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Hearing Loss  

Medline Plus

Full Text Available Hearing Loss Introduction Hearing problems are pretty common in older people. Around one in three people over the age of 65 have hearing loss. Most people can have very good hearing with ...

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Hearing Loss  

Medline Plus

Full Text Available Hearing Loss Introduction Hearing problems are pretty common in older people. Around one in three people over the ... reference summary will help you better understand hearing loss. Anatomy & Hearing Auricle Ear Canal Tympanic Membrane Ossicles Inner Ear ...

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Hearing Loss  

Medline Plus

Full Text Available ... gotten smaller and better because of technology. This reference summary will help you better understand hearing loss. ... with hearing problems enjoy television programs and movies. Services are also available for people with severe hearing ...

4

Hearing Loss  

Medline Plus

Full Text Available Hearing Loss Introduction Hearing problems are pretty common in older people. Around one in three people over the age of 65 have hearing loss. Most ... for balance. This is why many times hearing problems and balance problems happen together. The fact that ...

5

Hearing Loss  

Medline Plus

Full Text Available ... the sound came from. Causes Hearing loss can result from a variety of problems. Some problems are ... families. Tumors that involve the eighth nerve may result in hearing loss. The most common tumors that ...

6

Hearing Loss  

Medline Plus

Full Text Available ... places. For patients with severe hearing loss, learning sign language can be very helpful and worthwhile. Patients undergoing ... where deafness may result are encouraged to learn sign language while they are still able to hear. Summary ...

7

Hearing Loss  

Medline Plus

Full Text Available ... of the middle ear can also lead to damage of the ossicles. Hearing loss and sometimes deafness ... etc. Some medications can either reversibly or irreversibly damage hearing. You should tell your doctor about all ...

8

Hearing Loss  

Medline Plus

Full Text Available ... hearing loss. Anatomy & Hearing Auricle Ear Canal Tympanic Membrane Ossicles Inner Ear Our ears are very specialized ... inside the ear to the eardrum, or tympanic membrane. 2. The middle ear, which is formed of ...

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Hearing Loss  

Medline Plus

Full Text Available ... For patients with severe hearing loss, learning sign language can be very helpful and worthwhile. Patients undergoing ... deafness may result are encouraged to learn sign language while they are still able to hear. Summary ...

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Hearing Loss  

Medline Plus

Full Text Available ... is known as tinnitus. Diagnosis The diagnosis of hearing loss and its cause starts with a detailed medical history and physical ... 06/21/2011 3 Treatment The treatment of hearing loss depends on its cause. Infections may be treated with antibiotics. Perforated tympanic ...

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Hearing Loss  

Medline Plus

Full Text Available ... 3. The inner ear. Cartilage covered with skin forms the auricle. Unlike bone, ear cartilage may continue ... loss can result in the affected ear. Some forms of hearing loss or deafness are related to ...

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Hearing Loss  

Medline Plus

Full Text Available ... some places. For patients with severe hearing loss, learning sign language can be very helpful and worthwhile. ... for your specific condition. ©1995-2011, The Patient Education Institute, Inc. www.X-Plain.com ol010204 Last ...

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Genetics of Hearing Loss  

Science.gov (United States)

... Center Homepage Share Compartir Genetics of Hearing Loss Hearing loss has many causes. 50% to 60% of hearing loss in babies ... number of things in the environment that can cause hearing loss. 25% or more of hearing loss in babies ...

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What's Hearing Loss?  

Science.gov (United States)

... loss and is more difficult to treat. What Causes Hearing Loss? Hearing loss can happen because a person was ... kids have had ear infections, which also can cause hearing loss. Permanent hearing loss is rare from an ear ...

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Hearing Loss  

Medline Plus

Full Text Available ... com ol010204 Last reviewed: 06/21/2011 3 Treatment The treatment of hearing loss depends on its cause. Infections ... healthcare professional or a recommendation for any particular treatment plan. Like any printed material, it may become ...

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Hereditary Hearing Loss.  

Science.gov (United States)

This article discusses inheritance patterns in hearing loss, epidemiology, clues to genetic causes, locating genes that cause hereditary disorders, genes related to hearing loss disorders in individuals with Usher syndrome, Waardenburg syndrome, Treacher-Collins syndrome, Branchio-oto-renal and Pendred syndromes, and the significance of finding…

Tran, LenhAnh P.; Grundfast, Kenneth M.

1997-01-01

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Hearing Loss  

Medline Plus

Full Text Available ... aids do not work, implantable hearing aids and cochlear implants may be helpful. Implantable hearing aids and cochlear implants transmit sound waves directly to the 8th nerve ...

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OI Issues: Hearing Loss  

Science.gov (United States)

... two main types of hearing loss: conductive and sensorineural. Both types of hearing loss can occur with ... family just as much as between unrelated people. Sensorineural hearing loss tends to be more frequent as ...

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Hearing Loss  

Medline Plus

Full Text Available ... for your specific condition. ©1995-2011, The Patient Education Institute, Inc. ... up and cleaned. This is done using a small special probe and an otoscope or a microscope. Hearing ...

20

Hearing Loss  

Medline Plus

Full Text Available ... for your specific condition. ©1995-2011, The Patient Education Institute, Inc. ... balance. This is why many times hearing problems and balance problems happen together. The fact that ...

 
 
 
 
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Hearing Loss  

Medline Plus

Full Text Available ... may continue to grow throughout life, which is why older people usually have bigger ears than younger ... brain that is responsible for balance. This is why many times hearing problems and balance problems happen ...

22

Hearing Loss  

Medline Plus

Full Text Available ... allow us to hear and to keep our balance. Each ear has three sections: 1. The outer ... part of the inner ear is responsible for balance. The eighth nerve also carries information to the ...

23

Hearing Loss  

Medline Plus

Full Text Available ... to make sounds louder and cut down on background noises. Some hearing aids fit inside the external ... for your specific condition. ©1995-2013, The Patient Education Institute, Inc. www.X-Plain.com ol010205 Last ...

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Hearing Loss  

Medline Plus

Full Text Available ... www.X-Plain.com ol010205 Last reviewed: 05/25/2013 1 Another part of the inner ear ... www.X-Plain.com ol010205 Last reviewed: 05/25/2013 2 The most common cause of hearing ...

25

Noise and Hearing Loss Prevention  

Science.gov (United States)

... and Hearing Loss on the NIOSH Science Blog Smartphone Sound Apps Music-induced Hearing Loss Noise in stock car racing Crowd noise at the World Cup Workplace hearing loss Indoor firing ranges Quick fit hearing ...

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Sudden sensorineural hearing loss.  

Science.gov (United States)

Sudden onset sensorineural hearing loss is a medical emergency that continues to be poorly understood despite being recognized in the literature since 1944 (De Kleyn, 1944). A commonly used criterion to qualify for this diagnosis is a sensorineural hearing loss over three contiguous pure-tone frequencies of 30 dB or more that develops within 72 hours. The vast majority of cases are unilateral and the estimated annual incidence is 20 per 100 000 persons (Nosrati-Zarenoe et al, 2007). A cause for the hearing loss is only identified in up to 10% of cases but 50% of patients will improve spontaneously (Penido et al, 2009). PMID:22504750

Stew, B T; Fishpool, S J C; Williams, H

2012-02-01

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Fluctuant hearing loss  

Digital Repository Infrastructure Vision for European Research (DRIVER)

122 cases of fluctuant hearing loss were studied. Serous otitis media was commonest followed by Meniere’s disease, Acoustic neuroma, fistula of round and oval window, oto-mandibular syndrome, Congenital cholesteatoma and maxillary sinusitis. Cases of Arachnoid cyst, Multiple sclerosis, abnormalities of base of skull and craniocervical region and cervical rib causing fluctuant hearing loss could not be detected. Aetio pathophysiology of all discussed.

Jaiswal, S. K.

1997-01-01

28

Congenital sensorineural hearing loss  

International Nuclear Information System (INIS)

The ears of 47 selected patients with congenital sensorineural hearing loss were examined with complex-motion tomography. The patients were divided into 3 general categories: those with a recognized syndrome, those with sensorineural hearing loss unrelated to any known syndrome, and those with microtia. A great variety of inner ear anomalies was detected, but rarely were these characteristic of a particular clinical entity. The most common finding was the Mondini malformation or one of its variants. Isolated dysplasia of the internal auditory canal or the vestibular aqueduct may be responsible for sensorineural hearing loss in some patients. Patients with microtia may also have severe inner ear abnormalities despite the fact that the outer and inner ears develop embryologically from completely separate systems

1984-01-01

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Experimental autoimmune hearing loss  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Understanding of autoimmune sensorineural hearing loss (ASNHL) has been hindered by the inaccessibility of the inner ear to biopsy and the lack of workable animal models. A report in this issue of the JCI describes a mouse model of CD4+ T cell–mediated ASNHL induced by immunization with peptides from the inner ear–specific proteins cochlin and ?-tectorin.

Billings, Peter

2004-01-01

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Sensorineural hearing loss in children.  

LENUS (Irish Health Repository)

The objective of the study was to examine the aetiology of sensorineural hearing loss (SNHL) in a paediatric population presenting to the National Centre of Medical Genetics. A retrospective chart review from 1998 to 2006. One hundred and twenty nine children were investigated for SNHL. The average age of diagnosis of hearing loss was 36 months. The degree of hearing loss was mild in 8 children, moderate in 33 children, severe in 31 children and profound in 57 children. Eighty-five children (66%) were diagnosed with a hereditary hearing loss, 11 (8%) children had an acquired hearing loss and no cause found in 33 (26%) children. This is the first report of the causes of hearing loss in Irish children. The mean age of diagnosis in our cohort is high and emphasises the need for a neonatal screening programme. There remains a number of children for whom the cause of hearing loss remains unknown.

Wormald, R

2010-02-01

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Hearing loss due to mumps.  

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The possibility of mumps was considered in 33 children with profound unilateral sensorineural hearing loss of unknown origin. Fifteen gave a history of mumps, of whom 12 contracted the infection between the last normal and first abnormal hearing tests. Hearing should be tested after mumps infection.

Hall, R.; Richards, H.

1987-01-01

32

Noise-Induced Hearing Loss  

Science.gov (United States)

... hear some environmental sounds and warning signals Identify sources of loud sounds (such as gas-powered lawnmowers, snowmobiles, power tools, gunfire, or music) that can contribute to hearing loss and try to reduce exposure Adopt behaviors to protect their hearing: Avoid or ...

33

Age-related hearing loss  

Science.gov (United States)

... cannot be reversed and may lead to deafness. Hearing loss may cause you to avoid leaving home. Seek help from ... Hearing loss should be checked as soon as possible. This ... wax in the ear or side effects of medicines. Your health care ...

34

Early detection of hearing loss  

Directory of Open Access Journals (Sweden)

Full Text Available The universal newborn hearing screening (UNHS is currently spreading in Germany, as well, even though there can be no talk of a comprehensive establishment. The introduction of UNHS in several federal states such as Hamburg, Hessen, and Schleswig-Holstein can be ascribed to the personal commitment of individual pediatric audiologists. Apart from the procurement of the screening equipment and the training of the staff responsible for the examination of the newborns, the tracking, i.e. the follow-up on children with conspicuous test results, is of utmost importance. This involves significant administration effort and work and is subject to data protection laws that can differ substantially between the various federal states. Among audiologists, there is consensus that within the first three months of a child’s life, a hearing loss must be diagnosed and that between the age of 3 and 6 months, the supply of a hearing aid must have been initiated. For this purpose, screening steps 1 (usually a TEOAE measurement and 2 (AABR testing need to be conducted in the maternity hospital. The follow-up of step 1 then comprises the repetition of the TEOAE- and AABR measurement for conspicuous children by a specialized physician. The follow-up of step 2 comprises the confirmatory diagnostics in a pediatric audiological center. This always implies BERA diagnostics during spontaneous sleep or under sedation. The subsequent early supply of a hearing aid should generally be conducted by a (pediatric acoustician specialized on children.

Schade, Götz

2008-01-01

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Noise-Induced Hearing Loss in Children  

Science.gov (United States)

... hearing loss in children. How does noise exposure cause hearing loss? Very loud sounds damage the inner ear by ... measured at 115 decibels, a level that can cause hearing loss to listeners of all ages. A survey sponsored ...

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Imaging Evaluation of Hearing Loss  

Directory of Open Access Journals (Sweden)

Full Text Available Hearing loss is a common disorder in all societies.Radiologists are often asked to evaluate the complex inner ear structures and auditory pathways in search of a cause for hearing loss. The seemingly complex anatomy of the temporal bone can make some radiologists uncomfortable in interpretation of these studies. In this talk, we will briefly focus on the pertinent imaging anatomy and attempt to go over some of the imaging findings of sensorineural and conductive hearing loss. Optimizing imaging technique will be reviewed. A variety of causes of congenital and acquired causes of hearing loss will be examined, and multiple imaging examples will be presented. Practical tips on how to interpret these studies and how to"nreport them will be given. Imaging is also an important part of the work-up for cochlear implantation. Contraindications, timing, and imaging findings that may necessitate changes in surgical approach will be reviewed.

A. Vossough

2008-01-01

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Devices for hearing loss  

Science.gov (United States)

... bring the sound from your TV, radio, or music player directly to your inner ear. Many listening ... easier to use your hearing aid with a digital phone line. This helps prevent some distortion. Telecommunication ...

38

Living with Hearing Loss  

Science.gov (United States)

... and Cathryn), Nora's hearing impairment meant a re-education on communicating, one that would serve them well when Bob suffered a traumatic brain injury while reporting in Iraq ( See cover story, page 2 ). The NIDCD celebrates ...

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JAMA Patient Page: Adult Hearing Loss  

Science.gov (United States)

... Adult Hearing Loss In-the-canal hearing aid Tympanic membrane (ear drum) Inner ear Middle ear Ear canal ... are sent down the ear canal to the tympanic membrane. The amplified sound can enhance existing hearing to ...

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Risk factors for hearing loss in elderly  

Directory of Open Access Journals (Sweden)

Full Text Available Objective: To identify risk factors related to sensorineural hearing loss in elderly. Methods: The sample consisted of 60 selected elderly, divided into two groups: the Case Group, composed by 30 individuals, 21 females and 9 males, aged at least 60 years, presenting sensorineural hearing loss, and the Control Group, composed by 30 individuals matched on gender and age, with normal hearing. The patients were submitted to audiological anamnesis and tonal audiometry. The hearing impairment was defined according to average threshold greater than 35dBNA, in the frequencies of 1,000; 2,000 and 4,000 Hz, in the best ear. Results: Statistically significant odds ratios were: a to audiological history: noise exposure and family history of deafness; b to situations involving hearing difficulty: television, church, telephone, silent environment, spatial location of sound, difficulty with voices and noisy environment; c to otologic history: tinnitus, otorrhea and nausea; and d to medical history: visual problems, smoke, alcohol, thyroid problems and kidney disease. Conclusion: The findings of this study highlighted, for sensorineural hearing loss, risk factors related to audiologic, otologic and medical history, and to situations involving hearing difficulty.

Kelly Vasconcelos Chaves Martins

2012-06-01

 
 
 
 
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Auditory Memory deficit in Elderly People with Hearing Loss  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction: Hearing loss is one of the most common problems in elderly people. Functional side effects of hearing loss are various. Due to the fact that hearing loss is the common impairment in elderly people; the importance of its possible effects on auditory memory is undeniable. This study aims to focus on the hearing loss effects on auditory memory.   Materials and Methods: Dichotic Auditory Memory Test (DVMT was performed on 47 elderly people, aged 60 to 80; that were divided in two groups, the first group consisted of elderly people with hearing range of 24 normal and the second one consisted of 23 elderly people with bilateral symmetrical ranged from mild to moderate Sensorineural hearing loss in the high frequency due to aging in both genders.   Results: Significant difference was observed in DVMT between elderly people with normal hearing and those with hearing loss (P

Zahra Shahidipour

2013-06-01

42

Noise-induced hearing loss.  

Science.gov (United States)

Noise-induced hearing loss (NIHL) still remains a problem in developed countries, despite reduced occupational noise exposure, strict standards for hearing protection and extensive public health awareness campaigns. Therefore NIHL continues to be the focus of noise research activities. This paper summarizes progress achieved recently in our knowledge of NIHL. It includes papers published between the years 2008-2011 (in English), which were identified by a literature search of accessible medical and other relevant databases. A substantial part of this research has been concerned with the risk of NIHL in the entertainment sector, particularly in professional, orchestral musicians. There are also constant concerns regarding noise exposure and hearing risk in "hard to control" occupations, such as farming and construction work. Although occupational noise has decreased since the early 1980s, the number of young people subject to social noise exposure has tripled. If the exposure limits from the Noise at Work Regulations are applied, discotheque music, rock concerts, as well as music from personal music players are associated with the risk of hearing loss in teenagers and young adults. Several recent research studies have increased the understanding of the pathomechanisms of acoustic trauma, the genetics of NIHL, as well as possible dietary and pharmacologic otoprotection in acoustic trauma. The results of these studies are very promising and offer grounds to expect that targeted therapies might help prevent the loss of sensory hair cells and protect the hearing of noise-exposed individuals. These studies emphasize the need to launch an improved noise exposure policy for hearing protection along with developing more efficient norms of NIHL risk assessment. PMID:23257577

Sliwinska-Kowalska, Mariola; Davis, Adrian

2012-01-01

43

Effects of Hearing Loss on Development  

Science.gov (United States)

... impact. There are four major ways in which hearing loss affects children-- It causes delay in the development of receptive and expressive communication skills (speech and language). The language deficit causes ... who have hearing loss. Children with hearing loss learn concrete words like ...

44

Radiation Therapy and Hearing Loss  

International Nuclear Information System (INIS)

A review of literature on the development of sensorineural hearing loss after high-dose radiation therapy for head-and-neck tumors and stereotactic radiosurgery or fractionated stereotactic radiotherapy for the treatment of vestibular schwannoma is presented. Because of the small volume of the cochlea a dose-volume analysis is not feasible. Instead, the current literature on the effect of the mean dose received by the cochlea and other treatment- and patient-related factors on outcome are evaluated. Based on the data, a specific threshold dose to cochlea for sensorineural hearing loss cannot be determined; therefore, dose-prescription limits are suggested. A standard for evaluating radiation therapy-associated ototoxicity as well as a detailed approach for scoring toxicity is presented.

2010-03-01

45

IDIOPATHIC SUDDEN SENSORINEURAL HEARING LOSS  

Directory of Open Access Journals (Sweden)

Full Text Available Objective: The purpose of this study is to present our patients with ISSHL and to assess the shape of the audiogram and the recovery incidence of the patients.Methods: 28 patients who were referred to our clinic under diagnosis as idiopathic sudden sensorineural hearing loss during two years (between 2004 - 2006 were included in the study. Routine audiological evaluation was performed to all patients. Shape of initial audiograms was classified in 3 groups: (1 flat audiogram; (2 upsloping audiogram; (3 downsloping audiogram. Differences in PTA and WDS between pre and post-treatment were calculated to assess the recovery of hearing.Results: In this study, recovery rate was high in each of the three groups. There was no difference in the recovery rate between the groups. There was no relation between recovery and early referral to therapy. The groups were very small for statistical analysis.Conclusion: It is necessary to enlarge the study group to compare the effects of the factors on idiophatic sudden sensorineural hearing loss.

Ufuk Derinsu

2006-01-01

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Post meningitic sensori-neural hearing loss in children--alterations in hearing level.  

Science.gov (United States)

Post meningitic sensori-neural hearing loss was studied in forty new cases of bacterial meningitis and ten cases of viral meningitis treated at the Pediatric Institute, Kuala Lumpur Hospital from April 1991 to March 1992. Hearing assessment at 2 weeks, 3 months and 6 months following the diagnosis of meningitis using Brain Stem Evoked Response Audiometry showed that hearing loss was prevalent only in patients with bacterial meningitis. Hearing loss was detected in 32.5% of these patients during the acute phase of the disease, 22.8% after 3 months and 24.2% after 6 months. In 63.6% of the affected cases, hearing loss was bilateral. In 61.5% of the patients who had hearing loss during the acute phase of the disease, it was permanent, 16.7% had either partial or complete recovery and, 15.4% had deterioration in hearing level. In 2 cases the subsequent hearing level was unknown. The risk of developing sensori neural hearing loss was found to be significantly higher in patients who developed other neurological sequelae. The study highlights the importance of performing repeated hearing assessment in children with bacterial meningitis and the difficulty in appropriate selection of hearing aids in the early stages. PMID:10968099

Yeat, S W; Mukari, S Z; Said, H; Motilal, R

1997-09-01

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Murine malaria is associated with significant hearing impairment  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Plasmodium falciparum malaria has been suspected to cause hearing loss. Developmental, cognitive and language disorders have been observed in children, surviving cerebral malaria. This prospective study aims to evaluate whether malaria influences hearing in mice. Methods Twenty mice were included in a standardized murine cerebral malaria model. Auditory evoked brainstem responses were assessed before infection and at the peak of the illness. Results A significant hearing impairment could be demonstrated in mice with malaria, especially the cerebral form. The control group did not show any alterations. No therapy was used. Conclusion This suggests that malaria itself leads to a hearing impairment in mice.

Stephan Kurt

2010-06-01

48

Medulloblastoma Manifesting as Sudden Sensorineural Hearing Loss  

Digital Repository Infrastructure Vision for European Research (DRIVER)

We present a rare case of medulloblastoma which presented with unilateral sudden sensorineural hearing loss as an initial symptom. A 19-year-old man was admitted to our hospital with a chief complaint of dizziness and facial numbness on the right side. His illness had begun two years previously with sudden hearing loss on the right side, for which he had been treated as an idiopathic sudden hearing loss. Magnetic resonance imaging demonstrated abnormal signals located mainly in the right midd...

Terakawa, Yuzo; Tsuyuguchi, Naohiro; Takami, Toshihiro; Ohata, Kenji

2011-01-01

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Relation between Glaucoma and Sensorineural Hearing Loss  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction: Glaucoma is one of the leading causes of blindness throughout the world. Some studies have suggested a relationship between glaucoma and sensorineural hearing loss, while others have found no evidence of an association. We performed a study to determine whether there is a significant difference in hearing of patients with glaucoma and a match control population. Methods: In this cross-sectional study, from February, 2005 till April, 2006, 44 patients with glaucoma were studied. The age range was between 15 to 60 years. After taking a complete medical history, those suffering from presbycusis, history of exposure to ototoxic drugs and substances and history of ear surgery were excluded from the study. All of the patients were cases of open-angle glaucoma, and were surveyed separately for normal-pressure glaucoma. Then complete audiometric tests (PTA, SDS, SRT, Impedance were conducted for all of them, and the results compared with a control group. Results: There was no statistically significant difference between the case group and control group in PTA, SDS, and SRT, except for Normal Tension Glaucoma (NTG. There wasn't any statistically significant difference between two groups with respect to age, gender, and history of diseases. In the NTG group, significant difference was seen only in high frequencies. Conclusion: As mentioned, there was a statistically significant difference between NTG group and control group. It is therefore recommended to conduct complete audiometric tests and histopathologic examinations in this group for early detection of hearing loss and application of rehabilitative measures.

A Mollasadeghi

2008-01-01

50

Changes in auditory perceptions and cortex resulting from hearing recovery after extended congenital unilateral hearing loss  

Directory of Open Access Journals (Sweden)

Full Text Available Monaural hearing induces auditory system reorganization. Imbalanced input also degrades time-intensity cues for sound localization and signal segregation for listening in noise. While there have been studies of bilateral auditory deprivation and later hearing restoration (e.g. cochlear implants, less is known about unilateral auditory deprivation and subsequent hearing improvement. We investigated effects of long-term congenital unilateral hearing loss on localization, speech understanding, and cortical organization following hearing recovery. Hearing in the congenitally affected ear of a 41 year old female improved significantly after stapedotomy and reconstruction. Pre-operative hearing threshold levels showed unilateral, mixed, moderately-severe to profound hearing loss. The contralateral ear had hearing threshold levels within normal limits. Testing was completed prior to, and three and nine months after surgery. Measurements were of sound localization with intensity-roved stimuli and speech recognition in various noise conditions. We also evoked magnetic resonance signals with monaural stimulation to the unaffected ear. Activation magnitudes were determined in core, belt, and parabelt auditory cortex regions via an interrupted single event design. Hearing improvement following 40 years of congenital unilateral hearing loss resulted in substantially improved sound localization and speech recognition in noise. Auditory cortex also reorganized. Contralateral auditory cortex responses were increased after hearing recovery and the extent of activated cortex was bilateral, including a greater portion of the posterior superior temporal plane. Thus, prolonged predominant monaural stimulation did not prevent auditory system changes consequent to restored binaural hearing. Results support future research of unilateral auditory deprivation effects and plasticity, with consideration for length of deprivation, age at hearing correction, degree and type of hearing loss.

JillBFirszt

2013-12-01

51

Changes in auditory perceptions and cortex resulting from hearing recovery after extended congenital unilateral hearing loss.  

Science.gov (United States)

Monaural hearing induces auditory system reorganization. Imbalanced input also degrades time-intensity cues for sound localization and signal segregation for listening in noise. While there have been studies of bilateral auditory deprivation and later hearing restoration (e.g., cochlear implants), less is known about unilateral auditory deprivation and subsequent hearing improvement. We investigated effects of long-term congenital unilateral hearing loss on localization, speech understanding, and cortical organization following hearing recovery. Hearing in the congenitally affected ear of a 41 year old female improved significantly after stapedotomy and reconstruction. Pre-operative hearing threshold levels showed unilateral, mixed, moderately-severe to profound hearing loss. The contralateral ear had hearing threshold levels within normal limits. Testing was completed prior to, and 3 and 9 months after surgery. Measurements were of sound localization with intensity-roved stimuli and speech recognition in various noise conditions. We also evoked magnetic resonance signals with monaural stimulation to the unaffected ear. Activation magnitudes were determined in core, belt, and parabelt auditory cortex regions via an interrupted single event design. Hearing improvement following 40 years of congenital unilateral hearing loss resulted in substantially improved sound localization and speech recognition in noise. Auditory cortex also reorganized. Contralateral auditory cortex responses were increased after hearing recovery and the extent of activated cortex was bilateral, including a greater portion of the posterior superior temporal plane. Thus, prolonged predominant monaural stimulation did not prevent auditory system changes consequent to restored binaural hearing. Results support future research of unilateral auditory deprivation effects and plasticity, with consideration for length of deprivation, age at hearing correction and degree and type of hearing loss. PMID:24379761

Firszt, Jill B; Reeder, Ruth M; Holden, Timothy A; Burton, Harold; Chole, Richard A

2013-01-01

52

Beta blockers and loss of hearing.  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Loss of hearing in a 43 year old man during treatment with metoprolol was dose related and disappeared within a few months after the drug had been stopped. The hearing impairment was of mixed type, with an air bone gap without any disorder of the middle ear observable by conventional clinical methods. Similar scattered reports from international sources on loss of hearing during treatment with beta blockers are also presented.

Fa?ldt, R.; Liedholm, H.; Aursnes, J.

1984-01-01

53

Sudden (reversible) sensorineural hearing loss in pregnancy.  

LENUS (Irish Health Repository)

Sudden hearing loss directly associated with pregnancy or birth is a little known and rare occurrence. The temporary, unilateral, low-frequency sensorineural hearing loss in this case was reported after the birth of the patient\\'s first child, and again during the third trimester of her second pregnancy.

Kenny, R

2011-03-01

54

Hearing Loss and Older Adults  

Science.gov (United States)

... lee-ur) implants are small electronic devices surgically implanted in the inner ear that help provide a ... hearing aids described above, implantable hearing aids are designed to help increase the transmission of sound vibrations ...

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The significance of a hypoplastic bony canal for the cochlear nerve in patients with sensorineural hearing loss: CT and MRI findings  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this study is to evaluate the significance of the hypoplastic canal for the cochlear nerve in patients with sensorineural hearing loss (SNHL) and the relationship between the hypoplastic bony canal and aplasia or hypoplasia of the cochlear nerve. A retrospective review of high resolution temporal CT(HRCT) and MRI findings was conducted. The narrow bony canal of the cochlear nerve and the relative size of the internal auditory canal were correlated with the cochlear nerve deficiency on MRI. The comparative size of the component nerves (facial, cochlear, superior vestibular, inferior vestibular nerve), and the relative size of the internal auditory canal and the bony canal of the cochlear nerve were measured. The clinical history and the results of the clinical examination were reviewed for each patient. High resolution MRI showed aplasia of the common vestibulocochlear nerve in one patient and a deficiency of the cochlear nerve in 9 patients. These abnormalities occurred in association with a prominent narrowing of the canal for the cochlear nerve and a stenosis of the internal auditory canal, which was observed on temporal bone CT in 9 patients with congenital SNHL. Three patients had normal IAC, despite the presence of a hypoplastic cochlear nerve on the side on which they had SNHL. In one patient, the narrowing of the canal for the cochlear nerve and internal auditory canal were not found to be associated with acquired SNHL. The hypoplastic bony canal for the cochlear nerve might be more highly indicative of congenital cochlear nerve deficiency than that of the narrow internal auditory canal, and the position of the crista falciformis should also be carefully.

Choi, Yoon Jung; Park, Sang Yoo; Kim, Myung Soon; Sung, Ki Jun [College of Medicine, Yonsei Univ., Wonju (Korea, Republic of)

2004-04-01

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The significance of a hypoplastic bony canal for the cochlear nerve in patients with sensorineural hearing loss: CT and MRI findings  

International Nuclear Information System (INIS)

The purpose of this study is to evaluate the significance of the hypoplastic canal for the cochlear nerve in patients with sensorineural hearing loss (SNHL) and the relationship between the hypoplastic bony canal and aplasia or hypoplasia of the cochlear nerve. A retrospective review of high resolution temporal CT(HRCT) and MRI findings was conducted. The narrow bony canal of the cochlear nerve and the relative size of the internal auditory canal were correlated with the cochlear nerve deficiency on MRI. The comparative size of the component nerves (facial, cochlear, superior vestibular, inferior vestibular nerve), and the relative size of the internal auditory canal and the bony canal of the cochlear nerve were measured. The clinical history and the results of the clinical examination were reviewed for each patient. High resolution MRI showed aplasia of the common vestibulocochlear nerve in one patient and a deficiency of the cochlear nerve in 9 patients. These abnormalities occurred in association with a prominent narrowing of the canal for the cochlear nerve and a stenosis of the internal auditory canal, which was observed on temporal bone CT in 9 patients with congenital SNHL. Three patients had normal IAC, despite the presence of a hypoplastic cochlear nerve on the side on which they had SNHL. In one patient, the narrowing of the canal for the cochlear nerve and internal auditory canal were not found to be associated with acquired SNHL. The hypoplastic bony canal for the cochlear nerve might be more highly indicative of congenital cochlear nerve deficiency than that of the narrow internal auditory canal, and the position of the crista falciformis should also be carefully

2004-04-01

57

Sound preconditioning therapy inhibits ototoxic hearing loss in mice  

Science.gov (United States)

Therapeutic drugs with ototoxic side effects cause significant hearing loss for thousands of patients annually. Two major classes of ototoxic drugs are cisplatin and the aminoglycoside antibiotics, both of which are toxic to mechanosensory hair cells, the receptor cells of the inner ear. A critical need exists for therapies that protect the inner ear without inhibiting the therapeutic efficacy of these drugs. The induction of heat shock proteins (HSPs) inhibits both aminoglycoside- and cisplatin-induced hair cell death and hearing loss. We hypothesized that exposure to sound that is titrated to stress the inner ear without causing permanent damage would induce HSPs in the cochlea and inhibit ototoxic drug–induced hearing loss. We developed a sound exposure protocol that induces HSPs without causing permanent hearing loss. We used this protocol in conjunction with a newly developed mouse model of cisplatin ototoxicity and found that preconditioning mouse inner ears with sound has a robust protective effect against cisplatin-induced hearing loss and hair cell death. Sound therapy also provided protection against aminoglycoside-induced hearing loss. These data indicate that sound preconditioning protects against both classes of ototoxic drugs, and they suggest that sound therapy holds promise for preventing hearing loss in patients receiving these drugs.

Roy, Soumen; Ryals, Matthew M.; Van den Bruele, Astrid Botty; Fitzgerald, Tracy S.; Cunningham, Lisa L.

2013-01-01

58

SELF REPORTED HEARING LOSS AMONG ELDERLY MALAYSIANS  

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Full Text Available A cross-sectional study was conducted on patients attending a primary care facility to determine the prevalence of self reported hearing loss using a single question, “Do you have hearing loss?” Pure tone audiometry was performed to compare the accuracy of the self report. A total of 111 patients were recruited. The prevalence of self reported hearing loss using a single question and pure tone audiometry was 24.3% and 36.9% respectively. By using pure tone audiometry at a cut-off-level of 25 dBHL (decibels Hearing level, the single question yielded a sensitivity of 41.4% and specificity of 85.0%. The single question performed better at 40 dBHL pure tone audiometry with sensitivity of 55.0% and specificity of 82.0%. In conclusion, the prevalence of hearing loss in elderly was high and the single question self reported hearing loss performed satisfactorily with moderate hearing loss.

MAJMIN SH

2010-01-01

59

Hearing Loss Might Make Elderly Feel More Isolated  

Science.gov (United States)

... JavaScript. Hearing Loss Might Make Elderly Feel More Isolated Study found those who had trouble hearing became ... with hearing loss may become even more socially isolated, according to a new study. Researchers in Sweden ...

60

Gd enhanced MRI in sensorineural hearing loss  

International Nuclear Information System (INIS)

The enhanced MRI hearing findings of the inner ear in 124 patients with sensorineural hearing loss were evaluated. MR images were obtained before and after the intravenous administration of gadolinium (0.1 mmol/kg). In three out of seventy-nine patients with unilateral healing loss, cochlear and/or the vestibular enhancement was noted on the symptomatic side. The positive cases included those with Ramsay-Hunt syndrome, mumps and so-called sudden deafness. Forty-five patients with bilateral hearing loss showed no enhancement within the inner ear. Although positive gadolinium enhancement of the inner ear may detect inflammatory lesions due to a viral infection, its incidence in sensorineural hearing loss, including cases of sudden deafness. seems to be extremely rare. (author)

1996-09-01

 
 
 
 
61

Assessment of Hearing Loss by OAE in Asphyxiated Newborns  

Science.gov (United States)

Background: Severe birth asphyxia (apgar < 7 at the 5th minute of birth) is recognized as a hearing loss risk factor by the joint committee on infant hearing (JCIH). About half of the newborns with hearing loss do not indicate any sign and risk factor at birth. Accordingly, the joint committee recommended performance of hearing screening test in 2000, especially for babies born with risk factors. Objectives: The aim of this study was to evaluate hearing loss in asphyxiated neonates. Early diagnosis would result in early treatment of these newborns. Patients and Methods: We assessed the relationship between asphyxia and hearing impairment in newborns admitted to a referral hospital, Tehran, Iran within 3 years (2003 - 2006). Hearing problems were diagnosed and followed by otoacoustic emission (OAE) in the third and fifth days of birth. Asphyxiated neonates with abnormal OAE were referred to an ENT specialist; second OAE and tympanometry were carried out after 2 weeks. Based on the results, newborns underwent treatment or were discharged. Results: Of 149 asphyxiated neonates, 80 had mean first minute apgar score of 4.01, and mean 5th minute score was 7.24. Two percent (3/149) of asphyxiated neonates had abnormal OAEs. No statistical correlation was found between the 5th minute apgar score and abnormal OAE (P value = 0.391). However, a significant relationship between the mean birth weight and abnormal OAE (P value = 0.0406) was found. Conclusions: It seems that birth asphyxia is not correlated with hearing loss.

Amini, Elaheh; Kasheh Farahani, Zahra; Rafiee Samani, Mehdi; Hamedi, Hamed; Zamani, Ali; Karimi Yazdi, Alireza; Nayeri, Fatemeh; Nili, Firoozeh; Rezaeizadeh, Golnaz

2014-01-01

62

Sensorineural Hearing Loss in Chronic Otitis Media  

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Full Text Available Introduction: Conductive hearing loss due to chronic otitis media (COM can be treated by surgery. COM, however, may be associated with functional damage to the inner ear. Sensorineural hearing loss (SNHL due to COM has been found to be significant by some authors, whereas it has been considered negligible by others. The present study aimed to answer the question; Does COM cause SNHL ? Methods: 120 patients with unilateral COM admitted for tympano-mastoidectomy were selected for this observational case-control study. Air conduction threshold (ACT and bone conduction threshold (BCT averages were calculated at the speech frequencies (500, 1000, 2000Hz and 4 KHz, in affected (case ear and non affected (control ear and then entered in the questionnaire along with intraoperative findings. Multiple statistical tests were used to clarify the relationships between SNHL and COM. Results: COM was seen to be associated with SNHL. The Threshold shift was more accentuated at 4 KHz in older patients. SNHL at 4 KHz seemed to be higher than that at the speech frequencies. There was a significant positive relationship between the elevated BCT and duration of COM. The relationship between elevated BCT and cholesteatoma was also significant. Conclusion: The inner ear is vulnerable to COM. The proximity of the sensory cells to the potential source of harm (inflamed middle ear may mean higher exposure, as reflected by the fact that sensory cells processing high frequencies are more seriously damaged. SNHL in affected ear is strongly dependant on duration of disease.

R Jafari

2008-01-01

63

Sudden sensorineural hearing loss: An update  

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For many otolaryngologists the management of acute sensorineural hearing loss is an intuitive exercise. The ideas that govern a practice is as important as treating the patients and preventing progression of the disease; this has evolved by retrospective, anecdotal reports and clinical experience rather than through prospective research. To evaluate the current literature on management of such sensorineural hearing loss, a medline search of the topic was carried out and evidence based on rece...

1997-01-01

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Sudden Sensorineural Hearing Loss: An Otologic Emergency  

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The study purpose was to determine the efficacy of steroids, volume expanders and antivirals in the management of idiopathic sudden sensory neural hearing loss and to establish importance of early medical intervention. In this prospective study, thirty-four patients presenting with idiopathic sudden hearing loss of 30 db or more were enrolled in study group between 2005 and 2009. Patient variables as they related to recovery were studied and include patient age, time to onset of therapy, sta...

Vijayendra, H.; Buggaveeti, Greeshma; Parikh, Bhavin; Sangitha, R.

2012-01-01

65

Unilateral Hearing Loss in Children  

Science.gov (United States)

... environment while your child is watching TV, doing homework, or playing with others. Do not give your ... option for your child. Some children with UHL benefit from using a hearing aid. Factors to consider ...

66

Gender effects in hearing loss in Dalmatians.  

Science.gov (United States)

Brainstem auditory-evoked-response data were collected from 3101 Dalmatian dogs from 1984 to 1998 at the Veterinary Medicine Teaching Hospital at the University of California, Davis. Also collected were data on eye color and the presence or absence of a color-patch at birth. Our objective was to evaluate the role of gender in hearing loss, including the possibility that the probability of suffering unilateral or bilateral deafness was greater if the dam was hearing impaired than if the sire was hearing impaired. Results of a multiple-trait threshold-model analysis support the commonly held observation that females were more likely to be deaf than males. In addition, females were also more likely to have two blue eyes (a condition associated with an increased prevalence of deafness). However, gender differences in hearing loss were limited to these direct observations. There was no detectable difference in the prevalence of hearing loss between offspring of deaf mothers and the offspring of deaf fathers. Finally, there was no detectable decrease in the prevalence of hearing loss over the years covered in the data set - suggesting that Dalmatian breeders are not yet selecting against hearing problems. PMID:11150631

Famula, T R; Oberbauer, A M; Williams, D C

2001-01-17

67

Hearing and hearing loss: Causes, effects, and treatments  

Science.gov (United States)

Hearing loss can have multiple causes. The outer and middle ears are conductive pathways for acoustic energy to the inner ear (cochlea) and help shape our spectral sensitivity. Conductive hearing loss is mechanical in nature such that the energy transfer to the cochlea is impeded, often from eardrum perforations or middle ear fluid buildup. Beyond the middle ear, the cochlea comprises three interdependent systems necessary for normal hearing. The first is that of basilar-membrane micromechanics including the outer hair cells. This system forms the basis of the cochlear amplifier and is the most vulnerable to noise and drug exposure. The second system comprises the ion pumps in the lateral wall tissues of the cochlea. These highly metabolic cells provide energy to the cochlear amplifier in the form of electrochemical potentials. This second system is particularly vulnerable to the effects of aging. The third system comprises the inner hair cells and their associated sensory nerve fibers. This system is the transduction stage, changing mechanical vibrations to nerve impulses. New treatments for hearing loss are on the horizon; however, at present the best strategy is avoidance of cochlear trauma and the proper use of hearing aids. [Work supported by NIA and MUSC.

Schmiedt, Richard A.

2003-04-01

68

Experiences of adult patients hearing loss postlingually with Cochlear Implant  

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Full Text Available Hearing loss is a significant public health problem. The incidence is difficult to establish because of the lack of data in people under age three, but is estimated about 1 per thousand for severe and profound hearing loss.A cochlear implant (CI is a device that converts sounds into electrical energy that triggers a sensation of hearing. The IC is indicated in patients with severe bilateral sensorineural hearing loss with null or poor benefit use of hearing aids.The general objective of this project is to understand the experiences of adult patients with severe-profound sensorineural hearing loss with IC postlingually throughout the implementation process.A personal vision of those implemented will allow us to learn how to face the possibility to hear and interact with their environment, applying this information to improve health care provided to them and identifying those areas where such assistance should be improved. Also allow us to compare the initial expectations and have been achieved, creating realistic expectations for future candidates.For its development we have designed a qualitative study, based on the principles and procedures of grounded theory, semistructured interviews, participant observation and discussion groups.The data will be analyzed using the software Nudist ViVo 9.

Teresa María Lizcano Tejado

2013-09-01

69

Hearing Loss in Patients with Systemic Lupus Erythematosus  

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Full Text Available Objectives: Systemic lupus erythematosus has its unique complications which warrant careful examination and assessment during follow/up visits of patients. The present study was conducted to evaluate prevalence of hearing loss in patients with SLE. Materials & Methods: At present a case- control study has been performed on 45 patients with SLE in a clinic of a teaching university hospital, Qazvin city, Iran. The patients were examined and evaluated for auditory and hearing problems as well as parameters related to their disease severity and progression. The control group was selected from the same clinic. Results: Five patients (11.1% complained from hearing loss, 4 patients s (8.9% complained from otorrhea, 3 patients (6.7% had tinnitus in research group, moreover twelve patients (26.7% in case group and 4 patients (8.9% in control group had sensorineural hearing loss. The difference was found to be statistically significant. No statistical significant relationship was found between severity, age of onset, and duration of the disease, and the lab tests of the patients with hearing loss. Conclusion: The present study implies that patients with systemic lupus erythematosus may develop sensorineural hearing loss during their course of the disease. It is recommended that audiology examination and/or audiometry become a part of routine follow/up studies of the patients.

Zahra Zarin Bakhsh

2013-05-01

70

Correlating the site of tympanic membrane perforation with Hearing loss  

Science.gov (United States)

Background It is recognized that the size of tympanic membrane(TM) perforation is proportional to the magnitude of hearing loss, however, there is no clear consensus on the effect of the location (site) of the perforation on the hearing loss. Hence the study is set to investigate the relationship between the location of perforation on TM and hearing loss. Methods A cross-sectional prospective study of consecutive adult patients with perforated TM conducted in the ENT clinic of University College Hospital Ibadan between January 1st 2005 and July 31st 2006. Instruments used for data collection/processing include questionnaires, video and micro-otoscopy, Pure tone audiometer, image J and SPSS packages. Results Sixty-two patients (22-males, 40-females), aged 16–75 years (mean = 35.4 +/- 4) with 77 perforated ear drums were studied and 15(24.2%) had bilateral TM perforations, 21 (33.9%) right unilateral and 26(41.9%) left unilateral. The locations of the TM perforations were 60(77.9%) central, 6(9.6%) antero-inferior, 4(5.2%) postero-inferior, 4(5.2%) antero-superior and 3(3.9%) postero-superior respectively with sizes ranging from 1.51%–89.05%, and corresponding hearing levels 30 dB – 80 dB (59% conductive and 41% mixed). Fifty-nine percent had pure conductive hearing loss and the rest mixed. Hearing losses (dBHL) increased with the size of perforations (P = 0.01, r = 0.05). Correlation of location of perforations with magnitude of hearing loss in acute TM perorations was (P = 0.244, r = 0.273) and for chronic perforations (p = 0.047 & r = 0.31). Conclusion The location of perforation on the tympanic membrane (TM) has no effect on the magnitude of hearing loss in acute TM perforations while it is significant in chronic ones.

Ibekwe, Titus S; Nwaorgu, Onyekwere G; Ijaduola, Taiwo G

2009-01-01

71

Correlating the site of tympanic membrane perforation with Hearing loss  

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Full Text Available Abstract Background It is recognized that the size of tympanic membrane(TM perforation is proportional to the magnitude of hearing loss, however, there is no clear consensus on the effect of the location (site of the perforation on the hearing loss. Hence the study is set to investigate the relationship between the location of perforation on TM and hearing loss. Methods A cross-sectional prospective study of consecutive adult patients with perforated TM conducted in the ENT clinic of University College Hospital Ibadan between January 1st 2005 and July 31st 2006. Instruments used for data collection/processing include questionnaires, video and micro-otoscopy, Pure tone audiometer, image J and SPSS packages. Results Sixty-two patients (22-males, 40-females, aged 16–75 years (mean = 35.4 +/- 4 with 77 perforated ear drums were studied and 15(24.2% had bilateral TM perforations, 21 (33.9% right unilateral and 26(41.9% left unilateral. The locations of the TM perforations were 60(77.9% central, 6(9.6% antero-inferior, 4(5.2% postero-inferior, 4(5.2% antero-superior and 3(3.9% postero-superior respectively with sizes ranging from 1.51%–89.05%, and corresponding hearing levels 30 dB – 80 dB (59% conductive and 41% mixed. Fifty-nine percent had pure conductive hearing loss and the rest mixed. Hearing losses (dBHL increased with the size of perforations (P = 0.01, r = 0.05. Correlation of location of perforations with magnitude of hearing loss in acute TM perorations was (P = 0.244, r = 0.273 and for chronic perforations (p = 0.047 & r = 0.31. Conclusion The location of perforation on the tympanic membrane (TM has no effect on the magnitude of hearing loss in acute TM perforations while it is significant in chronic ones.

Ijaduola Taiwo G

2009-01-01

72

Early detection of hearing loss  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The universal newborn hearing screening (UNHS) is currently spreading in Germany, as well, even though there can be no talk of a comprehensive establishment. The introduction of UNHS in several federal states such as Hamburg, Hessen, and Schleswig-Holstein can be ascribed to the personal commitment of individual pediatric audiologists. Apart from the procurement of the screening equipment and the training of the staff responsible for the examination of the newborns, the tracking, i.e. the fol...

2010-01-01

73

Classification and hearing evolution of patients with sudden sensorineural hearing loss  

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Full Text Available The aim of this study was to analyze clinical aspects, hearing evolution and efficacy of clinical treatment of patients with sudden sensorineural hearing loss (SSNHL. This was a prospective clinical study of 136 consecutive patients with SSNHL divided into three groups after diagnostic evaluation: patients with defined etiology (DE, N = 13, 10%, concurrent diseases (CD, N = 63, 46.04% and idiopathic sudden sensorineural hearing loss (ISSHL, N = 60, 43.9%. Initial treatment consisted of prednisone and pentoxifylline. Clinical aspects and hearing evolution for up to 6 months were evaluated. Group CD comprised 73% of patients with metabolic decompensation in the initial evaluation and was significantly older (53.80 years than groups DE (41.93 years and ISSHL (39.13 years. Comparison of the mean initial and final hearing loss of the three groups revealed a significant hearing improvement for group CD (P = 0.001 and group ISSHL (P = 0.001. Group DE did not present a significant difference in thresholds. The clinical classification for SSNHL allows the identification of significant differences regarding age, initial and final hearing impairment and likelihood of response to therapy. Elevated age and presence of coexisting disease were associated with a greater initial hearing impact and poorer hearing recovery after 6 months. Patients with defined etiology presented a much more limited response to therapy. The occurrence of decompensated metabolic and cardiovascular diseases and the possibility of first manifestation of auto-immune disease and cerebello-pontine angle tumors justify an adequate protocol for investigation of SSNHL.

