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Sample records for sammons rebecca smees

  1. The South China Sea Mesoscale Eddy Experiment (S-MEE) and Its Primary Findings

    Science.gov (United States)

    Zhang, Z.; Tian, J.; Zhao, W.; Qiu, B.

    2016-02-01

    South China Sea (SCS), the largest marginal sea in the northwestern Pacific, have strong eddy activities as revealed by both satellite and in situ observations. The 3D structures of the SCS mesoscale eddies and their lifecycles, including the generation and dissipation processes, are, however, still not well understood at present because of the lack of well-designed field observations. In order to address the above two scientific issues (3D structure and lifecycle of SCS mesoscale eddies), the SCS Mesoscale Eddy Experiment (S-MEE for short) was designed and conducted in the period from October 2013 to June 2014. As part of S-MEE, two bottom-anchored subsurface mooring arrays with one consisting of 10 moorings and the other 7 moorings, were deployed along the historical pathway of the mesoscale eddies in the northern SCS. All the moorings were equipped with ADCPs, RCMs, CTDs and temperature chains to make continues measurements of horizontal current velocity and temperature/salinity in the whole water column. During the S-MEE, a total of 5 distinct mesoscale eddies were observed to cross the mooring arrays, among which one anticyclonic and cyclonic eddy pair was fully captured by the mooring arrays. In addition to moored observations, we also conducted two transects across the center of the anticyclonic eddy and made high-resolution hydrographic and turbulent mixing measurements. Based on the data collected by the S-MEE and concurrent satellite-derived observations, we constructed the full-depth 3D structure of the eddy pair and analyzed its generation and dissipation mechanisms. We found that the eddies extend from the surface to the sea bottom and display prominent tilted structures in the vertical. By conducting an eddy energy budget analysis, we further identified that generation of submesoscale motions constitutes the dominant mechanism for the oceanic eddy dissipation.

  2. Rebecca sõidabki Kiievisse / Silja Joon

    Index Scriptorium Estoniae

    Joon, Silja, 1966-

    2005-01-01

    Eesti Televisiooni stuudiotes toimunud Eurovisiooni rahvusliku eelvooru "Eurolaul 2005" võitnud laulust "Let's Get Loud" (autor Sven Lõhmus), esitajast ansamblist Suntribe, lauljast Rebecca Kontusest. Laulude edetabel

  3. Tips From Former Smokers - Rebecca

    Centers for Disease Control (CDC) Podcasts

    2016-01-20

    Rebecca struggled with depression for years. She also smoked. Finally, she realized that smoking wasn’t helping her, so she got care for her depression and quit for good.  Created: 1/20/2016 by Office on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion.   Date Released: 1/20/2016.

  4. Rebecca Kontus püüab eurolaulu võitu / Evelin Nõmmik

    Index Scriptorium Estoniae

    Nõmmik, Evelin

    2005-01-01

    Eurovisiooni rahvusliku eelvooru "Eurolaul 2005" finaalist ETV kanalil 5. veebr., lauljast Rebecca Kontusest lauludega "Have You Ever" ja "Let's Get Loud" (viimane ansambli Suntribe koosseisus), nimekiri võistluse lauludest

  5. Mentors Coaching Principals in Instructional Leadership: The Case of Rebecca and Ramon

    Science.gov (United States)

    Carver, Cynthia L.

    2010-01-01

    This case is told from the perspective of Rebecca, a highly skilled mentor teacher, who struggles to work effectively with Ramon, the school principal. This case focuses on the supports and resources that instructional teacher leaders can provide to their school administrators. As the case suggests, the presence of well-trained mentors presents…

  6. (Re)Mapping the Colonized Body: The Creative Interventions of Rebecca Belmore in the Cityscape

    Science.gov (United States)

    Nagam, Julie

    2011-01-01

    The cityscape holds the memories of indigenous bones and bodies that resurrect a deep sense of place that exists in the landscape of the city of Toronto. This deep sense of place is part of a connection to the land and stories of place. In this article, the author bridges the creative work of Anishinaabe artist Rebecca Belmore with the living…

  7. Patriarchal hauntings : re-reading villainy and gender in Daphne du Maurier's 'Rebecca'

    OpenAIRE

    Llompart Pons, Auba

    2015-01-01

    Daphne du Maurier's popular classic Rebecca (1938) was traditionally marketed as a Gothic romance in which two lovers conquered the evil women that separated them. In more recent years, some feminist critics have provided a very different view of the story as a Gothic narrative about the dangers women suffer under patriarchal control. In this thesis, I propose, through a Gothic Studies and a Gender Studies reading, that the victim/abuser statuses in du Maurier's novel cannot be equated to fem...

  8. Caught Up In Between Doublets: Neo-Victorian (TransPositions of Victorian Femininities and Masculinities in Jane Eyre and Rebecca Entre les doublets : (transpositions néo-victoriennes des figures victoriennes de la féminité et de la masculinité dans Jane Eyre et Rebecca

    Directory of Open Access Journals (Sweden)

    Marta Miquel-Baldellou

    2009-07-01

    Full Text Available En se départissant de la dichotomie victorienne manichéenne de l’ange du foyer et de la femme déchue pour éclairer les personnages de Jane et Bertha dans leur ouvrage pionnier The Madwoman in the Attic, Sandra Gilbert et Susan Gubar étudièrent la première épouse de Rochester, folle, comme le double subversif de Jane, faisant ainsi de Jane et de Bertha les facettes d’un seul et même personnage. Malgré le rejet moderniste des excès supposés de l’ère victorienne, Rebecca de Daphne du Maurier exploite une intrigue triangulaire similaire qui réinterprète et recrée Rochester, Bertha et Jane à travers Maxime de Winter, Rebecca et Mrs de Winter. Les conceptions victoriennes des féminités doubles, des doublets féminins pour ainsi dire, sont perpétuées et réactualisées à travers les textualités néo-victoriennes. Néanmoins, peut-on vraiment voir dans Bertha un personnage que Rochester tente d’assagir par l’entremise de la figure de l’ange du foyer, plutôt qu’un archétype de la femme déchue ? Jane n’est-elle pas destinée à découvrir le secret de Rochester avant de l’épouser ? Mrs de Winter a-t-elle à ce point le sens du sacré qu’elle ne cherche pas à entrer en concurrence avec Rebecca ? Rebecca est-elle à ce point élégante et infaillible qu’elle parvient à ne pas s’attirer le mépris de Maxime ? Cet article se propose d’examiner comment les héroïnes sont investies en termes de rôles sexuels dans l’écriture néo-victorienne – comment les rôles de l’ange du foyer et de la femme déchue dans Jane Eyre sont perpétués et subvertis à travers Rebecca en tant que texte moderne – et d’identifier et d’étudier les perceptions masculines victoriennes et néo-victoriennes.

  9. Researcher Profile: An Interview With Dr. Rebecca J. Travnichek

    Directory of Open Access Journals (Sweden)

    Rebecca J. Travnichek

    2011-04-01

    Full Text Available

    Dr. Rebecca Travnichek is a Family Financial Education Specialist with University of Missouri Extension. Dr. Travnichek currently serves as the Annual Conference Program Chair. She is also very active in the Association for Financial Counseling and Planning Education, where she serves on the Board of Directors. Dr. Travnichek has participated in leadership development programs at the state and national levels. She was involved in the initial proposal development of the Financial Security for All Community of Practice with eXtension and continues to be involved through several roles. She is active in the National Extension Association of Family and Consumer Sciences at the national and state levels, serving in multiple leadership roles. For the past three years, Dr. Travnichek has also served as the Editor of the Journal of the National Extension Association of Family and Consumer Sciences. She represents the type of person who makes the Financial Therapy Association a dynamic organization linking practitioners and academicians.

  10. The Psychometric Analysis of the Persian Version of the Strategy Inventory for Language Learning of Rebecca L. Oxford

    Science.gov (United States)

    Fazeli, Seyed Hossein

    2012-01-01

    The current study aims to analyze the psychometric qualities of the Persian adapted version of Strategy Inventory for Language Learning (SILL) developed by Rebecca L. Oxford (1990). Three instruments were used: Persian adapted version of SILL, a Background Questionnaire, and Test of English as a Foreign Language. Two hundred and thirteen Iranian…

  11. MANUSIA DAN LINGKUNGAN DALAM NOVEL LIFE IN THE IRON MILLS KARYA REBECCA HARDINGS DAVIS

    Directory of Open Access Journals (Sweden)

    Juliasih K

    2013-01-01

    Full Text Available This study aims to investigate the possibilities of alleviating the damage of the environment as a result of industrialization driven by the capitalist system as seen in Life in the Iron Mills, a novella by Rebecca Harding Davis. This study applied ecocriticism which succinctly might be defined as study of the relation between literature and environment conducted in a commitment to environmental praxis. The findings show that there should be the actions of moral principles as a consideration in social policies, politics, and economy. The principles include respect, responsibility, love and care, simplicity, and justice. These actions allow changes from the material-oriented lifestyle to the simple lifestyle and are done by an individual or community to encourage the reform. Everybody should jointly and actively practice the environmental ethics.

  12. Pupil Response and the Subliminal Mere Exposure Effect

    Science.gov (United States)

    Yoshimoto, Sanae; Imai, Hisato; Kashino, Makio; Takeuchi, Tatsuto

    2014-01-01

    The subliminal mere exposure effect (SMEE) is the phenomenon wherein people tend to prefer patterns they have repeatedly observed without consciously identifying them. One popular explanation for the SMEE is that perceptual fluency within exposed patterns is misattributed to a feeling of preference for those patterns. Assuming that perceptual fluency is negatively correlated with the amount of mental effort needed to analyze perceptual aspects of incoming stimuli, pupil diameter should associate with SMEE strength since the former is known to reflect mental effort. To examine this hypothesis, we measured participants’ pupil diameter during exposure to subthreshold stimuli. Following exposure, a preference test was administered. Average pupil diameter throughout exposure was smaller when the SMEE was induced than when the SMEE was not induced. This supports the hypothesis that increasing perceptual fluency during mere exposure modulates autonomic nervous responses, such as pupil diameter, and eventually leads to preference. PMID:24587408

  13. Pupil response and the subliminal mere exposure effect.

    Science.gov (United States)

    Yoshimoto, Sanae; Imai, Hisato; Kashino, Makio; Takeuchi, Tatsuto

    2014-01-01

    The subliminal mere exposure effect (SMEE) is the phenomenon wherein people tend to prefer patterns they have repeatedly observed without consciously identifying them. One popular explanation for the SMEE is that perceptual fluency within exposed patterns is misattributed to a feeling of preference for those patterns. Assuming that perceptual fluency is negatively correlated with the amount of mental effort needed to analyze perceptual aspects of incoming stimuli, pupil diameter should associate with SMEE strength since the former is known to reflect mental effort. To examine this hypothesis, we measured participants' pupil diameter during exposure to subthreshold stimuli. Following exposure, a preference test was administered. Average pupil diameter throughout exposure was smaller when the SMEE was induced than when the SMEE was not induced. This supports the hypothesis that increasing perceptual fluency during mere exposure modulates autonomic nervous responses, such as pupil diameter, and eventually leads to preference.

  14. Pupil response and the subliminal mere exposure effect.

    Directory of Open Access Journals (Sweden)

    Sanae Yoshimoto

    Full Text Available The subliminal mere exposure effect (SMEE is the phenomenon wherein people tend to prefer patterns they have repeatedly observed without consciously identifying them. One popular explanation for the SMEE is that perceptual fluency within exposed patterns is misattributed to a feeling of preference for those patterns. Assuming that perceptual fluency is negatively correlated with the amount of mental effort needed to analyze perceptual aspects of incoming stimuli, pupil diameter should associate with SMEE strength since the former is known to reflect mental effort. To examine this hypothesis, we measured participants' pupil diameter during exposure to subthreshold stimuli. Following exposure, a preference test was administered. Average pupil diameter throughout exposure was smaller when the SMEE was induced than when the SMEE was not induced. This supports the hypothesis that increasing perceptual fluency during mere exposure modulates autonomic nervous responses, such as pupil diameter, and eventually leads to preference.

  15. Simultaneous Determination of Four Tanshinones by UPLC-TQ/MS and Their Pharmacokinetic Application after Administration of Single Ethanol Extract of Danshen Combined with Water Extract in Normal and Adenine-Induced Chronic Renal Failure Rats

    Directory of Open Access Journals (Sweden)

    Hong-Die Cai

    2016-11-01

    Full Text Available Salvia miltiorrhiza, one of the major traditional Chinese medicines, is commonly used and the main active ingredients—tanshinones—possess the ability to improve renal function. In this paper, the UPLC-TQ/MS method of simultaneously determining four tanshinones—tanshinone IIA, dihydrotanshinone I, tanshinone I, and cryptotanshinone—was established and applied to assess the pharmacokinetics in normal and chronic renal failure (CRF rat plasma. The pharmacokinetics of tanshinones in rats were studied after separately intragastric administration of Salvia miltiorrhiza ethanol extract (SMEE (0.65 g/kg, SMEE (0.65 g/kg combined with Salvia miltiorrhiza water extract (SMWE (1.55 g/kg. The results showed Cmax and AUC0–t of tanshinone IIA, tanshinone I, cryptotanshinone reduced by 50%~80% and CLz/F increased by 2~4 times (p < 0.05 in model group after administrated with SMEE. Nevertheless, after intragastric administration of a combination of SMWE and SMEE, the Cmax and AUC0–t of four tanshinones were upregulated and CLz/F was downregulated, which undulated similarity from the model group to the normal group with compatibility of SMEE and SMWE. These results hinted that SMWE could improve the bioavailability of tanshinones in CRF rats, which provides scientific information for further exploration the mechanism of the combination of SMWE and SMEE and offers a reference for clinical administration of Salvia miltiorrhiza.

  16. Beginning with the Body: Fleshy Politics in the Performance Art of Rebecca Belmore and Leah Lakshmi Piepzna-Samarasinha

    Directory of Open Access Journals (Sweden)

    Samantha Balzer

    2014-06-01

    Full Text Available This article examines what I term the "fleshy" politics of Rebecca Belmore's 2002 Vigil and Leah Lakshmi Piepzna-Samarasinha's contributions to the 2009 version of the performance project Sins Invalid: An Unshamed Claim to Beauty in the Face of Invisibility. Focusing on the embodied performances of both Belmore and Piepzna-Samarasinha, I read the skin of the artist as a site where complex politics develop. This analysis is broken into three sections: the first considers the relationship between the performing body and the performance space; the second attends to specific movements each artist makes; the third focuses on garments worn in each piece. Together, I argue, these components of Belmore and Piepzna-Samarasinha's performances contribute to fleshy politics that reimagine the relationship between individuals and community, corporeality and geography, and the present and the past.

  17. Men in (Shell-Shock: Masculinity, Trauma, and Psychoanalysis in Rebecca West's The Return of the Soldier

    Directory of Open Access Journals (Sweden)

    Misha Kavka

    1998-01-01

    Full Text Available This paper undertakes to read Rebecca West's first novel, The Return of the Soldier (1918, as a critical exploration of masculine trauma on the one hand and an ambivalent engagement with Freudian psychoanalysis on the other. The novel proves interesting as a site in which two shifting cultural contexts intersect: the wartime culture of England facing the "shell shock" of its men, and the contemporaneous infusion of English intellectual culture with psychoanalytic ideas. Though the effects of new war technology and "a newer kind of doctor," West challenge existing notions of stable masculinity, West maintains that masculinity has all along been simply a construct, a shell built around inarticulable trauma. The fact that in this novel West, despite her early pugnaciously feminist journalism, remains as much within the masculine order as critical of it forces us to expand our notions of the forms feminist narrative can take. This paper argues that the novel is a feminist narrative in the sense that it positions masculine trauma as a mark of adherence to the social order for both men and women.

