WorldWideScience
1

Correlation of pre-veterinary admissions criteria, intra-professional curriculum measures, AVMA-COE professional competency scores, and the NAVLE.  

Science.gov (United States)

Data consisting of preadmission criteria scores, annual and final cumulative grade point averages (GPAs), grades from individual professional courses, American Veterinary Medical Association Council on Education (AVMA-COE) Competency scores, annual class rank, and North American Veterinary Licensing Exam (NAVLE) scores were collected on all graduating DVM students at Kansas State University in 2009 and 2010. Associations among the collected data were compared by Pearson correlation. Pre-veterinary admissions criteria infrequently correlated with annual GPAs of Years 1-3, rarely correlated with the AVMA-COE Competencies, and never correlated with the annual GPA of Year 4. Low positive correlations occurred between the NAVLE and the Verbal Graduate Record Examination (GRE) (r=.214), Total GRE (r=.171), and the mean GPA of pre-professional science courses (SGPA) (r=.236). Annual GPAs strongly correlated with didactic course scores. Annual GPAs and final class rank strongly correlated (mean r=-.849), and both strongly correlated with the NAVLE score (NAVLE: GPAs mean r=.628, NAVLE: final class rank r=-.714). Annual GPAs at the end of Years 1-4 weakly correlated or did not correlate with the AVMA-COE Competencies. The AVMA-COE Competencies weakly correlated with scores earned in didactic courses of Years 1-3. AVMA-COE Competencies were internally consistent (mean r=.796) but only moderately correlated with performance on the NAVLE (mean r=.319). Low correlations between admissions criteria and outcomes indicate a need to reevaluate admission criteria as predictors of school success. If the NAVLE remains the primary discriminator for veterinary licensure (and the gateway to professional activity), then the AVMA-COE Competencies should be refined to better improve and reflect the NAVLE, or the NAVLE examination should change to reflect AVMA-COE Competencies. PMID:24152428

Roush, James K; Rush, Bonnie R; White, Brad J; Wilkerson, Melinda J

2014-01-01

2

7 CFR 1703.126 - Criteria for scoring grant applications.  

Science.gov (United States)

...1703.126 Criteria for scoring grant applications. (a...address each of the following scoring criteria: (1) The need...The cost effectiveness of the system (up to 35 points); ...up to 15 points). (b) Scoring criteria: (1) The...

2010-01-01

3

Criteria for measures of quantum correlations  

CERN Document Server

Entanglement does not describe all quantum correlations and several authors have shown the need to go beyond entanglement when dealing with mixed states. Several different measures have sprung up in the literature, for a variety of reasons, To describe quantum correlations; some are known under the collective name quantum discord. Yet, in the same sprit as the criteria for entanglement measures, there is no general mechanism that determines whether a measure of quantum and classical correlations is a proper measure of correlations. This is partially due to the fact that the answer is a bit muddy. In this article we attempt tackle this muddy topic by writing down several criteria for a "good" measure of correlations. We breakup our list into necessary, reasonable, and debatable conditions. We then proceed to prove several of these conditions for generalized measures of quantum correlations. However, not all conditions are met by all measures; we show this via several examples. The reasonable conditions are rel...

Brodutch, Aharon

2011-01-01

4

Correlation tensor criteria for genuine multiqubit entanglement  

OpenAIRE

We present a development of a geometric approach to entanglement indicators. The method is applied to detect genuine multiqubit entanglement. The criteria are given in form of non-linear conditions imposed on correlation tensors. Thus they involve directly observable quantities, and in some cases require only few specific measurements to find multiqubit entanglement. The non-linearity of each of the criteria allows detection of entanglement in wide classes of states. In cont...

Laskowski, Wieslaw; Markiewicz, Marcin; Paterek, Tomasz; Zukowski, Marek

2011-01-01

5

Personality and Examination Score Correlates of Abnormal Psychology Course Ratings.  

Science.gov (United States)

The relationship between the ratings students assigned to an evening undergraduate abnormal psychology class and their scores on objective personality tests and course examinations was investigated. Students (N=70) completed the MMPI and made global ratings of the course; these scores were correlated separately by sex with the T scores of 13 MMPI…

Pauker, Jerome D.

6

Examining Classification Criteria: A Comparison of Three Cut Score Methods  

Science.gov (United States)

This study compared 3 different methods of creating cut scores for a screening instrument, T scores, receiver operating characteristic curve (ROC) analysis, and the Rasch rating scale method (RSM), for use with the Behavioral and Emotional Screening System (BESS) Teacher Rating Scale for Children and Adolescents (Kamphaus & Reynolds, 2007). Using…

DiStefano, Christine; Morgan, Grant

2011-01-01

7

Correlation tensor criteria for genuine multiqubit entanglement  

CERN Document Server

We present a development of a geometric approach to entanglement indicators. The method is applied to detect genuine multiqubit entanglement. The criteria are given in form of non-linear conditions imposed on correlation tensors. Thus they involve directly observable quantities, and in some cases require only few specific measurements to find multiqubit entanglement. The non-linearity of each of the criteria allows detection of entanglement in wide classes of states. In contrast to entanglement witnesses, which in the space of Hermitian operators define a hyperplane, the new conditions define a geometric figure encapsulating the non-fully entangled states within it.

Laskowski, Wieslaw; Paterek, Tomasz; Zukowski, Marek

2011-01-01

8

HER2 amplification, overexpression and score criteria in esophageal adenocarcinoma  

OpenAIRE

The HER2 oncogene was recently reported to be amplified and overexpressed in esophageal adenocarcinoma. However, the relationship of HER2 amplification in esophageal adenocarcinoma with prognosis has not been well defined. The scoring systems for clinically evaluating HER2 in esophageal adenocarcinoma are not established. The aims of the study were to establish a HER2 scoring system and comprehensively investigate HER2 amplification and overexpression in esophageal adenocarcinoma and its prec...

Hu, Yingchuan; Bandla, Santhoshi; Godfrey, Tony E.; Tan, Dongfeng; Luketich, James D.; Pennathur, Arjun; Qiu, Xing; Hicks, David G.; Peters, Jeffrey; Zhou, Zhongren

2011-01-01

9

Correlations between knee society function scores and functional force measures.  

Science.gov (United States)

Subjective evaluations often are used after knee arthroplasty to quantify function; however, these scores may be influenced by pain and/or function of the nonoperated limb. Multiple influences increase variability of these scores, which in turn may result in a greater change in score required to be considered clinically important. We determined the relationships among the Knee Society pain and function scores, range of motion (ROM), and functional force measures of the surgically treated and nonoperated limbs. Before and 3 months after total or unicompartmental knee arthroplasty, 36 patients answered questions necessary to calculate the Knee Society pain and function scores. A dual-force platform was used to record the lift-up force of each limb during a stepping task. Function scores were correlated to pain scores, lift-up force of the nonoperated limb, and ROM before surgery. After surgery, function scores correlated with pain scores but not with objective functional measures or ROM. As patient-reported function scores and functional force measures of the surgically treated limb seem to provide distinctly different information, both measures may need to be collected after knee arthroplasty to fully understand a patient's functional recovery. PMID:19343460

Jacobs, Cale A; Christensen, Christian P

2009-09-01

10

The relationship between the ability to identify evaluation criteria and integrity test scores  

Directory of Open Access Journals (Sweden)

Full Text Available It has been argued that applicants who have the ability to identify what kind of behavior is evaluated positively in a personnel selection situation can use this information to adapt their behavior accordingly. Although this idea has been tested for assessment centers and structured interviews, it has not been studied with regard to integrity tests (or other personality tests. Therefore, this study tested whether candidates’ ability to identify evaluation criteria (ATIC correlates with their integrity test scores. Candidates were tested in an application training setting (N = 92. The results supported the idea that ATIC also plays an important role for integrity tests. New directions for future research are suggested based on this finding.

CORNELIUS J. KÖNIG

2006-09-01

11

Vitiligo Extent Tensity Index (VETI) score: a new definition, assessment and treatment evaluation criteria in vitiligo  

OpenAIRE

Although skin is the largest organ of the body, there are no standardized reproducible methods for assessing severity of many skin diseases. Due to lack of consensus, methods of assessment and inexistence of precise scoring system, there is no application for vitiligo estimation in real practice. In this paper the author describes VETI score as a new treatment evaluation criteria and severity assessment method for vitiligo. This new tool, as does the PASI score in psoriasis, may be able to pr...

Feily, Amir

2014-01-01

12

Multi-criteria neutrosophic decision making method based on score and accuracy functions under neutrosophic environment  

OpenAIRE

A neutrosophic set is a more general platform, which can be used to present uncertainty, imprecise, incomplete and inconsistent. In this paper a score function and an accuracy function for single valued neutrosophic sets is firstly proposed to make the distinction between them. Then the idea is extended to interval neutrosophic sets. A multi-criteria decision making method based on the developed score-accuracy functions is established in which criterion values for alternativ...

S?ahin, R?dvan

2014-01-01

13

Automatic sleep scoring in normals and in individuals with neurodegenerative disorders according to new international sleep scoring criteria.  

Science.gov (United States)

The aim of this study was to develop a fully automatic sleep scoring algorithm on the basis of a reproduction of new international sleep scoring criteria from the American Academy of Sleep Medicine. A biomedical signal processing algorithm was developed, allowing for automatic sleep depth quantification of routine polysomnographic recordings through feature extraction, supervised probabilistic Bayesian classification, and heuristic rule-based smoothing. The performance of the algorithm was tested using 28 manually classified day-night polysomnograms from 18 normal subjects and 10 patients with Parkinson disease or multiple system atrophy. This led to quantification of automatic versus manual epoch-by-epoch agreement rates for both normals and abnormals. Resulting average agreement rates were 87.7% (Cohen's Kappa: 0.79) and 68.2% (Cohen's Kappa: 0.26) in the normal and abnormal group, respectively. Based on an observed reliability of the manual scorer of 92.5% (Cohen's Kappa: 0.87) in the normal group and 85.3% (Cohen's Kappa: 0.73) in the abnormal group, this study concluded that although the developed algorithm was capable of scoring normal sleep with an accuracy around the manual interscorer reliability, it failed in accurately scoring abnormal sleep as encountered for the Parkinson disease/multiple system atrophy patients. PMID:20634706

Jensen, Peter S; Sorensen, Helge B D; Leonthin, Helle L; Jennum, Poul

2010-08-01

14

Automatic sleep scoring in normals and in individuals with neurodegenerative disorders according to new international sleep scoring criteria  

DEFF Research Database (Denmark)

The aim of this study was to develop a fully automatic sleep scoring algorithm on the basis of a reproduction of new international sleep scoring criteria from the American Academy of Sleep Medicine. A biomedical signal processing algorithm was developed, allowing for automatic sleep depth quantification of routine polysomnographic recordings through feature extraction, supervised probabilistic Bayesian classification, and heuristic rule-based smoothing. The performance of the algorithm was tested using 28 manually classified day-night polysomnograms from 18 normal subjects and 10 patients with Parkinson disease or multiple system atrophy. This led to quantification of automatic versus manual epoch-by-epoch agreement rates for both normals and abnormals. Resulting average agreement rates were 87.7% (Cohen's Kappa: 0.79) and 68.2% (Cohen's Kappa: 0.26) in the normal and abnormal group, respectively. Based on an observed reliability of the manual scorer of 92.5% (Cohen's Kappa: 0.87) in the normal group and 85.3% (Cohen's Kappa: 0.73) in the abnormal group, this study concluded that although the developed algorithm was capable of scoring normal sleep with an accuracy around the manual interscorer reliability, it failed in accurately scoring abnormal sleep as encountered for the Parkinson disease/multiple system atrophy patients.

Jensen, Peter S; Sorensen, Helge B D

2010-01-01

15

Automatic Sleep Scoring in Normals and in Individuals with Neurodegenerative Disorders According to New International Sleep Scoring Criteria  

DEFF Research Database (Denmark)

The aim of this study was to develop a fully automatic sleep scoring algorithm on the basis of a reproduction of new international sleep scoring criteria from the American Academy of Sleep Medicine. A biomedical signal processing algorithm was developed, allowing for automatic sleep depth quantification of routine polysomnographic recordings through feature extraction, supervised probabilistic Bayesian classification, and heuristic rule-based smoothing. The performance of the algorithm was tested using 28 manually classified day-night polysomnograms from 18 normal subjects and 10 patients with Parkinson disease or multiple system atrophy. This led to quantification of automatic versus manual epoch-by-epoch agreement rates for both normals and abnormals. Resulting average agreement rates were 87.7% (Cohen's Kappa: 0.79) and 68.2% (Cohen's Kappa: 0.26) in the normal and abnormal group, respectively. Based on an observed reliability of the manual scorer of 92.5% (Cohen's Kappa: 0.87) in the normal group and 85.3% (Cohen's Kappa: 0.73) in the abnormal group, this study concluded that although the developed algorithm was capable of scoring normal sleep with an accuracy around the manual interscorer reliability, it failed in accurately scoring abnormal sleep as encountered for the Parkinson disease/multiple system atrophy patients.

Jensen, Peter S.; SØrensen, Helge Bjarup Dissing

2010-01-01

16

Equivalence of digital image correlation criteria for pattern matching.  

Science.gov (United States)

In digital image correlation (DIC), to obtain the displacements of each point of interest, a correlation criterion must be predefined to evaluate the similarity between the reference subset and the target subset. The correlation criterion is of fundamental importance in DIC, and various correlation criteria have been designed and used in literature. However, little research has been carried out to investigate their relations. In this paper, we first provide a comprehensive overview of various correlation criteria used in DIC. Then we focus on three robust and most widely used correlation criteria, i.e., a zero-mean normalized cross-correlation (ZNCC) criterion, a zero-mean normalized sum of squared difference (ZNSSD) criterion, and a parametric sum of squared difference (PSSD(ab)) criterion with two additional unknown parameters, since they are insensitive to the scale and offset changes of the target subset intensity and have been highly recommended for practical use in literature. The three correlation criteria are analyzed to establish their transversal relationships, and the theoretical analyses clearly indicate that the three correlation criteria are actually equivalent, which elegantly unifies these correlation criteria for pattern matching. Finally, the equivalence of these correlation criteria is further validated by numerical simulation and actual experiment. PMID:20885489

Pan, Bing; Xie, Huimin; Wang, Zhaoyang

2010-10-01

17

Diffuse Fatty Infiltration of the Liver: US Scoring System Correlated with CT and LFT  

International Nuclear Information System (INIS)

The present study was performed to estimate the accuracy of US examination in predicting the hepatic function in patients with diffuse fatty infiltration of the Liver. We compared the findings at US with the findings at CT and biochemical hepatic function test. US was performed by using 3.5MHz sector prove. We evaluated the US findings in terms or the degree of acoustic attenuation from the liver, the parenchymal echogenicity, the distinction of the portal vein wall, and the distinction of the diaphragm. Each parameter was graded into the numeric scores ranging from 0 to 2. The total US score was calculated from the scores of the four parameters. The total US score was compared with the difference in Hounsfield Units between the liver and spleen on nonenhanced CT images. The total US score was also compared with the aspartate(AST) and alanine transaminase(ALT) levels in peripheral blood. There was statistically significant correlation between the total US score and the difference in Hounsfield Unit between the liver and spleen on CT (r=0.7074, p<0.0001). When the total US score above 4 was considered as acriteria, the AST or ALT level were abnormal within the sensitivity of 90% and specificity of 60%. When the total US score above 5 was considered as a criteria, the sensitivity and specificity were 78% and 79%, respectively. In conclusion, US scoring system is useful in predicting the abnormal hepatic function in patients with diffuse fatty infiltration of the liver diffuse fatty infiltration of the liver

18

Metabolic syndrome criteria as predictors of subclinical atherosclerosis based on the coronary calcium score  

Science.gov (United States)

Background/Aims The aim was to determine which of three sets of metabolic syndrome (MetS) criteria (International Diabetes Federation [IDF], National Cholesterol Education Program Adult Treatment Panel III [ATP III], and European Group for the Study of Insulin Resistance [EGIR]) best predicts the coronary artery calcification (CAC) score in a cross-sectional study. This has not been evaluated in previous studies. Methods A total of 24,060 subjects were screened for CAC by multi-detector computed tomography. The presence of CAC was defined as a CAC score > 0. The odds ratio for the presence of CAC was analyzed for three different sets of MetS criteria and according to number of MetS components. Results CAC was observed in 12.6% (3,037) of the subjects. Patients with MetS, as defined by the IDF, ATP III, and EGIR criteria, had a CAC rate of 23.0%, 25.1%, and 29.5%, respectively (p < 0.001). Comparisons of C statistics for multivariate regression models revealed no significant difference among the three sets of criteria. After adjustment for risk factors, the ATP III criteria produced a slightly higher odds ratio for CAC compared with the other criteria, but this difference was not significant. The risk factor-adjusted odds ratio for the presence of CAC increased from 1 to 1.679 as the number of MetS components defined by ATP III increased from 0 to ? 3 (p for trend < 0.001). Conclusions The presence of MetS was associated with the presence of CAC. There was no significant difference among the three sets of MetS criteria in terms of the ability to predict CAC. An increase in the number of MetS components was associated with an increased odds of CAC. PMID:25589838

Seo, Mi Hae; Rhee, Eun-Jung; Park, Se Eun; Park, Cheol Young; Oh, Ki Won; Park, Sung Woo

2015-01-01

19

Metabolic syndrome criteria as predictors of subclinical atherosclerosis based on the coronary calcium score  

Science.gov (United States)

Background/Aims The aim was to determine which of three sets of metabolic syndrome (MetS) criteria (International Diabetes Federation [IDF], National Cholesterol Education Program Adult Treatment Panel III [ATP III], and European Group for the Study of Insulin Resistance [EGIR]) best predicts the coronary artery calcification (CAC) score in a cross-sectional study. This has not been evaluated in previous studies. Methods A total of 24,060 subjects were screened for CAC by multi-detector computed tomography. The presence of CAC was defined as a CAC score > 0. The odds ratio for the presence of CAC was analyzed for three different sets of MetS criteria and according to number of MetS components. Results CAC was observed in 12.6% (3,037) of the subjects. Patients with MetS, as defined by the IDF, ATP III, and EGIR criteria, had a CAC rate of 23.0%, 25.1%, and 29.5%, respectively (p < 0.001). Comparisons of C statistics for multivariate regression models revealed no significant difference among the three sets of criteria. After adjustment for risk factors, the ATP III criteria produced a slightly higher odds ratio for CAC compared with the other criteria, but this difference was not significant. The risk factor-adjusted odds ratio for the presence of CAC increased from 1 to 1.679 as the number of MetS components defined by ATP III increased from 0 to ? 3 (p for trend < 0.001). Conclusions The presence of MetS was associated with the presence of CAC. There was no significant difference among the three sets of MetS criteria in terms of the ability to predict CAC. An increase in the number of MetS components was associated with an increased odds of CAC.

Seo, Mi Hae; Rhee, Eun-Jung; Park, Se Eun; Park, Cheol Young; Oh, Ki Won; Park, Sung Woo

2015-01-01

20

A Chronic Fatigue Syndrome (CFS) severity score based on case designation criteria  

OpenAIRE

Background: Chronic Fatigue Syndrome case designation criteria are scored as physicians’ subjective, nominal interpretations of patient fatigue, pain (headaches, myalgia, arthralgia, sore throat and lymph nodes), cognitive dysfunction, sleep and exertional exhaustion. Methods: Subjects self-reported symptoms using an anchored ordinal scale of 0 (no symptom), 1 (trivial complaints), 2 (mild), 3 (moderate), and 4 (severe). Fatigue of 3 or 4 distinguished “Fatigued” from “Not Fatigued”...

Baraniuk, James N.; Adewuyi, Oluwatoyin; Merck, Samantha Jean; Ali, Mushtaq; Ravindran, Murugan K.; Timbol, Christian R.; Rayhan, Rakib; Zheng, Yin; Le, Uyenphuong; Esteitie, Rania; Petrie, Kristina N.

2013-01-01

21

Spectrophotometric skin measurements correlate with EORTC/RTOG-common toxicity criteria  

International Nuclear Information System (INIS)

Purpose: it was investigated whether the elementary EORTC/RTOG-CTC score (Common Toxicity Criteria) for radiotherapy skin reactions correlates with spectrophotometric measurements of the skin color. Patients, material, and methods: in 41 patients irradiated for unilateral breast cancer the regular scoring by CTC was done during radiotherapy. In parallel, a total of 4,920 spectrophotometric measurements to determine the skin color were performed at baseline, at the beginning of radiotherapy, and at 20, 40 and 60 Gy. The nonirradiated contralateral breast was used for control measurements. Results: as expected, the skin color (especially red) depended on the radiation dose applied to the skin. The objective spectrophotometric measurements were found to correlate well with the subjective CTC scores. Conclusion: for classification of acute radiation toxicity there seems to be no need to replace the common CTC scoring by technical methods. (orig.)

22

Vitiligo Extent Tensity Index (VETI) score: a new definition, assessment and treatment evaluation criteria in vitiligo  

Science.gov (United States)

Although skin is the largest organ of the body, there are no standardized reproducible methods for assessing severity of many skin diseases. Due to lack of consensus, methods of assessment and inexistence of precise scoring system, there is no application for vitiligo estimation in real practice. In this paper the author describes VETI score as a new treatment evaluation criteria and severity assessment method for vitiligo. This new tool, as does the PASI score in psoriasis, may be able to produce a constant and reproducible number and to help clinical research on vitiligo patients. Additionally it has a potential to be a source of any computed application for researchers working on vitiligo patients. PMID:25396094

Feily, Amir

2014-01-01

23

Evaluation of utility in shoulder pathology: Correlating the American Shoulder and Elbow Surgeons and Constant scores to the EuroQoL  

Directory of Open Access Journals (Sweden)

Full Text Available AIM: To study whether health utility scores can be derived from shoulder-specific scores. METHODS: Authors investigated two questions: (1 do the American Shoulder and Elbow Surgeons (ASES score and the Constant score correlate with the EuroQoL (EQ-5D, a measure of health utility? (2 can the ASES and Constant scores be obtained from a complete study sample without bias? Thirty subjects with various shoulder diagnoses completed ASES, Constant, and EQ-5D instruments. Pearson correlations were calculated to assess the associations between EQ-5D score and ASES and Constant scores. RESULTS: The correlation between EQ-5D score and ASES score was 0.60 (P < 0.001; it was 0.54 for EQ-5D and Constant scores (P < 0.003. A multiple regression model containing ASES score, Constant score, age, and gender failed to adequately predict EQ-5D. Moreover, 25% of patients meeting the inclusion criteria did not complete the ASES questionnaire because they did not feel that specific questions, such as “do usual sport - list” and “throw ball overhand,” applied to them. CONCLUSION: Authors’ results do not support the use of the ASES and Constant scores in predicting EuroQol health utility values. However, the Constant score was more suitable for this patient population because all patients were able to complete it.

Blaine T Bafus

2012-01-01

24

Diagnostic accuracy of modified kenneth jones scoring criteria (mkjsc) in confirmed cases of tuberculosis in children  

International Nuclear Information System (INIS)

Background: Tuberculosis (TB) is a granulomatous disease caused by Mycobacterium tuberculosis. The gold standard for the diagnosis of tuberculosis is detection of Mycobacterium tubercle bacilli. However, clinical scoring systems are most widely used for the diagnosis of TB in children. Objective: To determine the diagnostic accuracy of modified Kenneth Jones scoring criteria (MKJSC) in conformed cases of tuberculosis. Methodology: This cross-sectional comparative study was conducted in the department of Paediatrics, King Edward Medical University / Mayo Hospital, Lahore from January to June 2007. One hundred children below 15 years of age were enrolled. They were diagnosed as suspected cases of TB on the basis of fever and cough for more than 15 days. MKJSC was applied and each child was subjected to confirmatory test for TB. Results: There was an overall male preponderance of 54%. The mean age of study population was 1.8 +- 0.7 years. Out of 100 children, 66% were diagnosed as TB cases (23 with confirmatory tests and 43 with MKJSC of 5 or more). Sensitivity, specificity, positive and negative predictive value of MKJSC was 73.91%, 44.16%, 28.33%, and 85% respectively. Diagnostic accuracy of MKJSC was 51%. Conclusion: Present study does not support the hypothesis that MKJSC is a good alternative to confirmatory tests to diagnose tuberculosis in children. However, MKJSC is a simple tool, which can be applied to improve the case detection rate in the absence of sophisticated tests. (author)

25

Correlation of the score for subjective pain with physical disability, clinical and radiographic scores in recent onset rheumatoid arthritis  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background To analyse the relationship between subjective pain score and other measures of clinical, radiographic and functional status; in particular Larsen radiographic scores and Health Assessment Questionnaire (HAQ; in patients with severe rheumatoid arthritis (RA with a disease duration of less than 3 years. Methods In this cross sectional study of 105 patients with RA (76 women, 29 men: mean age 50.93; mean disease duration 15.86 months; 71% rheumatoid factor positive subjective pain was assessed according to the Visual Analog Scale (VAS. Correlation coefficients between pain score and disease activity measures (patients' global assessment of disease by VAS, number of tender and swollen joints, morning stiffness, erythrocyte sedimentation rate [ESR], C-reactive protein [CRP] and titre of rheumatoid factor, radiographic evaluations (Larsen-Dale scores for radiographic damage of the small joints of the hands, wrist and feet, disability measures (health assessment questionnaire [HAQ], and demographic variables were calculated; hierarchical regression analysis was done with subjective pain score as the dependent variable. Results The Spearman's correlation coefficient comparing subjective pain and HAQ was 0.421 (p 0.05. In regression analysis, global assessment of disease by patients explained 32.8% of the variation in pain intensity score, morning stiffness 10.7%, CRP 4.0%, HAQ 3.8% and Larsen-Dale scores explained 2.1%; other variables were not significant in the model. Conclusions Pain scores of patients with early severe rheumatoid arthritis are correlated at higher levels with patients' global assessment of disease and with morning stiffness rather than with radiographic or other clinical variables such as number of tender and swollen joints.

Turiel Maurizio

2002-07-01

26

Correlation-tensor criteria for genuine multiqubit entanglement  

Energy Technology Data Exchange (ETDEWEB)

We present a development of a geometric approach to entanglement indicators. The method is applied to detect genuine multiqubit entanglement. The criteria are given in the form of nonlinear conditions imposed on correlation tensors. Thus they involve directly observable quantities, and in some cases require only few specific measurements to find multiqubit entanglement. The nonlinearity of each of the criteria allows detection of entanglement in wide classes of states. In contrast to entanglement witnesses, which in the space of Hermitian operators define a hyperplane, these conditions define a geometric figure encapsulating the nonfully entangled states within it.

Laskowski, Wieslaw; Markiewicz, Marcin; Zukowski, Marek [Institute of Theoretical Physics and Astrophysics, University of Gdansk, 80-952 Gdansk (Poland); Paterek, Tomasz [Centre for Quantum Technologies, National University of Singapore, Singapore 117543 (Singapore)

2011-12-15

27

Effects of response sets on NEO-PI-R scores and their relations to external criteria.  

Science.gov (United States)

Validity scales indicate the extent to which the results of a self-report inventory are a valid indicator of the test taker's psychological functioning. Validity scales generally are designed to detect the common response sets of positive impression management (underreporting, or faking good), negative impression management (overreporting, or faking bad), and random responding. The revised NEO Personality Inventory (NEO-PI-R; Costa & McCrae, 1992b) is a popular personality assessment tool based on the 5-factor model of personality and is used in a variety of settings. The NEO-PI-R does not include objective validity scales to screen for positive or negative impression management. The purpose of this study was to examine the utility of recently proposed validity scales for detecting these response sets on the NEO-PI-R (Schinka, Kinder, & Kremer, 1997) and to examine the effects of positive and negative impression management on correlations between the NEO-PI-R and external criteria (the Interpersonal Adjective Scale-Revised-B5 [Wiggins & Trapnell, 1997] and the NEO-PI-R Form R). The validity scales discriminated with reasonable accuracy between standard responding and the 2 response sets. Additionally, most correlations between the NEO-PI-R and external criteria were significantly lower when participants were dissimulating than when responding to standard instructions. It appears that response sets of positive and negative impression management may pose a significant threat to the external validity of the NEO-PI-R and that validity scales for their detection might be a useful addition to the inventory. PMID:10900573

Caldwell-Andrews, A; Baer, R A; Berry, D T

2000-06-01

28

SCORE: A novel multi-criteria decision analysis approach to assessing the sustainability of contaminated land remediation.  

Science.gov (United States)

The multi-criteria decision analysis (MCDA) method provides for a comprehensive and transparent basis for performing sustainability assessments. Development of a relevant MCDA-method requires consideration of a number of key issues, e.g. (a) definition of assessment boundaries, (b) definition of performance scales, both temporal and spatial, (c) selection of relevant criteria (indicators) that facilitate a comprehensive sustainability assessment while avoiding double-counting of effects, and (d) handling of uncertainties. Adding to the complexity is the typically wide variety of inputs, including quantifications based on existing data, expert judgements, and opinions expressed in interviews. The SCORE (Sustainable Choice Of REmediation) MCDA-method was developed to provide a transparent assessment of the sustainability of possible remediation alternatives for contaminated sites relative to a reference alternative, considering key criteria in the economic, environmental, and social sustainability domains. The criteria were identified based on literature studies, interviews and focus-group meetings. SCORE combines a linear additive model to rank the alternatives with a non-compensatory approach to identify alternatives regarded as non-sustainable. The key strengths of the SCORE method are as follows: a framework that at its core is designed to be flexible and transparent; the possibility to integrate both quantitative and qualitative estimations on criteria; its ability, unlike other sustainability assessment tools used in industry and academia, to allow for the alteration of boundary conditions where necessary; the inclusion of a full uncertainty analysis of the results, using Monte Carlo simulation; and a structure that allows preferences and opinions of involved stakeholders to be openly integrated into the analysis. A major insight from practical application of SCORE is that its most important contribution may be that it initiates a process where criteria otherwise likely ignored are addressed and openly discussed between stakeholders. PMID:25594905

Rosén, Lars; Back, Pär-Erik; Söderqvist, Tore; Norrman, Jenny; Brinkhoff, Petra; Norberg, Tommy; Volchko, Yevheniya; Norin, Malin; Bergknut, Magnus; Döberl, Gernot

2015-04-01

29

Ultrafast CT scoring system for assessing bronchopulmonary dysplasia. Reproducibility and clinical correlation  

International Nuclear Information System (INIS)

To evaluate the reproducibility of the Ultrafast CT (UFCT) scoring system and assess its usefulness in monitoring clinical severity in infants with bronchopulmonary dysplasia (BPD). UFCT scoring was done in 22 infants (15 boys and 7 girls aged 1 to 37 months) with BPD. A total of 258 lung fields were evaluated for the presence of hyperaeration, linear opacities, triangular subpleural opacities, and bronchovascular bundle distortion or thickening, and UFCT scores were given. Intraobserver and interobserver agreement and reproducibility of UFCT scores were statistically analyzed. In 12 patients, UFCT scores were linearly correlated with clinical severity scores based on respiratory dysfunction and complexity of care. 'Hyperaeration,' which was the most frequent (18 of 22, 81.8%) finding, showed high concordance (?=0.73, p<0.001, ?=0.59, p<0.001), and its UFCT scores significantly correlated with intraobserver and interobserver analyses (r=0.94, p<0.001, r=0.82, p<0.001, respectively). UFCT scores for hyperaeration significantly correlated with clinical scores (r=0.75, p<0.01), whereas those for the others did not. UFCT is useful for assessing BPD. Hyperaeration was the most common and reproducible finding, and its extent significantly correlated with clinical severity. (author)

30

Ultrafast CT scoring system for assessing bronchopulmonary dysplasia. Reproducibility and clinical correlation  

Energy Technology Data Exchange (ETDEWEB)

To evaluate the reproducibility of the Ultrafast CT (UFCT) scoring system and assess its usefulness in monitoring clinical severity in infants with bronchopulmonary dysplasia (BPD). UFCT scoring was done in 22 infants (15 boys and 7 girls aged 1 to 37 months) with BPD. A total of 258 lung fields were evaluated for the presence of hyperaeration, linear opacities, triangular subpleural opacities, and bronchovascular bundle distortion or thickening, and UFCT scores were given. Intraobserver and interobserver agreement and reproducibility of UFCT scores were statistically analyzed. In 12 patients, UFCT scores were linearly correlated with clinical severity scores based on respiratory dysfunction and complexity of care. `Hyperaeration,` which was the most frequent (18 of 22, 81.8%) finding, showed high concordance ({kappa}=0.73, p<0.001, {kappa}=0.59, p<0.001), and its UFCT scores significantly correlated with intraobserver and interobserver analyses (r=0.94, p<0.001, r=0.82, p<0.001, respectively). UFCT scores for hyperaeration significantly correlated with clinical scores (r=0.75, p<0.01), whereas those for the others did not. UFCT is useful for assessing BPD. Hyperaeration was the most common and reproducible finding, and its extent significantly correlated with clinical severity. (author)

Kubota, Jun; Ohki, Yasushi; Inoue, Tomio; Mochizuki, Hiroyuki; Aoki, Jun; Morikawa, Akihiro; Endo, Keigo [Gunma Univ., Maebashi (Japan). School of Medicine; Sakurai, Minako; Shigeta, Makoto

1998-05-01

31

Anomalous diffusion and long-range correlations in the score evolution of the game of cricket  

Science.gov (United States)

We investigate the time evolution of the scores of the second most popular sport in the world: the game of cricket. By analyzing, event by event, the scores of more than 2000 matches, we point out that the score dynamics is an anomalous diffusive process. Our analysis reveals that the variance of the process is described by a power-law dependence with a superdiffusive exponent, that the scores are statistically self-similar following a universal Gaussian distribution, and that there are long-range correlations in the score evolution. We employ a generalized Langevin equation with a power-law correlated noise that describes all the empirical findings very well. These observations suggest that competition among agents may be a mechanism leading to anomalous diffusion and long-range correlation.

Ribeiro, Haroldo V.; Mukherjee, Satyam; Zeng, Xiao Han T.

2012-08-01

32

Beyond Correlations: Usefulness of High School GPA and Test Scores in Making College Admissions Decisions  

Science.gov (United States)

Correlational evidence suggests that high school GPA is better than admission test scores in predicting first-year college GPA, although test scores have incremental predictive validity. The usefulness of a selection variable in making admission decisions depends in part on its predictive validity, but also on institutions' selectivity and…

Sawyer, Richard

2013-01-01

33

Correlated physical and mental health summary scores for the SF-36 and SF-12 Health Survey, V.1  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background The SF-36 and SF-12 summary scores were derived using an uncorrelated (orthogonal factor solution. We estimate SF-36 and SF-12 summary scores using a correlated (oblique physical and mental health factor model. Methods We administered the SF-36 to 7,093 patients who received medical care from an independent association of 48 physician groups in the western United States. Correlated physical health (PCSc and mental health (MCSc scores were constructed by multiplying each SF-36 scale z-score by its respective scoring coefficient from the obliquely rotated two factor solution. PCSc-12 and MCSc-12 scores were estimated using an approach similar to the one used to derive the original SF-12 summary scores. Results The estimated correlation between SF-36 PCSc and MCSc scores was 0.62. There were far fewer negative factor scoring coefficients for the oblique factor solution compared to the factor scoring coefficients produced by the standard orthogonal factor solution. Similar results were found for PCSc-12, and MCSc-12 summary scores. Conclusion Correlated physical and mental health summary scores for the SF-36 and SF-12 derived from an obliquely rotated factor solution should be used along with the uncorrelated summary scores. The new scoring algorithm can reduce inconsistent results between the SF-36 scale scores and physical and mental health summary scores reported in some prior studies. (Subscripts C = correlated and UC = uncorrelated

Cunningham William E

2007-09-01

34

Attenuation of the Squared Canonical Correlation Coefficient under Varying Estimates of Score Reliability  

Science.gov (United States)

Research pertaining to the distortion of the squared canonical correlation coefficient has traditionally been limited to the effects of sampling error and associated correction formulas. The purpose of this study was to compare the degree of attenuation of the squared canonical correlation coefficient under varying conditions of score reliability.…

Wilson, Celia M.

2010-01-01

35

Correlation between the FINish diabetes risk score and the severity of coronary artery disease  

Directory of Open Access Journals (Sweden)

Full Text Available Background/Aim. The FINish Diabetes RIsk SCore (FINDRISC which includes age, body mass index (BMI, waist circumference, physical (in activity, diet, arterial hypertension, history of high glucose levels, and family history of diabetes, is of a great significance in identifying patients with impaired glucose tolerance and a 10-year risk assessment of developing type 2 diabetes in adults. Due to the fact that the FINDRISC score includes parameters which are risk factors for coronary artery disease (CAD, our aim was to determine a correlation between this score, and some of its parameters respectively, with the severity of angiographically verified CAD in patients with stable angina in two ways: according to the Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX score and the number of diseased coronary arteries. Methods. The study included 70 patients with stable angina consecutively admitted to the Clinic of Cardiology, Military Medical Academy, Belgrade. The FINDRISC score was calculated in all the patients immediately prior to angiography. Venous blood samples were collected and inflammatory markers [erythrocyte sedimentation rate (ESR, leucocytes, C-reactive protein (CRP, total cholesterol, HDL cholesterol, triglycerides and fasting glucose] determined. Coronary angiography was performed in order to determine the severity of coronary artery disease according to the SYNTAX score and the number of affected coronary vessels: 1-vessel, 2-vessel or 3-vessel disease (hemodynamically significant stenoses: more than 70% of the blood vessel lumen. The patients were divided into three groups regarding the FINDRISC score: group I: 5-11 points; group II: 12-16 points; group III: 17-22 points. Results. Out of 70 patients (52 men and 18 women enrolled in this study, 14 had normal coronary angiogram. There was a statistically significant positive correlation between the FINDRISC score and its parameters respectively (age, body mass index-BMI, waist circumference and the severity of CAD according to the SYNTAX score (p < 0.001 and the number of diseased coronary arteries (p < 0.001. The patients with higher FINDRISC score (groups II and III had more severe and extensive CAD according to the SYNTAX score than the group I. The odds ratio with 95% confidence intervals (CI between the group III and the group I was 5.143 (95% CI 1.299-20.360, p = 0.002 and between the group II and the group I 5.867 (95% CI 1.590- 21.525, p = 0.007. There were no differences in odds ratio for multivessel disease according to FINDRISC score between the group II and the group III [1.141; (95% CI 0.348-3.734. In the group I mean SYNTAX score was 5.18, and more than 70% of patients had normal coronary angiogram. In the group II mean SYNTAX score was 17.06, and more than 70% of patients had 2-vessel disease and 3- vessel disease, and in the group III mean SYNTAX score was 18.89, and 2-vessel and 3-vessel disease had 36.36% and 31.82% patients, respectively. In multiple regression analysis, where SYNTAX score was dependent variable, and age, BMI, waist circumference, FINDRISC score were independent variables, we found that only FINDRISC score was independent predictor of SYNTAX score. Conclusion. The obtained results suggest a statistically significant correlation between the FINDRISC score and its parameters (age, BMI, waist circumference and the severity of CAD according to the SYNTAX score and the number of diseased coronary arteries. The FINDRISC score may be useful in identifying patients at the high risk for coronary artery disease.

?uri? Predrag

2014-01-01

36

Correlation of fracture index with BMD T score in postmenopausal females  

International Nuclear Information System (INIS)

Objective: To find the correlation between fracture index and BMD T-score so that fracture index can be used as a predictive tool for fracture risk estimation in post menopausal females. Design: A cross-sectional study was conducted on a sample of 396 women age 50 years and above. BMD T-score measurements using ultrasound and fracture index calculation based on the risk factor assessment were performed. Results: The study results showed that when fracture index increases BMD T-score decreased to osteoporotic range and correlation coefficient is -0.162. Conclusion: When fracture index increases, BMD T-score decreases therefore we can use fracture index as an assessment tool for predicting fracture risk in postmenopausal females. (author)

37

The cost of quality: how VBP scores correlate with hospital costs.  

Science.gov (United States)

A study sought to correlate projected total performance scores (TPSs) for hospitals under the Medicare value-based purchasing (VBP) program with routine costs as reported by each hospital for the corresponding measurement periods. The study focused on routine service costs and common departmental costs because they are generally shared among all hospitals. The study's findings suggest that these costs tend to be higher among hospitals that achieve higher levels of quality as measured by VBP scores. PMID:23088054

Shoemaker, William

2012-10-01

38

MR imaging of acute pancreatitis: Correlation of abdominal wall edema with severity scores  

Energy Technology Data Exchange (ETDEWEB)

Objective: To study MRI findings of abdominal wall edema (AWE) in acute pancreatitis as well as correlations between AWE and the severity of acute pancreatitis according to the MR severity index (MRSI) and the Acute Physiology And Chronic Healthy Evaluation III (APACHE III) scoring system. Materials and methods: A total of 160 patients with AP admitted to our institution between December 2009 and March 2011 were included in this study. MRI was performed within 48 h after admission. MRI findings of acute pancreatitis were noted, including AWE on the MRI. The abdominal wall area was divided into quarters, and each area involved was recorded as 1 point to score the severity of AWE. The severity of acute pancreatitis was studied using both the MRSI and the APACHE III scoring system. Spearman correlation of AWE with the MRSI and the APACHE III scoring system was analyzed. Results: In 160 patients with acute pancreatitis, 53.8% had AWE on MRI. The average AWE score was 1.2 {+-} 1.4 points. The prevalence of AWE was 30.5%, 64.5% and 100% in mild, moderate and severe AP, respectively, according to MRSI. AWE on MRI was correlated with MRSI scores (r = 0.441, p = 0.000). According to APACHE III scores, the averages were 2.0 {+-} 1.1 and 2.6 {+-} 1.1 points in mild AP and severe AP, respectively (P = 0.016). AWE was slightly correlated with the APACHE III scores (r = 0.222, p = 0.005). Conclusion: AWE on MRI in acute pancreatitis is common, which may be a supplementary indicator in determining the severity of AP.

Yang, Ru, E-mail: yangru0904@163.com [Sichuan Key laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China); Jing, Zong Lin, E-mail: jzl325@163.com [Sichuan Key laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China); Zhang, Xiao Ming, E-mail: zhangxm@nsmc.edu.cn [Sichuan Key laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China); Tang, Wei, E-mail: tw-n-g-up@163.com [Sichuan Key laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China); Xiao, Bo, E-mail: xiaoboimaging@163.com [Sichuan Key laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China); Huang, Xiao Hua, E-mail: nc_hxh1966@yahoo.com.cn [Sichuan Key laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China); Yang, Lin, E-mail: llinyangmd@163.com [Sichuan Key laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China); Feng, Zhi Song, E-mail: fengzhisong@medmail.com.cn [Department of Gastroenterology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China)

2012-11-15

39

MR imaging of acute pancreatitis: Correlation of abdominal wall edema with severity scores  

International Nuclear Information System (INIS)

Objective: To study MRI findings of abdominal wall edema (AWE) in acute pancreatitis as well as correlations between AWE and the severity of acute pancreatitis according to the MR severity index (MRSI) and the Acute Physiology And Chronic Healthy Evaluation III (APACHE III) scoring system. Materials and methods: A total of 160 patients with AP admitted to our institution between December 2009 and March 2011 were included in this study. MRI was performed within 48 h after admission. MRI findings of acute pancreatitis were noted, including AWE on the MRI. The abdominal wall area was divided into quarters, and each area involved was recorded as 1 point to score the severity of AWE. The severity of acute pancreatitis was studied using both the MRSI and the APACHE III scoring system. Spearman correlation of AWE with the MRSI and the APACHE III scoring system was analyzed. Results: In 160 patients with acute pancreatitis, 53.8% had AWE on MRI. The average AWE score was 1.2 ± 1.4 points. The prevalence of AWE was 30.5%, 64.5% and 100% in mild, moderate and severe AP, respectively, according to MRSI. AWE on MRI was correlated with MRSI scores (r = 0.441, p = 0.000). According to APACHE III scores, the averages were 2.0 ± 1.1 and 2.6 ± 1.1 points in mild AP and severe AP, respectively (P = 0.016). AWE was slightly correlated with the APACHE III scores (r = 0.222, p = 0.005). Conclusion: AWE on MRI in acute pancreatitis is common, which may be a supplementary indicator in determining the severity of AP.

40

Periprostatic Fat Thickness on MRI: Correlation With Gleason Score in Prostate Cancer.  

Science.gov (United States)

OBJECTIVE. The purpose of this study was to retrospectively evaluate the relationship between periprostatic fat thickness on MRI and Gleason score of prostate cancer using radical prostatectomy as the reference standard. MATERIALS AND METHODS. This study included 190 patients (mean age [± SD], 66.9 ± 7.0 years) who underwent MRI before radical prostatectomy. Two radiologists measured the subcutaneous and periprostatic fat thickness on midsagittal T2-weighted MR images as the shortest perpendicular distance from the pubic symphysis to the skin and prostate, respectively. Subcutaneous and periprostatic fat along with age, height, weight, body mass index, and prostate-specific antigen (PSA) were correlated with Gleason score by using Pearson (r) or Spearman (?) correlation coefficients and compared between low- (Gleason score = 6) and high- (? 7) grade prostate cancer by using univariate and multivariate logistic regression analyses. RESULTS. The mean subcutaneous and periprostatic fat thicknesses were 24.0 ± 8.4 mm and 5.0 ± 2.0 mm, respectively. The Gleason score was significantly correlated with age (? = 0.181, p = 0.012), PSA (? = 0.345, p PSA level, and periprostatic fat thickness (odds ratio, 1.331; 95% CI, 1.063-1.666) were independently predictive of high-grade (p ? 0.013) disease. CONCLUSION. Periprostatic fat thickness on MRI showed a mild to modest but significant correlation with Gleason score of prostate cancer with radical prostatectomy as the reference standard and was an independent predictive factor for high-grade prostate cancer. PMID:25539273

Woo, Sungmin; Cho, Jeong Yeon; Kim, Sang Youn; Kim, Seung Hyup

2015-01-01

41

Clinical Factors Affecting Discrepant Correlation Between Asthma Control Test Score and Pulmonary Function  

Science.gov (United States)

The Asthma Control Test (ACT) score is widely used in asthma clinics, particularly with the recent emphasis on achievement and maintenance of optimal asthma control. However, this self-assessment score does not always correspond with lung function parameters, leading to uncertainty about each patient's control status; therefore, we investigated the clinical characteristics that are associated with discrepant correlation between the ACT score and pulmonary function. The 252 adult asthmatic subjects were divided into 5 groups according to their changes in FEV1% predicted values and ACT scores between 2 consecutive visits three months apart. The data were retrospectively reviewed and several clinical variables were compared. Elderly, non-eosinophilic, non-atopic asthma patients were more likely to show paradoxical changes of pulmonary function and ACT score. Female patients were prone to report exaggerated changes of ACT score compared with baseline lung function and changes in FEV1 levels. This group was using more medications for rhinosinusitis. Male patients seemed less sensitive to changes in lung function. From these findings, we conclude that when assessing asthma control status, physicians should carefully consider patient age, gender, atopy status, blood eosinophil levels, and comorbidities along with their ACT scores and pulmonary function test results. PMID:25553267

Park, So Young; Yoon, Sun-Young; Shin, Bomi; Kwon, Hyouk-Soo; Kim, Tae-Bum; Moon, Hee-Bom

2015-01-01

42

Firing patterns of pallidal cells in parkinsonian patients correlate with their pre-pallidotomy clinical scores.  

Science.gov (United States)

It is unclear how the disordered activity of cells in the basal ganglia contributes to the symptoms of Parkinson's disease (PD). We recorded from single neurons extracellularly in 3 regions of the globus pallidus (GPe, GPie and GPii) in patients undergoing pallidotomy for PD. Movement-related cell firing patterns, analysed using hidden Markov models, were significantly correlated with patients' preoperative clinical scores (off drugs). Responses of cells in GPii correlated best with the scores for specific motor tasks, rather than general ones related to activities of daily living, but the reverse was true for responses from GPe. In both GPii and GPe, a higher score (i.e. greater parkinsonian severity) was associated with greater variability in cell firing rather than an increase in firing rate itself. PMID:11059912

El-Deredy, W; Branston, N M; Samuel, M; Schrag, A; Rothwell, J C; Thomas, D G; Quinn, N P

2000-10-20

43

New Perspectives on the Correlation of SAT Scores, High School Grades, and Socioeconomic Factors  

Science.gov (United States)

In studies of the SAT, correlations of SAT scores, high school grades, and socioeconomic factors (SES) are usually obtained using a university as the unit of analysis. This approach obscures an important structural aspect of the data: The high school grades received by a given institution come from a large number of high schools, all of which have…

Zwick, Rebecca; Greif Green, Jennifer

2007-01-01

44

Score functions and statistical criteria to manage intensive follow up in business surveys  

Directory of Open Access Journals (Sweden)

Full Text Available In the frame of a statistical survey, the identification of non respondent units thatshould be object with priority of a reminder action (Intensive Follow Up - IFU, with the aimto produce enough good estimates, represents a relevant, but quite not deeply analysed methodological aspect. In this context, we propose and compare some score functions -that can be all reconnected to a generalised function – evaluating how much is dangerousthe exclusion from calculations of each unit. Moreover, we evaluate and compare somecriteria aimed at identifying IFU units by means of suitable statistical tests or thresholdsderived by parametric or non parametric methods. A comparative empirical applicationon a panel of Italian retail trade businesses has been carried out and commented.

Roberto Gismondi

2013-05-01

45

Assessment of arthritis in rats with CIA: : Correlation between thermographic measurements and clinical score.  

DEFF Research Database (Denmark)

Thermography is the technique of measuring natural thermal radiation from body tissues of clinical interest. It is safe, requires no control of environmental conditions and non invasive. Our study was designed to evaluate a physiological parameter, joint surface temperature, measured with computerized digital infrared thermal imaging, and its association with stages of clinical scores in a rat collagen induced arthritis model. Arthritis was induced with collagen immunization in eight Lewis rats.  Four of the animals were treated with dexamethasone as a negative control. Disease progression was monitored by paw edema and body weight. On the basis of paw edema a clinical score was given each paw of the animals involved in the study. The mean temperature of a region covering the metatarsal joint was compared with a reference area on the back of the same rat. The temperature ratios were compared with the clinical score. The mean joint temperature increased with increasing clinical severity in the acute stage of the disease and there was a correlation between temperature ratio and clinical scores. Joints were warmer at higher score and lower in normal score.  The preliminary data indicates that thermography may be a potent supplemental clinical parameter in the evaluation of the severity of the arthritis in the acute stage and further investigations are underway to evaluate the thermographic assessment of the disease progress and response to therapeutic intervention.

Jasemian, Yousef

46

MRI bone oedema scores are higher in the arthritis mutilans form of psoriatic arthritis and correlate with high radiographic scores for joint damage  

DEFF Research Database (Denmark)

INTRODUCTION: The aim of this study was to investigate the magnetic resonance imaging (MRI) features of bone disease in the arthritis mutilans (AM) form of psoriatic arthritis (PsA). METHODS: Twenty-eight patients with erosive PsA were enrolled (median disease duration of 14 years). Using x-rays of both hands and feet, 11 patients were classified as AM and 17 as non-AM (erosive psoriatic arthritis without bone lysis)by two observers. MRI scans (1.5T) of the dominant hand (wrist and fingers scanned separately) were obtained using standard contrast-enhanced T1-weighted and fat-saturated T2-weighted sequences. Scans were scored separately by two readers for bone erosion, oedema and proliferation using a PsA MRI scoring system. X-rays were scored for erosions and joint space narrowing. RESULTS: On MRI, 1013 bones were scored by both readers. Reliability for scoring erosions and bone oedema was high (intraclass correlation coefficients = 0.80 and 0.77 respectively) but only fair for bone proliferation (intraclass correlation coefficient = 0.42). MRI erosion scores were higher in AM patients (53.0 versus 15.0, p = 0.004) as were bone oedema and proliferation scores (14.7 versus 10.0, p = 0.056 and 3.6 versus 0.7, p = 0.003 respectively). MRI bone oedema scores correlated with MRI erosion scores and X-ray erosion and joint space narrowing scores (r = 0.65, p = 0.0002 for all) but not the disease activity score 28-C reactive protein (DAS28CRP) or pain scores. CONCLUSIONS: In this patient group with PsA, MRI bone oedema, erosion and proliferation were all more severe in the AM-form. Bone oedema scores did not correlate with disease activity measures but were closely associated with X-ray joint damage scores. These results suggest that MRI bone oedema may be a pre-erosive feature and that bone damage may not be coupled with joint inflammation in PsA.

Tan, Yu M; Østergaard, Mikkel

2009-01-01

47

Correlation between Umbilical Cord pH and Apgar Score in High-Risk Pregnancy  

Directory of Open Access Journals (Sweden)

Full Text Available Objective:The Apgar score as a proven useful tool for rapid assessment of the neonate is often poorly correlated with other indicators of intrapartum neonatal well-being. This study was carried out to determine the correlation between umbilical cord pH and Apgar score in high-risk pregnancies.Methods:This is a prospective cross-sectional, analytic study performed on 96 mother-fetal pairs during 2004-2005 at Shahid Yahyanejad hospital, which is affiliated to Babol University of Medical Sciences. Apgar score at 1 and 5 minutes after birth was taken and an umbilical cord blood gas analysis was done immediately after birth in both groups. Mothers came with a labor pain and were divided into high-risk and low risk if they have had any perinatal risk factors. Other data like gestational age, birth weight, need for resuscitation and admission to the newborn ward or NICU was gathered by a questionnaire for comparison between the two groups. P-value less than 0.05 was considered being significant.Findings:The gestational age and birth weight were the same in high-risk and low risk mothers. Mean umbilical artery blood pH in high-risk mothers was significantly lower than in low risk mothers (P=0.004. Mean Apgar scores at 1 and 5 minutes were significantly lower in high-risk mothers than in low risk mothers (P< 0.05. According to the Kendal correlation coefficient there was no significant correlation between Apgar score at 1 and 5 minutes and umbilical cord pH in low risk group (r=0.212, P=0.1. But in high-risk group there was significant correlation between Apgar score at 1st and 5th minute and the umbilical cord pH (r=0.01, P=0.036 and r=0.176, P=0.146, respectively.Conclusion:Combination of Apgar score and umbilical cord pH measurement in high-risk pregnant mother could better detect jeopardized baby.

Mousa Ahmadpour-Kacho

2010-12-01

48

Correlation Between Umbilical Cord pH and Apgar Score in High-Risk Pregnancy  

Directory of Open Access Journals (Sweden)

Full Text Available Objective:The Apgar score as a proven useful tool for rapid assessment of the neonate is often poorly correlated with other indicators of intrapartum neonatal well-being. This study was carried out to determine the correlation between umbilical cord pH and Apgar score in high-risk pregnancies. Methods:This is a prospective cross-sectional, analytic study performed on 96 mother-fetal pairs during 2004-2005 at Shahid Yahyanejad hospital, which is affiliated to Babol University of Medical Sciences. Apgar score at 1 and 5 minutes after birth was taken and an umbilical cord blood gas analysis was done immediately after birth in both groups. Mothers came with a labor pain and were divided into high-risk and low risk if they have had any perinatal risk factors. Other data like gestational age, birth weight, need for resuscitation and admission to the newborn ward or NICU was gathered by a questionnaire for comparison between the two groups. P-value less than 0.05 was considered being significant. Findings:The gestational age and birth weight were the same in high-risk and low risk mothers. Mean umbilical artery blood pH in high-risk mothers was significantly lower than in low risk mothers (P=0.004. Mean Apgar scores at 1 and 5 minutes were significantly lower in high-risk mothers than in low risk mothers (P<0.05. According to the Kendal correlation coefficient there was no significant correlation between Apgar score at 1 and 5 minutes and umbilical cord pH in low risk group (r=0.212, P=0.1. But in high-risk group there was significant correlation between Apgar score at 1st and 5th minute and the umbilical cord pH (r=0.01, P=0.036 and r=0.176, P=0.146, respectively. Conclusion:Combination of Apgar score and umbilical cord pH measurement in high-risk pregnant mother could better detect jeopardized baby.

Mahmood Hajiahmadi

2010-12-01

49

Massa ventricular e critérios eletrocardiográficos de hipertrofia: avaliação de um novo escore Ventricular mass and electrocardiographic criteria of hypertrophy: evaluation of new score  

Directory of Open Access Journals (Sweden)

Full Text Available FUNDAMENTO: A hipertrofia ventricular esquerda (HVE é um importante e independente fator de risco cardiovascular. Inexistem, no Brasil, estudos desenhados para testar a eficácia do eletrocardiograma (ECG no diagnóstico desse grave processo patológico. OBJETIVO: Avaliar um novo escore eletrocardiográfico para diagnóstico de HVE pelo ECG: soma da maior amplitude da onda S com a maior da onda R no plano horizontal, multiplicando-se o resultado pela duração do QRS [(S+R X QRS] e comparando-o com os critérios eletrocardiográficos clássicos. MÉTODOS: Foram analisados os ecocardiogramas e ECG de 1.204 pacientes hipertensos em tratamento ambulatorial. Avaliou-se o índice de massa do ventrículo esquerdo (IMVE pelo ecocardiograma, firmando-se o diagnóstico de HVE quando > 96 g/m² para mulheres e > 116 g/m² para homens. No ECG analisaram-se quatro critérios clássicos de HVE, além do novo escore a ser testado. RESULTADOS: Todos os índices estudados tiveram correlação estatisticamente significativa com a massa calculada do ventrículo esquerdo (VE. Porém, o novo escore foi o que apresentou maior correlação (r = 0,564. Os outros critérios apresentaram as seguintes correlações: Romhilt-Estes (r = 0,464; Sokolow-Lyon (r = 0,419; Cornell voltagem (r = 0,377; Cornell duração (r = 0,444. Para avaliação da acurácia do índice testado, utilizou-se o ponto de corte de 2,80 mm.s. Com esse valor foram obtidas as seguintes cifras para sensibilidade e especificidade: 35,2% e 88,7%, respectivamente. CONCLUSÃO: Todos os critérios eletrocardiográficos para avaliação da massa do VE apresentaram baixa sensibilidade. O novo escore foi o que apresentou melhor correlação com o IMVE em relação aos outros avaliados.BACKGROUND: The left ventricular hypertrophy (LVH is an important and independent cardiovascular risk factor. There is a scarcity of studies in Brazil designed to test the efficacy of the electrocardiogram (ECG in the diagnosis of this important pathological process. OBJECTIVE: To evaluate a new electrocardiographic score for the diagnosis of LVH by ECG: the sum of the highest amplitude of the S wave and the highest amplitude of the R wave on the horizontal plane, multiplied by the result of the QRS duration [(S+R X QRS] and comparing it with the classic electrocardiographic criteria. METHODS: The echocardiograms and ECG of 1,204 hypertensive patients receiving outpatient care were evaluated. The left ventricular mass index (LVMI was assessed by the echocardiogram, with a diagnosis of LVH when the LVMI was > 96 g/m² for women and > 116 g/m² for men. Four classic criteria of LVH were analyzed at the ECG, in addition to the new score to be tested. RESULTS: In general, the studied ECG-LVH criteria showed significant statistical correlation to the echocardiographic LVMI. The (R+S X QRS index, using 2.80 mm.s as the cutoff value, provided test accuracy regarding sensibility and specificity of 35.2% and 88.71%, respectively, representing the best correlation to LVMI (r=0.564 when compared to the other indexes: Romhilt-Estes (r=0.464; Sokolow-Lyon (r=0.419; Cornell voltage (r=0.377; Cornell product r=0.444. CONCLUSION: All the electrocardiographic criteria used for the assessment of the LV mass presented low sensitivity. The new score presented the best correlation with LVMI when compared to the other indexes.

