WorldWideScience
 
 
1

A new measurement method for spine reposition sense  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Abstract Background A cost effective tool for the measurement of trunk reposition sense is needed clinically. This study evaluates the reliability and validity of a new clinical spine reposition sense device. Methods The first part of this three part investigation included 45 asymptomatic subjects examined in the first 20 repeated trials portion assessing spine reposition sense. The second portion, test-retest, examined 57 asymptomatic subjects. Initial testing ...

Petersen Cheryl M; Zimmermann Chris L; Cope Steven; Bulow Mary; Ewers-Panveno Erinn

2008-01-01

2

Validation of spinal motion with the spine reposition sense device  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background A sagittal plane spine reposition sense device (SRSD has been developed. Two questions were addressed with this study concerning the new SRSD: 1 whether spine movement was occurring with the methodology, and 2 where movement was taking place. Methods Sixty-five subjects performed seven trials of repositioning to a two-thirds full flexion position in sitting with X and Y displacement measurements taken at the T4 and L3 levels. The thoracolumbar angle between the T4 and the L3 level was computed and compared between the positions tested. A two (vertebral level of thoracic and lumbar by seven (trials mixed model repeated measures ANOVA indicated whether significant differences were present between the thoracic (T4 and lumbar (L3 angular measurements. Results Calculated thoracolumbar angles between T4 and L3 were significantly different for all positions tested indicating spinal movement was occurring with testing. No interactions were found between the seven trials and the two vertebral levels. No significant findings were found between the seven trials but significant differences were found between the two vertebral levels. Conclusion This study indicated spine motion was taking place with the SRSD methodology and movement was found specific to the lumbar spine. These findings support utilizing the SRSD to evaluate changes in spine reposition sense during future intervention studies dealing with low back pain.

Rundquist Peter J

2009-04-01

3

A new measurement method for spine reposition sense  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background A cost effective tool for the measurement of trunk reposition sense is needed clinically. This study evaluates the reliability and validity of a new clinical spine reposition sense device. Methods The first part of this three part investigation included 45 asymptomatic subjects examined in the first 20 repeated trials portion assessing spine reposition sense. The second portion, test-retest, examined 57 asymptomatic subjects. Initial testing consisted of subjects sitting on the device and performing 20 trials of a self-determined 2/3 trunk flexion position. The second portion of the study involved 7 trials of trunk flexion performed twice. The angular position for each trial was calculated and the mean reposition error from the initial 2/3 position was determined. For the third portion, the new device was compared to the Skill Technologies 6D (ST6D Imperial Motion Capture and Analysis System. Results ICC (3,1 for trials 4–7 was 0.79 and 0.76 for time one and time two, respectively and the test-retest ICC (3,k was 0.38. Due to the poor test-retest ICC, the Bland Altman method was used to compare test and retest absolute errors. Most measurement differences were small and fell within the 95% confidence interval. Comparable measures between the two methods were found using the Bland Altman method to compare the reposition sense device to the ST6D system. Conclusion The device may be a cost effective clinical technique for sagittal trunk reposition sense measurement.

Cope Steven

2008-03-01

4

Repositioning of the caudal septal dislocations with notching and suturing the cartilage to the nasal spine.  

Science.gov (United States)

We aim to define a cartilage reshaping and repositioning technique for caudal septal dislocations, with the logic of adapting the smoother tissues to the stiffer structures. The study was designed retrospectively with the patient charts and photographic analysis. Thirty-six patients who had septal surgery in a septoplasty or an open approach septorhinoplasty operation and meet the inclusion criteria were evaluated for the study. Postoperative success of the technique was based on preoperative and postoperative photographic analysis by two independent otorhinolaryngologists. The estimators classified 33 cases as near complete, 3 cases as improved but persisting caudal septal deviation, and any cases with no change. The improvement of the degree of reconstruction was near complete about 87% in septoplasty and 95% in septorhinoplasty groups, and 92% for all patients. In this study, we present a caudal septal repositioning maneuver which achieves a stable anchorage between postero-caudal septal cartilage and nasal spine. Septal cartilage is notched and fixed to nasal spine with two simple independent sutures as lock and key model. We define this maneuver as riding spine technique. It is an anatomic re-orientation between the septum and nasal spine for caudal septal deviations and subluxations. PMID:23543300

Akduman, Davut; Haksever, Mehmet; Yanilmaz, Muhammed

2014-01-01

5

Liner Shipping Fleet Repositioning  

DEFF Research Database (Denmark)

Liner shipping fleet repositioning consists of moving vessels between services in a liner ship- ping network in order to better orient the overall network to the world economy, and to ensure the proper maintenance of vessels. Thus, fleet repositioning involves sailing and loading activities subject to complex handling and timing restrictions. The objective of the problem is cost minimization, which translates nearly directly into the minimization of CO2 emissions and pollution. Additionally, it is important that all cost elements, including the ones that are only loosely coupled with activity choices, can be accurately modeled. Numerous liner shipping fleet repositioning problems are solved each year by the worldâ??s shipping firms without the assistance of any decision support, even though humans can require between two to three days to find a reasonable solution. Finding optimal repositionings is important in helping shipping firms move towards their goal of greater eco-efficiency.

Tierney, Kevin; Jensen, Rune Møller

6

STRATEGICALLY REPOSITIONING RUSSIA  

Directory of Open Access Journals (Sweden)

Full Text Available Positioning is a very important marketing concept. Its importance was strongly emphasized and implemented in the case of companies, but is somehow neglected when it comes to states. A country acquires a position in the mind of a person very much like any other product does, which is very important especially when that person exerts an executive role. Nowadays Russia has a poor image or no image at all, both internationally and in Romania. In order to regain an important position in the Balkans region, Russia must set aside any political agenda and reposition itself as a business partner on equal terms. The first goal of this article is to clarify Russias position in the minds of future Romanian executives. The second goal is to outline a recommended course of actions for Russias repositioning.

Brandabur Raluca Ecaterina

2011-07-01

7

Centromere repositioning in mammals  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The evolutionary history of chromosomes can be tracked by the comparative hybridization of large panels of bacterial artificial chromosome clones. This approach has disclosed an unprecedented phenomenon: ‘centromere repositioning', that is, the movement of the centromere along the chromosome without marker order variation. The occurrence of evolutionary new centromeres (ENCs) is relatively frequent. In macaque, for instance, 9 out of 20 autosomal centromeres are evolutionarily new; in donke...

Rocchi, M.; Archidiacono, N.; Schempp, W.; Capozzi, O.; Stanyon, R.

2012-01-01

8

Drug repositioning for personalized medicine  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Human diseases can be caused by complex mechanisms involving aberrations in numerous proteins and pathways. With recent advances in genomics, elucidating the molecular basis of disease on a personalized level has become an attainable goal. In many cases, relevant molecular targets will be identified for which approved drugs already exist, and the potential repositioning of these drugs to a new indication can be investigated. Repositioning is an accelerated route for drug discovery because exi...

Li, Yvonne Y.; Jones, Steven Jm

2012-01-01

9

Nucleosome repositioning via loop formation  

CERN Multimedia

Active (catalysed) and passive (intrinsic) nucleosome repositioning is known to be a crucial event during the transcriptional activation of certain eucaryotic genes. Here we consider theoretically the intrinsic mechanism and study in detail the energetics and dynamics of DNA-loop-mediated nucleosome repositioning, as previously proposed by Schiessel et al. (H. Schiessel, J. Widom, R. F. Bruinsma, and W. M. Gelbart. 2001. {\\it Phys. Rev. Lett.} 86:4414-4417). The surprising outcome of the present study is the inherent nonlocality of nucleosome motion within this model -- being a direct physical consequence of the loop mechanism. On long enough DNA templates the longer jumps dominate over the previously predicted local motion, a fact that contrasts simple diffusive mechanisms considered before. The possible experimental outcome resulting from the considered mechanism is predicted, discussed and compared to existing experimental findings.

Kulic, M L

2002-01-01

10

Transfemoral Repositioning of Malpositioned Central Venous Catheters  

International Nuclear Information System (INIS)

Purpose: To determine the efficacy of the transfemoral vein approach to repositioning malpositioned central venous catheters. Methods: During a 41/2-year period, malpositioned central venous catheters were repositioned 91 times in 83 patients via the transfemoral vein approach. All repositioning was initially attempted with a Grollman catheter or other pigtail catheter and a tip-deflecting wire. If these techniques failed or the venous anatomy was unfavorable, gooseneck or long loop snares were used. Results: During 48 repositionings, rotating a pigtail-type catheter alone was used successfully in 39 (81%). In 6 of 9 failures, the addition of a tip-deflecting wire also failed. A Grollman catheter and tip-deflecting wire were used initially in 39 repositionings (6 failures; 85% success). Successful repositioning required a snare in 8 (4 as the primary repositioning technique) and a long-loop technique in 5. All repositionings were ultimately successful and there were no complications. Conclusion: Central venous catheters can be repositioned consistently by the transfemoral route. Pigtail catheters or tip-deflecting wires alone are successful in over 80% of cases

1996-09-01

11

Skeletal stability after inferior maxillary repositioning without interpositional graft.  

Science.gov (United States)

True vertical maxillary deficiency is a characteristic of short face syndrome. In these patients, inferior repositioning of the maxilla (IRM) is indicated to improve facial aesthetics and function, but this procedure has been described as the most unstable. The aim of this study was to evaluate the long term, post surgical stability of IRM, fixed with four 2.0mm L-shaped miniplates, without any type of graft. A cephalometric study was performed, analysing linear measurements (anterior nasal spine, the A point, top of the incisor, top of the buccal-mesial cusp of the first molar, and posterior nasal spine on an X-Y coordinate system) traced immediately preoperatively, immediately postoperatively and at least 6 months post operatively. Eight young adult patients who underwent IRM were studied. The average results of this study were: surgical movement of 4.65 mm at I point, 5.32 mm at anterior nasal spine (ANS) point, and 4.70 mm at A point and relapses of 1.60 mm (35%), 2.23 mm (43%) and 2.10 mm (46%), respectively. It was concluded, that IRM using this type of internal rigid fixation without graft is unstable. PMID:22192387

Santos, S E; Moreira, R W F; de Moraes, M; Asprino, L; Araujo, M M

2012-04-01

12

Repositioning of Covered Stents: The Grip Technique  

International Nuclear Information System (INIS)

Introduction: Retrieval and repositioning of a stent deployed beyond its intended target region may be a difficult technical challenge. Materials and Methods: A balloon-mounted snare technique, a variant of the coaxial loop snare technique, is described. Results: The technique is described for the repositioning of a covered transjugular intrahepatic portosystemic shunt stent and a covered biliary stent. Conclusion: The balloon-mounted snare technique is a useful technique for retrieval of migrated stents.

2011-06-01

13

Osteoporosis and Your Spine  

Science.gov (United States)

... Home » Osteoporosis and Your Spine Osteoporosis and Your Spine Your spine is made up of small bones ... called kyphosis. Kyphosis and Bone Breaks in the Spine The bones in the spine are called vertebrae. ...

14

Temporal Optimization Planning for Fleet Repositioning  

DEFF Research Database (Denmark)

Fleet repositioning problems pose a high financial bur- den on shipping firms, but have received little attention in the literature, despite their high importance to the shipping industry. Fleet repositioning problems are characterized by chains of interacting activities, but state-of-the-art planning and scheduling techniques do not offer cost models that are rich enough to represent essential objectives of these problems. To this end, we introduce a novel framework called Temporal Optimization Planning (TOP). TOP uses partial order planning to build optimization models associated with the different possible activity scenarios and applies branch-and-bound with tight lower bounds to find optimal solutions efficiently. We show how key aspects of fleet repositioning can be modeled using TOP and demonstrate experimentally that our approach scales to the size of problems considered by our industrial collaborators.

Tierney, Kevin; Jensen, Rune Møller

15

Percutaneous Repositioning of dislodged atrial pacing lead  

Directory of Open Access Journals (Sweden)

Full Text Available The overall rate of atrial pacing lead dislodgement is estimated to be about 3%. These leads are generally repositioned via a second operation through opening the pacemaker pocket.Some operators have introduced percutaneous techniques using snare system or deflectable catheters for this purpose.In this article we present our experience with five cases of percutaneous lead repositioning. Three cases were performed using deflectable ablation catheters and in two cases we used a specially designed urologic basket. The procedural success rate was 100% at the beginning but the long term success rate was 60%.

Ali Kazemi saeid

2006-07-01

16

Lumbar spine CT scan  

Science.gov (United States)

CAT scan - lumbar spine; Computed axial tomography scan - lumbar spine; Computed tomography scan - lumbar spine; CT - lower back ... stopping.) A computer creates separate images of the spine area, called slices. These images can be stored, ...

17

DNA bending potentials for loop-mediated nucleosome repositioning  

Energy Technology Data Exchange (ETDEWEB)

Nucleosome repositioning is a fundamental process in gene function. DNA elasticity is a key element of loop-mediated nucleosome repositioning. Two analytical models for DNA elasticity have been proposed: the linear sub-elastic chain (SEC), which allows DNA kinking, and the worm-like chain (WLC), with a harmonic bending potential. In vitro studies have shown that nucleosomes reposition in a discontiguous manner on a segment of DNA and this has also been found in ground-state calculations with the WLC analytical model. Here we study using Monte Carlo simulation the dynamics of DNA loop-mediated nucleosome repositioning at physiological temperatures using the SEC and WLC potentials. At thermal energies both models predict nearest-neighbor repositioning of nucleosomes on DNA, in contrast to the repositioning in jumps observed in experiments. This suggests a crucial role of DNA sequence in nucleosome repositioning.

Langowski, Jorg [German Cancer Research Center, Heidelberg

2012-01-01

18

Automated Planning for Liner Shipping Fleet Repositioning.  

DEFF Research Database (Denmark)

The Liner Shipping Fleet Repositioning Problem (LSFRP) poses a large financial burden on liner shipping firms. During repositioning, vessels are moved between services in a liner shipping network. The LSFRP is characterized by chains of interacting activities, many of which have costs that are a function of their duration; for example, sailing slowly between two ports is cheaper than sailing quickly. Despite its great industrial importance, the LSFRP has received little attention in the literature. We show how the LSFRP can be solved sub-optimally using the planner POPF and optimally with a mixed-integer program (MIP) and a novel method called Temporal Optimization Planning (TOP). We evaluate the performance of each of these techniques on a dataset of real-world instances from our industrial collaborator, and show that automated planning scales to the size of problems faced by industry.

Tierney, Kevin; Jensen, Rune Møller

2012-01-01

19

Computer-assisted posterior instrumentation of the cervical and cervico-thoracic spine  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Posterior instrumentation of the cervical spine has become increasingly popular in recent years. Dissatisfaction with lateral mass fixation, especially at the cervico-thoracic junction, has led spine surgeons to use pedicle screws. The improved biomechanical stability of pedicle screws and transarticular C1/2 screws allows for shorter instrumentations and improves the repositioning possibilities. Nevertheless, there are potential risks of iatrogenic damage to the spinal cord, nerve roots or t...

Richter, Marcus; Mattes, Thomas; Cakir, Balkan

2004-01-01

20

Protecting Your Fragile Spine  

Science.gov (United States)

Protecting Your Fragile Spine Table of Contents PROTECTING YOUR FRAGILE SPINE 1 Osteoporosis basics .........................................................................2 Are you at risk ..................................................................................3 Broken bones in the spine ..............................................................3 Signs and symptoms of broken bones in ...

 
 
 
 
21

Sisyphi Spine  

Science.gov (United States)

26 June 2006 This Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows a spine of material exposed in the Sisyphi Planum region of Mars. Gullies can be seen on the deeply-shadowed ridge slope. Mass movement (landsliding) has contributed to the erosion of this ridge and the creation of the apron of talus that surrounds it. Location near: 70.7oS, 357.0oW Image width: 3 km (1.9 mi) Illumination from: upper left Season: Southern Summer

2006-01-01

22

Optimizing Liner Shipping Fleet Repositioning Plans  

DEFF Research Database (Denmark)

With the incredible growth of containerization over the past half century, shipping lines and ports are facing increasing challenges in ensuring that containers arrive at their destinations on time and on budget. This dissertation addresses several critical problems to the operations of shipping lines and ports, and provides algorithms and mathematical models for use by shipping lines and port authorities for decision support. One of these problems is the repositioning of container ships in a liner shipping network in order to adjust the network to seasonal shifts in demand or changes in the world economy. We provide the rst problem description and mathematical model of repositioning and dene the liner shipping eet repositioning problem (LSFRP). The LSFRP is characterized by chains of interacting activities with a multi-commodity ow over paths dened by the activities chosen. We rst model the problem without cargo ows with a variety of well-known optimization techniques, as well as using a novel method called linear temporal optimization planning that combines linear programming with partial-order planning in a branch-and-bound framework. We then model the LSFRP with cargo ows, using several dierent mathematical models as well as two heuristic approaches. We evaluate our techniques on a real-world dataset that includes a scenario from our industrial collaborator. We show that our approaches scale to the size of problems faced by industry, and are also able to improve the prot on the reference scenario by over US$14 million. This dissertation also addresses the topic of inter-terminal transportation (ITT), which involves minimizing the delay experienced by containers being transported between terminals in a port under varying infrastructure congurations and material handling equipment properties. Minimizing the delay of ITT is an important problem in the strategic planning of new ports and port expansions, and one that has not yet been addressed in an optimization based approach. We provide the rst mathematical model of ITT and show how the model can be used to provide critical information to port authorities on two real ports, the port of Hamburg, Germany, and the Maasvlakte area of the port of Rotterdam, Netherlands. Finally, this thesis gives a polynomial time algorithm for an open problem from the container stowage literature, the capacitated k-shift problem with a xed number of stacks and stack heights, providing an answer to a 13 year old theoretical question in the container stowage domain.

Tierney, Kevin

2013-01-01

23

An innovative cosmetic technique called lip repositioning  

Directory of Open Access Journals (Sweden)

Full Text Available A clinical report describing the successful use of the lip repositioning technique for the reduction of excessive gingival display. A female patient aged 34 years reported with a chief complaint of gummy smile and was treated with this technique performed under local anesthesia with the main objective to reduce gummy smile by limiting the retraction of elevator muscles (e.g., zygomaticus minor, levator anguli, orbicularis oris, and levator labii superioris. The technique is fulfilled by removing a strip of mucosa from maxillary buccal vestibule and creating a partial thickness flap between mucogingival junction and upperlip musculature, and suturing the lip mucosa with mucogingival junction, resulting in a narrow vestibule and restricted muscle pull, thereby reducing gingival display.

Gupta Krishna

2010-01-01

24

Dual cervical thoracic coil for spine magnetic resonance imaging  

International Nuclear Information System (INIS)

The need for repositioning of surface coils and patients in MR examinations of the cervical and thoracic spin prolongs examination time. A new receiver design is proposed which overcomes this problem. The device is composed of two actively decoupled receiver coils mounted on the frame of a Philadelphia collar. These coils may be used separately to image either the thoracic or cervical spine or together to produce larger field-of-view images of the combined region. Signal-to-noise ratios of the separate cervical and thoracic spine images are not degraded as a result of mounting the receivers together. The full cervical and thoracic region is shown to be imaged at a signal-to-noise ratio significantly higher than that afforded by the body coil. A retrospective review of our case load suggests that a time saving could be achieved in approximately 1/3 of spine examinations by using this coil. (orig.)

1989-01-01

25

The spine  

International Nuclear Information System (INIS)

High-resolution magnetic resonance imaging (MRI) of the spine promises to replace all other imaging modalities including plain films, computed tomography (CT), and myelography, in most disorders affecting the cord or canal. Stringent objective criteria of high-quality, high-resolution images have not been firmly established. Critical components revolve about optimization of signal to noise (S/N), good contrast, and good edge definition, the latter representing an important component of spatial detail. Signal-to-noise ratio is influenced by gradient coils, power supplies, preamps, fringe fields, eddy currents, software, etc.;and S/N also increases linearly with increasing field strength. A three- to five-fold increase in S/N can be achieved with surface receiving coils. Surface coils must be designed so that they are appropriate in size and impedance for the object being imaged and the size and weight of the patient. Depth resolution of surface coils is defined by the radius of the coil

1987-01-01

26

Spine Injuries and Disorders  

Science.gov (United States)

Your backbone, or spine, is made up of 26 bone discs called vertebrae. The vertebrae protect your spinal cord and allow you to ... of problems can change the structure of the spine or damage the vertebrae and surrounding tissue. They ...

27

North American Spine Society  

Science.gov (United States)

... Final Programs Future Events Attend the world's largest spine meeting and exhibition! This is truly a one- ... FELLOWSHIP TRAINING DIRECTORY VIEW PRESENTATIONS Publications Publications The Spine Journal Browse Journals Editorial Board Author Instructions Reviewer ...

28

Case report: Non-operative repositioning and fixation of a fractured calcaneum in the operating theater; Fallstudie: Unblutige Reposition und Fixierung einer Fersenbeinfraktur im OP  

Energy Technology Data Exchange (ETDEWEB)

Using the mobile CT system Tomoscan M for non-operational repositioning and fixation of a fractured calcineum reduces the risk of infection and achieves anatomically exact and correct repositioning. (orig./CB) [German] Der Einsatz eines mobilen CT-Systems Tomoscan M bei der unblutigen Reposition und Fixierung einer Fersenbeinfraktur senkt das Infektionsrisiko und sorgt fuer eine exakte anatomische Repositionierung. Eine Fallstudie. (orig.)

Haeuser, H. [Zentralklinikum Augsburg (Germany). Klinik fuer Diagnostische Radiologie und Neuroradiologie

2000-05-01

29

The Liner Shipping Fleet Repositioning Problem with Cargo Flows  

DEFF Research Database (Denmark)

We solve an important problem for the liner shipping industry called the Liner Shipping Fleet Repositioning Problem (LSFRP). The LSFRP poses a large financial burden on liner shipping firms. During repositioning, vessels are moved between services in a liner shipping network. Shippers wish to reposition vessels as cheaply as possible without disrupting the cargo flows of the network. The LSFRP is characterized by chains of interacting activities with a multi-commodity flow over paths defined by the activities chosen. Despite its great industrial importance, the LSFRP has received little attention in the literature. We introduce a novel mathematical model of the LSFRP with cargo flows based on a carefully constructed graph and evaluate it on real world data from our industrial collaborator.

Tierney, Kevin; Jensen, Rune Møller

2012-01-01

30

CAMIF, an SME Repositioning Its Line as Sustainable Development Products  

Directory of Open Access Journals (Sweden)

Full Text Available The purpose of this article is to review the application of Sustainable Development (SD in the marketing strategies of French firms, and to show how one SME, CAMIF, has repositioned its product line around SD. Although SD policies in France are now driven by rising demands from lawmakers and consumers alike, their application has not yet become a central feature of the strategies of major companies and SMEs. In this regard, the innovative repositioning of CAMIF around fair and responsible value is found to be consistent with the firm’s values, and permeates its marketing mix.

Bénédicte Bourcier-Bequaert

2012-06-01

31

A PDDL Domain for the Liner Shipping Fleet Repositioning Problem  

DEFF Research Database (Denmark)

The Liner Shipping Fleet Repositioning Problem (LSFRP) poses a large financial burden on liner shipping firms. During repositioning, vessels are moved between services in a liner shipping network. The LSFRP is characterized by chains of interacting activities, many of which have costs that are a function of their duration; for example, sailing slowly between two ports is cheaper than sailing quickly. Despite its great industrial importance, the LSFRP has received little attention in the literature. We model the LSFRP using PDDL and solve it using the planner.

Tierney, Kevin; Coles, Amanda

2012-01-01

32

Repositioning and follow-up of intralenticular dexamethasone implant.  

Science.gov (United States)

We report the case of a 54-year-old man who attended our emergency department complaining of severe floaters and decreased vision in his right eye. Seven days earlier, a dexamethasone intravitreal implant (Oxurdex) had been placed for a noninfectious posterior uveitis. Slitlamp examination showed the implant had penetrated the posterior lens capsule and was lodged in the posterior cortex of the lens; a posterior cortical cataract developed subsequently. Removal of the cataract, repositioning of the implant to the posterior segment, and the postoperative course are described. To our knowledge, this is the first report of the repositioning of an intralenticular dexamethasone intravitreal implant. PMID:23889870

Munteanu, Mihnea; Rosca, Cosmin

2013-08-01

33

Repositioning of Pedicle Conjunctival Flap Performed for Refractory Corneal Ulcer  

Science.gov (United States)

A 50-year-old male was referred with a previous history of conjunctival flap (CF) for a nonhealing fungal corneal ulcer with extreme corneal thinning in the right eye. The peritomy for the CF extended from 6:30 to 9:30 clock h on the cornea. The CF was disengaged, peritomy area deepithelialized, and CF was repositioned. He later underwent penetrating keratoplasty and achieved 20/40 best corrected visual acuity. The authors present a new concept for surgically repositioning CF s to the original site immediately after healing of the corneal ulcer.

Sharma, Ashok; Mohan, Kanwar; Sharma, Rajan; Nirankari, Verinder S.

2014-01-01

34

Cactus spine injuries.  

Science.gov (United States)

Cactus spines produce injuries whose clinical significance is loosely in inverse proportion to the dimensions of the spine. Long and medium spines of saguaro and barrel cacti seldom result in embedded fragments, but when they do they are difficult to locate and remove. Other medium spines, those of prickly pear and cholla, are a nuisance but they can be removed readily by traction, as can the smaller spines (glochids) of the prickly pear. The very small spines (also glochids) of the polka dot or bunny's ear cactus (Opuntia microdasys) and the beavertail cactus (Opuntia basilaris) offer the most frustrating problem of all, but can be peeled off with a dried film of a professional facial gel. PMID:3390256

Lindsey, D; Lindsey, W E

1988-07-01

35

Case report: Non-operative repositioning and fixation of a fractured calcaneum in the operating theater  

International Nuclear Information System (INIS)

Using the mobile CT system Tomoscan M for non-operational repositioning and fixation of a fractured calcineum reduces the risk of infection and achieves anatomically exact and correct repositioning. (orig./CB)

2000-05-01

36

Cervical Spine Axial Rotation Goniometer Design  

Directory of Open Access Journals (Sweden)

Full Text Available To evaluate the cervical spine rotation movement is quiet harder than other joints. Configuration and arrangement of current goniometers and devices is not always practic in clinics and some methods are quiet expensive. The cervical axial rotation goniometer designed by the authors is consists of five pieces (head apparatus, chair, goniometric platform, eye pads and camera. With this goniometer design a detailed evaluation of cervical spine range of motion can be obtained. Besides, measurement of "joint position sense" which is recently has rising interest in researches can be made practically with this goniometer.

Emin Ula? Erdem

2012-06-01

37

Laryngeal dislocation after ventral fusion of the cervical spine.  

Science.gov (United States)

We report on a 70-year-old patient who underwent ventral fusion of the cervical spine (C3/4 and C4/5) for spinal canal stenosis performed by the neurosurgery department. The patient suffered an exceedingly rare complication of the surgery - laryngeal dislocation. Had the deformed laryngeal structures been overlooked and the patient extubated as usual after surgery, reintubation would have been impossible due to the associated swelling, which might have had disastrous consequences. Leftward dislocation of the larynx became apparent post-operatively, but prior to extubation. Extubation was therefore postponed and a subsequent computed tomography (CT) scan revealed entrapment of laryngeal structures within the osteosynthesis. A trial of repositioning using microlaryngoscopy performed by otolaryngology (ears, nose and throat) specialists failed, making open surgical revision necessary. At surgery, the entrapped laryngeal tissue was successfully mobilised. Laryngeal oedema developed despite prompt repositioning; thus, necessitating tracheotomy and long-term ventilation. Laryngeal dislocation may be an unusual cause of post-operative neck swelling after anterior cervical spine surgery and should be considered in the differential diagnosis if surgical site haematoma and other causes have been ruled out. Imaging studies including CT of the neck may be needed before extubation to confirm the suspicion and should be promptly obtained to facilitate specific treatment. PMID:23983289

Krauel, Jenny; Winkler, Dietrich; Münscher, Adrian; Tank, Sascha

2013-05-01

38

Solving The Liner Shipping Fleet Repositioning Problem with Cargo Flows  

DEFF Research Database (Denmark)

We solve a central problem in the liner shipping industry called the Liner Shipping Fleet Repositioning Problem (LSFRP). The LSFRP poses a large financial burden on liner shipping firms. During repositioning, vessels are moved between routes in a liner shipping network. Shippers wish to reposition vessels as cheaply as possible without disrupting the cargo flows of the network. The LSFRP is characterized by chains of interacting activities with a multi-commodity flow over paths defined by the activities chosen. Despite its industrial importance, the LSFRP has received little attention in the literature. We introduce a novel mathematical model and a simulated annealing algorithm of the LSFRP with cargo flows that makes use of a carefully constructed graph and evaluate them on real world data from our industrial collaborator. Additionally, we compare our approach's performance against an actual repositioning scenario, one of many undertaken by our industrial collaborator in 2011, in which our simulated annealing algorithm is able to double the profit earned in our industrial collaborator's solution to $15.5 million dollars using only few minutes of CPU time, showing that our algorithm could be used in a decision support system to solve the LSFRP.

Tierney, Kevin; Áskelsdóttir, Björg

2013-01-01

39

Anesthesia for Spine Surgery  

Directory of Open Access Journals (Sweden)

Full Text Available Patient presenting for surgical procedures of the spine are a diverse population undergoing a wide variety of operative procedures and present diverse challenge to the anesthesiologists. The anesthetic management depends on the operative site; spine pathology; surgical approach and the anesthesiologists experience & expertise.

Dr. Aloka Samantaray

2006-01-01

40

Lumbosacral spine x-ray  

Science.gov (United States)

X-ray - lumbosacral spine; X-ray - lower spine ... be placed over the lower part of your spine. You will be asked to hold your breath ... x-ray. The most common reason for lumbosacral spine x-ray is to look for the cause ...

 
 
 
 
41

Spine and sport.  

Science.gov (United States)

The spine, in athletes is a relatively frequent origin of problems. Chronic spine problems are much more common compared to acute injuries. Chronic injuries to the spine most often occur in low-contact sports like gymnastics and are most commonly the result of overuse. Acute injuries are more common in high-speed and full contact sports and are traumatic in origin. Injuries to the spinal cord can be devastating but are fortunately very uncommon. Although imaging of the spine appears to be straightforward, any radiologist will acknowledge that the optimal imaging strategy is often unclear due to several reasons. For the cervical spine much has improved since the NEXUS and CCR studies appeared in which clear rules were defined when to image the C-spine in acute trauma situations. For the thoracic and lumbar spines such rules are not defined. Although conventional imaging has long been the primary imaging modality of choice there is ample evidence that this should be abandoned in favor of multidetector CT for the C-spine. This is reflected in the ACR criteria in which conventional imaging of tile C-spine in trauma is rated as the least appropriate imaging method. However, this is not true in children and adolescents although a strict age criterion is not defined. It is also not true for injuries to the thoracic and lumbar spine in which conventional imaging still plays a large role as primary imaging modality followed by evaluation by CT in trauma situations. The role for MRI in acute situations is increasing especially with the increasing use of the TLICS system to classify injuries of the thoracic and lumbar spine in which the evaluation of the integrity of the posterior ligamentous structures is included. For the evaluation of chronic complaints, the roles of CT and MRI are basically reversed in which MRI will become the prime imaging modality of choice after conventional imaging after which CT can be reserved for a selected patient group. The merit of the different imaging modalities will be discussed together with a spectrum of acute and chronic injuries often encountered in the spine in athletes. PMID:24896742

de Jonge, Milko C; Kramer, Josef

2014-07-01

42

siRNA Genome Screening Approaches to Therapeutic Drug Repositioning  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Bridging high-throughput screening (HTS) with RNA interference (RNAi) has allowed for rapid discovery of the molecular basis of many diseases, and identification of potential pathways for developing safe and effective treatments. These features have identified new host gene targets for existing drugs paving the pathway for therapeutic drug repositioning. Using RNAi to discover and help validate new drug targets has also provided a means to filter and prioritize promising therapeutics. This re...

2013-01-01

43

Drug repositioning: a machine-learning approach through data integration  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Existing computational methods for drug repositioning either rely only on the gene expression response of cell lines after treatment, or on drug-to-disease relationships, merging several information levels. However, the noisy nature of the gene expression and the scarcity of genomic data for many diseases are important limitations to such approaches. Here we focused on a drug-centered approach by predicting the therapeutic class of FDA-approved compounds, not considering data concerning the d...

2013-01-01

44

Bony reconstruction by reposition of bony chips in suboccipital craniectomy  

Directory of Open Access Journals (Sweden)

Full Text Available In suboccipital craniectomy where the bone is not repositioned, there may be a significant cosmetic defect due to lack of skull bone in the suboccipital region. It may accompanied by sensory symptoms, including pain. To prevent any cosmetic defect and sensory symptoms we repositioned the bone chips at the craniectomy site in 42 suboccipital craniectomies before the closure of the scalp. At a mean follow-up of 22 months (range: 5-44 months, two patients complained of mild discomfort in the healed wound or of occasional local pain. One patient complained of mild itching at the site. In two patients, bone chips were accumulated at the lower part of the suboccipital craniectomy and failed to form a uniform bone cover at the operated site. In one patient, all bone chips were reabsorbed and there was no bone at the operated site. There was pseudomeningocele formation in one patient. In the rest of the cases there was satisfactory bone coverage at the operated site, both clinically and radiologically. The wound sites were aesthetically acceptable in 40 cases. Our study suggests that in the majority of cases where suboccipital craniotomy is not possible or not done, repositioning of the bone chips at the craniectomy site is associated with satisfactory aesthetic and functional outcome and formation of bone coverage at the operated site.

Chowdhury Forhad

2010-01-01

45

The value of drug repositioning in the current pharmaceutical market.  

Science.gov (United States)

Drug repositioning is the process of developing new indications for existing drugs or biologics. Increasing interest in drug repositioning has occurred due to sustained high failure rates and costs involved in attempts to bring new drugs to market. It has been estimated that it may cost more than USD 800 million to develop a new drug de novo. In addition, due to regulatory requirements regarding safety, efficacy and quality, the time required to develop a new drug de novo has been estimated to be 10 to 17 years. De novo drug discovery has failed to efficiently supply pharmaceutical company pipelines. A rational approach to drug repositioning may include a cross-disciplinary focus on the elucidation of the mechanisms of disease, allowing matching of disease pathways with appropriately targeted therapeutic agents. Repurposed drugs or biologics have the advantage of decreased development costs and decreased time to launch due to previously collected pharmacokinetic, toxicology and safety data. For these reasons, repurposing should be a primary strategy in drug discovery for every broadly focused, research-based pharmaceutical company. PMID:19330170

Tobinick, Edward L

2009-03-01

46

Cervical spine in psoriasis  

Digital Repository Infrastructure Vision for European Research (DRIVER)

X-rays of the cervical spines from patients with psoriasis and psoriatic arthritis were compared with similar films from a control population. Apophyseal narrowing, sclerosis, and calcification of anterior ligamants were found more commonly in patients than in controls

1995-01-01

47

Spine problems in adolescent  

Directory of Open Access Journals (Sweden)

Full Text Available Adolescent’s idiopathic scoliosis, Scheuermann kyphosis, spondylolysis and spondylolistesis are the most common spine problems of adolescence which needs orthopaedic treatment and follow-up. (Turk Arch Ped 2011; 46 Suppl: 65-7

Önder

2011-03-01

48

Pediatric cervical spine instability  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Cervical spine instability in children is rare but not exceptional and may be due to many factors. Although it mostly occurs at the upper cervical spine, all vertebrae from the occiput to T1 may be involved. It may be acute or chronic, occurring secondary to trauma or due to congenital anomaly, skeletal or metabolic dystrophy or rheumatoid arthritis. It can be isolated or associated with other musculoskeletal or visceral anomalies. A thorough knowledge of embryology, anatomy, physiology and p...

2008-01-01

49

Cervical spine trauma  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Cervical spine trauma is a common problem with a wide range of severity from minor ligamentous injury to frank osteo-ligamentous instability with spinal cord injury. The emergent evaluation of patients at risk relies on standardized clinical and radiographic protocols to identify injuries; elucidate associated pathology; classify injuries; and predict instability, treatment and outcomes. The unique anatomy of each region of the cervical spine demands a review of each segment individually. Thi...

Torretti, Joel A.; Sengupta, Dilip K.

2007-01-01

50

Laparoscopic lumbar spine surgery  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The use of transperitoneal endoscopic approaches to the distal segments of the lumbar spine has recently been described. This has been the catalyst for the development of other minimally invasive anterior ¶approaches to the spine. This review looks at the published results so ¶far, and highlights the principles, techniques and complications. The limitations of laparoscopic approaches have meant that surgeons are moving on to endoscopic extraperitoneal and mini-open approaches, but important...

O’dowd, J. K.

2000-01-01

51

Corporate Brand Repositioning with CSR as the Differentiating Factor: A Study on Consumer Perceptions  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Purpose – This research paper studies how the strategy of repositioning enables marketers to communicate CSR as their brand’s differentiating factor. It aims at understanding how consumer perceptions can be managed to generate brand value through corporate brand repositioning when CSR is the differentiating factor. The purpose of this paper is to answer the following research question: How can consumer perceptions be managed to generate brand value through corporate brand repositioning wh...

Vilppo, Tiina; Lindberg-repo, Kirsti

2011-01-01

52

Cervical spine trauma  

Directory of Open Access Journals (Sweden)

Full Text Available Cervical spine trauma is a common problem with a wide range of severity from minor ligamentous injury to frank osteo-ligamentous instability with spinal cord injury. The emergent evaluation of patients at risk relies on standardized clinical and radiographic protocols to identify injuries; elucidate associated pathology; classify injuries; and predict instability, treatment and outcomes. The unique anatomy of each region of the cervical spine demands a review of each segment individually. This article examines both upper cervical spine injuries, as well as subaxial spine trauma. The purpose of this article is to provide a review of the broad topic of cervical spine trauma with reference to the classic literature, as well as to summarize all recently available literature on each topic. Identification of References for Inclusion: A Pubmed and Ovid search was performed for each topic in the review to identify recently published articles relevant to the review. In addition prior reviews and classic references were evaluated individually for inclusion of classic papers, classifications and previously unidentified references.

Torretti Joel

2007-01-01

53

Ultrastructure of dendritic spines: correlation between synaptic and spine morphologies  

Directory of Open Access Journals (Sweden)

Full Text Available Dendritic spines are critical elements of cortical circuits, since they establish most excitatory synapses. Recent studies have reported correlations between morphological and functional parameters of spines. Specifically, the spine head volume is correlated with the area of the postsynaptic density (PSD, the number of postsynaptic receptors and the ready-releasable pool of transmitter, whereas the length of the spine neck is proportional to the degree of biochemical and electrical isolation of the spine from its parent dendrite. Therefore, the morphology of a spine could determine its synaptic strength and learning rules. To better understand the natural variability of neocortical spine morphologies, we used a combination of gold-toned Golgi impregnations and serial thin-section electron microscopy and performed three-dimensional reconstructions of spines from layer 2/3 pyramidal cells from mouse visual cortex. We characterized the structure and synaptic features of 144 completed reconstructed spines, and analyzed their morphologies according to their positions. For all morphological parameters analyzed, spines exhibited a continuum of variability, without clearly distinguishable subtypes of spines or clear dependence of their morphologies on their distance to the soma. On average, the spine head volume was correlated strongly with PSD area and weakly with neck diameter, but not with neck length. The large morphological diversity suggests an equally large variability of synaptic strength and learning rules.

JavierDeFelipe

2007-10-01

54

Repositioning of malpositioned or flipped central venous catheters  

International Nuclear Information System (INIS)

Primary misplaced or secondary flipped implanted catheters are located mostly in the right jugular vein. We demonstrate an effective method to replace fix implanted catheters such as Ports, Grochomg or Hickman catheters. Using a femoral venous approach, replacement into the superior vena cava can easily be done with a Sidewinder 1 catheter which is hooked over the misplaced central venous approach. In all our patients the method was successful. The repositioning technique described is simple, fast and has low costs. We can keep sterile conditions and do not need to solve the catheters' fixation. (orig.)

2002-03-01

55

Repositioning of malpositioned or flipped central venous catheters  

Energy Technology Data Exchange (ETDEWEB)

Primary misplaced or secondary flipped implanted catheters are located mostly in the right jugular vein. We demonstrate an effective method to replace fix implanted catheters such as Ports, Grochomg or Hickman catheters. Using a femoral venous approach, replacement into the superior vena cava can easily be done with a Sidewinder 1 catheter which is hooked over the misplaced central venous approach. In all our patients the method was successful. The repositioning technique described is simple, fast and has low costs. We can keep sterile conditions and do not need to solve the catheters' fixation. (orig.)

Thalhammer, A.; Jacobi, V.; Balzer, J.; Vogl, T.J. [Institute for Diagnostic and Interventional Radiology, Central Radiology Clinic, J.W. Goethe University, Frankfurt am Main (Germany)

2002-03-01

56

Repositioning of malpositioned or flipped central venous catheters.  

Science.gov (United States)

Primary misplaced or secondary flipped implanted catheters are located mostly in the right jugular vein. We demonstrate an effective method to replace fix implanted catheters such as Ports, Grochomg or Hickman catheters. Using a femoral venous approach, replacement into the superior vena cava can easily be done with a Sidewinder 1 catheter which is hooked over the misplaced central venous approach. In all our patients the method was successful. The repositioning technique described is simple, fast and has low costs. We can keep sterile conditions and do not need to solve the catheters' fixation. PMID:11870490

Thalhammer, A; Jacobi, V; Balzer, J; Vogl, T J

2002-03-01

57

Vertebroplasty for Spine Fracture Pain  

Science.gov (United States)

MENU Return to Web version Vertebroplasty for Spine Fracture Pain Vertebroplasty for Spine Fracture Pain More than 40 million people in the United States have osteoporosis (a decrease in the amount ...

58

[Surgical tactics in treatment of cervical spine injuries].  

Science.gov (United States)

Surgical tactics were analyzed in 1350 patients with cervical spine injuries treated during 1972-2009 years. In 80% of cases injuries were caused by car accidents. 855 patients were admitted in acute or early period of trauma. In other cases old injuries were observed. Vertebral neurological syndromes were revealed in most cases and were absent only in 80 patients. All patients were operated using anterior access. Authors consider that reposition of dislocated vertebras can be carried out in acute and early periods of trauma. Unsuccessful reposition, fractures or fracture-dislocations with spinal stenosis served as indications for transcorporal spinal decompression. This operation is considered to be a method of choice for late periods of trauma. Stabilization of spinal column was achieved using carbonic implant (950 patients), bone auto-transplant (400) combined with utilized auto-bone (960) or biocomposite material "KollapAn" (390 patients). Good results were achieved in 1150 patients, satisfactory - in 190, poor - in 10 patients. Long term results with catamnesis more than 25 years were traced in 120 patients. Results were not revalued. PMID:21350403

Protsenko, A I; Nikuradze, V K; Mekhtikhanov, D S

2011-01-01

59

Cervical spine in psoriasis  

Directory of Open Access Journals (Sweden)

Full Text Available X-rays of the cervical spines from patients with psoriasis and psoriatic arthritis were compared with similar films from a control population. Apophyseal narrowing, sclerosis, and calcification of anterior ligamants were found more commonly in patients than in controls

Banerjee Kalyan

1995-01-01

60

Recent Advances in Drug Repositioning for the Discovery of New Anticancer Drugs  

Science.gov (United States)

Drug repositioning (also referred to as drug repurposing), the process of finding new uses of existing drugs, has been gaining popularity in recent years. The availability of several established clinical drug libraries and rapid advances in disease biology, genomics and bioinformatics has accelerated the pace of both activity-based and in silico drug repositioning. Drug repositioning has attracted particular attention from the communities engaged in anticancer drug discovery due to the combination of great demand for new anticancer drugs and the availability of a wide variety of cell- and target-based screening assays. With the successful clinical introduction of a number of non-cancer drugs for cancer treatment, drug repositioning now became a powerful alternative strategy to discover and develop novel anticancer drug candidates from the existing drug space. In this review, recent successful examples of drug repositioning for anticancer drug discovery from non-cancer drugs will be discussed.

Shim, Joong Sup; Liu, Jun O.

2014-01-01

 
 
 
 
61

Lip repositioning surgery: A pioneering technique for perio-esthetics  

Science.gov (United States)

In our esthetic conscious society people are now demanding all types of treatments possible to have a pleasing and attractive personality. A dazzling and beautiful smile can work wonders for anyone's personality. Our smile mirrors our persona, our unique being. However, a beautiful smile comprises of a perfect balance of the white and pink. This imbalance of excessive gingival display (EGD) can be managed by a variety of treatment modalities, depending on accurate diagnosis. This case report demonstrates the successful management of EGD with a lip-repositioning procedure in a patient with incompetent short upper lip. This was accomplished by removing a partial thickness strip of mucosa from the maxillary buccal vestibule and suturing the lip mucosa to the mucogingival line. This resulted in a narrower vestibule and restricted muscle pull, thereby resulting in competent lips and reduced gingival display during smiling.

Grover, Harpreet Singh; Gupta, Anil; Luthra, Shailly

2014-01-01

62

siRNA Genome Screening Approaches to Therapeutic Drug Repositioning  

Directory of Open Access Journals (Sweden)

Full Text Available Bridging high-throughput screening (HTS with RNA interference (RNAi has allowed for rapid discovery of the molecular basis of many diseases, and identification of potential pathways for developing safe and effective treatments. These features have identified new host gene targets for existing drugs paving the pathway for therapeutic drug repositioning. Using RNAi to discover and help validate new drug targets has also provided a means to filter and prioritize promising therapeutics. This review summarizes these approaches across a spectrum of methods and targets in the host response to pathogens. Particular attention is given to the utility of drug repurposing utilizing the promiscuous nature of some drugs that affect multiple molecules or pathways, and how these biological pathways can be targeted to regulate disease outcome.

Ralph A. Tripp

2013-01-01

63

Infections of the spine  

International Nuclear Information System (INIS)

Diagnosis of infectious disease of the spine in an early stage ist difficult. Conventional X-ray examinations, often used as a basic screening study, will show the characteristic narrowing of the intervertebral disc space and the osteolytic and sclerotic changes in the adjointing vertebra only after two to eight weeks. Magnetic resonance imaging (MRI) has a sensitivity equivalent to bone scintigraphy and, due to its superior delineation of anatomic details, MRI has become the method of choice not only for the assessment of location, extent, and associated lesions in infectious bone disease, but also in the diagnosis of intradural infections including myelitis. MRI examination in the assessment of a successful therapy or osteomyelitis of the spine aims for the detection of regression of bone marrow edema, reappearance of fatty marrow, and less pronounced contrast enhancement. Computed tomography (CT) is mainly used for image-guided biopsy to obtain specimen for microbiologic culture or for the placement of a percutaneous drainage. (orig.)

1996-11-01

64

Cervical spine: degenerative conditions  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Degenerative cervical spine disorders will affect up to two-thirds of the population in their lifetime. While often benign and episodic in nature, cervical disorders may become debilitating resulting in severe pain and possibly neurologic sequelae. Non-operative treatment continues to play an important role in treating these patients, with medications, therapy and interventional pain injections playing increasing roles in treatment. Surgical treatment including anterior and posterior decompre...

Todd, Andrew G.

2011-01-01

65

Cervical Spine In Psoriasis  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Clinical study and X-ray of the cervical spine from patients with psoriasis and psoriatic arthritis were compared with similar films from a control population. Evidences suggest that neck is involved in psoriasis similar to those described for spondylitis. Apophyseal narrowing is 60% compared to 20% in control, apophyseal sclerosis is 40% compared to 15% in control, and an apophyseal calcification of anterior ligaments is 25% compared to 10% in control.

1995-01-01

66

Cervical Spine In Psoriasis  

Directory of Open Access Journals (Sweden)

Full Text Available Clinical study and X-ray of the cervical spine from patients with psoriasis and psoriatic arthritis were compared with similar films from a control population. Evidences suggest that neck is involved in psoriasis similar to those described for spondylitis. Apophyseal narrowing is 60% compared to 20% in control, apophyseal sclerosis is 40% compared to 15% in control, and an apophyseal calcification of anterior ligaments is 25% compared to 10% in control.

Banerjee Kalya

1995-01-01

67

Osteoblastoma of the spine  

Directory of Open Access Journals (Sweden)

Full Text Available A retrograde analysis of 64 spinal osteoblastomas treated by surgery during the period 1963 - 2005 has been made. Spinal osteoblastomas were presented in 36% of all skeletal localizations. There were 44 male and 20 female patients. The average age of patients at the time of surgery was14 years. Localizations of the osteoblastomas were cervical spine in 8 cases, dorsal spine in 16 cases, lumbar spine in 38 cases and sacrum in 2 cases. Osteoblastomas predominantly involved posterolateral vertebral elements, although in two cases a primary localization was in vertebral bodies. Neurological deficits were relatively moderate, but a paraplegia occurred in six patients. Scoliosis was present in 50% of cases, and their respective prognosis depended on the duration of the painful syndrome as well as on the age when the disease had set up. According to Enneking classification 30 patients were evaluated as stage 2 and 34 others as stage 3. Relapses were noticed in 8 (12.5% patients. Clearly delineated lesions were treated by an intralesional procedure, but aggressive ones were treated by a marginal surgery followed by additional radiotherapy (6 patients. The average follow - up period was 13 years.

Milinkovi? Z.B.

