WorldWideScience
 
 
1

Correlation of pre-veterinary admissions criteria, intra-professional curriculum measures, AVMA-COE professional competency scores, and the NAVLE.  

Science.gov (United States)

Data consisting of preadmission criteria scores, annual and final cumulative grade point averages (GPAs), grades from individual professional courses, American Veterinary Medical Association Council on Education (AVMA-COE) Competency scores, annual class rank, and North American Veterinary Licensing Exam (NAVLE) scores were collected on all graduating DVM students at Kansas State University in 2009 and 2010. Associations among the collected data were compared by Pearson correlation. Pre-veterinary admissions criteria infrequently correlated with annual GPAs of Years 1-3, rarely correlated with the AVMA-COE Competencies, and never correlated with the annual GPA of Year 4. Low positive correlations occurred between the NAVLE and the Verbal Graduate Record Examination (GRE) (r=.214), Total GRE (r=.171), and the mean GPA of pre-professional science courses (SGPA) (r=.236). Annual GPAs strongly correlated with didactic course scores. Annual GPAs and final class rank strongly correlated (mean r=-.849), and both strongly correlated with the NAVLE score (NAVLE: GPAs mean r=.628, NAVLE: final class rank r=-.714). Annual GPAs at the end of Years 1-4 weakly correlated or did not correlate with the AVMA-COE Competencies. The AVMA-COE Competencies weakly correlated with scores earned in didactic courses of Years 1-3. AVMA-COE Competencies were internally consistent (mean r=.796) but only moderately correlated with performance on the NAVLE (mean r=.319). Low correlations between admissions criteria and outcomes indicate a need to reevaluate admission criteria as predictors of school success. If the NAVLE remains the primary discriminator for veterinary licensure (and the gateway to professional activity), then the AVMA-COE Competencies should be refined to better improve and reflect the NAVLE, or the NAVLE examination should change to reflect AVMA-COE Competencies. PMID:24152428

Roush, James K; Rush, Bonnie R; White, Brad J; Wilkerson, Melinda J

2014-01-01

2

7 CFR 1783.9 - What are the criteria for scoring applications?  

Science.gov (United States)

... What are the criteria for scoring applications? 1783.9... What are the criteria for scoring applications? (a...competitively based on the following scoring criteria: (1) Degree...points. (6) The evaluation methods for considering loan...

2010-01-01

3

50 CFR 91.23 - Scoring criteria for contest.  

Science.gov (United States)

50 ? Wildlife and Fisheries ? 6 ? 2010-10-01 ? 2010-10-01 ? false ? Scoring criteria for contest. ? 91.23 ? Section 91.23 ? Wildlife and Fisheries ? UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) ? MISCELLANEOUS PROVISIONS ? MIGRATORY BIRD HUNTING AND...

2010-10-01

4

Learning genetic epistasis using Bayesian network scoring criteria  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Gene-gene epistatic interactions likely play an important role in the genetic basis of many common diseases. Recently, machine-learning and data mining methods have been developed for learning epistatic relationships from data. A well-known combinatorial method that has been successfully applied for detecting epistasis is Multifactor Dimensionality Reduction (MDR. Jiang et al. created a combinatorial epistasis learning method called BNMBL to learn Bayesian network (BN epistatic models. They compared BNMBL to MDR using simulated data sets. Each of these data sets was generated from a model that associates two SNPs with a disease and includes 18 unrelated SNPs. For each data set, BNMBL and MDR were used to score all 2-SNP models, and BNMBL learned significantly more correct models. In real data sets, we ordinarily do not know the number of SNPs that influence phenotype. BNMBL may not perform as well if we also scored models containing more than two SNPs. Furthermore, a number of other BN scoring criteria have been developed. They may detect epistatic interactions even better than BNMBL. Although BNs are a promising tool for learning epistatic relationships from data, we cannot confidently use them in this domain until we determine which scoring criteria work best or even well when we try learning the correct model without knowledge of the number of SNPs in that model. Results We evaluated the performance of 22 BN scoring criteria using 28,000 simulated data sets and a real Alzheimer's GWAS data set. Our results were surprising in that the Bayesian scoring criterion with large values of a hyperparameter called ? performed best. This score performed better than other BN scoring criteria and MDR at recall using simulated data sets, at detecting the hardest-to-detect models using simulated data sets, and at substantiating previous results using the real Alzheimer's data set. Conclusions We conclude that representing epistatic interactions using BN models and scoring them using a BN scoring criterion holds promise for identifying epistatic genetic variants in data. In particular, the Bayesian scoring criterion with large values of a hyperparameter ? appears more promising than a number of alternatives.

Barmada M Michael

2011-03-01

5

Relationship between Praxis 1 Scores and SAT/ACT Scores: A Correlational Study  

Science.gov (United States)

The purpose of this paper is to test the premise that there is a significant correlation between Praxis1 scores and SAT scores among African American students who are applying for admission into the teacher education program. Data for the study included the Praxis 1 (reading, writing and math) scores and SAT (reading, writing and math) scores of…

Saravanabhavan, Sheila; Jones, Enid B.; Wilson, Carolyn H.

2005-01-01

6

Pre-Professional Skills Test Scores as College of Education Admission Criteria.  

Science.gov (United States)

Examined the validity of Pre-Professional Skills Test (PPST) scores as college admission criteria. Examination of teacher education program graduates' American College Test (ACT) scores, PPST subtest scores, PPST scores, undergraduate grade point averages (GPA), and student teaching ratings highlighted a concurrent relationship between…

Mikitovics, Audrey; Crehan, Kevin D.

2002-01-01

7

7 CFR 1703.126 - Criteria for scoring grant applications.  

Science.gov (United States)

...receive 0 points. (iii) The total score for this criterion will be based on the average score for all the end user sites included in...must receive a minimum of 20 points as an average score for all the end user sites under this...

2010-01-01

8

Examining Classification Criteria: A Comparison of Three Cut Score Methods  

Science.gov (United States)

This study compared 3 different methods of creating cut scores for a screening instrument, T scores, receiver operating characteristic curve (ROC) analysis, and the Rasch rating scale method (RSM), for use with the Behavioral and Emotional Screening System (BESS) Teacher Rating Scale for Children and Adolescents (Kamphaus & Reynolds, 2007). Using…

DiStefano, Christine; Morgan, Grant

2011-01-01

9

Criteria for genuine multiparticle quantum correlations  

International Nuclear Information System (INIS)

This thesis is devoted to different aspects of the detection and characterization of quantum correlations in multiparticle systems. These include the statistical verification of non-locality and entanglement in experiments, a versatile approach for the detection of genuine multipartite entanglement that will be applied to different classes of states and the characterization of entanglement using a multipartite hidden-variable theory. We start by investigating statistical effects on the confidence with which one can ensure that a multipartite state is non-local and therefore entangled. It turns out that for the standard photonic error model, the statistical significance of a non-locality test with comparably low violation, the so-called Mermin inequality, can exceed the significance of a test with high violation, namely of the Ardehali inequality. We also report about an experiment with four photons that verifies this behavior. Moreover, we also find that the range of white noise in which the Mermin inequality achieves a higher statistical significance grows exponentially with an increasing number of particles. Then, we pass on to the detection of genuine multipartite entanglement given the density matrix of a state. Using supersets of the sets of separable states, we introduce a criterion for genuine multipartite entanglement that can be implemented as a semidefinite program and test its performance on several example cases. Furthermore, this criterion naturally leads to an entanglement monotone that generalizes the bipartite negativity. Subsequently, the criterion is applied to the class of graph states. In this way, we obtain analytical construction methods for entanglement criteria, so-called entanglement witnesses, for many different graph states and an arbitrary number of qubits. These witnesses turn out to be strong, as their white noise tolerance converges to the maximum possible value, namely one, for a growing number of qubits. At the same time, the additional experimental effort in terms of settings to be measured, stays constant. Furthermore, as the criterion performs so well on graph states, we consider the question whether it can provide necessary and sufficient criteria for entanglement. We show that this is indeed the case for some special graph-diagonal states. In addition, our line of argument also provides deeper insights into the properties of our criterion and methods to construct biseparable graph-diagonal states. Finally, we turn to the characterization of quantum mechanical correlations given by the bipartite non-local model introduced by A. Leggett. We present different ways of extending this model to the case of many particles and also derive an inequality that shows the imcompatibility of such multipartite Leggett models with quantum mechanics. (author)

10

Correlation of admission criteria with dental school performance and attrition.  

Science.gov (United States)

This study was conducted to provide current information on the relationship between admission criteria and dental school performance, including the association of admission criteria and dental school outcomes such as remediation and attrition. Standard tests of bivariate association and multivariate regression models appropriate for continuous and discrete dependent variables were used to examine the relationship between multiple indicators of admission criteria and dental school performance for six recent classes at the University of Florida College of Dentistry (UFCD). The admission criteria included the undergraduate science grade point average (GPA), undergraduate non-science GPA, Dental Admissions Test (DAT) academic score, Perceptual Motor Aptitude Test (PMAT) score, and admission interview score. Measures of dental school performance were the National Dental Board Examination Part I and Part II (NB-I, NB-II) scores, yearly and final dental school GPA, and academic progress through the UFCD program. In general, most admission criteria were good bivariate indicators of dental school performance. Multivariate analyses indicated that students with higher undergraduate science GPAs and DAT academic scores were more likely to achieve higher NB-I and NB-II scores. The undergraduate science GPA and admission interview score were the most consistent determinants of dental school GPA. Students with lower undergraduate science GPAs, DAT academic scores, and PMAT scores were more likely to remediate, to repeat an academic year, or to be dismissed. Although bivariate differences were observed in several admission criteria of students who remediated one or more courses, repeated an academic year, or were dismissed only the undergraduate science GPA and the PMAT score were indicators of programmatic progress in the multivariate analysis. PMID:11936229

Sandow, Pamela L; Jones, Anne C; Peek, Chuck W; Courts, Frank J; Watson, Ronald E

2002-03-01

11

Diffuse Fatty Infiltration of the Liver: US Scoring System Correlated with CT and LFT  

International Nuclear Information System (INIS)

The present study was performed to estimate the accuracy of US examination in predicting the hepatic function in patients with diffuse fatty infiltration of the Liver. We compared the findings at US with the findings at CT and biochemical hepatic function test. US was performed by using 3.5MHz sector prove. We evaluated the US findings in terms or the degree of acoustic attenuation from the liver, the parenchymal echogenicity, the distinction of the portal vein wall, and the distinction of the diaphragm. Each parameter was graded into the numeric scores ranging from 0 to 2. The total US score was calculated from the scores of the four parameters. The total US score was compared with the difference in Hounsfield Units between the liver and spleen on nonenhanced CT images. The total US score was also compared with the aspartate(AST) and alanine transaminase(ALT) levels in peripheral blood. There was statistically significant correlation between the total US score and the difference in Hounsfield Unit between the liver and spleen on CT (r=0.7074, p<0.0001). When the total US score above 4 was considered as acriteria, the AST or ALT level were abnormal within the sensitivity of 90% and specificity of 60%. When the total US score above 5 was considered as a criteria, the sensitivity and specificity were 78% and 79%, respectively. In conclusion, US scoring system is useful in predicting the abnormal hepatic function in patients with diffuse fatty infiltration of the liver

12

Diffusion abnormality maps in demyelinating disease: Correlations with clinical scores  

International Nuclear Information System (INIS)

Background and purpose: Magnetic resonance imaging (MRI) has been explored as a noninvasive tool to assess pathology in multiple sclerosis (MS) patients. However, the correlation between classical MRI measures and physical disability is modest in MS. The diffusion tensor imaging (DTI) MRI technique holds particular promise in this regard. The present study shows brain regions where FA and individual diffusivities abnormalities are present and check their correlations with physical disability clinical scores. Methods: Eight patients and 12 matched healthy controls were recruited. The Multiple Sclerosis Functional Composite was administered. For MR-DTI acquisitions, a Genesis Signa 1.5T MR system, an EP/SE scanning sequence, 25 gradient directions were used. Results: Tract Based Spatial Statistics (TBSS) group comparisons showed reduced FA and increased individual diffusivities in several brain regions in patients. Significant correlations were found between FA and: EDSS, 9-HPT(NON)DOM and 25FW score; between ?2 and: P100 (r and l), 9-HPT(NON)DOM and 25FW; between ?3 and: 9-HPT(NON)DOM and 25FW score. Conclusions: Fractional anisotropy and individual radial diffusivities proved to be important markers of motor disabilities in MS patients when the disease duration mean and the disability scores values range are relatively high.

13

A Chronic Fatigue Syndrome (CFS) severity score based on case designation criteria  

Science.gov (United States)

Background: Chronic Fatigue Syndrome case designation criteria are scored as physicians’ subjective, nominal interpretations of patient fatigue, pain (headaches, myalgia, arthralgia, sore throat and lymph nodes), cognitive dysfunction, sleep and exertional exhaustion. Methods: Subjects self-reported symptoms using an anchored ordinal scale of 0 (no symptom), 1 (trivial complaints), 2 (mild), 3 (moderate), and 4 (severe). Fatigue of 3 or 4 distinguished “Fatigued” from “Not Fatigued” subjects. The sum of the 8(Sum8) ancillary criteria was tested as a proxy for fatigue. All subjects had history and physical examinations to exclude medical fatigue, and ensure categorization as healthy or CFS subjects. Results: Fatigued subjects were divided into CFS with ?4 symptoms or Chronic Idiopathic Fatigue (CIF) with ?3 symptoms. ROC of Sum8 for CFS and Not Fatigued subjects generated a threshold of 14 (specificity=0.934; sensitivity=0.928). CFS (n=256) and CIF (n=55) criteria were refined to include Sum8?14 and ?13, respectively. Not Fatigued subjects had highly skewed Sum8 responses. Healthy Controls (HC; n=269) were defined by fatigue?2 and Sum8?13. Those with Sum8?14 were defined as CFS–Like With Insufficient Fatigue Syndrome (CFSLWIFS; n=20). Sum8 and Fatigue were highly correlated (R2=0.977; Cronbach’s alpha=0.924) indicating an intimate relationship between symptom constructs. Cluster analysis suggested 4 clades each in CFS and HC. Translational utility was inferred from the clustering of proteomics from cerebrospinal fluid. Conclusions: Plotting Fatigue severity versus Sum8 produced an internally consistent classifying system. This is a necessary step for translating symptom profiles into fatigue phenotypes and their pathophysiological mechanisms. PMID:23390566

Baraniuk, James N; Adewuyi, Oluwatoyin; Merck, Samantha Jean; Ali, Mushtaq; Ravindran, Murugan K; Timbol, Christian R; Rayhan, Rakib; Zheng, Yin; Le, Uyenphuong; Esteitie, Rania; Petrie, Kristina N

2013-01-01

14

Automatic sleep scoring in normals and in individuals with neurodegenerative disorders according to new international sleep scoring criteria  

DEFF Research Database (Denmark)

Introduction: Reliable polysomnographic classification is the basis for evaluation of sleep disorders in neurological diseases. Aim: To develop a fully automatic sleep scoring algorithm on the basis of a reproduction of new international sleep scoring criteria from the American Academy of Sleep Medicine (AASM). Methods: A biomedical signal processing algorithm was developed, allowing for automatic sleep depth quantification of routine polysomnographic (PSG) recordings through feature extraction, supervised probabilistic Bayesian classification, and heuristic rule-based smoothing. The performance of the algorithm was tested using 28 manually classified day-night PSGs from 18 normal subjects and 10 patients with Parkinson's disease (PD) or multiple system atrophy (MSA). This led to quantification of automaticversus- manual epoch-by-epoch agreement rates for both normal and abnormal recordings. Results: Resulting average agreement rates were 87.7% (Cohen’s Kappa: 0.79) and 68.2%(Cohen’s Kappa: 0.26) in the normal and abnormal group, respectively. Based on an observed reliability of the manual scorer of 92.5% (Cohen’s Kappa: 0.87) in the normal group and 85.3% (Cohen’s Kappa: 0.73) in the abnormal group. Conclusion: The developed algorithm was capable of scoring normal sleep with an accuracy around the manual inter-scorer reliability, it failed in accurately scoring abnormal sleep as encountered for the PD/MSA patients, which is due to the abnormal micro- and macrostructure pattern in these patients.

SØrensen, Helge Bjarup Dissing

2010-01-01

15

Vitiligo Extent Tensity Index (VETI) score: a new definition, assessment and treatment evaluation criteria in vitiligo  

Science.gov (United States)

Although skin is the largest organ of the body, there are no standardized reproducible methods for assessing severity of many skin diseases. Due to lack of consensus, methods of assessment and inexistence of precise scoring system, there is no application for vitiligo estimation in real practice. In this paper the author describes VETI score as a new treatment evaluation criteria and severity assessment method for vitiligo. This new tool, as does the PASI score in psoriasis, may be able to produce a constant and reproducible number and to help clinical research on vitiligo patients. Additionally it has a potential to be a source of any computed application for researchers working on vitiligo patients.

Feily, Amir

2014-01-01

16

Do Severity Score and Skin Temperature Asymmetry Correlate with the Subjective Pain Score in the Patients with Complex Regional Pain Syndrome?  

Science.gov (United States)

Background The diagnostic criteria of complex regional pain syndrome (CRPS) have mainly focused on dichotomous (yes/no) categorization, which makes it difficult to compare the inter-patient's condition and to evaluate the intra-patient's subtle severity over the course of time. To overcome this limitation, many efforts have been made to create laboratory methods or scoring systems to reflect the severity of CRPS; measurement of the skin temperature asymmetry is one of the former, and the CRPS severity score (CSS) is one of the latter. However, there has been no study on the correlations among the CSS, temperature asymmetry and subjective pain score. The purpose of this study was to evaluate whether there is any correlation between the CSS, skin temperature asymmetry and subjective pain score. Methods Patients affected with CRPS in a unilateral limb were included in this study. After making a diagnosis of CRPS according to the Budapest criteria, the CSS and skin temperature difference between the affected and unaffected limb (?T) was measured in each patient. Finally, we conducted a correlation analysis among the CSS, ?T and visual analogue scale (VAS) score of the patients. Results A total of 42 patients were included in this study. There was no significant correlation between the ?T and VAS score (Spearman's rho = 0.066, P = 0.677). Also, the CSS and VAS score showed no significant correlation (Spearman's rho = 0.163, P = 0.303). Conclusions The ?T and CSS do not seem to reflect the degree of subjective pain in CRPS patients. PMID:25317283

Jeon, Seung Gyu; Choi, Eun Joo; Lee, Pyung Bok; Lee, Young Jae; Kim, Min Soo; Seo, Joung Hwa

2014-01-01

17

Estimates of genetic parameters for visual scores and their correlation with production and reproductive traits in Brahman cattle  

Directory of Open Access Journals (Sweden)

Full Text Available The objective of this study was to evaluate the association of visual scores of body structure, precocity and muscularity with production (body weight at 18 months and average daily gain and reproductive (scrotal circumference traits in Brahman cattle in order to determine the possible use of these scores as selection criteria to improve carcass quality. Covariance components were estimated by the restricted maximum likelihood method using an animal model that included contemporary group as fixed effect. A total of 1,116 observations of body structure, precocity and muscularity were used. Heritability was 0.39, 043 and 0.40 for body structure, precocity and muscularity, respectively. The genetic correlations were 0.79 between body structure and precocity, 0.87 between body structure and muscularity, and 0.91 between precocity and muscularity. The genetic correlations between visual scores and body weight at 18 months were positive (0.77, 0.57 and 0.59 for body structure, precocity and muscularity, respectively. Similar genetic correlations were observed between average daily gain and visual scores (0.60, 0.57 and 0.48, respectively, whereas the genetic correlations between scrotal circumference and these scores were low (0.13, 0.02, and 0.13. The results indicate that visual scores can be used as selection criteria in Brahman breeding programs. Favorable correlated responses should be seen in average daily gain and body weight at 18 months. However, no correlated response is expected for scrotal circumference.

Tássia Souza Bertipaglia

2012-06-01

18

Investigator feedback about the 2005 NIH diagnostic and scoring criteria for chronic GVHD.  

Science.gov (United States)

The 2005 National Institutes of Health (NIH) consensus criteria for chronic GVHD have set standards for reporting. Many questions, however, have arisen regarding their implementation and utilization. To identify perceived areas of controversy, we conducted an international survey on diagnosis and scoring of chronic GVHD. Agreement was observed for 50-83% of the 72 questions in 7 topic areas. There was agreement on the need for modifying criteria in six situations: two or more distinctive manifestations should be enough to diagnose chronic GVHD; symptoms that are not due to chronic GVHD should be scored differently; active disease and fixed deficits should be distinguished; a minimum threshold body surface area of hidebound skin involvement should be required for a skin score of 3; asymptomatic oral lichenoid changes should be considered a score 1; and lung biopsy should be unnecessary to diagnose chronic GVHD in a patient with bronchiolitis obliterans as the only manifestation. The survey also identified 26 points of controversy. Whenever possible, studies should be conducted to confirm the appropriateness of any revisions. In cases where data are not available, clarification of the NIH recommendations by consensus is necessary. This survey should inform future research in the field and revisions of the current consensus criteria. PMID:24464142

Inamoto, Y; Jagasia, M; Wood, W A; Pidala, J; Palmer, J; Khera, N; Weisdorf, D; Carpenter, P A; Flowers, M E D; Jacobsohn, D; Martin, P J; Lee, S J; Pavletic, S Z

2014-04-01

19

Prediction of kidney transplant outcome by donor quality scoring systems: expanded criteria donor and deceased donor score.  

Science.gov (United States)

Due to disparity between organ supply and demand, use of kidneys from suboptimal donors has become increasingly common. Several donor quality systems have been developed to identify kidneys with an increased risk for graft dysfunction and loss. The purpose of our study was to compare the utility of deceased donor score (DDS) and expanded criteria donor (ECD) status to predict kidney transplant outcomes in a single center. We analysed 280 deceased donor renal transplantation procedures, collecting data from the prospectively maintained institutional database. Kidney transplant outcome variable included delayed graft function, 1-year glomerular filtration rate (GFR1y), and death-censored graft loss (DCGL). Kidneys were obtained from marginal donors in 45.7% of transplant recipients by DDS and in 24.9% by ECD. DDS-defined marginal donors suffered delayed graft function (DGF) more frequently than nonmarginal donors (40.8% vs 25.0%; P = .006), whereas ECD did not develop DGF at a greater rate. GFR1Y was significantly worse among patients receiving kidneys from marginal donors: DDS 40.3 ± 12.9 vs 57.7 ± 19.4 mL/min/1.73 m(2) (P DDS (grade D) showed an independently worse death-censored graft survival hazard rate [HR] 2.661, 95% confidence interval [CI], 1.076-6.582; P = .034). DDS and ECD scoring systems are based on donor information available at the time of transplantation that predict 1-year graft function. Moreover in our center, DDS was better to predict DGF and death-censored graft survival than ECD. PMID:23146452

Arnau, A; Rodrigo, E; Miñambres, E; Ruiz, J C; Ballesteros, M A; Piñera, C; Fernandez-Fresnedo, G; Palomar, R; Arias, M

2012-11-01

20

Strategies in Comparison of Methods for Scoring Patient Management Problems: Use of External Criteria to Validate Scores.  

Science.gov (United States)

Whether alternative scoring strategies result in improved measurement properties of patient management problems (PMPs) was studied. Nine scoring systems (proficiency, efficiency, select, omit, data gathering, therapy, absolute, goal-oriented, and empiric expert score) were applied to 16 PMPs used in a certifying examination taken by 4,590…

Webster, G. D.; And Others

1988-01-01

 
 
 
 
21

Estimates of genetic parameters for visual scores and their correlation with production and reproductive traits in Brahman cattle  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in english The objective of this study was to evaluate the association of visual scores of body structure, precocity and muscularity with production (body weight at 18 months and average daily gain) and reproductive (scrotal circumference) traits in Brahman cattle in order to determine the possible use of thes [...] e scores as selection criteria to improve carcass quality. Covariance components were estimated by the restricted maximum likelihood method using an animal model that included contemporary group as fixed effect. A total of 1,116 observations of body structure, precocity and muscularity were used. Heritability was 0.39, 043 and 0.40 for body structure, precocity and muscularity, respectively. The genetic correlations were 0.79 between body structure and precocity, 0.87 between body structure and muscularity, and 0.91 between precocity and muscularity. The genetic correlations between visual scores and body weight at 18 months were positive (0.77, 0.57 and 0.59 for body structure, precocity and muscularity, respectively). Similar genetic correlations were observed between average daily gain and visual scores (0.60, 0.57 and 0.48, respectively), whereas the genetic correlations between scrotal circumference and these scores were low (0.13, 0.02, and 0.13). The results indicate that visual scores can be used as selection criteria in Brahman breeding programs. Favorable correlated responses should be seen in average daily gain and body weight at 18 months. However, no correlated response is expected for scrotal circumference.

Tássia Souza, Bertipaglia; Luis Orlando Duitama, Carreño; Carlos Henrique Cavallini, Machado; Cristiana, Andrighetto; Ricardo da, Fonseca.

22

Correlation-tensor criteria for genuine multiqubit entanglement  

International Nuclear Information System (INIS)

We present a development of a geometric approach to entanglement indicators. The method is applied to detect genuine multiqubit entanglement. The criteria are given in the form of nonlinear conditions imposed on correlation tensors. Thus they involve directly observable quantities, and in some cases require only few specific measurements to find multiqubit entanglement. The nonlinearity of each of the criteria allows detection of entanglement in wide classes of states. In contrast to entanglement witnesses, which in the space of Hermitian operators define a hyperplane, these conditions define a geometric figure encapsulating the nonfully entangled states within it.

23

Evaluation of utility in shoulder pathology: Correlating the American Shoulder and Elbow Surgeons and Constant scores to the EuroQoL  

Directory of Open Access Journals (Sweden)

Full Text Available AIM: To study whether health utility scores can be derived from shoulder-specific scores. METHODS: Authors investigated two questions: (1 do the American Shoulder and Elbow Surgeons (ASES score and the Constant score correlate with the EuroQoL (EQ-5D, a measure of health utility? (2 can the ASES and Constant scores be obtained from a complete study sample without bias? Thirty subjects with various shoulder diagnoses completed ASES, Constant, and EQ-5D instruments. Pearson correlations were calculated to assess the associations between EQ-5D score and ASES and Constant scores. RESULTS: The correlation between EQ-5D score and ASES score was 0.60 (P < 0.001; it was 0.54 for EQ-5D and Constant scores (P < 0.003. A multiple regression model containing ASES score, Constant score, age, and gender failed to adequately predict EQ-5D. Moreover, 25% of patients meeting the inclusion criteria did not complete the ASES questionnaire because they did not feel that specific questions, such as “do usual sport - list” and “throw ball overhand,” applied to them. CONCLUSION: Authors’ results do not support the use of the ASES and Constant scores in predicting EuroQol health utility values. However, the Constant score was more suitable for this patient population because all patients were able to complete it.

Blaine T Bafus

2012-01-01

24

The relationship between the ability to identify evaluation criteria and integrity test scores  

Digital Repository Infrastructure Vision for European Research (DRIVER)

It has been argued that applicants who have the ability to identify what kind of behavior is evaluated positively in a personnel selection situation can use this information to adapt their behavior accordingly. Although this idea has been tested for assessment centers and structured interviews, it has not been studied with regard to integrity tests (or other personality tests). Therefore, this study tested whether candidates’ ability to identify evaluation criteria (ATIC) correlates with th...

Ko?nig, Cornelius J.; Melchers, Klaus G.; MARTIN KLEINMANN; Richter, Gerald M.; UTE-CHRISTINE KLEHE

2006-01-01

25

Correlated Criteria in Decision Models: Recurrent Application of TOPSIS Method  

Directory of Open Access Journals (Sweden)

Full Text Available The purpose of multicriteria decision models is to help decision maker to evaluate each alternative and to rank them in descending order of performance. A problem can appear when the criteria are not independent. This study explores the effect of multicollinearity between criteria in decision making with the technique for order preference by similarity to ideal solution (TOPSIS and proposes an algorithm to resolve this problem. The algorithm was based on the application of the TOPSIS method several times until all the components are uncorrelated. The algorithm was applied on two examples from medical field to demonstrate its effectiveness. After we applied the purposed algorithm on two examples the index result from TOPSIS was equal correlated with all the criteria.

Cosmina Ioana BONDOR

2012-03-01

26

Correlation of the score for subjective pain with physical disability, clinical and radiographic scores in recent onset rheumatoid arthritis  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background To analyse the relationship between subjective pain score and other measures of clinical, radiographic and functional status; in particular Larsen radiographic scores and Health Assessment Questionnaire (HAQ; in patients with severe rheumatoid arthritis (RA with a disease duration of less than 3 years. Methods In this cross sectional study of 105 patients with RA (76 women, 29 men: mean age 50.93; mean disease duration 15.86 months; 71% rheumatoid factor positive subjective pain was assessed according to the Visual Analog Scale (VAS. Correlation coefficients between pain score and disease activity measures (patients' global assessment of disease by VAS, number of tender and swollen joints, morning stiffness, erythrocyte sedimentation rate [ESR], C-reactive protein [CRP] and titre of rheumatoid factor, radiographic evaluations (Larsen-Dale scores for radiographic damage of the small joints of the hands, wrist and feet, disability measures (health assessment questionnaire [HAQ], and demographic variables were calculated; hierarchical regression analysis was done with subjective pain score as the dependent variable. Results The Spearman's correlation coefficient comparing subjective pain and HAQ was 0.421 (p 0.05. In regression analysis, global assessment of disease by patients explained 32.8% of the variation in pain intensity score, morning stiffness 10.7%, CRP 4.0%, HAQ 3.8% and Larsen-Dale scores explained 2.1%; other variables were not significant in the model. Conclusions Pain scores of patients with early severe rheumatoid arthritis are correlated at higher levels with patients' global assessment of disease and with morning stiffness rather than with radiographic or other clinical variables such as number of tender and swollen joints.

Turiel Maurizio

2002-07-01

27

Diagnostic accuracy of modified kenneth jones scoring criteria (mkjsc) in confirmed cases of tuberculosis in children  

International Nuclear Information System (INIS)

Background: Tuberculosis (TB) is a granulomatous disease caused by Mycobacterium tuberculosis. The gold standard for the diagnosis of tuberculosis is detection of Mycobacterium tubercle bacilli. However, clinical scoring systems are most widely used for the diagnosis of TB in children. Objective: To determine the diagnostic accuracy of modified Kenneth Jones scoring criteria (MKJSC) in conformed cases of tuberculosis. Methodology: This cross-sectional comparative study was conducted in the department of Paediatrics, King Edward Medical University / Mayo Hospital, Lahore from January to June 2007. One hundred children below 15 years of age were enrolled. They were diagnosed as suspected cases of TB on the basis of fever and cough for more than 15 days. MKJSC was applied and each child was subjected to confirmatory test for TB. Results: There was an overall male preponderance of 54%. The mean age of study population was 1.8 +- 0.7 years. Out of 100 children, 66% were diagnosed as TB cases (23 with confirmatory tests and 43 with MKJSC of 5 or more). Sensitivity, specificity, positive and negative predictive value of MKJSC was 73.91%, 44.16%, 28.33%, and 85% respectively. Diagnostic accuracy of MKJSC was 51%. Conclusion: Present study does not support the hypothesis that MKJSC is a good alternative to confirmatory tests to diagnose tuberculosis in children. However, MKJSC is a simple tool, which can be applied to improve the case detection rate in the absence of sophisticated tests. (author)

28

7 CFR 1740.8 - Scoring criteria for the grant competition.  

Science.gov (United States)

...category. (1) The score for Economic Need is computed from the average of the National...percentage. The score is computed by multiplying the average eligibility percentage...negative result yields a score of zero. [(average NSLP eligibility...

2010-01-01

29

Automobile ride quality experiments correlated to iso-weighted criteria  

Science.gov (United States)

As part of an overall study to evaluate the usefulness of ride quality criteria for the design of improved ground transportation systems an experiment was conducted involving subjective and objective measurement of ride vibrations found in an automobile riding over roadways of various roughness. Correlation of the results led to some very significant relationships between passenger rating and ride accelerations. The latter were collapsed using a frequency-weighted root mean square measure of the random vibration. The results suggest the form of a design criterion giving the relationship between ride vibration and acceptable automobile ride quality. Further the ride criterion is expressed in terms that relate to rides with which most people are familiar. The design of the experiment, the ride vibration data acquisition, the concept of frequency weighting and the correlations found between subjective and objective measurements are presented.

Healey, A. J.; Young, R. K.; Smith, C. C.

1975-01-01

30

Ultrafast CT scoring system for assessing bronchopulmonary dysplasia. Reproducibility and clinical correlation  

International Nuclear Information System (INIS)

To evaluate the reproducibility of the Ultrafast CT (UFCT) scoring system and assess its usefulness in monitoring clinical severity in infants with bronchopulmonary dysplasia (BPD). UFCT scoring was done in 22 infants (15 boys and 7 girls aged 1 to 37 months) with BPD. A total of 258 lung fields were evaluated for the presence of hyperaeration, linear opacities, triangular subpleural opacities, and bronchovascular bundle distortion or thickening, and UFCT scores were given. Intraobserver and interobserver agreement and reproducibility of UFCT scores were statistically analyzed. In 12 patients, UFCT scores were linearly correlated with clinical severity scores based on respiratory dysfunction and complexity of care. 'Hyperaeration,' which was the most frequent (18 of 22, 81.8%) finding, showed high concordance (?=0.73, p<0.001, ?=0.59, p<0.001), and its UFCT scores significantly correlated with intraobserver and interobserver analyses (r=0.94, p<0.001, r=0.82, p<0.001, respectively). UFCT scores for hyperaeration significantly correlated with clinical scores (r=0.75, p<0.01), whereas those for the others did not. UFCT is useful for assessing BPD. Hyperaeration was the most common and reproducible finding, and its extent significantly correlated with clinical severity. (author)

31

Anomalous Diffusion and Long-range Correlations in the Score Evolution of the Game of Cricket  

CERN Document Server

We investigate the time evolution of the scores of the second most popular sport in world: the game of cricket. By analyzing the scores event-by-event of more than two thousand matches, we point out that the score dynamics is an anomalous diffusive process. Our analysis reveals that the variance of the process is described by a power-law dependence with a super-diffusive exponent, that the scores are statistically self-similar following a universal Gaussian distribution, and that there are long-range correlations in the score evolution. We employ a generalized Langevin equation with a power-law correlated noise that describe all the empirical findings very well. These observations suggest that competition among agents may be a mechanism leading to anomalous diffusion and long-range correlation.

Ribeiro, H V; Zeng, Xiao Han T

2012-01-01

32

Anomalous diffusion and long-range correlations in the score evolution of the game of cricket  

Science.gov (United States)

We investigate the time evolution of the scores of the second most popular sport in the world: the game of cricket. By analyzing, event by event, the scores of more than 2000 matches, we point out that the score dynamics is an anomalous diffusive process. Our analysis reveals that the variance of the process is described by a power-law dependence with a superdiffusive exponent, that the scores are statistically self-similar following a universal Gaussian distribution, and that there are long-range correlations in the score evolution. We employ a generalized Langevin equation with a power-law correlated noise that describes all the empirical findings very well. These observations suggest that competition among agents may be a mechanism leading to anomalous diffusion and long-range correlation.

Ribeiro, Haroldo V.; Mukherjee, Satyam; Zeng, Xiao Han T.

2012-08-01

33

7 CFR 1740.8 - Scoring criteria for the grant competition.  

Science.gov (United States)

...participation percentage. The score is computed by multiplying the average eligibility percentage...negative result yields a score of zero. [(average NSLP eligibility percentage...Critical Need evaluates factors not captured in the...

2010-01-01

34

Beyond Correlations: Usefulness of High School GPA and Test Scores in Making College Admissions Decisions  

Science.gov (United States)

Correlational evidence suggests that high school GPA is better than admission test scores in predicting first-year college GPA, although test scores have incremental predictive validity. The usefulness of a selection variable in making admission decisions depends in part on its predictive validity, but also on institutions' selectivity and…

Sawyer, Richard

2013-01-01

35

Correlations Between Chiropractic National Board (Part I) Scores and Basic Science Course Grades and Related Data.  

Science.gov (United States)

A study at one institution found significant correlations between students' scores on the National Board of Chiropractic Examiners test and academic achievement data. Results indicate that it is not always course subject matter that influences the relationship between course grade and board scores, but may instead be the ability to assimilate…

Wolfenberger, Virginia

1999-01-01

36

Correlation of problem-based learning facilitators' scores with student performance on written exams.  

Science.gov (United States)

Problem-based learning (PBL) is widely used in medical education. In some cases, facilitators assign a grade to reflect a student's performance in small-group sessions. In our PBL track, facilitators were asked to assess student knowledge base independent of their group participatory skills. To determine if facilitators' grades were correlated with student performance in written exams, a retrospective study of data from our PBL track was undertaken. Data from 156 students and 107 facilitators in six years of a PBL track at Penn State College of Medicine was analyzed by the Pearson correlation after pairing facilitator grades with written exam grades for each of the eight blocks of the curriculum. Exam reliability and validity were assessed by Cronbach's alpha and correlation with USMLE I board scores. The mean alpha was 0.549 +/- 0.221. The mean correlation with USMLE scores was 0.558 +/- 0.151. Facilitators' scores for knowledge were positively associated with students' exam grades. The corresponding significant Pearson correlation coefficients were between 0.342-0.622. However, the coefficients of determination showed that the correlation was not significant. Coefficients of determination showed that the knowledge scores explained only 12 to 39% of the variance in exam scores. Overestimation by facilitators was significantly (p exam score than for students in the top 25% of the class. On the basis of this study, we concluded that facilitator assessment of student knowledge base is not useful. PMID:11912333

Whitfield, Carol F; Xie, Sharon X

2002-01-01

37

Breast Cancer with Neoductgenesis: Histopathological Criteria and Its Correlation with Mammographic and Tumour Features  

Science.gov (United States)

Introduction. Breast cancer with mammographic casting type calcifications, high grade DCIS with an abnormal number of ducts, periductal desmoplastic reaction, lymphocyte infiltration, and tenascin-C (TN-C) overexpression has been proposed to represent a more aggressive form of breast cancer and has been denominated as breast cancer with neoductgenesis. We developed histopathological criteria for neoductgenesis in order to study reproducibility and correlation with other tumour markers. Methods. 74 cases of grades 2 and 3 DCIS, with or without an invasive component, were selected. A combined score of the degree(s) of concentration of ducts, lymphocyte infiltration, and periductal fibrosis was used to classify cases as showing neoductgenesis, or not. Diagnostic reproducibility, correlation with tumour markers, and mammographic features were studied. Results. Twenty-three of 74 cases were diagnosed with neoductgenesis. The kappa value between pathologists showed moderate reproducibility (0.50) (95% CI; 0.41–0.60). Neoductgenesis correlated significantly with malignant type microcalcifications and TN-C expression (P = 0.008 and 0.04) and with ER, PR, and HER2 status (P < 0.00001 for all three markers). Conclusions. We developed histological criteria for breast cancer with neoductgenesis. Neoductgenesis, by our applied histopathological definition was related to more aggressive tumour biology and malignant mammographic calcifications.

Sollie, Thomas; Pinder, Sarah E.; Amini, Rose-Marie; Blomqvist, Carl; Fjallskog, Marie-Louise; Christensson, Gunilla; Abdsaleh, Shahin; Warnberg, Fredrik

2014-01-01

38

7 CFR 1740.8 - Scoring criteria for the grant competition.  

Science.gov (United States)

...will be scored in three categories: the rurality of the applicant's core coverage...included in the application. (c) Rurality is a measure of the degree to which...since they represent fringe viewers. The Rurality score is computed as follows:...

2010-01-01

39

High resolution CT in children with cystic fibrosis: correlation with pulmonary functions and radiographic scores  

International Nuclear Information System (INIS)

Objective: To compare the high resolution CT (HRCT) scores of the Bhalla system with pulmonary function tests and radiographic and clinical points of the Shwachman-Kulczycki clinical scoring system. Methods: HRCT of the chest was obtained in 40 children to assess the role of HRCT in evaluating bronchopulmonary pathology in children with cystic fibrosis (CF). The HRCT severity scores of the Bhalla system were compared with chest radiographic and clinical points of the Shwachman-Kulczycki scoring system and pulmonary function tests. Only 14 of the patients older than 6 years cooperated with spirometry. Results: HRCT scores correlated well with radiographic points (r=0.80, P1 (r=0.66, P=0.01). Although radiographic points correlated significantly with FVC (r=0.61, P=0.02) and FEV1 (r=0.56, P=0.04), HRCT provides a more precise scoring than the chest X-ray. Conclusion: The HRCT scoring system may provide a sensitive method of monitoring pulmonary disease status and may replace the radiographic scoring in the Shwachman-Kulczycki system. It may be helpful especially in follow-up of small children too young to cooperate with spirometry

40

The Influence of Prior Experience on the Construction of Scoring Criteria for ESL Compostions: A Case Study  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Before a principled explanation of variability in raters' judgements of ESL compositions can be offered, the process of constructing scoring criteria and the manner in which prior experience enters this process must be analyzed. Therefore, utilizing protocol and intewiew data collected in the context of a comparative study, a case study will describe how one experienced rater dealt with the following operations while assessing a corpus of 60 TOEFL essays: establishing the purpose of assessmen...

Usman Erdosy, M.

2001-01-01

 
 
 
 
41

Correlation between the FINish diabetes risk score and the severity of coronary artery disease  

Directory of Open Access Journals (Sweden)

Full Text Available Background/Aim. The FINish Diabetes RIsk SCore (FINDRISC which includes age, body mass index (BMI, waist circumference, physical (in activity, diet, arterial hypertension, history of high glucose levels, and family history of diabetes, is of a great significance in identifying patients with impaired glucose tolerance and a 10-year risk assessment of developing type 2 diabetes in adults. Due to the fact that the FINDRISC score includes parameters which are risk factors for coronary artery disease (CAD, our aim was to determine a correlation between this score, and some of its parameters respectively, with the severity of angiographically verified CAD in patients with stable angina in two ways: according to the Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX score and the number of diseased coronary arteries. Methods. The study included 70 patients with stable angina consecutively admitted to the Clinic of Cardiology, Military Medical Academy, Belgrade. The FINDRISC score was calculated in all the patients immediately prior to angiography. Venous blood samples were collected and inflammatory markers [erythrocyte sedimentation rate (ESR, leucocytes, C-reactive protein (CRP, total cholesterol, HDL cholesterol, triglycerides and fasting glucose] determined. Coronary angiography was performed in order to determine the severity of coronary artery disease according to the SYNTAX score and the number of affected coronary vessels: 1-vessel, 2-vessel or 3-vessel disease (hemodynamically significant stenoses: more than 70% of the blood vessel lumen. The patients were divided into three groups regarding the FINDRISC score: group I: 5-11 points; group II: 12-16 points; group III: 17-22 points. Results. Out of 70 patients (52 men and 18 women enrolled in this study, 14 had normal coronary angiogram. There was a statistically significant positive correlation between the FINDRISC score and its parameters respectively (age, body mass index-BMI, waist circumference and the severity of CAD according to the SYNTAX score (p < 0.001 and the number of diseased coronary arteries (p < 0.001. The patients with higher FINDRISC score (groups II and III had more severe and extensive CAD according to the SYNTAX score than the group I. The odds ratio with 95% confidence intervals (CI between the group III and the group I was 5.143 (95% CI 1.299-20.360, p = 0.002 and between the group II and the group I 5.867 (95% CI 1.590- 21.525, p = 0.007. There were no differences in odds ratio for multivessel disease according to FINDRISC score between the group II and the group III [1.141; (95% CI 0.348-3.734. In the group I mean SYNTAX score was 5.18, and more than 70% of patients had normal coronary angiogram. In the group II mean SYNTAX score was 17.06, and more than 70% of patients had 2-vessel disease and 3- vessel disease, and in the group III mean SYNTAX score was 18.89, and 2-vessel and 3-vessel disease had 36.36% and 31.82% patients, respectively. In multiple regression analysis, where SYNTAX score was dependent variable, and age, BMI, waist circumference, FINDRISC score were independent variables, we found that only FINDRISC score was independent predictor of SYNTAX score. Conclusion. The obtained results suggest a statistically significant correlation between the FINDRISC score and its parameters (age, BMI, waist circumference and the severity of CAD according to the SYNTAX score and the number of diseased coronary arteries. The FINDRISC score may be useful in identifying patients at the high risk for coronary artery disease.

?uri? Predrag

2014-01-01

42

Correlated physical and mental health summary scores for the SF-36 and SF-12 Health Survey, V.1  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background The SF-36 and SF-12 summary scores were derived using an uncorrelated (orthogonal factor solution. We estimate SF-36 and SF-12 summary scores using a correlated (oblique physical and mental health factor model. Methods We administered the SF-36 to 7,093 patients who received medical care from an independent association of 48 physician groups in the western United States. Correlated physical health (PCSc and mental health (MCSc scores were constructed by multiplying each SF-36 scale z-score by its respective scoring coefficient from the obliquely rotated two factor solution. PCSc-12 and MCSc-12 scores were estimated using an approach similar to the one used to derive the original SF-12 summary scores. Results The estimated correlation between SF-36 PCSc and MCSc scores was 0.62. There were far fewer negative factor scoring coefficients for the oblique factor solution compared to the factor scoring coefficients produced by the standard orthogonal factor solution. Similar results were found for PCSc-12, and MCSc-12 summary scores. Conclusion Correlated physical and mental health summary scores for the SF-36 and SF-12 derived from an obliquely rotated factor solution should be used along with the uncorrelated summary scores. The new scoring algorithm can reduce inconsistent results between the SF-36 scale scores and physical and mental health summary scores reported in some prior studies. (Subscripts C = correlated and UC = uncorrelated

Cunningham William E

2007-09-01

43

Correlations in a Mozart's music score (K-73x) with palindromic and upside-down structure  

Science.gov (United States)

In this work, we study long-range correlations in a “Scherzo-Duetto di Mozart” score (K-73x) for two violins. This is a fascinating piece, as the second violin part is upside down on the same sheet below the first violin, and some parts are like a palindrome. Given such ingenious structure, it is expected the existence of long-range correlations in the score structure. In order to quantify long-range correlations, we considered the music score as a sequence of integer numbers, each of them corresponding to last common denominator units of note. By using detrended fluctuation analysis (DFA), correlations are quantified by means of the scaling exponent that reflects the type of correlations for a given distance between neighbors note. The following conclusions can be drawn from the analysis: (a) For about 10-25 neighbor note distances, correlations are similar to 1/f-noise. This is an interesting finding since it has been shown that pleasant sounds for humans display a behavior similar to 1/f noise. (b) As the neighbor note distance increases, the long-range correlations decays continuously. For some score sections, the music score behaves like non-correlated (i.e., purely random) noise. Summing up, the results show that the studied Mozart's score contains a certain degree of correlation for relatively small note distances, and becomes close to non-correlated behavior for long note distances. We considered also the sequence constructed by considering the distance between the simultaneously played notes of the two violins. Interestingly, for relatively small neighbor note distances, a scaling behavior similar to that found for individual violins is also displayed. In some sense, this is an expression of the specific structure (palindromes plus upside down construction) used by Mozart in the composition of this music score. Although we focused on a particular high-art music score, our results suggest that modern methods borrowed from statistical physics can be useful for the systematic study of music composition techniques.

Dagdug, Leonardo; Alvarez-Ramirez, Jose; Lopez, Carlos; Moreno, Rodolfo; Hernandez-Lemus, Enrique

2007-09-01

44

Lack of correlation between the mean tender point score and self-reported pain in fibromyalgia  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Objectives: To study the validity and nature of self-assessed symptoms among patients with fibromyalgia syndrome (FMS) and to compare our data with findings reported in the US. To determine whether tender point scores correlate with self-reported pain and other symptoms and to study the influence of disease duration. - Methods: Tender point scores were assessed in 113 consecutive patients with FMS. All patients completed 2 self-assessment questionnaires (an extended Campbell list, the Ens...

Jacobs, Johannes W. G.; Rasker, Johannes J.; Heide, Agnes; Boersma, Johannes; Blecourt, Alida C. E.; Griep, Eduard N.; Rijswijk, Martin H.; Bijlsma, Johannes W. J.

1996-01-01

45

MR imaging of acute pancreatitis: Correlation of abdominal wall edema with severity scores  

International Nuclear Information System (INIS)

Objective: To study MRI findings of abdominal wall edema (AWE) in acute pancreatitis as well as correlations between AWE and the severity of acute pancreatitis according to the MR severity index (MRSI) and the Acute Physiology And Chronic Healthy Evaluation III (APACHE III) scoring system. Materials and methods: A total of 160 patients with AP admitted to our institution between December 2009 and March 2011 were included in this study. MRI was performed within 48 h after admission. MRI findings of acute pancreatitis were noted, including AWE on the MRI. The abdominal wall area was divided into quarters, and each area involved was recorded as 1 point to score the severity of AWE. The severity of acute pancreatitis was studied using both the MRSI and the APACHE III scoring system. Spearman correlation of AWE with the MRSI and the APACHE III scoring system was analyzed. Results: In 160 patients with acute pancreatitis, 53.8% had AWE on MRI. The average AWE score was 1.2 ± 1.4 points. The prevalence of AWE was 30.5%, 64.5% and 100% in mild, moderate and severe AP, respectively, according to MRSI. AWE on MRI was correlated with MRSI scores (r = 0.441, p = 0.000). According to APACHE III scores, the averages were 2.0 ± 1.1 and 2.6 ± 1.1 points in mild AP and severe AP, respectively (P = 0.016). AWE was slightly correlated with the APACHE III scores (r = 0.222, p = 0.005). Conclusion: AWE on MRI in acute pancreatitis is common, which may be a supplementary indicator in determining the severity of AP.

46

MR imaging of acute pancreatitis: Correlation of abdominal wall edema with severity scores  

Energy Technology Data Exchange (ETDEWEB)

Objective: To study MRI findings of abdominal wall edema (AWE) in acute pancreatitis as well as correlations between AWE and the severity of acute pancreatitis according to the MR severity index (MRSI) and the Acute Physiology And Chronic Healthy Evaluation III (APACHE III) scoring system. Materials and methods: A total of 160 patients with AP admitted to our institution between December 2009 and March 2011 were included in this study. MRI was performed within 48 h after admission. MRI findings of acute pancreatitis were noted, including AWE on the MRI. The abdominal wall area was divided into quarters, and each area involved was recorded as 1 point to score the severity of AWE. The severity of acute pancreatitis was studied using both the MRSI and the APACHE III scoring system. Spearman correlation of AWE with the MRSI and the APACHE III scoring system was analyzed. Results: In 160 patients with acute pancreatitis, 53.8% had AWE on MRI. The average AWE score was 1.2 {+-} 1.4 points. The prevalence of AWE was 30.5%, 64.5% and 100% in mild, moderate and severe AP, respectively, according to MRSI. AWE on MRI was correlated with MRSI scores (r = 0.441, p = 0.000). According to APACHE III scores, the averages were 2.0 {+-} 1.1 and 2.6 {+-} 1.1 points in mild AP and severe AP, respectively (P = 0.016). AWE was slightly correlated with the APACHE III scores (r = 0.222, p = 0.005). Conclusion: AWE on MRI in acute pancreatitis is common, which may be a supplementary indicator in determining the severity of AP.

Yang, Ru, E-mail: yangru0904@163.com [Sichuan Key laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China); Jing, Zong Lin, E-mail: jzl325@163.com [Sichuan Key laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China); Zhang, Xiao Ming, E-mail: zhangxm@nsmc.edu.cn [Sichuan Key laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China); Tang, Wei, E-mail: tw-n-g-up@163.com [Sichuan Key laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China); Xiao, Bo, E-mail: xiaoboimaging@163.com [Sichuan Key laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China); Huang, Xiao Hua, E-mail: nc_hxh1966@yahoo.com.cn [Sichuan Key laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China); Yang, Lin, E-mail: llinyangmd@163.com [Sichuan Key laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China); Feng, Zhi Song, E-mail: fengzhisong@medmail.com.cn [Department of Gastroenterology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China)

2012-11-15

47

Correlation between academic performance and NBCE part I scores at a chiropractic college  

Science.gov (United States)

Objective This study investigates the association between pre-National Board assessments and National Board Part 1 scores (NBCE) at a chiropractic college. Methods A convenience sample of 24 students enrolled in the doctor of chiropractic degree program was recruited for the study. These were 6th and 7th quarter students who had registered to take NBCE in March 2011. Each student's class scores were computed and average numeric means score derived. Subject clusters that make up testable subject categories in NBCE also were computed to obtain a single numeric mean score. Pretests were administered in all areas tested in NBCE. Results were compared to the student's scores in NBCE using correlation and multiple linear regression for 14 predictors and one response variable (NBCE). Results Among the 14 correlations for 19 students (due to missing data when running the correlation matrix), six were moderate-to-strong and statistically significant. Two predictors qualified for multiple linear regression (where n = 22): mean anatomy and mean chemistry, both of which revealed similar regression coefficients. Conclusion Mean anatomy and mean chemistry scores were shown to be the best predictors of NBCE Part 1 results in this sample. PMID:23519085

Kenya, Amilliah W.M.; Kenya, Hope M.; Hart, John

2013-01-01

48

Correlation of HEDIS diabetes health plan score with utilization of diabetes medications.  

Science.gov (United States)

This study sought to determine the correlation between a health plan's Health Plan Employer Data and Information Set (HEDIS) score for glycated hemoglobin (HbA1c) control in patients with diabetes and its utilization of analog insulin, human insulin, and oral drug therapy as determined by the share of prescriptions of each therapy. Prescription volumes were tracked for four categories of diabetes drug therapy: (1) analog insulin, (2) human insulin, (3) single-source brand oral products, and (4) multisource generic oral products, for the three months ending January 2005 and January 2006 and matched to the 2004 and 2005 HEDIS scores. A correlation analysis conducted between the HbA1c-based HEDIS score and the prescription share of each drug category found a favorable and statistically significant (P brand and the multisource generic oral category prescription shares, although these correlations were found to be significant only for the single-source products in 2005. PMID:18405202

Weiss, Richard; Bazalo, Gary; Clark, Nathaniel; Forma, Felicia; Ingram, Garrett; Alemayehu, Berhanu

2007-10-01

49

Quality-of-care assessment by process and outcome scoring. Use of weighted algorithmic assessment criteria for evaluation of emergency room care of women with symptoms of urinary tract infection.  

Science.gov (United States)

Weighted process criteria based on chart review using an algorithmic method, and weighted outcome criteria based on a telephone interview with the patient, were used to assess the quality of emergency room care of women with symptoms of acute urinary tract infection. Outcomes at a municipal hospital were significantly better than those at an affiliated voluntary hospital. Process and outcome scores were positively correlated at both hospitals; the data suggest, but do not themselves adequately test, the hypothesis that the correlation is curvilinear and that there is a threshold process score below which a poor outcome is extremely likely. Our findings suggest that weighted algorithmic assessment criteria are a useful method for quality assessment and are consistent with the testable hypothesis that the greatest improvements in outcome may result from raising the quality of care from a poor to an adequate level rather than from an adequate to an optimal level. PMID:851312

Rubenstein, L; Mates, S; Sidel, V W

1977-05-01

50

Schizotypal perceptual aberrations of time: correlation between score, behavior and brain activity.  

Science.gov (United States)

A fundamental trait of the human self is its continuum experience of space and time. Perceptual aberrations of this spatial and temporal continuity is a major characteristic of schizophrenia spectrum disturbances--including schizophrenia, schizotypal personality disorder and schizotypy. We have previously found the classical Perceptual Aberration Scale (PAS) scores, related to body and space, to be positively correlated with both behavior and temporo-parietal activation in healthy participants performing a task involving self-projection in space. However, not much is known about the relationship between temporal perceptual aberration, behavior and brain activity. To this aim, we composed a temporal Perceptual Aberration Scale (tPAS) similar to the traditional PAS. Testing on 170 participants suggested similar performance for PAS and tPAS. We then correlated tPAS and PAS scores to participants' performance and neural activity in a task of self-projection in time. tPAS scores correlated positively with reaction times across task conditions, as did PAS scores. Evoked potential mapping and electrical neuroimaging showed self-projection in time to recruit a network of brain regions at the left anterior temporal cortex, right temporo-parietal junction, and occipito-temporal cortex, and duration of activation in this network positively correlated with tPAS and PAS scores. These data demonstrate that schizotypal perceptual aberrations of both time and space, as reflected by tPAS and PAS scores, are positively correlated with performance and brain activation during self-projection in time in healthy individuals along the schizophrenia spectrum. PMID:21267456

Arzy, Shahar; Mohr, Christine; Molnar-Szakacs, Istvan; Blanke, Olaf

2011-01-01

51

Correlated Criteria in Decision Models: Recurrent Application of TOPSIS Method  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The purpose of multicriteria decision models is to help decision maker to evaluate each alternative and to rank them in descending order of performance. A problem can appear when the criteria are not independent. This study explores the effect of multicollinearity between criteria in decision making with the technique for order preference by similarity to ideal solution (TOPSIS) and proposes an algorithm to resolve this problem. The algorithm was based on the application of the TOPSIS method ...

