Stevens Johnsons syndrom og toksisk epidermal nekrolyse

DEFF Research Database (Denmark)

Kaur-Knudsen, Diljit; Zachariae, Claus; Thomsen, Simon Francis

2013-01-01

Stevens-Johnson syndrome and toxic epidermal necrolysis are acute mucocutaneous diseases primarily due to drug intake. The diseases are characterised by the separation of epidermis from dermis which can be life-threatening. Mortality is often caused by sepsis and multiple organ failure. The most...

Steven Moffat and Sue Vertue visits CERN

CERN Multimedia

Caraban Gonzalez, Noemi

2016-01-01

Steven William Moffat, OBE is a Scottish television writer and producer, known for his work as showrunner, writer and producer of the British television series Doctor Who and Sherlock. Susan "Sue" Nicola Vertue is an English television producer, mainly of comedy shows, including Mr. Bean and Coupling.

Stevens-Johnson syndrome in a patient with rheumatoid arthritis during long-term etanercept therapy.

Science.gov (United States)

Owczarczyk-Saczonek, Agnieszka; Zdanowska, Natalia; Znajewska-Pander, Aleksandra; Placek, Waldemar

2016-03-31

Etanercept and other anti-TNF-alpha agents have been indicated as a therapeutic option in severe drug reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis. Etanercept has been shown to quickly reduce the detachment of the epidermis and shorten healing time. Cases of etanercept-induced severe adverse drug reactions were also described. A 27-year-old woman with a 4-year history of etanercept and sulfasalazine treatment for rheumatoid arthritis was admitted with Stevens-Johnson syndrome. The patient received one dose of an OTC drug containing acetaminophen, phenylephrine and pheniramine two days prior to developing fist mucocutaneous symptoms. The most probable causative agent was paracetamol. Throughout the successful routine therapy of Stevens-Johnson syndrome etanercept therapy was continued. Sulfosalazin administration was stopped and administered again after recovery with no recurrence of the skin and mucosal symptoms. This case indicates that there is no justification for discontinuation of long-term anti-TNF-alpha treatment in patients who develop Stevens- Johnson syndrome / toxic epidermal necrolysis.

Born To Draw: A Profile of Steven Kellogg.

Science.gov (United States)

Elleman, Barbara

2001-01-01

Presents a profile of Steven Kellogg, an illustrator of children's books. Gives an overview of his career discussing how he got started and broke into the scene. Describes some of the books he has illustrated and relates his experiences with those books. (SG)

Musical Metaphors in the Poetry of Wallace Stevens

Directory of Open Access Journals (Sweden)

Victor Kennedy

2016-06-01

Full Text Available Wallace Stevens’s “The Man with the Blue Guitar” (1937 is widely recognized as one of the most important and influential poems of the 20th century. Inspired by Picasso’s painting The Old Guitarist, the poem in turn inspired Michael Tippett’s sonata for solo guitar, “The Blue Guitar” (Tippett 1983 and David Hockney’s The Blue Guitar: Etchings by David Hockney who was inspired by Wallace Stevens who was inspired by Pablo Picasso (Hockney and Stevens 1977. Central to “The Man with the Blue Guitar,” the metaphor of the musical instrument as a transformational symbol of the imagination is common in Stevens’s poems. The structure of “The Man with the Blue Guitar,” according to J. Hillis Miller, is the structure of stream-of-consciousness. Stevens’s poem creates what has been called “the deconstructed moment in modern poetry,” “an attempt to project a spatialized time that can be viewed from the privileged position of a timeless, static moment capable of encompassing a life at a glance” (Jackson 1982. This consciousness, which Derrida refers to as the “trace,” Stevens calls “the evasive movement of language.” The trace is the perception of the absence of meaning after the word or perception has passed, the glimpse of a hidden meaning that immediately vanishes. Stevens’s poem influenced not only other poets, artists and composers; references to and echoes of his ideas and techniques can be seen in popular music and culture well into the 21st century.

75 FR 24549 - Merchant Marine Act and Magnuson-Stevens Fishery Conservation and Management Act (Magnuson...

Science.gov (United States)

2010-05-05

... Management Act (Magnuson-Stevens Act) Provisions; Fishing Vessel, Fishing Facility and Individual Fishing... Fisheries Finance Program (FFP or the Program) provides long-term financing to the commercial fishing and...) lending program, 16 U.S.C. 1855(i)(1). The Magnuson-Stevens Fishery Conservation and Management...

Síndrome de Stevens-Johnson: Presentación de 1 caso

Directory of Open Access Journals (Sweden)

Luisa María Pacheco Álvarez

2001-12-01

Full Text Available El síndrome de Stevens-Johnson, es una enfermedad inflamatoria aguda, originada por una hipersensibilidad, que incluye la piel y las membranas mucosas; en una forma mayor pone en peligro la vida del paciente. Puede ser inducida por muchos factores precipitantes, desde los medicamentos hasta una infección. La afección se caracteriza por una súbita erupción morfológicamente variable, acompañada de estomatitis y oftalmia. En este trabajo se presenta un niño de 8 años de edad, con la entidad clínica en forma muy severa, el síndrome de Stevens-Johnson, que involucra manifestaciones cutáneas, oculares y de la mucosa oral, acompañada de otras complicaciones graves, por lo que requirió terapéutica en cuidados intensivos, y se logró una evolución satisfactoria del paciente.Stevens-Johnson syndrome is an acute inflammatory disease caused by a hypersensibility that includes the skin and the mucous membranes and that in a severe form endangers the patient’s life. It may be induced by many precipitating factors, from drugs to infection. The affection is characterized by a sudden morphologically variable rash, accompanied with stomatitis and ophthalmia. An 8-year-old boy suffering from this clinical entity in a very severe form, Stevens-Johnson syndrome, with skin , ocular and oral mucosa manifestations and with other serious complications, is presented in this paper. He had to be treated at the ICU and a satisfactory evolution was attained.

Fatal nevirapine-induced Stevens- Johnson syndrome with HIV ...

African Journals Online (AJOL)

2014-06-01

Jun 1, 2014 ... of Stevens-Johnson syndrome highlights the dilemmas and complications that may arise when prescribing multiple medications in HIV-associated ... HIV enters the central nervous system early in the course of HIV ... Affected individuals with SJS/TEN are genetically predisposed to developing severe ...

Genetics Home Reference: Stevens-Johnson syndrome/toxic epidermal necrolysis

Science.gov (United States)

... Hung SI. Recent advances in the genetics and immunology of Stevens-Johnson syndrome and toxic epidermal necrosis. ... 2012 May 29. Citation on PubMed or Free article on PubMed Central More from Genetics Home Reference ...

Risk of nevirapine-associated Stevens-Johnson syndrome among ...

African Journals Online (AJOL)

Background. Stevens-Johnson syndrome (SJS) is an acute life-threatening condition often elicited by drugs. The government's indecisiveness in deciding to stop the use of nevirapine (NVP) in HIV-infected pregnant women owing to the increase of SJS among this population group in South Africa prompted this investigation ...

Gamification is broken. An interview with Steven Poole

Directory of Open Access Journals (Sweden)

Marco Benoit Carbone

2012-05-01

Full Text Available Steven Poole is the author of Trigger Happy (2000. New York, NY: Arcade Publish, Unspeak (2006. New York, NY: Grove Press, and You Aren’t What You Eat (2012. In press. He has written extensively on books, culture, and videogames for The Guardian and other publications.

77 FR 69929 - Western Carolina Railway Service Corporation, Steven C. Hawkins and Cheryl R. Hawkins-Continuance...

Science.gov (United States)

2012-11-21

... Railway Service Corporation, Steven C. Hawkins and Cheryl R. Hawkins--Continuance in Control Exemption--Aiken Railway Company, LLC Western Carolina Railway Service Corporation (WCRS) and Steven C. Hawkins and Cheryl R. Hawkins (the Hawkins) (collectively, Applicants) have filed a verified notice of exemption...

Evaluation of conjunctival bacterial flora in patients with Stevens-Johnson Syndrome

Directory of Open Access Journals (Sweden)

Luciana Frizon

2014-03-01

Full Text Available OBJECTIVE: To determine the conjunctival bacterial flora present in patients with Stevens-Johnson syndrome. METHODS: A prospective study of the conjunctival bacterial flora was performed in 41 eyes of 22 patients with Stevens-Johnson syndrome. The information gathered included the patient's sex and age, the duration of disease, the cause of Stevens-Johnson syndrome, and treatments. Scrapings of the inferior conjunctival fornix were performed in both eyes. Fourteen days before scraping, the patients were asked to interrupt all topical medication and start using 0.5% nonpreserved methylcellulose. The microbiological evaluation included microorganism identification and determination of antibiotic sensitivity. RESULTS: Of 22 patients (41 eyes, 14 (64% were females, and eight (36% were males. The mean age was 33.2 years, and the mean duration of disease was 15.6 years. Visual acuity ranged from light perception to 20/25 (1.57 logMar. The treatment received by most patients consisted of tear substitutes, topical antibiotics, and contact lenses. Bacterial identification was positive in 39 eyes (95% and negative in two eyes (5%. Gram-positive cocci accounted for 55.5% of the microorganisms, whereas gram-positive bacilli and gram-negative bacilli accounted for 19% and 25.5%, respectively. Half of the patients (54% had multiple bacterial species in their flora, and only one bacterial species was identified in the other half. Resistant bacteria were isolated from four eyes. The antibiotic sensitivity results for the Streptococcus group showed the lowest sensitivity and the highest microbial resistance identified. CONCLUSION: Patients with Stevens-Johnson syndrome have a diverse conjunctival flora that includes many pathogenic species.

Award for Distinguished Scientific Contributions: Steven F. Maier

Science.gov (United States)

American Psychologist, 2009

2009-01-01

Steven F. Maier, winner of the Award for Distinguished Scientific Contributions, is cited for his work in the fields of learned helplessness; cytokines, depressed mood, and cognitive interference; and the brain structures that produce and counteract learned helplessness. In addition to the citation, a biography and selected bibliography of Maier's…

Bronchiolitis obliterans in children with Stevens-Johnson syndrome: follow-up with high resolution CT

International Nuclear Information System (INIS)

Kim, M.J.; Lee, K.Y.

1996-01-01

About one third of children with Stevens-Johnson syndrome have pulmonary involvement. As a consequence of airway epithelial injury, bronchiolitis obliterans can occur in these patients. Two cases of Stevens-Johnson syndrome-associated bronchiolitis obliterans in children were diagnosed and followed by high resolution CT without open lung biopsy. Serial changes of high resolution CT features of bronchiolitis obliterans are discussed and the literature is reviewed. (orig.)

Holokaust Steven Spielbergi pilgu läbi / Andres Laasik

Index Scriptorium Estoniae

Laasik, Andres, 1960-2016

2000-01-01

Oscari võitnud dokumentaalfilm "Need viimased päevad" ("The Last Days") : režissöör James Moll : Tootja Steven Spielbergi loodud Survivors of the Shoah Visual History Foundation : Ameerika Ühendriigid 1999. Filmi esitlusest Eesti Vabariigi Välisministeeriumis

Justice John Paul Stevens and the Erotic Boomerang.

Science.gov (United States)

Lieberman, Marc

Justice John Paul Stevens of the United States Supreme Court has ruled on obscenity cases in seven instances since his appointment. His rulings reveal that he regards obscenity as a nuisance rather than as a danger threatening to undermine the nation's morality, that he supports a nationwide standard to adjudicate obscenity cases, and that he…

77 FR 27436 - Stevens Institute of Technology, et al.; Notice of Consolidated Decision on Applications for Duty...

Science.gov (United States)

2012-05-10

... Number: 12-014. Applicant: California Institute of Technology, Pasadena, CA 91125. Instrument: Nova Nano... DEPARTMENT OF COMMERCE International Trade Administration Stevens Institute of Technology, et al... Constitution Avenue NW, Washington, DC Docket Number: 12-008. Applicant: Stevens Institute of Technology...

Concurrence of Stevens-Johnson Syndrome and Bilateral Parotitis after Minocycline Therapy

Directory of Open Access Journals (Sweden)

Jimi Yoon

2010-06-01

Full Text Available Minocycline is an antibiotic of tetracycline derivatives that is commonly used in the treatment of moderate to severe acne vulgaris. It has been reported to cause rare adverse events from mild cutaneous eruption to severe forms including drug-induced lupus, serum sickness-like reaction, and hypersensitivity reactions, etc. The risks of adverse events attributed to minocycline have not been ascertained reliably and there are concerns about the safety of minocycline which could possibly result in life-threatening events such as the Stevens-Johnson syndrome. Here we demonstrate an unusual case of Stevens-Johnson syndrome in conjunction with bilateral parotitis after the intake of minocycline in a Korean boy suggesting discreet use of the drug.

Steven Vogel was an eminent American biophysicist. He made ...

Indian Academy of Sciences (India)

2016-08-26

Aug 26, 2016 ... Steven Vogel was a pinoneer in applying principles of mechanics to diverse living systems. This article first provides a brief overview of his career. It then reviews the concepts of P´eclet number and Reynolds number which are helpful in appreciating the Classics article by Vogel reproduced in this issue.

A review of current practices and the future for deep well injection in the upper Miocene Stevens sand, Kern County, California

International Nuclear Information System (INIS)

Kiser, S.C.; Chenot, D.W.

1991-01-01

Waste-water disposal is a major concern of the petroleum business, especially because of complications associated with many produced-water surface-impoundment percolation facilities. In the San Joaquin Valley, California, the current environmental regulations protecting the potentially usable groundwaters are stringent. the Stevens has significant potential as a disposal zone that may offer considerable capacity when the project is designed using proper geologic and engineering studies. The Stevens sands are well known for their oil-producing capabilities, however, not much has been published regarding its suitability as a zone for deep well injection. Conditions that make the Stevens potentially suitable include (1) adequate confinement providing geologic separation from the groundwater sources in the basin, (2) storage capacity, and (3) large areal extent. Because the search for acceptable disposal options is becoming critical, the current class II disposal options is becoming critical, the current class II disposal activities in the Stevens sands were reviewed and the areas offering the greatest future potential were identified. The authors then discuss class II disposal projects in Stevens sands in the West Bellevue and Midway Sunset oil fields and estimate the ultimate basin-wide disposal capacity of the Stevens

Stevens-Johnson Syndrome After Armodafinil Use.

Science.gov (United States)

Holfinger, Steven; Roy, Asim; Schmidt, Markus

2018-05-15

We present the case of a 21-year-old woman in whom Stevens-Johnson syndrome (SJS) developed after initiation of armodafinil. Although this rare and life-threatening reaction is listed on armodafinil's label, no cases have been reported in the literature. This case, in addition to an update of the drug's label after post-marketing research, both support the link between armodafinil and SJS. Providers should maintain a high clinical suspicion for SJS when starting therapy to minimize associated morbidity and mortality by discontinuing armodafinil at the onset of first symptoms. © 2018 American Academy of Sleep Medicine.

Steven MacCall: Winner of LJ's 2010 Teaching Award

Science.gov (United States)

Berry, John N., III

2010-01-01

This article profiles Steven L. MacCall, winner of "Library Journal's" 2010 Teaching Award. An associate professor at the School of Library and Information Studies (SLIS) at the University of Alabama, Tuscaloosa, MacCall was nominated by Kathie Popadin, known as "Kpop" to the members of her cohort in the online MLIS program at SLIS. Sixteen of…

Synthesis of (±)-amathaspiramide F and discovery of an unusual stereocontrolling element for the [2,3]-Stevens rearrangement.

Science.gov (United States)

Soheili, Arash; Tambar, Uttam K

2013-10-04

A formal total synthesis of (±)-amathaspiramide F through a tandem palladium-catalyzed allylic amination/[2,3]-Stevens rearrangement is reported. The unexpected diastereoselectivity of the [2,3]-Stevens rearrangement was controlled by the substitution patterns of an aromatic ring. This discovery represents a new stereocontrolling element for [2,3]-sigmatropic rearrangements in complex molecular settings.

Comparison of Olive Tipped and Conventional Steven's Cannula for Sub-Tenon Ophthalmic Anesthesia.

Science.gov (United States)

Al-Motowa, Saeed; Ahmad, Nauman; Khandekar, Rajiv; Zahoor, Abdul

2016-01-01

To compare the efficacy of the olive tipped (OT) cannula to the conventional Steven's cannula for sub-Tenon block (STB) before cataract surgery. This prospective, randomized, double-masked compared STB delivered in cataract surgery patients with an OT cannula or a conventional Steven's cannula (ST). Outcome variables included the akinesia score and lid movement scores at 5 and 10 min. The patient perception of pain during delivery of the STB and surgery were also compared between groups. Surgeon satisfaction with anesthesia was compared between groups. P <0.05 was statistically significant. There were sixty patients in each group. The age between groups was not statistically different ( P = 0.4). The body mass index was higher in the ST group compared to the OT group ( P < 0.001). The akinesia score at 5 and 10 min did not differ between groups ( P = 0.07 and P = 0.6, respectively). The patient perception of pain during STB and surgery were similar between groups ( P = 0.1 and P = 0.06, respectively). There were six patients with mild chemosis and redness in the OT group and 15 patients in the ST group. An OT cannula is equally effective as the conventional Steven's cannula for delivering STB anesthesia before cataract surgery.

Are steroids effective in toxic epidermal necrolysis and Stevens-Johnson syndrome?

Directory of Open Access Journals (Sweden)

Rodrigo Meza

2017-06-01

Full Text Available Resumen La necrólisis epidérmica tóxica y el síndrome de Stevens-Johnson son reacciones cutáneas adversas graves a medicamentos e infecciones. Los corticoides se describen como una alternativa terapéutica, sin embargo, su uso es aún controvertido. Utilizando la base de datos Epistemonikos, la cual es mantenida mediante búsquedas en múltiples bases de datos, identificamos cuatro revisiones sistemáticas que en conjunto incluyen once estudios primarios que responden la pregunta de interés. Extrajimos los datos y preparamos una tabla de resumen de los resultados utilizando el método GRADE. Concluimos que no está claro si los corticoides disminuyen la mortalidad o la estadía hospitalaria en la necrólisis epidérmica tóxica y el síndrome de Stevens-Johnson porque la certeza de la evidencia es muy baja.

Stevens-Johnson syndrome associated with Malarone antimalarial prophylaxis.

Science.gov (United States)

Emberger, Michael; Lechner, Arno Michael; Zelger, Bernhard

2003-07-01

To the best of our knowledge, Stevens-Johnson syndrome (SJS) has not been reported previously as an adverse reaction to Malarone, which is a combination of atovaquone and proguanil hydrochloride used for antimalarial prophylaxis and therapy. We describe a 65-year-old patient who had SJS with typical clinical and histopathological findings associated with the use of Malarone prophylaxis for malaria. This report should alert physicians to this severe cutaneous reaction, and Malarone should be added to the list of drugs that can potentially cause SJS.

2012 ARPA-E Energy Innovation Summit: Fireside Chat with Steven Chu and Bill Gates

Energy Technology Data Exchange (ETDEWEB)

Chu, Steven; Gates, Bill; Podesta, John

2012-02-28

The third annual ARPA-E Energy Innovation Summit was held in Washington D.C. in February, 2012. The event brought together key players from across the energy ecosystem - researchers, entrepreneurs, investors, corporate executives, and government officials - to share ideas for developing and deploying the next generation of energy technologies. This video captures a session called Fireside Chat that featured Steven Chu, the Secretary of Energy, and Bill Gates, Chairman of Microsoft Corporation. The session is moderated by John Podesta, Chair of the Center for American Progress. Energy Secretary Steven Chu and Microsoft Founder and Chairman Bill Gates exchanged ideas about how small businesses and innovators can overcome the challenges that face many startups.

Pediatric Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Halted by Etanercept.

Science.gov (United States)

Gavigan, Geneviève M; Kanigsberg, Nordau D; Ramien, Michele L

2018-02-01

We report a case of an 11-year-old female with Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) overlap, most likely triggered by sulfamethoxazole-trimethoprim, who was treated with the combination of methylprednisolone, cyclosporine, and etanercept. Her condition stabilized and her skin involvement did not progress after the addition of etanercept. To our knowledge, this is the first report of etanercept for pediatric SJS/TEN.

Steven Spielberg: My Primary Purpose in Making "Schindler's List" Was for Education.

Science.gov (United States)

Feinberg, Stephen; Totten, Samuel

1995-01-01

Presents an interview with Steven Spielberg on his goals and methods for making "Schindler's List." Maintains that the important lessons of truth and tolerance will help prevent the Holocaust from happening again. Describes cooperative ventures with educational groups to develop instructional materials associated with the film. (CFR)

Steven Spielberg's "Amistad": Film as History and the Trivializing of History Teaching.

Science.gov (United States)

Butchart, Ronald E.

1999-01-01

Asserts that Steven Spielberg's film "Amistad" fictionalizes the overall facts of the case by inaccurately portraying many of the events that occurred. Explains that the myth-making tradition of Hollywood changes the messages derived from the Amistad court case. Critiques the teaching kit that corresponds to the movie. (CMK)

Review of The Joy of x: A Guided Tour of Math, from One to Infinity by Steven Strogatz

OpenAIRE

Michael T. Catalano

2014-01-01

Strogatz, Steven. The Joy of x: A Guided Tour of Math, from One to Infinity, (New York, NY, Houghton Mifflin Harcourt, 2012). 316 pp. ISBN 978-0-547-51765-0 The Joy of x: A Guided Tour of Math, from One to Infinity, by Steven Strogatz, is an engaging and example-filled argument for mathematics as a valuable and enjoyable activity. The thirty chapters are divided into six parts, entitled Numbers, Relationships, Shapes, Change, Data, and Frontiers. The discussion ranges from intuitive expl...

Steven Spielberg peab oma uut filmi koostööks Stanley Kubrickuga

Index Scriptorium Estoniae

2001-01-01

30. juunil üheaegselt Jaapanis ja USAs esilinastub Steven Spielbergi "Tehisintellekt" ("A.I. Artificial Intelligence"), mille kohta režissöör Tokyos pressikonverentsil väitis, et see on õieti Stanley Kubricku film, kuna põhineb temast järelejäänud 90-leheküljelisel ideeprojektil

Characterization of fish sauce aroma-impact compounds using GC-MS, SPME-Osme-GCO, and Stevens' power law exponents.

Science.gov (United States)

Pham, A J; Schilling, M W; Yoon, Y; Kamadia, V V; Marshall, D L

2008-05-01

The objectives of this study were to characterize volatile compounds and to determine the characteristic aromas associated with impact compounds in 4 fish sauces using solid-phase micro-extraction, gas chromatography-mass spectrometry, Osme, and gas chromatography olfactometry (SPME-Osme-GCO) coupled with Stevens' Power Law. Compounds were separated using GCMS and GCO and were identified with the mass spectral database, aroma perceived at the sniffing port, retention indices, and verification of compounds by authentic standards in the GCMS and GCO. Aromas that were isolated and present in all 4 fish sauce samples at all concentrations included fishy (trimethylamine), pungent and dirty socks (combination of butanoic, pentanoic, hexanoic, and heptanoic acids), cooked rice and buttery popcorn (2,6-dimethyl pyrazine), and sweet and cotton candy (benzaldehyde). All fish sauces contained the same aromas as determined by GCO and GCMS (verified using authentic standard compounds), but the odor intensity associated with each compound or group of compounds was variable for different fish sauce samples. Stevens' Power Law exponents were also determined using this analytical technique, but exponents were not consistent for the same compounds that were found in all fish sauces. Stevens' Power Law exponents ranged from 0.14 to 0.37, 0.24 to 0.34, 0.09 to 0.21, and 0.10 to 0.35 for dirty socks, fishy, buttery popcorn, and sweet aromas, respectively. This demonstrates that there is variability in Stevens' Power Law exponents for odorants within fish sauce samples.

Alfred Russel Wallace’s record of his consignments to Samuel Stevens, 1854-1861

NARCIS (Netherlands)

Baker, D.B.

2001-01-01

An annotated facsimile of those pages of Alfred Russel Wallace’s notebook recording his consignments from the Malay Archipelago to his London agent, Samuel Stevens, is provided. Records of individual consignments are linked with the stages of Wallace’s and Charles Allen’s itineraries to which they

LX-04 VIOLENCE MEASUREMENTS- STEVEN TESTS IMPACTED BY PROJECTILES SHOT FROM A HOWITZER GUN

International Nuclear Information System (INIS)

Chidester, S K; Vandersall, K S; Switzer, L L; Tarver, C M

2005-01-01

Characterization of the reaction violence of LX-04 explosive (85% HMX and 15% Viton A by weight) was obtained from Steven Impact Tests performed above the reaction initiation threshold. A 155 mm Howitzer propellant driven gas gun was used to accelerate the Steven Test projectiles in the range of approximately 170-300 m/s to react (ignite) the LX-04 explosive. Blast overpressure gauges, acoustic microphones, and high-speed photography characterized the level of high explosive reaction violence. A detonation in this velocity range was not observed and when comparing these results (and the Susan test results) with that of other HMX based explosives, LX-04 has a more gradual reaction violence slope as the impact velocity increases. The high binder content (15%) of the LX-04 explosive is believed to be the key factor to the lower level of violence

Some assembly required: Contributions of Tom Stevens' lab to the V-ATPase field.

Science.gov (United States)

Graham, Laurie A; Finnigan, Gregory C; Kane, Patricia M

2018-06-01

Tom Stevens' lab has explored the subunit composition and assembly of the yeast V-ATPase for more than 30 years. Early studies helped establish yeast as the predominant model system for study of V-ATPase proton pumps and led to the discovery of protein splicing of the V-ATPase catalytic subunit. The Vma - phenotype, characteristic of loss-of-V-ATPase activity in yeast was key in determining the enzyme's subunit composition via yeast genetics. V-ATPase subunit composition proved to be highly conserved among eukaryotes. Genetic screens for new vma mutants led to identification of a set of dedicated V-ATPase assembly factors and helped unravel the complex pathways for V-ATPase assembly. In later years, exploration of the evolutionary history of several V-ATPase subunits provided new information about the enzyme's structure and function. This review highlights V-ATPase work in the Stevens' lab between 1987 and 2017. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

78 FR 21114 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

Science.gov (United States)

2013-04-09

... for Sustainable Fisheries, Northeast Region, NMFS (Assistant Regional Administrator), has made a... University Cooperative Extension of Suffolk County, NY. Regulations under the Magnuson-Stevens Fishery... limits to conduct onboard sampling. This project proposes to evaluate bottom trawl modifications as a...

78 FR 32375 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

Science.gov (United States)

2013-05-30

..., Dartmouth, School for Marine Science and Technology. Regulations under the Magnuson-Stevens Fishery.... SUPPLEMENTARY INFORMATION: The University of Massachusetts, Dartmouth, School for Marine Science and Technology... study and examining the influence of temperature. To facilitate compensation fishing in support of this...

78 FR 38693 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

Science.gov (United States)

2013-06-27

... Massachusetts, Dartmouth, School for Marine Science and Technology. Regulations under the Magnuson-Stevens..., 978-281-9177. SUPPLEMENTARY INFORMATION: The University of Massachusetts, Dartmouth, School for Marine... preliminary determination that an exempted fishing permit application contains all of the required information...

78 FR 21913 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

Science.gov (United States)

2013-04-12

... Massachusetts, Dartmouth, School for Marine Science and Technology. Regulations under the Magnuson-Stevens... preliminary determination that an exempted fishing permit application contains all of the required information....'' Fax: (978) 281-9135. FOR FURTHER INFORMATION CONTACT: Jason Berthiaume, Fishery Management Specialist...

Stevens-Johnson syndrome following use of metronidazole in a dental patient.

Science.gov (United States)

Mazumdar, Goutameswar; Shome, Koushik

2014-01-01

Metronidazole alone rarely causes Stevens-Johnson syndrome (SJS). We present a case of an elderly male patient who, following metronidazole use, developed neurological symptoms followed by pain and blisters on both soles, erythema of face and neck, scrotal itching and erosion, and hemorrhagic encrustation around the lips and oral mucous membrane. Initial neurological symptoms followed by mucocutaneous manifestation of SJS following metronidazole use is probably a new presentation of this case.

Guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis: An Indian perspective.

Science.gov (United States)

Gupta, Lalit Kumar; Martin, Abhay Mani; Agarwal, Nidheesh; D'Souza, Paschal; Das, Sudip; Kumar, Rajesh; Pande, Sushil; Das, Nilay Kanti; Kumaresan, Muthuvel; Kumar, Piyush; Garg, Anubhav; Singh, Saurabh

2016-01-01

Stevens-Johnson syndrome and toxic epidermal necrolysis are severe, life-threatening mucocutaneous adverse drug reactions with a high morbidity and mortality that require immediate medical care. The various immunomodulatory treatments include systemic corticosteroids, cyclosporine, intravenous immunoglobulin, cyclophosphamide, plasmapheresis and tumor necrosis factor-α inhibitors. The ideal therapy of Stevens-Johnson syndrome/toxic epidermal necrolysis still remains a matter of debate as there are only a limited number of studies of good quality comparing the usefulness of different specific treatments. The aim of this article is to comprehensively review the published medical literature and frame management guidelines suitable in the Indian perspective. The Indian Association of Dermatologists, Venereologists and Leprologists (IADVL) assigned the task of preparing these guidelines to its special interest group on cutaneous adverse drug reactions. The group performed a comprehensive English language literature search for management options in Stevens-Johnson syndrome/toxic epidermal necrolysis across multiple databases (PubMed, EMBASE, MEDLINE and Cochrane) for keywords (alone and in combination) and MeSH items such as "guidelines," "Stevens-Johnson syndrome," "toxic epidermal necrolysis," "corticosteroids," "intravenous immunoglobulin," "cyclosporine" and "management." The available evidence was evaluated using the strength of recommendation taxonomy and graded using a three-point scale. A draft of clinical recommendations was developed on the best available evidence which was also scrutinized and critically evaluated by the IADVL Academy of Dermatology. Based on the inputs received, this final consensus statement was prepared. A total of 104 articles (meta-analyses, prospective and retrospective studies, reviews [including chapters in books], previous guidelines [including Indian guidelines of 2006] and case series) were critically evaluated and the evidence

76 FR 11857 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

Science.gov (United States)

2011-03-03

.... The pollock peer-reviewed benchmark stock assessment review (Stock Assessment Workshop, or SAW, 50... overfishing, rebuild overfished stocks, achieve optimum yield (OY), and minimize the economic impact of... Management Act (Magnuson-Stevens Act). This action would revise the biological reference points and stock...

Investigation of Monnose-Binding Lectin gene Polymorphism in Patients with Erythema Multiforme, Stevens-Johnson Syndrome and Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Overlap Syndrome

Directory of Open Access Journals (Sweden)

Sevil Toka

2012-09-01

Full Text Available Objective: Monnose-Binding lectin (MBL appears to play an important role in the immune system. The genetic polymorphisms in the MBL2 gene can result in a reduction of serum levels, leading to a predisposition to recurrent infection. The aim of this study is to investigate the influence of a polymorphism in codon 54 of the MBL2 gene on the susceptibility to Erythema Multiforme, Stevens-Johnson Syndrome and Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Overlap Syndrome (EM, SJS and SJS/TEN overlap syndrome. Material and Methods: Our study included 64 patients who were clinically and/or histopathologically diagnosed with EM, SJS, and SJS/TEN overlap syndrome and 66 healthy control subjects who were genotyped for the MBL2 gene codon 54 polymorphism using the PCR-RFLP method. For all statistical analyses, the level of significance was set at p<0.05. Results: The prevalence of the B allele was 18% in the EM, SJS and SJS/TEN patient groups and 13% in the control group. No significant differences in allele frequencies of any polymorphism were observed between the patient and control groups, although the B allele was more frequent in the patient groups (p=0.328.Conclusion: Our results provide no evidence of a relationship between MBL2 gene codon 54 polymorphism and the susceptibility to EM, SJS and SJS/TEN overlap syndrome. However, these findings should be confirmed in studies with a larger sample size.

Endoscopic cyclophotocoagulation in refractory glaucoma after osteo-odonto-keratoprosthesis in Stevens-Johnson syndrome: a case report.

Science.gov (United States)

Forlini, Matteo; Adabache-Guel, Tania; Bratu, Adriana; Rossini, Paolo; Mingaine, Mpekethu Sam; Cavallini, Gian Maria; Forlini, Cesare

2014-01-01

To report successful treatment of refractive glaucoma in a patient submitted to osteo-odonto-keratoprosthesis surgery for Stevens-Johnson syndrome. An interventional case report. The patient is a 62-year-old Indian man with known Stevens-Johnson syndrome since 1972 secondary to tetracycline therapy, with bilateral dry eye and corneal blindness. He underwent symblepharon release surgery with mucous membrane graft in both eyes. Osteo-odonto-keratoprosthesis surgery was later performed on the left eye. He was submitted to 2 Ahmed valve implants to control secondary glaucoma but visual fields continued to worsen; hence, he underwent endoscopic 140° cyclophotocoagulation with a good control of IOP. Endoscopic cyclophotocoagulation as alternative treatment provides good results in refractory glaucoma after osteo-odonto-keratoprosthesis surgery.

77 FR 16942 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

Science.gov (United States)

2012-03-23

... Multispecies Fishery Management Plan which was approved on March 8, 2012. This action amends the Northeast Multispecies Fishery Management Plan to explicitly define and facilitate the effective operation of state.... 110901552-20494-02] RIN 0648-BB34 Magnuson-Stevens Fishery Conservation and Management Act Provisions...

76 FR 56985 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

Science.gov (United States)

2011-09-15

... to estimate total haddock catch by the herring midwater trawl fleet in these herring management areas.... 110627355-1539-02] RIN 0648-BB08 Magnuson-Stevens Fishery Conservation and Management Act Provisions... the NE Multispecies Fishery Management Plan (FMP), which increases the haddock incidental catch cap...

Stevens Johnson Syndrome in a patient undergoing gynaecological brachytherapy: An association or an incident?

International Nuclear Information System (INIS)

Ferreira, M. R.; Amado, A.; Jorge, M.; Grillo, I. M.

2011-01-01

Background: Stevens Johnson Syndrome and Erythema Multiforme are hypersensitivity skin reactions generally arising in the context of multiple causes. Radiation therapy is considered to be one of these causes, although most reports are hindered by concomitant medications. Aim: The aim of this paper was to present a case of Stevens Johnson Syndrome arising in a patient undergoing gynaecological brachytherapy with an unusual presentation. Case:We describe a case of a 56-year-old woman with endometrial cancer undergoing adjuvant gynaecological radiotherapy. While undergoing a gynaecological brachytherapy boost, she developed bilateral conjunctivitis that progressed to oral mucositis and pruritic erythema with sloughing of the skin on her arms and legs but not the torso or irradiated fields (namely the vaginal mucosa). Conclusion: This case illustrates the association of RT/SJS; however, it also raises the question of patients undergoing RT being more susceptible to SJS as opposed to a direct cause of the disease. (authors)

78 FR 63892 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

Science.gov (United States)

2013-10-25

.../13monkeia.html . Copies of the small entity compliance guide are available at the following internet address... Procedure Act (APA). Pursuant to section 305(c)(3)(B) of the Magnuson-Stevens Act, management measures... APA. Comments and Responses Fifteen comments were received during the public comment period on the...

Eliminating cancer stem cells: an interview with CCR’s Steven Hou | Center for Cancer Research

Science.gov (United States)

Steven Hou, Ph.D., senior investigator in the Basic Research Laboratory at the Center for Cancer Research describes his latest research that has uncovered potential ways to eliminate cancer stem cells and may offer hope to patients with reoccurring tumors.  Learn more...

Autoimmune Progesterone Dermatitis Presenting as Stevens-Johnson Syndrome.

Science.gov (United States)

Drayer, Sara M; Laufer, Larry R; Farrell, Maureen E

2017-10-01

Autoimmune progesterone dermatitis is an uncommon disease presenting with cyclical skin eruptions corresponding with the menstrual cycle luteal phase. Because symptoms are precipitated by rising progesterone levels, treatment relies on hormone suppression. A 22-year-old nulligravid woman presented with symptoms mistaken for Stevens-Johnson syndrome. A cyclic recurrence of her symptoms was noted, and the diagnosis of autoimmune progesterone dermatitis was made by an intradermal progesterone challenge. After 48 months, she remained refractory to medical management and definitive surgical treatment with bilateral oophorectomy was performed. Autoimmune progesterone dermatitis is a challenging diagnosis owing to its rarity and variety of clinical presentations. Treatment centers on suppression of endogenous progesterone and avoidance of exogenous triggers. When these modalities fail, surgical management must be undertaken.

Stevens-Johnson syndrome progressing to toxic epidermal necrolysis with haloperidol and carbamazepine combination

Directory of Open Access Journals (Sweden)

Ajay Kumar

2011-01-01

Full Text Available Carbamazepine and other anticonvulsants are commoner cause of severe adverse cutaneous drug reactions such as erythema multiforme, toxic epidermal necrolysis (TEN, and Stevens-Johnson syndrome (SJS. We report a case of SJS rapidly progressing to TEN with a combination of haloperidol and carbamazepine in a patient with bipolar affective disorder. The pathophysiological mechanism underlying this reaction is discussed.

What Recourse for the Principal Abused by Community Activists? The Case of "Stevens v. Tillman."

Science.gov (United States)

Menacker, Julius

1990-01-01

"Stevens v. Tillman" illustrates the limited reach of federal law in controversies where community activists use extreme, even illegal, methods to exert their will over objecting school officials. Defamation charges against activists for verbal abuses will apparently be very difficult to sustain, given court views that being called a…

76 FR 43745 - Magnuson-Stevens Fishery Conservation and Management Act (MSA) Provisions; Fisheries of the...

Science.gov (United States)

2011-07-21

... during the course of the FY. Management uncertainty for the LAGC IFQ fleet is considered very low because... incorporate ACT into the LAGC IFQ fleet allocation, but chose not to apply any management uncertainty buffer... Atmospheric Administration 50 CFR Part 648 Magnuson-Stevens Fishery Conservation and Management Act (MSA...

78 FR 25685 - Magnuson-Stevens Act Provisions; Implementation of the Shark Conservation Act of 2010

Science.gov (United States)

2013-05-02

.... 111014628-3329-01] RIN 0648-BB54 Magnuson-Stevens Act Provisions; Implementation of the Shark Conservation... implement the provisions of the Shark Conservation Act of 2010 (SCA) and prohibit any person from removing any of the fins of a shark at sea, possessing shark fins on board a fishing vessel unless they are...