N.O. Penido

2009-08-01

74

Sensorineural hearing loss in insulin-dependent diabetic patients  

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Full Text Available Background: Among patients who have sensorineural hearing loss of unknown etiology, diabetes is one of the diseases to be routinely investigated. The relationship between diabetes mellitus and hearing loss is still controversial. The purpose of this study was to examine the prevalence of sensorineural hearing loss in patients with insulin-dependent diabetes mellitus (IDDM compared to control group.Methods: In a cross-sectional study pure tone audiometry (PTA and speech audiometry was performed in 62 patients with insulin-dependent diabetes mellitus (IDDM, aged under 40 years, and in 62 randomly selected age-matched non-diabetic control subjects. Subjects with otological and other metabolic diseases were excluded from the study. We applied the SPSS.10 statistical analysis software Chi-square and student's test. Results: Statistical analysis showed that the hearing of the diabetic patients were significantly worsen than the control subjects. The hearing level tended to be worsen in the diabetic patients than that in control subjects, but the differences were statistically significant only at frequencies of 250,500, 4000 and 8000 Hz p>0.05(. There wasn't statistical significant difference between sex in two study groups p>0.05(. The mean duration of diabetes was no statistically significant with hearing loss p>0.05(. The frequency of complications such as retinopathy, nephropathy, and neuropathy in the diabetic groups had no correlation with speech threshold (p>0.05(.? There were no significant differences between speech reception threshold, speech discrimination score and acoustic reflex in two groups.Conclusions: We conclude that type I diabetes mellitus can cause sensorineural hearing loss.

Koosha A.

2007-11-01

75

Assesment of Hearing Loss in Patients with Psoriasis  

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Full Text Available Background and Design: Psoriasis is an autoimmune chronic inflammatory skin disease characterized by T-cell mediated hyperproliferation of keratinocytes. Sensorineural hearing loss accompanied by autoimmune diseases was first described by McCabe in 1979. Cases of hearing loss associated with various autoimmune diseases have been reported. However, the number of studies evaluating the hearing loss in patients with psoriasis is insufficient. In this study, we aimed to assess hearing loss in psoriasis patients. Material and Methods: Fifty-one psoriasis patients, who were admitted to our outpatient clinic in 2010, and 51 healthy volunteers were included in the study. All participants underwent a complete ear, nose and throat examination before audiological assessment followed by, pure-tone audiometry in a sound-isolated audiology laboratory. Statistical analysis was performed using PASW Statistics version 18.0.0. A p-value less than 0.05 was considered statistically significant. Results: The mean bone and hearing thresholds were higher for all frequencies in patients than in controls. The values reached statistical significance at all frequencies except for right ear air conduction at 1000 Hz, bone conduction at 500 and 1000 Hz, left ear air conduction at 500 Hz, and bone conduction at 500 Hz (p<0.05. We compared the Psoriasis Area and Severity Index (PASI scores adjusted for age and disease duration and thresholds matched with frequencies and found a significant correlation between PASI score and hearing loss at medium and high frequencies. Conclusion: In psoriasis, chronic inflammation is thought to be the main pathological process destroying structure and functions of skin, nails and joints. We think that the same process may affect the cochlea in a similar way. The correlation between high PASI scores and hearing loss at medium and high frequencies may be an unexpected result of increased inflammatory mediators responsible from the disease in exacerbation periods.

Serdar Cenk Güvenç

2012-03-01

76

Sensorineural Hearing Loss in Pseudoexfoliation Syndrome  

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Full Text Available

PURPOSE: To determine hearing thresholds at sound frequencies important for speech comprehension in subjects with ocular pseudoexfoliation (PXF and to compare them with that of controls without PXF. METHODS: Eighty-three subjects with ocular PXF and 83 age and sex matched controls without PXF were enrolled in this case-control study. Pure tone audiometry (bone conduction was performed at 1, 2 and 3 kilohertz (KHz in all subjects. Thresholds were compared to an age and sex stratified standard (ISO7029 and between study groups. Hearing loss was defined as sum of tested hearing thresholds (HTL-1,2,3 lower than the ISO7029 standard median. RESULTS: The study included 60 male and 23 female subjects in each group. Hearing loss was present in 147 of 166 (88.6% of examined ears in the case group vs 89 of 166 (53.6% in the control group (P < 0.001; odds ratio [OR] = 6.69; 95% confidence interval [CI], 3.49-11.79. Overall 78 subjects (94.0% in the case group vs 58 subjects (69.9% in the control group had hearing loss in one or both ears (P < 0.001; OR=6.72; 95%CI, 2.42-18.62. Hearing thresholds at each of the examined frequencies and the HTL-1,2,3 were also significantly higher in individuals with PXF. Although glaucoma was significantly more common in subjects with PXF (51.8% vs 22.9%, P < 0.001, it was not associated with hearing loss in any of the study groups. CONCLUSIONS: Hearing thresholds at frequencies which are important for speech comprehension are significantly worse in individuals with ocular PXF as compared to matched controls. This finding may support the multi-organ nature of PXF syndrome.

 
 
81

The comparative study of reading comprehension in normal-hearing and hearing-loss student  

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Full Text Available Background and Aim: In different language approaches, reading is considered as a major skill. Language skills comprising listening, speaking, reading and writing are completely interlinked with each other. Thus, providing active application of listening and speaking skills, children will learn reading and writing skills easily. The aim of this research was to compare reading skills of hearing-loss students studying at exceptional schools with normal students of different degrees.Methods: The research was conducted post-traumatically using standardized 2006 PIRLS test. 80 students in fifth grade of exceptional primary schools, and first and fourth grade of exceptional high schools in Tehran City who had severe and or profound hearing loss were randomly selected along with 80 normal students in ordinary schools who were selected using available sampling method.Results: There were significant differences between reading comprehension of hearing-loss and normal students of all three grades (p<0.001. Reading comprehension in female students was significantly higher than the male ones (p<0.001. There were not any significant differences in mean reading comprehension scores of hearing-loss students in different grades which demonstrate that their reading skills had not developed in tandem with their age and school educations.Conclusion: This study shows that one of the significant concerns regarding hearing-loss students is their reading comprehension ability. Considering reading ability as one of the most important acquisitive abilities which students learn at school, evaluation of reading skills of hearing loss students as well as recognition of their strengths and weaknesses in this field is indispensable.

Gholamali Afrooz

2012-06-01

82

[Effect of noise and other factors damaging to hearing on hearing loss].  

Science.gov (United States)

The goal of the present paper was to investigate the relationship between hearing loss and noise exposure. Moreover, the author also examined the question whether damaging factors detected in the case history (hereditary susceptibility, toxic and infectious-toxic factors, cerebral and acoustic trauma, war, tinnitus) and working conditions (ototoxic industrial substances, shift work, hearing protection) affect hearing loss in any way. A tone and speech audiogram of 1020 persons exposed to industrial noise in a power station and non-exposed persons was evaluated for this purpose. In addition to exposure at the respective place of work, the sound intensity and total period of employment were also taken into consideration. The noise exposure of the persons working in industrial noise exceeded the limits of hearing damage, although it generally amounted to levels of less than 95 dB (A). Hearing loss in persons exposed to industrial noise increases as the noise level increases. In the intensities we examined, however, the level of sound appears to be less decisive in its effect than generally assumed. The effect of time on the threshold of hearing, on the other hand, is of importance at evaluation levels of less than 90 dB (A). In addition to age and occupational noise exposure, the following factors are significantly correlated to the threshold of hearing: hereditary susceptibility, traumata, war, tinnitus and shift work. On the whole, the factors and working conditions recorded in the case history have a considerable effect on hearing loss and are approximately equivalent to the noise at sound levels up to about 90 dB (A). PMID:6700339

Irion, H

1984-02-01

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The Relationship between Nonverbal Cognitive Functions and Hearing Loss  

Science.gov (United States)

Purpose: This study investigated the relationship between hearing loss and memory and attention when nonverbal, visually presented cognitive tests are used. Method: Hearing loss (pure-tone audiometry) and IQ were measured in 30 participants with mild to severe hearing loss. Participants performed cognitive tests of pattern recognition memory,…

Zekveld, Adriana A.; Deijen, Jan Berend; Goverts, S. Theo; Kramer, Sophia E.

2007-01-01

84

Syndromes of hearing loss associated with visual loss.  

Science.gov (United States)

Patients with hearing loss depend more on their vision on their communication and vice versa. ENT physician faces difficult situation when he or she consults a patient complaining of hearing loss with a problem of vision. The prevalence of ophthalmic abnormalities in deaf population is also higher compared to their hearing peers. This paper is to summarize the common syndromes associated with visual defect according to the site of affection in the eye. Study design: Review article. Syndromes which result in deaf blind person are different among adults compared to among children. Rubella syndrome and Down syndrome are the main causes of deaf blind people above 18 years of age. While in children, CHARGE syndrome is the main cause of deaf blind children. ENT physician should be aware of these syndromes for earlier detection of deaf blind persons. Deaf blind people need a great deal of help. Communication and education are crucial for them and need to be properly supported. PMID:23632871

Abou-Elhamd, Kamal Ahmed; ElToukhy, Hesham Mohamed; Al-Wadaani, Fahad Abdullah

2014-04-01

85

Perda auditiva genética / Genetic hearing loss  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese O progresso das pesquisas relacionadas à perda auditiva genética tem provocado um importante avanço do entendimento dos mecanismos moleculares que governam o desenvolvimento, a função, a resposta ao trauma e o envelhecimento do ouvido interno. Em países desenvolvidos, mais de 50% dos casos de surdez [...] na infância é causada por alterações genéticas e as perdas auditivas relacionadas à idade têm sido associadas com mecanismos genéticos. OBJETIVO: O objetivo desta revisão é relatar as informações mais recentes relacionadas às perdas audtivas de origem genética. FORAMA DE ESTUDO: Revisão sistemática. MATERIAL E MÉTODO: A revisão da literatura inclui artigos indexados à MEDLINE (Biblioteca Nacional de Saúde, NIH-USA) e publicados nos últimos 3 anos, além das informações disponíveis na Hereditary Hearing Loss Home Page. CONCLUSÃO: Os recentes avanços no entendimento das perdas auditivas de origem genética têm favorecido a nossa compreensão da função auditiva e tornado o diagnóstico mais apurado. Possivelmente, no futuro, este conhecimento também proporcionará o desenvolvimento de novas terapias para o tratamento das causas genéticas das perdas auditivas. Abstract in english The progress in the research of genetic hearing loss has advanced our understanding of the molecular mechanisms that govern inner ear development, function and response to injury and aging. In the developed world, over 50% of childhood deafness is attributable to genetic causes and even age-related [...] hearing loss has been associated with genetic mechanisms. AIM: The objective of this review is to summarize recent knowledge in genetic hearing loss. STUDY DESIGN: Sistematic review. MATERIAL AND METHODS: The literature review included articles indexed at MEDLINE (The National Library of Medicine, The National Institute of Health - USA) focusing on publications from the past 3 years plus the information available at the Hereditary Hearing Loss Home Page. CONCLUSION: Advances in the genetics of hearing loss have enhanced our comprehension of auditory function and have enabled more accurate diagnosis. Hopefully, as we further understand the molecular elements of the auditory system, this knowledge will help in the development of new therapies for the treatment of the underlying genetic defects.

Ricardo, Godinho; Ivan, Keogh; Roland, Eavey.

86

Perceived hearing handicap of patients with unilateral or mild hearing loss.  

Science.gov (United States)

Using the Hearing Handicap Inventory for Adults (HHIA), we assessed self-perceived hearing handicap in a sample of 63 patients having either unilaterally normal hearing or a mild hearing loss (pure tone average < or = 40 dB hearing level). Large intersubject variability in responses to the HHIA confirmed observations that reactions to minimal hearing impairment vary greatly among patients. The individual differences in responses highlight the importance of quantifying the perceived communication and psychosocial handicap, which cannot be determined from the audiogram alone. An item examination of responses to the HHIA revealed a number of emotional and social-situational problems encountered by patients with minimal hearing loss. PMID:9078932

Newman, C W; Jacobson, G P; Hug, G A; Sandridge, S A

1997-03-01

87

Weather conditions and sudden sensorineural hearing loss  

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Abstract Background Climatic or meteorological condition changes have been implicated in the pathogenesis of Idiopathic Sudden Sensorineural Hearing Loss (ISSHL). We investigated the seasonal distribution of ISSHL and evaluated the influence of meteorological parameters (such as temperature, humidity, and atmospheric pressure), their variation and covariation on the incidence of the disease. Methods A total of 82 cases of ISSHL, admitted to our department over a...

2002-01-01

88

Pseudoexfoliation Syndrome and Sensorineural Hearing Loss  

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Introduction: Pseudoexfoliation syndrome (PXS) occurs due to the deposition of extracellular fibrillar materials on the anterior chamber of the eye. This syndrome has been considered to be part of a systemic disease with the potential involvement of the inner ear called sensoroneural hearing loss (SNHL).  In this study, we aimed on evaluating SNHL within PXS patients in Iran to compare them with other international reports. Materials and Methods: In total, 33 patients with PXS and 33 age and...

Ramin Zojaji; Ali Alesheykh; Mohammad Reza Sedaghat; Kiamarz Navia; Morteza Mazloom Farsi Baf; Masoud Khaki; Aliasghar Raouf

2011-01-01

89

Studying VEMP in Sudden Sensorineural Hearing Loss  

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Introduction: Sudden sensorineural hearing loss (SSNHL) has a prevalence of 10 in 100,000. Viral infections, vascular obstruction and rupture of the intracochlear membranes are supposed to be its most common etiologies. About 40% of patients experience vertigo or imbalance. The VEMP (vestibular evoked myogenic potentials) test is a known approach for detailed study of the labyrinth. The advantage of this test in comparison to other tests is the selected study of sacculus and sacculocochlear p...

Mohsen Rajati; Mehdi Bakhshaee; Ebrahim Naghavi; Faezeh Hoseinnejad; Hamid Reza Rouhi; Rahman Movahhed

2011-01-01

90

Hearing Loss Signals Need for Diagnosis  

Science.gov (United States)

... hearing aids with the personal sound amplification products (PSAPs.) Although some PSAP technology is similar to that of a hearing ... intended to make up for impaired hearing. A PSAP, in contrast, is for people with normal hearing ...

91

Urografin in the Treatment of Sudden Sensorineural Hearing Loss  

Directory of Open Access Journals (Sweden)

Full Text Available The present study was conducted to find out whether combined treatment of intravenous urografin and corticosteroid has a therapeutic advantage over oral corticosteroid therapy in the treatment of Sudden Sensorineural Hearing Loss (SSNHL. The design of the study was an interventional and controlled clinical trial. Between 2003 and 2005, patients with SSNHL were treated in our center in Tabriz, Iran. Patients were selected if they had a hearing loss of at least 30 dB in at least 3 frequencies on audiometric testing. Audiograms were performed before admission, 1 and 2 weeks and 1 and 2 months after treatment. Patients who were put on bed rest and received intravenous urografin and hydrocortisone were compared with outpatients treated with oral steroid alone. Various descriptive analytical calculations and both Chi-square and t-test were used to analyze the data. Sixty patients were included in this study. Fifty-one patients referred to the otological clinics for the appropriate treatment within the first two weeks after the onset of hearing loss. The overall improvement of both groups was 53.3%. Seventeen (56.6% of 30 patients treated in the inpatient group who received intravenous urografin and intravenous corticosteroid had hearing improvement, while half of the outpatient group received oral corticosteroid responded positively to the treatment (p>0.05. This study revealed no significant difference in hearing improvement between the hospitalized patients who received intravenous urografin and corticosteroid and the patients who received oral corticosteroid alone.

Javad S. Totonchi

2008-01-01

92

Hereditary hearing loss with thyroid abnormalities.  

Science.gov (United States)

Mutations in SLC26A4 can cause deafness and goiter in Pendred syndrome (PDS) or isolated non-syndromic enlargement of the vestibular aqueduct (NSEVA). PDS is one of the most common hereditary causes of deafness. It is characterized by autosomal-recessive inheritance of sensorineural hearing loss, enlarged vestibular aqueducts (EVA), and an iodide organification defect with or without goiter. The diagnosis is confirmed by detection of two mutant alleles of SLC26A4 in a patient with EVA. The perchlorate discharge test can detect the underlying thyroid biochemical defect and is useful for the evaluation of goiter or for the clinical diagnosis of PDS in a patient with a non-diagnostic SLC26A4 genotype. SLC26A4 encodes the pendrin polypeptide, an anion exchanger that, in recombinant expression systems, transports chloride, bicarbonate, and iodide. Investigation of pendrin function in the inner ear has been facilitated by the Slc26a4(?) (knockout) mouse model, but the exact mechanism of its hearing loss remains unclear, as does pendrin's principal transport function in the inner ear. Treatment of PDS is focused upon rehabilitation of hearing loss, and surveillance and management of goiter and, less commonly, hypothyroidism. PMID:21358184

Choi, Byung Yoon; Muskett, Julie; King, Kelly A; Zalewski, Christopher K; Shawker, Thomas; Reynolds, James C; Butman, John A; Brewer, Carmen C; Stewart, Andrew K; Alper, Seth L; Griffith, Andrew J

2011-01-01

93

Weather conditions and sudden sensorineural hearing loss  

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Full Text Available Abstract Background Climatic or meteorological condition changes have been implicated in the pathogenesis of Idiopathic Sudden Sensorineural Hearing Loss (ISSHL. We investigated the seasonal distribution of ISSHL and evaluated the influence of meteorological parameters (such as temperature, humidity, and atmospheric pressure, their variation and covariation on the incidence of the disease. Methods A total of 82 cases of ISSHL, admitted to our department over a five-year period, were enrolled in the study. Seasonal distribution of the disease was investigated by dividing the year in four seasons. Meteorological data included daily values of 13 distinct parameters recorded at the meteorological station of the University of Ioannina during this period. A relationship between each meteorological variable and the incidence of ISSHL was investigated by applying (?2 test on data from 13 contingency tables as well as by using logistic regression and t-test approaches. In addition, the influence of different weather types on the incidence of ISSHL was investigated using Cluster Analysis in order to create eight clusters (weather types characteristic for the prefecture of Ioannina. Results The results of the study could not indicate any seasonal distribution of the disease. The incidence of ISSHL could not be significantly correlated either to any distinct meteorological parameter or to any specific weather type. Conclusions Meteorological conditions, such as those dominating in the Northwestern Greece, and/or their changes, have no proven effect on the incidence of ISSHL.

Kateri Maria

2002-07-01

94

???????????????????? Intratympanic Glucocorticoids for Sudden Sensorineural Hearing Loss: A Systematic Review  

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Full Text Available ?????????????????????????????????????????????? ????? Cochrane Library, PubMed, EMBASE, CBM, CNKI, VIP?????????????????????????(ITDvs ???????????/?????????????(RCT??? Cochrane Handbook 5.0.1 ??????????????? RevMan 5.0.2 ????Meta ????????5 ? RCTs?? 285 ????Meta ???????????????????OR(95% CI?3.94(1.03,15.12???????????(ITD?250 HZ???????????????(p < 0.05?????????????????????????(p = 0.20????????????????????????????????????????????????????????????Objective To assess the efficacy and safety of intratympanic glucocorticoids for sudden sensorineural hearing loss. Methods We searched the Cochrane Library, PubMed, EMBASE, CBM,CNKI, and VIP databases and International Clinical Trials Registry website of World Health Organization using the key words “glucocorticoids”, “hearing loss” for the literatures of English and Chinese. Randomized controlled trials (RCTs of intratympanic glucocorticoids versus placebo or intratympanic glucocorticoids versus controlled group?oral glucocorticoid/placebo?for sudden sensorineural hearing loss were included. According to the Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.1, we assessed the quality of the included RCTs. A meta-analysis was carried out with the Cochrane Collaboration’s software RevMan 5.0.2. Results Five RCTs which contained 285 patients were included. Meta-analysis illustrated that there was sta-tistically significant on hearing recovery rate between the two groups (OR:3.94, 95% CI: 1.03-15.12. Hearing of pure tone average also improved significantly with intratympanic glucocorticoids therapy at 250HZ (p < 0.05. We found no statistically significant on the speech reception threshold (p = 0.20. Conclusion Com-pared with the control group, intratympanic glucocorticoids can significantly increase the hearing recovery rate of patients. Given the limitation of sample size of included studies into consideration, the results of this systematic review are still uncertain. Multi-center, large-scale, double-blinded randomized control trials are needed to confirm the available evidence.

??

2011-05-01

95

The impact of hearing loss on the quality of life in adults  

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Full Text Available Introduction. The hearing apparatus is one of the most important factors related to the development of oral communication. Thus, hearing disorders and deafness lead to severe handicap. Hearing impairment in adults cause verbal communication disorders that influence psychical, emotional and social functioning. Nowadays, there is a noticeable world tendency towards improving hard of hearing person’s quality of life. Objective. Objective was to assess the association between hearing impairment and health-related quality of life. Methods. A hundred adults with billateral hearing impairment underwent hearing examination and answered the Hering Handicap Inventory for the Elderly-Screening (HHIE-S, Ventry and Weinstein, specific for hearing impairment. Results. Almost half of all participants (44% had a moderate hearing loss, and 36% had a mild loss. Infrequently, participants had a severe degree of hearing loss (13% and deafness (7%. Self reported hearing handicap revealed significant emotional, social and situational dysfunctions (?2=40.960; df=1; p<0.01. Severity of hearing loss was significantly correlated with hearing handicap (r=0.212; p<0.05. More often, participants revealed social and situational than emotional hearing handicap (?2=131.89; df=100; p<0.05. Only 12% of all participants habitually used hearing aids, and they observed a significantly better quality of life scores (?2=6.23; df=1; p<0.05. Conclusion. Health-related quality of life must be estimated as a factor of great importance. Investigations should involve a more extansive population with hearing loss and a national programme should be started.

Tatovi? Milica

2011-01-01

96

Role Salience and Anticipated Work–Family Relations Among Young Adults With and Without Hearing Loss  

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This study examined the effect of hearing status on role salience and anticipated work–family relations among 101 unmarried young adults aged 20–33 years: 35 with hearing loss (19 hard of hearing and 16 deaf) and 66 hearing. Participants completed the Life Role Salience scale, anticipated conflictual relations scale, anticipated facilitory relations scale, and a background questionnaire. The deaf participants demonstrated a significantly higher level of commitment to work but anticipated ...

2008-01-01

97

Reported Causes of Hearing Loss for Hearing Impaired Students; United States 1970-71.  

Science.gov (United States)

Reported are causes of hearing loss for 41,109 hearing impaired students enrolled in 555 special educational programs as part of a national annual survey during the 1970-71 school year. Data is provided on the relationship between hearing loss etiology and the following variables: age and sex of students, additional handicapping conditions, family…

Gentile, Augustine; Rambin, J. Bentley

98

Vision loss and hearing loss in painting and musical composition.  

Science.gov (United States)

This article considers the impact of vision and hearing loss on great painters and musical composers. The visual work of Mary Cassatt, Georgia O'Keeffe, Edgar Degas, and Claude Monet all showed alterations as their vision failed. In contrast, Gabriel Fauré, Bed?ich Smetana, and Ludwig von Beethoven wrote many of their best compositions while totally deaf, and Georg Friedrich Handel and Frederick Delius struggled to compose late in life when they lost their vision (although their hearing remained excellent). There are 2 major distinctions between the role of vision and hearing for these artistic disciplines. First, there is a surrogate means of "hearing" music, through the musical score, which allows composers to write and edit music while totally deaf. The greatest problem with deafness for a skilled composer is interference from internal noise (tinnitus). There is no surrogate for vision to allow a painter to work when the subject is a blur or the colors on the canvas cannot be distinguished. Second, although the appreciation of art is visual and that of music is auditory, the transcription of both art and musical composition is visual. Thus, visual loss does pose a problem for a composer accustomed to working with good sight, because it disrupts habitual methods of writing and editing music. PMID:24565744

Marmor, Michael F

2014-07-01

99

The pathogenesis of Noise Induced Hearing Loss  

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Full Text Available NIHL occurs when too much sound intensity is transmitted into and through the auditory system and can be occur following a shot gun or the exposure to a moderately intense sound for a long period of time. NIHL caused by acoustic trauma refers to permanent cochlear damage from a one-time exposure to excessive sound pressure. This form of NIHL commonly results from exposure to high-intensity sounds such as explosions, gunfire, a large drum hit loudly and firecrackers. Meanwhile the sound intensity, duration of exposure and personal hearing thresholds as the effective factors in the amount of noise induced hearing loss should not be overlooked.  Since numerous investigations have been performed about intense sudden sound we will discuss it in detail in the current article.

Seyyed Abbas Mir Vakili

1999-03-01

100

Noise-induced hearing loss milestones: past and future  

Scientific Electronic Library Online (English)

Full Text Available SciELO South Africa | Language: English Abstract in english A retrospective study was conducted on the Rand Mutual Assurance (RMA) noise-induced hearing loss (NIHL) compensation claims from 1998 to 2008 to determine if the 2008 milestone agreed at the 2003 Mine Health and Safety Summit was achieved. The number and costs of NIHL compensation claims in differe [...] nt commodity sectors and workplaces were collated. A secondary analysis of the ages of employees compensated after 2008 was conducted. A complementary retrospective analysis of audiogram data investigated the percentage loss of hearing (PLH) shift in different homogeneously exposed groups and occupations at two gold mines. The compensation claims analysis indicated a significant decrease in NIHL claims from 1998 to 2008, but the milestone was not achieved. The reason may be either that claims have not been submitted timeously as required by Instruction 171 and that the current submissions are a result of pre-2003 noise exposure, or that employees who were baselined are still developing NIHL owing to ineffective hearing conservation programmes in place in the mining industry. On the basis of best practice for hearing conservation, recommendations are made for leading indicators in hearing conservation programmes and for reducing the risks of NIHL in order to achieve the 2013 milestone.

A.L., Edwards; D., Kritzingert.

 
 
 
 
101

MR imaging of sensory neural hearing loss  

International Nuclear Information System (INIS)

This paper describes MR findings in patients with sensorineural hearing loss (SNHL) who do not have acoustic neuromas. Twenty-eight patients with SNHL were evaluated with pre- and postgadolinium thin-section axial T1-weighted imaging and axial T2- weighted imaging through the whole brain. Eleven patients had lesions in the labyrinth. Ten of the 11 lesions enhanced after gadolinium administration. The diagnoses included viral labyrinthitis (three patients), syphilitic labyrinthitis (two patients), bacterial labyrinthitis (one patient), vestibular neuromas (three patients), ostosclerosis (one patient), and intravestibular hemorrhage (one patient)

1990-11-25

102

Preliminary comparison of infants speech with and without hearing loss  

Science.gov (United States)

The speech of ten children with hearing loss and ten children without hearing loss aged 12 months is examined. All the children with hearing loss were identified before six months of age, and all have parents who wish them to become oral communicators. The data are from twenty minute sessions with the caregiver and child, with their normal prostheses in place, in semi-structured settings. These data are part of a larger test battery applied to both caregiver and child that is part of a project comparing the development of children with hearing loss to those without hearing loss, known as the Early Development of Children with Hearing Loss. The speech comparisons are in terms of number of utterances, syllable shapes, and segment type. A subset of the data was given a detailed acoustic analysis, including formant frequencies and voice quality measures. [Work supported by NIDCD R01 006237 to Susan Nittrouer.

McGowan, Richard S.; Nittrouer, Susan; Chenausky, Karen

2005-04-01

103

Age-related changes in auditory and cognitive abilities in elderly persons with hearing aids fitted at the initial stages of hearing loss  

Directory of Open Access Journals (Sweden)

Full Text Available In this study, we investigated the relation between the use of hearing aids at the initial stages of hearing loss and age-related changes in the auditory and cognitive abilities of elderly persons. 12 healthy elderly persons participated in an annual auditory and cognitive longitudinal examination for three years. According to their hearing level, they were divided into 3 subgroups - the normal hearing group, the hearing loss without hearing aids group, and the hearing loss with hearing aids group. All the subjects underwent 4 tests: pure-tone audiometry, syllable intelligibility test, dichotic listening test (DLT, and Wechsler Adult Intelligence Scale-Revised (WAIS-R Short Forms. Comparison between the 3 groups revealed that the hearing loss without hearing aids group showed the lowest scores for the performance tasks, in contrast to the hearing level and intelligibility results. The other groups showed no significant difference in the WAIS-R subtests. This result indicates that prescription of a hearing aid during the early stages of hearing loss is related to the retention of cognitive abilities in such elderly people. However, there were no statistical significant correlations between the auditory and cognitive tasks.

M. Shiroma

2011-05-01

104

Acute unilateral hearing loss as an unusual presentation of cholesteatoma  

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Abstract Background Cholesteatomas are epithelial cysts that contain desquamated keratin. Patients commonly present with progressive hearing loss and a chronically discharging ear. We report an unusual presentation of the disease with an acute hearing loss suffered immediately after prolonged use of a pneumatic drill. Case presentation A 41 year old man with no previous history of ear problems presented with a sudden loss of hearing in his right ear immediately ...

Thio Daniel; Ahmed Shahzada K; Bickerton Richard C

2005-01-01

105

Sensorineural hearing loss in insulin-dependent diabetic patients  

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Background: Among patients who have sensorineural hearing loss of unknown etiology, diabetes is one of the diseases to be routinely investigated. The relationship between diabetes mellitus and hearing loss is still controversial. The purpose of this study was to examine the prevalence of sensorineural hearing loss in patients with insulin-dependent diabetes mellitus (IDDM) compared to control group.Methods: In a cross-sectional study pure tone audiometry (PTA) and speech audiometry was perfor...

2007-01-01

106

Association between Ocular Pseudoexfoliation and Sensorineural Hearing Loss.  

Science.gov (United States)

Background. Our study aimed to investigate an association between ocular pseudoexfoliation (PXF) and sensorineural hearing loss (SNHL) and to compare them with age and sex matched controls without pseudoexfoliation. Method. This was a case-control study of 123 patients which included 68 cases with PXF (at least one eye) and 55 controls without pseudoexfoliation. Pure-tone audiometry (PTA) was done for these patients at sound frequencies taken as important for speech comprehension, that is, 250 Hertz (Hz), 500?Hz, 1000?Hz, and 2000?Hz. Results. There were 41 patients with pseudoexfoliation syndrome (PXE) and 27 with pseudoexfoliative glaucoma (PXEG). The majority of patients with hearing loss (60%; n = 51) were PXF patients and the remaining 40% (n = 34) were controls. Below average hearing thresholds were significantly higher in the pseudoexfoliation group compared to the control group (P = 0.01; odds ratio (OR), 3.00; 95% confidence interval (CI), 1.25-7.19). However, there was no significant difference in the mean hearing threshold levels between the three groups (PXE, PXEG, and controls) in either ear (ANOVA, right ear: P = 0.46 and left ear P = 0.36). Conclusion. Our study found an association between PXF and SNHL, confirming that PXF can involve organs in the body other than the eye. PMID:24864196

Singham, Nandini Vijaya; Zahari, Mimiwati; Peyman, Mohammadreza; Prepageran, Narayanan; Subrayan, Visvaraja

2014-01-01

107

Sudden Sensorineural Hearing Loss: MR Imaging.  

Science.gov (United States)

Hearing loss greater than 30 dB over three contiguous pure-tone frequencies occurring within a three day period is defined as sudden hearing loss. It is usually sensorineural (SSNHL), unilateral and appears as an otologic emergency. SSNHL has many possibile etiologies such as: labyrinthine viral infection, ischemic or hemorrhagic illness, trauma, immuno-mediated inner ear disease, tumor, inner ear malformation, and an imbalance between perilymphatic and endolymphatic fluid pressure. Nevertheless in almost 80% of cases SSNHL belongs to the idiopathic category because the etiology is unknown. The aim of this study was to test the diagnostic impact of two MR devices. Fifteen cases of SSNHL studied with a 1.5 T unit in our hospital between January 2006 and December 2008 within two weeks of the onset were retrospectively evaluated. Since January 2009 three more patients affected by SSNHL have been scanned with a 3T MR unit. We discuss the diagnostic sensitivity, clinical usefulness and the cost-benefit ratio of the MR systems. PMID:24148533

Canapicchi, R; De Marchi, D; Lombardo, F; Fortunato, S; De Cori, S; Montanaro, D; Berrettini, S

2010-04-01

108

Studying VEMP in Sudden Sensorineural Hearing Loss  

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Full Text Available Introduction: Sudden sensorineural hearing loss (SSNHL has a prevalence of 10 in 100,000. Viral infections, vascular obstruction and rupture of the intracochlear membranes are supposed to be its most common etiologies. About 40% of patients experience vertigo or imbalance. The VEMP (vestibular evoked myogenic potentials test is a known approach for detailed study of the labyrinth. The advantage of this test in comparison to other tests is the selected study of sacculus and sacculocochlear pathways. Materials and Methods:  In this cross sectional study all patients with SSNHL diagnosis were admitted and underwent routine standard treatments and diagnostic tests. Clinical symptoms and paraclinic findings were recorded in especially designed forms and VEMP test was performed on admission. Results: Among the 43 cases with sudden sensorineural hearing loss, 14 (32.6% had vertigo. Thirteen patients (39.2% out of 43 had a negative (abnormal VEMP, 6 of which (42.9% had vertigo, while in the 30 VEMP positive (normal cases, vertigo was detected in 8 (26.6%. Discussion: Saccular dysfunction seems to be an important finding in SSNHL. Although it is more prevalent in the patients with vertigo, it can be found in the non-dizzy cases. VEMP disturbance in SSNHL shows more extensive pathological involvement. Conclusion: In SSNHL the pathology isn’t limited to the cochlea and even in patients with no vestibular symptoms sacculus might be involved.

Mohsen Rajati

2011-03-01

109

Hearing Loss Due to Familial Hypercholesterolemia and Statin Treatment  

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Full Text Available It has been suggested that high cholesterol levels might have adverse effects on hearing and interest- ingly statins may have beneficial effects on hearing loss. Herein, we share a dramatic improvement in acute hearing loss by statin administration in a young patient with familial hypercholesterolemia. To our knowledge this is the first report indicating the possible role of statins in patients suffering from sudden hearing loss in the context of familial hypercholesterolemia. Although the statin administra- tion as a therapeutic option for sudden hearing loss needs to be clarified in prospective studies, this case report might shed more light for possible association of dyslipidemia and hearing loss and role of statins in such cases.

Muhammed Oylumlu

2013-01-01

110

Hearing loss and disability exit: measurement issues and coping strategies  

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Using unique representative data containing self-reported functional and clinically measured hearing ability for the Danish population aged 50-64, we estimate the effect of hearing loss on receipt of disability benefits accounting for potential endogeneity of functional hearing. Our identification strategy involves simultaneous estimation of labor supply, functional hearing and coping strategies i.e. using assistive devices at work or informing one's employer about the problem. We find that f...

Christensen, Vibeke T.; Gupta, Nabanita Datta; Rasmussen, Martin V.

2007-01-01

111

Hearing Aids Communication : Integrating Social Interaction, Audiology and User Centered Design to Improve Communication with Hearing Loss and Hearing Technologies  

DEFF Research Database (Denmark)

Globally, hearing loss is the second most frequent disability. About 80% of the persons affected by hearing loss do not use hearing aids. The goal of this edited volume is to present a theoretically founded, interdisciplinary approach geared at understanding and improving social interaction impacted by hearing loss and (non-) use of hearing technologies. The researchers report on pilot studies from Australia, Denmark, Finland, Germany, Switzerland and the USA. Using Conversation Analysis, the studies identify problems and serve as points of departure for possible solutions. Researchers and practitioners from the different disciplines (medicine, audiology, hearing rehabilitation, User Centered Design, Conversation Analysis, change business) as well as users of hearing technologies comment on this approach.

2012-01-01

112

Connexin 26 and autosomal recessive non-syndromic hearing loss  

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Full Text Available Prelingual deafness occurs with a frequency of 1 in 1000 live births and is divided into syndromic and non-syndromic forms contributing 40 and 60% respectively. Autosomal recessive non-syndromic hearing loss (ARNSHL is responsible for 80% cases of childhood deafness. Nearly all genes localized for ARNSHL cause prelingual, severe to profound, sensorineural hearing impairment. ARNSHL is genetically heterogeneous and at least 39 loci have been identified. The most significant finding to date has been the discovery of mutations in GJB2 gene at the DFNB1 locus on chromosome 13q12 as the major cause of profound prelingual deafness. This was first reported in a Tunisian family in 1994 and thereafter in many different countries. GJB2 gene encodes the gap-junction protein, connexin 26 (Cx26, mutations in which have become the first genetic marker of inherited hearing loss. Allele-specific polymerase chain reaction (AS-PCR, single stranded conformation polymorphism (SSCP and sequencing methods have been developed for the detection of mutations in Cx26 gene. In India as well, the Cx26 mutations are being screened in families with hearing impaired children using these molecular methods. Therefore, in order to create awareness among the clinicians and the affected families; we have attempted to review the Cx26 gene mutations responsible for autosomal recessive type of non-syndromic hearing loss. The efficacy and utility of Cx26 gene analysis might open the path to proper counseling of families for carrier detection and prenatal diagnosis. It may even facilitate the development of strategies in future for the treatment of this common genetic disorder.

Mukherjee Monisha

2003-01-01

113

Temporal intra-speech masking of plosive bursts: Effects of hearing loss and frequency shaping  

Science.gov (United States)

PURPOSE The purposes were 1) to compare masking of consonant bursts by adjacent vowels for listeners with and without hearing loss and 2) to determine the extent to which the “temporal intra-speech masking” can be reduced by a simulated hearing aid frequency-response shaping. METHOD Fourteen adults with sensorineural hearing loss and six with normal hearing served as participants. Seven of the participants with hearing loss had flat/gradually sloping audiograms and seven had steeply sloping losses. Stimuli consisted of three consonant bursts (/t/, /p/, /k/) presented in isolation and in vowel-consonant-vowel combinations using the vowel /a/ with formant transition information removed. Normal-hearing listeners were tested using unfiltered stimuli. Listeners with hearing loss were tested using unfiltered stimuli and stimuli filtered to approximate a hearing aid frequency response prescribed by NAL-R. All listeners were tested under earphones at the most comfortable level for the vowel stimulus. Temporal intra-speech masking was quantified as the threshold shift produced by the adjacent vowels. RESULTS Average intra-speech masking for listeners with steeply sloping hearing loss was significantly higher than that of normal-hearing listeners and those with flat/gradually sloping losses. Greater intra-speech masking was observed for /t/ and /p/ than for /k/. On average, frequency shaping significantly reduced the amount of intra-speech masking for listeners with steeply sloping hearing losses. Even with appropriate amplification/spectral shaping, however, temporal intra-speech masking remained greater than normal for several individuals. CONCLUSIONS Finding suggest that some individuals with steeply sloping losses may need additional signal processing to supplement frequency-shaping in order to overcome the effect of temporal intra-speech masking.

Mackersie, Carol L.

2010-01-01

114

Association between Hearing Loss and Saccular Dysfunction in Older Individuals  

Science.gov (United States)

Objective (1) Describe the association between hearing loss and dysfunction of each of the five vestibular end-organs – the horizontal, superior and posterior semicircular canals, saccule and utricle – in older individuals. (2) Evaluate whether hearing loss and vestibular end-organ deficits share any risk factors. Study design Cross-sectional study. Setting Academic medical center. Patients Fifty-one individuals age ?70. Interventions Audiometry, head-thrust dynamic visual acuity (htDVA), sound-evoked cervical vestibular-evoked myogenic potential (cVEMP) and tap-evoked ocular VEMP (oVEMP). Main Outcome Measures Audiometric pure-tone averages (PTA), htDVA LogMAR scores as a measure of semicircular canal function in each canal plane, and cVEMP and oVEMP amplitudes as a measure of saccular and utricular function, respectively. Results We observed a significant correlation between hearing loss at high frequencies and reduced cVEMP amplitudes (or reduced saccular function; r = ?0.37, p potential benefit of screening individuals with presbycusis – particularly those with significant noise exposure history – for saccular dysfunction, which may contribute to fall risk in the elderly.

Zuniga, M. Geraldine; Dinkes, Roni E.; Davalos-Bichara, Marcela; Carey, John P.; Schubert, Michael C.; King, W. Michael; Walston, Jeremy; Agrawal, Yuri

2012-01-01

115

Medication for hearing loss after fractionated stereotactic radiotherapy (SRT) for vestibular schwannoma  

International Nuclear Information System (INIS)

Purpose: To investigate the effectiveness of corticosteroid treatments for patients showing decreases in hearing levels after stereotactic radiotherapy for vestibular schwannoma. Methods and Materials: Twenty-one patients experienced a hearing loss in pure-tone average at greater than 20 dB or less than 10 dB within 1 year after irradiation administration of 44 Gy/22 fractions followed by a 4 Gy boost. Eight received oral prednisone at a daily dose of 30 mg, which was gradually decreased (medicated group), and 13 received none (nonmedicated group). The average observation period was 26.7±16.6 (range: 6-69) months. Results: Hearing recovery was seen after initial onset of the hearing loss in all 8 patients in the medicated group and in 2 of 13 patients in the nonmedicated group (p=0.001). The hearing recovery, that is, the change in pure-tone average (dB) at the last follow-up from the onset of hearing loss, was 9.8±6.9 dB (recovery) in the medicated group and -9.4±12.8 dB (further loss) in the nonmedicated group (p=0.0013). The hearing recovery rate, normalizing to the degree of the hearing loss before medication, was also significantly higher in the medicated group than in the nonmedicated group (p=0.0014). Conclusions: Corticosteroidal intake is suggested to be effective in improving hearing loss after stereotactic radiotherapy, at least in young patients having a useful pretreatment hearing level, if the treatment for hearing loss is administered immediately after the hearing loss is first detected

2001-08-01

116

Disacusia neurossensorial imunomediada Immunomediated sensorineural hearing loss  

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Full Text Available A disacusia neurossensorial imunomediada (DNSI é caracterizada geralmente por uma disacusia neurossensorial bilateral, progressiva e assimétrica, acompanhada ou não por outros sintomas da orelha interna. Três pacientes com DNSI cujo quadro clínico e audiométrico eram sugestivos de doença auto-imune, e apresentaram resposta positiva à terapia imunossupressora ou pesquisa positiva de anticorpo anti hsp-70 68kD, foram estudados com relação às características clínicas, testes diagnósticos, alternativas terapêuticas e evolução da doença. Dois pacientes apresentaram quadro de disacusia neurossensorial rapidamente progressiva, associado a quadro vestibular, e outro, quadro de surdez súbita unilateral. Nenhum paciente apresentou positividade às provas reumatológicas, e apenas um paciente apresentou aumento na velocidade de hemossedimentação. Nenhum paciente obteve resposta adequada sustentada à corticoterapia, mas dois deles melhoraram com outras terapias imunossupressoras. O diagnóstico da DNSI é clínico e baseado na resposta positiva ao teste terapêutico com imunossupressores. A pesquisa de anticorpo anti-hsp70 de 68 kD pelo Western Blot é o único exame laboratorial específico para seu diagnóstico, possuindo sensibilidade de 42% e especificidade de 90%. Apenas 1 paciente apresentou positividade para este teste e não respondeu à terapia imunossupressora. Os dois pacientes com teste negativo responderam satisfatoriamente ao tratamento. A baixa sensibilidade do Western Blot e seu alto custo dificultam sua difusa utilização em nosso meio. A introdução precoce do tratamento é de suma importância por auxiliar no diagnóstico e por proporcionar um melhor prognóstico auditivo.The immunomediated sensorineural hearing loss (ISHL is characterized as an asymmetric and progressive sensorineural hearing loss. Tree patients with ISHL were studied, regarding clinical aspects, diagnostic tests, treatment options and disease evolution. They presented whether positive response to immunosuppressive therapy or positiviness to Western Blot test for hsp 70-68kD. Two patients presented rapidly progressive sensorineural hearing loss, associated to vestibular symptoms and the other presented unilateral sudden deafness. No patient reacted to rheumatological testes, and one presented increased erythrocyte sedimentation rate. None satisfactorily responded to corticotherapy, but two presented clinical improvement with other immunosuppressive therapies. The ISHL diagnosis is based on clinical aspects and on the positive response to therapeutic testes with immunosupressor drugs. The Western Blot test for hsp 70-68 kD, with 42% sensitivity and 90% specificity, is the only specific laboratorial exam for ISHL. One patient presented positiviness to this exam and did not responded to immunosuppressive therapy. Two patients with negative tests satisfactorily responded to immunosuppressive therapy. The low sensitivity and high costs of Western Blot test represent difficulties to the spread use of it. The early introduction of treatment has a major importance in the diagnosis of ISHL and to increase the auditory prognosis.

Norma de Oliveira Penido

2002-10-01

117

Prognostic factors of profound idiopathic sudden sensorineural hearing loss.  

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Profound idiopathic sudden sensorineural hearing loss is thought to have a poor prognosis, but few studies have focused on this condition. We aimed to assess the impact of patient factors, audiologic parameters, and salvage intratympanic steroid injection therapy on the prognosis of profound idiopathic sudden sensorineural hearing loss. The demographic, clinical, and audiologic data, degree of hearing recovery, and efficacy of intratympanic steroid injection therapy in 576 patients with profound idiopathic sudden sensorineural hearing loss (mean age 56.2 ± 14.9 years) who had been admitted at four tertiary referral centers between 2000 and 2011 were retrospectively reviewed. The mean hearing level at the initial presentation was 108.1 ± 9.5 dB. Many patients experienced vertigo (52.1%) and tinnitus (77.4%). At the 2-month follow-up, 172 (29.8%) patients showed some degree of hearing recovery, but only 21 (3.6%) patients recovered normal hearing. Further, the 116 patients who had received salvage intratympanic steroid injections showed a better audiologic outcome (improvement, 26.1 ± 24.3 vs. 15.7 ± 22.1 dB; P = 0.000) than those who had not (n = 429). In conclusion, a higher degree of hearing loss at the initial presentation indicates a poorer prognosis. Salvage intratympanic steroid injection therapy may improve the hearing of patients with profound idiopathic sudden sensorineural hearing loss after the failure of systemic steroid therapy. PMID:23771280

Wen, Yu-Hsuan; Chen, Peir-Rong; Wu, Hung-Pin

2014-06-01

118

Contributing Factors in Inducing Noise Induced Hearing Loss  

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Full Text Available The most common contributing factors in inducing hearing loss in adults are aging, exposure to noise and the interaction among these factors with other parameters. Individual parameters are also effective in the extent of hearing loss which is produced. Being aware of Vulnerability factors such as physical parameters, Auditory and non-auditory factors can be useful in considering a good hearing conservation program for noise induced hearing losses.In the current article we are aimed at introducing three important parameters and their sub-divisions pertaining to this issue.

Saeid Farahani

1999-03-01

119

Methadone-induced bilateral severe sensorineural hearing loss.  

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Methadone, a long-acting opiate agonist, and naltrexone, an opiate receptor antagonist, are both commonly used to treat patients with morphine and heroin addiction. We present a rare case of methadone-induced persistent bilateral sensorineural hearing loss (SNHL) after chronic naltrexone use and review opioid-induced hearing loss in the literature. Methadone-induced hearing loss has been described previously described in the literature with all reported cases recovering functional hearing. This is the first description of persistent bilateral severe SNHL following methadone ingestion. We propose opiate receptor sensitization from prolonged naltrexone use as a predisposing factor for methadone-induced irreversible cochlear injury. PMID:24051235

Vorasubin, Nopawan; Calzada, Audrey P; Ishiyama, Akira

2013-01-01

120

Cognitive workload and driving behavior in persons with hearing loss  

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Purpose To compare the effect of cognitive workload in individuals with and without hearing loss, respectively, in driving situations with varying degree of complexity. Methods 24 participants with moderate hearing loss (HL) and 24 with normal hearing (NH) experienced three different driving conditions: Baseline driving; Critical events with a need to act fast; and a Parked car event with the possibility to adapt the workload to the situation. Additionally, a Secondary task (observation and r...

Thorslund, Birgitta; Peters, Bjo?rn; Lidestam, Bjo?rn; Lyxell, Bjo?rn

2013-01-01

 
 
 
 
121

Coping with emergent hearing loss : expectations and experiences of adult, new hearing aid users ; an anthropological study in Denmark  

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The dissertation, ”Coping with emergent hearing loss”, is written in English and is based on the diversity of problems connected to hearing loss and the adaptation of hearing aids. The research was carried out in Denmark and involves adults with an emergent hearing loss, who have decided to become hearing aid users. The data is analyzed through methods of cultural anthropology with focus on the following topics: How do the new users cope with the status passage towards being hearing aid u...