Bondor, Cosmina Ioana; Mures?an, Adriana

2012-01-01

52

THE INFLUENCE OF PRIOR EXPERIENCE ON THE CONSTRUCTION OF SCORING CRITERIA FOR ESL COMPOSITIONS: A CASE STUDY  

Directory of Open Access Journals (Sweden)

Full Text Available Before a principled explanation of variability in raters' judgements of ESL compositions can be offered, the process of constructing scoring criteria and the manner in which prior experience enters this process must be analyzed. Therefore, utilizing protocol and intewiew data collected in the context of a comparative study, a case study will describe how one experienced rater dealt with the following operations while assessing a corpus of 60 TOEFL essays: establishing the purpose of assessment, developing a reading strategy to deal with a corpus of essays, and collecting context-specific information. Within each operation, the influence of background variables such as teaching and assessment experience will be examined, particularly on determining what type of information to collect, and on articulating expectations concerning test takers, test scores and the textual qualities of essays. The results of the study will be used to specific directions for future research into explaining inter-rater variability.

M. Usman Erdosy

2001-12-01

53

MR spectroscopy of prostate cancer: correlation study of metabolic characters with Gleason score  

International Nuclear Information System (INIS)

Objective: Using magnetic resonance spectroscopy (MRS) to measure the metabolic ratio [(choline + creatine)/citrate, CC/C] of prostate cancer(PCa) and to probe the correlation between the value of CC/C ratio and Gleason score. Methods: Twenty-one cases of PCa proved by operation or systemic biopsy were examined by MRS. The prostate was divided into 6 regions (left/right bottom, middle and tip), and the CC/C value of each region was measured. After biopsy, all the puncture locations were marked and enrolled in one of the regions mentioned above and the Gleason scores were recorded. The ratio of CC/C measured by MRS was compared with Gleason score in the corresponding regions. Results: The average CC/C ratio of the 74 regions with PCa was 2.13±0.82, whereas the average CC/C ratio of the 52 regions without PCa was 0.59±0.20. The difference of CC/C value was statistically significant (t=7.72, P=0.00). The ratios of CC/C in the regions of PCa were correlated with Gleason score (r=0.659, P=0.01). In group 1 (Gleason score?7), the average CC/C ratio was 2.61±0.79. However, in group 2 (Gleasonscore <7) the average CC/C ratio was 1.69±0.59. There was statistically difference between the two groups (t=3.06, P=0.01). Conclusion: The metabolic ratio of CC/C is correlated to the Gleason score of PCa. MRS may be a useful method to evaluate the malignancy of PCa noninvasively. (authors)

54

Inflammation-based scores do not predict post-transplant recurrence of hepatocellular carcinoma in patients within milan criteria.  

Science.gov (United States)

Increased preoperative inflammation scores, such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and inflammation-based index (IBI) have been related to post-transplant HCC recurrence. We evaluated the association between inflammation-based scores (NLR, PLR, IBI) and post-LT HCC recurrence as well as tumor necrosis after transarterial embolization. 150 consecutive patients who underwent transplantation for HCC within the Milan criteria between 1996 and 2010 were included; data regarding inflammatory markers, patient and tumor characteristics were analyzed. NLR, PLR, and IBI were not significantly associated with post-LT HCC recurrence or worse overall survival. Increased NLR and PLR were associated with complete tumor necrosis in the subset of patients who received preoperative transarterial embolization (P?PLR were associated with better response to TAE, as this was recorded histologically in the explanted liver. Histological fulfillment of the Milan criteria and absence of neoadjuvant transarterial treatment were significantly associated with post-LT HCC recurrence. Liver Transpl 20:1327-1335, 2014. © 2014 AASLD. PMID:25088400

Parisi, Ioanna; Tsochatzis, Emmanuel; Wijewantha, Hasitha; Rodríguez-Perálvarez, Manuel; De Luca, Laura; Manousou, Pinelopi; Fatourou, Evangelia; Pieri, Giulia; Papastergiou, Vassilios; Davies, Neil; Yu, Dominic; Luong, TuVinh; Dhillon, Amar Paul; Thorburn, Douglas; Patch, David; O'Beirne, James; Meyer, Tim; Burroughs, Andrew K

2014-11-01

55

Score functions and statistical criteria to manage intensive follow up in business surveys  

Directory of Open Access Journals (Sweden)

Full Text Available In the frame of a statistical survey, the identification of non respondent units thatshould be object with priority of a reminder action (Intensive Follow Up - IFU, with the aimto produce enough good estimates, represents a relevant, but quite not deeply analysed methodological aspect. In this context, we propose and compare some score functions -that can be all reconnected to a generalised function – evaluating how much is dangerousthe exclusion from calculations of each unit. Moreover, we evaluate and compare somecriteria aimed at identifying IFU units by means of suitable statistical tests or thresholdsderived by parametric or non parametric methods. A comparative empirical applicationon a panel of Italian retail trade businesses has been carried out and commented.

Roberto Gismondi

2013-05-01

56

MRI bone oedema scores are higher in the arthritis mutilans form of psoriatic arthritis and correlate with high radiographic scores for joint damage  

DEFF Research Database (Denmark)

INTRODUCTION: The aim of this study was to investigate the magnetic resonance imaging (MRI) features of bone disease in the arthritis mutilans (AM) form of psoriatic arthritis (PsA). METHODS: Twenty-eight patients with erosive PsA were enrolled (median disease duration of 14 years). Using x-rays of both hands and feet, 11 patients were classified as AM and 17 as non-AM (erosive psoriatic arthritis without bone lysis)by two observers. MRI scans (1.5T) of the dominant hand (wrist and fingers scanned separately) were obtained using standard contrast-enhanced T1-weighted and fat-saturated T2-weighted sequences. Scans were scored separately by two readers for bone erosion, oedema and proliferation using a PsA MRI scoring system. X-rays were scored for erosions and joint space narrowing. RESULTS: On MRI, 1013 bones were scored by both readers. Reliability for scoring erosions and bone oedema was high (intraclass correlation coefficients = 0.80 and 0.77 respectively) but only fair for bone proliferation (intraclass correlation coefficient = 0.42). MRI erosion scores were higher in AM patients (53.0 versus 15.0, p = 0.004) as were bone oedema and proliferation scores (14.7 versus 10.0, p = 0.056 and 3.6 versus 0.7, p = 0.003 respectively). MRI bone oedema scores correlated with MRI erosion scores and X-ray erosion and joint space narrowing scores (r = 0.65, p = 0.0002 for all) but not the disease activity score 28-C reactive protein (DAS28CRP) or pain scores. CONCLUSIONS: In this patient group with PsA, MRI bone oedema, erosion and proliferation were all more severe in the AM-form. Bone oedema scores did not correlate with disease activity measures but were closely associated with X-ray joint damage scores. These results suggest that MRI bone oedema may be a pre-erosive feature and that bone damage may not be coupled with joint inflammation in PsA.

Tan, Yu M; Østergaard, Mikkel

2009-01-01

57

Correlation between Air Trapping Scoring and Spirometric Findings in Sulfur Mustard Exposed Patients  

Directory of Open Access Journals (Sweden)

Full Text Available Background/Objective: Pulmonary complains (acute and chronic are known complications of exposure to sulfur mustard gas that for evaluation of them multiple paraclinical methods as HRCT and spirometry were used. HRCT is preferred to plain chest X-ray and conventional CT scan because better detection of both parenchymal and airway abnormalities such as bronchectasia and air trapping. Expiratory HRCT is considered as the imaging modality of choice for evaluation of air trapping."nPatients and Methods: In this study we reviewed medical records of 36 patients with documented exposure to sulfur mustard in Iran-Iraq war in order to evaluate correlation between air trapping scoring and spirometric findings."nResults: In all HRCTs air trapping was present with score ranging from 2 to 18 and mean (±SD was 7.5 (4.2 . Nineteen cases had score over than six that suggest bronchiolitis obliterans. Spirometric indices as patient FEV1, FVC, FEV1/FVC, MMEF and their percentage to mean values were obtained. We found no correlation between air trapping scoring and spirometric parameters according to r and p-values obtained by SPSS software. "nConclusion: HRCT can be diagnosed bronchiolitis obliterans in earlier stages than spirometry.

A. Adibi

2008-01-01

58

Correlation between psychometric test scores and learning tying of surgical reef knots.  

Digital Repository Infrastructure Vision for European Research (DRIVER)

We have investigated the correlation between the scores attained on a computerised psychometric test, measuring psychomotor aptitude and learning tying of a surgical reef knot. Fifteen surgical trainees performed a test of psychomotor aptitude (ADTRACK 2) from the MICROPAT testing system. They then performed a simple test of their ability to tie a surgical reef knot and were assessed by a panel of experts prior to embarking on a standardised course of instruction and practice session. The kno...

Dashfield, A. K.; Lambert, A. W.; Campbell, J. K.; Wilkins, D. C.

2001-01-01

59

Correlation between semiquantitative myocardial perfusion score and absolute myocardial flow in 13N-ammonia PET  

International Nuclear Information System (INIS)

13N-ammonia is a well known radiopharmaceutical for the measurement of a myocardial blood flow (MBF) non-invasively using PET-CT. In this study, we investigated a correlation between MBF obtained from dynamic imaging and myocardial perfusion score (MPS) obtained from static imaging for usefulness of cardiac PET study. Twelve patients (11 males, 1 female, 57.9 ± 8.6 years old) with suspicious coronary artery disease underwent PET-CT scan. Dynamic scans (6 min: 5 sec X 12, 10 sec X 6, 20 sec X 3, and 30 sec X 6) were initiated simultaneously with bolus injection of 11 MBq/kg 13N-ammonia to acquire rest and stress image. Gating image was acquired during 13 minutes continuously. Nine-segment model (4 basal walls, 4 mid walls, and apex) was used for a measurement of MBF. Time activity curve of input function and myocardium was extracted from ROI methods in 9 regions for quantification. The MPS were evaluated using quantitative analysis software. To compare between 20-segment model and 9-segment model, 6 basal segments were excluded and averaged segmental scores were used. There are weak correlation between MBF (rest, 0.18-2.38 ml/min/g; stress, 0.40-4.95 ml/min/g) and MPS (rest 22-91%, stress, 14-90%), however the correlation coefficient between corrected MBF and MPS in rest state was higher than stress state (rest r=0.59; stress r=0.80). As a thickening increased, correlation between MBF and MPS also showed good correlation at each segments. Correctood correlation at each segments. Corrected and translated MPS as its characteristics using 13N-ammonia showed good correlation with absolute MBF measured by dynamic image in this study. Therefore, we showed MPS is one of good indices which reflect MBF. We anticipate PET-CT could be used as useful tool for evaluation of myocardial function in nuclear cardiac study

60

Correlations of visual scores, carcass traits, feed efficiency and retail product yield in Nellore cattle  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in english The growing use of visual scores (VS) and ultrasound (US) for carcass evaluation in breeding programs, calls for a knowledge of the relationships between these traits and other relevant characteristics, such as feed efficiency and production of commercial cuts. The objective of this study was to eva [...] luate correlations between body visual scores and carcass traits identified by ultrasound (US) and feed efficiency (FE), carcass weight (HCW), dressing percentage (DP) and retail product yield (RPY) in beef cattle. Nellore cattle (male), 42 non-castrated [NCAST] and 44 castrated [CAST]) were evaluated by both VS and US, at the postweaning (15-month old) and finishing phases (21-month old). Visual scores of conformation (C), precocity (P) and muscling (M) were assessed and the backfat thickness (UBFT), rump fat thickness (URFT) and ribeye area (UREA) were measured by ultrasound. Gain-to-feed (G:F) ratio and residual feed intake (RFI) were measured in feedlot. Hot carcass weight, DP and RPY were determined at harvest. Non-castrated cattle had greater HCW and RPY but lower UBFT and URFT than CAST. Postweaning VS and US were poorly correlated with FE in both sexual conditions. Finishing VS were negatively correlated with G:F in CAST and finishing URFT was negatively correlated with RPY in NCAST. The relationship of VS and US with feed efficiency and meat yield is affected by age at the date of evaluation and by castration. Feed efficiency is not related to the yield of meat cuts in Nellore cattle

Paulo Henrique, Cancian; Rodrigo da Costa, Gomes; Fernando Ricardo, Manicardi; Andrea Cristina, Ianni; Marina de Nadai, Bonin; Paulo Roberto, Leme; Saulo da Luz e, Silva.

 
 
 
 
61

Correlations of visual scores, carcass traits, feed efficiency and retail product yield in Nellore cattle  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in english The growing use of visual scores (VS) and ultrasound (US) for carcass evaluation in breeding programs, calls for a knowledge of the relationships between these traits and other relevant characteristics, such as feed efficiency and production of commercial cuts. The objective of this study was to eva [...] luate correlations between body visual scores and carcass traits identified by ultrasound (US) and feed efficiency (FE), carcass weight (HCW), dressing percentage (DP) and retail product yield (RPY) in beef cattle. Nellore cattle (male), 42 non-castrated [NCAST] and 44 castrated [CAST]) were evaluated by both VS and US, at the postweaning (15-month old) and finishing phases (21-month old). Visual scores of conformation (C), precocity (P) and muscling (M) were assessed and the backfat thickness (UBFT), rump fat thickness (URFT) and ribeye area (UREA) were measured by ultrasound. Gain-to-feed (G:F) ratio and residual feed intake (RFI) were measured in feedlot. Hot carcass weight, DP and RPY were determined at harvest. Non-castrated cattle had greater HCW and RPY but lower UBFT and URFT than CAST. Postweaning VS and US were poorly correlated with FE in both sexual conditions. Finishing VS were negatively correlated with G:F in CAST and finishing URFT was negatively correlated with RPY in NCAST. The relationship of VS and US with feed efficiency and meat yield is affected by age at the date of evaluation and by castration. Feed efficiency is not related to the yield of meat cuts in Nellore cattle

Paulo Henrique, Cancian; Rodrigo da Costa, Gomes; Fernando Ricardo, Manicardi; Andrea Cristina, Ianni; Marina de Nadai, Bonin; Paulo Roberto, Leme; Saulo da Luz e, Silva.

2014-02-01

62

Massa ventricular e critérios eletrocardiográficos de hipertrofia: avaliação de um novo escore / Ventricular mass and electrocardiographic criteria of hypertrophy: evaluation of new score  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese FUNDAMENTO: A hipertrofia ventricular esquerda (HVE) é um importante e independente fator de risco cardiovascular. Inexistem, no Brasil, estudos desenhados para testar a eficácia do eletrocardiograma (ECG) no diagnóstico desse grave processo patológico. OBJETIVO: Avaliar um novo escore eletrocardiog [...] ráfico para diagnóstico de HVE pelo ECG: soma da maior amplitude da onda S com a maior da onda R no plano horizontal, multiplicando-se o resultado pela duração do QRS [(S+R) X QRS)] e comparando-o com os critérios eletrocardiográficos clássicos. MÉTODOS: Foram analisados os ecocardiogramas e ECG de 1.204 pacientes hipertensos em tratamento ambulatorial. Avaliou-se o índice de massa do ventrículo esquerdo (IMVE) pelo ecocardiograma, firmando-se o diagnóstico de HVE quando > 96 g/m² para mulheres e > 116 g/m² para homens. No ECG analisaram-se quatro critérios clássicos de HVE, além do novo escore a ser testado. RESULTADOS: Todos os índices estudados tiveram correlação estatisticamente significativa com a massa calculada do ventrículo esquerdo (VE). Porém, o novo escore foi o que apresentou maior correlação (r = 0,564). Os outros critérios apresentaram as seguintes correlações: Romhilt-Estes (r = 0,464); Sokolow-Lyon (r = 0,419); Cornell voltagem (r = 0,377); Cornell duração (r = 0,444). Para avaliação da acurácia do índice testado, utilizou-se o ponto de corte de 2,80 mm.s. Com esse valor foram obtidas as seguintes cifras para sensibilidade e especificidade: 35,2% e 88,7%, respectivamente. CONCLUSÃO: Todos os critérios eletrocardiográficos para avaliação da massa do VE apresentaram baixa sensibilidade. O novo escore foi o que apresentou melhor correlação com o IMVE em relação aos outros avaliados. Abstract in english BACKGROUND: The left ventricular hypertrophy (LVH) is an important and independent cardiovascular risk factor. There is a scarcity of studies in Brazil designed to test the efficacy of the electrocardiogram (ECG) in the diagnosis of this important pathological process. OBJECTIVE: To evaluate a new e [...] lectrocardiographic score for the diagnosis of LVH by ECG: the sum of the highest amplitude of the S wave and the highest amplitude of the R wave on the horizontal plane, multiplied by the result of the QRS duration [(S+R) X QRS)] and comparing it with the classic electrocardiographic criteria. METHODS: The echocardiograms and ECG of 1,204 hypertensive patients receiving outpatient care were evaluated. The left ventricular mass index (LVMI) was assessed by the echocardiogram, with a diagnosis of LVH when the LVMI was > 96 g/m² for women and > 116 g/m² for men. Four classic criteria of LVH were analyzed at the ECG, in addition to the new score to be tested. RESULTS: In general, the studied ECG-LVH criteria showed significant statistical correlation to the echocardiographic LVMI. The (R+S) X QRS index, using 2.80 mm.s as the cutoff value, provided test accuracy regarding sensibility and specificity of 35.2% and 88.71%, respectively, representing the best correlation to LVMI (r=0.564) when compared to the other indexes: Romhilt-Estes (r=0.464); Sokolow-Lyon (r=0.419); Cornell voltage (r=0.377); Cornell product r=0.444). CONCLUSION: All the electrocardiographic criteria used for the assessment of the LV mass presented low sensitivity. The new score presented the best correlation with LVMI when compared to the other indexes.

Cléber do Lago, Mazzaro; Francisco de Assis, Costa; Maria Teresa Nogueira, Bombig; Bráulio, Luna Filho; Ângelo Amato Vincenzo de, Paola; Antonio Carlos de Camargo, Carvalho; William da, Costa; Francisco Antonio Helfenstein, Fonseca; Rui Manoel dos Santos, Póvoa.

63

Correlation of high-molecular cytokeratin in tissue of prostatic cancer with gleason score and PSA  

Directory of Open Access Journals (Sweden)

Full Text Available The absence of basal cell layer of prostatic acini containing high-molecular cytokeratin, which is immunohistochemically detected by monoclonal antibody 34?E12, is an essential diagnostic characteristic of prostatic cancer. The absence of im munohistochemical reaction in 3 or more pseudo glandular structures of prostatic tissue indicates malignant process. The percentage of immunohistochemically completely negative glandular structures was determined by semiquantitative measurement in tissue specimens obtained by TRUS biopsy of the prostate, and it was correlated with serum PSA concentration and Gleason score. The increase of percentage of glandular prostatic formations completely negative to high-molecular cytokeratin detected by 34?E12 led to simultaneous rise of mean value of Gleason prostatic cancer score (p<0.001 as well as the average serum PSA concentration in subjects (p<0.05.

Markovi?-Lipkovski J.

2005-01-01

64

Using IQ discrepancy scores to examine the neural correlates of specific cognitive abilities.  

Science.gov (United States)

The underlying neural determinants of general intelligence have been studied intensively, and seem to derive from the anatomical and functional characteristics of a frontoparietal network. Little is known, however, about the underlying neural correlates of domain-specific cognitive abilities, the other factors hypothesized to explain individual performance on intelligence tests. Previous preliminary studies have suggested that spatially distinct neural structures do not support domain-specific cognitive abilities. To test whether differences between abilities that affect performance on verbal and performance tasks derive instead from the morphological features of a single anatomical network, we assessed in two independent samples of healthy human participants (N=83 and N=58; age range, 5-57 years) the correlation of cortical thickness with the magnitude of the verbal intelligence quotient (VIQ)-performance intelligence quotient (PIQ) discrepancy. We operationalized the VIQ-PIQ discrepancy by regressing VIQ onto PIQ (VIQ-regressed-on-PIQ score), and by regressing PIQ onto VIQ (PIQ-regressed-on-VIQ score). In both samples, a progressively thinner cortical mantle in anterior and posterior regions bilaterally was associated with progressively greater (more positive) VIQ-regressed-on-PIQ scores. A progressively thicker cortical mantle in anterior and posterior regions bilaterally was associated with progressively greater (more positive) PIQ-regressed-on-VIQ scores. Variation in cortical thickness in these regions accounted for a large portion of the overall variance in magnitude of the VIQ-PIQ discrepancy. The degree of hemispheric asymmetry in cortical thickness accounted for a much smaller but statistically significant portion of variance in VIQ-PIQ discrepancy. PMID:23986248

Margolis, Amy; Bansal, Ravi; Hao, Xuejun; Algermissen, Molly; Erickson, Cole; Klahr, Kristin W; Naglieri, Jack A; Peterson, Bradley S

2013-08-28

65

Correlation of a quantitative videocapillaroscopic score with the development of digital skin ulcers in scleroderma patients  

Directory of Open Access Journals (Sweden)

Full Text Available Background: Systemic sclerosis (SSc is an autoimmune disease characterized by fibrosis of the skin and visceral organs. The microangiopathy is early detectable in the course of the disease by nailfold videocapillaroscopy (NVC, a non-invasive technique with a high diagnostic value. Objective: Aim of our study was to evaluate the feasibility of a quantitative score and its correlation with the digital skin ulcers, which frequently complicate SSc microangiopathy. Methods: We retrospectively analysed the NVC of 65 SSc patients, performed by 200x videocapillaroscopy connected to image analyse software (Videocap; DS MediGroup, Milan, Italy. The analysis of NVC images included: total number of capillaries in the distal row (N, maximum diameter (D and number of giant capillaries (M, M/N ratio and percentage of M, presence/absence of micro-haemorrhages and tortuosity. Results: 21/65 SSc patients experienced digital ulcers within three months after the NVC examination. The N, D, M/N, and percentage of M significantly correlated with the appearance of ischemic ulcers. A multiple regression analysis showed a statistically significant correlation for N, M/N and D, while sensitivity and specificity of these parameters were unsatisfactory. A capillaroscopic score, according to the formula D·M/N2, showed a high specificity and sensibility (93.2% and 85.7% respectively; area under ROC curve: 0.918 to predict the appearance of digital ulcers. Conclusions: This capillaroscopic score may represent a feasible and simple tool in SSc patients’ assessment. The routinely use of this parameter might permit to recognize and to preventively treat SSc patients at high risk to develop digital ulcers.

A. Antonelli

2011-09-01

66

Estimates of genetic parameters for visual scores and their correlation with production and reproductive traits in Brahman cattle  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The objective of this study was to evaluate the association of visual scores of body structure, precocity and muscularity with production (body weight at 18 months and average daily gain) and reproductive (scrotal circumference) traits in Brahman cattle in order to determine the possible use of these scores as selection criteria to improve carcass quality. Covariance components were estimated by the restricted maximum likelihood method using an animal model that included contemporary group as...

Tássia Souza Bertipaglia; Luis Orlando Duitama Carreño; Carlos Henrique Cavallini Machado; Cristiana Andrighetto; Ricardo da Fonseca

2012-01-01

67

Validity of the Oral Behaviours Checklist: correlations between OBC scores and intensity of facial pain.  

Science.gov (United States)

The first purpose of this study was to translate the Oral Behaviours Checklist (OBC) into Dutch and to examine its psychometric properties. The second purpose was to examine the correlations between scores on the OBC and facial pain, while controlling for the possible confounding effects of psychosocial factors, such as stress, depression, somatisation and anxiety. The OBC was translated, following the international RDC/TMD consortium guidelines. Its psychometric properties were examined by assessing the test-retest reliability and concurrent validity [correlations between the OBC and the previously developed Oral Parafunctions Questionnaire (OPQ)]. Participants were 155 patients with TMD (77% female; mean age and s.d. = 43.6 and 14.4 years). The translation of the OBC into Dutch proceeded satisfactorily. The psychometric properties of the Dutch OBC were good; test-retest reliability was excellent (ICC = 0.86, P OBC and OPQ was high (r = 0.757, P < 0.001), while the correlations between individual items ranged from 0.389 to 0.892 (P < 0.001). Similar to previous Dutch studies using the OPQ, no significant correlation was found between oral parafunctions and facial pain (r = 0.069, P = 0.892). No significant correlations could be found between oral parafunctional behaviours and facial pain. PMID:24274580

van der Meulen, M J; Lobbezoo, F; Aartman, I H A; Naeije, M

2014-02-01

68

Evaluation of cytogenetic damage in workers exposed to microwave radiation of GEM radar using new criteria in scoring micronucleus test  

International Nuclear Information System (INIS)

The cytokinesis-block micronucleus assay is one of the standard cytogenetic tools employed in the assessment of chromosomal damage subsequent to the exposure to genotoxic/cytotoxic agents on human cells. Within the frame of this study, the cytokinesis-block micronucleus assay was used to assess the baseline cytogenetic damage in binuclear lymphocytes in workers occupationally exposed to microwave radiation of GEM radar by virtue of measuring the frequency of micronuclei, nucleoplasmic bridges and nuclear buds. Microwave radiation of GEM radar equipment acts within microwave field of 10 ?W/cm2 to 10 mW/cm2 and frequency range of 1.5 GHz to 10.9 GHz that has contradictory cytogenetic effect on human cells and DNA molecule. For that reason we used new criteria in scoring micronucleus assay that allows us to measure nucleoplasmic bridges and nuclear buds in addition to micronucleus frequency for more accurate effect on possible damage on the level of the cells. Parameters of the micronucleus test were studied in workers occupationally exposed to microwave radiation of GEM radar and in corresponding unexposed control subjects. It was found that in the subjects who were occupationally exposed to microwave radiation, the levels of micronuclei increased and showed interindividual variations. In addition, new parameters that were measured; nucleoplasmic bridges and nuclear buds, were detected in exposed group in compare to control group that did not showompare to control group that did not shown this type of damage. Differences between mean group values were statistically significant (P<0.05). Our study indicates that micronucleus assay is a very useful tool in the assessment of cytogenetic damage of individuals exposed to microwave radiation of GEM radar equipment. On the basis of the micronucleus frequency and frequencies of nucleoplasmic bridges and nuclear buds, the micronucleus technique with an easy and short-term application and with an easy scoring can be used for detection of damage induced by this type of radiation. (author)

69

A Clinical Prediction Score in Addition to WHO Criteria for Anti-Retroviral Treatment Failure in Resource-Limited Settings - Experience from Lesotho  

Science.gov (United States)

Objective To assess the positive predictive value (PPV) of a clinical score for viral failure among patients fulfilling the WHO-criteria for anti-retroviral treatment (ART) failure in rural Lesotho. Methods Patients fulfilling clinical and/or immunological WHO failure-criteria were enrolled. The score includes the following predictors: Prior ART exposure (1 point), CD4-count below baseline (1), 25% and 50% drop from peak CD4-count (1 and 2), hemoglobin drop?1 g/dL (1), CD4 count40 copies (95%CI: 84–100), and of 90% to detect a VL?5000 copies (70–97). Within the score, adherence<95%, CD4-count<100/µl and papular pruritic eruption were the strongest single predictors. Among 47 patients failing, 8 (17%) died before or within 4 weeks after being switched. Overall mortality was 4 (20%) among those with score?5 and 4 (5%) if score<5 (OR 4.3; 95%CI: 0.96–18.84, p?=?0.057). Conclusion A score?5 among patients fulfilling WHO-criteria had a PPV of 100% for a detectable VL and 90% for viral failure. In settings without regular access to VL-testing, this PPV may be considered high enough to switch this patient-group to second-line treatment without confirmatory VL-test. PMID:23118910

Labhardt, Niklaus Daniel; Lejone, Thabo; Setoko, Matse'liso; Poka, Matalenyane; Ehmer, Jochen; Pfeiffer, Karolin; Kiuvu, Patrice Zinga; Lynen, Lutgarde

2012-01-01

70

Correlacao do EuroSCORE com o surgimento de lesao renal aguda pos-operatoria em cirurgia cardiaca / Correlation of the EuroSCORE with the onset of postoperative acute kidney injury in cardiac surgery  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese OBJETIVO: Verificar se há correlação entre valores do EuroSCORE e o risco de desenvolver lesão renal aguda em pacientes submetidos à cirurgia cardíaca. MÉTODOS: Estudo retrospectivo, realizado em hospital terciário, em pacientes consecutivos com indicação para abordagem cirúrgica cardíaca (val [...] vares, isquêmicas e congênitas) entre outubro de 2010 a julho de 2011. RESULTADOS: Foram avaliados cem pacientes. Destes, seis foram excluídos (cinco por doença renal ou terapia dialítica prévias e um devido a informações incompletas no prontuário médico). As principais indicações cirúrgicas foram revascularização miocárdica em 55 pacientes (58,5% dos casos) e trocas valvares em 28 pacientes (29,8%). Conforme o EuroSCORE, 55 pacientes foram classificados como risco alto (58,5%), 27 pacientes como risco médio (28,7%) e 12 pacientes como risco baixo (12,8%). No período pós-operatório, 31 pacientes (33%) evoluíram com aumento da creatinina sérica (18 (19,1%) RIFLE "R"; 7 (7,4%) RIFLE "I"; e 6 (6,5%) RIFLE "F"). Na amostra considerada de alto risco pelos critérios do EuroSCORE, 24 pacientes (43,6%) apresentaram comprometimento renal agudo. Nos pacientes classificados como de médio e de baixo risco, ocorreu lesão renal aguda em 18,5 e 16,6% dos casos, respectivamente. A associação entre a estratificação de risco (baixo, médio e alto) do EuroSCORE e o escore do RIFLE pós-operatório foi estatisticamente significante (p=0,03). CONCLUSÃO: Na população estudada, houve correlação estatisticamente significante entre o EuroSCORE e o risco de desenvolvimento de lesão renal aguda no pós-operatório de cirurgia cardíaca. Abstract in english OBJECTIVE: The objective of this study was to assess the correlation between the European System for Cardiac Operative Risk Evaluation (EuroSCORE) score and the risk of developing acute kidney injury in cardiac surgery patients. METHODS: This retrospective study was conducted at a tertiary hos [...] pital on consecutive cardiac surgery patients (e.g., valvular, ischemic and congenital heart diseases) between October 2010 and July 2011. RESULTS: One hundred patients were assessed. Among the 100 patients, six were excluded, including five because of prior kidney disease or dialysis therapy and one because of incomplete medical records. The primary surgical indications were myocardial revascularization in 55 patients (58.5% of cases) and valve replacement in 28 patients (29.8%). According to the EuroSCORE, 55 patients were classified as high risk (58.5%), 27 patients as medium risk (28.7%) and 12 patients as low risk (12.8%). In the postoperative period, patients were classified with the Risk, Injury, Failure, Loss and End-stage kidney disease (RIFLE) score. Among the 31 patients (33%) who displayed an increase in serum creatinine, 18 patients (19.1%) were classified as RIFLE "R" (risk), seven patients (7.4%) were classified as RIFLE "I" (injury) and six patients (6.5%) were classified as RIFLE "F" (failure). Among the patients who were considered to be high risk according to the EuroSCORE criteria, 24 patients (43.6%) showed acute kidney injury. Among the patients who were classified as medium or low risk, acute kidney injury occurred in 18.5 and 16.6% of the cases, respectively. The correlations between risk stratification (low, medium and high) and the EuroSCORE and postoperative RIFLE scores were statistically significant (p=0.03). CONCLUSION: In the studied population, there was a statistically significant correlation between the EuroSCORE and the risk of developing acute kidney injury in the postoperative period after cardiac surgery.

Edmilson Bastos de, Moura; Saint-Clair Gomes, Bernardes Neto; Fabio Ferreira, Amorim; Renato Camargo, Viscardi.

71

Correlacao do EuroSCORE com o surgimento de lesao renal aguda pos-operatoria em cirurgia cardiaca / Correlation of the EuroSCORE with the onset of postoperative acute kidney injury in cardiac surgery  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese OBJETIVO: Verificar se há correlação entre valores do EuroSCORE e o risco de desenvolver lesão renal aguda em pacientes submetidos à cirurgia cardíaca. MÉTODOS: Estudo retrospectivo, realizado em hospital terciário, em pacientes consecutivos com indicação para abordagem cirúrgica cardíaca (val [...] vares, isquêmicas e congênitas) entre outubro de 2010 a julho de 2011. RESULTADOS: Foram avaliados cem pacientes. Destes, seis foram excluídos (cinco por doença renal ou terapia dialítica prévias e um devido a informações incompletas no prontuário médico). As principais indicações cirúrgicas foram revascularização miocárdica em 55 pacientes (58,5% dos casos) e trocas valvares em 28 pacientes (29,8%). Conforme o EuroSCORE, 55 pacientes foram classificados como risco alto (58,5%), 27 pacientes como risco médio (28,7%) e 12 pacientes como risco baixo (12,8%). No período pós-operatório, 31 pacientes (33%) evoluíram com aumento da creatinina sérica (18 (19,1%) RIFLE "R"; 7 (7,4%) RIFLE "I"; e 6 (6,5%) RIFLE "F"). Na amostra considerada de alto risco pelos critérios do EuroSCORE, 24 pacientes (43,6%) apresentaram comprometimento renal agudo. Nos pacientes classificados como de médio e de baixo risco, ocorreu lesão renal aguda em 18,5 e 16,6% dos casos, respectivamente. A associação entre a estratificação de risco (baixo, médio e alto) do EuroSCORE e o escore do RIFLE pós-operatório foi estatisticamente significante (p=0,03). CONCLUSÃO: Na população estudada, houve correlação estatisticamente significante entre o EuroSCORE e o risco de desenvolvimento de lesão renal aguda no pós-operatório de cirurgia cardíaca. Abstract in english OBJECTIVE: The objective of this study was to assess the correlation between the European System for Cardiac Operative Risk Evaluation (EuroSCORE) score and the risk of developing acute kidney injury in cardiac surgery patients. METHODS: This retrospective study was conducted at a tertiary hos [...] pital on consecutive cardiac surgery patients (e.g., valvular, ischemic and congenital heart diseases) between October 2010 and July 2011. RESULTS: One hundred patients were assessed. Among the 100 patients, six were excluded, including five because of prior kidney disease or dialysis therapy and one because of incomplete medical records. The primary surgical indications were myocardial revascularization in 55 patients (58.5% of cases) and valve replacement in 28 patients (29.8%). According to the EuroSCORE, 55 patients were classified as high risk (58.5%), 27 patients as medium risk (28.7%) and 12 patients as low risk (12.8%). In the postoperative period, patients were classified with the Risk, Injury, Failure, Loss and End-stage kidney disease (RIFLE) score. Among the 31 patients (33%) who displayed an increase in serum creatinine, 18 patients (19.1%) were classified as RIFLE "R" (risk), seven patients (7.4%) were classified as RIFLE "I" (injury) and six patients (6.5%) were classified as RIFLE "F" (failure). Among the patients who were considered to be high risk according to the EuroSCORE criteria, 24 patients (43.6%) showed acute kidney injury. Among the patients who were classified as medium or low risk, acute kidney injury occurred in 18.5 and 16.6% of the cases, respectively. The correlations between risk stratification (low, medium and high) and the EuroSCORE and postoperative RIFLE scores were statistically significant (p=0.03). CONCLUSION: In the studied population, there was a statistically significant correlation between the EuroSCORE and the risk of developing acute kidney injury in the postoperative period after cardiac surgery.

Edmilson Bastos de, Moura; Saint-Clair Gomes, Bernardes Neto; Fabio Ferreira, Amorim; Renato Camargo, Viscardi.

2013-09-01

72

Clinical Criteria for Airway Assessment: Correlations with Laryngoscopy and Endotracheal Intubation Conditions  

Directory of Open Access Journals (Sweden)

Full Text Available Difficult intubation, inadequate ventilation and esophageal intubation are the principal causes of death or brain damage related to airway manipulation. The objective of this cross-sectional study was to correlate a preanesthetic evaluation that may be capable of predicting a difficult intubation with the conditions encountered at laryngoscopy and endotracheal intubation. Eighty-one patients submitted to general anesthesia were evaluated at a preanesthetic consultation according to the modified Mallampati classification, the Wilson score and the American Society of Anesthesiologists (ASA difficult airway algorithm. Findings were then correlated with the Cormack-Lehane classification and with the number of attempts at endotracheal intubation. No statistically significant correlations were found between the patients’ Mallampati classification and their Cormack-Lehane grade or between the Mallampati classification and the number of attempts required to achieve endotracheal intubation. Laryngoscopy proved difficult in four patients and in all of these cases the Wilson score had been indicative of a possibly difficult airway, highlighting its good predicting sensitivity. However, the specificity of this test was low, since another 24 patients had the same Wilson score but were classified as Cormack-Lehane I/II. Moreover, two patients who had a Wilson score ? 4 were also classified as Cormack-Lehane grade I/II. The study concluded that the Wilson score, although seldom used in clinical practice, is a highly sensitive predictor of a difficult airway; its specificity, however, is low.

Gustavo Henrique S. Wanderley

2013-08-01

73

Correlación entre score de calcio coronario, esteatosis hepática y síndrome metabólico / Correlation between coronary calcium score, hepatic steatosis and metabolic syndrome  

Scientific Electronic Library Online (English)

Full Text Available SciELO Chile | Language: Spanish Abstract in spanish Objetivos. Demostrar la correlación que existe entre presencia o no de enfermedad coronaria establecida (medida a través del índice de Agatston) y esteatosis hepática en los segmentos visualizados del hígado al momento de realizar el score de calcio. Material y Métodos. Estudio retrospectivo que inc [...] luyó 229 pacientes con factores de riesgo para enfermedad coronaria a los que se les realizó tomografía computada multicorte de arterias coronarias o score de calcio. Se evaluó la presencia de enfermedad ateromatosa en arterias coronarias y aorta torácica y atenuación hepática en los segmentos visualizados del hígado. El análisis estadístico incluyó modelos de regresión lineal, estudio por asociación de múltiples variables y modelo CART. Resultados. 229 pacientes, 78% de sexo masculino y 22% femenino, con edad promedio 56 años. Se demostró asociación estadísticamente significativa entre mayor nivel de score de calcio y menor atenuación hepática, en pacientes de mayor edad y sexo masculino. Se logró definir dos tipos de pacientes con score de calcio elevado, un grupo con hipertensión arterial - esteatosis hepática y otro grupo con hipertensión arterial y diabetes tipo 2; los pacientes solamente obesos no tenían mayores niveles de score de calcio. Conclusiones. Existe asociación entre ateromatosis calcificada y esteatosis hepática. Los pacientes con esteatosis hepática como parte de un síndrome metabólico, tienen mayor riesgo de ateroesclerosis. Puede ser útil incorporar la evaluación de esteatosis hepática en la estratificación de riesgo cardiovascular. Abstract in english Objectives. To demonstrate the correlation between the presence or absence of established coronary disease (as measured by the Agatston index) and hepatic steatosis visualized in liver segments when calculating calcium score. Material and Methods. Retrospective study that included229 patients with r [...] isk factors for coronary disease who underwent multislice computed tomography of coronary arteries or calcium score. We evaluated the presence of atherosclerotic disease in coronary arteries and thoracic aorta and liver attenuation in visualized liver segments. Statistical analysis included linear regression models, association studies of multiple variables and CARTmodel. Results. 229 patients, 78% male, average age 56 years. It values statistically significant association was found between higher levels of calcium score and lower hepatic attenuation in older patients and males. We were to define two types of patients with high calcium score, a group with hypertension - hepatic steatosis and another groups with hypertension and type 2 diabetes; patients that were only obese did not have higher levels of calcium score. Conclusions. A relationship exists between calcified atheromatosis disease and hepatics steatosis. Patients with hepatics steatosis as part of a metabolic syndrome are at increased risk of atherosclerosis. It may be useful to incorporate the assessment of hepatics steatosis in cardiovascular risk stratification.

Karina, Hermosilla M; Daniela, Pivcevic C; Julia, Alegria B; Claudio, Silva F.

74

Big Macs and Eigenfactor Scores: Don't Let Correlation Coefficients Fool You  

CERN Document Server

The Eigenfactor Metrics provide an alternative way of evaluating scholarly journals based on an iterative ranking procedure analogous to Google's PageRank algorithm. These metrics have recently been adopted by Thomson-Reuters and are listed alongside the Impact Factor in the Journal Citation Reports. But do these metrics differ sufficiently so as to be a useful addition to the bibliometric toolbox? Davis (2008) has argued otherwise, based on his finding of a 0.95 correlation coefficient between Eigenfactor score and total citations for a sample of journals in the field of medicine. This conclusion is mistaken; here we illustrate the basic statistical fallacy to which Davis succumbed. We provide a complete analysis of the 2006 Journal Citation Reports and demonstrate that there are important differences between the information provided by the Eigenfactor Metrics and that provided by Impact Factor and Total Citations.

West, Jevin; Bergstrom, Carl

2009-01-01

75

Modified Chrispin-Norman chest radiography score for cystic fibrosis: observer agreement and correlation with lung function  

Energy Technology Data Exchange (ETDEWEB)

To test observer agreement and two strategies for possible improvement (consensus meeting and reference images) for the modified Chrispin-Norman score for children with cystic fibrosis (CF). Before and after a consensus meeting and after developing reference images three observers scored sets of 25 chest radiographs from children with CF. Observer agreement was tested for line, ring, mottled and large soft shadows, for overinflation and for the composite modified Chrispin-Norman score. Correlation with lung function was assessed. Before the consensus meeting agreement between observers 1 and 2 was moderate-good, but with observer 3 agreement was poor-fair. Scores correlated significantly with spirometry for observers 1 and 2 (-0.72correlation with lung function, but agreement for the modified Chrispin-Norman score did not improve further. Consensus meetings and reference images improve among-observer agreement for the modified Chrispin-Norman score, but good agreement was not achieved among all observers for the modified Chrispin-Norman score and for bronchial line and ring shadows. (orig.)

Jong, P.A. de; Achterberg, J.A.; Kessels, O.A.M.; Beek, F.J. [Department of Radiology, University Medical Center Utrecht, Wilhelmina Children' s Hospital, Utrecht (Netherlands); Ginneken, B. van; Hogeweg, L. [Radboud University Nijmegen Medical Centre, Department of Radiology, Nijmegen (Netherlands); Image Sciences Institute, University Medical Center Utrecht, Utrecht (Netherlands); Terheggen-Lagro, S.W.J. [University Medical Center Utrecht, Wilhelmina Children' s Hospital, Department of Pediatric Pulmonology, Utrecht (Netherlands)

2011-04-15

76

Modified Chrispin-Norman chest radiography score for cystic fibrosis: observer agreement and correlation with lung function  

International Nuclear Information System (INIS)

To test observer agreement and two strategies for possible improvement (consensus meeting and reference images) for the modified Chrispin-Norman score for children with cystic fibrosis (CF). Before and after a consensus meeting and after developing reference images three observers scored sets of 25 chest radiographs from children with CF. Observer agreement was tested for line, ring, mottled and large soft shadows, for overinflation and for the composite modified Chrispin-Norman score. Correlation with lung function was assessed. Before the consensus meeting agreement between observers 1 and 2 was moderate-good, but with observer 3 agreement was poor-fair. Scores correlated significantly with spirometry for observers 1 and 2 (-0.72< R<-0.42, P < 0.05), but not for observer 3. Agreement with observer 3 improved after the consensus meeting. Reference images improved agreement for overinflation and mottled and large shadows and correlation with lung function, but agreement for the modified Chrispin-Norman score did not improve further. Consensus meetings and reference images improve among-observer agreement for the modified Chrispin-Norman score, but good agreement was not achieved among all observers for the modified Chrispin-Norman score and for bronchial line and ring shadows. (orig.)

77

Factors that correlate with the U.S. Medical Licensure Examination Step-2 scores in a diverse medical student population.  

Science.gov (United States)

OBJECTIVE: To assess factors that correlate with performance on U.S. Medical Licensure Examination (USMLE) Step-2 examination. Our hypothesis was that demographic factors, faculty assessments and other standardized test scores will correlate with students' performance on USMLE Step 2. STUDY DESIGN: A comparison of standardized examinations and demographic factors with USMLE Step-2 scores as the outcome variable was accomplished using the educational records of 171 medical students. RESULTS: Mean USMLE Step 2, USMLE Step 1, NBME-OB/GYN and MCAT scores, respectively, were 190.63, 194.53, 67.47 and 24.03. Positive correlations of USMLE Step 2 were: USMLE Step-1 scores (r=0.681, p=0.000); MCAT scores (r=0.524, p=0.000); NBME-OB/GYN scores (r=0.614, p=0.000); year of OB/GYN rotation (r=0.432, p=0.000); faculty grades (r=0.400, p=0.000); undergraduate GPA (r=0.287, p=0.000); and science GPA (r=0.255, p=0.002). Negative correlations of USMLE Step 2 were students' increasing age (r=-0.405, p=0.000), increasing number of MCAT attempts (r=-0.182, p=0.000) and increasing number of NBME-OB/GYN attempts (r=-0.310, p=0.000). There was no correlation with gender or race. Logistic regression analysis showed that a failing NBME-OB/GYN score (p=0.008), failing USMLE Step-1 score (p=0.01), failing faculty grade (p=0.029) and multiple MCAT attempts (p=0.033) independently increased the risk of failing USMLE Step 2. CONCLUSIONS: Premedical test-taking abilities (MCAT scores), results of preclinical standardized tests (USMLE Step 1) and performance on clinical rotations (NBME-OB/GYN score and faculty grade) correlate significantly with USMLE scores. These findings may assist educators in selecting medical students at risk of performing poorly on the USMLE Step-2 examinations. PMID:16296216

Ogunyemi, Dotun; Taylor-Harris, De Shawn

2005-01-01

78

Impact of white matter hyperintensities scoring method on correlations with clinical data: the LADIS study  

DEFF Research Database (Denmark)

BACKGROUND AND PURPOSE: White matter hyperintensities (WMH) are associated with decline in cognition, gait, mood, and urinary continence. Associations may depend on the method used for measuring WMH. We investigated the ability of different WMH scoring methods to detect differences in WMH load between groups with and without symptoms. METHODS: We used data of 618 independently living elderly with WMH collected in the Leukoaraiosis And DISability (LADIS) study. Subjects with and without symptoms of depression, gait disturbances, urinary incontinence, and memory decline were compared with respect to WMH load measured qualitatively using 3 widely used visual rating scales (Fazekas, Scheltens, and Age-Related White Matter Changes scales) and quantitatively with a semiautomated volumetric technique and an automatic lesion count. Statistical significance between groups was assessed with the chi2 and Mann-Whitney tests. In addition, the punctate and confluent lesion type with comparable WMH volume were compared with respect to the clinical data using Student t test and chi2 test. Direct comparison of visual ratings with volumetry was done using curve fitting. RESULTS: Visual and volumetric assessment detected differences in WMH between groups with respect to gait disturbances and age. WMH volume measurement was more sensitive than visual scores with respect to memory symptoms. Number of lesions nor lesion type correlated with any of the clinical data. For all rating scales, a clear but nonlinear relationship was established with WMH volume. CONCLUSIONS: Visual rating scales display ceiling effects and poor discrimination of absolute lesion volumes. Consequently, they may be less sensitive in differentiating clinical groups

van Straaten, EC; Fazekas, F

2006-01-01

79

Detection of coronary calcium during standard chest computed tomography correlates with multi-detector computed tomography coronary artery calcium score.  

Science.gov (United States)

The correlation between formal coronary artery calcium scoring (CACS) determined by multi-detector CT (MDCT) and the presence of coronary calcium on standard non-gated CT chest examinations was evaluated. In 163 consecutive healthy participants, we performed screening same-day standard non-gated, non-enhanced CT chest exams followed by high-resolution, ECG-synchronized MDCT exams for CACS. For the standard CT examinations, a scoring system (Weston score, range 0-12) was developed assigning a score (0-3) for each coronary vessel including the left main trunk. Overall, 30% and 39% of patients had CAC on standard CT and MDCT exams, respectively (P = 0.13). CAC on standard CT was highly correlated to the Agatston CACS on the MDCT (Spearman correlation coefficient 0.83, P exam was associated with a very low CACS (mean Agatston 0.5, range 0-19). A Weston score >2 identified a CACS > 100 with an area under the curve of 0.976, sensitivity of 100%, and specificity of 85%. A Weston score >7 identified a CACS > 400 with an area under the curve of 0.991, sensitivity of 100%, specificity of 98%. The intra-observer variability was low as was the inter-observer variability between a cardiac specialized radiologist and a non-specialized reader. A visual coronary artery scoring system on standard, non-gated CT correlates well with traditional methods for CACS. Further, a non-expert cardiac radiologist performed equally well to a cardiac expert. This information suggests that a visual scoring system, at least in a descriptive manner can be utilized for a general statement about coronary artery calcification seen on standard CT imaging to guide clinicians in risk stratification. PMID:21833776

Kirsch, Jacobo; Buitrago, Ivan; Mohammed, Tan-Lucien H; Gao, Tianming; Asher, Craig R; Novaro, Gian M

2012-06-01

80

Chesapeake Bay habitat criteria scores and the distribution of submersed aquatic vegetation in the tidal Potomac River and Potomac Estuary, 1983-1997  

Science.gov (United States)

The Chesapeake Bay Program has identified habitat requirements for the restoration of submersed aquatic vegetation (SAV) in the Chesapeake Bay estuary and tidal reaches of contributing river systems conditioned on the salinity regime of a specific location. The tidal Potomac River and Potomac Estuary is an important component of the Chesapeake Bay system to which these requirements can be applied. The SAV habitat requirements are formulated as threshold criteria that certain critical water-quality characteristics must satisfy during the SAV growing season. A multivariate scoring system based on these criteria was developed in order to synopsize water quality conditions during the 1983-1997 SAV growing seasons. Chesapeake Bay habitat criteria scores are displayed relative to annual SAV coverage for each Potomac River and Potomac Estuary segment. It is seen that although there is some correspondence in the inter-annual expansion or contraction of SAV coverage and compliance with Chesapeake Bay SAV habitat criteria, individual criteria provide neither necessary nor sufficient conditions to explain inter-annual dynamics of SAV coverage, especially in the Potomac Estuary.

Landwehr, J. M; Reel, J. T.; Rybicki, N. B.; Ruhl, H. A.; Carter, Virginia

1999-01-01

 
 
 
 
81

Correlation between the Gleason Scores of Needle Biopsies and Radical Prostatectomy Specimens.  

Directory of Open Access Journals (Sweden)

Full Text Available Background: The Gleason score has been shown to offer important information withregard to prognosis and therapy for patients with adenocarcinoma of theprostate gland. In this study, Gleason scores, as determined by 18-gauge coreneedle biopsies, were compared with both Gleason scores and the pathologicalstaging of corresponding radical prostatectomy specimens.Methods: Records of 78 consecutive patients undergoing a radical retropubic prostatectomybetween 1998 and 2002 were reviewed. In total, 78 patients wereenrolled, all of whom had been diagnosed with adenocarcinoma by transrectalneedle biopsies using an 18-gauge automated spring-loaded biopsy gun.Results: Grading errors were greatest with well-differentiated tumors. The accuracywas 6 (23% for Gleason scores of 2-4 on needle biopsy. Of the 36 evaluablepatients with Gleason scores of 5-7 on needle biopsy, 28 (78% were gradedcorrectly. All of the Gleason scores of 8-10 on needle biopsy were gradedcorrectly. Eighteen (33% of 54 patients with a biopsy Gleason score of < 7had their cancer upgraded to above 7. Tumors in 6 patients (60% with both aGleason score < 7 on the needle biopsy and a Gleason score of 7 for theprostatectomy specimen were confined to the prostate.Conclusion: The potential for grading errors is greatest with well-differentiated tumorsand in patients with a Gleason score of < 7 on the needle biopsy. Predictionsusing Gleason scores are sufficiently accurate to warrant its use with all needlebiopsies, recognizing that the potential for grading errors is greatest withwell-differentiated tumors.

Biing-Yir Shen

2003-12-01

82

Increased expression of EphA1 protein in prostate cancers correlates with high Gleason score  

Science.gov (United States)

The erythropoietin-producing hepatocellular (Eph) family of receptor tyrosine kinases regulates a multitude of physiological and pathological processes. EphA1 is the first member of Eph superfamily and is involved in carcinogenesis. The aim of this study was to investigate the expression of EphA1 in prostate cancers cell lines and the tissues, then explore the correlation with the clinicopathologic parameters. The EphA1 transcript expression in prostate cancer cell lines was detected by Quantitative real-time PCR. The expression of EphA1 protein in 138 prostate cancer tissue samples and 21 benign prostate hyperplasia samples were checked by using immunohistochemical staining. EphA1 mRNA was high expressed in LNCap, moderately expressed in 22RV1 and Du145, and lost in PC3. Loss of expression of EphA1 transcript was related to hypermethylation of CpG island around the translation start site. EphA1 protein was differentially expressed in prostate cancers and hyperplasia. Increased expression of EphA1 protein was more frequently detected in prostate cancers than in hyperplasia (P = 0.02), and more often detected in prostate cancer with high Gleason score (P < 0.001). Our data indicate that EphA1 receptor may have roles in carcinogenesis and progression of prostate cancer, and can be a potentially useful target for prognostic and therapeutic application. PMID:24040450

Peng, Libo; Wang, Haiyan; Dong, Yingchun; Ma, Jie; Wen, Juanjuan; Wu, Jinrong; Wang, Xueqing; Zhou, Xiaojun; Wang, Jiandong

2013-01-01

83

Ultrasound Doppler Score Correlates with OMERACT RAMRIS Bone Marrow Oedema and Synovitis Score in the Wrist Joint of Patients with Rheumatoid Arthritis  

DEFF Research Database (Denmark)

PURPOSE: MRI is considered the standard of reference for advanced imaging in rheumatoid arthritis (RA). However, in daily clinical practice ultrasound (US) imaging with Doppler information is more versatile and often used for fast and dynamic assessment of joint inflammation. The aim was to compare low-field MRI scores with the US Doppler measurements in the wrist joint of patients with RA. MATERIAL AND METHODS: Fifty consecutive patients with RA (46 women & 4 men) completed both low-field dedicated extremity MRI (E-scan®, Esaote) and a high-end US (Sequioa®, Siemens) imaging of the wrist before initiating either biological treatment (n = 26) or intraarticular injection of Depomedrole® (n = 24). Mean age was 56 years (range 21 - 83 years); mean disease duration 87.2 months (range 4 - 349 months), mean DAS 28 4,8 (range 2 - 7). MRI was scored according to the OMERACT RAMRIS recommendations and US Doppler colour-fractions were determined. RESULTS: Using Spearman's rho, we found a relatively good to moderate correlation between the US colour-fraction and the total OMERACT bone marrow oedema and synovitis scores on MRI (r = 0.6; p 

Boesen, M; Ellegaard, K

2012-01-01

84

Development of a new risk score for incident type 2 diabetes using updated diagnostic criteria in middle-aged and older chinese.  

Science.gov (United States)

Type 2 diabetes mellitus (T2DM) reaches an epidemic proportion among adults in China. However, no simple score has been created for the prediction of T2DM incidence diagnosed by updated criteria with hemoglobin A1c (HbA1c) ? 6.5% included in Chinese. In a 6-year follow-up cohort in Beijing and Shanghai, China, we recruited a total of 2529 adults aged 50-70 years in 2005 and followed them up in 2011. Fasting plasma glucose (FPG), HbA1c, and C-reactive protein (CRP) were measured and incident diabetes was identified by the recently updated criteria. Of the 1912 participants without T2DM at baseline, 924 were identified as having T2DM at follow-up, and most of them (72.4%) were diagnosed using the HbA1c criterion. Baseline body mass index, FPG, HbA1c, CRP, hypertension, and female gender were all significantly associated with incident T2DM. Based upon these risk factors, a simple score was developed with an estimated area under the receiver operating characteristic curve of 0.714 (95% confidence interval: 0.691, 0.737), which performed better than most of existing risk score models developed for eastern Asian populations. This simple, newly constructed score of six parameters may be useful in predicting T2DM in middle-aged and older Chinese. PMID:24819157

Ye, Xingwang; Zong, Geng; Liu, Xin; Liu, Gang; Gan, Wei; Zhu, Jingwen; Lu, Ling; Sun, Liang; Li, Huaixing; Hu, Frank B; Lin, Xu

2014-01-01

85

Development of a New Risk Score for Incident Type 2 Diabetes Using Updated Diagnostic Criteria in Middle-Aged and Older Chinese  

Science.gov (United States)

Type 2 diabetes mellitus (T2DM) reaches an epidemic proportion among adults in China. However, no simple score has been created for the prediction of T2DM incidence diagnosed by updated criteria with hemoglobin A1c (HbA1c) ?6.5% included in Chinese. In a 6-year follow-up cohort in Beijing and Shanghai, China, we recruited a total of 2529 adults aged 50–70 years in 2005 and followed them up in 2011. Fasting plasma glucose (FPG), HbA1c, and C-reactive protein (CRP) were measured and incident diabetes was identified by the recently updated criteria. Of the 1912 participants without T2DM at baseline, 924 were identified as having T2DM at follow-up, and most of them (72.4%) were diagnosed using the HbA1c criterion. Baseline body mass index, FPG, HbA1c, CRP, hypertension, and female gender were all significantly associated with incident T2DM. Based upon these risk factors, a simple score was developed with an estimated area under the receiver operating characteristic curve of 0.714 (95% confidence interval: 0.691, 0.737), which performed better than most of existing risk score models developed for eastern Asian populations. This simple, newly constructed score of six parameters may be useful in predicting T2DM in middle-aged and older Chinese. PMID:24819157

Ye, Xingwang; Zong, Geng; Liu, Xin; Liu, Gang; Gan, Wei; Zhu, Jingwen; Lu, Ling; Sun, Liang; Li, Huaixing; Hu, Frank B.; Lin, Xu

2014-01-01

86

Rheumatoid arthritis bone erosion volumes on CT and MRI: reliability and correlations with erosion scores on CT, MRI and radiography.  