Detection of an ylide intermediate in the electrochemically-induced Stevens rearrangement of an ammonium salt by in situ UV–vis spectroelectrochemistry

International Nuclear Information System (INIS)

Capobianco, Amedeo; Caruso, Tonino; Palombi, Laura; Peluso, Andrea

2013-01-01

Highlights: ► Mechanistic insights of the electro-induced Stevens rearrangement are provided. ► The reduction of PhCOCH 2 N + (CH 3 ) 2 CH 2 Ph is ascribed to a one-electron transfer process. ► An electrogenerated ammonium ylide has been detected by UV-spectroelectrochemistry. -- Abstract: The electrochemically-induced Stevens rearrangement of 2-(benzyldimethyl)ammonium acetophenone has been investigated by in situ UV–vis spectroelectrochemistry. Voltammetric analysis and absorption spectra recorded during the potentiostatic reduction indicate that the reaction proceeds via a one-electron transfer with a Platinum cathode and generation of an ammonium ylide intermediate

Low amplitude impact of PBX 9501: Modified Steven spigot gun tests

Energy Technology Data Exchange (ETDEWEB)

Idar, D.J.; Lucht, R.A.; Straight, J.W. [and others

1998-12-01

Low-velocity mechanical impact and subsequent high explosive (HE) reaction are of concern in credible accident scenarios involving the handling, transport, and storage of nuclear weapons. Using modified Steven spigot gun tests, the authors have investigated the high-explosive violent-reaction (HEVR) potential of PBX 9501 to low-amplitude insult. Reliable modeling predictions require that one identify the relevant parameters and behavioral responses that are key to the reaction mechanism(s) in PBX 9501. Additional efforts have been targeted at identifying relevant differences in the response between baseline and stockpile-aged PBX 9501 to low-velocity impacts.

Síndrome de Stevens-Johnson: presentación de un caso

OpenAIRE

Fernández Brizuela, Ener de Jesús; Morales Díaz, Felicia

2011-01-01

Fundamento: el síndrome de Stevens-Johnson, también llamado eritema multiforme mayor, se caracteriza por una serie de lesiones cutáneas de diversa morfología, es una grave lesión en la cual están afectadas al menos dos membranas mucosas y la piel. La patogenia de esta enfermedad es desconocida aunque generalmente se considera que es provocada por una reacción de hipersensibilidad a drogas, infecciones y exposición a sustancias tóxicas. Caso clínico: esta afección fue diagnosticada en un niño ...

78 FR 36149 - Magnuson-Stevens Act Provisions; Implementation of the Shark Conservation Act of 2010; Correction

Science.gov (United States)

2013-06-17

.... 111014628-3329-01] RIN 0648-BB54 Magnuson-Stevens Act Provisions; Implementation of the Shark Conservation.... SUMMARY: NMFS published a proposed rule on May 2, 2013, to implement provisions of the Shark Conservation Act of 2010 (SCA) that prohibit any person from removing any of the fins of a shark at sea, possessing...

78 FR 40687 - Magnuson-Stevens Act Provisions; Implementation of the Shark Conservation Act of 2010; Extension...

Science.gov (United States)

2013-07-08

.... 111014628-3329-01] RIN 0648-BB54 Magnuson-Stevens Act Provisions; Implementation of the Shark Conservation... period. SUMMARY: NMFS published a proposed rule on May 2, 2013, to implement provisions of the Shark Conservation Act of 2010 (SCA) that prohibit any person from removing any of the fins of a shark at sea...

Tandem catalytic allylic amination and [2,3]-Stevens rearrangement of tertiary amines.

Science.gov (United States)

Soheili, Arash; Tambar, Uttam K

2011-08-24

We have developed a catalytic allylic amination involving tertiary aminoesters and allylcarbonates, which is the first example of the use of tertiary amines as intermolecular nucleophiles in metal-catalyzed allylic substitution chemistry. This process is employed in a tandem ammonium ylide generation/[2,3]-rearrangement reaction, which formally represents a palladium-catalyzed Stevens rearrangement. Low catalyst loadings and mild reaction conditions are compatible with an unprecedented substrate scope for the ammonium ylide functionality, and products are generated in high yields and diastereoselectivities. Mechanistic studies suggested the reversible formation of an ammonium intermediate.

Fundamental Flaws In The Derivation Of Stevens' Law For Taste Within Norwich's Entropy Theory of Perception

International Nuclear Information System (INIS)

Nizami, Lance

2010-01-01

Norwich's Entropy Theory of Perception (1975-present) is a general theory of perception, based on Shannon's Information Theory. Among many bold claims, the Entropy Theory presents a truly astounding result: that Stevens' Law with an Index of 1, an empirical power relation of direct proportionality between perceived taste intensity and stimulus concentration, arises from theory alone. Norwich's theorizing starts with several extraordinary hypotheses. First, 'multiple, parallel receptor-neuron units' without collaterals 'carry essentially the same message to the brain', i.e. the rate-level curves are identical. Second, sensation is proportional to firing rate. Third, firing rate is proportional to the taste receptor's 'resolvable uncertainty'. Fourth, the 'resolvable uncertainty' is obtained from Shannon's Information Theory. Finally, 'resolvable uncertainty' also depends upon the microscopic thermodynamic density fluctuation of the tasted solute. Norwich proves that density fluctuation is density variance, which is proportional to solute concentration, all based on the theory of fluctuations in fluid composition from Tolman's classic physics text, 'The Principles of Statistical Mechanics'. Altogether, according to Norwich, perceived taste intensity is theoretically proportional to solute concentration. Such a universal rule for taste, one that is independent of solute identity, personal physiological differences, and psychophysical task, is truly remarkable and is well-deserving of scrutiny. Norwich's crucial step was the derivation of density variance. That step was meticulously reconstructed here. It transpires that the appropriate fluctuation is Tolman's mean-square fractional density fluctuation, not density variance as used by Norwich. Tolman's algebra yields a 'Stevens Index' of -1 rather than 1. As 'Stevens Index' empirically always exceeds zero, the Index of -1 suggests that it is risky to infer psychophysical laws of sensory response from information theory

Stevens-Johnson syndrome and toxic epidermal necrolysis: an update on pharmacogenetics studies in drug-induced severe skin reaction.

Science.gov (United States)

Rufini, Sara; Ciccacci, Cinzia; Politi, Cristina; Giardina, Emiliano; Novelli, Giuseppe; Borgiani, Paola

2015-11-01

Stevens-Johnson syndrome and toxic epidermal necrolysis are severe, life-threatening drug reactions involving skin and membranes mucous, which are associated with significant morbidity and mortality and triggered, especially by drug exposure. Different studies have demonstrated that drug response is a multifactorial character and that the interindividual variability in this response depends on both environmental and genetic factors. The last ones have a relevant significance. In fact, the identification of new specific genetic markers involved in the response to drugs, will be of great utility to establish a more personalized therapeutic approach and to prevent the appearance of these adverse reactions. In this review, we summarize recent progresses in the Pharmacogenetics studies related to Stevens-Johnson syndrome/toxic epidermal necrolysis reporting the major genetic factors identified in the last years as associated with the disease and highlighting the use of some of these genomic variants in the clinical practice.

Ways of Narrating Memory: Hannah Arendt’s "Eichmann in Jerusalem" and Steven Spielberg’s "Schindler’s List" / Formas de narração da memória: “Eichmann em Israel”, de Hannah Arendt e “A Lista de Schindler”, de Steven Spielberg

Directory of Open Access Journals (Sweden)

Wolfgang Heuer

2012-08-01

Full Text Available Abstract It is self-evident that events of the past are bound to places and acting people, they are playing a decisive role for memory and history. Meaning and importance of places and actions in the past depend on their contexts and each change inevitably also changes the meaning of the events itself. I would like to demonstrate some of the consequences of such a change by comparing Hannah Arendt’s “Eichmann in Jerusalem“ with Steven Spielberg’s “Schindler’s List“ who decontextualized a factual story and thus changed places and acting people. But before doing this, I would like to emphasize the importance which places and acting people play for memory and history with some perhaps unusual remarks. They refer to the official European history and politics which seem to be marked by the absence of places and acting people.Keywords: Eichmann in Jerusalem, Hannah Arendt, Schindler’s List, Steven SpielbergResumo É autoevidente que acontecimentos do passado estão condicionados a lugares e a pessoas atuantes, que têm papel fundamental na memória e na história. O significado e a importância de lugares e de ações do passado dependem de seu contexto e cada mudança sua inevitavelmente altera também os próprios acontecimentos. Eu gostaria de demonstrar algumas das consequências de tal mudança comparando “Eichmann em Israel”, de Hannah Arendt com “A Lista de Schindler”, de Steven Spielberg, que descontextualizou uma história real e, assim, modificou lugares e pessoas de atuação. Mas antes disso, eu gostaria de enfatizar a importância que lugares e pessoas atuantes têm a memória e na história com alguns comentários talvez inusitados. Eles fazem referência à História oficial e à política da Europa que parecem ser marcados pela ausência de lugares e de pessoas de atuação marcante.Palavras-chaves: Eichmann em Israel, Hannah Arendt, Lista de Schindler, Steven Spielberg

Mycoplasma pneumoniae-Induced-Stevens Johnson Syndrome: Rare Occurrence in an Adult Patient

Directory of Open Access Journals (Sweden)

Samad Rasul

2012-01-01

Full Text Available Stevens-Johnson syndrome (SJS is an uncommon occurrence in Mycoplasma pneumoniae (M. pneumoniae infection (1–5% and has been mainly reported in children and young adults. We present a case of SJS in a 32-year-old male induced by M. pneumoniae infection. This patient presented with fever, cough, and massive occupation of mucus membranes with swelling, erythema, and necrosis accompanied by a generalized cutaneous rash. He clinically responded after treatment with antibiotics and IVIG. SJS is usually a drug-induced condition; however, M. pneumoniae is the commonest infectious cause and should be considered in the differential diagnosis.

Data Mining FAERS to Analyze Molecular Targets of Drugs Highly Associated with Stevens-Johnson Syndrome

OpenAIRE

Burkhart, Keith K.; Abernethy, Darrell; Jackson, David

2015-01-01

Drug features that are associated with Stevens-Johnson syndrome (SJS) have not been fully characterized. A molecular target analysis of the drugs associated with SJS in the FDA Adverse Event Reporting System (FAERS) may contribute to mechanistic insights into SJS pathophysiology. The publicly available version of FAERS was analyzed to identify disproportionality among the molecular targets, metabolizing enzymes, and transporters for drugs associated with SJS. The FAERS in-house version was al...

Erythema multiforme and Stevens-Johnson syndrome following radiotherapy

International Nuclear Information System (INIS)

Yoshitake, Tadamasa; Nakamura, Katsumasa; Shioyama, Yoshiyuki

2007-01-01

Erythema multiforme (EM) and Stevens-Johnson syndrome (SJS) are thought to be hypersensitivity syndromes with various causes, and radiotherapy might be one of the causes of these syndromes. We herein report two cases of EM/SJS following radiotherapy. The first case was a 63-year-old woman with breast cancer. At the end of postoperative radiotherapy with 60 Gy, severe pruritic erythema appeared in the irradiated area and spread over the whole body. She was diagnosed with EM by a skin biopsy. The second case was a 77-year-old woman with uterine cervical cancer who underwent postoperative radiotherapy. At a dose of 30.6 Gy, pruritic redness appeared in the irradiated area and the precordial region, and it became widespread rapidly with polymorphic transformation. Although without any histological confirmation, SJS was strongly suspected because of her pruritic conjunctivitis. Because both patients were given medicines during irradiation, radiotherapy may not be the only cause of EM/SJS. However, it should be noted that radiotherapy might trigger EM/SJS. (author)

Stevens-Johnson syndrome in patients on phenytoin and cranial radiotherapy

International Nuclear Information System (INIS)

Khafaga, Y.M.; Jamshed, A.; Allam, A.A.K.; Ezzat, A.; Gray, A.J.; Schultz, H.; Mourad, W.A.; Al Eisa, A.

1999-01-01

The use of phenytoin as a prophylactic anticonvulsant after brain surgery, particularly for brain tumors, is a common practice, regardless of whether the patient has a previous history of convulsions. This treatment policy assumes that the benefits exceed the risks. Four cases are described of adverse reactions of phenytoin during the cocomitant use of cranial radiotherapy. In one patient this proved fatal. There is increasing anecdotal support in the literature for a synergistic effect between phenytoin therapy and cranial radiotherapy that can result in the life-threatening Stevens-Johnson syndrome. While the association is uncommon, four cases within 24 months in one department suggest that the routine use of postoperative phenytoin as a prophylactic anticonvulsant in the absence of a history of seizures may not be warranted, particularly if the patient is to receive cranial radiotherapy. (orig.)

Review of The Joy of x: A Guided Tour of Math, from One to Infinity by Steven Strogatz

Directory of Open Access Journals (Sweden)

Michael T. Catalano

2014-07-01

Full Text Available Strogatz, Steven. The Joy of x: A Guided Tour of Math, from One to Infinity, (New York, NY, Houghton Mifflin Harcourt, 2012. 316 pp. ISBN 978-0-547-51765-0 The Joy of x: A Guided Tour of Math, from One to Infinity, by Steven Strogatz, is an engaging and example-filled argument for mathematics as a valuable and enjoyable activity. The thirty chapters are divided into six parts, entitled Numbers, Relationships, Shapes, Change, Data, and Frontiers. The discussion ranges from intuitive explanations of basic concepts such as place value, the four arithmetic operations, percentage increase and decrease, and solving equations, to “higher” levels of mathematics such as calculus, probability and statistics, group theory, and the nature of infinity. As in John Allen Paulos’ work, Beyond Numeracy, the chapters are short and punchy, and they can be read independently. While the book is not specifically devoted to numeracy, several chapters, especially those in Part Five on Data, address ideas and examples relevant to quantitative literacy.

Organizational Heritage and Entrepreneurship: Steven Klepper’s Theories Reflected in the Emergence and Growth of the Plastic Molds Industry in Portugal

NARCIS (Netherlands)

Costa, Carla

2015-01-01

This paper reviews the history of the emergence of the molds and plastics industries in Portugal, finding that this history fits nicely with the accounts—originally proposed in Steven Klepper’s various works—of new industries emerging from older, related industries, and regional clusters emerging

Osteo-odonto keratoprosthesis in Stevens-Johnson syndrome: a case report.

Science.gov (United States)

Sc, Reddy; I, Tajunisah; T, Tan D

2011-01-01

To report a successful osteo-odonto keratoprosthesis (OOKP) procedure in a case of end stage of corneal blindness due to Stevens-Johnson syndrome (SJS). An interventional case report. We describe a 35-year-old Indian woman, a known case of SJS with bilateral dry eyes and corneal blindness (failed corneal graft with vascularised total corneal opacity in the right eye and non-healing corneal ulcer in the left eye). Vision was hand movement only in both eyes. The corneal ulcer healed with medical treatment resulting in vascularised total corneal opacity with no improvement in vision. OOKP was performed in the right eye and the vision was improved from hand movement to 6/6. The same vision was maintained in the right eye at the last follow-up 5 years after surgery. OOKP provides good visual rehabilitation with long-term anatomically stable prosthesis in patients with end-stage of ocular surface disorders and corneal blindness secondary to SJS.

Stevens - Johnson Syndrome Induced by Combination of Lamotrigine and Valproic Acid in a 9-Year-Old Boy

LENUS (Irish Health Repository)

Maduemem, K

2017-06-01

We describe the case history of a 9-year-old boy who developed Stevens-Johnson syndrome (SJS) following concomitant use of valproic acid and lamotrigine. He presented with rash and fever several weeks after introduction of lamotrigine, having been on valproic acid for seizure disorder. SJS happens to be one of the rare adverse reactions of antiepilepsy drugs (AED). Management is mainly supportive with care escalation when necessary because of the significant morbidity.

Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis and Treatment With a Biologic: A Case Report.

Science.gov (United States)

Chong, Ian; Chao, Alice

2017-01-01

One of the most dangerous dermatologic emergencies is Stevens-Johnson Syndrome (SJS)/toxic epidermal necrolysis (TEN). Although a rare disease, it can often lead to significant mortality. In this case report, we present a 77-year-old man who developed a sloughing rash that was secondary to a nonsteroidal anti-inflammatory drug. In addition to the recommended supportive care, the patient was treated with etanercept, a new, less commonly used intervention. We provide a brief review of SJS/TEN. Nonsteroidal anti-inflammatory drugs are a rare cause of SJS/TEN, and additionally, the use of biologics is a novel treatment modality for SJS/TEN.

Steven johnsons syndrome and toxic epidermal necrolysis: A review

Directory of Open Access Journals (Sweden)

Sri ram Anne

2014-12-01

Full Text Available Toxic epidermal necrolysis (TEN and Stevens Johnson Syndrome (SJS are severe adverse cutaneous drug reactions that predominantly involve the skin and mucous membranes. They are characterized by mucocutaneous tenderness and typically hemorrhagic erosions, erythema and more or less severe epidermal detachment presenting as blisters and areas of denuded skin. Drugs are assumed or identified as the main cause of SJS/TEN in most cases, but Mycoplasma pneumoniae and Herpes simplex virus infections are well documented causes alongside rare cases in which the etiology remains unknown. Several drugs are at "high" risk of inducing TEN/SJS including: Allopurinol, Trimethoprim-sulfamethoxazole and other sulfonamide-antibiotics, aminopenicillins, cephalosporins, quinolones, carbamazepine, phenytoin, phenobarbital and NSAID's of the oxicam-type. Differential diagnosis includes linear IgA dermatosis and paraneoplastic pemphigus, pemphigus vulgaris and bullous pemphigoid, acute generalized exanthematous pustulosis (AGEP, disseminated fixed bullous drug eruption and staphyloccocal scalded skin syndrome (SSSS. Due to the high risk of mortality, management of patients with SJS/TEN requires rapid diagnosis, identification and interruption of the culprit drug, specialized supportive care ideally in an intensive care unit, and consideration of immunomodulating agents such as high-dose intravenous immunoglobulin therapy.

Síndrome de Stevens-Johnson e necrólise epidérmica tóxica

OpenAIRE

Coelho, Inês Dionísio

2013-01-01

Trabalho final de mestrado integrado em Medicina (Dermatologia), apresentado à Faculdade de Medicina da Universidade de Coimbra. A Síndrome de Stevens-Johnson (SSJ) e a necrólise epidérmica tóxica (NET) são reacções mucocutâneas raras consideradas emergências médicas, podendo tornar-se fatais. Constituem dois extremos do mesmo espectro clínico das reacções cutâneas severas adversas a fármacos com necrose epidérmica, diferindo apenas na extensão do descolamento epidérmico. A gra...

Från outsiderfilmmakare till etablerad indieregissör : David Lynch, Jim Jarmusch och Steven Soderbergh

OpenAIRE

Simberg, Maximilian

2014-01-01

Det här arbetet behandlar kreativ frihet och konstnärligt oberoende i filmskapande, utgående från begreppet independent film och regissörerna David Lynch, Jim Jarmusch och Steven Soderbergh. Den centrala frågeställningen är hur det har varit möjligt för en filmkonstnär att uppnå konstnärligt oberoende och samtidigt ha en långlivad och framgångsrik karriär. Arbetets fokus ligger på de tre regissörernas genombrottsfilmer; Eraserhead, Stranger Than Paradise och sex, lies, and videotape, och förs...

Milliste plaanidega lähed vastu uuele õppeaastale? / Triinu Lepp, Gleb Tšurbanov, Erik Paemurru, Steven Huang...[jt.

Index Scriptorium Estoniae

2008-01-01

Küsimusele vastavad hariduskolleegiumi algkooli 3. klassi õpilane Egert, prantsuse lütseumi 12. klassi õpilane Triinu Lepp, Sillamäe kutsekooli 3. kursuse õpilane Gleb Tšurbanov, Tallinna reaalkooli 11. klassi õpilane Erik Paemurru, Toronto Crescenti keskkooli õpilane Steven Huang, kunstiakadeemia muinsuskaitse- ja restaureerimisosakonna õppejõud Jaan Tamm, Tartu Miina Härma gümnaasiumi 2. a klassi õpilane Erki Külaots, Tallinna 21. kooli 11. klassi õpilane Sander Kaur ja Tapa gümnaasiumi 7. klassi õpilane Evelin Orgse

High Level Human Herpesvirus-6 Viremia Associated with onset of Stevens-Johnson Syndrome: Report of 2 Cases

Science.gov (United States)

Peppercorn, Amanda F.; Miller, Melissa B.; Fitzgerald, David; Weber, David J.; Groben, Pamela A.; Cairns, Bruce A.

2015-01-01

The pathogenesis of Stevens Johnson Syndrome (SJS) remains obscure but it has been associated with various infectious agents, including members of the Herpes virus family. We present the first report of high level human herpesvirus-6 (HHV-6) viremia at the onset of SJS suggesting a possible new association. This finding supports the need for further investigation into the possible relationship between HHV-6 and SJS which may illuminate the pathogenesis of SJS and bring us closer to achieving enhanced prevention and treatment of this rare disease. PMID:20182379

Irradiated fields spared Stevens-Johnson syndrome in a patient undergoing radiotherapy for bone metastases

International Nuclear Information System (INIS)

Musio, D.; Parisi, E.; Dionisi, F.

2009-01-01

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two of the most severe, rare, and life-threatening adverse reactions to medications. Their incidence is approximately two patients per million population per year. Several cases have been reported in the literature in which SJS and TEN have occurred in patients with a neoplasm undergoing radiation therapy and who are taking an anticonvulsant. We report a case of SJS-TEN that developed in a 51-year-old woman with nonresectable non-small-cell lung cancer during treatment with phenobarbital plus radiation therapy for bone metastases but in whom the irradiated areas did not exhibit the SJS skin reaction. To our knowledge, no similar cases have been reported in the literature. (author)

Comprehensive approach to ocular consequences of Stevens Johnson Syndrome - the aftermath of a systemic condition.

Science.gov (United States)

Iyer, Geetha; Srinivasan, Bhaskar; Agarwal, Shweta; Kamala Muralidharan, Seema; Arumugam, Sumathi

2014-03-01

Stevens Johnson Syndrome (SJS) can lead to end stage corneal blindness. This study describes the comprehensive treatment measures and their outcomes in the management of ocular sequelae and complications of SJS. Four hundred sixty-four eyes of 232 patients of SJS who underwent surgical intervention (punctal cautery, mucus membrane grafting for lid margin keratinisation, fornix reconstructive procedures, tectonic procedures, keratoplasty and keratoprosthesis) were studied. It was a non-comparative, retrospective, interventional case series. The primary outcome was the change in the best corrected visual acuity (BCVA). Secondary outcome measures included an improvement in the ocular surface status as indicated by corneal epithelial fluorescein staining and Schirmer's I strip wetting. The BCVA and the ocular surface status improved and/or stabilized in > 70 % of eyes following punctal cautery (n = 160) and > 80 % of eyes following lid margin mucus membrane grafting (n = 238). BCVA improved in 50 % of eyes following fornix reconstructive procedures (n = 24) with COMET (n = 6), in 63.9 % eyes with the Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) lens (n = 36), in 81.8 % of eyes after cataract surgery (n = 22). A BCVA of ≥20/200 was achieved in 72.34 % of eyes following keratoprostheses procedures (n = 47). The mean duration of follow up was 53.3 ± 15.2 months. The ocular sequelae of Stevens Johnson Syndrome can be blinding. They need to be identified and addressed early to retard the continued deterioration of the ocular surface. Our study aims to highlight the problem as well as the importance of comprehensive measures in the management of this potentially blinding disorder.

Stevens-Johnson Syndrome Induced by Carbamazepine Treatment in a Patient Who Previously Had Carbamazepine Induced Pruritus - A Case Report -

OpenAIRE

Bae, Hyun Min; Park, Yoo Jung; Kim, Young Hoon; Moon, Dong Eon

2013-01-01

Stevens-Johnson syndrome (SJS) is a rare but life-threatening skin reaction disease and carbamazepine is one of its most common causes. We report a case of SJS secondary to carbamazepine in a patient with previous pruritus due to carbamazepine which was given for treatment of trigeminal neuralgia. We would like to caution all providers that carbamazepine readministration should be avoided in the patient with a previous history of SJS or adverse skin reaction. In addition, we strongly recommen...

Erythema multiforme and Stevens-Johnson syndrome in patients receiving cranial irradiation and phenytoin

International Nuclear Information System (INIS)

Delattre, J.Y.; Safai, B.; Posner, J.B.

1988-01-01

In 15 months we encountered eight patients with intracranial tumors who developed erythema multiforme (EM) or erythema multiforme bullosa (Stevens-Johnson syndrome). All occurred shortly after use of phenytoin (DPH) and brain radiation therapy (WBRT). The clinical picture differed from the classic form of EM in that the erythema began on the scalp and spread to the extremities, progressing in three cases to extensive bullous formation. There were no cases of EM among patients who received either DPH or radiotherapy alone. The combination of DPH, WBRT, and tapering of steroids seems to predispose to EM. The pathogenesis of the disorder is probably immunologic. In the absence of seizures, anticonvulsants should not be given routinely to patients with brain tumors. When anticonvulsants are necessary in patients scheduled for WBRT, DPH may not be the drug of choice

Honoring the work and life of Leroy C. Stevens. A symposium as part of the International Stem Cell Initiative Workshop.

Science.gov (United States)

Graham, Christopher F; Solter, Davor; Gearhart, John D; Nadeau, Joseph H; Knowles, Barbara B

2016-01-01

In 2016, a symposium was convened in Leroy C. Stevens' honor, in association with a meeting of the International Stem Cell Initiative (ISCI). ISCI, funded internationally, is composed of a group of ~100 scientists from many countries, under the leadership of Peter Andrews, who have worked together to characterize a significant number of human pluripotent stem cell lines, to monitor their genetic stability and their differentiation into mature cell types and tissues in vitro and in vivo. Those at the ISCI meeting puzzled through one of the thorniest problems in the therapeutic use of the differentiated derivatives of pluripotent stem cells for human therapy; namely, pluripotent stem cells can differentiate into any cell type in the adult organism, but they also have the capacity for unlimited self-renewal, hence if mutated they may have tumorigenic potential. The meeting considered how these cells might become genetically or epigenetically abnormal and how the safety of these cells for human therapeutic uses could be assessed and assured. The symposium was an opportunity to pay tribute to Leroy Stevens and to the basic science origins of this newest aspect of regenerative medicine. It was a time to reflect on the past and on how it can influence the future of our field.

Bicycles, Airplanes and Peter Pans: Flying Scenes in Steven Spielberg's Films

Directory of Open Access Journals (Sweden)

Emilio Audissino

2014-10-01

Full Text Available In Steven Spielberg's cinema the flight is a recurring theme. Flying scenes can be sorted into two classes: those involving a realistic flight – by aircraft – and those involving a magical flight – by supernatural powers. The realistic flight is influenced by the war stories of Spielberg's father – a radio man in U.S. Air-force during WWII – and it is featured in such films as Empire of the Sun (1987, Always (1989, and 1941 (1979. The magical flight is influenced by James M. Barries' character Peter Pan (Peter and Wendy, 1911, which is quoted directly in E.T. the Extraterrestrial (1982 and, above all, in Hook (1991, which is a sequel to Barrie's story. These two types of flying scenes are analysed as to their meanings, compared to the models that influenced them, and surveyed as to their evolution across Spielberg's films. A central case study is the episode The Mission from Amazing Stories (1985, in which the realistic and the magical flights overlap.

Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Concise Review with a Comprehensive Summary of Therapeutic Interventions Emphasizing Supportive Measures

OpenAIRE

Schneider, Jeremy A.; Cohen, Philip R.

2017-01-01

Introduction Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two of the most severe dermatologic conditions occurring in the inpatient setting. There is a lack of consensus regarding appropriate management of SJS and TEN. Purpose The scientific literature pertaining to SJS and TEN (subsequently referred to as SJS/TEN) is summarized and assessed. In addition, an interventional approach for the clinician is provided. Methods PubMed was searched with the key words: cortic...

Stereoselective synthesis of functionalized cyclic amino acid derivatives via a [2,3]-Stevens rearrangement and ring-closing metathesis.

Science.gov (United States)

Nash, Aaron; Soheili, Arash; Tambar, Uttam K

2013-09-20

Unnatural cyclic amino acids are valuable tools in biomedical research and drug discovery. A two-step stereoselective strategy for converting simple glycine-derived aminoesters into unnatural cyclic amino acid derivatives has been developed. The process includes a palladium-catalyzed tandem allylic amination/[2,3]-Stevens rearrangement followed by a ruthenium-catalyzed ring-closing metathesis. The [2,3]-rearrangement proceeds with high diastereoselectivity through an exo transition state. Oppolzer's chiral auxiliary was utilized to access an enantiopure cyclic amino acid by this approach, which will enable future biological applications.

Steven E. Miller and Dmitri V. Trenin, eds., The Russian Military: Power and Policy, Cambridge, MA: MIT Press, 2004.

Directory of Open Access Journals (Sweden)

Mikhail Tsypkin

2005-10-01

Full Text Available The Russian military largely went below the radar of Western interest after the disintegration of the Soviet Union.  More than a decade after the creation of the Armed Forces of the Russian Federation, they have become again the object of interest for scholars – this time, both Western and Russian, as demonstrated by the reviewed volume, whose editors assembled a group of extraordinarily knowledgeable experts from Russia and the West.  In his introduction, Steven Miller explains that the purp...

Comparison of the U-233 dog data of Stevens et al. with uranium retention functions in ICRP Publication 30 and a 3-compartment mammillary model for uranium

International Nuclear Information System (INIS)

Bernard, S.R.

1983-01-01

Stevens measured the distribution, retention, and excretion of U-233 in seven beagles each given a single injection of U-233 citrate [2.8 μCi/kg U-233 (VI) (approx.3 mg/dog)]. These data, when plotted together with results obtained with the ICRP (Pub. 30) retention functions for purposes of comparison, are seen to differ only slightly from the ICRP-30 model. The number of transformations in the body, over a fifty-year period agree within a factor of 2. A three-compartment mammillary model has been parameterized from the data of Stevens by the method of Bernard. Retention in tissues of the body is represented by a linear combination of three compartments. The data plots for the dogs and ICRP-30 model will be presented and discussed together with the three compartment mammillary model for U-233 retention, distribution, and excretion. 3 figs., 2 tabs

Mucous membrane grafting for the post-Steven-Johnson syndrome symblepharon: A case report

Directory of Open Access Journals (Sweden)

Jayanta Kumar Das

2011-01-01

Full Text Available An 18-year-old woman was referred with late sequelae of chloroquine-induced Steven-Johnson syndrome. At the time of presentation, the symblepharon was involving the upper lids to almost the whole of the cornea, and part of the lower bulbar conjunctiva with the lower lid bilaterally. Other ocular examinations were not possible due to the symblepharon. B-scan ultrasonography revealed acoustically clear vitreous, normal chorioretinal thickness, and normal optic nerve head, with an attached retina. Conjunctivo-corneal adhesion released by superficial lamellar dissection of the cornea. Ocular surface reconstruction was carried out with a buccal mucous membrane. A bandage contact lens was placed over the cornea followed by the symblepharon ring to prevent further adhesion. The mucosal graft was well taken up along with corneal re-epithelization. Best corrected visual acuity of 20/120 in both sides after 1 month and 20/80 after 3 months was achieved and maintained till the 2.5-year follow-up.

Association of HLA-BFNx011502 allele and carbamazepine-induced Stevens-Johnson syndrome among Indians

Directory of Open Access Journals (Sweden)

Mehta Timir

2009-01-01

Full Text Available Background: Stevens-Johnson Syndrome (SJS and toxic epidermal necrolysis are severe cutaneous reactions caused by certain drugs, including antiepileptic carbamazepine. A strong association has been reported between human leucocyte antigen (HLA-BFNx011502 and carbamazepine-induced SJS in Han Chinese patients. European studies suggested that HLA-BFNx011502 is not a universal marker but is ethnicity-specific for Asians. Aim: To study the association between HLA-BFNx011502 and carbamazepine-induced SJS in Indian patients. Methods: Eight individuals who fulfilled the diagnostic criteria of SJS induced by carbamazepine were identified and HLA-B molecular typing was performed. HLA-B genotyping was carried out by polymerase chain reaction using sequence-specific primers. Results: Out of eight patients studied for genotype, six patients were found to have the HLA-BFNx011502 allele. Conclusion: This study suggests an association between HLA-BFNx011502 and carbamazepine-induced SJS in Indian patients.

Areas of Agreement and Disagreement Regarding Ponderosa Pine and Mixed Conifer Forest Fire Regimes: A Dialogue with Stevens et al.

Directory of Open Access Journals (Sweden)

Dennis C Odion

Full Text Available In a recent PLOS ONE paper, we conducted an evidence-based analysis of current versus historical fire regimes and concluded that traditionally defined reference conditions of low-severity fire regimes for ponderosa pine (Pinus ponderosa and mixed-conifer forests were incomplete, missing considerable variability in forest structure and fire regimes. Stevens et al. (this issue agree that high-severity fire was a component of these forests, but disagree that one of the several sources of evidence, stand age from a large number of forest inventory and analysis (FIA plots across the western USA, support our findings that severe fire played more than a minor role ecologically in these forests. Here we highlight areas of agreement and disagreement about past fire, and analyze the methods Stevens et al. used to assess the FIA stand-age data. We found a major problem with a calculation they used to conclude that the FIA data were not useful for evaluating fire regimes. Their calculation, as well as a narrowing of the definition of high-severity fire from the one we used, leads to a large underestimate of conditions consistent with historical high-severity fire. The FIA stand age data do have limitations but they are consistent with other landscape-inference data sources in supporting a broader paradigm about historical variability of fire in ponderosa and mixed-conifer forests than had been traditionally recognized, as described in our previous PLOS paper.

Areas of Agreement and Disagreement Regarding Ponderosa Pine and Mixed Conifer Forest Fire Regimes: A Dialogue with Stevens et al.

Science.gov (United States)

Odion, Dennis C; Hanson, Chad T; Baker, William L; DellaSala, Dominick A; Williams, Mark A

2016-01-01

In a recent PLOS ONE paper, we conducted an evidence-based analysis of current versus historical fire regimes and concluded that traditionally defined reference conditions of low-severity fire regimes for ponderosa pine (Pinus ponderosa) and mixed-conifer forests were incomplete, missing considerable variability in forest structure and fire regimes. Stevens et al. (this issue) agree that high-severity fire was a component of these forests, but disagree that one of the several sources of evidence, stand age from a large number of forest inventory and analysis (FIA) plots across the western USA, support our findings that severe fire played more than a minor role ecologically in these forests. Here we highlight areas of agreement and disagreement about past fire, and analyze the methods Stevens et al. used to assess the FIA stand-age data. We found a major problem with a calculation they used to conclude that the FIA data were not useful for evaluating fire regimes. Their calculation, as well as a narrowing of the definition of high-severity fire from the one we used, leads to a large underestimate of conditions consistent with historical high-severity fire. The FIA stand age data do have limitations but they are consistent with other landscape-inference data sources in supporting a broader paradigm about historical variability of fire in ponderosa and mixed-conifer forests than had been traditionally recognized, as described in our previous PLOS paper.

Ernest Orlando Lawrence Awards Ceremony for 2011 Award Winners (Presentations, including remarks by Energy Secretary, Dr. Steven Chu)

International Nuclear Information System (INIS)

Chu, Steven

2012-01-01

The winners for 2011 of the Department of Energy's Ernest Orlando Lawrence Award were recognized in a ceremony held May 21, 2012. Dr. Steven Chu and others spoke of the importance of the accomplishments and the prestigious history of the award. The recipients of the Ernest Orlando Lawrence Award for 2011 are: Riccardo Betti (University of Rochester); Paul C. Canfield (Ames Laboratory); Mark B. Chadwick (Los Alamos National Laboratory); David E. Chavez (Los Alamos National Laboratory); Amit Goyal (Oak Ridge National Laboratory); Thomas P. Guilderson (Lawrence Livermore National Laboratory); Lois Curfman McInnes (Argonne National Laboratory); Bernard Matthew Poelker (Thomas Jeffereson National Accelerator Facility); and Barry F. Smith (Argonne National Laboratory).

Steven Pinker. The Better Angels of Our Nature. Why violence has declined. Viking Adult, New York, 2011, 832 p.

OpenAIRE

Jairo Antonio Melo Flórez

2011-01-01

Aunque ya es una tesis bastante aceptada por los historiadores y sociólogos, la posibilidad de que, al contrario de la creencia popular, vivamos en tal vez una de las épocas más pacíficas de la historia es aún controvertida, más aún cuando llega un trabajo de una de las figuras públicas de la academia como es el profesor de Harvard Steven Pinker. Sin embargo, Pinker se había dedicado a psicología cognitiva y ganó fama al presentar al lenguaje como un instinto de la humanidad, y más aún al pre...

Toxic epidermal necrolysis and Stevens-Johnson syndrome

Directory of Open Access Journals (Sweden)

French Lars E

2010-12-01

Full Text Available Abstract Toxic epidermal necrolysis (TEN and Stevens Johnson Syndrome (SJS are severe adverse cutaneous drug reactions that predominantly involve the skin and mucous membranes. Both are rare, with TEN and SJS affecting approximately 1or 2/1,000,000 annually, and are considered medical emergencies as they are potentially fatal. They are characterized by mucocutaneous tenderness and typically hemorrhagic erosions, erythema and more or less severe epidermal detachment presenting as blisters and areas of denuded skin. Currently, TEN and SJS are considered to be two ends of a spectrum of severe epidermolytic adverse cutaneous drug reactions, differing only by their extent of skin detachment. Drugs are assumed or identified as the main cause of SJS/TEN in most cases, but Mycoplasma pneumoniae and Herpes simplex virus infections are well documented causes alongside rare cases in which the aetiology remains unknown. Several drugs are at "high" risk of inducing TEN/SJS including: Allopurinol, Trimethoprim-sulfamethoxazole and other sulfonamide-antibiotics, aminopenicillins, cephalosporins, quinolones, carbamazepine, phenytoin, phenobarbital and NSAID's of the oxicam-type. Genetic susceptibility to SJS and TEN is likely as exemplified by the strong association observed in Han Chinese between a genetic marker, the human leukocyte antigen HLA-B*1502, and SJS induced by carbamazepine. Diagnosis relies mainly on clinical signs together with the histological analysis of a skin biopsy showing typical full-thickness epidermal necrolysis due to extensive keratinocyte apoptosis. Differential diagnosis includes linear IgA dermatosis and paraneoplastic pemphigus, pemphigus vulgaris and bullous pemphigoid, acute generalized exanthematous pustulosis (AGEP, disseminated fixed bullous drug eruption and staphyloccocal scalded skin syndrome (SSSS. Due to the high risk of mortality, management of patients with SJS/TEN requires rapid diagnosis, evaluation of the prognosis

Q&A with Steven Spencer: Speaker in the Women and STEM Series Talks About How He Became Interested in Studying Psychology, Dissonance, and Stereotype Threat

OpenAIRE

Hooker, Courtney

2011-01-01

As I talked with Steven Spencer, Professor at the University of Waterloo and a groundbreaking researcher in the field of stereotype threat, I was impressed by his kind demeanor and effective speaking style. He shared information about his academic career, advice for graduate students as well as discussing this research on how to dismantle the negative stereotypes that inhibit women’s progression in science, technology, engineering, and math fields (STEM).

