WorldWideScience
1

Chimeric Matrix Proteins Encoded by Defective Proviruses with Large Internal Deletions in Human T-Cell Leukemia Virus Type 1-Infected Humans  

UK PubMed Central (United Kingdom)

Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia/lymphoma (ATLL), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), and other diseases....Full Text Available

2000-05-01

2

Ophthalmic abnormalities in patients with cutaneous T-cell lymphoma.  

UK PubMed Central (United Kingdom)

PURPOSE: To determine the frequency of ophthalmic abnormalities in patients with cutaneous T-cell lymphoma (mycosis fungoides and Sézary syndrome) and T-cell lymphoma involving the skin and...Full Text Available

1998-01-01

3

Granular flow considerations in the design of a cascade solid breeder reaction chamber  

International Nuclear Information System (INIS)

Both horizontally and vertically oriented rotating chambers with granular material held on the inner surface by centrifugal action are examined. Modifications to the condition for controlled quasi-static flow on an incline plane, phi/sub w/ < #alpha# < phi/sub r/, where phi/sub w/ is the wall friction angle, #alpha# is the angle of inclination of the plane, and phi/sub r/ is the drained angle of repose of the material are examined for the case of horizontal and vertical surfaces of revolution. Allowed included half angles for horizontally oriented chambers are likely to be in the range of 30"0 +- 10"0 for ceramic particles and metal surfaces. For vertical orientations the maximum half-angle of the top cone is slightly less than the wall friction angle phi/sub w/ while the lower portion can have a half angle as large as (90"0 - phi/sub w). Percolation of fines through shearing granular solids is briefly discussed and ...

1970-05-01

5

A model for estimating the hydraulic conductivity of granular material based on grain shape, grain size, and porosity  

Energy Technology Data Exchange (ETDEWEB)

Particle shape is an important parameter in numerous civil, environmental, and petroleum engineering applications. In ground-water flow, the shape of individual particles comprising the soil affects the soil`s pore size distribution and, hence, the important flow characteristics such as hydraulic conductivity and headloss. A model for delineating the relative importance of particle size, particle shape, and porosity, (and their interactions), in explaining the variability of hydraulic conductivity of a granular porous medium is developed and tested. Three types of porous media are considered in this work: spherical glass beads; granular sand; and irregularly shaped, shredded glass particles. A reliable method for quantifying the three-dimensional shape and packing of large samples of irregular particles based on their angle of repose is presented. The results of column experiments indicate that in the size range examined ...

1995-11-01

6

Possible Stratification Mechanism in Granular Mixtures  

CERN Document Server

We propose a mechanism to explain what occurs when a mixture of grains of different sizes and different shapes (i.e. different repose angles) is poured into a quasi-two-dimensional cell. Specifically, we develop a model that displays spontaneous stratification of the large and small grains in alternating layers. We find that the key requirement for stratification is a difference in the repose angles of the two pure species, a prediction confirmed by experimental findings. We also identify a kink mechanism that appears to describe essential aspects of the dynamics of stratification.

1997-01-01

7

Genetic heterogeneity in human T-cell leukemia/lymphoma virus type II.  

UK PubMed Central (United Kingdom)

DNA from the peripheral blood mononuclear cells of 17 different individuals infected with human T-cell lymphoma/leukemia virus type II (HTLV-II) was successfully amplified by the polymerase chain reaction...Full Text Available

1993-03-01

8

Epidermal keratinocytes do not activate peripheral T-cells: interleukin-10 as a possible regulator  

UK PubMed Central (United Kingdom)

The immunogenicity of allogeneic cultured human epidermal keratinocytes (cHEKs) has been studied in several models with contradictory results. We studied human T-cell activation in an in vitro...Full Text Available

2008-11-01

9

Research on deformation characteristic of AZ31Mg alloy and its constitutive equations  

Energy Technology Data Exchange (ETDEWEB)

Superplasticity of polycrystalline metallic materials is a phenomenon which shows hundreds to thousands of percents of large plastic deformation without necking in a steady state of low stress, when the uni-axial tensile loading is done in some special thermo-mechanical conditions (some limited ranges of properly high temperature and low strain rate). The main mechanism of superplastic phenomenon is the grain boundary sliding, while the main mechanism of usual plastic deformation is the trans-granular sliding. In this research, the possibility of superplastic deformation in a magnesium alloy (AZ31Mg alloy) was experimentally investigated, because generally speaking, the magnesium alloy whose atomic structure is hexagonal does not have enough formability in a form of trans-granular sliding mechanism. In this paper, the detail of experimental results are shown and discussed. Moreover, the constitutive equations of Mg alloy ...

2004-07-01

10

The mitogenic activity of human T-cell leukemia virus type I is T-cell associated and requires the CD2/LFA-3 activation pathway.  

UK PubMed Central (United Kingdom)

The presence of a high number of activated T cells in the bloodstream and spontaneous proliferation of peripheral blood mononuclear cells in vitro are striking characteristics of human T-cell leukemia...Full Text Available

1993-06-01

11

Expression of alternatively spliced human T-lymphotropic virus type I pX mRNA in infected cell lines and in primary uncultured cells from patients with adult T-cell leukemia/lymphoma and healthy carriers.  

UK PubMed Central (United Kingdom)

Although human T-cell lymphotropic virus type I (HTLV-I) is the etiologic agent of adult T-cell leukemia/lymphoma (ATL), the role of viral gene expression in the progression to and maintenance of the...Full Text Available

1992-04-01

12

Jamming in granular hopper flow.  

Energy Technology Data Exchange (ETDEWEB)

Large-scale three dimensional molecular dynamics simulations of hopper flow are presented. The flow rate of the system is controlled by the width of the aperture at the bottom. As the steady-state flow rate is reduced, the force distribution P(f) changes only slightly, while there is a large change in the impulse distribution P(i). In both cases, the distributions show an increase in small forces or impulses as the systems approach jamming, the opposite of that seen in previous Lennard-Jones simulations. This occurs dynamically as well for a hopper that transitions from a flowing to a jammed state over time. The final jammed P(f) is quite distinct from a poured packing P(f) in the same geometry. The change in P(i) is a much stronger indicator of the approach to jamming. The formation of a peak or plateau in P(f) at the average force is not a general feature of the approach to jamming.

2005-06-01

14

Development of radiological emergency preparedness technology  

Energy Technology Data Exchange (ETDEWEB)

Large-scale field tracer experiments have been conducted on Ulchin, Wolsung and Daeduk sites for the purpose of validating FADAS and of analyzing the environmental characteristics around the nuclear sites. The most influential factor in atmospheric dispersion is the meteorological condition. During the experiment, meteorological data were measured on the release point and the selected positions among sampling points. Once radioactive materials are released to the atmosphere, members of public may be exposed through the environmental media such as air, soil and foods. Therefore, to protect the public, adequate countermeasures should be taken at due time for those exposure pathways. both processes, of justification and optimization are applied to a countermeasure simultaneously for decision-making. The work scope of Biological research for the radiation protection had contained the search of biological microanalytic methods for assessing the health effect by ...

2000-04-01

15

Particulate kinematic simulations of debris avalanches: interpretation of deposits and landslide seismic signals of Mount Saint Helens, 1980 May 18:  

British Library Electronic Table of Contents (United Kingdom)

SUMMARY We construct a new class of granular landslide models in which avalanches are simulated with large numbers of independent particles moving under the influence of topographically derived gravitational and centripetal acceleration. Concurrently, the particles suffer deceleration due to basal and dynamic friction. The novel aspect of the calculation is that complex particle-to-particle interactions, fluctuating basal contacts, and unresolved topographic roughness within and below the deforming flow are mimicked by random perturbations in along-track and cross-slope acceleration. We apply the method to the 1980 May 18 Mount Saint Helens debris avalanche by constraining the initial geometry and structure of the slide mass from geological data, and the initial failure sequence from eyewi...

2006-01-01

16

Malicious Hubs: Detecting Abnormally Malicious Autonomous Systems  

Energy Technology Data Exchange (ETDEWEB)

While many attacks are distributed across botnets, investigators and network operators have recently targeted malicious networks through high profile autonomous system (AS) de-peerings and network shut-downs. In this paper, we explore whether some ASes indeed are safe havens for malicious activity. We look for ISPs and ASes that exhibit disproportionately high malicious behavior using 12 popular blacklists. We find that some ASes have over 80% of their routable IP address space blacklisted and others account for large fractions of blacklisted IPs. Overall, we conclude that examining malicious activity at the AS granularity can unearth networks with lax security or those that harbor cybercrime.

2010-03-01

17

Energy accounting for shared virtualized environments under DVFS using PMC-based power models  

British Library Electronic Table of Contents (United Kingdom)

Virtualized infrastructure providers demand new methods to increase the accuracy of the accounting models used to charge their customers. Future data centers will be composed of many-core systems that will host a large number of virtual machines (VMs) each. While resource utilization accounting can be achieved with existing system tools, energy accounting is a complex task when per-VM granularity is the goal. In this paper, we propose a methodology that brings new opportunities to energy accounting by adding an unprecedented degree of accuracy on the per-VM measurements. We present a system - which leverages CPU and memory power models based in performance monitoring counters (PMCs) - to perform energy accounting in virtualized systems. The contribution of this paper is threefold. First, w...

2012-01-01

18

Development of radiological emergency preparedness and biological dosimetry technology  

Energy Technology Data Exchange (ETDEWEB)

Large-scale field tracer experiments have been conducted on Ulchin and Wolsung nuclear sites for the purpose of validating FADAS and of analyzing the environmental characteristics around the nuclear site. The most influential factor in atmospheric dispersion is the meteorological condition. During the experiment, meteorological data were measured on the release point and the selected positions among sampling points. Once radioactive materials are released to the atmosphere, members of public may be exposed through the environmental media such as air, soil and foods. Therefore, to protect the public, adequate countermeasures should be taken at due time for those exposure pathways. Both processes of justification and optimization are applied to a countermeasure simultaneously for decision-making. The work scope of biological research for the radiation protection had contained the search of biological microanalytic methods for the assessment of health effect by ...

1999-04-01

19

Imaging immune response in vivo  

UK PubMed Central (United Kingdom)

PurposeClinical trials have commenced to evaluate the feasibility of targeting malignant gliomas with genetically engineered cytolytic T-cells (CTLs) delivered directly...Full Text Available

2008-06-15

20

Special regulatory T-cell review: A rose by any other name: from suppressor T cells to Tregs, approbation to unbridled enthusiasm  

UK PubMed Central (United Kingdom)

In the early 1970s a spate of papers by research groups around the world provided evidence for a negative regulatory role of thymus-derived lymphocytes (T cells). In 1971, Gershon and Kondo published...Full Text Available

2008-01-01

21

Reduced expression of a human V beta 6.1 T-cell receptor allele.  

UK PubMed Central (United Kingdom)

We have previously described an allelic polymorphism in the V beta 6.1 T-cell receptor gene. The V beta 6.1B allele is associated with disease in a subgroup of patients with juvenile rheumatoid arthritis....Full Text Available

1993-05-15

22

Evaluation of T-cell receptor gene rearrangements in patients with recurrent patch/plaque (T2) CTCL (mycosis fungoides).  

UK PubMed Central (United Kingdom)

Cutaneous T-cell lymphoma is typically a clonal neoplasm of epidermotropic CD4+ T-lymphocytes that includes the entity mycosis fungoides (MF). After identification of patients with recurrent MF treated...Full Text Available

1999-11-01

23

Clinical and laboratory experience of vorinostat (suberoylanilide hydroxamic acid) in the treatment of cutaneous T-cell lymphoma  

UK PubMed Central (United Kingdom)

The most common cutaneous T-cell lymphomas (CTCLs) – mycosis fungoides (MF) and Sézary Syndrome – are characterised by the presence of clonally expanded, skin-homing helper-memory...Full Text Available

2006-12-01

24

Autocrine regulation of T-cell activation by ATP release and P2X7 receptors  

UK PubMed Central (United Kingdom)

T-cell activation requires the influx of extracellular calcium, although mechanistic details regarding such activation are not fully defined. Here, we show that P2X7 receptors play a key...Full Text Available

2009-06-01

25

{beta}-decay half-lives of very neutron-rich isotopes of elements from Ti to Ni  

Energy Technology Data Exchange (ETDEWEB)

The unknown {beta}-decay half-lives of 22 isotopes far off stability (5 < T{sub Z} < 10) in the region from Ti to Ni were measured at GSI, Darmstadt. The nuclei were produced in a fragmentation reaction of 500 A.MeV {sup 86}Kr-projectile impinging on a thick Be target. The isotopes of interest were separated and identified with the fragment separator, FRS, by a combination of B{rho},Z, and ToF techniques. An additional range separation was performed by a selective implantation into granular detectors. The spatial and time correlations of the implant with the consecutively detected {beta}-particles were used to determine the unknown half-lives. For nuclei far off stability, {beta}-decay chains were measured and analyzed as well, leading to an even more reliable evaluation of the lifetimes. The large discrepancies found between the measured and the theoretical values emphasize that most recent theoretical work is not an improvement over ...

1998-03-01

26

Mechanical properties of Fe -10Ni -7Mn martensitic steel subjected to severe plastic deformation via cold rolling and wire drawing  

Energy Technology Data Exchange (ETDEWEB)

Fe-Ni-Mn martensitic steels are one of the major groups of ultra-high strength steels that have good mechanical properties and ductility in as annealed condition but they suffer from severe inter-granular embitterment after aging. In this paper, the effect of heavy shaped cold rolling and wire drawing on the mechanical properties of Fe-Ni-Mn steel was investigated. This process could provide a large strain deformation in this alloy. The total strain was {epsilon} {approx}7. Aging behavior and tensile properties of Fe-10Ni-7Mn were studied after aging at 753 K. The results showed that the ultimate tensile strength and ductility after cold rolling, wire drawing and aging increased up to 2540 MPa and 7.1 %, respectively, while the conventional steels show a premature fracture stress of 830 MPa with about zero ductility after aging.

2010-07-01

27

Mechanical properties of Fe -10Ni -7Mn martensitic steel subjected to severe plastic deformation via cold rolling and wire drawing  

International Nuclear Information System (INIS)

Fe-Ni-Mn martensitic steels are one of the major groups of ultra-high strength steels that have good mechanical properties and ductility in as annealed condition but they suffer from severe inter-granular embitterment after aging. In this paper, the effect of heavy shaped cold rolling and wire drawing on the mechanical properties of Fe-Ni-Mn steel was investigated. This process could provide a large strain deformation in this alloy. The total strain was #epsilon# #approx#7. Aging behavior and tensile properties of Fe-10Ni-7Mn were studied after aging at 753 K. The results showed that the ultimate tensile strength and ductility after cold rolling, wire drawing and aging increased up to 2540 MPa and 7.1 %, respectively, while the conventional steels show a premature fracture stress of 830 MPa with about zero ductility after aging.

2010-07-01

28

Liquefaction flowsides in Rocky Mountain coal mine waste dumps  

Energy Technology Data Exchange (ETDEWEB)

Over the past 25 years there have been a large number of long runout flowslides from Rocky Mountain coal mine waste dumps. The waste dumps are constructed as end-dumped fills with an angle of repose of 38{degrees}. Dump heights range between 100 and 400 m. The dumps are normally founded on mountain slopes that are covered with a thin veneer of granular colluvial and dense stony fill materials. Conventional stability analyses carried out for these dumps using friction angles equal to the angle of repose for the waste rock and typical values ranging from 30 to 32{degree} for the foundation materials indicate that many should be stable. The flowslides occur rapidly and display surprisingly long runouts of up to 2 km in some cases. Detailed studies of three of these events indicate that static collapse of saturated or nearly saturated sandy gravel layers within the dumps may be responsible for the initial failure and the generation of high pore ...

1998-11-01

29

#beta#-decay half-lives of very neutron-rich isotopes of elements from Ti to Ni  

International Nuclear Information System (INIS)

The unknown #beta#-decay half-lives of 22 isotopes far off stability (5 < T_Z < 10) in the region from Ti to Ni were measured at GSI, Darmstadt. The nuclei were produced in a fragmentation reaction of 500 A.MeV "8"6Kr-projectile impinging on a thick Be target. The isotopes of interest were separated and identified with the fragment separator, FRS, by a combination of B#rho#,Z, and ToF techniques. An additional range separation was performed by a selective implantation into granular detectors. The spatial and time correlations of the implant with the consecutively detected #beta#-particles were used to determine the unknown half-lives. For nuclei far off stability, #beta#-decay chains were measured and analyzed as well, leading to an even more reliable evaluation of the lifetimes. The large discrepancies found between the measured and the theoretical values emphasize that most recent theoretical work is not an improvement over calculations ...

30

Setting the standard in T-cell-depleted haploidentical transplantation and beyond  

British Library Electronic Table of Contents (United Kingdom)

Much progress has been made in the clinical, biological and technical aspects of the T-cell-depleted haploidentical hematopoietic stem cell transplantation (HSCT). Our experience demonstrates that infusing a megadose of extensively T-cell-depleted hematopoietic peripheral blood stem cells after an immuno-myeloablative conditioning regimen in acute leukemia patients ensures sustained engraftment with minimal GvHD without the need of any post-transplant immunosuppressive treatment. Since our first successful pilot study, our efforts have concentrated on developing new conditioning regimens, optimizing the graft processing and improving the post-transplant immunological recovery. The results we have so far achieved in high risk acute leukemia patients show that haploidentical transplantation ...

2011-01-01

31

Hepatosplenic T-cell lymphoma is a distinct rare entity: Diagnosis by fine-needle aspiration cytology  

British Library Electronic Table of Contents (United Kingdom)

Abstract In this brief report, we have described the fine-needle aspiration cytology (FNAC) of a hepatosplenic T-cell lymphoma (HSTCL) in a 60-year-old female patient. The patient complained of fever and heaviness of left upper abdomen. Ultrasound-guided FNAC of the spleen showed immature lymphoid cells, and a diagnosis of primary non-Hodgkin lymphoma of spleen was offered. Subsequently, the patient underwent splenectomy and wedge biopsy of liver that confirmed the cytological diagnosis. The lymphoma cells were positive for CD3 immunostain. Primary hepatosplenic T-cell lymphoma is a rare entity and may often pose diagnostic problems on FNAC. Diagn. Cytopathol. 2010. 2010 Wiley-Liss, Inc.

2011-01-01

32

Workshop on dense granular flows  

Environmental Research Database

ObjectivesThe objective of this meeting will be to interface the two ends of the particulate flow spectrum - those working to understand the fundamentals of granular flows and those attempting to control particulate flows in an industrial setting - to develop solutions to the complex problems presented by dense granular flows. We will aim~%~~%~to provide a forum for the interface between practical users of particulate technology and the developers of theories for understanding granular flow;~%~to present [continued...]DescriptionIn practical situations such as those met in industry where segregation and mixing are important, understanding particulate flows is complex due to the presence of polydispersity, anisotropy and complex grain morphology. In attempting to model such systems, many of these features are generally ignored, except perhaps through empirical parameter fitting. Developing a theory to ...

2009-01-08

33

Adhesion of Vibrio cholerae to Granular Starches  

UK PubMed Central (United Kingdom)

Cholera is a severe diarrheal disease caused by specific serogroups of Vibrio cholerae that are pathogenic to humans. Cholera can become epidemic and deadly without adequate medical...Full Text Available

2005-08-01

34

Transcriptomic analysis supports similar functional roles for the two thymuses of the tammar wallaby  

UK PubMed Central (United Kingdom)

BackgroundThe thymus plays a critical role in the development and maturation of T-cells. Humans have a single thoracic thymus and presence of a second thymus is considered an anomaly....Full Text Available

35

The influence of MHC polymorphism on the selection of T-cell determinants of FMDV in cattle.  

UK PubMed Central (United Kingdom)

There is a quest for the development of a new generation of vaccines consisting of well-defined subunit antigens. For a number of practical reasons it is attractive to develop vaccines on the basis...Full Text Available

1995-01-01

36

The Structure of the Dust Mite Allergen Der p 7 Reveals Similarities to Innate Immune Proteins  

UK PubMed Central (United Kingdom)

BackgroundSensitization to house dust mite allergens is strongly correlated with asthma. Der p 7 elicits strong IgE antibody and T-cell responses in mite allergic...Full Text Available

2010-04-01

37

Ia-antigen-T-cell interactions for a thymus-independent antigen composed of D amino acids.  

UK PubMed Central (United Kingdom)

Synthetic polypeptide antigens of L amino acids, although bearing repeating sequences, are thymus-dependent (L-TD), whereas the same polymers composed of D amino acids are thymus-independent (D-TI),...Full Text Available

1993-02-01

38

Evaluation of Two Homologous Proline-Rich Proteins of Coccidioides posadasii as Candidate Vaccines against Coccidioidomycosis?  

UK PubMed Central (United Kingdom)

Evaluation of the protective efficacy of recombinant T-cell-reactive proteins of Coccidioides posadasii in a murine model of coccidioidomycosis has led to the discovery of potential...Full Text Available

2007-12-01

39

Early inflammatory markers in elicitation of allergic contact dermatitis  

UK PubMed Central (United Kingdom)

BackgroundAllergic Contact Dermatitis (ACD) is regarded as a T-cell-mediated delayed-type hypersensitivity reaction. We studied the kinetics of the expression of CS-1 fibronectin,...Full Text Available

40

Breakdown of the Blood-Brain Barrier during Tick-Borne Encephalitis in Mice Is Not Dependent on CD8+ T-Cells  

UK PubMed Central (United Kingdom)

Tick-borne encephalitis (TBE) virus causes severe encephalitis with serious sequelae in humans. The disease is characterized by fever and debilitating encephalitis that can progress to chronic illness...Full Text Available

41

Spiral modes in the diffusion of a single granular particle on a vibrating surface  

International Nuclear Information System (INIS)

We consider a particle that is subject to a constant force and scatters inelastically on a vibrating periodically corrugated floor. At small friction and for small scatterers the dynamics is dominated by resonances forming spiral structures in phase space. These spiral modes lead to pronounced maxima and minima in the diffusion coefficient as a function of the vibration frequency, as is shown in computer simulations. Our theoretical predictions may be verified experimentally by studying transport of single granular particles on vibratory conveyors.

2004-11-29

42

Particle size effect on strength, failure, and shock behavior in polytetrafluoroethylene-Al-W granular composite materials  

Science.gov (United States)

The variation of metallic particle size and sample porosity significantly alters the dynamic mechanical properties of high density granular composite materials processed using a cold isostatically pressed mixture of polytetrafluoroethylene (PTFE), aluminum (Al), and tungsten (W) powders. Quasistatic and dynamic experiments are performed with identical constituent mass fractions with variations in the size of the W particles and pressing conditions. The relatively weak polymer matrix allows the strength and fracture modes of this material to be governed by the granular type behavior of agglomerated metal particles. A higher ultimate compressive strength was observed in relatively high porosity samples with small W particles compared to those with coarse W particles in all experiments. Mesoscale granular force chains of the metallic particles explain this unusual phenomenon as observed in hydrocode simulations of a ...

2008-11-01

43

Discovery of low-affinity preproinsulin epitopes and detection of autoreactive CD8 T-cells using combinatorial MHC multimers.  

Science.gov (United States)

Autoreactive cytotoxic CD8 T-cells (CTLs) play a key pathogenic role in the destruction of insulin-producing beta-cells resulting in type 1 diabetes. However, knowledge regarding their targets is limited, restricting the ability to monitor the course of the disease and immune interventions. In a multi-step discovery process to identify novel CTL epitopes in human preproinsulin (PPI), PPI was digested with purified human proteasomes, and resulting COOH-fragments aligned with algorithm-predicted HLA-binding peptides to yield nine potential HLA-A1, -A2, -A3 or -B7-restricted candidates. An UV-exchange method allowed the generation of a repertoire of multimers including low-affinity HLA-binding peptides. These were labeled with quantum dot-fluorochromes and encoded in a combinatorial fashion, allowing parallel and sensitive detection of specific, low-avidity T-cells. Significantly increased frequencies of T-cells against four ...

2011-05-31

44

Numerical Algorithms for Two-Dimensional Dry Granular Flow with Deformable Elastic Grain  

Energy Technology Data Exchange (ETDEWEB)

The authors consider the dynamics of interacting elastic disks in the plane. This is an experimentally realizable two-dimensional model of dry granular flow where the stresses can be visualized using the photoelastic effect. As the elastic disks move in a vacuum, they interact through collisions with each other and with the surrounding geometry. Because of the finite propagation speed of deformations inside each grain it can be difficult to capture computationally even simple experiments involving just a few interacting grains. The goal of this project is to improve our ability to simulate dense granular flow in complex geometry. They begin this process by reviewing some past work, how they can improve upon previous work. the focus of this project is on capturing the elastic dynamics of each grain in an approximate, computationally tractable, model that can be coupled to a molecular dynamics scheme.

2005-08-11

45

Modeling and optimization of a propeller-type tribocharger for granular materials  

British Library Electronic Table of Contents (United Kingdom)

Electrostatic separation has already proved to be an effective means for the recycling of granular plastics from industrial wastes. The aim of the present work was to optimize the operation of a novel device that could ensure effective triboelectric charging of such materials prior to their selective sorting in a high-intensity electric field. The experiments were performed on two sorts of mm-size granular materials Acrylonitrile Butadiene Styrene and High Impact Polystyrene, originating from the processing of waste electric and electronic equipment. The samples were introduced in a Polyvinyl Chloride cylinder, where a co-axial propeller entrained the plastic granules into a helical motion that favored their triboelectric charging by combining the mechanical and aerodynamical effects. The ...

2011-01-01

46

Strategies to optimize the outcome of children given T-cell depleted HLA-haploidentical hematopoietic stem cell transplantation  

British Library Electronic Table of Contents (United Kingdom)

The most advanced frontier of allogeneic hematopoietic stem cell transplantation (allo-HSCT) is represented by the use of an HLA-partially matched relative as donor. In this type of transplantation, donor-derived natural killer (NK) cells, which are alloreactive towardtoward recipient cells, significantly contribute to the eradication of leukemia blasts. Alloreactive NK cells may also kill host dendritic cells and T lymphocytes, thus preventing graft-versus-host disease and graft rejection, respectively. Sophisticated strategies of adoptive infusion of T-cell lines/clones specific for the most life-threatening pathogens (namely cytomegalovirus, Epstein-Barr virus, Aspergillus and Adenovirus) have been envisaged, and successfully tested in a few pilot trials, to protect the recipient in the...

2011-01-01

47

Identification of a functional nuclear export signal in the green fluorescent protein asFP499  

International Nuclear Information System (INIS)

The green fluorescent protein (GFP) asFP499 from Anemonia sulcata is a distant homologue of the GFP from Aequorea victoria. We cloned the asFP499 gene into a mammalian expression vector and showed that this protein was expressed in the human lymphoblast cell line Ramos RA1 and in the embryonic kidney 293T cell line (HEK 293T). In HEK 293T cells, asFP499 was localized mainly in the cytoplasm, suggesting that the protein was excluded from the nucleus. We identified _1_9_4LRMEKLNI_2_0_1 as a candidate nuclear export signal in asFP499 and mutated the isoleucine at position 201 to an alanine. Unlike the wildtype form, the mutant protein was distributed throughout the cytoplasm and nucleus. This is First report of a GFP that contains a functional NES.

2006-04-21

48

Herpesvirus saimiri infection of rhesus macaques: A model for acute rhadinovirus-induced t-cell transformation and oncogenesis  

British Library Electronic Table of Contents (United Kingdom)

Abstract Herpesvirus saimiri (HVS) causes acute lymphoma and leukemia upon experimental infection of various monkey species. HVS strain C488 is also capable of transforming human T-lymphocytes to stable growth in culture. The most susceptible species for oncogenesis are New World primates, in particular the cottontop tamarin (Saguinus oedipus). However, Old World monkeys such as macaques are the most used animal model for the close-to-human situation. The limited data on HVS infection in Old World monkeys prompted us to investigate susceptibility to infection and disease induction by HVS in macaques. After having established that rhesus macaques can be infected productively, and that rhesus T-cells can be transformed in vivo by HVS, we observed induction of lymphoma in all inoculated anima...

2011-01-01

49

Toxicity of N-substituted aromatics to acetoclastic methanogenic activity in granular sludge.  