2010-01-01

68

Fractures of the Thoracic and Lumbar Spine  

Science.gov (United States)

... Orthopaedic Surgeons. Fractures of the Thoracic and Lumbar Spine A spinal fracture is a serious injury. The most common fractures of the spine occur in the thoracic (midback) and lumbar spine ( ...

69

Cervical Exercise: The Backbone of Spine Treatment  

Science.gov (United States)

North American Spine Society Public Education Series Cervical Exercise: The Backbone of Spine Treatment How important is it? What can be ... exercises. The Importance of Exercise for the Neck Spine experts agree that physical activity is important for ...

70

[Echinococcosis of the spine].  

Science.gov (United States)

21 patients with hydatid disease of the spine were operated on upon a 30-year period. The follow-up ranged up to 24 years. 12 cases underwent one or more reoperations, due to recurrences. 8 patients died between 1 and 21 years after the first operation. The surgical treatment usually allows only a transient remission and does not avoid recurrence or progression of the illness. Although the parasite cannot be wholly eradicated surgically, a prolonged and acceptable life with the disease can result from repeat surgical interference. PMID:3564762

Pau, A; Cossu, M; Viale, E S; Siccardi, D; Turtas, S; Viale, G L

1986-01-01

71

De novo spine surgery as a predictor of additional spine surgery at the same or distant spine regions  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction: Degenerative spine disorders are steadily increasing parallel to the aging of the population with considerable impact on cost and productivity. In this paper we study the prevalence and risk factors for multiple spine surgery and its impact on cost. Methods: Data on 1,153 spine surgery inpatients operated between October 2005 and September 2008 (index spine surgery in regard to the number of previous spine surgeries and location of surgeries (cervical or lumbar were retrospectively collected. Additionally, prospective follow-up over a period of 2-5 years was conducted. Results: Retrospectively, 365 (31.7% patients were recurrent spine surgery patients while 788 (68.3% were de novo spine surgery patients. Nearly half of those with previous spine surgery (51.5% were on different regions of the spine. There were no significant differences in length of stay or hospital charges except in lumbar decompression and fusion (LDF patients with multiple interventions on the same region of the spine. Significant differences (P<.05 in length of stay (5.4 days vs. 7.4 days and hospital charges ($55,477 vs. $74,878 between LDF patients with one previous spine versus those with ?3 previous spine surgeries on the same region were noted. Prospectively, the overall reoperation rate was 10.4%. The risk of additional spine surgery increased from 8.0% in patients with one previous spine surgery (index surgery to 25.6% in patients with ?4 previous spine surgeries on different regions of the spine (including index surgery. After excluding patients with previous spine surgeries on different regions of the spine, 17.2% of reoperated patients had additional spine surgery on a different spine region. The percentage of additional spine surgery on a distant spine region increased from 14.0% in patients with one spine surgery to 33.0% in patients with two spine surgeries on the same region. However, in patients with three or more spine surgeries on the same spine region there were no interventions on a distant spine region during the follow-up period. Conclusion: De novo spine surgery is associated with an increased incidence of additional spine surgery at the same or distant spine regions. Large prospective studies with extended follow-up periods and multifaceted cost-outcome analysis are needed to refine the appropriateness of spine surgery.

Tolaymat, Abdullah

2011-01-01

72

Numerical and experimental analysis of spine’s transpedicular stabilizer  

Directory of Open Access Journals (Sweden)

Full Text Available Purpose: The aim of the work was a numerical and experimental analysis of spine’s transpedicular stabilizer on lumbar part of spine. The result of the analysis was determination of displacements of the stabilizers’ elements.Design/methodology/approach: To define numerical characteristic of the lumbar spine – transpedicular spine stabilizer system, the finite element method was applied. Geometrical models of lumbar part of spine and transpedicular stabilizer were discretized by SOLID95 element. The boundary conditions imitating phenomena in real system with appropriate accuracy were established. The experimental analysis was carried out for spine’s transpedicular stabilizers which were implanted on lumbar part of pig spine. The analysis was realized by means of testing machine MTS Insight with the use of videoextensometer. Numerical and experimental analysis were carried out for stabilizer made of stainless steel Cr-Ni-Mo. System was loaded by uniaxial compression with forces from 50 N to 1600 N.Findings: The result of analysis was calculation of relative displacements of the transpedicular stabilizer in a function of the applied loading; F = 700 - 1600 N for numerical model and F = 50 - 1600 N for experimental model.Research limitations/implications: The results of numerical analysis for transpedicular stabilizer obtained by finite element method were used to determine a construction features of the stabilizer, and to select mechanical properties of metallic biomaterial. The calculation of displacements for stabilizer show that the proposed type of stabilizer enables correct stabilization of spine.Practical implications: Both results of numerical and experimental analysis showed correct selection of mechanical properties of metallic biomaterial which were used to made the proposed type of transpedicular stabilizer.Originality/value: Advantageous results of analysis showed that the type of stabilizer may be used in clinical practice.

M. Kiel

2010-07-01

73

Acute hypoxaemia due to intraoperative lung collapse after repositioning the patient  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Desaturation after induction of anaesthesia and repositioning due to mucus plug causing atelectasis (lung collapse) is a rare event. We present a case of intraoperative right lung collapse due to mucus plug in a patient undergoing left laparoscopic nephrectomy. Hypoxaemia occurred after the induction of anaesthesia and repositioning. X-ray chest revealed right lung collapse and surgery was subsequently postponed. Lung re-expanded after postural drainage and suction. Postoperatively patient wa...

Butala, Bina P.; Shah, Veena R.; Bhosale, Guruprasad P.

2011-01-01

74

Frequent manual repositioning and incidence of pressure ulcers among bedbound elderly hip fracture patients  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Frequent manual repositioning is an established part of pressure ulcer (PU) prevention, but there is little evidence for its effectiveness. This study examined the association between repositioning and PU incidence among bedbound elderly hip fracture patients, using data from a 2004–2007 cohort study in nine Maryland and Pennsylvania hospitals. Eligible patients (n=269) were age?65 years, underwent hip fracture surgery, and were bedbound at index study visits (during the first five days o...

Rich, Shayna E.; Margolis, David; Shardell, Michelle; Hawkes, William G.; Miller, Ram R.; Amr, Sania; Baumgarten, Mona

2011-01-01

75

Temporomandibular joint disc repositioning using bone anchors: an immediate post surgical evaluation by Magnetic Resonance Imaging  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Abstract Background Open joint procedures using bone anchors have shown clinical and radiograph good success, but post surgical disc position has not been documented with MRI imaging. We have designed a modified technique of using two bone anchors and 2 sutures to reposition the articular discs. This MRI study evaluates the post surgical success of this technique to reposition and stabilize the TMJ articular discs. Methods Consecutive 81 patients with unilateral...

Zhang ShanYong; Liu XiuMing; Yang XiuJuan; Yang Chi; Chen MinJie; Haddad Majd S; Chen ZhuoZhi

2010-01-01

76

Cervical and thoracic spine  

International Nuclear Information System (INIS)

Many facilities with confidence and expertise in lumbar CT work have met with considerable disappointment when attempting to extend their diagnostic capabilities to the cervical spine. The authors' experience is no exception, and in retrospect, there are two main reasons: differences in the gross sizes of anatomic structures and in the appropriateness of scanning and filming protocols. The second major reason for early disappointment in cervical work was the incorrect assumption that a single scanning and filming protocol would be as appropriate for cervical examinations as it was for lumbar examinations. Optimal cervical CT diagnosis requires more flexibility in terms of image manipulation and display options. Disorders of the cervical spine fall into four broad groups: (1) localized lesions of the craniocervical junction;(2) nonarthritic lesions of bone at any cervical level;(3) diseases of the spinal cord, and (4) degenerative diseases of the disc and the vertebral joint. It is very important for the scanning protocol to be tailored to the primary diagnostic category

1985-01-01

77

Baastrup's disease: The kissing spine.  

Science.gov (United States)

A 67-year-old male presented with a gradually progressive low back pain of 2 years duration. The patient was leading a retired life and there was no history of chronic fever or significant trauma. There was no radiation of pain or any features suggestive of claudication. There was no history of any comorbidity. The pain was aggravated with extension of the spine and relieved with flexion. There was no swelling or neurological deficit, but muscle spasm was present. Radiographs of the spine revealed degenerative changes in the lumbosacral spine, along with articulation of spinous processes at in lumbar spine at all levels level suggestive of Baastrup's disease, commonly known as "kissing spine". Routine blood investigations were within normal limits. The patient was managed conservatively. He was given a week's course of analgesics and muscle relaxants and then started on spinal flexion exercises, with significant improvement being noted at 6 months follow up. PMID:24579072

Singla, Amit; Shankar, Vivek; Mittal, Samarth; Agarwal, Abhinav; Garg, Bhavuk

2014-02-16

78

Stochastic description of single nucleosome repositioning by ACF remodelers  

Science.gov (United States)

Chromatin remodeling plays a crucial role in the activation or repression of transcription of eukaryotic genes. The chromatin remodeler ACF acts as a dimeric, processive motor to evenly space nucleosomes, favoring repression of gene transcription. Single-molecule experiments have established that ACF moves the nucleosome more efficiently towards the longer flanking DNA than towards the shorter flanking DNA, thereby centering an initially ill-positioned nucleosome on DNA substrates. In this paper we present a one-motor model with nucleosomal repositioning rates dependent on the DNA flanking length. The corresponding master equation is solved analytically with experimentally relevant parameter values. The velocity profile and the effective diffusion constant for nucleosome sliding, computed from the probability distributions, are in accordance with available experimental data. In order to address the observed kinetic pauses in experimental Förster Resonance Energy Transfer profiles, we extend the master equation to account for transitions between explicit motor states, i.e., adenosine triphosphate (ATP) loading and ATP hydrolysis in both ACF motors. The results of this extended two-motor model are compared to the previous effective one-motor model and allow insights into the role of the synchronization of the two motors acting on the nucleosome.

Vandecan, Yves; Blossey, Ralf

2012-06-01

79

Preliminary evaluation of robotic needle distal tip repositioning  

Science.gov (United States)

Advances in medical imaging now provide detailed images of solid tumors inside the body and miniaturized energy delivery systems enable tumor destruction through local heating powered by a thin electrode. We have developed a robot for accurately repositioning the distal tip of a medical instrument such an ablation probe to adjacent points within tissue. The position accuracy in ballistics gelatin was evaluated in a 2D experimental setup with a digital SLR camera that was fixed to a rig that also contained the gelatin. The robot was mounted to the rig in such a way that the stylet was deployed in a plane parallel the camera's lens. A grid paper attached to the back of the box containing the gelatin provided a stationary reference point for each of the pictures taken and also served as a coordinate system for making measurements. The measurement repeatability error was found by taking a stylet tip position measurement five times for two different pictures and found to be 0.26 mm. For a stylet with a radius of curvature of 31.5 mm and a diameter of 0.838 mm, the targeting accuracy was found to be 2.5 +/- 1.4 mm at points that were approximately 38 mm lateral from the cannula axis.

Walsh, Conor J.; Slocum, Alexander H.; Gupta, Rajiv

2011-02-01

80

Initial experience with a telerobotic system to remotely navigate and automatically reposition standard steerable EP catheters.  

Science.gov (United States)

The use of robotic systems in cardiac interventional procedures is growing. The insertion and maneuvering in the human body of electrophysiology (EP) catheters is currently carried out manually under fluoroscopic guidance, resulting in operator fatigue and prolonged x-ray exposure. We report our initial animal experience with a novel telerobotic system (TS) to remotely navigate and automatically reposition standard steerable EP catheters within the heart. We developed a TS able to guide, as a "robotic hand," EP catheters without the need of dedicated catheters and cumbersome devices. During tests on three sheep, catheter navigation and repositioning to 12 predefined endocardial targets were previously performed by conventional manual procedure and then using the TS implemented with an automatic catheter repositioning function. All the predefined targets were reached under fluoroscopy visualization, and procedural times were measured during catheter navigation and repositioning. The use of the TS slightly reduced the time necessary for catheter navigation compared with the conventional manual procedure (13.0 +/- 5.6 vs 16.1 +/- 6.4 seconds, p < 0.001) and significantly decreased the time for a precise catheter repositioning (9.2 +/- 2.5 vs 17.8 +/- 7.1 sec, p < 0.001). The TS proved to be a promising tool for remote navigation of standard EP catheters reducing the time necessary for catheter repositioning. PMID:17885323

Cercenelli, Laura; Marcelli, Emanuela; Plicchi, Gianni

2007-01-01

 
 
 
 
81

Fractures of the cervical spine  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in english OBJECTIVES: The aim of this study was to review the literature on cervical spine fractures. METHODS: The literature on the diagnosis, classification, and treatment of lower and upper cervical fractures and dislocations was reviewed. RESULTS: Fractures of the cervical spine may be present in pol [...] ytraumatized patients and should be suspected in patients complaining of neck pain. These fractures are more common in men approximately 30 years of age and are most often caused by automobile accidents. The cervical spine is divided into the upper cervical spine (occiput-C2) and the lower cervical spine (C3-C7), according to anatomical differences. Fractures in the upper cervical spine include fractures of the occipital condyle and the atlas, atlanto-axial dislocations, fractures of the odontoid process, and hangman's fractures in the C2 segment. These fractures are characterized based on specific classifications. In the lower cervical spine, fractures follow the same pattern as in other segments of the spine; currently, the most widely used classification is the SLIC (Subaxial Injury Classification), which predicts the prognosis of an injury based on morphology, the integrity of the disc-ligamentous complex, and the patient's neurological status. It is important to correctly classify the fracture to ensure appropriate treatment. Nerve or spinal cord injuries, pseudarthrosis or malunion, and postoperative infection are the main complications of cervical spine fractures. CONCLUSIONS: Fractures of the cervical spine are potentially serious and devastating if not properly treated. Achieving the correct diagnosis and classification of a lesion is the first step toward identifying the most appropriate treatment, which can be either surgical or conservative.

Raphael Martus, Marcon; Alexandre Fogaca, Cristante; William Jacobsen, Teixeira; Douglas Kenji, Narasaki; Reginaldo Perilo, Oliveira; Tarcisio Eloy Pessoa de, Barros.

82

Massive Pneumocephalus And Meiningitis Following Spine Instrumentation  

Directory of Open Access Journals (Sweden)

Full Text Available Pneumocephalus with meningitis usually occurs as a complication of head injury or surgery. It is uncommon after procedures or traumatic injuries to spine. We report an adolescent presenting with features of Pott?s spine who developed pneumocephalus and meningitis following spine instrumentation (stabilization of thoracic spine. Early recognition and prompt treatment with parenteral antibiotics resulted in a favorable outcome.

Kumar S

2005-01-01

83

De novo spine surgery as a predictor of additional spine surgery at the same or distant spine regions  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Introduction: Degenerative spine disorders are steadily increasing parallel to the aging of the population with considerable impact on cost and productivity. In this paper we study the prevalence and risk factors for multiple spine surgery and its impact on cost.Methods: Data on 1,153 spine surgery inpatients operated between October 2005 and September 2008 (index spine surgery) in regard to the number of previous spine surgeries and location of surgeries (cervical or lumbar) were retrospec...

Walid, Ms; Robinson Iii, Js; Abbara, M.; Tolaymat, A.; Robinson Jr, Js

2011-01-01

84

CASTOR: Cathode/Anode Satellite Thruster for Orbital Repositioning  

Science.gov (United States)

The purpose of CASTOR (Cathode/Anode Satellite Thruster for Orbital Repositioning) satellite is to demonstrate in Low Earth Orbit (LEO) a nanosatellite that uses a Divergent Cusped Field Thruster (DCFT) to perform orbital maneuvers representative of an orbital transfer vehicle. Powered by semi-deployable solar arrays generating 165W of power, CASTOR will achieve nearly 1 km/s of velocity increment over one year. As a technology demonstration mission, success of CASTOR in LEO will pave the way for a low cost, high delta-V orbital transfer capability for small military and civilian payloads in support of Air Force and NASA missions. The educational objective is to engage graduate and undergraduate students in critical roles in the design, development, test, carrier integration and on-orbit operations of CASTOR as a supplement to their curricular activities. This program is laying the foundation for a long-term satellite construction program at MIT. The satellite is being designed as a part of AFRL's University Nanosatellite Program, which provides the funding and a framework in which student satellite teams compete for a launch to orbit. To this end, the satellite must fit within an envelope of 50cmx50cmx60cm, have a mass of less than 50kg, and meet stringent structural and other requirements. In this framework, the CASTOR team successfully completed PDR in August 2009 and CDR in April 2010 and will compete at FCR (Flight Competition Review) in January 2011. The complexity of the project requires implementation of many systems engineering techniques which allow for development of CASTOR from conception through FCR and encompass the full design, fabrication, and testing process.

Mruphy, Gloria A.

2010-01-01

85

Magnetic Resonance Imaging (MRI) - Spine  

Science.gov (United States)

Magnetic Resonance Imaging (MRI) - Spine • Overview Magnetic resonance imaging (MRI) is a noninvasive medical test that helps physicians diagnose and treat medical conditions. MRI uses a powerful magnetic field, radio frequency ...

86

Typhoid spine - A case report  

Directory of Open Access Journals (Sweden)

Full Text Available A case of Salmonella typhi isolated from L4-L5 spine is reported here. The causative organism was not suspected preoperatively. The patient responded favourably to surgical drainage and appropriate antibiotic therapy.

Rajesh P

2004-01-01

87

Biomechanics of the aging spine  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The human spine is composed of highly specific tissues and structures, which together provide the extensive range of motion and considerable load carrying capacity required for the physical activities of daily life. Alterations to the form and composition of the individual structures of the spine with increasing age can increase the risk of injury and can have a profound influence on the quality of life. Cancellous bone forms the structural framework of the vertebral body. Individual trabecul...

Ferguson, Stephen J.; Steffen, Thomas

2003-01-01

88

Radiation Exposure During Head Repositioning With the Automatic Positioning System for Gamma Knife Radiosurgery  

International Nuclear Information System (INIS)

Purpose: To measure radiation exposure to a patient during head repositioning with the automatic positioning system (APS) for Gamma Knife radiosurgery. Methods and Materials: A 16-cm diameter spherical solid phantom, provided by the manufacturer, was mounted to the APS unit using a custom-made holder. A small-volume ionization chamber (0.07-cm3 volume) was placed at the center of the phantom. We recorded the temporal variation of ionization current during the entire treatment. Measurements were made for 3 test cases and 7 clinical cases. Results: The average transit time between successive shots, during which the APS unit was moving the phantom for repositioning the shot coordinates, was 20.5 s for 9 cases. The average dose rate, which was measured at the center of the phantom and at a point outside the shot location, was 0.36 ± 0.09 cGy/min when the beam output was approximately 3.03 Gy/min for the 18-mm collimator helmet. Hence, the additional intracranial radiation dose during the APS-driven head repositioning between two successive shots (or APS transit dose) was 0.12 ± 0.050 cGy. The APS transit dose was independent of the helmet size and the position of shots within the phantom relative to the measurement point. Conclusion: The head repositioning with the APS system adds a small but not negligible dose to the dose expected for the manual repositioning method

2007-07-15

89

Radiology illustrated. Spine  

Energy Technology Data Exchange (ETDEWEB)

Offers a practical approach to image interpretation for spinal disorders. Includes numerous high-quality radiographic images and schematic illustrations. Will serve as a self-learning book covering daily routine cases from the basic to the advanced. Radiology Illustrated: Spine is an up-to-date, superbly illustrated reference in the style of a teaching file that has been designed specifically to be of value in clinical practice. Common, critical, and rare but distinctive spinal disorders are described succinctly with the aid of images highlighting important features and informative schematic illustrations. The first part of the book, on common spinal disorders, is for radiology residents and other clinicians who are embarking on the interpretation of spinal images. A range of key disorders are then presented, including infectious spondylitis, cervical trauma, spinal cord disorders, spinal tumors, congenital disorders, uncommon degenerative disorders, inflammatory arthritides, and vascular malformations. The third part is devoted to rare but clinically significant spinal disorders with characteristic imaging features, and the book closes by presenting practical tips that will assist in the interpretation of confusing cases.

Kang, Heung Sik; Lee, Joon Woo [Seoul National Univ. Bundang Hospital, Seongnam, Kyonggi-do (Korea, Republic of). Dept. of Radiology; Kwon, Jong Won [Samsung Medical Center, Seoul (Korea, Republic of). Dept. of Radiology

2014-04-01

90

Radiology illustrated. Spine  

International Nuclear Information System (INIS)

Offers a practical approach to image interpretation for spinal disorders. Includes numerous high-quality radiographic images and schematic illustrations. Will serve as a self-learning book covering daily routine cases from the basic to the advanced. Radiology Illustrated: Spine is an up-to-date, superbly illustrated reference in the style of a teaching file that has been designed specifically to be of value in clinical practice. Common, critical, and rare but distinctive spinal disorders are described succinctly with the aid of images highlighting important features and informative schematic illustrations. The first part of the book, on common spinal disorders, is for radiology residents and other clinicians who are embarking on the interpretation of spinal images. A range of key disorders are then presented, including infectious spondylitis, cervical trauma, spinal cord disorders, spinal tumors, congenital disorders, uncommon degenerative disorders, inflammatory arthritides, and vascular malformations. The third part is devoted to rare but clinically significant spinal disorders with characteristic imaging features, and the book closes by presenting practical tips that will assist in the interpretation of confusing cases.

2014-01-01

91

Long-Term Efficacy of Repositioning Maneuvers in Benign Paroxysmal Positional Vertigo  

Directory of Open Access Journals (Sweden)

Full Text Available To determine the characteristics of 12 patients with a diagnosis of benign paroxysmal positional vertigo (BPPV treated by the repositioning maneuver during a 24-month follow-up period after the initial discharge a longitudinal clinical study was performed in which a questionnaire for the assessment of discomfort caused by dizziness was applied at the first visit, at the last visit after treatment and 2 years after the initial discharge. Repositioning treatment was again offered to patients who suffered relapses. In 10 cases (83.34% there was no recurrence of symptoms and 2 patients (16.66% presented symptoms exactly 2 years after the original discharge showing that treatment of BPPV by repositioning manuevers is effective in the long term, but new studies in larger populations are needed to determine the pattern of the rates of recurrence of BPPV.

Julio Cesar Moriguti

2011-05-01

92

Influence of surgical repositioning of mature permanent dog teeth following experimental intrusion: a histologic assessment.  

Science.gov (United States)

The aim of this study was to evaluate, through histologic examination, the effect of surgical repositioning of intruded dog teeth upon the pulpal and surrounding tissues. Thirty teeth in 10 adult dogs, aged 2-3 years, were used. Fifteen teeth were intruded, surgically repositioned and fixed using orthodontics wire, composite resin, and enamel acid conditioning. All these teeth served as the experimental group. The remaining intruded teeth were not treated (control group). The animals were sacrificed to allow observations at 7, 15, and 30 post-operative days. The maxillary and mandibular arches were removed and processed for histologic exam. Based on the methodology and observed results, we concluded that: pulpal necrosis, external root resorption and ankylosis were common sequelae to severe traumatic intrusion; a careful immediate surgical repositioning of severed intruded permanent tooth with complete root formation has many advantages with few disadvantages. PMID:12656863

Cunha, R F; Pavarini, A; Percinoto, C; Lima, J E O

2002-12-01

93

Fractionated brain stereotactic radiotherapy: assessment of repositioning precision using a thermoforming mask  

International Nuclear Information System (INIS)

The authors report a study which aimed at assessing the patient repositioning precision obtained with a support system used during a brain fractionated stereotactic radiotherapy and comprising a thermoforming mask (Elektra head mask). The repositioning is assessed by means of scano-graphies and superimposition with the stereotactic frame. A three-dimensional vector has been computed for each patient. The average displacement corresponds to that published in literature. The high quality of the support system allows a non invasive brain stereotactic radiotherapy to be performed which is also comfortable for the patient. Short communication

2011-10-01

94

Acute hypoxaemia due to intraoperative lung collapse after repositioning the patient.  

Science.gov (United States)

Desaturation after induction of anaesthesia and repositioning due to mucus plug causing atelectasis (lung collapse) is a rare event. We present a case of intraoperative right lung collapse due to mucus plug in a patient undergoing left laparoscopic nephrectomy. Hypoxaemia occurred after the induction of anaesthesia and repositioning. X-ray chest revealed right lung collapse and surgery was subsequently postponed. Lung re-expanded after postural drainage and suction. Postoperatively patient was diagnosed to have retrocardiac bronchiectasis. After preoperative preparation with postural drainage, chest physiotherapy, and antibiotics, the patient underwent surgery uneventfully. PMID:22013260

Butala, Bina P; Shah, Veena R; Bhosale, Guruprasad P

2011-07-01

95

Repositioning Secondary School Administration for Quality Assurance in Ekiti State, Nigeria  

Directory of Open Access Journals (Sweden)

Full Text Available This paper discusses the challenges and prospects of repositioning secondary school administration for quality assurance in Ekiti State, Nigeria. In recent time, there had been a radical transformation of the education sector in Ekiti State part of which included the restructuring of the secondary school system. The senior and junior secondary schools were merged together to become a single school under the administration of a school principal. This paper examines the strategies used in repositioning secondary school administration for quality assurance by the state government. It highlights the challenges of repositioning the school administration based on the public outcry and the reactions of the school principals towards this new development. It x- rays the prospects of repositioning secondary school administration for quality assurance in Ekiti State to include high competency of secondary school administrators, removal of dichotomy between senior and junior secondary schools, unity and team work spirit among teachers, centralization of school policies, improved school infrastructures and facilities, and effective supervision of school personnel. The paper recommended among others that the Teaching Service Commission in Ekiti State should always consider performance, competency and years of experience in the appointment of secondary school principals.

Babatope Kolade Oyewole

2013-07-01

96

Optimization of the repositioning of critical assemblies in a nuclear reactor  

International Nuclear Information System (INIS)

It is proposed to optimize the repositioning of fuel assemblies in the core of a reactor. The reactor core is characterized by the smallest eigenvalue associated to the eigenvector of a partial differential equations system. In the first step the discrete variables are replaced by continuous ones and in the second step, the best approach of the optimal configuration obtained is secked

1980-12-00

97

Stabilization of premaxilla repositioned during secondary bone grafting in complete bilateral cleft lip and palate patients.  

Science.gov (United States)

Secondary bone grafting simultaneous to premaxillary repositioning is a well-recognized surgical procedure for the management of bilateral cleft lip and palate patients. Proper stabilization of the repositioned premaxilla is considered as a key factor for the success of secondary bone grafting because the mobility of the premaxillary segment jeopardizes graft integration. This case series reports a reliable method of premaxillary stabilization that incorporated the intrasurgical application of resin bone cement to cover and reinforce the arch bars or orthodontic brackets applied on the maxillary teeth. Occlusal loads were reduced by application of posterior bite blocks on the mandibular teeth. The stabilization method was performed on 7 patients (5 women and 2 men) with a mean age of 12.4 years. During postsurgery follow-ups, the repositioned premaxillary segments did not show mobility in any of the patients. The palatal fistulae were completely closed. Panoramic radiographies taken 2 months after surgery demonstrated acceptable graft integration. The patients have now been followed up to 5 years. No evidence of relapse has been observed. This technique seemed to be undemanding, included minimal laboratory procedure, and maintained the labial mucosa overlying the repositioned segment intact. PMID:24926720

Behnia, Hossein; Mesgarzadeh, Abolhasan; Tehranchi, Azita; Morad, Golnaz; Samieerad, Sahand; Younessian, Farnaz

2014-07-01

98

Unraveling the Threads of White Teachers' Conceptions of Caring: Repositioning White Privilege  

Science.gov (United States)

This study explored two White inservice teachers' understandings of Whiteness in relation to privilege and caring. A yearlong professional development set of courses used a multimodal construction of three significant course experiences designed to reposition Whiteness and illuminate White teachers' predisposition to care for their students in…

Pennington, Julie L.; Brock, Cynthia H.; Ndura, Elavie

2012-01-01

99

Pre and post garter spring repositioning ultrasonic inspection of pressure tubes  

International Nuclear Information System (INIS)

This paper present a description of the ultrasonic cracked hydride blister detections system used for pre and post inspection of pressure tubes during garter spring repositioning in CNE (Embalse Nuclear Power Station). Ultrasonic system setup configuration, transducers characteristics, blister detection head, calibration of parameters, operating procedure, records of ultrasonic inspections and evaluation. (author)

1997-10-27

100

Delayed Herniation of Coil Loop and Spontaneous Reposition in a Superior Cerebellar Artery Aneurysm  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Herniation of coil loops into the parent artery is one of the complications of endovascular embolization with detachable coils. In this clinical setting, we cannot predict the consequence of the herniated coil loop. We report an unusual case of a superior cerebellar artery (SCA) aneurysm with delayed coil herniation into the basilar artery and spontaneous reposition into the SCA.

Sim, Ki Bum; Park, Ji Kang; Kwon, O-ki; Park, Jung Cheol

2011-01-01

 
 
 
 
101

Development of a criterion for repositioning a relocatable stereotactic frame using depth helmet measurements  

International Nuclear Information System (INIS)

Based on 95% confidence intervals in the normal distribution, a criterion was developed for a relocatable stereotactic frame depth helmet measurement. The method for obtaining such a criterion is described. The criterion states that, if more than two points deviate more than 1.5 mm the frame should be repositioned

2001-10-01

102

49 CFR 572.187 - Lumbar spine.  

Science.gov (United States)

... 7 2010-10-01 2010-10-01 false Lumbar spine. 572.187 Section 572.187 Transportation...Dummy, 50th Percentile Adult Male § 572.187 Lumbar spine. (a) The lumbar spine assembly consists of parts shown in...

2010-10-01

103

49 CFR 572.187 - Lumbar spine.  

Science.gov (United States)

... 2010-10-01 2010-10-01 false Lumbar spine. 572.187 Section 572.187 Transportation...50th Percentile Adult Male § 572.187 Lumbar spine. (a) The lumbar spine assembly consists of parts shown in drawing...

2010-10-01

104

Magnetic resonance of the spine  

Energy Technology Data Exchange (ETDEWEB)

This book contains 12 chapters. Three chapters discuss principles of cerebrospinal fluid flow, spinal imaging techniques, and the physical basis and anatomic correlates of signal intensity in the spine. There are chapters on normal anatomy, congenital anomalies, trauma, tumors, infection, demyelinating disease, degenerative disease, vascular conditions, and syringomyelia.

Enzmann, D.R.; De La Paz, R.L.; Rubin, J.R.

1990-01-01

105

Concept of gunshot wound spine.  

Science.gov (United States)

Gunshot wound (GSW) to the spine which was earlier common in the military population is now being increasingly noted in civilians due to easy availability of firearms of low velocity either licensed or illegal combined with an increased rate of violence in the society. Contributing to 13% to 17% of all spinal injuries, the management of complex injury to the spine produced by a GSW remains controversial. Surgery for spinal cord injuries resulting from low velocity GSWs is reserved for patients with progressive neurologic deterioration, persistent cerebrospinal fluid fistulae, and sometimes for incomplete spinal cord injuries. Surgery may also be indicated to relieve active neural compression from a bullet, bone, intervertebral disk, or a hematoma within the spinal canal. Spinal instability rarely results from a civilian GSW. Cauda equina injuries from low velocity GSWs have a better overall outcome after surgery. In general, the decision to perform surgery should be made on consideration of multiple patient factors that can vary over a period of time. Although there have been plenty of individual case reports regarding GSW to the spine, a thorough review of unique mechanical and biological factors that affect the final outcome has been lacking. We review the key concepts of pathogenesis and management of GSW to the spine and propose an algorithm to guide decision making in such cases. PMID:24353856

Jaiswal, Manish; Mittal, Radhey Shyam

2013-12-01

106

Radiology of the cervical spine  

International Nuclear Information System (INIS)

The author describes some particularities seen in the abnormal or pathological image of the cervical spine: The osteolysis of the cortical bone in the spinous processes, the 'Y' shaped course of the corporeal veins, the notch in interspinous bursitis, and the main forms of constitutional stenosis of the cervical canal. (orig.)

1989-01-01

107

Radiology of the cervical spine  

Energy Technology Data Exchange (ETDEWEB)

The author describes some particularities seen in the abnormal or pathological image of the cervical spine: The osteolysis of the cortical bone in the spinous processes, the 'Y' shaped course of the corporeal veins, the notch in interspinous bursitis, and the main forms of constitutional stenosis of the cervical canal.

Wackenheim, A.

1989-04-01

108

Imaging of cervical spine injuries of childhood  

Energy Technology Data Exchange (ETDEWEB)

Cervical spine injuries of children, though rare, have a high morbidity and mortality. The pediatric cervical spine is anatomically and biomechanically different from that of adults. Hence, the type, level and outcome of cervical spine injuries in children are different from those seen in adults. Normal developmental variants seen in children can make evaluation of the pediatric cervical spine challenging. This article reviews the epidemiology of pediatric cervical spine trauma, normal variants seen in children and specific injuries that are more common in the pediatric population. We also propose an evidence-based imaging protocol to avoid unnecessary imaging studies and minimize radiation exposure in children. (orig.)

Khanna, Geetika; El-Khoury, Georges Y. [University of Iowa Hospitals and Clinics, Department of Radiology, 3951 JPP, Iowa, IA (United States)

2007-06-15

109

Cervical spine in Treacher Collins syndrome.  

Science.gov (United States)

Treacher Collins syndrome is a congenital syndrome with characteristic craniofacial malformations, which are well described in the literature. However, the presence of cervical spine dysmorphology in this syndrome has been minimally described. This study reviews cervical spine radiographs of 40 patients with Treacher Collins syndrome. In this sample, 7 of 40 patients displayed cervical spine anomalies, with 3 of these patients displaying multiple cervical spine anomalies. The patterns of spinal anomalies were variable, suggesting that the underlying genetic mutation has variable expressivity in cervical spine development as it does elsewhere in the craniofacial skeleton. PMID:22627438

Pun, Amy Hoi-Ying; Clark, Bruce Eric; David, David John; Anderson, Peter John

2012-05-01

110

Targeting the new generation woman: voice-over as a tool in gender repositioning traditionally male dominant product  

Digital Repository Infrastructure Vision for European Research (DRIVER)

This exploratory research study examines the power of the voice-over as a tool in gender re-positioning of a traditionally male dominant product and the response of the female market to such re-positioning. The increasing consumption by females of masculine products has led marketers to question how they can target such products at the female market, without losing the existing male customers. A potentially appropriate method of doing so is through subtle gender re-positioning by altering the...

Staunton, Ciara

1995-01-01

111

Repositioning the patient: the implications of being 'at risk'.  

Science.gov (United States)

In the modern era of biomedical practice, genetic knowledge has redefined the idea of 'the patient' to include those who are 'at risk' of disease alongside those who are already sick. For such individuals, it is risk itself that constitutes the raison d'être of medical intervention. Using data from interviews with 58 users of a UK cancer genetics service together with data derived from clinical consultations, we consider the way such patients or clients make sense of a cancer genetic risk estimate and how they integrate genetic risk information into their lifeworld. In particular, we note that patient-clients who are 'at risk' tend to see themselves in a liminal position betwixt the healthy and the sick, and that such individuals consequently seek recourse to systems of medical surveillance that can continuously monitor their state of health. Our analysis also revealed the fact that many of those deemed by professionals to be at low risk of inheriting cancer-related mutations subsequently strove to be re-categorised as being at moderate or high risk of an adverse outcome. A number of explanations concerning lay health beliefs, lay 'representations' of health and the nature of the patient-client's lifeworld are examined and assessed in order to account for this apparent paradox. PMID:15686817

Scott, S; Prior, L; Wood, F; Gray, J

2005-04-01

112

Intraoperative neuromonitoring: lessons learned from 32 case events in 2095 spine cases  

Science.gov (United States)

Study type:?Restrospective chart review Introduction:?Intraoperative neuromonitoring is becoming the standard of care for many more spinal surgeries, especially with deformity correction and instrumentation. We reviewed our institution's neuromonitored spine cases over the past 4 years to see the immediate intraoperative and postoperative clinical findings when an intraoperative neuromonitoring event was noted. Objective:?The main question addressed in this review is how multimodality intraoperative neuromonitoring has affected our ability to avoid potential neurological injury during spine surgery. Methods:?We retrospectively reviewed 2,095 neuromonitored spine cases at one institution performed over a period of 4 years. Data from the single neuromonitoring provider (Impulse Monitoring, Inc.) at our institution was collected and any cases with possible intraoperative events were isolated. The intraoperative and immediate postoperative clinical documentation of these 32 cases were reviewed (Table 1). Table 1 Summary of each case event with the type of procedure, intraoperative findings, intraoperative intervention, and postoperative findings Case Procedure Intraoperative findings Intraoperative intervention Postoperative findings 1 Posterior cervical decopression Loss of MEP Increased blood preasure No deficit 2 Cervicothoracic spinal cord lesion biopsy Loss of MEP in lower extremities None Bilateral lower extremity paresis 3 Thoracic spinal cord tumor debulking Loss of MEP in right lower extremity None Right lower extremity paralysis 4 Posterior lumbosacral decompression/fusion TLIF Low S1 screw threshold Screw checked, repositioned No deficit 5 Posterior lumbar decompression/fusion None None Foot drop, medial L4 screw breach 6 Cervicomedullary spinal cord tumor resection Loss of left upper extremity SSEP None Left upper extremity sensory deficit 7 Anterior thoracic discectomies/partial corpectomies Left upper extremity decreased SSEP Carm pressing on arm, removed No deficit 8 Posterior lumbosacral decompression/fusion TLIF Right upper extremity decreased SSEP Arm repositioned No deficit 9 C7–T1 anterior decompression/fusion Right lower extremity decreased MEP Increased blood preasure No deficit 10 T11–L5 anterior discectomy/fusion Right lower extremity decreased SSEP, MEP Increased blood preasure No deficit 11 Posterior thoracolumbar decompression/fusion TLIF Left lower extremity decreased SSEP Increased blood preasure No deficit 12 Posterior thoracolumbar decompression/fusion costotransversectomy T11, T12, L1 partial vertebrectomies Right lower extremity decreased SSEP, MEP Stopped procedure, stage 1 of 2 No deficit 13 Posterior thoracolumbar decompression/fusion TLIF Variable SSEP, MEP Labile blood preasure No deficit 14 Posterior occipitocervical decompression/fusion Right upper extremity decreased SSEP Positioning effect, arm tucked No deficit 15 Anterior thoracic osteotomies Right lower extremity loss of SSEP after graft placement None No deficit 16 Posterior thoracolumbar decompression/fusion TLIF Right lower extremity loss MEP, SSEP stable None No deficit 17 Anterior cervical corpectomy and fusion No baseline SSEPs None Improved SSEPs 18 Posterior thoracolumbar decompression/fusion PSO Bilateral lower extremity SSEPs decreased with rod placement Rods placed, baseline SSEPs returned No deficit 19 T7 spinal cord tumor resection Loss of bilateral lower SSEPs (no MEPs present at baseline) None No change from preoperative function 20 Posterior then anterior cervicothoracic fusion Decreased SSEPs post flip None No deficit 21 Anterior thoracolumbar decompression/fusion Thoracotomy, left upper extremity (down arm) loss SSEPs Repositioned, large pt, procedure shortened Transient sensory changes 22 Posterior thoracolumbar decompression/fusion TLIF Right lower extremity loss of MEP Needle repositioned, signals reacquired No deficit 23 Posterior thoracic fusion Bilateral lower extremity loss of MEP with distraction Variable signal changes, returned to baseline No deficit 24 Posterio

Eager, Matthew; Jahangiri, Faisal; Shimer, Adam; Shen, Francis; Arlet, Vincent

2010-01-01

113

NMR imaging of the spine  

Energy Technology Data Exchange (ETDEWEB)

The usefulness of nuclear magnetic resonance (NMR) images in the evaluation of spinal disorders below the craniocervical junction was studied. Six normal subjects and 41 patients with various spinal abnormalities were examined. NMR proved capable of demonstrating important normal and pathologic anatomic structures; it was useful in the evaluation of syringohydromyelia and cystic spinal cord tumors, and the bright signal intensity of lipoma was quite impressive. In the evaluation of herniated disk, NMR images offered a new perspective by visualizing abnormal degradation of the signal intensity of the nucleus pulposus itself. NMR images were least valuable in the evaluation of spondylosis and spinal stenosis. Although NMR imaging of the spine is still in a very early developmental stage, the absence of both ionizing radiation and risks associated with contrast material makes it especially attractive as a new diagnostic method. This limited experience with currently available equipment suggests that, with technical refinement, the efficacy of NMR of the spine will increase.

Han, J.S. (Case Western Reserve Univ. School of Medicine, Cleveland, OH); Kaufman, B.; El Yousef, S.J.; Benson, J.E.; Bonstelle, C.T.; Alfidi, R.J.; Haaga, J.R.; Yeung, H.; Huss, R.G.

1983-12-01

114

NMR imaging of the spine  

International Nuclear Information System (INIS)

The usefulness of nuclear magnetic resonance (NMR) images in the evaluation of spinal disorders below the craniocervical junction was studied. Six normal subjects and 41 patients with various spinal abnormalities were examined. NMR proved capable of demonstrating important normal and pathologic anatomic structures; it was useful in the evaluation of syringohydromyelia and cystic spinal cord tumors, and the bright signal intensity of lipoma was quite impressive. In the evaluation of herniated disk, NMR images offered a new perspective by visualizing abnormal degradation of the signal intensity of the nucleus pulposus itself. NMR images were least valuable in the evaluation of spondylosis and spinal stenosis. Although NMR imaging of the spine is still in a very early developmental stage, the absence of both ionizing radiation and risks associated with contrast material makes it especially attractive as a new diagnostic method. This limited experience with currently available equipment suggests that, with technical refinement, the efficacy of NMR of the spine will increase

1983-01-01

115

Fetal evaluation of spine dysraphism  

International Nuclear Information System (INIS)

Spinal dysraphism or neural tube defects (NTD) encompass a heterogeneous group of congenital spinal anomalies that result from the defective closure of the neural tube early in gestation with anomalous development of the caudal cell mass. Advances in ultrasound and MRI have dramatically improved the diagnosis and therapy of spinal dysraphism and caudal spinal anomalies both prenatally and postnatally. Advances in prenatal US including high frequency linear transducers and three dimensional imaging can provide detailed information concerning spinal anomalies. MR imaging is a complementary tool that can further elucidate spine abnormalities as well as associated central nervous system and non-CNS anomalies. Recent studies have suggested that 3-D CT can help further assess fetal spine anomalies in the third trimester. With the advent of fetal therapy including surgery, accurate prenatal diagnosis of open and closed spinal dysraphism becomes critical in appropriate counselling and perinatal management. (orig.)

2010-06-01

116

MRI of the fetal spine  

International Nuclear Information System (INIS)

Magnetic resonance imaging of the fetal spine is a vital complement to fetal sonographic examination. Assessing the wide spectrum of spinal dysraphism, as well as spinal neoplasia, allows for more correct prenatal diagnoses, patient care planning, and patient counselling. Proper appraisal of the value of experimental procedures, such as fetal myelomeningocoele repair, requires a high level of diagnostic accuracy for the selection and follow-up of appropriate candidates. (orig.)

2004-09-01

117

Computed tomography of the spine  

International Nuclear Information System (INIS)

The book describes the computed tomographic (CT) techniques for imaging the different elements comprising the spinal column and canal. The use of intravenous and intrathecal contrast enhancement and of xenon enhancement is briefly mentioned. Reconstruction techniques and special problems regarding CT of the spine are presented. CT of the spinal cord, meninges and subarachnoid space, epidural space, intervertebral discs, facet joints, and vertebrae present normal anatomy, and several common pathologic conditions

1982-01-01

118

Percutaneous Transgastric Snaring for Repositioning of a Dislocated Internal Drain from a Pancreatic Pseudocyst  

International Nuclear Information System (INIS)

Pancreatic pseudocysts may occur in up to 10% of patients with acute or chronic pancreatitis. Symptomatic, persistent, and infected pancreatic pseudocysts require interventional therapy. We present the case of a patient with complete dislocation of a double pigtail catheter into an infected pseudocyst and the repositioning of the drainage catheter using a transgastric snaring technique. The combination of CT-guided percutaneous puncture and fluoroscopic snaring permitted minimally invasive management of this rare complication.

2008-07-01

119

Helmet Versus Active Repositioning for Plagiocephaly: A Three-Dimensional Analysis  

DEFF Research Database (Denmark)

BACKGROUND AND PURPOSE: Orthotic helmets and active repositioning are the most common treatments for deformational plagiocephaly (DP). Existing evidence is not sufficient to objectively inform decisions between these options. A three-dimensional (3D), whole-head asymmetry analysis was used to rigorously compare outcomes of these 2 treatment methods. PATIENTS AND METHODS: Whole-head 3D surface scans of 70 infants with DP were captured before and after treatment by using stereophotogrammetric imaging technology. Helmeted (n = 35) and nonhelmeted/actively repositioned (n = 35) infants were matched for severity of initial deformity. Surfaces were spatially registered to a symmetric template, which was deformed to achieve detailed right-to-left point correspondence for every point on the head surface. A ratio-metric asymmetry value was calculated for each point relative to its contralateral counterpart. Maximum and mean asymmetry values were determined. Change in mean and maximum asymmetry with treatment was the basis for group comparison. RESULTS: The helmeted group had a larger reduction than the repositioned group in both maximum (4.0% vs 2.5%; P = .02) and mean asymmetry (0.9% vs 0.5%; P = .02). The greatest difference was localized to the occipital region. CONCLUSIONS: Whole-head 3D asymmetry analysis is capable of rigorously quantifying the relative efficacy of the 2 common treatments of DP. Orthotic helmets provide statistically superior improvement in head symmetry compared with active repositioning immediately after therapy. Additional studies are needed to (1) establish the clinical significance of these quantitative differences in outcome, (2) define what constitutes pathologic head asymmetry, and (3) determine whether superiority of orthotic treatment lasts as the child matures. Pediatrics 2010;126:e936-e945

Lipira, A.B.; Gordon, S.

2010-01-01

120

The repositioning Nance appliance: a fixed functional appliance and case report  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Functional appliances are primarily orthopaedic tools used to influence the facial skeleton in a growing child. These appliances may be fixed or removable. A fixed functional appliance referred to as the Repositioning Nance Appliance (RNA) was developed and a case report is presented. The RNA is a fixed functional appliance consisting of bands on the upper first molars joined together with a 0.036-inch stainless steel wire that is bent around the anterior contour of the palate. Just lingual t...

Dawjee, S. M.; Khan, M. I.; Hlongwa, P.

2009-01-01

 
 
 
 
121

Serial repositioning of a Guenther tulip retrievable inferior vena cava filter in a pediatric patient  

Energy Technology Data Exchange (ETDEWEB)

We report an 11-year-old boy who required inferior vena cava (IVC) filtration for a prolonged period of time. A retrievable IVC filter was placed and repositioned three times, providing a total of 60 days of IVC filtration. The filter was removed when his risk of pulmonary embolus had decreased substantially. This is a relatively uncommon practice in the pediatric population. The technique is presented, and the available literature is reviewed. (orig.)

Haider, Ehsan A.; Rosen, J. Choi; Torres, Carlos; Valenti, David A. [McGill University Health Center, Department of Radiology, Montreal, QC (Canada)

2005-11-01

122

Variables Affecting Canalith Repositioning Maneuver (CRM) Trend for Treating Patients with Benign Paroxysmal Positional Vertigo (BPPV)  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Background: The purpose of this study was to identify variables affecting outcome in patients with benign paroxysmal positional vertigo (BPPV) treated with canalith repositioning maneuver (CRM). Methods: This interventional study was conducted on 58 patients (14 males, 44 females, mean age 48.12+13.22) referred to the Vertigo Rehabilitation Clinic of the Rehabilitation School of Tehran University of Medical Sciences from 2002 to 2004. All patients were treated with CRM. According to the treat...

Adel Ghahraman, M.; Hajiabolhassan, F.; Naraghi, M.; Sedaei, M.; Entezari, E.; Haddadi Avval, M.; Kamali, P.

2006-01-01

123

The comparison of cervical repositioning errors according to smartphone addiction grades.  

Science.gov (United States)

[Purpose] The purpose of this study was to compare cervical repositioning errors according to smartphone addiction grades of adults in their 20s. [Subjects and Methods] A survey of smartphone addiction was conducted of 200 adults. Based on the survey results, 30 subjects were chosen to participate in this study, and they were divided into three groups of 10; a Normal Group, a Moderate Addiction Group, and a Severe Addiction Group. After attaching a C-ROM, we measured the cervical repositioning errors of flexion, extension, right lateral flexion and left lateral flexion. [Results] Significant differences in the cervical repositioning errors of flexion, extension, and right and left lateral flexion were found among the Normal Group, Moderate Addiction Group, and Severe Addiction Group. In particular, the Severe Addiction Group showed the largest errors. [Conclusion] The result indicates that as smartphone addiction becomes more severe, a person is more likely to show impaired proprioception, as well as impaired ability to recognize the right posture. Thus, musculoskeletal problems due to smartphone addiction should be resolved through social cognition and intervention, and physical therapeutic education and intervention to educate people about correct postures. PMID:24764641

Lee, Jeonhyeong; Seo, Kyochul

2014-04-01

124

Visual servoing for intraoperative positioning and repositioning of mobile C-arms.  