  18. Pupil Response and the Subliminal Mere Exposure Effect

    OpenAIRE

    Yoshimoto, Sanae; Imai, Hisato; Kashino, Makio; Takeuchi, Tatsuto

    2014-01-01

    The subliminal mere exposure effect (SMEE) is the phenomenon wherein people tend to prefer patterns they have repeatedly observed without consciously identifying them. One popular explanation for the SMEE is that perceptual fluency within exposed patterns is misattributed to a feeling of preference for those patterns. Assuming that perceptual fluency is negatively correlated with the amount of mental effort needed to analyze perceptual aspects of incoming stimuli, pupil diameter should associ...

  19. In Our Hands: An Ethics of Gestural Response-ability. Rebecca Schneider in conversation with Lucia Ruprecht

    Directory of Open Access Journals (Sweden)

    Rebecca Schneider

    2017-06-01

    Full Text Available The following conversation aims to trace the role of gesture and gestural thinking in Rebecca Schneider’s work, and to tease out the specific gestural ethics which arises in her writings. In particular, Schneider thinks about the politics of citation and reiteration for an ethics of call and response that emerges in the gesture of the hail. Both predicated upon a fundamentally ethical relationality and susceptible to ideological investment, the hail epitomises the operations of the “both/and”—a logic of conjunction that structures and punctuates the history of thinking on gesture from the classic Brechtian tactic in which performance both replays and counters conditions of subjugation to Alexander Weheliye’s reclamation of this tactic for black and critical ethnic studies. The gesture of the hail will lead us, then, to the gesture of protest in the Black Lives Matter movement. The hands that are held up in the air both replay (and respond to the standard pose of surrender in the face of police authority and call for a future that might be different. Schneider’s ethics of response-ability thus rethinks relationality as something that always already anticipates and perpetually reinaugurates possibilities for response.

  20. The relationship between the structural mere exposure effect and the implicit learning process.

    Science.gov (United States)

    Newell, B R; Bright, J E

    2001-11-01

    Three experiments are reported that investigate the relationship between the structural mere exposure effect (SMEE) and implicit learning in an artificial grammar task. Subjects were presented with stimuli generated from a finite-state grammar and were asked to memorize them. In a subsequent test phase subjects were required first to rate how much they liked novel items, and second whether or not they thought items conformed to the rules of the grammar. A small but consistent effect of grammaticality was found on subjects' liking ratings (a "structural mere exposure effect") in all three experiments, but only when encoding and testing conditions were consistent. A change in the surface representation of stimuli between encoding and test (Experiment 1), memorizing fragments of items and being tested on whole items (Experiment 2), and a mismatch of processing operations between encoding and test (Experiment 3) all removed the SMEE. In contrast, the effect of grammaticality on rule judgements remained intact in the face of all three manipulations. It is suggested that rule judgements reflect attempts to explicitly recall information about training items, whereas the SMEE can be explained in terms of an attribution of processing fluency.

  1. Montenegro in Rebecca West’s Black Lamb and Grey Falcon: The literature of travelers as a source for political geogrphy

    Directory of Open Access Journals (Sweden)

    André-Louis Sanguin

    2011-01-01

    Full Text Available The literature of travellers represents a key foundation upon which geography was built as a social construct. It depicts the territorial reality on a personal level. The literature of travellers has been at the origin of popular geographical knowledge. In 1941 the great British novelist Rebecca West (1892-1983 published a chronicle of her travels through Yugoslavia from 1936 to 1938: Black Lamb and Grey Falcon. Her book is a good example and a relevant test of the literature of travellers as a source of political geography. Actually, Black Lamb and Grey Falcon is West’s political response to the Balkans rather than an account of her journey through Yugoslavia. Through her writing, West has contributed to the shape of a different public opinion about Yugoslavia and its peoples which continues to live on. Moreover, her book strongly influenced the Anglo-Saxon policy makers on their comprehension of Yugoslavia. West significantly depicted Montenegro in its history, people, traditions and politics by means of pictures regarding Boka Kotorska, Budva, Cetinje, Kolasin, Mount Lovcen, Plav, and Skadar Lake. On the basis of the chapter devoted to Montenegro in West’s book, the paper will focus on its features of political geography through an analysis of significant geosymbols.

  2. Montenegro in Rebecca West’s Black Lamb and Grey Falcon: The literature of travelers as a source for political geogrphy

    Directory of Open Access Journals (Sweden)

    André-Louis Sanguin

    2011-12-01

    Full Text Available The literature of travellers represents a key foundation upon which geography was built as a social construct. It depicts the territorial reality on a personal level. The literature of travellers has been at the origin of popular geographical knowledge. In 1941 the great British novelist Rebecca West (1892-1983 published a chronicle of her travels through Yugoslavia from 1936 to 1938: Black Lamb and Grey Falcon. Her book is a good example and a relevant test of the literature of travellers as a source of political geography. Actually, Black Lamb and Grey Falcon is West’s political response to the Balkans rather than an account of her journey through Yugoslavia. Through her writing, West has contributed to the shape of a different public opinion about Yugoslavia and its peoples which continues to live on. Moreover, her book strongly influenced the Anglo-Saxon policy makers on their comprehension of Yugoslavia. West significantly depicted Montenegro in its history, people, traditions and politics by means of pictures regarding Boka Kotorska, Budva, Cetinje, Kolasin, Mount Lovcen, Plav, and Skadar Lake. On the basis of the chapter devoted to Montenegro in West’s book, the paper will focus on its features of political geography through an analysis of significant geosymbols.

  3. An eloquent and persuasive Mr. Smee

    Directory of Open Access Journals (Sweden)

    Erio Tosatti

    2006-12-01

    Full Text Available John Ziman with his old-fashioned ways, was a real British gentleman of the colonies. Born and raised in New Zealand, Ziman belonged to that large group of men and women that went back to their fathers’ land in the last century from the Commonwealth countries. In many cases, they were individuals with an outstanding intellect and, therefore, a real tresure trove for Great Britain, which drew from those remote places not only gems, tea, perfumes and raw materials, but also enlightened minds and reliable personalities.

  4. Jane Air: The Heroine as Caged Bird in Charlotte Brontë’s Jane Eyre and Alfred Hitchcock’s Rebecca L’héroïne, oiseau en cage dans Jane Eyre de Charlotte Brontë et Rebecca d’Alfred Hitchcock

    Directory of Open Access Journals (Sweden)

    Paul Marchbanks

    2009-12-01

    Full Text Available Dans le quatrième chapitre de son ouvrage intitulé Brontë Transformations (1996, Patsy Stoneman révèle l’importance des reprises et transformations dont a fait l’objet Jane Eyre (1847 de Charlotte Brontë dans diverses pièces de théâtre, romans et films depuis sa publication initiale. L’un des avatars les plus intéressants mentionné par P. Stoneman est Rebecca d’Alfred Hitchcock (1940 d’après le roman à succès éponyme de Daphné Du Maurier paru en 1938. Parmi les nombreux éléments communs au roman de Brontë et au film d’Hitchcock figurent l’héroïne orpheline consciente de son physique ordinaire, un personnage masculin maussade doté d’une épouse “présente-absente” et une intendante dont le tempérament influence l’atmosphère du manoir dans lequel l’héroïne réside temporairement. Un autre point commun, plus difficile à déceler car profondément intégré à chaque œuvre, est le portrait de l’héroïne en oiseau prisonnier. Ce(tte subtile trope/métaphore mérite d’être remarqué(e car non seulement l’image constitue un lien entre les deux œuvres mais elle permet aussi, dans ses diverses manifestations, de les différencier. Tandis que dans Jane Eyre, l’image de l’oiseau apparaît chaque fois que Jane s’échappe d’un lieu qui l’emprisonne, celle de la cage s’avère être l’élément dominant dans le film d’Hitchcock, imposant finalement des limites infranchissables à la liberté de l’héroïne.

  5. Rebecca Hanes | NREL

    Science.gov (United States)

    the Strategic Energy Analysis Center. Areas of Expertise Mathematical and theoretical aspects of life University, Columbus, OH, 2014 M.S. in applied statistics, The Ohio State University, Columbus, OH, 2013 B.S Multiscale Modeling Framework for Sustainable Process Design Applications." Sustainability of Products

  6. Fikseeritud vahetuskurss ja ujuv vahetuskurss : 1990ndate õppetunnid

    Index Scriptorium Estoniae

    2002-01-01

    Ilmunud ka: Alternative exchange rate regimes in the globalised world : conference dedicated to the 10th anniversary of the re-introduction of the Estonian kroon. - Tallinn. Vestlusringis esinesid Hongkongi Keskpanga tegevjuhi asetäitja Tony Latter, Soome Panga president Matti Vanhala ja Rahvusvahelise Valuutafondi Euroopa II osakonna direktor John Odling-Smee, Euroopa Rekonstruktsiooni- ja Arengupanga peaanalüütik Willem H. Buiter

  7. 77 FR 2076 - National Institute of Mental Health Notice of Closed Meetings

    Science.gov (United States)

    2012-01-13

    ... Conference Call). Contact Person: Rebecca C. Steiner, Ph.D., Scientific Review Officer, Division of... 20037. Contact Person: Rebecca C. Steiner, Ph.D., Scientific Review Officer, Division of Extramural...

  8. An eloquent and persuasive Mr. Smee (Italian original version

    Directory of Open Access Journals (Sweden)

    Erio Tosatti

    2006-12-01

    Full Text Available John Ziman with his old-fashioned ways, was a real British gentleman of the colonies. Born and raised in New Zealand, Ziman belonged to that large group of men and women that went back to their fathers’ land in the last century from the Commonwealth countries. In many cases, they were individuals with an outstanding intellect and, therefore, a real tresure trove for Great Britain, which drew from those remote places not only gems, tea, perfumes and raw materials, but also enlightened minds and reliable personalities.

  9. 76 FR 58285 - National Institute of Mental Health Notice of Closed Meetings

    Science.gov (United States)

    2011-09-20

    ... Pennsylvania Ave., NW., Washington, DC 20037. Contact Person: Rebecca C. Steiner, PhD, Scientific Review...: Rebecca C. Steiner, PhD, Scientific Review Officer, Division of Extramural Activities, National Institute...

  10. Evaluating online data of water quality changes in a pilot drinking water distribution system with multivariate data exploration methods.

    Science.gov (United States)

    Mustonen, Satu M; Tissari, Soile; Huikko, Laura; Kolehmainen, Mikko; Lehtola, Markku J; Hirvonen, Arja

    2008-05-01

    The distribution of drinking water generates soft deposits and biofilms in the pipelines of distribution systems. Disturbances in water distribution can detach these deposits and biofilms and thus deteriorate the water quality. We studied the effects of simulated pressure shocks on the water quality with online analysers. The study was conducted with copper and composite plastic pipelines in a pilot distribution system. The online data gathered during the study was evaluated with Self-Organising Map (SOM) and Sammon's mapping, which are useful methods in exploring large amounts of multivariate data. The objective was to test the usefulness of these methods in pinpointing the abnormal water quality changes in the online data. The pressure shocks increased temporarily the number of particles, turbidity and electrical conductivity. SOM and Sammon's mapping were able to separate these situations from the normal data and thus make those visible. Therefore these methods make it possible to detect abrupt changes in water quality and thus to react rapidly to any disturbances in the system. These methods are useful in developing alert systems and predictive applications connected to online monitoring.

  11. 78 FR 13358 - National Institute of Mental Health; Notice of Closed Meetings

    Science.gov (United States)

    2013-02-27

    ... Washington, DC, 2401 M Street, NW., Washington, DC 20037. Contact Person: Rebecca C Steiner, Ph.D..., (Telephone Conference Call). Contact Person: Rebecca C Steiner, Ph.D., Scientific Review Officer, Division of...

  12. 77 FR 18688 - Safety Zone; Chicago Harbor, Navy Pier Southeast, Chicago, IL

    Science.gov (United States)

    2012-03-28

    ... email MST2 Rebecca Stone, Prevention Department, Coast Guard Sector Lake Michigan, Milwaukee, WI at 414-747-7154, email Rebecca.R.Stone@uscg.mil . SUPPLEMENTARY INFORMATION: The Coast Guard will enforce the...

  13. 77 FR 25361 - Safety Zone; Chicago Harbor, Navy Pier Southeast, Chicago, IL

    Science.gov (United States)

    2012-04-30

    ... email MST2 Rebecca Stone, Prevention Department, Coast Guard Sector Lake Michigan, Milwaukee, WI at 414-747-7154, email Rebecca.R.Stone@uscg.mil . SUPPLEMENTARY INFORMATION: The Coast Guard will enforce the...

  14. Observed 3D Structure, Generation, and Dissipation of Mesoscale Eddies in the South China Sea

    Science.gov (United States)

    Zhang, Z.; Tian, J.; Qiu, B.; Zhao, W.

    2016-12-01

    South China Sea (SCS), the largest marginal sea in the western Pacific, is abundant with strong mesoscale eddies as revealed by both satellite and in situ observations. The 3D structure, generation and dissipation mechanisms of the SCS mesoscale eddies, however, are still not well understood at present due to the lack of well-designed and comprehensive field observations. In order to address the above scientific issues, the SCS Mesoscale Eddy Experiment (S-MEE for short) was designed and conducted in the period from October 2013 to June 2014. As part of S-MEE, two bottom-anchored subsurface mooring arrays with one consisting of 10 moorings and the other 7 moorings, were deployed along the historical pathway of the mesoscale eddies in the northern SCS. All the moorings were equipped with ADCPs, RCMs, CTDs and temperature chains to make continues measurements of horizontal current velocity and temperature/salinity in the whole water column. In addition to moored observations, we also conducted two transects across the center of one anticyclonic eddy (AE) and made high-resolution hydrographic and turbulent mixing measurements. Based on the data collected by the S-MEE, we obtained the full-depth 3D structures of one AE and one cyclonic eddy (CE) and revealed their generation and dissipation mechanisms. For the first time we found that the eddies in the northern SCS extend from the surface to the sea bottom and display prominent tilted structures in the vertical. The AE was suggested to be shed from the Kuroshio current, which intruded into the SCS through Luzon Strait in winter. For the CE, its generation was associated with the barotropic instability of the Kuroshio current. By conducting an eddy energy budget analysis, we further identified that generation of submesoscale motions constitutes the dominant mechanism for the eddy dissipation. The findings in this study, not only provides new insights into the 3D structure of oceanic eddies, but also contributes to

  15. RSM Outlook Spring 2007 : Green Technology: The New IT

    NARCIS (Netherlands)

    R. Morris (Rebecca)

    2007-01-01

    markdownabstract#### Sustaining change (Rebecca Morris) An interview with RSM alumnus and Royal DSM Managing Board member Feike Sijbesma. #### Why celebrity sells: The brain mechanisms of persuasion (Vittorio Busato & Rebecca Morris) Marketing researchers at RSM are combining the latest

  16. 2822-IJBCS-Article-Rebecca Nguessan

    African Journals Online (AJOL)

    hp

    evaluated by the PHQ9. The biological material consisted of the umbilical cord blood of newborns and mothers' venous blood in which the blood count was performed. Anemia was present in 64.1% of depressed ..... le fait des conditions de prélèvement liées à la présence d'anticoagulant ou par la contamination du liquide ...

  17. Through the EU's Back and Front Doors

    DEFF Research Database (Denmark)

    Adler-Nissen, Rebecca

    2015-01-01

    Through the EU's front- and backdoors: The selective Danish and Norwegian approaches in the Area of Freedom, Security and Justice Rebecca Adler-Nissen......Through the EU's front- and backdoors: The selective Danish and Norwegian approaches in the Area of Freedom, Security and Justice Rebecca Adler-Nissen...