Bisgaard, Susanne

2009-01-01

122

What are the audiometric frequencies affected are the responsible for the hearing complaint in the hearing loss for ototoxicity after the oncological treatment?  

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Full Text Available Introduction: The neurosensory bilateral simetric hearing loss resulting of the oncological treatment is underestimated, because the patients has the hearing detection preserved, reporting complaints in determined situation, or the not comprehension of part of the message. Objective: Investigate which are the audiometric frequencies affected are the responsible by the presence of hearing complaints. Method: Prospective study evaluating 200 patients with cancer in the childhood out of the oncological treatment in at least 8 years, with average age to the diagnosis of 6,21 years (4,71. Was applied anamnesis to investigate the presence of hearing complaints and performed a tonal threshold audiometry. To check the association between the complaint and the hearing loss, was applied the Exact test of Fisher, with one error a=5%, the patients were split into: normal hearing, hearing loss in 8kHz, loss in 6-8 kHz, loss in 4-8 kHz, loss in 2-8 kHz and loss in < 1-8 kHz. Results: We found 125 patients with hearing loss, 10 presented hearing complaints. Between the patients with hearing loss, 16 presented loss only at 8kHz, and 1 with complaint; 22 with loss in 6-8 kHz, being 3 with complaint; 16 with loss in 4-8 kHz, from them 10 with complaint; 15 with loss 2-8 kHz, being 14 with complaint and 6 with loss in < 1-8 kHz all with complaints. There were a significant relationship between the loss and hearing complaint (p<0,001, when the frequency of 4 kHz was involved. Conclusion: The bigger the number of affected frequencies the bigger the occurrence of hearing complaint, most of all when the speech frequencies are involved, and the involvement of 4 kHz already determines the appearing of the complaints.

Liberman, Patricia Helena Pecora

2012-01-01

123

Sensorineural Hearing Loss Associated with Kawasaki Disease  

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Full Text Available Kawasaki disease (KD is an acute systemic vasculitis of children characterized by fever, rash, conjunctival hyperemia, oropharyngeal erythema, edema and erythema of the hands and feet, and cervical adenopathy [1]. A variety of other features are also characteristics of this syndrome, including coronary artery aneurysms, urethritis, anterior uveitis, mild hepatobiliary dysfunction, and gallbladder hydrops. Coronary artery abnormalities, including aneurysms and ectasia, occur in approximately 20% of untreated patients [2]. Neurologic involvement is rare. Cranial nerve palsy, especially involving the seventh nerve, has been reported [3], as well as hemiparesis caused by cerebral thrombosis and infarction, and convulsions. Although about 30% of patients with acute KD in the United States have been reported to suffer mild sensorineural hearing loss (SNHL [4], only a few such cases have been reported in Japan. On the other hand, in both countries, a few cases of severe or profound SNHL in children who were in the acute phase of KD have been documented [5].

Hitoshi Tanimoto

2014-04-01

124

Hearing loss is often undiscovered, but screening is easy.  

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Screening for hearing loss should be part of the routine physical examination, but it is often not done because of time constraints. We present a quick and easy office screening test that measures the functional impact of hearing loss. We also review the steps of audiologic management that follow referral by the primary care physician. PMID:15055245

Newman, Craig W; Sandridge, Sharon A

2004-03-01

125

[Two cases of rare unilateral sensorineural hearing loss].  

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We report a case of unilateral sensorineural hearing loss due to Borrelia burgdorferi infection and in a patient with haemophilia B and hepatitis C treated with alpha-interferon. An audiological check-up of that kind of patients is indicated in order to exclude hearing loss. PMID:12741155

Obrebowski, Andrzej; Walczak, Marta; Karlik, Micha?; Wojnowski, Waldemar

2003-01-01

126

Living with Hearing and Vision Loss Due to Usher Syndrome  

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Full Text Available ... these: Living with Hearing and Vision Loss Video (Windows Media) Living with Hearing and Vision Loss Video ( ... Family of Sites AFB.org FamilyConnect ® CareerConnect ® Braille Bug ® Directory Center AccessWorld ® Journal of Visual Impairment & Blindness ...

127

Living with Hearing and Vision Loss Due to Usher Syndrome  

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Full Text Available ... Usher Syndrome Having trouble with this video? Try one of these: Living with Hearing and Vision Loss ... Vision Loss Due to Usher Syndrome Video NARRATOR 1: A woman with short gray hair. NARRATOR 2: ...

128

Effectiveness of intratympanic dexamethasone for refractory sudden sensorineural hearing loss.  

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The purpose of this study was to investigate the effectiveness of intratympanic steroids in patients with idiopathic sudden sensorineural hearing loss who did not respond to initial systemic steroid therapy. This retrospective study involved 51 patients, who did not respond to systemic steroids as a first-line treatment. Initial systemic steroid therapy consisted of administration of methylprednisolon intravenously (250 mg) at the first day and followed by orally (1 mg/kg) tapering for 14 days. Twenty-one patients accepted intratympanic treatment, and the remaining 30 patients who refused intratympanic treatment were evaluated as the control group. Steroids (dexamethasone drops, 1 mg/mL) were administered through a ventilation tube. Hearing was assessed immediately before treatment and 2 months after treatment. Recovery of hearing was defined as an improvement of >20 dB in the pure tone average. We tested 250, 500, 1,000, 2,000, 4,000, and 8,000 Hz frequencies for the pure tone audiometric evaluation. Statistically Student's t test, Mann-Whitney U test, Chi-squared and Fisher's exact tests were used. The pure tone average improved in 47.6% of the intratympanic group and in 10% of the control group (p = 0.002), with pure tone average improvements of 19.9 ± 16.5 and 4.76 ± 9.6 dB in the intratympanic and control groups, respectively. When the hearing threshold at each frequency was analyzed, improvements at all frequencies were significantly greater in the intratympanic steroid group when compared with the control group (p sensorineural hearing loss in patients, who are refractory to primary systemic steroid therapy. PMID:23771321

Erdur, Omer; Kayhan, Fatma Tulin; Cirik, Ahmet Adnan

2014-06-01

129

Comparison of Different Levels of Reading Comprehension between Hearing-Impaired Loss and Normal-Hearing Students  

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Full Text Available Background and Aim: Reading skill is one of the most important necessities of students' learning in everyday life. This skill is referred to the ability of comprehension, comment and conclusion from texts and receiving the meaning of the massage which is composed. Educational development in any student has a direct relation with the ability of the comprehension. This study is designed to investigate the effects of hearing loss on reading comprehension in hearing-impaired students compared to normal-hearing ones.Methods: Seventeen hearing-impaired students in 4th year of primary exceptional schools in Karaj, Robatkarim and Shahriyar, Iran, were enrolled in this cross-sectional study. Seventeen normal-hearing students were randomly selected from ordinary schools next to exceptional ones as control group. They were compared for different levels of reading comprehension using the international standard booklet (PIRLS 2001. Results: There was a significant difference in performance between hearing-impaired and normal- hearing students in different levels of reading comprehension (p<0.05.Conclusion: Hearing loss has negative effects on different levels of reading comprehension, so in exceptional centers, reconsideration in educational planning in order to direct education from memorizing to comprehension and deeper layers of learning seems necessary.

Azam Sharifi

2011-12-01

130

Revalence of Hearing Loss and the Related Factors in BuAli Hospital  

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Full Text Available Objective:Determining the prevalence of hearing loss and correlated factors in clients referring to audiology clinic of Buali hospital. Method and Material: This cross-sectional analytic-descriptive survery was carried out on six thousand and twenty ears of 3010 clients (1651 ,a;e amd 1359 female in Audiology clinic of Buali hospital , during Sept 2000 to Sept 2001. Results: Hearing loss is the most common reason for referring the clients (20.5%. 1319 ears (21.9% Showed sensorineural hearing impairment and conductive and mixed hearing loss are observed in 1059 (17.6% and 234 (3.9% ears, respectedly. Hearing loss degree most cases is mild (14% in both ears. There is no significant difference between male and female hearing threshold means (p>0.05 ‘ but a significant difference between hearing thresholds is observed in terms of age (p<0.05. Audiogram configuration in most cases is flat (55.1%. Otoscopic examination reveals abnormal condition in 2333 ears (38.8% . 37.2% of the studied cases have abnormal tympanogram mostly type B (15.9%. 2.2% of the clients wear hearing aid that mostly have B.T.E ones (1.5%. 6.2% of the clients , depends on their hearing impairment type and degree need rehabilitation services. Conclusion: The results are Valid only in the context of this study and it’s generaliztion needs further researches.

Shohreh Jalaei

2004-06-01

131

38 CFR 20.717 - Rule 717. Loss of hearing tapes or transcripts-motion for new hearing.  

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...transcripts-motion for new hearing. 20.717 Section 20...APPEALS: RULES OF PRACTICE Hearings on Appeal § 20.717 Rule 717. Loss of hearing tapes or transcriptsâmotion...equipment failure or other cause, or the official...

2010-07-01

132

Sudden hearing loss: Our experience in treatment with vasoactive therapy  

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Full Text Available Introduction A specific title "sudden hearing loss" refers to illness which is characterized by a sudden, rapid sensoneural hearing loss mostly in one ear without obvious causes, accompanied with dizziness, and without vestibular symptomatology. It is defined as a hearing loss for more than 30 dB on 3 or more successive frequencies which appear in 72 hours. Objective The main goal of our paper was to estimate success of implementation of vasoactive method in patients with sudden hearing loss of senso-neural type in different ranges in hospital conditions. METHOD Our research covered 37 patients hospitalized because of a sudden hearing loss of sensoneural type in different ranges. Diagnosis, in all patients, was established by clinical ORL examination, audiology and vestibular examination. R including CT and MR, neurological, internist and laboratory examinations were used in order to exclude other aetiology. In monitored patients, we started treatment with vasoactive therapy, ampules of xanthinol nicotinate (one ampule of 2 ml, 300 mg or ampules of pentoxiphylline (one ampule of 5 ml, 100 mg in form of infusions with addition of vitamins with an everyday gradual increase of dosage up to 12 ampules of xanthinol nicotinate and up to 5 ampules of pentoxiphylline. Then we started with an everyday decrease of dosage down to the first one. Results After the complete curing protocol, we found out that in patients with light and medium senso-neural damages of hearing sense (23 or 62%, hearing recovery was complete. In patients with heavy damage of hearing (9 or 24%, partial success was evidenced. The most difficult cases, with complete hearing loss, heavy buzzing and vertiginous problem (5 or 14% responded to therapy, so buzzing and vertiginous problems disappeared but hearing was not improved. Conclusion Usage of vasoactive medicaments in hospital conditions in treatment of sudden hearing loss gives good results and it is the closest to aetiological therapy. .

Živi? Ljubica

2008-01-01

133

Long-term cost-effectiveness of screening strategies for hearing loss  

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Full Text Available Routine hearing screening can identify patients who are motivated to seek out and adhere to treatment, but little information exists on the cost-effectiveness of hearing screening in a general population of older veterans. We compared the cost-effectiveness of three screening strategies (tone-emitting otoscope, hearing handicap questionnaire, and both together against no screening (control group in 2,251 older veterans. The effectiveness measure for each group was the proportion of hearing aid use 1 year after screening. The audiology cost measure included costs of hearing loss screening and audiology care for 1 year after screening. Incremental cost-effectiveness was the audiology cost of additional hearing aid use for each screening group compared with the control group. The mean total audiology cost per patient was $77.04, $122.70, $121.37, and $157.08 for the control, otoscope, questionnaire, and dual screening groups, respectively. The tone-emitting otoscope appears to be the most cost-effective approach for hearing loss screening, with a significant increase in hearing aid use 1 year after screening (2.8% and an insignificant incremental cost-effectiveness of $1,439.00 per additional hearing aid user compared with the control group. For this population of older veterans, screening for hearing loss with the tone-emitting otoscope is cost-effective.

Chuan-Fen Liu, PhD, MPH

2011-03-01

134

Profile and Stability of Sensorineural Hearing Loss in Persistent Pulmonary Hypertension of the Newborn.  

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This study found that 19 of 51 infants with persistent pulmonary hypertension of the newborn were diagnosed with sensorineural hearing loss, an incidence 25 times greater than that of intensive care unit infants in general. Treatment durations with mechanical ventilation were significantly longer for the hearing-impaired group compared to the…

Walton, Joseph P.; Hendricks-Munoz, Karen

1991-01-01

135

Disacusia neurossensorial imunomediada / Immunomediated sensorineural hearing loss  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese A disacusia neurossensorial imunomediada (DNSI) é caracterizada geralmente por uma disacusia neurossensorial bilateral, progressiva e assimétrica, acompanhada ou não por outros sintomas da orelha interna. Três pacientes com DNSI cujo quadro clínico e audiométrico eram sugestivos de doença auto-imune [...] , e apresentaram resposta positiva à terapia imunossupressora ou pesquisa positiva de anticorpo anti hsp-70 68kD, foram estudados com relação às características clínicas, testes diagnósticos, alternativas terapêuticas e evolução da doença. Dois pacientes apresentaram quadro de disacusia neurossensorial rapidamente progressiva, associado a quadro vestibular, e outro, quadro de surdez súbita unilateral. Nenhum paciente apresentou positividade às provas reumatológicas, e apenas um paciente apresentou aumento na velocidade de hemossedimentação. Nenhum paciente obteve resposta adequada sustentada à corticoterapia, mas dois deles melhoraram com outras terapias imunossupressoras. O diagnóstico da DNSI é clínico e baseado na resposta positiva ao teste terapêutico com imunossupressores. A pesquisa de anticorpo anti-hsp70 de 68 kD pelo Western Blot é o único exame laboratorial específico para seu diagnóstico, possuindo sensibilidade de 42% e especificidade de 90%. Apenas 1 paciente apresentou positividade para este teste e não respondeu à terapia imunossupressora. Os dois pacientes com teste negativo responderam satisfatoriamente ao tratamento. A baixa sensibilidade do Western Blot e seu alto custo dificultam sua difusa utilização em nosso meio. A introdução precoce do tratamento é de suma importância por auxiliar no diagnóstico e por proporcionar um melhor prognóstico auditivo. Abstract in english The immunomediated sensorineural hearing loss (ISHL) is characterized as an asymmetric and progressive sensorineural hearing loss. Tree patients with ISHL were studied, regarding clinical aspects, diagnostic tests, treatment options and disease evolution. They presented whether positive response to [...] immunosuppressive therapy or positiviness to Western Blot test for hsp 70-68kD. Two patients presented rapidly progressive sensorineural hearing loss, associated to vestibular symptoms and the other presented unilateral sudden deafness. No patient reacted to rheumatological testes, and one presented increased erythrocyte sedimentation rate. None satisfactorily responded to corticotherapy, but two presented clinical improvement with other immunosuppressive therapies. The ISHL diagnosis is based on clinical aspects and on the positive response to therapeutic testes with immunosupressor drugs. The Western Blot test for hsp 70-68 kD, with 42% sensitivity and 90% specificity, is the only specific laboratorial exam for ISHL. One patient presented positiviness to this exam and did not responded to immunosuppressive therapy. Two patients with negative tests satisfactorily responded to immunosuppressive therapy. The low sensitivity and high costs of Western Blot test represent difficulties to the spread use of it. The early introduction of treatment has a major importance in the diagnosis of ISHL and to increase the auditory prognosis.

Norma de Oliveira, Penido; Mariana Dantas, Aumond; Fernando Danelon, Leonhardt; Carlos Eduardo Cesário de, Abreu; Ronaldo Nunes, Toledo.

136

Infants and Children with Hearing Loss Need Early Language Access  

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Around 96 percent of children with hearing loss are born to parents with intact hearing,1 who may initially know little about deafness or sign language. Therefore, such parents will need information and support in making decisions about the medical, linguistic, and educational management of their child. Some of these decisions are time-sensitive and irreversible and come at a moment of emotional turmoil and vulnerability (when some parents grieve the toss of a normally hearing child).2 Clinic...

Kushalnagar, Poorna; Mathur, Gaurav; Moreland, Christopher J.; Napoli, Donna Jo; Osterling, Wendy; Padden, Carol; Rathmann, Christian

2010-01-01

137

Hearing Loss and Older Adults’ Perceptions of Access to Care  

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We investigated whether hard-of-hearing older adults were more likely to report difficulties and delays in accessing care and decreased satisfaction with healthcare access than those without hearing loss. The Wisconsin Longitudinal Study (2003–2006 wave, N = 6,524) surveyed respondents regarding hearing, difficulties/delays in accessing care, satisfaction with healthcare access, socio-demographics, chronic conditions, self-rated health, depression, and length of relationship with provider/s...

Pandhi, Nancy; Schumacher, Jessica R.; Barnett, Steven; Smith, Maureen A.

2011-01-01

138

Clinical study on unilateral hearing loss in children  

International Nuclear Information System (INIS)

A series of 60 children was studied (aged 0 to 10 years, 32 boys, 28 girls) with severe unilateral sensorineural hearing loss of unknown etiology. There were two peaks, at 0 and 6 years. In 19 children, hearing loss was identified during a conservative general health checkup for school or preschool children. In 21 children aged 0 years, 16 were suspected of hearing loss by newborn hearing screening. Temporal bone computed tomography scans were examined in 51 patients. Sixteen ears (31.4%) with hearing loss had inner ear and/or internal auditory canal abnormalities. In one patient, the anomaly was the presence of a bony wall dividing the internal auditory canal into two separate compartments associated with severe inner ear hypoplasia. Two patients had a common cavity. In one of these patients, the anomaly was revealed because of severe bacterial meningitis, and another was detected by newborn hearing screening. Six patients had a narrow internal auditory canal, 4 had a narrow internal auditory canal and hypoplastic cochlea, and 1 had a narrow internal auditory canal and cystic vestibule, and lateral semicircular canal dysplasia. Two patients had a cystic vestibule and lateral semicircular canal dysplasia. One case showed fluctuation of the hearing level in the contralateral ear with normal hearing during the observation period at an average of 20 months. The number of children whose unilateral hearing loss is detected early by newborn hearing screening has enormously increased. Strategies for follow-up, early intervention, and support for families are necessary for young children with unilateral hearing impairment. (author)

2007-01-01

139

Does Unilateral Hearing Loss Lead To Learning Handicap?  

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Full Text Available Hearing loss, even when limited to 1 ear, has been indicated as a handicap to communication and learning. Although this does not seem true based on my clinical impressions, there are no objective data available to evaluate, or even infer, what type of hearing loss can become a true handicap to overall academic achievement. Presented herein are findings that imply, although do not prove, the potential academic handicap of unilateral hearing loss. This study prospectively analyzed the audiologic and otologic screening tests in a university over a 9-year period. The University of Tokyo is one of the leading universities in Japan; the students examined undoubtedly had academic ability well above average, for the entrance examination is one of the most difficult to pass in Japan. The potential handicap to academic achievement caused by hearing impairment was evaluated by comparing the prevalence of hearing impairment among the study population.

Gita Movalleli

2000-05-01

140

Sensorineural hearing loss in Lassa fever: two case reports  

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Full Text Available Abstract Introduction Lassa fever is an acute arena viral haemorrhagic fever with varied neurological sequelae. Sensorineural hearing loss is one of the rare complications which occur usually during the convalescent stage of the infection. Case presentation The cases of two female patients aged 19 and 43 years old, respectively, with clinical features suggestive of Lassa fever and confirmed by immunoserological/Lassa-virus-specific reverse transcriptase polymerase chain reaction are presented. Both patients developed severe sensorineural hearing loss at acute phases of the infections. Conclusion Sensorineural hearing loss from Lassa fever infections can occur in both acute and convalescent stages and is probably induced by an immune response.

Okokhere Peter O

2009-01-01

 
 
 
 
141

A Fanconi Anemias Pationt with Bilateral Totall Hearing Loss  

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Full Text Available Background: Fanconi anemia (FA is an autosomal recessive genetic disorder wich characterized by progressive pancytopenia, multiple congenital anomalies, increased susceptibility to acute myelogenous leukemia and epithelial cancers specially in head and neck and GUT. Characteristic feature of FA include short stature, café-au-laitspots, small eyes, mental retardation, skeletal and ear anomalies.Case: A 23-year-old man who was a known case of FA since he was ten reffered to audiology clinic because of severe hearing loss. His initial diagnosis was pneumonia. Audilogic evaluation revealed bilateral profound hearing loss. Conclusion: One of the anomalies in FA are ear anomalies. These included conductive haering loss, external auditory canal stenosis and auricular malformation and progressive sensoryneural hearing loss. In this report external auditory canal and tympanic membrane were normal. The result of tympanometry were type An and audiometry were bilateral profound hearing loss that is a rare finding in FA patient.

Dr. Seyed Moosa Sadr Hoseyni

2009-12-01

142

Pseudoexfoliation Syndrome and Sensorineural Hearing Loss  

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Full Text Available Introduction: Pseudoexfoliation syndrome (PXS occurs due to the deposition of extracellular fibrillar materials on the anterior chamber of the eye. This syndrome has been considered to be part of a systemic disease with the potential involvement of the inner ear called sensoroneural hearing loss (SNHL.  In this study, we aimed on evaluating SNHL within PXS patients in Iran to compare them with other international reports. Materials and Methods: In total, 33 patients with PXS and 33 age and sex matched controls were enrolled prospectively in a case-control study. Both groups underwent complete ophthalmologic and otorhinolaryngologic examinations and pure tone audiometry (PTA testing. Six frequencies (0.25, 0.5, 1, 2, 3, 4 and 6 KHz were evaluated for PTA in the same ethnic group in order to select the case and control individuals. Data were analyzed using t-test and chi-square test. Results: Forty-nine out of 66 ears (75.2% in the PXS group and 27 ears (40.9% in the control group had SNHL (P

Ramin Zojaji

2011-03-01

143

Genetics of hearing loss: focus on DFNA2  

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Full Text Available Laura M Dominguez, Kelley M DodsonDepartment of Otolaryngology, Head and Neck Surgery, Virginia Commonwealth University, Richmond, VAAbstract: The purpose of this review is to assess the current literature on deafness nonsyndromic autosomal dominant 2 (DFNA2 hearing loss and the mutations linked to this disorder. Hearing impairment, particularly nonsyndromic hearing loss, affects multiple families across the world. After the identification of the DFNA2 locus on chromosome 1p34, multiple pathogenic mutations in two genes (GJB3 and KCNQ4 have been reported. The overwhelming majority of pathogenic mutations linked to this form of nonsyndromic hearing loss have been identified in the KCNQ4 gene encoding a voltage-gated potassium channel. It is believed that KCNQ4 channels are present in outer hair cells and possibly inner hair cells and the central auditory pathway. This form of hearing loss is both phenotypically and genetically heterogeneous and there are still DFNA2 pedigrees that have not been associated with changes in either GJB3 or KCNQ4, suggesting that a possible third gene exists at this locus. Further studies of the DFNA2 locus will lead to a better understanding of progressive hearing loss and provide a better means of early detection and treatment.Keywords: deafness nonsyndromic autosomal dominant 2, nonsyndromic deafness, genetic hearing loss, GJB3, KCNQ4

Dominguez LM

2012-10-01

144

Tone Decay and Hearing Threshold Level in Sensorineural Loss  

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The Bekesy and Rosenberg procedures were used to investigate whether tone decay varies systematically as a function of the initial hearing threshold level of the test tone in sensorineural loss. Tone decay tended to increase with increased hearing threshold level for both tests at all three frequencies used. (Author/KW)

Doehring, Donald G.; Swisher, Linda P.

1971-01-01

145

Effective Practices in Teaching Indigenous Students with Conductive Hearing Loss  

Science.gov (United States)

Hearing impairment due to conductive hearing loss can have a devastating effect on children's language development, and consequently educational outcomes, especially for Indigenous students, for whom there may be the additional issue of being educated in their second or third language. With appropriate interventions, however, Indigenous students…

Partington, Gary; Galloway, Ann

2005-01-01

146

Epistemics in audiological consultations : Divergent conceptualizations of 'hearing' in healthcare encounters between hearing aid acoustitians and patients with hearing loss  

DEFF Research Database (Denmark)

Adult-onset hearing loss affects more than 20% of citizens in the US and in the EU. This second most frequent disability (World Health Organization 2001) is mostly due to aging and noise exposure ('sensorineural'). Although usage of hearing aids effectively increases life quality (Joore et al. 2003; Anteunis 2002), in many western countries, only 15% of those who could benefit from this technology use it, e.g. in the USA, Switzerland, and Finland (Bisgaard 2009). Technological innovation has not helped improve uptake. A longitudional interview study indicates that one barrier to hearing aid acceptance seems to lie in healthcare interactions: 88% of patients with hearing loss accessing the German healthcare system do not complete rehabilitation; the average time between first diagnosis and use of hearing aids is 8-10 years (Meis & Gabriel 2006). The present study contributes to an emering body of CA work on healthcare encounters with hearing loss which show that communication problems occur frequently between healthcare professionals and patients (e.g. Skelt 2006, Laakso 2011-2014, Ruusuvuori 2011-2014; Brouwer 2012, Heinemann et al. 2012, Egbert 2013). The presentation, based on 12 hours of naturally-occurring, video-taped audiological interactions in German, focuses on a specific communication problem which is due to an asymmetricity in "epistemic domains" (Stivers & Rossano 2010:8) in that divergences in the professional's and the patients' conceptualizations of hearing emerge and are frequently not resolved. The goal of these audiological consulations is to select and fit the best possible hearing aid for clients with hearing loss. In order to achieve this goal, audiologists routinely rely on their technological and medical knowledge, the results of a pure-tone audiogram, and the clients' subjective descriptions of hearing experiences in different environments. In these consultations, the institutional conceptualization of hearing (and thus of hearing loss) is that of an objectively measurable functioning of the ear, categorized in an audiogram by decibels and hertz. In contrast, persons with hearing loss perceive of their hearing, even during audiograms, as less precise and more varied. When asked by the audiologist about hearing experiences in different settings (e.g. dyadic conversation, multiperson interaction, telephone, outdoors, train station), the descriptions by clients are diffuse, broad, and metaphorical. Compared to visual impairment, describing hearing seems to be more difficult, and frequently, persons with hearing impairment resort to visual metaphors. A CA examination of conversational order in the areas of turn-taking, sequence, repair, topic, multimodality, and linguistic resources yields partial results for these audiological data, and including epistemics in the analysis achieves to 'grasp' the phenomenon more fully. CA research "into epistemics focuses on the knowledge claims that interactants assert, contest and defend in and through turns-at-talk and sequences of interactionâ? (Heritage 2013:370). Given that the audiologist and the patient frequently do not achieve a shared knowledge of the patient's hearing loss, these institutional encounters appear to be highly problematic in that the imbalance is not resolved. â??(W)hen a speaker indicates that there is an imbalance of information between speaker and hearer, this indication is sufficient to motivate and warrant a sequence of interaction that will be closed when the imbalance is acknowledged as equalized for all practical purposesâ? (Heritage 2012: 32). The presentation concludes with connecting the interactional problems at the micro-level of direct healthcare encounters to the macro-level and globel problems of the impact of untreated hearing loss. The social repercussions are stigmatization, miscommunication, loss of work, social isolation, depression, and suicide (Carmen 2001). The financial loss per person dropping out of work due to hearing loss is estimated at 200,000 US Dollars (World Health Organization 2001). In Europe, t

Egbert, Maria

147

Cigarette smoking, passive smoking, alcohol consumption, and hearing loss.  

Science.gov (United States)

The objective of this large population-based cross-sectional study was to evaluate the association between smoking, passive smoking, alcohol consumption, and hearing loss. The study sample was a subset of the UK Biobank Resource, 164,770 adults aged between 40 and 69 years who completed a speech-in-noise hearing test (the Digit Triplet Test). Hearing loss was defined as speech recognition in noise in the better ear poorer than 2 standard deviations below the mean with reference to young normally hearing listeners. In multiple logistic regression controlling for potential confounders, current smokers were more likely to have a hearing loss than non-smokers (odds ratio (OR) 1.15, 95 % confidence interval (CI) 1.09-1.21). Among non-smokers, those who reported passive exposure to tobacco smoke were more likely to have a hearing loss (OR 1.28, 95 %CI 1.21-1.35). For both smoking and passive smoking, there was evidence of a dose-response effect. Those who consume alcohol were less likely to have a hearing loss than lifetime teetotalers. The association was similar across three levels of consumption by volume of alcohol (lightest 25 %, OR 0.61, 95 %CI 0.57-0.65; middle 50 % OR 0.62, 95 %CI 0.58-0.66; heaviest 25 % OR 0.65, 95 %CI 0.61-0.70). The results suggest that lifestyle factors may moderate the risk of hearing loss. Alcohol consumption was associated with a protective effect. Quitting or reducing smoking and avoiding passive exposure to tobacco smoke may also help prevent or moderate age-related hearing loss. PMID:24899378

Dawes, Piers; Cruickshanks, Karen J; Moore, David R; Edmondson-Jones, Mark; McCormack, Abby; Fortnum, Heather; Munro, Kevin J

2014-08-01

148

Loudness perception affected by early age hearing loss.  

Science.gov (United States)

Tinnitus and hyperacusis, commonly seen in adults, are also reported in children. Although clinical studies found children with tinnitus and hyperacusis often suffered from recurrent otitis media, there is no direct study on how temporary hearing loss in the early age affects the sound loudness perception. In this study, sound loudness changes in rats affected by perforation of the tympanic membranes (TM) have been studied using an operant conditioning based behavioral task. We detected significant increases of sound loudness and susceptibility to audiogenic seizures (AGS) in rats with bilateral TM damage at postnatal 16 days. As increase to sound sensitivity is commonly seen in hyperacusis and tinnitus patients, these results suggest that early age hearing loss is a high risk factor to induce tinnitus and hyperacusis in children. In the TM damaged rats, we also detected a reduced expression of GABA receptor ? and ?6 subunits in the inferior colliculus (IC) compared to the controls. Treatment of vigabatrin (60 mg/kg/day, 7-14 days), an anti-seizure drug that inhibits the catabolism of GABA, not only blocked AGS, but also significantly attenuated the loudness response. Administration of vigabatrin following the early age TM damage could even prevent rats from developing AGS. These results suggest that TM damage at an early age may cause a permanent reduction of GABA tonic inhibition which is critical towards the maintenance of normal loudness processing of the IC. Increasing GABA concentration during the critical period may alleviate the impairment in the brain induced by early age hearing loss. PMID:24747532

Sun, Wei; Fu, Qiang; Zhang, Chao; Manohar, Senthilvelan; Kumaraguru, Anand; Li, Ji

2014-07-01

149

Living with Hearing and Vision Loss Due to Usher Syndrome  

Medline Plus

Full Text Available ... Hearing and Vision Loss Due to Usher Syndrome Video NARRATOR 1: A woman with short gray hair. ... Peck has Usher Syndrome. In this series of videos, she tells her story about overcoming some of ...

150

Living with Hearing and Vision Loss Due to Usher Syndrome  

Medline Plus

Full Text Available ... to Your Employer Know Your Rights Training Resources Workplace Technology CareerConnect Stories ... Support Personal Stories Living with Hearing and Vision Loss Due to Usher Syndrome Living ...

151

Hearing loss from gun and railroad noise--relations with ISO standard 1999.  

Science.gov (United States)

Pure-tone hearing thresholds and anamnestic data pertaining to nosocusis and exposure to gun noise were analyzed for 9778 male railroad train-crew workers. A major portion of losses in hearing sensitivity due to railroad noise are obscured in comparisons of hearing levels of trainmen with the hearing levels of the unscreened samples of United States males given in Annex B, ISO 1999 [ISO 1999 (1990), "Acoustics--Determination of occupational noise exposure and estimation of noise-induced hearing impairment" (International Organization for Standardization, Geneva)]. Comparisons of the hearing levels, adjusted for nosocusis, of trainmen who had used no guns, with the hearing levels of otologically and noise screened males (Annex A, ISO 1999) reveal significant losses due to railroad noise. Additional losses were found at high frequencies in trainmen who had used guns. It appears that the effective Leq8h exposure level of trainmen to railroad noise is about 92 dBA, and 87-89 dBA to gun noise. These results are in general agreement with those of study of railway workers by Prosser et al. [Br. J. Audiol. 22, 85-91 (1988)]. Asymmetries in losses between the two ears, effects of ear protection, losses from nosocusis, and losses from sport, as compared to military, gun noise exposures, are examined. PMID:1787253

Kryter, K D

1991-12-01

152

Postnatal risk factors associated with hearing loss among high-risk preterm infants: tertiary center results from Turkey.  

Science.gov (United States)

The aim of this study was to determine the postnatal risk factors associated with hearing loss as well as the prevalence of hearing loss among high-risk preterm infants in newborn hearing screening (NHS). We performed a retrospective study of high-risk preterm infants born with a gestational age ?32 weeks and/or a birth weight ?1,500 g. A NHS procedure was performed by automated auditory brainstem response (AABR) and automated evoked otoacoustic emission (TEOAE). Infants who failed TEOAE or AABR or both tests were referred to a tertiary audiology center for diagnosis confirmation and management. Postnatal risk factors associated with hearing loss were evaluated and compared for preterm infants with and without hearing loss. 1,360 high-risk preterm infants were assessed. Permanent hearing loss was found in 19 (1.4%) infants. Multivariate analysis revealed that proven sepsis (p = 0.019), mechanical ventilation ?5 days (p = 0.024), loop diuretics (p = 0.001), patent ductus arteriosus ligation (p = 0.018) and operation for retinopathy of prematurity (ROP) (p = 0.034) were significant related factors for the hearing loss. This study showed a low prevalence of hearing loss and an association between operation for ROP and hearing loss in preterm infants, which has not been defined previously. Our results suggest that every neonatal intensive care unit should determine their own risk factors and take precautions to prevent hearing loss for these high-risk preterm infants. PMID:23917736

Eras, Zeynep; Konukseven, Ozlem; Aksoy, Hatice Tatar; Canpolat, Fuat Emre; Genç, Aydan; Sakrucu, Evrim Durgut; Develio?lu, Omer; Dilmen, Ugur

2014-06-01

153

Automatic hearing loss detection system based on auditory brainstem response  

International Nuclear Information System (INIS)

Hearing loss is one of the pathologies with the highest prevalence in newborns. If it is not detected in time, it can affect the nervous system and cause problems in speech, language and cognitive development. The recommended methods for early detection are based on otoacoustic emissions (OAE) and/or auditory brainstem response (ABR). In this work, the design and implementation of an automated system based on ABR to detect hearing loss in newborns is presented. Preliminary evaluation in adults was satisfactory

2007-11-01

154

Annual rate of hearing loss falls after fractionated stereotactic irradiation for vestibular schwannoma  

International Nuclear Information System (INIS)

Purpose: The rate of hearing loss in a population before and after irradiation was investigated to determine the effect of irradiation on hearing impairment. Methods and materials: In 72 patients with vestibular schwannoma who received fractionated stereotactic irradiation from 1992 to 1999, 21 had had their hearing levels examined 3 months or more before the treatment. The mean time between the initial examination and treatment was 18.6 months (range: 3-89 months), and the mean time between treatment and the last follow-up was 24.2 months (12-69 months). Thirty-six to 50 Gy in 20-25 fractions over 5 to 6 weeks was given using an X-ray beam from a linear accelerator. Pure tone average (PTA) was measured using the mean hearing level at five frequencies, and the annual rate of hearing loss was defined as [(hearing loss in PTA(dB))/(follow-up period (months)x12)]. Results: The actual cumulative curve of decrease in tumor size of 2 mm or more was 38.3% at 2 years and 80.0% at 3 years. The mean of hearing loss in PTA was 11.6±10.3 dB (-1 to 35 dB) from the initial examination to the start of irradiation and 11.9±14.4 dB (-14 to 37 dB) from the start of irradiation to the last follow-up. The mean annual rates of hearing loss before irradiation and in the 1st, 2nd, 3rd and 4th years after irradiation were, respectively, 18.6, 11.2, 6.2, 5.1, and 5.0 dB/year. The annual rates of hearing loss in the 2nd year (P=0.025) and 3rd year (P=0.018) were significantly slower than the rate before irradiation. Conclusions: The mean annual rate of hearing loss was higher before irradiation than after irradiation, and hearing loss slowed rather than accelerated after irradiation. Although hearing loss after the treatment was usually permanent, fractionated stereotactic irradiation was suggested to be effective to lower the rate of hearing loss

2001-07-01

155

Prevalence of Hearing Loss in Newborns Admitted to Neonatal Intensive Care Unit  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction: Hearing is essential for humans to communicate with one another. Early diagnosis of hearing loss and intervention in neonates and infants can reduce developmental problems. The aim of the present study was to assess the prevalence of hearing impairment in newborns admitted to a neonatal intensive care unit (NICU and analyze the associated risk factors.   Materials and Methods: This cross-sectional study was conducted to assess the prevalence of hearing loss in neonates who were admitted to the NICU at Nemazee Hospital, Shiraz University of Medical Sciences between January 2006 and January 2007. Auditory function was examined using otoacoustic emission (OAE followed by auditory brainstem response (ABR tests. Relevant potential risk factors were considered and neonates with a family history of hearing loss and craniofacial abnormality were excluded. For statistical analysis logistic regression, the chi-squared test, and Fisher’s exact test were used.    Results: Among the 124 neonates included in the study, 17 (13.7% showed hearing loss in the short term. There was a significant statistical relationship between gestational age of less than 36 weeks (P=0.013, antibiotic therapy (P= 0.033, oxygen therapy (P=0.04, and hearing loss. On the contrary, there was no significant relationship between hearing loss and use of a ventilator, or the presence of sepsis, hyperbilirubinemia, congenial heart disease, transient tachypnea of newborn, congenital pneumonia, or respiratory distress syndrome.  Conclusion: Auditory function in neonates who are admitted to a NICU, especially those treated with oxygenor antibiotics and those born prematurely, should be assessed during their stay in hospital. The importance of early diagnosis of hearing loss and intervention in these neonates and avoidance of any unnecessary oxygenor antibiotic therapy needs to be further promoted.

Shahnaz Pourarian

2012-03-01

156

Satisfaction of Hearing Aids Users With Hearing Loss of Severe and Deep Degree  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction: It is necessary to analyze the efficiency of the hearing aids use, considering the necessity of enlargement and communication difficulty. Objective: To analyze the satisfaction of adults and elders, users of hearing aids with hearing loss of severe and deep degree, using a questionnaire and searching factors that can difficult the adaptation. Method: A retrospective study of 56 patients, with age group between 18 and 86 years old, hearing loss of severe and deep degree and users of HA by a program of concession of hearing aids, submitted to the questionnaire: "Satisfaction with Amplification in Daily Life". The global average was calculated by sub scale and by question and it was given emphasis to the questions that resulted in best and worse averages. Results: 58,9% were women and 41,1% men, about of 55% of the patients presented hearing loss of severe degree and 45% deep degree. 87,5% referred use major than 8 hours daily. The users believe that the acquisition of the hearing aid was the best option and this aid very much in the speech understanding. They feel themselves trustful and able with the sounding amplification and refer a good service by professionals of the service. The performance to the telephone was the problem found. Conclusion:It was demonstrated high degree of satisfaction in the studied population. The hearing loss degree, as well as the incompatibility of systems between telephone and telecoils and the difficulty in the placement of telephone ate factors that difficult the good performance to the telephone. The accentuated hearing loss collaborate for the hearing aid be an integral part of the daily life and essential in the aid to the communication. ACTRN12610000424000

Lessa, Alexandre Hundertmarck

2010-09-01

157

Prevalence of noise-induced hearing loss in drivers  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction: Work-related hearing loss is one of the most common occupational illness progresses over the years of noise exposure associated with the work environment, may cause damage to undertake physical activity, the individual's physiological and mental besides causing hearing damage irreversible interfering with communication and quality of life. With high prevalence of male evaluates which is the second leading cause of hearing loss. Since there is no medical treatment for this type of hearing loss, it is evident the importance of preventive and conferences aimed at preserving hearing and health as a whole. Objective: To assess the prevalence of hearing loss in audiometry admission of drivers. Methods: Retrospective study. By 76 charts of professional drivers in leased transport companies. We analyzed data from specific interview and pure tone audiometry. Results: The prevalence of abnormal tests was 22.36% with the lowest thresholds for tritonal average of 3,000, 4,000 and 6,000 Hz. The higher the age, the higher thresholds. Conclusion: This study has highlighted the occurrence of hearing in the absence of complaints. Considering that PAIR is preventable, justifies the importance of coordinated and multidisciplinary involving not only health teams and safety, but also the institutions involved in preserving the health of workers, as the team SESMET, unions or prosecutors.

Andréa Cintra Lopes1, , , ,

2012-01-01

158

Attenuation of noise-induced hearing loss using methylene blue  

Science.gov (United States)

The overproduction of reactive oxygen species (ROS) and reactive nitrogen species (RNS) has been known to contribute to the pathogenesis of noise-induced hearing loss. In this study, we discovered that in BALB/c mice pretreatment with methylene blue (MB) for 4 consecutive days significantly protected against cochlear injury by intense broad-band noise for 3?h. It decreased both compound threshold shift and permanent threshold shift and, further, reduced outer hair cell death in the cochlea. MB also reduced ROS and RNS formation after noise exposure. Furthermore, it protected against rotenone- and antimycin A-induced cell death and also reversed ATP generation in the in vitro UB-OC1 cell system. Likewise, MB effectively attenuated the noise-induced impairment of complex IV activity in the cochlea. In addition, it increased the neurotrophin-3 (NT-3) level, which could affect the synaptic connections between hair cells and spiral ganglion neurons in the noise-exposed cochlea, and also promoted the conservation of both efferent and afferent nerve terminals on the outer and inner hair cells. These findings suggest that the amelioration of impaired mitochondrial electron transport and the potentiation of NT-3 expression by treatment with MB have a significant therapeutic value in preventing ROS-mediated sensorineural hearing loss.

Park, J-S; Jou, I; Park, S M

2014-01-01

159

Challenges and successes in recruiting firefighters for hearing loss prevention research.  

Science.gov (United States)

Noise-induced hearing loss (NIHL) is a significant occupational health problem in the United States, affecting more than 1 million firefighters. Noise hazards include vehicles, sirens, and power tools. Additionally, firefighters are commonly exposed to ototoxic chemicals. Because the use of hearing protection is not universally required for firefighters, firefighters must be educated about NIHL to ensure they take personal responsibility for hearing loss prevention. This study discusses challenges associated with recruiting firefighters to participate in a randomized, controlled trial testing a web-based hearing protection training program. Successful recruitment strategies included collaboration with key stakeholders, a flexible and convenient computer-based intervention, expansion to multiple recruitment sites, and interactive outreach to potential participants. Future research should use quantitative methods to evaluate and compare the effectiveness of specific recruitment strategies to facilitate firefighter enrollment in research studies. Developing and testing effective hearing protection interventions for firefighters is a crucial first step toward preventing NIHL in this population. PMID:23701004

Hong, OiSaeng; Fiola, Lauren Ann; Feld, Jamie

2013-06-01

160

Word Recognition for Temporally and Spectrally Distorted Materials : The Effects of Age and Hearing Loss  

DEFF Research Database (Denmark)

Objectives: The purpose of Experiment 1 was to measure word recognition in younger adults with normal hearing when speech or babble was temporally or spectrally distorted. In Experiment 2, older listeners with near-normal hearing and with hearing loss (for pure tones) were tested to evaluate their susceptibility to changes in speech level and distortion types. The results across groups and listening conditions were compared to assess the extent to which the effects of the distortions on word recognition resembled the effects of age-related differences in auditory processing or pure-tone hearing loss. Design: In Experiment 1, word recognition was measured in 16 younger adults with normal hearing using Northwestern University Auditory Test No. 6 words in quiet and the Words-in-Noise test distorted by temporal jittering, spectral smearing, or combined jittering and smearing. Another 16 younger adults were evaluated in four conditions using the Words-in-Noise test in combinations of unaltered or jittered speech and unaltered or jittered babble. In Experiment 2, word recognition in quiet and in babble was measured in 72 older adults with near-normal hearing and 72 older adults with hearing loss in four conditions: unaltered, jittered, smeared, and combined jittering and smearing. Results: For the listeners in Experiment 1, word recognition was poorer in the distorted conditions compared with the unaltered condition. The signal to noise ratio at 50% correct word recognition was 4.6 dB for the unaltered condition, 6.3 dB for the jittered, 6.8 dB for the smeared, 6.9 dB for the double-jitter, and 8.2 dB for the combined jitter-smear conditions. Jittering both the babble and speech signals did not significantly reduce performance compared with jittering only the speech. In Experiment 2, the older listeners with near-normal hearing and hearing loss performed best in the unaltered condition, followed by the jitter and smear conditions, with the poorest performance in the combined jitter-smear condition in both quiet and noise. Overall, listeners with near-normal hearing performed better than listeners with hearing loss by similar to 30% in quiet and similar to 6 dB in noise. In the quiet distorted conditions, when the level of the speech was increased, performance improved for the hearing loss group, but decreased for the older group with near-normal hearing. Recognition performance of younger listeners in the jitter-smear condition and the performance of older listeners with near-normal hearing in the unaltered conditions were similar. Likewise, the performance of older listeners with near-normal hearing in the jitter-smear condition and the performance of older listeners with hearing loss in the unaltered conditions were similar. Conclusions: The present experiments advance our understanding regarding how spectral or temporal distortions of the fine structure of speech affect word recognition in older listeners with and without clinically significant hearing loss. The Speech Intelligibility Index was able to predict group differences, but not the effects of distortion. Individual differences in performance were similar across all distortion conditions with both age and hearing loss being implicated. The speech materials needed to be both spectrally and temporally distorted to mimic the effects of age-related differences in auditory processing and hearing loss.

Smith, Sherri L.; Pichora-Fuller, Margaret Kathleen

2012-01-01

 
 
 
 
161

Noise-induced hearing loss and portable radios with headphones.  

Science.gov (United States)

Portable radio/cassette players with headphones have gained increasing popularity in recent years. Volume settings are often increased to override environmental noise, perhaps placing the listener at risk for noise-induced hearing loss (NIHL). A total of 190 public college students in NYC were studied via a self-administered questionnaire regarding the volume setting used and weekly exposure in hours to these units. Three popular models were tested using a Bruel and Kjaer sound level meter, octave band filter and artificial ear. Sound levels were measured at various frequencies (250-8000 Hz) and an overall measurement obtained using the "A"-weighted scale. Based on OSHA criteria for permissible noise dose (i.e. intensity X duration) in the work place, auditory risk criteria were developed. Of all students who used such radios 31.4% equalled or exceeded the maximum allowable dose permitted by these criteria (41.2% of the males and 29.2% of females). This sex-related difference in risk, while not statistically significant, warrants further investigation. Of the total 'at risk' group 50% exceeded the risk criteria by more than 100%. These results suggest that portable radios with headphones may be capable of causing permanent hearing loss in a large proportion of radio users. PMID:4030232

Catalano, P J; Levin, S M

1985-06-01

162

[Sound localization in patients with asymmetrical hearing loss].  

Science.gov (United States)

Good directional hearing ability demands good and symmetrical hearing in both ears. We report the effect of impaired hearing on the directional hearing ability of 98 patients, especially of patients with bilateral asymmetrical hearing loss. The directional testing device included 12 loudspeakers placed at 30 degree intervals in a circle with a diameter of 3.25 m, whose centre lay between the ears of the patient. In included an audiometer for producing the signals, an amplifier and a PDP11/23 computer interfaced to a loudspeaker switch bank. The subject's answers to 60 directionally randomized stimuli were recorded. During the presentation of the signal the patients were not allowed to turn their head. The patients had to name the number of the loudspeaker on the circle that they thought was producing the sound. In addition to the directional hearing test a pure-tone audiogram was done, and the middle- and high-frequency hearing loss estimated. The records of the directional hearing test were analysed in two new ways: firstly, vector analysis of the errors; secondly, averaging of the difference between the true interaural time delay and the virtual time difference, which was implicated in the possibly incorrect answer of the patient (effective delta-t-parameter). This average gives a score for the uncertainty in defining the correct "cone of confusion". In addition to the statistical analysis, two cases are reported showing the directional hearing ability of two patients with neuromas treated by transtemporal surgery, with some residual hearing.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:2030084

Hünig, G; Berg, M

1991-01-01

163

Hearing loss in otitis media with effusion- types and management- a study of hundred cases  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction- Serous Ottis media or otitis media with effusion is a common cause of hearing loss of acute onset. The common presentation will be a block or reduced hearing possible after a travel or flight. Most of the cases present with conductive hearing loss while some may present with mixed or even pure sensory hearing loss. Background- we study hundred patients diagnosed with serous otitis media for the type of hearing loss and characterize the management strategy. Conclusion- Serous otitis media is a common cause of hearing loss which is mostly conductive and is amenable to treatment while some rare cases which may persist may require assistive hearing with amplification. Although sensorineral hearing loss is rare in otitis media, it is seen in practice along with mixed hearing loss. The pathophysiology of the neural affection of hearing loss remains a mystery although many theories exist.

