the pricing process. A monthly prediction for the future evolution of the US S&P 500 index has been issued, monitored and updated in (http://www.ess.ucla.edu/faculty/sornette/prediction/index.asp#prediction), which is still running as the article goes to press. Here, we test the possible existence of a regime switching in the US S&P 500 antibubble. First, we find some evidence that the antibubble has exhibited a transition in log-periodicity described by a so-called second-order log-periodicity. Second, we develop a battery of tests to ...

Science.gov (United States)

Two plasmids which express either nearly intact or truncated filamentous hemagglutinin (FHA) from Bordetella pertussis and which are marked with a tetracycline resistance (Tcr) gene were transformed into Salmonella dublin SL1438, an aroA deletion mutant intended for use as an attenuated oral vaccine against salmonellosis. These S. dublin recombinants, when fed to mice, induced serum immunoglobulin, immunoglobulin M (IgM), and sometimes IgA antibody responses to FHA and S. dublin. In addition, IgA antibodies against FHA were found in gut wash fluids. S. dublin carrying pDB2300, a multicopy plasmid encoding truncated FHA protein, induced a better antibody response than did S. dublin carrying pDB2000, a low-copy-number plasmid encoding full-sized FHA. Administration of tetracycline to mice enhanced the stability of recombinant plasmids, and tetracycline-treated mice developed higher anti-FHA titers. Although neither strain examined is suitable for ...

International Nuclear Information System (INIS)

Coronary angiography provides anatomical information whereas thellium myocardial scintigraphy measures resistive tissue perfusion. Because of this fundamental difference. The authors question the validity of using coronary angiography as the gold standard to judge thellium myocardial scintigraphy. The authors studied 20 patients undergoing elective percutaneous coronary angioplasty who fulfilled the following criteria: (1) history of chest pain; (2) angiographically significant single vessel disease (>50% stenosis); (3) no prior myocardial infarction. All patients underwent maximal exercise thallium single photon emission computed tomography (T1-SPECT). Tl-SPECT was scored visually according to a 0 to 3 scale (0=absent uptake; 1=markedly decreased uptake; 2=minimally decreased uptake; 3=normal uptake). Translesional gradient and percent stenosis were measured before and after angioplasty. The authors found that significant linear ...

Energy Technology Data Exchange (ETDEWEB)

We have been investigating radiation-induced neoplastic transformants of C3H 10T1/2 mouse fibroblasts for evidence of heritable changes. C3H 10T1/2 cells were treated with 8 Gy X rays. After approximately 8 weeks of culture, type II/III foci were isolated from the monolayer using cloning rings. Cell lines developed from these foci, and clones established from these cell lines, were examined for DNA content. The isolated focus-derived populations and derived clones often display aneuploidy and/or polyploidization. In one instance a clone (derived from a single cell) displayed multiple polyploidies. During passage the ploidy of many of the anomalous populations gradually reverted to the ploidy of the non-neoplastically transformed state. The morphological features associated with the neoplastic transformation event were nevertheless retained. The results demonstrate that exposure to radiation can induce, ...

International Nuclear Information System (INIS)

Four "1"2"5I labeled mono- and diamines were prepared and evaluated as potential brain-imaging agents. The diamines are analogues of the previously reported "7"5Se labeled diamines, which show high brain uptake and retention. All of the radioiodinated amines display high initial brain uptake in rats after intravenous injection (1.7-2.4% dose/organ). The xylylenediamines show prolonged brain retention (t1/2 approximately 18 h), which is desirable for brain imaging. In contrast, the benzylamine is rapidly cleared from brain tissue (t1/2 approximately 15 min).

Energy Technology Data Exchange (ETDEWEB)

In this paper the concept of a composite power system stabilizer is investigated. This stabilizer comprises a properly designed, robust, conventional power system stabilizer (CPSS) and an auxiliary stabilizer (AS) which can be either a self-tuning stabilizer (ASTS) or a fixed-parameter stabilizer (AFPS). For small disturbances, the CPSS performs satisfactorily over a wide range of operating conditions. When large disturbances occur the auxiliary stabilizer augments the performance of the CPSS. It has been demonstrated that the composite power system stabilizer can significantly improve the dynamic performance of the system when there is a major disturbance such as a short circuit in the system. Because in the case of a single-machine system the parameters of the ASTS do not vary appreciably, it can also be implemented as ...

UK PubMed Central (United Kingdom)

Synthetic gene networks can be used to control gene expression and cellular phenotypes in a variety of applications. In many instances, however, such networks can behave unreliably due to gene expression...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundCells dynamically adapt their gene expression patterns in response to various stimuli. This response is orchestrated into a number of gene expression modules consisting...Full Text Available

UK PubMed Central (United Kingdom)

The protein kinase CK2 (formerly casein kinase II) is thought to be involved in light-regulated gene expression in plants because...Full Text Available

UK PubMed Central (United Kingdom)

The aim of this study was to survey the expression of an embryonic cytokine gene, MK, in the normal organs and neoplastic tissues of adults. Northern analysis showed that MK mRNA was exclusively expressed...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Recent topics in the theoretical magnetohydrodynamic (MHD) analysis in the heliotron configuration are overviewed. Particularly, properties of three-dimensional equilibria, stability boundary of the interchange mode, effects of the net toroidal current including the bootstrap current and the ballooning mode stability are focused. (author)

UK PubMed Central (United Kingdom)

Gene expression is a fundamentally stochastic process, with randomness in transcription and translation leading to significant cell-to-cell variations in mRNA and protein levels. This variation...Full Text Available

UK PubMed Central (United Kingdom)

HypothesisBiomarkers, commonly expressed in breast cancer cells, may be correlated with their expression in breast skin of the same subjects.MethodsThe...Full Text Available

Science.gov (United States)

... Title : ERG Expression Levels in Prostate Tumors Reflect Functional Status of the Androgen Receptor (AR) as a Consequence of Fusion of ERG ...

Science.gov (United States)

The pressure of a 6:12 fluid is obtained from the Percus-Yevick theory at the temperature kT/? = 1.35. The energy equation results are in excellent agreement with machine calculation results in contrast to the pressure and compressibility equation results. Present address: Diffusion Research Unit, The Australian National University, Canberra, ACT, Australia.

Energy Technology Data Exchange (ETDEWEB)

The volume contains reports on plant technology, on systems organisation with the aim to minimize the risk (human error), on the problem of seismic risk, on core-disruptive accidents and on accident consequence models with different release categories and a comparison of the potential damage incurred. Mr. Webb; one of the authors, attempts to disprove the objections to his two earliest SNR statements by experts of Karlsruhe Nuclear Research Centre.

Energy Technology Data Exchange (ETDEWEB)

Lipiodol Ultra-Fluid (Lipiodol) is widely applied in the transcatheter arterial embolization (TAE). We studied signal intensity, the T1 relaxation time and the T2 relaxation time of Lipiodol itself using Siemens Magnetom H15-2 T (1.5 Tesla) and Magnetom M10 (1.0 Tesla). Lipiodol showed higher signal intensity than saline solution on the T1-weighted images (short TR, short TE technique in spin echo method). On the T2-weighted images (long TR, long TE technique in spin echo method), Lipiodol showed lower signal intensity than saline solution. The T1 relaxation time of Lipiodol, measured at 1.0 T, was 201 msec and 218 msec at 1.5 T. The T2 relaxation time of Lipiodol, measured at 1.0 T, was 127 msec; and 167 msec at 1.5 T. The signal intensity of Lipiodol at 1.0 T was higher than the intensity at 1.5 T. Shorter T1 ...