  18. The DISAM Journal of International Security Assistance Management. Volume 31, Number 1, March 2009

    Science.gov (United States)

    2009-03-01

    2005. Russia has been a strong competitor for the lead in arms transfer agreements with developing nations, ranking second every year from 2000...pre- holiday trip, and he said he stands by his earlier assessment that “we are not winning” the war there. “I said it because I believed it, and I...each SMEE. Delaware, Washington, D.C., Rhode Island, South Dakota, and the Virgin Islands are working with their Caribbean partners to collaborate on

  19. 2568-IJBCS-Article-Rebecca Enow T

    African Journals Online (AJOL)

    hp

    HIV/HBV/HCV multiple infection rates were 6(1.48%), 7(1.72%), 5(1.23%) and .... available on HCV morbidity and mortality in. Africa. Of those HCV-infected .... three infections as illustrated in Figure 1. ... positive only and HIV negative pregnant.

  20. 2332-IJBCS-Article-Rebecca Chukwu Anckwu

    African Journals Online (AJOL)

    hp

    1Medical Laboratory Science Department, Nnamdi Azikiwe University, Nnewi ... of these laboratories lack consistent sources of electricity and clean water. ... Quality assurance programs including quality control and external quality .... background material, providing a contrast ... appearance of one colored line at the control.

  1. RSM Outlook Spring 2007: Green Technology: The New IT

    OpenAIRE

    Morris, Rebecca

    2007-01-01

    markdownabstract#### Sustaining change (Rebecca Morris) An interview with RSM alumnus and Royal DSM Managing Board member Feike Sijbesma. #### Why celebrity sells: The brain mechanisms of persuasion (Vittorio Busato & Rebecca Morris) Marketing researchers at RSM are combining the latest neuroimaging techniques to discover more about what goes on in the brains of consumers. For marketeers, this may help take the last remaining guesswork out of pricey advertising campaigns. #### Green technolog...

  2. An investigation into the move towards electronic journals: a case study of NHS libraries in Kent, Surrey and Sussex.

    Science.gov (United States)

    England, Rebecca

    2013-09-01

    Electronic journals are so embedded into practice in academic libraries that it is easy to forget that this is not the case everywhere. In NHS libraries, for example, the staff face a particular set of issues. This article is based on Rebecca England's dissertation on this topic, completed as part of the MSc Econ course in Information and Library studies at Aberystwyth University. Rebecca is E-resources Librarian at the Maidstone and Tunbridge Wells NHS Trust. She investigated the momentum towards electronic journals in NHS libraries in the Kent, Surrey and Sussex region and the potential for a regional purchasing consortium. © 2013 The author. Health Information and Libraries Journal © 2013 Health Libraries Group.

  3. Feedback of mechanical effectiveness induces adaptations in motor modules during cycling

    Science.gov (United States)

    De Marchis, Cristiano; Schmid, Maurizio; Bibbo, Daniele; Castronovo, Anna Margherita; D'Alessio, Tommaso; Conforto, Silvia

    2013-01-01

    Recent studies have reported evidence that the motor system may rely on a modular organization, even if this behavior has yet to be confirmed during motor adaptation. The aim of the present study is to investigate the modular motor control mechanisms underlying the execution of pedaling by untrained subjects in different biomechanical conditions. We use the muscle synergies framework to characterize the muscle coordination of 11 subjects pedaling under two different conditions. The first one consists of a pedaling exercise with a strategy freely chosen by the subjects (Preferred Pedaling Technique, PPT), while the second condition constrains the gesture by means of a real time visual feedback of mechanical effectiveness (Effective Pedaling Technique, EPT). Pedal forces, recorded using a pair of instrumented pedals, were used to calculate the Index of Effectiveness (IE). EMG signals were recorded from eight muscles of the dominant leg and Non-negative Matrix Factorization (NMF) was applied for the extraction of muscle synergies. All the synergy vectors, extracted cycle by cycle for each subject, were pooled across subjects and conditions and underwent a 2-dimensional Sammon's non-linear mapping. Seven representative clusters were identified on the Sammon's projection, and the corresponding eight-dimensional synergy vectors were used to reconstruct the repertoire of muscle activation for all subjects and all pedaling conditions (VAF > 0.8 for each individual muscle pattern). Only 5 out of the 7 identified modules were used by the subjects during the PPT pedaling condition, while 2 additional modules were found specific for the pedaling condition EPT. The temporal recruitment of three identified modules was highly correlated with IE. The structure of the identified modules was found similar to that extracted in other studies of human walking, partly confirming the existence of shared and task specific muscle synergies, and providing further evidence on the modularity

  4. 77 FR 8269 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-02-14

    .... Place: Mayflower Park Hotel, 405 Olive Way, Seattle, WA 98101. Contact Person: Rebecca Henry, Ph.D... 20814. Contact Person: Melinda Jenkins, Ph.D., Scientific Review Officer, Center for Scientific Review...

  5. Anatomy of a Cancer Treatment Scam

    Medline Plus

    Full Text Available ... Joshua Phillips Rohit Chopra Rebecca Kelly Slaughter Bureaus & Offices Bureau of Competition Bureau of Consumer Protection Bureau of Economics Office of Congressional Relations Office of Equal Employment Opportunity ...

  6. 78 FR 77553 - Proposed Agency Information Collection Activities; Comment Request

    Science.gov (United States)

    2013-12-23

    ...-3520. Issued in Washington, DC, on December 3, 2013. Rebecca Pennington, Chief Financial Officer. [FR... role these sectors of transportation play in the overall national economy, FRA is requesting OMB to...

  7. 78 FR 45169 - GENECTIVE SA; Availability of Plant Pest Risk Assessment, Environmental Assessment, Preliminary...

    Science.gov (United States)

    2013-07-26

    ... Chappes, France, seeking a determination of nonregulated status of maize (Zea mays L.) designated as event... Road Unit 147, Riverdale, MD 20737-1236; (301) 851-3927, email: rebecca.l[email protected

  8. Allergy and allergic diseases

    National Research Council Canada - National Science Library

    Kay, A. B

    2008-01-01

    ... and Other Tolerogenic Mechanisms in Allergy and Asthma, 83 Catherine Hawrylowicz and Cezmi A. Akdis 5 IgE and IgE Receptors, 103 Brian J. Sutton, Andrew J. Beavil, Rebecca L. Beavil and James Hunt...

  9. Boots on the Ground: Maricopa County

    Centers for Disease Control (CDC) Podcasts

    In this podcast, we talk to CDC career epidemiology field officer Rebecca Sunenshine about her response efforts to a suspected tuberculosis case aboard a US Airways flight and the development of an airport emergency response plan.

  10. Knuckle Cracking

    Science.gov (United States)

    ... Don’t I Have to Lose Weight for Exercise to Have Health Benefits? Dr. Rebecca Manno answers if weight loss is necessary for exercise to have health benefits. I am fatigued, won’t exercise make it ...

  11. Communication networks: key to success of new technologies.

    Science.gov (United States)

    Woodward, M P.

    2001-06-01

    The Discussion Forum provides a medium for airing your views on any issues related to the pharmaceutical industry and obtaining feedback and discussion on these views from others in the field. You can discuss issues that get you hot under the collar, practical problems at the bench, recently published literature, or just something bizarre or humorous that you wish to share. Publication of letters in this section is subject to editorial discretion and company-promotional letters will be rejected immediately. Furthermore, the views provided are those of the authors and are not intended to represent the views of the companies they work for. Moreover, these views do not reflect those of Elsevier, Drug Discovery Today or its editorial team. Please submit all letters to Dr Rebecca Lawrence, News & Features Editor, Drug Discovery Today, e-mail: Rebecca.Lawrence@current-trends.com

  12. 276----14 Dec 2009 [Final version].indd

    African Journals Online (AJOL)

    2009-12-14

    Dec 14, 2009 ... study of authors themselves (the literate few) and in studies of analogy and ..... power. The expectation of future vindication, even taking part in divine judgment ...... Anna Rebecca Solevåg (PhD candidate, Oslo. University ...

  13. Kas meediatsirkus? / Katrin Kivimaa

    Index Scriptorium Estoniae

    Kivimaa, Katrin, 1969-

    2006-01-01

    Turner Prize'i 2006. a. kunstipreemia näitusest Londonis Tate-Britainis. Nominente oli neli: Tomma Abts, Mark Titchner, Phil Collins ja Rebecca Warren. Preemia pälvis saksa-inglise maalikunstnik Tomma Abts. Pikemalt Phil Collinsi videost "Reaalse naasmine"

  14. 78 FR 25941 - Stine Seed Farm, Inc.; Extension of a Determination of Nonregulated Status of Corn Genetically...

    Science.gov (United States)

    2013-05-03

    ... status, an analysis of other scientific data, and comments received from the public in response to a... our written determination, final environmental assessment, plant pest risk assessment, and our finding... INFORMATION CONTACT: Dr. Rebecca Stankiewicz Gabel, Chief, Biotechnology Environmental Analysis Branch...

  15. Neuromodulators for Aging Skin

    Science.gov (United States)

    ... Light treatment to the skin and Restylane to tear troughs and outer eyebrow. Photo courtesy of Rebecca Fitzagerald, MD - Los Angeles, California Possible risks Soreness Mild bruising Temporary weakness of surrounding muscles Headache Drooping eyelid Why choose neuromodulators for aging ...

  16. 78 FR 26062 - Proposed Information Collection: National Blueways System Application

    Science.gov (United States)

    2013-05-03

    ... proposed public information collection necessary as part of the process to nominate a river and associated... be nominated voluntarily for National Blueways recognition by stakeholder partnerships, in... Management and Budget control number. Dated: April 25, 2013. Rebecca Wodder, Senior Advisor to the Secretary...

  17. Improving Image Segmentation with Adaptive, Recurrent, Spiking Neural Network Models of the Primary Visual Cortex

    Science.gov (United States)

    2017-05-19

    Vijay Singh, Martin Tchernookov, Rebecca Butterfield, Ilya Nemenman, Rongrong Ji. Director Field Model of the Primary Visual Cortex for Contour...FTE Equivalent: Total Number: DISCIPLINE Vijay Singh 40 Physics 0.40 1 PERCENT_SUPPORTEDNAME FTE Equivalent: Total Number: Martin Tchernookov 0.20

  18. New Zealand cuts health spending to control costs

    OpenAIRE

    2010-01-01

    New Zealand’s health-care system is undergoing a series of cutbacks to reduce costs, but critics are concerned that the health of people on low incomes and in some population groups may suffer. Rebecca Lancashire reports in our series on health financing.

  19. Book Review: The Basics of Digital Forensics: The Primer for Getting Started in Digital Forensics

    Directory of Open Access Journals (Sweden)

    Stephen Larson

    2014-03-01

    Full Text Available Sammons, John. (2012. The Basics of Digital Forensics: The Primer for Getting Started in Digital Forensics. Waltham, MA: Syngress, 208 pages, Print Book ISBN: 9781597496612.eBook ISBN : 9781597496629. Print: US $29.95. eBook: US$20.97. Includes exercises, case studies, references, and index.Reviewed by Stephen Larson, PhD. Assistant Professor, Slippery Rock University of PAThe Basics of Digital Forensics: The Primer for Getting Started in Digital Forensics is well-named–it really is very basic. And it should be, as the book’s intended audience includes entry-level digital forensics professionals and complimentary fields such as law enforcement, legal, and general information security. Though the copyright is 2012, some of the data is from 2009, and there is mention of estimates for 2010.(see PDF for full review

  20. Sero-prevalence of Human Immunodeficiency Virus and hepatitis ...

    African Journals Online (AJOL)

    Sero-prevalence of Human Immunodeficiency Virus and hepatitis viruses and their correlation with CD4 T-cell lymphocyte counts in pregnant women in the Buea Health District of Cameroon. Rebecca Enow Tanjong, Pride Teyim, Henry Lucien Kamga, Edwin Suh Neba, Theresia Nkuo-Akenji ...

  1. 75 FR 58363 - Membership of the National Oceanic and Atmospheric Administration Performance Review Board

    Science.gov (United States)

    2010-09-24

    ...: Louisa Koch, Director, Office of Education Office of Education. Maureen E. Wylie, Chief Financial Officer Office of the Chief Financial Officer. Rebecca J. Lent, Director, International Affairs National Marine.... Culpepper, Chief Human Capital Officer National Institute of Standards and Technology, DOC. Charles S. Baker...

  2. 75 FR 52487 - Medicare Program; Payment Policies Under the Physician Fee Schedule and Other Revisions to Part B...

    Science.gov (United States)

    2010-08-26

    ... of services. FOR FURTHER INFORMATION CONTACT: Rebecca Cole, (410) 786-4497. SUPPLEMENTARY INFORMATION...). On page 40180, in our discussion of the four disease modules covered by the proposed PQRI group... disease modules. On page 40186, in our discussion of the proposed Physician Quality Reporting Initiative...

  3. RSM Outlook Summer 2013 : Making Business Social

    NARCIS (Netherlands)

    J. Whittern (Justine); D. Schreiner (Dorine)

    2013-01-01

    markdownabstract#### Improving the impact of social business (Rebecca Morris) Business is a powerful tool for solving social problems. However, more businesses need to focus on social issues if a greater impact is to be achieved. #### The business of social media (Joe Figueiredo) From blogs

  4. Research Article (PLOS ONE) Efficacy of a low-cost bubble CPAP ...

    African Journals Online (AJOL)

    2014-01-29

    Jan 29, 2014 ... Department of Respiratory Care, Texas Children's Hospital, Houston, Texas, U.S.A.. Correspondence to: Rebecca R. Richards-Kortum (rkortum@rice.edu). Abstract. Background. Respiratory failure is a leading cause of neonatal mortality in the developing world. Bubble continuous positive airway pressure ...

  5. In the Flow of Media, Religion, and Culture: A Case Study with TVbyGIRLS

    Science.gov (United States)

    Bischoff, Claire; Bullen, Rebecca Richards; Nemer, Molly; Quednau, Rachel

    2011-01-01

    This article introduces TVbyGIRLS, a nonprofit organization supporting girls in the development of critical thinking, digital literacy and storytelling, leadership, compassionate collaboration, and social justice engagement. Religious educator Claire Bischoff interviews Rebecca Richards Bullen, TVbyGIRLS mentor, and Molly Nemer and Rachel Quednau,…

  6. Eyes on the Road

    Centers for Disease Control (CDC) Podcasts

    One of the first lessons new drivers learn is to keep their eyes on the road. Unfortunately, cell phones and other electronic devices are causing many drivers to lose their focus, and sometimes their lives. In this podcast, Rebecca Naumann discusses the dangers of distracted driving.

  7. RSM Outlook Summer 2008 : Entrepreneurship: The Leap of Faith

    NARCIS (Netherlands)

    R. Morris (Rebecca); L. Sawahata (Lesa)

    2008-01-01

    markdownabstract#### What it takes to be an entrepreneur (Stephen Hoare, Rebecca Morris) Starting your own business is the stuff of capitalist dreams, with multitudes leaving behind the comfort of their salaried positions each year to attempt it. These RSM alumni are lucky enough to be able to

  8. 76 FR 42771 - Medicare Program; Payment Policies Under the Physician Fee Schedule and Other Revisions to Part B...

    Science.gov (United States)

    2011-07-19

    ... Payment Window. Pam West, (410) 786-2302, for issues related to the technical corrections. Rebecca Cole or... artery bypass graft CAD--Coronary artery disease CAH--Critical Access Hospital CAHEA--Committee on Allied... Program CBSA--Core-Based Statistical Area CDC--Centers for Disease Control and Prevention CEM--Cardiac...