Cléber do Lago Mazzaro

2008-04-01

50

Massa ventricular e critérios eletrocardiográficos de hipertrofia: avaliação de um novo escore / Ventricular mass and electrocardiographic criteria of hypertrophy: evaluation of new score  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese FUNDAMENTO: A hipertrofia ventricular esquerda (HVE) é um importante e independente fator de risco cardiovascular. Inexistem, no Brasil, estudos desenhados para testar a eficácia do eletrocardiograma (ECG) no diagnóstico desse grave processo patológico. OBJETIVO: Avaliar um novo escore eletrocardiog [...] ráfico para diagnóstico de HVE pelo ECG: soma da maior amplitude da onda S com a maior da onda R no plano horizontal, multiplicando-se o resultado pela duração do QRS [(S+R) X QRS)] e comparando-o com os critérios eletrocardiográficos clássicos. MÉTODOS: Foram analisados os ecocardiogramas e ECG de 1.204 pacientes hipertensos em tratamento ambulatorial. Avaliou-se o índice de massa do ventrículo esquerdo (IMVE) pelo ecocardiograma, firmando-se o diagnóstico de HVE quando > 96 g/m² para mulheres e > 116 g/m² para homens. No ECG analisaram-se quatro critérios clássicos de HVE, além do novo escore a ser testado. RESULTADOS: Todos os índices estudados tiveram correlação estatisticamente significativa com a massa calculada do ventrículo esquerdo (VE). Porém, o novo escore foi o que apresentou maior correlação (r = 0,564). Os outros critérios apresentaram as seguintes correlações: Romhilt-Estes (r = 0,464); Sokolow-Lyon (r = 0,419); Cornell voltagem (r = 0,377); Cornell duração (r = 0,444). Para avaliação da acurácia do índice testado, utilizou-se o ponto de corte de 2,80 mm.s. Com esse valor foram obtidas as seguintes cifras para sensibilidade e especificidade: 35,2% e 88,7%, respectivamente. CONCLUSÃO: Todos os critérios eletrocardiográficos para avaliação da massa do VE apresentaram baixa sensibilidade. O novo escore foi o que apresentou melhor correlação com o IMVE em relação aos outros avaliados. Abstract in english BACKGROUND: The left ventricular hypertrophy (LVH) is an important and independent cardiovascular risk factor. There is a scarcity of studies in Brazil designed to test the efficacy of the electrocardiogram (ECG) in the diagnosis of this important pathological process. OBJECTIVE: To evaluate a new e [...] lectrocardiographic score for the diagnosis of LVH by ECG: the sum of the highest amplitude of the S wave and the highest amplitude of the R wave on the horizontal plane, multiplied by the result of the QRS duration [(S+R) X QRS)] and comparing it with the classic electrocardiographic criteria. METHODS: The echocardiograms and ECG of 1,204 hypertensive patients receiving outpatient care were evaluated. The left ventricular mass index (LVMI) was assessed by the echocardiogram, with a diagnosis of LVH when the LVMI was > 96 g/m² for women and > 116 g/m² for men. Four classic criteria of LVH were analyzed at the ECG, in addition to the new score to be tested. RESULTS: In general, the studied ECG-LVH criteria showed significant statistical correlation to the echocardiographic LVMI. The (R+S) X QRS index, using 2.80 mm.s as the cutoff value, provided test accuracy regarding sensibility and specificity of 35.2% and 88.71%, respectively, representing the best correlation to LVMI (r=0.564) when compared to the other indexes: Romhilt-Estes (r=0.464); Sokolow-Lyon (r=0.419); Cornell voltage (r=0.377); Cornell product r=0.444). CONCLUSION: All the electrocardiographic criteria used for the assessment of the LV mass presented low sensitivity. The new score presented the best correlation with LVMI when compared to the other indexes.

Cléber do Lago, Mazzaro; Francisco de Assis, Costa; Maria Teresa Nogueira, Bombig; Bráulio, Luna Filho; Ângelo Amato Vincenzo de, Paola; Antonio Carlos de Camargo, Carvalho; William da, Costa; Francisco Antonio Helfenstein, Fonseca; Rui Manoel dos Santos, Póvoa.

2008-04-01

51

Correlation between psychometric test scores and learning tying of surgical reef knots.  

OpenAIRE

We have investigated the correlation between the scores attained on a computerised psychometric test, measuring psychomotor aptitude and learning tying of a surgical reef knot. Fifteen surgical trainees performed a test of psychomotor aptitude (ADTRACK 2) from the MICROPAT testing system. They then performed a simple test of their ability to tie a surgical reef knot and were assessed by a panel of experts prior to embarking on a standardised course of instruction and practice session. The kno...

Dashfield, A. K.; Lambert, A. W.; Campbell, J. K.; Wilkins, D. C.

2001-01-01

52

Evaluation of cytogenetic damage in workers exposed to microwave radiation of GEM radar using new criteria in scoring micronucleus test  

International Nuclear Information System (INIS)

The cytokinesis-block micronucleus assay is one of the standard cytogenetic tools employed in the assessment of chromosomal damage subsequent to the exposure to genotoxic/cytotoxic agents on human cells. Within the frame of this study, the cytokinesis-block micronucleus assay was used to assess the baseline cytogenetic damage in binuclear lymphocytes in workers occupationally exposed to microwave radiation of GEM radar by virtue of measuring the frequency of micronuclei, nucleoplasmic bridges and nuclear buds. Microwave radiation of GEM radar equipment acts within microwave field of 10 ?W/cm2 to 10 mW/cm2 and frequency range of 1.5 GHz to 10.9 GHz that has contradictory cytogenetic effect on human cells and DNA molecule. For that reason we used new criteria in scoring micronucleus assay that allows us to measure nucleoplasmic bridges and nuclear buds in addition to micronucleus frequency for more accurate effect on possible damage on the level of the cells. Parameters of the micronucleus test were studied in workers occupationally exposed to microwave radiation of GEM radar and in corresponding unexposed control subjects. It was found that in the subjects who were occupationally exposed to microwave radiation, the levels of micronuclei increased and showed interindividual variations. In addition, new parameters that were measured; nucleoplasmic bridges and nuclear buds, were detected in exposed group in compare to control group that did not showompare to control group that did not shown this type of damage. Differences between mean group values were statistically significant (P<0.05). Our study indicates that micronucleus assay is a very useful tool in the assessment of cytogenetic damage of individuals exposed to microwave radiation of GEM radar equipment. On the basis of the micronucleus frequency and frequencies of nucleoplasmic bridges and nuclear buds, the micronucleus technique with an easy and short-term application and with an easy scoring can be used for detection of damage induced by this type of radiation. (author)

53

Correlations of visual scores, carcass traits, feed efficiency and retail product yield in Nellore cattle  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in english The growing use of visual scores (VS) and ultrasound (US) for carcass evaluation in breeding programs, calls for a knowledge of the relationships between these traits and other relevant characteristics, such as feed efficiency and production of commercial cuts. The objective of this study was to eva [...] luate correlations between body visual scores and carcass traits identified by ultrasound (US) and feed efficiency (FE), carcass weight (HCW), dressing percentage (DP) and retail product yield (RPY) in beef cattle. Nellore cattle (male), 42 non-castrated [NCAST] and 44 castrated [CAST]) were evaluated by both VS and US, at the postweaning (15-month old) and finishing phases (21-month old). Visual scores of conformation (C), precocity (P) and muscling (M) were assessed and the backfat thickness (UBFT), rump fat thickness (URFT) and ribeye area (UREA) were measured by ultrasound. Gain-to-feed (G:F) ratio and residual feed intake (RFI) were measured in feedlot. Hot carcass weight, DP and RPY were determined at harvest. Non-castrated cattle had greater HCW and RPY but lower UBFT and URFT than CAST. Postweaning VS and US were poorly correlated with FE in both sexual conditions. Finishing VS were negatively correlated with G:F in CAST and finishing URFT was negatively correlated with RPY in NCAST. The relationship of VS and US with feed efficiency and meat yield is affected by age at the date of evaluation and by castration. Feed efficiency is not related to the yield of meat cuts in Nellore cattle

Paulo Henrique, Cancian; Rodrigo da Costa, Gomes; Fernando Ricardo, Manicardi; Andrea Cristina, Ianni; Marina de Nadai, Bonin; Paulo Roberto, Leme; Saulo da Luz e, Silva.

2014-02-01

54

Correlation of high-molecular cytokeratin in tissue of prostatic cancer with gleason score and PSA  

Directory of Open Access Journals (Sweden)

Full Text Available The absence of basal cell layer of prostatic acini containing high-molecular cytokeratin, which is immunohistochemically detected by monoclonal antibody 34?E12, is an essential diagnostic characteristic of prostatic cancer. The absence of im munohistochemical reaction in 3 or more pseudo glandular structures of prostatic tissue indicates malignant process. The percentage of immunohistochemically completely negative glandular structures was determined by semiquantitative measurement in tissue specimens obtained by TRUS biopsy of the prostate, and it was correlated with serum PSA concentration and Gleason score. The increase of percentage of glandular prostatic formations completely negative to high-molecular cytokeratin detected by 34?E12 led to simultaneous rise of mean value of Gleason prostatic cancer score (p<0.001 as well as the average serum PSA concentration in subjects (p<0.05.

Markovi?-Lipkovski J.

2005-01-01

55

Correlacao do EuroSCORE com o surgimento de lesao renal aguda pos-operatoria em cirurgia cardiaca / Correlation of the EuroSCORE with the onset of postoperative acute kidney injury in cardiac surgery  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese OBJETIVO: Verificar se há correlação entre valores do EuroSCORE e o risco de desenvolver lesão renal aguda em pacientes submetidos à cirurgia cardíaca. MÉTODOS: Estudo retrospectivo, realizado em hospital terciário, em pacientes consecutivos com indicação para abordagem cirúrgica cardíaca (val [...] vares, isquêmicas e congênitas) entre outubro de 2010 a julho de 2011. RESULTADOS: Foram avaliados cem pacientes. Destes, seis foram excluídos (cinco por doença renal ou terapia dialítica prévias e um devido a informações incompletas no prontuário médico). As principais indicações cirúrgicas foram revascularização miocárdica em 55 pacientes (58,5% dos casos) e trocas valvares em 28 pacientes (29,8%). Conforme o EuroSCORE, 55 pacientes foram classificados como risco alto (58,5%), 27 pacientes como risco médio (28,7%) e 12 pacientes como risco baixo (12,8%). No período pós-operatório, 31 pacientes (33%) evoluíram com aumento da creatinina sérica (18 (19,1%) RIFLE "R"; 7 (7,4%) RIFLE "I"; e 6 (6,5%) RIFLE "F"). Na amostra considerada de alto risco pelos critérios do EuroSCORE, 24 pacientes (43,6%) apresentaram comprometimento renal agudo. Nos pacientes classificados como de médio e de baixo risco, ocorreu lesão renal aguda em 18,5 e 16,6% dos casos, respectivamente. A associação entre a estratificação de risco (baixo, médio e alto) do EuroSCORE e o escore do RIFLE pós-operatório foi estatisticamente significante (p=0,03). CONCLUSÃO: Na população estudada, houve correlação estatisticamente significante entre o EuroSCORE e o risco de desenvolvimento de lesão renal aguda no pós-operatório de cirurgia cardíaca. Abstract in english OBJECTIVE: The objective of this study was to assess the correlation between the European System for Cardiac Operative Risk Evaluation (EuroSCORE) score and the risk of developing acute kidney injury in cardiac surgery patients. METHODS: This retrospective study was conducted at a tertiary hos [...] pital on consecutive cardiac surgery patients (e.g., valvular, ischemic and congenital heart diseases) between October 2010 and July 2011. RESULTS: One hundred patients were assessed. Among the 100 patients, six were excluded, including five because of prior kidney disease or dialysis therapy and one because of incomplete medical records. The primary surgical indications were myocardial revascularization in 55 patients (58.5% of cases) and valve replacement in 28 patients (29.8%). According to the EuroSCORE, 55 patients were classified as high risk (58.5%), 27 patients as medium risk (28.7%) and 12 patients as low risk (12.8%). In the postoperative period, patients were classified with the Risk, Injury, Failure, Loss and End-stage kidney disease (RIFLE) score. Among the 31 patients (33%) who displayed an increase in serum creatinine, 18 patients (19.1%) were classified as RIFLE "R" (risk), seven patients (7.4%) were classified as RIFLE "I" (injury) and six patients (6.5%) were classified as RIFLE "F" (failure). Among the patients who were considered to be high risk according to the EuroSCORE criteria, 24 patients (43.6%) showed acute kidney injury. Among the patients who were classified as medium or low risk, acute kidney injury occurred in 18.5 and 16.6% of the cases, respectively. The correlations between risk stratification (low, medium and high) and the EuroSCORE and postoperative RIFLE scores were statistically significant (p=0.03). CONCLUSION: In the studied population, there was a statistically significant correlation between the EuroSCORE and the risk of developing acute kidney injury in the postoperative period after cardiac surgery.

Edmilson Bastos de, Moura; Saint-Clair Gomes, Bernardes Neto; Fabio Ferreira, Amorim; Renato Camargo, Viscardi.

2013-09-01

56

Correlation of a quantitative videocapillaroscopic score with the development of digital skin ulcers in scleroderma patients  

Directory of Open Access Journals (Sweden)

Full Text Available Background: Systemic sclerosis (SSc is an autoimmune disease characterized by fibrosis of the skin and visceral organs. The microangiopathy is early detectable in the course of the disease by nailfold videocapillaroscopy (NVC, a non-invasive technique with a high diagnostic value. Objective: Aim of our study was to evaluate the feasibility of a quantitative score and its correlation with the digital skin ulcers, which frequently complicate SSc microangiopathy. Methods: We retrospectively analysed the NVC of 65 SSc patients, performed by 200x videocapillaroscopy connected to image analyse software (Videocap; DS MediGroup, Milan, Italy. The analysis of NVC images included: total number of capillaries in the distal row (N, maximum diameter (D and number of giant capillaries (M, M/N ratio and percentage of M, presence/absence of micro-haemorrhages and tortuosity. Results: 21/65 SSc patients experienced digital ulcers within three months after the NVC examination. The N, D, M/N, and percentage of M significantly correlated with the appearance of ischemic ulcers. A multiple regression analysis showed a statistically significant correlation for N, M/N and D, while sensitivity and specificity of these parameters were unsatisfactory. A capillaroscopic score, according to the formula D·M/N2, showed a high specificity and sensibility (93.2% and 85.7% respectively; area under ROC curve: 0.918 to predict the appearance of digital ulcers. Conclusions: This capillaroscopic score may represent a feasible and simple tool in SSc patients’ assessment. The routinely use of this parameter might permit to recognize and to preventively treat SSc patients at high risk to develop digital ulcers.

A. Antonelli

2011-09-01

57

Validity of the Oral Behaviours Checklist: correlations between OBC scores and intensity of facial pain.  

Science.gov (United States)

The first purpose of this study was to translate the Oral Behaviours Checklist (OBC) into Dutch and to examine its psychometric properties. The second purpose was to examine the correlations between scores on the OBC and facial pain, while controlling for the possible confounding effects of psychosocial factors, such as stress, depression, somatisation and anxiety. The OBC was translated, following the international RDC/TMD consortium guidelines. Its psychometric properties were examined by assessing the test-retest reliability and concurrent validity [correlations between the OBC and the previously developed Oral Parafunctions Questionnaire (OPQ)]. Participants were 155 patients with TMD (77% female; mean age and s.d. = 43.6 and 14.4 years). The translation of the OBC into Dutch proceeded satisfactorily. The psychometric properties of the Dutch OBC were good; test-retest reliability was excellent (ICC = 0.86, P OBC and OPQ was high (r = 0.757, P < 0.001), while the correlations between individual items ranged from 0.389 to 0.892 (P < 0.001). Similar to previous Dutch studies using the OPQ, no significant correlation was found between oral parafunctions and facial pain (r = 0.069, P = 0.892). No significant correlations could be found between oral parafunctional behaviours and facial pain. PMID:24274580

van der Meulen, M J; Lobbezoo, F; Aartman, I H A; Naeije, M

2014-02-01

58

High correlation between net promoter score and the development of consumers' willingness to pay (Empirical evidence from European mobile markets)  

OpenAIRE

This paper shows that the correlation between the Net Promoter Score and consumers' Willingness To Pay in five European mobile markets is very strong. The Net Promoter Score is provided by a survey and the Willingness To Pay is calculated using the Spokes Model which is an economic model based on horizontal differentiation among firms. The model input data (firms' revenues, number of subscribers and profits) are provided by Merill Lynch, Bank of America. The well-known correlation between Net...

Jeanjean, Franc?ois

2011-01-01

59

National Institutes of Health (NIH) Chronic GVHD Staging in Severely Affected Patients: Organ and Global Scoring Correlate with Established Indicators of Disease Severity and Prognosis  

Science.gov (United States)

Between 2004 and 2010, 189 adult patients were enrolled on the National Cancer Institute (NCI) cross-sectional chronic Graft-versus-Host disease (cGVHD) natural history study. Patients were evaluated by multiple disease scales and outcome measures including the 2005 NIH Consensus Project cGVHD severity score. The purpose of this study is to assess the validity of the NIH scoring variables as determinants of disease severity in severely affected patients in order to standardize clinician evaluation and staging of cGVHD. 125 of 189 patients met criteria for severe cGVHD on the NIH global score and 62 had moderate disease, with a median of 4 (range 1–8) involved organs. Clinician average NIH organ score and the corresponding organ scores performed by subspecialists were highly correlated (r=0.64). NIH global severity scores showed significant associations with nearly all functional and quality of life outcome measures including Lee Scale, SF-36 Physical Component Scale (PCS), 2 minutes walk, grip strength, range of motion and Human Activity Profile (HAP). Joints/fascia, skin, and lung involvement impacted function and quality of life most significantly and showed highest number of correlations with outcome measures. The final Cox model showing factors jointly predictive for survival contained the time from cGVHD diagnosis (>49 vs. ?49 months, HR=0.23; p=0.0011), absolute eosinophil count of (0–0.5 vs. >0.5 cells/µL, HR=3.95; p=0.0006) at the time of NIH evaluation, and NIH lung score (3 vs. 0–2, HR=11.02; p <0.0001). These results demonstrate that NIH organs and global severity scores are reliable measures of cGVHD disease burden. Strong association with subspecialist evaluation suggests that NIH organs and global severity scores are appropriate for clinical and research assessments, and may serve as a surrogate for more complex sub-specialist exams. In this population of severely affected patients, NIH lung score is the strongest predictor of poor overall survival, both alone and after adjustment for other important factors. PMID:23340040

Baird, K.; Steinberg, S.M.; Grkovic, L.; Pulanic, D.; Cowen, E.W.; Mitchell, S.A.; Williams, K.M.; Datiles, M.B.; Bishop, R.; Bassim, C.W.; Mays, J.W.; Edwards, D.; Cole, K.; Avila, D.N.; Taylor, T.; Urban, A.; Joe, G.O.; Comis, L.E.; Berger, A.; Stratton, P.; Zhang, D.; Shelhamer, J.H.; Gea-Banacloche, J.C.; Sportes, C.; Fowler, D.H.; Gress, R.E.; Pavletic, S.Z.

2013-01-01

60

Correlations among scores on the Matrix Analogies Test--Short Form and the WISC--R with gifted youth.  

Science.gov (United States)

A study of the correlations between scores on the Matrix Analogies Test--Short Form and the WISC--R was conducted with 39 students enrolled in a Saturday program for the intellectually gifted. The Matrix Analogies Test was group-administered and WISC--R scores were obtained from records required for entry into the program. A significant Pearson r of .52 was found between the Matrix Analogies scores and the Performance IQs of the WISC--R; other correlations were not significant. PMID:8058884

Karnes, F A; McGinnis, J C

1994-06-01

61

Correlación entre score de calcio coronario, esteatosis hepática y síndrome metabólico / Correlation between coronary calcium score, hepatic steatosis and metabolic syndrome  

Scientific Electronic Library Online (English)

Full Text Available SciELO Chile | Language: Spanish Abstract in spanish Objetivos. Demostrar la correlación que existe entre presencia o no de enfermedad coronaria establecida (medida a través del índice de Agatston) y esteatosis hepática en los segmentos visualizados del hígado al momento de realizar el score de calcio. Material y Métodos. Estudio retrospectivo que inc [...] luyó 229 pacientes con factores de riesgo para enfermedad coronaria a los que se les realizó tomografía computada multicorte de arterias coronarias o score de calcio. Se evaluó la presencia de enfermedad ateromatosa en arterias coronarias y aorta torácica y atenuación hepática en los segmentos visualizados del hígado. El análisis estadístico incluyó modelos de regresión lineal, estudio por asociación de múltiples variables y modelo CART. Resultados. 229 pacientes, 78% de sexo masculino y 22% femenino, con edad promedio 56 años. Se demostró asociación estadísticamente significativa entre mayor nivel de score de calcio y menor atenuación hepática, en pacientes de mayor edad y sexo masculino. Se logró definir dos tipos de pacientes con score de calcio elevado, un grupo con hipertensión arterial - esteatosis hepática y otro grupo con hipertensión arterial y diabetes tipo 2; los pacientes solamente obesos no tenían mayores niveles de score de calcio. Conclusiones. Existe asociación entre ateromatosis calcificada y esteatosis hepática. Los pacientes con esteatosis hepática como parte de un síndrome metabólico, tienen mayor riesgo de ateroesclerosis. Puede ser útil incorporar la evaluación de esteatosis hepática en la estratificación de riesgo cardiovascular. Abstract in english Objectives. To demonstrate the correlation between the presence or absence of established coronary disease (as measured by the Agatston index) and hepatic steatosis visualized in liver segments when calculating calcium score. Material and Methods. Retrospective study that included229 patients with r [...] isk factors for coronary disease who underwent multislice computed tomography of coronary arteries or calcium score. We evaluated the presence of atherosclerotic disease in coronary arteries and thoracic aorta and liver attenuation in visualized liver segments. Statistical analysis included linear regression models, association studies of multiple variables and CARTmodel. Results. 229 patients, 78% male, average age 56 years. It values statistically significant association was found between higher levels of calcium score and lower hepatic attenuation in older patients and males. We were to define two types of patients with high calcium score, a group with hypertension - hepatic steatosis and another groups with hypertension and type 2 diabetes; patients that were only obese did not have higher levels of calcium score. Conclusions. A relationship exists between calcified atheromatosis disease and hepatics steatosis. Patients with hepatics steatosis as part of a metabolic syndrome are at increased risk of atherosclerosis. It may be useful to incorporate the assessment of hepatics steatosis in cardiovascular risk stratification.

Karina, Hermosilla M; Daniela, Pivcevic C; Julia, Alegria B; Claudio, Silva F.

62

A method for calcium quantification by means of CT coronary angiography using 64-multidetector CT: very high correlation with agatston and volume scores  

International Nuclear Information System (INIS)

To find out whether calcium scoring of the coronary arteries (CAC scoring) could be carried out with a CT angiography of the coronary arteries (CTCA) in a single CT data acquisition. The Agatston and V130 scores for 113 patients were assessed. A calcium volume score (V600 score) was compiled from the CTCA data sets. Intra- and interobserver correlations were excellent (? > 0.97). The intra- and interobserver repeatability coefficients were extremely low, increasing in magnitude from the V600 score to the V130 and Agatston scores. The V600 score underestimates the coronary calcium burden. However, it has a linear relation to the Agatston and V130 scores. Thus, they are predictable from the values of the V600 score. The V600 score shows a linear relation to the classic CAC scores. Due to its extremely high reliability, the score may be a feasible alternative for classic CAC scoring methods in order to reduce radiation dosages. (orig.)

63

Clinical Criteria for Airway Assessment: Correlations with Laryngoscopy and Endotracheal Intubation Conditions  

Directory of Open Access Journals (Sweden)

Full Text Available Difficult intubation, inadequate ventilation and esophageal intubation are the principal causes of death or brain damage related to airway manipulation. The objective of this cross-sectional study was to correlate a preanesthetic evaluation that may be capable of predicting a difficult intubation with the conditions encountered at laryngoscopy and endotracheal intubation. Eighty-one patients submitted to general anesthesia were evaluated at a preanesthetic consultation according to the modified Mallampati classification, the Wilson score and the American Society of Anesthesiologists (ASA difficult airway algorithm. Findings were then correlated with the Cormack-Lehane classification and with the number of attempts at endotracheal intubation. No statistically significant correlations were found between the patients’ Mallampati classification and their Cormack-Lehane grade or between the Mallampati classification and the number of attempts required to achieve endotracheal intubation. Laryngoscopy proved difficult in four patients and in all of these cases the Wilson score had been indicative of a possibly difficult airway, highlighting its good predicting sensitivity. However, the specificity of this test was low, since another 24 patients had the same Wilson score but were classified as Cormack-Lehane I/II. Moreover, two patients who had a Wilson score ? 4 were also classified as Cormack-Lehane grade I/II. The study concluded that the Wilson score, although seldom used in clinical practice, is a highly sensitive predictor of a difficult airway; its specificity, however, is low.

Gustavo Henrique S. Wanderley

2013-08-01

64

A new scoring system in cancer genetics: application to criteria for BRCA1 and BRCA2 mutation screening.  

OpenAIRE

BACKGROUND: In hereditary forms of cancer due to mutations of genes such as BRCA1 and BRCA2, methods have been proposed to predict the presence of a mutation in a family. METHODS: Relying on carriage probability computation is the most predictive, but scores are a good proxy and avoid using computer software. An empirical method, the Manchester scoring system, has been elaborated for BRCA1 and BRCA2 mutation identification. We propose a general scoring system based on a transformation of the ...

Bonai?ti, Bernard; Alarcon, Flora; Andrieu, Nadine; Bonadona, Vale?rie; Dondon, Marie-gabrielle; Pennec, Sophie; Stoppa-lyonnet, Dominique; Bonai?ti-pellie?, Catherine; Perdry, Herve?

2013-01-01

65

Big Macs and Eigenfactor Scores: Don't Let Correlation Coefficients Fool You  

CERN Document Server

The Eigenfactor Metrics provide an alternative way of evaluating scholarly journals based on an iterative ranking procedure analogous to Google's PageRank algorithm. These metrics have recently been adopted by Thomson-Reuters and are listed alongside the Impact Factor in the Journal Citation Reports. But do these metrics differ sufficiently so as to be a useful addition to the bibliometric toolbox? Davis (2008) has argued otherwise, based on his finding of a 0.95 correlation coefficient between Eigenfactor score and total citations for a sample of journals in the field of medicine. This conclusion is mistaken; here we illustrate the basic statistical fallacy to which Davis succumbed. We provide a complete analysis of the 2006 Journal Citation Reports and demonstrate that there are important differences between the information provided by the Eigenfactor Metrics and that provided by Impact Factor and Total Citations.

West, Jevin; Bergstrom, Carl

2009-01-01

66

Modified Chrispin-Norman chest radiography score for cystic fibrosis: observer agreement and correlation with lung function  

Energy Technology Data Exchange (ETDEWEB)

To test observer agreement and two strategies for possible improvement (consensus meeting and reference images) for the modified Chrispin-Norman score for children with cystic fibrosis (CF). Before and after a consensus meeting and after developing reference images three observers scored sets of 25 chest radiographs from children with CF. Observer agreement was tested for line, ring, mottled and large soft shadows, for overinflation and for the composite modified Chrispin-Norman score. Correlation with lung function was assessed. Before the consensus meeting agreement between observers 1 and 2 was moderate-good, but with observer 3 agreement was poor-fair. Scores correlated significantly with spirometry for observers 1 and 2 (-0.72correlation with lung function, but agreement for the modified Chrispin-Norman score did not improve further. Consensus meetings and reference images improve among-observer agreement for the modified Chrispin-Norman score, but good agreement was not achieved among all observers for the modified Chrispin-Norman score and for bronchial line and ring shadows. (orig.)

Jong, P.A. de; Achterberg, J.A.; Kessels, O.A.M.; Beek, F.J. [Department of Radiology, University Medical Center Utrecht, Wilhelmina Children' s Hospital, Utrecht (Netherlands); Ginneken, B. van; Hogeweg, L. [Radboud University Nijmegen Medical Centre, Department of Radiology, Nijmegen (Netherlands); Image Sciences Institute, University Medical Center Utrecht, Utrecht (Netherlands); Terheggen-Lagro, S.W.J. [University Medical Center Utrecht, Wilhelmina Children' s Hospital, Department of Pediatric Pulmonology, Utrecht (Netherlands)

2011-04-15

67

Modified Chrispin-Norman chest radiography score for cystic fibrosis: observer agreement and correlation with lung function  

International Nuclear Information System (INIS)

To test observer agreement and two strategies for possible improvement (consensus meeting and reference images) for the modified Chrispin-Norman score for children with cystic fibrosis (CF). Before and after a consensus meeting and after developing reference images three observers scored sets of 25 chest radiographs from children with CF. Observer agreement was tested for line, ring, mottled and large soft shadows, for overinflation and for the composite modified Chrispin-Norman score. Correlation with lung function was assessed. Before the consensus meeting agreement between observers 1 and 2 was moderate-good, but with observer 3 agreement was poor-fair. Scores correlated significantly with spirometry for observers 1 and 2 (-0.72< R<-0.42, P < 0.05), but not for observer 3. Agreement with observer 3 improved after the consensus meeting. Reference images improved agreement for overinflation and mottled and large shadows and correlation with lung function, but agreement for the modified Chrispin-Norman score did not improve further. Consensus meetings and reference images improve among-observer agreement for the modified Chrispin-Norman score, but good agreement was not achieved among all observers for the modified Chrispin-Norman score and for bronchial line and ring shadows. (orig.)

68

Correlation between Body Condition Score, Blood Biochemical Metabolites, Milk Yield and Quality in Algerian Montbéliarde Cattle  

Directory of Open Access Journals (Sweden)

Full Text Available This study aimed to investigate the correlation between body condition score (BCS, blood biochemical metabolites, milk yield (MY and quality (Mfat in Montbéliarde cattle (31 cows reared in 5 farms of Algerian semi arid area. The BCS was measured in dry and peak of lactation (6 weeks after calving. Blood samples were taken at the time of body condition (BC measurement for determination of energy (Glucose, cholesterol, triglycerides and B-Hydroxybutyrate, nitrogen (urea and albumin and mineral (calcium metabolites. Milk yield was recorded in the 6th week of lactation (peak. A sample of milk for each cow was used to determinate milk fat, density and acidity. The results showed a significant decrease in postpartum BCS accompanied by an increase in cholesterol and B-Hydroxybutyrate (BHB concentration. The correlation analysis showed that BHB concentration in pre calving was negatively correlated with BCS (r=-0.321; P<0.05 and cholesterol (r=-0.308; P<0.05. In postpartum, BCS was negatively correlated with cholesterol (r=-0.416; P<0.05, urea (r=-0.366; P<0.05 and BHB (r=-0.487; P<0.05. However, the level of milk production decreased significantly with high glucose (r=-0.449; P<0.05 and BHB (r=-0.514; P<0.05. The fat content increased significantly with blood triglycerides (r=0.681; P<0.05 and BHB (r=0.522; P<0.05 concentration, indicating a high mobilization of body reserves used for the synthesis of milk fat. In conclusion, it can be assumed that the rate of BHB seems to be the best indicator of the nutritional status of dairy cows that determines their production level and quality.

Charef-Eddine Mouffok1,2,*, Toufik Madani1,2, Lounis Semara1, Nadhira Ayache1 and Amina Rahal1

2013-04-01

69

Anomalous Diffusion and Long-range Correlations in the Score Evolution of the Game of Cricket  

OpenAIRE

We investigate the time evolution of the scores of the second most popular sport in world: the game of cricket. By analyzing the scores event-by-event of more than two thousand matches, we point out that the score dynamics is an anomalous diffusive process. Our analysis reveals that the variance of the process is described by a power-law dependence with a super-diffusive exponent, that the scores are statistically self-similar following a universal Gaussian distribution, and...

Ribeiro, H. V.; Mukherjee, Satyam; Zeng, Xiao Han T.

2012-01-01

70

Impact of white matter hyperintensities scoring method on correlations with clinical data: the LADIS study  

DEFF Research Database (Denmark)

BACKGROUND AND PURPOSE: White matter hyperintensities (WMH) are associated with decline in cognition, gait, mood, and urinary continence. Associations may depend on the method used for measuring WMH. We investigated the ability of different WMH scoring methods to detect differences in WMH load between groups with and without symptoms. METHODS: We used data of 618 independently living elderly with WMH collected in the Leukoaraiosis And DISability (LADIS) study. Subjects with and without symptoms of depression, gait disturbances, urinary incontinence, and memory decline were compared with respect to WMH load measured qualitatively using 3 widely used visual rating scales (Fazekas, Scheltens, and Age-Related White Matter Changes scales) and quantitatively with a semiautomated volumetric technique and an automatic lesion count. Statistical significance between groups was assessed with the chi2 and Mann-Whitney tests. In addition, the punctate and confluent lesion type with comparable WMH volume were compared with respect to the clinical data using Student t test and chi2 test. Direct comparison of visual ratings with volumetry was done using curve fitting. RESULTS: Visual and volumetric assessment detected differences in WMH between groups with respect to gait disturbances and age. WMH volume measurement was more sensitive than visual scores with respect to memory symptoms. Number of lesions nor lesion type correlated with any of the clinical data. For all rating scales, a clear but nonlinear relationship was established with WMH volume. CONCLUSIONS: Visual rating scales display ceiling effects and poor discrimination of absolute lesion volumes. Consequently, they may be less sensitive in differentiating clinical groups

van Straaten, EC; Fazekas, F

2006-01-01

71

Ultrasound Doppler Score Correlates with OMERACT RAMRIS Bone Marrow Oedema and Synovitis Score in the Wrist Joint of Patients with Rheumatoid Arthritis  

DEFF Research Database (Denmark)

PURPOSE: MRI is considered the standard of reference for advanced imaging in rheumatoid arthritis (RA). However, in daily clinical practice ultrasound (US) imaging with Doppler information is more versatile and often used for fast and dynamic assessment of joint inflammation. The aim was to compare low-field MRI scores with the US Doppler measurements in the wrist joint of patients with RA. MATERIAL AND METHODS: Fifty consecutive patients with RA (46 women & 4 men) completed both low-field dedicated extremity MRI (E-scan®, Esaote) and a high-end US (Sequioa®, Siemens) imaging of the wrist before initiating either biological treatment (n = 26) or intraarticular injection of Depomedrole® (n = 24). Mean age was 56 years (range 21 - 83 years); mean disease duration 87.2 months (range 4 - 349 months), mean DAS 28 4,8 (range 2 - 7). MRI was scored according to the OMERACT RAMRIS recommendations and US Doppler colour-fractions were determined. RESULTS: Using Spearman's rho, we found a relatively good to moderate correlation between the US colour-fraction and the total OMERACT bone marrow oedema and synovitis scores on MRI (r = 0.6; p 

Boesen, M; Ellegaard, K

2012-01-01

72

Whole-brain voxel-based correlation analysis between regional cerebral blood flow and intelligence quotient score in Parkinson's disease.  

Science.gov (United States)

The correlation between regional cerebral blood flow (rCBF) and intelligence quotient (IQ) score was investigated in patients with Parkinson's disease (PD) without severe dementia. We analyzed the (9mTc-ethyl cysteinate dimer single-photon emission computed tomography quantitative images and Revised Wechsler Adult Intelligence Scale scores of 44 PD patients using statistical parametric mapping. Verbal IQ positively correlated with rCBF in the right ventral striatum and the bilateral prefrontal cortex, performance IQ positively correlated with rCBF in the right operculum, insula and the left middle temporal gyrus, and full-scale IQ positively correlated with rCBF in the right operculum, insula and the ventral striatum. The identified areas may be functionally related to mild to moderate cognitive impairment in patients with PD. PMID:15492484

Oishi, Kenichi; Ogawa, Masafumi; Oya, Yasushi; Kawai, Mitsuru

2004-01-01

73

Rheumatoid arthritis bone erosion volumes on CT and MRI: reliability and correlations with erosion scores on CT, MRI and radiography.  

DEFF Research Database (Denmark)

OBJECTIVES: To investigate intramodality and intermodality agreements of CT and MRI erosion volumes in metacarpophalangeal (MCP) joints in rheumatoid arthritis (RA), and to compare the volumes with erosion scores for CT, MRI and radiography. METHODS: In total, 17 patients with RA and four healthy controls underwent unilateral CT, MRI and radiography of second to fifth MCP joints in one hand. Erosion volumes (using OSIRIS software) and scores were determined from CT, MRI and radiography (scores only). RESULTS: CT, MRI and radiography detected 77, 62 and 12 erosions, respectively. On CT, the mean erosion volume was 26 mm(3) (median 10; range 0 to 248) and 30 mm(3) (18; 1 to 163) on MRI. Total erosion volumes (per patient/control) were 97 mm(3) (29; 0 to 485) on CT and 90 mm(3) (46; 0 to 389) on MRI. For volumes, Spearman correlation coefficients were 0.96 to 0.99 (CT vs CT), 0.95 to 0.98 (MRI vs MRI) and 0.64 to 0.89 (CT vs MRI), all p<0.01. MRI erosion volumes correlated with the Outcome Measures in Rheumatology Clinical Trials/Rheumatoid Arthritis Magnetic Resonance Imaging Score (OMERACT RAMRIS) erosion scores (0.91 to 0.99; p<0.01) and the Sharp/van der Heijde erosion score (0.49 to 0.63; p<0.01). CONCLUSION: Very high intramodality and high intermodality agreements of CT and MRI erosion volumes were found, encouraging further testing in longitudinal studies. A close correlation with CT and MRI erosion volumes supports the OMERACT RAMRIS erosion score as a valid measure of joint destruction in RA. Udgivelsesdato: 2007-Oct

MØller DØhn, Uffe; Ejbjerg, Bo J

2007-01-01

74

Correcting Two-Sample "z" and "t" Tests for Correlation: An Alternative to One-Sample Tests on Difference Scores  

Science.gov (United States)

In order to circumvent the influence of correlation in paired-samples and repeated measures experimental designs, researchers typically perform a one-sample Student "t" test on difference scores. That procedure entails some loss of power, because it employs N - 1 degrees of freedom instead of the 2N - 2 degrees of freedom of the…

Zimmerman, Donald W.

2012-01-01

75

Correlation of proton MR spectroscopic imaging with Galena's score based on step-section pathologic analysis after radical prostatectomy  

International Nuclear Information System (INIS)

Purpose: To determine whether hydrogen 1 magnetic resonance (MR) spectroscopic imaging can be used to predict aggressiveness of prostate cancer. Materials and Methods: All patients gave informed consent according to an institutionally approved research protocol. A total of 123 patients (median age, 58 years; age range, 40-74 years) who underwent endorectal MR imaging and MR spectroscopic imaging between January 2000 and December 2002 were included. MR imaging and spectroscopy were performed by using combined pelvic phased-array and endorectal probe. Water and lipids were suppressed, and phase-encoded data were acquired with 6.2-mm resolution. Voxels in the peripheral zone were considered suspicious for cancer if (Cho + Cr)/Cit was at least two standard deviations above the normal level, where Cho represents choline-containing compounds, Cr represents creatine and phosphocreatine, and Cit represents citrate. Correlation between metabolite ratio and four Gleason score groups identified at step-section pathologic evaluation (3 + 3, 3 + 4, 4 + 3, and > or =4 + 4) was assessed with generalized estimating equations. Results: Data from 94 patients were included. Pathologic evaluation was used to identify 239 lesions. Overall sensitivity of MR spectroscopic imaging was 56% for tumor detection, increasing from 44% in lesions with Gleason score of 3 + 3 to 89% in lesions with Gleason score greater than or equal to 4 + 4. There was a trend toward increasing (Cho + Cr)/Cit with ind toward increasing (Cho + Cr)/Cit with increasing Gleason score in lesions identified correctly with MR spectroscopic imaging. Tumor volume assessed with MR spectroscopic imaging increased with increasing Gleason score. Conclusion: MR spectroscopic imaging measurement of prostate tumor (Cho + Cr)/Cit and tumor volume correlate with pathologic Gleason score. There is overlap between MR spectroscopic imaging parameters at various Gleason score levels, which may reflect methodologic and physiologic variations. MR spectroscopic imaging has potential in noninvasive assessment of prostate cancer aggressiveness. (author)

76

Improvement of a new rotation function for molecular replacement by designing new scoring functions and dynamic correlation coefficient  

International Nuclear Information System (INIS)

A previously published new rotation function has been improved by using a dynamic correlation coefficient as well as two new scoring functions of relative entropy and mean-square-residues to make the rotation function more robust and independent of a specific set of weights for scoring and ranking. The previously described new rotation function calculates the rotation function of molecular replacement by matching the search model directly with the Patterson vector map. The signal-to-noise ratio for the correct match was increased by averaging all the matching peaks. Several matching scores were employed to evaluate the goodness of matching. These matching scores were then combined into a single total score by optimizing a set of weights using the linear regression method. It was found that there exists an optimal set of weights that can be applied to the global rotation search and the correct solution can be ranked in the top 100 or less. However, this set of optimal weights in general is dependent on the search models and the crystal structures with different space groups and cell parameters. In this work, we try to solve this problem by designing a dynamic correlation coefficient. It is shown that the dynamic correlation coefficient works for a variety of space groups and cell parameters in the global search of rotation function. We also introduce two new matching scores: relative entropy and mean-square-residues. Last but not least, we discussed a valid method for the optimization of the adjustable parameters for matching vectors. (condensed matter: structure, thermal and mechanical properties)

77

[Possible influence of knee scores].  

Science.gov (United States)

This study evaluated 96 knee joints with osteoarthritis (degree I according to Resnick). The patients were examined by three examiners with the following score systems: Larson, Lysholm, Marshall, Orthopädische Arbeitsgemeinschaft Knie (OAK), Hospital for Special Surgery (HSS), Visual Analog Scale (VAS), Tegner activity level, and the International Knee Documentation Committee (IKDC) scoring system. The portion of subjective criteria varied in the different scores between 22 and 95 %. Nevertheless, the agreement between criteria showed high correlations among the different examiners. Depending on the scoring system used and the examiners, different values were achieved. The results were significant at the 5 % level for the numerical results (Friedmantest) and for the total results (Bowkertest). The Lysholm score showed results that were extremely dependent on the different examiners, and the evaluation was very strict. The HSS scoring system was not as strict. The Marshall and the OAK scoring system presented few differences. The Larson score results compared with the OAK, and the Marshall score results showed comparable results in the evaluation by the different examiners. The Visual Analog Scale presented difficulties when used by the patients. The results showed a tendency to the middle values, the patients did not use the whole spread. Apart from this, the correlation between these VAS values and the results of the other scoring systems were high. Since it was only used one time, the Tegner activity level could not efficiently show the limitation caused by knee-joint damage. At the level of 1-4 the Lysholm scoring system and the VSA scale resulted in high values. PMID:10663105

Fuchs, S; Friedrich, M

2000-01-01

78

Correlation between retinopathy of prematurity and clinical risk index for babies score  

OpenAIRE

Background: Several risk factors like prematurity, hyperoxia, hyperglycemia, duration of mechanical ventilation and supplemental oxygen use have been attributed to the occurrence of retinopathy of prematurity (ROP) in low birth weight infants. Clinical Risk Index for Babies (CRIB) score have been used to assess the severity of the newborn's disease and neonatal mortality. The relation between the CRIB score and the incidence of retinopathy of prematurity is less assessed. This study was carri...

Mousa Ahmadpour-kacho; Yadollah Zahed Pasha; Seyed Ahmad Rasoulinejad; Mahmoud Hajiahmadi; Parisa Pourdad

2014-01-01

79

Severity assessment of pulmonary embolism using dual energy CT - correlation of a pulmonary perfusion defect score with clinical and morphological parameters of blood oxygenation and right ventricular failure  

International Nuclear Information System (INIS)

To correlate a Dual Energy (DE)-based visual perfusion defect scoring system with established CT-based and clinical parameters of pulmonary embolism (PE) severity. In 63 PE patients, DE perfusion maps were visually scored for perfusion defects (P-score). Vascular obstruction was quantified using the Mastora score. Both scores were correlated with short-axis diameters of the right and left ventricle, their ratio (RV/LV ratio), width of the pulmonary trunk, a number of clinical parameters and each other. Univariate and multivariate analyses were performed. Times to generate both scores were recorded. After univariate and multivariate analysis, a significant (p 2 (r = -0.50). For the left ventricular diameter, only univariate analysis showed a significant correlation. Mastora score correlated significantly with RV/LV ratio (r = 0.36), width of the pulmonary trunk (r = 0.27), PaO2 (r = -0.41) and troponin I (r = 0.37). Mean time for generating the P-score was significantly shorter than for the Mastora score. A DE-based P-score correlates with a number of parameters of PE severity. It might be easier and faster to perform than some traditional CT scoring methods for vascular obstruction. (orig.)

80

Correlations between age, Charlson score and outcome in clinical unilateral T3a prostate cancer.  

Science.gov (United States)

According to the European Association of Urology (EAU) guidelines, a life expectancy of > 10 years is considered an important factor in the treatment of prostate cancer. The Charlson score is used to predict mortality based on comorbidities. The purpose of this study was to investigate the relationship between age, Charlson score and outcome in patients with cT3a prostate cancer. Between 1987 and 2004, 200 patients, who were with clinical T3a prostate cancer and who underwent radical prostatectomy (RP), were previously detected by digital rectal examination (DRE). Patients were categorized into two age groups (or= 65 years old). Patients were also divided into two groups according to Charlson score ( = 0 and >or= 1). Both age and Charlson score were analyzed regarding their predictive power of patients' outcomes. The mean follow-up period was 70.6 months, and the mean age of patients was 63.3 years. In all, 106 patients were or= 65 years old. Age was a significant predictor of overall survival (OS). A Charlson score of 0 was found in 110 patients, and of >or= 1 in 90 patients. Charlson score was not a significant predictor of biochemical progression-free survival (BPFS), clinical progression-free survival (CPFS) or OS. Cox multivariate analysis showed that margin status was a significant independent factor in BPFS, and cancer volume was a significant independent factor in CPFS. Charlson score does not influence the outcome in patients with clinical locally advanced prostate cancer. Age may influence OS. RP can be performed in motivated healthy older patients. However, the patients need to be counseled regarding possible surgery-related side effects, such as urinary incontinence and erectile dysfunction, which are age- and comorbidity-dependent. PMID:19050679

Hsu, Chao-Yu; Joniau, Steven; Oyen, Raymond; Roskams, Tania; Van Poppel, Hein

2009-01-01

81

Quantification of Emphysema with a Three-Dimensional Chest CT Scan: Correlation with the Visual Emphysema Scoring on Chest CT, Pulmonary Function Tests and Dyspnea Severity  

International Nuclear Information System (INIS)

We wanted to prospectively evaluate the correlation between the quantification of emphysema using 3D CT densitometry with the visual emphysema score, pulmonary function tests (PFT) and the dyspnea score in patients with chronic obstructive pulmonary disease (COPD). Non-enhanced chest CT with 3D reconstruction was performed in 28 men with COPD (age 54-88 years). With histogram analysis, the total lung volume, mean lung density and proportion of low attenuation lung volume below predetermined thresholds were measured. The CT parameters were compared with the visual emphysema score, the PFT and the dyspnea score. A low attenuation lung volume below -950 HU was well correlated with the DLco and FEV1/FVC. A Low attenuation lung volume below -950 HU and -930 HU was correlated with visual the emphysema score. A low attenuation lung volume below -950 HU was correlated with the dyspnea score, although the correlations between the other CT parameters and the dyspnea score were not significant. Objective quantification of emphysema using 3D CT densitometry was correlated with the visual emphysema score. A low attenuation lung volume below -950 HU was correlated with the DLco, the FEV1/FVC and the dyspnea score.

82

Correlation between serum free fatty acids levels and Gensini score in elderly patients with coronary heart disease  

Science.gov (United States)

Objectives To investigate the relationship between serum free fatty acids (FFAs) levels and the severity of coronary artery lesions in elderly patients with coronary heart disease (CAD). Methods A total of 172 elderly patients who underwent coronary angiography were divided into CAD group (n = 128) and non-CAD group (n = 44) according to the results of coronary angiography. Serum FFAs and lipid levels were measured and the Gensini score were calculated. Results No matter the differences between age, gender and the usage of statins or not, there was no statistical significance in FFAs levels (P > 0.05). In terms of the Gensini score, it was higher in patients aged 70–79 years than in patients 60–69 years old [15.00 (5.00, 34.00) vs. 10.00 (2.00, 24.00), P 0.05). Furthermore, the FFAs levels were positively correlated with the Gensini score (r = 0.394, P = 0.005). Regression analysis showed that the FFAs levels were related to the Gensini score independently after adjusting for the other risk factors. Conclusions The serum FFAs levels were associated with the Gensini score in elderly patients with CAD. It might indicate FFAs as a biomarker predicting the severity of coronary artery lesions. PMID:24748883

He, Li-Yun; Zhao, Jun-Feng; Han, Jiang-Li; Shen, Shan-Shan; Chen, Xu-Jiao

2014-01-01

83

Brochopulmonary dysplasia: New high resolution computed tomography scorting system and correlation between the high resolution computed tomography score and clinical severity  

Energy Technology Data Exchange (ETDEWEB)

To develop an high resolution computed tomography (HRCT) scoring system for the assessment of bronchopulmonary dysplasia (BPD) and determine its usefulness as compared with the chest radiographic score. Forty-two very low-birth-weight preterm infants with BPD (25 male, 17 female) were prospectively evaluated with HRCT performed at the mean age of 39.1-week postmenstrual age. Clinical severity of BPD was categorized as mild, moderate or severe. The HRCT score (0-36) of each patient was the sum of the number of bronchopulmonary segments with 1) hyperaeration and 2) parenchymal lesions (linear lesions, segmental atelectasis, consolidation and architectural distortion), respectively. We compared the HRCT scores with the chest radiographic scores (the Toce system) in terms of correlation with clinical severity. The HRCT score had good interobserver (r = 0.969, p < 0.001) and intraobserver (r = 0.986, p < 0.001) reproducibility. The HRCT score showed better correlation (r = 0.646, p < 0.001) with the clinical severity of BPD than the chest radiographic score (r = 0.410, p = 0.007). The hyperaeration score showed better correlation (r = 0.738, p < 0.001) with the clinical severity of BPD than the parenchymal score (r = 0.523, p < 0.001). We have developed a new HRCT scoring system for BPD based on the quantitative evaluation of pulmonary abnormalities of BPD consisting of the hyperaeration score and the parenchymal score. The HRCT score shows better correlation with the clinical severity of BPD than the radiographic score.

Shin, Sumi; Kim, Woo Sun; Cheon, Jung Eun; Kim, Han Suk; Lee, Whal; Jung, Ah Young; Kim, In One; Choi, Jung Hwan [Seoul National University College of Medicine, Seoul (KR)

2013-04-15

84

Brochopulmonary dysplasia: New high resolution computed tomography scorting system and correlation between the high resolution computed tomography score and clinical severity  

International Nuclear Information System (INIS)

To develop an high resolution computed tomography (HRCT) scoring system for the assessment of bronchopulmonary dysplasia (BPD) and determine its usefulness as compared with the chest radiographic score. Forty-two very low-birth-weight preterm infants with BPD (25 male, 17 female) were prospectively evaluated with HRCT performed at the mean age of 39.1-week postmenstrual age. Clinical severity of BPD was categorized as mild, moderate or severe. The HRCT score (0-36) of each patient was the sum of the number of bronchopulmonary segments with 1) hyperaeration and 2) parenchymal lesions (linear lesions, segmental atelectasis, consolidation and architectural distortion), respectively. We compared the HRCT scores with the chest radiographic scores (the Toce system) in terms of correlation with clinical severity. The HRCT score had good interobserver (r = 0.969, p < 0.001) and intraobserver (r = 0.986, p < 0.001) reproducibility. The HRCT score showed better correlation (r = 0.646, p < 0.001) with the clinical severity of BPD than the chest radiographic score (r = 0.410, p = 0.007). The hyperaeration score showed better correlation (r = 0.738, p < 0.001) with the clinical severity of BPD than the parenchymal score (r = 0.523, p < 0.001). We have developed a new HRCT scoring system for BPD based on the quantitative evaluation of pulmonary abnormalities of BPD consisting of the hyperaeration score and the parenchymal score. The HRCT score shows better correlation with the clinical severity of BPD than the radiographic score.

85

The Correlation of Brody High Resolution Computed Tomography Scoring System with Clinical Status and Pulmonary Function Test in Patients with Cystic Fibrosis  

Directory of Open Access Journals (Sweden)

Full Text Available Background: To reduce the mortality and morbidity rates of cystic fibrosis (CF patients, and to have an effective clinical management, it is important to monitor the progression of the disease. The aim of this study was to evaluate the progression of lung disease in CF patients by means of assessing the correlation of the CT scoring system with clinical status and pulmonary function test at the Pediatric Pulmonary Ward of Masih Daneshvari Hospital in 2008. Methods: Pulmonary high resolution computed tomography (HRCT was performed in 23 CF patients using the Brody's scoring system. Morphologic signs as well as the extent and severity of each sign were scored, and the total score was calculated. The correlation of HRCT scores (total score as well as the score for each parameter with Shwachman Kuczycki scoring system and pulmonary function test were examined. Results: The study included 9 female and 14 male patients with an age range of 5-23 years (mean: 13.42 years. Bronchiectasis (100% and peribronchial wall thickening (100% were the most frequent CT abnormalities. Mucus plugging, air trapping and parenchymal involvements were respectively seen in 95.7%, 91.3% and 47.8% of patients. The overall CT score for all patients was 57.6±24.2 (means±SD. The results of pulmonary function test showed a restrictive pattern; however, in 5.3% of the patients PFT was normal. The overall Shwachman-Kulczycki score was 53.48±13.8. There was a significantly (P=0.015 negative correlation between the total CT score and Shwachman-Kulczycki score; however, there was no significant correlation between total CT score and the results of PFT (P=0.481. Conclusion: The Brody's scoring system for high resolution computed tomography seems to be a sensitive and efficient method to evaluate the progression of CF, and can be more reliable when we combine the CT scores with clinical parameters

Soheila Khalilzadeh

2011-03-01

86

Severity assessment of pulmonary embolism using dual energy CT - correlation of a pulmonary perfusion defect score with clinical and morphological parameters of blood oxygenation and right ventricular failure  

Energy Technology Data Exchange (ETDEWEB)

To correlate a Dual Energy (DE)-based visual perfusion defect scoring system with established CT-based and clinical parameters of pulmonary embolism (PE) severity. In 63 PE patients, DE perfusion maps were visually scored for perfusion defects (P-score). Vascular obstruction was quantified using the Mastora score. Both scores were correlated with short-axis diameters of the right and left ventricle, their ratio (RV/LV ratio), width of the pulmonary trunk, a number of clinical parameters and each other. Univariate and multivariate analyses were performed. Times to generate both scores were recorded. After univariate and multivariate analysis, a significant (p < 0.05) correlation with the P-score was shown for the Mastora score (r = 0.65), RV/LV ratio (r = 0.47), width of the pulmonary trunk (r = 0.26), troponin I (r = 0.43) and PaO{sub 2} (r = -0.50). For the left ventricular diameter, only univariate analysis showed a significant correlation. Mastora score correlated significantly with RV/LV ratio (r = 0.36), width of the pulmonary trunk (r = 0.27), PaO{sub 2} (r = -0.41) and troponin I (r = 0.37). Mean time for generating the P-score was significantly shorter than for the Mastora score. A DE-based P-score correlates with a number of parameters of PE severity. It might be easier and faster to perform than some traditional CT scoring methods for vascular obstruction. (orig.)

Thieme, Sven F. [Ludwig-Maximilians-Universitaet, Department of Clinical Radiology, Muenchen (Germany); Institut fuer Klinische Radiologie der LMU Muenchen, Muenchen (Germany); Ashoori, Nima; Bamberg, Fabian; Sommer, Wieland H.; Johnson, Thorsten R.C.; Maxien, Daniel; Helck, Andreas D.; Reiser, Maximilian F.; Nikolaou, Konstantin [Ludwig-Maximilians-Universitaet, Department of Clinical Radiology, Muenchen (Germany); Leuchte, Hanno; Becker, Alexander [Ludwig-Maximilians-Universitaet, Department of Medicine I, Muenchen (Germany); Behr, Juergen [Ludwig-Maximilians-Universitaet, Department of Medicine I, Muenchen (Germany); Berufsgenossenschaftliches Universitaetsklinikum Bergmannsheil GmbH Ruhr-Universitaet Bochum, Department of Medicine III, Bochum (Germany)

2012-02-15

87

Radiological evaluation of chronic hemophilic arthropathy by the Pettersson score: Problems in correlation in adult patients  

Energy Technology Data Exchange (ETDEWEB)

This study deals with the distribution and extent of hemophilic arthropathy (HA) in 52 adult patients suffering from severe hemophilia A. A clinical and radiological evaluation was undertaken and the results were compared. The limitations of the currently used radiological scoring system are discussed. (orig.)

Hamel, J.; Pohlmann, H.; Schramm, W.

1988-01-01

88

Radiological evaluation of chronic hemophilic arthropathy by the Pettersson score: Problems in correlation in adult patients  

International Nuclear Information System (INIS)

This study deals with the distribution and extent of hemophilic arthropathy (HA) in 52 adult patients suffering from severe hemophilia A. A clinical and radiological evaluation was undertaken and the results were compared. The limitations of the currently used radiological scoring system are discussed. (orig.)

89

Protein digestibility-corrected amino acid scores (PDCAAS) for soy protein isolates and concentrate: criteria for evaluation.  

Science.gov (United States)

Protein quality, as determined by the PDCAAS method, is a measure of a protein's ability to provide adequate levels of essential amino acids for human needs. PDCAAS is calculated using an amino acid profile and true digestibility of a food protein. Soy protein is recognized as a high quality plant protein, but published PDCAAS values may vary based on the soy protein ingredient as well as the reproducibility and accuracy of the testing methods. Comparison of PDCAAS values for four differently processed soy ingredients, including three isolated soy proteins (ISP) and one soy protein concentrate (SPC), was made using two different laboratories with evaluation of the impact of the reproducibility and accuracy of amino acid profiles. PDCAAS calculations, using amino acid values from one laboratory, yielded a truncated PDCAAS of 1.00 for all four ingredients, while a second laboratory provided statistically significantly lower scores (0.95-1.00). We conclude that analytical method error can be a significant contributor to PDCAAS differences and can be mitigated by the application of amino acid nitrogen recovery correction factors. PMID:22017752

Hughes, Glenna J; Ryan, David J; Mukherjea, Ratna; Schasteen, Charles S

2011-12-14

90

Evaluation of selection criteria in Cicer arietinum L. using correlation coefficients and path analysis  

Directory of Open Access Journals (Sweden)

Full Text Available The study pertaining to the evaluation of selection criteria in chickpea using correlation coefficients and path analysis was carried out in the Department of Plant Breeding and Genetics, University of Agriculture, Faisalabad for a period of two years. Experimental material comprised of twenty chickpea genotypes. The genotypes demonstrated highly significant differences (P<0.01 for all the traits studied. The results of correlation analysis revealed that that grain yield plant-1 had significant genotypic and highly significant phenotypic relationship with primary branches, pods plant-1, seeds plant-1, seeds pod-1 and total biological yield. The path coefficient analysis based on grain yield plant-1, as a dependent variable, exposed that all of the other traits, except days to flowering, days to maturity and secondary branches exhibited positive direct effects. The path analysis confirmed that biological yield followed by number of seeds pod-1, 100-grain weight, had the maximum positive direct influence on grain yield plant-1. Therefore, this study suggests that chickpea improvement progarmme could be based on these characters as selection criteria.

Muhammad Amjad Ali

2009-03-01

91

Correlation between parathormone and coronary artery calcium scoring and coronary artery disease  

OpenAIRE

Background: It has been shown that coronary artery calcium scoring (CACS) can be used as a diagnostic method in coronary artery disease (CAD). The relationship between CACS and calcium metabolism in the body has been shown. The arterial calcification is an organized process similar to bone formation which is controled by parathormone (PTH). The relationship between PTH as an osteoregulatory factor and CACS has been also indicated. In this study, we tried to assess the value of serum PTH and C...