Sriram Nathan

2012-01-01

164

Resolution of Sudden Sensorineural Hearing Loss Following a Roller Coaster Ride  

Digital Repository Infrastructure Vision for European Research (DRIVER)

We report a case of sudden unilateral sensorineural hearing loss of sudden onset during an aeroplane flight, which completely resolved during a roller coaster ride at Alton Towers theme park. A review of the literature concerning sudden idiopathic sensorineural hearing loss and spontaneous resolution are discussed. Initially, pure-tone audiometry showed a profound sensorineural hearing loss in the right ear and mild sensorineural hearing loss in the left ear (of note, the hearing was normal p...

Kumar, Aman; Sinha, Amrita; Al-waa, Ahmad M.

2011-01-01

165

78 FR 53700 - Revised Medical Criteria for Evaluating Hearing Loss and Disturbances of Labyrinthine-Vestibular...  

Science.gov (United States)

...criteria in our Listing of Impairments (listings) for evaluating hearing loss and disturbances...Criteria for Evaluating Hearing Impairments and Disturbance of Labyrinthine-Vestibular...Policy Conference on Hearing Impairments and [[Page...

2013-08-30

166

Validity of hearing thresholds obtained from the rising portion of the audiogram in sensorineural hearing loss.  

Science.gov (United States)

Two experiments were performed for this study. The purpose of both experiments was to examine the validity of pure-tone hearing thresholds obtained near the rising portion of a sensorineural hearing loss. Recent work by other investigators has suggested that thresholds obtained near the rising portion of the audiogram may not correspond to the severity of damage at the cochlear place associated with the test frequency. In the first experiment this issue was addressed in 11 subjects having low-frequency sensorineural hearing loss, whereas 12 subjects (19 ears) having notch-shaped high-frequency sensorineural hearing losses were examined in the second experiment. The results indicated that thresholds obtained from the rising portion of the audiometric configuration were, in most instances, determined by sensitivity at test frequency. An exception to this generalization involved low-frequency sensorineural hearing loss with a slope for the rising portion of the audiogram exceeding -25 dB/octave. In these cases the severity of the loss may be underestimated for test frequencies immediately adjacent to the rising portion of the audiogram. PMID:6738031

Humes, L E; Tharpe, A M; Bratt, G W

1984-06-01

167

Acute unilateral hearing loss as an unusual presentation of cholesteatoma  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Cholesteatomas are epithelial cysts that contain desquamated keratin. Patients commonly present with progressive hearing loss and a chronically discharging ear. We report an unusual presentation of the disease with an acute hearing loss suffered immediately after prolonged use of a pneumatic drill. Case presentation A 41 year old man with no previous history of ear problems presented with a sudden loss of hearing in his right ear immediately following the prolonged use of a pneumatic drill on concrete. The cause was found to be a fractured long process of incus which had been eroded by the presence of an attic cholesteatoma. A tympanomastoidectomy and ossiculoplasty was performed with good result. Conclusion Cholesteatomas may be asymptomatic and insidious in their onset. This case illustrates the point that an indolent disease such as this may present in unusual ways and the clinician must always have a high index of suspicion combined with thorough assessment and examination of every patient.

Bickerton Richard C

2005-09-01

168

Wideband Aural Acoustic Absorbance Predicts Conductive Hearing Loss in Children  

Science.gov (United States)

Objective This study tested the hypothesis that wideband aural absorbance predicts conductive hearing loss (CHL) in children medically classified as having otitis media with effusion. Design Absorbance was measured in the ear canal over frequencies from 0.25 to 8 kHz at ambient pressure or as a swept tympanogram. CHL was defined using criterion air-bone gaps of 20, 25 and 30 dB at octaves from 0.25 to 4 kHz. A likelihood-ratio predictor of CHL was constructed across frequency for ambient absorbance and across frequency and pressure for absorbance tympanometry. Performance was evaluated at individual frequencies and for any frequency at which a CHL was present. Study Sample Absorbance and conventional 226-Hz tympanograms were measured in children of age 3 to 8 years with CHL and with normal hearing. Results Absorbance was smaller at frequencies above 0.7 kHz in the CHL group than the control group. Based on the area under the receiver operating characteristic curve, wideband absorbance in ambient and tympanometric tests were significantly better predictors of CHL than tympanometric width, the best 226-Hz predictor. Accuracies of ambient and tympanometric wideband absorbance did not differ. Conclusions Absorbance accurately predicted CHL in children and was more accurate than conventional 226-Hz tympanometry.

Keefe, Douglas H.; Sanford, Chris A.; Ellison, John C.; Fitzpatrick, Denis F.; Gorga, Michael P.

2013-01-01

169

Correlation between hearing loss and the results of the following questionnaires: Hearing Handicap Inventory for the Adults - Screening Version HHIA-S and Hearing Handicap Inventory for the Elderly - Screening Version - HHIE-S  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction: The self-assessment questionnaires are useful to measure the emotional and social/transient consequences resulting from hearing loss, and they can be used in a wide range of situations in the clinical routine, such as auditory screening. Objective: Check the sensitivity and specificities of HHIA-S and HHIE-S questionnaires to identify a hearing loss and their usages in auditory screenings, as well as analyze the ability of these questionnaires to detect different degrees of hearing impairments in the studied people. Method: Retrospective study with 51 individuals aged between 18 and 88, who filled out the Hearing Handicap Inventory for Adults Screening Version - HHIA-S and Hearing Handicap Inventory for the Elderly Screening Version - HHIE-S questionnaires at the waiting room of the Brazilian Unified Health System (SUS's otorhinolaryngology infirmary. Results: The instruments showed a low sensitivity (47%, not identifying individuals with a hearing loss; however, they showed a high specificity (75%, accurately identifying individuals with no hearing disorder. Moreover, no significant association between the degree of hearing loss and the constraint degree for participation was found. Conclusion: the aforementioned questionnaires revealed a low sensitivity and a high specificity, proving to be ineffective for auditory screenings in a group with previous hearing complaints in addition to being unable to detect different types and degrees of hearing impairment.

Menegotto, Isabela Hoffmeister

2011-07-01

170

Intratympanic injection of dexamethasone for treatment of tinnitus in patients with sudden sensorineural hearing loss  

Directory of Open Access Journals (Sweden)

Full Text Available The purpose of this study is to test the effectiveness of intratympanic dexamethasone injections as a treatment for severe tinnitus in idiopathic sudden sensorineural hearing loss (SNHL. We studied 37 patients who received intratympanic dexamethasone injections and 14 control patients who did not receive it, with severe tinnitus after onset of unilateral sudden SNHL. Hearing level did not change during this study in any patient. The relationship between the duration of tinnitus and effectiveness of treatment was investigated in sudden SNHL. We used a visual analogue scale to evaluate 51 patients with severe tinnitus at the stage of stable hearing level after idiopathic sudden sensorineural hearing loss. Forty-one per cent of patients showed significant improvement after treatment. The average period between onset of sudden sensorineural hearing loss and initiation of intratympanic dexamethasone injection was significantly shorter (207 days in the improved group than in the unchanged group (482 days (P<0.001. In control group, one of 14 patients presented significant improvement spontaneously. Intratympanic dexamethasone treatment may be effective in treatment of severe tinnitus after sudden SNHL at the stage of stable hearing level, and the shorter the period from onset of sudden deafness to the start of intratympanic dexamethasone treatment, the greater the improvement in tinnitus that can be expected.

Tsutomu Nakashima

2012-01-01

171

Sensorineural Hearing Loss due to Air Bag Deployment  

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Deployment of the air bag in a passenger vehicle accident rarely causes otologic injuries. However, sensorineural hearing loss induced by air bag deployment is extremely rare, with only a few cases reported in the English literature. A 38-year-old man involved in a traffic accident while driving his car at 40?km/hour presented with right sensorineural hearing loss and tinnitus, without associated vertigo. Pure-tone audiometry demonstrated elevated thresholds of 30?dB and 25?dB at 4?kH...

Ohki, Masafumi; Ishikawa, Jyunichi; Tahara, Atsushi

2012-01-01

172

Frequency of ear symptoms and hearing loss in ichthyosis: a pilot survey study.  

Science.gov (United States)

Ichthyoses comprise a heterogeneous array of skin conditions resulting from impairment of cornification. Although ear structures can be affected, ear-related symptoms have never been investigated in patients with ichthyosis. In this pilot survey study, our aim was to determine the frequency of ear symptoms, hearing loss, and related medical interventions in patients with ichthyosis. Our secondary aim was to compare the frequency of these items according to age group. An online survey using Redcap was developed and posted online on the Foundation for Ichthyosis and Related Skin Types website for 6 months. Patients or parents of patients with ichthyosis were asked to complete the survey. Data analysis excluded patients with keratitis-ichthyosis-deafness syndrome and surveys that had fewer than two completed items. One hundred thirty-five unique surveys were used for data analysis. Of all participants, 80% reported ear pruritus, 66% reported trouble hearing, 29% reported frequent ear pain, 28% had abnormal hearing test results, and 16% had used hearing aids. Of the 88 participants who reported trouble hearing, 24 (27.3%) had never been to a hearing specialist. Significantly more participants older than 18 years of age (74%, 57/77) reported trouble hearing than participants age 18 years and younger (53%, 31/58; p = 0.02). The frequencies of other ear symptoms and hearing loss were not statistically significantly different between the age groups. Ear pruritus, ear pain, and hearing loss are important concerns in patients with all forms of ichthyosis in all age groups. Early diagnosis and intervention may improve the quality of life of patients with ichthyosis. PMID:24601965

Huang, Jennifer T; Mallon, Kaitlin; Hamill, Shannon; Ohlms, Laurie A; Liang, Marilyn G

2014-01-01

173

Sensorineural hearing loss following irradiation to the malignant tumor of the head and neck  

International Nuclear Information System (INIS)

We observed sensorineural hearing loss following X-ray irradiation to the malignant tumor of head and neck. There were 24 patients whose auditory organs lied within the irradiation field. Ten of these patients were affected by sensorineural hearing loss. Hearing loss occurred at a high frequency in elderly patients, epipharynx tumor and high dose of irradiation. Many cases revealed high tone hearing loss. Most cases showed about a 20?30 dB hearing loss, so their impediment seemed not severe in daily life. In some of these cases, we could have temporal bone findings, but there were no particular findings relevant to sensorineural hearing loss. (author)

1989-01-01

174

Occupational noise-induced hearing loss in India  

Directory of Open Access Journals (Sweden)

Full Text Available Noise is the insidious of all industrial pollutants, involving every industry and causing severe hearing loss in every country in the world. Exposure to excessive noise is the major avoidable cause of permanent hearing impairment. Worldwide, 16% of the disabling hearing loss in adults is attributed to occupational noise, ranging from 7 to 21% in the various subregions. The estimated cost of noise to developed countries ranges from 0.2 to 2% of the gross domestic product (GDP. Noise-induced hearing loss (NIHL is bilateral and symmetrical, usually affecting the higher frequencies (3k, 4k or 6k Hz and then spreading to the lower frequencies (0.5k, 1k or 2k Hz. Other major health effects are lack of concentration, irritation, fatigue, headache, sleep disturbances, etc. The major industries responsible for excessive noise and exposing workers to hazardous levels of noise are textile, printing, saw mills, mining, etc. Hearing protectors should be used when engineering controls and work practices are not feasible for reducing noise exposure to safe levels. Earmuffs, ear plugs and ear canal caps are the main types of hearing protectors. In India, NIHL has been a compensable disease since 1948. It is only in 1996 that the first case got compensation. Awareness should be created among workers about the harmful effects of noise on hearing and other body systems by implementing compulsory education and training programs. There are very few published studies of NIHL in India. More extensive studies are needed to know the exact prevalence of NIHL among the various industries in India.

Nandi Subroto

2008-01-01

175

Mechanism study of laser cochleostomy-induced early hearing loss in a rat model.  

Science.gov (United States)

Hearing loss following laser-assisted ear surgery has been reported. However, the mechanism responsible for the hearing loss remains largely speculative. The aim of this study was to investigate the correlation between laser-induced hearing loss and changes in the number of hair cell ribbon synapses and ultrastructure in the cochlea. Laser cochleostomy was performed with a superpulsed carbon dioxide (CO2) laser at 2 and 5 W in Sprague-Dawley rats. Auditory brainstem responses (ABRs) were measured preoperatively and 2 days after surgery. The synapse numbers in apical and middle cochlear turns were quantified. Transmission electron microscopy was employed to further examine the subcellular changes in the cochlea. Click and tonal ABR threshold shifts in both 2 and 5-W groups displayed a frequency-dependent loss within the frequency range measured. Laser cochleostomy induced a significant decrease of synapse numbers in the middle turn in both groups (p?laser-caused hearing loss even under low-energy laser cochleostomy. The high-energy laser-induced hearing loss was associated with more reduction of synapse number. PMID:23912777

Ye, Qing; Geng, Yang; Zhang, Xian-Zeng; Chen, Wen-Lie; Tian, Tian-Jie; Xie, Shu-Sen; Huang, Zheng

2014-03-01

176

Pegylated interferon/ribavirin-associated sudden hearing loss in a patient with chronic hepatitis C in Brazil  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in english Sudden hearing loss is defined as a sensorineural hearing loss, equal to or greater than 30 dB, at three or more consecutive frequencies, which takes place within 72 hours. Both peginterferon and ribavirin are well-known to be associated with significant adverse effects, but sudden hearing loss is u [...] ncommon. We report a 65-year-old male patient who developed sudden-onset hearing loss during combination therapy with pegylated interferon-alpha and ribavirin for chronic hepatitis C. Peginterferon and ribavirin may cause sudden hearing loss that may not recover after discontinuation of therapy. Immediate treatment for all possible etiologies is essential, along with targeted investigations and early referral for an Ear, Nose and Throat specialist. Physicians should be aware of the possible ototoxic effects of peginterferon and ribavirin combination therapy requiring appropriate surveillance.

Maria Cassia Jacintho, Mendes-Corrêa; Roseli Saraiva Moreira, Bittar; Norma, Salmito; Jeanne, Oiticica.

177

Pegylated interferon/ribavirin-associated sudden hearing loss in a patient with chronic hepatitis C in Brazil  

Directory of Open Access Journals (Sweden)

Full Text Available Sudden hearing loss is defined as a sensorineural hearing loss, equal to or greater than 30 dB, at three or more consecutive frequencies, which takes place within 72 hours. Both peginterferon and ribavirin are well-known to be associated with significant adverse effects, but sudden hearing loss is uncommon. We report a 65-year-old male patient who developed sudden-onset hearing loss during combination therapy with pegylated interferon-alpha and ribavirin for chronic hepatitis C. Peginterferon and ribavirin may cause sudden hearing loss that may not recover after discontinuation of therapy. Immediate treatment for all possible etiologies is essential, along with targeted investigations and early referral for an Ear, Nose and Throat specialist. Physicians should be aware of the possible ototoxic effects of peginterferon and ribavirin combination therapy requiring appropriate surveillance.

Maria Cassia Jacintho Mendes-Corrêa

2011-02-01

178

The More the Worse: the Grade of Noise-Induced Hearing Loss Associates with the Severity of Tinnitus  

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Full Text Available Tinnitus disturbs lives and negatively affects the quality of life of about 2% of the adult world population. Research has shown that the main cause of tinnitus is hearing loss. To analyze a possible association of the degree of hearing loss with the severity of tinnitus, we have performed a retrospective study using admission data on 531 patients suffering from chronic tinnitus. We have found that 83% of our tinnitus patients had a high frequency hearing loss corresponding to a noise-induced hearing loss (NIHL. There was a significant correlation between the mean hearing loss and the tinnitus loudness (p < 0.0001. Interestingly, patients suffering from decompensated chronic tinnitus had a greater degree of hearing loss than the patients with compensated form of tinnitus. In addition, we demonstrate that the degree of hearing loss positively correlates with the two subscales (“intrusiveness” and “auditory perceptional difficulties” of the Tinnitus Questionnaire. Our retrospective study provides indirect evidence supporting the hypothesis that the degree of noise-induced hearing loss influences the severity of tinnitus.

Agnieszka J. Szczepek

2010-08-01

179

Hearing loss in the mining industry: overview of the NIOSH hearing loss prevention program at the Pittsburgh Research Laboratory  

Energy Technology Data Exchange (ETDEWEB)

The National Institute for Occupational Safety and Health (NIOSH) has recognised that noise-induced hearing loss (NIHL) is the most common occupational illness in the United States. The Pittsburgh Research Laboratory at NIOSH has developed a hearing loss prevention program for overcoming these respective barriers in an attempt to reduce NIHL in the mining industry. The program is comprised of four key programmatic areas: noise dose/source relationships; availability of effective noise control; worker education and empowerment; and communication issues. 13 refs., 7 figs.

Matetic, R.J. [NIOSH, Pittsburgh, PA (United States)

2005-07-01

180

Sensorineural Hearing Loss Associated with Occupational Noise Exposure: Effects of Age-Corrections  

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Full Text Available Noise-induced permanent threshold shifts (NIPTS were computed from retrospective audiometric analyses by subtracting aging effects on hearing sensitivity in sixty-eight patients with bilateral sensorineural hearing loss who reported significant occupational noise exposure histories. There were significant effects of age on NIPTS but no significant gender- or ear- differences in terms of NIPTS. The NIPTS at 2,000 Hz was found to be significantly greater than NIPTS at frequencies 500 Hz, 1,000 Hz, 4,000 Hz, and 8,000 Hz. Defined noise notches were seen in the audiograms of 38/136 (27% ears with SNHL. Results support models that suggest interactive effects of aging and noise on sensorineural hearing loss in ears with occupational noise exposure.

2009-02-01

 
 
 
 
181

Role of cochlear efferents in noise induced hearing loss.  

Czech Academy of Sciences Publication Activity Database

. Cambridge : NOPHER, 2000, s. 10.[An International Symposium on noise induced hearing loss. Cambridge (GB), 07.07.2000-10.07.2000]Grant CEP: GA ?R GA309/97/0830; GA MZd NK4747Výzkumný zám?r: CEZ:AV0Z5039906Kód oboru RIV: FH - Neurologie, neurochirurgie, neurov?dy

Aran, J. M.; Popelá?, Ji?í; Smith, D. W.

182

Wordlikeness and Word Learning in Children with Hearing Loss  

Science.gov (United States)

Background: The more a novel word conforms to the phonotactics of the language, the more wordlike it is and the easier it is to learn. It is unknown to what extent children with hearing loss (CHL) take advantage of phonotactic cues to support word learning. Aims: This study investigated whether CHL had similar sensitivities to wordlikeness during…

Stiles, Derek J.; McGregor, Karla K.; Bentler, Ruth A.

2013-01-01

183

Effectiveness of Cochlear Implants in Adults with Sensorineural Hearing Loss. Technology Assessment Report.  

Science.gov (United States)

Sensorineural hearing loss is the third leading cause of disability during the adult years, according to the World Health Organization. This type of hearing loss is usually permanent, most commonly occurs gradually, and becomes worse with increasing age w...

G. Raman J. Lau J. Lee J. M. Gaylor M. Chung M. Rao S. Sen

2011-01-01

184

Sensorineural hearing loss and language development following neonatal extracorporeal membrane oxygenation  

Digital Repository Infrastructure Vision for European Research (DRIVER)

OBJECTIVE: To determine the prevalence of hearing loss in school-age children who have undergone neonatal extracorporeal membrane oxygenation (ECMO) treatment and to identify any effects of hearing loss on speech- and language development.

Hondel, D. Den; Madderom, M. J.; Goedegebure, A.; Gischler, S. J.; Mazer, P.; Tibboel, D.; Ijsselstijn, H.

2012-01-01

185

Loudness of brief tones in listeners with normal hearing and sensorineural hearing loss  

DEFF Research Database (Denmark)

To investigate how hearing loss affects the loudness of brief tones, loudness matches between 5- and 200-ms tones were obtained as a function of level. Loudness functions derived from these data indicated that the gain required to restore loudness usually is the same for short and long sounds.

Poulsen, Torben

1997-01-01

186

Prevalence of sensorineural hearing loss in Asian children.  

Science.gov (United States)

The study was designed to assess whether Asian children were at an increased risk of having sensorineural hearing loss. All the Asian children aged between 5 and 16 years were identified from class lists to form the study group, and an equal number of non-Asian children, controlling for age and sex, were randomly selected from the Child Health records to form the control group. With parent's consent, a four frequency (1, 2, 4 and 8 kHz) pure tone screening test was carried out on the children in both groups. There was a second screen for the failures and a diagnostic assessment for those failing again. Prevalence rate was calculated for two categories of hearing impairment (mild-to-profound and moderate-to-profound) and for the better and worse ear, resulting in four prevalence estimates for each group. The absolute prevalence rates for the Asian children were all consistently higher (ranging from 5.09 to 9.61 per 1000) than the non-Asian children (ranging from 1.4 to 3.51 per 1000) and the relative risk measure showed the Asian group to be 2.42-3.61 times at greater risk of having a hearing loss. The results of this study were compared with other studies and inconsistencies were discussed with reference to methodological differences and deficiencies. It was concluded that Asian children were at an increased risk of sensorineural hearing loss. PMID:8922698

Naeem, Z; Newton, V

1996-10-01

187

Cognitive spare capacity in older adults with hearing loss  

Science.gov (United States)

Individual differences in working memory capacity (WMC) are associated with speech recognition in adverse conditions, reflecting the need to maintain and process speech fragments until lexical access can be achieved. When working memory resources are engaged in unlocking the lexicon, there is less Cognitive Spare Capacity (CSC) available for higher level processing of speech. CSC is essential for interpreting the linguistic content of speech input and preparing an appropriate response, that is, engaging in conversation. Previously, we showed, using a Cognitive Spare Capacity Test (CSCT) that in young adults with normal hearing, CSC was not generally related to WMC and that when CSC decreased in noise it could be restored by visual cues. In the present study, we investigated CSC in 24 older adults with age-related hearing loss, by administering the CSCT and a battery of cognitive tests. We found generally reduced CSC in older adults with hearing loss compared to the younger group in our previous study, probably because they had poorer cognitive skills and deployed them differently. Importantly, CSC was not reduced in the older group when listening conditions were optimal. Visual cues improved CSC more for this group than for the younger group in our previous study. CSC of older adults with hearing loss was not generally related to WMC but it was consistently related to episodic long term memory, suggesting that the efficiency of this processing bottleneck is important for executive processing of speech in this group.

Mishra, Sushmit; Stenfelt, Stefan; Lunner, Thomas; Ronnberg, Jerker; Rudner, Mary

2014-01-01

188

Idiopathic sudden progressive hearing loss and round window membrane rupture.  

Science.gov (United States)

We investigated 24 cases of idiopathic sudden progressive deafness (ISPD) in which worsening of sensorineural hearing loss after initial examination was confirmed by audiometry. Exploratory tympanotomy was performed in 10 of 24 patients, and revealed perilymphatic leak in 4 patients. However, there was a higher incidence and a more severe degree of vertigo and imbalance in the group that was operated on than in the non-operated group. Our study has shown that there was no clear difference in the degree of hearing improvement between the operated group and the conservatively treated group. In both of these groups, an abruptly falling audiometric configuration was frequently found in the audiogram obtained at the stage of fixed hearing perception, suggesting the possibility that both groups may have a common lesion at the basal turn of the cochlea. PMID:3753291

Kanzaki, J

1986-01-01

189

Combined Intratympanic and Systemic Steroid Therapy for Poor-Prognosis Sudden Sensorineural Hearing Loss  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction: The aim of this study was to evaluate the efficacy of combined intratympanic and systemic steroid therapy compared with systemic steroid therapy alone in idiopathic sudden sensorineural hearing loss (ISSNHL patients with poor prognostic factors.     Materials and Methods: Seventy-seven patients with sudden sensorineural hearing loss (SSNHL who had at least one poor prognostic factor (age greater than 40 years, hearing loss more than 70 db, or greater than a 2-week delay between the onset of hearing loss and initiation of therapy were included in this study. Patients were randomized to the intervention group (combined intratympanic and systemic steroid therapy or the control group (systemic steroid therapy alone. All patients received oral treatment with systemic prednisolone (1 mg/kg/day for 10 days, acyclovir (2 g/day for 10 days, divided into four doses, triamterene H (daily, and omeprazole (daily, during steroid treatment, and were advised to follow a low salt diet. The intervention group also received intratympanic dexamethasone injections (0.4 ml of 4 mg/ml dexamethasone two times a week for two consecutive weeks (four injections in total. A significant hearing improvement was defined as at least a 15-db decrease in pure tone average (PTA.  Results: Among all participants, 44 patients (57.14% showed significant improvement in hearing evaluation. More patients showed hearing improvement in the intervention group than in the control group (27 patients (75% versus 17 patients (41.4%, respectively; P = 0.001.  Conclusion:  The combination of intratympanic dexamethasone and systemic prednisolone is more effective than systemic prednisolone alone in the treatment of poor-prognosis SSNHL.

Shima Arastou

2012-12-01

190

Contrast-enhanced MR imaging of the endolymphatic sac in patients with sudden hearing loss  

Energy Technology Data Exchange (ETDEWEB)

Our objective was to evaluate the frequency of contrast enhancement of the endolymphatic sac in patients with sudden hearing loss. Forty consecutive patients with sudden sensorineural hearing loss (20 males and 20 females; age range 11-82 years), 40 age-matched control subjects, and 5 patients with Meniere's disease were examined using the same imaging protocol on a 1.5-T MR system. Pre- and post-contrast-enhanced T1-weighted 3D spoiled gradient-echo sequence (3D SPGR; TR/TE=23/10 ms, no. of excitations=1, flip angle=30 ) images were obtained using a voxel size of 0.6 x 0.7 x 0.8 mm{sup 3}. Contrast enhancement in the area of the endolymphatic sac was assessed by two radiologists, and the frequency of contrast enhancement was compared between the three study groups. Enhancement of the ipsilateral endolymphatic sac was observed in 30 of the 40 patients with sudden hearing loss (75%). Twenty of these 30 patients also showed enhancement on the contralateral side, and 1 patient showed enhancement only on the contralateral side. Only 1 of the 5 patients with Meniere's disease showed enhancement. Nine of the 40 control subjects (22.5%) showed enhancement (bilateral enhancement in 5 subjects, unilateral in 4). The frequency of enhancement in patients with sudden hearing loss was significantly higher than that in control subjects (P<0.0001) or patients with Meniere's disease (P<0.05). The frequency of contrast enhancement of the endolymphatic sac is significantly increased in patients with sudden hearing loss, but further study is necessary to clarify the relationship between this finding and the pathophysiology of sudden hearing loss. (orig.)

Naganawa, Shinji; Koshikawa, Tokiko; Fukatsu, Hiroshi; Ishigaki, Takeo [Department of Radiology, Nagoya University School of Medicine (Japan); Nakashima, Tsutomu [Department of Otolayngology, Nagoya University School of Medicine (Japan); Ichinose, Nobuyasu [Toshiba Nasu Operations, Tochigi (Japan)

2002-05-01

191

Analogous and Distinctive Patterns of Prelinguistic Communication in Toddlers with and without Hearing Loss  

Science.gov (United States)

Purpose: This study was conducted to compare the prelinguistic communicative abilities of toddlers with hearing loss and without hearing loss during the 2nd year of life and shortly before the emergence of productive single-word lexicons. Method: The participants were 28 toddlers with hearing loss who participated in an early intervention program…

Zaidman-Zait, Anat; Dromi, Esther

2007-01-01

192

Children with Permanent Hearing Loss and Associated Disabilities: Revisiting Current Epidemiological Data and Causes of Deafness  

Science.gov (United States)

This article reviews current epidemiological studies estimating the prevalence and incidence of permanent hearing loss in children. In particular, it addresses trends in ages of onset of hearing loss and causes. Studies estimating the number of children with hearing loss and additional special needs in various countries are presented, as well as…

Picard, Michel

2004-01-01

193

Slc26a4-insufficiency causes fluctuating hearing loss and stria vascularis dysfunction.  

Science.gov (United States)

SLC26A4 mutations can cause a distinctive hearing loss phenotype with sudden drops and fluctuation in patients. Existing Slc26a4 mutant mouse lines have a profound loss of hearing and vestibular function, with severe inner ear malformations that do not model this human phenotype. In this study, we generated Slc26a4-insufficient mice by manipulation of doxycycline administration to a transgenic mouse line in which all Slc26a4 expression was under the control of doxycycline. Doxycycline was administered from conception to embryonic day 17.5, and then it was discontinued. Auditory brainstem response thresholds showed significant fluctuation of hearing loss from 1 through 3months of age. The endocochlear potential, which is required for inner ear sensory cell function, correlated with auditory brainstem response thresholds. We observed degeneration of stria vascularis intermediate cells, the cells that generate the endocochlear potential, but no other abnormalities within the cochlea. We conclude that fluctuations of hearing result from fluctuations of the endocochlear potential and stria vascularis dysfunction in Slc26a4-insufficient mouse ears. This model can now be used to test potential interventions to reduce or prevent sudden hearing loss or fluctuation in human patients. Our strategy to generate a hypomorphic mouse model utilizing the tet-on system will be applicable to other diseases in which a hypomorphic allele is needed to model the human phenotype. PMID:24561068

Ito, Taku; Li, Xiangming; Kurima, Kiyoto; Choi, Byung Yoon; Wangemann, Philine; Griffith, Andrew J

2014-06-01

194

[Longitudinal audiometric studies concerning progression of noise induced hearing loss (author's transl)].  

Science.gov (United States)

The development of occupational hearing loss is very important for the recommendation to change the work place. 1960 Dieroff has described a phasic development of noise induced hearing loss. After ten years in noisy environment no further development of hearing impairment was determinable. Recent investigations point to a logarithmical respectively linear dependence of noise induced permanent threshold shift on the duration of exposure to noise. During our observation over a period of two years of employees working on noisy jobs, no stay of noise induced permanent threshold shift proceeding could be stated after ten or twenty years. As the raiting sound level of the working places, which we have studied, had only approx. 60 to 100 dB(A), it can be assumed, that under these conditions the noise induced hearing loss developes delayed and the noise induced permanent threshold shift increases as long as it must be worked under noisy conditions. The noise induced hearing loss depends on the intensity of noise exposure of the different groups. Also the group of storehouse- and court personnel as well as the drivers, being exposed only to a raiting sound level of approx. 65-75 dB(A), showed a significant higher noise induced permanent threshold shift than the group of administrative employees. PMID:135157

Irion, H; Legler, U

1976-05-01

195

Antioxidant-enriched diet does not delay the progression of age-related hearing loss  

Science.gov (United States)

Oxidative stress has been linked to noise- and drug-induced as well as age-related hearing loss. Antioxidants can attenuate the decline of cochlear structure and function after exposure to noise or drugs, but it is debated as to whether they can protect from age-related hearing loss. In a long-term longitudinal study, 10-month old female CBA/J mice were placed on either a control or antioxidant-enriched diet and monitored through 24 months of age. Supplementation with vitamins A, C, and E, L-carnitine and ?-lipoic acid significantly increased the antioxidant capacity of inner ear tissues. However, by 24 months of age, the magnitude of hearing loss was equal in both groups. Likewise, there were no significant differences in hair cell loss or degeneration of spiral ganglion cells. We conclude that dietary manipulations can alter cochlear antioxidant capacity but do not ameliorate age-related sensorineural hearing loss in the CBA/J mouse.

Sha, Su-Hua; Kanicki, Ariane; Halsey, Karin; Wearne, Kimberly Anne; Schacht, Jochen

2011-01-01

196

Hearing loss and cochlear damage in experimental pneumococcal meningitis, with special reference to the role of neutrophil granulytes  

DEFF Research Database (Denmark)

Hearing loss is a well-known sequelae from meningitis, affecting up to 25% of survivors. However, the principal components of the infectious and inflammatory reaction responsible for the sensorineural hearing loss remain to be identified. The present study aimed to investigate the impact of an augmented neutrophil response on the development of hearing loss and cochlear damage in a model of experimental pneumococcal meningitis in rats. Hearing loss and cochlear damage were assessed by distortion product oto-acoustic emissions (DPOAE), auditory brainstem response (ABR) and histopathology in rats treated with ceftriaxone 28 h after infection. Rats were treated with Granulocyte Colony Stimulating Factor (G-CSF) initiated prior to infection, 28 h after infection or with ceftriaxone only. Rats were followed for 7 days, and assessment of hearing was performed before infection and 24 h and day 8 after infection. Pretreatment with G-CSF increased hearing loss 24 h after infection and on day 8 compared to untreated rats (Mann-Whitney, P = 0.012 and P = 0.013 respectively). The increased sensorineural hearing loss at day 8 was associated with significantly decreased spiral ganglion cell counts (P = 0.0006), increased damage to the organ of Corti (P = 0.007), increased areas of inflammatory infiltrates (P = 0.02) and increased white blood cell (WBC) counts in cerebrospinal fluid on day 8 after infection (P = 0.0084). Initiation of G-CSF 28 h after infection did not significantly affect hearing loss or cochlear pathology compared to controls. In conclusion, the inflammatory host reaction contributes significantly to the development of hearing loss in experimental meningitis.

Brandt, CT; Caye-Thomsen, P

2006-01-01

197

MR imaging of 495 consecutive cases with sensorineural hearing loss  

International Nuclear Information System (INIS)

495 consecutive patients with SNHL and 120 age-matched healthy controls were examined. Spin-echo (SE) and fast spin-echo (FSE) images were used with 1.5 T equipment. An intracranial abnormality was found in 211 (42.6%) of the patients with 95 (19.2%) along the acoustic pathway. Eleven of the 95 patients had sensory hearing loss while 84 had neural hearing loss with the retrocochlear auditory pathway affected by lesions. In 62 of the 84 patients, the internal acoustic canal and cerebellopontine angle were involved. Twenty-two patients had intra-axial lesions. The controls had no pathologic changes along the auditory pathway. (orig./UG)

1995-11-01

198

MR imaging of 495 consecutive cases with sensorineural hearing loss  

Energy Technology Data Exchange (ETDEWEB)

495 consecutive patients with SNHL and 120 age-matched healthy controls were examined. Spin-echo (SE) and fast spin-echo (FSE) images were used with 1.5 T equipment. An intracranial abnormality was found in 211 (42.6%) of the patients with 95 (19.2%) along the acoustic pathway. Eleven of the 95 patients had sensory hearing loss while 84 had neural hearing loss with the retrocochlear auditory pathway affected by lesions. In 62 of the 84 patients, the internal acoustic canal and cerebellopontine angle were involved. Twenty-two patients had intra-axial lesions. The controls had no pathologic changes along the auditory pathway. (orig./UG).

Wu, W. [Univ. Hospital, Linkoeping (Sweden). Dept. of Diagnostic Radiology]|[China-Japan Friendship Hospital, Beijing (China); Thuomas, K.AA. [Univ. Hospital, Linkoeping (Sweden). Dept. of Diagnostic Radiology

1995-11-01

199

Cisplatin and Aminoglycoside Antibiotics: Hearing Loss and Its Prevention  

Science.gov (United States)

This review introduces the pathology of aminoglycoside antibiotic and the cisplatin chemotherapy classes of drugs, discusses oxidative stress in the inner ear as a primary trigger for cell damage, and delineates the ensuing cell death pathways. Among potentially ototoxic (damaging the inner ear) therapeutics, the platinum-based anti-cancer drugs and the aminoglycoside antibiotics are of critical clinical importance. Both drugs cause sensorineural hearing loss in patients, a side effect that can be reproduced in experimental animals. Hearing loss is reflected primarily in damage to outer hair cells, beginning in the basal turn of the cochlea. In addition, aminoglycosides might affect the vestibular system while cisplatin seems to have a much lower likelihood to do so. Finally, based on an understanding the mechanisms of ototoxicity pharmaceutical ways of protection of the cochlea are presented

Schacht, Jochen; Talaska, Andra E.; Rybak, Leonard P.

2013-01-01

200

The mitochondrion: a perpetrator of acquired hearing loss.  

Science.gov (United States)

Age, drugs, and noise are major causes of acquired hearing loss. The involvement of reactive oxygen species (ROS) in hair cell death has long been discussed, but there is considerably less information available as to the mechanisms underlying ROS formation. Most cellular ROS arise in mitochondria and this review will evaluate evidence for mitochondrial pathology in general and dysfunction of the mitochondrial respiratory chain in particular in acquired hearing loss. We will discuss evidence that different pathways can lead to the generation of ROS and that oxidative stress might not necessarily be causal to all three pathologies. Finally, we will detail recent advances in exploiting knowledge of aminoglycoside-mitochondria interactions for the development of non-ototoxic antibacterials. This article is part of a Special Issue entitled "Annual Reviews 2013". PMID:23361190

Böttger, Erik C; Schacht, Jochen

2013-09-01

 
 
 
 
201

Posterior fossa arachnoid cyst presenting with isolated sensorineural hearing loss.  

Science.gov (United States)

Arachnoid cysts are benign cysts occurring in the intra-arachnoid space and containing cerebrospinal fluid. They constitute approximately 1 per cent of all intracranial masses. They are uncommon in the posterior cranial fossa. Common presenting symptoms include headaches, seizures, focal neurologic signs and vague dizziness. Magnetic resonance imaging is the preferred method of investigation, and the treatment for symptomatic cysts is generally surgical drainage. We report the unusual presentation of a young patient with a posterior fossa arachnoid cyst that manifested in the form of isolated unilateral sensorineural hearing loss. The patient underwent posterior fossa craniotomy and marsupialization of the cyst. To our knowledge, posterior fossa arachnoid cyst presenting with isolated hearing loss alone has not been reported in the English literature. A review of the literature pertaining to posterior fossa arachnoid cysts, including the clinical features, diagnosis and management, is also presented. PMID:16848918

Thinakara-Rajan, T; Janjua, A; Srinivasan, V

2006-11-01

202

[Sarcoidosis presenting with recurrent aseptic meningitis and acute hearing loss].  

Science.gov (United States)

Neurologic complications occur in 5% of patients with sarcoidosis. Neurosarcoidosis ranges from mild neurologic deficits to a destructive, life-threatening disease, and at times is the only presenting symptom of sarcoidosis, thus posing a diagnostic challenge for the doctor neurologic symptoms include cranial nerve palsies, with the vestibulocochlear nerve rarely being involved. We present a patient with neurosarcoidosis manifesting as recurrent episodes of aseptic meningitis, vertigo, and acute hearing loss. PMID:22844729

Nitzan, Orna; Elias, Mazen; Saliba, Walid

2012-05-01

203

The Prevention of Noise Induced Hearing Loss in Children  

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Increasingly, our acoustic environment is filled with amplified sound sources (e.g., MP3 players, video game stations, and sports/entertainment venues). There is serious concern and also some controversy about the risks of acoustic trauma in children. This overview provides some basic information on the physiological mechanisms that lead to noise induced hearing loss, a survey of various studies that, on balance, indicates that there is cause for concern, and finally a discussion on measures ...

Harrison, Robert V.

2012-01-01

204

Genetic hearing loss with preauricular sinus and branchiogenic fistula.  

Science.gov (United States)

A mother and her two children had hearing loss associated with bilateral preauricular sinus and branchiogenic fistula. All six cochleas studied showed two turns rather than 2 1/2 turns. Complete studies including audiometry, tympanotomy findings, and temporal bone polytomography of these anomalies are reported. Similar cases reported in the English literature are reviewed. It seems that all previous cases may have had an abnormal cochlea as was seen in these cases. PMID:921599

Won, K H; Gayler, B W; Shimizu, H

1977-11-01

205

Increasing Communication in Children With Concurrent Vision and Hearing Loss  

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Nine children with complex communication needs and concurrent vision and hearing losses participated in an intervention program aimed at increasing intentional prelinguistic communication. The intervention constituted a pilot, descriptive study of an adapted version of prelinguistic milieu teaching, hence referred to as A-PMT. In A-PMT, natural gestures and vocalizations were targeted in child-focused, one-on-one activities conducted by a member of the project staff. Adaptations included usin...

Brady, Nancy C.; Bashinski, Susan M.

2008-01-01

206

Bilateral otitis media and hearing loss in an adult.  

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Bilateral otitis media, an uncommon entity in adults, may represent the initial manifestation of a life-threatening systemic disease. Prompt recognition and treatment of the underlying disease is needed to preserve auditory function and prevent involvement of other organ systems. We present the case of a thirty-four-year-old male with bilateral serous otitis media and progressive hearing loss, which was refractory to antimicrobial therapy and middle ear drainage. A mastoid biopsy revealed nec...

Colodny, S. M.; Heinemann, F. S.; Mellors, J. W.

1986-01-01

207

Brain-stem auditory evoked responses during microvascular decompression for trigeminal neuralgia: Predicting post-operative hearing loss  

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Full Text Available Context: The importance of brainstem auditory evoked potential monitoring in reducing hearing loss during microvascular decompression for trigeminal neuralgia is now accepted. However the extent of the changes in the pattern of these potentials and the safe limits to which these changes are relevant in reducing postoperative hearing loss have not been established. Aims: The aim of this study is to quantify these changes and relate these to the postoperative hearing loss. Settings and Design: This study was done at the Walton Centre for neurology and neurosurgery, Liverpool, United Kingdom. The study was designed to give a measure of the change in the wave pattern following microvascular decompression and relate it to postoperative hearing loss. Materials and Methods: Seventy-five patients undergoing microvascular decompression for trigeminal neuralgia had preoperative and postoperative hearing assessments and intraoperative brainstem auditory evoked potential monitoring. Statistical Analysis Used: Chi-square tests. Results: It was found that the wave V latency was increased by more than 0.9ms in nine patients, eight of whom suffered significant postoperative hearing loss as demonstrated by audiometry. It was also seen that progressive decrease in amplitude of wave V showed progressive hearing loss with 25% loss when amplitude fell by 50 and 100% loss when wave V was lost completely. However most of the patients did not have a clinically manifest hearing loss. Conclusions: A per-operative increase in the latency of wave V greater than 0.9 ms and a fall of amplitude of wave V of more than 50% indicates a risk to hearing.

Ramnarayan Ramachandran

2006-01-01

208

Evaluation of hearing loss in tympanic membrane perforation.  

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To evaluate and analyse the hearing loss in tympanic membrane perforation based on size, site and duration of perforation. The material for this study was comprised of 100 patients of either sex and of age 15 years and above selected randomly. Size of tympanic membrane perforation was assessed under microscope using calibrated wire look. Patients were divided into three groups according to size; group I (0-9 mm(2)), Group II (9-30 mm(2)), Group III (? 30 mm(2)); according to site into anterior and posterior group; according to involvement of malleus into malleolar and non malleolar and according to duration into Group A ( 0.05). Hearing loss was more in malleolar perforation (t - 5.74, p < 0.001). Hearing loss increased as the duration of disease increased [A vs. B (t - 2.01, p < 0.043), A vs. C (t - 5.49, p < 0.001), B vs. C (t - 4.14, p < 0.001)]. PMID:22754796

Pannu, Kulwant Kaur; Chadha, Snya; Kumar, Dinesh; Preeti

2011-07-01

209

Comparação entre critérios de recuperação auditiva na perda neurossensorial súbita / Comparison of hearing recovery criteria in sudden sensorineural hearing loss  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese Inúmeros métodos de análise da recuperação auditiva na perda auditiva neurossensorial súbita idiopática (PANSI) dificultam a comparação adequada dos diversos tratamentos encontrados na Literatura. OBJETIVO: Comparar diversos critérios de recuperação auditiva na PANSI, baseados na Literatura. MATERIA [...] L E MÉTODO: Foi realizado um estudo clínico observacional de coorte, a partir de um protocolo prospectivo, em pacientes com PANSI, atendidos entre 2000 e 2010. Foram comparados cinco critérios de recuperação auditiva significativa e quatro critérios para recuperação completa, pela audiometria tonal, por meio de teste não paramétrico e de comparações múltiplas, ambos com um nível de significância de 5%. Após determinação do critério de recuperação auditiva mais rígido, foram adicionados parâmetros da audiometria vocal. RESULTADOS: Houve diferença significativa, entre esses critérios (p Abstract in english The countless methods available to analyze hearing recovery in idiopathic sudden sensorineural hearing loss (ISSHL) cases hinder the comparison of the various treatments found in the literature. OBJECTIVE: This paper aims to compare the different criteria for hearing recovery in ISSHL found in the l [...] iterature. MATERIALS AND METHODS: This is an observational clinical cohort study from a prospective protocol in patients with ISSHL, treated between 2000 and 2010. Five criteria were considered for significant hearing recovery and four for complete recovery by pure tone audiometry, using non-parametric tests and multiple comparisons at a significance level of 5%. After determining the stricter criteria for hearing recovery, vocal audiometry parameters were added. RESULTS: There was a significant difference between the criteria (p

Daniel Paganini, Inoue; Eduardo Amaro, Bogaz; Flávia, Barros; Norma de Oliveira, Penido.

210

Molecular and hereditary mechanisms of sensorineural hearing loss with focus on selected endocrinopathies.  

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Hearing loss is one of the most widespread sensory disorders. The incidence of deafness in general population is 1:1000 newborns. About one half of the cases of the congenital sensorineural hearing loss (SNHL) is inherited. Recessive mutations in the gap junction beta 2 (GJB2) gene are the most common genetic causes of the nonsyndromic SNHL. The GJB2 encodes a protein connexin 26 which forms a subunit of gap junction essential for the correct function of the inner ear. The syndromic SNHL is associated with a wide range of other symptoms, which encompass also dysfunctions of endocrine organs. The Pendred syndrome associated with the hearing impairment is characterized by a prelingual, bilateral sever to profound SNHL, goiter, and iodine organification defect. It is an autosomal recessive disorder, which develops due to mutations in pendrin, an anion channel encoded by SLC26A4 gene. Another important type of syndromic hearing loss is the Maternally Inherited Diabetes and Deafness syndrome, which is caused by several mitochondrial DNA mutations. These mutations are clinically manifested by a hearing impairment with development of the diabetes in the adult age. Hearing impairment occurs during puberty when sensation of high frequency tones is affected following with further progress to profound bilateral sensorineural hearing impairment in the whole frequency range. This review deals with the molecular mechanisms of common genetic causes of the hereditary SNHL along with the selected endocrinopathies emphasizing that the DNA analyses along with the functional studies significantly contribute to the early SNHL diagnosis followed by personalized therapy and genetic counseling. PMID:22808909

Masindova, I; Varga, L; Stanik, J; Valentinova, L; Profant, M; Klimes, I; Gasperikova, D

2012-07-01

211

[Intelligibility of monosyllables in relation to tone hearing in noise-induced hearing loss].  

Science.gov (United States)

We found a method based on analysis of the pattern of recognition (discrimination) to predict the intelligibility of monosyllables in the speech audiogram from the hearing loss values of the tone audiogram. A pattern of recognition (discrimination) function is required for every monosyllable at every intensity level of the test. The great number of functions (8 X 200) (i.e. 1600 functions) involved requires the accommodation capacity of a computer installed at the place of work. PMID:3626717

Tymnik, G; Stange, E; Lessing, G; Zobelt, U

1987-06-01

212

Temporal Intraspeech Masking of Plosive Bursts: Effects of Hearing Loss and Frequency Shaping  

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Purpose: The purposes were (a) to compare masking of consonant bursts by adjacent vowels for listeners with and without hearing loss and (b) to determine the extent to which the temporal intraspeech masking can be reduced by a simulated hearing-aid frequency-response shaping. Method: Fourteen adults with sensorineural hearing loss and 10 with…

Mackersie, Carol L.

2007-01-01

213

Auditory Temporal-Organization Abilities in School-Age Children with Peripheral Hearing Loss  

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Purpose: The objective was to assess auditory sequential organization (ASO) ability in children with and without hearing loss. Method: Forty children 9 to 12 years old participated in the study: 12 with sensory hearing loss (HL), 12 with central auditory processing disorder (CAPD), and 16 with normal hearing. They performed an ASO task in which…

Koravand, Amineh; Jutras, Benoit

2013-01-01

214

Current aspects of hearing loss from occupational and leisure noise  

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Full Text Available Hearing loss from occupational and leisure noise numbers amongst the most frequent causes of an acquired sensorineural hearing loss. Here we present a review of up-to-date findings on the pathophysiology of acoustic injury to the inner ear, with special attention being paid to its molecular-biological and genetic aspects. Epidemiological aspects shall also be dealt with, as shall the roles of lacking recovery from occupational noise due to additional exposure by leisure noise and the combined exposure of noise and chemicals. Based on the epidemiological and pathophysiological findings and against the background of published animal-experimental, pre-clinical and clinical findings, the various approaches for prevention, protection and therapeutic intervention with acoustic trauma are discussed. Pharmacological strategies involving anti-oxidative, anti-excitotoxic and anti-apoptotic substances as well as non-pharmacological strategies like "sound conditioning" are given attention. Furthermore, systemic and local substance application as well as the therapy of acute acoustic trauma and chronic hearing problems (including modern therapy forms for comorbidities such as tinnitus shall be delved into.

