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1

Citric acid etching of cervical sclerotic dentin lesions: an AFM study.  

Science.gov (United States)

Atomic force microscopy (AFM) has been used to determine microstructural changes, etching rates of peritubular dentin, and intertubular dentin recession during demineralization in dilute acidic solutions. These studies have not included many forms of altered dentin, including noncarious sclerotic root dentin associated with Cl V (abfraction) lesions. We sought to determine microstructural changes and recession rates during demineralization in citric acid (pH 2.5, 0.018M) for the transparent/sclerotic zone. Highly polished dentin disks were prepared from teeth with noncarious C1 V lesions (n = 3) and compared with normal root dentin (n = 3). Samples were etched at 5-s intervals for 1 min and at longer intervals up to 30 min. The depth changes in various portions of the dentin with respect to the reference layer were measured and changes in microstructure observed in solution in the wet cell of the AFM. In sclerotic dentin, most tubule lumens were occluded with crystalline deposits that etched more slowly than the other dentin components, but etching rates could not be determined due to their irregular geometry. The intertubular dentin recession quickly reached a plateau after a depth change of etching of sclerotic intertubular dentin and that of non-sclerotic root dentin that became apparent after 600 s (p = 0.037). The sclerotic intertubular dentin underwent less depth change at the plateau (558 nm) compared to normal root dentin (744 nm). In addition, normal root dentin underwent significantly greater recession than coronal dentin (p = 0.002). The results of this study indicate that intertubular sclerotic dentin from Cl V lesions etches differently than normal root dentin, and this may help explain the difficulties in restoring such lesions with current bonding procedures. PMID:10602066

Marshall, G W; Chang, Y J; Saeki, K; Gansky, S A; Marshall, S J

2000-03-01

2

Occult bony lesions associated with anterior cruciate ligament injury  

International Nuclear Information System (INIS)

To examine bony lesions associated with anterior cruciate ligament (ACL) injuries, magnetic resonance (MR) imaging was performed on 55 knees with ACL injuries. With respect to the period between ACL injuries and MR imaging, the knees were divided into acute (within one month), subacute (from one month to one year) and chronic (over one year) groups, containing 19, 16 and 20 knees, respectively. Occult bony lesions not shown in roentgenography were observed more frequently in the acute group (13/19) than in the other two groups (subacute group, 5/16; chronic group, 1/20), located in the lateral compartment of the knee joint. In the acute group, bony lesions had high signal intensity on T2-weighted images and low signal intensity on proton density images. In the subacute and chronic groups, bony lesions were less pronounced and had low signal intensity on T2-weighted images. These findings suggest that bony lesions are frequently associated with and occur simultaneously with ACL injury. (author)

1993-09-01

3

A solitary lesion of talus with mixed sclerotic and lytic changes: Rosai-Dorfman disease of 25 years' duration  

International Nuclear Information System (INIS)

Rosai-Dorfman disease (sinus histiocytosis with massive lymphadenopathy) is an unusual form of histiocytic disorder predominantly affecting children and young adults. Bone lesions are infrequent. We describe a 63-year-old woman with a solitary lesion of the talus which was misdiagnosed for 25 years. The patient never had adenopathy or other organ involvement. The radiographic findings were a mixture of sclerotic and lytic changes, an extremely rare and unusual presentation of the disease. (orig.)

2004-04-01

4

Injury of anterior cruciate ligament with associated bony lesions: MR image  

Energy Technology Data Exchange (ETDEWEB)

To evaluate the characteristic MR findings in injury of the anterior cruciate ligament (ACL) with associated bony lesions. We reviewed MR findings and the corresponding arthroscopic or operative results of 48 patients with ACL injuries, and evaluated ACL signal intensity and contour. In associated bony lesions, we determined the location of avulsion fracture and bony bruise. Complete ACL tears were seen in 27 cases, partial tears in 13, and avulsion injury in eight. Complete tears showed heterogeneously increased signal intensity with contour bulging in ten cases (37%), and combined bony lesion in 14 (52%). ACL with a thin continous low signal intensity band surrounding heterogeneously-increased signal intensity suggested partial tears, and was seen in three of 13 proven cases (23%) of partial ACL tears;combined bony lesion was seen in four such cases(31%). There were eight cases of avulsion fracture;the most frequent site was the anterolateral portion of the tibial spine (n=6). The most frequent sites of bony lesion were at the midportion of the lateral femoral condyle (n=6), and the posterior portion of the lateral tibial plateau (n=6);the next most frequent site was the anterior portion of the lateral tibial plateau (n=5). Tearing of the ACL was seen on MRI as ligament discontinuity, and heterogeneously increased signal intensity with ACL contour bulging. The most frequent sites of associated bony lesions were the midportion of the lateral femoral condyle, and the posterior portion of the lateral tibial plateau. In associated bony lesions, bony contusion suggested ACL tearing, but avulsion fracture suggested ligament avulsion injury without tear.

Kim, Soon; Oh, Yeon Hee; Lee, Chang Wook [Dongguk Univ. College of Medicine, Seoul (Korea, Republic of); Kim, Yong Min [Chungbuk Univ. College of Medicine, Chongju (Korea, Republic of); Lee, Hyeon Kyeong; Kim, Seung Hyeon; Lee, Sung Woo [Dongguk Univ. College of Medicine, Seoul (Korea, Republic of)

1997-05-01

5

Occult bony lesions associated with anterior cruciate ligament injury; Assessment with MR imaging  

Energy Technology Data Exchange (ETDEWEB)

To examine bony lesions associated with anterior cruciate ligament (ACL) injuries, magnetic resonance (MR) imaging was performed on 55 knees with ACL injuries. With respect to the period between ACL injuries and MR imaging, the knees were divided into acute (within one month), subacute (from one month to one year) and chronic (over one year) groups, containing 19, 16 and 20 knees, respectively. Occult bony lesions not shown in roentgenography were observed more frequently in the acute group (13/19) than in the other two groups (subacute group, 5/16; chronic group, 1/20), located in the lateral compartment of the knee joint. In the acute group, bony lesions had high signal intensity on T2-weighted images and low signal intensity on proton density images. In the subacute and chronic groups, bony lesions were less pronounced and had low signal intensity on T2-weighted images. These findings suggest that bony lesions are frequently associated with and occur simultaneously with ACL injury. (author).

Nawata, Koji; Toshima, Ryota; Yamamoto, Yoshizo (Tottori Univ., Yonago (Japan). School of Medicine); Suzuki, Toshiro; Date, Shinya

1993-09-01

6

The “Double-Pulley” Technique for Arthroscopic Fixation of Partial Articular-Side Bony Avulsion of the Supraspinatus Tendon: A Rare Case of Bony PASTA Lesion  

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We report the use of the double-pulley technique for arthroscopic fixation of the bony PASTA (partial articular surface tendon avulsion) lesion. Arthroscopic examination documented a 15-mm-long and 8-mm-wide comminuted bony avulsion with 2 main fragments. Two double-loaded suture anchors were placed with a transtendinous technique at the anterior and posterior edges of the lesion respecting the tendon insertion to the avulsed fragment. The medial sutures were retrieved through the intact supr...

Murena, Luigi; Canton, Gianluca; Falvo, Daniele A.; Genovese, Eugenio A.; Surace, Michele F.; Cherubino, Paolo

2013-01-01

7

A solitary lesion of talus with mixed sclerotic and lytic changes: Rosai-Dorfman disease of 25 years' duration  

Energy Technology Data Exchange (ETDEWEB)

Rosai-Dorfman disease (sinus histiocytosis with massive lymphadenopathy) is an unusual form of histiocytic disorder predominantly affecting children and young adults. Bone lesions are infrequent. We describe a 63-year-old woman with a solitary lesion of the talus which was misdiagnosed for 25 years. The patient never had adenopathy or other organ involvement. The radiographic findings were a mixture of sclerotic and lytic changes, an extremely rare and unusual presentation of the disease. (orig.)

Abdelwahab, Ibrahim Fikry [Department of Radiology, New York Methodist Hospital Affiliated with Weill Medical College of Cornell University, 506 Sixth Street, NY 11215, Brooklyn (United States); Klein, Michael J. [Department of Pathology, Mount Sinai Medical Center, 1 Gustave Levy Place, NY 10029, New York (United States); Springfield, Dempsey S. [Department of Orthopedics, Mount Sinai Medical Center, 1 Gustave Levy Place, NY 10029, New York (United States); Hermann, George [Department of Radiology, Mount Sinai Medical Center, 1 Gustave Levy Place, NY 10029, New York (United States)

2004-04-01

8

Percutaneous needle biopsy of bony lesions: diagnostic accuracy and clinical utility  

Energy Technology Data Exchange (ETDEWEB)

To evaluate the diagnostic accuracy and clinical utility of percutaneous needle biopsy of the bony lesions. Among 100 consecutive patients who underwent percutaneous needle biopsy of bony lesions, 96 patients who were diagnosed ultimately by surgery, or by clinical and radiological follow-up over 6 months were reviewed in this study. Biopsy sites were in the long bones in 51, axial bones in 45. Twelve biopsies were performed under CT guidance and the remainder were guided under fluoroscopy. The categories for the suspected diagnosis included 25 primary malignant tumors, 21 benign tumors, 31 metastases, 13 infections, and 6 miscellaneous lesions. Of the 96 biopsies, 86(89.6%) were adequate for the diagnosis out of which 81 were ultimately confirmed as true-positive or true-negative with the overall diagnostic accuracy rate of 94.2%. Diagnostic accuracy according to the suspected diagnosis was 91.3% in primary malignant tumors, 90.3% in metastases, and 100% in infections, benign tumors, and miscellaneous lesions. Respective diagnostic yield was 90.3% in metastases, 84.6% in infections, 84% in primary malignant tumors, 71.4% in benign tumors, and 100% in miscellaneous lesions. Both diagnostic accuracy and diagnostic yield differed little with the lesion location. No complication was observed in our series. Percutaneous needle biopsy of bony lesion is a safe procedure, offering high diagnostic accuracy and high clinical utility.

Jang, Hyun Jung; Kang, Heung Sik; Lee, Kyung Won; Kim, Jae Seung; Lee, Sang Hoon; Lee, Han Koo [Seoul National University College of Medicine, Seoul (Korea, Republic of)

1995-06-15

9

CT and MRI of intrinsic space-occupying lesions of the bony skull base  

International Nuclear Information System (INIS)

Intrinsic bony lesions of the skull base are diseases which arise within the bones forming the skull base. Mainly they are bone tumours and tumour-like lesions. With the exception of osteomas of the paranasal sinuses and exostoses of the external auditory canal, these lesions occur rarely. This article gives an overview of the appearance of the most common primary bony skull base masses in CT and MRI. From the authors' point of view these are fibrous dysplasia, chordomas, chondrosarcomas, Langerhans cell histiocytosis and multiple myelomas, which must be differentiated from pseudolesions. The possibilities of CT and MRI in making a specific diagnosis, differential diagnosis and the kind of making the final diagnosis are described. (orig.)

2009-07-01

10

Solitary sclerotic fibroma of the skin: a sclerotic dermatofibroma?  

Science.gov (United States)

Two cases of solitary tumors showing well-demarcated hypocellular, dermal fibrocollagenous proliferations are reported. The lesions were composed of hyalinized eosinophilic collagen bundles arranged in the characteristic interwoven pattern with prominent clefts, as described in sclerotic fibroma of the skin. This pattern, although predominant, was not uniform. Some areas showed a more cellular pattern with histopathologic features suggestive of dermatofibroma. In those areas, multiple spindle-shaped cells and occasional multinucleated cells were observed. The collagen bundles did not adopt a whorled pattern, and the overlying epidermis showed mild acanthosis and elongation of the rete ridges. The sclerotic changes were present mainly at the periphery and in the deep areas of the tumor. Our observations confirm the possibility that solitary sclerotic fibroma of the skin may represent, at least in some instances, the later and sclerotic stage of other more cellular neoplasms (specifically dermatofibromas) rather than an individualized neoplasm, as has been recently proposed. PMID:8989937

Pujol, R M; de Castro, F; Schroeter, A L; Su, W P

1996-12-01

11

Bizarre Parosteal Osteochondromatous Proliferation (Nora’s Lesion) of the Mandible. A Rare Bony Lesion  

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Bizarre parosteal osteochondromatous proliferation (BPOP) also eponymically called “Nora’s lesion”, is a rare benign reactive bone lesion first reported in 1983. BPOP occurs classically on the bones of the hands and feet and long bones. This lesion can easily be confused, both clinically and microscopically, with other benign and malignant lesions of bone, including osteochondroma, parosteal osteosarcoma, myositis ossificans and reactive periostitis. BPOP has been reported to have a hig...

Dashti, H. M.; Reith, J. D.; Schlott, B. J.; Lewis, E. L.; Cohen, D. M.; Bhattacharyya, I.

2012-01-01

12

The "Double-Pulley" Technique for Arthroscopic Fixation of Partial Articular-Side Bony Avulsion of the Supraspinatus Tendon: A Rare Case of Bony PASTA Lesion.  

Science.gov (United States)

We report the use of the double-pulley technique for arthroscopic fixation of the bony PASTA (partial articular surface tendon avulsion) lesion. Arthroscopic examination documented a 15-mm-long and 8-mm-wide comminuted bony avulsion with 2 main fragments. Two double-loaded suture anchors were placed with a transtendinous technique at the anterior and posterior edges of the lesion respecting the tendon insertion to the avulsed fragment. The medial sutures were retrieved through the intact supraspinatus tendon medially to the fracture. The sutures were initially coupled in a double-pulley configuration generating 2 sutures oriented from anterior to posterior; then a simple suture for each anchor oriented from medial to lateral was obtained. At the end of the procedure, the adequacy of reduction and stability of the fragments were confirmed. At 2 months from surgery, radiographic healing of the fracture was noted and integrity of the supraspinatus tendon insertion to the footprint was confirmed by arthro-magnetic resonance imaging, with full recovery of daily activities and complete active range of motion confirmed at 6 and 12 months. The double-pulley technique allows optimal reduction of bony fragments and reconstruction of normal footprint anatomy even in comminuted fractures. Moreover, it creates a waterproof reduction of the fragments, protecting the fracture site from synovial fluid. PMID:23767005

Murena, Luigi; Canton, Gianluca; Falvo, Daniele A; Genovese, Eugenio A; Surace, Michele F; Cherubino, Paolo

2013-02-01

13

Bizarre parosteal osteochondromatous proliferation (Nora's Lesion) of the mandible. a rare bony lesion.  

Science.gov (United States)

Bizarre parosteal osteochondromatous proliferation (BPOP) also eponymically called "Nora's lesion", is a rare benign reactive bone lesion first reported in 1983. BPOP occurs classically on the bones of the hands and feet and long bones. This lesion can easily be confused, both clinically and microscopically, with other benign and malignant lesions of bone, including osteochondroma, parosteal osteosarcoma, myositis ossificans and reactive periostitis. BPOP has been reported to have a high rate of recurrence. Only 3 cases of BPOP of the head and neck have been reported in the literature, of which one involved the maxilla. We present a rare case of BPOP involving the mandible in a 10 year old African American male. Microscopically, a fibro-cartilaginous cap giving rise to a proliferation of variably mineralized osteophytic finger-like projections of bone was seen. Multiple trabeculae of "blue bone" were noted as well as numerous atypical appearing chondrocytes. The lesion recurred within 4 months following the initial excision but has not recurred to date after the second local excision. To the best of our knowledge, this is the first report of BPOP arising in the mandible. In addition, we discuss the clinical and microscopic features, differential diagnosis, and prognosis of this rare entity. We present a case of BPOP of the mandible and believe this is the first report of such a case in the mandible. PMID:22094873

Dashti, H M; Reith, J D; Schlott, B J; Lewis, E L; Cohen, D M; Bhattacharyya, I

2012-06-01

14

Innumerable Small Bony Nodular Sclerotic Lesions with Negative Findings on Both Bone Scintigraphy and F-18 FDG PET: Osteopoikilosis a Patient of Breast Cancer  

International Nuclear Information System (INIS)

Osteopoikilosis is a rare, benign hereditary disease, which presents multiple osteosclerotic, and small round nodules in the bone. It is usually detected incidentally by radiological examination. A radionuclide bone scintigraphy is essential in distinguishing osteopoikilosis from osteoblastic metastases, because scintigraphic findings are usually normal in patients with osteopoikilosis. However, there have been no reports about F-18 fluorodeoxyglucose (FDG) PET findings in osteopoikilosis. Herein, we wish to report a case of osteopoikilosis with breast cancer, which could not be seen in either bone scintigraphy or F-18 FDG PET/CT

2008-06-01

15

Innumerable Small Bony Nodular Sclerotic Lesions with Negative Findings on Both Bone Scintigraphy and F-18 FDG PET: Osteopoikilosis a Patient of Breast Cancer  

Energy Technology Data Exchange (ETDEWEB)

Osteopoikilosis is a rare, benign hereditary disease, which presents multiple osteosclerotic, and small round nodules in the bone. It is usually detected incidentally by radiological examination. A radionuclide bone scintigraphy is essential in distinguishing osteopoikilosis from osteoblastic metastases, because scintigraphic findings are usually normal in patients with osteopoikilosis. However, there have been no reports about F-18 fluorodeoxyglucose (FDG) PET findings in osteopoikilosis. Herein, we wish to report a case of osteopoikilosis with breast cancer, which could not be seen in either bone scintigraphy or F-18 FDG PET/CT.

Jun, Sung Min; Kim, Yong Ki; Kim, In Ju; Nam, Hyun Yeol; Kim, Bum Soo [Pusan National University Hospital, Pusan (Korea, Republic of)

2008-06-15

16

Multifocal sclerotic BCG spondylitis in a 13-year-old girl  

Energy Technology Data Exchange (ETDEWEB)

A case is reported of multifocal BCG osteomyelitis in a 13-year-old girl. The lesions in the skull, ribs and in several vertebrae were mainly sclerotic and healed with antituberculotic therapy. The case is unusual because of the late onset, sclerotic changes, and involvement of the spine.

Sandstroem, S.

1983-06-01

17

CT and MRI of intrinsic space-occupying lesions of the bony skull base; CT und MRT bei intrinsischen raumfordernden Laesionen der knoechernen Schaedelbasis  

Energy Technology Data Exchange (ETDEWEB)

Intrinsic bony lesions of the skull base are diseases which arise within the bones forming the skull base. Mainly they are bone tumours and tumour-like lesions. With the exception of osteomas of the paranasal sinuses and exostoses of the external auditory canal, these lesions occur rarely. This article gives an overview of the appearance of the most common primary bony skull base masses in CT and MRI. From the authors' point of view these are fibrous dysplasia, chordomas, chondrosarcomas, Langerhans cell histiocytosis and multiple myelomas, which must be differentiated from pseudolesions. The possibilities of CT and MRI in making a specific diagnosis, differential diagnosis and the kind of making the final diagnosis are described. (orig.) [German] Unter intrinsischen Laesionen der knoechernen Schaedelbasis versteht man Erkrankungen, die von den die Schaedelbasis bildenden Knochen ausgehen. In erster Linie handelt es sich um Knochentumoren und tumoraehnliche Laesionen. Mit wenigen Ausnahmen (Nasennebenhoehlenosteome, Exostosen des aeusseren Gehoergangs) sind sie selten. Dieser Beitrag gibt einen Ueberblick ueber das CT- und MRT-Erscheinungsbild der aus Sicht der Autoren unter diesem Aspekt noch am haeufigsten anzutreffenden raumfordernden Laesionen. Dazu zaehlen die fibroese Dysplasie, Chordome, Chondrosarkome, die Langerhans-Zell-Histiozytose und das multiple Myelom. Abgrenzt werden muessen Pseudotumoren. Artdiagnostische Zuordnungsmoeglichkeiten durch CT und/oder MRT, Differenzialdiagnosen und Diagnosesicherung werden dargelegt. (orig.)

Koesling, S.; Brandt, S. [Martin-Luther-Universitaet Halle-Wittenberg, Universitaetsklinik und Poliklinik fuer Diagnostische Radiologie, Halle (Germany); Neumann, K. [Martin-Luther-Universitaet Halle-Wittenberg, Universitaetsklinik und Poliklinik fuer Hals-, Nasen-, Ohrenheilkunde, Kopf- und Halschirurgie, Halle (Germany)

2009-07-15

18

Destructive lesion of vertebral body: CT findings and differential diagnosis of inflammation and malignancy  

International Nuclear Information System (INIS)

The CT findings and their differential points were evaluated by reviewing the CT scans of 47 patients with destructive lesions of vertebral bodies which included tuberculous spondylitis(23), pyogenic infection(9), syphilitic spondylitis(1) and malignant lesion(14). Twenty-one (91.3%) of 23 patients with tuberculous spondylitis showed mixed osteolytic and osteosclerotic patterns of bony destruction. Six(66.7%) of 9 patients with pyogenic infection and 10(71.4%) of 14 malignant lesions showed osteolytic pattern of bony destruction. Thrity(90.9%) of 33 infectious lesions including pyogenic infection and tuberculous spondylitis involved intervertebral disc, while the involvement of intervertebral disc was not found in malignant lesion. The Swiss cheese appearance of bony destruction was commonly seen in tuberculous spondylitis, but pyogenic infections and malignant lesions more commonly revealed geographic or moth-eaten appearance. The sequestral pattern and sclerotic rims in and around bony destruction were mainly seen in tuberculous spondylitis, and they were thought to be specific findings in tuberculous spondylitis. CT of the spine appears to offer the detailed findings of vertebral body destruction and may be a useful adjunct in differentiation between tuberculous spondylitis, pyogenic infections and malignant lesions of the spine

1993-09-01

19

ORV Arthroscopic Transosseous Bony Bankart Repair  

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The arthroscopic treatment of the “bony Bankart lesion” continues to evolve. We present a novel technique that we developed at Orthopaedic Research of Virginia, the “transosseous bony Bankart repair,” which incorporates several essential concepts to provide for optimal healing and rehabilitation. We promote arthroscopic repair emphasizing bone preservation, a fracture interface without interposing sutures, the ability to reduce capsular volume, and multiple points of stable glenolabra...

Myer, Daniel M.; Caldwell, Paul E.

2012-01-01

20

Bony sequestrum: A radiologic review  

Energy Technology Data Exchange (ETDEWEB)

According to a pathological definition, a bony sequestrum is defined as a piece of devitalized bone that has been separated from the surrounding bone during the process of necrosis. However, the radiological definition of a sequestrum is different and refers to an image of calcification visible within a lucent lesion, completely separated from the surrounding bone, without referring to the vascular status and histological nature of the calcified tissue. The term ''button sequestrum'' has been used in calvarial lesions. The prototype conditions that may present with a bony sequestrum are osteomyelitis and skeletal tuberculosis. Other conditions such as radiation necrosis, eosinophilic granuloma, metastatic carcinoma, primary lymphoma of bone, aggressive fibrous tumors may also manifest as osteolytic lesions containing a sequestrum. In addition, some primary bone tumors produce a matrix that may mineralize and sometimes simulate a bone sequestrum. These include osteoid tumors (osteoid osteoma, osteoblastoma), cartilaginous tumors (chondroma and chondroblastoma), lipomatous tumors (lipoma), and benign fibrous tumors (fibromyxoma, myxoma, and desmoplastic fibroma). Therefore, various conditions may present at imaging as a small area of osteolysis containing central calcifications. However, a careful analysis of the sequestrum as well as the associated clinical and radiological findings often enables to point toward a limited number of conditions. (orig.)

Jennin, Felicie; Bousson, Valerie; Parlier, Caroline; Jomaah, Nabil; Khanine, Vanessa; Laredo, Jean-Denis [Lariboisiere Hospital, Department of Radiology, Paris (France)

2011-08-15

 
 
 
 
21

Bony sequestrum: A radiologic review  

International Nuclear Information System (INIS)

According to a pathological definition, a bony sequestrum is defined as a piece of devitalized bone that has been separated from the surrounding bone during the process of necrosis. However, the radiological definition of a sequestrum is different and refers to an image of calcification visible within a lucent lesion, completely separated from the surrounding bone, without referring to the vascular status and histological nature of the calcified tissue. The term ''button sequestrum'' has been used in calvarial lesions. The prototype conditions that may present with a bony sequestrum are osteomyelitis and skeletal tuberculosis. Other conditions such as radiation necrosis, eosinophilic granuloma, metastatic carcinoma, primary lymphoma of bone, aggressive fibrous tumors may also manifest as osteolytic lesions containing a sequestrum. In addition, some primary bone tumors produce a matrix that may mineralize and sometimes simulate a bone sequestrum. These include osteoid tumors (osteoid osteoma, osteoblastoma), cartilaginous tumors (chondroma and chondroblastoma), lipomatous tumors (lipoma), and benign fibrous tumors (fibromyxoma, myxoma, and desmoplastic fibroma). Therefore, various conditions may present at imaging as a small area of osteolysis containing central calcifications. However, a careful analysis of the sequestrum as well as the associated clinical and radiological findings often enables to point toward a limited number of conditions. (orig.)

2011-08-01

22

Surgical Management of Myxoma Like Sclerotic Calcified Mass in Left Ventricle Outflow Tract  

Directory of Open Access Journals (Sweden)

Full Text Available In this short report, we present the succesfull surgical traetment of a patient who had an echocardiographic diagnosis of left ventricular mass during her routine controls. This patient was treated by surgical excision of the ventricular mass and after the pathological examination the diagnosis was “myxoma like sclerotic calcified mass”. The postoperative course was uneventful, and the patient was discharged on day 7 of surgery. The follow-up period lasted for 2 years without any event and the echocardiograms revelaed no residual or reccurrent lesions. Surgical resection of intracardiac masses are necessary and safe treatment options but there is not a standardization about the type of surgical options. The localization of the mass has the key role in determining the type of the surgical approach. In this case, aortotomy provided a good access and facilitated the exposure of this rare myxoma like sclerotic calcified mass.

Banu Bilezikçi

2011-04-01

23

Detection of sclerotic bone metastases in the spine using watershed algorithm and graph cut  

Science.gov (United States)

The early detection of bone metastases is important for determining the prognosis and treatment of a patient. We developed a CAD system which detects sclerotic bone metastases in the spine on CT images. After the spine is segmented from the image, a watershed algorithm detects lesion candidates. The over-segmentation problem of the watershed algorithm is addressed by the novel incorporation of a graph-cuts driven merger. 30 quantitative features for each detection are computed to train a support vector machine (SVM) classifier. The classifier was trained on 12 clinical cases and tested on 10 independent clinical cases. Ground truth lesions were manually segmented by an expert. The system prior to classification detected 87% (72/83) of the manually segmented lesions with volume greater than 300 mm3. On the independent test set, the sensitivity was 71.2% (95% confidence interval (63.1%, 77.3%)) with 8.8 false positives per case.

Wiese, Tatjana; Yao, Jianhua; Burns, Joseph E.; Summers, Ronald M.

2012-02-01

24

T-tube insertion for sclerotic subglottic stenosis.  

Science.gov (United States)

T-tube insertion is effective treatment for subglottic stenosis, but it is generally difficult due to bending of the T-tube. In a 52-year-old woman with relapsing polychondritis, a T-tube was inserted after predilatation using Hegar dilators. We describe the details of our T-tube insertion methods for sclerotic subglottic stenosis. PMID:24585799

Goto, Taichiro; Kato, Ryoichi

2014-02-01

25

The sclerotic pedicle - how many causes are there?  

International Nuclear Information System (INIS)

The sclerotic pedicle is a commonly encountered roentgen sign that may be associated with numerous conditions, both benign and malignant. The following paper discusses the common as well as the unusual causes of this interesting phenomenon and demonstrates the radiographic presentations of the various etiologies. (orig.)

1990-01-01

26

Radiographic evaluation of therapeutic response in bony metastases of breast cancer  

International Nuclear Information System (INIS)

Response to chemotherapy was evaluated in 50 previously untreated patients with bony metastases of breast cancer. Lytic metstates respond in a definite sequence: sclerotic rim, filling-in, uniformly blastic, uniform fading. Increase in size of lytic areas or destruction in previously responding areas signals worsening. Mixed metastases are considered as beginning with a sclerotic rim. Response is otherwise similar. Particular attention is paid to the lytic areas. Blastic metastases are considered as beginning at the uniformly blastic stage. Progression is marked by a volumetric increase in blastic change or destruction in blastic regions. Change occurs slowly. Review of multiple studies is often necessary to reach the correct conclusion and clinical history is necessary. (orig.)

1981-01-01

27

Dopamine-Mediated Sclerotization of Regenerated Chitin in Ionic Liquid  

Directory of Open Access Journals (Sweden)

Full Text Available Chitin is a promising structural material for biomedical applications, due to its many advantageous properties and abundance in nature. However, its usage and development in the biomedical field have been stagnant, because of chitin’s poor mechanical properties in wet conditions and the difficulties in transforming it into an applicable form. To overcome these challenges, we created a novel biomimetic chitin composite. This regenerated chitin, prepared with ionic liquid, showed improved mechanical properties in wet conditions by mimicking insect cuticle and squid beak sclerotization, i.e., catechol-meditated cross-linking. By ionic liquid-based heat treatment, dopamine oxidation produced melanin-like compounds and dopamine-meditated cross-links without any solvent evaporation and oxidant utilization. The dopamine-meditated sclerotization increased the ultimate tensile strength (UTS of the regenerated chitin by 2.52-fold, measured after six weeks of phosphate-buffered saline (PBS submersion. In addition, the linear swelling ratio (LSR of the chitin film was reduced by about 22%. This strategy raises a possibility of using regenerated chitin as an artificial hard tissue in wet conditions.

Dongyeop X. Oh

2013-09-01

28

Bony Calvarium as the Sole Site ofMetastases in Squamous Cell Carcinomaof the Uterine Cervix  

Directory of Open Access Journals (Sweden)

Full Text Available Isolated skeletal metastasis to the bony calvarium is extremely rare in patients with squamous cell carcinoma of the uterine cervix. We describe the clinical and imaging findings in a case of squamous cell carcinoma of the uterine cervix with metastases tothe bony calvarium as the sole site of metastasis. The patient was a 65-year-old woman with squamous cell carcinoma of the uterine cervix, FIGO stage IIIb, whose initial treatement was chemoradiation therapy. After 22 sessions of external-beam radiation,she developed headaches. On physical examination she had skull bone tenderness. On plain skull X-ray, there were osteolytic bony lesions. Brain MRI showed multiple enhancing skull bone metatstses. Eventually, a whole body bone scintigraphy revealed isolated diffuse increased activity in the bony calvarium. In the literature review, wefound only three similar cases of cervical cancer with scalp metastases and involvement of the bony calvarium.

Mohammad Mohammadianpanah

2010-10-01

29

Bony ankylosis following thermal and electrical injury  

Energy Technology Data Exchange (ETDEWEB)

Objective. Bony ankylosis has been described following trauma, paralysis, psoriasis, Reiter's syndrome, ankylosing spondylitis, juvenile chronic arthritis and rheumatoid arthritis. Reports of bony ankylosis following thermal and electrical injury are limited.Design and patients. Thirteen cases of burn-related joint ankylosis in four patients are presented.Conclusion. Patients with burns from thermal or electrical injury may develop bony ankylosis among other radiographic manifestations. This bony ankylosis may result either from bridging extra-articular heterotopic ossification with preservation of the underlying joint or from intra-articular fusion due to joint destruction. (orig.)

Balen, P.F.; Helms, C.A. [Dept. of Radiology, Duke University Medical Center, Durham, NC (United States)

2001-07-01

30

Bony ankylosis of temporomandibular joint  

International Nuclear Information System (INIS)

Ankylosis of joint is defined as limited movement due to infection, trauma, or surgical procedure. A 59-year-old female with a chief complaint of limited movements during mouth opening had a positive history of trauma to her right TMJ area about 5 years ago. From that time, progressive mouth opening limitation and intermittent pain have occurred. At the time of admission the patient showed mandibular deviation to the right side during mouth opening, with a maximum opening limited to 5 mm. On plain radiographs, right condylar enlargement and joint space reduction by newly formed bony tissues were observed. CT scans showed right condylar enlargement, cortical sclerosis, and thickening of the condyle, articular fossa and articular eminence.

2002-06-01

31

Bony ankylosis of temporomandibular joint  

Energy Technology Data Exchange (ETDEWEB)

Ankylosis of joint is defined as limited movement due to infection, trauma, or surgical procedure. A 59-year-old female with a chief complaint of limited movements during mouth opening had a positive history of trauma to her right TMJ area about 5 years ago. From that time, progressive mouth opening limitation and intermittent pain have occurred. At the time of admission the patient showed mandibular deviation to the right side during mouth opening, with a maximum opening limited to 5 mm. On plain radiographs, right condylar enlargement and joint space reduction by newly formed bony tissues were observed. CT scans showed right condylar enlargement, cortical sclerosis, and thickening of the condyle, articular fossa and articular eminence.

Lee, Byeong Do; Yoon, Young Nam; Um, Ki Doo; Ra, Jong Ill; Lee, Wan [School of Dentistry, Wonkwang University, Iksan (Korea, Republic of)

2002-06-15

32

Post Pelvic Radiotherapy Bony Changes  

Energy Technology Data Exchange (ETDEWEB)

There has been recent interest in radiation-induced bone injury in clinical conditions, especially for pelvic insufficiency fracture (PIF). A PIF is caused by the effect of normal or physiological stress on bone with demineralization and decreased elastic resistance. Pelvic radiotherapy (RT) can also contribute to the development of a PIF. A PIF has been regarded as a rare complication with the use of megavoltage equipment. However, recent studies have reported the incidence of PIFs as 8.2{approx}20% after pelvic RT in gynecological patients, an incidence that was higher than previously believed. The importance of understanding a PIF lies in the potential for misdiagnosis as a bony metastasis. If patients complain of pelvic pain after whole-pelvis radiation therapy, the presence of a PIF must be considered in the differential diagnosis. The use of multibeam arrangements and conformal RT to reduce the volume and dose of irradiated pelvic bone can be helpful to minimize the risk of fracture. In addition to a PIF, osteonecrosis and avascular necrosis of the femoral head can develop after radiation therapy. Osteoradionecrosis of the pelvic bone is a clinical diagnostic challenge that must be differentiated from an osseous metastasis. A post-radiation bone sarcoma can result as a long-term sequela of pelvic irradiation for uterine cervical cancer.

Huh, Seung Jae [Samsung Medical Center, Seoul (Korea, Republic of)

2009-03-15

33

Multiple supernumerary teeth associated with bony malformations.  

Science.gov (United States)

Full blown cases of cleidocranial dysplasia (CCD) have been reported earlier but a case with a rarity of 60 teeth associated with bony malformations, is seldom observed Because of the oral findings this condition has been diagnosed at an early age, thus helping to achieve a better oral harmony. This article reports an atypical case with 16 supernumerary teeth associated with bony malformations. PMID:22524086

Kamatham, R; Sharada, J; Mohapatra, A; Nuvvula, S

2011-01-01

34

Bony spurs projecting in the obturator foramen.  

Science.gov (United States)

The obturator foramen is large oval aperture in males or irregularly triangular aperture in females in the hipbone, situated anteroinferior to the acetabulum between the pubis and ischium. The dry bone under study is a male left sided hipbone. It contains the obturator groove through which the obturator nerve and vessels pass. During analysis of hipbones in the osteology laboratory of CSM Medical University Lucknow, UP, India, a hipbone was found in which bony spurs or exostoses were projecting from the margins into the obturator foramen. These bony projections in the obturator foramen constitute a new anatomical variant in the hipbone, as they have not been reported before. These bony spurs may impinge on the obturator nerve and vessels causing neurovascular complications and also trauma to the soft tissues during biomechanical movements. In addition, these bony spurs may cause spasms of the obturator internus and externus muscles, causing groin pain. These bony projections may also lead to misinterpretation of radiographs. Thus, knowledge of these bony spurs is of paramount importance to anatomists, surgeons, sport physicians, and radiologists. PMID:22648594

Singh, R

2012-05-01

35

Contraction gap versus shear bond strength of dentin adhesive in sound and sclerotic dentins.  

Science.gov (United States)

To evaluate the effect of a dentin adhesive on sclerotic dentin, contraction gap width and shear bond strength were measured. Dentin cavity wall was pretreated with an experimental dentin bonding system with and without a dentin primer, or with a commercial dentin bonding system. In the experimental dentin bonding groups, contraction gap width of sclerotic dentin was significantly smaller than that of sound dentin when the cavity was not primed with glyceryl monomethacrylate. For each individual tooth, the correlation between contraction gap width and shear bond strength was insignificant. In conclusion, the bonding efficacy of dentin bonding systems to sclerotic dentin was superior to that of sound dentin. Further, it was determined that it was impossible to detect the interaction between the polymerization contraction stress of resin composites and the efficacy of dentin adhesives by measuring bond strength. PMID:17076330

Kusunoki, Mizuho; Itoh, Kazuo; Takahashi, Yoichi; Hisamitsu, Hisashi

2006-09-01

36

Quantification of sclerotic renal glomeruli during the aging process in humans  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction. The aim of our research was to quantify the presence of totally sclerotized glomeruli during the aging process. Material and Methods. The study material were kidney tissue samples taken from fiftysix cadavers, their age ranging from 20 to over 70 years. They were classified in six age groups: I (20-29, II (30-39, III (40-49; IV (50-59; V (60-69 and VI (older than 70. The tissue samples were routinely histologically processed and then cut into the slices 5 mm thick, which were then stained and stereologically analyzed under the microscope with a projection screen (Reichert Visopan with 10 x lens magnification and multipurpose test system M42 application. The analysis was carried out on 20 fields of vision per one sample. The numerical density of completely sclerotic and other glomeruli was measured, and the resulting percentages were obtained from this parameter. Results. Completely sclerotic glomeruli were not found in the first group. They were observed in the II aging group (5% for the first time. Their numerical density and percentage increased during the aging process and was 18% in the IV, 25% in the V and maximally 37.5% in the VI aging group. Conclusion. Finally, the above cited results pointed to the increase of completely sclerotized and the decreased presence of normal glomeruli during the aging process

Pavlovi? Snežana

2010-01-01

37

Bony island within the articular cartilage of the knee in a child: a rare condition for early osteoarthritis  

Directory of Open Access Journals (Sweden)

Full Text Available Articular cartilage is a specific type of connective tissue composed of hydrated proteoglycans within a matrix of collagen fibrils. In the elderly population, it shows degenerative changes that may results in osteoarthritis. The more severe form of osteoarthritis occasionally demonstrates bone formation within the cartilage, which is designated as a bony protuberance, however, such lesions are rare in children. This report presents the case of a 10-year-old boy with a bony protuberance within the articular cartilage of the knee. The patient initially complained of knee pain and he subsequently developed flexion contracture. Radiological and arthroscopic examinations revealed a bony protuberance in the articular cartilage and degenerative changes of the cartilage above it. He was successfully treated by the removal of the bony protuberance and osteochondral grafting. The bony protuberance may have caused cartilage degradation since the thickness of the cartilage above it was thinner than that around the lesion. The bony protuberance within the articular cartilage formed in the younger population may be a possible cause of osteoarthritis. This case is a noteworthy with regard to the pathogenesis of osteoarthritis.

Eiji Itoi

2011-03-01

38

Ultrasound of the elbow: A systematic approach using bony landmarks  

International Nuclear Information System (INIS)

The use of bony landmarks can be helpful in performing an ultrasound study of the elbow. We discuss bony landmarks that can be used for evaluation of the common extensor tendon, ulnar collateral ligament and common flexor tendon, coronoid and olecranon fossa, ulnar nerve, and biceps tendon. We discuss bony landmarks for each of these structures.

2012-05-01

39

Micromorphological and hardness analyses of human and bovine sclerotic dentin: a comparative study  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The purpose of this study was to test the hypothesis that both human and bovine sclerotic dentin have similar hardness properties, in addition to similar micromorphological characteristics. Sixteen teeth (8 human and 8 bovine) exhibiting exposed dentin in the incisal edge and showing characteristics typical of sclerosis were used. Vickers surface microhardness testing was conducted. Three areas of the dentin surface of each specimen were selected. All teeth were processed for scanning electro...

Gisela Muassab Castanho; Márcia Martins Marques; Juliana Barbosa Marques; Maitê André Camargo; Antonio Alberto de Cara

2011-01-01

40

Effects of Altered Catecholamine Metabolism on Pigmentation and Physical Properties of Sclerotized Regions in the Silkworm Melanism Mutant  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Catecholamine metabolism plays an important role in the determination of insect body color and cuticle sclerotization. To date, limited research has focused on these processes in silkworm. In the current study, we analyzed the interactions between catecholamines and melanin genes and their effects on the pigmentation patterns and physical properties of sclerotized regions in silkworm, using the melanic mutant melanism (mln) silkworm strain as a model. Injection of ?-alanine into mln mutant s...

Qiao, Liang; Li, Yuanhao; Xiong, Gao; Liu, Xiaofan; He, Songzhen; Tong, Xiaoling; Wu, Songyuan; Hu, Hai; Wang, Rixin; Hu, Hongwei; Chen, Lushi; Zhang, Li; Wu, Jie; Dai, Fangyin; Lu, Cheng

2012-01-01

 
 
 
 
41

Advances in genomics of bony fish.  

Science.gov (United States)

In this review, we present an overview of the recent advances of genomic technologies applied to studies of fish species belonging to the superclass of Osteichthyes (bony fish) with a major emphasis on the infraclass of Teleostei, also called teleosts. This superclass that represents more than 50% of all known vertebrate species has gained considerable attention from genome researchers in the last decade. We discuss many examples that demonstrate that this highly deserved attention is currently leading to new opportunities for answering important biological questions on gene function and evolutionary processes. In addition to giving an overview of the technologies that have been applied for studying various fish species we put the recent advances in genome research on the model species zebrafish and medaka in the context of its impact for studies of all fish of the superclass of Osteichthyes. We thereby want to illustrate how the combined value of research on model species together with a broad angle perspective on all bony fish species will have a huge impact on research in all fields of fundamental science and will speed up applications in many societally important areas such as the development of new medicines, toxicology test systems, environmental sensing systems and sustainable aquaculture strategies. PMID:24291769

Spaink, Herman P; Jansen, Hans J; Dirks, Ron P

2014-03-01

42

Bony structure suppression in chest radiographs  

DEFF Research Database (Denmark)

Many computer aided diagnosis schemes in chest radiography start with preprocessing steps that try to remove or suppress normal anatomical structures from the image. Examples of normal structures in posteroanterior chest radiographs are bony structures. Removing these kinds of structures can be done quite effectively if the right dual energy imagesâ??two radiographic images from the same patient taken with different energiesâ??are available. Subtracting these two radiographs gives a soft-tissue image with most of the rib and other bony structures removed. In general, however, dual energy images are not readily available. We propose a supervised learning technique for inferring a soft-tissue image from a standard radiograph without explicitly determining the additional dual energy image. The procedure, called dual energy faking, is based on k-nearest neighbor regression, and incorporates knowledge obtained from a training set of dual energy radiographs with their corresponding subtraction images for the construction of a soft-tissue image from a previously unseen single standard chest image.

Loog, Marco; van Ginneken, Bram

2006-01-01

43

Computed tomography findings of bony regeneration after radiotherapy for nasopharyngeal carcinoma with skull base destruction: implications for local control  

International Nuclear Information System (INIS)

Purpose: To evaluate the response of bony destruction (BD) of the skull base following radiotherapy in nasopharyngeal carcinoma (NPC) and investigate the implications of bony regeneration (BR) on local control and its related factors. Methods and Materials: Ninety patients with NPC with skull base destruction clearly demonstrated on computed tomography (CT) were reviewed. These patients have completed the prescribed treatment and received regular CT follow-up. A total of 338 sets of CT images of the head and neck were reviewed. The tumor response and the appearance of BR in the previous destructive part of the skull base were recorded and analyzed. The tumor response was divided into complete, partial, or no response. BR was defined as recalcification or sclerotic change with partial or complete healing in the previous osteolytic bony defect. Local failure was confirmed either by pathological or merely by imaging studies showing progression of tumor in consecutive radiological pictures. Results: The distribution of specific sites of bony destruction (BD) in these patients included the sphenoid bone (68%), paracavernous sinus area (48%), petrous apex (47%), clivus (44%), pterygoid plates (20%), and others (7%). The CT showed 57 patients (63%) had BR. All were observed within 1 year after treatment. Sixty-two patients (69%) had complete tumor response after treatment. Analyzed by logistic regression method, tumor response after treatment was found to have a statistically significant correlation with BR (p = 0.0004). Most BR (55/57) was demonstrated in patients with complete tumor response. The 3-year actuarial local control rate was 54 % in these patients. The local control was quite different in the comparison of patients with BR versus those with persistent BD (77% vs. 21%, p < 0.0001). Multivariate analysis showed that patients with complete tumor response or with BR on imaging had statistically better local control than those without either of the two findings (p < 0.05). Conclusion: Appearance of BR at previous destructive skull base following radiotherapy for NPC patients could be clearly demonstrated on CT. Bony regeneration significantly correlated with treatment response and local control. Although the underlying significance of BR was unknown, to predict the outcome after treatment, the appearance of BR shown on CT may imply the complete eradication of tumor in this area

1999-05-01

44

Incidental bony pathology when reporting trauma orthopantomograms  

Energy Technology Data Exchange (ETDEWEB)

Radiologists frequently report orthopantomograms (OPTs) and other views of the mandible, most often in patients who have suffered facial trauma. These examinations may reveal incidental pathology. It is important that radiologists are aware of the radiological appearances and the clinical significance of these lesions. In this review we will present examples of the more common odontogenic lesions including: radicular cyst, odontogenic keratocyst, dentigerous cyst, ameloblastoma, and also examples of non-odontogenic pathology: bisphosphonate-related osteonecrosis of the jaw (BRONJ) and chronic osteomyelitis. Although some of the lesions will require computed tomography (CT) or magnetic resonance imaging (MRI) for further lesion characterization and evaluation of the surrounding tissues, we are going to focus on the plain film appearances. We will also briefly discuss the pathogenesis, epidemiology, and treatment of these lesions.

Macanovic, M., E-mail: mladenmaca@gmail.co [Derriford Hospital NHS Trust, Plymouth (United Kingdom); Gangidi, S.; Porter, G.; Brown, S.; Courtney, D. [Derriford Hospital NHS Trust, Plymouth (United Kingdom); Porter, J. [Community Dental Service, Plymouth Primary Care Trust, Plymouth, Devon (United Kingdom)

2010-10-15

45

Congenital bony fusion (absence) of the knee: a case report.  

Science.gov (United States)

Congenital knee ankylosis is a rare condition which might be accompanied with other abnormalities or not. To our knowledge, there is no report on true bony ankylosis of the knee. The only ones in the literature include fibrous knee ankylosis. Thus this seems to be the first presentation of true congenital bony fusion of the knee joint. PMID:20061155

Madadi, F; Kahlaee, A H; Sarmadi, A; Madadi, Fi; Sadeghian, R; Emami, T M M; Abbasian, M R

2010-12-01

46

Subperiostial and intracortical aneurysmal bony cyst - Cases report  

International Nuclear Information System (INIS)

The aneurismal bony cyst is a benign bony tumor that is presented in the second decade of the life; it commits the bones around the knee, later elements of the column and flue proximal. It diagnoses it is clinical and radiological; it confirms by means of biopsy that should discard concomitant malignancy. This tumor can have an aggressive behavior for what is important to give him a meticulous treatment with resection, curettage and bony implant. The radiotherapy has very precise indications and it should not be used of routine by the malignancies risk. Their prognostic it is quite good

2003-12-01

47

CT-guided once-through bilateral percutaneous needle puncturing sclerotic therapy for bilateral multiple renal cysts: preliminary results  

International Nuclear Information System (INIS)

Objective: To evaluate CT-guided once-through bilateral percutaneous needle puncturing, aspiration and injection of sclerotic agents (ethanol) in treating bilateral multiple renal cysts. Methods: CT-guided once-through bilateral percutaneous needle puncturing sclerotic therapy was performed in 19 patients with bilateral multiple renal cysts. First, under CT guidance the puncture points and puncture routs were decided, then, puncturing, aspiration, rinsing and ethanol injection of the cysts were taken place by turn. The clinical results were analyzed. Results: bilateral percutaneous needle puncturing sclerotic therapy was successfully completed in all 19 cases. The whole procedure was well tolerated by all patients. The mean operative time was 23 minutes with a range of 20-35 minutes. No severe complications occurred. Conclusion: With proficient manipulation, CT-guided bilateral percutaneous needle puncturing sclerotic therapy for bilateral multiple renal cysts can be smoothly carried out. The technique can reduced the number of sclerotherapy times, cut down the medical expenses and, therefore, get twofold results with half the effort. (authors)

2011-06-01

48

Direct bony invasion of malignant melanoma  

Directory of Open Access Journals (Sweden)

Full Text Available Malignant melanoma is known to spread by local extention, by the lymphatics by the blood stream. Direct invasion of the bone from a cutaneous melanoma is unknown. Hence, this case is presented in view of its rarity. A 75-year-old Caucasian lady presented with a small papillary lesion in the region of a recurrent chronic cellulitis on the lower third of the lateral aspect of the right leg. Histopathology diagnosed the lesion as locally advanced malignant melanoma. Radiological investigations by X-ray and magnetic resonance imaging revealed malignant infiltration of the tibia in its mid and lower third with two soft tissue metastatic masses adjacent. Histology following amputation confirmed malignant melanoma with cranial resection margin involvement. She underwent a further above-knee amputation followed by chemotherapy. The patient recovered from the amputation but subsequently died 6 months later due to bronchopneumonia from lung metastasis.

Mula Viswanath

2009-01-01

49

Rosai-Dorfman Disease: Report of a Case Associated with IgG4-Related Sclerotic Lesions  

Science.gov (United States)

We describe a rare case of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) associated with a six-year history of autoimmune pancreatitis, which was controlled by steroid treatment. The patient presented with multiple, cervical and thoracic lymphadenopathy and abnormal, nodular opacities in the lung. Histologically, Rosai-Dorfman disease with numerous IgG4-positive cells was identified in a subcutaneous lymph node in the patient's left forearm. The patient recovered uneventfully with steroid treatment.

Park, Bong-Hee; Son, Da Hye; Kim, Myung-Hwan; Shim, Tae Sun; Lee, Hee Jin

2012-01-01

50

Rosai-Dorfman Disease: Report of a Case Associated with IgG4-Related Sclerotic Lesions  

Digital Repository Infrastructure Vision for European Research (DRIVER)

We describe a rare case of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) associated with a six-year history of autoimmune pancreatitis, which was controlled by steroid treatment. The patient presented with multiple, cervical and thoracic lymphadenopathy and abnormal, nodular opacities in the lung. Histologically, Rosai-Dorfman disease with numerous IgG4-positive cells was identified in a subcutaneous lymph node in the patient's left forearm. The patient recovered un...

Park, Bong-hee; Son, Da Hye; Kim, Myung-hwan; Shim, Tae Sun; Lee, Hee Jin; Huh, Jooryung

2012-01-01

51

The detection of sclerotic changes of the coronaries and heart valves by scanning beams (ultrafast computed tomography using EVOLUTION)  

International Nuclear Information System (INIS)

With the advent of ultrafast computed tomography the range of diagnostic procedures for the quantitative determination of pathological changes in the coronary arteries has been broadened. The calcified coronary plaques found in this study, which in some of the patients were markedly pronounced, gave no immediate clue as to what extent sclerotic changes had already occurred in the coronaries examined. Nor was it possible on the basis of this method to pinpoint the vascular sections showing calcified plaques in patients undergoing maintenance dialysis. It may, however, permit careful predictions to be made for patients at a high risk of developing coronary artery disease. Sclerotic changes of the heart values occur with above-average frequency in dialysis patients and may be assessed quantitatively by the method described. The results described show that findings revealed by scanning electron beams may provide indirect information on metabolic processes in patients suffering from chronic ailments. (orig./MG)

1994-02-01

52

[Bony avulsions of the rotator cuff : Arthroscopic concepts].  

Science.gov (United States)

Bony avulsions of the rotator cuff and isolated greater or lesser tuberosity fractures are rare injuries and a clear consensus regarding classification and therapy does not yet exist. Conservative therapy is limited, especially in injuries with displaced fragments and in these cases surgical treatment is frequently indicated. The ongoing development of arthroscopic techniques has led to quite a number of reports about arthroscopically assisted or total arthroscopic techniques in the treatment of these injuries. The advantages and disadvantages of arthroscopic concepts for the treatment of bony avulsions of the rotator cuff are presented with reference to the current literature. PMID:21153534

Greiner, S; Scheibel, M

2011-01-01

53

Association between the proportion of globally sclerotic glomeruli and various morphologic variables and clinical data of IgA nephropathy patients  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction: Immunoglobulin A nephropathy is the most common form of glomerular nephropathy among children and young adults.Objectives: To evaluate the possible correlation between the extent of sclerotic glomeruli and various morphologic variables and clinical data of IgA nephropathy (IgAN patients, we conducted an observational study, on 136 IgAN patients’ biopsies.Patients and Methods: Of the 136 patients, 94 (69.1% were male. The mean age of the patients was 37.6 ± 13.4 years. The mean of serum creatinine was 1.94±3.7 mg/dl (median=1.2mg/dl, also mean of proteinuria was 1726±1247 mg/day (median=1500 mg/day. In this study of 14.9±3.7 glomeruli in biopsies, 2.5±3.2 (median=2 were globally sclerotic.Results: In this study we found, significant positive correlation between proportion of globally sclerotic glomeruli and serum creatinine, amount of proteinuria, and also quantity of tubulointerstitial fibrosis. Also, in this study, the association of proportion of globally sclerotic glomeruli with M, E, S and T variables of Oxford classification was significantly positive.Conclusion: We propose firstly that, sclerotic glomeruli reported routinely in the pathology reports of IgA nephropathy patients and secondly we suggest further investigations to possible inclusion of other morphologic variables like proportion of sclerotic glomeruli to Oxford classification of IgAN to widen the scope of this classification.

Nasri Hamid

2012-12-01

54

Supernumerary Bones in the Walls of the Bony Orbit  

Directory of Open Access Journals (Sweden)

Full Text Available Occurrence of supernumerary bones in the walls of the orbit especially in the medial wall and the roof has beendescribed in the literature. Studies of the prevalence of supernumerary bones in the bony wall of the orbit are scarce in theliterature. Present study was undertaken to find the prevalence of supernumerary bones in the walls of the orbit in acollection of adult Indian skulls.In the present study three hundred and twenty six orbital walls from one hundred and sixty three skulls wereexamined for the presence of the sutural bones. Their location with reference to the sutures in the walls of the orbit andtheir size was noted. The supernumerary bones were found in 25 skulls (15.34 % mainly in the lateral wall (11.04 % and theroof of the orbit (4.29 %. Prevalence of such supernumerary bones in the walls of the bony orbit is of anthropologicalinterest. Many of the bony ossicles were of sufficiently large size, enough to be visualized on lateral skull X-ray and couldeasily be mistaken for fracture of the bony wall of the orbit.

K.Y. Manjunath

2013-01-01

55

First Trimester Abortion: A Rare Cause of Intrauterine Bony Spicules  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Bony fragments in the uterus occur after second trimester termination of pregnancy following retained fetal bones. Very rarely, they can form following first trimester loss. Clinical symptoms range from pain, menstrual symptoms, and infertility. Ultrasound shows a hyperechoic shadow, and treatment is by curettage or hysteroscopic removal.

Singla, Anshuja; Gupta, Bindiya; Guleria, Kiran

2012-01-01

56

Bone density three-dimensional CT of skull base lesions. Simultaneous use of multiplanar reconstruction  

Energy Technology Data Exchange (ETDEWEB)

We performed bone density three-dimensional CT (3D-CT) of six skull base lesions. Multiplanar reconstruction (MPR) was also performed in 5 cases. The ability to demonstrate the lesions on 3D-CT was examined in addition to additional information of MPR. 3D-CT clearly demonstrated the bony lesions in 5 cases. In one case, the internal architecture of the lesion was visualized with cutting procedure. In all, minute bony change and adjacent soft tissue lesion were observed at any plane on MPR. Simultaneous use of 3D-CT and MPR may be useful for demonstrating skull base lesions. (author)

Suzuki, Masayuki; Takashima, Tsutomu; Ueda, Fumiaki [Kanazawa Univ. (Japan). School of Medicine] [and others

1998-04-01

57

Unusual cause of generalized osteolytic vertebral lesions: a case report  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Abstract Background Vertebral sarcoidosis is an extremely rare form of osseous sarcoidosis. Although osseous sarcoidosis is almost always an incidental finding of sarcoidosis elsewhere in the body, vertebrae may be the primary disease site. Involvement of vertebrae is usually localized and sclerotic or lytic. Case presentation We describe a case of extensive asymptomatic vertebral involvement by sarcoid with osteolytic lesions. Making the diagnosis requires biop...