Af, Zand Parsa; Gilani Larimi N; Esteghamati A; Motevalli M

2013-01-01

92

Correlation between PSA, bone scan and Gleason score in patients with prostate cancer  

International Nuclear Information System (INIS)

Full text: Prostate cancer is the third most common cancer among Peruvian males. Although radionuclide bone scans (BS) are frequently recommended as part of the staging evaluation for newly diagnosed prostate cancer, most scans are negative for metastases. It has been suggested that a routine bone scan is unnecessary in recently diagnosed prostate cancer if serum PSA is under 10 ng/mL. We hypothesized that Gleason score plus prostate-specific antigen (PSA), could predict for a positive bone scan (better that PSA alone), and that a low - risk group of patients could be identified in whom BS might be omitted. All patients who had both pathologic review of their prostate cancer biopsies and radionuclide BS at our institution from 1/93 to 12/95 were studied. Gleason score, PSA, and bone scan (Soloway Index) were determined in 165 patients. Bivariate analysis using chi (x2) was performed. The mean age of the 165 patients was 71.3 years, 109/165 (66.1%) had a 7-9 Gleason score and only 9/165 (5.5%) were well differentiated prostrate cancer. 82/165 (49.7%) had negative BS. When classifying patients according to their histological grade, the PSA median values were 11.8 ng/mL, 74.8 ng/mL and 116.4 ng/mL in well, median and poorly differentiated prostate cancer respectively. Using a cut off point of 10 ng/mL of PSA, the probability of having a positive BS in Gleason 7, 8 and 9 tumors were 0.109, 0.121 and 0.133 respectively. By using a cut off point of 20 ng/mL of PSA the possicut off point of 20 ng/mL of PSA the possibility to have a positive BS in Gleason 7, 8 and 9 tumours were 0.182, 0.206 and 0.224 respectively. Gleason score plus PSA were independent predictors for a positive radionuclide BS in newly diagnosed prostate cancer patients. Considering that most of our patients have Gleason 7-9, the risk of bone metastases despite PSA levels between 10 - 20 ng/mL is not negligible. In our opinion, it is important to continue including bone scan in the staging assessment of prostate cancer. (author)

93

The effect of recent trauma on serum complement activation and serum C3 levels correlated with the injury severity score  

OpenAIRE

PURPOSE: The objective of this prospective pilot study was to estimate serum C3 levels and complement activation within 12 hours of injury and to correlate them with abbreviated injury score (AIS) so as to predict the outcome of injury in terms of mortality or sepsis. METHODS: The test group (n=30) of patients with < 12 hours of injury were assessed by the AIS-80 and compared with a control group (n=10). Serum C3 levels were estimated by the single radial immunodiffusion technique and comp...

Sharma D; Sarda A; Bhalla S; Goyal A.; Kulshreshta V

2004-01-01

94

Coefficients of Correlation of IQ's on the WAIS-R with Standard Age Scores on the Stanford-Binet, 4th Edition for Previously Identified Mentally Handicapped Adolescents.  

Science.gov (United States)

This paper presents a study regarding the correlation of the Stanford-Binet: 4th Edition Intelligence Quotient (IQ) scores with the Wechsler Adult Intelligence Scale-Revised (WAIS-R) IQ scores for the purpose of improving the identification process for educable mentally handicapped (EMH) school age adolescents and young adults. The sample included…

Richardson, John C.

95

Correlation between Grade Point Averages and Student Evaluation of Teaching Scores: Taking a Closer Look  

Science.gov (United States)

One of the most contentious potential sources of bias is whether instructors who give higher grades receive higher ratings from students. We examined the grade point averages (GPAs) and student ratings across 2073 general education religion courses at a large private university. A moderate correlation was found between GPAs and student evaluations…

Griffin, Tyler J.; Hilton, John, III.; Plummer, Kenneth; Barret, Devynne

2014-01-01

96

Time course of lesion development in patients with acute brain stem infarction and correlation with NIHSS score  

Energy Technology Data Exchange (ETDEWEB)

Background and purpose: diffusion weighted magnetic resonance imaging (MRI) is highly sensitive in detecting acute supratentorial cerebral ischemia and Diffusion Weighted Imaging (DWI) lesion size has been shown to correlate strongly with the neurologic deficit in middle cerebral artery territory stroke. However, data concerning infratentorial strokes are rare. We examined the size and evolution of acute brain stem ischemic lesions and their relationship to neurological outcome. Methods: brain stem infarctions of 11 patients were analyzed. We performed DWI in all patients and in 7/11 patients within 24 h, T2W sequences within the first 2 weeks (10/11 patients) and follow-up MRI (MR2) within 3-9 months (median 4.8 months) later (12/12 patients). Lesion volumes were compared with early and follow-up neurologic deficit as determined by National Institutes of Health Stroke Scale (NIHSS) score. Results: the relative infarct volumes--with MR2 lesion size set to 100%--decreased over the time (P<0.02) with a mean shrinking factor of 3.3 between DWI (MR0) and the follow-up MRT (P<0.02), and 1.6 between early T2W (MR1) and MR2 (P<0.04). The mean DWI volume size (MR0) was larger than the early T2W (P<0.02). Although neurological outcome was good in all patients (mean NIHSS score of 1.3 at follow-up), early NIHSS and follow-up NIHSS scores were strongly correlated (r=0.9, P<0.00). NIHSS score at follow-up was highly correlated with lesion size of DWI (MR0; r=0.71, P<0.04) and T2W of MR1 (r=0.86, P<0.001). Conclusions: in this study, we saw a shrinking of the brain stem infarct volume according to clinical improvement of patients. Great extension of restricted diffusion in the acute stage does not necessarily implicate a large resulting infarction or a bad clinical outcome.

Fitzek, Sabine E-mail: sabine.fitzek@med.uni-jena.de; Fitzek, Clemens; Urban, Peter Paul; Marx, Juergen; Hopf, Hanns Christian; Stoeter, Peter

2001-09-01

97

Time course of lesion development in patients with acute brain stem infarction and correlation with NIHSS score  

International Nuclear Information System (INIS)

Background and purpose: diffusion weighted magnetic resonance imaging (MRI) is highly sensitive in detecting acute supratentorial cerebral ischemia and Diffusion Weighted Imaging (DWI) lesion size has been shown to correlate strongly with the neurologic deficit in middle cerebral artery territory stroke. However, data concerning infratentorial strokes are rare. We examined the size and evolution of acute brain stem ischemic lesions and their relationship to neurological outcome. Methods: brain stem infarctions of 11 patients were analyzed. We performed DWI in all patients and in 7/11 patients within 24 h, T2W sequences within the first 2 weeks (10/11 patients) and follow-up MRI (MR2) within 3-9 months (median 4.8 months) later (12/12 patients). Lesion volumes were compared with early and follow-up neurologic deficit as determined by National Institutes of Health Stroke Scale (NIHSS) score. Results: the relative infarct volumes--with MR2 lesion size set to 100%--decreased over the time (P<0.02) with a mean shrinking factor of 3.3 between DWI (MR0) and the follow-up MRT (P<0.02), and 1.6 between early T2W (MR1) and MR2 (P<0.04). The mean DWI volume size (MR0) was larger than the early T2W (P<0.02). Although neurological outcome was good in all patients (mean NIHSS score of 1.3 at follow-up), early NIHSS and follow-up NIHSS scores were strongly correlated (r=0.9, P<0.00). NIHSS score at follow-up was highly correlated with lesion size of DWI (MR0; r=0.71, P<0.04) and T2W size of DWI (MR0; r=0.71, P<0.04) and T2W of MR1 (r=0.86, P<0.001). Conclusions: in this study, we saw a shrinking of the brain stem infarct volume according to clinical improvement of patients. Great extension of restricted diffusion in the acute stage does not necessarily implicate a large resulting infarction or a bad clinical outcome

98

State level correlations between high heart attack and stroke symptomology knowledge scores and CVD risk factors and mortality rates  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction: In 2008, cardiovascular disease (CVD accounted for one in three deaths in the United States. Epidemiological analyses suggest that two or more risk factors are the indicator of high risk and/or poor CVD outcomes. Knowledge of heart attack and stroke symptomology has been the focus of much research based on the assumption that accurate identification of an event is critical to reducing time to treatment. There is a paucity of research showing a clear association between knowledge of heart attack and stroke symptomology, risk factors, and mortality rates. In this study, we hypothesized that high stroke and heart attack symptomology knowledge scores would correspond to lower stroke or CVD mortality rankings as well as to a lower prevalence of two or more CVD risk factors. Methods: State was the unit of analysis used to examine data from two different sources and combined into a customized database. The first source was a multiyear Behavioral Risk Factor Surveillance Survey (BRFSS heart attack and stroke symptom knowledge module database. CVD and stroke mortality data used came from the American Heart Association’s (AHA 2012 Heart Disease and Stroke Statistics Update. Spearman’s Rho was the test statistic. Results: A moderate negative correlation was found between high heart attack and stroke symptom knowledge scores and the percentage of adults with two or more CVD or stroke risk factors. Likewise, a similar correlation resulted from the two variables, high heart attack and stroke symptoms knowledge score and CVD mortality rank. Conclusions: This study demonstrated a significant relationship between high heart attack and stroke symptom knowledge and lower CVD mortality rates and lower prevalence of two or more CVD risk factors at the state level. Our findings suggest that it is important to continue education efforts regarding heart attack and stroke symptom knowledge. Pharmacists are one group of health care providers who could enhance the needed public health education efforts.

Mary Nawal Lutfiyya

2013-09-01

99

Distribution of brain infarction in children with tuberculous meningitis and correlation with outcome score at 6 months  

International Nuclear Information System (INIS)

Prognostic indicators for tuberculous meningitis (TBM) offer realistic expectations for parents of affected children. Infarctions affecting the basal ganglia are associated with a poor outcome. To correlate the distribution of infarction in children with TBM on CT with an outcome score (OS). CT brain scans in children with TBM were retrospectively reviewed and the distribution of infarctions recorded. The degree of correlation with OS at 6 months was determined. There was a statistically significant association between all sites of infarction (P = 0.0001-0.001), other than hemispheric (P = 0.35), and outcome score. There was also a statistically significant association between all types of infarction (P = 0.0001-0.02), other than hemispheric (P = 0.05), and overall poor outcome. The odds ratio for poor outcome with bilateral basal ganglia and internal capsule infarction was 12. The odds ratio for poor outcome with 'any infarction' was 4.91 (CI 2.24-10.74), with 'bilateral infarctions' 8.50 (CI 2.49-28.59), with basal ganglia infarction 5.73 (CI 2.60-12.64), and for hemispheric infarction 2.30 (CI 1.00-5.28). Infarction is associated with a poor outcome unless purely hemispheric. MRI diffusion-weighted imaging was not part of this study, but is likely to play a central role in detecting infarctions not demonstrated by CT. (orig.)

100

Correlation between a new visual prostate symptom score (VPSS) and uroflowmetry parameters in men with lower urinary tract symptoms  

Scientific Electronic Library Online (English)

Full Text Available SciELO South Africa | Language: English Abstract in english OBJECTIVE: A visual prostate symptom score (VPSS) compared with the international prostate symptom score (IPSS) for evaluation of lower urinary tract symptoms (LUTS) can be completed without physician assistance by a significantly larger proportion of men with limited education. We aimed to evaluate [...] the correlation of the VPSS and IPSS with uroflowmetry parameters. METHODS: Men with LUTS were requested to complete the IPSS and VPSS, consisting of pictograms to evaluate urinary frequency, nocturia, force of the stream and quality of life. The maximum (Qmax) and average urinary flow rate (Qave), voided volume (VV) and post-void residual (PVR) urine volumes were measured. Statistical analysis was performed using the Mann-Whitney and Spearman's tests. RESULTS: The study included 93 men (mean age 64 years, range 33 -85), with VV >150 ml in 66 (71%) and 150 ml there were significant negative correlations between the IPSS and Qmax (r=-0.30, p=0.016), the IPSS and Qave (r=-0.29, p=0.018), the VPSS and Qmax (r=-0.38, p

C F, Heyns; C L E, van der Walt; A E, Groeneveld.

2012-04-01

101

Correlation Between Cytokine Levels in Nasal Fluid and Scored Clinical Parameters in Patients with Nasal Polyposis  

OpenAIRE

The aim of this study was to compare the cytokine levels in nasal fluid in subjects with nasal polyposis (NP) and co-morbid asthma and NP patients without asthma and to correlate these levels with clinical parameters of severity of disease. Forty NP patients (20 asthmatic and 20 nonasthmatic) were enrolled. Nasal secretion samples were collected from nasal cavities of all 40 subjects. The levels of Th1 cytokines IL-2, IL-12 and IFN-?, Th2 cytokines IL-4, IL-5, IL-6, and IL-10, chemokine IL-8...

Peric?, Aleksandar; Vojvodic?, Danilo; Peric?, Aneta V.; Radulovic?, Vesna; Miljanovic?, Olivera

2012-01-01

102

The effect of recent trauma on serum complement activation and serum C3 levels correlated with the injury severity score  

Directory of Open Access Journals (Sweden)

Full Text Available PURPOSE: The objective of this prospective pilot study was to estimate serum C3 levels and complement activation within 12 hours of injury and to correlate them with abbreviated injury score (AIS so as to predict the outcome of injury in terms of mortality or sepsis. METHODS: The test group (n=30 of patients with < 12 hours of injury were assessed by the AIS-80 and compared with a control group (n=10. Serum C3 levels were estimated by the single radial immunodiffusion technique and complement activation by both two-dimensional and counter immuno-electrophoresis. Statistical analysis was performed using the correlation regression analysis and the minimum discrimination information statistics (MDIS analysis. RESULTS: Serum C3 levels were not reduced in patients with injury severity score (ISS < 12 (n=7. There was a statistically significant difference of serum C3 levels in patients with ISS between 12 and 29 (n=15 and in patients with ISS more than 29 (n=9. Complement activation also correlated well with ISS (p <0.05. Complement activation and serum C3 levels were found to influence subsequent development of septic complications in the post injury period, being significantly lower in patients who developed septic complications. Complement alterations in trauma patients were a direct result of the trauma since they were not seen in patients undergoing surgery. CONCLUSIONS: ISS is a good prognosticator of outcome of trauma and serum C3 levels and complement activation are good predictors for mortality and development of septic complications in recently injured patients. These may prove to be effective parameters in the management of the patients with injury.

Sharma D

2004-01-01

103

Severity of acute pulmonary embolism: evaluation of a new spiral CT angiographic score in correlation with echocardiographic data  

International Nuclear Information System (INIS)

The purpose of this study was to investigate whether the severity of acute pulmonary embolism (PE) could be quantitatively assessed with spiral CT angiography (SCTA). Thirty-six consecutive patients without underlying cardiopulmonary disease and high clinical suspicion of PE underwent prospectively thin-collimation SCTA and echocardiography at the time of the initial diagnosis (T0) and after initial therapy (T1; mean interval of time T1-T2: 32 days). The CT severity score was based on the percentage of obstructed surface of each central and peripheral pulmonary arterial section using a 5-point scale (1: 40 mm Hg). The SCTA depicted acute PE in all patients at T0 with complete resolution of endovascular clots in 10 patients at T1. At T0, the mean percentage of obstruction of the pulmonary arterial bed was significantly higher in the 22 patients with echocardiographic signs of severity (56±13 vs 28±32%; p<0.001). A significant reduction in the mean percentage of pulmonary artery obstruction was observed in the 19 patients wuction was observed in the 19 patients with resolution of echocardiographic criteria of severity between T0 and T1 T0: 57±14%; T1: 7±11%; p<0.001. The threshold value for severe PE on CT angiograms was 49% (sensitivity: 0.773; specificity: 0.214). The mean (±SD) pulmonary artery pressure was significantly higher in the 26 patients with more than 50% obstruction of the pulmonary artery bed (45±15 mm Hg) than in the 10 patients with less than 50% obstruction of pulmonary artery bed at T0 (31±11 mm Hg; p<0.01). The CT severity score evaluated in the present study enables quantitative assessment of acute PE severity on spiral CT angiograms, readily applicable in routine clinical practice. (orig.)

104

[Comparison of knee ligament scores and rating systems].  

Science.gov (United States)

The results of the treatment of knee instabilities are evaluated by different scoring systems including subjective and/or objective criteria. Because of their number and their different criteria a comparison between the scoring systems is still a problem. The aim of this study was to analyze 14 different scoring-systems and prove the comparison of the commonly used rating scales. 116 patients with anterior or anterior-medial knee instabilities were followed up at least 2 years postoperatively. The evaluation was performed according to the criteria of the used rating-scales. The Lysholm I scoring system showed the highest mean total score (92 points). The scales that gave the highest correlation were the Cincinnati and ARPEGE scoring system (r = 0.97). The Lysholm I Scale and the Barrack Scale correlated least well (r = 0.711). This study documents that a transfer of results from one scoring system to another is not possible. A comparison between these scoring systems is only possible after adjusting the total points, the quality and the quantity of each criterion and component of the scoring system. This can done by using a standardized rating scale like the IKDC-score. PMID:9199076

Peters, G; Wirth, C J; Kohn, D

1997-01-01

105

Correlation of volumetric mismatch and mismatch of Alberta Stroke program Early CT scores on CT perfusion maps  

International Nuclear Information System (INIS)

We aimed to determine if volumetric mismatch between tissue at risk and tissue destined to infarct on computed tomography perfusion (CTP) can be described by the mismatch of Alberta Stroke Program Early CT Score (ASPECTS). Forty patients with nonlacunar middle cerebral artery infarct 6 s and <2.0 mL per 100 g, respectively. Two other raters assigned ASPECTS to the same MTT and CBV maps while blinded to the volumetric data. Volumetric mismatch was deemed present if ?20%. ASPECTS mismatch (=CBV ASPECTS - MTT ASPECTS) was deemed present if ?1. Correlation between the two types of mismatches was assessed by Spearman's coefficient (?). ROC curve analyses were performed to determine the optimal ASPECTS mismatch cut point for volumetric mismatch ?20%, ?50%, ?100%, and ?150%. Median volumetric mismatch was 130% (range 10.9-2,031%) with 31 (77.5%) being ?20%. Median ASPECTS mismatch was 2 (range 0-6) with 26 (65%) being ?1. ASPECTS mismatch correlated strongly with volumetric mismatch with ? = 0.763 [95% CI 0.585-0.870], p < 0.0001. Sensitivity and specificity for volumetric mismatch ?20% was 83.9% [95% CI 65.5-93.5] and 100% [95% CI 65.9-100], respectively, using ASPECTS mismatch ?1. Volumetric mismatch ?50%, ?100%, and ?150% were optimally identified using ASPECed using ASPECTS mismatch ?1, ?2, and ?2, respectively. On CTP, ASPECTS mismatch showed strong correlation to volumetric mismatch. ASPECTS mismatch ?1 was the optimal cut point for volumetric mismatch ?20%. (orig.)

106

The relationship between observer-based toxicity scoring and patient assessed symptom severity after treatment for head and neck cancer. A correlative cross sectional study of the DAHANCA toxicity scoring system and the EORTC quality of life questionnaires  

DEFF Research Database (Denmark)

BACKGROUND AND PURPOSE: Morbidity is an important issue in cancer research. The observer-based toxicity scoring system used by DAHANCA (the Danish head and neck cancer study group) has proved itself sensitive to differences in toxicity in a large randomised study, but like other toxicity scoring systems it has not been formally validated. Conversely, the EORTC quality of life questionnaire (QLQ) has been validated as a tool for collecting information about the consequences of disease and treatment on the well being of cancer patients. The purpose of this study was to examine the relationship between the two methods of side effect recording. PATIENTS AND METHODS: One hundred and sixteen recurrence free patients with laryngeal (n=44), pharyngeal (n=34) and oral cavity (n=38) cancer attending follow-up after radiotherapy (n=83) or surgery (n=33) completed EORTC C30, the core questionnaire concerning general symptoms and function and EORTC H&N35 the head and neck specific questionnaire. The attending physicians in the follow-up clinic evaluated and recorded DAHANCA toxicity scores on the same patients. RESULTS: The DAHANCA toxicity scoring system and the EORTC QLQ correlated with several clinical endpoints. The conceptually similar endpoints of the two methods correlated significantly. The objective endpoints of the DAHANCA scoring system were only correlated with quality of life endpoints to a very low degree. The DAHANCA toxicity scores had a low sensitivity (0.48-0.74) in detecting equivalent subjective complaints from the questionnaires and the observer-based scoring system severely underestimated patient complaints. A specific patient group where the DAHANCA score had a higher tendency to fail could not be detected. CONCLUSION: The DAHANCA toxicity score is an effective instrument in assessing objective treatment induced toxicity in head and neck cancer patients but insensitive and non-specific with regard to patient assessed subjective endpoints. This weakness seems inherent in an observer-based scoring system, and will probably also apply to newer ones like CTCAE 3.0.

Jensen, Kenneth; Bonde Jensen, Anders

2006-01-01

107

The relationship between observer-based toxicity scoring and patient assessed symptom severity after treatment for head and neck cancer. A correlative cross sectional study of the DAHANCA toxicity scoring system      and the EORTC quality of life questionnaires  

DEFF Research Database (Denmark)

BACKGROUND AND PURPOSE: Morbidity is an important issue in cancer       research. The observer-based toxicity scoring system used by DAHANCA (the       Danish head and neck cancer study group) has proved itself sensitive to       differences in toxicity in a large randomised study, but like other       toxicity scoring systems it has not been formally validated. Conversely,       the EORTC quality of life questionnaire (QLQ) has been validated as a tool       for collecting information about the consequences of disease and treatment       on the well being of cancer patients. The purpose of this study was to       examine the relationship between the two methods of side effect recording.       PATIENTS AND METHODS: One hundred and sixteen recurrence free patients       with laryngeal (n=44), pharyngeal (n=34) and oral cavity (n=38) cancer       attending follow-up after radiotherapy (n=83) or surgery (n=33) completed       EORTC C30, the core questionnaire concerning general symptoms and function       and EORTC H&N35 the head and neck specific questionnaire. The attending       physicians in the follow-up clinic evaluated and recorded DAHANCA toxicity       scores on the same patients. RESULTS: The DAHANCA toxicity scoring system       and the EORTC QLQ correlated with several clinical endpoints. The       conceptually similar endpoints of the two methods correlated       significantly. The objective endpoints of the DAHANCA scoring system were       only correlated with quality of life endpoints to a very low degree. The       DAHANCA toxicity scores had a low sensitivity (0.48-0.74) in detecting       equivalent subjective complaints from the questionnaires and the       observer-based scoring system severely underestimated patient complaints.       A specific patient group where the DAHANCA score had a higher tendency to       fail could not be detected. CONCLUSION: The DAHANCA toxicity score is an       effective instrument in assessing objective treatment induced toxicity in       head and neck cancer patients but insensitive and non-specific with regard       to patient assessed subjective endpoints. This weakness seems inherent in       an observer-based scoring system, and will probably also apply to newer       ones like CTCAE 3.0

Jensen, Kenneth; Jensen, Anders Bonde

2006-01-01

108

Pulmonary Wegener' s granulomatosis. Correlation between high-resolution CT findings and clinical scoring of disease activity  

International Nuclear Information System (INIS)

It has been considered that the treatment to the patient with Wegener granulomatosis (WG) it should be adapted to the activity of the illness. In this work it was looked for to evaluate if the discoveries in the high-resolution tomography of thorax of in several clinical stadiums of the illness were correlated with the clinical score of activity of the illness. 73 patients were studied with WG (30 women, 43 men) with age between 34 and 71 years. They were carried out 98 radiological exams. The pursuit was made with bronchoscopy, BAL, tests of pulmonary function, Rx thorax. The high-resolution tomography was taken before the bronchoscopy and it was the base for the realization of the BAL. Patient with Rx normal thorax they were also included

109

Joint health scores in a haemophilia A cohort from Pakistan with minimal or no access to factor VIII concentrate: correlation with thrombin generation and underlying mutation.  

Science.gov (United States)

Haemophilia A is associated with recurrent joint bleeding which leads to synovitis and debilitating arthropathy. Coagulation factor VIII level is an important determinant of bleed number and development of arthropathy . The aim of this study was to compare the haemophilia joint health score (HJHS) and Gilbert score with severity, age, thrombin generation (TG) and underlying mutation in a haemophilia A cohort which had minimal access to haemostatic replacement therapy. Ninety-two haemophilia A individuals were recruited from Pakistan. Age, age at first bleed, target joints, haemophilic arthropathy joints, HJHS and Gilbert score were recorded. A strong correlation was found between HJHS and Gilbert score (r = 0.98), both were significantly higher in severe (n = 59) compared with non-severe (n = 29) individuals before the age of 12 years (P ? 0.01) but not thereafter. When individuals were divided according to developmental age (16 years), both HJHS and Gilbert score were significantly lower in the youngest group (P ? 0.001), there was no difference between 12-16 years and >16 years. In severe individuals there was no correlation between in vitro TG and joint score, whereas in non-severe individuals there was a weak negative correlation. In the severe group, no significant difference was observed for either joint score according to the underlying mutation type (inversion, missense, nonsense, frameshift). In this cohort of haemophilia A individuals with minimal access to haemostatic treatment, haemophilic arthropathy correlated with severity and age; among severe individuals, joint health scores did not relate to either the underlying mutation or in vitro TG. PMID:24354535

Khanum, F; Bowen, D J; Kerr, B C; Collins, P W

2014-05-01

110

Correlations between scores on the Wechsler Intelligence Scale for Children-III and the General Purpose Abbreviated Battery of the Stanford-Binet IV.  

Science.gov (United States)

Estimations of some relationships among scores on the "General Purpose Abbreviated Battery" of the Stanford-Binet: Fourth Edition and the Wechsler Intelligence Scale for Children-III were based on the responses of 14 boys and 18 girls enrolled in Grades 3, 4, and 5 and who took both tests. Of 13 Pearson correlations between the Binet IV composite score and the Wechsler subtest scores and IQs 12 were statistically significant (rs = .45 to .74). The new Wechsler scale appears to be a valid instrument for the 32 children (8-8 to 11-11) who were tested. PMID:8337322

Carvajal, H H; Hayes, J E; Lackey, K L; Rathke, M L; Wiebe, D A; Weaver, K A

1993-06-01

111

Biochemical Indices and Sensory Scores of Kunu-zaki Beverages Produced from Sprouted and Unsprouted Guinea Corn and Their Correlations  

Directory of Open Access Journals (Sweden)

Full Text Available Kunu-zaki beverage is a popular cereal-grain based non-alcoholic drink traditionally produced from sprouted cereal grains like sorghum, millet, maize or their mixtures. Unsprouted grains can also be used, thereby saving time spent during sprouting without compromising sensory property. The present study sought to investigate, in comparative terms, the biochemical indices and sensory scores of Kunu-zaki beverages produced from Sprouted Guinea Corn (SGC and Unsprouted Guinea Corn (USGC as well as establishing correlation between these parameters. Production of Kunu-zaki beverages from USGC and SGC was carried out using standard procedures. Samples of the beverages were analyzed for glucose, protein and hydrogen ion concentrations in concurrence with sensory evaluation scores. The results indicated that the Kunu-zaki beverages produced were of comparable (p>0.05 acidity values. Protein and glucose concentrations of Kunu-zaki beverage produced from SGC were significantly higher (p Kunu-zaki beverage produced from SGC gave: [protein] = 10.6±2.62 g L-1 and [glucose] = 500.0±4.90 mg dL-1, whereas beverage produced from USGC gave [protein] = 3.0 g L-1 and [glucose] = 335.3±2.8 mg dL-1. Sensory attributes of the beverages were not significantly different (p>0.05. The pH, mouthfeel, protein and glucose contents of the beverages had strong positive effects on their tastes. The protein content of Kunu-Zaki beverage produced from SGC had marginal effect on its taste. Although the levels of some biochemical parameters were reduced when Kunu-zaki beverage was produced from USGC, it did not affect its sensory property.

C.O. Ibegbulem

2014-01-01

112

Correlation of volumetric mismatch and mismatch of Alberta Stroke program Early CT scores on CT perfusion maps  

Energy Technology Data Exchange (ETDEWEB)

We aimed to determine if volumetric mismatch between tissue at risk and tissue destined to infarct on computed tomography perfusion (CTP) can be described by the mismatch of Alberta Stroke Program Early CT Score (ASPECTS). Forty patients with nonlacunar middle cerebral artery infarct <6 h old who had CTP on admission were retrospectively reviewed. Two raters segmented the lesion volume on mean transit time (MTT) and cerebral blood volume (CBV) maps using thresholds of >6 s and <2.0 mL per 100 g, respectively. Two other raters assigned ASPECTS to the same MTT and CBV maps while blinded to the volumetric data. Volumetric mismatch was deemed present if {>=}20%. ASPECTS mismatch (=CBV ASPECTS - MTT ASPECTS) was deemed present if {>=}1. Correlation between the two types of mismatches was assessed by Spearman's coefficient ({rho}). ROC curve analyses were performed to determine the optimal ASPECTS mismatch cut point for volumetric mismatch {>=}20%, {>=}50%, {>=}100%, and {>=}150%. Median volumetric mismatch was 130% (range 10.9-2,031%) with 31 (77.5%) being {>=}20%. Median ASPECTS mismatch was 2 (range 0-6) with 26 (65%) being {>=}1. ASPECTS mismatch correlated strongly with volumetric mismatch with {rho} = 0.763 [95% CI 0.585-0.870], p < 0.0001. Sensitivity and specificity for volumetric mismatch {>=}20% was 83.9% [95% CI 65.5-93.5] and 100% [95% CI 65.9-100], respectively, using ASPECTS mismatch {>=}1. Volumetric mismatch {>=}50%, {>=}100%, and {>=}150% were optimally identified using ASPECTS mismatch {>=}1, {>=}2, and {>=}2, respectively. On CTP, ASPECTS mismatch showed strong correlation to volumetric mismatch. ASPECTS mismatch {>=}1 was the optimal cut point for volumetric mismatch {>=}20%. (orig.)

Lin, Ke; Rapalino, Otto; Lee, Benjamin; Do, Kinh G.; Sussmann, Amado R.; Pramanik, Bidyut K. [NYU Medical Center/Bellevue Hospital, Department of Radiology, New York, NY (United States); Law, Meng [Mount Sinai Medical Center, Department of Radiology, New York, NY (United States)

2009-01-15

113

Correlation between serum ferritin levels and attention-deficit/hyperactivity disorder symptom scores in children based on the Abbreviated Conners Teachers Rating Scale  

Directory of Open Access Journals (Sweden)

Full Text Available Background Dopamine deficiency is thought to be one of the factors causing attention-deficit /hyperactivity disorder (ADHD in children. Iron contributes to the regulation of dopamine neurotransmitter activity, thus, iron deficiency has been associated with ADHD. Several studies have been conducted in other countries to assess for a correlation between serum ferritin levels and ADHD symptom scores, but with varied results. Objective To examine the relationship between iron deficiency and ADHD symptoms, in particular the correlation between serum ferritin levels and Abbreviated Conners Teachers Rrating Scale (ACTRS scores in children with ADHD. Methods This cross-sectional study was performed in children aged 5-12 years who were newly diagnosed with ADHD. Subjects were recruited from the Klinik Anakku Kelapa Gading, the Neurology Outpatient Clinic, the Growth and Development-Social Pediatrics Clinic, and the Integrated Child Clinic of Cipto Mangunkusumo Hospital. ADHD diagnoses were established using Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSMm-IV. Subjects’ parents and teachers were asked to complete the ACTRS instrument sheet. Venous blood specimens were obtained for peripheral blood and serum ferritin level tests. Results Of the 33 subjects recruited, 23 were male. Subjects’ ages ranged from 5-12 years, with a median age of onset of 4 (range 2-10 years. The combined type of ADHD (with inattention and hyperactivity-impulsivity was more commonly found (20/33 in our subjects. The mean serum ferritin was 51.31 (SD 27.7 ng/mL. Using 20 ng/mL as the serum ferritin cutoff value, 5/33 subjects were considered to be iron deficient. Median ACTRS score by parents and teachers were 15 and 15, respectively. Higher scores were found in the combined type subject group than in the inattention type subject group. Mmedian serum ferritin levels of the two ADHD type groups were similar. ACTRS scores of parents and teachers tended to be higher in the iron-deficient group (16 and 16, respectively than in the normal serum iron group (14.5 and 12.5, respectively. Serum ferritin level showed no correlation (r=-0.243; P=0.086 to the parents’ ACTRS score, and no correlation (r=-.057; P=0.377 to the teachers’ ACTRrS score. Conclusion Serum ferritin level showed no correlation to ACTRS scores of parents and teachers, respectively. However, the median ACTRS score was higher in the iron-deficiency group than in the normal iron status group, suggesting that there may be a qualitative relationship between iron deficiency and ADHD symptoms.

Intan Alita Putri Tumbelaka

2014-10-01

114

Entorhinal cortex volume measured with 3T MRI is positively correlated with the Wechsler memory scale-revised logical/verbal memory score for healthy subjects  

International Nuclear Information System (INIS)

Previous studies revealed a correlation between local brain volume and cognitive function. The aim of the present study was to investigate the correlation between local gray matter volume and the Wechsler Memory Scale-Revised (WMS-R) logical/verbal memory (WMS-R-verbal) score in healthy adults using a 3 Tesla magnetic resonance scanner and voxel-based morphometry (VBM). T1-weighted magnetic resonance images were obtained in 1,169 healthy adults. The T1-weighted images in native space were bias-corrected, spatially normalized, and segmented into gray matter, white matter, and cerebrospinal fluid images with Statistical Parametric Mapping 5. To investigate regionally the specific effects of the WMS-R-verbal score on the gray matter images, simple regression analysis was performed by VBM treating age, total intracranial volume, and gender as confounding covariates. A P value of less than 0.05 corrected with false discovery rate in voxel difference was considered to be statistically significant. Our study showed a significant positive correlation between the WMS-R-verbal score and the bilateral entorhinal cortex volume. In the right entorhinal, T value is 4.75, and the size of the clusters is 155 voxels. In the left entorhinal, T value is 4.08, and the size of the clusters is 23 voxels. A significant negative correlation was not found. To our knowledge, this is the first VBM study showing that entorhinal cortex volume is positively correlated with the WMS-R-verbal score fy correlated with the WMS-R-verbal score for healthy subjects. Therefore, in our structural neuroimaging study, we add evidence to the hypothesis that the entorhinal cortex is involved in verbal memory processing. (orig.)

115

Correlation of CT angiographic pulmonary artery obstruction scores with right ventricular dysfunction and clinical outcome in patients with acute pulmonary embolism  

Energy Technology Data Exchange (ETDEWEB)

Objective: To correlate CTA pulmonary artery obstruction scores (OS) with right ventricular dysfunction (RVD) and clinical outcome in patients with acute pulmonary embolism (PE). Materials and methods: In a prospective study of 50 patients (66 ± 12.9 years) with PE pulmonary artery OS (Qanadli, Mastora, and Mastora central) were assessed by two radiologists. To assess RVD all patients underwent echocardiography within 24 h. Furthermore, RVD on CT was assessed by calculating the right ventricular/left ventricular (RV/LV) diameter ratios on transverse (RV/LVtrans) and four-chamber views (RV/LV4ch) as well as the RV/LV volume ratio (RV/LVvol). OS were correlated with RVD and the occurrence of adverse clinical outcomes (defined as death, need for intensive care treatment, or cardiac insufficiency ?NYHA III). Results: Mean Mastora, Qanadli, and Mastora central OS were 26.4 ± 17.7, 12.6 ± 9.9 and 7.5 ± 9, respectively. Echocardiography demonstrated moderate and severe RVD in 10 and 5 patients, respectively. Patients with moderate and severe RVD showed significantly higher Mastora central scores than patients without RVD (14 ± 10.8 vs. 5.9 ± 7.8 [p = 0.05]; 17.6 ± 13.2 vs. 5.9 ± 7.8 [p = 0.038]). A relevant correlation (i.e. r ? 0.6) between OS and CT parameters for RVD were only found for the Mastora score and the Mastora central score (RV/LV4ch: r = 0.61 and 0.68, RV/LVvol: r = 0.61 and 0.6). 18 patients experienced an adverse clinical outcome. None of the OS differed significantly between patients with and without adverse clinical outcome. Conclusion: Pulmonary artery obstruction scores can differentiate between patients with and without RVD. However, in this study, obstruction scores were not correlated to adverse clinical outcome.

Apfaltrer, P., E-mail: paul.apfaltrer@medma.uni-heidelberg.de [Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim (Germany); Henzler, T.; Meyer, M. [Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim (Germany); Roeger, S.; Haghi, D.; Gruettner, J.; Süselbeck, T. [Department of Internal Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim (Germany); Wilson, R.B.; Schoepf, U.J. [Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Drive, MSC 226, Charleston, SC 29401 (United States); Schoenberg, S.O.; Fink, C. [Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim (Germany)

2012-10-15

116

Correlation of the modified Glasgow coma scale and Ramsay sedation scale scores with bispectral index monitoring in unconscious critically ill patients  

Directory of Open Access Journals (Sweden)

Full Text Available Objective: Monitoring critically ill patients with a decreased level of consciousness is challenging. It is suggested that bispectral index monitoring (BIS may be useful in the assessment of neurologic functions for critical care patients because simplicity is its essence. The aim of this randomised, prospective study was to assess the correlation of BIS with the Glasgow coma score modified by Cook and Palma (GCSC and Ramsay sedation scale (RSS for the measurement of neurologic status in critically ill patients. Material and Methods: Thirty-eight patients ranged from 15 to 65 years of age were evaluated for level of consciousness using BIS, GCSC and RSS in addition to standard intensive care monitorization. Spearman’s correlation coefficient was used to correlate the BIS scores with clinical scales. Results: BIS values correlated significantly with RSS (r= -0,388; p= 0,016 and GCSC (r= 0,629; p= 0,001. GCSC was significantly correlated with RSS (r= -0,518; p= 0,001. Conclusion: It was concluded that BIS is suitable for monitoring the neurologic status in unsedated critically ill patients. BIS was well correlated with the clinical assessment based on various scores.

Elif Bombac?

2005-01-01

117

7 CFR 1776.9 - Scoring applications.  

Science.gov (United States)

...2010-01-01 false Scoring applications. 1776... HOUSEHOLD WATER WELL SYSTEM GRANT PROGRAM HWWS Grants § 1776.9 Scoring applications. ...based on the following scoring criteria: (1...household water well systems and ground water....

2010-01-01

118

Could near-infrared Raman spectroscopy be correlated with the METAVIR scores in liver lesions induced by hepatitis C virus?  

Science.gov (United States)

The liver is responsible for several basic functions in human body how the syntheses of the most main proteins and degradation process of toxins, drugs and alcohols. In present days, the viral hepatitis C is one of the highest causes of chronic hepatic illness worldwide, affecting around 3% of the world population. The liver biopsy is considered the gold standard for diagnosing hepatic fibrosis; however, the biopsies may be questioned because of potential sampling error, morbidity, possible mortality and relatively high costs. Spectroscopy techniques such as Raman spectroscopy have been used for diagnosis of human tissues, with favorable results. Raman spectroscopy has been employed to distinguish normal from hepatic lesions through spectral features mainly of proteins, nucleic acids and lipids. In this study, eleven patients with diagnoses of chronic hepatitis C underwent hepatic biopsies having two hepatic fragments collected: one was scored through METAVIR system and the other one was submitted to near-infrared Raman spectroscopy using a dispersive spectrometer (830 nm wavelength, 300 mW laser power and 20 s exposure time). Five spectra were collected in each fragment and submitted to Principal Components Analysis (PCA). Results showed a good correlation between the Raman spectroscopy features and the stage of hepatic fibrosis and inflammation. PCA showed that samples with higher degree of fibrosis presented higher amount of protein features (collagen), whereas samples of higher degree of inflammation presented higher features of hemoglobin, in accordance to the expected evolution of the chronic hepatitis. It has been found an important biomarker for the beginning of hepatic lesion (quinone) with a spectral feature at 1595 cm-1.

Gaggini, Marcio Cesar Reino; Navarro, Ricardo Scarparo; Stefanini, Aline Reis; Sano, Rubens Sato; Silveira, Landulfo

2013-03-01

119

CORRELATION OF PEMPHIGUS VULGARIS ANTIBODY TITERS BY INDIRECT IMMUNOFLUORESCENCE WITH ACTIVITY OF DISEASE BASED ON PEMPHIGUS AREA AND ACTIVITY SCORE (PAAS  

Directory of Open Access Journals (Sweden)

Full Text Available Indirect immunofluorescence (IIF has been used to identify and measure autoantibody levels in pemphigus vulgaris but data about relationship between clinical severity of disease and antibody titers by IIF have been conflicting. We conducted this cross-sectional study to correlate the severity of oral and/or cutaneous involvement in patients with pemphigus vulgaris based on Pemphigus Area and Activity Score with IIF titers. Sixty-one new pemphigus vulgaris patients were included in this study. Human prepuce was used as substrate for IIF and assessment of disease severity was based on Pemphigus Area and Activity Score. The mean±SD age was 44.04±30.46 years, with a range of 18 to 79 years. IIF was positive in 56 (91.8% patients. There was a significant relationship between total disease score and IIF titers ((P<0.001. Also a significant relationship was found between skin score (P=0.04 and mucosal score (P=0.04 with IIF titers. Our results show that there is a significant relationship between disease activity based on Pemphigus Area and Activity Score and antibody titers by IIF. Further studies are recommended to determine the usefulness of this technique for monitoring disease.

H. Mortazavi

2008-06-01

120

Correlation between Bhalla score and spirometry in children and adolescents with Cystic Fibrosis / Correlação entre escore de Bhalla e espirometria em crianças e adolescentes com fibrose cística  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in portuguese Objetivo: correlacionar os achados da tomografia computadorizada de alta resolução (TCAR) do tórax, com base no escore de Bhalla, com os dados clínicos e a espirometria em crianças e adolescentes com fibrose cística (FC), além de estudar a concordância entre dois médicos radiologistas para o escor [...] e de Bhalla e suas categorias. Métodos: foram avaliados os prontuários e os exames de 23 pacientes do ambulatório. Os itens avaliados foram idade, peso, altura, escore Z altura/idade, escore Z peso/ idade, índice de massa corpórea (IMC), saturação de O2, espirometria e escore de Bhalla. Resultados: os pacientes avaliados tinham média de idade de 17,4±5,7 anos, sendo 15 do sexo feminino e 8 do sexo masculino. Houve boa correlação entre o escore de Bhalla e a espirometria (CVF-r = 0,718, p 70% já apresentavam alterações na nota final do escore de Bhalla. Na análise da concordância entre os examinadores, foi encontrado coeficiente kappa de 0,81 (p Abstract in english Objective: to correlate the findings of high resolution computed tomography of the chest based on the Bhalla score with the clinical data and spirometry in children and adolescents with cystic fibrosis, and to study the concordance between two radiologists for the Bhalla score and its categories. [...] Methods: we evaluated the medical records of 23 patients from the outpatient clinic. The items evaluated included age, weight, height, height/age Z-score, weight/age Z-score, body mass index (BMI), O2 saturation, spirometry and Bhalla score. Results: the patients had a mean age of 17.4 years ± 5.7 years, with fifteen females and eight males. There was good correlation between Bhalla score and spirometry (FVC-r =0.718, p 70% already had changes in their final Bhalla score. In the analysis of the concordance between the examiners a Kappa coefficient of 0.81 (p

Flavia Fajardo Linhares, Pereira; Cassio da Cunha, Ibiapina; Cristina Gonçalves, Alvim; Paulo Augusto Moreira, Camargos; Reginaldo, Figueiredo; Jesiana Ferreira, Pedrosa.

2014-06-01

121

Correlation of proton MR spectroscopic imaging with Galena's score based on step-section pathologic analysis after radical prostatectomy  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To determine whether hydrogen 1 magnetic resonance (MR) spectroscopic imaging can be used to predict aggressiveness of prostate cancer. Materials and Methods: All patients gave informed consent according to an institutionally approved research protocol. A total of 123 patients (median age, 58 years; age range, 40-74 years) who underwent endorectal MR imaging and MR spectroscopic imaging between January 2000 and December 2002 were included. MR imaging and spectroscopy were performed by using combined pelvic phased-array and endorectal probe. Water and lipids were suppressed, and phase-encoded data were acquired with 6.2-mm resolution. Voxels in the peripheral zone were considered suspicious for cancer if (Cho + Cr)/Cit was at least two standard deviations above the normal level, where Cho represents choline-containing compounds, Cr represents creatine and phosphocreatine, and Cit represents citrate. Correlation between metabolite ratio and four Gleason score groups identified at step-section pathologic evaluation (3 + 3, 3 + 4, 4 + 3, and > or =4 + 4) was assessed with generalized estimating equations. Results: Data from 94 patients were included. Pathologic evaluation was used to identify 239 lesions. Overall sensitivity of MR spectroscopic imaging was 56% for tumor detection, increasing from 44% in lesions with Gleason score of 3 + 3 to 89% in lesions with Gleason score greater than or equal to 4 + 4. There was a trend toward increasing (Cho + Cr)/Cit with increasing Gleason score in lesions identified correctly with MR spectroscopic imaging. Tumor volume assessed with MR spectroscopic imaging increased with increasing Gleason score. Conclusion: MR spectroscopic imaging measurement of prostate tumor (Cho + Cr)/Cit and tumor volume correlate with pathologic Gleason score. There is overlap between MR spectroscopic imaging parameters at various Gleason score levels, which may reflect methodologic and physiologic variations. MR spectroscopic imaging has potential in noninvasive assessment of prostate cancer aggressiveness. (author)

Zakian, K.L.; Sircar, K.; Hricak, H.; Chen, H.N.; Shukla-Dave, A.; Eberhardt, S.; Muruganandham, M.; Ebora, L.; Kattan, M.W.; Reuter, V.E.; Scardino, P.T.; Koutcher, J.A. [Memorial Sloan-Kettering Cancer Center, New York, NY (United States). Dept. of Medical Physics

2005-03-15

122

Entorhinal cortex volume measured with 3T MRI is positively correlated with the Wechsler memory scale-revised logical/verbal memory score for healthy subjects  

Energy Technology Data Exchange (ETDEWEB)

Previous studies revealed a correlation between local brain volume and cognitive function. The aim of the present study was to investigate the correlation between local gray matter volume and the Wechsler Memory Scale-Revised (WMS-R) logical/verbal memory (WMS-R-verbal) score in healthy adults using a 3 Tesla magnetic resonance scanner and voxel-based morphometry (VBM). T1-weighted magnetic resonance images were obtained in 1,169 healthy adults. The T1-weighted images in native space were bias-corrected, spatially normalized, and segmented into gray matter, white matter, and cerebrospinal fluid images with Statistical Parametric Mapping 5. To investigate regionally the specific effects of the WMS-R-verbal score on the gray matter images, simple regression analysis was performed by VBM treating age, total intracranial volume, and gender as confounding covariates. A P value of less than 0.05 corrected with false discovery rate in voxel difference was considered to be statistically significant. Our study showed a significant positive correlation between the WMS-R-verbal score and the bilateral entorhinal cortex volume. In the right entorhinal, T value is 4.75, and the size of the clusters is 155 voxels. In the left entorhinal, T value is 4.08, and the size of the clusters is 23 voxels. A significant negative correlation was not found. To our knowledge, this is the first VBM study showing that entorhinal cortex volume is positively correlated with the WMS-R-verbal score for healthy subjects. Therefore, in our structural neuroimaging study, we add evidence to the hypothesis that the entorhinal cortex is involved in verbal memory processing. (orig.)

Goto, Masami [University of Tokyo Hospital, Department of Radiological Technology, Graduate School of Medicine, Tokyo (Japan); Kanazawa University, Tsunomatyou, Graduate School of Medical Science, Kanazawa (Japan); Abe, Osamu; Takao, Hidemasa; Inano, Sachiko; Mori, Harushi; Kunimatsu, Akira; Ohtomo, Kuni [University of Tokyo Hospital, Department of Radiology, Tokyo (Japan); Miyati, Tosiaki [Kanazawa University, Tsunomatyou, Graduate School of Medical Science, Kanazawa (Japan); Yoshikawa, Takeharu; Hayashi, Naoto [University of Tokyo Hospital, Department of Computational Diagnostic Radiology and Preventive Medicine, Tokyo (Japan); Kabasawa, Hiroyuki [GE Healthcare, Japan Applied Science Laboratory, Hino (Japan); Aoki, Shigeki [Juntendo University, Department of Radiology, Tokyo (Japan); Ino, Kenji; Iida, Kyouhito; Yano, Keiichi [University of Tokyo Hospital, Department of Radiological Technology, Graduate School of Medicine, Tokyo (Japan)

2011-08-15

123

Correlation of emphysema score with perceived malignancy of pulmonary nodules: a multi-observer study using the LIDC-IDRI CT lung database  

Science.gov (United States)

Presence of emphysema is recognized to be one of the single most significant risk factors in risk models for the prediction of lung cancer. Therefore, an automatically computed emphysema score would be a prime candidate as an additional numerical feature for computer aided diagnosis (CADx) for indeterminate pulmonary nodules. We have applied several histogram-based emphysema scores to 460 thoracic CT scans from the IDRI CT lung image database, and analyzed the emphysema scores in conjunction with 3000 nodule malignancy ratings of 1232 pulmonary nodules made by expert observers. Despite the emphysema being a known risk factor, we have not found any impact on the readers' malignancy rating of nodules found in a patient with higher emphysema score. We have also not found any correlation between the number of expert-detected nodules in a patient and his emphysema score, or the relative craniocaudal location of the nodules and their malignancy rating. The inter-observer agreement of the expert ratings was excellent on nodule diameter (as derived from manual delineations), good for calcification, and only modest for malignancy and shape descriptions such as spiculation, lobulation, margin, etc.

Wiemker, Rafael; Bülow, Thomas; Blaffert, Thomas; Dharaiya, Ekta

2009-02-01

124

Correlation of Revised Trauma Score with Mortality Rate of Traumatic Patients within the First 24 hours of Hospitalization  

Directory of Open Access Journals (Sweden)

Full Text Available Background: Trauma is a major health problem throughout the world, leading to death and disability especially in the first four decades of victims’ life. In Iran also, accident-related death has a critical situation with an increasing rate of 10-15% per year. The aim of this study was to determine the relationship between revised trauma score and mortality rate of traumatic patients within the first 24 h of hospitalization. Materials and Methods: A prospective cross-sectional study was conducted to investigate the association between revised trauma score and the mortality rate of traumatic patients within the first 24 h of hospitalization on 240 traumatic patients admitted to Khatam al-Anbia hospital. The obtained data were analyzed with SPSS software-15, using logistic regression, chi-square, and descriptive statistics. Results: Seventy four point tow percent of patients were referred due to accident, of which 38.3% had multiple traumas. Fifty point eight percent of traumatic patients died within the first 24 h of hospitalization. The minimum and maximum revised trauma score in injured patients were 7 and 12, respectively. Also, 80% of mortality was seen in victims with a score of 9-10. Both the ?2 test and logistic regression showed a significant relationship between the first revised trauma score and the mortality rate of traumatic patients within the first 24 h of hospitalization (p=0.001. Conclusion: The results of this study indicate that the revised trauma score can be used as a tool to predict the mortality rate of traumatic patients.

Nastaran Heydari-Khayat

2014-12-01

125

The Correlation of Brody High Resolution Computed Tomography Scoring System with Clinical Status and Pulmonary Function Test in Patients with Cystic Fibrosis  

OpenAIRE

Background: To reduce the mortality and morbidity rates of cystic fibrosis (CF) patients, and to have an effective clinical management, it is important to monitor the progression of the disease. The aim of this study was to evaluate the progression of lung disease in CF patients by means of assessing the correlation of the CT scoring system with clinical status and pulmonary function test at the Pediatric Pulmonary Ward of Masih Daneshvari Hospital in 2008. Methods: Pulmonary high resolution ...

Soheila Khalilzadeh; Shahram Kahkouee; Maryam Hassanzad; Nazanin Parsanejad; Nooshin Baghaie; Mohammad Reza Bloorsaz

2011-01-01

126

CORRELATION OF PEMPHIGUS VULGARIS ANTIBODY TITERS BY INDIRECT IMMUNOFLUORESCENCE WITH ACTIVITY OF DISEASE BASED ON PEMPHIGUS AREA AND ACTIVITY SCORE (PAAS)  

OpenAIRE

Indirect immunofluorescence (IIF) has been used to identify and measure autoantibody levels in pemphigus vulgaris but data about relationship between clinical severity of disease and antibody titers by IIF have been conflicting. We conducted this cross-sectional study to correlate the severity of oral and/or cutaneous involvement in patients with pemphigus vulgaris based on Pemphigus Area and Activity Score with IIF titers. Sixty-one new pemphigus vulgaris patients were included in this study...

Mortazavi, H.; Kiavash, K.; Chams-davatchi, N. Esmaili C.

2008-01-01

127

Does Council Tax Valuation Band (CTVB correlate with Under-Privileged Area 8 (UPA8 score and could it be a better 'Jarman Index'?  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Widespread scepticism persists on the use of the Under-Privileged Area (UPA8 score of Jarman in distributing supplementary resources to so-attributed 'deprived' UK general practices. The search for better 'needs' markers continues. Having already shown that Council Tax Valuation Band (CTVB is a predictor of UK GP workload, we compare, here, CTVB of residence of a random sample of patients with their respective 'Jarman' scores. Methods Correlation coefficient is calculated between (i the CTVB of residence of a randomised sample of patients from an English general practice and (ii the UPA8 scores of the relevant enumeration districts in which they live. Results There is a highly significant correlation between the two measures despite modest study size of 478 patients (85% response. Conclusions The proposal that CTVB is a marker of deprivation and of clinical demand should be examined in more detail: it correlates with 'Jarman', which is already used in NHS resource allocation. But unlike 'Jarman', CTVB is simple, objective, and free of the problems of Census data. CTVB, being household-based, can be aggregated at will.

Taylor Gordon

2001-11-01

128

Segmented corpus callosum diffusivity correlates with the Expanded Disability Status Scale score in the early stages of relapsing-remitting multiple sclerosis  

Science.gov (United States)

OBJECTIVE: The aim of this study was to characterize the microscopic damage to the corpus callosum in relapsing-remitting multiple sclerosis (RRMS) with diffusion tensor imaging and to investigate the correlation of this damage with disability. The diffusion tensor imaging parameters of fractional anisotropy and mean diffusivity provide information about the integrity of cell membranes, offering two more specific indices, namely the axial and radial diffusivities, which are useful for discriminating axon loss from demyelination. METHOD: Brain magnetic resonance imaging exams of 30 relapsing-remitting multiple sclerosis patients and 30 age- and sex-matched healthy controls were acquired in a 3T scanner. The axial diffusivities, radial diffusivities, fractional anisotropy, and mean diffusivity of five segments of the corpus callosum, correlated to the Expanded Disability Status Scale score, were obtained. RESULTS: All corpus callosum segments showed increased radial diffusivities and mean diffusivity, as well as decreased fractional anisotropy, in the relapsing-remitting multiple sclerosis group. The axial diffusivity was increased in the posterior midbody and splenium. The Expanded Disability Status Scale scores correlated more strongly with axial diffusivities and mean diffusivity, with an isolated correlation with radial diffusivities in the posterior midbody of the corpus callosum. There was no significant correlation with lesion loads. CONCLUSION: Neurological dysfunction in relapsing-remitting multiple sclerosis can be influenced by commissural disconnection, and the diffusion indices of diffusion tensor imaging are potential biomarkers of disability that can be assessed during follow-up. PMID:24037007

de Medeiros Rimkus, Carolina; de Faria Junqueira, Thiago; Callegaro, Dagoberto; Otaduy, Maria Concepción García; da Costa Leite, Claudia

2013-01-01

129

Segmented corpus callosum diffusivity correlates with the Expanded Disability Status Scale score in the early stages of relapsing-remitting multiple sclerosis  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in english OBJECTIVE: The aim of this study was to characterize the microscopic damage to the corpus callosum in relapsing-remitting multiple sclerosis (RRMS) with diffusion tensor imaging and to investigate the correlation of this damage with disability. The diffusion tensor imaging parameters of fractional [...] anisotropy and mean diffusivity provide information about the integrity of cell membranes, offering two more specific indices, namely the axial and radial diffusivities, which are useful for discriminating axon loss from demyelination. METHOD: Brain magnetic resonance imaging exams of 30 relapsing-remitting multiple sclerosis patients and 30 age- and sex-matched healthy controls were acquired in a 3T scanner. The axial diffusivities, radial diffusivities, fractional anisotropy, and mean diffusivity of five segments of the corpus callosum, correlated to the Expanded Disability Status Scale score, were obtained. RESULTS: All corpus callosum segments showed increased radial diffusivities and mean diffusivity, as well as decreased fractional anisotropy, in the relapsing-remitting multiple sclerosis group. The axial diffusivity was increased in the posterior midbody and splenium. The Expanded Disability Status Scale scores correlated more strongly with axial diffusivities and mean diffusivity, with an isolated correlation with radial diffusivities in the posterior midbody of the corpus callosum. There was no significant correlation with lesion loads. CONCLUSION: Neurological dysfunction in relapsing-remitting multiple sclerosis can be influenced by commissural disconnection, and the diffusion indices of diffusion tensor imaging are potential biomarkers of disability that can be assessed during follow-up.

Carolina de Medeiros, Rimkus; Thiago de Faria, Junqueira; Dagoberto, Callegaro; Maria Concepcion Garcia, Otaduy; Claudia da Costa, Leite.

1115-11-01

130

Vacuolization, Dilatation, Hyaline Cast, Debris or Degeneration: Which One Is the Most Correlated Item to Score the Kidney Damage Pathologically in Cisplatin Induced Nephrotoxicity Model?  

Science.gov (United States)

Background Nephrotoxicity is characterized and scored by many parameters such as vacuolization, dilatation, hyaline cast, debris or degeneration in injured renal tissue. In this short report, we attempt to find, the most correlated parameters with kidney tissue pathology damage score (PDS) in Cisplatin-induced nephrotoxicity. Method A total of 207 normal and toxic rats’ kidney tissue (induced by Cisplatin) were evaluated for toxicity intensity by two methods. In the first method, the tissue damage was scored from 0 to 4, and in the second method the percentage of vacuolization, dilatation, hyaline cast, debris or degeneration were determined. The data was analyzed using stepwise discriminant function and regression analysis. Results The variables having the higher discriminant function coefficient were hyaline cast, dilatation, and degeneration. The linear regression model and the prediction function to determine the kidney tissue PDS were generated as below. PDS = 0.445 + 0.035 × hyaline cast + 0.013 × dilatation + 0.020 × degeneration Conclusion According to this finding it is suggested that presence of hyaline cast and dilatation, and then degeneration in the sample of toxic renal tissue are the most important item to score the damage intensity. PMID:24350092

Ashrafi, Farzaneh; Nematbakhsh, Mehdi; Nasri, Hamid; Talebi, Ardeshir; Hosseini, Sayed Mohsen; Ashrafi, Mehdi

2013-01-01

131

Correlation of Revised Trauma Score with Mortality Rate of Traumatic Patients within the First 24 hours of Hospitalization  

OpenAIRE

Background: Trauma is a major health problem throughout the world, leading to death and disability especially in the first four decades of victims’ life. In Iran also, accident-related death has a critical situation with an increasing rate of 10-15% per year. The aim of this study was to determine the relationship between revised trauma score and mortality rate of traumatic patients within the first 24 h of hospitalization. Materials and Methods: A prospective cross-sectional study was c...

Nastaran Heydari-Khayat; Hassan Sharifipoor; Mohammad Ali Rezaei; Neda Mohammadinia; Fatemeh Darban

2014-01-01

132

WHO-histological criteria for myeloproliferative neoplasms: reproducibility, diagnostic accuracy and correlation with gene mutations and clinical outcomes.  