Science.gov (United States)

The problem of positioning mobile C-arms, e.g. for down the beam techniques, as well as repositioning during surgical procedures currently requires time, skill and additional radiation. This paper uses a Camera-Augmented Mobile C-arm (CAMC) to speed up the procedure, simplify its execution and reduce the necessary radiation. For positioning the C-arm in down-the-beam position, the pre-operative diagnostic CT is used for defining the axis. Additional CT visible markers on patient's skin allow the CAMC's optical camera to compute the C-arm's pose and its required displacement for positioning. In the absence of electronically controlled mobile C-arms, the system provides step-by-step guidance to surgical staff until the final position is achieved. At this point, the surgeon can acquire an X-ray to ensure the correct positioning. In the case of intra-operative repositioning, no pre-operative CT is required. X-ray/Optical markers allow the visual servoing algorithm to guide the surgical staff in C-arm repositioning using CAMC's optical camera. This work paves the path for many possible applications of visual servoing in C-arm positioning and in surgical navigation. Experiments on phantom and a cadaver study demonstrate the advantages of the new methods. PMID:17354934

Navab, Nassir; Wiesner, Stefan; Benhimane, Selim; Euler, Ekkehard; Heining, Sandro Michael

2006-01-01

125

A Node Flow Model for the Inflexible Visitation Liner Shipping Fleet Repositioning Problem with Cargo Flows  

DEFF Research Database (Denmark)

We introduce a novel, node flow based mathematical model for the fixed-time version of a central problem in the liner shipping industry called the Liner Shipping Fleet Repositioning Problem (LSFRP). We call this version of the problem the Inflexible Visitation LSFRP (IVLSFRP). During repositioning, ves- sels are moved between routes in a liner shipping network. Shipping lines wish to reposition vessels as cheaply as possible without disrupting the cargo flows of the network. The LSFRP is characterized by chains of interacting activities with a multi-commodity flow over paths defined by the activities chosen. We intro- duce two versions of a node flow based model that exploit the fixed activity times of the IVLSFRPâ??s graph to handle cargo demands on the nodes of the graph, in- stead of the arcs, significantly reducing the number of variables. Using this model in CPLEX, we are able to solve 12 previously unsolved IVLSFRP instances to optimality. Additionally, we improve the solution time on every instance in the IVLSFRP dataset, sometimes by several orders of magnitude.

Tierney, Kevin; Jensen, Rune Møller

126

Temporomandibular joint disc repositioning using bone anchors: an immediate post surgical evaluation by Magnetic Resonance Imaging  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Open joint procedures using bone anchors have shown clinical and radiograph good success, but post surgical disc position has not been documented with MRI imaging. We have designed a modified technique of using two bone anchors and 2 sutures to reposition the articular discs. This MRI study evaluates the post surgical success of this technique to reposition and stabilize the TMJ articular discs. Methods Consecutive 81 patients with unilateral TMJ internal derangement (ID (81 TMJs were treated between December 1, 2003, and December 1, 2006, at the Department of Oral and Maxillofacial Surgery, Ninth Peoples Hospital, Shanghai, Jiao Tong University School of Medicine. All patients were subjected to magnetic resonance imaging before and one to seven days post surgery to determine disc position using the modified bone anchor technique. Results Postoperative MRIs (one to seven days confirm that 77 of 81 joints were identified as excellent results and one joint was considered good for an overall effective rate of 96.3% (78 of 81 joints. Only 3.7% (3 of 81 of the joints were designated as poor results requiring a second open surgery. Conclusions This procedure has provided successful repositioning of the articular discs in unilateral TMJ ID at one to seven days post surgery.

Haddad Majd S

2010-11-01

127

Use-dependent inhibition of dendritic spines  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Dendritic spines are now known to be subject to use-dependent plasticity that affects both their structure and their numbers. Recently, it has been demonstrated that a use-dependent increase in the density of dendritic spines occurs in both excitatory and inhibitory synapses in the mouse barrel cortex. Furthermore, it has been shown that although this increase in the density of spines and excitatory synapses is transient, the increase in spinous inhibitory synapses is long-lasting. These find...

Keller, Asaf

2002-01-01

128

Chondrosarcoma of the Mobile Spine and Sacrum  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Chondrosarcoma is a rare malignant tumor of bone. This family of tumors can be primary malignant tumors or a secondary malignant transformation of an underlying benign cartilage tumor. Pain is often the initial presenting complaint when chondrosarcoma involves the spine. In the mobile spine, chondrosarcoma commonly presents within the vertebral body and shows a predilection for the thoracic spine. Due to the resistance of chondrosarcoma to both radiation and chemotherapy, treatment is focuse...

Stuckey, Ryan M.; Marco, Rex A. W.

2011-01-01

129

Unintentional conversion of benign paroxysmal positional vertigo caused by repositioning procedures for canalithiasis: transitional BPPV.  

Science.gov (United States)

BPPV when diagnosed before any repositioning procedure is called primary BPPV. Primary BPPV canalithiasis treatment with repositioning procedures sometimes results in unintentional conversion of BPPV form: transitional BPPV. Objectives were to find transitional BPPV forms, how they influence relative rate of canal involvement and how to be treated. This study is a retrospective case review performed at an ambulatory, tertiary referral center. Participants were 189 consecutive BPPV patients. Main outcome measures were detection of transitional BPPV, outcome of repositioning procedures for transitional canalithiasis BPPV and spontaneous recovery for transitional cupulolithiasis BPPV. Canal distribution of primary BPPV was: posterior canal (Pc): 85.7% (162/189), horizontal canal (Hc): 11.6% (22/189), anterior canal (Ac): 2.6% (5/189); taken together with transitional BPPV it was: Pc: 71.3% (164/230), Hc: 26.5% (61/230), Ac: 2.2% (5/230). Transitional BPPV forms were: Hc canalithiasis 58% (24/41), Hc cupulolithiasis 37% (15/41) and common crux reentry 5% (2/41). Treated with barbecue maneuver transitional Hc canalithiasis cases either resolved in 58% (14/24) or transitioned further to transitional Hc cupulolithiasis in 42% (10/24). In follow-up of transitional Hc cupulolithiasis we confirmed spontaneous recovery in 14/15 cases in less than 2 days. The most frequent transitional BPPV form was Hc canalithiasis so it raises importance of barbecue maneuver treatment. Second most frequent was transitional Hc cupulolithiasis which very quickly spontaneously recovers and does not require any intervention. The rarest found transitional BPPV form was common crux reentry which is treated by Canalith repositioning procedure. Transitional BPPV taken together with primary BPPV may decrease relative rate of Pc BPPV, considerably increase relative rate of Hc BPPV and negligibly influence relative rate of Ac BPPV. Transitional BPPV forms can be produced by repositioning maneuvers (transitional Hc cupulolithiasis) or by the subsequent controlling positional test (transitional Hc canalithiasis and common crux reentry); underlying mechanisms are discussed. PMID:23605245

Babic, Borivoj B; Jesic, Snezana D; Milovanovic, Jovica D; Arsovic, Nenad A

2014-05-01

130

49 CFR 572.9 - Lumbar spine, abdomen, and pelvis.  

Science.gov (United States)

... 2010-10-01 2010-10-01 false Lumbar spine, abdomen, and pelvis. 572.9...DEVICES 50th Percentile Male § 572.9 Lumbar spine, abdomen, and pelvis. (a) The lumbar spine, abdomen, and pelvis consist...

2010-10-01

131

The etiology of missed cervical spine injuries.  

Science.gov (United States)

Missed or delayed diagnosis of cervical spine (C-spine) injuries may lead to extension of those injuries and subsequent preventable mortality or morbidity. Previous reports examining the incidence of missed C-spine injuries have not determined the nature of the causal clinical errors made or the extent to which these errors are avoidable. This study was undertaken to (1) determine the incidence of delayed or missed diagnosis of C-spine injuries and the consequences of those missed injuries; (2) define the clinical errors leading to the delays; and (3) to determine if these errors are the result of fundamental problems or a lack of advanced diagnostic skills or equipment. Between August 1985 and February 1991, 32,117 trauma patients were admitted to one of the six trauma centers in San Diego county. Cervical spine injuries were identified in 740 patients and the diagnosis was delayed or missed in 34 patients (4.6%). Ten of the 34 patients (29%) developed permanent sequelae as a result of these delays. The single most common error was the failure to obtain an adequate series of C-spine roentgenograms. Delayed diagnosis could have been avoided in at least 31 of 34 injuries by the appropriate use of a standard three-view C-spine series and careful interpretation of those roentgenograms. Patients at risk for C-spine injuries require a technically adequate three-view C-spine series and skilled radiographic interpretation. Cervical spine precautions should be maintained, particularly in high risk patients, until appropriate and expert review of the cervical spine roentgenograms can be obtained. PMID:8483172

Davis, J W; Phreaner, D L; Hoyt, D B; Mackersie, R C

1993-03-01

132

Quantitative digital radiography versus dual photon absorptiometry of the lumbar spine.  

Science.gov (United States)

Lumbar spine bone mineral density (BMD) was measured by quantitative digital radiography, a new dual energy x-ray technique, and by 153Gd dual photon absorptiometry (DPA) in 85 patients. Each patient was measured twice by the new method and once by DPA on the same day, with repositioning between measurements. Serial measurements were made on an hydroxyapatite spine phantom embedded in tissue-equivalent plastic to evaluate the long term reproducibility of each instrument. The spinal BMD measurements with the 2 techniques were linearly related and highly correlated (r = 0.98) over a range from severely osteopenic to high normal. This correlation was not affected by the age, weight, or BMD of the patient measured. Quantitative digital radiography's long-term reproducibility using the spine phantom was stable for 180 days (coefficient of variation, 0.23%); DPA values were 3 times as variable for 170 days (coefficient of variation 0.73%) and increased 1.0% (P less than 0.0001) after a software change. The short term reproducibility of quantitative digital radiography, estimated from paired patient measurements, was 2-fold better than reported values for DPA and was independent of the patient's age, weight, or BMD. Measurement time by quantitative digital radiography was 5-8 min, with a maximum radiation exposure of 3 mrem, significantly lower than the corresponding DPA values. Quantitative digital radiography's image resolution was superior to that of DPA, enabling it to measure more bones. These advantages along with the elimination of 153Gd source changes and Nuclear Regulatory Commission licensing requirements indicate that quantitative digital radiography is the superior method for spinal BMD measurements. PMID:3417851

Kelly, T L; Slovik, D M; Schoenfeld, D A; Neer, R M

1988-10-01

133

Anatomy and radiology of the sellar spine  

International Nuclear Information System (INIS)

Five anatomical and radiological observations of a spine protruding into the pituitary fossa are reported. This osseous spine, about 4 mm long, arises in the midline from the inferior part of the anterior aspect of the dorsum sellae and extends upward and forward. The possible origins of this malformation are discussed. (orig.)

1981-01-01

134

Primary osteogenic sarcoma of the spine  

International Nuclear Information System (INIS)

Primary osteogenic sarcoma of the spine is a rare tumor making up 0.85% to 2.0% of all osteogenic sarcomas. The majority (29/41) of previously reported cases have occurred in vertebrae affected by Paget disease or radiation exposure. Two cases of osteogenic sarcoma of the spine, one lumbar, the other thoracic, with no known predisposing factors are presented. (orig.)

1984-11-01

135

Gorham`s disease of the spine  

Energy Technology Data Exchange (ETDEWEB)

Massive osteolysis is a rare condition and is very uncommon in the spine. The MRI appearance of Gorham`s disease of the spine has not previously been reported. We present here a case of this condition with imaging details. (orig.)

Livesley, P.J. [The Royal National Orthopaedic Hospital Trust, Stanmore (United Kingdom); Saifuddin, A. [The Royal National Orthopaedic Hospital Trust, Stanmore (United Kingdom); Webb, P.J. [The Royal National Orthopaedic Hospital Trust, Stanmore (United Kingdom); Mitchell, N. [The Royal National Orthopaedic Hospital Trust, Stanmore (United Kingdom); Ramani, P. [The Royal National Orthopaedic Hospital Trust, Stanmore (United Kingdom)

1996-05-01

136

Lateral extracavitary approach to spine  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction. This paper describes the lateral extracavitary approach to the lumbar spine using the three­quarter prone position. Owing to unsatisfied results of the posterior approaches to spine in patients with the ventral compressive lesions, many ventral approaches as well as lateral extracavitary approach have been developed. Case Outline. A patient with tumor (chordoma of L3 vertebral body was operated on by means of ventral compression of cauda equina; the tumor had paraspinal propagation. Lateral extracavitary approach was used with a patient in three­quarter prone position, and corpectomy with the anterior stabilisation was performed followed by posterior transpedicular stabilisation through the same approach. Complete tumor removal and excellent neurological improvement were achieved. Conclusion. This approach provides safe ventral decompression of the spinal cord; it also enables the anterior and posterior instrumental stabilisation through the same incision and in the same position during the intervention. The three­quarter prone position allows excellent view of the dural sac.

Iveti? Dražen

2013-01-01

137

Accessory spine of the foramen ovale.  

Science.gov (United States)

The objective of this study was to provide morphometric analysis of an accessory spine that was found within the lumen of the foramen ovale, as well as to find out whether this structure could mechanically irritate the mandibular nerve. A bifid spine was perceived in the macerated skull of an adult individual. It was located in the anterior part of the left foramen ovale. The overall length of the spine was found to be 1.8 mm. The spine had a homogenous structure, and showed high levels of mineralisation. We conclude that the accessory spine did not compress the mandibular nerve, and that the foramen ovale provided enough space for passage of the nerve. In all likelihood, these structures remained in anatomical accordance without causing any neurological symptoms. PMID:23197146

Skrzat, J; Walocha, J; Zawili?ski, J

2012-11-01

138

Sport injuries of the cervical spine  

International Nuclear Information System (INIS)

The article reports on injuries of the cervical spine occurring during sports activities. An attempt is made to reconstruct the movements which led to the cervical spine injuries in question. In two cases of accidents occuring during bathing, one football accident and a toboggan accident, the injuries concerned point to hyperextension of the cervical spine as cause of the injury. In another football accident and a riding accident, the changes observed allow us to conclude that the movement leading to the injury must have been a hyperflexion. One accident occurring while jumping on the trampolin resulted in an injury of the upper cervical spine pointing to the action of a compressive force on the cervical spine in addition to the force resulting in hyperflexion. (orig.)

1981-01-01

139

Surgical repositioning of intruded immature permanent incisor: An updated treatment concept  

Directory of Open Access Journals (Sweden)

Full Text Available Intrusion of immature permanent anterior teeth presents a great dilemma due to variety of treatment options. The ideal treatment option is the one with least probability of developing complications like external root resorption, obliteration of pulp canal, marginal bone loss etc. This paper presents a case report with treatment strategy of repositioning, splinting, successfully attempted apexification and obturation of a completely intruded immature permanent central incisor. Excellent healing with no post-operative complications even after 10 months of follow up.

Garg S

2008-10-01

140

Late Acceptance Hill Climbing for the Liner Shipping Fleet Repositioning Problem  

DEFF Research Database (Denmark)

Late Acceptance Hill Climbing (LAHC) has been shown to be an effective local search method for sev- eral types of optimization problems, such as on certain types of scheduling problems as well as the traveling salesman problem. We apply LAHC to a central prob- lem in the liner shipping industry, the Liner Shipping Fleet Repositioning Problem (LSFRP). The LSFRP in- volves the movement of vessels between routes in a liner shipping network subject to complex costs and timing restrictions. We show that despite LAHCâ??s promising performance on other problems, it is unable to achieve the performance of simulated annealing on the LSFRP.

Tierney, Kevin

 
 
 
 
141

Misplacement of a femoral venous catheter into the ascending lumbar vein: repositioning using ultrasonographic guidance.  

Science.gov (United States)

A 5-week-old infant with congenital chylothorax required long-term intravenous access for parenteral nutrition. Cannulation of the inferior vena cava via the left femoral vein was attempted, but the catheter was misplaced into the left ascending lumbar vein. Catheter removal is advised when such malposition is identified. We were able successfully to redirect the catheter into the inferior vena cava using ultrasonographic guidance. This procedure has not been described previously in children. We propose that repositioning of incorrectly placed vascular catheters can be achieved using ultrasound guidance at the bedside. PMID:11280642

Carrion, E; Hertzog, J H; Gunter, A W; Lu, T; Ruff, C; Hauser, G J

2001-01-01

142

Ultrasound guided spine needle insertion  

Science.gov (United States)

An ultrasound (US) guided, CT augmented, spine needle insertion navigational system is introduced. The system consists of an electromagnetic (EM) sensor, an US machine, and a preoperative CT volume of the patient anatomy. Three-dimensional (3D) US volume is reconstructed intraoperatively from a set of two-dimensional (2D) freehand US slices, and is coregistered with the preoperative CT. This allows the preoperative CT volume to be used in the intraoperative clinical coordinate. The spatial relationship between the patient anatomy, surgical tools, and the US transducer are tracked using the EM sensor, and are displayed with respect to the CT volume. The pose of the US transducer is used to interpolate the CT volume, providing the physician with a 2D "x-ray vision" to guide the needle insertion. Many of the system software components are GPU-accelerated, allowing real-time performance of the guidance system in a clinical setting.

Chen, Elvis C. S.; Mousavi, Parvin; Gill, Sean; Fichtinger, Gabor; Abolmaesumi, Purang

2010-03-01

143

Postoperative syndrome after spine surgery  

International Nuclear Information System (INIS)

Postoperative syndrome after spine surgery, i.e., symptoms or syndromes caused by complications or procedure-related consequences, is gaining more and more importance. Due to great improvements concerning imaging and operative techniques (microsurgery, instrumentation) the total number of spinal surgeries as well as their related complications are increasing. Procedure-related postoperative complications including neurological deficit syndromes can occur acutely or at a later date. Concerning imaging techniques for postoperative evaluation after spinal surgery there are several modalities available. Their indications depend on complex factors including initial pathology the surgery was performed for, kind of surgical technique (surgical approach, instrumentation), anatomy of the patient as well as the time between onset of symptoms and surgery. In cases of ambiguous findings, the combination of different imaging techniques can be instrumental. (orig.)

2006-06-01

144

Vascular malformations of the spine  

International Nuclear Information System (INIS)

The vascular malformations of the spine and spinal cord are rare diseases. Possible symptoms may consist in a transient neurological deficit, a progressive sensorimotor transverse lesion or an acute para- or tetraplegia. Damage to the spinal cord occurs by bleeding, space-occupying effects and venous congestion, rarely by steal effects. Classification of the true inborn malformations differentiates between arteriovenous malformations (AVMs), cavernomas and capillary teleangiectasias. The more frequent spinal dural arteriovenous fistula (SDAVF) of the elderly patient is a probably acquired lesion which is presented in a separate paper. Capillary teleangiectasias are mostly incidental findings but may cause differential diagnostic problems. Cavernomas are important causes of hemorrhage and may initially be obscured within the bleeding. MRI is the most relevant imaging procedure in the early diagnostic workup. In case of an AVM selective spinal angiography is required to define the type of the lesion and to decide about the appropriate therapy which may be endovascular-interventional, neurosurgical, combined or attentive. (orig.)

2001-11-01

145

Persistent Direction-Fixed Nystagmus Following Canalith Repositioning Maneuver for Horizontal Canal BPPV: A Case of Canalith Jam.  

Science.gov (United States)

The authors report a 64-year-old man who developed persistent direction fixed nystagmus after a canalith repositioning maneuver for horizontal canal benign paroxysmal positional vertigo (HC-BPPV). The patient was initially diagnosed with right HC-BPPV given that the Dix-Hallpike test showed geotropic horizontal nystagmus that was more pronounced on the right side, although the roll test did not show any positional nystagmus. The patient was treated with a canalith repositioning maneuver (Lempert maneuver). The next day, the patient experienced a different character of dizziness, and left-beating spontaneous nystagmus regardless of head position was observed. After a forced prolonged left decubitus and frequent head shaking, his symptoms and nystagmus resolved. This condition, referred to as canalith jam, can be a complication after the repositioning maneuver in patients with BPPV. Atypical positional tests suggest that abnormal canal anatomy could be the underlying cause of canalith jam. PMID:24917912

Chang, Young-Soo; Choi, Jeesun; Chung, Won-Ho

2014-06-01

146

Larval Zebrafish Model for FDA-Approved Drug Repositioning for Tobacco Dependence Treatment  

Science.gov (United States)

Cigarette smoking remains the most preventable cause of death and excess health care costs in the United States, and is a leading cause of death among alcoholics. Long-term tobacco abstinence rates are low, and pharmacotherapeutic options are limited. Repositioning medications approved by the U.S. Food and Drug Administration (FDA) may efficiently provide clinicians with new treatment options. We developed a drug-repositioning paradigm using larval zebrafish locomotion and established predictive clinical validity using FDA-approved smoking cessation therapeutics. We evaluated 39 physician-vetted medications for nicotine-induced locomotor activation blockade. We further evaluated candidate medications for altered ethanol response, as well as in combination with varenicline for nicotine-response attenuation. Six medications specifically inhibited the nicotine response. Among this set, apomorphine and topiramate blocked both nicotine and ethanol responses. Both positively interact with varenicline in the Bliss Independence test, indicating potential synergistic interactions suggesting these are candidates for translation into Phase II clinical trials for smoking cessation.

Cousin, Margot A.; Ebbert, Jon O.; Wiinamaki, Amanda R.; Urban, Mark D.; Argue, David P.; Ekker, Stephen C.; Klee, Eric W.

2014-01-01

147

Drug repositioning by applying 'expression profiles' generated by integrating chemical structure similarity and gene semantic similarity.  

Science.gov (United States)

Drug repositioning, also known as drug repurposing or reprofiling, is the process of finding new indications for established drugs. Because drug repositioning can reduce costs and enhance the efficiency of drug development, it is of paramount importance in medical research. Here, we present a systematic computational method to identify potential novel indications for a given drug. This method utilizes some prior knowledge such as 3D drug chemical structure information, drug-target interactions and gene semantic similarity information. Its prediction is based on another form of 'expression profile', which contains scores ranging from -1 to 1, reflecting the consensus response scores (CRSs) between each drug of 965 and 1560 proteins. The CRS integrates chemical structure similarity and gene semantic similarity information. We define the degree of similarity between two drugs as the absolute value of their correlation coefficients. Finally, we establish a drug similarity network (DSN) and obtain 33 modules of drugs with similar modes of action, determining their common indications. Using these modules, we predict new indications for 143 drugs and identify previously unknown indications for 42 drugs without ATC codes. This method overcomes the instability of gene expression profiling derived from experiments due to experimental conditions, and predicts indications for a new compound feasibly, requiring only the 3D structure of the compound. In addition, the high literature validation rate of 71.8% also suggests that our method has the potential to discover novel drug indications for existing drugs. PMID:24603772

Tan, Fujian; Yang, Ruizhi; Xu, Xiaoxue; Chen, Xiujie; Wang, Yunfeng; Ma, Hongzhe; Liu, Xiangqiong; Wu, Xin; Chen, Yuelong; Liu, Lei; Jia, Xiaodong

2014-05-01

148

Trauma: Conventional radiologic study in spine injury  

Energy Technology Data Exchange (ETDEWEB)

This book includes a discussion of the anatomy of the spinal cord and descriptions of methods for tailored radiologic investigation of spine trauma. Most of the text is devoted to the analysis and classification of spinal injury by radiologic signs and mode of injury. The author addresses injury to the entire spine but emphasizes the cervical spine. Plain radiography and conventional tomography are the only imaging methods discussed. The author stresses the active role of the attending radiologist in directing every phase of the x-ray study. Many subtle variations in patient positioning plus beam direction and angulation are described.

Dosch, J.

1985-01-01

149

Complication management with minimally invasive spine procedures.  

LENUS (Irish Health Repository)

Spine surgery as we know it has changed dramatically over the past 2 decades. More patients are undergoing minimally invasive procedures. Surgeons are becoming more comfortable with these procedures, and changes in technology have led to several new approaches and products to make surgery safer for patients and improve patient outcomes. As more patients undergo minimally invasive spine surgery, more long-term outcome and complications data have been collected. The authors describe the common complications associated with these minimally invasive surgical procedures and delineate management options for the spine surgeon.

Hussain, Namath S

2012-02-01

150

Gonadal dose reduction in lumbar spine radiography  

International Nuclear Information System (INIS)

Different ways to minimize the gonadal dose in lumbar spine radiography have been studied. Two hundred and fifty lumbar spine radiographs were reviewed to assess the clinical need for lateral L5/S1 projection. Modern film/screen combinations and gonadal shielding of externally scattered radiation play a major role in the reduction of the genetic dose. The number of exposures should be minimized. Our results show that two projections, anteroposterior (AP) and lateral, appear to be sufficient in routine radiography of the lumbar spine. (orig.)

1983-02-01

151

Bergmann glial ensheathment of dendritic spines regulates synapse number without affecting spine motility  

Digital Repository Infrastructure Vision for European Research (DRIVER)

In the cerebellum, lamellar Bergmann glial (BG) appendages wrap tightly around almost every Purkinje cell dendritic spine. The function of this glial ensheathment of spines is not entirely understood. The development of ensheathment begins near the onset of synaptogenesis, when motility of both BG processes and dendritic spines are high. By the end of the synaptogenic period, ensheathment is complete and motility of the BG processes decreases, correlating with the decreased motility of dendri...

Lippman Bell, Jocelyn J.; Lordkipanidze, Tamar; Cobb, Natalie; Dunaevsky, Anna

2010-01-01

152

A method for articulating and displaying the human spine.  

Science.gov (United States)

An inexpensive and effective method for articulating a dry human spine is described. By constructing a Styrofoam spine tray, analysts can now accurately position and align each vertebra in correct anatomical order, allow for gaps because of missing vertebrae, and lay out the spine for documentation and photography. The spine tray provides analysts with a quick, easy, and professional quality method for aligning and orienting the human spine in the field and laboratory. PMID:19732275

Mann, Robert W

2009-11-01

153

THE SPINE OF THE COSMIC WEB  

International Nuclear Information System (INIS)

We present the SpineWeb framework for the topological analysis of the Cosmic Web and the identification of its walls, filaments, and cluster nodes. Based on the watershed segmentation of the cosmic density field, the SpineWeb method invokes the local adjacency properties of the boundaries between the watershed basins to trace the critical points in the density field and the separatrices defined by them. The separatrices are classified into walls and the spine, the network of filaments and nodes in the matter distribution. Testing the method with a heuristic Voronoi model yields outstanding results. Following the discussion of the test results, we apply the SpineWeb method to a set of cosmological N-body simulations. The latter illustrates the potential for studying the structure and dynamics of the Cosmic Web.

2010-11-01

154

The Spine of the Cosmic Web  

Science.gov (United States)

We present the SpineWeb framework for the topological analysis of the Cosmic Web and the identification of its walls, filaments, and cluster nodes. Based on the watershed segmentation of the cosmic density field, the SpineWeb method invokes the local adjacency properties of the boundaries between the watershed basins to trace the critical points in the density field and the separatrices defined by them. The separatrices are classified into walls and the spine, the network of filaments and nodes in the matter distribution. Testing the method with a heuristic Voronoi model yields outstanding results. Following the discussion of the test results, we apply the SpineWeb method to a set of cosmological N-body simulations. The latter illustrates the potential for studying the structure and dynamics of the Cosmic Web.

Aragón-Calvo, Miguel A.; Platen, Erwin; van de Weygaert, Rien; Szalay, Alexander S.

2010-11-01

155

Transverse axial tomography of the spine.  

Science.gov (United States)

Transerse axial tomography is a technique by which the spine is viewed radiographically in cross section. The tomographic apparatus, technique of examination, and radiation exposure will be discussed. Examples of normal and pathologic anatomy of the cervical, thoracic, and lumbar spine will be presented. In the lumbar spine cross-sectional views of stenotic canals due to facetal hypertrophy, congenital stenosis, spondylolithesis, and ventral overgrowth of spine fusions will be demonstrated. Measurements of the sagittal and interpedicular distances on conventional x-rays have correlated poorly with the anatomic state in lumbar stenosis. A high degree of correlation has been demonstrated by plotting the cross-sectional area configuration of the bony canal, as well as a new measurement, the interfacet distance, on axial tomograms. Transverse axial tomography is an exciting, new approach in neuroradiology for the evaluation of spinal disorders which have primarily axial distortion. PMID:791576

Gargano, F P

1976-12-01

156

Biostratigraphy of Echinoid spines, Cretaceous of Texas  

Energy Technology Data Exchange (ETDEWEB)

Echinoid (sea urchin) spines from Cretaceous strata have widely varying morphology. They are common, and most are small enough to be recovered from well cuttings. Many forms have restricted ranges; consequently, echinoid spine have substantial biostratigraphic utility. There have been established 115 form taxa of echinoid spines and 14 form taxa of ophiuroid-asteroid spines for the Cretaceous of Texas. The specimens used for establishing the form taxa were processed from 533 outcrop samples (78 localities) from 30 Cretaceous formations, each with a well-defined age based on faunal zones of ammonites and Foraminifera. A dichotomous key in 9 parts and a catalog of scanning electron micrographs (87 plates) have been set up to assist identification of the form taxa. Range charts for the echinoid and ophiuroid-asteroid form taxa have utility through the Cretaceous of much of the Gulf Coastal area. The most precise zonation has been possible for the Albian.

Kirkland, P.L.

1984-04-01

157

Cactus Spines in Tongues of Slaughtered Cattle.  

Science.gov (United States)

The damage caused by cactus spines predisposes the tongue to bacterial infection, leading to focal suppurative granulomas. The microscopic findings in these granulomas, which contain rosettes, are not unlike those associated with infection by Actinobacill...

G. Migaki L. E. Hinson G. D. Imes F. M. Garner

1969-01-01

158

Congenital block vertebrae in lumbar spine  

Digital Repository Infrastructure Vision for European Research (DRIVER)

A 34-year-old female visited our rheumatology clinic with the complaint of non-inflammatory back pain that usually occurred on bending down and radiated to bilateral lower limbs. A diagnosis of compressive neuropathy was suspected and an initially performed digital X-ray of lumbar spine revealed a rare congenital anomaly termed as ‘Congenital block vertebrae’ in the lumbar spine (Fig 1).Block vertebrae, a congenital anomaly, occurs due to improper segmentation of vertebral column during f...

2013-01-01

159

Computed tomography of the sellar spine  

International Nuclear Information System (INIS)

The authors report the CT scan findings in a case of sellar spine. This osseous spine which arises on the midline of the anterior aspect of the dorsum sellae and is directed toward the center of the sella turcica has already been described on specimens and on plain films but never on CT scans. The CT scan findings confirm the normal appearance of the surrounding structures. (orig.)

1983-01-01

160

Rigid spine syndrome : a noninvasive cardiac evaluation  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Rigid spine syndrome (RSS) is a group of childhood-onset muscle disorders characterized by marked limitation of flexion of the spine. Various cardiac changes have been documented in case reports. This study reports on a cardiac evaluation of nine patients with the “vacuolar variant” of RSS. Noninvasive cardiac evaluation entailed creatine kinase levels, full-inspiration chest roentgenograms, standard 12-lead ECG, and 24-h ambulatory ECG recording, as well as M-mode and two-dimensional ec...

Stubgen, Joerg-patrick

2008-01-01

 
 
 
 
161

Complexity of the thoracic spine pedicle anatomy  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Transpedicular screw fixation provides rigid stabilization of the thoracolumbar spine. For accurate insertion of screws into the pedicles and to avoid pedicle cortex perforations, more precise knowledge of the anatomy of the pedicles is necessary. This study was designed to visualize graphically the surface anatomy and internal architecture of the pedicles of the thoracic spine. Fifteen vertebrae distributed equally among the upper, middle, and lower thoracic regions were used. For the purpos...

Panjabi, M. M.; O Holleran, J. D.; Crisco, J. J.; Kothe, R.

1997-01-01

162

Posteroanterior versus anteroposterior lumbar spine radiology  

International Nuclear Information System (INIS)

The posteroanterior view of the lumbar spine has important features including radiation protection and image quality; these have been studied by various investigators. Investigators have shown that sensitive tissues receive less radiation dosage in the posteroanterior view of the spine for scoliosis screening and intracranial tomography without altering the image quality. This paper emphasizes the importance of the radiation safety aspect of the posteroanterior view and shows the improvement in shape distortion in the lumbar vertebrae

1990-01-01

163

Posteroanterior versus anteroposterior lumbar spine radiology.  

Science.gov (United States)

The posteroanterior view of the lumbar spine has important features including radiation protection and image quality; these have been studied by various investigators. Investigators have shown that sensitive tissues receive less radiation dosage in the posteroanterior view of the spine for scoliosis screening and intracranial tomography without altering the image quality. This paper emphasizes the importance of the radiation safety aspect of the posteroanterior view and shows the improvement in shape distortion in the lumbar vertebrae. PMID:2338520

Tsuno, M M; Shu, G J

1990-01-01

164

Posteroanterior versus anteroposterior lumbar spine radiology  

Energy Technology Data Exchange (ETDEWEB)

The posteroanterior view of the lumbar spine has important features including radiation protection and image quality; these have been studied by various investigators. Investigators have shown that sensitive tissues receive less radiation dosage in the posteroanterior view of the spine for scoliosis screening and intracranial tomography without altering the image quality. This paper emphasizes the importance of the radiation safety aspect of the posteroanterior view and shows the improvement in shape distortion in the lumbar vertebrae.

Tsuno, M.M.; Shu, G.J. (Cleveland Chiropractic College, Los Angeles, CA (USA))

1990-03-01

165

Neuroimaging for spine and spinal cord surgery  

International Nuclear Information System (INIS)

Recent advances in neuroimaging of the spine and spinal cord are described based upon our clinical experiences with spinal disorders. Preoperative neuroradiological examinations, including magnetic resonance (MR) imaging and computerized tomography (CT) with three-dimensional reconstruction (3D-CT), were retrospectively analyzed in patients with cervical spondylosis or ossification of the posterior longitudinal ligament (130 cases), spinal trauma (43 cases) and intramedullary spinal cord tumors (92 cases). CT scan and 3D-CT were useful in elucidating the spine pathology associated with degenerative and traumatic spine diseases. Visualization of the deformity of the spine or fracture-dislocation of the spinal column with 3D-CT helped to determine the correct surgical treatment. MR imaging was most important in the diagnosis of both spine and spinal cord abnormalities. The axial MR images of the spinal cord were essential in understanding the laterality of the spinal cord compression in spinal column disorders and in determining surgical approaches to the intramedullary lesions. Although non-invasive diagnostic modalities such as MR imaging and CT scans are adequate for deciding which surgical treatment to use in the majority of spine and spinal cord disorders, conventional myelography is still needed in the diagnosis of nerve root compression in some cases of cervical spondylosis. (author)

2001-01-01

166

Development and validation of a strategic repositioning model for defense and aerospace contractors  

Science.gov (United States)

Strategic repositioning refers to the organized efforts of defense contractors to "reposition" a technology that they have developed for a defense sector customer into a civilian or commercial market. The strategic repositioning model developed here is a structural model: it seeks to isolate the factors that influence choice of strategy, which in turn influences the organization's performance. The model draws from the prior experience of contractors (through interviews and surveys) and companies in other sectors (through a review of the relevant published research). (1) Over all, the model accounted for 55% of the variance in financial performance of the sample and 35% for the underlying population. (2) Key success factors include a rigorous planning process, a target market in the growth (vs. incubation) stage, a priority on market leadership as well as financial return, the ability to operate in an ambiguous business environment, and a relatively short time horizon but strong corporate support. (3) The greatest challenges that a contractor is likely to encounter are understanding his new customers' buying practices, strong competition, and adapting his technology to their needs and price expectations. (4) To address these issues contractors often involve partners in their entry strategy, but partnerships of equals tend to be more difficult to bring off than direct entry strategies. (5) The two major target market categories--government and commercial--present different challenges. Commercial customers are more likely to resist doing business with the contractor, while contractors entering government and other noncommercial markets are more likely to encounter price resistance, low technical sophistication among customers, and difficulties reaching their customer base. (6) Despite these differences across markets, performance is not influenced by the target market category, nor by the type of product or service or the contractor's functional orientation (marketing, technology, or operations). (7) The absence of a difference in performance may be partly due to natural selection. Noncommercial markets tend to attract contractors with more deliberative, consultative, and process-oriented corporate cultures, while commercial markets tend to attract contractors with results-oriented, opportunistic cultures.

Bers, John A.

167

Cardiac resynchronization by repositioning of a ventricular epicardial lead in a patient with hypoplastic left heart syndrome.  

Science.gov (United States)

Patients with congenital heart disease and univentricular circulation are vulnerable to ventricular dysfunction. In the context of atrioventricular conduction defects, a ventricular pacemaker may be placed, possibly introducing dyssynchronous wall motion and deterioration of ventricular pump function. We describe such a case in which repositioning of the ventricular lead restored synchronicity. PMID:23052668

Odland, Hans Henrik; Brun, Henrik; Saatvedt, Kjell; Kongsgård, Erik

2013-12-01

168

Collar spine models in the genus Echinostoma (Trematoda: Echinostomatidae).  

Science.gov (United States)

This paper discusses collar spine arrangements in the genus Echinostoma. All arrangements are of uneven numbers of collar spines on the oral collar. The total number of collar spines in these arrangements ranges from a low 31 to a high 51. There are 11 models of collar spine arrangements in the Echinostoma consisting of spine numbers 31, 33, 35, 37, 39, 41, 43, 45, 47, 49, and 51. Representative species with these collar spine arrangements are given in the article. The number of collar spines in a species is identical in both the larval and adult forms. Reports of even numbered spine counts in the genus Echinostoma are erroneous and probably reflect counts on worms with lost, retracted, or supernumerary spines. PMID:19468754

Kanev, Ivan; Fried, Bernard; Radev, Valentin

2009-10-01

169

Repositioning accuracy of a noninvasive head fixation system for stereotactic radiotherapy  

Energy Technology Data Exchange (ETDEWEB)

We report on the repositioning accuracy of patient setup achieved with a noninvasive head fixation device for stereotactic radiotherapy. A custom head mask which attaches to our stereotactic radiosurgery head ring assembly is fabricated for each patient. The position and orientation of a patient in the stereotactic space at the time of treatment are determined from analyzing portal films containing images of radio-opaque spheres embedded in a custom mouthpiece. From analysis of 104 setups of 12 patients, we find that the average distance between the treated isocenter and its mean position is 1.8 mm, and that the standard deviations of the position of the treated isocenter in stereotactic coordinate space about its mean position are less than 1.4 mm in translation in any direction and less than 1{degree} of rotation about any axis. {copyright} {ital 1996 American Association of Physicists in Medicine.}

Hamilton, R.J.; Kuchnir, F.T.; Pelizzari, C.A.; Sweeney, P.J.; Rubin, S.J. [The University of Chicago, Department of Radiation and Cellular Oncology, 5841 S. Maryland Avenue MC 0085, Chicago, Illinois 60637 (United States)

1996-11-01

170

Actin-dependent intranuclear repositioning of an active gene locus in vivo  

Science.gov (United States)

Although bulk chromatin is thought to have limited mobility within the interphase eukaryotic nucleus, directed long-distance chromosome movements are not unknown. Cajal bodies (CBs) are nuclear suborganelles that nonrandomly associate with small nuclear RNA (snRNA) and histone gene loci in human cells during interphase. However, the mechanism responsible for this association is uncertain. In this study, we present an experimental system to probe the dynamic interplay of CBs with a U2 snRNA target gene locus during transcriptional activation in living cells. Simultaneous four-dimensional tracking of CBs and U2 genes reveals that target loci are recruited toward relatively stably positioned CBs by long-range chromosomal motion. In the presence of a dominant-negative mutant of ?-actin, the repositioning of activated U2 genes is markedly inhibited. This supports a model in which nuclear actin is required for these rapid, long-range chromosomal movements.

Dundr, Miroslav; Ospina, Jason K.; Sung, Myong-Hee; John, Sam; Upender, Madhvi; Ried, Thomas; Hager, Gordon L.; Matera, A. Gregory

2007-01-01

171

Automatic Thresholding for Frame-Repositioning Using External Tracking in PET Brain Imaging  

DEFF Research Database (Denmark)

Motion correction (MC) in positron emission tomography (PET) brain imaging become of higher importance with increasing scanner resolution. Several motion correction methods have been suggested and so far the Polaris Vicra tracking system has been the preferred one for motion registration. We present an automated algorithm for dividing PET acquisitions into subframes based on the registered head motion to correct for intra-frame motion with the frame repositioning MC method. The method is tested on real patient data (five 11C-SB studies and five 11C-PIB studies) and compared with an image based registration method (AIR). Quantitative evaluation was done using a correlation measure. The study shows that MC improves the correlation of the PET images and that AIR performed slightly better than the Polaris Vicra. We found significant intra-frame motion of 1-5 mm in 9 frames but the correlation was not significantly improved using intra-frame MC.

Olesen, Oline Vinter; Larsen, Rasmus

2010-01-01

172

Effect of Laminectomy on Stability of Lumbar Spine Effect of Laminectomy on Stability of Lumbar Spine  

Directory of Open Access Journals (Sweden)

Full Text Available The paper aims at the presentation of the lumbar spine finite element model used in a study of segmental kinematics including the tissue loading. Lumbar spine FE-model consisting of the three lumbar vertebras, two disc (including annulus and nucleus and vast variety of ligaments. The primary model objective is its verification by experimental test data obtained from cadaver spine segments. A confirmed model was used for a study of various range of laminectomy effect. On this model we simulate a various loading states witch can spine segment arrive at under physiologic conditions (compression, flexion, extension and lateral bending. FE-model could predict the laminectomy impact on the operation approach. The paper aims at the presentation of the lumbar spine finite element model used in a study of segmental kinematics including the tissue loading. Lumbar spine FE-model consisting of the three lumbar vertebras, two disc (including annulus and nucleus and vast variety of ligaments. The primary model objective is its verification by experimental test data obtained from cadaver spine segments. A confirmed model was used for a study of various range of laminectomy effect. On this model we simulate a various loading states witch can spine segment arrive at under physiologic conditions (compression, flexion, extension and lateral bending. FE-model could predict the laminectomy impact on the operation approach.

Petr Tichy

2009-12-01

173

Strategic repositioning: a practical approach to reducing costs and enhancing quality.  

Science.gov (United States)

Sharply increased competition threatens the status quo in most healthcare organizations, which must now decrease costs while improving service. Those organizations can use strategic repositioning to evaluate their business practices and insure that they are performing at peak efficiency. Strategic repositioning (SR) is a process that changes functions within an institution--not just how people do the jobs they have done, but what they do. Meaningful cost savings come from changing the way services are delivered rather than from simple belt-tightening. This article discusses initiatives that resulted from an SR process at the University of Pittsburgh Medical Center. The radiology department was one of the first departments to participate in the process and successfully reached its goal: to reduce its operating budget by 22% over three years while increasing service quality. Generally, SR includes the following steps: assessing the status quo, project organization, benchmarking and evaluating results. Some of the changes proposed by the radiology department were: closing outpatient radiology services at an adjacent clinic, decommissioning the CT scanner in the OR, PACS implementation, consolidating ultrasound with the peripheral vascular lab, decreasing the use of non-ionic contrast media, decommissioning underutilized equipment, and consolidating services such as transcription and scheduling. As changes are suggested with an SR process, executives must make difficult decisions, such as whether a program survives or is discontinued. Radiology cannot do this alone! Establishing ambitious improvement goals at the beginning will set the stage for the program. Stretch beyond the limit. If the expectation is to decrease 15%, try to decrease 20% and in many cases quality will still be enhanced. It can be done. PMID:10157203

Hanwell, L L

1996-01-01

174

Recurrent upside-down stomach after endoscopic repositioning and gastropexy treated by laparoscopic surgery.  

Science.gov (United States)

Patients with an upside-down stomach usually receive surgical treatment. In high-risk patients, endoscopic repositioning and gastropexy can be performed. However, the risk of recurrence after endoscopic treatment is not known. We treated a case of recurrent upside-down stomach after endoscopic therapy that indicated the limits of endoscopic treatment and risk of recurrence. An 88-year-old woman was treated three times for vomiting in the past. She presented to our hospital with periodic vomiting and an inability to eat, and a diagnosis of upside-down stomach was made. Endoscopic repositioning and gastropexy were performed. The anterior stomach wall was fixed to the abdominal wall in three places as widely as possible. Following treatment, she became symptom-free. Three months later, she was hospitalized again because of a recurrent upside-down stomach. Laparoscopic repair of hernias and gastropexy was performed. Using a laparoscope, two causes of recurrence were found. One cause was that the range of adherence between the stomach and the abdominal wall was narrow (from the antrum only to the lower corpus of stomach), so the upper corpus of stomach was rotated and herniated into the esophageal hiatus. The other cause was adhesion between the omentum and the esophageal hiatus which caused the stomach to rotate and repeatedly become herniated. Although endoscopic treatment for upside-down stomach can be a useful alternative method in high-risk patients, its ability to prevent recurrence is limited. Moreover, a repeated case caused by adhesions has risks of recurrence. PMID:24574947

Toyota, Kazuhiro; Sugawara, Yuji; Hatano, Yu

2014-01-01

175

The dynamics of spine density changes.  

Science.gov (United States)

Numerous papers have been published describing the effects of learning and environmental changes on the wiring of brain areas in mammals and birds. The density of dendritic spines, which can be taken as a measure of the complexity of a given neuronal network, has been shown to increase or to decrease depending on the experiment and on the brain area involved. Almost no information is available concerning the speed with which a given network reacts to learning events or environmental changes. We therefore examined the time course of spine density changes in two areas of the zebra finch forebrain, which have been shown previously to be either involved in sexual imprinting (LNH, lateral part of the neo-hyperstriatum) or to react to environmental changes (ANC, archi-neostriatum caudale). The decrease of spine density in LNH of zebra finch males after sexual imprinting is very fast, the new level of spine density is reached after 2 days. In contrast, decrease of spine density within ANC as a consequence of transferring birds from a social condition into isolation is very slow, lasting about 3 weeks. The increase of spine density within ANC after transfer of the males from isolation to a social condition occurs within 3 days. The differences in adaptation times cannot be due to limitations in the growth speed of single spines, because this has been shown to be much faster (hours instead of days). Instead, the speed of adaptation may be dependent on the availability of information about the final wiring diagram and on functional aspects like the energy demands for maintenance or alteration of a given neuronal network, or the necessity of quick adaptation to enhance the fitness of the animal. PMID:12644282

Lieshoff, Carsten; Bischof, Hans-Joachim

2003-03-18

176

Right thoracic curvature in the normal spine  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Trunk asymmetry and vertebral rotation, at times observed in the normal spine, resemble the characteristics of adolescent idiopathic scoliosis (AIS. Right thoracic curvature has also been reported in the normal spine. If it is determined that the features of right thoracic side curvature in the normal spine are the same as those observed in AIS, these findings might provide a basis for elucidating the etiology of this condition. For this reason, we investigated right thoracic curvature in the normal spine. Methods For normal spinal measurements, 1,200 patients who underwent a posteroanterior chest radiographs were evaluated. These consisted of 400 children (ages 4-9, 400 adolescents (ages 10-19 and 400 adults (ages 20-29, with each group comprised of both genders. The exclusion criteria were obvious chest and spinal diseases. As side curvature is minimal in normal spines and the range at which curvature is measured is difficult to ascertain, first the typical curvature range in scoliosis patients was determined and then the Cobb angle in normal spines was measured using the same range as the scoliosis curve, from T5 to T12. Right thoracic curvature was given a positive value. The curve pattern was organized in each collective three groups: neutral (from -1 degree to 1 degree, right (> +1 degree, and left ( Results In child group, Cobb angle in left was 120, in neutral was 125 and in right was 155. In adolescent group, Cobb angle in left was 70, in neutral was 114 and in right was 216. In adult group, Cobb angle in left was 46, in neutral was 102 and in right was 252. The curvature pattern shifts to the right side in the adolescent group (p Conclusions Based on standing chest radiographic measurements, a right thoracic curvature was observed in normal spines after adolescence.

Masuda Keigo

2011-01-01

177

Congenital block vertebrae in lumbar spine  

Directory of Open Access Journals (Sweden)

Full Text Available A 34-year-old female visited our rheumatology clinic with the complaint of non-inflammatory back pain that usually occurred on bending down and radiated to bilateral lower limbs. A diagnosis of compressive neuropathy was suspected and an initially performed digital X-ray of lumbar spine revealed a rare congenital anomaly termed as ‘Congenital block vertebrae’ in the lumbar spine (Fig 1.Block vertebrae, a congenital anomaly, occurs due to improper segmentation of vertebral column during fetal development. Improper segmentation leads to fusion of adjacent vertebrae through their inter-vertebral disc. The most common site of this deformity is cervical spine and the lumbar vertebral involvement is rare. The disco-vertebral articulation is always involved and depending on the degree of involvement, the presenting complaints could be either neurological due to the compression of nerve roots or scoliosis due to the vertebral deformity.