Nanda Sudip; Bhatt Surya; Steinberg David; Volk Stephen A

2007-01-01

58

La displasia cemento ósea florida y su diagnóstico diferencial The Florid cemento-bony dysplasia and the differential diagnosis  

Directory of Open Access Journals (Sweden)

Full Text Available Las lesiones benignas fibro-óseas de los maxilares constituyen un grupo diverso de enfermedades con una característica histológica común: la sustitución de hueso normal por tejido compuesto de colágeno y fibroblastos, con cantidades variables de una sustancia mineral que puede ser de hueso, cemento o ambos. Estas lesiones incluyen la displasia fibrosa, la displasia cemento-ósea en sus variantes: periapical, focal o florida, el cementoma gigantiforme familiar y el fibroma osificante cemento-osificante. La osteomielitis es un proceso inflamatorio agudo o crónico de los espacios medulares o corticales del hueso, que se extiende más allá del sitio inicial de desenvolvimiento. La osteomielitis esclerosante difusa es más frecuente en adultos, principalmente en la mandíbula. Se presenta radiográficamente como una lesión radiopaca difusa adyacente a los dientes, que puede ser multifocal. El objetivo de este trabajo fue describir un caso inusual de lesión fibro-ósea, cuyo diagnóstico diferencial se hizo también con la osteomielitis de los maxilares. Se concluyó que las lesiones fibro-óseas benignas, presentaron muchas similitudes con respecto a sus aspectos clínicos, radiográficos e histológicos. Por lo tanto, es fundamental el análisis conjunto de estas informaciones para obtener un diagnóstico definitivo.The benign fibrous-bony lesions are a diverse group of diseases with common features: replacement of normal bone by tissue composed of collagen and fibroblasts, with variable amounts of a mineral substance that could be bone, cement or both. These lesions include the fibrous dysplasia, the periapical cement-bony dysplasia, focal or florid, familiar giant cementoma and ossifying fibroma (cement-ossifying. Osteomyelitis is an acute or chronic inflammatory process of medullar or cortical spaces of bone extending beyond the onset site of development. Diffuse sclerosing osteomyelitis involves to adults mainly the mandible and radiographically is a diffuse radiopaque lesion adjacent to teeth and could be multifocal. The aim of present paper is to describe an uncommon case of fibrous-bony lesion also diagnosed with maxillary osteomyelitis. We conclude that the above mentioned lesions are very similar regarding its clinical, radiographic and histological features. Thus, it is fundamental the combined analysis of these informations to obtain a definite diagnosis.

Allan Ulisses Carvalho de Melo

2011-09-01

59

Imaging of the hip and bony pelvis. Techniques and applications  

International Nuclear Information System (INIS)

This is a comprehensive textbook on imaging of the bony pelvis and hip joint that provides a detailed description of the techniques and imaging findings relevant to this complex anatomical region. In the first part of the book, the various techniques and procedures employed for imaging the pelvis and hip are discussed in detail. The second part of the book documents the application of these techniques to the diverse clinical problems and diseases encountered. Among the many topics addressed are congenital and developmental disorders including developmental dysplasia of the hip, irritable hip and septic arthritis, Perthes' disease and avascular necrosis, slipped upper femoral epiphysis, bony and soft tissue trauma, arthritis, tumours and hip prostheses. Each chapter is written by an acknowledged expert in the field, and a wealth of illustrative material is included. This book will be of great value to musculoskeletal and general radiologists, orthopaedic surgeons and rheumatologists. (orig.)

2006-01-01

60

Percutaneous embolization of bony pelvic neoplasms with tissue adhesive  

International Nuclear Information System (INIS)

Eight patients with tumors of the bony pelvis underwent embolization with isobutyl-2-cyanoacrylate (IBCA). Five patients had primary bone tumors, of which 2 were malignant and 3 were benign; 3 patients had metastases to the bony pelvis from the thyroid gland, kidney, and femur, respectively. Embolization was performed to minimize blood loss during resection of a giant-cell tumor in one patient and insertion of a hip prosthesis in another who had metastatic renal carcinoma. It was also done prior to scheduled surgery in one of the patients with aneurysmal bone cyst, but healing was sufficient to cancel the operation; in the other patient, embolization was the only therapy. Palliative embolization was performed in 4 patients with malignant tumors after other means failed to control pain or slow progression. IBCA appears to be an efficient means of occluding the vessels feeding selected primary bone tumors and metastases

1983-01-01

 
 
 
 
61

Percutaneous embolization of bony pelvic neoplasms with tissue adhesive.  

Science.gov (United States)

Eight patients with tumors of the bony pelvis underwent embolization with isobutyl-2-cyanoacrylate (IBCA). Five patients had primary bone tumors, of which 2 were malignant and 3 were benign; 3 patients had metastases to the bony pelvis from the thyroid gland, kidney, and femur, respectively. Embolization was performed to minimize blood loss during resection of a giant-cell tumor in one patient and insertion of a hip prosthesis in another who had metastatic renal carcinoma. It was also done prior to scheduled surgery in one of the patients with aneurysmal bone cyst, but healing was sufficient to cancel the operation; in the other patient, embolization was the only therapy. Palliative embolization was performed in 4 patients with malignant tumors after other means failed to control pain or slow progression. IBCA appears to be an efficient means of occluding the vessels feeding selected primary bone tumors and metastases. PMID:6187041

Keller, F S; Rösch, J; Bird, C B

1983-04-01

62

Percutaneous embolization of bony pelvic neoplasms with tissue adhesive  

Energy Technology Data Exchange (ETDEWEB)

Eight patients with tumors of the bony pelvis underwent embolization with isobutyl-2-cyanoacrylate (IBCA). Five patients had primary bone tumors, of which 2 were malignant and 3 were benign; 3 patients had metastases to the bony pelvis from the thyroid gland, kidney, and femur, respectively. Embolization was performed to minimize blood loss during resection of a giant-cell tumor in one patient and insertion of a hip prosthesis in another who had metastatic renal carcinoma. It was also done prior to scheduled surgery in one of the patients with aneurysmal bone cyst, but healing was sufficient to cancel the operation; in the other patient, embolization was the only therapy. Palliative embolization was performed in 4 patients with malignant tumors after other means failed to control pain or slow progression. IBCA appears to be an efficient means of occluding the vessels feeding selected primary bone tumors and metastases.

Keller, F.S.; Rosch, J.; Bird, C.B.

1983-04-01

63

CT of cholesteatomas - In respect to bony complications  

International Nuclear Information System (INIS)

We retrospectively analyzed twenty-eight cases of surgically confirmed cholesteatoma with CT putting emphasis on the following items: (1) location and extent of cholesteatoma: (2) erosion of scutum and lateral attic wall; (3) erosion of ossicles; (4) erosion of the bony labyrinth; (5) erosion of the facial nerve canal (6) erosion of the tegmen; (7) erosion of the sigmoid sinus; (8) erosion of the bony external auditory canal; and (9) intracranial complications. CT correctly predicted extent of 16 cases among surgically well documented 23 cholesteatomas. It was difficult to differentiate cholesteatoma from granulation tissue. Erosion of the scutum and/or lateral attic wall was seen in 16 cases (57%). The diagnostic accuracy of CT in the evaluation of the status of the ossicles was 92% (22/24). The most commonly involved portion of the ossicles was the long process of incus. There were seven cases having erosion of the bony labyrinth. Lateral semicircular canal was exclusively eroded. Coronal CT depicted erosion of lateral semicircular canal more accurately. Facial nerve canal erosion was found in six cases (21%). Eroded portion was distal limb of the first genu and mastoid segment each in three cases. Erosion of tegmen and sigmoid sinus plate was identified in four (14%) and six cases(21%), respectively. There were three cases of intracranial complication, manifest as lateral sinus thrombosis in two cases and epidural abscess in one case. All these three cases had erosion of the sigmoid sinus plate. We experienced three cases of 'automastoidectomy' and two cases of 'impending automastoidectomy'. In both of these two conditions, the patterns of erosion of EAC were very similar. The only difference was that whether the spontaneous drainage of cholesteatomatous mass had occurred or not yet. At the end of this issue, we briefly comment the CT findings of recurrent cholesteatoma we experienced in three cases. We believe high- resolution CT is a very reliable method and should be the first step in the evaluation of cholesteatoma

1990-12-01

64

Bony variations on coronary CT cuts of the paranasal sinuses  

International Nuclear Information System (INIS)

Bony variations in the anterior ethmoids may, if severe, play an important role in the development of chronic sinusitis and present the surgeon with added risks during operation. We have, therefore, analysed 390 preoperative CT examinations of the sinuses performed in the coronary plane with respect to the frequency of bone variations. Concha bullosa, increased pneumatisation of the agger nasi, large ethmoidal bullae, Haller's cells and increased pneumatisation of the sphenoid were found with equal frequency in about 20%. The most common variants occurred in the uncinate process (31.5%), less common were paradoxical curve of the middle turbinates (13.3%) and very rare were Onodi cells (1.3%). (orig.)

1993-12-01

65

Computed tomography in bony stenosis of the cervical spinal canal  

International Nuclear Information System (INIS)

This communication summarizes the author's attempts at evaluation of the cervical spinal canal in cases of localized or generalized spinal stenosis with computed tomography. As the scanner used neither had a tiltable gantry nor a scanogram facility he was forced to develop means to correctly position patients and localize scan levels. CT appears well suited for the evaluation of the dimensions of the cervical spinal canal, although meticulous positioning is of the utmost importance. It is often also the radiographic method which provides the most important diagnostic information in the various disease entities causing bony stenosis of the cervical spinal canal. (Auth.)

1979-09-08

66

MRI findings of cyclops lesions of the knee  

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Cyclops lesions develop in the anterior aspect of the intercondylar notch typically after anterior cruciate ligament (ACL) reconstruction or injury. It is a lesion consisting of fibrous tissue with or without cartilage and bony components. A cyclops lesion is one of the causes for reduced extension and, in the cases reported here, also knee pain or discomfort after ACL reconstruction. We present the MRI features, particularly the features on proton density weighted turbo spin echo...

Minne, Cornelia; Velleman, Mark D.; Suleman, Farhana Ebrahim

2012-01-01

67

A case report of odontogenic myxoma with characteristic multilocular lesion  

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Although odontogenic myxoma (OM) has various radiographic appearances, the characteristic features of OM are the multilocular radiolucent lesion, straight bony septa along the margin forming either square or triangular spaces. We present a case of OM in a 25-year old-male patient. Multilocular radiolucent lesion on the left mandible body showed tennis racket appearance. Cone beam computed tomography (CBCT) showed straight bony septa along the margin and cortical perforation. This CBCT features would have significantly contributed to allowing a diagnosis of OM. We think that this case shows characteristic radiographic features of odontogenic myxoma.

Lee, Byung Do; Lee, Wan; Paeng, Jun Young [Department of Oral and Maxillofacial Radiology, School of Dentistry, Wonkwang University, Iksan (Korea, Republic of); Son, Hyun Jin [Department of Pathology, Eulji University School of Medicine, Daejeon (Korea, Republic of)

2009-03-15

68

A case report of odontogenic myxoma with characteristic multilocular lesion  

International Nuclear Information System (INIS)

Although odontogenic myxoma (OM) has various radiographic appearances, the characteristic features of OM are the multilocular radiolucent lesion, straight bony septa along the margin forming either square or triangular spaces. We present a case of OM in a 25-year old-male patient. Multilocular radiolucent lesion on the left mandible body showed tennis racket appearance. Cone beam computed tomography (CBCT) showed straight bony septa along the margin and cortical perforation. This CBCT features would have significantly contributed to allowing a diagnosis of OM. We think that this case shows characteristic radiographic features of odontogenic myxoma.

2009-03-01

69

Lifa Disease: Frictional Dermal Melanosis over Bony Prominences (Clinicopathological Study  

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Full Text Available Background: Lifa disease (Frictional dermal melanosis over bony prominences has been described in Iraq for the first time in 1993, as a new distinctive pigmentary skin condition that followed chronic friction with a body washing agent (lifa during bathing. Objective: To assess this increasingly common problem where still many doctors unaware about its presence especially in other Middle East countries. Patients and Methods: A case series descriptive study done in Departments of Dermatology-Najaf and Baghdad Teaching Hospitals, between March 2007- Oct.2008. Full history and clinical examination were done for all patients including Wood's light examination. Biopsies were taken from 21 patients and sent for hematoxylin-eosin and Congo red stains. Results: Fifty two (49 female and 3 male patients with typical clinical features of lifa disease were studied. The mean age of presentation was 27.92 ± 7.58 years. All patients were slim with prominent bones and low body mass index, used lifa vigorously during bathing.Pigmentation was distributed bilaterally and symmetrically over bony prominences. The most common affected sites were: clavicular areas (67.3% and upper back (42%. Wood's light and histopathological examinations revealed dermal melanosis. No amyloid deposit was detected by using Congo red stain in any patient. Conclusions: Lifa disease is a common distinctive pigmentary disfiguring problem especially among females. The histopathology showed dermal melanosis, and might be confused with other pigmentary problems like macular amyloidosis.

Khalifa E. Sharquie

2012-09-01

70

Correlations between activity of tartrate-resistant acid phosphatase-5b and whole body bone scan in patients of breast cancer with bony metastases  

International Nuclear Information System (INIS)

Objective: Tartrate-resistant acid phosphatase 5b (TRAP-5b) is a novel marker for evaluating osteoclastic activity and rate of bone resorption. The study observed the changes of circulating TRAP-5b activity and findings of bone scans in breast cancer patients with suspicious bony metastases. Methods: A total of 34 breast cancer patients with suspicious bony metastases were studied. Blood sampling and Tc-99m MDP (20mCi) whole body scans were performed at the same time. Specimens were stored at -70 and were simultaneously analyzed for activity of circulating TRAP-5b using a home-made EIA method (normal reference value: 3) groups. Results: Six patients revealed limited lesions (LL) and the other 28 revealed extended lesions (EL). Of the 34 patients, 20 received repeated bone scans which showed 7 in regression and 13 in progression of the bony lesions after anti-cancer treatment. The activity of TRAP-5b decreased significantly in regression group (mean±SD, 4.05±0.81 vs. 2.36±0.88 U/L; P<0.01) but not changed apparently in progression group (5.39±2.37 vs. 5.58±2.08 U/L). The TRAP-5b activity, however, significantly correlated with NL seen on bone scan (r= 0.52, P<0.01). Conclusion: TRAP-5b might be a suitable marker to evaluate status of bony metastases in patients with breast cancer and might also provide a reference to therapeutic response in this patient group

2002-09-01

71

CT of cholesteatomas - In respect to bony complications  

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We retrospectively analyzed twenty-eight cases of surgically confirmed cholesteatoma with CT putting emphasis on the following items: (1) location and extent of cholesteatoma: (2) erosion of scutum and lateral attic wall; (3) erosion of ossicles; (4) erosion of the bony labyrinth; (5) erosion of the facial nerve canal (6) erosion of the tegmen; (7) erosion of the sigmoid sinus; (8) erosion of the bony external auditory canal; and (9) intracranial complications. CT correctly predicted extent of 16 cases among surgically well documented 23 cholesteatomas. It was difficult to differentiate cholesteatoma from granulation tissue. Erosion of the scutum and/or lateral attic wall was seen in 16 cases (57%). The diagnostic accuracy of CT in the evaluation of the status of the ossicles was 92% (22/24). The most commonly involved portion of the ossicles was the long process of incus. There were seven cases having erosion of the bony labyrinth. Lateral semicircular canal was exclusively eroded. Coronal CT depicted erosion of lateral semicircular canal more accurately. Facial nerve canal erosion was found in six cases (21%). Eroded portion was distal limb of the first genu and mastoid segment each in three cases. Erosion of tegmen and sigmoid sinus plate was identified in four (14%) and six cases(21%), respectively. There were three cases of intracranial complication, manifest as lateral sinus thrombosis in two cases and epidural abscess in one case. All these three cases had erosion of the sigmoid sinus plate. We experienced three cases of 'automastoidectomy' and two cases of 'impending automastoidectomy'. In both of these two conditions, the patterns of erosion of EAC were very similar. The only difference was that whether the spontaneous drainage of cholesteatomatous mass had occurred or not yet. At the end of this issue, we briefly comment the CT findings of recurrent cholesteatoma we experienced in three cases. We believe high- resolution CT is a very reliable method and should be the first step in the evaluation of cholesteatoma.

Kim, Hyung Jin; Chung, Hae Gyeong; Gong, Jae Chul; Jeon, Sea Young; Lim, Byeong Hoon; Kim, Jae Hyoung; Do, Young Soo; Chung, Sung Hoon [Gyeong Sang National University College of Medicine, Chinju (Korea, Republic of); Shin, Si Ok [Chungbuk National University College of Medicine, Chungju (Korea, Republic of)

1990-12-15

72

A case with the bilateral narrow bony cochlear nerve canals associated with near normal hearing thresholds.  

Science.gov (United States)

The narrow bony cochlear nerve canal in high resolution temporal bone computed tomography is frequently found in patients of congenital sensorineural hearing loss. But this bony structural anomaly could not conclude the functional outcome of cochlear nerve. Here, we present a case of a 14-month-old girl having bilateral narrow bony cochlear nerve canals. In magnetic resonance imaging, both the cochlear nerves were identified to be intact. Moreover, acoustic brainstem response threshold and auditory steady state response revealed nearly normal hearing thresholds. Therefore, we suggest that the narrow bony cochlear nerve canal itself does not necessarily indicate a substantial degree of hearing loss. PMID:24653890

Ahn, Jae-Cheul; Kim, Shin-Hye; Choi, Byung Yoon

2012-12-01

73

The skull base: tumoral lesions  

International Nuclear Information System (INIS)

Many lesions occur in the anterior, central and posterior skull base. In order to detect and characterise them, one has to apply the best imaging technique. Today MR is the preferred technique, and the use of CT is more and more restricted to evaluate the presence of calcifications and involvement of thin bony walls, foramina and fissures. However, MR is only superior when the right sequences and imaging planes are used. Many lesions can be characterised by their specific signal intensity on different sequences and by their location. Nevertheless some lesions can only be characterised after biopsy. The purpose of imaging in skull base tumours remains in the first place the evaluation of the exact tumour extent, and this is again best achieved with MR. In this paper the imaging technique and the most frequent skull base tumours are discussed. (orig.)

2005-03-01

74

Surfers ankle: a bony spur of the talar neck.  

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A 27-year-old competitive surfer presented with a history of a painful right ankle. He was able to recall an injury to his right ankle 4-5 years previously, sustained while surfing. The mechanism described was that he had dropped a considerable height during take-off, sustaining an impact injury from the board. He recalled immediate pain and swelling followed by 2-3 weeks of pain and a limp; he continued to surf, albeit with difficulty, despite this.Investigations found him to have a bony spur on the anterolateral part of the talus. This case shows how this injury is similar to those observed in other sports. PMID:21709829

Brooks, Francis Michael; Williams, Paul; Carpenter, E C

2009-01-01

75

Imaging pattern of calvarial lesions in adults  

International Nuclear Information System (INIS)

Calvarial lesions often present themselves as clinically silent findings on skull radiographs or as palpable masses that may cause localized pain or soreness. This review aims to explore the radiographic, computed tomography (CT), and magnetic resonance imaging (MRI) characteristics of calvarial neoplastic, inflammatory, and congenital lesions that are common in adults in order to facilitate a structured approach to their diagnosis and limit the differential diagnosis. In addition to reviewing the literature, we reviewed the records of 141 patients of the Montreal Neurological Institute and Hospital with radiologically documented calvarial lesions between 2001 and June 2009. CT is ideal for detecting bony lesions and is helpful in precisely localizing a lesion pre-surgically. MRI is best at identifying intradiploic lesions before they affect the cortical tables and is able to establish extraosseous involvement, especially when paramagnetic contrast is employed. (orig.)

2011-10-01

76

Ultrasonographic appearance of bony abnormalities at the dorsal aspect of the fetlock joint in geriatric cadaver horses.  

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This article describes the ultrasonographic (US) appearance of bony abnormalities on the dorsal aspect of the third metacarpal/metatarsal bone of the equine fetlock in cadavers with radiographic signs of osteoarthrosis. After US, computed tomography was undertaken to better characterise the lesions. Twelve fetlock joints were collected and all had more than one bone abnormality on US. Normal subchondral bone appeared on US as a well-defined and regular hyperechoic line with distal acoustic shadowing. Bone abnormalities detected on US included (1) gaps in the proximal subchondral bone filled with material of heterogeneous echogenicity, (2) bone fragments represented as small straight smoothly delineated hyperechoic lines with distal shadowing located superficial to the surface of the adjacent bone, (3) proximal new bone formation visible as mild to severe cortical protrusions, (4) marginal osteophytoses seen as an elevation of the hyperechoic surface of the subchondral bone at the edges of the joint surfaces, (5) indentations in subchondral bone seen as a concave deviation of the hyperechoic line without interruption, (6) focal or diffuse irregularities of the subchondral bone seen as disruptions of the normal smooth bony contours, and (7) focal hyperechoic spikes originating from the subchondral plate and invading the articular cartilage. These findings are discussed. PMID:22078389

Vanderperren, K; Gielen, I; Van Caelenberg, A; Van der Vekens, E; Raes, E V; Hauspie, S; van Bree, H; Saunders, J H

2012-07-01

77

Study on morphology of subacromial bony spur using three-dimensional computed tomography  

International Nuclear Information System (INIS)

Arthroscopic subacromial decompression (ASD) is a procedure required for rotator cuff tears and impingement syndrome, but the amount of bone to be removed and range of decompression depend on the surgery performed. We reviewed the morphology of bony spur using three-dimensional computed tomography (3DCT). The subjects were 27 cases operated on for rotator cuff tears from October 2008 to July 2009. We took CT images of all cases preoperatively. We classified the morphology of bony spurs into four groups according to size and investigated the characteristics. The bony spur was found to elongate to the coracoid process and show double floor-like configuration inwards. Moreover, when the bony spur size increases, the duration of the disease also increases. In addition, there was a tendency for the size of rotator cuff tears to grow large except in trauma cases. 3DCT can capture the morphological characteristics of subacromial bony spurs and provide useful information in ASD. (author)

2010-09-01

78

Focal hand lesions: review and radiological approach.  

Science.gov (United States)

Focal hand lesions are commonly encountered in clinical practice and are often benign. Magnetic resonance (MR) imaging is the imaging modality of choice in evaluating these lesions as it can accurately determine the nature of the lesion, enhancement pattern and exact location in relation to surrounding tissues. However, while MR features of various soft tissue lesions in the hand have been well described, it is often still difficult to differentiate between benign and malignant lesions. We review the MR imaging features of a variety of focal hand lesions presenting at our institution and propose a classification into "benign", "intermediate grade" (histologically benign but locally aggressive with potential for recurrence) and frankly "malignant" lesions based on MR findings. This aims to narrow down differential diagnoses and helps in further management of the lesion, preoperative planning and, in cases of primary malignancy, local staging. Teaching Points • Hand lesions are often benign and MR is essential as part of the workup. • MR features of various hand lesions are well described but are often non-specific. • Certain MR features may help for the diagnosis but histological examination is usually required. • We aim to classify hand lesions based on MR features such as margin, enhancement and bony involvement. • Classifying these lesions can help narrow down differential diagnoses and aid management. PMID:24838840

Lee, Chau Hung; Tandon, Ankit

2014-06-01

79

Effect of the application time of phosphoric acid and self-etch adhesive systems to sclerotic dentin  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in english Objective: To evaluate the effect of application time on the resin-dentin bond strength (µTBS) and etching pattern of adhesive systems applied on sclerotic dentine. Material and Methods: A total of forty-two bovine incisors had their roots removed. The 1-step self-etc [...] h GO (SDI), the 2-step self-etch Adper SE Bond (3MESPE) and the 35% phosphoric acid (3MESPE) from the 2-step etch-and-rinse Adper Single Bond 2 (3MESPE) were applied on the bovine incisal surfaces according to the manufacturer's instructions or duplicating the recommended conditioning time. After adhesive application, thirty teeth were restored with composite resin, stored for 24 h in distilled water at 37°C, and sectioned into resin-dentin bonded sticks (0.8 mm 2 ) and tested according to the µTBS at 0.5 mm/min. The etching pattern of the remaining twelve teeth (n=4 for each material) was examined under scanning electron microscopy. Each tooth was divided into a buccal-to-lingual direction into three thirds, and each third randomly assigned to the groups: control (no treatment), according to the manufacturers' instructions and duplicating the recommended application time. The µTBS and the relative percentage of the tubule area opening were evaluated by two-way repeated measures ANOVA and Tukey's tests (?=0.05). Results: The duplication of the conditioning time favored only the GO adhesive (p

Alexandra Patricia, Mena-Serrano; Eugenio Jose, Garcia; Miguel Muñoz, Perez; Gislaine Cristine, Martins; Rosa Helena Miranda, Grande; Alessandro Dourado, Loguercio; Alessandra, Reis.

80

Effect of the application time of phosphoric acid and self-etch adhesive systems to sclerotic dentin  

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Full Text Available Objective: To evaluate the effect of application time on the resin-dentin bond strength (µTBS and etching pattern of adhesive systems applied on sclerotic dentine. Material and Methods: A total of forty-two bovine incisors had their roots removed. The 1-step self-etch GO (SDI, the 2-step self-etch Adper SE Bond (3MESPE and the 35% phosphoric acid (3MESPE from the 2-step etch-and-rinse Adper Single Bond 2 (3MESPE were applied on the bovine incisal surfaces according to the manufacturer's instructions or duplicating the recommended conditioning time. After adhesive application, thirty teeth were restored with composite resin, stored for 24 h in distilled water at 37°C, and sectioned into resin-dentin bonded sticks (0.8 mm 2 and tested according to the µTBS at 0.5 mm/min. The etching pattern of the remaining twelve teeth (n=4 for each material was examined under scanning electron microscopy. Each tooth was divided into a buccal-to-lingual direction into three thirds, and each third randomly assigned to the groups: control (no treatment, according to the manufacturers' instructions and duplicating the recommended application time. The µTBS and the relative percentage of the tubule area opening were evaluated by two-way repeated measures ANOVA and Tukey's tests (?=0.05. Results: The duplication of the conditioning time favored only the GO adhesive (p<0.05. Both application methods significantly increased the tubule area opening (p<0.05 compared to the controls. Conclusions: The efficacy of duplicating the conditioning time was only effective for the 1-step self-etch adhesive system tested.

Alexandra Patricia Mena-Serrano

2013-04-01

 
 
 
 
81

STUDY ABOUT INCIDENCE OF CONGENITAL BONY ABNORMALITIES IN A POPULATION WITH MENTAL DEFICIENCY  

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Full Text Available This study is about the incidence of congenital bony abnormalities in a population with mental deficiency. Is known that genetic disorders cause mental disorders and malformative disorders, including bony abnormalities. The most often observed congenital abnormalities are:congenital hip sprain, flat foot, club foot, equin foot and congenital vertebral column disorders. We studied 596 children interned in in Neurology and Psychiatry Clinical Hospital of Oradea between 1999 and 2001 period. In 596 children, 393 presented different types of mental deficiency. We observed that most common bony disorders in this population are congenital hip sprain, vertebral column abnormalities and club foot.

Ioana Mihaela Tomulescu

2003-01-01

82

CT image evaluation of the internal rotation limit prior to bony impingement after total hip arthroplasty  

International Nuclear Information System (INIS)

This study evaluated the internal rotation limit prior to bony impingement of the proximal femur on the pelvis after total hip arthroplasty (THA). Reconstructed computed tomography (CT) images of 90 deg hip flexion were used to simulate the internal rotation limit against safety limits measured intraoperatively. Ninety joints in 86 subjects (12 men and 74 women) underwent THA for the treatment of secondary coxarthrosis. The correlation between the internal rotation limit prior to the bony impingement intraoperatively and the simulated internal rotation angle on the reconstructed CT image was statistically significant. We provide a new method to simulate the internal rotation limit prior to bony impingement based on postoperative CT. (author)

2002-01-01

83

Algodystrophy in children and young adults with isotopic bony hypofixation. A propos of 5 observations  

International Nuclear Information System (INIS)

The authors report 5 observations of young adults 3 teen-agers and 2 children suffering from algodystrophy, and in whom isotopic exploration of the skeleton disclosed a clear bony hypofixation during the entire evolution. These observations confirm their 1981 work concerning a young adult suffering from algodystrophy with isotopic bony hypofixation. Recent Canadian and American studies emphasize also the frequency of isotopic hypofixation in children algodystrophy. It seems, therefore, that isotopic bony hypofixation (linked perhaps to a decreased blood flow), is rather specific of algodystrophy in young subjects

1986-01-01

84

The paediatric wrist revisited - findings of bony depressions in healthy children on radiographs compared to MRI  

International Nuclear Information System (INIS)

The presence of erosions is used for diagnosis and monitoring of disease activity in juvenile idiopathic arthritis (JIA). Assessment of carpal bone erosions in children is challenging due to lack of normal references. To define normal appearances of bony depressions in the wrist on radiographs and MRI. MRI and radiography of the wrist were performed in 88 healthy children, 5-15 years of age. We assessed the number of bony depressions within the carpals/proximal metacarpals on both modalities, separately and combined. A total of 75 carpal depressions were identified on radiography compared to 715 on MRI. The number of bony depressions identified radiographically showed no statistically significant difference across age-groups. Within the metacarpals, there was no significant difference between bony depressions identified by MRI or radiography, except at the bases of the second metacarpal. Bony depressions that resemble erosions are normal findings in the wrist in children. MRI identifies more depressions than radiographs in the carpus. Some bony depressions occur at typical locations and should be accounted for when assessing the wrist in JIA to avoid overstaging. (orig.)

2012-07-01

85

The paediatric wrist revisited - findings of bony depressions in healthy children on radiographs compared to MRI  

Energy Technology Data Exchange (ETDEWEB)

The presence of erosions is used for diagnosis and monitoring of disease activity in juvenile idiopathic arthritis (JIA). Assessment of carpal bone erosions in children is challenging due to lack of normal references. To define normal appearances of bony depressions in the wrist on radiographs and MRI. MRI and radiography of the wrist were performed in 88 healthy children, 5-15 years of age. We assessed the number of bony depressions within the carpals/proximal metacarpals on both modalities, separately and combined. A total of 75 carpal depressions were identified on radiography compared to 715 on MRI. The number of bony depressions identified radiographically showed no statistically significant difference across age-groups. Within the metacarpals, there was no significant difference between bony depressions identified by MRI or radiography, except at the bases of the second metacarpal. Bony depressions that resemble erosions are normal findings in the wrist in children. MRI identifies more depressions than radiographs in the carpus. Some bony depressions occur at typical locations and should be accounted for when assessing the wrist in JIA to avoid overstaging. (orig.)

Avenarius, Derk M.F.; Eldevik, Petter [University Hospital North Norway, Department of Radiology, Tromsoe (Norway); Ording Mueller, Lil-Sofie [University Hospital North Norway, Department of Radiology, Tromsoe (Norway); Great Ormond Street Hospital for Children, Department of Radiology, London (United Kingdom); Owens, Catherine M. [Great Ormond Street Hospital for Children, Department of Radiology, London (United Kingdom); University College London, Institute of Child Health, London (United Kingdom); Rosendahl, Karen [Haukeland University Hospital, Department of Radiology, Bergen (Norway); University of Bergen, Department of Surgical Sciences, Bergen (Norway); Great Ormond Street Hospital for Children, Department of Radiology, London (United Kingdom)

2012-07-15

86

Computed tomography of the orbital lesions  

International Nuclear Information System (INIS)

The use of computed tomography in investigation of orbital lesions was of value for the localization of the lesions as well as making the specific diagnosis. We advocated the combined use of transverse axial section and contrast enhancement in CT as a routine procedure often including coronal section in the diagnosis of orbital lesions because of its usefulness and more precise three dimensional imaging. The authors examined 68 patients with various ophthalmic problems by EMI-CT scanner 5005 from October 1977 to November 1979. Fifty one orbital lesions out of 68 CT scans were analyzed by CT, angiography and operative findings and results were as follows; 1. Among 43 males and 25 females, their age range was from 4 months to 66 years with the most frequent age group of first decade (17 cases; 25%) 2. The distribution of the lesions was mucocele, pseudotumor, optic nerve atrophy, metastasis, lacrimal gland tumor, persistent hypertrophic primary vitreous, granulosa cell myoblastoma, hemangioma in order with 13 malignancies (25%). 3. It was difficult to differentiate pathological diagnosis of the lesions, but the character of the lesions was determined by its characteristic location, and its relationship to eyeball, optic nerve, extraocular muscles and bony orbit. 4. It was thought that more accurate diagnosis of orbital lesions could be made by development of CT scanner having fine matrix, short time exposure and thin slice in the future.

1980-06-01

87

Computed tomography of the orbital lesions  

Energy Technology Data Exchange (ETDEWEB)

The use of computed tomography in investigation of orbital lesions was of value for the localization of the lesions as well as making the specific diagnosis. We advocated the combined use of transverse axial section and contrast enhancement in CT as a routine procedure often including coronal section in the diagnosis of orbital lesions because of its usefulness and more precise three dimensional imaging. The authors examined 68 patients with various ophthalmic problems by EMI-CT scanner 5005 from October 1977 to November 1979. Fifty one orbital lesions out of 68 CT scans were analyzed by CT, angiography and operative findings and results were as follows; 1. Among 43 males and 25 females, their age range was from 4 months to 66 years with the most frequent age group of first decade (17 cases; 25%) 2. The distribution of the lesions was mucocele, pseudotumor, optic nerve atrophy, metastasis, lacrimal gland tumor, persistent hypertrophic primary vitreous, granulosa cell myoblastoma, hemangioma in order with 13 malignancies (25%). 3. It was difficult to differentiate pathological diagnosis of the lesions, but the character of the lesions was determined by its characteristic location, and its relationship to eyeball, optic nerve, extraocular muscles and bony orbit. 4. It was thought that more accurate diagnosis of orbital lesions could be made by development of CT scanner having fine matrix, short time exposure and thin slice in the future.

Hong, Seong Eon; Suh, Soo Jhi; Kim, Ho Kyun; Kim, Soon Yong [Kyung Hee University School of Medicine, Seoul (Korea, Republic of)

1980-06-15

88

MRI findings of cyclops lesions of the knee  

Scientific Electronic Library Online (English)

Full Text Available SciELO South Africa | Language: English Abstract in english Cyclops lesions develop in the anterior aspect of the intercondylar notch typically after anterior cruciate ligament (ACL) reconstruction or injury. It is a lesion consisting of fibrous tissue with or without cartilage and bony components. A cyclops lesion is one of the causes for reduced extension [...] and, in the cases reported here, also knee pain or discomfort after ACL reconstruction. We present the MRI features, particularly the features on proton density weighted turbo spin echo (PDW TSE) and proton density weighted turbo spin echo fat saturation (PDW TSE FS) sequences of four cases of cyclops lesions, and distinguish between the MRI findings of large and small lesions. We also describe a cyclops lesion after a posterior cruciate ligament reconstruction, not described in literature before.

Minné, C; Velleman, MD; Suleman, FE.

89

Incidence of dehiscence of the bony roof of the superior semicircular canal by CT imaging  

International Nuclear Information System (INIS)

Dehiscence of the bony roof of the superior semicircular canal (SSCC) is rare, but it has been recognized by otologists since Minor et al first described superior canal dehiscence syndrome (SCDS). In this study, dehiscence of the bony roof of SSCC was incidentally detected in three patients with benign paroxysmal positional vertigo out of 49 serial patients with vertigo and dizziness by multi-slice computed tomography. Although detection of dehiscence of the SSCC by ultra-high-resolution CT imaging of the temporal bones has been required for a diagnosis of SCDS, this study showed that dehiscence of the bony roof of the SSCC can be an incidental finding and therefore is not specific for SCDS. (author)

2003-12-01

90

[A case of multiple bony pain due to metastatic malignant pheochromocytoma successfully treated with strontium-89].  

Science.gov (United States)

A 50-year-old woman complaining of right flank pain visited our hospital. Computed tomography revealed adrenal gland tumor measuring 10 cm in diameter, and multiple bone and liver metastases. It was diagnosed as a malignant pheochromocytoma by means of endocrinological examination and metaiodobenzylguanidine scintigraphy. Although 8 courses of cyclophosphamide, vincristine and dacarbazine therapy were performed, the tumor grew larger gradually, and the bony pain progressed and became uncontrollable with oxycodone hydrochloride. After zoredronic acid and strontium-89 were administered, the bony pain reduced, and the opioid usage could be reduced. In accordance with disease progression, the bony pain progressed again, but the readministration of strontium-89 could diminish the pain again. To our knowledge, this is the first case of malignant pheochromocytoma which strontium-89 was administered, and was effective. PMID:24759495

Takeshima, Teppei; Namura, Kazuhiro; Sekiguchi, Zenkichi; Takizawa, Akitoshi; Tsuchiya, Futoshi; Iwasaki, Akira; Ogi, Shigeyuki

2014-03-01

91

Association between condylar morphology and changes in bony microstructure and subsynovial inflammation in experimental temporomandibular joint arthritis.  

DEFF Research Database (Denmark)

Association between condylar morphology and changes in bony microstructure and subsynovial inflammation in experimental temporomandibular joint arthritis. 86. Congress of the European Orthodontic Society, Slovenien, 2010.

Kristensen, Kasper Dahl; Hauge, Ellen Margrethe

92

POEMS (polyneuropathy, organomegaly, endocrinopathy, M protein, skin lesions) syndrome: a South America's report POEMS (polineuropatia, organomegalia, endocrinopatia, proteína M, alterações de pele): relato sul-americano  

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The POEMS syndrome, also known as Crow-Fukase syndrome, is an unusual systemic disorder described mainly in Asian individuals. It is characterized by the presence of (P)polyneuropathy, (O)organomegaly, (E)endocrinopathy, (M) M-protein, and (S) skin changes. Several other associated condictions such as sclerotic bone lesions, Castleman disease, low-grade fever, edema and hematologic disorders are usually seen. We describe five Brazilian patients with this syndrome. Two patients presented Castl...

Ana Claudia Celestino Leite; Nascimento, Osvaldo J. M.; Marco Antonio Lima; Maria José Andrada-Serpa

2007-01-01

93

Condylar bony changes in patients with temporomandibular disorders: a CBCT study  

Energy Technology Data Exchange (ETDEWEB)

Diagnosis of osteoarthritis most commonly depends on clinical and radiographic findings. The present study attempted to observe the bony changes in temporomandibular joint (TMJ) patients from all age groups. The first-visit clinical records and cone beam computed tomography (CBCT) data of 440 TMJs from 220 consecutive TMJ patients were reviewed retrospectively. The most frequent condylar bony change observed was sclerosis (133 joints, 30.2%) followed by surface erosion (129 joints, 29.3%), flattening of the articular surface (112 joints, 25.5%), and deviation in form (58 joints, 13.2%), which included 33 TMJs in a cane-shape, 16 with a lateral or medial pole depression, 6 with posterior condylar surface flattening, and 3 with a bifid-shaped condyle. Fifty-three joints (12.0%) showed hypoplastic condyles but only 1 joint showed hyperplasia. Osteophyte was found in 35 joints (8.0%) and subcortical cyst in 24 joints (5.5%), 5 of which had surface erosion as well. One hundred nineteen joints (27.0%) had only one kind of condylar bony change, 66 joints (15.0%) had two, 52 joints (11.8%) had three, 12 joints (5.0%) had four, and 6 joints (1.4%) had five kinds of condylar bony changes at the same time. Eighty-five (65.9%) of 129 joints with surface erosion had pain recorded at the chief complaint. With more widespread use of CBCT, more specific or detailed guidelines for osteoarthritis are needed.

Nah, Kyung Soo [Dept. of Oral and Maxillofacial Radiology, School of Dentistry, Pusan National University, Yangsan (Korea, Republic of)

2012-09-15

94

Another CT sign of sinonasal polyposis: truncation of the bony middle turbinate  

Energy Technology Data Exchange (ETDEWEB)

In order to study the features of sinonasal polyposis (SNP) on CT, 100 consecutive coronal sinus CT examinations done for chronic inflammatory sinonasal disease were reviewed. The CT findings of the 27 fully documented SNPs were analyzed. All our SNPs were bilateral. There was a strong tendency for extensive involvement. Nasal polyps were seen in 22 of 27(81 %); bony trabecular deossification in 23 of 27 (85 %); widening of infundibulum in 26 of 27(96 %). We discovered a new sign ``truncation of the bony middle turbinate``, where the bulbous part of bony middle turbinate was missing, in 15 of 26 (58 %) of SNP patients without a previous history of middle turbinectomy, 12 of 15(80 %) were bilateral. The one SNP patient (1 of 27) with previous middle turbinectomy was not regarded to be real truncation. Truncation of the bony middle turbinate is a characteristic and easily recognizable ancillary sign, and is not seen in other patterns of sinusitis. Together with other features on coronal sinus CT, this adds diagnostic confidence in diagnosing sinonasal polyposis. (orig.). With 4 figs., 2 tabs.

Liang, E.Y. [Department of Diagnostic Radiology and Organ Imaging, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin (Hong Kong); Lam, W.W.M. [Department of Diagnostic Radiology and Organ Imaging, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin (Hong Kong); Woo, J.K.S. [Division of Otorhinolaryngology, Department of Surgery, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin (Hong Kong); Hasselt, C.A. van [Division of Otorhinolaryngology, Department of Surgery, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin (Hong Kong); Metreweli, C. [Division of Otorhinolaryngology, Department of Surgery, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin (Hong Kong)

1996-08-01

95

Another CT sign of sinonasal polyposis: truncation of the bony middle turbinate  

International Nuclear Information System (INIS)

In order to study the features of sinonasal polyposis (SNP) on CT, 100 consecutive coronal sinus CT examinations done for chronic inflammatory sinonasal disease were reviewed. The CT findings of the 27 fully documented SNPs were analyzed. All our SNPs were bilateral. There was a strong tendency for extensive involvement. Nasal polyps were seen in 22 of 27(81 %); bony trabecular deossification in 23 of 27 (85 %); widening of infundibulum in 26 of 27(96 %). We discovered a new sign ''truncation of the bony middle turbinate'', where the bulbous part of bony middle turbinate was missing, in 15 of 26 (58 %) of SNP patients without a previous history of middle turbinectomy, 12 of 15(80 %) were bilateral. The one SNP patient (1 of 27) with previous middle turbinectomy was not regarded to be real truncation. Truncation of the bony middle turbinate is a characteristic and easily recognizable ancillary sign, and is not seen in other patterns of sinusitis. Together with other features on coronal sinus CT, this adds diagnostic confidence in diagnosing sinonasal polyposis. (orig.). With 4 figs., 2 tabs

1996-08-01

96

Effect of antiresorptive drugs on bony turnover in the jaw: denosumab compared with bisphosphonates.  

Science.gov (United States)

Osteonecrosis of the jaw as a result of treatment with receptor activators of nuclear factor kappa-B ligand (RANKL) inhibitors (denosumab) is a new type of bony necrosis, the exact pathogenesis of which is unknown. Our aim was to find out whether the turnover of bone in the jaw is increased after denosumab has been given compared with other skeletal sites, and if that turnover might have a role in denosumab-related osteonecrosis of the jaw (DRONJ). Bone scintigraphic images of 45 female patients with breast cancer and bone metastases were analysed retrospectively, and divided into 3 groups: those given denosumab, those given a bisphosphonate, and a control group (n=15 in each). All patients had bone scintigraphy before treatment (T0) and during the course of treatment after 12 (T1) and 24 (T2) months. The data were analysed quantitatively using 6 preset bony regions of interest. There was similar turnover of bone in the mandible compared with other skeletal sites (such as the femur), while the maxilla showed significantly higher turnover. None of the bony regions investigated showed any significant changes after the bisphosphonate had been given. There was a tendency to increase bone turnover in those patients taking denosumab. The bone turnover of the jawbone is not overtly changed either by a bisphosphonate or denosumab, so it seems unlikely that oversuppression of bony turnover in the jawbones plays an important part either in the pathogenesis of DRONJ or in the bisphosphonate-related osteonecrosis of the jaw (BRONJ). PMID:24582013

Ristow, Oliver; Gerngroß, Carlos; Schwaiger, Markus; Hohlweg-Majert, Bettina; Kehl, Victoria; Jansen, Heike; Hahnefeld, Lilian; Koerdt, Steffen; Otto, Sven; Pautke, Christoph

2014-04-01

97

First Record of Eocene Bony Fishes and Crocodyliforms from Canada's Western Arctic  

Science.gov (United States)

Background Discovery of Eocene non-marine vertebrates, including crocodylians, turtles, bony fishes, and mammals in Canada’s High Arctic was a critical paleontological contribution of the last century because it indicated that this region of the Arctic had been mild, temperate, and ice-free during the early – middle Eocene (?53–50 Ma), despite being well above the Arctic Circle. To date, these discoveries have been restricted to Canada’s easternmost Arctic – Ellesmere and Axel Heiberg Islands (Nunavut). Although temporally correlative strata crop out over 1,000 km west, on Canada’s westernmost Arctic Island – Banks Island, Northwest Territories – they have been interpreted as predominantly marine. We document the first Eocene bony fish and crocodyliform fossils from Banks Island. Principal Findings We describe fossils of bony fishes, including lepisosteid (Atractosteus), esocid (pike), and amiid, and a crocodyliform, from lower – middle Eocene strata of the Cyclic Member, Eureka Sound Formation within Aulavik National Park (?76°N. paleolat.). Palynology suggests the sediments are late early to middle Eocene in age, and likely spanned the Early Eocene Climatic Optimum (EECO). Conclusions/Significance These fossils extend the geographic range of Eocene Arctic lepisosteids, esocids, amiids, and crocodyliforms west by approximately 40° of longitude or ?1100 km. The low diversity bony fish fauna, at least at the family level, is essentially identical on Ellesmere and Banks Islands, suggesting a pan-High Arctic bony fish fauna of relatively basal groups around the margin of the Eocene Arctic Ocean. From a paleoclimatic perspective, presence of a crocodyliform, gar and amiid fishes on northern Banks provides further evidence that mild, year-round temperatures extended across the Canadian Arctic during early – middle Eocene time. Additionally, the Banks Island crocodyliform is consistent with the phylogenetic hypothesis of a Paleogene divergence time between the two extant alligatorid lineages Alligator mississippiensis and A. sinensis, and high-latitude dispersal across Beringia.

Eberle, Jaelyn J.; Gottfried, Michael D.; Hutchison, J. Howard; Brochu, Christopher A.

2014-01-01

98

Comparison of megavoltage position verification for prostate irradiation based on bony anatomy and implanted fiducials  

International Nuclear Information System (INIS)

Purpose: The patient position during radiotherapy treatment of prostate cancer can be verified with the help of portal images acquired during treatment. In this study we quantify the clinical consequences of the use of image-based verification based on the bony anatomy and the prostate target itself. Patients and methods: We analysed 2025 portal images and 23 computed tomography (CT) scans from 23 patients with prostate cancer. In all patients gold markers were implanted prior to CT scanning. Statistical data for both random and systematic errors were calculated for displacements of bones and markers and we investigated the effectiveness of an off-line correction protocol. Results: Standard deviations for systematic marker displacement are 2.4 mm in the lateral (LR) direction, 4.4 mm in the anterior-posterior (AP) direction and 3.7 mm in the caudal-cranial direction (CC). Application of off-line position verification based on the marker positions results in a shrinkage of the systematic error to well below 1 mm. Position verification based on the bony anatomy reduces the systematic target uncertainty to 50% in the AP direction and in the LR direction. No reduction was observed in the CC direction. For six out of 23 patients we found an increase of the systematic error after application of bony anatomy-based position verification. Conclusions: We show that even if correction based on the bony anatomy is applied, considerable margins have to be set to account for organ motion. Our study highlights that for individual patients the systematic error can increase after application of bony anatomy-based position verification, whereas the population standard deviation will decrease. Off-line target-based position verification effectively reduces the systematic error to well below 1 mm, thus enabling significant margin reduction

2003-07-01

99

Bone lesions  

International Nuclear Information System (INIS)

The purpose of this study is to evaluate the ability of opposed-phase T2*-weighted gradient-field-echo (T2*FE) MR imaging to image bone lesions. The series included 27 bone tumors and 12 benign compression fractures. Images were acquired on a 0.5 T magnet with T2*FE imaging (300/22[repetition time msec/echo time msec], 20deg). Results were compared with those of T1-weighted spin-echo (T1 SE) images (500/20-40) and T2-weighted spin-echo(T2 SE) images (2000/80). Shorter (about one-third or two-third) scanning time was required to obtain T2*FE images than to obtain T2 SE images. T2*FE images were superior to T2 SE images in describing bone tumors as high-intensity areas or in delineating the tumors and adjacent soft-tissue. In most cases, T2*FE images were equal to T1 SE images in depicting bone lesions. T2*FE images could demonstrate some lesions which were not clearly detected on T1 SE images. On T2*FE images, a contrast-noise ratio (C/N) was calculated for each lesion. The value of C/N was helpful to distinguish vertebral tumors from benign compression fractures. In conclusion, T2*FE images together with T1 SE images are advantageous to evaluate bone lesions. (author)

1990-01-01

100

Clival lesion incidentally discovered on cone-beam computed tomography: A case report and review of the literature  

Science.gov (United States)

An osteolytic lesion with a small central area of mineralization and sclerotic borders was discovered incidentally in the clivus on the cone-beam computed tomography (CBCT) of a 27-year-old male patient. This benign appearance indicated a primary differential diagnosis of non-aggressive lesions such as fibro-osseous lesions and arrested pneumatization. Further, on magnetic resonance imaging (MRI), the lesion showed a homogenously low T1 signal intensity with mild internal enhancement after post-gadolinium and a heterogeneous T2 signal intensity. These signal characteristics might be attributed to the fibrous tissues, chondroid matrix, calcific material, or cystic component of the lesion; thus, chondroblastoma and chondromyxoid fibroma were added to the differential diagnosis. Although this report was limited by the lack of final diagnosis and the patient lost to follow-up, the incidental skull base finding would be important for interpreting the entire volume of CBCT by a qualified oral and maxillofacial radiologist.

Tadinada, Aditya; Rengasamy, Kandasamy; Fellows, Douglas; Lurie, Alan G.

2014-01-01

 
 
 
 
101

Anatomic study of a particular type of vascular lesion associated with tibial fractures.  

Science.gov (United States)

Proximal tibiofibular dislocations are rare lesions, especially as they may pass unnoticed when associated with tibial fractures. Anatomically, there is bony and ligamentous predisposition to upward and backward dislocation of the proximal tibiofibular joint which is promoted by the shortening of the lower limb accompanying a tibial fracture. We report 3 tibial fractures associated with acute ischemia due to proximal tibiofibular dislocation, an association never previously described. This lesion and its mechanism were studied anatomically. PMID:2617412

Tricoire, J L; Lefèbvre, D

1989-01-01

102

An osseous lesion in a 10-year-old boy with Hodgkin's lymphoma: a case report  

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Abstract Introduction Osseous involvement of Hodgkin's lymphoma is uncommon. When osteolytic lesions are seen on imaging it is important to evaluate potential other causes. Case presentation We report the case of a 10-year-old Caucasian boy who presented to our facility with a bony lesion of the right clavicle and enlarged cervical lymph nodes. A simultaneous biopsy of the lymph node and of the osteolytic process of his right proximal clavicle was performed and ...

van den Akker Machiel; Zudekov Vadiem; Moser Asher; Kapelushnik Joseph

2011-01-01

103

The diagnostic value of needle biopsy for musculoskeletal lesions  

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The purpose of this study was to assess the diagnostic value of imaging-guided core needle biopsy for the diagnosis of musculoskeletal lesions. Between 2004 and 2007, 309 biopsies (ultrasound 151, computed tomography 89, and fluoroscopy 69) were included. There were 142 soft tissue and 167 bony lesions. Diagnostic yields and accuracies were assessed using the chi-square test or Fisher’s exact test with Bonferroni’s correction when necessary. Overall diagnostic yield was 90.6% for all 309 ...

Sung, Ki-sun; Seo, Sung-wook; Shon, Min-soo

2009-01-01

104

Femoral arterial puncture: comparison of using the inguinal crease and bony landmarks  

Energy Technology Data Exchange (ETDEWEB)

We tried to compare the accuracy of using bony landmarks and inguinal crease landmarks for performing femoral artery puncture and to determine an ideal puncture site. We studied ninety consecutive patients who underwent femoral arterial puncture for performing angiogram. For the evaluation of bony landmarks, the pelvis and inguinal areas were divided into 8 zones according to 7 lines that were drawn parallel to the line drawn between the anterior superior iliac spine and the pubic tubercle. For evaluation of the inguinal crease as a landmark, the 8 zones above and 4 zones below the inguinal crease were determined. The zones were divided by 11 lines drawn parallel to the inguinal crease, and the interval between each line was 1 cm. Locations of the inguinal ligament and femoral bifurcation were recorded for every patient according to the above zones, and an ideal zone for the femoral arterial puncture was decided upon. The ideal zone was considered if the locations of all of inguinal ligaments were above the zone and the least possibility to puncture was below the femoral bifurcation. On the bony landmark, the femoral bifurcations were located at zone 3 in 1 patient (1.1%), at zone 4 in 2 patients (2.2%), at zone 5 in 3 patients (3.3%), at zone 6 in 24 patients (26.7%), and at zone 7 in 44 patients (48.9%). Inguinal ligaments were at zone 1 in 2 patient (3.0%), at zone 2 in 34 patients (50.7%), at zone 3 in 25 patients (37.3%), and at zone 4 in 6 patients (8.9%). When the inguinal creases were used as a landmark, the femoral bifurcations were located at zone 4 in 4 patients (4.4%), at zone 3 in 19 patients (21.1%). at zone 2 in 30 patients (33.3%), at zone 1 in 19 patients (21.1%), at zone -1 in 13 patients (14.4%), at zone -2 in 3 patients (3.3%) and at zone -4 in 2 patients (2.2%). Inguinal ligaments were at zone 8 in 7 patients (10.4%), at zone 7 in 11 patients (16.4%), at zone 6 in 19 patients (28.4%), at zone 5 in 20 patients (29.9%), at zone 4 in 7 patients (10.4%), and at zone 3 in 3 patients (4.5%). Therefore, the best zone for femoral arterial puncture was zone 5 with using bony landmarks and zone 2 with using inguinal crease landmarks. In terms of zone 5 on the bony landmark, every locations of inguinal ligaments was above it and 84 patients (93.4%) had their femoral bifurcation below it, excluding the 6 patients who had their femoral bifurcations at zones 3, 4, and 5. Therefore, zone 5 with using the bony landmarks was a good indicator for femoral arterial puncture. In case of zone 2 on the inguinal crease landmark, although every location of the inguinal ligament was above it, 53 patients (58.8%) had their femoral bifurcation above it at zone 4, 3, and 2. So, it was not a good indicator for femoral arterial puncture. Bony landmarks are more accurate indicators for performing femoral arterial puncture than the inguinal crease landmark. Zone 5 on the bony landmark is an ideal location for femoral arterial puncture.