Science.gov (United States)

Bone marrow histology is included in the diagnostic criteria of myeloproliferative neoplasms (MPNs). However, some concerns have emerged about its reproducibility. To evaluate the diagnostic accuracy of histology and to assess its correlation with presence of mutations and clinical outcomes, two pathologists reviewed the bone marrow biopsies corresponding to 211 patients with MPN. Despite the low agreement in the evaluation of individual histopathological characteristics, the concordance among pathologists when establishing the diagnosis was good (Kappa index 0·67). The specificity of histology was 100%, 98·5% and 98% in polycythaemia vera (PV), essential thrombocythaemia (ET) and primary myelofibrosis (PMF), respectively, whereas the sensitivity of histological diagnosis was low in PV and ET (32·5% and 54% respectively) and acceptable in PMF (75%). Thirteen out of 146 (9%) patients with clinical ET were diagnosed as prefibrotic PMF. No histological agreement or MPN otherwise unspecified was more frequently observed in JAK2 V617F-positive ET than in CALR-mutated cases, whereas megakaryocytic abnormalities and prefibrotic PMF were more frequently observed in CALR-mutated ET. In conclusion, histological criteria of MPN have a limited diagnostic accuracy due to low sensitivity. Patients with JAK2 V617F-positive MPN have a heterogeneous histology while CALR-positive ET is associated with megakaryocyte abnormalities and prefibrotic PMF. PMID:24957246

Alvarez-Larrán, Alberto; Ancochea, Agueda; García, Mar; Climent, Fina; García-Pallarols, Francesc; Angona, Anna; Senín, Alicia; Barranco, Carlos; Martínez-Avilés, Luz; Serrano, Sergio; Bellosillo, Beatriz; Besses, Carlos

2014-09-01

133

Diagnostic yield of MRI for audiovestibular dysfunction using contemporary referral criteria: correlation with presenting symptoms and impact on clinical management  

Energy Technology Data Exchange (ETDEWEB)

Aim: To investigate the diagnostic yield of T2-weighted magnetic resonance imaging (MRI) screening for vestibular schwannoma and other relevant conditions in the setting of audiovestibular symptoms, given the more liberal contemporary referral criteria. To determine whether presenting clinical symptoms correlate with imaging outcome in order to guide future protocols for MRI referral. Materials and methods: Eight hundred and eighty-one consecutive MRI examinations performed in patients with audiovestibular dysfunction were reviewed. Clinical indications and findings were recorded. Case notes were reviewed in patients with positive imaging findings. Two-way, cross-tabulation, Chi-square analysis was performed to assess the relationship between presenting symptoms and imaging outcome. Results: Twelve of the 881 (1.4%) were positive for vestibular schwannoma. A further four of 881 (0.4%) revealed other relevant conditions. Incidental conditions, felt to be irrelevant to the presenting symptoms, were noted in 12 of the 881 (1.4%). In all 12 cases that were positive for vestibular schwannoma, either tinnitus or hearing loss was present. Conclusion: The yield for T2-weighted MRI to diagnose vestibular schwannoma and other relevant retrocochlear conditions was lower than for previous studies, which is likely to reflect trends in referral criteria. No single audiovestibular symptom or combination of symptoms is a statistically significant predictor of imaging outcome.

Vandervelde, C. [Department of Radiology, Guy' s and St Thomas' NHS Foundation Trust (United Kingdom)], E-mail: clivevandervelde@gmail.com; Connor, S.E.J. [Department of Radiology, Guy' s and St Thomas' NHS Foundation Trust (United Kingdom); Department of Neuroradiology, King' s College Hospital NHS Foundation Trust, London (United Kingdom)

2009-02-15

134

Diagnostic yield of MRI for audiovestibular dysfunction using contemporary referral criteria: correlation with presenting symptoms and impact on clinical management  

International Nuclear Information System (INIS)

Aim: To investigate the diagnostic yield of T2-weighted magnetic resonance imaging (MRI) screening for vestibular schwannoma and other relevant conditions in the setting of audiovestibular symptoms, given the more liberal contemporary referral criteria. To determine whether presenting clinical symptoms correlate with imaging outcome in order to guide future protocols for MRI referral. Materials and methods: Eight hundred and eighty-one consecutive MRI examinations performed in patients with audiovestibular dysfunction were reviewed. Clinical indications and findings were recorded. Case notes were reviewed in patients with positive imaging findings. Two-way, cross-tabulation, Chi-square analysis was performed to assess the relationship between presenting symptoms and imaging outcome. Results: Twelve of the 881 (1.4%) were positive for vestibular schwannoma. A further four of 881 (0.4%) revealed other relevant conditions. Incidental conditions, felt to be irrelevant to the presenting symptoms, were noted in 12 of the 881 (1.4%). In all 12 cases that were positive for vestibular schwannoma, either tinnitus or hearing loss was present. Conclusion: The yield for T2-weighted MRI to diagnose vestibular schwannoma and other relevant retrocochlear conditions was lower than for previous studies, which is likely to reflect trends in referral criteria. No single audiovestibular symptom or combination of symptoms is a statistically significant predictor of imaging outcomecant predictor of imaging outcome

135

Computer-Aided Quantification of Interstitial Lung Disease from High Resolution Computed Tomography Images in Systemic Sclerosis: Correlation with Visual Reader-Based Score and Physiologic Tests  

Science.gov (United States)

Objective. To evaluate the performance of a computerized-aided method (CaM) for quantification of interstitial lung disease (ILD) in patients with systemic sclerosis and to determine its correlation with the conventional visual reader-based score (CoVR) and the pulmonary function tests (PFTs). Methods. Seventy-nine patients were enrolled. All patients underwent chest high resolution computed tomography (HRCT) scored by two radiologists adopting the CoVR. All HRCT images were then analysed by a CaM using a DICOM software. The relationships among the lung segmentation analysis, the readers, and the PFTs results were calculated using linear regression analysis and Pearson's correlation. Receiver operating curve analysis was performed for determination of CaM extent threshold. Results. A strong correlation between CaM and CoVR was observed (P < 0.0001). The CaM showed a significant negative correlation with forced vital capacity (FVC) (P < 0.0001) and the single breath carbon monoxide diffusing capacity of the lung (DLco) (P < 0.0001). A CaM optimal extent threshold of 20% represented the best compromise between sensitivity (75.6%) and specificity (97.4%). Conclusions. CaM quantification of SSc-ILD can be useful in the assessment of extent of lung disease and may provide reliable tool in daily clinical practice and clinical trials.

Salaffi, Fausto; Carotti, Marina; Bosello, Silvia; Bichisecchi, Elisabetta; Giuseppetti, Gianmarco; Ferraccioli, Gianfranco

2015-01-01

136

Criteria of GenCall score to edit marker data and methods to handle missing markers have an influence on accuracy of genomic predictions  

DEFF Research Database (Denmark)

The aim of this study was to investigate the effect of different strategies for handling low-quality or missing data on prediction accuracy for direct genomic values of protein yield, mastitis and fertility using a Bayesian variable model and a GBLUP model in the Danish Jersey population. The data contained 1071 Jersey bulls that were genotyped with the Illumina Bovine 50K chip. After preliminary editing, 39227 SNP remained in the dataset. Four methods to handle missing genotypes were: 1) BEAGLE: missing markers were imputed using Beagle 3.3 software, 2) COMMON: missing genotypes at a locus were replaced by the most common genotype at this locus observed in the marker data, 3) EX-ALLELE: missing marker genotypes at a locus were treated as an extra allele, and 4) POP-EXP: missing genotypes at a locus were replaced with population expectation at this locus. It was shown that among the methods used in this study, imputation with Beagle was the best approach to handle missing genotypes. Treating missing markers as a pseudo-allele, replacing missing markers with a population average or substituting the most common alleles each reduced the accuracy of genomic predictions. The results from this study suggest that missing genotypes should be imputed in order to improve genomic prediction. Editing the marker data with stringent threshold on GenCall (GC) scores and then imputing the discarded genotypes did not lead to higher accuracy. All marker genotypes with a GC score over 0.15 should be retained for genomic prediction

Edriss, Vahid; Guldbrandtsen, Bernt

2013-01-01

137

Routine Assessment of Patient Index Data 3 score (RAPID3) correlates well with Bath Ankylosing Spondylitis Disease Activity index (BASDAI) in the assessment of disease activity and monitoring progression of axial spondyloarthritis.  

Science.gov (United States)

Routine Assessment of Patient Index Data 3 (RAPID3) is a composite index, very useful for assessment of disease activity of various rheumatic diseases including RA. If RAPID3 can also reliably measure disease activity in axial spondyloarthritis (axSpA), it may prove to be a practical and effective quantitative assessment tool in busy practices. We studied the association of RAPID3 with Bath Ankylosing Spondylitis Disease Activity Index (BASDAI). Patients with Ankylosing Spondylitis (AS) seen from 2007 to 2012 were classified as having AS or non-radiographic axial spondyloarthritis (nr-axSpA) using modified New York criteria and Assessment of SpondyloArthritis International Society criteria, respectively. Patients with simultaneous BASDAI and RAPID3 scores were enrolled (N?=?112; 105 with AS, seven with nr-axSpA). Multiple regression and nonparametric receiver operating characteristics were used. Baseline mean (SD) BASDAI and RAPID3 were 4.2 (2.5) and 3.8 (2.3), respectively. Multiple linear regressions modeled a quadratic relationship between BASDAI and RAPID3 for 321 observations in 112 patients with axSpA (1) cross-sectionally: BASDAI predicted by RAPID3 (??=?1.171; s.e.?=?0.113, p?scores of 2, 4, and 6: 1.40 (85.8 %), 3.33 (81.9 %), and 5.43 (87.1 %), respectively. RAPID3 correlates well with BASDAI in monitoring axSpA patients (including AS) in cross-sectional and longitudinal follow-up. Since it also correlates with measures of disease activity of other rheumatic diseases including RA, RAPID3 could be an attractive measure for assessing and monitoring disease activity of several conditions seen in busy rheumatology practices. PMID:25421013

Danve, Abhijeet; Reddy, Anusha; Vakil-Gilani, Kiana; Garg, Neha; Dinno, Alexis; Deodhar, Atul

2015-01-01

138

Correlações genéticas entre escores visuais e características reprodutivas em bovinos Nelore usando inferência bayesiana / Genetic correlations between visual scores and reproductive traits in Nelore cattle using Bayesian inference  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese O objetivo deste trabalho foi estimar a herdabilidade e as correlações genéticas entre escores visuais e características reprodutivas de animais da raça Nelore. As características avaliadas foram: precocidade, musculatura, e escores de conformação à desmama (PD, MD e CD, respectivamente) e ao sobrea [...] no (PS, MS e CS, respectivamente); idade ao primeiro parto (IPP); e perímetro escrotal (PE). Foram utilizadas informações de 66.244 animais, nascidos entre 1990 e 2006. Os parâmetros genéticos foram estimados em análises bicaracterísticas, com inferência bayesiana. Foi utilizado um modelo linear para IPP e PE, e um modelo não linear ("threshold") para os escores visuais. As herdabilidades estimadas foram: CD, 0,19±0,02; PD, 0,23±0,02; MD, 0,20±0,02; CS, 0,26±0,01; PS, 0,33±0,02; MS, 0,32±0,02; IPP, 0,16±0,03; e PE, 0,36±0,02. As correlações genéticas estimadas entre os escores visuais e IPP foram negativas, de -0,18±0,03 a -0,29±0,02. Correlações genéticas positivas foram obtidas entre os escores visuais e o PE, de 0,19±0,01 a 0,31±0,01. A seleção de animais com os maiores escores visuais, principalmente ao sobreano, permite melhorar o desempenho reprodutivo dos rebanhos Abstract in english The aim of this work was to estimate the heritability and the genetic correlations between visual scores and reproductive traits of Nelore cattle. The traits evaluated were: finishing, muscling, and conformation scores at weaning (PD, MD, and CD, respectively) and yearling (PS, MS and CS, respective [...] ly); age at the first calving (IPP) and scrotal circumference (PE). The records of 66,244 animals born between 1990 and 2006 were used. The genetic parameters were estimated using bi-trait animal analyses with Bayesian inference. A linear model for IPP and PE and a nonlinear (threshold) model for visual scores were used. The heritability estimates were: CD, 0.19±0.02; PD, 0.23±0.02; MD, 0.20±0.02; CS, 0.26±0.01; PS, 0.33±0.02; MS, 0.32±0.02; IPP, 0.16±0.03; and PE, 0.36±0.02. Genetic correlation estimates between visual scores and IPP were negative, varying from -0.18±0.03 to -0.29±0.02. Positive genetic correlations were obtained between the visual scores and PE, from 0.19±0.01 to 0.31±0.01. Animal selection with the highest visual scores, mainly those taken after the yearling age, allows to improve herd reproductive traits

Arione Augusti, Boligon; Lucia Galvão de, Albuquerque.

1412-14-01

139

Reproducibility of a scoring system for gram stain diagnosis of bacterial vaginosis.  

OpenAIRE

A total of 225 pairs of duplicate Gram-stained slides from three hospitals in Jakarta were evaluated independently by a local (University of Indonesia, Jakarta) and a referral (University of Washington, Seattle) laboratory by the new scoring criteria proposed by Nugent et al. The correlation coefficients of the duplicate Gram stain scores ranged from 0.65 to 0.83. The kappa statistics for the bacterial vaginosis category (no, score of 0 to 6; yes, score of 7 to 10) ranged from 0.62 to 0.77. T...

Joesoef, M. R.; Hillier, S. L.; Josodiwondo, S.; Linnan, M.

1991-01-01

140

A new scoring method with magnetic resonance imagings for prediction of the postoperative results in cervical myelopathy  

International Nuclear Information System (INIS)

An evaluating method that uses scoring of preoperative magnetic resonance imagings (MRI) (preoperative MRI cumulative score) was devised to predict the postoperative results of dilation of the spinal canal for cervical spondylotic myelopathy. The usefulness of the method is reported. The subjects were 38 patients, and the mean preoperative MRI cumulative score was 9.2 points. The coefficient of correlation between the score and the postoperative improvement rate according to the criteria for results of treatment for spondylotic cervical myelopathy of the neck (established by the Japanese Orthopaedic Association) was -0.462, a significantly negative correlation. (author)

141

Heritabilities and genetic correlations of body condition score and muscularity with productive traits and their trend functions in Italian Simmental cattle  

Directory of Open Access Journals (Sweden)

Full Text Available With the aim to study the genetics of energy and muscle balance in the Italian Simmental breed, the objectives of this study were: i the estimation of the genetic parameters for body condition score (BCS and muscularity (MU score; ii the estimation of genetic correlations of BCS and MU with productive traits; iii the estimation of the expected pattern of BCS and MU over lactation. A total of 47,839 records of first-parity lactating cows, collected from 1999 to 2007 in 2794 herds, were used. Two-trait animal models were analyzed using restricted maximum likelihood (REML procedures to estimate (covariance components. The expected patterns of BCS and MU along the lactation of first parity cows were estimated from the solutions of DIM fixed effect obtained from an univariate mixed model for both the traits. The heritability estimated was 0.18 for BCS, 0.38 for MU, and ranged from 0.13 to 0.18 for yield traits. The genetic correlations between BCS, MU and yield traits were negative (-0.17 to -0.63. The genetic correlation between BCS and MU was strongly positive (0.88, indicating that cows that genetically tend to have high BCS are more likely to have high values of MU. The genetic parameters estimated suggested that selection for BCS and MU in dual purpose breeds may be possible, and BCS may indirectly improve MU. The expected patterns for BCS and MU showed the trend of these two traits along the lactation and can help farmers in planning the best management of the lactating cows.

Alessandro Bagnato

2013-04-01

142

Assessment of the metabolic flow phenotype of primary colorectal cancer: correlations with microvessel density are influenced by the histological scoring method  

Energy Technology Data Exchange (ETDEWEB)

To investigate how the histological scoring of microvessel density affects correlations between integrated {sup 18}F-FDG-PET/perfusion CT parameters and CD105 microvessel density. A total of 53 patients were enrolled from 2007 to 2010. Integrated {sup 18}F-FDG-PET/perfusion CT was successful in 45 patients, 35 of whom underwent surgery without intervening treatment. Tumour SUV{sub max}, SUV{sub mean} and regional blood flow (BF) were derived. Immunohistochemical staining for CD105 expression and analysis were performed for two hot spots, four hot spots and the Chalkley method. Correlations between metabolic flow parameters and CD105 expression were assessed using Spearman's rank correlation. Mean (SD) for tumour size was 38.5 (20.5) mm, for SUV{sub max}, SUV{sub mean} and BF it was 19.1 (4.5), 11.6 (2.5) and 85.4 (40.3) mL/min/100 g tissue, and for CD105 microvessel density it was 71.4 (23.6), 66.8 (22.9) and 6.18 (2.07) for two hot spots, four hot spots and the Chalkley method, respectively. Positive correlation between BF and CD105 expression was modest but higher for Chalkley than for four hot spots analysis (r = 0.38, P = 0.03; r = 0.33, P = 0.05, respectively). There were no significant correlations between metabolic parameters (SUV{sub max} or SUV{sub mean}) and CD105 expression (r = 0.08-0.22, P = 0.21-0.63). The histological analysis method affects correlations between tumour CD105 expression and BF but not SUV{sub max} or SUV{sub mean}. (orig.)

Goh, Vicky [King' s College London, Division of Imaging Sciences and Biomedical Engineering, London (United Kingdom); Rodriguez-Justo, Manuel [University College Hospital, Department of Histopathology, London (United Kingdom); Engledow, Alec; Peck, Jacqui [University College Hospital, Department of Surgery, London (United Kingdom); Shastry, Manu; Endozo, Raymondo; Meagher, Marie; Groves, Ashley M. [University College Hospital, Institute of Nuclear Medicine, London (United Kingdom); Taylor, Stuart A.; Halligan, Steve [University College Hospital, Specialist Radiology, London (United Kingdom)

2012-08-15

143

Bone mineral density (BMD) composite index scores developed from bone densitometry (DXA and QCT) simplifies correlative and predictive analyses in adolescent's bone health  

International Nuclear Information System (INIS)

Full text: Introduction and aim. Adolescence is a critical period to accumulate 50-70% of adult's bone mass. Hence, precise bone mass determination is important to monitor BMD development among adolescents in health and disease. It is uncertain at which skeletal site BMD is best predicted by bone-mass determinants. Besides, BMD measured at different sites of an individual can be condensed into a composite-index-score to simplify correlation, outcome prediction and data interpretation. This study describes the development of BMD composite index scores (BMD-CISs) to correlate with bone growth determinants in adolescents. Subjects and methods BMD measurements using DXA: Norland-XR36 (spine, femoral-neck, trochanter and Ward's triangle) and pQCT: Denisiscan-2000 (distal-radius and tibia) were obtained from 101 healthy girls aged 12-15 years to develop the BMD-CISs. Adolescent bone growth predictors (weight, height, pubertal-status, weight-bearing physical-exercise and bone-turnover markers) were evaluated to correlate with BMD-CISs. Factor and principle-component analyses were used to examine the internal structure of 11 BMD skeletal sites and variables, and to create new BMD-CISs which summarize the characteristics of parent BMD-variables. Correlations between the BMD-CISs and parent BMD variables were performed. Univariate and multivariate analysis were performed to associate BMD-CISs with bone growth predictors for examining the strength of correlations and predictionse strength of correlations and predictions when compared with the original BMD variables. Results. Two independent DXA-generated BMD-CIS and pQCT-generated BMD-CIS were obtained to summarize the 11 original BMD variables. Each BMD-CIS correlated highly with respective DXA or pQCT variable (r=0.32-0.92; P<0.05 - P<0.001). DXA generated BMD-CIS (r=0.24 - 0.73; P<0.05-P<0.001) and pQCT-generated BMD-CIS (r=0.24-0.39; P<0.05-P<0.001) were significantly correlated with most bone growth predictors. In multiple regression analysis, R-square of DXA-BMD-CIS (66.4% vs. 36.3%-66.1%) and pQCT-BMD- CIS (25.1% vs. 12.2%-42.2%) have similar predicting values when compared with parent BMD variables demonstrated that the two new BMD-CISs summarized well the characteristics of the parent BMD variables. Furthermore, areal spinal BMD (by DXA) and volumetric tibial integral BMD (by pQCT) were the BMD sites better predicted by bone-mass determinants (R-squares 0.6-0.8) in multiple regression analysis. Discussion and conclusions. The newly developed BMD-CISs correlated well with original variables and have similar predicting powers when compared with the original BMD variables. The use of BMD-CISs would reduce workload of data analysis and simplify correlation and comparisons between multiple BMD measurements and other predicting variables. Identification of 1-2 skeletal sites better associated with health predictive variables could help reduce the number of skeletal sites for BMD measurement, thus, reducing subject's exposure to unnecessary X ray irradiation. (author)

144

A Comparison of Two Scoring Methods for an Automated Speech Scoring System  

Science.gov (United States)

This paper compares two alternative scoring methods--multiple regression and classification trees--for an automated speech scoring system used in a practice environment. The two methods were evaluated on two criteria: construct representation and empirical performance in predicting human scores. The empirical performance of the two scoring models…

Xi, Xiaoming; Higgins, Derrick; Zechner, Klaus; Williamson, David

2012-01-01

145

Correlations among GPA and scores on the Spanish version of WISC-R and the Woodcock-Johnson Achievement subtests for 10- to 12-year-old Puerto Rican children.  

Science.gov (United States)

The purpose of this study was to explore the correlations among GPA, the Spanish version of the WISC-R, and the Woodcock Johnson Achievement subtests for a group of Puerto Rican children. The tests were administered to a sample of 32 children between the ages of 10 to 12 yr. in Grade 4. Pearson correlations between the Verbal, Performance, and Full Scale scaled scores in the WISC-R (Spanish Edition) ranged between .37 to .83. Correlations between subtests of the Woodcock-Johnson Achievement Test ranged from .26 to .70. The moderate correlation between the Total scaled scores on the Woodcock-Johnson and the scaled scores of the Performance, Verbal, and Full Scales of the Spanish WISC-R is indicative of the value of these Spanish-language instruments in diagnosing the intellectual and academic performance of Spanish-speaking populations in the United States. PMID:2349349

Rodriguez, V L; Prewitt Diaz, J O

1990-04-01

146

Prognostic Correlates of Combined Coronary Flow Reserve Assessment on Left Anterior Descending and Right Coronary Artery in Patients with Negative Stress Echocardiography by Wall Motion Criteria.  

OpenAIRE

Aims: To assess the prognostic correlates of Doppler echocardiographically derived coronary flow reserve (CFR) on two coronaries in patients with negative stress echo. Vasodilator stress echocardiography allows dual imaging of regional wall motion and CFR both on left anterior descending (LAD) and right coronary artery (RCA). Methods: The study group comprised 460 patients with known or suspected coronary artery disease and negative stress echo by wall motion criteria. All underwent dipyridam...

Cortigiani, Lauro; Rigo, Fausto; Sciari, Rosa; Gherardi, Sonia; Bovenzi, Francesco; Picano, Eugenio

2009-01-01

147

Measurement of coronary sinus blood flow after first anterior myocardial infarction transthoracic echocardiography and its correlation with wall motion scoring lndex  

International Nuclear Information System (INIS)

The aim of this study was measurement of Coronary Sinus Blood Flow (CSBF) and Coronary Sinus Velocity time Integral (CSVTI) via transthoracic echocardiography (TTE) in patients with acute myocardial infarction (AMI) in association with left ventricular ejection fraction (LVEF), wall motion scoring index (WMSI) and in-hospital mortality. Twenty patients with anterior AMI and 20 healthy individuals as controls, were studied in 6 months period in 2005 in Madani Heart Center in Tabriz, Iran. All received same drugs for AMI treatment (e.g. fibrinolytic). CSBF, CSVTI, WMSI and tissue Doppler imaging (TDI) data were obtained via TTE and compared between the two groups. Baseline variables were similar between two groups (p>0.05). CSBF in AMI group was 287.8 +- 128 ml/min and 415 +- 127 ml/min in control group (p=0.001). CSVTI was significantly lower in AMI group than control group (11.16 +- 2.85 and 17.56 +- 2.72 mm, respectively; p = 0.003). There was significant correlation between CSBF and LVEF (r = 0.52, p= 0.01), WMSI (r -0.77, p = 0.0001) and in-hospital mortality (r=0.58 p= 0.03), also between CSVTI and LVEF (r = 0.85, p = 0.0001), WMSI (r = -0.57, p = 0.0009) and in hospital-mortality rate (r = 0.69, p = 0.02). CSBF and CSVTI had good correlation with TDI findings: Em (peak early diastolic velocity in the myocardium) and Sm (peak systolic velocity in the myocardium). Our study demonstrated good correlation between measured CSBF and CSVTI by 2D, Doppler TTE and LVEF, WF and CSVTI by 2D, Doppler TTE and LVEF, WMSI, in-hospital mortality and also TDI findings; also we found that CSBF and CSVTI were independent predictors in AMI patients. (author)

148

Systematic review and network meta-analysis of combination and monotherapy treatments in disease-modifying antirheumatic drug-experienced patients with rheumatoid arthritis: analysis of American College of Rheumatology criteria scores 20, 50, and 70  

Directory of Open Access Journals (Sweden)

Full Text Available Michelle E Orme,1 Katherine S MacGilchrist,2 Stephen Mitchell,2 Dean Spurden,3 Alex Bird31Icera Consulting, Swindon, Wiltshire, UK; 2Systematic Review Department, Abacus International, Bicester, Oxfordshire, UK; 3Pfizer UK Limited, Tadworth, Surrey, UKBackground: Biologic disease-modifying antirheumatic drugs (bDMARDs extend the treatment choices for rheumatoid arthritis patients with suboptimal response or intolerance to conventional DMARDs. The objective of this systematic review and meta-analysis was to compare the relative efficacy of EU-licensed bDMARD combination therapy or monotherapy for patients intolerant of or contraindicated to continued methotrexate.Methods: Comprehensive, structured literature searches were conducted in Medline, Embase, and the Cochrane Library, as well as hand-searching of conference proceedings and reference lists. Phase II or III randomized controlled trials reporting American College of Rheumatology (ACR criteria scores of 20, 50, and 70 between 12 and 30 weeks' follow-up and enrolling adult patients meeting ACR classification criteria for rheumatoid arthritis previously treated with and with an inadequate response to conventional DMARDs were eligible. To estimate the relative efficacy of treatments whilst preserving the randomized comparisons within each trial, a Bayesian network meta-analysis was conducted in WinBUGS using fixed and random-effects, logit-link models fitted to the binomial ACR 20/50/70 trial data.Results: The systematic review identified 10,625 citations, and after a review of 2450 full-text papers, there were 29 and 14 eligible studies for the combination and monotherapy meta-analyses, respectively. In the combination analysis, all licensed bDMARD combinations had significantly higher odds of ACR 20/50/70 compared to DMARDs alone, except for the rituximab comparison, which did not reach significance for the ACR 70 outcome (based on the 95% credible interval. The etanercept combination was significantly better than the tumor necrosis factor-? inhibitors adalimumab and infliximab in improving ACR 20/50/70 outcomes, with no significant differences between the etanercept combination and certolizumab pegol or tocilizumab. Licensed-dose etanercept, adalimumab, and tocilizumab monotherapy were significantly better than placebo in improving ACR 20/50/70 outcomes. Sensitivity analysis indicated that including studies outside the target population could affect the results.Conclusion: Licensed bDMARDs are efficacious in patients with an inadequate response to conventional therapy, but tumor necrosis factor-? inhibitor combination therapies are not equally effective.Keywords: bDMARD, rheumatoid arthritis, etanercept, systematic review, network meta-analysis, comparative effectiveness

Orme ME

2012-12-01

149

Insulin-like growth factor II mRNA binding protein 3 (IMP3 is overexpressed in prostate cancer and correlates with higher Gleason scores  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background The oncofetal protein insulin-like growth factor II mRNA binding protein 3 (IMP3 is an important factor for cell-migration and adhesion in malignancies. Recent studies have shown a remarkable overexpression of IMP3 in different human malignant neoplasms and also revealed it as an important prognostic marker in some tumor entities. To our knowledge, IMP3 expression has not been investigated in prostate carcinomas so far. Methods Immunohistochemical stainings for IMP3 were performed on tissue microarray (TMA organized samples from 507 patients: 31 normal prostate tissues, 425 primary carcinomas and 51 prostate cancer metastases or castration-resistant prostate cancers (CRPC. IMP3 immunoreactivity was semiquantitatively scored and correlated with clinical-pathologic parameters including survival. Results IMP3 is significantly stronger expressed in prostate carcinomas compared to normal prostate tissues (p Conclusions Although IMP3 is overexpressed in a significant proportion of prostate cancer cases, which might be of importance for novel therapeutic approaches, it does not appear to possess any immediate diagnostic or prognostic value, limiting its potential as a tissue biomarker for prostate cancer. These results might be corroborated by the fact, that two independent tumor cohorts were separately reviewed.

Mortezavi Ashkan

2010-06-01

150

Keeping Score  

Science.gov (United States)

Conductor Michael Tilson Thomas has embarked on a number of intriguing and worthy projects during his career, including a series of ambitious recordings with the San Francisco Symphony and a number of well-received concerts with the late Sarah Vaughan in the 1980s. Most recently, he has teamed up with PBS (and his colleagues in the San Francisco Symphony) to create the âÂÂKeeping Score: Revolutions in Musicâ television series. Visitors to this site can explore the very fine multimedia presentations that are meant to accompany and enhance the entire educational and aesthetic experience of the television programs. Currently, there are multimedia profiles of StravinskyâÂÂs âÂÂRite of SpringâÂÂ, BeethovenâÂÂs âÂÂEroicaâ Symphony and the development of CoplandâÂÂs approach to creating an âÂÂAmericanâ sound. Each site features a brief introduction by Thomas, and then visitors are invited into the score to follow along as the piece progresses. In the top left-hand corner of the score, visitors can watch Thomas as he conducts. Overall, the experience of this website is stimulating and edifying, without being visually (or aurally) overwhelming.

151

Correlação dos escores de risco com a anatomia coronária na síndrome coronária aguda sem supra-ST / Correlation of risk scores with coronary anatomy in non-ST-elevation acute coronary syndrome  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese FUNDAMENTO:Há poucas publicações sobre a correlação entre escores de risco e anatomia coronária na síndrome coronária aguda (SCA). OBJETIVO: Correlacionar os escores de risco com a gravidade da lesão coronária na SCA sem supra-ST. MÉTODOS: Foram analisados 582 pacientes entre julho de 2004 e outubro [...] de 2006. Avaliou-se a correlação entre os escores de risco TIMI, GRACE hospitalar e em seis meses com lesão coronária > 50%, por método não paramétrico de Spearman. Modelo de regressão logística múltipla foi realizado para determinar a habilidade preditiva dos escores em discriminar quem terá ou não lesão coronária > 50%. RESULTADOS: Foram 319 (54,8%) homens e a média de idade era 59,9 (± 10,6) anos. Correlação positiva foi observada entre a pontuação dos escores de risco e lesão coronária > 50% (escore de risco TIMI r = 0,363 [p 50% foi: TIMI = 0,704 [IC95% 0,656-0,752; p Abstract in english BACKGROUND: The literature lacks studies regarding the correlation between risk scores and coronary anatomy in acute coronary syndrome (ACS) OBJECTIVE: Correlate risk scores with the severity of the coronary lesion in ACS with non-ST elevation. METHODS: A total of 582 patients were analyzed between [...] July 2004 and October 2006. The correlation between TIMI risk scores and GRACE (hospital and six months) scores was performed for patients with coronary lesion > 50%, using Spearman´s non-parametric method. Multiple regression logistics was used to determine the predictive ability of the scores to discriminate to discriminate who will have a coronary lesion > 50%. RESULTS: Most subjects were male (319 or 54.8%), mean age of 59.9 (± 10.6) years. A positive correlation was observed between risk scores and >coronary lesion > 50% (TIMI r = 0.363 [p 50% was: TIMI = 0.704 [CI95% 0.656-0.752; p

Elizabete Silva dos, Santos; Luciano de Figueiredo, Aguiar Filho; Daniela Menezes, Fonseca; Hugo José, Londero; Rogério Martins, Xavier; Marcos Paulo, Pereira; Luiz, Minuzzo; Roberta de, Souza; Ari, Timerman.

2013-06-01

152

2011 Y?l? Yönetici Atama ve Yer De?i?tirme Yönetme?i’nin ?çeri?ine ve Puanlama Ölçütlerine ?li?kin Yönetici Görü?lerinin ?ncelenmesi
Investigation of Manager Opinions on the Content and Scoring Criteria of the 2011 Manager Appointment and Rotation Regulations
 

OpenAIRE

Purpose: This study aims at determining the opinions of managersrelating to the Manager Appointment and Rotation Regulations dated2011, the scoring criteria included in the regulations and the troublesexperienced throughout the implementation process of the regulations.Method: In this research, a qualitative approach was adopted sothat the issue can be examined thoroughly. In this research, thephenomenological pattern was employed. In the research, participantswere determined by way of sampli...

Demi?r, Selc?uk Bes?ir; Pinar, Mehmet Ali

2013-01-01

153

Acetabulum protrusio and center edge angle: new MR-imaging measurement criteria - a correlative study with measurement derived from conventional radiography  

Energy Technology Data Exchange (ETDEWEB)

The goal of this study was to identify a method of measurement for acetabulum protrusio and center edge angle (CEA) using MR imaging of the pelvis that correlated with classic methods using radiographic landmarks. MR images and radiographs of the pelvis in 67 patients (132 hips) were used to identify reliable MR-imaging methods for measuring protrusio acetabulum and CEA that correlated strongly with established radiographic measurements. Protrusio acetabulum was determined using the radiographic criterion that the acetabular line projects medial to the ilioischial line by 3 mm or more in men and 6 mm or more in women. Pearson correlation factor was used to determine inter-observer variability and those methods that demonstrated the strongest correlation. The mean and standard deviation of MR-imaging and radiographic measurements for both the normal and protrusio hips were established. Several MR methods correlated strongly with radiographic measurements. The preferred method employed axial MR images at the level of the ischial spine with measurement of the distance between the medial most point of the acetabular fossa and a line perpendicular to the horizontal axis that passed through the lateral margin of the posterior inner pelvic wall. The Pearson's correlation factor between radiographic and MR measurements using this method was 0.84, and inter-observer correlation was 0.80. There were 126 hips in 63 patients (17 female and 44 male) that did not meet the radiographic criteria for protrusio acetabula. In this group of normal hips, the mean and standard deviation of radiographic measurements were 1.9 and 2.8 mm in male patients and -0.5 and 1.7 mm in female patients, and the mean and standard deviation for the preferred MR method was 1.3 and 2.5 mm in male patients and -0.8 and 1.9 mm in female patients. A total of six hips in four patients (two female and two male) met the radiographic criteria for protrusio acetabula. In this group of patients, the mean and standard deviation of radiographic measurements were -3.7 and 1 mm in male patients and -5.4 and 0.9 mm in female patients, and the mean and standard deviation for the preferred MR method was -4.1 and 0.4 mm in male patients and -6.5 and 0.3 mm in female patients. Our study also showed that the CEA was best measured using anterior to middle coronal MR images. Posterior coronal MR-imaging measurements correlated poorly with radiographic measurements. MR imaging can be used to assess acetabular morphology and measure acetabulum protrusio. (orig.)

Chen, Lina; Resnick, Donald [VASDHS-Radiology, San Diego, CA (United States); UCSD Medical Center, San Diego, CA (United States); Boonthathip, Mayura; Cardoso, Fabiano; Clopton, Paul [VASDHS-Radiology, San Diego, CA (United States)

2009-02-15

154

Histopathological Study of Chronic Hepatitis B: A Comparative Study of Ishak and METAVIR Scoring Systems  

Directory of Open Access Journals (Sweden)

Full Text Available Background: Ishak and METAVIR scoring systems are among the most commonly used histopathological systems to evaluate chronic hepatitis.Objective: To assess the level of agreement between these two scoring systems in patients with chronic hepatitis B.Methods: Liver biopsy samples taken from 92 patients with chronic hepatitis B were considered as the training set; 57 more biopsy specimens were used as the validation set. In the training set, grade of necroinflammationand stage of fibrosis for each liver biopsy specimen were determined by two expert liver pathologists using both Ishak and METAVIR systems. Inter-observer variability between the two pathologistswas evaluated. Biopsy specimens of the validation set were seen and scored by a third expert pathologist.In the training set, criteria were developed to categorize Ishak grading and staging systems separately to best fit with the METAVIR scoring system. The criteria found in the training set, was then tested in the validation set. The level of agreement between the two scoring systems was assessed by weighted kappa statistics.Results: For the training set, agreement between the two pathologists was excellent. Using our proposed criteria in the training set, there was excellent level of agreement in grading (? = 0.89 and staging (? = 0.99 between Ishak and METAVIR systems. In the validation set, the criteria led to substantial correlation(? = 0.61 in grading, and excellent correlation (? = 0.94 in staging between the two systems.Conclusion: Using our proposed criteria, excellent or at least substantial concordance between Ishak and METAVIR scoring systems can be achieved for the degree of both necro-inflammatory changes and fibrosis.

M. Sotoudeh

2010-10-01

155

The examination of the relationship between YGS scores and music field scores in music teaching programme with special talent examination  

Directory of Open Access Journals (Sweden)

Full Text Available Every year, with special aptitude exams students are taken to undergraduate programs as a music teacher in Turkey .Although applications for these exam show differences according to the difficulty level of the questions and evaluations criterias, all the areas that would be measured show similarities to each other. The areas showing the similarity are classified as Musical hearing-reading-writing fields (M?OY , musical playing area and musical singing area. Special Ability Test score (ÖYSP Transition to Higher Education Exam scores, as well as forming the points (YGS-P and the weighted scores of Secondary Education (AOBP takes place mainly among the scores of the candidates. It is used according to the circumstances of different coefficients Placement Scores (YP in the calculation. The types of score that form YGS-P and ÖYS, which mainly affect the placemet of the students to the university, the relationship between the musical areas in ÖYSP and all correlations of the areas to each other have been seen as a basical problem of this study.761 candidates who auditioned for Music Education Program in the years 2010-2011 and 2011-2012 academic Inonu University Faculty of Education constitutes the study group . As a result of the analysis made, between the M?OY scores and YGS-P there is a meaningful relationship in positive direction and low level (r =. 08, p <. 05 In adddition, There are positive correlation and low level (r=.32, p<.01; between the musical play and M?OY area points, playing field between the musical scores of M?OY there are positive direction, the low level (r = .21, p <.05 relationship, and it has been found that there is meaningful relationship between musical play area and the Musical direction at a high level. (r=.79, p<.01

Turan Sa?er

2013-03-01

156

Diagnostic value of a breast MRI score for the prediction of malignancy of breast lesions detected solely with MRI  

International Nuclear Information System (INIS)

Purpose: to determine whether lesion scoring allows valid BI-RADS registered classification and prediction of malignancy of breast lesions detectable solely with MRI. Materials and methods: retrospective analysis of 86 patients who underwent MRI-guided localization and excisional biopsy of 100 breast lesions detectable only with MRI. Breast MRI was performed at 1.5 Tesla by means of a T1w dynamic GE sequence. The positive predictive value (PPV) for malignancy was calculated for each score criterion separately, for the total score, and for corresponding BI-RADS registered classes. The PPV was correlated with histology. Results: 31% (31/100) of breast lesions detectable only with MRI were malignant. Of the single score criteria only the lesion morphology criterion was significantly correlated with malignancy. The malignancy rate according to the breast MRI score was 0% for score 3, 18.2% for score 4, 32.1% for score 5 and each 50% for lesions of score 6 and 7. After translation into BI-RADS registered the malignancy rates were 0% for BI-RADS registered 3, 24.6% for BI-RADS registered 4 and 48.5% for BI-RADS registered 5 lesions. The thus defined BI-RADS registered classes were significantly correlated with malignancy. (orig.)

157

Correlations between FDG PET glucose uptake-MRI gray matter volume scores and apolipoprotein E ?4 gene dose in cognitively normal adults: a cross-validation study using voxel-based multi-modal partial least squares  

OpenAIRE

We previously introduced a voxel-based, multi-modal application of the partial least square algorithm (MMPLS) to characterize the linkage between patterns in a person’s complementary complex datasets without the need to correct for multiple regional comparisons. Here we used it to demonstrate a strong correlation between MMPLS scores to characterize the linkage between the covarying patterns of fluorodeoxyglucose positron emission tomography (FDG PET) measurements of regional glucose metabo...

Chen, Kewei; Ayutyanont, Napatkamon; Langbaum, Jessica B. S.; Fleisher, Adam S.; Reschke, Cole; Lee, Wendy; Liu, Xiaofen; Alexander, Gene E.; Bandy, Dan; Caselli, Richard J.; Reiman, Eric M.

2012-01-01

158

Correlations between FDG PET glucose uptake-MRI gray matter volume scores and apolipoprotein E ?4 gene dose in cognitively normal adults: a cross-validation study using voxel-based multi-modal partial least squares  

Science.gov (United States)

We previously introduced a voxel-based, multi-modal application of the partial least square algorithm (MMPLS) to characterize the linkage between patterns in a person’s complementary complex datasets without the need to correct for multiple regional comparisons. Here we used it to demonstrate a strong correlation between MMPLS scores to characterize the linkage between the covarying patterns of fluorodeoxyglucose positron emission tomography (FDG PET) measurements of regional glucose metabolism and magnetic resonance imaging (MRI) measurements of regional gray matter associated with apolipoprotein E (APOE) ?4 gene dose (i.e., three levels of genetic risk for late-onset Alzheimer’s disease (AD)) in cognitively normal, late-middle-aged persons. Coregistered and spatially normalized FDG PET and MRI images from 70% of the subjects (27 ?4 homozygotes, 36 ?4 heterozygotes and 67 ?4 non-carriers) were used in a hypothesis-generating MMPLS analysis to characterize the covarying pattern of regional gray matter volume and cerebral glucose metabolism most strongly correlated with APOE-?4 gene dose. Coregistered and spatially normalized FDG PET and MRI images from the remaining 30% of the subjects were used in a hypothesis-testing MMPLS analysis to generate FDG PET-MRI gray matter MMPLS scores blind to their APOE genotype and characterize their relationship to APOE-?4 gene dose. The hypothesis-generating analysis revealed covarying regional gray matter volume and cerebral glucose metabolism patterns that resembled those in traditional univariate analyses of AD and APOE-?4 gene dose and PET-MRI scores that were strongly correlated with APOE-?4 gene dose (p<1×10?16). The hypothesis-testing analysis results showed strong correlations between FDG PET-MRI gray matter scores and APOE-?4 gene dose (p=8.7×10?4). Our findings support the possibility of using the MMPLS to analyze complementary datasets from the same person in the presymptomatic detection and tracking of AD. PMID:22348880

Chen, Kewei; Ayutyanont, Napatkamon; Langbaum, Jessica B.S.; Fleisher, Adam S.; Reschke, Cole; Lee, Wendy; Liu, Xiaofen; Alexander, Gene E; Bandy, Dan; Caselli, Richard J.; Reiman, Eric M.

2012-01-01

159

Change in CD3 positive T-cell expression in psoriatic arthritis synovium correlates with change in DAS28 and magnetic resonance imaging synovitis scores following initiation of biologic therapy - a single centre, open-label study  

LENUS (Irish Health Repository)

Abstract Introduction With the development of increasing numbers of potential therapeutic agents in inflammatory disease comes the need for effective biomarkers to help screen for drug efficacy and optimal dosing regimens early in the clinical trial process. This need has been recognized by the Outcome Measures in Rheumatology Clinical Trials (OMERACT) group, which has established guidelines for biomarker validation. To seek a candidate synovial biomarker of treatment response in psoriatic arthritis (PsA), we determined whether changes in immunohistochemical markers of synovial inflammation correlate with changes in disease activity scores assessing 28 joints (?DAS28) or magnetic resonance imaging synovitis scores (?MRI) in patients with PsA treated with a biologic agent. Methods Twenty-five consecutive patients with PsA underwent arthroscopic synovial biopsies and MRI scans of an inflamed knee joint at baseline and 12 weeks after starting treatment with either anakinra (first 10 patients) or etanercept (subsequent 15 patients) in two sequential studies of identical design. DAS28 scores were measured at both time points. Immunohistochemical staining for CD3, CD68 and Factor VIII (FVIII) was performed on synovial samples and scored by digital image analysis (DIA). MRI scans performed at baseline and at 12 weeks were scored for synovitis semi-quantitatively. The ?DAS28 of the European League Against Rheumatism good response definition (>1.2) was chosen to divide patients into responder and non-responder groups. Differences between groups (Mann Whitney U test) and correlations between ?DAS28 with change in immunohistochemical and MRI synovitis scores (Spearman\\'s rho test) were calculated. Results Paired synovial samples and MRI scans were available for 21 patients (8 anakinra, 13 etanercept) and 23 patients (8 anakinra, 15 etanercept) respectively. Change in CD3 (?CD3) and CD68 expression in the synovial sublining layer (?CD68sl) was significantly greater in the disease responders compared to non-responders following treatment (P = 0.005 and 0.013 respectively). ?CD3, but not ?CD68 or ?FVIII, correlated with both ?DAS28 (r = 0.49, P = 0.025) and ?MRI (r = 0.58, P = 0.009). Conclusions The correlation of ?CD3 with ?DAS28 and ?MRI following biologic treatment in this cohort contributes to the validation of ?CD3 as a synovial biomarker of disease response in PsA, and supports the further evaluation of ?CD3 for predictive properties of future clinical outcomes.

Pontifex, Eliza K

2011-01-27

160

Comparison between Oncotype DX test and standard prognostic criteria in estrogen receptor positive early-stage breast cancer  

Directory of Open Access Journals (Sweden)

Full Text Available Objective: To compare the prognosis estimated by standardprognostic criteria versus the prognosis estimated by the OncotypeDX. Methods: A retrospective study was performed on 22 patientswith positive estrogen receptor, early-stage breast cancer whohad an Oncotype DX recurrence score available. Results: Kappavalue between Oncotype DX and standard prognostic criteriawas: Adjuvant! (K = 0.091, Adjuvant! (Transbig (K = 0.182 andNational Comprehensive Cancer Network (K = 0.091. The Fisher’sexact test did not show correlation between Oncotype and standardprognostic criteria. Conclusion: Standard prognostic criteria showedno correlation with Oncotype DX.

Marcelo Roberto Pereira Freitas

2011-09-01

161

Ethics Requirement Score: new tool for evaluating ethics in publications.  

Science.gov (United States)

Objective To analyze ethical standards considered by health-related scientific journals, and to prepare the Ethics Requirement Score, a bibliometric index to be applied to scientific healthcare journals in order to evaluate criteria for ethics in scientific publication. Methods Journals related to healthcare selected by the Journal of Citation Reports™ 2010 database were considered as experimental units. Parameters related to publication ethics were analyzed for each journal. These parameters were acquired by analyzing the author's guidelines or instructions in each journal website. The parameters considered were approval by an Internal Review Board, Declaration of Helsinki or Resolution 196/96, recommendations on plagiarism, need for application of Informed Consent Forms with the volunteers, declaration of confidentiality of patients, record in the database for clinical trials (if applicable), conflict of interest disclosure, and funding sources statement. Each item was analyzed considering their presence or absence. Result The foreign journals had a significantly higher Impact Factor than the Brazilian journals, however, no significant results were observed in relation to the Ethics Requirement Score. There was no correlation between the Ethics Requirement Score and the Impact Factor. Conclusion Although the Impact Factor of foreigner journals was considerably higher than that of the Brazilian publications, the results showed that the Impact Factor has no correlation with the proposed score. This allows us to state that the ethical requirements for publication in biomedical journals are not related to the comprehensiveness or scope of the journal. PMID:25628189

Santos, Lígia Gabrielle Dos; Fonseca, Ana Carolina da Costa E; Bica, Claudia Giuliano

2014-12-01

162

Empirical Bayes Estimates of Domain Scores under Binomial and Hypergeometric Distributions for Test Scores.  

Science.gov (United States)

Two simple empirical approximate Bayes estimators are introduced for estimating domain scores under binomial and hypergeometric distributions respectively. Criteria are established regarding use of these functions over maximum likelihood estimation counterparts. (SLD)

Lin, Miao-Hsiang; Hsiung, Chao A.

1994-01-01

163

Correlation between computer-aided dynamic gadolinium-enhanced MRI assessment of inflammation and semi-quantitative synovitis and bone marrow oedema scores of the wrist in patients with rheumatoid arthritis--a cohort study  

DEFF Research Database (Denmark)

Objective. To test the correlation between assessment of inflammation using dynamic contrast-enhanced MRI (DCE-MRI) analysed by a novel computer-aided approach and semi-quantitative scores of synovitis and bone marrow oedema (BME) using the OMERACT-RA MRI Scoring (RAMRIS) system, in the wrist of patients with RA. Methods. Fifty-four RA patients had conventional and DCE-MRI of a symptomatic wrist using a low-field 0.2T extremity scanner. RAMRIS synovitis and BME of the wrist joint were done. DCE-MRI data were analysed in three ways: (i) in all images (fully automated approach), (ii) within a large extended region of interest (ROI) placed around the wrist joint (semi-automated approach) and (iii) within a small ROI placed in the area with most visual enhancement (semi-automated approach). Time spent on each procedure was noted. Spearman's rank correlation test was applied to assess the correlation between RAMRIS and the computer-generated dynamic parameters. Results. RAMRIS synovitis (range 2-9), BME (range 0-39) and the dynamic parameters reflecting the number of enhancing voxels were significantly correlated, especially when an extended ROI around the wrist was used (¿¿=¿0.74; P¿

Boesen, Mikael; Kubassova, Olga

2012-01-01

164

Checklist for Evaluating SREB-SCORE Learning Objects  

Science.gov (United States)

This checklist is based on "Evaluation Criteria for SREB-SCORE Learning Objects" and is designed to help schools and colleges determine the quality and effectiveness of learning objects. It is suggested that each learning object be rated to the extent to which it meets the criteria and the SREB-SCORE definition of a learning object. A learning…

Southern Regional Education Board (SREB), 2007

2007-01-01

165

Prognostic value of perfusion defect volume at dual energy CTA in patients with pulmonary embolism: Correlation with CTA obstruction scores, CT parameters of right ventricular dysfunction and adverse clinical outcome  

International Nuclear Information System (INIS)

Purpose: To investigate the prognostic value of perfusion defect volume (PDvol) at dual-energy-CT-angiography (DE-CTA) in patients with acute pulmonary embolism (PE) by correlating PDvol with CTA-obstruction-scores (OS), CT parameters of right-ventricular-dysfunction (RVD), and adverse-clinical-outcome. Materials and methods: DE-CTA of 60 patients (mean age: 65 ± 14.4 years) with PE were analyzed. Iodine maps were generated, and normalized PDvol – defined as volume of perfusion defects/total lung volume – was quantified. Furthermore, established prognostic parameters (Qanadli and Mastora-OS, and CT parameters of RVD) were obtained. CT parameters of RVD – namely the right ventricle/left ventricle (RV/LV) diameter ratio measured on transverse sections (RV/LVtrans), four-chamber views (RV/LV4ch), and RV/LV volume ratios (RV/LVvol) – were assessed. PDvol was correlated with OS, CT parameters of RVD and adverse clinical outcome (defined as the need for intensive care treatment or death). Results: 10 of 60 patients with PE experienced adverse clinical outcome. Patients with adverse clinical outcome showed significantly higher PDvol (35 ± 11% vs. 23 ± 10%, p = 0.002), RV/LV ratios (RV/LV4ch 1.46 ± 0.32 vs. 1.18 ± 0.26, p = 0.005; RV/LVvol 2.25 ± 1.33 vs. 1.19 ± 0.56, p = 0.002) and higher Mastora global scores (52 vs. 13, p = 0.02) compared to those without adverse clinical outcome. A weak correlation was observed between PDvol and the Mastora global score (r = 0.5; p = 0.0003), as well as between PDvol and RV/LV4Ch (r = 0.432, p = 0.0006). No correlation was found between PDvol and the Qanadli score or the remainder of the RVD-CT parameters. Conclusion: The extent of perfusion defects as assessed by DE-CTA correlates with adverse clinical outcome in patients with PE. Therefore, volumetric quantification of perfusion defects at DE-CTA allows the identification of low-risk patients who do not require intensified monitoring and treatment.

166

Prognostic value of perfusion defect volume at dual energy CTA in patients with pulmonary embolism: Correlation with CTA obstruction scores, CT parameters of right ventricular dysfunction and adverse clinical outcome  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To investigate the prognostic value of perfusion defect volume (PDvol) at dual-energy-CT-angiography (DE-CTA) in patients with acute pulmonary embolism (PE) by correlating PDvol with CTA-obstruction-scores (OS), CT parameters of right-ventricular-dysfunction (RVD), and adverse-clinical-outcome. Materials and methods: DE-CTA of 60 patients (mean age: 65 {+-} 14.4 years) with PE were analyzed. Iodine maps were generated, and normalized PDvol - defined as volume of perfusion defects/total lung volume - was quantified. Furthermore, established prognostic parameters (Qanadli and Mastora-OS, and CT parameters of RVD) were obtained. CT parameters of RVD - namely the right ventricle/left ventricle (RV/LV) diameter ratio measured on transverse sections (RV/LVtrans), four-chamber views (RV/LV4ch), and RV/LV volume ratios (RV/LVvol) - were assessed. PDvol was correlated with OS, CT parameters of RVD and adverse clinical outcome (defined as the need for intensive care treatment or death). Results: 10 of 60 patients with PE experienced adverse clinical outcome. Patients with adverse clinical outcome showed significantly higher PDvol (35 {+-} 11% vs. 23 {+-} 10%, p = 0.002), RV/LV ratios (RV/LV4ch 1.46 {+-} 0.32 vs. 1.18 {+-} 0.26, p = 0.005; RV/LVvol 2.25 {+-} 1.33 vs. 1.19 {+-} 0.56, p = 0.002) and higher Mastora global scores (52 vs. 13, p = 0.02) compared to those without adverse clinical outcome. A weak correlation was observed between PDvol and the Mastora global score (r = 0.5; p = 0.0003), as well as between PDvol and RV/LV4Ch (r = 0.432, p = 0.0006). No correlation was found between PDvol and the Qanadli score or the remainder of the RVD-CT parameters. Conclusion: The extent of perfusion defects as assessed by DE-CTA correlates with adverse clinical outcome in patients with PE. Therefore, volumetric quantification of perfusion defects at DE-CTA allows the identification of low-risk patients who do not require intensified monitoring and treatment.

Apfaltrer, Paul, E-mail: paul.apfaltrer@medma.uni-heidelberg.de [Department of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim - Heidelberg University, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim (Germany); Bachmann, Valentin, E-mail: valentin.bachmann@googl.com [Department of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim - Heidelberg University, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim (Germany); Meyer, Mathias, E-mail: mr.meyer.mathias@gmail.com [Department of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim - Heidelberg University, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim (Germany); Henzler, Thomas, E-mail: Thomas.Henzler@umm.de [Department of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim - Heidelberg University, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim (Germany); Barraza, John M., E-mail: barraza@musc.edu [Department of Radiology and Radiological Science, Medical University of South Carolina, PO Box 250322, 169 Ashley Avenue, Charleston, SC 29425 (United States); Gruettner, Joachim, E-mail: joachim.gruettner@umm.de [1st Department of Medicine, University Medical Center Mannheim, Medical Faculty Mannheim - Heidelberg University, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim (Germany); Walter, Thomas, E-mail: Thomas.Walter2@umm.de [1st Department of Medicine, University Medical Center Mannheim, Medical Faculty Mannheim - Heidelberg University, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim (Germany); Schoepf, U. Joseph, E-mail: schoepf@musc.edu [Department of Radiology and Radiological Science, Medical University of South Carolina, PO Box 250322, 169 Ashley Avenue, Charleston, SC 29425 (United States); and others

2012-11-15

167

Burning mouth syndrome as a trigeminal small fibre neuropathy: Increased heat and capsaicin receptor TRPV1 in nerve fibres correlates with pain score.  

OpenAIRE

Burning mouth syndrome (BMS) is often an idiopathic chronic and intractable pain condition, affecting 1.5-5.5% of middle-aged and elderly women. We have studied the heat and capsaicin receptor TRPV1, and its regulator nerve growth factor (NGF), in BMS. Patients with BMS (n=10) and controls (n=10) were assessed for baseline and post-topical capsaicin pain scores, and their tongue biopsies immunostained for TRPV1, NGF, and structural nerve markers neurofilament and peripherin. Nerve fibres pene...

Yilmaz, Z.; Renton, T.; Yiangou, Y.; Zakrzewska, J.; Chessell, Ip; Bountra, C.; Anand, P.

2007-01-01

168

Assessment of lung disease in children with cystic fibrosis using hyperpolarized 3-Helium MRI: comparison with Shwachman score, Chrispin-Norman score and spirometry  

Energy Technology Data Exchange (ETDEWEB)

This study assesses the feasibility of hyperpolarized 3-Helium MRI in children with cystic fibrosis (CF) and correlates the findings with standard clinical parameters based on chest radiograph (CXR) and pulmonary function tests (PFT). An uncontrolled, observational study in eighteen children with cystic fibrosis aged 5 - 17 years (median 12.1 years), with different severity of disease was carried out. All subjects underwent routine clinical assessment including PFT and standard auxology; CXR was obtained and Shwachman and Chrispin-Norman scores calculated. Hyperpolarized 3-He magnetic resonance imaging (MRI) was carried out using a spin-exchange polarizer and a whole body 1.5 T scanner. Ventilation distribution images were obtained during a 21-second breath-hold and scored according to previously defined criteria. Spearman's non-parametric correlations test was performed to assess for statistical significance at the p<0.05 level. The children tolerated the procedure well. No desaturation events were observed during 3-He MRI. A significant, albeit moderate, correlation was found between MRI score and FEV1% predicted (r=-0.41; p=0.047) and FVC% predicted (r=-0.42; p=0.04), while there were trends of correlations between Shwachman score and MRI score (r=-0.38; p=0.06) and Shwachman score and FEV1% predicted (r=0.39; p=0.055). The feasibility of hyperpolarized 3-He MRI in children with CF was demonstrated. MRI appears to be able to demonstrate functional lung changes, although correlations with routine clinical tests are only moderate to poor. This non-ionising radiation technique could be useful for monitoring lung disease and assessing therapy in this patient population. (orig.)

Beek, Edwin J.R. van [University of Sheffield, Unit of Academic Radiology, Sheffield (United Kingdom); University of Iowa, Department of Radiology, Carver College of Medicine, Iowa City (United States); University of Iowa, Department of Radiology, Iowa City, IA (United States); Hill, Catherine; Woodhouse, Neil; Fichele, Stanislao; Fleming, Sally; Wild, Jim M. [University of Sheffield, Unit of Academic Radiology, Sheffield (United Kingdom); Howe, Bridget; Bott, Sandra; Taylor, Christopher J. [University of Sheffield, Academic Unit of Child Health, Sheffield (United Kingdom)

2007-04-15

169

Electrocardiographic diagnosis of left ventricular hypertrophy in aortic valve disease: evaluation of ECG criteria by cardiovascular magnetic resonance  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Left ventricular hypertrophy (LVH is a hallmark of chronic pressure or volume overload of the left ventricle and is associated with risk of cardiovascular morbidity and mortality. The purpose was to evaluate different electrocardiographic criteria for LVH as determined by cardiovascular magnetic resonance (CMR. Additionally, the effects of concentric and eccentric LVH on depolarization and repolarization were assessed. Methods 120 patients with aortic valve disease and 30 healthy volunteers were analysed. As ECG criteria for LVH, we assessed the Sokolow-Lyon voltage/product, Gubner-Ungerleider voltage, Cornell voltage/product, Perugia-score and Romhilt-Estes score. Results All ECG criteria demonstrated a significant correlation with LV mass and chamber size. The highest predictive values were achieved by the Romhilt-Estes score 4 points with a sensitivity of 86% and specificity of 81%. There was no difference in all ECG criteria between concentric and eccentric LVH. However, the intrinsicoid deflection (V6 37 ± 1.0 ms vs. 43 ± 1.6 ms, p Conclusion By calibration with CMR, a wide range of predictive values was found for the various ECG criteria for LVH with the most favourable results for the Romhilt-Estes score. As electrocardiographic correlate for concentric LVH as compared with eccentric LVH, a shorter intrinsicoid deflection and a significant ST-segment and T-wave depression in the anterolateral leads was noted.

Feuerbach Stefan

2009-06-01

170

Rape Myth Acceptance, Hypermasculinity, and SAT Scores as Correlates of Moral Development: Understanding Sexually Aggressive Attitudes in First-Year College Men  

Science.gov (United States)

Male perpetrated sexual aggression has long been recognized as a serious problem on college campuses. The purpose of this multiple regression correlation study was to assess the relationship between levels of moral development (measured by the Defining Issues Test) and the degree to which first-year college men (N = 161) ascribed to rape…

Tatum, Jerry L.; Foubert, John D.

2009-01-01

171

Reliability, validity, and cut scores of the south oaks gambling screen (SOGS) for Chinese.  