  9. The Practices of Geography

    Science.gov (United States)

    Bednarz, Sarah Witham

    2016-01-01

    Sarah Bednarz begins by thanking Rebecca Theobald for the invitation to contrubute to this issue of "The Geography Teacher"("TGT"). As a member of the National Council for Geographic Education (NCGE) Publications Committee and coeditor of the "Journal of Geography," Bednarz confesses that she was not favorably…

  10. Changing the Rules of the Game: Indigenous Economics.

    Science.gov (United States)

    Adamson, Rebecca

    1995-01-01

    Rebecca Adamson, president and founder of First Nations Development Institute, compares the values of traditional American Indian economies that stress sustainability and limited inequalities among society members with the deficiencies of the Western economic system. Discusses First Nations Development Institute's view of Indian gaming and how it…

  11. 77 FR 72721 - Fees on Health Insurance Policies and Self-Insured Plans for the Patient-Centered Outcomes...

    Science.gov (United States)

    2012-12-06

    ... 1545-BK59 Fees on Health Insurance Policies and Self-Insured Plans for the Patient-Centered Outcomes... Patient Protection and Affordable Care Act on issuers of certain health insurance policies and plan... arrangements) or Rebecca L. Baxter at (202) 622-3970 (regarding health insurance policies). SUPPLEMENTARY...

  12. 77 FR 19338 - Notice of Amendment to Proposed Exemption Sammons Enterprises, Inc. Employee Stock Ownership Plan...

    Science.gov (United States)

    2012-03-30

    ..., as amended (ERISA), and the Internal Revenue Code of 1986, as amended (the Code). The proposed... likely the product of the following representation made in the original application submitted to the... provides to the I/F, in a timely fashion, all information reasonably requested by the I/F to assist it in...

  13. Investigation of Hydrophobic Concrete Additive for Seawall Replacement at Pililaau Army Recreation Center, Hawaii

    Science.gov (United States)

    2017-05-01

    Eugene Arter – Engineering Technician, US Army Garrison Hawaii (USAP-PTA/DPW) The Commander of ERDC was COL Bryan S. Green , and the Director was...fully demonstrate and validate the technology. ERDC-CERL TR-17-10 22 References Herzberg, Eric F., Norman T. O’Meara, and Rebecca F. Stroh

  14. Psychology: Teacher Supplement.

    Science.gov (United States)

    Stark, Rebecca

    This supplement provides teachers with tests, quizzes, answers to questions in the text, and general teaching information for using the student text, "Psychology," by Rebecca Stark. Quizzes included are on the topics of human development; the nervous system; the brain; cognitive development; sensation and perception; conditioning; learning;…

  15. 75 FR 40039 - Medicare Program; Payment Policies Under the Physician Fee Schedule and Other Revisions to Part B...

    Science.gov (United States)

    2010-07-13

    ... INFORMATION CONTACT: Rebecca Cole, (410) 786-4497, for issues related to physician payment and for all other... issues related to renal dialysis provisions and payments for end-stage renal disease facilities. Diane...-State Renal Disease Related Services for Home Dialysis (CPT Codes 90963, 90964, 90965, and 90966) 1. End...

  16. 76 FR 58277 - Performance Review Board Members

    Science.gov (United States)

    2011-09-20

    .... Cantrell, Patrick H. Conway, Kathleen M. Crosby, John Czajkowski, Cheryl R. Dammons, Michelle S. Davis..., William B. Schultz, Neil Shapiro, Jeremy B. Sharp, George H. Sheldon, Steven D. Silverman, Rebecca T... E. Tyler Jr., Stephen J. Veneruso, Karen V. Walker Bryce, Luis A. Wilmot, Holly J. Wong, Robert K...

  17. School Libraries and Student Learning: A Guide for School Leaders

    Science.gov (United States)

    Morris, Rebecca J.

    2015-01-01

    Innovative, well-designed school library programs can be critical resources for helping students meet high standards of college and career readiness. In "School Libraries and Student Learning", Rebecca J. Morris shows how school leaders can make the most of their school libraries to support ambitious student learning. She offers…

  18. The online Self

    NARCIS (Netherlands)

    Gloerich, I.; van Dipten, L.; Rasch, M.D.

    2017-01-01

    Following the conference Fear and Loathing of the Online Self and the publication of Culture of the Selfie: Self-Representation in Contemporary Visual Culture in May 2017, this episode of INC’s Zero Infinite podcast zooms in on the online self and selfies, with Ana Peraica, Wendy Chun and Rebecca

  19. Review Symposium. "Working in America: A Blueprint for the New Labor Market," by Paul Osterman, Thomas A. Kochan, Richard Locke, and Michael J. Piore.

    Science.gov (United States)

    Katz, Harry C., Ed.

    2002-01-01

    A panel comments on the book, Working in America, and implications for the U.S. labor market, including declining traditional internal labor markets, the need for private versus public policy interventions, international labor policy, and value-based policy. Commentators include David Neumark, Peter Cappelli, Sanford M. Jacoby, Rebecca M. Blank,…

  20. Parental Kidnaping and Child Support. Hearing before the Subcommittee on Juvenile Justice of the Committee on the Judiciary. United States Senate, Ninety-Ninth Congress, First Session on Problems of Domestic and International Kidnaping and Child Support Enforcement (July 19, 1985).

    Science.gov (United States)

    Congress of the U.S., Washington, DC. Senate Committee on the Judiciary.

    This document presents witness testimonies and prepared statements from the Senate hearing on parental kidnapping and child support. Opening statements are included from Senators Arlen Specter and Mich McConnell. Rebecca Hickman testifies about her experience when her daughter was abducted by the noncustodial father and taken to Iran. Hickman asks…

  1. Professor Adler-Nissen om TED-Talks i Kristeligt Dagblad

    DEFF Research Database (Denmark)

    Adler-Nissen, Rebecca

    2017-01-01

    Professor Rebecca Adler-Nissen var den 10. juni 2017 i Kristeligt Dagblad i forbindelse med hendes TED Talk på TED konferencen i Danmark. Her talte Adler-Nissen om international diplomati. Adler-Nissen ser TED formatet som en måde at øge kendskabet til emnet international diplomati, da formatet...

  2. Keeping Older Drivers Safe on the Road

    Centers for Disease Control (CDC) Podcasts

    2010-03-15

    In this podcast, Rebecca Naumann, MPH, an epidemiologist from CDC's Injury Center, talks about steps older adults can take to stay safer on the road.  Created: 3/15/2010 by National Center for Injury Prevention and Control, Division of Unintentional Injury Prevention.   Date Released: 3/15/2010.

  3. Beyond Relation: A Critical Exploration of "Relational Consciousness" for Spiritual Education

    Science.gov (United States)

    Wills, Ruth

    2012-01-01

    This paper takes a philosophical view of the spiritual concept "relational consciousness" first proposed by Rebecca Nye in 1998. I will consider the "relational" aspect of spirituality through the ontology of Heidegger and the dialogical relationship "I and Thou" of Martin Buber, examining the problems that contingency and mediation within…

  4. Internationally recognized human rights' before the International Criminal Court / Rebecca Young

    Index Scriptorium Estoniae

    Young, Rebecca

    2011-01-01

    Õiguse kohaldamisest ja tõlgendamisest kooskõlas rahvusvaheliselt tunnustatud inimõigustega tulenevalt ICC Rooma Statuudi artiklist 21 ja Rahvusvaheliste lepingute õiguse Viini konventsiooni artiklitest 31 ja 32

  5. Building Communities of Care for Military Children and Families

    Science.gov (United States)

    Kudler, Harold; Porter, Rebecca I.

    2013-01-01

    Military children don't exist in a vacuum; rather, they are embedded in and deeply influenced by their families, neighborhoods, schools, the military itself, and many other interacting systems. To minimize the risks that military children face and maximize their resilience, write Harold Kudler and Colonel Rebecca Porter, we must go beyond…

  6. Gender | Page 178 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Gender. Sexospécificités. Co-founder Rebecca Chiao on her speaking tour of Canada ... As the world observes World Health Day on April 7, IDRC asked researchers: ... Researchers supported by IDRC focus on the root causes of inequities and ... with high and/or growing inequalities, and inequality can hamper growth.

  7. ANALYSIS OR THE POTENTIAL SPERM BIOMARKER, SP22, IN HUMAN SEMEN

    Science.gov (United States)

    ANALYSIS OF THE POTENTIAL SPERM BIOMARKER SP22 IN HUMAN SEMEN Rebecca A. Morris Ph.D.1, Gary R. Klinefelter Ph.D.1, Naomi L. Roberts 1, Juan D. Suarez 1, Lillian F. Strader 1, Susan C. Jeffay 1 and Sally D. Perreault Ph.D.1 1 U.S. EPA / ORD / National Health a...

  8. When Claiming to Teach for Social Justice Is Not Enough: Majoritarian Stories of Race, Difference, and Meritocracy

    Science.gov (United States)

    Viesca, Kara Mitchell; Torres, Aubrey Scheopner; Barnatt, Joan; Piazza, Peter

    2013-01-01

    To understand how dominant messages about race and effective pedagogy impact teacher beliefs and practice, this study employs critical race theory (CRT) in a case study analysis of Rebecca Rosenberg, a mid-career entrant into the teaching profession who was terminated from her first job before the end of her district's probationary period. Despite…

  9. Decreasing Nonmarital Births and Strengthening Marriage to Reduce Poverty

    Science.gov (United States)

    Amato, Paul R.; Maynard, Rebecca A.

    2007-01-01

    Since the 1970s, the share of U.S. children growing up in single-parent families has doubled, a trend that has disproportionately affected disadvantaged families. Paul Amato and Rebecca Maynard argue that reversing that trend would reduce poverty in the short term and, perhaps more important, improve children's growth and development over the long…

  10. What Works in Girls' Education: Evidence for the World's Best Investment

    Science.gov (United States)

    Sperling, Gene B.; Winthrop, Rebecca

    2015-01-01

    Gene Sperling, author of the seminal 2004 report published by the Council on Foreign Relations, and Rebecca Winthrop, director of the Center for Universal Education, have written this definitive book on the importance of girls' education. As Malala Yousafzai expresses in her foreword, the idea that any child could be denied an education due to…

  11. Real Economies in Africa | Hardin | CODESRIA Bulletin

    African Journals Online (AJOL)

    Real Economies in Africa. Rebecca Hardin, Una Okonkwo. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact AJOL · News. OTHER RESOURCES... for Researchers · for Journals · for Authors ...

  12. VizieR Online Data Catalog: Low-mass stars in 25 Ori group and Orion OB1a (Suarez+, 2017)

    Science.gov (United States)

    Suarez, G.; Downes, J. J.; Roman-Zuniga, C.; Covey, K. R.; Tapia, M.; Hernandez, J.; Petr-Gotzens, M. G.; Stassun, K. G.; Briceno, C.

    2017-09-01

    The V, R, and I photometry used in this work was obtained from the Centro de Investigaciones de Astronomia (CIDA) Deep Survey of Orion (CDSO) catalog (Downes et al. 2014, Cat. J/MNRAS/444/1793), which was constructed by coadding the multi-epoch optical observations from the CIDA Variability Survey of Orion (CVSO; Briceno et al. 2005, Cat. J/AJ/129/907). The sensitivity limits of the CDSO covers the Low-Mass Star (LMS) and Brown Dwarf (BD) population of 25 Ori and its surroundings within the region 79.7°Eisenstein et al. 2011AJ....142...72E). The BOSS spectrograph has plates with 1000 fibers of 2'' diameter spanning a field of view of 3.0° in diameter and covering a wavelength range from 3560Å to 10400Å with a resolution of R=1560 at 3700Å and R=2650 at 9000Å (Gunn et al. 2006AJ....131.2332G; Smee et al. 2013AJ....146...32S). (4 data files).

  13. Military and Veterans Disability System. Pilot Has Achieved Some Goals, but Further Planning and Monitoring Needed

    Science.gov (United States)

    2010-12-01

    Member Subcommittee on Defense Committee on Appropriations House of Representatives The Honorable Chet Edwards Chairman The Honorable Zach Wamp...and Vanessa Taylor provided assistance with research methodology and data analysis. Bonnie Anderson, Rebecca Beale, Mark Bird, Brenda Farrell...Valerie Melvin, Patricia Owens, and Randall Williamson provided subject matter expertise. Susan Bernstein and Kathleen van Gelder provided writing

  14. Learning about Plants with STEAM: In a Yearlong Unit on Plants, Students Use Art to Make Models of Their Subjects

    Science.gov (United States)

    Kurson, Rebecca

    2016-01-01

    In this article Rebecca Kurson describes her school garden, now in its second year, as one that the lower school (preK-5) students plant and observe as often as possible. They call the garden an "outdoor classroom," and the younger students are particularly interested in how the plants grow. Kruson had lots of garden activities…

  15. Boots on the Ground: Maricopa County

    Centers for Disease Control (CDC) Podcasts

    2014-04-09

    In this podcast, we talk to CDC career epidemiology field officer Rebecca Sunenshine about her response efforts to a suspected tuberculosis case aboard a US Airways flight and the development of an airport emergency response plan.  Created: 4/9/2014 by Office of Public Health Preparedness and Response (PHPR).   Date Released: 4/9/2014.

  16. Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment | Poster

    Science.gov (United States)

    Noriho Iida, Amiran Dzutsev, C. Andrew Stewart, Loretta Smith, Nicolas Bouladoux, Rebecca A. Weingarten, Daniel A. Molina, Rosalba Salcedo, Timothy Back, Sarah Cramer, Ren-Ming Dai, Hiu Kiu, Marco Cardone, Shruti Naik, Anil K. Patri, Ena Wang, Francesco M. Marincola, Karen M. Frank, Yasmine Belkaid, Giorgio Trinchieri, Romina S. Goldszmid Science 342(6161):967-970, 2013

  17. Author Details

    African Journals Online (AJOL)

    White, Rebecca L. Vol 2, No 2 (2015): Series F - Articles Abstract: Trauma Tapping Technique: Practical First Aid for Stress and Trauma Abstract PDF. ISSN: 2305-2678. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

  18. Interviewing for an Interdisciplinary Job: Principled Goals, Pragmatic Outcomes, and Finding the Right Fit in Academia

    Science.gov (United States)

    Clark, Susan G.; Steelman, Toddi A.

    2013-01-01

    This paper sets up a scenario about Rebecca, a jobseeker, who is a fictitious composite, a "typical" candidate who wants a position at a college/university. A job description is provided. She interviews for the advertised position, and while doing so, she also interviews the university, school/department, and working environment to see if there is…

  19. Author Details

    African Journals Online (AJOL)

    Assa, Rebecca Rachel. Vol 10, No 3 (2016) - Articles Variation des paramètres biochimiques de l'eau de coco (Cocos nucifera L.) issu de la culture in vitro pendant la période de stockage. Abstract PDF. ISSN: 1997-342X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors ...