Contemporary perspectives in aesthetic theory: Steven Connor, Sianne Ngai and the edible world

Directory of Open Access Journals (Sweden)

Tom Lee

2016-07-01

Full Text Available This article interprets the work of cultural theorists Steven Connor and Sianne Ngai in terms of their efforts to reevaluate certain key presumptions of aesthetic theory that inherits the surprisingly resilient biases of the 18th century, in particular the work of Immanuel Kant and Edmund Burke. Focusing on the work of Ngai and Connor, I think through the implications this recent theory has for the previously peripheral position occupied by gustatory taste and the cultural objects and experiences it implicates. I discuss the possibility that ideas and examples drawn from the work of Connor and Ngai might form the basis for an alternative area of analysis that is better adapted to the peculiarities of gustatory taste and the culinary. In particular, I argue that the visceral element, which tends to accompany gustatory taste, ought to be interpreted in terms of its generative contribution to the creation of concepts through metaphor, rather than as a muddying influence that prevents clarity of discrimination. Similarly, the close relationship between the edible and the domestic is deserving of a more generous reading than is commonly found in aesthetic theory underwritten by the categories of the sublime and the beautiful.

Two new tropolonic alkaloids from Colchicum speciosum Steven bulbs

Directory of Open Access Journals (Sweden)

S. Tayyeb*

2017-11-01

Full Text Available Background and objectives: The genus Colchicum belongs to the family Colchicaceae, which comprises of 19 genera, and 225 species worldwide. They have been recognized for more than 2000 years for their noticeable biological properties. The Colchicum species are well known for presence of tropolonic alkaloids, mainly colchicine. Colchicine, is still the drug of choice for treatment of gout, and is used for the treatment of a number of proinflammatory disorders, such as familial Mediterranean fever, and Behcet’s disease. Clinical studies have proved colchicine to posses potent anti-tumor activity. Colchicum speciosum Steven is an indigenous perennial herbaceous plant widely distributed in northern, central and western regions of Iran.  Methods: In the present study, the phytochemical composition of MeOH extract from bulbs of C. speciosum collected fromSavadkouh region, Iranwas investigated by combination of HPLC-PDA-MS spectrometry and NMR specroscopy. The fractionation of MeOH extract was carried out by partitioning on CH2Cl2, EtOAc and water. Results: The isolation and purification of CH2Cl2 portion by combination of reverse and normal phase chromatography resulted in the isolation, purification and identification of two new tropolonic alkaloids, compounds (1 and (2, as well as two known compound colchicine (3 and demecolcine (4. Their structures were established by extensive spectroscopic methods, including 1D (1H NMR and 2D-NMR (COSY, HSQC and HMBC. The absolute configurations of isolated compounds were established by aid of circular dichroism. Conclusion: Phytochemical investigation of CH2Cl2 extract of C. speciosum by combination of HPLC, column chromatography and hyphenated spectroscopic techniques led to identification two new alkaloids with potential as lead compounds.

Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Concise Review with a Comprehensive Summary of Therapeutic Interventions Emphasizing Supportive Measures.

Science.gov (United States)

Schneider, Jeremy A; Cohen, Philip R

2017-06-01

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two of the most severe dermatologic conditions occurring in the inpatient setting. There is a lack of consensus regarding appropriate management of SJS and TEN. The scientific literature pertaining to SJS and TEN (subsequently referred to as SJS/TEN) is summarized and assessed. In addition, an interventional approach for the clinician is provided. PubMed was searched with the key words: corticosteroids, cyclosporine, etanercept, intravenous immunoglobulin, Stevens-Johnson syndrome, and toxic epidermal necrolysis. The papers generated by the search, and their references, were reviewed. Supportive care is the most universally accepted intervention for SJS/TEN. Specific guidelines differ from the care required for patients with thermal burns. Adjuvant therapies are utilized in most severe cases, but the data are thus far underwhelming and underpowered. Using systemic corticosteroids as sole therapy is not supported. A consensus regarding combined corticosteroids and intravenous immunoglobulin (IVIG) has not been reached. Data regarding IVIG, currently the standard of care for most referral centers, is conflicting. Newer studies regarding cyclosporine and tumor necrosis factor inhibitors are promising, but not powered to provide definitive evidence of efficacy. Data regarding plasmapheresis is equivocal. Thalidomide increases mortality. Clinicians who manage SJS/TEN should seek to employ interventions with the greatest impact on their patients' condition. While supportive care measures may seem an obvious aspect of SJS/TEN patient care, providers should understand that these interventions are imperative and that they differ from the care recommended for other critically ill or burn patients. While adjuvant therapies are frequently discussed and debated for hospitalized patients with SJS/TEN, a standardized management approach is not yet clear based on the current data. Therefore, until further data

The Epidemiology of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in China

Directory of Open Access Journals (Sweden)

Shang-Chen Yang

2018-01-01

Full Text Available Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN are life-threatening disease. However, there are only few epidemiologic studies of SJS/TEN from China. To analyze the clinical characteristics, causality, and outcome of treatment for SJS/TEN in China, we reviewed case reports of patients with SJS/TEN from the China National Knowledge Infrastructure (CNKI and Wanfang database from 2006 to 2016 and patients with SJS/TEN who were admitted to the First Affiliated Hospital of Fujian Medical University during the same period. There were 166 patients enrolled, including 70 SJS, 2 SJS/TEN overlap, and 94 TEN. The most common offending drugs were antibiotics (29.5% and anticonvulsants (24.1%. Carbamazepine, allopurinol, and penicillins were the most common single offending drugs (17.5%, 9.6%, and 7.2%. Chinese patent medicines accounted for 5.4%. There were 76 (45.8% patients receiving systemic steroid and intravenous immunoglobulin (IVIG in combination therapy, especially for TEN (80.3%, and others were treated with systemic steroids alone. Mortality rate of combination treatment comparing with steroid alone in TEN patients had no statistical significance. In conclusion, carbamazepine and allopurinol were the leading causative drugs for SJS/TEN in China. Combination of IVIG and steroids is a common treatment for TEN, but its efficacy in improving mortality needs further investigation.

Representations of nurses and individuals in psychological distress in the photographic exhibit USAnatomy, by Steven Klein.

Science.gov (United States)

Carvalho, Evanilda Souza de Santana; Araújo, Edna Maria de; Santos, Silvone Santa Bárbara da Silva; Santos, Alexandro Gesner Gomes Dos

2016-06-01

Objectives To analyze the representations of the nurse and individual in mental suffering portrayed in the photographic work by Steven Klein, in the USAnatomy exhibit held at the Museum of Sculpture (Museu da escultura) in São Paulo, in 2011. Methods Qualitative study carried out in 2012. Three photographs were submitted to iconographic analysis. The interpretation of the findings was based on theoretical frameworks of Foucault and Bourdieu on power relations. Results The nurse is represented as a sensual, insensitive person, with the power to control and torture while the person in psychological distress is represented as dirty, imprisoned and subjected to an asymmetrical relationship of power with the nurse. Final considerations Relationships of submission and symbolic dominance, in which the person in psychological distress has their body molded by discipline imposed by the nurse. Stereotypes of the image of the nurse oppose the ideology of the profession, which is to ensure the integrity of those being cared for.

“Inspired by real events”—Media (and Memory in Steven Spielberg’s MUNICH (2005

Directory of Open Access Journals (Sweden)

Thomas Nachreiner

2016-02-01

Full Text Available Steven Spielberg’s 2005 film Munich tells the story of an Israeli counter-terrorist team in the aftermath of the hijacking and massacre at the Olympic Games in 1972. The film spawned broad discussion about its historical accuracy and its political standpoint. While criticism primarily focused on the historiographical representation of the actions depicted, this paper analyzes in two steps the genuinely filmic mode of historical representation ofMunich. First, the analysis discusses the interplay of two conflicting narrative strategies that negotiate the character development with the political struggle. And second, analysis focuses on the two formal devices at the core of the narrative conflict: The reflexive framing of television in the depiction of the Munich massacre as a traumatic media event and the excessive transformation of its memory in a series of flashbacks. Such elaboration of the narrative and formal strategies reveals the implicit historiographical structures of the film and suggests that the notion of ‘cultural trauma’ serves as the preferential—but problematic—template in telling the history of terrorism and violence.

Analysis of Body Constitution of Fifty-two Patients with Stevens-Johnson Syndrome (SJS) Using Kampo Medical Questionnaires: Prediction of SJS based on Body Constitution Using Decision Tree

OpenAIRE

大嶋, 繁; 羽鳥, 有紀子; 本間, 精一; 寺澤, 捷年; 齋藤, 侑也; 小林, 大介

2011-01-01

Reports have indicated a relationship between adverse drug reaction (ADR) and Human Leukocyte Antigen (HLA) polymorphism and a relationship between Body Constitution (BC) and HLA polymorphism. Thus, a relationship between ADR and BC is suggested. We therefore created a questionnaire (hereinafter “Questionnaire”) to survey the typical BC of Stevens-Johnson Syndrome (SJS) patients to determine how they differ from healthy persons, and studied the relationship between the development of SJS and ...

Clinical Features and Treatment Outcomes among Children with Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A 20-Year Study in a Tertiary Referral Hospital

OpenAIRE

Susheera Chatproedprai; Vanvara Wutticharoenwong; Therdpong Tempark; Siriwan Wananukul

2018-01-01

Aim. To determine the probable causative factors, clinical features, and treatment outcomes of Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS-TEN overlap in children. Methods. A 20-year database review of all children diagnosed with SJS/TEN/SJS-TEN overlap at the King Chulalongkorn Memorial Hospital, Thailand. Results. 36 patients (M : F, 16 : 20) with the mean age of 9.2±4.0 years were identified. There were 20 cases of SJS, 4 cases of SJS-TEN overlap, and 12 cases...

Steven Pinker. The Better Angels of Our Nature. Why violence has declined. Viking Adult, New York, 2011, 832 p.

Directory of Open Access Journals (Sweden)

Jairo Antonio Melo Flórez

2011-05-01

Full Text Available Aunque ya es una tesis bastante aceptada por los historiadores y sociólogos, la posibilidad de que, al contrario de la creencia popular, vivamos en tal vez una de las épocas más pacíficas de la historia es aún controvertida, más aún cuando llega un trabajo de una de las figuras públicas de la academia como es el profesor de Harvard Steven Pinker. Sin embargo, Pinker se había dedicado a psicología cognitiva y ganó fama al presentar al lenguaje como un instinto de la humanidad, y más aún al presentar sus resultados en libros dirigidos al público en general, algo bastante común entre los científicos norteamericanos.

Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis--A Comprehensive Review and Guide to Therapy. I. Systemic Disease.

Science.gov (United States)

Kohanim, Sahar; Palioura, Sotiria; Saeed, Hajirah N; Akpek, Esen K; Amescua, Guillermo; Basu, Sayan; Blomquist, Preston H; Bouchard, Charles S; Dart, John K; Gai, Xiaowu; Gomes, José A P; Gregory, Darren G; Iyer, Geetha; Jacobs, Deborah S; Johnson, Anthony J; Kinoshita, Shigeru; Mantagos, Iason S; Mehta, Jodhbir S; Perez, Victor L; Pflugfelder, Stephen C; Sangwan, Virender S; Sippel, Kimberly C; Sotozono, Chie; Srinivasan, Bhaskar; Tan, Donald T H; Tandon, Radhika; Tseng, Scheffer C G; Ueta, Mayumi; Chodosh, James

2016-01-01

The intent of this review is to comprehensively appraise the state of the art with regard to Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), with particular attention to the ocular surface complications and their management. SJS and TEN represent two ends of a spectrum of immune-mediated, dermatobullous disease, characterized in the acute phase by a febrile illness followed by skin and mucous membrane necrosis and detachment. The widespread keratinocyte death seen in SJS/TEN is rapid and irreversible, and even with early and aggressive intervention, morbidity is severe and mortality not uncommon. We have divided this review into two parts. Part I summarizes the epidemiology and immunopathogenesis of SJS/TEN and discusses systemic therapy and its possible benefits. We hope this review will help the ophthalmologist better understand the mechanisms of disease in SJS/TEN and enhance their care of patients with this complex and often debilitating disease. Part II (April 2016 issue) will focus on ophthalmic manifestations. Copyright © 2016 Elsevier Inc. All rights reserved.

Stevens Johnson syndrome, toxic epidermal necrolysis and SJS-TEN overlap: A retrospective study of causative drugs and clinical outcome

Directory of Open Access Journals (Sweden)

Sharma Vinod

2008-01-01

Full Text Available Background and Aims: Stevens Johnson syndrome (SJS, toxic epidermal necrolysis (TEN and SJS-TEN overlap are serious adverse cutaneous drug reactions. Drugs are often implicated in these reactions. Methods: A retrospective analysis of inpatients′ data with these dermatological diagnoses were carried out for three years, to study the causative drugs, clinical outcome, and mortality in these conditions. Results: Thirty patients (15 TEN, nine SJS-TEN overlap, and six SJS were admitted. In 21 cases, multiple drugs were implicated whereas single drugs were responsible in nine. Anticonvulsants (35.08% were the most commonly implicated drugs followed by antibiotics (33.33% and NSAIDS (24.56%. Twenty-five patients recovered whereas five died (four TEN, one SJS-TEN overlap. Conclusion: Anticonvulsants, antibiotics and NSAIDs were the most frequently implicated drugs. TEN causes higher mortality than both SJS and SJS-TEN overlap.

L’art du vitrail en France au temps de la reconstruction et de la croissance. Note sur les fonds Hébert-Stevens - Bony conservés aux Archives nationales du monde du travail (Fonds n° 2002 001

Directory of Open Access Journals (Sweden)

Christian Hottin

2009-11-01

Full Text Available Cet article a pour objet de présenter brièvement le fonds de l’atelier Hébert-Stevens - Bony, entré aux Archives nationales (Archives nationales du monde du travail, Roubaix en 2002

Genetic Markers and Danger Signals in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

Directory of Open Access Journals (Sweden)

Wen-Hung Chung

2010-01-01

Full Text Available Stevens-Johnson syndrome (SJS and toxic epidermal necrolysis (TEN are life-threatening adverse reactions, which could be induced by a variety of drugs. It was proposed that human leukocyte antigen (HLA-restricted presentation of antigens (drugs or their metabolites to T lymphocytes initiates the immune reactions of SJS/ TEN. However, the genetic susceptibility and the exact pathogenesis were not clear until the recent studies. We first identified that HLA-B*1502 is strongly associated with carbamazepine (CBZ-induced SJS/TEN and HLA-B*5801 with allopurinol-SJS/TEN in Han Chinese. The same associations had been validated across different human populations. For the downstream danger signals, Fas-Fas ligand (FasL and perforin/granzyme B had been advocated as cytotoxic mediators for keratinocyte death in SJS/TEN. However, expression levels of these cytotoxic proteins from the skin lesions were too low to explain the distinct and extensive epidermal necrosis. Our recent study identified that the granulysin, a cytotoxic protein released from cytotoxic T cells or natural killer (NK cells, is a key mediator for disseminated keratinocyte death in SJS/TEN. This article aims to provide an overview of both of the genomic and immunologic perspectives of SJS/TEN. These studies give us a better understanding of the immune mechanisms, biomarkers for disease prevention and early diagnosis, as well as providing the therapeutic targets for the treatments of SJS/TEN.

Genotipificación de HLA-B en pacientes colombianos afectados por el síndrome Stevens-Johnson y la Necrólisis Epidérmica Tóxica

OpenAIRE

León Ruiz, Maria Juliana

2014-01-01

Las reacciones alérgicas a medicamentos cutáneas severas (RAM) como el Síndrome Stevens Johnson (SJS) y la Necrólisis Epidérmica Tóxica (NET),caracterizadas por exantema, erosión de la piel y las membranas mucosas, flictenas, desprendimiento de la piel secundario a la muerte de queratinocitos y compromiso ocular. Son infrecuentes en la población pero con elevada morbi-mortalidad, se presentan luego de la administración de diferentes fármacos. En Asia se ha asociado el alelo HLA-B*15:02 como m...

Mucosal complications of modified osteo-odonto keratoprosthesis in chronic Stevens-Johnson syndrome.

Science.gov (United States)

Basu, Sayan; Pillai, Vinay Sukumara; Sangwan, Virender S

2013-11-01

To describe clinical outcomes of complications afflicting the autologous oral mucous membrane graft after modified osteo-odonto keratoprosthesis surgery in chronic Stevens-Johnson syndrome (SJS). Prospective case series. This study included 30 eyes of 30 patients with SJS-induced dry keratinized ocular surfaces; the patients underwent various stages of this procedure between August 2009 and February 2012. Mucosal complications were classified as either necrosis or overgrowth. Mucosal necrosis was managed according to a predesigned algorithm based on timing (pre- and postimplantation) and location (central or peripheral) of necrosis. Cases with mucosal overgrowth underwent mucosal debulking and trimming. Mucosal necrosis developed in 15 (50%) eyes and overgrowth in 4 (13.3%) eyes. Preimplantation necrosis (n = 7) was initially managed conservatively, but 2 eyes required free labial-mucous membrane grafting for persistent corneal exposure. Free labial-mucous membrane grafting was performed in all cases of postimplantation necrosis (n = 10), but 8 eyes required additional tarsal pedicle flaps (n = 6, for peripheral necrosis) or through-the-lid revisions (n = 2, for central necrosis). Debulking and trimming effectively managed all cases of mucosal overgrowth, but 3 eyes required repeat procedures. At 24.1 ± 6.5 months postimplantation, the keratoprosthesis was retained in all eyes, and the probability of maintaining 20/60 or better vision was similar in eyes with or without mucosal necrosis (86 ± 8.8% vs 80 ± 10.3%). Mucosal complications, especially necrosis, occurred commonly following modified osteo-odonto keratoprosthesis surgery in dry keratinized post-SJS eyes. The algorithm-based management approach described in this study was successful in treating these complications, retaining the prosthesis and preserving useful vision. Copyright © 2013 Elsevier Inc. All rights reserved.

Sedimentology of a surficial uranium deposit on North Flodelle Creek, Stevens County, Washington

International Nuclear Information System (INIS)

Macke, D.L.; Johnson, S.Y.; Otton, J.K.

1985-01-01

Surficial accumulations of uranium (up to 0.2 wt. % U/sub 3/O/sub 8/, dry basis) are currently forming in organic-rich, poorly drained sediments deposited in fluvial-lacustrine environments. Known occurrences are in northeastern Washington, northern Idaho, the Sierra Nevada, the Colorado Front Range, New Hampshire, and several areas in Canada. The first accumulation of this type to be mined is in postglacial sediments of a 10-acre boggy meadow along North Flodelle Creek in Stevens County, Washington. The meadow is flanked by hills of fine- to medium-grained two-mica quartz monzonite that are mantled by glacial drift of late Wisconsin age (about 18,000 to 11,500 yr B.P.). Relatively thick, hummocky deposits of this same glacial drift impede drainage at the lower end of the meadow. Following ice retreat, glacial sediments on the meadow floor were reworked by fluvial processes, and patches of organic-rich sediment may have formed in ice-melt depressions. About 6700 yr B.P., a blanket of Mazama ash from the Crater Lake eruption was deposited in the meadow. Shortly thereafter, a beaver dam across the lower end of the meadow further restricted drainage, and peat and organic mud accumulated in the pond behind the dam. The dam is preserved in the stratigraphic record as a sheet-like body of woody peat (with beaver-gnawed sticks) about 100m wide and 60 cm thick. After the gradual influx of sand and coarse silt had filled the pond, and the beavers had abandoned the site, fluvial deposition was reestablished

A Tribute to Professor Steven L. Wechsler (1948-2016): The Man and the Scientist.

Science.gov (United States)

Nesburn, Anthony B; BenMohamed, Lbachir

2017-01-01

Professor Steven L. Wechsler, a world-renowned eye researcher and virologist, passed away unexpectedly on June 12, 2016 at the age of 68. Many scientists came to know Professor Wechsler as a gifted researcher in the field of ocular Herpes Simplex Virus (HSV-1) latency, reactivation, and pathogenesis. Professor Wechsler published over 150 peer-reviewed scientific papers during his career, pushing forward the frontiers of his field eye research. His colleagues would say, 'Steve literally wrote the book on herpes latency and reactivation.' He was the first to show that the HSV-1 latency-associated transcript (LAT) is essential for the HSV-1 high spontaneous reactivation phenotype and that LAT has anti-apoptosis activity. This discovery of LAT's anti-apoptosis activity, which is a key factor in how the LAT gene enhances reactivation, was published in Science in 2000 and created a new paradigm that greatly increased understanding of HSV-1 latency and reactivation. In collaboration with Professor Lbachir BenMohamed, an immunologist, they later demonstrated that LAT also acts as an immune evasion gene. He was a caring scientist who truly enjoyed working and sharing his experience and expertise with young researchers. He will be remembered as a significant pillar within scientific and ocular herpes research communities worldwide. Professor Wechsler's dedication to science, his compassionate character, and wonderful sense of humor were exemplary. We, who were his friends and colleagues, will mourn his passing deeply.

Topical Treatment for Stevens - Johnson Syndrome and Toxic Epidermal Necrolysis: A Review

Directory of Open Access Journals (Sweden)

Schandra Purnamawati

2016-08-01

Full Text Available Background: Stevens - Johnson syndrome (SJS and Toxic Epidermal Necrolysis (TEN are currently regarded to be same disease entity which differs only in the extent and severity of epidermal sloughing. Both are potentially life-threatening mucocutaneous immunologic reaction, which are most frequently induced by drug consumption. The epithelial destruction of skin and mucosal membrane can cause both acute as well as chronic/ long term outcomes in term of  late sequelae during the course of the disease. Sequelae often occur during the late phase of SJS/TEN and become a significant problem due its chronicity and severe degree of impairment, which leads to deterioration of quality of life for the patients. This may prevented or decreased in terms of intensity if the patient’s received prompt and sufficient topical therapy, particularly in managing lesions on the mucosa of the eye, oral, and genital. Objective : This review underlines topical therapies which could be delivered for management of mucocutaneous lesions from SJS/ TEN, aimed to prevent late sequelae due to SJS – TEN in order to improve the life quality of SJS – TEN survivors. Conclusion: SJS/ TEN frequently lead to late sequeale which includes skin, ocular, oral, and genital involvement. These sequelaes are often severe and chonic. Thus, may cause significant decrease in quality of life of SJS/TEN survivors. It is therefore most important to detect them early in order to manage them adequately. To date, we still have an impression that the specific sequelae of SJS – TEN are often late diagnosed and insufficiently treated. Finally, we want to emphasize that for mucosal involvement in particular, such as ocular, genital and oral involvement, a careful topical treatment have to be taken into special consideration in order to prevent severe late sequelae. 

The Pitfalls of Picturing Atlantic Slavery: Steven Spielberg’s Amistad vs Guy Deslauriers’s The Middle Passage

Directory of Open Access Journals (Sweden)

Lars Eckstein

2011-04-01

On the one hand, the arts are particularly called for in this situation to fill the documentary gaps and silences through acts of experiment and imagination, and they may indeed have a redemptive effect by offering, in Hayden White’s terms, successful ‘emplotments’ of a traumatic past. One the other hand, this redemptive potential simultaneously poses a serious ethical challenge: As Theodor W. Adorno has warned with reference to the Holocaust, it is precisely by making ‘sense’ of human suffering, and by making accessible to the ‘senses’ what is utterly senseless and incomprehensible, that injustice may be done to the victims. In this paper, I will try to illustrate this problematic by looking at two recent films that have attempted to represent the horrors of the middle passage – Steven Spielberg’s canonical Amistad (a terrible failure, in my view, and Guy Deslauriers’ film The Middle Passage [Passage du Milieu]. Based on a script by the Martiniquean novelist and poet Patrick Chamoiseau, the latter example uses an aesthetic approach which may point at a way out of the dilemma outlined above.

Qualidade de vida dos pacientes portadores de síndrome de Stevens-Johnson

Directory of Open Access Journals (Sweden)

Nogueira Ruth

2003-01-01

Full Text Available OBJETIVO: Avaliar a qualidade de vida dos pacientes portadores de síndrome de Stevens-Johnson. MÉTODOS: Foram avaliados 14 pacientes com SSJ no período de 1998 e 1999 no Setor de Córnea do Departamento de Oftalmologia da UNIFESP. Empregou-se o questionário S. F. 36 - pesquisa em saúde. A pontuação indica melhor condição de saúde. A mesma avaliação foi repetida quatro vezes em intervalo de três meses. RESULTADOS: As médias das médias das 4 avaliações dos 14 pacientes apresentaram importante redução dos seus valores em todos os subitens do S.F. 36 (41,04±22,38 para aspectos físicos, 53,82±22,82 para aspectos sociais, 26,24±22,46 para aspectos emocionais, 34,95±25,45 para capacidade funcional, 42,03±31,85 para dor, 46,33±18,37 para vitalidade, 46,18±24,83 para saúde mental e 50,26±16,29 para saúde geral. CONCLUSÃO: O questionário S.F. 36 representa método adequado de avaliação de aspectos físicos e emocionais em pacientes com baixa de acuidade visual, que nos permitiu detectar comprometimento importante nas funções básicas dos pacientes com SSJ. Mais pacientes com maior tempo de seguimento são necessários para aprimorar a análise de qualidade de vida nesses pacientes e avaliar os efeitos do acompanhamento psicológico.

Higher-order Zeeman and spin terms in the electron paramagnetic resonance spin Hamiltonian; their description in irreducible form using Cartesian, tesseral spherical tensor and Stevens' operator expressions

International Nuclear Information System (INIS)

McGavin, Dennis G; Tennant, W Craighead

2009-01-01

In setting up a spin Hamiltonian (SH) to study high-spin Zeeman and high-spin nuclear and/or electronic interactions in electron paramagnetic resonance (EPR) experiments, it is argued that a maximally reduced SH (MRSH) framed in tesseral combinations of spherical tensor operators is necessary. Then, the SH contains only those terms that are necessary and sufficient to describe the particular spin system. The paper proceeds then to obtain interrelationships between the parameters of the MRSH and those of alternative SHs expressed in Cartesian tensor and Stevens operator-equivalent forms. The examples taken, initially, are those of Cartesian and Stevens' expressions for high-spin Zeeman terms of dimension BS 3 and BS 5 . Starting from the well-known decomposition of the general Cartesian tensor of second rank to three irreducible tensors of ranks 0, 1 and 2, the decomposition of Cartesian tensors of ranks 4 and 6 are treated similarly. Next, following a generalization of the tesseral spherical tensor equations, the interrelationships amongst the parameters of the three kinds of expressions, as derived from equivalent SHs, are determined and detailed tables, including all redundancy equations, set out. In each of these cases the lowest symmetry, 1-bar Laue class, is assumed and then examples of relationships for specific higher symmetries derived therefrom. The validity of a spin Hamiltonian containing mixtures of terms from the three expressions is considered in some detail for several specific symmetries, including again the lowest symmetry. Finally, we address the application of some of the relationships derived here to seldom-observed low-symmetry effects in EPR spectra, when high-spin electronic and nuclear interactions are present.

Fatal Toxic Epidermal Necrolysis Induced by Carbamazepine Treatment in a Patient Who Previously had Carbamazepine-induced Stevens-Johnson Syndrome

Directory of Open Access Journals (Sweden)

Li-Yen Huang

2007-12-01

Full Text Available Toxic epidermal necrolysis (TEN is a rare but life-threatening skin disease that is most commonly drug-induced. It has recently been suggested that Stevens-Johnson syndrome (SJS belongs to the same group of skin disorders, although it has a lower mortality rate than TEN. We report the case of a 26-year-old male schizophrenic patient with a history of carbamazepine-induced SJS 5 years earlier. At the time of his current admission, he was admitted to our psychiatry department with acute agitation due to schizophrenia. However, the patient and his family denied history of drug allergy. After 3 days of carbamazepine treatment, the patient developed TEN (body surface area > 90%. He was transferred to the burn center, but despite appropriate treatment, including intravenous hydrocortisone 200 mg q6h and being covered with sterile biological material, he died. It is important to note that re-administration of a drug that previously caused SJS may lead to TEN, which has a very high mortality rate.

Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN): could retinoids play a causative role?

Science.gov (United States)

Mawson, Anthony R; Eriator, Ike; Karre, Sridhar

2015-01-12

Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are overlapping manifestations on a spectrum of acute drug-induced conditions associated with severe blistering, skin peeling, and multi-organ damage. TEN is an eruption resembling severe scalding, with ≥30% skin detachment. SJS is a mild form of TEN, characterized histologically by epidermal keratinocyte apoptosis with dermo-epidermal separation and extensive small blisters with <10% body surface skin detachment. The syndrome can be induced by numerous medications and typically occurs 1-4 weeks after the initiation of therapy. Granulysin is found in the lesions of patients with SJS/TEN and plays a significant pathogenic role in the condition, but the overall mechanisms linking medications, granulysin, and disease manifestations remain obscure. This paper reviews evidence suggesting that the different medications implicated in SJS/TEN have the common property of interacting and synergizing with endogenous retinoids (vitamin A and its congeners), in many instances causing the latter to accumulate in and damage the liver, the main storage organ for vitamin A. It is hypothesized that liver damage leads to the spillage of toxic retinoid compounds into the circulation, resulting in an endogenous form of hypervitaminosis A and cytotoxicity with widespread apoptosis, mediated by granulysin and recognized as SJS/TEN. Subject to testing, the model suggests that symptom worsening could be arrested at onset by lowering the concentration of circulating retinoids and/or granulysin via phlebotomy or plasmapheresis or by pharmacological measures to limit their expression.

Data Mining FAERS to Analyze Molecular Targets of Drugs Highly Associated with Stevens-Johnson Syndrome.

Science.gov (United States)

Burkhart, Keith K; Abernethy, Darrell; Jackson, David

2015-06-01

Drug features that are associated with Stevens-Johnson syndrome (SJS) have not been fully characterized. A molecular target analysis of the drugs associated with SJS in the FDA Adverse Event Reporting System (FAERS) may contribute to mechanistic insights into SJS pathophysiology. The publicly available version of FAERS was analyzed to identify disproportionality among the molecular targets, metabolizing enzymes, and transporters for drugs associated with SJS. The FAERS in-house version was also analyzed for an internal comparison of the drugs most highly associated with SJS. Cyclooxygenases 1 and 2, carbonic anhydrase 2, and sodium channel 2 alpha were identified as disproportionately associated with SJS. Cytochrome P450 (CYPs) 3A4 and 2C9 are disproportionately represented as metabolizing enzymes of the drugs associated with SJS adverse event reports. Multidrug resistance protein 1 (MRP-1), organic anion transporter 1 (OAT1), and PEPT2 were also identified and are highly associated with the transport of these drugs. A detailed review of the molecular targets identifies important roles for these targets in immune response. The association with CYP metabolizing enzymes suggests that reactive metabolites and oxidative stress may have a contributory role. Drug transporters may enhance intracellular tissue concentrations and also have vital physiologic roles that impact keratinocyte proliferation and survival. Data mining FAERS may be used to hypothesize mechanisms for adverse drug events by identifying molecular targets that are highly associated with drug-induced adverse events. The information gained may contribute to systems biology disease models.

Síndrome de Stevens Johnson, presentación de un caso en edad pediátrica

Directory of Open Access Journals (Sweden)

Maritza Morales Solís

2015-11-01

Full Text Available El síndrome de Stevens-Johnson (SSJ es una variante severa del eritema multiforme, consistente en una reacción de hipersensibilización que afecta piel y mucosa, además de otros órganos internos, y que se manifiesta con lesiones en zonas genitales, bucales y cutáneas, es idiopático en el 50% de los casos, generalmente producido por alergia a medicamentos. La muerte sobreviene en el 5-15% de los casos sin tratar. El riesgo de recurrencia es del 37% o más.  Al Hospital Pediátrico Provincial Docente “Mártires de Las Tunas”  fue  traído un niño de seis años  de edad, que tras el uso del Sulfaprín comenzó con lesiones que afectaban la piel y  todas las mucosas, además de toma del estado general. Inmediatamente fue admitido en la Unidad de Cuidados  Intensivos Pediátricos, donde fueron tomadas medidas que incluyeron supresión del agente causal,  corticoterapia endovenosa, antibioticoterapia endovenosa, tratamiento de las lesiones, vigilancia del balance hidromineral y atención oftalmológica, respondiendo favorablemente. Se presenta el caso, por ser una enfermedad poco frecuente y de muy mal pronóstico.

Síndrome de Stevens-Johnson e Necrólise Epidérmica Tóxica em um hospital do Distrito Federal

Directory of Open Access Journals (Sweden)

Mariane Ferreira Barbosa Emerick

2014-12-01

Full Text Available Objetivou-se analisar as características demográficas e clínicas dos clientes diagnosticados com Síndrome de Stevens Johnson (SSJ e Necrólise Epidérmica Tóxica (NET, bem como identificar as ações dos profissionais de saúde para o manejo das Reações Adversas a Medicamentos (RAM em um hospital público do Distrito Federal. Pesquisa descritiva, retrospectiva, com abordagem quantitativa. Dados coletados em todos os prontuários de 22 clientes internados de janeiro de 2005 a setembro de 2012. Análise mediante estatística descritiva. Houve aumento gradativo de casos, com maior número nos anos de 2007 e 2012. Dos casos analisados, 9 foram diagnosticados com NET e 7 com SSJ; predominaram as mulheres (14 e a faixa etária de 21 aos 40 anos (10; 21 obtiveram cura. Os fármacos associados a RAM mais frequentes foram os antiepilépticos (10. Observou-se fragilidade nos registros clínicos nos prontuários e nas ações de monitoramento de RAM no serviço estudado.

Nine years of a single referral center management of Stevens-Johnson syndrome and toxic epidermal necrolysis (Lyell's syndrome).

Science.gov (United States)

Monteiro, Diana; Egipto, Paula; Barbosa, Julia; Horta, Ricardo; Amarante, Jose; Silva, Pedro; Silva, Alvaro

2017-06-01

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) corresponds to a rare and acute life-threatening mucocutaneous reactions characterized by extensive necrosis and epidermal detachment. There are no efficacious pharmaceutical interventions proven through large clinical trials. We sought to study clinical cases admitted in our institution in order to determine which drugs and medical comorbidities or treatments impacted the mortality. In a retrospective study over 9 years we evaluated all patients presenting biopsy-proven SJS or TEN for age, gender, total body surface area involved, causing agents, SCORTEN score, blood transfusion, steroid administration, intubation, length of intensive care stay and death rate. Statistical analysis was done using SPSS statistical software. The highest incidence of SJS and TEN was in age group of 71-80 years. Of the 30 patients, 30% died from SJS/TEN, mainly due sepsis. For each subgroup SJS/TEN overlap had the highest mortality. The highest mortality was from antibiotic treatment as causing agent. Step-wise regression analysis identified mechanical ventilation requirement and age over 65 years as mortality high-risk factors. The most crucial interventions are discontinuation of the offending drug and prompt referral to a burn unit, which helps in early diagnosis and decrease mortality in these diseases. When SJS/TEN is caused by antibiotics suspicion of developing fatal sepsis should be high, independently of patients' medical condition.

Enrico Fermi Awards Ceremony for Dr. Mildred S. Dresselhaus and Dr. Burton Richter, May 2012 (Presentations, including remarks by Energy Secretary, Dr. Steven Chu)

International Nuclear Information System (INIS)

Chu, Steven

2012-01-01

The Fermi Award is a Presidential award and is one of the oldest and most prestigious science and technology honors bestowed by the U.S. Government. On May 7, 2012 it was conferred upon two exceptional scientists: Dr. Mildred Dresselhaus, 'for her scientific leadership, her major contributions to science and energy policy, her selfless work in science education and the advancement of diversity in the scientific workplace, and her highly original and impactful research,' and Dr. Burton Richter, 'for the breadth of his influence in the multiple disciplines of accelerator physics and particle physics, his profound scientific discoveries, his visionary leadership as SLAC Director, his leadership of science, and his notable contributions in energy and public policy.' Dr. John Holder, Director of the White House Office of Science and Technology Policy, opened the ceremony, and Dr. Bill Brinkman, Director of DOE's Office of Science introduced the main speaker, Dr. Steven Chu, U.S. Energy Secretary.

Improving mortality outcomes of Stevens Johnson syndrome/toxic epidermal necrolysis: A regional burns centre experience.

Science.gov (United States)

Nizamoglu, M; Ward, J A; Frew, Q; Gerrish, H; Martin, N; Shaw, A; Barnes, D; Shelly, O; Philp, B; El-Muttardi, N; Dziewulski, P

2018-05-01

Stevens Johnson Syndrome/toxic epidermal necrolysis (SJS/TEN) are rare, potentially fatal desquamative disorders characterised by large areas of partial thickness skin and mucosal loss. The degree of epidermal detachment that occurs has led to SJS/TEN being described as a burn-like condition. These patients benefit from judicious critical care, early debridement and meticulous wound care. This is best undertaken within a multidisciplinary setting led by clinicians experienced in the management of massive skin loss and its sequelae. In this study, we examined the clinical outcomes of SJS/TEN overlap & TEN patients managed by our regional burns service over a 12-year period. We present our treatment model for other burn centres treating SJS/TEN patients. A retrospective case review was performed for all patients with a clinical diagnosis of TEN or SJS/TEN overlap admitted to our paediatric and adult burns centre between June 2004 and December 2016. Patient demographics, percentage total body surface area (%TBSA), mucosal involvement, causation, severity of illness score (SCORTEN), length of stay and survival were appraised with appropriate statistical analysis performed using Graph Pad Prism 7.02 Software. During the study period, 42 patients (M26; F: 16) with TEN (n=32) and SJS/TEN overlap (n=10) were managed within our burns service. Mean %TBSA of cutaneous involvement was 57% (range 10-100%) and mean length of stay (LOS) was 27 days (range 1-144 days). We observed 4 deaths in our series compared to 16 predicted by SCORTEN giving a standardised mortality ratio (SMR) of 24%. Management in our burns service with an aggressive wound care protocol involving debridement of blistered epidermis and wound closure with synthetic and biological dressings seems to have produced benefits in mortality when compared to predicted outcomes. Copyright © 2017 Elsevier Ltd and ISBI. All rights reserved.