Science.gov (United States)

We examined the reliability, validity, and classification accuracy of the South Oaks Gambling Screen (SOGS) when adopted for use in Chinese. The DSM-IV criteria for pathological gambling served as the standard against which the classification accuracy of the SOGS was tested. A total of 283 Chinese adults in the community and 94 Chinese treatment-seeking gamblers were recruited. The internal reliability of the SOGS was satisfactory for the general sample and acceptable for the gambling sample. The SOGS was correlated with the DSM-IV criteria items as well as psychosocial and gambling-related problems. Relative to the DSM-IV criteria, the SOGS tended to overestimate the number of pathological gamblers in both samples. In general, we were relatively confident that individuals were not pathological gamblers if the SOGS scores were between 0 and 4 and were pathological gamblers if the SOGS were between 11 and 20. There was about 50-50 chance of being pathological gamblers if the SOGS scores were between 8 and 10. However, the probability of individuals being pathological gamblers was about 0.30 if the SOGS scores were between 5 and 7. We proposed a SOGS cut score of 8 to screen for probable pathological gambling in Chinese societies. PMID:19680794

Tang, Catherine So-kum; Wu, Anise M S; Tang, Joe Y C; Yan, Elsie C W

2010-03-01

172

Adrenoleucodistrofia ligada ao X: correlação entre o escore de Loes e parâmetros do tensor de difusão / X-linked adrenoleukodystrophy: correlation between Loes score and diffusion tensor imaging parameters  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese Objetivo: Avaliar a correlação dos parâmetros do tensor de difusão com o escore de Loes e se os parâmetros do tensor de difusão poderiam indicar alterações estruturais precoces. Materiais e Métodos: As medidas do tensor de difusão foram obtidas em 30 exames de 14 pacientes com adrenoleucodistrofi [...] a ligada ao X e foram correlacionadas com o escore de Loes. Um grupo controle de 28 pacientes masculinos foi avaliado para estabelecer medidas do tensor de difusão pareadas por idade. Análises estatísticas intra e interobservador foram feitas. Resultados: As medidas do tensor de difusão apresentam forte correlação com o escore de Loes segundo o coeficiente de Pearson (r), com valores de –0,86, 0,89, 0,89 e 0,84 para a fração de anisotropia e difusibilidades média, radial e axial (p Abstract in english Objective: The present study was aimed at evaluating the correlation between diffusion tensor imaging parameters and Loes score as well as whether those parameters could indicate early structural alterations. Materials and Methods: Diffusion tensor imaging measurements were obtained in 30 studies [...] of 14 patients with X-linked adrenoleukodystrophy and were correlated with Loes scores. A control group including 28 male patients was created to establish agematched diffusion tensor imaging measurements. Inter- and intraobserver statistical analyses were undertaken. Results: Diffusion tensor imaging measurements presented strong Pearson correlation coefficients (r) of –0.86, 0.89, 0.89 and 0.84 for fractional anisotropy and mean, radial and axial diffusivities (p

Sergio Eiji, Ono; Arnolfo de, Carvalho Neto; Emerson Leandro, Gasparetto; Luiz Otávio de Mattos, Coelho; Dante Luiz, Escuissato; Carmem Maria Sales, Bonfim; Lisandro Lima, Ribeiro.

2014-12-01

173

A Study of Relationships between the CI Scores (E-C) of High-score & Low-score Groups and Their Language Learning Strategies  

OpenAIRE

This paper investigates the relationships between language learning strategies and consecutive interpretation (CI) scores (E-C) of 120 English major students in China through a quantitative study. The analysis shows that there exist significant differences of using meta-cognitive strategy and cognitive strategy between high-score group and low-score group, sub-CI scores are positively correlated with the two strategies, and meta-cognitive strategy can positively predict the total scores. This...

Jianjun Liu

2011-01-01

174

Correlation of myocardial perfusion single photon emission computed tomography with coronary artery calcium score in coronary artery disease- An Indian perspective  

International Nuclear Information System (INIS)

Full text: Objectives: The consequences of atherosclerosis can be detected by coronary artery calcium score (CACS) and stress induced myocardial ischemia on myocardial perfusion single photon emission computed tomography (MPS). We assessed the relationship between stress induced myocardial ischemia on (MPS) and magnitude of CACS by 64 slice computed tomography (CT) in patients undergoing both tests. Methods: Our study included 59 patients with no earlier history of coronary artery disease (CAD) of both sexes (males-47, females-12) in age group of 34-69 years. Our patients were referred by cardiologists after they underwent CACS. Of these 37 patients (63%) presented with symptoms which included chest pain (non-anginal, anginal, atypical) presence or absence of shortness of breath, and rest (37%) were asymptomatic. For each patient coronary risk factors were noted. All these patients underwent CACS and rest and stress MPS one-day protocol with Tc99m sestamibi within 7 days. According to CACS and symptoms, patients were divided into four groups, group A - asymptomatic 100 n=13, group D - symptomatic >100 (n=11). The incidence of inducible ischemia in MPS was compared to the magnitude of CACS abnormality. Results: There were 21 patients (36%) with ischemic MPS. According to groups, group A - 11%(n=1), groupB- 38%(n=10), groupC- 30%(n=4) and group D- 54%(n=6) had ischemic MPS. From the above we observed thathemic MPS. From the above we observed that incidence of ischemic MPS is more with increasing CACS. And also it is noted that it is more frequent in patients who presented with symptoms irrespective of CACS who are at short-term risk. In negative MPS, CACS may be useful in long term risk stratification in finding out subclinical atherosclerosis. Conclusion: The general perception is that the CACS is a good tool for long-term risk stratification but it may be applicable to those patients with no significant risk factors. When there are risk factors MPS is a better indicator for risk stratification for CAD irrespective of CACS. Further studies incorporating prognostic follow- up are required. (author)

175

Dual-energy X-ray absorptiometry diagnostic discordance between Z-scores and T-scores in young adults.  

LENUS (Irish Health Repository)

Diagnostic criteria for postmenopausal osteoporosis using central dual-energy X-ray absorptiometry (DXA) T-scores have been widely accepted. The validity of these criteria for other populations, including premenopausal women and young men, has not been established. The International Society for Clinical Densitometry (ISCD) recommends using DXA Z-scores, not T-scores, for diagnosis in premenopausal women and men aged 20-49 yr, though studies supporting this position have not been published. We examined diagnostic agreement between DXA-generated T-scores and Z-scores in a cohort of men and women aged 20-49 yr, using 1994 World Health Organization and 2005 ISCD DXA criteria. Four thousand two hundred and seventy-five unique subjects were available for analysis. The agreement between DXA T-scores and Z-scores was moderate (Cohen\\'s kappa: 0.53-0.75). The use of Z-scores resulted in significantly fewer (McNemar\\'s p<0.001) subjects diagnosed with "osteopenia," "low bone mass for age," or "osteoporosis." Thirty-nine percent of Hologic (Hologic, Inc., Bedford, MA) subjects and 30% of Lunar (GE Lunar, GE Madison, WI) subjects diagnosed with "osteoporosis" by T-score were reclassified as either "normal" or "osteopenia" when their Z-score was used. Substitution of DXA Z-scores for T-scores results in significant diagnostic disagreement and significantly fewer persons being diagnosed with low bone mineral density.

Carey, John J

2009-01-01

176

2011 Y?l? Yönetici Atama ve Yer De?i?tirme Yönetme?i’nin ?çeri?ine ve Puanlama Ölçütlerine ?li?kin Yönetici Görü?lerinin ?ncelenmesi Investigation of Manager Opinions on the Content and Scoring Criteria of the 2011 Manager Appointment and Rotation Regulations  

Directory of Open Access Journals (Sweden)

Full Text Available Purpose: This study aims at determining the opinions of managersrelating to the Manager Appointment and Rotation Regulations dated2011, the scoring criteria included in the regulations and the troublesexperienced throughout the implementation process of the regulations.Method: In this research, a qualitative approach was adopted sothat the issue can be examined thoroughly. In this research, thephenomenological pattern was employed. In the research, participantswere determined by way of sampling for maximum diversity-one of theintentional sampling methods. The study group of the research consistsof 8 managers holding Office in the city X (pseudonym. Terms of Officeof the participants varies between 25 and 8 years. Semi-structuredinterview form was used as data collection tools in the research. All theinterviews were recorded on a tape recorder throughout the research. A240-minute interview was had within the scope of the research; the taperecording was computerized through the Microsoft Word processingprogram as raw data without being subjected to any screening.Line by line analysis described by Patton, (2002 was employed todescribe opinions expressed clearly and directly or implied in anindirect manner by the participants on the aim of the study withoutmanipulating them. Inductive descriptive analysis, content analysis andthe constant comparison technique was used in the interpretation ofthe interview data. The descriptive analysis project is made up of fourmain stages, namely, building up the thematic framework, processingdata according to the thematic framework, identifying the findings andinterpreting the findings.During content analysis, on the other hand, the data was dividedinto parts first and then these parts were investigated and compared.Later, meaningful concepts were built from these parts and the codesevoking the same concepts were grouped under a joint category. In thefinal stage, content integrity was derived from the themes stemmingfrom the data and interpreted.While developing an interview form, a conceptual frameworkrelating to the subject matter was formed by investigating the relatedbody of literature for the purposes of increasing credibility/ internalvalidity of the research. Each stage of the research process wasprovided to the reader in a detailed manner so that thetransferability/external validity of the research could be insured. Theresearcher has watched over to write his research report in detail andtried to present detailed descriptions in the findings part.All the data obtained throughout the research process wasevaluated and separately coded by the researcher and an instructor,who has a command of qualitative research methods and a consensuswas reached on the codings in general terms. Results: As a result of analysis of the data, three main subjects, namely, 1. Evaluations relating to the appointment and change of Office of managers, 2. Evaluations relating to the content of the Manager Appointment and Change of Office Regulations and to the scoring principles, 3. Evaluations relating to compulsory rotation appeared.As a result of the story, it was concluded that the belief that the awards (certificates of appreciation and high achievement granted by the Ministry of National Education central organization and provincial organizations and by the related civilian authority are not offered based on merits, justice and qualification and in line with objective criteria dominated the participants and based on this idea, they had the idea that scoring of these awards in the manager appointment process may lead to unfair competition and injustice.It was found out in the study that the participants objected not to the scoring of the awards in the appointment of manager; just to the contrary, they argued against the scoring of these awards in the manager appointment process based on the idea that the awards granted were not given according to objective criteria.It was observed that the participants believing that there is a relationship between the term of Office and experience an

Selçuk Be?ir DEM?R

2013-07-01

177

Super Bowl Scores  

Science.gov (United States)

This Illumination activity focuses on analyzing the scores for football games. Students study combinations of numbers to produce possible scores for football games. The lesson includes a student worksheet and extension questions.

2009-01-01

178

Prediction of bronchopulmonary dysplasia by chest radiographic scoring system at seven days of age  

International Nuclear Information System (INIS)

Recent trials of preventive dexamethasone therapy in preterm neonates at high risk of developing bronchopulmonary dysplasia (BPD) have required the objective criteria for prediction of BPD in the early neonatal period. The purpose of this study is to determine whether a chest radiographic scoring system at 7 days of age can be used to predict BPD. Chest radiographs taken at 7 days and 28 days of age in 59 preterm neonates(gestational age of less than 33 weeks) were scored prospectively according to the consensus of two radiologists. The 7-day radiographs were scored according to a system derived from Yuksel's method:endotracheal tube insertion, degree of lung inflation, lung opacification, interstitial changes and cardiomegaly were measured. The radiographs taken at 28 days were scored according to a modification of Toce's method. The BPD group was defined as consisting of patients who needed oxygen therapy for more than 28 days and showed abnormality on chest radiographs. Scores were analysed to determine whether there were any statistical differences between the BPD and non-BPD groups, whether there was a significant correlation between scores at 7 days and 28 days, and whether there was any relationship between scores at 7 days of age and the development of BPD. We tried to determine which factors, as indicated by the scores at 7 days, significantly contributed to the development of BPD. The mean scores at 7 days of age in the BPD group (n=18) were 4.3±1.5 (2-7), the BPD group (n=18) were 4.3±1.5 (2-7), and those in the non-BPD group (n=41) were 2.2±1.2 (0-4). The differences were statistically significant (p<.0001). Significant correlation was found between scores at 7 days and at 28 days of age(r:0.57, p<.0001). Analysis showed that endotracheal tube insertion, cardiomegaly, and degree of interstitial change, as seen on radiographs at 7 days, were factors which significantly contributed to the development of BPD (p<0.05 each). All neonates with a score of 5 or more developed BPD (7/7), while those with a score of less than 2 did not (0/11). The chest radiographic scoring system used at 7 days of age can be helpful in predicting the development of BPD. We believe that this system can be used to indicate the need for early preventive steroid therapy

179

Analysis of Project Success Criteria in the Nigerian Construction Industry  

Directory of Open Access Journals (Sweden)

Full Text Available This paper examined the relative importance of the project success criteria in the Nigerian construction industry. It also determined the correlation among the project success criteria. Based on the literatures reviewed, the study proposed a framework for measuring project success in the construction industry. The respondents for the study were the government, private clients, consultants and contractors. Three hundred copies of questionnaires were distributed to capture data on the subject, but only 86 were returned and used for the study. The paper captured respondents that are resident in Lagos state, Nigeria and chosen by convenience from selected organizations used for the study. The data were analysed with SPSS 16 through the use of frequencies, mean scores, factor analysis and correlation. Factor analysis was employed because the mean scores showed that all the project success criteria were at least important. Nine principal components were finally merged into 4 through the factor analysis using the Varimax rotation with Keiser normalization. The study found out that all the project success criteria were important but their level of importance differs according to the factor analysis carried out. Therefore, it was concluded that there are four major components of construction project success in Nigeria- user-related factors, professionals’ factors, organisational factors and other minor factors. The minor factors were found to be related to both organizations and projects but were not highly rated by respondents for determining construction project success. The study also concludes that project success criteria goes beyond meeting cost, time and quality target, it includes users’ satisfaction, professionals’ fulfilment and achievement of organizational goals. The recommendation of the study was that for construction projects to be successful, attention must be paid to users’ related factors, professionals’ factors and organizations’ factors.

Oluwaseun Sunday Dosumu

2013-02-01

180

Algorithmic scoring models  

Directory of Open Access Journals (Sweden)

Full Text Available This article is devoted to the analysis of different credit scoring modeling techniques which can be used for the large datasets processing. Credit scoring is a basis of the banking system. There are lots if information gathered in the banks’ databases which should be used in the scoring. This article describes the basic methods and technologies of scoring models development for the risk management of the banking system.

K. Nurlybayeva

2013-01-01

181

Algorithmic scoring models  

OpenAIRE

This article is devoted to the analysis of different credit scoring modeling techniques which can be used for the large datasets processing. Credit scoring is a basis of the banking system. There are lots if information gathered in the banks’ databases which should be used in the scoring. This article describes the basic methods and technologies of scoring models development for the risk management of the banking system.

Nurlybayeva, K.; Balakayeva, G.

2013-01-01

182

Image quality criteria in cardiology  

International Nuclear Information System (INIS)

Image quality evaluation plays a key role in the process of optimisation in radiological procedures. Image quality criteria for cardiac cine-angiography were recently agreed as part of a European Research Project, and a scoring system based on these criteria has been developed to allow an 'objective' measurement of the quality of cardiac angiograms. Two studies aimed at the evaluation of the methodology have been completed, demonstrating that the method can be applied to cardiac images and translated into a scoring system that yields reproducible data. Based on the results of these studies, quality criteria have been further reviewed by DIMOND III panel and the updated version is presented in this paper. (authors)

183

Correlation Analysis of the quality of medical quality economic and financial management using correlation coefficients based on nonparametric data  

OpenAIRE

Starting from the idea that the use of multi-criteria analysis of performance within the hospital system allows a more accurate validation of employment, compared to the current methodology and seeking correlations between scores practiced economic efficiency and technical competence for all hospitals analyzed we see that there is a correlation between these values which suggests that hospital management's performance is a delusion because subordanarea different and multiple units of the heal...

Iacob, Constanta; Constantin, Camelia

2014-01-01

184

CT densitovolumetry in children with obliterative bronchiolitis: correlation with clinical scores and pulmonary function test results / Densitovolumetria pulmonar por TC em criancas com bronquiolite obliterante: correlacao com escores clinicos e testes de funcao pulmonar  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in portuguese OBJETIVO: Determinar as correlações entre o volume de aprisionamento aéreo em relação ao volume pulmonar total (AA%) e parâmetros clínicos e funcionais em crianças com bronquiolite obliterante (BO). MÉTODOS: Técnicas de pós-processamento de imagem foram usadas em imagens de TC de 19 crianças c [...] om BO para quantificar AA% por meio de um limiar fixo de ?950 UH (AA%950) e de limiares selecionados por meio de máscaras de densidade (AA%MD). Os pacientes foram divididos em três grupos, de acordo com a gravidade de AA%. Foram examinadas as correlações entre AA% e a saturação de oxigênio (SO2) em repouso, a distância percorrida no teste de caminhada de seis minutos (DTC6), a SO2 mínima durante o teste de caminhada de seis minutos (SO2_TC6), a CVF, o VEF1, a relação VEF1/CVF e parâmetros clínicos. RESULTADOS: A DTC6 foi maior nos pacientes com maiores volumes pulmonares normais (r = 0,53). Na amostra como um todo, encontramos (antes e depois da exclusão de valores extremos, respectivamente), correlações estatisticamente significativas entre AA%950 e o escore clínico (r = 0,72; 0,80), a CVF (r = 0,24; 0,59), o VEF1 (r = ?0,58; ?0,67) e a relação VEF1/CVF (r = ?0,53; r = ?0,62), bem como entre AA%MD e o escore clínico (r = 0,58; r = 0,63), a SO2 em repouso (r = ?0,40; r = ?0,61), a SO2_TC6 (r = ?0,24; r = ?0,55), a CVF (r = ?0,44; r = ?0,80), o VEF1 (r = ?0,65; r = ?0,71) e a relação VEF1/CVF (r = ?0,41; r = ?0,52). CONCLUSÕES: Os resultados deste estudo mostram que AA% correlaciona-se significativamente com escores clínicos e testes de função pulmonar em crianças com BO. Abstract in english OBJECTIVE: To determine whether air trapping (expressed as the percentage of air trapping relative to total lung volume [AT%]) correlates with clinical and functional parameters in children with obliterative bronchiolitis (OB). METHODS: CT scans of 19 children with OB were post-processed for A [...] T% quantification with the use of a fixed threshold of ?950 HU (AT%950) and of thresholds selected with the aid of density masks (AT%DM). Patients were divided into three groups by AT% severity. We examined AT% correlations with oxygen saturation (SO2) at rest, six-minute walk distance (6MWD), minimum SO2 during the six-minute walk test (6MWT_SO2), FVC, FEV1, FEV1/FVC, and clinical parameters. RESULTS: The 6MWD was longer in the patients with larger normal lung volumes (r = 0.53). We found that AT%950 showed significant correlations (before and after the exclusion of outliers, respectively) with the clinical score (r = 0.72; 0.80), FVC (r = 0.24; 0.59), FEV1 (r = ?0.58; ?0.67), and FEV1/FVC (r = ?0.53; r = ?0.62), as did AT%DM with the clinical score (r = 0.58; r = 0.63), SO2 at rest (r = ?0.40; r = ?0.61), 6MWT_SO2 (r = ?0.24; r = ?0.55), FVC (r = ?0.44; r = ?0.80), FEV1 (r = ?0.65; r = ?0.71), and FEV1/FVC (r = ?0.41; r = ?0.52). CONCLUSIONS: Our results show that AT% correlates significantly with clinical scores and pulmonary function test results in children with OB.

Helena, Mocelin; Gilberto, Bueno; Klaus, Irion; Edson, Marchiori; Edgar, Sarria; Guilherme, Watte; Bruno, Hochhegger.

2013-12-01

185

7 CFR 4284.639 - Grant selection criteria.  

Science.gov (United States)

...following criteria: (a) A score of 0 to 10 points will...outside the community. (b) A score of 0 to 10 points will...exceed 40. (1) Experiencing trauma due to a major natural disaster...deterioration—10 points. (e) A score of 0 to 10 points will be...

2010-01-01

186

Teaching Performance Criteria to Students  

Science.gov (United States)

This is one chapter from a textbook entitled Scoring Rubrics in the Classroom: Using Performance Criteria for Assessing and Improving Student Performance. In this chapter, the authors link assessment and instruction by exploring the use of rubrics as instructional tools to involve students in their own assessment and improve student performance. Practical strategies for teaching performance criteria to students, involving students in peer and self-assessment, providing student-friendly feedback, and the instructional use of anchors are offered. The guiding question is: How can we use rubrics to improve, as well as judge, student performance?

187

SCORING SYSTEMS IN PEMPHIGUS  

OpenAIRE

Pemphigus is a dreaded disease encountered not infrequently in dermatology settings. While scoring systems in various dermatological conditions exist, objective parameters for assessing disease activity and therapeutic responses in pemphigus are not uniform and foolproof. This article presents various scoring systems in pemphigus.

Grover, Sanjiv

2011-01-01

188

7 CFR 1703.126 - Criteria for scoring grant applications.  

Science.gov (United States)

...unincorporated city, village, or borough having...inhabitants. (B) Rural Area means any area of...unincorporated city, village, or borough having...site (city, town, village, borough or rural area plus the...

2010-01-01

189

7 CFR 1703.126 - Criteria for scoring grant applications.  

Science.gov (United States)

...economic, education, or health...provided by the project include, but...electing to attend higher education institutions...provided by the project. A strong...planning, development, and support...Department of Agriculture. (2)...

2010-01-01

190

The Southampton Dupuytren's Scoring Scheme.  

Science.gov (United States)

The aim of this study was to construct and validate a simple patient-related outcome score to quantify the disability caused by Dupuytren's disease (DD), thus enabling prioritisation of treatment, to allow reliable audit of surgical outcome and to support future research. The Southampton Dupuytren's Scoring System (SDSS) was developed in a staged fashion according to the recommendations of The Derby Outcomes Conference. (1) Item generation; (2) Item reduction; (3) Internal consistency; (4) Test-re-test; (5) Field management; (6) Sensitivity to change standardised response mean; and (7) Criterion validity: ability of the SDSS to measure what it is supposed to measure. Internal consistency measured with Cronbach's alpha indicated acceptable reliability. The test-re-test correlation coefficient showed high reliability with SDSS. Field-testing showed SDSS ratings to be higher than the QuickDASH (Disability of the arm, shoulder and hand) ratings evaluated by the patients who answered both questionnaires. Standardised response mean was more sensitive for SDSS compared with QuickDASH showing sensitivity to change. Criterion validity was used to assess if the SDSS was measuring what it is supposed to measure comparing the SDSS with QuickDASH. A highly significant correlation was found between the two scoring systems. SDSS is a disease-specific patient-related outcome measure with a good internal consistency and performs better than QuickDASH in terms of test-re-test reliability and sensitivity to change. SDSS shows better field-testing attributes suggesting that it is a relatively more patient and practitioner friendly scoring system. This study proposes to the SDSS is a useful patient-related outcome measure for DD. PMID:24428161

Mohan, Arvind; Vadher, Jane; Ismail, Hiba; Warwick, David

2014-02-01

191

NISS a Valuable Tool for Trauma Scoring on Autopsy  

Directory of Open Access Journals (Sweden)

Full Text Available A retrospective autopsy-based study conducted in correlation with the relevant clinical records and the reports from investigating agencies to analyze the suitability of Injury Severity Score (ISS and New Injury Severity Score (NISS in predicting the mortality of trauma victims. Four hundred and forty six autopsy reports of the victims of road traffic accidents were thoroughly studied and the external and internal injuries were assigned AIS coding. Based on this coding ISS and NISS scoring was done. On comparing both scoring systems it was found that ISS, satisfactorily correlates to the survival period among the trauma patients of multiple wounds but NISS was a better scoring system.

B.R. Sharma

2005-01-01

192

Volleyball Scoring Systems.  

Science.gov (United States)

The widespread interest in sports in our culture provides an excellent opportunity to catch students' attention in mathematics and statistics classes. One mathematically interesting aspect of volleyball, which can be used to motivate students, is the scoring system. (MM)

Calhoun, William; Dargahi-Noubary, G. R.; Shi, Yixun

2002-01-01

193

Impartial Scoring Play Games  

CERN Document Server

In this paper we will be examining impartial scoring play games. We first give the basic definitions for what impartial scoring play games are and look at their general structure under the disjunctive sum. We will then examine the game of nim and all octal games, and define a function that can help us analyse these games. We will finish by looking at the properties this function has and give many conjectures about the behaviour this function exhibits.

Stewart, Fraser

2012-01-01

194

The Bayesian Score Statistic  

OpenAIRE

We propose a novel Bayesian test under a (noninformative) Je?reys’ prior speci?ca- tion. We check whether the ?xed scalar value of the so-called Bayesian Score Statistic (BSS) under the null hypothesis is a plausible realization from its known and standard- ized distribution under the alternative. Unlike highest posterior density regions the BSS is invariant to reparameterizations. The BSS equals the posterior expectation of the classical score statistic and it pro...

Kleibergen, F. R.; Kleijn, R. H.; Paap, R.

2000-01-01

195

Using Regression to Establish Weights for a Set of Composite Equations through a Numerical Analysis Approach: A Case of Admission Criteria to a College  

Directory of Open Access Journals (Sweden)

Full Text Available Problem statement: Mathematically little is known of college admission criteria as in school grade point average, admission test scores or rank in class and weighting of the criteria into a composite equation. Approach: This study presented a method to obtain weights on ?composite admission? equation. The method uses an iterative procedure to build a prediction equation for an optimal weighted admission composite score. The three-predictor variables, high school average, entrance exam scores and rank in class, were regressed on college Grade Point Average (GPA. The weights for the composite equation were determined through regression coefficients and numerical approach that correlate the composite score with college GPA. Results: A set of composite equations were determined with the weights on each criteria in a composite equation. Conclusion: This study detailed a substantiated algorithm and based on an optimal composite score, comes out with an original and unique structured composite score equation for admissions, which can be used by admission officers at colleges and universities.

Ramzi N. Nasser

2010-01-01

196

A Study of Relationships between the CI Scores (E-C of High-score & Low-score Groups and Their Language Learning Strategies  

Directory of Open Access Journals (Sweden)

Full Text Available This paper investigates the relationships between language learning strategies and consecutive interpretation (CI scores (E-C of 120 English major students in China through a quantitative study. The analysis shows that there exist significant differences of using meta-cognitive strategy and cognitive strategy between high-score group and low-score group, sub-CI scores are positively correlated with the two strategies, and meta-cognitive strategy can positively predict the total scores. This indicates that the use of language learning strategies does have an impact on interpreting study.

Jianjun Liu

2011-10-01

197

Introduction of a new standardized assessment score of spine morphology in osteogenesis imperfecta  

Energy Technology Data Exchange (ETDEWEB)

Purpose: Osteogenesis imperfecta (OI) is a rare hereditary disease leading to multiple bone deformities and fractures. In the absence of causal therapy, a symptomatic approach is based on treatment with bisphosphonates and physiotherapy. The clinical and radiological manifestations vary. Therefore, standardization and quantification for an objective comparison, especially during therapy, are required. In this paper, radiological changes of the spine are quantified according to their clinical relevance to define a scoring system that transfers the morphological changes into a single value representing the severity of the disease. Materials and Methods: 268 lateral spine X-rays of 95 patients with OI (median age 5.6 years) were assessed. The findings were classified based on their clinical relevance. Results: The three criteria, vertebral compression, thoracolumbar kyphosis and deformity type, were quantified in a new grading system. Based on this, a 'severity classification' (1 to 5) was defined with implications for diagnostics and treatment. A mathematical formula that takes into account the three criteria and their correlations to clinical relevance, resulting in a 'severity score', was developed. Conclusion: 'Severity classification' and 'severity score' introduce a new concept for a standardized evaluation of spine X-rays in patients with OI. For both scientific and routine purposes, it provides the user with a simple and easy-to-handle tool for assessing and comparing different stages of severity prior to and during therapy with detailed accuracy. (orig.)

Koerber, F.; Schulze Uphoff, U.; Koerber, S.; Maintz, D. [Koeln Univ. (Germany). Dept. of Radiology; Schoenau, E.; Semler, O. [Koeln Univ. (Germany). Children' s Hospital

2012-08-15

198

Introduction of a new standardized assessment score of spine morphology in osteogenesis imperfecta  

International Nuclear Information System (INIS)

Purpose: Osteogenesis imperfecta (OI) is a rare hereditary disease leading to multiple bone deformities and fractures. In the absence of causal therapy, a symptomatic approach is based on treatment with bisphosphonates and physiotherapy. The clinical and radiological manifestations vary. Therefore, standardization and quantification for an objective comparison, especially during therapy, are required. In this paper, radiological changes of the spine are quantified according to their clinical relevance to define a scoring system that transfers the morphological changes into a single value representing the severity of the disease. Materials and Methods: 268 lateral spine X-rays of 95 patients with OI (median age 5.6 years) were assessed. The findings were classified based on their clinical relevance. Results: The three criteria, vertebral compression, thoracolumbar kyphosis and deformity type, were quantified in a new grading system. Based on this, a 'severity classification' (1 to 5) was defined with implications for diagnostics and treatment. A mathematical formula that takes into account the three criteria and their correlations to clinical relevance, resulting in a 'severity score', was developed. Conclusion: 'Severity classification' and 'severity score' introduce a new concept for a standardized evaluation of spine X-rays in patients with OI. For both scientific and routine purposes, it provides the user with a simple and easy-to-handle tool for assessing and compeasy-to-handle tool for assessing and comparing different stages of severity prior to and during therapy with detailed accuracy. (orig.)

199

Comparison of Prognosis in Patients with Liver Cirrhosis and its Correlation with the Model for the End-Stage Liver Disease and Child-PughChild-Pugh Scores in Patients with Esophageal or Gastric Variceal Bleeding  

Directory of Open Access Journals (Sweden)

Full Text Available Background:Variceal bleeding is one of the most serious complications of cirrhosis. Up to now different methods are created for predicting the complications and mortality of cirrhosis. Child- Pugh score and MELD score are two methods for this use. In this study we investigated and compared survival prognosis of cirrhotic patients by the Child-Pugh or MELD score in two groups of esophageal and gastric variceal bleeding. Materials and Methods: In this cross-sectional trial, patients with upper GI bleeding were followed up for a 6 months period. The source of hemorrhage was determined by endoscopy, then patients distributed in two groups of esophageal and gastric variceal hemorrhage. Finally we investigated and compared the relationship between the variables and mortality rates in these two groups by means of the Child-Pugh and the MELD scores. The Student’s t-test and Receiver Operating Characteristic were used for statistical analysis.Results: 34 patients (12 with gastric varices, 22 with esophageal varices were investigated. No significant difference between these two groups was observed. In this study mean MELD score was 16.67±8.75 and mean Child-Pugh score was 9.37±2.54. Eight patients (5 with gastric varices and 3 with esophageal varices expired before 6 weeks and 2 patients (one four each group expired after 6 weeks. The best cut-off points are 15.5 and 10.5 for MELD and Child-Pugh scores respectively (sensitivity and specificity are 0.75 and 0.98, respectively for both scores.Conclusion:Sensitivity and specificity of both scores were the same in prediction of mortality. However, the chance ratio defined that Child-Pugh score was a better predictor of mortality than MELD score, since the chance of death will increase 2.51 and 1.62 fold per each unit increase in the Child-Pugh and the MELD scores, respectively. However, no significant difference found between Child-Pugh and MELD score between two groups of patients.

Mohammadreza Sheikhian

2013-09-01

200

Genetic effect on apgar score  

Directory of Open Access Journals (Sweden)

Full Text Available Intraclass correlation coefficients for one- and five-min Apgar scores of 604 twin pairs born at a southeastern Brazilian hospital were calculated, after adjusting these scores for gestational age and sex. The data support a genetic hypothesis only for 1-min Apgar score, probably because it is less affected by the environment than 4 min later, after the newborns have been under the care of a neonatology team. First-born twins exhibited, on average, better clinical conditions than second-born twins. The former showed a significantly lower proportion of Apgar scores under seven than second-born twins, both at 1 min (17.5% vs. 29.8% and at 5 min (7.2% vs. 11.9%. The proportion of children born with "good" Apgar scores was significantly smaller among twins than among 1,522 singletons born at the same hospital. Among the latter, 1- and 5-min Apgar scores under seven were exhibited by 9.2% and 3.4% newborns, respectively.Os coeficientes de correlação intraclasse foram calculados para os índices de Apgar 1 e 5 minutos após o nascimento de 604 pares de gêmeos em uma maternidade do sudeste brasileiro, depois que esses índices foram ajustados para idade gestacional e sexo. Os dados obtidos apoiaram a hipótese genética apenas em relação ao primeiro índice de Apgar, provavelmente porque ele é menos influenciado pelo ambiente do que 4 minutos depois, quando os recém-nascidos já estiveram sob os cuidados de uma equipe de neonatologistas. Os gêmeos nascidos em primeiro lugar apresentaram, em média, melhor estado clínico que os nascidos em segundo lugar, visto que os primeiros mostraram uma proporção de índices de Apgar inferiores a 7 significativamente menor do que os nascidos em segundo lugar, tanto um minuto (17,5% contra 29,8% quanto cinco minutos após o nascimento (7,2% contra 11,9%. A proporção de recém-nascidos com índices de Apgar que indicam bom prognóstico foi significativamente menor nos gêmeos do que em 1.522 conceptos únicos nascidos na mesma maternidade. Índices de Apgar menores do que 7, obtidos um e cinco minutos após o nascimento, foram encontrados respectivamente em 9,2% e em 3,4% dos recém-nascidos de parto único.

Carla Franchi-Pinto

1999-03-01

201

Comparative Evaluation of Urinary PCA3 and TMPRSS2: ERG Scores and Serum PHI in Predicting Prostate Cancer Aggressiveness  

Directory of Open Access Journals (Sweden)

Full Text Available It has been suggested that urinary PCA3 and TMPRSS2:ERG fusion tests and serum PHI correlate to cancer aggressiveness-related pathological criteria at prostatectomy. To evaluate and compare their ability in predicting prostate cancer aggressiveness, PHI and urinary PCA3 and TMPRSS2:ERG (T2 scores were assessed in 154 patients who underwent radical prostatectomy for biopsy-proven prostate cancer. Univariate and multivariate analyses using logistic regression and decision curve analyses were performed. All three markers were predictors of a tumor volume ?0.5 mL. Only PHI predicted Gleason score ?7. T2 score and PHI were both independent predictors of extracapsular extension (?pT3, while multifocality was only predicted by PCA3 score. Moreover, when compared to a base model (age, digital rectal examination, serum PSA, and Gleason sum at biopsy, the addition of both PCA3 score and PHI to the base model induced a significant increase (+12% when predicting tumor volume >0.5 mL. PHI and urinary PCA3 and T2 scores can be considered as complementary predictors of cancer aggressiveness at prostatectomy.

Lucile Tallon

2014-07-01

202

Comparative evaluation of urinary PCA3 and TMPRSS2: ERG scores and serum PHI in predicting prostate cancer aggressiveness.  

Science.gov (United States)

It has been suggested that urinary PCA3 and TMPRSS2:ERG fusion tests and serum PHI correlate to cancer aggressiveness-related pathological criteria at prostatectomy. To evaluate and compare their ability in predicting prostate cancer aggressiveness, PHI and urinary PCA3 and TMPRSS2:ERG (T2) scores were assessed in 154 patients who underwent radical prostatectomy for biopsy-proven prostate cancer. Univariate and multivariate analyses using logistic regression and decision curve analyses were performed. All three markers were predictors of a tumor volume?0.5 mL. Only PHI predicted Gleason score?7. T2 score and PHI were both independent predictors of extracapsular extension(?pT3), while multifocality was only predicted by PCA3 score. Moreover, when compared to a base model (age, digital rectal examination, serum PSA, and Gleason sum at biopsy), the addition of both PCA3 score and PHI to the base model induced a significant increase (+12%) when predicting tumor volume>0.5 mL. PHI and urinary PCA3 and T2 scores can be considered as complementary predictors of cancer aggressiveness at prostatectomy. PMID:25079439

Tallon, Lucile; Luangphakdy, Devillier; Ruffion, Alain; Colombel, Marc; Devonec, Marian; Champetier, Denis; Paparel, Philippe; Decaussin-Petrucci, Myriam; Perrin, Paul; Vlaeminck-Guillem, Virginie

2014-01-01

203

Description and validation of a scoring system for tomosynthesis in pulmonary cystic fibrosis  

Energy Technology Data Exchange (ETDEWEB)

To design and validate a scoring system for tomosynthesis (digital tomography) in pulmonary cystic fibrosis. A scoring system dedicated to tomosynthesis in pulmonary cystic fibrosis was designed. Three radiologists independently scored 88 pairs of radiographs and tomosynthesis examinations of the chest in 60 patients with cystic fibrosis and 7 oncology patients. Radiographs were scored according to the Brasfield scoring system and tomosynthesis examinations were scored using the new scoring system. Observer agreements for the tomosynthesis score were almost perfect for the total score with square-weighted kappa >0.90, and generally substantial to almost perfect for subscores. Correlation between the tomosynthesis score and the Brasfield score was good for the three observers (Kendall's rank correlation tau 0.68, 0.77 and 0.78). Tomosynthesis was generally scored higher as a percentage of the maximum score. Observer agreements for the total score for Brasfield score were almost perfect (square-weighted kappa 0.80, 0.81 and 0.85). The tomosynthesis scoring system seems robust and correlates well with the Brasfield score. Compared with radiography, tomosynthesis is more sensitive to cystic fibrosis changes, especially bronchiectasis and mucus plugging, and the new tomosynthesis scoring system offers the possibility of more detailed and accurate scoring of disease severity. (orig.)

Vult von Steyern, Kristina; Bjoerkman-Burtscher, Isabella M.; Bozovic, Gracijela; Wiklund, Marie; Geijer, Mats [Skaane University Hospital, Lund University, Centre for Medical Imaging and Physiology, Lund (Sweden); Hoeglund, Peter [Skaane University Hospital, Competence Centre for Clinical Research, Lund (Sweden)

2012-12-15

204

Comparison of OMERACT-RAMRIS scores and computer-aided dynamic magnetic resonance imaging findings of hand and wrist as a measure of activity in rheumatoid arthritis.  

Science.gov (United States)

The purpose of this study was to compare the value of conventional magnetic resonance imaging (MRI) finding of rheumatoid arthritis (RA) and computer-aided dynamic MRI measurements in predicting the activity of disease. The activity of the disease in 40 RA patients was evaluated by the disease activity score in 28 joints (DAS28). The conventional MRI of the wrists of all patients were scored for bone edema, synovitis and erosions, according to the criteria of RA-MRI scoring system (RAMRIS) developed by Outcome measures in rheumatology clinical trials (OMERACT) MR Imaging Group. Synovitis was also quantified by dynamic postcontrast MRI imaging using color coded maximum slope of increase maps and measurements of early enhancement rate (EER) and relative enhancement (RE). Twenty-two (55 %) patients with a score higher than 5.1 constituted the high disease activity group, 18 (45 %) patients with a score of 5.1 or less constituted moderate disease activity group. The dynamic MRI-EER score was the most significant parameter to differentiate between the groups (p = 0.001). Among OMERACT scores, only bone edema [p = 0.020 for wrist and p = 0.037 for metacarpophalangeal joints (MCP)] had a significant difference between the two groups. Dynamic MRI RE score and OMERACT scores for erosions and synovitis for both the wrist and MCP joints did not differ significantly between the two groups. Computer-aided dynamic MRI is a reliable, noninvasive method of evaluating the RA patients, which correlates with the DAS28 scores, at a higher significance than the OMERACT-RAMRIS scores. PMID:23328931

Orguc, Sebnem; Tikiz, Canan; Aslanalp, Zahide; Erbay, Pinar Dundar

2013-07-01

205

Pronuclear scoring as a predictor of embryo quality in in vitro fertilization program.  

Directory of Open Access Journals (Sweden)

Full Text Available Many strategies have been proposed for the selection of viable embryos for transfer in human assisted reproduction. These have included morphological scoring criteria for 20, 28, 44 and 68 h after insemination. The embryo selection is based on morphology, degree of fragmentation and development to the 8-cell. All have shown some correlation with implantation. However, the overall success of these methods is still limited, with over 50% of all transferred embryos failing to implant. Pronuclear zygote morphology has gained much attention recently due to its positive value in predicting implantation and pregnancy. This prospective study involved 178 conventional IVF patients only. The key aspects of pronuclear scoring and namely the presence of a cytoplasmic halo were related to day 3 of development and morphology in a retrospective study. The Z-score and the presence/absence of a halo had significant effect on the rate of development on day 3 embryo. Low Z-score result in slow development and poor morphology. The absence of a halo also resulted in slow and poor development, low morphology, increased fragmentation.

Leszek Pawelczyk

2008-04-01

206

Node-by-node correlation between MR and PET/CT in patients with uterine cervical cancer: diffusion-weighted imaging versus size-based criteria on T2WI  

International Nuclear Information System (INIS)

The purpose of the study was to perform a node-by-node comparison of an ADC-based diagnosis and various size-based criteria on T2-weighted imaging (T2WI) with regard to their correlation with PET/CT findings in patients with uterine cervical cancer. In 163 patients with 339 pelvic lymph nodes (LNs) with short-axis diameter >5 mm, the minimum apparent diffusion coefficient (ADC), mean ADC, short- and long-axis diameters, and ratio of long- to short-axis diameters (L/S ratio) were compared in PET/CT-positive and -negative LNs. On PET/CT, 118 (35%) LNs in 58 patients were positive. The mean value of minimum and mean ADCs, short- and long-axis diameters, and L/S ratio were different in PET/CT-positive (0.6436 x 10-3 mm2/s, 0.756 x 10-3 mm2/s, 10.3 mm, 13.2 mm, 1.32, respectively) and PET/CT-negative LNs (0.8893 x 10-3 mm2/s, 1.019 x 10-3 mm2/s, 7.4 mm, 11.0 mm, 1.49, respectively) (P<0.05). The Az value of the minimum ADC (0.864) was greater than those of mean ADC (0.836), short-axis diameter (0.764), long-axis diameter (0.640) and L/S ratio (0.652) (P<0.05). The sensitivity and accuracy of the minimum ADC (86%, 82%) were greater than those of the short-axis diameter (55%, 74%), long-axis diameter (73%, 58%) and L/S ratio (52%, 66%) (P<0.05). ADC showed superior correlation with PET/CT compared with conventional size-based criteria on T2WI. (orig.)ig.)

207

Satisfaction in hospitality on TripAdvisor.com: An analysis of the correlation between evaluation criteria and overall satisfaction / A satisfação na hotelaria pelo TripAdvisor: uma análise da correlação entre os critérios de avaliação e satisfação geral  

Scientific Electronic Library Online (English)

Full Text Available SciELO Portugal | Language: English Abstract in portuguese As mídias sociais alteraram a forma dos turistas buscarem e trocarem informações, determinando mudanças gerenciais para as empresas turísticas, incluindo os meios de hospedagem. Os comentários e avaliações de hóspedes têm impactado na reputação das organizações, tanto positivamente como negativament [...] e. Os sítios de conteúdo gerado pelos usuários permitem que estas informações cheguem a outros turistas, através da avaliação do serviço prestado e influenciando na decisão de novos visitantes. Desta forma, esta investigação procurou identificar a correlação entre a satisfação geral e os critérios de avaliação. Para isto, foram analisadas 660 avaliações (236 nos hotéis 03 estrelas, 125 nos hotéis 04 estrelas e 299 nos hotéis 05 estrelas) no Tripadvisor, que continham de forma independente, avaliações sobre: satisfação geral, valor (custo-benefício), localização, qualidade do sono, quartos, limpeza e serviço. Os resultados apontaram para um maior índice de correlação da satisfação geral com os critérios quarto, serviço ofertado e custo-benefício. Abstract in english Social media has changed the way tourists seek and exchange information, resulting in changes in the management of tourism businesses including hospitality facilities. Guest reviews and comments have had an impact on the reputation of organisations, both positive and negative. Websites with user-gen [...] erated content spread this information to other tourists through the evaluation of service provided and thereby influence the decision of new visitors. Accordingly, this research sought to identify the correlation between overall satisfaction and the evaluation criteria used on a website. For this, we analysed 660 reviews (236 of three-star hotels, 125 of four-star hotels and 299 of five-star hotels) on TripAdvisor, containing independent reviews including overall satisfaction, value (cost-benefit), location, sleep quality, rooms, cleanliness and service. Results showed a strong correlation of overall satisfaction with the criteria of room, service provided and cost-benefit.

Pablo Flôres, Limberger; Francisco Antonio dos, Anjos; Jéssica Vieira de Souza, Meira; Sara Joana Gadotti dos, Anjos.

2014-01-01

208

Beyond the Score: Clinical Evaluation Through Formal Psychological Assessment.  

Science.gov (United States)

Questionnaires generate numerical scores, but endorsing different sets of items could produce the same score despite reflecting qualitatively different configurations of clinical features. Formal psychological assessment (FPA) attempts to overcome this by identifying the clinical features entailed by observed response patterns. This study illustrates an application of FPA to the cleaning subscale of a questionnaire assessing obsessive-compulsive symptoms and DSM-IV-TR diagnostic criteria for obsessive-compulsive disorder. A deterministic model of the items-criteria relationships was constructed by mapping each item to each diagnostic criterion. The resulting model was tested on a large community sample (N = 4,412). Results indicate that the theoretical model has adequate fit; item error rates and probabilities for each of the criteria are examined. Clinically relevant examples of the items-criteria relationships are discussed. Possible applications of FPA to personality assessment are also discussed, including long multidimensional questionnaires and questionnaires that use subtle item content. PMID:25257993

Bottesi, Gioia; Spoto, Andrea; Freeston, Mark H; Sanavio, Ezio; Vidotto, Giulio

2014-09-25

209

7 CFR 3406.15 - Evaluation criteria for teaching proposals.  

Science.gov (United States)

...Evaluation criteria for teaching proposals. The maximum score a teaching proposal can...national electronic communication systems, publications...or research/teaching skills workshops? ...disciplines at a university, between...

2010-01-01

210

Relation of computer esthesiometry and symptom scores in diagnostics of diabetic polyneuropathy  

OpenAIRE

The purpose of our research was to define the most important diagnostic criteria in early diagnosis of distal polyneuropathy in diabetic patients. Participants included 175 patients with diabetes mellitus types 1 and 2 (male-to-female ratio 89:86, mean (±SD) age 42.02±15.27 years) with risk diabetic polyneuropathy. Research included Total Symptom Score, Neuropathy Symptom Score, Neuropathy Impairment Score, Visual Analog Score, standard somatic and neurologic status were evaluated in all pa...

Olga Darsavelidze; Elena Kantimirova; Elena Terenteva; Artem Faustov; Leonid Lipinskiy; Marina Petrova; Natalia Shnayder; Olga Kurumchina; Ilya Kiselev; Ekaterina Kozulina; Dmitriy Terskov

2010-01-01

211

Quality criteria for cardiac images: an update.  

Science.gov (United States)

The DIMOND II and III Cardiology Groups have agreed on quality criteria for cardiac images and developed a scoring system, to provide a tool to test quality of coronary angiograms, which was demonstrated to be of value in clinical practice. In the last years, digital flat panel technology has been introduced in cardiac angiographic systems and the radiological technique may have been influenced by the better performance of these new detectors. This advance in digital imaging, together with the lesson learned from previous studies, warranted the revision of the quality criteria for cardiac angiographic images as formerly defined. DIMOND criteria were reassessed to allow a simpler evaluation of angiograms. Clinical criteria were simplified and separated from technical criteria. Furthermore, the characteristics of an optimised angiographic technique have been outlined. PMID:18283064

Bernardi, G; Bar, O; Jezewski, T; Vano, E; Maccia, C; Trianni, A; Padovani, R

2008-01-01

212

Criteria for performance evaluation  

Directory of Open Access Journals (Sweden)

Full Text Available Using a cognitive task (mental calculation and a perceptual-motor task (stylized golf putting, we examined differential proficiency using the CWS index and several other quantitative measures of performance. The CWS index (Weiss and Shanteau, 2003 is a coherence criterion that looks only at internal properties of the data without incorporating an external standard. In Experiment 1, college students (n = 20 carried out 2- and 3-digit addition and multiplication problems under time pressure. In Experiment 2, experienced golfers (n = 12, also college students, putted toward a target from nine different locations. Within each experiment, we analyzed the same responses using different methods. For the arithmetic tasks, accuracy information (mean absolute deviation from the correct answer, MAD using a coherence criterion was available; for golf, accuracy information using a correspondence criterion (mean deviation from the target, also MAD was available. We ranked the performances of the participants according to each measure, then compared the orders using Spearman's rextsubscript{s}. For mental calculation, the CWS order correlated moderately (rextsubscript{s} =.46 with that of MAD. However, a different coherence criterion, degree of model fit, did not correlate with either CWS or accuracy. For putting, the ranking generated by CWS correlated .68 with that generated by MAD. Consensual answers were also available for both experiments, and the rankings they generated correlated highly with those of MAD. The coherence vs. correspondence distinction did not map well onto criteria for performance evaluation.

David J. Weiss

2009-03-01

213

Developing Scoring Algorithms  

Science.gov (United States)

We developed scoring procedures to convert screener responses to estimates of individual dietary intake for fruits and vegetables (cup equivalents), dairy (cup equivalents), added sugars (tsp), whole grains (ounce equivalents), fiber (g), and calcium (mg) using the What We Eat in America 24-hour dietary recall data from the 2003-2006 NHANES. The following equations were estimated in the NHANES 2003-2006, using SAS PROC REG.

214

score-network.org  

SCPinfonet

...org 24 February 2014 researchers members Tom Fisher Professor of Art and Design contact: Prof Tom Fisher tel: 01158488455 tom.fisher@ntu.ac.uk ...Street , Nottingham , UK biography: From a background in Design and Fine Art, Tom Fisher`s research interests are in human/ object relationships in a ... score interest / role: Tom Fisher`s interest in sustainable consumption centres on the intersection of cultural values, social relationships and materiality in everyday ...

215

Score test variable screening.  

Science.gov (United States)

Variable screening has emerged as a crucial first step in the analysis of high-throughput data, but existing procedures can be computationally cumbersome, difficult to justify theoretically, or inapplicable to certain types of analyses. Motivated by a high-dimensional censored quantile regression problem in multiple myeloma genomics, this article makes three contributions. First, we establish a score test-based screening framework, which is widely applicable, extremely computationally efficient, and relatively simple to justify. Secondly, we propose a resampling-based procedure for selecting the number of variables to retain after screening according to the principle of reproducibility. Finally, we propose a new iterative score test screening method which is closely related to sparse regression. In simulations we apply our methods to four different regression models and show that they can outperform existing procedures. We also apply score test screening to an analysis of gene expression data from multiple myeloma patients using a censored quantile regression model to identify high-risk genes. PMID:25124197

Zhao, Sihai Dave; Li, Yi

2014-12-01

216

Decisions during courtship by male and female medflies (Diptera, Tephritidae): Correlated changes in male behavior and female acceptance criteria in mass-reared flies  

International Nuclear Information System (INIS)

Analyses of more than 300 videotaped courtships of wild and mass-reared medflies from Costa Rica showed that the tendency for male and female to align themselves facing directly toward each other increased, and that the distance between them decreased as courtship proceeded. More direct alignments and shorter distances between the flies at the moment the male jumped onto the female were correlated with greater female acceptance of copulation. There were no consistent differences in durations of components of intermittent buzzing songs or male size between successful and unsuccessful courtship in either strain. Several possible cues may release different courtship responses: males of both strains tend to initiate both continuous vibration and intermittent buzzing after reduction of the distance to the female; slow creeping toward the female was associated with longer courtships that had failed to lure the female close; and females tended to turn to face more directly toward the male soon after the male began continuous vibration, and especially after he began intermittent buzzing. Females became progressively more immobile as courtship progressed, especially soon after intermittent buzzing began. There were numerous differences between strains. Mass-reared males were more likely to mount females without previous courtship than were wild males. Wild males initiated continuous wing vibration when farther from the female and when the female was looking less directly towarthe female was looking less directly toward them, but the two strains did not differ in the distances and angles at which males initiated intermittent buzzing and jumped. Wild males were more likely to creep toward the female during intermittent buzzing. Mass-reared females but not wild females were more likely to copulate when the proportion of time the male had spent in intermittent buzzing was low, and if the courtship began when the flies were nearer each other. Wild but not mass-reared females were less likely to copulate if courtship was shorter. Possible co-evolution of female responses with the five different male courtship traits that differ between mass-reared and wild flies are discussed. (author)

217

Ultrasonography-guided percutaneous radiofrequency ablation of hepatocellular carcinomas: A feasibility scoring system for planning sonography  

International Nuclear Information System (INIS)

Purpose: This study was designed to evaluate whether a feasibility scoring system for planning sonography is a reliable predictor of a safe and complete ablation in ultrasonography (US)-guided percutaneous radiofrequency ablation (RFA) of hepatocellular carcinomas (HCCs). Materials and methods: We retrospectively evaluated the therapeutic outcomes of 108 consecutive patients (M:F, 78:30; mean age, 57.4 years) with a single nodular HCC (mean diameter, 2.0 cm) treated by percutaneous RFA. All patients were assessed for the feasibility of performing an RFA at planning sonography prior to the ablation. The feasibility scoring system consisted of five categories: the safe electrode path (P); the vital organs adjacent to the RFA zone (O); tumor size (S); tumor conspicuity (C); and the heat-sink effect (H). Each category was divided into a four-point scale [1-4]. If a score of 4 in any category was determined, the patient was not considered to be a suitable candidate for percutaneous RFA. We assessed if the score of each category, safety score (P + O), and curability score (S + C + H) correlated with a safe and complete ablation using the chi-squared test and likelihood ratio test for trend. Results: The technical success rate was 100% (108/108) based on CT images obtained immediately after ablation. There was no 30-day mortality after RFA. There were major complications (one case of severe vasovagal reflex, one case of hemoperitoneum and one case of a pseudoaneurysm) in thrm and one case of a pseudoaneurysm) in three (2.7%) patients, and minor complications (one case of a biloma, one case of subsegmental infarction and one case of abscess) in three (2.7%) patients. Post-ablation syndrome as a side effect was noted in 38 (35.1%) of 108 patients. The primary technique effectiveness rate at 1 month was 95.1% (105/108). Local tumor progression was noted in eight (7.6%) of 105 patients during the follow-up period (range, 3.0-11.5 months; median, 5.8 months; mean, 5.7 months). There was no significant single category to predict complication and local tumor progression (Fisher's exact test, p > 0.05). Contrary to the safety score for the probability of complication (p > 0.05), the curability score was significantly associated with the probability of local tumor progression (likelihood ratio test for trend; p = 0.03). Conclusion: The new feasibility scoring system for planning US can be used as objective criteria to predict therapeutic efficacy rather than the safety of percutaneous RFA of an HCC.

218

NISS a Valuable Tool for Trauma Scoring on Autopsy  

OpenAIRE

A retrospective autopsy-based study conducted in correlation with the relevant clinical records and the reports from investigating agencies to analyze the suitability of Injury Severity Score (ISS) and New Injury Severity Score (NISS) in predicting the mortality of trauma victims. Four hundred and forty six autopsy reports of the victims of road traffic accidents were thoroughly studied and the external and internal injuries were assigned AIS coding. Based on this coding ISS and NISS scoring ...

Sharma, B. R.; Manisha Gupta; Sumedha Bangar

2005-01-01

219

Ki-67 expression score correlates to survival rate in gastrointestinal stromal tumors (GIST) / Escore de expressão de Ki-67 correlaciona-se com taxa de sobrevida em tumores estromais gastrointestinais (GIST)  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in portuguese OBJETIVO: Avaliar a expressão imunoistoquímica de p16, Ki-67, p53 e Bcl-2 proteínas em tumores gastrointestinais estromais (GIST); determinar a possível associação entre essas variáveis e fatores clínicos e histopatológicos de câncer, e para verificar o valor prognóstico destas variáveis (sobrevivên [...] cia e recorrência). MÉTODOS: Uma amostra de 55 pacientes tratados cirurgicamente para GIST em três hospitais foi estudada. Os tumores extirpados cirurgicamente foram confirmados como GIST por KIT, vimentina, proteína desmina S100, CD117, 1A4 e avaliação de CD34 em blocos de parafina. RESULTADOS: Apenas nove (16%) casos de GIST foram positivos para p53, p16 foi positiva em 43,6%, 80% dos GIST apresentaram coloração para Bcl-2. O índice proliferativo (expresso como a proporção de células positivas), avaliado pela expressão imunoistoquímica de Ki-67, foi elevado em 49% dos casos. Escores de Ki-67 elevados foram associados com alto grau histológico (p=0,0026) e índice de mitose, MI (p=0,0001). Alto índice de Ki-67 foi associado à morte. Expressão da p53, p16 e Bcl-2 não se correlacionou com as variáveis morfológicas ou clínicas. CONCLUSÕES: A avaliação imunoistoquímica de Ki-67 deve ser incluída na avaliação pré-operatória de biópsias ou peças cirúrgicas de GIST como uma ferramenta prognóstica para o estadiamento clínico, e todas as outras proteínas estudadas (Bcl-2, p53 e p16) não desempenharam um papel no processo metabólico ou carcinogênico em GIST, mantendo-se sem valor prognóstico. Abstract in english PURPOSE: To evaluate the immunohistochemical expression of p16, Ki-67, p53 and Bcl-2 proteins in gastrointestinal stromal tumors (GIST); to assess the possible association between these variables and clinical and histopathological factors of cancer; and to check for prognostic value of these variabl [...] es (survival and recurrence). METHODS: A sample of 55 patients treated surgically for GIST in three hospitals was studied. The surgically excised tumors were confirmed as GIST by KIT, vimentin, desmin S100 protein, CD117, 1A4 and CD34 assessment in paraffin blocks. RESULTS: Only 9 (16%) cases of GIST were positive for p53, p16 was positive among 43.6%; 80% of GISTs showed staining for Bcl-2. The proliferative index (expressed as the proportion of positive cells) assessed by immunohistochemical expression of Ki-67 was high in 49% of cases. Elevated Ki-67 scores were associated to high histological grade (p=0.0026) and mitosis index, MI (p=0.0001). High Ki-67 index was associated to death. Expression of p53, p16 and Bcl-2 did not correlate to morphological or clinical variables. CONCLUSIONS: Ki-67 immunohistochemical evaluation should be included in preoperative evaluation of GIST biopsies or surgical specimens as a prognostic tool for clinical staging; and all other proteins studied (Bcl-2, p53 and p16) did not play a role in GIST metabolic or carcinogenic process, remaining without prognostic value.

Ricardo, Artigiani Neto; Angela Flavia, Logullo; João Norberto, Stávale; Laércio Gomes, Lourenço.