Chung, Hwan Hoon; Ha, Jong Soo; Cha, Sang Hoon; Kim, Baek Hyun; Lee, Kee Yeol; Kim, Taik Kun; Lee, Seung Hwa; Kim, Jung Hyuck; Seol, Hae Seol [Korea University College of Medicine, Seoul (Korea, Republic of)

2006-04-15

105

Medial depression with bony dehiscence of lamina papyracea as an anatomic variation: CT evaluation  

International Nuclear Information System (INIS)

To evaluate the incidence and CT findings of the medial depression and bony dehiscence of lamina papyracea as an anatomic variation. 1472 PNS CTs of the patients with symptoms of chronic sinusitis were retrospectively evaluated. The total incidence of depressed lamina papyracea as an anatomic variation was 3.5%(52/1472) on PNS CT. There was a statistically significant correlation between the increasing age and the incidence of depressed lamina papyracea. Depression of lamina papyracea anterior to the basal lamella were more common than those of the posterior depression. Associated findings were herniation of adjacent fatty tissue in all cases and the medial bowing and hypertrophied configuration of the medial rectus muscle without significant herniation in 19 cases(34%). Nontraumatic, asymptomatic depression with bony dehiscence of lamina papyracea as an anatomic variation is not uncommon with the incidence of 3.5%. Recognition of its existence and degree may be helpful in avoiding various ocular complication during ethmoid surgery

1994-09-01

106

Prostate position relative to pelvic bony anatomy based on intraprostatic gold markers and electronic portal imaging  

International Nuclear Information System (INIS)

Purpose: To describe the relative positions and motions of the prostate, pelvic bony anatomy, and intraprostatic gold fiducial markers during daily electronic portal localization of the prostate. Methods and Materials: Twenty prostate cancer patients were treated supine with definitive external radiotherapy according to an on-line target localization protocol using three or four intraprostatic gold fiducial markers and an electronic portal imaging device. Daily pretherapy and through-treatment electronic portal images (EPIs) were obtained for each of four treatment fields. The patients' pelvic bony anatomy, intraprostatic gold markers, and a best visual match to the target (i.e., prostate) were identified on simulation digitally reconstructed radiographs and during daily treatment setup and delivery. These data provided quantitative inter- and intrafractional analysis of prostate motion, its position relative to the bony anatomy, and the individual intraprostatic fiducial markers. Treatment planning margins, with and without on-line localization, were subsequently compared. Results: A total of 22,266 data points were obtained from daily pretherapy and through-treatment EPIs. The pretherapy three-dimensional (3D) average displacement of the fiducial markers, as a surrogate for the prostate, was 5.6 mm, which improved to 2.8 mm after use of the localization protocol. The bony anatomy 3D average displacement was 4.4 mm both before and after localization to the prostate (p = 0.46). Along the superior-inferior (SI), anterior-posterior (AP), and right-left (RL) axes, the average prostate displacement improved from 2.5, 3.7, and 1.9 mm, respectively, before localization to 1.4, 1.6, and 1.1 mm after (all p < 0.001). The pretherapy to through-treatment position of the bony landmarks worsened from 1.7 to 2.5 mm (p < 0.001) in the SI axis, remained statistically unchanged at 2.8 mm (p = 0.39) in the AP axis, and improved from 2.0 to 1.2 mm in the RL axis (p < 0.001). There was no significant intrafractional displacement of prostate position or bony anatomic landmarks. An intermarker distance was identified for all fiducial markers, and 96 were followed daily. Seventy-nine percent had a standard deviation of <1 mm, and 96% were <1.5 mm. Margins were 5.1, 7.3, and 5.0 mm in the SI, AP, and RL axes, respectively, before localization and 2.7, 2.9, and 2.8 mm after localization. Conclusions: Significant interfractional motion exists for patients' prostate and pelvic bony anatomy. However, these move independently, so the pelvic bony anatomy should not be used as a surrogate for prostate motion. Fiducial markers are stable within the prostate and allow significant margin reduction when used for on-line localization of the prostate

2005-11-01

107

Correction of bony deformities around knee by hemicallotasis using an innovative apparatus  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Background: Valgus and varus deformities around the knee are common. Various osteotomies and apparatuses have been described to correct these deformities. Methods: Bony deformities around knee joint in thirty patients (36 joints) were corrected by osteotomy in upper tibia or lower femur which was stabilized and distracted with innovatively designed and locally fabricated T-shaped external fixator-cum-distractor. The age of the patients ranged from 5 to 48 years. The causes of...

Kundu Z; Sangwan S; Siwach R; Guliani Gulshan

2005-01-01

108

Condylar bony changes in patients with temporomandibular disorders: a CBCT study  

Science.gov (United States)

Purpose Diagnosis of osteoarthritis most commonly depends on clinical and radiographic findings. The present study attempted to observe the bony changes in temporomandibular joint (TMJ) patients from all age groups. Materials and Methods The first-visit clinical records and cone beam computed tomography (CBCT) data of 440 TMJs from 220 consecutive TMJ patients were reviewed retrospectively. Results The most frequent condylar bony change observed was sclerosis (133 joints, 30.2%) followed by surface erosion (129 joints, 29.3%), flattening of the articular surface (112 joints, 25.5%), and deviation in form (58 joints, 13.2%), which included 33 TMJs in a cane-shape, 16 with a lateral or medial pole depression, 6 with posterior condylar surface flattening, and 3 with a bifid-shaped condyle. Fifty-three joints (12.0%) showed hypoplastic condyles but only 1 joint showed hyperplasia. Osteophyte was found in 35 joints (8.0%) and subcortical cyst in 24 joints (5.5%), 5 of which had surface erosion as well. One hundred nineteen joints (27.0%) had only one kind of condylar bony change, 66 joints (15.0%) had two, 52 joints (11.8%) had three, 12 joints (5.0%) had four, and 6 joints (1.4%) had five kinds of condylar bony changes at the same time. Eighty-five (65.9%) of 129 joints with surface erosion had pain recorded at the chief complaint. Conclusion With more widespread use of CBCT, more specific or detailed guidelines for osteoarthritis are needed.

2012-01-01

109

Knee joint secondary motion accuracy improved by quaternion-based optimizer with bony landmark constraints.  

Science.gov (United States)

Skin marker-based motion analysis has been widely used in biomechanical studies and clinical applications. Unfortunately, the accuracy of knee joint secondary motions is largely limited by the nonrigidity nature of human body segments. Numerous studies have investigated the characteristics of soft tissue movement. Utilizing these characteristics, we may improve the accuracy of knee joint motion measurement. An optimizer was developed by incorporating the soft tissue movement patterns at special bony landmarks into constraint functions. Bony landmark constraints were assigned to the skin markers at femur epicondyles, tibial plateau edges, and tibial tuberosity in a motion analysis algorithm by limiting their allowed position space relative to the underlying bone. The rotation matrix was represented by quaternion, and the constrained optimization problem was solved by Fletcher's version of the Levenberg-Marquardt optimization technique. The algorithm was validated by using motion data from both skin-based markers and bone-mounted markers attached to fresh cadavers. By comparing the results with the ground truth bone motion generated from the bone-mounted markers, the new algorithm had a significantly higher accuracy (root-mean-square (RMS) error: 0.7 ± 0.1 deg in axial rotation and 0.4 ± 0.1 deg in varus-valgus) in estimating the knee joint secondary rotations than algorithms without bony landmark constraints (RMS error: 1.7 ± 0.4 deg in axial rotation and 0.7 ± 0.1 deg in varus-valgus). Also, it predicts a more accurate medial-lateral translation (RMS error: 0.4 ± 0.1 mm) than the conventional techniques (RMS error: 1.2 ± 0.2 mm). The new algorithm, using bony landmark constrains, estimates more accurate secondary rotations and medial-lateral translation of the underlying bone. PMID:21142329

Wang, Hongsheng; Zheng, Naiqaun Nigel

2010-12-01

110

Study of bony trabecular characteristics using bone morphometry and micro-CT  

International Nuclear Information System (INIS)

The research was done to investigate the effectiveness of 2D bony morphometry and microstructure of micro-computed tomography (micro-CT) on the osteoporotic bony change. We performed the bone morphometric analysis of proximal femur in ovariectomized rabbits with BMD and micro-CT examination. Twenty-one female (Newzeland, about 16 weeks old, 2.9-3.4 kg) rabbits were used. Three rabbits were sacrificed on the day when experiment began (Basline). The remaining 18 rabbits were divided into two groups. One group was ovariectomized bilaterally (OVX) and the other animals were subjected to sham operation (Sham). Bone specimens were obtained from the right and left femur of sacrificed rabbits. At intervals of 1,2,3,5,6 months respectively, BMD tests were performed on the proximal on the proximal femur by using PIXImus 2 (GE Lunar Co. USA), 2-dimensional bone morphometric analysis by custom computer program and 2D / 3D bone structure analysis by micro-CT (Skyscan1072, Antwerpen, Belgium). Statistical analysis was carried out for the correlation between bone morphometry, micro-CT and BMD. BV/TV, Tb.Th, Tb.N of micro-CT parameters showed higher values in sham group than OVX group. N.Nd/Ar.RI, N.NdNd, N.NdTm, N. TmTm, PmB/Ar.RI, 3-D BoxSlope of 2D morphometric parameters showed higher values in Sham group than OVX group. The micro-CT parameters of Tb.Sp. Tb.N were statistically significant correlated with BMD respectively. Several 2D morphometric parameters were statistically significant correlated with BMD respectively. Several parameters of 2D bony morphometry and micro-CT showed effective aspects on the osteoporotic bony change

2007-03-01

111

Split cord malformation with dorsally located bony spur: Report of four cases and review of literature  

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Split cord malformations (SCM) with a dorsally located bony spur are a very rare entity. The authors report a series of four such cases. The literature is reviewed regarding the pathogenesis and management of this uncommon variant of SCM. The presenting features include – scoliosis with motor and autonomic dysfunction (n = 1), scoliosis with cutaneous patch (n = 1), hypertrichotic area (n = 1), and motor deficits alone (n = 1). The location of spur was thoracic and lumbar in two patients (5...

Prasad, G. L.; Borkar, Sachin A.; Satyarthee, G. D.; Mahapatra, A. K.

2012-01-01

112

Management of Extensive Maxillofacial Trauma With Bony Foreign Body Within the Orbit From a Chainsaw Injury  

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Objective: The goal of this case report is to characterize injury patterns typical for chainsaw injuries to the face. We describe our approach to the soft tissue and skeletal injury patterns seen in these injuries. Methods: We present a case report of a traumatic chainsaw injury to the face. Results: A literature review of the typical injury patterns seen in chainsaw injuries to the face is discussed. Fractures to the bony orbit are on of the most common findings. Traumatic orbital fractures ...

Craft, Randall O.; Eberlin, Kyle R.; Stella, Michael H.; Caterson, Edward J.

2011-01-01

113

Currarino triad: Complex of anorectal malformation, sacral bony abnormality, and presacral mass  

Energy Technology Data Exchange (ETDEWEB)

The Currarino triad is a unique complex of congenital caudal anomalies including anorectal malformation, sacral bony abnormality, and presacral mass. The usual symptomatology is constipation due to anorectal stenosis. Contrast enema and computed tomographic myelography are the imaging modalities of choice for diagnostic confirmation and clarification of the anomalies. The clinical features, unique radiologic appearance, and importance of correct diagnosis of the Currarino triad are reviewed.

Kirks, D.R.; Merten, D.F.; Filston, H.C.; Oakes, W.J.

1984-04-01

114

Valor predicts the thyroid hormones in the evolution the transplant bony marrow  

International Nuclear Information System (INIS)

In this work you values the valor I predict the thyroid hormones in the bony marrow transplant evolution as factors the metabolisms oxidative and the synthesis albumins. The patients received conditioning treatments to the transplant and in the postoperational. The received radiations were 1000 cGy lateral cube, with blocking lung, to those that were subjected 3 sessions irradiation, they are practiced a transplant marrow allogeneic

1998-10-19

115

Parasellar lesions  

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The sellar and parasellar region is an anatomically complex area that represents a crucial crossroad of important adjacent structures, e.g. orbits, cavernous sinus and its content, polygon of Willis, hypothalamus through the pituitary stalk and dural reflections forming the diaphragm sellae and the walls of the cavernous sinuses. Although the cavernous sinus represents the most relevant parasellar structure, from the practical and clinical point of view all the structures that surround the sella turcica can be included in the parasellar region. CT and, mainly, MRI are the imaging modalities to study and characterise the normal anatomy and the majority of processes in this region. We present a practical short review of the most relevant CT and MRI characteristics, such as location, nature of contrast enhancement and presence of cystic components, together with clinical findings, which permit differentiation of the most frequent and less common lesions found in the parasellar region. Learning objectives: A short review of the anatomy and clinical symptoms related to the parasellar region. Radiological characterisation, mainly by MRI, of the many lesions that alter the structure and function of sellar and parasellar anatomy. Description of the MRI features that permit differentiation among less common lesions. (orig.)

2005-03-01

116

Linhas escleróticas metafisárias em crianças e adolescentes em uso de alendronato Sclerotic metaphyseal lines in children and adolescents treated with alendronate  

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Full Text Available INTRODUÇÃO: Os bisfosfonatos inibem a reabsorção óssea pela interferência na ação dos osteoclastos. Dentre os efeitos adversos, as linhas escleróticas em metáfise de ossos longos são descritas como principal alteração radiográfica na faixa etária pediátrica. OBJETIVO: Avaliar a frequência de alterações radiográficas causadas pelo alendronato utilizado em crianças e adolescentes com baixa densidade óssea ou calcinose. PACIENTES E MÉTODOS: Foi realizado um estudo do tipo coorte retrospectiva analisando-se prontuários de 21 pacientes que fizeram uso de alendronato semanal por no mínimo 10 meses. Os pacientes realizaram radiografias de ossos longos antes do início do alendronato e aproximadamente um ano após o seu uso. RESULTADOS: Onze pacientes (52,3% apresentaram linhas escleróticas em metáfise dos ossos longos. A localização mais frequente foi em tíbia (8/11 pacientes, seguida de fêmur (7/11, úmero (6/11, rádio (4/11, ulna (3/11 e fíbula (2/11. Nenhum paciente apresentou regress??o das alterações radiográficas durante o tempo de evolução (até 1,1 ano após a suspensão do alendronato. CONCLUSÃO: Se usado com critério, o alendronato é seguro e as alterações radiográficas não mostraram ter um significado mais importante.INTRODUCTION: Bisphosphonates inhibit bone resorption by interfering with the action of osteoclasts. Among the adverse effects, sclerotic lines observed in the metaphysis of long bones have been described as the main imaging finding in pediatric patients. OBJECTIVE: To evaluate the frequency of radiographic changes caused by alendronate in children and adolescents with low bone density or calcinosis. PATIENTS AND METHODS: We conducted a cross-sectional study with 21 patients who were treated with once-weekly alendronate for at least 10 months. Patients underwent x-rays of long bones before the start of alendronate and approximately one year after its use. RESULTS: Eleven patients (52.3% had sclerotic lines in the metaphysis of long bones. The most frequent site was the tibia (8/11 patients, followed by the femur (7/11, humerus (6/11, radius (4/11, ulna (3/11, and fibula (2/11. Regression of radiographic changes during the study period (up to 1.1 years after discontinuation of alendronate was not observed. CONCLUSION: If used carefully, alendronate is safe and radiographic changes have not been shown to be clinically relevant.

Érika C.C. Silva

2010-06-01

117

Osteochondral lesions  

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MRI has demonstrated high diagnostic value in the assessment of musculoskeletal disease. Pathological joint changes, especially in the osteochondral region, are an important orthopedic problem because the signs and symptoms are vague and unspecific. Therefore, in early disease their extent and severity are difficult to ascertain clinically. Early diagnosis and exact staging are recommended for sufficient therapeutic management. MR imaging has proved to be the method of choice in the valuation of osteochondral lesions and helps to prevent late-stage disease and joint damage. (orig.)

1995-02-01

118

Endoscopic Orientation of the Parasellar Region in Sphenoid Sinus with Ill-Defined Bony Landmarks: An Anatomic Study  

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The sphenoid bony landmarks are important for endoscopic orientation in skull base surgery but show a wide range of variations. We aimed to describe an instructional model for the endoscopic parasellar anatomy in sphenoid sinuses with ill-defined bony landmarks. Five preserved injected cadaveric heads and four sides of dry skulls were studied endoscopically via transethmoid, transsphenoidal approach. The parasellar region was exposed by drilling along the maxillary nerve (V2) canal [the lengt...

2010-01-01

119

Computed tomographic features of the bony canal of the cochlear nerve in pediatric patients with unilateral sensorineural hearing loss  

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The aim of this study was to evaluate the diameters of the various bony canals of the inner ear in patients with sensorineural hearing loss (SNHL) and establish criteria for detecting hypoplasia of the bony canal of the cochlear nerve. Measurements obtained in 118 patients without inner ear malformations among 160 patients with unilateral SNHL were analyzed. The diameters of the internal auditory canal and the bony canals of the cochlear, vestibular, and facial nerves were measured on transverse or coronal computed tomographic images. Mean values (±standard deviation (SD)) were compared between the affected and unaffected ears, and statistical analysis was done. The diameter of the bony canal of the cochlear nerve was significantly smaller in affected ears than in unaffected ears (P<0.01). The affected ears could be divided into groups with (72 ears) and without (46 ears) bony canal stenosis. Most (60%) of the patients with unilateral SNHL showed a significant difference in the diameters of the bony canals of the cochlear nerve between the affected and unaffected sides; moreover, the mean value was significantly smaller in affected ears. The diameter of <1.7 mm on transverse images or <1.8 mm on coronal images suggests hypoplasia. (author)

2008-04-01

120

Directed Bmp4 expression in neural crest cells generates a genetic model for the rare human bony syngnathia birth defect.  

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Congenital bony syngnathia, a rare but severe human birth defect, is characterized by bony fusion of the mandible to the maxilla. However, the genetic mechanisms underlying this birth defect are poorly understood, largely due to limitation of available animal models. Here we present evidence that transgenic expression of Bmp4 in neural crest cells causes a series of craniofacial malformations in mice, including a bony fusion between the maxilla and hypoplastic mandible, resembling the bony syngnathia syndrome in humans. In addition, the anterior portion of the palatal shelves emerged from the mandibular arch instead of the maxilla in the mutants. Gene expression assays showed an altered expression of several facial patterning genes, including Hand2, Dlx2, Msx1, Barx1, Foxc2 and Fgf8, in the maxillary and mandibular processes of the mutants, indicating mis-patterned cranial neural crest (CNC) derived cells in the facial region. However, despite of formation of cleft palate and ectopic cartilage, forced expression of a constitutively active form of BMP receptor-Ia (caBmprIa) in CNC lineage did not produce the syngnathia phenotype, suggesting a non-cell autonomous effect of the augmented BMP4 signaling. Our studies demonstrate that aberrant BMP4-mediated signaling in CNC cells leads to mis-patterned facial skeleton and congenital bony syngnathia, and suggest an implication of mutations in BMP signaling pathway in human bony syngnathia. PMID:24785830

He, Fenglei; Hu, Xuefeng; Xiong, Wei; Li, Lu; Lin, Lisong; Shen, Bin; Yang, Ling; Gu, Shuping; Zhang, Yanding; Chen, YiPing

2014-07-15

 
 
 
 
121

The detection of sclerotic changes of the coronaries and heart valves by scanning beams (ultrafast computed tomography using EVOLUTION). Diagnostik von Coronar- und Herzklappenverkalkungen mit dem Elektronenstrahl-CT (Ultrafast-CT, Evolution)  

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With the advent of ultrafast computed tomography the range of diagnostic procedures for the quantitative determination of pathological changes in the coronary arteries has been broadened. The calcified coronary plaques found in this study, which in some of the patients were markedly pronounced, gave no immediate clue as to what extent sclerotic changes had already occurred in the coronaries examined. Nor was it possible on the basis of this method to pinpoint the vascular sections showing calcified plaques in patients undergoing maintenance dialysis. It may, however, permit careful predictions to be made for patients at a high risk of developing coronary artery disease. Sclerotic changes of the heart values occur with above-average frequency in dialysis patients and may be assessed quantitatively by the method described. The results described show that findings revealed by scanning electron beams may provide indirect information on metabolic processes in patients suffering from chronic ailments. (orig./MG)

Oldendorf, M. (Abt. fuer Roentgendiagnostik, Klinikum Nord der Stadt Nuernberg (Germany)); Zeitler, E. (Abt. fuer Roentgendiagnostik, Klinikum Nord der Stadt Nuernberg (Germany)); Braun, J. (Abt. fuer Roentgendiagnostik, Klinikum Nord der Stadt Nuernberg (Germany)); Weber, P. (Abt. fuer Roentgendiagnostik, Klinikum Nord der Stadt Nuernberg (Germany))

1994-02-01

122

Comparative study of notoungulate (Placentalia, Mammalia) bony labyrinths and new phylogenetically informative inner ear characters.  

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The phylogenetic relationships of notoungulates, an extinct group of predominantly South American herbivores, remain poorly resolved with respect to both other placental mammals and among one another. Most previous phylogenetic analyses of notoungulates have not included characters of the internal cranium, not least because few such features, including the bony labyrinth, have been described for members of the group. Here we describe the inner ears of the notoungulates Altitypotherium chucalensis (Mesotheriidae), Pachyrukhos moyani (Hegetotheriidae) and Cochilius sp. (Interatheriidae) based on reconstructions of bony labyrinths obtained from computed tomography imagery. Comparisons of the bony labyrinths of these taxa with the basally diverging notoungulate Notostylops murinus (Notostylopidae), an isolated petrosal from Itaboraí, Brazil, referred to Notoungulata, and six therian outgroups, yielded an inner ear character matrix of 25 potentially phylogenetically informative characters, 14 of them novel to this study. Two equivocally optimized character states potentially support a pairing of Mesotheriidae and Hegetotheriidae, whereas four others may be diagnostic of Notoungulata. Three additional characters are potentially informative for diagnosing more inclusive clades: one for crown Placentalia; another for a clade containing Kulbeckia, Zalambdalestes, and Placentalia; and a third for Eutheria (crown Placentalia plus stem taxa). Several other characters are apomorphic for at least one notoungulate in our study and are of potential interest for broader taxonomic sampling within Notoungulata to clarify currently enigmatic interrelationships. Measures of the semicircular canals were used to infer agility (e.g. capable of quick movements vs. lethargic movements) of these taxa. Agility scores calculated from these data generally corroborate interpretations based on postcranial remains of these or closely related species. We provide estimates of the low-frequency hearing limits in notoungulates based on the ratio of radii of the apical and basal turns of the cochlea. These limits range from 15?Hz in Notostylops to 149?Hz in Pachyrukhos, values comparable to the Asian elephant (Elephas maximus) and the California sea lion (Zalophus californianus) when hearing in air, respectively. PMID:24102069

Macrini, Thomas E; Flynn, John J; Ni, Xijun; Croft, Darin A; Wyss, André R

2013-11-01

123

Bony fish bycatch in the southern Brazil pink shrimp (Farfantepenaeus brasiliensis and F. paulensis fishery  

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Full Text Available Trawling for pink shrimp (Farfantepenaeus brasiliensis and F. paulensis catches also large quantities of fish, mostly bony fish, which are discarded, as they have no commercial value. Their composition and abundance were studied in an area that corresponded to the southeastern coastline of Brazil. Ninety one species were registered. Incidental fishing affected mainly small individuals and occured throughout the year. The year round rate of bony fish to shrimp catches was 10,5:1,0. Three assemblages of bony fishes could be identified, influenced by the seasonal variation of the water masses, the predominant group being associated with the Coastal Water, another with the penetration of colder waters onto the platform (SACW and a third group of a more homogenous distribution. The most critical period identified for the bycatch capture was the beginning of the winter, which was due to the overlapping of fish assemblages and the peak of fishing recruitment.A pesca de arrasto direcionada ao camarão-rosa, captura grande quantidade de peixes, em sua maioria teleósteos, que são rejeitados por não possuírem valor comercial. A composição e abundância destes foram estudadas em uma área no litoral sudeste do Brasil. Registramos 91 espécies e observou-se que a pesca incidental age principalmente sobre indivíduos jovens e ocorre durante o ano todo, produzindo um relação entre teleóteos e camarão de 10,5:1,0. Foram identificadas três ictiocenoses influenciadas pela sazonalidade das massas d'água, ocorrendo uma predominante associada a Água Costeira, outra associada a penetração da ACAS na plataforma e uma terceira com distribuição mais homogênea. O período mais crítico, para a captura da ictiofauna acompanhante, é o inicio do inverno devido a sobreposição de ictiocenoses e pico de recrutamento pesqueiro.

Marcelo Vianna

2005-07-01

124

The tree of life and a new classification of bony fishes.  

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The tree of life of fishes is in a state of flux because we still lack a comprehensive phylogeny that includes all major groups. The situation is most critical for a large clade of spiny-finned fishes, traditionally referred to as percomorphs, whose uncertain relationships have plagued ichthyologists for over a century. Most of what we know about the higher-level relationships among fish lineages has been based on morphology, but rapid influx of molecular studies is changing many established systematic concepts. We report a comprehensive molecular phylogeny for bony fishes that includes representatives of all major lineages. DNA sequence data for 21 molecular markers (one mitochondrial and 20 nuclear genes) were collected for 1410 bony fish taxa, plus four tetrapod species and two chondrichthyan outgroups (total 1416 terminals). Bony fish diversity is represented by 1093 genera, 369 families, and all traditionally recognized orders. The maximum likelihood tree provides unprecedented resolution and high bootstrap support for most backbone nodes, defining for the first time a global phylogeny of fishes. The general structure of the tree is in agreement with expectations from previous morphological and molecular studies, but significant new clades arise. Most interestingly, the high degree of uncertainty among percomorphs is now resolved into nine well-supported supraordinal groups. The order Perciformes, considered by many a polyphyletic taxonomic waste basket, is defined for the first time as a monophyletic group in the global phylogeny. A new classification that reflects our phylogenetic hypothesis is proposed to facilitate communication about the newly found structure of the tree of life of fishes. Finally, the molecular phylogeny is calibrated using 60 fossil constraints to produce a comprehensive time tree. The new time-calibrated phylogeny will provide the basis for and stimulate new comparative studies to better understand the evolution of the amazing diversity of fishes. PMID:23653398

Betancur-R, Ricardo; Broughton, Richard E; Wiley, Edward O; Carpenter, Kent; López, J Andrés; Li, Chenhong; Holcroft, Nancy I; Arcila, Dahiana; Sanciangco, Millicent; Cureton Ii, James C; Zhang, Feifei; Buser, Thaddaeus; Campbell, Matthew A; Ballesteros, Jesus A; Roa-Varon, Adela; Willis, Stuart; Borden, W Calvin; Rowley, Thaine; Reneau, Paulette C; Hough, Daniel J; Lu, Guoqing; Grande, Terry; Arratia, Gloria; Ortí, Guillermo

2013-01-01

125

Anatomical study of suboccipital vertebral arteries and surrounding bony structures using virtual reality technology  

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Background This work aimed to evaluate the efficacy of virtual reality (VR) technology in neurosurgical anatomy through a comparison of the virtual 3D microanatomy of the suboccipital vertebral arteries and their bony structures as part of the resection of tumors in the craniovertebral junction (CVJ) of 20 patients compared to the actual microanatomy of the vertebral arteries of 15 cadaveric headsets. Material/Methods The study was conducted with 2 groups of data: a VR group composed of 20 clinical cases and a physical body group (PB group) composed of 15 cadaveric headsets. In the VR group, the dissection and measurements of the vertebral arteries were simulated on a Dextroscope. In the PB group, the vertebral arteries in the cadaver heads were examined under a microscope and anatomical measurements of VA and bony structures were performed. The length and course of the vertebral arteries and its surrounding bony structures in each group were compared. Results The distances from the inferior part of the transverse process foramen (TPF) of C1 to the inferior part of TPF of C2 were 17.68±2.86 mm and 18.4±1.82 mm in the PB and VR groups, respectively. The distances between the middle point of the posterior arch of the atlas and the medial intersection of VA on the groove were 17.35±2.23 mm in the PB group and 18.13±2.58 mm in the VR group. The distances between the middle line and the entrance of VA to the lower rim of TPF of Atlas were 28.64±2.67 mm in PB group and 29.23±2.89 mm in VR group. The diameters of the vertebral artery (VA) at the end of the groove and foramen of C2 transverse process were 4.02±046 mm and 4.25±0.51 mm, respectively, in the PB group and 3.54±0.44 mm and 4.47±0.62 mm, respectively, in VR group. The distances between the VA lumen center and midline of the foramen magnum at the level of dural penetration was 10.4±1.13 mm in the PB group and 11.5±1.34 mm in the VR group (P>0.05). Conclusions VR technology can accurately simulate the anatomical features of the suboccipital vertebral arteries and their bony structures, which facilitates the planning of individual surgeries in the CVJ.

Ha, Wenbo; Yang, DeLin; Gu, Shixin; Xu, Qi-Wu; Che, Xiaoming; Wu, Jin-Song; Li, Wensheng

2014-01-01

126

A Bony Landmark ‘RAI Triangle’ to Prevent ‘Misplaced and Misdirected’ Medial Cut in SSRO  

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‘Rai triangle’, a new anatomic landmark on the medial surface of the ramus of the mandible which when identified and taken into consideration, may have a definite advantage. This is especially in terms of performing the medial horizontal cut which is an important and integral part of the sagittal split ramus osteotomy so as to avoid a bad split. The objective of this article is to propose an easily identifiable bony land mark, which is closely related to lingula of mandible that may ease ...

2011-01-01

127

Anatomical study of suboccipital vertebral arteries and surrounding bony structures using virtual reality technology.  

Science.gov (United States)

Background This work aimed to evaluate the efficacy of virtual reality (VR) technology in neurosurgical anatomy through a comparison of the virtual 3D microanatomy of the suboccipital vertebral arteries and their bony structures as part of the resection of tumors in the craniovertebral junction (CVJ) of 20 patients compared to the actual microanatomy of the vertebral arteries of 15 cadaveric headsets. Material and Methods The study was conducted with 2 groups of data: a VR group composed of 20 clinical cases and a physical body group (PB group) composed of 15 cadaveric headsets. In the VR group, the dissection and measurements of the vertebral arteries were simulated on a Dextroscope. In the PB group, the vertebral arteries in the cadaver heads were examined under a microscope and anatomical measurements of VA and bony structures were performed. The length and course of the vertebral arteries and its surrounding bony structures in each group were compared. Results The distances from the inferior part of the transverse process foramen (TPF) of C1 to the inferior part of TPF of C2 were 17.68±2.86 mm and 18.4±1.82 mm in the PB and VR groups, respectively. The distances between the middle point of the posterior arch of the atlas and the medial intersection of VA on the groove were 17.35±2.23 mm in the PB group and 18.13±2.58 mm in the VR group. The distances between the middle line and the entrance of VA to the lower rim of TPF of Atlas were 28.64±2.67 mm in PB group and 29.23±2.89 mm in VR group. The diameters of the vertebral artery (VA) at the end of the groove and foramen of C2 transverse process were 4.02±046 mm and 4.25±0.51 mm, respectively, in the PB group and 3.54±0.44 mm and 4.47±0.62 mm, respectively, in VR group. The distances between the VA lumen center and midline of the foramen magnum at the level of dural penetration was 10.4±1.13 mm in the PB group and 11.5±1.34 mm in the VR group (P>0.05). Conclusions VR technology can accurately simulate the anatomical features of the suboccipital vertebral arteries and their bony structures, which facilitates the planning of individual surgeries in the CVJ. PMID:24829084

Ha, Wenbo; Yang, DeLin; Gu, Shixin; Xu, Qi-Wu; Che, Xiaoming; Wu, Jin-Song; Li, Wensheng

2014-01-01

128

The relationship of transverse sinus stenosis to bony groove dimensions provides an insight into the aetiology of idiopathic intracranial hypertension  

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Transverse sinus tapered narrowings are frequently identified in patients with idiopathic intracranial hypertension (IIH); however, it remains unclear whether they are primary stenoses or whether they occur secondary to raised cerebrospinal fluid pressure. Computed tomographic venography demonstrates both the morphology of the venous system and the adjacent bony grooves so it may provide an insight into the aetiology of these transverse sinus stenoses. Tapered transverse sinus narrowings (>50%) were studied in 19 patients without IIH and 14 patients with IIH. Computed tomography vascular studies were reviewed and the dimensions of the venous sinuses and bony grooves at the sites of maximum and minimum transverse sinus area dimensions were recorded. There was demonstrated to be a strong correlation of bony groove height with venous sinus height at the largest portions of the transverse sinus in both IIH patients and non-IIH subjects as well as at the transverse sinus narrowing in non-IIH subjects. There was a discordant relationship between bony groove height and venous sinus height at the site of transverse sinus stenoses in IIH patients. In 5/23 IIH transverse sinus stenoses, the bony groove height was proportionate to that seen in non-IIH subjects. There were a further 8/23 cases where the small or absent sinus was associated with an absent bony groove. Transverse sinus tapered narrowings in subjects without IIH and in the majority of patients with IIH were associated with proportionately small or absent grooves, and these are postulated to be primary or fixed. Some patients with IIH demonstrate tapered transverse sinus stenoses with disproportionately large bony grooves, suggesting a secondary or acquired narrowing. This implies a varied aetiology for the transverse sinus stenoses of IIH. (orig.)

Connor, S.E.J.; Stewart, V.R.; O' Flynn, E.A.M. [King' s College Hospital, Neuroradiology Department, Ruskin Wing, London (United Kingdom); Siddiqui, M.A. [Southern General Hospital, Institute of Neurological Sciences, Glasgow (United Kingdom)

2008-12-15

129

The relationship of transverse sinus stenosis to bony groove dimensions provides an insight into the aetiology of idiopathic intracranial hypertension  

International Nuclear Information System (INIS)

Transverse sinus tapered narrowings are frequently identified in patients with idiopathic intracranial hypertension (IIH); however, it remains unclear whether they are primary stenoses or whether they occur secondary to raised cerebrospinal fluid pressure. Computed tomographic venography demonstrates both the morphology of the venous system and the adjacent bony grooves so it may provide an insight into the aetiology of these transverse sinus stenoses. Tapered transverse sinus narrowings (>50%) were studied in 19 patients without IIH and 14 patients with IIH. Computed tomography vascular studies were reviewed and the dimensions of the venous sinuses and bony grooves at the sites of maximum and minimum transverse sinus area dimensions were recorded. There was demonstrated to be a strong correlation of bony groove height with venous sinus height at the largest portions of the transverse sinus in both IIH patients and non-IIH subjects as well as at the transverse sinus narrowing in non-IIH subjects. There was a discordant relationship between bony groove height and venous sinus height at the site of transverse sinus stenoses in IIH patients. In 5/23 IIH transverse sinus stenoses, the bony groove height was proportionate to that seen in non-IIH subjects. There were a further 8/23 cases where the small or absent sinus was associated with an absent bony groove. Transverse sinus tapered narrowings in subjects without IIH and in the majority of patients with IIH were associated with proportionately small or absent grooves, and these are postulated to be primary or fixed. Some patients with IIH demonstrate tapered transverse sinus stenoses with disproportionately large bony grooves, suggesting a secondary or acquired narrowing. This implies a varied aetiology for the transverse sinus stenoses of IIH. (orig.)

2008-12-01

130

Ultrasonographic findings of soft tissue lesions in extremities  

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52 patients who had soft tissue lesions in extremity, buttock and shoulder,were studied by ultrasonography to evaluated the finding and significance of ultrasound study. The results were follows; 1. There were variable entities of diseases including 16 cases of Baker's cysts, 8 cases of abscesses, 8 cases of neoplasms, 4 case of hematomas and each case of joint effusion and bursitis, ganglion, thickening of soft tissue, muscle rupture and foreign body, respectively. 2. Baker's cyst was possibly diagnosis by characteristic site and finding with clinical history. 3. Abscess and hematoma showed hypoechoic or anechoic mass. Hematoma was easily diagnosed by associated findings with trauma, such as muscular swelling and rupture or bony fracture, but it was difficult to distinguish abscess from neoplasm due to similar finding. 4. Ultrasonography was a modality not only accurate for determining the presence, size and localization of lesion, but also easy for defining cyst or solid nature and relationship between lesion and adjacent structure

1989-02-01

131

Bony anatomic variants of the paranasal sinuses and nasal septum. Comparison between normal and chronic sinusitis  

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Agger nasi cells, concha bullosa, Haller's cells and deviation of the nasal septum were evaluated with coronal plane computerized tomographic (CT) scanning in patients with normal paranasal sinuses (44 cases) and patients with chronic sinusitis (91 cases). Agger nasi cells were present in 68 (50.4%) of cases. Concha bullosa was present in 39 cases (28.9%), Haller's cells were present in 15 cases (11.1%), and deviation of the nasal septum was present in 64 cases (47.4%). Haller's cells were more commonly encountered in cases with normal paranasal sinuses (20.5%), than in cases with chronic sinusitis (6.6%). Other bony structural variations were noted at a similar frequency in both groups. Each sinus (frontal sinus, ethmoid sinus, maxillary sinus and sphenoid sinus) of patients with chronic sinusitis was then evaluated separately. Agger nasi cells were observed more frequently in chronic frontal sinusitis and ethmoid sinusitis compared to subjects with normal sinuses. Concha bullosa was observed more frequently in cases with normal frontal sinuses and ethmoid sinuses than in cases of chronic frontal sinusitis and ethmoid sinusitis. Haller's cells and deviation of the nasal septum were observed at a similar frequency in both groups. Based on these results, it was thought that these bony structural variations sometimes disturbed the reopening of the normal ventilation and drainage pathways of the paranasal sinuses at the stage of acute sinusitis. These nasal ventilatory disturbances may predispose the patient to recurrent sinusitis, and may finally result in chronic sinusitis. (author)

1996-03-01

132

Bony manifestation of rickets in a sunny city - a case report from Yazd, Iran  

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Full Text Available Rickets is disease that occurs in growing bones in which defective mineralization occurs in both the bone and the cartilage of the epiphyseal growth plate, resulting in the retardation of growth and skeletal deformities. Rickets is more common in areas with less sunlight. However, this case report presents a case of the bony manifestation of rickets with the intake of vitamin D supplements in Yazd, a city in central Iran that has sunshine almost every day. A patient was referred to an out-patient general pediatric clinic for deformities of the legs and growth disturbance, with his height far below the normal range. The changes that were most evident in his X-rays were the bowing of the long bones of the legs and forearms and the cupping of the wrist metaphyseal region. In summary, we present a patient with bony manifestation of rickets despite living in a sunny area and taking vitamin D supplements. Thus, it is important to remember that rickets is still a common disease among children in Iran. More studies of this issue should be conducted, including the identification of abnormal cases and rescheduling vitamin D supplementation programs.

Mohammadhosain Afrand

2014-01-01

133

Sexual dimorphism of the bony labyrinth: a new age-independent method.  

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Currently in physical anthropology there is a need for reliable methods of sex estimation for immature individuals and highly fragmented remains. This study develops a sex estimation technique from discriminant function analysis of the bony labyrinth as it matures before puberty and can survive taphonomic conditions that would destroy most other skeletal material. The bony labyrinth contains the organs of hearing and balance. For this reason biologists and paleoanthropologists have undertaken research in this area to understand evolutionary changes in locomotion. Prior studies have found clear differences between species, but within-species variation has not been satisfactorily investigated. 3D segmentations of the left and right labyrinths of 94 individuals from a Cretan collection were generated and measured. Mean measurements of height, width, size, and shape indices were analyzed for sexual dimorphism, bilateral asymmetry, and measurement error. Significant sexual dimorphism was detected for several measurements. For sex estimation, the single best variable was the radius of curvature of the posterior semicircular canal, which achieved 76% accuracy. Two multivariate functions increased accuracy to 84%. Although these equations are less accurate than equations for complete long bones and crania, they appear to be as accurate as or better than other techniques for sexing immature individuals and temporal bones. PMID:23640711

Osipov, Benjamin; Harvati, Katerina; Nathena, Despoina; Spanakis, Konstantinos; Karantanas, Apostolos; Kranioti, Elena F

2013-06-01

134

Management of Extensive Maxillofacial Trauma With Bony Foreign Body Within the Orbit From a Chainsaw Injury  

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Objective: The goal of this case report is to characterize injury patterns typical for chainsaw injuries to the face. We describe our approach to the soft tissue and skeletal injury patterns seen in these injuries. Methods: We present a case report of a traumatic chainsaw injury to the face. Results: A literature review of the typical injury patterns seen in chainsaw injuries to the face is discussed. Fractures to the bony orbit are on of the most common findings. Traumatic orbital fractures are often associated with other facial fractures, including those of the maxillary sinus and naso-orbital-ethmoid (NOE) region. There is a reported 47% incidence of lacrimal obstruction after NOE fractures, most caused by bone malposition or damage to the lacrimal sac or duct. Misdiagnosis of this injury pattern can lead to chronic patient morbidity. Conclusion: We present a case of traumatic orbital fracture with subsequent bony intrusion into the orbit, necessitating urgent exploration. The compound soft tissue and skeletal injury in this patient is typical for patients with associated lacrimal injury. Awareness of the injury patterns and treatment algorithms of these cases allows for appropriate assessment and intervention.

Craft, Randall O.; Eberlin, Kyle R.; Stella, Michael H.; Caterson, Edward J.

2011-01-01

135

Multi-locus phylogenetic analysis reveals the pattern and tempo of bony fish evolution.  

Science.gov (United States)

Over half of all vertebrates are "fishes", which exhibit enormous diversity in morphology, physiology, behavior, reproductive biology, and ecology. Investigation of fundamental areas of vertebrate biology depend critically on a robust phylogeny of fishes, yet evolutionary relationships among the major actinopterygian and sarcopterygian lineages have not been conclusively resolved. Although a consensus phylogeny of teleosts has been emerging recently, it has been based on analyses of various subsets of actinopterygian taxa, but not on a full sample of all bony fishes. Here we conducted a comprehensive phylogenetic study on a broad taxonomic sample of 61 actinopterygian and sarcopterygian lineages (with a chondrichthyan outgroup) using a molecular data set of 21 independent loci. These data yielded a resolved phylogenetic hypothesis for extant Osteichthyes, including 1) reciprocally monophyletic Sarcopterygii and Actinopterygii, as currently understood, with polypteriforms as the first diverging lineage within Actinopterygii; 2) a monophyletic group containing gars and bowfin (= Holostei) as sister group to teleosts; and 3) the earliest diverging lineage among teleosts being Elopomorpha, rather than Osteoglossomorpha. Relaxed-clock dating analysis employing a set of 24 newly applied fossil calibrations reveals divergence times that are more consistent with paleontological estimates than previous studies. Establishing a new phylogenetic pattern with accurate divergence dates for bony fishes illustrates several areas where the fossil record is incomplete and provides critical new insights on diversification of this important vertebrate group. PMID:23788273

Broughton, Richard E; Betancur-R, Ricardo; Li, Chenhong; Arratia, Gloria; Ortí, Guillermo

2013-01-01

136

Aluminosilicates and biphasic HA-TCP composites: studies of properties for bony filling  

International Nuclear Information System (INIS)

Aluminosilicate materials synthesized at room temperature present good mechanical properties. Hydroxyapatite, tricalcicium phosphate or both offer a high biocompatibility in the biomedical field. In this work, we focused on the composites resulting from associations of these materials. The best compromise between porosity and biomechanical properties versus different parameters was determined. The in vitro behaviour of compounds in contact with the simulated body fluid (SBF) was studied and in vivo experiments in a rabbit's thighbones were carried out. The inductively coupled plasma-optical emission spectroscopy (ICP-OES) method permitted us to study the eventual release of Al from composites to SBF and to evaluate the chemical stability of composites characterized by the succession of SiO4 and AlO4 tetrahedra. The kinetic biomineralization, the bioconsolidation and biological studies were made. The results obtained show the chemical stability of composites. In the bone-implant interface, the intimate links reveal the high quality of the biointegration and the bioconsolidation between composites and bony matrix. Histological studies confirm good bony bonding and highlight the total absence of inflammation or fibrous tissues

2007-03-01

137

[Benign vocal fold lesions].  

Science.gov (United States)

Benign vocal fold lesions are grouped in lesions arising from the epithelium like papillomas, lesions affecting the Reinke's space (nodules, polyps, cysts, Reinkes's edema as a form of chronic laryngitis) and lesions affecting the arytenoid (granulomas). A multifactorial genesis is assumed. Main symptoms are dysphonia and hyperfunctional vocal behavior that might also be a cause of these lesions. PMID:23348959

Pickhard, A; Reiter, R

2013-05-01

138

The mammalian bony labyrinth reconsidered, introducing a comprehensive geometric morphometric approach.  

Science.gov (United States)

The bony labyrinth in the temporal bone houses the sensory systems of balance and hearing. While the overall structure of the semicircular canals and cochlea is similar across therian mammals, their detailed morphology varies even among closely related groups. As such, the shape of the labyrinth carries valuable functional and phylogenetic information. Here we introduce a new, semilandmark-based three-dimensional geometric morphometric approach to shape analysis of the labyrinth, as a major improvement upon previous metric studies based on linear measurements and angles. We first provide a detailed, step-by-step description of the measurement protocol. Subsequently, we test our approach using a geographically diverse sample of 50 recent modern humans and 30 chimpanzee specimens belonging to Pan troglodytes troglodytes and P. t. verus. Our measurement protocol can be applied to CT scans of different spatial resolutions because it primarily quantifies the midline skeleton of the bony labyrinth. Accurately locating the lumen centre of the semicircular canals and the cochlea is not affected by the partial volume and thresholding effects that can make the comparison of the outer border problematic. After virtually extracting the bony labyrinth from CT scans of the temporal bone, we computed its midline skeleton by thinning the encased volume. On the resulting medial axes of the semicircular canals and cochlea we placed a sequence of semilandmarks. After Procrustes superimposition, the shape coordinates were analysed using multivariate statistics. We found statistically significant shape differences between humans and chimpanzees which corroborate previous analyses of the labyrinth based on traditional measurements. As the geometric relationship among the semilandmark coordinates was preserved throughout the analysis, we were able to quantify and visualize even small-scale shape differences. Notably, our approach made it possible to detect and visualize subtle, yet statistically significant (P = 0.009), differences between two chimpanzee subspecies in the shape of their semicircular canals. The ability to discriminate labyrinth shape at the subspecies level demonstrates that the approach presented here has great potential in future taxonomic studies of fossil specimens. PMID:22404255

Gunz, Philipp; Ramsier, Marissa; Kuhrig, Melanie; Hublin, Jean-Jacques; Spoor, Fred

2012-06-01

139

Reconstruction of bony facial contour deficiencies with polymethylmethacrylate implants: case report  

Directory of Open Access Journals (Sweden)

Full Text Available Facial trauma can be considered one of the most serious aggressions found in the medical centers due to the emotional consequences and the possibility of deformity. In craniofacial surgery, the use of autologous bone is still the first choice for reconstructing bony defects or irregularities. When there is a shortage of donor bone or a patient refuses an intracranial operation, alloplastic materials such as polymethylmethacrylate (PMMA can be used. The PMMA prosthesis can be pre-fabricated, bringing advantages such as reduction of surgical time, easy technical handling and good esthetic results. This paper describes the procedures for rehabilitating a patient with PMMA implants in the region of the face, recovering the facial contours and esthetics of the patient.

Ruy C. C. Abdo Filho

2011-08-01

140

Reconstruction of bony facial contour deficiencies with polymethylmethacrylate implants: case report  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in english Facial trauma can be considered one of the most serious aggressions found in the medical centers due to the emotional consequences and the possibility of deformity. In craniofacial surgery, the use of autologous bone is still the first choice for reconstructing bony defects or irregularities. When t [...] here is a shortage of donor bone or a patient refuses an intracranial operation, alloplastic materials such as polymethylmethacrylate (PMMA) can be used. The PMMA prosthesis can be pre-fabricated, bringing advantages such as reduction of surgical time, easy technical handling and good esthetic results. This paper describes the procedures for rehabilitating a patient with PMMA implants in the region of the face, recovering the facial contours and esthetics of the patient.

Abdo Filho, Ruy C. C.; Oliveira, Thais M.; Lourenço Neto, Natalino; Gurgel, Carla; Abdo, Ruy C.C..

 
 
 
 
141

Crouzon syndrome with bony upper airway obstruction: case report and review literature.  

Science.gov (United States)

Crouzon syndrome is a rare genetic disorder. It is inherited as an autosomal dominant pattern. Mutations in the FGFR2 gene are known to cause Crouzon syndrome. Craniofacial abnormalities are common at birth and may progress with time. The severity of these signs and symptoms varies among affected children. A full term, large for date, male baby was delivered to a gravida 2 mother by cesarean section having facial dimorphism suggestive of Crouzon syndrome. Genetic team confirmed the diagnosis. Baby had severe respiratory distress. On work up, upper bony airway narrowing was found (diameter 3 mm). Later on, baby was operated for the same. Baby is asymptomatic now and doing well up to 2 months of follow-up. Management of Crouzon disease is multidisciplinary and early diagnosis has prime importance. Follow-up must ensure late features like hearing problems, vision problems, dental problems, intelligence, cranial synostosis, and upper airway problems. PMID:24828762

Gothwal, Sunil; Nayan, Swati; Kumar, Jagdish

2014-08-01

142

Bony Metaplasia associated with the delay in the ulcer healing in diabetic patient . A case study  

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Full Text Available This search aims to describe the bony metaplasia found in the histopathological analysis of ulcer in patients observed at the Wound Repair Aid Center at the university hospital. The study is part of a search project applied in CNPq entitled “Delay in the cutaneous ulcers healing: clinical and morphological sectional evaluation”, being that during the blades analysis we found out cells that performed different from the osteoblasts. It is about a study of case of a diabetes and chronic renal patient with bad piercing planting. The data collect was based on the instrument of search with clinical and descriptive identification data about the hurt, besides the material for the pathological study histopathological. The morphological result indicates the difference of mesenchymals cells in osteoblasts in the injury, instead of fibroblasts. It can be concluded that the chronicity in the wound made one type of cell to be replaced by another type impairing the scarring

Beatriz Guitton Oliveira

2007-01-01

143

Bony anatomic variants of the paranasal sinuses and nasal septum. Comparison between normal and chronic sinusitis  

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Agger nasi cells, concha bullosa, Haller`s cells and deviation of the nasal septum were evaluated with coronal plane computerized tomographic (CT) scanning in patients with normal paranasal sinuses (44 cases) and patients with chronic sinusitis (91 cases). Agger nasi cells were present in 68 (50.4%) of cases. Concha bullosa was present in 39 cases (28.9%), Haller`s cells were present in 15 cases (11.1%), and deviation of the nasal septum was present in 64 cases (47.4%). Haller`s cells were more commonly encountered in cases with normal paranasal sinuses (20.5%), than in cases with chronic sinusitis (6.6%). Other bony structural variations were noted at a similar frequency in both groups. Each sinus (frontal sinus, ethmoid sinus, maxillary sinus and sphenoid sinus) of patients with chronic sinusitis was then evaluated separately. Agger nasi cells were observed more frequently in chronic frontal sinusitis and ethmoid sinusitis compared to subjects with normal sinuses. Concha bullosa was observed more frequently in cases with normal frontal sinuses and ethmoid sinuses than in cases of chronic frontal sinusitis and ethmoid sinusitis. Haller`s cells and deviation of the nasal septum were observed at a similar frequency in both groups. Based on these results, it was thought that these bony structural variations sometimes disturbed the reopening of the normal ventilation and drainage pathways of the paranasal sinuses at the stage of acute sinusitis. These nasal ventilatory disturbances may predispose the patient to recurrent sinusitis, and may finally result in chronic sinusitis. (author).

Ikeda, Motohisa [Soka Municipal Hospital, Saitama (Japan); Watanabe, Isamu

1996-03-01

144

Skin thickness on bony prominences measured by ultrasonography in patients with spinal cord injury  

Science.gov (United States)

Objective The detailed assessment of soft tissues over bony prominences and identification of methods of predicting pressure sores would improve the quality of care for patients with spinal cord injury (SCI). Comparing skin thicknesses on bony prominences in patients with SCI to those in healthy individuals will represent, to our knowledge, the first study aimed at determining whether differences in skin thicknesses between these groups can be detected by ultrasound. Design In both patients and controls, skin thicknesses on the sites at risk for pressure ulcers – sacrum, greater trochanter, and ischium – were evaluated using high-frequency ultrasound. The waist was also evaluated by the same method for control as it was considered to be a pressure-free region. Participants Thirty-two patients with complete thoracic SCI and 34 able-bodied individuals. Results The skin was significantly thinner over the sacrum and ischial tuberosity in individuals with SCI compared with healthy individuals. No significant differences were observed in skin thicknesses over the greater trochanter or the waist between the two groups. Conclusions Protecting skin integrity in patients with paraplegia is challenging due to many contributing factors, such as prolonged pressure, frictional/shearing forces, and poor nutrition. Thinning of the skin can increase the risk of soft tissue damage, leading to pressure ulcers. The significant differences in skin thickness at the sacrum and ischium provide the basis for establishing the early signs of pressure damage. Measuring skin thickness by ultrasound is a reliable non-invasive method that could be a promising tool for predicting pressure ulcers.

Yalcin, Elif; Akyuz, Mufit; Onder, Burcu; Unalan, Halil; Degirmenci, Ibrahim

2013-01-01

145

A clinico-radiologic study of bony remodeling of the fractured condyles in children  

International Nuclear Information System (INIS)

Bony remodeling pattern of condyle fractures in children are different from in adult for growing of condyle, also might affect treatment and prognosis of the condyle fracture. Subjects of this clinical and radiologic study were 26 temporomandibular joints diagnosed as condyle fracture in 23 patients under 15 years old age, They were treated with conservative method at Dental Hospital of Yonsei University from Jan., 1986 to Oct., 1994. Bony remodeling related with fracture pattern was evaluated. The results obtained are as follows: 1. The ratio of male to female in patients with condyle fracture was 1 : 0.9 and the difference of sex ratio was not noted. Comparing with preschool-age group and school-age group, age frequency was higher in preschool-age group (83%). 2. Fallen down (54%) was the most frequent cause of condyle fractures. Traffic accident and slip down were followed. 3. The most common clinical sign of condyle fractures was tenderness to palpation (19 cases). Mouth opening limitation (17 cases), swelling (7 cases), malocclusion (3 cases) were next in order. 4. According to sites of condyle fractures, unilateral fractures were in 20 patients and bilateral fractures in 3 patients, therefore total 23 patients-26 cases of condyle fracture were observed. According to fracture distribution, condyle fractures were in 10 patients (44%). Condyle fractures with symphysis fracture (9 patients, 39%), condyle fractures with ascending ramus fracture (2 patients, 9%), condyle fracture with mandibular body fracture (1 patient, 4%), and condyle fractures with mandibular angle fracture (1 patient, 4%) were followed. 5. In displacement pattern of fractured fragment of mandibular condyle, displacement (17 cases, 66%) was most common. Dislocation (5 cases, 19%) and deviation (4 cases, 15%) were next in order. 6. During the observation period of fractured condyles, remodeling patterns of fracture sites related with articular fossa were observed with usual congealer shape in 23 cases and with prominently different shape in 3 cases.

1995-08-01

146

On the CT-diagnosis of optic nerve lesions. Differential diagnostic criteria  

International Nuclear Information System (INIS)

Computed tomograms of 166 optic nerve lesions were analyzed: 97 were mainly orbital and 69 mainly intracranial. The criteria were clinical course, size, density and delineation of the optic nerve shadow, orbital and cerebral soft tissue abnormalities, and bony changes in the optic canal. Characteristic CT features are described of individual disease entities such as optic gliomas, optic nerve sheath meningiomas, neoplastic and inflammatory infiltrations. The differential diagnostic importance of individual CT criteria is evaluated and discussed. Simultaneous visualization of orbital and intracranial soft tissue changes as well as bony changes in the optic canal allow the location and identification of the majority of optic nerve lesions based on the criteria mentioned above, and optic nerve tumors can be differentiated. In 9 patients with optic neuritis due to clinically proven encephalitis and in 17 patients with total optic atrophy, no changes in the size of the optic nerve could be found. CT evaluation of the intraorbital portion of the optic nerve requires special examination techniques. Oblique computer reformations through the optic canal provide excellent visualization of bony changes in the optic canal. The exclusion of intracranial causes of optic nerve lesions requires intravenous injection of contrast material. (orig.)

1982-01-01

147

Distinct focal lesions of the femoral head: imaging features suggesting an atypical and minimal form of bone necrosis  

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Heading AbstractObjective. To document the imaging findings observed in patients with an unusual pattern of abnormality of the femoral head, most likely representing osteonecrosis.Design and patients. The imaging findings in 11 patients (10 men, 1 woman; age range 32-55 years) with a distinct lesion of the femoral head were reviewed with particular attention to the morphologic appearance, location, and extent of the lesion(s) in the proximal femur.Results. The 16 lesions identified in these patients extended to the subchondral area. Articular collapse was not evident in any hip. Radiography and CT showed areas of mixed bone sclerosis and osteolysis surrounded by sclerotic margins. On MR imaging, the signal intensity characteristics of the osseous lesion(s) were most commonly similar to those of fluid. Histopathologic findings, available in two hips, were typical of osteonecrosis. There was evidence of correlation of the site of the lesion with the known general distribution and anastomoses of arteries supplying the femoral head.Conclusion. A distinct, focal lesion of the femoral head is believed to represent an atypical form of bone necrosis. Its restriction to a small portion of the femoral head may relate to localized vascular anatomy. Recognition of the quite characteristic imaging findings can prevent misdiagnosis and may have implications for the prediction of the natural course of the disease. (orig.)

Theodorou, Daphne J. [Department of Radiology, School of Medicine, University of California, San Diego Medical Center, San Diego, California (United States); Department of Radiology, Veterans Administration Medical Center, San Diego, California (United States); Department of Radiology, Veterans Administration Medical Center, 3350 La Jolla Village Drive, San Diego, California 92161 (United States); Theodorou, Stavroula J.; Resnick, Donald [Department of Radiology, School of Medicine, University of California, San Diego Medical Center, San Diego, California (United States); Department of Radiology, Veterans Administration Medical Center, San Diego, California (United States); Haghighi, Parviz [Department of Pathology, Veterans Administration Medical Center, San Diego, California (United States)

2002-08-01

148

The effect of vitamin A supplementation on retinoic acid-related orphan receptor ?t (ROR?t) and interleukin-17 (IL-17) gene expression in Avonex-treated multiple sclerotic patients.  