Response to Dr Stevens' letter ref. Visitisen et al: "Short-term effects of night shift work on breast cancer risk: a cohort study of payroll data"

DEFF Research Database (Denmark)

Kolstad, Henrik A; Garde, Anne Helene; Hansen, Åse Marie

2017-01-01

We thank Dr Richard Stevens for his comments (1) on our recent article that showed no increased risk of breast cancer following recent night shift work when compared with recent day shift work (2). This finding was based on linkage of day-by-day information on working hours and breast cancer...... incidence data. Results are thus less likely to have been biased by differential misclassification than findings from earlier studies relying on self-report (3). We defined a night shift as ≥3 hours of work between 24:00-05:00 hours and a day shift as ≥3 hours work between 6:00-20:00 hours. This day shift...... definitions of shifts affect the risk of breast cancer, which will be possible using this type of data. We only had information on working hours from 2007 and onwards, and night shift work prior to 2007 could have confounded our analyses towards no effect but only if inversely associated with night shift work...

Stevens-Johnson syndrome and toxic epidermal necrolysis in childhood-onset systemic lupus erythematosus patients: a multicenter study

Directory of Open Access Journals (Sweden)

Ana Paula Sakamoto

2017-07-01

Full Text Available Objective: To assess Stevens-Johnson syndrome (SJS and toxic epidermal necrolysis (TEN in a large population of childhood-onset systemic lupus erythematosus (cSLE patients. Methods: Multicenter study including 852 cSLE patients followed in Pediatric Rheumatology centers in São Paulo, Brazil. SJS was defined as epidermal detachment below 10% of body surface area (BSA, overlap SJS-TEN 10-30% and TEN greater than 30% of BSA. Results: SJS and TEN was observed in 5/852 (0.6% cSLE female patients, three patients were classified as SJS and two patients were classified as overlap SJS-TEN; TEN was not observed. The mean duration of SJS and overlap SJS-TEN was 15 days (range 7-22 and antibiotics induced four cases. Regarding extra-cutaneous manifestations, hepatomegaly was observed in two cSLE patients, nephritis in two and neuropsychiatric involvement and conjunctivitis were observed respectively in one patient. Hematological involvement included lymphopenia in four, leucopenia in three and thrombocytopenia in two patients. The mean SLEDAI-2K score was 14.8 (range 6-30. Laboratory analysis showed low C3, C4 and/or CH50 in two patients and the presence of anti-dsDNA autoantibody in two patients. One patient had lupus anticoagulant and another one had anticardiolipin IgG. All patients were treated with steroids and four needed additional treatment such as intravenous immunoglobulin in two patients, hydroxychloroquine and azathioprine in two and intravenous cyclophosphamide in one patient. Sepsis was observed in three cSLE patients. Two patients required intensive care and death was observed in one patient. Conclusion: Our study identified SJS and overlap SJS-TEN as rare manifestations of active cSLE associated with severe multisystemic disease, with potentially lethal outcome.

In Silico Risk Assessment of HLA-A*02:06-Associated Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Caused by Cold Medicine Ingredients

Directory of Open Access Journals (Sweden)

Hideto Isogai

2013-01-01

Full Text Available Stevens-Johnson syndrome (SJS and toxic epidermal necrolysis (TEN are severe drug hypersensitivities with high mortality. Typical over-the-counter drugs of cold medicines are suggested to be causative. As multiple ingredients are generally contained in cold medicines, it is of particular interest to investigate which ingredients are responsible for SJS/TEN. However, experimental examination of causal relationships between SJS/TEN and a particular drug molecule is not straightforward. Significant association between HLA-A*02:06 and SJS/TEN with severe ocular surface complications has been observed in the Japanese. In the present study, we have undertaken in silico docking simulations between various ingredients contained in cold medicines available in Japan and the HLA-A*02:06 molecule. We use the composite risk index (CRI that is the absolute value of the binding affinity multiplied by the daily dose to assess the potential risk of the adverse reactions. The drugs which have been recognized as causative drugs of SJS/TEN in Japan have revealed relatively high CRI, and the association between SJS/TEN and HLA-A*02:06 has been qualitatively verified. The results have also shown that some drugs whose links to SJS/TEN have not been clinically recognized in Japan show the high CRI and suggested that attention should be paid to their adverse drug reactions.

Inter population variability of frost-resistance in provenances of scot pines (Pinusylvestris L.R. hamata Steven in Turkey

Directory of Open Access Journals (Sweden)

Özel Halil Barış

2016-01-01

Full Text Available Frost-resistance variability of Scotch pine (Pinus sylvestris L. var. hamata Steven seedlings grown in nurseries conditions, originated from 10 provenances, have been analyzed. The provenances from Black Sea region, Central Anatolian region and Eastern Anatolian region in Turkey have been used in selection of seed zones. The results of frost-resistance tests indicated a strong relationship of implemented freezing degrees with injury degrees of Scotch pine needles and photosynthetic productivities. On the other hand, another significant relationship has been determined between chlorophyll fluorescence and ion leakage methods (r=-0.801. This result shows that those two methods can be safely used in determining the damages due to low temperatures. In frost resistance tests, Scotch pine seedlings from different provenances have been frozen at -10, -20, -30 and -40°C. According to the Duncan test results, it has been determined that damage increased as temperature decreased. The damage level at -10°C implementation is 3.5% which can be tolerated by plants. But when the temperature has been decreased to -20°C, the level of damage has increased to 51.25%. As a result of photosynthetic analyses in this phase, it has been determined that there is a statistically significant relationship between provenances and temperature levels. Under the light of those findings, they have determined that the photosynthetic productivity has significantly decreased at temperatures between -20°C and -40°C. This situation conforms to injury index values determined in this study. As a result of injury index and photosynthetic productivity tests used for determining the damage after frost-resistance tests, it has been determined that the provenances of Amasya-Kunduz, Bolu-Aladağ, Düzce-Yığılca, Samsun-Vezirköprü and Eskişehir-Çatacık are more sensitive to frost than other provenances.

Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Standard Reporting and Evaluation Guidelines: Results of a National Institutes of Health Working Group.

Science.gov (United States)

Maverakis, Emanual; Wang, Elizabeth A; Shinkai, Kanade; Mahasirimongkol, Surakameth; Margolis, David J; Avigan, Mark; Chung, Wen-Hung; Goldman, Jennifer; La Grenade, Lois; Pirmohamed, Munir; Shear, Neil H; Tassaeeyakul, Wichittra; Hoetzenecker, Wolfram; Klaewsongkram, Jettanong; Rerkpattanapipat, Ticha; Manuyakorn, Wiparat; Yasuda, Sally Usdin; Sharon, Victoria R; Sukhov, Andrea; Micheletti, Robert; Struewing, Jeff; French, Lars E; Cheng, Michelle Y

2017-06-01

Toxic epidermal necrolysis (TEN) and Stevens-Johnson Syndrome (SJS) are rare, acute, life-threatening dermatologic disorders involving the skin and mucous membranes. Research into these conditions is hampered by a lack of standardization of case reporting and data collection. To establish a standardized case report form to facilitate comparisons and maintain data quality based on an international panel of SJS/TEN experts who performed a Delphi consensus-building exercise. The elements presented for committee scrutiny were adapted from previous case report forms and from PubMed literature searches of highly cited manuscripts pertaining to SJS/TEN. The expert opinions and experience of the members of the consensus group were included in the discussion. Overall, 21 out of 29 experts who were invited to participate in the online Delphi exercise agreed to participate. Surveys at each stage were administered via an online survery software tool. For the first 2 Delphi rounds, results were analyzed using the Interpercentile Range Adjusted for Symmetry method and statements that passed consensus formulated a new case report form. For the third Delphi round, the case report form was presented to the committee, who agreed that it was "appropriate and useful" for documenting cases of SJS/TEN, making it more reliable and valuable for future research endeavors. With the consensus of international experts, a case report form for SJS/TEN has been created to help standardize the collection of patient information in future studies and the documentation of individual cases.

Neutrophil Collagenase, Gelatinase and Myeloperoxidase in Tears of Stevens-Johnson Syndrome and Ocular Cicatricial Pemphigoid Patients

Science.gov (United States)

Arafat, Samer N.; Suelves, Ana M.; Spurr-Michaud, Sandra; Chodosh, James; Foster, C. Stephen; Dohlman, Claes H.; Gipson, Ilene K.

2013-01-01

Objective To investigate the levels of matrix metalloproteinases (MMPs), myeloperoxidase (MPO) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in tears of patients with Stevens-Johnson syndrome (SJS) and ocular cicatricial pemphigoid (OCP). Design Prospective non-interventional cohort study. Participants Four SJS patients (7 eyes), 19 OCP patients (37 eyes) and 20 post-phacoemulsification healthy controls (40 eyes). Methods Tear washes were collected from all patients and were analyzed for levels of MMP-2, -3, -7, -8, -9, -12, MPO and TIMP-1 using multi-analyte bead-based enzyme-linked immunosorbent assays (ELISA). Total MMP activity was determined using a fluorimetric assay. Correlation studies were performed between the various analytes within study groups. Main Outcome Measures Levels of MMP-2, -3, -7, -8, -9, -12, MPO and TIMP-1 (in ng/µg protein), total MMP activity (in relative fluorescent units/min/µg protein) in tears, MMP-8/TIMP-1, MMP-9/TIMP-1 ratios and the correlations between MMP-8 and MMP-9 and each MMP and MPO. Results MMP-8, MMP-9 and MPO levels were significantly elevated in SJS and OCP tears (SJS > OCP) when compared to controls. MMP activity was highest in SJS while OCP and controls showed lower and similar activities. TIMP-1 levels were decreased in SJS and OCP when compared to controls with OCP levels reaching significance. MMP-8/TIMP-1 and MMP-9/TIMP-1 ratios were markedly elevated in SJS and OCP tears (SJS > OCP) when compared to controls. Across all study groups, MMP-9 levels correlated strongly with MMP-8 and MPO levels and MMP-8 correlated with MPO but did not reach significance in SJS. There was no relationship between MMP-7 and MPO. Conclusions Since MMP-8 and MPO are produced by inflammatory cells, particularly neutrophils, the correlation data indicate that they may be the common source of elevated enzymes including MMP-9 in SJS and OCP tears. Elevated MMP/TIMP ratios and MMP activity suggest an imbalance in tear MMP regulation

Survey of Nonprescription Medication and Antibiotic Use in Patients with Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis, and Overlap Syndrome

Directory of Open Access Journals (Sweden)

Katherine J. Sullivan

2018-02-01

Full Text Available Stevens-Johnson syndrome (SJS, toxic epidermal necrolysis (TEN, and overlap syndrome (SJS-TEN are rare, serious skin and mucosa break-down conditions frequently associated with antibiotic use. The role of nonprescription medications alone, or in combination with antibiotics in triggering SJS/TEN, is largely unknown. This study summarized data collected from patient surveys about nonprescription and antibiotic use prior to a SJS/TEN diagnosis. The survey was administered online to members of the U.S. SJS Foundation who had been diagnosed with SJS/TEN or were the parent of a child who had been diagnosed with SJS/TEN. Respondents were asked about nonprescription medications taken within the year before diagnosis, and the approximate point in time before diagnosis that they had taken them. They were also asked about specific prescription medications, including antibiotics, that they took before diagnosis. An estimated 4500 patients received an invitation to complete the survey. 251 patients completed it, resulting in a response rate of 5.6%. The mean age of respondents was 43 years (SD (standard deviation = 17.3 and 70% were female. 32.3% of respondents indicated that a prescription antibiotic triggered their reaction. 14.1% indicated a nonprescription medication had triggered their SJS/TEN, and 18.1% said a nonprescription medication may have triggered their SJS/TEN. 85.5% of respondents said they took a nonprescription medication within three months of their SJS/TEN diagnosis. Of those respondents who reported that an antibiotic triggered their SJS/TEN, 35.2% reported taking a nonprescription medication within the three months prior to their diagnosis. This survey captured valuable information about nonprescription and antibiotic use in SJS/TEN patients. It is important for future studies to estimate the impact of antibiotics on SJS/TEN, and account for nonprescription medication use in that relationship.

78 FR 8547 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2013-02-06

... Prickett (NHGRI), and Steven Rosenberg (NCI). Publication: Prickett TD, et al. Exon capture analysis of G... Steven Rosenberg (NCI) Publication: Prickett TD, et al. Exon capture analysis of G-protein coupled... Steven Rosenberg (NCI) Publication: Cronin JC, et al. Frequent mutations in the MITF pathway in melanoma...

CYP2C19*2 status in patients with Stevens-Johnson syndrome and toxic epidermal necrolysis

Directory of Open Access Journals (Sweden)

Laska AJ

2017-05-01

Full Text Available Amanda J Laska,1 Marie J Han,1 Josh A Lospinoso,2 Patrick J Brown,1 Thomas M Beachkofsky1 1Department of Dermatology, San Antonio Uniformed Services Health Education Consortium, San Antonio, TX, 2780th Military Intelligence Brigade, Ft Meade, MD, USA Purpose: Genetic polymorphisms have been linked to an increased predisposition to developing certain diseases. For example, patients of Han-Chinese descent carrying the HLA-B*1502 allele are at an increased risk of developing Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN if given carbamazepine. Given the complexity of in vivo drug metabolism, it is plausible that the activity of enzyme systems unrelated to specific drug metabolism may be important. Although multiple biomarkers have been identified in unique ethnic groups, there has yet to be a study investigating the presence of the slow metabolizing allele of CYP2C19, denoted CYP2C19*2, in diverse groups and the risk of developing SJS/TEN. Patients and methods: This study looked into the carrier status of CYP2C19*2, a poor metabolizing variant of CYP2C19, in patients diagnosed with SJS/TEN. We looked at its status in our series as a whole and when patients were divided by ethnicity. Genomic DNA was extracted from formalin-fixed paraffin-embedded tissue of patients with biopsy-proven SJS/TEN and real-time polymerase chain reaction was used to assess for the presence of CYP2C19*2. Results: CYP2C19*2 status was determined in 47 patients. Twenty-nine of these 47 patients had a single medication implicated as causing their disease, and eight of these patients were heterozygous or homozygous for CYP2C19*2. There was insufficient evidence to conclude that the presence of CYP2C19*2 is an independent predictor of risk for developing SJS/TEN in our series as a whole. This analysis also confirmed that the frequency of the CYP2C19*2 polymorphism within the different ethnicities in our series did not vary statistically from reported ethnic

Clinical Features and Treatment Outcomes among Children with Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A 20-Year Study in a Tertiary Referral Hospital

Directory of Open Access Journals (Sweden)

Susheera Chatproedprai

2018-01-01

Full Text Available Aim. To determine the probable causative factors, clinical features, and treatment outcomes of Stevens-Johnson syndrome (SJS, toxic epidermal necrolysis (TEN, and SJS-TEN overlap in children. Methods. A 20-year database review of all children diagnosed with SJS/TEN/SJS-TEN overlap at the King Chulalongkorn Memorial Hospital, Thailand. Results. 36 patients (M : F, 16 : 20 with the mean age of 9.2±4.0 years were identified. There were 20 cases of SJS, 4 cases of SJS-TEN overlap, and 12 cases of TEN. Drugs were the leading cause for the diseases (72.3%; antiepileptics were the most common culprits (36.1%. Cutaneous morphology at presentation was morbilliform rash (83.3%, blister (38.9%, targetoid lesions (25.0%, and purpuric macules (2.8%. Oral mucosa (97.2% and eye (83.3% were the 2 most common mucosal involvements. Majority of the cases (77.8% were treated with systemic corticosteroids, intravenous immunoglobulin, or both. Treatment outcomes between those who received systemic therapy and those who received only supportive care were comparable. Skin and eye were the principal sites of short-term and long-term complications. Conclusions. SJS/TEN are not common but are serious diseases which lead to significant morbidities in children. Early withdrawal of suspicious causes and meticulous supportive care are very important. This study found that the systemic therapy was not superior to supportive care because the treatment outcomes for both groups were comparable.

Stevens Johnson Syndrome and Toxic Epidermal Necrolysis: Maternal and Foetal Outcomes in Twenty-Two Consecutive Pregnant HIV Infected Women.

Directory of Open Access Journals (Sweden)

Lauren Knight

Full Text Available Stevens-Johnson syndrome (SJS and toxic epidermal necrolysis (TEN form a spectrum of a rare and life-threatening cutaneous drug reaction. SJS/TEN in pregnancy poses largely unknown risk factors and outcomes for both the mother and foetus compared to the general population.We conducted a study of consecutive pregnant women admitted to single tertiary referral centre in South Africa with SJS/TEN over a 3 year period. They were all managed by the same medical team using the same protocols. We evaluated their underlying illnesses, offending drugs and the course of pregnancy and outcomes to determine factors influencing maternal and foetal outcomes.We identified twenty-two women who developed SJS/TEN while pregnant, all of them HIV-infected. Their median age was 29 years. The majority 16/22 (73% had SJS, the milder variant of the disease affecting < 10% body surface area. Nevirapine was the offending drug in 21/22 (95% cases. All 22 of the mothers survived with 3/22 (14% developing postpartum sepsis. Pregnancy outcomes were known in 18/22 women and 9/18 (50% babies were delivered by caesarean section. There were 2 foetal deaths at 21 and 31 weeks respectively and both were associated with post-partum sepsis. Postnatal complications occurred in 5 cases, 3 involving the respiratory system and the other two being low birth weight deliveries. Eight placentae and one foetus were sent for histology and none showed macroscopic or microscopic features of SJS/TEN. On follow-up, only 12/20 children were tested for HIV at 6 weeks post-delivery and none of them were HIV-infected. All had received prophylactic ARVs including nevirapine.TEN, the severe form of the disease, was associated with poorer foetal outcomes. SJS/TEN-associated mortality is not increased in HIV-infected pregnant women. Maternal SJS/TEN does not seem to commonly manifest in the foetus.

77 FR 40073 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2012-07-06

... Immunotherapy. For collaboration opportunities, please contact Steven A. Rosenberg, M.D., Ph.D. at [email protected], Richard A. Morgan, Steven A. Rosenberg (all of NCI). Intellectual Property: HHS Reference No. E-105-2012/0... contact Steven A. Rosenberg, M.D., Ph.D. at [email protected] . Antagonists of Hyaluronan Signaling for...

Mission Engineering Competencies Technical Report

Science.gov (United States)

2018-04-30

technology has changed history , Apollo lunar program made a staggering contribution to high tech development. Report No. SERC-2018-TR-106...Gregg Vesonder, Stevens Institute of Technology Co-Principal Investigator: Dr. Dinesh Verma, Stevens Institute of Technology Research Team...Stevens Institute of Technology : Dr. Nicole Hutchison, Mr. Sergio Luna, Mr. William Miller, Dr. Hoong Yan See Tao, Dr. Jon

Neutrophil collagenase, gelatinase, and myeloperoxidase in tears of patients with stevens-johnson syndrome and ocular cicatricial pemphigoid.

Science.gov (United States)

Arafat, Samer N; Suelves, Ana M; Spurr-Michaud, Sandra; Chodosh, James; Foster, C Stephen; Dohlman, Claes H; Gipson, Ilene K

2014-01-01

To investigate the levels of matrix metalloproteinases (MMPs), myeloperoxidase (MPO), and tissue inhibitor of metalloproteinase-1 (TIMP-1) in tears of patients with Stevens-Johnson syndrome (SJS) and ocular cicatricial pemphigoid (OCP). Prospective, noninterventional cohort study. Four SJS patients (7 eyes), 19 OCP patients (37 eyes), and 20 healthy controls who underwent phacoemulsification (40 eyes). Tear washes were collected from all patients and were analyzed for levels of MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-12, MPO, and TIMP-1 using multianalyte bead-based enzyme-linked immunosorbent assays. Total MMP activity was determined using a fluorometric assay. Correlation studies were performed between the various analytes within study groups. Levels of MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-12, MPO, and TIMP-1 (in nanograms per microgram of protein) and total MMP activity (in relative fluorescent units per minute per microgram of protein) in tears; MMP-8-to-TIMP-1 ratio; MMP-9-to-TIMP-1 ratio; and the correlations between MMP-8 and MMP-9 and both MMP and MPO. MMP-8, MMP-9, and MPO levels were elevated significantly in SJS and OCP tears (SJS>OCP) when compared with controls. The MMP activity was highest in SJS patients, whereas OCP patients and controls showed lower and similar activities. The TIMP-1 levels were decreased in SJS and OCP patients when compared with those in controls, with levels in OCP patients reaching significance. The MMP-8-to-TIMP-1 and MMP-9-to-TIMP-1 ratios were markedly elevated in SJS and OCP tears (SJS>OCP) when compared with those of controls. Across all study groups, MMP-9 levels correlated strongly with MMP-8 and MPO levels, and MMP-8 correlated with MPO, but it did not reach significance in SJS patients. There was no relationship between MMP-7 and MPO. Because MMP-8 and MPO are produced by inflammatory cells, particularly neutrophils, the correlation data indicate that they may be the common source of elevated enzymes, including MMP-9

Purupaljaks / Steven Bertoni

Index Scriptorium Estoniae

Bertoni, Steven

2013-01-01

Duty Free Shoppersi asutaja Chuck Feeney on oma sihtasutusega Atlantic Philanthropies 30 aasta jooksul annetanud juba üle 6 miljardi dollari toetades erinevaid meditsiini, haridust ning päästeprojekte kogu maailmas, tehes seejuures kõik, et tema isik avalikuks ei tuleks

Response to Dr Stevens' letter ref. Visitisen et al: "Short-term effects of night shift work on breast cancer risk: a cohort study of payroll data".

Science.gov (United States)

Kolstad, Henrik A; Garde, Anne Helene; Hansen, Åse Marie; Frydenberg, Morten; Christiansen, Peer; Vistisen, Helene Tilma; Bonde, Jens Peter E

2017-01-01

We thank Dr Richard Stevens for his comments (1) on our recent article that showed no increased risk of breast cancer following recent night shift work when compared with recent day shift work (2). This finding was based on linkage of day-by-day information on working hours and breast cancer incidence data. Results are thus less likely to have been biased by differential misclassification than findings from earlier studies relying on self-report (3). We defined a night shift as ≥3 hours of work between 24:00-05:00 hours and a day shift as ≥3 hours work between 6:00-20:00 hours. This day shift definition did not exclude shifts starting before 05:00 or ending after 24:00 hours. However, this affected only 0.02% and 0.3% of all day shifts, respectively. This diminutive misclassification, that is expected to be non-differential, can hardly explain our negative findings. It is suggested that shifts that begin after 07:00 and end before 18:00 would constitute a more sensible baseline comparison group. Since the biological mechanism is not certain, it is not obvious to us if this will be a more appropriate reference than the present. However, we agree that future studies should test how different definitions of shifts affect the risk of breast cancer, which will be possible using this type of data. We only had information on working hours from 2007 and onwards, and night shift work prior to 2007 could have confounded our analyses towards no effect but only if inversely associated with night shift work in 2007 or later. We find this unlikely. Left truncation could also have biased findings towards the null. We therefore supplemented analyses of the total study population with analyses of the one-third of the population with first recorded employment in 2008 or later (the inception population). Even if the mean age was 35.5 years - and many undoubtedly had been working (with and without night shifts) prior to 2008 - this population should be less affected by such

Minor salivary glands and labial mucous membrane graft in the treatment of severe symblepharon and dry eye in patients with Stevens-Johnson syndrome.

Science.gov (United States)

Sant' Anna, Ana Estela B P P; Hazarbassanov, Rossen M; de Freitas, Denise; Gomes, José Álvaro P

2012-02-01

To evaluate minor salivary glands and labial mucous membrane graft in patients with severe symblepharon and dry eye secondary to Stevens-Johnson syndrome (SJS). A prospective, non-comparative, interventional case series of 19 patients with severe symblepharon and dry eye secondary to SJS who underwent labial mucous membrane and minor salivary glands transplantation. A complete ophthalmic examination including the Schirmer I test was performed prior to and following surgery. All patients had a preoperative Schirmer I test value of zero. Nineteen patients with severe symblepharon and dry eye secondary to SJS were included in the study. There was a statistically significant improvement in the best spectacle-corrected visual acuity in eight patients (t test; p=0.0070). Values obtained in the Schirmer I test improved significantly in 14 eyes (73.7%) 6 months following surgery (χ(2) test; p=0.0094). A statistically significant increase in tear production (Schirmer I test) was found in eyes that received more than 10 glands per graft compared with eyes that received fewer glands (χ(2) test; p=0.0096). Corneal transparency improved significantly in 11 (72.2%) eyes and corneal neovascularisation improved significantly in five eyes (29.4%) (McNemar test; p=0.001 and p=0.0005). The symptoms questionnaire revealed improvement in foreign body sensation in 53.6% of the patients, in photophobia in 50.2% and in pain in 54.8% (Kruskal-Wallis test; p=0.0167). Labial mucous membrane and minor salivary glands transplantation were found to constitute a good option for the treatment of severe symblepharon and dry eye secondary to SJS. This may be considered as a step prior to limbal stem cell and corneal transplantation in these patients.

Racial disparities in the risk of Stevens-Johnson Syndrome and toxic epidermal necrolysis as urate-lowering drug adverse events in the United States.

Science.gov (United States)

Lu, Na; Rai, Sharan K; Terkeltaub, Robert; Kim, Seoyoung C; Menendez, Mariano E; Choi, Hyon K

2016-10-01

HLA-B*5801 allele carriage (a strong determinant of allopurinol hypersensitivity syndrome) varies substantially among races, which may lead to racial disparities in the risk of Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) in the context of urate-lowering drug adverse events (ULDAEs). We examined this hypothesis in a large, racially diverse, and generalizable setting. Using a database representative of US hospitalizations (2009-2013), we investigated the racial distribution of hospitalized SJS/TEN (principal discharge diagnosis) as ULDAEs (ICD-9-CM Classification of External Causes). Our reference groups included the US Census population, US allopurinol users, and ULDAE hospitalizations without SJS/TEN. We identified 606 cases hospitalized for SJS/TEN as ULDAEs (mean age = 68 years; 44% male), among which there was an overrepresentation of Asians (27%) and Blacks (26%), and an underrepresentation of Whites (29%) and Hispanics (% too-low-to-report), compared with the US Census population (5%, 12%, 67%, and 15%, respectively). The hospitalization rate ratios for SJS/TEN among Asians, Blacks, and Whites were 11.9, 5.0, and 1.0 (referent), respectively. These associations persisted using other national referents. According to the NHANES 2009-2012, allopurinol constituted 96.8% of urate-lowering drug use, followed by probenecid (2.1%). These national data indicate that Asians and Blacks have a substantially higher risk of SJS/TEN as ULDAEs than Whites (or Hispanics), correlating well with corresponding frequencies of HLA-B*5801 in the US population (i.e., 7.4%, 4%, 1%, and 1%, respectively). Given its market dominance and established association with SJS/TEN, our findings support the use of vigilance in these minorities when considering allopurinol. Copyright © 2016 Elsevier Inc. All rights reserved.

50 CFR 697.25 - Adjustment to management measures.

Science.gov (United States)

2010-10-01

... of the Magnuson-Stevens Act, or to meet overfishing and rebuilding requirements of the Magnuson... consistent with the national standards of the Magnuson-Stevens Act, or to meet overfishing and rebuilding...

Stevens-Johnson syndrome and toxic epidermal necrolysis due to anticonvulsants share certain clinical and laboratory features with drug-induced hypersensitivity syndrome, despite differences in cutaneous presentations.

Science.gov (United States)

Teraki, Y; Shibuya, M; Izaki, S

2010-10-01

Drug-induced hypersensitivity syndrome (DIHS)/drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is characterized by late disease onset, fever, rash, hepatic dysfunction, haematological abnormalities, lymphadenopathy and often, human herpesvirus (HHV) reactivation. The diagnosis of DIHS is based on the combined presence of these findings. Anticonvulsants are a major cause of DIHS and may also cause Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). We examined whether SJS/TEN due to anticonvulsants display similar clinical and laboratory features seen in DIHS. Patients diagnosed with SJS or TEN due to anticonvulsants (n = 8) were examined and their clinical features and laboratory findings were compared with patients with anticonvulsant-related DIHS (n = 6). Seven of the eight patients with SJS/TEN developed symptoms > 3 weeks after starting anticonvulsants. Hepatic dysfunction was present in six patients with SJS/TEN and five patients with DIHS. Leucocytosis and/or eosinophilia was noted in seven patients with SJS/TEN and four patients with DIHS. Only one patient in the SJS/TEN group had atypical lymphocytosis; this was present in four patients with DIHS. Reactivation of HHV-6 was detected in one of the four patients tested in the SJS/TEN group, although it was seen in five of the six patients with DIHS. TSJS/TEN due to anticonvulsants may exhibit some clinical and laboratory features of DIHS. The nature of the cutaneous involvement should be emphasized in the diagnosis of DIHS. © 2009 The Author(s). Journal compilation © 2009 British Association of Dermatologists.

Cost Recovery Data Set

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The Magnuson-Stevens Fishery Conservation and Management Act (Magnuson-Stevens Act) requires NOAA’s National Marine Fisheries Service (NMFS) to collect fees to...

Case Report: Stevens-Johnson syndrome following a single double dosing of nevirapine-containing regimen once in an HIV-infected woman on long-term antiretroviral therapy.

Science.gov (United States)

Kakande, Betty; Isaacs, Thuraya; Muloiwa, Rudzani; Dlamini, Sipho; Lehloenya, Rannakoe

2015-01-01

A 31-year old HIV-infected African woman on nevirapine, tenofovir and lamivudine for more than 4 years presented with an 8-day history of symptoms and signs of Stevens-Johnson syndrome. She was on no other medication. Her viral load was undetectable and she had maintained a CD4 count of between 356 and 387cells/mm (3) in the preceding 2½ years. She missed her antiretrovirals 10 days before the onset of her symptoms and subsequently doubled her daily dose the following day. She had been on no other medication in the preceding 8 weeks. Her ARVs were stopped and she fully re-epithelialized with the exception of the lips, over the following 10 days. She was started on a daily single tablet of Odimune® (a fixed drug combination antiretroviral containing tenofovir, emtricitabine and efavirenz). Nevirapine is the most common offender in cases of antiretroviral-associated SJS in published literature. Lamivudine is very rarely implicated while there are no similar reports with tenofovir.  We concluded that nevirapine was by far the most likely offender in this case. Nevirapine toxicity is associated with high CD4 counts, undetectable viral load and high drug plasma level. We postulate that the sudden increase of the plasma levels of nevirapine in a patient with a high CD4 count and undetectable viral load created a perfect storm for the development of SJS in our patient, who had been on the NVP-containing regimen for many years. Clinicians should be aware that severe adverse drug reactions are dynamic and can occur even when the drug has been in use for a long time.

Evaluation of a Physiologically Based Pharmacokinetic (PBPK) Model Used to Develop Health Protective Levels for Trichloroethylene

Science.gov (United States)

2017-02-28

mice. Toxicol Sci 45(1): 33-41. Merdink, J.L., Stenner , R.D., Stevens, D.K., Parker, J.C. and Bull, R.J. 1999. Effect of enterohepatic circulation...Document RR-03-07. Stenner , R.D., Merdink, J.L., Stevens, D.K., Springer, D.L. and Bull, R.J. 1997. Enterohepatic recirculation of trichloroethanol...Pharmacol 123(1): 1-8. Templin, M.V., Stevens, D.K., Stenner , R.D., Bonate, P.L., Tuman, D. and Bull, R.J. 1995. Factors affecting species differences

Friending Brandeis: Privacy and Government Surveillance in the Era of Social Media

Science.gov (United States)

2012-06-01

The United States Institute of Peace, 2006. 35 Steven Kotler , “’Dark Web’ Project Takes on Cyber-Terrorism,” October 12, 2010, http...245 Gabriel, “Terror on the Internet: The New Arena, the New Challenge.” 246 Ibid., 218. 247 Steven Kotler , “’Dark...Washington Law School Pub. L. Research Paper No. 13, Harvard L. Rev. 119 (2005): 531. King v. U.S., 55 F.3rd 1193 (6th Cir. 1995). Kotler , Steven. “’Dark

Stability of epitheliotrophic factors in autologous serum eye drops from chronic Stevens-Johnson syndrome dry eye compared to non-autoimmune dry eye.

Science.gov (United States)

Phasukkijwatana, Nopasak; Lertrit, Patcharee; Liammongkolkul, Sompong; Prabhasawat, Pinnita

2011-09-01

To compare the concentrations of epitheliotrophic factors in autologous serum eye drops (ASE) prepared from sera of chronic Stevens-Johnson syndrome (SJS) patients with dry eyes to those prepared from non-autoimmune dry eye controls and to study the stability of the epitheliotrophic factors in different storage conditions. Twenty-percent ASE were prepared from 10 chronic SJS patients with dry eyes and 10 age-matched non-autoimmune dry eye controls. The concentrations of major epitheliotrophic factors comprising epidermal growth factor (EGF), transforming growth factor-beta1 (TGF-β1), transforming growth factor-beta2 (TGF-β2), and fibronectin in those ASE preparations were determined by enzyme-linked immunosorbent assay (ELISA) at baseline and after different storage conditions: at 4 °C for 1 week and 1 month; and at -20 °C for 1, 3 and 6 months. There were no significant differences in the concentrations of EGF, TGF-β1, TGF-β2 and fibronectin in 20% ASE between the SJS and control groups (EGF: 176.9 ± 40.9 vs. 185.5 ± 36.9 pg/mL, TGF-β1: 9.5 ± 2.1 vs. 9.5 ± 1.9 ng/mL, TGF-β2: 55.3 ± 30.0 vs. 63.91 ± 45.6 pg/mL and fibronectin: 70.5 ± 20.2 vs. 62.2 ± 21.3 µg/mL, respectively). These factors were stable at 4 °C for up to 1 month. Storage at -20 °C for up to 6 months resulted in a slight decrease in TGF-β1 (SJS: from 9.5-8.4 ng/mL, p dry eye patients, and that ASE should be sufficiently stable for up to 6 months, if stored properly at -20 °C.

Legitimating clinical research in the study of organizational culture

OpenAIRE

Schein, Edgar H.

1991-01-01

"Adapted from the text of the Sixteenth Annual Frederick J. Gaudet Lecture, sponsored by the Stevens Chapter of Psi Chi, The National Honor Society in Psychology, Stevens Institute, Hoboken, N.J., April 30, 1991"--P. 1.

Stroke, tPA, and Physician Decision-Making

Science.gov (United States)

... MD Steven Karceski, MD Stroke, tPA, and physician decision-making Dominic Hovsepian, BS Steven Karceski, MD WHAT DID ... has not been carefully studied is the physician ’ s decision-making process. It was because of this that Dr. ...

76 FR 57712 - Performance Review Board Membership

Science.gov (United States)

2011-09-16

... DEPARTMENT OF COMMERCE Performance Review Board Membership AGENCY: Economics and Statistics... the Performance Review Board (PRB) in accordance with the Economics and Statistics Administration's.... Bostic, Jr., Arnold A. Jackson, Theodore A. Johnson, Steven J. Jost, J. Steven Landefeld, Jennifer Madans...

Modeling Synergies in Large Human-Machine Networked Systems

Science.gov (United States)

2013-09-25

Agents and Multi- Agent Systems (AAMAS), Valencia, Spain, June 4-8, 2012. Steven Okamoto_, Praveen Paruchuri, Yonghong Wang, Katia Sycara, Janusz...Society, Santa Monica, CA: Human Factors and Ergonomics Society. 86. Steven Okamoto_, Praveen Paruchuri, Yonghong Wang, Katia Sycara, Janusz

Large-scale Heterogeneous Network Data Analysis

Science.gov (United States)

2012-07-31

Steven Spielberg Vincent Price Buster Keaton Harry Ritz Robert Duvall (2) Results for Role-based Entity Clustering We validate our role-based entity...Connery Jeanette Macdonal d Robert Benchley 1 0 Vincent Price Steven Spielberg Vincent Price Buster Keaton Harry Ritz Robert Duvall

Johnson syndrome in a Nigerian woman with chronic lymphocytic ...

African Journals Online (AJOL)

Stevens-Johnson syndrome is an adverse muco-cutaneous complication arising from a number of conditions which include the administration of some drugs. A female Nigerian with chronic lymphocytic leukaemia, (Binet stage C) who developed Stevens-Johnson syndrome following commencement of allopurinol is ...

How Do the Metabolic Effects of Chronic Stress Influence Breast Cancer Biology?

Science.gov (United States)

2012-04-01

Paul A. Volden, Erin L. Wonder, Maxwell N. Skor, Christopher M. Carmean, Honggang Ye, Masha Kocherginsky, Eleanor Smith, Steven Kregel, Martha K...Wonder, Maxwell N. Skor, Christopher M. Carmean, Honggang Ye, Masha Kocherginsky, Steven Kregel, Martha K. McClintock, Matthew J. Brady, and Suzanne

50 CFR 679.1 - Purpose and scope.

Science.gov (United States)

2010-10-01

... Purpose and scope. Regulations in this part were developed by the Council under the Magnuson-Stevens... activities that will result in an ongoing, regionally based, fisheries-related economy. (f) Groundfish... measures. Regulations in this part were developed by NMFS and the Council under the Magnuson-Stevens Act...

Don't Forget about Pragmatics!

DEFF Research Database (Denmark)

Albinus, Lars

2016-01-01

A Commentary on the heading article "The Philosophy and Semantics of the Cognitive Science of Religion" by Steven Engler and Mark Q. Gardiner......A Commentary on the heading article "The Philosophy and Semantics of the Cognitive Science of Religion" by Steven Engler and Mark Q. Gardiner...

76 FR 76980 - Notice of Listing of Members of the Food and Drug Administration's Senior Executive Service...

Science.gov (United States)

2011-12-09

...'Tonya Davis Sheryl Lard-Whiteford David Elder Murray Lumpkin Denise Esposito William Maisel Tracy Forfa... Steven Solomon Daniel McChesney Stephen Spielberg William McConagha Roberta Wagner Patrick McGarey David... Murphy Donald Zink Melinda Plaisier Lynne Rice Mark Roh James Sigg Steven Silverman Howard Sklamberg...