DEFF Research Database (Denmark)

OBJECTIVES: To investigate intramodality and intermodality agreements of CT and MRI erosion volumes in metacarpophalangeal (MCP) joints in rheumatoid arthritis (RA), and to compare the volumes with erosion scores for CT, MRI and radiography. METHODS: In total, 17 patients with RA and four healthy controls underwent unilateral CT, MRI and radiography of second to fifth MCP joints in one hand. Erosion volumes (using OSIRIS software) and scores were determined from CT, MRI and radiography (scores only). RESULTS: CT, MRI and radiography detected 77, 62 and 12 erosions, respectively. On CT, the mean erosion volume was 26 mm(3) (median 10; range 0 to 248) and 30 mm(3) (18; 1 to 163) on MRI. Total erosion volumes (per patient/control) were 97 mm(3) (29; 0 to 485) on CT and 90 mm(3) (46; 0 to 389) on MRI. For volumes, Spearman correlation coefficients were 0.96 to 0.99 (CT vs CT), 0.95 to 0.98 (MRI vs MRI) and 0.64 to 0.89 (CT vs MRI), all p<0.01. MRI erosion volumes correlated with the Outcome Measures in Rheumatology Clinical Trials/Rheumatoid Arthritis Magnetic Resonance Imaging Score (OMERACT RAMRIS) erosion scores (0.91 to 0.99; p<0.01) and the Sharp/van der Heijde erosion score (0.49 to 0.63; p<0.01). CONCLUSION: Very high intramodality and high intermodality agreements of CT and MRI erosion volumes were found, encouraging further testing in longitudinal studies. A close correlation with CT and MRI erosion volumes supports the OMERACT RAMRIS erosion score as a valid measure of joint destruction in RA. Udgivelsesdato: 2007-Oct

MØller DØhn, Uffe; Ejbjerg, Bo J

2007-01-01

87

T2-weighted MRI in Parkinson's disease; Substantia nigra pars compacta hypointensity correlates with the clinical scores  

Directory of Open Access Journals (Sweden)

Full Text Available Background: Iron accumulation in substantia nigra pars compacta (SNpc and related intensity and volumetric changes in patients with idiopathic Parkinson's disease (PD has been reported previously. There are only a few studies evaluating the relation between neuroradiological findings and clinical scores, with contradictory results. Aims: In this study we aimed to measure the iron-rich brain areas of PD patients and healthy subjects with T2-weighted magnetic resonance imaging (MRI and to evaluate the relation between the clinical scores of PD patients and these imaging results. Methods and Materials: T2-weighted MRI findings were studied in 20 patients with PD and 16 healthy controls. The width of SNpc, putamen volume, and the intensity of the basal ganglia were measured. Unified Parkinson's Disease Rating Scale (UPDRS was used for evaluating the clinical status. Statistical Analyses: Mann Whitney U test for group comparisons, Wilcoxon sign rank test for comparisons within the patient group, and Spearman's rank correlation coefficient for analyses of correlations were used. Results: Mean SNpc and dentate nucleus intensities were lower in PD patients than healthy subjects. Mean SNpc width and putamen volumes were lower in patients. Decrease in the intensity of mean SNpc correlated with high UPDRS and rigidity scores. Conclusion: The results of our study reflect the increase in iron accumulation and oxidative stress in the SNpc in Parkinson's disease. The decrease in the intensity of SNpc correlates with poor clinical scores.

Atasoy Huseyin Tugrul

2004-07-01

88

Correlation of proton MR spectroscopic imaging with Galena's score based on step-section pathologic analysis after radical prostatectomy  

International Nuclear Information System (INIS)

Purpose: To determine whether hydrogen 1 magnetic resonance (MR) spectroscopic imaging can be used to predict aggressiveness of prostate cancer. Materials and Methods: All patients gave informed consent according to an institutionally approved research protocol. A total of 123 patients (median age, 58 years; age range, 40-74 years) who underwent endorectal MR imaging and MR spectroscopic imaging between January 2000 and December 2002 were included. MR imaging and spectroscopy were performed by using combined pelvic phased-array and endorectal probe. Water and lipids were suppressed, and phase-encoded data were acquired with 6.2-mm resolution. Voxels in the peripheral zone were considered suspicious for cancer if (Cho + Cr)/Cit was at least two standard deviations above the normal level, where Cho represents choline-containing compounds, Cr represents creatine and phosphocreatine, and Cit represents citrate. Correlation between metabolite ratio and four Gleason score groups identified at step-section pathologic evaluation (3 + 3, 3 + 4, 4 + 3, and > or =4 + 4) was assessed with generalized estimating equations. Results: Data from 94 patients were included. Pathologic evaluation was used to identify 239 lesions. Overall sensitivity of MR spectroscopic imaging was 56% for tumor detection, increasing from 44% in lesions with Gleason score of 3 + 3 to 89% in lesions with Gleason score greater than or equal to 4 + 4. There was a trend toward increasing (Cho + Cr)/Cit with ind toward increasing (Cho + Cr)/Cit with increasing Gleason score in lesions identified correctly with MR spectroscopic imaging. Tumor volume assessed with MR spectroscopic imaging increased with increasing Gleason score. Conclusion: MR spectroscopic imaging measurement of prostate tumor (Cho + Cr)/Cit and tumor volume correlate with pathologic Gleason score. There is overlap between MR spectroscopic imaging parameters at various Gleason score levels, which may reflect methodologic and physiologic variations. MR spectroscopic imaging has potential in noninvasive assessment of prostate cancer aggressiveness. (author)

89

Correlation between the elastic shear instability mechanism and empirical criteria for irradiation-induced amorphization  

International Nuclear Information System (INIS)

In an attempt to correlate the shear instability mechanism with empirical criteria for irradiation-induced amorphization, shear moduli of an A3B-type fcc crystal were calculated as a function of the chemical long range order parameter S using a Morse potential. The shear moduli were found to decrease with decreasing S. When the depth and the curvature of the A-B potential were changed while keeping the A-A and B-B potentials constant, the magnitude of the decrease in shear moduli is greater for deeper and narrower A-B potentials. The present results indicate that a shear instability should occur more readily in compounds with larger ordering energy and larger elastic moduli. These results agree with the reported empirical criteria for irradiation-induced amorphization, therefore providing further support for the shear instability mechanism for solid-state amorphization. (orig.)

90

Improvement of a new rotation function for molecular replacement by designing new scoring functions and dynamic correlation coefficient  

International Nuclear Information System (INIS)

A previously published new rotation function has been improved by using a dynamic correlation coefficient as well as two new scoring functions of relative entropy and mean-square-residues to make the rotation function more robust and independent of a specific set of weights for scoring and ranking. The previously described new rotation function calculates the rotation function of molecular replacement by matching the search model directly with the Patterson vector map. The signal-to-noise ratio for the correct match was increased by averaging all the matching peaks. Several matching scores were employed to evaluate the goodness of matching. These matching scores were then combined into a single total score by optimizing a set of weights using the linear regression method. It was found that there exists an optimal set of weights that can be applied to the global rotation search and the correct solution can be ranked in the top 100 or less. However, this set of optimal weights in general is dependent on the search models and the crystal structures with different space groups and cell parameters. In this work, we try to solve this problem by designing a dynamic correlation coefficient. It is shown that the dynamic correlation coefficient works for a variety of space groups and cell parameters in the global search of rotation function. We also introduce two new matching scores: relative entropy and mean-square-residues. Last but not least, we discussed a valid method for the optimization of the adjustable parameters for matching vectors. (condensed matter: structure, thermal and mechanical properties)

91

Cognitive Entry Characteristics and Semester Examination Scores as Correlates of College Students’ Achievement in Mathematics  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Aims: This study was designed (i) to investigate the relationship between cognitive entry characteristics (CEC), semester examination scores and student’s achievement in mathematics and (ii) to find out the predictive strength of CEC and semester examination scores on college students’ achievement in mathematics. Study Design: The study employed ex-post facto design. Place and Duration of Study: College of Education, Ikere-Ekiti, Eki...

James Ajogbeje Oke; Tunde Borisade Fidelis

2013-01-01

92

PERFORMANCE RANKING OF DIPLOMA INSTITUTIONS BASED ON SOME SELECTED CRITERIA BY APPLYING SCORING MODEL- A SAMPLE STUDY  

Directory of Open Access Journals (Sweden)

Full Text Available The assessment of institutional performance based on various contributing parameters is of paramount importance for an institute and is not an easy task. Present studies aim at assessing the institutional level performance of some selected diploma level institutions of West Bengal by using Scoring Model (SM - as a multiple criterion decision making technique. Application of this model also shows a comparison of institutions based on their performance with respect to specific contributing parameters.

Dipankar Bose

2011-10-01

93

Advanced Taste Sensors Based on Artificial Lipids with Global Selectivity to Basic Taste Qualities and High Correlation to Sensory Scores  

Directory of Open Access Journals (Sweden)

Full Text Available Effective R&D and strict quality control of a broad range of foods, beverages, and pharmaceutical products require objective taste evaluation. Advanced taste sensors using artificial-lipid membranes have been developed based on concepts of global selectivity and high correlation with human sensory score. These sensors respond similarly to similar basic tastes, which they quantify with high correlations to sensory score. Using these unique properties, these sensors can quantify the basic tastes of saltiness, sourness, bitterness, umami, astringency and richness without multivariate analysis or artificial neural networks. This review describes all aspects of these taste sensors based on artificial lipid, ranging from the response principle and optimal design methods to applications in the food, beverage, and pharmaceutical markets.

Yoshikazu Kobayashi

2010-04-01

94

Color/power Doppler transrectal US in prostate cancer: Correlation with Gleason score  

International Nuclear Information System (INIS)

To evaluate the relationship between hypervascularity on color/power Doppler transrectal ultrasonography and the Gleason score of corresponding biopsied specimen in patients with prostatic cancer. From July 1998 to March 2002, one hundred fifty seven patients with pathologically proven prostate cancer at this institution were included, and all of them underwent transrectal ultrasonographic examination. Initially, ultrasonographic findings and pathologic data of 129 patients were retrospectively reviewed and excluded 28 patients whose sonographic images were either unavailable or inconclusive. The presence of hypoechoic lesion on transrectal sonography and hypervascularity on color/power Doppler sonography in the peripheral zone of the prostate was first evaluated, and these sonographic findings and Gleason score of the corresponding biopsied specimen were then compared. Statistical analysis was done by Student t-test using SPSS package. Among one hundred twenty nine patients, ninety four patients had a hypoechoic lesion on gray scale sonography while sixty one showed a hypervascular lesion on color/power Doppler sonography. Fifty seven of 61 patients (93.4%) had hypoechoic lesion on gray scale sonography. The mean Gleason score of patients with hypervascular lesion was 7.9 ± 0.98 whereas that of the patients without hypervascular lesion, 6.9 ± 1.22, showing a statistically significant difference (p<0.01). Prostate cancer with hypervascularity on transrectal sonography appears to have a higher Gleason score on pathologic examination than that without hypervascularity.

95

Quantification of Emphysema with a Three-Dimensional Chest CT Scan: Correlation with the Visual Emphysema Scoring on Chest CT, Pulmonary Function Tests and Dyspnea Severity  

International Nuclear Information System (INIS)

We wanted to prospectively evaluate the correlation between the quantification of emphysema using 3D CT densitometry with the visual emphysema score, pulmonary function tests (PFT) and the dyspnea score in patients with chronic obstructive pulmonary disease (COPD). Non-enhanced chest CT with 3D reconstruction was performed in 28 men with COPD (age 54-88 years). With histogram analysis, the total lung volume, mean lung density and proportion of low attenuation lung volume below predetermined thresholds were measured. The CT parameters were compared with the visual emphysema score, the PFT and the dyspnea score. A low attenuation lung volume below -950 HU was well correlated with the DLco and FEV1/FVC. A Low attenuation lung volume below -950 HU and -930 HU was correlated with visual the emphysema score. A low attenuation lung volume below -950 HU was correlated with the dyspnea score, although the correlations between the other CT parameters and the dyspnea score were not significant. Objective quantification of emphysema using 3D CT densitometry was correlated with the visual emphysema score. A low attenuation lung volume below -950 HU was correlated with the DLco, the FEV1/FVC and the dyspnea score.

96

Quantification of Emphysema with a Three-Dimensional Chest CT Scan: Correlation with the Visual Emphysema Scoring on Chest CT, Pulmonary Function Tests and Dyspnea Severity  

Energy Technology Data Exchange (ETDEWEB)

We wanted to prospectively evaluate the correlation between the quantification of emphysema using 3D CT densitometry with the visual emphysema score, pulmonary function tests (PFT) and the dyspnea score in patients with chronic obstructive pulmonary disease (COPD). Non-enhanced chest CT with 3D reconstruction was performed in 28 men with COPD (age 54-88 years). With histogram analysis, the total lung volume, mean lung density and proportion of low attenuation lung volume below predetermined thresholds were measured. The CT parameters were compared with the visual emphysema score, the PFT and the dyspnea score. A low attenuation lung volume below -950 HU was well correlated with the DLco and FEV{sub 1}/FVC. A Low attenuation lung volume below -950 HU and -930 HU was correlated with visual the emphysema score. A low attenuation lung volume below -950 HU was correlated with the dyspnea score, although the correlations between the other CT parameters and the dyspnea score were not significant. Objective quantification of emphysema using 3D CT densitometry was correlated with the visual emphysema score. A low attenuation lung volume below -950 HU was correlated with the DLco, the FEV{sub 1}/FVC and the dyspnea score.

Park, Hyun Jeong; Hwang, Jung Hwa [Dept. of Radiology, Soonchunhyang University Seoul Hospital, Seoul (Korea, Republic of)

2011-09-15

97

Correlates of Children's Eating Attitude Test scores among primary school children.  

Science.gov (United States)

A total of 107 Malay primary school girls (8-9 yr. old) completed a set of measurements on eating behavior (ChEAT, food neophobia scales, and dieting experience), the Rosenberg Self-Esteem Scale, body shape satisfaction, dietary intake, weight, and height. About 38% of the girls scored 20 and more on the ChEAT, and 46% of them reported dieting by reducing sugar and sweets (73%), skipping meals (67%), reducing fat foods (60%) and snacks (53%) as the most frequent methods practiced. In general, those girls with higher ChEAT scores tended to have lower self-esteem (r=.39), indicating they were more unwilling to try new foods (food neophobic) (r=.29), chose a smaller figure for desired body size (r=-.25), and were more dissatisfied with their body size (r=.31). PMID:15974357

Shariff, Zalilah Mohd; Yasin, Zaidah Mohamed

2005-04-01

98

Correlating PSA, bone scan and Gleason score in prostate cancer patients  

International Nuclear Information System (INIS)

The hypothesis was that Gleason Score was more important than PSA in predicting bone metastases in prostate cancer patients. The objective of the work was to identify a group of low risk in which bone scan could be omitted. Clinical records of 165 patients with recently diagnosed prostate cancer, who had had, between January of 1993 and December of 1995, bone scans, PSA and Gleason determinations, were reviewed. 5,5% had well differentiated cancer. 49,7% had a negative bone scan. The risk of bone metastases in spite of levels of PSA < 10-20 ng / mL is not worthless in patients with prostate cancer Gleason Score 7-9. (author)

99

Brochopulmonary dysplasia: New high resolution computed tomography scorting system and correlation between the high resolution computed tomography score and clinical severity  

Energy Technology Data Exchange (ETDEWEB)

To develop an high resolution computed tomography (HRCT) scoring system for the assessment of bronchopulmonary dysplasia (BPD) and determine its usefulness as compared with the chest radiographic score. Forty-two very low-birth-weight preterm infants with BPD (25 male, 17 female) were prospectively evaluated with HRCT performed at the mean age of 39.1-week postmenstrual age. Clinical severity of BPD was categorized as mild, moderate or severe. The HRCT score (0-36) of each patient was the sum of the number of bronchopulmonary segments with 1) hyperaeration and 2) parenchymal lesions (linear lesions, segmental atelectasis, consolidation and architectural distortion), respectively. We compared the HRCT scores with the chest radiographic scores (the Toce system) in terms of correlation with clinical severity. The HRCT score had good interobserver (r = 0.969, p < 0.001) and intraobserver (r = 0.986, p < 0.001) reproducibility. The HRCT score showed better correlation (r = 0.646, p < 0.001) with the clinical severity of BPD than the chest radiographic score (r = 0.410, p = 0.007). The hyperaeration score showed better correlation (r = 0.738, p < 0.001) with the clinical severity of BPD than the parenchymal score (r = 0.523, p < 0.001). We have developed a new HRCT scoring system for BPD based on the quantitative evaluation of pulmonary abnormalities of BPD consisting of the hyperaeration score and the parenchymal score. The HRCT score shows better correlation with the clinical severity of BPD than the radiographic score.

Shin, Sumi; Kim, Woo Sun; Cheon, Jung Eun; Kim, Han Suk; Lee, Whal; Jung, Ah Young; Kim, In One; Choi, Jung Hwan [Seoul National University College of Medicine, Seoul (KR)

2013-04-15

100

Brochopulmonary dysplasia: New high resolution computed tomography scorting system and correlation between the high resolution computed tomography score and clinical severity  

International Nuclear Information System (INIS)

To develop an high resolution computed tomography (HRCT) scoring system for the assessment of bronchopulmonary dysplasia (BPD) and determine its usefulness as compared with the chest radiographic score. Forty-two very low-birth-weight preterm infants with BPD (25 male, 17 female) were prospectively evaluated with HRCT performed at the mean age of 39.1-week postmenstrual age. Clinical severity of BPD was categorized as mild, moderate or severe. The HRCT score (0-36) of each patient was the sum of the number of bronchopulmonary segments with 1) hyperaeration and 2) parenchymal lesions (linear lesions, segmental atelectasis, consolidation and architectural distortion), respectively. We compared the HRCT scores with the chest radiographic scores (the Toce system) in terms of correlation with clinical severity. The HRCT score had good interobserver (r = 0.969, p < 0.001) and intraobserver (r = 0.986, p < 0.001) reproducibility. The HRCT score showed better correlation (r = 0.646, p < 0.001) with the clinical severity of BPD than the chest radiographic score (r = 0.410, p = 0.007). The hyperaeration score showed better correlation (r = 0.738, p < 0.001) with the clinical severity of BPD than the parenchymal score (r = 0.523, p < 0.001). We have developed a new HRCT scoring system for BPD based on the quantitative evaluation of pulmonary abnormalities of BPD consisting of the hyperaeration score and the parenchymal score. The HRCT score shows better correlation with the clinical severity of BPD than the radiographic score.

 
 
 
 
101

Severity assessment of pulmonary embolism using dual energy CT - correlation of a pulmonary perfusion defect score with clinical and morphological parameters of blood oxygenation and right ventricular failure  

Energy Technology Data Exchange (ETDEWEB)

To correlate a Dual Energy (DE)-based visual perfusion defect scoring system with established CT-based and clinical parameters of pulmonary embolism (PE) severity. In 63 PE patients, DE perfusion maps were visually scored for perfusion defects (P-score). Vascular obstruction was quantified using the Mastora score. Both scores were correlated with short-axis diameters of the right and left ventricle, their ratio (RV/LV ratio), width of the pulmonary trunk, a number of clinical parameters and each other. Univariate and multivariate analyses were performed. Times to generate both scores were recorded. After univariate and multivariate analysis, a significant (p < 0.05) correlation with the P-score was shown for the Mastora score (r = 0.65), RV/LV ratio (r = 0.47), width of the pulmonary trunk (r = 0.26), troponin I (r = 0.43) and PaO{sub 2} (r = -0.50). For the left ventricular diameter, only univariate analysis showed a significant correlation. Mastora score correlated significantly with RV/LV ratio (r = 0.36), width of the pulmonary trunk (r = 0.27), PaO{sub 2} (r = -0.41) and troponin I (r = 0.37). Mean time for generating the P-score was significantly shorter than for the Mastora score. A DE-based P-score correlates with a number of parameters of PE severity. It might be easier and faster to perform than some traditional CT scoring methods for vascular obstruction. (orig.)

Thieme, Sven F. [Ludwig-Maximilians-Universitaet, Department of Clinical Radiology, Muenchen (Germany); Institut fuer Klinische Radiologie der LMU Muenchen, Muenchen (Germany); Ashoori, Nima; Bamberg, Fabian; Sommer, Wieland H.; Johnson, Thorsten R.C.; Maxien, Daniel; Helck, Andreas D.; Reiser, Maximilian F.; Nikolaou, Konstantin [Ludwig-Maximilians-Universitaet, Department of Clinical Radiology, Muenchen (Germany); Leuchte, Hanno; Becker, Alexander [Ludwig-Maximilians-Universitaet, Department of Medicine I, Muenchen (Germany); Behr, Juergen [Ludwig-Maximilians-Universitaet, Department of Medicine I, Muenchen (Germany); Berufsgenossenschaftliches Universitaetsklinikum Bergmannsheil GmbH Ruhr-Universitaet Bochum, Department of Medicine III, Bochum (Germany)

2012-02-15

102

Correlation between Grades in the Medical Basic Science Course and Scores on the Comprehensive Basic Sciences Exam in Iran  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction: Medical students in Iran are required to undertake a Basic Sciences Comprehensive Exam (BSCE at the end of their BS course in order to progress to the next stage of medical education. BSCE results are widely used to evaluate medical education programs among different medical universities. The aim of this study is to explore the correlation between BSCE results and students’ mean BS course scores.Methods: A cross-sectional study, using secondary data analysis, was carried out in 2007 in Hormozgan University of Medical Sciences (HUMS in Iran. Data from the 20th BSCE (held in 1998 to the 36th BSCE (held in 2006 was collected. All medical students who took these exams and for whom the mean results of the BS course and the BSCE were available were eligible for inclusion in the study. For each medical student, data were obtained regarding age at the time of participation in BSCE, together with sex, entrance year, zone as categorised by the national quota system, mean BS course scores, BSCE result, duration of BS course (number of semesters and number of failed semesters. Students whose data was not complete were excluded from the study. Data was analysed by using SPSS 15 (SPSS Inc., Chicago, Illinois, USA software.Results: 372 students undertook the BSCE during the research study period. Complete data was available for 365 medical students (98.1%. Among the participants, 224 (61.4% were female and 141 (38.6% were male. The mean age at the time of sitting the BSCE was 22.01±1.22. Mean BSCE scores were higher among students who had not previously failed a semester and who also finished the BS course within five semesters. Students with higher BS course scores had higher BSCE scores (P=0.000.Conclusions: Students’ BS course scores were found to correlate to BSCE results. Hence it may be prudent to identify medical students with low BS course scores, in order to provide additional educational support to improve their medical knowledge and thereby enhance their performance on the BSCE.

Hamidreza Mahboobi

2010-07-01

103

Scoring of senescence signalling in multiple human tumour gene expression datasets, identification of a correlation between senescence score and drug toxicity in the NCI60 panel and a pro-inflammatory signature correlating with survival advantage in peritoneal mesothelioma  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Cellular senescence is a major barrier to tumour progression, though its role in pathogenesis of cancer and other diseases is poorly understood in vivo. Improved understanding of the degree to which latent senescence signalling persists in tumours might identify intervention strategies to provoke "accelerated senescence" responses as a therapeutic outcome. Senescence involves convergence of multiple pathways and requires ongoing dynamic signalling throughout its establishment and maintenance. Recent discovery of several new markers allows for an expression profiling approach to study specific senescence phenotypes in relevant tissue samples. We adopted a "senescence scoring" methodology based on expression profiles of multiple senescence markers to examine the degree to which signals of damage-associated or secretory senescence persist in various human tumours. Results We first show that scoring captures differential induction of damage or inflammatory pathways in a series of public datasets involving radiotherapy of colon adenocarcinoma, chemotherapy of breast cancer cells, replicative senescence of mesenchymal stem cells, and progression of melanoma. We extended these results to investigate correlations between senescence score and growth inhibition in response to ~1500 compounds in the NCI60 panel. Scoring of our own mesenchymal tumour dataset highlighted differential expression of secretory signalling pathways between distinct subgroups of MPNST, liposarcomas and peritoneal mesothelioma. Furthermore, a pro-inflammatory signature yielded by hierarchical clustering of secretory markers showed prognostic significance in mesothelioma. Conclusions We find that "senescence scoring" accurately reports senescence signalling in a variety of situations where senescence would be expected to occur and highlights differential expression of damage associated and secretory senescence pathways in a context-dependent manner.

Burns Sharon

2010-10-01

104

Efficacy of HUMN criteria for scoring the micronucleus assay in human lymphocytes exposed to a low concentration of p,p'-DDT  

Directory of Open Access Journals (Sweden)

Full Text Available The cytokinesis-block micronucleus (CBMN assay is one of the standard cytogenetic tools employed to assess chromosomal damage subsequent to exposure to genotoxic/cytotoxic agents, and is widely applicable to plant, animal and human cells. In the present study, the CBMN assay was used to assess the baseline damage in binuclear human peripheral blood lymphocytes exposed to 25 µg/L p,p'-DDT for 1, 2, 24, and 48 h by measuring the frequency of micronuclei, nucleoplasmic bridges and nuclear buds. These new scoring criteria facilitated the detection of different types of clastogenic and aneugenic effects induced by this type of pollutant. With these criteria, CBMN can also be used to measure nucleoplasmic bridges which are considered to be consequences of chromosome rearrangements and nuclear buds which are biomarkers of altered gene amplification and gene dosage. The total number of micronuclei observed in binuclear human peripheral blood lymphocytes of the exposed samples (ranging from 32 to 47 was significantly greater (P < 0.05 than that detected in the unexposed (0 time control sample, where the total number of micronuclei was 7. The number of nucleoplasmic bridges and nuclear buds obtained after 24 and 48 h was also significantly (P < 0.05 greater in the samples treated with p,p'-DDT than in the unexposed control samples. Thus, our results confirmed the usefulness of the new criteria applicable for the CBMN assay employed in measuring the DNA damage and its role of a sensitive cytogenetic biomarker.

V. Garaj-Vrhovac

2008-06-01

105

Urinary homocysteic acid levels correlate with mini-mental state examination scores in Alzheimer's disease patients.  

Science.gov (United States)

Homocysteic acid (HA) has been suggested as a pathogen in a mouse model of Alzheimer's disease (AD), 3xTg-AD. However, it is not established whether HA is involved in humans. We investigated the relationship between urinary HA levels and Mini-Mental State Examination (MMSE) scores in AD patients (n = 70) and non-AD controls (n = 34). We found a positive, statistically significant relationship between the two variables (the urinary HA level and MMSE score) (r = 0.31, p = 0.0008, n = 70). This relationship was stronger in females than males (r = 0.43, p = 0.005, n = 44 in females; r = 0.48, p = 0.02, n = 22 in males). The urinary HA levels were significantly different in AD patients than controls (AD: 8.7 ± 7.5, n = 70; non-dementia control: 13.3 ± 9.4, n = 34, p < 0.01). In addition, aging and smoking were found as lowering factors for urinary HA levels. Our preliminary study showed a negative, statistically significant relationship between blood HA (micromole) and urine HA levels (r = -0.6, p = 0.007, n = 19), and between blood HA levels and MMSE scores (r = -0.79, p = 0.0000518, n = 19). On the basis of these results, we speculate that reduced urinary excretion induces elevated HA levels in blood, resulting in cognitive dysfunctions. This study also suggests that HA may be a candidate of neurotoxins for uremic encephalopathy. Since amyloid-? increases HA toxicity and HA is an agonist of N-methyl-D-aspartic acid (NMDA) receptor, we speculate that elevated blood HA affects the brain cognitive function through NMDA receptor-mediated toxicity in AD. PMID:22531414

Hasegawa, Tohru; Ichiba, Masayoshi; Matsumoto, Shin-Ei; Kasanuki, Koji; Hatano, Taku; Fujishiro, Hiroshige; Iseki, Eizo; Hattori, Nobutaka; Yamada, Tatsuo; Tabira, Takeshi

2012-01-01

106

Correlation between PSA, bone scan and Gleason score in patients with prostate cancer  

International Nuclear Information System (INIS)

Full text: Prostate cancer is the third most common cancer among Peruvian males. Although radionuclide bone scans (BS) are frequently recommended as part of the staging evaluation for newly diagnosed prostate cancer, most scans are negative for metastases. It has been suggested that a routine bone scan is unnecessary in recently diagnosed prostate cancer if serum PSA is under 10 ng/mL. We hypothesized that Gleason score plus prostate-specific antigen (PSA), could predict for a positive bone scan (better that PSA alone), and that a low - risk group of patients could be identified in whom BS might be omitted. All patients who had both pathologic review of their prostate cancer biopsies and radionuclide BS at our institution from 1/93 to 12/95 were studied. Gleason score, PSA, and bone scan (Soloway Index) were determined in 165 patients. Bivariate analysis using chi (x2) was performed. The mean age of the 165 patients was 71.3 years, 109/165 (66.1%) had a 7-9 Gleason score and only 9/165 (5.5%) were well differentiated prostrate cancer. 82/165 (49.7%) had negative BS. When classifying patients according to their histological grade, the PSA median values were 11.8 ng/mL, 74.8 ng/mL and 116.4 ng/mL in well, median and poorly differentiated prostate cancer respectively. Using a cut off point of 10 ng/mL of PSA, the probability of having a positive BS in Gleason 7, 8 and 9 tumors were 0.109, 0.121 and 0.133 respectively. By using a cut off point of 20 ng/mL of PSA the possibility to have a positive BS in Gleason 7, 8 and 9 tumours were 0.182, 0.206 and 0.224 respectively. Gleason score plus PSA were independent predictors for a positive radionuclide BS in newly diagnosed prostate cancer patients. Considering that most of our patients have Gleason 7-9, the risk of bone metastases despite PSA levels between 10 - 20 ng/mL is not negligible. In our opinion, it is important to continue including bone scan in the staging assessment of prostate cancer. (author)

107

Severity of acute pulmonary embolism: evaluation of a new spiral CT angiographic score in correlation with echocardiographic data  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this study was to investigate whether the severity of acute pulmonary embolism (PE) could be quantitatively assessed with spiral CT angiography (SCTA). Thirty-six consecutive patients without underlying cardiopulmonary disease and high clinical suspicion of PE underwent prospectively thin-collimation SCTA and echocardiography at the time of the initial diagnosis (T0) and after initial therapy (T1; mean interval of time T1-T2: 32 days). The CT severity score was based on the percentage of obstructed surface of each central and peripheral pulmonary arterial section using a 5-point scale (1: <25%; 2: 25-49%; 3: 50-74%; 4: 75-99%; 5: 100%). The sum of the detailed scores attributed to 5 mediastinal, 6 lobar and 20 segmental arteries per patient led to the determination of central, peripheral and global CT severity scores and subsequent determination of percentages of obstruction of the pulmonary circulation. Echocardiographic severity criteria included the presence of signs of acute cor pulmonale and/or systolic pulmonary hypertension (>40 mm Hg). The SCTA depicted acute PE in all patients at T0 with complete resolution of endovascular clots in 10 patients at T1. At T0, the mean percentage of obstruction of the pulmonary arterial bed was significantly higher in the 22 patients with echocardiographic signs of severity (56{+-}13 vs 28{+-}32%; p<0.001). A significant reduction in the mean percentage of pulmonary artery obstruction was observed in the 19 patients with resolution of echocardiographic criteria of severity between T0 and T1 T0: 57{+-}14%; T1: 7{+-}11%; p<0.001. The threshold value for severe PE on CT angiograms was 49% (sensitivity: 0.773; specificity: 0.214). The mean ({+-}SD) pulmonary artery pressure was significantly higher in the 26 patients with more than 50% obstruction of the pulmonary artery bed (45{+-}15 mm Hg) than in the 10 patients with less than 50% obstruction of pulmonary artery bed at T0 (31{+-}11 mm Hg; p<0.01). The CT severity score evaluated in the present study enables quantitative assessment of acute PE severity on spiral CT angiograms, readily applicable in routine clinical practice. (orig.)

Mastora, Ioana; Remy-Jardin, Martine; Masson, Pascal; Remy, Jacques [Department of Radiology, University Center Hospital Calmette, Boulevard Jules Leclerc, 59037 Lille Cedex (France); Medical Research Group ' ' Equipe d' Accueil no. 2682' ' , Boulevard Jules Leclerc, 59037 Lille Cedex (France); Galland, Eric; Bauchart, Jean-Jacques [Department of Cardiology, University Center Cardiology Hospital; Boulevard Jules Leclerc, 59037 Lille Cedex (France); Delannoy, Valerie [Department of Medical Statistics, University of Lille, Place de Verdun, 59037 Lille Cedex (France)

2003-01-01

108

Correlation of foot bimalleolar angle with Pirani score to assess the severity of congenital talipes equinovarus deformity.  

Science.gov (United States)

Various reported scores for congenital talipes equinovarus are presented with observer variations and lack in objective evidence of severity of deformity. Anteromedial foot bimalleolar angle (FBM), an objective assessment of deformity and correction, was correlated and compared with Pirani scores 0.5-2, 2.5-4, 4.5-6 as grouped I to III for mean and SD in 244 club feet in 137 children. The mean FBM angles of groups I to III were 79.72°, 68.4°, and 53.27°, respectively. The FBM angle gives an objective assessment of the severity of deformity and can be used as objective evidence of improvement/deterioration of deformity. PMID:21912337

Jain, Pragya; Mehtani, Anil; Goel, Meenakshi; Jain, Saurabh; Sood, Alok; Kumar Jain, Anil

2012-01-01

109

Correlation between Grade Point Averages and Student Evaluation of Teaching Scores: Taking a Closer Look  

Science.gov (United States)

One of the most contentious potential sources of bias is whether instructors who give higher grades receive higher ratings from students. We examined the grade point averages (GPAs) and student ratings across 2073 general education religion courses at a large private university. A moderate correlation was found between GPAs and student evaluations…

Griffin, Tyler J.; Hilton, John, III.; Plummer, Kenneth; Barret, Devynne

2014-01-01

110

DNA repair pathway gene expression score correlates with repair proficiency and tumor sensitivity to chemotherapy.  

Science.gov (United States)

Mutagenesis is a hallmark of malignancy, and many oncologic treatments function by generating additional DNA damage. Therefore, DNA damage repair is centrally important in both carcinogenesis and cancer treatment. Homologous recombination (HR) and nonhomologous end joining are alternative pathways of double-strand DNA break repair. We developed a method to quantify the efficiency of DNA repair pathways in the context of cancer therapy. The recombination proficiency score (RPS) is based on the expression levels for four genes involved in DNA repair pathway preference (Rif1, PARI, RAD51, and Ku80), such that high expression of these genes yields a low RPS. Carcinoma cells with low RPS exhibit HR suppression and frequent DNA copy number alterations, which are characteristic of error-prone repair processes that arise in HR-deficient backgrounds. The RPS system was clinically validated in patients with breast or non-small cell lung carcinomas (NSCLCs). Tumors with low RPS were associated with greater mutagenesis, adverse clinical features, and inferior patient survival rates, suggesting that HR suppression contributes to the genomic instability that fuels malignant progression. This adverse prognosis associated with low RPS was diminished if NSCLC patients received adjuvant chemotherapy, suggesting that HR suppression and associated sensitivity to platinum-based drugs counteract the adverse prognosis associated with low RPS. Therefore, RPS may help oncologists select which therapies will be effective for individual patients, thereby enabling more personalized care. PMID:24670686

Pitroda, Sean P; Pashtan, Itai M; Logan, Hillary L; Budke, Brian; Darga, Thomas E; Weichselbaum, Ralph R; Connell, Philip P

2014-03-26

111

Efficacy of HUMN criteria for scoring the micronucleus assay in human lymphocytes exposed to a low concentration of p,p'-DDT  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in english The cytokinesis-block micronucleus (CBMN) assay is one of the standard cytogenetic tools employed to assess chromosomal damage subsequent to exposure to genotoxic/cytotoxic agents, and is widely applicable to plant, animal and human cells. In the present study, the CBMN assay was used to assess the [...] baseline damage in binuclear human peripheral blood lymphocytes exposed to 25 µg/L p,p'-DDT for 1, 2, 24, and 48 h by measuring the frequency of micronuclei, nucleoplasmic bridges and nuclear buds. These new scoring criteria facilitated the detection of different types of clastogenic and aneugenic effects induced by this type of pollutant. With these criteria, CBMN can also be used to measure nucleoplasmic bridges which are considered to be consequences of chromosome rearrangements and nuclear buds which are biomarkers of altered gene amplification and gene dosage. The total number of micronuclei observed in binuclear human peripheral blood lymphocytes of the exposed samples (ranging from 32 to 47) was significantly greater (P

V., Garaj-Vrhovac; G., Gajski; S., Ravli& #263; .

2008-06-01

112

Efficacy of HUMN criteria for scoring the micronucleus assay in human lymphocytes exposed to a low concentration of p,p'-DDT  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in english The cytokinesis-block micronucleus (CBMN) assay is one of the standard cytogenetic tools employed to assess chromosomal damage subsequent to exposure to genotoxic/cytotoxic agents, and is widely applicable to plant, animal and human cells. In the present study, the CBMN assay was used to assess the [...] baseline damage in binuclear human peripheral blood lymphocytes exposed to 25 µg/L p,p'-DDT for 1, 2, 24, and 48 h by measuring the frequency of micronuclei, nucleoplasmic bridges and nuclear buds. These new scoring criteria facilitated the detection of different types of clastogenic and aneugenic effects induced by this type of pollutant. With these criteria, CBMN can also be used to measure nucleoplasmic bridges which are considered to be consequences of chromosome rearrangements and nuclear buds which are biomarkers of altered gene amplification and gene dosage. The total number of micronuclei observed in binuclear human peripheral blood lymphocytes of the exposed samples (ranging from 32 to 47) was significantly greater (P

V., Garaj-Vrhovac; G., Gajski; S., Ravli& #263; .

113

Correlation between a new visual prostate symptom score (VPSS) and uroflowmetry parameters in men with lower urinary tract symptoms  

Scientific Electronic Library Online (English)

Full Text Available SciELO South Africa | Language: English Abstract in english OBJECTIVE: A visual prostate symptom score (VPSS) compared with the international prostate symptom score (IPSS) for evaluation of lower urinary tract symptoms (LUTS) can be completed without physician assistance by a significantly larger proportion of men with limited education. We aimed to evaluate [...] the correlation of the VPSS and IPSS with uroflowmetry parameters. METHODS: Men with LUTS were requested to complete the IPSS and VPSS, consisting of pictograms to evaluate urinary frequency, nocturia, force of the stream and quality of life. The maximum (Qmax) and average urinary flow rate (Qave), voided volume (VV) and post-void residual (PVR) urine volumes were measured. Statistical analysis was performed using the Mann-Whitney and Spearman's tests. RESULTS: The study included 93 men (mean age 64 years, range 33 -85), with VV >150 ml in 66 (71%) and 150 ml there were significant negative correlations between the IPSS and Qmax (r=-0.30, p=0.016), the IPSS and Qave (r=-0.29, p=0.018), the VPSS and Qmax (r=-0.38, p

C F, Heyns; C L E, van der Walt; A E, Groeneveld.

2012-04-01

114

Distribution of brain infarction in children with tuberculous meningitis and correlation with outcome score at 6 months  

Energy Technology Data Exchange (ETDEWEB)

Prognostic indicators for tuberculous meningitis (TBM) offer realistic expectations for parents of affected children. Infarctions affecting the basal ganglia are associated with a poor outcome. To correlate the distribution of infarction in children with TBM on CT with an outcome score (OS). CT brain scans in children with TBM were retrospectively reviewed and the distribution of infarctions recorded. The degree of correlation with OS at 6 months was determined. There was a statistically significant association between all sites of infarction (P = 0.0001-0.001), other than hemispheric (P = 0.35), and outcome score. There was also a statistically significant association between all types of infarction (P = 0.0001-0.02), other than hemispheric (P = 0.05), and overall poor outcome. The odds ratio for poor outcome with bilateral basal ganglia and internal capsule infarction was 12. The odds ratio for poor outcome with 'any infarction' was 4.91 (CI 2.24-10.74), with 'bilateral infarctions' 8.50 (CI 2.49-28.59), with basal ganglia infarction 5.73 (CI 2.60-12.64), and for hemispheric infarction 2.30 (CI 1.00-5.28). Infarction is associated with a poor outcome unless purely hemispheric. MRI diffusion-weighted imaging was not part of this study, but is likely to play a central role in detecting infarctions not demonstrated by CT. (orig.)

Andronikou, Savvas [University of Stellenbosch, Department of Radiology, Tygerberg Hospital, P.O. Box 19063, Tygerberg (South Africa); Wilmshurst, Jo; Hatherill, Mark [University of Cape Town, Pediatric Neurology, Red Cross Children' s Hospital, School of Child and Adolescent Health, Cape Town (South Africa); VanToorn, Ronald [University of Stellenbosch, Department of Pediatric Neurology, Tygerberg Hospital, Cape Town (South Africa)

2006-12-15

115

Distribution of brain infarction in children with tuberculous meningitis and correlation with outcome score at 6 months  

International Nuclear Information System (INIS)

Prognostic indicators for tuberculous meningitis (TBM) offer realistic expectations for parents of affected children. Infarctions affecting the basal ganglia are associated with a poor outcome. To correlate the distribution of infarction in children with TBM on CT with an outcome score (OS). CT brain scans in children with TBM were retrospectively reviewed and the distribution of infarctions recorded. The degree of correlation with OS at 6 months was determined. There was a statistically significant association between all sites of infarction (P = 0.0001-0.001), other than hemispheric (P = 0.35), and outcome score. There was also a statistically significant association between all types of infarction (P = 0.0001-0.02), other than hemispheric (P = 0.05), and overall poor outcome. The odds ratio for poor outcome with bilateral basal ganglia and internal capsule infarction was 12. The odds ratio for poor outcome with 'any infarction' was 4.91 (CI 2.24-10.74), with 'bilateral infarctions' 8.50 (CI 2.49-28.59), with basal ganglia infarction 5.73 (CI 2.60-12.64), and for hemispheric infarction 2.30 (CI 1.00-5.28). Infarction is associated with a poor outcome unless purely hemispheric. MRI diffusion-weighted imaging was not part of this study, but is likely to play a central role in detecting infarctions not demonstrated by CT. (orig.)

116

Genetic Risk Score of NOS Gene Variants Associated with Myocardial Infarction Correlates with Coronary Incidence across Europe  

Science.gov (United States)

Coronary artery disease (CAD) mortality and morbidity is present in the European continent in a four-fold gradient across populations, from the South (Spain and France) with the lowest CAD mortality, towards the North (Finland and UK). This observed gradient has not been fully explained by classical or single genetic risk factors, resulting in some cases in the so called Southern European or Mediterranean paradox. Here we approached population genetic risk estimates using genetic risk scores (GRS) constructed with single nucleotide polymorphisms (SNP) from nitric oxide synthases (NOS) genes. These SNPs appeared to be associated with myocardial infarction (MI) in 2165 cases and 2153 controls. The GRSs were computed in 34 general European populations. Although the contribution of these GRS was lower than 1% between cases and controls, the mean GRS per population was positively correlated with coronary incidence explaining 65–85% of the variation among populations (67% in women and 86% in men). This large contribution to CAD incidence variation among populations might be a result of colinearity with several other common genetic and environmental factors. These results are not consistent with the cardiovascular Mediterranean paradox for genetics and support a CAD genetic architecture mainly based on combinations of common genetic polymorphisms. Population genetic risk scores is a promising approach in public health interventions to develop lifestyle programs and prevent intermediate risk factors in certain subpopulations with specific genetic predisposition. PMID:24806096

Carreras-Torres, Robert; Kundu, Suman; Zanetti, Daniela; Esteban, Esther

2014-01-01

117

The relationship between observer-based toxicity scoring and patient assessed symptom severity after treatment for head and neck cancer. A correlative cross sectional study of the DAHANCA toxicity scoring system and the EORTC quality of life questionnaires  

International Nuclear Information System (INIS)

Background and purpose: Morbidity is an important issue in cancer research. The observer-based toxicity scoring system used by DAHANCA (the Danish head and neck cancer study group) has proved itself sensitive to differences in toxicity in a large randomised study, but like other toxicity scoring systems it has not been formally validated. Conversely, the EORTC quality of life questionnaire (QLQ) has been validated as a tool for collecting information about the consequences of disease and treatment on the well being of cancer patients. The purpose of this study was to examine the relationship between the two methods of side effect recording. Patients and methods: One hundred and sixteen recurrence free patients with laryngeal (n=44), pharyngeal (n=34) and oral cavity (n=38) cancer attending follow-up after radiotherapy (n=83) or surgery (n=33) completed EORTC C30, the core questionnaire concerning general symptoms and function and EORTC H and N35 the head and neck specific questionnaire. The attending physicians in the follow-up clinic evaluated and recorded DAHANCA toxicity scores on the same patients. Results: The DAHANCA toxicity scoring system and the EORTC QLQ correlated with several clinical endpoints. The conceptually similar endpoints of the two methods correlated significantly. The objective endpoints of the DAHANCA scoring system were only correlated with quality of life endpoints to a very low degree. The DAHANCA toxicity scores had a low sensitivity (0.48-0icity scores had a low sensitivity (0.48-0.74) in detecting equivalent subjective complaints from the questionnaires and the observer-based scoring system severely underestimated patient complaints. A specific patient group where the DAHANCA score had a higher tendency to fail could not be detected. Conclusion: The DAHANCA toxicity score is an effective instrument in assessing objective treatment induced toxicity in head and neck cancer patients but insensitive and non-specific with regard to patient assessed subjective endpoints. This weakness seems inherent in an observer-based scoring system, and will probably also apply to newer ones like CTCAE 3.0

118

The relationship between observer-based toxicity scoring and patient assessed symptom severity after treatment for head and neck cancer. A correlative cross sectional study of the DAHANCA toxicity scoring system      and the EORTC quality of life questionnaires  

DEFF Research Database (Denmark)

BACKGROUND AND PURPOSE: Morbidity is an important issue in cancer       research. The observer-based toxicity scoring system used by DAHANCA (the       Danish head and neck cancer study group) has proved itself sensitive to       differences in toxicity in a large randomised study, but like other       toxicity scoring systems it has not been formally validated. Conversely,       the EORTC quality of life questionnaire (QLQ) has been validated as a tool       for collecting information about the consequences of disease and treatment       on the well being of cancer patients. The purpose of this study was to       examine the relationship between the two methods of side effect recording.       PATIENTS AND METHODS: One hundred and sixteen recurrence free patients       with laryngeal (n=44), pharyngeal (n=34) and oral cavity (n=38) cancer       attending follow-up after radiotherapy (n=83) or surgery (n=33) completed       EORTC C30, the core questionnaire concerning general symptoms and function       and EORTC H&N35 the head and neck specific questionnaire. The attending       physicians in the follow-up clinic evaluated and recorded DAHANCA toxicity       scores on the same patients. RESULTS: The DAHANCA toxicity scoring system       and the EORTC QLQ correlated with several clinical endpoints. The       conceptually similar endpoints of the two methods correlated       significantly. The objective endpoints of the DAHANCA scoring system were       only correlated with quality of life endpoints to a very low degree. The       DAHANCA toxicity scores had a low sensitivity (0.48-0.74) in detecting       equivalent subjective complaints from the questionnaires and the       observer-based scoring system severely underestimated patient complaints.       A specific patient group where the DAHANCA score had a higher tendency to       fail could not be detected. CONCLUSION: The DAHANCA toxicity score is an       effective instrument in assessing objective treatment induced toxicity in       head and neck cancer patients but insensitive and non-specific with regard       to patient assessed subjective endpoints. This weakness seems inherent in       an observer-based scoring system, and will probably also apply to newer       ones like CTCAE 3.0

Jensen, Kenneth; Jensen, Anders Bonde

2006-01-01

119

Modified Chrispin-Norman score: correlation with peak exercise capacity and efficiency of ventilation in children with cystic fibrosis.  

Science.gov (United States)

The modified Chrispin-Norman radiography score (CNS) is used in evaluation of radiographic changes in children with cystic fibrosis (CF). We evaluated the correlation of modified CNS with peak exercise capacity (Wpeak) and ventilatory efficiency (reflected by breathing reserve index-BRI) during progressive cardiopulmonary exercise testing (CPET). Thirty-six children aged 8-17 years were stratified according to their CNS into 3 groups: mild (15). CPET was performed on a cycle ergometer. Lung function tests included spirometry and whole-body plethysmography. Patients with higher CNS had lower FEV1 (p anaerobic threshold and at Wpeak was elevated in patients with the highest CNS values (p < .001). The modified CNS correlates moderately with Wpeak (R = -0.443; p = .007) and BRI (R = -0.419; p = .011). Stepwise multiple linear regression showed that RV/TLC was the best predictor of Wpeak/pred (%; B = -0.165; ? = -0.494; R2 = .244; p = .002). Children with CF who have high modified CNS exhibit decreased exercise tolerance and ventilatory inefficacy during progressive effort. PMID:25111160

Sovtic, Aleksandar; Minic, Predrag; Kosutic, Jovan; Markovic-Sovtic, Gordana; Gajic, Milan

2014-08-01

120

Lack of a correlation between micronucleus scores in cytokinesis - blocked lymphocytes and cancer patient response to radiotherapy  

International Nuclear Information System (INIS)

In the present study, we have used a retrospective approach in order to investigate a range of radiosensitivities measured by micronucleus (Mn) assay in lymphocytes of head and neck, and cervix cancer patients. There were treatment failures and tumor free patients in both groups. The aim therefore was to establish the possible role of MN scores in identifying these different responses. Peripheral blood samples were collected from 15 patients for head and neck cancer group, and from 16 patients for cervix group. The samples were irradiated with 3 Gy of Co-60 gamma irradiation. Micronucleus values which determine the cellular radiosensitivity ranged between 0.03 and 0.39 with the average value of 0.23 for head and neck cancer patients and ranged between 0.05 and 0.48 with the average value of 0.25. Statistically, there was no difference between radiosensitivity of two patients groups (p=0.33). In cervix cancer group, there were four treatment failure patients and there were six treatment failure patients in head and neck cancer group. MN frequencies of all the failure patients generated more micronuclei following in vitro test irradiation and were above the average sensitivity value of 0.25. The results in the present paper provide an evidence that although we investigated two different cancer groups, the quantitative similarities in the radiosensitivity range measured by MN assay exist. However, within the radiosensitivity range of each group, there was lack of a corree of each group, there was lack of a correlation between MN scores and patient response. It could be concluded that MN test applied to lymphocytes does not have a predictive value in patient prognosis. (authors)

 
 
 
 
121

Joint health scores in a haemophilia A cohort from Pakistan with minimal or no access to factor VIII concentrate: correlation with thrombin generation and underlying mutation.  

Science.gov (United States)

Haemophilia A is associated with recurrent joint bleeding which leads to synovitis and debilitating arthropathy. Coagulation factor VIII level is an important determinant of bleed number and development of arthropathy . The aim of this study was to compare the haemophilia joint health score (HJHS) and Gilbert score with severity, age, thrombin generation (TG) and underlying mutation in a haemophilia A cohort which had minimal access to haemostatic replacement therapy. Ninety-two haemophilia A individuals were recruited from Pakistan. Age, age at first bleed, target joints, haemophilic arthropathy joints, HJHS and Gilbert score were recorded. A strong correlation was found between HJHS and Gilbert score (r = 0.98), both were significantly higher in severe (n = 59) compared with non-severe (n = 29) individuals before the age of 12 years (P ? 0.01) but not thereafter. When individuals were divided according to developmental age (16 years), both HJHS and Gilbert score were significantly lower in the youngest group (P ? 0.001), there was no difference between 12-16 years and >16 years. In severe individuals there was no correlation between in vitro TG and joint score, whereas in non-severe individuals there was a weak negative correlation. In the severe group, no significant difference was observed for either joint score according to the underlying mutation type (inversion, missense, nonsense, frameshift). In this cohort of haemophilia A individuals with minimal access to haemostatic treatment, haemophilic arthropathy correlated with severity and age; among severe individuals, joint health scores did not relate to either the underlying mutation or in vitro TG. PMID:24354535

Khanum, F; Bowen, D J; Kerr, B C; Collins, P W

2014-05-01

122

Refining criteria for diagnosis of cutaneous infections caused by herpes viruses through correlation of morphology with molecular pathology  

Directory of Open Access Journals (Sweden)

Full Text Available BACKGROUND: Infections of the skin by herpes viruses do not always present themselves in typical fashion. Early diagnosis, however, is crucial for appropriate treatment. Polymerase chain reaction (PCR allows diagnosis and differential diagnosis of herpes virus infections, but the method is not yet available in large parts of the world, where diagnosis is made based on morphology alone. AIM: To refine criteria for the diagnosis of herpes virus infections of the skin by way of correlation of clinical and histopathologic findings with results of PCR studies. METHODS: We studied 75 clinically diagnosed patients of "zoster," "varicella," and "herpes simplex", to correlate clinical and histopathological findings with results of PCR studies on paraffin embedded biopsy specimens. RESULTS: Clinical suspicion of infection by herpes viruses was confirmed by histopathology in 37% of the cases and by PCR studies in 65% of the cases. Zoster was frequently misdiagnosed as infection with herpes simplex viruses (30%. When diagnostic signs of herpes virus infection were encountered histopathologically, PCR confirmed the diagnosis in 94%. By way of correlation with results of PCR studies, initial lesions of herpes virus infections could be identified to have a distinctive histopathological pattern. Herpetic folliculitis appeared to be a rather common finding in zoster, it occurring in 28% of the cases. CONCLUSION: We conclude that correlation of clinical and histopathological features with results of PCR studies on one and the same paraffin embedded specimen permits identification of characteristic morphologic patterns and helps to refine criteria for diagnosis both clinically and histopathologically.

Böer Almut

2006-01-01

123

Comparisons of bone mass measurements on various skeletal sites including quantitative ultrasonography of the calcaneus for assessing age-related losses, their correlations, and diagnostic agreement using the Japanese and WHO criteria for osteoporosis  

International Nuclear Information System (INIS)

The aim of this study was to compare age-related bone losses and correlations among several bone mass measurements and to evaluate diagnostic agreement among them using the Japanese and World Health Organization (WHO) criteria for osteoporosis. A total of 846 women (mean±standard deviation (SD): age 54±9 years) were evaluated. Bone mineral densities of the lumbar spine, femoral neck, and calcaneus were measured by dual X-ray absorptiometry and distal radius by peripheral computed tomography. Quantitative ultrasonography (QUS) parameters of the calcaneus were also measured. The age-related bone losses after 50 years of age and correlations among bone mass results were evaluated using linear regression analysis. Diagnostic agreement was evaluated by kappa statistics. The annual losses ranged from 1.0% to 1.6%. The correlation coefficients ranged from 0.54 to 0.78. The kappa scores ranged from 0.52 to 0.30 for all subjects using the Japanese criteria and from 0.38 to 0.15 using the WHO criteria. Bone mass measurements including QUS on various skeletal sites documented age-related changes similarly, and their bone masses correlated moderately. The diagnostic agreements among them were fair to poor. To screen out women with a risk of osteoporosis, it is important to choose which technique to use and which skeletal site to measure. (author)

124

Correlation between serum ferritin levels and attention-deficit/hyperactivity disorder symptom scores in children based on the Abbreviated Conners Teachers Rating Scale  

Directory of Open Access Journals (Sweden)

Full Text Available Background Dopamine deficiency is thought to be one of the factors causing attention-deficit /hyperactivity disorder (ADHD in children. Iron contributes to the regulation of dopamine neurotransmitter activity, thus, iron deficiency has been associated with ADHD. Several studies have been conducted in other countries to assess for a correlation between serum ferritin levels and ADHD symptom scores, but with varied results. Objective To examine the relationship between iron deficiency and ADHD symptoms, in particular the correlation between serum ferritin levels and Abbreviated Conners Teachers Rrating Scale (ACTRS scores in children with ADHD. Methods This cross-sectional study was performed in children aged 5-12 years who were newly diagnosed with ADHD. Subjects were recruited from the Klinik Anakku Kelapa Gading, the Neurology Outpatient Clinic, the Growth and Development-Social Pediatrics Clinic, and the Integrated Child Clinic of Cipto Mangunkusumo Hospital. ADHD diagnoses were established using Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSMm-IV. Subjects’ parents and teachers were asked to complete the ACTRS instrument sheet. Venous blood specimens were obtained for peripheral blood and serum ferritin level tests. Results Of the 33 subjects recruited, 23 were male. Subjects’ ages ranged from 5-12 years, with a median age of onset of 4 (range 2-10 years. The combined type of ADHD (with inattention and hyperactivity-impulsivity was more commonly found (20/33 in our subjects. The mean serum ferritin was 51.31 (SD 27.7 ng/mL. Using 20 ng/mL as the serum ferritin cutoff value, 5/33 subjects were considered to be iron deficient. Median ACTRS score by parents and teachers were 15 and 15, respectively. Higher scores were found in the combined type subject group than in the inattention type subject group. Mmedian serum ferritin levels of the two ADHD type groups were similar. ACTRS scores of parents and teachers tended to be higher in the iron-deficient group (16 and 16, respectively than in the normal serum iron group (14.5 and 12.5, respectively. Serum ferritin level showed no correlation (r=-0.243; P=0.086 to the parents’ ACTRS score, and no correlation (r=-.057; P=0.377 to the teachers’ ACTRrS score. Conclusion Serum ferritin level showed no correlation to ACTRS scores of parents and teachers, respectively. However, the median ACTRS score was higher in the iron-deficiency group than in the normal iron status group, suggesting that there may be a qualitative relationship between iron deficiency and ADHD symptoms.