Ankur Nandan Varshney

2013-05-01

178

Preoperative Embolization of Cervical Spine Tumors  

International Nuclear Information System (INIS)

Purpose: To assess the technical success rate, complications, and effect on intraoperative blood loss of preoperative transarterial embolization of cervical spine tumors. Methods: A retrospective analysis was performed on 38 patients with tumors of the cervical spine; 69 vertebrae were affected. Polyvinyl alcohol particles, coils, gelfoam particles, either alone or in combination, were used for preoperative tumor embolization. After embolization a total of 57 corporectomies with titanium basket implantation were performed. Results: In 36 of 38 patients, complete (n= 27) or partial (n= 9) embolization was achieved. In 23 patients one vertebral artery was completely occluded by coil placement, and in one patient the ipsilateral internal and external carotid arteries were occluded in addition. No neurological complications could be directly related to the embolization, but two postoperative brain stem infarctions occurred. The mean intraoperative blood loss was 2.4 L. Conclusion: Transarterial embolization of cervical spine tumors is a safe and effective procedure to facilitate extensive surgery

1997-09-01

179

Visualizing the spine using anatomical knowledge  

Science.gov (United States)

In vivo anatomy is now routinely displayed as 2-D and 3-D images obtained from Computed X-ray Tomograpy (CT), Magnetic Resonance Imaging (MRI), and other diagnostic modalities. Most current medical visualization methods rely on pixel intensities to segment the data into tissues. However, structural features must be differentiated by a human operator, and geometric measurements of the anatomy are tedious and error prone to compute. This paper describes processing and imaging methods to aid the interpretation of CT studies of the spine. These procedures incorporate knowledge of the symmetry, shapes, and spatial relationships of vertebrae to locate the spinal cord and major components of vertebral bone from CT slices of the spine and automatically compute anatomical measurements. Results of these methods are shown as applied to the cervical (neck) and lumbar (lower back) regions of the spine.

Cornelius, Craig W.; Fellingham, Linda L.

1990-08-01

180

Image quality in conventional lumbar spine radiography  

International Nuclear Information System (INIS)

Conventional radiography contributes for the majority of examinations in radiology departments. Based on the European Commission Quality Criteria we evaluated the effects on image quality when applying the new post-processing tool Diamond View (Siemens AG Medical Solutions, Germany) to conventional lumbar spine radiographs. 100 digital image pairs in two directions in two planes of lumbar spine radiographs were prospectively evaluated by two radiologists. Statistical analysis was performed with a p-value < .05 considered as significant. Images were evaluated on basis of the modified imaging Quality Criteria by the Commission of the European Communities, rated on a five-point scale. Statistical analysis showed an overall tendency for improved image quality of Diamond View (DV) for all criteria. Significant differences could be found in most of the criteria. Additional phantom analyses supported the advantage of DV. In conclusion DV improves image quality in conventional lumbar spine radiographs.

2009-05-01

 
 
 
 
181

Airway management in cervical spine injury  

Science.gov (United States)

To minimize risk of spinal cord injury, airway management providers must understand the anatomic and functional relationship between the airway, cervical column, and spinal cord. Patients with known or suspected cervical spine injury may require emergent intubation for airway protection and ventilatory support or elective intubation for surgery with or without rigid neck stabilization (i.e., halo). To provide safe and efficient care in these patients, practitioners must identify high-risk patients, be comfortable with available methods of airway adjuncts, and know how airway maneuvers, neck stabilization, and positioning affect the cervical spine. This review discusses the risks and benefits of various airway management strategies as well as specific concerns that affect patients with known or suspected cervical spine injury.

Austin, Naola; Krishnamoorthy, Vijay; Dagal, Arman

2014-01-01

182

Functional oblique views of the lumbar spine  

International Nuclear Information System (INIS)

The first part of the paper deals with measurements of 152 radiographs. It was found that the conventional views of the lumbar spine in two planes can demonstrate only 49.1% of the articular joints. Oblique views in two planes increase the accuracy to 88.7%. In view of the relatively high accuracy of the oblique views, these were used as the basis for a new functional method for examining the intervertebral joints. For this examination, oblique views of the lumbar spine are taken in the lordotic and kyphotic positions. The position of the patient during the examination is described in detail. In the second part of the paper, the results of measurements of 80 functional examinations are evaluated. Average values for the mobility of individual elements of the lumbar spine have been derived. Finally, the practical value of the new technique is demonstrated. Its special place for subluxations and spondylolyses is stressed. (orig.)

1980-01-01

183

Genes Tied to Curvature of Spine in Kids  

Science.gov (United States)

... please enable JavaScript. Genes Tied to Curvature of Spine in Kids Finding might lead to ways to ... child's risk for severe scoliosis -- curvature of the spine. Children with these mutations have a quadrupled risk ...

184

Cervical spine fractures and dislocations in children  

International Nuclear Information System (INIS)

A retrospectivce analysis of pediatric admissions over 10 years revealed 29 patients with cervical spine injuries. Eleven patients were below 12 years of age, and 10 of these had injuries involving C1, C2 or the occipitoatlantal articulation. Eighteen patients were between 12 and 16 years of age with injuries distributed throughout the cervical spine similar to injuries in the adult population. Our results suggest that teenagers with suspected cervical injuries are best evaluated by an adult radiographic series including trauma oblique views. In younger patients, careful evaluation of occipitoatlantoaxial alignment and the prevertebral soft tissues is required for diagnosis and selection of additional imaging evaluation. (orig.)

1987-01-01

185

Stereotactic radiosurgery for brain and spine metastases.  

Science.gov (United States)

Metastases to the brain and spine are common and difficult to treat. Stereotactic radiosurgery (SRS) is a non-invasive treatment option for some individuals, and may obviate the need for open surgery and/or whole brain radiotherapy. Over the past decade there has been an increased number of patients undergoing SRS for the treatment of metastatic disease, and multiple published studies show favourable results in terms of local disease control. We review the available literature pertaining to the application of SRS for the treatment of brain and spine metastases, together with its limitations and outcomes. PMID:24373817

Bowden, Patrick J; See, Andrew W; Dally, Michael J; Bittar, Richard G

2014-05-01

186

Cervical spine fractures and dislocations in children  

Energy Technology Data Exchange (ETDEWEB)

A retrospectivce analysis of pediatric admissions over 10 years revealed 29 patients with cervical spine injuries. Eleven patients were below 12 years of age, and 10 of these had injuries involving C1, C2 or the occipitoatlantal articulation. Eighteen patients were between 12 and 16 years of age with injuries distributed throughout the cervical spine similar to injuries in the adult population. Our results suggest that teenagers with suspected cervical injuries are best evaluated by an adult radiographic series including trauma oblique views. In younger patients, careful evaluation of occipitoatlantoaxial alignment and the prevertebral soft tissues is required for diagnosis and selection of additional imaging evaluation.

Apple, J.S.; Kirks, D.R.; Merten, D.F.; Martinez, S.

1987-01-01

187

Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Dendritic spines are the major sites of excitatory synaptic input, and their morphological changes have been linked to learning and memory processes. Here, we report that growing microtubule plus ends decorated by the microtubule tip-tracking protein EB3 enter spines and can modulate spine morphology. We describe p140Cap/SNIP, a regulator of Src tyrosine kinase, as an EB3 interacting partner that is predominantly localized to spines and enriched in the postsynaptic density. Inhibition of micr...

Defilippi, Paola; Camera, Paola; Di Stefano, Paola

2009-01-01

188

A simple reproducible and time saving method of semi-automatic dendrite spine density estimation compared to manual spine counting  

DEFF Research Database (Denmark)

Estimation of spine number and spine density by manual counting under the assumption that all dendrite protrusions equal spines are often used in studies on neuroplasticity occurring during health, brain diseases, and different experimental paradigms. Manual spine counting is, however, time consuming and biased by inter-observer variation. We present accordingly a quick, reproducible and simple non-stereological semi-automatic spine density estimation method based on the irregularity of the dendrite surface. Using the freeware ImageJ program, microphotographs of Golgi impregnated hippocampal dendrites derived from a previously performed study on the impact of chronic restrained stress were binarized, skeletonized, and the skeleton endings assumed to represent spine positions were counted and the spine densities calculated. The results based on 754 dendrite fragments were compared to manual spine counting of the same dendrite fragments using the Bland-Altman method. The results from both methods were correlated (r=0.79, p

Orlowski, Dariusz; Bjarkam, C R

2012-01-01

189

A prospective study of spine fractures diagnosed by total spine computed tomography in high energy trauma patients  

International Nuclear Information System (INIS)

Since it is known to be impossible to identify spinal fractures in high-energy trauma patients the primary trauma evaluation, we have been performing total spine computed tomography (CT) in high-energy trauma cases. We investigated the spinal fractures that it was possible to detect by total spine CT in 179 cases and evaluated the usefulness of total spine CT prospectively. There were 54 (30.2%) spinal fractures among the 179 cases. Six (37.5%) of the 16 cervical spine fractures that were not detected on plain X-ray films were identified by total spine CT. Six (14.0%) of 43 thoracolumbar spine fractures were considered difficult to diagnose based on the clinical findings if total spine CT had not been performed. We therefore concluded that total spine CT is very useful and should be performed during the primary trauma evaluation in high-energy trauma cases. (author)

2011-01-01

190

49 CFR 572.85 - Lumbar spine flexure.  

Science.gov (United States)

...2010-10-01 2010-10-01 false Lumbar spine flexure. 572.85 Section 572...DEVICES 9-Month Old Child § 572.85 Lumbar spine flexure. (a) When subjected...with paragraph (b) of this section, the lumbar spine assembly shall flex by an...

2010-10-01

191

49 CFR 572.9 - Lumbar spine, abdomen, and pelvis.  

Science.gov (United States)

...2010-10-01 2010-10-01 false Lumbar spine, abdomen, and pelvis. 572.9 Section... 50th Percentile Male § 572.9 Lumbar spine, abdomen, and pelvis. (a) The lumbar spine, abdomen, and pelvis consist of the...

2010-10-01

192

49 CFR 572.19 - Lumbar spine, abdomen and pelvis.  

Science.gov (United States)

...2010-10-01 2010-10-01 false Lumbar spine, abdomen and pelvis. 572.19 Section... 3-Year-Old Child § 572.19 Lumbar spine, abdomen and pelvis. (a) The lumbar spine, abdomen, and pelvis consist of the...

2010-10-01

193

49 CFR 572.85 - Lumbar spine flexure.  

Science.gov (United States)

...2010-10-01 2010-10-01 false Lumbar spine flexure. 572.85 Section 572.85...9-Month Old Child § 572.85 Lumbar spine flexure. (a) When subjected to continuously...paragraph (b) of this section, the lumbar spine assembly shall flex by an amount that...

2010-10-01

194

Low-grade osteosarcoma of the spine: a case report  

Energy Technology Data Exchange (ETDEWEB)

Low-grade osteosarcoma is not typically found in the long bone and pelvis. Most primary osteosarcomas that arise in the spine are high-grade malignancies. A low-grade osteosarcoma arising in the spine has not been previously described. We report here the clinical, radiological, and histological findings of a case of low-grade osteosarcoma that arose in the spine.

Kim, Young Chul; Suh, Jin Suck; Kim, Myung In; Choo, Hye Jung; Huh, Yong Min [Yonsei University College of Medicine, Seoul (Korea, Republic of)

2007-06-15

195

Low-grade osteosarcoma of the spine: a case report  

International Nuclear Information System (INIS)

Low-grade osteosarcoma is not typically found in the long bone and pelvis. Most primary osteosarcomas that arise in the spine are high-grade malignancies. A low-grade osteosarcoma arising in the spine has not been previously described. We report here the clinical, radiological, and histological findings of a case of low-grade osteosarcoma that arose in the spine

2007-06-01

196

Super-Brownian motion: Lp-convergence of martingales through the pathwise spine decomposition  

CERN Document Server

Evans (1992) described the semi-group of a superprocess with quadratic branching mechanism under a martingale change of measure in terms of the semi-group of an immortal particle and the semigroup of the superprocess prior to the change of measure. This result, commonly referred to as the spine decomposition, alludes to a pathwise decomposition in which independent copies of the original process `immigrate' along the path of the immortal particle. For branching particle diffusions the analogue of this decomposition has already been demonstrated in the pathwise sense, see for example Hardy and Harris (2009). The purpose of this short note is to exemplify a new {\\it pathwise} spine decomposition for supercritical super-Brownian motion with general branching mechanism (cf. Kyprianou et al. (2010)) by studying $L^p$ convergence of naturally underlying additive martingales in the spirit of analogous arguments for branching particle diffusions due to Hardys and Harris (2009). Amongst other ingredients, the Dynkin-K...

Murillo-Salas, A E Kyprianou A

2011-01-01

197

Spine Stereotactic Body Radiotherapy Utilizing Cone-Beam CT Image-Guidance With a Robotic Couch: Intrafraction Motion Analysis Accounting for all Six Degrees of Freedom  

International Nuclear Information System (INIS)

Purpose: To evaluate the residual setup error and intrafraction motion following kilovoltage cone-beam CT (CBCT) image guidance, for immobilized spine stereotactic body radiotherapy (SBRT) patients, with positioning corrected for in all six degrees of freedom. Methods and Materials: Analysis is based on 42 consecutive patients (48 thoracic and/or lumbar metastases) treated with a total of 106 fractions and 307 image registrations. Following initial setup, a CBCT was acquired for patient alignment and a pretreatment CBCT taken to verify shifts and determine the residual setup error, followed by a midtreatment and posttreatment CBCT image. For 13 single-fraction SBRT patients, two midtreatment CBCT images were obtained. Initially, a 1.5-mm and 1° tolerance was used to reposition the patient following couch shifts which was subsequently reduced to 1 mm and 1° degree after the first 10 patients. Results: Small positioning errors after the initial CBCT setup were observed, with 90% occurring within 1 mm and 97% within 1°. In analyzing the impact of the time interval for verification imaging (10 ± 3 min) and subsequent image acquisitions (17 ± 4 min), the residual setup error was not significantly different (p > 0.05). A significant difference (p = 0.04) in the average three-dimensional intrafraction positional deviations favoring a more strict tolerance in translation (1 mm vs. 1.5 mm) was observed. The absolute intrafraction motion averaged over all patients and all directions along x, y, and z axis (± SD) were 0.7 ± 0.5 mm and 0.5 ± 0.4 mm for the 1.5 mm and 1 mm tolerance, respectively. Based on a 1-mm and 1° correction threshold, the target was localized to within 1.2 mm and 0.9° with 95% confidence. Conclusion: Near-rigid body immobilization, intrafraction CBCT imaging approximately every 15–20 min, and strict repositioning thresholds in six degrees of freedom yields minimal intrafraction motion allowing for safe spine SBRT delivery.

2012-03-01

198

DRAR-CPI: a server for identifying drug repositioning potential and adverse drug reactions via the chemical–protein interactome  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Identifying new indications for existing drugs (drug repositioning) is an efficient way of maximizing their potential. Adverse drug reaction (ADR) is one of the leading causes of death among hospitalized patients. As both new indications and ADRs are caused by unexpected chemical–protein interactions on off-targets, it is reasonable to predict these interactions by mining the chemical–protein interactome (CPI). Making such predictions has recently been facilitated by a web server named DR...

Luo, Heng; Chen, Jian; Shi, Leming; Mikailov, Mike; Zhu, Huang; Wang, Kejian; He, Lin; Yang, Lun

2011-01-01

199

Cortical dendritic spine heads are not electrically isolated by the spine neck from membrane potential signals in parent dendrites.  

Science.gov (United States)

The evidence for an important hypothesis that cortical spine morphology might participate in modifying synaptic efficacy that underlies plasticity and possibly learning and memory mechanisms is inconclusive. Both theory and experiments suggest that the transfer of excitatory postsynaptic potential signals from spines to parent dendrites depends on the spine neck morphology and resistance. Furthermore, modeling of signal transfer in the opposite direction predicts that synapses on spine heads are not electrically isolated from voltages in the parent dendrite. In sharp contrast to this theoretical prediction, one of a very few measurements of electrical signals from spines reported that slow hyperpolarizing membrane potential changes are attenuated considerably by the spine neck as they spread from dendrites to synapses on spine heads. This result challenges our understanding of the electrical behavior of spines at a fundamental level. To re-examine the specific question of the transfer of dendritic signals to synapses of spines, we took advantage of a high-sensitivity Vm-imaging technique and carried out optical measurements of electrical signals from 4 groups of spines with different neck length and simultaneously from parent dendrites. The results show that spine neck does not filter membrane potential signals as they spread from the dendrites into the spine heads. PMID:23054810

Popovic, Marko A; Gao, Xin; Carnevale, Nicholas T; Zecevic, Dejan

2014-02-01

200

Posterior arch defects of the cervical spine  

International Nuclear Information System (INIS)

Spondylolysis and absence of the pedicle are congenital anomalies of the posterior cervical spine. Their roentgenographic changes may be confused with other more serious entities which may necessitate either emergent therapy or require extensive diagnostic testing and treatment. Four cases are present and the literature is reviewed. A hypothesis for the embryologic etiology of these entities is proposed. (orig.)

1982-01-01

 
 
 
 
201

Striatal spine plasticity in Parkinson's Disease  

Directory of Open Access Journals (Sweden)

Full Text Available Striatal dopamine (DA denervation results in a significant loss of dendritic spines on medium spiny projection neurons in Parkinson’s disease (PD. In 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP-treated parkinsonian monkeys, spines contacted either by cortical or thalamic glutamatergic terminals are severely affected on both direct and indirect striatofugal neurons. In rodents, indirect pathway neurons appear to be more sensitive, at least in early stages of acute dopamine denervation. The remaining corticostriatal and thalamostriatal axo-spinous synapses undergo complex ultrastructural remodeling consistent with increased synaptic activity in the DA-denervated primate striatum, which may explain the pathophysiological overactivity of the corticostriatal system reported in various animal models of parkinsonism. The calcium-mediated regulation of the transcription factor myocyte enhancer factor 2 (MEF2 was recognized as a possible underlying mechanism for striatal spine plasticity. Future studies to determine how alterations in striatal spine plasticity contribute to the symptomatology of parkinsonism are warranted.

RosaMVillalba

2010-12-01

202

Posterior arch defects of the cervical spine  

Energy Technology Data Exchange (ETDEWEB)

Spondylolysis and absence of the pedicle are congenital anomalies of the posterior cervical spine. Their roentgenographic changes may be confused with other more serious entities which may necessitate either emergent therapy or require extensive diagnostic testing and treatment. Four cases are present and the literature is reviewed. A hypothesis for the embryologic etiology of these entities is proposed.

Schwartz, A.M.; Wechsler, R.J.; Landy, M.D.; Wetzner, S.M.; Goldstein, S.A.

1982-05-01

203

X-Ray parameters of lumbar spine  

Directory of Open Access Journals (Sweden)

Full Text Available Knowledge of anatomic spinal structures, especially its relation-ship to the functions performed, is necessary to form a correct diagnosis. The anatomical structure of the vertebrae varies de-pending on the level of the spinal segment. Normal anatomical parameters, derived from bone structures of the spine, are roughly determined by X-ray method.This paper presents the results of the survey radiography of the lumbar spine in a straight line and lateral projections in 30 individ-uals without pathology spine, aged 21-60 years with frequently observed lumbar spinal stenosis stenosis. Applying X-ray method there were studied shape, height, and the contours of the vertebral bodies and intervertebral disc in the front (interpedicular and sagittal planes; there were measured dimensions of the lumbar canal and foramen holes in the same planes. Using X-ray method can fully identify the bone parameters of vertebral column. How-ever, the informativity of the method depends on knowledge of radiologist about topographic anatomical features of spine.

Otabek Ablyazov

2012-05-01

204

Anatomy of large animal spines and its comparison to the human spine: a systematic review  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Animal models have been commonly used for in vivo and in vitro spinal research. However, the extent to which animal models resemble the human spine has not been well known. We conducted a systematic review to compare the morphometric features of vertebrae between human and animal species, so as to give some suggestions on how to choose an appropriate animal model in spine research. A literature search of all English language peer-reviewed publications was conducted using PubMed, OVID, Springe...

Sheng, Sun-ren; Wang, Xiang-yang; Xu, Hua-zi; Zhu, Guo-qing; Zhou, Yi-fei

2010-01-01

205

Assessment of berberine as a multi-target antimicrobial: a multi-omics study for drug discovery and repositioning.  

Science.gov (United States)

Postgenomics drug development is undergoing major transformation in the age of multi-omics studies and drug repositioning. Rather than applications solely in personalized medicine, omics science thus additionally offers a better understanding of a broader range of drug targets and drug repositioning. Berberine is an isoquinoline alkaloid found in many medicinal plants. We report here a whole genome microarray study in tandem with proteomics techniques for mining the plethora of targets that are putatively involved in the antimicrobial activity of berberine against Escherichia coli. We found DNA replication/repair and transcription to be triggered by berberine, indicating that nucleic acids, in general, are among its targets. Our combined transcriptomics and proteomics multi-omics findings underscore that, in the presence of berberine, cell wall or cell membrane transport and motility-related functions are also specifically regulated. We further report a general decline in metabolism, as seen by repression of genes in carbohydrate and amino acid metabolism, energy production, and conversion. An involvement of multidrug efflux pumps, as well as reduced membrane permeability for developing resistance against berberine in E. coli was noted. Collectively, these findings offer original and significant leads for omics-guided drug discovery and future repositioning approaches in the postgenomics era, using berberine as a multi-omics case study. PMID:24237354

Karaosmanoglu, Kubra; Sayar, Nihat Alpagu; Kurnaz, Isil Aksan; Akbulut, Berna Sariyar

2014-01-01

206

DRUGSURV: a resource for repositioning of approved and experimental drugs in oncology based on patient survival information.  

Science.gov (United States)

The use of existing drugs for new therapeutic applications, commonly referred to as drug repositioning, is a way for fast and cost-efficient drug discovery. Drug repositioning in oncology is commonly initiated by in vitro experimental evidence that a drug exhibits anticancer cytotoxicity. Any independent verification that the observed effects in vitro may be valid in a clinical setting, and that the drug could potentially affect patient survival in vivo is of paramount importance. Despite considerable recent efforts in computational drug repositioning, none of the studies have considered patient survival information in modelling the potential of existing/new drugs in the management of cancer. Therefore, we have developed DRUGSURV; this is the first computational tool to estimate the potential effects of a drug using patient survival information derived from clinical cancer expression data sets. DRUGSURV provides statistical evidence that a drug can affect survival outcome in particular clinical conditions to justify further investigation of the drug anticancer potential and to guide clinical trial design. DRUGSURV covers both approved drugs (?1700) as well as experimental drugs (?5000) and is freely available at http://www.bioprofiling.de/drugsurv. PMID:24503543

Amelio, I; Gostev, M; Knight, R A; Willis, A E; Melino, G; Antonov, A V

2014-01-01

207

Can sodium/hydrogen exchange inhibitors be repositioned for treating attention deficit hyperactivity disorder? An in silico approach.  

Science.gov (United States)

Medications for attention deficit hyperactivity disorder (ADHD) are only partially effective. Ideally, new treatment targets would derive from a known pathophysiology. Such data are not available for ADHD. We combine evidence for new etiologic pathways with bioinformatics data to assess the possibility that existing drugs might be repositioning for treating ADHD. We use this approach to determine if prior data implicating the sodium/hydrogen exchanger 9 gene (SLC9A9) in ADHD implicate sodium/hydrogen exchange (NHE) inhibitors as potential treatments. We assessed the potential for repositioning by assessing the similarity of drug-protein binding profiles between NHE inhibitors and drugs known to treat ADHD using the Drug Repositioning and Adverse Reaction via Chemical-Protein Interactome server. NHE9 shows a high degree of amino acid similarity between NHE inhibitor sensitive NHEs in the region of the NHE inhibitor recognition site defined for NHE1. We found high correlations in drug-protein binding profiles among most ADHD drugs. The drug-protein binding profiles of some NHE inhibitors were highly correlated with ADHD drugs whereas the profiles for a control set of nonsteroidal anti-inflammatory drugs (NSAIDs) were not. Further experimental work should evaluate if NHE inhibitors are suitable for treating ADHD. PMID:24132903

Faraone, Stephen V; Zhang-James, Yanli

2013-10-01

208

Lower leg neuromuscular changes following fibular reposition taping in individuals with chronic ankle instability.  

Science.gov (United States)

Soleus and peroneus longus arthrogenic muscle inhibition has been reported in patients with chronic ankle instability. Fibular reposition taping (FRT) has been shown to improve outcomes however, the influence of FRT on neuromuscular function is unknown. The purpose was to determine the effects of FRT on soleus and peroneus longus h-reflex amplitude in patients with chronic ankle instability. This was a randomized, single blind, sham-controlled crossover laboratory experiment. Twelve young adults with chronic ankle instability (age: 21.5 ± 1.6, height: 173.8 ± 10.4, mass: 72.8 ± 16.3) participated in two testing sessions. We measured peak h-reflex and M-wave of the soleus and peroneus longus and v-wave of the soleus only. Measurements were recorded before and after the application of FRT or a sham tape intervention. Sessions were separated by a week and counterbalanced, h-reflex and v-wave were normalized to M-wave at each time point. Significant increase in h/M ratio was observed in the soleus following FRT compared to baseline, but not after the sham intervention. No difference in peroneus longus h/M ratio or soleus v/M ratio was observed in any session. FRT may be an effective modality for increasing soleus h-reflex for patients with chronic ankle instability. PMID:23302515

Chou, Esther; Kim, Kyung-Min; Baker, Andrew G; Hertel, Jay; Hart, Joseph M

2013-08-01

209

Evaluation of temporomandibular joint disc-repositioning surgery with Mitek mini anchors  

Science.gov (United States)

Purpose: The aim of this study is to evaluate outcome of Mitek mini anchors (DePuy Mitek, Raynham, MA) in TMJ discopexy and assess patient satisfaction based on MRI findings. Patients and Methods: 7 patients suffered from significant pain and dysfunction diagnosed on MRI findings as anterior disc displacement without reduction selected for this study. Anchor stability, assessment of positional changes and roofing were evaluated by postop MRI and OPTGs. Satisfaction was assessed with VAS. Preop and postop maximum interincisal opening measurements were compared. Results: There was significant difference between preop and posto P values of MIO and VAS. All 7 patients noted complete absence of pain at the postop 1-year follow-up. Only 1 patient had postop clicking but showed remarkable improvement of jaw functions (MIO). The articular disk was observed at its normal position in 6 patients except one patient whom MRI confirmed postop partial roofing. OPTGs reveal neither radiologic changes around the mini anchors in the condylar head nor any positional shifts. Conclusion: Disc repositioning with Mitek mini anchors represent improvement in post-op VAS scores and clinical findings (MIO) based on comparison preop and postop MRI scans and panoramic films. However, our study group consists of limited number of patients, further studies with more number of cases are required to evaluate the outcomes

Gocmen, Gokhan; Varol, Altan; Karatas, Berfin; Basa, Selcuk

2013-01-01

210

Tubular foreign body or stent: safe retrieval or repositioning using the coaxial snare technique  

International Nuclear Information System (INIS)

To evaluate the utility and advantages of the coaxial snare technique in the retrieval of tubular foreign bodies. Using the coaxial snare technique, we attempted to retrieve tubular foreign bodies present in seven patients. The bodies were either stents which were malpositioned or had migrated from their correct position in the vascular system (n=2), a fragmented venous introducer sheath (n=1), fragmented drainage catheters in the biliary tree (n=2), or fractured external drainage catheters in the urinary tract (n=2). After passing a guidewire and/or a dilator through the lumina of these foreign bodies, we introduced a loop snare over the guidewire or dilator, thus capturing and retrieving them. In all cases, it was possible to retrieve or reposition the various items, using a minimum-sized introducer sheath or a tract. No folding was involved. In no case were surgical procedures required, and no complications were encountered. The coaxial snare technique, an application of the loop snare technique, is a useful and safe method for the retrieval of tubular foreign bodies, and one which involves minimal injury to the patient

2002-01-01

211

The Effectiveness of a Modified Type of the Mandibular Repositioning Device on the Elimination of Snoring  

Directory of Open Access Journals (Sweden)

Full Text Available Statement of Problem: Snoring is the most common sleep disorder which in itself may only be viewed as an obnoxious disturbance in human society; however it must be considered a potential indicator of significant medical problems such as: hypertension,obstructive sleep apnea, cerebrovascular infarction and ischemic heart disease.Purpose: The purpose of this study was to evaluate the effectiveness of a modified type of Mandibular Repositioning Device (MRD splint on the treatment of snoring.Materials and Methods: This before and after interventional study was carried out on 15 patients (4 females and 11 males who suffered from snoring. All subjects had no upper airway obstruction. Maxillary and mandibular splints were made by clear heatcuredacrylic resin. A special screw connected to the anterior portion of the maxillary splint and an orthodontic wire No 1 positioned on the lower splint. The devices were tried in the mouth and relined with a softliner. This appliance was designed to protrude the mandible by use of a screw system. Snoring grades were detemined before, and 3weeks after treatment with the MRD. Data were analyzed by the Wilcoxon test.Results: A significant difference was observed between the snoring severity, before and after using the splints (P = 0.001.Conclusion: The present study showed this modified type of splint can be effective in decreasing or eliminating snoring. The effectiveness of the splint in the treatment of snoring could be related to its role of widening the upper airway.

B. Ebadian

2005-09-01

212

Whole-body MRI using a sliding table and repositioning surface coil approach  

Energy Technology Data Exchange (ETDEWEB)

To introduce and assess a new way of performing whole-body magnetic resonance imaging (MRI) using a non-integrated surface coil approach as available on most clinical MRI systems worldwide. Ten consecutive asymptomatic subjects prospectively underwent whole-body MRI for health screening. Whole-body MRI included T1-, T2- and diffusion-weighted sequences, and was performed using a non-integrated surface coil to image four different stations without patient repositioning. The four separately acquired stations were merged, creating seamless coronal whole-body T1-, T2- and diffusion-weighted images. Anatomical alignment, image quality at the boundaries of adjacent stations, and overall image quality of all stations were qualitatively assessed. The average time ({+-}SD) taken to change the surface coil from one station to the next station was 53.8 ({+-}7.1) s. The average total extra examination time {+-} SD was 2 min 41.4 s ({+-}15.3 s). Anatomical alignment, image quality at the boundaries of adjacent stations, and overall image quality of all stations of T1-, T2- and diffusion-weighted whole-body MRI were overall graded as ''good'' to ''excellent''. This study shows that a time-efficient and high-quality whole-body MRI examination can easily be performed by using a non-integrated sliding surface coil approach. (orig.)

Takahara, Taro; Kwee, Thomas; Luijten, Peter [University Medical Centre Utrecht, Department of Radiology, Heidelberglaan 100, P.O. Box 85500, Utrecht (Netherlands); Kibune, Satoshi [Koga Hospital 21, Department of Radiology, Kurume, Fukuoka (Japan); Ochiai, Reiji [Fukuoka Hospital, Department of Radiology, Fukuoka, Fukuoka (Japan); Sakamoto, Tetsuro [Philips Healthcare Japan, Shinagawa (Japan); Niwa, Tetsu [University Medical Centre Utrecht, Department of Radiology, Heidelberglaan 100, P.O. Box 85500, Utrecht (Netherlands); Kanagawa Children' s Medical Center, Department of Radiology, Yokohama (Japan); Van Cauteren, Marc [Philips Healthcare, Asia Pacific, Shinagawa (Japan)

2010-06-15

213

From periphery to the centre: Towards repositioning churches for a meaningful contribution to public health care  

Directory of Open Access Journals (Sweden)

Full Text Available The role of communities in health care has gained prominence in the last few years. Churches as community structures have been identified as instrumental in health-care delivery. Whilst it is widely acknowledged that churches provide important health services, particularly in countries where there are poorly-developed health sectors, the role of churches in health care is poorly understood and often overlooked. This article discusses some causes of this lacuna and makes suggestions for repositioning churches for a meaningful contribution to health care. Firstly, the article provides a context by reviewing literature on the church and health care. Secondly, it clarifies the nature of interventions and the competencies of churches. Thirdly, it discusses the operational meaning of church and churches for assessing health-care contributions. Fourthly, it explores the health-care models that are discerned in church and health-care literature. Fifthly, it discusses the contribution of churches within a multidisciplinary health team. Sixthly, it proposes an appropriate motivation that should drive churches to be involved in health care and the ecclesiological design that underpins such health care interventions.

Vhumani Magezi

2012-12-01

214

From periphery to the centre: towards repositioning churches for a meaningful contribution to public health care  

Scientific Electronic Library Online (English)

Full Text Available SciELO South Africa | Language: English Abstract in english The role of communities in health care has gained prominence in the last few years. Churches as community structures have been identified as instrumental in health-care delivery. Whilst it is widely acknowledged that churches provide important health services, particularly in countries where there a [...] re poorly-developed health sectors, the role of churches in health care is poorly understood and often overlooked. This article discusses some causes of this lacuna and makes suggestions for repositioning churches for a meaningful contribution to health care. Firstly, the article provides a context by reviewing literature on the church and health care. Secondly, it clarifies the nature of interventions and the competencies of churches. Thirdly, it discusses the operational meaning of church and churches for assessing health-care contributions. Fourthly, it explores the health-care models that are discerned in church and health-care literature. Fifthly, it discusses the contribution of churches within a multidisciplinary health team. Sixthly, it proposes an appropriate motivation that should drive churches to be involved in health care and the ecclesiological design that underpins such health care interventions.

Magezi, Vhumani.

215

Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors  

Energy Technology Data Exchange (ETDEWEB)

The screening of bioactive compound libraries can be an effective approach for repositioning FDA-approved drugs or discovering new pharmacophores. Hookworms are blood-feeding, intestinal nematode parasites that infect up to 600 million people worldwide. Vaccination with recombinant Ancylostoma ceylanicum macrophage migration inhibitory factor (rAceMIF) provided partial protection from disease, thus establishing a 'proof-of-concept' for targeting AceMIF to prevent or treat infection. A high-throughput screen (HTS) against rAceMIF identified six AceMIF-specific inhibitors. A nonsteroidal anti-inflammatory drug (NSAID), sodium meclofenamate, could be tested in an animal model to assess the therapeutic efficacy in treating hookworm disease. Furosemide, an FDA-approved diuretic, exhibited submicromolar inhibition of rAceMIF tautomerase activity. Structure-activity relationships of a pharmacophore based on furosemide included one analog that binds similarly to the active site, yet does not inhibit the Na-K-Cl symporter (NKCC1) responsible for diuretic activity.

Y Cho; J Vermeire; J Merkel; L Leng; X Du; R Bucala; M Cappello; E Lolis

2011-12-31

216

Variables Affecting Canalith Repositioning Maneuver (CRM Trend for Treating Patients with Benign Paroxysmal Positional Vertigo (BPPV  

Directory of Open Access Journals (Sweden)

Full Text Available Background: The purpose of this study was to identify variables affecting outcome in patients with benign paroxysmal positional vertigo (BPPV treated with canalith repositioning maneuver (CRM. Methods: This interventional study was conducted on 58 patients (14 males, 44 females, mean age 48.12+13.22 referred to the Vertigo Rehabilitation Clinic of the Rehabilitation School of Tehran University of Medical Sciences from 2002 to 2004. All patients were treated with CRM. According to the treatment efficacy the patients were allocated in three groups: completely treated, partially treated, and not treated. The effect of factors including age, sex, etiology, duration of BPPV, unilateral or bilateral disease, number of maneuvers, and number of sessions on outcome in patients was evaluated. Results: Forty-nine patients (84.5% were completely cured. Age, sex, etiology, and duration did not significantly affect the treatment outcome. Unilateral BPPV can be treated significantly better than bilateral BPPV. Forty-seven patients who were completely treated needed 1 session and thirty-seven of them required 2 maneuvers. Conclusion: CRM is significantly effective for BPPV treatment. Treating unilateral BPPV is expected to be easier. As most of the patients will be cured by 1 or 2 maneuvers or in 1 session, patients who required more sessions or more maneuvers may not be completely treated.

E. Entezari

2006-07-01

217

Pharyngeal perforation: a late complication of cervical spine surgery.  

Science.gov (United States)

Anterior cervical spine fusion and stabilization is a well-recognized procedure for a number of cervical spine disorders. Unfortunately, the complex anatomy of the cervical spine means that these procedures are not without complications. Pharyngo-oesophageal perforation is a rare but potentially life-threatening complication of cervical spine surgery and may present intra-operatively, in the immediate post-operative period or many years later. We present the case of a gentleman with ankylosing spondylitis who presented with a pharyngeal perforation and fistula five years after cervical spine surgery. PMID:16354347

Woolley, S L; Smith, D R K

2005-11-01

218

Effects of N-cadherin disruption on spine morphological dynamics  

Directory of Open Access Journals (Sweden)

Full Text Available Structural changes at synapses are thought to be a key mechanism for the encoding of memories in the brain. Recent studies have shown that changes in the dynamic behavior of dendritic spines accompany bidirectional changes in synaptic plasticity, and that the disruption of structural constraints at synapses may play a mechanistic role in spine plasticity. While the prolonged disruption of N-cadherin, a key synaptic adhesion molecule, has been shown to alter spine morphology, little is known about the short-term regulation of spine morphological dynamics by N-cadherin. With time-lapse, confocal imaging in cultured hippocampal neurons, we examined the progression of structural changes in spines following an acute treatment with AHAVD, a peptide known to interfere with the function of N-cadherin. We characterized fast and slow timescale spine dynamics (minutes and hours, respectively in the same population of spines. We show that N-cadherin disruption leads to enhanced spine motility and reduced length, followed by spine loss. The structural effects are accompanied by a loss of functional connectivity. Further, we demonstrate that early structural changes induced by AHAVD treatment, namely enhanced motility and reduced length, are indicators for later spine fate, i.e., spines with the former changes are more likely to be subsequently lost. Our results thus reveal the short-term regulation of synaptic structure by N-cadherin and suggest that some forms of morphological dynamics may be potential readouts for subsequent, stimulus-induced rewiring in neuronal networks.

ShreeshPMysore

2007-12-01

219

Does applying the Canadian Cervical Spine rule reduce cervical spine radiography rates in alert patients with blunt trauma to the neck? A retrospective analysis  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background A cautious outlook towards neck injuries has been the norm to avoid missing cervical spine injuries. Consequently there has been an increased use of cervical spine radiography. The Canadian Cervical Spine rule was proposed to reduce unnecessary use of cervical spine radiography in alert and stable patients. Our aim was to see whether applying the Canadian Cervical Spine rule reduced the need for cervical spine radiography without missing significant cervical spine injuries. Methods This was a retrospective study conducted in 2 hospitals. 114 alert and stable patients who had cervical spine radiographs for suspected neck injuries were included in the study. Data on patient demographics, high risk & low risk factors as per the Canadian Cervical Spine rule and cervical spine radiography results were collected and analysed. Results 28 patients were included in the high risk category according to the Canadian Cervical Spine rule. 86 patients fell into the low risk category. If the Canadian Cervical Spine rule was applied, there would have been a significant reduction in cervical spine radiographs as 86/114 patients (75.4% would not have needed cervical spine radiograph. 2/114 patients who had significant cervical spine injuries would have been identified when the Canadian Cervical Spine rule was applied. Conclusion Applying the Canadian Cervical Spine rule for neck injuries in alert and stable patients would have reduced the use of cervical spine radiographs without missing out significant cervical spine injuries. This relates to reduction in radiation exposure to patients and health care costs.

Yesupalan Rajam

2008-06-01

220

Remote Sensing  

CERN Multimedia

Remote Sensing provides information on how remote sensing relates to the natural resources inventory, management, and monitoring, as well as environmental concerns. It explains the role of this new technology in current global challenges. "Remote Sensing" will discuss remotely sensed data application payloads and platforms, along with the methodologies involving image processing techniques as applied to remotely sensed data. This title provides information on image classification techniques and image registration, data integration, and data fusion techniques. How this technology applies to natural resources and environmental concerns will also be discussed.

Khorram, Siamak; Koch, Frank H; van der Wiele, Cynthia F

2012-01-01

 
 
 
 
221

Biomechanics of the thoracic spine: development of a method to measure the influence of the rib cage on thoracic spine movement  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Little is known about the biomechanics of the thoracic spine. Biomechanical in-vitro-experiments are usually conducted with isolated thoracic spine specimens. The thorax performs a stabilizing and thereby limiting effect on thoracic spine flexibility.

2013-01-01

222

MRI of the spine in endemic fluorosis  

International Nuclear Information System (INIS)

Objective: To evaluate role of MRI in the diagnosis of the spinal lesions in endemic fluorosis. Methods: MRI of the spine in 81 patients with endemic fluorosis, including the cervical spine in 57 patients, thoracic spine in 10, and lumbar spine in 14, were analyzed and compared with X-ray plain films. Results: Fat-containing marrow in the vertebral bodies with endemic fluorosis was decreased and unevenly distributed. Signal intensity of the vertebral bodies was homogeneously or inhomogeneously decreased on T1- and T2- weighted images. The mean values of signal intensity of the cervical vertebral bodies from 3rd to 7th were lower in 32 patients with fluorosis than those in 100 patients of the control group on T1-weighted image (P1-weighted images, the signal intensity similar to yellow bone marrow within OPLL in 63 patients and within OYL in 36 patients was observed in 32 patients (50%) and in 31 patients (86%), respectively. Of the 81 patients, herniation of the intervertebral disk was found in 68 patients (84%), degeneration of the intervertebral disk was observed in 57 patients (70%), and spinal canal narrowing was found in 75 patients (93%), in which compression of the spinal cord was showed in 63 patients (78%) and pathologic changes within the cord were noted in 28 patients (35%). In 57 patients with fluorosis, MR showed compression of the cervical spinal cord in 48 patients (84.21%), the anterioposterior diameter of the cervical spinal canal on X-ray plain film was either 9 mm or less at any level of the vertebra (indicating the compression of the cervical spinal cord) in 41(71.92%) patients (P=0.115). In 57 patients with fluorosis and 100 patients of control group, intervertebral herniation was observed in 51 patients (89.47%) and 62 patients (62%), respectively (P<0.001), and intervertebral degeneration was noted in 37 patients (64.91%) and 37 patients (37%), respectively (P=0.001). Conclusion: The spine of endemic fluorosis with MR examination may interpret homogeneous or inhomogeneous low signal from the increasing activity of osteoblasts, content and distribution of the calcium fluoride and fat-containing bone marrow within the vertebral body. MR is superior to X-ray plain film in showing the compression and pathologic changes of the spine cord, intervertebral herniation, and intervertebral degeneration. (authors)

2004-10-01

223

Computational repositioning and preclinical validation of pentamidine for renal cell cancer.  

Science.gov (United States)

Although early stages of clear cell renal cell carcinoma (ccRCC) are curable, survival outcome for metastatic ccRCC remains poor. We previously established a highly accurate signature of differentially expressed genes that distinguish ccRCC from normal kidney. The purpose of this study was to apply a new individualized bioinformatics analysis (IBA) strategy to these transcriptome data in conjunction with Gene Set Enrichment Analysis of the Connectivity Map (C-MAP) database to identify and reposition FDA-approved drugs for anticancer therapy. Here, we demonstrate that one of the drugs predicted to revert the RCC gene signature toward normal kidney, pentamidine, is effective against RCC cells in culture and in a RCC xenograft model. ccRCC-specific gene expression signatures of individual patients were used to query the C-MAP software. Eight drugs with negative correlation and P-value RCC in vitro and in vivo. Our data demonstrate consistency across most patients with ccRCC for the set of high-scoring drugs. Most of the selected high-scoring drugs potently induce apoptosis in RCC cells. Several drugs also demonstrate selectivity for Von Hippel-Lindau negative RCC cells. Most importantly, at least one of these drugs, pentamidine, slows tumor growth in the 786-O human ccRCC xenograft mouse model. Our findings suggest that pentamidine might be a new therapeutic agent to be combined with current standard-of-care regimens for patients with metastatic ccRCC and support our notion that IBA combined with C-MAP analysis enables repurposing of FDA-approved drugs for potential anti-RCC therapy. Mol Cancer Ther; 13(7); 1929-41. ©2014 AACR. PMID:24785412

Zerbini, Luiz Fernando; Bhasin, Manoj K; de Vasconcellos, Jaira F; Paccez, Juliano D; Gu, Xuesong; Kung, Andrew L; Libermann, Towia A

2014-07-01

224

Construction of drug network based on side effects and its application for drug repositioning.  

Science.gov (United States)

Drugs with similar side-effect profiles may share similar therapeutic properties through related mechanisms of action. In this study, a drug-drug network was constructed based on the similarities between their clinical side effects. The indications of a drug may be inferred by the enriched FDA-approved functions of its neighbouring drugs in the network. We systematically screened new indications for 1234 drugs with more than 2 network neighbours, 36.87% of the drugs achieved a performance score of Normalized Discounted Cumulative Gain in the top 5 positions (NDCG@5) ? 0.7, which means most of the known FDA-approved indications were well predicted at the top 5 positions. In particular, drugs for diabetes, obesity, laxatives and antimycobacterials had extremely high performance with more than 80% of them achieving NDCG@5 ? 0.7. Additionally, by manually checking the predicted 1858 drug-indication pairs with Expression Analysis Systematic Explorer (EASE) score ? 10(-5) (EASE score is a rigorously modified Fisher exact test p value), we found that 80.73% of such pairs could be verified by preclinical/clinical studies or scientific literature. Furthermore, our method could be extended to predict drugs not covered in the network. We took 98 external drugs not covered in the network as the test sample set. Based on our similarity criteria using side effects, we identified 41 drugs with significant similarities to other drugs in the network. Among them, 36.59% of the drugs achieved NDCG@5 ? 0.7. In all of the 106 drug-indication pairs with an EASE score ? 0.05, 50.94% of them are supported by FDA approval or preclinical/clinical studies. In summary, our method which is based on the indications enriched by network neighbors may provide new clues for drug repositioning using side effects. PMID:24505324

Ye, Hao; Liu, Qi; Wei, Jia

2014-01-01

225

Upright positional MRI of the lumbar spine  

International Nuclear Information System (INIS)

Supine magnetic resonance imaging (MRI) is routinely used in the assessment of low back pain and radiculopathy. However, imaging findings often correlate poorly with clinical findings. This is partly related to the positional dependence of spinal stenosis, which reflects dynamic changes in soft-tissue structures (ligaments, disc, dural sac, epidural fat, and nerve roots). Upright MRI in the flexed, extended, rotated, standing, and bending positions, allows patients to reproduce the positions that bring about their symptoms and may uncover MRI findings that were not visible with routine supine imaging. Assessment of the degree of spinal stability in the degenerate and postoperative lumbar spine is also possible. The aim of this review was to present the current literature concerning both the normal and symptomatic spine as imaged using upright MRI and to illustrate the above findings using clinical examples

2008-09-01

226

Electroradiography of the spine and pelvic bones  

International Nuclear Information System (INIS)

During examination of the spine an optimal regimen and exposition conditions of electroradiologic process have been studied with regard to the resolving power and X-ray doses. Experiments with aqueous-osteal phantoms and on 60 patients have shown that it is advisable to use screens while taking X-ray films, in order to preserve high quality of electroradiography of the massive spinal sections (thoracic and lumbar) as well as the pelvic bones. Taking into consideration higher X-ray doses in electroradiography compared to those in X-ray films, the indications for this method employment in examination of the spine should be more strict. It is advisable to apply electroradiography to patients with malignant neoplasms

1982-01-01

227

Stereotactic body radiotherapy for solitary spine metastasis  

International Nuclear Information System (INIS)

A clear consensus has not been established regarding the best treatment for solitary bone metastasis. Here, we reviewed the medical records of patients with a controlled primary malignancy who had only solitary spine metastasis without metastasis to the extraspinal bone or viscera and underwent treatment between April 2007 and December 2012 with stereotactic body radiosurgery using CyberKnife, with a total dose of 24 Gy in three to four fractions. During that time, there were only four cases. This was effective in each case, and all the four patients had no local failure and remained alive at a median follow-up of 68 months (range, 64 to 80 months). Although our experience is limited, this study suggests that stereotactic body radiotherapy could be a feasible, safe, effective, and noninvasive alternative treatment for solitary spine metastasis in patients who are medically inoperable or unsuitable for surgery.

2013-12-01

228

Stereotactic body radiotherapy for solitary spine metastasis  

Energy Technology Data Exchange (ETDEWEB)

A clear consensus has not been established regarding the best treatment for solitary bone metastasis. Here, we reviewed the medical records of patients with a controlled primary malignancy who had only solitary spine metastasis without metastasis to the extraspinal bone or viscera and underwent treatment between April 2007 and December 2012 with stereotactic body radiosurgery using CyberKnife, with a total dose of 24 Gy in three to four fractions. During that time, there were only four cases. This was effective in each case, and all the four patients had no local failure and remained alive at a median follow-up of 68 months (range, 64 to 80 months). Although our experience is limited, this study suggests that stereotactic body radiotherapy could be a feasible, safe, effective, and noninvasive alternative treatment for solitary spine metastasis in patients who are medically inoperable or unsuitable for surgery.

Lee, Sun Young [Dept. of Radiation Oncology, Sun Medical Center, Daejeon (Korea, Republic of); Chun, Mison [Dept. of Radiation Oncology, Ajou University School of Medicine, Suwon (Korea, Republic of); Lee, Mi Jo [Dept. of Radiation Oncology, Eulji Universtiy School of Medicine, Daejeon (Korea, Republic of)

2013-12-15

229

Branched standard spines of 3-manifolds  

CERN Document Server

This book provides a unified combinatorial realization of the categroies of (closed, oriented) 3-manifolds, combed 3-manifolds, framed 3-manifolds and spin 3-manifolds. In all four cases the objects of the realization are finite enhanced graphs, and only finitely many local moves have to be taken into account. These realizations are based on the notion of branched standard spine, introduced in the book as a combination of the notion of branched surface with that of standard spine. The book is intended for readers interested in low-dimensional topology, and some familiarity with the basics is assumed. A list of questions, some of which concerning relations with the theory of quantum invariants, is enclosed.