Strong Artificial Intelligence and National Security: Operational and Strategic Implications

Science.gov (United States)

2015-05-18

Directed by Steven Spielberg , Performed by Haley Joel Osment, Jude Law, William Hurt, Frances O’Connor and Sam Robards. 16 well-structured, and ill...Artificial Intelligence. Directed by Steven Spielberg . Performed by Haley Joel Osment, Jude Law, William Hurt, Frances O’Connor and Sam Robards

Keystone Symposia on Epigenomics and Chromatin Dynamics

DEFF Research Database (Denmark)

Ravnskjær, Kim

2012-01-01

Keystone Symposia kicked off the start of 2012 with two joint meetings on Epigenomics and Chromatin Dynamics and a star-studded list of speakers. Held in Keystone, CO, January 17-22, and organized by Steven Jacobsen and Steven Henikoff and by Bradley Cairns and Geneviève Almouzni, respectively...

Interactive Model-Centric Systems Engineering (IMCSE) Phase 5

Science.gov (United States)

2018-02-28

Interactive Model-Centric Systems Engineering (IMCSE) Phase 5 Technical Report SERC-2018-TR-104 Feb 28, 2018 Principal Investigator...Date February 28, 2018 Copyright © 2018 Stevens Institute of Technology, Systems Engineering ...Research Center The Systems Engineering Research Center (SERC) is a federally funded University Affiliated Research Center managed by Stevens

76 FR 16806 - Notice of Intent To Prepare an Environmental Impact Statement and Environmental Impact Report for...

Science.gov (United States)

2011-03-25

... in advance through local media, newspapers and the BLM Web site at: http://www.blm.gov/ca/st/en/fo...: Casa Diablo IV Development Project, C/O Steven Nelson, Project Manager. Documents pertinent to this... National Forest, telephone (760) 873- 2424; or mail to: Steven Nelson, Project Manager, BLM [[Page 16807...

Resonance – Journal of Science Education | Indian Academy of ...

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education. Prasad Perlekar. Articles written in Resonance – Journal of Science Education. Volume 21 Issue 5 May 2016 pp 395-400 General Article. Steven Vogel (1940-2015) · Prasad Perlekar Rajaram Nityananda · More Details Abstract Fulltext PDF. Steven Vogel was a ...

The Great American Divide: The Military-Civilian Gap

Science.gov (United States)

2012-03-14

Steven A. Bank, Kirk J. Stark, and Joseph J. Thorndike provide a historical account of America’s war-time fiscal policies for the major American wars...accessed January 16, 2012). 63 Steven A. Bank, Kirk J. Stark, Joseph J. Thorndike , War and Taxes (Washington, DC: The Urban Institute Press, 2008

Force Structure Matters: The US Field Artillery in Operational Art

Science.gov (United States)

2015-05-23

2003 (Fort Sill, OK: US Army Field Artillery Center, 2004), 62-63. 3 Sean Bateman and Steven Hady, “King of Battle Once Again: An Organizational...To What Ends Military Power?” International Security 4, no. 4 (Spring 1980): 3- 35. Bateman , Sean and Steven Hady. “King of Battle Once Again: An

White House Communications Agency (WHCA) Presidential Voice Communications Rack Mount System Mechanical Drawing Package

Science.gov (United States)

2015-12-01

Rack Mount System Mechanical Drawing Package by Steven P Callaway Approved for public release; distribution unlimited...Laboratory White House Communications Agency (WHCA) Presidential Voice Communications Rack Mount System Mechanical Drawing Package by Steven P...Note 3. DATES COVERED (From - To) 04/2013 4. TITLE AND SUBTITLE White House Communications Agency (WHCA) Presidential Voice Communications Rack

Storytelling for a Nation

DEFF Research Database (Denmark)

Schubart, Rikke

2007-01-01

The article analyzes the use of memory and history in Steven Spielberg's war films Schindler's List (1993), Saving Private Ryan (1998) og tv-serien Band of Brothers (2001)......The article analyzes the use of memory and history in Steven Spielberg's war films Schindler's List (1993), Saving Private Ryan (1998) og tv-serien Band of Brothers (2001)...

Two Sides of the Same Coin: Leadership.

Science.gov (United States)

Berg, Steven; Burns, James MacGregor; McKay, Ritchie

2002-01-01

This article presents a transcript of Steven Berg's interviews with James MacGregor Burns and Ritchie McKay regarding leadership. James Burns is a senior fellow in the Jepson School of Leadership Studies at the University of Richmond, Virginia. Ritchie McKay is Head Coach of the men's basketball team at University of New Mexico. Steven Berg is an…

An Interview with Steven Millhauser

Directory of Open Access Journals (Sweden)

Étienne Février

2012-01-01

Full Text Available Etienne Février : I would like to begin this interview with a question about architecture. Images of architecture appear frequently in your fiction, from Martin Dressler to more recent collections like Dangerous Laughter. In that collection’s “thirteen stories,” we find a tower reaching all the way to heaven, a life-size replica of a town so precise that even the “levels of salt in the saltshakers” match those of the original town, and a series of outwardly expanding domes—covering a house, f...

Hollywoodbloggen: Jeg elsker Hollywoodfilm

DEFF Research Database (Denmark)

Schubart, Rikke

2009-01-01

En introduktion til Hollywoodbloggen på videnskab.dk med første indlæg om hollywoodfilmens alsidighed fra Van Damme til Schindler's List af Steven Spielberg Udgivelsesdato: 27 januar......En introduktion til Hollywoodbloggen på videnskab.dk med første indlæg om hollywoodfilmens alsidighed fra Van Damme til Schindler's List af Steven Spielberg Udgivelsesdato: 27 januar...

Basic Cognitive Neuroscience of Memory and Self-Appraisals in PTSD

Science.gov (United States)

2014-02-01

PTSD study and the Steven and Alexandra Cohen Veterans Center for the Study for Post - Traumatic Stress Disorder ... Post - Traumatic Stress Disorder and Traumatic Brain Injury recruitment protocol. All subjects participating in an MRI scan are required to provide...include subjects from the Steven and Alexandra Cohen Veterans Center for the Study for Post - Traumatic Stress Disorder and Traumatic Brain Injury who

Data on the densification during sintering of binder jet printed samples made from water- and gas-atomized alloy 625 powders

Directory of Open Access Journals (Sweden)

Amir Mostafaei

2017-02-01

Full Text Available Binder jet printing (BJP is a metal additive manufacturing method that manufactures parts with complex geometry by depositing powder layer-by-layer, selectively joining particles in each layer with a polymeric binder and finally curing the binder. After the printing process, the parts still in the powder bed must be sintered to achieve full densification (A. Mostafaei, Y. Behnamian, Y.L. Krimer, E.L. Stevens, J.L. Luo, M. Chmielus, 2016; A. Mostafaei, E. Stevens, E. Hughes, S. Biery, C. Hilla, M. Chmielus, 2016; A. Mostafaei, Y. Behnamian, Y.L. Krimer, E.L. Stevens, J.L. Luo, M. Chmielus, 2016 [1–3]. The collected data presents the characterization of the as-received gas- and water-atomized alloy 625 powders, BJP processing parameters and density of the sintered samples. The effect of sintering temperatures on the microstructure and the relative density of binder jet printed parts made from differently atomized nickel-based superalloy 625 powders are briefly compared in this paper. Detailed data can be found in the original published papers by authors in (A. Mostafaei, J. Toman, E.L. Stevens, E.T. Hughes, Y.L. Krimer, M. Chmielus, 2017 [4].

China’s Interests in Afghanistan: Current Projects and Future Prospects

Science.gov (United States)

2013-12-01

49 Derek Scissors and Steven Bucci. “China Cyber Threat: Huawei and American Policy Toward Chinese Companies.” The...Heritage Foundation, no. 3761, October 23, 2012, http://www.heritage.org/research/reports/2012/10/china-cyber-threat- huawei -and-american-policy-toward...try- to-avoid-a-cold-war-mentality.html?pagewanted=all. 113 Scissors, Derek, and Steven Bucci. “China Cyber Threat: Huawei and American Policy

Reviews of recent publications

Directory of Open Access Journals (Sweden)

various authors

1993-06-01

Full Text Available Granqvist, Raoul, editor. Canonization and Teaching of African Literature. Matatu 7 by Claire L. Dehon Margolis, Joseph. Texts Without Referents: Reconciling Science and Narrative by David J. Depew Keitel, Evelyne. Reading Psychosis, Readers, Texts and psychoanalysis by Reinhild Steingrover Shaviro, Steven. Passion and excess: Blanchot, Bataille, and Literary Theory by Steven Ungar Kellner, Douglas. Jean Baudrillard From Marxism to Postmodernism and Beyond by Allan Stoeld Pecorora, Vincent P. Self & Form in Modern Narrative by Walter A. Strauss Jordan, Barry. Writers and Politics in Franco's Spain by Salvador J. Fajardo Motard-Noar, Martine. Les Fictions d'Hélène Cixous. Une autre lanque de femme by Randi Brox Birn Alexandrov, Vladimir E. Nabokov's Otherworld by Dale E. Peterson Baker, Peter. Obdurate Brilliance: Exteriority and the Modern Long Poem by Steven Winspur

Qualitative Considerations of Nuclear Forces at Lower Numbers and Implications for Future Arms Control Negotiations

Science.gov (United States)

2012-07-01

source of dangerous and confused policy guidance. Pifer, Steven, Richard C. Bush, Vanda Felbab- Brown , Martin S. Indyk, Michael O’Hanlon and Kenneth M...Japanese hedging option, while progressives, including Gareth Evans, are committed to global reductions of nuclear weapons. South Korea is primarily...September 2009. http://www.mda.mil/global/documents/pdf/paa.pdf Pifer, Steven, Richard C. Bush, Vanda Felbab- Brown , Martin S. Indyk, Michael E

Reforming Military Command Arrangements: The Case of the Rapid Deployment Joint Task Force

Science.gov (United States)

2011-03-01

protected. Organizational theory has identified actions that organizations normally pursue or avoid in order to increase—or at least preserve—their...thesis. See note 1 for details. 85 179. Jeffrey W. Taliaferro, Steven E. Lobell, and Norrin M. Ripsman, “Introduction: Neoclassical Realism, the State...and For- eign Policy,” in Steven E. Lobell, Norrin M. Ripsman and Jeffrey W. Taliaferro, eds., Neoclassical Realism, the State, and Foreign Poli- cy

Documentation and Analysis of the ’Miscellaneous’ Account Category within the DoD Instruction 7220.29-H Depot Level Maintenance Cost Accounting System.

Science.gov (United States)

1984-12-01

34MISCELLANEOUS" ACCOUNT CATEGORY WITHIN THE DOD INSTRUCTION 7220.29-H DEPOT LEVEL MAINTENANCE COST ACCOUNTING SYSTEM by a. Steven Eugene Lehr CDecember 1984...PERFORMING ONG. REPORT NUMBER Maintenance Cost Accounting System 7. AUTHOR(&) S. CONTRACT OR GRANT NUMBER(@) Steven Eugene Lehr 9. PERFORMING ORGANIZATION...Availability Codes IS. KEY WORDS (Continue on reverse *ids It necessary and Identify by block number) Dvi Special Uniform Cost Accounting System DoD

A Study of the Effect of Interrupted Quenches on a Thermomechanically Processed High Carbon Steel.

Science.gov (United States)

1982-10-01

steel . Successful martempering requires a cooling rate sufficient to avoid the nose of the C- curve and thus prevent significant bainite formation. When...STUDY OF THE EFFECT OF INTERRUPTED QUENCHES ON A THERMONECHANICALLY PROCESSED HIGH CARBON STEEL by Steven A. Barton October 1982 Thesis Advisor: T.R...unlimited. A Study of the Effect of Interrupted Quenches on a Thermomechanically Processed High Carbon Steel by Steven A. Barton Lieutenant, United

Helium Nanodroplet Isolation and Infrared Spectroscopy of the Isolated Ion-Pair 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide

Science.gov (United States)

2013-09-01

Isolated Ion- Pair 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide   Emmanuel I. Obi†, Christopher M. Leavitt†, Paul L. Raston... Christopher P. Moradi†, Steven D.   Flynn†, Jerry A. Boatz§,*, Steven D. Chambreau‡,* and Gary E. Douberly†,*     †Department of Chemistry, University of...Windus, T. L.; Dupuis , M.; Montgomery, J. A. General Atomic and Molecular Electronic-Structure System. J. Comput. Chem. 1993, 14, 1347-1363

Øjnene der ser

DEFF Research Database (Denmark)

Pedersen, Peter Ole

2017-01-01

Filmhistorisk artikel om fremstillingen af overvågning i science fiction-genren fra 1920 og frem til nutidige værker som bl.a. Steven Spielbergs Minority Report og George Lucas nyklassiker THX 1138......Filmhistorisk artikel om fremstillingen af overvågning i science fiction-genren fra 1920 og frem til nutidige værker som bl.a. Steven Spielbergs Minority Report og George Lucas nyklassiker THX 1138...

High Productivity Computing Systems and Competitiveness Initiative

Science.gov (United States)

2007-07-01

digital animation industry, which is drawing audiences around the world, and profits for the U.S. entertainment sector. Leonard explained to attendees... audiences in large part because a range of HPC hardware and software tools enabled filmmakers to control subtle aspects of lighting to characters’ fur and...Blackstone Group Harold J. Raveché Stevens Institute of Technology Steven S Reinemund Pepsi -Cola Company Judith Rodin University of Pennsylvania Allen B

Synthesizing Graphene Production with Polymeric Injection Molding for Enhancing EMI Shielding Effectiveness of Plastics

Science.gov (United States)

2017-09-01

Ulrich, Karl T., and Steven D. Eppinger. 2012. Product Design and Development, 5th ed. New York: McGraw-Hill Irwin. Warner, Jamie H., Franziska Schaffel...of tasks that an organization or business generally follows to transform a thought or idea of a product to a manufactured good. In the early stages...established product design and development processes. Karl Ulrich and Steven Eppinger (2012) state that one of the initial steps in the opportunity

Local Geoid Determination Using the Global Positioning System

Science.gov (United States)

1988-09-01

Positioning System by Ma, Wei-Ming September 1988 Co-Advisor: Kandiah Jeyapalan Co-Advisor: Stevens P. Tucker Approved for public release; distribution is... Jeyapalan and Stevens P. Tucker, my thesis advisors, for their dedicated assistance and guidance during the study. Without their encouragement...method of collocation is [ Jeyapalan , 1977]: x = A*X+S +n +O.S q q P where x the vector of the observation (x = Ah - N0(X,Y,Z) - H) A a given rectangular

Kamikaze Paksas appoints Borisov / Steven Paulikas

Index Scriptorium Estoniae

Paulikas, Steven

2004-01-01

Leedu presidendi Rolandas Paksase ümber vallandunud skandaali üks võtmeisikuid, Vene kodanik Juri Borissov teatas, et hakkab tööle presidendi ühiskondliku nõunikuna, mõni tund hiljem otsustas president distantseeruda oma valimiskampaania suursponsorist

Dr. Steven Chu, Secretary of Energy

Science.gov (United States)

addiction to foreign oil, address the global climate crisis and create millions of new jobs. Prior to his , the Korean Academy of Sciences and Technology and numerous other civic and professional organizations

MX: Milestone II. Final Environmental Impact Statement. Volume 6. Public Comments

Science.gov (United States)

1978-10-06

8217VPaoli, molyore, ’leming# Daily, Otis, AKrun, Brus , LcKley, "ray, Jos, Id~lia, and Vernon. Thjen tncrc are a nuuber ul CceUCeerleS in tebween witl Ourialz...KS Public Comments VI - 5-101 Grace Eastin Yuma, CO M. H. Eaton Oakley, KS Mr. Dan R. Ebener Dubuque, IA Mr. Tom Eberhart Burlington, CO Elizabeth ...Russell Springs, KS Burlington, CO Rebecca L. Smith Mrs. Elizabeth StevensWinona, KS Potter, NE * r. Ronald L. Smith Mr. Wesley L. Stevens Winona, KS

Cap the Chameleon: A Review of Captain America, Masculinity, and Violence

OpenAIRE

Clarke Gray, Brenna

2017-01-01

'Captain America, Masculinity, and Violence: The Evolution of a National Icon', by J. Richard Stevens, Syracuse University Press, 376 pages, 6 . 9, 2015, ISBN 978-0-8156-3395-2; ebook 978-0-8156-5320-2 This article favourably reviews' Captain America, Masculinity, and Violence: The Evolution of a National Icon' (Stevens 2015) and offers some suggestions for further research. The review explores the ways in which the book offers insights into one of the most popular characters in comics and a...

Case Report: Stevens-Johnson syndrome following a single double dosing of nevirapine-containing regimen once in an HIV-infected woman on long-term antiretroviral therapy. [version 1; referees: 1 approved, 2 approved with reservations

Directory of Open Access Journals (Sweden)

Betty Kakande

2015-06-01

Full Text Available A 31-year old HIV-infected African woman on nevirapine, tenofovir and lamivudine for more than 4 years presented with an 8-day history of symptoms and signs of Stevens-Johnson syndrome. She was on no other medication. Her viral load was undetectable and she had maintained a CD4 count of between 356 and 387cells/mm3 in the preceding 2½ years. She missed her antiretrovirals 10 days before the onset of her symptoms and subsequently doubled her daily dose the following day. She had been on no other medication in the preceding 8 weeks. Her ARVs were stopped and she fully re-epithelialized with the exception of the lips, over the following 10 days. She was started on a daily single tablet of Odimune® (a fixed drug combination antiretroviral containing tenofovir, emtricitabine and efavirenz.   Nevirapine is the most common offender in cases of antiretroviral-associated SJS in published literature. Lamivudine is very rarely implicated while there are no similar reports with tenofovir.  We concluded that nevirapine was by far the most likely offender in this case. Nevirapine toxicity is associated with high CD4 counts, undetectable viral load and high drug plasma level. We postulate that the sudden increase of the plasma levels of nevirapine in a patient with a high CD4 count and undetectable viral load created a perfect storm for the development of SJS in our patient, who had been on the NVP-containing regimen for many years. Clinicians should be aware that severe adverse drug reactions are dynamic and can occur even when the drug has been in use for a long time.

A Burst-Mode Photon-Counting Receiver with Automatic Channel Estimation and Bit Rate Detection

Science.gov (United States)

2016-02-24

Grein, M.E., Elgin, L.E., Robinson, B.S., Kachelmyer, A.L., Caplan , D.O., Stevens, M.L., Carney, J.J., Hamilton, S.A., and Boroson, D.M., “Demonstration...Robinson, B.S., Kerman, A.J., Dauler, E.A., Barron, R.J., Caplan , D.O., Stevens, M.L., Carney, J.J., Hamilton, S.A., Yang, J.K.W., and Berggren, K.K., “781...Mbit/s photon-counting optical communications using a superconducting nanowire detector,” Optics Letters, v. 31 no. 4 444-446 (2006). [14] Caplan

An analysis of Monte Carlo tree search

CSIR Research Space (South Africa)

James, S

2017-02-01

Full Text Available Tree Search Steven James∗, George Konidaris† & Benjamin Rosman∗‡ ∗University of the Witwatersrand, Johannesburg, South Africa †Brown University, Providence RI 02912, USA ‡Council for Scientific and Industrial Research, Pretoria, South Africa steven....james@students.wits.ac.za, gdk@cs.brown.edu, brosman@csir.co.za Abstract Monte Carlo Tree Search (MCTS) is a family of directed search algorithms that has gained widespread attention in re- cent years. Despite the vast amount of research into MCTS, the effect of modifications...

Paranoia på Film

DEFF Research Database (Denmark)

Pedersen, Peter Ole

Filmbog med hovedfokus på temaet overvågning i thriller og science fiction-genren. Gennem omfattende analyser af Francis Ford Coppolas The Conversation (1974), David Finchers Panic Room (2002), George Lucas THX 1138 (1971) og Steven Spielbergs Minority Report (2002) gives kritisk bud på populærfi......Filmbog med hovedfokus på temaet overvågning i thriller og science fiction-genren. Gennem omfattende analyser af Francis Ford Coppolas The Conversation (1974), David Finchers Panic Room (2002), George Lucas THX 1138 (1971) og Steven Spielbergs Minority Report (2002) gives kritisk bud på...

Science.gov (United States)

Medina Arnaudo, Gisel Ivana

2017-09-08

Resumen: La valoración del Índice de Filtrado Glomerular (IFG) es fundamental para la selección de potenciales donantes renales. Para su medición existen métodos poco prácticos y complejos, por lo cual se han desarrollado ecuaciones de estimación del IFG. Objetivo: Evaluar el rendimiento diagnóstico de ecuaciones de estimación del IFG a partir de Creatinina y Cistatina C en una población de adultos sanos candidatos a donantes renales. Materiales y métodos: Se llevó a cabo un estudio transversal en 72 pacientes de ambos sexos de entre 18 y 75 años de edad, candidatos a donantes renales. Se les midió el IFG a través del clearance de Iotalamato no marcado (IFGm). Se evaluaron cuatro ecuaciones de estimación del FG (IFGe): MDRD, del estudio "Modification of Diet in Renal Disease"; CKD-EPI-Creatinina (CKD-EPI-CREAT) y CKD-EPI-Creatinina y Cistatina C (CKD-EPI-CREAT+CIS), desarrolladas por el grupo "Chronic Kidney Disease Epidemiology Collaboration"; y la que incluye Creatinina y Cistatina C propuesta por Stevens y col. (STEVENS-CREAT+CIS). Se analizó el desempeño de cada ecuación con respecto al IFGm. Resultados: Las ecuaciones CKD-EPI-CREAT+CIS, STEVENS-CREAT+CIS y CKD-EPI-CREAT mostraron ser más exactas (bias= 1,93; -0,71; -1,53 mL/min/1,73m2 respectivamente) que MDRD (bias= -10,36 mL/min/1,73m2). El mejor rendimiento diagnóstico lo mostró  el IFGe CKD-EPI-CREAT+CIS (LR(+)=9,8; "Positive Likelihood Ratios"), seguido por IFGe STEVENS-CREAT+CIS (LR(+)=4,7) y luego por IFGe CKD-EPI-CREAT (LR(+)=3,7). Discusión: Las ecuaciones CKD-EPI-CREAT+CIS, STEVENS-CREAT+CIS y CKD-EPI-CREAT demostraron tener un desempeño claramente superior a MDRD para estimar el IFG en la población estudiada.

Cost-effectiveness analysis of HLA-B*58: 01 genetic testing before initiation of allopurinol therapy to prevent allopurinol-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in a Malaysian population.

Science.gov (United States)

Chong, Huey Yi; Lim, Yi Heng; Prawjaeng, Juthamas; Tassaneeyakul, Wichittra; Mohamed, Zahurin; Chaiyakunapruk, Nathorn

2018-02-01

Studies found a strong association between allopurinol-induced Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) and the HLA-B*58:01 allele. HLA-B*58:01 screening-guided therapy may mitigate the risk of allopurinol-induced SJS/TEN. This study aimed to evaluate the cost-effectiveness of HLA-B*58:01 screening before allopurinol therapy initiation compared with the current practice of no screening for Malaysian patients with chronic gout in whom a hypouricemic agent is indicated. This cost-effectiveness analysis adopted a societal perspective with a lifetime horizon. A decision tree model coupled with Markov models were developed to estimate the costs and outcomes, represented by quality-adjusted life years (QALYs) gained, of three treatment strategies: (a) current practice (allopurinol initiation without HLA-B*58:01 screening); (b) HLA-B*58:01 screening before allopurinol initiation; and (c) alternative treatment (probenecid) without HLA-B*58:01 screening. The model was populated with data from literature review, meta-analysis, and published government documents. Cost values were adjusted for the year 2016, with costs and health outcomes discounted at 3% per annum. A series of sensitivity analysis including probabilistic sensitivity analysis were carried out to determine the robustness of the findings. Both HLA-B*58:01 screening and probenecid prescribing were dominated by current practice. Compared with current practice, HLA-B*58:01 screening resulted in 0.252 QALYs loss per patient at an additional cost of USD 322, whereas probenecid prescribing resulted in 1.928 QALYs loss per patient at an additional cost of USD 2203. One SJS/TEN case would be avoided for every 556 patients screened. At the cost-effectiveness threshold of USD 8695 per QALY, the probability of current practice being the best choice is 99.9%, in contrast with 0.1 and 0% in HLA-B*58:01 screening and probenecid prescribing, respectively. This is because of the low incidence of

Is phenytoin contraindicated in patients receiving cranial irradiation?

Energy Technology Data Exchange (ETDEWEB)

Borg, M.F. [Royal Adelaide Hospital, SA (Australia); Probert, J.C. [Auckland Hospital, Auckland (New Zealand). Dept. of Radiation Oncology; Zwi, L.J. [Auckland Univ. (New Zealand). Dept. of Medicine and Surgery

1995-02-01

Three recent publications have reported the development of erythema multiforme and Stevens-Johnson syndrome in patients receiving cranial irradiation and sodium phenytoin. Some authors have recommended that patients receiving whole brain radiation therapy and who have had seizures should not be prescribed phenytoin but an alternative anticonvulsant. This article reviews the current literature pertaining to the development of this potentially lethal complication in patients receiving whole brain radiation and phenytoin, with reference to the single recorded case of Stevens-Johnson syndrome in a patient receiving cranial irradiation and phenytoin in Auckland, New Zealand. While the clinical picture in the 16 patients reported in the literature and the current case report differed from the classical form of erythema multiforme, a similar pattern of presentation and outcome appeared in all patients reviewed, suggesting that the combination of phenytoin, cranial irradiation and the gradual reduction of concomitant steroids seem to lead to the development of erythema multiforme and/or Stevens-Johnson syndrome. The data presented, although sparse, suggest that phenytoin should not be prescribed in patients receiving cranial irradiation. 21 refs., 2 tabs., 3 figs.

Is phenytoin contraindicated in patients receiving cranial irradiation?

International Nuclear Information System (INIS)

Borg, M.F.; Probert, J.C.; Zwi, L.J.

1995-01-01

Three recent publications have reported the development of erythema multiforme and Stevens-Johnson syndrome in patients receiving cranial irradiation and sodium phenytoin. Some authors have recommended that patients receiving whole brain radiation therapy and who have had seizures should not be prescribed phenytoin but an alternative anticonvulsant. This article reviews the current literature pertaining to the development of this potentially lethal complication in patients receiving whole brain radiation and phenytoin, with reference to the single recorded case of Stevens-Johnson syndrome in a patient receiving cranial irradiation and phenytoin in Auckland, New Zealand. While the clinical picture in the 16 patients reported in the literature and the current case report differed from the classical form of erythema multiforme, a similar pattern of presentation and outcome appeared in all patients reviewed, suggesting that the combination of phenytoin, cranial irradiation and the gradual reduction of concomitant steroids seem to lead to the development of erythema multiforme and/or Stevens-Johnson syndrome. The data presented, although sparse, suggest that phenytoin should not be prescribed in patients receiving cranial irradiation. 21 refs., 2 tabs., 3 figs

Cap the Chameleon: A Review of 'Captain America, Masculinity, and Violence'

Directory of Open Access Journals (Sweden)

Brenna Clarke Gray

2017-11-01

Full Text Available 'Captain America, Masculinity, and Violence: The Evolution of a National Icon', by J. Richard Stevens, Syracuse University Press, 376 pages, 6 . 9, 2015, ISBN 978-0-8156-3395-2; ebook 978-0-8156-5320-2 This article favourably reviews' Captain America, Masculinity, and Violence: The Evolution of a National Icon' (Stevens 2015 and offers some suggestions for further research. The review explores the ways in which the book offers insights into one of the most popular characters in comics and also gestures towards the work scholars of mainstream American superhero comics must tackle in the future.

Paksas declares candidacy amid uncertainty / Steven Paulikas

Index Scriptorium Estoniae

Paulikas, Steven

2004-01-01

Leedu ametieetika peakomisjon otsustas, et ametist tagandatud ekspresident Rolandas Paksas ei saa kolm aastat riigiametites töötada. See otsus võib takistada Paksase kandideerimist ennetähtaegsetel presidendivalimistel. Vt. samas: And here's the competition...

Steven's orbital reduction factor in ionic clusters

Science.gov (United States)

Gajek, Z.; Mulak, J.

1985-11-01

General expressions for reduction coefficients of matrix elements of angular momentum operator in ionic clusters or molecular systems have been derived. The reduction in this approach results from overlap and covalency effects and plays an important role in the reconciling of magnetic and spectroscopic experimental data. The formulated expressions make possible a phenomenological description of the effect with two independent parameters for typical equidistant clusters. Some detailed calculations also suggest the possibility of a one-parameter description. The results of these calculations for some ionic uranium compounds are presented as an example.

Mayoral controversy resurrects political hostility / Steven Paulikas

Index Scriptorium Estoniae

Paulikas, Steven

2004-01-01

Vilniuse linnapea Arturas Zuokas kuulati üle seoses võimaliku häälteostmisega kohalike omavalitsuste valimistel. A. Zuokas peab ülekuulamise põhjuseks president Rolandas Paksase survet uurimisorganitele

Government promises billions for highways / Steven Paulikas

Index Scriptorium Estoniae

Paulikas, Steven

2004-01-01

Läti transpordiministeerium avaldas riigi teedevõrgu arengukava järgmiseks 25 aastaks, mille kohaselt investeeritakse maanteede ja raudteede ehitusse kuni 18 miljardit litti. Leedu transpordiettevõtjate hinnangul ei ole uued suuremahulised projektid majandusarengu seisukohalt vajalikud

04 Stevens & Terblanché - Sustainable agriculture develop…

African Journals Online (AJOL)

annaline

group development and social capital formation. .... This model of group development is therefore a successive-stage theory as it ... learning or development. .... Bandura (1986) stated that group efficacy “ will influence what people will do as a.

Delaware's first serial killer.

Science.gov (United States)

Inguito, G B; Sekula-Perlman, A; Lynch, M J; Callery, R T

2000-11-01

The violent murder of Shirley Ellis on November 29, 1987, marked the beginning of the strange and terrible tale of Steven Bryan Pennell's reign as the state of Delaware's first convicted serial killer. Three more bodies followed the first victim, and all had been brutally beaten and sadistically tortured. The body of a fifth woman has never been found. State and county police collaborated with the FBI to identify and hunt down their suspect, forming a task force of over 100 officers and spending about one million dollars. Through their knowledge and experience with other serial killers, the FBI was able to make an amazingly accurate psychological profile of Delaware's serial killer. After months of around-the-clock surveillance, Steven Pennell was arrested on November 29, 1988, one year to the day after the first victim was found. Pennell was found guilty in the deaths of the first two victims on November 29, 1989, and plead no contest to the murder of two others on October 30, 1991. Still maintaining his innocence, he asked for the death penalty so that he could spare his family further agony. Steven Pennell was executed by lethal injection on March 15, 1992.

Hydrogeologic framework, groundwater and surface-water systems, land use, pumpage, and water budget of the Chamokane Creek basin, Stevens County, Washington

Science.gov (United States)

Kahle, Sue C.; Taylor, William A.; Lin, Sonja; Sumioka, Steven S.; Olsen, Theresa D.

2010-01-01

A study of the water resources of the unconsolidated groundwater system of the Chamokane Creek basin was conducted to determine the hydrogeologic framework, interactions of shallow and deep parts of the groundwater system with each other and the surface-water system, changes in land use and land cover, and water-use estimates. Chamokane Creek basin is a 179 mi2 area that borders and partially overlaps the Spokane Indian Reservation in southern Stevens County in northeastern Washington State. Aquifers within the Chamokane Creek basin are part of a sequence of glaciofluvial and glaciolacustrine sediment that may reach total thicknesses of about 600 ft. In 1979, most of the water rights in the Chamokane Creek basin were adjudicated by the United States District Court requiring regulation in favor of the Spokane Tribe of Indians' senior water right. The Spokane Tribe, the State of Washington, and the United States are concerned about the effects of additional groundwater development within the basin on Chamokane Creek. Information provided by this study will be used to evaluate the effects of potential increases in groundwater withdrawals on groundwater and surface-water resources within the basin. The hydrogeologic framework consists of six hydrogeologic units: The Upper outwash aquifer, the Landslide Unit, the Valley Confining Unit, the Lower Aquifer, the Basalt Unit, and the Bedrock Unit. The Upper outwash aquifer occurs along the valley floors of the study area and consists of sand, gravel, cobbles, boulders, with minor silt and (or) clay interbeds in places. The Lower aquifer is a confined aquifer consisting of sand and gravel that occurs at depth below the Valley confining unit. Median horizontal hydraulic conductivity values for the Upper outwash aquifer, Valley confining unit, Lower aquifer, and Basalt unit were estimated to be 540, 10, 19, and 3.7 ft/d, respectively. Many low-flow stream discharge measurements at sites on Chamokane Creek and its tributaries

Reconstructing the Past as a Means of Rationalizing the Present: A Study of Kazuo Ishiguro’s The Remains of The Day (1989

Directory of Open Access Journals (Sweden)

Mohamed Fathi Helaly Khalaf

2017-05-01

Full Text Available The postwar world period was riddled with rapid changes at the different levels. Many people felt they were not able to come to terms with such ongoing changes and had to find a way to coexist with the status-quo. Postmodernism looks upon man as a social being that should learn how to adapt himself to whatever situation by whatever means available. Ishiguro’s novels are written in an expanded humanistic tradition. They are stories dealing with human relationship. They are narratives centering on the working of consciousness and the unconsciousness of the human mind. Ishiguro is concerned with reworking of the past from a late twentieth century perspective. The purpose of this study is to trace the postmodern aspects in The Remains of The Day through the life and character of Stevens and his relationships with the people that he has lived with. Stevens struggles to come to term with his present through telling stories and anecdotes of his past life. The novel depicts the role that memories can play in reconstructing the past events so that the present can be meaningful in some way from a postmodern standpoint. As a postwar British individual, the protagonist of the novel tries to practice suppression over his emotions at the personal level as well as the professional level to construct a new identity. Stevens appears torn between memories of the past and the representation of the present. He is suffering from an identity crisis and striving to create a meaningful present for himself. As a postmodern man, Stevens has to struggle at different levels. He is leading a life riddled with inconsistencies and contradictions. He can’t feel at home with the surrounding world as he is always busy trying to achieve some perfection that is not attainable in a world riddled with conflicts and struggle.

"Deti iz bezdnõ" Pavla Tshuhraja" / Lina Kornejeva

Index Scriptorium Estoniae

Kornejeva, Lina

2003-01-01

Pavel Tshuhrai USA televisiooni miniseriaalile tehtud dokumentaalfilm holokaustist "Sügaviku lapsed" ("Children from the Abyss"/"Deti iz bezdnõ"), mille tellis Steven Spielbergi asutatud fond "Shoa"

Uncommon vancomycin: induced side effects

Directory of Open Access Journals (Sweden)

Rocha Jaime Luís Lopes

2002-01-01

Full Text Available Vancomycin has been used with increased frequency during the past 15 years and the most common toxicity with this drug is the "red man syndrome". Other adverse effects include neutropenia, fever, phlebitis, nephrotoxicity, ototoxicity, thrombocytopenia, interstitial nephritis, lacrimation, linear IgA bullous dermatosis, necrotizing cutaneous vasculitis and toxic epidermal necrolysis. Only two cases of vancomycin-induced Stevens-Johnson syndrome and one case of pancytopenia have been reported in the medical literature. The treatment for both situations is based on cessation of the vancomycin therapy; in cases of Stevens-Johnson syndrome, antihistamine and/or steroid agents can be used. This article reports a case of pancytopenia and a case of erythema major associated with neutropenia.

77 FR 67020 - Performance Review Board Appointments

Science.gov (United States)

2012-11-08

..., Tommy Beck, Richard Belin, Alletta Berrigan, Michael Black, Michael Black, Steven Blanchard, Mary Josie..., Robert Reidenbach, Dennis Reynolds, Michael Rice, Bryan Roberson, Edwin Rountree, Carl Russ, David...

78 FR 29612 - Prevailing Rate Systems; Redefinition of the Minneapolis-St. Paul, MN, and Southwestern Wisconsin...

Science.gov (United States)

2013-05-21

... Renville Rice Sherburne Sibley Stearns Steele Stevens Swift Todd Traverse Wabasha Wadena Waseca Watonwan... Langlade Lincoln Marathon Marinette Menominee Oneida Pepin Portage Price Richland Rusk Shawano Taylor...

Think Tek Learning Lab, Phase I

Data.gov (United States)

National Aeronautics and Space Administration — Steven Winter Associates, Inc. (SWA) proposes to develop a nation-wide informal technology education program that integrates math, science, engineering and...

Multiple Landslide-Hazard Scenarios Modeled for the Oakland-Berkeley Area, Northern California

Science.gov (United States)

Pike, Richard J.; Graymer, Russell W.