Intan Alita Putri Tumbelaka

2014-10-01

125

Could near-infrared Raman spectroscopy be correlated with the METAVIR scores in liver lesions induced by hepatitis C virus?  

Science.gov (United States)

The liver is responsible for several basic functions in human body how the syntheses of the most main proteins and degradation process of toxins, drugs and alcohols. In present days, the viral hepatitis C is one of the highest causes of chronic hepatic illness worldwide, affecting around 3% of the world population. The liver biopsy is considered the gold standard for diagnosing hepatic fibrosis; however, the biopsies may be questioned because of potential sampling error, morbidity, possible mortality and relatively high costs. Spectroscopy techniques such as Raman spectroscopy have been used for diagnosis of human tissues, with favorable results. Raman spectroscopy has been employed to distinguish normal from hepatic lesions through spectral features mainly of proteins, nucleic acids and lipids. In this study, eleven patients with diagnoses of chronic hepatitis C underwent hepatic biopsies having two hepatic fragments collected: one was scored through METAVIR system and the other one was submitted to near-infrared Raman spectroscopy using a dispersive spectrometer (830 nm wavelength, 300 mW laser power and 20 s exposure time). Five spectra were collected in each fragment and submitted to Principal Components Analysis (PCA). Results showed a good correlation between the Raman spectroscopy features and the stage of hepatic fibrosis and inflammation. PCA showed that samples with higher degree of fibrosis presented higher amount of protein features (collagen), whereas samples of higher degree of inflammation presented higher features of hemoglobin, in accordance to the expected evolution of the chronic hepatitis. It has been found an important biomarker for the beginning of hepatic lesion (quinone) with a spectral feature at 1595 cm-1.

Gaggini, Marcio Cesar Reino; Navarro, Ricardo Scarparo; Stefanini, Aline Reis; Sano, Rubens Sato; Silveira, Landulfo

126

Correlation of CT angiographic pulmonary artery obstruction scores with right ventricular dysfunction and clinical outcome in patients with acute pulmonary embolism  

Energy Technology Data Exchange (ETDEWEB)

Objective: To correlate CTA pulmonary artery obstruction scores (OS) with right ventricular dysfunction (RVD) and clinical outcome in patients with acute pulmonary embolism (PE). Materials and methods: In a prospective study of 50 patients (66 ± 12.9 years) with PE pulmonary artery OS (Qanadli, Mastora, and Mastora central) were assessed by two radiologists. To assess RVD all patients underwent echocardiography within 24 h. Furthermore, RVD on CT was assessed by calculating the right ventricular/left ventricular (RV/LV) diameter ratios on transverse (RV/LVtrans) and four-chamber views (RV/LV4ch) as well as the RV/LV volume ratio (RV/LVvol). OS were correlated with RVD and the occurrence of adverse clinical outcomes (defined as death, need for intensive care treatment, or cardiac insufficiency ?NYHA III). Results: Mean Mastora, Qanadli, and Mastora central OS were 26.4 ± 17.7, 12.6 ± 9.9 and 7.5 ± 9, respectively. Echocardiography demonstrated moderate and severe RVD in 10 and 5 patients, respectively. Patients with moderate and severe RVD showed significantly higher Mastora central scores than patients without RVD (14 ± 10.8 vs. 5.9 ± 7.8 [p = 0.05]; 17.6 ± 13.2 vs. 5.9 ± 7.8 [p = 0.038]). A relevant correlation (i.e. r ? 0.6) between OS and CT parameters for RVD were only found for the Mastora score and the Mastora central score (RV/LV4ch: r = 0.61 and 0.68, RV/LVvol: r = 0.61 and 0.6). 18 patients experienced an adverse clinical outcome. None of the OS differed significantly between patients with and without adverse clinical outcome. Conclusion: Pulmonary artery obstruction scores can differentiate between patients with and without RVD. However, in this study, obstruction scores were not correlated to adverse clinical outcome.

Apfaltrer, P., E-mail: paul.apfaltrer@medma.uni-heidelberg.de [Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim (Germany); Henzler, T.; Meyer, M. [Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim (Germany); Roeger, S.; Haghi, D.; Gruettner, J.; Süselbeck, T. [Department of Internal Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim (Germany); Wilson, R.B.; Schoepf, U.J. [Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Drive, MSC 226, Charleston, SC 29401 (United States); Schoenberg, S.O.; Fink, C. [Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim (Germany)

2012-10-15

127

Correlation of CT angiographic pulmonary artery obstruction scores with right ventricular dysfunction and clinical outcome in patients with acute pulmonary embolism  

International Nuclear Information System (INIS)

Objective: To correlate CTA pulmonary artery obstruction scores (OS) with right ventricular dysfunction (RVD) and clinical outcome in patients with acute pulmonary embolism (PE). Materials and methods: In a prospective study of 50 patients (66 ± 12.9 years) with PE pulmonary artery OS (Qanadli, Mastora, and Mastora central) were assessed by two radiologists. To assess RVD all patients underwent echocardiography within 24 h. Furthermore, RVD on CT was assessed by calculating the right ventricular/left ventricular (RV/LV) diameter ratios on transverse (RV/LVtrans) and four-chamber views (RV/LV4ch) as well as the RV/LV volume ratio (RV/LVvol). OS were correlated with RVD and the occurrence of adverse clinical outcomes (defined as death, need for intensive care treatment, or cardiac insufficiency ?NYHA III). Results: Mean Mastora, Qanadli, and Mastora central OS were 26.4 ± 17.7, 12.6 ± 9.9 and 7.5 ± 9, respectively. Echocardiography demonstrated moderate and severe RVD in 10 and 5 patients, respectively. Patients with moderate and severe RVD showed significantly higher Mastora central scores than patients without RVD (14 ± 10.8 vs. 5.9 ± 7.8 [p = 0.05]; 17.6 ± 13.2 vs. 5.9 ± 7.8 [p = 0.038]). A relevant correlation (i.e. r ? 0.6) between OS and CT parameters for RVD were only found for the Mastora score and the Mastora central score (RV/LV4ch: r = 0.61 and 0.68, RV/LVvol: r = 0.61 and 0.6). 18 patients experienced an adverse clinical outcome. None of the OS differed significantly between patients with and without adverse clinical outcome. Conclusion: Pulmonary artery obstruction scores can differentiate between patients with and without RVD. However, in this study, obstruction scores were not correlated to adverse clinical outcome

128

Correlation between Bhalla score and spirometry in children and adolescents with Cystic Fibrosis / Correlação entre escore de Bhalla e espirometria em crianças e adolescentes com fibrose cística  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in portuguese Objetivo: correlacionar os achados da tomografia computadorizada de alta resolução (TCAR) do tórax, com base no escore de Bhalla, com os dados clínicos e a espirometria em crianças e adolescentes com fibrose cística (FC), além de estudar a concordância entre dois médicos radiologistas para o escor [...] e de Bhalla e suas categorias. Métodos: foram avaliados os prontuários e os exames de 23 pacientes do ambulatório. Os itens avaliados foram idade, peso, altura, escore Z altura/idade, escore Z peso/ idade, índice de massa corpórea (IMC), saturação de O2, espirometria e escore de Bhalla. Resultados: os pacientes avaliados tinham média de idade de 17,4±5,7 anos, sendo 15 do sexo feminino e 8 do sexo masculino. Houve boa correlação entre o escore de Bhalla e a espirometria (CVF-r = 0,718, p 70% já apresentavam alterações na nota final do escore de Bhalla. Na análise da concordância entre os examinadores, foi encontrado coeficiente kappa de 0,81 (p Abstract in english Objective: to correlate the findings of high resolution computed tomography of the chest based on the Bhalla score with the clinical data and spirometry in children and adolescents with cystic fibrosis, and to study the concordance between two radiologists for the Bhalla score and its categories. [...] Methods: we evaluated the medical records of 23 patients from the outpatient clinic. The items evaluated included age, weight, height, height/age Z-score, weight/age Z-score, body mass index (BMI), O2 saturation, spirometry and Bhalla score. Results: the patients had a mean age of 17.4 years ± 5.7 years, with fifteen females and eight males. There was good correlation between Bhalla score and spirometry (FVC-r =0.718, p 70% already had changes in their final Bhalla score. In the analysis of the concordance between the examiners a Kappa coefficient of 0.81 (p

Flavia Fajardo Linhares, Pereira; Cassio da Cunha, Ibiapina; Cristina Gonçalves, Alvim; Paulo Augusto Moreira, Camargos; Reginaldo, Figueiredo; Jesiana Ferreira, Pedrosa.

2014-06-01

129

Correlation between Bhalla score and spirometry in children and adolescents with Cystic Fibrosis / Correlação entre escore de Bhalla e espirometria em crianças e adolescentes com fibrose cística  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in portuguese Objetivo: correlacionar os achados da tomografia computadorizada de alta resolução (TCAR) do tórax, com base no escore de Bhalla, com os dados clínicos e a espirometria em crianças e adolescentes com fibrose cística (FC), além de estudar a concordância entre dois médicos radiologistas para o escor [...] e de Bhalla e suas categorias. Métodos: foram avaliados os prontuários e os exames de 23 pacientes do ambulatório. Os itens avaliados foram idade, peso, altura, escore Z altura/idade, escore Z peso/ idade, índice de massa corpórea (IMC), saturação de O2, espirometria e escore de Bhalla. Resultados: os pacientes avaliados tinham média de idade de 17,4±5,7 anos, sendo 15 do sexo feminino e 8 do sexo masculino. Houve boa correlação entre o escore de Bhalla e a espirometria (CVF-r = 0,718, p 70% já apresentavam alterações na nota final do escore de Bhalla. Na análise da concordância entre os examinadores, foi encontrado coeficiente kappa de 0,81 (p Abstract in english Objective: to correlate the findings of high resolution computed tomography of the chest based on the Bhalla score with the clinical data and spirometry in children and adolescents with cystic fibrosis, and to study the concordance between two radiologists for the Bhalla score and its categories. [...] Methods: we evaluated the medical records of 23 patients from the outpatient clinic. The items evaluated included age, weight, height, height/age Z-score, weight/age Z-score, body mass index (BMI), O2 saturation, spirometry and Bhalla score. Results: the patients had a mean age of 17.4 years ± 5.7 years, with fifteen females and eight males. There was good correlation between Bhalla score and spirometry (FVC-r =0.718, p 70% already had changes in their final Bhalla score. In the analysis of the concordance between the examiners a Kappa coefficient of 0.81 (p

Flavia Fajardo Linhares, Pereira; Cassio da Cunha, Ibiapina; Cristina Gonçalves, Alvim; Paulo Augusto Moreira, Camargos; Reginaldo, Figueiredo; Jesiana Ferreira, Pedrosa.

130

CORRELATION OF PEMPHIGUS VULGARIS ANTIBODY TITERS BY INDIRECT IMMUNOFLUORESCENCE WITH ACTIVITY OF DISEASE BASED ON PEMPHIGUS AREA AND ACTIVITY SCORE (PAAS  

Directory of Open Access Journals (Sweden)

Full Text Available Indirect immunofluorescence (IIF has been used to identify and measure autoantibody levels in pemphigus vulgaris but data about relationship between clinical severity of disease and antibody titers by IIF have been conflicting. We conducted this cross-sectional study to correlate the severity of oral and/or cutaneous involvement in patients with pemphigus vulgaris based on Pemphigus Area and Activity Score with IIF titers. Sixty-one new pemphigus vulgaris patients were included in this study. Human prepuce was used as substrate for IIF and assessment of disease severity was based on Pemphigus Area and Activity Score. The mean±SD age was 44.04±30.46 years, with a range of 18 to 79 years. IIF was positive in 56 (91.8% patients. There was a significant relationship between total disease score and IIF titers ((P<0.001. Also a significant relationship was found between skin score (P=0.04 and mucosal score (P=0.04 with IIF titers. Our results show that there is a significant relationship between disease activity based on Pemphigus Area and Activity Score and antibody titers by IIF. Further studies are recommended to determine the usefulness of this technique for monitoring disease.

H. Mortazavi

2008-06-01

131

A correlation between characteristics and students’ perception with the last score of field experience study at community based medicine  

Directory of Open Access Journals (Sweden)

Full Text Available Field experience study (FES is one of the Community Based Medicine Education Programs that has done in Faculty of Medicine University of Malahayati. The aims of this study were to identify several factors related to final FES score. The questionnaires were given for all field study participants. It consisted of students’ characteristics and perception on field study. This FES was conducted on 3 September 2007. Cox regression was used to analyze data using STATA version 9.0. Gender, previous GPA, time of taking FES was dominant risk factors related to risk of FES score. The students who had higher cumulative Grade Point Average (GPA had 72% higher on final FES score [adjusted relative risk (RR? = 1.72; 95% Confidence interval (CI = 1.22-2.43. Female than male students had 39% higher final FES score (RR? = 1.39; 95% CI = 0.93-2.09; P = 0.111, and the students who took than who did not take FES on recommended year of study had 29% higher final FES score (RR = 1.29; 95% CI = 0.96-1.73; P = 0.088. While conducting FES, special attention should be given to students who had previous GPA in order to increase their final FES score. (Med J Indones 2008; 17: 64-7Keywords: community-based medicine, field experience study, student’s performance

Marisa Anggraini

2008-02-01

132

Combination of scoring schemes for protein docking  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Docking algorithms are developed to predict in which orientation two proteins are likely to bind under natural conditions. The currently used methods usually consist of a sampling step followed by a scoring step. We developed a weighted geometric correlation based on optimised atom specific weighting factors and combined them with our previously published amino acid specific scoring and with a comprehensive SVM-based scoring function. Results The scoring with the atom specific weighting factors yields better results than the amino acid specific scoring. In combination with SVM-based scoring functions the percentage of complexes for which a near native structure can be predicted within the top 100 ranks increased from 14% with the geometric scoring to 54% with the combination of all scoring functions. Especially for the enzyme-inhibitor complexes the results of the ranking are excellent. For half of these complexes a near-native structure can be predicted within the first 10 proposed structures and for more than 86% of all enzyme-inhibitor complexes within the first 50 predicted structures. Conclusion We were able to develop a combination of different scoring schemes which considers a series of previously described and some new scoring criteria yielding a remarkable improvement of prediction quality.

Schomburg Dietmar

2007-08-01

133

Entorhinal cortex volume measured with 3T MRI is positively correlated with the Wechsler memory scale-revised logical/verbal memory score for healthy subjects  

Energy Technology Data Exchange (ETDEWEB)

Previous studies revealed a correlation between local brain volume and cognitive function. The aim of the present study was to investigate the correlation between local gray matter volume and the Wechsler Memory Scale-Revised (WMS-R) logical/verbal memory (WMS-R-verbal) score in healthy adults using a 3 Tesla magnetic resonance scanner and voxel-based morphometry (VBM). T1-weighted magnetic resonance images were obtained in 1,169 healthy adults. The T1-weighted images in native space were bias-corrected, spatially normalized, and segmented into gray matter, white matter, and cerebrospinal fluid images with Statistical Parametric Mapping 5. To investigate regionally the specific effects of the WMS-R-verbal score on the gray matter images, simple regression analysis was performed by VBM treating age, total intracranial volume, and gender as confounding covariates. A P value of less than 0.05 corrected with false discovery rate in voxel difference was considered to be statistically significant. Our study showed a significant positive correlation between the WMS-R-verbal score and the bilateral entorhinal cortex volume. In the right entorhinal, T value is 4.75, and the size of the clusters is 155 voxels. In the left entorhinal, T value is 4.08, and the size of the clusters is 23 voxels. A significant negative correlation was not found. To our knowledge, this is the first VBM study showing that entorhinal cortex volume is positively correlated with the WMS-R-verbal score for healthy subjects. Therefore, in our structural neuroimaging study, we add evidence to the hypothesis that the entorhinal cortex is involved in verbal memory processing. (orig.)

Goto, Masami [University of Tokyo Hospital, Department of Radiological Technology, Graduate School of Medicine, Tokyo (Japan); Kanazawa University, Tsunomatyou, Graduate School of Medical Science, Kanazawa (Japan); Abe, Osamu; Takao, Hidemasa; Inano, Sachiko; Mori, Harushi; Kunimatsu, Akira; Ohtomo, Kuni [University of Tokyo Hospital, Department of Radiology, Tokyo (Japan); Miyati, Tosiaki [Kanazawa University, Tsunomatyou, Graduate School of Medical Science, Kanazawa (Japan); Yoshikawa, Takeharu; Hayashi, Naoto [University of Tokyo Hospital, Department of Computational Diagnostic Radiology and Preventive Medicine, Tokyo (Japan); Kabasawa, Hiroyuki [GE Healthcare, Japan Applied Science Laboratory, Hino (Japan); Aoki, Shigeki [Juntendo University, Department of Radiology, Tokyo (Japan); Ino, Kenji; Iida, Kyouhito; Yano, Keiichi [University of Tokyo Hospital, Department of Radiological Technology, Graduate School of Medicine, Tokyo (Japan)

2011-08-15

134

Correlation between IQIs- criteria of utilization from the level of required sensitivity  

International Nuclear Information System (INIS)

The correct selection and utilization of the image quality indicators (IQI) is indispensable to assure the detection and allow the dimensioning of the gaps in the radiographic test. Its use by the industries lead to an inadequate use of IQI, distortioning the specifications adopted. From this observations the authors show the essentials parameters of IQIs in a way to facilitate, without quality damage or distortion of specifications, the correlation among the several types. (E.G.)

135

Correlation of Revised Trauma Score with Mortality Rate of Traumatic Patients within the First 24 hours of Hospitalization  

Directory of Open Access Journals (Sweden)

Full Text Available Background: Trauma is a major health problem throughout the world, leading to death and disability especially in the first four decades of victims’ life. In Iran also, accident-related death has a critical situation with an increasing rate of 10-15% per year. The aim of this study was to determine the relationship between revised trauma score and mortality rate of traumatic patients within the first 24 h of hospitalization. Materials and Methods: A prospective cross-sectional study was conducted to investigate the association between revised trauma score and the mortality rate of traumatic patients within the first 24 h of hospitalization on 240 traumatic patients admitted to Khatam al-Anbia hospital. The obtained data were analyzed with SPSS software-15, using logistic regression, chi-square, and descriptive statistics. Results: Seventy four point tow percent of patients were referred due to accident, of which 38.3% had multiple traumas. Fifty point eight percent of traumatic patients died within the first 24 h of hospitalization. The minimum and maximum revised trauma score in injured patients were 7 and 12, respectively. Also, 80% of mortality was seen in victims with a score of 9-10. Both the ?2 test and logistic regression showed a significant relationship between the first revised trauma score and the mortality rate of traumatic patients within the first 24 h of hospitalization (p=0.001. Conclusion: The results of this study indicate that the revised trauma score can be used as a tool to predict the mortality rate of traumatic patients.

Nastaran Heydari-Khayat

2014-12-01

136

Do Standardized Tests Penalize Deep-Thinking, Creative, or Conscientious Students?: Some Personality Correlates of Graduate Record Examinations Test Scores  

Science.gov (United States)

The objective of the study reported here was to explore the relationship of Graduate Record Examinations (GRE) General Test scores to selected personality traits--conscientiousness, rationality, ingenuity, quickness, creativity, and depth. A sample of 342 GRE test takers completed short personality inventory scales for each trait. Analyses…

Powers, Donald E.; Kaufman, James C.

2004-01-01

137

Correlation between mental health co?morbidity screening scores and clinical response in collaborative care treatment for depression  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The hypothesis for this paper is that adult patients who have higher screening scores for mental health co?morbidities and depression have a greater likelihood of not responding to treatment with collaborative care management (CCM) for their depression within six months.

Angstman, Kurt B.; Dejesus, Ramona S.; Rohrer, James E.

2010-01-01

138

Segmented corpus callosum diffusivity correlates with the Expanded Disability Status Scale score in the early stages of relapsing-remitting multiple sclerosis  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in english OBJECTIVE: The aim of this study was to characterize the microscopic damage to the corpus callosum in relapsing-remitting multiple sclerosis (RRMS) with diffusion tensor imaging and to investigate the correlation of this damage with disability. The diffusion tensor imaging parameters of fractional [...] anisotropy and mean diffusivity provide information about the integrity of cell membranes, offering two more specific indices, namely the axial and radial diffusivities, which are useful for discriminating axon loss from demyelination. METHOD: Brain magnetic resonance imaging exams of 30 relapsing-remitting multiple sclerosis patients and 30 age- and sex-matched healthy controls were acquired in a 3T scanner. The axial diffusivities, radial diffusivities, fractional anisotropy, and mean diffusivity of five segments of the corpus callosum, correlated to the Expanded Disability Status Scale score, were obtained. RESULTS: All corpus callosum segments showed increased radial diffusivities and mean diffusivity, as well as decreased fractional anisotropy, in the relapsing-remitting multiple sclerosis group. The axial diffusivity was increased in the posterior midbody and splenium. The Expanded Disability Status Scale scores correlated more strongly with axial diffusivities and mean diffusivity, with an isolated correlation with radial diffusivities in the posterior midbody of the corpus callosum. There was no significant correlation with lesion loads. CONCLUSION: Neurological dysfunction in relapsing-remitting multiple sclerosis can be influenced by commissural disconnection, and the diffusion indices of diffusion tensor imaging are potential biomarkers of disability that can be assessed during follow-up.

Carolina de Medeiros, Rimkus; Thiago de Faria, Junqueira; Dagoberto, Callegaro; Maria Concepcion Garcia, Otaduy; Claudia da Costa, Leite.

1115-11-01

139

Segmented corpus callosum diffusivity correlates with the Expanded Disability Status Scale score in the early stages of relapsing-remitting multiple sclerosis  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in english OBJECTIVE: The aim of this study was to characterize the microscopic damage to the corpus callosum in relapsing-remitting multiple sclerosis (RRMS) with diffusion tensor imaging and to investigate the correlation of this damage with disability. The diffusion tensor imaging parameters of fractional [...] anisotropy and mean diffusivity provide information about the integrity of cell membranes, offering two more specific indices, namely the axial and radial diffusivities, which are useful for discriminating axon loss from demyelination. METHOD: Brain magnetic resonance imaging exams of 30 relapsing-remitting multiple sclerosis patients and 30 age- and sex-matched healthy controls were acquired in a 3T scanner. The axial diffusivities, radial diffusivities, fractional anisotropy, and mean diffusivity of five segments of the corpus callosum, correlated to the Expanded Disability Status Scale score, were obtained. RESULTS: All corpus callosum segments showed increased radial diffusivities and mean diffusivity, as well as decreased fractional anisotropy, in the relapsing-remitting multiple sclerosis group. The axial diffusivity was increased in the posterior midbody and splenium. The Expanded Disability Status Scale scores correlated more strongly with axial diffusivities and mean diffusivity, with an isolated correlation with radial diffusivities in the posterior midbody of the corpus callosum. There was no significant correlation with lesion loads. CONCLUSION: Neurological dysfunction in relapsing-remitting multiple sclerosis can be influenced by commissural disconnection, and the diffusion indices of diffusion tensor imaging are potential biomarkers of disability that can be assessed during follow-up.

Carolina de Medeiros, Rimkus; Thiago de Faria, Junqueira; Dagoberto, Callegaro; Maria Concepcion Garcia, Otaduy; Claudia da Costa, Leite.

140

WHO-histological criteria for myeloproliferative neoplasms: reproducibility, diagnostic accuracy and correlation with gene mutations and clinical outcomes.  

Science.gov (United States)

Bone marrow histology is included in the diagnostic criteria of myeloproliferative neoplasms (MPNs). However, some concerns have emerged about its reproducibility. To evaluate the diagnostic accuracy of histology and to assess its correlation with presence of mutations and clinical outcomes, two pathologists reviewed the bone marrow biopsies corresponding to 211 patients with MPN. Despite the low agreement in the evaluation of individual histopathological characteristics, the concordance among pathologists when establishing the diagnosis was good (Kappa index 0·67). The specificity of histology was 100%, 98·5% and 98% in polycythaemia vera (PV), essential thrombocythaemia (ET) and primary myelofibrosis (PMF), respectively, whereas the sensitivity of histological diagnosis was low in PV and ET (32·5% and 54% respectively) and acceptable in PMF (75%). Thirteen out of 146 (9%) patients with clinical ET were diagnosed as prefibrotic PMF. No histological agreement or MPN otherwise unspecified was more frequently observed in JAK2 V617F-positive ET than in CALR-mutated cases, whereas megakaryocytic abnormalities and prefibrotic PMF were more frequently observed in CALR-mutated ET. In conclusion, histological criteria of MPN have a limited diagnostic accuracy due to low sensitivity. Patients with JAK2 V617F-positive MPN have a heterogeneous histology while CALR-positive ET is associated with megakaryocyte abnormalities and prefibrotic PMF. PMID:24957246

Alvarez-Larrán, Alberto; Ancochea, Agueda; García, Mar; Climent, Fina; García-Pallarols, Francesc; Angona, Anna; Senín, Alicia; Barranco, Carlos; Martínez-Avilés, Luz; Serrano, Sergio; Bellosillo, Beatriz; Besses, Carlos

2014-09-01

 
 
 
 
141

Diagnostic yield of MRI for audiovestibular dysfunction using contemporary referral criteria: correlation with presenting symptoms and impact on clinical management  

International Nuclear Information System (INIS)

Aim: To investigate the diagnostic yield of T2-weighted magnetic resonance imaging (MRI) screening for vestibular schwannoma and other relevant conditions in the setting of audiovestibular symptoms, given the more liberal contemporary referral criteria. To determine whether presenting clinical symptoms correlate with imaging outcome in order to guide future protocols for MRI referral. Materials and methods: Eight hundred and eighty-one consecutive MRI examinations performed in patients with audiovestibular dysfunction were reviewed. Clinical indications and findings were recorded. Case notes were reviewed in patients with positive imaging findings. Two-way, cross-tabulation, Chi-square analysis was performed to assess the relationship between presenting symptoms and imaging outcome. Results: Twelve of the 881 (1.4%) were positive for vestibular schwannoma. A further four of 881 (0.4%) revealed other relevant conditions. Incidental conditions, felt to be irrelevant to the presenting symptoms, were noted in 12 of the 881 (1.4%). In all 12 cases that were positive for vestibular schwannoma, either tinnitus or hearing loss was present. Conclusion: The yield for T2-weighted MRI to diagnose vestibular schwannoma and other relevant retrocochlear conditions was lower than for previous studies, which is likely to reflect trends in referral criteria. No single audiovestibular symptom or combination of symptoms is a statistically significant predictor of imaging outcome

142

Diagnostic yield of MRI for audiovestibular dysfunction using contemporary referral criteria: correlation with presenting symptoms and impact on clinical management  

Energy Technology Data Exchange (ETDEWEB)

Aim: To investigate the diagnostic yield of T2-weighted magnetic resonance imaging (MRI) screening for vestibular schwannoma and other relevant conditions in the setting of audiovestibular symptoms, given the more liberal contemporary referral criteria. To determine whether presenting clinical symptoms correlate with imaging outcome in order to guide future protocols for MRI referral. Materials and methods: Eight hundred and eighty-one consecutive MRI examinations performed in patients with audiovestibular dysfunction were reviewed. Clinical indications and findings were recorded. Case notes were reviewed in patients with positive imaging findings. Two-way, cross-tabulation, Chi-square analysis was performed to assess the relationship between presenting symptoms and imaging outcome. Results: Twelve of the 881 (1.4%) were positive for vestibular schwannoma. A further four of 881 (0.4%) revealed other relevant conditions. Incidental conditions, felt to be irrelevant to the presenting symptoms, were noted in 12 of the 881 (1.4%). In all 12 cases that were positive for vestibular schwannoma, either tinnitus or hearing loss was present. Conclusion: The yield for T2-weighted MRI to diagnose vestibular schwannoma and other relevant retrocochlear conditions was lower than for previous studies, which is likely to reflect trends in referral criteria. No single audiovestibular symptom or combination of symptoms is a statistically significant predictor of imaging outcome.

Vandervelde, C. [Department of Radiology, Guy' s and St Thomas' NHS Foundation Trust (United Kingdom)], E-mail: clivevandervelde@gmail.com; Connor, S.E.J. [Department of Radiology, Guy' s and St Thomas' NHS Foundation Trust (United Kingdom); Department of Neuroradiology, King' s College Hospital NHS Foundation Trust, London (United Kingdom)

2009-02-15

143

Apgar Scores  

Science.gov (United States)

... and Beyond > Apgar Scores Ages & Stages Listen Apgar Scores Article Body As soon as your baby is ... the womb. Each characteristic is given an individual score; two points for each of the five categories ...

144

Analysis of genetic correlations between multivariate measures of lactation persistency and somatic cell score in Italian Simmental cattle  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Genetic relationships between lactation curve traits and Somatic Cell Count are of great interest for dairy cattle breeding. Factor Analysis (MFA) and Principal Component Analysis (PCA) can be used to extract from the correlation matrix of milk test day records new unobservable (latent) variables that can be related to lactation curve shape. Previous researches report that MFA is particularly able to extract two latent variables related with level of production in early lactation ...

Vicario, Daniele; Steri, Roberto; Cappio Borlino, Aldo; Macciotta, Nicolo? Pietro Paolo

2007-01-01

145

[A study from Navarra. Hyperlipidemias. Avarage scores and percentiles for lipids and lipoproteins in a population of children and adolescents. Correlation with anthropometric parameters].  

Science.gov (United States)

As part of an epidemiological study on cardiovascular risk factors among children and adolescents in Navarra, the following parameters: total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides and C/HDL and LDL/HDL risk quotients were determined in 5,829 children. These children, of both sexes and between the ages of 4 and 17 years, were selected at random from the school population in our community. Average values and percentiles of these parameters were obtained for each group according to age and sex as a previous step to define the health condition or "lipid risk" in our population. When determining the correlation of these biochemical parameters with the anthropometrical parameters of BP, age, weight, height, Quetelet Index, body mass surface, skinfold thickness and the percentage of subcutaneous fat (after the necessary logarithmic transformations, adjusted to each age and sex group by Z-scores) we find that none of the correlation coefficients are significant. The triglycerides and the HDL-cholesterol have a low, but significant. The triglycerides and the HDL-cholesterol have a low, but significantly, correlation with the other lipid parameters. The lipid risk quotient (C/HDL, LDL/HDL) shows a higher correlation with LDL-cholesterol than with total cholesterol. PMID:8480942

Elcarte López, R; Villa-Elizaga, I; Sada Goñi, J; Gasco Eguiluz, M; Oyarzábal Irigoyen, M; Sola Mateos, A; García Ibero, C; Elcarte López, T; Ferrer Giménez, M; Fontaneda Estíbaliz, A

1993-04-01

146

Assessment of the metabolic flow phenotype of primary colorectal cancer: correlations with microvessel density are influenced by the histological scoring method  

International Nuclear Information System (INIS)

To investigate how the histological scoring of microvessel density affects correlations between integrated 18F-FDG-PET/perfusion CT parameters and CD105 microvessel density. A total of 53 patients were enrolled from 2007 to 2010. Integrated 18F-FDG-PET/perfusion CT was successful in 45 patients, 35 of whom underwent surgery without intervening treatment. Tumour SUVmax, SUVmean and regional blood flow (BF) were derived. Immunohistochemical staining for CD105 expression and analysis were performed for two hot spots, four hot spots and the Chalkley method. Correlations between metabolic flow parameters and CD105 expression were assessed using Spearman's rank correlation. Mean (SD) for tumour size was 38.5 (20.5) mm, for SUVmax, SUVmean and BF it was 19.1 (4.5), 11.6 (2.5) and 85.4 (40.3) mL/min/100 g tissue, and for CD105 microvessel density it was 71.4 (23.6), 66.8 (22.9) and 6.18 (2.07) for two hot spots, four hot spots and the Chalkley method, respectively. Positive correlation between BF and CD105 expression was modest but higher for Chalkley than for four hot spots analysis (r = 0.38, P = 0.03; r = 0.33, P = 0.05, respectively). There were no significant correlations between metabolic parameters (SUVmax or SUVmean) and CD105 expression (r = 0.08-0.22, P = 0.21-0.63). The histological analysis method affects correlations between tumour CD105 expression and BF but not SUVmax or SUVmean. (orig.)

147

Correlación entre índices de bioimpedancia eléctrica y score Apache II en pacientes con shock séptico / Correlation between indexes of electrical bioimpedance and Apache II score in patients with septic shock  

Scientific Electronic Library Online (English)

Full Text Available SciELO Peru | Language: Spanish Abstract in spanish Objetivo: Determinar la correlación entre diversos índices de bioimpedancia eléctrica (IBE) y el score APACHE II (sAII) en pacientes con shock séptico. Material y métodos: Se incluyeron 30 pacientes >14 años con shock séptico de la unidad de cuidados intensivos (UCI) adultos del Hospital Nacional Ca [...] yetano Heredia-Perú a quienes se calculó el (sAII) y se midió el ángulo de fase, índice de impedancia y relación LIC/LEC, correlacionándolos posteriormente mediante Pearson y regresión lineal múltiple. Resultados: El 60% fueron varones, la edad promedio fue 60 ± 20,92 años, talla 1,61 ± 0,06m, peso 65,46 ± 8,7 Kg. y tiempo de ingreso a UCI 8,4 ± 5,99 horas. El 86,6% requirió ventilación mecánica, el foco infeccioso más frecuente fue respiratorio (63,3%). El promedio del sAII fue 18,83 ± 9,23, la permanencia en UCI 8,4 ± 5,99 días y la letalidad al mes 50%. Solamente se encontró correlación negativa con significancia estadística (r = -0,46; p = 0,01) entre el ángulo de fase (AF) y el (sAII). Ni el índice de impedancia ni la relación LIC/LEC tuvieron correlación significativa. El mejor predictor de mortalidad fue el AF: todos los que fallecieron tuvieron un AF Abstract in english Objective: Objective: To determine the correlation between various indexes of bioelectrical impedance (IBE) and APACHE II score (sAII) in patients with septic shock. Material and methods: We included 30 patients > 14 years old with septic shock admitted to the Adults intensive care unit (ICU) at the [...] Hospital Nacional Cayetano Heredia – Peru. The (sAII) was calculated and various IBE parameters were measured (phase angle, impedance index and relationship ICF/ECF). Correlations were calculated by multiple linear regression and Pearson. Results: 60% were male, mean age was 60 ± 20.92 years, height 161 ± 6 cm, weight 65.46 ± 8.7 kg and time of admission ICU was 8.4 ± 5.99 hours. 86.6% required mechanical ventilation, the most common infection was respiratory in origin (63.3%). The mean sAII was 18.8 ± 9.2, ICU stay was 8.4 ± 5.99 days and mortality was 50% per month. We only found a statistically significant negative correlation (r = - 0.46, p = 0.01) between the phase angle (FA) and (sAII). Neither the impedance index nor the relationship ICF/ECF had significant correlation. The best predictor of mortality was FA: those who died had an FA

Manuel, Díaz-De Los Santos; Javier, Cieza; Raúl, Valenzuela.

2010-07-01

148

Heritabilities and genetic correlations of body condition score and muscularity with productive traits and their trend functions in Italian Simmental cattle  

Directory of Open Access Journals (Sweden)

Full Text Available With the aim to study the genetics of energy and muscle balance in the Italian Simmental breed, the objectives of this study were: i the estimation of the genetic parameters for body condition score (BCS and muscularity (MU score; ii the estimation of genetic correlations of BCS and MU with productive traits; iii the estimation of the expected pattern of BCS and MU over lactation. A total of 47,839 records of first-parity lactating cows, collected from 1999 to 2007 in 2794 herds, were used. Two-trait animal models were analyzed using restricted maximum likelihood (REML procedures to estimate (covariance components. The expected patterns of BCS and MU along the lactation of first parity cows were estimated from the solutions of DIM fixed effect obtained from an univariate mixed model for both the traits. The heritability estimated was 0.18 for BCS, 0.38 for MU, and ranged from 0.13 to 0.18 for yield traits. The genetic correlations between BCS, MU and yield traits were negative (-0.17 to -0.63. The genetic correlation between BCS and MU was strongly positive (0.88, indicating that cows that genetically tend to have high BCS are more likely to have high values of MU. The genetic parameters estimated suggested that selection for BCS and MU in dual purpose breeds may be possible, and BCS may indirectly improve MU. The expected patterns for BCS and MU showed the trend of these two traits along the lactation and can help farmers in planning the best management of the lactating cows.

Alessandro Bagnato

2013-04-01

149

Non-invasive markers of atherosclerosis and their correlation with Framingham risk score in Indian patients with type 2 diabetes mellitus  

Directory of Open Access Journals (Sweden)

Full Text Available Background: India has been referred as the "diabetes capital of the world”. Diabetes mellitus (DM is widely accepted as a vascular disease leading to substantive increase in cardiovascular disease (CVD. Recently, there has been much interest in the relationship between arterial stiffness and cardiovascular disease. So this study was conducted to assess the risk of atherosclerosis in patients with DM. Aim: To investigate the relationship between non-invasive oscillometric methods that assesses subclinical atherosclerosis, and Framingham Risk Score (FRS, an independent predictor of CVD, in patients with type 2 DM, and age-matched hypertensive and healthy controls. Methods: The four study groups consisted of group A I; patients with diabetes mellitus (>5 years along with hypertension (n=55, group A II; newly diagnosed patients with DM without hypertension (n=28, group B I; patients with hypertension (n=31 and group B II; healthy controls (n=30. The participants were subjected to oscillometric measurements like arterial stiffness index (ASI, pulse wave velocity (PWV, and augmentation index (AIx. All these parameters were correlated with FRS. Results: The PWV, ASI, AIx as well as FRS of 30 yr risk of CVD were elevated in patients with DM compared to healthy controls. A significant correlation was observed between FRS, and PWV, ASI, and AIx. Conclusion: This study reveals that non-invasive oscillometric markers can be useful in early detection of early atherosclerosis in patients with type 2 DM.

Namrata B.K

2014-07-01

150

7 CFR 1739.17 - Scoring of applications.  

Science.gov (United States)

...following scoring criteria: (1) The rurality of the Project (up to 40 points... (b) Scoring criteria: (1) The rurality of the project —up to 40 points...criterion will be used to evaluate the rurality of the Community served by...

2010-01-01

151

7 CFR 3400.15 - Review criteria.  

Science.gov (United States)

...Criteria: Score 1-10 Weight factor Score X weight factor Comments 1. Overall scientific...considered low and a score of ten (10) will be considered high...selection criterion. A weighted factor is used for each...

2010-01-01

152

7 CFR 3401.17 - Review criteria.  

Science.gov (United States)

...Criteria: Score 1-10 Weight factor Score X weight factor Comments 1. Overall scientific...considered low and a score of ten (10) will be considered high...selection criterion. A weighted factor is used for each...

2010-01-01

153

A new scoring method with magnetic resonance imagings for prediction of the postoperative results in cervical myelopathy  

International Nuclear Information System (INIS)

An evaluating method that uses scoring of preoperative magnetic resonance imagings (MRI) (preoperative MRI cumulative score) was devised to predict the postoperative results of dilation of the spinal canal for cervical spondylotic myelopathy. The usefulness of the method is reported. The subjects were 38 patients, and the mean preoperative MRI cumulative score was 9.2 points. The coefficient of correlation between the score and the postoperative improvement rate according to the criteria for results of treatment for spondylotic cervical myelopathy of the neck (established by the Japanese Orthopaedic Association) was -0.462, a significantly negative correlation. (author)

154

Predicting occupational personality test scores.  

Science.gov (United States)

The relationship between students' actual test scores and their self-estimated scores on the Hogan Personality Inventory (HPI; R. Hogan & J. Hogan, 1992), an omnibus personality questionnaire, was examined. Despite being given descriptive statistics and explanations of each of the dimensions measured, the students tended to overestimate their scores; yet all correlations between actual and estimated scores were positive and significant. Correlations between self-estimates and actual test scores were highest for sociability, ambition, and adjustment (r = .62 to r = .67). The results are discussed in terms of employers' use and abuse of personality assessment for job recruitment. PMID:10654851

Furnham, A; Drakeley, R

2000-01-01

155

Score 2009  

Science.gov (United States)

Objectives/Purpose: The SCORE 2009 workshop has been conducted annually for the past eight years. This workshop brings together key program personnel and site coordinators, research nurses, data managers, and quality assurance officers from institutions

156

Correlação da técnica bottom turn com as notas atribuídas no surf de alto rendimento / Correlation of the bottom turn technique with the scores attributed in high performance surfing  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese As competições de surf no cenário mundial têm apresentado um alto e homogêneo nível de desempenho entre os atletas. Assim, atentou-se à hipótese de que o bottom turn (BT), curva na base da onda essencial para a construção de manobras subsequentes, pode afetar os resultados alcançados em baterias de [...] surf de alto rendimento. O estudo teve como objetivo quantificar o tempo que os atletas levam na execução de BT em suas ondas e correlacioná-lo com as notas atribuídas. A amostra foi composta por quatro eventos do World Tour de Surf, sendo avaliadas 4 baterias de cada evento, perfazendo um total de 16 baterias investigadas. A análise de cada BT foi realizada por meio do recurso de corte de vídeo disponível no programa Sony Vegas Pro 10.0. A análise estatística foi implementada no software SPSS 18.0, sendo calculado o coeficiente de correlação de Pearson, com nível de significância de p Abstract in english The surf contests worldwide have presented a high and homogeneous level of performance by the athletes. Thus, the hypothesis that the bottom turn (BT), curve on the base of the wave which is essential to the construction of subsequent maneuvers, might influence the results in high performance compet [...] itions. The objective of this study was to quantify the time taken in the execution of the BT by the athletes and correlate it to the scores awarded. The research sample was composed of four contests of the Surfing World Tour. Four heats of each contest were assessed, in a total of sixteen heats studied. The analysis of each BT was performed by using the video split feature available in the Sony Vegas Pro 10.0 software. The statistic analysis was performed with the software SPSS 18.0. The Pearson correlation coefficient was calculated with a significance level of p

Pedro Caetano, Souza; Marcos Augusto, Rocha; Juarez Vieira do, Nascimento.

157

Critical power concept adapted for the specific table tennis test: comparisons between exhaustion criteria, mathematical modeling, and correlation with gas exchange parameters.  

Science.gov (United States)

The purposes of this study were to determine and to compare the critical power concept adapted for the specific table tennis test (critical frequency - C F ) estimated from 5 mathematical models and using 2 different exhaustion criteria (voluntary and technical exhaustions). Also, it was an aim to assess the relationship between C F estimated from mathematical models and respiratory compensation point (RCP), peak oxygen uptake ( V?O (2PEAK)) and minimal intensity at which V?O (2PEAK) ( F V?O (2PEAK)) appears. 9 male table tennis players [18(1) years; 62.3(4.4) kg] performed the maximal incremental test and 3-4 exhaustive exercise bouts to estimate C F s (balls · min (-1)). The exhaustion time and C F obtained were independent of the exhaustion criteria. The C F from 3-parameter model [45.2(7.0)-voluntary, 43.2(5.6)-technical] was lower than C F estimated by linear 2-parameter models, frequency-time (-1) [53.5(3.6)-voluntary, 53.5(3.5)-technical] and total ball thrown-time [52.2(3.5)-voluntary, 52.2(3.5)-technical] but significantly correlated. C F values from 2 linear models were significantly correlated with RCP [47.4(3.4) balls · min (-1)], and C F values of the linear and nonlinear models were correlated with F V?O (2PEAK) [56.7(3.4) balls · min (-1)]. However, there were no significant correlations between C F values and V?O (2PEAK) [49.8(1.1)ml · kg (-1) · min (-1)]. The results were not modified by exhaustion criteria. The 2 linear and non-linear 2-parameter models can be used to estimate aerobic endurance in specific table tennis tests. PMID:21563021

Zagatto, A; Miranda, M F; Gobatto, C A

2011-07-01

158

A Comparison of Two Scoring Methods for an Automated Speech Scoring System  

Science.gov (United States)

This paper compares two alternative scoring methods--multiple regression and classification trees--for an automated speech scoring system used in a practice environment. The two methods were evaluated on two criteria: construct representation and empirical performance in predicting human scores. The empirical performance of the two scoring models…

Xi, Xiaoming; Higgins, Derrick; Zechner, Klaus; Williamson, David

2012-01-01

159

Walk Score  

Science.gov (United States)

If you're looking for a walkable community, is there a way to determine which neighborhood might be best for you? Interested parties might use the Walk Score to get a basic sense of nearby amenities, such as grocery stores, parks, restaurants, and so on. Visitors can type in a street address or neighborhood, and they can find out the location's cumulative Walk Score. Also, visitors can use the site to find out about potential nearby rental properties, if they are so inclined. This site is compatible with all operating systems.

2012-04-27

160

Validity of the Boston qualitative scoring system for the Rey-Osterrieth complex figure among depressed elderly patients.  

Science.gov (United States)

A recent qualitative scoring method for the Rey-Osterrieth Complex Figure (ROCF), the Boston Qualitative Scoring System (BQSS), purports to assess visuospatial organization, visual memory and executive function by using multiple series of scores with well-defined criteria. The first objective of this study was to determine whether the BQSS cores correlated with scores derived from the tradition Osterrieth scoring method and which method was more efficient at separating the diagnostics groups. The second objective was to correlate the BQSS executive scores to other nonverbal and verbal tests of executive function, working memory, processing speed, and episodic memory to determine what cognitive abilities the BQSS scores were measuring. The subjects, older depressed patients and healthy controls, were free of any clinical sign of incipient dementia or comorbid neurological disease. Their ROCF drawings were scored using both the Osterrieth and BQSS methods. The BQSS summary drawing scores correlated well with the Osterrieth summary scores for the copy and short-delay recall phases, the percent retained over the delay period and recognition. The BQSS executive scores for Planning, which included both copy and recall phases, correlated with Matrix Reasoning indicating that they assessed nonverbal reasoning but they did not correlate with other traditional executive tests. Planning also contributed to the separation of diagnostics groups and was the most effective score for predicting the percent of the ROCF retained over a short delay. The remaining executive scores did not show a pattern of correlations with other nonverbal executive or working memory scores that would satisfy concerns regarding their interpretation or internal validity when used in an older and/or depressed population. No differences emerged between the two scoring methods in their efficiency for predicting depression. PMID:15370382

Elderkin-Thompson, Virginia; Boone, Kyle B; Kumar, Anand; Mintz, Jim

2004-08-01

 
 
 
 
161

The Impact of Overreporting on MMPI-2-RF Substantive Scale Score Validity  

Science.gov (United States)

This study examined the impact of overreporting on the validity of Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF) substantive scale scores by comparing correlations with relevant external criteria (i.e., validity coefficients) of individuals who completed the instrument under instructions to (a) feign psychopathology…

Burchett, Danielle L.; Ben-Porath, Yossef S.

2010-01-01

162

The Influence of Therapist Variance on the Dependability of Therapists' Alliance Scores: A Brief Comment on "The Dependability of Alliance Assessments: The Alliance-Outcome Correlation Is Larger than You Think" (Crits-Christoph et al., 2011)  

Science.gov (United States)

Objective: Crits-Christoph, Connolly Gibbons, Hamilton, Ring-Kurtz, and Gallop (2011) used generalizability theory to critique the measurement of the therapeutic alliance in psychotherapy research, showing that the dependability of alliance scores may be quite low, which in turn can lead to attenuated alliance-outcome correlation estimates. Method…

Baldwin, Scott A.; Imel, Zac E.; Atkins, David C.

2012-01-01

163

Correlação dos escores de risco com a anatomia coronária na síndrome coronária aguda sem supra-ST / Correlation of risk scores with coronary anatomy in non-ST-elevation acute coronary syndrome  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese FUNDAMENTO:Há poucas publicações sobre a correlação entre escores de risco e anatomia coronária na síndrome coronária aguda (SCA). OBJETIVO: Correlacionar os escores de risco com a gravidade da lesão coronária na SCA sem supra-ST. MÉTODOS: Foram analisados 582 pacientes entre julho de 2004 e outubro [...] de 2006. Avaliou-se a correlação entre os escores de risco TIMI, GRACE hospitalar e em seis meses com lesão coronária > 50%, por método não paramétrico de Spearman. Modelo de regressão logística múltipla foi realizado para determinar a habilidade preditiva dos escores em discriminar quem terá ou não lesão coronária > 50%. RESULTADOS: Foram 319 (54,8%) homens e a média de idade era 59,9 (± 10,6) anos. Correlação positiva foi observada entre a pontuação dos escores de risco e lesão coronária > 50% (escore de risco TIMI r = 0,363 [p 50% foi: TIMI = 0,704 [IC95% 0,656-0,752; p Abstract in english BACKGROUND: The literature lacks studies regarding the correlation between risk scores and coronary anatomy in acute coronary syndrome (ACS) OBJECTIVE: Correlate risk scores with the severity of the coronary lesion in ACS with non-ST elevation. METHODS: A total of 582 patients were analyzed between [...] July 2004 and October 2006. The correlation between TIMI risk scores and GRACE (hospital and six months) scores was performed for patients with coronary lesion > 50%, using Spearman´s non-parametric method. Multiple regression logistics was used to determine the predictive ability of the scores to discriminate to discriminate who will have a coronary lesion > 50%. RESULTS: Most subjects were male (319 or 54.8%), mean age of 59.9 (± 10.6) years. A positive correlation was observed between risk scores and >coronary lesion > 50% (TIMI r = 0.363 [p 50% was: TIMI = 0.704 [CI95% 0.656-0.752; p

Elizabete Silva dos, Santos; Luciano de Figueiredo, Aguiar Filho; Daniela Menezes, Fonseca; Hugo José, Londero; Rogério Martins, Xavier; Marcos Paulo, Pereira; Luiz, Minuzzo; Roberta de, Souza; Ari, Timerman.

2013-06-01

164

Correlação dos escores de risco com a anatomia coronária na síndrome coronária aguda sem supra-ST / Correlation of risk scores with coronary anatomy in non-ST-elevation acute coronary syndrome  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese FUNDAMENTO:Há poucas publicações sobre a correlação entre escores de risco e anatomia coronária na síndrome coronária aguda (SCA). OBJETIVO: Correlacionar os escores de risco com a gravidade da lesão coronária na SCA sem supra-ST. MÉTODOS: Foram analisados 582 pacientes entre julho de 2004 e outubro [...] de 2006. Avaliou-se a correlação entre os escores de risco TIMI, GRACE hospitalar e em seis meses com lesão coronária > 50%, por método não paramétrico de Spearman. Modelo de regressão logística múltipla foi realizado para determinar a habilidade preditiva dos escores em discriminar quem terá ou não lesão coronária > 50%. RESULTADOS: Foram 319 (54,8%) homens e a média de idade era 59,9 (± 10,6) anos. Correlação positiva foi observada entre a pontuação dos escores de risco e lesão coronária > 50% (escore de risco TIMI r = 0,363 [p 50% foi: TIMI = 0,704 [IC95% 0,656-0,752; p Abstract in english BACKGROUND: The literature lacks studies regarding the correlation between risk scores and coronary anatomy in acute coronary syndrome (ACS) OBJECTIVE: Correlate risk scores with the severity of the coronary lesion in ACS with non-ST elevation. METHODS: A total of 582 patients were analyzed between [...] July 2004 and October 2006. The correlation between TIMI risk scores and GRACE (hospital and six months) scores was performed for patients with coronary lesion > 50%, using Spearman´s non-parametric method. Multiple regression logistics was used to determine the predictive ability of the scores to discriminate to discriminate who will have a coronary lesion > 50%. RESULTS: Most subjects were male (319 or 54.8%), mean age of 59.9 (± 10.6) years. A positive correlation was observed between risk scores and >coronary lesion > 50% (TIMI r = 0.363 [p 50% was: TIMI = 0.704 [CI95% 0.656-0.752; p

Elizabete Silva dos, Santos; Luciano de Figueiredo, Aguiar Filho; Daniela Menezes, Fonseca; Hugo José, Londero; Rogério Martins, Xavier; Marcos Paulo, Pereira; Luiz, Minuzzo; Roberta de, Souza; Ari, Timerman.

165

Acetabulum protrusio and center edge angle: new MR-imaging measurement criteria - a correlative study with measurement derived from conventional radiography  

Energy Technology Data Exchange (ETDEWEB)

The goal of this study was to identify a method of measurement for acetabulum protrusio and center edge angle (CEA) using MR imaging of the pelvis that correlated with classic methods using radiographic landmarks. MR images and radiographs of the pelvis in 67 patients (132 hips) were used to identify reliable MR-imaging methods for measuring protrusio acetabulum and CEA that correlated strongly with established radiographic measurements. Protrusio acetabulum was determined using the radiographic criterion that the acetabular line projects medial to the ilioischial line by 3 mm or more in men and 6 mm or more in women. Pearson correlation factor was used to determine inter-observer variability and those methods that demonstrated the strongest correlation. The mean and standard deviation of MR-imaging and radiographic measurements for both the normal and protrusio hips were established. Several MR methods correlated strongly with radiographic measurements. The preferred method employed axial MR images at the level of the ischial spine with measurement of the distance between the medial most point of the acetabular fossa and a line perpendicular to the horizontal axis that passed through the lateral margin of the posterior inner pelvic wall. The Pearson's correlation factor between radiographic and MR measurements using this method was 0.84, and inter-observer correlation was 0.80. There were 126 hips in 63 patients (17 female and 44 male) that did not meet the radiographic criteria for protrusio acetabula. In this group of normal hips, the mean and standard deviation of radiographic measurements were 1.9 and 2.8 mm in male patients and -0.5 and 1.7 mm in female patients, and the mean and standard deviation for the preferred MR method was 1.3 and 2.5 mm in male patients and -0.8 and 1.9 mm in female patients. A total of six hips in four patients (two female and two male) met the radiographic criteria for protrusio acetabula. In this group of patients, the mean and standard deviation of radiographic measurements were -3.7 and 1 mm in male patients and -5.4 and 0.9 mm in female patients, and the mean and standard deviation for the preferred MR method was -4.1 and 0.4 mm in male patients and -6.5 and 0.3 mm in female patients. Our study also showed that the CEA was best measured using anterior to middle coronal MR images. Posterior coronal MR-imaging measurements correlated poorly with radiographic measurements. MR imaging can be used to assess acetabular morphology and measure acetabulum protrusio. (orig.)