UK PubMed Central (United Kingdom)

N-substituted aromatics are important priority pollutants entering the environment primarily through anthropogenic activities associated with the industrial production of dyes, explosives, pesticides,...Full Text Available

1995-11-01

50

High-Rate Anaerobic Treatment of Wastewater at Low Temperatures  

UK PubMed Central (United Kingdom)

Anaerobic treatment of a volatile fatty acid (VFA) mixture was investigated under psychrophilic (3 to 8°C) conditions in two laboratory-scale expanded granular sludge bed reactor stages in series....Full Text Available

1999-04-01

51

Experimental autoimmune encephalomyelitis mobilizes neural progenitors from the subventricular zone to undergo oligodendrogenesis in adult mice  

UK PubMed Central (United Kingdom)

The destiny of the mitotically active cells of the subventricular zone (SVZ) in adult rodents is to migrate to the olfactory bulb, where they contribute to the replacement of granular and periglomerular...Full Text Available

2002-10-01

52

Enrichment of Thermophilic Propionate-Oxidizing Bacteria in Syntrophy with Methanobacterium thermoautotrophicum or Methanobacterium thermoformicicum  

UK PubMed Central (United Kingdom)

Thermophilic propionate-oxidizing, proton-reducing bacteria were enriched from the granular methanogenic sludge of a bench-scale upflow anaerobic sludge bed reactor operated at 55°C with a mixture...Full Text Available

1992-01-01

53

Testing of CoTreat Inorganic Ion Exchange Media for the Removal of 60Co from Thorp Pond Water  

Energy Technology Data Exchange (ETDEWEB)

CoTreat, a new inorganic ion exchange media, has been studied in the laboratory to support its application as a pre- coat to existing Funda filters in THORP feed pond plant (Sellafield, UK). This is a novel way of application of CoTreat, which is usually utilized in fixed-bed ion exchange columns in a granular form. The results present the effect of operating conditions (CoTreat dose, pond water chemistry) on CoTreat performance for the removal of Co-57 tracer from simulated pond water. Major findings include the strong dependence of Co-57 decontamination factor (DF) on feed activity. At the 200 Bq/L feed level, the observed DF was 10-20 but rose to 1000 and above when the feed level was increased to 20000 Bq/L. Calcium present in the feed was found to decrease the DF at concentrations higher than 1 ppm. The laboratory studies showed significantly higher DF's than what has been observed in large-scale THORP tests. This discrepancy is ...

2003-02-25

54

High volume fly ash RCC for dams - I : mixture optimization and mechanical properties  

Energy Technology Data Exchange (ETDEWEB)

Roller compacted concretes (RCC) were developed for the Norwegian Skjerka hydropower project. RCCs were developed to have a high-volume fly ash content to address environmental issues, including the reduction of carbon dioxide emissions associated with dam construction. They also makes good use of waste product and conserve natural resources. This study examined a series of mixtures to determine the appropriateness of using RCC as a competing alternative to the traditional rock fill dam proposed for the Skjerka hydropower project. The main advantage of RCC is speed, allowing a relatively large dam to be constructed in just one summer season, saving financial costs and providing early return on the investment. In addition, fly ash can be used in the structure, using clean and renewable energy. Several procedures to proportion RCC mixtures were proposed, including the optimal paste volume method which is based on the assumption that an optimal RCC should have just ...

2001-07-01

55

Durability of cement-based materials: modeling of the influence of physical and chemical equilibria on the microstructure and the residual mechanical properties; Durabilite des materiaux cimentaires: modelisation de l'influence des equilibres physico-chimiques sur la microstructure et les proprietes mecaniques residuelles  

Energy Technology Data Exchange (ETDEWEB)

A large part of mechanical and durability characteristics of cement-based materials comes from the performances of the hydrated cement, cohesive matrix surrounding the granular skeleton. Experimental studies, in situ or in laboratory, associated to models, have notably enhanced knowledge on the cement material and led to adapted formulations to specific applications or particularly aggressive environments. Nevertheless, these models, developed for precise cases, do not permit to specifically conclude for other experimental conclusions. To extend its applicability domain, we propose a new evolutive approach, based on reactive transport expressed at the microstructure scale of the cement. In a general point of view, the evolution of the solid compounds of the cement matrix, by dissolutions or precipitations, during chemical aggressions can be related to the pore solution evolution, and this one relied to the ionic exchanges with the external ...

2004-09-15

56

Emission and excitation spectra of feldspar inclusions within quartz  

Energy Technology Data Exchange (ETDEWEB)

Emission spectra obtained for three irradiated granular quartz samples under 1.43 eV excitation exhibited the 2.2 and 3.1 eV emission bands characteristic of feldspars. Excitation spectra of these same samples and several others show the 1.44 eV resonance typical of feldspars. This provides convincing evidence that the 2.2 and 3.1 eV infrared stimulated luminescence observed in these granular quartz samples arises from feldspar inclusions.

2004-02-01

57

Electromagnetic pump  

Energy Technology Data Exchange (ETDEWEB)

In an electromagnetic pump of the present invention for use in circulation of coolants in an LMFBR type reactor, the outer circumference of coil conductors is covered by an insulator retaining cover, and powdery or granular insulator is filled between the coil conductors and the insulator retaining cover. Upon reaching high temperature, elongation of the coil conductors by heat expansion is absorbed by movement of the particles of the powdery insulator thereby preventing excess stresses from exerting on the coil insulator constituted with the insulator retaining cover and the powdery or granular insulator and preventing generation of crackings on the coil insulator. Thus, plant stability is improved. (N.H.).

1994-05-13

58

Viral suppression of multiple escape mutants by de novo CD8+ T cell responses in a human immunodeficiency virus-1 Infected elite suppressor  

UK PubMed Central (United Kingdom)

Elite suppressors or controllers (ES) are HIV-1 infected patients who maintain undetectable viral loads without treatment. While HLA-B*57-positive ES are usually infected with virus that is unmutated...Full Text Available

59

Vaccination response to tetanus toxoid and 23-valent pneumococcal vaccines following administration of a single dose of abatacept: a randomized, open-label, parallel group study in healthy subjects  

UK PubMed Central (United Kingdom)

The effect of abatacept, a selective T-cell co-stimulation modulator, on vaccination has not been previously investigated. In this open-label, single-dose, randomized, parallel-group, controlled study,...Full Text Available

2007-01-01

60

SIV antigen immunization induces transient antigen-specific T cell responses and selectively activates viral replication in draining lymph nodes in retroviral suppressed rhesus macaques  

UK PubMed Central (United Kingdom)

BackgroundHIV infection causes a qualitative and quantitative loss of CD4+ T cell immunity. The institution of anti-retroviral therapy (ART) restores CD4+ T...Full Text Available

61

Mapping of TH1 helper T-cell epitopes on major secreted mycobacterial antigen 85A in mice infected with live Mycobacterium bovis BCG.  

UK PubMed Central (United Kingdom)

TH1 cytokine secretion was examined in response to synthetic peptides of the 85A component of the major secreted, fibronectin-binding antigen 85 complex from Mycobacterium tuberculosis in seven different...Full Text Available

1994-02-01

62

Long-Term Specific Immune Responses Induced in Humans by a Human Immunodeficiency Virus Type 1 Lipopeptide Vaccine: Characterization of CD8+-T-Cell Epitopes Recognized  

UK PubMed Central (United Kingdom)

We studied the effect of booster injections and the long-term immune response after injections of an anti-human immunodeficiency virus type 1 (HIV-1) lipopeptide vaccine. This vaccine was injected alone...Full Text Available

2003-10-01

63

Helper T-Cell Epitopes Encoded by the Babesia bigemina rap-1 Gene Family in the Constant and Variant Domains Are Conserved among Parasite Strains  

UK PubMed Central (United Kingdom)

Among important candidates for babesial vaccines are apical complex proteins, including rhoptry-associated protein 1 (RAP-1) from Babesia bovis and B. bigemina, which...Full Text Available

1998-04-01

64

Extracorporeal Photochemotherapy as a Challenging Treatment for Cutaneous T-Cell Lymphoma, Acute and Chronic Graft-versus-Host Disease, Organ Rejection and T-Lymphocyte-Mediated Autoimmune Diseases  

UK PubMed Central (United Kingdom)

Summary20 years ago, in 1987, Edelson and co-workers published their first report on the effectiveness of a new procedure, called extracorporeal photochemotherapy (ECP), in patients...Full Text Available

2008-01-01

65

Differentiation associated regulation of microRNA expression in vivo in human CD8+ T cell subsets  

UK PubMed Central (United Kingdom)

BackgroundThe differentiation of CD8+ T lymphocytes following priming of naïve cells is central in the establishment of the adaptive immune response. Yet, the...Full Text Available

66

Differential Specificity and Immunogenicity of Adenovirus Type 5 Neutralizing Antibodies Elicited by Natural Infection or Immunization?  

UK PubMed Central (United Kingdom)

A recent clinical trial of a T-cell-based AIDS vaccine delivered with recombinant adenovirus type 5 (rAd5) vectors showed no efficacy in lowering viral load and was associated with increased risk of...Full Text Available

2010-01-01

67

CD5 Is Dissociated from the B-Cell Receptor in B Cells from Bovine Leukemia Virus-Infected, Persistently Lymphocytotic Cattle: Consequences to B-Cell Receptor-Mediated Apoptosis  

UK PubMed Central (United Kingdom)

Bovine leukemia virus (BLV), a retrovirus related to human T-cell leukemia virus types 1 and 2, can induce persistent nonneoplastic expansion of the CD5+ B-cell population, termed...Full Text Available

2001-02-01

68

Sex and seasonal differences in the rate of cell proliferation in the dentate gyrus of adult wild meadow voles.  

Science.gov (United States)

In order to study the neurobiological basis of seasonal changes in hippocampal structure and function, the rate of cell proliferation was examined in male and female wild meadow voles captured during different seasons. We found that the number of [3H]thymidine-labeled cells varied across the seasons and across sex in the meadow vole. Non-breeding female meadow voles had a higher rate of cell proliferation and cell death than males captured during either season or breeding females. These seasonal changes in the female meadow vole were associated with both fluctuating levels of adrenal steroids and gonadal steroids. Estradiol level was highly correlated with both the number of [3H]thymidine-labeled cells and the number of pyknotic cells in female meadow voles, with high levels of estradiol being associated with low levels of cell proliferation and cell death. Corticosterone level was associated with the number of [3H]thymidine-labeled cells in the hilus of female meadow voles. This ...

1999-03-01

69

Field Studies of the Electrical Properties of Permeable Reactive Barriers for Monitoring Barrier Aging  

Science.gov (United States)

Permeable reactive barriers (PRB) are a promising technology for the remediation of groundwater containing a range of organic and inorganic contaminants. Although there are number of different types of reactive barriers, some of the most important are constructed from granular zero valent iron (ZVI). One challenge in the large- scale, long-term implementation of PRBs is to monitor the change in barrier properties over time. For example, mineral precipitates can reduce the effectiveness of the barrier by either insulating the reaction surfaces of the ZVI particles and/or by filling the pore space in the barrier and thus reducing its hydraulic permeability. Previous research has shown that resistivity and induced polarization (IP) measurements are sensitive to corrosion and precipitation due to redox reactions between ions in solution and the ZVI mineral surface. New field studies, supported by additional laboratory studies appear to confirm ...

2006-12-01

70

Enhancement of N-nitrosamine formation on granular-activated carbon from N-methylaniline and nitrite  

Energy Technology Data Exchange (ETDEWEB)

Sterile aqueous N-methylaniline solutions were allowed to equilibrate at various nitrite, F-400 granular-activated carbon, and pH levels for 1 week. The aqueous and activated carbon phases were extracted and analyzed for nitrosamines relative to an added internal standard. Selected ion monitoring GC/MS, utilizing continuous monitoring of the NO/sup +/ ion (m/z 29.9980) characteristic of nitrosamines, at medium resolution (R = 2500-3000) was applied to quantitatively measure nitrosamines at picograms per microliter concentrations. This method selected for nitrosamine products only and eliminated interferences from non-nitrosamine reaction products. Results indicate that the pressure of granular-activated carbon significantly enhanced the formation of nitrosamine from N-methyl-aniline (F = 145, P< 0.0001). The amount of N-nitrosomethylaniline formed in the presence of activated carbon was 75 times more than that formed in the absence of ...

1986-10-01

71

Electricity generation and microbial community changes in microbial fuel cells packed with different anodic materials.  

Science.gov (United States)

Four materials, carbon felt cube (CFC), granular graphite (GG), granular activated carbon (GAC) and granular semicoke (GS) were tested as packed anodic materials to seek a potentially practical material for microbial fuel cells (MFCs). The microbial community and its correlation with the electricity generation performance of MFCs were explored. The maximum power density was found in GAC, followed by CFC, GG and GS. In GAC and CFC packed MFCs, Geobacter was the dominating genus, while Azospira was the most populous group in GG. Results further indicated that GAC was the most favorable for Geobacter adherence and growth, and the maximum power densities had positive correlation with the total biomass and the relative abundance of Geobacter, but without apparent correlation with the microbial diversity. Due to the low content of Geobacter in GS, power generated in this system may be attributed to other microorganisms such as ...

2011-09-20

72

Long Range Correlation in Granular Shear Flow II: Theoretical Implications  

CERN Document Server

Numerical simulations are used to test the kinetic theory constitutive relations of inertial granular shear flow. These predictions are shown to be accurate in the dilute regime, where only binary collisions are relevant, but underestimate the measured value in the dense regime, where force networks of size $\\xi$ are present. The discrepancy in the dense regime is due to non-collisional forces that we measure directly in our simulations and arise from elastic deformations of the force networks. We model the non-collisional stress by summing over all paths that elastic waves travel through force networks. This results in an analytical theory that successfully predicts the stress tensor over the entire inertial regime without any adjustable parameters.

2006-01-01

73

Influence of shape on ordering of granular systems in two dimensions  

Energy Technology Data Exchange (ETDEWEB)

We investigate ordering properties of two-dimensional granular materials using several shapes created by welding ball bearings together. Ordered domains form much more easily in two than in three dimensions, even when configurations lack long-range order. The onset of ordered domains occurs near a packing density of 0.8, a phenomenon observed previously for disks. One of our shapes, the trapezoid, has packings that remain disordered and near the transition density even after annealing by shaking. Although random packings are unstable for disks and many other shapes in two dimensions, trapezoid packings provide an approach to studying two-dimensional randomness. We also find that the rotational symmetry of a shape is an excellent predictor of how easily it orders, and a potential guide to identifying two-dimensional shapes that remain random after annealing.

2001-06-01

74

Glass-heat-pipe evacuated-tube solar collector  

Science.gov (United States)

A glass heat pipe is adapted for use as a solar energy absorber in an evacuated tube solar collector and for transferring the absorbed solar energy to a working fluid medium or heat sink for storage or practical use. A capillary wick is formed of granular glass particles fused together by heat on the inside surface of the heat pipe with a water glass binder solution to enhance capillary drive distribution of the thermal transfer fluid in the heat pipe throughout the entire inside surface of the evaporator portion of the heat pipe. Selective coatings are used on the heat pipe surface to maximize solar absorption and minimize energy radiation, and the glass wick can alternatively be fabricated with granular particles of black glass or obsidian.

1981-08-06

75

Development of a waterjet system for direct delivery of granular iron and activated carbon to remediate contaminated aqueous sediments  

British Library Electronic Table of Contents (United Kingdom)

Abstract While the techniques and technologies associated with contaminated sediment remediation are relatively mature, there are several issues associated with these practices that make them unattractive. The inability of currently used mechanical mixing implements to place amendments in aqueous environments and their intrusive behavior toward benthic communities are just two examples of a necessity for an improved delivery method. Waterjets may be a viable option for placement of particulate remediation amendments, such as activated carbon and granular iron, at depth. A custom waterjet nozzle and injection system has been fabricated by the authors to examine this delivery concept. The developed injection system's performance was tested by characterizing the waterjet-delivered amendment (...

2011-01-01

76

Continuum theory of axial segregation in a long rotating drum  

Energy Technology Data Exchange (ETDEWEB)

We develop a continuum description for the axial segregation of granular materials in a long rotating drum based on the dynamics of the thin near-surface granular flow coupled to bulk flow. The equations of motion are reduced to the one-dimensional system for two local variables only, the concentration difference and the dynamic angle of repose, or the average slope of the free surface. The parameters of the system are established from comparison with experimental data. The resulting system describes both initial transient traveling wave dynamics and the formation of quasi-stationary bands of segregated materials. A long-term evolution proceeds through slow logarithmic coarsening of the band structure which is analogous to the spinoidal decomposition described by the Cahn-Hilliard equation. {copyright} {ital 1999} {ital The American Physical Society}

1999-08-01

77

Continuum theory of axial segregation in a long rotating drum  

International Nuclear Information System (INIS)

We develop a continuum description for the axial segregation of granular materials in a long rotating drum based on the dynamics of the thin near-surface granular flow coupled to bulk flow. The equations of motion are reduced to the one-dimensional system for two local variables only, the concentration difference and the dynamic angle of repose, or the average slope of the free surface. The parameters of the system are established from comparison with experimental data. The resulting system describes both initial transient traveling wave dynamics and the formation of quasi-stationary bands of segregated materials. A long-term evolution proceeds through slow logarithmic coarsening of the band structure which is analogous to the spinoidal decomposition described by the Cahn-Hilliard equation. copyright 1999 The American Physical Society

1999-08-01

78

Total skin electron beam and total nodal irradiation for treatment of patients with cutaneous T-cell lymphoma  

Energy Technology Data Exchange (ETDEWEB)

Sixteen patients with advanced cutaneous T-cell lymphoma (CTCL) with or without lymph node involvement, but without evidence of extranodal manifestations, were treated with a combination of total skin electron beam therapy (TSEB) and total nodal irradiation (TNI). Fourteen (87%) patients achieved a complete response (CR) lasting from 1 to 84+ months (median, 8+ months) from the completion of treatment. The best results occurred in 6 patients with pretumorous intracutaneous CTCL (Stages IB and IIA) where the CR has lasted in all patients from 8 to 84+ months (median about 27+ months). Radiotherapy was well tolerated with the major toxicity being bone marrow suppression. The authors conclude that combined TSEB and TNI is a relatively safe and effective treatment for patients with CTCL prior to the development of lymph node involvement. Long-term follow-up is needed to assess the curative potential of this treatment.

1985-06-01

79

Human T-cell lymphotropic virus type III infection of the central nervous system: a preliminary in situ analysis  

Energy Technology Data Exchange (ETDEWEB)

Patients with acquired immunodeficiency syndrome (AIDS) are subject to a spectrum of central nervous system (CNS) disorders. Recent evidence implicates the human T-cell lymphotropic virus type III (HTLV-III) in the pathogenesis of some of these illnesses, although the cells infected by the virus have yet to be identified. Using in situ hybridization, the authors examined brain tissue from two patients with AIDS encephalopathy for the presence of HTLV-III RNA. In both cases, viral RNA was detected and concentrated in, though not limited to, the white matter. The CNS cells most frequently infected included macrophages, pleomorphic microglia, and multinucleated giant cells. Less frequently, cells morphologically consistent with astrocytes, oligodendroglia, and rarely neurons were also infected. The findings strengthen the association of HTLV-III with the pathogenesis of AIDS encephalopathy. In situ hybridization can be applied to routinely prepared biopsy tissue in ...

1986-11-07

80

Dual-field rotational (DFR) technique for total-skin electron-beam therapy (TSEBT)  

Energy Technology Data Exchange (ETDEWEB)

Comparison of dosimetry measured in a noncylindrical Rando-Alderson phantom by two-field, four-field, and six-field total-skin electron-beam therapy (TSEBT) techniques with our dual-field rotational (DFR) technique reveals a superior dosimetry for the latter. Our technique of dual-field rotational DFR-TSEBT is described in detail, and its advantages and indications for the primary management of cutaneous T-cell lymphoma (CTCL) and Kaposi's sarcoma (KS) are discussed.

1987-08-01

81

Expression of bacterial luciferase in eukaryotic cells  

International Nuclear Information System (INIS)

Expression of Bacterial luciferase enzyme (lux) in mammalian cells would be a powerful bioreporter protein system for in vivo imaging because eukaryotic luciferases need expensive substrates. However, only a few efforts have been made to express bacterial luciferase enzyme in mammalian cells. As the result of this, we attempted to construct bicistronic vector including two bacterial luciferase genes (LuxA and LuxB) for assessing the potential to be visualized in vitro or in vivo by optical imaging system after transfection to mammalian cells. We designed and synthesized luxA and luxB genes from Photorhabdus Luminescens. To co-express both luxA and luxB genes from a single promoter, we cloned as a bicistronic transcript fused with an internal ribosomal entry site (IRES). This bicistronic transcript was transfected by Superfect to HEK 293T cell line. We also transfected lux A and lux B vector to HEK 293T ...

2005-11-18

82

Studying the internal structure of granular magnetic nanocomposites by ferromagnetic resonance  

British Library Electronic Table of Contents (United Kingdom)

A method for estimating the form of magnetic nanoparticles in composite film structures based on the observation of ferromagnetic resonance phenomenon is offered. Within the model of the effective medium, an explanation is given for experimentally observed concentration and temperature dependences of resonant fields for composite nanosystem (Co45Fe45Z10) f +(Al2O3)100?f .

2010-01-01

83

ONR-NRL Superconducting Materials Symposium: A forecast  

Science.gov (United States)

Partial Contents: Ternary Compounds; Granular Superconductors; Superconductivity in (SN)x and its Halogen Derivative (SNBr0.4)x; Studies of cuCl at Elevated Pressures; Superconducting Properties of Hydride Systems; Thin Film Superconducting Materials Research; Synthesis of Superconducting Nb3Si using High Pressures; Synthesis of Unstable A-15 Compounds by Epitaxial Recrystallization of Ion Implanted Layers; and Sputtering of Nb3Si.

1979-01-01

84

In Situ Detection, Isolation, and Physiological Properties of a Thin Filamentous Microorganism Abundant in Methanogenic Granular Sludges: a Novel Isolate Affiliated with a Clone Cluster, the Green Non-Sulfur Bacteria, Subdivision I  

UK PubMed Central (United Kingdom)

We previously showed that very thin filamentous bacteria affiliated with the division green non-sulfur bacteria were abundant in the outermost layer of thermophilic methanogenic sludge granules fed...Full Text Available

2001-12-01

85

Dynamics of Axial Separation in Long Rotating Drums  

Energy Technology Data Exchange (ETDEWEB)

We propose a continuum description for the axial separation of granular materials in a long rotating drum. The model, operating with two local variables, concentration difference and the dynamic angle of repose, describes both initial transient traveling wave dynamics and long-term segregation of the binary mixture. Segregation proceeds through ultraslow logarithmic coarsening. {copyright} {ital 1999} {ital The American Physical Society}

1999-06-01

86

Active recycling of plastics  

Energy Technology Data Exchange (ETDEWEB)

The numerous types of plastic materials and their varying structures of use call for different recycling techniques. This situation is illustrated by the survey of the most important recycling methods. Depending on origin and type of plastic waste, not only different recycling methods have to be adopted, but the resulting recycling materials are also used for different purposes. Disintegration of thermoplastic particles and waste into granular matter and grains which can be directly reused is particularly important.

1987-01-01

87

Zebrafish embryo extracts promote sphere-forming abilities of human melanoma cell line  

British Library Electronic Table of Contents (United Kingdom)

Sphere-forming abilities in culture condition are considered a hallmark of cancer stem-like cells, which represents tumor cell invasiveness and stem-like characteristics. We aimed to show that the sphere-forming subpopulation of human malignant melanoma cell line WM-266-4 acts differently to zebrafish embryo extracts compared with their bulk counterpart. Spheres were maintained in neural stem cell culture conditions. The embryos of zebrafish at specific developmental stages were collected and the extracts were purified under 100 kDa. Spheres were treated with embyo extracts and proliferation assay and immunocytochemistry were conducted. Spheroid cells expressed nestin and epidermal growth factor receptor (EGFR) but not melanoma antigen recognized by T-cells (MART)1, indicating their stem-l...

2009-01-01

88

Treatment of hematological malignancies with nonmyeloablative, HLA-haploidentical bone marrow transplantation and high dose, post-transplantation cyclophosphamide  

British Library Electronic Table of Contents (United Kingdom)

Hematopoietic stem cell transplantation provides the only potential curative option in many patients with hematological malignancies. Finding a suitably matched donor in a timely manner is often difficult. However, most patients have a partially HLA-mismatched (HLA-haploidentical) first-degree relative readily available. Historically, HLA-haploidentical bone marrow transplantation (BMT) has been considered extremely high risk due to high rates of life-threatening graft-versus-host disease (GVHD) and non-relapse mortality (NRM). Modifications of the stem cell graft, such as T-cell depletion, have resulted in poor rates of engraftment. We have recently completed a phase II clinical trial of nonmyeloablative HLA-haploidentical hematopoietic BMT followed by post-transplantation high-cyclophosp...

2011-01-01

89

Role of regulatory T cell populations in controlling graft vs host disease  

British Library Electronic Table of Contents (United Kingdom)

Immune function is critical in health and disease. The control and regulation of immune reactions is an area of intense investigation that has important implications for allogeneic hematopoietic cell transplantation. Immune reactions are regulated in a number of important ways. Compartmentalization of immune responses and the production of both pro-inflammatory and anti-inflammatory cytokines play a major role. More recently several populations of T cells that regulate immune responses termed regulatory T cells have been identified. This manuscript will focus on CD4^+CD25^+FoxP3^+ natural regulatory T cells (T"r"e"g) and @a@bTCR^+CD4^+NK1.1^+ natural killer T (NK-T) cells which both suppress graft vs host disease but appear to function by distinct mechanisms.

2011-01-01

90

Nickel induced structural and functional alterations in mouse Leydig cells in vitro  

British Library Electronic Table of Contents (United Kingdom)

The present study was aimed at investigating effects of nickel (NiCl2) on secretion of testosterone (T), cell viability, ultrastructure and apoptosis in mouse Leydig cells. Testosterone release was measured after 48h of culture with 15.67, 31.25, 62.5, 125, 250, 500 and 1000mmol/L NiCl2 or without NiCl2 using radioimmunoassay. Cell viability was assessed by a MTT (metabolic activity assay). Quantification of apoptotic cells was performed using TUNEL assay and the ultrastructural changes were analyzed using transmission electron microscopy. The viability was decreased after addition of >=250mmol/L NiCl2. A concentration-dependent depression of T production was observed. The percentage of apoptotic cells was significantly increased only after addition of 125, 250 and 1000mmol/L NiCl2. After ...

2011-01-01

91

Estimates of quantitative genetic parameters of immunological traits in the chicken.  

Science.gov (United States)

Three in vivo assays were used to measure the immunocompetence of chickens in two generations of a selection experiment. The obtained data were used to estimate the variance components for sire and dam for antibody production to Pasteurella multocida and Mycoplasma gallisepticum vaccines, for T-cell-mediated immunity evaluated by a phytohemagglutinin wing web assay, and for clearance of foreign particles from the circulatory system. Heritabilities of and genetic correlations among these immunological traits were calculated from the sire variance components. Heritability estimates of the immunological traits based on the sire component of variance ranged from .06 to .53, and genetic correlations among immunological traits were generally negative. PMID:1956847

1991-10-01

92

Decreased semen quality in a male infected with malaria.  

Science.gov (United States)

A 33-year-old male of proven fertility suffered six attacks of malaria while resident in an African country. For this he received anti-malarial drugs. Semen analysis performed after the fourth attack, and repeated during the following 2 years after his return to Israel, revealed severe oligozoospermia, necrozoospermia and occasionally even azoospermia. Immunological examination of the patient revealed an inverse ratio of T-cell subsets and mast cell degranulation in response to palludrin. Twenty-five months after the last attack of malaria a significant improvement was found in semen quality and there was an increase in the ratio of T-helper to T-suppressor cytotoxic cells. These observations indicate that although malaria and its treatment may affect spermatogenesis, recovery may be expected eventually. PMID:3500921

1987-10-01

93

A novel BMT technique for treatment of various currently intractable diseases  

British Library Electronic Table of Contents (United Kingdom)

A recently-developed BMT method combines a ''Perfusion Method'' (PM) for collecting bone marrow cells (BMCs) with the Intra-Bone Marrow (IBM) injection of BMCs (IBM-BMT). As distinct from the conventional aspiration method (AM), the PM allows rapid (within 1 h) collection of BMCs without T cell contamination (T cells < 10%). Therefore, no GvHD occurs. Moreover, the burden on donors, such as back pain, bleeding and infection, can be reduced. Full chimerism can be achieved even with only mild conditioning regimens if IBM-BMT is carried out, since IBM-BMT replaces not only the recipient's hemopoietic stem cells (HSCs) but also mesenchymal stem cells (MSCs) with donor-derived HSCs and MSCs. Using this method, we show that most currently intractable diseases are HSC or MSC disorders, and that t...

2011-01-01

94

Use of carbon stable isotope to investigate chloromethane formation in the electrolytic dechlorination of trichloroethylene  

International Nuclear Information System (INIS)

Carbon stable isotope trichloroethylene ("1"3C TCE) was used to investigate the formation of chloromethane (CM) during the electrolytic dechlorination of trichloroethylene (TCE) at a granular-graphite packed cathode. A method was developed to use a conventional GC/MS to analyze and quantify regular and "1"3C TCE and their dechlorination products. The concentration of a "1"3C compound can be calculated, based on the concentration of its regular counterpart, from the response ratio of two fragments of different mass per charge values from the compounds in a sample and two characteristic MS spectrum ratios: one is the response ratio of the two fragments of the regular compound, and the other is the response ratio of the corresponding fragments of the regular and "1"3C compounds at the same concentrations. The method was used to analyze the regular and "1"3C compounds observed in an experiment of dechlorination in an ammonium acetate solution that contained both ...