Plontke, S.

2004-12-01

215

Some Non-Occupational Aspects of Sensorineural Loss of Hearing Acuity - A Proposed Design for Study.  

Science.gov (United States)

Although the adverse effects of occupationally associated noise on hearing have been well documented, review of the recent literature revealed few studies which have carefully measured the role of non-occupational loud sound in sensorineural hearing loss....

T. Varley

1985-01-01

216

[Frequency-dependent cochlear microphonics in inner ear hearing loss with various pitch thresholds].  

Science.gov (United States)

Promontory recordings of the cochlear microphonics (CM) after stimulation with 0.5, 1 and 2 kHz tone bursts at 120 dB SPL were performed on normal subjects and patients with various, levels of sensory hearing loss. A significant correlation was found between frequency-related CM amplitudes and the configuration of the pure-tone audiogram. Such recordings provide objective information on hearing abilities at low and middle frequencies and are thus a relevant tool in clinical audiometry. PMID:2917880

Marangos, N; Hesse, G; Mausolf, A

1989-01-01

217

Effects of cigarette smoking on the evolution of hearing loss caused by industrial noise  

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Full Text Available The few studies evaluating the changes caused by cigarette smoking on hearing loss induced by occupational exposure to noise have reached discordant conclusions. The aim of this study is to investigate the interactions between cigarette smoking and occupational exposure to noise as risk factors in the onset and development of hearing loss. The study was performed on a sample of 557 shipyard workers exposed to noise at an Equivalent Level (Leq of 93 dBA. On the basis of their smoking habits, they were divided into three groups: group (A, non-smokers; group (B, smokers (15-30 cigarettes per day; and group (C, heavy smokers (over 30 cigarettes per day. The study focussed on the audiometric responses of the subjects at the frequencies of 500, 1000, 2000, 3000 and 4000 Hz. The results were then compared using statistical techniquees (Internal correlation coefficient, exponential model, ANCOVA, NPC test. Comparison of the audiometric responses showed statistically significant differences between the three groups. Non-parametric analysis, performed using the NPC test, highlighted that the interaction between smoking and exposure to noise has an influence on hearing loss at all frequencies, and particularly at high frequencies (3000-4000 Hz. The data obtained from the examined sample show that smoking and exposure to noise cause an increase in occupational hearing loss and that this is directly related to the number of cigarettes smoked.

Abbate Carmelo

2010-10-01

218

Cumulative Lead Exposure and Age-related Hearing Loss: The VA Normative Aging Study  

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Although lead has been associated with hearing loss in occupational settings and in children, little epidemiologic research has been conducted on the impact of cumulative lead exposure on age-related hearing loss in the general population. We determined whether bone lead levels, a marker of cumulative lead exposure, are associated with decreased hearing ability in 448 men from the Normative Aging Study, seen between 1962 and 1996 (2,264 total observations). Air conduction hearing thresholds w...

Park, Sung Kyun; Elmarsafawy, Sahar; Mukherjee, Bhramar; Spiro, Avron; Vokonas, Pantel S.; Nie, Huiling; Weisskopf, Marc G.; Schwartz, Joel; Hu, Howard

2010-01-01

219

Prevalence of Hearing Loss in Newborns Admitted to Neonatal Intensive Care Unit  

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Introduction: Hearing is essential for humans to communicate with one another. Early diagnosis of hearing loss and intervention in neonates and infants can reduce developmental problems. The aim of the present study was to assess the prevalence of hearing impairment in newborns admitted to a neonatal intensive care unit (NICU) and analyze the associated risk factors.   Materials and Methods: This cross-sectional study was conducted to assess the prevalence of hearing loss in neonates who wer...

2012-01-01

220

Infants and Children with Hearing Loss Need Early Language Access  

Science.gov (United States)

Around 96 percent of children with hearing loss are born to parents with intact hearing,1 who may initially know little about deafness or sign language. Therefore, such parents will need information and support in making decisions about the medical, linguistic, and educational management of their child. Some of these decisions are time-sensitive and irreversible and come at a moment of emotional turmoil and vulnerability (when some parents grieve the toss of a normally hearing child).2 Clinical research indicates that a deaf child’s poor communication skills can be made worse by increased level of parental depression.3 Given this, the importance of reliable and up-to-date support for parents’ decisions is critical to the overall well-being of their child.4 In raising and educating a child, parents are often offered an exclusive choice between an oral environment (including assistive technology, speech reading, and voicing) and a signing environment. A heated controversy surrounds this choice, and has since at least the late 19th century, beginning with the International Congress on the Education of the Deaf in Milan, held in 1880.5 While families seek advice from many sources, including, increasingly, the internet,6 the primary care physician (PCP) is the professional medical figure the family interacts with repeatedly.7 The present article aims to help family advisors, particularly the PCP and other medical advisors in this regard. We argue that deaf children need to be exposed regularly and frequently to good language models in both visual and auditory modalities from the time hearing loss is detected and continued throughout their education to ensure proper cognitive, psychological, and educational development. Since there is, unfortunately, a dearth of empirical studies on many of the issues families must confront, professional opinions, backed by what studies do exist, are the only option. We here give our strongly held professional opinions and stress the need for improved research studies in these areas.

Kushalnagar, Poorna; Mathur, Gaurav; Moreland, Christopher J.; Napoli, Donna Jo; Osterling, Wendy; Padden, Carol; Rathmann, Christian

2010-01-01

 
 
 
 
221

GRM7 variants associated with age-related hearing loss based on auditory perception.  

Science.gov (United States)

Age-related hearing impairment (ARHI), or presbycusis, is a common condition of the elderly that results in significant communication difficulties in daily life. Clinically, it has been defined as a progressive loss of sensitivity to sound, starting at the high frequencies, inability to understand speech, lengthening of the minimum discernable temporal gap in sounds, and a decrease in the ability to filter out background noise. The causes of presbycusis are likely a combination of environmental and genetic factors. Previous research into the genetics of presbycusis has focused solely on hearing as measured by pure-tone thresholds. A few loci have been identified, based on a best ear pure-tone average phenotype, as having a likely role in susceptibility to this type of hearing loss; and GRM7 is the only gene that has achieved genome-wide significance. We examined the association of GRM7 variants identified from the previous study, which used an European cohort with Z-scores based on pure-tone thresholds, in a European-American population from Rochester, NY (N = 687), and used novel phenotypes of presbycusis. In the present study mixed modeling analyses were used to explore the relationship of GRM7 haplotype and SNP genotypes with various measures of auditory perception. Here we show that GRM7 alleles are associated primarily with peripheral measures of hearing loss, and particularly with speech detection in older adults. PMID:23102807

Newman, Dina L; Fisher, Laurel M; Ohmen, Jeffrey; Parody, Robert; Fong, Chin-To; Frisina, Susan T; Mapes, Frances; Eddins, David A; Robert Frisina, D; Frisina, Robert D; Friedman, Rick A

2012-12-01

222

The need for improved detection and management of adult-onset hearing loss in australia.  

Science.gov (United States)

Adult-onset hearing loss is insidious and typically diagnosed and managed several years after onset. Often, this is after the loss having led to multiple negative consequences including effects on employment, depressive symptoms, and increased risk of mortality. In contrast, the use of hearing aids is associated with reduced depression, longer life expectancy, and retention in the workplace. Despite this, several studies indicate high levels of unmet need for hearing health services in older adults and poor use of prescribed hearing aids, often leading to their abandonment. In Australia, the largest component of financial cost of hearing loss (excluding the loss of well-being) is due to lost workplace productivity. Nonetheless, the Australian public health system does not have an effective and sustainable hearing screening strategy to tackle the problem of poor detection of adult-onset hearing loss. Given the increasing prevalence and disease burden of hearing impairment in adults, two key areas are not adequately met in the Australian healthcare system: (1) early identification of persons with chronic hearing impairment; (2) appropriate and targeted referral of these patients to hearing health service providers. This paper reviews the current literature, including population-based data from the Blue Mountains Hearing Study, and suggests different models for early detection of adult-onset hearing loss. PMID:23710184

McMahon, Catherine M; Gopinath, Bamini; Schneider, Julie; Reath, Jennifer; Hickson, Louise; Leeder, Stephen R; Mitchell, Paul; Cowan, Robert

2013-01-01

223

The Effect of Stimulus Bandwidth on Perception of Fricative /s/ among Individuals with Different Degrees of Sensorineural Hearing Loss  

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Full Text Available Most of the speech sounds that contribute to speech intelligibility are dominated by high-frequency components. The phoneme /s/ is the third or fourth most frequently occurring phoneme in the English language and second most frequently occurring consonantal phoneme in Hindi language. Given the importance of the phoneme /s/, it is ironic that, this sound contains the highest frequency acoustic elements of any speech sound in English and most of the non-English languages ranging from 4500 Hz to more than 8000 Hz. The most common type of hearing impairment affecting speech perception is high-frequency sensorineural loss (SN and such individuals require good high frequency audibility in order to better perceive fricative cues, regardless of hearing status. While many studies appear to support the general notion that high-frequency amplification may not always be beneficial, the inter-subject variability in most studies precludes a clearly defined rule that would distinguish listeners who are likely to benefit from high-frequency amplification from those who are not. The current study is aimed to determine and compare the effective bandwidth required for the perception of fricative /s/ in individuals with normal hearing and hearing impairment as a function of degree of hearing loss. A total of 100 Hindi speaking subjects equally divided into four groups (Group I: Normal hearing, Group II: Moderate SN hearing loss, Group III: Moderately severe SN hearing loss, Group IV: Severe SN hearing loss participated in the study. Nonsense syllables containing the phonemes /s/, /f/, /?/ and /c/ in /i/ vowel context and low pass filtered at 1, 2, 3, 4, 5, 6, 7, 8 and 9 KHz produced by a female talker were used as stimulus. The results revealed that there was a statistically significant effect (p0.05 was seen at 9 KHz between groups. In addition, individuals with normal hearing required lower bandwidth for accurate fricative perception and there was a statistically significant difference (p<0.05 in mean bandwidth between groups. Among the hearing impaired group, as the degree of hearing loss increased the subjects required higher bandwidth for accurate perception of fricative. This study has important implications in knowing the effective bandwidth required for the perception of high frequency speech sounds among individuals with hearing loss on individual basis which in turn helps in the selection of appropriate rehabilitative devices.

V. Josephine Vinila

2011-12-01

224

SENSORY HEARING LOSS IN CHILDREN WITH MUMPS INFECTION  

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Full Text Available Objective:Mumps infection is endemic in Iran and mumps parotiditis is acommon disease in Iranian children. There has been a dramaticdecrease in the worldwide incidence of mumps since the introductionand use in 1968 of the very effective and inexpensive mumps vaccine.In Iran probably due to a higher percentage of unvaccinated youngpersons <15yr, the incidence rate of mumps infection and its sequelaare higher in comparison to corresponding data from developedcountries prior to comprehensive vaccination programs. The aim ofthe study was to investigate the effects of the mumps virus on cochlearfunction and to determine the frequency of related Sensory NeuralHearing Loss (SNHL in children.Material& Methods:This descriptive case-series study was conducted in 94children, agedless than 14 years, hospitalized between 1999 and 2001, in thepediatric ward of the Hazrat Rasool Hospital in Tehran. All patientswith documented mumps infection (specific mumps-IgM antibodywere evaluated twice for audiometeric function on the basis ofdiagnostic parameters for sensory neural hearing loss; the first evaluationwas done on admission and the second three weeks later. 54 patients(age range 1-14y, mean age 4.83±3.93, male: female ratio30:24were studied in two years.Results:The highest incidence of mumps was seen in winter (37% and spring(28% and the lowest in summer (13%. Specific IgM antibody formumps virus was detected in 74 children. Comprehensive audiologicevaluation was done in 54 patients at admission and again 3 weekslater. SNHL was detected in 7.2% of patients; the 4.4% incidence ofSNHL in this study was higher than in other studies in developedcountries prior to comprehensive vaccination programs.Conclusion:Implementation of comprehensive vaccination programs in youngIranians could dramatically reduce the burden and costs imposed bythe infection and its sequelae.Keywords: Mumps infection ;SNLH(sensorineural hearing loss;Mumpsvaccination

S. Noorbaksh

2006-10-01

225

Can Noise in Dental Clinic Produce Hearing Loss?  

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Full Text Available Introduction: The sensorial hearing loss and irreversible noise induced is the major evitable occupational cause of hearing loss worldwide. The dentists are health professionals exposed to noises from equipment in their clinics and may suffer hearing losses. Objective: Measure the noise intensities emitted by the high rotation motors (mar used in public and private dental clinics, check whether they are harmful for the human ear and compare the results obtained in such services. Method: Serial, retrospective study with measures of the noise intensities in dBNA with a decibelimeter Minipa MSL-1352C, USA, in four dental clinics of the public service and four private clinics in Jundiaí-SP, initially from the basal environment noise in each clinic, during five minutes and then from the noise emitted by the high rotation motor (mar in operation during five minutes to obtain the averages. Results:Public clinics: 1basal medium=56.4dB;mar=77.2dB. 2basal medium=61.7dB;mar=73.7dB. 3basal medium=61.07dB;mar=75.04dB. 4basal medium=63.6dB;mar=77.3dB. Private clinics: 1basal medium=60,7dB;mar=79,1dB. 2basal=60,7dB;mar=83,1dB. 3basal=58,4dB;mar=75,5dB. 4basal=63dB;mar=76dB. Conclusion: The intensities measured of noise emitted by high rotation motors used in public and private dental clinics are below the limits harmful to the auditory health. In the public service, the basal medium noise intensity is higher than that of the private clinics, however the one of the high rotation motors is higher in the private clinics.

Lourenço, Edmir Américo

2011-01-01

226

Mechanisms of Hearing Loss after Blast Injury to the Ear  

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Given the frequent use of improvised explosive devices (IEDs) around the world, the study of traumatic blast injuries is of increasing interest. The ear is the most common organ affected by blast injury because it is the body’s most sensitive pressure transducer. We fabricated a blast chamber to re-create blast profiles similar to that of IEDs and used it to develop a reproducible mouse model to study blast-induced hearing loss. The tympanic membrane was perforated in all mice after blast e...

Cho, Sung-il; Gao, Simon S.; Xia, Anping; Wang, Rosalie; Salles, Felipe T.; Raphael, Patrick D.; Abaya, Homer; Wachtel, Jacqueline; Baek, Jongmin; Jacobs, David; Rasband, Matthew N.; Oghalai, John S.

2013-01-01

227

Frequency of Sensory Neural Hearing Loss in Major Beta-Thalassemias in Southern Iran  

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Full Text Available Objective:The thalassemias are among the most common genetic disorders worldwide, occurring more frequently in the Mediterranean region. The aim of this study was to determined frequency of sensory-neural hearing loss in major ß- thalassemias transfusion dependent patients in south of Iran. Methods:A cross sectional study on 308 cases of major beta-thalassemia patients referring to Thalassemia Center of Shiraz University of Medical Sciences between 2006-2007 years. The diagnosis of ß- thalassemia major was based on clinical history, complete blood count and hemoglobine electrophoresis. Clinical data such as serum ferritin level, deferoxamine (DFO dose, mean daily doses of DFO (mg/kg and audiometric variables was recorded. Findings:Out of 308 cases, 283 (96.5% had normal hearing and 10 (3.5% sensorineural hearing loss. There was no statically significant difference between two groups regarding mean age, weight, age at the first blood transfusion, age at the first DFO infusion. Conclusion:We found the lowest incidence of sensorineural hearing loss in a large population of patients suffered from major thalassemia who received DFO. We show that DFO is not ototoxic at a low dose. When considering all related literature, as a whole there has been much critical misrepresentation about DFO ototoxicity.

Seyed-Taghi Heydari

2010-09-01

228

Frequency of Sensory Neural Hearing Loss in Major Beta-Thalassemias in Southern Iran  

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Full Text Available Objective:The thalassemias are among the most common genetic disorders worldwide, occurring more frequently in the Mediterranean region. The aim of this study was to determined frequency of sensory-neural hearing loss in major ß- thalassemias transfusion dependent patients in south of Iran.Methods:A cross sectional study on 308 cases of major beta-thalassemia patients referring to Thalassemia Center of Shiraz University of Medical Sciences between 2006-2007 years. The diagnosis of ß- thalassemia major was based on clinical history, complete blood count and hemoglobine electrophoresis. Clinical data such as serum ferritin level, deferoxamine (DFO dose, mean daily doses of DFO (mg/kg and audiometric variables was recorded.Findings:Out of 308 cases, 283 (96.5% had normal hearing and 10 (3.5% sensorineural hearing loss. There was no statically significant difference between two groups regarding mean age, weight, age at the first blood transfusion, age at the first DFO infusion.Conclusion:We found the lowest incidence of sensorineural hearing loss in a large population of patients suffered from major thalassemia who received DFO. We show that DFO is not ototoxic at a low dose. When considering all related literature, as a whole there has been much critical misrepresentation about DFO ototoxicity.

Abolhassan Faramarzi

2010-09-01

229

Anosmia associated with hearing loss and benign positional vertigo after head trauma  

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It is well known that head trauma may cause hearing loss, which can be either conductive or sensorineural. Benign paroxysmal positional vertigo and olfactory dysfunction due to head trauma are also well known. The association between sensorineural hearing loss and anosmia, following head trauma, is extremely rare. Two rare cases of post-traumatic occurrence of hearing loss, olfactory dysfunction and benign positional vertigo are reported and the pathophysiology of the association between sens...

Ottaviano, G.; Marioni, G.; Marchese-ragona, R.; Trevisan, Cp; Filippis, C.; Staffieri, A.

2009-01-01

230

Osteogenesis imperfecta and hearing loss--description of three case reports.  

Science.gov (United States)

Osteogenesis imperfecta is the commonest connective tissue hereditary disease. Its clinical presentation has a wide spectrum of characteristics, which includes skeletal deformities and hearing loss. We describe three case reports of individuals carriers of this disease presenting with different patterns of hearing loss. Hearing loss prevalence and patterns are variable and have no clear relation with genotype. Its assessment at initial evaluation and posterior monitoring is essential to provide the best therapeutic alternatives. PMID:24139453

Pereira da Silva, Ana; Feliciano, Telma; Figueirinhas, Rosário; Almeida E Sousa, Cecília

2013-01-01

231

Coarticulation in Early Vocalizations by Children with Hearing Loss: A Locus Perspective  

Science.gov (United States)

Locus equations derived from productions by three children with hearing loss revealed sensory and motor influences on anticipatory coarticulation. Participants who received auditory access to speech via hearing aids and cochlear implants at different ages (5-39 months) were recorded at approximately 6 and 12 months after hearing technology…

Morrison, Helen Mccaffrey

2012-01-01

232

[Usefulness of impedance audiometry in the objective evaluation of occupational hearing loss].  

Science.gov (United States)

243 workers occupationally exposed to noise have been examined by pure tone audiometry and impedance audiometry. Hearing disturbance have been diagnosed in 145 cases (62%). Impedance audiometry was performed in 74 subjects. In 47 cases (70%) hearing thresholds were found consistent in both methods whereas the other 21 cases (30%) showed different hearing thresholds. Thirteen individuals of that group exhibited hearing impairment in the cochlea. Hearing loss has been simulated in two cases. The Lüscher-Zawis?ocki test revealed 1-1.5 dB in all cases. Objective verification of loudness recruitment phenomenon allowed to state cochlear hearing localization in 31 cases. PMID:6664299

Szmeja, Z; Pruszewicz, A; Obrebowski, A; Szyfter, W

1983-01-01

233

Sudden Hearing Loss Associated with High Levels of Calcineurin Inhibitors after Liver Transplantation  

Directory of Open Access Journals (Sweden)

Full Text Available Hearing impairment in patients after liver transplantation (OLT has only been reported sporadically. However, potential ototoxic side effects may be related to immunsuppression. We report a series of 5 patients who developed sudden hearing loss after OLT and presented high levels of calcineurin inhibitors at the same time. In 4/5 patients, sudden hearing loss was bilateral. Patients` main characteristic were very heterogenous (e.g. age, time since OLT, underlying liver disease. Sudden hearing loss occured under high levels of tacrolimus (n=3, mean serum levels at the time of hearing loss: 24 ng/ml and cyclosporine A (n=2, 343 ng/ml, respectively. Further immunosuppression consisted of prednisolone (n=4 and azathioprine (n=1. There were no other risk factors such as administration of ototoxic drugs. Levels of immunsuppressants were rapidly corrected after the event. Nevertheless, in 4/5 patients hearing aids (3/4 bilateral became necessary during follow-up. Furthermore, two patients suffer from tinnitus since the hearing loss. In conclusion, high levels of calcineurin-inhibitors after OLT seem to be a risk factor for sudden hearing loss. In most cases, hearing loss was irreversible and resulted in need of a hearing aid. Neurotoxicity may be a probable mechanism. Further evaluations are necessary to allow a better understanding of the problem.

Ch. P. Strassburg

2006-03-01

234

Risk Factors for Hearing Loss in Patients Treated With Intensity-Modulated Radiotherapy for Head-and-Neck Tumors  

International Nuclear Information System (INIS)

Purpose: Radiotherapy (RT) is a common treatment of head-and-neck carcinoma. The objective of this study was to perform a prospective multivariate assessment of the dose-effect relationship between intensity-modulated RT and hearing loss. Methods and Materials: Pure tone audiometry at 0.250-16 kHz was obtained before and after treatment in 101 patients (202 ears). All patients received full-course intensity-modulated RT (range, 56-70 Gy), with a median cochlear dose of 11.4 Gy (range, 0.2-69.7). Results: Audiometry was performed 1 week before and a median of 9 weeks (range, 1-112) after treatment. The mean hearing deterioration at pure tone average air-conduction 1-2-4 kHz was small (from 28.6 dB HL to 30.1 dB HL). However, individual patients showed clinically significant hearing loss, with 10-dB threshold shift incidences of 13% and 18% at pure tone averages air-conduction 1-2-4 kHz and 8-10-12.5 kHz, respectively. Post-treatment hearing capability was unfavorable in the case of greater inner ear radiation doses (p <0.0001), unfavorable baseline hearing capability (p <0.0001), green-eyed patients (p <0.0001), and older age (p <0.0001). Using multivariate analysis, a prediction of individual hearing capabiltity after treatment was made. Conclusion: RT-induced hearing loss in the mean population is modest. However, clinically significant hearing loss was observed in older patients with green eyes and unfavorable pretreatment hearing. In these patients, the intended radiation dose may be adjusted according to the proposed predictive model, aiming to decrease the risk of ototoxicity.

2009-06-01

235

Sensori-neural hearing loss in patients treated with irradiation for nasopharyngeal carcinoma  

DEFF Research Database (Denmark)

The present investigation has been carried out to evaluate the sensitivity of the inner ear to irradiation. Cochlear function was tested in a cohort of 22 patients before and 7-84 months after receiving external irradiation for nasopharyngeal carcinoma. The pre-irradiation sensori-neural hearing threshold at 500, 1000, 2000, and 4000 Hz was used as a baseline for the individual patient, and the observed sensori-neural hearing loss (SNHL) was calculated as the difference between pre- and post-irradiation values. The pre-irradiation hearing level or patient age was not correlated with the actual SNHL. In contrast, there was a significant correlation between the total radiation dose to the inner ear and the observed hearing impairment. SNHL was most pronounced in the high frequencies, with values up to 35 dB (4000 Hz) and 25 dB (2000 Hz) in some patients. The latent period for the complication appeared to be 12 months or more. The deleterious effect of irradiation on the hearing should be kept in mind both in treatment planning and in the follow-up after radiotherapy.

Grau, Cai; Møller, K

1991-01-01

236

Reported noise-induced hearing loss among miners  

Energy Technology Data Exchange (ETDEWEB)

Virtually all (96.7%) of the reported occupational hearing loss cases in mining are the result of prolonged noise exposure. The remaining cases were the result of explosions, infections, ruptured ear drums, etc. During the past 15 years, 2287 cases of noise-induced hearing loss (NIHL) were reported in the USA. Of these NIHL cases, 68.7% were incurred by coal miners. During the periods from 1980 to 1985 and 1993 to 1994, metal/nonmetal operators reported more NIHL cases than coal operators. Currently there are approximately 80,000 more metal/nonmetal miners than coal miners. The reported number of NIHL cases varied considerably over time, with coal mining showing a greater variability than metal/nonmetal mining, but coal mining showed less variability during the past few years. Coal mining also showed a greater geographic concentration. In metal/nonmetal mining, the variability was not limited to geographic distribution. The distribution of commodities also showed clustering. Despite the limitations of the data and the variability and the phenomena of clustering in both coal and metal/nonmetal reporting, the large number of reported NIHL cases over the past 15 years indicates that NIHL remains a major occupational illness among US miners. 4 refs., 1 figs., 4 tabs.

Valoski, M.P. [US Department of Labor, Mine Safety and Health Administration, Pittsburgh, PA (United States)

1997-12-01

237

The importance of MRI examination for sudden sensorineural hearing loss patients  

International Nuclear Information System (INIS)

Sudden sensorineural hearing loss is commonly knwon as inner ear disease, although little is known about its cause in most cases. We evaluated 383 patients with sudden sensorineural hearing loss using magnetic resonance imaging (MRI). In 8.1% of the patients, MRI examination revealed some abnormal findings that may be associated with sudden sensorineural hearing loss: acoustic tumor was noted in 1%, abnormality of the vertebral-basilar artery in 1%, and infarction around the brainstem in 0.8%. In these cases, using MRI at an early stage of examination, we can establish the correct diagnosis of and treatment for hearing loss. (author)

2009-05-01

238

Sensoryneural hearing loss with predominantly fall in 2000Hz secondary to connexin 26 gene mutation  

Directory of Open Access Journals (Sweden)

Full Text Available Mutations in the connexin 26 gene result in prelocutive sensorineural hearing loss beginning in childhood, usually severe or profound, although it have been reported slight to moderate hearing loss with some mutations. We present the case of a girl who had a hearing loss with predominantly fall in 2000Hz presenting a biallelic mutation in the connexin 26 gene (M34T/N206S. After a review of the findings of our case and in the medical literature we can conclude that patients with prelocutive sensorineural hearing loss in the frequency 2000 Hz require to rule out mutations in the connexin 26 gene like the M34T.

Morales-Angulo C, Cortizo-Vázquez E, Acle-Cervera LM, Sanchís-Picó C, Vergara-Pastrana S.

2012-12-01

239

Temporal and spectral resolution of hearing in patients with precipitous hearing loss: Gap release of masking (GRM) and the role of cognitive function  

DEFF Research Database (Denmark)

The purpose of this experiment was to measure temporal acuity and spectral resolution of hearing in new hearing-aid users over a period of time post-fitting, and to demonstrate the extent to which performance might change over time. For one-octave wide maskers with and without spectral and temporal gaps, masking was measured repeatedly over 3 months post-fitting. GRM was characterized as the release from masking under the gap conditions. The cognitive skills of the participants were assessed with two tests for measuring working memory capacity and lexical vigilance. The results showed that while the masking by one-octave wide noise maskers without any gaps was constant over time, GRM increased over time for maskers involving a temporal gap. Moreover, at low frequencies where the subjects had normal hearing-threshold levels, they performed as hearing-impaired for the spectral-gap condition. For the temporal-gap condition, they performed as normally hearing at both low and high frequencies. These results suggest that patients with precipitous hearing loss do not maintain normal spectral resolution through the low-frequency region, in which the hearing threshold levels are otherwise normal. Surprisingly, the results also showed moderate though highly significant correlation between lexical vigilance and GRM. [Work supported by the William Demant Foundation.] a)Currently at CNBH, Dept. Physiol., University of Cambridge, CB2 3EG Cambridge, UK.

Vestergaard, Martin David

2005-01-01

240

Guest Editorial: Computer-based hearing loss prevention education program for Veterans and military personnel  

Directory of Open Access Journals (Sweden)

Full Text Available According to the Veterans Benefits Administration, more than 672,000 Veterans were service-connected for hearing loss and more than 744,000 Veterans were service-connected for tinnitus as of fiscal year 2010 [1]. Hearing loss and tinnitus are the most prevalent disabilities experienced by Veterans who served during peacetime, Operation Iraqi Freedom/Operation Enduring Freedom, World War II, and the Korean war. In fiscal year 2010, the Department of Veterans Affairs (VA provided 561,212 hearing aids at an estimated cost of $196.7 million and audiological services to Veterans at a cost of $227.4 million.1 Therefore, hearing loss and tinnitus prevention should be a priority for the VA. At least one type of hearing loss—noise-induced hearing loss (NIHL—can be prevented if appropriate protective strategies are implemented.

Robert L. Folmer, PhD

2012-05-01

 
 
 
 
241

High-frequency hearing loss in male farmers of Missouri.  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Farmers are exposed to noise that is potentially hazardous to hearing. We measured the hearing of 161 male farmers and 75 male nonfarmers at the 1979 Missouri Farmers Association Agri-Fair and compared it with the hearing of 129 office workers from central Missouri. Fixed-level screening tests were conducted in both ears at three stimulus frequencies: 1000 and 2000 hertz at 20 decibels hearing level and 4000 hertz at 25 decibels hearing level. Audiometers were calibrated in accordance with th...

Thelin, J. W.; Joseph, D. J.; Davis, W. E.; Baker, D. E.; Hosokawa, M. C.

1983-01-01

242

Training changes processing of speech cues in older adults with hearing loss  

Directory of Open Access Journals (Sweden)

Full Text Available Aging results in a loss of sensory function, and the effects of hearing impairment can be especially devastating due to reduced communication ability. Older adults with hearing loss report that speech, especially in noisy backgrounds, is uncomfortably loud yet unclear. Hearing loss results in an unbalanced neural representation of speech: the slowly-varying envelope is enhanced, dominating representation in the auditory pathway and perceptual salience at the cost of the rapidly-varying fine structure. We hypothesized that older adults with hearing loss can be trained to compensate for these changes in central auditory processing through directed attention to behaviorally-relevant speech sounds. To that end, we evaluated the effects of auditory-cognitive training in older adults (ages 55-79 with normal hearing and hearing loss. After training, the auditory training group with hearing loss experienced a reduction in the neural representation of the speech envelope presented in noise, approaching levels observed in normal hearing older adults. No changes were noted in the control group. Importantly, changes in speech processing were accompanied by improvements in speech perception. Thus, central processing deficits associated with hearing loss may be partially remediated with training, resulting in real-life benefits for everyday communication.

SamiraAnderson

2013-11-01

243

Sudden Hearing Loss as the Initial Manifestation of Chronic Myeloid Leukemia in a Child.  

Directory of Open Access Journals (Sweden)

Full Text Available Hearing loss and blindness rarely occur in patients with chronic myeloid leukemia(CML. In this article, we present a 12-year-old girl who had right-side hearing loss as theinitial manifestation of CML, followed by left-side hearing loss and blindness of the left eyeseveral days after initiating treatment. The initial white cell count was 181,700/mm3.Audiometry showed severe sensorineural hearing loss of her right ear and moderate mixedhearing loss of the left ear. An ophthalmic examination showed optic neuropathy with subhyaloidhemorrhage in the left eye. A brain magnetic resonance image showed minor hemorrhagingin the right lower frontal area and anterior thalamus. These findings might haveimplied leukostasis with hyperviscosity syndrome. She died on the 9th hospital day. Thiscase illustrates that CML should be considered 1 of the rare diagnoses in a patient with suddenonset of hearing loss.

Ching-Chung Tsai

2004-08-01

244

Comparison of Occlusion Effect in Normal Hearing Individuals and those with Slight and Mild Sensory Neural Hearing Loss Via Real Ear Measurement  

Directory of Open Access Journals (Sweden)

Full Text Available Background and Aim: Hearing aid users complain about a phenomenon called "occlusion effect". The aim of this study was to compare the occlusion effect in normal hearing individuals and those with slight and mild sensory neural hearing loss via Real Ear Measurement.Methods: Sixty volunteers (30 male, 30 female aged 18-55 years were enrolled in this study. Subjects were instructed to vocalize /e/ and /i/ for 5 seconds. Sound pressure level was measured by a probe- microphone and recorded in the ear canal. Occlusion effect and the frequency in which maximum occlusion effect occurs were obtained for each individuals for further analysis.Results: The peak of occlusion effect for /e/ was 10.25 dB and 9.77 dB respectively in 751.9 Hz and 542.98 Hz frequencies in female and male individuals. The maximum occlusion effect occurred with 19.03 dB and 19.10 dB for /i/ and in 518.88 Hz and 440.28 Hz in female and male individuals, in respect. In addition, no significant difference was seen among hearing levels and between genders.Conclusion: The peak of occlusion effect varies significantly among hearing aid users so that the hearing aid must be tuned. Probe-microphone measures will assist in determination where frequency- specific adjustments are needed.

Meymaneh Jafari

2011-12-01

245

Synaptic Transmission at the Cochlear Nucleus Endbulb Synapse during Age-Related Hearing Loss in Mice  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Age-related hearing loss (AHL) typically starts from high frequency regions of the cochlea and over time invades lower frequency regions. During this progressive hearing loss, sound-evoked activity in spiral ganglion cells is reduced. DBA mice have an early onset of AHL. In this study, we examined synaptic transmission at the endbulb of Held synapse between auditory nerve fibers and bushy cells in the anterior ventral cochlear nucleus (AVCN). Synaptic transmission in hearing-impaired high fre...

Wang, Yong; Manis, Paul B.

2005-01-01

246

Characteristics of sensorineural hearing loss secondary to inner ear acoustic trauma  

Digital Repository Infrastructure Vision for European Research (DRIVER)

INTRODUCTION Cochlear damage secondary to exposure to acoustic trauma is the consequence of the acoustic energy effects on the hearing cells in Korti's organ. OBJECTIVE The objective was to assess the correlation between the degree of sensorineural hearing loss and the type of audiogram registered in acoustic trauma exposed patients. METHOD We analyzed 262 audiograms of patients exposed to acoustic trauma in correlation to 146 audiograms of patients with cochlear damage and hearing loss not r...

Spremo Slobodan; Stupar Zdenko

2008-01-01

247

The Need for Improved Detection and Management of Adult-Onset Hearing Loss in Australia  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Adult-onset hearing loss is insidious and typically diagnosed and managed several years after onset. Often, this is after the loss having led to multiple negative consequences including effects on employment, depressive symptoms, and increased risk of mortality. In contrast, the use of hearing aids is associated with reduced depression, longer life expectancy, and retention in the workplace. Despite this, several studies indicate high levels of unmet need for hearing health services in older ...

Mcmahon, Catherine M.; Gopinath, Bamini; Schneider, Julie; Reath, Jennifer; Hickson, Louise; Leeder, Stephen R.; Mitchell, Paul; Cowan, Robert

2013-01-01

248

The Protective Efect of Oral Magnesium ion on Noise Induced Hearing Loss  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Introduction: Several animal studies have been performed that demonstrates a relationship between the amount of magnesium ion in the plasma and the hearing thresholds following exposure to noise, Mg++ has been considered as an effective factor in prevention of noise induced hearing loss in animals.The aim of this study was to discover whether Mg for a long period of time have a protective effect on occurrence of Noise Induce Hearing loss.Method: The subjects were randomly chosen among indivi...

Zahra Jafari

1999-01-01

249

Hearing loss in children with very low birth weight: current review of epidemiology and pathophysiology  

Digital Repository Infrastructure Vision for European Research (DRIVER)

An association between birth weight <1500 g (very low birth weight (VLBW)) and hearing loss has been long recognised. As universal hearing screening programmes have become widely implemented and the survival rate of VLBW babies in modern intensive care units has increased, we have gained a substantially better understanding of the nature of this problem. However, many gaps in our knowledge base exist. This review describes recent data on hearing loss in the VLBW population and explains the cu...

2008-01-01

250

Noise-induced hearing loss in workers exposed to urban stressors.  

Science.gov (United States)

The technological and industrial progress together with the intensification of vehicular traffic and the adoption of new social habits are the cause of an increasing noise pollution with possible negative effects on the auditory system. This study aims to assess the noise exposure levels and the effects on the hearing threshold in outdoor and indoor male workers of a big Italian city. The study was carried out on 357 outdoor male workers, exposed to urban noise and on a control group of 357 unexposed indoor workers. Noise levels were measured in 30 outdoor and indoor areas. The subjects underwent tonal liminal audiometry in order to determine the value of their hearing threshold. During their working activity, outdoor and indoor workers are exposed to different noise levels LEX<80 dB(A). At mid-low frequencies (250-2000 Hz), the results show significant differences in the average values of hearing threshold between the two groups in both ears and for all age classes; there are no significant differences between the two groups at higher frequencies. The outdoor noise levels measured are not usually ototoxic and the hearing loss at mid-low frequencies is not characteristic of the exposure to industrial noise. For these reasons the Authors hypothesize that the results may be due to the combined effect of the exposure to noise and to ototoxic air pollutants. The impairment of speech frequencies is disabling and involves the risk of missed forensic recognition. PMID:23811690

Caciari, Tiziana; Rosati, Maria Valeria; Casale, Teodorico; Loreti, Beatrice; Sancini, Angela; Riservato, Roberto; Nieto, Hector A; Frati, Paola; Tomei, Francesco; Tomei, Gianfranco

2013-10-01

251

Mechanisms of radiation-induced sensorineural hearing loss and radioprotection.  

Science.gov (United States)

Patients that receive radiotherapy are at risk of late sensorineural hearing loss when the inner ear is included within the radiation field. Preclinical and human temporal bone studies have shown that there is differential damage to cochlear structures depending on the amount of dose delivered to the inner ear. In vitro studies have suggested that reactive oxygen species (ROS) are the main initial actors in radiation-induced damage. The interaction of ROS with different cellular components can result in different apoptotic pathways. Therefore, approaches to radioprotection are mainly aimed to reduce ROS production through antioxidants. This review summarizes recent research in the field that can improve the understanding and boost preventive efforts of this adverse effect. PMID:24650954

Mujica-Mota, Mario A; Lehnert, Shirley; Devic, Slobodan; Gasbarrino, Karina; Daniel, Sam J

2014-06-01

252

Preliminary speech recognition results after cochlear implantation in patients with unilateral hearing loss: a case series  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Introduction Cochlear implants known to provide support in individuals with bilateral hearing loss may also be of great benefit for individuals with unilateral hearing loss. This case report demonstrates the positive effects of cochlear implantation on speech understanding in noise conditions in patients with unilateral hearing loss and normal hearing on the contralateral side. To the best of our knowledge, the data presented here are from the first few cases to receive a cochlear implant for unilateral hearing loss. Case presentation Four Caucasian German men, two aged 48 and the others aged 51 and 57 years old, with post-lingual unilateral hearing loss and normal hearing on the contralateral side were implanted with a cochlear implant. All our patients were members of the German army. Before and after implantation, they were given a battery of speech tests in different hearing conditions to assess the effect of unilateral cochlear implantation on speech understanding in noise conditions. Test results showed that all patients benefited from unilateral cochlear implantation, particularly in terms of speech understanding in noise conditions. Conclusions Unilateral cochlear implantation might be a successful treatment method for patients with unilateral hearing loss not benefiting from alternative treatment options. The results of this case report open up the field of cochlear implantation for expanded criteria and new areas of research.

Stelzig Yvonne

2011-08-01

253

Profound Bilateral Sensorineural Hearing Loss in Nigerian Children: Any Shift in Etiology?  

Science.gov (United States)

Deafness, profound hearing loss, is a global problem. However, the causes of, attitudes toward, and management options for deafness differ considerably from region to region. This study seeks to identify the present causes of profound sensorineural hearing loss in Nigeria, which in our environment is almost synonymous to a life sentence of silence…

Dunmade, A. D.; Segun-Busari, S.; Olajide, T. G.; Ologe, F. E.

2007-01-01

254

Thyroid carcinoma, cataract and hearing loss in a patient after irradiation for facial hemangioma  

International Nuclear Information System (INIS)

A rare case of a patient irradiated on the right side of the face for a large hemangioma during early childhood is reported. This patient suffers from sensorineural hearing loss in the right ear and a cataract of the right eye, and she underwent surgery for Hurtle cell carcinoma of the thyroid gland. The literature discussing radiation-induced hearing loss is reviewed. (author)

1988-01-01

255

Curing Hearing Loss: Patient Expectations, Health Care Practitioners, and Basic Science  

Science.gov (United States)

Millions of patients are debilitated by hearing loss, mainly caused by degeneration of sensory hair cells in the cochlea. The underlying reasons for hair cell loss are highly diverse, ranging from genetic disposition, drug side effects, traumatic noise exposure, to the effects of aging. Whereas modern hearing aids offer some relief of the symptoms…

Oshima, Kazuo; Suchert, Steffen; Blevins, Nikolas H.; Heller, Stefan

2010-01-01

256

Overcoming Difficulties Experienced in the Work Place by Employees with Occupational Hearing Loss.  

Science.gov (United States)

This paper discusses the industrial sound environment, prevalence of occupational hearing loss (OHL), consequences, ways in which workers cope, and steps to prevent such disabilities and maximize participation of people with OHL in the work setting. The paper shows that hearing loss is concealed, and demanding situations are avoided, resulting in…

Hefu, Raymond; Getty, Louise

1993-01-01

257

76 FR 62093 - Preventing Occupational Hearing Loss: Stakeholder Meeting  

Science.gov (United States)

...including a discussion on personal protective equipment, hearing conservation...subjects as the use of personal protective equipment, effective hearing conservation...concerns with, using personal protective equipment for noise control?...

2011-10-06

258

Fractionated stereotactic radiotherapy of vestibular schwannomas accelerates hearing loss  

DEFF Research Database (Denmark)

To evaluate long-term tumor control and hearing preservation rates in patients with vestibular schwannoma treated with fractionated stereotactic radiotherapy (FSRT), comparing hearing preservation rates to an untreated control group. The relationship between radiation dose to the cochlea and hearing preservation was also investigated.

Rasmussen, Rune; Claesson, Magnus

2012-01-01

259

SLC26A4 mutations in patients with moderate to severe hearing loss.  

Science.gov (United States)

Mutations in SLC26A4 cause either syndromic or nonsyndromic hearing loss. We identified a link between hearing loss and DFNB4 in 3 of the 50 families participating in this study. Sequencing analysis revealed two SLC26A4 mutations, p.V239D and p.S57X, in affected members of the 3 families. These mutations have been previously reported in deaf individuals from the subcontinent, all of whom manifested profound deafness. The patients investigated in our study exhibited moderate to severe hearing loss. Our results show that inactivating SLC26A4 mutations that cause profound deafness can also be involved in the etiology of moderate to severe hearing loss. The type of mutation cannot predict the severity of the hearing loss in all cases, and there may be additional epistatic interactions that could modify the phenotype. PMID:23504402

Khan, Muhammad Riaz; Bashir, Rasheeda; Naz, Sadaf

2013-08-01

260

Hipertensão como fator associado à perda auditiva Hypertension as a factor associated with hearing loss  

Directory of Open Access Journals (Sweden)

Full Text Available OBJETIVO: Identificar possível associação entre hipertensão arterial e perda auditiva. Foi realizado um estudo do tipo caso-controle não pareado, na Universidade Norte do Paraná, no Sul do Brasil. MATERIAL E MÉTODO: 154 casos e 154 controles, de ambos os sexos com idade variando de 45 a 64 anos foram incluídos na pesquisa após o cálculo da amostra. A hipertensão foi verificada por medição da pressão arterial e de questionário sistematizado sobre hipertensão e uso de medicamentos para pressão arterial. A audição foi avaliada por audiometria e anamnese audiológica. A técnica de regressão logística não-condicional foi utilizada com o objetivo de controlar a possível ação de confusão ou modificação de efeito exercida por outras variáveis sobre as associações de interesse. RESULTADOS : Pode-se verificar que existe associação significativa entre hipertensão arterial e presença de perda auditiva e que a perda auditiva observada nesta população sugere que a hipertensão arterial age como fator de aceleração da degeneração do aparelho auditivo proveniente da idade. CONCLUSÕES: Os resultados da presente pesquisa, através da constatação da associação entre hipertensão e perda auditiva, servirão de base a uma integração entre cardiologistas, nefrologistas, otorrinolaringologistas, fonoaudiólogos e outros profissionais da área de com alterações provenientes da hipertensão.AIM: To identify likely association between blood hypertension and hearing loss. Design: A non-paired case-control study. Setting: Institutional work carried out at Universidade Norte do Paraná, in South Brazil. MATERIAL AND METHOD: 154 cases and 154 controls, both genders, aged 45 to 64, included in the research after sample estimation. Methodology: Hypertension was verified through blood pressure readings and by a systematized questionnaire about hypertension and the use of medication for blood pressure. Hearing was assessed through tonal threshold audiometrics and audiologic anamneses. Non-conditional logistic regression was used in order to control likely confusion or modification of effect of other variables on interest associations. RESULTS: There is a significant association between blood hypertension and hearing loss. Hearing loss in the population under study suggests that hypertension is an accelerating factor of degeneration of the hearing apparatus due to aging. CONCLUSIONS: The results in this research, through evidence of association between blood hypertension and hearing loss, can allow for an integrated work of cardiologists, nephrologists, otorhinolaryngologists, audiologists and other health professionals concerned with alterations caused by blood hypertension.

Luciana Lozza de Moraes Marchiori

2006-08-01

 
 
 
 
261

Diagnostic Application of Targeted Resequencing for Familial Nonsyndromic Hearing Loss  

Science.gov (United States)

Identification of causative genes for hereditary nonsyndromic hearing loss (NSHL) is important to decide treatment modalities and to counsel the patients. Due to the genetic heterogeneity in sensorineural genetic disorders, the high-throughput method can be adapted for the efficient diagnosis. To this end, we designed a new diagnostic pipeline to screen all the reported candidate genes for NSHL. For validation of the diagnostic pipeline, we focused upon familial NSHL cases that are most likely to be genetic, rather than to be infectious or environmental. Among the 32 familial NSHL cases, we were able to make a molecular genetic diagnosis from 12 probands (37.5%) in the first stage by their clinical features, characteristic inheritance pattern and further candidate gene sequencing of GJB2, SLC26A4, POU3F4 or mitochondrial DNA. Next we applied targeted resequencing on 80 NSHL genes in the remaining 20 probands. Each proband carried 4.8 variants that were not synonymous and had the occurring frequency of less than three among the 20 probands. These variants were then filtered out with the inheritance pattern of the family, allele frequency in normal hearing 80 control subjects, clinical features. Finally NSHL-causing candidate mutations were identified in 13(65%) of the 20 probands of multiplex families, bringing the total solve rate (or detection rate) in our familial cases to be 78.1% (25/32) Damaging mutations discovered by the targeted resequencing were distributed in nine genes such as WFS1, COCH, EYA4, MYO6, GJB3, COL11A2, OTOF, STRC and MYO3A, most of which were private. Despite the advent of whole genome and whole exome sequencing, we propose targeted resequencing and filtering strategy as a screening and diagnostic tool at least for familial NSHL to find mutations based upon its efficacy and cost-effectiveness.

Gim, Jungsoo; Kim, Ah Reum; Kim, Bong-Jik; Kim, Hyo-Sang; Park, Joo Hyun; Park, Taesung; Oh, Seung-Ha; Han, Kyu-Hee; Park, Woong-Yang

2013-01-01

262

Diagnostic application of targeted resequencing for familial nonsyndromic hearing loss.  