Science.gov (United States)

... Accession Number : ADD109273. Title : THERMAL STABILITY OF ALPHA-BETA TITANIUM ALLOY Ti-5Al-2Cr-1Fe,. Corporate Author : ...

Energy Technology Data Exchange (ETDEWEB)

This paper presents a practical design for a power system stabilizer using the differential geometric linearization approach. This stabilizer uses the information at the secondary bus of the step-up transformer as input signals, enabling its application to multi-machine power systems. The stabilizer makes it possible to obtain all necessary information within its own power station without observing an equivalent reactance in other power systems. To evaluate the dynamic performance of this stabilizer, the authors tested it on a multi-machine system model using the computer. The simulation results showed that the stabilizer offered good dynamic performance and robustness compared with conventional power system stabilizers, thus confirming its very effective and practical application in power system stabilization.

Science.gov (United States)

Two hundred eleven references from the period 1951 to 1978 are reviewed in this survey of literature on the thermal stability of jet aircraft fuels.

Energy Technology Data Exchange (ETDEWEB)

A technique for designing an adaptive power system stabilizer is presented which improves the dynamic stability of power systems by effectively increasing the damping torque of the synchronous generator in the system. The proposed adaptive stabilizer is optimal in the sense of minimizing a specified performance condition. A characteristic feature of using a Lyapunov techniques is that it leads to stable adaptation loops. The dynamic responses following a step disturbance by digital simulations are obtained by means of three types of stabilizers: the conventional power system stabilizer, a frequency-response-based optimal adaptive stabilizer and the proposed Lyapunov stabilizer. Simulation results on a typical single-machine/infinite-bus system illustrate the superiority of the proposed technique. (author).

Science.gov (United States)

PMID:21331648

KoreaScience (Korea)

Full Text Available

DEFF Research Database (Denmark)

Udgivelsesdato: 1991-null

DEFF Research Database (Denmark)

development, histochemical, human, malformation, p63 gene, tooth

International Nuclear Information System (INIS)

Published in summary form only.

KoreaScience (Korea)

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KoreaScience (Korea)

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Energy Technology Data Exchange (ETDEWEB)

A copyrighted computational fluid dynamics computer code, ICOMFLO, has been developed for the simulation of multiphase reacting flows. The code solves conservation equations for gaseous species and droplets (or solid particles) of various sizes. General conservation laws, expressed by elliptic type partial differential equations, are used in conjunction with rate equations governing the mass, momentum, enthalpy, species, turbulent kinetic energy, and turbulent dissipation. Associated phenomenological submodels of the code include integral combustion, two parameter turbulence, particle evaporation, and interfacial submodels. A newly developed integral combustion submodel replacing an Arrhenius type differential reaction submodel has been implemented to improve numerical convergence and enhance numerical stability. A two parameter turbulence submodel is modified for both gas and solid phases. An evaporation submodel treats not only droplet ...

KoreaScience (Korea)

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KoreaScience (Korea)

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KoreaScience (Korea)

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A process is claimed for stabilizing fuels during storage by blending therewith oxalic acid derivatives of mono- or bis-succinimides of polyalkylpolyamines. The fuels are stabilized by the presence of 10 to 100 parts per thousand barrels of these oxamides. For particular applications mixtures of monoand bis-succinimides in varying proportions can be used.

Science.gov (United States)

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This paper describes the implementations of a fuzzy logic based self-tuned controller to improve the stability of electric power systems. The stabilizing signal is computed using the standard fuzzy membership function depending on the speed/acceleration state of the generator in the phase plane. The performance of the proposed stabilizer is demonstrated by practical implementation using a digital signal processor mounted on a PC-AT. Results of the experimental tests on a physical model of a power system are presented.

KoreaScience (Korea)

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KoreaScience (Korea)

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KoreaScience (Korea)

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Energy Technology Data Exchange (ETDEWEB)

The paper presents a sequential procedure for coordinated stabilization of a multimachine power system with arbitrary complexity of the system model. The most effective machine to be equipped with a power system stabilizer is identified using eigenvalue analysis. The selection is based on the sensitivity of critical eigenvalues to increases in the coefficient of a damping term which is inserted in each equation of motion, in succession. The method is applied to a three-machine system and simulation studies show appreciable improvements in the small disturbance stability of the system.

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Slope stability can be a major problem during the construction of surface facilities. Cutting into existing ground disturbs the mechanics of the surrounding area, which can result in landslides and rock falls. This practical reference gives you the comprehensive information you need for slope stability analysis, suitable methods of analysis with and without the use of computers, and examples of common stability problems and stabilization methods for cuts and fills. It includes detailed discussions of methods used in slope stability analysis, including the Ordinary Method of Slices, Simplified Janbu Method, Simplified Bishop Method, Spencer`s Method, other limit equilibrium methods, numerical methods, total stress analysis, effective stress analysis, and the use of computer programs to solve problems. Chapters include: General Slope Stability Concepts; ...

Energy Technology Data Exchange (ETDEWEB)

The damping of unwanted oscillations in the generator units after a failure can be realized by installing a stabilizer between f.e. the revs of the generator and an input of the voltage regulator. The tuning of a Power System Stabilizer (PSS) is investigated using bode plots. Eigenvalue analysis shows an enlarged system stability margin. The method was tested on an advanced analogue power system simulator. As a result of these tests it appears to be useful to consider the stability as well as the optimal tuning. 5 figs., 6 refs.

Energy Technology Data Exchange (ETDEWEB)

A thermal-resistant radiation sensing system using optical fiber has been developed. The system is for monitoring progress of chemical decontamination and able to measure the gamma-ray level in a hot solution of decontamination chemicals in situ. Our sensor head makes use of thermal-resistant NaI (T1) and it is connected to an optical fiber bundle. Scintillation photons pass from the NaI (T1) into the end of the bundle. This part of the system can withstand temperatures of over 100degC. At the far end of the optical fiber bundle, the scintillation photons are converted into fluorescent photons using a wavelength-shifting fiber. These photons are transferred to a distant photomultiplier tube through two thin transparent optical fibers. Furthermore, we propose a self-compensation technique for the dependence of scintillator sensitivity on. This compensation method is based on the correlation between ...

International Nuclear Information System (INIS)

The half-life of "1"0"9Cd was measured by following the decay of sources from a radiochemically pure solution with two different measuring systems: an ionisation chamber and a high-purity germanium (HPGe) detector. The measurements were performed over a period of 3.6 years, i.e. about 2.8 half-lives of "1"0"9Cd. The resulting half-life values and detailed uncertainty budgets (k=1) are presented for both systems. The result obtained with the ionisation chamber, 462.36 (33) days, and the one obtained with the HPGe detector, 461.92 (76) days, are mutually consistent. The weighted mean of our measured values, T_1_/_2("1"0"9Cd)=462.29 (30) days, is consistent with the currently recommended values of 461.4 (12) days and 462.0 (3) days. From a set of selected experimental values published after 1970, a 'partially weighted mean' of T_1_/_2("1"0"9Cd)=462.36 (39) days was calculated. More measurements are needed ...