2007-03-22

95

Manganese removal using an aerated granular filter  

Energy Technology Data Exchange (ETDEWEB)

Experiments on manganese removal using an aerated granular filter with mean particle size of 3.68 mm and 5.21 mm anthracite were conducted at a filtration rate of 100 m d{sup -1}. Air, with a rate of 0 to 366 m d{sup -1}, was supplied through nozzles positioned 100 mm above the filter column bottom. From the experiments that were conducted, it was found that manganese removal is completed at a pH of 9.6 or above. In addition, the oxidation and removal rate of dissolved manganese were expressed as a first-order reaction. The smaller the filter media particles were, the higher the manganese removal efficiency was. The aeration rate of dissolved oxygen in raw water is sufficient for the manganese removal process. The manganese removal rate increased with time due to the catalytic effect of manganese dioxide (MnO{sub 2}) attached to the media. The x-ray diffraction analysis showed that the solids attached to the filter media were not crystalline but amorphous ...

2007-09-15

96

Desorption of uranium from titanium-activated carbon composite adsorbent with acidic eluent, 2  

Energy Technology Data Exchange (ETDEWEB)

The desorption of uranium from the granular titanium-activated carbon composite adsorbent (concentration of uranium: 25.5 mg/l-Ad), which adsorbed uranium from natural sea water, was examined by the column process with acidic eluent at room temperature. The column operation was able to be carried out without destruction of the granular adsorbent by the generation of the carbon dioxide, and free from disturbance of the eluent flow by precipitate of calcium sulfate dihydrate with sulfuric acid eluent. The amount of acid consumption by the adsorbent was 0.87 eq/l-Ad. The alkaline earth metals were eluted in the range of elution volume below 2l/l-Ad, whereas uranium, iron, and titanium were eluted above 2l/l-Ad. Therefore, uranium was separable from the alkaline earth metals which were adsorbed in the most quantity in the adsorbent. In the range of elution volume 2 to 12l/l-Ad, the percentage of desorbed uranium and the concentration ratio of ...

1984-01-01

97

Large hadron collider set to restart  

CERN Document Server

Large hadron collider set to restart

2009-01-01

98

The AMS-02 electromagnetic calorimeter  

CERN Document Server

The Electromagnetic Calorimeter (ECAL) of the AMS-02 experiment is a lead-scintillating fibers sampling calorimeter characterized by high granularity that allows to image the longitudinal and lateral showers development, a key issue to provide high electron/hadron discrimination. The light collection system and the FE electronics are designed to let the calorimeter operate over a wide energy range from few GeV up to 1 TeV. A full-scale prototype of the e.m. calorimeter was tested at CERN in October 2001 using electrons and pions beams with energy ranging from 3 to 100 GeV. Effective sampling thickness, linearity and energy resolution were measured. (8 refs).

2002-01-01

99

Effect of grain size and pearlite morphology on the components of the fracture energy in steel 45 in the region of the ductile-brittle transition  

Energy Technology Data Exchange (ETDEWEB)

It is known that in size reduction of the granular structure of ferrite and ferrite-pearlite steels the temperature of the transformation from ductile to brittle condition is lowered. This effect can also be caused by an increase in the dispersity of intragrain and intergrain segregations (sulfides, carbonitrides, and segregations of impurity atoms), which accompanies grain size reduction and promotes initiation and propagation of cracks. In order to clarify the mechanism of fracture of steel in the region of the ductile-brittle transition steel 45 with different grain sizes and pearlite morphologies has been investigated.

1995-11-01

100

Depleted zinc: Properties, application, production  

Energy Technology Data Exchange (ETDEWEB)

The addition of ZnO, depleted in the Zn-64 isotope, to the water of boiling water nuclear reactors lessens the accumulation of Co-60 on the reactor interior surfaces, reduces radioactive wastes and increases the reactor service-life because of the inhibitory action of zinc on inter-granular stress corrosion cracking. To the same effect depleted zinc in the form of acetate dihydrate is used in pressurized water reactors. Gas centrifuge isotope separation method is applied for production of depleted zinc on the industrial scale. More than 20 years of depleted zinc application history demonstrates its benefits for reduction of NPP personnel radiation exposure and combating construction materials corrosion.

2009-07-15

101

Silencing of SARS-CoV spike gene by small interfering RNA in HEK 293T cells  

International Nuclear Information System (INIS)

Two candidate small interfering RNAs (siRNAs) corresponding to severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike gene were designed and in vitro transcribed to explore the possibility of silencing SARS-CoV S gene. The plasmid pEGFP-optS, which contains the codon-optimized SARS-CoV S gene and expresses spike-EGFP fusion protein (S-EGFP) as silencing target and expressing reporter, was transfected with siRNAs into HEK 293T cells. At various time points of posttransfection, the levels of S-EGFP expression and amounts of spike mRNA transcript were detected by fluorescence microscopy, flow cytometry, Western blot, and real-time quantitative PCR, respectively. The results showed that the cells transfected with pEGFP-optS expressed S-EGFP fusion protein at a higher level compared with those transfected with pEGFP-S, which contains wildtype SARS-CoV spike gene sequence. The green fluorescence, mean fluorescence intensity, and ...

2004-11-26

102

Steady particulate flows in a horizontal rotating cylinder  

Energy Technology Data Exchange (ETDEWEB)

Results of discrete element method (DEM) simulation and magnetic resonance imaging (MRI) experiments are compared for monodisperse granular materials flowing in a half-filled horizontal rotating cylinder. Because opacity is not a problem for MRI, a long cylinder with an aspect ratio {approximately}7 was used and the flow in a thin transverse slice near the center was studied. The particles were mustard seeds and the ratio of cylinder diameter to particle diameter was approximately 50. The parameters compared were dynamic angle of repose, velocity field in a plane perpendicular to the cylinder axis, and velocity fluctuations at rotation rates up to 30 rpm. The agreement between DEM and MRI was good when the friction coefficient and nonsphericity were adjusted in the simulation for the best fit. {copyright} {ital 1998 American Institute of Physics.}

1998-06-01

103

Sensitization and radiation hardening of the photostimulable X-ray storage phosphor CsBr:Eu2+  

British Library Electronic Table of Contents (United Kingdom)

The X-ray storage phosphor CsBr:Eu2+ in form of needle image plates is believed to be a promising alternative to the granular BaFBr:Eu2+ with regard to PSL yield and spatial resolution. Unfortunately, CsBr:Eu2+ exhibits poor radiation hardness, which is caused by a migration of europium ions initiated by naturally existing defect centers like (Eu2+-VCs)-centers and X-ray generated MEu-centers. It will be shown that the formation of (Eu2+-O2?)-dipoles at the expense of (Eu2+-VCs)-dipoles, incorporated by thermal annealing in O2-containing and humid atmosphere, does not improve the radiation stability. There is, however, a strong improvement in the radiation hardness by codoping of CsBr:Eu2+ with lithium ions, which is accompanied by a complete suppression of the previously observed MEu-cent...

2009-01-01

104

Microstructure and mechanical behaviour of an elevated temperature Mg-rare earth based alloy  

International Nuclear Information System (INIS)

AM-SC1 is a heat treatable magnesium alloy that has been specifically developed to achieve the elevated temperature strength and creep properties necessary for engine block applications. This paper describes the interrelationship between the microstructure and the mechanical properties of AM-SC1. The compressive and tensile strengths are relatively insensitive to temperature up to and including 450 K and the tensile yield behaviour deviates from a standard Hall-Petch relationship at grain sizes below 200 ?m. The microstructural features contributing to the creep resistance are both inter- and intra-granular in nature and are on length scales from nanometers to micrometers. The creep behaviour at 423 K and 450 K is diffusion controlled, with any contribution from the grain boundaries being negligible.

2009-04-15

105

Idaho National Laboratory Supervisory Control and Data Acquisition Intrusion Detection System (SCADA IDS)  

Energy Technology Data Exchange (ETDEWEB)

Current Intrusion Detection System (IDS) technology is not suited to be widely deployed inside a Supervisory, Control and Data Acquisition (SCADA) environment. Anomaly- and signature-based IDS technologies have developed methods to cover information technology-based networks activity and protocols effectively. However, these IDS technologies do not include the fine protocol granularity required to ensure network security inside an environment with weak protocols lacking authentication and encryption. By implementing a more specific and more intelligent packet inspection mechanism, tailored traffic flow analysis, and unique packet tampering detection, IDS technology developed specifically for SCADA environments can be deployed with confidence in detecting malicious activity.

2008-05-01

106

Fragile granular jamming  

Energy Technology Data Exchange (ETDEWEB)

We demonstrate experimentally that the route to a jammed state for a set of bi-dispersed frictional disks, subjected to uni-axial compression from a random initial unjammed state, consists of a consolidation state, a fragile jammed state, and finally a rigid jammed state. In the consolidation regime, the pressure on the sides increases very slowly with the packing fraction {phi} and there are no detectable stress chains. In the fragile jammed state, stress chains are visible, the pressure increases exponentially with {phi}, and the fraction of moving disks drops exponentially. Eventually, a final regime where particle displacements are below our resolution and the pressure varies approximately linearly with {phi} is reached. We argue that this scenario is generic for ather mal frictional compressed particles.

2009-01-01

107

Bactericidal effects of different silver-containing materials  

British Library Electronic Table of Contents (United Kingdom)

The evaluation of the bactericidal effect of different silver-containing materials where silver is available as Ag^+ (silver nitrate and different silver-exchanged zeolites), as metallic Ag^0 (commercial silver nanoparticles) or as oxide (silver (I) oxide) was carried out in order to elucidate the importance of the bioavailability of silver (i.e., as free ions, metallic particles, combination of them, clusters, complexes, partially soluble or insoluble salts, etc.) on its bactericidal action. For the different materials tested, their bactericidal effect is ordered in the following sequence: AgNO"3>Ag-ZSM-5>Ag"2O>commercial silver-exchanged zeolite (granular)>commercial silver-exchanged zeolite (pellets)>Ag nanoparticles. In general, as the content of bioavailable ionic silver increases, th...

2011-01-01

108

Amine treatment and activated charcoal  

Energy Technology Data Exchange (ETDEWEB)

Alkanol-amine is used for removing hydrogen sulfide and carbon dioxide from the gas stream. Contaminated amine is the amine which is contaminated by hydrocarbon, organic acid or iron sulfide, etc.. In addition, in the case when an antifoaming agent is excessively added to it or when it is decomposed chemically or thermally, it is considered that it is contaminated. When an amine solution becomes contaminated, several problems concerning operation control occur which would influence the effect of the amine treatment in consequence. By using activated charcoal, it is possible to decrease the additional amount of the antifoaming agent or corrosion inhibitor. This is because activated charcoal removes the decomposed product which causes the foaming phenomenon. In order to derive economical profit sufficiently, an activated charcoal system properly designed is necessary. In this article, the CALGON CLEANAMINE SYSTEM of Calgon Co. is introduced which restores the effect of amine solution by ...

1988-10-01

109

A He-gas Cooled, Stationary Granular Target  

CERN Document Server

In the CERN approach to the design of a neutrino factory, the repetition frequency of the proton beam is high enough to consider stationary solid targets as a viable solution for multi-MW beams. The target consists of high density tantalum spheres of 2 mm diameter which can efficiently be cooled by passing a high mass flow He-gas stream through the voids between the Ta-granules. Very small thermal shocks and stresses will arise in this fine grained structure due to the relatively long burst of 3.3 ms from the SPL-proton linac. In a quadruple target system where each target receives only one quarter of the total beam power of 4 MW, conservative temperature levels and adequate lifetimes of the target are estimated in its very high radiation environment. A conceptual design of the integration of the target into the magnetic horn-pion-collector is presented.

2003-01-01

110

Regulatory role of neuron-restrictive silencing factor in expression of TRPC1  

International Nuclear Information System (INIS)

Neuron-restrictive silencer factor (NRSF) binds its consensus element to repress the transcription of various genes. The dominant-negative form (dnNRSF) has a hypertrophic effect on cardiogenesis through an unidentified mechanism. We examined the involvement of transient receptor potential (TRP) channel proteins, using transgenic mice overexpressing dnNRSF (dnNRSF mice). Electrophoretic mobility-shift assays revealed an interaction between NRSF and a neuron-restrictive silencer element-like sequence in intron 4 of TRPC1 genomic DNA. According to RT-PCR and Western analyses, TRPC1 was up-regulated in dnNRSF mouse heart. Transient overexpression of TRPC1 in HEK 293T cells increased the activity of the nuclear factor in activated T cells (NFAT) promoter and stimulated store-operated Ca"2"+ channel (SOCC)-mediated Ca"2"+ entry. Transfection of TRPC1 into primary cardiomyocytes increased NFAT activity, indicating a major role for TRPC1 in NFAT ...

2006-12-22

111

Detection of constitutive heterodimerization of the integrin Mac-1 subunits by fluorescence resonance energy transfer in living cells  

International Nuclear Information System (INIS)

Macrophage differentiation antigen associated with complement three receptor function (Mac-1) belongs to #beta#_2 subfamily of integrins that mediate important cell-cell and cell-extracellular matrix interactions. Biochemical studies have indicated that Mac-1 is a constitutive heterodimer in vitro. Here, we detected the heterodimerization of Mac-1 subunits in living cells by means of two fluorescence resonance energy transfer (FRET) techniques (fluorescence microscopy and fluorescence spectroscopy) and our results demonstrated that there is constitutive heterodimerization of the Mac-1 subunits and this constitutive heterodimerization of the Mac-1 subunits is cell-type independent. Through FRET imaging, we found that heterodimers of Mac-1 mainly localized in plasma membrane, perinuclear, and Golgi area in living cells. Furthermore, through analysis of the estimated physical distances between cyan fluorescent protein (CFP) and yellow fluorescent protein (YFP) fused to Mac-1 subunits, we ...

2006-08-04

112

An evaluation of the pendulum technique of electron beam therapy  

International Nuclear Information System (INIS)

Electron beam therapy of lesions such as cutaneous metastatic carcinoma and reticulum cell sarcoma is performed via multiple portals for a wide irradiation field. However, the dose distribution in border areas is generally uneven, resulting in hot and cold dose areas depending on the intervals of the portals. We performed electron irradiation by the pendulum technique, especially on curved areas, and evaluated the technique in various respects. Pendulum electron beam irradiation is indicated when the length of the cone must be reduced in order to deliver the target volume near the skin surface as well as to avoid the occurrence of hot spots deep in the body. We prepared a 15cm rotating cone by cutting a 30cm fixed irradiation cone. The modification posed no disadvantages in terms of extent and flatness of the beam, or stability during rotation. After determining the relationship between the rotation speed and the dose, the technique was successfully applied to a patient with adult ...

113

Toxicity of N-substituted aromatics to acetoclastic methanogenic activity in granular sludge  

Energy Technology Data Exchange (ETDEWEB)

N-substituted aromatics are important priority pollutants entering the environment primarily through anthropogenic activities associated associated with the industrial production of dyes, explosives, pestides, and pharmaceuticals. Anaerobic treatment of wastewaters discharged by these industries could potentially be problematical as a result of the high toxicity of N-substituted aromatics. The objective of this study was to examine the structure-toxicity relationship of N-substituted aromatic compounds to acetoclastic methanogenic bacteria. The toxicity was assayed to serum flasks by measuring methane production in granular sludge. Unacclimated cultures were used to minimize the biotransformation of the toxic organic chemicals during the test. The nature and the degree of the aromatic substitution were observed to have a profound effect on the toxicity of the test compound. Nitroaromatic compounds were, on the average, over 500-fold more toxic than their ...

1995-11-01

114

Regeneration of granular activated carbon using hydrothermal technology  

Energy Technology Data Exchange (ETDEWEB)

The economic feasibility of using granular activated carbon (GAC) to remove organic contaminants from industrial and municipal wastewater is contingent upon its reuse during multiple adsorption-regeneration cycles. The most common process for the regeneration of GAC is the thermal method. Drawbacks associated with thermal regeneration include a 5--10% loss of carbon due to oxidation and attrition, a decrease in adsorption capacity, and high energy costs. The purpose of this study was to investigate the regeneration of GAC using hydrothermal technology. Phenol contaminated and non-contaminated GAC samples were regenerated using supercritical water (411 deg C and 26.2 MPa) with dissolved oxygen concentrations of 0 mg/L, 5 mg/L, and 100 mg/L. For comparative purposes, GAC was regenerated using subcritical water (300 deg C and 12.4 MPa) with a dissolved oxygen concentration of 5 mg/L. Regenerated GAC samples were evaluated in terms of adsorption capacity, BET surface ...

1999-05-01

115

Radiochemical Analyses of the Filter Cake, Granular Activated Carbon, and Treated Ground Water from the DTSC Stringfellow Superfund Site Pretreatment Plant  

Energy Technology Data Exchange (ETDEWEB)

The Department of Toxic Substance Control (DTSC) requested that Lawrence Livermore National Laboratory (LLNL) evaluate the treatment process currently employed at the Department's Stringfellow Superfund Site Pretreatment Plant (PTP) site to determine if wastes originating from the site were properly managed with regards to their radioactivity. In order to evaluate the current management strategy, LLNL suggested that DTSC characterize the effluents from the waste treatment system for radionuclide content. A sampling plan was developed; samples were collected and analyzed for radioactive constituents. Following is brief summary of those results and what implications for waste characterization may be made. (1) The sampling and analysis provides strong evidence that the radionuclides present are Naturally Occurring Radioactive Material (NORM). (2) The greatest source of radioactivity in the samples was naturally occurring uranium. The sample results indicate that the uranium ...

2005-09-16

116

Radiochemical Analyses of the Filter Cake, Granular Activated Carbon, and Treated Ground Water from the DTSC Stringfellow Superfund Site Pretreatment Plant  

International Nuclear Information System (INIS)

The Department of Toxic Substance Control (DTSC) requested that Lawrence Livermore National Laboratory (LLNL) evaluate the treatment process currently employed at the Department's Stringfellow Superfund Site Pretreatment Plant (PTP) site to determine if wastes originating from the site were properly managed with regards to their radioactivity. In order to evaluate the current management strategy, LLNL suggested that DTSC characterize the effluents from the waste treatment system for radionuclide content. A sampling plan was developed; samples were collected and analyzed for radioactive constituents. Following is brief summary of those results and what implications for waste characterization may be made. (1) The sampling and analysis provides strong evidence that the radionuclides present are Naturally Occurring Radioactive Material (NORM). (2) The greatest source of radioactivity in the samples was naturally occurring uranium. The sample results indicate that the uranium concentration ...

117

Large scale magnetic field measurements and mapping  

CERN Document Server

Large scale magnetic field measurements and mapping

1984-01-01

118

Total skin electron beam therapy followed by adjuvant psoralen/ultraviolet-a light in the management of patients with T1 and T2 cutaneous T-cell lymphoma (mycosis fungoides)  

International Nuclear Information System (INIS)

Purpose: Patients with mycosis fungoides [cutaneous T-cell lymphoma (CTCL)] may benefit from adjuvant therapy after completing total skin electron beam therapy (TSEBT). We report the results for (T1(T2)) CTCL patients treated with adjuvant oral psoralen plus ultraviolet light (PUVA) with respect to overall survival (OS), disease-free survival (DFS), salvage of recurrence, and toxicity. Methods and Materials: Between 1974 and 1993, TSEBT was administered to a total of 213 patients with CTCL. Records were reviewed retrospectively, and a total of 114 patients were identified as having T1 or T2 disease. Radiotherapy was provided via a 6-MeV linac to a total of 36 Gy, 1 Gy/day, 4 days/week, for 9 weeks. Beginning in 1988, patients were offered adjuvant PUVA within 2 months of completing TSEBT. This was started at 0.5-2 J/m"2, 1-2 treatments/week, with a taper over 3-6 months. Therapy then continued once per month. There were 39 T1 and 75 T2 patients. Six T1 (15%) and ...

1997-07-15

119

Transportation container for Li/SO/sub 2/ batteries on passenger aircraft  

Energy Technology Data Exchange (ETDEWEB)

A surplus USN 40 mm ammunition can was subjected to a variety of tests. Pressure tests were carried out with nitrogen gas, followed by the venting of actual Li/SO/sub 2/ cells and batteries inside the can. A fire test was also conducted on a can packed with 10 each 10-cell batteries surrounded by vermiculite. Test results indicate the US Navy (USN) 40-mm ammunition can is suitable as a shipping container for Li/SO/sub 2/ batteries on passenger aircraft. To provide a further measure of safety, a sulfur dioxide getter was incorporated into the can. Studies indicated a commercial material, ASC carbon, is suitable for this purpose. The granular material was packaged in porous paper desiccant bags and placed in the can with the batteries and vermiculite. The batteries were vented inside the sealed can and the internal pressure monitored. Pressure returned to normal within several minutes, indicating that this arrangement should prevent sulfur dioxide (SO/sub 2/) gas ...

1987-01-01

120

The use of calcium silicate bricks for retrospective dosimetry  

International Nuclear Information System (INIS)

The suitability of calcium silicate bricks (CSBs) for the retrospective measurement of gamma dose using luminescence techniques has been investigated. Bricks of this type are distinguished from fired clay bricks by containing negligible clay and requiring comparatively low temperature treatment during manufacture. They have been used widely in the construction f buildings in the Former Soviet Union since the 1970s but hitherto have not been used for retrospective dosimetry measurements. A procedure based on the se of the 210 deg. C thermoluminescence (TL) peak of quartz was tested with granular quartz extracted from three types of CSB, one of which had been taken from a settlement downwind of Chernobyl. The degree to which the residual geological TL signal within the temperature range of the 210 deg. C L peak had been reduced during manufacture varied with brick type; the levels of residual TL corresponded, in the samples tested, to absorbed doses n the range ...

2004-02-01

121

The application of high pH operation to the secondary water chemistry at Genkai Nuclear Power Station  

International Nuclear Information System (INIS)

PWR plants have made efforts to maintain the long-term integrity of the steam generators (SG) by reducing the amount of corrosion products entering the secondary side of the SG. Iron entered the SG can cause several problems: degraded heat conductivity of the SG tubes in locations where iron is deposited, water level oscillations in the SG due to tube support plate hole blockage, and initiation and propagation of inter-granular attacks (IGA) and stress corrosion cracking (SCC). One of the most effective measures, high all-volatile treatment (AVT) chemistry has been applied to actual plants to reduce the flow-accelerated corrosion (FAC) coming from the carbon steel piping. The secondary water chemistry at Genkai NPS 1 and 2 changed, from the Low AVT chemistry to the High AVT chemistry, in November 2006. In this paper, we will describe the results of experiments in applying the use of High pH water in the secondary water system at Genkai NPS. (author)

2009-02-01

122

Solid electrolyte and lithium battery employing it. Kotai denkaishitsu oyobi sore wo shiyo shite naru richiumu denchi  

Energy Technology Data Exchange (ETDEWEB)

Recently, the lithium ion-conductive solid electrolyte draws attention because there is a possibility of producing the maintenance-free battery which is characterized by having such advantages as high energy density and no possibility of electrolyte leak because of solid state structure. The invented lithium ion-conductive solid electrolyte is formed by sintering the granular electrolyte expressed in the following general formula: Li(1+(4-n)x)MxTi(2-x)(PO4)3 (M = mono- or di-valent cation, x = 0.1 - 0.5). Examples of the monovalent cation are Na[sup +], K[sup +], Rb[sup +], Cs[sup +], and Cu[sup +]. Examples of divalent cation are Mg[sup 2+], Fe[sup 2+], Be[sup 2+], Ca[sup 2+], Sr[sup 2+], Ba[sup 2+], Ra[sup 2+], Mn[sup 2+], Co[sup 2+], Cu[sup 2+], Ni[sup 2+], Zn[sup 2+], and Cd[sup 2+]. The electric conductivity of lithium ion is increased with the increase in the content of Li[sup +] in the electrolyte. 4 figs.

1993-11-12

123

Sampling and Analysis at the Vortec Vitrification Facility in Paducah, Kentucky. Semiannual report, November 1, 1996--March 31, 1997  

Science.gov (United States)

The Vortec Cyclone Melting System (CMS) facility; to be located at the U.S. Department of Energy (DOE) Paducah Gaseous Diffusion Plant, is designed to treat soil contaminated with low levels of heavy metals and radioactive elements, as well as organic waste. The primary components of Vortec`s CMS are a counter rotating vortex (CRV) reactor and cyclone melter. In the CMS process, granular glass forming ingredients and other feedstocks are introduced into the CRV reactor where the intense CRV mixing allows the mixture to achieve a stable reaction and rapid heating of the feedstock materials. Organic contaminants in the feedstock are effectively oxidized, and the inert inorganic solids are melted. The University of North Dakota Energy {ampersand} Environmental Research Center (EERC) has been contacted to help in the development of sampling plans and to conduct the sampling at the facility. This document is written in a format that assumes that the EERC will perform ...

1997-12-31

124

Life Under Your Feet: An End-to-End Soil Ecology Sensor Network, Database, Web Server, and Analysis Service  

CERN Document Server

Wireless sensor networks can revolutionize soil ecology by providing measurements at temporal and spatial granularities previously impossible. This paper presents a soil monitoring system we developed and deployed at an urban forest in Baltimore as a first step towards realizing this vision. Motes in this network measure and save soil moisture and temperature in situ every minute. Raw measurements are periodically retrieved by a sensor gateway and stored in a central database where calibrated versions are derived and stored. The measurement database is published through Web Services interfaces. In addition, analysis tools let scientists analyze current and historical data and help manage the sensor network. The article describes the system design, what we learned from the deployment, and initial results obtained from the sensors. The system measures soil factors with unprecedented temporal precision. However, the deployment required device-level programming, sensor ...

2007-01-01

125

Hybridization and Modification of the Ni/C{sub 60} Composites  

Science.gov (United States)

Hybridization and thermal evolution of the Ni+C{sub 60} composites, deposited on Si(001) at room temperature, were studied using Scanning Electron Microscopy, {mu}-Raman spectroscopy and Rutherford Backscattering. As-deposited, the hybrid films exhibited a granular nano-structure with Ni nano-particles encapsulated in C{sub 60} polymerized rinds. The Ni and C (C{sub 60}) distributions in a top layer were found homogeneous with a stable Ni/C (C{sub 60}) ratio; in the larger depth the distributions were inhomogeneous and their ratio dramatically varied. At elevated temperatures, all structural parameters were changed. In the subsurface layer Ni- and C (C{sub 60})-rich zones were formed (due to the induced phase separation), C{sub 60}-molecules decayed and their fragments were transformed into amorphous carbon (a-C). The free volume distribution of the stressed hybrid matter was analyzed by the Hg marker that (in a form of vapors) in-diffused in to the samples. The ...

2009-03-10

126

Evaluation of the potential of pentachlorophenol degradation in soil by pulsed corona discharge plasma from soil characteristics.  

Science.gov (United States)

Chlorinated organics are frequently found as harmful soil contaminants and persisted for extended periods of time. A novel approach, named pulsed corona discharge plasma (PCDP), was employed for the degradation of pentachlorophenol (PCP) in soil. Experimental results showed that 87% of PCP could be smoothly removed in 60 min. Increasing pulse voltage, enhancing soil pH, lowering humic acid (HA) in soil and reducing granular size of the soil were found to be favorable for PCP degradation efficiency. Oxidation and physical processes simultaneously contributed to PCP removal in soil and ozone was the main factor in PCDP treatment. C-Cl bonds in PCP were cleaved during PCDP treatment by Fourier transform infrared spectroscopy (FTIR) analysis. The mineralization of PCP was confirmed by total organic carbon (TOC) and dechlorination analyses. The main intermediate products such as tetrachlorocatechol, tetrachlorohydroquinone, acetic acid, formic acid, and oxalic acid were ...

2010-04-15

127

Effects of Mo, Cr, and V Additions on Tensile and Charpy Impact Properties of API X80 Pipeline Steels  

Science.gov (United States)

In this study, four API X80 pipeline steels were fabricated by varying Mo, Cr, and V additions, and their microstructures and crystallographic orientations were analyzed to investigate the effects of their alloying compositions on tensile properties and Charpy impact properties. Because additions of Mo and V promoted the formation of fine acicular ferrite (AF) and granular bainite (GB) while prohibiting the formation of coarse GB, they increased the strength and upper-shelf energy (USE) and decreased the energy transition temperature (ETT). The addition of Cr promoted the formation of coarse GB and hard secondary phases, thereby leading to an increased effective grain size, ETT, and strength, and a decreased USE. The addition of V resulted in a higher strength, a higher USE, a smaller effective grain size, and a lower ETT, because it promoted the formation of fine and homogeneous of AF and GB. The steel that contains 0.3 wt pct Mo and 0.06 wt pct V without Cr had ...