Benedetti, Riccardo

1997-01-01

230

Indental gynecological findings on lumbar spine MRI  

International Nuclear Information System (INIS)

Female genital organs are partly visible on lumbar spine MRI. Uterus and/or ovaries were partly visualized in 100 out of 227 women. The examinations were performed at a 1,5 T system. In a group of 100 patients,the abnormalities of these organs were found in 38 cases.The following diagnoses were suggested:leiomyoma in 23 cases, adenomyosis in 3, deep endometrial endometriosis in 1,endometrial carcinoma in 4, Nabothian cyst in 8, simple ovarian cyst in 1, endometrial cyst in 1, dermoid cyst in 1, ovarian cancer in 1, fluid in Douglas ' pouch in 2. Lumbar spine MRI should be interpreted using unmagnified images, including the localizer series, because of frequent incidental gynecological findings in unaware women. (author)

2004-01-01

231

Upright positional MRI of the lumbar spine  

Energy Technology Data Exchange (ETDEWEB)

Supine magnetic resonance imaging (MRI) is routinely used in the assessment of low back pain and radiculopathy. However, imaging findings often correlate poorly with clinical findings. This is partly related to the positional dependence of spinal stenosis, which reflects dynamic changes in soft-tissue structures (ligaments, disc, dural sac, epidural fat, and nerve roots). Upright MRI in the flexed, extended, rotated, standing, and bending positions, allows patients to reproduce the positions that bring about their symptoms and may uncover MRI findings that were not visible with routine supine imaging. Assessment of the degree of spinal stability in the degenerate and postoperative lumbar spine is also possible. The aim of this review was to present the current literature concerning both the normal and symptomatic spine as imaged using upright MRI and to illustrate the above findings using clinical examples.

Alyas, F.; Connell, D. [London Upright MRI Centre, London (United Kingdom); Department of Radiology, Royal National Orthopaedic Hospital NHS Trust, Stanmore, Middlesex (United Kingdom); Saifuddin, A. [London Upright MRI Centre, London (United Kingdom); Department of Radiology, Royal National Orthopaedic Hospital NHS Trust, Stanmore, Middlesex (United Kingdom)], E-mail: asif.saifuddin@rnoh.nhs.uk

2008-09-15

232

Biomechanical Comparison Of Intact Lumbar Lamp Spine And Endoscopic Discectomized Lamp Spine  

Directory of Open Access Journals (Sweden)

Full Text Available Objectives: Purpose of current study was biomechanical comparison of changes wrought on motion segments after minimally invasive percutan endoscopic discectomized and intact spine. Materials and Methods: We prepared ten fresh-frozen lamb spines were used for this study. The spine of each specimen was dissected between L4-L5. The biomechanical tests for both intact spine and discectomized spine were performed by using axial compression testing machine (AG-I 10 kN, Shimadzu, Japanese. The axial compression was applied to all specimens with the loading speed of 5 mm/min. 8400 N/mm moment was applied to each specimen to achieve flexion and extension motions, right and left bending by a specially designed fixture. Results: In axial compression and flexion tests, the specimens were more stable according to displacement values. The displacement values of sectioned specimens were closer to intact specimens. Only displacement values of left-bending anteroposterior test for both situations were significant (0.05 ;#8805; P. Conclusion: PTED hasn't biomechanical and cilinical disadvantages. Endoscopic discectomy hadn't any disadvantages in stability. Only anterior-posterior displacement values of left bending test were statistically significant. We consider that cause of these results were due to the fact that all specimens had percutan transforaminal endoscopic discectomy (PTED from left side.

Ahmet Karakasli

2012-06-01

233

Glucose Sensing  

CERN Multimedia

Topics in Fluorescence Spectroscopy, Glucose Sensing is the eleventh volume in the popular series Topics in Fluorescence Spectroscopy, edited by Drs. Chris D. Geddes and Joseph R. Lakowicz. This volume incorporates authoritative analytical fluorescence-based glucose sensing reviews specialized enough to be attractive to professional researchers, yet also appealing to the wider audience of scientists in related disciplines of fluorescence. Glucose Sensing is an essential reference for any lab working in the analytical fluorescence glucose sensing field. All academics, bench scientists, and industry professionals wishing to take advantage of the latest and greatest in the continuously emerging field of glucose sensing, and diabetes care & management, will find this volume an invaluable resource. Topics in Fluorescence Spectroscopy Volume 11, Glucose Sensing Chapters include: Implantable Sensors for Interstitial Fluid Smart Tattoo Glucose Sensors Optical Enzyme-based Glucose Biosensors Plasmonic Glucose Sens...

Geddes, Chris D

2006-01-01

234

Airway management: Uncleared cervical spine injury  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The potential for cervical spine injury makes airway management more complex in the trauma patient. Patients with injury above the clavicles are at increased risk, and this is increased 4-fold if there is a clinically significant head injury (GCS < 9). Cervical vertebrae, being highly mobile for flexion, extension and rotation in vertebral column, are the most vulnerable ones for fracture, subluxation and dislocation. Atlanto-axial dislocation may even be fatal. In patients suspected for cerv...

2005-01-01

235

Fetal motor activity and spine development.  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The Authors, on the basis of previous data obtained by ultrasonography, analysed more closely the quantitative and qualitative correlations between movements and spine development in the human fetus. The bending angles of cervical lordosis and thoracic kyphosis showed a trend directly and inversely proportional, respectively, to the trend of the overall motility of the fetus, measured as the percentage of time employed by the fetus in motor activity. The trend of the lumbo-sacral angle, that ...

Panattoni, Gian Luigi; Todros, Tullia

1989-01-01

236

Titanium mesh cages (TMC) in spine surgery  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The introduction of the titanium mesh cage (TMC) in spinal surgery has opened up a variety of applications that are realizable as a result of the versatility of the implant. Differing applications of TMCs in the whole spine are described in a series of 150 patients. Replacement and reinforcement of the anterior column represent the classic use of cylindrical TMCs. The TMC as a multisegmental concave support in kyphotic deformities and as a posterior interlaminar spacer or lamina replacement a...

Grob, Dieter; Daehn, Sylvia; Mannion, Anne F.

2005-01-01

237

Treatment of metastases of the cervical spine.  

Science.gov (United States)

On the experience of 73 patients, the authors state their guidelines on the treatment of bone metastases on the cervical spine. Most of the cases on which no vertebral collapse occur neither neurological deficit, radiation therapy and external support are suggested. Surgery is necessary on case of severe bone destruction, collapse with or without subsequent neurological impairment. Anterior excision is considered the best approach, sometimes complemented by posterior stabilisation. PMID:9718821

Denaro, V; Gulino, G; Papapietro, N; Denaro, L

1998-01-01

238

Arachnoiditis ossificans of the thoracic spine.  

Science.gov (United States)

Arachnoiditis ossificans is a rare disorder characterized by the development of calcifications of the arachnoid membrane of the thoracic and lumbar spines. It is an extremely rare cause of spinal canal stenosis and consequent neurological compromise, and its origins and optimal management remain unclear. We review of the literature that illustrates the challenges of diagnosis and treatment of arachnoiditis ossificans. A patient with arachnoiditis ossificans is discussed to illustrate the presentation, treatment, and prognosis of the disease. PMID:24291474

Bagley, Jacob H; Ryan Owens, T; Grunch, Betsy H; Moreno, Jessica R; Bagley, Carlos A

2014-03-01

239

Remote Sensing  

...design; analytical methods, modeling, readout and software for sensors; sensor technology and new sensor principles Contribution: Special Issue: New Perspectives of Remote Sensing for Archaeology Dr. Jason K. Levy Homeland Security, National Homeland Security Project, L. Douglas Wilder School of Government and Public ...htm Interests: remote sensing for archaeology; Lidar; archaeogeophisics; non invasive tests for historical building Contribution: Special Issue: New Perspectives of Remote Sensing for Archaeology Dr. Pierre-Philippe Mathieu European Space Agency (ESRIN-EOP/SE), Earth Observation Science & Applications, ...

240

Normal CT anatomy of the spine  

International Nuclear Information System (INIS)

To analyse the anatomo-radiological correlation of the spine and spinal cord, 22 formalized, frozen anatomical specimens corresponding to different regions of the spinal column (8 cervical, 5 dorsal, and 9 lumbar) were studied by CT scans on axial, sagittal and coronal planes and by contact radiography after they were cut into anatomical slices in order to clarify the normal CT anatomy of the spinal column. The results obtained from CT patient scans, performed exclusively on the axial plane, were compared with those obtained from the anatomical specimens (both CT and contrast radiography). High resolution CT programs were used, enabling us to obtain better individualization of the normal structures contained in the spinal column. Direct sagittal and coronal sections were performed on the specimens in order to get further anatomo-radiological information. Enhanced CT studies of the specimens were also available because of the air already present in the subarachnoid spaces. Excellent visualization was obtained of bone structures, soft tissue and the spinal cord. High CT resolution of the spine appeares to be an excellent neuroradiological procedure to study the spine and spinal cord. A metrizamide CT scan is, however, necessary when a normal unenhanced CT scan is insufficient for diagnosis and when the spinal cord is not clearly visible, as often happens at the cervical level. Clinical findings are certainly very useful to ascertain the exact CT level and to limit the radiation exposure. (orig.)

1982-01-01

 
 
 
 
241

Clinical significance of gas myelography and CT gas myelography of the thoracic spine and the lumbar spine  

Energy Technology Data Exchange (ETDEWEB)

Basic and clinical applications relating to air myelography of the cervical spine have already been studied and extensively been used as an adjuvant diagnostic method for diseases of the spine and the spinal cord. However, hardly any application and clinical evaluation have been made concerning gas myelography of the thoracic spine and the lumbar spine. The author examined X-ray findings of 183 cases with diseases of the thoracic spine and the lumbar spine, including contral cases. Gas X-ray photography included simple profile, forehead tomography, sagittal plane, and CT section. Morphological characteristics of normal X-ray pictures of the throacic spine and the lumbar spine were explained from 54 control cases, and all the diameters of the subarachnoidal space from the anterior to the posterior part were measured. X-ray findings were examined on pathological cases, namely 22 cases with diseases of the throacic spine and 107 cases with diseases of the lumbar spine, and as a result these were useful for pathological elucidation of spinal cord tumors, spinal carries, yellow ligament ossification, lumbar spinal canal stenosis, hernia of intervertebral disc, etc. Also, CT gas myelography was excellent in stereo observation of the spine and the spinal cord in spinal cord tumors, yellow ligament ossification, and spinal canal stenosis. On the other hand, it is not suitable for the diagnoses of intraspinal vascular abnormality, adhesive arachinitis, and running abnormality of the cauda equina nerve and radicle. Gas myelography of the thoracic spine and the lambar spine, is very useful in clinics when experienced techniques are used in photographic conditions, and diagnoses are made, well understanding the characteristics of gas pictures. Thus, its application has been opened to selection of an operative technique, determination of operative ranges, etc.

Yoshinaga, Haruhiko (Tokyo Medical Coll. (Japan))

1984-05-01

242

Clinical significance of gas myelography and CT gas myelography of the thoracic spine and the lumbar spine  

International Nuclear Information System (INIS)

Basic and clinical applications relating to air myelography of the cervical spine have already been studied and extensively been used as an adjuvant diagnostic method for diseases of the spine and the spinal cord. However, hardly any application and clinical evaluation have been made concerning gas myelography of the thoracic spine and the lumbar spine. The author examined X-ray findings of 183 cases with diseases of the thoracic spine and the lumbar spine, including contral cases. Gas X-ray photography included simple profile, forehead tomography, sagittal plane, and CT section. Morphological characteristics of normal X-ray pictures of the throacic spine and the lumbar spine were explained from 54 control cases, and all the diameters of the subarachnoidal space from the anterior to the posterior part were measured. X-ray findings were examined on pathological cases, namely 22 cases with diseases of the throacic spine and 107 cases with diseases of the lumbar spine, and as a result these were useful for pathological elucidation of spinal cord tumors, spinal carries, yellow ligament ossification, lumbar spinal canal stenosis, hernia of intervertebral disc, etc. Also, CT gas myelography was excellent in stereoobservation of the spine and the spinal cord in spinal cord tumors, yellow ligament ossification, and spinal canal stenosis. On the other hand, it is not suitable for the diagnoses of intraspinal vascular abnormality, adhesive arachinitis, and running abnormality of the cauda equina nerve and radicle. Gas myelography of the thoracic spine and the lambar spine, is very useful in clinics when experienced techniques are used in photographic conditions, and diagnoses are made, well understanding the characteristics of gas pictures. Thus, its application has been opened to selection of an operative technique, determination of operative ranges, etc. (J.P.N.)

1984-01-01

243

Evaluation of Multi Canister Overpack (MCO) Handling Machine Uplift Restraint for a Seismic Event During Repositioning Operations  

International Nuclear Information System (INIS)

Insertion of the Multi-Canister Overpack (MCO) assemblies into the Canister Storage Building (CSB) storage tubes involves the use of the MCO Handling Machine (MHM). During MCO storage tube insertion operations, inadvertent movement of the MHM is prevented by engaging seismic restraints (''active restraints'') located adjacent to both the bridge and trolley wheels. During MHM repositioning operations, the active restraints are not engaged. When the active seismic restraints are not engaged, the only functioning seismic restraints are non-engageable (''passive'') wheel uplift restraints which function only if the wheel uplift is sufficient to close the nominal 0.5-inch gap at the uplift restraint interface. The MHM was designed and analyzed in accordance with ASME NOG-1-1995. The ALSTHOM seismic analysis reported seismic loads on the MHM uplift restraints and EDERER performed corresponding structural calculations to demonstrate structural adequacy of the seismic uplift restraint hardware. The ALSTHOM and EDERER calculations were performed for a parked MHM with the active seismic restraints engaged, resulting in uplift restraint loading only in the vertical direction. In support of development of the CSB Safety Analysis Report (SAR), an evaluation of the MHM seismic response was requested for the case where the active seismic restraints are not engaged. If a seismic event occurs during MHM repositioning operations, a moving contact at a seismic uplift restraint would introduce a friction load on the restraint in the direction of the movement. These potential horizontal friction loads on the uplift restraints were not included in the existing restraint hardware design calculations. One of the purposes of the current evaluation is to address the structural adequacy of the MHM seismic uplift restraints with the addition of the horizontal friction associated with MHM repositioning movements

2000-01-01

244

Spines of 3-Manifolds as Polyhedra with Identified Faces  

CERN Document Server

In this article we establish the relation between the spines of 3-manifolds and the polyhedra with identified faces. We do this by showing that the spines of the closed, connected, orientable 3-manifolds can be presented through polyhedra with identified faces in a very natural way. We also prove the equivalence between the special spines and a certain type of polyhedra, and other related results.

Isaza, Simón

2012-01-01

245

Efficacy and safety of instrumentation in caries spine  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Background: Spinal instrumentation may be used in tuberculosis of spine for prevention or correction of deformity. Methods: Thirty eight patients of caries spine underwent surgery with spinal instrumentation in the last 3 years. Out of these patients, 30 cases have completed a minimum follow-up of 9 months (Range 9 to 39 months, mean 12.8 months). The regional distribution was 1 in the craniocervical junction, 7 in the subaxial cervical spine, 3 in the cervicothoracic junctio...

2006-01-01

246

Automatic dendrite spines detection from X-ray tomography volumes  

Digital Repository Infrastructure Vision for European Research (DRIVER)

We consider the problem of dendritic spine detection from X-ray micro-tomographic volumes that allow huge volume of tissue visualization. To compensate for the noise in data that induces false positives in the spine detection process, we first segment the dendrites. This segmentation is obtained by computing the medial axis and approximating the results by segments obtained with a 3D Hough transform. Dendrites are then reconstructed and a spine mask is obtained using the typical diameter of d...

Descombes, Xavier; Malandain, Gre?goire; Fonta, Caroline; Negyessy, Lazlo; Mosko, Rajmund

2013-01-01

247

Lateral bone density measurements in osteoarthritis of the lumbar spine.  

Digital Repository Infrastructure Vision for European Research (DRIVER)

OBJECTIVE: To investigate whether spinal osteoarthritis (OA) is responsible for the common finding that lumbar spine bone mineral density (BMD) is greater when measured in the anteroposterior plane than when measured in the lateral plane. METHODS: We studied lateral spine radiographs from 63 women who attended a hospital outpatient department for bone density measurement and who also underwent lumbar spine radiography. Osteoarthritis was assessed using both the Kellgren and Lawrence scale and...

1996-01-01

248

Telangiectatic osteosarcoma of the spine: a case report  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Telangiectatic osteosarcoma (TOS) of the spine is rare accounting for only 0.08% of all primary osteosarcomas. Though a well described radio-pathological entity it is not often thought of as a cause of paraplegia. We describe the clinical, radiological and pathological features and discuss the treatment options of telangiectatic osteosarcoma of the dorsal spine presenting in a young man. The diagnostic pitfalls are discussed emphasising the fact that the diagnosis of TOS of the spine requires...

Amritanand, R.; Venkatesh, K.; Cherian, R.; Shah, A.; Sundararaj, G. D.

2008-01-01

249

Posterior transpedicular corpectomy for malignant cervical spine tumors  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The goal of this study was to assess surgical clinical and radiographic outcomes of using a posterior transpedicular approach (posterolateral) for ventral malignant tumors of the cervical spine. Access to ventral lesions of the cervical spine can be challenging in patients with malignant tumors. Anterior approaches are the gold standard for ventral pathology in the cervical spine, however, there are cases, where a posterior approach is indicated due to multilevel disease, previous radiation, ...

Eleraky, Mohammed; Setzer, Matthias; Vrionis, Frank D.

2010-01-01

250

Children's experiences of the repositioning of their psychological birth order in a reconstituted family / Lizelle van Jaarsveld.  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The aim of this study is to explore and describe children’s experiences of the repositioning of their psychological birth order in a reconstituted family. The aim of this study is also to contribute to a better understanding of this phenomenon to aid the parents of these children as well as professionals working with such families. The systems theory was used as the meta-theory of this study. Gestalt field theory formed the connection between the systems theory and Adlerian theory, to po...

Jaarsveld, Lizelle

2012-01-01

251

5 senses  

Science.gov (United States)

The students will learn how their senses work and what they use for each sense. This will help to cover the content standard 3: Students will develop an understanding of their environment. Parents I appreciate all the help you are giving to your child for them to complete this assignment. All the tasks which I will be having the children do will need to go right into the white sack I sent home with them. Also sorry about the commercials with the videos, I couldn't find a way to show them without those begin included. We all have 5 senses . These senses are taste, touch, sight, smell, and hearing . In order to better understand our environment we need to understand how to use our senses to explore it. I will have you go through a series of videos, definitions, and other resources ...

Anderson, Mrs.

2010-04-15

252

Spatiotemporal dynamics of dendritic spines in the living brain  

Science.gov (United States)

Dendritic spines are ubiquitous postsynaptic sites of most excitatory synapses in the mammalian brain, and thus may serve as structural indicators of functional synapses. Recent works have suggested that neuronal coding of memories may be associated with rapid alterations in spine formation and elimination. Technological advances have enabled researchers to study spine dynamics in vivo during development as well as under various physiological and pathological conditions. We believe that better understanding of the spatiotemporal patterns of spine dynamics will help elucidate the principles of experience-dependent circuit modification and information processing in the living brain.

Chen, Chia-Chien; Lu, Ju; Zuo, Yi

2014-01-01

253

Spatiotemporal Dynamics of Dendritic Spines in the Living Brain  

Directory of Open Access Journals (Sweden)

Full Text Available Dendritic spines are ubiquitous postsynaptic sites of most excitatory synapses in the mammalian brain, and thus may serve as structural indicators of functional synapses. Recent works have suggested that neuronal coding of memories may be associated with rapid alterations in spine formation and elimination. Technological advances have enabled researchers to study spine dynamics in vivo during development as well as under various physiological and pathological conditions. We believe that better understanding of the spatiotemporal patterns of spine dynamics will help elucidate the principles of experience-dependent circuit modification and information processing in the living brain.

YiZuo

2014-05-01

254

Staphylococcus aureus meningitis from osteomyelitis of the spine.  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Two cases of vertebral osteomyelitis presenting with secondary Staphylococcus aureus meningitis are described. In staphylococcal meningitis a search for a primary source should include the lower vertebral spine.

Markus, H. S.; Allison, S. P.

1989-01-01

255

Spine radiosurgery for spinal metastases: indications, technique and outcome.  

Science.gov (United States)

Early diagnosis, better imaging, and advanced treatment of cancer patients extend survival and increase the incidence of symptomatic spine metastases. The treatment algorithm for spine metastases has shifted to a more aggressive approach in recent years. Spine stereotactic radiosurgery (SRS) is a relatively new tool utilizing advanced imaging systems, planning software, image-guided localization, and intensity-modulated dose delivery. Radiosurgery of spine metastases yields high rates of pain- and tumor control, and offers both the patients and the treating physicians an effective noninvasive alternative. This review presents the indications and outcomes for SRS and describes current techniques. PMID:24725288

Harel, Ran; Zach, Leor

2014-06-01

256

Dosimetric implications of changes in patient repositioning and organ motion in conformal radiotherapy for prostate cancer  

International Nuclear Information System (INIS)

Purpose: To assess the influence of patient repositioning and organ motion on dose distribution within the prostate and the seminal vesicles (clinical target volume, (CTV)). Material and methods: Nine patients were simulated and treated in the supine position, with an empty bladder, and without immobilization devices. While on treatment, patients underwent weekly pelvic computed tomography (CT) scans under conditions identical to those at simulation. Patients were aligned using lasers on anterior and lateral skin tattoos, onto which lead markers were placed. After each CT scan (n=53) the CTV was redefined by contouring, and a new isocenter was obtained. A six-field technique was used. The field margins around the CTV were 20 mm in the cranio-caudal axis, and 13 mm in the other axes, except in the lateral fields where a 10 mm posterior margin was used. Dose-volume histograms (DVHs) for each organ were compared with those determined at simulation, using the notion of the proportional change in the area under the CTV-DVH curve resulting from a change in treatment plan (cDVH). Results: The reproducibility of the dose distribution was good for the prostate (%cDVH, mean±SD: -0.97±2.11%) and less than optimal for the seminal vesicles (%cDVH, mean±SD: -4.66±10.45%). When correlating prostate %cDVH variations with displacements of the isocenter in the Y axis (antero-posterior) the %cDVH exceeded (-)5% in only two dosimetries, both with an isocenter shift of >10 mm. For the seminal vesicles, however, ten out of 53 dosimetries showed a %cDVH exceeding (-) 5%. In nine of these ten dose distribution studies the posterior shift of the isocenter exceeded 8 mm. Conclusions: Precise targeting of prostate radiotherapy is primarily dependent on careful daily set-up and on random changes in rectal geometry. Margins no less than 10 mm around the prostate and at least 15 mm around the seminal vesicles are probably necessary to insure adequate target coverage with a six-field technique

2003-02-01

257

Lumbar spine degenerative disease : effect on bone mineral density measurements in the lumbar spine and femoral neck  

International Nuclear Information System (INIS)

To determine the effect of degenerative disease of the lumbar spine on bone mineral density in the lumbar spine and femoral neck. We reviewed radiographs and dual energy x-ray absorptiometry scans of the lumbar spine and hip in 305 Caucasian women with suspected osteoporosis. One hundred and eight-six patient remained after excluding women less than 40 years of age (n=18) and those with hip osteoarthritis, scoliosis, lumbar spine fractures, lumbar spinal instrumentation, hip arthroplasty, metabolic bone disease other than osteoporosis, or medications known to influence bone metabolism (n=101). On the basis of lumbar spine radiographs, those with absent/mild degenerative disease were assigned to the control group and those with moderate/severe degenerative disease to the degenerative group. Spine radiographs were evaluated for degenerative disease by two radiologists working independently; discrepant evaluations were resolved by consensus. Lumbar spine and femoral neck bone mineral density was compared between the two groups. Forty-five (24%) of 186 women were assigned to the degenerative group and 141 (76%) to the control group. IN the degenerative group, mean bone mineral density measured 1.075g/cm? in the spine and 0.788g/cm2 in the femoral neck, while for controls the corresponding figures were 0.989g/cm2 and 0.765g/cm2. Adjusted for age, weight and height by means of analysis of variance, degenerative disease of the lumbar spine was a significant predictor of increased bone mineral density in the spine (p=0.0001) and femoral neck (p=0.0287). Our results indicate a positive relationship between degenerative disease of the lumbar spine and bone mineral density in the lumbar spine and femoral neck, and suggest that degenerative disease in that region, which leads to an intrinsic increase in bone mineral density in the femoral neck, may be a good negative predictor of osteoporotic hip fractures

2001-04-01

258

49 CFR 572.75 - Lumbar spine, abdomen, and pelvis assembly and test procedure.  

Science.gov (United States)

...2009-10-01 2009-10-01 false Lumbar spine, abdomen, and pelvis assembly... 6-Year-Old Child § 572.75 Lumbar spine, abdomen, and pelvis assembly and test procedure. (a) Lumbar spine, abdomen, and pelvis...

2009-10-01

259

Evaluation and optimization of an image-subtraction method for the analysis of the repositioning accuracy of female patients with breast cancer  

International Nuclear Information System (INIS)

To analyze the repositioning accuracy in female patients with breast carcinoma, two different setups of an image-subtraction system (Positioning System FIVE) were devised using different numbers and alignments of lasers. The applicability of the system was tested for repositioning of the breast in normal volunteers. Horizontal translations as well as breathing-related movements in the vertical direction were measured. The mean repositioning accuracy was found to be 2.9 mm for the first setup and 1.5 mm for a second, optimized setup. For this second setup, a gating function was implemented which evaluates the position of the breast twelve times per second. The simulation of a gated treatment showed that the breathing-related displacement of the breast can be reduced to 45-70% of the displacement without gating. This implies a significant improvement of the positioning accuracy. (orig.)

2005-01-01

260

Traumatic thoracolumbar spine injuries: what the spine surgeon wants to know.  

Science.gov (United States)

The Thoracolumbar Injury Classification and Severity Score (TLICS) is a scoring and classification system developed by the Spine Trauma Study Group in response to the recognition that previous classification systems have limited prognostic value and generally do not suggest treatment pathways. The TLICS provides a spine injury severity score based on three components: injury morphology, integrity of the posterior ligamentous complex (PLC), and neurologic status of the patient. A numerical score is calculated for each category, with a lower point value assigned to a less severe or less urgent injury and a higher point value assigned to a more severe injury requiring urgent management. The total score helps guide decision making about surgical versus nonsurgical management. The TLICS also emphasizes the importance of magnetic resonance imaging in evaluating PLC injury and acknowledges that the primary driver of surgical intervention is the patient's neurologic status. Knowledge of PLC anatomy and its significance is essential in recognizing unstable injuries. Signs of PLC injury at computed tomography include interspinous distance widening, facet joint widening, spinous process fracture, and vertebral subluxation or dislocation. Familiarity with the TLICS will help radiologists who interpret spine trauma imaging studies to effectively communicate findings to spine trauma surgeons. The complete article is available online . PMID:24224597

Khurana, Bharti; Sheehan, Scott E; Sodickson, Aaron; Bono, Christopher M; Harris, Mitchel B

2013-01-01

 
 
 
 
261

Augmented reality visualization for thoracoscopic spine surgery  

Science.gov (United States)

We are developing an augmented reality (AR) image guidance system in which information derived from medical images is overlaid onto a video view of the patient. The centerpiece of the system is a head-mounted display custom fitted with two miniature color video cameras that capture the stereo view of the scene. Medical graphics is overlaid onto the video view and appears firmly anchored in the scene, without perceivable time lag or jitter. We have been testing the system for different clinical applications. In this paper we discuss minimally invasive thoracoscopic spine surgery as a promising new orthopedic application. In the standard approach, the thoracoscope - a rigid endoscope - provides visual feedback for the minimally invasive procedure of removing a damaged disc and fusing the two neighboring vertebrae. The navigation challenges are twofold. From a global perspective, the correct vertebrae on the spine have to be located with the inserted instruments. From a local perspective, the actual spine procedure has to be performed precisely. Visual feedback from the thoracoscope provides only limited support for both of these tasks. In the augmented reality approach, we give the surgeon additional anatomical context for the navigation. Before the surgery, we derive a model of the patient's anatomy from a CT scan, and during surgery we track the location of the surgical instruments in relation to patient and model. With this information, we can help the surgeon in both the global and local navigation, providing a global map and 3D information beyond the local 2D view of the thoracoscope. Augmented reality visualization is a particularly intuitive method of displaying this information to the surgeon. To adapt our augmented reality system to this application, we had to add an external optical tracking system, which works now in combination with our head-mounted tracking camera. The surgeon's feedback to the initial phantom experiments is very positive.

Sauer, Frank; Vogt, Sebastian; Khamene, Ali; Heining, Sandro; Euler, Ekkehard; Schneberger, Marc; Zuerl, Konrad; Mutschler, Wolf

2006-03-01

262

Percutaneous spine injection: considerations for improving treatment  

International Nuclear Information System (INIS)

To discuss the causes of treatment failure in percutaneous spine injections for low back pain or radiculopathy by analyzing patients who have experienced negative treatment effect on their first visit and a positive treatment effect on their second visit. The authors reviewed the cases of 24 patients who visited the pain intervention outpatient department in our hospital due to back pain or radiculopathy. All patients reviewed experienced a negative treatment effect following their first spine injection, but a positive treatment effect following the second injection. The dates of the cases range from June 2003 to May 2004. Two radiologists analyzed the possible causes of the negative treatment effect following the first injection therapies by considering clinical aspects as well as reviewing radiological images. The most common condition was the presence of the change in the level of the second selective nerve root block (n=13). In seven cases, the methods for administering the injections were changed to facet block (n=2), midline epidural block (n=1), selective nerve root block (n=3) and caudal epidural block (n=1). In four cases, there were no changes in the methods for administering the injections nor were there any changes in the level of the selective nerve root block between first and second visit. In those cases, after reviewing spot radiographs performed during injection, we attributed the causes of failure of injection therapy to an inappropriate distribution of drugs. We can improve the effect of percutaneous spine injections for low back pain or radioculopathy by determining the exact level of perineural root block, trying alternative methods, and insuring a good distribution of the injected drugs

2005-07-01

263

Blunt Traumatic Cervical Spine Fractures in Iran  

Directory of Open Access Journals (Sweden)

Full Text Available Background: Blunt traumatic cervical spine fractures (TCSF are serious injuries which may be associated with considerable mortality and morbidity. We describe the epidemiology of blunt traumatic cervical spine fracture in Iran over a definable time period. Methods: In a cross-sectional study, the data including the distribution of TCSF, demographics, mechanisms, abbreviated injury scale (AIS, spinal cord associated injuries and final outcome of patients, was extracted from the Iranian national trauma registry database in target hospitals in eight major cities of Iran from 1999 to 2004. The Chi square test was used to compare mortality and one-way ANOVA was used to compare ISS amongst the categories of TCSF. Results: TCSF was identified in 120 cases, of these 70.8% were male. Their mean age was 36.6 ± 17.2 years. The overall incidence of TCSF among all trauma patients was 0.7% (95%CI: 0.61% - 0.88%. The TCSF incidence among all spine fractured patients was 19.38% (95%CI: 16.34% - 22.72%. The most common mechanism of TCSF was a motor vehicle collision (66.7%. The overall percentage of in-hospital death for TCSF was 12.6%. There were no statistically significant difference in death and injury severity scores (ISS among TCSF categories (p > 0.05. Spinal cord and root injuries occurred in 34.9% and 2.4% of TCSF, respectively. Conclusions: Preventive strategies need to be developed in order to reduce the number and severity of TCSF in the general Iranian population.

Soheil Saadat

2011-10-01

264

Ocular VEMPs indicate repositioning of otoconia to the utricle after successful liberatory maneuvers in benign paroxysmal positioning vertigo  

Science.gov (United States)

Conclusions This study showed a transient increase of ocular vestibular evoked myogenic potential (oVEMP) amplitudes in the affected ear after successful liberatory maneuvers and no changes in cervical VEMP (cVEMP) amplitudes. These findings support the hypothesis that successful liberatory maneuvers can lead to a repositioning of otoconia to the utricle. Objectives To evaluate whether oVEMP amplitudes increase after successful liberatory maneuvers in patients with posterior semicircular canal benign paroxysmal positioning vertigo (pc-BPPV), while cVEMP amplitudes do not change. These findings may indicate a successful repositioning of dislodged otoconia to the utricular macula, but not to the saccular macula. Methods Thirty patients with unilateral pc-BPPV were prospectively examined with bone-conducted oVEMP and air-conducted cVEMP at four time points: before, after, 1 week after, and 1 month after the liberatory maneuvers (Sémont maneuvers). Results At the 1-week follow-up, 20 of 30 patients were asymptomatic (responders); BPPV could still be induced in the other 10 (non-responders). In responders the mean n10 amplitude on the affected side increased from 12 ± 6.5 ?V at baseline (before the treatment) to 15.9 ± 7.1 ?V at 1 week after treatment; this increase was significantly (p = 0.001) higher in responders than in non-responders. cVEMP did not differ significantly.

BREMOVA, TATIANA; BAYER, OTMAR; AGRAWAL, YURI; KREMMYDA, OLYMPIA; BRANDT, THOMAS; TEUFEL, JULIAN; STRUPP, MICHAEL

2014-01-01

265

A cost-outcome analysis of Image-Guided Patient Repositioning in the radiation treatment of cancer of the prostate  

International Nuclear Information System (INIS)

Background and purpose: With Image-Guided Radiation Therapy (IGRT) rapidly gaining acceptance in the clinic it is timely to commence an assessment of its potential outcome benefit versus costs. Materials and methods: Using Activity-Based Costing we have calculated the incremental cost of adding Image-Guided Patient Repositioning (IGPR), a significant component of IGRT, to both Intensity-Modulated Radiation Therapy (IMRT) and Three-Dimensional Conformal Radiation Therapy (3DCRT) for prostate cancer. The dosimetric outcome benefit resulting from the implementation of IGPR is estimated from a publication describing the improvement in set-up accuracy using each of four correction protocols. In our study outcome is quantified using a metric based on the Equivalent Uniform Dose. Our discussion is limited to image-guided corrective translations of the patient and does not specifically address margin reduction, rotations, organ deformation or major equipment failure modes, all of which are significant additional justifications for implementing an IGRT program. Results: Image guidance used solely for translational patient repositioning for prostate cancer adds costs with relatively little improvement in dosimetric quality. Full exploitation of the potential of IGRT, particularly through margin reduction, can be expected to result in a reduction in the cost-outcome ratios reported here. Conclusions: IMRT benefits more than 3DCRT from IGPR with the Weekly Shrinking Action Level approach yielding the lowest cost-outcome ratio.

2009-10-01

266

Repositioning of ETO gene in cells treated with VP-16, an inhibitor of DNA-topoisomerase II.  

Science.gov (United States)

The translocation t(8;21)(q22;q22) affecting AML1 and ETO genes is known to be one of the frequent chromosome translocations in acute myeloid leukemia. But no data have been available up to date concerning mutual positioning of these particular genes in the nucleus of a living cell as well as the mechanism of their rapprochement and realignment. Here we show that there is no proximity between these two genes in the primary nuclei of normal human male fibroblasts and moreover that these genes are located in different nuclear layers. But we further show that treatment of cells with VP-16 (etoposide), an inhibitor of DNA topoisomerase II widely used in anticancer chemotherapy, causes the ETO gene repositioning which allows AML1 and ETO genes to be localized in the same nuclear layer. Inhibitor studies demonstrate that such an effect is likely to be connected with the formation of stalled cleavable complexes on DNA. Finally, inhibition of ETO gene repositioning by 2,3-butanedione monoxime (BDM) suggests that this process depends on nuclear myosin. Together, our data corroborate the so called "breakage first" model of the origins of recurrent reciprocal translocation. PMID:18183572

Rubtsov, Mikhail A; Terekhov, Sergey M; Razin, Sergey V; Iarovaia, Olga V

2008-05-15

267

Incidence of venous thromboembolism after spine surgery  

International Nuclear Information System (INIS)

The incidence of venous thromboembolism (VTE) has varied among studies of patients undergoing elective spine surgery. This may be because of differences in prophylaxis for VTE and differences in methods of observation. Furthermore, some studies have reported symptomatic deep vein thrombosis (DVT) or pulmonary thromboembolism (PE), whereas others have included asymptomatic DVT or PE, making comparisons difficult. Therefore, the objective of this study was to determine the incidence of symptomatic and asymptomatic PE in patients undergoing elective spine surgery and to evaluate therapeutic methods for these conditions. The subjects were 1975 patients who underwent spine surgery in our hospital from 1990 to 2011. Patients treated from January 1990 to November 1996 (n=541, Group A) did not receive prophylaxis whereas those treated from January 2000 to February 2011 (n=1,434, Group B) used a foot pump during and after surgery and subsequently wore elastic stockings. All subjects in Group A began ambulation ?2 weeks after surgery whereas those in Group B began to walk earlier-within 3 days for patients who underwent decompression and within 1 week for those treated with fusion. From June 2010 to February 2011, contrast-enhanced computed tomography (CT) was performed 1 week after surgery for 100 patients to evaluate the presence of DVT and PE. Since March 2004, D-dimer was measured 1 week after surgery and patients with a level ?10 ?g/mL were followed up. The incidence of symptomatic PE was significantly higher in Group A than in Group B (8/541, 1.5% vs. 3/1,434, 0.2%). In 3 patients in Group B, PE developed within 1 week postoperatively and D-dimer values at onset were ?10 ?g/mL. In the 100 cases examined by contrast-enhanced computed tomography (CT), asymptomatic PE and VTE were detected in 18 and 19%, respectively. The D-dimer level 1 week after surgery was ?10 ?g/mL in 105 of 841 patients; however, none of these patients had clinically symptomatic VTE for at least 3 months postoperatively. Mechanical prophylaxis and early ambulation may be effective in reducing the incidence of symptomatic PE after spine surgery. Asymptomatic PE developed in 18% of patients who received mechanical prophylaxis, but the incidence of symptomatic PE was only 0.2%. Prompt diagnosis and treatment are required for patients who develop symptomatic PE. (author)

2012-03-01

268

Candida albicans osteomyelitis of the cervical spine  

Energy Technology Data Exchange (ETDEWEB)

Fungal osteomyelitis is a rare infection that usually develops in immunocompromised patients. Additionally, involvement of the cervical spine by Candida albicans is extremely rare; only three previous cases of Candida vertebral osteomyelitis have been reported in the literature. The diagnosis may be delayed due to nonspecific radiologic findings and a slow progression. We report the CT, MRI, bone scan, and PET-CT findings in a patient who developed Candida osteomyelitis, which was initially misdiagnosed as metastasis, at the atlas and axis following treatment for nasopharyngeal cancer. (orig.)

Cha, Jang-Gyu; Hong, Hyun-Sook [Soonchunhyang University Bucheon Hospital, Department of Radiology, Bucheon-Si, Gyeonggi-Do (Korea); Koh, Yoon-Woo [Soonchunhyang University Bucheon Hospital, Department of Otolaryngology - Head and Neck Surgery, Bucheon-Si, Gyeonggi-Do (Korea); Kim, Hee-Kyung [Soonchunhyang University Bucheon Hospital, Department of Pathology, Bucheon-Si, Gyeonggi-Do (Korea); Park, Jung-Mi [Soonchunhyang University Bucheon Hospital, Department of Nuclear Medicine, Bucheon-Si, Gyeonggi-Do (Korea)

2008-04-15

269

Candida albicans osteomyelitis of the cervical spine  

International Nuclear Information System (INIS)

Fungal osteomyelitis is a rare infection that usually develops in immunocompromised patients. Additionally, involvement of the cervical spine by Candida albicans is extremely rare; only three previous cases of Candida vertebral osteomyelitis have been reported in the literature. The diagnosis may be delayed due to nonspecific radiologic findings and a slow progression. We report the CT, MRI, bone scan, and PET-CT findings in a patient who developed Candida osteomyelitis, which was initially misdiagnosed as metastasis, at the atlas and axis following treatment for nasopharyngeal cancer. (orig.)

2008-04-01

270

Enlarged approach to the anterior cervical spine.  

Digital Repository Infrastructure Vision for European Research (DRIVER)

In this report a new enlarged approach to the anterior cervical spine is presented. A 66-year-old female, having a large C3-C4-C5 chordoma, recurrent after surgery and following radiotherapy, underwent a surgical resection. The approach allows a wide retraction of the nasopharynx, oropharynx and larynx from the midline, only sacrificing the superior laryngeal nerve on one side. Its continuity can be re-established later by adopting the stent in tube technique. The approach we used presents al...

Sartoris, Alberto; Crosetti, Erika; Succo, Giovanni

2001-01-01

271

Lumbar position sense acuity during an electrical shock stressor  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Optimal motor control of the spine depends on proprioceptive input as a prerequisite for co-ordination and the stability of the spine. Muscle spindles are known to play an important role in proprioception. Animal experiments suggest that an increase in sympathetic outflow can depress muscle spindle sensitivity. As the muscle spindle may be influenced by sympathetic modulation, we hypothesized that a state of high sympathetic activity as during mental stress would affect the proprioceptive output from the muscle spindles in the back muscles leading to alterations in proprioception and position sense acuity. The aim was to investigate the effect of mental stress, in this study the response to an electrical shock stressor, on position sense acuity in the rotational axis of the lumbar spine. Methods Passive and active position sense acuity in the rotational plane of the lumbar spine was investigated in the presence and absence of an electrical shock stressor in 14 healthy participants. An electrical shock-threat stressor lasting for approximately 12 minutes was used as imposed stressor to build up a strong anticipatory arousal: The participants were told that they were going to receive 8 painful electrical shocks however the participants never received the shocks. To quantify the level of physiological arousal and the level of sympathetic outflow continuous beat-to-beat changes in heart rate (beats*min-1 and systolic, diastolic and mean arterial blood pressure (mmHg were measured. To quantify position sense acuity absolute error (AE expressed in degrees was measured. Two-way analysis of variance with repeated measurements (subjects as random factor and treatments as fixed factors was used to compare the different treatments. Results Significant increases were observed in systolic blood pressure, diastolic blood pressure, and heart rate during the stress sessions indicating elevated sympathetic activity (15, 14 and 10%, respectively. Despite pronounced changes in the sympathetic activity and subjective experiences of stress no changes were found in position sense acuity in the rotational plane of the lumbar spine in the presence of the electrical shock stressor compared to the control period. Conclusion The present findings indicate that position sense acuity in the rotational plane of the spine was unaffected by the electrical shock stressor.

Fallentin Nils

2005-07-01

272

Fractionated stereotactic irradiation by Cyberknife of choroid melanomas: repositioning validation, closed eyelids; Irradiation stereotaxique fractionnee par Cyberknife des melanomes choroidiens: validation du repositionnement, paupieres fermees  

Energy Technology Data Exchange (ETDEWEB)

The fractionated stereotactic radiotherapy by Cyberknife is an option in the treatment of eyes tumors. The advantages of the Cyberknife in the choroid melanomas are in its infra-millimetric precision, to the automated repositioning on the skull bones and to the conformity brought by the stereotaxy. The objective of this study was to validate the quality of repositioning and the immobility of the eyes with closed eyelids. Conclusion: the reproducibility of the eye positioning with closed eyelids seems enough to consider the conservative treatment of choroid melanomas by fractionated stereotactic radiotherapy by Cyberknife without implementation of fiducials nor retrobulbar anaesthesia. (N.C.)

Horn, S.; Rezvoy, N.; Lacornerie, T.; Mirabel, X.; Labalette, P.; Lartigau, E. [Centre Oscar-Lambret, Service de Radiotherapie, 59 - Lille (France)

2009-10-15

273

Fractionated brain stereotactic radiotherapy: assessment of repositioning precision using a thermoforming mask; Radiotherapie stereotaxique cerebrale fractionnee: evaluation de la precision du repositionnement en utilisant un masque thermoformable  

Energy Technology Data Exchange (ETDEWEB)

The authors report a study which aimed at assessing the patient repositioning precision obtained with a support system used during a brain fractionated stereotactic radiotherapy and comprising a thermoforming mask (Elektra head mask). The repositioning is assessed by means of scano-graphies and superimposition with the stereotactic frame. A three-dimensional vector has been computed for each patient. The average displacement corresponds to that published in literature. The high quality of the support system allows a non invasive brain stereotactic radiotherapy to be performed which is also comfortable for the patient. Short communication

Barret, A.; Champeaux-Orange, E.; Bouscayrol, H.; Wachter, T. [CHR La Source, Orleans (France)

2011-10-15

274

Automated 4D analysis of dendritic spine morphology: applications to stimulus-induced spine remodeling and pharmacological rescue in a disease model  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Uncovering the mechanisms that regulate dendritic spine morphology has been limited, in part, by the lack of efficient and unbiased methods for analyzing spines. Here, we describe an automated 3D spine morphometry method and its application to spine remodeling in live neurons and spine abnormalities in a disease model. We anticipate that this approach will advance studies of synapse structure and function in brain development, plasticity, and disease.

Swanger Sharon A

2011-10-01

275

Surgical stabilization of the spine in the osteoporotic patient.  

Science.gov (United States)

Osteoporosis affects millions of US citizens, and millions more are at risk for developing the disease. Several operative techniques are available to the spine surgeon to provide care for those affected by osteoporosis. The types of osteoporosis, common surgical complications, medical optimization, and surgical techniques in the osteoporotic spine are reviewed, with an emphasis on preoperative planning. PMID:23544827

Dodwad, Shah-Nawaz M; Khan, Safdar N

2013-04-01

276

Some borderlands of the cervical spine. Pt. 1  

International Nuclear Information System (INIS)

The normal cervical spine may appear abnormal due to several factors, namely: The complexity of the cervical vertebra, the normal variation, the superimposition of the adjacent vertebrae, and the superimposition of structures outside the spine such as the craniofacial and laryngeal structures. (orig.)

1982-01-01

277

Clinical radiology of the spine and spinal cord  

International Nuclear Information System (INIS)

This book is a source of information about aspects of radiology of the spine and spinal column. It presents coverage of both normal and abnormal conditions. Contents: Spinal fractures and dislocations. Degenerative diseases of the spine. Gross anatomy of the spinal cord and meninges. Intraspinal mass lesions. Spinal dysraphism. Congenital anomalies. Tumors of the vertebral column, and more

1985-01-01

278

MR imaging of acute cervical spine injuries  

International Nuclear Information System (INIS)

To describe magnetic resonance (MR) findings of the patients with acute cervical spinal injury and to assess the usefulness of the MR imagings. We retrospectively reviewed the MR images of 32 patients with acute cervical spinal injury. MR images were obtained with a 2.0 T superconductive MR imaging units (Spectro-20000, Gold-Star, Seoul), using spin-echo and gradient-echo technique. Most of patients were in their 3rd-4th decades and motor vehicle accident was the most frequent cause of acute cervical trauma. We assessed the MR findings with respect to the spinal cord, ligaments, paravertebral soft tissues, intervertebral disk, and bony spine. Spinal cord injury was the most common (65%), where cord swelling, edema, and/or hematoma were demonstrated most frequently at C5-6 level. Traumatic intervertebral disk herniations were the second most common (62.5%) and frequently occurred at the lower cervical levels, mostly at C5-6. Paravertebral soft tissue injury, vertebral body fracture, bone marrow edema and displacement were also well shown on MR images. MR imaging appears to be essential for the evaluation of traumatic disk herniations, spinal cord abnormalities, and injury of paravertebral soft tissue in the acute injury of the cervical spine

1995-01-01

279

Working channel endoscope in lumbar spine surgery.  

Science.gov (United States)

Percutaneous endoscopic lumbar discectomy (PELD) is a well established modality in the treatment of patients with herniated lumbar discs. Since the time of its inception towards the end of 20th century, this technique has undergone significant modifications. With better understanding of the patho-anatomy and development of instrumentation the indications for PELD are on the rise. In the modern era of knowledge exchange there have been considerable variations among different endoscopic surgeons about classical indications and the implications of a particular technique pertaining to those indications. During last 15 years of experience in practicing endoscopic surgery, Choi has published many articles, regarding the techniques of PELD, across many scientific journals. In our practice there has been considerable shift from central debulking to discectomy to selective fragmentectomy. With further advancements the span of this technique is definitely on the rise. Here, we wish to share all the published data along with my current practice trends in more precise manner to help newer endoscopic spine surgeons understand the implications and limitations of a working channel endoscope in lumbar spine pathologies. PMID:24819484

Choi, G; Lee, S H; Deshpande, K; Choi, H

2014-06-01

280

Comparison of online IGRT techniques for prostate IMRT treatment: Adaptive vs repositioning correction  

International Nuclear Information System (INIS)

This study compares three online image guidance techniques (IGRT) for prostate IMRT treatment: bony-anatomy matching, soft-tissue matching, and online replanning. Six prostate IMRT patients were studied. Five daily CBCT scans from the first week were acquired for each patient to provide representative ''snapshots'' of anatomical variations during the course of treatment. Initial IMRT plans were designed for each patient with seven coplanar 15 MV beams on a Eclipse treatment planning system. Two plans were created, one with a PTV margin of 10 mm and another with a 5 mm PTV margin. Based on these plans, the delivered dose distributions to each CBCT anatomy was evaluated to compare bony-anatomy matching, soft-tissue matching, and online replanning. Matching based on bony anatomy was evaluated using the 10 mm PTV margin (''bone10''). Soft-tissue matching was evaluated using both the 10 mm (''soft10'') and 5 mm (''soft5'') PTV margins. Online reoptimization was evaluated using the 5 mm PTV margin (''adapt''). The replanning process utilized the original dose distribution as the basis and linear goal programming techniques for reoptimization. The reoptimized plans were finished in less than 2 min for all cases. Using each IGRT technique, the delivered dose distribution was evaluated on all 30 CBCT scans (6 patientsx5CBCT/patient). The mean minimum dose (in percentage of prescription dose) to the CTV over five treatment fractions were in the ranges of 99%-100%(SD=0.1%-0.8%), 65%-98%(SD=0.4%-19.5%), 87%-99%(SD=0.7%-23.3%), and 95%-99%(SD=0.4%-10.4%) for the adapt, bone10, soft5, and soft10 techniques, respectively. Compared to patient position correction techniques, the online reoptimization technique also showed improvement in OAR sparing when organ motion/deformations were large. For bladder, the adapt technique had the best (minimum) D90, D50, and D30 values for 24, 17, and 15 fractions out of 30 total fractions, while it also had the best D90, D50, and D30 values for the rectum for 25, 16, and 19 fractions, respectively. For cases where the adapt plans did not score the best for OAR sparing, the gains of the OAR sparing in the repositioning-based plans were accompanied by an underdosage in the target volume. To further evaluate the fast online replanning technique, a gold-standard plan (''new'' plan) was generated for each CBCT anatomy on the Eclipse treatment planning system. The OAR sparing from the online replanning technique was compared to the new plan. The differences in D90, D50, and D30 of the OARs between the adapt and the new plans were less than 5% in 3 patients and were between 5% and 10% for the remaining three. In summary, all IGRT techniques could be sufficient to correct simple geometrical variations. However, when a high degree of deformation or differential organ position displacement occurs, the online reoptimization technique is feasible with less than 2 min optimization time and provides improvements in both CTV coverage and OAR sparing over the position correction techniques. For these cases, the reoptimization technique can be a highly valuable online IGRT tool to correct daily treatment uncertainties, especially when hypofractionation scheme is applied and daily correction, rather than averaging over many fractions, is required to match the original plan.