Chen, Lina; Resnick, Donald [VASDHS-Radiology, San Diego, CA (United States); UCSD Medical Center, San Diego, CA (United States); Boonthathip, Mayura; Cardoso, Fabiano; Clopton, Paul [VASDHS-Radiology, San Diego, CA (United States)

2009-02-15

166

Elective tracheostomy scoring system for severe oral disease patients  

Science.gov (United States)

Objectives The purpose of this research was to create a scoring system that provides comprehensive assessment of patients with oromaxillofacial cancer or odontogenic infection, and to statistically reevaluate the results in order to provide specific criteria for elective tracheostomy. Materials and Methods All patients that had oral cancer surgery (group A) or odontogenic infection surgery (group B) during a period of 10 years (2003 to 2013) were subgrouped according to whether or not the patient received a tracheostomy. After a random sampling (group A: total of 56, group B: total of 60), evaulation procedures were observed based on the group classifications. For group A, four factors were evaluated: TNM stage, reconstruction methods, presence of pathologic findings on chest posterior-anterior (PA), and the number of systemic diseases. Scores were given to each item based on the scoring system suggested in this research and the scores were added together. Similarly, the sum score of group B was counted using 5 categories, including infection site, C-reactive protein level on first visit, age, presence of pathologic findings on chest PA, and number of systemic diseases. Results The scoring system rendered from this research shows that there is a high correlation between the scores and TNM stage in oral cancer patients, or infection sites in odontogenic infection patients. However, no correlation between pathologic findings on chest PA could be found in either group. The results also indicated that for both groups, the hospital day increased with the tracheostomy score. The tracheostomy score cutoff value was 5 in oral cancer patients and 6 in odontogenic infection patients which was used for elective tracheostomy indication. Conclusion The elective tracheostomy score system suggested by this research is a method that considers both the surgical and general conditions of the patient, and can be very useful for managing patients with severe oral disease. PMID:25368833

Kim, Yong-Hwan; Kim, Moon-Young

2014-01-01

167

Correlação dos escores de risco com a anatomia coronária na síndrome coronária aguda sem supra-ST Correlation of risk scores with coronary anatomy in non-ST-elevation acute coronary syndrome  

Directory of Open Access Journals (Sweden)

Full Text Available FUNDAMENTO:Há poucas publicações sobre a correlação entre escores de risco e anatomia coronária na síndrome coronária aguda (SCA. OBJETIVO: Correlacionar os escores de risco com a gravidade da lesão coronária na SCA sem supra-ST. MÉTODOS: Foram analisados 582 pacientes entre julho de 2004 e outubro de 2006. Avaliou-se a correlação entre os escores de risco TIMI, GRACE hospitalar e em seis meses com lesão coronária > 50%, por método não paramétrico de Spearman. Modelo de regressão logística múltipla foi realizado para determinar a habilidade preditiva dos escores em discriminar quem terá ou não lesão coronária > 50%. RESULTADOS: Foram 319 (54,8% homens e a média de idade era 59,9 (± 10,6 anos. Correlação positiva foi observada entre a pontuação dos escores de risco e lesão coronária > 50% (escore de risco TIMI r = 0,363 [p 50% foi: TIMI = 0,704 [IC95% 0,656-0,752; p BACKGROUND: The literature lacks studies regarding the correlation between risk scores and coronary anatomy in acute coronary syndrome (ACS OBJECTIVE: Correlate risk scores with the severity of the coronary lesion in ACS with non-ST elevation. METHODS: A total of 582 patients were analyzed between July 2004 and October 2006. The correlation between TIMI risk scores and GRACE (hospital and six months scores was performed for patients with coronary lesion > 50%, using Spearman´s non-parametric method. Multiple regression logistics was used to determine the predictive ability of the scores to discriminate to discriminate who will have a coronary lesion > 50%. RESULTS: Most subjects were male (319 or 54.8%, mean age of 59.9 (± 10.6 years. A positive correlation was observed between risk scores and >coronary lesion > 50% (TIMI r = 0.363 [p 50% was: TIMI = 0.704 [CI95% 0.656-0.752; p <0.0001]; hospital GRACE = 0.623 [CI95% 0.573-0.673; p < 0.0001]; GRACE at six months= 0.562 [CI95% 0.510-0.613; p ;= 0.0255]. Comparing the areas under the ROC curve, it was found: TIMI versus hospital GRACE: p = 0.01; TIMI versus GRACE at six months:p < 0.0001; hospital GRACE versus GRACE at six months: p = 0.0461. CONCLUSION: Risk scores correlate with the severity of coronary lesions, and the TIMI risk score showed the best predictive ability.

Elizabete Silva dos Santos

2013-01-01

168

SOCIAL SCORING ?????????? ???????  

Directory of Open Access Journals (Sweden)

Full Text Available The new approach to the classification of the client by a method of credit scoring on the basis of the profiles of social networks is considered in the article. The approach illustrates interaction with social networks as new data source in credit process. Statistical methods of data processing and corresponding to them mathematical tools were involved in the analysis. The description of this approach is kept within the made experiment

Skiba S. A.

2013-09-01

169

[Prognostic criteria of systolic-diastolic correlation of medial cerebral artery of fetus in pregnant women with cytomegalovirus infection].  

Science.gov (United States)

Total of 137 women were studied with pregnancy terms between 20 and 41 weeks; out of them 97 with latent form and reactivation of cytomegalovirus infection, and 40 with non-complicated gestational process. Complex Doppler metrics study of the blood flow in the medial cerebral artery of the fetus using cluster analysis has been carried out. High percentage of complication in the II class of pregnant women has been revealed, where systolic-diastolic correlation index in medial cerebral artery of fetus was in the range of 7.1, compared to I class, where systolic-diastolic correlation index was in the interval of 3.1-7.1. Hypoxic affection of central nervous system in newborn of II class made 59.0+/-6.7% (pcytomegalovirus infection in the III trimester of gestation for revealing perinatal pathology high risk groups. PMID:17057307

Shamsadinskaia, N M; Shamsadinskaia, N M

2006-09-01

170

Keeping Score  

Science.gov (United States)

Conductor Michael Tilson Thomas has embarked on a number of intriguing and worthy projects during his career, including a series of ambitious recordings with the San Francisco Symphony and a number of well-received concerts with the late Sarah Vaughan in the 1980s. Most recently, he has teamed up with PBS (and his colleagues in the San Francisco Symphony) to create the âÂÂKeeping Score: Revolutions in Musicâ television series. Visitors to this site can explore the very fine multimedia presentations that are meant to accompany and enhance the entire educational and aesthetic experience of the television programs. Currently, there are multimedia profiles of StravinskyâÂÂs âÂÂRite of SpringâÂÂ, BeethovenâÂÂs âÂÂEroicaâ Symphony and the development of CoplandâÂÂs approach to creating an âÂÂAmericanâ sound. Each site features a brief introduction by Thomas, and then visitors are invited into the score to follow along as the piece progresses. In the top left-hand corner of the score, visitors can watch Thomas as he conducts. Overall, the experience of this website is stimulating and edifying, without being visually (or aurally) overwhelming.

171

Automated Quantitative Analysis of p53, Cyclin D1, Ki67 and pERK Expression in Breast Carcinoma Does Not Differ from Expert Pathologist Scoring and Correlates with Clinico-Pathological Characteristics  

Directory of Open Access Journals (Sweden)

Full Text Available There is critical need for improved biomarker assessment platforms which integrate traditional pathological parameters (TNM stage, grade and ER/PR/HER2 status with molecular profiling, to better define prognostic subgroups or systemic treatment response. One roadblock is the lack of semi-quantitative methods which reliably measure biomarker expression. Our study assesses reliability of automated immunohistochemistry (IHC scoring compared to manual scoring of five selected biomarkers in a tissue microarray (TMA of 63 human breast cancer cases, and correlates these markers with clinico-pathological data. TMA slides were scanned into an Ariol Imaging System, and histologic (H scores (% positive tumor area x staining intensity 0–3 were calculated using trained algorithms. H scores for all five biomarkers concurred with pathologists’ scores, based on Pearson correlation coefficients (0.80–0.90 for continuous data and Kappa statistics (0.55–0.92 for positive vs. negative stain. Using continuous data, significant association of pERK expression with absence of LVI (p = 0.005 and lymph node negativity (p = 0.002 was observed. p53 over-expression, characteristic of dysfunctional p53 in cancer, and Ki67 were associated with high grade (p = 0.032 and 0.0007, respectively. Cyclin D1 correlated inversely with ER/PR/HER2-ve (triple negative tumors (p = 0.0002. Thus automated quantitation of immunostaining concurs with pathologists’ scoring, and provides meaningful associations with clinico-pathological data.

Yolanda Madarnas

2012-07-01

172

Correlations between self-handicapping and self-defeating personality.  

Science.gov (United States)

In this study scores on Strube's self-handicapping scale were correlated with scores on Schill's self-defeating personality scale. Berglas believes there are subtypes of self-defeating personality and that his concept of self-handicapping should be correlated with the three criteria which represent a self-protective component of self-defeating personality. Some support for Berglas' proposition was found, particularly for men. However, correlations with other components of self-defeating personality suggest the criteria thought to be self-protective may need to be reconsidered. PMID:1763174

Schill, T; Morales, J; Beyler, J; Tatter, T; Swigert, L

1991-10-01

173

Change in CD3 positive T-cell expression in psoriatic arthritis synovium correlates with change in DAS28 and magnetic resonance imaging synovitis scores following initiation of biologic therapy--a single centre, open-label study.  

LENUS (Irish Health Repository)

With the development of increasing numbers of potential therapeutic agents in inflammatory disease comes the need for effective biomarkers to help screen for drug efficacy and optimal dosing regimens early in the clinical trial process. This need has been recognized by the Outcome Measures in Rheumatology Clinical Trials (OMERACT) group, which has established guidelines for biomarker validation. To seek a candidate synovial biomarker of treatment response in psoriatic arthritis (PsA), we determined whether changes in immunohistochemical markers of synovial inflammation correlate with changes in disease activity scores assessing 28 joints (?DAS28) or magnetic resonance imaging synovitis scores (?MRI) in patients with PsA treated with a biologic agent.

Pontifex, Eliza K

2011-01-01

174

Scoring with the Computer: Alternative Procedures for Improving the Reliability of Holistic Essay Scoring  

Science.gov (United States)

Automated essay scoring can produce reliable scores that are highly correlated with human scores, but is limited in its evaluation of content and other higher-order aspects of writing. The increased use of automated essay scoring in high-stakes testing underscores the need for human scoring that is focused on higher-order aspects of writing. This…

Attali, Yigal; Lewis, Will; Steier, Michael

2013-01-01

175

Correlation  

Science.gov (United States)

This chapter will discuss the concept of correlation , which is used in later chapters that will explain the concepts of validity and reliability. Here, the authors introduce the Pearson correlation coefficient, a statistic that is used with ratio

Christmann, Edwin P.; Badgett, John L.

2008-11-01

176

Genetic effect on apgar score  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Intraclass correlation coefficients for one- and five-min Apgar scores of 604 twin pairs born at a southeastern Brazilian hospital were calculated, after adjusting these scores for gestational age and sex. The data support a genetic hypothesis only for 1-min Apgar score, probably because it is less affected by the environment than 4 min later, after the newborns have been under the care of a neonatology team. First-born twins exhibited, on average, better clinical conditions than second-born ...

1999-01-01

177

2011 Y?l? Yönetici Atama ve Yer De?i?tirme Yönetme?i’nin ?çeri?ine ve Puanlama Ölçütlerine ?li?kin Yönetici Görü?lerinin ?ncelenmesi
Investigation of Manager Opinions on the Content and Scoring Criteria of the 2011 Manager Appointment and Rotation Regulations
 

Digital Repository Infrastructure Vision for European Research (DRIVER)

Purpose: This study aims at determining the opinions of managersrelating to the Manager Appointment and Rotation Regulations dated2011, the scoring criteria included in the regulations and the troublesexperienced throughout the implementation process of the regulations.Method: In this research, a qualitative approach was adopted sothat the issue can be examined thoroughly. In this research, thephenomenological pattern was employed. In the research, participantswere determined by way of sampli...

Demi?r, Selc?uk Bes?ir; Pinar, Mehmet Ali

2013-01-01

178

Acetabulum protrusio and center edge angle: new MR-imaging measurement criteria - a correlative study with measurement derived from conventional radiography  

International Nuclear Information System (INIS)

The goal of this study was to identify a method of measurement for acetabulum protrusio and center edge angle (CEA) using MR imaging of the pelvis that correlated with classic methods using radiographic landmarks. MR images and radiographs of the pelvis in 67 patients (132 hips) were used to identify reliable MR-imaging methods for measuring protrusio acetabulum and CEA that correlated strongly with established radiographic measurements. Protrusio acetabulum was determined using the radiographic criterion that the acetabular line projects medial to the ilioischial line by 3 mm or more in men and 6 mm or more in women. Pearson correlation factor was used to determine inter-observer variability and those methods that demonstrated the strongest correlation. The mean and standard deviation of MR-imaging and radiographic measurements for both the normal and protrusio hips were established. Several MR methods correlated strongly with radiographic measurements. The preferred method employed axial MR images at the level of the ischial spine with measurement of the distance between the medial most point of the acetabular fossa and a line perpendicular to the horizontal axis that passed through the lateral margin of the posterior inner pelvic wall. The Pearson's correlation factor between radiographic and MR measurements using this method was 0.84, and inter-observer correlation was 0.80. There were 126 hips in 63 patients (17 female and 44 male) that did not meet the radiograpd 44 male) that did not meet the radiographic criteria for protrusio acetabula. In this group of normal hips, the mean and standard deviation of radiographic measurements were 1.9 and 2.8 mm in male patients and -0.5 and 1.7 mm in female patients, and the mean and standard deviation for the preferred MR method was 1.3 and 2.5 mm in male patients and -0.8 and 1.9 mm in female patients. A total of six hips in four patients (two female and two male) met the radiographic criteria for protrusio acetabula. In this group of patients, the mean and standard deviation of radiographic measurements were -3.7 and 1 mm in male patients and -5.4 and 0.9 mm in female patients, and the mean and standard deviation for the preferred MR method was -4.1 and 0.4 mm in male patients and -6.5 and 0.3 mm in female patients. Our study also showed that the CEA was best measured using anterior to middle coronal MR images. Posterior coronal MR-imaging measurements correlated poorly with radiographic measurements. MR imaging can be used to assess acetabular morphology and measure acetabulum protrusio. (orig.)

179

The run-off resistance (ROR) assessed on MR angiograms may serve as a valid scoring system in patients with symptomatic peripheral arterial disease (PAD) and correlates with the ankle-brachial pressure index (ABI)  

International Nuclear Information System (INIS)

Objective: To investigate the correlation between the hemodynamic parameter ankle-brachial pressure index (ABI) and the run-off resistance (ROR) assessed on MR angiograms (MRA) in patients with peripheral arterial disease (PAD) Fontaine Stage I and II and its potential as reliable reporting system in clinical routine. Methods: Contrast-enhanced MRA was performed in 321 PAD patients using a 1.5 T MR scanner with moving bed technique. The ROR and resting ABI were determined in each patient's leg and correlation analysis was performed using the Pearson test. Results: A significant negative correlation (r = ?.513; p < .001) between ROR (mean 11.03 ± 5.42) and resting ABI (mean .81 ± .26) was identified. An even more pronounced correlation was found in patients younger than median age who had higher ABI values (r = ?.608; p < .001). Conclusion: The ROR scoring system evaluated in this series correlates better with the ABI than previously published scoring systems and could be suggested as reporting system for routine MRA evaluation.

180

Change in CD3 positive T-cell expression in psoriatic arthritis synovium correlates with change in DAS28 and magnetic resonance imaging synovitis scores following initiation of biologic therapy - a single centre, open-label study  

LENUS (Irish Health Repository)

Abstract Introduction With the development of increasing numbers of potential therapeutic agents in inflammatory disease comes the need for effective biomarkers to help screen for drug efficacy and optimal dosing regimens early in the clinical trial process. This need has been recognized by the Outcome Measures in Rheumatology Clinical Trials (OMERACT) group, which has established guidelines for biomarker validation. To seek a candidate synovial biomarker of treatment response in psoriatic arthritis (PsA), we determined whether changes in immunohistochemical markers of synovial inflammation correlate with changes in disease activity scores assessing 28 joints (?DAS28) or magnetic resonance imaging synovitis scores (?MRI) in patients with PsA treated with a biologic agent. Methods Twenty-five consecutive patients with PsA underwent arthroscopic synovial biopsies and MRI scans of an inflamed knee joint at baseline and 12 weeks after starting treatment with either anakinra (first 10 patients) or etanercept (subsequent 15 patients) in two sequential studies of identical design. DAS28 scores were measured at both time points. Immunohistochemical staining for CD3, CD68 and Factor VIII (FVIII) was performed on synovial samples and scored by digital image analysis (DIA). MRI scans performed at baseline and at 12 weeks were scored for synovitis semi-quantitatively. The ?DAS28 of the European League Against Rheumatism good response definition (>1.2) was chosen to divide patients into responder and non-responder groups. Differences between groups (Mann Whitney U test) and correlations between ?DAS28 with change in immunohistochemical and MRI synovitis scores (Spearman\\'s rho test) were calculated. Results Paired synovial samples and MRI scans were available for 21 patients (8 anakinra, 13 etanercept) and 23 patients (8 anakinra, 15 etanercept) respectively. Change in CD3 (?CD3) and CD68 expression in the synovial sublining layer (?CD68sl) was significantly greater in the disease responders compared to non-responders following treatment (P = 0.005 and 0.013 respectively). ?CD3, but not ?CD68 or ?FVIII, correlated with both ?DAS28 (r = 0.49, P = 0.025) and ?MRI (r = 0.58, P = 0.009). Conclusions The correlation of ?CD3 with ?DAS28 and ?MRI following biologic treatment in this cohort contributes to the validation of ?CD3 as a synovial biomarker of disease response in PsA, and supports the further evaluation of ?CD3 for predictive properties of future clinical outcomes.

Pontifex, Eliza K

2011-01-27

 
 
 
 
181

Pronuclear scoring as a predictor of embryo development.  

Science.gov (United States)

Many strategies have been proposed for the selection of viable embryos for transfer in human assisted reproduction. These have included morphological scoring criteria for day 1, 2, 3 and 5 embryos or combinations of these. Other strategies have used predictors such as timing of certain key events, as with early cleavage to the 2-cell, development to the 8-cell stage or patterns of fragmentation. All have shown some correlations with implantation. However, the overall success of these methods is still limited, with over 50% of all transferred embryos failing to implant. The use of pronuclear oocyte morphology has shown correlations with implantation and development to the blastocyst stage. The key aspects of pronuclear scoring, namely the presence of a cytoplasmic halo, the orientation of the nuclei in relation to the polar bodies and the size, number and pattern of distribution of nucleolar precursor bodies (NPB) in the nuclei were related to day 2,3 and 5 development, rate of development and day 3 and 5 morphology in a retrospective study. The pattern of the NPB or Z-score and the presence/absence of a halo had a significant effect on the rate of development on day 3 and day 5 and on the overall embryo morphology score. Low Z-score resulted in slow development, poor blastocyst formation and low morphology scores. The absence of a halo also resulted in slow and poor development, poor morphology, increased fragmentation and increased numbers of poor Z-scored embryos. The use of PN scoring can help predict embryos that have poor developmental potential, aid in early selection and may indicate the health of the oocyte. PMID:12676001

Scott, Lynette

2003-03-01

182

Evaluation of the Commission of the European Communities quality criteria for the paediatric lateral spine.  

Science.gov (United States)

The study aimed to evaluate the Commission of the European Communities (CEC) quality criteria for paediatric lateral spine radiographs, and to use these to assess and compare the quality of film-screen and digital images. 286 paediatric lateral spine radiographs (89 film-screen and 197 digital) were independently analysed by two observers according to the CEC criteria. Based on fulfilment of criteria, images were assigned two scores, an image criteria score and a visual grading analysis score. Sensitivity values (S) on digital radiographs were recorded and correlated with image quality. Variability for assignment of scores between observers was lower for the image criteria than the visual grading analysis technique. Analysis of variance for fulfilment of criteria between techniques, and (for digital images) age and sensitivity values was calculated. Film-screen did significantly better (p<0.05) than digital imaging for Criterion 6 (visually sharp reproduction of the cortex and trabecular markings consistent with age), but significantly worse for Criterion 7 (reproduction of the adjacent soft tissues). There was a significant difference in mean S values for each age group when Criterion 6 was or was not met. Results show that although interpretation between two observers was ambiguous, the CEC criteria were able to detect differences in quality of film-screen and digital images. It is also possible to use them when optimizing target S values. PMID:14711776

Offiah, A C; Hall, C M

2003-12-01

183

The examination of the relationship between YGS scores and music field scores in music teaching programme with special talent examination  

Directory of Open Access Journals (Sweden)

Full Text Available Every year, with special aptitude exams students are taken to undergraduate programs as a music teacher in Turkey .Although applications for these exam show differences according to the difficulty level of the questions and evaluations criterias, all the areas that would be measured show similarities to each other. The areas showing the similarity are classified as Musical hearing-reading-writing fields (M?OY , musical playing area and musical singing area. Special Ability Test score (ÖYSP Transition to Higher Education Exam scores, as well as forming the points (YGS-P and the weighted scores of Secondary Education (AOBP takes place mainly among the scores of the candidates. It is used according to the circumstances of different coefficients Placement Scores (YP in the calculation. The types of score that form YGS-P and ÖYS, which mainly affect the placemet of the students to the university, the relationship between the musical areas in ÖYSP and all correlations of the areas to each other have been seen as a basical problem of this study.761 candidates who auditioned for Music Education Program in the years 2010-2011 and 2011-2012 academic Inonu University Faculty of Education constitutes the study group . As a result of the analysis made, between the M?OY scores and YGS-P there is a meaningful relationship in positive direction and low level (r =. 08, p <. 05 In adddition, There are positive correlation and low level (r=.32, p<.01; between the musical play and M?OY area points, playing field between the musical scores of M?OY there are positive direction, the low level (r = .21, p <.05 relationship, and it has been found that there is meaningful relationship between musical play area and the Musical direction at a high level. (r=.79, p<.01

Turan Sa?er

2013-03-01

184

A Simple Clinical Score “TOPRS” to Predict Outcome in Pediatric Emergency Department in a Teaching Hospital in India  

Directory of Open Access Journals (Sweden)

Full Text Available Objective: To develop a simple clinical scoring system for severity of illness to help prioritize care and predict outcome in emergency department.Methods: Prospective hospital based observational study. Out of a total of 874 children who attended emergency department in one year, 777 were included in the study. Data was collected at the time of admission in emergency department. The baseline information like age, gender, etc and variables of ‘toprs’ score viz temperature, oxygen saturation, pulse rate, respiratory rate, sensorium and seizures were recorded. Variables were categorized as normal (score zero or abnormal (score 1 based on systemic inflammatory response syndrome (SIRS criteria and criteria mentioned in advanced pediatric life support (APLS and the total scores were computed for each child. The outcome (death/discharge was correlated with the study variables and total score. The predictive ability of score was calculated using receiver operating characteristic (ROC curve analysis.Findings: Of the six variables, temperature, oxygen saturation and respiratory rate were found to be significantly associated with mortality. Mortality increased with the increase in the number of abnormal variables. Based on the regression coefficients, maximum possible score was 6.68. The predictive ability of score was 81.7 calculated using ROC curve. Maximum discrimination was observed at a score of 2.5.Conclusion: For triage in emergency, any patient with 2 or more abnormal variables should be closely monitored and evaluated. These patients require admission as they have a potential risk of death.

Ravinder Kumar Soni

2012-03-01

185

Correlation between computer-aided dynamic gadolinium-enhanced MRI assessment of inflammation and semi-quantitative synovitis and bone marrow oedema scores of the wrist in patients with rheumatoid arthritis--a cohort study  

DEFF Research Database (Denmark)

Objective. To test the correlation between assessment of inflammation using dynamic contrast-enhanced MRI (DCE-MRI) analysed by a novel computer-aided approach and semi-quantitative scores of synovitis and bone marrow oedema (BME) using the OMERACT-RA MRI Scoring (RAMRIS) system, in the wrist of patients with RA. Methods. Fifty-four RA patients had conventional and DCE-MRI of a symptomatic wrist using a low-field 0.2T extremity scanner. RAMRIS synovitis and BME of the wrist joint were done. DCE-MRI data were analysed in three ways: (i) in all images (fully automated approach), (ii) within a large extended region of interest (ROI) placed around the wrist joint (semi-automated approach) and (iii) within a small ROI placed in the area with most visual enhancement (semi-automated approach). Time spent on each procedure was noted. Spearman's rank correlation test was applied to assess the correlation between RAMRIS and the computer-generated dynamic parameters. Results. RAMRIS synovitis (range 2-9), BME (range 0-39) and the dynamic parameters reflecting the number of enhancing voxels were significantly correlated, especially when an extended ROI around the wrist was used (??=?0.74; P?

Boesen, Mikael; Kubassova, Olga

2012-01-01

186

Prognostic value of perfusion defect volume at dual energy CTA in patients with pulmonary embolism: Correlation with CTA obstruction scores, CT parameters of right ventricular dysfunction and adverse clinical outcome  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To investigate the prognostic value of perfusion defect volume (PDvol) at dual-energy-CT-angiography (DE-CTA) in patients with acute pulmonary embolism (PE) by correlating PDvol with CTA-obstruction-scores (OS), CT parameters of right-ventricular-dysfunction (RVD), and adverse-clinical-outcome. Materials and methods: DE-CTA of 60 patients (mean age: 65 {+-} 14.4 years) with PE were analyzed. Iodine maps were generated, and normalized PDvol - defined as volume of perfusion defects/total lung volume - was quantified. Furthermore, established prognostic parameters (Qanadli and Mastora-OS, and CT parameters of RVD) were obtained. CT parameters of RVD - namely the right ventricle/left ventricle (RV/LV) diameter ratio measured on transverse sections (RV/LVtrans), four-chamber views (RV/LV4ch), and RV/LV volume ratios (RV/LVvol) - were assessed. PDvol was correlated with OS, CT parameters of RVD and adverse clinical outcome (defined as the need for intensive care treatment or death). Results: 10 of 60 patients with PE experienced adverse clinical outcome. Patients with adverse clinical outcome showed significantly higher PDvol (35 {+-} 11% vs. 23 {+-} 10%, p = 0.002), RV/LV ratios (RV/LV4ch 1.46 {+-} 0.32 vs. 1.18 {+-} 0.26, p = 0.005; RV/LVvol 2.25 {+-} 1.33 vs. 1.19 {+-} 0.56, p = 0.002) and higher Mastora global scores (52 vs. 13, p = 0.02) compared to those without adverse clinical outcome. A weak correlation was observed between PDvol and the Mastora global score (r = 0.5; p = 0.0003), as well as between PDvol and RV/LV4Ch (r = 0.432, p = 0.0006). No correlation was found between PDvol and the Qanadli score or the remainder of the RVD-CT parameters. Conclusion: The extent of perfusion defects as assessed by DE-CTA correlates with adverse clinical outcome in patients with PE. Therefore, volumetric quantification of perfusion defects at DE-CTA allows the identification of low-risk patients who do not require intensified monitoring and treatment.

Apfaltrer, Paul, E-mail: paul.apfaltrer@medma.uni-heidelberg.de [Department of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim - Heidelberg University, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim (Germany); Bachmann, Valentin, E-mail: valentin.bachmann@googl.com [Department of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim - Heidelberg University, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim (Germany); Meyer, Mathias, E-mail: mr.meyer.mathias@gmail.com [Department of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim - Heidelberg University, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim (Germany); Henzler, Thomas, E-mail: Thomas.Henzler@umm.de [Department of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim - Heidelberg University, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim (Germany); Barraza, John M., E-mail: barraza@musc.edu [Department of Radiology and Radiological Science, Medical University of South Carolina, PO Box 250322, 169 Ashley Avenue, Charleston, SC 29425 (United States); Gruettner, Joachim, E-mail: joachim.gruettner@umm.de [1st Department of Medicine, University Medical Center Mannheim, Medical Faculty Mannheim - Heidelberg University, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim (Germany); Walter, Thomas, E-mail: Thomas.Walter2@umm.de [1st Department of Medicine, University Medical Center Mannheim, Medical Faculty Mannheim - Heidelberg University, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim (Germany); Schoepf, U. Joseph, E-mail: schoepf@musc.edu [Department of Radiology and Radiological Science, Medical University of South Carolina, PO Box 250322, 169 Ashley Avenue, Charleston, SC 29425 (United States); and others

2012-11-15

187

Prognostic value of perfusion defect volume at dual energy CTA in patients with pulmonary embolism: Correlation with CTA obstruction scores, CT parameters of right ventricular dysfunction and adverse clinical outcome  

International Nuclear Information System (INIS)

Purpose: To investigate the prognostic value of perfusion defect volume (PDvol) at dual-energy-CT-angiography (DE-CTA) in patients with acute pulmonary embolism (PE) by correlating PDvol with CTA-obstruction-scores (OS), CT parameters of right-ventricular-dysfunction (RVD), and adverse-clinical-outcome. Materials and methods: DE-CTA of 60 patients (mean age: 65 ± 14.4 years) with PE were analyzed. Iodine maps were generated, and normalized PDvol – defined as volume of perfusion defects/total lung volume – was quantified. Furthermore, established prognostic parameters (Qanadli and Mastora-OS, and CT parameters of RVD) were obtained. CT parameters of RVD – namely the right ventricle/left ventricle (RV/LV) diameter ratio measured on transverse sections (RV/LVtrans), four-chamber views (RV/LV4ch), and RV/LV volume ratios (RV/LVvol) – were assessed. PDvol was correlated with OS, CT parameters of RVD and adverse clinical outcome (defined as the need for intensive care treatment or death). Results: 10 of 60 patients with PE experienced adverse clinical outcome. Patients with adverse clinical outcome showed significantly higher PDvol (35 ± 11% vs. 23 ± 10%, p = 0.002), RV/LV ratios (RV/LV4ch 1.46 ± 0.32 vs. 1.18 ± 0.26, p = 0.005; RV/LVvol 2.25 ± 1.33 vs. 1.19 ± 0.56, p = 0.002) and higher Mastora global scores (52 vs. 13, p = 0.02) compared to those without adverse clinical outcome. A weak correlation was observed between PDvol and the Mastora global score (r = 0.5; p = 0.0003), as well as between PDvol and RV/LV4Ch (r = 0.432, p = 0.0006). No correlation was found between PDvol and the Qanadli score or the remainder of the RVD-CT parameters. Conclusion: The extent of perfusion defects as assessed by DE-CTA correlates with adverse clinical outcome in patients with PE. Therefore, volumetric quantification of perfusion defects at DE-CTA allows the identification of low-risk patients who do not require intensified monitoring and treatment.

188

Maintenance and Neuronal Cell Differentiation of Neural Stem Cells C17.2 Correlated to Medium Availability Sets Design Criteria in Microfluidic Systems  

Science.gov (United States)

Background Neural stem cells (NSCs) play an important role in developing potential cell-based therapeutics for neurodegenerative disease. Microfluidics has proven a powerful tool in mechanistic studies of NSC differentiation. However, NSCs are prone to differentiate when the nutrients are limited, which occurs unfavorable by fast medium consumption in miniaturized culture environment. For mechanistic studies of NSCs in microfluidics, it is vital that neuronal cell differentiation is triggered by controlled factors only. Thus, we studied the correlation between available cell medium and spontaneous neuronal cell differentiation of C17.2 NSCs in standard culture medium, and proposed the necessary microfluidic design criteria to prevent undesirable cell phenotype changes. Methodology/Principal Findings A series of microchannels with specific geometric parameters were designed to provide different amount of medium to the cells over time. A medium factor (MF, defined as the volume of stem cell culture medium divided by total number of cells at seeding and number of hours between medium replacement) successfully correlated the amount of medium available to each cell averaged over time to neuronal cell differentiation. MF smaller than 8.3×104 µm3/cell?hour produced significant neuronal cell differentiation marked by cell morphological change and significantly more cells with positive ?-tubulin-III and MAP2 staining than the control. When MF was equal or greater than 8.3×104 µm3/cell?hour, minimal spontaneous neuronal cell differentiation happened relative to the control. MF had minimal relation with the average neurite length. Significance MFs can be controlled easily to maintain the stem cell status of C17.2 NSCs or to induce spontaneous neuronal cell differentiation in standard stem cell culture medium. This finding is useful in designing microfluidic culture platforms for controllable NSC maintenance and differentiation. This study also offers insight about consumption rate of serum molecules involved in maintaining the stemness of NSCs. PMID:25310508

Wang, Bu; Jedlicka, Sabrina; Cheng, Xuanhong

2014-01-01

189

Comparison of Human and Machine Scoring of Essays: Differences by Gender, Ethnicity, and Country  

Science.gov (United States)

Essay scores generated by machine and by human raters are generally comparable; that is, they can produce scores with similar means and standard deviations, and machine scores generally correlate as highly with human scores as scores from one human correlate with scores from another human. Although human and machine essay scores are highly related…

Bridgeman, Brent; Trapani, Catherine; Attali, Yigal

2012-01-01

190

Interpreting force concept inventory scores: Normalized gain and SAT scores  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Preinstruction SAT scores and normalized gains (G) on the force concept inventory (FCI) were examined for individual students in interactive engagement (IE) courses in introductory mechanics at one high school (N=335) and one university (N=292) , and strong, positive correlations were found for both populations ( r=0.57 and r=0.46 , respectively). These correlations are likely due to the importance of cognitive skills and abstract reasoning in learning physics. The larger correlation coeffici...

Steinert, Jeffrey J.; Coletta, Vincent P.; Phillips, Jeffrey A.

2007-01-01

191

The application of multiple-parameter scoring to antepartum fetal heart rate testing.  

Science.gov (United States)

Three hundred twenty-nine high-risk obstetric patients, undergoing 1,198 nonstressed tests (NSTs) and 101 subsequent contraction-stress tests (CSTs), were delivered during a 13-month study period. Each test was concurrently evaluated by conventional assessment criteria and by a 12-point multiple-parameter scoring system. The last test performed within one week of delivery was correlated with perinatal outcome, and the predictive accuracy of scoring was compared with conventional grading. Three NST groups were identified: group I (score: 9 to 12) had little perinatal compromise and overlapped extensively with the normally reactive group; group III (score: 0 to 4) were nearly all compromised, nonreactive by standard criteria and consistently followed by abnormal CSTs. Group II (score: 5 to 8) had an intermediate rate of compromise (33%) and was further categorized by subsequent CST outcome into normal, compromised or persistently equivocal subgroups. Scoring improved the sensitivity of CSTs, as well, when abnormal (positive or persistently equivocal). CSTs scoring below 5 were associated with a fetal compromise rate of 86%, approximately twice that of the group scoring in the 5-to-8 range. It was concluded that multiple-parameter scoring was of little benefit in improving test accuracy when the NST was normally reactive; however, scoring clearly delineated the most compromised fetal group from those requiring further evaluation when the NST was nonreactive. By combined NST-CST scoring alone, 90% of fetuses could be assigned to high- or low-risk prognostic groups with confidence; the remainder would require additional fetal data to complete their assessment. PMID:7252938

Devoe, L D; Yanowitch, G; Azor, H

1981-05-01

192

Rape Myth Acceptance, Hypermasculinity, and SAT Scores as Correlates of Moral Development: Understanding Sexually Aggressive Attitudes in First-Year College Men  

Science.gov (United States)

Male perpetrated sexual aggression has long been recognized as a serious problem on college campuses. The purpose of this multiple regression correlation study was to assess the relationship between levels of moral development (measured by the Defining Issues Test) and the degree to which first-year college men (N = 161) ascribed to rape…

Tatum, Jerry L.; Foubert, John D.

2009-01-01

193

A modification in scoring the ABC Scale.  

Science.gov (United States)

The scoring procedures for the Articulation of the Body-Concept (ABC) Scale to use with three-, four- and five-year-old children were modified to determine their degree of field-dependence-independence. A total of 300 children, who obtained a score of one or better on the ABC Scale, were administered the Preschool Embedded Figures Test (PEFT) and the ABC Scale. The ABC Scale was scored using its scoring procedures and the scoring procedures for the Goodenough-Harris Drawing Test (GHDT). Scores on the PEFT, ABC Scale and GHDT were correlated with each other. Correlations among all cognitive measures ranged from .88 to .99, which were high and statistically significant (p < .0001). Therefore, the scoring procedures for the GHDT can be substituted in scoring the ABC Scale in assessing young children's field-dependence-independence. PMID:16367481

Saracho, O N

1985-04-01

194

Correlação de três variáveis na descrição da permeabilidade nasal (HD, MCA, escala NOSE) de pacientes saudáveis / Correlation of three variables describing nasal patency (HD, MCA, NOSE score) in healthy subjects  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese Rinoresistometria e rinometria acústica são dois métodos utilizados na avaliação da função respiratória nasal. Ambos utilizam variáveis diferentes para descrever a permeabilidade nasal: o diâmetro hidráulico, HD, na rinoresistometria; e as áreas mínimas da seção transversal, MCA1 (istmo nasal) e MCA [...] 2 (cabeça do corneto inferior e corpo cavernoso do septo nasal), na rinometria acústica. OBJETIVO: Analisar a relação entre HD e MCA em pacientes sem afecções nasais e identificar se tais variáveis objetivas apresentam correlação com a escala NOSE, uma ferramenta validada para avaliar a percepção subjetiva de permeabilidade nasal. MÉTODO: Coleta estruturada dos dados de 24 indivíduos saudáveis sem afecções nasais. RESULTADOS: Correlações estatisticamente significativas de fracas a moderadas foram identificadas entre HD e MCA2 antes do descongestionamento. Foi identificada correlação moderada entre HD, MCA2 e escala NOSE no lado mais estreito. CONCLUSÃO: Na avaliação de permeabilidade nasal, parece ser recomendável determinar HD, MCA1 e MCA2, bem como uma variável subjetiva como a escala NOSE, que não aparentam ser variáveis completamente redundantes. Estudos futuros devem avaliar a correlação destas variáveis em pacientes com afecções nasais. Abstract in english Rhinoresistometry and acoustic rhinometry are two established apparative methods to objectify the respiratory function of the nose. Both methods use different variables to describe nasal patency: "hydraulic diameter", HD, in rhinoresistometry, and "minimal cross-sectional area", MCA1 (nasal isthmus) [...] and MCA2 (head of the inferior turbinate and cavernous body of the nasal septum), in acoustic rhinometry. OBJECTIVE: This study analyzes the mutual correlation of HD and MCA as a pilot study in patients without nasal pathologies. Additionally, we investigated if these objective variables correlate with the NOSE score, a validated tool to measure subjective perception of nasal patency. METHOD: Planned data collection in a collective of 24 healthy subjects without nasal pathologies. RESULTS: Statistically significant, weak to moderate correlations were found between HD and MCA2 before decongestion. A moderate correlation was found between both HD and MCA2 and the NOSE score on the narrower side. CONCLUSION: In the assessment of nasal patency, it seems advisable to determine HD, MCA1 and MCA2, but also a subjective variable such as the NOSE score, which all seem to be not fully redundant variables. In further studies, the correlation of the variables should be assessed in patients with nasal pathologies.

Thomas, Braun; Maria, Rich; Matthias F., Kramer.

2013-06-01

195

Magnetic resonance imaging versus Acute Physiology And Chronic Healthy Evaluation II score in predicting the severity of acute pancreatitis  

International Nuclear Information System (INIS)

Objective: To study the correlation between established magnetic resonance (MR) imaging criteria of disease severity in acute pancreatitis and the Acute Physiology And Chronic Healthy Evaluation II (APACHE II) score, and to assess the utility of each prognostic indicators in acute pancreatitis. Materials and methods: In this study there were 94 patients with acute pancreatitis (AP), all had abdominal MR imaging. MR findings were categorized into edematous and necrotizing AP and graded according to the MR severity index (MRSI). The APACHE II score was calculated within 24 h of admission, and local complications, death, duration of hospitalization and ICU were recorded. Statistical analysis was performed to determine their correlation. Results: In patients with pancreatitis, no significant correlation can be found between the APACHE II score and the MRSI score (P = 0.196). The MRSI score correlated well with morbidity (P = 0.006) but not with mortality (P = 0.137). The APACHE II score correlated well with mortality (P = 0.002) but not with the morbidity (P = 0.112). The MRSI score was superior to the APACHE II score as a predictor of the length of hospitalization (r = 0.52 vs. r = 0.35). A high MRSI and APACHE II score correlated with the need for being in the intensive care unit (ICU) (P = 0.000 and P = 0.000, respectively). Conclusion: In patients with pancreatitis, MRSI is superior to APACHE II in assessing local complications from pancreatitis but has a limited role in determining systemic complications in which the APACHE II score excels.

196

Checklist for Evaluating SREB-SCORE Learning Objects  

Science.gov (United States)

This checklist is based on "Evaluation Criteria for SREB-SCORE Learning Objects" and is designed to help schools and colleges determine the quality and effectiveness of learning objects. It is suggested that each learning object be rated to the extent to which it meets the criteria and the SREB-SCORE definition of a learning object. A learning…

Southern Regional Education Board (SREB), 2007

2007-01-01

197

Correlation of myocardial perfusion single photon emission computed tomography with coronary artery calcium score in coronary artery disease- An Indian perspective  

International Nuclear Information System (INIS)

Full text: Objectives: The consequences of atherosclerosis can be detected by coronary artery calcium score (CACS) and stress induced myocardial ischemia on myocardial perfusion single photon emission computed tomography (MPS). We assessed the relationship between stress induced myocardial ischemia on (MPS) and magnitude of CACS by 64 slice computed tomography (CT) in patients undergoing both tests. Methods: Our study included 59 patients with no earlier history of coronary artery disease (CAD) of both sexes (males-47, females-12) in age group of 34-69 years. Our patients were referred by cardiologists after they underwent CACS. Of these 37 patients (63%) presented with symptoms which included chest pain (non-anginal, anginal, atypical) presence or absence of shortness of breath, and rest (37%) were asymptomatic. For each patient coronary risk factors were noted. All these patients underwent CACS and rest and stress MPS one-day protocol with Tc99m sestamibi within 7 days. According to CACS and symptoms, patients were divided into four groups, group A - asymptomatic 100 n=13, group D - symptomatic >100 (n=11). The incidence of inducible ischemia in MPS was compared to the magnitude of CACS abnormality. Results: There were 21 patients (36%) with ischemic MPS. According to groups, group A - 11%(n=1), groupB- 38%(n=10), groupC- 30%(n=4) and group D- 54%(n=6) had ischemic MPS. From the above we observed that incidence of ischemic MPS is more with increasing CACS. And also it is noted that it is more frequent in patients who presented with symptoms irrespective of CACS who are at short-term risk. In negative MPS, CACS may be useful in long term risk stratification in finding out subclinical atherosclerosis. Conclusion: The general perception is that the CACS is a good tool for long-term risk stratification but it may be applicable to those patients with no significant risk factors. When there are risk factors MPS is a better indicator for risk stratification for CAD irrespective of CACS. Further studies incorporating prognostic follow- up are required. (author)

198

Three-dimensional (3D) microarchitecture correlations with 2D projection image gray-level variations assessed by trabecular bone score using high-resolution computed tomographic acquisitions: effects of resolution and noise.  

Science.gov (United States)

The aim of the present study is to determine the level of correlation between the 3-dimensional (3D) characteristics of trabecular bone microarchitecture, as evaluated using microcomputed tomography (?CT) reconstruction, and trabecular bone score (TBS), as evaluated using 2D projection images directly derived from 3D ?CT reconstruction (TBS?CT). Moreover, we have evaluated the effects of image degradation (resolution and noise) and X-ray energy of projection on these correlations. Thirty human cadaveric vertebrae were acquired on a microscanner at an isotropic resolution of 93 ?m. The 3D microarchitecture parameters were obtained using MicroView (GE Healthcare, Wauwatosa, MI). The 2D projections of these 3D models were generated using the Beer-Lambert law at different X-ray energies. Degradation of image resolution was simulated (from 93 to 1488 ?m). Relationships between 3D microarchitecture parameters and TBS?CT at different resolutions were evaluated using linear regression analysis. Significant correlations were observed between TBS?CT and 3D microarchitecture parameters, regardless of the resolution. Correlations were detected that were strongly to intermediately positive for connectivity density (0.711 ? r² ? 0.752) and trabecular number (0.584 ? r² ? 0.648) and negative for trabecular space (-0.407 ? r² ? -0.491), up to a pixel size of 1023 ?m. In addition, TBS?CT values were strongly correlated between each other (0.77 ? r² ? 0.96). Study results show that the correlations between TBS?CT at 93 ?m and 3D microarchitecture parameters are weakly impacted by the degradation of image resolution and the presence of noise. PMID:22749406

Winzenrieth, Renaud; Michelet, Franck; Hans, Didier

2013-01-01

199

Decompositions of Proper Scores  

CERN Document Server

Scoring rules are an important tool for evaluating the performance of probabilistic forecasts. A popular example is the Brier score, which allows for a decomposition into terms related to the sharpness (or information content) and to the reliability of the forecast. This feature renders the Brier score a very intuitive measure of forecast quality. In this paper, it is demonstrated that all strictly proper scoring rules allow for a similar decomposition into reliability and sharpness related terms. This finding underpins the importance of proper scores and yields further credence to the practice of measuring forecast quality by proper scores. Furthermore, the effect of averaging multiple probabilistic forecasts on the score is discussed. It is well known that the Brier score of a mixture of several forecasts is never worse that the average score of the individual forecasts. This property hinges on the convexity of the Brier score, a property not universal among proper scores. Arguably, this phenomenon portends...

Bröcker, Jochen

2008-01-01

200

Assessment of lung disease in children with cystic fibrosis using hyperpolarized 3-Helium MRI: comparison with Shwachman score, Chrispin-Norman score and spirometry  

Energy Technology Data Exchange (ETDEWEB)

This study assesses the feasibility of hyperpolarized 3-Helium MRI in children with cystic fibrosis (CF) and correlates the findings with standard clinical parameters based on chest radiograph (CXR) and pulmonary function tests (PFT). An uncontrolled, observational study in eighteen children with cystic fibrosis aged 5 - 17 years (median 12.1 years), with different severity of disease was carried out. All subjects underwent routine clinical assessment including PFT and standard auxology; CXR was obtained and Shwachman and Chrispin-Norman scores calculated. Hyperpolarized 3-He magnetic resonance imaging (MRI) was carried out using a spin-exchange polarizer and a whole body 1.5 T scanner. Ventilation distribution images were obtained during a 21-second breath-hold and scored according to previously defined criteria. Spearman's non-parametric correlations test was performed to assess for statistical significance at the p<0.05 level. The children tolerated the procedure well. No desaturation events were observed during 3-He MRI. A significant, albeit moderate, correlation was found between MRI score and FEV1% predicted (r=-0.41; p=0.047) and FVC% predicted (r=-0.42; p=0.04), while there were trends of correlations between Shwachman score and MRI score (r=-0.38; p=0.06) and Shwachman score and FEV1% predicted (r=0.39; p=0.055). The feasibility of hyperpolarized 3-He MRI in children with CF was demonstrated. MRI appears to be able to demonstrate functional lung changes, although correlations with routine clinical tests are only moderate to poor. This non-ionising radiation technique could be useful for monitoring lung disease and assessing therapy in this patient population. (orig.)

Beek, Edwin J.R. van [University of Sheffield, Unit of Academic Radiology, Sheffield (United Kingdom); University of Iowa, Department of Radiology, Carver College of Medicine, Iowa City (United States); University of Iowa, Department of Radiology, Iowa City, IA (United States); Hill, Catherine; Woodhouse, Neil; Fichele, Stanislao; Fleming, Sally; Wild, Jim M. [University of Sheffield, Unit of Academic Radiology, Sheffield (United Kingdom); Howe, Bridget; Bott, Sandra; Taylor, Christopher J. [University of Sheffield, Academic Unit of Child Health, Sheffield (United Kingdom)

2007-04-15

 
 
 
 
201

Assessment of lung disease in children with cystic fibrosis using hyperpolarized 3-Helium MRI: comparison with Shwachman score, Chrispin-Norman score and spirometry  

International Nuclear Information System (INIS)

This study assesses the feasibility of hyperpolarized 3-Helium MRI in children with cystic fibrosis (CF) and correlates the findings with standard clinical parameters based on chest radiograph (CXR) and pulmonary function tests (PFT). An uncontrolled, observational study in eighteen children with cystic fibrosis aged 5 - 17 years (median 12.1 years), with different severity of disease was carried out. All subjects underwent routine clinical assessment including PFT and standard auxology; CXR was obtained and Shwachman and Chrispin-Norman scores calculated. Hyperpolarized 3-He magnetic resonance imaging (MRI) was carried out using a spin-exchange polarizer and a whole body 1.5 T scanner. Ventilation distribution images were obtained during a 21-second breath-hold and scored according to previously defined criteria. Spearman's non-parametric correlations test was performed to assess for statistical significance at the p<0.05 level. The children tolerated the procedure well. No desaturation events were observed during 3-He MRI. A significant, albeit moderate, correlation was found between MRI score and FEV1% predicted (r=-0.41; p=0.047) and FVC% predicted (r=-0.42; p=0.04), while there were trends of correlations between Shwachman score and MRI score (r=-0.38; p=0.06) and Shwachman score and FEV1% predicted (r=0.39; p=0.055). The feasibility of hyperpolarized 3-He MRI in children with CF was demonstrated. MRI appears to be able to demonstrate functional lung changes, alto demonstrate functional lung changes, although correlations with routine clinical tests are only moderate to poor. This non-ionising radiation technique could be useful for monitoring lung disease and assessing therapy in this patient population. (orig.)

202

Using Minimum Acceptable GRE Scores for Graduate Admissions Suppresses Diversity  

Science.gov (United States)

I will present data showing that significant performance disparities on the GRE general test exist based on the test taker's race and gender [1]. Because of the belief that high GRE scores qualify one for graduate studies, the diversity issues faced by STEM fields may originate, at least in part, in misuse of the GRE scores by graduate admissions committees. I will quantitatively demonstrate this by showing that the combination of a hard cut-off and the different score distributions leads to the systematic underrepresentation of certain groups. I will present data from USF’s PhD program that shows a lack of correlation between GRE scores and research ability; similar null results are emerging from numerous other programs. I will then discuss how assessing non-cognitive competencies in the selection process may lead to a more enlightened search for the next generation of scientists. [1] C. W. Miller, "Admissions Criteria and Diversity in Graduate School", APS News Vol 22, Issue 2, The Back Page (2013) http://www.aps.org/publications/apsnews/201302/backpage.cfm

Miller, Casey

2014-01-01

203

Genetic effect on apgar score  

Directory of Open Access Journals (Sweden)

Full Text Available Intraclass correlation coefficients for one- and five-min Apgar scores of 604 twin pairs born at a southeastern Brazilian hospital were calculated, after adjusting these scores for gestational age and sex. The data support a genetic hypothesis only for 1-min Apgar score, probably because it is less affected by the environment than 4 min later, after the newborns have been under the care of a neonatology team. First-born twins exhibited, on average, better clinical conditions than second-born twins. The former showed a significantly lower proportion of Apgar scores under seven than second-born twins, both at 1 min (17.5% vs. 29.8% and at 5 min (7.2% vs. 11.9%. The proportion of children born with "good" Apgar scores was significantly smaller among twins than among 1,522 singletons born at the same hospital. Among the latter, 1- and 5-min Apgar scores under seven were exhibited by 9.2% and 3.4% newborns, respectively.

Franchi-Pinto Carla

1999-01-01

204

Scoring systems in high risk pregnancy.  

Science.gov (United States)

Antenatal care serves the purpose of screening malformations and detecting treatable medical conditions as well as identifying high risk pregnancies (HRP). HRP scoring systems require reliable statistics, well-defined objectives, the definition of high risk conditions, and the recognition of the capabilities of these systems. Primary care doctors can take advantage of the modified Al-Zahraa University (Z.U.H.) high risk score for prenatal risk assessing cardiovascular, renal, and metabolic history as well as anatomic abnormalities; the modified Bishop scoring system for assessment of the state of the uterine cervix (1964); the Zatuchni-Andros criteria for scoring of breech delivery (1967); the fetal heart rate tracing score as modified later Kaar to predict feto-placental functions (1980); and the biophysical profile scoring technique. Secondary and tertiary care doctors are recommended to use scores relating to maternal factors, placental factors, and fetal factors in addition to the modified Z.U.H. high risk score. The Apgar score is used for the assessment of the newborn after delivery. These scoring systems are not perfect, as false positives and false negatives do occur that could be minimized by finer screening using clinical tests. PMID:12317329

Fatouh, A A; Fakhr, M M

1991-01-01

205

CT densitovolumetry in children with obliterative bronchiolitis: correlation with clinical scores and pulmonary function test results / Densitovolumetria pulmonar por TC em criancas com bronquiolite obliterante: correlacao com escores clinicos e testes de funcao pulmonar  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in portuguese OBJETIVO: Determinar as correlações entre o volume de aprisionamento aéreo em relação ao volume pulmonar total (AA%) e parâmetros clínicos e funcionais em crianças com bronquiolite obliterante (BO). MÉTODOS: Técnicas de pós-processamento de imagem foram usadas em imagens de TC de 19 crianças c [...] om BO para quantificar AA% por meio de um limiar fixo de ?950 UH (AA%950) e de limiares selecionados por meio de máscaras de densidade (AA%MD). Os pacientes foram divididos em três grupos, de acordo com a gravidade de AA%. Foram examinadas as correlações entre AA% e a saturação de oxigênio (SO2) em repouso, a distância percorrida no teste de caminhada de seis minutos (DTC6), a SO2 mínima durante o teste de caminhada de seis minutos (SO2_TC6), a CVF, o VEF1, a relação VEF1/CVF e parâmetros clínicos. RESULTADOS: A DTC6 foi maior nos pacientes com maiores volumes pulmonares normais (r = 0,53). Na amostra como um todo, encontramos (antes e depois da exclusão de valores extremos, respectivamente), correlações estatisticamente significativas entre AA%950 e o escore clínico (r = 0,72; 0,80), a CVF (r = 0,24; 0,59), o VEF1 (r = ?0,58; ?0,67) e a relação VEF1/CVF (r = ?0,53; r = ?0,62), bem como entre AA%MD e o escore clínico (r = 0,58; r = 0,63), a SO2 em repouso (r = ?0,40; r = ?0,61), a SO2_TC6 (r = ?0,24; r = ?0,55), a CVF (r = ?0,44; r = ?0,80), o VEF1 (r = ?0,65; r = ?0,71) e a relação VEF1/CVF (r = ?0,41; r = ?0,52). CONCLUSÕES: Os resultados deste estudo mostram que AA% correlaciona-se significativamente com escores clínicos e testes de função pulmonar em crianças com BO. Abstract in english OBJECTIVE: To determine whether air trapping (expressed as the percentage of air trapping relative to total lung volume [AT%]) correlates with clinical and functional parameters in children with obliterative bronchiolitis (OB). METHODS: CT scans of 19 children with OB were post-processed for A [...] T% quantification with the use of a fixed threshold of ?950 HU (AT%950) and of thresholds selected with the aid of density masks (AT%DM). Patients were divided into three groups by AT% severity. We examined AT% correlations with oxygen saturation (SO2) at rest, six-minute walk distance (6MWD), minimum SO2 during the six-minute walk test (6MWT_SO2), FVC, FEV1, FEV1/FVC, and clinical parameters. RESULTS: The 6MWD was longer in the patients with larger normal lung volumes (r = 0.53). We found that AT%950 showed significant correlations (before and after the exclusion of outliers, respectively) with the clinical score (r = 0.72; 0.80), FVC (r = 0.24; 0.59), FEV1 (r = ?0.58; ?0.67), and FEV1/FVC (r = ?0.53; r = ?0.62), as did AT%DM with the clinical score (r = 0.58; r = 0.63), SO2 at rest (r = ?0.40; r = ?0.61), 6MWT_SO2 (r = ?0.24; r = ?0.55), FVC (r = ?0.44; r = ?0.80), FEV1 (r = ?0.65; r = ?0.71), and FEV1/FVC (r = ?0.41; r = ?0.52). CONCLUSIONS: Our results show that AT% correlates significantly with clinical scores and pulmonary function test results in children with OB.

Helena, Mocelin; Gilberto, Bueno; Klaus, Irion; Edson, Marchiori; Edgar, Sarria; Guilherme, Watte; Bruno, Hochhegger.

206

CT densitovolumetry in children with obliterative bronchiolitis: correlation with clinical scores and pulmonary function test results / Densitovolumetria pulmonar por TC em criancas com bronquiolite obliterante: correlacao com escores clinicos e testes de funcao pulmonar  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in portuguese OBJETIVO: Determinar as correlações entre o volume de aprisionamento aéreo em relação ao volume pulmonar total (AA%) e parâmetros clínicos e funcionais em crianças com bronquiolite obliterante (BO). MÉTODOS: Técnicas de pós-processamento de imagem foram usadas em imagens de TC de 19 crianças c [...] om BO para quantificar AA% por meio de um limiar fixo de ?950 UH (AA%950) e de limiares selecionados por meio de máscaras de densidade (AA%MD). Os pacientes foram divididos em três grupos, de acordo com a gravidade de AA%. Foram examinadas as correlações entre AA% e a saturação de oxigênio (SO2) em repouso, a distância percorrida no teste de caminhada de seis minutos (DTC6), a SO2 mínima durante o teste de caminhada de seis minutos (SO2_TC6), a CVF, o VEF1, a relação VEF1/CVF e parâmetros clínicos. RESULTADOS: A DTC6 foi maior nos pacientes com maiores volumes pulmonares normais (r = 0,53). Na amostra como um todo, encontramos (antes e depois da exclusão de valores extremos, respectivamente), correlações estatisticamente significativas entre AA%950 e o escore clínico (r = 0,72; 0,80), a CVF (r = 0,24; 0,59), o VEF1 (r = ?0,58; ?0,67) e a relação VEF1/CVF (r = ?0,53; r = ?0,62), bem como entre AA%MD e o escore clínico (r = 0,58; r = 0,63), a SO2 em repouso (r = ?0,40; r = ?0,61), a SO2_TC6 (r = ?0,24; r = ?0,55), a CVF (r = ?0,44; r = ?0,80), o VEF1 (r = ?0,65; r = ?0,71) e a relação VEF1/CVF (r = ?0,41; r = ?0,52). CONCLUSÕES: Os resultados deste estudo mostram que AA% correlaciona-se significativamente com escores clínicos e testes de função pulmonar em crianças com BO. Abstract in english OBJECTIVE: To determine whether air trapping (expressed as the percentage of air trapping relative to total lung volume [AT%]) correlates with clinical and functional parameters in children with obliterative bronchiolitis (OB). METHODS: CT scans of 19 children with OB were post-processed for A [...] T% quantification with the use of a fixed threshold of ?950 HU (AT%950) and of thresholds selected with the aid of density masks (AT%DM). Patients were divided into three groups by AT% severity. We examined AT% correlations with oxygen saturation (SO2) at rest, six-minute walk distance (6MWD), minimum SO2 during the six-minute walk test (6MWT_SO2), FVC, FEV1, FEV1/FVC, and clinical parameters. RESULTS: The 6MWD was longer in the patients with larger normal lung volumes (r = 0.53). We found that AT%950 showed significant correlations (before and after the exclusion of outliers, respectively) with the clinical score (r = 0.72; 0.80), FVC (r = 0.24; 0.59), FEV1 (r = ?0.58; ?0.67), and FEV1/FVC (r = ?0.53; r = ?0.62), as did AT%DM with the clinical score (r = 0.58; r = 0.63), SO2 at rest (r = ?0.40; r = ?0.61), 6MWT_SO2 (r = ?0.24; r = ?0.55), FVC (r = ?0.44; r = ?0.80), FEV1 (r = ?0.65; r = ?0.71), and FEV1/FVC (r = ?0.41; r = ?0.52). CONCLUSIONS: Our results show that AT% correlates significantly with clinical scores and pulmonary function test results in children with OB.