2009-08-01

128

Effects of CdCl2 treatment on properties of CdTe thin films grown by evaporation at low substrate temperatures  

International Nuclear Information System (INIS)

The structural, morphological and optical properties of vacuum-evaporated CdTe thin films were investigated as a function of substrate temperature and post-deposition annealing without and with CdCl2/treatment at 400 C for 30 min. Diffraction patterns are almost the same exhibiting higher preferential orientation corresponding to (111) plane of the cubic phase. The intensity of the (111) peak increased with the CdCl2/annealing treatment. The microstructure observed for all films following the CdCl2/annealing treatment are granular, regardless of the as-deposited microstructure. The grain sizes are increased after the CdCl2/annealing treatment but now contain voids around the grain boundaries. The optical band gaps, Eg, were found to be 1.50, 1.50 and 1.48 eV for films deposited at 200 K and annealed without and with CdCl2/treatment at 400 C for 30 min respectively. A progressive sharpening of the absorption edge upon heat treatment particularly for the ...

2007-09-01

129

Dissolution Kinetics of Zirconia Calcine  

International Nuclear Information System (INIS)

Liquid radioactive raffinates from nuclear fuel reprocessing at the Idaho National Engineering and Environmental Laboratory were solidified, or calcines, in a fluidized bed reactor at approximately 500 C to form a dry granular material. This calcine has been provisionally stored near-surface in concrete-encased stainless steel bins at the Idaho Nuclear Technology Engineering Center. Research addressing the permanent immobilization of radioactive waste has been ongoing. One option is to separate the radioactive constituents from the calcine, thereby reducing the radioactive waste volume to be ultimately stored at a national nuclear waste repository. Nitric acid dissolution of the calcine is a key front-end unit operation in the separations option. In order to design calcine dissolution equipment, quantification of dissolution reaction rate parameters is required. A pilot-plant-produced, non-radioactive calcine was utilized to study the dissolution kinetics of a ...

130

Characterization and gas-sensing behavior of an iron oxide thin film prepared by atomic layer deposition  

International Nuclear Information System (INIS)

In this work we investigate an iron oxide thin film grown with atomic layer deposition for a gas sensor application. The objective is to characterize the structural, chemical, and electrical properties of the film, and to demonstrate its gas-sensitivity. The obtained scanning electron microscopy and atomic force microscopy results indicate that the film has a granular structure and that it has grown mainly on the glass substrate leaving the platinum electrodes uncovered. X-ray diffraction results show that iron oxide is in the #alpha#-Fe_2O_3 (hematite) phase. X-ray photoelectron spectra recorded at elevated temperature imply that the surface iron is mainly in the Fe"3"+ state and that oxygen has two chemical states: one corresponding to the lattice oxygen and the other to adsorbed oxygen species. Electric conductivity has an activation energy of 0.3-0.5 eV and almost Ohmic current-voltage dependency. When exposed to O_2 and CO, a typical n-type response is ...

2008-07-31

131

Changes in cell proliferation kinetics in the mouse cerebellum after total asphyxia  

International Nuclear Information System (INIS)

This study was undertaken to investigate the effects of neonatal asphyxia on brain development, with special reference to the kinetics of neuronal proliferation by using autoradiography. For 30 minutes, two-day-old suckling mice, Jcl:ICR strain, were put into a chamber which was constantly flushed with 100% CO_2 gas. After the exposure to asphyxia, 29% of the mice survived. Cell cycle studies were carried out at two days and at seven days on the external matrix cells, the precursor of the granule cells, at the external granular layer of the cerebellum from CO_2-exposed and control mice by "3H-thymidine autoradiography. At two days the generation time of the control mice was about 15 hours, whereas that of the asphyxiated mice was about 17 hours. The prolongation of the generation time in the asphyxiated mice was caused mainly by a delay in the G2 phase. This prolongation was apparent for about five days and thereafter growth caught up. These results suggest that ...

132

Calcination of Fluorinel-sodium waste blends using sugar as a feed additive (formerly WINCO-11879)  

Energy Technology Data Exchange (ETDEWEB)

Methods were studied for using sugar as a feed additive for converting the sodium-bearing wastes stored at the Idaho Chemical Processing Plant into granular, free flowing solids by fluidized-bed calcination at 500{degrees}C. All methods studied blended sodium-bearing wastes with Fluorinel wastes but differed in the types of sugar (sucrose or dextrose) that were added to the blend. The most promising sugar additive was determined to be sucrose, since it is converted more completely to inorganic carbon than is dextrose. The effect of the feed aluminum-to-alkali metal mole ratio on calcination of these blends with sugar was also investigated. Increasing the aluminum-to-alkali metal ratio from 0.6 to 1.0 decreased the calcine product-to-fines ratio from 3.0 to 1.0 and the attrition index from 80 to 15%. Further increasing the ratio to 1.25 had no effect.

1992-06-01

133

Biosorption of heavy metals from wastewater by biosolids  

Energy Technology Data Exchange (ETDEWEB)

In a study where the removal of heavy metals from wastewater is the primary aim, the biosorption of heavy metals onto biosolids prepared as Pseudomonas aeruginosa immobilized onto granular activated carbon was investigated in batch and column systems. In the batch system, adsorption equilibriums of heavy metals were reached between 20 and 50 min, and the optimal dosage of biosolids was 0.3 g/L. The biosorption efficiencies were 84, 80, 79, 59 and 42 % for Cr(VI), Ni(II), Cu(II), Zn(II) and Cd(II) ions, respectively. The rate constants of biosorption and pore diffusion of heavy metals were 0.013-0.089 min{sup -1} and 0.026-0.690 min{sup -0.5}. In the column systems, the biosorption efficiencies for all heavy metals increased up to 81-100 %. The affinity of biosorption for various metal ions towards biosolids was decreased in the order: Cr = Ni > Cu > Zn > Cd. (Abstract Copyright [2006], Wiley Periodicals, Inc.)

2006-08-15

134

Batch test equilibration studies examining the removal of Cs, Sr, and Tc from supernatants from ORNL underground storage tanks by selected ion exchangers  

Energy Technology Data Exchange (ETDEWEB)

Bench-scale batch equilibration tests have been conducted with supernatants from two underground tanks at the Melton Valley Storage Tank (MVST) Facility at Oak Ridge National Laboratory (ORNL) to determine the effectiveness of selected ion exchangers in removing cesium, strontium, and technetium. Seven sorbents were evaluated for cesium removal, nine for strontium removal, and four for technetium removal. The results indicate that granular potassium cobalt hexacyanoferrate was the most effective of the exchangers evaluated for removing cesium from the supernatants. The powdered forms of sodium titanate (NaTiO) and cystalline silicotitanate (CST) were superior in removing the strontium; however, for the sorbents of suitable particle size for column use, titanium monohydrogen phosphate (TiHP {phi}), sodium titanate/polyacrylonitrile (NaTiO-PAN), and titanium monohydrogen phosphate/polyacrylonitrile (TiP-PAN) gave the best results and were about equally effective. ...

1995-06-01

135

Application of base-level cycles to sandstone-type uranium deposit: taking Dongsheng uranium deposits as an example  

International Nuclear Information System (INIS)

High-resolution sequence stratigraphy taking base-level cycles as interface of reference was developed rapidly in recent years. Its greatest predominance lies in that it can be applied to multi-controled continental sedimentary basins and can effectively improve accuracy and distinguishability of sequence stratigraphy analysis. Principles of base-level cycles can also be applied to the research and practice of the exploration and exploitation of sandstone-type uranium deposits as they control the spatial distribution, porosity, the permeability and the sealing ability of sandstone and mudstone, and stacking patterns of strata configuration. Taking Dongsheng uranium deposits as an example, the application of base-level cycles to exploration and exploitation of sandstone uranium deposits was analyzed. It is suggested that favorable strata framework of sandstone and mudstone was developed very well in the fluctuation of base-level cycles. Sand bodies were provided with good connectedness, ...

2006-05-01

139

The Large Hadron Collider and the Long-Term Scientific programme of CERN: Executive Summary  

CERN Document Server

The Large Hadron Collider and the Long-Term Scientific programme of CERN: Executive Summary

1993-01-01

140

Validation of immune function testing during a 4-week oral toxicity study with FK506.  

Science.gov (United States)

Assessment of the immune system's capability to respond to antigens with the generation of specific antibodies, whilst under the influence of a test article, is required in toxicity tests according to the European guideline for repeated dose toxicity testing of medicinal products. The purpose of this study in rats was to validate methodology for the determination of Keyhole Limpet Haemocyanin (KLH)-specific antibodies under the influence of an immunologically active compound. The immunosuppressant FK506, commercially available as Prograf, was administered orally (gavage) to five rats per sex per group at dosages of 0.5mg/kg per day or 3mg/kg per day, for a period of 4 weeks. On days 14 and 22, KLH was administered subcutaneously, with an adjuvant (AluGel), to the two treated groups and a control (i.e. without FK506 treatment) approximately 1h following administration of FK506. Terminal investigations included haematology parameters, titration of KLH-specific antibodies in serum ...

2004-04-01

141

Photoaffinity labeling of ATP and NAD"+ binding sites on recombinant human interleukin 2  

International Nuclear Information System (INIS)

Interleukin 2 (IL-2) is a T-cell-derived lymphokine critical in the activation and proliferation of T cells, B cells, and lymphokine-activated killer cells. It is a glycoprotein of #approx#15,500 daltons that is synthesized and secreted after activation by antigen or mitogen. By using the analogs 8-azidoadensoine 5'-[#gamma#-"3"2P]triphosphate ([#gamma#-"3"2P]8N_3ATP) and nicotinamide 2-azidoadenine [adenylate-"3"2P]dinucleotide ([#alpha#-"3"2P]2N_3NAD"+) as photoaffinity probes, the authors have detected specific, metal ion-requiring nucleotide binding sites on recombinant human IL-2 (rhIL-2). The specificity of these nucleotide interactions with rhIL-2 was demonstrated by saturation effects and by competition by the parent nucleotides at physiologically relevant concentrations. Saturation of photoinsertion into rhIL-2 occurred at 50 #mu#M [#gamma#-"3"2P]8N_3ATP. Saturation of photoinsertion with [#alpha#-"3"2P]2N_3NAD"+ was observed at 180 #mu#M. The extent of ...

142

Inhibitor of DNA synthesis is present in normal chicken serum  

Energy Technology Data Exchange (ETDEWEB)

The authors have found that heat-inactivated serum (57/sup 0/C for 1 hour) from normal chickens reduces the proliferation of mitogen-stimulated chicken and murine splenocytes as well as some transformed mammalian lymphoblastoid cell lines. Greater than a 50% reduction in /sup 3/H-thymidine incorporation was observed when concanavalin A (Con A)-activated chicken splenocytes that were cultured in the presence of 10% autologous or heterologous serum were compared to mitogen-stimulated cells cultured in the absence of serum. Normal chicken serum (10%) also caused greater than 95% suppression of /sup 3/H-thymidine incorporation by bovine (EBL-1 and BL-3) and gibbon ape (MLA 144) transformed lymphoblastoid cell lines. The only cell line tested that was not inhibited by chicken serum was an IL-2-dependent, murine cell line. Chicken serum also inhibited both /sup 3/H-thymidine incorporation and IL-2 synthesis by Con A-activated murine splenocytes. Suppression was caused by actions other than ...

1986-03-05

143

Host resistance to rat cytomegalovirus (RCMV) and immune function in adult PVG rats fed herring from the contaminated Baltic Sea  

Energy Technology Data Exchange (ETDEWEB)

We carried out a feeding study in rats aimed at extending our aboservations of contaminant-induced immunosuppression in harbour seals. Two herring batches were freeze-dried, supplemented and fed to female adult PVG rats for a period of 4 1/2 months. Daily contaminant intakes of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) toxic equivalents (TEQ) were estimated to be 0.3 ng/kg body weight and 1.6 ng/kg in the Atlantic and Baltic groups, respectively. At the end of the feeding experiment, no contaminant-related changes in spleen CD{sub 4}{sup +}/CD{sub 8}{sup +} cellularity, natural killer cell activity, or mitogen-induced proliferative responses of thymus or spleen cells could be detected. However, total thymocyte numbers and thymus CD{sub 4}{sup +}/CD{sub 8}{sup +} ratios were reduced in the Baltic group. A novel model was established to assess the specific T-cell response to rat cytomegalovirus (RCMV). When applied to the feeding study, no differences between the ...

1996-08-01

144

Expression of SV40 virus large T antigen by recombinant adenoviruses activates proliferation of corneal endothelium in vitro.  

UK PubMed Central (United Kingdom)

Infection with the Ad5-SVR4 virus was used to introduce the large T antigen encoding region of the SV40 virus into bovine and human corneal endothelial cells. Expression of large T antigen occurred...Full Text Available

1993-04-01

145

Xanthogranulomatous Salpingitis Associated with a Large Uterine Leiomyoma  

UK PubMed Central (United Kingdom)

A case of xanthogranulomatous salpingitis (XGS) associated with a large uterine leiomyoma in a 50-year-old woman is presented. Xanthogranulomatous inflammation is an uncommon form of chronic inflammation...Full Text Available

2010-01-01

146

Stress Coatings for Large Scale Membrane Mirrors (preprint)  

Science.gov (United States)

... Mirrors (Preprint) Ryan Conk et al. 15 September 2006 ... 4. TITLE AND SUBTITLE Stress Coatings for Large Scale Membrane Mirrors (Preprint) 5a. ...

2006-09-15

147

Real-time digital libraries based on widely distributed, high performance management of large-data-objects  

CERN Document Server

Real-time digital libraries based on widely distributed, high performance management of large-data-objects

1997-01-01

148

Modeling the Internet's large-scale topology  

UK PubMed Central (United Kingdom)

Network generators that capture the Internet's large-scale topology are crucial for the development of efficient routing protocols and modeling Internet traffic. Our ability to design realistic generators...Full Text Available

2002-10-15

149

Derivation of an Extra-Large PASGT Helmet  

Science.gov (United States)

... The solution used on the size Large helmet war an arbitrary one; as discussed above, the developers added a standard deviation to ... 4 O. i3a: o.04. ...

1988-07-01

150

Beach Erosion and Preventive Countermeasure at Kangnan Coast, Taiwan  

Science.gov (United States)

... passed through Hsinchu, causing large waves: Mindulle (2004), Aere (2004) and Haitang (2005). These large, high-energy ... ...

151

Automated NDT for large diameter tubular products  

International Nuclear Information System (INIS)

Ultrasonic and eddy-current techniques are used to automatically examine large diameter tubular products during their production for defective areas and out-of-tolerance conditions.

1976-09-06

152

Are Large Scale (Brigade Combat Team or Regimental Level ...  

Science.gov (United States)

... five newly created airborne divisions, 82nd, 101st, 11th ... completed large scale airborne operations in ... Although division-sized airborne operations ...

2008-04-15

153

The role of acid incubation in rapid immobilization of hydrogen-producing culture in anaerobic upflow column reactors  

Energy Technology Data Exchange (ETDEWEB)

An approach of acidification was examined on formation of hydrogen-producing granules and biofilms in upflow column-shaped reactors. The reactors were fed with synthetic glucose wastewater and operated at 37 C and pH 5.5. The acclimated anaerobic culture was inoculated in four reactors designated R1, R2, R3 and R4, with R3 and R4 filled with granular activated carbon as support medium. To unveil the roles of acidification, microbial culture in R2 and R3 was subject to an acid incubation for 24 h by shifting the culture pH from 5.5 to 2.0. The experimental results suggested that the acidification substantially accelerated microbial granulation, but not biofilm formation. Microbial activities were inhibited by the acid incubation for about 78 h, resulting in the retarded formation of biofilms of the acidified culture. Reducing culture pH resulted in improvement in cell surface physicochemical properties favoring microbial adhesion and immobilization. Zeta potential ...

2008-10-15

154

Protein-coding and non-coding gene expression analysis in differentiating human keratinocytes using a three-dimensional epidermal equivalent.  

Science.gov (United States)

The epidermal compartment is complex and organized into several strata composed of keratinocytes (KCs), including basal, spinous, granular, and cornified layers. The continuous process of self-renewal and barrier formation is dependent on a homeostatic balance achieved amongst KCs involving proliferation, differentiation, and cell death. To determine genes responsible for initiating and maintaining a cornified epidermis, organotypic cultures comprised entirely of stratified KCs creating epidermal equivalents (EE) were raised from a submerged state to an air/liquid (A/L) interface. Compared to the array profile of submerged cultures containing KCs predominantly in a proliferative (relatively undifferentiated) state, EEs raised to an A/L interface displayed a remarkably consistent and distinct profile of mRNAs. Cultures lifted to an A/L interface triggered the induction of gene groups that regulate proliferation, differentiation, and cell death. Next, differentially ...

2010-05-25

155

Proceedings of the workshop on high resolution computed microtomography (CMT)  

Energy Technology Data Exchange (ETDEWEB)

The purpose of the workshop was to determine the status of the field, to define instrumental and computational requirements, and to establish minimum specifications required by possible users. The most important message sent by implementers was the remainder that CMT is a tool. It solves a wide spectrum of scientific problems and is complementary to other microscopy techniques, with certain important advantages that the other methods do not have. High-resolution CMT can be used non-invasively and non-destructively to study a variety of hierarchical three-dimensional microstructures, which in turn control body function. X-ray computed microtomography can also be used at the frontiers of physics, in the study of granular systems, for example. With high-resolution CMT, for example, three-dimensional pore geometries and topologies of soils and rocks can be obtained readily and implemented directly in transport models. In turn, these geometries can be used to calculate ...

1997-02-01

156

Preliminary study on zinc-air battery using zinc regeneration electrolysis with propanol oxidation as a counter electrode reaction  

Energy Technology Data Exchange (ETDEWEB)

A zinc-air battery using zinc regeneration electrolysis with propanol oxidation as a counter electrode reaction is reported in this paper. It possesses functions of both zincate reduction and electrochemical preparation, showing the potential for increasing the electronic energy utilization. Charge/discharge tests and scanning electron microscopy (SEM) micrographs reveal that when a nickel sheet plated with the high-H{sub 2}-overpotential metal, cadmium, was used as the negative substrate electrode, the dendritic formation and hydrogen evolution are suppressed effectively, and granular zinc deposits become larger but relatively dense with the increase of charge time. The performance of batteries is favorable even if the charge time is as long as 5 h at the current density of 20 mA cm{sup -2}. Better discharge performance is achieved using a 'cavity-opening' configuration for the discharge cell rather than a 'gas-introducing' ...

2009-03-01

157

In situ scanning tunneling microscopy study of the structure of the hydroxylated anodic oxide film formed on Cr(110) single-crystal surfaces  

Energy Technology Data Exchange (ETDEWEB)

The structure of hydroxylated oxide films (passive films) formed on Cr(110) in 0.5 M H{sub 2}SO{sub 4} at +0.35, +0.55, and +0.75 V/SHE has been investigated by in situ scanning tunneling microscopy (STM). Cathodic reduction pretreatments at {minus}0.54, {minus}0.64, and {minus}0.74 V/SHE destroy the well-defined topography of the single-crystal electrode and they have been excluded from the passivation procedure. Two different passive film structures have been observed, depending on the potential and time of passivation. At low potential (+0.35 V/SHE), the passive film, consisting mostly of chromium hydroxide, has a noncrystalline and granular structure whose roughness suggests local variations of thickness of ca. {+-} 0.5 nm. A similar structure is observed at higher potential (+0.55 V/SHE), but only for a short polarization time. For longer polarization at 0.55 V/SHE, and at higher potentials (+0.75 V/SHE), a crystalline structure is formed; the higher the ...

1999-09-16

158

Continuous detoxification, transformation, and degradation of nitrophenols in upflow anaerobic sludge blanket (UASB) reactors  

Science.gov (United States)

The anaerobic transformation and degradation of nitrophenols by granular sludge was investigated in upflow anaerobic sludge blanket (UASB) reactors continuously fed with a volatile fatty acid (VFA) mixture as the primary substrate. During the start-up, subtoxic concentrations of 2-nitrophenol (2-NP), 4-nitrophenol (4-NP), and 2, 4-dinitrophenol (2, 4-DNP) were utilized. 4-NP and 2, 4-DNP were readily converted to the corresponding aromatic amine; whereas 2-NP was converted to nonaromatic products via intermediate formation of 2-aminophenol (2-AP). These conversions led to a dramatic detoxification of the mononitrophenols because the reactors treated the nitrophenolics at the concentrations which were over 25 times higher than those that caused severe inhibition. VFA removal efficiencies greater than 99% were achieved in both reactors at loading rates greater than 11.4 g COD per liter of reactor volume per day even at volumetric loading of mononitrophenols up to 910 ...

1996-08-20

159

Colloid retention in porous media of various porosities: predictions by the hemispheres-in-cell model.  

Science.gov (United States)

The hemispheres-in-cell model for colloid transport and deposition in simple granular filtration media preserves the utilities provided in the Happel sphere-in-cell but also incorporates features (e.g., grain-to-grain contact) that are shown to drive colloid deposition from experiments and simulations when colloid-surface repulsion exists (Ma, H.; Pedel, J.; Fife, P.; Johnson, W. P. Environ. Sci. Technol., 2009, in press). The capability of the hemispheres-in-cell model to predict colloid deposition in the absence of repulsive energy barriers for different particle sizes and fluid flow velocities was previously examined (Ma, H.; Pedel, J.; Fife, P.; Johnson, W. P. Environ. Sci. Technol., 2009, in press). In this article, we examine the influence of porosity on colloid deposition in terms of theoretical (simulated) collector efficiencies from the hemispheres-in-cell model, as well as existing models, to examine whether expected trends in porosity are similar among ...

2010-02-01

160

Clinical use of lipiodol in hepatic arteriography  

Energy Technology Data Exchange (ETDEWEB)

Lipiodol, lipid soluble contrast media, was applied to 59 patients, who was clinically suspected to have hepatic tumor, in the Department of Diagnostic Radiology, Seoul National University Hospital. The results of the clinical use of Lipiodol were as follows: 1. The clinical diagnosis was hepatocellular carcinoma (HCC) in 50 cases, cavernous hemangioma in 4 cases, metastasis in one case and others in 4 cases. 2. After hepatic arteriography, Lipiodol only was injected in 28 cases, mixture of Lipiodol and Mitomycin was injected in 22 cases and transcatheter arterial embolization was performed additionally after injection of Lipiodol and Mitomycin in 9 cases. 3. Among the 50 cases of HCC, Lipiodol was accumulated in the lesion in 49 cases. However, similar accumulation of Lipiodol occured in a metastatic cancer and cavernous hemangiomas. 4. Plain radiographic patterns of Lipiodol accumulation could be divided into fine granular type, nodular type and linear or ...

1986-08-15

163

Rubomycine Production  

International Science & Technology Center (ISTC)

Development of Experimental Large-scale Technology and Creation of Technological Line of Rubomicine Production

171

Needs, opportunities, and options for large scale systems research  

Energy Technology Data Exchange (ETDEWEB)

The Office of Energy Research was recently asked to perform a study of Large Scale Systems in order to facilitate the development of a true large systems theory. It was decided to ask experts in the fields of electrical engineering, chemical engineering and manufacturing/operations research for their ideas concerning large scale systems research. The author was asked to distribute a questionnaire among these experts to find out their opinions concerning recent accomplishments and future research directions in large scale systems research. He was also requested to convene a conference which included three experts in each area as panel members to discuss the general area of large scale systems research. The conference was held on March 26--27, 1984 in Pittsburgh with nine panel members, and 15 other attendees. The present report is a summary of the ideas presented and the ...

1984-10-01

172

Treatment of large proximal ureteral stones: extra corporeal shock wave lithotripsy versus semi-rigid ureteroscope with lithoclast  

UK PubMed Central (United Kingdom)

PurposeAssessment of safety and efficacy of extracorporeal shockwave lithotripsy versus semi-rigid ureteroscope with lithoclast for treatment of large proximal ureteral stones.Materials...Full Text Available

173

Treatment of large lumbar disc herniation with percutaneous ozone injection via the posterior-lateral route and inner margin of the facet joint  

UK PubMed Central (United Kingdom)

AIM: To evaluate the effects of percutaneous ozone injection via the posterior-lateral route and inner margin of the facet joint in the treatment of large lumbar disc herniation.METHODS:...Full Text Available

2010-03-28

174

The physical and mental health of a large military cohort: baseline functional health status of the Millennium Cohort  

UK PubMed Central (United Kingdom)

Background:The US military is currently involved in large, lengthy, and complex combat operations around the world. Effective military operations require optimal health of deployed...Full Text Available

175

Shield-verification survey of a large hot cell at the FFTF  

Energy Technology Data Exchange (ETDEWEB)

This paper describes a radiation shield verification survey of a large hot cell at the Fast Flux Test Facility (FFTF). The following aspects of the shield test are discussed: description of the FFTF; description of the hot cell; the test procedures; radiation protection, and the test results.

1980-01-01

176

Quantum chaos in the mixmaster universe  

International Nuclear Information System (INIS)

A Monte Carlo simulation of the vacuum Bianchi type-IX (mixmaster) cosmology yields a significant correlation between large universe volume and high anisotropy. An analog of the model's chaotic classical behavior is seen in the break up of the universe wave function at large volume into fingers in the corners of the minisuperspace anisotropy potential.

177

Proton Transfer Reactivity of Large Multiply Charged Ions  

UK PubMed Central (United Kingdom)

Charge-charge interactions dramatically influence the dissociation and proton transfer reactivity of large multiply protonated ions. In combination with tandem mass spectrometry, proton transfer...Full Text Available

1996-08-01

178

Prognostic determinants for survival after resection/ablation of a large hepatocellular carcinoma  

UK PubMed Central (United Kingdom)

Background:Liver resection of large hepatocellular carcinomas (HCC), measuring at least 10 cm remains a controversial debate. Multiple studies on HCCs treated with surgical resection...Full Text Available

2009-06-01

179

Numerical simulations of quantized Bianchi type IX cosmological models  

International Nuclear Information System (INIS)

This paper reports on Monte Carlo path integral simulations of a Bianchi Type IX cosmology which yield a wave function which reflects the known chaotic dynamics of the classical system and predicts a significant probability for a correlation between large universe volume and large anisotropy.

1988-08-08

180

Large-scale cross-species oncogenomics identifies candidate oncogenes and tumor suppressor genes  

UK PubMed Central (United Kingdom)

While genomic alterations identified in human tumors using techniques such as comparative genomic hybridisation (CGH) may be recurrent, they frequently encompass large regions, in some cases...Full Text Available

2010-02-01

181

Large-Scale Advanced Propfan ... - NASA Technical Reports Server  

Science.gov (United States)

STRESS. VIBRATION DISTRIBUTION FATIGUE FOD. BLADE. X. X. X. X. HUB. X. X. X. SPINNER. X. X. X. Figure 21. - Large scale component test matrix. ...

182

Large plasmids of fast-growing rhizobia: homology studies and location of structural nitrogen fixation (nif) genes.  

UK PubMed Central (United Kingdom)

A single large plasmid was isolated from multiplasmid-harboring strains Rhizobium leguminosarum 1001 and R. trifolii 5. These single plasmids, as well as the largest plasmid detectable in R. phaseoli...Full Text Available

1981-03-01

183

Insights into the Genome of Large Sulfur Bacteria Revealed by Analysis of Single Filaments  

UK PubMed Central (United Kingdom)

Marine sediments are frequently covered by mats of the filamentous Beggiatoa and other large nitrate-storing bacteria that oxidize hydrogen sulfide using either oxygen or nitrate, which...Full Text Available

2007-09-01

184

Detrusor overactivity is associated with downregulation of large-conductance calcium- and voltage-activated potassium channel protein  

UK PubMed Central (United Kingdom)

Large-conductance voltage- and calcium-activated potassium (BK) channels have been shown to play a role in detrusor overactivity (DO). The goal of this study was to determine whether bladder outlet...Full Text Available

2010-06-01

185

Design and Implementation of an Open Source Indexing Solution for a Large Set of Radiological Reports and Images  

UK PubMed Central (United Kingdom)

This paper hopes to share the insights we experienced during designing, building, and running an indexing solution for a large set of radiological reports and images in a production environment for...Full Text Available

2007-11-01

186

A new method for 2D gel spot alignment: application to the analysis of large sample sets in clinical proteomics  

UK PubMed Central (United Kingdom)

BackgroundIn current comparative proteomics studies, the large number of images generated by 2D gels is currently compared using spot matching algorithms. Unfortunately, differences...Full Text Available

187

46 CFR 120.354 - Battery installations.  

Science.gov (United States)

... 2010-10-01 2010-10-01 false Battery installations. 120.354 Section 120...Sources and Distribution Systems § 120.354 Battery installations. (a) Large batteries. Each large battery installation...

2010-10-01

188

Carbon Bed Mercury Emissions Control For Mixed Waste Treatment  

International Nuclear Information System (INIS)

Mercury has had various uses in nuclear fuel reprocessing and other nuclear processes, and so is often present in radioactive and mixed (both radioactive and hazardous according to the Resource Conservation and Recovery Act) wastes. Depending on regulatory requirements, the mercury in the off-gas must be controlled with sometimes very high efficiencies. Compliance to the Hazardous Waste Combustor (HWC) Maximum Achievable Control Technology (MACT) standards can require off-gas mercury removal efficiencies up to 99.999% for thermally treating some mixed waste streams. Several test programs have demonstrated this level of off-gas mercury control using fixed beds of granular sulfur-impregnated activated carbon. Other results of these tests include: (a) The depth of the mercury control mass transfer zone was less than 15-30 cm for the operating conditions of these tests, (b) MERSORB(reg_sign) carbon can sorb Hg up to 19 wt% of the carbon mass, and (c) the spent carbon ...