2008-01-01

With the exception of Los Angeles, perhaps no urban area in the United States is more at risk from landsliding, triggered by either precipitation or earthquake, than the San Francisco Bay region of northern California. By January each year, seasonal winter storms usually bring moisture levels of San Francisco Bay region hillsides to the point of saturation, after which additional heavy rainfall may induce landslides of various types and levels of severity. In addition, movement at any time along one of several active faults in the area may generate an earthquake large enough to trigger landslides. The danger to life and property rises each year as local populations continue to expand and more hillsides are graded for development of residential housing and its supporting infrastructure. The chapters in the text consist of: *Introduction by Russell W. Graymer *Chapter 1 Rainfall Thresholds for Landslide Activity, San Francisco Bay Region, Northern California by Raymond C. Wilson *Chapter 2 Susceptibility to Deep-Seated Landsliding Modeled for the Oakland-Berkeley Area, Northern California by Richard J. Pike and Steven Sobieszczyk *Chapter 3 Susceptibility to Shallow Landsliding Modeled for the Oakland-Berkeley Area, Northern California by Kevin M. Schmidt and Steven Sobieszczyk *Chapter 4 Landslide Hazard Modeled for the Cities of Oakland, Piedmont, and Berkeley, Northern California, from a M=7.1 Scenario Earthquake on the Hayward Fault Zone by Scott B. Miles and David K. Keefer *Chapter 5 Synthesis of Landslide-Hazard Scenarios Modeled for the Oakland-Berkeley Area, Northern California by Richard J. Pike The plates consist of: *Plate 1 Susceptibility to Deep-Seated Landsliding Modeled for the Oakland-Berkeley Area, Northern California by Richard J. Pike, Russell W. Graymer, Sebastian Roberts, Naomi B. Kalman, and Steven Sobieszczyk *Plate 2 Susceptibility to Shallow Landsliding Modeled for the Oakland-Berkeley Area, Northern California by Kevin M. Schmidt and Steven

Indiana protiv KGB / Anna Fedina, Pjotr Obraztsov

Index Scriptorium Estoniae

Fedina, Anna

2008-01-01

Steven Spielbergi neljas Indiana Jones'i film Harrison Fordiga nimiosas "Indiana Jones ja kristallpealuu kuningriik" ("Indiana Jones and the Kingdom of the Crystal Skull") : Ameerika Ühendriigid 2008

Superkangelase neljas tulemine / Signe Sillasoo

Index Scriptorium Estoniae

Sillasoo, Signe

2008-01-01

Steven Spielbergi neljas Indiana Jones'i film Harrison Fordiga nimiosas "Indiana Jones ja kristallpealuu kuningriik" ("Indiana Jones and the Kingdom of the Crystal Skull") : Ameerika Ühendriigid 2008

Sangari naasmine / Jaanus Noormets

Index Scriptorium Estoniae

Noormets, Jaanus

2008-01-01

Steven Spielbergi neljas Indiana Jones'i film Harrison Fordiga nimiosas "Indiana Jones ja kristallpealuu kuningriik" ("Indiana Jones and the Kingdom of the Crystal Skull") : Ameerika Ühendriigid 2008

Vana ja tuttav, aga liiga turvaline / Alar Niineväli

Index Scriptorium Estoniae

Niineväli, Alar

2008-01-01

Steven Spielbergi neljas Indiana Jones'i film Harrison Fordiga nimiosas "Indiana Jones ja kristallpealuu kuningriik" ("Indiana Jones and the Kingdom of the Crystal Skull") : Ameerika Ühendriigid 2008

Nad avantjuristom godõ ne vlastnõ / Boris Tuch

Index Scriptorium Estoniae

Tuch, Boris, 1946-

2008-01-01

Steven Spielbergi neljas Indiana Jones'i film Harrison Fordiga nimiosas "Indiana Jones ja kristallpealuu kuningriik" ("Indiana Jones and the Kingdom of the Crystal Skull") : Ameerika Ühendriigid 2008

X-Files kohtub Indy'ga / Rivo Sarapik

Index Scriptorium Estoniae

Sarapik, Rivo, 1981-

2008-01-01

Steven Spielbergi neljas Indiana Jones'i film Harrison Fordiga nimiosas "Indiana Jones ja kristallpealuu kuningriik" ("Indiana Jones and the Kingdom of the Crystal Skull") : Ameerika Ühendriigid 2008

Koltunud Indiana Jones / Kutt Kommel

Index Scriptorium Estoniae

Kommel, Kutt

2008-01-01

Steven Spielbergi neljas Indiana Jones'i film Harrison Fordiga nimiosas "Indiana Jones ja kristallpealuu kuningriik" ("Indiana Jones and the Kingdom of the Crystal Skull") : Ameerika Ühendriigid 2008

Indiana Jones ja kristallpealuu kuningriik / Jaanus Noormets

Index Scriptorium Estoniae

Noormets, Jaanus

2008-01-01

Steven Spielbergi neljas Indiana Jones'i film Harrison Fordiga nimiosas "Indiana Jones ja kristallpealuu kuningriik" ("Indiana Jones and the Kingdom of the Crystal Skull") : Ameerika Ühendriigid 2008

Mis te Indyga teete?

Index Scriptorium Estoniae

2008-01-01

Steven Spielbergi neljas Indiana Jones'i film Harrison Fordiga nimiosas "Indiana Jones ja kristallpealuu kuningriik" ("Indiana Jones and the Kingdom of the Crystal Skull") : Ameerika Ühendriigid 2008

"Salatoimikud" Indiana Jonesi moodi / Inna-Katrin Hein

Index Scriptorium Estoniae

Hein, Inna-Katrin

2008-01-01

Steven Spielbergi neljas Indiana Jones'i film Harrison Fordiga nimiosas "Indiana Jones ja kristallpealuu kuningriik" ("Indiana Jones and the Kingdom of the Crystal Skull") : Ameerika Ühendriigid 2008

Väike psühhoanalüüs Indiana Jonesile / Aarne Ruben

Index Scriptorium Estoniae

Ruben, Aarne, 1971-

2008-01-01

Steven Spielbergi neljas Indiana Jones'i film Harrison Fordiga nimiosas "Indiana Jones ja kristallpealuu kuningriik" ("Indiana Jones and the Kingdom of the Crystal Skull") : Ameerika Ühendriigid 2008

Pärt: Berliner Messe / Rob Cowan

Index Scriptorium Estoniae

Cowan, Rob

1998-01-01

Uuest heliplaadist "Pärt: Berliner Messe. The Beatitudes. Annum per Annum. Magnificat. Seven Magnificat Antiphons. De profundis. Polyphony / Steven Layton with Andrew Lucas" Hyperion CDA66960 (74 minutes:DDD)

Nine Steps to More Effective Parenting

Science.gov (United States)

... your own well-being, which is another important value to model for your children. Reviewed by: Steven Dowshen, ... Your Child Tolerance Teaching Your Child Self-Control Disciplining Your Child ...

77 FR 20382 - Whitestone Power and Communications; Notice of Preliminary Permit Application Accepted for Filing...

Science.gov (United States)

2012-04-04

... (FPA), proposing to study the feasibility of the Microturbine Hydrokinetic River-In-Stream Energy.... Applicant Contact: Mr. Steven M. Selvaggio, Whitestone Power and Communications, P.O. Box 1630, Delta...

76 FR 10593 - Ocean Transportation Intermediary License Applicants

Science.gov (United States)

2011-02-25

... Individual), Steven L. Leturno, Director, Application Type: QI Change. Combined Freight System, Inc. (NVO...), 148-08 Guy R. Brewer Blvd., Jamaica, NY 11434, Officers: Wei Hu, Vice President, (Qualifying...

76 FR 66856 - Fisheries of the Northeastern United States; Northeast Skate Complex Fishery; Secretarial...

Science.gov (United States)

2011-10-28

... still protecting skates from overfishing. DATES: Effective November 28, 2011, through April 30, 2012... conservation concerns (e.g., overfishing), and Magnuson-Stevens Act emergency actions have been used in the...

Arvuti poseerib / Steve Farrar

Index Scriptorium Estoniae

Farrar, Steve

1999-01-01

Rootsi disainer Steven Stahlberg on modelliagentuurile "Elite" loonud esimese virtuaalmodelli Webbie Tookay. Virtuaalmodellide tulevikust. Kommenteerivad "Elite Illusion 2K" direktor R. Bellino, briti moefotograaf N. Knight, moeajaloolane C. McDowell.

Kunstitarbimisorgia kunstlikult põhjamaises suvitusrajoonis / Mari Sobolev

Index Scriptorium Estoniae

Sobolev, Mari, 1968-

2004-01-01

Jaan Toomiku ja Paul Rodgersi organiseeritud tegevuskunsti festivalist "Viinistu 2004", kavas performance'id, installatsioonid, video, näitused. Pikemalt Steven Coheni, Elu, Neeme Külma, Minna Hindi, Erik Alalooga esinemisest

Steven Vogel and His Theory of Comparative Biomechanics

Indian Academy of Sciences (India)

IAS Admin

on the development, physiology, and disease of living things. I have a ... Vogel was a prolific writer of popular science articles and books. .... is a new line of thinking here. Even though the .... to make it suitable to teach engineering stu- dents?

Stevens –Johnson syndrome due to nevirapine | Namayanja ...

African Journals Online (AJOL)

African Health Sciences. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 5, No 4 (2005) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here ...

Commission : Paksas violated oath of office / Steven Paulikas

Index Scriptorium Estoniae

Paulikas, Steven

2003-01-01

Leedu presidendi ümber puhkenud skandaali uuriv Seimi erikomisjon leidis, et president Rolandas Paksas oli ja on oma sidemete tõttu haavatav ning see kujutab ohtu riigi julgeolekule. Lisa: Commission conclusions

MEP : Political parties funded by bribes / Steven Paulikas

Index Scriptorium Estoniae

Paulikas, Steven

2004-01-01

Leedu Sotsiaaldemokraatliku Partei liikme, Euroopa Parlamendi saadiku Aloyzas Sakalase hinnangul finantseeritakse Leedu parteisid altkäemaksudest ja korruptsioonis süüdistatavad parlamendiliikmed tegutsesid oma parteide nimel

75 FR 9531 - Magnuson-Stevens Act Provisions; Correction

Science.gov (United States)

2010-03-03

... for comment are not required pursuant to 5 U.S.C. 553, or any other law, the analytical requirements..., rod and reel, spear, trap, slurp gun, hand harvest. C. Charter fishery C. Bandit gear, buoy gear..., gillnet, hand harvest, seine, slurp gun, trap, spear, rod and reel, hook and line. 12. Recreational...

Vilnius mayor dragged into corruption scandal / Steven Paulikas

Index Scriptorium Estoniae

Paulikas, Steven

2004-01-01

Vilniuse linnapea Arturas Zuokase suhtes on algatatud kriminaalmenetlus, süüdistuseks koos korporatsiooni Rubicon juhi Andrius Janukonisega altkäemaksu pakkumine linnavolikogu liikmele Vilmantas Dremale linnapea valimiste eel

Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis ...

African Journals Online (AJOL)

illness until research found that morbidity can result from a ... for the widespread keratinocyte necrosis in SJS and TEN.⁷. Granulysin is the most ... Clinical presentation. SJS and ... Burns Intensive Care Unit may be one of the most important.

Report: Paksas scandal raises privacy concerns / Steven Paulikas

Index Scriptorium Estoniae

Paulikas, Steven

2004-01-01

Inimõiguste ekspertide uuring näitab, et nii Leedu presidendi Rolandas Paksase administratsiooni töötajad, presidendi tegevuse uurijad kui ka Leedu ajakirjandus rikkusid mitmeid inimõigusi, eelkõige aga õigust privaatsusele

Zuokas accuses paper of journalistic blackmail / Steven Paulikas

Index Scriptorium Estoniae

Paulikas, Steven

2004-01-01

Vilniuse linnapea, Leedu Liberaaltsentristliku Liidu liider Arturas Zuokas süüdistab ajalehe Respublika peatoimetajat Vitas Tomkust väljapressimises. Ajaleht on avaldanud mitu Zuokase jaoks ebameeldivat artiklit, milles räägitakse tema väidetavatest sidemetest vastuolulise mainega ettevõtjatega

76 FR 48143 - Certain Hot-Rolled Carbon Steel Flat Products From the People's Republic of China: Preliminary...

Science.gov (United States)

2011-08-08

..., 75 FR 81565 (December 28, 2010). \\3\\ Certain Oil Country Tubular Goods from the People's Republic of..., from Steven Hampton, International Trade Analyst, ``Certain Hot-Rolled Carbon Steel Flat Products from...

Kolm õde Eestist Londoni laval / Andres Laasik

Index Scriptorium Estoniae

Laasik, Andres, 1960-2016

1999-01-01

Inglise näitleja Steven Dykesi näidend "Kolonistid" Londoni Bridge Lane Theatre laval. Näidend on inspireeritud A. Tshehhovi "Kolmest õest" ja tegevus toimub Eestis, tegelased on siinsed venelased

DATA MINING THE GALAXY ZOO MERGERS

Data.gov (United States)

National Aeronautics and Space Administration — DATA MINING THE GALAXY ZOO MERGERS STEVEN BAEHR, ARUN VEDACHALAM, KIRK BORNE, AND DANIEL SPONSELLER Abstract. Collisions between pairs of galaxies usually end in the...

Siim Nestor. Viis jõululaulu / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2007-01-01

Lauludest: Sufjan Stevens "Come On! Let's Boogey to the Elf dance", Frank Sinatra "Whatever Happened to Christmas?", Vaiko Eplik ja Eliit "Kas usud sinagi", Panda Bear "Bros", Prince "Another Lonely Christmas"

75 FR 47274 - Caribbean Fishery Management Council; Public Meeting

Science.gov (United States)

2010-08-05

... Drive, St. Thomas, U.S. Virgin Islands. FOR FURTHER INFORMATION CONTACT: Caribbean Fishery Management... contained in this agenda may come before this group for discussion, in accordance with the Magnuson- Stevens...

77 FR 26048 - Notice of Permit Applications Received Under the Antarctic Conservation Act of 1978 (Pub. L. 95-541)

Science.gov (United States)

2012-05-02

.... Applicant: Steven D. Emslie, Department of Biology and Marine Biology, University of North Carolina... bone concentrations, rich vegetation). These sites will be sampled by placing a test pit, no more than...

50 CFR 665.12 - Definitions.

Science.gov (United States)

2010-10-01

... intended to enter commerce or enter commerce through sale, barter, or trade. All lobster fishing in... under the Magnuson-Stevens Act. Vessel monitoring system unit (VMS unit) means the hardware and software...

75 FR 46899 - Agency Information Collection Activities: Proposed Collection; Comment Request-In-Depth Case...

Science.gov (United States)

2010-08-04

... techniques or other forms of information technology. Comments may be sent to: Steven Carlson, Director... States will receive remuneration of $75,000 to offset the costs of participating in the study. Interview...

Snow Show Lapimaal / Karin Hallas-Murula

Index Scriptorium Estoniae

Hallas-Murula, Karin, 1957-

2003-01-01

2004. a. Rovaniemis läbiviidavast rahvusvahelisest jää- ja lumearhitektuuri üritusest, kuraator Lance Fung. Steven Holli jääplokkidest kuup - projekti pilootehitis. Osalevate arhitektide ja kunstnike osaline loetelu

77 FR 75589 - Prevailing Rate Systems; Redefinition of the Minneapolis-St. Paul, MN, and Southwestern Wisconsin...

Science.gov (United States)

2012-12-21

... Nicollet Olmsted Pope Redwood Renville Rice Sherburne Sibley Stearns Steele Stevens Swift Todd Traverse... Shawano Taylor Vernon Vilas Waupaca Wood * * * * * [FR Doc. 2012-30805 Filed 12-20-12; 8:45 am] BILLING...

75 FR 7570 - Federal Advisory Committee; Military Leadership Diversity Commission (MLDC); Meeting Cancellation

Science.gov (United States)

2010-02-22

... Chief Steven A. Hady, Designated Federal Officer, MLDC, at (703) 602-0838, 1851 South Bell Street, Suite 532, Arlington, VA, E-mail [email protected] . Dated: February 16, 2010. Mitchell S. Bryman...

STS-93: Crew Watches the Installation of Chandra's Solar Panel in the VPF

Science.gov (United States)

1999-01-01

The crew (Commander Eileen M. Collins, Pilot Jeffrey S. Ashby, Mission Specialists Steven A. Hawley, Catherine G. Coleman, and Michael Tognini) are dressed in cleanroom suits while overseeing the solar panel installation.

1001 filmi nagu punane rätik härjale / Tiit Tuumalu

Index Scriptorium Estoniae

Tuumalu, Tiit, 1971-

2004-01-01

Inglise originaalist tõlgitud ligi 1000-leheküljeline teatmeteos "1001 filmi, mida elu jooksul peab nägema" (toimetaja Steven Jay Schneider). Artiklile lisatud filmikriitikute Jaan Ruusi ja Lauri Kärgi kommentaarid

Hollywood tormas poliitilisse võitlustulle / Andres Laasik

Index Scriptorium Estoniae

Laasik, Andres, 1960-2016

2006-01-01

Poliitiliselt tundlikud Hollywoodi uued mängufilmid - George Clooney "Head õhtut ja õnn kaasa" ("Good Night, and Good Luck"), Steven Spielbergi "München" ("Munich") ja Ang Lee "Brokebacki mägi" ("Brokeback Mountain")

The team from AB Department that brought the accelerator chain to a new intensity record on 2 October.

CERN Multimedia

Patrice Loiez

2004-01-01

From left to right, sitting: Elena Shaposhnikova, Thomas Bohl, Gianluigi Arduini, and standing: Klaus Hanke, Trevor Linnecar, Rende Steerenberg, Michel Chanel, Roland Garoby, Elias Métral. Not pictured: Steven Hancock and Bernard Vandorpe.

DVD. Alar Niineväli hoiatab. "Hüppaja" / Alar Niineväli

Index Scriptorium Estoniae

Niineväli, Alar

2008-01-01

Ulmeline seiklusfilm "Hüppaja" ("Jumper") Steven Gould'i teoste põhjal : stsenaristid David Goyer, Simon Kinberg, Jim Uhls : režissöör Doug Liman : peaosas Hayden Christensen : Ameerika Ühendriigid 2008

On alles hüpe! / Laurence Lumiere

Index Scriptorium Estoniae

Lumiere, Laurence

2008-01-01

Ulmeline seiklusfilm "Hüppaja" ("Jumper") Steven Gould'i teoste põhjal : stsenaristid David Goyer, Simon Kinberg, Jim Uhls : režissöör Doug Liman : peaosas Hayden Christensen : Ameerika Ühendriigid 2008

Vastukarva pai / Mari Laaniste

Index Scriptorium Estoniae

Laaniste, Mari, 1977-

2007-01-01

Mängufilm "Karusnahk: Diane Arbuse kujutletav portree" ("Fur: An Imaginary Portrait of Diane Arbuse") : stsenarist Erin Cressida Wilson : režissöör Steven Shainberg : nimiosas Nicole Kidman : Ameerika Ühendriigid 2006

Kolm tundi päevas jõusaalis ja dieet : nii voolis Harrison Ford end taas Indiana Jonesiks / Triin Tael

Index Scriptorium Estoniae

Tael, Triin

2008-01-01

Steven Spielbergi neljas Indiana Jones'i film Harrison Fordiga nimiosas "Indiana Jones ja kristallpealuu kuningriik" ("Indiana Jones and the Kingdom of the Crystal Skull") : Ameerika Ühendriigid 2008. Indiana Jonesi tähestik

Appropriate tools and methods for tropical microepidemiology: a ...

African Journals Online (AJOL)

Appropriate tools and methods for tropical microepidemiology: a case-study of malaria clustering in Ethiopia. Tedros A Ghebreyesus, Peter Byass, Karen H Witten, Asfaw Getachew, Mitiku Haile, Mekonnen Yohannes, Steven W Lindsay ...

Prevalence, risk factors and risk perception of tuberculosis infection ...

African Journals Online (AJOL)

Prevalence, risk factors and risk perception of tuberculosis infection among medical students and healthcare workers in Johannesburg, South Africa. A van Rie, K McCarthy, L Scott, A Dow, WDF Venter, WS Stevens ...

Tooth Problems

Science.gov (United States)

... may have an infection such as TRENCH MOUTH, GINGIVITIS or PERIODONTITIS. A rare drug reaction, STEVENS-JOHNSON ... Control Family Health Infants and Toddlers Kids and Teens Pregnancy and Childbirth Women Men Seniors Your Health ...

Eros / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2006-01-01

Kolmest iseseisvast armastusloost koosnev episoodfilm "Eros" : režissöörid Wong Kar-Wai ("Käsi"), Steven Soderbergh ("Tasakaal" / "Equilibrium"), Michelangelo Antonioni ("Asjade ohtlik käik") : Hongkong - Hiina - USA - Prantsuse - Itaalia 2004

Kaks musketäri. 20 aastat hiljem / Tristan Priimägi

Index Scriptorium Estoniae

Priimägi, Tristan, 1976-

2007-01-01

Tristan Priimägi kohtumisest Londoni klubis Hard Rock Cafe ameerika rockansambli Aerosmith liikmetega, intervjuu Steven Tyleriga. Heliplaatidest "Aerosmith", "Toys in the Attic", Run D.M.C & Aerosmith "Walk This Way", Get a Grip"

75 FR 13653 - Qualification of Drivers; Exemption Applications; Vision

Science.gov (United States)

2010-03-22

... D. Bennett, Johnny W. Bradford Sr., Levi A. Brown, Charlie F. Cook, Clifford H. Dovel, Arthur L..., Steven L. Valley, Thomas E. Voyles, Jr., Darel G. Wagner, Bernard J. Wood. These exemptions are extended...

First Aid: Rashes

Science.gov (United States)

... Development Infections Diseases & Conditions Pregnancy & Baby Nutrition & Fitness Emotions & Behavior School & Family Life First Aid & Safety Doctors & ... avoid sunburn . If your child tends to get eczema flare-ups, avoid harsh soaps. Reviewed by: Steven ...

76 FR 42508 - Effective Date for Swap Regulation

Science.gov (United States)

2011-07-19

... the General Counsel, or Steven Kane, Consultant, 202-418-5911, [email protected] , Office of the Chief...., letter dated July 1, 2011, from R. Michael Sweeney, Jr., Hunton & Williams, on behalf of the Working...

75 FR 47810 - Granting of Request for Early Termination of the Waiting Period Under the Premerger Notification...

Science.gov (United States)

2010-08-09

...-Scott Rodino Antitrust Improvements Act of 1976, requires persons contemplating certain mergers or... status Party name 30-JUN-10 20100840 G Li & Fung Limited. G Steven Kahn. G The Max Leather Group, Inc. G...

50 CFR 654.7 - Prohibitions.

Science.gov (United States)

2010-10-01

..., search, seizure, or disposition of seized property in connection with enforcement of the Magnuson-Stevens..., due to the Deepwater Horizon oil spill. [60 FR 13919, Mar. 15, 1995, as amended at 67 FR 47469, July...

Tõotatud maa ameerika lastekirjanduses ehk kuidas kasvatada lapsest diktaator / David Ilmar Beecher

Index Scriptorium Estoniae

Beecher, David Ilmar

2015-01-01

Lastekirjandusest teadusliku allikana ning Maurice Sendaci lasteraamatust "Where the wild things are" (1964) ja Steven Kelloggi lasteraamatust "The island of the Skog" (1976). Tekst põhineb "Õnnekonverentsi" ettekandel, mis peeti 3. mail 2011. aastal

Berlinale 2003 : "Lenin" - poeg lavastab ema jaoks Saksa DV edasikestmise / Jaak Lõhmus

Index Scriptorium Estoniae

Lõhmus, Jaak

2003-01-01

Festivalist, mis toimub loosungi all "Towards tolerance" ja võistluskava filmidest : briti režissööri Michael Winterbottomi "Siin maailmas", sakslase Wolfgang Beckeri absurdikomöödia "Jumalaga, Lenin!" ning Steven Soderberghi "Solaris"

Placebo Effect

Science.gov (United States)

... C. Spencer, MD Steven Karceski, MD The placebo effect Joseph H. Friedman, MD Richard Dubinsky, MD WHAT ... placebo: a “dummy” medication that should have no effect on the condition. Placebos are not only drugs. ...

Nostalgiline nagu soe tekk / Lauri Kaare

Index Scriptorium Estoniae

Kaare, Lauri

2008-01-01

22 mail esilinastub Steven Spielbergi järjekordne Indiana Jones'i film, kaasstsenaristiks ja produtsendiks George Lucas ja Harrison Fordiga nimiosas "Indiana Jones ja kristallpealuu kuningriik" ("Indiana Jones and the Kingdom of the Crystal Skull")

Indiana Dzhons vozvrashtshajetsja / Melor Sturua

Index Scriptorium Estoniae

Sturua, Melor

2008-01-01

22 mail esilinastub Steven Spielbergi järjekordne Indiana Jones'i film, kaasstsenaristiks ja produtsendiks George Lucas ja Harrison Fordiga nimiosas "Indiana Jones ja kristallpealuu kuningriik" ("Indiana Jones and the Kingdom of the Crystal Skull")

Mechanisms of neuro- and cytotoxicity of local anesthetics and their adjuvants

NARCIS (Netherlands)

Stevens, M.F.

2012-01-01

Plaatselijke verdovingsmiddelen zetten een mechanisme in gang waarbij zenuwcellen zichzelf vernietigen. Dit kan leiden tot zenuwschade. Stevens wilde achterhalen hoe die zenuwschade ontstaat. Hij toont aan dat alle gangbare plaatselijke verdovingsmiddelen een soort zelfmoordmechanisme van

Rahu, ainult rahu / Karin Bachmann

Index Scriptorium Estoniae

Bachmann, Karin, 1976-

2013-01-01

Eesti Kunstiakadeemia X Urbanistika ja linnamaastike päevad "Between Architecture of War and Military Urbanism" ("Sõjaarhitektuuri ja militaarurbanistika vahel") 25.-28. aprillil 2013. a. Telliskivi Loomelinnakus Tallinnas. Konverentsi peaesinejad Stephen Graham ja Steven Flusty

75 FR 42790 - Exelon Generation Company, LLC; Clinton Power Station; Environmental Assessment and Finding of No...

Science.gov (United States)

2010-07-22

... to essential fish habitat covered by the Magnuson-Stevens Act are expected. There are no impacts to... Elimination System permit are needed. No effects on the aquatic or terrestrial habitat in the vicinity or the...

Appraisal of the surficial aquifers in the Pomme de Terre and Chippewa River Valleys, western Minnesota

Science.gov (United States)

Soukup, W.G.; Gillies, D.C.; Myette, C.F.

1984-01-01

The surf icial sands in the Pomme de Terre and Chippewa River valleys in Grant, Pope, Stevens, and Swift Counties have been studied to determine the occurrence, availability, and quality of ground water in these aquifers.

Problem That Piles Up: When Hoarding Is a Disorder

Science.gov (United States)

... how to let things go.” “We can find support groups for people who hoard.” “We can ask the ... of neural activity during response inhibition. Tolin DF, Witt ST, Stevens MC. Psychiatry Res . ...

Portal Hypertension

Science.gov (United States)

... Overview of Gallbladder Cancer Additional Content Medical News Portal Hypertension By Steven K. Herrine, MD, Professor of Medicine, ... Liver Hepatic Encephalopathy Jaundice in Adults Liver Failure Portal Hypertension Portal hypertension is abnormally high blood pressure in ...

Aasta parimad ja halvimad juhid: vaprad hoidsid kurssi, paar tähte kustus

Index Scriptorium Estoniae

2005-01-01

USA majandusajakirja BusinessWeek poolt läbi viidud uuringu andmetel olid 2004. aasta parimad juhid Jeffrey Immelt (General Electric) ja Steven Reinemund (PepsiCo) ning halvimad juhid Raymond Gilmartin (Merck) ja Michael Eisner (Walt Disney)

six six six paradox : [luuletused] / Triin Tasuja

Index Scriptorium Estoniae

Tasuja, Triin

2008-01-01

Sisu: six six six paradox ; cat stevens ; "vahel tundub, et mu ümber..." ; sääse ; Salaalaealised ; kolkalapsed ; longin mööda lumiseid tänavaid ; punkrock dekadents ; "Igast kirjaneitsist..." ; "mina olengi see saikochick..."

Studies in Interior Design

Science.gov (United States)

Environ Planning Design, 1970

1970-01-01

Floor plans and photographs illustrate a description of the Samuel C. Williams Library at Stevens Institute of Technology, Hoboken, N.J. The unusual interior design allows students to take full advantage of the library's resources. (JW)

75 FR 27623 - Qualification of Drivers; Exemption Applications; Vision

Science.gov (United States)

2010-05-17

.... Askin, Paul J. Bannon, Ernie E. Black, Ronnie F. Bowman, Gary O. Brady, Stephen H. Goldcamp, Steven F. Grass, Wai F. King, Dennis E. Krone, Richard J. McKenzie, Jr., Christopher J. Meerten, Craig W. Miller...

Multiple Sclerosis and Vitamin D

Science.gov (United States)

... Editors David C. Spencer, MD Steven Karceski, MD Multiple sclerosis and vitamin D Andrew J. Solomon, MD WHAT ... caused by improper immune responses (autoimmune diseases), including multiple sclerosis (MS). A recent Patient Page in Neurology provided ...

78 FR 26107 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

Science.gov (United States)

2013-05-03

... Christopher W. Bailey (OH), Kent S. Bills (IN), Bobby B. Brown (VA), Maryland A. Chandler (KY), Ronald D. Clark (AR), Larry L. Eberly (PA), Steven J. Fessler (IL), Michael R. Fisher (IA), Mark A. Krause (PA...

Genetics Home Reference: PURA syndrome

Science.gov (United States)

... TJ, Vreeburg M, Rouhl RPW, Stevens SJC, Stegmann APA, Schieving J, Pfundt R, van Dijk K, Smeets ... article on PubMed Central More from Genetics Home Reference Bulletins Genetics Home Reference Celebrates Its 15th Anniversary ...

78 FR 52123 - Atlantic Highly Migratory Species; 2006 Consolidated Highly Migratory Species Fishery Management...

Science.gov (United States)

2013-08-22

... Management Act (Magnuson-Stevens Act) and the Atlantic Tunas Convention Act (ATCA). Under the Magnuson... August 28, 2013, 6 San Antonio, TX.... Hilton Palacio Del Rio, 200 S. with the Gulf of Mexico Fishery p.m...

Sõda ilma sentimentaalsuseta / Mari Laaniste

Index Scriptorium Estoniae

Laaniste, Mari, 1977-

2006-01-01

10-osaline sõjaseriaal "Relvavennad" ("Band of Brothers") ajalooprofessor Stephen Ambrose'i raamatu järgi : produtsendid Tom Hanks, Steven Spielberg : režissöörid Tom Hanks, David Frenkel jt. : Ameerika Ühendriigid - Suurbritannia 2001

Sõjaromantikud said seriaali / Toomas Hiio

Index Scriptorium Estoniae

Hiio, Toomas, 1965-

2006-01-01

10-osaline sõjaseriaal "Relvavennad" ("Band of Brothers") ajalooprofessor Stephen Ambrose'i raamatu järgi : produtsendid Tom Hanks, Steven Spielberg : režissöörid Tom Hanks, David Frenkel jt. : Ameerika Ühendriigid - Suurbritannia 2001

Folk, akustiline selline, on hambus Tristan Priimäel / Tristan Priimägi

Index Scriptorium Estoniae

Priimägi, Tristan, 1976-

2004-01-01

Heliplaatidest: Iron & Wine "Our Endless Numbered Days", Sufjan Stevens "Seven Swans", Joanna Newsom "The Milk-Eyed Mender", Nick Drake "Made to Love Magic", Kings Of Convenience "Riot On an Empty Street", White Magic "Through the Sun Door"

75 FR 58429 - Notice of Inventory Completion: Northwest Museum of Arts & Culture, Spokane, WA

Science.gov (United States)

2010-09-24

... 31 (45-ST-31), one-quarter of a mile above the Gifford-Inchelium ferry landing, in Stevens County, WA... deformation, and structural remnants found at the sites (pit and earth ovens), it is determined that the human...

Poison Ivy

Science.gov (United States)

... been out exploring the woods, you might want to give your pet a shower, too! Reviewed by: Steven Dowshen, MD Date reviewed: February ... Visit the Nemours Web site. Note: All information on KidsHealth® is for ...

75 FR 38603 - Qualification of Drivers; Exemption Renewals; Vision

Science.gov (United States)

2010-07-02

... James C. Askin, Paul J. Bannon, Ernie E. Black, Ronnie F. Bowman, Gary O. Brady, Stephen H. Goldcamp, Steven F. Grass, Wai F. King, Dennis E. Krone, Richard J. McKenzie, Jr., Christopher J. Meerten, Craig W...

Mild Cognitive Impairment and Progession to Dementia: New Findings

Science.gov (United States)

... David C. Spencer, MD Steven Karceski, MD Mild cognitive impairment and progression to dementia New findings John C.S. ... exami- nations showed that 534 persons had mild cognitive impairment, or MCI (see About MCI, following sec- tion). ...

75 FR 27620 - Qualification of Drivers; Exemption Renewals; Vision

Science.gov (United States)

2010-05-17

..., Sr., Levi A. Brown, Charlie F. Cook, Clifford H. Dovel, Arthur L. Fields, John W. Forgy, Glenn E. Gee..., Monte L. Purciful, Luis F. Saavedra, Earl W. Sheets, Robert V. Sloan, Steven L. Valley, Thomas E. Voyles...

77 FR 6776 - Agency Information Collection Activities: Proposed Collection; Comment Request-National School...

Science.gov (United States)

2012-02-09

..., mechanical, or other technological collection techniques or other forms of information technology. Comments... be directed to Steven Carlson at 703-305-2017. SUPPLEMENTARY INFORMATION: Title: National School... DEPARTMENT OF AGRICULTURE Food and Nutrition Service Agency Information Collection Activities...

75 FR 38597 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

Science.gov (United States)

2010-07-02

..., Duane C. Jackson, John J. Long, Jerry A. McMurdy, Steven L. Miller, Joe E. Montoya, Jonathan A. Morisoli.... Tomasik, Leonard D. Tournear, Booker T. Ware and Joseph H. Watkins, from the ITDM standard in 49 CFR 391...

Ecological periodic tables for nekton and benthic macrofaunal community usage of estuarine habitats Slides

Science.gov (United States)

Ecological periodic tables for nekton and benthic macrofaunal community usage of estuarine habitats Steven P. Ferraro, U.S. Environmental Protection Agency, Newport, OR Background/Questions/Methods The chemical periodic table, the Linnaean system of classification, and the Her...

At Fermilab, the race is on for the "God Particle"

CERN Multimedia

Overbye, Dennis

2007-01-01

Dr Steven Weinberg, in 1977, heard a rumor that collisions were spitting out weird triplets of particles known as muons, which are sor of fat electrons. He tried to concoct a theory to explain the trimuons. (1 page)

Three Women Scientists and Their Role in the History of Genetics.

Science.gov (United States)

Venville, Grady; Milne, Catherine

1999-01-01

Draws on an array of historical documents to delve into the history of genetics and the lives and scientific accomplishments of female geneticists that include Nettie Stevens, Rosalind Franklin, and Barbara McClintock. (Contains 20 references.) (Author/WRM)

75 FR 3434 - Fisheries of the Northeastern United States; Northeast Skate Complex Fishery; Amendment 3

Science.gov (United States)

2010-01-21

...NMFS proposes regulations to implement measures in Amendment 3 to the Northeast Skate Complex Fishery Management Plan (Skate FMP). Amendment 3 was developed by the New England Fishery Management Council (Council) to rebuild overfished skate stocks and implement annual catch limits (ACLs) and accountability measures (AMs) consistent with the requirements of the reauthorized Magnuson-Stevens Fishery Conservation and Management Act (Magnuson-Stevens Act). Amendment 3 would implement a rebuilding plan for smooth skate and establish an ACL and annual catch target (ACT) for the skate complex, total allowable landings (TAL) for the skate wing and bait fisheries, seasonal quotas for the bait fishery, reduced possession limits, in-season possession limit triggers, and other measures to improve management of the skate fisheries. This proposed rule also includes skate fishery specifications for fishing years (FY) 2010 and 2011.

Birds of Golden Pride Project area, Nzega District, central Tanzania ...

African Journals Online (AJOL)

ols 2003; Nichols & Grant 2007; Gould 2011). In some instances ... C. Werema, K.M. Howell, C.A. Msuya, J. Sinclair, A. Macha. 27 .... We thank David Moyer and two anonymous reviewers for constructive comments that greatly ... StevenSOn, t.

Coast Guard Proceedings. Volume 70, Number 3, Fall 2013

Science.gov (United States)

2013-01-01

for Prevention Policy Member Rear Admiral Stephen Metruck Assistant Commandant for Resources, Chief Financial Officer Member Rear Admiral Steven...R. Grawe (Acting) Director of National Pollution Funds Center Member Mr. Gary C. Rasicot Director of Marine Transportation Systems Management

Atypical Hand, Foot, and Mouth Disease Caused by Coxsackievirus A6 in Denmark:

DEFF Research Database (Denmark)

Horsten, Hans-Henrik; Kemp, Michael; Fischer, Thea K

2018-01-01

, vasculitis, syphilis, dermatophytid, erythema multiforme and Stevens-Johnson syndrome. Three adults and 3 children required hospitalization due to extensive skin involvement and fever. All reported patients had laboratory confirmed enterovirus infection. This study demonstrated an upsurge in atypical HFMD...

75 FR 62686 - Health Information Technology: Revisions to Initial Set of Standards, Implementation...

Science.gov (United States)

2010-10-13

... Health Information Technology: Revisions to Initial Set of Standards, Implementation Specifications, and... Health Information Technology (ONC), Department of Health and Human Services. ACTION: Interim final rule... Coordinator for Health Information Technology, Attention: Steven Posnack, Hubert H. Humphrey Building, Suite...

Advancing Global Cancer Research @ AACR 2015

Science.gov (United States)

Research Priorities for NCI’s Center for Global Health' and included presentations on our mission, objectives, currently funded programs, and future programs given by Dr. Lisa Stevens and Paul Pearlman, as well as three special presentations by NCI grantees.

Ostrich: Journal of African Ornithology - Vol 75, No 3 (2004)

African Journals Online (AJOL)

Craig Symes, Mark Brown, Louise Warburton, Michael Perrin, Colleen Downs, 106-109 ... The Birds of Hispaniola (an annotated checklist) by Allan R Keith, James W Wiley, Steven C Latta and JosE9 A Ottenwalder ... WRJ Dean, 184-185.

78 FR 77782 - Qualification of Drivers; Exemption Applications; Vision

Science.gov (United States)

2013-12-24

... A. Lawson (KY) Everett H. Logan (OH) Joseph L. Mast (OR) Jesse R. McClary, Sr. (MO) Kevin L. Moody.... Huelster (OK) Roger D. Kloss (IL) Mark D. Kraft (IL) Steven R. Lechtenberg (NE) Thomas W. Markham (MN) Paul...

Hollywood kohtu ette / Allan Espenberg

Index Scriptorium Estoniae

Espenberg, Allan

2005-01-01

Uruguay plaanib kohtusse kaevata mängufilmi "Sügavuses" ("Submerged") tegijad, kuna linalugu loob sellest Lõuna-Ameerika riigist väära ning mõnitava pildi. Režissöör Anthony Hickox, peaosas Steven Seagal : USA 2005

NCI intramural research highlighted at 2014 AACR meeting

Science.gov (United States)

This year’s American Association for Cancer Research meeting featured plenary talks by two NCI scientists, Steven Rosenberg, M.D., and Louis Staudt, M.D., Ph.D., that highlighted the challenges in developing varied and potentially synergistic treatments f

Indiana Jones on tagasi ja näitab, kuidas käituda / Kristiina Davidjants

Index Scriptorium Estoniae

Davidjants, Kristiina, 1974-

2008-01-01

22 mail esilinastub Steven Spielbergi järjekordne Indiana Jones'i film, kaasstsenaristiks ja produtsendiks George Lucas ja Harrison Fordiga nimiosas "Indiana Jones ja kristallpealuu kuningriik" ("Indiana Jones and the Kingdom of the Crystal Skull"). Saaga varasemast kolmest filmist

Kolm Armastust ja Anarhiat. Helsingist PÖFFile / Maria Ulfsak-Šeripova

Index Scriptorium Estoniae

Ulfsak-Šeripova, Maria, 1981-

2009-01-01

Helsingi käesoleva aasta filmifestivali "Armastus ja Anarhia" filmidest, mis tänavu ka PÖFFile või kohalikku kinolevisse tulevad : Steven Soderberghi "The Informant!" ja "The Girlfriend Experience", Lynn Sheltoni "Humpday" ning Catherine Breillat' "Sinihabe" ("Barbe Bleue")

75 FR 57440 - Performance Review Board Membership

Science.gov (United States)

2010-09-21

... DEPARTMENT OF COMMERCE Performance Review Board Membership AGENCY: Economics and Statistics... the Performance Review Board in accordance with the Economics and Statistics Administration's Senior... Callahan, Nancy M. Gordon, Howard R. Hogan, Arnold A. Jackson, Theodore A. Johnson, Steven J. Jost, J...