International Nuclear Information System (INIS)

The MRI and CT appearances in 48 patients with histologically confirmed benign and malignant pleural abnormalities were compared retrospectively. Abnormal pleural changes were shown in 47 out of the 48 patients by high signal intensity of the pleura in T_2-weighted sequences and in contrast enhanced T_1-weighted sequences on MRI. CT showed abnormalities in 45 out of 48 patients. Delineation of pleural and pulmonary changes by CT was possible in 13 out of 23 cases, and pleural disease from effusions in 15 out of 28 cases. T_2-weighted MRI was successful in 14 out of 23 and 4 out of 28 cases, respectively. T_1-weighted images after contrast were successful in 20 out of 23 and 22 out of 28 cases, respectively. Indications of malignant pleural disease were the presence of mediastinal or circumferential involvement or involvement of the entire pleura, thickness of more than 10 mm and nodular changes. The ...

International Nuclear Information System (INIS)

The primary aim was to evaluate delayed contrast-enhanced MRI in depicting perineural spread of hilar cholangiocarcinoma (CCC) and consequently to determine the capability of MRI/MRCP for staging CCC. Fifteen patients that underwent MRI/MRCP and surgical treatment were retrospectively included. Two radiologists evaluated MR images to assess delayed periductal enhancement, extent of bile duct stenosis, liver parenchymal and vascular involvement and presence of liver atrophy. An agreement between delayed enhancement of the bile duct walls and perineural neoplastic spread showed a very good correlation factor (0.93). The overall accuracy in detecting biliary neoplastic invasion was higher for delayed T1-weighted images (93.3%) than for the MRCP images (80%), and T1-delayed image increased the MR accuracy in assessing the neoplastic resectability (p < 0.05). MRI correctly predicted vascular involvement ...

International Nuclear Information System (INIS)

Between 1984 and 1988, seven women with breast cancer were treated with intraoperative electron beam therapy (IOEBT). All patients were Caucasian. Patient age ranged from 37 to 62 (median 53) years. Histopathology was infiltrating duct carcinoma (6/7) or medullary carcinoma (1/7). Four tumors were staged T1 N0 MO, one T1 N1 MO, one T2 N1 MO, and one lesion was recurrent. At the time of primary lumpectomy or axillary node dissection, a dose of 10 or 15 Gy IOEBT was administered to the tumor bed with 6 or 9 MeV electrons through the lumpectomy wound. All patients received 45 or 50 Gy over five to six weeks with 6 MV photons to the breast and, in four patients, to the regional nodes. Three patients received adjuvant chemotherapy and tamoxifen. No post-operative complications were observed. All patients are alive as of August, 1989, with no evidence of recurrent disease. Excellent cosmesis is the rule. ...

British Library Electronic Table of Contents (United Kingdom)

Abstract Aims: This study performed a systematic review and meta-analysis on glycemic control and pregnancy outcomes in women with type 1 diabetes mellitus (T1DM) treated with lispro (LP) versus regular insulin (RI) since before pregnancy. Methods: We performed a MEDLINE and EMBASE search. Abstracts (and full articles when appropriate) were reviewed by two independent researchers. Inclusion criteria were patients with T1DM, data on women treated with RI and LP since before pregnancy until delivery in the same article, at least five pregnancies in each group, and information on at least one pregnancy outcome. Quality assessment was performed using the Newcastle?Ottawa Quality Assessment Scale for cohort studies. Results: Outcome data were summarized with Revman version 5.0 (ims.cochrane.org...

Energy Technology Data Exchange (ETDEWEB)

This report contains two sections. In the first section a limited review is presented and the preparation of the red mud based additives is described. The additives are characterized by composition and their catalytic activity in hydrocracking is investigated in a batch autoclave under an initial hydrogen pressure of 12 MPa at 435 C and 30 min residence time. A quantitative characterization of the products is given. Comparisons between the red mud additives and coke respectively a commercial catalyst are made. (orig.)

Energy Technology Data Exchange (ETDEWEB)

Objective: To compare the histopathology of nodular fasciitis (NF) with the magnetic resonance imaging (MRI) findings in order to evaluate the basis of the MR signal characteristics. Design and patients: Ten patients with NF, nine females and 1 male, with an age ranging from 13 to 58 years (mean 26.8 years) were studied. MRI findings, available in all 10 patients, were compared with the histopathology in nine patients, and an area-to-area comparative study of the whole specimen section histopathology and MRI was performed in two patients. Results: On the basis of an excisional biopsy or resection specimen, the nine lesions were classified into myxoid (n=4), cellular (n=3) and fibrous (n=2) subtypes. Four myxoid lesions with a subcutaneous location showed a homogeneous SI comparable with muscle on T1-weighted images, high SI on T2-weighted images, and had homogeneous enhancement. One cellular lesion presented with homogeneous, slightly higher SI ...

Energy Technology Data Exchange (ETDEWEB)

The central nervous system is involved in 10-20% of cases in Lyme disease. The neurological symptoms, time course of the disease and imaging findings are multifaceted. We report two patients with cervical radiculitis. Magnetic resonance imaging revealed strong enhancement of the cervical nerve roots on contrast-enhanced T1-weighted images. These imaging patterns of borrelia-associated radiculitis have not been reported before. Knowledge of these imaging features may help to diagnose neuroborreliosis, which presents with non-specific symptoms. (orig.)

British Library Electronic Table of Contents (United Kingdom)

Magnetic resonance (MR) imaging and histopathology were used to diagnose an articular process synovial myxoma in a dog. On MR images, the tumor was characterized by distortion of the left L1-L2 articular process, widening of the articular process joint, and the presence of a mass contiguous with the synovium of the articular process that displaced the spinal cord. The tumor was T2-hyperintense, T1-hypointense, relative to muscle, and had mild contrast enhancement. The MR features of articular process synovial myxoma may be distinct from other diseases of the articular process joint.

International Nuclear Information System (INIS)

In Nuclear Magnetic Resonance (NMR) imaging, contrast is dependent on the emission of radiofrequency waves by atomic nuclei, balanced by several parameters. The high information content of NMR images is due to the multiplicity of its parameters. However, this advantage introduces a difficulty in the interpretation of the contrast. There are three contrast parameters for each tissue: hydrogen nuclei density; relaxation time T1; relaxation time T2. Contrast may be enhanced towards any of these parameters by increasing the emission of radiowaves by atomic nuclei using particular pulse sequences.

British Library Electronic Table of Contents (United Kingdom)

Phospholipase D (PLD) has been recognized as a regulator of cell proliferation and tumorigenesis, but little is known about the molecules regulating PLD expression. Thus, the identification of small molecules inhibiting PLD expression would be an important advance in PLD-mediated physiology. Quercetin, a ubiquitous bioactive flavonoid, is known to inhibit proliferation and induce apoptosis in a variety of cancer cells. In the present study, we examined the effect of quercetin on the expression of PLD in U87 glioma cells. Quercetin significantly suppressed the expression of PLD1 at the transcriptional level. Moreover, quercetin abolished the protein expression of PLD1 in a time and dose-dependent manner, as well as inhibited PLD activity. Quercetin suppressed NFkB-induced PLD1 expression vi...