2010-11-01

189

White dwarfs  

Energy Technology Data Exchange (ETDEWEB)

A large majority of stars and their lines are white dwarfs, the ultimate stellar stage whose structure and properties still fascinate astrophysicists.

1985-04-01

190

Vibration Transmissibility Characteristics of Occupied ...  

Science.gov (United States)

... The relatively large, low frequency multi-axis motions observed at the chest may be a contributor to discomfort in locomotive engineers. ...

2006-09-01

192

The Macro Model of the Inequality Process and The Surging Relative Frequency of Large Wage Incomes  

CERN Document Server

This paper presents a model of the dynamics of the wage income distribution.

2007-01-01

193

The DIVAD Archaeological Project  

Science.gov (United States)

... Like other surveys in the Hueco Bolson (Carmichael 1983; Whalen 1977, 1978), the BLM survey identified large concentrations of Pueblo period ...

2011-05-14

194

Tactical Mobility Modeling for REFORGER 87  

Science.gov (United States)

... The SMSP makes predictions based on historical precipitation data, precipitation ... are characterized by relatively large areas of strategic interest. ...

1992-08-01

195

Superconducting Switchable Circulator  

Science.gov (United States)

... as time delay shifters for large-area phased arrays in military (MILSTAR) as well as commercial (Sky phone and other satellite communication) systems, ...

196

Sidelobe Suppression in an Acousto-Optic Filer with a Raised ...  

Science.gov (United States)

... Abstract : The acousto-optic filter (AOF) is ... for large switch networks. ... FOURIER TRANSFORMATION, OPTICAL SWITCHING, SURFACE ACOUSTIC ...

1992-04-01

197

Research in Reliability, Availability and Maintainability for ...  

Science.gov (United States)

... Effect of checkpointing and queueing on program performance ... and a large class of stochastic linear ... problem is intrinsically related to K-terminal ...

1990-01-01

198

Physical Sciences  

Science.gov (United States)

hicle [UUV (essentially, a small ex- ploratory submarine robot)] of a type that has been deployed in large numbers in research pertaining to global warm- ...

200

Optical Processing and Control  

Science.gov (United States)

... the application of an acousto- optical tunable filter ... Couplers for Large Switch-Array Applications ... Symmetric Integrated Optic X Junction," Electronics ...

1994-01-01

201

NASA TECH BRIEF  

Science.gov (United States)

Magnetic Forming Studies. The use of transient high magnetic-field devices has made possible the generation of very large accurately ...

204

JW" rV-- - NASA  

Science.gov (United States)

roller bearing strength suffi- cient to support efficient, rolling friction movement, even in the presence of large, resisting forces. ...

205

Early Season Applications of Fluridone for Control of Curlyleaf ...  

Science.gov (United States)

... While the large tanks served to regulate the water temper- ature, the polypropylene aquaria served as independent experimental units. ...

2010-12-01

206

Biology-Inspired Distributed Consensus in Massively-Deployed Sensor Networks  

Science.gov (United States)

Promises of ubiquitous control of the physical environment by large-scale wireless sensor networks

2005-01-01

207

Advances and challenges of wood polymer composites  

Science.gov (United States)

... polypropylene, polylactic acid and polyvinyl chloride to form wood plastic composites (WPC). WPCs have seen a large growth in ... ...

208

The physics of production, acceleration and neutralization of large negative ion beams  

Energy Technology Data Exchange (ETDEWEB)

Neutral beam systems for the next generation of magnetic fusion devices will be based on negative ions. Development are progressing steadily, and large negative ion-based systems are prepared for JT60-U and LHD, and are being considered for ITER. An overview of the physics of the production, acceleration and neutralization of large negative ion beams is given. the present state of the art in Research and Development is also surveyed. (author). 55 refs., 10 figs., 1 tab.

1995-12-31

209

The physics of production, acceleration and neutralization of large negative ion beams  

Energy Technology Data Exchange (ETDEWEB)

Neutral beam systems for the next generation of magnetic fusion devices will be based on negative ions. Developments are progressing steadily, and large negative ion-based systems are under preparation for JT60-U and LHD, and are being considered for ITER. An overview of the physics of the production, acceleration and neutralization of large negative ion beams is given. The present state of the art in R and D is also surveyed. (Author).

1995-11-01

210

Performance of a large Bragg-curve spectrometer  

Energy Technology Data Exchange (ETDEWEB)

A large Bragg-curve spectrometer has been constructed and tested. The detector has a cylindrical geometry and operates with a homogeneous electric field. Energy resolutions of <0.8% and Z resolutions of Z/..delta..Z=80 have been achieved for eleastically scattered /sup 58/Ni ions. These results demonstrate the suitability of this large solid-angle detector for use in a wide variety of heavy-ion scattering experiments.

1987-04-01

211

Performance of a large Bragg-curve spectrometer  

International Nuclear Information System (INIS)

A large Bragg-curve spectrometer has been constructed and tested. The detector has a cylindrical geometry and operates with a homogeneous electric field. Energy resolutions of <0.8% and Z resolutions of Z/#DELTA#Z=80 have been achieved for eleastically scattered "5"8Ni ions. These results demonstrate the suitability of this large solid-angle detector for use in a wide variety of heavy-ion scattering experiments. (orig.).

212

On Feynman scaling at large rapidities  

International Nuclear Information System (INIS)

In this work we extend our previous analysis concerning the behavior of inelasticity at high energies and discuss the energy dependence of rapidity distributions giving special attention to large rapidities. We conclude that the U A5 and U A 7 data on rapidity distributions are consistent with slight Feynman scaling violation at large rapidities and increasing inelasticities. (author)

1993-08-25

213

Effect of large supersymmetric phases on Higgs production  

CERN Document Server

If the soft supersymmetry (SUSY) breaking masses and couplings are complex and cancellations do take place in the SUSY induced contributions to the fermionic electric dipole moments, then the CP- violating soft phases can drastically modify much of the known phenomenological pattern of the minimal supersymmetric standard model. In particular, the squark loop content of the dominant Higgs production mechanism at the large hadron collider, the gluon-gluon fusion mode, could be responsible for large corrections to the known cross sections. (15 refs).

2000-01-01

214

Recent status of the development of intense ion beams  

Energy Technology Data Exchange (ETDEWEB)

Taking the development of large current, negative ion sources which is in progress aiming at nuclear fusion reactors and the development of high luminance ion sources planned as a part of the Omega Project as the examples, the technology for generating high power ion beams is explained. Both these projects are positioned at the limit of the present technology of high power ion beam application as their targeted beam power reaches several tens MW. Consequently, the requirement for the ion sources is severe, and in particular, the generation of the ion beams having large current density with good convergence is beyond all precedents. The application of high power ion sources has been realized as the neutral beam injectors for large tokamaks. Also the hydrogen negative ion source of large current and the electrostatic acceleration technology for negative ion beams have been developed. ...

1993-12-01

215

Segmentation and fragmentation of melt jets due to generation of large-scale structures. Observation in low subcooling conditions  

Energy Technology Data Exchange (ETDEWEB)

In order to clarify a mechanism of melt-jet breakup and fragmentation entirely different from the mechanism of stripping, a series of experiments were carried out by using molten tin jets of 100 grams with initial temperatures from 250degC to 900degC. Molten tin jets with a small kinematic viscosity and a large thermal diffusivity were used to observe breakup and fragmentation of melt jets enhanced thermally and hydrodynamically. We observed jet columns with second-stage large-scale structures generated by the coalescence of large-scale structures recognized in the field of fluid mechanics. At a greater depth, the segmentation of jet columns between second-stage large-scale structures and the fragmentation of the segmented jet columns were observed. It is reasonable to consider that the segmentation and the fragmentation of jet columns are caused by the boiling of water hydrodynamically entrained within ...

1999-07-01

216

Large-area metallic photonic lattices for military applications.  

Energy Technology Data Exchange (ETDEWEB)

In this project we developed photonic crystal modeling capability and fabrication technology that is scaleable to large area. An intelligent optimization code was developed to find the optimal structure for the desired spectral response. In terms of fabrication, an exhaustive survey of fabrication techniques that would meet the large area requirement was reduced to Deep X-ray Lithography (DXRL) and nano-imprint. Using DXRL, we fabricated a gold logpile photonic crystal in the <100> plane. For the nano-imprint technique, we fabricated a cubic array of gold squares. These two examples also represent two classes of metallic photonic crystal topologies, the connected network and cermet arrangement.

2007-11-01

217

Coverage and large scale anisotropies estimation methods for the Pierre Auger Observatory  

Energy Technology Data Exchange (ETDEWEB)

When searching for anisotropies in the arrival directions of Ultra High Energy Cosmic Rays, one must estimate the number of events expected in each direction of the sky in the case of a perfect isotropy. We present in this article a new method, developed for the Auger Observatory, based on a smooth estimate of the zenith angle distribution obtained from the data itself (which is essentially unchanged in the case of the presence of a large scale anisotropy pattern). We also study the sensitivity of several methods to detect large-scale anisotropies in the cosmic ray arrival direction distribution : Rayleigh analysis, dipole fitting and angular power spectrum estimation.

2005-07-01

218

An algorithm for scheduling a large pumped storage plant  

Energy Technology Data Exchange (ETDEWEB)

The Michigan Electric Coordination Center (MEPCC), operated by Consumers Power and Detroit Edison Companies, has the responsibility for scheduling the Ludington pumped storage plant. Ludington has an extremely large economic effect on the Consumers Power and Detroit Edison Companies' system due to its size (over 1800 MW net demonstrated generating capability). This paper presents a dynamic programming algorithm for scheduling large pumped storage plants and shows how this method can be coordinated with the commitment of the thermal units of the system.

1985-08-01

219

Treatment of Produced Waters Using a Surfactant Modified Zeolite/Vapor Phase Bioreactor System  

Energy Technology Data Exchange (ETDEWEB)

This report summarizes work performed on this project from October 2004 through March 2005. In previous work, a surfactant modified zeolite (SMZ) was shown to be an effective system for removing BTEX contaminants from produced water. Additional work on this project demonstrated that a compost-based biofilter could biodegrade the BTEX contaminants found in the SMZ regeneration waste gas stream. However, it was also determined that the BTEX concentrations in the waste gas stream varied significantly during the regeneration period and the initial BTEX concentrations were too high for the biofilter to handle effectively. A series of experiments were conducted to determine the feasibility of using a passive adsorption column placed upstream of the biofilter to attenuate the peak gas-phase VOC concentrations delivered to the biofilter during the SMZ regeneration process. In preparation for the field test of the SMZ/VPB treatment system in New Mexico, a pilot-scale SMZ system was also ...

2005-03-11

220

Radioactive targets for neutron-induced cross section measurements  

Science.gov (United States)

Measurements using radioactive targets are important for the determination of key reaction path ways associated with the synthesis of the elements in nuclear astrophysics (sprocess), advanced fuel cycle initiative (transmutation of radioactive waste), and stockpile stewardship. High precision capture cross-section measurements are needed to interpret observations, predict elemental or isotopical ratios, and unobserved abundances. There are two new detector systems that are presently being commissioned at Los Alamos National Laboratory for very precise measurements of (n,{gamma}) and (n,f) cross-sections using small quantities of radioactive samples. DANCE (Detector for Advanced Neutron-Capture Experiments), a 4 {pi} gamma array made up of 160 BaF{sub 2} detectors, is designed to measure neutron capture cross-sections of unstable nuclei in the low-energy range (thermal to {approx}500 keV). The high granularity and high detection efficiency of DANCE, combined with ...

2004-01-01

221

Aging of Pentaerythritol Tetranitrate (PETN)  

Science.gov (United States)

Pentaerythritol tetranitrate (PETN) is a relatively sensitive explosive used in many electroexplosive devices as well as in medicine. Of primary interest to LLNL is its use in items such as exploding bridgewire (EBW) detonators and exploding bridge foil initiators (EFI). In these devices the crystalline powder is pressed into a granular, low-density compact that can be initiated by an exploding wire or foil. The long-term stability of this pressed compact is of interest to weapon stockpile lifetime prediction studies. Key points about potential aging mechanisms can be summarized as follows: (1) There are a number of factors that can contribute to PETN instability. These include particle size, polymorphic phase transitions, crystal structure, impurities, moisture, occlusions, chemical incompatibility and biological (microorganism) action. of these factors the most important for long-term aging of high surface area powders used in detonators appears to be that of ...

2009-04-22

222

discs large in the Drosophila testis  

UK PubMed Central (United Kingdom)

Gamete development requires a coordinated soma-germ line interaction that ensures renewal and differentiation of germline and somatic stem cells. The physical contact between the germline and somatic...Full Text Available

2010-10-01

223

[SIAM conference on optimization  

Energy Technology Data Exchange (ETDEWEB)

Abstracts are presented of 63 papers on the following topics: large-scale optimization, interior-point methods, algorithms for optimization, problems in control, network optimization methods, and parallel algorithms for optimization problems.

1992-05-10

224

Wind Tunnel Flow Quality and Data Accuracy Requirements  

Science.gov (United States)

... tests, one often encounters, for instance, separated flows with large ... It is suspected that the flow-quality criteria given in AGARD Report No. ...

1982-11-01

225

Visible Earth: Haitian Deforestation - Visible Earth - NASA  

Science.gov (United States)

Jun 8, 2006 ... It also reflects the large amount of deforestation that has occurred on the Haitian side of the border. One can easily see from satellite imagery ...

226

Tumour affinity of [sup 203]Pb-chloride: comparison with [sup 67]Ga-citrate and [sup 201]Tl-chloride  

Energy Technology Data Exchange (ETDEWEB)

[sup 203]Pb-chloride is a promising imaging agent for tumour scanning because of the large retention value for tumour tissue and the small value for normal organs, but the large value for the kidneys and bone is a shortcoming. The retention value of [sup 203]Pb in tumour tissue is larger than that of [sup 201]Tl and smaller than that of [sup 67]Ga. The tumour/inflammatory lesion retention ratio for [sup 203]Pb is very large in comparison with those for [sup 67]Ga and [sup 201]Tl. [sup 203]Pb accumulates to a large extent in viable tumour tissue, and less in necrotic tumour tissue and in inflammatory lesion. (author).

1994-01-01

227

The role of large-scale, extratropical dynamics in climate change  

Energy Technology Data Exchange (ETDEWEB)

The climate modeling community has focused recently on improving our understanding of certain processes, such as cloud feedbacks and ocean circulation, that are deemed critical to climate-change prediction. Although attention to such processes is warranted, emphasis on these areas has diminished a general appreciation of the role played by the large-scale dynamics of the extratropical atmosphere. Lack of interest in extratropical dynamics may reflect the assumption that these dynamical processes are a non-problem as far as climate modeling is concerned, since general circulation models (GCMs) calculate motions on this scale from first principles. Nevertheless, serious shortcomings in our ability to understand and simulate large-scale dynamics exist. Partly due to a paucity of standard GCM diagnostic calculations of large-scale motions and their transports of heat, momentum, potential vorticity, and moisture, a comprehensive ...

1994-02-01

228

The Expanded Large Scale Gap Test  

Science.gov (United States)

... an Page 15. NSWC TR 86-32 exploding bridgewire detonator containing PETN rather, than a pri'mary explosive. However ...

1987-03-01

229

The Autophagy Connection  

UK PubMed Central (United Kingdom)

For a process intimately connected to an immense range of physiological processes, the molecular understanding of macroautophagy remains far from complete. Recent large-scale studies, including...Full Text Available

2010-07-20

230

Technology for Large Space Systems - NASA Technical Reports Server  

Science.gov (United States)

(AIM PAPER 81-1628). Three different examples will be given to illustrate how a ...... Power System (PS), and a Science Applications and Space Platform ...

231

Spread dynamics of invasive species  

UK PubMed Central (United Kingdom)

Species invasions are a principal component of global change, causing large losses in biodiversity as well as economic damage. Invasion theory attempts to understand and predict invasion success and...Full Text Available

2006-01-10

232

Spatial and Temporal Variability of Column Integrated Aerosol - NASA  

Science.gov (United States)

the southern Arabian Gulf region left its signature on the heterogeneous aerosol .... Arabian Gulf region, since large differences in ? may be caused by ...

233

Solution of large-scale sparse least squares problems using auxiliary storage  

Energy Technology Data Exchange (ETDEWEB)

Very large sparse linear least-squares problems arise in a variety of applications, such as geodetic network adjustments, photogrammetry, earthquake studies, and certain types of finite element analysis. Many of these problems are so large that it is impossible to solve them without using auxiliary storage devices. Some problems are so massive that the storage needed for their solution exceeds the virtual address space of the largest machines. A method for solving such problems on a typical (large) computer is described, and the results of some experiments illustrating the effectiveness of this approach are provided. The method includes an automatic partitioning scheme that is essential to the efficient management of the data on auxiliary files. 8 figures, 2 tables

1980-08-01

234

Solid Waste & Financial Assistance Program  

Science.gov (United States)

This program deals with solid waste disposal with topics/services covering: Reusable Building Materials and Large Household Items Exchange, Beneficial Use Determination, Biosolids, Certification, Compost Facil...

235

Size Effects in Impact Damage of Composite Sandwich Panels Alan ...  

Science.gov (United States)

Wade. Jackson. - Army. VTD at NASA. Langley. ABSTRACT. Panel size has a large effect on the impact response and resultant damage level of honeycomb sandwich ...

236

Silicon solar cell assembly  

Science.gov (United States)

A silicon solar cell assembly comprising a large, thin silicon solar cell bonded to a metal mount for use when there exists a mismatch in the thermal expansivities of the device and the mount.

1979-01-01

237

Removing tachyons by compactification  

Energy Technology Data Exchange (ETDEWEB)

It is shown that tachyons in the recently discovered ten-dimensional non-supersymmetric heterotic string models can be removed by compactifying on tori in the presence of large Wilson lines.

1987-01-29

238

Removing tachyons by compactification  

International Nuclear Information System (INIS)

It is shown that tachyons in the recently discovered ten-dimensional non-supersymmetric heterotic string models can be removed by compactifying on tori in the presence of large Wilson lines. (orig.).

239

Refilling Intracellular Calcium Stores  

UK PubMed Central (United Kingdom)

Within the cardiac cell, the movements of calcium ions are tightly regulated by a number of regulatory proteins including pumps, and channels. The sarcoplasmic reticulum (SR) is in large part...Full Text Available

2010-01-01

240

Psychological Resilience and Neurocognitive Performance in a Traumatized Community Sample  

UK PubMed Central (United Kingdom)

BackgroundWhether psychological resilience correlates with neurocognitive performance is largely unknown. Therefore, we assessed association between neurocognitive...Full Text Available

2010-08-01

241

Proteinortho: Detection of (Co-)orthologs in large-scale analysis  

UK PubMed Central (United Kingdom)

BackgroundOrthology analysis is an important part of data analysis in many areas of bioinformatics such as comparative genomics and molecular phylogenetics. The ever-increasing flood...Full Text Available

242

Protein misfolding disorders and macroautophagy  

UK PubMed Central (United Kingdom)

A large group of diseases, termed protein misfolding disorders, share the common feature of the accumulation of misfolded proteins. The possibility of a common mechanism underlying either the pathogenesis...Full Text Available

2011-04-01

243

Prevention among immigrants: the example of Germany  

UK PubMed Central (United Kingdom)

BackgroundA large and increasing part of the European population has a history of migration. Germany, for example, is home to about 15 million people with migrant background, which...Full Text Available

244

Orbital ordering, ferroelasticity, and the large pressure induced volume collapse in PbCrO3  

CERN Document Server

We report a new tetragonal ground-state for perovskite-structured PbCrO3 from DFT+U calculations, and explain its anomalously large volume. The new structure is stabilized due to orbital ordering of Cr-d in the presence of a large tetragonal crystal field, mainly due to off-centering of the Pb atom. At higher pressures (smaller volumes) there is a first-order transition to a cubic phase where the Cr-d orbitals are orbitally liquid. This phase-transition is accompanied by a ~11.5% volume collapse, one of the largest known for transition-metal oxides. The large ferroelasticity and its strong coupling to the orbital degrees of freedom could be exploited to form potentially useful magnetostrictive materials

2011-01-01

245

Operating Characteristics of a Three-Piece-Inner-Ring Large-Bore ...  

Science.gov (United States)

roller bearing with a one-piece inner ring. The lubricant experimental data on high-speed roller .... roller bearing. The outer ring of the test bearing was ...

246

Open cholecystectomy. A contemporary analysis of 42,474 patients.  

UK PubMed Central (United Kingdom)

OBJECTIVE: This study evaluated, in a large, heterogeneous population, the outcome of open cholecystectomy as it is currently practiced. SUMMARY BACKGROUND AND DATA: Although cholecystectomy has been...Full Text Available

1993-08-01

247

Ngo-2s644 - NASA Technical Report Server (NTRS)  

Science.gov (United States)

a large number of polycrystalline materials, has the fot_ of the. Manson-Coffin- Basquin equation, wherein the exponents of the two power law terms are given ...

248

Mitochondrial Dysfunction: The Road to Alpha-Synuclein Oligomerization in PD  

UK PubMed Central (United Kingdom)

While the etiology of Parkinson's disease remains largely elusive, there is accumulating evidence suggesting that mitochondrial dysfunction occurs prior to the onset of symptoms in Parkinson's disease....Full Text Available

249

Mining in Russia. Alliance of science and production  

Energy Technology Data Exchange (ETDEWEB)

The author indicates the research which will be done as part of Programme Sibir, a large-scale programme for the development of the eastern USSR. The research includes the liquefaction of brown coal, and new methods of prospecting.

1982-01-01

250

Managing Cancer Pain  

UK PubMed Central (United Kingdom)

Despite the existence of effective analgesic drugs, many cancer patients live and die with ineffective pain control. The control of cancer pain is largely achievable with the appropriate use of available...Full Text Available

1984-02-01

251

Light Weight Composite Mirrors for Science Instruments  

Science.gov (United States)

Light Weight Composite Mirrors for Science Instruments. Composite Optics, Inc. San Diego, CA. INNOVATION. Light weight, large aperture reflectors of graphite ...

252

Large Eddy Simulation of Supersonic Turbulent Flow in ...  

Science.gov (United States)

... AGARD AR-319, Volume 2. Knight, D., Zhou ... a Turbulent Boundary Layer in a Supersonic Flow. ... of Development of Separated Flows in Compression ...

2001-08-01

253

Large Eddy Simulation for Heat Transfer Prediction in a Gas ...  

Science.gov (United States)

... turbine blade heat-transfer and study the heat-transfer augmentation in idealized geometry and its ... responsible for heat transfer augmentation. ...

2007-03-30

254

Human-modified ecosystems and future evolution  

UK PubMed Central (United Kingdom)

Our global impact is finally receiving the scientific attention it deserves. The outcome will largely determine the future course of evolution. Human-modified ecosystems are shaped by our activities...Full Text Available

2001-05-08

255

Human viral gastroenteritis.  

UK PubMed Central (United Kingdom)

During the last 15 years, several different groups of fastidious viruses that are responsible for a large proportion of acute viral gastroenteritis cases have been discovered by the electron microscopic...Full Text Available

1989-01-01

257

Heat shock proteins as emerging therapeutic targets  

UK PubMed Central (United Kingdom)

Chaperones (stress proteins) are essential proteins to help the formation and maintenance of the proper conformation of other proteins and to promote cell survival after a large variety of environmental...Full Text Available

2005-11-01

259

General Disclaimer One or more of the Following Statements may ...  

Science.gov (United States)

Oberpfaffenhofen, Pedel"al aepublic of Gel1lany. A large number of European scientists have provided ex~eri- ments that will be cooducted in the Material ...

260

Francisella Tularensis Metabolism and its Relation to Virulence  

UK PubMed Central (United Kingdom)

Francisella tularensis is a Gram-negative bacterium capable of causing the zoonotic disease tularaemia in a large number of mammalian species and in arthropods. F. tularensis...Full Text Available

261

Fluid Transport Phenomena in Ocular Epithelia  

UK PubMed Central (United Kingdom)

This article discusses three largely unrecognized aspects related to fluid movement in ocular tissues; namely, a) the dynamic changes in water permeability observed in corneal and conjunctival...Full Text Available

2008-03-01

263

Enhancing AIS to Improve Whale-Ship Collision Avoidance ...  

Science.gov (United States)

... 2008. Characterizing the relative contributions of large vessels to total ocean noise fields: a case study using the Gerry E. Studds Stellwagen Bank ...

2010-06-01

264

EFFECTS OF AMBIENT NOISE ON THE WHISTLES OF INDO-PACIFIC BOTTLENOSE DOLPHIN POPULATIONS  

Science.gov (United States)

... Characterizing the Relative Contributions of Large Vessels to Total Ocean Noise Fields: A Case Study Using the Gerry E. ... ...

265

Deforestation in the Tropics  

Science.gov (United States)

Government policies that encourage exploitation--in particular excessive logging and clearing for ranches and farms--are largely to blame for the accelerating destruction of tropical forests. This paper surveys the problem in detail and briefly recommends potential solutions.

1990-04-01

266

Correlated Bivariate Continuous and Binary Outcomes: Issues and Applications  

UK PubMed Central (United Kingdom)

SUMMARYIncreasingly multiple outcomes are collected in order to characterize treatment effectiveness or to evaluate the impact of large policy initiatives. Often the multiple...Full Text Available

2009-06-15

267

Correction factors determination in large samples gamma assay using its own multi-gamma lines spectrum  

Energy Technology Data Exchange (ETDEWEB)

An easy and simple method for gamma assay of large multi-gamma lines samples was introduced in this work. This method performs the assay using point source calibration. The correction factors for volume and self-attenuation are experimentally deduced from the spectra of different thicknesses samples utilizing the following two simple well known facts: large and small samples of the same homogenous material have identical specific activities; the self-attenuation of gamma line decreases as its energy increases. The method was successfully applied to naturally occurring radioactive material (NORM) large samples. This method does not require complicated mathematical procedures. Neither sample matrix data nor detector unit composition is needed.

2009-10-15

268

Correction factors determination in large samples gamma assay using its own multi-gamma lines spectrum  

International Nuclear Information System (INIS)

An easy and simple method for gamma assay of large multi-gamma lines samples was introduced in this work. This method performs the assay using point source calibration. The correction factors for volume and self-attenuation are experimentally deduced from the spectra of different thicknesses samples utilizing the following two simple well known facts: large and small samples of the same homogenous material have identical specific activities; the self-attenuation of gamma line decreases as its energy increases. The method was successfully applied to naturally occurring radioactive material (NORM) large samples. This method does not require complicated mathematical procedures. Neither sample matrix data nor detector unit composition is needed.

2009-10-01

269

Correction factors determination in large samples gamma assay using its own multi gamma lines spectrum  

International Nuclear Information System (INIS)

An easy and simple method for gamma assay of large multi gamma lines samples was introduced in this work. This method performs the assay using point source calibration. The correction factors for volume and self-attenuation are experimentally deduced from the spectra of different thicknesses samples utilizing the following tow simple well known facts: Large and small samples of the same homogenous material have identical activities; the self attenuation of gamma line decreases as its energy increases. The method was successfully applied to NORM (Naturally Occurring Radioactive Material) large samples. This method doesn't require complicated mathematical procedures. Neither sample matrix data nor detector unit composition is needed. (author)

270

Conjugate Heat Transfer Predictions of a Combustor ...  

Science.gov (United States)

... To maximise heat transfer rates, many heatshield designs make use of heat transfer augmentation devices such as large numbers of pin-fin ...

2003-03-01

271

Compressing DNA sequence databases with coil  

UK PubMed Central (United Kingdom)

BackgroundPublicly available DNA sequence databases such as GenBank are large, and are growing at an exponential rate. The sheer volume of data being dealt with presents serious...Full Text Available

272

Comparison of energy flows in deep inelastic scattering events with and without a large rapidity gap  

Energy Technology Data Exchange (ETDEWEB)

Energy flows in deep inelastic electron-proton scattering are investigated at a centre-of-mass energy of 296 GeV for the range Q{sup 2}{>=}10 GeV{sup 2} using the ZEUS detector. A comparison is made between events with and without a large rapidity gap between the hadronic system and the proton direction. The energy flows, corrected for detector acceptance and resolution, are shown for these two classes of events in both the HERA laboratory frame and the Breit frame. From the differences in the shapes of these energy flows we conclude that QCD radiation is suppressed in the large-rapidity-gap events compared to the events without a large rapidity gap. (orig.)

1994-07-01

273

Chronic kidney disease in children: the global perspective  

UK PubMed Central (United Kingdom)

In contrast to the increasing availability of information pertaining to the care of children with chronic kidney disease (CKD) from large-scale observational and interventional studies, epidemiological...Full Text Available

2007-12-01

274

Benefits of Using the Photosimulation Laboratory Environment ...  