78 FR 66785 - SES Performance Review Board

Science.gov (United States)

2013-11-06

... Safety Board. Steven E. Goldberg, Chief Financial Officer, National Transportation Safety Board. John.... Goldberg's rating review). Anthony P. Scardino, Chief Financial Officer, U.S. Patent and Trademark Office... CONTACT: Emily T. Carroll, Chief, Human Resources Division, Office of Administration, National...

So You Want Your Child To Learn French! Second Revised Edition.

Science.gov (United States)

Fleming, Berkeley, Ed.; Whitla, Margaret, Ed.

This collection of essays on early French second language instruction includes: "Why Bilingualism?" (Steven MacKinnon); "French Second-Language Programs: Alternative Approaches" (Henry P. Edwards); "Core French: A Brighter Future" (Janet Poyen, Judy Gibson); "The Parents' Role" (Deborah Whale); "Franco…

empiric treatment based on helicobacter pylori serology cannot ...

African Journals Online (AJOL)

EMPIRIC TREATMENT BASED ON. HELICOBACTER PYLORI SEROLOGY. CANNOT SUBSTITUTE FOR EARLY. ENDOSCOPY IN THE. MANAGEMENT OF DYSPEPTIC. RURAL BLACK AFRICANS. Stephen JD O'Keefe, B Salvador, J Nainkin, S Majikir H. Stevens, A Atherstone. Background_ Evidence that chronic gastric ...

77 FR 38183 - Approval and Promulgation of Implementation Plans and Designations of Areas for Air Quality...

Science.gov (United States)

2012-06-27

... protection, Air pollution control, Carbon monoxide, Incorporation by reference, Intergovernmental relations... materials are available either electronically in www.regulations.gov or in hard copy at the Atmospheric...., excluding Federal holidays. FOR FURTHER INFORMATION CONTACT: In Region 7, Steven Brown, Atmospheric Programs...

E.T. sündis uuesti

Index Scriptorium Estoniae

2002-01-01

Kogupere ulmefilm "E.T. - sõber kaugelt" ("E.T. The Extra-Terrestrial") : režissöör Steven Spielberg : Ameerika Ühendriigid 1982. Restaureeritud ja paari omal ajal välja jäetud stseeniga täiendatud uusversioon

Saladus on tagasi / Jaak Lõhmus

Index Scriptorium Estoniae

Lõhmus, Jaak

2002-01-01

Kogupere ulmefilm "E.T. - sõber kaugelt" ("E.T. The Extra-Terrestrial") : režissöör Steven Spielberg : Ameerika Ühendriigid 1982. Restaureeritud ja paari omal ajal välja jäetud stseeniga täiendatud uusversioon

Muusikauudiseid maailmast / Nele-Eva Steinfeld

Index Scriptorium Estoniae

Steinfeld, Nele-Eva

2016-01-01

Lühisõnumeid maailmast: Suri Nikolaus Harnoncourt. Grammy selleks aastaks jagatud. Claudio Abbado pärand liigub Berliini. Piotr Anderszewski võtab aja maha. Polar Music Prize Cecilia Bartolile. Lahkus USA helilooja Steven Stucky. Händeli kantaadi seni tundmatu versioon

Turvaline tulevik / Meelis Piller

Index Scriptorium Estoniae

Piller, Meelis

2002-01-01

Arutlus kas turvalise tuleviku eelduseks on privaatsusest loobumine. Ka probleemi "turvalisus versus privaatsus" tõstatanud Robert Ludlumi romaanist "Prometheuse pettus" ja ideede käsitlusest Ray Bradbury ulmeteoses "451° Fahrenheiti". Näitena on toodud ka Steven Spielbergi filmi "Minority report"

77 FR 55692 - Establishment of Class E Airspace; Fort Garland, CO

Science.gov (United States)

2012-09-11

... accommodate aircraft using new Area Navigation (RNAV) Global Positioning System (GPS) standard instrument... Airstrip Airport, to accommodate IFR aircraft executing new RNAV (GPS) standard instrument approach..., 2012. Steven L. Vale, Acting Manager, Operations Support Group, Western Service Center. [FR Doc. 2012...

Antenna Development for Multifunctional Armor Applications Using Embedded Spin-Torque Nano-Oscillator (STNO) as a Microwave Detector

Science.gov (United States)

2011-08-09

Elena Bankowski (Research Engineer) & Mr. Steven Zielinski (Engineer). •Oakland University Research Team: Dr. Andrei Slavin (Chair, Physics...Dr. Grace Bochenek, the Chief Scientist Dr. Dave Gorsich and GVSS Associate Director Mr. Steve Knott for their support of this innovative research

Professors of the New Economy.

Science.gov (United States)

Wilson, Robin

2000-01-01

Profiles four professors who epitomize the increasing influence of academe on new technology-driven Internet business: a start-up maven, Steven Kaplan; a social psychologist, Michael Ray; a cyberlawyer, David Post; and an e-commerce expert, Andrew B. Whinston. (DB)

J-GLOBAL MeSH Dictionary: Stevens‐Johnson症候群 [MeCab user dictionary for science technology term[Archive

Lifescience Database Archive (English)

Full Text Available MeCab user dictionary for science technology term Stevens‐Johnson症候群 名詞 一般 * * * * Stevens‐Johnson...症候群 ... MeSH D013262 200906041743408238 C LS51 UNKNOWN_2 Stevens ‐ Johnson 症候群

Refining Lung Cancer Screening Criteria in the Era of Value-Based Medicine.

Directory of Open Access Journals (Sweden)

Steven D Shapiro

2017-02-01

Full Text Available In a Perspective on the Research Article by ten Haaf and colleagues, Steven Shapiro discusses the challenges of identifying screening strategies that maximize the number of cancers diagnosed, while minimizing the harms of overdiagnosis and maintaining cost-effectiveness.

Uudiseid maailmast / Nele-Eva Steinfeld

Index Scriptorium Estoniae

Steinfeld, Nele-Eva

2013-01-01

Lühisõnumeid muusikamaailmast: Tan Dun nimetati UNESCO hea tahte saadikuks. Risë Stevens (1913-2013). San Francisco sümfooniaorkestri streik. Antonio Pappano pole rahul noorte ooperilauljatega. Läti Suure Muusikaauhinna võitjad. Bachi medal Peter Schreierile. Amsterdami Concertgebouw 125

Not a Pound for Air-To-Ground: A Historiographical Analysis on the Genesis of the Multi-Role Fighter

Science.gov (United States)

2015-04-01

Robert M. Quadrennial Defense Review Report. Washington D.C.: Department of Defense, 2010. http://www.defense.gov/qdr/images...dvs=1417624228343~272 (accessed 2 Dec 2014) Stevens, Donald, Bruce Davis, William Stanley, Daniel Norton, Rae Starr, Dnaiel Raymer , John Gibson

Download this PDF file

African Journals Online (AJOL)

Mariana

2016-09-14

Sep 14, 2016 ... 2015) and some trees (Stevens and Pijut, 2014), kanamycin selection is ineffective because of ..... Early-flowering sweet orange mutant ―x11‖ as a model for functional genomic studies of. Citrus. BMC Res. Notes 7: 511.

Keeping Seniors Safe (A Cup of Health with CDC)

Centers for Disease Control (CDC) Podcasts

Falls are the leading cause of injuries among older adults in the U.S. and can result in reduced mobility and loss of independence. In this podcast, Dr. Judy Stevens discusses ways to prevent fall-related injuries among older adults.

Steven Hawking to visit Texas A&M in spring

CERN Multimedia

Xavier, D

2002-01-01

Stephen Hawking will visit Texas A&M University from Feb. 24 to March 21 2003 to participate in the inaugural meeting of the George P. and Cynthia W. Mitchell Institute for Fundamental Physics. This institute will bring several of the world's top physicists to A&M for a month-long exploration of the latest ideas on topics ranging from superstrings to M-theory and supergravity (1/2 page).

Mazeikiu refinery to stay in Yukos' control / Steven Paulikas

Index Scriptorium Estoniae

Paulikas, Steven

2004-01-01

Vene peaprokuratuur andis välja rahvusvahelise vahistamisorderi Mazheikiu Nafta juhatuse esimehe ja Jukose aktsionäri Mihhail Brudno suhtes. Leedu valitsus kaalub võimalikke samme, sealhulgas Mazheikiu Nafta aktsiate tagasiostmist

Analysts : no need to panic over prices / Steven Paulikas

Index Scriptorium Estoniae

Paulikas, Steven

2004-01-01

Pärast EL-iga liitumist on Balti riikides hinnad tõusnud keskmiselt 5,7%, pankade hinnangul on oodata ka inflatsiooni kiirenemist. Lisa: Thank you, accession: Consumer Price Index, percent increase, year-on-year

Meri, munklus ja tööstusmaastik / Kaire Nurk

Index Scriptorium Estoniae

Nurk, Kaire, 1960-

2003-01-01

Video-tegevuskunsti sündmus "Saar 2003" 5. juulil Viinistus ja Mohnil. Osa võtsid Erik Alalooga, sakslased Uwe Schloen ja Georg Janthur, Jaan Toomik, Jaan Paavle, Silja Saarepuu, Villu Plink, Jüri Ojaver, venelanna Tatjana Goloviznina, lõuna-aafriklane Steven Cohen

75 FR 76951 - Submission for OMB Review; Comment Request

Science.gov (United States)

2010-12-10

...: National Oceanic and Atmospheric Administration (NOAA). Title: Foreign Fishing Reporting Requirements. OMB... information collection. Foreign fishing activities are authorized under the Magnuson- Stevens Fishery... which U.S. demand is low relative to the abundance of the species. Affected Public: Business or other...

75 FR 4569 - Government-Owned Inventions; Availability for Licensing

Science.gov (United States)

2010-01-28

... States this year. Women will be disproportionately affected constituting 76% of these new cases... to develop more accurate diagnostic tests to detect thyroid cancer. Inventors: Steven K. Libutti (NCI... necessarily limited to, cancer, inflammation, and tumor progression or regression. Inventors: Thomas H. Bugge...

76 FR 17789 - Fisheries of the Northeastern United States; Atlantic Bluefish Fishery; 2011 Atlantic Bluefish...

Science.gov (United States)

2011-03-31

...-Stevens Act), the NMFS Assistant Administrator has determined that this final rule is consistent with the...: March 28, 2011. Samuel D. Rauch III, Deputy Assistant Administrator for Regulatory Programs, National...; current estimates of fishing mortality; stock status; recent estimates of recruitment; virtual population...

76 FR 80318 - Fisheries of the Northeastern United States; Northeast Multispecies Fishery Management Plan...

Science.gov (United States)

2011-12-23

.... Classification Pursuant to section 304(c)(1)(A) of the Magnuson-Stevens Act, the NMFS Assistant Administrator has..., Deputy Assistant Administrator for Regulatory Programs, National Marine Fisheries Service. For the...-effort (CPUE); discards; stock status; recent estimates of recruitment; virtual population analysis...

Plaadid / Valner Valme

Index Scriptorium Estoniae

Valme, Valner, 1970-

2004-01-01

Uutest heliplaatidest Talib Kweli "The Beautiful Struggle", Evanescence "Anywhere But Home", Fly Pan Am "N'Ecoutez Pas", Status Quo "XS All Areas - The Greatest Hits", Stevens, Shakin "Collectable", Europe "Rock The Night. Very Best Of", Nas "Video Anthology", Nas "Street Disciple", Miossec "1964"

U.S. Navy Capstone Strategies and Concepts: Introduction, Background and Analyses

Science.gov (United States)

2011-12-01

bureaucratically appealing, politically correct, and relatively useless. Gabriel Marcella & Steven Fought “Teaching Strategy in the 21st Century” JFQ...achieve objectives, within the limits imposed by policy Gabriel Marcella & Stephen Fought “Teaching Strategy in the 21st Century” JFQ (2009) 70

76 FR 68358 - Fisheries of the Exclusive Economic Zone Off Alaska; Bering Sea and Aleutian Islands Crab...

Science.gov (United States)

2011-11-04

... action is necessary to improve the quality and timeliness of market information used to conduct... Fishery Conservation and Management Act, the FMP, and other applicable law. DATES: Effective December 5... Fishery Management Council (Council) under the Magnuson-Stevens Fishery Conservation and Management Act...

Cardiac output and vasodilation in the vasovagal response

DEFF Research Database (Denmark)

Wieling, Wouter; Jardine, David L.; de Lange, Frederik J

2016-01-01

. Plethysmographic measurements were intermittent and not frequent enough to capture rapid changes in blood flow during progressive hypotension. However, later investigations by Weissler, Murray, and Stevens performed between 1950 and 1970 used invasive beat-to-beat BP measurements and more frequent measurements...

75 FR 9248 - Endangered and Threatened Wildlife and Plants; Permit Applications

Science.gov (United States)

2010-03-01

... Applications Permit Application Number: TE006012. Applicant: Steven Taylor, Center for Biodiversity, Illinois... State University, Springfield, Missouri. The applicant requests a permit renewal to take (capture and... Application Number: TE02560A. Applicant: Timothy C. Carter, Ball State University, Muncie, Indiana. The...

76 FR 25763 - Qualification of Drivers; Exemption Applications; Vision

Science.gov (United States)

2011-05-05

... with the vision deficiency: Christopher Kahl, Althea Renita Dowell, Steven DuBois, Steve Campbell... Pulido, Oliver Murphy, Jerome Smalls, Alan Jenkins, Ryan Forsythe, Terry L. Randoll, Edward Joseph... for an exemption. Thomas L. Newingham, Joseph Barlow. The following 2 applicants do not have...

A molecular phylogeny of selected species of genus Prunus L ...

African Journals Online (AJOL)

USER

2010-08-02

Aug 2, 2010 ... 52 - 56°C with the primers ITS-9 and ITS-6 or Trn-L and Trn-F. Polymerase chain .... The sub-genus Prunus has also relatively good support (81%) including .... Stevens, Michael J, Donoghue (1999). Plant Systematics. A.

77 FR 55691 - Establishment of Class E Airspace; Circle Town, MT

Science.gov (United States)

2012-09-11

... (RNAV) Global Positioning System (GPS) standard instrument approach procedures at Circle Town County..., at Circle Town County Airport, to accommodate IFR aircraft executing new RNAV (GPS) standard..., Washington on August 30, 2012. Steven L. Vale, Acting Manager, Operations Support Group, Western Service...

77 FR 75598 - Proposed Establishment of Class E Airspace; White Mountain, AK

Science.gov (United States)

2012-12-21

... accommodate aircraft using new Area Navigation (RNAV) Global Positioning System (GPS) standard instrument... RNAV (GPS) standard instrument approach procedures to/from the en route environment at White Mountain... in Seattle, Washington, on November 13, 2012. Steven L. Vale, Acting Manager, Operations Support...

77 FR 55690 - Amendment of Class E Airspace; Dillon, MT

Science.gov (United States)

2012-09-11

... aircraft using new Area Navigation (RNAV) Global positioning System (GPS) standard instrument approach... Airport, Dillon, MT, to accommodate IFR aircraft executing new RNAV (GPS) standard instrument approach.... Steven L. Vale, Acting Manager, Operations Support Group, Western Service Center. [FR Doc. 2012-22269...

Fulltext PDF

Indian Academy of Sciences (India)

R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

Abbott, Dallas, Lamont-Doherty Earth Observatory of the Columbia University, USA. Ahmad, Talat, Delhi University, Delhi. Anderson, Don L, California Institute of Technology, USA. Anderson, Steven, Black Hills State University,USA. Anil Kumar, G, National Geophysical Research Institute, Hyderabad. Asthana, Deepanker ...

Demonstrative Maneuvers for Aircraft Agility Predictions

Science.gov (United States)

2008-03-01

AIAA Paper 1996-3741. 19. Raymer , Daniel P. Aircraft Design: A Conceptual Approach. American Institute of Aeronautics and Astronautics, Inc., 3rd...Shaw, Robert L. Fighter Combat: Tactics and Maneuvering. Naval Institute Press, Annapolis, MD, 1985. 25. Smith, Steven W. The Scientist and

76 FR 59373 - Fisheries of the Caribbean, Gulf of Mexico, and South Atlantic; Generic Annual Catch Limits...

Science.gov (United States)

2011-09-26

... submitting comments. Mail: Rich Malinowski, Southeast Regional Office, NMFS, 263 13th Avenue South, St... http://sero.nmfs.noaa.gov . FOR FURTHER INFORMATION CONTACT: Rich Malinowski, telephone: 727-824- 5305, or e-mail: rich.malinowski@noaa.gov . SUPPLEMENTARY INFORMATION: The Magnuson-Stevens Fishery...

Valehäbita ilusüstidest / Ülle Hõbemägi

Index Scriptorium Estoniae

Hõbemägi, Ülle

2008-01-01

Küsimustele ilusüstide kohta vastavad dr Signe Päär meditsiinilise iluravi keskusest Medemis, meditsiiniliste iluravimeetodite spetsialist ja Londonis asuva esteetilise nahakliiniku Facial Aesthetic Skin Clinik omanik dr Steven Harris ja Rahvusvahelise Esteetilise Meditsiini ja Fotospetsialistide Liidu liige dr Rita Hage

78 FR 61843 - Notice of Intent To Prepare an Environmental Impact Statement: Department of the Army Permit...

Science.gov (United States)

2013-10-04

... resources; essential fish habitat; water quality; cultural resources; geology and soils including... the effects of this proposed action on Essential Fish Habitat per the Magnuson-Stevens Act. The USACE... endangered species and critical habitat. Socioeconomic issues include navigation; induced flooding; land use...

76 FR 30905 - Submission for OMB Review; Comment Request

Science.gov (United States)

2011-05-27

... DEPARTMENT OF COMMERCE Submission for OMB Review; Comment Request The Department of Commerce will... exempted educational activities with respect to Atlantic HMS. Since the Magnuson-Stevens Act does not... commercial or recreational fishing platforms. To regulate these fishing activities, NMFS needs information to...

76 FR 1602 - Proposed Information Collection; Comment Request; Scientific Research, Exempted Fishing, and...

Science.gov (United States)

2011-01-11

... educational activities with respect to Atlantic HMS. Since the Magnuson-Stevens Act does not consider... recreational fishing platforms. To regulate these fishing activities, NMFS needs information to determine the... Review: Regular submission (extension of a currently approved collection). Affected Public: Non-profit...

Ver o que aconteceu: Cinema e Histria em Griffith e Spielberg Regarding what happened: Cinema and History in Griffith and Spielberg

Directory of Open Access Journals (Sweden)

Eduardo Victorio Morettin

2012-01-01

Full Text Available O objetivo deste texto discutir as conexes entre o discurso histrico e cinematogrfico, a partir das estratgias de autenticao em O Nascimento de uma Nao (The Birth of Nation, 1915, de David Griffith, e Amistad (1997, de Steven Spielberg. Sero examinadas as leituras que os filmes fazem da representao do tema da escravido e os vnculos com o contexto em que foram produzidos, analisando tambm as questes de estilo presentes nas duas obras.This text aims at discussing the connections between the historical and cinematographic discourse, starting from the authentication strategies employed by two films: The Birth of Nation (1915, from David Griffith, and Amistad (1997, from Steven Spielberg. This article will examine the different interpretations of the slavery theme and the link to the context in which they were produced, including the analysis of the style used on these two films.

A reanalysis of Lord's statistical treatment of football numbers

NARCIS (Netherlands)

Zand Scholten, A.; Borsboom, D.

2009-01-01

Stevens’ theory of admissible statistics [Stevens, S. S. (1946). On the theory of scales of measurement. Science, 103, 677680] states that measurement levels should guide the choice of statistical test, such that the truth value of statements based on a statistical analysis remains invariant under

Google de pest

NARCIS (Netherlands)

Voorde, M. ter; Jong, S.M. de

2010-01-01

Het klinkt als een bizarre onderneming: wie gaat er nou bacteriën, organismen van pakweg een duizendste millimeter, opsporen met satellietbeelden? Toch gebeurt het sinds kort. Met behulp van satellietbeelden van Google Earth proberen Elisabeth Addink en Steven de long, fysisch-geografen van de

36 CFR 213.1 - Designation, administration, and development of National Grasslands.

Science.gov (United States)

2010-07-01

..., Power. Kansas Cimarron Morton, Stevens. Nebraska Oglala Dawes, Sioux. New Mexico Kiowa Colfax, Harding... TENANT ACT BY THE FOREST SERVICE § 213.1 Designation, administration, and development of National... Tenant Act. (c) The National Grasslands shall be administered under sound and progressive principles of...

Running across Europe: The rise and size of one of the largest sport markets

NARCIS (Netherlands)

Scheerder, J.; Breedveld, K.

2015-01-01

Who is doing a run with the running boom? The growth and governance of one of Europe's most popular sport activities / Jeroen Scheerder, Koen Breedveld and Julie Borgers -- Belgium (Flanders): trends and governance in running / Julie Borgers, Steven Vos and Jeroen Scheerder -- Denmark: running for

Sõjas nagu sõjas ikka / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2006-01-01

10-osaline sõjaseriaal "Relvavennad" ("Band of Brothers") ajalooprofessor Stephen Ambrose'i raamatu järgi : produtsendid Tom Hanks, Steven Spielberg : režissöörid Tom Hanks, David Frenkel jt. : Ameerika Ühendriigid - Suurbritannia 2001. Lühidalt ka teistest ilmasõda kajastavatest seriaalidest

An Integrated Modeling and Observational Study of Three-Dimensional Upper Ocean Boundary Layer Dynamics and Parameterizations

Science.gov (United States)

2012-04-26

for public release ; distribution is unlimited. 4 Figure 3. First Kuroshio survey. Colors show MODIS SST image. Inset shows the survey...Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD 20892, USA. *To whom correspondence should be addressed. E-mail: stevens@scripps.edu 15

Steve Jobs, Ameerika Hans H. Luik / Kertu Ruus

Index Scriptorium Estoniae

Ruus, Kertu, 1977-

2007-01-01

Autor võrdleb Apple'i asutajat ja juhti Steve Jobsi Eesti meediaärimehe Hans H. Luigega. Vt. samas: Jobs: ärge raisake aega teiste elu elamisele; Forbes: iPhone'ist saab Apple'i suur hitt; CV: Steven Paul Jobs. Diagramm: Apple'i aktsia

76 FR 20551 - Changes in Flood Elevation Determinations

Science.gov (United States)

2011-04-13

... Daily Schillerstrom, Chairman, 05-1256P). Herald. DuPage County Board, Jack T. Knuepfer Administration... Chairman, Board of Spectator. Selectmen, Swansea Town Hall Annex, 68 Stevens Road, Swansea, MA 02777...). 8, 2010, The Easton Administrator, Enterprise News. 136 Elm Street, Easton, MA 02356. Bristol Town...

Constructivism as the Framework for International Orders

Science.gov (United States)

2016-09-01

idea that each kingdom had a right to sovereign control of its territory, laying the groundwork for our modern concept of the state.5 These shared...Washington, DC: NDU Press, 2013), Chapter 1 “Deviant Globalization” by Nils Gilman, Jesse Goldhammer, and Steven Weber , 3.

76 FR 30265 - Fisheries of the Northeastern United States; Monkfish; Amendment 5

Science.gov (United States)

2011-05-25

.... Response: This comment seems to be based on a misunderstanding of the management measures in Amendment 5... Monkfish Fishery Management Plan (FMP). The New England and Mid-Atlantic Fishery Management Councils... accountability measure (AM) requirements of the Magnuson-Stevens Fishery Conservation and Management Act...

Military Airpower: A Revised Digest of Airpower Opinions and Thoughts

Science.gov (United States)

2007-03-01

Opinions and Thoughts Air University Press Team Chief Editor Jeanne Shamburger Copy Editor Sherry Terrell Cover Art and Book...Design Steven C. Garst Illustrations Daniel Armstrong Composition and Prepress Production Ann Bailey Quality Review Mary J. Moore Print Preparation Joan Hickey Distribution Diane Clark

Speeding up detection of SHA-1 collision attacks using unavoidable attack conditions

NARCIS (Netherlands)

M.M.J. Stevens (Marc); D. Shumow

2017-01-01

textabstractCounter-cryptanalysis, the concept of using cryptanalytic techniques to detect cryptanalytic attacks, was introduced by Stevens at CRYPTO 2013 [22] with a hash collision detection algorithm. That is, an algorithm that detects whether a given single message is part of a colliding message

117 - 122 Omoniyi et al

African Journals Online (AJOL)

User

The level of total-Cr ions was determined in the serum, red blood cell, plasma and fur of ... mammals by maintaining efficient glucose, lipid, and protein metabolism ..... Steven, J.D., Davies, L.J, Stanley, E.K, Abbott, R.A.,. Ihnat, M., Bidstrup, L., ...

to view fulltext PDF

Indian Academy of Sciences (India)

Madhu

ROS network is essential to induce disease resistance and even to mediate resistance to multiple stresses in ...... campestris and French bean mesophyll cells; Plant J. 15 .... He Y, Tang R H, Hao Y, Stevens R D, Cook C W, Ahn S M, Jing L,.

77 FR 21977 - Whitestone Power and Communications; Notice Concluding Pre-Filing Process and Approving Process...

Science.gov (United States)

2012-04-12

... Communications (Whitestone). e. Name of Project: Microturbine Hydrokinetic River-In-Stream Energy Conversion.... Applicant Contact: Steven M. Selvaggio, Whitestone Power and Communications, P.O. Box 1630, Delta Junction... Microturbine Hydrokinetic River-In-Stream Energy Conversion Power Project would consist of: (1) A 12-foot-wide...

Armastusest nii ja teisiti / Laurence Lumiere

Index Scriptorium Estoniae

Lumiere, Laurence

2007-01-01

Romantiline komöödiafilm "Viimane suudlus" ("The Last Kiss") : režissöör Tony Goldwyn : Ameerika Ühendriigid, 2006 ja põnevusfilm "Ghost Rider - põrguline" : režissöör Mark Steven : peaosas Nicolas Cage : Ameerika Ühendriigid, 2007

78 FR 70057 - Agency Information Collection Activities: Submission for OMB Review; Comment Request

Science.gov (United States)

2013-11-22

... U.S.C. 3501-3520), federal agencies must obtain approval from the Office of Management and Budget... collection contact Steven Johnson at 410-786-3332.) 4. Type of Information Collection Request: Reinstatement...: November 19, 2013. Martique Jones, Deputy Director, Regulations Development Group, Office of Strategic...

Interview til debat

DEFF Research Database (Denmark)

Larsen, Tobias Boelt

2016-01-01

Artiklen beskæftiger sig med, hvordan journalist Martin Krasnik med sine interviewteknikker bryder med interviewformatet, som vi kender det, samt hvilke konsekvenser disse brud kan have. På baggrund af blandt andre John Heritage og Steven Clayman samt Emanuel Schegloffs undersøgelser af, hvordan ...

Una guía sobre las aves de Colombia

Directory of Open Access Journals (Sweden)

Jorge E. Orejuela G.

1988-10-01

Full Text Available A guide to the birds of Colombia. Steven L. Hilty y William L. Browm. Ilustrador principal: Guy Tudor, con planchas de H. W. Trimm. J. Gwynne, J. Yrizarry y P. Prall. Dibujos de M. Kleinbaunm. Princenton University Press, Princenton (Nueva Jersey, 1986.

Modifying the properties of 4f single-ion magnets by peripheral ligand functionalisation

DEFF Research Database (Denmark)

Pedersen, Kasper Steen; Ungur, Liviu; Sigrist, Marc

2014-01-01

allows for the extraction of the sign and magnitude of all symmetry-allowed Stevens parameters. The parameter values and the energy spectrum derived from INS are compared to the results of state-of-the-art ab initio CASSCF calculations. Temperature-dependent alternating current (ac) susceptibility...

50 CFR 600.1104 - Bering Sea and Aleutian Islands (BSAI) crab species fee payment and collection system.

Science.gov (United States)

2010-10-01

... endorsement for Norton Sound red king. More specifically, the reduction endorsement fisheries, and the crab... COMMERCE MAGNUSON-STEVENS ACT PROVISIONS Specific Fishery or Program Fishing Capacity Reduction Regulations....1012 of subpart L, establish: (i) The borrower's obligation to repay a reduction loan, and (ii) The...

Pernilla Craig Flight Around Lac Leman

CERN Multimedia

Goldfarb, Steven

2013-01-01

Aviator and future physicist Pernilla Craig visits CERN and is hosted by the Geneva Flight Club. Web pioneer Robert Cailliau helps in the preparations, flight instructor Aline Cosmetatos takes the co-pilot seat, and ATLAS outreach coordinator Steven Goldfarb serves cocktails from the back seat.

Sõjafilmide ideoloogia muutumisest (seoses sisulise väljenduse ja vormiliste vahendite muutumisega) / Martin Oja

Index Scriptorium Estoniae

Oja, Martin, 1978-

2007-01-01

Sõjafilmide ideoloogilisest tasandist. Tähelepanekuid ja märkusi nelja filmi põhjal: "Casablanca" (rezh. Michael Curtiz, 1942), "Iwo Jima liivad" (rezh. Allan Dwan, 1949), "Reamees Ryani päästmine" (rezh. Steven Spielberg, 1998), "Vaenlane väravas" (rezh. Jean-Jacques Annaud, 2001)

Theatre Review | Various Authors | Shakespeare in Southern Africa

African Journals Online (AJOL)

Twelfth Night: The Port Elizabeth Shakespearean Festival, February 2004; Macbeth: Directed by Geoffrey Hyland, Maynardville Open Air Theatre, January to. February 2004; The Marowitz Hamlet: Directed by Floyed de Vaal for the University of. Stellenbosch Drama Department, July 2004; Bollywood Twelfth Night: Steven ...

Science.gov (United States)

1994-07-27

On target: Anthony Stevens and his sister Joanna, raised £500 during last week's 1994 Cadbury Strollerthon. Proceeds from the walk will be divided between a project to help improve the mobility of children with disabilities in the UK and Save the Children overseas schemes.

77 FR 19282 - Draft NPDES General Permit for Discharges From the Oil and Gas Extraction Point Source Category...

Science.gov (United States)

2012-03-30

... adversely affect an Essential Fish Habitat is subject to the consultation provisions of the Manguson-Stevens Act. The Texas Coastal Subcategory areas covered by this general permit include Essential Fish Habitat... would be unlikely to adversely affect Essential Fish Habitat. EPA received written [[Page 19284...

77 FR 65547 - Reissuance of the NPDES General Permits for Oil and Gas Exploration Facilities on the Outer...

Science.gov (United States)

2012-10-29

... designated critical habitat areas. Essential Fish Habitat. The Magnuson-Stevens Fishery Conservation and... affect an Essential Fish Habitat (EFH). EPA's EFH assessments conclude that the discharges authorized by... consult with the National Marine Fisheries Service (NMFS) and the U.S. Fish and Wildlife Service (USFWS...

Euwin the second year

NARCIS (Netherlands)

Dhondt, S.; Totterdill, P.

2014-01-01

In dit rapport aan de Europese Commissie beschrijven Steven Dhondt en Peter Totterdill de activiteiten, de resultaten en de impact van het EUropean Workplace INnovation (EUWIN) netwerk in haar tweede jaar. EUWIN dat werd opgericht in 2013, helpt de EU en zijn bedrijfsleven arbeidsorganisaties te

Efficient Computations and Representations of Visible Surfaces.

Science.gov (United States)

1979-12-01

position as stated. The smooth contour generator may lie along a sharp ridge, for instance. Richards & Stevens -28- 6m lace contout s ?S ,.......... ceoonec...From understanding computation to understanding neural circuitry. Neurosci. Res. Prog. Bull. 13. 470-488. Metelli, F. 1970 An algebraic development of

76 FR 25295 - Fisheries of the Exclusive Economic Zone Off Alaska; Bering Sea and Aleutian Islands King and...

Science.gov (United States)

2011-05-04

... following methods: Electronic Submissions: Submit all electronic public comments via the Federal eRulemaking... of the Magnuson-Stevens Act, as amended in 2007, establish, either expressly or by logical extension... sustainable yield. Tier 4 stocks have a stock assessment model that estimates biomass using the historical...

MicroRNA and gene signature of severe cutaneous drug ...

African Journals Online (AJOL)

Purpose: To build a microRNA and gene signature of severe cutaneous adverse drug reactions (SCAR), including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Methods: MicroRNA expression profiles were downloaded from miRNA expression profile of patients' skin suffering from TEN using an ...

ACUTE AND CHRONIC TOXICITY OF BREVETOXIN TO OYSTERS AND GRASS SHRIMP

Science.gov (United States)

Walker, Calvin C., James T. Winstead, Steven S. Foss, Janis C. Kurtz, James Watts, Jeanne E. Scott and William S. Fisher. In press. Acute and Chronic Toxicity of Brevetoxin to Oysters and Grass Shrimp (Abstract). To be presented at the SETAC Fourth World Congress, 14-18 November ...

The Casualty Network System Capstone Project

Science.gov (United States)

2012-12-01

described by the Watts and Strogatz model (Watts & Strogatz , 1998). Based on the Watts and Strogatz model, the AF can be viewed as a small world...chemical casualties handbook (Vol. 7). Fort Detrick, MD: U.S. Government Printing Office. Watts, Duncan, & Strogatz , Steven (1998). Collective dynamics of

76 FR 40674 - Fisheries of the Exclusive Economic Zone Off Alaska; Scallops

Science.gov (United States)

2011-07-11

... accountability measures (AMs) to prevent overfishing in the target fishery for weathervane scallops. Implementing... statewide estimate of spawning biomass for weathervane scallops, the overfishing level (OFL) is specified as...-Stevens Act relative to preventing overfishing and establishing an ABC and ACL. The following is a summary...

75 FR 57734 - Fisheries of the Caribbean, Gulf of Mexico, and South Atlantic; Snapper-Grouper Fishery off the...

Science.gov (United States)

2010-09-22

... measures (AMs) for nine snapper-grouper species, eight of which are undergoing overfishing; specify... address overfishing of eight snapper-grouper species while maintaining catch levels consistent with...-Stevens Act in 2006 require that if a stock or stock complex in an FMP is undergoing overfishing, the FMP...

75 FR 57974 - Senior Executive Service Performance Review Board

Science.gov (United States)

2010-09-23

.... Crocetti Jr., Louis D. Cullen, Susan M. Cummiskey, Chris Daitch, William Davis, Delia P. Dayton, Mark de.... Armstrong, Charles R. Ayala, Janice Aytes, Michael L. Bacon, Roxana Baldwin, William D. Baroukh, Nader Barr... Brundage, William Bucella, Donna A. Bucher, Steven P. Buckingham, Patricia A. Burke, Richard Butcher...

Representing chemicals using OWL, description graphs and rules

CSIR Research Space (South Africa)

Hastings, J

2010-06-01

Full Text Available OWL, Description Graphs and Rules Janna Hastings1;2;3?, Michel Dumontier4, Duncan Hull1, Matthew Horridge5, Christoph Steinbeck1, Ulrike Sattler5, Robert Stevens5, Tertia H orne2, and Katarina Britz2;3 1 European Bioinformatics Institute, UK 2...

Representing chemicals using OWL, description graphs and rules

CSIR Research Space (South Africa)

Hastings, J

2010-06-01

Full Text Available , Description Graphs and Rules Janna Hastings1;2;3?, Michel Dumontier4, Duncan Hull1, Matthew Horridge5, Christoph Steinbeck1, Ulrike Sattler5, Robert Stevens5, Tertia H orne2, and Katarina Britz2;3 1 European Bioinformatics Institute, UK 2 University...

76 FR 49423 - Fisheries of the Exclusive Economic Zone Off Alaska; Bering Sea and Aleutian Islands Crab...

Science.gov (United States)

2011-08-10

... market information used to conduct arbitration proceedings. This action is intended to promote the goals and objectives of the Magnuson-Stevens Fishery Conservation and Management Act, the FMP, and other... Conservation and Management Act. Amendments 18 and 19 to the FMP implemented the CR Program. Regulations...

77 FR 74186 - Ocean Transportation Intermediary License Applicants

Science.gov (United States)

2012-12-13

... Logistics, Inc. (NVO & OFF), 7685 NW. 80th Terrace, Medley, FL 33166, Officers: Hugo E. Martinez, Secretary... & OFF), 1834 Harden Blvd., Lakeland, FL 33803, Officers: Steven C. Pniewski, Manager (QI), Manuel R. Echevarria, President, Application Type: New NVO & OFF License, Global Wide Logistics, Inc. (NVO), 1937 Davis...

78 FR 43202 - Ocean Transportation Intermediary License Applicants

Science.gov (United States)

2013-07-19

.... Alsea Global Logistics, LLC dba Alsea Global Logistics (NVO & OFF), 4836 SE Powell Blvd., Portland, OR... NVO & OFF License. Atlant Consulting Inc. dba Avro Logistics (NVO & OFF), 3626 Geary Blvd., Suite 206..., Officers: Paul Selvage, Member (QI), Steven Periman, Member/Manager, Application Type: Add Trade Name Blu...

76 FR 82264 - Fisheries of the Caribbean, Gulf of Mexico, and South Atlantic; Comprehensive Annual Catch Limit...

Science.gov (United States)

2011-12-30

..., to the extent practicable, adverse social and economic effects. The Magnuson-Stevens Act provides the...-hire harvest. Producer surplus represents profit in the for- hire sector. Producer surplus estimates... legally retain wreckfish, by definition, producer surplus due to the harvest of wreckfish is zero. A study...