UK PubMed Central (United Kingdom)

Earlier we have shown that exogenous expression of HIPPI, a molecular partner of Huntingtin interacting protein HIP-1, induces apoptosis and increases expression of caspases-1, -8 and -10 in HeLa and...Full Text Available

UK PubMed Central (United Kingdom)

Many of the gene products that participate in nitrogen metabolism are sensitive to nitrogen catabolite repression (NCR), i.e., their expression is decreased to low levels when readily used nitrogen...Full Text Available

UK PubMed Central (United Kingdom)

In rats, expression of the immediate early gene, c-fos observed in the brain following male copulatory behavior relates mostly to the detection of olfactory information originating...Full Text Available

UK PubMed Central (United Kingdom)

alpha-actinins are actin microfilament crosslinking proteins. Vertebrate actinins fall into two classes: the broadly-expressed actinins 1 and 4 (actn1 and actn4)...Full Text Available

UK PubMed Central (United Kingdom)

Previous studies have been conducted in gene expression profiling to identify groups of genes that characterize the colorectal carcinoma disease. Despite the success of previous attempts to identify...Full Text Available

UK PubMed Central (United Kingdom)

Sensory neurons in aging mammals undergo changes in anatomy, physiology and gene expression that correlate with reduced sensory perception. In this study we compared young and aged mice to identify...Full Text Available

UK PubMed Central (United Kingdom)

Increased intrauterine prostaglandin (PG) production is crucial for the initiation of parturition. To investigate the mechanisms controlling intrauterine PG synthesis, we examined the expression of...Full Text Available

UK PubMed Central (United Kingdom)

Expressed emotion measures, encompassing dimensions of criticism (CRIT), and emotional overinvolvement (EOI) are increasingly being used to assess the parent–child relationship in child...Full Text Available

UK PubMed Central (United Kingdom)

The ability to achieve tumor selective expression of therapeutic genes is an area that needs improvement for cancer gene therapy to be successful. One approach to address this is through the...Full Text Available

UK PubMed Central (United Kingdom)

Male transgenic mice expressing the polyomavirus middle T (PyV-MT) gene exhibited growth and developmental abnormalities in prostatic and other urogenital epithelium. Expression of PyV-MT was directed...Full Text Available

UK PubMed Central (United Kingdom)

AimsThe aims of the study were to study the effect of pre-operative treatment on the expression of tumour-related proteins and to correlate the expression of these...Full Text Available

UK PubMed Central (United Kingdom)

AbstractIntrathymic expression of tissue-restricted antigens (TRAs) has been viewed as the key element in the induction of central tolerance and recently, a central role for the autoimmune...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundGene expression profiling and the analysis of protein-protein interaction (PPI) networks may support the identification of disease bio-markers and potential drug targets....Full Text Available

UK PubMed Central (United Kingdom)

The aim of the present study was to identify specific behavioral patterns that contribute to diminished estrus expression in lame cows. Behavioral scan and focal sampling were used to examine...Full Text Available

UK PubMed Central (United Kingdom)

Exploring the possibility of enhancing the properties of baculoviruses as biological control agents of insect pests, we tested the effect of expressing an insect gene (jhe) encoding juvenile hormone...Full Text Available

UK PubMed Central (United Kingdom)

To gain insight into ATP-binding cassette transporter A1 (ABCA1) function and its potential role in AD pathology, we analyzed the expression of the cholesterol transporter ABCA1...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundASCL1 role in pancreatic endocrine tumourigenesis has not been established. Recently it was suggested that ASCL1 negatively controls expression of the...Full Text Available

UK PubMed Central (United Kingdom)

Optimal sample handling techniques for tissue preparation and storage, RNA extraction and quantification, and target gene detection are crucial for reliable gene expression analysis. Methods...Full Text Available

UK PubMed Central (United Kingdom)

The availability of full genome sequences has allowed the construction of microarrays, with which screening of the full genome for changes in gene expression is possible. This method can provide a wealth...Full Text Available

UK PubMed Central (United Kingdom)

Human endometrium resists embryo implantation except during the 'window of receptivity'. A change in endometrial gene expression is required for the development of receptivity. Uterine calbindin-D28k...Full Text Available

UK PubMed Central (United Kingdom)

To study the expression of Fc receptors in human alveolar macrophages (AM), the cells were collected from 12 healthy controls and 22 patients with sarcoidosis and the activity involved in binding to...Full Text Available

UK PubMed Central (United Kingdom)

Zygotes of fucoid algae have long been studied as a paradigm for cell polarity. Polarity is established early in the first cell cycle and is then expressed as localized growth and invariant cell division....Full Text Available

UK PubMed Central (United Kingdom)

We developed mice with germline endogenous expression of oncogenic Hras to study effects on development and mechanisms of tumor initiation. They had high perinatal mortality, abnormal...Full Text Available

UK PubMed Central (United Kingdom)

Normal mouse epidermis constitutively expresses prostaglandin-H synthase 1 (PGHS-1) but no PGHS-2. Acute inflammation and epidermal hyperplasia, (hyperplastic transformation), as evoked in adult mouse...Full Text Available

UK PubMed Central (United Kingdom)

Systemic administration of lipopolysaccharide (LPS), which causes endotoxemia and systemic inflammation, has been reported to induce expression of the gene for type II inducible nitric oxide synthase...Full Text Available

UK PubMed Central (United Kingdom)

Lymphocytes from patients with insulin-dependent diabetes mellitus (IDDM), a chronic autoimmune disease, have recently been shown to have decreased surface expression of MHC class I antigens. Since...Full Text Available

UK PubMed Central (United Kingdom)

Histone Arg methylation and Lys acetylation have been found to cooperatively regulate the expression of p53 target genes. Peptidylarginine deiminase 4 (PAD4) is an enzyme that citrullinates...Full Text Available

UK PubMed Central (United Kingdom)

AIM: To investigate the relation of Fas and Fas ligand (FasL) protein expression with carcinogenesis and metastasis of gastric carcinoma.METHODS: Immunohistochemistry was used to detect Fas and...Full Text Available

UK PubMed Central (United Kingdom)

The human CYP3A subfamily is of interest due to its multiplicity, activity toward known carcinogens, and extrahepatic expression. In situ hybridisation analysis of formalin fixed, routinely processed...Full Text Available

UK PubMed Central (United Kingdom)

Antisense radiopharmaceuticals could be used to image gene expression in the brain in vivo, should these polar molecules be made transportable through the blood–brain barrier....Full Text Available

UK PubMed Central (United Kingdom)

BackgroundGATA-2 is a transcription factor required for hematopoietic stem cell survival as well as for neuronal development in vertebrates. It has been shown that specific expression...Full Text Available

UK PubMed Central (United Kingdom)

Flying insects use visual cues to stabilize their heading in a wind stream. Many animals additionally track odors carried in the wind. As such, visual stabilization of upwind tracking directly aids...Full Text Available

UK PubMed Central (United Kingdom)

The stability of prothrombin and factor VII was studied using accelerated degradation tests in three preparations of freeze-dried pooled normal plasmas. In a previous report (Brozović, Gurd,...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

This report presents geologic considerations that are pertinent to the Remedial Action Plan for Slick Rock mill tailings. Topics covered include regional geology, site geology, geologic stability, and geologic suitability.

UK PubMed Central (United Kingdom)

The exposure of cells to several metal ions stabilizes HIF-1α protein. However, the molecular mechanisms are not completely understood. They may involve inhibition of hydroxylation by either...Full Text Available

UK PubMed Central (United Kingdom)

One selection pressure shaping sequence evolution is the requirement that a protein fold with sufficient stability to perform its biological functions. We present...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Large capacity adjustable speed machines (ASMs) at pumped storage power station have been put into full operation and the operating characteristics of ASM have been highly evaluated from the view point of power system operation. The output power (input power) of ASM can be controlled very quickly by applying a vector control scheme to the excitation control. This quick responsive feature of ASM can make it possible to improve the stability of the neighbor sub-power system. For improvement of transient stability, the output power of ASM is reduced very quickly in order to control the acceleration of neighbor generators during and after transmission line faults. For improvement of dynamic stability, the output power of ASM is modulated in accordance with the stabilizing signals detected from the swing of generator rotor or the power flow fluctuation on the transmission line. This paper describes the ...