Science.gov (United States)

Identification of causative genes for hereditary nonsyndromic hearing loss (NSHL) is important to decide treatment modalities and to counsel the patients. Due to the genetic heterogeneity in sensorineural genetic disorders, the high-throughput method can be adapted for the efficient diagnosis. To this end, we designed a new diagnostic pipeline to screen all the reported candidate genes for NSHL. For validation of the diagnostic pipeline, we focused upon familial NSHL cases that are most likely to be genetic, rather than to be infectious or environmental. Among the 32 familial NSHL cases, we were able to make a molecular genetic diagnosis from 12 probands (37.5%) in the first stage by their clinical features, characteristic inheritance pattern and further candidate gene sequencing of GJB2, SLC26A4, POU3F4 or mitochondrial DNA. Next we applied targeted resequencing on 80 NSHL genes in the remaining 20 probands. Each proband carried 4.8 variants that were not synonymous and had the occurring frequency of less than three among the 20 probands. These variants were then filtered out with the inheritance pattern of the family, allele frequency in normal hearing 80 control subjects, clinical features. Finally NSHL-causing candidate mutations were identified in 13(65%) of the 20 probands of multiplex families, bringing the total solve rate (or detection rate) in our familial cases to be 78.1% (25/32) Damaging mutations discovered by the targeted resequencing were distributed in nine genes such as WFS1, COCH, EYA4, MYO6, GJB3, COL11A2, OTOF, STRC and MYO3A, most of which were private. Despite the advent of whole genome and whole exome sequencing, we propose targeted resequencing and filtering strategy as a screening and diagnostic tool at least for familial NSHL to find mutations based upon its efficacy and cost-effectiveness. PMID:23990876

Choi, Byung Yoon; Park, Gibeom; Gim, Jungsoo; Kim, Ah Reum; Kim, Bong-Jik; Kim, Hyo-Sang; Park, Joo Hyun; Park, Taesung; Oh, Seung-Ha; Han, Kyu-Hee; Park, Woong-Yang

2013-01-01

263

Deficiência auditiva infantil: implicações e soluções Infantile hearing loss: implications and solutions  

Directory of Open Access Journals (Sweden)

Full Text Available OBJETIVO: promover uma abordagem teórica dos aspectos relevantes a respeito da audição na infância e da detecção precoce da deficiência auditiva infantil. MÉTODOS: foi realizada pesquisa bibliográfica sobre a importância da audição no desenvolvimento infantil, o histórico da detecção precoce da deficiência auditiva infantil e a metodologia usual nos programas de triagem auditiva neonatal. O período de análise foi a partir de 1980 e os descritores utilizados foram deafness, hearing loss, hearing impairment and children. RESULTADOS: a audição é o elemento fundamental para a aquisição e desenvolvimento da linguagem. Muitos são os indicadores de risco que podem afetar a audição nos períodos pré e peri natal. Sendo a detecção precoce um fator determinante para o prognóstico de reabilitação, é de extrema importância a sua efetivação. Existem diferentes metodologias para a detecção da deficiência auditiva, porém os programas de triagem auditiva neonatal que utilizam emissões otoacústicas vêm demonstrando grande aceitação pela sua eficácia e praticidade. CONCLUSÃO: existem graves implicações da deficiência auditiva para o desenvolvimento infantil. A implementação dos programas de triagem auditiva neonatal pode garantir a detecção precoce, o diagnóstico e a reabilitação a tempo de minimizar os efeitos da deficiência auditiva sobre o indivíduo.PURPOSE: to promote a theoretical approach of the relevant aspects regarding the hearing in childhood and the early detection of the infantile hearing loss. METHODS: bibliographical research on the importance of hearing in infantile development, the description of the early detection of the hearing loss and usual methodology in the programs of newborn hearing screening was carried through. The period of analysis went from 1980 and the key-words were deafness, hearing loss, hearing impairment and children. RESULTS: the hearing is the basic element for the acquisition and development of language. Many are the risk indicators that can affect hearing in the pre and peri native periods. Being the early detection a determinative factor for the rehabilitation prognostic, its effectuation is of extreme importance. There are different methodologies for detecting hearing loss, however the programs of newborn hearing screening through otoacoustic emissions have been demonstrating effectiveness and feasibility. CONCLUSION: there are serious implications of hearing loss for infantile development. The implementation of the programs of newborn hearing screening can ensure early detection, diagnosis and rehabilitation in timely-manner to minimize the effect of hearing loss on the subject.

Cladi Inês Gatto

2007-03-01

264

Effect of low-level laser treatment on cochlea hair-cell recovery after ototoxic hearing loss  

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The primary cause of hearing loss includes damage to cochlear hair cells. Low-level laser therapy (LLLT) has become a popular treatment for damaged nervous systems. Based on the idea that cochlea hair cells and neural cells are from same developmental origin, the effect of LLLT on hearing loss in animal models is evaluated. Hearing loss animal models were established, and the animals were irradiated by 830-nm diode laser once a day for 10 days. Power density of the laser treatment was 900 mW/cm2, and the fluence was 162 to 194 J. The tympanic membrane was evaluated after LLLT. Thresholds of auditory brainstem responses were evaluated before treatment, after gentamicin, and after 10 days of LLLT. Quantitative scanning electron microscopic (SEM) observations were done by counting remaining hair cells. Tympanic membranes were intact at the end of the experiment. No adverse tissue reaction was found. On SEM images, LLLT significantly increased the number of hair cells in middle and basal turns. Hearing was significantly improved by laser irradiation. After LLLT treatment, both the hearing threshold and hair-cell count significantly improved.

Rhee, Chung-Ku; He, Peijie; Jung, Jae Yun; Ahn, Jin-Chul; Chung, Phil-Sang; Lee, Min Young; Suh, Myung-Whan

2013-12-01

265

P300 em sujeitos com perda auditiva P300 in subjects with hearing loss  

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Full Text Available TEMA: as avaliações comportamentais e eletrofisiológicas contribuem para o entendimento do sistema auditivo e do processo de intervenção. OBJETIVO: estudar P300 em sujeitos com perda auditiva neurossensorial congênita, segundo as variáveis gênero, idade e grau da perda auditiva. MÉTODO: a presente investigação consiste em um estudo descritivo, transversal. Foram examinados 29 sujeitos, sendo 15 do gênero masculino e 14 do gênero feminino, com idade entre 11 a 42 anos. Os critérios de elegibilidade para composição da amostra foram: idade superior a 11 anos e inferior a 45 anos; ser portador de deficiência auditiva congênita severa ou profunda; não apresentar outro tipo de distúrbio; não apresentar perda auditiva central e/ou comprometimento condutivo. A primeira etapa caracterizou-se por avaliação comportamental auditiva e fisiológica que incluiu: audiometria tonal limiar (via aérea e via óssea, logoaudiometria - LDV e medidas do ganho funcional para os sujeitos que faziam uso de próteses auditivas, Imitanciometria: curva timpanométrica e pesquisa dos reflexos ipsi e contra-laterais, registro das emissões otoacústicas (EOA - emissões otoacústicas transitórias (EOAT e emissões otoacústicas por produto de distorção (EOAPD. A avaliação eletrofisiológica constituiu a quarta etapa do procedimento de coleta de dados e incluiu: potenciais auditivos evocados de tronco encefálico (PEATE e de longa latência (P300. RESULTADOS: o P300 foi registrado em 17 sujeitos, com latência e amplitude média de 326,97ms e 3,76V, respectivamente. Apresentou diferenças significantes da latência em relação à idade (p BACKGROUND: behavioral and electrophysiological evaluations contribute to the understanding of the hearing system and to the intervention process. AIM: to investigate the occurrence of P300 in subjects with congenital severe to profound hearing loss, according to the variables of gender, age and hearing loss level. METHOD: the design of this research is a descriptive transversal study. Twenty-nine subjects, 15 male and 14 female, ranging in age from 11 to 42 years, were evaluated. Inclusion criteria were: to have at least 11 years of age and no more than 45 years; to have the diagnosis of congenital severe to profound sensorineural hearing loss; to have no other disorder; and absence of central hearing loss or any other auditory conductive disorder. The first stage consisted of an auditory behavioral and physiological evaluation, including: pure tone audiometry (air and bone conduction measures, speech audiometry, SDT (Speech Detection Threshold and functional gain measures for the subjects using hearing aids, and immittance measures - tympanometry and acoustic reflexes thresholds; transient evoked otoacoustic emissions (TEOAE; distortion product otoacoustic emissions (DPOAE. The electrophysiological evaluation was the fourth stage of the study and included: auditory brainstem response (ABR and late latency response (P300. RESULTS: P300 was obtained for 17 out of the 29 subjects. Mean latency and amplitude were 326.97 ms and 3.76 V, respectively. A statistical significant difference was observed for latency when considering the variable age (electrode CzA2 p < 0.003 and CzA1 p < 0.02 and for amplitude when considering the variable hearing loss level (p < 0.0015. CONCLUSION: P300 can be recorded in subjects with hearing loss.

Ana Cláudia Mirândola Barbosa Reis

2007-04-01

266

Congenital hearing impairment  

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Establishing the etiology of congenital hearing impairment can significantly improve treatment for certain causes of hearing loss and facilitates genetic counseling. High-resolution CT and MRI have contributed to the evaluation and management of hearing impairment. In addition, with the identification of innumerable genetic loci and genetic defects involved in hearing loss, genetic testing has emerged as an invaluable tool in the assessment of hearing impairment. Some of the common forms of congenital hearing loss are reviewed and their imaging features illustrated. (orig.)

2006-04-01

267

Clinical analysis of post-irradiation sensorineural hearing loss in patients suffering from nasopharyngeal carcinoma  

International Nuclear Information System (INIS)

Objective: To investigate the incidence of post-irradiation sensorineural hearing loss (SNHL) in patients suffering from nasopharyngeal carcinoma and to evaluate its potentially contributing factors. Methods: Pure tonetest and impedance audiography were carried out in patients suffering from nasopharyngeal carcinoma with a post-irradiation follow-up time over 1 year. Additionally, the test results were combined with clinical data and analyzed retrospectively. Results: The follow-up time of all patients ranged from 12 to 94 months (median 53 months). The incidences of SNHL at low and high frequencies were 8% and 42% respectively. Univariate analysis showed that patient's age and follow-up time affected the incidence of SNHL at high frequencies (t=2.051, P=0.0269; t=2.978, P=0.0011), but sex, preirradiation subjective hearing loss, irradiation dose and chemotherapy including cisplatin had no significance. Multivariate analysis by Binary Logistic Regression revealed that the risk of SNHL was correlated with patient's age and follow-up time (P=0.02; P=0.009). Conclusion: Post-irradiation SNHL at high frequencies in patients suffering from nasopharyngeal carcinoma is more common than that at low frequencies. The independent prognostic factors for development of SNHL at high frequencies are patient's age and follow-up time. But the role of preirradiation hearing level ,irradiation dose and chemotherapy including cisplatin are not conclusive and further research is needed. (authors)

2005-06-01

268

The Protective Efect of Oral Magnesium ion on Noise Induced Hearing Loss  

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Full Text Available Introduction: Several animal studies have been performed that demonstrates a relationship between the amount of magnesium ion in the plasma and the hearing thresholds following exposure to noise, Mg++ has been considered as an effective factor in prevention of noise induced hearing loss in animals.The aim of this study was to discover whether Mg for a long period of time have a protective effect on occurrence of Noise Induce Hearing loss.Method: The subjects were randomly chosen among individuals who were under training in army service for two months. The subjects were treated in a double-blind manner by placebo and magnesium ion. Threshold estimation and blood examination was performed for all subjects before and after treatment. All subjects were exposed to noise during 8 weeks training in the army.Results: The statistical difference between two groups which was treated with placebo and magnesium ion was significant.Discussion: This study is compatible with previous in vivo observations and animal studies demonstrating the protective effects of magnesium on noise-induced impairment of inner ear.

Zahra Jafari

1999-03-01

269

Aminoglycoside: induced hearing loss in HIV-positive and HIV-negative multidrug-resistant tuberculosis patients  

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Full Text Available SciELO South Africa | Language: English Abstract in english BACKGROUND: Ototoxicity following aminoglycoside treatment for multidrug-resistant tuberculosis (MDR-TB), is a significant problem. This study documents the incidence of ototoxicity in HIV-positive and HIV-negative patients with MDR-TB and presents clinical guidelines relating to ototoxicity. METHOD [...] S: A prospective cohort study of 153 MDR-TB patients with normal hearing and middle ear status at baseline controlling for 6 mitochondrial mutations associated with aminoglycosiderelated ototoxicity, at Brooklyn Chest Hospital in Cape Town. Pure tone audiometry was performed monthly for 3 months to determine hearing loss. HIV status was recorded, as was the presence of 6 mutations in the MT-RNR1 gene. RESULTS: Fifty-seven per cent developed high-frequency hearing loss. HIV-positive patients (70%) were more likely to develop hearing loss than HIV-negative patients (42%). Of 115 patients who were genetically screened, none had MT-RNR1 mutations. CONCLUSION: Ototoxic hearing loss is common in MDR-TB patients treated with aminoglycosides. HIV-positive patients are at increased risk of ototoxicity. Auditory monitoring and auditory rehabilitation should be an integral part of the package of care of MDR-TB patients.

Tashneem, Harris; Soraya, Bardien; H Simon, Schaaf; Lucretia, Petersen; Greetje, de Jong; Johannes J, Fagan.

270

Biophysical Mechanisms Underlying Hearing Loss Associated with a Shortened Tectorial Membrane  

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The tectorial membrane (TM) connects to the stereociliary bundles of outer hair cells (OHCs). Herein, we summarize key experimental data and modeling analyses that describe how biophysical alterations to these connections underlie hearing loss. The heterozygous C1509G mutation in alpha tectorin produces partial congenital hearing loss that progresses in humans. We engineered this mutation in mice, and histology revealed that the TM was shortened. DIC imaging of freshly-dissected cochlea as well as imaging with optical coherence tomography indicated that the TM is malformed and only stimulates the first row of OHCs. Noise exposure produced acute threshold shifts that fully recovered in Tecta+/+ mice although there was some OHC loss within all three rows at the cochlear base. In contrast, threshold shifts only partially recovered in TectaC1509G/+ mice. This was associated with OHC loss more apically and nearly entirely within the first row. Young's modulus of the TM, measured using atomic force microscopy, was substantially reduced at the middle and basal regions. Both the wild-type and heterozygous conditions were simulated in a computational model. This demonstrated that the normalized stress distribution levels between the TM and the tall cilia were significantly elevated in the middle region of the heterozygous cochlea. Another feature of the TectaC1509G/+ mutation is higher prestin expression within all three rows of OHCs. This increased electricallyevoked movements of the reticular lamina and otoacoustic emissions. Furthermore, electrical stimulation was associated with an increased risk of OHC death as measured by vital dye staining. Together, these findings indicate that uncoupling of the TM from some OHCs not only leads to partial hearing loss, but also puts the OHCs that remain coupled at higher risk. Both the mechanics of the malformed TM and increased electromotility contribute to this higher risk profile.

Oghalai, John S.; Xia, Anping; Liu, Christopher C.; Gao, Simon S.; Applegate, Brian E.; Puria, Sunil; Rousso, Itay; Steele, Charles

2011-11-01

271

Tinnitus as an early indicator of permanent hearing loss. A 15 year longitudinal study of noise exposed workers.  

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A retrospective study was designed to evaluate tinnitus (ringing or other sounds in the ears or head) as a potential early indicator of permanent hearing loss in a population of noise exposed workers. Data were examined from 91 male employees working in environments with noise levels ranging from 8 hour time weighted averages of 85 to 101 dBA over a period of 15 years. Results of annual audiometric testing were obtained as part of an ongoing hearing conservation program conducted since 1971 by ESCO Corporation, a steel foundry located in the Portland, Oregon metropolitan area. Results indicate the prevalence of tinnitus increases more than two and one half times for workers experiencing maximum threshold shifts > or = 15 decibels in hearing level (dBHL). Results also provide evidence that reports of tinnitus at the time of annual audiometric testing may be useful in identifying workers at greater risk for developing significant shifts in hearing thresholds. PMID:9748912

Griest, S E; Bishop, P M

1998-07-01

272

Hearing Loss due to Infiltration of the Tympanic Membrane by Chronic Lymphocytic Leukemia  

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Central nervous system (CNS) involvement by chronic lymphocytic leukemia (CLL) can present with dramatic neurologic findings or can be quite subtle, discovered only at the time of autopsy. We describe a case of CLL in a patient who presented initially with hearing loss and was ultimately found to have involvement of the tympanic membrane. She noted improvement of her hearing after induction therapy but was not aware at the time of the involvement of her CNS with CLL. Upon worsening of hearing...

2012-01-01

273

Acute sensorineural hearing loss and severe otalgia due to scrub typhus  

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Full Text Available Abstract Background Scrub typhus is an acute febrile illness caused by Orientia tsutsugamushi. Case presentations We encountered a patient with sensorineural hearing loss complicating scrub typhus, and three patients with scrub typhus who complained of otalgia, which was sudden onset, severe, paroxysmal, intermittent yet persistent pain lasting for several seconds, appeared within 1 week after the onset of fever and rash. The acute sensorineural hearing loss and otalgia were resolved after antibiotic administration. Conclusion When patients in endemic areas present with fever and rash and have sensorineural hearing loss or otalgia without otoscopic abnormalities, clinicians should suspect scrub typhus and consider empirical antibiotic therapy.

Kim Dong-Min

2009-10-01

274

Molecular screening of patients with nonsyndromic hearing loss from Nanjing city of China?  

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Hearing loss is the most frequent sensory disorder involving a multitude of factors, and at least 50% of cases are due to genetic etiology. To further characterize the molecular etiology of hearing loss in the Chinese population, we recruited a total of 135 unrelated patients with nonsyndromic sensorineural hearing loss (NSHL) for mutational screening of GJB2, GJB3, GJB6, SLC26A4, SLC26A5 IVS2-2A>G and mitochondrial 12SrRNA, tRNASer(UCN) by PCR amplification and direct DNA sequencing. The car...

2011-01-01

275

An epidemiological perspective of the causes of hearing loss among industrial workers.  

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An etiologic paradigm of hearing loss for industrial workers is introduced as having two major components, one being occupational and the other extra-occupational. The extra-occupational factors include age, noise exposure outside the work place, trauma, ear disease and ototoxic drugs. The work-related factors include occupational noise, whole body vibration, work-related diseases and toxic exposures. Within this framework, a review of the epidemiology of hearing loss examines the possible relationships between hearing loss and these factors. PMID:2179575

Phaneuf, R; Hétu, R

1990-02-01

276

The association between low levels of lead in blood and occupational noise-induced hearing loss in steel workers  

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As the use of leaded gasoline has ceased in the last decade, background lead exposure has generally been reduced. The aim of this study was to examine the effect of low-level lead exposure on human hearing loss. This study was conducted in a steel plant and 412 workers were recruited from all over the plant. Personal information such as demographics and work history was obtained through a questionnaire. All subjects took part in an audiometric examination of hearing thresholds, for both ears, with air-conducted pure tones at frequencies of 500, 1000, 2000, 3000, 4000, 6000 and 8000 Hz. Subjects' blood samples were collected and analyzed for levels of manganese, copper, zinc, arsenic, cadmium and lead with inductive couple plasma-mass spectrometry. Meanwhile, noise levels in different working zones were determined using a sound level meter with A-weighting network. Only subjects with hearing loss difference of no more than 15 dB between both ears and had no congenital abnormalities were included in further data analysis. Lead was the only metal in blood found significantly correlated with hearing loss for most tested sound frequencies (p < 0.05 to p < 0.0001). After adjustment for age and noise level, the logistic regression model analysis indicated that elevated blood lead over 7 {mu}g/dL was significantly associated with hearing loss at the sound frequencies of 3000 through 8000 Hz with odds ratios raging from 3.06 to 6.26 (p < 0.05 {approx} p < 0.005). We concluded that elevated blood lead at level below 10 {mu}g/dL might enhance the noise-induced hearing loss. Future research needs to further explore the detailed mechanism.

Hwang, Yaw-Huei [Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei, Taiwan, ROC Rm. 735, 17, Xu-Zhou Rd., Taipei, Taiwan, ROC (China); Department of Public Health, College of Public Health, National Taiwan University, Taipei, Taiwan, ROC Rm. 735, 17, Xu-Zhou Rd., Taipei, Taiwan, ROC (China); Chiang, Han-Yueh [Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei, Taiwan, ROC Rm. 735, 17, Xu-Zhou Rd., Taipei, Taiwan, ROC (China); Yen-Jean, Mei-Chu [Division of Family Medicine, E-Da Hospital, Taiwan, ROC 1, E-Da Rd., Jiau-Shu Tsuen, Yan-Chau Shiang, Kaohsiung County, Taiwan, ROC (China); I-Shou University, Kaohsiung County, Taiwan, ROC 1, Sec. 1, Syuecheng Rd., Da-Shu Shiang, Kaohsiung County, Taiwan, ROC (China); Wang, Jung-Der, E-mail: jdwang@ntu.edu.tw [Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei, Taiwan, ROC Rm. 735, 17, Xu-Zhou Rd., Taipei, Taiwan, ROC (China); Department of Public Health, College of Public Health, National Taiwan University, Taipei, Taiwan, ROC Rm. 735, 17, Xu-Zhou Rd., Taipei, Taiwan, ROC (China); Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, ROC No. 1, Chang-Teh St., Taipei, Taiwan, ROC (China)

2009-12-15

277

The association between low levels of lead in blood and occupational noise-induced hearing loss in steel workers  

International Nuclear Information System (INIS)

As the use of leaded gasoline has ceased in the last decade, background lead exposure has generally been reduced. The aim of this study was to examine the effect of low-level lead exposure on human hearing loss. This study was conducted in a steel plant and 412 workers were recruited from all over the plant. Personal information such as demographics and work history was obtained through a questionnaire. All subjects took part in an audiometric examination of hearing thresholds, for both ears, with air-conducted pure tones at frequencies of 500, 1000, 2000, 3000, 4000, 6000 and 8000 Hz. Subjects' blood samples were collected and analyzed for levels of manganese, copper, zinc, arsenic, cadmium and lead with inductive couple plasma-mass spectrometry. Meanwhile, noise levels in different working zones were determined using a sound level meter with A-weighting network. Only subjects with hearing loss difference of no more than 15 dB between both ears and had no congenital abnormalities were included in further data analysis. Lead was the only metal in blood found significantly correlated with hearing loss for most tested sound frequencies (p < 0.05 to p < 0.0001). After adjustment for age and noise level, the logistic regression model analysis indicated that elevated blood lead over 7 ?g/dL was significantly associated with hearing loss at the sound frequencies of 3000 through 8000 Hz with odds ratios raging from 3.06 to 6.26 (p < 0.05 ? p < 0.005). We concluded that elevated blood lead at level below 10 ?g/dL might enhance the noise-induced hearing loss. Future research needs to further explore the detailed mechanism.

2009-12-15

278

[Genetic study of hearing loss in families from Argentina].  

Science.gov (United States)

Recent advances in molecular genetics as well as improved strategies for the prevention and control of non-syndromic hearing loss (NSHL) have contributed to the rising importance of their inherited causes. In this study we report 32 families from Argentine with one (sporadic) or more (familial) individuals affected. All the families were initially screened for mutations in three autosomal nuclear genes and one mutation in mitochondrial DNA. These genes have been found in a great number of familial or sporadic cases of congenital deafness in Caucasians. The mutant allele 35 del G of connexin 26 (GJB2, locus DFNB1 on 13q12) was present in three families. We have investigated the gene encoding otoferlin (OTOF, locus DFNB9 on 2p22-p23) and we found the Q829X mutation in heterocigosity in two families. We have also identified in heterocigosity the 342-kb deletion of connexin 30 (GJB6, locus DFNB1 on 13q12) in one family. On the other hand, we have not found any patient with mitochondrial mutation. Since the screening for other mutations is very expensive, our main goal is to investigate the most frequent mutations in each separate gene in the argentine population and to develop simple and specific tests for each frequent mutations. PMID:15366230

Reynoso, Raúl A; Hendl, Silvia; Barteik, Marìa E; Curet, Carlos A; Nicemboin, Luis; Moreno Barral, José; Rodríguez Ballesteros, Montserrat; Del Castillo, Ignacio; Moreno, Felipe

2004-01-01

279

A rare novel mutation in TECTA causes autosomal dominant nonsyndromic hearing loss in a Mongolian family  

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Background The genetic basis of autosomal dominant nonsyndromic hearing loss is complex. Genetic factors are responsible for approximately 50% of cases with congenital hearing loss. However, no previous studies have documented the clinical phenotype and genetic basis of autosomal dominant nonsyndromic hearing loss in Mongolians. Methods In this study, we performed exon capture sequencing of a Mongolian family with hereditary hearing loss and identified a novel mutation in TECTA gene, which encodes ? -tectorin, a major component of the inner ear extracellular matrix that contacts the specialized sensory hair cells. Results The novel G???T missense mutation at nucleotide 6016 results in a substitution of amino acid aspartate at 2006 with tyrosine (Asp2006Tyr) in a highly conserved zona pellucida (ZP) domain of ?-tectorin. The mutation is not found in control subjects from the same family with normal hearing and a genotype-phenotype correlation is observed. Conclusion A novel missense mutation c.6016 G?>?T (p.Asp2006Tyr) of TECTA gene is a characteristic TECTA-related mutation which causes autosomal dominant nonsyndromic hearing loss. Our result indicated that mutation in TECTA gene is responsible for the hearing loss in this Mongolian family.

2014-01-01

280

Cochlear Implants in Children with Hearing Loss: Maternal Expectations and Impact on the Family  

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To facilitate evaluations of cochlear implant candidates and to promote (re)habilitation efficacy and collaboration with families, this study examined the expectations of 35 mothers with typical hearing and their beliefs and difficulties related to their child's hearing loss and current or future cochlear implantation. Questionnaires measured…

Zaidman-Zait, Anat; Most, Tova

2005-01-01

 
 
 
 
281

Qualitative analysis of parents' experience with early detection of hearing loss  

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Aims: To determine key themes from parents' comments on paths to diagnosis and intervention for their children with hearing loss, following introduction of at-risk neonatal hearing screening and modification of distraction test screening for infants not at-risk.

2004-01-01

282

Early Hearing Loss and Language Abilities in Children with Down Syndrome  

Science.gov (United States)

Background: Although many children with Down syndrome experience hearing loss, there has been little research to investigate its impact on speech and language development. Studies that have investigated the association give inconsistent results. These have often been based on samples where children with the most severe hearing impairments have…

Laws, Glynis; Hall, Amanda

2014-01-01

283

Noise-induced hearing loss : prevalence, degree and impairment criteria in South African gold miners  

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Despite the preventability of noise-induced hearing loss (NIHL) a high prevalence is still reported in South African mines. The study aimed to describe the hearing of gold miners pertaining to the prevalence and degree of NIHL and effectiveness of current RSA impairment criteria to identify NIHL.

2013-01-01

284

Vocabulary Development in Children with Hearing Loss: The Role of Child, Family, and Educational Variables  

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In the present study we examined the effect of hearing status on reading vocabulary development. More specifically, we examined the change of lexical competence in children with hearing loss over grade 4-7 and the predictors of this change. Therefore, we used a multi-factor longitudinal design with multiple outcomes, measuring the reading…

Coppens, Karien M.; Tellings, Agnes; van der Veld, William; Schreuder, Robert; Verhoeven, Ludo

2012-01-01

285

School Nurses' Role in Identifying and Referring Children at Risk of Noise-Induced Hearing Loss  

Science.gov (United States)

Young people are likely to experience noise-induced hearing loss (NIHL), as the use of personal listening devices and other damaging factors (e.g., video games) increases. Little research has examined the role of school health personnel in the prevention and early identification of hearing impairment. A 32-item, valid and reliable survey was…

Hendershot, Candace; Pakulski, Lori A.; Thompson, Amy; Dowling, Jamie; Price, James H.

2011-01-01

286

Is sensorineural hearing loss a possible side effect of nasopharyngeal and parotid irradiation? A systematic review of the literature  

International Nuclear Information System (INIS)

Background and purpose: Little has been published about permanent hearing loss due to radiotherapy, thus making it a rather unknown phenomenon. Therefore, we performed a study of the literature over the last 20 years. Materials and methods: Sixteen relevant clinical studies were found, reporting mostly on nasopharyngeal or parotid gland treatments. Hearing loss was measured using a pure tone audiogram. Studies were assessed using a simple scoring list. Nine studies were used for further analysis. Data on the pure tone audiogram were pooled. Results: Results showed that, especially in the higher frequencies (?4 kHz), loss can be measured. When data were pooled, in 42±3% of the patients a hearing loss was found of 10 dB or more at 4 kHz. Averaged over all measured frequencies the effect is less prominent but still statistically significant (18±2%). No significant difference between nasopharyngeal and parotid gland treatment was found (P<0.05). Conclusion: Only a few studies, mostly concerning small patient numbers, have investigated hearing damage due to radiotherapy. So far there has been no consensus on the subject. However, in this systematic review we found a significant effect. Dose to the inner ear therefore deserves more attention, especially in dose escalation studies and inverse planning

2002-10-01

287

[Electrocochleography possibilities in the differential diagnosis of hydrops and neural hearing loss].  

Science.gov (United States)

Enhancement of the click-evoked summating potential causing a pathological summation to compound action potential ratio (SP/CAP) in patients with endolymphatic hydrops has been described by several groups. An increased SP/CAP ratio is found also in some patients with a tumour of the cerebellopontine angle. The study of further parameters of the SP/CAP complex, such as the CAP latency and the width of the complex, permit an electrocochleographic differentiation between both forms of hearing loss. The N2 amplitude showed no diagnostic significance. PMID:2318669

Marangos, N; Mausolf, A; Ziesmann, B

1990-02-01

288

Sensori-neural hearing loss after radiotherapy for nasopharyngeal carcinoma: individualized risk estimation  

International Nuclear Information System (INIS)

Background and purpose: Sensori-neural hearing loss (SNHL) is a common complication to radiation therapy in the upper head and neck region. In this study, we estimated the dose response relationship for SNHL with adjustment for pre-therapeutic risk factors. Patients and methods: The pre- and post-therapeutic hearing levels were recorded in a previously published study of 20 patients receiving radiotherapy for nasopharyngeal carcinoma. In the present study, the dose to the inner ear of these patients was estimated with a computed tomography (CT) based treatment planning system. CT data from a 'proxy patient' were used for patients with no available CT scan. SNHL was analyzed as a function of radiation dose and potential risk factors were tested. Results: The incidence of SNHL increased significantly with increasing dose to the cochlea. Increasing patient's age, and decreasing pre-therapeutic hearing level were statistically significantly associated with an increased risk of SNHL. A nomogram is presented for estimating individualized dose constraints of potential use in treatment planning. Conclusions: The inner ear is a critical structure in patients with nasopharyngeal carcinoma and the dose to the inner ear should be carefully considered when planning radiation treatment in this region

2002-10-01

289

The Treatment of Idiopathic Sudden Sensorineural Hearing Loss Using Phle-botomy: A Prospective, Randomized, Double-Blind Clinical Trial  

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Full Text Available This randomized clinical trial aimed to assess the efficacy of phlebotomy on improvement of hearing loss. 71 patients with sudden sensorineural hearing loss were enrolled in this randomized clinical trial study. They were divided into two groups: group A received steroid and hydration therapy plus phlebotomy, while group B received the same regimen without phlebotomy. They were matched according to sex, age, Hb, and Htc. Pure tone audiometries were administered to examine the hearing levels before and after treatment. Statistical analysis showed higher improvement in 250-1000 Hz in patients whit phlebotomy (P<0.001. However, there was noticed no significant difference in hearing improvement in 2000-8000 Hz between two methods. The number (% of patients who had improvement was 29(85.3% in phlebotomy group and 21(56.8% in non-phlebotomy group. On the other hand, the number (% of patients who showed no improvement in A and B group was 5(14.7% and 16(43.2%, respectively (P=0.008. Using phlebotomy accompanied by steroid and hydration therapy leads to higher improvement in hearing loss especially in 250-1000 Hz. We think that this method has the ability to achieve better result in the management of patients with SSNHL.

Mohammad Taghi Goodarzi

2009-12-01

290

The cultural and linguistic diversity of 3-year-old children with hearing loss.  

Science.gov (United States)

Understanding the cultural and linguistic diversity of young children with hearing loss informs the provision of assessment, habilitation, and education services to both children and their families. Data describing communication mode, oral language use, and demographic characteristics were collected for 406 children with hearing loss and their caregivers when children were 3 years old. The data were from the Longitudinal Outcomes of Children with Hearing Impairment (LOCHI) study, a prospective, population-based study of children with hearing loss in Australia. The majority of the 406 children used spoken English at home; however, 28 other languages also were spoken. Compared with their caregivers, the children in this study used fewer spoken languages and had higher rates of oral monolingualism. Few children used a spoken language other than English in their early education environment. One quarter of the children used sign to communicate at home and/or in their early education environment. No associations between caregiver hearing status and children's communication mode were identified. This exploratory investigation of the communication modes and languages used by young children with hearing loss and their caregivers provides an initial examination of the cultural and linguistic diversity and heritage language attrition of this population. The findings of this study have implications for the development of resources and the provision of early education services to the families of children with hearing loss, especially where the caregivers use a language that is not the lingua franca of their country of residence. PMID:22942315

Crowe, Kathryn; McLeod, Sharynne; Ching, Teresa Y C

2012-01-01

291

Clinical and experimental studies on the sensorineural hearing loss caused by irradiation  

International Nuclear Information System (INIS)

In our study, 43 patients whose ears were presumably irradiated, were examined periodically before and after the irradiation; 10 were found to be affected by the sensorineural hearing loss, and these 10 were classified into two types. Type I; Patients of this group had a hearing impairment during or soon after irradiation and usually revealed marked deterioration of bone conduction in high frequencies accompanied by worsening of air conduction in low frequencies. The impaired hearing of this group soon recovered to the pre-treatment level. Type II; Patients of this group developed a slow progressive sensorineural hearing loss. They noticed the deafness with tinnitus several months after irradiation. To clarify the mechanism of the sensorineural hearing loss, histopathological investigations were done using nembutal anesthetized guinea pigs which were irradiated in the confined ear region unilaterally. We also examined histopathologically one human temporal bone belonging to a patient who had been irradiated for middle ear carcinoma. The histopathology of the guinea pigs and human case revealed the following conclusions: Type I hearing loss may be caused by toxic labyrinthitis secondary to the radiation otitis media or by the aseptic labyrinthitis as the result of hyperemia and increased permeability of the irradiated blood vessels in the cochlea. Type II hearing loss may be caused by the late rediation response of the cochleal blood vessels i.e. by the vasculitis which gives rise to obliteration of the vascular lumen and affects the blood supply of the hair cells. (author)

1979-08-01

292

Resolução temporal em perdas auditivas sensorioneurais / Temporal resolution in sensorineural hearing loss  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese OBJETIVO: Avaliar a resolução temporal em adultos com perdas auditivas sensorioneurais de graus leve e moderado, por meio do teste Gaps in Noise (GIN), a fim de verificar se essas perdas influenciam no desempenho do teste. MÉTODOS: Foram avaliados 57 pacientes, com idades entre 20 e 59 anos (30 home [...] ns e 27 mulheres), que realizaram anamnese, avaliação otorrinolaringológica, avaliação audiológica básica e triagem do processamento auditivo, com o teste Dicótico de Dígitos. Os sujeitos foram alocados nos grupos G1 (audição normal), G2 (perda auditiva leve) e G3 (perda moderada). Foi realizada análise estatística apropriada e o nível de significância adotado foi de 5%. RESULTADOS: Observou-se presença significativa de homens no grupo com perda auditiva. Não foram encontradas diferenças significativas no desempenho do referido teste entre os grupos. Porém, no grupo controle, foram observados piores desempenhos, quando comparados com o critério de normalidade previsto para adultos jovens brasileiros. A média do limiar de detecção de gaps, da amostra geral, foi de 8,2 ms, em ambas as orelhas, e a média das porcentagens de acertos foi de 49,7% para a orelha direita (OD) e de 50,6% para a orelha esquerda (OE). CONCLUSÃO: A habilidade de resolução temporal avaliada pelo teste GIN não sofre influência da perda auditiva sensorioneural de graus leve e moderado, tanto nos limiares de detecção de gaps quanto na porcentagem de acertos, em ambas as orelhas. Abstract in english PURPOSE: To evaluate temporal resolution in adults with mild and moderate sensorineural hearing loss using the Gaps in Noise (GIN) test to determine whether these losses affect the test performance. METHODS: Fifty-seven patients between 20 and 59 years of age (30 men and 27 women) were evaluated; th [...] ese patients had a complete medical history taken and underwent ENT examination, basic audiological evaluation, and auditory screening via the dichotic digits test. The subjects were divided into three groups: G1 (normal hearing), G2 (mild hearing loss), and G3 (moderate hearing loss). The appropriate statistical analysis was performed, and the adopted level of significance was 5%. RESULTS: A significant proportion of men was observed in the group with hearing loss. There were no significant differences in test performance between the groups. However, the control group's performance was worse than the normality criteria set for young Brazilian adults. The mean gap detection threshold for the total sample was 8.2 ms in both ears, and the mean percentage of correct responses was 49.7% for the right ear (RE) and 50.6% for the left ear (LE). CONCLUSION: The temporal resolution evaluated by the GIN test was not influenced by mild-to-moderate sensorineural hearing loss either in the gap detection thresholds or in the percentage of correct responses for both ears.

Giselle Goulart de Oliveira, Matos; Silvana, Frota.

293

Hearing Impairment  

Science.gov (United States)

... gets to your brain. Back Continue What Is Hearing Impairment? Hearing impairment occurs when there's a problem with ... most common birth anomaly. Back Continue What Causes Hearing Impairment? The most common cause of conductive hearing loss ...

294

Sensori-neural hearing loss after radiotherapy for nasopharyngeal carcinoma: individualized risk estimation  

DEFF Research Database (Denmark)

Sensori-neural hearing loss (SNHL) is a common complication to radiation therapy in the upper head and neck region. In this study, we estimated the dose response relationship for SNHL with adjustment for pre-therapeutic risk factors.

Honoré, Henriette B; Bentzen, Søren

2002-01-01

295

78 FR 53702 - Computation of, and Rules Relating to, Medical Loss Ratio; Hearing Cancellation  

Science.gov (United States)

...DEPARTMENT OF THE TREASURY Internal Revenue Service 26 CFR Part 1 [REG-126633-12] RIN 1545-BL05 Computation of, and Rules Relating to, Medical Loss Ratio; Hearing Cancellation AGENCY: Internal Revenue Service (IRS),...

2013-08-30

296

A p.C343S Missense Mutation in PJVK causes Progressive Hearing Loss  

Science.gov (United States)

Mutations in PJVK, encoding Pejvakin, cause autosomal recessive nonsyndromic hearing loss in humans at the DFNB59 locus on chromosome 2q31.2. Pejvakin is involved in generating auditory and neural signals in the inner ear. We have identified a consanguineous Pakistani family segregating sensorineural progressive hearing loss as a recessive trait, consistent with linkage to DFNB59. We sequenced PJVK and identified a novel missense mutation, c.1028 G>C in exon 7 (p.C343S) co-segregating with the phenotype in the family. The p.C343 residue is fully conserved among orthologs from different vertebrate species. We have also determined that mutations in PJVK are not a common cause of hearing loss in families with moderate to severe hearing loss in Pakistan. This is the first report of PJVK mutation in a Pakistani family and pinpoints an important residue for PJVK function.

Mujtaba, Ghulam; Bukhari, Ihtisham; Fatima, Amara; Naz, Sadaf

2012-01-01

297

Hearing Loss After Radiotherapy for Pediatric Brain Tumors: Effect of Cochlear Dose  

International Nuclear Information System (INIS)

Purpose: To determine the effect of cochlear dose on sensorineural hearing loss in pediatric patients with brain tumor treated by using conformal radiation therapy (CRT). Patients and Methods: We studied 78 pediatric patients (155 ears) with localized brain tumors treated in 1997-2001 who had not received platinum-based chemotherapy and were followed up for at least 48 months. They were evaluated prospectively by means of serial pure-tone audiograms (250 Hz-8 kHz) and/or auditory brainstem response before and every 6 months after CRT. Results: Hearing loss occurred in 14% (11 of 78) of patients and 11% (17 of 155) of cochleae, with onset most often at 3-5 years after CRT. The incidence of hearing loss was low for a cochlear mean dose of 30 Gy or less and increased at greater than 40-45 Gy. Risk was greater at high frequencies (6-8 kHz). In children who tested abnormal for hearing, average hearing thresholds increased from a less than 25 decibel (dB) hearing level (HL) at baseline to a mean of 46 ± 13 (SD) dB HL for high frequencies, 41 ± 7 dB HL for low frequencies, and 38 ± 6 dB HL for intermediate frequencies. Conclusions: Sensorineural hearing loss is a late effect of CRT. In the absence of other factors, including ototoxic chemotherapy, increase in cochlear dose correlates positively with hearing loss in pediatric patients with brain tumor. To minimize the risk of hearing loss for children treated with radiation therapy, a cumulative cochlear dose less than 35 Gy is recommended for patients planned to receive 54-59.4 Gy in 30-33 treatment fractions

2008-11-01

298

Discrepancy in improvement of hearing loss between left and right ears after postmenopausal hormone therapy.  

Science.gov (United States)

Physiological levels of estrogen would seem to have a possible protective effect on hearing function and estrogen replacement therapy may delay hearing loss in menopausal women. Treatment of healthy menopausal women with Tibolone for 6 months resulted in improvement in audiometry results at low frequencies which was more prominent on the right side. The reason of better improvement on the right side is not known. There might be some other factors modifying the condition or effect of the drug such as laterality. There might be hearing lateralization in menopausal women. Especially significant improvement on right ear might be explained by differences in distribution of estrogen receptor (ER) in the ear, in another words lateralization of ER concentration. ER-? and -? might be more dense in the right ear, so give better response to estrogen treatment. Another reason might be difference in bone mineral density of sides of body which is lower on the right side. Similarly lower bone mineral density right ear bones would cause better response to estrogen therapy and better improvement in audiometry results on that side. PMID:21134720

Kö?ü?, Nermin; Kö?ü?, Aydin; Turhan, Nilgün Ö

2011-03-01

299

The ability of adolescents with hearing loss in special schools to access and use academic information  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Access and use of academic information by adolescents with hearing loss is important to assure their academic success. Learners with hearing loss experience problems regarding communication, literacy, and information literacy, which has an impact on their ability to access and use various types of academic information sources. This leads to problems in achieving tertiary education and employment in later life. In order for learners to develop their abilities and skills to access and use acade...

2010-01-01

300

Coronary artery bypass grafting and sensorineural hearing loss, a cohort study  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Abstract Background Sudden sensorineural hearing loss is routinely encountered by the otologist. The etiology is varied and often identifiable. One of the relatively less frequent causes is surgery. Apart from being an established entity with otological surgeries, sensorineural hearing loss has also been known to occur after non-otological procedures under general anesthesia. Commonest amongst these procedures is cardiopulmonary bypass, an association that has long been recog...

Ashraf Omer

2005-01-01

 
 
 
 
301

Hyperbaric Oxygen Therapy for Sudden Sensorineural Hearing Loss after Failure from Oral and Intratympanic Corticosteroid  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Systemic and intratympanic steroids are most widely used for treating idiopathic sudden sensorineural hearing loss. Other treatments include vasodilator, immunosuppressant and antiviral medication. However, only 61% of patients achieve full recovery, and controversies about the standard treatment still exist. In this case report, we present a patient with idiopathic sudden sensorineural hearing loss who failed to respond to systemic and intratympanic steroid treatments but subsequently recove...

Imsuwansri, Thanarath; Poonsap, Pipat; Snidvongs, Kornkiat

2012-01-01

302

Detection of Mutations in Genes Associated with Hearing Loss Using a Microarray-Based Approach  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Knowing the etiology of hearing loss in a person has implications for counseling and management of the condition. More than 50% of cases of early onset, nonsyndromic sensorineural hearing loss are attributable to genetic factors. However, deafness is a genetically heterogeneous condition and it is therefore currently not economically and practically feasible to screen for mutations in all known deafness genes. We have developed a microarray-based hybridization biochip assay for the detection ...

Siemering, Kirby; Manji, Shehnaaz S. M.; Hutchison, Wendy M.; Du Sart, Desiree; Phelan, Dean; Dahl, Hans-henrik M.

2006-01-01

303

A connexin 26 mutation causes a syndrome of sensorineural hearing loss and palmoplantar hyperkeratosis (MIM 148350)  

Digital Repository Infrastructure Vision for European Research (DRIVER)

We report a missense mutation in the connexin 26 gene (GJB2) in a family with an autosomal dominant syndrome of hearing loss and hyperkeratosis. The affected family members have high frequency, slowly progressive, bilateral, sensorineural hearing loss and palmoplantar hyperkeratosis. The mutation causes an amino acid substitution (G59A), which may disrupt a reverse turn in the first extracellular loop of connexin 26. Connexin 26 mutations have been reported in syndromes of deafness and pal...

Heathcote, K.; Syrris, P.; Carter, N.; Patton, M.

2000-01-01

304

Idiopathic Sudden Sensorineural Hearing Loss in Sweden : Diagnostic Protocol and Treatment in Relation to Outcome  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Idiopathic Sudden Sensorineural Hearing Loss (ISSNHL) is a rapid loss of hearing caused by damage to the cochlea (inner ear) or auditory nerve. Spontaneous recovery has been seen in 32% - 81%. The incidence of the ISSNHL has been estimated to be between 5 and 20 per 100,000 per year. Different theories (infections, vascular catastrophes, immunologic damage or intracochlear membrane break) about the etiology have resulted in different treatment policies. The effect of therapy is difficult to e...

Nosrati-zarenoe, Ramesh

2009-01-01

305

Idiopathic Sudden Sensorineural Hearing Loss : Corticosteroid Treatment, the Diagnostic Protocol and Outcome  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Idiopathic Sudden Sensorineural Hearing Loss (ISSNHL) is a rapid loss of hearing caused by damage to the cochlea or auditory nerve. Spontaneous recovery has been seen in 32%–81%. The incidence of the ISSNHL has been estimated to be between 5 and 20 per 100,000 per year. Different theories (vascular catastrophes, immunologic damage, infections or intracochlear membrane break) about the etiology have resulted in different treatment policies. The effect of therapy is difficult to evaluate for ...

Nosrati-zarenoe, Ramesh

2011-01-01

306

Tumor necrosis factor-alpha-mutant mice exhibit high frequency hearing loss.  

Science.gov (United States)

Exogenous tumor necrosis factor-alpha (TNF-?) plays a role in auditory hair cell death by altering the expression of apoptosis-related genes in response to noxious stimuli. Little is known, however, about the function of TNF-? in normal hair cell physiology. We, therefore, investigated the cochlear morphology and auditory function of TNF-?-deficient mice. Auditory evoked brainstem response showed significantly higher thresholds, especially at higher frequencies, in 1-month-old TNF-?(-/-) mice as compared to TNF-?(+/-) and wild type (WT); hearing loss did not progress further from 1 to 4 months of age. There was no difference in the gross morphology of the organ of Corti, lateral wall, and spiral ganglion cells in TNF-?(-/-) mice compared to WT mice at 4 months of age, nor were there differences in the anatomy of the auditory ossicles. Outer hair cells were completely intact in surface preparations of the organ of Corti of TNF-?(-/-) mice, and synaptic ribbon counts of TNF-?(-/-) and WT mice at 4 months of age were similar. Reduced amplitudes of distortion product otoacoustic emissions, however, indicated dysfunction of outer hair cells in TNF-?(-/-) mice. Scanning electron microscopy revealed that stereocilia were sporadically absent in the basal turn and distorted in the middle turn. In summary, our results demonstrate that TNF-?-mutant mice exhibit early hearing loss, especially at higher frequencies, and that loss or malformation of the stereocilia of outer hair cells appears to be a contributing factor. PMID:23996384

Oishi, Naoki; Chen, Jun; Zheng, Hong-Wei; Hill, Kayla; Schacht, Jochen; Sha, Su-Hua

2013-12-01

307

Hearing Loss Associated with Retinitis Pigmentosa. Short Reports.  

Science.gov (United States)

The article describes a variation of Usher's Syndrome, a genetic condition characterized by visual and auditory impairments, in which moderate, postlingual, and sometimes progressive hearing impairments may go undetected. Identification guidelines are offered. (Author/CL)

Karp, Adrienne

1985-01-01

308

The progression of hearing loss in the early stages of sudden deafness.  

Science.gov (United States)

The pathogenesis of sudden deafness is still not known. Therefore, to clarify its pathophysiology, it is important to know whether the progression of hearing loss occurs in the early stage of sudden deafness. The subjects were 11 patients with sudden deafness showing the progression of hearing loss by pure tone audiometry after the onset of the initial attack of hearing loss. The progression of hearing loss was mostly observed within 4-7 days after the onset of the initial attack. Average hearing loss in initial audiometry was severe and the recovery was poor in the majority of cases. An exploratory tympanotomy was performed in five cases and revealed one case of perilymphatic leak from the round window and another case of suspected round-window membrane rupture. As far as the causes of the progression of hearing loss in the early stage of sudden deafness are concerned, the following could be considered (1) aggravation of viral labyrinthitis, (2) aggravation of the vascular lesion of the inner ear, and (3) rupture of the membranous labyrinth of window(s). PMID:6626027

Kanzaki, J; O-Uchi, T

1983-01-01

309

Asymmetry in noise-induced hearing loss: evaluation of two competing theories.  