Science.gov (United States)

The aim of this study was to investigate the role of vitamin A on ROR?t and IL-17 gene expression in multiple sclerotic patients. Patients in the vitamin A group received 25,000 IU retinyl palmitate per day, while patients in the placebo group took one capsule of placebo per day for 6 months. Gene expression was measured by real-time PCR at the first and end of the study. The results of this study show that vitamin A downregulates IL-17 and ROR?t gene expression. No changes in gene expression occurred in the placebo group. PMID:23868508

Mohammadzadeh Honarvar, Niyaz; Harirchian, Mohammad Hossein; Koohdani, Fariba; Siassi, Feridoun; Abdolahi, Mina; Bitarafan, Sama; Salehi, Eisa; Sahraian, Mohammad Ali; Eshraghian, Mohammad Reza; Saboor-Yarghi, Ali Akbar

2013-11-01

149

Spinal metastatic lesion in cancer patients. Investigation based on statistical analysis by bone scintigrams  

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In a series of 2,216 cancer patients undergoing bone scintigraphy after diagnosis of the primary malignant tumor, 558 (25.2%) were found to have abnormal vertebral accumulation of radioactivity during the clinical course. Abnormal radioactivity in the vertebrae was frequently noted in patients with prostatic and renal cancer. The lumbar vertebrae were the most frequent sites but the cervical vertebrae were also affected with prostatic cancer, the thoracic vertebrae with lung and prostatic cancer, the lumbar vertebrae with breast and prostatic cancer and the sacral vertebrae with uterine cervical and prostatic cancer. Of the 558 patients with abnormal spinal radioactivity, 221 were examined by CT scan; the accumulated radioactivity was identified as a metastatic lesion in 170 patients (76.9%). Abnormal radioactivity was identified as a metastatic lesion most often in lung cancer patients. The CT-diagnosed metastases were classified into 3 types: sclerotic (51 patients, 30.0%), osteolytic (112, 65.9%), and mixed (46, 27.1%). The sclerotic type was relatively frequent in uterine cervical cancer, less frequent in lung cancer, and not seen in head and neck or renal cancer patients. The osteolytic type was relatively frequent in lung and renal cancer and less frequent in uterine cervical and prostatic cancer patients. Of the patients with CT-diagnosed vertebral metastasis, 87.3% survived for 3 months and 66.2% for 6 months after the detection of abnormal bone scintigraphy. Survival was shorter in patients with lung or gastrointestinal cancer than in those with other types of tumors. Since the pathology of vertebral metastasis of malignant tumors differs according to the primary lesion, the metastatic nature must be considered in the choice of treatment. (author).

Inoue, Takashi [Osaka Medical Coll., Takatsuki (Japan)

1995-12-01

150

Description of patients with bony tumors treated with prosthesis in reconstruction in the Servicio de Ortopedia at the Hospital Rafael Angel Calderon Guardia 2000-2006  

International Nuclear Information System (INIS)

The use of prosthesis in reconstruction for the management of extensive tumor bone lesions. The study of six patients treated is performed at the Hospital Rafael Angel Calderon Guardia, who were treated for aggressive tumors in the period 2001-2006. Bony tumors are conceptualized, as well as fundamental aspects of cell biology in its development and the classification of the same. Also, relevant information is included with relation to the most frequent indications and possible treatments. In all six cases was placed the rescue prosthesis, four of them has been obtained excellent results. Limb amputation has been the only alternative until the decade of the 70 and survival rates with this treatment were 10 to 20% survival at 5 years. Today, with advances in chemotherapy and limb salvage prosthesis, patients without metastases at diagnosis have a survival of 65 to 75% at five years. The study has made it possible to simultaneously to analyze some aspects of care to these patients; such as: time of biopsy, time of diagnosis, time of initiation of chemotherapy and surgical intervention time. Through this study has concluded that when referring to a malignant tumor of bone is absolutely essential that the process of diagnosis and initiation of treatment of limb salvage surgery are addressed as soon as possible. Finally, some recommendations are raised to strengthen the treatment of malignant tumors in the Hospital Rafael Angel Calderon Guardia. (author)

2007-01-01

151

A dose-response relationship for time to bone pain resolution after stereotactic body radiotherapy (SBRT) for renal cell carcinoma (RCC) bony metastases  

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Background. To investigate the utility of stereotactic body radiotherapy (SBRT) in the treatment of painful renal cell carcinoma (RCC) bone metastases, and for a possible dose effect on time to symptom relief. Material and methods. Eighteen patients with 24 painful osseous lesions from metastatic RCC were treated with SBRT. The most common treatment regimens were 24 Gy in 3 fractions and 40 Gy in 5 fractions. The times from treatment to first reported pain relief and time to symptom recurrence were evaluated. Median follow-up was 38 weeks (1-156 weeks). Results. Seventy-eight percent of all patients had pain relief. Patients treated with a BED > 85 Gy achieved faster and more durable pain relief compared to those treated with a BED < 85 Gy. There was decrease in time to pain relief after a change in treatment regimen to 8 Gy x 5 fractions (BED = 86). There was only one patient with grade 1 skin toxicity. No neurological or other toxicity was observed. Conclusions. SBRT can safely and effectively treat painful RCC bony metastases. There appears to be a relationship between radiation dose and time to stable pain relief.

Jhaveri, Pavan M. [Dept. of Radiology, Section of Radiation Oncology, Baylor College of Medicine, Houston (United States); Teh, Bin S.; Paulino, Arnold C.; Blanco, Angel I.; Butler, E. Brian [Dept. of Radiation Oncology, The Methodist Hospital/The Methodist Hospital Research Inst., Houston (United States)], email: bteh@tmhs.org; Lo, Simon S. [Dept. of Radiation Oncology, Univ. Hospitals Seidman Cancer Center, Case Western Reserve Univ., Cleveland (United States); Amato, Robert J. [Dept. of Internal Medicine, Div. of Oncology, Univ. of Texas Health Sciences Center, Houston (United States)

2012-05-15

152

Quantitative computed tomography as a test of endurance for evaluation of bony plates; Utilizacao da tomografia computadorizada quantitativa como teste de resistencia para avaliacao de placas osseas  

Energy Technology Data Exchange (ETDEWEB)

Quantitative computed tomography was used to determine the radiodensity of bony plates. The CT scans provided information regarding radiodensity of bony plates and allowed to verify the uniformity of bone mineral density in their scope. The proposed methodology should be considered as another tool for determining the resistance of these biomaterials. (author)

Melo Filho, E.V.; Costa, L.A.V.S.; Oliveira, D.C. [Universidade Federal do Parana (UFPR), Curitiba, PR (Brazil); Freitas, P.M.C. [Escola de Veterinaria - Universidade Federal de Minas Gerais - Belo Horizonte, MG (Brazil); Teixeira, M.W.; Costa, F.S. [Universidade Federal Rural de Pernambuco - Recife, PE (Brazil)

2012-06-15

153

CT of the canine lumbosacral spine in extension - flexion rotation; part I: bony window  

International Nuclear Information System (INIS)

The canine lumbosacral spine is examined radiographically in extended and flexed lateral position as well as ventrodorsally. Superimposition of bones hinders exact evaluation of the lumbosacral intervertebral foramen in case of cauda equina syndrome, especially when degenerative changes overlap. CT or MRI are more and more indicated to get reliable findings because myelography is not always of diagnostic value. For this study twelve dogs (7 German Shepherd dogs, 4 Cross-breds, and 1 Rottweiler) of different age and sex were taken which had been referred for CT examination of the lumbosacral area. Plain radiographs did not show abnormalities. The anaesthetized dogs were positioned in dorsal recumbency with the legs firstly extended and secondly flexed according to flexion-extension radiography. Slice thickness was 2 mm, the CT images were evaluated in both bony and soft tissue windows. Bony window easily showed vertebral bodies, vertebral canal, pedicles, vertebral laminae, and articular processes of L7 and S1. Median height of the vertebral canal did not change during extension or flexion at the level of L7 and the sacrum. Height and width of the intervertebral foramen and width of the interarcual foramen changed markedly from extension to flexion. Lateral recessus of the vertebral canal always could be observed as ventrolateral widening. In sagittal CT scans of the lumbosacral specimen of a normal German Shepherd dog cranial articular processes of the sacrum were detected to be responsible for maximum height or width of the intervertebral foramen. Evolving from the lateral recessus the intervertebral foramen was initially oval-shaped and got rounded and narrowed by the cranial articular process of the sacrum. Position and shape of the cranial articular processes of the sacrum were evaluated. Surface of the cranial articular processes of S1 were found even with articular spaces congruent, but some also appeared slightly concave or convex where incongruity of the joint space was present. Most of the dogs showed angles about 45 degrees, but some had 60 or 35 degrees and were classified steep or plane, respectively. Soft tissue formations such as intervertebral disk, ligaments, vessels, and nerves will be described in part II of this study. (author)

2002-01-01

154

Orbital Tumors Excision without Bony Marginotomy under Local and General Anesthesia  

Science.gov (United States)

To present our experience of removing middle to deep orbital tumors using a combination of minimally invasive soft tissue approaches, sometimes under local anesthesia. Methods. In this retrospective case series, 30 patients (13 males and 17 females) underwent tumor removal through eyelid crease (17 eyes), conjunctival (nine eyes), lateral canthal (two eyes), and transcaruncular (two eyes) approaches. All tumors were located in the posterior half of the orbit. Six cases were removed under monitored anesthesia care with local block, and 24 were under general anesthesia. Results. The median (range) age and follow-up duration were 48.5 (31–87) years old and 24.5 (4–375) weeks, respectively. Visual acuity and ocular motility showed improvement or no significant change in all but one patient at the latest followup. Confirmed pathologies revealed cavernous hemangioma (15 cases), pleomorphic adenoma (5 cases), solitary fibrous tumor (4 cases), neurofibroma (2 cases), schwannoma (2 cases), and orbital varix (1 case). None of the patients experienced recurrence. Conclusions. Creating a bony marginotomy increases intraoperative exposure of the deep orbit but adds substantial time and morbidity. Benign orbital tumors can often be removed safely through small soft-tissue incisions, without bone removal and under local anesthesia.

Goldberg, Robert A.; Rootman, Daniel B.; Nassiri, Nariman; Samimi, David B.; Shadpour, Joseph M.

2014-01-01

155

Wyst?powanie grzybów w ontocenozie jamy ustnej a zmiany b?ony ?luzowej  

Directory of Open Access Journals (Sweden)

Full Text Available Wst?p: W pracy na podstawie w?asnych bada? klinicznych przedstawiono gatunki grzybów wyst?puj?cych u osób z niektórymi zmianami w przyz?biu i b?onie ?luzowej. Materia? i metody: Badaniom poddano 196 pacjentów, u których wyizolowano szczepy grzybów. Dla wszystkich osób opracowano ankiet? zawieraj?c? dane badania podmiotowego i przedmiotowego. Wyniki: W?ród 196 osób u 22 rozpoznano gingMtis, u 31 - glossitis, u 27 - leukoplaki?, u 27 - periodontitis adults, a u 21 - periodontitis juvenilis, u 33 - stomatitis prothetica, a u 35 - stomatitis atrophica. Wykryte grzyby zakwalifikowano do 8 gatunków rodzaju Candida, a mianowicie: Candida albicans - 146 szczepów, Candida tropicalis - 18 (9,2%, Candida krusei - 10 (5,1%, Candida guilliermondii - 6 (3,1%, Candida parapsilosis - 3 (1,5%, Candida kefyr - 6 (3,1%, Candida famata - 5 (2,6%, Candida zeylanoides - 2 (1,0%. Wnioski: Stwierdzono zale?no?? statystycznie istotn? mi?dzy obecno?ci? grzybów a niektórymi objawami podmiotowymi i przedmiotowymi. Najwi?ksz? liczb? gatunków grzybów wykryto u osób z rozpoznaniem periodontitis juvenile.

Anna J. Kurnatowska

2003-12-01

156

Automated bony region identification using artificial neural networks: reliability and validation measurements  

International Nuclear Information System (INIS)

The objective was to develop tools for automating the identification of bony structures, to assess the reliability of this technique against manual raters, and to validate the resulting regions of interest against physical surface scans obtained from the same specimen. Artificial intelligence-based algorithms have been used for image segmentation, specifically artificial neural networks (ANNs). For this study, an ANN was created and trained to identify the phalanges of the human hand. The relative overlap between the ANN and a manual tracer was 0.87, 0.82, and 0.76, for the proximal, middle, and distal index phalanx bones respectively. Compared with the physical surface scans, the ANN-generated surface representations differed on average by 0.35 mm, 0.29 mm, and 0.40 mm for the proximal, middle, and distal phalanges respectively. Furthermore, the ANN proved to segment the structures in less than one-tenth of the time required by a manual rater. The ANN has proven to be a reliable and valid means of segmenting the phalanx bones from CT images. Employing automated methods such as the ANN for segmentation, eliminates the likelihood of rater drift and inter-rater variability. Automated methods also decrease the amount of time and manual effort required to extract the data of interest, thereby making the feasibility of patient-specific modeling a reality. (orig.)

2008-04-01

157

In vivo hip joint contact distribution and bony impingement in normal and dysplastic human hips.  

Science.gov (United States)

Our objectives were to clarify the 3D articular contact areas of the in vivo normal hip joint and acetabular dysplasia during specific positions using magnetic resonance imaging (MRI), voxel-based registration, and proximity mapping. Forty-two normal and 24 dysplastic hips were examined. MRI was performed at four positions: neutral; 45° flexion; 15° extension; and the Patrick position. Femur and pelvis bone models were reconstructed at the neutral position and superimposed over the images of each different position using voxel-based registration. The inferred cartilage contact and bony impingement were investigated using proximity mapping. The femoral head translated in the anterior or posteroinferior, anterosuperior, and posteroinferior direction from neutral to 45° flexion, 15° extension, and the Patrick position, respectively. Multiple regression analyses showed age, femoral head sphericity, and acetabular sphericity to be associated with higher hip instability. The present technique using subject-specific models revealed the in vivo hip joint contact area in a population of healthy individuals and dysplastic patients without radioactive exposure. These results can be used for analyzing disease progression in the dysplastic hip and pathogenesis of acetabular labral tear. PMID:23804572

Akiyama, Keisuke; Sakai, Takashi; Koyanagi, Junichiro; Yoshikawa, Hideki; Sugamoto, Kazuomi

2013-10-01

158

Arthroscopic Repair of "Peel-Off" Lesion of the Posterior Cruciate Ligament at the Femoral Condyle  

Science.gov (United States)

Posterior cruciate ligament (PCL) injuries are uncommon, and most occur in association with other lesions. The treatment of PCL injuries remains controversial; in addition, PCL injuries have been documented to have a propensity to heal. In the literature several different patterns of PCL injury have been described including midsubstance tears/injuries, tibial bony avulsions, femoral bony avulsions, and femoral “peel-off” injuries. A peel-off injury is a complete or incomplete soft-tissue disruption of the PCL at its femoral attachment site without associated bony avulsion. In recent years arthroscopic repair of femoral avulsion and peel-off lesions of the PCL has been reported. In most of these articles, a transosseous repair with sutures passed through 2 bone tunnels into the medial femoral condyle has been described. We present a case of a femoral PCL avulsion in a 20-year-old collegiate football player with an associated medial collateral ligament injury, and we report about a novel technique for PCL repair using 2 No. 2 FiberWire sutures and two 2.9-mm PushLock anchors (Arthrex) to secure tensioning the ligament at its footprint.

Rosso, Federica; Bisicchia, Salvatore; Amendola, Annunziato

2014-01-01

159

Arthroscopic repair of "peel-off" lesion of the posterior cruciate ligament at the femoral condyle.  

Science.gov (United States)

Posterior cruciate ligament (PCL) injuries are uncommon, and most occur in association with other lesions. The treatment of PCL injuries remains controversial; in addition, PCL injuries have been documented to have a propensity to heal. In the literature several different patterns of PCL injury have been described including midsubstance tears/injuries, tibial bony avulsions, femoral bony avulsions, and femoral "peel-off" injuries. A peel-off injury is a complete or incomplete soft-tissue disruption of the PCL at its femoral attachment site without associated bony avulsion. In recent years arthroscopic repair of femoral avulsion and peel-off lesions of the PCL has been reported. In most of these articles, a transosseous repair with sutures passed through 2 bone tunnels into the medial femoral condyle has been described. We present a case of a femoral PCL avulsion in a 20-year-old collegiate football player with an associated medial collateral ligament injury, and we report about a novel technique for PCL repair using 2 No. 2 FiberWire sutures and two 2.9-mm PushLock anchors (Arthrex) to secure tensioning the ligament at its footprint. PMID:24749037

Rosso, Federica; Bisicchia, Salvatore; Amendola, Annunziato

2014-02-01

160

Trifocal distraction-compression osteosynthesis in conjunction with passive self-ligating brackets for the reconstruction of a large bony defect and multiple missing teeth.  

Science.gov (United States)

Reconstruction of a maxillary dentoalveolar defect and closure of a wide oronasal fistula in a patient with a traumatic injury are challenging for both orthodontists and surgeons. A conventional bone graft is used to fill the alveolar bone defect, to restore continuity between bony segments, and to provide bony support for tooth eruption adjacent to the defect or for orthodontic tooth movement into the bony defect. However, if the defect is too large to allow for a conventional bone graft, transport distraction osteogenesis can be used for reconstruction of the alveolar bone and implant placement. However, there is usually a discrepancy in the movement rates between the bony segment and the teeth. Passive self-ligating brackets can minimize friction between the bracket and the archwire; therefore, the rate of tooth movement can be balanced with that of the bony segment. By using orthodontic miniscrew and elastomeric traction, the regenerated bony segments can be bent to form a curved arch in the alveolar bone. In the treatment reported here, trifocal distraction-compression osteosynthesis with orthodontic miniscrews and passive self-ligating brackets helped establish bone continuity in a bony defect area, created anterior curvature of the alveolar bone, and provided good-quality regenerated bone for implant placement. PMID:18405825

Baek, Seung-Hak; Kim, Na-Young; Paeng, Jun-Young; Kim, Myung-Jin

2008-04-01

 
 
 
 
161

Two-year clinical evaluation of three adhesive systems in non-carious cervical lesions  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in english OBJECTIVES: Adhesive systems are continuously being introduced to Dentistry, unfortunately often without sufficient clinical validation. The aim of this study was to evaluate the clinical performance of cervical restorations done with three different adhesive systems. MATERIAL AND METHODS: 158 non-c [...] arious cervical lesions of 23 patients were restored with a nanofilled composite resin (Filtek Supreme, 3M/ESPE) combined with Single Bond (3M/ESPE, group SI), Clearfil SE (Kuraray Medical Inc., group CL) and Xeno III (De Trey Dentsply, group XE). In groups SI-B, CL-B and XE-B, the outer surface of the sclerotic dentin was removed by roughening with a diamond bur before application of the respective adhesive systems. In groups CL-BP and XE-BP, after removal of the outer surface of the sclerotic dentin with the bur, the remaining dentin was etched with 37% phosphoric acid and the self-etch adhesive systems Clearfil SE and Xeno III were applied, respectively. Lesions were evaluated at baseline, and restorations after 3 months, 1 year and 2 years using modified USPHS criteria. RESULTS: After 2 years, no significant difference was found between the retention rates of the groups (p >0.05). Although groups CL and SI showed significantly better marginal adaptation than group XE (p0.05). After 2 years no significant difference was observed among the marginal staining results of all groups (p>0.05). CONCLUSION: Although all adhesive systems showed similar retention rates, Clearfil SE and Single Bond showed better marginal adaptation than Xeno III after 2 years of follow-up.

Evrim Eliguzeloglu, Dalkilic; Huma, Omurlu.

162

Two-year clinical evaluation of three adhesive systems in non-carious cervical lesions  

Directory of Open Access Journals (Sweden)

Full Text Available OBJECTIVES: Adhesive systems are continuously being introduced to Dentistry, unfortunately often without sufficient clinical validation. The aim of this study was to evaluate the clinical performance of cervical restorations done with three different adhesive systems. MATERIAL AND METHODS: 158 non-carious cervical lesions of 23 patients were restored with a nanofilled composite resin (Filtek Supreme, 3M/ESPE combined with Single Bond (3M/ESPE, group SI, Clearfil SE (Kuraray Medical Inc., group CL and Xeno III (De Trey Dentsply, group XE. In groups SI-B, CL-B and XE-B, the outer surface of the sclerotic dentin was removed by roughening with a diamond bur before application of the respective adhesive systems. In groups CL-BP and XE-BP, after removal of the outer surface of the sclerotic dentin with the bur, the remaining dentin was etched with 37% phosphoric acid and the self-etch adhesive systems Clearfil SE and Xeno III were applied, respectively. Lesions were evaluated at baseline, and restorations after 3 months, 1 year and 2 years using modified USPHS criteria. RESULTS: After 2 years, no significant difference was found between the retention rates of the groups (p >0.05. Although groups CL and SI showed significantly better marginal adaptation than group XE (p0.05. After 2 years no significant difference was observed among the marginal staining results of all groups (p>0.05. CONCLUSION: Although all adhesive systems showed similar retention rates, Clearfil SE and Single Bond showed better marginal adaptation than Xeno III after 2 years of follow-up.

Evrim Eliguzeloglu Dalkilic

2012-04-01

163

An osseous lesion in a 10-year-old boy with Hodgkin's lymphoma: a case report  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Introduction Osseous involvement of Hodgkin's lymphoma is uncommon. When osteolytic lesions are seen on imaging it is important to evaluate potential other causes. Case presentation We report the case of a 10-year-old Caucasian boy who presented to our facility with a bony lesion of the right clavicle and enlarged cervical lymph nodes. A simultaneous biopsy of the lymph node and of the osteolytic process of his right proximal clavicle was performed and revealed two different kinds of lesions: a mixed cellularity Hodgkin's lymphoma and an osteochondroma. Conclusions Since the latter is a common benign bone tumor, which should not interfere with the staging of the lymphoma, we emphasize the importance of ensuring that all efforts are made to acquire a diagnostic biopsy of all atypical lesions.

Moser Asher

2011-10-01

164

Crystal Structure of a Bony Fish ?2-Microglobulin: INSIGHTS INTO THE EVOLUTIONARY ORIGIN OF IMMUNOGLOBULIN SUPERFAMILY CONSTANT MOLECULES*  

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Three-dimensional structures of ?2-microglobulin (?2m) from chicken and various mammals have been described previously, but aside from genomic sequences, very little is known about the three-dimensional structures of ?2m in species other than warm-blooded vertebrates. Here, we present the first three-dimensional structure of ?2m from bony fish grass carp (Ctid-?2m), resolved at 2.1 ?. The key structural differences between this new structure and previously published structures are two ...

Chen, Weihong; Gao, Feng; Chu, Fuliang; Zhang, Jianhua; Gao, George F.; Xia, Chun

2010-01-01

165

Humeral avulsion of the anterior band of the inferior glenohumeral ligament with associated subscapularis bony avulsion in skeletally immature patients  

International Nuclear Information System (INIS)

Objective: We describe the imaging appearances of an injury complex occurring in the skeletally immature patient consisting of an avulsion fracture of the subscapularis attachment to the lesser tuberosity and avulsion of the inferior glenohumeral ligament (HAGL) which in two cases was associated with a bony fragment (BHAGL). Conclusion: MR imaging was able to diagnose correctly this atypical injury complex which had not been suspected clinically or on the radiographs. (orig.)

2001-12-01

166

Osteoporosis posmenopausia según densitometría ósea / Postmenopausal osteoporosis according to bony densitometry  

Scientific Electronic Library Online (English)

Full Text Available SciELO Cuba | Language: Spanish Abstract in spanish Se realizó un estudio descriptivo y transversal de 146 mujeres, atendidas en la Consulta de Climaterio del Hospital General Docente "Dr. Juan Bruno Zayas Alfonso" de Santiago de Cuba, durante el 2010, con vistas a medir la pérdida de masa ósea en ellas. Los resultados mostraron como factores de ries [...] go predominantes: la ooforectomía bilateral antes de los 50 años, el cese de la menstruación antes de los 40 años y el bajo peso. La densitometría reveló que 45,9 % de las féminas padecía osteopenia y 35,6 %, osteoporosis, con alta significación de la relación entre el climaterio y los resultados densitométricos. Se concluyó que la osteoporosis es frecuente en esta etapa, por lo que debe ser diagnosticada precozmente, de modo que se asegure una terapia eficaz y mejore la calidad de vida. Abstract in english A descriptive and cross-sectional study in 146 women, assisted at the Climacteric Department in "Dr. Juan Bruno Zayas Alfonso" Teaching General Hospital from Santiago de Cuba was carried out during the 2010, with the objective of measuring the loss of bony mass in them. The results showed as predomi [...] nant risk factors: the bilateral oophorectomy before 50 years, the ceasing of menstruation before 40 years and low weight. The densitometry revealed that 45,9 % of the females suffered from osteopenia and 35,6 %, osteoporosis, with high significance of the relation between the climacteric and the densitometric results. It was concluded that osteoporosis is frequent in this stage, so that it should be early diagnosed, and an effective therapy be assured to improve life quality.

Couto Núñez, Dayana; Nápoles Méndez, Danilo; Deulofeu Betancourt, Isabel.

167

Periodontal bone lesions  

International Nuclear Information System (INIS)

In the course of life the periodontum is subject to changes which may be physiological or pathological. Intraoral radiographs give insight into the hard structures of the dentomaxillar region and provides information on lesions in the bone of the periodontum in that they show radiopacities and radiolucencies caused by such lesions. In this thesis the relation is investigated between the true shape and dimensions of periodontal bone lesions and their radiographic images. A method is developed and tested of making standardized and reproducible radiographs suitable for longitudinal studies of periodontal lesions. Also the possibility is demonstrated of an objective and reproducible interpretation of radiographic characteristics of periodontal bone lesions. (Auth.)

1985-01-01

168

Ocena morfologiczna g?ównych parametrów przewlek?ego zapalenia b?ony ?luzowej ?o??dka z zastosowaniem Systemu Sydney  

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Wprowadzenie: Endoskopia jest jedn? z wa?niejszych metod oceniaj?cych górny odcinek przewodu pokarmowego. Umo?liwia bezpo?redni? wizualizacj? oraz wykonanie celowanej biopsji. Wszechstronny opis parametrów histologicznych stanowi o warto?ci tego badania. Cel pracy: Ocena histopatologiczna b?ony ?luzowej ?o??dka z zastosowaniem uaktualnionego Systemu Sydney w grupie 308 pacjentów z klinicznym rozpoznaniem przewlek?ego zapalenia b?ony ?luzowej ?o??dka (PZ?). Podj?to pró...

2001-01-01

169

Laboratory effect of Boni Protect containing Aureobasidium pullulans (de Bary) Arnoud in the control of some fungal diseases of apple fruit  

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The efficacy of Aureobasidium pullulans (in the biopreparation Boni Protect) against different pathogens of apples (Botrytis cinerea, Monilinia fructigena, Penicillium expansum, and Pezicula malicorticis) was evaluated under laboratory con- ditions. The biocontrol product was applied at concentrations of 0.05%, 0.1%, and 0.5%. Fruits of apple cultivars 'Jonagold Decosta' and 'Pinova' were used. Boni Protect was very effective against B. cinerea on cv. 'Jona...

2013-01-01

170

Detection of hypoplasia of bony cochlear nerve canal by virtual endoscopy: a pilot study  

International Nuclear Information System (INIS)

Background: Dimensions of the bony cochlear nerve canal (BCNC) have been proposed as a potential diagnostic standard for hypoplasia of BCNC, but the standard remains inconsistent. We have previously found that a helix-like shape appears in normal BCNCs at VE images, whereas, the sign does not appear in some hypoplastic BCNCs. Purpose: To retrospectively examine the feasibility of computed tomographic (CT) virtual endoscopy (VE) in the evaluation of hypoplasia of BCNC on the basis of absence of a helix-like shape. Material and Methods: Twenty ears in 14 consecutive patients (mean age 5.5 years, range 1-15 years, 6 boys, 8 girls) diagnosed with hypoplasia of BCNC were included in this work. One hundred ears in 50 gender- and age-matched individuals (mean age 6.6 years, range 1-15 years, 29 boys, 21 girls) without inner ear disease and internal auditory canal (IAC) malformations served as controls. The presence or absence of a helix-like shape was evaluated by two independent reviewers. The value of VE for the diagnosis of hypoplasia of BCNC was assessed with clinical results and routine radiologic evaluation as the reference standard. Inter-observer agreement was calculated. Sensitivity, specificity, and accuracy were selected to test the diagnostic ability of the VE. Results: Absence of a helix-like shape was found in the cochlear area of 17 of 20 ears in patients with hypoplasia of BCNC but in none of the control subjects. Inter-observer agreement was substantial (? = 0.773). The diagnostic rates of absence of a helix-like shape for hypoplasia of BCNC in terms of sensitivity, specificity, and accuracy were 85%, 100%, and 98%, respectively. There were significant differences between the two groups with respect to VE findings for absence of a helix-like shape (P < 0.001). Conclusion: The absence of a helix-like shape at VE images may be used as a potentially useful sign in the diagnosis of hypoplasia of BCNC

2011-09-01

171

Detection of hypoplasia of bony cochlear nerve canal by virtual endoscopy: a pilot study  

Energy Technology Data Exchange (ETDEWEB)

Background: Dimensions of the bony cochlear nerve canal (BCNC) have been proposed as a potential diagnostic standard for hypoplasia of BCNC, but the standard remains inconsistent. We have previously found that a helix-like shape appears in normal BCNCs at VE images, whereas, the sign does not appear in some hypoplastic BCNCs. Purpose: To retrospectively examine the feasibility of computed tomographic (CT) virtual endoscopy (VE) in the evaluation of hypoplasia of BCNC on the basis of absence of a helix-like shape. Material and Methods: Twenty ears in 14 consecutive patients (mean age 5.5 years, range 1-15 years, 6 boys, 8 girls) diagnosed with hypoplasia of BCNC were included in this work. One hundred ears in 50 gender- and age-matched individuals (mean age 6.6 years, range 1-15 years, 29 boys, 21 girls) without inner ear disease and internal auditory canal (IAC) malformations served as controls. The presence or absence of a helix-like shape was evaluated by two independent reviewers. The value of VE for the diagnosis of hypoplasia of BCNC was assessed with clinical results and routine radiologic evaluation as the reference standard. Inter-observer agreement was calculated. Sensitivity, specificity, and accuracy were selected to test the diagnostic ability of the VE. Results: Absence of a helix-like shape was found in the cochlear area of 17 of 20 ears in patients with hypoplasia of BCNC but in none of the control subjects. Inter-observer agreement was substantial (? = 0.773). The diagnostic rates of absence of a helix-like shape for hypoplasia of BCNC in terms of sensitivity, specificity, and accuracy were 85%, 100%, and 98%, respectively. There were significant differences between the two groups with respect to VE findings for absence of a helix-like shape (P < 0.001). Conclusion: The absence of a helix-like shape at VE images may be used as a potentially useful sign in the diagnosis of hypoplasia of BCNC

Quan Yong; Wu Lebin; Gong Wuxian; Gong Ruozhen (Shandong Medical Imaging Research Institute, Shandong Univeristy, Jinan, Shandong (China)), email: grzh99@yahoo.com.cn; Zu Zushan (Dept. of Radiology, Wendeng Central Hospital, Weifang Medical College, Weihai (China))

2011-09-15

172

18F-FDG PET demonstrates previously unvisualised bony metastases in a lung cancer patient  

International Nuclear Information System (INIS)

Full text: A 59-year-old male, presented to his local doctor with the trivial complaint of a persistent dry cough. On clinical examination he was found to have an enlarged right supraclavicular lymph node. He was investigated with chest X-ray, Computerised Tomography (CT) and Fine Needle Aspiration Cytology (FNAC) of the palpable node CT showed a right lung mass, bulky hilar, mediastinal, supraclavicular and cervical lymph nodes FNAC was inconclusive due to an insufficient tissue sample, but suggestive of non-Hodgkin's Lymphoma. Hence excisional node biopsy was required which revealed non-small cell lung cancer (NSCLC). Subsequent CT scans of the abdomen and pelvis for staging revealed no distant involvement. Therefore radical radiotherapy was planned to treat the locally advanced disease. Prior to treatment a Positron Emission Tomography (PET) scan was organised by his specialist as a baseline study to monitor therapy progress. Non-Attenuation corrected images of the chest, abdomen and pelvis were obtained 40 minutes post administration of 394 MBq 18F-FDG, on a Siemens 951/3IR PET scanner. The images were reconstructed using both Filtered Back Projection (FBP) and Ordered Subsets-Expectation Maximization (OSEM) algorithms. The images revealed extensive metastases particularly in the spine and pelvis, besides the known locally advanced thoracic disease A 99mTc MDP bone scan and plain film radiographs aimed at confirming bony metastases were negative, even though the bone scan noted a slight focus in the right fourth rib. The appearance suggested trauma, but a solitary bone metastasis could not be ruled out MRI of the spine confirmed the PET scan findings. Mr RD was to have curative radical radiotherapy, but after the PET results, it was decided to treat him palliatively. The value of 18F-FDG PET in staging some cancers such as NSCLC is widely accepted, in this case it was pivotal in altering the patient's management. Copyright (2002) The Australian and New Zealand Society of Nuclear Medicine Inc

2002-05-04

173

Save-a-tooth: Conservative surgical management of dentigerous cyst  

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Dentigerous cysts are the most common bony lesions of the jaws in children. It is one of the most prevalent types of odontogenic cysts associated with an erupted or developing tooth, particularly the mandibular third molars; the other teeth that are commonly affected are, in order of frequency, the maxillary canines, the maxillary third molars, and rarely the central incisors. Radiographically, the cyst appears as ovoid well-demarcated unilocular radiolucency with a sclerotic border. Careful ...

Shivaprakash P; Rizwanulla T; Baweja D; Noorani H

2009-01-01

174

Dentigerous cysts of anterior maxilla in a young child: A case report  

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Dentigerous cysts are the most common bony lesions of the jaws in children. It is one of the most prevalent types of odontogenic cysts associated with an erupted or developing tooth, particularly the mandibular third molars; the other teeth that are commonly affected are, in order of frequency, the maxillary canines, the maxillary third molars and, rarely, the central incisor. Radiographically, the cyst appears as ovoid well-demarcated unilocular radiolucency with a sclerotic border. The pres...

Kalaskar R; Tiku A; Damle S

2007-01-01

175

Assessing the anatomical variations of lingual foramen and its bony canals with CBCT taken from 102 patients in Isfahan  

Science.gov (United States)

Background: Some studies have been performed on assessing the anatomical variations of lingual foramen and its bony canals, in many different countries but no study has been performed in Iran yet. The purpose of this study is to assess the anatomical variations of lingual foramen and its bony canals with cone-beam computed tomography (CBCT) imaging in Isfahan. Materials and Methods: This was a cross-sectional study in which CBCT images taken from 102 patients referred to the Radiology Department of Head and Neck in Esfahan (Iran) University between 2010 and 2011. The presence of the lingual foramen and its bony canals, the locations, sizes, and length were assessed. The distances between the terminal end of lingual canal at the buccal and lingual side from the inferior border of the mandible and alveolar crest were measured. We also evaluated the effect of patient age and gender on the dimensional measurements of the anatomical landmark mentioned above t test, analysis of variance (ANOVA), and pearson's correlation were used for statistical analysis and P value lower than 0.05 was considered significant. Result: All of the CBCT images taken showed the presence of lingual foramen. Of all the participants, 52% of them had two foramens in their images. The mean diameters of the upper and lower lingual foramen were 1.12 and 0.9 mm, respectively. Conclusion: These anatomical landmarks in Isfahan population vary from previous studies. All of the images had at least one lingual foramen which demonstrates high prevalence of this anatomy among Isfehanian population. Therefore, it is recommended to use CBCT imaging for preoperative evaluation prior to installing dental implants.

Sheikhi, Mahnaz; Mosavat, Farzaneh; Ahmadi, Ahura

2012-01-01

176

MRI of degenerative bone marrow lesions in experimental osteoarthritis of canine knee joints  

International Nuclear Information System (INIS)

Objective. The objective of this study was to determine the value of MRI in the detection of degenerative bone marrow abnormalities in an animal osteoarthritis model. Design. In 10 dogs with experimentally induced unilateral osteoarthritis of the knee, MRI was performed using two-dimensional spin-echo (2D-SE) and three-dimensional gradient-echo (3D-GE) imaging. Contrast enhanced T1-weighted 2D-SE sequences were also obtained after injection of gadolinium-DTPA. The results were compared with the gross and histopathologic findings and with radiography. Results. Histopathologic specimens revealed 21 osteosclerotic lesions and 5 intraosseous cysts. On 2D-SE images, 24 of 26 lesions were detected, while 21 of 26 lesions were identified on 2D-GE sequences. Radiography, including conventional tomography, demonstrated 9 of 26 lesions. Regardless of the sequence weighting, all osteosclerotic lesions appeared hypointense on MRI. Signal loss in bone sclerosis resulted primarily from the reduction of intact fat marrow, the increased bone density being of secondary importance. Quantitative signal analysis allowed approximate estimation of the grade of sclerosis. On postcontrast images, sclerotic bone remained hypointense, although significant but non-specific enhancement relative to the normal fat marrow was observed. The extent of contrast enhancement did not correlate with the grade of osteosclerosis. All five cysts were readily diagnosed by MRI. Cysts displayed either central or marginal contrast enhancement within their cavities. Conclusions. MRI provides a sensitive method for the diagnosis of osteoarthritic bone abnormalities, allowing their differentiation from most non-degenerative subarticular lesions. (orig.). With 1 tab

1996-07-01

177

Distance-to-Agreement Investigation of Tomotherapy's Bony Anatomy-Based Autoregistration and Planning Target Volume Contour-Based Optimization  

International Nuclear Information System (INIS)

Purpose: To compare Tomotherapy's megavoltage computed tomography bony anatomy autoregistration with the best achievable registration, assuming no deformation and perfect knowledge of planning target volume (PTV) location. Methods and Materials: Distance-to-agreement (DTA) of the PTV was determined by applying a rigid-body shift to the PTV region of interest of the prostate from its reference position, assuming no deformations. Planning target volume region of interest of the prostate was extracted from the patient archives. The reference position was set by the 6 degrees of freedom (dof)—x, y, z, roll, pitch, and yaw—optimization results from the previous study at this institution. The DTA and the compensating parameters were calculated by the shift of the PTV from the reference 6-dof to the 4-dof—x, y, z, and roll—optimization. In this study, the effectiveness of Tomotherapy's 4-dof bony anatomy–based autoregistration was compared with the idealized 4-dof PTV contour-based optimization. Results: The maximum DTA (maxDTA) of the bony anatomy-based autoregistration was 3.2 ± 1.9 mm, with the maximum value of 8.0 mm. The maxDTA of the contour-based optimization was 1.8 ± 1.3 mm, with the maximum value of 5.7 mm. Comparison of Pearson correlation of the compensating parameters between the 2 4-dof optimization algorithms shows that there is a small but statistically significant correlation in y and z (0.236 and 0.300, respectively), whereas there is very weak correlation in x and roll (0.062 and 0.025, respectively). Conclusions: We find that there is an average improvement of approximately 1 mm in terms of maxDTA on the PTV going from 4-dof bony anatomy-based autoregistration to the 4-dof contour-based optimization. Pearson correlation analysis of the 2 4-dof optimizations suggests that uncertainties due to deformation and inadequate resolution account for much of the compensating parameters, but pitch variation also makes a statistically significant contribution

2013-03-01

178

Osteopathology in the feet of rhinoceroses: lesion type and distribution.  

Science.gov (United States)

An estimated 1,170 white (Ceratotherium simum), black (Diceros bicornis), greater one-horned (Rhinoceros unicornis), and Sumatran (Dicerorhinus sumatrensis) rhinoceroses are kept in captivity worldwide, where they are a popular public attraction and serve important roles in education and conservation. Rhinoceroses in captivity are reportedly affected by a variety of foot conditions, including abscesses, nail cracking, and pododermatitis, but there are few studies reporting associated bony pathology in these species. This study aimed to describe osteopathology in rhinoceros feet and identify normal and abnormal osteologic features of rhinoceros feet. The metacarpal-tarsal and phalangeal bones from 81 feet (67 skeletal specimens and 14 cadaveric feet), derived from 27 rhinoceroses of various species, were evaluated in the study (1 black, 11 white, 2 greater one-horned, 3 Javan, 9 Sumatran, and 1 unknown). Bones were examined visually (skeletal specimens) or by computed tomography (cadaver specimens) for evidence of bony lesions. Of the 27 rhinoceroses examined, 22 showed some degree of bone pathology in at least one limb. Six broad categories of pathologic change were identified, with numbers in parentheses representing numbers of rhinoceroses with lesions in at least one limb/number of rhinoceroses examined: enthesopathy (20/27), osteoarthritis (15/27), pathologic bone remodeling (12/27), osteitis-osteomyelitis (3/27), fracture (3/8), and subluxation (3/8). The frequency of pathologic changes in fore- and hind limbs was not significantly different. Most (91%) enthesopathies were observed on the proximal phalanges of the digits, and osteoarthritis was most common in the distal interphalangeal joints of the medial and lateral digits (32 and 26%, respectively). In addition to the pathology described, all examined rhinoceroses also had multiple small surface lucencies in the distal limb bones as an apparently normal anatomic feature. This study is an important first step in identifying both normal and pathologic features of rhinoceros feet and hopefully will thereby contribute to the improved knowledge and care of these species. PMID:24450050

Regnault, Sophie; Hermes, Robert; Hildebrandt, Thomas; Hutchinson, John; Weller, Renate

2013-12-01

179

Bony outgrowths on the jaws of an extinct sperm whale support macroraptorial feeding in several stem physeteroids  

Science.gov (United States)

Several extinct sperm whales (stem Physeteroidea) were recently proposed to differ markedly in their feeding ecology from the suction-feeding modern sperm whales Kogia and Physeter. Based on cranial, mandibular, and dental morphology, these Miocene forms were tentatively identified as macroraptorial feeders, able to consume proportionally large prey using their massive teeth and robust jaws. However, until now, no corroborating evidence for the use of teeth during predation was available. We report on a new specimen of the stem physeteroid Acrophyseter, from the late middle to early late Miocene of Peru, displaying unusual bony outgrowths along some of the upper alveoli. Considering their position and outer shape, these are identified as buccal maxillary exostoses. More developed along posterior teeth and in tight contact with the high portion of the dental root outside the bony alveoli, the exostoses are hypothesized to have developed during powerful bites; they may have worked as buttresses, strengthening the teeth when facing intense occlusal forces. These buccal exostoses further support a raptorial feeding technique for Acrophyseter and, indirectly, for other extinct sperm whales with a similar oral apparatus ( Brygmophyseter, Livyatan, Zygophyseter). With a wide size range, these Miocene stem physeteroids were major marine macropredators, occupying ecological niches nowadays mostly taken by killer whales.

Lambert, Olivier; Bianucci, Giovanni; Beatty, Brian L.

2014-06-01

180

Bony outgrowths on the jaws of an extinct sperm whale support macroraptorial feeding in several stem physeteroids  

Science.gov (United States)

Several extinct sperm whales (stem Physeteroidea) were recently proposed to differ markedly in their feeding ecology from the suction-feeding modern sperm whales Kogia and Physeter. Based on cranial, mandibular, and dental morphology, these Miocene forms were tentatively identified as macroraptorial feeders, able to consume proportionally large prey using their massive teeth and robust jaws. However, until now, no corroborating evidence for the use of teeth during predation was available. We report on a new specimen of the stem physeteroid Acrophyseter, from the late middle to early late Miocene of Peru, displaying unusual bony outgrowths along some of the upper alveoli. Considering their position and outer shape, these are identified as buccal maxillary exostoses. More developed along posterior teeth and in tight contact with the high portion of the dental root outside the bony alveoli, the exostoses are hypothesized to have developed during powerful bites; they may have worked as buttresses, strengthening the teeth when facing intense occlusal forces. These buccal exostoses further support a raptorial feeding technique for Acrophyseter and, indirectly, for other extinct sperm whales with a similar oral apparatus (Brygmophyseter, Livyatan, Zygophyseter). With a wide size range, these Miocene stem physeteroids were major marine macropredators, occupying ecological niches nowadays mostly taken by killer whales.

Lambert, Olivier; Bianucci, Giovanni; Beatty, Brian L.

2014-05-01

 
 
 
 
181

Ultrasonographic findings of soft tissue lesions in extremities  

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52 patients who had soft tissue lesions in extremity, buttock and shoulder,were studied by ultrasonography to evaluated the finding and significance of ultrasound study. The results were follows; 1. There were variable entities of diseases including 16 cases of Baker's cysts, 8 cases of abscesses, 8 cases of neoplasms, 4 case of hematomas and each case of joint effusion and bursitis, ganglion, thickening of soft tissue, muscle rupture and foreign body, respectively. 2. Baker's cyst was possibly diagnosis by characteristic site and finding with clinical history. 3. Abscess and hematoma showed hypoechoic or anechoic mass. Hematoma was easily diagnosed by associated findings with trauma, such as muscular swelling and rupture or bony fracture, but it was difficult to distinguish abscess from neoplasm due to similar finding. 4. Ultrasonography was a modality not only accurate for determining the presence, size and localization of lesion, but also easy for defining cyst or solid nature and relationship between lesion and adjacent structure.

Yang, Hae Ran; Lee, Dong Ho; Ko, Young Tae; Lee, Sun Wha; Lim, Jae Hoon [Kyung Hee University Hospital, Seoul (Korea, Republic of)

1989-02-15

182

Intraosseous osteolytic lesions  

International Nuclear Information System (INIS)

Any pathological damage occurring in a bone will produce either an osteolytic or osteosclerotic lesion which can be seen in the macroscopic specimen as well as in the roentgenogram. Various bone lesions may lead to local destructions of the bone. An osteoma or osteoplastic osteosarcoma produces an osteosclerotic lesion showing a dense mass in the roentgenogram; a chondroblastoma or an osteoclastoma, on the other hand, induces an osteolytic focal lesion. This paper presents examples of different osteolytic lesions of the humerus. An osteolytic lesion seen in the roentgenogram may be either produced by an underlying non-ossifying fibroma of the bone, by fibrous dysplasia, osteomyelitis or Ewing's sarcoma. Differential diagnostic considerations based on the radiological picture include eosinophilic bone granuloma, juvenile or aneurysmal bone cyst, multiple myeloma or bone metastases. Serious differential diagnostic problems may be involved in case of osteolytic lesions occurring in the humerus. Cases of this type involving complications have been reported and include the presence of an teleangiectatic osteosarcoma as well as that of a hemangiosarcoma of the bone. (orig.)

1981-01-01

183

Influence of rotational setup error on tumor shift in bony anatomy matching measured with pulmonary point registration in stereotactic body radiotherapy for early lung cancer  

International Nuclear Information System (INIS)

The objective of this study was to examine the correlation between the patient rotational error measured with pulmonary point registration and tumor shift after bony anatomy matching in stereotactic body radiotherapy for lung cancer. Twenty-six patients with lung cancer who underwent stereotactic body radiotherapy were the subjects. On 104 cone-beam computed tomography measurements performed prior to radiation delivery, rotational setup errors were measured with point registration using pulmonary structures. Translational registration using bony anatomy matching was done and the three-dimensional vector of tumor displacement was measured retrospectively. Correlation among the three-dimensional vector and rotational error and vertebra-tumor distance was investigated quantitatively. The median and maximum rotational errors of the roll, pitch and yaw were 0.8, 0.9 and 0.5, and 6.0, 4.5 and 2.5, respectively. Bony anatomy matching resulted in a 0.2-1.6 cm three-dimensional vector of tumor shift. The shift became larger as the vertebra-tumor distance increased. Multiple regression analysis for the three-dimensional vector indicated that in the case of bony anatomy matching, tumor shifts of 5 and 10 mm were expected for vertebra-tumor distances of 4.46 and 14.1 cm, respectively. Using pulmonary point registration, it was found that the rotational setup error influences the tumor shift. Bony anatomy matching is not appropriate for hypofractionated stereotactic body radiotherapy with a tight margin. (author)

2012-12-01

184

[Cystic sacrococcygeal lesions].  

Science.gov (United States)

Eleven out of twelve cases of sacrococcygeal cystic lesions, 10 females and 2 males, with ages ranging from 12 to 64 underwent surgical excision with the pathological diagnosis of teratoma in 1, dermoid in 4 and epidermal cyst in 6. Most lesions were multicystic and located in the perirecto-coccygeal region, some are extending into the pelvic cavity. Occult lesions may bulge toward the rectal lumen and thus could be early detected by digital examination or proctoscopy. Early surgery is advocated for fear of malignant change and secondary infection and coccygectomy advised to ensure satisfactory exposure. PMID:2776548

Yang, K C

1989-02-01

185

Combined radiation lesions  

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Problems of combined radiation lesions resulting from intakes of nuclear fission products into the organism are discussed. It is shown that external and internal radiation dose rates determine the gravity of radiation sickness and its specific clinical course after combined radiation lesions, external radiation affecting the organism shortly after the exposure and internal radiation producing a considerable effect in remote time after the radiation effect. It is noted that combined radiation lesions increase the intensity of biochemical disorders, one of the reasons being the radiation injury of liver and thyroid. It is emphasized that internal radiation creates preconditions for decreasing organism stability to exogenous and endogenous infections.

Vasilenko, I.Ya.

1982-01-01

186

Diffuse cavitary lung lesions  

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An 11-year-old girl presented with a 2-month history of progressively worsening cough, daily fevers, and weight loss. A chest radiograph revealed multiple cystic cavitary lung lesions. An extensive infectious work-up was negative. Chest CT verified multiple cavitary lung lesions bilaterally, and [F-18]2-fluoro-2-deoxy-D-glucose ({sup 18}F-FDG) positron emission tomography with CT (PET/CT) showed increased uptake in the lung lesions as well as regional lymph nodes. Subsequent biopsy of an involved lymph node confirmed classical Hodgkin lymphoma, nodular sclerosis type. This case represents an unusual presentation for a child with Hodgkin lymphoma and demonstrates a role for {sup 18}F-FDG PET/CT in evaluating a child with cavitary lung lesions. (orig.)

Grunzke, Mindy; Garrington, Timothy [University of Colorado Denver, Department of Pediatrics, Aurora, CO (United States); The Children' s Hospital, Rick Wilson Center for Cancer and Blood Disorders, Aurora, CO (United States); Hayes, Kari [The Children' s Hospital, Pediatric Radiology, Aurora, CO (United States); Bourland, Wendy [Children' s Hospital at St. Francis, Warren Clinic, Inc., Tulsa, OK (United States)

2010-02-15

187

Tooth Abfraction Lesions  

Science.gov (United States)

Tooth Abfraction Lesions What Is It? Symptoms Diagnosis Expected Duration Prevention Treatment When To Call a Professional ... affect the enamel , the outer layer of the tooth. In severe cases, the dentin and cementum layers ...

188

The indeterminate adrenal lesion.  

Science.gov (United States)

With the increasing use of abdominal cross-sectional imaging, incidental adrenal masses are being detected more often. The important clinical question is whether these lesions are benign adenomas or malignant primary or secondary masses. Benign adrenal masses such as lipid-rich adenomas, myelolipomas, adrenal cysts and adrenal haemorrhage have pathognomonic cross-sectional imaging appearances. However, there remains a significant overlap between imaging features of some lipid-poor adenomas and malignant lesions. The nature of incidentally detected adrenal masses can be determined with a high degree of accuracy using computed tomography (CT) and magnetic resonance imaging (MRI) alone. Positron emission tomography (PET) is also increasingly used in clinical practice in characterizing incidentally detected lesions. We review the performance of the established and new techniques in CT, MRI and PET that can be used to distinguish benign adenomas and malignant lesions of the adrenal gland. PMID:20299300

Sahdev, Anju; Willatt, Jon; Francis, Isaac R; Reznek, Rodney H

2010-01-01

189

Acute nontraumatic liver lesions.  

Science.gov (United States)

The principal conditions requiring emergency/urgent intervention in patients with nontraumatic liver lesions are hemorrhage (with or without tumor rupture), rupture of hydatid cysts (with or without infection), complications arising from liver abscesses or congenital liver cysts, rupture related to peliosis hepatis, and in rare cases spontaneous hemorrhage. This article examines each of these conditions, its appearance on ultrasound (the first-line imaging method of choice for assessing any urgent nontraumatic liver lesion) and indications for additional imaging studies. PMID:24432172

Caremani, Marcello; Tacconi, Danilo; Lapini, Laura

2013-11-26

190

Male breast lesions  

International Nuclear Information System (INIS)

Roentgenographic examination of the male breast is an important aspect of the continued, intensive investigation of the radiologic morphology of the normal and diseased breast conducted in 17 cases examined at the Instituto Nacional do Cancer - RJ. It is purpose of this report to present the Roentgen appearance of various lesions of the male breast as they have been found in our practice and also to stress some of the difficulties in the differential diagnosis of these lesions. (author)

1989-01-01

191

Andersson Lesion in Ankylosing Spondylitis  

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Full Text Available Andersson lesions are destructive foci that appear at the discovertebral junction in ankylosingspondylitis. We report three cases of ankylosing spondylitis with such lesions. These lesions simulatean infection and in our country, mimic spinal tuberculosis.

Manimegalai N, KrishnanKutty K, Panchapakesa Rajendran C, Rukmangatharajan S, Rajeswari S

2004-04-01

192

Bony variations on coronary CT cuts of the paranasal sinuses. Knoecherne Variationen im koronaren Nasennebenhoehlen-CT  

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Bony variations in the anterior ethmoids may, if severe, play an important role in the development of chronic sinusitis and present the surgeon with added risks during operation. We have, therefore, analysed 390 preoperative CT examinations of the sinuses performed in the coronary plane with respect to the frequency of bone variations. Concha bullosa, increased pneumatisation of the agger nasi, large ethmoidal bullae, Haller's cells and increased pneumatisation of the sphenoid were found with equal frequency in about 20%. The most common variants occurred in the uncinate process (31.5%), less common were paradoxical curve of the middle turbinates (13.3%) and very rare were Onodi cells (1.3%). (orig.)

Koesling, S. (Abt. Diagnostische Radiologie, Klinik fuer Radiologie, Univ. Leipzig (Germany)); Wagner, F. (Abt. Diagnostische Radiologie, Klinik fuer Radiologie, Univ. Leipzig (Germany)); Schulz, H.G. (Abt. Diagnostische Radiologie, Klinik fuer Radiologie, Univ. Leipzig (Germany)); Heywang-Koebrunner, S. (Abt. Diagnostische Radiologie, Klinik fuer Radiologie, Univ. Leipzig (Germany))

1993-12-01

193

The platelet storage lesion.  

Science.gov (United States)

The gradual loss of quality in stored platelets as measured collectively with various metabolic, functional, and morphologic in vitro assays is known as the platelet storage lesion. With the advent of pathogen reduction technologies and improved testing that can greatly reduce the risk for bacterial contamination, the platelet storage lesion is emerging as the main challenge to increasing the shelf life of platelet concentrates. This article discusses the contribution of platelet production methods to the storage lesion, long-established and newly developed methods used to determine platelet quality, and the significance for clinical transfusion outcome. Highlighted are the novel technologies applied to platelet storage including platelet additive solutions and pathogen inactivation. PMID:20513565

Devine, Dana V; Serrano, Katherine

2010-06-01

194

Management of an endo perio lesion in a maxillary canine using platelet-rich plasma concentrate and an alloplastic bone substitute  

Directory of Open Access Journals (Sweden)

Full Text Available To evaluate the efficacy of platelet-rich plasma concentrate in the management of a cirumferential, infrabony defect associated with an endoperio lesion in a maxillary canine. A 45 year-old male patient with an endoperio lesion in the left maxillary canine was initially treated with endodontic therapy. Following the endodontic treatment, the circumferential, infrabony defect was treated using platelet-rich plasma and an alloplastic bone substitute. At the end of three months, there was a gain in the clinical attachment level and reduction in probing depth. Radiographic evidence showed that there was significant bony fill. The results were maintained at the time of recall nine months later.

Singh Sangeeta

2009-01-01

195

Radiologic diagnosis of the shoulder dislocation and its associated osseous lesions  

International Nuclear Information System (INIS)

Among the dislocations of the larger joints of the human body, those of the shoulder are the most frequent ones. They are often associated with osseous lesions, which are of importance in treatment and prognosis. Radiologic diagnostic procedures must take this into consideration in view of the causal mechanisms of trauma. In search for the bony lesions, routine techniques of projection exist which are evidently not always used as often as would be desirable. These projections also help to detect and to accurately locate the dislocation, which may sometimes be difficult to diagnose. Posterior dislocations, for example, are misdiagnosed or overlooked radiologically (and clinically) in about 50% of the cases. This could partly be avoided by the consequent use of a few, but essential projection procedures. (orig.)