UK PubMed Central (United Kingdom)

Numerous studies have noted that the evolution of new enzymatic specificities is accompanied by loss of the protein's thermodynamic stability (ΔΔG), thus suggesting...Full Text Available

International Nuclear Information System (INIS)

This paper presents a practical case study on the dynamic stability of the Saudi Electricity Company (SEC) power system and its effect on increasing power transfer limit of the interconnection between Eastern Operating Area (SEC-EOA). The problem of optimal tuning of the power system stabilizer parameters was converted into optimization problem wth eigenvalue-based objective functions, which was then solved by genetic algorithms. In this regard, two eigenvalue-based objective functions were considered and the problem is solved using real-coded genetic algorithm (RCGA). The effectiveness of the suggested technique to enhance the power system dynamic stability and to extend the power transfer capability limit of the SEC-EOA and the SEC-EOA power system was verified through a comprehensive eigenvalue analysis and time-domain nonlinear simulation. The results also indicated that the proposed tuning schemes of the existing ...

UK PubMed Central (United Kingdom)

Alpha-hemoglobin-stabilizing protein (AHSP) is an erythroid-specific protein that acts as a molecular chaperone for the free α chains of hemoglobin. Evidence strongly suggests...Full Text Available

UK PubMed Central (United Kingdom)

A general procedure for stabilization of O2-labile enzymes exploiting "salting out" of oxygen from the microenvironment in the molecular layers immediately adjacent to charged surfaces of polyionic...Full Text Available

KoreaScience (Korea)

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Science.gov (United States)

... The micrometeorological community often expresses these relations in resistance law terms (Garratt and Hicks, 1973; Hicks et al., 1985) ...

Energy Technology Data Exchange (ETDEWEB)

We write a path-integral expression for the Green function of a advected scalar on a fluid flux. (author)

British Library Electronic Table of Contents (United Kingdom)

Cadmium sulfide particles have been synthesized in the aqueous medium using the amino acid histidine as a stabilizing agent. These particles demonstrate the phenomenon of size quantization effect. The fluorescence of histidine-stabilized CdS was found to be enhanced and quenched by the addition of DNA bases adenine and guanine, respectively. The fluorescence enhancement of CdS in the presence of adenine has been explained on the basis of interaction between the quantum dot stabilizer and the amino group of adenine. Quenching of CdS fluorescence by guanine occurs due to interaction of the substrate with the quantum dot surface.

Science.gov (United States)

This paper presents a systematic study on the stability of a two-dimensional vibration isolation floating raft system with a time-delayed feedback control. Based on the generalized Sturm criterion, the critical control gain for the delay-independent stability region and critical time delays for the stability switches are derived. The critical conditions can provide a theoretical guidance of chaotification design for line spectra reduction. Numerical simulations verify the correctness of the approach. Bifurcation analyses reveal that chaotification is more likely to occur in unstable region defined by these critical conditions, and the stiffness of the floating raft and mass ratio are the sensitive parameters to reduce critical control gain.

Science.gov (United States)

... in tactics, techniques, and procedures (TTP), such as ... flow across the Afghanistan-Pakistan border, specifically ... The funds from the NATO ANA Trust ...

Energy Technology Data Exchange (ETDEWEB)

This paper presents the eigenvalue control strategy which utilizes an adaptive power system stabilizer for the decentralized control of damping and frequency of electromechanical oscillations in power systems. The control procedure includes the complete identification of the decoupled subsystem model in real-time from local measurements only and the assignment of its estimated electromechanical eigenvalue by the change of stabilizer parameters. The robustness and efficiency of the proposed adaptive controller to enhance overall system stability are illustrated in several examples, including the three-machine power system model.

Science.gov (United States)

... The moisture content-dimension relationship of two laminate components, phenolic core and melamine overlay, are compared. (Author, modified). ...

Energy Technology Data Exchange (ETDEWEB)

The aim of this research is the design and implementation of a decentralized power system stabilizer (PSS) capable of performing well for a wide range of variations in system parameters and/or loading conditions. The framework of the design is based on Fuzzy Logic Control (FLC). In particular, the neuro-fuzzy control rules are derived from training three classical PSSs; each is tuned using GA so as to perform optimally at one operating point. The effectiveness and robustness of the designed stabilizer, after implementing it to the laboratory model, is investigated. The results of real-time implementation prove that the proposed PSS offers a superior performance in comparison with the conventional stabilizer. (author)

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Published in summary form only.

Science.gov (United States)

... Uninterrupted access to and use of critical infrastructure in the Arabian Gulf region are key to the successful prosecution of the Global War on Terror ...

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The stability-enchancing two-step (SETS) method has been used successfully in the Transient Reactor Analysis Code (TRAC) for several years. The method consists of a basic semi-implicit step combined with a stabilizer step that, taken together, eliminate the material Courant stability limit associated with standard semi-implicit numerical methods. This approach toward stability requires significantly fewer computational operations than a fully implicit method, but currently maintains the first-order accuracy in space and time of its semi-implicit predecessors.

UK PubMed Central (United Kingdom)

Here, we provide the first study of prolactin (PRL) and prolactin receptor (PRLR) expression during the nonseasonal murine hair cycle, which is, in contrast to sheep, comparable with the human scalp...Full Text Available

CERN Document Server

Kelvin-Helmholtz instability of short gravity waves is examined in order to explain the recent findings of the decrease in momentum transfer from hurricane winds to sea waves. A three-fluid configuration of a foam layer between the atmosphere and the ocean is suggested to provide signifficant stabilization of the system and shifting the marginal critical wavelength to the shortwave part of the spectrum. It is conjectured that such stabilization leads to the observed drag reduction. The high contrasts in three fluid densities provide a universal mechanism for stabilizing surface perturbations.

Science.gov (United States)

A method is presented for calculating the thermal stability of blast furnace coke over a wide range of sizes, based on a study of the coke behaviour pattern in the blast furnace and the change in its thermo-elastic properties during reheating. Using as an example a Novolipetsk metallurgical plant, the possibility was demonstrated of using the thermal stability index calculated by the proposed method for an unambiguous assessment of the quality of blast furnace coke.

Energy Technology Data Exchange (ETDEWEB)

At DORIS II/HASYLAB a vertical beam position control system is in regular operation. It controls the position and angle of a photon beam simultaneously, and can stabilize beam movements up to frequencies of 0.1 Hz. To suppress beam vibrations up to 50 Hz and above, a prototype beam stabilization system for these frequencies was built and tested successfully. The present beam oscillations at the HASYLAB beamlines are explained, the quality of the beam position control system and the results of the prototype test are presented.

CERN Document Server

We extend two results on Chow (semi-)stability to positive characteristics. One is on the stability of non-singular projective hypersurfaces of degree greater than 2, and the other is the criterion by Y. Lee in terms of log canonical thresholds. Some properties of log-canonicity in positive characteristics are discussed with a couple of examples, in connection with the proof of the latter one. It is also proven in appendix that the sum of Chow (semi-)stable cycles are again Chow (semi-)stable.