2009-05-01

 
 
 
 
281

The Relationship between Recurrent Spine Surgery and Employment Status  

Directory of Open Access Journals (Sweden)

Full Text Available Background: What is the quantitative relationship between repeated surgical intervention and unemployment in the spine surgery population? And, does the literature pay sufficient attention to this important aspect of spine surgery outcome? Methods: This was a retrospective review of 905 patients of working age undergoing one of three types of spine surgery. The index surgery at the time of the study was either on the cervical or lumbar spine. We retrospectively collected data on patients’ employment status and history of prior spine surgery. In this study, history of prior spine surgery was coded using two nominal (categorical variables: The number of previous spine surgeries (0, 1, 2, ?3 and the variability of location of previous spine surgeries (cervical, lumbar. We also looked into scientific publications related to spine surgery and probed “employment” and “reoperation” awareness in randomized controlled trials (RCTs. In addition, we queried some common factors that are known to play an important role in exacerbating the unemployment problem, such as opioid (abuse and depression. Results: The unemployment rate was 19.4% among males and 34.8% among females. Unemployment rate correlated with the number of previous spine surgery (r = 0.077, p = 0.020, opioid use (r = 0.080, p = 0.017 and being on antidepressants (r = 0.119, p = 0.000. The unemployment rate was sta-tistically different (?2 = 10.656, p = 0.014 among patients with different numbers of previous spine surgeries: 25.6% of de novo patients versus 28.1% of patients with one previous spine surgery, 32.7% of patients with two previous spine surgeries and 48.7% of patients with three or more previous spine surgeries. Females had significantly higher unemployment rate if they had three or more previous spine surgeries in their past (31.4%, 34.4%, 46.2% versus 83.3%, ?2 = 21.841, p = 0.000. Unemployment rate was as high as 90% in female patients with ?3 surgeries on different regions of the spine and receiving antidepressants. Among randomized controlled trials addressing spine surgery in humans and published in English, 10.4% of reported studies mentioned opioids in their text, 4.1% (23/566 mentioned reoperation, 1.4% (8/566 mentioned employment, and none mentioned antidepressants. Conclusion: Females’ employment status is more sensitive to repeated surgical intervention, regardless of the part of the spine being targeted, reaching close to ten times the general population’s unemployment rate (83.3% versus 8%. On the other hand, a small percentage of randomized controlled trials pertaining to spine surgery deals with employment issues and reoperation rate in their outcome analysis.

Mohammad Sami Walid

2011-12-01

282

Maniobra de reposición canalítica para el tratamiento del vértigo postural paroxístico benigno Canalith reposition procedure for the treatment of benign paroxysmal positional vertigo  

Directory of Open Access Journals (Sweden)

Full Text Available Background: Paroxysmal positional vertigo is a frequent and handicapping disease. Aim: To assess the effectiveness of physical therapies using particle reposition procedures in the treatment of paroxysmal positional vertigo. Patients and methods: Fifty nine patients (13 male with paroxysmal positional vertigo were studied. Clinical data was gathered, the affected channel was identified. In the same session, the corresponding canalith reposition procedure was performed (Epley maneuver for posterior channel and Lempert maneuver for lateral channel and the immediate response was recorded. Results: Twenty seven percent of patients had recurring episodes of vertigo and 60% had more than two weeks of evolution. In 49% of patients, vertigo was considered idiopathic and in 92%, the posterior channel was affected. One patient had a combined lesion of posterior and lateral channels and two patients had isolated lateral channel lesions. Seventy percent of patients recovered after two sessions of canalith reposition procedure. Conclusions: Canalith reposition maneuvers were highly effective for the treatment of paroxysmal positional vertigo. (Rev Méd Chile 2000; 128: 619-26.

Viviana Valenzuela P

2000-06-01

283

Repositioning and Leaving In Situ the Central Venous Catheter During Percutaneous Treatment of Associated Superior Vena Cava Syndrome: A Report of Eight Cases  

International Nuclear Information System (INIS)

Purpose: To describe a combined procedure of repositioning and leaving in situ a central venous catheter followed by immediate percutaneous treatment of associated superior vena cava syndrome (SVCS). Methods: Eight patients are presented who have central venous catheter-associated SVCS (n = 6 Hickman catheters, n = 2 Port-a-cath) caused by central vein stenosis (n = 4) or concomitant thrombosis (n = 4). With the use of a vascular snare introduced via the transcubital or transjugular approach, the tip of the central venous catheter could be engaged, and repositioned after deployment of a stent in the innominate or superior vena cava. Results: In all patients it was technically feasible to reposition the central venous catheter and treat the SVCS at the same time. In one patient flipping of the Hickman catheter in its original position provoked dislocation of the released Palmaz stent, which could be positioned in the right common iliac vein. Conclusion: Repositioning of a central venous catheter just before and after stent deployment in SVCS is technically feasible and a better alternative than preprocedural removal of the vascular access

1999-05-01

284

Modeling the Effects of Moisture-Related Skin-Support Friction on the Risk for Superficial Pressure Ulcers during Patient Repositioning in Bed  

Directory of Open Access Journals (Sweden)

Full Text Available Patient repositioning when the skin is moist e.g. due to sweat or urine may cause skin breakdown since wetness increases the skin-support coefficient of friction (COF and hence also the shear stresses that are generated in the skin when the patient is being moved. This everyday hospital scenario was never studied systematically however. The aim of this study was to simulate such interactions using a biomechanical computational model which is the first of its kind, in order to quantitatively describe the effects of repositioning on the pathomechanics of moisture-related tissue damage. We designed a finite element model to analyze skin stresses under a weight-bearing bony prominence while this region of interest slides frictionally over the support surface, as occurs during repositioning. Our results show, expectedly, that maximal effective stresses in the skin increase as the moisture-contents-related COF between the skin and the mattress rises. Interestingly however, the rise in stresses for a wet interface became more prominent when the skin tissue was stiffer - which represented aging or diabetes. This finding demonstrates how the aged/diabetic skin is more fragile than a young-adult skin when repositioning in a moist environment. The modeling used herein can now be extended to test effects of different moisturizers, creams, lubricants or possibly other interventions at the skin-support interface for testing their potential in protecting the skin from superficial pressure ulcers in a standard, objective and quantitative manner.

AmitGefen

2013-10-01

285

Anatomical and functional perspectives of the cervical spine: Part I: the “normal” cervical spine †  

Digital Repository Infrastructure Vision for European Research (DRIVER)

This is the first of a three part series describing the clinical issues surrounding the radiographic assessment of the cervical spine. Defined in this literature review is the working definition of cervical stability. Described are the “normal” anatomical relationships between the cervical vertebrae for both the adult and the child, as portrayed by lateral radiographs. Also presented is a review of available documentation regarding the normal segmental function of the vertebrae in the upp...

1989-01-01

286

Top 20 cited Spine Journal articles, 1990-2009  

Science.gov (United States)

AIM: To determine the most cited articles and most published authors in Spine Journal from 1990-2009. METHODS: Spine Journal, established in 1976, is affiliated with 12 spine societies and a leader in spine research articles. Citation analysis is a method to determine the impact of a journal and its articles on academia and clinical practice. Using the Institute for Scientific Information Web of Knowledge, we determined the most cited articles in Spine Journal between1990-2009. The characteristics and type of article were recorded. Next, we evaluated the most published authors during the same time period and calculated the number of citations for each author. The number of first authorships for each of these authors was also determined along with the number of citations for those articles. RESULTS: The top 20 cited articles range from 491 to 267 total citations. The top 20 published authors had between 41 and 135 articles. Seventeen of the top 20 articles were clinical studies. The range of citations per lead authorship ratio was 36 to 724 with one author having no lead authorships. Low back pain was the most common theme encountered in the top cited articles. The first-ranked article was not a spine-specific topic rather it was regarding general physical and mental health status survey update review. CONCLUSION: Spine Journal and its authors have a clear impact on the scientific community based on this review of the top articles and authors in the last 20 years.

Elgafy, Hossein K; Miller, Jacob D; Hashmi, Sohaib; Ericksen, Steven

2014-01-01

287

MRI features of hydatid disease of the spine  

International Nuclear Information System (INIS)

Objective: To analyze the typical MRI findings and to evaluate the value of MRI in the diagnosis of hydatid disease of the spine. Methods: This retrospective study consisted of 16 patients with hydatidosis of the spine evaluated with MRI. All patients had surgery with histological diagnosis. MR myelography (MRM) was done in 4 eases, contrast-enhanced scan in 2 cases and perfusion weighted imaging (PWI) in 1 case. X-ray was performed in 8 cases and CT in 5 cases. Results: All 16 cases were diagnosed as hydatid disease with multicysts. Hydatid disease involved thoracic spine in 5 cases, lumbar spine in 4 cases, sacrum in 3 eases, lumbosacral spine in 2 cases and a combination of thoracic, lumbar spine and sacrum in 2 cases. MR imaging showed bone destruction with wedge shaped compression of single or multiple vertebra. The lesions were round in contour with different sizes and involved the bony spinal canal, appendix of vertebra and neighboring soft tissues. Cystic lesions with multiple daughter cysts demonstrated long T1 and long T2 abnormal signal intensity on MR imaging. On T2-weighted images, a hypointense rim was seen. Cystic lesions were better seen on T2 SPIR and MRM. Mild contrast enhancement of these lesions were seen. A single case showed iso-perfusion on PWI. Conclusions: MRI can demonstrate hydatid cysts in vertebra, spinal canal, paravertebral and neighboring soft tissue. MRI is a valuable tool in the diagnosis and treatment planning of hydatid disease of the spine. (authors)

2009-08-01

288

MRI of cervical spine injuries complicating ankylosing spondylitis  

Energy Technology Data Exchange (ETDEWEB)

The objective was to study characteristic MRI findings in cervical spine fractures complicating ankylosing spondylitis (AS). Technical issues related to MRI are also addressed. A review of 6,774 consecutive cervical spine multidetector CT (MDCT) scans obtained during 6.2 years revealed 33 ankylosed spines studied for suspected acute cervical spine injury complicating AS. Of these, 20 patients also underwent MRI. On MRI, of these 20 patients, 19 had a total of 29 cervical and upper thoracic spine fractures. Of 20 transverse fractures traversing both anterior and posterior columns, 7 were transdiskal and exhibited less bone marrow edema than did those traversing vertebral bodies. One Jefferson's, 1 atlas posterior arch (Jefferson's on MDCT), 2 odontoid process, and 5 non-contiguous spinous process fractures were detectable. MRI showed 2 fractures that were undetected by MDCT, and conversely, MDCT detected 6 fractures not seen on MRI; 16 patients had spinal cord findings ranging from impingement and contusion to complete transection. Magnetic resonance imaging can visualize unstable fractures of the cervical and upper thoracic spine. Paravertebral hemorrhages and any ligamentous injuries should alert radiologists to seek transverse fractures. Multiple fractures are common and often complicated by spinal cord injuries. Diagnostic images can be obtained with a flexible multipurpose coil if the use of standard spine array coil is impossible due to a rigid collar or excessive kyphosis. (orig.)

Koivikko, Mika P.; Koskinen, Seppo K. [Helsinki Medical Imaging Center, Helsinki University Central Hospital, Toeoeloe Hospital, Department of Radiology, Helsinki (Finland)

2008-09-15

289

N-cadherin, spine dynamics, and synaptic function  

Directory of Open Access Journals (Sweden)

Full Text Available Dendritic spines are one half (the postsynaptic half of most excitatory synapses. Ever since the direct observation over a decade ago that spines can continually change size and shape, spine dynamics has been of great research interest, especially as a mechanism for structural synaptic plasticity. In concert with this ongoing spine dynamics, the stability of the synapse is also needed to allow continued, reliable synaptic communication. Various cell-adhesion molecules help to structurally stabilize a synapse and its proteins. Here, we review the effects of disrupting N-cadherin, a prominent trans-synaptic adhesion molecule, on spine dynamics, as reported in Mysore et al., (2007. We highlight the novel method adopted therein to reliably detect even subtle changes in fast and slow spine dynamics. We summarize the structural, functional, and molecular consequences of acute N-cadherin disruption, and tie them in, in a working model, with longer-term effects on spines and synapses reported in the literature.

ShreeshPMysore

2008-12-01

290

Effect of the Mandibular Orthopedic Repositioning Appliance (MORA) on Forearm Muscle Activation and Grasping Power during Pinch and Hook Grip  

Science.gov (United States)

[Purpose] This study verified the changes in muscle activities and grasping power during maximal isometric exercise of the forearm and masseter muscle with and without a mandibular orthopedic repositioning appliance (MORA). It also offers basic data for defining the correlation of function of hand with mouth. [Methods] EMG was used to measure masticatory muscle, flexor bundle and extensor bundle activities with or without MORA while subjects performed the hook grip and pinch grip. The measuring tool used for measuring grip strength was the same as that used for measuring pinch and hook strength. The subjects were 28 healthy young adults. [Result] Muscle activity and grasping power significantly increased when wearing the MORA. [Conclusion] The result indicates that wearing MORA can increase muscle activity and grasping power of forearm and masseter muscle. We think wearing MORA might help improve the function of the forearm because it activates the function of the masseter.

Lee, Sang-Yeol; Park, Yi-Jeong; Park, Hye-Min; Bae, Hae-Jin; Yu, Min-Ji; Choi, Hee-Won; Hwang, Na-Young

2014-01-01

291

Precision assessment of osteoporosis from spine radiographs  

International Nuclear Information System (INIS)

Inter- and intra-observer variation in spine radiographs of 100 osteoporotic women and longitudinal change in roentgenologic status after 1 year of anti-osteoporotic treatment were assessed. The method applied was naked eye inspection, and a score system estimating severity of fractures-vertebral deformation score (VDS). Agreement was assessed by the Kappa coefficient corrected for agreement by change. The results showed a satisfactory inter- and intra-observer agreement for wedge (Kappa=0.72 and 0.90) and compression fractures (Kappa=0.60 and 0.92). The method proved less reliable for endplate fractures (Kappa=0.39 and 0.73). The authors think that the method of investigation is well suited for monitoring treatment effects in longitudinal studies. (author). 16 refs.; 1 fig.; 2 tabs

1991-01-01

292

Nuclear magnetic resonance imaging of the spine  

International Nuclear Information System (INIS)

Forty subjects were examined to determine the accuracy and clinical usefulness of nuclear magnetic resonance (NMR) examination of the spine. The NMR images were compared with plain radiographs, high-resolution computed tomograms, and myelograms. The study included 15 patients with normal spinal cord anatomy and 25 patients whose pathological conditions included canal stenosis, herniated discs, metastatic tumors, primary cord tumor, trauma, Chiari malformations, syringomyelia, and developmental disorders. Saturation recovery images were best in differentiating between soft tissue and cerebrospinal fluid. NMR was excellent for the evaluation of the foramen magnum region and is presently the modality of choice for the diagnosis of syringomyelia and Chiari malformation. NMR was accurate in diagnosing spinal cord trauma and spinal canal block

1984-01-01

293

Nuclear magnetic resonance imaging of the spine  

Energy Technology Data Exchange (ETDEWEB)

Forty subjects were examined to determine the accuracy and clinical usefulness of nuclear magnetic resonance (NMR) examination of the spine. The NMR images were compared with plain radiographs, high-resolution computed tomograms, and myelograms. The study included 15 patients with normal spinal cord anatomy and 25 patients whose pathological conditions included canal stenosis, herniated discs, metastatic tumors, primary cord tumor, trauma, Chiari malformations, syringomyelia, and developmental disorders. Saturation recovery images were best in differentiating between soft tissue and cerebrospinal fluid. NMR was excellent for the evaluation of the foramen magnum region and is presently the modality of choice for the diagnosis of syringomyelia and Chiari malformation. NMR was accurate in diagnosing spinal cord trauma and spinal canal block.

Modic, M.T.; Weinstein, M.A.; Pavlicek, W.; Starnes, D.L.; Duchesneau, P.M.; Boumphrey, F.; Hardy, R.J. Jr.

1984-01-01

294

Tophaceous pseudogout of the thoracic spine.  

Science.gov (United States)

Calcium pyrophosphate dihydrate deposition disease (CPDD, tophaceous pseudogout) is a rare crystal arthropathy characterized by pyrophosphate crystal deposition in joints, synovitis and chondrocalcinosis on imaging. We present the case of a 72-year-old man with 6 months of left chest pain; magnetic resonance imaging revealed a T9/T10 herniated disc. Intraoperatively, the material was sent for pathological analysis revealing pseudogout. Axial calcium pyrophosphate crystal deposition is rare but reported in the literature and found at the craniocervical junction and skull. Spinal calcium pyrophosphate crystal deposition is rare in the thoracic spine. It is often asymptompatic and can involve the disc or ligaments. This case demonstrates a unique presentation of CPDD. PMID:22367409

Srinivasan, Vasisht; Kesler, Henry; Johnson, Mahlon; Dorfman, Howard; Walter, Kevin

2012-04-01

295

MR imaging evaluation of congenital spine anomalies  

International Nuclear Information System (INIS)

Over a 2-year period, 135 patients between the ages of 1 week and 18 years were examined with MR imaging for possible congenital anomalies of the spine and spinal cord. Tethered cords with various other associated pathologies such as lipomas and myelomeningoceles were found in 36 patients. The remaining abnormal examinations consisted of syrinxes, Chiari malformations, diastematomyelia, and conus masses. In 55 patients the studies were interpreted as normal. Of these, three were subsequently shown by surgery of myelography to be abnormal. The first had a thickened filum with a small epidermoid, the second a thickened filum, and the third, with only sagittal images, a diastematomyelia. Children presenting with symptoms highly suspicious for congenital abnormalities but with a normal MR study in multiple planes may still require further evaluation with myelography. Multiplanar MR examination in most instances will be a sufficient evaluation for congenital anomalies

1987-12-04

296

Spondylitis of thoracic spine: Case report  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction Spondylitis is a rare bone and joint infection. It is a disease with long clinical history. Often, it is difficult to recognise symptoms at a proper time, and, due to the complex clinical outcome of spondylitis, a clinician may think about other problems in the body. Case Outline A case report of a 59-year-old male patient with thoracic spine spondylitis is presented, formerly treated as pulmonary thromboembolism with pericarditis. Only after neurological disorder such as paraplegia and orthopaedic consultative examination, real diagnosis was established. After that, the patient was hospitalized and operated on. Conclusion A therapeutic approach to spondylitis is based on surgery, antibiotic drugs and symptomatic therapy. Due to the frequent occurrence of neurologic disorders, therapy could be prolonged and uncertain. .

Timotijevi? Sla?an

2008-01-01

297

NMR in the SPINE Structural Proteomics project.  

Science.gov (United States)

This paper describes the developments, role and contributions of the NMR spectroscopy groups in the Structural Proteomics In Europe (SPINE) consortium. Focusing on the development of high-throughput (HTP) pipelines for NMR structure determinations of proteins, all aspects from sample preparation, data acquisition, data processing, data analysis to structure determination have been improved with respect to sensitivity, automation, speed, robustness and validation. Specific highlights are protonless (13)C-direct detection methods and inferential structure determinations (ISD). In addition to technological improvements, these methods have been applied to deliver over 60 NMR structures of proteins, among which are five that failed to crystallize. The inclusion of NMR spectroscopy in structural proteomics pipelines improves the success rate for protein structure determinations. PMID:17001092

Ab, E; Atkinson, A R; Banci, L; Bertini, I; Ciofi-Baffoni, S; Brunner, K; Diercks, T; Dötsch, V; Engelke, F; Folkers, G E; Griesinger, C; Gronwald, W; Günther, U; Habeck, M; de Jong, R N; Kalbitzer, H R; Kieffer, B; Leeflang, B R; Loss, S; Luchinat, C; Marquardsen, T; Moskau, D; Neidig, K P; Nilges, M; Piccioli, M; Pierattelli, R; Rieping, W; Schippmann, T; Schwalbe, H; Travé, G; Trenner, J; Wöhnert, J; Zweckstetter, M; Kaptein, R

2006-10-01

298

Thoracoscopy for minimally invasive thoracic spine surgery.  

Science.gov (United States)

Thoracoscopy has been used worldwide for many years by thoracic surgeons. Despite a long learning curve and technical demands of the procedure, thoracoscopy has several advantages, including better cosmesis, adequate exposure to all levels of the thoracic spine from T2 to L 1, better illumination and magnification at the site of surgery, less damage to the tissue adjacent to the surgical field, less morbidity when compared with standard thoracotomy in terms of respiratory problems, pain, blood loss, muscle and chest wall damages, consequent shorter recovery time, less postoperative pulmonary function impairment, and shorter hospitalization. Good results at short- and medium-term follow-up need to be confirmed at long-term follow-up. PMID:19773050

Longo, Umile Giuseppe; Papapietro, Nicola; Maffulli, Nicola; Denaro, Vincenzo

2009-10-01

299

Introduction: minimally invasive spine surgery video supplement.  

Science.gov (United States)

This video supplement of Neurosurgery Focus is devoted to minimally invasive spine surgery. Minimally invasive spine surgery has gained popularity amongst patients and physicians over the past decade because it has been shown in select instances to lower blood loss and reduce length of hospital stay for appropriately selected candidates. This supplement includes videos from many of the leaders in the field. Pioneers like Frank LaMarca, Paul Park, Cheerag Upadhyaya, Juan Uribe, and Mike Wang have all sent in videos depicting minimally invasive spinal deformity surgery options. The supplement also includes videos from several different countries, demonstrating how widespread and nuanced minimally invasive spinal procedures have become. Drs. Barbagallo, Certo, Sciacca, and Albanese from Italy; Drs. Gragnaniello and Seex from Australia; and Drs. Liao, Wu, Huang, Wang, Chang, Cheng, and Shih from Taiwan have all sent in nuanced surgical videos that will be of interest to many viewers. I personally enjoyed viewing videos on lumbar degenerative disease surgery depicting unique surgical nuances to treat common problems. Dr. Beejal Amin, Dr. Harel Deutsch, Dr. Daniel Lu, and Dr. Adam Kanter have each submitted videos depicting lumbar decompression and/or fusion for lumbar degenerative stenosis and spondylosis. This supplement also included videos depicting the minimally invasive treatment of uncommon spinal pathologies as well. Videos from Dr. Fred Geisler, Dr. John O'Toole, and Dr. Noel Perin covered topics as varied as sacroiliac joint dysfunction, spinal arteriovenous malformations, and sympathetic chain surgery. I hope that you enjoy this issue of Neurosurgical Focus devoted to videos depicting the surgical nuances of minimally invasive spinal surgery. This video supplement has international appeal, and it has been an honor to be a guest editor on this superb supplement. PMID:23829838

Mummaneni, Praveen V

2013-07-01

300

Infections of the spine; Infektionen der Wirbelsaeule  

Energy Technology Data Exchange (ETDEWEB)

Diagnosis of infectious disease of the spine in an early stage ist difficult. Conventional X-ray examinations, often used as a basic screening study, will show the characteristic narrowing of the intervertebral disc space and the osteolytic and sclerotic changes in the adjointing vertebra only after two to eight weeks. Magnetic resonance imaging (MRI) has a sensitivity equivalent to bone scintigraphy and, due to its superior delineation of anatomic details, MRI has become the method of choice not only for the assessment of location, extent, and associated lesions in infectious bone disease, but also in the diagnosis of intradural infections including myelitis. MRI examination in the assessment of a successful therapy or osteomyelitis of the spine aims for the detection of regression of bone marrow edema, reappearance of fatty marrow, and less pronounced contrast enhancement. Computed tomography (CT) is mainly used for image-guided biopsy to obtain specimen for microbiologic culture or for the placement of a percutaneous drainage. (orig.) [Deutsch] Die Diagnostik entzuendlicher Erkrankungen der Wirbelsaeule und des Spinalkanals in den Fruehstadien ist schwierig. Die als Einstiegsdiagnostik eingesetzte Nativroentgenaufnahme zeigt bei der Spondylitis fruehestens 2 bis 8 Wochen nach Infektion die charakteristische Hoehenminderung des Zwischenwirbelraums, die von lytischen und sklerotischen Veraenderungen der benachbarten Wirbelkoerper begleitet wird. Die Magnetresonanztomographie (MRT) ist heute aufgrund ihrer der Szintigraphie vergleichbar hohen Sensitivitaet und ihrer ueberlegenen anatomischen Detailaufloesung Untersuchungsmethode der Wahl nicht nur zur Beurteilung von Lage, Groesse und Umgebungsreaktion entzuendlicher Knochenprozesse, sondern auch bei der Diagnostik intraduraler Infektionen einschliesslich der Myelitis. Parameter zur Beurteilung einer erfolgreichen Therapie von Wirbelsaeulenosteomyelitiden in der MRT sind die Rueckbildung des Knochenmarkoedems, die Fettmarkkonversion und der Rueckgang der Kontrastmittelanfaerbung. Das Hauptanwendungsgebiet der Computertomographie ist bei schon diagnostiziertem Krankheitsbild die Biopsie zum Erregernachweis und gegebenenfalls therapeutisch die gezielte Plazierung einer Drainage. (orig.)

Heindel, W. [Koeln Univ. (Germany). Inst. und Poliklinik fuer Radiologische Diagnostik; Lanfermann, H. [Koeln Univ. (Germany). Inst. und Poliklinik fuer Radiologische Diagnostik; Du Mesnil, R. [Koeln Univ. (Germany). Inst. und Poliklinik fuer Radiologische Diagnostik; Fischbach, R. [Koeln Univ. (Germany). Inst. und Poliklinik fuer Radiologische Diagnostik

1996-11-01

 
 
 
 
301

Papillary muscle repositioning as a subvalvular apparatus preservation technique in mitral stenosis patients with normal left ventricular systolic function.  

Science.gov (United States)

Subvalvular apparatus preservation is an important concept in mitral valve replacement (MVR) surgery that is performed to remedy mitral regurgitation. In this study, we sought to determine the effects of papillary muscle repositioning (PMR) on clinical outcomes and echocardiographic left ventricular function in rheumatic mitral stenosis patients who had normal left ventricular systolic function. We prospectively assigned 115 patients who were scheduled for MVR surgery with mechanical prosthesis to either PMR or MVR-only groups. Functional class and echocardiographic variables were evaluated at baseline and at early and late postoperative follow-up examinations. All values were compared between the 2 groups. The PMR group consisted of 48 patients and the MVR-only group of 67 patients. The 2 groups' baseline characteristics and surgery-related factors (including perioperative mortality) were similar. During the 18-month follow-up, all echocardiographic variables showed a consistent improvement in the PMR group; the mean left ventricular ejection fraction deteriorated significantly in the MVR-only group. Comparison during follow-up of the magnitude of longitudinal changes revealed that decreases in left ventricular end-diastolic and end-systolic diameters and in left ventricular sphericity indices, and increases in left ventricular ejection fractions, were significantly higher in the PMR group than in the MVR-only group. This study suggests that, in patients with rheumatic mitral stenosis and preserved left ventricular systolic function, the addition of papillary muscle repositioning to valve replacement with a mechanical prosthesis improves left ventricular dimensions, ejection fraction, and sphericity index at the 18-month follow-up with no substantial undesirable effect on the surgery-related factors. PMID:24512397

Lafci, Gokhan; Cagli, Kerim; Cicek, Omer Faruk; Korkmaz, Kemal; Turak, Osman; Uzun, Alper; Yalcinkaya, Adnan; Diken, Adem; Gunertem, Eren; Cagli, Kumral

2014-02-01

302

The Relationship of SmokingOpioidAntidepressant Use and History of Spine Surgery  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction: In a recent paper, smoking was shown to be an independent predictor of longterm continued opioid use in spine patients (Krebs et al. 2010. In this paper, we study the interaction of smoking with opioid and antidepressant use and the relationship with prior spine surgery and future spine surgery. Methods: Data on smoking, opioid and antidepressant use were retrospectively collected from 758 spine surgery inpatients [lumbar microdiskectomy (LMD, anterior cervical decompression and fusion (ACDF and lumbar decompression and fusion (LDF]. Interaction with history of previous spine surgery and return for additional spine surgery was studied. Followup ranged from one to four years. Results: Significant correlation was detected between smoking and opioid use and between opioid and antidepressant use. History of previous spine surgery correlated with antidepressant use and return for additional spine surgery. Additional spine surgery correlated with opioid use and history of previous spine surgery. Smoking LMD patients on both opioids and antidepressants and smoking ACDF patients on antidepressants who have a history of prior spine surgery were more likely to return for additional spine surgery. However, in the LDF group, smoking patients on antidepressants without previous spine surgery were more likely to come for another spine surgery. Conclusion: Smokingantidepressantopioid use could be predictive of return for additional spine surgery during the followup years especially if a history of prior spine surgery was reported. Further research is needed on the implications of such an association.

Walid Mohammad

2010-08-01

303

Osteoid Osteoma of Cervical Spine in two adjacent Vertebrae  

Directory of Open Access Journals (Sweden)

Full Text Available Osteoid osteoma is a benign bone tumor, mainly seen in 10-30 years male. Spine is a relatively common site and almost always, posterior elements are involved. Plain X-Ray-, CT scan and Isotope scan help to identify and localize spine lesions. We described one 18 years old boy with 3 years low neck pain. Isotope scan, MRI and CT scan showed two lesions in C7 and T1. Gross inspection and histopathology examination confirmed osteoid osteoma in two adjacent vertebrae which has not been reported elsewhere in the literature. Key words: Osteoid Osteoma, Spine, Multifocal

MR Etemadifar

2005-09-01

304

Efficacy of gated image acquisition in sagittal MR spine studies  

International Nuclear Information System (INIS)

The objective of this study was to evaluate the efficacy and efficiency of cerebrospinal fluid (CSF)-gated MR data acquisition during sagittal lumbar spine examinations. In spine phantom studies, CSF pulsation amplitudes of only 2-3 mm degraded CSF-thecal sac conspicuity on nongated images but not on gated images. Gated (effective TR = l,600-1,700 msec) and ungated (TR = 2,000-2,500 msec) sagittal lumbar spine examinations performed on 20 patients were evaluated for signal-to-noise ratio and CSF contrast. CSF-gated imaging was faster and resulted in increased CSF contrast, compared to the nongated images

1986-12-05

305

A global CT to US registration of the lumbar spine  

Science.gov (United States)

During percutaneous lumbar spine needle interventions, alignment of the preoperative computed tomography (CT) with intraoperative ultrasound (US) can augment anatomical visualization for the clinician. We propose an approach to rigidly align CT and US data of the lumbar spine. The approach involves an intensity-based volume registration step, followed by a surface segmentation and a point-based registration of the entire lumbar spine volume. A clinical feasibility study resulted in mean registration error of approximately 3 mm between CT and US data.

Nagpal, Simrin; Hacihaliloglu, Ilker; Ungi, Tamas; Rasoulian, Abtin; Osborn, Jill; Lessoway, Victoria A.; Rohling, Robert N.; Borschneck, Daniel P.; Abolmaesumi, Purang; Mousavi, Parvin

2014-03-01

306

EFFECT OF DIFFERENT LEVELS OF LOCALIZED MUSCLE FATIGUE ON KNEE POSITION SENSE  

Directory of Open Access Journals (Sweden)

Full Text Available There is little information available regarding how proprioceptive abilities decline as the amount of exertion increases during exercise. The purpose of this study was to determine the role of different levels of fatigue on knee joint position sense. A repeated measures design was used to examine changes in active joint reposition sense (AJRS prior to and following three levels of fatigue. Eighteen participants performed knee extension and flexion isokinetic exercise until torque output was 90%, 70%, or 50% of the peak hamstring torque for three consecutive repetitions. Active joint reposition sense at 15, 30, or 45 degrees was tested following the isokinetic exercise session. Following testing of the first independent measure, participants were given a 20 minute rest period. Testing procedures were repeated for two more exercise sessions following the other levels of fatigue. Testing of each AJRS test angle was conducted on three separate days with 48 hours between test days. Significant main effect for fatigue was indicated (p = 0.001. Pairwise comparisons indicated a significant difference between the pre-test and following 90% of peak hamstring torque (p = 0.02 and between the pre-test and following 50% of peak hamstring torque (p = 0.02. Fatigue has long been theorized to be a contributing factor in decreased proprioceptive acuity, and therefore a contributing factor to joint injury. The findings of the present study indicate that fatigue may have an effect on proprioception following mild and maximum fatigue.

William S. Gear

2011-12-01

307

Cartilaginous avulsion fracture of the tibial spine in a 5-year-old girl  

Energy Technology Data Exchange (ETDEWEB)

Fractures of the tibial spine usually occur in children aged 8 to 14 years. Usually, radiographs will demonstrate a tibial spine fracture, with the degree of displacement. Tibial spine fractures in younger children have not been reported in the previously published literature. We report a tibial spine fracture that occurred in 5-year-old girl. The cartilaginous avulsion fracture of the tibial spine was not revealed by radiographs because it was limited to the cartilaginous portion of the proximal tibia. (orig.)

Kim, Jung Ryul; Song, Ji Hun; Lee, Ju Hong [Chonbuk National University, Medical School, Department of Orthopaedic Surgery, Jeonju (Korea); Lee, Sang Yong [Chonbuk National University, Medical School, Department of Diagnostic Radiology, Jeonju (Korea); Yoo, Wan Hee [Chonbuk National University, Medical School, Department of Rheumatology, Jeonju (Korea)

2008-04-15

308

Anterior cervical spine fusion: struts, plugs, and plates  

Energy Technology Data Exchange (ETDEWEB)

Bone grafting in the cervical spine is an expanding and rapidly changing area. Its success depends on the presence of bone formation, bone incorporation, and ongoing adaptive remodeling to mechanical loads. The evaluation of anterior cervical spine grafts requires a basic understanding of bone graft physiology, its clinical applications, and its postoperative appearances. The roles of routine radiography, polydirectional tomography, computed tomography, and magnetic resonance imaging in the assessment and follow-up of the postoperatively grafted cervical spine will be discussed. The main focus on this paper is to review current surgical procedures utilized for stabilizing the cervica spine as well as to discuss the radiologist's role in the imaging of this region. (orig.)

Karasick, D. (Dept. of Radiology, Jefferson Medical Coll. and Thomas Jefferson Univ. Hospital, Philadelphia, PA (United States))

1993-02-01

309

Biomechanical analysis of Graf's dynamic spine stabilisation system ex vivo.  

Science.gov (United States)

The most frequent causes of chronic lumbar spine instability are of degenerative or traumatic origin. Numerous anterior and posterior stabilisation devices were developed for anatomical reconstruction of the spinal alignment and fusion of the spine to restore stability. Fusion of the spine results in increased load of adjacent segments with an increased risk of secondary degeneration which might result in instability or stenosis. To avoid the disadvantages of static devices, Graf developed a method of dynamic surgical treatment of spinal column instabilities, which is based on the principle of flexible stabilisation. This study is analysing the kinematics of discoligamentary intact motion segments compared with the experimentally destabilised human lumbar spine and the influence of Graf's stabilisation. According to our results, rotational instabilities cannot be satisfactorily stabilised by Graf's ligamentoplasty. With the present ex vivo study, it could be shown that it is possible to restore stability after discoligamentary lesion and after facetectomy using Graf's dynamic lordosis ligamentoplasty. PMID:11721585

Wild, A; Jaeger, M; Bushe, C; Raab, P; Krauspe, R

2001-10-01

310

Viscous dissipation in 3D spine reconnection solutions  

Science.gov (United States)

Aims: We consider the influence of viscous dissipation on "spine" reconnection solutions in coronal plasmas. It is known from 2D and 3D "fan" reconnection studies that viscous losses can be important. We extend these arguments to 3D "spine" reconnection solutions. Methods: Steady 3D spine reconnection models were constructed by time relaxation of the governing visco-resistive MHD equations. Scaling laws were derived that compare the relative importance of viscous and resistive damping. Results: It is shown that viscous dissipation in spine reconnection models can dominate resistive damping by many orders of magnitude. A similar conclusion, but with less severe implications, applies to current sheet "fan" solutions. These findings are not sensitive to whether classical or Braginskii viscosity is employed.

Craig, I. J. D.; Lopez, N.

2013-12-01

311

Asymmetric deformation structure of lava spine in Unzen Volcano, Japan  

Science.gov (United States)

Lava spine is commonly generated by effusive eruption of crystal-rich, dacitic-andesitic magmas. Especially, deformation rock on surface of lava spine has been related with processes of magma ascent, outgassing, and generation of volcanic earthquake (e.g., Cashman et al. 2008). To reveal the relationships and generation process of the spine, it is needed to understand a spatial distribution of the deformation rock. Here we show the spatial distribution of the deformation rock of lava spine in the Unzen volcano, Japan, to discuss the generation process of the spine. The lava spine in Unzen volcano is elongated in the E-W direction, showing a crest like shape with 150 long, 40 m wide and 50 m high. The lava spine is divided into following four parts: 1) Massive dacite part: Dense dacite with 30 m of maximum thickness, showing slickenside on the southern face; 2) Sheared dacite part: Flow band developed dacite with 1.0 m of maximum thickness; 3) Tuffisite part: Network of red colored vein develops in dacite with 0.5 m of maximum thickness; 4) Breccia part: Dacitic breccia with 10 m of maximum thickness. The Breccia part dominates in the northern part of the spine, and flops over Massive dacite part accross the Sheared dacite and Tuffisite parts. The slickenside on southern face of massive dacite demonstrates contact of solids. The slickenside breaks both of phenocryst and groundmass, demonstrating that the slickenside is formed after significant crystallization at the shallow conduit or on the ground surface. The lineation of the slickenside shows E-W direction with almost horizontal rake angle, which is consistent with the movement of the spine to an east before emplacement. Development of sub-vertical striation due to extrusion was observed on northern face of the spine (Hayashi, 1994). Therefore, we suggest that the spine just at extrusion consisted of Massive dacite, Sheared dacite, Tuffisite, Breccia, and Striation parts in the northern half of the spine. Such a variation of rock type is analogous to tectonic fault zone, suggesting that brittle failure of rigid magma due to contact with the conduit wall. Also similar variation is observed in the spine of Mt. St. Helens (Kendrick et al., 2012), which implies the existence of fault zone and brittle failure of magma are common features in the lava spine. The lava spine in Unzen volcano exhibits asymmetric deformation structure about direction of north and south. There is positive correlation between width and length in tectonic fault (Wells and Coppersmith, 1994). Therefore, development of fault zone (Sheared dacite, Tuffisite, and Breccia parts) in northern half may indicate that brittle failure starts at the deeper conduit for the northern half than the southern half of the spine. The asymmetry of magma ascent process is possible to result in asymmetries of outgassing path and location of volcanic earthquake in the conduit.

Miwa, T.; Okumura, S.; Matsushima, T.; Shimizu, H.

2013-12-01

312

Estimating Load on the Spine Using Spinal Shrinkage  

Directory of Open Access Journals (Sweden)

Full Text Available Changes in body height have been used as a measure of spine compression during loading. However, a gap exists in the literature as to the actual relationship that exists between spinal shrinkage and spine load as a result of load carrying or lifting. This study proposed a mathematical model for the relationship between spinal shrinkage and spinal load. The model was validated using some load carriers in a major market in Ibadan, Oyo State, Nigeria. The spinal shrinkages obtained from the study did not differ significantly from those calculated using the proposed model, thus suggesting that the model may be valid. The model established a relationship between load on the spine, spinal shrinkage, spine length and chest area.

Salami O. ISMAILA

2010-12-01

313

Staphylococcus aureus meningitis from osteomyelitis of the spine.  

Science.gov (United States)

Two cases of vertebral osteomyelitis presenting with secondary Staphylococcus aureus meningitis are described. In staphylococcal meningitis a search for a primary source should include the lower vertebral spine. PMID:2616438

Markus, H S; Allison, S P

1989-12-01

314

Anterior cervical spine fusion: struts, plugs, and plates  

International Nuclear Information System (INIS)

Bone grafting in the cervical spine is an expanding and rapidly changing area. Its success depends on the presence of bone formation, bone incorporation, and ongoing adaptive remodeling to mechanical loads. The evaluation of anterior cervical spine grafts requires a basic understanding of bone graft physiology, its clinical applications, and its postoperative appearances. The roles of routine radiography, polydirectional tomography, computed tomography, and magnetic resonance imaging in the assessment and follow-up of the postoperatively grafted cervical spine will be discussed. The main focus on this paper is to review current surgical procedures utilized for stabilizing the cervica spine as well as to discuss the radiologist's role in the imaging of this region. (orig.)

1993-02-01

315

[Primary amyloidosis of the spine presenting with acute paraplegia].  

Science.gov (United States)

Primary amylosis is rarely located in bone, exceptionally in the spine. The radiographic presentation is polymorphous. Magnetic resonance imaging is currently the best imaging technique. Spinal amyloidosis can exceptionally lead to cord compression requiring rapid surgical release. PMID:18774025

Ajlani, H; Zaouia, K; Chtourou, A; Elleuch, M; Bellil, S; Sellami, S

2008-09-01

316

[Traumatic fracture of the thoracic spine T1-T10].  

Science.gov (United States)

We describe the incidence, causes, management and prognosis of traumatic fractures of the thoracic spine from T1 to T10 in surgical cases of traumatic fractures of spine during the period from June 1994 to June 2003 studied retrospectively. The type of fracture was determined according to the Gertzbein classification, and the degree of stability using the Denis classification. The neurological picture at admission and 30 days after surgery was evaluated using the ASIA/IMSOP classification. Surgery was performed in patients with complete spinal cord injury (n=7) for the purpose of stabilization using the posterior approach. In cases without spinal cord injury or incomplete injury (n=12), the surgical procedure was performed aiming to decompress the nerve tissue, to correct the alignment of the spine and to stabilize the spine. PMID:15608977

Falavigna, Asdrubal; Righesso Neto, Orlando; Ferraz, Fernando Antonio Patriani; Boniatti, Márcio Manozzo

2004-12-01

317

Pediatric cervical spine trauma imaging: a practical approach  

Energy Technology Data Exchange (ETDEWEB)

Cervical spine trauma in children is rare and the diagnosis can be challenging due to anatomical and biomechanical differences as compared to adults. A variety of algorithms have been used in adults to accurately diagnose injuries, but have not been fully studied in pediatric patients. In this article we review suggested imaging protocols and the general characteristics, types of injuries, and measurements used to diagnose cervical spine injuries in children. (orig.)

Egloff, Alexia M.; Kadom, Nadja; Vezina, Gilbert; Bulas, Dorothy [Children' s National Medical Center, Department of Imaging and Radiology, Washington, DC (United States)

2009-05-15

318

Anterior endoscopically assisted transcervical reconstruction of the upper cervical spine  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Anterior decompression and/or reconstruction can be an effective method for the surgical treatment of ventral spinal cord compression in the upper cervical spine. Options for traditional surgical approaches include transoral, transnasal, and extraoral. The risk and complex anatomy with the aforementioned approaches induces surgeons to use the transcervical route to expose the upper cervical spine. A traditional transcervical approach, however, carries the disadvantages of a deep operative fie...

Wang, Bing; Lu?, Guohua; Deng, Youwen; Liu, Weidong; Li, Jing; Cheng, Ivan

2011-01-01

319

The spine of an SQG almost-sharp front  

International Nuclear Information System (INIS)

We study solutions of the surface quasi-geostrophic (SQG) equation which are locally constant outside a thin neighbourhood of a curve that evolves with time. To such an SQG solution we associate a distinguished curve (the 'spine'). If the above thin neighbourhood has thickness ?, then we prove that the spine satisfies its own evolution equation (equal to the sharp-front equation) modulo errors O(?2|log?|)

2012-02-01

320

Synovial osteochondromatosis of the cervical spine: A case report  

International Nuclear Information System (INIS)

Synovial osteochondromatosis is a rare, benign condition characterized by formation of cartilaginous nodules within the synovium. It rarely occurs at cervical spine, and only six cases have been previously reported in the English literature. We describe another case of synovial osteochondromatosis in the cervical spine in a 77-year-old man who presented with compressive myelopathy. Here we briefly review the literature and discuss the differential diagnosis based on CT and MR findings.

2014-05-01

 
 
 
 
321

Synovial osteochondromatosis of the cervical spine: A case report  

Energy Technology Data Exchange (ETDEWEB)

Synovial osteochondromatosis is a rare, benign condition characterized by formation of cartilaginous nodules within the synovium. It rarely occurs at cervical spine, and only six cases have been previously reported in the English literature. We describe another case of synovial osteochondromatosis in the cervical spine in a 77-year-old man who presented with compressive myelopathy. Here we briefly review the literature and discuss the differential diagnosis based on CT and MR findings.

Chee, Choong Guen; Lee, Joon Woo; Lee, Guen Young; Yeom, Jin S.; Choe, Ghee Young; Kang, Heung Sik [Seoul National University Bundang Hospital, Seongnam (Korea, Republic of)

2014-05-15

322

Thoracic trauma with injury of the thoracic spine  

International Nuclear Information System (INIS)

From a major series of surgically treated patients with fractures and fracture dislocations of the thoracic spine 4 cases are presented exhibiting different trauma mechanisms and presenting with a variety of associated acute and chronic intrathoracic lesions. Surgical stabilisation and treatment of additional intrathoracic injury (vascular, lymphatic duct, empyema, posttraumatic fibrothorax) nessecitated a transpleural approach, effective for the spine as well. Diagnostic radiology was restricted to minimal requirements due to urgency and/or difficulties of exposure. (orig.)

1987-01-01

323

Induction of dendritic spines by ?2-containing nicotinic receptors.  

Science.gov (United States)

Glutamatergic synapses are located mostly on dendritic spines in the adult nervous system. The spines serve as postsynaptic compartments, containing components that mediate and control the synaptic signal. Early in development, when glutamatergic synapses are initially forming, waves of excitatory activity pass through many parts of the nervous system and are driven in part by a class of heteropentameric ?2-containing nicotinic acetylcholine receptors (?2*-nAChRs). These ?2*-nAChRs are widely distributed and, when activated, can depolarize the membrane and elevate intracellular calcium levels in neurons. We show here that ?2*-nAChRs are essential for acquisition of normal numbers of dendritic spines during development. Mice constitutively lacking the ?2-nAChR gene have fewer dendritic spines than do age-matched wild-type mice at all times examined. Activation of ?2*-nAChRs by nicotine either in vivo or in organotypic slice culture quickly elevates the number of spines. RNA interference studies both in vivo and in organotypic culture demonstrate that the ?2*-nAChRs act in a cell-autonomous manner to increase the number of spines. The increase depends on intracellular calcium and activation of calcium, calmodulin-dependent protein kinase II. Absence of ?2*-nAChRs in vivo causes a disproportionate number of glutamatergic synapses to be localized on dendritic shafts, rather than on spines as occurs in wild type. This shift in synapse location is found both in the hippocampus and cortex, indicating the breadth of the effect. Because spine synapses differ from shaft synapses in their signaling capabilities, the shift observed is likely to have significant consequences for network function. PMID:22699919

Lozada, Adrian F; Wang, Xulong; Gounko, Natalia V; Massey, Kerri A; Duan, Jingjing; Liu, Zhaoping; Berg, Darwin K

2012-06-13

324

Spine Expansion and Stabilization Associated with Long-term Potentiation  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Stable expression of long-term synaptic plasticity is critical for the developmental refinement of neural circuits and for some forms of learning and memory. Although structural remodeling of dendritic spines is associated with the stable expression of long term potentiation (LTP), the relationship between structural and physiological plasticity remains unclear. To define whether these two processes are related or distinct, we simultaneously monitored EPSPs and dendritic spines, using combine...

Yang, Yunlei; Wang, Xiao-bin; Frerking, Matthew; Zhou, Qiang

2008-01-01

325

Spine stability: the six blind men and the elephant  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Stability is one of the most fundamental concepts to characterize and evaluate any system. This term is often ambiguously used in spinal biomechanics. Confusion arises when the static analyses of stability are used to study dynamic systems such as the spine. Therefore, the purpose of this paper is to establish a common ground of understanding, using standard, well-defined terms to frame future discussions regarding spine dynamics, stability, and injury. A qualitative definition of stability, ...