2012-05-01

220

Ki-67 expression score correlates to survival rate in gastrointestinal stromal tumors (GIST Escore de expressão de Ki-67 correlaciona-se com taxa de sobrevida em tumores estromais gastrointestinais (GIST  

Directory of Open Access Journals (Sweden)

Full Text Available PURPOSE: To evaluate the immunohistochemical expression of p16, Ki-67, p53 and Bcl-2 proteins in gastrointestinal stromal tumors (GIST; to assess the possible association between these variables and clinical and histopathological factors of cancer; and to check for prognostic value of these variables (survival and recurrence. METHODS: A sample of 55 patients treated surgically for GIST in three hospitals was studied. The surgically excised tumors were confirmed as GIST by KIT, vimentin, desmin S100 protein, CD117, 1A4 and CD34 assessment in paraffin blocks. RESULTS: Only 9 (16% cases of GIST were positive for p53, p16 was positive among 43.6%; 80% of GISTs showed staining for Bcl-2. The proliferative index (expressed as the proportion of positive cells assessed by immunohistochemical expression of Ki-67 was high in 49% of cases. Elevated Ki-67 scores were associated to high histological grade (p=0.0026 and mitosis index, MI (p=0.0001. High Ki-67 index was associated to death. Expression of p53, p16 and Bcl-2 did not correlate to morphological or clinical variables. CONCLUSIONS: Ki-67 immunohistochemical evaluation should be included in preoperative evaluation of GIST biopsies or surgical specimens as a prognostic tool for clinical staging; and all other proteins studied (Bcl-2, p53 and p16 did not play a role in GIST metabolic or carcinogenic process, remaining without prognostic value.OBJETIVO: Avaliar a expressão imunoistoquímica de p16, Ki-67, p53 e Bcl-2 proteínas em tumores gastrointestinais estromais (GIST; determinar a possível associação entre essas variáveis e fatores clínicos e histopatológicos de câncer, e para verificar o valor prognóstico destas variáveis (sobrevivência e recorrência. MÉTODOS: Uma amostra de 55 pacientes tratados cirurgicamente para GIST em três hospitais foi estudada. Os tumores extirpados cirurgicamente foram confirmados como GIST por KIT, vimentina, proteína desmina S100, CD117, 1A4 e avaliação de CD34 em blocos de parafina. RESULTADOS: Apenas nove (16% casos de GIST foram positivos para p53, p16 foi positiva em 43,6%, 80% dos GIST apresentaram coloração para Bcl-2. O índice proliferativo (expresso como a proporção de células positivas, avaliado pela expressão imunoistoquímica de Ki-67, foi elevado em 49% dos casos. Escores de Ki-67 elevados foram associados com alto grau histológico (p=0,0026 e índice de mitose, MI (p=0,0001. Alto índice de Ki-67 foi associado à morte. Expressão da p53, p16 e Bcl-2 não se correlacionou com as variáveis morfológicas ou clínicas. CONCLUSÕES: A avaliação imunoistoquímica de Ki-67 deve ser incluída na avaliação pré-operatória de biópsias ou peças cirúrgicas de GIST como uma ferramenta prognóstica para o estadiamento clínico, e todas as outras proteínas estudadas (Bcl-2, p53 e p16 não desempenharam um papel no processo metabólico ou carcinogênico em GIST, mantendo-se sem valor prognóstico.

Ricardo Artigiani Neto

2012-05-01

221

Credit scores, cardiovascular disease risk, and human capital.  

Science.gov (United States)

Credit scores are the most widely used instruments to assess whether or not a person is a financial risk. Credit scoring has been so successful that it has expanded beyond lending and into our everyday lives, even to inform how insurers evaluate our health. The pervasive application of credit scoring has outpaced knowledge about why credit scores are such useful indicators of individual behavior. Here we test if the same factors that lead to poor credit scores also lead to poor health. Following the Dunedin (New Zealand) Longitudinal Study cohort of 1,037 study members, we examined the association between credit scores and cardiovascular disease risk and the underlying factors that account for this association. We find that credit scores are negatively correlated with cardiovascular disease risk. Variation in household income was not sufficient to account for this association. Rather, individual differences in human capital factors-educational attainment, cognitive ability, and self-control-predicted both credit scores and cardiovascular disease risk and accounted for ?45% of the correlation between credit scores and cardiovascular disease risk. Tracing human capital factors back to their childhood antecedents revealed that the characteristic attitudes, behaviors, and competencies children develop in their first decade of life account for a significant portion (?22%) of the link between credit scores and cardiovascular disease risk at midlife. We discuss the implications of these findings for policy debates about data privacy, financial literacy, and early childhood interventions. PMID:25404329

Israel, Salomon; Caspi, Avshalom; Belsky, Daniel W; Harrington, HonaLee; Hogan, Sean; Houts, Renate; Ramrakha, Sandhya; Sanders, Seth; Poulton, Richie; Moffitt, Terrie E

2014-12-01

222

Longitudinal Factor Score Estimation Using the Kalman Filter.  

Science.gov (United States)

How longitudinal factor score estimation--the estimation of the evolution of factor scores for individual examinees over time--can profit from the Kalman filter technique is described. The Kalman estimates change more cautiously over time, have lower estimation error variances, and reproduce the LISREL program latent state correlations more…

Oud, Johan H.; And Others

1990-01-01

223

Psychopathy scores and violence among juvenile offenders: a multi-measure study.  

Science.gov (United States)

This study examined the relations between psychopathy scores and violent behavior in 113 incarcerated adolescents. We compared the results of four different instruments designed to assess psychopathy features among juveniles-the Psychopathy Checklist: Youth Version (PCL:YV), two versions of the Antisocial Processes Screening Device (APSD), and a Psychopathy Content scale on the Millon Adolescent Clinical Inventory (MACI). We found that PCLY:YV scores were significantly correlated with violent offense history, unadjudicated violence, and institutional violence, as well as measures of the severity and instrumentality of prior violence. Receiver operating characteristic analyses generated statistically significant effect sizes (AUC values) ranging from 0.64 to 0.79. The three other measures generated statistically significant correlations with one or more of the violence criteria, although correlations and effect sizes tended to be smaller in magnitude. Our results offer some support for the validity of these measures of psychopathic features, and the value of the PCL:YV in particular, with respect to short-term measures of violence outcome among juvenile offenders. PMID:14963880

Murrie, Daniel C; Cornell, Dewey G; Kaplan, Sebastian; McConville, David; Levy-Elkon, Andrea

2004-01-01

224

Correlación entre las buenas prácticas de manufactura y el cumplimiento de los criterios microbiológicos en la fabricación de helados en Chile / Correlation between the good manufacturing practices and compliance with microbiological criteria in the manufacture of ice cream in Chile  

Scientific Electronic Library Online (English)

Full Text Available SciELO Chile | Language: Spanish Abstract in spanish Las Buenas Prácticas de Manufacturas (BPM) son una herramienta básica para obtener un producto alimenticio seguro para consumo humano. El objetivo de este estudio fue determinar el porcentaje de cumplimiento de BPM y su correlación con la aceptación de criterios microbiológicos en fábricas y muestra [...] s de helados de Ñuble, Chile, de acuerdo al Reglamento Sanitario de Alimentos chilenos. Se analizaron auditorías de BPM aplicadas por fiscalizadores de Secretaría Regional Ministerial (SEREMI) de Salud Ñuble, a 40 fábricas de helados y los resultados microbiológicos de 435 muestras de helados entre los años 2005 y 2010. Se determinó que el 55,2% de las muestras no cumplieron para RAM (105 UFC/g) y coliformes (102 UFC/g) y 4,6% para Staphylococcus aureus (102 UFC/g), en cambio el 100% cumplieron para Salmonella spp. Los mayores RAM fueron en verano con 60% de rechazo. El 67% de auditorías de BPM alcanzaron valores superiores al mínimo (70% de cumplimiento), las instalaciones fue el ítem mejor evaluado (88,4%), y capacitación del personal el peor (20,3 %). La correlación entre los resultados de auditorías de BPM y criterios microbiológicos permitió comprobar que con un porcentaje igual o superior al 80% de cumplimiento de BPM se aseguraría la calidad microbiológica de helados, disminuyendo con ello el riesgo en la salud del consumidor. Abstract in english The Good Manufacturing Practices (GMP) is a basic tool to obtain safe foodstuffs for human consumption. The main goal of this research was to determine the percentage of compliance with GMP in ice cream factories and its correlation with the acceptance of microbiological criteria in samples of ice c [...] ream, according to the Sanitary Chilean Food Regulation. Inspectors from the Ministerial Regional Secretariat (SEREMI) of Health Ñuble audited GMP in 40 ice cream factories and 435 microbial analyses from ice cream samples taken between the years 2005 and 2010 were analyzed. Results showed that 55.2% of samples failed in RAM (105 UFC/g) and coliform (102 UFC/g) and 4.6% for Staphylococcus aureus (102 UFC/g) and 100% for Salmonella spp. The biggest RAM was during summer with 60% rejection. Sixty seven% of inspections of GMP reached values above the minimum (70% compliance). Facilities were the best item assessed (88.4%), and training was the worst (20.3%). The correlation between the results of audits of GMP and microbiological criteria allowed proving that with a percentage equal to or greater than 80% compliance with GMP would ensure the microbiological quality of ice cream, thereby decreasing the risk for consumer health.

José Miguel, Bastías M; Marcela, Cuadra H; Ociel, Muñoz F; Roberto, Quevedo L.

2013-06-01

225

Prognostic criteria in acute pancreatitis: importance of assessment of pancreatic necrosis by contrast-enhanced CT  

International Nuclear Information System (INIS)

To compare the value of the clinical criteria of Ranson, the classical tomographic criteria of Balthzar and the severity of illness index according to CT in predicting the development of complications of acute pancreatitis. A retrospective study was performed in 100 patients with clinical and analytical evidence of acute pancreatitis. All patients were assessed according to Ranson score at admission and 48 hours later, and contrast-enhanced abdominal CT was carried out. The tomographic images were analyzed on the basis of the classical criteria of Balthazar and the new CT severity of illness index, which includes the assessment of pancreatic necrosis, identified as the areas of the pancreas that are not enhanced by the administration of the contrast material. These three criteria were then correlated with onset of medical and surgical implications. Our findings show that, of the three criteria analyzed, the CT severity of illness index presents the greatest specificity, sensitivity and positive and negative predictive values in the prediction of complications of acute pancreatitis. We conclude that the inclusion of pancreatic necrosis in the tomographic study improves the early assessment of the prognosis of acute pancreatitis. (Author) 20 refs

226

Criterios ecográficos diagnósticos de neoplasia maligna en el nódulo tiroideo: correlación con la punción por aspiración con aguja fina y la anatomía patológica / Ultrasound diagnostic criteria of malignancy in a thyroid nodule: correlation with fine needle aspiration and pathology  

Scientific Electronic Library Online (English)

Full Text Available SciELO Colombia | Language: Spanish Abstract in spanish Introducción. La ecografía de tiroides ha mejorado la certeza diagnóstica para neoplasia maligna del nódulo tiroideo. Es importante definir qué nódulos requieren biopsia por aspiración con aguja fina (BACAF) para disminuir el costo de un procedimiento innecesario y evitar que pase inadvertido el dia [...] gnóstico de neoplasia maligna. Objetivo. Validar los criterios ecográficos de neoplasia maligna que indican la punción por aspiración con aguja fina de tiroides. Materiales y métodos. Se diseñó un estudio prospectivo a tres años para evaluar la concordancia entre los hallazgos ecográficos y la punción por aspiración con aguja fina de tiroides comparada con el estudio final de histopatología. Se evaluó la sensibilidad, la especificidad, el valor diagnóstico positivo y negativo, la concordancia medida por el coeficiente kappa y el coeficiente de correlación. Resultados. Se estudiaron 1.467 pacientes, 10,2 % hombres y 89,8 % mujeres, con edades entre los 10 y los 95 años; el tamaño promedio del nódulo fue de 16 mm. Un total de 623 requirieron tiroidectomía; al resto se les hizo seguimiento por ecografía. Se presentaron 269 carcinomas papilares, 14 foliculares, 4 indiferenciados, 159 bocios, 74 adenomas y 101 tiroiditis. Se obtuvo sensibilidad de 86,4 %, especificidad de 89,4 %, valor diagnóstico de un resultado positivo de 87,5 % y uno negativo de 84,1 %. Los hallazgos ecográficos relacionados con cáncer fueron: hipoecogenicidad, microcalcificaciones, papilas y flujo intranodular. Individualmente, la concordancia fue baja, pero con la combinación de hipoecogenicidad, microcalcificaciones y papilas fue media y, con la adición de aumento del flujo intranodular, resultó alta. Conclusiones. La combinación de hipoecogenicidad, microcalcificaciones, papilas y alto flujo intranodular tiene alta concordancia con neoplasia maligna; sin embargo, cada criterio por separado no la tiene, y no pueden usarse individualmente para predecir o descartar neoplasia maligna. Abstract in english Introduction. Thyroid ultrasound has improved the diagnostic accuracy in the diagnosis of malignant neoplasia in thyroid nodules. It is important to define which nodules require fine needle aspiration so as to diminish the costs of unnecessary procedures and at the same time avoid unnoticed malignan [...] cy. Objective. To validate the echographic criteria of malignant neoplasia that validate fine needle aspiration of the thyroid nodule. Material and methods. Three-year prospective study to assess correlation between the ultrasound findings and fine needle aspiration with pathology findings, including sensibility, specificity, positive predictive value, negative predictive value, and concordance measured by Kappa coefficient, and correlation coefficient. Results. The study included 1,467 patients, 10,2% males and 89,8% females, with ages ranging from 10 years to 95 years; average size of the nodule was 16 mm; 623 patients required thyroidectomy, while the remainder were followed by ultrasound. There were 269 papillary carcinomas, 14 follicular carcinomas, 4 anaplastic carcinomas, 159 goiters, 74 adenomas, and 101 thyroiditis. Sensibility was 86,4%, specificity was 89,4%, positive predictive value 87,5%, and negative predictive value 84,1%. Ultrasound findings related with cancer were hypoechogenicity, microcalcifications, papillae, and intranodal flow; when adding intranodal flow, concordance was high. Conclusions. The combination of hypoechogenicity, microcalcifications, papillae and high intranodal flow exhibit high concordance with malignancy; however, echographic criteria considered individually does not, and those individual criteria cannot be used to predict or rule out malignant neoplasia.

Andrés Ignacio, Chala; Rafael, Pava; Humberto Ignacio, Franco; Andrés, Álvarez; Armando, Franco.

2013-03-01

227

Criterios ecográficos diagnósticos de neoplasia maligna en el nódulo tiroideo: correlación con la punción por aspiración con aguja fina y la anatomía patológica Ultrasound diagnostic criteria of malignancy in a thyroid nodule: correlation with fine needle aspiration and pathology  

Directory of Open Access Journals (Sweden)

Full Text Available Introducción. La ecografía de tiroides ha mejorado la certeza diagnóstica para neoplasia maligna del nódulo tiroideo. Es importante definir qué nódulos requieren biopsia por aspiración con aguja fina (BACAF para disminuir el costo de un procedimiento innecesario y evitar que pase inadvertido el diagnóstico de neoplasia maligna. Objetivo. Validar los criterios ecográficos de neoplasia maligna que indican la punción por aspiración con aguja fina de tiroides. Materiales y métodos. Se diseñó un estudio prospectivo a tres años para evaluar la concordancia entre los hallazgos ecográficos y la punción por aspiración con aguja fina de tiroides comparada con el estudio final de histopatología. Se evaluó la sensibilidad, la especificidad, el valor diagnóstico positivo y negativo, la concordancia medida por el coeficiente kappa y el coeficiente de correlación. Resultados. Se estudiaron 1.467 pacientes, 10,2 % hombres y 89,8 % mujeres, con edades entre los 10 y los 95 años; el tamaño promedio del nódulo fue de 16 mm. Un total de 623 requirieron tiroidectomía; al resto se les hizo seguimiento por ecografía. Se presentaron 269 carcinomas papilares, 14 foliculares, 4 indiferenciados, 159 bocios, 74 adenomas y 101 tiroiditis. Se obtuvo sensibilidad de 86,4 %, especificidad de 89,4 %, valor diagnóstico de un resultado positivo de 87,5 % y uno negativo de 84,1 %. Los hallazgos ecográficos relacionados con cáncer fueron: hipoecogenicidad, microcalcificaciones, papilas y flujo intranodular. Individualmente, la concordancia fue baja, pero con la combinación de hipoecogenicidad, microcalcificaciones y papilas fue media y, con la adición de aumento del flujo intranodular, resultó alta. Conclusiones. La combinación de hipoecogenicidad, microcalcificaciones, papilas y alto flujo intranodular tiene alta concordancia con neoplasia maligna; sin embargo, cada criterio por separado no la tiene, y no pueden usarse individualmente para predecir o descartar neoplasia maligna.Introduction. Thyroid ultrasound has improved the diagnostic accuracy in the diagnosis of malignant neoplasia in thyroid nodules. It is important to define which nodules require fine needle aspiration so as to diminish the costs of unnecessary procedures and at the same time avoid unnoticed malignancy. Objective. To validate the echographic criteria of malignant neoplasia that validate fine needle aspiration of the thyroid nodule. Material and methods. Three-year prospective study to assess correlation between the ultrasound findings and fine needle aspiration with pathology findings, including sensibility, specificity, positive predictive value, negative predictive value, and concordance measured by Kappa coefficient, and correlation coefficient. Results. The study included 1,467 patients, 10,2% males and 89,8% females, with ages ranging from 10 years to 95 years; average size of the nodule was 16 mm; 623 patients required thyroidectomy, while the remainder were followed by ultrasound. There were 269 papillary carcinomas, 14 follicular carcinomas, 4 anaplastic carcinomas, 159 goiters, 74 adenomas, and 101 thyroiditis. Sensibility was 86,4%, specificity was 89,4%, positive predictive value 87,5%, and negative predictive value 84,1%. Ultrasound findings related with cancer were hypoechogenicity, microcalcifications, papillae, and intranodal flow; when adding intranodal flow, concordance was high. Conclusions. The combination of hypoechogenicity, microcalcifications, papillae and high intranodal flow exhibit high concordance with malignancy; however, echographic criteria considered individually does not, and those individual criteria cannot be used to predict or rule out malignant neoplasia.

Andrés Ignacio Chala

2013-03-01

228

Molecular characterization of extended-spectrum beta-lactamases and its correlation with clinical laboratory standards institute interpretive criteria for disk diffusion susceptibility testing in enterobacteriaceae isolates in Thaialnd.  

Science.gov (United States)

We performed extended-spectrum beta-lactamase (ESBL) phenotypic testing and molecular characterization of three ESBL genes (TEM, SHV and CTX-M) and susceptibility testing by Clinical Laboratory Standards Institute (CLSI) disk diffusion method against three cephalosporins (ceftriaxone, ceftazidime, cefepime) and a cephamycin (cefoxitin) among 128 Thai Escherichia coli and 84 Thai Klebsiella pneumoniae clinical isolates. ESBL production was discovered in 62% of E. coli and 43% of K. pneumoniae isolates. All isolates susceptible to ceftriaxone were ESBL-negative. Nearly all isolates non-susceptible to ceftriaxone, ceftazidime and cefepime produced ESBL; the presence of CTX-M genes in the isolates correlated with a ceftriaxone non-susceptible phenotype. Thirty-nine of 83 isolates (47%) of ceftazidime-susceptible E. coli and 50 of 99 isolates (50.5%) of cefepime-susceptible E. coli were ESBL-producing. SHV-type beta-lactamase genes were more prevalent among K. pneumoniae than E. coli isolates. CTX-M was the major ESBL gene harbored by ESBL-producers in both E. coli and K. pneumoniae isolates. Non-CTX-M ESBL-producers were found only among K. pneumoniae isolates. This study reveals an increase in ESBL-producing Enterobacteriaceae among Thai isolates and demonstrates gaps in the current CLSI disk diffusion susceptibility guidelines; it indicates the results of ceftazidime and cefepime disk diffusion susceptibility testing using CLSI criteria should be interpreted with caution. PMID:23413710

Tangkoskul, Teerawit; Tiengrim, Surapee; Onsomang, Supiluck; Pati, Naratchaphan; Aswapokee, Nalinee; Thamlikitkul, Visanu; Chayakulkeeree, Methee

2012-11-01

229

Post-Anaesthetic Discharge Scoring System to assess patient recovery and discharge after colonoscopy  

OpenAIRE

AIM: To investigate whether discharge scoring criteria are as safe as clinical criteria for discharge decision and allow for earlier discharge. METHODS: About 220 consecutive outpatients undergoing colonoscopy under sedation with Meperidine plus Midazolam were enrolled and assigned to 2 groups: in Control-group (110 subjects) discharge decision was based on the clinical assessment; in PADSS-group (110 subjects) discharge decision was based on the modified Post-Anaesthetic Discharge Scoring Sy...

Lucio Trevisani; Viviana Cifalà; Giuseppe Gilli; Vincenzo Matarese; Angelo Zelante; Sergio Sartori

2013-01-01

230

Association between value-based purchasing score and hospital characteristics  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Medicare hospital Value-based purchasing (VBP program that links Medicare payments to quality of care will become effective from 2013. It is unclear whether specific hospital characteristics are associated with a hospital’s VBP score, and consequently incentive payments. The objective of the study was to assess the association of hospital characteristics with (i the mean VBP score, and (ii specific percentiles of the VBP score distribution. The secondary objective was to quantify the associations of hospital characteristics with the VBP score components: clinical process of care (CPC score and patient satisfaction score. Methods Observational analysis that used data from three sources: Medicare Hospital Compare Database, American Hospital Association 2010 Annual Survey and Medicare Impact File. The final study sample included 2,491 U.S. acute care hospitals eligible for the VBP program. The association of hospital characteristics with the mean VBP score and specific VBP score percentiles were assessed by ordinary least square (OLS regression and quantile regression (QR, respectively. Results VBP score had substantial variations, with mean score of 30 and 60 in the first and fourth quartiles of the VBP score distribution. For-profit status (vs. non-profit, smaller bed size (vs. 100–199 beds, East South Central region (vs. New England region and the report of specific CPC measures (discharge instructions, timely provision of antibiotics and beta blockers, and serum glucose controls in cardiac surgery patients were positively associated with mean VBP scores (p Conclusions Although hospitals serving the poor and the elderly are more likely to score lower under the VBP program, the correlation appears small. Profit status, geographic regions, number and type of CPC measures reported explain the most variation among scores.

Borah Bijan J

2012-12-01

231

Comparing Scoring and Fuzzy Logic Method for Teacher Certification DSS in Indonesia  

Directory of Open Access Journals (Sweden)

Full Text Available Graduation of teacher certification participants plays an important role in improving the quality of education in Indonesia. This paper presents a decision support system using a Scoring and Fuzzy Logic method to determine the participants graduation of teacher certification based on requirements fulfilled. Five criteria were used as the input of the system. In Fuzzy Logic method, each criteria is divided into three parts: low, medium and high; while scoring method is determined by using a 1 - 5 scale for each requirement fulfilled. Graduation and participants ranking using Scoring and Fuzzy Logic is the output of the system. In this paper, the assessment using Scoring and Fuzzy Logic showed different ranks and results in some scores, particularly in practice assessment by using scoring method for score 64,5 would not graduated the participants since the score of practice assessment is 65. While Fuzzy Logic would observe the scores of the four different methods, if those four criteria in the fuzzy were in high parts, then the participants graduated the tests. This means Fuzzy Logic more equitable to present decision and determine the ranks. In this paper was successful comparing Scoring and Fuzzy Logic method.

Ida Ayu Purnama Dewi

2012-11-01

232

Trauma Score - Retrospektive Evaluierung eines präklinisch erhobenen Scores  

OpenAIRE

Ziel der Studie: Score-Systeme dienen im wesentlich der Prognoseabschätzung eines Patienten, meist bezogen auf die Vorhersage des Überlebens oder Versterbens. Sie sind wichtige Instrumente, um die Effektivität und Qualität einer medizinischen Versorgung zu verstehen und zu überprüfen. Der Trauma Score (TS) wird, als wichtiger Vertreter der physiologischen Score-Systeme, nicht nur als Grundlage zur Triage und Prognoseabschätzung von Traumapatienten, sondern auch zur Bewertung ihrer Vers...

Jansen, Jochen

2004-01-01

233

Whole-Organ Arthroscopic Knee Score (WOAKS  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background To describe a semi-quantitative score for multi-feature, whole-organ evaluation of the knee in osteoarthritis based on the results of arthroscopic evaluation. Methods This was a study of 1,199 patients who were suffering from knee pain for over 3 months (range 3 to 48 months and had undergone arthroscopy. The mean age of patients was 49.8 (range 17 to 85 years old. Cartilage lesions were graded according to the ICRS protocol (grade 0 to 4 and for osteophytes "grade 5". Meniscus lesions were classified regarding to the extent of resection which was needed (grade 0: intact meniscus, grade 1: partial meniscectomy, grade 2: subtotal meniscectomy, and grade 3: total meniscectomy. The whole grade of cartilage lesions was calculated as the sum of ICRS grades in all joint surfaces (bearing and non-bearing margin. The whole grade of meniscus lesions was calculated as the sum of the points for medial and lateral meniscus surgery. The Whole-Organ Arthroscopic Knee Score (WOAKS was the sum of the cartilage and meniscus score. Results The mean knee osteoarthritis outcome score (KOOS of all patients was 67.3 ± 26.0 (range 21 to 128 points. The WOAKS was significantly associated (p = 0.001 with patient age (R = 0.399, the subjective complaints (R = 0.630 in KOOS, and the radiological grade of OA (R = 0.731. Conclusion The good correlation between the WOAKS and the subjective complaints as well as the radiological grade of OA suggests that the score can be used as an instrument for description of the "whole organ" knee. This score may be useful for clinical or epidemiological studies in the future.

Klinger Hans M

2008-11-01

234

Credit Scoring Modeling  

Directory of Open Access Journals (Sweden)

Full Text Available It is generally easier to predict defaults accurately if a large data set (including defaults is available for estimating the prediction model. This puts not only small banks, which tend to have smaller data sets, at disadvantage. It can also pose a problem for large banks that began to collect their own historical data only recently, or banks that recently introduced a new rating system. We used a Bayesian methodology that enables banks with small data sets to improve their default probability. Another advantage of the Bayesian method is that it provides a natural way for dealing with structural differences between a bank’s internal data and additional, external data. In practice, the true scoring function may differ across the data sets, the small internal data set may contain information that is missing in the larger external data set, or the variables in the two data sets are not exactly the same but related. Bayesian method can handle such kind of problem.

Siana Halim

2014-01-01

235

A scoring system for the assessment of angiographic findings in non-occlusive mesenteric ischemia (NOMI)  

International Nuclear Information System (INIS)

Purpose: To establish a standardized scoring system for angiographic findings in patients with non-occlusive mesenteric ischemia (NOMI). Materials and Methods: In 36 patients (mean age: 72 years), 53 angiographies of the superior mesenteric artery (SMA) were performed for suspected NOMI after cardiac or major aortic surgery. All examinations were performed using a standardized DSA technique. Two experienced radiologists performed a consensus reading blinded to the clinical information, on two occasions with an interval of two weeks. In order to investigate the reproducibility of the criteria, the images were assessed once by an intensivist and a medical student. Image analysis was performed with respect to vessel morphology, reflux of contrast medium into the aorta, small bowel parenchymal contrast enhancement and distension and the delay between arterial injection and portal vein filling. Results: Almost perfect intra-observer correlation was obtained for the assessment of the contrast medium reflux (? = 0.82) and substantial correlation for the time of portal vein filling (? = 0.66). Moderate correlations were obtained for the vessel morphology (? = 0.51), small bowel enhancement (? = 0.63) and distension (? = 0.53). Contrast medium reflux into the aorta (? = 0.77 and 0.63) and the time of portal vein filling (? = 0.42 and 0.58) resulted in the highest inter-observer correlations between the radiologists and the intensivist as well as the radiologists and theas well as the radiologists and the student. Conclusion: In patients with suspected NOMI, using our scoring system yields high intra- and inter-observer correlations, allowing a standardized evaluation of angiographic findings. (orig.)

236

Evidence of Disseminated Intravascular Coagulation in a Hemorrhagic Fever with Renal Syndrome—Scoring Models and Severe Illness  

Science.gov (United States)

Background Viral hemorrhagic fevers (VHF) are considered to be a serious threat to public health worldwide with up to 100 million cases annually. The general hypothesis is that disseminated intravascular coagulation (DIC) is an important part of the pathogenesis. The study objectives were to study the variability of DIC in consecutive patients with acute hemorrhagic fever with renal syndrome (HFRS), and to evaluate if different established DIC-scores can be used as a prognostic marker for a more severe illness. Method and Findings In a prospective study 2006–2008, data from 106 patients with confirmed HFRS were analyzed and scored for the presence of DIC according to six different templates based on criteria from the International Society on Thrombosis and Haemostasis (ISTH). The DIC-scoring templates with a fibrinogen/CRP-ratio were most predictive, with predictions for moderate/severe illness (p<0.01) and bleeding of moderate/major importance (p<0.05). With these templates, 18.9–28.3% of the patients were diagnosed with DIC. Conclusions DIC was found in about one fourth of the patients and correlated with a more severe disease. This supports that DIC is an important part of the pathogenesis in HFRS. ISTH-scores including fibrinogen/CRP-ratio outperform models without. The high negative predictive value could be a valuable tool for the clinician. We also believe that our findings could be relevant for other VHFs. PMID:21731657

Sundberg, Erik; Hultdin, Johan; Nilsson, Sofie; Ahlm, Clas

2011-01-01

237

Effects of two MMPI-2 validity scales on basic scale relations to external criteria.  

Science.gov (United States)

Many clinicians have come to rely on the broad array of validity scales available on the MMPI and the MMPI-2. In this study, we evaluated the utility of 2 MMPI-2 validity scales, the K scale and VRIN scale, in a sample of 692 psychiatric inpatients. Specifically, the effects of the K-correction procedure and the exclusion of protocols based on VRIN scale elevations were examined on the relation between MMPI-2 basic clinical scales and external criteria including both self-report and clinician ratings of psychopathology. Results indicated that the K-correction procedure commonly used with the MMPI and MMPI-2 did not result in higher correlations with external criteria in comparison to non-K-corrected scores. In contrast, MMPI-2 protocols that produced VRIN T-score values > or = 80 generally produced lower correlations with patients self-reports and clinician ratings of psychopathology in comparison to protocols judged to be valid based on VRIN scale results. PMID:9615425

Archer, R P; Fontaine, J; McCrae, R R

1998-02-01

238

Propensity score matching in SPSS  

OpenAIRE

Propensity score matching is a tool for causal inference in non-randomized studies that allows for conditioning on large sets of covariates. The use of propensity scores in the social sciences is currently experiencing a tremendous increase; however it is far from a commonly used tool. One impediment towards a more wide-spread use of propensity score methods is the reliance on specialized software, because many social scientists still use SPSS as their main analysis tool. Th...

Thoemmes, Felix

2012-01-01

239

A clinical score to reduce unnecessary antibiotic use in patients with sore throat  

OpenAIRE

OBJECTIVE: To validate a score based on clinical symptoms and signs for the identification of group A Streptococcus (GAS) infection in general practice patients with score throat. DESIGN: A single throat swab was used as the gold standard for diagnosing GAS infection. Clinical information was recorded by experienced family physicians on standardized encounter forms. Score criteria were identified by means of logistic regression modelling of data from patients enrolled in the first half of the...

Mcisaac, W. J.; White, D.; Tannenbaum, D.; Low, D. E.

1998-01-01

240

Validating MMI scores: are we measuring multiple attributes?  

Science.gov (United States)

The multiple mini-interview (MMI) used in health professional schools' admission processes is reported to assess multiple non-cognitive constructs such as ethical reasoning, oral communication, or problem evaluation. Though validation studies have been performed with total MMI scores, there is a paucity of information regarding how well MMI scores differentiate the constructs being measured, the relationship between MMI scores (construct or total) and personality characteristics, and how well MMI scores (construct or total) predict future performance in practice. Results from these studies could assist with MMI station development, rater training, score interpretation, and resource allocation. The purpose of this study was to investigate the validity of MMI construct scores (oral communication and problem evaluation), and their relationship to personality measures (emotionality and extraversion) and specific scores from standardized clinical communications interviews (building the relationship and explaining and planning). Confirmatory factor analysis results support a two factor MMI model, however the correlation between these factors was .87. Oral communication MMI scores significantly correlated with extraversion (r c = .25, p rubrics for attributes identified as important for future success in school and practice. PMID:24449121

Oliver, Tom; Hecker, Kent; Hausdorf, Peter A; Conlon, Peter

2014-08-01

241

Ranson?s criteria for acute pancreatitis in high altitude: Do they need to be modified?  

Directory of Open Access Journals (Sweden)

Full Text Available Background/Aim: To examine the validity of Ranson?s criteria in the prediction of the severity of acute pancreatitis (as judged by the occurrence of complications in a high-altitude area of Saudi Arabia with a predominant biliary pancreatitis. Materials and Methods: All consecutive cases of acute pancreatitis (AP admitted to a tertiary care hospital over a two-and-half-year period were included in this prospective study. Ranson?s criteria (RC were used to determine the severity of the attack of AP, which was then correlated with the occurrence of complications. The validity of Ranson?s score and that of each of its individual components was estimated. Using receiver operating characteristic (ROC curve, new optimum values for these components were calculated and a new modified score was constructed. Results: Seventy-three attacks of AP in 69 patients formed the material of this study. Ranson?s prediction criteria classified 43.8% of the attacks as "severe", but only 22% of those attacks were associated with complications. Calcium level (< 8 mg/dl was the only criterion that was significantly associated with complications (Kappa = 0.32, p0 = 0.02. Using ROC curve to determine the optimum cut-off levels for prediction identified only four criteria, which were significantly associated with complications as compared with the original Ranson?s cut-off levels. Those were: a serum glucose value of ?160 mg/dl ( P < 0.05, blood urea nitrogen rise of ?35 mg/dl ( P < 0.02 and an arterial Po 2 value of ?55 mm Hg ( P < 0.01, in addition to calcium value of < 8 mg/dl ( P = 0.02 as originally set by Ranson. A new scoring system, ranging from 0 to 4, based on these cut-off levels, together with a calcium level of < 8 mg/dl, could correctly classify the severity of AP. A total score of two or more points predicted a severe attack with a sensitivity of 88%, a specificity of 82% and a Kappa coefficient of 0.47 ( P < 0.001. Conclusion: This study showed that Ranson?s criteria may need to be modified in high altitude with a predominant biliary pancreatitis in order to accurately predict the severity of AP.

Abu-Eshy Saeed

2008-01-01

242

Análise bayesiana na estimação de correlações genéticas entre escores visuais e características reprodutivas de bovinos Nelore utilizando modelos linear-limiar / Bayesian analysis in the estimation of genetic correlations between visual scores and reproductive traits in Nelore cattle using linear-threshold models  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese Estimaram-se as correlações genéticas entre os escores visuais e as características reprodutivas, utilizando a estatística bayesiana sob modelo animal linear-limiar, em bovinos da raça Nelore. Foram estudadas características categóricas morfológicas, avaliadas visualmente aos oito, 15 e 22 meses de [...] idade; e características contínuas de perímetro escrotal padronizado aos 365 e 450 dias de idade, além da idade ao primeiro parto. As estimativas de correlações genéticas foram de sentido favorável à seleção, apresentando magnitudes moderadas, sugerindo que a seleção de animais para um biótipo desejável pode levar a animais com maior fertilidade e precocidade sexual. As estimativas de correlação genética para o perímetro escrotal padronizado aos 450 dias e a idade ao primeiro parto com as características morfológicas avaliadas aos 22 meses de idade foram maiores do que as obtidas entre as características de escores visuais avaliadas aos oito e 15 meses de idade. A utilização de escores visuais como critério de seleção trará progresso genético também para as características reprodutivas. Abstract in english The genetic correlations between visual scores and reproductive traits, using the bayesian statistic under the linear-threshold animal model, in bovines of the Nelore breed were estimated. Categorical morphological traits were also evaluated at eight, 15, and 22 month-old, concerning musculature, ph [...] ysical structure, conformation and sacrum, the escrotal circumferences measured at the ages of 365 and 450-day-old, and the age at first calving. The estimates of genetic correlations were moderates, suggesting that the selection of animals with better morphological conformation may lead to animals more precocious and with greater fertility. The estimates of genetic correlation concerning the escrotal circumference at 450 day-old and the age at first calving with the evaluated visual scores at 22 month-old were higher than the ones obtained between visual scores at eight and 15 month-old. The use of these visual scores as a criterion of selection may also bring genetic progress to the reproductive traits.

C.U., Faria; C.U., Magnabosco; L.G., Albuquerque; A., de los Reyes; L.A.F., Bezerra; R.B., Lôbo.

2009-08-01

243

Influence of low-stress handling on reactivity score and pregnancy rate during fixed-time artificial insemination in Nellore cows  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in english The objective of this work was to evaluate the influence of low-stress handling (LSH) on reactivity score and pregnancy rate during fixed-time artificial insemination (FTAI) for extensively raised Nellore cows. Multiparous cows (n = 126) were randomly allocated into two groups: G1 (n = 66) and G2, t [...] he control group (n = 60). Group G1 was subjected to LSH, in which the animals were handled in a calm and quiet manner, without loud noises or physical aggression, using the point of balance, respecting the flight zone and using flags to supplement handling. Group G2 was handled following the typical procedure, with yelling, kicking and the use of electric prods and sticks. On D0, D8 and D10, FTAI was performed in both groups. Reactivity was scored on D0, D8 and D10 at the squeeze chute, based on the tension score, breathing score, and bellowing score. Using the three criteria above, the reactivity scores were defined as follows: R1 (calm); R2 (slightly reactive); R3 (moderately reactive); R4 (reactive); and R5 (highly reactive). Thirty-five days after artificial insemination, pregnancy was determined using ultrasonography. There was no significant correlation between reactivity score and pregnancy rate in each group or between the pregnancy rates in both groups. However, there was a statistically significant difference between the G1 and G2 groups with regard to reactivity score (1.62±0.05 vs. 2.12±0.07). Low-stress handling influenced reactivity but did not affect pregnancy rate in extensively raised Nellore cows subjected to FTAI.

Rayf Roberto, Tirloni; Fábio Alcântara, Rocha; Fábio José, Lourenço; Lílian Rigatto, Martins.

2013-07-01

244

Comparação entre três escores embrionários como fator prognóstico do sucesso em fertilização in vitro Comparison between three embryo scoring systems as predictive of the outcome of in vitro fertilization  

Directory of Open Access Journals (Sweden)

Full Text Available OBJETIVO: avaliar três sistemas de escore embrionário para embriões de 3º dia e correlacioná-los com resultados positivos da técnica de fertilização in vitro. MÉTODO: estudo retrospectivo desenvolvido pelo programa de fertilização in vitro do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto - USP. Foram incluídas 137 pacientes submetidas a fertilização in vitro e transferência de 439 embriões. Os principais resultados avaliados foram taxa de gravidez e taxa de implantação. RESULTADOS: nos três métodos observou-se diferença significativa no escore embrionário entre o grupo de grávidas (n=53 e não grávidas (n=84 (pPURPOSE: to evaluate three embryo scoring systems specific for 3-day embryos and to correlate them with positive in vitro fertilization outcome. METHOD: retrospective study of the In Vitro Fertilization Program of the University Hospital, Faculty of Medicine of Ribeirão Preto, University of São Paulo. A total of 137 patients submitted to the transfer of 439 embryos were evaluated. The main outcomes measured were pregnancy and implantation rates. RESULTS: a significant difference in the three scoring systems was observed between pregnant (n=53 and non-pregnant (n=84 patients (p<0.0001. In the first embryo scoring system, in which cell number alone was used, higher pregnancy (70% and implantation rates (42% were observed when embryos with a mean blastomere number higher than 8 were transferred. Scoring system 2, based on a total four-point score (cleavage stage, blastomere number, fragmentation and symmetry, showed increased pregnancy (52.8% and implantation rates (31% for scores above 2. Scoring system 3, based on cell number and morphological criteria, also showed higher pregnancy and implantation rates with increasing average scores of the transferred embryos. CONCLUSION: the three scoring systems assessed in 3-day embryos were positively correlated with pregnancy and implantation rates.

Marcos Dias de Moura

2003-04-01

245

TS-Chemscore, a Target-Specific Scoring Function, Significantly Improves the Performance of Scoring in Virtual Screening.  

Science.gov (United States)

Most of the scoring functions currently used in structure-based drug design belong to 'universal' scoring functions, which often give a poor correlation between the calculated scores and experimental binding affinities. In this investigation, we proposed a simple strategy to construct target-specific scoring functions based on known 'universal' scoring functions. This strategy was applied to Chemscore, a widely used empirical scoring function, which led to a new scoring function, termed TS-Chemscore. TS-Chemscore was validated on 14 protein targets, which cover a wide range of biological target categories. The results showed that TS-Chemscore significantly improved the correlation between the calculated scores and experimental binding affinities compared with the original Chemscore. TS-Chemscore was then applied in virtual screening to retrieve novel JAK3 and YopH inhibitors. Top 30 compounds for each target were selected for experimental validation. Six active compounds for JAK3 and four for YopH were obtained. These compounds were out of the lists of top 30 compounds sorted by Chemscore. Collectively, TS-Chemscore established in this study showed a better performance in virtual screening than its counterpart Chemscore. PMID:25358259

Wang, Wen-Jing; Huang, Qi; Zou, Jun; Li, Lin-Li; Yang, Sheng-Yong

2014-10-31

246

Skyrocketing Scores: An Urban Legend  

Science.gov (United States)

A new urban legend claims, "As a result of the state dropping bilingual education, test scores in California skyrocketed." Krashen disputes this theory, pointing out that other factors offer more logical explanations of California's recent improvements in SAT-9 scores. He discusses research on the effects of California's Proposition 227, which…

Krashen, Stephen

2005-01-01

247

International Validation of the Low Anterior Resection Syndrome Score  

DEFF Research Database (Denmark)

OBJECTIVE:: The aims of this study were to investigate the convergent and discriminative validity and reliability of the low anterior resection syndrome (LARS) score in an international setting. BACKGROUND:: The LARS score is a simple self-administered questionnaire measuring bowel dysfunction after rectal cancer surgery. The score is intended to be commonly used in international research and clinical practice in the future. Therefore, a thorough validation in an international setting is of utmost importance. METHODS:: The LARS score was translated using methods in keeping with current international recommendations. A total of 801 patients operated for rectal cancer in Sweden, Spain, Germany, and Denmark completed the LARS score questionnaire, including an anchor question assessing the impact of bowel function on quality of life. A subgroup of 218 patients completed the LARS score twice. Data were analyzed per country. RESULTS:: The LARS score has demonstrated a high convergent validity in terms of a high correlation between LARS score and quality of life (P <0.001). Sensitivity ranged from 67.7% to 88.3% and specificity from 58.1% to 86.3%. The LARS score was able to discriminate between groups of patients differing with regard to radiotherapy, surgery, and age (P <0.05). The score also demonstrated high reliability at test-retest with narrow limits of agreement and no statistically significant difference between scores at the first and second test. CONCLUSIONS:: The Swedish, Spanish, German, and Danish versions of the LARS score have proven to be valid and reliable tools for measuring LARS in European rectal cancer patients.

Juul, Therese; Ahlberg, Madelene

2013-01-01

248

Estimating WISC-III Scores for Special Education Students Using the Dumont-Faro Short Form.  

Science.gov (United States)

Uses the Dumont-Faro short form to estimate the Wechsler Intelligence Scales for Children-III (WISC-III) Full Sale IQ scores for 45 special education students. Results demonstrate that IQ scores were positively correlated with the WISC-III Full Scale scores. However an IQ miscalculation rate of 44% challenges the utility of the Dumont-Faro short…

Comninel, Mary E.; Bordieri, James E.

2001-01-01

249

The Relationship between Admission Criteria and Fieldwork Performance in a Masters-Level OT Program: Implications for Admissions  

Directory of Open Access Journals (Sweden)

Full Text Available Occupational therapy (OT graduate programs strive to produce an effective OT workforce with competent and engaged OT practitioners. Admission into OT graduate programs is an increasingly competitive process, with most programs having more applicants than spaces available. Programs need to select applicants that will be the most successful in meeting graduation requirements, including both academic and clinical components. This pilot study was designed to examine the relationship between admission criteria and fieldwork (FW performance. The study utilized a retrospective analysis with a convenience sample of 108 students with complete data from a private university in the Midwest. Independent variables of Graduate Record Examination (GRE subscale scores (GRE-verbal, GRE-quantitative, and GRE-written and undergraduate Cumulative Grade Point Average (CGPA were included. The dependent variable was level II FW performance, as measured by the AOTA Fieldwork Performance Evaluation (FWPE. Results of this study found a significant correlation between CGPA and FWPE scores for level IIA FW experiences, and a significant correlation between GRE-written and FWPE scores for level IIB FW experiences. Regression models for FW IIB indicated that GRE-written was a significant predictor of FWPE scores for the FW IIB experience. This pilot study provides information that may be utilized during OT admission processes.

Molly Bathje MS, OTR/L

2014-07-01

250

Clinical performance of two visual scoring systems in detecting and assessing activity status of occlusal caries in primary teeth  

DEFF Research Database (Denmark)

This study aimed to compare the clinical performance of two sets of visual scoring criteria for detecting caries severity and assessing caries activity status in occlusal surfaces. Two visual scoring systems--the Nyvad criteria (NY) and the ICDAS-II including an adjunct system for lesion activity assessment (ICDAS-LAA)--were compared using 763 primary molars of 139 children aged 3-12 years. The examinations were performed by 2 calibrated examiners. A subsample (n = 50) was collected after extraction and histology with 0.1% red methyl dye was performed to validate lesion depth and activity. The reproducibility of the indices was calculated (kappa test) and ROC analysis was performed to assess their validity and related parameters were compared using McNemar's test. The association between the indices and with the histological examination was evaluated using Spearman's correlation coefficient (r(s)). Visual criteria showed excellent reproducibility both regarding severity (NY: 0.94; ICDAS-II: 0.91) and activity(NY: 0.90; LAA: 0.91). The NY and LAA showed good association in caries activity assessment (r(s) = 0.88; 95% CI = 0.86-0.89; p 0.05). Concerning the severity, both indices presented similar validity parameters. At D2 threshold, the sensitivity was higher for NY (NY = 0.87; ICDAS = 0.61, p <0.05). Regarding activity status, NY showed higher specificities and accuracies. In conclusion, NY and ICDAS-II criteria are comparable and present good reproducibility and validity to detect caries lesions and estimate their severities, but the LAA seems to overestimate the caries activity assessment of cavitated lesions compared to NY.

Braga, M M; Ekstrand, K R

2010-01-01

251

Neurointerventional Treatment in Acute Stroke. Whom to Treat? (Endovascular Treatment for Acute Stroke: Utility of THRIVE Score and HIAT Score for Patient Selection)  

Energy Technology Data Exchange (ETDEWEB)

Purpose: Intra-arterial therapy (IAT) is used increasingly as a treatment option for acute stroke caused by central large vessel occlusions. Despite high rates of recanalization, the clinical outcome is highly variable. The authors evaluated the Houston IAT (HIAT) and the totaled health risks in vascular events (THRIVE) score, two predicting scores designed to identify patients likely to benefit from IAT. Methods: Fifty-two patients treated at the Stavanger University Hospital with IAT from May 2009 to June 2012 were included in this study. We combined the scores in an additional analysis. We also performed an additional analysis according to high age and evaluated the scores in respect of technical efficacy. Results: Fifty-two patients were evaluated by the THRIVE score and 51 by the HIAT score. We found a strong correlation between the level of predicted risk and the actual clinical outcome (THRIVE p = 0.002, HIAT p = 0.003). The correlations were limited to patients successfully recanalized and to patients <80 years. By combining the scores additional 14.3 % of the patients could be identified as poor candidates for IAT. Both scores were insufficient to identify patients with a good clinical outcome. Conclusions: Both scores showed a strong correlation to poor clinical outcome in patients <80 years. The specificity of the scores could be enhanced by combining them. Both scores were insufficient to identify patients with a good clinical outcome and showed no association to clinical outcome in patients aged {>=}80 years.

Fjetland, Lars, E-mail: lars.fjetland@lyse.net; Roy, Sumit, E-mail: sumit.roy@sus.no; Kurz, Kathinka D., E-mail: kathinka.dehli.kurz@sus.no [Stavanger University Hospital, Department of Radiology (Norway); Solbakken, Tore, E-mail: tore.solbakken@sus.no [Stavanger University Hospital, Department of Neurology (Norway); Larsen, Jan Petter, E-mail: jan.petter.larsen@sus.no; Kurz, Martin W., E-mail: martin.kurz@sus.no [The Norwegian Center for Movement Disorders, Stavanger University Hospital (Norway)

2013-10-15

252

Neurointerventional Treatment in Acute Stroke. Whom to Treat? (Endovascular Treatment for Acute Stroke: Utility of THRIVE Score and HIAT Score for Patient Selection)  

International Nuclear Information System (INIS)

Purpose: Intra-arterial therapy (IAT) is used increasingly as a treatment option for acute stroke caused by central large vessel occlusions. Despite high rates of recanalization, the clinical outcome is highly variable. The authors evaluated the Houston IAT (HIAT) and the totaled health risks in vascular events (THRIVE) score, two predicting scores designed to identify patients likely to benefit from IAT. Methods: Fifty-two patients treated at the Stavanger University Hospital with IAT from May 2009 to June 2012 were included in this study. We combined the scores in an additional analysis. We also performed an additional analysis according to high age and evaluated the scores in respect of technical efficacy. Results: Fifty-two patients were evaluated by the THRIVE score and 51 by the HIAT score. We found a strong correlation between the level of predicted risk and the actual clinical outcome (THRIVE p = 0.002, HIAT p = 0.003). The correlations were limited to patients successfully recanalized and to patients <80 years. By combining the scores additional 14.3 % of the patients could be identified as poor candidates for IAT. Both scores were insufficient to identify patients with a good clinical outcome. Conclusions: Both scores showed a strong correlation to poor clinical outcome in patients <80 years. The specificity of the scores could be enhanced by combining them. Both scores were insufficient to identify patients with a good clinical outcome and showed no association to clinical outcome in patients aged ?80 years

253

Diagnostic Value of Amsel's Clinical Criteria for Diagnosis of Bacterial Vaginosis  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction: Bacterial vaginosis (BV is one of the most prevalent infections in women of reproductive age. Amsel’s criteria and Nugent scoring system are among the most commonly used diagnostic methods. Although Nugent scoring system is considered the gold standard for diagnosing BV, it is time consuming and costly, and its interpretation needs lab equipment and experts. Hence, most physicians are inclined to use simpler clinical criteria that are yet accurate instead.The present study aimed to determine the diagnostic value of Amsel’s criteria in diagnosing BV. Material and Methods: This present study was conducted to validate diagnostic tests of BVin 120 married women in 2013. Amsel’s criteria and Nugent scoring system were used to diagnose BV. Nugent scoring system was considered the gold standard and sensitivity, specificity, positive predictive value and negative predictive value of Amsel’s criteria were compared with those of Nugent scoring system. Results: Kappa coefficient was used to assess the diagnostic value of Nugent scoring system and Amsel’s criteria. Kappa coefficient was found 0.8, which confirms the reliability of both diagnostic methods. McNemar test did not reveal a significant difference between Nugent scoring system and Amsel’s criteria in terms of diagnosing BV. As compared to Nugent scoring system, Asmel’s criteria enjoy sensitivity of 0.91, specificity of 0.91, positive predictive value of 0.86, negative predictive value of 0.94, and accuracy of 0.91. Conclusion: If lab equipment is not available for diagnosing BV, Amsel’s criteria can be as good as Nugent scoring system at diagnosing this infection.

Farnaz Mohammadzadeh

2014-10-01

254

Grado de correlación en la percepción de la dinámica familiar entre ambos padres de preescolares que acuden a Guarderías del DIF Jalisco / Correlation of the family dinamic score between fathers and mothers of preschool children attending the integral development of the family system (DIF) of Guadalajara, Jalisco (Mexico)  

Scientific Electronic Library Online (English)

Full Text Available SciELO Mexico | Language: Spanish Abstract in spanish Introducción. Objetivo: identificar la correlación entre la calificación de dinámica familiar de papá y mamá de preescolares que acuden a Guarderías del Sistema Nacional del Desarrollo Integral de la Familia Jalisco. Material y métodos. Estudio transversal analítico. Se incluyeron 138 encuestas de d [...] inámica familiar aplicadas a ambos padres. Se utilizó un instrumento de medición con 8 áreas: I. Dinámica de pareja; II. Formación de identidad; III. Comunicación, expresión, solidaridad; IV. Estructura de autoridad; V. Manejo del conflicto y agresividad;VI. Disciplina y método; VII. Sistema de Valores; VIII.Aislamiento e integración sociocultural. Resultados. No hubo diferencia en la calificación entre ambos padres ni entre los promedios de las 8 áreas. Hubo una correlación significativa entre ambos padres (r = 0.759, P Abstract in english Introduction. Objective: to test the correlation of the family dynamic score between fathers and mothers of preschool children attending the Integral Development of the Family System (DIF) of Guadalajara City. Material and methods. In a cross sectional study design 140 family dynamic surveys were in [...] cluded. Eight areas of the dynamic of the family of both parents were explored: I. Dynamic of the couple; II. Formation of identity; III. Communication, expression and solidarity; IV. Structure of the authority;V. Management of the conflict and aggressiveness;VI. Discipline and method;VII. System of values;VIII. Socio cultural integration and isolation. Results. There were not differences between fathers and mothers in the eight explored areas.The score of fathers and mothers had a significant correlation (r =0.759). Area I had the higher correlation with the rest of the areas (P

Francisco, Nápoles-Rodríguez; Angélica, Cevallos-González; Eva, Sánchez-Talamantes; José Luis, González-Rico; Enrique, Romero-Velarde; Edgar M., Vásquez-Garibay.

2005-06-01

255

Association between eating behavior scores and obesity in Chilean children  

OpenAIRE

Abstract Background Inadequate eating behavior and physical inactivity contribute to the current epidemic of childhood obesity. The aim of this study was to assess the association between eating behavior scores and childhood obesity in Chilean children. Design and methods We recruited 126 obese, 44 overweight and 124 normal-weight Chilean children (6-12 years-old; both genders) according to the International Obesity Task Force (IOTF) criteria. Eating behavior sc...

Amador Paola; Obregón Ana M; Cataldo Rodrigo; Domínguez-Vásquez Patricia; Smalley Susan V; González Andrea; Ho-Urriola Judith A; Santos José L; Weisstaub Gerardo; Isabel, Hodgson M.

2011-01-01

256

Unified EEG terminology and criteria for nonconvulsive status epilepticus  

DEFF Research Database (Denmark)

The diagnosis of nonconvulsive status epilepticus (NCSE) relies largely on electroencephalography (EEG) findings. The lack of a unified EEG terminology, and of evidence-based EEG criteria, leads to varying criteria for and ability to diagnose NCSE. We propose a unified terminology and classification system for NCSE, using, as a template, the Standardised Computer-based Organised Reporting of EEG (SCORE). This approach integrates the terminology recently proposed for the rhythmic and periodic patterns in critically ill patients, the electroclinical classification of NCSE (type of NCSE) and the context for the pathologic conditions and age-related epilepsy syndromes. We propose flexible EEG criteria that employ the SCORE system to assemble a database for determining evidence-based EEG criteria for NCSE.

Beniczky, Sándor; Hirsch, Lawrence J

2013-01-01

257

Optimal Utilization of Donor Grafts With Extended Criteria  

Science.gov (United States)

Objective: Severely limited organ resources mandate maximum utilization of donor allografts for orthotopic liver transplantation (OLT). This work aimed to identify factors that impact survival outcomes for extended criteria donors (ECD) and developed an ECD scoring system to facilitate graft-recipient matching and optimize utilization of ECDs. Methods: Retrospective analysis of over 1000 primary adult OLTs at UCLA. Extended criteria (EC) considered included donor age (>55 years), donor hospital stay (>5 days), cold ischemia time (>10 hours), and warm ischemia time (>40 minutes). One point was assigned for each extended criterion. Cox proportional hazard regression model was used for multivariate analysis. Results: Of 1153 allografts considered in the study, 568 organs exhibited no extended criteria (0 score), while 429, 135 and 21 donor allografts exhibited an EC score of 1, 2 and 3, respectively. Overall 1-year patient survival rates were 88%, 82%, 77% and 48% for recipients with EC scores of 0, 1, 2 and 3 respectively (P < 0.001). Adjusting for recipient age and urgency at the time of transplantation, multivariate analysis identified an ascending mortality risk ratio of 1.4 and 1.8 compared to a score of 0 for an EC score of 1, and 2 (P < 0.01) respectively. In contrast, an EC score of 3 was associated with a mortality risk ratio of 4.5 (P < 0.001). Further, advanced recipient age linearly increased the death hazard ratio, while an urgent recipient status increased the risk ratio of death by 50%. Conclusions: Extended criteria donors can be scored using readily available parameters. Optimizing perioperative variables and matching ECD allografts to appropriately selected recipients are crucial to maintain acceptable outcomes and represent a preferable alternative to both high waiting list mortality and to a potentially futile transplant that utilizes an ECD for a critically ill recipient. PMID:16772778

Cameron, Andrew M.; Ghobrial, R Mark; Yersiz, Hasan; Farmer, Douglas G.; Lipshutz, Gerald S.; Gordon, Sherilyn A.; Zimmerman, Michael; Hong, Johnny; Collins, Thomas E.; Gornbein, Jeffery; Amersi, Farin; Weaver, Michael; Cao, Carlos; Chen, Tony; Hiatt, Jonathan R.; Busuttil, Ronald W.

2006-01-01

258

What Is the Apgar Score?  

Science.gov (United States)

... Lower Apgar scores are also seen in premature babies , who usually have less muscle tone than full-term newborns and who, in many cases, will need extra monitoring and breathing help because of their immature lungs. ...

259

Maximum-Score Diversity Selection  

OpenAIRE

Diese Dissertation behandelt das Maximum-Score Diversity Selection (MSDS) Problem. Reine Diversitätsauswahl, wie sie bereits häufig z.B. in der frühen Wirkstoffforschung in der Pharmaindustrie eingesetzt wird, ist die Auswahl einer Teilmenge von Objekten die möglichst divers ist. MSDS führt ein zweites Kriterium ein, das neben der Optimierung der Diversität, auch die Bewertung ("score'') der Teilmenge optimieren soll (in der Regel die Summe der Bewertungen der einzelnen Objekte). Diese ...

Meinl, Thorsten

2010-01-01

260

Disease Severity Indexes and Treatment Evaluation Criteria in Vitiligo  

OpenAIRE

There is a current lack of consensus regarding methods of assessment of vitiligo. Recently, the Vitiligo Area Scoring Index (VASI) and the Vitiligo European Task Force (VETF) were proposed to offer more accurate measures of disease severity indexes and treatment evaluation criteria. It would make sense to combine the VASI with the VETF system. We proposed an original scale for treatment evaluation criteria in vitiligo based on VASI. We plan to add the digital image analysis system, health-rel...

Tamihiro Kawakami; Takashi Hashimoto

2011-01-01

261

The examination of the relationship between YGS scores and music field scores in music teaching programme with special talent examination  

OpenAIRE

Every year, with special aptitude exams students are taken to undergraduate programs as a music teacher in Turkey .Although applications for these exam show differences according to the difficulty level of the questions and evaluations criterias, all the areas that would be measured show similarities to each other. The areas showing the similarity are classified as Musical hearing-reading-writing fields (M?OY) , musical playing area and musical singing area. Special Ability Test score (ÖY...

Turan Sa?er; Onur Zahal; Engin Gürp?nar

2013-01-01

262

Numerical scoring of treatment plans  

International Nuclear Information System (INIS)

This is a report on numerical scoring techniques developed for the evaluation of treatment plans as part of a four-institution study of the role of 3-D planning in high energy external beam photon therapy. A formal evaluation process was developed in which plans were assessed by a clinician who displayed dose distributions in transverse, sagittal, coronal, and arbitrary oblique planes, viewed dose-volume histograms which summarized dose distributions to target volumes and the normal tissues of interest, and reviewed dose statistics which characterized the volume dose distribution for each plan. In addition, tumor control probabilities were calculated for each biological target volume and normal tissue complication probabilities were calculated for each normal tissue defined in the agreed-upon protocols. To score a plan, the physician assigned a score for each normal tissue to reflect possible complications; for each target volume two separate scores were assigned, one representing the adequacy of tumor coverage, the second the likelihood of a complication. After scoring each target and normal tissue individually, two summary scores were given, one for target coverage, the second reflecting the impact on all normal tissues. Finally, each plan was given an overall rating (which could include a downgrading of the plan if the treatment was judged to be overly complex)

263

Scoring clinical competencies of learners: A quantitative descriptive study  

Scientific Electronic Library Online (English)

Full Text Available SciELO South Africa | Language: English Abstract in english This article reports the correlation between different clinical assessors' scoring of learners' clinical competencies in order to exclude any possible extraneous variables with regard to reasons for poor clinical competencies of learners. A university in Gauteng, South Africa provides a learning pro [...] gramme that equips learners with clinical knowledge, skills and values in the assessment, diagnosis, treatment and care of patients presenting at primary health care (PHC) facilities. The researcher observed that, despite additional clinical teaching and guidance, learners still obtained low scores in clinical assessments at completion of the programme. This study sought to determine possible reason(s) for this observation. The objectives were to explore and describe the demographic profile of learners and the correlation between different clinical assessors' scoring of learners. A purposive convenience sample consisted of learners (n = 34) and clinical assessors (n = 6). Data were collected from learners using a self-administered questionnaire and analysed using a nominal and ordinal scale measurement. Data from clinical assessors were collected using a checklist, which was statistically analysed using a software package. The variables were correlated to determine the nature of the relationship between the different clinical assessors' scores on the checklist to ensure inter-rater reliability. Findings showed that there was no significant difference in the mean of the scoring of marks between clinical assessors after correlation (p

Nomasonto B.D., Magobe; Sonya, Beukes; Ann, Müller.