Energy Technology Data Exchange (ETDEWEB)

Dynamic stability improvement of a longitudinal power system using a power system stabilizer (PSS) and a static VAR compensator (SVC) is reported in this paper. An analytical approach is developed for the determination of PSS parameters. Results from time domain simulations indicate that the PSS and the SVC are very effective in damping system oscillations.

British Library Electronic Table of Contents (United Kingdom)

This paper mainly considers the asymptotic stability of interval neutral delay-differential systems, which corrects a technical error in the proof given in [Applied Math. Letters, 16(2003) 1063-1068] by a linear fractional transformation of an interconnection matrix with structured real parametric uncertainties. In addition, a new condition, in terms of the structured singular value, is provided to ensure the stability of the interval system. Finally, an example is given to demonstrate the validity of our criteria.

British Library Electronic Table of Contents (United Kingdom)

Purpose The paired-like homeodomain transcription factor 2 (PITX2) gene encodes a transcription factor controlled by the WNT/Dvl/CTNNB1 and Hedgehog/TGFB pathways in the pathogenesis of colorectal cancer (CRC). Although PITX2 is reportedly involved in various functions, including tissue development by controlling cell growth, its significance in CRC remains unclear. We report our findings regarding abnormal PITX2 expression in human CRC. Methods PITX2 expression was evaluated in 5 human CRC cell lines and 92 primary CRC samples. Cell growth was evaluated after inhibition of PITX2 expression or after exogenous introduction of PITX2. Results PITX2 expression was seen in all the five CRC cell lines. The study of tissue samples indicated that PITX2 expression was significantly higher in cancer...

Energy Technology Data Exchange (ETDEWEB)

This paper is devoted to the coordination of secondary voltage control and adaptive parameters resetting of the power system stabilizer, in order to increase stability, margins in real time operation. Secondary voltage control and the power system stabilizer are two control loops, which affect the same system parameter on different bases - that parameter is the voltage set-point of the automatic voltage regulator. It was found that their effects were complementary. In that way, through the proper coordination of actions of these two control loops open up a wide range of possibilities for ensuring the stability of bulk power systems in real time. For the establishment of this coordination, an on-line sequential algorithm is proposed which is based on adaptive resetting of the voltage set-point of the automatic voltage regulator and the PSS parameters. The efficiency of the proposed algorithm is confined ...

British Library Electronic Table of Contents (United Kingdom)

The influences of maltodextrin (MD) addition and multi-layer formation on the freeze-thaw stability of ?-lactoglobulin (?-Lg)-stabilized oil-in-water beverage emulsions (0.1 wt% corn oil, 0.006 wt% ?-Lg) were investigated. Various beverage emulsions were prepared depending on MD concentration (0?20 wt%), its dextrose equivalent (M150 or M250), and the presence or absence of additional polysaccharides (pectin, alginate, or ?-carrageenan) coatings around the emulsion droplets. All emulsions (?-Lg- and ?-Lg-polysaccharide-coated emulsions) were unstable to experimental freeze-thaw cycling in the absence of MD. In the presence of MD, all emulsions containing M250 had better stability to droplet aggregation than those with M150, regardless of MD concentrations and freeze-thawing. The optimum co...

Science.gov (United States)

A new algorithm for the design of decentralized output feedback stabilizers for large-scale electric power systems is presented in this paper. In the proposed approach, the generators which are most effective for stabilizer applications are first identified by using participation factors. Then an efficient algorithm based on decentralized pole assignment is proposed for the determination of the parameters of the power system stabilizers which, due to the difficulty associated with the communication among the geographically dispersed generating stations in a large power system, are essentially decentralized compensators using local generator outputs as their feedback signals. The proposed method is computationally efficient and can be applied to any large-scale system. The simplicity and effectiveness of the proposed method are demonstrated by an example of stabilizer design for a practical power system.

British Library Electronic Table of Contents (United Kingdom)

Abstract Purpose: To describe the pattern of expression of the cyclin-dependent kinase inhibitors (CDKIs) p16, p21 and p27, and the cell cycle in SRA 01/04 cells relative to contact inhibition. Methods: SRA 01/04 cells were grown to overconfluence under normal conditions. At various phases of the cell growth, cells were assayed by flow cytometry and Western blotting for the expression of CDKIs. Results: Expression of p16 was detected from early logarithmic growth to stationary phases, during which the number of cells in G0/G1 increased from 46 to 69%. Expression of p21 was detected only during the overgrowth phase, when 60% of the cells were in G0/G1. Expression of p27 was not observed in SRA 01/04 cells. Conclusions: p16 expression was likely mediated by G0/G1 arrest to induce contact inh...

Energy Technology Data Exchange (ETDEWEB)

This contribution provides an overview and imparts basic knowledge on pertinent technical developments in magnetic resonance imaging (MRI) of the liver: 3D sequences, respiratory triggering, parallel imaging, and 3 Tesla (3T). 3D sequences can be used as T1-weighted (T1w) sequences for analyzing dynamics of contrast enhancement or as T2w sequences for MR cholangiography. Consistent improvements in respiratory triggering make it possible to obtain good image quality on T2w scans even in patients unable to hold their breath. Parallel imaging as a universal technique to accelerate image acquisition is particularly appropriate for MRI of the liver, and it has been shown that the reduced acquisition time is not achieved at the expense of image quality. Further progress in MRI of the liver can be expected with use of the 3T systems, but hitherto irrelevant problems must still be solved. Overall the ...

CERN Document Server

We study the finite temperature electroweak transition with non-perturbative lattice Monte Carlo simulations. We find that it is of first order, at least for Higgs masses up to 80 GeV. The critical temperature of the phase transition is found to be smaller than that determined by a 2-loop renormalization group improved effective potential. The jump of the order parameter at the critical temperature is considerably larger than the perturbative value. By comparing lattice data and perturbation theory, we demonstrate that the latter, for the computation of the vacuum expectation value of the Higgs field v(T) in the broken phase at given temperature, converges quite well, provided v(T)/T>1. An upper bound on the Higgs mass necessary for electroweak baryogenesis in the light of the lattice data is briefly discussed.

International Nuclear Information System (INIS)

A four-stage scoring system for brain maturation was established with MR imaging. First, gyration and myelination were analyzed in 50 anamnestically normal children (32-240 weeks postconceptional age). Subsequently 60 patients (same age range) with birth asphyxia, seizures, or developmental delays were evaluated analogously. T1- and T2-weighted images (500/30 and 3,000/120 [repetition time msec/echo time msec]) were obtained with a 2.35-T magnet in all children. Whereas gyration abnormalities were seen in some patients, all handicapped children presented with delayed myelination. In conclusion, prospective staging of brain development (gyration and myelination) is possible and is best obtained with T2-weighted images.

Energy Technology Data Exchange (ETDEWEB)

In the first part of this contribution, the definition of reference values is given and the theoretical and practical problems in the application of this concept are discussed. In this connection, the present resources on instrumentation and the technical requirements for dose assessment are described. In the second part, some consequences are taken and proposals for further actions are made. (orig.) [German] Im ersten Teil des Aufsatzes werden die Definition von Referenzwerten in der radiologischen Diagnostik untersucht und die theoretischen und praktischen Probleme der Umsetzung des gesamten Konzepts eroertert. In diesem Zusammenhang werden auch der gegenwaertige Geraetebestand und die technischen Voraussetzungen zur Dosisermittlung beschrieben. Im zweiten Teil werden daraus Schlussfolgerungen gezogen und Vorschlaege zum weiteren Vorgehen gemacht. (orig.)