2007-01-01

326

Thoracic trauma with injury of the thoracic spine  

Energy Technology Data Exchange (ETDEWEB)

From a major series of surgically treated patients with fractures and fracture dislocations of the thoracic spine 4 cases are presented exhibiting different trauma mechanisms and presenting with a variety of associated acute and chronic intrathoracic lesions. Surgical stabilisation and treatment of additional intrathoracic injury (vascular, lymphatic duct, empyema, posttraumatic fibrothorax) nessecitated a transpleural approach, effective for the spine as well. Diagnostic radiology was restricted to minimal requirements due to urgency and/or difficulties of exposure.

Hasse, J.; Morscher, E.

1987-09-01

327

Stability of the human spine in neutral postures  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The present study aimed to identify some of the mechanisms affecting spinal compressive load-bearing capacity in neutral postures. Two spinal geometries were employed in the evaluation of the stabilizing mechanisms of the spine in standing neutral postures. Large-displacement finite-element models were used for parametric studies of the effect of load distribution, initial geometry, and pelvic rotation on the compression stability of the spine. The role of muscles in stabilization of the spin...

Kiefer, A.; Parnianpour, M.; Shirazi-adl, A.

1997-01-01

328

Pediatric cervical spine trauma imaging: a practical approach  

International Nuclear Information System (INIS)

Cervical spine trauma in children is rare and the diagnosis can be challenging due to anatomical and biomechanical differences as compared to adults. A variety of algorithms have been used in adults to accurately diagnose injuries, but have not been fully studied in pediatric patients. In this article we review suggested imaging protocols and the general characteristics, types of injuries, and measurements used to diagnose cervical spine injuries in children. (orig.)

2009-05-01

329

Primary Dural Repair in Minimally Invasive Spine Surgery  

Digital Repository Infrastructure Vision for European Research (DRIVER)

We describe an effective surgical technique in primary repair of the spinal dura during minimally invasive spine surgery (MISS). Objective. Minimally invasive spine surgery includes the treatment of intradural lesions, and proper closure of the dura is necessary. However, primary dural closure can be difficult due to the restricted space of MIS retractors and the availability of appropriate surgical instrumentation. Methods. We describe the use of a needle already used in the pediatric neuros...

Haque, Raqeeb M.; Hashmi, Sohaib Z.; Ahmed, Yousef; Uddin, Omar; Ogden, Alfred T.; Fessler, Richard

2013-01-01

330

Chondrosarcoma of the spine: A rare case with unusual presentation  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Abstract Chondrosarcoma is the third most common primary malignancy of bone, affecting primarily the pelvic and shoulder girdles and being extremely rare in the spine. Herein, we present a case of a 65-year-old woman with a rare chondrosarcoma of the spine, who presented with clinical symptoms from the lung metastasis. The neoplasm was grade II and exhibited overexpression of the p53 tumor suppressor protein. The latter has been associated with a high propensity for distant metastas...

Panelos John; Voulgaris Spyridon; Michos Evangelos; Doukas Michael; Charalabopoulos Konstantinos; Batistatou Anna

2006-01-01

331

Chondrosarcoma of the spine: A rare case with unusual presentation  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Chondrosarcoma is the third most common primary malignancy of bone, affecting primarily the pelvic and shoulder girdles and being extremely rare in the spine. Herein, we present a case of a 65-year-old woman with a rare chondrosarcoma of the spine, who presented with clinical symptoms from the lung metastasis. The neoplasm was grade II and exhibited overexpression of the p53 tumor suppressor protein. The latter has been associated with a high propensity for distant metastases.

Charalabopoulos Konstantinos

2006-10-01

332

Complications of transpedicular screw fixation in the cervical spine  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Today, posterior stabilization of the cervical spine is most frequently performed by lateral mass screws or spinous process wiring. These techniques do not always provide sufficient stability, and anterior fusion procedures are added secondarily. Recently, transpedicular screw fixation of the cervical spine has been introduced to provide a one-stage stable posterior fixation. The aim of the present prospective study is to examine if cervical pedicle screw fixation can be done by low risk and ...

Kast, E.; Mohr, K.; Richter, H. -p; Bo?rm, W.

2006-01-01

333

Aneurysmal bone cyst of thoracic spine mimicking spinal tuberculosis  

Digital Repository Infrastructure Vision for European Research (DRIVER)

A 22-year-old female presented to our services with back pain and paraparesis for 11 months. She was earlier diagnosed with tuberculosis of spine, and antitubercular chemotherapy was started. However her condition had worsened. Plain and contrast-enhanced computed tomography scans of the thorax and magnetic resonance imaging of the thoracic spine showed heterogenous, lytic, expansile lesion involving third thoracic vertebra with epidural extension and large bilateral paraspinal and mediastina...

Mathur, Shobhit; Aswani, Yashant; Sankhe, Shilpa S.; Hira, Priya R.

2011-01-01

334

Automated curved planar reformation of 3D spine images  

International Nuclear Information System (INIS)

Traditional techniques for visualizing anatomical structures are based on planar cross-sections from volume images, such as images obtained by computed tomography (CT) or magnetic resonance imaging (MRI). However, planar cross-sections taken in the coordinate system of the 3D image often do not provide sufficient or qualitative enough diagnostic information, because planar cross-sections cannot follow curved anatomical structures (e.g. arteries, colon, spine, etc). Therefore, not all of the important details can be shown simultaneously in any planar cross-section. To overcome this problem, reformatted images in the coordinate system of the inspected structure must be created. This operation is usually referred to as curved planar reformation (CPR). In this paper we propose an automated method for CPR of 3D spine images, which is based on the image transformation from the standard image-based to a novel spine-based coordinate system. The axes of the proposed spine-based coordinate system are determined on the curve that represents the vertebral column, and the rotation of the vertebrae around the spine curve, both of which are described by polynomial models. The optimal polynomial parameters are obtained in an image analysis based optimization framework. The proposed method was qualitatively and quantitatively evaluated on five CT spine images. The method performed well on both normal and pathological cases and was consistent with manually obtained ground truth data. The proposed spine-based CPR benefits from reduced structural complexity in favour of improved feature perception of the spine. The reformatted images are diagnostically valuable and enable easier navigation, manipulation and orientation in 3D space. Moreover, reformatted images may prove useful for segmentation and other image analysis tasks

2005-10-07

335

Automated curved planar reformation of 3D spine images  

Energy Technology Data Exchange (ETDEWEB)

Traditional techniques for visualizing anatomical structures are based on planar cross-sections from volume images, such as images obtained by computed tomography (CT) or magnetic resonance imaging (MRI). However, planar cross-sections taken in the coordinate system of the 3D image often do not provide sufficient or qualitative enough diagnostic information, because planar cross-sections cannot follow curved anatomical structures (e.g. arteries, colon, spine, etc). Therefore, not all of the important details can be shown simultaneously in any planar cross-section. To overcome this problem, reformatted images in the coordinate system of the inspected structure must be created. This operation is usually referred to as curved planar reformation (CPR). In this paper we propose an automated method for CPR of 3D spine images, which is based on the image transformation from the standard image-based to a novel spine-based coordinate system. The axes of the proposed spine-based coordinate system are determined on the curve that represents the vertebral column, and the rotation of the vertebrae around the spine curve, both of which are described by polynomial models. The optimal polynomial parameters are obtained in an image analysis based optimization framework. The proposed method was qualitatively and quantitatively evaluated on five CT spine images. The method performed well on both normal and pathological cases and was consistent with manually obtained ground truth data. The proposed spine-based CPR benefits from reduced structural complexity in favour of improved feature perception of the spine. The reformatted images are diagnostically valuable and enable easier navigation, manipulation and orientation in 3D space. Moreover, reformatted images may prove useful for segmentation and other image analysis tasks.

Vrtovec, Tomaz; Likar, Bostjan; Pernus, Franjo [University of Ljubljana, Faculty of Electrical Engineering, Trzaska 25, SI-1000 Ljubljana (Slovenia)

2005-10-07

336

Maintenance of graft compression in the adult cervical spine  

Digital Repository Infrastructure Vision for European Research (DRIVER)

It is generally advised that the graft inserted in adult cervical spine should be pre-loaded with a compressive force or that the screws are inserted in a divergent orientation, in order to maximise compression and the chance of graft incorporation (Truumees et al. in Spine 28:1097–1102, 2003). However, there is little evidence that a compressive force is maintained once the force applicator has been removed, or that the divergent screws enhance compression. This study compared the maintena...

2006-01-01

337

HORIZON SENSING  

Energy Technology Data Exchange (ETDEWEB)

Real-time horizon sensing (HS) on continuous mining (CM) machines is becoming an industry tool. Installation and testing of production-grade HS systems has been ongoing this quarter at Oxbow Mining Company, Monterey Coal Company (EXXON), FMC Trona, Twentymile Coal Company (RAG America), and SASOL Coal. Detailed monitoring of system function, user experience, and mining benefits is ongoing. All horizon sensor components have finished MSHA (United States) and IEC (International) certification.

Larry G. Stolarczyk, Sc.D.

2002-07-31

338

Villonodular synovitis (PVNS) of the spine  

International Nuclear Information System (INIS)

To describe the imaging features of spinal pigmented villonodular synovitis (PVNS). We retrospectively reviewed 15 cases of pathologically proven spinal PVNS. Patient demographics and clinical presentation were reviewed. Radiologic studies were evaluated by consensus of two musculoskeletal radiologists for spinal location, spinal segments affected, lesion center, detection of facet origin and intrinsic characteristics on radiography (n =11), myelography (n =7), CT (n =6) and MR imaging (n =6). Women (64%) were more commonly affected than men (36%) with an average age of 28 years. Clinical symptoms were pain (45%), neurologic (9%) or both (36%). Lesions most frequently affected the cervical spine (53%) followed by the thoracic (27%) and lumbar regions (20%). The majority of lesions (93%) were centered in the posterior elements with frequent involvement of the pedicle (67%), neural foramina (73%), lamina (67%) and facets (93%). No lesions showed calcification. Determination of a facet origin by imaging was dependent on imaging modality and lesion size. A facet origin could be determined in 45% of cases by radiography vs 67% of patients by CT (n=6) and MR (n=6). Large lesions (greater than 3 cm in at least one dimension) obscured the facet origin in all cases with CT and/or MR imaging (44%,n=4). Small lesions (less than 3 cm in any dimension) demonstrated an obvious facet origin in all cases by CT and/or MR imaging (56%,n=5). Low-to-intermediate signal intensity was seen in all cases on T2-weighted MR images resulting from hemosiderin deposition with ''blooming effect'' in one case with gradient echo MR images. PVNS of the spine is rare. Large lesions obscure the facet origin and simulate an aggressive intraosseous neoplasm. Patient age, a solitary noncystic lesion centered in the posterior elements, lack of mineralization and low-to-intermediate signal intensity on all MR pulse sequences may suggest the diagnosis in these cases. Small lesions demonstrate a facet origin on CT or MR imaging. This limits differential considerations to synovial-based lesions and additional features of a solitary focus, lack of underlying disease or systemic arthropathy, no calcification as well as low-to-intermediate signal intensity on all MR images should allow spinal PVNS to be suggested as the likely diagnosis. (orig.)

2005-04-01

339

Villonodular synovitis (PVNS) of the spine  

Energy Technology Data Exchange (ETDEWEB)

To describe the imaging features of spinal pigmented villonodular synovitis (PVNS). We retrospectively reviewed 15 cases of pathologically proven spinal PVNS. Patient demographics and clinical presentation were reviewed. Radiologic studies were evaluated by consensus of two musculoskeletal radiologists for spinal location, spinal segments affected, lesion center, detection of facet origin and intrinsic characteristics on radiography (n =11), myelography (n =7), CT (n =6) and MR imaging (n =6). Women (64%) were more commonly affected than men (36%) with an average age of 28 years. Clinical symptoms were pain (45%), neurologic (9%) or both (36%). Lesions most frequently affected the cervical spine (53%) followed by the thoracic (27%) and lumbar regions (20%). The majority of lesions (93%) were centered in the posterior elements with frequent involvement of the pedicle (67%), neural foramina (73%), lamina (67%) and facets (93%). No lesions showed calcification. Determination of a facet origin by imaging was dependent on imaging modality and lesion size. A facet origin could be determined in 45% of cases by radiography vs 67% of patients by CT (n=6) and MR (n=6). Large lesions (greater than 3 cm in at least one dimension) obscured the facet origin in all cases with CT and/or MR imaging (44%,n=4). Small lesions (less than 3 cm in any dimension) demonstrated an obvious facet origin in all cases by CT and/or MR imaging (56%,n=5). Low-to-intermediate signal intensity was seen in all cases on T2-weighted MR images resulting from hemosiderin deposition with ''blooming effect'' in one case with gradient echo MR images. PVNS of the spine is rare. Large lesions obscure the facet origin and simulate an aggressive intraosseous neoplasm. Patient age, a solitary noncystic lesion centered in the posterior elements, lack of mineralization and low-to-intermediate signal intensity on all MR pulse sequences may suggest the diagnosis in these cases. Small lesions demonstrate a facet origin on CT or MR imaging. This limits differential considerations to synovial-based lesions and additional features of a solitary focus, lack of underlying disease or systemic arthropathy, no calcification as well as low-to-intermediate signal intensity on all MR images should allow spinal PVNS to be suggested as the likely diagnosis. (orig.)

Motamedi, Kambiz [Armed Forces Institute of Pathology, Department of Radiologic Pathology, Washington, DC (United States); David Geffen School of Medicine at UCLA, Department of Radiology (Section of Musculoskeletal Radiology), 200 UCLA Medical Plaza, Suite 165-59, Los Angeles, CA (United States); Murphey, Mark D. [Armed Forces Institute of Pathology, Department of Radiologic Pathology, Washington, DC (United States); Uniformed Services University of Health Sciences, Department of Radiology and Nuclear Medicine, Bethesda, MD (United States); University of Maryland School of Medicine, Department of Radiology, Baltimore, MD (United States); Fetsch, John F.; Furlong, Mary A. [Armed Forces Institute of Pathology, Department of Soft Tissue Pathology, Washington, DC (United States); Vinh, Tinhoa N.; Sweet, Donald E. [Armed Forces Institute of Pathology, Department of Orthopedic Pathology, Washington, DC (United States); Laskin, William B. [Northwestern Memorial Hospital, Department of Surgical Pathology, Chicago, IL (United States)

2005-04-01

340

History of spine surgery in older obese patients  

Directory of Open Access Journals (Sweden)

Full Text Available Goal: To study the interaction of obesity and age in patients with multiple spine surgeries. Methods: Data on the body mass index (BMI of 956 patients were collected and classified into four groups: non-obese (BMI <30 kg/m2, obese-class I (BMI ?30 kg/m2, obese-class II (BMI ?35 kg/m2 and obese-class III (BMI ?40 kg/m2. Patients' age was categorized into the following age groups: ?40, 41–65 and ?66. T-test and Chi-square test were applied using SPSS v16. Results: In lumbar patients aged ?66 years with previous spine surgery, the average number of previous spine surgeries significantly increased with increasing obesity from 1.4 in nonobese patients to 1.7, 2.5 and 3.5 in obese class I, II and III patients.In lumbar decompression and fusion patients aged ?66 years with previous spine surgery, the average number of previous spine surgeries signifi-cantly increased with increasing obesity from 1.7 in nonobese patients to 1.6, 2.0 and 3.5 in obese class I, II and III patients. A similar trend was noted in lumbar microdiskectomy patients aged ?66 years but it was statistically nonsignificant due probably to small numbers. Conclusion: Obesity is associated with an increased number of previous spine surgeries in patients over 65 years of age undergoing lumbar surgery.

Zaytseva, Nadezhda

2011-01-01

 
 
 
 
341

Rheumatoid arthritis: Radiological changes in the cervical spine  

International Nuclear Information System (INIS)

Objective was to describe the radiographic cervical spine changes in rheumatoid arthritis patients.Forty-nine patients (37 females and 12 males ) diagnosed with rheumatoid arthritis at King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia between June 1998 and December 2000, were studied for their radiographic cervical spine changes . Their mean age at disease onset was 41.4+ 13.4 years (range of 18-73)and mean duration of disease was 9.1+-6.28 years (range of 2-34). Their demographic data including rheumatoid factor status was obtained. Standard conventional radiographs cervical spine were obtained to study the cervical spine changes. Cervical radiographic changes were found in 34 patients (27 females and 7 males) 10 had subluxation (7 with atlanto-axial subluxation,2 with sub-axial subluxation,and one with lateral subluxation ). No vertical impaction was seen. Erosion of odontoid process was seen in one patient .All were rheumatoid seropositive Cervical spine changes in patients with rheumatoid arthritis are common, in particular subluxation in the upper cervical spine. Our study showed somewhat lesser prevalence of these changes. These were clinically correlated with disease duration, female sex, and rheumatoid factor, but were not clinically significant. (author)

1998-06-00

342

Instrumentation of the paediatric cervical spine  

Scientific Electronic Library Online (English)

Full Text Available SciELO South Africa | Language: English Abstract in english BACKGROUND: Paediatric cervical fusion surgery is challenging. Traditional techniques such as external stabilisation, onlay fusions and wiring techniques resulted in unsatisfactory outcomes due to inferior biomechanical stability. METHODS: A retrospective review was performed of paediatric patients [...] who underwent instrumented cervical fusion surgery under 16 years of age. Fusion rates, blood loss, levels fused, theatre time, technique and complications were assessed. RESULTS: An average of 2.5 levels was fused, with an estimated blood loss of 428 ml and surgical duration of 159 min. Anterior procedures had an average of one level fused with blood loss of 117 ml and surgical duration of 98 min. Posterior procedures had an average number of 1.9 levels fused, blood loss of 306 ml and surgical time of 131 min. Combined procedures had an average of 5.5 levels fused, blood loss 810 ml and surgical duration of 241 min. Four surgery-related complications were encountered. These consisted of dural leaks and wound sepsis which were all treated effectively. All patients achieved radiological fusion. CONCLUSION: The use of modern segmental spinal instrumentation in the paediatric cervical spine is a viable option. Although the study sample was small we are able to demonstrate that no major surgical complications were encountered due to the use of adult cervical spinal instrumentation techniques in the paediatric group.

RN, Dunn; AH, Botha.

343

Repair of the spondylolysis in lumbar spine  

International Nuclear Information System (INIS)

The objective is to present the surgical experience in the repair of the spondylolysis in lumbar spine. Background: Spodylolysis is an important cause of low back pain in young adults and is responsible for high grade of incapacity. Classically, patients with surgical indications with Spondylolysis have been treated with vertebral arthrodesis arthrodesis, with the following functional lost of the intervened segment and biomechanical overload of the upper contiguous segment. There are not previous reports about repairing of lysis in national literature and international references in this technique are scarce. Materials and methods: Eight patients within 2002-2004 were operated, a direct repairing of the lyses by in situ, fusion and interfragmental osteosynthesis with AO 3.5 mm titanium cortical screws with autogenous bone grafts was achieved. The casuistic was analyzed depending on clinical presentation, consolidation, mobility and vitality of the disc in imaginology studies. Results: During the follow-up a firm fusion in all cases, mobility and vitality preservation of the L5-S1 intervertebral disc was detected. There was neither infection nor neurological deficit. Recommendations: Repairing of spondylolysis in lumbar column, in young symptomatic patients without or with mild lystesis (grade I) and without associated disc damage, is a safe surgical technique

2005-09-01

344

Adjacent segment disease after cervical spine fusion.  

Science.gov (United States)

Anterior cervical diskectomy and fusion is one of the most common cervical spine procedures. Although it is usually successful in relieving the symptoms of radiculopathy and myelopathy, the subsequent development of clinically significant disk disease at levels adjacent to the fusion is a matter of concern. Adjacent segment cervical disease occurs in approximately 3% of patients; the incidence is expected to increase to more than 25% of patients within the first 10 years after the index fusion procedure. The disease is well described in the literature, and significant basic science and clinical research has been conducted. Nonetheless, the cause of the disease is a matter of debate. A combination of factors probably contributes to its development, including the increased biomechanical stress placed on the disk space adjacent to a fusion and the natural history of cervical spondylosis in patients known to have such pathology. Clinical and biomechanical data are available to support each of these claims. Symptomatic disk disease adjacent to a cervical fusion is a significant clinical problem, and, therefore, motion-sparing technology has been developed to reduce its incidence. Two cervical disk replacement systems are currently approved by the US Food and Drug Administration for the treatment of symptomatic cervical spondylosis. PMID:19385583

Rihn, Jeffrey A; Lawrence, James; Gates, Charley; Harris, Eric; Hilibrand, Alan S

2009-01-01

345

Conjoined nerve root of the lumbar spine  

International Nuclear Information System (INIS)

There have been a number of reports on lumbosacral nerve root anomalies. Among the most common of these anomalies is the conjoined nerve root. However, it is difficult to diagnose this condition preoperatively. We review the records of 142 patients who underwent microendoscopic discectomy (MED) for herniation of the lumbar disc. All patients had undergone magnetic resonance imaging (MRI) of the lumbar spine before surgery. For most patients, only sagittal and axial images were obtained; coronal images were obtained in only a minority of the patients. Postoperative coronal images were obtained in patients with conjoined nerve roots. A diagnosis of conjoined nerve roots was made intraoperatively in 4 patients; this diagnosis had not been possible preoperatively. After surgery, new coronal images were obtained for the 4 patients with conjoined nerve roots; however, there was no evidence of the condition on the new images. The surgical procedure employed was endoscopic decompression and herniotomy. The results were favorable, even though pediculotomy was not performed. It is difficult to diagnose nerve root anomalies preoperatively. However, the possibility of nerve root anomalies should always be considered during surgery to ensure a safe procedure, without intraoperative occurrence of nerve root injury. (author)

2009-07-01

346

CT in the evaluation of spine trauma  

International Nuclear Information System (INIS)

The introduction of computed tomography has had a major impact on the diagnostic approach to the spine trauma patient. The high resolution of new generation CT equipment allows definitive evaluation of bony disruption within the spinal column. Multiplanar image reformation permits three-dimensional assessment of the injury, optimizes patient comfort and safety, and minimizes the time necessary for the diagnosis. Water-soluble contrast can be used to expand greatly the utility of computed tomography. Utilizing the cervical puncture approach, small doses of contrast can be instilled in the subarachnoid space with the patient supine and semi-upright on a tiltable gurney. Such contrast enhancement can provide additional information in acutely traumatized patients with neurologic deficits. Dynamic sequence scanning with automatic table incrementation permits thorough evaluation of severe spinal trauma in less than 15 minutes following patient transfer onto the scanning couch. Because of its many advantages, CT has become the diagnostic procedure of choice in the evaluation of spinal injury when plain films and/or clinical data indicate the need for further diagnostic measures

1986-01-01

347

HORIZON SENSING  

Energy Technology Data Exchange (ETDEWEB)

With the aid of a DOE grant (No. DE-FC26-01NT41050), Stolar Research Corporation (Stolar) developed the Horizon Sensor (HS) to distinguish between the different layers of a coal seam. Mounted on mining machine cutter drums, HS units can detect or sense the horizon between the coal seam and the roof and floor rock, providing the opportunity to accurately mine the section of the seam most desired. HS also enables accurate cutting of minimum height if that is the operator's objective. Often when cutting is done out-of-seam, the head-positioning function facilitates a fixed mining height to minimize dilution. With this technology, miners can still be at a remote location, yet cut only the clean coal, resulting in a much more efficient overall process. The objectives of this project were to demonstrate the feasibility of horizon sensing on mining machines and demonstrate that Horizon Sensing can allow coal to be cut cleaner and more efficiently. Stolar's primary goal was to develop the Horizon Sensor (HS) into an enabling technology for full or partial automation or ''agile mining''. This technical innovation (R&D 100 Award Winner) is quickly demonstrating improvements in productivity and miner safety at several prominent coal mines in the United States. In addition, the HS system can enable the cutting of cleaner coal. Stolar has driven the HS program on the philosophy that cutting cleaner coal means burning cleaner coal. The sensor, located inches from the cutting bits, is based upon the physics principles of a Resonant Microstrip Patch Antenna (RMPA). When it is in proximity of the rock-coal interface, the RMPA impedance varies depending on the thickness of uncut coal. The impedance is measured by the computer-controlled electronics and then sent by radio waves to the mining machine. The worker at the machine can read the data via a Graphical User Interface, displaying a color-coded image of the coal being cut, and direct the machine appropriately. The Horizon Sensor program began development in 1998 and experienced three major design phases. The final version, termed HS-3, was commissioned in 2000 with the assistance of the DOE-Mining Industry of the Future program, commercialized in 2002, and has been used 14 times in 12 different mines within the United States. The Horizon Sensor has applications in both underground and surface mining operations. This technology is primarily used in the coal industry, but is also used to mine trona and potash. All horizon sensor components have Mine Safety and Health Administration (MSHA) (United States) and IEC (International) certification. Horizon Sensing saves energy by maximizing cutting efficiency, cutting only desired material. This desired material is cleaner fuel, therefore reducing pollutants to the atmosphere when burned and burning more efficiently. Extracting only desired material increases productivity by reducing or eliminating the cleaning step after extraction. Additionally, this technology allows for deeper mining, resulting in more material gained from one location. The remote sensing tool allows workers to operate the machinery away from the hazards of cutting coal, including noise, breathing dust and gases, and coal and rock splintering and outbursts. The HS program has primarily revolved around the development of the technology. However, the end goal of the program has always been the commercialization of the technology and only within the last 2 years of the program has this goal been realized. Real-time horizon sensing on mining machines is becoming an industry tool. Detailed monitoring of system function, user experience, and mining benefits is ongoing.

Larry G. Stolarczyk

2003-03-18

348

Minimally invasive spine surgery in the treatment of thoracolumbar and lumbar spine trauma.  

Science.gov (United States)

Thoracolumbar and lumbar trauma account for the majority of traumatic spinal injuries. The mainstay of current treatments is still nonoperative therapy with bracing. Classic treatment algorithms reserved absolute surgical intervention for spinal trauma patients with neurological compromise or instability. Relative indications included incapacitating pain and obesity/body habitus making brace therapy ineffective. In the past decade, minimally invasive surgical (MIS) techniques for spine surgery have been increasingly used for degenerative conditions. These same minimally invasive techniques have seen increased use in trauma patients. The goal of minimally invasive surgery is to decrease surgical morbidity through decreased soft-tissue dissection while providing the same structural stability afforded by classic open techniques. These minimally invasive techniques involve percutaneous posterior pedicle fixation, vertebral body augmentation, and utilization of endoscopic and thoracoscopic techniques. While MIS techniques are somewhat in their infancy, an increasing number of studies are reporting good clinical and radiographic outcomes with these MIS techniques. However, the literature is still lacking high-quality evidence comparing these newer techniques to classic open treatments. This article reviews the relevant literature regarding minimally invasive spine surgery in the treatment of thoracolumbar and lumbar trauma. PMID:24981899

Koreckij, Theodore; Park, Daniel K; Fischgrund, Jeffrey

2014-07-01

349

Helical tomotherapy for spine oligometastases from gastrointestinal malignancies  

International Nuclear Information System (INIS)

This study evaluated the treatment effectiveness and proper radiation dose of helical tomotherapy (HT) in spine oligometastases from gastrointestinal cancers. From 2006 to 2010, 20 gastrointestinal cancer patients were treated with HT for spine oligometastases (31 spine lesions). The gross tumor volume (GTV) was the tumor evident from magnetic resonance imaging images fused with simulation computed tomography images. Clinical target volume (CTV) encompassed involved vertebral bodies or dorsal elements. We assumed that the planning target volume was equal to the CTV. We assessed local control rate after HT for 31 spine metastases. Pain response was scored by using a numeric pain intensity scale (NPIS, from 0 to 10). Spine metastatic lesions were treated with median dose of 40 Gy (range, 24 to 51 Gy) and median 5 Gy per fraction (range, 2.5 to 8 Gy) to GTV with median 8 fractions (range, 3 to 20 fraction). Median biologically equivalent dose (BED, ?/? = 10 Gy) was 52 Gy10 (range, 37.5 to 76.8 Gy10) to GTV. Six month local control rate for spine metastasis was 90.3%. Overall infield failure rate was 15% and outfield failure rate was 75%. Most patients showed pain relief after HT (93.8%). Median local recurrence free survival was 3 months. BED over 57 Gy10 and oligometastases were identified as prognostic factors associated with improved local progression free survival (p = 0.012, p = 0.041). HT was capable of delivering higher BED to metastatic lesions in close proximity of the spinal cord. Spine metastases from gastrointestinal tumors were sensitive to high dose radiation, and BED (?/? = 10 Gy) higher than 57 Gy10 could improve local control.

2011-12-01

350

Comparison of Three Prehospital Cervical Spine Protocols for Missed Injuries  

Science.gov (United States)

Introduction We wanted to compare 3 existing emergency medical services (EMS) immobilization protocols: the Prehospital Trauma Life Support (PHTLS, mechanism-based); the Domeier protocol (parallels the National Emergency X-Radiography Utilization Study [NEXUS] criteria); and the Hankins’ criteria (immobilization for patients 65 years, those with altered consciousness, focal neurologic deficit, distracting injury, or midline or paraspinal tenderness).To determine the proportion of patients who would require cervical immobilization per protocol and the number of missed cervical spine injuries, had each protocol been followed with 100% compliance. Methods This was a cross-sectional study of patients ?18 years transported by EMS post-traumatic mechanism to an inner city emergency department. Demographic and clinical/historical data obtained by physicians were recorded prior to radiologic imaging. Medical record review ascertained cervical spine injuries. Both physicians and EMS were blinded to the objective of the study. Results Of 498 participants, 58% were male and mean age was 48 years. The following participants would have required cervical spine immobilization based on the respective protocol: PHTLS, 95.4% (95% CI: 93.1–96.9%); Domeier, 68.7% (95% CI: 64.5–72.6%); Hankins, 81.5% (95% CI: 77.9–84.7%). There were 18 cervical spine injuries: 12 vertebral fractures, 2 subluxations/dislocations and 4 spinal cord injuries. Compliance with each of the 3 protocols would have led to appropriate cervical spine immobilization of all injured patients. In practice, 2 injuries were missed when the PHTLS criteria were mis-applied. Conclusion Although physician-determined presence of cervical spine immobilization criteria cannot be generalized to the findings obtained by EMS personnel, our findings suggest that the mechanism-based PHTLS criteria may result in unnecessary cervical spine immobilization without apparent benefit to injured patients. PHTLS criteria may also be more difficult to implement due to the subjective interpretation of the severity of the mechanism, leading to non-compliance and missed injury.

Hong, Rick; Meenan, Molly; Prince, Erin; Murphy, Ronald; Tambussi, Caitlin; Rohrbach, Rick; Baumann, Brigitte M

2014-01-01

351

Helical tomotherapy for spine oligometastases from gastrointestinal malignancies  

Energy Technology Data Exchange (ETDEWEB)

This study evaluated the treatment effectiveness and proper radiation dose of helical tomotherapy (HT) in spine oligometastases from gastrointestinal cancers. From 2006 to 2010, 20 gastrointestinal cancer patients were treated with HT for spine oligometastases (31 spine lesions). The gross tumor volume (GTV) was the tumor evident from magnetic resonance imaging images fused with simulation computed tomography images. Clinical target volume (CTV) encompassed involved vertebral bodies or dorsal elements. We assumed that the planning target volume was equal to the CTV. We assessed local control rate after HT for 31 spine metastases. Pain response was scored by using a numeric pain intensity scale (NPIS, from 0 to 10). Spine metastatic lesions were treated with median dose of 40 Gy (range, 24 to 51 Gy) and median 5 Gy per fraction (range, 2.5 to 8 Gy) to GTV with median 8 fractions (range, 3 to 20 fraction). Median biologically equivalent dose (BED, {alpha}/{beta} = 10 Gy) was 52 Gy10 (range, 37.5 to 76.8 Gy10) to GTV. Six month local control rate for spine metastasis was 90.3%. Overall infield failure rate was 15% and outfield failure rate was 75%. Most patients showed pain relief after HT (93.8%). Median local recurrence free survival was 3 months. BED over 57 Gy10 and oligometastases were identified as prognostic factors associated with improved local progression free survival (p = 0.012, p = 0.041). HT was capable of delivering higher BED to metastatic lesions in close proximity of the spinal cord. Spine metastases from gastrointestinal tumors were sensitive to high dose radiation, and BED ({alpha}/{beta} = 10 Gy) higher than 57 Gy10 could improve local control.

Choi, Yun Seon; Kim, Jun Won; Lee, Ik Jae; Han, Hee Ji; Baek, Jong Geal; Seong, Jin Sil [Yonsei University Health System, Seoul (Korea, Republic of)

2011-12-15

352

The spatial repositioning of adipogenesis genes is correlated with their expression status in a porcine mesenchymal stem cell adipogenesis model system.  

Science.gov (United States)

Alterations in the nuclear positioning of chromosomes and specific genes during differentiation and development have suggested strongly the existence of a relationship between non-random organization of the genome and its function. In this study, we have examined the genome organization in interphase nuclei during adipogenesis, using the pig as a model organism. We hypothesized that changes in the gene expression profile and chromatin remodeling which occur during cellular differentiation would elicit repositioning of whole chromosomes, moving specific genes on them to different regions of the nucleus. We established an in vitro adipogenesis differentiation system using mesenchymal stem cells, derived from porcine bone marrow. The nuclear position of seven adipogenesis genes (PPARG, SREBF1, FABP4, CEBPA, CEBPB, CREB, and GATA2), two control genes (SOX9 and MYL1), and six chromosomes carrying these gene loci (SSC4, SSC6, SSC12, SSC13, SSC15, and SSC17) was determined. We found that during adipogenesis, using the in vitro stem cell model system, in contrast to our original hypothesis, the nuclear position of genes involved in adipogenesis was altered radically with the up-regulation of gene expression correlating with these genes becoming more internally located within nuclei. Chromosome territories, containing these genes, were also found to alter their nuclear position during the in vitro adipogenesis model, with the most dramatic repositioning being SSC4 that moved from the nuclear periphery towards the nuclear interior. We found that during in vitro adipogenesis chromosome territories decondensed and the genes were found on loops and projections of chromatin, away from the main body of the chromosomes. From our data, it appears that the temporal repositioning of genes, emanating away from chromosomes, during adipogenesis is correlated with gene activity, supporting models of the involvement of spatial genome repositioning in regulating gene expression and the nuclear interior being an important region of the nucleus for transcription. PMID:19585140

Szczerbal, Izabela; Foster, Helen A; Bridger, Joanna M

2009-10-01

353

Risk factors and visual results in cases of LASIK flap repositioning due to folds or dislocation: case series and literature review.  

Science.gov (United States)

The presence of a corneal flap is a hallmark of laser in situ keratomileusis (LASIK), which offers advantages in terms of speed of visual recovery; however, it also carries the risk of postoperative flap displacement. We conducted a retrospective review of all consecutive eyes on which LASIK was performed by one single surgeon at an ophthalmological institute in Colombia between May 2005 and January 2011, looking for eyes that required flap repositioning. Demographic data, preoperative refraction, hinge position, and visual outcomes following flap repositioning were evaluated. A literature review on the subject was also conducted. We found 37 eyes on which flap repositioning was performed-12 eyes (32.4 %) with subluxation and 25 eyes (67.6 %) with folds; 21 eyes (56.8 %) had a temporal hinge and 16 eyes (43.2 %) had a superior hinge. With regard to the total number of eyes on which LASIK was performed (2,595), the overall incidence was 1.4 %. Sixteen out of 2,093 eyes (0.8 %) with a superior hinge and 21 out of 502 eyes (4.2 %) with a temporal hinge had flap-related postoperative complications (p < 0.00). A final best-corrected visual acuity (BCVA) between 20/20 and 20/25 was found in 75.7 % and a final BCVA between 20/30 and 20/40 was found in 21.6 %. Only one eye had less than 20/40 (previous amblyopia). From the eight eyes with a BCVA between 20/30 and 20/40, three had residual microstriae and one had corneal haze. Six eyes (16.2 %) lost two or more lines of BCVA. Flap subluxation or folds requiring flap repositioning were significantly more frequent when a temporal hinge was used. PMID:23605593

Galvis, Virgilio; Tello, Alejandro; Guerra, Alfredo R; Rey, Juan J; Camacho, Paul A

2014-02-01

354

Postoperative skeletal stability and accuracy of a new combined Le Fort I and horseshoe osteotomy for superior repositioning of the maxilla.  

Science.gov (United States)

Postoperative skeletal stability and accuracy were evaluated in a combination of Le Fort I and horseshoe osteotomies for superior repositioning of maxilla in bi-maxillary surgeries in 19 consecutive patients. 9 underwent Le Fort I osteotomy alone (preoperative planned superior movement 3.5 mm). The maxilla was osteotomized and fixed with 4 titanium Le Fort plates followed by bilateral sagittal split ramus osteotomy of the mandible, fixed with 2 semi-rigid titanium miniplates. Maxillomandibular fixation was performed for 1 week. Lateral cephalograms were obtained preoperatively, 1 week postoperatively, 3, 6, 12 months later. The changes in point A, point of maxillary tuberosity, and upper molar mesial cusp tip were examined. Discrepancy between the planned and measured superior movement of the maxilla in the Le Fort I and combination groups was 0.30 and 0.23 mm, respectively. The maxillae in both groups were repositioned close to their planned positions during surgery. 1 year later, both groups showed skeletal stability with no significant postoperative changes. When high superior repositioning of the maxilla is indicated, horseshoe osteotomy combined with Le Fort I is reliable and useful for accuracy and postoperative stability. PMID:19664907

Yoshioka, I; Khanal, A; Kodama, M; Furuta, N; Tominaga, K

2009-12-01

355

Magnetic resonance imaging of lumbar spine  

International Nuclear Information System (INIS)

Sixteen patients including 13 cases with disk herniation and 3 cases with spondylosis of lumbar spine were examined on a resistive MRI system operating at 0.1 T. All lesions were studied with both multiple spin echo (MSE) and low flip angle gradient echo (LF) techniques to evaluate which technique is more effective in detecting the disk degeneration and the indentation on subarachnoid space. MSE images were obtained with repetition time (TR) of 1100-1500 ms or cardiac gating, an echo time (TE) of 30, 60, 90, 120, 150, and 180 ms symmetrical 6 echoes, and total acquisition time of more than 281 sec. LF images were obtained with TR of 500, 250, and 100 ms, TE of 18 ms, a flip angle of 30 degree, and total acquisition time of 128 sec. Eleven lesions of spinal disk degeneration and 12 of indentation on subarachnoid space were detected with LF. On the other hand, 26 lesions of spinal disk degeneration and 38 of indentation on subarachnoid space were detected with MSE. Although the parameters of LF employed in this study were relatively effective to emphasize T2*-based contrast, the ability of LF in detection of spinal disk degeneration and indentation on subarachnoid space is less than that of MSE. Signal contrast to noise ratios for normal disk and degenerative disk, epidural-fat and disk herniated material, CSF and disk herniated material, and epidural-fat and CSF were less than 4 with LF, but more than 4 with MSE. This difference of contrast to noise ratio between MSE and LF was one of the main causes of the difference of the detection rate of spinal disk degeneration and indentation on subarachnoid space. (author)

1989-01-01

356

Gota axial / Gout in the spine  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese A gota axial pode afetar todos os segmentos da coluna vertebral. Ela se manifesta como dor nas costas, dor associada com sintomas neurológicos, e como comprometimento neurológico sem dor em 17,9%, 75,8% e 4,2% dos casos, respectivamente. Essas manifestações foram a primeira apresentação da gota em m [...] uitos pacientes. Embora radiografias, bem como tomografia computadorizada e especialmente ressonância magnética, possam ser muito sugestivos, análises histopatológicas, citológicas e pesquisa de cristais são o padrão ouro de diagnóstico. Na maioria dos casos que envolveram manifestações neurológicas, o paciente foi submetido à cirurgia, levando a resultados satisfatórios. Há, no entanto, alguns relatos de recuperação total após o tratamento clínico habitual para gota, o que sugere que esse tratamento pode ser a opção inicial para os indivíduos com histórico de gota e sinais radiológicos de envolvimento axial. Abstract in english Axial gout can affect all segments of the spine. It is manifested as back pain, as pain associated with neurological symptoms, and as neurological impairment without pain in 17.9%, 75.8% and 4.2% of cases, respectively. These manifestations were the first presentation of gout in many patients. Altho [...] ugh x-rays as well as computed tomography and especially magnetic resonance scans can be very suggestive, histopathological, cytological and crystal analyses are the diagnostic gold standard. In most cases involving neurological manifestations, the patient underwent surgery, leading to satisfactory results. There are, however, some reports of full recovery following the usual clinical treatment for gout, suggesting that such treatment may be the initial option for those subjects with a history of gout and radiological findings of axial involvement

Eduardo Massato, Hasegawa; Filipe Martins de, Mello; Cláudia, Goldenstein-Schainberg; Ricardo, Fuller.

357

Repair of a submucous cleft palate by W-pushback and levator repositioning without incision to the nasal mucosa.  

Science.gov (United States)

The author created an innovative method of W-pushback and levator repositioning without having to make an incision to the nasal mucosa for submucous cleft palate repair.The W-shaped mucoperiosteal flap is outlined where the 2 peaks of W are the alveolar processes of both canine teeth and the midpoint of W is the anterior limit of the cleft notch of the hard palate. A short incision, medial to and behind the maxillary tuberosity and curved forward onto the palate and extended forward just medial to the alveolar process, is joined by a second incision from the apex of the cleft to the region of the canine tooth. The W-shaped mucoperiosteal flap is raised until the midline notch of the hard palate is exposed. The nasal mucosa and abnormally inserted levator veli palatini muscle to the posterior border of the hard palate bone are detached. By leaving the nasal mucosa intact, the detached levator veli palatini muscle is approximated at the midline and so the zona pellucida is obliterated. The cleft uvulas are cut in half and closed. The approximated W-flap is joined to the small anterior flap by 1 or more sutures (the W-pushback).Three patients were operated on with this technique without serious complications.The author believes that this method can make the levator sling and increase the length of the soft palate without making an incision to the nasal mucosa. PMID:22421849

Hwang, Kun

2012-03-01

358

Vitrectomía pars plana y reimplante de lente intraocular en surco / Pars plana vitrectomy and intraocular lens repositioning in the sulcus  

Scientific Electronic Library Online (English)

Full Text Available SciELO Cuba | Language: Spanish Abstract in spanish Se presentó un caso de lente intraocular luxado a vítreo en paciente con conteo bajo de células endoteliales e intolerancia a lentes de contacto. Se practicó vitrectomía pars plana con reimplante de lente en surco ciliar con el objetivo de demostrar la fiabilidad de la técnica para casos que present [...] en condiciones adecuadas y situaciones especiales. Se revisó la bibliografía para conocer las tendencias actuales con respecto al manejo de esta patología. El paciente alcanzó una agudeza visual de 20/30. El lente permaneció estable en el surco 3 meses después de practicada la vitrectomía. El manejo de esta entidad debe ser personalizado. La técnica utilizada debe ser siempre la primera opción de tratamiento y parece ser segura en casos cuidadosamente escogidos. Abstract in english A case of dislocated intraocular lens moved to the vitreous cavity in a patient with low endothelial cell count and contact lens intolerance was reported. A pars plana vitrectomy with lens repositioning was performed to demonstrate the safety of this technique for some special cases under adequate c [...] onditions. The literature was reviewed to learn about the current management of this pathology. Finally, patient's best visual acuity was 20/30. The stability of the lens was confirmed three month l after the vitrectomy. Management of this disorder should be customized. This technique should be considered as the first option of treatment and seems to be safe in selected cases.

Alejandro, Guerra García; Luis, Curbelo Cunill; Frank, Eguía Martínez; María del Carmen, Rivas Canino.

359

Accuracy of maxillary repositioning in two-jaw surgery with conventional articulator model surgery versus virtual model surgery.  

Science.gov (United States)

The purpose of this study was to compare the accuracy of maxillary repositioning using the recently introduced computerized virtual model surgery (VMS) with conventional articulator model surgery (AMS). Forty-two patients who had undergone bimaxillary surgery were investigated retrospectively in this study. The patients were divided into two groups: conventional AMS (n = 23) and VMS (n = 19) for intermediate splint fabrication in maxillary positioning. Planned surgical movements and actual postsurgical changes of the lateral and frontal cephalometric measurements were compared. Although variations from the planned surgical movements were relatively small, both methods had statistically significant errors in some of the linear measurements. Both groups had a similar range of errors. The overall absolute mean discrepancy between the planned and actual surgical movements for the linear measurements was 1.17 mm (0-3.6 mm) in AMS and 0.95 mm (0-3.2 mm) in VMS. Of the total measurements, measurements reflecting a surgical discrepancy of more than 2 mm or 2° comprised 12.0% of the cases in AMS and 7.9% in VMS. The surgical accuracy of maxillary positioning with VMS was comparable to conventional AMS. Because VMS has the definitive advantage of eliminating the complex laboratory step and shortening the laboratory time, this can be accepted as an alternative to AMS. PMID:24462125

Kwon, T-G; Choi, J-W; Kyung, H-M; Park, H-S

2014-06-01

360

Diagnostic value of high resolutional computed tomography of spine  

Energy Technology Data Exchange (ETDEWEB)

Non-enhanced high resolution computed tomography provide clear visualization of soft tissue in the canal and bony details of spine, particularly of the lumbar spine. We observed 70 cases of spine CT using GE CT/T 8800 scanner during the period from Dec. 1982 to Sep. 1983 at Jeonbug National University Hospital. The results were as follows: 1. The sex distribution of cases were 55 males and 15 females : age was from 17 years to 67 years; sites were 11 cervical spine, 5 thoracic spine and 54 lumbosacral spine. 2. CT diagnosis showed 44 cases of lumbar disc herniation, 7 cases of degenerative disease, 3 cases of spine fracture and each 1 cases of cord tumor, metastatic tumor, spontaneous epidural hemorrhage, epidural abscess, spine tbc., meningocele with diastematomyelia. 3. Sites of herniated nucleus pulposus were 34 cases (59.6%) between L4-5 interspace and 20 cases (35.1%) between L5-S1 interspace. 13 cases (29.5%) of lumbar disc herniation disclosed multiple lesions. Location of herniation were central type in 28 cases(49.1%), right-central type in 12 cases(21.2%), left-central type in 11 cases (19.2%) and far lateral type in 6 cases(10.5%). 4. CT findings of herniated nucleus pulposus were as follows : focal protrusion of posterior disc margin and obliteration of anterior epidural fat in all cases, dural sac indentation in 26 cases(45.6%), soft tissue mass in epidural fat in 21 cases(36.8%), displacement or compression of nerve root sheath in 12 cases(21%). 5. Multiplanar reformatted images and Blink mode provide more effective evaluation about definite level and longitudinal dimension of lesion, such as obscure disc herniation, spine fracture, cord tumor and epidural abscess. 6. Non-enhanced and enhanced high resolutional computed tomography were effectively useful in demonstrating compression or displacement of spinal cord and nerve root, examing congenital anomaly such as meningocele and primary or metastatic spinal lesions.

Yang, S. M.; Im, S. K.; Sohn, M. H.; Lim, K. Y.; Kim, J. K.; Choi, K. C. [Jeonbug National University College of Medicine, Seoul (Korea, Republic of)

1984-03-15

 
 
 
 
361

Diagnostic value of high resolutional computed tomography of spine  

International Nuclear Information System (INIS)

Non-enhanced high resolution computed tomography provide clear visualization of soft tissue in the canal and bony details of spine, particularly of the lumbar spine. We observed 70 cases of spine CT using GE CT/T 8800 scanner during the period from Dec. 1982 to Sep. 1983 at Jeonbug National University Hospital. The results were as follows: 1. The sex distribution of cases were 55 males and 15 females : age was from 17 years to 67 years; sites were 11 cervical spine, 5 thoracic spine and 54 lumbosacral spine. 2. CT diagnosis showed 44 cases of lumbar disc herniation, 7 cases of degenerative disease, 3 cases of spine fracture and each 1 cases of cord tumor, metastatic tumor, spontaneous epidural hemorrhage, epidural abscess, spine tbc., meningocele with diastematomyelia. 3. Sites of herniated nucleus pulposus were 34 cases (59.6%) between L4-5 interspace and 20 cases (35.1%) between L5-S1 interspace. 13 cases (29.5%) of lumbar disc herniation disclosed multiple lesions. Location of herniation were central type in 28 cases(49.1%), right-central type in 12 cases(21.2%), left-central type in 11 cases (19.2%) and far lateral type in 6 cases(10.5%). 4. CT findings of herniated nucleus pulposus were as follows : focal protrusion of posterior disc margin and obliteration of anterior epidural fat in all cases, dural sac indentation in 26 cases(45.6%), soft tissue mass in epidural fat in 21 cases(36.8%), displacement or compression of nerve root sheath in 12 cases(21%). 5. Multiplanar reformatted images and Blink mode provide more effective evaluation about definite level and longitudinal dimension of lesion, such as obscure disc herniation, spine fracture, cord tumor and epidural abscess. 6. Non-enhanced and enhanced high resolutional computed tomography were effectively useful in demonstrating compression or displacement of spinal cord and nerve root, examing congenital anomaly such as meningocele and primary or metastatic spinal lesions

1984-03-01

362

Diagnosis of cervical spine fractures with multislice helical CT  

International Nuclear Information System (INIS)

Purpose: It is the aim of this study to investigate the efficiency of multislice helical CT for the diagnosis of cervical spine fractures. The advantages of this technique are demonstrated by case reports. Material and Methods: The entire cervical spine or selected vertebral bodies of 66 patients with cervical spine fractures known from preceding plain films were scanned with a multislice helical CT. The CT-scans were obtained with a slice thickness of 1,25 mm and with two different pitches (0,75 or 1,5) and table speeds (3,75 or 7,5 mm/rot.). Additionally, sagittal and coronal reformations were performed. Results: The mean scantime for the cervical spine was 13 seconds. High quality sagittal and coronal reformations were obtained from axial images within a few minutes. Fractures of the dens (n = 17) and of the vertebral body of C3-C7 (n = 12) occured predominantly. Conclusion: Multislice helical CT is an effective tool to diagnose fractures of the cervical spine rapidly and exactly. (orig.)