Helena, Mocelin; Gilberto, Bueno; Klaus, Irion; Edson, Marchiori; Edgar, Sarria; Guilherme, Watte; Bruno, Hochhegger.

2013-12-01

207

7 CFR 3406.15 - Evaluation criteria for teaching proposals.  

Science.gov (United States)

...2010-01-01 false Evaluation criteria for teaching proposals. 3406.15 Section 3406...GRANTS PROGRAM Review and Evaluation of a Teaching Proposal § 3406.15 Evaluation criteria for teaching proposals. The maximum score a...

2010-01-01

208

2011 Y?l? Yönetici Atama ve Yer De?i?tirme Yönetme?i’nin ?çeri?ine ve Puanlama Ölçütlerine ?li?kin Yönetici Görü?lerinin ?ncelenmesi Investigation of Manager Opinions on the Content and Scoring Criteria of the 2011 Manager Appointment and Rotation Regulations  

Directory of Open Access Journals (Sweden)

Full Text Available Purpose: This study aims at determining the opinions of managersrelating to the Manager Appointment and Rotation Regulations dated2011, the scoring criteria included in the regulations and the troublesexperienced throughout the implementation process of the regulations.Method: In this research, a qualitative approach was adopted sothat the issue can be examined thoroughly. In this research, thephenomenological pattern was employed. In the research, participantswere determined by way of sampling for maximum diversity-one of theintentional sampling methods. The study group of the research consistsof 8 managers holding Office in the city X (pseudonym. Terms of Officeof the participants varies between 25 and 8 years. Semi-structuredinterview form was used as data collection tools in the research. All theinterviews were recorded on a tape recorder throughout the research. A240-minute interview was had within the scope of the research; the taperecording was computerized through the Microsoft Word processingprogram as raw data without being subjected to any screening.Line by line analysis described by Patton, (2002 was employed todescribe opinions expressed clearly and directly or implied in anindirect manner by the participants on the aim of the study withoutmanipulating them. Inductive descriptive analysis, content analysis andthe constant comparison technique was used in the interpretation ofthe interview data. The descriptive analysis project is made up of fourmain stages, namely, building up the thematic framework, processingdata according to the thematic framework, identifying the findings andinterpreting the findings.During content analysis, on the other hand, the data was dividedinto parts first and then these parts were investigated and compared.Later, meaningful concepts were built from these parts and the codesevoking the same concepts were grouped under a joint category. In thefinal stage, content integrity was derived from the themes stemmingfrom the data and interpreted.While developing an interview form, a conceptual frameworkrelating to the subject matter was formed by investigating the relatedbody of literature for the purposes of increasing credibility/ internalvalidity of the research. Each stage of the research process wasprovided to the reader in a detailed manner so that thetransferability/external validity of the research could be insured. Theresearcher has watched over to write his research report in detail andtried to present detailed descriptions in the findings part.All the data obtained throughout the research process wasevaluated and separately coded by the researcher and an instructor,who has a command of qualitative research methods and a consensuswas reached on the codings in general terms. Results: As a result of analysis of the data, three main subjects, namely, 1. Evaluations relating to the appointment and change of Office of managers, 2. Evaluations relating to the content of the Manager Appointment and Change of Office Regulations and to the scoring principles, 3. Evaluations relating to compulsory rotation appeared.As a result of the story, it was concluded that the belief that the awards (certificates of appreciation and high achievement granted by the Ministry of National Education central organization and provincial organizations and by the related civilian authority are not offered based on merits, justice and qualification and in line with objective criteria dominated the participants and based on this idea, they had the idea that scoring of these awards in the manager appointment process may lead to unfair competition and injustice.It was found out in the study that the participants objected not to the scoring of the awards in the appointment of manager; just to the contrary, they argued against the scoring of these awards in the manager appointment process based on the idea that the awards granted were not given according to objective criteria.It was observed that the participants believing that there is a relationship between the term of Office and experience an

Selçuk Be?ir DEM?R

2013-07-01

209

Fratura na coluna vertebral por mieloma múltiplo: correlação entre sobrevida e índices de Tomita e Tokuhashi / Multiple myeloma and vertebral fractures: correlation between survival rate and Tomita and Tokuhashi scores / Fractura de la columna vertebral por mieloma múltiple: correlación entre sobrevida e índices de Tomita y Tokuhashi  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese OBJETIVO: o mieloma múltiplo (MM) é a neoplasia óssea primária mais freqüente na coluna vertebral. Em razão da grande morbi-mortalidade destas lesões, discute-se qual o melhor tratamento nestes pacientes. Na prática, observamos similaridade das opções de tratamento entre os pacientes portadores de m [...] etástases ósseas e MM. Os índices de sobrevida de Tomita e Tokuhashi são utilizados com o intuito de auxiliar na escolha do tratamento nos portadores de metástases. Faltam estudos sobre a aplicabilidade destes índices em pacientes portadores de MM. Neste trabalho vamos avaliar a aplicabilidade dos índices de Tomita e Tokuhashi nos pacientes portadores de MM e lesão vertebral. MÉTODOS: estudo retrospectivo mediante avaliação de prontuários e radiografias de portadores de MM por meio da aplicação dos critérios de Tomita e Tokuhashi. RESULTADOS: em um ano, 19 (63,3%) estavam vivos, em dois anos 13 (43,3%) e em cinco anos quatro (13,3%) pacientes estavam vivos. Não houve correlação entre os índices (Tomita e Tokuhashi) e a taxa de sobrevida nestes pacientes (p= 0,2255). CONCLUSÃO: há necessidade de adaptação dos índices de Tomita e Tokuhashi para apresentarem aplicabilidade nos portadores de MM na coluna. Abstract in spanish OBJETIVO: el Mieloma Múltiple (MM) es la neoplasia ósea primaria más frecuente en la columna vertebral. En razón de la gran morbimortalidad de estas lesiones, se discute cuál sería el mejor tratamiento en estos pacientes. En la práctica observamos semejanza de las opciones de tratamiento entre los p [...] acientes portadores de metástasis óseas y MM. Los índices de sobrevida de Tomita y Tokuhashi son utilizados con el objetivo de auxiliar en la opción del tratamiento en los portadores de metástasis. Faltan estudios sobre la aplicabilidad de estos índices en pacientes portadores de MM. En este trabajo vamos a evaluar la aplicabilidad de los índices de Tomita y Tokuhashi en los pacientes portadores de MM y lesión vertebral. MÉTODOS: estudio retrospectivo mediante evaluación de historias clínicas y radiografías de portadores de MM por medio de la aplicación de los criterios de Tomita y Tokuhashi. RESULTADOS: En un año 19 estuvieron vivos (63.3%), en 2 años fueron 13 (43.3%) y en 5 años fueron 4 los que estuvieron vivos (13.3%). No hubo correlación entre los índices (Tomita y Tokuhashi) y la tasa de sobrevida en estos pacientes (p= 0.2255). CONCLUSIÓN: Hay necesidad de adaptación de los índices de Tomita y Tokuhashi para presentar una aplicabilidad en los portadores de MM en la columna. Abstract in english OBJECTIVE: multiple myeloma (MM) is the most common primary neoplasm tumor in the spine. Due to the high morbidity and mortality of these spinal lesions, it is of important to discuss the best treatment in these patients. In clinical practice, there are similarities in the treatment options for pati [...] ents with bone metastasis and MM. The survival rates of Tomita and Tokuhashi scores are used in order to assist in the choice of treatment patients with metastasis. No studies about the applicability of these scores in patients with MM were found. The objective of this study is to evaluate the applicability of Tomita and Tokuhashi scores in patients with MM and vertebral lesions. METHODS: Retrospective study on evaluation of radiographs and medical records of patients with MM using the criteria of Tomita and Tokuhashi. RESULTS: At 1 year 19 (63.3%) were alive, 2 years 13 (43.3%) and 5 years 4 (13.3%) patients were alive. There was no correlation between the scores (Tomita and Tokuhashi) and survival rate in these patients (p = 0.2255). CONCLUSION: There is a need for adjustment or alterations of the scores of Tomita and Tokuhashi to have applicability in patients with MM in column.

Osmar, Avanzi; Elcio, Landim; Robert, Meves; Maria Fernanda Silber, Caffaro; Marcos Vaz de, Lima.

210

Developmental Sentence Scoring for Japanese (DSSJ)  

Science.gov (United States)

This paper reports on the development and use of the Developmental Sentence Scoring for Japanese (DSSJ), a new morpho-syntactical measure for Japanese constructed after the model of the English Developmental Sentence Scoring model (Lee, 1974). Using this measure, we calculated DSSJ scores for 84 children divided into six age groups between 2;8 and 5;2 on the basis of 100-sentence samples collected from free-play child-adult conversations. The analysis showed a high correlation of the DSSJ overall score with the Mean Length of Utterance. The analysis of the DSSJ subarea scores revealed large variations between these subarea scores for children with similar overall DSSJ scores. When investigating the high-scoring children (over 1 SD over group average), most children scored high in three to five subareas, but the combination of scores for these subareas varied from child to child. It is concluded that DSSJ is a valuable tool especially for the language acquisition research. The overall DSSJ score reliably reflects the overall morpho-syntactic development of Japanese children, and the subarea scores provide specific information on individual acquisition patterns.

Miyata, Susanne; MacWhinney, Brian; Otomo, Kiyoshi; Sirai, Hidetosi; Oshima-Takane, Yuriko; Hirakawa, Makiko; Shirai, Yasuhiro; Sugiura, Masatoshi; Itoh, Keiko

2014-01-01

211

Correlações genéticas de características de tamanho corporal e condição corporal com características de eficiência produtiva de fêmeas da raça Canchim / Genetic correlations among cow body size, condition score and productive traits in Canchim cows  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese Os objetivos neste trabalho foram estimar a herdabilidade do número (NBZ10 e NBZT) e quilogramas de bezerros desmamados (QBD10 e QBDT) pela vaca até dez anos de idade e durante a permanência da fêmea no rebanho e de quilogramas de bezerros desmamados pela vaca por ano de permanência no rebanho (QTPR [...] ) e as correlações genéticas dessas características com os pesos ajustados e não-ajustados para condição corporal, índice de tamanho corporal e condições corporais à primeira monta, ao primeiro parto e à idade adulta, idades ao primeiro, segundo e terceiro partos e tempo de permanência no rebanho. Os componentes de variância e de co-variância foram estimados pelo método da máxima verossimilhança restrita livre de derivadas, usando-se análises uni e bicaracterísticas. Os modelos estatísticos incluíram o efeito genético aditivo direto, como aleatório, e o efeito fixo de grupo de contemporâneos. As estimativas de herdabilidade obtidas das análises unicaracterísticas foram 0,10 ± 0,05 (NBZT), 0,10 ± 0,03 (QBDT), 0,12 ± 0,05 (NBZ10), 0,13 ± 0,05 (QBD10) e 0,15 ± 0,05 (QTPR), indicando que baixa resposta à seleção será obtida para essas características. A seleção para redução na idade ao primeiro parto não incrementará a produtividade das vacas. A seleção para aumentar o peso adulto das fêmeas acarretará redução em QTPR, NBZ10 e NBZT. A seleção para os índices de tamanho corporal ou para os pesos ajustados para condição corporal deve apresentar respostas correlacionadas com as características produtivas das fêmeas com tendências semelhantes, mas de maior magnitude que a seleção para peso da fêmea sem ajuste. Abstract in english The objectives of this study were to obtain heritability estimates for number (NBZ10 and NBZT) and kilograms (QBD10 and QBDT) of calves weaned up to ten years of age and during herd life, kilograms of calves weaned per year in herd (QTPR) and their genetic correlations with culling age, ages at firs [...] t, at second and at third calving, adjusted and unadjusted weights for condition score, body size indexes and condition score at first mating, at first calving and at mature age. Variance and covariance components were estimated by REML using univariate and bivariate models including the fixed effect of contemporary group and additive direct genetic and residual as random effects. Heritability estimates obtained from univariate analyses were 0.10 ± 0.05 (NBZT), 0.10 ± 0.03 (QBDT), 0.12 ± 0.05 (NBZ10), 0.13 ± 0.05 (QBD10) and 0.15 ± 0.05 (QTPR) and indicate low response by selection on these traits. Genetic correlation estimate suggest that selection for reducing age at first calving will not improve cow productivity. Selection for increasing mature weight will reduce kilograms of calves weaned per year in herd and the number of calves weaned up to ten years of age and during herd life. Selection on body size indexes and on cow weights adjusted for condition score may result in similar correlated responses in productive traits of cows, which would be higher than those from selection on unadjusted cow weights.

Fernando, Baldi; Mauricio Mello de, Alencar; Alfredo Ribeiro de, Freitas.

2008-03-01

212

The relationship between interview-based schizotypal personality dimension scores and the continuous performance test.  

Science.gov (United States)

The existing research that has examined cognitive performance in samples with subclinical schizotypal personality features has been largely limited to psychometric self-report questionnaires, which may be biased by distorted self-awareness of symptoms. The present study examined the relationship between performance on a degraded-AX continuous performance test (CPT) and continuous dimension scores created from a structured clinical interview for schizotypal personality disorder (SPD), which reflected both the breadth and severity of schizotypal personality symptoms, in 52 undergraduate students. Only one participant met full diagnostic criteria for SPD. The overall dimension score from the SPD clinical interview showed a positive correlation with both omission (r(s)=.47) and false alarm (r(s)=.41) errors on the CPT. Interpersonal symptoms were positively correlated with omission errors (r(s)=.47), while Disorganized symptoms were positively correlated with false alarm errors (r(s)=.40). Results suggest that higher SPD interview-based dimension scores are associated with lower levels of performance on the CPT, even when examining a relatively subclinical sample of young adults. In contrast, scores from the psychometric Abbreviated Schizotypal Personality Questionnaire in the same sample did not correlate with accuracy measures on the CPT, suggesting that the interview-based measure of schizotypal personality may have a stronger relationship with CPT accuracy. Findings also add to a growing literature suggesting that Interpersonal SPD symptoms are primarily related to omission errors, while Disorganized SPD symptoms are primarily related to false alarm errors. PMID:19101122

Bedwell, Jeffrey S; Kamath, Vidyulata; Compton, Michael T

2009-03-01

213

Algorithmic scoring models  

Directory of Open Access Journals (Sweden)

Full Text Available This article is devoted to the analysis of different credit scoring modeling techniques which can be used for the large datasets processing. Credit scoring is a basis of the banking system. There are lots if information gathered in the banks’ databases which should be used in the scoring. This article describes the basic methods and technologies of scoring models development for the risk management of the banking system.

K. Nurlybayeva

2013-01-01

214

A comparative study of conservation and variation scores  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Conservation and variation scores are used when evaluating sites in a multiple sequence alignment, in order to identify residues critical for structure or function. A variety of scores are available today but it is not clear how different scores relate to each other. Results We applied 25 conservation and variation scores to alignments from the Catalytic Site Atlas (CSA. We calculated distances among scores based on correlation coefficients, and constructed a dendrogram of the scores by average linking cluster analysis. The cluster analysis showed that most scores fall into one of two groups--substitution matrix based group and frequency based group respectively. We also evaluated the scores' performance in predicting catalytic sites and found that frequency based scores generally perform best. Conclusions Conservation and variation scores can be classified into mainly two large groups. When using a score to predict catalytic sites, frequency based scores that also consider a background distribution are most successful.

Toh Hiroyuki

2010-07-01

215

Relationship of age, American College Testing scores, grade point average, and State Board Examination scores.  

Science.gov (United States)

The relationships between age and American College Testing (ACT) scores to college grade point average (GPA), and State Board scores were studied. The sample consisted of 787 persons admitted by two different procedures to an associate degree nursing program over a 10-year period. An age bias was found with significant negative correlations for each ACT score and age. The proportion of older students who graduated and passed the State Board examinations was significantly higher than the proportion of younger students. The two admission procedures resulted in similar rates for graduation and State Board passage. Age and ACT scores were not correlated with the GPA. Age and ACT scores, with the exception of mathematics, were positively correlated with the State Board scores. PMID:6553945

Aldag, J; Rose, S

1983-06-01

216

What Is the Apgar Score?  

Science.gov (United States)

... Media: Connect With Us What Is the Apgar Score? KidsHealth > Parents > Pregnancy & Newborn Center > Q&As > What ... Score What Apgar Scores Mean About the Apgar Score The Apgar score, the very first test given ...

217

Herdabilidade e correlações quanto a peso, perímetro escrotal e escores visuais à desmama, em bovinos Canchim / Heritability and correlations for weight, scrotal circumference and visual scores at weaning, in Canchim beef cattle  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese O objetivo deste trabalho foi estabelecer o modelo mais adequado para avaliação genética de bovinos Canchim e estimar os parâmetros genéticos de características produtivas à desmama. Foram utilizados dados de: 12.103 animais, quanto ao peso (PD); 5.278, quanto ao perímetro escrotal (PE); 8.343, quan [...] to ao escore visual da conformação frigorífica (CF); 9.111, quanto ao escore de umbigo (UM); e 7.986, quanto ao escore de pelame (PEL). Os modelos estatísticos incluíram os efeitos fixos e os efeitos aleatórios genéticos aditivos direto, materno e de ambiente permanente materno, em diferentes combinações. As análises foram feitas pelo método da máxima verossimilhança restrita livre de derivadas. O modelo completo foi o mais adequado para PD, PE, CF e UM, enquanto o modelo com uso apenas dos efeitos genéticos aditivos direto e materno foi o mais adequado para PEL. As estimativas de herdabilidade direta foram 0,17, 0,13, 0,20, 0,18, e 0,52 para PD, PE, CF, UM e PEL, respectivamente, o que indica a possibilidade de se obter progresso genético por meio da seleção para essas características, principalmente para PEL. As correlações genéticas aditivas diretas entre as características variaram de -0,16 a 0,61. As correlações entre PD e PE e entre PD e CF indicam que a seleção para PD deve proporcionar ganho genético em PE e CF Abstract in english The objective of this study was to establish the best-fit model for the genetic evaluation of Canchim cattle and to estimate the genetic parameters for productive characters at weaning. The data used were related to: 12,103 animals, for weight (PD); 5,278, for scrotal circumference (PE), 8,343, for [...] slaughter conformation visual score (CF); 9,111, for sheath and navel scores (UM), and 7,986, for hair coat score (PEL). Statistical models included fixed effects and random additive direct, maternal and maternal permanent environmental effects, in different combinations. The analyses were done by the derivative-free restricted maximum likelihood method. The complete model was the most suited for PD, PE, CF and UM, while the model with only additive direct and additive maternal random effects was the best for PEL. Direct heritability estimates were 0.17, 0.13, 0.20, 0.18, and 0.52 for PD, PE, CF, UM and PEL, respectively, which indicates that it is possible to obtain genetic progress through selection for these traits, mainly for PEL. The additive direct genetic correlations among traits varied from -0.16 to 0.61. The correlations between PD and PE and between PD and CF indicate that selection for PD should result in genetic gain in PE and CF

Fabiana, Barichello; Maurício Mello de, Alencar; Roberto Augusto de Almeida, Torres Júnior; Luiz Otávio Campos da, Silva.

218

Herdabilidade e correlações quanto a peso, perímetro escrotal e escores visuais à desmama, em bovinos Canchim Heritability and correlations for weight, scrotal circumference and visual scores at weaning, in Canchim beef cattle  

Directory of Open Access Journals (Sweden)

Full Text Available O objetivo deste trabalho foi estabelecer o modelo mais adequado para avaliação genética de bovinos Canchim e estimar os parâmetros genéticos de características produtivas à desmama. Foram utilizados dados de: 12.103 animais, quanto ao peso (PD; 5.278, quanto ao perímetro escrotal (PE; 8.343, quanto ao escore visual da conformação frigorífica (CF; 9.111, quanto ao escore de umbigo (UM; e 7.986, quanto ao escore de pelame (PEL. Os modelos estatísticos incluíram os efeitos fixos e os efeitos aleatórios genéticos aditivos direto, materno e de ambiente permanente materno, em diferentes combinações. As análises foram feitas pelo método da máxima verossimilhança restrita livre de derivadas. O modelo completo foi o mais adequado para PD, PE, CF e UM, enquanto o modelo com uso apenas dos efeitos genéticos aditivos direto e materno foi o mais adequado para PEL. As estimativas de herdabilidade direta foram 0,17, 0,13, 0,20, 0,18, e 0,52 para PD, PE, CF, UM e PEL, respectivamente, o que indica a possibilidade de se obter progresso genético por meio da seleção para essas características, principalmente para PEL. As correlações genéticas aditivas diretas entre as características variaram de -0,16 a 0,61. As correlações entre PD e PE e entre PD e CF indicam que a seleção para PD deve proporcionar ganho genético em PE e CFThe objective of this study was to establish the best-fit model for the genetic evaluation of Canchim cattle and to estimate the genetic parameters for productive characters at weaning. The data used were related to: 12,103 animals, for weight (PD; 5,278, for scrotal circumference (PE, 8,343, for slaughter conformation visual score (CF; 9,111, for sheath and navel scores (UM, and 7,986, for hair coat score (PEL. Statistical models included fixed effects and random additive direct, maternal and maternal permanent environmental effects, in different combinations. The analyses were done by the derivative-free restricted maximum likelihood method. The complete model was the most suited for PD, PE, CF and UM, while the model with only additive direct and additive maternal random effects was the best for PEL. Direct heritability estimates were 0.17, 0.13, 0.20, 0.18, and 0.52 for PD, PE, CF, UM and PEL, respectively, which indicates that it is possible to obtain genetic progress through selection for these traits, mainly for PEL. The additive direct genetic correlations among traits varied from -0.16 to 0.61. The correlations between PD and PE and between PD and CF indicate that selection for PD should result in genetic gain in PE and CF

Fabiana Barichello

2010-06-01

219

Correlation between the concentration of serum polychlorinated biphenyls (PCBs) in pregnant cynomolgus monkeys and their offspring's behavioral scores in eye-contact test and finger maze learning test  

Energy Technology Data Exchange (ETDEWEB)

A recent review suggested that pre- or perinatal exposure of developing fetuses to dioxins, the widespread environmental contaminants, such as polychrorinated biphenlys (PCBs), induce the irreversible abnormalities in the functions of central nervous system (CNS) in human. These chemicals can be transferred to each fetus and naonate transplacentally and lactationally in rhesus monkey. Several studies also reported the adverse effect of PCB on CNS development in rodents and monkeys as well as on behavior in rodents and monkeys. In the present study, we show a preliminary data about the correlation between the serum concentrations of PCBs in pregnant cynomolgus monkeys (Macaca fascicularis) and the scores of two behavioral tests, eye-contact test and four-step finger maze test, which evaluate consciousness against human observer and learning ability, respectively, in their offspring. This experimental surveillance system using non-human primates would be useful to predict the risk of PCBs exposure in human fetuses because of the similarities of cynomolgus monkey to human with regard to reproduction, developmental parameter, and others.

Negishi, T. [Aoyama Gakuin Univ., Kanagawa (Japan); Takasuga, T. [Shimadzu Techno-Research Inc., Kyoto (Japan); Kawasaki, K. [Hoshi Univ., Tokyo (Japan); Kuroda, Y. [CREST Japan Science and Technology Corp., Saitama (Japan); Yoshikawa, Y. [The Univ. of Tokyo (Japan)

2004-09-15

220

Prediction of bronchopulmonary dysplasia by chest radiographic scoring system at seven days of age  

Energy Technology Data Exchange (ETDEWEB)

Recent trials of preventive dexamethasone therapy in preterm neonates at high risk of developing bronchopulmonary dysplasia (BPD) have required the objective criteria for prediction of BPD in the early neonatal period. The purpose of this study is to determine whether a chest radiographic scoring system at 7 days of age can be used to predict BPD. Chest radiographs taken at 7 days and 28 days of age in 59 preterm neonates(gestational age of less than 33 weeks) were scored prospectively according to the consensus of two radiologists. The 7-day radiographs were scored according to a system derived from Yuksel's method:endotracheal tube insertion, degree of lung inflation, lung opacification, interstitial changes and cardiomegaly were measured. The radiographs taken at 28 days were scored according to a modification of Toce's method. The BPD group was defined as consisting of patients who needed oxygen therapy for more than 28 days and showed abnormality on chest radiographs. Scores were analysed to determine whether there were any statistical differences between the BPD and non-BPD groups, whether there was a significant correlation between scores at 7 days and 28 days, and whether there was any relationship between scores at 7 days of age and the development of BPD. We tried to determine which factors, as indicated by the scores at 7 days, significantly contributed to the development of BPD. The mean scores at 7 days of age in the BPD group (n=18) were 4.3{+-}1.5 (2-7), and those in the non-BPD group (n=41) were 2.2{+-}1.2 (0-4). The differences were statistically significant (p<.0001). Significant correlation was found between scores at 7 days and at 28 days of age(r:0.57, p<.0001). Analysis showed that endotracheal tube insertion, cardiomegaly, and degree of interstitial change, as seen on radiographs at 7 days, were factors which significantly contributed to the development of BPD (p<0.05 each). All neonates with a score of 5 or more developed BPD (7/7), while those with a score of less than 2 did not (0/11). The chest radiographic scoring system used at 7 days of age can be helpful in predicting the development of BPD. We believe that this system can be used to indicate the need for early preventive steroid therapy.

Choi, Yun Sun; Kim, Woo Sun; Kim, In One; Choi, Jung Hwan; Yeon, Kyung Mo; Yun, Chong Ku [Seoul National Univ. College of Medicine, Seoul (Korea, Republic of)

1997-03-01

 
 
 
 
221

Relationships between childhood maltreatment, parenting style, and borderline personality disorder criteria.  

Science.gov (United States)

This study examines the relationship of different types of childhood maltreatment and the perceived parenting style with borderline personality disorder (BPD) criteria. Kendall's Tau partial correlations were performed controlling for the effect of simultaneous adverse experiences and Axis I and II symptoms in a sample of 109 female patients (32 BPD, 43 other personality disorder, and 34 non-personality disorder). BPD criteria were associated with higher scores on emotional and sexual abuse, whereas parenting style did not show a specific association with BPD. Findings of the present study help clarify the effects of overlapping environmental factors that are associated with BPD. PMID:23013341

Hernandez, Ana; Arntz, Arnoud; Gaviria, Ana M; Labad, Antonio; Gutiérrez-Zotes, José Alfonso

2012-10-01

222

Use of Z-scores to rank applicants to professional degree programs.  

Science.gov (United States)

Criteria for assessing suitability of applicants for professional degree programs such as veterinary medicine are usually treated as distinct components of a composite scoring procedure that determines applicant ranking. Some components are valued more than others, which is reflected in the relative weights assigned to each component. However, the patterns of dispersal of individual components have the potential to alter the assigned relative weights. Components with larger variances can have greater influences on composite scores than intended. Such unintended altered weighting can be avoided through standardization. Yet non-standardized approaches continue to be used for admissions ranking in several programs. In this study, we documented the potential for differential selection of applicants when non-standardized scoring approaches are applied to admissions assessment components. At our medical school, applicants' component scores with differing variances are standardized by determining Z-scores with a mean of 0 and standard deviation of 1 before mathematically combining to calculate composite scores and admissions ranking. We retrospectively and hypothetically ranked one applicant cohort using non-standardized methods and identified differences in ranking between the standardized and non-standardized approaches. Most differences were observed for applicants in the second, third, and fourth quintiles of the admissions rank list, that is, those for whom admissions cut-off decisions make a marked difference. Observations were supported by lower Spearman's rank correlation coefficients in these quintiles. Although standardization of component scores is not a novel topic, we document the implications of using non-standardized scoring approaches for applicant ranking and underscore the importance of standardization of component scores. PMID:23475414

Raghavan, Malathi; Martin, Bruce D; Aoki, Fred; Mackalski, Barbara; Christensen, Heather

2013-01-01

223

Interpreting force concept inventory scores: Normalized gain and SAT scores  

Science.gov (United States)

Preinstruction SAT scores and normalized gains (G) on the force concept inventory (FCI) were examined for individual students in interactive engagement (IE) courses in introductory mechanics at one high school (N=335) and one university (N=292) , and strong, positive correlations were found for both populations ( r=0.57 and r=0.46 , respectively). These correlations are likely due to the importance of cognitive skills and abstract reasoning in learning physics. The larger correlation coefficient for the high school population may be a result of the much shorter time interval between taking the SAT and studying mechanics, because the SAT may provide a more current measure of abilities when high school students begin the study of mechanics than it does for college students, who begin mechanics years after the test is taken. In prior research a strong correlation between FCI G and scores on Lawson’s Classroom Test of Scientific Reasoning for students from the same two schools was observed. Our results suggest that, when interpreting class average normalized FCI gains and comparing different classes, it is important to take into account the variation of students’ cognitive skills, as measured either by the SAT or by Lawson’s test. While Lawson’s test is not commonly given to students in most introductory mechanics courses, SAT scores provide a readily available alternative means of taking account of students’ reasoning abilities. Knowing the students’ cognitive level before instruction also allows one to alter instruction or to use an intervention designed to improve students’ cognitive level.

Coletta, Vincent P.; Phillips, Jeffrey A.; Steinert, Jeffrey J.

2007-06-01

224

Finishing precocity visual score and genetic associations with growth traits in Angus beef cattle.  

Science.gov (United States)

Finishing precocity visual score selection was adopted to estimate the time from birth to reach slaughter age. This study estimated (co)variance components and genetic correlations for the finishing precocity score at weaning (WP) and yearling (YP) stages by using daily weight gain (BWG = from birth to weaning; WYG = from weaning to yearling) and speed of weight gain (BWR = from birth to weaning; WYR = from weaning to yearling) as support for a genetic evaluation program for Angus beef cattle. Genetic parameters were estimated using Bayesian inference, considering multi-trait analysis and assuming a nonlinear model for WP and YP and linear model for all other traits. Direct heritability estimates were 0.17 (WP), 0.19 (YP), 0.15 (BWG), 0.16 (WYG), 0.15 (BWR), and 0.16 (WYR). The genetic correlation between the finishing precocity score at two ages (weaning and yearling) was 0.61. Positive and moderate genetic correlations were obtained between WP and BWG (0.47) and WP and BWR (0.46). In contrast, negative and low genetic associations were estimated between WP and yearling growth traits (-0.16, WYG; -0.15, WYR). Genetic correlations between YP and other traits were positive 0.29 (BWG), 0.28 (BWR), 0.48 (WYG), and 0.47 (WYR). The selection response for the finishing precocity score at weaning and yearling ages would be low. Selection to increase WP and YP should result in favorable genetic changes in daily weight gains as a correlated response. Therefore, to obtain animals suited for beef cattle production systems, finishing precocity score and growth traits should be considered as selection criteria. PMID:25299089

Everling, D M; Bresolin, T; Rorato, P R N; Araujo, R O; Boligon, A A; Weber, T; Dornelles, M A; Campos, L T

2014-01-01

225

7 CFR 1703.126 - Criteria for scoring grant applications.  

Science.gov (United States)

...Empowerment Zone and Enterprise Communities) and...implementing, and financial assistance...or health care challenges facing the community...to address these challenges; how the grant...or health care challenges could not be...include letters of financial commitment...

2010-01-01

226

7 CFR 1703.126 - Criteria for scoring grant applications.  

Science.gov (United States)

...should reflect any additional financial support for the project...reflecting accepted analytical and financial methodologies to substantiate...ability to connect to the Internet alone cannot be used as the...facilities being constructed with financial assistance,...

2010-01-01

227

7 CFR 1703.126 - Criteria for scoring grant applications.  

Science.gov (United States)

...the applicable percentage of students eligible to participate...application: (A) Public schools or non-profit private schools of high school grade or under...eligibility percentage of all students in the school district...

2010-01-01

228

7 CFR 1703.126 - Criteria for scoring grant applications.  

Science.gov (United States)

...particular school. (B) Schools and institutions of higher...participate in the NSLP and non-school end user sites (medical facilities, libraries, etc.) will use the eligibility...percentage of all students in the school district where the end...

2010-01-01

229

Summary of the criteria and scoring scheme adopted by the ...  

with basic Microsoft Excel skills. Further details about the project are ..... shops, \\community, tourism, shows, sports events, riding schools etc). ..... years and there \\is little institutional memory associated with controlling the disease OR legislation\\ ...

230

7 CFR 1703.126 - Criteria for scoring grant applications.  

Science.gov (United States)

...Applications for grants must meet the rurality requirements in paragraph (b)(2...55 points); (2) The comparative rurality of the project service area (up to 45...Agriculture. (2) The comparative rurality of the project service area—Up to...

2010-01-01

231

7 CFR 1703.126 - Criteria for scoring grant applications.  

Science.gov (United States)

...extent to which the application is consistent with the State strategic plan prepared by the Rural Development State Director of the...facilities, RUS will consider documentation explaining the necessity of this option. RUS will also consider any agreements...

2010-01-01

232

7 CFR 1703.126 - Criteria for scoring grant applications.  

Science.gov (United States)

...specified number of students; (2 ) Travel time...Number of additional students electing to attend higher...public forums, and surveys. In addition, applicants...addresses the problems of population out-migration and...applicable percentage of students eligible to...

2010-01-01

233

7 CFR 1703.126 - Criteria for scoring grant applications.  

Science.gov (United States)

...education, or health care challenges facing the community; the...proposed plan to address these challenges; how the grant can help...education, or health care challenges could not be addressed...consistent with the State strategic plan prepared by the...

2010-01-01

234

A systematic review study of therapeutic intervention scoring system — 28  

Directory of Open Access Journals (Sweden)

Full Text Available Objective: to show the effectiveness of TISS – 28 in the evaluation of patient severity and the nursing work load in ICU’s. Methodology: this is a systematic review in six electronic database and a reverse literature review, 38 abstracts of interest were found, selected by criteria of eligibility and quality. Eighteen studies were considered eligible, of which sixteen were primary and two meta-analyses. Results: TISS – 28 made it possible to estimate the severity of the patients, evaluate the nursing workload, as well as to show the frequency between death and high values of this score in ICU’s. Conclusion: the instrument is highly correlated with the original version, practical and easy to use, making possible the relevant evaluation of the severity of the patient and the nursing work load, as well as to assist in planning personnel and materials for a more humanized and quality care.

Daniela Soares Santos, Tânia Couto Machado Chianca, Andreza Werli

2010-04-01

235

Reporting Valid and Reliable Overall Scores and Domain Scores  

Science.gov (United States)

In educational assessment, overall scores obtained by simply averaging a number of domain scores are sometimes reported. However, simply averaging the domain scores ignores the fact that different domains have different score points, that scores from those domains are related, and that at different score points the relationship between overall…

Yao, Lihua

2010-01-01

236

Comparison of Prognosis in Patients with Liver Cirrhosis and its Correlation with the Model for the End-Stage Liver Disease and Child-PughChild-Pugh Scores in Patients with Esophageal or Gastric Variceal Bleeding  

Directory of Open Access Journals (Sweden)

Full Text Available Background:Variceal bleeding is one of the most serious complications of cirrhosis. Up to now different methods are created for predicting the complications and mortality of cirrhosis. Child- Pugh score and MELD score are two methods for this use. In this study we investigated and compared survival prognosis of cirrhotic patients by the Child-Pugh or MELD score in two groups of esophageal and gastric variceal bleeding. Materials and Methods: In this cross-sectional trial, patients with upper GI bleeding were followed up for a 6 months period. The source of hemorrhage was determined by endoscopy, then patients distributed in two groups of esophageal and gastric variceal hemorrhage. Finally we investigated and compared the relationship between the variables and mortality rates in these two groups by means of the Child-Pugh and the MELD scores. The Student’s t-test and Receiver Operating Characteristic were used for statistical analysis.Results: 34 patients (12 with gastric varices, 22 with esophageal varices were investigated. No significant difference between these two groups was observed. In this study mean MELD score was 16.67±8.75 and mean Child-Pugh score was 9.37±2.54. Eight patients (5 with gastric varices and 3 with esophageal varices expired before 6 weeks and 2 patients (one four each group expired after 6 weeks. The best cut-off points are 15.5 and 10.5 for MELD and Child-Pugh scores respectively (sensitivity and specificity are 0.75 and 0.98, respectively for both scores.Conclusion:Sensitivity and specificity of both scores were the same in prediction of mortality. However, the chance ratio defined that Child-Pugh score was a better predictor of mortality than MELD score, since the chance of death will increase 2.51 and 1.62 fold per each unit increase in the Child-Pugh and the MELD scores, respectively. However, no significant difference found between Child-Pugh and MELD score between two groups of patients.

Mohammadreza Sheikhian

2013-09-01

237

Teaching Performance Criteria to Students  

Science.gov (United States)

This is one chapter from a textbook entitled Scoring Rubrics in the Classroom: Using Performance Criteria for Assessing and Improving Student Performance. In this chapter, the authors link assessment and instruction by exploring the use of rubrics as instructional tools to involve students in their own assessment and improve student performance. Practical strategies for teaching performance criteria to students, involving students in peer and self-assessment, providing student-friendly feedback, and the instructional use of anchors are offered. The guiding question is: How can we use rubrics to improve, as well as judge, student performance?

238

Prospective validation of the “rhino conjunctivitis allergy-control-SCORE©” (RC-ACS©  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Recently we reported the validation of the “Allergy-Control-SCORE© (ACS” which assesses symptom severity as well as medication use on three dimensions lung, nose and eyes. The aim of this study was to test the validity of the score for eyes and nose. Methods One-hundred-twenty-one consenting subjects (age 19-65y, including 81 patients with allergic rhino-conjunctivitis (RC and 40 healthy controls, participated in the study. Patients rated daily nasal and eye symptoms using a 4-point scale (none, mild, moderate, and severe and their use of anti-symptomatic medication. Validation criteria were pollen counts in the course of the study period. Discrimination capacity was analyzed by comparing the rhino-conjunctivitis Allergy-Control-SCORE© (RC-ACS© values of allergic patients and healthy controls. Convergent reliability was assessed by correlating RC-ACS© values with the global severity of allergy, the quality of life, and the allergy-related medical consultations. Retest reliability was assessed by the correlation of the repeated measured RC-ACS© scores during each of two consecutive weeks. Results Convergent reliability analysis indicated a significant correlation between RC-Allergy-Control-SCORE© and global severity of allergy (r?=?0.691; p?r?=?0.757; p?r?=?0.329; p?=?0.0019. RC-Allergy-Control-SCORE© showed a good retest reliability (r?=?0.813; p? Conclusions The RC-ACS© can be considered as valid and reliable to assess the severity of rhino-conjunctivitis severity in clinical trials and observational studies.

Häfner Dietrich

2012-09-01

239

Thrombotic risk assessment in APS: the Global APS Score (GAPSS).  

Science.gov (United States)

Recently, we developed a risk score for antiphospholipid syndrome (APS) (Global APS Score or GAPSS). This score derived from the combination of independent risk factors for thrombosis and pregnancy loss, taking into account the antiphospholipid antibodies (aPL) profile (criteria and non-criteria aPL), the conventional cardiovascular risk factors, and the autoimmune antibodies profile. We demonstrate that risk profile in APS can be successfully assessed, suggesting that GAPSS can be a potential quantitative marker of APS-related clinical manifestations. PMID:25228728

Sciascia, S; Bertolaccini, Ml

2014-10-01

240

La evaluación de revistas de psicología: correlación entre el factor de impacto, el índice h y los criterios de Latindex / Assessment of psychology journals: correlation of impact factor and h-index vs. Latindex criteria  

Scientific Electronic Library Online (English)

Full Text Available SciELO Mexico | Language: Spanish Abstract in spanish El objetivo de este trabajo fue comprobar el grado en que dos criterios basados en el recuento de citas, como el factor de impacto propuesto por el Journal Citation Reports y el índice h de Hirsch (2005), y otro criterio más relacionado con la calidad del proceso editorial, como el grado de cumplimi [...] ento de los criterios propuestos por el catálogo Latindex, ordenan de forma similar un conjunto de revistas de psicología. Utilizamos estos tres criterios para confeccionar sendas clasificaciones de estas revistas y encontramos que la correlación entre la clasificación Latindex y cualquiera de las otras dos no fue significativamente distinta de cero. Se discute la conveniencia de disponer de criterios ajenos al recuento de citas para evaluar la calidad de las revistas científicas de psicología y se propone el uso combinado de criterios como la difusión, la internacionalidad, el proceso de revisón de los manuscritos o la política editorial de la revista. Abstract in english The goal of this study is to explore the extent to which several psychology journals may be similarly classified on the basis of citation count through the impact factor proposed by Journal Citation Reports and the hindex (Hirsch, 2005), against a given journal's compliance with the Latindex Catalog [...] ue criteria for assessing editorial quality. Using these parameters, we carried out three separate journal rankings and found that the correlation between the Latindex ranking and either of the former is not statistically distinct from zero. The suitability of applying editorial- rather than citation-based criteria to evaluate the quality of psychology journals is discussed. This discussion proposes using a mix of editorial criteria such as circulation, international reach and the journal's manuscript review process and editorial policies.

A. Matías, Gámez.

2013-12-01

 
 
 
 
241

score-network.org  

... score-network.org 24 February 2014 Consumption opportunities: strategies for change UNEP This paper discusses the strategies, means and ways to make the change to sustainable consumption . 2000 UNEP, Geneva, Switzerland attachment (pdf 629K) ...

242

Nutrient Density Scores.  

Science.gov (United States)

Announces a nutrient density food scoring system called the Index of Nutritional Quality (INQ). It expresses the ratio between the percent RDA of a nutrient and the percent daily allowance of calories in a food. (Author/SA)

Dickinson, Annette; Thompson, William T.

1979-01-01

243

The Bayesian Score Statistic  

Digital Repository Infrastructure Vision for European Research (DRIVER)

We propose a novel Bayesian test under a (noninformative) Je?reys’ prior speci?ca- tion. We check whether the ?xed scalar value of the so-called Bayesian Score Statistic (BSS) under the null hypothesis is a plausible realization from its known and standard- ized distribution under the alternative. Unlike highest posterior density regions the BSS is invariant to reparameterizations. The BSS equals the posterior expectation of the classical score statistic and it pro...

Kleibergen, F. R.; Kleijn, R. H.; Paap, R.

2000-01-01

244

Malnutrition-Inflammation Score in Hemodialysis Patients  

Directory of Open Access Journals (Sweden)

Full Text Available Background: Malnutrition is a prevalent complication in patients on maintenance hemodialysis. Malnutrition-inflammation score (MIS, comprehensive nutritional assessment tool, as the reference standard was used to examine protein-energy wasting (PEW and inflammation in hemodialysis patients. Materials and Methods: In this descriptive- analytical study, 48 hemodialysis patients were selected with random sampling. All the patients were interviewed and the MIS of the patients was recorded. This new comprehensive Malnutrition-Inflammation Score (MIS which involves 7 components from the SGA and the 3 additional non-SGA components of body mass index, serum albumin, and total iron-binding capacity (TIBC has 10 components, each with four levels of severity, from 0 (normal to 3 (very severe. These scores were compared with anthropometric measurements; laboratory measures. Data was analyzed with Chi-square and t-tests and Pearson correlation coefficiant. Results: In this study 25% of patients on hemodialysis were normal nourished, 54.3% of patients were mild malnourished, 20.8% were moderately malnourished and no one of them were not sever malnurished. Pearson correlation coefficients between MIS score and age (r=+0.332 was significant. There was no correlation between the malnutrition score and sex Chi-square test showed significant correlation between MIS score and dialysis period ?50 months (?²=9.09. Conclusion: In this study, no one of patients has severed malnutrition, and most of them were assigned to the mildly/moderately malnourished rating. On other hand, most of patients are the well-nourished. Correlation between MIS score and age and dialysis period was significant.

Behrooz Ebrahimzadehkor

2014-08-01

245

Satisfaction in hospitality on TripAdvisor.com: An analysis of the correlation between evaluation criteria and overall satisfaction / A satisfação na hotelaria pelo TripAdvisor: uma análise da correlação entre os critérios de avaliação e satisfação geral  

Scientific Electronic Library Online (English)

Full Text Available SciELO Portugal | Language: English Abstract in portuguese As mídias sociais alteraram a forma dos turistas buscarem e trocarem informações, determinando mudanças gerenciais para as empresas turísticas, incluindo os meios de hospedagem. Os comentários e avaliações de hóspedes têm impactado na reputação das organizações, tanto positivamente como negativament [...] e. Os sítios de conteúdo gerado pelos usuários permitem que estas informações cheguem a outros turistas, através da avaliação do serviço prestado e influenciando na decisão de novos visitantes. Desta forma, esta investigação procurou identificar a correlação entre a satisfação geral e os critérios de avaliação. Para isto, foram analisadas 660 avaliações (236 nos hotéis 03 estrelas, 125 nos hotéis 04 estrelas e 299 nos hotéis 05 estrelas) no Tripadvisor, que continham de forma independente, avaliações sobre: satisfação geral, valor (custo-benefício), localização, qualidade do sono, quartos, limpeza e serviço. Os resultados apontaram para um maior índice de correlação da satisfação geral com os critérios quarto, serviço ofertado e custo-benefício. Abstract in english Social media has changed the way tourists seek and exchange information, resulting in changes in the management of tourism businesses including hospitality facilities. Guest reviews and comments have had an impact on the reputation of organisations, both positive and negative. Websites with user-gen [...] erated content spread this information to other tourists through the evaluation of service provided and thereby influence the decision of new visitors. Accordingly, this research sought to identify the correlation between overall satisfaction and the evaluation criteria used on a website. For this, we analysed 660 reviews (236 of three-star hotels, 125 of four-star hotels and 299 of five-star hotels) on TripAdvisor, containing independent reviews including overall satisfaction, value (cost-benefit), location, sleep quality, rooms, cleanliness and service. Results showed a strong correlation of overall satisfaction with the criteria of room, service provided and cost-benefit.

Pablo Flôres, Limberger; Francisco Antonio dos, Anjos; Jéssica Vieira de Souza, Meira; Sara Joana Gadotti dos, Anjos.

2014-01-01

246

Node-by-node correlation between MR and PET/CT in patients with uterine cervical cancer: diffusion-weighted imaging versus size-based criteria on T2WI  

International Nuclear Information System (INIS)

The purpose of the study was to perform a node-by-node comparison of an ADC-based diagnosis and various size-based criteria on T2-weighted imaging (T2WI) with regard to their correlation with PET/CT findings in patients with uterine cervical cancer. In 163 patients with 339 pelvic lymph nodes (LNs) with short-axis diameter >5 mm, the minimum apparent diffusion coefficient (ADC), mean ADC, short- and long-axis diameters, and ratio of long- to short-axis diameters (L/S ratio) were compared in PET/CT-positive and -negative LNs. On PET/CT, 118 (35%) LNs in 58 patients were positive. The mean value of minimum and mean ADCs, short- and long-axis diameters, and L/S ratio were different in PET/CT-positive (0.6436 x 10-3 mm2/s, 0.756 x 10-3 mm2/s, 10.3 mm, 13.2 mm, 1.32, respectively) and PET/CT-negative LNs (0.8893 x 10-3 mm2/s, 1.019 x 10-3 mm2/s, 7.4 mm, 11.0 mm, 1.49, respectively) (P<0.05). The Az value of the minimum ADC (0.864) was greater than those of mean ADC (0.836), short-axis diameter (0.764), long-axis diameter (0.640) and L/S ratio (0.652) (P<0.05). The sensitivity and accuracy of the minimum ADC (86%, 82%) were greater than those of the short-axis diameter (55%, 74%), long-axis diameter (73%, 58%) and L/S ratio (52%, 66%) (P<0.05). ADC showed superior correlation with PET/CT compared with conventional size-based criteria on T2WI. (orig.)ig.)

247

Satisfaction in hospitality on TripAdvisor.com: An analysis of the correlation between evaluation criteria and overall satisfaction / A satisfação na hotelaria pelo TripAdvisor: uma análise da correlação entre os critérios de avaliação e satisfação geral  

Scientific Electronic Library Online (English)

Full Text Available SciELO Portugal | Language: English Abstract in portuguese As mídias sociais alteraram a forma dos turistas buscarem e trocarem informações, determinando mudanças gerenciais para as empresas turísticas, incluindo os meios de hospedagem. Os comentários e avaliações de hóspedes têm impactado na reputação das organizações, tanto positivamente como negativament [...] e. Os sítios de conteúdo gerado pelos usuários permitem que estas informações cheguem a outros turistas, através da avaliação do serviço prestado e influenciando na decisão de novos visitantes. Desta forma, esta investigação procurou identificar a correlação entre a satisfação geral e os critérios de avaliação. Para isto, foram analisadas 660 avaliações (236 nos hotéis 03 estrelas, 125 nos hotéis 04 estrelas e 299 nos hotéis 05 estrelas) no Tripadvisor, que continham de forma independente, avaliações sobre: satisfação geral, valor (custo-benefício), localização, qualidade do sono, quartos, limpeza e serviço. Os resultados apontaram para um maior índice de correlação da satisfação geral com os critérios quarto, serviço ofertado e custo-benefício. Abstract in english Social media has changed the way tourists seek and exchange information, resulting in changes in the management of tourism businesses including hospitality facilities. Guest reviews and comments have had an impact on the reputation of organisations, both positive and negative. Websites with user-gen [...] erated content spread this information to other tourists through the evaluation of service provided and thereby influence the decision of new visitors. Accordingly, this research sought to identify the correlation between overall satisfaction and the evaluation criteria used on a website. For this, we analysed 660 reviews (236 of three-star hotels, 125 of four-star hotels and 299 of five-star hotels) on TripAdvisor, containing independent reviews including overall satisfaction, value (cost-benefit), location, sleep quality, rooms, cleanliness and service. Results showed a strong correlation of overall satisfaction with the criteria of room, service provided and cost-benefit.

Pablo Flôres, Limberger; Francisco Antonio dos, Anjos; Jéssica Vieira de Souza, Meira; Sara Joana Gadotti dos, Anjos.

248

Geometric facial gender scoring: objectivity of perception.  

Science.gov (United States)

Gender score is the cognitive judgement of the degree of masculinity or femininity of a face which is considered to be a continuum. Gender scores have long been used in psychological studies to understand the complex psychosocial relationships between people. Perceptual scores for gender and attractiveness have been employed for quality assessment and planning of cosmetic facial surgery. Various neurological disorders have been linked to the facial structure in general and the facial gender perception in particular. While, subjective gender scoring by human raters has been a tool of choice for psychological studies for many years, the process is both time and resource consuming. In this study, we investigate the geometric features used by the human cognitive system in perceiving the degree of masculinity/femininity of a 3D face. We then propose a mathematical model that can mimic the human gender perception. For our experiments, we obtained 3D face scans of 64 subjects using the 3dMDface scanner. The textureless 3D face scans of the subjects were then observed in different poses and assigned a gender score by 75 raters of a similar background. Our results suggest that the human cognitive system employs a combination of Euclidean and geodesic distances between biologically significant landmarks of the face for gender scoring. We propose a mathematical model that is able to automatically assign an objective gender score to a 3D face with a correlation of up to 0.895 with the human subjective scores. PMID:24923319

Gilani, Syed Zulqarnain; Rooney, Kathleen; Shafait, Faisal; Walters, Mark; Mian, Ajmal

2014-01-01

249

Geometric Facial Gender Scoring: Objectivity of Perception  

Science.gov (United States)

Gender score is the cognitive judgement of the degree of masculinity or femininity of a face which is considered to be a continuum. Gender scores have long been used in psychological studies to understand the complex psychosocial relationships between people. Perceptual scores for gender and attractiveness have been employed for quality assessment and planning of cosmetic facial surgery. Various neurological disorders have been linked to the facial structure in general and the facial gender perception in particular. While, subjective gender scoring by human raters has been a tool of choice for psychological studies for many years, the process is both time and resource consuming. In this study, we investigate the geometric features used by the human cognitive system in perceiving the degree of masculinity/femininity of a 3D face. We then propose a mathematical model that can mimic the human gender perception. For our experiments, we obtained 3D face scans of 64 subjects using the 3dMDface scanner. The textureless 3D face scans of the subjects were then observed in different poses and assigned a gender score by 75 raters of a similar background. Our results suggest that the human cognitive system employs a combination of Euclidean and geodesic distances between biologically significant landmarks of the face for gender scoring. We propose a mathematical model that is able to automatically assign an objective gender score to a 3D face with a correlation of up to 0.895 with the human subjective scores. PMID:24923319

Gilani, Syed Zulqarnain; Rooney, Kathleen; Shafait, Faisal; Walters, Mark; Mian, Ajmal

2014-01-01

250

Decisions during courtship by male and female medflies (Diptera, Tephritidae): Correlated changes in male behavior and female acceptance criteria in mass-reared flies  

International Nuclear Information System (INIS)

Analyses of more than 300 videotaped courtships of wild and mass-reared medflies from Costa Rica showed that the tendency for male and female to align themselves facing directly toward each other increased, and that the distance between them decreased as courtship proceeded. More direct alignments and shorter distances between the flies at the moment the male jumped onto the female were correlated with greater female acceptance of copulation. There were no consistent differences in durations of components of intermittent buzzing songs or male size between successful and unsuccessful courtship in either strain. Several possible cues may release different courtship responses: males of both strains tend to initiate both continuous vibration and intermittent buzzing after reduction of the distance to the female; slow creeping toward the female was associated with longer courtships that had failed to lure the female close; and females tended to turn to face more directly toward the male soon after the male began continuous vibration, and especially after he began intermittent buzzing. Females became progressively more immobile as courtship progressed, especially soon after intermittent buzzing began. There were numerous differences between strains. Mass-reared males were more likely to mount females without previous courtship than were wild males. Wild males initiated continuous wing vibration when farther from the female and when the female was looking less directly towarthe female was looking less directly toward them, but the two strains did not differ in the distances and angles at which males initiated intermittent buzzing and jumped. Wild males were more likely to creep toward the female during intermittent buzzing. Mass-reared females but not wild females were more likely to copulate when the proportion of time the male had spent in intermittent buzzing was low, and if the courtship began when the flies were nearer each other. Wild but not mass-reared females were less likely to copulate if courtship was shorter. Possible co-evolution of female responses with the five different male courtship traits that differ between mass-reared and wild flies are discussed. (author)

251

A Study of Relationships between the CI Scores (E-C of High-score & Low-score Groups and Their Language Learning Strategies  

Directory of Open Access Journals (Sweden)

Full Text Available This paper investigates the relationships between language learning strategies and consecutive interpretation (CI scores (E-C of 120 English major students in China through a quantitative study. The analysis shows that there exist significant differences of using meta-cognitive strategy and cognitive strategy between high-score group and low-score group, sub-CI scores are positively correlated with the two strategies, and meta-cognitive strategy can positively predict the total scores. This indicates that the use of language learning strategies does have an impact on interpreting study.

Jianjun Liu

2011-10-01

252

Introduction of a new standardized assessment score of spine morphology in osteogenesis imperfecta  

Energy Technology Data Exchange (ETDEWEB)

Purpose: Osteogenesis imperfecta (OI) is a rare hereditary disease leading to multiple bone deformities and fractures. In the absence of causal therapy, a symptomatic approach is based on treatment with bisphosphonates and physiotherapy. The clinical and radiological manifestations vary. Therefore, standardization and quantification for an objective comparison, especially during therapy, are required. In this paper, radiological changes of the spine are quantified according to their clinical relevance to define a scoring system that transfers the morphological changes into a single value representing the severity of the disease. Materials and Methods: 268 lateral spine X-rays of 95 patients with OI (median age 5.6 years) were assessed. The findings were classified based on their clinical relevance. Results: The three criteria, vertebral compression, thoracolumbar kyphosis and deformity type, were quantified in a new grading system. Based on this, a 'severity classification' (1 to 5) was defined with implications for diagnostics and treatment. A mathematical formula that takes into account the three criteria and their correlations to clinical relevance, resulting in a 'severity score', was developed. Conclusion: 'Severity classification' and 'severity score' introduce a new concept for a standardized evaluation of spine X-rays in patients with OI. For both scientific and routine purposes, it provides the user with a simple and easy-to-handle tool for assessing and comparing different stages of severity prior to and during therapy with detailed accuracy. (orig.)