Energy Technology Data Exchange (ETDEWEB)

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired disease involving multiple hematopoietic cell lines. Characteristics of PNH are intrinsic hemolytic anemia, iron deficiency anemia and venous thrombosis. We report a case of PNH with characterostoc MR and CT findings. The signal intensity of renal cortex was lower than that of medulla on both T1-and T2-weighted MR imaging. On T2 weighted MR images, the liver showed very low signal intensity but the signal intensity of the spleen was normal. On precontrast CT the attenuation of renal cortex was higher than that of renal medulla and the attenuation of liver was higher than that of the spleen. These findings of MR imaging and CT were the result from the deposition of hemosiderin in the cells of proximal convoluted tubules and transfusional hemosiderosis of liver.

Energy Technology Data Exchange (ETDEWEB)

Purpose: The purpose of this study was to observe the process of fixation in liver specimens non-invasively by means of magnetic resonance. The fixation process of several formaldehyde-containing solutions was monitored with MRI and MRS at two different temperatures. Materials and Methods: Liver specimens were conserved in aqueous fixative solutions containing formaldehyde concentrations of 0.7, 1.8, 4 and 7.2% and at different temperatures of 5 C and 20 C. MRI was performed with T1-, T2- and PD-weighted TSE sequences, a 2D FLASH-sequence with and without magnetization transfer, and a FISP 3D-sequence on a clinical 1.5 Tesla MR whole-body unit, and MRS with {sup 1}H-spectroscopic methods (STEAM-sequence) on a 3 Tesla MR whole-body unit. Results: The diffusion of formaldehyde into the tissue was best identified on PD- and T1-weighted images as a band under the liver surface with increasing thickness, ...

British Library Electronic Table of Contents (United Kingdom)

Summary Status epilepticus or other brain-damaging insults launch a cascade of events that may lead to the development of epilepsy. MRI techniques available today, including T2- and T1-weighted imaging, functional MRI, manganese enhanced MRI (MEMRI), arterial spin labeling (ASL), diffusion tensor imaging (DTI), and phase imaging, can detect not only damage caused by status epilepticus but also plastic changes in the brain that occur in response to damage. Optimal balance between damage and recovery processes is a key for planning possible treatments, and noninvasive imaging has the potential to greatly facilitate this process and to make personalized treatment plans possible.

Science.gov (United States)

An inclusion complex between imazalil (IMZ), a selected fungicide, and cyclomaltoheptaose (beta-cyclodextrin, betaCD) was obtained using supercritical fluid carbon dioxide. The best preparation conditions were determined, and the inclusion complex was investigated by means of 1H NMR spectroscopy in aqueous solution and 13C CPMAS NMR spectroscopy in the solid state. Information on the geometry of the betaCD/IMZ complex was obtained from ROESY spectroscopy, while the dynamics of the inclusion complex in the kilohertz range was obtained from the proton spin-lattice relaxation times in the rotating frame, T(1rho) (1H). PMID:14553984

British Library Electronic Table of Contents (United Kingdom)

The aim of this study was to investigate the effects of pork/beef levels and the casings on the quality properties of semi-dried jerky. The pork/beef levels in the four test formulations were as follows: T-1 (pork: beef=100:0), T-2 (95:5), T-3 (90:10), and T-4 (80:20). After tumbling for 30min with curing solution, the cured meats were stuffed into natural sheep casings, collagen casings, or cellulose casings, and then dried. The restructured jerky with cellulose casing had the lowest water content and the highest protein content, with no significant differences between various formulations. There were no significant differences among all formulations with regard to pH and total microbial counts, and jerky with cellulose casing had the lowest value of water activity. The processing yields ...

British Library Electronic Table of Contents (United Kingdom)

Summation Copper-64 (T1/2?=?12.7 hours; ?+, 0.653?MeV [17.8 %]; ??, 0.579?MeV [38.4 %]) has decay characteristics that allow for positron emission tomography (PET) imaging and targeted radiotherapy of cancer. The well-established coordination chemistry of copper allows for its reaction with a wide variety of chelator systems that can potentially be linked to peptides and other biologically relevant small molecules, antibodies, proteins, and nanoparticles. The 12.7-hours half-life of 64Cu provides the flexibility to image both smaller molecules and larger, slower clearing proteins and nanoparticles. In a practical sense, the radionuclide or the 64Cu-radiopharmaceuticals can be easily shipped for PET imaging studies at sites remote to the production facility. Due to the versatility of 64Cu, ...

International Nuclear Information System (INIS)

Twenty-three patients with intracranial meningiomas were examined by means of magnetic resonance tomography (MRT). In 13 patients the paramagnetic contrast medium gadolinium DTPA was used. Meningiomas show only slight changes in signal intensity compared with brain in the spin-echo mode, the greatest contrast being found on photon density images (TR 1600 ms, TE 35 ms). In T1 images more than 50% of the patients showed a low signal margin between tumour and brain. Hyperostosis of the calvarium is easily recognised, but MRT is unreliable for showing tumour calcification. After intravenous injection of gadolinium DTPA, there was marked homogeneous uptake in the meningiomas. These signs are useful for the diagnosis of a meningioma by MRT. (orig.).

British Library Electronic Table of Contents (United Kingdom)

Abstract Polycystic kidney diseases (PKD) are inherited disorders characterized by fluid-filled cysts primarily in the kidneys. We previously reported differences between the expression of Cux1, p21, and p27 in the cpk and Pkd1 null mouse models of PKD. Embryonic lethality of Pkd1 null mice limits its study to early stages of kidney development. Therefore, we examined mice with a collecting duct specific deletion in the Pkd1 gene. Cux1 was ectopically expressed in the cyst lining epithelial cells of newborn, P7 and P15 Pkd1CD mice. Cux1 expression correlated with cell proliferation in early stages of cystogenesis, however, as the disease progressed, fewer cyst lining cells showed increased cell proliferation. Rather, Cux1 expression in late stage cystogenesis was associated with increased ...

Energy Technology Data Exchange (ETDEWEB)

The use of excitation system controls, specifically the Power System Stabilizer (PSS), to improve damping of power system oscillations and thus extend steady-state stability limits has been a subject of great interest in recent years. The desire to more fully utilize transmission capacity led to the installation of PSS controls on greater numbers of generating units to maintain stability margins. This paper addresses the tuning and adjustment of PSS controls in a two unit power plant. Both analytical studies and field test confirmations are presented. The practical difficulties of verifying the PSS control loop gain margin by testing are explored. A simplified procedure is outlined. The Lower Colorado River Authority (LCRA), Fayette Power Project (FPP) consists of two 683.7 MVA tandem compound steam turbine driven generators. The excitation systems are of the alternator rectifier type and the PSS control utilizes shaft ...

International Nuclear Information System (INIS)

Laser frequency stabilization giving a 500-Hz Allan deviation for a 2-ms integration time with drift reduced to 7 kHz/min over several minutes was achieved at 1536 nm in the optical communication band. A continuously regenerated spectral hole in the inhomogeneously broadened "4I_1_5_/_2(1)#->#"4I_1_3_/_2(1) optical absorption of an Er"3"+:Y_2SiO_5 crystal was used as the short-term frequency reference, while a variation on the locking technique allowed simultaneous use of the inhomogeneously broadened absorption line as a long-term reference. The reported frequency stability was achieved without vibration isolation. Spectral hole burning frequency stabilization provides ideal laser sources for high-resolution spectroscopy, real-time optical signal processing, and a range of applications requiring ultra-narrow-band light sources or coherent detection; the time scale for stability and the compatibility ...