  20. Think Aloud in Groups: Mediating Poetry for Children with Cecília Meireles, Paulo Freire, and John Dewey

    Science.gov (United States)

    Diniz, Telma Franco

    2018-01-01

    As suggested by its title, this article reports on a Think Aloud in Group (TAG) practice in which a group of Y5 children thought aloud the poem "The Blue Boy", written in Portuguese by Cecília Meireles and translated into English by Sarah Rebecca Kersley. As a dialogical and collaborative literacy practice, TAG aims to transform the…

  1. Spring Research Festival Highlighted on WHAG-TV | Poster

    Science.gov (United States)

    WHAG-TV (Hagerstown, Md.) visited Fort Detrick to highlight the 2015 Spring Research Festival (SRF), sponsored by the National Interagency Confederation for Biological Research (NICBR). Visit the WHAG-TV website to see the video broadcast, which aired May 6. The video was produced by WHAG Reporter Mallory Sofastaii. The video featured Linganore High School senior Rebecca

  2. Interview with Smithsonian NASM Spacesuit Curator Dr. Cathleen Lewis

    Science.gov (United States)

    Lewis, Cathleen; Wright, Rebecca

    2012-01-01

    Dr. Cathleen Lewis was interviewed by Rebecca Wright during the presentation of an "Interview with Smithsonian NASM Spacesuit Curator Dr. Cathleen Lewis" on May 14, 2012. Topics included the care, size, and history of the spacesuit collection at the Smithsonian and the recent move to the state-of-the-art permanent storage facility at the Udvar-Hazy facility in Virginia.

  3. Sexospécificités | Page 20 | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    La cofondatrice de HarassMap, Rebecca Chiao, revient sur sa tournée de conférences au Canada. Encore une fois, le harcèlement sexuel fait les manchettes en Égypte, en raison des agressions et des viols collectifs qui surviennent pendant les manifestations; mais il s'agit aussi d'un véritable fléau avec lequel presque ...

  4. Eyes on the Road (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    2013-03-14

    One of the first lessons new drivers learn is to keep their eyes on the road. Unfortunately, cell phones and other electronic devices are causing many drivers to lose their focus, and sometimes their lives. In this podcast, Rebecca Naumann discusses the dangers of distracted driving.  Created: 3/14/2013 by MMWR.   Date Released: 3/14/2013.

  5. Global Security Contingency Fund: Summary and Issue Overview

    Science.gov (United States)

    2014-04-04

    Diplomacy and Development Review (QDDR), Washington, D.C., December 2010, p. 203; Gordon Adams and Rebecca Williams, A New Way Forward: Rebalancing ...Williams, A New Way Forward: Rebalancing Security Assistance Programs and (continued...) Global Security Contingency Fund: Summary and Issue Overview...a large security assistance portfolio . But others may point to the State Department’s creation of new programs under the Security Assistance

  6. Cosplay e cosplayers: quando a cultura pop é levada a sério

    Directory of Open Access Journals (Sweden)

    Barbara Heller

    2016-08-01

    Full Text Available Cena Cosplay: comunicação, consumo, memória nas culturas juvenis, organizado por Monica Rebecca Ferrari Nunes, apresenta os resultados de pesquisa com financiamento do CNPq levado a termo por investigadores que a autora coordena no grupo vinculado ao Programa de Pós-Graduação em Comunicação e Práticas de Consumo da ESPM, - SP. Dividido em sete partes, além da apresentação, o livro trabalha em mão dupla: as memórias das narrativas que despertaram o interesse para a prática cosplay e seu "inverso", isto é, as estratégias pelas quais a cena cosplay garante sua memória nas culturas juvenis. Iuri Lotman, Paul Zumthor, Marshall McLuhan, Monica Rebecca Ferrari Nunes, Roger Silverstone, Mircea Eliade, entre outros, dão sustentação teórica às conclusões dos dez autores dos capítulos que frequentaram, entre 2012 e início de 2014, os eventos dos animês em São Paulo, Belo Horizonte, Rio de Janeiro e Vitória.

  7. Cyberspace: A Lawless World

    Science.gov (United States)

    2016-02-01

    fraud and forgery, (3) child pornography, and (4) copyright infringements.18 The convention also requires signatories to establish domestic...William Perdue, and Julia Spiegal, “The Law of Cyber-Attack,” Faculty Scholarship Series, Paper 3852, January 2012. 50 NATO Cooperative Cyber...SANS Institute, 2015. 31 Hathaway, Oona A., Rebecca Crootof, Philip Levitz, Haley Nix, Aileen Nowlan, William Perdue, and Julia Spiegal. “The Law of

  8. Flexure Strength and Optical Transparency of Magnesium-Aluminate Spinel (MgAlO4): Influence of Polishing and Glass Coating

    Science.gov (United States)

    2016-12-01

    Eugene Shanholtz, Jian Yu, Rebecca L Walker, and John J Pittari III. Approved for public release; distribution is unlimited. vi INTENTIONALLY...with high transparency necessitate the use of aggressive densification techniques that result in very coarse microstructures (i.e., average grain sizes...windows. Glass coating (or glazing) is a common technique used to strengthen ceramics. The use of glazing as a strengthening technique , however, is

  9. Bug Distribution and Pattern Classification.

    Science.gov (United States)

    1985-07-15

    Center Educational Psychology University of Leyden San Diego. CA 92152 Urbana. IL 61801 Education Research Center oernaavelaan 2 Dr. Erling B. Andersen...Dr. Dattprasad rlivgi 23314 EN Leyden Department of Statistics Syracuse University The NETHERLANDS 3tudiestraede 6 Department of Psychology 1455...Rebecca Hetter Learning R&D Center Navy Personnel R&D Center University of Pittsburgh Ms. Kathleen Moreno Code 62 Pittsburgh, PA 15260 Navy Personnel R

  10. MFA Graduate Show 2015: In the Usual Direction of Travel

    OpenAIRE

    2015-01-01

    Avgangsstudenter: Patrik Berg, Christian Magnus Tømmeraas Berg, Maia Birkeland, Matilda Björkne, Stine Bråthen, Stein Are Kjærås Dahl, Emil Gustafsson, Jeanett Gustavsen, hÅkon gÅre, Jørgen Frederik Scheel Haarstad, Anita Hanch-Hansen, Elin Hedberg, Andrea Wikhammer Heir, Steinar Laumann, Aron-Irving Li, Tina Lindvall, Rebecca Szabo Onstad, Zahra Rashid, Hege Cathrine Hauge Thoresen

  11. Un partenariat entre l'Ouganda et le Canada fait avancer les études ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    21 juin 2016 ... Karen D. Schwartz, Youn-Young Park, and Ssanyu Rebecca. Selon les statistiques, 20 % des Ougandais présentent un handicap physique. Malgré tout, peu de recherches ont été menées dans le but de jeter un éclairage sur le vécu des personnes handicapées. Cette absence d'études officielles et de ...

  12. A study and simulation of the impact of high-order aberrations to overlay error distribution

    Science.gov (United States)

    Sun, G.; Wang, F.; Zhou, C.

    2011-03-01

    With reduction of design rules, a number of corresponding new technologies, such as i-HOPC, HOWA and DBO have been proposed and applied to eliminate overlay error. When these technologies are in use, any high-order error distribution needs to be clearly distinguished in order to remove the underlying causes. Lens aberrations are normally thought to mainly impact the Matching Machine Overlay (MMO). However, when using Image-Based overlay (IBO) measurement tools, aberrations become the dominant influence on single machine overlay (SMO) and even on stage repeatability performance. In this paper, several measurements of the error distributions of the lens of SMEE SSB600/10 prototype exposure tool are presented. Models that characterize the primary influence from lens magnification, high order distortion, coma aberration and telecentricity are shown. The contribution to stage repeatability (as measured with IBO tools) from the above errors was predicted with simulator and compared to experiments. Finally, the drift of every lens distortion that impact to SMO over several days was monitored and matched with the result of measurements.

  13. A Novel Mechanism for the Pathogenesis of Nonmelanoma Skin Cancer Resulting from Early Exposure to Ultraviolet Light

    Science.gov (United States)

    2015-11-01

    Ultraviolet Light PRINCIPAL INVESTIGATOR: Rebecca Morris, PhD CONTRACTING ORGANIZATION: University of Minnesota, Twin Cities Minneapolis, MN 55455-2070...stem cells in response to damage, and 2) bone marrow may be a long-lived reservoir of sunlight initiated stem cells that can repopulate the skin even...proposed that sunburn following exposure to sunlight has the capacity to make skin stem cells migrate. In this Discovery award we challenged the

  14. Instructional Leadership as Defined by Virginia Elementary Title I Principals: a Delphi Study

    OpenAIRE

    Eastwood, Rebecca G.

    2012-01-01

    Rebecca G. Eastwood Abstract Policymakers have tried to link the principal to student outcomes, thus shifting the role of the principal from manager to instructional leader of the school. The significance of instructional leadership has increased especially since the implementation of the No Child Left Behind Act in January of 2002. However, a common definition of instructional leadership is difficult to locate in the literature. In this three-round Delp...

  15. Final Base Realignment and Closure (BRAC) Environmental Assessment for Realignment of Nellis Air Force Base

    Science.gov (United States)

    2007-03-01

    weapons systems in support of potential technological improvements in hardware, software , tactics, and training. In recent years, the total amount of...communities in southeastern California, southern Nevada, western and southern Arizona, southwestern Utah, and through Sonora and northern Sinaloa, Mexico ...Publ ic Utilities Commi ssion Pete Konesky , Stat e Energy Of f i ce Rebecca Pa l me r , State Historic Preservation Office Alisa Huckle, ONR Libr a

  16. Hamas and Israel: Conflicting Strategies of Group-Based Politics

    Science.gov (United States)

    2008-12-01

    Justice, Durham and London: Duke University Press, 1990, pp. 189-197. 3. Many works deal with this issue. A detailed study of the city of Acre is...instructive. Rebecca L. Torstrick, The Limits of Coexistence: Identity Politics in Israel, Ann Arbor : University of Michigan Press, 2000. 4. Alisa...as with “Intifadha farms,” raising produce, chickens , and dairy cows, and boycotting Israeli products, refusing to pay taxes, and in merchants

  17. Quantifying the Bering Strait Oceanic Fluxes and their Impacts on Sea-Ice and Water Properties in the Chukchi and Beaufort Seas and Western Arctic Ocean for 2013-2014

    Science.gov (United States)

    2016-07-27

    impacts on sea-ice and water properties in the Chukchi and Beaufort Seas and western Arctic Ocean for 2013-2014 Rebecca Woodgate Polar Science...and G. R. Bigg (2002), Impact of flow through the Canadian Archipelago and Bering Strait on the North Atlantic and Arctic circulation: an ocean ...Technical 3. DATES COVERED (From - To) Feb 2013 - April 2016 4. TITLE AND SUBTITLE Quantifying the Bering Strait oceanic fluxes and their impacts

  18. On Cybersecurity, Crowdsourcing, and Social Cyber-Attack

    Science.gov (United States)

    2013-01-01

    gahran_1_android- app - android -phone-apple-s- app - store?_s=PM:TECH. Accessed January 9, 2013. DR. REBECCA GOOLSBY is a Program Officer with the Office of Naval...legitimate messages, and understand how quickly mobile apps and text services can disseminate false information. Authorities and volunteers must develop...inflammatory information and disinfor- mation. Like the conflicts sparked by Guttenberg’s invention, significant real-world impacts of a more troubled

  19. Lifestyle modification in the management of the metabolic syndrome: achievements and challenges

    OpenAIRE

    Riccardo Dalle Grave; Simona Calugi; Elena Centis; et al

    2010-01-01

    Riccardo Dalle Grave1, Simona Calugi1, Elena Centis2, Rebecca Marzocchi2, Marwan El Ghoch1, Giulio Marchesini21Department of Eating & Weight Disorder, Villa Garda Hospital, Garda (VR), Italy; 2Unit of Metabolic Diseases & Clinical Dietetics, Alma Mater Studiorum – University of Bologna, Bologna, ItalyAbstract: Lifestyle modification based on behavior therapy is the most important and effective strategy to manage the metabolic syndrome. Modern lifestyle modification t...

  20. National ornament and the imperial masquerade

    Directory of Open Access Journals (Sweden)

    Nóra Veszprémi

    2015-12-01

    Full Text Available Review of Rebecca Houze, Textiles, Fashion, and Design Reform in Austria–Hungary before the First World War: Principles of Dress: Rebecca Houze’s book is a thoroughly researched and original study of the impact of design reform on textile production and fashion in Austria-Hungary in the late nineteenth and early twentieth century which centres its argument around the Bekleidungsprinzip (“principle of dress” put forward by Gottfried Semper. It discusses the role of newly founded applied arts museums, industrial exhibitions, the concept of “house industry,” and the upsurge of interest in folk crafts in this process, while also placing a strong emphasis on the role of women as producers of textiles. One of the main virtues of the book is its wide scope which manages to investigate endeavours informed by different and sometimes opposed national and imperial interests in their complicated interconnectedness. It is a pity that this broad perspective is narrowed down in the second part of the book which focuses on with turn-of-the-century Vienna and does not deal with modernist tendencies in Hungarian design. Nevertheless, this part of the book also provides a fascinating discussion of its own subject, and the monograph as a whole is a valuable contribution to its field of study.

  1. DoD Civilian Training: Source, Content, Frequency and Cost

    Science.gov (United States)

    1994-03-01

    statistics. This especially includes Mr. Mike Dove, Ms. Kris Hoffman, Ms. Ninfa Camargo , Mr. Edward Christie, Ms. Rebecca Tag, Ms. Elizabeth Kundift Ms...Center, San Francisco , CA, will close. DoD Civilian Training Study Page 10 Chapter 2: Source There were 1,507 civilians trained We learned that 166...San Diego, CA Service School Command 13 60 San Diego, CA Submarine Training Facility 4 61 San Francisco , CA Naval Technical Training Center 13 62

  2. Steerability Analysis of Tracked Vehicles: Theory and User’s Guide for Computer Program TVSTEER

    Science.gov (United States)

    1986-08-01

    Baladi , Donald E. Barnes, Rebecca P. BergerC oStructures Laboratory NDEPARTMENT OF THE ARMY ___ Waterways Experiment Station, Corps of Engineers . U P0 Box...Analysis of Tracked Vehicles: Theory and User’s Guide for Computer Program TVSTEER - 12 PERSONAL AUTHOR(S) Baladi , George Y., Barnes, Donald E...mathematical model was formulated by Drs. George Y. Baladi and Behzad Rohani. The logic and computer programming were accomplished by Dr. Baladi and

  3. Pilot study on the additive effects of berberine and oral type 2 diabetes agents for patients with suboptimal glycemic control

    OpenAIRE

    Di Pierro, Francesco; Villanova,Nicola; Agostini,Federica; Soverini,Valentina; Marchesini,Giulio; Marzocchi,Rebecca

    2012-01-01

    Francesco Di Pierro,1 Nicola Villanova,2 Federica Agostini,2 Rebecca Marzocchi,2 Valentina Soverini,2 Giulio Marchesini21Scientific Department, Velleja Research, Milano, 2Diseases of Metabolism, S Orsola Malpighi Hospital, Bologna, ItalyBackground: Suboptimal glycemic control is a common situation in diabetes, regardless of the wide range of drugs available to reach glycemic targets. Basic research in diabetes is endeavoring to identify new actives working as insulin savers, use of which coul...