Science.gov (United States)

Competing theories exist about why asymmetry is observed in noise-induced hearing loss (NIHL). We evaluated these theories using a cohort of young workers studied over 16 years. The study aim was to describe and evaluate patterns of hearing loss and asymmetry by gender, agricultural exposure and gunfire exposure. This was a secondary analysis of data collected from young adults during follow-up of a randomized controlled trial. This follow-up study evaluated long-term effects of a hearing conservation intervention for rural students. The sample consisted of 392 of 690 participants from the original trial. In total, 355 young adults (aged 29-33 years) completed baseline and follow-up noise exposure surveys and clinical audiometric examinations. Data are displayed graphically as thresholds by frequency and ear and degree of asymmetry between ears (left minus right). In the primary group comparisons, low and high frequency averages and mean high frequency asymmetry were analyzed using mixed linear models. At frequencies >2000 Hz, men showed more hearing loss, with greater asymmetry and a different asymmetry pattern, than women. For men with documented hearing loss, there was a trend toward increasing asymmetry with increasing levels of hearing loss. Asymmetry at high frequencies varied substantially by level of shooting exposure. While "head shadowing" is accepted as the primary explanation for asymmetric hearing loss in the audiologic and related public health literature, our findings are more consistent with physiological differences as the primary cause of asymmetric hearing loss, with greater susceptibility to NIHL in the left ear of men. PMID:24804714

Berg, Richard L; Pickett, William; Linneman, James G; Wood, Douglas J; Marlenga, Barbara

2014-01-01

310

TBC1D24 Mutation Causes Autosomal-Dominant Nonsyndromic Hearing Loss.  

Science.gov (United States)

Hereditary hearing loss is extremely heterogeneous. Over 70 genes have been identified to date, and with the advent of massively parallel sequencing, the pace of novel gene discovery has accelerated. In a family segregating progressive autosomal-dominant nonsyndromic hearing loss (NSHL), we used OtoSCOPE® to exclude mutations in known deafness genes and then performed segregation mapping and whole-exome sequencing to identify a unique variant, p.Ser178Leu, in TBC1D24 that segregates with the hearing loss phenotype. TBC1D24 encodes a GTPase-activating protein expressed in the cochlea. Ser178 is highly conserved across vertebrates and its change is predicted to be damaging. Other variants in TBC1D24 have been associated with a panoply of clinical symptoms including autosomal recessive NSHL, syndromic hearing impairment associated with onychodystrophy, osteodystrophy, mental retardation, and seizures (DOORS syndrome), and a wide range of epileptic disorders. PMID:24729539

Azaiez, Hela; Booth, Kevin T; Bu, Fengxiao; Huygen, Patrick; Shibata, Seiji B; Shearer, A Eliot; Kolbe, Diana; Meyer, Nicole; Black-Ziegelbein, E Ann; Smith, Richard J H

2014-07-01

311

Acute sensorineural hearing loss and vertigo in a young adult with congenital plasminogen disorder.  

Science.gov (United States)

A 19-year-old Japanese man exhibiting acute right sensorineural hearing loss and vertigo was referred to the Jichi Medical School Hospital in June 1994. Although he had no history of recurrent thrombosis and no family history of thrombosis, he had undergone reconstruction of a right foot joint fracture 4 months earlier. Screening studies for plasminogen activity demonstrated 10% of normal plasminogen activity and his plasminogen was diagnosed as "plasminogen Tochigi" by the gene analysis using restriction enzyme Fnu4HI. The patient's hearing returned to normal with administration of heparin, and he was prescribed warfarin for the prevention of thrombosis until October 1995. There was no recurrence of hearing loss during seven years of follow-up. The cause of this patient's hearing loss is believed to be associated with consumption of the already low levels of plasminogen as a result of his surgery as well as congenital plasminogen disorder. PMID:16500059

Ishida, Takashi; Kitamura, Ken; Tanaka, Hidetaka; Ichimura, Keiichi; Mimuro, Jun; Madoiwa, Seiji; Sakata, Yoichi

2006-06-01

312

Recovery of sensorineural hearing loss following operative management of a posterior fossa arachnoid cyst. Case report.  

Science.gov (United States)

Arachnoid cysts are benign, intraarachnoid cysts filled with cerebrospinal fluid that are usually encountered in the middle cranial fossa. If present in the posterior fossa, they usually produce nonspecific signs and symptoms such as headaches, dizziness and vertigo. We report the rare presentation of a young girl with right-sided sensorineural hearing loss and tinnitus secondary to a right cerebellopontomedullary arachnoid cyst. The patient underwent a suboccipital retrosigmoid (retromastoid) craniectomy with fenestration of the arachnoid cyst. Subsequently, the patient experienced improvement in hearing with near-complete resolution of sensorineural hearing loss. To the authors' knowledge, postoperative near-complete resolution of hearing loss secondary to posterior fossa arachnoid cysts in a pediatric patient has not been previously reported. The authors also review the literature with respect to posterior fossa arachnoid cysts and discuss their clinical features, diagnosis, and management. PMID:19645544

Jayarao, Mayur; Devaiah, Anand K; Chin, Lawrence S

2009-08-01

313

Programa de prevenção de perdas auditivas em pescadores: perfil auditivo e ações educativas / Hearing loss prevention program in fishermen: hearing profile and educational actions  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese OBJETIVO: caracterizar o perfil de pescadores participantes de uma ação educativa desenvolvida como parte do Programa de Prevenção de Perdas Auditivas. MÉTODO: estudo seccional realizado com 52 pescadores industriais. Realizou-se ações educativas abordando temas pertinentes à audição, como funcionam [...] ento e cuidados. Após a ação, os participantes responderam a um questionário com questões referentes aos conceitos empregados na palestra e às queixas apresentadas, a seguir fizeram o exame de audiometria. RESULTADOS: a idade dos pescadores variou de 24 a 65 anos (média de 42,8 anos). 61,53% das audiometrias estavam alteradas, sendo que 96,8% dos pescadores com alterações auditivas tinham mais de 40 anos. No questionário respondido, 78,84% dos pescadores consideram que o ruído das embarcações é de forte intensidade; 17,31% referiam dificuldades auditivas; 30,77% com dificuldades em compreender fala e 46,15% com zumbido. 76,92% responderam que além da perda auditiva, o zumbido é um dos efeitos relacionados à exposição ao ruído. Todos estes resultados indicam a necessidade de intervenção preventiva individual e coletiva nesta população. O índice de perdas auditivas é um número que chama a atenção, porém, poucos sentem dificuldades auditivas. A ação educativa realizada foi o primeiro passo para a conscientização destes trabalhadores em relação à prevenção dos prejuízos que a exposição ao ruído pode causar à saúde. CONCLUSÕES: houve dependência significante entre o perfil auditivo e a idade dos pescadores, ou seja, a ocorrência de alterações auditivas é significativamente maior a partir de 40 anos de idade. Assim, os pescadores que apresentavam mais de 40 anos de idade tem 18,05 vezes mais alterações auditivas do que os com menos de 40 anos. Abstract in english PURPOSE: to characterize fishermen's profile, participating in an educational program developed as part of the Prevention of Hearing Loss. METHOD: a cross-sectional study conducted with 52 fishing industry. We carried out educational activities on topics relevant to hearing, such as, operation and c [...] are. After the program, the participants answered a questionnaire on the concepts used in the lecture and the presented complaints, and then they passed through the audiometric exam. RESULTS: the age of the participants varied from 24 to 65 year old (average 42.8 year old). 61.53% of audiometry exams were altered and 96.8% of fishermen with hearing loss were more than 40 year old. Answering the questionnaire: 78.84% of the fishermen feel the noise of boats is very intense, 17.31% reported hearing difficulties; 30.77% with difficulty to understanding speech and 46.15% with tinnitus. 76.92% answered that along with hearing loss, tinnitus is one of the effects related to exposure to noise. All these findings indicate the need for individual and collective preventive intervention in this population. The rate of hearing loss is a number that draws attention; however, few have hearing difficulty. The performed educational program was the first step to awareness of these workers regarding prevention of the damage that exposure to noise may come to cause to health. CONCLUSIONS: there was significant dependence between the auditory and age of the fishermen, in other words, the occurrence of hearing loss is significantly greater from 40 year old. Thus, the fishermen who were more than 40 year old had 18.05 times more hearing loss than those who are less than 40 year old.

Heupa, Adriana Betes; Gonçalves, Claudia Giglio de Oliveira; Albizu, Evelyn Joice; Iantas, Milena Raquel; Lacerda, Adriana Bender Moreira de; Lobato, Diolen Conceição Barros.

314

Programa de prevenção de perdas auditivas em pescadores: perfil auditivo e ações educativas Hearing loss prevention program in fishermen: hearing profile and educational actions  

Directory of Open Access Journals (Sweden)

Full Text Available OBJETIVO: caracterizar o perfil de pescadores participantes de uma ação educativa desenvolvida como parte do Programa de Prevenção de Perdas Auditivas. MÉTODO: estudo seccional realizado com 52 pescadores industriais. Realizou-se ações educativas abordando temas pertinentes à audição, como funcionamento e cuidados. Após a ação, os participantes responderam a um questionário com questões referentes aos conceitos empregados na palestra e às queixas apresentadas, a seguir fizeram o exame de audiometria. RESULTADOS: a idade dos pescadores variou de 24 a 65 anos (média de 42,8 anos. 61,53% das audiometrias estavam alteradas, sendo que 96,8% dos pescadores com alterações auditivas tinham mais de 40 anos. No questionário respondido, 78,84% dos pescadores consideram que o ruído das embarcações é de forte intensidade; 17,31% referiam dificuldades auditivas; 30,77% com dificuldades em compreender fala e 46,15% com zumbido. 76,92% responderam que além da perda auditiva, o zumbido é um dos efeitos relacionados à exposição ao ruído. Todos estes resultados indicam a necessidade de intervenção preventiva individual e coletiva nesta população. O índice de perdas auditivas é um número que chama a atenção, porém, poucos sentem dificuldades auditivas. A ação educativa realizada foi o primeiro passo para a conscientização destes trabalhadores em relação à prevenção dos prejuízos que a exposição ao ruído pode causar à saúde. CONCLUSÕES: houve dependência significante entre o perfil auditivo e a idade dos pescadores, ou seja, a ocorrência de alterações auditivas é significativamente maior a partir de 40 anos de idade. Assim, os pescadores que apresentavam mais de 40 anos de idade tem 18,05 vezes mais alterações auditivas do que os com menos de 40 anos.PURPOSE: to characterize fishermen's profile, participating in an educational program developed as part of the Prevention of Hearing Loss. METHOD: a cross-sectional study conducted with 52 fishing industry. We carried out educational activities on topics relevant to hearing, such as, operation and care. After the program, the participants answered a questionnaire on the concepts used in the lecture and the presented complaints, and then they passed through the audiometric exam. RESULTS: the age of the participants varied from 24 to 65 year old (average 42.8 year old. 61.53% of audiometry exams were altered and 96.8% of fishermen with hearing loss were more than 40 year old. Answering the questionnaire: 78.84% of the fishermen feel the noise of boats is very intense, 17.31% reported hearing difficulties; 30.77% with difficulty to understanding speech and 46.15% with tinnitus. 76.92% answered that along with hearing loss, tinnitus is one of the effects related to exposure to noise. All these findings indicate the need for individual and collective preventive intervention in this population. The rate of hearing loss is a number that draws attention; however, few have hearing difficulty. The performed educational program was the first step to awareness of these workers regarding prevention of the damage that exposure to noise may come to cause to health. CONCLUSIONS: there was significant dependence between the auditory and age of the fishermen, in other words, the occurrence of hearing loss is significantly greater from 40 year old. Thus, the fishermen who were more than 40 year old had 18.05 times more hearing loss than those who are less than 40 year old.

Adriana Betes Heupa

2011-12-01

315

Cochlea hair cell rescue after a noise-induced hearing loss using a low level laser therapy (LLLT)  

Science.gov (United States)

Aim: To see the effect of LLLT on noise-induced hearing loss. Methods: Eleven rats were exposed to noise (120 dB, 16 kHz, 6 h) and left ears were irradiated at 60J/cm2, 830 nm laser for 12 days. Right ears were control. Hearing levels were measured at frequencies of 4, 8, 12, 16, 32 kHz before noise exposure and after 12th irradiations. Results: The initial hearing levels were 26.5+/-4.7, 24.5+/-5.0, 24.0+/-5.2, 24.0+/-3.2, 24.5+/-5.5 dB SPL. After noise exposure, thresholds were 63.5+/-15.1, 64+/-16.8, 71.5+/-11.3, 73.5+/-15.6, 67.5+/-14.4 dB SPL in 4, 8, 12, 16, 32 kHz. After 12th irradiation, thresholds of treated ears recovered significantly 21+/-4.2, 20+/-3.5, 24+/-11.9, 24+/-12.9, 21+/-2.2 dB SPL and that of the untreated right ears measured 36.3+/-22.9, 45+/-15.8, 66.3+/-22.9, 50+/-16.8, 43.8+/-21.4 dB SPL. Conclusion: LLLT may promote recovery of hearing after noiseinduced hearing loss.

Rhee, Chung-Ku; Bahk, Chan Woong; Jung, Jae Yun; Ahn, Jin-Chul; Suh, Myung-Whan

2011-02-01

316

Hydrogen-Saturated Saline Protects Intensive Narrow Band Noise-Induced Hearing Loss in Guinea Pigs through an Antioxidant Effect  

Science.gov (United States)

The purpose of the current study was to evaluate hydrogen-saturated saline protecting intensive narrow band noise-induced hearing loss. Guinea pigs were divided into three groups: hydrogen-saturated saline; normal saline; and control. For saline administration, the guinea pigs were given daily abdominal injections (1 ml/100 g) 3 days before and 1 h before narrow band noise exposure (2.5–3.5 kHz 130 dB SPL, 1 h). The guinea pigs in the control group received no treatment. The hearing function was assessed by the auditory brainstem response (ABR) and distortion product otoacoustic emission (DPOAE) recording. The changes of free radicals in the cochlea before noise exposure, and immediately and 7 days after noise exposure were also examined. By Scanning electron microscopy and succinate dehydrogenase staining, we found that pre-treatment with hydrogen-saturated saline significantly reduced noise-induced hair cell damage and hearing loss. We also found that the malondialdehyde, lipid peroxidation, and hydroxyl levels were significantly lower in the hydrogen-saturated saline group after noise trauma, indicating that hydrogen-saturated saline can decrease the amount of harmful free radicals caused by noise trauma. Our findings suggest that hydrogen-saturated saline is effective in preventing intensive narrow band noise-induced hearing loss through the antioxidant effect.

Chen, Liwei; Yu, Ning; Lu, Yan; Wu, Longjun; Chen, Daishi; Guo, Weiwei; Zhao, Lidong; Liu, Mingbo; Yang, Shiming; Sun, Xuejun; Zhai, Suoqiang

2014-01-01

317

Hydrogen-Saturated Saline Protects Intensive Narrow Band Noise-Induced Hearing Loss in Guinea Pigs through an Antioxidant Effect.  

Science.gov (United States)

The purpose of the current study was to evaluate hydrogen-saturated saline protecting intensive narrow band noise-induced hearing loss. Guinea pigs were divided into three groups: hydrogen-saturated saline; normal saline; and control. For saline administration, the guinea pigs were given daily abdominal injections (1 ml/100 g) 3 days before and 1 h before narrow band noise exposure (2.5-3.5 kHz 130 dB SPL, 1 h). The guinea pigs in the control group received no treatment. The hearing function was assessed by the auditory brainstem response (ABR) and distortion product otoacoustic emission (DPOAE) recording. The changes of free radicals in the cochlea before noise exposure, and immediately and 7 days after noise exposure were also examined. By Scanning electron microscopy and succinate dehydrogenase staining, we found that pre-treatment with hydrogen-saturated saline significantly reduced noise-induced hair cell damage and hearing loss. We also found that the malondialdehyde, lipid peroxidation, and hydroxyl levels were significantly lower in the hydrogen-saturated saline group after noise trauma, indicating that hydrogen-saturated saline can decrease the amount of harmful free radicals caused by noise trauma. Our findings suggest that hydrogen-saturated saline is effective in preventing intensive narrow band noise-induced hearing loss through the antioxidant effect. PMID:24945316

Chen, Liwei; Yu, Ning; Lu, Yan; Wu, Longjun; Chen, Daishi; Guo, Weiwei; Zhao, Lidong; Liu, Mingbo; Yang, Shiming; Sun, Xuejun; Zhai, Suoqiang

2014-01-01

318

Medical surveillance of occupational Noise Induced Hearing Loss (NIHL) at RAPS hospital  

International Nuclear Information System (INIS)

Full text: One of the most challenging roles of a Certifying Surgeon is to act as catalyst for change. This paper is a presentation of the impact of such an effort. Noise is the insidious of all industrial pollutants, involving every industry and causing severe hearing loss. Exposure to excessive noise is the major avoidable cause of permanent hearing impairment. Noise - induced hearing loss (NIHL) is bilateral and symmetrical, usually affecting the higher frequencies 3 k, 4 k or 6 kHz ) and then spreading to the lower frequencies (0.5 k,1 k or 2 kHz). The major health effects are lack of concentration, irritation, fatigue, headache, sleep disturbances etc. Hearing protectors should be used when engineering controls and work practices are not feasible for reducing noise exposure to safe levels. Ear muffs, ear plugs and ear canal caps are the main types of hearing protectors. Awareness should be created among workers about the harmful effects of noise on hearing and other body systems by implementing compulsory education noise conservation programmes. The practice followed at RAPS Hospital for medical surveillance of Occupational Noise Induced Hearing Loss is being briefed

2009-01-01

319

Genetic and audiologic study in elderly with sensorineural hearing loss / Estudo genético e audiológico em idosos com perda auditiva sensorioneural  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in portuguese OBJETIVO: Este estudo teve como objetivo correlacionar prováveis fatores predisponentes para a perda auditiva sensorioneural em idosos, investigando as características audiológicas e a frequência de mutações em genes considerados responsáveis por perda auditiva não-sindrômica. MÉTODOS: Sessenta idos [...] os foram separados em dois grupos: Grupo de Caso, composto por 30 indivíduos, 21 do gênero feminino e nove do gênero masculino, com 60 anos ou mais, apresentando diagnóstico de perda auditiva sensorioneural, e o Grupo Controle, composto por 30 idosos pareados com o grupo experimental por idade e gênero, apresentando audição normal. Os pacientes foram submetidos à anamnese e audiometria tonal liminar nas frequências de 250, 500, 1000, 2000, 3000, 4000 e 6000 Hz. Amostras de sangue foram coletadas de cada paciente para análise de mutações em genes nucleares e mitocondriais relacionados à perda auditiva sensorioneural não sindrômica. RESULTADOS: Houve uma maior tendência à exposição a ruído e consumo de bebidas alcoólicas no Grupo de Caso. Os sintomas estatisticamente significativos entre os grupos foram zumbido e dificuldade para ouvir em diversas situações como: ambiente silencioso, telefone, televisão, localização sonora e na igreja. Todos os indivíduos do Grupo de Caso apresentaram perda auditiva sensorioneural bilateral. A simetria e progressão da deficiência auditiva também foram estatisticamente significativas entre os grupos. Não foram identificadas mutações genéticas. CONCLUSÃO: Os sintomas mais relatados foram zumbido e dificuldades de comunicação. As características audiológicas predominantes foram perda auditiva sensorioneural, bilateral, simétrica e progressiva. Não foi evidenciada relação entre perda auditiva sensorioneural em idosos e genes considerados responsáveis por perda auditiva não sindrômica, pois não foram encontradas mutações genéticas neste estudo. Abstract in english PURPOSE: This study aimed to correlate probable predisposing factors for sensorineural hearing loss in elderly by investigating the audiologic characteristics and frequency of mutations in genes considered responsible for non-syndromic hearing loss. METHODS: Sixty elderly patients were separated int [...] o two groups: the Case Group, composed of 30 individuals, 21 females and nine males, all 60 years old or older and presenting diagnoses of sensorineural hearing loss, and the Control Group, composed of 30 elderly individuals matched to the experimental group by age and gender, presenting normal hearing. The patients underwent anamnesis and pure tone audiometry in frequencies of 250, 500, 1000, 2000, 3000, 4000 and 6000 Hz. Blood samples were collected from each patient for analysis of mutations in nuclear and mitochondrial genes related to non-syndromic sensorineural hearing loss. RESULTS: It was observed a greater tendency to noise exposure and consumption of alcohol in the Case Group. The statistically significant symptoms between the groups were tinnitus and hearing difficulty in several situations as: silent environment, telephone, television, sound location and in church. All the individuals of Case Group presented sensorineural and bilateral hearing loss. The symmetry and progression of the hearing impairment were also statistically significant between the groups. No genetic mutations were identified. CONCLUSION: The most reported symptoms were communication difficulties and tinnitus. The predominant auditory characteristics included sensorineural, bilateral, progressive and symmetrical hearing loss. It was not evidenced a relationship between sensorineural hearing loss in elderly and genes considered responsible for non-syndromic hearing loss as no genetic mutation was found in this study.

Kelly, Martins; Marília, Fontenele; Silva, Câmara; Edi Lúcia, Sartorato.

320

Technology of formation of vertical stability bodies of children aged 7 10 years of hearing loss  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Purpose the development of technology forming the vertical stability of the body of primary school children with impaired hearing. We study the main directions, methods and techniques used in the process of physical education primary school children with impaired hearing. There was a significant backlog of children in this nosology in the development of the equilibrium function. Highlighted the principles of technology forming the vertical stability of hearing children. The technology include...

Storozhik A.I.

2013-01-01

 
 
 
 
321

Relative Contributions of Radiation and Cisplatin-Based Chemotherapy to Sensorineural Hearing Loss in Head-and-Neck Cancer Patients  

International Nuclear Information System (INIS)

Purpose: To investigate the risk of sensorineural hearing loss (SNHL) in patients with head-and-neck cancer and treated with radiation therapy (RT) or concomitant cisplatin-based chemoradiation, the relationship among SNHL and radiation dose to the cochlea, the use of two common cisplatin dose regimens. Methods and Materials: A total of 62 head-and-neck cancer patients treated with curative intent were included in this prospective study. Of the patients, 21 received RT alone, 27 received 40 mg/m2 weekly cisplatin, 13 received 100 mg/m2 every 3 weeks during RT, and 1 received RT with weekly epidermal growth factor receptor inhibitor antibody. The effect of chemotherapy and RT dose on hearing was determined using a model that accounted for the age and variability between each ear for each patient. Results: We constructed a model to predict dose-dependent hearing loss for RT or cisplatin-based chemotherapy either alone or in combination. For patients only receiving RT, no significant hearing loss was found at doses to the cochlea of less than 40 Gy. Patients receiving 100 mg/m2 or 40 mg/m2 of cisplatin chemotherapy had an estimated +21.5 dB and +9.5 dB hearing loss at 8,000 Hz with low radiation doses (10 Gy), which rose to +38.4 dB and +18.9 dB for high radiation doses (40 Gy). Conclusions: Use of RT alone with doses of less than 40 Gy did not result in clinically significant hearing loss. High-frequency SNHL was profoundly damaged in patients who received concomitant cisplatin when doses of 100 mg/m2 were used. The threshold cochlear dose for hearing loss with cisplatin-based chemotherapy and RT was predicted to be 10 Gy. The inner ear radiation dose constraints and cisplatin dose intensity should be considered in the treatment of advanced head-and-neck cancer

2009-03-01

322

Report on hearing loss in oncology / Classificações das perdas auditivas em Oncologia  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in portuguese A cisplatina é um antineoplásico muito utilizado no tratamento de diferentes neoplasias, porém quando utilizada em doses acima de 360mg/m² pode causar ototoxicidade. Esta produz lesões cocleares que resultam em perda auditiva. Existem critérios que visam identificar e quantificar as perdas auditivas [...] . OBJETIVO: Descrever as características das classificações e identificar implicações e aplicações de cada uma, dentro das necessidades do acompanhamento ao paciente oncológico. MATERIAL E MÉTODO: Avaliamos 31 pacientes pré e pós-tratamento quimioterápico. Classificamos as perdas auditivas de acordo com os critérios e verificamos a sensibilidade e especificidade de cada um. RESULTADO: Houve grande variabilidade na detecção das alterações auditivas (de 29% a 61%). Somente 4 dos 31 indivíduos com alterações auditivas no exame pós-tratamento foram identificados por todos os critérios. Por vezes o indivíduo portador de perda auditiva era classificado com normal por algum critério. Dos 31 indivíduos, 18 apresentaram PTA normal no exame pós-tratamento. CONCLUSÃO: Nenhum dos critérios considera a queixa do paciente. Os critérios descritos mostraram inadequações para descrever as alterações auditivas encontradas, fazendo-se necessária a descrição de informações adicionais, para que o médico compreendesse a natureza da perda auditiva. É importante o refinamento desses instrumentos para melhor compreensão e tratamento dos pacientes oncológicos, assim como de sua qualidade de vida. Abstract in english Cisplatin is used frequently as an antineoplastic drug in the treatment of many different cancers. However, when used in doses over 360mg/m², ototoxicity may ensue, resulting in loss of hearing. Criteria for identifying and quantifying hearing loss have been devised. AIM: To describe the features of [...] different hearing loss classification systems and to identify their implications and use in oncologic patients. METHOD: Hearing loss was classified in 31 patients before and after chemotherapy, according to different criteria, assessing the sensitivity and specificity of each classification system. RESULTS: Hearing loss results were highly variable (ranging from 29% to 61%). Only 4 of 31 subjects with post-therapy hearing loss were identified by all the methods. A few subjects with hearing loss were classified as normal hearing in some of the criteria. A normal PTA was found in 18 of 31 subjects in the post-treatment evaluation. CONCLUSION: None of the criteria assesses the complaints of patients. The criteria described in this study were inadequate to identify hearing loss following chemotherapy, requiring additional information for physicians to better understand the hearing losses and their implications for the quality of life of patients.

Schultz, Christiane; Goffi-Gomez, Maria Valéria Schmidt; Liberman, Patrícia Helena Pecora; Carvalho, André Lopes.

323

Report on hearing loss in oncology Classificações das perdas auditivas em Oncologia  

Directory of Open Access Journals (Sweden)

Full Text Available Cisplatin is used frequently as an antineoplastic drug in the treatment of many different cancers. However, when used in doses over 360mg/m², ototoxicity may ensue, resulting in loss of hearing. Criteria for identifying and quantifying hearing loss have been devised. AIM: To describe the features of different hearing loss classification systems and to identify their implications and use in oncologic patients. METHOD: Hearing loss was classified in 31 patients before and after chemotherapy, according to different criteria, assessing the sensitivity and specificity of each classification system. RESULTS: Hearing loss results were highly variable (ranging from 29% to 61%. Only 4 of 31 subjects with post-therapy hearing loss were identified by all the methods. A few subjects with hearing loss were classified as normal hearing in some of the criteria. A normal PTA was found in 18 of 31 subjects in the post-treatment evaluation. CONCLUSION: None of the criteria assesses the complaints of patients. The criteria described in this study were inadequate to identify hearing loss following chemotherapy, requiring additional information for physicians to better understand the hearing losses and their implications for the quality of life of patients.A cisplatina é um antineoplásico muito utilizado no tratamento de diferentes neoplasias, porém quando utilizada em doses acima de 360mg/m² pode causar ototoxicidade. Esta produz lesões cocleares que resultam em perda auditiva. Existem critérios que visam identificar e quantificar as perdas auditivas. OBJETIVO: Descrever as características das classificações e identificar implicações e aplicações de cada uma, dentro das necessidades do acompanhamento ao paciente oncológico. MATERIAL E MÉTODO: Avaliamos 31 pacientes pré e pós-tratamento quimioterápico. Classificamos as perdas auditivas de acordo com os critérios e verificamos a sensibilidade e especificidade de cada um. RESULTADO: Houve grande variabilidade na detecção das alterações auditivas (de 29% a 61%. Somente 4 dos 31 indivíduos com alterações auditivas no exame pós-tratamento foram identificados por todos os critérios. Por vezes o indivíduo portador de perda auditiva era classificado com normal por algum critério. Dos 31 indivíduos, 18 apresentaram PTA normal no exame pós-tratamento. CONCLUSÃO: Nenhum dos critérios considera a queixa do paciente. Os critérios descritos mostraram inadequações para descrever as alterações auditivas encontradas, fazendo-se necessária a descrição de informações adicionais, para que o médico compreendesse a natureza da perda auditiva. É importante o refinamento desses instrumentos para melhor compreensão e tratamento dos pacientes oncológicos, assim como de sua qualidade de vida.

Christiane Schultz

2009-10-01

324

Protecting Your Hearing  

Medline Plus

Full Text Available ... There are two general types of hearing loss. Conductive hearing loss occurs when sound waves cannot reach ... eardrum. Medical or surgical treatment can usually restore conductive hearing loss. Sensorineural hearing loss occurs when there ...

325

Effects of fundamental frequency and vocal-tract length cues on sentence segregation by listeners with hearing loss  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The purpose was to determine the effect of hearing loss on the ability to separate competing talkers using talker differences in fundamental frequency (F0) and apparent vocal-tract length (VTL). Performance of 13 adults with hearing loss and 6 adults with normal hearing was measured using the Coordinate Response Measure. For listeners with hearing loss, the speech was amplified and filtered according to the NAL-RP hearing aid prescription. Target-to-competition ratios varied from 0 to 9 dB. T...

Mackersie, Carol L.; Dewey, James; Guthrie, Lesli A.

2011-01-01

326

Relationships Between Speech Perception Abilities and Language Skills in Young Children with Hearing Loss  

Science.gov (United States)

Objective of the study The primary goal of this study was to examine relationships between scores obtained from measures of speech perception, standardized language, and spontaneous language samples in a group of young children with hearing loss (HL). Subjects and Methods Eighteen children with hearing loss (mean age = 4.3 years; range 2.4 – 6.3 years) and their mothers participated in this study. Speech perception was measured using the On-Line Imitative Test of Speech Pattern Contrast Perception (OLIMSPAC). Standardized language scores were obtained using the Reynell Developmental Language Scales-III. Number of word tokens, word types, and mean length of utterance (MLU) were extracted from the children’s spontaneous language samples. Results Only one significant positive association emerged between OLIMSPAC and standardized language scores. In contrast, strong positive associations emerged between OLIMSPAC and all measures derived from children’s spontaneous language samples (ranging from .77 to .90). Conclusions Assessment of speech perception, in combination with formal and informal language measures provides a more complete profile of the communication skills of young children with HL than each of these tests administered in isolation. Guidelines are offered for professionals who evaluate the communication abilities of young children with HL.

DesJardin, Jean L.; Martinez, Amy S.; Ambrose, Sophie E.; Eisenberg, Laurie S.

2011-01-01

327

Depression, Anxiety and Stress Scale in patients with tinnitus and hearing loss.  

Science.gov (United States)

The study was proposed to evaluate co-morbid depression, anxiety and stress associated with tinnitus patients. The study was done on 196 subjects: 100 patients suffering from subjective tinnitus associated with hearing loss (tinnitus group), 45 patients suffering from hearing loss only (hearing loss group) and 50 healthy subjects not suffering from tinnitus or hearing loss (control group); the age ranges from 20 to 60 years old. The studied sample was subjected to full ear, nose and throat examinations and audiological evaluation. Depression, Anxiety and Stress Scale (DASS) was developed by Levibond H and Levibond F to assess three self-report scales designed to measure the negative emotional status of depression, anxiety and stress. All patients and control group were evaluated by DASS. (1) Depression: males were affected more than females. All patients over 60 years were affected by depression. The duration of tinnitus seems correlating with the severity of depression. Only 2 patients (4.3 %) of the hearing loss group suffer from depression. (2) Anxiety: 90 % of males suffer from anxiety as compared to 83.3 % females. The age group 20-29 years old suffers more than other age groups. Only 4 patients (8.7 %) of hearing loss group suffer from anxiety. (3) Stress: females seem to be affected by the stress (76.7 %) more than males (67.5). Patients in age group 30-39 suffer the most from the disease. There is a direct correlation between duration of tinnitus and severity of stress. No one of the hearing loss group suffers from stress. In conclusion, depression, anxiety and stress should be taken into consideration in the treatment of patients suffering from tinnitus. PMID:24071860

Gomaa, Mohammed Abdel Motaal; Elmagd, Manal Hassan Abo; Elbadry, Mohammed Mohammed; Kader, Rafeek Mohammed Abdel

2014-08-01

328

Perception of across-frequency asynchrony by listeners with cochlear hearing loss.  

Science.gov (United States)

Cochlear hearing loss is often associated with broader tuning of the cochlear filters. Cochlear response latencies are dependent on the filter bandwidths, so hearing loss may affect the relationship between latencies across different characteristic frequencies. This prediction was tested by investigating the perception of synchrony between two tones exciting different regions of the cochlea in listeners with hearing loss. Subjective judgments of synchrony were compared with thresholds for asynchrony discrimination in a three-alternative forced-choice task. In contrast to earlier data from normal-hearing (NH) listeners, the synchronous-response functions obtained from the hearing-impaired (HI) listeners differed in patterns of symmetry and often had a very low peak (i.e., maximum proportion of "synchronous" responses). Also in contrast to data from NH listeners, the quantitative and qualitative correspondence between the data from the subjective and the forced-choice tasks was often poor. The results do not provide strong evidence for the influence of changes in cochlear mechanics on the perception of synchrony in HI listeners, and it remains possible that age, independent of hearing loss, plays an important role in temporal synchrony and asynchrony perception. PMID:23612740

Wojtczak, Magdalena; Beim, Jordan A; Micheyl, Christophe; Oxenham, Andrew J

2013-08-01

329

A frameshift mutation in GRXCR2 causes recessively inherited hearing loss.  

Science.gov (United States)

More than 360 million humans are affected with some degree of hearing loss, either early or later in life. A genetic cause for the disorder is present in a majority of the cases. We mapped a locus (DFNB101) for hearing loss in humans to chromosome 5q in a consanguineous Pakistani family. Exome sequencing revealed an insertion mutation in GRXCR2 as the cause of moderate-to-severe and likely progressive hearing loss in the affected individuals of the family. The frameshift mutation is predicted to affect a conserved, cysteine-rich region of GRXCR2, and to result in an abnormal extension of the C-terminus. Functional studies by cell transfections demonstrated that the mutant protein is unstable and mislocalized relative to wild-type GRXCR2, consistent with a loss-of-function mutation. Targeted disruption of Grxcr2 is concurrently reported to cause hearing loss in mice. The structural abnormalities in this animal model suggest a role for GRXCR2 in the development of stereocilia bundles, specialized structures on the apical surface of sensory cells in the cochlea that are critical for sound detection. Our results indicate that GRXCR2 should be considered in differential genetic diagnosis for individuals with early onset, moderate-to-severe and progressive hearing loss. PMID:24619944

Imtiaz, Ayesha; Kohrman, David C; Naz, Sadaf

2014-05-01

330

Mommy, Speak Clearly: Induced Hearing Loss Shapes Vowel Hyperarticulation  

Science.gov (United States)

Talkers hyperarticulate vowels when communicating with listeners that require increased speech intelligibility. Vowel hyperarticulation is said to be motivated by knowledge of the listener's linguistic needs because it typically occurs in speech to infants, foreigners and hearing-impaired listeners, but not to non-verbal pets. However, the degree…

Lam, Christa; Kitamura, Christine

2012-01-01

331

Management and motivational factors in the control of noise induced hearing loss (NIHL).  

Science.gov (United States)

This paper describes a study investigating attitudes to noise as an occupational hazard. The objectives of the study were to understand the individual and organizational factors which affect attitudes towards noise induced hearing loss (NIHL) and to relate these to the standards of hearing conservation achieved in industry as demonstrated by compliance with the Noise at Work Regulations. The study comprised a survey of 48 organizations across Britain, and a more detailed examination of 10 of these as case studies. Methods used included desk research, audits of hearing conservation programmes, questionnaires and interviews. Whilst there is widespread acceptance that industrial noise is a hazard, it is one that is frequently taken for granted, and measures to deal with it are often inadequate. Most organizations place the onus on the workforce to protect their own hearing through the use of personal hearing protectors. Workers reactions to noise tended however to be passive and much of the time neither managers nor the workforce are concious of the noise hazard. This is the case even where some managers are committed to good industrial housekeeping and accident prevention. As effective hearing conservation programme requires three management attributes: leadership from senior management, the ability of middle management (particularly in production and engineering) to put hearing conservation measures into practice, and specialist technical knowledge of noise and of the legislation. The study points to the need for more education and motivation of senior managers as the priority in improving standards of hearing conservation and noise control. PMID:7978989

Leinster, P; Baum, J; Tong, D; Whitehead, C

1994-10-01

332

Audição e percepção da perda auditiva em idosos / Hearing and perception of hearing loss in elderly people  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese OBJETIVO: Avaliar a audição e a percepção dos indivíduos idosos sobre a sua condição de audição. MÉTODOS: Foi desenvolvida uma pesquisa descritiva e exploratória, tendo como sujeitos 40 alunos, sendo 34 do sexo feminino e seis do sexo masculino, com idades variando entre 61 e 88 anos, de uma Univers [...] idade Aberta à Terceira Idade, localizada na cidade do Salvador, na Universidade do Estado da Bahia. Para avaliação dos sujeitos foi aplicado o Inventário Auditivo para Idosos - IAPI e realizado o exame audiométrico. A análise dos dados foi feita a partir das variáveis: sexo, faixa etária e pela computação das respostas dadas pelos indivíduos ao Inventário Auditivo para Idosos. RESULTADOS: Dos idosos 37,5% apresentaram audição normal e 62,5% perda auditiva, sendo 30% perda auditiva assimétrica e 32,5% simétrica. Dos 25 sujeitos com perda auditiva, apenas 3 (12%) tiveram percepção da mesma com um IAPI superior a dez pontos e 22 (88%) com uma pontuação inferior a dez. Quanto ao sexo, 8% de homens e 4% de mulheres tiveram uma pontuação superior a dez no IAPI; 16% dos indivíduos do sexo masculino e 72% do feminino apresentaram pontuação inferior a dez. Houve um predomínio da configuração audiométrica do tipo descendente em 88% dos sujeitos. CONCLUSÃO: A maioria dos sujeitos estudados era portadora de perda auditiva, sendo que, quanto maior a idade, maior esta deficiência. Proporcionalmente, a perda auditiva ocorreu mais em homens do que em mulheres, mas poucos percebem a sua existência. Abstract in english PURPOSE: To evaluate the hearing of elderly individuals and their perception regarding their hearing condition. METHODS: A descriptive and exploratory research was developed using as subjects 40 students from a University for the Third Age located in Salvador, Bahia (Brazil), being 34 female and 6 m [...] ale, with ages ranging from 61 to 88 years. The evaluation used the Hearing Handicap Inventory for Elderly - HHIE, and an audiometric assessment was carried out. Data analysis considered the following variables: gender, age and the answers computed in the HHIE. RESULTS: From the subjects, 37.5% had normal hearing and 62.5% presented hearing loss (30% asymmetric and 32.5% symmetric hearing loss). From the 25 subjects with hearing loss, only 3 (12%) were aware of it, according to the HHIE, scoring higher than ten points. In addition, 22 subjects (88%) had a score lower than ten. Regarding gender, 8% of the male subjects and 4% of the female subjects scored over ten at the HHIE; 16% of the male and 72% of the female scored under ten points. There was a predominance of the descendent audiometric configuration in 88% of the individuals. CONCLUSIONS: The majority of the subjects studied had hearing loss, which increased with age. Proportionally, hearing loss occurred mostly in men, although few of them were aware of its existence.

Sousa, Maria da Glória Canto de; Russo, Iêda Chaves Pacheco.

333

Ocorrência de perda auditiva induzida pelo ruído em carpinteiros Occurrence of noise induced hearing loss in carpenters  

Directory of Open Access Journals (Sweden)

Full Text Available OBJETIVO: investigar a ocorrência de perda auditiva induzida pelo ruído (PAIR em carpinteiros, caracterizando a perda auditiva por faixa etária, tempo de exposição total ao ruído e uso regular de protetores auditivos durante o tempo total de exposição. MÉTODO: estudo retrospectivo, descritivo, em uma população de 80 carpinteiros da construção civil, atendidos em uma clínica particular. Foram analisados 60 trabalhadores, conforme dados obtidos na anamnese e ficha do exame audiométrico. RESULTADOS: 49% dos trabalhadores apresentaram audição normal, sendo 58% com limiares auditivos normais bilateralmente e 35% com entalhe audiométrico em 3 kHz, 4 kHz e/ou 6 kHz. 44% apresentaram perfil audiométrico sugestivo de PAIR, destes 74% foram classificados como PAIR bilateral e 19% como PAIR unilateral. Houve diferença estatística significante entre os grupo PAIR e Normal em relação às variáveis idade (p=0,001, assim como o tempo total de exposição ao ruído ocupacional (p=0,002. CONCLUSÃO: quanto maior a idade e o tempo de profissão como carpinteiro, maior é a sua alteração auditiva, principalmente, devido à exposição ao ruído elevado durante a jornada de trabalho, sendo também constatado que as medidas de controle pelo uso do protetor são insuficientes para prevenir perdas auditivas. Portanto, sugerem-se medidas preventivas em saúde auditiva ativamente nessa população estudada, no ramo da construção civil.PURPOSE: to investigate the occurrence of noise induced hearing loss in carpenters, characterizing the hearing loss for age group, time of total exposure to noise and regular use of hearing protectors during the total exposure time. METHOD: retrospective and descriptive study in a population of 80 construction carpenters, attended at a private clinic. 60 workers were analyzed, as data on medical history and record of audiometric testing. RESULTS: 49% of the workers shoed normal hearing, being 58% with normal bilaterally hearing thresholds and 35% with audiometric notch in 3 kHz, 4 kHz and/or 6 kHz. 44% showed suggestive audiometric profile of NIHL, of these 74% were classified as bilateral NIHL and 19% as unilateral NIHL. There were significant differences between the NIHL group and normal to the age variables (p=0.001, as well as the total time of exposure to occupational noise (p=0,002. CONCLUSION: the greater the age and length of employment as a carpenter were, the greater their hearing loss, mainly due to exposure to loud noise during the working day, and we also noted that measures taken in order to control the use of the auricular protector are insufficient to prevent hearing loss. Therefore, we suggest active preventive measures in hearing health in this studied population, in the field of civil construction.

Victor Hygor Veríssimo Farias

2012-06-01

334

Acrylonitrile potentiates hearing loss and cochlear damage induced by moderate noise exposure in rats  

International Nuclear Information System (INIS)

The diversity of chemical and drugs that can potentiate noise-induced hearing loss (NIHL) has impeded efforts to predict such interactions. We have hypothesized that chemical contaminants that disrupt intrinsic antioxidant defenses hold significant risk for potentiating NIHL. If this is true, then acrylonitrile (ACN) would be expected to potentiate NIHL. ACN, one of the 50 most commonly used chemicals in the United States, is metabolized via two pathways that are likely to disrupt intrinsic reactive oxygen species (ROS) buffering systems: (1) it conjugates glutathione, depleting this important antioxidant rapidly; (2) a second pathway involves the formation of cyanide, which can inhibit superoxide dismutase. We hypothesized that moderate noise exposure, that does not produce permanent hearing loss by itself, could initiate oxidative stress and that ACN could render the inner ear more sensitive to noise by disrupting intrinsic antioxidant defenses. Temporary and persistent effects of ACN alone (50 mg/kg, sc 5 days), noise alone (95 or 97 dB octave band noise, 4 h/day for 5 days), or ACN in combination with noise were determined using distortion product otoacoustic emissions (DPOAEs) and compound action potential (CAP) amplitudes. Histopathological damage to hair cells resulting from these treatments was also investigated using surface preparations of the organ of Corti. Individually, neither ACN nor noise exposures caused any permanent hearing or hair cell loss; only a reversible temporary threshold shift was measured in noise-exposed animals. However, when given in combination, ACN and noise induced permanent threshold shifts (13-16 dB between 7 and 40 kHz) and a decrease in DPOAE amplitudes (up to 25 dB at 19 kHz), as well as significant outer hair cell (OHC) loss (up to 20% in the first row between 13 and 47 kHz). This investigation demonstrates that ACN can potentiate NIHL at noise levels that are realistic in terms of human exposure, and that the OHCs are the main target of toxicity. While the exact mechanism is unknown, the results are consistent with the hypothesis of ROS involvement in NIHL at moderate levels

2005-04-01

335

Hearing loss in Pompe disease revisited: results from a study of 24 children  

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Little information is available regarding the auditory function in Pompe patients. Hearing loss has been reported in classic infantile patients, but it is still unknown whether central nervous system involvement interferes with auditory function and whether enzyme replacement therapy can improve hearing. Auditory function has not been studied in children with milder forms of the disease. We analyzed repetitive auditory brainstem response measurements and pure tone audiometry in 24 children wi...

Capelle, C. I.; Goedegebure, A.; Homans, N. C.; Hoeve, L. J.; Reuser, A. J. J.; Ploeg, A. T.

2010-01-01

336

Noise-induced hearing loss: the family physician's role  

Energy Technology Data Exchange (ETDEWEB)

Noise is an environmental health problem that has not received sufficient attention. Physicians should become knowledgeable about the medical consequences of excessive noise, support legislation to reduce the problem and promote programs aimed at noise control and prevention of hearing loss. Questions about noise and hearing should be incorporated into the medical history, and pure-tone audiometry should be a part of periodic physical evaluations.

Dobie, R.A.

1987-12-01

337

Pitch, loudness and frequency selectivity in low-frequency hearing loss  

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Patients with Ménière's disease and cochlear hydrops show fluctuating low-frequency hearing loss (FLFHL). At present these changes are followed as patients' subjective reports and occasional measurements. Consecutive long-term measurements should provide more comprehensive information on the hearing fluctuations than the occasional audiogram used today and constitute an approach to quantify the fluctuations. Quantifications could potentially be used to define disease subgroups and ...

Bra?nnstro?m, Jonas

2009-01-01

338

Misdiagnosis of hearing loss due to ear canal collapse: A report of two cases  

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Collapse of the external auditory meatus during audiometry can lead to spuriously increased hearing thresholds : being obtained, particularly at high frequencies, and may simulate conditions such as noise-induced hearing loss, presbyacusis and retrocochlear pathology. Consequently, inappropriate investigations and management may be undertaken. Two patients with elevated thresholds secondary to ear canal collapse are described. The implications of initially failing to identify the true nature ...

Mahoney, C. F. O.; Luxon, L. M.

1996-01-01

339

Noise-induced hearing loss : prevalence, degree and impairment criteria in South African gold miners  

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Despite the preventability of noise-induced hearing loss (NIHL) a high prevalence is still reported in South African mines. The study aimed to describe the hearing of gold miners pertaining to the prevalence and degree of NIHL and effectiveness of current RSA impairment criteria to identify NIHL. The audiological data, collected between 2001 and 2008, of 57 714 mine workers were investigated in this retrospective cohort study. Data was accessed through the mine’s electronic database and exp...

2013-01-01

340

High-frequency tinnitus without hearing loss does not mean absence of deafferentation  

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A broad consensus within the neuroscience of tinnitus holds that this audiologic condition is triggered by central deafferentation, mostly due to cochlear damage. The absence of audiometrically detectable hearing loss however poses a challenge to this rather generalizing assumption. The aim of this study was therefore to scrutinize cochlear functioning in a sample of tinnitus subjects audiometrically matched to a normal hearing control group. Two tests were applied: the Threshold Equalizing N...

Weisz, Nathan; Hartmann, Thomas; Dohrmann, Katalin; Schlee, Winfried; Norena, Arnaud

2006-01-01

 
 
 
 
341

Prelude: noise-induced tinnitus and hearing loss in the military.  