2001-01-01

363

Normal and abnormal spine and thoracic cage development  

Directory of Open Access Journals (Sweden)

Full Text Available Development of the spine and thoracic cage consists of a complex series of events involving multiple metabolic processes, genes and signaling pathways. During growth, complex phenomena occur in rapid succession. This succession of events, this establishment of elements, is programmed according to a hierarchy. These events are well synchronized to maintain harmonious limb, spine and thoracic cage relationships, as growth in the various body segments does not occur simultaneously at the same magnitude or rate. In most severe cases of untreated progressive early-onset spinal deformities, respiratory insufficiency and pulmonary and cardiac hypertension (cor pulmonale, which characterize thoracic insufficiency syndrome (TIS, can develop, sometimes leading to death. TIS is the inability of the thorax to ensure normal breathing. This clinical condition can be linked to costo-vertebral malformations (e.g., fused ribs, hemivertebrae, congenital bars, neuromuscular diseases (e.g., expiratory congenital hypotonia, Jeune or Jarcho-Levin syndromes or to 50% to 75% fusion of the thoracic spine before seven years of age. Complex spinal deformities alter normal growth plate development, and vertebral bodies become progressively distorted, perpetuating the disorder. Therefore, many scoliotic deformities can become growth plate disorders over time. This review aims to provide a comprehensive review of how spinal deformities can affect normal spine and thoracic cage growth. Previous conceptualizations are integrated with more recent scientific data to provide a better understanding of both normal and abnormal spine and thoracic cage growth.

Federico Canavese

2013-01-01

364

Scoring system for prediction of metastatic spine tumor prognosis  

Science.gov (United States)

Assessing the prognosis before treatment for metastatic spine tumor is extremely important in therapy selection. Therefore, we review some prognostic scoring systems and their outcomes. Articles with combinations of two keywords among “metastatic spine tumor” and “prognosis”, “score”, “scoring system”, “predicting”, or “life expectancy” were searched for in PubMed. As a result, 236 articles were extracted. Those referring to representative scoring systems about predicting the survival of patients with metastatic spine tumors were used. The significance and limits of these scoring systems, and the future perspectives were described. Tokuhashi score, Tomita score, Baur score, Linden score, Rades score, and Katagiri score were introduced. They are all scoring systems prepared by combining factors that affect prognosis. The primary site of cancer and visceral metastasis were common factors in all of these scoring systems. Other factors selected to influence the prognosis varied. They were useful to roughly predict the survival period, such as, “more than one year or not” or “more than six months or not”. In particular, they were utilized for decision-making about operative indications and avoidance of excessive medical treatment. Because the function depended on the survival period in the patients with metastatic spine tumor, it was also utilized in assessing functional prognosis. However, no scoring system had more than 90% consistency between the predicted and actual survival periods. Future perspectives should adopt more oncological viewpoints with adjustment of the process of treatment for metastatic spine tumor.

Tokuhashi, Yasuaki; Uei, Hiroshi; Oshima, Masashi; Ajiro, Yasumitsu

2014-01-01

365

Prevention of spine deforimities in adoloscents due to inaduquate posture  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction. The spine deformities tend to increase, and in 90% of children they change the quality of life. The aim of this study was to determine the percents of spinal deformity in our population of adolescents, and long bad posture in and out of school as a factor for its increase. Material and methods. The study included 124 adolescents attending High Musical School in Bitola and Skopje, who underwent four standard spine tests and an interview. Results. According to the test 3, 50% of the examined adolescents in Bitola and 69% in Skopje had the postural spine deformity, the average being 59.5%. The results obtained by the questionnaire showed that 50% of adolescents did not have any physical activity out of school, the longest daily activity, lasting four hours, in 48% of the examinees was practising their musical instruments; 40% of the examinees spent two hours watching TV or using the computer, whereas 18% did not use any of them at all. Conclusion. The bad spine posture tends to deteriorate in adolescents and the factor influencing this result should be established by studies aimed at determining the effects of physical activity on reducing such deformities, since the specific type of their education induces the risk of developing pain and early degenerative changes of the spine, which are predominant in the professionals.

Lazovi? Milica

2010-01-01

366

Modern posterior screw techniques in the pediatric cervical spine.  

Science.gov (United States)

Treatment of children with cervical spine disorders requiring fusion is a challenging endeavor for a variety of reasons. The size of the patients, the corresponding abnormal bony anatomy, the inherent ligamentous laxity of children, and the relative rarity of the disorders all play a part in difficulty of treatment. The benefits of modern posterior cervical instrumentation in children, defined as rigid screw-rod systems, have been shown to be many including: improved arthrodesis rates, diminished times in halo-vest immobilization, and improved reduction of deformities. The anatomy of children and the corresponding pathology seen frequently is at the upper cervical spine and craniocervical junction given the relatively large head size of children and the horizontal facets at these regions predisposing them to instability or deformity. Posterior screw fixation, while challenging, allows for a rigid base to allow for fusion in these upper cervical areas which are predisposed to pseudarthrosis with non-rigid fixation. A thorough understanding of the anatomy of the cervical spine, the morphology of the cervical spine, and the available screw options is paramount for placing posterior cervical screws in children. The purpose of this review is to discuss both the anatomical and clinical descriptions related to posterior screw placement in the cervical spine in children. PMID:24829871

Hedequist, Daniel J

2014-04-18

367

Cervical spine trauma: Radiologic manifestations and imaging algorithms  

International Nuclear Information System (INIS)

Cervical spine trauma is very critical injury that is incurred most frequently in automobile accidents, mining incidents, and war. Injuries of the cervical spine produce neurologic damage in approximately 40% of cases, whereas injuries of the thoracolumbar junction produce neurologic damage in 4% and injuries of the thoracic spine do so in 10%. Radiology has a fundamental role in the recognition and follow-up of patients. Radiologists should be quite familiar with the imaging algorithms and various radiologic manifestations of cervical spine injuries. In this paper, techniques of examining severely injured patients as well as those with slight or questionable injuries are demonstrated. Indications and limitations of various diagnostic procedures (plain film radiography, tomography, CT, and MR imaging) are discussed. A systematic plan for the study of the cervical spine with an emphasis on joints, bones, ligaments and soft tissues (JO-B-LI-ST) is introduced. Mechanisms of injury and the stability or instability of the injuries are presented. Plain radiography as well as other imaging modalities are used to demonstrate the most important forms of injuries at various levels. Follow-up of some of the treated cases is shown. The late complications of spinal cord damage in closed injuries and open wounds (urinary stones, myositis, ossificans, contractures, fractures, disuse atrophy, and bone infections) are presented at the end

1987-12-04

368

Magnetic resonance imaging (MRI) anatomy of the ovine lumbar spine.  

Science.gov (United States)

Although the ovine spine is a useful research model for intervertebral disc pathology and vertebral surgery, there is little peer-reviewed information regarding the MRI anatomy of the ovine spine. To describe the lumbar spine MRI anatomy, 10 lumbar segments of cadaver ewes were imaged by 1.5-Tesla MR. Sagittal and transverse sequences were performed in T1 and T2 weighting (T1W, T2W), and the images were compared to gross anatomic sagittal and transverse sections performed through frozen spines. MRI was able to define most anatomic structures of the ovine spine in a similar way as can be imaged in humans. In both T1W and T2W, the signals of ovine IVDs were similar to those observed in humans. Salient anatomic features were identified: (1) a 2- to 3-mm linear zone of hypersignal was noticed on both extremities of the vertebral body parallel to the vertebral plates in sagittal planes; (2) the tendon of the crura of the diaphragm appeared as a hypointense circular structure between hypaxial muscles and the aorta and caudal vena cava; (3) dorsal and ventral longitudinal ligaments and ligamentum flavum were poorly imaged; (4) no ilio-lumbar ligament was present; (5) the spinal cord ended between S1-S2 level, and the peripheral white matter and central grey matter were easily distinguished on T1W and T2W images. This study provides useful reference images to researchers working with ovine models. PMID:23668479

Nisolle, J F; Wang, X Q; Squélart, M; Hontoir, F; Kirschvink, N; Clegg, P; Vandeweerd, J M

2014-06-01

369

Analysis of cervical spine function in healthy persons  

International Nuclear Information System (INIS)

Radiograms were taken of subjects with no symptoms of cervical spine problems; the cervical spine was evaluated in the spontaneous posture and at maximal flexion and extension. The position and movement of the vertebra, intervertebral height and gliding were calculated. The results showed that (1) lordosis in women occurred less pronouncedly than in men, and that there was an increase with age; (2) C 2-3 was the least flexible segment and mobility increased in the caudal direction; mobility decreased with age and the segments of the lower cervical spine with the highest mobility decreased the most; (3) all posterior and ventral intervertebral heights showed a decrease with age at C 5-6 and C 6-7; (4) vertebral gliding decreased with age. (orig.)

1990-01-01

370

MR manifestations of vertebral artery injuries in cervical spine trauma  

International Nuclear Information System (INIS)

To assess the diagnostic efficacy of magnetic resonance (MR) imaging in the detection of a vertebral artery injury occurring from major cervical spine trauma. Conventional MR findings of 63 patients and 63 control subjects were compared to detect a possible change in the vertebral arteries resulted from trauma. Plain films, CT and clinical records were also reviewed to correlate the degree of cervical spine injury with vascular change. Nine cases of absent flow signals in vessel lumen were observed in eight patients and one was observed in the control group. Patients more frequently demonstrated other abnormalities such as intraluminal linear signals (n=3) or focal luminal narrowing (n=9) but there was no statistical significance. There was a close relationship between degree of cord damage and occlusion of the vertebral artery. Conventional MR imaging is useful in the detection of vertebral artery occlusion resulting from cervical spine trauma

1996-11-01

371

Significance of prevertebral soft tissue measurement in cervical spine injuries  

International Nuclear Information System (INIS)

Objective: The objective of this study was to evaluate the diagnostic value of prevertebral soft tissue swelling in cervical spine injuries. Materials and methods: A group of 107 consecutive patients with suspected injuries of the cervical vertebrae were reviewed retrospectively to identify the presence of prevertebral soft tissue swelling and to investigate the association of prevertebral soft tissue swelling with the types and degrees of cervical spine injuries. Results: Prevertebral soft tissue swelling occurred in 47 (43.9%) patients. Of the 47 patients, 38 were found with bony injury and nine were without. The statistic difference was significant (P0.05). Anterior element injuries in the cervical vertebrae had widening of the prevertebral soft tissue more than posterior element injuries (P<0.05). Conclusion: The diagnostic value of prevertebral soft tissue swelling for cervical spine injuries is significant, but the absence of this sign does not mean that further image evaluation can be spared

2004-07-01

372

Region-based enhancement of chest and cervical spine radiographs  

Science.gov (United States)

We have developed a region-based image processing method to enhance selective radiodense regions on digital radiographs. We employ a wavelet filtering technique to locate the radiodense regions-of-interest and then apply different degrees of enhancement procedure to them. The enhancement procedure is based on an unsharp masking technique controlled by a set of sigmoidal functions. The method was tested on computed chest radiographs to improve the visualization of the mediastinum and radiodense spine areas. The enhanced chest images showed improved visualization in the mediastinum area, and the visibility of vascular structures which were obscured by the diaphragm and mediastinum was improved. To demonstrate the method's potential in other medical image processing tasks, we applied it to cervical spine images. The processed cervical spine images also showed better visualization of the seventh cervical vertebrae and the first thoracic vertebrae in the high radiodense area caused by the superimposition of the patient's shoulder tissue over these regions of interest.

Lin, Jyh-Shyan; Steller Artz, Dorothy E.; Li, Huai; Legendre, Kevin; Freedman, Matthew T.; Mun, Seong K.

1996-04-01

373

Epithelioid sarcoma of the spine: a case report and review  

Directory of Open Access Journals (Sweden)

Full Text Available Epithelioid sarcoma is a rare malignant soft tissue neoplasm commonly involving extremities of young adults and rarely occurring in the trunk area. It re-sembles a chronic inflammatory process and mimics benign reactive granuloma or other benign diseases. Despite its indolence and slow growth, the prognosis is poor with high recurrence and early lymph node spreading and hematogeneous distant metastasis. Involvement of the spine is extremely rare and diffi-cult to diagnose correctly in clinical presentation and pathology. We describe our experience a case of epi-thelioid sarcoma involving lumbar spine. A pre-ope- rative spine MRI showed a large solid and necrotic paraspinal mass which extended into the spinal canal with cord compression, and bone destruction. Final correct diagnosis was confirmed by immunohisto-chemical studies. When young adults present with a spinal lesion that has unusual large necrotic soft tissue mass, immunohistochemical studies are recommended for promptly determining the possibility of spinal epithelioid sarcoma.

Jeong Hyun Yoo

2011-06-01

374

Improvement of cervical spine radiography in the supine position  

International Nuclear Information System (INIS)

It has been difficult to obtain accurate radiographic images of the oblique cervical spine in the supine position. We developed a new technique that combined the sliding top bucky table and a radiographic supporting device. Our technique improved the reproducibility of images because the geometry was always the same. Further, no special technique is required. The radiographic magnification factor of the supine position was approximately 13% larger than that of the standing position, but image quality and clinical evaluation were almost the same. In conclusion, our new technique for oblique projection of cervical spine radiography in the supine position does not require co-workers to hold the patient. In addition, this technique provided cervical spine radiography with reduced discomfort for the patient. (author)

1998-03-01

375

Detection of breast cancer metastases in the cervical spine  

International Nuclear Information System (INIS)

Thirty women with breast cancer and indications of possible cervical spine metastases underwent skeletal scintigraphy, conventional radiography, MR imaging and CT. By combining all examinations a diagnosis was settled in each patient and the different imaging techniques were compared. For all of the 26 patients with metastases in the cervical spine to correct diagnosis was found with MR imaging and CT. Both modalities also revealed paravertebral tumour growth, MR (n=8) more than CT (n=3). The sensitivity of skeletal scintigraphy in detecting metastases in the cervical spine was rather low, but as these examinations cover the whole body they are still convenient screening procedures, and combined with conventional radiography of selected areas are probably sufficient in many cases. Supplementary examinations with CT or MR would be valuable in patients with equivocal findings at screening for metastases or with clinical indications of metastases that remain unexplained after scintigraphy and radiography. (orig.)

1993-11-01

376

Detection of breast cancer metastases in the cervical spine  

Energy Technology Data Exchange (ETDEWEB)

Thirty women with breast cancer and indications of possible cervical spine metastases underwent skeletal scintigraphy, conventional radiography, MR imaging and CT. By combining all examinations a diagnosis was settled in each patient and the different imaging techniques were compared. For all of the 26 patients with metastases in the cervical spine to correct diagnosis was found with MR imaging and CT. Both modalities also revealed paravertebral tumour growth, MR (n=8) more than CT (n=3). The sensitivity of skeletal scintigraphy in detecting metastases in the cervical spine was rather low, but as these examinations cover the whole body they are still convenient screening procedures, and combined with conventional radiography of selected areas are probably sufficient in many cases. Supplementary examinations with CT or MR would be valuable in patients with equivocal findings at screening for metastases or with clinical indications of metastases that remain unexplained after scintigraphy and radiography. (orig.).

Petren-Mallmin, M. (Depts. of Diagnostic Radiology and Oncology, Univ. Hospital, Uppsala (Sweden)); Andreasson, I. (Depts. of Diagnostic Radiology and Oncology, Univ. Hospital, Uppsala (Sweden)); Nyman, R. (Depts. of Diagnostic Radiology and Oncology, Univ. Hospital, Uppsala (Sweden)); Hemmingsson, A. (Depts. of Diagnostic Radiology and Oncology, Univ. Hospital, Uppsala (Sweden))

1993-11-01

377

Spinal Stenosis Treatment: Little Benefit from Corticosteroid Injections for Common Cause of Spine-Related Pain  

Science.gov (United States)

... benefit from corticosteroid injections for common cause of spine-related pain, AHRQ-funded study says Press Release ... benefit from corticosteroid injections for common cause of spine-related pain, AHRQ-funded study says. July 2014. ...

378

Recurrent spine surgery patients in hospital administrative database  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction: Hospital patient databases are typically used by administrative staff to estimate loss-profit ratios and to help with the allocation of hospital resources. These databases can also be very useful in following rehospitalization. This paper studies the recurrence of spine surgery patients in our hospital population based on administrative data analysis. Methods: Hospital data on 4,958 spine surgery patients operated between 2002 and 2009 were retrospectively reviewed. After sorting the cohort per ascending discharge date, the patient official name, consisting of first, middle and last names, was used as the variable determining duplicate cases in the SPSS statistical program, designating the first case in each group as primary. Yearly recurrence rate and change in procedure distribution were studied. In addition, hospital charges and length of stay were compared using the Wilcoxon-Mann-Whitney test. Results: Of 4,958 spine surgery patients 364 (7.3% were categorized as duplicate cases by SPSS. The number of primary cases from which duplicate cases emerged was 327 meaning that some patients had more than two spine surgeries. Among primary patients (N=327 the percentage of excision of intervertebral disk procedures was 33.3% and decreased to 15.1% in recurrent admissions of the same patients (N=364. This decrease was compensated by an increase in lumbar fusion procedures. On the other hand, the rate of cervical fusion remained the same. The difference in hospital charges between primary and duplicate patients was $2,234 for diskectomy, $6,319 for anterior cervical fusion, $8,942 for lumbar fusion – lateral technique, and $12,525 for lumbar fusion – posterior technique. Recurrent patients also stayed longer in hospital, up to 0.9 day in lumbar fusion – posterior technique patients. Conclusion: Spine surgery is associated with an increasing possibility of additional spine surgery with rising invasiveness and cost.

M. Sami Walid

2012-02-01

379

Clinical implications of alignment of upper and lower cervical spine  

Directory of Open Access Journals (Sweden)

Full Text Available Aims and Objectives: The alignment of upper and lower cervical spine is presumed to be closely interrelated and the knowledge of this is mandatory when performing occipito-cervical and upper cervical fusions. The aim of this study was to establish standard values for upper and lower cervical spine alignment in the Indian population. Materials and Methods: Five hundred eighteen asymptomatic volunteers (261 males and 257 females between 12 and 80 years of age underwent lateral radiography with their neck in the neutral position. Angles for occipital to 2nd cervical (Oc-C2, 1st to 2nd cervical (C1-C2 and sagittal alignment of 2nd to 7th cervical vertebrae (C2-C7 were measured. Statistical analyses were performed using a statistical package SPSS 10 for windows and the students ?t? test. Results: The mean Oc-C2, C1-C2 and C2--C7 angles were 14.66 + 9.5°, 25.6 + 7.9° and 16.8 + 12.7° in male, while same angles in female were 15.59 + 8.26°, 26.9 + 6.8° and 9.11 + 10.4° respectively. Weak statistically significant negative correlation was observed between the measured angles of the upper (Oc-C2 and C1-C2 and lower (C2-C7 cervical spines, which means if the lordosis of the occiput and upper cervical spine increases (if the Oc-C2 angle increases, the alignment of lower cervical spine becomes kyphotic and vice versa. This negative correlation was stronger between the Oc-C2 and C2-C7 angles than between the C1-C2 and C2-C7 angles. Conclusions: Relationship between alignment of the upper and the lower cervical spine should be taken into consideration when performing cervical fusion.

Sherekar S

2006-01-01

380

Repair of esophageal perforation due to anterior cervical spine instrumentation.  

Science.gov (United States)

The complication of esophageal perforation after anterior cervical spine fusion for cervical spine disease is rare but potentially fatal. We describe two cases of esophageal perforation found by esophagoscopic visualization. In one patient, primary closure could not be achieved, and a submental island flap was used to repair the defect. In the second patient, primary closure was achieved and a pectoralis major flap was interposed between the closure and the residual instrumentation. Postoperatively, both patients had no evidence of persistent perforation and had resolution of preoperative symptoms. PMID:20232412

Kau, Ryan L; Kim, Namou; Hinni, Michael L; Patel, Naresh P

2010-04-01

 
 
 
 
381

Osteoid Osteoma of Cervical Spine in two adjacent Vertebrae  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Osteoid osteoma is a benign bone tumor, mainly seen in 10-30 years male. Spine is a relatively common site and almost always, posterior elements are involved. Plain X-Ray-, CT scan and Isotope scan help to identify and localize spine lesions. We described one 18 years old boy with 3 years low neck pain. Isotope scan, MRI and CT scan showed two lesions in C7 and T1. Gross inspection and histopathology examination confirmed osteoid osteoma in two adjacent vertebrae which has not been reported e...

MR Etemadifar; Ar, Ebrahimzadeh; Karimian, M.

2005-01-01

382

Biphasic synovial sarcoma in the cervical spine: Case report  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Abstract Synovial sarcoma is a rare malignant neoplasm of soft tissue that typically arising near large joints of the upper and lower extremities in young adult males. Only 3% of these neoplasms have been found to arise in the head and neck region. To our knowledge, there are limited reports in the literature of this neoplasm in the cervical spine. A case of biphasic synovial sarcoma of the cervical spine is reviewed. A 29 year-old male presented with pain on the left side of...

2011-01-01

383

Biometric X-ray-function diagnosis of the cervical spine  

International Nuclear Information System (INIS)

Subject of this study was the investigation of functional disorders of the cervical spine and their possible causal relation with the symptoms and signs of pathological cervical images. In order to approach this investigation with objectively measurable time criteria, functional X-ray diagnostics results to be the appropriate method. From the results obtained in individual and statistical group examinations as well as in examinations of the longitudinal section the conclusion is drawn that a functional disorder of the cervical spine may provoke a cervical syndrome. (APR)

1981-12-01

384

Interobserver discrepancies in distance measurements from lumbar spine CT scans  

International Nuclear Information System (INIS)

Lumbar spine computed tomographic (CT) scans of 10 patients were examined independently at two levels by five experienced radiologists. At each level the minimum midline sagittal diameter was measured, and at each intervertebral space the left foramen was measured for its minimum diameter. Statistically significant differences were found between the measurements of different observers, differences that in a number of cases could have led to disagreement over whether or not stenosis was present. There were reasonably strong correlations between different observers' readings of midline sagittal diameters but generally not of foraminal diameters. Reasons for discrepancies between observers in spine CT measurements are reviewed briefly

1985-02-01

385

CT examination of the spine and the spinal canal  

International Nuclear Information System (INIS)

Analogous to its other fields of application, CT of the spine and the spinal canal has also already achieved a permanent place among the diagnostic methods. Numerically, CT studies of the cervical, thoracic and lumbar spine for our patient population with a total of 460 examinations are in the ratio 2:1:4.5. The essential advantages are improved differential diagnosis for many processes, the exact breakdown of the degree of extraspinal and intraspinal involvement in the change, the increasing limitation of myelography and last but not least the possibility of reducing cost. (orig.)

1982-01-01

386

Optimal computed-tomographic techniques for cervical spine imaging  

International Nuclear Information System (INIS)

The authors compare various techniques for optimal computed-tomographic imaging of the cervical spine and find that no single method is adequate for visualizing all anatomic structures. Thin sections are needed to obtain images of intervertebral disks, but thick sections are preferred to obtain images of the spinal cord. Spatial resolution is more important than contrast resolution when imaging the vertebrae. Small-body calibration is recommended for adequate cervical spine visualization, although some artifacts can be minimized when large-body calibration is used

1982-01-01

387

Study on calcium concentration in the spine by computed tomography  

International Nuclear Information System (INIS)

Calcium concentrations in the spine were estimated by a calculation method for calcium concentrations in bones using a whole body CT-scanner, EMI CT 5005/12. The CT value (EMI value) in decalcified bones was 19.7 +- 1.2. There was a linear relationship between CT values and calcium concentrations (0.83). Calcium concentrations in bone tissues were estimated from CT values. Calcium concentration in the spine showed its peak in both men and women in their twenties and thirties, and it decreased with aging. Expecially, calcium concentration in women decreased rapidly after the age of fifty. (Tsunoda, M.)

1980-01-01

388

Glycopyrrolate Induced Bilateral Angle Closure Glaucoma after Cervical Spine Surgery  

Digital Repository Infrastructure Vision for European Research (DRIVER)

To report a case of bilateral acute angle closure glaucoma (AACG) that occurred after cervical spine surgery with the use of glycopyrolate. A 59-year-old male who presented with severe bilateral bifrontal headache and eye pain that started 12 h postextubation from a cervical spine surgery. Neostigmine 0.05 mg/kg (4.5 mg) and glycopyrrolate 0.01 mg/kg (0.9 mg) were used as muscle relaxant reversals at the end of the surgery. Ophthalmic examination revealed he had bilateral AACG with plateau ir...

Jaroudi, Mahmoud; Fadi, Maalouf; Farah, Fadi; El Mollayess, Georges M.

2013-01-01

389

Segmentation of the vertebrate spine: from clock to scoliosis  

Science.gov (United States)

The body axis of vertebrates is composed of a serial repetition of similar anatomical modules, termed segments or metameres. This particular mode of organization is especially conspicuous at the level of the periodic arrangement of vertebrae in the spine. The segmental pattern is established during embryogenesis when the somites, the embryonic segments of vertebrates, are rhythmically produced from the paraxial mesoderm. This process involves the segmentation clock, a traveling oscillator that interacts with a maturation wave called the wavefront to produce the periodic series of somites. Recent studies have shed light on several aspects of the segmentation mechanism and provide a conceptual framework to explain human spine malformations, such as congenital scoliosis.

Pourquie, Olivier

2011-01-01

390

Spine imaging with FRODO pulses for motion artifact reduction  

International Nuclear Information System (INIS)

Motion artifacts commonly limit the diagnostic quality of spine images. We have developed a method that suppresses these artifacts using tailored radio-frequency pulses (FRODO pulses) to saturate proton magnetization over one or more precisely defined sections of tissue. Ghost artifacts from pulsatile flow in the heart and great vessels and from swallowing and respiration are suppressed. Wraparound artifact along the phase-encoding axis is also eliminated, permitting optimal orientation of the phase-encoding axis. A definitive solution for motion artifact in spine imaging has been achieved by combining the FRODO technique with flow-compensated spin-echo and fast gradient echo pulse sequences

1987-12-04

391

[Recommendations for the treatment of thoracolumbar and lumbar spine injuries].  

Science.gov (United States)

This paper gives recommendations for treatment of thoracolumbar and lumbar spine injuries. The recommendations are based on the experience of the involved spine surgeons, who are part of a study group of the "Deutsche Gesellschaft für Unfallchirurgie" and a review of the current literature. Basics of diagnostic, conservative, and operative therapy are demonstrated. Fractures are evaluated by using morphologic criteria like destruction of the vertebral body, fragment dislocation, narrowing of the spinal canal, and deviation from the individual physiologic profile. Deviations from the individual sagittal profile are described by using the monosegmental or bisegmental end plate angle. The recommendations are developed for acute traumatic fractures in patients without severe osteoporotic disease. PMID:21246343

Verheyden, A P; Hölzl, A; Ekkerlein, H; Gercek, E; Hauck, S; Josten, C; Kandziora, F; Katscher, S; Knop, C; Lehmann, W; Meffert, R; Müller, C W; Partenheimer, A; Schinkel, C; Schleicher, P; Schnake, K J; Scholz, M; Ulrich, C

2011-01-01

392

[The clinical value of transpedicular thoraco-lumbar spine stabilisation].  

Science.gov (United States)

The authors present the results of treatment of spine neoplastic disease using transpedicular stabilisation. The clinical material of 2004 year are 20 cases, 15 males (75%) and 5 female (25%), 19 of them were qualified to the surgical treatment (95%). Obtained outcomes permit authors to make confirmation that the transpedicular stabilisation of thoraco-lumbar spine as a surgical treatment of it's neoplastic disease decrease pain, improve neurological condition if spinal cord damage are not durable, makes easer the rehabilitation process and nursing care. PMID:17455528

Chrzanowski, Robert; Golec, Edward; Klauz, Grzegorz; Janeczko, Lukasz; Gierula, Tomasz

2006-01-01

393

The Relationship of SmokingOpioidAntidepressant Use and History of Spine Surgery  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Introduction: In a recent paper, smoking was shown to be an independent predictor of longterm continued opioid use in spine patients (Krebs et al. 2010). In this paper, we study the interaction of smoking with opioid and antidepressant use and the relationship with prior spine surgery and future spine surgery. Methods: Data on smoking, opioid and antidepressant use were retrospectively collected from 758 spine surgery inpatients [lumbar microdiskectomy (LMD), anterior cervical decompression a...

Walid Mohammad; Zaytseva Nadezhda

2010-01-01

394

Osteochondroma of the cervical spine: Report of two cases in preadolescent males  

International Nuclear Information System (INIS)

Although considered to be rare in the spine, osteochondromas are in fact found there as often as other benign bone tumors. Three percent of all osteochondromas occur in the spine, while forty percent of osteoblastomas are to be found there. Yet, because osteochondromas are so much more common overall than osteoblastomas, their actual occurrences in the spine can be expected to be equal. Two cases of osteochondroma of the cervical spine, one of which was diagnosed by computed tomography, are reported. (orig.)

1982-01-01

395

Prehospital clearance of the cervical spine: does it need to be a pain in the neck?  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Prehospital cervical spine (c?spine) immobilisation is common, despite c?spine injury being relatively rare. Unnecessary immobilisation results in a significant burden on limited prehospital and emergency department (ED) resources. This study aimed to determine whether the incidence of unnecessary c?spine immobilisation by ambulance personnel could be safely reduced through the implementation of an evidence?based algorithm. Following a training programme, complete forms on 103 patient...

Armstrong, B. P.; Simpson, H. K.; Crouch, R.; Deakin, C. D.

2007-01-01

396

Lateral radiological evaluation of transarticular screw placement in the lower cervical spine  

Digital Repository Infrastructure Vision for European Research (DRIVER)

This study assessed the ideal district of lateral radiograph in evaluation of transarticular screw placement in the lower cervical spine. To assess the ideal zone of lateral radiographs in determining the safe or hazardous locations of the screw tips during transarticular screw implantation in the lower cervical spine. Transarticular screw in the lower cervical spine had been used as an alternative technique to achieve posterior cervical spine stability. Injury to the spinal nerves caused by ...

Xu, Rongming; Zhao, Liujun; Chai, Bo; Ma, Weihu; Xia, Huajie; Wang, Guoping; Jiang, Weiyu

2009-01-01

397

Dendritic spines elongate after stimulation of group 1 metabotropic glutamate receptors in cultured hippocampal neurons  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Changes in the morphology of dendritic spines are correlated with synaptic plasticity and may relate mechanistically to its expression and stabilization. Recent work has shown that spine length can be altered by manipulations that affect intracellular calcium, and spine length is abnormal in genetic conditions affecting protein synthesis in neurons. We have investigated how ligands of group 1 metabotropic glutamate receptors (mGluRs) affect spine shape; stimulation of these receptors leads bo...

Vanderklish, Peter W.; Edelman, Gerald M.

2002-01-01

398

Cirugía de rescate (reubicación quirúrgica) en segundos molares inferiores impactados / Rescue surgery (surgical repositioning) of impacted lower second molars  

Scientific Electronic Library Online (English)

Full Text Available SciELO Spain | Language: Spanish Abstract in spanish La impactación de los segundos molares inferiores es una complicación de la erupción dentaria muy infrecuente, dado que su incidencia se cifra de un 0,03 a un 0,21 %. Se ha detectado en mayor frecuencia de forma unilateral que bilateral y es más usual en mandíbula que en maxilar. Presenta una ligera [...] predicción por el sexo masculino, y la inclinación mesial es la más habitual. Se han publicado una amplia variedad de aproximaciones terapéuticas, fundamentalmente apelando a técnicas quirúrgicas únicas o ayudadas de técnicas ortodóncicas, con el objeto de llevar al diente a su correcta posición, y que se engloban bajo el concepto de cirugía de rescate. En los casos resueltos con una reubicación del diente impactado, la extracción profiláctica del germen se ha propugnado como obligatoria. Presentamos el caso de una paciente de 12 años y 6 meses derivado al Master de Cirugía Bucal de la Universidad de Sevilla por presentar falta de erupción del segundo molar inferior izquierdo. El paciente fue derivado por su ortodoncista, quien detecta la impactación del diente, antes de iniciar el tratamiento ortodóncico. Dicho compañero nos indica que, si es posible, no extraigamos el germen del tercer molar, pues prevé que será viable su erupción en el futuro (dispondrá de espacio en la arcada suficiente). Medidos los espacios de que disponemos, decidimos intentar la reubicación del diente impactado sin extraer el germen del cordal, que se llevó a cabo de forma exitosa. Abstract in english The impaction of lower second molars, given that its incidence is 0.03 to 0.21%, is a rare complication in tooth eruption. It has been detected more often in unilateral form than bilateral and is more common in the mandible than in the maxillary. It has a slight predilection for males, and mesial in [...] clination is more usual. A wide variety of therapeutic approaches have been published, basically referring to surgical techniques, independent or complemented by means of orthodontic technical aids, with the aim of placing the tooth in the correct position, and which are encompassed under the concept of surgical rescue. In cases resolved with repositioning of an impacted tooth, prophylactic root extraction has been proposed as obligatory. We present a case of a 12 and a half year old patient referred to the University of Seville due to non-eruption of the left lower second molar. The patient was referred by her orthodontist, who detected the impaction before starting orthodontic treatment. The orthodontist requested that, if it was possible, we did not extract the root of the third molar, because its eruption would be feasible in the future (there would be sufficient space in the arch). The spaces available were measured and we decided to attempt the repositioning of the impacted tooth without extracting the root of the wisdom tooth, which was carried out successfully.

García Calderón, Manuel; Torres Lagares, Daniel; González Martín, Maribel; Gutiérrez Pérez, José Luis.

399

Semilunar Coronally Repositioned Flap for the Treatment of Gingival Recession with and without Tissue Adhesives: A Pilot Study  

Directory of Open Access Journals (Sweden)

Full Text Available Statement of problem: One of the main goals in periodontal therapy is the correction of recession defects; therefore the efficacy and predictability of the various techniques are important considerations for clinicians.Purpose: The purpose of this pilot study was to compare the outcomes of gingival recession therapy using the semilunar coronally repositioned flap (SCRF alone and in conjunction with a tissue adhesive (EPIGLU.Materials and Methods: Thirty-two anterior and premolar teeth with class I and II Miller gingival recessions were selected and randomly divided into two groups. The test group received SCRF followed by EPIGLU application and the control group was managed with SCRF alone. Clinical parameters measured at baseline and 7, 14, 30 and90 days after surgery included vertical and horizontal recession depths, width of keratinized tissue, probing depth, clinical attachment level, percentage of root coverage,and sensitivity of root surface to air flow.Results: The recession depths decreased significantly in both groups (P<0.05. Three months after surgery, the mean root coverage in the test and control groups was 1.86mm (77.96% and 1.57mm (69.1%, respectively. The width of keratinized tissue along with all the other tested parameters except for probing depth, increased significantly in both groups, during the study period (p<0.05. Sensitivity of root surface to air flow was not observed in either group.Conclusion: The SCRF alone or with EPIGLU is an effective procedure for root coverage in anterior and premolar teeth. The addition of EPIGLU improves the amount of root coverage, especially in relatively shallow defects.

M. Jahangirnezhad

2006-03-01

400

Comparative Study of Root Coverage Using Semilunar Coronally Repositioned Flap with and without Topical Application of Tetracycline Solution  

Directory of Open Access Journals (Sweden)

Full Text Available •Introduction: Treatment of gingival recession has been one of the most important aims of periodontalprocedures and therefore introduction of a predictable technique for covering the denuded roots hasbeen an ideal goal for many years.The purpose of this study was the evaluation of root coverage by ";Semilunar coronally repositionedflap"; technique; and the role of topical application of tetracycline hydrochloride in improvement of theresults.•Methods and Materials: 24 anterior and premolar teeth were selected from 9 patients and dividedrandomly in two ";test and control"; groups. After completion of initial procedure and before operation,some quantitative (Vertical recession, depth of gingival sulcus and width of keratinized gingiva, andqualitative variables (Sensitivity of root surface to air flow and feeling of an unsatisfactory appearanceby the patient oneself were measured.In test group, tetracycline 1% (pH = 2.3 was applied 3 minutes by burnishing method on the surfaceof root, before performance of surgery.The patients were visited at the days 7, 14, 30, and 90 after the operation, and healing of the area andhygiene status were evaluated.•Results: Following statistical analysis, it was concluded that recession depth has been reducedsignificantly in both groups, 1 and 3 months after the operation.• The mean root coverage in test group was 2.29 mm (70.33% coverage, and 2.16 mm (67.33%coverage, 1 and 3 months after surgery, respectively.• Width of keratinized tissue was also increased significantly in both groups.• Among the quantitative variables, only probing depth did not alter during the period of research.• Qualitative variables were also improved significantly in both groups.• Apparently, the application of solution as a ";root conditioning agent"; did not influence the results ofthis study.•Conclusion: In summary, the operation technique may be an appropriate procedure for the coverageof the anterior teeth in maxilla, based on its unique advantages.•Key words: Gingival recession, Root coverage, Semilunar coronally repositioned flap, Topical tetracycline,Root sensitivity, Keratinized gingiva

H Golestaneh

2006-01-01

 
 
 
 
401

49 CFR 572.75 - Lumbar spine, abdomen, and pelvis assembly and test procedure.  

Science.gov (United States)

...2009-10-01 2009-10-01 false Lumbar spine, abdomen, and pelvis assembly and test...6-Year-Old Child § 572.75 Lumbar spine, abdomen, and pelvis assembly and test procedure. (a) Lumbar spine, abdomen, and pelvis assembly....

2009-10-01

402

Sagittal Lumbar Spine Position During Standing, Walking, and Running at Various Gradients  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Context: Motion in the lumbar spine during certain physical activities may exceed tissue homeostasis, leading to low back pain. Previous authors have assessed sagittal motion of the lumbar spine during walking; however, limited attention has been focused on changes in spine position with walking or running on different surface gradients.

Levine, David; Colston, Marisa A.; Whittle, Michael W.; Pharo, Elizabeth C.; Marcellin-little, Denis J.

2007-01-01

403

A non-proteinaceous toxin from the venomous spines of the lionfish Pterois volitans (Linnaeus).  

Science.gov (United States)

The venomous spines of P. volitans contain a non-proteinaceous ichthyotoxin of low molecular weight. This toxin could be isolated only from spines excised from the living fish; the toxin is apparently destroyed following death, as the extracts of the spines of the dead fish were non-toxic. PMID:4024148

Nair, M S; Cheung, P; Leong, I; Ruggieri, G D

1985-01-01

404

Identification and classification of spine vertebrae by automated methods  

Science.gov (United States)

We are currently working toward developing computer-assisted methods for the indexing of a collection of 17,000 digitized x-ray images by biomedical content. These images were collected as part of a nationwide health survey and form a research resource for osteoarthitis and bone morphometry. This task requires the development of algorithms to robustly analyze the x-ray contents for key landmarks, to segment the vertebral bodies, to accurately measure geometric features of the individual vertebrae and inter-vertebral areas, and to classify the spine anatomy into normal or abnormal classes for conditions of interest, including anterior osteophytes and disc space narrowing. Subtasks of this work have been created and divided among collaborators. In this paper, we provide a technical description of the overall task, report on progress made by collaborators, and provide the most recent results of our own research into obtaining first-order location of the spine region of interest by automated methods. We are currently concentrating on images of the cervical spine, but will expand the work to include the lumbar spine as well. Development of successful image processing techniques for computer-assisted indexing of medical image collections is expected to have a significant impact within the medical research and patient care systems.

Long, L. Rodney; Thoma, George R.

2001-07-01

405

Partial block vertebra formation in the cervical spine  

International Nuclear Information System (INIS)

The authors discuss the formation of block vertebrae as a form of disturbed segmentation of the cervical spine and describe their own views. The variable appearances of partial block vertebrae, which are most common at C.2/3, which were seen in a large clinical material (6,000 examinations) are described. (orig.)

1980-01-01

406

The cortical and cerebellar representation of the lumbar spine.  

Science.gov (United States)

Eight decades after Penfield's discovery of the homunculus only sparse evidence exists on the cortical representation of the lumbar spine. The aim of our investigation was the description of the lumbar spine's cortical representation in healthy subjects during the application of measured manual pressure. Twenty participants in the prone position were investigated during functional magnetic resonance imaging (fMRI). An experienced manual therapist applied non-painful, posterior-to-anterior (PA) pressure on three lumbar spinous processes (L1, L3, and L5). The pressure (30 N) was monitored and controlled by sensors. The randomized stimulation protocol consisted of 68 pressure stimuli of 5 s duration. Blood oxygenation level dependent (BOLD) responses were analyzed in relation to the lumbar stimulations. The results demonstrate that controlled PA pressure on the lumbar spine induced significant activation patterns. The major new finding was a strong and consistent activation bilaterally in the somatosensory cortices (S1 and S2). In addition, bilateral activation was located medially in the anterior cerebellum. The activation pattern also included other cortical areas probably related to anticipatory postural adjustments. These revealed stable somatosensory maps of the lumbar spine in healthy subjects can subsequently be used as a baseline to investigate cortical and subcortical reorganization in low back pain patients. Hum Brain Mapp 35:3962-3971, 2014. © 2014 Wiley Periodicals, Inc. PMID:24464423

Boendermaker, Bart; Meier, Michael L; Luechinger, Roger; Humphreys, B Kim; Hotz-Boendermaker, Sabina

2014-08-01

407

Dysphagia Due to Anterior Cervical Spine Osteophyte: A Case Report  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction: Degenerative changes of the cervical spine are more common in elderly, but anterior cervical osteophytes that cause problems in swallowing are rare. The most common cause of this problem is DISH disease (diffuse idiopathic skeletal hyperostosis. Trauma is also suggested as a potential cause in osteophyte formation. Case Report: We report a rare case of anterior cervical osteophyte with problems in swallowing that was caused by cervical spine trauma in a car accident 4 years ago, treated with a cervical collar. Dysphagia was the initial symptom of the disease. Barium swallowing showed a large cervical osteophyte at the C3-C4 level with compression effect on the esophagus. X-ray, CT scan and MRI of the cervical spine confirmed the osteophyte and its correlation with the esophagus. Endoscopic study of esophagus and stomach also ruled out other disorders. Surgical osteophytectomy was performed. Conclusion: Up to now, only two cases of post-traumatic anterior cervical osteophyte have been cited in the literature. In this report, we introduce an unusual case of dysphagia caused by cervical spine trauma.

Hossein Mashhadinezhad

2010-07-01

408

Conversion coefficients for determining organ doses in paediatric spine radiography  

Energy Technology Data Exchange (ETDEWEB)

Knowledge of organ and effective doses achieved during paediatric x-ray examinations is an important prerequisite for assessment of radiation burden to the patient. Conversion coefficients for reconstruction of organ and effective doses from entrance doses for segmental spine radiographs of 0-, 1-, 5-, 10-, 15- and 30-year-old patients are provided regarding the Guidelines of Good Radiographic Technique of the European Commission. Using the personal computer program PCXMC developed by the Finnish Centre for Radiation and Nuclear Safety (Saeteilyturvakeskus STUK), conversion coefficients for conventional segmental spine radiographs were calculated performing Monte Carlo simulations in mathematical hermaphrodite phantom models describing patients of different ages. The clinical variation of beam collimation was taken into consideration by defining optimal and suboptimal radiation field settings. Conversion coefficients for the reconstruction of organ doses in about 40 organs and tissues from measured entrance doses during cervical, thoracic and lumbar spine radiographs of 0-, 1-, 5-, 10-, 15- and 30-year-old patients were calculated for the standard sagittal and lateral beam projections and the standard focus detector distance of 115 cm. The conversion coefficients presented may be used for organ dose assessments from entrance doses measured during spine radiographs of patients of all age groups and all field settings within the optimal and suboptimal standard field settings. (orig.)

Seidenbusch, Michael; Schneider, Karl [Ludwig-Maximilians-University of Munich, Institute of Clinical Radiology - Paediatric Radiology, Muenchen (Germany)

2014-04-15

409

Positional device for cinematographic MR of the cervical spine  

International Nuclear Information System (INIS)

A novel positioning device is explained and the experience obtained so far with its application in cinematic MRI of the cervical spine, allowing an extended range of movement from 60 degrees ante- to 40 degrees retroflexion. The tests were done with volounteers. (orig./MG)

1995-03-01

410

Osteoid osteoma in the spine: CT and MR findings  

International Nuclear Information System (INIS)

We present an osteoid osteoma in the spine, which had atypical clinical findings and we report the commuted tomography (CT) and magnetic resonance (MR) findings. MR imaging demonstrated a large area with abnormal signal intensity, characterized by low signal intensity on T1-weighted images and high signal intensity on T2-weighted images, probably due to perinidal bone marrow edema

1993-01-01

411

Reconstitution of lost cervical spine function: management strategies  

Directory of Open Access Journals (Sweden)

Full Text Available The cervical spine (CS is the most vulnerable part of the whole spine because it has least protection. This is due to its high mobility (few bone, but largely muscle and joint support which is associated with a high injury risk. The anatomical characteristics are based on evolutionary biological reasons, i.e. humans had to be able to freely controlling the surrounding space with their eyes and to have permanent postural control by an upright position of the head. The cervical spine, its joint and the surrounding muscles are highly interconnected (e.g. direct neuronal projections into the brain stem, connections to the TMJ, Head's zones with projections to the skin surface. Moreover, the spinal pain memory store can lead to a variets of multi-facette clinical pictures. In addition to reversible disorders of the cervical spine, posttraumatic disorders play a major role. The therapy options available include physiotherapy, drug therapy and surgical measures. However, a multidisciplinary approach is most favourable.

Ernst, Arne

2005-09-01

412

Plasma cellular osteomyelitis of the thoracic spine - a case report  

International Nuclear Information System (INIS)

The authors report the case of a young patient suffering from plasmacellular osteomyelitis of the thoracic spine, an unusual localisation of this type of chronic osteomyelitis. They discuss the role of imaging diagnostic modalities in this disease, focussing on MRI. (orig.)

2000-06-01

413

Complex radiodiagnosis of the lumbar spine spinal canal stenosis  

International Nuclear Information System (INIS)

Ultrasound study was done in 67 patients with osteochondrosis of the lumbar spine revealed by x-ray study, magnetic resonance imaging and computed tomography. Ultrasound technique is highly informative in visualizing location, direction, size of the hernia in lumbar osteochondrosis and stenosis of spinal canal

2006-01-01

414

Conversion coefficients for determining organ doses in paediatric spine radiography  

International Nuclear Information System (INIS)

Knowledge of organ and effective doses achieved during paediatric x-ray examinations is an important prerequisite for assessment of radiation burden to the patient. Conversion coefficients for reconstruction of organ and effective doses from entrance doses for segmental spine radiographs of 0-, 1-, 5-, 10-, 15- and 30-year-old patients are provided regarding the Guidelines of Good Radiographic Technique of the European Commission. Using the personal computer program PCXMC developed by the Finnish Centre for Radiation and Nuclear Safety (Saeteilyturvakeskus STUK), conversion coefficients for conventional segmental spine radiographs were calculated performing Monte Carlo simulations in mathematical hermaphrodite phantom models describing patients of different ages. The clinical variation of beam collimation was taken into consideration by defining optimal and suboptimal radiation field settings. Conversion coefficients for the reconstruction of organ doses in about 40 organs and tissues from measured entrance doses during cervical, thoracic and lumbar spine radiographs of 0-, 1-, 5-, 10-, 15- and 30-year-old patients were calculated for the standard sagittal and lateral beam projections and the standard focus detector distance of 115 cm. The conversion coefficients presented may be used for organ dose assessments from entrance doses measured during spine radiographs of patients of all age groups and all field settings within the optimal and suboptimal standard field settings. (orig.)

2014-04-01

415

Internal fixation for stress fractures of the ankylosed spine.  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Three cases of stress fractures affecting the rigid spine of ankylosing spondylitis are reported. Even without the typical destructive features of the Romanus lesion, symptoms may be very prolonged and disabling and the diagnosis difficult. Internal fixation produces immediate pain relief and rapid fracture union.

Marsh, C. H.

1985-01-01

416

Spine growth mechanisms: friction and seismicity at Mt. Unzen, Japan  

Science.gov (United States)

The final episode of dome growth during the 1991-1995 eruption of Mt. Unzen was characterised by spine extrusion accompanied by repetitive seismicity. This type of cyclic activity has been observed at several dome-building volcanoes and recent work suggests a source mechanism of brittle failure of magma in the conduit. Spine growth may proceed by densification and closure of permeable pathways within the uppermost conduit magma, leading to sealing of the dome and inflation of the edifice. Amplified stresses on the wall rock and plug cause brittle failure near the conduit wall once static friction forces are overcome, and during spine growth these fractures may propagate to the dome surface. The preservation of these features is rare, and the conduit is typically inaccessible; therefore spines, the extruded manifestation of upper conduit material, provide the op