Science.gov (United States)

... with the ability to capture imagery in raw 24-bit format, combined with large memory storage devices enable high resolution imagery to be captured ...

2002-08-01

275

Age determination of large live trees with inner cavities: radiocarbon dating of Platland tree, a giant African baobab  

British Library Electronic Table of Contents (United Kingdom)

? Introduction For large trees without a continuous sequence of growth rings in their trunk, such as the African baobab (Adansonia digitata L.), the only accurate method for age determination is radiocarbon dating. As of today, this method was limited to dating samples collected from the remains of dead specimens. ? Methods Our research extends significantly the dating of such trees to large live specimens with inner cavities. The new approach is based on collecting samples from the cavities and their subsequent radiocarbon dating. ? Results The giant two-stemmed Platland tree, also known as Sunland baobab, was investigated by using this new approach. AMS radiocarbon dates of the oldest sample segments originating from the two inner cavities indicate that the large stem I (364.5?m3) is 750...

2011-01-01

276

A framework for evolutionary systems biology  

UK PubMed Central (United Kingdom)

BackgroundMany difficult problems in evolutionary genomics are related to mutations that have weak effects on fitness, as the consequences of mutations with large effects are often...Full Text Available

277

Use of boron waste as an additive in red bricks  

International Nuclear Information System (INIS)

In boron mining and processing operations, large amounts of clay containing tailings have to be discarded. Being rich in boron, the tailings do not only cause economical loss but also pose serious environmental problems. Large areas have to be allocated for waste disposal. In order to alleviate this problem, the possibility of using clayey tailings from a borax concentrator in red brick manufacturing was investigated. Up to 30% by weight tailings addition was found to improve the brick quality.

278

Transient enhanced diffusion of oxygen in Fe mediated by large electronic excitation  

International Nuclear Information System (INIS)

Contrary to the electronic excitation induced phenomena of desorption and sputtering, we observed incorporation of oxygen in a thin Fe film during its irradiation with swift heavy ions. It is observed that the adsorbed oxygen diffuses in to the Fe film. The incorporation of oxygen and its diffusion in the bulk of the film is a manifestation of extremely large electronic energy deposition by the incident ions. It is shown that the experimentally observed high diffusivity of oxygen in Fe during irradiation is due to the existence of transient melt phase of Fe.

2003-10-15

279

The two-dimensional Stefan problem with slightly varying heat flux  

Science.gov (United States)

The authors solve the two-dimensional stefan problem of solidification in a half-space, where the heat flux at the wall is a slightly varying function of positioning along the wall, by means of a large Stefan number approximation (which turns out to be equivalent to a small time solution), and then by means of the Heat Balance Integral Method, which is valid for all time, and which agrees with the large Stefan number solution for small times. A representative solution is given for a particular form of the heat flux perturbation.

1995-09-01

280

The environmental impacts of a large gas-fired combined cycle power station  

Energy Technology Data Exchange (ETDEWEB)

The paper discusses the potential environmental impacts associated with the operation of a large, say 350 MWe, gas-fired combined cycle power station. It concludes that if appropriate control methods are introduced at the design stage of the plant, environmental impacts are minimal and can be considered acceptable. (author).

1991-11-01

281

Selective Expression in Carotid Body Type I Cells of a Single Splice Variant of the Large Conductance Calcium- and Voltage-activated Potassium Channel Confers Regulation by AMP-activated Protein Kinase*  

UK PubMed Central (United Kingdom)

Inhibition of large conductance calcium-activated potassium (BKCa) channels mediates, in part, oxygen sensing by carotid body type I cells. However, BKCa channels remain active...Full Text Available

2011-04-08

282

Quantum chaos in the mixmaster universe  

Energy Technology Data Exchange (ETDEWEB)

A Monte Carlo simulation of the vacuum Bianchi type-IX (mixmaster) cosmology yields a significant correlation between large universe volume and high anisotropy. An analog of the model's chaotic classical behavior is seen in the break up of the universe wave function at large volume into fingers in the corners of the minisuperspace anisotropy potential.

1989-04-15

283

Problems of the radiometric level measurement in large bins  

Energy Technology Data Exchange (ETDEWEB)

After a brief survey of the known level measurement methods the particularities of the radiometric measurement of the still utilisable residual volume of a bulk material in a large bin are discussed. At constant angle of repose the measurement in a suitably positioned plane of measurement suffices, at variable angle of repose two planes of measurement are required. The probable working ranges for a 1300-t lime bin are estimated.

1984-01-01

284

Performance of large LWR system codes in calculating the steam-generator heat-transfer behavior  

Energy Technology Data Exchange (ETDEWEB)

This paper presents a series of modeling experiences and problems in simulating the thermal-hydraulic behavior of large PWR steam generators using the RELAP4 and RELAP5 computer codes. Sensitivity studies investigating the heat transfer characteristics of both once-through and U-tube steam generators are discussed. Suggestions and recommendations are given for effective use and potential future improvements of these codes.

1982-01-01

285

Numerical error analysis of direct integration method  

Energy Technology Data Exchange (ETDEWEB)

Numerical errors of PALLAS calculation due to spatial mesh sizes are examined for a typical deep penetration shielding problem of isotropic incident fission neutrons penetrating a 200-cm-thick water slab. The exponential approximation for the source spatial distribution to solve the transport equation based on the direct integration method is verified to be effective for radiation transport in attenuating medium, while the linear approximation employed in the old PALLAS code is found to produce large errors for calculations with large mesh sizes.

1986-01-01

286

NPM-ALK and the JunB transcription factor regulate the expression of cytotoxic molecules in ALK-positive, anaplastic large cell lymphoma  

UK PubMed Central (United Kingdom)

Anaplastic lymphoma kinase-positive, anaplastic large cell lymphoma (ALK+ ALCL) is an aggressive non-Hodgkin lymphoma of T/null immunophenotype that is most prevalent in children and young adults. The...Full Text Available

2011-02-15

287

Management considerations of the large primary-to-secondary leakage accidents  

Energy Technology Data Exchange (ETDEWEB)

The management procedure of a large PRISE (Primary-to-Secondary) leakage accident at Loviisa nuclear power plant taking into account the plant modifications which are expected to be realized during 1995-96 is described. The management procedure has been validated by performing thermal hydraulic analyses with the computer code RELAP5/MOD3 and the results from these analyses are also shortly discussed. (4 refs., 6 figs., 1 tab.).

1993-12-31

288

Large-Scale Computations Leading to a First-Principles Approach to Nuclear Structure  

Energy Technology Data Exchange (ETDEWEB)

We report on large-scale applications of the ab initio, no-core shell model with the primary goal of achieving an accurate description of nuclear structure from the fundamental inter-nucleon interactions. In particular, we show that realistic two-nucleon interactions are inadequate to describe the low-lying structure of {sup 10}B, and that realistic three-nucleon interactions are essential.

2003-08-18

289

Large T1 oligonucleotides of Moloney leukemia virus missing in an env gene recombinant, HIX, are present on an intracellular 21S Moloney viral RNA species.  

UK PubMed Central (United Kingdom)

HIX, a recombinant derived from Moloney leukemia virus, has an envelope glycoprotein different from that of the Moloney virus. HIX and Moloney viruses share the majority of the large T1 oligonucleotides...Full Text Available

1978-06-01

290

Flow control with variable inflow as an alternative to conventional nozzle group control - automatic control of large capacity steam turbines  

International Nuclear Information System (INIS)

In the case of large capacity steam turbines the conventional nozzle group control is, for mechanical and thermodynamic reasons, diminishing more and more in importance in favour of variable pressure control. A design for constant-pressure operation as an alternative to nozzle group control is described; this demonstrates a series of important advantages compared with the latter. (orig.).

291

Factors affecting the tensile ductility of a metastable beta titanium alloy  

International Nuclear Information System (INIS)

The ductility of extruded heavy-section Ti-base--Mo--V--Fe--Al alloy was studied. Metallographic evidence for the large effect of grain size on ductility is presented. Fracture was found to occur in large-grain material after less deformation than in smaller grain size specimens.

292

Document Clustering with K-tree  

CERN Document Server

This paper describes the approach taken to the XML Mining track at INEX 2008 by a group at the Queensland University of Technology. We introduce the K-tree clustering algorithm in an Information Retrieval context by adapting it for document clustering. Many large scale problems exist in document clustering. K-tree scales well with large inputs due to its low complexity. It offers promising results both in terms of efficiency and quality. Document classification was completed using Support Vector Machines.

2010-01-01

293

Computer modeling of two-phase flow  

Science.gov (United States)

The accelerating flow of a lighter continuous phase through a heavier one is considered. Small nonuniformities grow into large ones due to the Rayleigh-Taylor instability. An experiment exemplifying the large bubble formation due to Rayleigh-Taylor instability was performed and simulated using the PHOENICS 84 computer code. The same numerical procedure was applied to the two-phase flow in a gun barrel. It shows that the acceleration provided by the movement of the projectile can cause initial nonuniformities to grow with time.

1986-10-01

294

Automatic computation of three-loop two-point functions in large momentum expansion  

International Nuclear Information System (INIS)

We discuss the calculation of two-point three-loop functions with an arbitrary number of massive propagators and one large external momentum. The relevant subdiagrams are generated automatically. The resulting massless two-point integrals and massive tadpoles are transformed on-line to FORM-expressions ready to be used by existing FORM packages which calculate them analytically. As an example we compute the quartic mass corrections to the photon polarization function. (orig.).

295

Analysis of low-level computer vision algorithms for implementation on a very large scale integrated (VLSI) processor array  

Energy Technology Data Exchange (ETDEWEB)

In a recent paper, Lowry (1981) described an architecture for a computer vision rectangular processor array that is suitable for VLSI implementation. In this paper the authors review that architecture, discuss extensions to it and present results of an array simulator applied to vision algorithms. They also present an algorithm for re-routing an array with bad processors into a working subset of the array, making it feasible to implement a large array on one wafer-sized chip. 7 references.

1982-01-01

296

A two-frequency Wiggler for a better control of a free-electron-laser dynamics  

Energy Technology Data Exchange (ETDEWEB)

In the paper is studied the physics of a free electron laser (FEL) based on a two-frequency undulator (TFU) which induces large non linear effects, especially on the spectral dynamics. These effects are analyzed in an extended formalism where the spontaneous emission, the low-gain regime and the strong-field saturation regime are studied. Numerical simulations show that the optimized TFU generates a laser field having both a large extraction efficiency and a narrow spectrum.

1991-12-31

297

A large-acceptance Bragg curve spectrometer with a longitudinal electric field and a segmented anode  

Energy Technology Data Exchange (ETDEWEB)

A large-acceptance Bragg curve spectrometer with a longitudinal electron collection field and a segmented anode has been constructed and tested. The effects on the charge resolution of the entrance angle and entrance position of the incident particle have been studied. Simulations have been done in order to isolate the contribution to the overall detector performance of the signal-shaping electronics from that of the intrinsic design of the detector. ((orig.))

1994-07-15

298

Signal Processing in Large Systems: a New Paradigm  

CERN Document Server

For a long time, signal processing applications, and most particularly detection and parameter estimation methods, have relied on the limiting behaviour of test statistics and estimators, as the number n of observations of a population grows large comparatively to the population size N, i.e. n>>N. Modern technological and societal advances now demand the study of sometimes extremely large populations, while simultaneously requiring fast signal processing due to accelerated system dynamics; this results in not-so-large practical ratios n/N, sometimes even smaller than one. A disruptive change in classical signal processing methods has therefore been initiated in the past ten years, mostly spurred by the field of large dimensional random matrix theory. The early literature in random matrix theory for signal processing applications is however scarce and highly technical. This tutorial proposes an ...

2011-01-01

299

Large temperature differential thermal storage system. Its design and evaluation  

Energy Technology Data Exchange (ETDEWEB)

A large temperature differential (10K) thermal storage system in a small (4400 m{sup 2}) 8-storey office building is discussed and the monitoring results are analyzed in comparison with computer simulations. Requirements were a comfortable indoor environment and system cost effectiveness. Out of four potential system concepts, the Large Temperature Differential System was chosen. It comprises a flat-type thermal stratification heat storage tank in the under floor pit of the building as the heat source for a variable flow heat pump chiller. The heat sink is a set of serially connected air handling and fan coil units. The tank`s capacity is sized for one day operation and is made as large as possible to shift the electricity demand to night time. To avoid a large size and high cost, the water temperature differential was enlarged. The role of Tokyo Electric Power Company (TEPCO) was to develop the chiller ...

1996-07-01

300

The EKC for SO2: Does firm size matter?  

British Library Electronic Table of Contents (United Kingdom)

The environmental Kuznets curve hypothesis (EKC) predicts an inverse U-shaped relationship between environmental pollution and per capita income. The literature with respect to the EKC is vast but far from conclusive. This paper adds firm size to the standard EKC reduced form regression and analyses whether firm size matters once income and composition are controlled for. Results suggest that large firm countries are initially associated with higher levels of environmental damage. However, as economies develop, large firm countries find it easier to adopt more stringent environmental legislation. Once environmental damage starts to decrease, the decrease is much larger in large firm countries.

2006-01-01

301

Strings and QCD  

Energy Technology Data Exchange (ETDEWEB)

We point out that the occurrence of a large-distance ''Coulomb'' term in the static quark-antiquark potential is related to tachyons in the underlying string model. Thus, the tachyon contents determine the coefficient of the ''Coulomb'' term. For a scalar string, one has Luescher's result -(d-2) /24R, for a Neveu-Schwarz string one obtains -(d-2) /16R, whereas for the Ramond string (and strings without tachyons) the ''Coulomb'' term vanishes. Monte Carlo data for QCD prefers a ''Coulomb'' term. This is not inconsistent with the tachyonic origin of this term, since the large-distance behaviour of string models is consistent even with tachyons. Also, critical dimensions are not necessary at large distances.

1985-10-03

302

Species Inequality in Scientific Study  

British Library Electronic Table of Contents (United Kingdom)

Abstract: Some conservationists argue for a focused effort to protect the most critically endangered species, and others suggest a large-scale endeavor to safeguard common species across large areas. Similar arguments are applicable to the distribution of scientific effort among species. Should conservation scientists focus research efforts on threatened species, common species, or do all species deserve equal attention? We assessed the scientific equity among 1909 mammals, birds, reptiles, and amphibians of southern Africa by relating the number of papers written about each species to their status on the International Union for Conservation of Nature Red List. Threatened large mammals and reptiles had more papers written about them than their nonthreatened counterparts, whereas threatened...

2010-01-01

303

Simulating Large-scale Structure  

CERN Document Server

After two decades of direct dynamical simulation of large-scale structure in the universe, it is safe to say the subject is now mature. Still, there are parts of the problem that are less well developed than others. In general, the collisionless dynamics of the dark matter component is better understood than the collisional gas dynamics of the baryonic component. In situations where the gas dynamics is relatively simple, such as the Lyman-$\\alpha$ forest and the intracluster medium in X-ray clusters, our ability to reproduce observational data has evolved rapidly, and the interpretive and predictive power of such experiments should now be taken seriously. A comparison of twelve gas dynamic codes to the problem of forming a single X-ray cluster shows that numerical inaccuracies are modest (typically below ten percent), leaving missing physics as the main source for large systematic differences between theory and observation. Galaxy formation, ...

1998-01-01

304

Self-similarity and power-like tails in nonconservative kinetic models  

CERN Document Server

In this paper, we discuss the large--time behavior of solution of a simple kinetic model of Boltzmann--Maxwell type, such that the temperature is time decreasing and/or time increasing. We show that, under the combined effects of the nonlinearity and of the time--monotonicity of the temperature, the kinetic model has non trivial quasi-stationary states with power law tails. In order to do this we consider a suitable asymptotic limit of the model yielding a Fokker-Planck equation for the distribution. The same idea is applied to investigate the large-time behavior of an elementary kinetic model of economy involving both exchanges between agents and increasing and/or decreasing of the mean wealth. In this last case, the large-time behavior of the solution shows a Pareto power law tail. Numerical results confirm the previous analysis.

2010-01-01

305

Photoluminescence in large fluence radiation irradiated space silicon solar cells  

Energy Technology Data Exchange (ETDEWEB)

Photoluminescence spectroscopy measurements were carried out for silicon 50{mu}m BSFR space solar cells irradiated with 1MeV electrons with a fluence exceeding 1 x 10{sup 16} e/cm{sup 2} and 10MeV protons with a fluence exceeding 1 x 10{sup 13} p/cm{sup 2}. The results were compared with the previous result performed in a relative low fluence region, and the radiation-induced defects which cause anomalous degradation of the cell performance in such large fluence regions were discussed. As far as we know, this is the first report which presents the PL measurement results at 4.2K of the large fluence radiation irradiated silicon solar cells. (author)

1997-03-01

306

On the two-loop Yukawa corrections to the MSSM Higgs boson masses at large tan(beta)  

CERN Document Server

We complete the effective potential calculation of the two-loop, top/bottom Yukawa corrections to the Higgs boson masses in the Minimal Supersymmetric Standard Model, by computing the O(at^2 + at*ab + ab^2) contributions for arbitrary values of the bottom Yukawa coupling. We also compute the corrections to the minimization conditions of the effective potential at the same perturbative order. Our results extend the existing O(at^2) calculation, and are relevant in regions of the parameter space corresponding to tan(beta) >> 1. We extend to the Yukawa corrections a convenient renormalization scheme, previously proposed for the O(ab*as) corrections, that avoids unphysically large threshold effects associated with the bottom mass and absorbs the bulk of the corrections into the one-loop expression. For large values of tan(beta), the new contributions can account for a variation of several GeV in the lightest Higgs boson mass.

2003-01-01

307

New implementation of a shear-force microscope suitable to study topographical features over wide areas  

International Nuclear Information System (INIS)

A new implementation of a shear-force microscope is described that uses a shear-force detection system to perform topographical imaging of large areas (#approx#1x1 mm"2). This implementation finds very interesting application in the study of archeological or artistic samples. Three dc motors are used to move a sample during a scan, allowing the probe tip to follow the surface and to face height differences of several tens of micrometers. This large-area topographical imaging mode exploits new subroutines that were added to the existing homemade software; these subroutines were created in Microsoft VISUAL BASIC 6.0 programming language. With this new feature our shear-force microscope can be used to study topographical details over large areas of archaeological samples in a nondestructive way. We show results detecting worn reliefs over a coin.

2006-09-01

308

Magnetocaloric and magnetoresistance studies of GdPd{sub 2}Si  

Energy Technology Data Exchange (ETDEWEB)

The compound GdPd{sub 2}Si, which is reported to order antiferromagnetically at 13 K, has been investigated by heat capacity and electrical resistivity measurement in the presence of external magnetic fields. In contrast to an earlier report, the zero-field heat capacity and resistivity data indicate two magnetic transitions at 13 and 17 K. The external magnetic field substantially influences the resistivity and heat capacity of the compound around the magnetic ordering temperature. The magnetocaloric effect, which is calculated from in-field heat capacity data, is quite large around the magnetic transition temperature. The magnetoresistance is also large near the magnetic ordering temperature. The metamagnetic transition is observed for 10 kOe magnetic field both in magnetocaloric and in magnetoresistance data. The metamagnetic transition strongly influences the magnetocaloric effect and magnetoresistance, which is large ...

2001-01-22

309

Magnetocaloric and magnetoresistance studies of GdPd_2Si  

International Nuclear Information System (INIS)

The compound GdPd_2Si, which is reported to order antiferromagnetically at 13 K, has been investigated by heat capacity and electrical resistivity measurement in the presence of external magnetic fields. In contrast to an earlier report, the zero-field heat capacity and resistivity data indicate two magnetic transitions at 13 and 17 K. The external magnetic field substantially influences the resistivity and heat capacity of the compound around the magnetic ordering temperature. The magnetocaloric effect, which is calculated from in-field heat capacity data, is quite large around the magnetic transition temperature. The magnetoresistance is also large near the magnetic ordering temperature. The metamagnetic transition is observed for 10 kOe magnetic field both in magnetocaloric and in magnetoresistance data. The metamagnetic transition strongly influences the magnetocaloric effect and magnetoresistance, which is large in ...

2001-01-22

310

Large specific absorption rates in the magnetic hyperthermia properties of metallic iron nanocubes  

CERN Document Server

We report on the magnetic hyperthermia properties of chemically synthesized ferromagnetic 11 and 16 nm Fe(0) nanoparticles of cubic shape displaying the saturation magnetization of bulk iron. The specific absorption rate measured on 16 nm nanocubes is 1690+-160 W/g at 300 kHz and 66 mT. This corresponds to specific losses-per-cycle of 5.6 mJ/g, largely exceeding the ones reported in other systems. A way to quantify the degree of optimization of any system with respect to hyperthermia applications is proposed. Applied here, this method shows that our nanoparticles are not fully optimized, probably due to the strong influence of magnetic interactions on their magnetic response. Once protected from oxidation and further optimized, such nano-objects could constitute efficient magnetic cores for biomedical applications requiring very large heating power.

2010-01-01

311

Large (≥2cm) non-hypervascular nodules depicted on MRI in the cirrhotic liver: fate and implications  

British Library Electronic Table of Contents (United Kingdom)

Aim To determine the fate and clinical implication of large (?2cm), non-hypervascular nodules depicted on magnetic resonance imaging (MRI) in the cirrhotic liver. Materials and methods In 21 patients with cirrhosis (14 hepatitis B, two ethanol abuse, four cryptogenic, one Wilson's disease), 25 large (?2cm in the longest dimension) non-hypervascular nodules were identified on dynamic MRI. The implications for diagnosis of the initial size, contour, and signal characteristics on MRI in addition to patients' age and cause of cirrhosis were assessed in our analysis. Results Twelve (75%) out of 16 lesions were malignant or potentially-malignant from 14 hepatitis B patients, while seven (78%) of the nine lesions from other patients were benign (p=0.016). The mean age of the patients who ha...

2008-01-01

312

Idealized gas turbine combustor for performance research and validation of large eddy simulations.  

Science.gov (United States)

This paper details the design of a premixed, swirl-stabilized combustor that was designed and built for the express purpose of obtaining validation-quality data for the development of large eddy simulations (LES) of gas turbine combustors. The combustor features nonambiguous boundary conditions, a geometrically simple design that retains the essential fluid dynamics and thermochemical processes that occur in actual gas turbine combustors, and unrestrictive access for laser and optical diagnostic measurements. After discussing the design detail, a preliminary investigation of the performance and operating envelope of the combustor is presented. With the combustor operating on premixed methane/air, both the equivalence ratio and the inlet velocity were systematically varied and the flame structure was recorded via digital photography. Interesting lean flame blowout and resonance characteristics were observed. In addition, the combustor exhibited a ...

2007-03-01

313

High-speed, low-altitude payload delivery using a single large ribbon parachute  

Energy Technology Data Exchange (ETDEWEB)

A 46.3-ft-dia 20-degree conical ribbon parachute has been designed to retard a 2200-lb payload delivered at speeds up to 800 KCAS and at altitudes as low as 150 feet above ground level. The parachute uses both Kevlar and nylon materials, some of which were developed specifically for this parachute. The canopy design incorporates a patented construction geometry to minimize stress concentrations. A cluster of three 3.8-ft-dia ribbon parachutes is used to deploy the main parachute in the presence of severe aircraft flow field effects and large payload angles of attack. The results of over 30 full-scale flight tests indicate that fundamental limitations imposed by the dynamics of the air masses inside and behind the canopy determine the ultimate performance of a single large parachute when it is used at a release altitude of 150 ft.

1983-01-01

314

Generation and mobility of radon in soil. Technical report  

Energy Technology Data Exchange (ETDEWEB)

This study has confirmed large seasonal and daily variations of Rn in soil gas, developed models for the effects of temperature and moisture on air-water Rn partition, inhibited Rn diffusion from wet soil into sparse large air-filled pores and effects of diffusion into bedrock, demonstrated that organic matter is a major host for 226Ra in soils and that organic-bound Ra largely determines the proportion of 222Rn emanated to pore space, shown that in contrast 220Rn is emanated mainly from 224Ra in Fe-oxides, detected significant disequilibrium between 226Ra and 238U in organic matter and in some recent glacial soils, demonstrated by computer models that air convection driven by temperature differences is expected in moderately permeable soils on hillsides.

1993-05-01

315

Generation and mobility of radon in soil  

Energy Technology Data Exchange (ETDEWEB)

This study has confirmed large seasonal and daily variations of Rn in soil gas, developed models for the effects of temperature and moisture on air-water Rn partition, inhibited Rn diffusion from wet soil into sparse large air-filled pores and effects of diffusion into bedrock, demonstrated that organic matter is a major host for 226Ra in soils and that organic-bound Ra largely determines the proportion of 222Rn emanated to pore space, shown that in contrast 220Rn is emanated mainly from 224Ra in Fe-oxides, detected significant disequilibrium between 226Ra and 238U in organic matter and in some recent glacial soils, demonstrated by computer models that air convection driven by temperature differences is expected in moderately permeable soils on hillsides.

1993-01-01

316

Comparative dosimetry for screen film systems and intensifier fluorography in urinary incontinence of women  

International Nuclear Information System (INIS)

In 16 female patients wick colpourethrocystography was performed directly successively with large-size films as well as medium-size films (intensifier fluorography). The area exposure products were measured by a dosemeter closely attached to the diaphragm and separately for radiography and fluorography, resp. Surface doses as well as organ doses were calculated according to Rosenstein. The average radiatin doses of the active bone marrow were 6.03 mGy for examination with large-size films and 1.27 mGy for fluorography; the average gonadal doses were 7.45 mGy and 1.56 mGy, resp. The portion of fluoroscopy in radiation exposure amounted to 14.8% in large-size film examination, but was 74.0% in medium-size examination. Thus the comparative results revealed a significant reduction of the patient's radiation dose by application of intensifier fluorography in colpourethrocystography.

1987-01-01

317

An efficient algorithm for the design of decentralized output feedback power system stabilizer  

Science.gov (United States)

A new algorithm for the design of decentralized output feedback stabilizers for large-scale electric power systems is presented in this paper. In the proposed approach, the generators which are most effective for stabilizer applications are first identified by using participation factors. Then an efficient algorithm based on decentralized pole assignment is proposed for the determination of the parameters of the power system stabilizers which, due to the difficulty associated with the communication among the geographically dispersed generating stations in a large power system, are essentially decentralized compensators using local generator outputs as their feedback signals. The proposed method is computationally efficient and can be applied to any large-scale system. The simplicity and effectiveness of the proposed method are demonstrated by an example of stabilizer design for a practical power system.

1988-08-01

318

A network security case study; The Los Alamos National Laboratory integrated computer network  

Energy Technology Data Exchange (ETDEWEB)

This paper reports on a study to validate the Graphical Network Representation (GRPHREP) model which is being conducted on the Los Alamos National Laboratory Integrated Computer Network (ICN). The GRPHREP model is a software system application based on graph theory and object-oriented programming methodologies. It codified the Department of Energy (DOE) Order 5637.1, which is concerned with classified computer secret policy, restrictions, and requirements. The Los Alamos ICN is required to control access to and support large-scale scientific and administrative computing. Thus, large-scale scientific and administrative computing. Thus we felt that this large, complex, and dynamic network would provide a good test for the graphical and functional capabilities of the model. Furthermore, the ICN is composed of multiple partitions that reflect the sensitivity and classification of the computation (data) and designate the ...

1991-01-01

319

What Do We Feed to Food-Production Animals? A Review of Animal Feed Ingredients and Their Potential Impacts on Human Health  

UK PubMed Central (United Kingdom)

ObjectiveAnimal feeding practices in the United States have changed considerably over the past century. As large-scale, concentrated production methods have become the predominant...Full Text Available

2007-05-01

320

Variants within the yeast Ty sequence family encode a class of structurally conserved proteins.  