1983-07-01

196

Development of efficient electron beam irradiating condition of artificial bone substitutes with 7 to 3 ratio of hydroxyapatite, tricalcium phosphate and type I collagen to maximize bony regeneration  

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Bony defects in oral and maxillofacial region was a common problem -Auto graft -Allograft -Xenograft. Accenting bone is 'Gold standard' for bone defect repair and from the rib, iliac crest, jaw and tibia. Bone is 70% inorganic components -which provide firmness, and approx. and 30% organic substances.

Kim, Soung Min; Eo, Mi Young; Myoung, Hoon; Kang, Ji Young; Lee, Jong Ho [Seoul National Univ., Seoul (Korea, Republic of); Cho, Hye Jin [Korea Basic Science Institute, Daejeon (Korea, Republic of); Yea, Kwon Hae; Lee, Byungcheol [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

2011-07-01

197

Development of mandibular, hyoid and hypobranchial muscles in the zebrafish: homologies and evolution of these muscles within bony fishes and tetrapods  

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Abstract Background During vertebrate head evolution, muscle changes accompanied radical modification of the skeleton. Recent studies have suggested that muscles and their innervation evolve less rapidly than cartilage. The freshwater teleostean zebrafish (Danio rerio) is the most studied actinopterygian model organism, and is sometimes taken to represent osteichthyans as a whole, which include bony fishes and tetrapods. Most work concerning zebrafish cranial muscles...

Diogo Rui; Hinits Yaniv; Hughes Simon M

2008-01-01

198

Zaka?enie Helicobacter pylori - proces zapalny czy alergiczny? Ocena st??enia cytokin b?ony ?luzowej ?o??dka  

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Full Text Available Przyjmuje si?, ?e wybrane cytokiny odgrywaj? wa?n? rol? w patogenezie zapalenia b?ony ?luzowej przewodu pokarmowego w przebiegu zaka?enia Helicobacter pylori (H. pylori. Ich znaczenie w tym procesie chorobowym nie zosta?o jeszcze poznane. Za cel pracy przyj?to ocen? st??enia wybranych cytokin w b?onie ?luzowej ?o??dka u dzieci zaka?onych t? bakteri?. Uzyskane wyniki porównywano ze st??eniem tych samych cytokin w b?onie ?luzowej dzieci z alergi? pokarmow? oraz chorych z grupy odniesienia. Badania obejmowa?y 97 dzieci w wieku od 6 do 17 lat. U wszystkich chorych, ze wzgl?du na g?ówne objawy dys-peptyczne z przewodu pokarmowego, wykonano badanie endoskopowe górnego odcinka, oceniaj?c b?on? ?luzow? makroskopowo i histopatologicznie z uwzgl?dnieniem obecno?ci H. pylori. W pobranych z cz??ci przyod?wiernikowej skrawkach b?ony ?luzowej oznaczano st??enie nast?puj?cych cytokin: IL-2, IL-4, IFN-y, IL-5, IL-8, IL-10, TNF-a. Zastosowano metod? ELISA i standardowe zestawy firmy ENDOGEN (USA. Przeprowadzone badania wykaza?y wzrost lokalnej produkcji wszystkich badanych cytokin. Stwierdzono znamienne statystycznie ró?nice w st??eniach IFN-y, IL-2, IL-8 oraz TNF-a u dzieci zaka?onych H. pylori i u dzieci z alergi? pokarmow?.

El?bieta Maciorkowska

2000-12-01

199

Immunopathology of skin lesions  

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Full Text Available A study was conducted on 130 patients suffering from skin lesions which included psoriasis, lichen planus, DLE, pemphigus, vitiligo and alopecia areata. Forty age-and-sex-matched healthy individuals served as control. Serum IgG, IgM, and circulating immune complexes (CIC were estimated. Significant increase in serum IgG (1937.2 ± 1030.43 mg% and IgM (232.12 ± 136.98 mg% was observed in all the skin lesions when compared with controls except in lichen planus where they were significantly lowered, values being 580.61± 77.35 mg% and 66.88 ± 6.59mg% respectively. CIC levels were significantly raised (P<0.00 1 in various skin lesions (40.49±23.29 when compared with controls (17.68± 3.21, but no significance was observed in lichen planus( 17.72 ± 4.28. Serum IgG, IgM and CIC were statistically significantly altered depending on the extent of the lesion and lowered significantly to almost normal values following treatment, thereby confirming the role of immunity in the pathogenesis of these skin disorders.

Khan Nazoora

2001-09-01

200

Genital lesions following bestiality  

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Full Text Available A 48-year-old man presented with painful genital lesions with history of bestiality and abnor-mal sexual behaviour. Examination revealed multiple irregular tender ulcers and erosions, with phimosis and left sided tender inguinal adenopathy. VDRL, TPHA, HIV-ELISA were negative. He was treated with ciprofloxacin 500mg b.d. along with saline compresses with complete resolution.

Mittal A

2000-01-01

 
 
 
 
201

Post-traumatic glenohumeral cartilage lesions: a systematic review  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Any cartilage damage to the glenohumeral joint should be avoided, as these damages may result in osteoarthritis of the shoulder. To understand the pathomechanism leading to shoulder cartilage damage, we conducted a systematic review on the subject of articular cartilage lesions caused by traumas where non impression fracture of the subchondral bone is present. Methods PubMed (MEDLINE, ScienceDirect (EMBASE, BIOBASE, BIOSIS Previews and the COCHRANE database of systematic reviews were systematically scanned using a defined search strategy to identify relevant articles in this field of research. First selection was done based on abstracts according to specific criteria, where the methodological quality in selected full text articles was assessed by two reviewers. Agreement between raters was investigated using percentage agreement and Cohen's Kappa statistic. The traumatic events were divided into two categories: 1 acute trauma which refers to any single impact situation which directly damages the articular cartilage, and 2 chronic trauma which means cartilage lesions due to overuse or disuse of the shoulder joint. Results The agreement on data quality between the two reviewers was 93% with a Kappa value of 0.79 indicating an agreement considered to be 'substantial'. It was found that acute trauma on the shoulder causes humeral articular cartilage to disrupt from the underlying bone. The pathomechanism is said to be due to compression or shearing, which can be caused by a sudden subluxation or dislocation. However, such impact lesions are rarely reported. In the case of chronic trauma glenohumeral cartilage degeneration is a result of overuse and is associated to other shoulder joint pathologies. In these latter cases it is the rotator cuff which is injured first. This can result in instability and consequent impingement which may progress to glenohumeral cartilage damage. Conclusion The great majority of glenohumeral cartilage lesions without any bony lesions are the results of overuse. Glenohumeral cartilage lesions with an intact subchondral bone and caused by an acute trauma are either rare or overlooked. And at increased risk for such cartilage lesions are active sportsmen with high shoulder demand or athletes prone to shoulder injury.

Stussi Edgar

2008-07-01

202

Radiological diagnosis of chronic spinal cord compressive lesion at thoraco-lumbar junction  

Energy Technology Data Exchange (ETDEWEB)

Radiological findings in five cases with chronic spinal cord compressive lesion at thoraco-lumbar junction were reported. Three cases had spondylosis and two cases had ossification of yellow ligament (OYL). The levels of the lesions were T12/L1 in three cases and T11/12 in two cases. Two out of three spondylotic patients had also OYL at the same level. The five cases consisted of three men and two women. The ages ranged from 42 to 60 years old with a mean age of 53 years old. Neurologically, every patient showed flaccid paresis and sensory disturbance of the legs. Two cases had sensory disturbance of stocking type. The intervals from the onset of the symptoms to the final diagnosis were 6 months, 7 years, 8 years, 11 years and 12 years. Myelography showed anterior spinal cord compression by bony spur in spondylotic patients, and posterior compression by OYL in other cases. Myelography in flexion posture disclosed the cord compression by bony spur more clearly in two out of three spondylotic patients. Delayed CT-myelography showed intramedullary filling of contrast material in two cases, which indicated degenerative change or microcavitation due to long term compression of the spinal cord. MRI was taken in three spondylotic patients and could directly show compression of the spinal cord. Difficulty in detecting abnormality at thoraco-lumbar junction on plain roentgenogram, and similarity of the symptoms to peripheral nerve disease often lead to a delay in diagnosis. The significance of dynamic myelography and delayed CT-myelography when dealing with such a lesion was discussed here. MRI is also a useful method for diagnosing a compressive lesion at the thoraco-lumbar junction.

Koyanagi, Izumi; Isu, Toyohiko; Iwasaki, Yoshinobu; Akino, Minoru; Abe, Hiroshi; Tashiro, Kunio; Miyasaka, Kazuo; Abe, Satoru; Kaneda, Kiyoshi

1988-10-01

203

Radiological diagnosis of chronic spinal cord compressive lesion at thoraco-lumbar junction  

International Nuclear Information System (INIS)

Radiological findings in five cases with chronic spinal cord compressive lesion at thoraco-lumbar junction were reported. Three cases had spondylosis and two cases had ossification of yellow ligament (OYL). The levels of the lesions were T12/L1 in three cases and T11/12 in two cases. Two out of three spondylotic patients had also OYL at the same level. The five cases consisted of three men and two women. The ages ranged from 42 to 60 years old with a mean age of 53 years old. Neurologically, every patient showed flaccid paresis and sensory disturbance of the legs. Two cases had sensory disturbance of stocking type. The intervals from the onset of the symptoms to the final diagnosis were 6 months, 7 years, 8 years, 11 years and 12 years. Myelography showed anterior spinal cord compression by bony spur in spondylotic patients, and posterior compression by OYL in other cases. Myelography in flexion posture disclosed the cord compression by bony spur more clearly in two out of three spondylotic patients. Delayed CT-myelography showed intramedullary filling of contrast material in two cases, which indicated degenerative change or microcavitation due to long term compression of the spinal cord. MRI was taken in three spondylotic patients and could directly show compression of the spinal cord. Difficulty in detecting abnormality at thoraco-lumbar junction on plain roentgenogram, and similarity of the symptoms to peripheral nerve disease often lead to a delay in diagnosis. The significance of dynamic myelography and delayed CT-myelography when dealing with such a lesion was discussed here. MRI is also a useful method for diagnosing a compressive lesion at the thoraco-lumbar junction. (author)

1988-01-01

204

Filling a cervical spine cage with local autograft: change of bone density and assessment of bony fusion.  

Science.gov (United States)

To date, it remains debatable whether cervical spine fusion cages should be filled with any kind of bone or bone substitute. Using a bone substitute would produce additional costs, using an autologous bone graft from the iliac crest would make the use of the cage at least questionable. As an alternative, cortical and subcortical bone from the anterior osteophytes of the segment in which the disc has been removed could be used to fill the cage: higher costs and complications at the iliac crest could both be avoided and the cage could be filled. However, the fate of these bone chips made from the anterior osteophytes is unclear as well as whether fusion will occur using this technique. The objective of the current study was to investigate possible changes in the bone density of this local autograft in the cage within the first 12 months after surgery by means of computed tomography. A second objective was to assess segmental bony fusion using this technique. 21 patients, suffering from degenerative disc disease of the cervical spine, were included into this prospective study. They all underwent anterior decompression, cage insertion and plate stabilisation. The cage (Rabea, Signus Medizintechnik, Alzenau, Germany), was filled with bone chips made from the anterior osteophytes of the segment that underwent discectomy. On the third day after surgery as well as three, six and 12 months after surgery, an axial computed tomography scan through the cage was taken and density within the apertures of the cage was measured in a standardised manner. Flexion-extension lateral radiographs were taken to investigate segmental fusion. Statistical significance was assumed to be at a 95 % level of significance. 23 cages were implanted. The mean value of the bone density obtained by computed tomography was 505 (+/- 119) HU on day three, 635 (+/- 156) HU after three months, 769 (+/- 162) HU after six months, and 814 (+/- 198) after 12 months. There was a significant difference when the values after 12 months were compared to those obtained after three days (p < 0.001) and after three months (p = 0.004). Bony fusion was seen in 21 out of 23 segments (91.3 %) after 12 months. It may be concluded that this technique could be an alternative to the current treatment options. PMID:16518745

Pitzen, T; Kiefer, R; München, D; Barbier, D; Reith, W; Steudel, W I

2006-02-01

205

Percutaneous bone lesion ablation.  

Science.gov (United States)

Benign tumors and metastatic bone lesions can be treated by ablation techniques performed either alone or in combination with other percutaneous techniques. Ablation techniques include ethanol or acetic acid injection and thermal ablation by means of energy deposition [including laser, radiofrequency, microwave, cryoablation, radiofrequency ionization and magnetic resonance (MR)-guided high-intensity focused ultrasound (HIFU)]. Goal definition of the therapy is crucial: ablation techniques can be proposed as curative treatments in benign bone tumors or oligometastatic disease (high success and relatively low rates of potential complications, mainly iatrogenic thermal damage of surrounding sensitive structures. Successful thermal ablation requires a sufficient ablation volume and thermal protection of the surrounding vulnerable structures. This article will describe the general principles governing ablation and the mechanism of action for each technique and in addition will review the literature about safety and effectiveness of percutaneous imaging-guided ablation for benign and malignant (primary and metastatic) lesions. PMID:24894924

Filippiadis, Dimitrios K; Tutton, Sean; Kelekis, Alexis

2014-07-01

206

Fortuitously discovered liver lesions  

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The fortuitously discovered liver lesion is a common problem. Consensus might be expected in terms of its work-up, and yet there is none. This stems in part from the fact that there is no preventive campaign involving the early detection of liver tumors other than for patients with known liver cirrhosis and oncological patients. The work-up (detection and differential diagnosis) of liver tumors comprises theoretical considerations, history, physical examination, laboratory tests, standard ult...

Dietrich, Christoph F.; Malay Sharma; Gibson, Robert N.; Dagmar Schreiber-Dietrich; Christian Jenssen

2013-01-01

207

Asymptomatic ischemic cerebral lesions  

International Nuclear Information System (INIS)

For the purpose of studying the incidence, pathomorphology and etiology of asymptomatic ischemic cerebral lesions, we carried out a brain MRI study on 65 patients with diabetes mellitus accompanied with hypertension who are thought to belong to a high risk group of ischemic cerebrovascular diseases. Excluding the abnormality of tendon reflex due to diabetic neuropathy, sixty percent of the total patients had some mild neurological signs and symptoms, most of them was discrepancy in tendon reflex. The percentage of the patients in whom MRI disclosed some abnormalities was as high as 70%, they were lacunar stroke, multiple lacunar state, cortical infarct, and patchy high signal lesions visible only in the T2 weighted image. Lacunes or these patchy high signal lesions (considered to be the dilatation of the perivascular space or true lacunes) tended to be found along the border zone or the terminal zone. These results indicate that asymptomatic patients in whom MRI discloses the abnormalities should be considered as candidates for the future onset of multi-infarct. (author)

1988-01-01

208

Management of ampullary lesions.  

Science.gov (United States)

Adenomatous lesions of the ampulla of Vater are relatively rare neoplasms that raise many questions regarding standard management. Adenocarcinoma often will be found in ampullary lesions and should be treated by pancreaticoduodenectomy (PD). Benign-appearing adenomas may be treated by PD, transduodenal ampullectomy (AMP), or endoscopic ampullectomy (EA). AMP and EA have decreased morbidity and mortality compared with PD but are limited by concerns for appropriate resection margins, high recurrence rates, and the need for surveillance endoscopy or additional procedures. Preoperative endoscopic biopsies should be obtained to identify carcinoma, but they have high false-negative rates and cannot be relied upon to rule out malignancy. Intraoperative frozen section evaluation should be requested routinely during AMP, with conversion to PD if carcinoma is demonstrated. The gold standard management of benign adenomas has not been clarified, but the goal for all treatment modalities is complete resection. Patients with familial adenomatous polyposis may be exceptions to this, and routine surveillance endoscopy and biopsy with selective resection have been advocated by some as an alternative to complete resection. Adjuvant chemoradiation has a very limited role in the treatment of ampullary carcinoma and ideally should be offered in the setting of a clinical trial. Metastatic and locally advanced, unresectable lesions may be palliated by surgical or endoscopic bypass, as well as by celiac plexus blockade. PMID:16942661

Dittrick, George W; Mallat, Damien B; Lamont, Jeffrey P

2006-09-01

209

Three-dimensional morphology and bony range of movement in hip joints in patients with hip dysplasia.  

Science.gov (United States)

To confirm whether developmental dysplasia of the hip has a risk of hip impingement, we analysed maximum ranges of movement to the point of bony impingement, and impingement location using three-dimensional (3D) surface models of the pelvis and femur in combination with 3D morphology of the hip joint using computer-assisted methods. Results of computed tomography were examined for 52 hip joints with DDH and 73 normal healthy hip joints. DDH shows larger maximum extension (p = 0.001) and internal rotation at 90° flexion (p < 0.001). Similar maximum flexion (p = 0.835) and external rotation (p = 0.713) were observed between groups, while high rates of extra-articular impingement were noticed in these directions in DDH (p < 0.001). Smaller cranial acetabular anteversion (p = 0.048), centre-edge angles (p < 0.001), a circumferentially shallower acetabulum, larger femoral neck anteversion (p < 0.001), and larger alpha angle were identified in DDH. Risk of anterior impingement in retroverted DDH hips is similar to that in retroverted normal hips in excessive adduction but minimal in less adduction. These findings might be borne in mind when considering the possibility of extra-articular posterior impingement in DDH being a source of pain, particularly for patients with a highly anteverted femoral neck. PMID:24788490

Nakahara, I; Takao, M; Sakai, T; Miki, H; Nishii, T; Sugano, N

2014-05-01

210

Full-field displacement and strain measurement of small complex bony structures with digital speckle pattern interferometry and shearography  

Science.gov (United States)

We have developed a simple digital speckle pattern interferometry (DSPI) and shearography setup to measure the displacement and the corresponding strains of small complex bony structures. We choose both optical techniques because we want to obtain very small deformations (+/- 20 ?m) of small objects (+/- 1cm). Furthermore full field and in situ measurements are preferred. We first use a Michelson DSPI arrangement with phase shifting. In this way we can obtain the out-of-plane displacements precisely. Second, shearography is introduced to measure the derivative of the out-ofplane displacement. In this way some intrinsic disadvantages of DSPI can be overcome. We have developed these setups to measure the out-of-plane deformations of (small) bird beaks when realistic external forces are applied. In this way, we have a full field validation measurement to which we can compare the outcome of realistic finite element models. The aim is to determine whether the shape, and not only the size, of the bird beaks are optimized to deal with the biting forces that a species encounters. This quantitative analysis will help biologists to investigate if beak morphology is adapted to feeding habits. Applying the method to the famous evolution model of the Darwin's finches will provide scientific proof of functional evolution. In this paper we will present both the DSPI and shearography setup, a comparison of the performance of both techniques on a simple deflection of a cantilever beam and the first results obtained on loaded bird beaks.

Soons, Joris; Dirckx, Joris J. J.

2010-09-01

211

Acute periodontal lesions.  

Science.gov (United States)

This review provides updates on acute conditions affecting the periodontal tissues, including abscesses in the periodontium, necrotizing periodontal diseases and other acute conditions that cause gingival lesions with acute presentation, such as infectious processes not associated with oral bacterial biofilms, mucocutaneous disorders and traumatic and allergic lesions. A periodontal abscess is clinically important because it is a relatively frequent dental emergency, it can compromise the periodontal prognosis of the affected tooth and bacteria within the abscess can spread and cause infections in other body sites. Different types of abscesses have been identified, mainly classified by their etiology, and there are clear differences between those affecting a pre-existing periodontal pocket and those affecting healthy sites. Therapy for this acute condition consists of drainage and tissue debridement, while an evaluation of the need for systemic antimicrobial therapy will be made for each case, based on local and systemic factors. The definitive treatment of the pre-existing condition should be accomplished after the acute phase is controlled. Necrotizing periodontal diseases present three typical clinical features: papilla necrosis, gingival bleeding and pain. Although the prevalence of these diseases is not high, their importance is clear because they represent the most severe conditions associated with the dental biofilm, with very rapid tissue destruction. In addition to bacteria, the etiology of necrotizing periodontal disease includes numerous factors that alter the host response and predispose to these diseases, namely HIV infection, malnutrition, stress or tobacco smoking. The treatment consists of superficial debridement, careful mechanical oral hygiene, rinsing with chlorhexidine and daily re-evaluation. Systemic antimicrobials may be used adjunctively in severe cases or in nonresponding conditions, being the first option metronidazole. Once the acute disease is under control, definitive treatment should be provided, including appropriate therapy for the pre-existing gingivitis or periodontitis. Among other acute conditions affecting the periodontal tissues, but not caused by the microorganisms present in oral biofilms, infectious diseases, mucocutaneous diseases and traumatic or allergic lesions can be listed. In most cases, the gingival involvement is not severe; however, these conditions are common and may prompt an emergency dental visit. These conditions may have the appearance of an erythematous lesion, which is sometimes erosive. Erosive lesions may be the direct result of trauma or a consequence of the breaking of vesicles and bullae. A proper differential diagnosis is important for adequate management of the case. PMID:24738591

Herrera, David; Alonso, Bettina; de Arriba, Lorenzo; Santa Cruz, Isabel; Serrano, Cristina; Sanz, Mariano

2014-06-01

212

A disappearing neonatal skin lesion.  

LENUS (Irish Health Repository)

A preterm baby girl was noted at birth to have a firm, raised, non-tender skin lesion located over her right hip. She developed three similar smaller lesions on her ear, buttock and right knee. All lesions had resolved by 2 months of age.

Hawkes, Colin Patrick

2012-01-31

213

Herniation pits and cystic-appearing lesions at the anterior femoral neck: an anatomical study by MSCT and {mu}CT  

Energy Technology Data Exchange (ETDEWEB)

To determine distinguishing features between herniation pits (HPs) and other cystic-appearing lesions at the anterior femoral neck in multi-slice computed tomography (MSCT) and micro-computed tomography (microCT) examinations. Institutional review board approval was obtained to examine 37 proximal femora of 23 cadaveric specimens (mean age available in 19 cadavers, 83 years; range 68-100 years; 9 female, 8 male, 6 unknown). All 37 femora were investigated by MSCT. 23 femora, which revealed cystic-appearing lesions at the anterior femoral neck in MSCT examinations, were additionally examined by microCT. Cystic-appearing lesions were categorized by their location, sclerotic margin, demarcation and shape in MSCT with assessment of inter-observer agreement. Detailed cortical and trabecular properties were evaluated in microCT examinations. There were seven HPs in three femora. There were a number of abnormalities potentially imitating HPs, including focal osteoporosis (13 in 13 femora), degenerative changes (5 in 4 femora) and trabecular restructuring (5 in 4 femora) at the anterior femoral neck. HPs were differentiated on the basis of their subchondral/subcortical location, completely surrounding sclerosis, clear demarcation and round-to-oval shape in MSCT. Because of their location and their microscopic appearance, HPs seem to resemble intra-osseous ganglia at the anterior femoral neck. HPs have to be differentiated from other cystic appearing lesions at the anterior femoral neck to avoid overestimation of their incidence in the context of diagnosis of femoroacetabular impingement. (orig.)

Panzer, Stephanie; Esch, Ulrich [Trauma Center Murnau, Department of Radiology, Murnau (Germany); Abdulazim, Ahmed Nabil; Augat, Peter [Paracelsus University Salzburg and Trauma Center Murnau, Biomechanics Laboratory, Murnau (Germany)

2010-07-15

214

Lesiones deportivas / Sports injuries  

Scientific Electronic Library Online (English)

Full Text Available SciELO Colombia | Language: Spanish Abstract in spanish El estrés generado por la práctica deportiva ha originado una mayor probabilidad de que los atletas presenten lesiones agudas y crónicas. En el ámbito mundial existen diferentes investigaciones acerca de la incidencia de lesiones deportivas. La comparación de sus resultados es difícil por las difere [...] ncias en las características de la población y en la forma de reportar los datos, que varía ampliamente entre los estudios (proporciones o tasas de incidencia o tasas por cada 100 ó 1.000 participantes o tasas por horas de juego o por número de partidos jugados). Las tasas varían entre 1,7 y 53 lesiones por 1.000 horas de práctica deportiva, entre 0,8 y 90,9 por 1.000 horas de entrenamiento, entre 3,1 y 54,8 por 1.000 horas de competición y de 6,1 a 10,9 por 100 juegos. La gran variación entre las tasas de incidencia se explica por las diferencias existentes entre los deportes, los países, el nivel competitivo, las edades y la metodología empleada en los estudios. Se ha definido la lesión deportiva como la que ocurre cuando los atletas están expuestos a la práctica del deporte y se produce alteración o daño de un tejido, afectando el funcionamiento de la estructura. Los deportes de contacto generan mayor riesgo de presentar lesiones; se destacan al respecto los siguientes: fútbol, rugby, baloncesto, balonmano, artes marciales y jockey. Las lesiones ocurren con mayor probabilidad en las competencias que en el entrenamiento. Abstract in english Stress generated by sports practice has increased the probability that athletes suffer from acute and chronic injuries. Worldwide, there have been many different investigations concerning the incidence of sport injuries. The different ways in which results have been presented makes it difficult to c [...] ompare among them. Rates of sports injuries vary between 1.7 and 53 per 1.000 hours of sports practice; 0.8 and 90.9 per 1.000 hours of training; 3.1 and 54.8 per 1.000 hours of competition, and 6.1 and 10.9 per 100 games. The great variability among the incidence rates may be explained by differences among sports, countries, competitive levels, ages and methodology used in the studies. Sports injuries have been defined as those occurring when athletes are practicing sports and that result in tissue alterations or damages, affecting the operation of the corresponding structures. Contact sports such as soccer, rugby, martial arts, basketball, handball and hockey generate greater risk of injuries. The probability of lesions is higher during competition than in training.

JORGE ALBERTO, OSORIO CIRO; MÓNICA PAOLA, CLAVIJO RODRÍGUEZ; ELKIN, ARANGO V; SANTIAGO, PATIÑO GIRALDO; ISABEL CRISTINA, GALLEGO CHING.

215

Multiple bony metastases of breast cancer. Role of CA 15.3 and response to hormone therapy  

International Nuclear Information System (INIS)

Bone metastases are involved in a 65-75% of advanced metastatic breast cancer cases. Tumoral markers (CEA, CA 15.3) are useful in the follow-up and evaluation of response to treatment. Hormonal therapy is the optimal treatment option in low grade metastatic breast cancer due to low toxicity and general long term good response. We present a breast cancer case treated with surgery, chemotherapy and radiotherapy. The patient was asymptomatic during the follow-up and multiple bone metastases were diagnosed as a result of an increased CA 15.3 marker found. Hormone therapy was the recommended initial treatment with good response and tolerance. Bone lesions remained stabilized for 7 years but after treatment suspension new bone lesions appeared. CA 15.3 marker had increased again. Reintroduction of hormonal therapy achieved again the stabilization of the lesions

2012-01-01

216

The significance of a hypoplastic bony canal for the cochlear nerve in patients with sensorineural hearing loss: CT and MRI findings  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this study is to evaluate the significance of the hypoplastic canal for the cochlear nerve in patients with sensorineural hearing loss (SNHL) and the relationship between the hypoplastic bony canal and aplasia or hypoplasia of the cochlear nerve. A retrospective review of high resolution temporal CT(HRCT) and MRI findings was conducted. The narrow bony canal of the cochlear nerve and the relative size of the internal auditory canal were correlated with the cochlear nerve deficiency on MRI. The comparative size of the component nerves (facial, cochlear, superior vestibular, inferior vestibular nerve), and the relative size of the internal auditory canal and the bony canal of the cochlear nerve were measured. The clinical history and the results of the clinical examination were reviewed for each patient. High resolution MRI showed aplasia of the common vestibulocochlear nerve in one patient and a deficiency of the cochlear nerve in 9 patients. These abnormalities occurred in association with a prominent narrowing of the canal for the cochlear nerve and a stenosis of the internal auditory canal, which was observed on temporal bone CT in 9 patients with congenital SNHL. Three patients had normal IAC, despite the presence of a hypoplastic cochlear nerve on the side on which they had SNHL. In one patient, the narrowing of the canal for the cochlear nerve and internal auditory canal were not found to be associated with acquired SNHL. The hypoplastic bony canal for the cochlear nerve might be more highly indicative of congenital cochlear nerve deficiency than that of the narrow internal auditory canal, and the position of the crista falciformis should also be carefully.

Choi, Yoon Jung; Park, Sang Yoo; Kim, Myung Soon; Sung, Ki Jun [College of Medicine, Yonsei Univ., Wonju (Korea, Republic of)

2004-04-01

217

The significance of a hypoplastic bony canal for the cochlear nerve in patients with sensorineural hearing loss: CT and MRI findings  

International Nuclear Information System (INIS)

The purpose of this study is to evaluate the significance of the hypoplastic canal for the cochlear nerve in patients with sensorineural hearing loss (SNHL) and the relationship between the hypoplastic bony canal and aplasia or hypoplasia of the cochlear nerve. A retrospective review of high resolution temporal CT(HRCT) and MRI findings was conducted. The narrow bony canal of the cochlear nerve and the relative size of the internal auditory canal were correlated with the cochlear nerve deficiency on MRI. The comparative size of the component nerves (facial, cochlear, superior vestibular, inferior vestibular nerve), and the relative size of the internal auditory canal and the bony canal of the cochlear nerve were measured. The clinical history and the results of the clinical examination were reviewed for each patient. High resolution MRI showed aplasia of the common vestibulocochlear nerve in one patient and a deficiency of the cochlear nerve in 9 patients. These abnormalities occurred in association with a prominent narrowing of the canal for the cochlear nerve and a stenosis of the internal auditory canal, which was observed on temporal bone CT in 9 patients with congenital SNHL. Three patients had normal IAC, despite the presence of a hypoplastic cochlear nerve on the side on which they had SNHL. In one patient, the narrowing of the canal for the cochlear nerve and internal auditory canal were not found to be associated with acquired SNHL. The hypoplastic bony canal for the cochlear nerve might be more highly indicative of congenital cochlear nerve deficiency than that of the narrow internal auditory canal, and the position of the crista falciformis should also be carefully

2004-04-01

218

Morphometry and Variations of Bony Ponticles of the Atlas Vertebrae (C1) in Kenyans Morfometría y Variaciones de Puentes Óseos de la Vértebra Atlas (C1) en Kenianos  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Atlas bridges, the bony outgrowths over the third segment of the vertebral artery are associated with compression of the artery and nerves. There are limited studies comparing morphometry of the complete atlas bridges and that of the ipsilateral transverse foramen. Bilateral and gender differences in the morphometry of the complete bridges remain relatively unexplored. One hundred and two atlas vertebrae (49 male and 53 female) obtained from the Osteology Department of the National Museums of...

Karau Bundi, P.; Ogeng´o, J. A.; Hassanali, J.; Odula, P. O.

2010-01-01

219

Sector projection in computerized tomography of the orbit, 2. Comparison with the conventional method in the architecture of bony wall of the orbit  

Energy Technology Data Exchange (ETDEWEB)

Orbital CT was performed by slicing at 1.5 mm in width on cadaver skulls for comparison of the architectural images of the bony walls of the orbit by the conventional method with those by sector projection. The sector projection produced images superior to those by the conventional method, except for a slightly poor visualization of the neighborhood of the lower portion of infudibular tip of the orbit.

Nakamura, Y.; Kirisawa, I. (Toyama Medical and Pharmaceutical Univ. (Japan)); Umetani, T.; Tanaka, T.

1982-03-01

220

The posterior Monteggia lesion.  

Science.gov (United States)

Thirteen posterior Monteggia fracture-dislocations in adults were treated surgically at the Massachusetts General Hospital from 1980 to 1988. A characteristic lesion was observed, consisting of a proximal ulna fracture with a triangular or quandrangular fracture at or near the level of the coronoid, a posterior or posterolateral radiocapitellar dislocation, and, in 10 cases, a radial head fracture. Nine patients were women and four were men, with an average age of 56 years. Following reduction of the radiocapitellar dislocation, the ulnar fractures were treated with plates in each case. Seven fractured radial heads were excised, one replaced with a silicone prosthesis, and three treated by open reduction and internal fixation. The 11 surviving patients were observed using the performance index of Broberg and Morrey at an average follow-up time of 38.4 months. The conditions of three were rated excellent, three good, four fair, and one poor. Incomplete reduction of the ulnar fracture with residual posterior radiocapitellar subluxation was observed in four cases, all leading to loss of forearm supination. We believe this lesion to be more common than previously reported. Recognition of its specific anatomic features is essential to achieve a functional outcome. PMID:1761999

Jupiter, J B; Leibovic, S J; Ribbans, W; Wilk, R M

1991-01-01

 
 
 
 
221

Laboratory effect of Boni Protect containing Aureobasidium pullulans (de Bary Arnoud in the control of some fungal diseases of apple fruit  

Directory of Open Access Journals (Sweden)

Full Text Available The efficacy of Aureobasidium pullulans (in the biopreparation Boni Protect against different pathogens of apples (Botrytis cinerea, Monilinia fructigena, Penicillium expansum, and Pezicula malicorticis was evaluated under laboratory con- ditions. The biocontrol product was applied at concentrations of 0.05%, 0.1%, and 0.5%. Fruits of apple cultivars 'Jonagold Decosta' and 'Pinova' were used. Boni Protect was very effective against B. cinerea on cv. 'Jonagold Decosta', reducing disease incidence by 55–83.8%. On 'Pinova' apples, this biological control product was the most efficient at earlier stages of the experiment. It inhibited grey mold by 65% after 5 days from inoculation and only by 14% after 20 days. On cv. 'Jonagold Decosta', Boni Protect at a concentration of 0.1% was also effective against M. fructigena, reducing brown rot by 31.4–74.5%, but its efficiency on cv. 'Pinova' was not significant. Blue mold caused by P. expansum was inhibited only slightly by the biocontrol product, while P. malicorticis proved to be the most resistant to its antagonistic abilities.

Anna Wagner

2013-04-01

222

Bony regeneration effect of electron-beam irradiated hydroxyapatite and tricalcium phosphate mixtures with 7 to 3 ratio in the caravel defect model of rat  

International Nuclear Information System (INIS)

The aim of this study is to evaluate the effect and potential of electron beam irradiation treatment to the new bone formation in the rat calvarial bony defects by using of 7 to 3 ratios of hydroxyapatite and tricalcium phosphate mixed with type I collagen. We used 1.0 MeV linear accelerator and 2.0 MeV superconductive linear accelerator with different irradiation dose, such as 1, 30, 60 kGy. And 10.0 MeV high frequency superconductive linear accelerator was also used. In six different experimental groups, the defect of every three rate was filled with E-beam irradiated bony mixtures, which different energy and dose, and that of rats without E-beam irradiated bony mixtures can be compared with out previous results. The other three rats were used as sham group. Rats were sacrificed after 4, 8, and 16 weeks, and grafted healing specimens were studied by clinical and radiographic findings, histomorphologic staining with hematoxylin and eosin. The large particular size of HLA was changed to small particles after E-beam irradiation, to which small particle of TEPC was engaged to small sexed HLA with organic collagen components in Seam findings. Abundant endothelial cells with preciosity were found around inner portions of grafted healing bone and many couplings of osteoblast with osteoclast in Tem findings were found in every experimental groups

2011-03-25

223

Bony regeneration effect of electron-beam irradiated hydroxyapatite and tricalcium phosphate mixtures with 7 to 3 ratio in the caravel defect model of rat  

Energy Technology Data Exchange (ETDEWEB)

The aim of this study is to evaluate the effect and potential of electron beam irradiation treatment to the new bone formation in the rat calvarial bony defects by using of 7 to 3 ratios of hydroxyapatite and tricalcium phosphate mixed with type I collagen. We used 1.0 MeV linear accelerator and 2.0 MeV superconductive linear accelerator with different irradiation dose, such as 1, 30, 60 kGy. And 10.0 MeV high frequency superconductive linear accelerator was also used. In six different experimental groups, the defect of every three rate was filled with E-beam irradiated bony mixtures, which different energy and dose, and that of rats without E-beam irradiated bony mixtures can be compared with out previous results. The other three rats were used as sham group. Rats were sacrificed after 4, 8, and 16 weeks, and grafted healing specimens were studied by clinical and radiographic findings, histomorphologic staining with hematoxylin and eosin. The large particular size of HLA was changed to small particles after E-beam irradiation, to which small particle of TEPC was engaged to small sexed HLA with organic collagen components in Seam findings. Abundant endothelial cells with preciosity were found around inner portions of grafted healing bone and many couplings of osteoblast with osteoclast in Tem findings were found in every experimental groups.

Kim, Soung Min; Eo, Mi Young; Kang, Ji Young; Myoung, Hoon; Lee, Jong Ho [Seoul National Univ., Seoul (Korea, Republic of); Cho, Hye Jin [Korea Basic Science Institute, Daejeon (Korea, Republic of); Yea, Kwon Hae; Lee, Byung Cheol [Korea Atomic Research Institute, Daejeon (Korea, Republic of)

2011-07-01

224

Radiographic features of large cystic lesions of the jaws in children  

Energy Technology Data Exchange (ETDEWEB)

The surgical approach to cystic lesions of the jaws is either marsupialisation or enucleation. The treatment of choice is dependent on the size of the lesion, the bony integrity of the cyst and its proximity to anatomical structures.Objectives. To assess large (>2.0 cm) cystic lesions of the jaws using plain film radiography (PFR), CT, multiplanar reconstruction program (MPR) and three-dimensional CT (3D-CT).Patients and methods. Twelve children aged 7-14 years.Results. The classic radiological feature was a unilocular radiolucent area surrounded by a well-defined radio-opaque margin adjacent to the root of a non-viable tooth or associated with the crown of an unerupted tooth. Malposition of teeth and root resorption were more common in dentigerous cysts. The features seen on CT were clear and more precise than those seen on PFR. MPR, by the three-dimensional visualisation of the jaw (axial, panoramic, and bucco-lingual), provided useful information for determining the outline of the cyst and its proximity to adjacent anatomical structures, such as teeth, nerves or maxillary sinus. 3-D CT further and more clearly demonstrated discontinuity in the buccal or palatal/lingual cortices of the jaw bone. PFR was very accurate in determining root resorption.Conclusions. CT with MPR and, ideally, 3-D CT should be used for the comprehensive diagnostic work-up and meticulous surgical management of large cystic lesions of the jaws in children. (orig.)

Bodner, Lipa; Woldenberg, Yitzhak [Department of Oral and Maxillofacial Surgery, Soroka Medical Center, P.O. Box 151, Beer-Sheva 84101 (Israel); Bar-Ziv, Jacob [Department of Radiology, Hebrew University and Hadassab School of Medicine, Jerusalem (Israel)

2003-01-01

225

Lesiones traumáticas: Conducta odontológica  

Scientific Electronic Library Online (English)

Full Text Available SciELO Venezuela | Language: Spanish Abstract in spanish En la cavidad bucal se pueden producir una variedad de lesiones de diferente etiología, por ello es muy importante que el odontólogo las identifique y conozca las consecuencias que ocasiona si no se previenen o tratan a tiempo. Se funda como premisa que el cuidado periodontal es, en esencia, labor d [...] el odontólogo general y que éste no puede pasar por alto la responsabilidad de proveer atención a todos los pacientes. La incidencia excesivamente elevada de los problemas periodontales entre la población, dificulta que un número reducido de especialistas los pueda enfrentar. Asimismo, el estrecho vínculo entre los tratamientos dentales restaurativos y los regímenes periodontales hace muy importante que el odontólogo general disponga de conocimientos a fondo sobre periodoncia. En la cavidad bucal se producen variedades de lesiones de origen traumático ya sea por injurias químicas, físicas y térmicas estás representan una urgencia en Odontología. El propósito de este reporte es describir las diferentes presentaciones clínicas de dicha patología, su etiología, diagnósticos diferenciales y diferentes métodos de tratamiento, para valorar sus complicaciones y cuidados postoperatorios. Para ello se realizó basado en los lineamientos de la investigación descriptiva documental, una revisión de la literatura nacional e internacional. Abstract in english A variety of different etiologies pathologies can affect the oral cavity, due to this reason, dentists must be able to identify them and their consequences if they are not treated on time. It is primordial for the general practitioner dentists the periodontal care of their patients. Among the popula [...] tion the periodontal diseases are very common and only a reduced number of specialists can treat them. The close relation between restorative dental treatments and periodontal treatment procedures lead to the tendency that de general practitioner has enough knowledge in the periodontal field. Among the variety of pathologic entities that affect the oral mucosa, that presents as ulcer and are really Traumatic lesions in its different types chemical injury, physical injury, thermal injury It is considered one of the emergencies in dentistry. Dentist must be able to recognize and treat them. The purpose of this research is to describe the possible etiologic agents, clinical features and treatment of this disease and also to recommend the multidisciplinary attention to these patient. For this paper was made a study based on the lineaments of the descriptive documental research, mainly with scientific bibliographic references literature national and international.

Yuni J, Salinas M; Ronald E, Millán I; Juan C, León M.

226

[Craniofacial granulomatous lesions].  

Science.gov (United States)

Granulomatous lesions of the cranio-facial area are frequent and various in their nature: lymphohistiocytic with or without eosinophils, tuberculoid-like with epithelioid and giant cells, or sometimes made essentially of giant cells. Their etiology can be known or easy to find: foreign body granuloma, sarcoidosis, leprosy, rhinoscleroma, fungal diseases especially zygomycosis and rhinosporidiosis, parasitic diseases. The lethal midline granuloma is a clinical entity characterized by its necrotic and relentlessly progressive destructive presentation. After elimination of a malignant process, especially lymphoid, and of a Wegener's granulomatosis the diagnosis will be "idiopathic midline non-healing granuloma". Some of them will stay located at the facial area; others will disseminate as a malignant disease. Central giant cell granuloma and histiocytosis X, especially eosinophilic granuloma, are two other varieties of granuloma, different of the former granulomatous infiltrates by their clinical presentation and their evolution. PMID:3521624

Brocheriou, C; de Roquancourt, A; D'Agay, M F

1986-01-01

227

Mycetoma: Nonvenereal perineal lesions.  

Science.gov (United States)

Mycetoma is a chronic, granulomatous disease of the skin, and subcutaneous tissue, which sometimes involves muscle, bones, and neighboring organs. It is characterized by tumefaction, abscess formation, and fistulae with discharge of grains from sinuses. Mycetoma can be caused by various species of fungi (eumycetoma) and aerobic actinomycetes (actinomycetoma), which occur as saprophytes in soil or plants. A tentative diagnosis sufficient to initiate treatment may be made on the basis of grain color. For instance, melanoid grains are always caused by fungi and ochroid or pale grains by actinomycetes. Although this is not the thumbrule, there are exceptional reports too. As trauma favors infection, most lesions are on the foot and lower leg but they may occur anywhere on the body mimicking actinomycosis. However, lab investigations and culture are important tool to differentiate apart from the clinical picture. We are reporting atypical case with unusual site of presentation (perineum and thigh) of mycetoma. PMID:21808436

Gupta, Shweta; Jain, Khushbu; Parmar, Chirag; Shah, Parul; Raval, Ranjan C

2010-01-01

228

Mycetoma: Nonvenereal perineal lesions  

Directory of Open Access Journals (Sweden)

Full Text Available Mycetoma is a chronic, granulomatous disease of the skin, and subcutaneous tissue, which sometimes involves muscle, bones, and neighboring organs. It is characterized by tumefaction, abscess formation, and fistulae with discharge of grains from sinuses. Mycetoma can be caused by various species of fungi (eumycetoma and aerobic actinomycetes (actinomycetoma, which occur as saprophytes in soil or plants. A tentative diagnosis sufficient to initiate treatment may be made on the basis of grain color. For instance, melanoid grains are always caused by fungi and ochroid or pale grains by actinomycetes. Although this is not the thumbrule, there are exceptional reports too. As trauma favors infection, most lesions are on the foot and lower leg but they may occur anywhere on the body mimicking actinomycosis. However, lab investigations and culture are important tool to differentiate apart from the clinical picture. We are reporting atypical case with unusual site of presentation (perineum and thigh of mycetoma.

Gupta Shweta

2010-01-01

229

Intravascular lesions of the hand  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Introduction Intravascular lesions of the hand comprise reactive and neoplastic entities. The clinical diagnosis of such lesions is often difficult, and usually requires pathologic examination. We present the largest series to date of intravascular lesions affecting the hand. Methods A retrospective review of intravascular (arterial and venous lesions involving the hand was conducted. Data regarding clinicopathologic findings were analyzed. Results We identified 10 patients with intravascular lesions of their hands including thromboemboli (n = 3, reactive intravascular conditions such as papillary endothelial hyperplasia or Masson's tumor (n = 2 and fasciitis (n = 1, as well as vascular neoplasms including pyogenic granuloma (n = 2 and angioleiomyoma (n = 2. Conclusion Blood vessel injury and/or venous thrombosis may predispose to several intravascular lesions of the hand. Recognition of reactive entities from neoplastic conditions is important.

Duke Wayne H

2008-05-01

230

Anatomical and Bone Scintigraphy Radiology: Report of the Overlap of Images in the Therapeutic Approach to Bone Lesions  

International Nuclear Information System (INIS)

Conventional radiology, Rx simple or tomographic studies is part of the initial study of bone lesions or suspicion of them in the daily management of patients. The bone scan is a procedure widely used as an adjunct to diagnosis in extensive study of these cases, providing global skeletal metabolic information, which mainly includes the diagnosis of skeletal metastases in malignant tumors. Objective: To evaluate the overlap of anatomical and functional images in the medical management of surgical bone lesions. Materials and methods: Prospectively included 40 patients of various age groups, referred to Gamanuclear Ltd from October 2005 to April 2007, which were studied by bony growths (35) or suspected of same by focusing painful symptomatology (5). All patients had radiological studies. The bony scintigraphy were performed 3-4 hours after intravenous injection of a diagnostic dose of 99mTc MDP. The gamacamaras used was a GE XRT and other SMV Power Vision, and the overlap of images is done with Corel draw, screen hunter and Scion image

2008-07-01

231

Treatment of the femoral neck amd trochanteric benign lesions.  

Science.gov (United States)

Thirty-five patients with a benign lesion of the femoral neck or trochanter were treated and seen in followup at the authors' institution from 1988 to 1991. Sixteen men and 19 women between the ages of 18 and 54 years (average, 27 years) were seen at an average followup of 3 years 6 months (range, 2-5 years). Eight patients had aneurysmal bone cyst; 14 had monostotic fibrous dysplasias; 2 had giant cell tumors; and 11 had simple bone cysts. Eleven patients had pathologic fractures. All patients were treated with curettage and bone grafting in conjunction with a sliding hip compression screw and plate. The bone grafting included a combination of a deep frozen allogenic cortical strut with autogenous iliac cancellous bone to fill the remaining defect space after lag screw and cortical strut had been implanted. At followup, all patients had good bony healing and incorporation of the implanted graft. There were no complications and no local recurrences. All of the functional results were excellent. PMID:8653960

Shih, H N; Cheng, C Y; Chen, Y J; Huang, T J; Hsu, R W

1996-07-01

232

Air CT cisternography in cases with retrolabyrinthine lesion  

International Nuclear Information System (INIS)

Imaging of the cerebellopontine angle structures by means of air CT cisternography was studied in cases with suspected retrolabyrinthine lesions. The method of air CT cisternography in our study was characterized by air infusion through a suboccipital route and by imaging of both cerebellopontine angles in one study. Ninety cases have been studied so far. Four cases of small acoustic tumors, including two cases of intracanalicular tumors, were found. Additionally, one case of small meningioma in the porus was detected. The percentage of the detection of small acoustic tumors in our series was significantly low. However, various abnormalities other than neoplasms were revealed. An enlargement of the acoustic canal without a tumor was found in five cases; this abnormality was usually bilateral. This structural abnormality corresponds to the patulous canal or dural ectasia of the canal described in the previous literature, which was believed to be one of characteristics of bony changes in Recklinghausen's disease. Only one case in our series, however, had the definite stigmata of Recklinghausen's disease. The present authors designate this canal enlargement ''empty meatus''; it seems to be a new clinical entity. An irregular thickening of the nerve and a nodular appearance of the nerve in the canal were found in the case of Recklinghausen's disease. A diagnosis of localized arachnoiditis was made in three cases, and that of a primary atrophy of the acoustic nerve, in one case. (author)

1986-01-01

233

Nonsurgical management of periapical lesions  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Periapical lesions develop as sequelae to pulp disease. They often occur without any episode of acute pain and are discovered on routine radiographic examination. The incidence of cysts within periapical lesions varies between 6 and 55%. The occurrence of periapical granulomas ranges between 9.3 and 87.1%, and of abscesses between 28.7 and 70.07%. It is accepted that all inflammatory periapical lesions should be initially treated with conservative nonsurgical procedures. ...

Fernandes Marina; Ataide Ida

2010-01-01

234

Preneoplastic lesions of the lung  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Lung cancer is the leading cause of cancer deaths worldwide. If we can define and detect preneoplastic lesions, we might have a chance of improving survival. The World Health Organization has defined three preneoplastic lesions of the bronchial epithelium: squamous dysplasia/carcinoma in situ; atypical adenomatous hyperplasia; and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia. These lesions are believed to progress to squamous cell carcinoma, adenocarcinoma and carcinoid tumors, respectively. In this review we summarize the data supporting the preneoplastic nature of these lesions, and delve into some of the genetic changes found in atypical adenomatous hyperplasia and squamous dysplasia/carcinoma in situ.

Yee Herman

2002-04-01

235

Computed tomography analysis of primary bone tumors: The significance in the evaluation of destructive lesions of pelvic bone  

International Nuclear Information System (INIS)

In a study of 20 primary tumors of osseous pelvis proven pathologically, computed tomographic appearance was analysed and correlated with the conventional radiographic appearance in terms of destructive patterns, tumor-bone margins, internal architectures, periosteal reaction and extents of the tumors. CT was invaluable for the assessment of the extent of tumors / associated extraosseous soft tissue masses and the detection of the internal matrix within the tumor. We found the additional information about the extent of soft tissue mase in 4 cases (20%) and about the internal matrix in 5 cases (25%). According to the analysis of the patterns of cortical transgression, grade III was absent in benignanacy, but in 6 cases of malignant tumors. CT is less useful in the evaluation of the periosteal reaction and tumor-bone margin in flat bony lesions, not tumor-soft tissue margins. Certain types of tumor behavior characterizing the lesions under discussion may be helpful in diagnosis.

1988-08-01

236

Fortuitously discovered liver lesions  

Directory of Open Access Journals (Sweden)

Full Text Available The fortuitously discovered liver lesion is a common problem. Consensus might be expected in terms of its work-up, and yet there is none. This stems in part from the fact that there is no preventive campaign involving the early detection of liver tumors other than for patients with known liver cirrhosis and oncological patients. The work-up (detection and differential diagnosis of liver tumors comprises theoretical considerations, history, physical examination, laboratory tests, standard ultrasound, Doppler ultrasound techniques, contrast-enhanced ultrasound (CEUS, computed tomography and magnetic resonance imaging, as well as image-guided biopsy. CEUS techniques have proved to be the most pertinent method; these techniques became part of the clinical routine about 10 years ago in Europe and Asia and are used for a variety of indications in daily clinical practice. CEUS is in many cases the first and also decisive technical intervention for detecting and characterizing liver tumors. This development is reflected in many CEUS guidelines, e.g., in the European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB guidelines 2004, 2008 and 2012 as well as the recently published World Federation for Ultrasound in Medicine and Biology-EFSUMB guidelines 2012. This article sets out considerations for making a structured work-up of incidental liver tumors feasible.

Christoph F Dietrich

2013-01-01

237

Nonsurgical management of periapical lesions  

Directory of Open Access Journals (Sweden)

Full Text Available Periapical lesions develop as sequelae to pulp disease. They often occur without any episode of acute pain and are discovered on routine radiographic examination. The incidence of cysts within periapical lesions varies between 6 and 55%. The occurrence of periapical granulomas ranges between 9.3 and 87.1%, and of abscesses between 28.7 and 70.07%. It is accepted that all inflammatory periapical lesions should be initially treated with conservative nonsurgical procedures. Studies have reported a success rate of up to 85% after endodontic treatment of teeth with periapical lesions. A review of literature was performed by using electronic and hand searching methods for the nonsurgical management of periapical lesions. Various methods can be used in the nonsurgical management of periapical lesions: the conservative root canal treatment, decompression technique, active nonsurgical decompression technique, aspiration-irrigation technique, method using calcium hydroxide, Lesion Sterilization and Repair Therapy, and the Apexum procedure. Monitoring the healing of periapical lesions is essential through periodic follow-up examinations.

Fernandes Marina

2010-01-01

238

Endoscopic approach to subepithelial lesions  

Science.gov (United States)

Endoscopy and endoscopic ultrasound (EUS) play a critical role in the detection and management of subepithelial lesions of the gastrointestinal tract. The most common subepithelial lesions detected by endoscopists are gastrointestinal stromal tumors (GISTs), leiomyomas, lipomas, granular cell tumors (GCTs), pancreatic rests and carcinoid tumors. These lesions can be classified based on unique histochemical staining and the gastrointestinal layer of origin. While the majority of the lesions are considered benign, some tumors such as GISTs and carcinoids have a strong propensity for malignant transformation. Therefore, appropriate endoscopic versus surgical management based on size and location is crucial in the prevention of malignant transformation and metastasis. In this review, we provide a systematic approach to the diagnosis, management and treatment of commonly encountered subepithelial lesions.

Menon, Laila

2014-01-01

239

Lesions of the long head of the biceps brachii - causations and assessment with imaging modalities (sonography, X-ray, arthrography, CT)  

International Nuclear Information System (INIS)

Because of unusual anatomy and function the long head of the biceps brachii (LHB) is often subject to pathologic changes. On reviewing 354 sonographies of the shoulder (7.5 MHz), it was found that 61 (=17%) abnormal findings of the LHB were reported such as degenerative changes accompanying impingement stadium II and III (atrophy, hypertrophy, effusion), intracapsular ruptures, acute isolated tenosynovities and bony changes of the sulcus (bony spurs, shallow and dysplastic sulcus with subluxation of the LHB). Each abnormal finding was confirmed by X-ray and arthrography (some via CT) and compared with sonographic report. There seems to be a strikingly high percentage of rotator cuff tears connected with lesions of the LHB and the reduced filling of the sheath of the LHB, if combined lesions were apparent elsewhere in the shoulder. We consider sonography to be the method of choice in the assessment of LHB injuries; in case of a verified lesion of the LHB, other pathologic conditions elsewhere in the shoulder are likely. (orig.)

1989-01-01

240

Lesion margin analysis for automated classification of cervical cancer lesions  

Science.gov (United States)

Digital colposcopy is an emerging technology, replacing the traditional colposcope for diagnosis of cervical lesions. Incorporating automated algorithms within a digital colposcopy system can improve the reliability and the diagnostic accuracy of cervical precancer and cancer. An automated computer-aided diagnosis (CAD) system can assess the three important cervical diagnostic cues: the color, the vascular patterns and the lesion margins with quantitative measures, similar to the way colposcopists use the Reid's index in traditional colposcopy. In this work we present a novel way to analyze and classify the global and the local features of one of the three major components in colposcopy diagnosis - the lesion margins. The margins of cervical lesion can be described as 'feathered,' 'geographic,' 'satellite,' 'regular or smooth' and 'margin-in-margin,' or they can be of mixed type. As margin characterization is a complex task, we use irregularity descriptors such as compactness indices and curvature descriptors. To address the complexity of the problem, the dependency of scale and the position of the lesion on the cervical image, our method use novel Fourier energy descriptors. The conceptually complex analysis of describing lesions as 'satellite' lesions or lesions with multiple margins is performed using descriptors, where the distance, the position and the local statistical estimates of image intensity play important role. We trained this new algorithm to classify and diagnose the cervix, evaluating only the lesions. The accuracy of the results is assessed against a 'ground truth' scheme, using colposcopists' annotations and pathology results. We report the resulted accuracy of the classification method assessed against this scheme.

Van Raad, Viara; Xue, Zhiyun; Lange, Holger

2006-03-01

 
 
 
 
241

Scales and dermal skeletal histology of an early bony fish Psarolepis romeri and their bearing on the evolution of rhombic scales and hard tissues.  