264

Docking and scoring of metallo-beta-lactamases inhibitors  

DEFF Research Database (Denmark)

The performance of the AutoDock, GOLD and FlexX docking programs was evaluated for docking of dicarboxylic acid inhibitors into metallo-beta-lactamases (MBLs). GOLD provided the best overall performance, with RMSDs between experimental and docked structures of 1.8-2.6 A and a good correlation between the experimentally determined MBL-inhibitor affinities and the GOLD scores. GOLD was selected for a test including a broad spectrum of inhibitors for which experimental MBL-inhibitor binding affinities are available. This study revealed that (1) for most compound classes (dicarboxylic acids, tetrazoles, sulfonylhydrazones, and peptide-like compounds) there is a good correlation between the experimentally determined MBL-inhibitor affinities and the GOLD scores, (2) the correlation only holds within a given class, that is, scores of compounds from different classes cannot be directly compared, (3) for some compound classes (e.g. small sulphur compounds) there is no direct correlation between the experimentally determined MBL-inhibitor affinities and the GOLD scores. Using partial least squares methods, a model with R2 = 0.82 and Q2 = 0.78 for the training set was obtained based on the GOLD score and descriptors associated with binding of the IMP-1 inhibitors to the enzyme. The external Q2 for the test set is 0.73. This final model for prediction of IMP-1 MBL-inhibitor affinity handled all known classes of MBL-inhibitors, except small sulphur compounds.

Olsen, Lars; Pettersson, Ingrid

2004-01-01

265

criteria for listing review  

SCPinfonet

Criteria for Listing Review April 2010 1 Contents. 1. Why a review p4. 2. Issues to be addressed. p6. 3. The current criteria. p9. 4. The situation elsewhere. p22. 5. A detailed consideration of the issues. p36. a. Age...

266

Institutional Readiness Criteria.  

Science.gov (United States)

Presents a list of pre-conditions--or readiness criteria--that must be in place before a higher education institution can successfully implement an information technology-based redesign effort and thus see a return on its investment. Includes examples of the ways that different institutions have met these criteria. (AEF)

Twigg, Carol A.

2000-01-01

267

RANKING CHEMISTRY JOURNALS USING THE HIRSCH INDEX AND ARTICLE INFLUENCE SCORE  

Directory of Open Access Journals (Sweden)

Full Text Available This study presents the Hirsch-index, impact factor and article influence score for the ranking of Chemistry journals. The study concludes that the Hirsch-index exhibits a good correlation with the influence score. A correlation of 60 Chemistry journals is analyzed.

SILVIU JIPA

2012-12-01

268

The value of CT score in predicting surgical methods and difficulty of hepatic cystic echinococcosis  

International Nuclear Information System (INIS)

Objective: To evaluate the value of MSCT scores on surgery method selection and its difficulty estimation for hepatic cystic echinococcosis. Methods: Based on the CT features of hepatic cystic echinococcosis (HCE), an integral system including 7 items was established. Images of preoperative CT examination performed on 71 cases of hepatic cystic echinococcosis were retrospectively analyzed by the integral system and compared with actual surgical. Total 93 cystic lesions were divided into 3 groups based on CT scores: Group A suitable for total cystectomy (0 to 5 score), Group B suitable for subtotal cystectomy (6 to 10 score), and Group C suitable forendocystectomy ( ? 11 scores, or 4 score in one item), Spearman rank correlation was used to analyze the relationship between WHO classification of cystic echinococcosis and actual surgery methods, the relationship between operation mode forecasted by CT scores and actual surgery methods, the relationship between vessel scores of cyst and actual surgery methods, and that between biliary score of cyst and actual surgery methods. Fisher exact test and Chi-square test were used to evaluate the incidence of residual cavity in patients with different biliary scores. Results: Thirty nine cysts got 0 to 5 scores, 45 cysts got 6 to 10 scores and 9 cysts got more than 10 scores. Total cystectomy was performed on 30 cysts, subtotal cystectomy on 40 cysts and performed endocystectomy on 23 cysts, actually. Actual operation methods were correlated with that predicated by CT scores (r=0.741, P<0.01), and with vessels score and biliary score (r=0.587, 0.327 respectively, P<0.01). The higher the biliary score, the higher the incidence of postoperative biliary tract complications. Conclusions: Preoperative CT scoring was an easy and objective way to accurately predict the surgery methods and its difficulty for hepatic cystic echinococcosis. (authors)

269

Inter- and Intra-rater Reliabililty of a Modified Approach to Scoring the Balance Error Scoring System (BESS) in Undistracted and Distracted Conditions  

OpenAIRE

Context: We have developed a modified approach to scoring balance errors with the Balance Error Scoring System (BESS) by eliminating two of the six original error criteria. Objective: To measure the inter- and intra-rater reliability of this modified BESS approach. Because of the potential auditory distractions that may be present in a clinical setting, we also measured reliability for distracted rating conditions. Design: Cross-sectional. Setting: University sports medicine clinic. ...

Pierce, Jacob Ryan

2014-01-01

270

Plutonium storage criteria  

Energy Technology Data Exchange (ETDEWEB)

The Department of Energy has issued a technical standard for long-term (>50 years) storage and will soon issue a criteria document for interim (<20 years) storage of plutonium materials. The long-term technical standard, {open_quotes}Criteria for Safe Storage of Plutonium Metals and Oxides,{close_quotes} addresses the requirements for storing metals and oxides with greater than 50 wt % plutonium. It calls for a standardized package that meets both off-site transportation requirements, as well as remote handling requirements from future storage facilities. The interim criteria document, {open_quotes}Criteria for Interim Safe Storage of Plutonium-Bearing Solid Materials{close_quotes}, addresses requirements for storing materials with less than 50 wt% plutonium. The interim criteria document assumes the materials will be stored on existing sites, and existing facilities and equipment will be used for repackaging to improve the margin of safety.

Chung, D. [Scientech, Inc., Germantown, MD (United States); Ascanio, X. [Dept. of Energy, Germantown, MD (United States)

1996-05-01

271

Testing of the OMERACT 8 draft validation criteria for a soluble biomarker reflecting structural damage in rheumatoid arthritis: a systematic literature search on 5 candidate biomarkers  

DEFF Research Database (Denmark)

OBJECTIVE: To test the OMERACT 8 draft validation criteria for soluble biomarkers by assessing the strength of literature evidence in support of 5 candidate biomarkers. METHODS: A systematic literature search was conducted on the 5 soluble biomarkers RANKL, osteoprotegerin (OPG), matrix metalloprotease (MMP-3), urine C-telopeptide of types I and II collagen (U-CTX-I and U CTX-II), focusing on the 14 OMERACT 8 criteria. Two electronic voting exercises were conducted to address: (1) strength of evidence for each biomarker as reflecting structural damage according to each individual criterion and the importance of each individual criterion; (2) overall strength of evidence in support of each of the 5 candidate biomarkers as reflecting structural damage endpoints in rheumatoid arthritis (RA) and identification of omissions to the criteria set. RESULTS: The search identified 111 articles. The strength of evidence in support of these biomarkers reflecting structural damage was low for all biomarkers and was rated highest for U-CTX-II [score of 6.5 (numerical rating scale 0-10)]. The lowest scores for retention of specific criteria in the draft set went to criteria that refer to the importance of animal studies, correlations with other biomarkers reflecting damage, and an understanding of the metabolism of the biomarker. CONCLUSION: Evidence in support of any of the 5 tested biomarkers (MMP-3, CTX-I, CTX-II, OPG, RANKL) was inadequate to allow their substitution for radiographic endpoints in RA. Three of the criteria in the draft criteria set might not be required, but few omissions were identified.

Syversen, Silje W; Landewe, Robert

2009-01-01

272

Development of a software tool and criteria evaluation for efficient design of small interfering RNA  

International Nuclear Information System (INIS)

Research highlights: ? The developed tool predicted siRNA constructs with better thermodynamic stability and total score based on positional and other criteria. ? Off-target silencing below score 30 were observed for the best siRNA constructs for different genes. ? Immunostimulation and cytotoxicity motifs considered and penalized in the developed tool. ? Both positional and compositional criteria were observed to be important. -- Abstract: RNA interference can be used as a tool for gene silencing mediated by small interfering RNAs (siRNA). The critical step in effective and specific RNAi processing is the selection of suitable constructs. Major design criteria, i.e., Reynolds's design rules, thermodynamic stability, internal repeats, immunostimulatory motifs were emphasized and implemented in the siRNA design tool. The tool provides thermodynamic stability score, GC content and a total score based on other design criteria in the output. The viability of the tool was established with different datasets. In general, the siRNA constructs produced by the tool had better thermodynamic score and positional properties. Comparable thermodynamic scores and better total scores were observed with the existing tools. Moreover, the results generated had comparable off-target silencing effect. Criteria evaluations with additional criteria were achieved in WEKA.

273

Validation of the Rheumatoid and Arthritis Outcome Score (RAOS for the lower extremity  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Patients with inflammatory joint diseases tend due to new treatments to be more physically active; something not taken into account by currently used outcome measures. The Rheumatoid and Arthritis Outcome Score (RAOS is an adaptation of the Knee injury and Osteoarthritis Outcome Score (KOOS and evaluates functional limitations of importance to physically active people with inflammatory joint diseases and problems from the lower extremities. The aim of the study was to test the RAOS for validity, reliability and responsiveness. Methods 119 in-patients with inflammatory joint disease (51% RA admitted to multidisciplinary care, mean age 56 (±13, 73% women, mean disease duration 18 (±14 yr were consecutively enrolled. They all received the RAOS, the SF-36, the HAQ and four subscales of the AIMS2 twice during their stay for test of validity and responsiveness. Test-retest reliability of the RAOS questionnaire was calculated on 52 patients using the first or second administration and an additional mailed questionnaire. Results The RAOS met set criteria of reliability and validity. The random intraclass correlation coefficient (ICC 2,1 for the five subscales ranged from 0.76 to 0.92, indicating that individual comparisons were possible except for the subscale Sport and Recreation Function. Inter-item correlation measured by Cronbach's alpha ranged from 0.78 to 0.95. When measuring construct validity the highest correlations occurred between subscales intended to measure similar constructs. Change over time (24 (± 7 days due to multidisciplinary care was significant for all subscales (p Conclusion It is possible to adapt already existing outcome measures to assess other groups with musculoskeletal difficulties in the lower extremity. The RAOS is a reliable, valid and responsive outcome instrument for assessment of multidisciplinary care. To fully validate the RAOS further studies are needed in other populations.

Petersson Ingemar F

2003-10-01

274

Translatability scoring in drug development: eight case studies  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Translational medicine describes the transfer of basic in vitro and in vivo data into human applications. In the light of low rates of market approvals for new medical entities, better strategies to predict the risk of drug development should be used to increase output and reduce costs. Recently, a scoring system to assess the translatability of early drug projects has been proposed. Here eight drugs from different therapeutic areas have been subjected to a retrospective test-run in this system fictively located at the phase II-III transition. The scores gained here underline the importance of biomarker quality which is pivotal to decrease the risk of the project in all cases. This is particularly evident for gefitinib. The EGFR mutation status is a breakthrough biomarker to predict therapeutic success which made this compound clinically acceptable, and this is plausibly reflected by a considerable increase of the translatability score. For psychiatric and Alzheimer's drugs, and for a CETP-inhibitor, the lack of suitable biomarkers and animal models is reflected by a low translatability score, well correlating with the excessive translational risk in these areas. These case studies document the apparent utility of the scoring system, at least under retrospective conditions, as the scores correlate with the outcomes at the level of market approval. Prospective validation is still missing, but these case studies are encouraging.

Wendler Alexandra

2012-03-01

275

Fire protection design criteria  

Energy Technology Data Exchange (ETDEWEB)

This Standard provides supplemental fire protection guidance applicable to the design and construction of DOE facilities and site features (such as water distribution systems) that are also provided for fire protection. It is intended to be used in conjunction with the applicable building code, national Fire Protection Association Codes and Standards, and any other applicable DOE construction criteria. This Standard, along with other delineated criteria, constitutes the basic criteria for satisfying DOE fire and life safety objectives for the design and construction or renovation of DOE facilities.

NONE

1997-03-01

276

Early stroke risk and ABCD2 score performance in tissue- vs time-defined TIA: a multicenter study.  

OpenAIRE

OBJECTIVES: Stroke risk immediately after TIA defined by time-based criteria is high, and prognostic scores (ABCD2 and ABCD3-I) have been developed to assist management. The American Stroke Association has proposed changing the criteria for the distinction between TIA and stroke from time-based to tissue-based. Research using these definitions is lacking. In a multicenter observational cohort study, we have investigated prognosis and performance of the ABCD2 score in TIA, subcategorized as ti...

Giles, Mf; Albers, Gw; Amarenco, P.; Arsava, Em; Asimos, Aw; Ay, H.; Calvet, D.; Coutts, Sb; Cucchiara, Bl; Demchuk, Am; Johnston, Sc; Kelly, Pj; Kim, As; Labreuche, J.; Lavallee, Pc

2011-01-01

277

A novel cleansing score system for capsule endoscopy  

Directory of Open Access Journals (Sweden)

Full Text Available AIM: To suggest a new cleansing score system for small bowel preparation and to evaluate its clinical efficacy.METHODS: Twenty capsule endoscopy cases were reviewed and small bowel preparation was assessed with the new scoring system. For the assessment, two visual parameters were used: proportion of visualized mucosa and degree of obscuration. Representative frames from small bowel images were serially selected and scored at 5-min intervals. Intraclass correlation coefficient (ICC was obtained to assess the reliability of the new scoring system. For efficacy evaluation and validation, scores of our new scoring system were compared with another previously reported cleansing grading system.RESULTS: Concordance with the previous system, inter-observer agreement, and intra-patient agreement were excellent with ICC values of 0.82, 0.80, and 0.76, respectively. The intra-observer agreements at four-week intervals were also excellent. The cut-off value of adequate image quality was found to be 2.25.CONCLUSION: Our new scoring system is simple, efficient, and can be considered to be applicable in clinical practice and research.

Sung Chul Park, Bora Keum, Jong Jin Hyun, Yeon Seok Seo, Yong Sik Kim, Yoon Tae Jeen, Hoon Jai Chun, Soon Ho Um, Chang Duck Kim, Ho Sang Ryu

2010-02-01

278

Automated Versus Human Essay Scoring: A Comparative Study  

Directory of Open Access Journals (Sweden)

Full Text Available This study investigated the effects of automated essay scoring (AES system on writing improvement of Iranian L2 learners. About 60 Iranian intermediate EFL learners were selected on a Standard English proficiency test (Allen 2004. Afterwards, they were randomly assigned to two groups of 30, experimental and control group. Participants in experimental group received the AES scoring, and control group, received the human scoring. Statistical analyses of the results reveal that 1 AES tool results in significant improvement of L2 learners writing achievement, 2 Results from questionnaire show that Students ware favor about using AES tool, 3 The results from the current study support the conclusion that the AES tool does not seem to correlate well with human raters in scoring essays. Hence, the findings of this study indicate that using AES tools can help teachers ease their big teaching students to improve their writing and it can be used as an educational tool on classrooms.

Somaye Toranj

2012-04-01

279

Quantifying radioxerostomia: salivary flow rate, examiner's score, and quality of life questionnaire  

Energy Technology Data Exchange (ETDEWEB)

Background and purpose: salivary flow rates alone are not sufficient to quantify all aspects of radioxerostomia. This is a problem in studies aiming to reduce radioxerostomia. The aim of this study was to evaluate the association between objectively measured salivary flow rate and subjective xerostomia ratings by the physician (RTOG scale) or the patients (quality of life [QoL] questionnaire). Patients and methods: in a case-control study patients who underwent recall for oral cancer were screened. Inclusion criteria for this diagnostic, noninterventional study were: history of oral carcinoma, surgical and radiation therapy, time interval from start of radiation therapy > 90 days, salivary glands within the radiation field. The control group consisted of patients, who had not received radiotherapy. RTOG salivary gland score, quality of life (EORTC QLQ-C30 and H and N35), and sialometry were recorded. Results: patients with RTOG score 0 had mean salivary flow rates of 0.3 ml/min, those with RTOG 1 0.12 ml/min, RTOG 2 0.02 ml/min, and RTOG 3 < 0.01 ml/min. RTOG score 4 (total fibrosis) did not occur. Based on salivary flow rates, all patients were grouped into xerostomia < 0.2 ml/min (30 patients) and nonxerostomia (twelve patients). QoL results revealed significant differences between patients with xerostomia and nonxerostomia for physical function, dyspnea, swallowing, social eating, dry mouth, nutritional support, and a tendency to higher values for appetite loss. Conclusion: the correlation between ''subjective'' QoL parameters and salivary flow was confirmed. The different subjective aspects of radioxerostomia seem to be better differentiated by the EORTC QoL questionnaire. (orig.)

Al-Nawas, B.; Al-Nawas, K.; Kunkel, M.; Groetz, K.A. [Dept. of Oral and Maxillofacial Surgery, Hospital of the Johannes Gutenberg Univ., Mainz (Germany)

2006-06-15

280

Association between eating behavior scores and obesity in Chilean children  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Inadequate eating behavior and physical inactivity contribute to the current epidemic of childhood obesity. The aim of this study was to assess the association between eating behavior scores and childhood obesity in Chilean children. Design and methods We recruited 126 obese, 44 overweight and 124 normal-weight Chilean children (6-12 years-old; both genders according to the International Obesity Task Force (IOTF criteria. Eating behavior scores were calculated using the Child Eating Behavior Questionnaire (CEBQ. Factorial analysis in the culturally-adapted questionnaire for Chilean population was used to confirm the original eight-factor structure of CEBQ. The Cronbach's alpha statistic (>0.7 in most subscales was used to assess internal consistency. Non-parametric methods were used to assess case-control associations. Results Eating behavior scores were strongly associated with childhood obesity in Chilean children. Childhood obesity was directly associated with high scores in the subscales "enjoyment of food" (P Conclusion Our study shows a strong and graded association between specific eating behavior scores and childhood obesity in Chile.

Amador Paola

2011-10-01

281

EFR design criteria  

International Nuclear Information System (INIS)

One of the first steps to a common European design has been to harmonize the design criteria. The general goals for the plant have been separately defined by the customer utilities. EFR Associates, as the responsible designer, have devised a unique set of rules starting from the three different national frames. These cover the operating conditions, safety functions and design and construction criteria and rules. (author)

282

Meteor Stream Membership Criteria  

OpenAIRE

Criteria for the membership of individual meteors in meteor streams are discussed from the point of view of their mathematical and also physical properties. Discussion is also devoted to the motivation. It is shown that standardly used criteria (mainly D-criterion of Southworth and Hawkins, 1963) have unusual mathematical properties in the sense of a term ``distance'', between points in a phase space, and, physical motivation and realization for the purpose of obtaining thei...

Klacka, Jozef

2000-01-01

283

Classification criteria for spondyloarthropathies  

Directory of Open Access Journals (Sweden)

Full Text Available Spondyloarthropathies (SpA are a group of inflammatory arthritis which consist of ankylosing spondylitis (AS, reactive arthritis, arthritis/spondylitis associated with psoriasis (PsA, and arthritis/spondylitis associated with inflammatory bowel diseases. It is now more important than ever to diagnose and treat SpA early. New therapeutic agents including blockers of tumor necrosis factor have yielded tremendous responses not only in advanced disease but also in the early stages of the disease. Sacroiliitis on conventional radiography is the result of structural changes which may appear late in the disease process. However, magnetic resonance imaging (MRI can visualize active inflammation at sacroiliac joints and spine in recent onset disease. The modified New York criteria, the European Spondyloarthropathy Study Group criteria and the Amor criteria do not include advanced imaging techniques like MRI which is very sensitive to the early Inflammatory changes. Assessment of SpondyloArthritis international Society has defined MRI methods for the assessment of sacroiliac joints and spine, criteria for inflammatory back pain and developed new criteria for classification of axial and peripheral spondyloarthritis. These new criteria are intended to be used for patients with SpA at the very early stage of their disease. Also, classification of psoriatic arthritis study group developed criteria for the classification of PsA. The widespread use of these criteria in clinical trials will provide evidence for a better definition of early disease and recognize many patients who may further develop classical AS or PsA. These efforts will guide therapeutic trials of potent drugs like biological agents in the early stage of these diseases.

Ozgur Akgul

2011-01-01

284

Diagnostic Performance of Gadoxetic Acid-enhanced Liver MR Imaging in the Detection of HCCs and Allocation of Transplant Recipients on the Basis of the Milan Criteria and UNOS Guidelines: Correlation with Histopathologic Findings.  

Science.gov (United States)

Purpose To determine whether hepatobiliary phase ( HBP hepatobiliary phase ) imaging can improve the diagnostic performance of gadoxetic acid-enhanced liver magnetic resonance (MR) imaging in the detection of hepatocellular carcinomas ( HCC hepatocellular carcinoma s) and to investigate the accuracy of gadoxetic acid-enhanced MR imaging in the allocation of transplant recipients on the basis of the Milan criteria and United Network for Organ Sharing ( UNOS United Network for Organ Sharing ) guidelines. Materials and Methods This retrospective study had institutional review board approval; the requirement for informed consent was waived. Between June 2008 and June 2011, 63 patients who underwent liver transplantation (LT) were included. All patients underwent a gadoxetic acid-enhanced 3.0-T MR imaging examination of the liver that included HBP hepatobiliary phase images obtained 20 minutes after contrast material administration. Two abdominal radiologists independently assessed two MR imaging data sets to detect HCC hepatocellular carcinoma s: Set 1 included unenhanced and gadoxetic acid-enhanced dynamic images, and set 2 also included HBP hepatobiliary phase images. Patients were allocated into three groups: Those who did not meet the Milan criteria, those who did meet the Milan criteria with additional priority according to UNOS United Network for Organ Sharing guidelines, and those who did meet the Milan criteria without additional priority. Diagnostic performance of each data set in depicting HCC hepatocellular carcinoma s was compared by using jackknife alternative free-response receiver operating characteristics ( JAFROC jackknife alternative free-response receiver operating characteristic s). Sensitivity and accuracy of patient allocation were compared by using generalized estimating equations. Results Sixty-three HCC hepatocellular carcinoma s were found in 36 of 63 patients. Eight patients were classified as not meeting Milan criteria, 12 as meeting Milan criteria with additional priority, and 43 as meeting Milan criteria without additional priority. For the detection of HCC hepatocellular carcinoma s, reader-averaged figures of merit estimated with JAFROC jackknife alternative free-response receiver operating characteristic s were 0.761 for set 1 and 0.791 for set 2 (P HCC hepatocellular carcinoma s, particularly 1-2-cm HCC hepatocellular carcinoma s (six [20.7%] vs 13 [44.8%] of 29 [P = .008] for reader 1 and eight [27.6%] vs 12 [41.4%] of 29 [P = .041] for reader 2). Accuracy of patient allocation was 88.9% for set 1 and 92.1% for set 2 (P = .151). Conclusion Addition of HBP hepatobiliary phase images can significantly improve the diagnostic performance of gadoxetic acid-enhanced liver MR imaging in the detection of 1-2-cm HCC hepatocellular carcinoma s in liver transplantation candidates. In addition, gadoxetic acid-enhanced MR imaging showed 92.1% accuracy in patient allocation on the basis of the Milan criteria and UNOS United Network for Organ Sharing guidelines. © RSNA, 2014 Online supplemental material is available for this article. PMID:25203131

Lee, Dong Ho; Lee, Jeong Min; Baek, Jee Hyun; Shin, Cheong-Il; Han, Joon Koo; Choi, Byung Ihn

2015-01-01

285

Using SAT scores to identify students at risk in introductory physics  

Science.gov (United States)

Our previous research has shown a strong correlation between individual students’ pre-instruction scores on Lawson’s Test of Reasoning Ability and their normalized gains on the FCI. These results have been replicated by researchers at Edward Little High School in Maine, at the University of Colorado, and at the University of Central Florida. We now find that SAT scores also provide a strong correlation with FCI gains. The advantage of using SAT scores is that one does not have to administer another test; these scores are usually readily available through the registrar’s office.

Coletta, Vincent P.; Phillips, J.

2006-12-01

286

A study to validate the method based on DIMOND quality criteria for cardiac angiographic images  

International Nuclear Information System (INIS)

A method based on image quality criteria (QC) for cine-angiography was developed to measure the quality of cine-angiograms (CA). A series of 30 CA for left ventriculography (LV) and left and right coronary angiography (LCA, RCA) have been scored and 172 readings were obtained. Standard deviation of quality scores indicated the reproducibility of the method. Each part of CA was examined separately, giving scores for LV, LCA and RCA and a total score (TS), with clinical (C) and technical (T) criteria defined and examined separately. In 83% of the studies TS was >0.8 and with standard deviation from 0.02 to 0.21. In general, LV had a lower score and greater disagreement compared with RCA and LCA. Disagreement was greater in T, compared with C. In conclusion, these results indicate that QC, translated into a scoring system, yields reproducible data on the quality of cardiac images. (authors)

287

Maturidade perceptomotora e reconhecimento de palavras: estudo correlacional entre o Bender - Sistema de Pontuação Gradual e o Teste de Reconhecimento de Palavras / Perceptive-motor maturity and word recognition: a correlational study between Bender - Scoring System for Grades and Word Recognition test  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese O presente estudo objetivou investigar evidências de validade para o Bender - Sistema de Pontuação Gradual, pela relação com o Teste de Reconhecimento de Palavras, partindo da premissa de que os testes apresentariam comunalidade em certos aspectos. Além disso, a pesquisa buscou verificar se o Bender [...] é sensível para captar diferenças de média por idade. Participaram do estudo 297 crianças, sendo 153 do sexo masculino (51,5%), com idade entre 7 e 10 anos (M=9,04, DP=0,88). Cursavam do 2º ao 5º ano do ensino fundamental, em escola particular (27,3%) ou pública (72,7%) do interior do estado de São Paulo. Os instrumentos foram aplicados coletivamente, sendo que as figuras do Bender foram projetadas. Foram evidenciadas correlações significativas entre os instrumentos. Verificou-se também que o Bender mostrou-se sensível em captar as diferenças relacionadas à idade, revelando o aspecto maturacional avaliado pelo teste, assim como também revelou relação com a escolaridade. Abstract in english The aim of this study was to investigate evidence of validity of the Bender - Scoring System for Grades, by comparison with the Word Recognition Test, starting with the premise that the tests would show commonality in certain aspects. In addition, the study sought to verify whether the B-SPG is sens [...] itive to capture differences in mean for age. The study participants included 297 children, 153 being boys (51.5%) aged between 7 and 10 years (M=9.04, SD=0.88). They were in the 2nd to the 5th year of elementary schooling, at private (27.3%) and public (72.7%) schools, in the interior of State of São Paulo. The instruments were applied collectively, and the Bender - Gradual Scoring System pictures were projected. Significant correlations were observed between the instruments. Furthermore, it was found that the Bender - Gradual Scoring System was shown to be sensitive in capturing differences related to age, revealing the aspect of maturity assessed by testing, and also revealed relationship with progress in school stages.

Laura de, Carvalho; Ana Paula Porto, Noronha; Lariana Paula, Pinto; Luana, Luca.

2012-09-01

288

Relación entre el índice CHA2DS2-VASc y la presencia de trombo auricular en pacientes con fibrilación auricular en plan de cardioversión / Correlation Between CHA2DS2-VASc Score and Atrial Thrombus in Patients with Atrial Fibrillation Undergoing Cardioversion  

Scientific Electronic Library Online (English)

Full Text Available SciELO Argentina | Language: Spanish Abstract in spanish Introducción Los pacientes con fibrilación auricular representan un grupo de riesgo para el desarrollo de complicaciones tromboembólicas, con consecuencias devastadoras cuando afectan el sistema nervioso central. El rendimiento de los índices de riesgo para predecir eventos clínicos se ha evaluado e [...] n numerosas publicaciones, mientras que su relación con la presencia de trombo en la aurícula izquierda o su orejuela se ha explorado menos. Recientemente se ha propuesto la utilización del índice conocido con el acrónimo CHA2DS2-VASc para la estratificación de riesgo cardioembólico. Objetivo Evaluar la prevalencia de trombo en la aurícula izquierda y su relación con las variables del índice CHA2DS2-VASc y la función sistólica del ventrículo izquierdo en pacientes con fibrilación auricular que serán sometidos a cardioversión eléctrica. Material y métodos Se efectuó un registro prospectivo de los antecedentes clínicos de pacientes con fibrilación auricular de tiempo indeterminado o > 48 horas, a los que se les realizó un eco transesofágico previo a una cardioversión eléctrica. Se analizó la relación de las variables que conforman el índice CHA2DS2-VASc y del puntaje total para predecir trombo en el eco transesofágico. Se evaluó además un modelo que resultó de sumar al CHA2DS2-VASc un puntaje según la función sistólica del ventrículo izquierdo: normal = 0, deterioro leve = 1, moderado = 2, grave = 3. Resultados Se incluyeron 129 pacientes con edad media de 70 ± 12 años, de los cuales 21 (16%) presentaron trombo. Este hallazgo fue más prevalente en pacientes con factores de riesgo, pero alcanzó nivel de significación solo para insuficiencia cardíaca y diabetes. Se observó un incremento progresivo del riesgo de trombo en relación con el CHA2DS2-VASc (3,6 ± 1,6 con trombo vs. 2,7 ± 1 sin trombo; p = 0,024, área bajo la curva ROC = 0,65). La asociación se ve reforzada cuando se incluye la función sistólica del ventrículo izquierdo (p = 0,006, área bajo la curva ROC = 0,69). Un puntaje de CHA2DS2-VASc Abstract in english Background Patients with atrial fibrillation represent a group of risk for thromboembolic complications, with catastrophic consequences when affecting the central nervous system. The performance of risks scores to predict clinical events has been evaluated by several publications; yet, its correlati [...] on with the presence of thrombi in the left atrium or left atrial appendage has been poorly investigated. The use of the CHA2DS2-VASc score has been recently proposed for stratification of throm-boembolic risk. Objective To evaluate the prevalence of left atrial thrombus and its correlation with the components of the CHA2DS2-VASc score and with left ventricular systolic function in patients scheduled for electrical cardioversion. Methods A prospective registry of the medical history of patients with atrial fibrillation of unknown duration or lasting >48 hours, undergoing transesophageal echocardiography before scheduled electrical cardioversion was conducted. The correlation of the components of the CHA2DS2-VASc scores and of the total score with the presence of thrombi in transesophageal echocardiography was analyzed. The result of the sum of the CHA2DS2-VASc score plus a score of left ventricular systolic function (normal = 0, mild dysfunction = 1, moderate dysfunction = 2, severe dysfunction = 3) was also evaluated. Results A total of 129 patients (mean age 70±12 years) were included; 21 (16%) had thrombus. This finding was more prevalent in patients with risk factors, but was only statistically significant for heart failure and diabetes. The risk of thrombus in the LA/LAA progressively increased at higher CHA2DS2-VASc (3.6±1.6 with thrombus vs. 2.7±1 without thrombus; p = 0.024, area under the ROC curve = 0.65). This association was greater when left ventricular systolic function was included (p = 0.006, area under the ROC curve = 0.69). A CHA2DS2-VASc

Norberto G, Allende; Carlos, Rodríguez Pagani; Eduardo, Carrasco; Gerardo, Marmbio; Guillermo, López Soutric; Federico, Cintora; Fanny, Calvo; Ricardo, Pérez De La Hoz.

2013-04-01

289

Classroom Assessment Techniques: Scoring Rubrics  

Science.gov (United States)

Rubrics are an efficient and concise way to describe evaluation criteria based on the expected outcomes and performances of students. This webpage explains how rubrics can be used to allow more complex assessments without demanding too much instructor time. Students also benefit as they learn to use rubrics to determine the goals of questions and assignments.

Ebert-May, Diane; Guide, Field-Tested L.

290

To compare and contrast the various evaluation scoring systems after anterior cruciate ligament reconstruction.  

Science.gov (United States)

In a prospective study we evaluated with eight established scoring systems 56 patients who received a Leeds-Keio ligament as an anterior cruciate ligament replacement. The systems were compared based upon their total results, as well as their subjective, objective and functional criteria. It was found that the diversity of both the results and criteria within the systems made valid comparisons impossible. From this investigation it was concluded that the use of an internationally standardized evaluation system would provide the best possibility for comparison of surgical results. As a result, we recommend the IKDC Score system together with a visual analogue scale to evaluate subjective knee complaints. PMID:9006774

Labs, K; Paul, B

1997-01-01

291

Assessment of the pathological grade of astrocytic gliomas using an MRI score  

International Nuclear Information System (INIS)

To evaluate the usefulness of an MRI score for identifying tumour tissue characteristics, 41 histologically verified supratentorial astrocytic gliomas, including 13 low-grade astrocytomas 14 anaplastic astrocytomas and 14 glioblastoma multiformes, were examined with a 0.5 T superconductive MR imager. Nine MRI criteria were used: heterogeneity, cyst formation or necrosis, haemorrhage, crossing the midline, oedema or mass effect, border definition, flow void, degree and heterogeneity of contrast enhancement; Gd-enhanced T1-weighted images were obtained in 32 cases. Each of the criteria was scored and analysed statistically. (orig./MG)

292

Acceptance criteria for determining armed response force size at nuclear power plants  

International Nuclear Information System (INIS)

This guidance document contains acceptance criteria to be used in the NRC license review process. It consists of a scored worksheet and guidelines for interpreting the worksheet score that can be used in determining the adequacy of the armed response force size at a nuclear power reactor facility

293

Item Response Modeling with Sum Scores  

Science.gov (United States)

One of the distinctions between classical test theory and item response theory is that the former focuses on sum scores and their relationship to true scores, whereas the latter concerns item responses and their relationship to latent scores. Although item response theory is often viewed as the richer of the two theories, sum scores are still…

Johnson, Timothy R.

2013-01-01

294

Shwachman-Kulczycki score still useful to monitor cystic fibrosis severity  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in english INTRODUCTION: The Shwachman-Kulczycki score was the first scoring system used in cystic fibrosis to assess disease severity. Despite its subjectivity, it is still widely used. OBJECTIVE: To study correlations among forced expiratory volume in one second (FEV1), chest radiography, chest computed tomo [...] graphy, 6-minute walk test, and Shwachman-Kulczycki score in patients with cystic fibrosis and to test whether the Shwachman-Kulczycki score is still useful in monitoring the severity of the disease. METHODS: A cross-sectional prospective study was performed to analyze the correlations (Spearman). Patients with clinically stable cystic fibrosis, aged 3-21 years, were included. RESULTS: 43 patients, 19F/24M, mean age 10.5 + 4.7 years, with a median Shwachman-Kulczycki score of 70 were studied. The median Brasfield and Bhalla scores were 17 and 10, respectively. The mean Z score for the 6-minute walk test was -1.1 + 1.106 and the mean FEV1 was 59 + 26 (as percentage of predicted values). The following significant correlations versus the Shwachman-Kulczycki score were found: FEV1 (r = 0.76), 6-minute walk test (r = 0.71), chest radiography (r = 0.71) and chest computed tomography (r = -0.78). When patients were divided according to FEV1, a statistically significantly correlation with the Shwachman-Kulczycki score was found only in patients with FEV1

Fabíola, Stollar; Fabíola Villac, Adde; Maristela T., Cunha; Claudio, Leone; Joaquim C., Rodrigues.

295

Evaluation of initial diffusion-weighted image findings in acute stroke patients using a semiquantitative score  

International Nuclear Information System (INIS)

We evaluated the usefulness of rating diffusion-weighted images (DWI) using a semiquantitative score modified from the Alberta Stroke Programme Early CT Score (ASPECTS) to predict deterioration of neurological symptoms in patients with hyperacute ischemic stroke who had undergone thrombolytic therapy with recombinant tissue plasminogen activator (rt-PA). We examined 22 patients with acute stroke (14 men, 8 women, mean age 72.5 years) treated with intravenous rt-PA. All were assessed using the National Institutes of Health Stroke Scale (NIHSS) and underwent emergent magnetic resonance (MR) imaging within 3 hours and 24 hours of stroke onset. Patients were divided into a deteriorated group (16 patients), in which NIHSS scores were increased after thrombolysis, and a non-deteriorated group (6 patients). We compared the DWI score, ASPECTS, and volume of hyperintense ischemic lesion on DWI (DWI volume) of the 2 groups and examined correlations between these scores and initial NIHSS score or DWI volume. The DWI score and ASPECTS tended to be lower in the deteriorated group than the non-deteriorated group. In addition, with a cutoff value ?7, the DWI score could discriminate the deteriorated group from the non-deteriorated group with a sensitivity of 50% and specificity of 87.5%, whereas for ASPECTS, sensitivity was 50% and specificity, 81.2%. The DWI score, ASPECTS, and DWI volume had no correlation with NIHSS score but weak negative correlations with the DWI volume (P<0.e correlations with the DWI volume (P<0.01; Spearman's test). Comparing initial NIHSS score with each DWI score and DWI volume, the non-deteriorated group tended to have higher DWI scores and smaller DWI volumes than the deteriorated group, but there was no statistical difference between initial NIHSS and DWI scores. Though the DWI score was not statistically different, the threshold would be set to 6 points or above. Comparing initial DWI score with volume, patients with low DWI scores tended to show large variation in DWI volume and patients with small DWI volume showed large variation in DWI scores. There was no relation between hemorrhagic change and symptoms in either group. The semiquantitative DWI score easily evaluated extent of acute ischemic lesion on DWI and might be used to predict patient outcome after thrombolytic therapy more accurately than ASPECTS or DWI volume. (author)

296

Dual Criteria Decisions  

DEFF Research Database (Denmark)

The most popular models of decision making use a single criterion to evaluate projects or lotteries. However, decision makers may actually consider multiple criteria when evaluating projects. We consider a dual criteria model from psychology. This model integrates the familiar tradeoffs between risk and utility that economists traditionally assume, allowance for rank-dependent decision weights, and consideration of income thresholds. We examine the issues involved in full maximum likelihood estimation of the model using observed choice data. We propose a general method for integrating the multiple criteria, using the logic of mixture models, which we believe is attractive from a decision-theoretic and statistical perspective. The model is applied to observed choices from a major natural experiment involving intrinsically dynamic choices over highly skewed outcomes. The evidence points to the clear role that income thresholds play in such decision making, but does not rule out a role for tradeoffs between riskand utility or probability weighting.

Andersen, Steffen; Harrison, Glenn W.

2014-01-01

297

Pemphigus Vulgaris Activity Score and Assessment of Convergent Validity  

Directory of Open Access Journals (Sweden)

Full Text Available Pemphigus is a rare autoimmune blistering disease with different phenotypes. The evaluation of therapeutic interventions requires a reliable, valid and feasible to use measurement. However, there is no gold standard to measure the disease activity in clinical trials. In this study we aimed to introduce the pemphigus vulgaris activity score (PVAS measurement and to assess the convergent validity with the experts’ opinion of disease activity. In PVAS scoring, the distribution of pemphigus vulgaris antigen expression in different anatomical regions is taking in to account with special consideration of the healing process. PVAS is a 0-18 scale, based on the extent of mucocutaneous involvement, type of lesion and the presence of Nikolsky’s sign. The sum of the scores of total number of lesions, number of different anatomic regions involvement and Nikolsky’s sign is weighted by the type of lesion. In the present study, PVAS was assessed in 50 patients diagnosed with pemphigus vulgaris by one dermatologist. Independently, five blinded experts scored all the patients through physician’s global assessment (PGA. The convergent validity with experts’ opinion was assessed. The Spearman coefficient of correlation showed the acceptable value of 0.751 (95%CI: 0.534- 0.876. PVAS is a valid, objective and simple-to-use scoring measurement. It showed a good correlation with PGA of pemphigus disease activity in Iranian patients with pemphigus vulgaris

Cheyda Chams-Davatchi

2013-04-01

298

EuroSCORE II e a importância de um modelo local, InsCor e o futuro SP-SCORE / EuroSCORE II and the importance of a local model, InsCor and the future SP-SCORE  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese Introdução: O modelo mais utilizado para predição de mortalidade em cirurgia cardíaca foi recentemente remodelado, mas dúvidas referentes à sua metodologia e desenvolvimento têm sido relatadas. Objetivo: O objetivo deste estudo foi avaliar o desempenho do EuroSCORE II na predição de mortalidade e [...] m pacientes submetidos a cirurgia de coronária e/ou valva na instituição. Métodos: Mil pacientes, operados consecutivamente de coronária e/ou valva, entre outubro de 2008 e julho de 2009, foram analisados. O desfecho de interesse foi mortalidade intra-hospitalar. A calibração foi realizada pela correlação entre mortalidade esperada e observada por meio do teste de Hosmer Lemeshow. A discriminação foi calculada pela área abaixo da curva ROC. O desempenho do EuroSCORE II foi comparado com os modelos EuroSCORE e InsCor (modelo local). Resultados: Na calibração, o teste de Hosmer Lemeshow foi inadequado para o EuroSCORE II (P=0,0003) e bom para os modelos EuroSCORE (P=0,593) e InsCor (P=0,184). No entanto, na discriminação, a área abaixo da curva ROC para o EuroSCORE II foi de 0,81 [IC 95% (0,76-0,85), P Abstract in english Introduction: The most widely used model for predicting mortality in cardiac surgery was recently remodeled, but the doubts regarding its methodology and development have been reported. Objective: The aim of this study was to assess the performance of the EuroSCORE II to predict mortality in pati [...] ents undergoing coronary artery bypass grafts or valve surgery at our institution. Methods: One thousand consecutive patients operated on coronary artery bypass grafts or valve surgery, between October 2008 and July 2009, were analyzed. The outcome of interest was in-hospital mortality. Calibration was performed by correlation between observed and expected mortality by Hosmer Lemeshow. Discrimination was calculated by the area under the ROC curve. The performance of the EuroSCORE II was compared with the EuroSCORE and InsCor (local model). Results: In calibration, the Hosmer Lemeshow test was inappropriate for the EuroSCORE II (P=0.0003) and good for the EuroSCORE (P=0.593) and InsCor (P=0.184). However, the discrimination, the area under the ROC curve for EuroSCORE II was 0.81 [95% CI (0.76 to 0.85), P

Luiz Augusto Ferreira, Lisboa; Omar Asdrubal Vilca, Mejia; Luiz Felipe Pinho, Moreira; Luís Alberto Oliveira, Dallan; Pablo Maria Alberto, Pomerantzeff; Luís Roberto Palma, Dallan; Maria Raquel B., Massoti; Fabio B., Jatene.

2014-03-01

299

Flame temperature criteria tests  

International Nuclear Information System (INIS)

Since the Lewis-Karlovitz flame temperature criteria had been based on data obtained from hydrogen flammability tests using hydrogen-air mixtures at room temperature and atmospheric pressure, a test program was conducted at Fenwal Incorporated to evaluate its applicability to a post-accident containment atmosphere at elevated temperature and pressure. Another objective of this test program was to obtain laminar burning velocities under post-accident containment atmospheric conditions. These velocities are needed for estimating the hydrogen burn time in containments. This paper presents the results obtained from this test program, which are then used to validate the Lewis-Karlovitz flame temperature criteria

300

Developing seismic design criteria  

International Nuclear Information System (INIS)

Considerations in developing seismic design criteria are presented. A diagram is provided on the relationship of the design process and design criteria components. Empirical methods have always played a major role in design of underground openings. However, licensing procedures have served to increase the rigors of seismic analysis, but the state of quantitative methods is not yet as sophisticated for subsurface structures as it is for surface structures. A table of potential damage modes during the operational phase and during the decommissioned phase is presented

301

Score Calibration in Face Recognition  

OpenAIRE

This paper presents an evaluation of verification and calibration performance of a face recognition system based on inter-session variability modeling. As an extension to the calibration through linear transformation of scores, categorical calibration is introduced as a way to include additional information of images to calibration. The cost of likelihood ratio, which is a well-known measure in the speaker recognition field, is used as a calibration performance metric. Evaluated on the challe...

I Mantasari, Miranti; Gu?nther, Manuel; Wallace, Roy; Saedi, Rahim; Marcel, Se?bastien; Leeuwen, David

2014-01-01

302

The Bandim tuberculosis score : Reliability and comparison with the Karnofsky performance score  

DEFF Research Database (Denmark)

Background: This study was carried out in Guinea-Bissau's capital Bissau among inpatients and outpatients attending for tuberculosis (TB) treatment within the study area of the Bandim Health Project, a Health and Demographic Surveillance Site. Our aim was to assess the variability between 2 physicians in performing the Bandim tuberculosis score (TBscore), a clinical severity score for pulmonary TB (PTB), and to compare it to the Karnofsky performance score (KPS). Method: From December 2008 to July 2009 we assessed the TBscore and the KPS of 100 PTB patients at inclusion in the TB cohort and/or at 1 or more follow-up visits; 61 baseline and 130 follow-up double assessments were obtained. Results: The inter-observer variability of the TBscore (5 symptoms and 6 clinical findings) varied from slight to almost perfect agreement. For the TBscore, all 3 severity classes (SC I-III) were observed, while the KPS only yielded 2 of its 3 possible classes. The grading of PTB patients into severity classes showed moderate agreement for both the TBscore (?(w) = 0.52, 95% confidence interval 0.46-0.56) and the KPS (?(w) = 0.49, 95% confidence interval 0.33-0.65). The intra-class correlation coefficient (ICC) was larger for the TBscore than for the KPS (0.822 vs 0.632). Conclusions: The Bandim TBscore had an acceptable inter-observer variability, seemed to be more disease-related, and performed better than the KPS.

Rudolf, Frauke; Joaquim, Luis Carlos

2013-01-01

303

Cross-Cultural Adaptation of Developmental Criteria for Young Children: A Preliminary Psychometric Study  

Directory of Open Access Journals (Sweden)

Full Text Available Authentic assessment approach applies naturalistic observation method to gather and analyse data about children’s development that are socio-culturally appropriate to plan for individual teaching and learning needs. This article discusses the process of adapting an authentic developmental instrument for children of 3-6 years old. The instrument consists of 217 criteria of development for children between the ages of 36-72 months; grouped under six domains, which are fine motor, gross motor, adaptive, cognitive, socio-communication, and social. It is a criterion measurement tool, which was developed for the American context. This instrument needed to be adapted into the Malay socio-cultural context before it could be applied in local setting. The adaptation process involved directly translating the items; investigating the items/criteria’s score format; examining the items by a panel of experts; observing the real setting to investigate the score patterns and calculating observer agreement index. 103 children from the Malay ethnic group aged between 36-72 months, six field experts, and twelve observers were involved as participants. The researcher and an editor translated all the criteria for development; novice observers carried out a pilot study to test the suitability of score format; six children’s specialists examined the translated criteria; and lastly, the researcher observed activities in the preschool setting to score the criteria in naturalistic manner. The translated criteria, checklists; and developmental scores were analysed through visual and descriptive statistics. Content analyses showed that most of the developmental criteria were suitable to be applied in the research context. However, there are a few criteria considered as not appropriate and scores between observers indicated low agreement on how they interpreted the criteria.

Faridah Yunus

2014-12-01

304

Comparison of subjective and objective intradermal allergy test scoring methods in dogs with atopic dermatitis.  

Science.gov (United States)

An intradermal allergy test (IDT) is an important diagnostic tool for identifying offending allergens in canine atopic dermatitis. No standardized method of scoring an IDT has been described. The purpose of this study was to determine whether there is a correlation between a conventional, subjective IDT scoring method based on perceived wheal diameter, erythema, and turgor (0-4+) and an objective scoring method based on measuring wheal diameter alone. Thirty-four atopic dogs were skin tested with 68 different allergens. All skin tests were performed according to standard procedures, and any IDT score ?2+ was considered clinically significant. When the subjective IDT scores were compared with the objective IDT scores in all dogs, there was a moderate level of correlation overall (r=0.457; P IDT. PMID:22058346

Hubbard, Tomeshia L; White, Patricia D

2011-01-01

305

Scoring radiologic characteristics to predict proliferative potential in meningiomas  

International Nuclear Information System (INIS)

We investigated the feasibility of using radiologic characteristics to predict the proliferative potential in meningiomas. Our statistical analysis revealed that the presence of peritumoral edema, an ambiguous brain-tumor border, and irregular tumor shape were significantly correlated with a higher MIB-1 staining index (SI) value. We developed the following scoring system for specific features in each tumor: peritumoral edema (tumor with edema=1, tumor without edema=0); brain-tumor border (tumor with any ambiguous border=1, tumor circumscribed by a distinct rim=0); and tumor shape (tumor with irregular shape=1, tumor with smooth shape=0). Using Spearman's correlation coefficient analysis, we found a significant correlation (P<0.005) between total score calculated for each patient and SI value. Our findings suggest that the proliferative potential of meningiomas can be predicted using a less invasive preoperative examination focusing on the presence of peritumoral edema, ambiguous brain-tumor border, and irregular tumor shape. (author)

306

Developing a magnetic resonance imaging scoring system for peripheral psoriatic arthritis.  

DEFF Research Database (Denmark)

We describe the first steps in developing an OMERACT magnetic resonance imaging (MRI) scoring system for peripheral psoriatic arthritis (PsA). A preexisting MRI dataset (finger joints) from 10 patients with PsA was scored by 4 readers for bone erosion, bone edema, synovitis, tendinopathy, and extracapsular features of inflammation (including enthesitis) according to specified criteria. Scoring reliability between readers was moderate to high for bone edema and erosion, but lower for soft tissue inflammation. Measures to improve reliability for future exercises will include reviewing definitions of pathological features and prior reader calibration.

McQueen, Fiona; Lassere, Marissa

2007-01-01

307

Optimized patterns for digital image correlation  

OpenAIRE

This work presents theoretical background on a novel class of strain sensor patterns. A combination of morphological image processing and Fourier analysis is used to characterize gray-scale images, according to specific criteria, and to synthesize patterns that score particularly well on these criteria. The criteria are designed to evaluate, with a single digital image of a pattern, the suitability of a series of images of that pattern for full-field displacement measurements by digital image...

Bossuyt, Sven

2013-01-01

308

Credit Scoring Model Hybridizing Artificial Intelligence with Logistic Regression  

Directory of Open Access Journals (Sweden)

Full Text Available Today the most commonly used techniques for credit scoring are artificial intelligence and statistics. In this paper, we started a new way to use these two kinds of models. Through logistic regression filters the variables with a high degree of correlation, artificial intelligence models reduce complexity and accelerate convergence, while these models hybridizing logistic regression have better explanations in statistically significance, thus improve the effect of artificial intelligence models. With experiments on German data set, we find an interesting phenomenon defined as ‘Dimensional interference’ with support vector machine and from cross validation it can be seen that the new method gives a lot of help with credit scoring.

Han Lu

2013-01-01

309

Residual radioactivity criteria  

International Nuclear Information System (INIS)

This paper provides an overview of current and future decommissioning standards applicable in the United States. The standards promulgated by both the US Department of Energy (DOE) and the US Nuclear Regulatory Commission (NRC), as well as standards proposed by the American National Standards Institute, are presented. A summary is presented of the recent NRC actions to produce revised residual radioactivity criteria

310

The internal consistency of medical students? scores in their physiopathology and clinical courses  

Directory of Open Access Journals (Sweden)

Full Text Available Background: To quantify the internal consistency of medical students? scores. Aim: We assessed the associations between medical students? scores in physiopathology and clinical courses and compared these scores with their scores in their comprehensive exams. Settings and Design: We collected medical students? scores in their courses and also in their comprehensive exam in six consecutive years. Materials and Methods: We assessed the associations between students? scores and their personal characteristics, and the consistency between theoretical and practical courses. Statistical Analysis: We used Pearson correlation coefficient and linear regression. In addition, we computed difficulty and discrimination indices of students? scores in their courses by comparing these scores with comprehensive clinical exam (CCE. Results: Generally, females and younger students were more successful. CCE were predicted by students? scores and their characteristics relatively accurate (the adjusted R2 of the model was 0.59. Students? scores in the pathology and in thesis had the maximum and minimum discrimination indices, while the difficulties of these two courses were in reverse order. The strongest association was observed between theoretical and practical scores in internal medicine while the associations between theoretical and practical scores in the other courses were not strong although all of them were statistically significant. Conclusions: Using this approach to explore the students? score, might highlight the weak points of the current educational system. For example we found that the students? score in thesis had the minimum accuracy; although students obtained very high score in this course. Hence, for better comparison of the accuracy students? scores in colleges around the world, we recommend similar quantitative approach

Esmaeili Aryan

2008-07-01

311

Relation of computer esthesiometry and symptom scores in diagnostics of diabetic polyneuropathy  

Directory of Open Access Journals (Sweden)

Full Text Available The purpose of our research was to define the most important diagnostic criteria in early diagnosis of distal polyneuropathy in diabetic patients. Participants included 175 patients with diabetes mellitus types 1 and 2 (male-to-female ratio 89:86, mean (±SD age 42.02±15.27 years with risk diabetic polyneuropathy. Research included Total Symptom Score, Neuropathy Symptom Score, Neuropathy Impairment Score, Visual Analog Score, standard somatic and neurologic status were evaluated in all patients at the beginning of the study. Vibration sensitivity investigated on lower extremities by means of the computer diagnostic equipment " Vibrotester - MBN" (Moscow, Russian Federation in a wide range of vibration frequencies (8, 16, 32, 63, 125, 250, 500 Hz. Statistical data processing was using Statistica v.8.0 (StatSoft, USA. Diabetic polyneuropathy was diagnosed in 166 (94.7% patients with diabetes mellitus. The most sensitive methods were computer esthesiometry method, Neuropathy Impairment Score, and their combination.

Olga Darsavelidze

2010-12-01

312

Pretreatment Beck Depression Inventory score is an important predictor for Post-treatment score in infertile patients: a before-after study  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background The experience of infertility can be extremely stressful. Some of the risk factors for depression in infertility are being female, repeated unsuccessful treatment cycles or a 2 to 3 year history of infertility, low socioeconomic status, foreign nationality, lack of partner support, life events and previous depression. In this study, we analyzed the Beck Depression Inventory score at the beginning and the end of infertility treatment, to determine which factors may influence the BDI score after treatment of infertility. Methods In a before-after study, in a university-affiliated teaching hospital, 251 women who had been visited for assisted reproductive technology infertility treatment participated in the study. BDI score was assessed before and after treatment of infertility. Results The mean BDI score rose after unsuccessful treatment and dropped after successful treatment. Those with lower education levels had a higher BDI score before treatment. BDI score after treatment was positively correlated with pretreatment BDI scoreand duration of infertility. Conclusion BDI score after treatment was strongly connected to the BDI score before treatment, the result of therapy and to the duration of infertility. The influence of duration of infertility on BDI score after treatment of infertility is weak. So a simple method to screen patients at risk of depression after infertility treatment is determining pretreatment BDI score and predicting the result of infertility treatment by other risk factors.

Ramezanzadeh Fatemeh

2005-05-01

313

Construction and evaluation of a multidimensional score to assess varicose vein severity - the Homburg Varicose Vein Severity Score (HVVSS).  

Science.gov (United States)

To evaluate a novel score (HVVSS) for varicose vein patients combining subjective symptoms, clinical findings and functional data of venous insufficiency. 91 patients (118 legs) with primary varicose veins of the great, small or accessory anterior saphenous vein were treated with conventional surgery. HVVSS was assessed pre- and 3 months postoperatively. The data were compared with established clinical and disease-related life quality scores (VCSS, AVVQ, CIVIQ). Test responsiveness, validity and reliability were determined using correlations with CEAP stage and venous refilling time as hemodynamic parameter, and inter-observer variability was assessed. All scores were highly responsive to varicose vein surgery (p<0.001). HVVSS(0-100) decreased from 34.1 ± 13.0 to 9.6 ± 6.9 postoperatively. The relative score change of HVVSS was superior to VCSS (69.5% vs. 58.8%, p=0.005). HVVSS revealed highly significant correlations with the clinical CEAP stage and was exclusively able to differentiate mild from severe disease as defined by venous refilling time (p=0.009). Inter-observer reliability of HVVSS was confirmed by correlation coefficients of 0.977 and 0.950 pre- and postoperatively (p<0.001). HVVSS is a suitable and reliable tool to assess disease severity in varicose vein patients and to quantify therapeutic effects of varicose vein treatment. PMID:21680286

Rass, Knuth; Daschzeren, Mönchzezeg; Gräber, Stefan; Vogt, Thomas; Tilgen, Wolfgang; Frings, Norbert

2011-01-01

314

Evaluation of association between obstructive sleep apnea and coronary risk scores predicted by tomographic coronary calcium scoring in asymptomatic patients  

Directory of Open Access Journals (Sweden)

Full Text Available Objective: This cross-sectional observational study is designed to evaluate direct effects of obstructive sleep apnea syndrome (OSA on presence and extent of coronary atherosclerosis by using tomographic coronary calcification scoring on a population asymptomatic for coronary artery disease.Methods: Ninety-seven consecutive patients (49.17±0.86 years who were evaluated with sleep study for the suspicion of obstructive sleep apnea syndrome underwent tomographic coronary calcium scoring test. Cardiovascular risk factors, current medications and sleep study recordings of all patients were recorded. Patients were classified into 4 groups according to the apnea-hypopnea index (AHI. Linear and logistic regression analyses were used for assessment of association between variables.Results: Coronary risk scores of patients, assessed by tomographic coronary calcium scoring, were observed to increase linearly from simple snoring group to severe OSA groups (p=0.046. When patients were classified according to their gender, AHI and parameters reflecting severity of OSA-related hypoxia were found to correlate significantly with coronary risk scores of women but not with scores of men. Linear regression analysis revealed age as the only independent associated variable with cardiovascular risk scores assessed by tomographic coronary calcification scoring (Beta coefficient: 0.27, 95% CI 0.007-0.087, p=0.018. Binary logistic regression analysis also revealed age as the only variable which independently predicted the presence of coronary calcification (OR:1.11, 95% CI 1.039-1.188, p=0.002.Conclusion: These results suggest that presence of OSA may contribute to coronary artery disease risk of patients in association with its severity; however, association between OSA and subclinical atherosclerosis seems to be primarily dependent on age.

Alper Kepez

2011-08-01

315

Correlation between HRCT and pulmonary functional tests in cystic fibrosis  

International Nuclear Information System (INIS)

Purpose. To compare the HRCT score by Oikonottlou and air trapping in expiratory scans with pulmonary functional tests and evaluate which radiological criteria are more useful to predict clinical impairment. Materials and methods. From January to September 2003, pulmonary HRCT study was performed in 37 patients (23 males), aged between 7 and 41 years, with cystic fibrosis. In the same day of CT examination they also received a complete functional evaluation. HRCT studies were evaluated by three radiologists blinded to the clinical data and were correlated with the lung function tests. Results. We obtained a high correlation (p=0.01) for two of the HRCT signs: extent of mucus plugging and mosaic perfusion pattern and all function tests. Discussion. Previous studies have demonstrated good correlation between lung function tests, in particular with FEV1 and HRCT signs. Our study differed from previous ones in that we analysed the correlation between lung function tests and with both single and combined CT criteria. Conclusion. Our results suggest that a simplified HRCT store could be useful to evaluate patients with cystic fibrosis

316

A novel 8-joint ultrasound score is useful in daily practice for rheumatoid arthritis.  