Koerber, F.; Schulze Uphoff, U.; Koerber, S.; Maintz, D. [Koeln Univ. (Germany). Dept. of Radiology; Schoenau, E.; Semler, O. [Koeln Univ. (Germany). Children' s Hospital

2012-08-15

253

Introduction of a new standardized assessment score of spine morphology in osteogenesis imperfecta  

International Nuclear Information System (INIS)

Purpose: Osteogenesis imperfecta (OI) is a rare hereditary disease leading to multiple bone deformities and fractures. In the absence of causal therapy, a symptomatic approach is based on treatment with bisphosphonates and physiotherapy. The clinical and radiological manifestations vary. Therefore, standardization and quantification for an objective comparison, especially during therapy, are required. In this paper, radiological changes of the spine are quantified according to their clinical relevance to define a scoring system that transfers the morphological changes into a single value representing the severity of the disease. Materials and Methods: 268 lateral spine X-rays of 95 patients with OI (median age 5.6 years) were assessed. The findings were classified based on their clinical relevance. Results: The three criteria, vertebral compression, thoracolumbar kyphosis and deformity type, were quantified in a new grading system. Based on this, a 'severity classification' (1 to 5) was defined with implications for diagnostics and treatment. A mathematical formula that takes into account the three criteria and their correlations to clinical relevance, resulting in a 'severity score', was developed. Conclusion: 'Severity classification' and 'severity score' introduce a new concept for a standardized evaluation of spine X-rays in patients with OI. For both scientific and routine purposes, it provides the user with a simple and easy-to-handle tool for assessing and compeasy-to-handle tool for assessing and comparing different stages of severity prior to and during therapy with detailed accuracy. (orig.)

254

Correlation between Teacher Turnover Rates in the State of Alaska and Standardized Test Scores in the Area of Mathematics on the Standards Based Assessments/High School Qualifying Exam  

Science.gov (United States)

This study utilized bivariate correlations, partial correlations, multivariate analysis including Hotelling-T, and observed power to investigate the possible correlations and connections of teacher turnover in Alaska's public school system to performance on the standards-based assessment of the Alaska High School Qualifying Exam (HSQE). The study…

Roehl, Roy F., II

2010-01-01

255

Interpreting FCI scores: Normalized gain, preinstruction scores, and scientific reasoning ability  

Science.gov (United States)

We examined normalized gains and preinstruction scores on the force concept inventory (FCI) for students in interactive engagement courses in introductory mechanics at four universities and found a significant, positive correlation for three of them. We also examined class average FCI scores of 2948 students in 38 interactive engagement classes, 31 of which were from the same four universities and 7 of which came from 3 other schools. We found a significant, positive correlation between class average normalized FCI gains and class average preinstruction scores. To probe this correlation, we administered Lawson's classroom test of scientific reasoning to 65 students and found a significant, positive correlation between these students' normalized FCI gains and their Lawson test scores. This correlation is even stronger than the correlation between FCI gains and preinstruction FCI scores. Our study demonstrates that differences in student populations are important when comparing normalized gains in different interactive engagement classes. We suggest using the Lawson test along with the FCI to measure the effectiveness of alternative interactive engagement strategies.

Coletta, Vincent P.; Phillips, Jeffrey A.

2005-12-01

256

Instant MuseScore  

CERN Document Server

Get to grips with a new technology, understand what it is and what it can do for you, and then get to work with the most important features and tasks. Instant MuseScore is written in an easy-to follow format, packed with illustrations that will help you get started with this music composition software.This book is for musicians who would like to learn how to notate music digitally with MuseScore. Readers should already have some knowledge about musical terminology; however, no prior experience with music notation software is necessary.

Shinn, Maxwell

2013-01-01

257

Ki-67 expression score correlates to survival rate in gastrointestinal stromal tumors (GIST Escore de expressão de Ki-67 correlaciona-se com taxa de sobrevida em tumores estromais gastrointestinais (GIST  

Directory of Open Access Journals (Sweden)

Full Text Available PURPOSE: To evaluate the immunohistochemical expression of p16, Ki-67, p53 and Bcl-2 proteins in gastrointestinal stromal tumors (GIST; to assess the possible association between these variables and clinical and histopathological factors of cancer; and to check for prognostic value of these variables (survival and recurrence. METHODS: A sample of 55 patients treated surgically for GIST in three hospitals was studied. The surgically excised tumors were confirmed as GIST by KIT, vimentin, desmin S100 protein, CD117, 1A4 and CD34 assessment in paraffin blocks. RESULTS: Only 9 (16% cases of GIST were positive for p53, p16 was positive among 43.6%; 80% of GISTs showed staining for Bcl-2. The proliferative index (expressed as the proportion of positive cells assessed by immunohistochemical expression of Ki-67 was high in 49% of cases. Elevated Ki-67 scores were associated to high histological grade (p=0.0026 and mitosis index, MI (p=0.0001. High Ki-67 index was associated to death. Expression of p53, p16 and Bcl-2 did not correlate to morphological or clinical variables. CONCLUSIONS: Ki-67 immunohistochemical evaluation should be included in preoperative evaluation of GIST biopsies or surgical specimens as a prognostic tool for clinical staging; and all other proteins studied (Bcl-2, p53 and p16 did not play a role in GIST metabolic or carcinogenic process, remaining without prognostic value.OBJETIVO: Avaliar a expressão imunoistoquímica de p16, Ki-67, p53 e Bcl-2 proteínas em tumores gastrointestinais estromais (GIST; determinar a possível associação entre essas variáveis e fatores clínicos e histopatológicos de câncer, e para verificar o valor prognóstico destas variáveis (sobrevivência e recorrência. MÉTODOS: Uma amostra de 55 pacientes tratados cirurgicamente para GIST em três hospitais foi estudada. Os tumores extirpados cirurgicamente foram confirmados como GIST por KIT, vimentina, proteína desmina S100, CD117, 1A4 e avaliação de CD34 em blocos de parafina. RESULTADOS: Apenas nove (16% casos de GIST foram positivos para p53, p16 foi positiva em 43,6%, 80% dos GIST apresentaram coloração para Bcl-2. O índice proliferativo (expresso como a proporção de células positivas, avaliado pela expressão imunoistoquímica de Ki-67, foi elevado em 49% dos casos. Escores de Ki-67 elevados foram associados com alto grau histológico (p=0,0026 e índice de mitose, MI (p=0,0001. Alto índice de Ki-67 foi associado à morte. Expressão da p53, p16 e Bcl-2 não se correlacionou com as variáveis morfológicas ou clínicas. CONCLUSÕES: A avaliação imunoistoquímica de Ki-67 deve ser incluída na avaliação pré-operatória de biópsias ou peças cirúrgicas de GIST como uma ferramenta prognóstica para o estadiamento clínico, e todas as outras proteínas estudadas (Bcl-2, p53 e p16 não desempenharam um papel no processo metabólico ou carcinogênico em GIST, mantendo-se sem valor prognóstico.

Ricardo Artigiani Neto

2012-05-01

258

Ki-67 expression score correlates to survival rate in gastrointestinal stromal tumors (GIST) / Escore de expressão de Ki-67 correlaciona-se com taxa de sobrevida em tumores estromais gastrointestinais (GIST)  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in portuguese OBJETIVO: Avaliar a expressão imunoistoquímica de p16, Ki-67, p53 e Bcl-2 proteínas em tumores gastrointestinais estromais (GIST); determinar a possível associação entre essas variáveis e fatores clínicos e histopatológicos de câncer, e para verificar o valor prognóstico destas variáveis (sobrevivên [...] cia e recorrência). MÉTODOS: Uma amostra de 55 pacientes tratados cirurgicamente para GIST em três hospitais foi estudada. Os tumores extirpados cirurgicamente foram confirmados como GIST por KIT, vimentina, proteína desmina S100, CD117, 1A4 e avaliação de CD34 em blocos de parafina. RESULTADOS: Apenas nove (16%) casos de GIST foram positivos para p53, p16 foi positiva em 43,6%, 80% dos GIST apresentaram coloração para Bcl-2. O índice proliferativo (expresso como a proporção de células positivas), avaliado pela expressão imunoistoquímica de Ki-67, foi elevado em 49% dos casos. Escores de Ki-67 elevados foram associados com alto grau histológico (p=0,0026) e índice de mitose, MI (p=0,0001). Alto índice de Ki-67 foi associado à morte. Expressão da p53, p16 e Bcl-2 não se correlacionou com as variáveis morfológicas ou clínicas. CONCLUSÕES: A avaliação imunoistoquímica de Ki-67 deve ser incluída na avaliação pré-operatória de biópsias ou peças cirúrgicas de GIST como uma ferramenta prognóstica para o estadiamento clínico, e todas as outras proteínas estudadas (Bcl-2, p53 e p16) não desempenharam um papel no processo metabólico ou carcinogênico em GIST, mantendo-se sem valor prognóstico. Abstract in english PURPOSE: To evaluate the immunohistochemical expression of p16, Ki-67, p53 and Bcl-2 proteins in gastrointestinal stromal tumors (GIST); to assess the possible association between these variables and clinical and histopathological factors of cancer; and to check for prognostic value of these variabl [...] es (survival and recurrence). METHODS: A sample of 55 patients treated surgically for GIST in three hospitals was studied. The surgically excised tumors were confirmed as GIST by KIT, vimentin, desmin S100 protein, CD117, 1A4 and CD34 assessment in paraffin blocks. RESULTS: Only 9 (16%) cases of GIST were positive for p53, p16 was positive among 43.6%; 80% of GISTs showed staining for Bcl-2. The proliferative index (expressed as the proportion of positive cells) assessed by immunohistochemical expression of Ki-67 was high in 49% of cases. Elevated Ki-67 scores were associated to high histological grade (p=0.0026) and mitosis index, MI (p=0.0001). High Ki-67 index was associated to death. Expression of p53, p16 and Bcl-2 did not correlate to morphological or clinical variables. CONCLUSIONS: Ki-67 immunohistochemical evaluation should be included in preoperative evaluation of GIST biopsies or surgical specimens as a prognostic tool for clinical staging; and all other proteins studied (Bcl-2, p53 and p16) did not play a role in GIST metabolic or carcinogenic process, remaining without prognostic value.

Ricardo, Artigiani Neto; Angela Flavia, Logullo; João Norberto, Stávale; Laércio Gomes, Lourenço.

2012-05-01

259

Ki-67 expression score correlates to survival rate in gastrointestinal stromal tumors (GIST) / Escore de expressão de Ki-67 correlaciona-se com taxa de sobrevida em tumores estromais gastrointestinais (GIST)  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in portuguese OBJETIVO: Avaliar a expressão imunoistoquímica de p16, Ki-67, p53 e Bcl-2 proteínas em tumores gastrointestinais estromais (GIST); determinar a possível associação entre essas variáveis e fatores clínicos e histopatológicos de câncer, e para verificar o valor prognóstico destas variáveis (sobrevivên [...] cia e recorrência). MÉTODOS: Uma amostra de 55 pacientes tratados cirurgicamente para GIST em três hospitais foi estudada. Os tumores extirpados cirurgicamente foram confirmados como GIST por KIT, vimentina, proteína desmina S100, CD117, 1A4 e avaliação de CD34 em blocos de parafina. RESULTADOS: Apenas nove (16%) casos de GIST foram positivos para p53, p16 foi positiva em 43,6%, 80% dos GIST apresentaram coloração para Bcl-2. O índice proliferativo (expresso como a proporção de células positivas), avaliado pela expressão imunoistoquímica de Ki-67, foi elevado em 49% dos casos. Escores de Ki-67 elevados foram associados com alto grau histológico (p=0,0026) e índice de mitose, MI (p=0,0001). Alto índice de Ki-67 foi associado à morte. Expressão da p53, p16 e Bcl-2 não se correlacionou com as variáveis morfológicas ou clínicas. CONCLUSÕES: A avaliação imunoistoquímica de Ki-67 deve ser incluída na avaliação pré-operatória de biópsias ou peças cirúrgicas de GIST como uma ferramenta prognóstica para o estadiamento clínico, e todas as outras proteínas estudadas (Bcl-2, p53 e p16) não desempenharam um papel no processo metabólico ou carcinogênico em GIST, mantendo-se sem valor prognóstico. Abstract in english PURPOSE: To evaluate the immunohistochemical expression of p16, Ki-67, p53 and Bcl-2 proteins in gastrointestinal stromal tumors (GIST); to assess the possible association between these variables and clinical and histopathological factors of cancer; and to check for prognostic value of these variabl [...] es (survival and recurrence). METHODS: A sample of 55 patients treated surgically for GIST in three hospitals was studied. The surgically excised tumors were confirmed as GIST by KIT, vimentin, desmin S100 protein, CD117, 1A4 and CD34 assessment in paraffin blocks. RESULTS: Only 9 (16%) cases of GIST were positive for p53, p16 was positive among 43.6%; 80% of GISTs showed staining for Bcl-2. The proliferative index (expressed as the proportion of positive cells) assessed by immunohistochemical expression of Ki-67 was high in 49% of cases. Elevated Ki-67 scores were associated to high histological grade (p=0.0026) and mitosis index, MI (p=0.0001). High Ki-67 index was associated to death. Expression of p53, p16 and Bcl-2 did not correlate to morphological or clinical variables. CONCLUSIONS: Ki-67 immunohistochemical evaluation should be included in preoperative evaluation of GIST biopsies or surgical specimens as a prognostic tool for clinical staging; and all other proteins studied (Bcl-2, p53 and p16) did not play a role in GIST metabolic or carcinogenic process, remaining without prognostic value.

Ricardo, Artigiani Neto; Angela Flavia, Logullo; João Norberto, Stávale; Laércio Gomes, Lourenço.

260

Calculating a Score of Sustainable Development  

Directory of Open Access Journals (Sweden)

Full Text Available Sustainable development is considered to be one of the most important economic issues today. Sustainable development indicators are taken into account when comparing the countries in terms of the level of development. Besides, these indicators are taken to be a major source of information in deciding the development policies the countries will follow as well as for a wide range of investment decisions. In this study, by using sustainable development indicators, we develop scores of sustainable development for the Commonwealth of Indepen-dent States (CIS, the Baltic Republics (BC and Russia in the context of principal components analysis. Subsequently, the sustainable development scores of the investigated countries and the United Nations Human Development Index (HDI scores were compared, and the relationship between the two was evaluated. The correlation coefficient between the two scores was found to be 0.872 and statistically significant at 1 % level.

Fatih ÇEMREK

2013-12-01

 
 
 
 
261

Vouchers and Test Scores.  

Science.gov (United States)

Evaluates a school-choice pilot program in New York City funded by the School Choice Scholarship Foundation. School-choice students in grades four and five achieved substantially higher scores in math and reading. Compares and evaluates school-choice programs in Milwaukee (Wisconsin), San Antonio (Texas), and Cleveland (Ohio) schools. (MMU)

Peterson, Paul E.

1999-01-01

262

[Delirium assessment scoring scales].  

Science.gov (United States)

Delirium is a significant psychiatric disorder in intensive care units that has negative impact on morbidity and mortality of intensive care patients. Subjective clinical assessment of patients by non-psychiatric health professionals in intensive care units is not sufficient for detection and measurement of delirium. Therefore, different scoring scales for delirium assessment have been developed. This paper reviews the characteristics of commonly used scoring scales for assessment of delirium in intensive care units: the Confusion Assessment Method-Intensive Care Unit (CAM-ICU), the Intensive Care Delirium Screening Checklist (ICD-SC), the Nursing Delirium Screening Scale (Nu-DESC) and the Detecting Delirium Scale (DDS). Routine implementation of objective scoring scales is not widespread. Evidence suggests that objective assessment of delirium contributes to its early detection in intensive care and initiation of appropriate treatment. It is therefore advisable to make additional educational effort to provide an objective scoring scale for the assessment of delirium, such as CAM-ICU, to be routinely used in intensive care units. PMID:23088084

Goranovi?, Tatjana; Adam, Visnja Nesek; Tonkovi?, Dinko; Martinac, Miran; Saki?, Kata

2012-03-01

263

score-network.org  

...org 24 February 2014 Michael Graham Marshall Programme Leader, Economics Programmes, UEL contact: Michael Marshall tel: 0208 223 2227 fax: 0208 223 3395 m.g.marshall@uel.ac.uk organization: University of East London , Business School Docklands Campus, University Way , E16 2RD , London , UK score interest / role: I am interested in the role of technology and social innovation ...

264

score-network.org  

...uk organization: University of Ulster School of the Built Environment , Newtownabbey, Co Antrim BT370AG , United Kingdom http://www.ulster.ac.uk biography: Urban planning and sustainable design with emphasis on energy efficiency in mobilily and buildings, Housing economics, property development. score interest / role: Mobility, energy efficiency in travel and buildings in urban areas. ...

265

Fetal Biophysical Profile Scoring  

Directory of Open Access Journals (Sweden)

Full Text Available   "nFetal biophysical profile scoring is a sonographic-based method of fetal assessment first described by Manning and Platt in 1980. "nThe biophysical profile score was developed as a method to integrate real-time observations of the fetus and his/her intrauterine environment in order to more comprehensively assess the fetal condition. These findings must be evaluated in the context of maternal/fetal history (i.e., chronic hypertension, post-dates, intrauterine growth restriction, etc, fetal structural integrity (presence or absence of congenital anomalies, and the functionality of fetal support structures (placental and umbilical cord. For example, acute asphyxia due to placental abruption may result in an absence of the acute variables of the biophysical profile score (fetal breathing movements, fetal movement, fetal tone, and fetal heart rate reactivity with a normal amniotic fluid volume. With post maturity the asphyxial event may be intermittent and chronic resulting in a decrease in amniotic fluid volume, but with the acute variables remaining normal. "nWhile the 5 components of the biophysical profile score have remained unchanged since 1980 (Manning, 1980, the definitions of a normal and abnormal parameter have evolved with increasing experience. "nIn 1984 the definition of oligohydramnios was increased from < 1cm pocket of fluid to < 2.0 x 1.0 cm pocket. Oligohydramnios is now defined as a pocket of amniotic fluid < 2.0 x 2.0 cm (Manning, 1995a "nIf the four ultrasound variables are normal, the accuracy of the biophysical profile score was not found to be significantly improved by adding the non-stress test. As a result, in 1987 the profile score was modified to incorporate the non-stress test only when one of the ultrasound variables was abnormal (Manning 1987. Table 1 outlines the current definitions for quantifying a variable as present or absent. "nEach of the 5 components of the biophysical profile score does not have equal significance. Fetal breathing movements, amniotic fluid volume, and the non-stress test are the most powerful variables. For example, when the biophysical profile score is 2, the perinatal mortality varies between 428/1000 with only fetal movement present to 66/1000 if the non-stress test is reactive and all of the ultrasound parameters are absent (Manning 1990b. Some authors have, therefore, proposed utilization of a modified biophysical profile that incorporates only the non-stress test and amniotic fluid volume (Miller 1996. Although the positive predictive value of these 2 tests is equivalent to a biophysical profile score of 6, the perinatal mortality is still increased over a normal test score of 8 or 10 (Manning 1990b. The false positive rate with the modified biophysical profile score is also substantially higher. "nConclusions: The fetus expresses its well being or compromised status through a number of different biophysical activities that are controlled by different central nervous system centers. The utilization of the biophysical score for antepartum surveillance in high-risk patients has resulted in a reduction in perinatal mortality when compared to historical controls. The appropriate management of the viable fetus with an abnormal biophysical profile score may also decrease long-term neurological morbidity (Manning 1998. "nIt is unlikely that in the future additional variables will be added to the biophysical profile score. However, perhaps the incorporation of the fetal state (i.e., eye movements and Doppler flow studies of specific fetal vessels (umbilical artery, middle cerebral artery, ductus venosus will be incorporated into a complete assessment of the fetal condition "n "nTable 1. Components of the 30 Minute Biophysical Profile Score "nComponent "nDefinition "nFetal movements "n> 3 body or limb movements "nFetal tone "nOne episode of active extension and flexion of the limbs; opening and closing of hand "nFetal breathing movements "n>1

H.R. HaghighatKhah

2009-01-01

266

Correlación entre las buenas prácticas de manufactura y el cumplimiento de los criterios microbiológicos en la fabricación de helados en Chile / Correlation between the good manufacturing practices and compliance with microbiological criteria in the manufacture of ice cream in Chile  

Scientific Electronic Library Online (English)

Full Text Available SciELO Chile | Language: Spanish Abstract in spanish Las Buenas Prácticas de Manufacturas (BPM) son una herramienta básica para obtener un producto alimenticio seguro para consumo humano. El objetivo de este estudio fue determinar el porcentaje de cumplimiento de BPM y su correlación con la aceptación de criterios microbiológicos en fábricas y muestra [...] s de helados de Ñuble, Chile, de acuerdo al Reglamento Sanitario de Alimentos chilenos. Se analizaron auditorías de BPM aplicadas por fiscalizadores de Secretaría Regional Ministerial (SEREMI) de Salud Ñuble, a 40 fábricas de helados y los resultados microbiológicos de 435 muestras de helados entre los años 2005 y 2010. Se determinó que el 55,2% de las muestras no cumplieron para RAM (105 UFC/g) y coliformes (102 UFC/g) y 4,6% para Staphylococcus aureus (102 UFC/g), en cambio el 100% cumplieron para Salmonella spp. Los mayores RAM fueron en verano con 60% de rechazo. El 67% de auditorías de BPM alcanzaron valores superiores al mínimo (70% de cumplimiento), las instalaciones fue el ítem mejor evaluado (88,4%), y capacitación del personal el peor (20,3 %). La correlación entre los resultados de auditorías de BPM y criterios microbiológicos permitió comprobar que con un porcentaje igual o superior al 80% de cumplimiento de BPM se aseguraría la calidad microbiológica de helados, disminuyendo con ello el riesgo en la salud del consumidor. Abstract in english The Good Manufacturing Practices (GMP) is a basic tool to obtain safe foodstuffs for human consumption. The main goal of this research was to determine the percentage of compliance with GMP in ice cream factories and its correlation with the acceptance of microbiological criteria in samples of ice c [...] ream, according to the Sanitary Chilean Food Regulation. Inspectors from the Ministerial Regional Secretariat (SEREMI) of Health Ñuble audited GMP in 40 ice cream factories and 435 microbial analyses from ice cream samples taken between the years 2005 and 2010 were analyzed. Results showed that 55.2% of samples failed in RAM (105 UFC/g) and coliform (102 UFC/g) and 4.6% for Staphylococcus aureus (102 UFC/g) and 100% for Salmonella spp. The biggest RAM was during summer with 60% rejection. Sixty seven% of inspections of GMP reached values above the minimum (70% compliance). Facilities were the best item assessed (88.4%), and training was the worst (20.3%). The correlation between the results of audits of GMP and microbiological criteria allowed proving that with a percentage equal to or greater than 80% compliance with GMP would ensure the microbiological quality of ice cream, thereby decreasing the risk for consumer health.

José Miguel, Bastías M; Marcela, Cuadra H; Ociel, Muñoz F; Roberto, Quevedo L.

2013-06-01

267

Description and validation of a scoring system for tomosynthesis in pulmonary cystic fibrosis  

Energy Technology Data Exchange (ETDEWEB)

To design and validate a scoring system for tomosynthesis (digital tomography) in pulmonary cystic fibrosis. A scoring system dedicated to tomosynthesis in pulmonary cystic fibrosis was designed. Three radiologists independently scored 88 pairs of radiographs and tomosynthesis examinations of the chest in 60 patients with cystic fibrosis and 7 oncology patients. Radiographs were scored according to the Brasfield scoring system and tomosynthesis examinations were scored using the new scoring system. Observer agreements for the tomosynthesis score were almost perfect for the total score with square-weighted kappa >0.90, and generally substantial to almost perfect for subscores. Correlation between the tomosynthesis score and the Brasfield score was good for the three observers (Kendall's rank correlation tau 0.68, 0.77 and 0.78). Tomosynthesis was generally scored higher as a percentage of the maximum score. Observer agreements for the total score for Brasfield score were almost perfect (square-weighted kappa 0.80, 0.81 and 0.85). The tomosynthesis scoring system seems robust and correlates well with the Brasfield score. Compared with radiography, tomosynthesis is more sensitive to cystic fibrosis changes, especially bronchiectasis and mucus plugging, and the new tomosynthesis scoring system offers the possibility of more detailed and accurate scoring of disease severity. (orig.)

Vult von Steyern, Kristina; Bjoerkman-Burtscher, Isabella M.; Bozovic, Gracijela; Wiklund, Marie; Geijer, Mats [Skaane University Hospital, Lund University, Centre for Medical Imaging and Physiology, Lund (Sweden); Hoeglund, Peter [Skaane University Hospital, Competence Centre for Clinical Research, Lund (Sweden)

2012-12-15

268

Description and validation of a scoring system for tomosynthesis in pulmonary cystic fibrosis  

International Nuclear Information System (INIS)

To design and validate a scoring system for tomosynthesis (digital tomography) in pulmonary cystic fibrosis. A scoring system dedicated to tomosynthesis in pulmonary cystic fibrosis was designed. Three radiologists independently scored 88 pairs of radiographs and tomosynthesis examinations of the chest in 60 patients with cystic fibrosis and 7 oncology patients. Radiographs were scored according to the Brasfield scoring system and tomosynthesis examinations were scored using the new scoring system. Observer agreements for the tomosynthesis score were almost perfect for the total score with square-weighted kappa >0.90, and generally substantial to almost perfect for subscores. Correlation between the tomosynthesis score and the Brasfield score was good for the three observers (Kendall's rank correlation tau 0.68, 0.77 and 0.78). Tomosynthesis was generally scored higher as a percentage of the maximum score. Observer agreements for the total score for Brasfield score were almost perfect (square-weighted kappa 0.80, 0.81 and 0.85). The tomosynthesis scoring system seems robust and correlates well with the Brasfield score. Compared with radiography, tomosynthesis is more sensitive to cystic fibrosis changes, especially bronchiectasis and mucus plugging, and the new tomosynthesis scoring system offers the possibility of more detailed and accurate scoring of disease severity. (orig.)

269

Pronuclear scoring as a predictor of embryo quality in in vitro fertilization program.  

Directory of Open Access Journals (Sweden)

Full Text Available Many strategies have been proposed for the selection of viable embryos for transfer in human assisted reproduction. These have included morphological scoring criteria for 20, 28, 44 and 68 h after insemination. The embryo selection is based on morphology, degree of fragmentation and development to the 8-cell. All have shown some correlation with implantation. However, the overall success of these methods is still limited, with over 50% of all transferred embryos failing to implant. Pronuclear zygote morphology has gained much attention recently due to its positive value in predicting implantation and pregnancy. This prospective study involved 178 conventional IVF patients only. The key aspects of pronuclear scoring and namely the presence of a cytoplasmic halo were related to day 3 of development and morphology in a retrospective study. The Z-score and the presence/absence of a halo had significant effect on the rate of development on day 3 embryo. Low Z-score result in slow development and poor morphology. The absence of a halo also resulted in slow and poor development, low morphology, increased fragmentation.

Leszek Pawelczyk

2008-04-01

270

The Relationship between Odour Annoyance Scores and Modelled Ambient Air Pollution in Sarnia, “Chemical Valley”, Ontario  

Directory of Open Access Journals (Sweden)

Full Text Available This study aimed at establishing the relationship between annoyance scores and modelled air pollution in “Chemical Valley”, Sarnia, Ontario (Canada. Annoyance scores were taken from a community health survey (N = 774; and respondents’ exposure to nitrogen dioxide (NO2 and sulphur dioxide (SO2 were estimated using land use regression (LUR models. The associations were examined by univariate analysis while multivariate logistic regression was used to examine the determinants of odour annoyance. The results showed that odour annoyance was significantly correlated to modelled pollutants at the individual (NO2, r = 0.15; SO2, r = 0.13 and census tract (NO2, r = 0.56; SO2, r = 0.67 levels. The exposure-response relationships show that residents of Sarnia react to very low pollution concentrations levels even if they are within the Ontario ambient air quality criteria. The study found that exposure to high NO2 and SO2 concentrations, gender, and perception of health effects were significant determinants of individual odour annoyance reporting. The observed association between odour annoyance and modelled ambient pollution suggest that individual and census tract level annoyance scores may serve as proxies for air quality in exposed communities because they capture the within area spatial variability of pollution. However, questionnaire-based odour annoyance scores need to be validated longitudinally and across different scales if they are to be adopted for use at the national level.

Dominic Odwa Atari

2009-10-01

271

Application of a new immunohistology scoring system (IH score): Analysis of TNF-? in synovium related to disease activity score in infliximab-treated patients with rheumatoid arthritis.  

Science.gov (United States)

Abstract Objectives. This study aimed to analyze the relationship between the expression of tumor necrosis factor alpha (TNF-?) or interleukin-6 (IL-6) in synovium and the disease activity score (DAS) 28 (C-reactive protein, CRP) in treatment of infliximab for rheumatoid arthritis (RA). Methods. Synovial tissues were obtained from 16 infliximab-treated patients and assessed for TNF-? and IL-6 with a new immunohistology (IH) scoring system. The validation of IH score was performed and applied for the analysis of correlation between synovial TNF-? or IL-6 and DAS28 (CRP) in addition to Rooney score. Results. The IH score had high internal validity; the IH score of TNF-? strongly correlated with serum CRP and matrix metalloprotease-3 (MMP-3), as well as DAS28 (CRP) and the Rooney score. IL-6 did not correlate with DAS28 (CRP). Conclusions. This study indicates that the IH score is useful as a new procedure to assess the cytokine expression easily and TNF-? in synovium correlates with disease activity in patients with RA treated with infliximab. PMID:24670132

Kanbe, Katsuaki; Hara, Ryota; Chiba, Junji; Inoue, Yasuo; Taguchi, Masashi; Tanaka, Yasuhito

2014-11-01

272

Developing Scoring Algorithms  

Science.gov (United States)

We developed scoring procedures to convert screener responses to estimates of individual dietary intake for fruits and vegetables (cup equivalents), dairy (cup equivalents), added sugars (tsp), whole grains (ounce equivalents), fiber (g), and calcium (mg) using the What We Eat in America 24-hour dietary recall data from the 2003-2006 NHANES. The following equations were estimated in the NHANES 2003-2006, using SAS PROC REG.

273

Criterios ecográficos diagnósticos de neoplasia maligna en el nódulo tiroideo: correlación con la punción por aspiración con aguja fina y la anatomía patológica / Ultrasound diagnostic criteria of malignancy in a thyroid nodule: correlation with fine needle aspiration and pathology  

Scientific Electronic Library Online (English)

Full Text Available SciELO Colombia | Language: Spanish Abstract in spanish Introducción. La ecografía de tiroides ha mejorado la certeza diagnóstica para neoplasia maligna del nódulo tiroideo. Es importante definir qué nódulos requieren biopsia por aspiración con aguja fina (BACAF) para disminuir el costo de un procedimiento innecesario y evitar que pase inadvertido el dia [...] gnóstico de neoplasia maligna. Objetivo. Validar los criterios ecográficos de neoplasia maligna que indican la punción por aspiración con aguja fina de tiroides. Materiales y métodos. Se diseñó un estudio prospectivo a tres años para evaluar la concordancia entre los hallazgos ecográficos y la punción por aspiración con aguja fina de tiroides comparada con el estudio final de histopatología. Se evaluó la sensibilidad, la especificidad, el valor diagnóstico positivo y negativo, la concordancia medida por el coeficiente kappa y el coeficiente de correlación. Resultados. Se estudiaron 1.467 pacientes, 10,2 % hombres y 89,8 % mujeres, con edades entre los 10 y los 95 años; el tamaño promedio del nódulo fue de 16 mm. Un total de 623 requirieron tiroidectomía; al resto se les hizo seguimiento por ecografía. Se presentaron 269 carcinomas papilares, 14 foliculares, 4 indiferenciados, 159 bocios, 74 adenomas y 101 tiroiditis. Se obtuvo sensibilidad de 86,4 %, especificidad de 89,4 %, valor diagnóstico de un resultado positivo de 87,5 % y uno negativo de 84,1 %. Los hallazgos ecográficos relacionados con cáncer fueron: hipoecogenicidad, microcalcificaciones, papilas y flujo intranodular. Individualmente, la concordancia fue baja, pero con la combinación de hipoecogenicidad, microcalcificaciones y papilas fue media y, con la adición de aumento del flujo intranodular, resultó alta. Conclusiones. La combinación de hipoecogenicidad, microcalcificaciones, papilas y alto flujo intranodular tiene alta concordancia con neoplasia maligna; sin embargo, cada criterio por separado no la tiene, y no pueden usarse individualmente para predecir o descartar neoplasia maligna. Abstract in english Introduction. Thyroid ultrasound has improved the diagnostic accuracy in the diagnosis of malignant neoplasia in thyroid nodules. It is important to define which nodules require fine needle aspiration so as to diminish the costs of unnecessary procedures and at the same time avoid unnoticed malignan [...] cy. Objective. To validate the echographic criteria of malignant neoplasia that validate fine needle aspiration of the thyroid nodule. Material and methods. Three-year prospective study to assess correlation between the ultrasound findings and fine needle aspiration with pathology findings, including sensibility, specificity, positive predictive value, negative predictive value, and concordance measured by Kappa coefficient, and correlation coefficient. Results. The study included 1,467 patients, 10,2% males and 89,8% females, with ages ranging from 10 years to 95 years; average size of the nodule was 16 mm; 623 patients required thyroidectomy, while the remainder were followed by ultrasound. There were 269 papillary carcinomas, 14 follicular carcinomas, 4 anaplastic carcinomas, 159 goiters, 74 adenomas, and 101 thyroiditis. Sensibility was 86,4%, specificity was 89,4%, positive predictive value 87,5%, and negative predictive value 84,1%. Ultrasound findings related with cancer were hypoechogenicity, microcalcifications, papillae, and intranodal flow; when adding intranodal flow, concordance was high. Conclusions. The combination of hypoechogenicity, microcalcifications, papillae and high intranodal flow exhibit high concordance with malignancy; however, echographic criteria considered individually does not, and those individual criteria cannot be used to predict or rule out malignant neoplasia.

Andrés Ignacio, Chala; Rafael, Pava; Humberto Ignacio, Franco; Andrés, Álvarez; Armando, Franco.

2013-03-01

274

Criterios ecográficos diagnósticos de neoplasia maligna en el nódulo tiroideo: correlación con la punción por aspiración con aguja fina y la anatomía patológica Ultrasound diagnostic criteria of malignancy in a thyroid nodule: correlation with fine needle aspiration and pathology  

Directory of Open Access Journals (Sweden)

Full Text Available Introducción. La ecografía de tiroides ha mejorado la certeza diagnóstica para neoplasia maligna del nódulo tiroideo. Es importante definir qué nódulos requieren biopsia por aspiración con aguja fina (BACAF para disminuir el costo de un procedimiento innecesario y evitar que pase inadvertido el diagnóstico de neoplasia maligna. Objetivo. Validar los criterios ecográficos de neoplasia maligna que indican la punción por aspiración con aguja fina de tiroides. Materiales y métodos. Se diseñó un estudio prospectivo a tres años para evaluar la concordancia entre los hallazgos ecográficos y la punción por aspiración con aguja fina de tiroides comparada con el estudio final de histopatología. Se evaluó la sensibilidad, la especificidad, el valor diagnóstico positivo y negativo, la concordancia medida por el coeficiente kappa y el coeficiente de correlación. Resultados. Se estudiaron 1.467 pacientes, 10,2 % hombres y 89,8 % mujeres, con edades entre los 10 y los 95 años; el tamaño promedio del nódulo fue de 16 mm. Un total de 623 requirieron tiroidectomía; al resto se les hizo seguimiento por ecografía. Se presentaron 269 carcinomas papilares, 14 foliculares, 4 indiferenciados, 159 bocios, 74 adenomas y 101 tiroiditis. Se obtuvo sensibilidad de 86,4 %, especificidad de 89,4 %, valor diagnóstico de un resultado positivo de 87,5 % y uno negativo de 84,1 %. Los hallazgos ecográficos relacionados con cáncer fueron: hipoecogenicidad, microcalcificaciones, papilas y flujo intranodular. Individualmente, la concordancia fue baja, pero con la combinación de hipoecogenicidad, microcalcificaciones y papilas fue media y, con la adición de aumento del flujo intranodular, resultó alta. Conclusiones. La combinación de hipoecogenicidad, microcalcificaciones, papilas y alto flujo intranodular tiene alta concordancia con neoplasia maligna; sin embargo, cada criterio por separado no la tiene, y no pueden usarse individualmente para predecir o descartar neoplasia maligna.Introduction. Thyroid ultrasound has improved the diagnostic accuracy in the diagnosis of malignant neoplasia in thyroid nodules. It is important to define which nodules require fine needle aspiration so as to diminish the costs of unnecessary procedures and at the same time avoid unnoticed malignancy. Objective. To validate the echographic criteria of malignant neoplasia that validate fine needle aspiration of the thyroid nodule. Material and methods. Three-year prospective study to assess correlation between the ultrasound findings and fine needle aspiration with pathology findings, including sensibility, specificity, positive predictive value, negative predictive value, and concordance measured by Kappa coefficient, and correlation coefficient. Results. The study included 1,467 patients, 10,2% males and 89,8% females, with ages ranging from 10 years to 95 years; average size of the nodule was 16 mm; 623 patients required thyroidectomy, while the remainder were followed by ultrasound. There were 269 papillary carcinomas, 14 follicular carcinomas, 4 anaplastic carcinomas, 159 goiters, 74 adenomas, and 101 thyroiditis. Sensibility was 86,4%, specificity was 89,4%, positive predictive value 87,5%, and negative predictive value 84,1%. Ultrasound findings related with cancer were hypoechogenicity, microcalcifications, papillae, and intranodal flow; when adding intranodal flow, concordance was high. Conclusions. The combination of hypoechogenicity, microcalcifications, papillae and high intranodal flow exhibit high concordance with malignancy; however, echographic criteria considered individually does not, and those individual criteria cannot be used to predict or rule out malignant neoplasia.

Andrés Ignacio Chala

2013-03-01

275

Credit scoring for individuals  

Directory of Open Access Journals (Sweden)

Full Text Available Lending money to different borrowers is profitable, but risky. The profits come from the interest rate and the fees earned on the loans. Banks do not want to make loans to borrowers who cannot repay them. Even if the banks do not intend to make bad loans, over time, some of them can become bad. For instance, as a result of the recent financial crisis, the capability of many borrowers to repay their loans were affected, many of them being on default. That’s why is important for the bank to monitor the loans. The purpose of this paper is to focus on credit scoring main issues. As a consequence of this, we presented in this paper the scoring model of an important Romanian Bank. Based on this credit scoring model and taking into account the last lending requirements of the National Bank of Romania, we developed an assessment tool, in Excel, for retail loans which is presented in the case study.

Maria DIMITRIU

2010-12-01

276

Fat scoring: Sources of variability  

Science.gov (United States)

Fat scoring is a widely used nondestructive method of assessing total body fat in birds. This method has not been rigorously investigated. We investigated inter- and intraobserver variability in scoring as well as the predictive ability of fat scoring using five species of passerines. Between-observer variation in scoring was variable and great at times. Observers did not consistently score species higher or lower relative to other observers nor did they always score birds with more total body fat higher. We found that within-observer variation was acceptable but was dependent on the species being scored. The precision of fat scoring was species-specific and for most species, fat scores accounted for less than 50% of the variation in true total body fat. Overall, we would describe fat scoring as a fairly precise method of indexing total body fat but with limited reliability among observers.

Krementz, D.G.; Pendleton, G.W.

1990-01-01

277

Application and evaluation of scoring system for priority air pollutants  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Voor een geselecteerd aantal milieuhygienische criteria, aansluitend bij het WMS-scoringssysteem (Wet Milieugevaarlijke Stoffen), zijn door deskundigen scores bepaald voor een 400-tal uit de Emissieregistratie komende stoffen. Na een geautomatiseerde verwerking van deze scores, door het RIVM, tot gecombineerde effect- en expositiescores, is een eerste selectie gemaakt van een 50-tal stoffen door het DGMH, die mogelijk in aanmerking zouden kunnen komen voor aanvulling v...

Balfoort; F. (M.Sc); Spierenburg; R.E.*; Swart; R.J.

2012-01-01

278

7 CFR 3406.15 - Evaluation criteria for teaching proposals.  

Science.gov (United States)

...Review and Evaluation of a Teaching Proposal § 3406.15 Evaluation criteria for teaching proposals. The maximum score a teaching proposal can receive is...Federal Register, the peer review panel will consider...

2010-01-01

279

Validity and predictive ability of the juvenile arthritis disease activity score based on CRP versus ESR in a Nordic population-based setting  

DEFF Research Database (Denmark)

OBJECTIVE: To compare the juvenile arthritis disease activity score (JADAS) based on C reactive protein (CRP) (JADAS-CRP) with JADAS based on erythrocyte sedimentation rate (ESR) (JADAS-ESR) and to validate JADAS in a population-based setting.METHODS: The CRP and ESR values and the corresponding JADAS scores (JADAS10/27/71) were compared in a longitudinal cohort study of 389 children newly diagnosed with juvenile idiopathic arthritis (JIA) in the Nordic JIA study. The construct validity and the discriminative and predictive ability of JADAS were assessed during a median disease course of 8 years by comparing JADAS with other measures of disease activity and outcome.RESULTS: At the first study visit the correlation between JADAS27-CRP and JADAS27-ESR was r=0.99 whereas the correlation between CRP and ESR was r=0.57. Children with higher JADAS scores had an increased risk of concomitant pain, physical disability and use of disease-modifying antirheumatic drugs (DMARDs). A higher JADAS score at the first study visit also significantly predicted physical disability, damage and no remission off medication at the final study visit, and also use of DMARDs during the disease course. Sensitivity to change, demonstrated as change in JADAS score compared with the American College of Rheumatology paediatric measures of improvement criteria, mostly showed excellent classification ability.CONCLUSION: The JADAS-CRP and JADAS-ESR correlate closely, show similar test characteristics and are feasible and valid tools for assessing disease activity in JIA.

Nordal, E B; Zak, Marek Stanislaw

2012-01-01

280

Criteria for nonoperative management of blunt splenic trauma  

Directory of Open Access Journals (Sweden)

Full Text Available "nBackground: Although nonoperative management is as an alternative method for surgery in the management of blunt splenic trauma, there are many contraversies in criteria for appropriate selection of the best method of management in patients. This study was conducted to find clinical and diagnostic criteria for selection of patients for surgery. "nMethods: One hundred and one patients with blunt splenic injury entered in our prospective observational and cross sectional study. Patients with unstable hemodyna-mics and obvious abdominal symptoms underwent emergency splenectomy was performed. In stable patients, abdominal and pelvic CT scan with IV contrast was performed. Patients with stable hemodynamics who lack obvious abdominal symptoms, admitted in ICU ward. Patients' demographics, blood pressure changes, hemoglobin concertration, severity of trauma with injury severity score (ISS scoring system, CT scan findings, amount of blood transfusion; Hospitalization time and mechanism of injury were recorded. "nResults: From 101 patients, 61(60.3% underwent early laparotomy. 40 patients were planned for conservative management. In 30 patients (29.7% nonoperative management was successful. In 10 patients (9.9% This management failed and they underwent surgery. Hypotension, hemoglobin concentration dropping more than one episode and blood transfusion requirement more than one time, increased the risk of operation. Higher ISS number and ISS?16 had a direct relation with operative management. In patients who underwent early laparotomy CT grade of injury was higher. CT findings correlated well with laparotomy findings. "nConclusion: Nonoperative management was successful in 75% of selected patients. With correct selection of patients and concerning to homodynamic status, hemoglobin concentration changes and injury severity score in conjunction with CT findings, we can use this management in greater number of patients.

Sarmast Shoushtary MH

2009-02-01

 
 
 
 
281

score-network.org  

...tr/ biography: He is contributor and lecturer of “Responsible Care” Certificate Training Program of KMO (Turkish Chambers of Chemical Engineers) for the engineers of the industry and author of relevant certificate training modules on “Environmental Pollution and Control” and “Environmental Impact Assessment”. He is “Energy and Natural Resources” Panel Member of the Vision 2023 Foresight Project of Turkish Scientific and Technical Research Council (TÜBITAK). He participated ... He is Member of the DECHEMA/Frankfurt, TUNCAP (Turkish National Committee for Air Pollution Control) and KMO ( Turkish Chamber of Chemical Engineers). score interest / role: Collaboration possibilities within FP7 Calls and MS Programs on Sustainable Development biography (pdf 499K) ...

282

score-network.org  

...uk organization: Nottingham Trent University Burton Street , Nottingham , UK biography: From a background in Design and Fine Art, Tom Fisher`s research interests are in human/ object relationships in a range of settings from the materiality of everyday objects to the immateriality of musical performance. His research has concentrated on the role that materials play in everyday experiences with objects and this has informed work on the reuse of packaging (... score interest / role: Tom Fisher`s interest in sustainable consumption centres on the intersection of cultural values, social relationships and materiality in everyday routines. Opportunities to change routines and to modify their environmental impact can only derive from understanding such interesections. ...

283

Association between scores in high school, aptitude and achievement exams and early performance in health science college  

Directory of Open Access Journals (Sweden)

Full Text Available This retrospective study was carried out to assess the correlation between admi-ssion criteria to health science colleges, namely, final high school grade and Saudi National Apti-tude and Achievement exams, and early academic performance in these colleges. The study inclu-ded 91 male students studying in the two-year pre-professional program at the King Saud bin Abdulaziz University for Health Sciences (KSAU-HS, Riyadh, Saudi Arabia. Records of these students were used to extract relevant information and their academic performance (based on the grade point average achieved at the end of the first semester of the pre-professional program, which were analytically studied. Pearson correlation coefficient was used to assess the associa-tions between the different scores. SPSS statistical program (version 12.0 was used for data ana-lyses. We found a strong correlation between the academic performance and the Achievement Exam, Aptitude Exam and high school final grade, with Pearson Correlation Coefficients of 0.96, 0.93, 0.87, respectively. The Saudi National Achievement Exam showed the most significant correla-tion. Our results indicate that academic performance showed good correlation with the admission criteria used, namely final high school grade, Saudi National Aptitude and Achievement Exams.

Al-Alwan Ibrahim

2009-01-01

284

Association between scores in high school, aptitude and achievement exams and early performance in health science college.  

Science.gov (United States)

This retrospective study was carried out to assess the correlation between admission criteria to health science colleges, namely, final high school grade and Saudi National Aptitude and Achievement exams, and early academic performance in these colleges. The study included 91 male students studying in the two-year pre-professional program at the King Saud bin Abdulaziz University for Health Sciences (KSAU-HS), Riyadh, Saudi Arabia. Records of these students were used to extract relevant information and their academic performance (based on the grade point average achieved at the end of the first semester of the pre-professional program), which were analytically studied. Pearson correlation coefficient was used to assess the associations between the different scores. SPSS statistical program (version 12.0) was used for data analyses. We found a strong correlation between the academic performance and the Achievement Exam, Aptitude Exam and high school final grade, with Pearson Correlation Coefficients of 0.96, 0.93, 0.87, respectively. The Saudi National Achievement Exam showed the most significant correlation. Our results indicate that academic performance showed good correlation with the admission criteria used, namely final high school grade, Saudi National Aptitude and Achievement Exams. PMID:19414949

Al-Alwan, Ibrahim A

2009-05-01

285

SCORE: A Score-Based Memory Cache Replacement Policy  

Digital Repository Infrastructure Vision for European Research (DRIVER)

We propose SCORE, a novel adaptive cache replacement policy, which uses a score system to select a cache line to replace. Results show that SCORE o®ers low over-all miss rates on SPEC CPU2006 benchmarks, and provides an average IPC that is 4.9% higher than LRU and 7.4% higher than LIP.

Duong, Nam; Cammarota, Rosario; Zhao, Dali; Kim, Taesu; Veidenbaum, Alex

2010-01-01

286

Preadmission Criteria as Predictors of Academic Success in Entry-Level Athletic Training and Other Allied Health Educational Programs.  

Science.gov (United States)

OBJECTIVE: To investigate preadmission criteria, Scholastic Aptitude Test (SAT) scores, and high school grade point average (HSGPA) and to determine the ability of those criteria to predict the college grade point average (CGPA) of graduates from programs in athletic training and 5 other allied health disciplines. DESIGN AND SETTING: Descriptive data, including age, sex, year of graduation, HSGPA, CGPA, and SAT scores (SAT mathematics [SATM], SAT verbal [SATV], and SAT total) were gathered from the files of graduates (1992 to 1997) of allied health education programs. SUBJECTS: The complete records of 373 graduates (244 women and 129 men) of 6 allied health education programs in athletic training, health management systems, occupational therapy, perfusion technology, physician assistant, and physical therapy were used in this study. Subjects with incomplete files were excluded from this study. MEASUREMENTS: We collected data from official college transcripts, official high school transcripts, and SAT scores reported to the university. Descriptive statistics, analysis of variance, Pearson correlation, and stepwise forward regression analyses were used to determine the ability of SATV score, SATM score, and HSGPA to predict CGPA. RESULTS: Both SATV score and HSGPA were found to predict 14% of the variance in student success (CGPA) in all allied health programs; however, only HSGPA was predictive of student success in athletic training (P =.00). Both SATV score and HSGPA were predictive of CGPA in both physical (P =.02 and.03, respectively) and occupational (P =.02 and.00, respectively) therapy graduates; however, they predicted only 12% and 21%, respectively, of the variance in CGPA. The SATM score was predictive of CGPA in both perfusion technology (P =.05) and physician assistant (P =.00) graduates, accounting for 7% and 18% of the variance in outcomes. CONCLUSIONS: Overall, HSGPA and SATV score were predictive of student success (CGPA) in the allied health group as a whole and should continue to be used as part of the process of admission in higher education until such time that more predictive criteria are determined. The HSGPA was predictive of CGPA (r(2) = 0.38) in athletic training graduates, predicting more than one third of the professional program success. Athletic training educators should continue to use HSGPA as a predictor of success; however, they may wish to establish similar baseline comparisons between athletic training and other disciplines at their schools before determining the importance of standardized preadmission criteria for future students. This work should be considered a pilot study for the profession of athletic training and should be repeated at individual schools to determine the findings' applicability to other athletic training education programs. PMID:12937454

Platt, Linda S.; Turocy, Paula Sammarone; McGlumphy, Barry E.

2001-06-01

287

Ultrasonography-guided percutaneous radiofrequency ablation of hepatocellular carcinomas: A feasibility scoring system for planning sonography  

Energy Technology Data Exchange (ETDEWEB)

Purpose: This study was designed to evaluate whether a feasibility scoring system for planning sonography is a reliable predictor of a safe and complete ablation in ultrasonography (US)-guided percutaneous radiofrequency ablation (RFA) of hepatocellular carcinomas (HCCs). Materials and methods: We retrospectively evaluated the therapeutic outcomes of 108 consecutive patients (M:F, 78:30; mean age, 57.4 years) with a single nodular HCC (mean diameter, 2.0 cm) treated by percutaneous RFA. All patients were assessed for the feasibility of performing an RFA at planning sonography prior to the ablation. The feasibility scoring system consisted of five categories: the safe electrode path (P); the vital organs adjacent to the RFA zone (O); tumor size (S); tumor conspicuity (C); and the heat-sink effect (H). Each category was divided into a four-point scale [1-4]. If a score of 4 in any category was determined, the patient was not considered to be a suitable candidate for percutaneous RFA. We assessed if the score of each category, safety score (P + O), and curability score (S + C + H) correlated with a safe and complete ablation using the chi-squared test and likelihood ratio test for trend. Results: The technical success rate was 100% (108/108) based on CT images obtained immediately after ablation. There was no 30-day mortality after RFA. There were major complications (one case of severe vasovagal reflex, one case of hemoperitoneum and one case of a pseudoaneurysm) in three (2.7%) patients, and minor complications (one case of a biloma, one case of subsegmental infarction and one case of abscess) in three (2.7%) patients. Post-ablation syndrome as a side effect was noted in 38 (35.1%) of 108 patients. The primary technique effectiveness rate at 1 month was 95.1% (105/108). Local tumor progression was noted in eight (7.6%) of 105 patients during the follow-up period (range, 3.0-11.5 months; median, 5.8 months; mean, 5.7 months). There was no significant single category to predict complication and local tumor progression (Fisher's exact test, p > 0.05). Contrary to the safety score for the probability of complication (p > 0.05), the curability score was significantly associated with the probability of local tumor progression (likelihood ratio test for trend; p = 0.03). Conclusion: The new feasibility scoring system for planning US can be used as objective criteria to predict therapeutic efficacy rather than the safety of percutaneous RFA of an HCC.

Rhim, Hyunchul, E-mail: rhimhc@skku.ed [Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of); Choi, Dongil; Kim, Young-sun; Lim, Hyo K. [Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of); Choe, Bong-Keun [Department of Preventive Medicine, Kyung Hee University School of Medicine, Seoul (Korea, Republic of)

2010-08-15

288

Ultrasonography-guided percutaneous radiofrequency ablation of hepatocellular carcinomas: A feasibility scoring system for planning sonography  

International Nuclear Information System (INIS)

Purpose: This study was designed to evaluate whether a feasibility scoring system for planning sonography is a reliable predictor of a safe and complete ablation in ultrasonography (US)-guided percutaneous radiofrequency ablation (RFA) of hepatocellular carcinomas (HCCs). Materials and methods: We retrospectively evaluated the therapeutic outcomes of 108 consecutive patients (M:F, 78:30; mean age, 57.4 years) with a single nodular HCC (mean diameter, 2.0 cm) treated by percutaneous RFA. All patients were assessed for the feasibility of performing an RFA at planning sonography prior to the ablation. The feasibility scoring system consisted of five categories: the safe electrode path (P); the vital organs adjacent to the RFA zone (O); tumor size (S); tumor conspicuity (C); and the heat-sink effect (H). Each category was divided into a four-point scale [1-4]. If a score of 4 in any category was determined, the patient was not considered to be a suitable candidate for percutaneous RFA. We assessed if the score of each category, safety score (P + O), and curability score (S + C + H) correlated with a safe and complete ablation using the chi-squared test and likelihood ratio test for trend. Results: The technical success rate was 100% (108/108) based on CT images obtained immediately after ablation. There was no 30-day mortality after RFA. There were major complications (one case of severe vasovagal reflex, one case of hemoperitoneum and one case of a pseudoaneurysm) in three (2.7%) patients, and minor complications (one case of a biloma, one case of subsegmental infarction and one case of abscess) in three (2.7%) patients. Post-ablation syndrome as a side effect was noted in 38 (35.1%) of 108 patients. The primary technique effectiveness rate at 1 month was 95.1% (105/108). Local tumor progression was noted in eight (7.6%) of 105 patients during the follow-up period (range, 3.0-11.5 months; median, 5.8 months; mean, 5.7 months). There was no significant single category to predict complication and local tumor progression (Fisher's exact test, p > 0.05). Contrary to the safety score for the probability of complication (p > 0.05), the curability score was significantly associated with the probability of local tumor progression (likelihood ratio test for trend; p = 0.03). Conclusion: The new feasibility scoring system for planning US can be used as objective criteria to predict therapeutic efficacy rather than the safety of percutaneous RFA of an HCC.

289

On the correlation between continuum mechanics entities and cell activity in biological soft tissues: assessment of three possible criteria for cell-controlled fibre reorientation in collagen gels and collagenous tissues.  

Science.gov (United States)

The biomechanical behaviour of biological cells is of great importance in many physiological processes. One such process is the maintenance of fibrous networks, such as collagenous tissues. The activity of the fibre-producing cells in this type of tissue is very important, and a comprehensive material description needs to incorporate the activity of the cells. In biomechanics, continuum mechanics is often employed to describe deforming solids, and modelling can be much simplified if continuum mechanics entities, such as stress and strain, can be correlated with cell activity. To investigate this, a continuum mechanics framework is employed in which remodelling of a collagen gel is modelled. The remodelling is accomplished by fibroblasts, and the activity of the fibroblasts is linked to the continuum mechanics theory. The constitutive model for the collagen fabric is formulated in terms of a strain energy function, which includes a density function describing the distribution of the collagen fibre orientation. This density function evolves according to an evolution law, where fibroblasts reorient fibres towards the direction of increasing Cauchy stress, elastic deformation, or stiffness. The theoretical framework is applied to experimental results from collagen gels, where gels have undergone remodelling under both biaxial and uniaxial constraint. The analyses indicated that criteria 1 and 2 (Cauchy stress and elastic deformations) are able to predict the collagen fibre distribution after remodelling, whereas criterion 3 (current stiffness) is not. This conclusion is, however, tentative and pertains, strictly speaking, only to fibre remodelling processes, and may not be valid for other types of cell activities. PMID:20045702

Kroon, Martin

2010-05-01

290

National Board Scores versus Student GPA's in Chiropractic Education.  