Energy Technology Data Exchange (ETDEWEB)

This paper introduces an indirect adaptive fuzzy controller as a power system stabilizer used to damp inter-area modes of oscillation following disturbances in power systems. Compared to the IEEE standard multi-band power system stabilizer (MB-PSS), indirect adaptive fuzzy-based stabilizers are more efficient because they can cope with oscillations at different operating points. A nominal model of the power system is identified on-line using a variable structure identifier. A feedback linearization-based control law is implemented using the identified model. The gains of the controller are tuned via a particle swarm optimization routine to ensure system stability and minimum sum of the squares of the speed deviations. A bench-mark problem of a 4-machine 2-area power system is used to demonstrate the performance of the proposed controller and to show its superiority over other conventional ...

DEFF Research Database (Denmark)

We extend the pi-calculus with polyadic synchronisation, a generalisation of the communication mechanism which allows channel names to be composite. We show that this operator embeds nicely in the theory of pi-calculus, we suggest that it permits divergence-free encodings of distributed calculi, and we show that a limited form of polyadic synchronisation can be encoded weakly in pi-calculus. After showing that matching cannot be derived in pi-calculus, we compare the expressivity of polyadic synchronisation, mixed choice and matching. In particular we show that the degree of synchronisation of a language increases its expressive power by means of a separation result in the style of Palamidessi's result for mixed choice.

Energy Technology Data Exchange (ETDEWEB)

The batchwise preparation of molecular sieves for methanol conversion shows some inconsistency in catalytic stability. This is a result mainly of the change of SiO/SUB/2/Al/SUB/2O/SUB/3 in ion exchange to an H-type sieve. The dealumination during ion exchange depends upon crystal size and structural factors, which can be characterised by the cyclohexane adsorption of the raw molecular sieve. A high SiO/SUB/2/Al/SUB/2O/SUB/3 H-molecular sieve can be prepared from a molecular sieve of high adsorption capacity, this leading to a catalyst of higher stability. (4 refs.)

CERN Document Server

We introduce a family of rank functions and related notions of total transcendence for Galois types in abstract elementary classes. We focus, in particular, on abstract elementary classes satisfying the condition know as tameness (currently suspected to be a necessary condition for the development of a reasonable classification theory) where the connections between stability and total transcendence are most evident. As a byproduct, we obtain a partial upward stability transfer result for tame abstract elementary classes stable in a cardinal lambda satisfying lambda^{aleph_0}, a substantial generalization of a result of Baldwin, Kueker, and VanDieren.

Energy Technology Data Exchange (ETDEWEB)

In this paper, it is suggested that the selection method of optimal parameter of power system stabilizer (PSS) with robustness in low frequency oscillation for power system using real variable elitism genetic algorithm (RVEGA). The optimal parameters were selected in the case of power system stabilizer with one lead compensator, and two lead compensator. Also, the frequency responses characteristics of PSS, the system eigenvalues criterion and the dynamic characteristics were considered in the normal load and the heavy load, which proved usefulness of RVEGA compare with Yu's compensator design theory. (author). 20 refs., 15 figs., 8 tabs.

Energy Technology Data Exchange (ETDEWEB)

A brief description is presented of the Westinghouse Torsional Dynamic Stabilizer, which was developed primarily as a countermeasure to ''torsional interaction'' subsynchronous resonance. Two such systems were installed and commissioned at the San Juan Generating Station, Waterflow, New Mexico in July, 1980. This paper describes the maintenance procedures and operating experience to date of these two units. The only known instance of operation at the high level bias point of the Stabilizer appears to indicate that the unit helped to dampen a turbine-generator shaft oscillation transient.

Science.gov (United States)

... In addition to changes in BrdU, we also observed transient changes in p63 gene expression in the myoepithelial/stem cell layer. ...

British Library Electronic Table of Contents (United Kingdom)

Introduction The progressive growth of malignancies is accompanied by a decline in the immune response through mechanisms which are poorly understood. Apoptosis and induction of inflammation by tumor released cytokines as tumor escape mechanisms have been proposed to play an important role in colorectal carcinogenesis. Methods Expression of Tumor necrosis factor-alpha (TNF-?) was analyzed in colorectal cancer specimen and the cancer cell line HT-29 by immunohistochemistry and RT-PCR. TNF-? expression on protein and mRNA level were correlated with clinical characteristics and impact on survival. TNFR-1 was co-labelled with TNF-? and CD8+ cytotoxic T cells in immunofluorescence double staining experiments. Results: 94% (n?=?98/104) of the patients with CRC expressed TNF-?. High TNF-? express...

British Library Electronic Table of Contents (United Kingdom)

The antimicrobial peptide scygonadin (Scy) was first isolated from the gonad of Scylla serrata and its gene is predominantly expressed in the ejaculatory duct of adult males. Thus, its function was predicted to be associated with reproductive immunity, but this is still unclear and needs further investigation. In our study, the expression pattern of Scy at different developmental stages of both male and female S. paramamosain was investigated, so that the potential function of this peptide could be examined. Using real-time quantitative PCR, Scy mRNA transcripts were demonstrated obviously in the vulnerable embryos and larvae-zoea I but very weakly detected in the larvae-zoea III, megalops and juveniles. The gene expression pattern showed a decreasing trend during the early developmental s...

UK PubMed Central (United Kingdom)

BackgroundTo investigate the significance of Aurora B expression in hepatocellular carcinoma (HCC).MethodsThe Aurora B and Aurora...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

Fgf receptor 2c (Fgfr2c) was expressed in mature adipocytes of mouse white adipose tissue (WAT). To examine the role of Fgfr2c in mature adipocytes, we generated adipocyte-specific Fgfr2 knockout (Fgfr2 CKO) mice. The hypertrophy impairment of adipocytes in the mesenteric WAT but not in the subcutaneous WAT and decreased plasma free fatty acid (FFA) levels were observed in Fgfr2 CKO mice. Although the expression of genes involved in adipocyte differentiation and lipid metabolism in the mesenteric WAT was essentially unchanged, the expression of uncoupling protein 2 potentially involved in energy dissipation was significantly increased. Among potential Fgf ligands for Fgfr2c, Fgf9 was preferentially expressed in the mesenteric WAT. The present findings indicate that Fgfr2c potentially activ...

KoreaScience (Korea)

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British Library Electronic Table of Contents (United Kingdom)

High-level expression of mitotic arrest defective protein 2 (MAD2), a central component of the spindle assembly checkpoint, has been observed in a variety of human malignancies. Aim of the present study was to observe the expression of MAD2 in human non-small-cell lung cancer (NSCLC) and explore its clinicopathologic significance and evaluate MAD2 expression as a prognostic marker. MAD2 transcript was found to be overexpressed in the great majority of lung cancers by semi-quantitative RT-PCR. A total of 358 NSCLCs were analyzed immunohistochemically on tissue microarrays. High-level MAD2 expression was observed in 26.3% (94 of 358 cases), and correlated with male sex (P=0.0002), tumor progression (pT status) (P=0.0009), visceral or parietal pleural invasion (P=0.0151), non-adenocarcinoma, ...