Science.gov (United States)

Objectives. To investigate the optimal number and combination of joints to be assessed by power Doppler ultrasonography (PDUS) in daily practice for rheumatoid arthritis (RA). Methods. PDUS were performed in 24 joints, including all proximal interphalangeal, metacarpophalangeal (MCP), and bilateral wrist and knee joints in 234 patients with RA. PD signals were scored semiquantitatively from 0 to 3 in each joint, and total PD score-24 was calculated by summing them up as comprehensive assessment. Results. Positive PD signals were more frequently found in bilateral wrist, knee, and the second and third MCP joints than the other joints. The individual PD scores of these 8 joints also showed higher correlation coefficients with total PD score-24 (rs ? 0.4). Among the sum PD scores of various selected joint combinations, the score of the combination of 8 joints (total PD score-8), including bilateral second and third MCP, wrist, and knee joints, showed the highest sensitivity and negative predictive value (98.1% and 96.2%, respectively). Total PD score-8 showed high correlation with the total PD score-24 (rs = 0.97, p < 0.01). Conclusions. Total PD score-8 is simple and efficient enough for monitoring disease activity and judging imaging remission of RA in daily practice. PMID:25401228

Yoshimi, Ryusuke; Ihata, Atsushi; Kunishita, Yosuke; Kishimoto, Daiga; Kamiyama, Reikou; Minegishi, Kaoru; Hama, Maasa; Kirino, Yohei; Asami, Yukiko; Ohno, Shigeru; Ueda, Atsuhisa; Takeno, Mitsuhiro; Ishigatsubo, Yoshiaki

2014-11-17

317

Bias Adjusted Precipitation Threat Scores  

Directory of Open Access Journals (Sweden)

Full Text Available Among the wide variety of performance measures available for the assessment of skill of deterministic precipitation forecasts, the equitable threat score (ETS might well be the one used most frequently. It is typically used in conjunction with the bias score. However, apart from its mathematical definition the meaning of the ETS is not clear. It has been pointed out (Mason, 1989; Hamill, 1999 that forecasts with a larger bias tend to have a higher ETS. Even so, the present author has not seen this having been accounted for in any of numerous papers that in recent years have used the ETS along with bias "as a measure of forecast accuracy".

A method to adjust the threat score (TS or the ETS so as to arrive at their values that correspond to unit bias in order to show the model's or forecaster's accuracy in extit{placing} precipitation has been proposed earlier by the present author (Mesinger and Brill, the so-called dH/dF method. A serious deficiency however has since been noted with the dH/dF method in that the hypothetical function that it arrives at to interpolate or extrapolate the observed value of hits to unit bias can have values of hits greater than forecast when the forecast area tends to zero. Another method is proposed here based on the assumption that the increase in hits per unit increase in false alarms is proportional to the yet unhit area. This new method removes the deficiency of the dH/dF method. Examples of its performance for 12 months of forecasts by three NCEP operational models are given.

F. Mesinger

2008-04-01

318

Automatic scoring of the severity of psoriasis scaling  

DEFF Research Database (Denmark)

In this work, a combined statistical and image analysis method to automatically evaluate the severity of scaling in psoriasis lesions is proposed. The method separates the different regions of the disease in the image and scores the degree of scaling based on the properties of these areas. The proposed method provides a solution to the lack of suitable methods to assess the lesion and to evaluate changes during the treatment. An experiment over a collection of psoriasis images is conducted to test the performance of the method. Results show that the obtained scores are highly correlated with scores made by doctors. This and the fact that the obtained measures are continuous indicate the proposed method is a suitable tool to evaluate the lesion and to track the evolution of dermatological diseases.

Gomez, David Delgado; ErsbØll, Bjarne Kjær

2004-01-01

319

Undervoltage Breakdown Threshold Criteria  

Science.gov (United States)

Undervoltage breakdown, the process by which a pulse of electrons induces a discharge gap to break down when it is near but has not achieved its self-breakdown conditions, is discussed. Specifically, threshold criteria that determine the number of electrons required to induce breakdown both to glow and arc discharges are presented. Numerical and theoretical predictions of these criteria are compared with experimental results. Undervoltage breakdown is the phenomenon that governs discharge initiation in gas-fed pulsed plasma thrusters, the device of primary interest to the authors. The phenomenon is also relevant to several other applications including psuedospark switches and other command-triggering devices as well as gas avalanche particle detectors.

Cooley, James; Choueiri, Edgar

2006-10-01

320

Human Systems Design Criteria  

DEFF Research Database (Denmark)

This paper deals with the problem of designing more humanised computer systems. This problem can be formally described as the need for defining human design criteria, which — if used in the design process - will secure that the systems designed get the relevant qualities. That is not only the necessary functional qualities but also the needed human qualities. The author's main argument is, that the design process should be a dialectical synthesis of the two points of view: Man as a System Component, and System as Man's Environment. Based on a man's presentation of the state of the art a set of design criteria is suggested and their relevance discussed. The point is to focus on the operator rather than on the computer. The crucial question is not to program the computer to work on its own conditions, but to “program” the operator to function on human conditions.

Rasmussen, Jens

1982-01-01

321

Correlação entre Inventário de Depressão de Beck e cortisol urinário em diabéticos tipo 2 / Correlation between urine cortisol and scores on the Beck Depression inventory in patients with type 2 diabetes / Correlación entre el inventario de Depresión de Beck y el cortisol urinario en diabeticos tipo 2  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese OBJETIVO: Verificar a correlação entre o cortisol urinário e o Inventário de Depressão de Beck em diabéticos do tipo 2. MÉTODOS: O cortisol urinário foi avaliado em uma amostra composta por 40 pacientes da Liga de Controle de Diabetes da Disciplina de Endocrinologia do Hospital das Clínicas da Facul [...] dade de Medicina da Universidade de São Paulo e para a avaliação dos sintomas de depressão foi aplicado o Inventário de Depressão de Beck. RESULTADOS: Alta confiabilidade para o Inventário de Depressão de Beck(Alfa de Cronbach=0,920)e correlação significativa foi observada entre cortisol urinário e Inventário de Depressão de Beck(Spearman,r=0.523,p Abstract in spanish OBJETIVO: Verificar la correlación entre el cortisol urinario y el Inventario de Depresión de Beck en diabéticos del tipo 2. MÉTODOS: El cortisol urinario fue evaluado en una muestra compuesta por 40 pacientes de la Liga de Control de Diabetes de la Disciplina de Endocrinología del Hospital de las C [...] línicas de la Facultad de Medicina de la Universidad de Sao Paulo y para la evaluación de los síntomas de depresión fue aplicado el Inventario de Depresión de Beck. RESULTADOS: Alta confiabilidad para el Inventario de Depresión de Beck(Alfa de Cronbach=0,920) y correlación significativa observada entre el cortisol urinario e Inventario de Depresión de Beck (Spearman,r=0.523,p Abstract in english OBJECTIVE: To determine the relationship between urinary cortisol and scores on the Beck Depression Inventory in type 2 diabetics. METHODS: The sample consisted of 40 patients with type 2 diabetes from the diabetes control league of the discipline of endocrinology of the HCFM-USP. Measures consisted [...] of urinary cortisol and depression symptoms using the Beck Depression Inventory. RESULTS: The Beck Depression Inventory had a Cronbach's alpha of 0.92. There was a statistically significant correlation between urinary cortisol and scores on the Beck Depression Inventory (Spearman r = 0.52, p

Alexandra Bulgarelli do, Nascimento; Eliane Corrêa, Chaves; Sônia Aurora Alves, Grossi; Simão Augusto, Lottenberg.

322

Correlação entre Inventário de Depressão de Beck e cortisol urinário em diabéticos tipo 2 Correlación entre el inventario de Depresión de Beck y el cortisol urinario en diabeticos tipo 2 Correlation between urine cortisol and scores on the Beck Depression inventory in patients with type 2 diabetes  

Directory of Open Access Journals (Sweden)

Full Text Available OBJETIVO: Verificar a correlação entre o cortisol urinário e o Inventário de Depressão de Beck em diabéticos do tipo 2. MÉTODOS: O cortisol urinário foi avaliado em uma amostra composta por 40 pacientes da Liga de Controle de Diabetes da Disciplina de Endocrinologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo e para a avaliação dos sintomas de depressão foi aplicado o Inventário de Depressão de Beck. RESULTADOS: Alta confiabilidade para o Inventário de Depressão de Beck(Alfa de Cronbach=0,920e correlação significativa foi observada entre cortisol urinário e Inventário de Depressão de Beck(Spearman,r=0.523,pOBJETIVO: Verificar la correlación entre el cortisol urinario y el Inventario de Depresión de Beck en diabéticos del tipo 2. MÉTODOS: El cortisol urinario fue evaluado en una muestra compuesta por 40 pacientes de la Liga de Control de Diabetes de la Disciplina de Endocrinología del Hospital de las Clínicas de la Facultad de Medicina de la Universidad de Sao Paulo y para la evaluación de los síntomas de depresión fue aplicado el Inventario de Depresión de Beck. RESULTADOS: Alta confiabilidad para el Inventario de Depresión de Beck(Alfa de Cronbach=0,920 y correlación significativa observada entre el cortisol urinario e Inventario de Depresión de Beck (Spearman,r=0.523,pOBJECTIVE: To determine the relationship between urinary cortisol and scores on the Beck Depression Inventory in type 2 diabetics. METHODS: The sample consisted of 40 patients with type 2 diabetes from the diabetes control league of the discipline of endocrinology of the HCFM-USP. Measures consisted of urinary cortisol and depression symptoms using the Beck Depression Inventory. RESULTS: The Beck Depression Inventory had a Cronbach's alpha of 0.92. There was a statistically significant correlation between urinary cortisol and scores on the Beck Depression Inventory (Spearman r = 0.52, p < .001. CONCLUSIONS: The Beck Depression Inventory was found to be a reliable indicator of depressive symptoms in patients with type 2 diabetes. Urine cortisol is associated with the presence of depressive symptoms.

Alexandra Bulgarelli do Nascimento

2009-01-01

323

Validation of Geriatric Depression Scale--5 Scores among Sedentary Older Adults  

Science.gov (United States)

This study examined the validity of Geriatric Depression Scale--5 (GDS-5) scores among older sedentary adults based on its structural properties and relationship with external criteria. Participants from two samples (Ns = 185 and 93; M ages = 66 and 67 years) completed baseline assessments as part of randomized controlled exercise trials.…

Marquez, David X.; McAuley, Edward; Motl, Robert W.; Elavsky, Steriani; Konopack, James F.; Jerome, Gerald J.; Kramer, Arthur F.

2006-01-01

324

Criteria of amorphous solidification  

OpenAIRE

A different perspective on the long-standing problem of amorphous solidification is offered, based on an alternative definition of a solid as a porous medium. General, model-free results are obtained concerning the growing dynamic length accompanying solidification and its relation to the growing relaxation time. Criteria are derived for the dynamic length to diverge and for its divergence to entail the arrest of particle motion.

Diamant, Haim

2014-01-01

325

Does Work Environment Affect Faculty Health Scores?  

Directory of Open Access Journals (Sweden)

Full Text Available This study investigates the relationship between self-reported health scores with work environment and various components of a women faculty score at a Research 1 University in the Midwest USA. The study examines the differences between male and female faculty responses in the various components making up the women faculty score and also gender differences in self-reported health scores and work environment scores. Differences between STEM and Non-STEM faculty are examined. A significant positive relationship is found between self-reported health scores and work environment controlling for gender. The study finds that the overall university work environment has a stronger relationship to faculty health than adequate gender ratio, women climate, and women leadership, even for women faculty. No significant differences in responses are found between STEM and Non-STEM faculty for women climate, women leadership, health scores, and work environment scores. Significant differences are found only in adequate gender ratio.

Rhonda C. Magel

2013-09-01

326

Scoring system in cirrhotics due to viral hepatitis  

International Nuclear Information System (INIS)

Objective: To determine the association of serum cholesterol levels with Child-Pugh class in patients with decompensated chronic liver disease due to viral hepatitis. Methodology: Consecutive patients attending outpatient department or admitted in medical unit III were eligible if they had a diagnosis of cirrhosis secondary to viral hepatitis. Patients were excluded if alcoholic, diabetic, hypertensive, or with non-alcoholic fatty liver disease, autoimmune, metabolic, cardiovascular, cerebrovascular or kidney diseases and recent use of lipid-regulating drugs. Serum lipid profile was determined after an overnight fast of 12 hours. On the basis of serum total cholesterol, patients were divided into four groups; Group I with serum total cholesterol = 100 mg/dl, Group II with level of 101-150 mg/dl, Group III with level of 151-200 mg/dl and Group IV with serum total cholesterol level of > 200 mg/dl. Hepatic dysfunction was categorized according to Child-Pugh scoring system. Chi-square and Spearman's correlation testing with p < 0.05 was accepted as significant. Results: One hundred and fourteen patients met the inclusion criteria with a mean age of 40.32 +- 13.59 years. Among these 32 were females (28.1%) while 82 were males (71.9%). According to Child-Pugh class; 34 patients (29.8%) presented with Child-Pugh class A, 34 (29.8%) in class B and 46 (40.4%) were in class C. Serum cholesterol (total) and triglycerides had significant association with Child-Pugh class (p = 0.0association with Child-Pugh class (p = 0.0001 and p = 0.004 respectively) suggesting that as severity of liver dysfunction increases; serum cholesterol and triglycerides levels decrease. Results also revealed that males were significantly more hypocholesterolemic than females (p = 0.006). Conclusion: Hypocholesterolemia is a common finding in decompensated chronic liver disease and has got significant association with Child-Pugh class. It may increase the reliability of Child-Pugh classification in assessment of severity and prognosis in chronic liver disease patients. (author)

327

Proposal of a CT scoring system of the paranasal sinuses in diagnosing cystic fibrosis  

International Nuclear Information System (INIS)

The purpose of this study was to develop a paranasal sinus CT scoring system that could be used as a diagnostic tool to discriminate cystic fibrosis (CF) patients from control patients examined for sinonasal disease. The model should include as few and easily applicable criteria as possible, supported by statistical analyses and clinical judgement. We used data from 116 CF and 136 control patients. The CF patients were grouped according to the number of confirmed CF mutations: genetically verified (CF-2), or based on sweat testing and clinical findings alone (CF-1, CF-0). Nine paranasal sinus CT criteria, including development, pneumatisation variants and inflammatory patterns, were evaluated. The final model included three criteria: (a) frontal and (b) sphenoid sinus development, and (c) absence of three pneumatisation variants. This model discriminated CF-2 from controls with overlap of summed scores in only 8 of 206 patients. When this model was applied in the CF-1 and CF-0 groups, two populations seemed to exist. A larger group with summed scores overlapping that of the CF-2 group and a smaller group with summed scores overlapping that of the control group. We conclude that this CT scoring system may support, as well as exclude, a CF diagnosis in cases of diagnostic uncertainty. (orig.)

328

A novel scoring system for evaluation of results of autologous transplantation methods in vitiligo  

Directory of Open Access Journals (Sweden)

Full Text Available Autologous transplantation of melanocyte/melanocytes bearing epidermis for vitiligo can be done by mini-punch grafting (MPG, suction blister epidermal grafting (SBEG, thin split -thickness skin grafting (TSTG, transplantation of basal cell layer enriched suspension and cultured epithelial/melanocyte transplantation. To date no comparative study of these transplantation procedures has been published. Comparison of different studies carried out at different centers may be difficult in the absence of uniform evaluation criteria. In most of the published studies, the results were evaluated in terms of extent of pigmentation. Complictions and color match were evaluated separately. This approach, however, may not give a fair idea about the results. We have developed a scoring system with holistic approach considering the extent of pigmentation, color match and the complications of both the donor and the recipient areas, all taken together. In the scoring system, the score for individual criteria was multiplied with a factor, the value of which was decided on the basis of relative importance of each criteria. The use of this scoring system is exemplified in twelve patients who underwent TSTG, SBEG and MPG. In the scoring system the results were judged as excellent and fair in 3 patients each, as good in 4 patients and as poor in 2 patients.

Gupta Somesh

2002-01-01

329

The HEART score for chest pain patients  

OpenAIRE

The HEART score was developed to improve risk stratification in chest pain patients in the emergency department (ED). This thesis describes series of validation studies of the HEART score and sub studies for individual elements of the score. The predictive value of the HEART score for the occurrence of major cardiovascular events (MACE) in chest pain patients in the ED has been determined in a series of four scientific investigations: two retrospective and two prospective studies, mostly ...

Backus, B. E.

2012-01-01

330

The FACT score in predicting pneumococcal antibody levels in asthmatics.  

Science.gov (United States)

Abstract Background: There is no measure currently available to identify asthmatics with potential immune incompetence. Objective: We propose use of a novel scoring system called the FACT score, which is formulated based on four parameters: (1) Family history of asthma, (2) Atopic conditions, (3) Bacterial colonization and (4) Th1 versus Th2 immune profile. Methods: This was a cross-sectional study involving 16 asthmatics and 14 non-asthmatics. The first two parameters of the FACT score were obtained via a chart review and interview. For the third parameter, nasopharyngeal swab samples were cultured. The ratio of interleukin-5 to interferon-gamma for each patient was measured by peripheral blood mononuclear cells cultured with house dust mite. Antibodies to 23 pneumococcal antigens were used for humoral immunity. Results: The FACT scores for asthmatics (mean?±?SD: 5.2?±?1.87) were higher than those for non-asthmatics (mean?±?SD: 3.3?±?1.5) (p?=?0.008). Of the 16 asthmatics, 7 (44%) had 12 or more positive serotype-specific polysaccharide antibodies, whereas 12 of 14 (86%) of non-asthmatics subjects had 12 or more positive serotype-specific polysaccharide antibodies (p?=?0.014). Overall, the FACT score was inversely correlated with the number of positive serotype-specific antibody levels [rho (?)?=?-0.38, p?=?0.04]. The proportions of subjects with 12 or more positive serotype-specific antibodies among non-asthmatics and asthmatics below and above the median of the FACT scores were 86, 50 and 38%, respectively (p?=?0.052). Conclusions: The FACT score may help us identify a subset of asthmatics with immune incompetence. Study findings need to be replicated in a larger study. PMID:25329680

Podjasek, Jenna C; Jung, Ji A; Kita, Hirohito; Park, Miguel A; Juhn, Young J

2014-10-22

331

Scoring Reliability on the WAIS-R.  

Science.gov (United States)

Wechsler Adult Intelligence Scale-Revised protocols from two vocational counseling clients were scored by 19 psychologists and 20 graduate students. Regardless of scorer's experience level, mechanical scoring error produced summary scores varying by as much as 4 to 18 IQ points. (Author/RC)

Ryan, Joseph J.; And Others

1983-01-01

332

Documentation of radiation-induced oral mucositis. Scoring Systems  

International Nuclear Information System (INIS)

Background: Radiation therapy of tumors in the head and neck region is frequently associated with severe side effects in the oral mucosa which often necessitate interruption of the prescribed treatment protocol. In order to compare therapeutic strategies and, more important, in order to perform multicenter studies, generally accepted scoring systems have to be applied for uniform documentation of the oral mucosal response. Methods: Different scoring protocols are found in the literature. The scoring protocols most widely accepted are the CTC classification and the RTOG/EORTC classification. These are compared with more detailed systems. Results: In the CTC classification, grading of stomatitis is included in the responses of the gastrointestinal tract and emphasizes dietary effects. For effects of radiation alone or of radiochemotherapy, the RTOG/EORTC system, focusing on therapeutic interventions, has been established. However, there are only minor differences in the grading of mucositis between these 2 protocols. Based on the RTOG/EORTC classification, Maciejewski et al. introduced a classification system with inclusion of the area affected, but also changed the sensitivity of the scores. The latter may be confusing if the source of the system used is not cited in a report. An alternative system was proposed by Dische, which in addition to objective morphologic criteria also includes the symptoms induced by the mucosal response, and hence includes some subjective asnse, and hence includes some subjective aspects reported by the patient. Conclusions: For routine documentation of acute radiation side effects in the oral cavity, the German version of the RTOG/EORTC classification can be recommended. In studies with particular interest in oral mucositis, a more sensitive scoring system may be applied. In any publication concerning mucositis, a table or a detailed description of the system used should be included. (orig.)

333

Relationship between motor performance and physical fitness score in 7- to 8-year-old children. DOI: 10.5007/1980-0037.2011v13n2p94  

Directory of Open Access Journals (Sweden)

Full Text Available There are many tests for the evaluation of motor performance or physical fitness that take into account different criteria such as movement forms and patterns, time, distance, and repetitions of each task for the analysis of performance. The aim of this study was to investigate the relationship between motor performance and physical fitness scores in children. Fifty children of both genders aged 7 to 8 years (25 boys and 25 girls participated in this study. The Test of Gross Motor Development – Second Edition (TGMD-2 was used for the evaluation of motor performance. Physical fitness was assessed by three specific tests proposed by the American Alliance for Health, Physical Education, Recreation and Dance (AAHPERD. The results showed statistical significance and weak correlations among some skills such as run, horizontal jump, hop, leap, underhand roll, and medicine ball throw. The equivalent use of both tests may not be adequate since each test has its own peculiarities in terms of assessment criteria.

Patrik Felipe Nazario

2011-03-01

334

Cumulative t-link threshold models for the genetic analysis of calving ease scores  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract In this study, a hierarchical threshold mixed model based on a cumulative t-link specification for the analysis of ordinal data or more, specifically, calving ease scores, was developed. The validation of this model and the Markov chain Monte Carlo (MCMC algorithm was carried out on simulated data from normally and t4 (i.e. a t-distribution with four degrees of freedom distributed populations using the deviance information criterion (DIC and a pseudo Bayes factor (PBF measure to validate recently proposed model choice criteria. The simulation study indicated that although inference on the degrees of freedom parameter is possible, MCMC mixing was problematic. Nevertheless, the DIC and PBF were validated to be satisfactory measures of model fit to data. A sire and maternal grandsire cumulative t-link model was applied to a calving ease dataset from 8847 Italian Piemontese first parity dams. The cumulative t-link model was shown to lead to posterior means of direct and maternal heritabilities (0.40 ± 0.06, 0.11 ± 0.04 and a direct maternal genetic correlation (-0.58 ± 0.15 that were not different from the corresponding posterior means of the heritabilities (0.42 ± 0.07, 0.14 ± 0.04 and the genetic correlation (-0.55 ± 0.14 inferred under the conventional cumulative probit link threshold model. Furthermore, the correlation (> 0.99 between posterior means of sire progeny merit from the two models suggested no meaningful rerankings. Nevertheless, the cumulative t-link model was decisively chosen as the better fitting model for this calving ease data using DIC and PBF.

Tempelman Robert J

2003-09-01

335

Cumulative t-link threshold models for the genetic analysis of calving ease scores.  

Science.gov (United States)

In this study, a hierarchical threshold mixed model based on a cumulative t-link specification for the analysis of ordinal data or more, specifically, calving ease scores, was developed. The validation of this model and the Markov chain Monte Carlo (MCMC) algorithm was carried out on simulated data from normally and t4 (i.e. a t-distribution with four degrees of freedom) distributed populations using the deviance information criterion (DIC) and a pseudo Bayes factor (PBF) measure to validate recently proposed model choice criteria. The simulation study indicated that although inference on the degrees of freedom parameter is possible, MCMC mixing was problematic. Nevertheless, the DIC and PBF were validated to be satisfactory measures of model fit to data. A sire and maternal grandsire cumulative t-link model was applied to a calving ease dataset from 8847 Italian Piemontese first parity dams. The cumulative t-link model was shown to lead to posterior means of direct and maternal heritabilities (0.40 +/-0.06, 0.11 +/- 0.04) and a direct maternal genetic correlation (-0.58 +/- 0.15) that were not different from the corresponding posterior means of the heritabilities (0.42 +/- 0.07, 0.14 +/- 0.04) and the genetic correlation (-0.55 +/- 0.14) inferred under the conventional cumulative probit link threshold model. Furthermore, the correlation (> 0.99) between posterior means of sire progeny merit from the two models suggested no meaningful rerankings. Nevertheless, the cumulative t-link model was decisively chosen as the better fitting model for this calving ease data using DIC and PBF. PMID:12939202

Kizilkaya, Kadir; Carnier, Paolo; Albera, Andrea; Bittante, Giovanni; Tempelman, Robert J

2003-01-01

336

Prognóstico dos casos de pancreatite aguda pelo escore de PANC 3 / Prognosis of acute pancreatitis by PANC 3 score  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese RACIONAL: A pancreatite aguda é doença de grande importância na prática clínica, definida como inflamação do pâncreas podendo levar ao envolvimento de tecidos locais ou acometimento de outros órgãos de forma sistêmica, necessitando nesses casos de cuidados em terapia intensiva. OBJETIVO: Analisar o [...] sistema simplificado de estratificação de PANC 3, correlacionando-o com o escore de Ranson para definição prognóstica de casos de pancreatite aguda. MÉTODO: Foi realizado um estudo observacional, prospectivo em que foram avaliados 65 pacientes que foram diagnosticados com quadro de pancreatite aguda. RESULTADOS: Obteve para o PANC 3 sensibilidade de 31,25%; especificidade de 100%; valor preditivo positivo de 100%; valor preditivo negativo de 81,66% e acurácia de 83,07%. CONCLUSÕES: Os critérios de PANC 3 têm sua validade na definição de gravidade e prognóstico da pancreatite aguda, não como método substituto, mas como método a ser associado aos critérios de Ranson, principalmente pela sua alta acurácia, valor preditivo positivo e especificidade. Abstract in english BACKGROUND: Acute pancreatitis is a disease of great importance in clinical practice, defined as an inflammatory process of the pancreas that may involve local tissues or affect other organs in a systemic manner, requiring, in such cases, an intensive care. AIM: To analyze the simplified stratificat [...] ion system of the PANC 3 score, correlating it with the Ranson score, for the prognostic definition of cases of acute pancreatitis. METHOD: Was conducted a prospective, observational study in which were evaluated 65 patients who were diagnosed with acute pancreatitis. RESULTS: PANC 3 showed sensitivity, 31.25%; specificity,100%; positive predictive value, 100%; negative predictive value, 81.66% and accuracy, 83.07%. CONCLUSIONS: The PANC 3 criteria are applicable to define the severity and the prognosis of acute pancreatitis, and are not a substitute method, but rather a method to be associated with the Ranson criteria, mainly due to its high accuracy, positive predictive value and specificity.

James Ken, Fukuda; Orli, Franzon; Fernando de Oliveira, Resende-Filho; Nicolau Fernandes, Kruel; Thiago Alessandro, Ferri.

2013-06-01

337

Extracting temporal constraints from clinical research eligibility criteria using conditional random fields.  

Science.gov (United States)

Temporal constraints are present in 38% of clinical research eligibility criteria and are crucial for screening patients. However, eligibility criteria are often written as free text, which is not amenable for computer processing. In this paper, we present an ontology-based approach to extracting temporal information from clinical research eligibility criteria. We generated temporal labels using a frame-based temporal ontology. We manually annotated 150 free-text eligibility criteria using the temporal labels and trained a parser using Conditional Random Fields (CRFs) to automatically extract temporal expressions from eligibility criteria. An evaluation of an additional 60 randomly selected eligibility criteria using manual review achieved an overall precision of 83%, a recall of 79%, and an F-score of 80%. We illustrate the application of temporal extraction with the use cases of question answering and free-text criteria querying. PMID:22195142

Luo, Zhihui; Johnson, Stephen B; Lai, Albert M; Weng, Chunhua

2011-01-01

338

THE EFFICIENCY OF TENNIS DOUBLES SCORING SYSTEMS  

OpenAIRE

In this paper a family of scoring systems for tennis doubles for testing the hypothesis that pair A is better than pair B versus the alternative hypothesis that pair B is better than A, is established. This family or benchmark of scoring systems can be used as a benchmark against which the efficiency of any doubles scoring system can be assessed. Thus, the formula for the efficiency of any doubles scoring system is derived. As in tennis singles, one scoring system based on the play-the-loser ...

Geoff Pollard; Graham Pollard

2010-01-01

339

Scoring clinical competencies of learners: A quantitative descriptive study  

OpenAIRE

This article reports the correlation between different clinical assessors’ scoring of learners’ clinical competencies in order to exclude any possible extraneous variables with regard to reasons for poor clinical competencies of learners. A university in Gauteng, South Africa provides a learning programme that equips learners with clinical knowledge, skills and values in the assessment, diagnosis, treatment and care of patients presenting at primary health care (PHC) facilities. The resea...

Ann Müller; Sonya Beukes; Magobe, Nomasonto B. D.

2011-01-01

340

Automatic detection and quantification of the Agatston coronary artery calcium score on contrast computed tomography angiography.  

Science.gov (United States)

Potentially, Agatston coronary artery calcium (CAC) score could be calculated on contrast computed tomography coronary angiography (CTA). This will make a separate non-contrast CT scan superfluous. This study aims to assess the performance of a novel fully automatic algorithm to detect and quantify the Agatston CAC score in contrast CTA images. From a clinical registry, 20 patients were randomly selected for each CAC category (i.e. 0, 1-99, 100-399, 400-999, ?1,000). The Agatston CAC score on non-contrast CT was calculated manually, while the novel algorithm was used to automatically detect and quantify Agatston CAC score in contrast CTA images. The resulting Agatston CAC scores were validated against the non-contrast images. A total of 100 patients (60 ± 11 years, 63 men) were included. The median CAC score on non-contrast CT was 145 (IQR 5-760), whereas the contrast CTA CAC score was 170 (IQR 23-594) (P = 0.004). The automatically computed CAC score showed a high correlation (R = 0.949; P CTA is feasible and showed high correlation with non-contrast CT CAC score. This could imply a radiation dose reduction and time saving by omitting the non-contrast scan. PMID:25159031

Ahmed, Wehab; de Graaf, Michiel A; Broersen, Alexander; Kitslaar, Pieter H; Oost, Elco; Dijkstra, Jouke; Bax, Jeroen J; Reiber, Johan H C; Scholte, Arthur J

2015-01-01

341

Can Students Predict Their Scores in Exams?  

Science.gov (United States)

This article describes a statistical study in which students were asked to predict their own exam scores. The actual and predicted scores of 61 students in 6 years of an advanced plant genetics course and the differences between their actual and predicted scores were analyzed by various statistical measures. An overall mean difference between actual and predicted scores showed that the students, on average, were able to predict their scores within 5 percent of the actual value. However, students were not able to predict their exam scores accurately or precisely; the difference between actual and predicted scores was statistically different from zero. In addition, student demographic types such as age, GPA, or level of education were not significant factors for accuracy in predicting marks on the exam.

Sharma, H.

342

Novel histologic scoring system for long-term allograft fibrosis after liver transplantation in children.  

Science.gov (United States)

The existing systems for scoring fibrosis were not developed to evaluate transplanted livers. Our aim was to design and validate a novel fibrosis scoring system specifically adapted to assess liver allograft fibrosis (LAF). Clinical data, histology, transient elastography (TE) and AST/platelet ratio index (APRI) were reviewed in 38 pediatric liver transplant (LT) recipients. Protocol liver biopsies performed at 6 months and 7 years post-LT were reviewed by three pathologists who assessed LAF using the METAVIR and Ishak systems. LAF was also scored separately in portal (0-3), sinusoidal (0-3) and centrolobular areas (0-3). Scoring evaluations were correlated with fibrosis quantification using morphometry, and also with TE and APRI. Statistical correlations between morphometry and METAVIR were 0.571 (p LAF than the existing scoring system and may become a practical tool for staging fibrosis in LT. PMID:22882699

Venturi, C; Sempoux, C; Bueno, J; Ferreres Pinas, J C; Bourdeaux, C; Abarca-Quinones, J; Rahier, J; Reding, R

2012-11-01

343

Web site Evaluation Criteria  

Directory of Open Access Journals (Sweden)

Full Text Available The ever-increasing evolution of the Internet and the growing number of the resources accessible through this medium, has turned the issue of resource evaluation of the internet-based information into a controversial and cogent issue. By nature, the internet milieu is uncontrollable. It concomitantly contains both verifiable and unverifiable information. Thus it behooves the internet users to develop resource evaluation and critical thinking skills in order to discern appropriate quality resources. Through review and comparison of the available checklists, the present paper endeavors to offer criteria for website evaluation

Mojdgan binesh

2008-07-01

344

Accurate and diverse recommendations via eliminating redundant correlations  

International Nuclear Information System (INIS)

In this paper, based on a weighted projection of a bipartite user-object network, we introduce a personalized recommendation algorithm, called network-based inference (NBI), which has higher accuracy than the classical algorithm, namely collaborative filtering. In NBI, the correlation resulting from a specific attribute may be repeatedly counted in the cumulative recommendations from different objects. By considering the higher order correlations, we design an improved algorithm that can, to some extent, eliminate the redundant correlations. We test our algorithm on two benchmark data sets, MovieLens and Netflix. Compared with NBI, the algorithmic accuracy, measured by the ranking score, can be further improved by 23 per cent for MovieLens and 22 per cent for Netflix. The present algorithm can even outperform the Latent Dirichlet Allocation algorithm, which requires much longer computational time. Furthermore, most previous studies considered the algorithmic accuracy only; in this paper, we argue that the diversity and popularity, as two significant criteria of algorithmic performance, should also be taken into account. With more or less the same accuracy, an algorithm giving higher diversity and lower popularity is more favorable. Numerical results show that the present algorithm can outperform the standard one simultaneously in all five adopted metrics: lower ranking score and higher precision for accuracy, larger Hamming distance and lower intra-similarity for divestance and lower intra-similarity for diversity, as well as smaller average degree for popularity.

345

Accurate and diverse recommendations via eliminating redundant correlations  

Energy Technology Data Exchange (ETDEWEB)

In this paper, based on a weighted projection of a bipartite user-object network, we introduce a personalized recommendation algorithm, called network-based inference (NBI), which has higher accuracy than the classical algorithm, namely collaborative filtering. In NBI, the correlation resulting from a specific attribute may be repeatedly counted in the cumulative recommendations from different objects. By considering the higher order correlations, we design an improved algorithm that can, to some extent, eliminate the redundant correlations. We test our algorithm on two benchmark data sets, MovieLens and Netflix. Compared with NBI, the algorithmic accuracy, measured by the ranking score, can be further improved by 23 per cent for MovieLens and 22 per cent for Netflix. The present algorithm can even outperform the Latent Dirichlet Allocation algorithm, which requires much longer computational time. Furthermore, most previous studies considered the algorithmic accuracy only; in this paper, we argue that the diversity and popularity, as two significant criteria of algorithmic performance, should also be taken into account. With more or less the same accuracy, an algorithm giving higher diversity and lower popularity is more favorable. Numerical results show that the present algorithm can outperform the standard one simultaneously in all five adopted metrics: lower ranking score and higher precision for accuracy, larger Hamming distance and lower intra-similarity for diversity, as well as smaller average degree for popularity.

Zhou Tao; Su Riqi; Liu Runran; Jiang Luoluo; Wang Binghong [Department of Modern Physics and Nonlinear Science Center, University of Science and Technology of China, Hefei Anhui 230026 (China); Zhang Yicheng [Department of Physics, University of Fribourg, Chemin du Musee 3, CH-1700 Fribourg (Switzerland)], E-mail: bhwang@ustc.edu.cn

2009-12-15

346

Accurate and diverse recommendations via eliminating redundant correlations  

Science.gov (United States)

In this paper, based on a weighted projection of a bipartite user-object network, we introduce a personalized recommendation algorithm, called network-based inference (NBI), which has higher accuracy than the classical algorithm, namely collaborative filtering. In NBI, the correlation resulting from a specific attribute may be repeatedly counted in the cumulative recommendations from different objects. By considering the higher order correlations, we design an improved algorithm that can, to some extent, eliminate the redundant correlations. We test our algorithm on two benchmark data sets, MovieLens and Netflix. Compared with NBI, the algorithmic accuracy, measured by the ranking score, can be further improved by 23 per cent for MovieLens and 22 per cent for Netflix. The present algorithm can even outperform the Latent Dirichlet Allocation algorithm, which requires much longer computational time. Furthermore, most previous studies considered the algorithmic accuracy only; in this paper, we argue that the diversity and popularity, as two significant criteria of algorithmic performance, should also be taken into account. With more or less the same accuracy, an algorithm giving higher diversity and lower popularity is more favorable. Numerical results show that the present algorithm can outperform the standard one simultaneously in all five adopted metrics: lower ranking score and higher precision for accuracy, larger Hamming distance and lower intra-similarity for diversity, as well as smaller average degree for popularity.

Zhou, Tao; Su, Ri-Qi; Liu, Run-Ran; Jiang, Luo-Luo; Wang, Bing-Hong; Zhang, Yi-Cheng

2009-12-01

347

Scoring sacroiliac joints by magnetic resonance imaging. A multiple-reader reliability experiment.  

DEFF Research Database (Denmark)

Magnetic resonance imaging (MRI) of the sacroiliac (SI) joints and the spine is increasingly important in the assessment of inflammatory activity and structural damage in clinical trials with patients with ankylosing spondylitis (AS). We investigated inter-reader reliability and sensitivity to change of several scoring systems to assess disease activity and change in disease activity in patients with AS. Twenty sets of consecutive MRI, derived from a randomized clinical trial comparing an active drug with placebo and selected on the basis of the presence of activity at baseline, were presented electronically to 7 experienced readers from different countries (Europe, Canada). Readers scored the MRI by 3 different methods including: a global score (grading activity per SI joint); a more comprehensive global score (grading activity per SI joint per quadrant); and a detailed scoring system [Spondyloarthritis Research Consortium of Canada (SPARCC) scoring system], which scores 6 images, divided into quadrants, with additional scores for 'depth' and 'intensity.' A fourth and a fifth scoring system were constructed afterwards. The fourth method included the SPARCC score minus the additional scores for 'depth' and 'intensity,' and the fifth method included the SPARCC slice with the maximum score. Inter-reader reliability was investigated by calculating intraclass correlation coefficients (ICC) for all readers together and for all possible reader pairs. Sensitivity to change was investigated by calculating standardized response means (SRM) on change scores that were made positive. Overall inter-reader ICC per method were between 0.47 and 0.58 for scoring status, and between 0.40 and 0.53 for scoring change. ICC per possible reader pairs showed much more fluctuation per method, with lowest observed values close to zero (no agreement) and highest observed values over 0.80 (excellent agreement). In general, agreement of status scores was somewhat better than agreement of change scores, and agreement of the comprehensive SPARCC scoring system was somewhat better than agreement of the more condensed systems. Sensitivity to change differed per reader, but in general was somewhat better for the comprehensive SPARCC system. This experiment under 'real life,' far from optimal conditions demonstrates the feasibility of scoring exercises for method comparison, provides evidence for the reliability and sensitivity to change of scoring systems to be used in assessing activity of SI joints in clinical trials, and sets the conditions for further validation research in this field

Landewe, Robert B.M.; Hermann, Kay Geert A

2005-01-01

348

Effects of endorphin massage on B-endorphin level and Edinburgh Postnatal Depression Scale (EPDS) score in women with postpartum blues  

OpenAIRE

Purpose: This study aimed to investigate the effects of endorphin massage on B-endorphin level and EPDS score in women with postpartum blues. Material and Methods: Twenty postpartum women volunteered for the study. All of them gave written consent regarding their participation. The inclusion criteria were mother with post partum blues at third day post partum and EPDS score > 9, while the exclusion criteria were mother with history of depression post partum. The measurement of marker (B-e...

Hidayati Hidayati; Wisnu Barlianto; Siti Candra Windu Baktiyani

2014-01-01

349

Genetic parameters of two methods of scoring cow fighting ability  

Directory of Open Access Journals (Sweden)

Full Text Available In this study, two different methods of scoring were implemented and compared in reason to assign a correct phenotypic value to cow fighting ability, and the variance components of the trait were estimated. Moreover, it was investigated the correlation of the estimated breeding values (EBVs for fighting with the EBVs for the linear type traits muscularity. A scoring method mainly based on position (PS and a method considering opponents’ performances (CPS were compared and used in genetic analyses. A correlation of 0.75 between EBVs associated to PS and CPS was obtained, and ANOVAs considering alternatively PS and CPS indicated almost the same magnitude of the different sources of variation included (R2=0.50 and 0.52 for PS and CPS, respectively. Heritability estimates with the REML method were 0.099 (S.E.=0.005 for PS and 0.034 (S.E.=0.007 for CPS. Pearson and Spearman correlations between both indexes and ranks were no significant. Finally, an evaluation of the fitness of the two models revealed that PS is the better system for scoring, although CPS was designed to account also for the opponents.

Roberto Mantovani

2010-01-01

350

Improving personality facet scores with multidimensional computer adaptive testing : an illustration with the NEO PI-R  

DEFF Research Database (Denmark)

Narrowly defined personality facet scores are commonly reported and used for making decisions in clinical and organizational settings. Although these facets are typically related, scoring is usually carried out for a single facet at a time. This method can be ineffective and time consuming when personality tests contain many highly correlated facets. This article investigates the possibility of increasing the precision of the NEO PI-R facet scores by scoring items with multidimensional item response theory and by efficiently administering and scoring items with multidimensional computer adaptive testing (MCAT). The increase in the precision of personality facet scores is obtained from exploiting the correlations between the facets. Results indicate that the NEO PI-R could be substantially shorter without attenuating precision when the MCAT methodology is used. Furthermore, the study shows that the MCAT methodology is particularly appropriate for constructs that have many highly correlated facets.

Makransky, Guido; Mortensen, Erik Lykke

2013-01-01

351

An analysis of electrocardiographic criteria for determining left ventricular hypertrophy  

OpenAIRE

OBJECTIVE: To determine the most sensitive criterion for the detection of left ventricular hypertrophy according to echocardiographically defined left ventricular mass. METHODS: The Sokolow-Lyon voltage, Sokolow-Lyon-Rappaport, Cornell voltage duration product, White-Bock, and Romhilt-Estes point scoring criteria were compared with left ventricular mass index, corrected for body surface, obtained from the echocardiograms of 306 outpatients (176 females, 130 males), of all age groups. RESULTS:...

Gasperin Carlos Alberto; Germiniani Helio; Facin Carlos Roberto; Souza Admar Moraes de; Cunha Cláudio Leinig Pereira da

2002-01-01

352

Composite cerebellar functional severity score: validation of a quantitative score of cerebellar impairment.  

Science.gov (United States)

Reliable and easy to perform functional scales are a prerequisite for future therapeutic trials in cerebellar ataxias. In order to assess the specificity of quantitative functional tests of cerebellar dysfunction, we investigated 123 controls, 141 patients with an autosomal dominant cerebellar ataxia (ADCA) and 53 patients with autosomal dominant spastic paraplegia (ADSP). We evaluated four different functional tests (nine-hole pegboard, click, tapping and writing tests), in correlation with the scale for the assessment and rating of cerebellar ataxia (SARA), the scale of functional disability on daily activities (part IV of the Huntington disease rating scale), depression (the Public Health Questionnaire PHQ-9) and the EQ-5D visual analogue scale for self-evaluation of health status. There was a significant correlation between each functional test and a lower limb score. The performance of controls on the functional tests was significantly correlated with age. Subsequent analyses were therefore adjusted for this factor. The performances of ADCA patients on the different tests were significantly worse than that of controls and ADSP patients; there was no difference between ADSP patients and controls. Linear regression analysis showed that only two independent tests, the nine-hole pegboard and the click test on the dominant side (P validated method for assessing cerebellar ataxia over a wide range of severity, and will be particularly useful for discriminating paucisymptomatic carriers from affected patients and for evaluating disease progression in future therapeutic trials. PMID:18378516

du Montcel, Sophie Tezenas; Charles, Perrine; Ribai, Pascale; Goizet, Cyril; Le Bayon, Alice; Labauge, Pierre; Guyant-Maréchal, Lucie; Forlani, Sylvie; Jauffret, Celine; Vandenberghe, Nadia; N'guyen, Karine; Le Ber, Isabelle; Devos, David; Vincitorio, Carlo-Maria; Manto, Mario-Ubaldo; Tison, François; Hannequin, Didier; Ruberg, Merle; Brice, Alexis; Durr, Alexandra

2008-05-01

353

Diagnostic accuracy of three scoring methods for the Davidson Trauma Scale among U.S. military veterans.  

Science.gov (United States)

Self-report questionnaires are frequently used to identify PTSD among U.S. military personnel and Veterans. Two common scoring methods used to classify PTSD include: (1) a cut score threshold and (2) endorsement of PTSD symptoms meeting DSM-IV-TR symptom cluster criteria (SCM). A third method requiring a cut score in addition to SCM has been proposed, but has received little study. The current study examined the diagnostic accuracy of three scoring methods for the Davidson Trauma Scale (DTS) among 804 Afghanistan and Iraq war-era military Service Members and Veterans. Data were weighted to approximate the prevalence of PTSD and other Axis I disorders in VA primary care. As expected, adding a cut score criterion to SCM improved specificity and positive predictive power. However, a cut score of 68-72 provided optimal diagnostic accuracy. The utility of the DTS, the role of baseline prevalence, and recommendations for future research are discussed. PMID:24216181

McDonald, Scott D; Thompson, NiVonne L; Stratton, Kelcey J; Calhoun, Patrick S

2014-03-01

354

A generic impact-scoring system applied to alien mammals in Europe.  

Science.gov (United States)

We present a generic scoring system that compares the impact of alien species among members of large taxonomic groups. This scoring can be used to identify the most harmful alien species so that conservation measures to ameliorate their negative effects can be prioritized. For all alien mammals in Europe, we assessed impact reports as completely as possible. Impact was classified as either environmental or economic. We subdivided each of these categories into five subcategories (environmental: impact through competition, predation, hybridization, transmission of disease, and herbivory; economic: impact on agriculture, livestock, forestry, human health, and infrastructure). We assigned all impact reports to one of these 10 categories. All categories had impact scores that ranged from zero (minimal) to five (maximal possible impact at a location). We summed all impact scores for a species to calculate "potential impact" scores. We obtained "actual impact" scores by multiplying potential impact scores by the percentage of area occupied by the respective species in Europe. Finally, we correlated species' ecological traits with the derived impact scores. Alien mammals from the orders Rodentia, Artiodactyla, and Carnivora caused the highest impact. In particular, the brown rat (Rattus norvegicus), muskrat (Ondathra zibethicus), and sika deer (Cervus nippon) had the highest overall scores. Species with a high potential environmental impact also had a strong potential economic impact. Potential impact also correlated with the distribution of a species in Europe. Ecological flexibility (measured as number of different habitats a species occupies) was strongly related to impact. The scoring system was robust to uncertainty in knowledge of impact and could be adjusted with weight scores to account for specific value systems of particular stakeholder groups (e.g., agronomists or environmentalists). Finally, the scoring system is easily applicable and adaptable to other taxonomic groups. PMID:19604296

Nentwig, Wolfgang; Kühnel, Elfi; Bacher, Sven

2010-02-01

355

Evaluation of a Lameness Scoring System for Dairy Cows  

DEFF Research Database (Denmark)

Lameness is a major problem in dairy production both in terms of reduced production and compromised animal welfare. A 5-point lameness scoring system was developed based on previously published systems, but optimized for use under field conditions. The scoring system included the words "in most cases" in the descriptions of the clinical signs evaluated. This was done to avoid a situation in which cows might not fit into any of the categories. Additionally, a number of clinical signs used in other lameness scoring systems, considered of less importance in relation to lameness, were not included. Only clinical signs were included that could easily be assessed within a few seconds from a distance. The scoring system was evaluated with intra-and interobserver agreement using kappa statistics. The evaluation was done before and after training 5 observers. Weighted kappa values ranged from 0.38 to 0.78 for intraobserver agreement, with mean kappa values across all observers of 0.60 and 0.53 before and after training, respectively. Weighted kappa values ranged from 0.24 to 0.68 for interobserver agreement, with mean kappa values across all pairs of observers of 0.48 and 0.52 before and after training, respectively. Training had only a limited positive effect on intra- and interobserver agreement. Additionally, how the different lameness categories are distributed along a theoretical scale representing the full spectrum of lameness from "absolutely normal gait" to "as lame as a cow can possibly be" was evaluated. This evaluation was done using the polychoric correlation coefficient. The estimated within-observer polychoric correlation coefficient ranged from 0.76 to 0.96, and there were no significant differences between the thresholds used to classify cows into different lameness categories by different observers before or after training. In conclusion, the results suggest that the lameness categories were not equidistant and the scoring system has reasonable reliability in terms of intra- and interobserver agreement

Thomsen, P T; Munksgaard, L

2008-01-01

356

Evaluation of a lameness scoring system for dairy cows.  

Science.gov (United States)

Lameness is a major problem in dairy production both in terms of reduced production and compromised animal welfare. A 5-point lameness scoring system was developed based on previously published systems, but optimized for use under field conditions. The scoring system included the words "in most cases" in the descriptions of the clinical signs evaluated. This was done to avoid a situation in which cows might not fit into any of the categories. Additionally, a number of clinical signs used in other lameness scoring systems, considered of less importance in relation to lameness, were not included. Only clinical signs were included that could easily be assessed within a few seconds from a distance. The scoring system was evaluated with intra-and interobserver agreement using kappa statistics. The evaluation was done before and after training 5 observers. Weighted kappa values ranged from 0.38 to 0.78 for intraobserver agreement, with mean kappa values across all observers of 0.60 and 0.53 before and after training, respectively. Weighted kappa values ranged from 0.24 to 0.68 for interobserver agreement, with mean kappa values across all pairs of observers of 0.48 and 0.52 before and after training, respectively. Training had only a limited positive effect on intra- and interobserver agreement. Additionally, how the different lameness categories are distributed along a theoretical scale representing the full spectrum of lameness from "absolutely normal gait" to "as lame as a cow can possibly be" was evaluated. This evaluation was done using the polychoric correlation coefficient. The estimated within-observer polychoric correlation coefficient ranged from 0.76 to 0.96, and there were no significant differences between the thresholds used to classify cows into different lameness categories by different observers before or after training. In conclusion, the results suggest that the lameness categories were not equidistant and the scoring system has reasonable reliability in terms of intra- and interobserver agreement. PMID:18096932

Thomsen, P T; Munksgaard, L; Tøgersen, F A

2008-01-01

357

Argyrophilic nucleolar organizer region counts and Ki-67 scores in human renal cell carcinoma.  

Science.gov (United States)

The proliferative activity of 21 cases of renal cell carcinoma has been investigated by means of monoclonal antibody Ki-67 and Nucleolar Organizer Regions (AgNORs) analysis. The correlation between AgNOR counts and Ki-67 scores was only slightly significant (r = 0.53, r2 = 0.28) as determined by linear regression. Positive correlation was found between Ki-67 scores and tumour histologic grade. However, no correlation was observed between Ki-67 scores and tumour pathologic stage and between AgNOR counts and tumour histologic grade and/or pathologic stage. The results suggest that AgNOR counts cannot replace Ki-67 scores in evaluating the proliferative activity of renal cell carcinoma and that such activity and both histologic grade and pathologic stage seem to be independent parametres. PMID:1715079

Pich, A; Valente, G; Azzoni, L; Stramignoni, A; Margaria, E; Tasso, M

1991-05-01

358

Influence of scoring parameter settings on Agatston and volume scores for coronary calcification  

International Nuclear Information System (INIS)

Current multi-detector CT and electron beam tomography (EBT) technology enables the evaluation of coronary calcification. Multiple software packages are available to quantify calcification using several scoring algorithms implementing user-definable scoring parameters. We investigated the effect of scoring parameters on the calcium score outcome. Three parameters (four-connected or eight-connected, lesion size threshold and interpolation) are evaluated. Their theoretical influence on the scoring outcome is shown using simplified examples. To evaluate the effect in real data, we performed calcium scoring on randomly chosen EBT scans from 50 participants in an epidemiological study. Both the Agatston and volume scores were calculated. Changing from eight-connected to four-connected connectivity decreased both Agatston and volume scores (mean variability Agatston 3.15% and volume score -3.52%). Decreasing the threshold from 4 to 2 pixels increased the calcium scores because smaller lesions were also selected as calcified plaques (mean variability Agatston 16.23% and volume score 18.66%). Finally, the use of interpolation had a large negative effect on the volume score (mean variability -29.67%) and almost no effect on the Agatston score. Parameter settings in software for quantification for coronary calcification affect the calcium score outcome. Therefore, parameter settings for calcium scoring should be standardized. (orig.)

359

Sonographic Scoring for Operating Room Triage in Trauma  

Directory of Open Access Journals (Sweden)

Full Text Available Objective: The focused assessment with sonography for trauma (FAST exam is a routine diagnostic adjunct in the initial assessment of blunt trauma victims but lacks the ability to reliably predict which patients require laparotomy. Physiologic data play a major role in decision making regarding the need for emergent laparotomy versus further diagnostic testing or observation. The need for laparotomy often influences the decision to transfer the patient to a trauma center. We set out to derive a simple scoring system using both ultrasound findings and immediately available physiologic data that would predict which patients require laparotomy.Methods: We conducted a prospective observational study of victims of blunt trauma who presented to a Level 1 Trauma Center. We collected FAST findings, physiologic data, and lab values. A previously-developed ultrasound scoring system was applied to the FAST findings. Patients were followed to determine if they underwent laparotomy. We used logistic regression analysis to determine which variables correlated with laparotomy and developed a new scoring system.Results: We enrolled a convenience sample of 1,393 patients. A simple scoring system (range 0-6 was developed that included both FAST findings and vital signs (heart rate and blood pressure. Patients with a score of 0 or 1 had a less than 1% chance of requiring laparotomy.Conclusion: The combination of FAST findings with vital signs in our scoring system predicted which victims of blunt trauma did not undergo laparotomy. Applying this to trauma patients who present to non-trauma centers could help prevent unnecessary patient transfers. This derivation set must be validated prior to use in patient care. [West J Emerg Med. 2010; 11(2:138-143.

Raghavendran, Krishnan MD

2010-05-01

360

Awareness and use of cardiovascular risk scores by family physicians in southeastern Ontario  

Directory of Open Access Journals (Sweden)

Full Text Available Background: Our objective was to determine the assessment of cardiovascular risk by family physicians. Methods: A questionnaire was sent by mail or fax regarding both awareness and use of the various CV risk scores in southeastern Ontario. Results: Of 181 family physicians surveyed, 96% were aware of at least one CV risk score and 40% were aware of the JUPITER study. Despite this awareness, 72% simply counted risk factors to assess risk, rather than to calculate risk using established scoring methods. Only 23% used the JUPITER study criteria. This suggests an under-estimated of overall CV risk by family physician’s practicing in southeastern Ontario. Interpetation: Cardiovascular risk in primary care is being underestimated in southeastern Ontario. Additional knowledge translation strategies are required to enhance the family physician’s awareness and use of established risk scoring methods if we are to reduce the burden of CV disease.

Murray F. Matangi

2013-11-01

361

Utilidad de una escala diagnóstica en casos de apendicitis aguda Utility of a diagnostic scale scoring system in acute appendicitis  

Directory of Open Access Journals (Sweden)

Full Text Available Objetivo. Evaluar las puntuaciones de la escala diagnóstica de Alvarado en una serie de casos clínicos intervenidos quirúrgicamente con diagnóstico de apendicitis aguda. Materiales y métodos. Se trata de un estudio descriptivo de corte transversal. Se revisaron los registros clínicos de 101 casos sometidos a cirugía con diagnóstico de apendicitis aguda en el Hospital Regional de Duitama de enero a marzo de 2010. Para cada uno se estimó la puntuación alcanzada en la escala diagnóstica de Alvarado y se correlacionó con el resultado histopatológico, el tiempo de evolución, el sexo y la edad del paciente. Resultados. El 56,6 % correspondió a hombres y hubo 65,4 % de menores de 30 años. El tiempo promedio de evolución fue de de 44,6 horas. Se encontró asociación positiva entre evoluciones mayores de 36 horas y necrosis del apéndice (pObjective. To assess the Alvarado's diagnosis scores in a series of patients undergoing surgery with diagnosis of acute appendicitis. Materials and Methods. Descriptive, cross sectional study. The medical records of 101 cases that underwent surgery with diagnosis of acute appendicitis at Duitama's Regional Hospital, Duitama, Colombia, during the period January to March of 2010 were reviewed. The scores of the Alvarado's diagnostic scale were correlated with the histopathological results, time evolved before diagnosis, gender and age of the patient. Results. There were 56.6% male and 65.4% of patients were less than 30 years of age, median time evolved before diagnosis was 44.6 hours. Positive association was found between evolved time over 36 hours before diagnosis and necrosis of the appendix (p <0.01. Correlation of the diagnostic Alvarado score and histopathologic findings was 75.2%. The criteria that showed higher discriminating capacity were abdominal pain localized in the lower right quadrant, migration of pain, Blumberg´s sign, leukocytosis and neutrophilia (p <0.001; less discriminatory power were nausea/vomiting, fever, and anorexia. Conclusion. The Alvarado's diagnosis score, can be a very useful diagnostic tool to improve the timely and diagnostic efficacy in the acute appendicitis, especially in the outpatient and emergency services where high-level diagnostic aids such as images are not available.

Juan Manuel Ospina

2011-12-01

362

Weiss criteria in large adrenocortical tumors: A validation study  

Directory of Open Access Journals (Sweden)

Full Text Available Background: Several systems including pathologic criteria alone or in combination with clinical features have been proposed to differentiate between benign and malignant adrenocortical tumors and assess their prognosis. The Weiss system appears to be the most commonly used method for assessing malignancy but there are only a few studies which have evaluated its diagnostic power. Since we see large adrenocortical carcinoma (ACC, we attempt to evaluate the diagnostic power of Weiss system in large ACC. Materials and Methods: In this study clinicopathological characteristics of 42 adrenocortical neoplasms are studied and classified into adrenocortical adenoma (ACA and ACC based on Weiss score of less than or equal to three or greater than three. Results: The histological criteria of Weiss appeared to predict tumor prognosis accurately. Five year survival of patients with Weiss scores of less than or equal to three was 100% compared to 0% of those with Weiss scores greater than three. The average weights of ACA and ACC were 13.0 plus/minus 8.4 grams and 621.1 plus/minus 335.2 grams respectively; average sizes of ACA and ACC were 2.8 plus/minus 1.0 cmsand 13.6 plus/minus 3.7 cms respectively. Conclusion: Weiss score was found to be a good prognostic factor for tumors of the adrenal cortex.

Jain Manoj

2010-04-01

363

24 CFR 902.45 - Management operations scoring and thresholds.  

Science.gov (United States)

...false Management operations scoring and thresholds. 902.45... PUBLIC HOUSING ASSESSMENT SYSTEM PHAS Indicator #3: Management...45 Management operations scoring and thresholds. (a) Scoring. The Management...

2010-04-01

364

24 CFR 902.35 - Financial condition scoring and thresholds.  

Science.gov (United States)

...false Financial condition scoring and thresholds. 902.35... PUBLIC HOUSING ASSESSMENT SYSTEM PHAS Indicator #2: Financial...35 Financial condition scoring and thresholds. (a) Scoring. Under PHAS...

2010-04-01

365

SFR Specific Criteria  

International Nuclear Information System (INIS)

Criteria on Overall Plant System Criterion 42bis: Plant system performance of a sodium-cooled fast reactor. Overall plant system shall be designed considering specific SFR characteristics: –Reactor core configuration: Not in its most reactive configuration - could lead to a positive reactivity insertion due to an unfavourable change in reactor core geometry; –Reactor core reactivity: Sodium void reactivity may be positive in core central region - could lead to positive reactivity insertion due to sodium boiling or gas entrainment; –Sodium coolant thermal/thermal-hydraulic property: High boiling temperature - operate at low pressure with large margin to boiling high thermal conductivity and heat transfer coefficient - large temperature gradient in reactor core and capable decay heat removal by natural circulation; –Sodium chemical property: Chemically active, opaque, solid below 98 °C; Sodium mist and vapour are deposited on the components; Sodium burns in air and intensely reacts with water - propagation of such chemical reactions to reactor core must be prevented

366

7 CFR 1740.8 - Scoring criteria for the grant competition.  

Science.gov (United States)

...subtracting the county's urban population(s) from the total county...all included counties' rural populations. Urban area and county populations...formula is: 100 × [(total population ? urban population)/total...

2010-01-01

367

Local Proper Scoring Rules of Order Two  

CERN Document Server

Scoring rules assess the quality of probabilistic forecasts, by assigning a numerical score based on the predictive distribution and on the event or value that materializes. A scoring rule is proper if it encourages truthful reporting. It is local of order $k$ if the score depends on the predictive density only through its value and the values of its derivatives of order up to $k$ at the realizing event. Complementing fundamental recent work by Parry, Dawid and Lauritzen (2011), we characterize the local proper scoring rules of order two relative to a broad class of Lebesgue densities on the real line, using a different approach. In a data example, we use local and non-local proper scoring rules to assess statistically postprocessed ensemble weather forecasts.

Ehm, Werner

2011-01-01

368