Reducing Power Differentials in the Classroom Using Student-Based Quantitative Research Scenarios: Applications in Undergraduate and Graduate Research Methods Classrooms

Science.gov (United States)

Morrow, Jennifer Ann; Kelly, Stephanie; Skolits, Gary

2013-01-01

Understanding and conducting research is a complex, integral skill that needs to be mastered by both undergraduate and graduate students. Yet many students are reluctant and often somewhat apprehensive about undertaking research and understanding the underlying statistical methods used to evaluate research (Dauphinee, Schau, & Stevens, 1997).…

78 FR 59635 - Fisheries of the Caribbean, Gulf of Mexico, and South Atlantic; Snapper-Grouper Fishery Off the...

Science.gov (United States)

2013-09-27

... Magnuson-Stevens Act requires fishery managers to end overfishing of stocks and to minimize bycatch and..., which would lower overall cost, or as a marketing tool to attract additional angler trips, which could... illegal, this practice could pose problems in tracking recreational versus commercial landings of snapper...

76 FR 54217 - Pacific Fishery Management Council; Public Meeting

Science.gov (United States)

2011-08-31

... Pacific Fishery Management Council (Pacific Council) will convene a meeting of the Stock Assessment Review... 2011 stock assessment for Pacific sardine, which will be used to develop management measures for the... 305(c) of the Magnuson-Stevens Fishery Conservation and Management Act, provided the public has been...

76 FR 20959 - Pacific Fishery Management Council; Public Meeting

Science.gov (United States)

2011-04-14

... Pacific Fishery Management Council (Pacific Council) will convene a Pacific mackerel Stock Assessment... of the meeting is to review the Pacific mackerel stock assessment for 2011, in order to inform... action under Section 305(c) of the Magnuson-Stevens Fishery Conservation and Management Act, provided the...

76 FR 17411 - Notice of Intent To File License Application, Filing of Pre-Application Document, and Approving...

Science.gov (United States)

2011-03-29

... No. Rock Island, IL.... Drury, IL. 16. Muscatine, IA...... Sweetland, IA. P-13456 Mississippi Lock... section 305(b) of the Magnuson-Stevens Fishery Conservation and Management Act and implementing... Conservation and Management Act, and section 106 of the National Historic Preservation Act. m. Free Flow Power...

Attempted - to -Phase Conversion of Croconic Acid via Ball Milling

Science.gov (United States)

2017-05-18

ARL-TN-0824 MAY 2017 US Army Research Laboratory Attempted α- to β-Phase Conversion of Croconic Acid via Ball Milling by...Laboratory Attempted α- to β-Phase Conversion of Croconic Acid via Ball Milling by Steven W Dean, Rose A Pesce-Rodriguez, and Jennifer A Ciezak...

76 FR 54753 - Whitestone Power and Communications; Notice of Intent To File License Application, Filing of...

Science.gov (United States)

2011-09-02

... of Project: Microturbine Hydrokinetic River-In-Stream Energy Conversion Power Project (also known as... Contact: Steven M. Selvaggio, Whitestone Power and Communications, P.O. Box 1630, Delta Junction, Alaska... Hydrokinetic River-In-Stream Energy Conversion Power Project) and number (P-13305-002), and bear the heading...

Static Scene Statistical Non-Uniformity Correction

Science.gov (United States)

2015-03-01

Covari- ances and Arbitrary-Order Statistical Moments. Technical Report SAND2008-6212, Sandia National Labs, 2008. [21] Perry, David L. and Eustace L...Oxford University Press, Inc., New York, 5th edition, 2004. [30] Stettner, Roger, Howard Bailey, and Steven Silverman . Three dimensional Flash LADAR focal

Milk production and distribution in low-dose counties for the Hanford Thyroid Disease Study

International Nuclear Information System (INIS)

Schimmel, J.G.

1992-06-01

This report identifies sources of milk consumed by residents of Ferry, Okanogan, and Stevens Counties. This information will be used by the Hanford thyroid Disease Study to determine whether thyroid disease has been increased among people exposed to past iodine--131 emissions from Hanford Site Facilities

Vancomycin-resistant enterococci colonization in patients with ...

African Journals Online (AJOL)

Routine surveillance culture for VRE should be considered with respect to the conditions of ... chemotherapy and undergo allogeneic hematopoietic stem cell transplantation with prior conditioning chem- .... Mantle-cell lymphoma ..... cancer. Clin Infect Dis 2002;34:730-51. 13. De Pauw B, Walsh TJ, Donnelly JP, Stevens DA,.

When the War Doesn’t End: Detainees in Legal Limbo

Science.gov (United States)

2014-05-01

it most. While the images of Abu Ghraib may have been forgotten by many, the limitless detention laws provide a legal basis that allows many to...11 Detainee Policy: Popular President Meets Unified Government. Universitat der Bundeswehr 2013, 92. 35 Strasser, Steven 2004. The Abu Ghraib

Generalized coupled wake boundary layer model: applications and comparisons with field and LES data for two wind farms

NARCIS (Netherlands)

Stevens, Richard Johannes Antonius Maria; Gayme, Dennice F.; Meneveau, Charles

2016-01-01

We describe a generalization of the coupled wake boundary layer (CWBL) model for wind farms that can be used to evaluate the performance of wind farms under arbitrary wind inflow directions, whereas the original CWBL model (Stevens et al., J. Renewable and Sustainable Energy 7, 023115 (2015))

Rünnak vaatemängu ajastule / Katrin Kivimaa

Index Scriptorium Estoniae

Kivimaa, Katrin, 1969-

2000-01-01

Rahvusvaheline videokunsti ja uue meedia festival "Video Positive 2000" Liverpoolis üldteemal "The Other Side of Zero". Kontseptsiooni autor Steven Bode. Pikemalt sotsiaalsetest projektidest Internetis ja Iliyana Nedkova kureeritud näitusest "Spacecraft", kus oli väljas ka Mare Tralla töö "silm-vaatlusõhupall"

50 CFR 600.760 - Fishery Negotiation Panel lifetime.

Science.gov (United States)

2010-10-01

... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Fishery Negotiation Panel lifetime. 600... ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MAGNUSON-STEVENS ACT PROVISIONS Fishery Negotiation Panels § 600.760 Fishery Negotiation Panel lifetime. (a) An FNP shall terminate upon either: (1) Submission of...

Spacepower for Australias Security - Grand Strategy or Strategy of Grandeur

Science.gov (United States)

2012-06-01

2000), 34–35; Also see Peter H Diamandis and Steven Kotler , Abundance: The Future Is Better Than You Think (New York: Free Press, 2012... Kotler . Abundance: The Future Is Better Than You Think. New York: Free Press, 2012. DOD. “National Security Space Strategy -Unclassified Summary

Kuifjes katholieke jeugd. De katholieke achtergrond van Hergé. Deel 1 van 2

NARCIS (Netherlands)

de Groot, C.N.

2013-01-01

Following the launch of Steven Spielberg’s ‘Tintin and the Secret of the Unicorn’, l’Osservore Romano hailed Tintin as a ‘catholic hero’. This article demonstrates that the comic originates, more specifically, in conservative and reactionary milieus in Belgian Catholicism. Hergé (ps. for Georges

77 FR 29981 - Fisheries of the Gulf of Mexico; Southeast Data, Assessment, and Review (SEDAR); Public Meetings

Science.gov (United States)

2012-05-21

... describes the fisheries, evaluates the status of the stock, estimates biological benchmarks, projects future... population models to evaluate stock status, estimate population benchmarks and Magnuson-Stevens... assessment of the Gulf of Mexico stock of red snapper will consist of a series of three workshops: a Data...

77 FR 7000 - Fisheries of the Northeastern United States; Northeast Multispecies Fishery; Gulf of Maine Winter...

Science.gov (United States)

2012-02-10

... 2010, 2011, and 2012. A new peer reviewed benchmark stock assessment review (SARC 52) was completed for... opportunity that otherwise might be foregone. The new information from the GOM winter flounder benchmark stock... Conservation and Management Act (Magnuson-Stevens Act). This action implements new stock status determination...

Reverse-Engineering of the Cryptanalytic Attack Used in the Flame Super-Malware

NARCIS (Netherlands)

M.J. Fillinger (Max); M.M.J. Stevens (Marc)

2016-01-01

textabstractIn May 2012, a highly advanced malware for espionage dubbed Flame was found targeting the Middle-East. As it turned out, it used a forged signature to infect Windows machines by MITM-ing Windows Update. Using counter-cryptanalysis, Stevens found that the forged signature was made

Reverse-Engineering of the Cryptanalytic Attack Used in the Flame Super-Malware

NARCIS (Netherlands)

M.J. Fillinger (Max); M.M.J. Stevens (Marc); T. Iwata; J.H. Cheon

2015-01-01

textabstractIn May 2012, a highly advanced malware for espionage dubbed Flame was found targeting the Middle-East. As it turned out, it used a forged signature to infect Windows machines by MITM-ing Windows Update. Using counter-cryptanalysis, Stevens found that the forged signature was made

Keeping Track of Your Blood Sugar (For Kids)

Science.gov (United States)

... diabetes care plan. The more information you, your parents, and your diabetes health care team have, the easier it is to keep your blood sugar levels under control. And when they're under control, diabetes isn't controlling you — you're controlling it! Reviewed by: Steven ...

Electrochemical Impedance Spectrometer with an Environmental Chamber for Rapid Screening of New Precise Copolymers

Science.gov (United States)

2017-10-07

12-Oct-2017 Publication Identifier: First Page #: Volume: Date Submitted: 10/7/17 12:00AM Authors: Eric J. Bailey, Philip J. Griffin, Vera ...Stevens, Manuel Marechal, Demi E . Moed, Hakima Mendil-Jakani, Patrice Rannou, Kenneth B. Wagener, and Karen I. Winey Distribution Statement: 1-Approved

Spielberg's "Lincoln" Fulfills the President's Emancipation Legacy

Science.gov (United States)

Wolfford, David

2013-01-01

Steven Spielberg's latest movie "Lincoln" updates Americans' national understanding of their sixteenth president and provides a partial, artful lesson on the passage of the Thirteenth Amendment that abolished slavery. Starring Daniel Day-Lewis, this movie will become a defining work on President Abraham Lincoln's character and leadership…

77 FR 20337 - Fisheries Off West Coast States; Pacific Coast Groundfish Fishery; Advance Notice of Proposed...

Science.gov (United States)

2012-04-04

... 2012. The rulemaking for RAW 2 would take in to account the Council's September 2012 recommendation and... with the court's December 22, 2011, summary judgment ruling, the Magnuson-Stevens Fishery Conservation... found at http://www.pcouncil.org/council-operations/council-meetings/ . NMFS plans to publish at least...

reasons for change of anti-retroviral therapy (art) drugs

African Journals Online (AJOL)

2013-12-01

Dec 1, 2013 ... these factors that have a bearing on compliance and success of treatment. Objective: To determine ... Steven Johnson Syndrome, pancreatitis) and probable failure of to HAART. CD4+ cell ... Indeed,. HAART has transformed HIV disease into a chronic .... Factors independently associated with a greater risk.

Lean IT partnering : How partners create value by developing a lean culture for IT supply and management

NARCIS (Netherlands)

Zee, van der J.T.M.; Blijleven, V.B; Gong, Y.

2015-01-01

Lean, as a philosophy, has been around for quite some time, predominantly in the manufacturing domain. Since the 1990s Lean management provides organizations with a way to achieve superior performance by focusing on customer value, innovation and productivity. In 2011 Steven Bell and Michael Orzen

75 FR 7443 - Western Pacific Fishery Management Council; Public Meeting

Science.gov (United States)

2010-02-19

... definition of shortline fishing gear 5. Non-commercial fishing for Pelagic Management Unit Species in Rose.... The PPT will meet as late as necessary to complete scheduled business. Although non-emergency issues... emergency action under section 305(c) of the Magnuson-Stevens Fishery Conservation and Management Act...

75 FR 21600 - Groundfish Fisheries of the Bering Sea and Aleutian Islands Area and the Gulf of Alaska; King and...

Science.gov (United States)

2010-04-26

... Essential Fish Habitat (EFH) pursuant to the Magnuson-Stevens Fishery Conservation and Management Act.... ACTION: Notification of a call for proposals for Habitat Areas of Particular Concern (HAPCs) and... specific types or areas of habitat within EFH as HAPCs based on the following considerations: (1) the...

30 CFR 285.803 - How must I conduct my approved activities to protect essential fish habitats identified and...

Science.gov (United States)

2010-07-01

... protect essential fish habitats identified and described under the Magnuson-Stevens Fishery Conservation... Act? (a) If, during the conduct of your approved activities, MMS finds that essential fish habitat or... adverse affects on Essential Fish Habitat will be incorporated as terms and conditions in the lease and...

Can Education Reform in Iraq Build a Better Peace?

Science.gov (United States)

2009-05-01

necessarily as closely related to the facts as a westerner may assume. The use of Arabic language, a product of Bedouin poetry and storytelling , is...1996. Johnson, Steven. Emergence: The Connected Lives of Ants, Brains , Cities, and Software. New York: Scribner, 2004. Kaye, Dalia Dassa. More

CWI cryptanalyst discovers new cryptographic attack variant in Flame spy malware

NARCIS (Netherlands)

M.M.J. Stevens (Marc); R.J.F. Cramer (Ronald)

2012-01-01

htmlabstractCryptanalyst Marc Stevens from the Centrum Wiskunde & Informatica (CWI) in Amsterdam, known for breaking the https security in 2008 using a cryptanalytic attack on MD5, analyzed the recent Flame virus this week. He discovered that for this spy malware an as yet unknown cryptographic

78 FR 69823 - Atlantic Highly Migratory Species; Exempted Fishing, Scientific Research, Display, and Chartering...

Science.gov (United States)

2013-11-21

... display and educational activities with respect to Atlantic HMS. Since the Magnuson-Stevens Act does not... during that research, NMFS may consider those vessels as bona fide research platforms while conducting..., NMFS review of public comments received on this notice, an applicant's reporting history on past...

To explain the world the discovery of modern science

CERN Document Server

Weinberg, Steven

2015-01-01

A masterful commentary on the history of science from the Greeks to modern times, by Nobel Prize-winning physicist Steven Weinberg—a thought-provoking and important book by one of the most distinguished scientists and intellectuals of our time. In this rich, irreverent, and compelling history, Nobel Prize-winning physicist Steven Weinberg takes us across centuries from ancient Miletus to medieval Baghdad and Oxford, from Plato’s Academy and the Museum of Alexandria to the cathedral school of Chartres and the Royal Society of London. He shows that the scientists of ancient and medieval times not only did not understand what we understand about the world—they did not understand what there is to understand, or how to understand it. Yet over the centuries, through the struggle to solve such mysteries as the curious backward movement of the planets and the rise and fall of the tides, the modern discipline of science eventually emerged. Along the way, Weinberg examines historic clashes and collaborations betw...

Theory of Magnetic Properties of Heavy Rare Earth Metals:

DEFF Research Database (Denmark)

Lindgård, Per-Anker; Danielsen, O.

1975-01-01

results are given for the magnetization agreeing with experiment for Gd, Tb, and Dy. For Tb and Dy the zero-point deviations were found to be 0.05μB and 0.08μB, respectively, and the ratio [b(T)-b(0)]/[ΔM(T)-ΔM(0)] is approximately 1/3 for all temperatures below 100 K. This gives rise to large corrections......The contributions to the macroscopic-anisotropy constants and resonance energy from crystal-field anisotropy, magnetoelastic effects in the frozen and flexible lattice model, and two-ion interactions have been found for all terms allowed in a crystal of hexagonal symmetry. The temperature...... dependence is expressed as expansions of thermal averages of the Stevens operators 〈Olm〉. A systematic spin-wave theory, renormalized in the Hartree-Fock approximation, is developed and used to find the temperature dependence of the Stevens operators and the resonance energy in terms of the magnetization...

Energy trapping of thickness-extensional modes in thin film bulk acoustic wave filters

Directory of Open Access Journals (Sweden)

Zinan Zhao

2016-01-01

Full Text Available This paper presents the thickness-extensional vibration of a rectangular piezoelectric thin film bulk acoustic wave filter with two pairs of electrodes symmetrically deposited on the center of the zinc oxide film. The two-dimensional scalar differential equations which were first derived to describe in-plane vibration distribution by Tiersten and Stevens are employed. The Ritz method with trigonometric functions as basis functions is used based on a variational formulation developed in our previous paper. Free vibration resonant frequencies and corresponding modes are obtained. The modes may separate into symmetric and antisymmetric ones for such a structurally symmetric filter. Trapped modes with vibrations mainly under the driving electrodes are exhibited. The six corner-type regions of the filter neglected by Tiersten and Stevens for an approximation are taken into account in our analysis. Results show that their approximation can lead to an inaccuracy on the order of dozens of ppm for the fundamental mode, which is quite significant in filter operation and application.

Theory, For Instance

DEFF Research Database (Denmark)

Balle, Søren Hattesen

This paper takes its starting point in a short poem by Wallace Stevens from 1917, which incidentally bears the title “Theory”. The poem can be read as a parable of theory, i.e., as something literally ’thrown beside’ theory (cf. OED: “...“). In the philosophical tradition this is also how the style of theory has been figured, that is to say: as something that is incidental to it or just happens to be around as so much paraphernalia. In my reading of Stevens’ poem I shall argue that this is exactly the position from which Stevens takes off when he assumes...... the task of writing a personified portrait of theory. Theory emerges as always beside(s) itself in what constitutes its style, but the poem also suggests that theory’s style is what gives theory both its power and its contingency. Figured as a duchess Theoria is only capable of retaining her power...

Stormy Waters: Technology, Sea Control and Regional Warfare

Science.gov (United States)

1994-06-01

planning models. The resulting hybrid model consists of an analysis of the strengths and weaknesses within an organization ( SWOT analysis) and the...34Deterrence Theory Revisited." World Politics 31 (10 August 1979): 289-324. Jones , Rodney W. and Steven A. Hildreth. Modern Weapons and Third World Powers

Browse Title Index

African Journals Online (AJOL)

Items 1 - 50 of 108 ... Paul Tiyambe Zeleza. Vol 2004, No 1 (2004), Africanity: \\'The (Third) World as a Ghetto\\'?: Looking for A Third Space Between \\'Postmodern\\' Cosmopolitanism and Cultural Nationalism, Abstract. Steven Robins. Vol 1999, No 3-4 (1999), Alien-Nation: Zombies, Immigrants and Millennial Capitalism, Details.

76 FR 56191 - Notice of Application; ANR Pipeline Company

Science.gov (United States)

2011-09-12

... Project (MRP), comprised of a new 6,300 horsepower compressor station in Portage County, Wisconsin, all as... TTY, (202) 502-8659. Located in Portage County, Wisconsin, north of Stevens Point, Wisconsin, the MRP... service commitments of ANR's shippers in Wisconsin. ANR states that the MRP will increase the reliability...

South African Medical Journal - Vol 90, No 11 (2000)

African Journals Online (AJOL)

Empiric treatment based on Helicobacter Pylori serology cannont substitute for early endoscopy in the management of dyspeptic rural black africans · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Stephen JD O'Keefe, B Salvador, J Nainkin, S Majiki, H Stevens, ...

Darwin and Teacher: An Analysis of the Mentorship between Charles Darwin and Professor John Henslow.

Science.gov (United States)

McGreevy, Ann

1990-01-01

The paper examines the mentorship between Charles Darwin and his teacher, John Stevens Henslow of Cambridge University (England). The importance of a mentor in stimulating creative productivity is demonstrated through discussion of their teaching and learning styles, their interests, their time spent together, and Henslow's character traits.…

The Evil that Americans Did

Science.gov (United States)

Smith, John David

2007-01-01

Slavery's unequivocal evil lies at the heart of debates over apologizing for America's "peculiar institution" and awarding reparations. In The Problem of Evil: Slavery, Freedom, and the Ambiguities of American Reform, a provocative collection of original essays, the editors Steven Mintz and John Stauffer, along with 23 contributors,…

76 FR 47645 - CSX Transportation, Inc.-Trackage Rights Exemption-Norfolk Southern Railway Company

Science.gov (United States)

2011-08-05

... Crossing Agreement and replace the current crossing diamond with a turnout and switches lining CSXT's spur into NSR's spur north of Craven's Yard. CSXT states that, by retiring the crossing diamond, the parties... served on Steven C. Armbrust, Esq., CSX Transportation, Inc., 500 Water Street J-150, Jacksonville, FL...

77 FR 60741 - Convening of an Accountability Review Board To Examine the Circumstances Surrounding the Deaths...

Science.gov (United States)

2012-10-04

... Hillary Rodham Clinton has determined that the recent deaths of Ambassador J. Christopher Stevens..., Libya involved loss of life at or related to a U.S. mission abroad. Therefore, Secretary Clinton has... cooperation. The Board will submit its conclusions and recommendations to Secretary Clinton within 60 days of...

77 FR 15973 - Fisheries Off West Coast States; Highly Migratory Species Fisheries; Swordfish Retention Limits

Science.gov (United States)

2012-03-19

... Magnuson-Stevens Fishery Conservation and Management Act (MSA) to modify retention limits for swordfish... (RFA). Based on the average observed annual catches by this vessel and the market values for that catch... due to this comment. The second critical comment, submitted on behalf of the Turtle Island Restoration...

The Impact of iPad Multimodalities on the Literacy Skills of Adolescent Males Identified as Low-Achieving Readers

Science.gov (United States)

Pacheco, Beatriz

2017-01-01

Literacy rates among male adolescents continue to fall below those of female adolescents, and this trend shows no indication of improving (Cheung & Slavin, 2014; Gurian & Stevens, 2007; Weins, 2005; Clark, 2006; Cantrell & Carter, 2009). This study aims to examine this trend by measuring the effects of extended literacy learning…

Spielberg varastas Hitchcocki tagant?

Index Scriptorium Estoniae

2008-01-01

Filmiprodutsent Sheldon Abendi pärijad nõuavad Steven Spielbergilt, tootjatelt DreamWorks ja Paramount Pictures kahjutasu filmi "Disturbia" linastamise eest, kuna see kopeerivat Cornell Woodrichi lühijuttu, mille järgi tegi A. Hitchcock filmi "Rear Window" ning mille autoriõigused kuuluvad S. Abendi pärijatele

Cyberporn: Protecting Our Children from the Back Alleys of the Internet. Joint Hearing before the Subcommittee on Basic Research and the Subcommittee on Technology of the Committee on Science. House of Representatives, One Hundred Fourth Congress, First Session.

Science.gov (United States)

Congress of the U.S., Washington, DC. House Committee on Science.

This document presents witness testimony and supplemental materials from a Congressional hearing called to address concerns about the Internet becoming a forum through which minors can be exposed to pornographic or otherwise offensive material. It features opening statements by Congressman Steven H. Schiff, chairman of the House Subcommittee on…

The Soviet Air Force and Strategic Bombing

Science.gov (United States)

1999-04-01

to envision a British Air Force that could be totally divorced from some form of ground support role. Consequently, he saw an air campaign that would...CA: Presidio Press, 1986. Black, Steven K. The Icarus Illusion: Technology, Doctrine and the Soviet Air Force. Monterrey , CA, 1986. Cockburn, Andrew

50 CFR 600.120 - Employment practices.

Science.gov (United States)

2010-10-01

... funded in lieu of life and medical/dental policies are not permitted. (d) Unused sick leave may be... ADMINISTRATION, DEPARTMENT OF COMMERCE MAGNUSON-STEVENS ACT PROVISIONS Regional Fishery Management Councils § 600.120 Employment practices. (a) Council staff positions must be filled solely on the basis of merit...

Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (83rd, Phoenix, Arizona, August 9-12, 2000). Miscellaneous, Part III.

Science.gov (United States)

Association for Education in Journalism and Mass Communication.

The Miscellaneous, part III section of the proceedings contains the following 11 papers: "The Relationship between Health and Fitness Magazine Reading and Eating-Disordered Weight-Loss Methods among High School Girls" (Steven R. Thomsen, Michelle M. Weber, and Lora Beth Brown); "A Practical Exercise for Teaching Ethical Decision…

'Volstrekt realistische situaties in computergames? Die hebben we thuis al' (Review)

NARCIS (Netherlands)

Dormans, Joris

2014-01-01

abstractIn this critical overview four recent studies of computer games are discussed and compared. First, Steven L. Kent's The Ultimate History of Videogames (2001), which gives an insight into the daily practice of the video gaming industry and all that is linked to it. In Rusel DeMaria &

78 FR 57163 - Agency Information Collection Activities: Proposed Collection; Comment Request

Science.gov (United States)

2013-09-17

.... You may mail written comments to the following address: CMS, Office of Strategic Operations and... Under the PRA (44 U.S.C. 3501-3520), federal agencies must obtain approval from the Office of Management... Steven Johnson at 410-786-3332). Dated: September 11, 2013. Martique Jones, Deputy Director, Regulations...

50 CFR 600.425 - Release of statistics.

Science.gov (United States)

2010-10-01

... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Release of statistics. 600.425 Section 600... ADMINISTRATION, DEPARTMENT OF COMMERCE MAGNUSON-STEVENS ACT PROVISIONS Confidentiality of Statistics § 600.425 Release of statistics. (a) The Assistant Administrator will not release to the public any statistics...

50 CFR 600.415 - Access to statistics.

Science.gov (United States)

2010-10-01

... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Access to statistics. 600.415 Section 600... ADMINISTRATION, DEPARTMENT OF COMMERCE MAGNUSON-STEVENS ACT PROVISIONS Confidentiality of Statistics § 600.415 Access to statistics. (a) General. In determining whether to grant a request for access to confidential...

"Tehisintellekti" pikk tee ekraanile

Index Scriptorium Estoniae

2001-01-01

Mängufilmi "A.I. - Tehisintellekt" ("A.I. : Artificial Intelligence") ekraanile seadmise mõte sündis režissöör Stanley Kubrick'il 1969. aastal, kui ilmus Brian Aldissi ulmejutt "Supertoys Last All Summer Long". Ekraanile jõudis see 2001. a. Steven Spielbergi käe all

2485-IJBCS-Article-Dr Zinsou Valerien

African Journals Online (AJOL)

hp

Thowthampitak J. 2008. RpfF gene of. Xanthomonas axonopodis pv. glycines involved in the regulation of virulence factor production and epiphytic fitness of bacterial pustule pathogen on soybean leaves. PhD thesis, Kasetsart. University, p. 139. Wrather JA, Sleper DA, Stevens WE,. Shannon JG, Wilson RF. 2003. Planting.

Behind the Mosaic: Insurgent Centers of Gravity and Counterinsurgency

Science.gov (United States)

2011-12-01

Clausewitz (London, United Kingdom: Pimlico, 2002), 47. 61Mao, 79. 62An illustrative list includes Vietnam, Thailand, Philippines, Sri Lanka, and Peru ...2004. ———. The Tet Offensive: A Concise History. New York: Columbia University Press, 2007. Wright, Donald P., James R. Bird, Steven E. Clay , Peter

78 FR 15929 - Agency Information Collection Activities: Proposed Collection; Comment Request-Impact of...

Science.gov (United States)

2013-03-13

... the use of administrative data in six States and a qualitative research component involving on-site... may be sent to: Steven Carlson, Office of Research and Analysis, Food and Nutrition Service, U.S... research consisting of rigorous case studies in selected States and analyses of emerging national survey...

78 FR 28881 - Changes in Flood Hazard Determinations

Science.gov (United States)

2013-05-16

..., 83843. ID 83843. Illinois: Cook (FEMA Docket No.: B-1280) Village of Bridgeview The Honorable Steven... 46373. Lake (FEMA Docket No.: B-1295) City of Hammond (12- The Honorable Thomas 5925 Calumet Avenue.... Cuyahoga (FEMA Docket No.: B- City of Strongsville The Honorable Thomas 16099 Foltz Industrial December 7...

Assessing Community Needs for Expanding Environmental Education Programming

Science.gov (United States)

Hintz, Carly J.; Lackey, Brenda K.

2017-01-01

Based on increased demand for educational programming, leadership at Schmeeckle Reserve, a campus natural area in Stevens Point, WI explored the needs for expanded environmental education efforts. In 2014, a three-phased needs assessment framework was employed to explore educational programming offered in the community. Results from interviews and…

76 FR 58277 - Performance Review Board Members

Science.gov (United States)

2011-09-20

.... Cantrell, Patrick H. Conway, Kathleen M. Crosby, John Czajkowski, Cheryl R. Dammons, Michelle S. Davis..., William B. Schultz, Neil Shapiro, Jeremy B. Sharp, George H. Sheldon, Steven D. Silverman, Rebecca T... E. Tyler Jr., Stephen J. Veneruso, Karen V. Walker Bryce, Luis A. Wilmot, Holly J. Wong, Robert K...

75 FR 68317 - Agency Information Collection Activities: Proposed Collection; Comment Request-Evaluation of the...

Science.gov (United States)

2010-11-05

... Research and Analysis, Food and Nutrition Service, U.S. Department of Agriculture, 3101 Park Center Drive, Room 1014, Alexandria, VA 22302. Comments may also be submitted via fax to the attention of Steven... free or reduced-price school meals will be divided into treatment and control groups. Affected Public...

A Direction Finding System for Transient Signals

Science.gov (United States)

2007-03-01

WHEN NO LONGER NEEDED. DO NOT RETURN IT TO THE ORIGINATOR. ERDC/CERL SR-07-3 iii Preface This technology is under development with funding from... enlight - ening discussions on this topic with Professor Steven J. Franke. 3 REPORT DOCUMENTATION PAGE Form Approved OMB No. 0704-0188 Public

Opening Philosophy to the World: Derrida and Education in Philosophy

Science.gov (United States)

Burik, Steven

2009-01-01

In this essay, Steven Burik discusses Jacques Derrida's position with regard to the place of education in philosophy within the university system, and then relates these thoughts to comparative philosophy. Philosophers find themselves constantly having to defend philosophy and the importance of teaching philosophy against pressure from the powers…

75 FR 12462 - Fisheries of the Northeastern United States; Northeast Multispecies Fishery; Removal of Gear...

Science.gov (United States)

2010-03-16

...; Removal of Gear Restriction for the U.S./Canada Management Area AGENCY: National Marine Fisheries Service...; removal of gear restrictions. SUMMARY: This action removes temporary gear restrictions in both the Eastern... Management Act (Magnuson- Stevens Act). DATES: Removal of the temporary gear restriction in the Western U.S...

Translingual Paratopia and the Universe of Katalin Molnar

Science.gov (United States)

Ori, Julia

2015-01-01

The concept of paratopia in Dominique Maingueneau's literary discourse analysis designates the writers' paradoxical location, their oscillation between belonging and not belonging to the literary field and to the society. This in-between situation is also characteristic to bilingual people, and as such translingual writers (Steven Kellman,…

Census Report: Volume V, 1986. Sanitized Version.

Science.gov (United States)

1991-04-01

0. 0599 OWAIS, MUHAMMAD 0954 OWEN, STEVEN R. 0916 OWENS, CLINT G. 0599 OWENS, GREGORY 0599 OWENS, RUSSELL E. 0837 OZDEMIR, LEVENT 0916 PACHECO, ERNEST...ORG NAME CODE SUSHINSKI, THOMAS C. 0916 SUTHERLAND , DEAN R. 0837 SVADBA, KEITH A. 0599 SVOBODA, THOMAS R. 0637 SWAIN, JEFFREY MANNING 0916 SWAIN

77 FR 9198 - Agency Information Collection Activities: Proposed Collection; Comments Request-Study of...

Science.gov (United States)

2012-02-16

... administer farmers' market SNAP incentives. The interview is designed to gather qualitative data to better... other forms of information technology. Comments may be sent to: Steven Carlson, Office of Research and... electronically. All written comments will be open for public inspection at the Office of Research and Analysis...

78 FR 29116 - North Pacific Fishery Management Council; Public Meeting

Science.gov (United States)

2013-05-17

... BOF state water groundfish fishery proposals; Update on definition of a fishing guide and coordination....noaa.gov/npfmc/ . Although non-emergency issues not contained in this agenda may come before this group... publication of this notice that require emergency action under section 305(c) of the Magnuson-Stevens Fishery...

Collection Development and Circulation Policies in Prison Libraries: An Exploratory Survey of Librarians in US Correctional Institutions

Science.gov (United States)

Conrad, Suzanna

2012-01-01

Prison libraries have traditionally fulfilled many purposes for their incarcerated patrons, and these libraries often carry a diverse collection to serve varied patron needs. However, during the trial of Steven Hayes for the Petit family murders, the prosecution questioned the collection development policies of the institutions where Hayes had…

Episodic intrusion, internal differentiation, and hydrothermal alteration of the miocene tatoosh intrusive suite south of Mount Rainier, Washington

Science.gov (United States)

du Bray, E.A.; Bacon, C.R.; John, D.A.; Wooden, J.L.; Mazdab, F.K.

2011-01-01

The Miocene Tatoosh intrusive suite south of Mount Rainier is composed of three broadly granodioritic plutons that are manifestations of ancestral Cascades arc magmatism. Tatoosh intrusive suite plutons have individually diagnostic characteristics, including texture, mineralogy, and geochemistry, and apparently lack internal contacts. New ion-microprobe U-Pb zircon ages indicate crystallization of the Stevens pluton ca. 19.2 Ma, Reflection-Pyramid pluton ca. 18.5 Ma, and Nisqually pluton ca. 17.5 Ma. The Stevens pluton includes rare, statistically distinct ca. 20.1 Ma zircon antecrysts. Wide-ranging zircon rare earth element (REE), Hf, U, and Th concentrations suggest late crystallization from variably evolved residual liquids. Zircon Eu/Eu*-Hf covariation is distinct for each of the Reflection-Pyramid, Nisqually, and Stevens plutons. Although most Tatoosh intrusive suite rocks have been affected by weak hydrothermal alteration, and sparse mineralized veins cut some of these rocks, significant base or precious metal mineralization is absent. At the time of shallow emplacement, each of these magma bodies was largely homogeneous in bulk composition and petrographic features, but, prior to final solidification, each of the Tatoosh intrusive suite plutons developed internal compositional variation. Geochemical and petrographic trends within each pluton are most consistent with differential loss of residual melt, possibly represented by late aplite dikes or erupted as rhyolite, from crystal-rich magma. Crystal-rich magma that formed each pluton evidently accumulated in reservoirs below the present level of exposure and then intruded to a shallow depth. Assembled by episodic intrusion, the Tatoosh intrusive suite may be representative of midsized composite plutonic complexes beneath arc volcanoes. ?? 2011 Geological Society of America.

Cultural Adaptation of a Neurobiologically Informed Intervention in Local and International Contexts

Science.gov (United States)

Pakulak, Eric; Hampton Wray, Amanda; Longoria, Zayra; Garcia Isaza, Alejandra; Stevens, Courtney; Bell, Theodore; Burlingame, Sarah; Klein, Scott; Berlinski, Samuel; Attanasio, Orazio; Neville, Helen

2017-01-01

The relationship between early adversity and numerous negative outcomes across the lifespan is evident in a wide range of societies and cultures (e.g., Pakulak, Stevens, & Neville, 2018). Among the most affected neural systems are those supporting attention, self-regulation, and stress regulation. As such, these systems represent targets for…

Julgus kahelda / Andres Kurg

Index Scriptorium Estoniae

Kurg, Andres, 1975-

2004-01-01

Okupatsioonide muuseumist, 7. "Europani" arhitektuurikonkursil äramärgitud tööst "Alvar" (autoreiks Londonis töötavad arhitektid Eike Sindlinger, Ulrike Steven, Gareth Morris büroost 7-degrees), mis püüab positiivselt sekkuda Tallinna Lasnamäe praegusesse hoonestusse, võimalustest teha sotsiaalselt tundlikku arhitektuuri

77 FR 68886 - Aiken Railway Company, LLC-Lease and Operation Exemption-Lines of Norfolk Southern Railway...

Science.gov (United States)

2012-11-16

... Carolina Railway Service Corporation (WCRS), and Steven C. Hawkins and Cheryl R. Hawkins (collectively, the Hawkins) seek Board approval to continue in control of AIKR upon AIKR's becoming a Class III rail carrier... 5, 2012. WCRS and the Hawkins are reminded that they are not authorized to control AIKR until the...

77 FR 32408 - Fisheries of the Caribbean, Gulf of Mexico, and South Atlantic; Snapper-Grouper Fishery Off the...

Science.gov (United States)

2012-06-01

..., Magnuson-Stevens Act requirements, the social and economic environment, and trends in effort which are... landings reach the appropriate level to trigger the AMs. Comment 15: Two recreational anglers state that... brought to shore each day is not necessary to reduce the risk of right whale interactions with black sea...

On the Integration of Medium Wave Infrared Cameras for Vision-Based Navigation

Science.gov (United States)

2015-03-01

almost negligible detection by EO cameras in the dark . In order to compare the estimated SfM trajectories, the point clouds created by VisualSFM for...IEEE, 2000. [14] Noah Snavely, Steven M Seitz, and Richard Szeliski. Photo tourism : exploring photo collections in 3d. In ACM transactions on graphics

50 CFR 648.55 - Framework adjustments to management measures.

Science.gov (United States)

2010-10-01

... prevent overfishing on a continuing basis, as required by National Standard 1 of the Magnuson-Stevens Act... expected to achieve OY and prevent overfishing on a continuing basis, the PDT shall recommend to the... overfishing on a continuing basis. When making the status determination in the SAFE Report, the PDT shall...

76 FR 13887 - Fisheries of the Northeastern United States; Atlantic Mackerel, Squid, and Butterfish (MSB...

Science.gov (United States)

2011-03-15

...). This emergency action increases the butterfish allowable biological catch (ABC) for the 2011 fishing... CONTACT: Aja Peters-Mason, Fishery Policy Analyst, (978) 281-9195, fax (978) 281-9135. SUPPLEMENTARY... Magnuson-Stevens Act, to increase the butterfish ABC for the 2011 fishing year (FY) from 1,500 mt to 1,811...

Development of a Physiologically-Based Pharmacokinetic Model of Trichloroethylene and Its Metabolites for Use in Risk Assessment

Science.gov (United States)

2004-09-01

and free trichloroethanol. Toxicol. App!. Pharmacol., 152, 339-359, 1998. 10. Stenner , R.D., Merdink, J.L., Fisher, J.W., and Bull, R...M.V., Stevens, D.K., Stenner , R.D., Bonate, P.L., Tuman, D., and Bull, R.J., Factors affecting species differences in the kinetics of metabolites of

Effect of Cedrus deodara (Pinaceae) Root Oil on the Histopathology ...

African Journals Online (AJOL)

Treated and untreated group of rats were sacrificed and organs (liver and kidney) were taken out for tissue processing and staining with haematoxylin and eosin according to the method of Bancroft and Stevens. Microscopic examination was then carried out to observe any pathological changes in the animals. Results: The ...