Science.gov (United States)

The relationship between student GPAs and scores on the National Board of Chiropractic Examiners tests was investigated in an effort to determine if the chiropractic curriculum was properly preparing students to be licensed. The study found that there was a significant correlation between GPAs and board scores. (Author/MLW)

Kalthoff, Theodore J.

1985-01-01

291

Longitudinal Factor Score Estimation Using the Kalman Filter.  

Science.gov (United States)

How longitudinal factor score estimation--the estimation of the evolution of factor scores for individual examinees over time--can profit from the Kalman filter technique is described. The Kalman estimates change more cautiously over time, have lower estimation error variances, and reproduce the LISREL program latent state correlations more…

Oud, Johan H.; And Others

1990-01-01

292

Scoring and Analyzing Confidence Tests.  

Science.gov (United States)

This paper examines confidence testing, and reasons for using confidence tests. Different scoring systems are studied in order to clarify the meaning of significance of the weights which subjects assign to confidence scored tests. (DLG)

Rippey, Robert M.

293

An Analysis of Cross Racial Identity Scale Scores Using Classical Test Theory and Rasch Item Response Models  

Science.gov (United States)

Item response models (IRMs) were used to analyze Cross Racial Identity Scale (CRIS) scores. Rasch analysis scores were compared with classical test theory (CTT) scores. The partial credit model demonstrated a high goodness of fit and correlations between Rasch and CTT scores ranged from 0.91 to 0.99. CRIS scores are supported by both methods.…

Sussman, Joshua; Beaujean, A. Alexander; Worrell, Frank C.; Watson, Stevie

2013-01-01

294

Local Observed-Score Equating with Anchor-Test Designs  

Science.gov (United States)

For traditional methods of observed-score equating with anchor-test designs, such as chain and poststratification equating, it is difficult to satisfy the criteria of equity and population invariance. Their equatings are therefore likely to be biased. The bias in these methods was evaluated against a simple local equating method in which the…

van der Linden, Wim J.; Wiberg, Marie

2010-01-01

295

Predicting executive function task scores with the Rey-Osterrieth Complex Figure.  

Science.gov (United States)

The Boston Qualitative Scoring System (BQSS) is one of the scoring methods of the Rey-Osterrieth Complex Figure Test (ROCF). With BQSS, 17 qualitative ratings are generated, and subsequently 6 summary scores are calculated by combining several qualitative scores. Previously we showed that 5 of 6 BQSS summary scores were correlated with the scores of the several executive function tests in children. The objective of this study was to develop a new summary score which correlates with the executive function test scores more strongly than the existing summary scores. For this purpose, we conducted multiple regression analysis to predict PEN, CA, DSM of the Wisconsin Card Sorting Test Keio Version, and the Mazes scores from WISC-III, by the BQSS qualitative scores derived from ROCF drawings in copy condition. The subjects were 78 children with various neuropsychological disorders (5 years 5 months-14 years 11 months; mean: 9 years 2 months; F 22, M 56). Significant predictive models were generated for PEN, CA, and Mazes scores. Among them the models for the Mazes scores were the most accurate. The second model for the Mazes scores was most suitable for a new summary score. Its degree-of-freedom-adjusted coefficient of multiple determination and multiple correlation coefficient reached 0.467 and 0.695, respectively. A new summary score should be applied in future studies to evaluate its clinical usefulness. PMID:18723303

Ogino, Tatsuya; Watanabe, Kiyoko; Nakano, Kousuke; Kado, Yoko; Morooka, Teruko; Takeuchi, Akihito; Oka, Makio; Sanada, Satoshi; Ohtuska, Yoko

2009-01-01

296

NHGP Criteria May 2011  

...Score • Projects that deliver essential management of designated site selection features...High Score • Sharing skills and knowledge to further goals for protecting...there is a gap in knowledge. • Educational activities and national campaigns...

297

Optical syntactic pattern recognition by fuzzy scoring  

International Nuclear Information System (INIS)

A novel syntactic approach is introduced to treat particular problems in pattern recognition. The procedure is implemented by the use of optical correlation methods for identifying the various primitives that appear in the input pattern, and their importance is determined by fuzzy relational scoring. Robust pattern recognition with tolerance to normal variations is demonstrated, indicating an efficient new approach for optical pattern recognition. copyright 1996 Optical Society of America

298

Pediatric appendicitis score: A retrospective analysis  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Aims: Evaluation of the pediatric appendicitis score (PAS), in all patients who had an appendicectomy over a one-year period. Methods: Retrospective study of 56 patients aged 4-15 years, who underwent an emergency appendicectomy. PAS was applied and patients were divided according to the PAS protocol into high probability and low probability groups. These results were then correlated with histology. Results: The PAS had sensitivity 0.87, specificity 0.59, positive pr...

Goulder F; Simpson T

2008-01-01

299

Análise bayesiana na estimação de correlações genéticas entre escores visuais e características reprodutivas de bovinos Nelore utilizando modelos linear-limiar / Bayesian analysis in the estimation of genetic correlations between visual scores and reproductive traits in Nelore cattle using linear-threshold models  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese Estimaram-se as correlações genéticas entre os escores visuais e as características reprodutivas, utilizando a estatística bayesiana sob modelo animal linear-limiar, em bovinos da raça Nelore. Foram estudadas características categóricas morfológicas, avaliadas visualmente aos oito, 15 e 22 meses de [...] idade; e características contínuas de perímetro escrotal padronizado aos 365 e 450 dias de idade, além da idade ao primeiro parto. As estimativas de correlações genéticas foram de sentido favorável à seleção, apresentando magnitudes moderadas, sugerindo que a seleção de animais para um biótipo desejável pode levar a animais com maior fertilidade e precocidade sexual. As estimativas de correlação genética para o perímetro escrotal padronizado aos 450 dias e a idade ao primeiro parto com as características morfológicas avaliadas aos 22 meses de idade foram maiores do que as obtidas entre as características de escores visuais avaliadas aos oito e 15 meses de idade. A utilização de escores visuais como critério de seleção trará progresso genético também para as características reprodutivas. Abstract in english The genetic correlations between visual scores and reproductive traits, using the bayesian statistic under the linear-threshold animal model, in bovines of the Nelore breed were estimated. Categorical morphological traits were also evaluated at eight, 15, and 22 month-old, concerning musculature, ph [...] ysical structure, conformation and sacrum, the escrotal circumferences measured at the ages of 365 and 450-day-old, and the age at first calving. The estimates of genetic correlations were moderates, suggesting that the selection of animals with better morphological conformation may lead to animals more precocious and with greater fertility. The estimates of genetic correlation concerning the escrotal circumference at 450 day-old and the age at first calving with the evaluated visual scores at 22 month-old were higher than the ones obtained between visual scores at eight and 15 month-old. The use of these visual scores as a criterion of selection may also bring genetic progress to the reproductive traits.

C.U., Faria; C.U., Magnabosco; L.G., Albuquerque; A., de los Reyes; L.A.F., Bezerra; R.B., Lôbo.

2009-08-01

300

Credit Scoring Modeling  

Directory of Open Access Journals (Sweden)

Full Text Available It is generally easier to predict defaults accurately if a large data set (including defaults is available for estimating the prediction model. This puts not only small banks, which tend to have smaller data sets, at disadvantage. It can also pose a problem for large banks that began to collect their own historical data only recently, or banks that recently introduced a new rating system. We used a Bayesian methodology that enables banks with small data sets to improve their default probability. Another advantage of the Bayesian method is that it provides a natural way for dealing with structural differences between a bank’s internal data and additional, external data. In practice, the true scoring function may differ across the data sets, the small internal data set may contain information that is missing in the larger external data set, or the variables in the two data sets are not exactly the same but related. Bayesian method can handle such kind of problem.

Siana Halim

2014-01-01

 
 
 
 
301

Correlation of signal intensity ratio on orbital MRI-TIRM and clinical activity score as a possible predictor of therapy response in Graves' orbitopathy - a pilot study at 1.5 T  

Energy Technology Data Exchange (ETDEWEB)

This study seeks to describe the predictive value of the signal intensity ratio (SIR) in magnetic resonance imaging-turbo inversion recovery magnitude (MRI-TIRM) in patients with Graves' orbitopathy (GO) with regard to predictability of therapy response. Included in this prospective pilot study were 36 consecutive patients with GO and 25 control subjects. Patients were clinically assessed according to the European Group on Graves' Orbitopathy recommendations with active GO defined by a clinical activity score (CAS) {>=} 3. On magnetic resonance (MR) imaging, muscle inflammation was measured with a region of interest set within the brightest extra-ocular muscle both on coronal turbo inversion recovery magnitude (TIRM) and on fat suppressed gadolinium-enhanced T1-weighted sequences. To calculate the SIR, the measured signal intensity was set in proportion to that of the ipsilateral temporalis muscle. Signal intensity ratio in coronal T2-weighted TIRM sequences in either group ranged from 1.22 to 4.92 (mean 2.04) in patients with GO and from 1.18 to 2.4 (mean 1.63) in controls without GO. The observed differences were significant on the TIRM sequences (right eye p = 0.023; left eye p = 0.022), whereas, no significant differences could be detected on the T1-weighted sequences (right eye p = 0.396; left eye p = 0.498). A cut off value of SIR > 2.5 for a CAS {>=} 4 to discriminate active from inactive patients was statistically calculated. T2 relaxation time is a reliable tool in detecting active GO. The difference in T2-SIR versus T1-SIR is helpful to distinguish inflammatory oedema of the extra ocular muscles from intra-orbital congestion due to reduced venous outflow. (orig.)

Kirsch, Eberhard C.; Kaim, Achim H. [Hirslanden Clinic Aarau, Neuroradiology and Cranio-Facial-Center Hirslanden, Aarau (Switzerland); Oliveira, Marion Gregorio de [University Eye Clinic Basel, Basel (Switzerland); Arx, Georg von [basedow.ch, Interdiscipinary Centre for Graves' Orbitopathy, Olten (Switzerland)

2010-02-15

302

Validating MMI scores: are we measuring multiple attributes?  

Science.gov (United States)

The multiple mini-interview (MMI) used in health professional schools' admission processes is reported to assess multiple non-cognitive constructs such as ethical reasoning, oral communication, or problem evaluation. Though validation studies have been performed with total MMI scores, there is a paucity of information regarding how well MMI scores differentiate the constructs being measured, the relationship between MMI scores (construct or total) and personality characteristics, and how well MMI scores (construct or total) predict future performance in practice. Results from these studies could assist with MMI station development, rater training, score interpretation, and resource allocation. The purpose of this study was to investigate the validity of MMI construct scores (oral communication and problem evaluation), and their relationship to personality measures (emotionality and extraversion) and specific scores from standardized clinical communications interviews (building the relationship and explaining and planning). Confirmatory factor analysis results support a two factor MMI model, however the correlation between these factors was .87. Oral communication MMI scores significantly correlated with extraversion (r c = .25, p developing MMI stations and scoring rubrics for attributes identified as important for future success in school and practice. PMID:24449121

Oliver, Tom; Hecker, Kent; Hausdorf, Peter A; Conlon, Peter

2014-08-01

303

Scores on field independence and performance in snooker.  

Science.gov (United States)

The purpose of this study was to compare the scores on the Group Embedded Figures Test, a measure of field dependence, for 25 male intermediate-level snooker players with scores of 25 intermediate-level sportsmen engaged in soccer, rugby, field hockey, and tennis and to examine the relation between scores on field dependence and performance on a snooker decision-making test. All the snooker players also took a test of decision making in snooker. The snooker players scored significantly more field independent than the sports-science majors on the Group Embedded Figures Test. A Pearson correlation of 0.78 was obtained between scores on the Group Embedded Figures Test and the decision-making test. As there may be an association between scores on field dependence and decision making in snooker, further research should examine sports like lawn bowls and pool where decisions are made in a static environment. PMID:8170763

McMorris, T; Francis, M; MacDonald, A; Priday, K

1993-12-01

304

Association between value-based purchasing score and hospital characteristics  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Medicare hospital Value-based purchasing (VBP program that links Medicare payments to quality of care will become effective from 2013. It is unclear whether specific hospital characteristics are associated with a hospital’s VBP score, and consequently incentive payments. The objective of the study was to assess the association of hospital characteristics with (i the mean VBP score, and (ii specific percentiles of the VBP score distribution. The secondary objective was to quantify the associations of hospital characteristics with the VBP score components: clinical process of care (CPC score and patient satisfaction score. Methods Observational analysis that used data from three sources: Medicare Hospital Compare Database, American Hospital Association 2010 Annual Survey and Medicare Impact File. The final study sample included 2,491 U.S. acute care hospitals eligible for the VBP program. The association of hospital characteristics with the mean VBP score and specific VBP score percentiles were assessed by ordinary least square (OLS regression and quantile regression (QR, respectively. Results VBP score had substantial variations, with mean score of 30 and 60 in the first and fourth quartiles of the VBP score distribution. For-profit status (vs. non-profit, smaller bed size (vs. 100–199 beds, East South Central region (vs. New England region and the report of specific CPC measures (discharge instructions, timely provision of antibiotics and beta blockers, and serum glucose controls in cardiac surgery patients were positively associated with mean VBP scores (p Conclusions Although hospitals serving the poor and the elderly are more likely to score lower under the VBP program, the correlation appears small. Profit status, geographic regions, number and type of CPC measures reported explain the most variation among scores.

Borah Bijan J

2012-12-01

305

Cardiovascular risk scores do not account for the effect of treatment: a review  

Digital Repository Infrastructure Vision for European Research (DRIVER)

OBJECTIVE: To compare the strengths and limitations of cardiovascular risk scores available for clinicians in assessing the global (absolute) risk of cardiovascular disease. DESIGN: Review of cardiovascular risk scores. DATA SOURCES: Medline (1966 to May 2009) using a mixture of MeSH terms and free text for the keywords 'cardiovascular', 'risk prediction' and 'cohort studies'. ELIGIBILITY CRITERIA FOR SELECTING STUDIES: A study was eligible if it fulfilled the following criteria: (1) it was a...

Liew, Sm; Doust, J.; Glasziou, P.

2011-01-01

306

Student-Centered Reliability, Concurrent Validity and Instructional Sensitivity in Scoring of Students' Concept Maps in a University Science Laboratory  

Science.gov (United States)

Student-centered approach of scoring the concept maps consisted of three elements namely symbol system, individual portfolio and scoring scheme. We scored student-constructed concept maps based on 5 concept map criteria: validity of concepts, adequacy of propositions, significance of cross-links, relevancy of examples, and interconnectedness. With…

Kaya, Osman Nafiz; Kilic, Ziya

2004-01-01

307

A scoring system for the assessment of angiographic findings in non-occlusive mesenteric ischemia (NOMI)  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To establish a standardized scoring system for angiographic findings in patients with non-occlusive mesenteric ischemia (NOMI). Materials and Methods: In 36 patients (mean age: 72 years), 53 angiographies of the superior mesenteric artery (SMA) were performed for suspected NOMI after cardiac or major aortic surgery. All examinations were performed using a standardized DSA technique. Two experienced radiologists performed a consensus reading blinded to the clinical information, on two occasions with an interval of two weeks. In order to investigate the reproducibility of the criteria, the images were assessed once by an intensivist and a medical student. Image analysis was performed with respect to vessel morphology, reflux of contrast medium into the aorta, small bowel parenchymal contrast enhancement and distension and the delay between arterial injection and portal vein filling. Results: Almost perfect intra-observer correlation was obtained for the assessment of the contrast medium reflux ({kappa} = 0.82) and substantial correlation for the time of portal vein filling ({kappa} = 0.66). Moderate correlations were obtained for the vessel morphology ({kappa} = 0.51), small bowel enhancement ({kappa} = 0.63) and distension ({kappa} = 0.53). Contrast medium reflux into the aorta ({kappa} = 0.77 and 0.63) and the time of portal vein filling ({kappa} = 0.42 and 0.58) resulted in the highest inter-observer correlations between the radiologists and the intensivist as well as the radiologists and the student. Conclusion: In patients with suspected NOMI, using our scoring system yields high intra- and inter-observer correlations, allowing a standardized evaluation of angiographic findings. (orig.)

Minko, P.; Stroeder, J.; Miodek, J.; Buecker, A.; Katoh, M. [Saarland Univ. Hospital, Homburg/Saar (Germany). Diagnostic and Interventional Radiology; Groesdonk, H.; Schaefers, H.J. [Saarland Univ. Hospital, Homburg/Saar (Germany). Dept. of Thoracic and Cardiovascular Surgery; Graeber, S. [Saarland Univ. Hospital, Homburg/Saar (Germany). Inst. of Medical Biometry, Epidemiology and Medical Informatics

2012-09-15

308

Propensity score matching in SPSS  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Propensity score matching is a tool for causal inference in non-randomized studies that allows for conditioning on large sets of covariates. The use of propensity scores in the social sciences is currently experiencing a tremendous increase; however it is far from a commonly used tool. One impediment towards a more wide-spread use of propensity score methods is the reliance on specialized software, because many social scientists still use SPSS as their main analysis tool. Th...

Thoemmes, Felix

2012-01-01

309

A comparison of A? amyloid pathology staging systems and correlation with clinical diagnosis.  

Science.gov (United States)

Current neuropathological Alzheimer's disease (AD) criteria from the National Institute on Aging-Alzheimer's Association (NIA-AA) incorporate two staging systems for A? pathology, namely the Thal A? phase (TAP) and the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) methods. The goal of this study was to compare and contrast results obtained with these two different staging systems for A? pathology since this is critical for future correlations of A? amyloid imaging data with A? neuropathology data based on immunohistochemical detection of A? deposits. A total of 123 cases, divided into 82 training and 41 validation cases, with a diagnosis of either unremarkable adult brain (normal) or AD and CERAD scores ranging from none to frequent were included. There was no clear and consistent relationship between CERAD and the TAP A? scores with the exception of scores for the highest plaque burdens (i.e., CERAD C3 and TAP A3) in the cases studied here. However, we developed an algorithm that relates CERAD scores to TAP scores with high agreement (94 % in training and 98 % in the validation set). In addition, TAP scores were a better predictor of dementia (sensitivity of 94 % specificity 87.7 %) than CERAD scores (sensitivity of 57 % specificity 100 %). Yet, further research is needed to define strategies to relate CERAD and TAP A? plaque scores to compare their utility and for determining the clinical associations of these different amyloid staging systems with aging and AD. PMID:24916271

Boluda, Susana; Toledo, Jon B; Irwin, David J; Raible, Kevin M; Byrne, Matt D; Lee, Edward B; Lee, Virginia M-Y; Trojanowski, John Q

2014-10-01

310

Score_set: A CAPRI benchmark for scoring protein complexes.  

Science.gov (United States)

Critical Assessment of PRedicted Interactions (CAPRI) has proven to be a catalyst for the development of docking algorithms. An essential step in docking is the scoring of predicted binding modes in order to identify stable complexes. In 2005, CAPRI introduced the scoring experiment, where upon completion of a prediction round, a larger set of models predicted by different groups and comprising both correct and incorrect binding modes, is made available to all participants for testing new scoring functions independently from docking calculations. Here we present an expanded benchmark data set for testing scoring functions, which comprises the consolidated ensemble of predicted complexes made available in the CAPRI scoring experiment since its inception. This consolidated scoring benchmark contains predicted complexes for 15 published CAPRI targets. These targets were subjected to 23 CAPRI assessments, due to existence of multiple binding modes for some targets. The benchmark contains more than 19,000 protein complexes. About 10% of the complexes represent docking predictions of acceptable quality or better, the remainder represent incorrect solutions (decoys). The benchmark set contains models predicted by 47 different predictor groups including web servers, which use different docking and scoring procedures, and is arguably as diverse as one may expect, representing the state of the art in protein docking. The data set is publicly available at the following URL: http://cb.iri.univ-lille1.fr/Users/lensink/Score_set. Proteins 2014; 82:3163-3169. © 2014 Wiley Periodicals, Inc. PMID:25179222

Lensink, Marc F; Wodak, Shoshana J

2014-11-01

311

Intussusception in infancy and childhood: evaluation of a prognostic scoring pattern.  

Directory of Open Access Journals (Sweden)

Full Text Available This is a retrospective analysis of 82 patients of intussusception in infancy and childhood. Males were more than females in the ratio 2.4 : 1, the ages varied from 2 months to 12 years. Majority (73% were less than 1 year old. Commonest presentations were pain, vomiting, distension, palpable lump and blood and mucus in stools. The management of these patients varied from barium enema reduction (3 cases, reduction by surgery and manipulation (59 cases and resection with primary anastomosis (20 cases. We analysed our patients by giving scores based on clinical criteria. We concluded that the patients in our circumstances do not show any correlation of the scoring pattern with morbidity or mortality, chances of reduction by barium enema or manually. Resection, however, did correlate with a high incidence of death (75%. Resections were required slightly more in ileo-ileal intussusceptions than in those having a colonic involvement, morbidity in the form of wound dehiscence, and sepsis was higher in those patients who had undergone resections.

Rege V

1991-04-01

312

Empathic veterinarians score cattle pain higher.  

Science.gov (United States)

The treatment of cattle pain often relies upon veterinarians. The aim of this study was to qualify the influence of veterinarians skills, attitudes, and empathy on cattle pain assesment and consequently disbudding pain management. A web-based questionnaire was sent to Finnish veterinary students in either the preclinical or clinical stage, and also to production-animal practice oriented veterinarians. The questionnaire recorded demographics, statements of opinions, pain scoring of cattle conditions and procedures. Empathy towards humans (Interpersonal Reactivity Index, IRI) and reworded IRI to measure empathy towards animals were also covered. The overall response rate was approximately 40%. The association between pain and empathy scores were analyzed by Pearson?s correlation, and the factors affecting pain scores and empathy towards animals analyzed using linear models. The need for pain medication of calves during disbudding was well recognized and the intention to treat such pain was very common. Higher mean scores for cattle pain were associated with greater empathy towards humans. On average, respondents' empathy towards animals was greater than towards humans, and was associated with respondents' empathy towards humans, family size and attachment to family pet. PMID:24685101

Norring, Marianna; Wikman, Ingela; Hokkanen, Ann-Helena; Kujala, Miiamaaria V; Hänninen, Laura

2014-04-01

313

The Bookmark Procedure for Setting Cut-Scores and Finalizing Performance Standards: Strengths and Weaknesses  

Science.gov (United States)

The Bookmark standard-setting procedure was developed to address the perceived problems with the most popular method for setting cut-scores: the Angoff procedure (Angoff, 1971). The purposes of this article are to review the Bookmark procedure and evaluate it in terms of Berk's (1986) criteria for evaluating cut-score setting methods. The…

Lin, Jie

2006-01-01

314

Conservative treatment of soft tissue sarcomas of the extremities. Functional evaluation with LENT-SOMA scales and the Enneking score  

International Nuclear Information System (INIS)

Objective. - The aim of this prospective study is the feasibility of late effects assessment by LENT-SOMA scales after conservative treatment of soft tissue sarcomas of the extremities and a comparison with the functional evaluation by the Enneking score. Patients and methods. - During the systematic follow-up consultations, a series of 32 consecutive patients was evaluated in terms of late effects by LENT SOMA scales and functional results by the Enneking score. The median time after treatment was 65 months. The treatment consisted of conservative surgery (all cases) followed by radiation therapy (29 cases), often combined with adjuvant therapy (12 concomitant radio-chemotherapy association cases out of 14). The assessment of the toxicity was retrospective for acute effects and prospective for the following late tissue damage: skin/subcutaneous tissues, muscles/soft tissues and peripheral nerves. Results. -According to the Enneking score, the global score for the overall series was high (24/30) despite four the scores zero for the psychological acceptance. According to LENT SOMA scales, a low rate of severe sequelae (grade 3-4) was observed. The occurrence of high-grade sequelae and their functional consequences were not correlated with quality of exeresis, dose of radiotherapy or use of concomitant chemotherapy. A complementarity was observed between certain factors of the Enneking score and some criteria of the LENTSOMA scales, especially of muscles/soft tissues. Cles, especially of muscles/soft tissues. Conclusion. -The good quality of functional results was confirmed by the two mean scoring systems for late normal tissue damage. The routine use of LENT-SOMA seems to be more time consuming than the Enneking score (mean time of scoring: 1 3 versus five minutes). The LENT-SOMA scales are aimed at a detailed description of late toxicity and sequelae while the Enneking score provides a more global evaluation, including the psychological acceptance of treatment. The late effects assessment by the LENT-SOMA scales should be carried on in prospectives studies, especially in case of concomitant radio-chemotherapy. (author)

315

The Machine Scoring of Writing  

Science.gov (United States)

This article provides an introduction to the kind of computer software that is used to score student writing in some high stakes testing programs, and that is being promoted as a teaching and learning tool to schools. It sketches the state of play with machines for the scoring of writing, and describes how these machines work and what they do.…

McCurry, Doug

2010-01-01

316

Interpreting Linked Psychomotor Performance Scores  

Science.gov (United States)

Given that equating/linking applications are now appearing in kinesiology literature, this article provides an overview of the different types of linked test scores: equated, concordant, and predicted. It also addresses the different types of evidence required to determine whether the scores from two different field tests (measuring the same…

Looney, Marilyn A.

2013-01-01

317

Sensibilidad y especificidad de la escala de Alvarado en apendicitis aguda en el Hospital Regional de Alta Especialidad de Veracruz / Sensitivity and specificity of the Alvarado score in acute appendicitis, and its anatomopatological correlation at the High Specialty Regional Hospital of Veracruz  

Scientific Electronic Library Online (English)

Full Text Available SciELO Mexico | Language: Spanish Abstract in spanish Objetivo: Determinar la sensibilidad y especificidad de la escala de Alvarado en el diagnóstico de apendicitis aguda en el Hospital Regional de Alta Especialidad de Veracruz. Sede: Hospital de alta especialidad de Veracruz. Diseño: Estudio transversal, ambispectivo, descriptivo, observacional. Análi [...] sis estadístico: Regresión logística binaria, chi cuadrada (?²), razón de momios y curvas ROC. Resultados: Se incluyeron 384 (293 retrospectivos y 91 prospectivos) pacientes con diagnóstico de probable apendicitis y que fueron operados. Mediante un análisis estadístico se encontró que con la escala de Alvarado en el punto de corte >5 se obtiene una mayor precisión diagnóstica, con sensibilidad de 0.96%, especificidad de 0.72, valor predictivo positivo de 0.93% y valor predictivo negativo de 0.82. El criterio más encontrado fue el dolor en fosa iliaca derecha, positivo en el 100% de pacientes intervenidos con apendicitis; sin embargo, el más específico fue el rebote con 94.3% de los pacientes. Conclusión: Los criterios de Alvarado son una herramienta útil para el diagnóstico de apendicitis aguda, son aplicables en todos los pacientes con dolor abdominal agudo sugestivo de apendicitis como prueba al ingreso y para descartar patología apendicular en 5 puntos o menos. Abstract in english Objective: To determine the sensitivity and specificity of the Alvarado Score for the diagnosis of acute appendicitis at a high specialty regional hospital. Setting: High specialty regional hospital in the city of Veracruz, Veracruz, Mexico. Design: Cross-sectional, descriptive, ambispective observa [...] tional study. Statistical analysis: Binary logistic regression, chi square (?2), odds ratio and ROC curves. Results: The study included 384 (293 retrospective and 91 prospective) patients with a diagnosis of probable appendicitis and who were operated. Statistical analysis revealed that a better diagnostic accuracy is achieved with the Alvarado Score at a cut off >5, with a sensitivity of 0.96%, specificity of 0.72, positive predictive value of 0.93% and negative predictive value of 0.82. The most frequently found criterion was pain in the right iliac fossa positive in 100% of patients with appendicitis subjected to surgery; however, the most specific criterion was the rebound with 94.3% of patients. Conclusion: Criteria of the Alvarado Score are a useful tool for the diagnosis of acute appendicitis, it is applicable to all patients with acute abdominal pain suggestive of appendicitis as an admittance test, and to discard appendicular pathology in 5 points or less.

Luis, Hernández Miguelena; David Román, Domínguez Solano.

2012-09-01

318

Sensibilidad y especificidad de la escala de Alvarado en apendicitis aguda en el Hospital Regional de Alta Especialidad de Veracruz / Sensitivity and specificity of the Alvarado score in acute appendicitis, and its anatomopatological correlation at the High Specialty Regional Hospital of Veracruz  

Scientific Electronic Library Online (English)

Full Text Available SciELO Mexico | Language: Spanish Abstract in spanish Objetivo: Determinar la sensibilidad y especificidad de la escala de Alvarado en el diagnóstico de apendicitis aguda en el Hospital Regional de Alta Especialidad de Veracruz. Sede: Hospital de alta especialidad de Veracruz. Diseño: Estudio transversal, ambispectivo, descriptivo, observacional. Análi [...] sis estadístico: Regresión logística binaria, chi cuadrada (?²), razón de momios y curvas ROC. Resultados: Se incluyeron 384 (293 retrospectivos y 91 prospectivos) pacientes con diagnóstico de probable apendicitis y que fueron operados. Mediante un análisis estadístico se encontró que con la escala de Alvarado en el punto de corte >5 se obtiene una mayor precisión diagnóstica, con sensibilidad de 0.96%, especificidad de 0.72, valor predictivo positivo de 0.93% y valor predictivo negativo de 0.82. El criterio más encontrado fue el dolor en fosa iliaca derecha, positivo en el 100% de pacientes intervenidos con apendicitis; sin embargo, el más específico fue el rebote con 94.3% de los pacientes. Conclusión: Los criterios de Alvarado son una herramienta útil para el diagnóstico de apendicitis aguda, son aplicables en todos los pacientes con dolor abdominal agudo sugestivo de apendicitis como prueba al ingreso y para descartar patología apendicular en 5 puntos o menos. Abstract in english Objective: To determine the sensitivity and specificity of the Alvarado Score for the diagnosis of acute appendicitis at a high specialty regional hospital. Setting: High specialty regional hospital in the city of Veracruz, Veracruz, Mexico. Design: Cross-sectional, descriptive, ambispective observa [...] tional study. Statistical analysis: Binary logistic regression, chi square (?2), odds ratio and ROC curves. Results: The study included 384 (293 retrospective and 91 prospective) patients with a diagnosis of probable appendicitis and who were operated. Statistical analysis revealed that a better diagnostic accuracy is achieved with the Alvarado Score at a cut off >5, with a sensitivity of 0.96%, specificity of 0.72, positive predictive value of 0.93% and negative predictive value of 0.82. The most frequently found criterion was pain in the right iliac fossa positive in 100% of patients with appendicitis subjected to surgery; however, the most specific criterion was the rebound with 94.3% of patients. Conclusion: Criteria of the Alvarado Score are a useful tool for the diagnosis of acute appendicitis, it is applicable to all patients with acute abdominal pain suggestive of appendicitis as an admittance test, and to discard appendicular pathology in 5 points or less.

Luis, Hernández Miguelena; David Román, Domínguez Solano.

319

Inflamed conjunctival nevi: histopathological criteria.  

Science.gov (United States)

Inflamed conjunctival nevi (ICN) may suggest malignancy because of their rapid growth and atypical histology. The objective of this study was to characterize the diagnostic features of ICN. A retrospective, nonrandomized study of 13 patients with ICN was conducted. A scoring method was developed based on histology and immunopathological parameters. The presence of epithelial solid or cystic inclusions and the preservation of goblet cells are consistent with a benign melanocytic lesion. Periodic acid-Schiff stain and immunohistochemistry to identify the epithelial component prove helpful in the differential diagnosis for melanoma. Polyclonal lymphoid infiltrate and benign cytological features of ICN exclude a diagnosis of lymphoma. Despite the presence of immunoglobulin 4-positive plasma cells in the lesions, ICN does not meet the diagnostic criteria for immunoglobulin 4-related disease. Most patients with ICN are young. The treatment for ICN is complete excision, and the prognosis is excellent. PMID:25171709

Choi, Eunice K; Chévez-Barrios, Patricia

2014-09-01

320

Quantitative criteria for insomnia.  

Science.gov (United States)

Formal diagnostic systems (DSM-IV, ICSD, and ICD-10) do not provide adequate quantitative criteria to diagnose insomnia. This may not present a serious problem in clinical settings where extensive interviews determine the need for clinical management. However, lack of standard criteria introduce disruptive variability into the insomnia research domain. The present study reviewed two decades of psychology clinical trials for insomnia to determine common practice with regard to frequency, severity, and duration criteria for insomnia. Modal patterns established frequency (> or =3 nights a week) and duration (> or =6 months) standard criteria. We then applied four versions of severity criteria to a random sample and used sensitivity-specificity analyses to identify the most valid criterion. We found that severity of sleep onset latency or wake time after sleep onset of: (a) > or =31 min; (b) occurring > or =3 nights a week; (c) for > or =6 months are the most defensible quantitative criteria for insomnia. PMID:12643966

Lichstein, K L; Durrence, H H; Taylor, D J; Bush, A J; Riedel, B W

2003-04-01

 
 
 
 
321

Environmental risk evaluation criteria  

DEFF Research Database (Denmark)

This paper describes an approach to incorporating environmental risk evaluation criteria within IMO’s guidelines for Formal Safety Assessment (FSA). Such criteria are currently absent from FSA, and the discussion to include them has just started. Said criteria are relevant for evaluating on a cost-benefit basis Risk Control Options (RCOs) for reducing oil spill pollution risk. Oil pollution may comefrom any ship, including bunker spills from non-tank vessels. RCOs are not necessarily ship-based, and may include vessel traffic management information systems (VTMIS) and other options. The proposed approach may be useful in extending FSA to cover environmental risk evaluation criteria and combines such criteria with criteria already in use in FSA. It can also readily be extended to environmental consequences other than oil pollution. Recent IMO developments on this matter are also reported.

Psaraftis, Harilaos N.

2008-01-01

322

A comparison study of the post anesthesia recovery score and pulse oximetry.  

Science.gov (United States)

Since the 1970s the Post Anesthesia Recovery Score (PARS), a numerical scoring of patient status in five areas, has been used in the PACU to assist in the assessment of patient condition by nurses. It has been used to give information to determine discharge criteria from the PACU. It is also used for the determination of patient need for oxygen therapy. Its reliability and validity have been tested. In the early 1980s pulse oximeters were developed to noninvasively monitor patients' oxygen saturation. Accuracy of the pulse oximeters has been tested against arterial blood gas findings. This instrument is also used to determine patient discharge status from the PACU and patient need for oxygen therapy. A group of 28 outpatients in the ambulatory surgery center were observed and monitored every 15 minutes with readings documented in the first postoperative hour after receiving local anesthesia with intravenous sedation. Using both the PARS and the pulse oximeter, scores were compared as indicators of subject need for oxygen therapy in the PACU. Included in the study group were twelve males and sixteen females aged 22 to 94 years. A pilot study, performed 1 week before the actual study, monitored six of these subjects. The data from the pilot study was not included in the actual study results. Subjects underwent a variety of same-day, elective surgical procedures. Since no previous standard of comparison for the PARS and pulse oximetry readings was found in the literature, a comparison table was developed. The data showed a 93% correlation of scores between the two instruments with only a 7% inconsistency.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:2113098

Naimark, T M

1990-06-01

323

Moving the Cut Score on Rasch Scored Tests.  

Science.gov (United States)

Presents empirically based item selection guidelines for moving the cut score on equated tests consisting of "n" dichotomous items calibrated assuming the Rasch model. Derivations of lemmas that underlie the guidelines are provided as well as a simulated example. (SLD)

Miller, G. Edward; Beretvas, S. Natasha

2002-01-01

324

International Validation of the Low Anterior Resection Syndrome Score  

DEFF Research Database (Denmark)

OBJECTIVE:: The aims of this study were to investigate the convergent and discriminative validity and reliability of the low anterior resection syndrome (LARS) score in an international setting. BACKGROUND:: The LARS score is a simple self-administered questionnaire measuring bowel dysfunction after rectal cancer surgery. The score is intended to be commonly used in international research and clinical practice in the future. Therefore, a thorough validation in an international setting is of utmost importance. METHODS:: The LARS score was translated using methods in keeping with current international recommendations. A total of 801 patients operated for rectal cancer in Sweden, Spain, Germany, and Denmark completed the LARS score questionnaire, including an anchor question assessing the impact of bowel function on quality of life. A subgroup of 218 patients completed the LARS score twice. Data were analyzed per country. RESULTS:: The LARS score has demonstrated a high convergent validity in terms of a high correlation between LARS score and quality of life (P <0.001). Sensitivity ranged from 67.7% to 88.3% and specificity from 58.1% to 86.3%. The LARS score was able to discriminate between groups of patients differing with regard to radiotherapy, surgery, and age (P <0.05). The score also demonstrated high reliability at test-retest with narrow limits of agreement and no statistically significant difference between scores at the first and second test. CONCLUSIONS:: The Swedish, Spanish, German, and Danish versions of the LARS score have proven to be valid and reliable tools for measuring LARS in European rectal cancer patients.

Juul, Therese; Ahlberg, Madelene

2013-01-01

325

Correlation between subtalar varus angle and disability in patients with patellofemoral arthritis  

Directory of Open Access Journals (Sweden)

Full Text Available Aim: To find the correlation between subtalar varus angle & disability in patients with patellofemoral arthritis. Methods: A total of 30 subjects aged (48.86±5.74 referred to the department of physiotherapy, with patellofemoral arthritis and fulfilling the criteria of inclusion were recruited for the study, sampling method being convenient sampling. Disability score was measured of each patient by WOMAC index (Western Ontario and McMaster Universities Index of Osteoarthritis disability questionnaire and subtalar varus angle was measured in non weight bearing position in prone lying. Results: Pearson’s correlation coefficient test showed a highly significant (p=0.000 positive correlation (r=0.821 between disability scores and subtalar varus angle. Conclusion: There is a highly significant relation between disabilities due to patellofemoral pain in patellofemoral arthritis patients and sub talar varus angle

Patel Birenkumar Jagdishbhai

2009-11-01

326

Influence of low-stress handling on reactivity score and pregnancy rate during fixed-time artificial insemination in Nellore cows  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in english The objective of this work was to evaluate the influence of low-stress handling (LSH) on reactivity score and pregnancy rate during fixed-time artificial insemination (FTAI) for extensively raised Nellore cows. Multiparous cows (n = 126) were randomly allocated into two groups: G1 (n = 66) and G2, t [...] he control group (n = 60). Group G1 was subjected to LSH, in which the animals were handled in a calm and quiet manner, without loud noises or physical aggression, using the point of balance, respecting the flight zone and using flags to supplement handling. Group G2 was handled following the typical procedure, with yelling, kicking and the use of electric prods and sticks. On D0, D8 and D10, FTAI was performed in both groups. Reactivity was scored on D0, D8 and D10 at the squeeze chute, based on the tension score, breathing score, and bellowing score. Using the three criteria above, the reactivity scores were defined as follows: R1 (calm); R2 (slightly reactive); R3 (moderately reactive); R4 (reactive); and R5 (highly reactive). Thirty-five days after artificial insemination, pregnancy was determined using ultrasonography. There was no significant correlation between reactivity score and pregnancy rate in each group or between the pregnancy rates in both groups. However, there was a statistically significant difference between the G1 and G2 groups with regard to reactivity score (1.62±0.05 vs. 2.12±0.07). Low-stress handling influenced reactivity but did not affect pregnancy rate in extensively raised Nellore cows subjected to FTAI.

Rayf Roberto, Tirloni; Fábio Alcântara, Rocha; Fábio José, Lourenço; Lílian Rigatto, Martins.

2013-07-01

327

Comparison between needle biopsy and radical prostatectomy samples in assessing Gleason score and modified Gleason score in prostatic adenocarcinomas  

Directory of Open Access Journals (Sweden)

Full Text Available Histologic grading is an important predictor of prostatic disease stage and prognosis. We aimed to assess the degree of concordance between pathologic characteristics of the specimens obtained from biopsy and radical prostatectomy materials.Gleason scores and modified Gleason scores calculated for 25 cases of prostatic adenocarcinoma from both needle biopsy and radical prostatectomy specimens were analyzed.Mean Gleason scores for biopsy and radical specimens were 6.4 (SD:±0.7 and 6.64 (SD:±1.3; and corresponding modified Gleason scores were 7.32 (SD:±1.43 and 7.32 (SD:±0.98, respectively. The Gleason scores of biopsy and radical prostatectomy specimens were identical in 48% (12/25 of the cases, while 32% (8/25 of the biopsy specimens were over-and 20% (5/25 of them were undergraded. While assessing modified Gleason scores, the exact degree of concordance of biopsy specimens with radical prostatectomy materials was 56% (14/25 and of the 11 (44% cases not correlated exactly, 6 (24% were over- and 5 (20% were undergraded. When the exact, over- and underestimated scores of Gleason and modified Gleason grading systems were compared statistically, no difference between two groups was seen (p>0.05. Overgrading errors were found to be more than undergrading errors for both of the scoring systems. Using either the modified Gleason or traditional Gleason scoring

Banu DO?AN GÜN

2007-01-01

328

Characterization of Tripartite Quantum States with Vanishing Monogamy Score  

CERN Document Server

Quantum discord, an information-theoretic quantum correlation measure, can satisfy as well as violate monogamy, for three-party quantum states. We quantify the feature using the concept of discord monogamy score. We find a necessary condition of vanishing discord monogamy score for arbitrary three-party states. A necessary and sufficient condition is obtained for pure states. We prove that the class of states having a vanishing discord monogamy score cannot have arbitrarily high genuine multipartite entanglement, as quantified by generalized geometric measure. In the special case of three-qubit pure states, their classification with respect to the discord monogamy score, reveals a rich structure that is different from that had been obtained by using the monogamy score corresponding to the entanglement measure called concurrence. We investigate properties like genuine multipartite entanglement and violation of multipartite Bell inequality for these states.

Bera, Manabendra N; De, Aditi Sen; Sen, Ujjwal

2012-01-01

329

Maximum-Score Diversity Selection  

Digital Repository Infrastructure Vision for European Research (DRIVER)

This thesis discusses the problem of Maximum-Score Diversity Selection (MSDS). Pure diversity selection, as it is often performed e.g. in early drug discovery, is the selection of a subset of available objects that is as diverse as possible. MSDS adds a second objective, which additionally tries to maximize the "score'' of the subset, which usually is the sum of scores of all elements in the subset. Thus, this problem is a classical multi-objective optimization problem since both objectives ...

Meinl, Thorsten

2010-01-01

330

Estimating WISC-III Scores for Special Education Students Using the Dumont-Faro Short Form.  

Science.gov (United States)

Uses the Dumont-Faro short form to estimate the Wechsler Intelligence Scales for Children-III (WISC-III) Full Sale IQ scores for 45 special education students. Results demonstrate that IQ scores were positively correlated with the WISC-III Full Scale scores. However an IQ miscalculation rate of 44% challenges the utility of the Dumont-Faro short…

Comninel, Mary E.; Bordieri, James E.

2001-01-01

331

Development of a software tool and criteria evaluation for efficient design of small interfering RNA.  

Science.gov (United States)

RNA interference can be used as a tool for gene silencing mediated by small interfering RNAs (siRNA). The critical step in effective and specific RNAi processing is the selection of suitable constructs. Major design criteria, i.e., Reynolds's design rules, thermodynamic stability, internal repeats, immunostimulatory motifs were emphasized and implemented in the siRNA design tool. The tool provides thermodynamic stability score, GC content and a total score based on other design criteria in the output. The viability of the tool was established with different datasets. In general, the siRNA constructs produced by the tool had better thermodynamic score and positional properties. Comparable thermodynamic scores and better total scores were observed with the existing tools. Moreover, the results generated had comparable off-target silencing effect. Criteria evaluations with additional criteria were achieved in WEKA. PMID:21145307

Chaudhary, Aparna; Srivastava, Sonam; Garg, Sanjeev

2011-01-01

332

criteria for listing review  

Criteria for Listing Review April 2010 1 Contents. 1. Why a review p4. 2. Issues to be addressed. p6. 3. The current criteria. p9. 4. The situation elsewhere. p22. 5. A detailed consideration of the issues. p36. a. Age...

333

Knowledge management review criteria  

International Nuclear Information System (INIS)

The paper presents knowledge management review criteria, which are intended to be used by a nuclear power plant operating organization in conducting a self-assessment or an external review of knowledge management functions. Most of these criteria have been used by IAEA experts during the missions on knowledge management at Krsko nuclear power plant, Slovenia and Kozloduy nuclear power plant, Bulgaria. (author)

334

Neurointerventional Treatment in Acute Stroke. Whom to Treat? (Endovascular Treatment for Acute Stroke: Utility of THRIVE Score and HIAT Score for Patient Selection)  

Energy Technology Data Exchange (ETDEWEB)

Purpose: Intra-arterial therapy (IAT) is used increasingly as a treatment option for acute stroke caused by central large vessel occlusions. Despite high rates of recanalization, the clinical outcome is highly variable. The authors evaluated the Houston IAT (HIAT) and the totaled health risks in vascular events (THRIVE) score, two predicting scores designed to identify patients likely to benefit from IAT. Methods: Fifty-two patients treated at the Stavanger University Hospital with IAT from May 2009 to June 2012 were included in this study. We combined the scores in an additional analysis. We also performed an additional analysis according to high age and evaluated the scores in respect of technical efficacy. Results: Fifty-two patients were evaluated by the THRIVE score and 51 by the HIAT score. We found a strong correlation between the level of predicted risk and the actual clinical outcome (THRIVE p = 0.002, HIAT p = 0.003). The correlations were limited to patients successfully recanalized and to patients <80 years. By combining the scores additional 14.3 % of the patients could be identified as poor candidates for IAT. Both scores were insufficient to identify patients with a good clinical outcome. Conclusions: Both scores showed a strong correlation to poor clinical outcome in patients <80 years. The specificity of the scores could be enhanced by combining them. Both scores were insufficient to identify patients with a good clinical outcome and showed no association to clinical outcome in patients aged {>=}80 years.

Fjetland, Lars, E-mail: lars.fjetland@lyse.net; Roy, Sumit, E-mail: sumit.roy@sus.no; Kurz, Kathinka D., E-mail: kathinka.dehli.kurz@sus.no [Stavanger University Hospital, Department of Radiology (Norway); Solbakken, Tore, E-mail: tore.solbakken@sus.no [Stavanger University Hospital, Department of Neurology (Norway); Larsen, Jan Petter, E-mail: jan.petter.larsen@sus.no; Kurz, Martin W., E-mail: martin.kurz@sus.no [The Norwegian Center for Movement Disorders, Stavanger University Hospital (Norway)

2013-10-15

335

Neurointerventional Treatment in Acute Stroke. Whom to Treat? (Endovascular Treatment for Acute Stroke: Utility of THRIVE Score and HIAT Score for Patient Selection)  

International Nuclear Information System (INIS)

Purpose: Intra-arterial therapy (IAT) is used increasingly as a treatment option for acute stroke caused by central large vessel occlusions. Despite high rates of recanalization, the clinical outcome is highly variable. The authors evaluated the Houston IAT (HIAT) and the totaled health risks in vascular events (THRIVE) score, two predicting scores designed to identify patients likely to benefit from IAT. Methods: Fifty-two patients treated at the Stavanger University Hospital with IAT from May 2009 to June 2012 were included in this study. We combined the scores in an additional analysis. We also performed an additional analysis according to high age and evaluated the scores in respect of technical efficacy. Results: Fifty-two patients were evaluated by the THRIVE score and 51 by the HIAT score. We found a strong correlation between the level of predicted risk and the actual clinical outcome (THRIVE p = 0.002, HIAT p = 0.003). The correlations were limited to patients successfully recanalized and to patients <80 years. By combining the scores additional 14.3 % of the patients could be identified as poor candidates for IAT. Both scores were insufficient to identify patients with a good clinical outcome. Conclusions: Both scores showed a strong correlation to poor clinical outcome in patients <80 years. The specificity of the scores could be enhanced by combining them. Both scores were insufficient to identify patients with a good clinical outcome and showed no association to clinical outcome in patients aged ?80 years

336

Plutonium storage criteria  

Energy Technology Data Exchange (ETDEWEB)

The Department of Energy has issued a technical standard for long-term (>50 years) storage and will soon issue a criteria document for interim (<20 years) storage of plutonium materials. The long-term technical standard, {open_quotes}Criteria for Safe Storage of Plutonium Metals and Oxides,{close_quotes} addresses the requirements for storing metals and oxides with greater than 50 wt % plutonium. It calls for a standardized package that meets both off-site transportation requirements, as well as remote handling requirements from future storage facilities. The interim criteria document, {open_quotes}Criteria for Interim Safe Storage of Plutonium-Bearing Solid Materials{close_quotes}, addresses requirements for storing materials with less than 50 wt% plutonium. The interim criteria document assumes the materials will be stored on existing sites, and existing facilities and equipment will be used for repackaging to improve the margin of safety.

Chung, D. [Scientech, Inc., Germantown, MD (United States); Ascanio, X. [Dept. of Energy, Germantown, MD (United States)

1996-05-01

337

Data Mining the University: College GPA Predictions from SAT Scores  

Digital Repository Infrastructure Vision for European Research (DRIVER)

We analyze a data set comprised of academic records of undergraduates at the University of Oregon from 2000-2004. We find correlations of roughly 0.35 to 0.5 between SAT scores and upper division, in-major GPA (henceforth, GPA). Interestingly, low SAT scores do not preclude high performance in most majors. That is, the distribution of SAT scores after conditioning on high GPA (e.g., 3.5 or even 4.0) typically extends below 1000 (the average among test takers). We hypothesize...

Hsu, Stephen D. H.; Schombert, James

2010-01-01

338

Predicting DMS-IV cluster B personality disorder criteria from MMPI-2 and Rorschach data: a test of incremental validity.  

Science.gov (United States)

Despite their frequent conjoint clinical use, the incremental validity of Rorschach (Rorschach, 1921/1942) and MMPI (Hathaway & McKinley, 1943) data has not been adequately established, nor has any study to date explored the incremental validity of these tests for predicting Diagnostic and Statistical Manual of Mental Disorders (4th ed. [DSM-IV]; American Psychiatric Association, 1994) personality disorders (PDs). In a reanalysis of existing data, we used select Rorschach variables and the MMPI PD scales to predict DSM-IV antisocial, borderline, histrionic, and narcissistic PD criteria in a sample of treatment-seeking outpatients. The correlational findings revealed alimited relation between Rorschach and MMPI-2 (Butcher, Dahlstrom, Graham, Tellegen, & Kaemmer, 1989) variables, with only 5 of 30 correlations reaching significance (p <.05). Hierarchical regression analyses showed that both the MMPI and Rorschach data add incrementally in the prediction of DSM-IV borderline and narcissistic PD total criteria scores. The findings were less clear for the incremental value of Rorschach and MMPI-2 data in predicting the total number of DSM-IV histrionic PD criteria, which were best predicted by Rorschach data, and antisocial PD criteria, which were best predicted by MMPI-2 data. In addition to providing evidence of the incremental validity of Rorschach data, these findings also shed light on the psychological characteristics of the DSM-IV Cluster B PDs. PMID:11206295

Blais, M A; Hilsenroth, M J; Castlebury, F; Fowler, J C; Baity, M R

2001-02-01

339

Association between eating behavior scores and obesity in Chilean children  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Abstract Background Inadequate eating behavior and physical inactivity contribute to the current epidemic of childhood obesity. The aim of this study was to assess the association between eating behavior scores and childhood obesity in Chilean children. Design and methods We recruited 126 obese, 44 overweight and 124 normal-weight Chilean children (6-12 years-old; both genders) according to the International Obesity Task Force (IOTF) criteria. Eating behavior sc...

Amador Paola; Obregón Ana M; Cataldo Rodrigo; Domínguez-Vásquez Patricia; Smalley Susan V; González Andrea; Ho-Urriola Judith A; Santos José L; Weisstaub Gerardo; Isabel, Hodgson M.

2011-01-01

340

Selection criteria of residents for residency programs in Kuwait  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background In Kuwait, 21 residency training programs were offered in the year 2011; however, no data is available regarding the criteria of selecting residents for these programs. This study aims to provide information about the importance of these criteria. Methods A self-administered questionnaire was used to collect data from members (e.g. chairmen, directors, assistants …etc. of residency programs in Kuwait. A total of 108 members were invited to participate. They were asked to rate the importance level (scale from 1 to 5 of criteria that may affect the acceptance of an applicant to their residency programs. Average scores were calculated for each criterion. Results Of the 108 members invited to participate, only 12 (11.1% declined to participate. Interview performance was ranked as the most important criteria for selecting residents (average score: 4.63/5.00, followed by grade point average (average score: 3.78/5.00 and honors during medical school (average score: 3.67/5.00. On the other hand, receiving disciplinary action during medical school and failure in a required clerkship were considered as the most concerning among other criteria used to reject applicants (average scores: 3.83/5.00 and 3.54/5.00 respectively. Minor differences regarding the importance level of each criterion were noted across different programs. Conclusions This study provided general information about the criteria that are used to accept/reject applicants to residency programs in Kuwait. Future studies should be conducted to investigate each criterion individually, and to assess if these criteria are related to residents' success during their training.

Marwan Yousef

2013-01-01

 
 
 
 
341

Docking and scoring of metallo-beta-lactamases inhibitors  

DEFF Research Database (Denmark)

The performance of the AutoDock, GOLD and FlexX docking programs was evaluated for docking of dicarboxylic acid inhibitors into metallo-beta-lactamases (MBLs). GOLD provided the best overall performance, with RMSDs between experimental and docked structures of 1.8-2.6 A and a good correlation between the experimentally determined MBL-inhibitor affinities and the GOLD scores. GOLD was selected for a test including a broad spectrum of inhibitors for which experimental MBL-inhibitor binding affinities are available. This study revealed that (1) for most compound classes (dicarboxylic acids, tetrazoles, sulfonylhydrazones, and peptide-like compounds) there is a good correlation between the experimentally determined MBL-inhibitor affinities and the GOLD scores, (2) the correlation only holds within a given class, that is, scores of compounds from different classes cannot be directly compared, (3) for some compound classes (e.g. small sulphur compounds) there is no direct correlation between the experimentally determined MBL-inhibitor affinities and the GOLD scores. Using partial least squares methods, a model with R2 = 0.82 and Q2 = 0.78 for the training set was obtained based on the GOLD score and descriptors associated with binding of the IMP-1 inhibitors to the enzyme. The external Q2 for the test set is 0.73. This final model for prediction of IMP-1 MBL-inhibitor affinity handled all known classes of MBL-inhibitors, except small sulphur compounds.

Olsen, Lars; Pettersson, Ingrid

2004-01-01

342

RANKING CHEMISTRY JOURNALS USING THE HIRSCH INDEX AND ARTICLE INFLUENCE SCORE  

Directory of Open Access Journals (Sweden)

Full Text Available This study presents the Hirsch-index, impact factor and article influence score for the ranking of Chemistry journals. The study concludes that the Hirsch-index exhibits a good correlation with the influence score. A correlation of 60 Chemistry journals is analyzed.

SILVIU JIPA

2012-12-01

343

Overexpression of epidermal growth factor receptor as a prognostic factor in colorectal cancer on the basis of the Allred scoring system  

Science.gov (United States)

Background Overexpression of epidermal growth factor receptor (EGFR) is found in many types of neoplasms. The aim of the study was to evaluate EGFR expression in colorectal cancer (CRC) specimens and to determine whether EGFR expression correlates with clinicopathological data and overall survival. Patients and methods Tissue specimens from 181 consecutive CRC patients treated at the Military Institute of Medicine in 2006–2010 were collected and examined for EGFR expression, by immunohistochemistry staining. The staining intensity and percentage of cells with membranous EGFR expression were scored and then grouped according to the parameters of the Allred Scoring system. Cutoff values were subjected to further statistical analysis. Univariate tests and a multivariate Cox proportional hazards model were used in data analysis. Results EGFR was overexpressed in 96 of 181 CRC specimens (53%). EGFR expression was not correlated with other clinicopathological variables. On univariate analysis, overexpression of EGFR, determined by PS (percentage score) (>3) and total score (sum of PS and intensity score) (>4), was associated with poor overall survival. On multivariate analysis, EGFR overexpression (PS > 3) was an independent adverse prognostic factor (hazard ratio [HR] 1.62; 95% confidence interval [CI]: 1.03–2.53). Elevated carcinoembryonic antigen (CEA) serum concentration before treatment, performance status (Word Health Organization [WHO]-2), and tumor localized in colon and liver metastases were also independent unfavorable prognostic factors. Conclusion EGFR overexpression (PS > 3) in a CRC patient population was an independent adverse prognostic factor. Implementation of the Allred Scoring system criteria into clinical practice might facilitate treatment decisions in CRC patients. PMID:23926437

Rokita, Marta; Stec, Rafal; Bodnar, Lubomir; Charkiewicz, Radoslaw; Korniluk, Jan; Smoter, Marta; Cichowicz, Marzena; Chyczewski, Lech; Niklinski, Jacek; Kozlowski, Wojciech; Szczylik, Cezary

2013-01-01

344