  4. Information Tailoring Enhancements for Large-Scale Social Data

    Science.gov (United States)

    2016-09-26

    person shall be subject to any penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number...Unclassified Unclassified Unclassified SAR 12 19a. NAME OF RESPONSIBLE PERSON Dr. Rebecca Goolsby 19b. TELEPHONE NUMBER flnclude area code) (703...Accounts: In addition to linking Twitter accounts, users can now link their Instagram accounts. This is encouraged because users can use their token (as

  5. New advancements and developments in treatment of renal cell carcinoma: focus on pazopanib

    Directory of Open Access Journals (Sweden)

    C Lance Cowey

    2010-09-01

    Full Text Available C Lance Cowey1, Guru Sonpavde2, Thomas E Hutson11Baylor-Sammons Cancer Center/Texas Oncology, PA, GU Oncology Program, Dallas, 2Baylor College of Medicine/Texas Oncology, PA, Houston, Texas, USAAbstract: With the recent approval of pazopanib, an oral multitargeted tyrosine kinase inhibitor which potently targets vascular endothelial growth factor receptors 1–3, platelet-derived growth factor, and c-kit, six agents are now available for use in the management of metastatic renal cell carcinoma (RCC. Pazopanib has shown improved progression-free survival compared with placebo in treatment-naïve or cytokine-treated patients with metastatic RCC in large Phase II and Phase III clinical trials. Pazopanib has demonstrated a tolerable side effect profile and is currently being compared with sunitinib in a Phase III noninferiority trial. In this review, the outcomes of the clinical testing of pazopanib are discussed, as well as a perspective on the placement of pazopanib among other approved agents.Keywords: renal cell carcinoma, targeted agents, vascular endothelial growth factor ­inhibitors, pazopanib

  6. Anglo-American views of Gavrilo Princip

    Directory of Open Access Journals (Sweden)

    Markovich Slobodan G.

    2015-01-01

    Full Text Available The paper deals with Western (Anglo-American views on the Sarajevo assassination/attentat and Gavrilo Princip. Articles on the assassination and Princip in two leading quality dailies (The Times and The New York Times have particularly been analysed as well as the views of leading historians and journalists who covered the subject including: R. G. D. Laffan, R. W. Seton-Watson, Winston Churchill, Sidney Fay, Bernadotte Schmitt, Rebecca West, A. J. P. Taylor, Vladimir Dedijer, Christopher Clark and Tim Butcher. In the West, the original general condemnation of the assassination and its main culprits was challenged when Rebecca West published her famous travelogue on Yugoslavia in 1941. Another Brit, the remarkable historian A. J. P. Taylor, had a much more positive view on the Sarajevo conspirators and blamed Germany and Austria-Hungary for the outbreak of the Great War. A turning point in Anglo-American perceptions was the publication of Vladimir Dedijer’s monumental book The Road to Sarajevo (1966, which humanised the main conspirators, a process initiated by R. West. Dedijer’s book was translated from English into all major Western languages and had an immediate impact on the understanding of the Sarajevo assassination. The rise of national antagonisms in Bosnia gradually alienated Princip from Bosnian Muslims and Croats, a process that began in the 1980s and was completed during the wars of the Yugoslav succession. Although all available sources clearly show that Princip, an ethnic Serb, gradually developed a broader Serbo-Croat and Yugoslav identity, he was ethnified and seen exclusively as a Serb by Bosnian Croats and Bosniaks and Western journalists in the 1990s. In the past century imagining Princip in Serbia and the West involved a whole spectrum of views. In interwar Anglo-American perceptions he was a fanatic and lunatic. He became humanised by Rebecca West (1941, A. J. P. Taylor showed understanding for his act (1956, he was fully

  7. Development of Less Toxic Treatment Strategies for Metastatic and Drug-Resistant Breast Cancer Using Noninvasive Optical Monitoring

    Science.gov (United States)

    2017-09-01

    Extractions An example of calibrated ( black ) and fit (red) amplitude and phase measured from 50 to 400 MHz in steps of 1 MHz at each wavelength is...with dDOS system at each wavelength. Red lines are calibrated data and black lines are model fits. Journal of Biomedical Optics 036009-4 March 2017...Grad Fellow in 2009 from the Bioengineering Department at Rice University, where he studied under Rebecca Richards-Kortum. Prior to starting his faculty

  8. Transforming Civil Engineering. Air Force Civil Engineer, Volume 15, Number 1, 2007

    Science.gov (United States)

    2007-01-01

    family would all be worth it if she could help someone and come back here,” said her father, Mr. Stephen Loncki. She was buried with military honors in...responsibility and for getting the job done. He never backed away from the challenge, never backed away from work,” said Mr. Dale Grawe , SrA...Mr. Matthew D. LaPlante, The Salt Lake Tribune; Ms. Jane Carlson and Ms. Rebecca O’Halloran, Galesburg Register-Mail; Mr. Stephen Speckman

  9. Youth Education - Programs / Projects

    OpenAIRE

    2004-01-01

    Christine Bozak: 4-H Steers that Work. Rebecca Brooks: Relationship Skills Education. Travis Burke: Defining Competency in the 4-H Professional’s Job. Holly L. Hays Butler: 4-H at the Indiana School for the Deaf . Kevin D. Chilek: Quality Assurance Program for Youth Livestock Exhibitors. Graham Cochran: Lessons from an Innovative Urban Youth Education Center. Steve Cramer: Use Activities Fun and Humor to Teach Character Education. Annette Devitt: Life on the Farm Project. Janet Edwards: Emot...

  10. Regional plan throughout sectional bioenergy of Castilla y Leon (PBCYL)

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez, R.; Ayuste, R.; Diez, S.; Munoz, M. (Ente Regional de la Energia de Castilla y Leon, Leon (Spain))

    2009-07-01

    The Bioenergy Action Plan of Castilla y Leon (BAPCyL) is a tool of the Regional Government to set up measures for supporting the bioenergy sector. The plan has been elaborated by experts in energy, agriculture, woodlands, residues and economy from the Junta de castilla y Leon (the region government). The BAPCyL designers for 2020, according to European Union: Mobilize local biomass (1.600 ktep). Reach an electrical power of 260 MWe. provide heating for 250.000 people. Substitution of 10% of fossil fuels used in transport. It proposes a strategy with 50 measures and 100 specific actions, from the raw material to the final consumer: Resources: Plan of Mobilization Wood to increase the offer of the resource. Regional Energy crops Program. Complete the use of biogas from dumps. Improve the management of farmer, agricultures and agroofood residues. Inventory all organic residues available. Boost the associations of biomass producers. Users: Planning big projects. Biomass boilers for public buildings. RTDI in equipment, technology and process. Cross measures: Advising for SMEes and professional training. Biomass handbooks. Promotional campaigns. Standardization of biofuels. Regional Observatory for the bioenergy. (orig.)

  11. You Say Potato!

    OpenAIRE

    Gillespie, Elgy

    2001-01-01

    "If we are what we eat, as they are forever telling, then we're mostly potato" sayd travel writer, journalist and enthusiastic cook Elgy Gillespie Now Elgy has drawn on her travel experiences and her love of food to gather over 100 potato recipes from Ireland and around the world" Taken from the back cover. Published by Wolfhound Press Ltd., 68 Mountjoy Square, Dublin in 2001. Illustrated by Rebecca Wildsmith. Cover illustration Eva Byrne, cover photograph Richard Gibson, cover design W...

  12. A systematic review of interventions conducted in clinical or community settings to improve dual-task postural control in older adults

    OpenAIRE

    Agmon M; Belza B; Nguyen HQ; Logsdon RG; Kelly VE

    2014-01-01

    Maayan Agmon,1 Basia Belza,2 Huong Q Nguyen,2,3 Rebecca G Logsdon,2 Valerie E Kelly41The Cheryl Spencer Department of Nursing, Faculty of Social Welfare and Health Studies, University of Haifa, Israel; 2School of Nursing, University of Washington, Seattle, WA, USA; 3Department of Research and Evaluation, Kaiser Permanente, CA, USA; 4School of Medicine, University of Washington, Seattle, WA, USABackground: Injury due to falls is a major problem among older adults. Decrements in dual-task postu...

  13. The SFMOMA AR Game Jam

    DEFF Research Database (Denmark)

    Brin, Sarah; Gangsei, Erica

    2018-01-01

    In the Summer of 2016, Pokémon Go precipitated a surge of new play experiences in museums. Cultural heritage institutions across disciplines were confronted with the sudden ubiquity of augmented reality (AR). Some museums enthusiastically integrated Pokémon into their programs, while some grapple......, and Rebecca Edwards. “Night at the Museum: The 2016 Getty/USC Game Jam.” Blog. The Getty Iris, March 31, 2016. http://blogs.getty.edu/iris/a-night-at-themuseum-the-2016-gettyusc-game-jam/....

  14. MX: Milestone II. Final Environmental Impact Statement. Volume 6. Public Comments

    Science.gov (United States)

    1978-10-06

    8217VPaoli, molyore, ’leming# Daily, Otis, AKrun, Brus , LcKley, "ray, Jos, Id~lia, and Vernon. Thjen tncrc are a nuuber ul CceUCeerleS in tebween witl Ourialz...KS Public Comments VI - 5-101 Grace Eastin Yuma, CO M. H. Eaton Oakley, KS Mr. Dan R. Ebener Dubuque, IA Mr. Tom Eberhart Burlington, CO Elizabeth ...Russell Springs, KS Burlington, CO Rebecca L. Smith Mrs. Elizabeth StevensWinona, KS Potter, NE * r. Ronald L. Smith Mr. Wesley L. Stevens Winona, KS

  15. Lähme, naised / Tiina Kuuler

    Index Scriptorium Estoniae

    Kuuler, Tiina, 1969-

    2008-01-01

    Muusikasündmustest: Rebecca "Inglite pisarad" 10. apr. Tallinnas Toompeal Nelipühi kirikus, "Puhkpilliorkester Tartu 60" 6. apr. Vanemuise kontserdimajas, Singer-Vinger 4. apr. Tallinnas Rock Cafés, "Kolumbus Kris 21" 11. apr. Rock Cafés, "Rock & Roll City" 5. apr. Rock Cafés, Voiceboys 4. apr. Vanemuise kontserdimajas, 5. apr. Jõhvi kontserdimajas ja 6. apr. Estonia kontserdisaalis, "The Musigue Bazaar" 4. apr. Tartus baaris Tige Tikker, Clubarena sünnipäev 4. apr. Tallinnas Mustpeade majas (vt. www.clubarena.com)

  16. Correction to toporek (2014).

    Science.gov (United States)

    2015-01-01

    Reports an error in "Pedagogy of the privileged: Review of Deconstructing Privilege: Teaching and Learning as Allies in the Classroom" by Rebecca L. Toporek (Cultural Diversity and Ethnic Minority Psychology, 2014[Oct], Vol 20[4], 621-622). This article was originally published online incorrectly as a Brief Report. The article authored by Rebecca L. Toporek has been published correctly as a Book Review in the October 2014 print publication (Vol. 20, No. 4, pp. 621-622. http://dx.doi.org/10.1037/a0036529). (The following abstract of the original article appeared in record 2014-42484-006.) Reviews the book, Deconstructing Privilege: Teaching and Learning as Allies in the Classroom edited by Kim A. Case (2013). The purpose of this book is to provide a collection of resources for those teaching about privilege directly, much of this volume may be useful for expanding the context within which educators teach all aspects of psychology. Understanding the history and systems of psychology, clinical practice, research methods, assessment, and all the core areas of psychology could be enhanced by consideration of the structural framework through which psychology has developed and is maintained. The book presents a useful guide for educators, and in particular, those who teach about systems of oppression and privilege directly. For psychologists, this guide provides scholarship and concrete strategies for facilitating students' awareness of multiple dimensions of privilege across content areas. (PsycINFO Database Record (c) 2015 APA, all rights reserved).

  17. Las ruinas y las sombras de Manderley

    Directory of Open Access Journals (Sweden)

    Donapetry Camacho, María

    2010-02-01

    Full Text Available The ruins and the shadows of Manderley explores possible reciprocal interpretative relations between Daphne du Maurier’s novel Rebecca and Alfred Hitchcock’s cinematic version. Some of the relevant aspects considered here are: the treatment of the Derridean “ruins of memory” within the novel and within Hitchcock himself, the differentiation and the confrontation of the protagonist as outsider vis á vis the world of Manderley’s insiders, the iconic and symbolic values of the literary text and its filmic visualization, and the ethical positions implied by the choice or rejection of certain narrative devices in both works.

    Las ruinas y las sombras de Manderley aborda posibles relaciones interpretativas recíprocas entre la novela de Daphne du Maurier Rebecca y la película homónima de Alfred Hitchcock. Algunos de los aspectos que se consideran relevantes en este estudio son: el tratamiento de las “ruinas de la memoria” derridianas dentro de la novela y del propio Hitchcock, la diferenciación y el enfrentamiento de la protagonista “externa” con el mundo de los “internos” de Manderley, los valores icónicos y simbólicos del texto literario y de la visualización fílmica, y las posiciones éticas que implican la elección o el rechazo de ciertos recursos narrativos en ambas obras.

  18. Gene expression responses of paper birch (Betula papyrifera) to elevated CO2 and O3 during leaf maturation and senescence

    International Nuclear Information System (INIS)

    Kontunen-Soppela, Sari; Parviainen, Juha; Ruhanen, Hanna; Brosche, Mikael; Keinaenen, Markku; Thakur, Ramesh C.; Kolehmainen, Mikko; Kangasjaervi, Jaakko; Oksanen, Elina; Karnosky, David F.; Vapaavuori, Elina

    2010-01-01

    Gene expression responses of paper birch (Betula papyrifera) leaves to elevated concentrations of CO 2 and O 3 were studied with microarray analyses from three time points during the summer of 2004 at Aspen FACE. Microarray data were analyzed with clustering techniques, self-organizing maps, K-means clustering and Sammon's mappings, to detect similar gene expression patterns within sampling times and treatments. Most of the alterations in gene expression were caused by O 3 , alone or in combination with CO 2 . O 3 induced defensive reactions to oxidative stress and earlier leaf senescence, seen as decreased expression of photosynthesis- and carbon fixation-related genes, and increased expression of senescence-associated genes. The effects of elevated CO 2 reflected surplus of carbon that was directed to synthesis of secondary compounds. The combined CO 2 + O 3 treatment resulted in differential gene expression than with individual gas treatments or in changes similar to O 3 treatment, indicating that CO 2 cannot totally alleviate the harmful effects of O 3 . - Clustering analysis of birch leaf gene expression data reveals differential responses to O 3 and CO 2 .

  19. Classification of molecular structure images by using ANN, RF, LBP, HOG, and size reduction methods for early stomach cancer detection

    Science.gov (United States)

    Aytaç Korkmaz, Sevcan; Binol, Hamidullah

    2018-03-01

    Patients who die from stomach cancer are still present. Early diagnosis is crucial in reducing the mortality rate of cancer patients. Therefore, computer aided methods have been developed for early detection in this article. Stomach cancer images were obtained from Fırat University Medical Faculty Pathology Department. The Local Binary Patterns (LBP) and Histogram of Oriented Gradients (HOG) features of these images are calculated. At the same time, Sammon mapping, Stochastic Neighbor Embedding (SNE), Isomap, Classical multidimensional scaling (MDS), Local Linear Embedding (LLE), Linear Discriminant Analysis (LDA), t-Distributed Stochastic Neighbor Embedding (t-SNE), and Laplacian Eigenmaps methods are used for dimensional the reduction of the features. The high dimension of these features has been reduced to lower dimensions using dimensional reduction methods. Artificial neural networks (ANN) and Random Forest (RF) classifiers were used to classify stomach cancer images with these new lower feature sizes. New medical systems have developed to measure the effects of these dimensions by obtaining features in different dimensional with dimensional reduction methods. When all the methods developed are compared, it has been found that the best accuracy results are obtained with LBP_MDS_ANN and LBP_LLE_ANN methods.

  20. Cloud Chamber

    DEFF Research Database (Denmark)

    Gfader, Verina

    Cloud Chamber takes its roots in a performance project, titled The Guests 做东, devised by Verina Gfader for the 11th Shanghai Biennale, ‘Why Not Ask Again: Arguments, Counter-arguments, and Stories’. Departing from the inclusion of the biennale audience to write a future folk tale, Cloud Chamber......: fiction and translation and translation through time; post literacy; world picturing-world typing; and cartographic entanglements and expressions of subjectivity; through the lens a social imaginary of worlding or cosmological quest. Art at its core? Contributions by Nikos Papastergiadis, Rebecca Carson...