Science.gov (United States)

Hearing is critical to the performance of military personnel and is integral to the rapid and accurate processing of speech information. Thus, noise-induced hearing loss (NIHL) represents a severe impairment that reduces military effectiveness, safety, and quality of life. With the high levels of noise to which military personnel are exposed and the limited protection afforded by hearing conservation programs, it should be no surprise that annual Veterans Affairs disability payments for tinnitus and hearing loss exceeded $1.2 billion for 2009 and continue to increase. Military personnel work in high-noise environments, yet the Department of Defense (DoD) cannot predict who is susceptible to noise-induced hearing loss and tinnitus. Of those exposed to noise, 80% may also suffer from chronic tinnitus. Despite its prevalence, there are no means to objectively measure the severity of tinnitus in those individuals. A fundamental understanding of the underlying mechanisms of tinnitus and its relation to noise-induced hearing loss is critical. Such an understanding may provide insight to who is at risk for each condition, allow aggressive hearing protection measures in those individuals most at risk, and create areas for treatment for those already suffering from the conditions. The current review will address the scope of the problems of NIHL and tinnitus for the military, discuss the noise environments in which military personnel operate, describe the hearing conservation measures currently in place, and the challenges those programs face. Some recent breakthroughs in NIHL research will be discussed along with some challenges and directions for future research on NIHL and tinnitus. PMID:22575206

Yankaskas, Kurt

2013-01-01

342

The More the Worse: the Grade of Noise-Induced Hearing Loss Associates with the Severity of Tinnitus  

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Tinnitus disturbs lives and negatively affects the quality of life of about 2% of the adult world population. Research has shown that the main cause of tinnitus is hearing loss. To analyze a possible association of the degree of hearing loss with the severity of tinnitus, we have performed a retrospective study using admission data on 531 patients suffering from chronic tinnitus. We have found that 83% of our tinnitus patients had a high frequency hearing loss corresponding to a noise-induced...

2010-01-01

343

A comprehensive introduction to the genetic basis of non-syndromic hearing loss in the Saudi Arabian population  

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Abstract Background Hearing loss is a clinically and genetically heterogeneous disorder. Mutations in the DFNB1 locus have been reported to be the most common cause of autosomal recessive non-syndromic hearing loss worldwide. Apart from DFNB1, many other loci and their underlying genes have also been identified and the basis of our study was to provide a comprehensive introduction to the delineation of the molecular basis of non-syndromic hearing loss in the...

2011-01-01

344

Autosomal Recessive and Sporadic Non Syndromic Hearing Loss and the Incidence of Cx26 Mutations in a Province of Iran  

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Despite the enormous heterogeneity of genetic hearing loss, mutations in the GJB2 (connexin 26) gene located on “DFNB1” locus (13q12) account for up to 50% of cases of autosomal recessive non-syndromic hearing loss (ARNSHL) in some populations. This study describes the analysis of 100 autosomal recessive and sporadic nonsyndromic hearing loss individuals from 79 families each having at least one deaf child in Chehar Mahal va Bakhtiari province in west of Iran. We have investigated the pre...

Hashemzadeh Chaleshtori, M.; Montazer Zohour, M.; Hoghooghi Rad, L.; Pour-jafari, H.; Dd, Farhud; Dolati, M.; Safa Chaleshtori, K.; Sasanfar, R.; Hosseinipour, A.; Andonian, L.; Tolouei, A.; Ghadami, M.; Ma, Patton

2006-01-01

345

Genetic aspects of the BOR syndrome--branchial fistulas, ear pits, hearing loss, and renal anomalies.  

Science.gov (United States)

A pedigree of branchio-oto-renal dysplasia (the BOR syndrome) is reported, including the documentation by serial audiometric studies of the onset and rapid progression of hearing loss in the twin sister of an affected child. The literature on this syndrome is analyzed to derive some figures for use in genetic counseling of such families. Branchio-oto-renal dysplasia is an autosomal dominant disorder in which affected individuals may have preauricular pits, lachrymal duct stenosis, hearing loss, branchial fistulas or cysts, structural defects of the outer, middle, and inner ear, and renal anomalies, which may range from mild hypoplasia to complete absence. Not all features of the syndrome are expressed in all carriers of the gene, but few carriers lack all the features, and the pits, branchial clefts, and hearing loss, are frequently expressed. Those offspring of affected persons who have pits or fistulas are likely (about 80%) to have hearing loss of varying degrees of severity. A minority of heterozygotes (about 7%) may have hearing loss without pits or fistulas. The risk of severe renal malformation is probably fairly low. Whether families that show dominant inheritance of pits, clefts, and deafness without renal anomalies represent variants of the BOR syndrome or a separate entity (the BO syndrome), is still not clear. At present, any individual with preauricular pits and branchial clefts deserves both otologic and renal investigation. PMID:263442

Fraser, F C; Ling, D; Clogg, D; Nogrady, B

1978-01-01

346

Literacy skills of Australian Indigenous school children with and without otitis media and hearing loss.  

Science.gov (United States)

This study examined the relationship between reading, spelling, and the presence of otitis media (OM) and co-occurring hearing loss (HL) in metropolitan Indigenous Australian children, and compared their reading and spelling outcomes with those of their non-Indigenous peers. OM and HL may hinder language development and phonological awareness skills, but there is little empirical evidence to link OM/HL and literacy in this population. Eighty-six Indigenous and non-Indigenous children attending pre-primary, year one and year two at primary schools in the Perth metropolitan area participated in the study. The ear health of the participants was screened by Telethon Speech and Hearing Centre EarBus in 2011/2012. Participants' reading and spelling skills were tested with culturally modified sub-tests of the Queensland University Inventory of Literacy. Of the 46 Indigenous children, 18 presented with at least one episode of OM and one episode of HL. Results indicated that Indigenous participants had significantly poorer non-word and real word reading and spelling skills than their non-Indigenous peers. There was no significant difference between the groups of Indigenous participants with OM and HL and those with normal ear health on either measure. This research provides evidence to suggest that Indigenous children have ongoing literacy development difficulties and discusses the possibility of OM as one of many impacting factors. PMID:24460058

Timms, Lydia; Williams, Cori; Stokes, Stephanie F; Kane, Robert

2014-06-01

347

Subchronic JP-8 jet fuel exposure enhances vulnerability to noise-induced hearing loss in rats.  

Science.gov (United States)

Both laboratory and epidemiological studies published over the past two decades have identified the risk of excess hearing loss when specific chemical contaminants are present along with noise. The objective of this study was to evaluate the potency of JP-8 jet fuel to enhance noise-induced hearing loss (NIHL) using inhalation exposure to fuel and simultaneous exposure to either continuous or intermittent noise exposure over a 4-wk exposure period using both male and female Fischer 344 rats. In the initial study, male (n?=?5) and female (n?=?5) rats received inhalation exposure to JP-8 fuel for 6 h/d, 5 d/wk for 4 wk at concentrations of 200, 750, or 1500 mg/m³. Parallel groups of rats also received nondamaging noise (constant octave band noise at 85 dB(lin)) in combination with the fuel, noise alone (75, 85, or 95 dB), or no exposure to fuel or noise. Significant concentration-related impairment of auditory function measured by distortion product otoacoustic emissions (DPOAE) and compound action potential (CAP) threshold was seen in rats exposed to combined JP-8 plus noise exposure when JP-8 levels of 1500 mg/m³ were presented with trends toward impairment seen with 750 mg/m³ JP-8?+?noise. JP-8 alone exerted no significant effect on auditory function. In addition, noise was able to disrupt the DPOAE and increase auditory thresholds only when noise exposure was at 95 dB. In a subsequent study, male (n?=?5 per group) and female (n?=?5 per group) rats received 1000 mg/m³ JP-8 for 6 h/d, 5 d/wk for 4 wk with and without exposure to 102 dB octave band noise that was present for 15 min out of each hour (total noise duration 90 min). Comparisons were made to rats receiving only noise, and thosereceiving no experimental treatment. Significant impairment of auditory thresholds especially for high-frequency tones was identified in the male rats receiving combined treatment. This study provides a basis for estimating excessive hearing loss under conditions of subchronic JP-8 jet fuel exposure. PMID:22409492

Fechter, L D; Fisher, J W; Chapman, G D; Mokashi, V P; Ortiz, P A; Reboulet, J E; Stubbs, J E; Lear, A M; McInturf, S M; Prues, S L; Gearhart, C A; Fulton, S; Mattie, D R

2012-01-01

348

Tinnitus-related dissociation between cortical and subcortical neural activity in humans with mild to moderate sensorineural hearing loss.  

Science.gov (United States)

Tinnitus is a phantom sound percept that is strongly associated with peripheral hearing loss. However, only a fraction of hearing-impaired subjects develops tinnitus. This may be based on differences in the function of the brain between those subjects that develop tinnitus and those that do not. In this study, cortical and sub-cortical sound-evoked brain responses in 34 hearing-impaired chronic tinnitus patients and 19 hearing level-matched controls were studied using 3-T functional magnetic resonance imaging (fMRI). Auditory stimuli were presented to either the left or the right ear at levels of 30-90 dB SPL. We extracted neural activation as a function of sound intensity in eight auditory regions (left and right auditory cortices, medial geniculate bodies, inferior colliculi and cochlear nuclei), the cerebellum and a cinguloparietal task-positive region. The activation correlated positively with the stimulus intensity, and negatively with the hearing threshold. We found no differences between both groups in terms of the magnitude and lateralization of the sound-evoked responses, except for the left medial geniculate body and right cochlear nucleus where activation levels were elevated in the tinnitus subjects. We observed significantly reduced functional connectivity between the inferior colliculi and the auditory cortices in tinnitus patients compared to controls. Our results indicate a failure of thalamic gating in the development of tinnitus. PMID:24631963

Boyen, Kris; de Kleine, Emile; van Dijk, Pim; Langers, Dave R M

2014-06-01

349

Auditory Screening in Infants for Early Detection of Permanent Hearing Loss in Northern Iran  

Science.gov (United States)

Background: Undiagnosed hearing loss can cause disorders in speech and language and delay in social and emotional development. Aim: This study aimed to screen for hearing loss in all newborns born in Babol city during 2009-2011. Subjects and Methods: Fifteen thousand one hundred and sixty-five newborns (49% [7430/15165] male and 51% [7735/15165] female) born during a 30-month period in Babol, underwent hearing screening by the otoacoustic emission (OAE) test at the age of 15 days. In infants referred at this stage, an auditory brainstem response (ABR) test was the next investigation. Data analyzed using Statistical Package for the Social Sciences software Version 16 (Chicago, IL, USA, 16) through descriptive statistic method. Results: In the first screening stage, 10.8% (1648/15165) cases were referred to the second stage for further investigation. 9.4% (154/1648) were lost to follow-up from among the referred cases despite continuous contact and education about the importance of the problem. Among the participants in the second stage, 6.2% (92/1494) were referred to the third stage and underwent ABR and OAE testing. 14.1% (13/92) were lost at this stage. Of the remaining participants, 34.2% (27/79) were diagnosed with a hearing loss. Therefore, the incidence of hearing loss in this study was 1.8/1,000 newborns. Conclusion: Given the prevalence of hearing loss in this study, implementation of a universal newborn hearing screening program is recommended.

Haghshenas, M; Zadeh, PY; Javadian, Y; Fard, HA; Delavari, K; Panjaki, HSA; Gorji, HAMH

2014-01-01

350

A Rapid Method for Simultaneous Screening of Multi-Gene Mutations Associated with Hearing Loss in the Korean Population  

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Hearing loss (HL) is a congenital disease with a high prevalence, and patients with hearing loss need early diagnosis for treatment and prevention. The GJB2, MT-RNR1, and SLC26A4 genes have been reported as common causative genes of hearing loss in the Korean population and some mutations of these genes are the most common mutations associated with hearing loss. Accordingly, we developed a method for the simultaneous detection of seven mutations (c.235delC of GJB2, c.439A>G, c.919-2A>G, c.114...

2013-01-01

351

What are the audiometric frequencies affected are the responsible for the hearing complaint in the hearing loss for ototoxicity after the oncological treatment?  

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Introduction: The neurosensory bilateral simetric hearing loss resulting of the oncological treatment is underestimated, because the patients has the hearing detection preserved, reporting complaints in determined situation, or the not comprehension of part of the message. Objective: Investigate which are the audiometric frequencies affected are the responsible by the presence of hearing complaints. Method: Prospective study evaluating 200 patients with cancer in the childhood out of the onco...

2012-01-01

352

The risk of noise-induced hearing loss in the Danish workforce  

DEFF Research Database (Denmark)

The causal association between occupational noise exposure and permanent hearing loss is well-documented and well-founded primary preventive approaches have been developed. However, documentation of the impact on the present prevalence of noise-induced hearing loss in the working population is limited. This study reports on the prevalence of noise-induced hearing loss in a population sample of 788 workers from 11 trades with expected high noise exposure levels and a reference group examined according to the same protocol. Full-shift A-weighted equivalent sound levels were recorded and pure tone audiometric examinations were conducted at the work sites in soundproof booths. Data were analyzed with multivariate regression techniques and adjusted for age, sex, ear disease, smoking and environmental noise exposure. An overall two-fold increased risk of hearing handicap (hearing threshold above 20 dB averaged across 2, 3 and 4 kHz for either ear) was observed in the noise exposed workers [odds ratio (OR) 1.99, 95%confidence interval (CI) 0.91-4.34]. Workers exposed for more than 20 years to an exposure level above 85 dB(A) had a three-fold increased risk (OR 3.05, 95% CI 1.33-6.99). Workers starting in noisy work during the last 10-15 years or workers below 30 years of age showed no increased risk of hearing handicap. This indicates that preventive measures enforced during the past 10-15 years to reduce noise exposure may have borne fruit. Systematic surveillance of noise and hearing levels in appropriate populations should still be included in an efficient hearing conservation program.

Rubak, Tine; Thrysøe, Samuel Alberg

2006-01-01

353

Recognition of accented English in quiet by younger normal-hearing listeners and older listeners with normal-hearing and hearing loss  

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This investigation examined the effects of listener age and hearing loss on recognition of accented speech. Speech materials were isolated English words and sentences that featured phonemes that are often mispronounced by non-native speakers of English whose first language is Spanish. These stimuli were recorded by a native speaker of English and two non-native speakers of English: one with a mild accent and one with a moderate accent. The stimuli were presented in quiet to younger and older ...

Gordon-salant, Sandra; Yeni-komshian, Grace H.; Fitzgibbons, Peter J.

2010-01-01

354

Academic engagement in students with a hearing loss in distance education.  

Science.gov (United States)

This investigation compared 267 students with a hearing loss and 178 students with no declared form of disability who were taking courses by distance learning in terms of their scores on an abbreviated version of the Academic Engagement Form. Students with a hearing loss obtained lower scores than students with no disability with regard to communication with other students, but some felt that communication was easier than in a traditional academic situation. Students who were postvocationally deaf had lower scores than students with no disability on learning from other students, but they obtained higher scores on student autonomy and student control. In general, the impact of a hearing loss on engagement in distance education is relatively slight. PMID:15304403

Richardson, John T E; Long, Gary L; Foster, Susan B

2004-01-01

355

X-linked hearing loss: two gene mutation examples provide generalizable implications for clinical care.  

Science.gov (United States)

PURPOSE To describe the inheritance patterns and auditory phenotype features of 3 Canadian families with mutations in 2 X-linked "deafness" genes (DFNX). METHOD Audiological, medical, and family histories were collected and family members interviewed to compare hearing thresholds and case histories between cases with mutations in SMPX versus POU3F4. RESULTS The family pedigrees reveal characteristic X-linked inheritance patterns. Phenotypic features associated with the SMPX (DFNX4) mutation include early onset in males with rapid progression from mild and flat to sloping sensorineural loss, with highly variable onset and hearing loss severity in females. In contrast, phenotypic features associated with the POU3F4 (DFNX2) mutation are characterized by an early onset, mixed hearing loss with fluctuation in males, and a normal hearing phenotype reported for females. CONCLUSIONS The study shows how this unique inheritance pattern and both gender and mutation-specific phenotype variations can alert audiologists to the presence of X-linked genetic etiologies in their clinical practice. By incorporating this knowledge into clinical decision making, audiologists can facilitate the early identification of X-linked hearing loss and contribute to the effective team management of affected families. PMID:24687041

Stanton, Susan G; Griffin, Anne; Stockley, Tracy L; Brown, Christine; Young, Terry-Lynn; Benteau, Tammy; Abdelfatah, Nelly

2014-06-01

356

OTOF mutation screening in Japanese severe to profound recessive hearing loss patients  

Science.gov (United States)

Background Auditory neuropathy spectrum disorder (ANSD) is a unique form of hearing loss that involves absence or severe abnormality of auditory brainstem response (ABR), but also the presence of otoacoustic emissions (OAEs). However, with age, the OAEs disappear, making it difficult to distinguish this condition from other nonsyndromic hearing loss. Therefore, the frequency of ANSD may be underestimated. The aim of this study was to determine what portion of nonsyndromic hearing loss is caused by mutations of OTOF, the major responsible gene for nonsyndromic ANSD. Methods We screened 160 unrelated Japanese with severe to profound recessive nonsyndromic hearing loss (ARNSHL) without GJB2 or SLC26A4 mutations, and 192 controls with normal hearing. Results We identified five pathogenic OTOF mutations (p.D398E, p.Y474X, p.N727S, p.R1856Q and p.R1939Q) and six novel, possibly pathogenic variants (p.D450E, p.W717X, p.S1368X, p.R1583H, p.V1778I, and p.E1803A). Conclusions The present study showed that OTOF mutations accounted for 3.2–7.3% of severe to profound ARNSHL patients in Japan. OTOF mutations are thus a frequent cause in the Japanese deafness population and mutation screening should be considered regardless of the presence/absence of OAEs.

2013-01-01

357

Relationship between styrene exposure and hearing loss: review of human studies.  

Science.gov (United States)

Styrene is an aromatic solvent belonging to the alkylbenzene family. Occupational exposure to styrene occurs mainly in the manufacturing of fiberglass-reinforced polyester products, e.g. reinforced plastics and composites. Since 1988, nine studies have been published on the relationship between occupational exposure to styrene and hearing loss. All studies were the cross-sectional epidemiological studies or clinical studies from occupational health clinics. A total of more than 1000 workers exposed to styrene, both with and without concurrent noise exposure, were examined using different outcome measures for hearing loss. Exposure assessment was usually based on styrene measurements in the breathing zone during several hours of one working day. Some of the studies employed also the biological monitoring of styrene exposure based on determination of its urinary metabolites. The current exposures to styrene varied between 2 and 35 ppm. In some studies, lifetime exposure was calculated using company records and questionnaire data. The current exposure to noise was estimated by noise dosimetry or standard noise measurements. Lifetime noise exposure was assessed using questionnaire data and occupational noise estimates. In many studies, noise-exposed groups were used as controls together with the unexposed workers. Of the nine studies, seven show some effects on the auditory system that were associated with styrene-alone exposure. These effects are examined using different outcome measures such as pure tone audiometry, high frequency hearing loss, and central hearing tests. In some studies, an increased risk for hearing loss was associated with exposure estimates. PMID:18165194

Johnson, Ann-Christin

2007-01-01

358

Efficacy of three drugs for protecting against gentamicin-induced hair cell and hearing losses  

Science.gov (United States)

BACKGROUND AND PURPOSE Exposure to an ototoxic level of an aminoglycoside can result in hearing loss. In this we study investigated the otoprotective efficacy of dexamethasone (DXM), melatonin (MLT) and tacrolimus (TCR) in gentamicin (GM)-treated animals and cultures. EXPERIMENTAL APPROACH Wistar rats were divided into controls (treated with saline); exposed to GM only (GM); and three GM-exposed groups treated with either DXM, MLT or TCR. Auditory function and cochlear surface preparations were studied. In vitro studies of oxidative stress, pro-inflammatory cytokine mRNA levels, the MAPK pathway and caspase-3 activation were performed in organ of Corti explants from 3-day-old rats. KEY RESULTS DXM, MLT and TCR decreased levels of reactive oxygen species in GM-exposed explants. The mRNA levels of TNF-?, IL-1? and TNF-receptor type 1 were significantly reduced in GM + DXM and GM + MLT groups. Phospho-p38 MAPK levels decreased in GM + MLT and GM + TCR groups, while JNK phosphorylation was reduced in GM + DXM and GM + MLT groups. Caspase-3 activation decreased in GM + DXM, GM + MLT and GM + TCR groups. These results were consistent with in vivo results. Local treatment of GM-exposed rat cochleae with either DXM, MLT or TCR preserved auditory function and prevented auditory hair cell loss. CONCLUSIONS AND IMPLICATIONS In organ of Corti explants, GM increased oxidative stress and initiated an inflammatory response that led to the activation of MAPKs and apoptosis of hair cells. The three compounds tested demonstrated otoprotective properties that could be beneficial in the treatment of ototoxicity-induced hearing loss.

Bas, E; Van De Water, TR; Gupta, C; Dinh, J; Vu, L; Martinez-Soriano, F; Lainez, JM; Marco, J

2012-01-01

359

P300 em sujeitos com perda auditiva / P300 in subjects with hearing loss  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese TEMA: as avaliações comportamentais e eletrofisiológicas contribuem para o entendimento do sistema auditivo e do processo de intervenção. OBJETIVO: estudar P300 em sujeitos com perda auditiva neurossensorial congênita, segundo as variáveis gênero, idade e grau da perda auditiva. MÉTODO: a presente i [...] nvestigação consiste em um estudo descritivo, transversal. Foram examinados 29 sujeitos, sendo 15 do gênero masculino e 14 do gênero feminino, com idade entre 11 a 42 anos. Os critérios de elegibilidade para composição da amostra foram: idade superior a 11 anos e inferior a 45 anos; ser portador de deficiência auditiva congênita severa ou profunda; não apresentar outro tipo de distúrbio; não apresentar perda auditiva central e/ou comprometimento condutivo. A primeira etapa caracterizou-se por avaliação comportamental auditiva e fisiológica que incluiu: audiometria tonal limiar (via aérea e via óssea), logoaudiometria - LDV e medidas do ganho funcional para os sujeitos que faziam uso de próteses auditivas, Imitanciometria: curva timpanométrica e pesquisa dos reflexos ipsi e contra-laterais, registro das emissões otoacústicas (EOA) - emissões otoacústicas transitórias (EOAT) e emissões otoacústicas por produto de distorção (EOAPD). A avaliação eletrofisiológica constituiu a quarta etapa do procedimento de coleta de dados e incluiu: potenciais auditivos evocados de tronco encefálico (PEATE) e de longa latência (P300). RESULTADOS: o P300 foi registrado em 17 sujeitos, com latência e amplitude média de 326,97ms e 3,76V, respectivamente. Apresentou diferenças significantes da latência em relação à idade (p Abstract in english BACKGROUND: behavioral and electrophysiological evaluations contribute to the understanding of the hearing system and to the intervention process. AIM: to investigate the occurrence of P300 in subjects with congenital severe to profound hearing loss, according to the variables of gender, age and hea [...] ring loss level. METHOD: the design of this research is a descriptive transversal study. Twenty-nine subjects, 15 male and 14 female, ranging in age from 11 to 42 years, were evaluated. Inclusion criteria were: to have at least 11 years of age and no more than 45 years; to have the diagnosis of congenital severe to profound sensorineural hearing loss; to have no other disorder; and absence of central hearing loss or any other auditory conductive disorder. The first stage consisted of an auditory behavioral and physiological evaluation, including: pure tone audiometry (air and bone conduction measures), speech audiometry, SDT (Speech Detection Threshold) and functional gain measures for the subjects using hearing aids, and immittance measures - tympanometry and acoustic reflexes thresholds; transient evoked otoacoustic emissions (TEOAE); distortion product otoacoustic emissions (DPOAE). The electrophysiological evaluation was the fourth stage of the study and included: auditory brainstem response (ABR) and late latency response (P300). RESULTS: P300 was obtained for 17 out of the 29 subjects. Mean latency and amplitude were 326.97 ms and 3.76 V, respectively. A statistical significant difference was observed for latency when considering the variable age (electrode CzA2 p

Ana Cláudia Mirândola Barbosa, Reis; Maria Cecília Martinelli, Iório.

360

Sensorineural hearing loss amplifies neural coding of envelope information in the central auditory system of chinchillas.  

Science.gov (United States)

People with sensorineural hearing loss often have substantial difficulty understanding speech under challenging listening conditions. Behavioral studies suggest that reduced sensitivity to the temporal structure of sound may be responsible, but underlying neurophysiological pathologies are incompletely understood. Here, we investigate the effects of noise-induced hearing loss on coding of envelope (ENV) structure in the central auditory system of anesthetized chinchillas. ENV coding was evaluated noninvasively using auditory evoked potentials recorded from the scalp surface in response to sinusoidally amplitude modulated tones with carrier frequencies of 1, 2, 4, and 8 kHz and a modulation frequency of 140 Hz. Stimuli were presented in quiet and in three levels of white background noise. The latency of scalp-recorded ENV responses was consistent with generation in the auditory midbrain. Hearing loss amplified neural coding of ENV at carrier frequencies of 2 kHz and above. This result may reflect enhanced ENV coding from the periphery and/or an increase in the gain of central auditory neurons. In contrast to expectations, hearing loss was not associated with a stronger adverse effect of increasing masker intensity on ENV coding. The exaggerated neural representation of ENV information shown here at the level of the auditory midbrain helps to explain previous findings of enhanced sensitivity to amplitude modulation in people with hearing loss under some conditions. Furthermore, amplified ENV coding may potentially contribute to speech perception problems in people with cochlear hearing loss by acting as a distraction from more salient acoustic cues, particularly in fluctuating backgrounds. PMID:24315815

Zhong, Ziwei; Henry, Kenneth S; Heinz, Michael G

2014-03-01

 
 
 
 
361

Copy number variants are a common cause of non-syndromic hearing loss  

Science.gov (United States)

Background Copy number variants (CNVs) are a well-recognized cause of genetic disease; however, methods for their identification are often gene-specific, excluded as ‘routine’ in screens of genetically heterogeneous disorders, and not implemented in most next-generation sequencing pipelines. For this reason, the contribution of CNVs to non-syndromic hearing loss (NSHL) is most likely under-recognized. We aimed to incorporate a method for CNV identification as part of our standard analysis pipeline and to determine the contribution of CNVs to genetic hearing loss. Methods We used targeted genomic enrichment and massively parallel sequencing to isolate and sequence all exons of all genes known to cause NSHL. We completed testing on 686 patients with hearing loss with no exclusions based on type of hearing loss or any other clinical features. For analysis we used an integrated method for detection of single nucleotide changes, indels and CNVs. CNVs were identified using a previously published method that utilizes median read-depth ratios and a sliding-window approach. Results Of 686 patients tested, 15.2% (104) carried at least one CNV within a known deafness gene. Of the 38.9% (267) of individuals for whom we were able to determine a genetic cause of hearing loss, a CNV was implicated in 18.7% (50). We identified CNVs in 16 different genes including 7 genes for which no CNVs have been previously reported. CNVs of STRC were most common (73% of CNVs identified) followed by CNVs of OTOA (13% of CNVs identified). Conclusion CNVs are an important cause of NSHL and their detection must be included in comprehensive genetic testing for hearing loss.

2014-01-01

362

Special issues in hearing loss prevention in the Canadian military environment  

Science.gov (United States)

Noise can be particularly noxious to hearing in the military. The personnel regularly face a wide range of noise-hazardous situations, many of which are seldom encountered in other work environments. High noise levels are associated with the operation of small arms and large caliber weapons, combat vehicles, aircrafts, ships and vessels, and industrial equipment. This can induce permanent and temporary hearing loss, compromise speech communication, interfere with the detection and localization of sound sources and warning sounds and thus, can jeopardize life or safety of the personnel. This paper will review the essential elements of a hearing loss prevention program proposed for the Canadian Armed Forces. The ultimate goal is to preserve hearing health as well as all hearing abilities necessary for effective operations. The program has been designed to meet the noise measurement and hazard investigation procedures, limits on noise exposure, use of hearing protection and other regulatory measures contained in the Canadian Occupational Health and Safety (COHS) Regulations (Part VII: Levels of Sound), while addressing the particular nature of the military environment. The paper will focus on issues that are not typically found in other occupational environments (variable work schedules, excessive impulse noise, extended exposures, communication devices).

Giguère, Christian; Laroche, Chantal

2005-04-01

363

Operative findings of conductive hearing loss with intact tympanic membrane and normal temporal bone computed tomography.  

Science.gov (United States)

Despite recent technological advances in diagnostic methods including imaging technology, it is often difficult to establish a preoperative diagnosis of conductive hearing loss (CHL) in patients with an intact tympanic membrane (TM). Especially, in patients with a normal temporal bone computed tomography (TBCT), preoperative diagnosis is more difficult. We investigated middle ear disorders encountered in patients with CHL involving an intact TM and normal TBCT. We also analyzed the surgical results with special reference to the pathology. We reviewed the medical records of 365 patients with intact TM, who underwent exploratory tympanotomy for CHL. Fifty nine patients (67 ears, eight bilateral surgeries) had a normal preoperative TBCT findings reported by neuro-radiologists. Demographic data, otologic history, TM findings, preoperative imaging findings, intraoperative findings, and pre- and postoperative audiologic data were obtained and analyzed. Exploration was performed most frequently in the second and fifth decades. The most common postoperative diagnosis was stapedial fixation with non-progressive hearing loss. The most commonly performed hearing-restoring procedure was stapedotomy with piston wire prosthesis insertion. Various types of hearing-restoring procedures during exploration resulted in effective hearing improvement, especially with better outcome in the ossicular chain fixation group. In patients with CHL who have intact TM and normal TBCT, we should consider an exploratory tympanotomy for exact diagnosis and hearing improvement. Information of the common operative findings from this study may help in preoperative counseling. PMID:23744181

Kim, Se-Hyung; Cho, Yang-Sun; Kim, Hye Jeong; Kim, Hyung-Jin

2014-06-01

364

The Effects of High-Frequency Amplification on the Objective and Subjective Performance of Hearing Instrument Users with Varying Degrees of High-Frequency Hearing Loss  

Science.gov (United States)

Purpose: The purpose of the present study was to determine if amplifying beyond 2 kHz affected the objective and subjective performance of hearing instrument users with varying degrees of mild-to-severe high-frequency sensorineural hearing loss. Method: Twenty participants were fitted binaurally with digital completely-in-the-canal devices with…

Plyler, Patrick N.; Fleck, Erica L.

2006-01-01

365

Non-flat audiograms in sensorineural hearing loss and speech perception  

Directory of Open Access Journals (Sweden)

Full Text Available OBJECTIVE: The audibility thresholds for the sound frequency of 137 upward- and downward-sloping audiograms showing sensorineural hearing loss were selected and analyzed in conjunction with speech recognition thresholds obtained from individuals seen at a public otolaryngology clinic to determine which frequencies in slope audiograms best represent speech recognition thresholds. METHOD: The linear regression model and mean square error were used to determine the associations between the threshold values. RESULT: The mean square error identified larger errors when using thresholds of 500, 1000, and 2000 Hz than when using audibility thresholds of 500, 1000, 2000, and 4000 Hz. The linear regression model showed a higher correlation (91% between the audiogram thresholds for frequencies of 500, 1000, 2000, and 4000 Hz than for the frequencies of 500, 1000, and 2000 Hz (88%. CONCLUSION: Frequencies of 500, 1000, 2000, and 4000 Hz were the most significant in predicting the speech recognition threshold.

Kelly Cristina Lira de Andrade

2013-06-01

366

Effects of Age and Hearing Loss on the Relationship between Discrimination of Stochastic Frequency Modulation and Speech Perception  

Science.gov (United States)

Objective The frequency modulation (FM) of speech can convey linguistic information and also enhance speech-stream coherence and segmentation. Using a clinically oriented approach, the purpose of the present study was to examine the effects of age and hearing loss on the ability to discriminate between stochastic patterns of low-rate FM and determine whether difficulties in speech perception experienced by older listeners relate to a deficit in this ability. Design Data were collected from 18 normal-hearing young adults, and 18 participants who were at least 60 years old, nine normal-hearing and nine with a mild-to-moderate sensorineural hearing loss. Using stochastic frequency modulators derived from 5-Hz lowpass noise applied to a 1-kHz carrier, discrimination thresholds were measured in terms of frequency excursion (?F) both in quiet and with a speech-babble masker present, stimulus duration, and signal-to-noise ratio (SNRFM) in the presence of a speech-babble masker. Speech perception ability was evaluated using Quick Speech-in-Noise (QuickSIN) sentences in four-talker babble. Results Results showed a significant effect of age, but not of hearing loss among the older listeners, for FM discrimination conditions with masking present (?F and SNRFM). The effect of age was not significant for the FM measures based on stimulus duration. ?F and SNRFM were also the two conditions for which performance was significantly correlated with listener age when controlling for effect of hearing loss as measured by pure-tone average. With respect to speech-in-noise ability, results from the SNRFM condition were significantly correlated with QuickSIN performance. Conclusions Results indicate that aging is associated with reduced ability to discriminate moderate-duration patterns of low-rate stochastic FM. Furthermore, the relationship between QuickSIN performance and the SNRFM thresholds suggests that the difficulty experienced by older listeners with speech-in-noise processing may in part relate to diminished ability to process slower fine-structure modulation at low sensation levels. Results thus suggest that clinical consideration of stochastic FM discrimination measures may offer a fuller picture of auditory processing abilities.

Sheft, Stanley; Shafiro, Valeriy; Lorenzi, Christian; McMullen, Rachel; Farrell, Caitlin

2012-01-01

367

A Narrow Internal Auditory Canal with Duplication in a Patient with Congenital Sensorineural Hearing Loss  

Energy Technology Data Exchange (ETDEWEB)

A narrow internal auditory canal (IAC) with duplication is a rare anomaly of the temporal bone. It is associated with congenital sensorineural hearing loss. Aplasia or hypoplasia of the vestibulocochlear nerve may cause the hearing loss. We present an unusual case of an isolated narrow IAC with duplication that was detected by a CT scan. In this case, the IAC was divided by a bony septum into an empty stenotic inferoposterior portion and a large anterosuperior portion containing the facial nerve that was clearly delineated on MRI.

Baik, Hye Won; Yu, Hye On; Kim, Kyung Soo; Kim, Gi Hyeon [Chung-Ang University Hospital, College of Medicine, Seoul (Korea, Republic of)

2008-07-15

368

A Narrow Internal Auditory Canal with Duplication in a Patient with Congenital Sensorineural Hearing Loss  

International Nuclear Information System (INIS)

A narrow internal auditory canal (IAC) with duplication is a rare anomaly of the temporal bone. It is associated with congenital sensorineural hearing loss. Aplasia or hypoplasia of the vestibulocochlear nerve may cause the hearing loss. We present an unusual case of an isolated narrow IAC with duplication that was detected by a CT scan. In this case, the IAC was divided by a bony septum into an empty stenotic inferoposterior portion and a large anterosuperior portion containing the facial nerve that was clearly delineated on MRI

2008-07-01

369

Antioxidant-enriched diet does not delay the progression of age-related hearing loss  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Oxidative stress has been linked to noise- and drug-induced as well as age-related hearing loss. Antioxidants can attenuate the decline of cochlear structure and function after exposure to noise or drugs, but it is debated as to whether they can protect from age-related hearing loss. In a long-term longitudinal study, 10-month old female CBA/J mice were placed on either a control or antioxidant-enriched diet and monitored through 24 months of age. Supplementation with vitamins A, C, and E, L-...

Sha, Su-hua; Kanicki, Ariane; Halsey, Karin; Wearne, Kimberly Anne; Schacht, Jochen

2012-01-01

370

Secondary superficial siderosis of the central nervous system in a patient presenting with sensorineural hearing loss  

Energy Technology Data Exchange (ETDEWEB)

We present a 50-year-old man who was investigated for sensorineural hearing loss. On MRI of the brain superficial siderosis of the central nervous system was seen, while MRI of the spine revealed an ependymoma of the cauda equina. This case illustrates the importance of performing T2-weighted imaging of the brain and posterior fossa when sensorineural hearing loss is present. Spine imaging is mandatory when superficial siderosis of the brain is diagnosed without identification of a bleeding source in the brain. (orig.) With 5 figs., 10 refs.

Lemmerling, M.; De Praeter, G.; Mollet, P.; Mortele, K.; Kunnen, M. [Univ. Hospital, Gent (Belgium). Dept. of Radiol.; Dhooge, I. [Department of Otorhinolaryngology, University Hospital Gent, Gent (Belgium); Mastenbroek, G. [Department of Neurology, Streekziekenhuis De Honte, Terneuzen (Netherlands)

1998-05-01

371

Secondary superficial siderosis of the central nervous system in a patient presenting with sensorineural hearing loss  

International Nuclear Information System (INIS)

We present a 50-year-old man who was investigated for sensorineural hearing loss. On MRI of the brain superficial siderosis of the central nervous system was seen, while MRI of the spine revealed an ependymoma of the cauda equina. This case illustrates the importance of performing T2-weighted imaging of the brain and posterior fossa when sensorineural hearing loss is present. Spine imaging is mandatory when superficial siderosis of the brain is diagnosed without identification of a bleeding source in the brain. (orig.)

1998-05-01

372

Mutations in OTOGL, Encoding the Inner Ear Protein Otogelin-like, Cause Moderate Sensorineural Hearing Loss  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Hereditary hearing loss is characterized by a high degree of genetic heterogeneity. Here we present OTOGL mutations, a homozygous one base pair deletion (c.1430 delT) causing a frameshift (p.Val477Glufs?25) in a large consanguineous family and two compound heterozygous mutations, c.547C>T (p.Arg183?) and c.5238+5G>A, in a nonconsanguineous family with moderate nonsyndromic sensorineural hearing loss. OTOGL maps to the DFNB84 locus at 12q21.31 and encodes otogelin-like, which has structura...

Yariz, Kemal o; Duman, Duygu; Seco, Celia zazo; Dallman, Julia; Huang, Mingqian; Peters, Theo a; Sirmaci, Asli; Lu, Na; Schraders, Margit; Skromne, Isaac; Oostrik, Jaap; Diaz-horta, Oscar; Young, Juan i; Tokgoz-yilmaz, Suna; Konukseven, Ozlem

2012-01-01

373

Hearing and diabetic neuropathy.  

Science.gov (United States)

Hearing was studied audiometrically in 20 diabetic patients with peripheral neuropathy, and the results were compared with those from a group of normal, age-matched subjects. Although the patients gave no history of hearing loss or ear disease, 11 (55%) had symmetrical sensorineural hearing loss involving at least one frequency. Regression analysis demonstrated significantly higher hearing thresholds for the diabetic group at nine of 11 frequencies tested. Decreased hearing acuity in diabetes mellitus may be related to neuropathy of the auditory nerve. PMID:1138672

Friedman, S A; Schulman, R H; Weiss, S

1975-04-01

374

Improvement of bone conduction after stapes surgery in otosclerosis patients with mixed hearing loss depending from surgical technique.  

Science.gov (United States)

This study investigate the effect of stapes surgery on bone conduction (BC) improvement in otosclerotic patients with mixed hearing loss and also compare the effect of three different types of surgery (complete stapedectomy, partial stapedectomy and microfenestration stapedotomy) on this improvement. We retrospectively reviewed surgical database of 84 otosclerotic patients with mixed hearing loss. Sixty-two patients (75%) had significant improvement in BC after surgery (P = 0.03). In 85% of patients with follow-up time longer than 1 year, this improvement had remained. Improvement in BC after surgery was better in partial stapedectomy group (82.6%) and complete stapedectomy group (80.8%) in comparison with microfenestration stapedotomy group (63%) (P = 0.052). PMID:19205715

Karimi Yazdi, Alireza; Sazgar, Amir Arvin; Motiee, Maziar; Ashtiani, Mohammadtaghi Khorsandi

2009-08-01

375

Hearing loss in patients with diabetes mellitus / Perdas auditivas em pacientes portadores de diabetes melito  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in portuguese A literatura especializada descreve que a relação causa e efeito entre diabetes melito e perda auditiva é bastante controversa, visto que, na prática clínica, muitos pacientes apresentam disacusia e outros não. OBJETIVO: Investigar a relação entre perda auditiva e diabetes melito, a fim de contribui [...] r para resultados mais precisos sobre o assunto em pauta. FORMA DE ESTUDO: Estudo clínico com coorte transversal. MATERIAL E MÉTODO: No presente estudo foram analisados os prontuários de 50 indivíduos adultos atendidos nos anos de 2006 e 2007, de ambos os sexos, com idade superior a 45 anos, portadores do diabetes melito, e 50 prontuários de indivíduos que não apresentaram doenças metabólicas. RESULTADOS: A presente pesquisa identificou uma piora dos limiares audiométricos dos pacientes com diabetes melito quando comparados aos do Grupo Controle, com diferença estatisticamente significante. CONCLUSÃO: Os resultados obtidos neste estudo indicam a correlação entre perda auditiva e diabetes melito. Sendo assim, essa possibilidade deve ser investigada pelos profissionais da saúde que trabalham com portadores de diabetes melito, por meio de acompanhamento da saúde auditiva dessa população. Abstract in english The relationship between diabetes mellitus and hearing loss is described as 'controversial' in the literature, given that in the clinical realm many patients present dysacusis while others do not. AIM: this study aims to investigate the relationship between hearing loss and diabetes mellitus and add [...] to the knowledge being developed in this area. STUDY DESIGN: cross-sectional clinical trial. MATERIALS AND METHOD: in our study we analyzed the medical charts of 50 adult patients of both genders, aged above 45 years, and diagnosed with diabetes mellitus, seen in our institution in 2006 and 2007, and compared them to the charts of 50 metabolic disease-free individuals. RESULTS: this study found statistically significant worse audiometric thresholds among patients with diabetes mellitus when compared to patients in the control group. CONCLUSION: the results identified in this study point to a correlation between hearing loss and diabetes mellitus. This possibility should therefore be further investigated by health care workers providing care to patients with diabetes mellitus, in the form of closer follow-up on the auditory health of this patient group.

Thiago Hernandes, Diniz; Heraldo Lorena, Guida.

376

Effects of fundamental frequency and vocal-tract length cues on sentence segregation by listeners with hearing loss.  

Science.gov (United States)

The purpose was to determine the effect of hearing loss on the ability to separate competing talkers using talker differences in fundamental frequency (F0) and apparent vocal-tract length (VTL). Performance of 13 adults with hearing loss and 6 adults with normal hearing was measured using the Coordinate Response Measure. For listeners with hearing loss, the speech was amplified and filtered according to the NAL-RP hearing aid prescription. Target-to-competition ratios varied from 0 to 9 dB. The target sentence was randomly assigned to the higher or lower values of F0 or VTL on each trial. Performance improved for F0 differences up to 9 and 6 semitones for people with normal hearing and hearing loss, respectively, but only when the target talker had the higher F0. Recognition for the lower F0 target improved when trial-to-trial uncertainty was removed (9-semitone condition). Scores improved with increasing differences in VTL for the normal-hearing group. On average, hearing-impaired listeners did not benefit from VTL cues, but substantial inter-subject variability was observed. The amount of benefit from VTL cues was related to the average hearing loss in the 1-3-kHz region when the target talker had the shorter VTL. PMID:21877813

Mackersie, Carol L; Dewey, James; Guthrie, Lesli A

2011-08-01

377

Genome-Wide Association Study for Age-Related Hearing Loss (AHL) in the Mouse: A Meta-Analysis.  

Science.gov (United States)

Age-related hearing loss (AHL) is characterized by a symmetric sensorineural hearing loss primarily in high frequencies and individuals have different levels of susceptibility to AHL. Heritability studies have shown that the sources of this variance are both genetic and environmental, with approximately half of the variance attributable to hereditary factors as reported by Huag and Tang (Eur Arch Otorhinolaryngol 267(8):1179-1191, 2010). Only a limited number of large-scale association studies for AHL have been undertaken in humans, to date. An alternate and complementary approach to these human studies is through the use of mouse models. Advantages of mouse models include that the environment can be more carefully controlled, measurements can be replicated in genetically identical animals, and the proportion of the variability explained by genetic variation is increased. Complex traits in mouse strains have been shown to have higher heritability and genetic loci often have stronger effects on the trait compared to humans. Motivated by these advantages, we have performed the first genome-wide association study of its kind in the mouse by combining several data sets in a meta-analysis to identify loci associated with age-related hearing loss. We identified five genome-wide significant loci (<10(-6)). One of these loci confirmed a previously identified locus (ahl8) on distal chromosome 11 and greatly narrowed the candidate region. Specifically, the most significant associated SNP is located 450 kb upstream of Fscn2. These data confirm the utility of this approach and provide new high-resolution mapping information about variation within the mouse genome associated with hearing loss. PMID:24570207

Ohmen, Jeffrey; Kang, Eun Yong; Li, Xin; Joo, Jong Wha; Hormozdiari, Farhad; Zheng, Qing Yin; Davis, Richard C; Lusis, Aldons J; Eskin, Eleazar; Friedman, Rick A

2014-06-01

378

Confirmation of diagnosis in Romanian children with DFNB1 related hearing loss  

Directory of Open Access Journals (Sweden)

Full Text Available DFNB1 locus has been linked to a nonsyndromic “invisible disability” called congenital sensorineural hearing loss and deafness. Mutations of GJB2 and GJB6 genes are associated with deafness at the DFNB1 locus. The diagnosis of DFNB1 is made with molecular genetic testing. DNA-based testing can be used both prenatally and postnatally. Purpose: to get evidence for implementation of newborn hearing screening programs at national level; to use the molecular testing of children at risk for confirmation of diagnosis and early intervention. OAEs and ABR were performed for 4303 newborns. Audiologic evaluation of 38 children suspected of having hearing loss was performed too. Physical examinations and family history were used to get information about congenital deafness. DNA from blood samples was isolated, and two PCR multiplex assays were developed to detect DFNB1 mutations. Only 23 newborns were screened positive. Newborns were referred to audiologic evaluation, genetic counseling and testing for the etiologic diagnosis. Physical examination revealed no other abnormal findings. GJB2 mutations were detected in 36.03% of patients, and all of them have 35delG mutation. None of them was found to have GJB6 mutations. Our results suggested that molecular testing was an accurate method of early determining cause of congenital hearing loss and helped us to exclude GJB6 gene from the routine hearing screening protocol.

Cristina Dragomir

2013-10-01

379

Drug delivery to the inner ear: strategies and their therapeutic implications for sensorineural hearing loss.  

Science.gov (United States)

Hearing aids or cochlear implants constitute almost exclusively the treatment options currently available to patients suffering from sensorineural hearing loss and related conditions, such as noise-induced hearing loss, ototoxicity or autoimmune inner ear disease. While some systemic treatments exist, they generally exert adverse secondary effects and their efficacy is hampered by the blood-cochlear barrier that limits drug access to the inner ear. Hence, the new therapies that are being developed for hearing loss focus on strategies for direct drug delivery to the inner ear. The passive and active methods for local delivery can be categorized into two general groups: intratympanic or intracochlear. The intratympanic approach is a non-invasive method that preserves hearing and takes advantage of the permeability of the round window to gain access to the cochlea. However, this technique is limited by not knowing the dose of the drug that reaches the cochlea, (a handicap which might be overcome by the use of tagged drugs). While direct access to the inner ear by intracochlear administration avoids this problem, this method requires surgery. Currently, laboratory animals are being used to explore which therapeutic approaches are best suited to address this problem. These include cochleostomy and the insertion of devices that pump drugs into the inner ear without inducing cochlear damage. In this article, we review the different techniques under evaluation in animal models of deafness, and their potential use for drug delivery and treatment of human inner ear diseases. PMID:22283653

Rivera, Teresa; Sanz, Lorena; Camarero, Guadalupe; Varela-Nieto, Isabel

2012-05-01

380

Consonant errors and remediation in sensorineural hearing loss.  

Science.gov (United States)

An analysis of consonant errors for hearing-impaired subjects in a multiple-choice format revealed that about 14 consonants caused most of the difficulty in consonant recognition. For a given consonant, error probability was typically lower in the initial position of the stimulus word than in the final position. When errors were made, the substitutions were limited typically to two or three other consonants, with a greater variety occurring for consonants in the final position. Substitutions tended to be the same over a wide range of pure-tone configurations. Place errors were predominant, but manner errors also occurred. In only a few instances did specific relationships occur between particular stimulus consonants and pure-tone configurations. With knowledge of the error consonants and typical substitutions, auditory recognition of consonants can be improved by programmed instruction methods. Shaping can be accomplished by a manipulation of the response foils (choices). Since it has been shown that visual recognition of consonants can also be improved, advantage can be taken of both the visual and auditory modalities in remedial procedures. Frequency of usage in the language should be considered in the ordering of consonants for retraining purposes. Work in consonant recognition should be beneficial to the hearing-impaired patient as part of a total rehabilitation program. PMID:692099

Owens, E

1978-08-01

 
 
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