Science.gov (United States)

Recent discoveries of early bony fishes from the Silurian and earliest Devonian of South China (e.g. Psarolepis, Achoania, Meemannia, Styloichthys and Guiyu) have been crucial in understanding the origin and early diversification of the osteichthyans (bony fishes and tetrapods). All these early fishes, except Guiyu, have their dermal skeletal surface punctured by relatively large pore openings. However, among these early fishes little is known about scale morphology and dermal skeletal histology. Here we report new data about the scales and dermal skeletal histology of Psarolepis romeri, a taxon with important implications for studying the phylogeny of early gnathostomes and early osteichthyans. Seven subtypes of rhombic scales with similar histological composition and surface sculpture are referred to Psarolepis romeri. They are generally thick and show a faint antero-dorsal process and a broad peg-and-socket structure. In contrast to previously reported rhombic scales of osteichthyans, these scales bear a neck between crown and base as in acanthodian scales. Histologically, the crown is composed of several generations of odontodes and an irregular canal system connecting cylindrical pore cavities. Younger odontodes are deposited on older ones both superpositionally and areally. The bony tissues forming the keel of the scale are shown to be lamellar bone with plywood-like structure, whereas the other parts of the base are composed of pseudo-lamellar bone with parallel collagen fibers. The unique tissue combination in the keel (i.e., extrinsic Sharpey's fibers orthogonal to the intrinsic orthogonal sets of collagen fibers) has rarely been reported in the keel of other rhombic scales. The new data provide insights into the early evolution of rhombic (ganoid and cosmoid) scales in osteichthyans, and add to our knowledge of hard tissues of early vertebrates. PMID:23585902

Qu, Qingming; Zhu, Min; Wang, Wei

2013-01-01

242

Scales and Dermal Skeletal Histology of an Early Bony Fish Psarolepis romeri and Their Bearing on the Evolution of Rhombic Scales and Hard Tissues  

Science.gov (United States)

Recent discoveries of early bony fishes from the Silurian and earliest Devonian of South China (e.g. Psarolepis, Achoania, Meemannia, Styloichthys and Guiyu) have been crucial in understanding the origin and early diversification of the osteichthyans (bony fishes and tetrapods). All these early fishes, except Guiyu, have their dermal skeletal surface punctured by relatively large pore openings. However, among these early fishes little is known about scale morphology and dermal skeletal histology. Here we report new data about the scales and dermal skeletal histology of Psarolepis romeri, a taxon with important implications for studying the phylogeny of early gnathostomes and early osteichthyans. Seven subtypes of rhombic scales with similar histological composition and surface sculpture are referred to Psarolepis romeri. They are generally thick and show a faint antero-dorsal process and a broad peg-and-socket structure. In contrast to previously reported rhombic scales of osteichthyans, these scales bear a neck between crown and base as in acanthodian scales. Histologically, the crown is composed of several generations of odontodes and an irregular canal system connecting cylindrical pore cavities. Younger odontodes are deposited on older ones both superpositionally and areally. The bony tissues forming the keel of the scale are shown to be lamellar bone with plywood-like structure, whereas the other parts of the base are composed of pseudo-lamellar bone with parallel collagen fibers. The unique tissue combination in the keel (i.e., extrinsic Sharpey's fibers orthogonal to the intrinsic orthogonal sets of collagen fibers) has rarely been reported in the keel of other rhombic scales. The new data provide insights into the early evolution of rhombic (ganoid and cosmoid) scales in osteichthyans, and add to our knowledge of hard tissues of early vertebrates.

Qu, Qingming; Zhu, Min; Wang, Wei

2013-01-01

243

Mallory-Weiss lesions  

DEFF Research Database (Denmark)

Introduction: Malory-Weiss syndrome (MW) has been known since 1929. Only few studies exist which focus on the prognosis of the lesion. No Danish MW data are available. The purpose of the study was to describe the demographics of patients admitted with an MW to a Danish surgical unit during a 5-year period and to investigate the prognosis of these patients. Material and methods: Data from the patient records of 49 patients with endoscopically verified MW admitted through a five-year period were analysed. At follow-up, 35 patients were alive and contacted. A total of 29 responded. The mean time to follow-up from admittance was 42.7 months (range: 10.1-77.1). Results: Haemostasis was achieved in all 49 patients. Sixteen received active therapy during the endoscopic procedure. Haemoglobin at admitance was lower (p = 0.008), the presence of bleeding stigmata higher (p < 0.0001) and the number of patients receiving blood transfusion higher (p = 0.01) among those receiving active therapy than among the group receiving no therapy at the time of their endoscopy. At follow-up, 50% of those receiving active therapy were dead (eight of 16) compared with 18% (six of 33) in the no-therapy group (p = 0.02). In the follow-up period, 10% of the patients admitted with an MW were re-admitted for a new gasatrointestinal bleeding. Conclusion: Our data suggests that an attitude change is needed toward MW with bleeding stigmata. The course of the disease may not be as benign as generally believed. Further prospective studies designed to resolve this matter are needed.

Lange, J.; Jensen, Lone Susanne

2010-01-01

244

Comparison of prostate set-up accuracy and margins with off-line bony anatomy corrections and online implanted fiducial-based corrections  

International Nuclear Information System (INIS)

Full text: The aim of the study was to determine prostate set-up accuracy and set-up margins with off-line bony anatomy-based imaging protocols, compared with online implanted fiducial marker-based imaging with daily corrections. Eleven patients were treated with implanted prostate fiducial markers and online set-up corrections. Pretreatment orthogonal electronic portal images were acquired to determine couch shifts and verification images were acquired during treatment to measure residual set-up error. The prostate set-up errors that would result from skin marker set-up, off-line bony anatomy-based protocols and online fiducial marker-based corrections were determined. Set-up margins were calculated for each set-up technique using the percentage of encompassed isocentres land a margin recipe. The prostate systematic set-up errors in the medial-lateral, superior-inferior and anterior-I posterior directions for skin marker set-up were 2.2, 3.6 and 4.5 mm (1 standard deviation). For our bony anatomy-I based off-line protocol the prostate systematic set-up errors were 1.6, 2.5 and 4.4 mm. For the online fiducial based set-up the results were 0.5, 1.4 and 1.4 mm. A prostate systematic error of 10.2 mm was uncorrected by the off-line bone protocol in one patient. Set-up margins calculated to encompass 98% of prostate set-up shifts were 111-14 mm with bone off-line set-up and 4-7 mm with online fiducial markers. Margins from the van Herk margin I recipe were generally 1-2 mm smaller. Bony anatomy-based set-up protocols improve the group prostate set-up error compared with skin marks; however, large prostate systematic errors can remain undetected or systematic (errors increased for individual patients. The margin required for set-up errors was found to be 10-15 mm unless I implanted fiducial markers are available for treatment guidance.

2008-10-01

245

A combined bony and soft-tissue tarsal stabilization procedure (Grice-Schede) for hindfoot valgus in children with cerebral palsy.  

Science.gov (United States)

This study deals with a combined bony and soft-tissue procedure (Grice-Schede) for the treatment of pes (equino) planovalgus in children suffering from cerebral palsy. Results of 43 treated feet in 28 children were assessed clinically and radiologically at a mean follow-up time of 6.7 years (range from 0.6 years to 13.8 years). In all, 58.1% excellent or good results, 14.0% satisfactory and 27.9% poor results were found. The procedure can be recommended for patients with hemiplegic and diplegic conditions. It is not suited for patients with total body involvement. PMID:7946813

Hamel, J; Kissling, C; Heimkes, B; Stotz, S

1994-01-01

246

Distance-to-Agreement Investigation of Tomotherapy's Bony Anatomy-Based Autoregistration and Planning Target Volume Contour-Based Optimization  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To compare Tomotherapy's megavoltage computed tomography bony anatomy autoregistration with the best achievable registration, assuming no deformation and perfect knowledge of planning target volume (PTV) location. Methods and Materials: Distance-to-agreement (DTA) of the PTV was determined by applying a rigid-body shift to the PTV region of interest of the prostate from its reference position, assuming no deformations. Planning target volume region of interest of the prostate was extracted from the patient archives. The reference position was set by the 6 degrees of freedom (dof)—x, y, z, roll, pitch, and yaw—optimization results from the previous study at this institution. The DTA and the compensating parameters were calculated by the shift of the PTV from the reference 6-dof to the 4-dof—x, y, z, and roll—optimization. In this study, the effectiveness of Tomotherapy's 4-dof bony anatomy–based autoregistration was compared with the idealized 4-dof PTV contour-based optimization. Results: The maximum DTA (maxDTA) of the bony anatomy-based autoregistration was 3.2 ± 1.9 mm, with the maximum value of 8.0 mm. The maxDTA of the contour-based optimization was 1.8 ± 1.3 mm, with the maximum value of 5.7 mm. Comparison of Pearson correlation of the compensating parameters between the 2 4-dof optimization algorithms shows that there is a small but statistically significant correlation in y and z (0.236 and 0.300, respectively), whereas there is very weak correlation in x and roll (0.062 and 0.025, respectively). Conclusions: We find that there is an average improvement of approximately 1 mm in terms of maxDTA on the PTV going from 4-dof bony anatomy-based autoregistration to the 4-dof contour-based optimization. Pearson correlation analysis of the 2 4-dof optimizations suggests that uncertainties due to deformation and inadequate resolution account for much of the compensating parameters, but pitch variation also makes a statistically significant contribution.

Suh, Steve, E-mail: ssuh@coh.org [Division of Radiation Oncology, City of Hope National Medical Center, Duarte, California (United States); Schultheiss, Timothy E. [Division of Radiation Oncology, City of Hope National Medical Center, Duarte, California (United States)

2013-03-01

247

The added value of multislice SPECT/CT in patients with equivocal bony metastasis from carcinoma of the prostate  

International Nuclear Information System (INIS)

The purpose of this study was to investigate the additional value of single photon emission computed tomography/computed tomography (SPECT/CT) over whole-body planar bone scintigraphy and SPECT in prostate cancer patients in terms of diagnostic confidence, inter-reviewer agreement and the possible impact on the clinical management. This was a retrospective review of 40 consecutive prostate cancer patients (mean age 71 years) who underwent 99mTc-methylene diphosphonate (MDP) whole-body planar bone scintigraphy, SPECT and SPECT/CT between April 2006 and April 2008. The images were evaluated by two independent reviewers; inter-reviewer agreement was evaluated using a weighted kappa score. Each focus of abnormal increased tracer uptake was recorded using a 4-point diagnostic confidence scale. Institutional Review Board approval was obtained. Fifty lesions on planar bone scintigraphy in the 40 patients were evaluated. On reporting the planar study and SPECT scans, reviewers rated 61% of lesions as equivocal. On reporting the SPECT/CT scans only 8% of lesions were rated as equivocal, 24% were rated as malignant and 68% as benign. Weighted kappa scores for inter-reviewer agreement were 0.43 for bone scintigraphy, 0.56 for SPECT and 0.87 for SPECT/CT. All were significant at p < 0.0001. Follow-up imaging confirmed the SPECT/CT diagnoses in 14 patients. The addition of SPECT/CT resulted in a significant reduction of equivocal reports; a definitive diagnosis was given in the majority of the patients due to the improved diagnostic confidence compared to planar or SPECT imaging alone in prostate cancer patients with suspected bone metastases. (orig.)

2010-04-01

248

The added value of multislice SPECT/CT in patients with equivocal bony metastasis from carcinoma of the prostate  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this study was to investigate the additional value of single photon emission computed tomography/computed tomography (SPECT/CT) over whole-body planar bone scintigraphy and SPECT in prostate cancer patients in terms of diagnostic confidence, inter-reviewer agreement and the possible impact on the clinical management. This was a retrospective review of 40 consecutive prostate cancer patients (mean age 71 years) who underwent {sup 99m}Tc-methylene diphosphonate (MDP) whole-body planar bone scintigraphy, SPECT and SPECT/CT between April 2006 and April 2008. The images were evaluated by two independent reviewers; inter-reviewer agreement was evaluated using a weighted kappa score. Each focus of abnormal increased tracer uptake was recorded using a 4-point diagnostic confidence scale. Institutional Review Board approval was obtained. Fifty lesions on planar bone scintigraphy in the 40 patients were evaluated. On reporting the planar study and SPECT scans, reviewers rated 61% of lesions as equivocal. On reporting the SPECT/CT scans only 8% of lesions were rated as equivocal, 24% were rated as malignant and 68% as benign. Weighted kappa scores for inter-reviewer agreement were 0.43 for bone scintigraphy, 0.56 for SPECT and 0.87 for SPECT/CT. All were significant at p < 0.0001. Follow-up imaging confirmed the SPECT/CT diagnoses in 14 patients. The addition of SPECT/CT resulted in a significant reduction of equivocal reports; a definitive diagnosis was given in the majority of the patients due to the improved diagnostic confidence compared to planar or SPECT imaging alone in prostate cancer patients with suspected bone metastases. (orig.)

Helyar, Vincent [King' s College London, School of Medicine, Taunton, Somerset (United Kingdom); Mohan, Hosahalli K.; Barwick, Tara; Livieratos, Lefteris; Gnanasegaran, Gopinath; Clarke, Susan E.M.; Fogelman, Ignac [Guy' s and St Thomas' NHS Foundation Trust, Department of Nuclear Medicine, London (United Kingdom)

2010-04-15

249

MRI in suspicious breast lesions  

International Nuclear Information System (INIS)

Purpose: The value of MRI in the detection and handling of oncologic pathology. Multifocality and multi centricity. Re-evaluation of post-surgical breast. Material and methods: 18 female patients (age ranged between 35-79 years, mean age 52 years) were studied with MRI under suspicion of neoplastic breast lesions. In 16 patients stereotactic automated large core-biopsies as well as surgical biopsies were performed. Results: From the 18 patients studied with MRI, 9 (50%) had palpable lesions, 5 (28%) had no palpable lesions (infra-clinical), and 4 patients (22%) post-surgical changes. 16 patients underwent surgical or core-biopsies, and 2 patients are under a follow up protocol. In 6 patients (33%) with palpable lesions MRI findings correlated well with surgical biopsies. In 2 patients with palpable nodular lesions and pathological enhancement in MRI one had a cancer and the other had a post-surgical fibrosis. In 4 patients with infra clinical lesions, MRI showed multifocal or multi centrical lesions in 3 (16%) and post-surgical changes in 1 (5%). We had 3 false positives: one patient with a palpable nodular lesion, one patient with a non palpable lesion and one case with abnormal area of gadolinium enhancement, that not represented the localization of the tumor at surgery. Conclusion: Substraction dynamic MRI has been able to detect primary occult tumors and multi centricity/multifocality, changing the surgical planning in the management of breast cancer. Post-surgical breast evaluation is always difficult, but in some cases MRI established the presence of local recurrence confirmed by the pathologist after surgical or core-biopsies. (author)

2004-01-01

250

Nerve lesioning with direct current  

Science.gov (United States)

Spastic hypertonus (muscle over-activity due to exaggerated stretch reflexes) often develops in people with stroke, cerebral palsy, multiple sclerosis and spinal cord injury. Lesioning of nerves, e.g. with phenol or botulinum toxin is widely performed to reduce spastic hypertonus. We have explored the use of direct electrical current (DC) to lesion peripheral nerves. In a series of animal experiments, DC reduced muscle force by controlled amounts and the reduction could last several months. We conclude that in some cases controlled DC lesioning may provide an effective alternative to the less controllable molecular treatments available today.

Ravid, E. Natalie; Shi Gan, Liu; Todd, Kathryn; Prochazka, Arthur

2011-02-01

251

FEM Study Cervical Lesions Mechanism  

Directory of Open Access Journals (Sweden)

Full Text Available The causes of dental abfraction used to be a controversial subject. Although mechanical theory gained popularity, the mechanism of formation of cervical lesions is not fully explained. This approach points to the conclusion that the cervical area of the tooth, where this type of lesion usually occurs, concentrates the stress resulted from the action of the forces applied on various areas of the crown. Moreover, any lesion in the cervical area facilitates the possibility of its advance into the tooth, ultimately fracturing it. Our paper presents the mechanical analysis using the finite elements method (FEM of a tooth under two different loads.

Ligia Brezeanu

2010-12-01

252

Indeterminate lesions on planar bone scintigraphy in lung cancer patients: SPECT, CT or SPECT-CT?  

Energy Technology Data Exchange (ETDEWEB)

The objective of the present study was to compare the role of single photon emission computed tomography (SPECT), computed tomography (CT) and SPECT-CT of selected volume in lung cancer patients with indeterminate lesions on planar bone scintigraphy (BS). The data of 50 lung cancer patients (53 {+-} 10.3 years; range 30-75; male/female 38/12) with 65 indeterminate lesions on planar BS (January 2010 to November 2010) were retrospectively evaluated. All of them underwent SPECT-CT of a selected volume. SPECT, CT and SPECT-CT images were independently evaluated by two experienced readers (experience in musculoskeletal imaging, including CT: 5 and 7 years) in separate sessions. A scoring scale of 1 to 5 was used, in which 1 is definitely metastatic, 2 is probably metastatic, 3 is indeterminate, 4 is probably benign and 5 is definitely benign. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated for each modality, taking a score {<=}2 as metastatic. With receiver operating characteristic (ROC) curve analysis, areas under the curve (AUC) were calculated for each modality and compared. Clinical and imaging follow-up and/or histopathology were taken as reference standard. For both readers SPECT was inferior to CT (P = 0.004, P = 0.022) and SPECT-CT (P = 0.003, P = 0.037). However, no significant difference was found between CT and SPECT-CT for reader 1 (P = 0.847) and reader 2 (P = 0.592). The findings were similar for lytic as well as sclerotic lesions. Moderate inter-observer agreement was seen for SPECT images ({kappa} = 0.426), while almost perfect agreement was seen for CT ({kappa} = 0.834) and SPECT-CT ({kappa} = 0.971). CT alone and SPECT-CT are better than SPECT for accurate characterisation of indeterminate lesions on planar BS in lung cancer patients. CT alone is not inferior to SPECT-CT for this purpose and might be preferred because of shorter acquisition time and wider availability. (orig.)

Sharma, Punit; Kumar, Rakesh; Singh, Harmandeep; Bal, Chandrasekhar; Malhotra, Arun [All India Institute of Medical Sciences, Department of Nuclear Medicine, New Delhi (India); Julka, Pramod Kumar [All India Institute of Medical Sciences, Department of Radiation Oncology, New Delhi (India); Thulkar, Sanjay [All India Institute of Medical Sciences, Department of Radiodiagnosis, New Delhi (India)

2012-07-15

253

A new species of Astyanax Baird & Girard (Characiformes: Characidae) from the Rio Paraguaçu basin, Chapada Diamantina, Bahia, Brazil, with comments on bony hooks on all fins.  

Science.gov (United States)

A new species of Astyanax from the Rio Paraguaçu basin, Bahia, Brazil, is described. This new species is distinguished from its congeners known to occur in Brazilian drainages by the presence of small bony hooks on all fins of mature males. Furthermore, the new species can be diagnosed by its colour pattern, which consists of a unique vertically elongated humeral blotch, a conspicuous dark drop-shaped horizontal blotch over the caudal peduncle, tapering anteriorly and not extending to the median caudal-fin rays, and by the absence of a conspicuous broad dark midlateral stripe. The new species differs further by having the greatest body depth just anterior to the dorsal-fin origin, 32-35 perforated scales in the lateral line and a reduced number of branched anal-fin rays (16-20). Apparently, the new species does not fit into any species complex of Astyanax. The occurrence of bony hooks on all fins of Astyanax is discussed. PMID:24446730

Camelier, P; Zanata, A M

2014-02-01

254

Temporary removal of the posterior bony canal wall with reconstruction using microplate osteosynthesis in cholesteatoma surgery: a case series and description of the technique.  

Science.gov (United States)

We describe the surgical technique of temporary removal of the posterior auditory canal wall with reconstruction and report the outcome of using this technique as a treatment method for cholesteatoma in a case series. In 32 cases of cholesteatoma surgery a technique of temporary removal of the posterior bony wall was applied. During primary surgery the posterior auditory canal wall was removed using an oscillating saw. For the purpose of reconstruction, the canal wall was repositioned and fixed using two titanium microplates (n = 26). In case the canal wall could not be reconstructed with osteosynthesis, either glass-ionomeric cement (BioCem™) was used for fixation (n = 4) or fibrin glue (Tissucol™) (n = 2) to support the posterior wall. The outcome includes the healing process in the first postoperative month, the absence of residual or recurrent disease and the successful reconstruction of the posterior auditory canal wall as evaluated during second-look surgery. When microplates where used, we saw healing problems of the canal skin in about 4% of patients. Recurrent cholesteatoma was found in 4 cases (14%), residual cholesteatoma in 8 ears (25%). In the osteosynthesis group, successful reconstruction was achieved in 25 patients (96%). In 3 out of 4 patients of the glass-ionomeric cement group (75%) excessive granulation tissue developed with extensive bony lysis. Temporary removal of the posterior auditory canal wall offers potential for the control of cholesteatoma. Our first results suggest that osteosynthesis allows for a good anatomical and functional reconstruction. PMID:23942812

Van der Gucht, Karen; Van Rompaey, Vincent; Vanderveken, Olivier; Van de Heyning, Paul; Claes, Jos

2014-06-01

255

Traumatic lesions of pulmonary parenchyma  

International Nuclear Information System (INIS)

Five cases of post-traumatic pulmonary lesions (contusion, laceration and hematoma) are presented. The pathophysiology, radiological aspects and differential diagnosis are reviewed. The benign evolution showing the absorption in short time, without medical interference is emphasized. (Author)

1984-01-01

256

Post-radiotherapeutic heart lesions  

International Nuclear Information System (INIS)

Heart structures have traditionally been considered radioresistant. In fact all tissues subjected to radiotherapy can develop lesions. Possible damage includes: - pericardiac fibrosis, the commonest and best individualized, associated with a constriction this leads to a stoppage pattern usually occurring late, around the 18th month. Its frequency depends directly on the total radiation dose; - fibrous myocarditis by direct damage to the heart muscle; - stenosis type lesions of the large coronary trunks; - in exceptional cases lesions of the aorta: hyperplastic degenerescence of the intima and adventitia or of the aortic sigmoid valvules and the mitral valves. Three observations are reported, concerning a coronary, a pericardiac and a coronary, myocardiac and pericardiac lesion. Following this account the irradiation techniques and main experimental data are reviewed and the prophylactic and therapeutic consequences to be derived from our observations and those of the literature are examined

1979-01-01

257

Brain lesions and eating disorders  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Objective: To evaluate the relation between lesions of various brain structures and the development of eating disorders and thus inform the neurobiological research on the aetiology of these mental illnesses.

2005-01-01

258

Ocular lesions in irradiated beagles  

International Nuclear Information System (INIS)

Both Segment II and Segment III dogs exposed at 28 or 55 days postcoitus (dpc) or at 2 days postpartum (dpp), when the retina is still developing, were evaluated clinically and histopathologically for the presence of retinal lesions. The Segment II dogs received 0 to 355 rads and were sacrificed at 70 days or 2 to 4 years of age. The Segment III experimental groups received 0, 16 or 83 rads and were sacrificed at 5 years of age. Findings in the Segment II irradiated dogs included retinal dysplasia and progressive retinal atrophy accompanied by retinal vascular attenuation. The severity and extent of the lesions increased with dose. The localization of the lesions in the retina was dependent on the age at irradiation, hence, the state of differentiation of the developing retina. No clear evidence of radiation-induced retinal lesions was seen in Segment III dogs sacrificed at 5 years of age

1981-01-01

259

Investigation of CT and MRI findings of cranio-orbital communicating lesions  

International Nuclear Information System (INIS)

Objective: To investigate CT and MRI findings of cranio-orbital communicating lesions so as to find out communicating passages and their imaging features. Methods: Fifty-one cases of cranio-orbital communicating lesions confirmed by pathology and follow-up results were studied. CT was performed in all cases and MRI in 45 cases. Post-contrast CT and MRI was completed in 44 cases. Results: There were 31 cases (60.8%) with lesions communicating between the orbital cavity and the cranial cavity through optic canal or superior orbital fissure showing communicating soft tissue mass and enlargement of optic canal or superior orbital fissure. Four cases of optic gliomas involving optic nerve and optic chiasm, three cases with meningiomas of optic nerve sheath, and 2 cases with retinoblastoma involving optic nerve and optic chiasm showed cranio-orbital communicating masses through the optic canal. Cranio-orbital communicating mass with enlargement of superior orbital fissure was found in 22 patients including 5 meningiomas, 4 neurogenic tumors, 1 dermoid cyst, 3 inflammatory pseudotumors, 2 Tolosa-Hunt syndromes and 7 metastases from nasopharyngeal carcinoma. In addition, 20 of 51 cases (39.2%) communicated through perforating blood vessels or bony defect resulted from tumor destruction. Of these lesions, there were 10 metastases showing bone destruction in orbital walls, 5 cases with en plaque meningiomas of sphenoid bone with marked hyperostosis and widespread dural involvement, 1 chondrosarcoma involving frontal lobe and orbit, 3 adenoid cystic carcinomas involving frontal lobe, and 1 malignant meningioma with bone destruction of the superior orbital wall. Conclusion: CT and MRI could definitely demonstrate communicating passages of cranio-orbital communicating lesions and their imaging changes, which could contribute to diagnosis and differential diagnosis and provide valuable information for determining treatment measures and surgical approach

2001-05-01

260

MRI of Focal Liver Lesions  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Magnetic resonance imaging, MRI has more advantages than ultrasound, computed tomography, CT, positron emission tomography, PET, or any other imaging modality in diagnosing focal hepatic masses. With a combination of basic T1 and T2 weighted sequences, diffusion weighted imaging, DWI, and hepatobiliary gadolinium contrast agents, that is gadobenate dimeglumine (Gd-BOPTA) and gadoxetic acid (Gd-EOB), most liver lesions can be adequately diagnosed. Benign lesions, as cyst, hemangioma, focal nod...

Albiin, Nils

2012-01-01

 
 
 
 
261

Mucocutaneous Lesions of Behçet's Disease  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Behçet's disease is particularly prevalent in "Silk Route" populations, but it has a global distribution. The diagnosis of the disease is based on clinical criteria as there is as yet no pathognomonic test, and mucocutaneous lesions, which figure prominently in the presentation and diagnosis, may be considered the diagnostic hallmarks. Among the internationally accepted criteria, painful oral and genital ulcers, cutaneous vasculitic lesions and reactivity of the skin to needle prick ...

2007-01-01

262

MRI atlas of MS lesions  

Energy Technology Data Exchange (ETDEWEB)

MRI has become the main paraclinical test in the diagnosis and management of multiple sclerosis. We have demonstrated more than 400 pictures of different typical and atypical MS lesions in this atlas. Each image has a teaching point. New diagnostic criteria and differential diagnosis are discussed and the book is supported by a teaching DVD where the reader can see MS lesions in different slices and sequences. (orig.)

Sahraian, Mohammad Ali [Tehran Univ. of Medical Sciences Sina Hospital (Iran). Dept. of Neurology; Radue, Ernst-Wilhelm [Univ. Hospital Basel (Switzerland). Dept. of Neuroradiology

2008-07-01

263

MRI atlas of MS lesions  

International Nuclear Information System (INIS)

MRI has become the main paraclinical test in the diagnosis and management of multiple sclerosis. We have demonstrated more than 400 pictures of different typical and atypical MS lesions in this atlas. Each image has a teaching point. New diagnostic criteria and differential diagnosis are discussed and the book is supported by a teaching DVD where the reader can see MS lesions in different slices and sequences. (orig.)

2008-01-01

264

Multiple sclerosis masquerading as a mass lesion  

International Nuclear Information System (INIS)

Six patients presenting with new neurological deficits underwent magnetic resonance imaging (MRI) that displayed mass lesions leading to diagnoses of tumor or abscess. Biopsy revealed demyelinating lesions. (orig.)

1992-04-01

265

Save-a-tooth: Conservative surgical management of dentigerous cyst  

Directory of Open Access Journals (Sweden)

Full Text Available Dentigerous cysts are the most common bony lesions of the jaws in children. It is one of the most prevalent types of odontogenic cysts associated with an erupted or developing tooth, particularly the mandibular third molars; the other teeth that are commonly affected are, in order of frequency, the maxillary canines, the maxillary third molars, and rarely the central incisors. Radiographically, the cyst appears as ovoid well-demarcated unilocular radiolucency with a sclerotic border. Careful evaluation of the history and the clinical and radiographical findings help clinicians to currently diagnose the condition, identify the etiological factors, and administer the appropriate treatment.

Shivaprakash P

2009-03-01

266

Cystic parotid gland lesion evaluation  

International Nuclear Information System (INIS)

We evaluated differential diagnoses of cystic parotid gland lesions and the efficacy of preoperative diagnosis. Of 191 parotid gland nodules resected between January 2003 and October 2008, 167 (87%) were benign and 24 (13%) malignant. Thirty-five parotid gland nodules whose components were almost cystic were enrolled in this study. All cystic lesions were retrospectively evaluated with respect to preoperative diagnostic examinations and histopathological confirmed diagnosis. Cystic components in surgical specimens were also evaluated histopathologically. The relationships with magnetic resonance imaging (MRI) findings and histopathological confirmed diagnosis were studied. Of 35 cystic lesions, 11 were complete cystic masses and had no mural nodules, while remaining 24 were incomplete and had mural nodules. Histopathological examinations showed that 5 were nonneoplastic, 27 were cystic degenerations of benign tumors, and 3 were cystic degenerations of malignant tumors. In the 11 complete cysts, preoperative diagnosis could not be made using any modality, whether with fine needle aspiration cytology (FNAC), salivary scintigraphy, or 67-gallium citrate scintigraphy. Of 24 incomplete cysts, only 9 cystic Warthin tumors were diagnosed correctly before surgery. Studies of cystic components in MRI and histopathology suggested that hemorrhagic degeneration of malignant tumors should be kept in mind for cystic lesions showing hemorrhagic portions. Cystic parotid gland lesions are difficult to diagnose correctly before surgery, but the evaluation of cystic components by MRI and FNAC is helpful in differentiating between benign and malignant tumors. (author)

2010-05-01

267

Focal splenic lesions: US findings.  

Science.gov (United States)

Ultrasound (US) imaging of the spleen was considered of little use in the past and was performed only to distinguish between cystic and solid lesions. However, in the last decade due to experience acquired and the introduction of second-generation contrast agents, this technique has been re-evaluated as contrast-enhanced US (CEUS) allows detection and characterization of most focal lesions of the spleen with a high sensitivity and a good specificity. Gray-scale US presents a low specificity in splenic infarctions with a high rate of false negative cases, whereas specificity reaches 100 %, if the examination is performed using US contrast agents. Gray-scale US can provide a correct diagnosis in simple cysts, whereas CEUS is useful when cystic lymphangioma is suspected. In the study of splenic lesions, the most important problem is to differentiate between angioma, hamartoma, lymphoma, and metastasis. CEUS reaches a good specificity in the differentiation of benign from malignant splenic lesions, as hypo-enhancement in the parenchymal phase is predictive of malignancy in 87 % of cases. In conclusion, Gray-scale US and particularly CEUS are at present widely indicated in the study of focal splenic lesions. PMID:24294345

Caremani, M; Occhini, U; Caremani, A; Tacconi, D; Lapini, L; Accorsi, A; Mazzarelli, C

2013-01-01

268

Brain radiation lesions: MR imaging  

International Nuclear Information System (INIS)

This retrospective study was performed to assess the capability of magnetic resonance (MR) to depict and characterize diffuse and focal radiation lesions in the brain using the spin-echo technique. The MR images of 55 patients who had undergone radiation therapy were reviewed. Comparative computed tomography (CT) studies were available for all the patients. Normal white matter was chosen as reference tissue for the quantitative comparison of signal intensities. Radiation lesions (identified in eight patients) were seen as regions of high signal intensity on the sequence with a long repetition time (TR) (2.0 sec) and showed no difference in signal compared with white matter when the TR was short (0.5 sec). Nonspecific prolongation of T1 and T2 relaxation times was measured in such lesions. In one patient, subependymal tumor spread, demonstrated by contrast-enhanced CT, was missed on MR images, masked by the adjacent abnormal signal owing to radiation effects. Recurrent or residual brain tumor could not be distinguished from radiation brain necrosis either by CT or by MR imaging. It is concluded that MR can depict radiation lesions with great sensitivity but is not very helpful for discrimination between recurrent or residual brain tumor, radiation necrosis, and other brain lesions

1986-01-01

269

Comparação entre hidroxiapatita porosa de coral e enxerto ósseo autógeno em coelhos Comparison between porous hydroxyapatite of chorale and autogenous bony graft in rabbits  

Directory of Open Access Journals (Sweden)

Full Text Available A transplantação de osso autógeno continua sendo usada com sucesso, apesar das limitações que apresenta, principalmente no que se refere à morbidade aumentada, operações adicionais e aumento do custo. O objetivo desta pesquisa foi verificar a integração da hidroxiapatita porosa de coral como alternativa biológica, em forma de cerâmica, para substituir o enxerto ósseo autógeno. Foram utilizados 42 coelhos albinos (Nova Zelândia, submetidos a defeito padrão em 84 côndilos femorais, e implantação aleatória, em cada lado, de enxerto ósseo autógeno ou hidroxiapatita porosa. Foram avaliados os aspectos da evolução clínica diária dos animais. Após duas, quatro e doze semanas, grupos de 14 animais foram sacrificados e feita a avaliação radiológica e macroscópica da integração dos enxertos. Peças das regiões operadas foram colhidas para estudo histológico dessa integração. Os resultados macroscópicos mostraram que a integridade óssea, coloração, cicatrização da cortical e mobilidade dos implantes não foram estatisticamente significantes para os dois tipos de enxertos, nos diferentes tempos de observação. A diferença de uma progressiva e melhor integração dos enxertos ocorreu apenas quando se compararam os três tempos de observação, e foi considerada como conseqüência direta da evolução natural do processo cicatricial. Os parâmetros radiológicos de integração seguiram o mesmo padrão dos achados macroscópicos. Os achados microscópicos mostraram que o aparecimento de tecido ósseo maduro é retardado nos enxertos de hidroxiapatita com a ocorrência de cavidades císticas. Concluiu-se que a hidroxiapatita porosa de coral foi um substituto adequado ao enxerto ósseo autógeno em coelhos.The transplantation of autogenous bone continues being used with success, in spite of the disadvantages that it presents, mainly in what refers the increased morbidity, additional operations and increase of the cost. The objective of this research was to verify the integration of the porous hydroxyapatite of chorale as biological alternative in ceramic form to substitute the autogenous bony graft. Forty-two New Zealand rabbits were submitted to na standard condylar defect witch were randomic implanted by autogenous bony graft as porous hydroxyapatite of chorale. We made clinical, macroscopic, radiographic and histologic study among the time of evolution of two, four and twelve weeks, respectively. The results were similar between the autogenous graft and the porous hydroxyapatite of chorale in the evolution of twelve weeks. It was ended that the porous hydroxyapatite of chorale is a substitute adapted to the autogenous bony graft in rabbits.

Arthur Silveira de Figueiredo

2001-09-01

270

Use of enamel matrix protein derivative with minimally invasive surgical approach in intra-bony periodontal defects: clinical and patient-centered outcomes  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in portuguese O objetivo deste estudo foi avaliar os resultados clínicos e centrados no paciente após abordagem cirúrgica minimamente invasiva (CMI) associada à aplicação das proteínas derivadas da matriz do esmalte (PDE) no tratamento de defeitos infra-ósseos. Doze pacientes apresentando um sítio com profundidad [...] e de sondagem >5 mm e sangramento à sondagem , associado à evidência radiográfica de defeito infra-ósseo, foram tratados com CMI e aplicação das PDE. Os parâmetros clínicos foram avaliados imediatamente antes do procedimento e após 3 e 6 meses. A percepção de dor e desconforto do paciente durante o período trans-cirúrgico e ao longo da primeira semana de pós-operatório, bem como a satisfação estética 6 meses após o tratamento, foram avaliadas por meio de questionários. Os resultados mostraram que o uso da CMI associada à aplicação de PDE promoveu melhoras estatisticamente significantes nos parâmetros clínicos, mínima dor e desconforto e máxima satisfação estética aos pacientes. Dentro dos limites do estudo, foi demonstrado que a associação de CMI e PDE, no tratamento de defeitos infra-ósseos, é capaz de promover satisfatórios resultados clínicos e centrados no paciente. Abstract in english This case series evaluated the clinical performance and patient-centered outcomes after a minimally invasive surgical technique (MIST) associated with enamel matrix protein derivative (EMD), for the treatment of intra-bony defects. Twelve patients presenting teeth with probing depth >5 mm and bleedi [...] ng on probing associated with radiographic evidence of intra-bony defect were treated by MIST associated with EMD. Clinical parameters were measured at baseline, 3 and 6 months. Patient perception during the intraoperative period and during the first postoperative week was evaluated. The use of MIST with EDM promoted significant improvements in clinical parameters, minimal pain/discomfort and maximum esthetics satisfaction. Within of limits of the present study, it could be shown that MIST combined with EMD for the treatment of intra-bony defects promotes satisfactory clinical and patient-centered outcomes.

Fernanda Vieira, Ribeiro; Francisco Humberto, Nociti Júnior; Enilson Antonio, Sallum; Antonio Wilson, Sallum; Márcio Zaffalon, Casati.

271

Lesiones focales hepáticas en niños / Focal liver lesions in children  

Scientific Electronic Library Online (English)

Full Text Available SciELO Venezuela | Language: Spanish Abstract in spanish Introducción: Las lesiones focales del hígado comprenden un grupo heterogéneo de entidades como tumores benignos y malignos, sólidos o quistes, vasculares, masas inflamatorias y metástasis, entre otras. Objetivo: reportar lesiones focales hepáticas en niños, características clínicas, estudios por im [...] ágenes y conducta terapéutica. Pacientes y Métodos: Estudio descriptivo, retrospectivo, basado en la revisión de 16 historias clínicas de niños con lesiones focales hepáticas en el periodo comprendido entre enero 2007 a enero 2012. Se excluyeron los abscesos hepáticos. Resultados: El 68,75%11 eran del sexo masculino y 31,25%5 del sexo femenino; con edad promedio de 9,5 años (rango: 10 días - 14 años). Las lesiones focales benignas fueron: hemangioma 4/16 (25%), hematoma hepático 4/16 (25%), quiste hepático 3/16 (18,75%), hiperplasia nodular focal 1/16 (6,25%) adenoma 1/16 (6,25%) y las malignas: hepatocarcinoma 2/16 (12,50%) y hepatoblastoma 1/16 (6,25%). La mayoría de los pacientes (56,25%) se encontraban asintomáticos, 3/16 (18,75%) presentaron dolor abdominal, 3/16 (18,75%) masa palpable y 2/16 (12,5%) ictericia. La lesión fue identificada por ultrasonido abdominal en todos los pacientes y sólo el 56,25% (9/16) ameritaron tomografía con contraste. Al 43,75% (7/16) se les realizó marcadores tumorales y de estos el 42,85% (3/7) reportaron neoplasias. El funcionalismo hepático reportó normal en el 75% de los casos. Conclusión: El ultrasonido abdominal es el método de elección para el diagnóstico y seguimiento de las lesiones focales hepáticas, mientras el origen de las mismas, guía la conducta terapéutica. Abstract in english Introduction: focal liver lesions comprise a heterogeneous group of entities such as benign and malignant, solid or cysts, vascular, inflammatory masses and metastasis among others. Objective: To report focal liver lesions in children, clinical features, imaging and therapeutic behavior. Patients an [...] d Methods: A descriptive, retrospective study based on a review of 16 case histories of children with focal liver lesions in the period from January 2007 to January 2012. Liver abscesses were excluded. Results: 68.75%11 were male and 31.25%5 females, mean age 9.5 years (range: 10 days - 14 years). Focal lesions were benign: Hemangioma 4/16 (25%), liver hematoma 4/16 (25%), hepatic cyst 3/16 (18.75%), nodular focal hyperplasia 1/16 (6.25%) and adenomas 1/16 (6.25%) and malignant: Hepatocellular carcinoma 2/16 (12.50%) and hepatoblastoma 1/16 (6.25%). Most patients (56.25%) were asymptomatic, 3/16 (18.75%) had abdominal pain, 3/16 (18.75%) and palpable mass 2/16 (12.5%) jaundice. The lesion was identified by abdominal ultrasound in all patients and only 56.25% (9/16) needed tomography with contrast. To 43.75% (7/16) underwent tumor markers and of these 42.85% (3/7) reported neoplasm. Normal hepatic function reported in 75% of cases. Conclusion: An abdominal ultrasound is the method of choice for the diagnosis and management of focal liver lesions, while the origin of them, guide therapeutic conduct.

Rossell, Adalis; Navarro, Dianora; López, Karolina; Perla, Enicar; Quintana, Betzabeth; Figueredo, Credy; Nogales, Andrea; Belandria, Katiuska.

272

Imaging of extradural spinal lesions; Bildgebung extraduraler Raumforderungen  

Energy Technology Data Exchange (ETDEWEB)

There is a wide variety of spinal extradural tumors. In addition to real neoplasms, degenerative diseases, congenital abnormalities and inflammatory disorders can be causes of extradural masses. Due to the bony boundary of the spinal canal, both benign as well as malignant masses can cause progressive neurological deficits including paraplegia. Most of the spinal tumors are benign (hemangioma of the vertebral body, degenerative diseases). In younger patients congenital abnormalities and primary tumors of the spine have to be considered, whereas in adults the list of differential diagnoses should include secondary malignancies such as metastases and lymphomas as well as metabolic disorders such as osteoporotic vertebral compression fracture and Paget's disease. Cross-sectional imaging techniques such as magnetic resonance imaging (MRI) and computed tomography (CT) of the spine often help to make a specific diagnosis of extradural spinal lesions and represent important tools for tumor staging and preoperative evaluation. (orig.) Das Spektrum der spinalen extraduralen Tumoren ist sehr gross. Neben echten Neoplasien koennen auch degenerative Veraenderungen und Anlagestoerungen sowie entzuendliche Veraenderungen Ursachen einer extraduralen Raumforderung sein. Aufgrund der knoechernen Begrenzung des Spinalkanals koennen neben Malignomen auch benigne Tumoren und degenerative spinale Veraenderungen zu progredienten neurologischen Ausfallsymptomen (einschliesslich Querschnittsymptomatik) fuehren. Die ueberwiegende Mehrzahl der extraduralen Raumforderungen der Wirbelsaeule ist benigne (Haemangiom des Wirbelkoerpers, degenerative Erkrankungen). Bei jungen Patienten sind Anlagestoerungen und primaere Wirbelsaeulentumoren zu beruecksichtigen, wogegen beim Erwachsenen an sekundaere Malignome, wie Metastasen und Lymphome sowie eine metabolische Erkrankung, wie die osteoporotische Wirbelkoerpersinterungsfraktur oder der Morbus Paget, differenzialdiagnostisch gedacht werden sollte. Schnittbilddiagnostische Verfahren, wie die Computertomographie und die Magnetresonanztomographie, der Wirbelsaeule ermoeglichen in vielen Faellen eine artdiagnostische Zuordnung von Wirbelsaeulenlaesionen und sind ein wichtiges Instrument fuer das Tumorstaging und die praeoperative Planung. (orig.)

Ahlhelm, F.; Schulte-Altedorneburg, G.; Naumann, N.; Reith, W. (Universitaetsklinikum des Saarlandes, Klinik fuer Diagnostische und Interventionelle Neuroradiologie, Homburg/Saar); Nabhan, A. (Universitaetsklinikum des Saarlandes, Homburg/Saar, Klinik fuer Allgemeine und Spezielle Neurochirurgie)

2006-12-15

273

Ewing's sarcoma. Radiographic pattern of healing and bony complications in patients with long-term survival  

Energy Technology Data Exchange (ETDEWEB)

The radiographic appearance of Ewing's sarcoma was studied retrospectively in 22 patients who survived 5 years or longer after diagnosis and treatment. Expected changes from treatment, including regression of the extraosseous soft tissue mass, periostitis, and reconstitution of the cortex, occurred in all patients. Local recurrence occurred in one patient 10 years after complete remission whereas secondary osteosarcoma occurred more than 5 years after complete remission in two other cases. Both recurrent and secondary tumors presented as new lytic foci at the site of the original primary lesion. Lytic changes from radiation (radiation osteitis) may develop more than 2 years after treatment and in this sample; such findings were widely distributed in the radiation port. The authors conclude that bone remodeling and postradiation changes occur slowly over 2 years after treatment, and that any localized lysis at the primary site is suspicious for recurrence or secondary neoplasm. Knowledge of the expected changes and patterns of local recurrence and secondary neoplasms helps one to detect any significant change in its early phase.

Ehara, S.; Kattapuram, S.V.; Egglin, T.K. (Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston (United States))

1991-10-01

274

Dual lesions: a diagnostic dilemma.  

Science.gov (United States)

Glandular odontogenic cyst (GOC) is a rare aggressive developmental cyst of the jaw. It most commonly occurs in middle-aged people with mandible anterior region being the most affected site. This lesion can present as a unilocular or multilocular radiolucency and has high recurrence rate. The histopathologic features of the GOC are complex and often coincide with the features of dentigerous cyst, radicular cyst, and low-grade central mucoepidermoid carcinoma (CMEC). At times, the microscopic features are so similar to central low-grade mucoepidermoid carcinoma that it becomes highly impossible to distinguish the two entities even with various advanced investigations. The reported case represents one such diagnostic dilemma occurring in the maxilla which is a rare site, and the lesion/s appeared as two distinct entities, that is, GOC and CMEC on either aspects of the same side of maxilla clinically, yet showing continuity on advanced imaging and demonstrating histopathological perplexity. PMID:23970979

Prabhat, M P V; Deshpande, Prasannasrinivas; Gummadapu, Sarat; Babburi, Suresh; Chintamaneni, Raja Lakshmi; Sujanamulk, Bhavana

2013-01-01

275

'Cold lesions' in bone scintigraphy  

International Nuclear Information System (INIS)

Frequency and location of 'cold lesions' has been analysed in 1000 consecutive bone scans. Among the 554 abnormal cases there were 18 (1,8% of the total) with localized diminished activity due to metastatic lesions and 5 (0,5%) secondary to radiation osteitis. 10 of the 18 patients with metastatic disease had pure defects while 8 showed a reactive margin. It is pointed out that the quality of the examination is crucial for the demonstration of such defects and that single scans of the different regions of the skeleton are superior to a whole body scan. The survey of the literature shows that 'cold lesions' are predominant in malignant bone diseases, however no relation exists to a definite histology. (orig.)

1979-01-01

276

Renal lesions of nondomestic felids.  

Science.gov (United States)

To comprehensively evaluate the occurrence of renal lesions in a variety of nondomestic felids, necropsy cases from 1978 to 2008 were reviewed from a municipal zoo and a large cat sanctuary for those in which the kidneys were examined histologically. Seventy exotic felids were identified (25 tigers, 18 lions, 6 cougars, 5 leopards, 3 snow leopards, 3 clouded leopards, 3 Canadian lynx, 2 ocelots, 2 bobcats, 2 cheetahs, 1 jaguar), and their histologic renal lesions were evaluated and compared. The most common lesion was tubulointerstitial nephritis (TIN); 36 of 70 (51%) cats were affected to some degree. Lymphocytic interstitial nephritis was the most common lesion in the tigers (9 of 25, 36%) and was rarely seen in other species. Although the renal pelvis was not available for all cats, 28 of 47 (60%) had some degree of lymphocytic pyelitis. There was no significant association between the presence of pyelitis and that of TIN. Only 1 cat had pyelonephritis. Renal papillary necrosis was present in 13 of 70 (19%) cats and was significantly associated with historical nonsteroidal anti-inflammatory drug treatment (odds ratio, 7.1; 95% confidence interval, 1.9 to 26.8). Only 1 cat (lion) had amyloid accumulation, and it was restricted to the corticomedullary junction. Primary glomerular lesions were absent in all cats. Intraepithelial pigment was identified in many of the cats but was not correlated with severity of TIN. Despite several previous reports describing primary glomerular disease or renal amyloidosis in exotic felids, these lesions were rare to absent in this population. PMID:20876911

Newkirk, K M; Newman, S J; White, L A; Rohrbach, B W; Ramsay, E C

2011-05-01

277

Lesions of juxtacortical origin (surface lesions of bone)  

International Nuclear Information System (INIS)

A large variety of tumor and tumor-like conditions have been shown to originate from the surface of bone. Most surface lesions are associated with periosteal reaction. The periosteum is a multipotential membrane. Its cellular composition may give rise to a variety of both neoplasms and tumor-like conditions. To avoid misinterpretation, the orthopedist, radiologist, and pathologist should be familiar with the entire spectrum of surface lesions. A better understanding of the natural history and biological behavior at different lesional maturity stages and correlation of the history with the radiographic and pathological findings is essential to establish the correct diagnosis. A history of injury of blunt trauma is very important. A stress fracture may produce a periosteal reaction acd callus that can be difficult to distinguish from osteosarcoma. In this review article, the authors wish to describe and define each term by its anatomy and radiographic features while discussing the entire spectrum of surface lesions. All the illustrative cases in this review article have been proven histologically. (orig.)

1993-01-01

278

Localized lesions in secondary syphillis  

International Nuclear Information System (INIS)

The clinical manifestations of secondary syphilis are variable and can mimic many skin diseases, mostly being generalized and symmetrical in distribution. Localized lesions of secondary syphilis are rarely seen in dermatology clinics. We report an unusual presentation wherein a patient had localized lesions over face and soles only. There is a need for increased awareness on the part of physicians to recognize new patterns of syphilitic infection, together with a willingness to consider the diagnosis of syphilis in patients with unusual clinical features. (author)

2008-05-01

279

Small lesion visualization in scintimammography  

International Nuclear Information System (INIS)

For scintimammography (SMM) to have wide clinical use, physicians must be able to rapidly direct biopsy of small cancers. We therefore undertook a theoretical and experimental study of lesion visibility vs. acquisition time and tumor size. Theoretical considerations as to acquisition time and contrast suggested that compression would significantly improve lesion visibility for small cancers. These predictions were confirmed with phantom studies. Patient studies showed that high confidence images of small primary breast tumors can be produced with the addition of breast compression. We conclude that breast compression would improve SMM detection of small primary breast cancers

1996-11-02

280

Effect of decompression surgery on neurological recovery after cervical cord injury with canal stenosis but without distinct bony damage. Multicenter prospective randomized clinical trial  

International Nuclear Information System (INIS)

A prospective randomized clinical trial examining the effects of decompression surgery on neurological recovery in patients with cervical cord injuries without remarkable bony damages was performed at 11 hospitals nationwide in Japan. Cases admitted within 14 days of injury, with a Frankel B or C classification, and with ?20% compression of the spinal cord at the injured level, as seen on MRI, were enrolled. Decompression surgery was selected for cases in which the day of injury was an odd number, while conservative treatment was selected for all other cases. The Frankel classification and ASIA motor scores were followed for one year after injury. No statistically significant differences in neurological recovery were observed between the surgery group and the conservative treatment group. (author)

2006-04-01

 
 
 
 
281

CT-based size and shape determination of the craniofacial skeleton: a new scoring system to assess bony deformities in hemifacial microsomia.  

Science.gov (United States)

The purpose of this study was to design a better craniofacial classification system for bony deformities in patients with hemifacial microsomia than the existing ones. It was meant to incorporate the deformity of the craniofacial skeleton other than that of the mandible. The "Mandibular Deformity Scoring" System (MDS), the "Cranial Deformity Scoring" System (CDS), the the "Craniofacial Deformity Scoring" System (CFDS) are three newly developed classification systems, which are based on three-dimensional computed tomography (3-D CT) reconstructions. The size and shape of the craniofacial structures of 34 children, 25 with hemifacial microsomia and 9 with minimal dysplasia or trauma, were determined from CT scans, using 3-D image segmentation and rendering. Contiguous 1.5-mm CT scans were made using a Philips Tomoscan 350 and were processed using a Cemax 1500X 3-D workstation. The precision of the 3-D imaging was assessed by repeated determinations carried out by two observers (intra- and interreliability). Accuracy of the bone determination technique was assessed by comparing the interpretations of the craniofacial skeleton by 3-D CT reconstructions of laser-stereolithographic 3-D models. Correlations of the Pruzansky/Kaban classification system and the newly developed classification systems were demonstrated by the use of the Pearson product moment correlation coefficients. The new CFDS (= CDS + MDS) provides an adequate basis for assessment of bony structures using three-dimensional imaging and demonstrates a high correlation with the known Pruzansky/Kaban classification system. This new scoring system can handle the wide variety of individual variation of the deformity seen in patients with hemifacial microsomia better than the existing scoring systems. PMID:11314195

Huisinga-Fischer, C E; Zonneveld, F W; Vaandrager, J M; Prahl-Andersen, B

2001-01-01

282

Imaging inflammatory acne: lesion detection and tracking  

Science.gov (United States)

It is known that effectiveness of acne treatment increases when the lesions are detected earlier, before they could progress into mature wound-like lesions, which lead to scarring and discoloration. However, little is known about the evolution of acne from early signs until after the lesion heals. In this work we computationally characterize the evolution of inflammatory acne lesions, based on analyzing cross-polarized images that document acne-prone facial skin over time. Taking skin images over time, and being able to follow skin features in these images present serious challenges, due to change in the appearance of skin, difficulty in repositioning the subject, involuntary movement such as breathing. A computational technique for automatic detection of lesions by separating the background normal skin from the acne lesions, based on fitting Gaussian distributions to the intensity histograms, is presented. In order to track and quantify the evolution of lesions, in terms of the degree of progress or regress, we designed a study to capture facial skin images from an acne-prone young individual, followed over the course of 3 different time points. Based on the behavior of the lesions between two consecutive time points, the automatically detected lesions are classified in four categories: new lesions, resolved lesions (i.e. lesions that disappear completely), lesions that are progressing, and lesions that are regressing (i.e. lesions in the process of healing). The classification our methods achieve correlates well with visual inspection of a trained human grader.

Cula, Gabriela O.; Bargo, Paulo R.; Kollias, Nikiforos

2010-02-01

283

Secondary syphilis lesions resembling pityriasis  

International Nuclear Information System (INIS)

This case report describes a male patient who presented with generalized, centrally-ulcerated papules with crusts and hypopigmented macules. Initially, differential diagnostic considerations included pityriasis lichenoides but the serology for syphilis was positive and there was a rapid response to penicillin with clearing of the lesions at the end of three weeks treatment. (author)

2007-11-01

284

Direct surgery for brainstem lesions  

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Direct surgery for intrinsic lesions of the brainstem has been considered a hazardous procedure. During the past 10 years, 32 cases of symptomatic lesions involving the brainstem were operated on. Magnetic resonance (MR) imaging is of greatest value in the diagnosis and for surgical indications. Almost all cases were treated by radical extirpation. Namely, 9 cavernous angiomas and 2 hemangioblastomas resulted in radical extirpation. The preoperative neurological deficits improved after surgery. Also, 2 ependymomas, 4 medulloblastomas, 4 plexus papillomas, and 1 epidermoid were successfully extirpated, and the surgical treatment for them allowed favorable outcome. Therefore, those brainstem lesions were considered to be more favorable indications for direct surgery. On the other hand, 4 astrocytomas and 6 glioblastomas were either subtotally or partially resected, in which a small incision in the fourth ventricle floor and the surface of the brainstem was made when the lesion was intramedullary. Consequently, there were neither mortality in surgery nor aggravation of the focal neurological symptoms. High-grade glioma in 6 cases was removed as much as possible, but almost all of the cases nevertheless expired due to prompt recurrence under 2 years after onset of symptoms and surgery. (author)

Sakai, Noboru [Gifu Univ. (Japan). School of Medicine

1997-09-01

285

Stereotactic lesioning for mental illness  

International Nuclear Information System (INIS)

The authors report stereotactically created lesioning by radiofrequency or Cyberknife radiosurgery for patients with mental illness. Since 1993, thirty-eight patients have undergone stereotactic psychosurgery for medically intractable mental illnesses. Two patients had aggressive behavior. Twenty-five patients suffered from Obsessive-Compulsive Disorder (OCD) and ten patients had depression. Another patient suffered from atypical psychosis. Bilateral amygdalotomy and subcaudate tractotomy were done for aggressive behavior. Limbic leucotomy or anterior cingulotomy was done for CCD and subcaudate tractotomy with or without cingulotomy was done for depression. In twenty-three patients, the lesions were made by a radiofrequency (RF) lesion generator. In fifteen cases, the lesions were made with Cyberknife Radiosurgery (CKRS). The Overt Aggression Scale (OAS) declined from 8 to 2 with clinical improvement during follow up period. With long-term follow up (meaning 57 months) in 25 OCDs, the mean Yale Brown Obsessive Compulsive Score (YBOCS) declined from 34 to 13 (n = 25). The Hamilton Depression scale (HAMD) for ten patients with depression declined from 38.5 to 10.5 (n = 10). There was no operative mortality and no significant morbidity except one case with transient urinary incontinence. Authors suggest that stereotactic psychosurgery by RF and CKRS could be a safe and effective means of treating some medically intractable mental illnesses. (author)

2008-01-01

286

Lesiones polipoides en intestino delgado  

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Full Text Available Varón  de 50 años  con antecedentes de exposición al asbesto, fumador, bebedor, e historia de tuberculosis en su juventud. Ingresa por derrame pleural derecho sin evidencia de masa pulmonar. Muestra una placa pleural anterior y engrosamiento pleural posterior. En la autopsia se observan lesiones polipoides en la mucosa de todo el intestino delgado.