  1. Who would benefit from memory training? A pilot study examining the ceiling effect of concurrent cognitive stimulation

    OpenAIRE

    Kwok, Timothy CY; Chau, Wai Wang; Yuen, Kenneth SL; Wong, Anita YM; Li, Jessie CY; Shiu, Rebecca YY; Ho, Florence KY

    2011-01-01

    Timothy CY Kwok1,2, Wai Wang Chau1, Kenneth SL Yuen1,3, Anita YM Wong4, Jessie CY Li1, Rebecca YY Shiu4, Florence KY Ho11Jockey Club Centre for Positive Ageing, Hong Kong; 2Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong; 3Laboratory of Neuropsychology, Department of Psychology, University of Hong Kong, Pokfulam, Hong Kong; 4The Hong Kong Chinese Women's Club Madam Wong Chan Sook Ying Memorial Care and Attention Home for the Aged, Hong KongAbstr...

  2. Naturalist Sentimentalism

    DEFF Research Database (Denmark)

    Wohlmann, Anita

    2018-01-01

    This article examines four short stories by the American writer Rebecca Harding Davis (1831-1910), who became a nationally acclaimed writer with the stylistically innovative novella Life in the Iron Mills (1861). Using the double perspective of age studies and ‘naturalist sentimentalism’, the essay...... analyses Davis’s representation of the paradoxes of old age. Davis blends sentimental ideals of sympathy, sacrifice, and hope with naturalist themes of entrapment, the inevitability of decline, and biological determinism. Four short stories by Davis will serve as cases in point: ‘At Noon’ (1887), ‘At...

  3. "My body was my temple": a narrative revealing body image experiences following treatment of a spinal cord injury.

    Science.gov (United States)

    Bailey, K Alysse; Gammage, Kimberley L; van Ingen, Cathy; Ditor, David S

    2017-09-01

    This narrative explores the lived experience of a young woman, Rebecca, and her transitioned body image after sustaining and being treated for a spinal cord injury. Data were collected from a single semi-structured in-depth interview. Rebecca disclosed her transitioned body image experiences after sustaining a spinal cord injury and being treated by medical staff immediately following her injury. Before her injury, she described a holistic body experience and named this experience her "temple". During intensive care in the hospital, she explained her body was treated as an object. The disconnected treatment of her body led to a loss of the private self, as she described her sacred body being stripped away - her "temple" lost and in ruins. Body image may be an overlooked component of health following a spinal cord injury. This narrative emphasizes the importance of unveiling body image experiences after the treatment of a spinal cord injury to medical professionals. Lessons of the importance of considering the transitioned body experiences after a spinal cord injury may help prevent body-related depression and other subsequent health impacts. Recommendations for best practice are provided. Implications for Rehabilitation    Spinal Cord Injury   • A spinal cord injury may drastically change a person's body image, thereby significantly impacting psychological health   • More effective screening for body image within the medical/rehabilitation context is needed to help practitioners recognize distress   • Practitioners should be prepared to refer clients to distress hotlines they may need once released from treatment.

  4. Survival, safety, and prognostic factors for outcome with Regorafenib in patients with metastatic colorectal cancer refractory to standard therapies: results from a multicenter study (REBACCA) nested within a compassionate use program

    International Nuclear Information System (INIS)

    Adenis, Antoine; Fouchardiere, Christelle de la; Paule, Bernard; Burtin, Pascal; Tougeron, David; Wallet, Jennifer; Dourthe, Louis-Marie; Etienne, Pierre-Luc; Mineur, Laurent; Clisant, Stéphanie; Phelip, Jean-Marc; Kramar, Andrew; Andre, Thierry

    2016-01-01

    Randomized trials have shown a survival benefit for regorafenib over placebo in patients with metastatic colorectal cancer (mCRC) that progressed after standard therapies. We evaluated survival and safety outcomes in patients treated with regorafenib in a real-life setting. REBECCA is a cohort study nested within a compassionate use program designed to evaluate survival, safety, and potential prognostic factors for outcome associated with regorafenib in patients with mCRC refractory to standard therapies. Treatment effects according to various patient and tumour characteristics were evaluated using univariate and multivariate Cox proportional hazards regression models. Of 1178 patients in the compassionate use program, 654 were in the full analysis set. Median follow-up was 16.5 months. Median survival was 5.6 months. The 12-month survival rate was 22 %. Survival was independently and unfavourably affected by the following variables: poor performance status, short time from initial diagnosis of metastases to the start of regorafenib, low initial regorafenib dose, >3 metastatic sites, presence of liver metastases, and KRAS mutations. We identified prognostic groups of patients with low, intermediate, and high risk of death, with a median survival of 9.2, 5.2, and 2.5 months, respectively. Five-hundred-twenty-four patients (80 %) experienced at least one regorafenib-related adverse event, most commonly, fatigue, hand-foot skin reaction, diarrhea, anorexia, arterial hypertension, and mucositis. The safety and efficacy profile of regorafenib in REBECCA are similar to those in randomized trials. Our prognostic model identified subgroups of mCRC patients who derived a minimal and maximum benefit from regorafenib. Clinicaltrials.gov: NCT02310477

  5. Hypnotherapy: the salutogenic solution to dealing with phobias.

    Science.gov (United States)

    Williamson, Maria; Gregory, Colette

    2015-05-01

    Evidence suggests that around a quarter of women can suffer from an intense fear of giving birth (tocophobia). This can be costly to these women in terms of enduring negative effects of the increased use of medical interventions associated with tocophobia. Other phobias, such as white coat hypertension, can also be problematic in pregnancy. This article describes the establishment of a hypnotherapy service within the antenatal day assessment unit at East Lancashire Hospitals NHS Trust and recounts a recent case study in which the use of hypnotherapy was employed to help Rebecca, a white coat hypertension sufferer, to successfully manage her condition.

  6. Mänguline ruum : piirideta arhitektuur = Performative Space : the loose boundary of architecture / Rebecca Jones, Nathalie Pozzi

    Index Scriptorium Estoniae

    Jones, Rebecca

    2009-01-01

    Arhitektuurist, mis on dialoogis teiste kunsti- ja eluvormidega. Artikkel on sissejuhatuseks suuremale uurimustööle etendusliku arhitektuuri kontseptsioonist. Autorite vaateid on mõjutanud soome arhitekt Marco Casagrande ja ameerika lavastaja Robert Wilson

  7. Cultivar of Gerbera grown in soil less culture on inert substrates with open and closed systems in comparison with a traditional cultivation on soil in beds; Coltivazione di gerbera in idroponica su substrato con sistema di irrigazione a ciclo aperto e a ciclo chiuso a confronto con la coltivazione tradizionale in cassone su terriccio

    Energy Technology Data Exchange (ETDEWEB)

    Schiavi, A [MIRAAF, Istituto Sperimentale per l` Orticultura (Italy). Sezione di Ascoli Piceno; Venezia, A [Istituto Sperimentale per l` Orticoltura (Italy). Sezione di Montanaso Lomabardo; Martignon, G [Centro Ricerca Ambiente e Materiali, Unita` Calore residuo e Biomasse, Gruppo Agritermia, Milan (Italy)

    1996-01-01

    The aim of the experiment was the evaluation of the yield of several cultivar of gerbera grown in soil less culture on inert substrates with open and closed systems, in comparison with a traditional cultivation on soil in beds. The trial was carried out in the experimental station at Tavazzano (Milan), in a iron plastic greenhouse heated with the waste water discharged by the local thermo electrical power plant. Two inert substrates (rokwool and perlite) were tested in soil less culture both with an open system and a closed system, based on the reuse of the drained nutrient solution. The cultivars Rosula, Pascal, Queen Rebecca, Horizon, Sunspot e Fleur were utilized, grown with a plant density of 10 plants/mq. The trial started in april 1993 and ended in december 1994. The results have pointed out statistically significative differences in the production of cut flower in the growing systems tested. Plants grown in soil less culture with open system gave a number of cut flowers/plant higher both than those grown on soil and with soil less closed system. Agriperlite gave a better commercially yield than rockwool in soil less culture. The distribution of commercial cut flowers in the three category considered (extra, first and second class) was the same for the all thesis; the not marketable production was lower for plant grown on soil than on both the soil less culture systems. With regard to the response of the cultivar, Queen Rebecca and Pascal gave a commercial yield of about 30 cut flowers/plant higher than Rosula, Horizon and Fleur; the cultivar SunSpot showed the lower yield (17 cut flowers/plant).

  8. Scaffolded biology.

    Science.gov (United States)

    Minelli, Alessandro

    2016-09-01

    Descriptions and interpretations of the natural world are dominated by dichotomies such as organism vs. environment, nature vs. nurture, genetic vs. epigenetic, but in the last couple of decades strong dissatisfaction with those partitions has been repeatedly voiced and a number of alternative perspectives have been suggested, from perspectives such as Dawkins' extended phenotype, Turner's extended organism, Oyama's Developmental Systems Theory and Odling-Smee's niche construction theory. Last in time is the description of biological phenomena in terms of hybrids between an organism (scaffolded system) and a living or non-living scaffold, forming unit systems to study processes such as reproduction and development. As scaffold, eventually, we can define any resource used by the biological system, especially in development and reproduction, without incorporating it as happens in the case of resources fueling metabolism. Addressing biological systems as functionally scaffolded systems may help pointing to functional relationships that can impart temporal marking to the developmental process and thus explain its irreversibility; revisiting the boundary between development and metabolism and also regeneration phenomena, by suggesting a conceptual framework within which to investigate phenomena of regular hypermorphic regeneration such as characteristic of deer antlers; fixing a periodization of development in terms of the times at which a scaffolding relationship begins or is terminated; and promoting plant galls to legitimate study objects of developmental biology.

  9. Why developmental niche construction is not selective niche construction: and why it matters.

    Science.gov (United States)

    Stotz, Karola

    2017-10-06

    In the last decade, niche construction has been heralded as the neglected process in evolution. But niche construction is just one way in which the organism's interaction with and construction of the environment can have potential evolutionary significance. The constructed environment does not just select for , it also produces new variation. Nearly 3 decades ago, and in parallel with Odling-Smee's article 'Niche-constructing phenotypes', West and King introduced the 'ontogenetic niche' to give the phenomena of exo genetic inheritance a formal name. Since then, a range of fields in the life sciences and medicine has amassed evidence that parents influence their offspring by means other than DNA (parental effects), and proposed mechanisms for how heritable variation can be environmentally induced and developmentally regulated. The concept of 'developmental niche construction' (DNC) elucidates how a diverse range of mechanisms contributes to the transgenerational transfer of developmental resources. My most central of claims is that whereas the selective niche of niche construction theory is primarily used to explain the active role of the organism in its selective environment, DNC is meant to indicate the active role of the organism in its developmental environment. The paper highlights the differences between the construction of the selective and the developmental niche, and explores the overall significance of DNC for evolutionary theory.

  10. 50 CFR Appendix B to Part 622 - Gulf Areas

    Science.gov (United States)

    2010-10-01

    ... north of Dry Tortugas 24°48.0′ 82°48.0′ 2North of Rebecca Shoal 25°07.5′ 82°34.0′ 3Off Sanibel Island...′ 26Northeast of Port Mansfield 27°00.0′ 96°39.0′ 27East of Port Mansfield 26°44.0′ 96°37.5′ 28Northeast of Port... Dry Tortugas 24°45.5′ 82°41.5′ 2North of Marquesas Keys 24°48.0′ 82°06.5′ 3Off Cape Sable 25°15.0′ 82...

  11. A true politician Rebecca Browning Rankin, municipal reference librarian of the City of New York, 1920-1952

    CERN Document Server

    Seaver, Barry W

    2014-01-01

    "Truly fascinating...highly recommended"--Library Journal; "meticulously documented"--Libraries & Culture; "recommended"--The Australian Library Journal. "Iluminates the history of New York City at a time of dramatic political change."--William E. Leuchtenburg, William Rand Kenan Professor Emeritus, University of North Carolina at Chapel Hill. "must reading"--Roger W. Lotchin, Professor of History, University of North Carolina at Chapel Hill.

  12. Primordial Spirituality

    Directory of Open Access Journals (Sweden)

    Kees Waaijman

    2010-11-01

    Full Text Available This article explores the primordial spirituality of the Bible, as expressed in names, narratives and prayers. It looks at the nomadic families of Abraham and Sarah, Isaac and Rebecca, Jacob, Lea and Rachel, moving around from Mesopotamia via Canaan into Egypt and vice versa (see Gn 11:31–32; 12:4–5; 27:43; 28:10; 29:4; Gn 24 and 29–31. It analyses their experiences, covering the span between birth and death and listens to their parental concerns about education as survival. It also follows their journeys along the margins of the deserts. It shares their community life as it takes shape in mutual solidarity, mercy and compassion.

  13. Sobre machos reales y santos ficticios: Yo no tengo la culpa de haber nacido tan sexy de Eduardo Mendicutti, entre lo global y lo local

    Directory of Open Access Journals (Sweden)

    Dieter Ingenschay

    2011-01-01

    Full Text Available En Yo no tengo la culpa de haber nacido tan sexy (1997, Eduardo Mendicutti cuenta unos episodios del “peregrinaje” de la todavía hermosa transexual Rebecca de Windsor a siete monasterios que visita en busca de la perfección religiosa y de la unión con el Amado divino. El texto despliega su estética camp a través del pastiche de los estilos, dicciones y temas de la lírica mística barroca, sobre todo por las referencias a Las Moradas de Santa Teresa de Ávila, su intertexto directo. A la vez logra describir las consecuencias de la globalización de las prácticas homosexuales y tematizar los rasgos específicos

  14. Alcohol advertising and youth.

    Science.gov (United States)

    Martin, Susan E; Snyder, Leslie B; Hamilton, Mark; Fleming-Milici, Fran; Slater, Michael D; Stacy, Alan; Chen, Meng-Jinn; Grube, Joel W

    2002-06-01

    This article presents the proceedings of a symposium at the 2001 Research Society on Alcoholism meeting in Montreal, Canada. The symposium was organized and chaired by Joel W. Grube. The presentations and presenters were (1) Introduction and background, by Susan E. Martin; (2) The effect of alcohol ads on youth 15-26 years old, by Leslie Snyder, Mark Hamilton, Fran Fleming-Milici, and Michael D. Slater; (3) A comparison of exposure to alcohol advertising and drinking behavior in elementary versus middle school children, by Phyllis L. Ellickson and Rebecca L. Collins; (4) USC health and advertising project: assessment study on alcohol advertisement memory and exposure, by Alan Stacy; and (5) TV beer and soft drink advertising: what young people like and what effects? by Meng-Jinn Chen and Joel W. Grube.

  15. Le rêve communautaire de Marie-Claire Blais. Eschatologie et agapé dans le cycle de 'Soifs'

    Directory of Open Access Journals (Sweden)

    Petr Kyloušek

    2013-01-01

    Full Text Available Marie-Claire Blais seeks to innovate, throughout her career, her 'antimimétique' writing. Her extensive pentalogy - Soifs (1995, Dans la foudre et la lumière (2001, Augustino et le choeur de la destruction (2005, Naissance de Rebecca à l’ère des tourments (2008, Mai au bal des prédateurs (2010 – offers a complex existential questioning of the actual situation of the man. The problem of Evil and Good, which is in the heart of questions and answers, is treated with an original narration, transforming Virginia Woolf’s stream of consciousness. This innovation, however, is rooted in the tradition, namely its baroque poetics and its community orientation, both attached to the affirmation / negation of the catholic heritage that marked Quebec.