UK PubMed Central (United Kingdom)

The Ty transposable elements of Saccharomyces cerevisiae form a heterogeneous family within which two broad structural classes (I and II) exist. The two classes differ by two large substitutions and...Full Text Available

1985-06-11

321

Utility of Recycled Bedding for Laboratory Rodents  

UK PubMed Central (United Kingdom)

Animal facilities generate a large amount of used bedding containing excrement as medical waste. We developed a recycling system for used bedding that involves soft hydrothermal processing. In this...Full Text Available

2009-07-01

322

Using microarrays to identify positional candidate genes for QTL: the case study of ACTH response in pigs  

UK PubMed Central (United Kingdom)

BackgroundMicroarray studies can supplement QTL studies by suggesting potential candidate genes in the QTL regions, which by themselves are too large to provide a limited selection...Full Text Available

323

University of Tennessee deploys force10 switch for CERN work  

CERN Multimedia

"Force20 networks, the pioneer in building and securing reliable networks, today announced that the University of Tennessee physics department has deployed the C300 resilient switch to analyze data form CERN's Large Hadron Collider." (1/2 page)

2007-01-01

324

Tissue Effect on Genetic Control of Transcript Isoform Variation  

UK PubMed Central (United Kingdom)

Current genome-wide association studies (GWAS) are moving towards the use of large cohorts of primary cell lines to study a disease of interest and to assign biological relevance to the genetic signals...Full Text Available

2009-08-01

325

Tight Blood Glucose Control Is Renoprotective in Critically Ill Patients  

UK PubMed Central (United Kingdom)

Two large, prospective, randomized, controlled trials have shown a beneficial effect of intensive insulin therapy (IIT) on the kidney function of critically ill patients. The data from these trials...Full Text Available

2008-03-01

326

The influence of tethered epidermal growth factor on connective tissue progenitor colony formation  

UK PubMed Central (United Kingdom)

Strategies to combine aspirated marrow cells with scaffolds to treat connective tissue defects are gaining increasing clinical attention and use. In situations such as large defects where initial...Full Text Available

2009-09-01

327

The human peripheral subunit-binding domain folds rapidly while overcoming repulsive Coulomb forces  

UK PubMed Central (United Kingdom)

Peripheral subunit binding domains (PSBDs) are integral parts of large multienzyme complexes involved in carbohydrate metabolism. PSBDs facilitate shuttling of prosthetic groups between different catalytic...Full Text Available

2010-09-01

328

The evolution of fossoriality and the adaptive role of horns in the Mylagaulidae (Mammalia: Rodentia)  

UK PubMed Central (United Kingdom)

Ceratogaulus, a member of the extinct fossorial rodent clade Mylagaulidae, is the only known rodent with horns and the smallest known horned mammal. The function of the large, dorsally...Full Text Available

2005-08-22

329

The elaborate structure of spider silk  

UK PubMed Central (United Kingdom)

Biomaterials, having evolved over millions of years, often exceed man-made materials in their properties. Spider silk is one outstanding fibrous biomaterial which consists almost entirely of large proteins....Full Text Available

2008-10-01

330

The conversion of DDT to DDE by some anophelines  

UK PubMed Central (United Kingdom)

The metabolism of DDT has been followed in pure lines of laboratory-reared resistant and susceptible anophelines using gas-liquid chromatography. Relatively large amounts of DDE were formed in...Full Text Available

1964-01-01

331

The Vasoactive Potential of Kisspeptin-10 in the Peripheral Vasculature  

UK PubMed Central (United Kingdom)

Splice products of the Kiss1 protein (kisspeptins) have been shown to be involved in a diverse range of functions, including puberty, metastasis and vasoconstriction in large human arteries. Circulating...Full Text Available

332

The Metabolism of Oat Leaves during Senescence  

UK PubMed Central (United Kingdom)

When the detached first leaves of green or etiolated oat (Avena sativa cv. Victory) seedlings senesce in the dark, their oxygen consumption shows a large increase, beginning after 24...Full Text Available

1974-09-01

333

The Mechanism and the Magnitude of Flow Boiling Augmentation in Tubes with Discrete Surface Roughness Elements (III).  

Science.gov (United States)

Related to other research on the effectiveness of flow boiling heat transfer augmentation using various types of turbulators this investigation comprises a definitive study of the effect of large discrete roughness elements on heat transfer over the entir...

1972-01-01

334

The Importance of Poisoning vs. Road Traffic Injuries as a Cause of Death in Rural Sri Lanka  

UK PubMed Central (United Kingdom)

BackgroundRoad traffic crashes are considered by the WHO to be the most important global cause of death from injury. However, this may not be true for large areas of rural Asia where...Full Text Available

335

The Formation of Anthocyanic Vacuolar Inclusions in Arabidopsis thaliana and Implications for the Sequestration of Anthocyanin Pigments  

UK PubMed Central (United Kingdom)

Anthocyanins are flavonoid pigments that accumulate in the large central vacuole of most plants. Inside the vacuole, anthocyanins can be found uniformly distributed or as part of sub-vacuolar pigment...Full Text Available

2010-01-01

336

The Exceptionally Large Genome of Hendra Virus: Support for Creation of a New Genus within the Family Paramyxoviridae  

UK PubMed Central (United Kingdom)

An outbreak of acute respiratory disease in Hendra, a suburb of Brisbane, Australia, in September 1994 resulted in the deaths of 14 racing horses and a horse trainer. The causative agent was a new member...Full Text Available

2000-11-01

337

The Caenorhabditis elegans Elongator Complex Regulates Neuronal ?-tubulin Acetylation  

UK PubMed Central (United Kingdom)

Although acetylated α-tubulin is known to be a marker of stable microtubules in neurons, precise factors that regulate α-tubulin acetylation are, to date, largely unknown. Therefore,...Full Text Available

2010-01-01

338

Test Cases - CFL3D - NASA  

Science.gov (United States)

Jun 10, 2011 ... Subsonic flow past a semi-infinite flat plate is modeled at Reynolds number 6 ..... data is taken from Cook, McDonald, and Firmin, AGARD-AR-138, 1979, p. ...... too large a time-averaged separation bubble behind the hump. ...

339

Synthesis and characterization of PVP-coated large core iron oxide nanoparticles as an MRI contrast agent  

UK PubMed Central (United Kingdom)

The purpose of this study was to synthesize biocompatible polyvinylpyrrolidone (PVP)-coated iron oxide (PVP-IO) nanoparticles and to evaluate their efficacy as a magnetic resonance imaging (MRI)...Full Text Available

2008-04-01

340

Surgical Management of Solid-Pseudopapillary Neoplasms of the Pancreas (Franz or Hamoudi Tumors): A Large Single-Institutional Series  

UK PubMed Central (United Kingdom)

BACKGROUNDSolid-pseudopapillary neoplasms (SPNs) are rare pancreatic tumors with malignant potential. Clinicopathologic characteristics and outcomes of patients with...Full Text Available

2009-05-01

341

Surge Capacity for Response to Bioterrorism in Hospital Clinical Microbiology Laboratories  

UK PubMed Central (United Kingdom)

Surge capacity is the ability to rapidly mobilize to meet an increased demand. While large amounts of federal funding have been allocated to public health laboratories, little federal funding has been...Full Text Available

2003-12-01

342

Structure of lipid bilayers  

UK PubMed Central (United Kingdom)

The quantitative experimental uncertainty in the structure of fully hydrated, biologically relevant, fluid (Lα) phase lipid bilayers has been too large to...Full Text Available

2000-11-10

343

Structure and Reaction Mechanism of Basil Eugenol Synthase  

UK PubMed Central (United Kingdom)

Phenylpropenes, a large group of plant volatile compounds that serve in multiple roles in defense and pollinator attraction, contain a propenyl side chain. Eugenol synthase (EGS) catalyzes the reductive...Full Text Available

344

Stabilization of lignin peroxidases in white rot fungi by tryptophan.  

UK PubMed Central (United Kingdom)

Supplementation of various cultures of white rot fungi with tryptophan was found to have a large stimulatory effect on lignin peroxidase activity levels. This enhancement was greater than that observed...Full Text Available

1997-07-01

345

Specific genetic modifications of domestic animals by gene targeting and animal cloning  

UK PubMed Central (United Kingdom)

The technology of gene targeting through homologous recombination has been extremely useful for elucidating gene functions in mice. The application of this technology was thought impossible in the large...Full Text Available

346

Species-specific Fungal DNA in Airborne Dust as Surrogate for Occupational Mycotoxin Exposure?  

UK PubMed Central (United Kingdom)

Possible health risks associated with occupational inhalation of mycotoxin-containing dust remain largely unknown, partly because methods for mycotoxin detection are not sensitive enough for the small...Full Text Available

347

Single Molecule Source Reagents for CVD of Beta Silicon Carbide.  

Science.gov (United States)

Beta silicon carbide is an excellent candidate semiconductor material for demanding applications in high power and high temperature electronic devices due to its high breakdown voltage, relatively large band gap, high thermal conductivity and high melting...

1991-01-01

348

Simultaneous rapid chemical synthesis of over one hundred oligonucleotides on a microscale  

UK PubMed Central (United Kingdom)

An inexpensive, extremely rapid manual method for simultaneous synthesis of large numbers of oligodeoxyribonucleotides on 50 or 150 nanomole scale is described. The oligonucleotides are assembled in...Full Text Available

1984-04-01

349

Short-amplitude high-frequency wing strokes determine the aerodynamics of honeybee flight  

UK PubMed Central (United Kingdom)

Most insects are thought to fly by creating a leading-edge vortex that remains attached to the wing as it translates through a stroke. In the species examined so far, stroke amplitude is large, and...Full Text Available

2005-12-13

350

Sequence features that drive human promoter function and tissue specificity  

UK PubMed Central (United Kingdom)

Promoters are important regulatory elements that contain the necessary sequence features for cells to initiate transcription. To functionally characterize a large set of human promoters, we measured...Full Text Available

2010-07-01

351

Secular changes in height, weight and body mass index in Hong Kong Children  

UK PubMed Central (United Kingdom)

BackgroundLarge population growth surveys of children and adolescents aged 6 to 18 y were undertaken in Hong Kong in 1963 and 1993. The global epidemic of obesity is a major public...Full Text Available

352

Seal is successful at Italys largest pumped storage plant  

British Library Electronic Table of Contents (United Kingdom)

A HydroSele S seal from James Walker has provided more than two years maintenance-free service at the large Entracque pumped-storage hydroelectric scheme in Italy.

2008-01-01

353

Roles of lead-binding proteins in mediating lead bioavailability.  

UK PubMed Central (United Kingdom)

The intracellular bioavailability of lead (Pb) at low dosage levels in major target organs such as the kidney and brain appears to be largely determined by complexation with a group of low molecular...Full Text Available

1998-12-01

354

Research on ethics in two large Human Biomonitoring projects ECNIS and NewGeneris: a bottom up approach  

UK PubMed Central (United Kingdom)

Assessment of ethical aspects and authorization by ethics committees have become a major constraint for health research including human subjects. Ethical reference values often are extrapolated from...Full Text Available

355

Research  

Wastenet

...5% of foods exceed the maximum pesticide residues level , EFSA says Monday, 12 July 2010 12:41 European foods are largely under the ...Maximum Pesticide Residues Level , according to EFSA: in 2008 only 3.5% of analysed samples exceeded the MRLs (4.2% ...

356

ReplicationDomain: a visualization tool and comparative database for genome-wide replication timing data  

UK PubMed Central (United Kingdom)

BackgroundEukaryotic DNA replication is regulated at the level of large chromosomal domains (0.5–5 megabases in mammals) within which replicons are activated relatively synchronously....Full Text Available

357

Relative threat and recognition ability in the responses of tropical mockingbirds to song playback  

UK PubMed Central (United Kingdom)

It has been suggested that individual recognition based on song may be constrained by repertoire size in songbirds with very large song repertoires. This hypothesis has been difficult to test...Full Text Available

2007-04-01

358

Relation of the One-Phase Stefan Problem to the Seepage of Liquids and Electrochemical Machining.  

Science.gov (United States)

The flow of water through a dam of fairly arbitrary shape is examined in the limit of large frictional drag on the flow. The relation of the problem to the one-phase Stefan problem and a problem of anodic smoothing is explored. Monotonicity and uniqueness...

1979-01-01

359

Recognition of Dual or Multiple Pathology in Skin Biopsies from Patients with HIV/AIDS  

UK PubMed Central (United Kingdom)

A large percentage of patients with HIV/AIDS will develop dermatological complications. Consequently, all practising clinicians and pathologists in regions with a high prevalence of HIV/AIDS must be...Full Text Available

360

Reactivity parameters in structure-activity relationship-based risk assessment of chemicals.  

UK PubMed Central (United Kingdom)

New approaches to the risk assessment process are needed that might be more definitive and satisfying to the scientific community, interest groups, and the public at large. This commentary examines...Full Text Available

1996-08-01

361

Rational design of DNA sequences for nanotechnology, microarrays and molecular computers using Eulerian graphs  

UK PubMed Central (United Kingdom)

Nucleic acids are molecules of choice for both established and emerging nanoscale technologies. These technologies benefit from large functional densities of ‘DNA processing elements’...Full Text Available

2004-01-01

362

Quantifiable Biomarkers of Normal Aging in the Japanese Medaka Fish (Oryzias latipes)  

UK PubMed Central (United Kingdom)

BackgroundSmall laboratory fish share many anatomical and histological characteristics with other vertebrates, yet can be maintained in large numbers at low cost for lifetime studies....Full Text Available

363

Quality control in laboratory investigations on Schistosoma mansoni on St Lucia, West Indies: a staff assessment scheme*  

UK PubMed Central (United Kingdom)

A method is described for the supervision of technicians engaged in microscopical screening of large numbers of stools for Schistosoma mansoni ova. The scheme presents graphically...Full Text Available

1978-01-01

364

QED processes on e"+e"#+-#-, ep-, #gamma##gamma#-colliders  

International Nuclear Information System (INIS)

The present status of theoretical description of deep-inelastic lepton-nucleon as well as large angle Bhabha scattering with account for radiative corrections in the leading and next-to-leading approximations are reviewed. Also considered is a build-up principle and physical programme of the photon-photon colliders

365

Problem-centric Organization and Visualization of Patient Imaging and Clinical Data  

UK PubMed Central (United Kingdom)

A patient’s electronic medical record contains a large amount of unstructured textual information. As patient records become increasingly dense owing to an aging population and increased occurrence...Full Text Available

2009-03-01

366

Prevalence and determinants of pain and pain-related disability in urban and rural settings in southeastern Ontario  

UK PubMed Central (United Kingdom)

BACKGROUND:Canadian chronic pain prevalence estimates range from 11% to 66%, are affected by sampling and measurement bias, and largely represent urban settings.OBJECTIVES:To...Full Text Available

2006-01-01

367

Population genetic analysis of large sequence polymorphisms in Plasmodium falciparum blood-stage antigens  

UK PubMed Central (United Kingdom)

Plasmodium falciparum, the causative agent of human malaria, invades host erythrocytes using several proteins on the surface of the invasive merozoite, which have been proposed...Full Text Available

2010-03-01

368

Podcast The Large Hadron Collider and the Search for the Higgs-Boson  

CERN Document Server

When it was first developed, the standard model predicted a collection of particles, and thanks to more and more powerful colliders, physicsists have been able to find them all except one: the Higgs-Boson.

2008-01-01

369

PAGETOID RETICULOSIS IN A 5 YEAR OLD BOY  

UK PubMed Central (United Kingdom)

We present a rare case of pagetoid reticulosis arising in a five year old white boy. He had a history of a large chronic erythematous, scaly patch on his left buttock that had shown intermittent...Full Text Available

2008-04-01

370

Overcoming the challenges of membrane protein crystallography  

UK PubMed Central (United Kingdom)

Membrane protein structural biology is still a largely unconquered area, given that approximately 25% of all proteins are membrane proteins and yet less than 150 unique structures are available. Membrane...Full Text Available

2008-10-01

371

Outpatient percutaneous coronary intervention: Ready for prime time?  

UK PubMed Central (United Kingdom)

Outpatient practice after percutaneous coronary intervention (PCI) is gaining momentum due to constantly optimizing results. Furthermore, the availability of limited beds to handle the large volume...Full Text Available

2007-10-01

372

On Being the Right Size: The Impact of Population Size and Stochastic Effects on the Evolution of Drug Resistance in Hospitals and the Community  

UK PubMed Central (United Kingdom)

The evolution of drug resistant bacteria is a severe public health problem, both in hospitals and in the community. Currently, some countries aim at concentrating highly specialized services in large...Full Text Available

2011-04-01

373

Nutrient supply, growth and development of field vegetables  

Environmental Research Database

DescriptionThe UK horticulture and agriculture industries rely on large inputs of mineral nitrogen (N), phosphorus (P) and potassium (K) fertilisers to maintain product yield and quality. Recovery of applied fertilisers by field crops is inefficient (routinely

2007-01-31

374

Norway on the battery; Norge paa batteri  

Energy Technology Data Exchange (ETDEWEB)

What if Norway will arrange for a large-scale investment in electric cars? In 2020 the regular Norwegian drive around in an electric car. She does it because it pays, because it is better for the environment - and because it is practically feasible. This is the starting point for a four-year research work led by SINTEF. (AG)

2009-07-01

375

Negative Subtraction Hybridization: An efficient method to isolate large numbers of condition-specific cDNAs  

UK PubMed Central (United Kingdom)

BackgroundThe construction of cDNA libraries is a useful tool to understand gene expression in organisms under different conditions, but random sequencing of unbiased cDNA collections...Full Text Available

376

NASCENT: An automatic protein interaction network generation tool for non-model organisms  

UK PubMed Central (United Kingdom)

Large quantity of reliable protein interaction data are available for model organisms in public depositories (e.g., MINT, DIP, HPRD, INTERACT). Most data correspond to experiments with the proteins...Full Text Available

377

Mutations in TPRN Cause a Progressive Form of Autosomal-Recessive Nonsyndromic Hearing Loss  

UK PubMed Central (United Kingdom)

We performed genome-wide homozygosity mapping in a large consanguineous family from Morocco and mapped the autosomal-recessive nonsyndromic hearing loss (ARNSHL) in this family to the DFNB79...Full Text Available

2010-03-12

378

Molecular Architecture of the Centriole Proteome: The Conserved WD40 Domain Protein POC1 Is Required for Centriole Duplication and Length Control  

UK PubMed Central (United Kingdom)

Centrioles are intriguing cylindrical organelles composed of triplet microtubules. Proteomic data suggest that a large number of proteins besides tubulin are necessary for the formation and maintenance...Full Text Available

2009-02-15

379

Mobilizing diversity: transposable element insertions in genetic variation and disease  

UK PubMed Central (United Kingdom)

Transposable elements (TEs) comprise a large fraction of mammalian genomes. A number of these elements are actively jumping in our genomes today. As a consequence, these insertions provide a source...Full Text Available

380

Microbial treatment of high explosives  

Energy Technology Data Exchange (ETDEWEB)

Both DOE and DOD use water and/or steam in the process of removing high explosives, resulting in large quantities of contaminated water, which is then run through activated carbon, which then has to be decontaminated. Research has been underway to utilize microorganisms to degrade RDX and HMX.

1997-07-01

381

Massachusetts' approach to the prevention of heart disease, cancer, and stroke.  

UK PubMed Central (United Kingdom)

Heart disease, cancer, and cerebrovascular disease together cause more than two out of three deaths in the United States annually. These three diseases are largely a result of widespread risk factors...Full Text Available

1986-01-01

382

Mapping strain exerted on blood vessel walls using deuterium double-quantum-filtered MRI  

UK PubMed Central (United Kingdom)

A technique is described for displaying distinct tissue layers of large blood vessel walls as well as measuring their mechanical strain. The technique is based on deuterium double-quantum-filtered (DQF)...Full Text Available

1998-04-14

383

Malignant pineal germ-cell tumors: An analysis of cases from three tumor registries  

UK PubMed Central (United Kingdom)

The exact incidence of pineal germ-cell tumors is largely unknown. The tumors are rare, and the number of patients with these tumors, as reported in clinical series, has been limited. The goal of this...Full Text Available

2008-04-01

384

Malignant melanoma of the skin among workers in a telecommunications industry: mortality study 1976-83.  

UK PubMed Central (United Kingdom)

An incidence study of malignant melanoma of the skin (MMS), conducted previously among the workers of four plants of a large telecommunications industry located in Montreal, Canada, showed a standardised...Full Text Available

1992-10-01

385

Malignant Change in an Epidermal Cyst Over Gluteal Region  

UK PubMed Central (United Kingdom)

A 72-year-old male presented with a large ulceroproliferative lesion over left gluteal region. After histopathological confirmation of squamous cell carcinoma, the lesion was excised with wide margins....Full Text Available

2011-01-01

386

MELCOR analyses of NUPEC`s large-scale hydrogen mixing test-II  

Energy Technology Data Exchange (ETDEWEB)

NUPEC has carried out hydrogen mixing tests to investigate hydrogen distribution behavior within a model containment and to provide a set of experimental data for validation of severe accident analysis codes.

1995-12-31

387

MAPPING THE INITIATOR BINDING TAF2 SUBUNIT IN THE STRUCTURE OF HYDRATED YEAST TFIID  

UK PubMed Central (United Kingdom)

SummaryThe general transcription factor TFIID is a large multi-subunit complex required for the transcription of most protein-encoding genes by RNA polymerase II. Taking advantage...Full Text Available

2009-03-11

388

Luetic aortopathy: Revisited  

UK PubMed Central (United Kingdom)

We report a case of 38-year-old male, who presented with a large pulsatile swelling on the left side of the anterior chest wall of 4 months’ duration with a gradual increase in size. He gave...Full Text Available

2010-07-01

389

Low level of polymorphism in two putative NPR1 homologs in the Vitaceae family  

UK PubMed Central (United Kingdom)

BackgroundGrapevine is subjected to numerous pests and diseases resulting in the use of phytochemicals in large quantities. The will to decrease the use of phytochemicals leads to...Full Text Available

390

Localizing potentially active post-transcriptional regulations in the Ewing's sarcoma gene regulatory network  

UK PubMed Central (United Kingdom)

BackgroundA wide range of techniques is now available for analyzing regulatory networks. Nonetheless, most of these techniques fail to interpret large-scale transcriptional data...Full Text Available

391

Large-scale association analysis of TNF/LTA gene region polymorphisms in type 2 diabetes  

UK PubMed Central (United Kingdom)

BackgroundThe TNF/LTA locus has been a long-standing T2D candidate gene. Several studies have examined association of TNF/LTA...Full Text Available

392

Large-scale Analysis of Thermo-stable, Mammalian Proteins Provides Insights into the Intrinsically Disordered Proteome  

UK PubMed Central (United Kingdom)

Intrinsically disordered proteins are predicted to be highly abundant and play broad biological roles in eukaryotic cells. In particular, by virtue of their structural malleability and propensity...Full Text Available

2009-01-01

393

Large scale steam valve test: Performance testing of large butterfly valves and full scale high flowrate steam testing  

Energy Technology Data Exchange (ETDEWEB)

This report presents the results of the design testing of large (36-inch diameter) butterfly valves under high flow conditions. The two butterfly valves were pneumatically operated air-open, air-shut valves (termed valves 1 and 2). These butterfly valves were redesigned to improve their ability to function under high flow conditions. Concern was raised regarding the ability of the butterfly valves to function as required with high flow-induced torque imposed on the valve discs during high steam flow conditions. High flow testing was required to address the flow-induced torque concerns. The valve testing was done using a heavily instrumented piping system. This test program was called the Large Scale Steam Valve Test (LSSVT). The LSSVT program demonstrated that the redesigned valves operated satisfactorily under high flow conditions.

1995-05-01

395

Joint Research Centre - JRC - European Commission  

Wastenet

... The high resolution imagery , collected over Rio de Janeiro, Brazil, included a mixture of large commercial buildings and private houses, as well as the airport and some community parks. 10/08/11 Read more Top EU R&D companies expect a 5% ...

396

Ixodes scapularis tick serine proteinase inhibitor (serpin) gene family; annotation and transcriptional analysis  

UK PubMed Central (United Kingdom)

BackgroundSerine proteinase inhibitors (Serpins) are a large superfamily of structurally related, but functionally diverse proteins that control essential proteolytic pathways in...Full Text Available

397

Isolation of Bacillus thuringiensis from Stored Tobacco and Lasioderma serricorne (F.)  

UK PubMed Central (United Kingdom)

Bacillus thuringiensis was isolated from dried tobacco residues and dead tobacco beetles (Lasioderma serricorne (F.); Coleoptera: Anobiidae) collected in a large number...Full Text Available

1994-01-01

398

Isolation and partial characterization of a specific alpha-fetoprotein receptor on human monocytes.  

UK PubMed Central (United Kingdom)

Since a large body of data has suggested a significant role for alpha-fetoprotein (AFP) in the regulation of the immune response at a number of levels, we examined the possibility of a specific receptor...Full Text Available

1992-10-01

399

Is globalization good for your health?  

UK PubMed Central (United Kingdom)

Four points are made about globalization and health. First, economic integration is a powerful force for raising the incomes of poor countries. In the past 20 years several large developing countries...Full Text Available

2001-01-01

400

Intrinsic expression of host genes and intronic miRNAs in prostate carcinoma cells  

UK PubMed Central (United Kingdom)

BackgroundRecent data show aberrant and altered expression of regulatory noncoding micro (mi) RNAs in prostate cancer (PCa). A large number of miRNAs are encoded in organized intronic...Full Text Available

401

Integrating diverse databases into an unified analysis framework: a Galaxy approach  

UK PubMed Central (United Kingdom)

Recent technological advances have lead to the ability to generate large amounts of data for model and non-model organisms. Whereas, in the past, there have been a relatively small number of central...Full Text Available

402

Integrase-directed recovery of functional genes from genomic libraries  

UK PubMed Central (United Kingdom)

Large population sizes, rapid growth and 3.8 billion years of evolution firmly establish microorganisms as a major source of the planet's biological and genetic diversity. However, up to 99% of the...Full Text Available

2009-09-01

403

Instrumentation and Controls Division progress report, July 1, 1982-July 1, 1984. Volume 1  

Energy Technology Data Exchange (ETDEWEB)

Progress is briefly summarized for a large number of projects in the areas of research instruments, measurement and controls engineering, reactor systems, and maintenance management. (LEW)

1984-12-01

404

Indole-Diterpene Gene Cluster from Aspergillus flavus  

UK PubMed Central (United Kingdom)

Aflatrem is a potent tremorgenic mycotoxin produced by the soil fungus Aspergillus flavus and is a member of a large structurally diverse group of secondary metabolites known as indole-diterpenes....Full Text Available

2004-11-01

405

Indian vaccine innovation: the case of Shantha Biotechnics  

UK PubMed Central (United Kingdom)

BackgroundAlthough the World Health Organization had recommended that every child be vaccinated for Hepatitis B by the early 1980s, large multinational pharmaceutical companies held...Full Text Available

406

In vitro digestibility of fern and gymnosperm foliage: implications for sauropod feeding ecology and diet selection  

UK PubMed Central (United Kingdom)

Sauropod dinosaurs, the dominant herbivores throughout the Jurassic, challenge general rules of large vertebrate herbivory. With body weights surpassing those of any other megaherbivore, they relied...Full Text Available

2008-05-07

407

Implications of abrupt climate change.  

UK PubMed Central (United Kingdom)

Records of past climates contained in ice cores, ocean sediments, and other archives show that large, abrupt, widespread climate changes have occurred repeatedly in the past. These changes were especially...Full Text Available

2004-01-01

408

Impact of intraoperative lung-protective interventions in patients undergoing lung cancer surgery  

UK PubMed Central (United Kingdom)

IntroductionIn lung cancer surgery, large tidal volume and elevated inspiratory pressure are known risk factors of acute lung (ALI). Mechanical ventilation with low tidal volume...Full Text Available

2009-01-01

409

Imaging of calcium transients in skeletal muscle fibers.  

UK PubMed Central (United Kingdom)

Epifluorescence images of Ca2+ transients elicited by electrical stimulation of single skeletal muscle fibers were studied with fast imaging techniques that take advantage of the large fluorescence...Full Text Available

1991-01-01

410

Identifying related L1 retrotransposons by analyzing 3' transduced sequences  

UK PubMed Central (United Kingdom)

BackgroundA large fraction of the human genome is attributable to L1 retrotransposon sequences. Not only do L1s themselves make up a significant portion of the genome, but L1-encoded...Full Text Available

2003-01-01

411

ISS022-E-8261 - The Gateway to Astronaut Photography of Earth  

Science.gov (United States)

Features: CHUQUICAMATA, LARGE OPEN PIT MINING OPERATIONS, ROADS, HILLS Center Point Latitude: -22.3 Center Point Longitude: -68.9 (Negative numbers indicate ...

412

ISS022-E-8260 - The Gateway to Astronaut Photography of Earth  

Science.gov (United States)

Features: CHUQUICAMATA, LARGE OPEN PIT MINING OPERATIONS, ROADS, HILLS Center Point Latitude: -22.3 Center Point Longitude: -68.9 (Negative numbers indicate ...

413

IMO Momentenlager GmbH: Reliable ball bearings made in Middle Franconia; IMO Momentenlager GmbH: Zuverlaessige Kugellager aus Mittelfranken  

Energy Technology Data Exchange (ETDEWEB)

IMO Momentenlager GmbH of Gremsdorf near Nuremberg produces large rotary bearings for ENERCON wind power systems, preferably for the E-70 and E-82 generators. (orig.)

2007-07-01

414

Hsp12.6 Expression Is Inducible by Host Immunity in Adult Worms of the Parasitic Nematode Nippostrongylus brasiliensis  

UK PubMed Central (United Kingdom)

Heat shock proteins (Hsp) are a family of stress-inducible molecular chaperones that play multiple roles in a wide variety of animals. However, the roles of Hsps in parasitic nematodes remain largely...Full Text Available

415

How DNA coiling enhances target localization by proteins  

UK PubMed Central (United Kingdom)

Many genetic processes depend on proteins interacting with specific sequences on DNA. Despite the large excess of nonspecific DNA in the cell, proteins can locate their targets rapidly. After initial...Full Text Available

2008-10-14

416

Holographic and Quark-Hadron Duality for Form Factors  

Energy Technology Data Exchange (ETDEWEB)

We study the large-Q{sup 2} behavior of the meson form factor F{sub M} (Q{sup 2}) constructed using the holographic light-front wave functions.