Sandra Hermana

2013-05-01

287

Odontogenic lesions in pediatric patients.  

Science.gov (United States)

The purpose was to evaluate our 20-year experience of pediatric odontogenic lesions. Pediatric patients with a diagnosis of odontogenic lesion were identified. Three hundred ten patients were odontogenic; dentigerous cyst was seen in 62.0% of the cases. Most (70.2%) of them occurred in mixed dentition period, and it had a male preponderance. Odontogenic keratocystic tumor occurred in the permanent dentition period. It had an equal site distribution. Odontoma was seen in 20.0% of the cases. Its site of predilection was the mandible. Ameloblastoma was the most common odontogenic tumor. Most of the cases occurred in the permanent dentition period. It affected the male and female equally. Calcifying epithelioma odontogenic tumor was seen in 11.8% of the cases. All the lesions occurred in the primary dentition period. It had no sex or site preponderance. Myxoma was seen in 3.6% of the cases. It was most common in the permanent dentition period, and it was more frequent in the male. Iliac crest bone graft was successfully performed in 28 patients, postoperative infection occurred in 2 patients, and no donor-site dysfunctions were reported. The observed differences in lesion type and distribution in this study compared with previous researches may be attributable to genetic and geographic variation in the populations studied. Iliac crest bone graft was suggested for pediatric mandible reconstruction. PMID:24785745

Fang, Qi-Gen; Shi, Shuang; Sun, Chang-Fu

2014-05-01

288

Focal lesions of the patella  

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Focal lesions of the patella may be identified during the investigation of anterior knee pain or as an incidental finding on radiological images. This pictorial review describes the radiographic appearances of a wide range of conditions that have been seen in this sesamoid bone. Where appropriate, computed tomography and magnetic resonance features have been included. (orig.)

Hedayati, B. [Royal national Orthopaedic Hospital Stanmore, Brockley Hill Stanmore, Department of Radiology, Middlesex (United Kingdom); Lewisham Hospital NHS Trust, Department of Radiology, London (United Kingdom); Saifuddin, A. [Royal national Orthopaedic Hospital Stanmore, Brockley Hill Stanmore, Department of Radiology, Middlesex (United Kingdom)

2009-08-15

289

[Review of precancerous vulvar lesions].  

Science.gov (United States)

Classification of squamous vulvar precancerous lesions is based on the concept of vulvar intraepithelial neoplasia (VIN) and incorporates a three grade evaluation of the intensity of dysplastic changes (VIN I, II and III). On the basis of histological features, VIN has been subdivided into the usual VIN (u-VIN) and differentiated VIN (d-VIN), which represent the two basic pathways of the pathogenesis of vulvar squamous cell carcinoma. Although u-VIN is etiologically associated with the human papillomavirus (HPV) infection and histologically corresponds to cervical intraepithelial neoplasia, d-VIN represents the HPV-negative sequence of vulvar carcinogenesis, which is linked to lichen sclerosus (LS) and lichen simplex chronicus (LSC). u-VIN preferentially occurs in relatively young women with a history of cervical, vaginal or vulvar premalignant lesions. On the other hand, d-VIN usually affects postmenopausal women without anamnestic data of other dysplastic lesions of the lower female genital tract. d-VIN is characterized by a higher tendency of stromal invasion than u-VIN and its malignant potential is analogous to carcinoma in situ (VIN III). The histological appearance of d-VIN is subtle with basal atypia and a well-preserved differentiation of the superficial parts of the squamous epithelium, therefore it is frequently misdiagnosed for u-VIN I, LS or LSC in vulvar biopsies. Primarily because of the low diagnostic reproducibility of the u-VIN I category and the doubts about its precancerous potential as well as due to the questionable differentiation between u-VIN II and III, a revised VIN classification was proposed in 2004. The grading of vulvar precancerous lesions was abandoned, the u-VIN I category was discontinued and u-VIN II and III were merged. In the revised terminology, the term u-VIN represents HPV-associated high grade precancerous vulvar lesions (formerly u-VIN II and III) and d-VIN encompasses HPV-negative high grade dysplasias. PMID:22716003

Skapa, P; Robová, H; Rob, L; Záme?ník, J

2012-01-01

290

Petrous apex lesions in the pediatric population  

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A variety of abnormal imaging findings of the petrous apex are encountered in children. Many petrous apex lesions are identified incidentally while images of the brain or head and neck are being obtained for indications unrelated to the temporal bone. Differential considerations of petrous apex lesions in children include ''leave me alone'' lesions, infectious or inflammatory lesions, fibro-osseous lesions, neoplasms and neoplasm-like lesions, as well as a few rare miscellaneous conditions. Some lesions are similar to those encountered in adults, and some are unique to children. Langerhans cell histiocytosis (LCH) and primary and metastatic pediatric malignancies such as neuroblastoma, rhabomyosarcoma and Ewing sarcoma are more likely to be encountered in children. Lesions such as petrous apex cholesterol granuloma, cholesteatoma and chondrosarcoma are more common in adults and are rarely a diagnostic consideration in children. We present a comprehensive pictorial review of CT and MRI appearances of pediatric petrous apex lesions. (orig.)

Radhakrishnan, Rupa [University of Cincinnati College of Medicine, Department of Radiology, Cincinnati, OH (United States); Cincinnati Children' s Hospital Medical Center, Department of Radiology, Cincinnati, OH (United States); Son, Hwa Jung [University of Cincinnati College of Medicine, Department of Otolaryngology-Head and Neck Surgery, Cincinnati, OH (United States); Koch, Bernadette L. [Cincinnati Children' s Hospital Medical Center, Department of Radiology, Cincinnati, OH (United States)

2014-03-15

291

Imaging of Chest Wall Lesions in Children  

Directory of Open Access Journals (Sweden)

Full Text Available Chest wall lesions in childhood include a wide range of pathologies; Benign lesions include lipoma, neurofibroma, lymphangioma, hemangioma, and mesenchymal hamartoma."nMalignant lesions include Neuroblastoma, Rhabdo-myosarcoma, Ewing sarcoma, and Askin tumor."nSystemic diseases such as leukemia, lymphoma, Langerhans cell histiocytosis, and also infections such as tuberculosis, and actinomycosis may also cause chest wall lesions."nThe imaging characteristics of these lesions are re-viewed, but only a minority of the lesions shows diagnostic imaging features, and most of lesions re-quire biopsy and histopathological examination for "ndefinitive diagnosis."nThe role of different modalities is discussed with an emphasis on magnetic resonance imaging for demonstrating lesion morphology and local spread. Computed tomography and neuclear medicine being used mainly to assess remote disease."nIn this lecture, we discuss about imaging of chest wall lesions in children.

A. Hekmatnia

2008-01-01

292

Ossicular chain lesions in cholesteatoma  

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The aim of the study was to describe ossicle resorption in chronic otitis with cholesteatoma and correlate it with clinical parameters such as age, contralateral ear condition, tympanic membrane aspect, cholesteatoma pathogenesis and extension, associated lesions and hearing threshold. Preoperative clinical data were collected for 140 patients with chronic otitis with cholesteatoma, whose ossicles were evaluated during surgery. 82% of patients showed ossicle resorption, with incus damage in 7...

Albera, R.; Canale, A.; Piumetto, E.; Lacilla, M.; Dagna, F.

2012-01-01

293

Precursor Lesions of Pancreatic Cancer  

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This review article describes morphological aspects, gene abnormalities, and mucin expression profiles in precursor lesions such as pancreatic intraepithelial neoplasia (PanIN), intraductal papillary mucinous neoplasm (IPMN), and mucinous cystic neoplasm (MCN) of the pancreas, as well as their relation to pancreatic ductal adenocarcinoma (PDAC). The gene abnormalities in precursors of PDAC are summarized as follows: (1) KRAS mutation and p16/CDKN2A inactivation are early events whose frequenc...

Yonezawa, Suguru; Higashi, Michiyo; Yamada, Norishige; Goto, Masamichi

2008-01-01

294

Endothelial Lesions. Demonstration by Scintiscanning  

International Nuclear Information System (INIS)

Collections of tracer accumulations have been noted by the authors as well as by others in the axillary regions on certain patients who have undergone pulmonary scanning. Reviewing these cases it was noted that a common denominator existed. The patients had been, almost without exception, subjected to venous catheterization with the purpose of administering intravenous fluids. A catheter had been inserted and remained in place for a variable length of time. In some cases accumulation of tracer was seen in the axillary region for on repeat lung scans several weeks after the removal of the catheter. An experimental method was developed in which focal vascular lesions were created within the vascular system. The method consisted of the use of an electrocautery electrode at the end of an intravascular catheter. Electrocautery was applied to the wall of the vessel under fluoroscopic control. After creation of the lesions, tracer doses of various substances including radiotechnetium-labelled albumin macroaggregates were introduced intravascularly. Scintiscanning techniques were used to permit visualization of the distribution of tracer. This paper discusses the distribution of tracer following the production of intravenous and intra-arterial lesions. It is expected that this technique may be applied to many situations in which the vascular endothelium is damaged. Possible applications include demonstration of vascular disease, such as thrombophlebitis, localized vasculitis and arteriosclerotic ulceration. (author)

1969-05-01

295

Radiological diagnosis of adrenal lesions  

International Nuclear Information System (INIS)

Among all the radiological examination techniques, CT is today, besides scintigraphy, the method of choice as far as the detection of functional adrenal lesions is concerned. In primary aldosteronism, CT classification of the syndrome is based on the detection of an adenoma which can be reliably detected in adenoma sizes up to 8-10 mm. Thus, 70 to 80% of Conn's syndromes can be classified. In adrenal Cushing's syndrome, the distinction between adenoma and carcinoma of the adrenal gland is up to CT and can usually be easily made due to the characteristic morphology of each type of lesion. In case of a typcial adrenal or juxtaadrenal tumor location, detection of a pheochromocytoma is likewise easy. In ectopic and multiple pheochromocytomas or such as occur as part of a MEN-syndrome, the situation is quite different. If lesions of the adrenal gland are found by accident in examinations otherwise indicated, the question arises whether the process is malignant or benign. In this respect, all the traditional imaging methods, including CT, involve a considerable factor or uncertainity, especially if a malignant tumor is anamnestically known and the question of metastases arises. According to recent information, MR-imaging seems to be advantageous concerning this difficult differential diagnosis. (orig.)

1986-01-01

296

Surgical treatment of gallbladder polypoid lesions  

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INTRODUCTION Polypoid lesions of the gallbladder can be divided into benign and malignant categories. Malignant polypoid lesions include carcinomas of the gallbladder, which is the fifth most common malignancy of the gastrointestinal tract and the most common malignancy of the biliary tract. Benign polypoid lesions of the gallbladder are divided into true tumors and pseudotumors. Pseudotumors account for most of polypoid lesions of the gallbladder, and include polyps, hyperplasia, and other m...

Peji? Miljko A.; Mili? Dragan J.

2003-01-01

297

CT diagnosis in the otorhinolaryngologic lesions  

International Nuclear Information System (INIS)

Computer tomography (CT) was used in the evaluation of otorhinolaryngologic lesions. CT was capable in imaging of profile of lesion characteristics. Extension of the lesions especially to soft tissue, orbit and pterygopalatine fossa, was well demonstrated. CT provided helpful preoperative information of the lesions especially in the cranium and paranasal sinuses. As a noninvasive diagnostic modality, CT can be usefully included in a battery study of otorhinolaryngologic diseases. (author)

1980-04-01

298

Vertebral lesions associated with palmoplantar pustulosis  

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Spinal lesions were reviewed in 9 patients (3 men and 6 women) who presented with palmoplantar pustulosis. Cervical lesions were found in 3 patients and lumbosacral involvement in 7. The duration of disease averaged 4.8 years. Seven patients had associated sterno-costo-clavicular hyperostotic lesions, and all showed abnormalities in blood tests which suggested chronic inflammation. Vertebral lesions were assessed as a spondylodiscitis type in 4, single level syndesmoph...

Baba, H.; Uchida, K.; Wada, M.; Imura, S.; Kawahara, N.; Tomita, K.

1997-01-01

299

Morphological characteristics of the bony birth canal in patients with developmental dysplasia of the hip (DDH). Investigation by three-dimensional CT  

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We investigated the three-dimensional morphological characteristics of the pelvis in adult female patients with developmental dysplasia of the hip (DDH), using computerized tomography (CT) images. Forty-two subjects with normal hips and 40 DDH patients were recruited for the study. In the DDH group, the average transverse diameter of the pelvic inlet was significantly less and the average transverse diameter of the pelvic outlet was significantly greater than the measurements in the normal group. Further, the bony birth canal in DDH patients exhibited a higher incidence of anthropoid-type geometry, as defined by a longer sagittal diameter relative to the transverse diameter of the pelvic inlet. These findings indicate a characteristic pelvic geometry and suggest different development of the pelvis in the transverse direction in DDH patients. In addition, the obstetric conjugate length/transverse diameter of the pelvic inlet ratio was correlated to the degree of severity of acetabular dysplasia. This finding suggests that DDH is a manifestation of a developmental characteristic of the pelvis. (author)

Kojima, Seiichi; Kobayashi, Seneki; Saito, Naoto; Nawata, Masashi; Horiuchi, Hiroshi; Takaoka, Kunio [Shinshu Univ., Matsumoto, Nagano (Japan). School of Medicine

2001-07-01

300

Pathology Case Study: Pigmented Lesion  

Science.gov (United States)

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 69-year-old man has a pigmented lesion on his right ear. Visitors are given the patient history and microscopic description, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in dermatologic pathology.

Ejadi, Samuel

2007-09-12

 
 
 
 
301

Characterization of different verrucous mucosal lesions.  

Science.gov (United States)

Oral lesions indicative of biopsy represent unique presentation either in the form of proliferations/ulcerations of the squamous lining epithelium. These lesions have similar appearance clinically and histopathologically hence are excised for microscopic evaluation to rule out early or hidden malignancy. Verrucous mucosal lesions clinically present a diagnostic dilemma, which makes histopathological examination a significant one in the differentiation of the lesion to ascertain the nature. This short communication aims to discuss the different histological characterization of oral verrucous mucosal lesions. PMID:24355971

Swetha, P; Supriya, Naga A; Kumar, Govind Raj N

2013-01-01

302

POEMS (polyneuropathy, organomegaly, endocrinopathy, M protein, skin lesions) syndrome: a South America's report / POEMS (polineuropatia, organomegalia, endocrinopatia, proteína M, alterações de pele): relato sul-americano  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in portuguese A síndrome POEMS, também conhecida como síndrome de Crow-Fukase é uma desordem sistêmica rara descrita principalmente em asiáticos. Ela é caracterizada pela presença de (P) polineuropatia, (O) organomegalia, (E) endocrinopatia, (M) proteína M e (S) alterações de pele. Diversas outras manifestações, [...] tais como lesões osteoescleróticas, doença de Castleman, febre baixa, edema e distúrbios hematológicos são freqüentemente observados. Apresentamos cinco pacientes brasileiros com esta síndrome. Dois pacientes apresentaram diagnóstico de doença de Castleman, um paciente com mieloma osteoesclerótico e em dois pacientes, nenhuma condição associada foi encontrada. Abstract in english The POEMS syndrome, also known as Crow-Fukase syndrome, is an unusual systemic disorder described mainly in Asian individuals. It is characterized by the presence of (P)polyneuropathy, (O)organomegaly, (E)endocrinopathy, (M) M-protein, and (S) skin changes. Several other associated condictions such [...] as sclerotic bone lesions, Castleman disease, low-grade fever, edema and hematologic disorders are usually seen. We describe five Brazilian patients with this syndrome. Two patients presented Castleman disease, one patient presented osteosclerotic myeloma and in two patients no associated conditions were found.

Leite, Ana Claudia Celestino; Nascimento, Osvaldo J.M.; Lima, Marco Antonio; Andrada-Serpa, Maria José.

303

POEMS (polyneuropathy, organomegaly, endocrinopathy, M protein, skin lesions syndrome: a South America's report POEMS (polineuropatia, organomegalia, endocrinopatia, proteína M, alterações de pele: relato sul-americano  

Directory of Open Access Journals (Sweden)

Full Text Available The POEMS syndrome, also known as Crow-Fukase syndrome, is an unusual systemic disorder described mainly in Asian individuals. It is characterized by the presence of (Ppolyneuropathy, (Oorganomegaly, (Eendocrinopathy, (M M-protein, and (S skin changes. Several other associated condictions such as sclerotic bone lesions, Castleman disease, low-grade fever, edema and hematologic disorders are usually seen. We describe five Brazilian patients with this syndrome. Two patients presented Castleman disease, one patient presented osteosclerotic myeloma and in two patients no associated conditions were found.A síndrome POEMS, também conhecida como síndrome de Crow-Fukase é uma desordem sistêmica rara descrita principalmente em asiáticos. Ela é caracterizada pela presença de (P polineuropatia, (O organomegalia, (E endocrinopatia, (M proteína M e (S alterações de pele. Diversas outras manifestações, tais como lesões osteoescleróticas, doença de Castleman, febre baixa, edema e distúrbios hematológicos são freqüentemente observados. Apresentamos cinco pacientes brasileiros com esta síndrome. Dois pacientes apresentaram diagnóstico de doença de Castleman, um paciente com mieloma osteoesclerótico e em dois pacientes, nenhuma condição associada foi encontrada.

Ana Claudia Celestino Leite

2007-06-01

304

Dieulafoy's lesion of duodenum: a case report  

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Full Text Available Abstract Background Dieulafoy's lesion is an uncommon but important cause of recurrent upper gastrointestinal bleeding. Extragastric location of Dieulafoy's lesion is rare. We report two cases of Dieulafoy's lesion of the duodenum and discuss the management of this extremely uncommon entity. Case presentation Two cases of massive upper gastro-intestinal bleeding in young adults due to Dieulafoy's lesion of the duodenum are reported. Endoscopic diagnosis was possible in both cases. Hemostasis was achieved successfully by endoscopic adrenaline injection. The endoscopic appearance, pitfalls in the diagnosis and management of this rare lesion are discussed. Conclusions Endoscopic diagnosis of extragastric Dieulafoy's lesion can be difficult because of the small size and obscure location of the lesion. Increased awareness and careful and early endoscopic evaluation following the bleeding episode are the key to accurate diagnosis. Adrenaline injection is one of the important endoscopic modalities for control of bleeding.

Wagholikar Gajanan D

2003-01-01

305

Leucocyte mobilization to skin lesions  

International Nuclear Information System (INIS)

Leucocyte mobilization to a chamber covering a skin lesion was studies in healthy volunteers."1"1"1Indium-labelled blood leucocytes accumulated in the chambers, indicating mobilization of leucocytes from the blood. The concentration of autologous serum in the chamber medium influenced the number of leucocytes mobilized, while heat inactivation of serum or the repeated use of the same serum had no effect on the counts. The use of zymosan-treated increased the mobilization by up to 53 %. The kinetics for the mobilization of leucocytes to chambers containing autologous serum was followed in healthy subjects. The mobilization showed a uniform pattern, viz. a lag phase of 2-4 hours and maximal migration rates after 20-24 hours. The cumulated counts were 74 x 10"6 leucocytes/cm"2/24 hours and 200 x 10"6leucocytes/cm"2/48 hours. Females and males exhibited the same kinetics and cumulated counts. Chamber leucocytes were predominantly neutrophil granulocytes (85-100 %) with 2.9-3.6 nuclear segments. The chamber technique provides a simple method permitting quantitation of in vivo mobilization of leucocytes from the blood to an inflammatory lesion. (author)

1980-01-01

306

Imaging in cardiac mass lesions  

International Nuclear Information System (INIS)

In 26 patients with cardiac mass lesions confirmed by surgery, diagnostic imaging was performed preoperatively by means of two-dimensional echocardiography (26 patients), angiography (12 patients), correlative computed tomography (CT, 8 patients), and magnetic resonance imaging (MRI, 3 patients). Two-dimensional echocardiography correctly identified the cardiac masses in all patients. Angiography missed two of 12 cardiac masses; CT missed one of eight. MRI identified three of three cardiac masses. Although the sensitivity of two-dimensional echocardiography was high (100%), all methods lacked specificity. None of the methods allowed differentiation between myxoma (n=13) and thrombus (n=7). Malignancy of the lesions was successfully predicted by noninvasive imaging methods in all six patients. However, CT and MRI provided additional information concerning cardiac mural infiltration, pericardial involvement, and extracardiac tumor extension, and should be integrated within a preoperative imaging strategy. Thus two-dimensional echocardiography is the method of choice for primary assessment of patients with suspected cardiac masses. Further preoperative imaging by CT or MRI can be limited to patients with malignancies suspected on the grounds of pericardial effusion or other clinical results. (author)

1992-01-01

307

Imaging in cardiac mass lesions  

Energy Technology Data Exchange (ETDEWEB)

In 26 patients with cardiac mass lesions confirmed by surgery, diagnostic imaging was performed preoperatively by means of two-dimensional echocardiography (26 patients), angiography (12 patients), correlative computed tomography (CT, 8 patients), and magnetic resonance imaging (MRI, 3 patients). Two-dimensional echocardiography correctly identified the cardiac masses in all patients. Angiography missed two of 12 cardiac masses; CT missed one of eight. MRI identified three of three cardiac masses. Although the sensitivity of two-dimensional echocardiography was high (100%), all methods lacked specificity. None of the methods allowed differentiation between myxoma (n=13) and thrombus (n=7). Malignancy of the lesions was successfully predicted by noninvasive imaging methods in all six patients. However, CT and MRI provided additional information concerning cardiac mural infiltration, pericardial involvement, and extracardiac tumor extension, and should be integrated within a preoperative imaging strategy. Thus two-dimensional echocardiography is the method of choice for primary assessment of patients with suspected cardiac masses. Further preoperative imaging by CT or MRI can be limited to patients with malignancies suspected on the grounds of pericardial effusion or other clinical results. (author).

Mundinger, A.; Gruber, H.P.; Dinkel, E.; Geibel, A.; Beck, A.; Wimmer, B.; Schlosser, V. (Freiburg Univ. (Germany))

308

[Distal radius fractures and concomitant lesions. Experimental studies concerning the pathomechanism].  

Science.gov (United States)

Since Colles (1814) first described a distal radius fracture and the publication by Dupuytren (1834), the frequency of and problems surrounding these fractures were increasingly recognised. Not only the treatment but also the formation and type of fracture were repeatedly analysed. The various theories concerning the pathomechanism led to names such as: "tear fracture", "bend fracture", "thrust fracture", "compression fracture", "snap fracture" and others. In our experimental studies we attempted to simulate the pathomechanism of distal radius fractures and present them pictorially. With the help of a materials testing machine, 63 prepared cadaver arms were hyperextended in the wrist joint until a radius fracture occurred. The concomitant lesions were registered radiologically and by dissection. Moreover, additional cadaver arms were deep-frozen and examined by means of computer tomography and cryosection according to Kathrein. Through experimental hyperextension it was possible to generate dorsal, central, and palmar types of fractures. We produced 42 dorsal, 14 central and 7 palmar fractures. Fundamentally, it seems that the fracture depends on the extent in which the carpal bones of the proximal row are pressed against the dorsal, central or palmar part of the articular surface of the distal radius. The subsequent dissection showed in 40 cases (63 %) mostly multiple concomitant lesions and in 23 cases (37 %) none of these. The reason for concomitant lesions may be the proportion of bone stability to the strength of ligaments. Most frequently (27 cases, i.e. 43 %), we found a destabilisation of the articular disk with or without a bony avulsion fragment (fracture of the ulnar styloid). We also commonly found ruptures of the interosseous ligaments between scaphoid and lunate (20 cases, i.e. 32 %) and lunate and triquetrum (11 cases, i.e. 18 %). It is difficult to apply knowledge gained from experimental studies on preserved cadaver arms clinically. There are of course no physiological reflexes and the slow fracture process must be taken into consideration. This holds true not only for concomitant lesions but also for the type of fracture. On the other hand, in these experimental studies it was possible to generate many realistic types of fractures with their concomitant lesions. PMID:12203148

Pechlaner, S; Kathrein, A; Gabl, M; Lutz, M; Angermann, P; Zimmermann, R; Peer, R; Peer, S; Rieger, M; Freund, M; Rudisch, A

2002-05-01

309

Detection of the Epstein-Barr Virus and DNA-Topoisomerase II-? in Recurrent and Nonrecurrent Giant Cell Lesion of the Jawbones  

Science.gov (United States)

The aims of this study were to determine whether the expression of Topo II-? correlates with presence of EBV in giant cell lesion of the jawbones and whether it is predictive of clinical biologic behavior of these lesions. Paraffin-embedded tissues from 8 recurrent and 7 nonrecurrent cases of bony GCLs and 9 peripheral giant cell lesions (PGCLs) as a control group were assessed for the expression of EBV and Topo II-? using immunohistochemistry. The results showed positive staining for Topo II-? in mononuclear stromal cells (MSCs) and multinucleated giant cells (MGCs). Student t-test showed that mean Topo II-? labelling index (LI) in recurrent cases was significantly higher than that in non-recurrent cases (P = 0.0001). Moreover, Spearman's correlation coefficients method showed a significant correlation between DNA Topo II-? LI and both of gender and site in these lesions. Moderate EBV expression in relation to the highest Topo II-? LI was observed in two cases of GCT. It was concluded that high Topo II-? LIs could be identified as reliable predicators for the clinical behavior of GCLs. Moreover, EBV has no etiological role in the benign CGCLs in contrast to its role in the pathogenesis of GCTs.

Zyada, Manal M.; Salama, Nagla M.

2013-01-01

310

Bony reconstruction by reposition of bony chips in suboccipital craniectomy  

Directory of Open Access Journals (Sweden)

Full Text Available In suboccipital craniectomy where the bone is not repositioned, there may be a significant cosmetic defect due to lack of skull bone in the suboccipital region. It may accompanied by sensory symptoms, including pain. To prevent any cosmetic defect and sensory symptoms we repositioned the bone chips at the craniectomy site in 42 suboccipital craniectomies before the closure of the scalp. At a mean follow-up of 22 months (range: 5-44 months, two patients complained of mild discomfort in the healed wound or of occasional local pain. One patient complained of mild itching at the site. In two patients, bone chips were accumulated at the lower part of the suboccipital craniectomy and failed to form a uniform bone cover at the operated site. In one patient, all bone chips were reabsorbed and there was no bone at the operated site. There was pseudomeningocele formation in one patient. In the rest of the cases there was satisfactory bone coverage at the operated site, both clinically and radiologically. The wound sites were aesthetically acceptable in 40 cases. Our study suggests that in the majority of cases where suboccipital craniotomy is not possible or not done, repositioning of the bone chips at the craniectomy site is associated with satisfactory aesthetic and functional outcome and formation of bone coverage at the operated site.

Chowdhury Forhad

2010-01-01

311

Anatomical Study of the Pterygospinous and Pterygoalar Bony Bridges and Foramens in Dried Crania and its Clinical Relevance Estudio Anatómico de los Puentes Óseos y Forámenes Pterigoespinoso y Pterigoalar en Cráneos Secos y su Relevancia Clínica  

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The ossification of the intrinsic ligaments of the sphenoid bone has been reported in the literature. The presence of bony bridges by ossification of the pterygospinous and pterygoalar ligaments has clinical significance in the infratemporal fossa contents. The purpose of this study is to analyze the prevalence of ossification of these ligaments and assess morphometrically the pterygospinous (Civinini's) and pterygoalar (crotaphitico-buccinatorius) foramens. A total of 312 human skulls from t...

Iván Suazo Galdames; Daniela Zavando Matamala; Ricardo Luiz Smith

2010-01-01

312

Bacteriology of diabetic foot lesions  

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Full Text Available Clinical grading and bacteriological study of 107 patients with diabetic foot lesions revealed polymicrobial aetiology in 69 (64.4% and single aetiology in 21 (19.6%. Among 107 patients 62 had ulcer. Of these 31 had mixed aerobes. Twenty six patients with cellulitis and 12 with gangrene had more than 5 types of aerobes and anaerobes such as E.coli, Klebsiella spp., Pseudomonas spp., Proteus spp., Enterobactor spp., Enterococci spp., Clostridium perfringens, Bacteroides spp., Prevotella spp. and Peptostreptococcus spp. It was noted that 50 out of 62 patients with ulcer, and all the patients with cellulitis and gangrene were given surgical management and treated with appropriate antibiotics based on antimicrobial susceptibility testing.

Anandi C

2004-01-01

313

Bony landmarks are not an adequate substitute for lymphangiography in defining pelvic lymph node location for the treatment of cervical cancer with radiotherapy  

International Nuclear Information System (INIS)

Purpose: Curative radiotherapy (RT) for carcinoma of the cervix requires adequate irradiation of regional lymph node groups. The best nonsurgical method of defining lymph node anatomy in the pelvis remains the lymphangiogram (LAG). This study was designed to determine if bony landmarks could accurately substitute for LAG as a means of determining lymph node position for the purpose of pelvic RT treatment planning. Methods and Materials: The post-LAG simulation films of 22 patients treated at the Fox Chase Cancer Center for cervical cancer were examined. On anterior/posterior (A/P) simulation films, the distance of lymph nodes was determined from the top, middle, and bottom of the sacroiliac joint, and at the pelvic rim, 1 and 2 cm above the acetabulum. On lateral (LAT) simulation films, lymph node position was measured at points 0, 4, and 8 cm along a line from the bottom of L5 to the anterior aspect of the pubic symphysis. Positive values represent lateral and anterior distances relative to the reference point on A/P and LAT films, respectively. Negative values represent distances in the opposite direction. The adequacy of standard pelvic fields as defined by the Gynecologic Oncology Group (GOG) (A/P: 1.5 cm margin on the pelvic rim; LAT field edge is a vertical line anterior to the pubic symphysis) was also examined. Data are expressed as the mean ± two standard deviations, (i.e. 95% confidence level). Results: On A/P simulation films, the distance of visualized lymph nodes had mean values of -1.6 ± 1.7 cm (range -4.1 to -0.4 cm), -1.3 ± 1.5 cm (range -3.4 to 0.0 cm), and 1.2 ± 1.8 cm (range -1.0 to 2.6 cm) from the sacro-iliac (SI) joint at the superior, middle, and inferior points, respectively. The mean distance of the nodes from the pelvic rim at points 1 and 2 cm above the acetabulum was 0.3 ± 1.2 cm (range -0.6 to 1.8 cm) and 0.2 ± 1.8 cm (range -1.6 to 2.1 cm), respectively. On LAT simulation films, the distance of lymph nodes from points 0, 4, and 8 cm from the previously described reference line had mean values of 2.0 ± 1.0 cm (range 1.3 to 3.0 cm), 0.9 ± 3.9 cm (range -1.9 to 5.1 cm), and 1.8 ± 2.1 cm (range -0.8 to 3.5 cm), respectively. Ten of 22 (45%) patients would have had inadequate nodal irradiation if their fields had been designed according to standard GOG parameters. In all cases, these incompletely irradiated lymph nodes were from the lowest of the lateral external iliac group. Conclusions: Great variability in pelvic lymph node location is demonstrated when LAG is used to directly visualize their location. Bony structures are inaccurate landmarks for pelvic lymph node position. The GOG standard pelvic fields are not consistently adequate to cover all lateral external iliac lymph nodes, although the clinical significance of this subgroup of lymph nodes is not known. At this time, LAG remains the ideal radiographic modality to define anatomic location of regional lymph nodes for pelvic RT treatment planning. The clinical importance of the most lateral group of external iliac lymph nodes in various stages of cervical cancer represents a potential area of future research

1996-01-01

314

Cutaneous lesions in new born.  

Science.gov (United States)

Five hundred unselected newborn babies delivered in the Department of Obstetrics and Gynaecology, Unit II of SGBT Hospital attached to Government Medical College, Amritsar during April 2000 to October 2000 were examined for cutaneous lesions daily for the first five days after birth. Different cutaneous lesions were seen in 474(94.8%) newborns. The physiological skin changes observed in order of frequency were Epstein pearls in 305(61%), Mongolian spot in 301(60.2%), superficial cutaneous desquamation in 200(40%), icterus in 128(25.6%), milia in 119(23.8%), sebaceous gland hyperplasia in 107(21.4%), occipital alopecia in 94(18.8%), lanugo in 72(14.4%), peripheral cyanosis in 47(9.4%), breast hypertrophy in 29(5.8%) and miniature puberty in 28(5.6%) newborns. Of the transient non-infective skin diseases, erythema toxicum neonatorum was observed most commonly in 105(21%), followed by miliaria rubra in 103(20.6%) and acne neonatorum in 27(5.4%) newborns. The naevi and other developmental defects in the descending order were salmon patch in 69(13.8%), congenital melanocytic noevi in 10(2%), accessory tragi in 3(0.6%), spina bifida in 2(0.4%), hydrocephalus in 1(0.2%) and poliosis in 1(0.2%) newborns. Cradle cap was the only dermatitis observed in 50(10%) newborns. One (0.2%) case each of Harlequin ichthyosis and labial cyst was seen. PMID:17656992

Sachdeva, Meenakshi; Kaur, Surjeet; Nagpal, Madhu; Dewan, S P

2002-01-01

315

Cutaneous lesions in new born  

Directory of Open Access Journals (Sweden)

Full Text Available Five hundred unselected newborn babies delivered in the Department of Obstetrics and Gynaecology, Unit II of SGBT Hospital attached to Government Medical College, Amritsar during April 2000 to October 2000 were examined for cutaneous lesions daily for the first five days after birth. Different cutaneous lesions were seen in 474(94. 8% newborns. The physiological skin changes observed in order of frequency were Epstein pearls in 305(61%, Mongolian spot in 301(60. 2%, superficial cutaneous desquamation in 200(40%, icterus in 128(25. 6%, milia in 119(23. 8%, sebaceous gland hyperplasia in 107 (21. 4%, occipital alopecia in 94(18. 8%, lanugo in 72(14. 4%, peripheral cyanosis in 47(9. 4%, breast hypertrophy in 29(5. 8% and miniature puberty in 28(5. 6% newborns. Of the transient non-infective skin diseases, erythema toxicum neonatorum was observed most commonly in 105(21 %, followed by miliaria rubra in 103(20. 6% and acne neonatorum in 27(5. 4% newborns. The naevi and other developmental defects in the descending order were salmon patch in 69(13. 8%, congenital melanocytic noevi in 10(2%, accessory tragi in 3(0.6%, spina bifida in 2(0.4%, hydrocephalus in 1(0.2% and poliosis in 1(0.2% newborns. Cradle cap was the only dermatitis observed in 50(10% newborns. One (0.2% case each of Harlequin ichthyosis and labial cyst was seen.

Sachdeva Meenakshi

2002-11-01

316

Early detection of bony alterations in rheumatoid and erosive arthritis of finger joints with high-resolution single photon emission computed tomography, and differentiation between them  

International Nuclear Information System (INIS)

To evaluate high-resolution multi-pinhole single photon emission computed tomography (MPH-SPECT) for the detection of bony alterations in early rheumatoid arthritis (ERA), early osteoarthritis (EOA) of the fingers and healthy controls. The clinically dominant hands of 27 patients (13 ERA, nine EOA, five healthy controls) were examined by MPH-SPECT and bone scintigraphy. Additionally, magnetic resonance imaging (MRI) was performed in the ERA patients. Number of affected joints, localisation, pattern of tracer distribution and joint involvement were scored. Quantitative analysis was achieved by measurement of the region of interest (ROI) in all patients. The MPH-SPECT and MR images were fused in the ERA group. Bone scintigraphy detected fewer joints (26 joints,13/22 patients) with increased tracer uptake than did MPH-SPECT (80 joints, 21/22 patients). Bone scintigraphy did not show recognisable uptake patterns in any group of patients. With MPH-SPECT central tracer distribution was typical in ERA (10/13 patients, EOA 2/9). In contrast, an eccentric pattern was found predominantly in EOA (7/9, ERA 2/13). Normalised counts were 4.5 in unaffected joints and up to 222.7 in affected joints. The mean uptake values in affected joints were moderately higher in the EOA patients (78.75, and 62.16 in ERA). The mean tracer uptake in affected joints was approximately three-times higher than in unaffected joints in both groups (ERA 3.64-times higher, EOA 3.58). Correlation with MR images revealed that bone marrow oedema and erosions matched pathological tracer accumulation of MPH-SPECT in 11/13. MPH-SPECT demonstrated increased activity in 2/13 patients with normal bone marrow signal intensity and synovitis seen on MR images. MPH-SPECT is sensitive to early changes in ERA and EOA and permits them to be distinguished by their patterns of uptake. (orig.)

2010-01-01

317

Early detection of bony alterations in rheumatoid and erosive arthritis of finger joints with high-resolution single photon emission computed tomography, and differentiation between them  

Energy Technology Data Exchange (ETDEWEB)

To evaluate high-resolution multi-pinhole single photon emission computed tomography (MPH-SPECT) for the detection of bony alterations in early rheumatoid arthritis (ERA), early osteoarthritis (EOA) of the fingers and healthy controls. The clinically dominant hands of 27 patients (13 ERA, nine EOA, five healthy controls) were examined by MPH-SPECT and bone scintigraphy. Additionally, magnetic resonance imaging (MRI) was performed in the ERA patients. Number of affected joints, localisation, pattern of tracer distribution and joint involvement were scored. Quantitative analysis was achieved by measurement of the region of interest (ROI) in all patients. The MPH-SPECT and MR images were fused in the ERA group. Bone scintigraphy detected fewer joints (26 joints,13/22 patients) with increased tracer uptake than did MPH-SPECT (80 joints, 21/22 patients). Bone scintigraphy did not show recognisable uptake patterns in any group of patients. With MPH-SPECT central tracer distribution was typical in ERA (10/13 patients, EOA 2/9). In contrast, an eccentric pattern was found predominantly in EOA (7/9, ERA 2/13). Normalised counts were 4.5 in unaffected joints and up to 222.7 in affected joints. The mean uptake values in affected joints were moderately higher in the EOA patients (78.75, and 62.16 in ERA). The mean tracer uptake in affected joints was approximately three-times higher than in unaffected joints in both groups (ERA 3.64-times higher, EOA 3.58). Correlation with MR images revealed that bone marrow oedema and erosions matched pathological tracer accumulation of MPH-SPECT in 11/13. MPH-SPECT demonstrated increased activity in 2/13 patients with normal bone marrow signal intensity and synovitis seen on MR images. MPH-SPECT is sensitive to early changes in ERA and EOA and permits them to be distinguished by their patterns of uptake. (orig.)

Ostendorf, B.; Schneider, M. [Heinrich-Heine University, Rheumatology, Department of Endocrinology, Diabetology and Rheumatology, Duesseldorf (Germany); Mattes-Gyoergy, K.; Wirrwar, A.; Mueller, H.W. [Heinrich-Heine University, Department of Nuclear Medicine, Duesseldorf (Germany); Reichelt, D.C.; Blondin, D.; Lanzman, R.; Moedder, U.; Scherer, A. [Heinrich-Heine University, Institute of Radiology, Duesseldorf (Germany)

2010-01-15

318

Evaluation of HTR polymer (Bioplant® HTR® as a bone graft material in the treatment of interproximal vertical bony defects: A clinical and radiological study  

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Full Text Available Background and Objectives : Bone grafting is the most common form of regenerative therapy. Several bone substitutes have been used in clinical periodontal therapy to encourage bone formation. The present study has been undertaken to evaluate the efficacy of hard tissue replacement polymer (Bioplant® HTR® as a bone graft material in the treatment of interproximal vertical bony defects in human beings, both clinically and radiologically. Materials and Methods : Five chronic periodontitis patients were selected with 16 sites assigned randomly into control (open debridement alone and experimental (open flap debridement plus Bioplant® HTR® groups. Clinical measurements like plaque index (PI, gingival index (GI, probing pocket depth (PPD, clinical attachment level (CAL, gingival margin position (GMP assessment was done at 0, 3 and 6 months and radiographic assessment at 0 and 6 month. Statistical analysis was performed using Wilcoxon?s signed Rank test and Mann-whitney U-test. Results : There were statistically no significant (P=1.00 changes in Plaque index and Gingival Index scores in both the groups from baseline to six months post surgery. Statistically significant (P< 0.05 reduction in Probing Pocket Depth was seen on comparison between the groups. In relation to the hard tissue changes, significant results were seen with respect to change in alveolar crest and percentage of original defect resolved. Comparison of results from six to 12 months following similar treatments showed no significant differences or advantages to having a clinical evaluation period longer than 6 months post surgically (Yukna 1999. Interpretation and Conclusion : Bioplant® HTR® material is a biocompatible, easy to handle and a beneficial grafting material for the treatment of periodontal osseous defects.

Prakash Shobha

2010-01-01

319

Using an extreme bony prominence anatomical model to examine the influence of bed sheet materials and bed making methods on the distribution of pressure on the support surface.  

Science.gov (United States)

Bed sheets generate high surface tension across the support surface and increase pressure to the body through a process known as the hammock effect. Using an anatomical model and a loading device characterized by extreme bony prominences, the present study compared pressure distributions on support surfaces across different bed making methods and bed sheet materials to determine the factors that influence pressure distribution. The model was placed on a pressure mapping system (CONFORMat; NITTA Corp., Osaka, Japan), and interface pressure was measured. Bed sheet elasticity and friction between the support surface and the bed sheets were also measured. For maximum interface pressure, the relative values of the following methods were higher than those of the control method, which did not use any bed sheets: cotton sheets with hospital corners (1.28, p = 0.02), polyester with no corners (1.29, p = 0.01), cotton with no corners (1.31, p = 0.003), and fitted polyester sheets (1.35, p = 0.002). Stepwise multiple regression analysis indicated that maximum interface pressure was negatively correlated with bed sheet elasticity (R(2) = 0.74). A statistically significant negative correlation was observed between maximum interface pressure and immersion depth, which was measured using the loading device (r = -0.40 and p = 0.04). We found that several combinations of bed making methods and bed sheet materials induced maximum interface pressures greater than those observed for the control method. Bed sheet materials influenced maximum interface pressure, and bed sheet elasticity was particularly important in reducing maximum interface pressure. PMID:24524899

Iuchi, Terumi; Nakajima, Yukari; Fukuda, Moriyoshi; Matsuo, Junko; Okamoto, Hiroyuki; Sanada, Hiromi; Sugama, Junko

2014-05-01

320

Bony destructive injuries of the calcaneus: long-term results of a minimally invasive procedure followed by early functional exercise: a retrospective study  

Science.gov (United States)

Background Bony destructive injury of the calcaneus (BDIC) represents one of the most severe comminuted fractures of the calcaneus in which soft tissue coverage remains intact. The features of this injury include a collapsed articular surface, significant widening, severe loss of height and an unrecognisable outline of the calcaneus. This study aims to present the long-term outcomes of BDIC treated in a minimally invasive fashion followed by supervised early exercise. Methods Twelve patients with unilateral BDICs were treated at our institution. The main surgical procedures included percutaneous traction and leverage reduction and internal compression fixation with anatomic plates and compression bolts. Early functional exercise was encouraged to mould the subtalar joint. The height, length and width of the calcaneus; Böhler’s and Gissane’s angles; reduction of the articular surfaces; and functional recovery of the affected feet were assessed. Results The height, length and width of the calcaneus were substantially restored. The mean Böhler’s and Gissane’s angles of the affected calcaneus were 24.5 and 122.8 degrees, respectively. Five patients regained anatomical or nearly anatomical reduction of their posterior facets. Residual articular displacement of more than 3 mm was noted in three patients. Patients were followed for a mean of 93.9 months. The mean American Orthopaedic Foot and Ankle Society score was 83.8. Nine patients showed excellent or good results. Radiographic evidence of post-traumatic subtalar arthritis was observed in four cases. However, no subtalar arthrodesis was required. Conclusions BDICs can be treated effectively with percutaneous reduction and internal compression fixation followed by early active exercise. This protocol resulted in satisfactory radiological and functional outcomes.

2014-01-01

 
 
 
 
321

The Felix-trial. Double-blind randomization of interspinous implant or bony decompression for treatment of spinal stenosis related intermittent neurogenic claudication  

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Full Text Available Abstract Background Decompressive laminotomy is the standard surgical procedure in the treatment of patients with canal stenosis related intermittent neurogenic claudication. New techniques, such as interspinous process implants, claim a shorter hospital stay, less post-operative pain and equal long-term functional outcome. A comparative (cost- effectiveness study has not been performed yet. This protocol describes the design of a randomized controlled trial (RCT on (cost- effectiveness of the use of interspinous process implants versus conventional decompression surgery in patients with lumbar spinal stenosis. Methods/Design Patients (age 40-85 presenting with intermittent neurogenic claudication due to lumbar spinal stenosis lasting more than 3 months refractory to conservative treatment, are included. Randomization into interspinous implant surgery versus bony decompression surgery will take place in the operating room after induction of anesthesia. The primary outcome measure is the functional assessment of the patient measured by the Zurich Claudication Questionnaire (ZCQ, at 8 weeks and 1 year after surgery. Other outcome parameters include perceived recovery, leg and back pain, incidence of re-operations, complications, quality of life, medical consumption, absenteeism and costs. The study is a randomized multi-institutional trial, in which two surgical techniques are compared in a parallel group design. Patients and research nurses are kept blinded of the allocated treatment during the follow-up period of 1 year. Discussion Currently decompressive laminotomy is the golden standard in the surgical treatment of lumbar spinal stenosis. Whether surgery with interspinous implants is a reasonable alternative can be determined by this trial. Trial register Dutch Trial register number: NTR1307

Brand Ronald

2010-05-01

322

[Labrum lesions in residual dysplasia of the hip joint. Biomechanical considerations on pathogenesis and treatment].  

Science.gov (United States)

The capsular-labrum-complex consists of the triangular fibrocartilaginous labrum, which is fixed at the bony acetabular ring and supported by the ligamentum transversum actetabuli in the caudal part. In a normally developed and correctly orientated acetabulum, the femoral head is symmetrically covered by the contact area of the lunate surface. The vertical component of the resultant hip joint force concentrically meets the horizontal weight bearing surface: Evenly distributed compressive forces are transmitted; the capsular-labrum-complex does not have to compensate excessive shear or tension. In contrast, in a "dysplastic" acetabulum the femoral head is poorly covered by the pathologically orientated lunate surface: The lunate surface is sloping in an anterolateral direction, leading to tension and shear on the superolateral capsular-labrum-complex, which becomes a secondary stabilizer ("guide rail") against the decentering femoral head. The vertical component of the resultant hip force eccentrically meets the oblique weight bearing surface, causing extra stress in the labrum: The capsular-labrum-complex is trying to compensate this biomechanical stress with hypertrophy (Type IB). Progressive mechanical decompensation of the capsular-labral-complex might lead to tears (Type IIB) or complete avulsions (Type IIIB) of the labrum. In conclusion labral lesions result from pathobiomechanics caused by residual hip dysplasia (RHD). Logically, the basic therapeutic principle can only be corrective osteotomy. PMID:9871920

Tschauner, C; Hofmann, S

1998-11-01

323

Natural history of bronchial preinvasive lesions  

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Preinvasive bronchial lesions defined as dysplasia and carcinoma in situ (CIS) have been considered as precursors of squamous cell carcinoma of the lung. The risk and rate of progression of preinvasive lesions to invasive squamous cell carcinoma as well as the mechanism of progression or regression are incompletely understood. While the evidence for the multistage, stepwise progression model is weak with relatively few documented lesions that progress through various grades of dysplasia to CI...

2010-01-01

324

Radiologic aspects of the Galeazzi lesion  

International Nuclear Information System (INIS)

In lesions of the forearm that included a fracture of the distal two thirds of the radial shaft, a concomitant disruption of the distal radio-ulnar joint was found in 20 out of 38 cases. In 15 cases a typical Galeazzi lesion was present. Dislocation of the distal radio-ulnar joint frequently goes unrecognized. The clinical significance of a lesion in the distal radio-ulnar joint is related to its prognostic value. (orig.)

1984-08-01

325

Radiologic aspects of the Galeazzi lesion  

Energy Technology Data Exchange (ETDEWEB)

In lesions of the forearm that included a fracture of the distal two thirds of the radial shaft, a concomitant disruption of the distal radio-ulnar joint was found in 20 out of 38 cases. In 15 cases a typical Galeazzi lesion was present. Dislocation of the distal radio-ulnar joint frequently goes unrecognized. The clinical significance of a lesion in the distal radio-ulnar joint is related to its prognostic value.

Carvalho, A. de; Meoller, J.T.; Vestergaard-Andersen, T.

1984-08-01

326

Polypoid Lesions of the Gallbladder in Children  

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Polypoid lesions of the gallbladder in children are rare. We report a case of a gallbladder polyp in a 14-year-old boy who presented with recurrent right upper quadrant abdominal pain. Ultrasound examination of the abdomen revealed a polypoid lesion of the gallbladder. His symptoms resolved after laparoscopic cholecystectomy. Histological examination of the gallbladder demonstrated a benign adenomatous polyp. Although the experience with polypoid lesions of the gallbladder in children is limi...

Stringel, Gustavo; Beneck, Debra; Bostwick, Howard E.

1997-01-01

327

Space Occupying Lesions in the Liver  

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"nRadiology (imaging) plays a pivotal role for the diagnosis, staging, treatment planning, and follow-up of focal liver lesions. The differential diagnosis in patients presenting with a focal liver lesion is broad. "nThe size of the liver mass is an important consideration in guiding the evaluation. Lesions smaller than approximately 1.0 cm are commonly benign incidental findings on imaging studies, and in most cases represent small cysts, hemangiomas, or biliary hamartomas. Further...

Nasser Ebrahimi Daryani

2009-01-01

328

Profile of osteolytic lesions on bone scan  

International Nuclear Information System (INIS)

Full text: Retrospective analysis of 35 osteolytic lesions seen radiologically was done. All the patients were subjected to three-phase bone scintigraphy. They were categorized into Category 1: Vascular (n = 10), Category 2: Nonvascular (n = 25). The nonvascular lesions were sub classified into those associated without biochemical evidence of metabolic bone disease (Class A) and those with biochemical as well as scan evidence of metabolic bone disease (Class B). Class B was divided into B1 - Osteomalacia and B2 - Hyperparathyroidism. In Category 1: 9/10 lesions were malignant. 1/10 lesion had septic arthritis. In Category 2: Class A - 3/15 had malignancy. (2 metastases, 1 plasmacytoma). (The nonmalignant lesions were 4 Fibrous dysplasia, 1 Eosinophilic granuloma, 4 Bone cysts, 1 Osteoid osteoma, 1 Avascular necrosis, 1 Inflammatory). Class B1 (n = 5) had low serum calcium, normal or high serum phosphorous, and high serum alkaline phosphatase. Class B2 (n = 5) has high serum calcium, low or normal serum phosphorous, high serum alkaline phosphatase and high serum parathyroid hormone level. Parathyroid scanning in-group B2 revealed parathyroid adenomas in the neck as the cause of hyperparathyroidism. It was observed that majority of vascular osteolytic lesions were malignant (90%). 75% of malignant lesions had evidence of hypervascularity on first and second phase (9/12). 80% of nonvascular lesions were benign. Metabolic bone disease is a frequent cause of osteolytic lesions (28.5%). (author)

2004-01-01

329

MR imaging of sacral and perisacral lesions  

International Nuclear Information System (INIS)

This exhibit demonstrates the utility of MR imaging in evaluating sacral and perisacral lesions. Thirty-two lesions were studied using a superconducting 1.0-T MR imager. Eleven primary and 13 metastatic tumors, four congenital lesions, and four arachnoid cysts were evaluated. MR did not usually enable a more specific histologic diagnosis than other imaging techniques. However, extraosseous and proximal spinal extent of tumors was well defined without use of oral or intravenous contrast material. MR imaging is an excellent noninvasive technique for evaluating most sacral and perisacral lesions and is particularly helpful when precise tumor extent must be determined for treatment planning

1987-12-04

330

Cold lesions demonstrated on bone scintigraphy  

International Nuclear Information System (INIS)

Localized areas of decreased radioactivity in the bone were demonstrated in 17 cases (1.4%) of 1,213 bone scintigrams performed with Tc-99m diphosphonate. In 15 out of 17 cases ''cold'' bone lesions were found to be metastatic bone cancers. Primary sites of cancers included the lung (7 cases), uterine cervix (3 cases), thyroid (2 cases), kidney (1 case), prostate (1 case) and pancreas (1 case). Other two lesions were found in primary site of chondroblastoma and metastatic site of osteosarcoma. Histological studies revealed squamous cell carcinoma in all 7 patients with lung cancer. Whereas ''hot'' bone lesions were found in 56% of adenocarcinoma and 31% of squamous cell carcinoma of the lung. High incidence of ''cold'' bone lesions were found in 3 (21%) out of 14 patients with cervical cancer who revealed positive bone scans. Abnormal bone scintigrams were found in 50 of 160 cases with breast cancer, but none of them showed ''cold'' bone lesions. In 14 cases increased uptake of radioactivity is noted around the cold lesions. Increased Ga-67 uptake in the ''cold'' lesion was found in 6 cases of lung cancer. Increased uptake of Tl-201 was found in the ''cold'' lesions in two patients with thyroid cancer. Postulated factors causing cold bone lesions were discussed reviewing literatures. (author)

1980-01-01

331

Inter- and intra-observer variability associated with the use of the Mirels' scoring system for metastatic bone lesions.  

LENUS (Irish Health Repository)

Metastatic bone disease is increasing in association with ever-improving medical management of osteophylic malignant conditions. The precise timing of surgical intervention for secondary lesions in long bones can be difficult to determine. This paper aims to evaluate a classic scoring system. All radiographs were examined twice by three orthopaedic oncologists and scored according to the Mirels\\' scoring system. The Kappa statistic was used for the purpose of statistical analysis. The results show agreement between observers (??=?0.35-0.61) for overall scores at the two time intervals. Inter-observer agreement was also seen with subset analysis of size (??=?0.27-0.60), site (??=?0.77-1.0) and nature of the lesion (??=?0.55-0.81). Similarly, low levels of intra-observer variability were noted for each of the three surgeons (?=?0.34, 0.39, and 0.78, respectively). These results indicate a reliable, repeatable assessment of bony metastases. We continue to advocate its use in the management of patients with long bone metastases.

Mac Niocaill, Ruairi F

2011-01-01

332

High-resolution CT with histopathological correlates of the classic metaphyseal lesion of infant abuse  

Energy Technology Data Exchange (ETDEWEB)

The classic metaphyseal lesion (CML) is a common high specificity indicator of infant abuse and its imaging features have been correlated histopathologically in infant fatalities. High-resolution CT imaging and histologic correlates were employed to (1) characterize the normal infant anatomy surrounding the chondro-osseous junction, and (2) confirm the 3-D model of the CML previously inferred from planar radiography and histopathology. Long bone specimens from 5 fatally abused infants, whose skeletal survey showed definite or suspected CMLs, were studied postmortem. After skeletal survey, selected specimens were resected and imaged with high-resolution digital radiography. They were then scanned with micro-CT (isotropic resolution of 45 ?m{sup 3}) or with high-resolution flat-panel CT (isotropic resolutions of 200 ?m{sup 3}). Visualization of the bony structures was carried out using image enhancement, segmentation and isosurface extraction, together with volume rendering and multiplanar reformatting. These findings were then correlated with histopathology. Study of normal infant bone clarifies the 3-D morphology of the subperiosteal bone collar (SPBC) and the radiographic zone of provisional calcification (ZPC). Studies on specimens with CML confirm that this lesion is a fracture extending in a planar fashion through the metaphysis, separating a mineralized fragment. This disk-like mineralized fragment has two components: (1) a thick peripheral component encompassing the SPBC; and (2) a thin central component comprised predominantly of the radiologic ZPC. By manipulating the 3-D model, the varying appearances of the CML are displayed. High-resolution CT coupled with histopathology provides elucidation of the morphology of the CML, a strong indicator of infant abuse. This new information may prove useful in assessing the biomechanical factors that produce this strong indicator of abusive assaults in infants. (orig.)

Tsai, Andy; Kleinman, Paul K. [Boston Children' s Hospital, Department of Radiology, Boston, MA (United States); McDonald, Anna G. [Office of the Chief Medical Examiner, Boston, MA (United States); Rosenberg, Andrew E. [University of Miami Hospital, Department of Pathology, Miami, FL (United States); Gupta, Rajiv [Massachusetts General Hospital, Department of Radiology, Boston, MA (United States)

2014-02-15

333

Human papillomavirus in oral lesions Virus papiloma humano en lesiones orales  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Growing evidence suggests a role for human papillomavirus (HPV) in oral cancer; however its involvement is still controversial. This study evaluates the frequency of HPV DNA in a variety of oral lesions in patients from Argentina. A total of 77 oral tissue samples from 66 patients were selected (cases); the clinical-histopathological diagnoses corresponded to: 11 HPV- associated benign lesions, 8 non-HPV associated benign lesions, 33 premalignant lesions and 25 cancers. Sixty exfoliated cell ...

Go?nzalez, Joaqui?n V.; Gutie?rrez, Rafael A.; Alicia Keszler; Maria Del Carmen Colacino; Alonio, Lidia V.; Teyssie, Ange?lica R.; Maria Alejandra Picconi

2007-01-01

334

MR of post traumatic spinal cord lesions. Unexpected improvement of hemorrhagic lesions.  

Science.gov (United States)

Fifteen patients who sustained spinal cord trauma were evaluated by MR within 72 hours of injury. Nine patients had hemorrhagic and six had nonhemorrhagic traumatic spinal cord lesions. Three patients with hemorrhagic and all six patients with nonhemorrhagic lesions showed some degree of neurological improvement on follow-up examinations. In two of the three patients with hemorrhagic lesions who improved, the hemorrhage was extensive. This supports the observation that hemorrhagic lesions are not always associated with a poor clinical outcome. PMID:9215470

Wasenko, J J; Hochhauser, L; Holsapple, J W; Poe, L B; Albanese, S A; Cacayorin, E D

1997-01-01

335

Evaluation of hepatic cystic lesions.  

Science.gov (United States)

Hepatic cysts are increasingly found as a mere coincidence on abdominal imaging techniques, such as ultrasonography (USG), computed tomography (CT) and magnetic resonance imaging (MRI). These cysts often present a diagnostic challenge. Therefore, we performed a review of the recent literature and developed an evidence-based diagnostic algorithm to guide clinicians in characterising these lesions. Simple cysts are the most common cystic liver disease, and diagnosis is based on typical USG characteristics. Serodiagnostic tests and microbubble contrast-enhanced ultrasound (CEUS) are invaluable in differentiating complicated cysts, echinococcosis and cystadenoma/cystadenocarcinoma when USG, CT and MRI show ambiguous findings. Therefore, serodiagnostic tests and CEUS reduce the need for invasive procedures. Polycystic liver disease (PLD) is arbitrarily defined as the presence of > 20 liver cysts and can present as two distinct genetic disorders: autosomal dominant polycystic kidney disease (ADPKD) and autosomal dominant polycystic liver disease (PCLD). Although genetic testing for ADPKD and PCLD is possible, it is rarely performed because it does not affect the therapeutic management of PLD. USG screening of the liver and both kidneys combined with extensive family history taking are the cornerstone of diagnostic decision making in PLD. In conclusion, an amalgamation of these recent advances results in a diagnostic algorithm that facilitates evidence-based clinical decision making. PMID:23801855

Lantinga, Marten A; Gevers, Tom J G; Drenth, Joost P H

2013-06-21

336

Evaluation of hepatic cystic lesions  

Directory of Open Access Journals (Sweden)

Full Text Available Hepatic cysts are increasingly found as a mere coincidence on abdominal imaging techniques, such as ultrasonography (USG, computed tomography (CT and magnetic resonance imaging (MRI. These cysts often present a diagnostic challenge. Therefore, we performed a review of the recent literature and developed an evidence-based diagnostic algorithm to guide clinicians in characterising these lesions. Simple cysts are the most common cystic liver disease, and diagnosis is based on typical USG characteristics. Serodiagnostic tests and microbubble contrast-enhanced ultrasound (CEUS are invaluable in differentiating complicated cysts, echinococcosis and cystadenoma/cystadenocarcinoma when USG, CT and MRI show ambiguous findings. Therefore, serodiagnostic tests and CEUS reduce the need for invasive procedures. Polycystic liver disease (PLD is arbitrarily defined as the presence of > 20 liver cysts and can present as two distinct genetic disorders: autosomal dominant polycystic kidney disease (ADPKD and autosomal dominant polycystic liver disease (PCLD. Although genetic testing for ADPKD and PCLD is possible, it is rarely performed because it does not affect the therapeutic management of PLD. USG screening of the liver and both kidneys combined with extensive family history taking are the cornerstone of diagnostic decision making in PLD. In conclusion, an amalgamation of these recent advances results in a diagnostic algorithm that facilitates evidence-based clinical decision making.

Marten A Lantinga

2013-01-01

337

Nora's lesion of the second toe  

Science.gov (United States)

Bizarre parosteal osteochondromatous proliferation, otherwise known as Nora’s lesion, is surface tumor of bone with high probability of local recurrence. The author reports a case of Nora’s lesion of the proximal phalanx of the second toe, successfully managed by en bloc excision of the swelling. At four-year follow-up there was no evidence of recurrence.

Suresh, SS

2010-01-01

338

Congenital cystic lesions of the biliary tree  

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OBJECTIVE: The purpose of this essay is to illustrate the imaging findings of congenital cystic lesions of the biliary tract. CONCLUSION: Congenital cystic lesions of the biliary tract include ductal plate malformations and choledochal cysts and can be recognized with characteristic imaging findings and basic knowledge of the embryologic development of the biliary tree.

Santiago, I.; Loureiro, R.; Curvo-semedo, L.; Marques, C.; Tarda?guila, F.; Matos, C.; Caseiro-alves, F.

2012-01-01

339

Radiological features of excavated pulmonary tumoral lesions  

International Nuclear Information System (INIS)

The clinical and radiological features of 43 cases of primitive and metastatic excavated pulmonary tumoral lesions are analysed. The clinical signs and ssymptoms, sex, color, habits of life, histologic classification of the excavated primitive and metastatic lesions, size and thickness of the excavated tumoral nodules and their roentgenographic characteristics are studied. (Author)

1986-01-01

340

Pure extradural approach for skull base lesions.  

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Full Text Available Lesions in the parasellar and paracavernous regions can be removed by various skull base approaches involving basal osteotomies. A major complication of intradural skull base approaches is CSF leak and associated meningitis. We have managed 5 patients with skull base lesions with a pure extradural approach using wide basal osteotomies. The operative techniques are described.

Gupta S

1999-10-01

 
 
 
 
341

The recognition of lesions on chest radiographs  

International Nuclear Information System (INIS)

An approach to the recognition of lesions on chest radiographs is outlined. Four basic groups of abnormalities by means of which lesions can be recognized are mentioned and are briefly described, namely an opacity, an area of increased translucency, a combination of an opacity and an area of increased translucency, and, especailly, an alteration in normal radiological anatomy

1979-05-12

342

Clinical and cyto-histopathological evaluation of skin lesions with special reference to bullous lesions  

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Full Text Available Aim: Cytopathology of skin has been documented to be useful in the diagnosis of several skin lesions. This study aims to evaluate cytopathology as a quick non-invasive method for early diagnosis of bullous lesions, neoplastic and preneoplastic skin lesions and to correlate the clinical, cytological and histopathological findings of various skin lesions. Materials and Methods: Eighty five patients of skin lesions were included in the study. Skin scraping, Tzanck smears, slit smears and fine needle aspiration cytology (FNAC were done to obtain material for cytological examination. Excisional biopsy, incisional biopsy and punch biopsy were done to obtain tissue for histopathological examination. The slides were stained with routine stains and special stains as and when required. Results: Of the 85 patients, 45 were males and 40 females. The most common non-neoplastic lesions observed were vesicobullous lesions which comprised of 41 cases followed by neoplastic lesions which consisted of 24 cases, of which six were benign and 18 malignant. Concordant results between cytology and histopathology was seen in majority (91.7% of lesions studied. Conclusion: Cytology (scrape/imprint/slit smears and FNAC, performed skillfully and with perfection, leads to an early diagnosis in majority of the lesions, as the observed cytomorphological features of various skin lesions were fairly distinctive making cytology a fairly sensitive ?patient compliant? technique for rapid diagnosis of skin lesions.

Sabir Fauziya

2010-01-01

343

Suprasellar lesions: evaluation with MR imaging.  

Science.gov (United States)

The authors retrospectively evaluated the characteristics on magnetic resonance (MR) images of 59 suprasellar lesions and compared them with computed tomography (CT) scans in 55 of the cases in which CT was performed. A diverse number of lesions were included: 17 pituitary adenomas; eight optic or hypothalamic gliomas; six craniopharyngiomas; six vascular anomalies; four lesions with extension into the suprasellar space; three metastases; two each of meningioma, hamartoma, germinoma, sarcoid granuloma, and teratoma; and one each of lymphoma, optic tract hematoma, cerebrospinal fluid-borne metastasis, pituitary hyperplasia, and sphenoid sinus mucocele. MR enabled characterization of lesions containing hemorrhage, fat, flowing blood, mucus, and cyst and allowed more specific diagnoses than CT in 6% of cases. MR was equivalent to CT in allowing lesions to be detected and in 20% of cases more accurately defined altered perisellar anatomy. Vascular abnormalities can be better evaluated with MR, and use of angiography can be avoided in some cases. PMID:3763887

Karnaze, M G; Sartor, K; Winthrop, J D; Gado, M H; Hodges, F J

1986-10-01

344

Bone scintigraphy in lesions of the skull  

International Nuclear Information System (INIS)

The value of 3-phase-scintigraphy in bone lesions of the skull with a new seeking agent 99mTc-2,3-dicarboxypropane-1,1-diphosphonic acid (DPD) is studied. A high soft tissue-bone-ratio of DPD is emphasized. For this reason DPD is used for bone scintigraphy of the skull, because the mass of soft tissue in relation to bone is high and a higher clearance improves the interpretation of the images of the first two phases. An increased tracer uptake is found for skeletal neoplasms (malignant and benign lesions) and for acute osteomyelitis. By contrast, the chronic inflammatory bone lesions showed normal tracer uptake. This new bone seeking agent allows to localize and differentiate tumorous or acute inflammatory lesions and chronic inflammatory bone lesions of the skull

1982-09-02

345

Development of mandibular, hyoid and hypobranchial muscles in the zebrafish: homologies and evolution of these muscles within bony fishes and tetrapods  

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Full Text Available Abstract Background During vertebrate head evolution, muscle changes accompanied radical modification of the skeleton. Recent studies have suggested that muscles and their innervation evolve less rapidly than cartilage. The freshwater teleostean zebrafish (Danio rerio is the most studied actinopterygian model organism, and is sometimes taken to represent osteichthyans as a whole, which include bony fishes and tetrapods. Most work concerning zebrafish cranial muscles has focused on larval stages. We set out to describe the later development of zebrafish head muscles and compare muscle homologies across the Osteichthyes. Results We describe one new muscle and show that the number of mandibular, hyoid and hypobranchial muscles found in four day-old zebrafish larvae is similar to that found in the adult. However, the overall configuration and/or the number of divisions of these muscles change during development. For example, the undivided adductor mandibulae of early larvae gives rise to the adductor mandibulae sections A0, A1-OST, A2 and A?, and the protractor hyoideus becomes divided into dorsal and ventral portions in adults. There is not always a correspondence between the ontogeny of these muscles in the zebrafish and their evolution within the Osteichthyes. All of the 13 mandibular, hyoid and hypobranchial muscles present in the adult zebrafish are found in at least some other living teleosts, and all except the protractor hyoideus are found in at least some extant non-teleost actinopterygians. Of these muscles, about a quarter (intermandibularis anterior, adductor mandibulae, sternohyoideus are found in at least some living tetrapods, and a further quarter (levator arcus palatini, adductor arcus palatini, adductor operculi in at least some extant sarcopterygian fish. Conclusion Although the zebrafish occupies a rather derived phylogenetic position within actinopterygians and even within teleosts, with respect to the mandibular, hyoid and hypobranchial muscles it seems justified to consider it an appropriate representative of these two groups. Among these muscles, the three with clear homologues in tetrapods and the further three identified in sarcopterygian fish are particularly appropriate for comparisons of results between the actinopterygian zebrafish and the sarcopterygians.

Hinits Yaniv

2008-02-01

346

Dopamine-Mediated Sclerotization of Regenerated Chitin in Ionic Liquid  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Chitin is a promising structural material for biomedical applications, due to its many advantageous properties and abundance in nature. However, its usage and development in the biomedical field have been stagnant, because of chitin’s poor mechanical properties in wet conditions and the difficulties in transforming it into an applicable form. To overcome these challenges, we created a novel biomimetic chitin composite. This regenerated chitin, prepared with ionic liquid, showed improved mec...

Oh, Dongyeop X.; Sara Shin; Chanoong Lim; Dong Soo Hwang

2013-01-01

347

Congenital granular cell lesion in newborn mandible.  

Science.gov (United States)

Congenital granular cell lesion (CGCL) is a rare non-neoplastic lesion found in newborns also known as Neumann's tumor. This benign lesion occurs predominantly in females mostly as a single mass. The histogenesis and natural history of the lesion remains obscure. It arises from the mucosa of the gingiva, either from the maxillary or mandibular alveolar ridge. The lesion is more common in the maxillary alveolar ridge than the mandibular.The present report describes a case of congenital granular cell lesion in an eight-day-old female child who was born with a mass on the anterior mandibular alveolar ridge. The mass was protruding from her mouth and compromised feeding. A clinical diagnosis of teratoma was suggested. Histologically, cells of this lesion are identical to granular cell tumor (neuroectodermal type) and show intense diastase-resistant Periodic Acid Schiff positivity. Immunohistochemically, cells are positive for vimentin but negative for S-100 and desmin, thus suggesting that CGCL is possibly derived from primitive gingival mesenchymal cells rather than having schwannian origin. PMID:23771472

Gupta, O; Arora, R; Gupta, K; Sharma, U

2013-01-01

348

Polypoidal lesions in the nasal cavity.  

Science.gov (United States)

Introduction: Nasal polyps are polypoidal masses arising from mucous membranes of nose and paranasal sinuses. They are overgrowths of the mucosa that frequently accompany allergic rhinitis. They are freely movable and nontender. Aims and Objectives: The purpose of this study was to study the histopathologic spectrum of polypoidal lesions of the nasal cavity. Materials and Methods: The study comprised of 100 consecutive cases of polypoidal lesions in the nasal cavity, received in the department of pathology. The age and sex of the patients were recorded. The tissues were routinely processed for histopathologic sections and stained with haematoxylin and eosin stains. Special stains like Periodic acid Schiff (PAS) was done wherever applicable. The cases were classified into neoplastic and nonneoplastic lesions. The neoplastic lesions were further classified according to WHO classification on histopathologic examination. Results: Analysis of 100 polypoidal lesions in the nose and paranasal sinuses with clinical diagnosis of nasal polyps, revealed 66 cases were nonneoplastic and 34 were neoplastic;17 (50%)were benign and 17(50%) were malignant. True nasal polyps both inflammatory and allergic together comprised 44 cases of the 100 polypoidal lesions in the nasal cavity. Angiofibroma and inverted papilloma were the most frequent benign tumour accounting for 12/17(0.7%). The most common malignant tumour was anaplastic carcinoma 7/17(0.4%). Nonneoplastic and benign tumours were common in younger age groups whereas malignant tumours were most common in older males. Conclusion: The majority of polypoidal lesions in the nasal cavity are nonneoplastic. PMID:23905098

Kumari M K, Kalpana; K C, Mahadeva

2013-06-01

349

Oral Lesions in Kidney Transplant Patients  

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Full Text Available Introduction. Oral hygiene in kidney transplant recipients contributes to maintenance of the transplanted organ and its function. Thus, an investigation of oral lesions could be counted as a notable work. These patients have the potential to be involved with lesions developed as a result of the administration of immunosuppressive drugs. The aim of this study was to investigate oral lesions in a group of kidney transplant recipients.Materials and Methods. The present study was a cross-sectional research on 100 patients with a kidney transplant for at least 3 months. Oral mucosa was assessed clinically for any lesion. Additional data on systemic diseases, transplant duration, and medications were recorded.Results. Twenty-four percent of the patients had at least 1 oral lesion. The most common lesion was oral candidiasis in 16% of the participants (13 cases of acute pseudomembranous and 3 cases of chronic oral candidiasis. Gingival enlargement was seen in 7% of the kidney transplant recipients, and 2% had a coated tongue.Conclusions. Elimination of oral fungal lesions in kidney transplant recipients is highly recommended. We hope this study can shed light on this particular aspect of healthcare in kidney transplant recipients.

Mahnaz Sahebjamee

2010-07-01

350

Diagnosis of cerebral lesions by thallium-201  

International Nuclear Information System (INIS)

The authors describe the diagnostic possibilities of Thallium-201 in cerebral lesions of various kinds. Two radiopharmaceuticals were used in 124 patients: thallium-201 citrate and technetium-99m pertechnetate. When 201Tl was used, all cases of definite cerebral lesion gave a positive result within 10 minutes of injection. In 85.4 percent the definition was better, and small metastases which were invisible with /sup 99m/Tc could be demonstrated. More than two-thirds of the time, neoplastic lesions were better defined and distinguished from adjacent normal areas of hyperactivity. Thallium-201 promises greater diagnostic usefulness with an examination time of only 30 minutes

1978-01-01

351

Primary and secondary brain stem lesions  

Energy Technology Data Exchange (ETDEWEB)

This volume is the first to describe all clinically and experimental relevant aspects of primary and secondary brain stem lesions. It contains a detailed description of the computer-tomographical and morphological changes of the cerebral cisterns in acutely and chronically increased intracranial pressure. The prognostic value of clinical parameters of primary and secondary brain stem lesions is demonstrated. The possibilities of assessing the clinical course by computer-aided evaluation are presented. In addition to that, comprehensive view of morphological, radiological and clinical findings, extensive investigation concerning blink reflex (BR) and auditory evoked brain stem potentials (BAEP) supply high relevant functional aspects of those lesions.

Csecsei, G.; Hoffmann, O.; Klug, N.; Laun, A.; Schonmayr, R.

1987-01-01

352

Acquired CNS lesions in fetal MRI  

International Nuclear Information System (INIS)

Acquired central nervous system (CNS) lesions are often subtle; therefore, the prenatal diagnosis of these lesions is extremely important. The fetal ultrasound examination and magnetic resonance imaging (MRI) are two important imaging methods that give an insight into these types lesions. The method of choice during pregnancy is still fetal ultrasound; however, fetal MRI is important when there are certain pathologies, e.g. periventricular leukomalacia (PVL) or malformations of the vein of Galen. In this manner clinicians can plan further therapy after childbirth in advance (e.g. cerebral angiography or embolization). (orig.)

2013-02-01

353

FDG-PET in infectious lesions. The detection and assessment of lesion activity  

International Nuclear Information System (INIS)

The usefulness of FDG-PET in the detection of infectious foci and the assessment of lesion activity was evaluated. The study covered 24 patients with 25 FDG-PET studies, including lesions of bacterial, tuberculous and fungal origins. The FDG uptake was determined by the lesion to muscle ratio (LMR) on the static images. The time activity curves (TACs) were classified into four patterns based on both the existence of an initial peak and a slope thereafter. A high FDG uptake was observed in 23 of 25 lesions (92%). Two lesions, in which no abnormal uptake was noted, included one in the healing stage and the other consisting of a cavity with a thin wall. The acute active lesions showed higher LMRs than the chronic active or healing lesions (mean±SD: 9.8±3.6, 3.6±1.8 and 4.3±1.7, respectively, p<0.05), and they could be approximately distinguished by an LMR of 6. The patterns of the TACs in acute or chronic active lesions were either an increase without an initial peak or a plateau, while those in the healing lesions demonstrated predominantly an increase with an initial sharp peak. Our results indicated that FDG-PET is clinically useful in the detection of the infection of miscellaneous microorganisms as well as in the assessment of lesion activity. (author)

1996-05-01

354

FDG-PET in infectious lesions. The detection and assessment of lesion activity  

Energy Technology Data Exchange (ETDEWEB)

The usefulness of FDG-PET in the detection of infectious foci and the assessment of lesion activity was evaluated. The study covered 24 patients with 25 FDG-PET studies, including lesions of bacterial, tuberculous and fungal origins. The FDG uptake was determined by the lesion to muscle ratio (LMR) on the static images. The time activity curves (TACs) were classified into four patterns based on both the existence of an initial peak and a slope thereafter. A high FDG uptake was observed in 23 of 25 lesions (92%). Two lesions, in which no abnormal uptake was noted, included one in the healing stage and the other consisting of a cavity with a thin wall. The acute active lesions showed higher LMRs than the chronic active or healing lesions (mean{+-}SD: 9.8{+-}3.6, 3.6{+-}1.8 and 4.3{+-}1.7, respectively, p<0.05), and they could be approximately distinguished by an LMR of 6. The patterns of the TACs in acute or chronic active lesions were either an increase without an initial peak or a plateau, while those in the healing lesions demonstrated predominantly an increase with an initial sharp peak. Our results indicated that FDG-PET is clinically useful in the detection of the infection of miscellaneous microorganisms as well as in the assessment of lesion activity. (author)

Ichiya, Yuichi; Kuwabara, Yasuo; Sasaki, Masayuki; Yoshida, Tsuyoshi; Akashi, Yuko; Murayama, Sadayuki; Nakamura, Katsumasa; Fukumura, Toshimitsu; Masuda, Kouji [Kyushu Univ., Fukuoka (Japan). Faculty of Medicine

1996-05-01

355

Approximate Lesion Localization in Dermoscopy Images  

CERN Multimedia

Background: Dermoscopy is one of the major imaging modalities used in the diagnosis of melanoma and other pigmented skin lesions. Due to the difficulty and subjectivity of human interpretation, automated analysis of dermoscopy images has become an important research area. Border detection is often the first step in this analysis. Methods: In this article, we present an approximate lesion localization method that serves as a preprocessing step for detecting borders in dermoscopy images. In this method, first the black frame around the image is removed using an iterative algorithm. The approximate location of the lesion is then determined using an ensemble of thresholding algorithms. Results: The method is tested on a set of 428 dermoscopy images. The localization error is quantified by a metric that uses dermatologist determined borders as the ground truth. Conclusion: The results demonstrate that the method presented here achieves both fast and accurate localization of lesions in dermoscopy images.

Celebi, M Emre; Schaefer, Gerald; Stoecker, William V; 10.1111/j.1600-0846.2009.00357.x

2010-01-01

356

Imaging of the cavernous sinus lesions.  

Science.gov (United States)

This educational paper reviews the normal anatomy of the cavernous sinus (CS) and the imaging findings of common and uncommon lesions of this region. CS lesions may arise from different components of the CS or from adjacent structures and spaces. They can be classified as tumoral, inflammatory/infectious, vascular and congenital. Tumoral lesions include benign (meningiomas, pituitary adenomas, schwannomas) and malignant neoplasms (chondrosarcomas, chordomas, nasopharyngeal carcinomas, leukemia, metastases). Inflammatory/infectious conditions comprise: Tolosa Hunt, abscess, Lemierre syndrome and thrombophlebitis. Vascular lesions include: hemangiomas, carotido-cavernous fistula, aneurysms, arteriovenous malformations. Congenital conditions include the epidermoid cyst, dermoid cyst and fatty deposits. Although imaging features of non-vascular CS diseases are most often non-specific, careful analysis of the adjacent structures suggests the correct diagnosis. In vascular pathology, characteristic MR imaging findings are observed. PMID:23763988

Korchi, A M; Cuvinciuc, V; Caetano, J; Becker, M; Lovblad, K O; Vargas, M I

2013-06-10

357

Pyogenic granuloma with multiple and satellite lesions  

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Full Text Available Pyogenic granuloma is a benign vascular tumour of the skin or mucosa. We report two patients of pyogenic granuloma with spontaneous occurrence of multiple and satellite lesions, a rare occurrence.

Sethuraman Gomathy

2006-01-01

358

Ulcerative colitis complicated by gastroduodenal lesions.  

Science.gov (United States)

A case of ulcerative colitis complicated with gastric and duodenal lesions is reported. The patient was a 17-year-old male who was admitted with bloody diarrhea and abdominal pain. Based on the endoscopic and histological findings of the colon, a diagnosis of ulcerative colitis was made. Upper gastrointestinal endoscopy showed multiple erosions and granular changes in the antral greater curvature of the stomach and descending portion of the duodenum. Histological examination of the stomach and duodenum revealed marked inflammatory cell infiltration and crypt abscesses. Clinically, the gastric and duodenal lesions did not respond to antiulcer drugs, but were alleviated by steroid. It was concluded that the pathogenesis of the gastric and duodenal lesions in this patient was similar to that of the colonic lesions of ulcerative colitis. PMID:8844483

Sasaki, M; Okada, K; Koyama, S; Yoshioka, U; Inoue, H; Fujiyama, Y; Bamba, T

1996-08-01

359

Traumatic vascular lesions. Radiological diagnosis - therapeutic consequences  

Energy Technology Data Exchange (ETDEWEB)

Based on experience with 166 traumatic vascular lesions in 148 patients, the authors present the diagnostic methods and therapeutic consequences, which are at the moment applied at the Medical Highschool Hannover.

Hendrickx, P.; Luska, G.; Stegmann, T.; Oestern, H.J.; Schindler, E.; Becker, H.

1985-06-01

360

CT evaluation of right colonic wall lesions  

International Nuclear Information System (INIS)

CT of the entire clean colon after a tap water enema with intravenous injection of contrast medium was performed in 20 patients with a diagnosis of caecal and ascending colonic lesions at barium enema studies or colonoscopy. Histological proof was obtained by endoscopy or at surgery in all cases. Using this ''water technique'' we were able to detect the wall abnormalities and describe their CT features in relation to the histological findings. We found that asymmetric thickening of the bowel wall, an irregular and lobulated inner and outer contour and/or a focal soft tissue mass usually exceeding 2 cm from the luminal to serosal surface were very helpful findings for a malignant lesion but not the hallmark of malignancy. The CT appearance of the extraluminal part of the lesion was most helpful in differentiating between benign and malignant lesions. (orig.)

1994-08-01

 
 
 
 
361

Morphometry and Variations of Bony Ponticles of the Atlas Vertebrae (C1 in Kenyans Morfometría y Variaciones de Puentes Óseos de la Vértebra Atlas (C1 en Kenianos  

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Full Text Available Atlas bridges, the bony outgrowths over the third segment of the vertebral artery are associated with compression of the artery and nerves. There are limited studies comparing morphometry of the complete atlas bridges and that of the ipsilateral transverse foramen. Bilateral and gender differences in the morphometry of the complete bridges remain relatively unexplored. One hundred and two atlas vertebrae (49 male and 53 female obtained from the Osteology Department of the National Museums of Kenya were used for this study. The presence of complete posterior atlas bridge (retroarticular canal and lateral bridge (supratransverse foramen was noted. Measurements were taken for the diameters of foramina, and the ipsilateral transverse foramina and their areas calculated. Complete posterior bridges occurred in 14.6% and 13.6% on the right and left sides respectively. The lateral bridge was found in 3.9% of the cases on the right side only. The complete posterior bridges had a cross-sectional area of 23.44mm2 on the right and 24.98mm2 on the left side. The lateral bridges had a mean cross-sectional area of 27.30mm2. The right and left transverse foramina had mean crosssectional area of 36.30mm2 and 37.20mm2 respectively, which was significantly larger than that of the ipsilateral complete and posterior bridges. The smaller dimensions of the complete atlas bridges compared to the ipsilateral transverse foramen suggest that they may predispose to vertebrobasilar insufficiency, Barre-Lieou and cervicogenic syndromes due to compression of the contents in the foramina.Puentes del atlas, sobrecrecimientos óseos en el tercer segmento de la arteria vertebral se asocian con la compresión de la arteria y los nervios. Hay pocos estudios que comparan la morfometría de los puentes completos del atlas y el foramen transversal ipsilateral. Diferencias bilaterales y de género en la morfometría de los puentes completos permanecen relativamente inexplorados. Ciento dos vértebras atlas (49 hombres y 53 mujeres obtenidos del Departamento de Osteología de los Museos Nacionales de Kenya se utilizaron para este estudio. Fueron identificados la presencia de puentes completos posteriores del atlas (canal retroarticular y puentes laterales (foramen supratransverso. Se realizaron las mediciones de los diámetros del foramen y los forámenes transversos ipsilaterales, y se calcularon sus áreas. Puentes completos posteriores se observaron en el 14,6% y 13,6% de los lados derecho e izquierdo, respectivamente. El puente lateral se encontró en el 3,9% de los casos en el lado derecho solamente. Los puentes completos posteriores tuvieron un área transversal de 23,44mm2 en el lado derecho y 24,98mm2 en el lado izquierdo. Los puentes laterales tuvieron un área media de sección transversal de 27,30mm2. En los lados derecho e izquierdo se encontrron forámenes transversos con un área promedio de sección transversal de 36,30mm2 y 37,20mm2 respectivamente, lo que fue significativamente mayor que el de los puentes completos ipsilaterales y posteriores. Las dimensiones más pequeñas de los puentes atlas completos en comparación con los forámenes transversos ipsilaterales sugieren que pueden predisponer a la insuficiencia vertebrobasilar, síndromes de Barre-Lieou y cervical debido a la compresión de los contenidos en los forámenes.

P Karau Bundi

2010-12-01

362

Morphometry and Variations of Bony Ponticles of the Atlas Vertebrae (C1) in Kenyans / Morfometría y Variaciones de Puentes Óseos de la Vértebra Atlas (C1) en Kenianos  

Scientific Electronic Library Online (English)

Full Text Available SciELO Chile | Language: English Abstract in spanish Puentes del atlas, sobrecrecimientos óseos en el tercer segmento de la arteria vertebral se asocian con la compresión de la arteria y los nervios. Hay pocos estudios que comparan la morfometría de los puentes completos del atlas y el foramen transversal ipsilateral. Diferencias bilaterales y de géne [...] ro en la morfometría de los puentes completos permanecen relativamente inexplorados. Ciento dos vértebras atlas (49 hombres y 53 mujeres) obtenidos del Departamento de Osteología de los Museos Nacionales de Kenya se utilizaron para este estudio. Fueron identificados la presencia de puentes completos posteriores del atlas (canal retroarticular) y puentes laterales (foramen supratransverso). Se realizaron las mediciones de los diámetros del foramen y los forámenes transversos ipsilaterales, y se calcularon sus áreas. Puentes completos posteriores se observaron en el 14,6% y 13,6% de los lados derecho e izquierdo, respectivamente. El puente lateral se encontró en el 3,9% de los casos en el lado derecho solamente. Los puentes completos posteriores tuvieron un área transversal de 23,44mm2 en el lado derecho y 24,98mm2 en el lado izquierdo. Los puentes laterales tuvieron un área media de sección transversal de 27,30mm2. En los lados derecho e izquierdo se encontrron forámenes transversos con un área promedio de sección transversal de 36,30mm2 y 37,20mm2 respectivamente, lo que fue significativamente mayor que el de los puentes completos ipsilaterales y posteriores. Las dimensiones más pequeñas de los puentes atlas completos en comparación con los forámenes transversos ipsilaterales sugieren que pueden predisponer a la insuficiencia vertebrobasilar, síndromes de Barre-Lieou y cervical debido a la compresión de los contenidos en los forámenes. Abstract in english Atlas bridges, the bony outgrowths over the third segment of the vertebral artery are associated with compression of the artery and nerves. There are limited studies comparing morphometry of the complete atlas bridges and that of the ipsilateral transverse foramen. Bilateral and gender differences i [...] n the morphometry of the complete bridges remain relatively unexplored. One hundred and two atlas vertebrae (49 male and 53 female) obtained from the Osteology Department of the National Museums of Kenya were used for this study. The presence of complete posterior atlas bridge (retroarticular canal) and lateral bridge (supratransverse foramen) was noted. Measurements were taken for the diameters of foramina, and the ipsilateral transverse foramina and their areas calculated. Complete posterior bridges occurred in 14.6% and 13.6% on the right and left sides respectively. The lateral bridge was found in 3.9% of the cases on the right side only. The complete posterior bridges had a cross-sectional area of 23.44mm2 on the right and 24.98mm2 on the left side. The lateral bridges had a mean cross-sectional area of 27.30mm2. The right and left transverse foramina had mean crosssectional area of 36.30mm2 and 37.20mm2 respectively, which was significantly larger than that of the ipsilateral complete and posterior bridges. The smaller dimensions of the complete atlas bridges compared to the ipsilateral transverse foramen suggest that they may predispose to vertebrobasilar insufficiency, Barre-Lieou and cervicogenic syndromes due to compression of the contents in the foramina.

P, Karau Bundi; J. A, Ogeng´o; J, Hassanali; P. O, Odula.

363

Lesiones proliferativas más frecuentes del complejo bucomaxilofacial / Most frequent proliferative lesions of the Buco Maxillofacial Complex  

Scientific Electronic Library Online (English)

Full Text Available SciELO Cuba | Language: Spanish Abstract in spanish Introducción: las lesiones proliferativas son entidades que se presentan en la cavidad bucal. Algunas son de origen traumático y otras son neoplasias. Con frecuencia no son bien diagnosticadas en la clínica, por la similitud que pueden presentarse entre ellas. Objetivo: determinar las característica [...] s de las lesiones proliferativas diagnosticadas y la coincidencia entre el diagnóstico clínico y el histopatológico. Método: se realizó un estudio retrospectivo de las biopsias procesadas en cinco años en el Departamento de Patología de la Facultad de Estomatología de La Habana atendiendo a edad y sexo del paciente, tipo de lesión, localización anatómica y coincidencia entre el diagnóstico clínico y el histopatológico. Resultados: se encontró que de las lesiones proliferativas, las pseudotumorales aportaron el 18,1 % y las neoplasias benignas el 5,8 %. En el grupo de edad de 10 a 19 años las lesiones pseudotumorales representaron el 7,78 % y las neoplasias benignas el 1,78 %. En el grupo de 60 años o más, las lesiones pseudotumorales aportaron el 22,67 % del total de lesiones proliferativas. El sexo femenino resultó afectado por lesiones pseudotumorales en 61,3 % y las neoplasias benignas afectaron al sexo masculino en un 55 %. La hiperplasia fibroepitelial representó el 54,22 % de las pseudotumorales, mientras que el nevus aportó el 8,67 % entre las neoplasias benignas. Los diagnósticos clínicos de las lesiones pseudotumorales coincidieron en un 50,4 % con los histológicos, para las neoplasias benignas la coincidencia fue del 53,2 %. Conclusiones: las lesiones pseudotumorales predominaron sobre las neoplasias benignas, con un incremento marcado de ambos tipos de lesiones a partir de los 40 años. En el sexo femenino predominaron las lesiones pseudotumorales, y en el masculino predominaron las neoplasias benignas. Se encontró una baja coincidencia entre el diagnóstico clínico e histopatológico para ambos tipos de lesiones. Abstract in english Introduction: proliferative lesions are entities that are present in the buccal cavity. Some of them are of traumatic origin and others are neoplasias. Frequently, they are not well diagnosed in the clinical practice because of the similarity that can exist among them. Objective: to determine the ch [...] aracteristics of the proliferative lesions diagnosed and the coincidences between clinical and histopathological diagnosis Method: a retrospective study of the biopsies processed during five years in the Department of Oral Pathology of the Faculty of Stomatology of Havana was conducted dealing with age, sex, type of lesion, anatomic location and similarities between the clinical and histopathological diagnosis. Results: it was found that, of the proliferative lesions, the pseudotumoral ones reported the 18.1 % and the benign neoplasias, the 5.8 %. In the age group 10-19 years, pseudotumoral lesions represented the 7.78 % and the benign neoplasias the 1,78 %. In the group of 60 years or older, pseudotumoral lesions reported the 22.67 % of the total of proliferative lesions. The female sex resulted to be affected by pseudotumoral lesions in a 61,3 % and the benign neoplasias effected the male sex in a 55 %. Fibroepithelial hyperplasia represented the 54.22 % of the pseudotumoral ones, whereas the nevus reported the 8.67 % among the benign neoplasias. The clinical diagnosis of the pseudotumoral lesions matched up a 50.4 % with the histological; for benign neoplasias, the coincidence was 53.2 %. Conclusions: pseudotumoural lesions predominated on benign neoplasias, with a marked increase in both types of lesions after 40 years. Pseudotumoural lesions predominated in the female sex, whereas the benign neoplasias predominated in the male sex. There was a low coincidence between the clinical and histopathological diagnosis for both types of lesions.

Barceló López, Katia; Delgado Fernández, Rafael; Rodríguez Soto, Agustín.

364

Focal lesions in the central nervous system  

International Nuclear Information System (INIS)

This report reviews the animal and human studies currently in progress at LBL with heavy-ion beams to induce focal lesions in the central nervous system, and discusses the potential future prospects of fundamental and applied brain research with heavy-ion beams. Methods are being developed for producing discrete focal lesions in the central nervous system using the Bragg ionization peak to investigate nerve pathways and neuroendocrine responses, and for treating pathological disorders of the brain

1980-11-01

365

Cystic lesions of the seminal vesicles  

International Nuclear Information System (INIS)

Between October 1990 and March 1991, 8 patients with cystic lesions in the region of the posterior bladder wall, the seminal vesicles and the prostate were examined by MRI. In all cases there was accurate characterisation of the lesion and of its anatomy. In 3 patients with abnormalities in the retrovesical space there was very good agreement with the operative findings. 4 patients were treated conservatively. In these patients there was good agreement with the findings on cystoscopy, CT and sonography. (orig.)

1992-07-01

366

Angiocentric Lesions of the Head and Neck  

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Angiocentric lesions of the head and neck encompass a variety of benign and malignant lesions. Not unexpectedly the sequelae of an angiocentric process independent of its benign or malignant nature is one of tissue ischemia with a potential for either breakdown or reparative fibrosis. Therefore, the clinical presentations can be very similar despite a varied pathogenesis. Among the benign reactive infiltrates that will be considered are angiocentric eosinophilic fibrosis, Wegener’s granulom...

2008-01-01

367

Detection of Treponema denticola in Atherosclerotic Lesions  

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We examined 26 atherosclerotic lesions and 14 nondiseased aorta specimens to detect the periodontopathogenic part of the bacterial 16S rRNA locus by PCR. Treponema denticola sequence of the 16S rRNA locus was found in 6 out of 26 DNA samples (23.1%) from the formalin-fixed, paraffin-embeded atherosclerotic lesions obtained during surgery but not in any of the 14 nondiseased aorta samples from deceased persons. Utilizing immunofluorescence microscopy, we observed aggregated antigenic particles...

2001-01-01

368

A clinicopathologic study of excised conjunctival lesions  

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Purpose : This study was aimed at to determine the frequency of excised conjunctival lesions in a patient population treated over a 10-year period. Materials and Methods : The data of all excised conjunctival lesions with tissue diagnoses from 1998 to 2008 in the pathology department were analyzed. Results : The patient group comprised 192 conjunctival specimens; 106 (55.2%) obtained from male patients and 86 (44.8 %) from female patients. The age range wa...

Mohamad Elshazly Laila

2011-01-01

369

Polypoid uterine lesions mimicking endometrial stromal sarcoma.  

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Two polypoid submucosal uterine lesions were examined histologically and immunohistochemically with monoclonal antibodies to desmin and alpha smooth muscle actin. One case comprised a leiomyoma and the other a polypoid form of adenomyosis. Both polyps had prolapsed through the external cervical os. The lesions had an ulcerated surface with focal areas of marked increased cellularity and pronounced vascularity throughout, such that they mimicked a low grade endometrial stromal sarcoma infiltra...

Mccluggage, W. G.; Alderdice, J. M.; Walsh, M. Y.

1999-01-01

370

Method of diagnosis of immunocomplex pulmonary lesions  

International Nuclear Information System (INIS)

To improve the accuracy of diagnosis a method of diagnosis of immunocomplex pulmonary lesions is proposed. The method lies in the following: after roentgenography of the lungs prednisolone is injected during a week and then roentgenography of the lungs is repeated, and when the pulmonary pattern has changed to normalization, the diagnosis of immunocomplex pulmonary lesions is stated. An illustration is given how to use the proposed method of diagnosis decreasing the diagnosis time twice and improving the accuracy of diagnosis

1984-01-01

371

Supraorbital eyebrow approach to skull base lesions  

Directory of Open Access Journals (Sweden)

Full Text Available We report our experience with a supraorbital eyebrow minicraniotomy. This technique is suitable to lesions situated in the region of the anterior fossa, suprasellar cisterns, parasellar region and Sylvian fissure. A 50 mm incision in the eyebrow and a supraorbital minicraniotomy is performed. Sixteem patients harboring different lesions were operated on with good postoperative and cosmetic results. We conclude that this approach is safe and useful in selected cases.

Fernandes Yvens Barbosa

2002-01-01

372

Amnesia after a discrete basal forebrain lesion  

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Destructive lesions of the basal forebrain are often associated with memory impairment and this structure is thought to contribute to memory function by providing a cholinergic input to critical structures associated with memory such as the hippocampus and amygdala. In previously reported cases of amnesia associated with damage in the basal forebrain, multiple neuroanatomical regions were damaged, and the critical lesion responsible for amnesia has not been identified cle...

Abe, K.; Inokawa, M.; Kashiwagi, A.; Yanagihara, T.

1998-01-01

373

Percutaneous acetabuloplasty for metastatic acetabular lesions  

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Abstract Background Osteolytic metastases around the acetabulum are frequent in tumour patients, and may cause intense and drug-resistant pain of the hip. These lesions also cause structural weakening of the pelvis, limping, and poor quality of life. Percutaneous acetabuloplasty is a mini-invasive procedure for the management of metastatic lesions due to carcinoma of the acetabulum performed in patients who cannot tolerate major surgery, or in patients towards whom radiothera...

Maccauro Giulio; Liuzza Francesco; Scaramuzzo Laura; Milani Alessandro; Muratori Francesco; Rossi Barbara; Waide Victor; Logroscino Giandomenico; Logroscino Carlo A; Maffulli Nicola

2008-01-01

374

Lesions in the external auditory canal  

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The external auditory canal is an S- shaped osseo-cartilaginous structure that extends from the auricle to the tympanic membrane. Congenital, inflammatory, neoplastic, and traumatic lesions can affect the EAC. High-resolution CT is well suited for the evaluation of the temporal bone, which has a complex anatomy with multiple small structures. In this study, we describe the various lesions affecting the EAC.

Chatra, Priyank S.

2011-01-01

375

Petrous apex lesions outcome in 21 cases  

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Petrous apex lesions of temporal bone progress slowly. Most of the time not only destruct this area but also involve neighbouring element. The symptoms of the neighbouring neuro-vasculare involvement we can recognize these lesions. The most common symptoms of involvement of the petrous apex are: headache, conductive hearing loss or sensorineural type, paresthesia and anesthesia of the trigeminal nerve, paresia and paralysis of the facial nerve, abducent nerve. In retrospective study which has...

Hekmatara M

1997-01-01

376

Computerized lesion detection on breast ultrasound  

International Nuclear Information System (INIS)

We investigated the use of a radial gradient index (RGI) filtering technique to automatically detect lesions on breast ultrasound. After initial RGI filtering, a sensitivity of 87% at 0.76 false-positive detections per image was obtained on a database of 400 patients (757 images). Next, lesion candidates were segmented from the background by maximizing an average radial gradient (ARD) index for regions grown from the detected points. At an overlap of 0.4 with a radiologist lesion outline, 75% of the lesions were correctly detected. Subsequently, round robin analysis was used to assess the quality of the classification of lesion candidates into actual lesions and false-positives by a Bayesian neural network. The round robin analysis yielded an Az value of 0.84, and an overall performance by case of 94% sensitivity at 0.48 false-positives per image. Use of computerized analysis of breast sonograms may ultimately facilitate the use of sonography in breast cancer screening programs

2002-07-01

377

Lesion load in unprotected carotid artery stenting  

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The purpose of the study was to determine the incidence of new ischemic lesions found on diffusion-weighted MR imaging (DWI) in nonselected patients after unprotected carotid artery stent placement. We retrospectively reviewed a nonrandomized cohort of 197 patients presenting with carotid occlusive disease who underwent unprotected carotid artery stent placement between 2003 and 2006. Mean degree of stenosis was 86.94% {+-} 9.72. In all patients, DWI was obtained before and 24 h after stent placement. New lesions were evaluated according to size and location. In 59 of 197 patients (29.9%), new ischemic lesions were found on DWI in the vessel dependent area. In 23 of 197 patients (11.7%), new ischemic lesions were found in the vessel independent area. Combined stroke/death rate was 3.63%. In our series of unprotected carotid angioplasty with stent, we found new DWI lesions in 34% of the patients. Further studies should now show in how far protection devices can reduce these lesions. (orig.)

Grunwald, I.Q.; Papanagiotou, P.; Roth, C.; Karp, K.; Krick, C.; Schieber, H.; Mueller, M.; Reith, W. [University of the Saarland, Department for Diagnostic and Interventional Neuroradiology, Homburg (Germany); Fassbender, K.; Haass, A. [University of the Saarland, Division of Neurology, Homburg (Germany)

2009-05-15

378

Masticator space lesions: MRI and CT findings  

International Nuclear Information System (INIS)

We evaluated the MR and CT findings of the masticator space lesions in order to identify the differences among the malignant and benign tumors and infectious conditions. MR and CT findings in 46 cases with proven masticator space lesions were reviewed retrospectively. We analysed the involvement of masticator muscles, adjacent spaces, orbit and intracranium, homogeneity, necrosis, cystic changes, growth patterns, calcifications, enhancement patterns, MR signal intensity, and CT attenuation. Among the 29 cases of malignant tumors, seven cases were mandibular tumors including four chondrosarcomas, and 22 cases were extramandibular tumors. Malignant tumors of mandibular origin showed large masses with severe bone destruction and epicenter of mandible. Extramandibular malignant tumors showed the epicenter out of the mandible and less severe bone destruction than mandibular tumors. Among the nine benign tumors, four cases were ameloblastomas which showed the well-defined masses and the expansion of the mandible, and four cases were extramandibular tumors which showed well-marginated extramandibular masses with no bone destruction. Among the eight infectious conditions, five cases were mandibular osteomyelitis with or without abscess formations, and the other three cases were infections from adjacent soft tissue or limited to the soft tissue. By careful observations of growth patterns, involvement of the masticator and adjacent spaces, bone changes, and epicenter of the lesions, one can discriminate a mandibular lesion from an extramandibular lesion. With this approach, it is thought to be easier to suggest a diagnosis among a wide spectrum of masticator lesions

1995-02-01

379

Texture feature based liver lesion classification  

Science.gov (United States)

Liver lesion classification is a difficult clinical task. Computerized analysis can support clinical workflow by enabling more objective and reproducible evaluation. In this paper, we evaluate the contribution of several types of texture features for a computer-aided diagnostic (CAD) system which automatically classifies liver lesions from CT images. Based on the assumption that liver lesions of various classes differ in their texture characteristics, a variety of texture features were examined as lesion descriptors. Although texture features are often used for this task, there is currently a lack of detailed research focusing on the comparison across different texture features, or their combinations, on a given dataset. In this work we investigated the performance of Gray Level Co-occurrence Matrix (GLCM), Local Binary Patterns (LBP), Gabor, gray level intensity values and Gabor-based LBP (GLBP), where the features are obtained from a given lesion`s region of interest (ROI). For the classification module, SVM and KNN classifiers were examined. Using a single type of texture feature, best result of 91% accuracy, was obtained with Gabor filtering and SVM classification. Combination of Gabor, LBP and Intensity features improved the results to a final accuracy of 97%.

Doron, Yeela; Mayer-Wolf, Nitzan; Diamant, Idit; Greenspan, Hayit

2014-03-01

380

Bony pathologies of the metacarpophalangeal joints in early rheumatoid arthritis. Comparison of MRI and high-resolution SPECT; Knoecherne Pathologien der Metacarpophalangeal-Gelenke bei frueher rheumatoider Arthritis. Vergleich zwischen MRT und hochaufloesender SPECT  

Energy Technology Data Exchange (ETDEWEB)

Aim: comparison of MRI with a newly developed high-resolution multi-pinhole single photon emission computed tomography (MPH-SPECT) regarding the detection of bony pathologies of the metacarpophalangeal (MCP) joints in patients with early rheumatoid arthritis (ERA). Materials and methods: the clinically dominant hand of 15 patients with ERA (disease duration 6 months) was examined using MRI and MPH-SPECT. The evaluation of MRI was achieved according to RAMRIS criteria and for the MPH SPECT regarding pathological tracer uptake and distribution. Image fusions of MRI and MPH-SPECT were provided and the two methods were compared. Results: in MRI 12 of 15 patients showed arthritic joint pathologies, while 8 patients exhibited soft tissue and bony changes. 4 patients had only soft tissue inflammation (synovitis) with a normal bone signal. In MPH-SPECT 10 of 15 patients showed pathologically increased bone metabolism. The fusion images presented a high agreement of the pathological changes in both methods, while areas with increased bone metabolism were not only present in the case of erosions, but also in the case of bone edema. In 2 patients increased bone metabolism was detectable in areas of MR tomographic normal bone, while a clear surrounding synovitis was present in each case here. (orig.)

Scherer, Axel; Blondin, D.; Reichelt, D.; Moedder, U. [Radiologie, Heinrich-Heine Univ., Duesseldorf (Germany); Wirrwar, A.; Mattes-Gyoergy, K.; Mueller, H.W. [Nuklearmedizin, Heinrich-Heine Univ., Duesseldorf (Germany); Schneider, M. [Rheumatologie, Klinik fuer Endokrinologie, Diabetologie und Rheumatologie, Heinrich-Heine Univ., Duesseldorf (Germany); Ostendorf, B. [Radiologie, Heinrich-Heine Univ., Duesseldorf (Germany); Rheumatologie, Klinik fuer Endokrinologie, Diabetologie und Rheumatologie, Heinrich-Heine Univ., Duesseldorf (Germany)

2009-09-15

 
 
 
 
381

Extensión del límite austral de distribución de tres especies de peces óseos tropicales en la costa de la Provincia de Buenos Aires, Argentina Southern extension of three species of tropical bony fishes along the coast of Buenos Aires Province, Argentina  

Directory of Open Access Journals (Sweden)

Full Text Available Se presentan tres nuevos registros de especies de peces óseos cuya distribución corresponde a aguas tropicales, capturados por buques pesqueros en la costa de la Provincia de Buenos Aires, Argentina (CPBA, 36°-38°S. Los ejemplares corresponden a las especies: Rachycentrum canadum, Elops saurus y Caulolatilus chrysops. Estos registros amplían significativamente el límite austral de su distribución. La presencia ocasional de estas especies está asociada al transporte de agua subtropical cálida proveniente de la plataforma continental brasilera. Esta hipótesis es probada mediante el análisis de imágenes satelitales de temperatura superficial del mar.We document the southern records of three species of tropical bony fishes along the coast of Buenos Aires Province, Argentina (CBAP, 36-38°S. Rachycentrum canadum, Elops saurus and Caulolatilus chrysops were caught by bottom-trawl commercial vessels. Records presented here significantly extend southward their latitudinal distribution from those previously reported. Using sea surface temperature satellite images we show a southward warm circulation event from Brazil as a putative factor to explain the occurrence of these bony fishes in the CBAP.

Andrés C Milessi

2012-11-01

382

Benign breast lesions in Eastern Nigeria  

International Nuclear Information System (INIS)

Objective was to characterize benign breast diseases in Eastern Nigeria and to highlight the age variations of these lesions as base line data. The Department of Morbid Anatomy, University of Nigeria Teaching Hospital, Enugu caters for over 30 million African blacks and receives 2000 surgical pathology specimens yearly. Seven hundred and twenty-two benign breast specimens were analyzed over 5 years from Ist January 2000 to 31 December 2004, out of 1050 breast samples received. Of 1050 breast specimens received, 722 (68.8%) were benign. Fibroadenoma was the most common lesion with 318 cases (44%), occurring at a mean age of 16-32 years. Next were fibrocystic changes with 165 cases (22.9%) at a mean age of 23-45 years. Normal breast in the axillary tail region was seen in 32 cases (4.4%), represented as no pathology, with a mean presentation age of 20-46 years. Low grade Phyllodes tumor had 28 cases (3.9%), presenting at an average mean age of 17-32 years. Lactating adenoma had 19 (2.6%) cases. Other lesions made up less than 3% each. Benign breast lesions peaked at the 20-24 age range and then declined. Most were females. Benign breast lesions occur more frequently than malignant breast lesions with a ratio of 2.3:1 and were presented 20 years earlier than their malignant counterparts. Fibroadenoma was the most common benign lesions followed by fibrocystic disease, similar to the findings in Western Nigeria. In Northern Nigeria, fibrocystic breast disease was more common. (author)

2004-12-31

383

Lesiones intraorales de glándulas salivales menores Intraoral lesions of minor salivary glands. Analysis of 59 patients  

Directory of Open Access Journals (Sweden)

Full Text Available Introducción: Las lesiones de glándulas salivales menores son en su mayoría benignas. Los tumores son infrecuentes y conforman un grupo heterogéneo, siendo el adenoma pleomorfo Ia neoplasia benigna más frecuente y el carcinoma adenoideo-quistico el tumor maligno más encontrado. Objetivos: El propósito de este estudio es evaluar Ia incidencia, manejo y evolución de Ias lesiones intraorales de glándulas salivales menores en el Servicio de Cirugia de Cabeza y Cuello del Hospital Barros Luco-Trudeau. Material y Método: Se presenta estudio retrospectivo de 59 casos tratados entre 1975 y 2009 en dicho hospital. Resultados: Encontramos 35 mujeres y 24 hombres. En 48 pacientes (81,3% se encontró lesiones benignas, de Ias cuales 35 (73% correspondieron a lesiones no neoplásicas y 13 (27% a neoplasias. Las neoplasias malignas fueron 11 (18,6% del total, 4 (36,3% con Ca mucoepidermoide, 2 (18% con Ca adenoideo-quistico, 2 (18% con Ca de células acinosas, 1 (9% con Ca indiferenciado, 1 (9% con adenocarcinoma y 1 (9% con Ca epider-moide. Conclusiones: Las lesiones de glándulas salivales menores en nuestro hospital se caracterizan por ser predominantemente benignas. Se encontró similar frecuencia de tumores benignos y malignos. Predominó el adenoma pleomorfo entre Ios primeros y el carcinoma mucoepidermoide entre Ios segundos. Los tumores benignos, luego de su extirpación, se manejaron con cierre del lecho tumoral mediante rotación de colgajos locales de mucosa oral para cobertura y, en algunos casos, cierre por segunda intención. La evolución fue en general excelente. En el caso de Ios tumores malignos, el manejo dependió de Ia histología.Background: Most salivary gland lesions are benign. Tumors are uncommon. Pleomorphic adenoma and cystic adenoid carcinoma are the most common benign and malignant lesions. Alm: To assess the incidence management and evolution of intraoral lesions among patients consulting in a head and neck surgical service. Material and Methods: Retrospective review of medical records of patients consulting for intraoral lesions of minor salivary glands between 1975 and 2009 in a head and neck surgical service. Results: Thirty five females and 24 males are reported. Forty eight (81% had benign lesions. Of these, 35 (73%. were non neoplastic lesions. Eleven patients had malignant lesions. Of these, four (36% had a mucoepidermoid carcinoma, two (18% had an adenoid-cystic carcinoma, two (18% had an acinous cell carcinoma and one patient each had an undifferentiated carcinoma, an adenocarcinoma and an epidermoid carcinoma. Conclusions: In this series of patients, benign lesions predominated. Benign lesions were excised and the management of malignant lesions depended on the type of tumor.

MARÍA ANGÉLICA MATAMALA S

2012-08-01

384

Lesiones intraorales de glándulas salivales menores / Intraoral lesions of minor salivary glands. Analysis of 59 patients  

Scientific Electronic Library Online (English)

Full Text Available SciELO Chile | Language: Spanish Abstract in spanish Introducción: Las lesiones de glándulas salivales menores son en su mayoría benignas. Los tumores son infrecuentes y conforman un grupo heterogéneo, siendo el adenoma pleomorfo Ia neoplasia benigna más frecuente y el carcinoma adenoideo-quistico el tumor maligno más encontrado. Objetivos: El propósi [...] to de este estudio es evaluar Ia incidencia, manejo y evolución de Ias lesiones intraorales de glándulas salivales menores en el Servicio de Cirugia de Cabeza y Cuello del Hospital Barros Luco-Trudeau. Material y Método: Se presenta estudio retrospectivo de 59 casos tratados entre 1975 y 2009 en dicho hospital. Resultados: Encontramos 35 mujeres y 24 hombres. En 48 pacientes (81,3%) se encontró lesiones benignas, de Ias cuales 35 (73%) correspondieron a lesiones no neoplásicas y 13 (27%) a neoplasias. Las neoplasias malignas fueron 11 (18,6% del tot