2006-05-15

417

High-energy reaction cross sections of light nuclei  

Energy Technology Data Exchange (ETDEWEB)

The high-energy reaction cross sections of Li and Be isotopes are calculated using a simplified Glauber model and densities constrained by the empirical binding energies. We find excellent agreement with experiment, reproducing the large increase for the most neutron-rich nuclei.

1989-03-01

418

High-density multiplex detection of nucleic acid sequences: oligonucleotide ligation assay and sequence-coded separation.  

UK PubMed Central (United Kingdom)

We describe a non-isotopic, semi-automated method for large-scale multiplex analysis of nucleic acid sequences, using the cystic fibrosis transmembrane regulator (CFTR) gene as an example. Products...Full Text Available

1994-10-25

419

High genetic variability and low local diversity in a population of arbuscular mycorrhizal fungi  

UK PubMed Central (United Kingdom)

Arbuscular mycorrhizal fungi (AMF) are ecologically important root symbionts of most terrestrial plants. Ecological studies of AMF have concentrated on differences between species; largely assuming...Full Text Available

2004-02-24

420

High Prevalence of Extended-Spectrum Beta Lactamases among Salmonella enterica Typhimurium Isolates from Pediatric Patients with Diarrhea in China  

UK PubMed Central (United Kingdom)

We investigated the extended-spectrum beta lactamases among 62 Salmonella enterica Typhimurium isolates recovered from children with diarrhea in a Chinese pediatric hospital. A large...Full Text Available

421

High Efficiency Solar Cell on Low Cost Metal Foil Substrate  

Science.gov (United States)

During Phase II multi-junction solar cell will be grown on the large grain thin film produced during Phase I on flexible/low cost metal foil substrate. ...

422

Genetic susceptibility to systemic lupus erythematosus in the genomic era  

UK PubMed Central (United Kingdom)

Our understanding of the genetic basis of systemic lupus erythematosus (SLE) has been rapidly advanced using large-scale, case–control, candidate gene studies as well as genome-wide...Full Text Available

2010-12-01

423

Genetic architecture of complex traits: Large phenotypic effects and pervasive epistasis  

UK PubMed Central (United Kingdom)

The genetic architecture of complex traits underlying physiology and disease in most organisms remains elusive. We still know little about the number of genes that underlie these traits, the magnitude...Full Text Available

2008-12-16

424

Genetic Elucidation of Human Hyperosmia to Isovaleric Acid  

UK PubMed Central (United Kingdom)

The genetic basis of odorant-specific variations in human olfactory thresholds, and in particular of enhanced odorant sensitivity (hyperosmia), remains largely unknown. Olfactory receptor (OR) segregating...Full Text Available

2007-11-01

425

General lack of global dosage compensation in ZZ/ZW systems? Broadening the perspective with RNA-seq  

UK PubMed Central (United Kingdom)

BackgroundSpecies with heteromorphic sex chromosomes face the challenge of large-scale imbalance in gene dose. Microarray-based studies in several independent male heterogametic...Full Text Available

426

Gene-gene and gene-environment interactions: new insights into the prevention, detection and management of coronary artery disease  

UK PubMed Central (United Kingdom)

Despite the recent success of genome-wide association studies (GWASs) in identifying loci consistently associated with coronary artery disease (CAD), a large proportion of the genetic components of...Full Text Available

427

Gene-Environment Interactions in Schizophrenia: Review of Epidemiological Findings and Future Directions  

UK PubMed Central (United Kingdom)

Concern is building about high rates of schizophrenia in large cities, and among immigrants, cannabis users, and traumatized individuals, some of which likely reflects the causal influence of environmental...Full Text Available

2008-11-01

428

Gallium Disrupts Iron Uptake by Intracellular and Extracellular Francisella Strains and Exhibits Therapeutic Efficacy in a Murine Pulmonary Infection Model ?  

UK PubMed Central (United Kingdom)

Francisella tularensis requires iron (Fe) for growth, but the biologic sources of Fe for this organism are largely unknown. We found that Francisella sp. growing in...Full Text Available

2010-01-01

429

Fusion Reactor Radioactive Waste Management.  

Science.gov (United States)

Quantities and compositions of non-tritium radioactive waste are estimated for some current conceptual fusion reactor designs, and disposal of large amounts of radioactive waste appears necessary. Although the initial radioactivity of fusion reactor and f...

1976-01-01

430

Functional Interactions between Retinoblastoma and c-MYC in a Mouse Model of Hepatocellular Carcinoma  

UK PubMed Central (United Kingdom)

Inactivation of the RB tumor suppressor and activation of the MYC family of oncogenes are frequent events in a large spectrum of human cancers. Loss of RB function and MYC activation are thought to...Full Text Available

431

Food  

Wastenet

...5% of foods exceed the maximum pesticide residues level , EFSA says Monday, 12 July 2010 12:41 European foods are largely under the ...Maximum Pesticide Residues Level , according to EFSA: in 2008 only 3.5% of analysed samples exceeded the MRLs (4.2% ...

432

Foam Filled Muzzle Blast Reducing Device.  

Science.gov (United States)

A device for reducing the muzzle blast and flash from large caliber guns is disclosed. A container having a plurality of internal chambers and baffle plates filled with an aqueous foam is mounted to the muzzle of the gun barrel. The foam and chambers co-o...

1982-01-01

433

Fast, Scalable, Bayesian Spike Identification for Multi-Electrode Arrays  

UK PubMed Central (United Kingdom)

We present an algorithm to identify individual neural spikes observed on high-density multi-electrode arrays (MEAs). Our method can distinguish large numbers of distinct neural units, even when spikes...Full Text Available

434

Far-Red Light-Induced Changes in Intracellular Potentials of Spinach Mesophyll Cells  

UK PubMed Central (United Kingdom)

In green plants, the large bioelectric changes that photosynthetically active light stimulates make it difficult to observe electrical potential changes related to phytochrome photoconversion. As a...Full Text Available

1983-11-01

435

Factors affecting birth weight in sheep: maternal environment  

UK PubMed Central (United Kingdom)

Knowledge of factors affecting variation in birth weight is especially important given the relationship of birth weight to neonatal and adult health. The present study utilises two large contemporary...Full Text Available

2007-01-01

436

Expression of leukotriene receptors in the rat dorsal root ganglion and the effects on pain behaviors  

UK PubMed Central (United Kingdom)

BackgroundLeukotrienes (LTs) belong to the large family of lipid mediators implicated in various inflammatory conditions such as asthma and rheumatoid arthritis. Four distinct types...Full Text Available

437

Expression and purification of a functional human hepatitis B virus polymerase  

UK PubMed Central (United Kingdom)

AIM: To identify a method for efficient large-scale purification of functional hepatitis B virus polymerase (HBV-Pol) without addition of cellular factors.METHODS: Full-length HBV-Pol (843 amino...Full Text Available

2010-12-07

438

Expansions, contractions, and fragility of the spinocerebellar ataxia type 10 pentanucleotide repeat in yeast  

UK PubMed Central (United Kingdom)

Spinocerebellar ataxia 10 (SCA10) is an autosomal dominant disease caused by large-scale expansions of the (ATTCT)n repeat within an intron of the human ATXN10 gene. In contrast...Full Text Available

2011-02-15

439

Exit from the Golgi Is Required for the Expansion of the Autophagosomal Phagophore in Yeast Saccharomyces cerevisiae  

UK PubMed Central (United Kingdom)

The delivery of proteins and organelles to the vacuole by autophagy involves membrane rearrangements that result in the formation of large vesicles called autophagosomes. The mechanism underlying autophagosome...Full Text Available

2010-07-01

440

Evolution of age at menarche and at onset of regular cycling in a large cohort of French women  

UK PubMed Central (United Kingdom)

BackgroundEarly exposure to ovarian hormones is considered to increase breast cancer incidence. The age at which the ovaries become functional is thus important.Full Text Available

2002-01-01

441

Evaluation of two commercial jet nebulisers and three compressors for the nebulisation of antibiotics.  

UK PubMed Central (United Kingdom)

Nebulised antibiotics have been shown to be beneficial in the treatment of lung infections in cystic fibrosis. Studies on the efficiency of nebuliser systems are constantly required in view of the large...Full Text Available

1994-10-01

442

Establishing the Irish Critical Care Trials Group: 'who wins in battle makes many calculations before the battle is fought'  

UK PubMed Central (United Kingdom)

Quality research, requiring large numbers of participants, in the intensive care unit (ICU) population requires multicentre collaboration. Although logistically challenging, this methodology reduces...Full Text Available

2008-01-01

443

Enzymatic control of anhydrobiosis-related accumulation of trehalose in the sleeping chironomid, Polypedilum vanderplanki  

UK PubMed Central (United Kingdom)

Larvae of an anhydrobiotic insect, Polypedilum vanderplanki, accumulate very large amounts of trehalose as a compatible solute on desiccation, but the molecular mechanisms underlying...Full Text Available

2010-10-01

444

Enhancing return-to-work in cancer patients, development of an intervention and design of a randomised controlled trial  

UK PubMed Central (United Kingdom)

BackgroundCompared to healthy controls, cancer patients have a higher risk of unemployment, which has negative social and economic impacts on the patients and on society at large....Full Text Available

445

Emergence of Switch-Like Behavior in a Large Family of Simple Biochemical Networks  

UK PubMed Central (United Kingdom)

Bistability plays a central role in the gene regulatory networks (GRNs) controlling many essential biological functions, including cellular differentiation and cell cycle control. However, establishing...Full Text Available

2011-05-01

446

Efficient Phagocytosis Requires Triacylglycerol Hydrolysis by Adipose Triglyceride Lipase*  

UK PubMed Central (United Kingdom)

Macrophage phagocytosis is an essential biological process in host defense and requires large amounts of energy. To date, glucose is believed to represent the prime substrate for ATP production in macrophages....Full Text Available

2010-06-25

447

Effects of small doses of ionizing radiation on human health  

Energy Technology Data Exchange (ETDEWEB)

The risks to human health from small doses of ionizing radiation raise questions which remain largely unanswered. This paper begins by explaining the historical background to this subject; it goes on to discuss recent developments and concludes with a personal view of the dose-reponse relationship. (author).

1997-12-01

448

Effects of small doses of ionizing radiation on human health  

International Nuclear Information System (INIS)

The risks to human health from small doses of ionizing radiation raise questions which remain largely unanswered. This paper begins by explaining the historical background to this subject; it goes on to discuss recent developments and concludes with a personal view of the dose-reponse relationship. (author).

1997-01-01

449

Effects of an Alpha-4 Integrin Inhibitor on Restenosis in a New Porcine Model Combining Endothelial Denudation and Stent Placement  

UK PubMed Central (United Kingdom)

Restenosis remains the main complication of balloon angioplasty and/or stent implantation. Preclinical testing of new pharmacologic agents preventing restenosis largely rely on porcine models, where...Full Text Available

450

Does Damage to DNA and Other Macromolecules Play a Role in Aging? If So, How?  

UK PubMed Central (United Kingdom)

One of the most pervasive ideas regarding the causes of aging is that longevity is constrained in large measure by damage to macromolecules. An increasing body of cellular and molecular data, generated...Full Text Available

2009-02-01

451

Development of an Integrated Medical Record System at a Large Hospital Using COSTAR as a Designing Tool  

UK PubMed Central (United Kingdom)

It is usually very complex to design an Integrated Information System in a hospital that includes both in-patient and out-patient medical care data. The difficulty appears because each department...Full Text Available

1982-11-02

452

Design of 240,000 orthogonal 25mer DNA barcode probes  

UK PubMed Central (United Kingdom)

DNA barcodes linked to genetic features greatly facilitate screening these features in pooled formats using microarray hybridization, and new tools are needed to design large sets of barcodes to allow...Full Text Available

2009-02-17

453

Decentralized Data Sharing of Tissue Microarrays for Investigative Research in Oncology  

UK PubMed Central (United Kingdom)

Tissue microarray technology (TMA) is a relatively new approach for efficiently and economically assessing protein and gene expression across large ensembles of tissue specimens. Tissue microarray technology...Full Text Available

454

Cytoplasmic Calcium Increases in Response to Changes in the Gravity Vector in Hypocotyls and Petioles of Arabidopsis Seedlings1  

UK PubMed Central (United Kingdom)

Plants respond to a large variety of environmental signals, including changes in the gravity vector (gravistimulation). In Arabidopsis (Arabidopsis thaliana) seedlings, gravistimulation...Full Text Available

2008-02-01

455

Cryptic invasion by a non-native genotype of the common reed, Phragmites australis, into North America  

UK PubMed Central (United Kingdom)

Cryptic invasions are a largely unrecognized type of biological invasion that lead to underestimation of the total numbers and impacts of invaders because of the difficulty in detecting them. The distribution...Full Text Available

2002-02-19

456

Cryoglobinaemia in rabbits hyperimmunized with a polyvalent pneumococcal vaccine  

UK PubMed Central (United Kingdom)

During the anamnestic response, the sera of four rabbits immunized with a polyvalent pneumococcal vaccine contained large amounts of cryoglobulins belonging to the G and M immunoglobulin classes. These...Full Text Available

1965-10-01

457

Crassulacean Acid Metabolism and Epiphytism Linked to Adaptive Radiations in the Orchidaceae1[OA  

UK PubMed Central (United Kingdom)

Species of the large family Orchidaceae display a spectacular array of adaptations and rapid speciations that are linked to several innovative features, including specialized pollination syndromes,...Full Text Available

2009-04-01

458

Coryneform bacteria in infectious diseases: clinical and laboratory aspects.  

UK PubMed Central (United Kingdom)

Coryneform isolates from clinical specimens frequently cannot be identified by either reference laboratories or research laboratories. Many of these organisms are skin flora that belong to a large number...Full Text Available

1990-07-01

459

Convection-enhanced delivery of maghemite nanoparticles: Increased efficacy and MRI monitoring  

UK PubMed Central (United Kingdom)

Convection-enhanced drug delivery (CED) is a novel approach to delivering drugs into brain tissue. Drugs are delivered continuously via a catheter, enabling large volume distributions of high drug concentrations...Full Text Available

2008-04-01

460

Consumer preferences for electric vehicles. Final report  

Energy Technology Data Exchange (ETDEWEB)

A small-sample survey of consumer preferences for a second car - featuring both conventional and electric vehicle choices - indicates a proelectric bias. The potential of electric cars in the utility market largely depends on dramatic improvements in battery technology and the right mix of electricity and gasoline prices.

1986-06-01

461

Concurrent Exposure of Bottlenose Dolphins (Tursiops truncatus) to Multiple Algal Toxins in Sarasota Bay, Florida, USA  

UK PubMed Central (United Kingdom)

Sentinel species such as bottlenose dolphins (Tursiops truncatus) can be impacted by large-scale mortality events due to exposure to marine algal toxins. In the Sarasota Bay region...Full Text Available

462

Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study  

UK PubMed Central (United Kingdom)

Partial epilepsies have a substantial heritability. However, the actual genetic causes are largely unknown. In contrast to many other common diseases for which genetic association-studies have successfully...Full Text Available

2010-07-01

463

Cold gas & mergers: fundamental difference in HI properties of different types of radio galaxies?  

CERN Document Server

We present results of a study of large-scale neutral hydrogen (HI) gas in nearby radio galaxies. We find that the early-type host galaxies of different types of radio sources (compact, FR-I and FR-II) appear to contain fundamentally different large-scale HI properties: enormous regular rotating disks and rings are present around the host galaxies of a significant fraction of low power compact radio sources, while no large-scale HI is detected in low power, edge-darkened FR-I radio galaxies. Preliminary results of a study of nearby powerful, edge-brightened FR-II radio galaxies show that these systems generally contain significant amounts of large-scale HI, often distributed in tail- or bridge-like structures, indicative of a recent galaxy merger or collision. Our results suggest that different types of radio galaxies may have a different formation history, which could be related to a difference in the ...

2008-01-01

464

Cloning and Nucleotide Sequence Determination of the Entire mec DNA of Pre-Methicillin-Resistant Staphylococcus aureus N315  

UK PubMed Central (United Kingdom)

In methicillin-resistant Staphylococcus aureus, the methicillin resistance gene mecA is localized within a large chromosomal region which is absent in the methicillin-susceptible...Full Text Available

1999-06-01

465

Centromere-encoded RNAs are integral components of the maize kinetochore  

UK PubMed Central (United Kingdom)

RNA is involved in a variety of chromatin modification events, ranging from large-scale structural rearrangements to subtle local affects. Here, we extend the evidence for RNA–chromatin interactions...Full Text Available

2004-11-09

466

Cecal Schwannoma: A Rare Cause of Gastrointestinal Bleeding in a Young Woman with Review of Literature  

UK PubMed Central (United Kingdom)

Schwannomas are rare mesenchymal tumors of the gastrointestinal tract. Occurrence of these tumors is more common in the stomach than in the large intestine. These tumors usually present as polypoidal...Full Text Available

2011-01-01

467

Cancer incidence and mortality in the Swedish polyurethane foam manufacturing industry.  

UK PubMed Central (United Kingdom)

Toluene diisocyanate (TDI) and methylene diphenyldiisocyanate (MDI) are used in large quantities in the polyurethane foam manufacturing industry. Both substances are mutagenic and at least TDI is carcinogenic...Full Text Available

1993-06-01

468

CHUQUICAMATA - The Gateway to Astronaut Photography of Earth  

Science.gov (United States)

ISS022, E, 8260, CHILE, CHUQUICAMATA, LARGE OPEN PIT MINING OPERATIONS, ROADS, HILLS, -22.3, -68.9, 20091209. ISS022, E, 8261, CHILE, CHUQUICAMATA, ...

469

Body mass index, waist circumference, and risk of coronary heart disease: a prospective study among men and women  

UK PubMed Central (United Kingdom)

ObjectiveThe purpose of the study was to assess the risk of CHD associated with excess weight measured by BMI and waist circumference (WC) in two large cohorts of...Full Text Available

2010-01-01

470

Biophysical characterization of recombinant proteins: A key to higher structural genomics success  

UK PubMed Central (United Kingdom)

Hundreds of genomes have been successfully sequenced to date, and the data are publicly available. At the same time, the advances in large-scale expression and purification of recombinant proteins have...Full Text Available

2010-10-01

471

Biodrying of animal slaughterhouse residues and heat production  

Energy Technology Data Exchange (ETDEWEB)

Animal carcasses from slaughterhouses are usually composted on farms, but the composting process is not optimized and a large volumes of carbonaceous residues are needed. This type of composting takes place over a period of 6 to 9 months in a nonaerated static pile. Quebec's industrial research centre (CRIQ) developed an organic biodrying process (BIOSECO) adapted to large-scale operations in order to optimize the treatment of slaughterhouse residues. Biodrying is a form of composting, in which the thermophilic phase is optimized, making it possible to evaporate large amounts of water. Biodrying is done inside a building and reduces the amount of carbonaceous residues considerably. The process is optimized by the sequence in which the slaughterhouse residues are added, the choice of input and the aeration flow. Slaughterhouse residues can be treated non-stop throughout the entire year. Since the odours are nearly ...

2010-07-01

472

Bathymetry and temperature of some glacial lakes in Wyoming  

UK PubMed Central (United Kingdom)

On the west flank of the Wind River Mountains, Wyoming, are several large lakes occupying glacially scoured depressions dammed by terminal moraines. Fremont, Willow, and New Fork Lakes, having maximal...Full Text Available

1980-04-01

473

Bacterial Artificial Chromosome Mutagenesis Using Recombineering  

UK PubMed Central (United Kingdom)

Gene expression from bacterial artificial chromosome (BAC) clones has been demonstrated to facilitate physiologically relevant levels compared to viral and nonviral cDNA vectors. BACs are large enough...Full Text Available

2011-01-01

474

BOOKMARKS:  

Wastenet

Secretariat of the Basel Convention United Nations Office at Geneva ...such as public utilities, waste disposal sites, large energy dependent facilities including factories, institutions (hospitals, ...it provides immediate identification of PCB wastes, informs company officials of any special handling or disposal techniques

475

BFL: a node and edge betweenness based fast layout algorithm for large scale networks  

UK PubMed Central (United Kingdom)

BackgroundNetwork visualization would serve as a useful first step for analysis. However, current graph layout algorithms for biological pathways are insensitive to biologically...Full Text Available

476

Automatic stenosis detection and quantification in renal arteriography.  

UK PubMed Central (United Kingdom)

Visual assessment of the degree of renal artery stenosis on renal arteriography has a large inter- and intraobserver variability. This degree is usually estimated by the ratio between the most narrowed...Full Text Available

1997-01-01

477

Antibacterial Colorants: Characterization of Prodiginines and Their Applications on Textile Materials  

UK PubMed Central (United Kingdom)

A strain of Vibrio sp. isolated from marine sediments produced large quantities of bright red pigments that could be used to dye many fibers including wool, nylon, acrylics,...Full Text Available

2008-05-01

478

Anomalous carbon isotope fractionation between atmospheric CO/sub 2/ and dissolved inorganic carbon induced by intense photosynthesis  

Energy Technology Data Exchange (ETDEWEB)

A stable isotope mass-balance of dissolved inorganic carbon during a blue-green algae bloom in a softwater lake demonstrates that at low partial pressure of carbon dioxide there must be a large net negative carbon isotope fractionation between atmospheric CO/sub 2/ and the CO/sub 2/ absorbed by lake water at pH = 9.5. Chemical enhancement of CO/sub 2/ invasion at high pH by the reaction CO/sub 2/ + OH/sup -/ ..-->.. HCO/sub 3//sup -/ at large apparent film thicknesses may result in carbon isotope fractionation approaching that for a hydroxide solution. This phenomenon, coupled with a decrease in the photosynthetic fractionation, forced the surface water of a softwater lake to achieve increasingly negative delta /sup 13/C values during an algal bloom, which is in the opposite sense to the trend that results from photosynthesis under less extreme conditions. This and other similar systems must operate under non-equilibrium (kinetic) ...

1987-04-01

479

Analyzing the simplicial decomposition of spatial protein structures  

UK PubMed Central (United Kingdom)

BackgroundThe fast growing Protein Data Bank contains the three-dimensional description of more than 45000 protein- and nucleic-acid structures today. The large majority of the data...Full Text Available

480

An outbreak of illness among aerospace workers.  

UK PubMed Central (United Kingdom)

A multispecialty panel of physicians evaluated a case series of 53 composite-materials workers in a large aircraft manufacturing facility who filed workers' compensation claims for illness labeled by...Full Text Available

1990-07-01

481

An analysis by low-angle neutron scattering of the structure of the acetylcholine receptor from Torpedo californica in detergent solution.  

UK PubMed Central (United Kingdom)

The acetylcholine receptor from the electric tissue of Torpedo californica is a large, integral membrane protein containing four different types of polypeptide chains. The structure of the purified...Full Text Available

1979-12-01

482

Alleged Mycotoxicosis in Swine: Review of a Court Case  

UK PubMed Central (United Kingdom)

Vomition and diarrhea in feeder pigs, and signs of hyperestrogenism in sows and pregnant gilts in a large swine operation were thought to be caused by mycotoxins. Various toxicoanalytical tests performed...Full Text Available

1981-05-01

483

Algebraic Structure of Linear Dynamical Systems. III. Realization Theory Over a Commutative Ring  

UK PubMed Central (United Kingdom)

The realization theory linear dynamical systems, previously developed over a field, are extended to a large class of commutative rings. The principal result is that the existence criterion for a finite...Full Text Available

1972-11-01

484

Advances in cancer tissue microarray technology: Towards improved understanding and diagnostics  

UK PubMed Central (United Kingdom)

Over the past few years, tissue microarray (TMA) technology has been established as a standard method for assessing the expression of proteins or genes across large sets of tissue specimens....Full Text Available

2006-03-30

485

Adult Morgagni Hernia: The Need for Clinical Awareness, Early Diagnosis and Prompt Surgical Intervention  

UK PubMed Central (United Kingdom)

We report an unusual case of strangulated diaphragmatic (Morgagni) hernia resulting in ischaemia of the small and large bowel, which was initially diagnosed as a pneumonia. This case highlights the...Full Text Available

2008-11-01

486

Active magnetic regenerator  

Energy Technology Data Exchange (ETDEWEB)

The disclosure is directed to an active magnetic regenerator apparatus and method. Brayton, Stirling, Ericsson, and Carnot cycles and the like may be utilized in an active magnetic regenerator to provide efficient refrigeration over relatively large temperature ranges.

1982-01-01

487

Acetylene Reduction by Soil Cores of Maize and Sorghum in Brazil  

UK PubMed Central (United Kingdom)

Nitrogenase activity was measured by the C2H2 reduction method in large soil cores (29 cm in diameter by 20 cm in depth) of maize (Zea mays) and sorghum (Sorghum...Full Text Available

1977-03-01

488

Access Intervention in an Integrated, Prepaid Group Practice: Effects on Primary Care Physician Productivity  

UK PubMed Central (United Kingdom)

ObjectiveTo estimate the joint effect of a multifaceted access intervention on primary care physician (PCP) productivity in a large, integrated prepaid group practice.Data...Full Text Available

2008-10-01

489

A self-oscillating biophysical computer model of the elongated vocal fold  

UK PubMed Central (United Kingdom)

A new 3D model is developed to simulate the self-oscillation of the elongated vocal folds. This model allows for large deformation and longitudinal displacement. The displacement boundary condition...Full Text Available

2008-01-01

490

A multistep bioinformatic approach detects putative regulatory elements in gene promoters  

UK PubMed Central (United Kingdom)

BackgroundSearching for approximate patterns in large promoter sequences frequently produces an exceedingly high numbers of results. Our aim was to exploit biological knowledge for...Full Text Available

491

A look back at Minexpo  

Energy Technology Data Exchange (ETDEWEB)

This paper reviews some of the mining equipment exhibited at the Chicago Minexpo exhibition. The exhibits include: large mining trucks; tractor with impact ripper; haulers; shuttle roof bolter; and monitoring systems for vehicles or mining machines. 2 figs.

1988-07-01

492

A haplotype map of the human genome  

UK PubMed Central (United Kingdom)

Inherited genetic variation has a critical but as yet largely uncharacterized role in human disease. Here we report a public database of common variation in the human genome: more than one million...Full Text Available

2005-10-27

493

A genome-wide survey of Major Histocompatibility Complex (MHC) genes and their paralogues in zebrafish  

UK PubMed Central (United Kingdom)

BackgroundThe genomic organisation of the Major Histocompatibility Complex (MHC) varies greatly between different vertebrates. In mammals, the classical MHC consists of a large number...Full Text Available

494

A cross-sectional study of Tritrichomonas foetus infection among healthy cats at shows in Norway  

UK PubMed Central (United Kingdom)

BackgroundIn recent years, the protozoan Tritrichomonas foetus has been recognised as an important cause of chronic large-bowel diarrhoea in purebred cats in many...Full Text Available

495

A Multi-Worksite Analysis of the Relationships among Body Mass Index, Medical Utilization and Worker Productivity  

UK PubMed Central (United Kingdom)

BackgroundThe relationships between worker health and productivity are becoming clearer. However, few large scale studies have measured the direct and indirect cost...Full Text Available

2010-01-01

496

A Marker-Dense Physical Map of the Bradyrhizobium japonicum Genome  

UK PubMed Central (United Kingdom)

Bacterial artificial chromosome (BAC) clones are effective mapping and sequencing reagents for use with a wide variety of small and large genomes. This report describes the development of a physical...Full Text Available

2001-08-01

497

A Large-Scale Distribution of Milk-Based Fortified Spreads: Evidence for a New Approach in Regions with High Burden of Acute Malnutrition  

UK PubMed Central (United Kingdom)

BackgroundThere are 146 million underweight children in the developing world, which contribute to up to half of the world's child deaths. In high burden regions for malnutrition,...Full Text Available

498

A DNA transposon-based approach to validate oncogenic mutations in the mouse  

UK PubMed Central (United Kingdom)

Large-scale cancer genome projects will soon be able to sequence many cancer genomes to comprehensively identify genetic changes in human cancer. Genome-wide association studies have also identified...Full Text Available

2008-12-16

499

17 FEB 1998 - NASA Office of Inspector General  

Science.gov (United States)

(General Stafford) was selected as chair for the Task Force based on his expertise .... a large foreign customer base that includes joint working agreements with Russia, the .... NASA Headquarters management advocates the Jorge Scientific ...

500

14 - NASA  

Science.gov (United States)

... and mean rainfall rates, Rm, in the liquid hydrometeor layers using the .... large latitudinal movement of cirrus cloud cover with the changing seasons. ... We study the statistical distribution of PSCs by particle composition using .... the high resolution Cloud Particle Imager (CPI) and standard PMS 2D-C and ...