  16. Acute respiratory infections in young Ethiopian children

    Directory of Open Access Journals (Sweden)

    Harris RA

    2015-07-01

    Full Text Available Rebecca Arden HarrisDepartment of Family and Social Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USAThe identification of risk factors for acute respiratory infections (ARI is crucial for designing interventions to both minimize transmission and augment the immune response, particularly in Sub-Saharan Africa where poverty-related ARI is still a major cause of preventable death in young children.1 I therefore read with interest Geberetsadik et al’s recent study of the factors associated with ARI in Ethiopian children.2 Their study uses nationally representative data on households and individuals to build a model of the social, demographic, and anthropometric determinants of ARI. A precise understanding of their model, however, requires clarification of several items in their paper.View original paper by Geberetsadik et al.

  17. Use of IUDs for emergency contraception: current perspectives

    Directory of Open Access Journals (Sweden)

    McKay R

    2014-08-01

    Full Text Available Rebecca McKay,1 Lynne Gilbert2 1Department of Obstetrics and Gynaecology, Peterborough City Hospital, Peterborough, Cambridgeshire, United Kingdom; 2Department of Contraception and Sexual Health, Cambridgeshire Community Services NHS Trust, Cambridge, Cambridgeshire, United Kingdom Abstract: Emergency contraception is an essential intervention for the prevention of unplanned pregnancy worldwide. The copper intrauterine device (IUD is highly effective at preventing pregnancy after unprotected sex or contraceptive failure. Unfortunately, its usage in this context is low and far exceeded by hormonal forms of emergency contraception. These have higher failure rates and, unlike the IUD, are not effective post-fertilization. This review aims to summarize the literature surrounding IUD use as emergency contraception, contrast it with the hormonal options, and provide suggestions for increased usage. Keywords: levonorgestrel, ulipristal acetate, copper intrauterine device

  18. An evaluation of a Books on Prescription scheme in a UK public library authority.

    Science.gov (United States)

    Furness, Rebecca; Casselden, Biddy

    2012-12-01

    This article discusses an evaluation of a Books on Prescription (BOP) scheme in a UK public library authority. The research was carried out by Rebecca Furness and submitted as a dissertation for the MSc Information and Library Management to Northumbria University. The dissertation was supervised by Biddy Casselden at Northumbria University and was awarded a distinction. The dissertation identified areas for development for BOP schemes and made specific recommendations that could make the schemes more accessible, enabling significant numbers of people to lead more fulfilling lives. Because this study focuses on mental health and the role that UK public libraries have in supporting well-being, it is a good illustration of the wide-ranging nature of subjects welcomed for the Dissertations into practice feature. © 2012 The authors. Health Information and Libraries Journal © 2012 Health Libraries Group.

  19. Gamma-Ray Bursts Shower the Universe with Metals

    International Nuclear Information System (INIS)

    Hazi, A

    2006-01-01

    According to the results from a Livermore computer model, some of the small change jingling in your pocket contains zinc and copper created in massive gamma-ray bursts (GRBs) that rank as the most impressive light shows in the universe. Livermore astrophysicist Jason Pruet and his colleagues Rebecca Surman and Gail McLaughlin from North Carolina State University (NCSU) reported on their calculations in the February 20, 2004, issue of ''Astrophysical Journal Letters''. They found that GRBs from black holes surrounded by a disk of dense, hot plasma may have contributed heavily to the galactic inventory of elements such as calcium, scandium, titanium, zinc, and copper. ''A typical GRB of this kind briefly outshines all the stars in millions of galaxies combined'', says Pruet. ''Plus it makes about 100 times as much of some common elements as an ordinary supernova''

  20. Christianity and globalisation: An alternative ethical response

    Directory of Open Access Journals (Sweden)

    Retief Müller

    2011-07-01

    Full Text Available This article critically evaluated the role of Christian Ethics in response to globalisation. It showed that ethical critiques of globalisation inevitably fall short when Christianity’s historical contributions to processes of globalisation are neglected or de-emphasised. A Christian Ethics that attempts completely to wash its hands of and disavow globalisation is therefore indicated to be perched on a false premise. In this regard, the author specifically discussed the divergent stances of Max Stackhouse and Rebecca Todd Peters and opted for the former as the more helpful when considered from an interdisciplinary approach. In the final analysis, the author argued that the problem of globalisation might fruitfully be addressed with an ethics that is not averse to bring the various insights of missiology, church history and practical theology to the table, focusing particularly on rituals of reconciliation and forgiveness.

  1. Nuclear Energy Research Initiative (NERI): On-Line Intelligent Self-Diagnostic Monitoring for Next Generation Nuclear Plants - Phase I Annual Report

    International Nuclear Information System (INIS)

    Bond, L.G.; Doctor, S.R.; Gilbert, R.W.; Jarrell, D.B.; Greitzer, F.L.; Meador, R.J.

    2000-01-01

    OAK-B135 This OSTI ID belongs to an IWO and is being released out of the system. The Program Manager Rebecca Richardson has confirmed that all reports have been received. The objective of this project is to design and demonstrate the operation of the real-time intelligent self-diagnostic and prognostic system for next generation nuclear power plant systems. This new self-diagnostic technology is titled, ''On-Line Intelligent Self-Diagnostic Monitoring System'' (SDMS). This project provides a proof-of-principle technology demonstration for SDMS on a pilot plant scale service water system, where a distributed array of sensors is integrated with active components and passive structures typical of next generation nuclear power reactor and plant systems. This project employs state-of-the-art sensors, instrumentation, and computer processing to improve the monitoring and assessment of the power reactor system and to provide diagnostic and automated prognostics capabilities

  2. Enhancement of plant metabolite fingerprinting by machine learning.

    Science.gov (United States)

    Scott, Ian M; Vermeer, Cornelia P; Liakata, Maria; Corol, Delia I; Ward, Jane L; Lin, Wanchang; Johnson, Helen E; Whitehead, Lynne; Kular, Baldeep; Baker, John M; Walsh, Sean; Dave, Anuja; Larson, Tony R; Graham, Ian A; Wang, Trevor L; King, Ross D; Draper, John; Beale, Michael H

    2010-08-01

    Metabolite fingerprinting of Arabidopsis (Arabidopsis thaliana) mutants with known or predicted metabolic lesions was performed by (1)H-nuclear magnetic resonance, Fourier transform infrared, and flow injection electrospray-mass spectrometry. Fingerprinting enabled processing of five times more plants than conventional chromatographic profiling and was competitive for discriminating mutants, other than those affected in only low-abundance metabolites. Despite their rapidity and complexity, fingerprints yielded metabolomic insights (e.g. that effects of single lesions were usually not confined to individual pathways). Among fingerprint techniques, (1)H-nuclear magnetic resonance discriminated the most mutant phenotypes from the wild type and Fourier transform infrared discriminated the fewest. To maximize information from fingerprints, data analysis was crucial. One-third of distinctive phenotypes might have been overlooked had data models been confined to principal component analysis score plots. Among several methods tested, machine learning (ML) algorithms, namely support vector machine or random forest (RF) classifiers, were unsurpassed for phenotype discrimination. Support vector machines were often the best performing classifiers, but RFs yielded some particularly informative measures. First, RFs estimated margins between mutant phenotypes, whose relations could then be visualized by Sammon mapping or hierarchical clustering. Second, RFs provided importance scores for the features within fingerprints that discriminated mutants. These scores correlated with analysis of variance F values (as did Kruskal-Wallis tests, true- and false-positive measures, mutual information, and the Relief feature selection algorithm). ML classifiers, as models trained on one data set to predict another, were ideal for focused metabolomic queries, such as the distinctiveness and consistency of mutant phenotypes. Accessible software for use of ML in plant physiology is highlighted.

  3. Application-driven ground motion prediction equation for seismic hazard assessments in non-cratonic moderate-seismicity areas

    Science.gov (United States)

    Bindi, D.; Cotton, F.; Kotha, S. R.; Bosse, C.; Stromeyer, D.; Grünthal, G.

    2017-09-01

    We present a ground motion prediction equation (GMPE) for probabilistic seismic hazard assessments (PSHA) in low-to-moderate seismicity areas, such as Germany. Starting from the NGA-West2 flat-file (Ancheta et al. in Earthquake Spectra 30:989-1005, 2014), we develop a model tailored to the hazard application in terms of data selection and implemented functional form. In light of such hazard application, the GMPE is derived for hypocentral distance (along with the Joyner-Boore one), selecting recordings at sites with vs30 ≥ 360 m/s, distances within 300 km, and magnitudes in the range 3 to 8 (being 7.4 the maximum magnitude for the PSHA in the target area). Moreover, the complexity of the considered functional form is reflecting the availability of information in the target area. The median predictions are compared with those from the NGA-West2 models and with one recent European model, using the Sammon's map constructed for different scenarios. Despite the simplification in the functional form, the assessed epistemic uncertainty in the GMPE median is of the order of those affecting the NGA-West2 models for the magnitude range of interest of the hazard application. On the other hand, the simplification of the functional form led to an increment of the apparent aleatory variability. In conclusion, the GMPE developed in this study is tailored to the needs for applications in low-to-moderate seismic areas and for short return periods (e.g., 475 years); its application in studies where the hazard is involving magnitudes above 7.4 and for long return periods is not advised.

  4. Nuclear Energy Research Initiative (NERI): On-Line Intelligent Self-Diagnostic Monitoring for Next Generation Nuclear Plants - Phase I Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    L. J. Bond; S. R. Doctor; R. W. Gilbert; D. B. Jarrell; F. L. Greitzer; R. J. Meador

    2000-09-01

    OAK-B135 This OSTI ID belongs to an IWO and is being released out of the system. The Program Manager Rebecca Richardson has confirmed that all reports have been received. The objective of this project is to design and demonstrate the operation of the real-time intelligent self-diagnostic and prognostic system for next generation nuclear power plant systems. This new self-diagnostic technology is titled, ''On-Line Intelligent Self-Diagnostic Monitoring System'' (SDMS). This project provides a proof-of-principle technology demonstration for SDMS on a pilot plant scale service water system, where a distributed array of sensors is integrated with active components and passive structures typical of next generation nuclear power reactor and plant systems. This project employs state-of-the-art sensors, instrumentation, and computer processing to improve the monitoring and assessment of the power reactor system and to provide diagnostic and automated prognostics capabilities.

  5. Analysis of Language Learning Strategies Used by Students of Traffic Technology

    Directory of Open Access Journals (Sweden)

    Violeta Jurkovič

    2005-06-01

    Full Text Available Language learning strategies play a vital role in the language acquisition process, and this includes the realm of ESP at the tertiary level of education. This contribution first defines the concept of language learning strategies and gives a historical background to language learning strategy research. The central section focuses on a comparative analysis of language learning strategies used by first year students of traffic technology at the Faculty of Maritime Studies and Transport in Portorož, University of Ljubljana. The analysis, based on Rebecca Oxford’s “Strategy Inventory for Language Learning”, aims to assess the students’ existing awareness of the process of language acquisition and the learning strategies that they use. Objectives of language teachers should include helping students to raise their awareness of language learning strategies and providing them with contexts for their development. Therefore, the concluding section contains sample ESP teaching materials and student instructions focusing on cognitive language learning strategies.

  6. International Symposium for Thyroid Eye Disease (June 2016, London

    Directory of Open Access Journals (Sweden)

    Natalia Y. Sviridenko

    2017-03-01

    Full Text Available In June 2016, an International Symposium dedicated to the cutting edge research and achievements in Thyroid Eye Disease (TED diagnosis and treatment was held in London. The symposium was organized by the International Thyroid Eye Disease (ITEDs. It was attended EUGOGO, North American Neuro-Ophthalmological Society (NANOS and Orbit Society members. The symposium was attended by leading experts in the field of ophthalmology, orbital surgery and endocrinology: Rebecca S. Bahn, Maarten Mourits, Claudio Marcocci, George Kahaly, Mario Salvi, Antony Weetman, Anja Eckstein, Daniel Rootman, Geoffrey Rose, Robert Goldberg and Susanne Pitz, as well as doctors, specializing in the field of endocrinology, ophthalmology, radiology and other specialties. The symposium program was focused on the discussion of TED pathogenesis, classification and new therapeutic and surgical approaches. TED problems discussed by more than 300 professionals (65% ophthalmologists, 18% ophthalmic surgeons and 17% endocrinologists. North America was represented by 50 delegates. Representation of other continents was not less impressive.

  7. Hommes Fatals: Masculine Destructiveness in Alfred Hitchcock´s Rebecca (1940) and Sam Taylor-Johnson´s Fifty Shades of Grey (2015)

    OpenAIRE

    Barrenetxea Guerekiz, Ane

    2017-01-01

    Femmes fatales have been and are still nowadays represented and labelled as inherently or innately evil figures who, by means of their beauty, lure and seduce men in order to deliberately destroy them. Female deadly figures were treated even in ancient times and in the Bible; even nowadays, after the film noir genre catapulted femmes fatales to fame, different representations of these characters can be seen on screen. Nevertheless, this present dissertation attempts to analyse and debate the ...

  8. Rebecca's in the Dark: A Comparative Study of Problem-Based Learning and Direct Instruction/Experiential Learning in Two 4th-Grade Classrooms

    Science.gov (United States)

    Drake, Kay N.; Long, Deborah

    2009-01-01

    Seeking improved student performance in elementary schools has led educators to advocate inquiry-based teaching approaches, including problem-based learning (PBL). In PBL, students simultaneously develop problem-solving strategies, disciplinary knowledge bases, collaborative skills, and dispositions. Research into the efficacy of PBL in elementary…

  9. LICSS - a chemical spreadsheet in microsoft excel.

    Science.gov (United States)

    Lawson, Kevin R; Lawson, Jonty

    2012-02-02

    Representations of chemical datasets in spreadsheet format are important for ready data assimilation and manipulation. In addition to the normal spreadsheet facilities, chemical spreadsheets need to have visualisable chemical structures and data searchable by chemical as well as textual queries. Many such chemical spreadsheet tools are available, some operating in the familiar Microsoft Excel environment. However, within this group, the performance of Excel is often compromised, particularly in terms of the number of compounds which can usefully be stored on a sheet. LICSS is a lightweight chemical spreadsheet within Microsoft Excel for Windows. LICSS stores structures solely as Smiles strings. Chemical operations are carried out by calling Java code modules which use the CDK, JChemPaint and OPSIN libraries to provide cheminformatics functionality. Compounds in sheets or charts may be visualised (individually or en masse), and sheets may be searched by substructure or similarity. All the molecular descriptors available in CDK may be calculated for compounds (in batch or on-the-fly), and various cheminformatic operations such as fingerprint calculation, Sammon mapping, clustering and R group table creation may be carried out.We detail here the features of LICSS and how they are implemented. We also explain the design criteria, particularly in terms of potential corporate use, which led to this particular implementation. LICSS is an Excel-based chemical spreadsheet with a difference:• It can usefully be used on sheets containing hundreds of thousands of compounds; it doesn't compromise the normal performance of Microsoft Excel• It is designed to be installed and run in environments in which users do not have admin privileges; installation involves merely file copying, and sharing of LICSS sheets invokes automatic installation• It is free and extensibleLICSS is open source software and we hope sufficient detail is provided here to enable developers to add their

  10. Pleural mesothelioma: management updates and nursing initiatives to improve patient care

    Directory of Open Access Journals (Sweden)

    Lehto RH

    2014-05-01

    Full Text Available Rebecca H LehtoCollege of Nursing, Michigan State University, East Lansing, MI, USAAbstract: Malignant pleural mesothelioma is a relatively rare but aggressive malignancy that is primarily associated with occupational asbestos exposure. While treatment options for mesothelioma have expanded, the disease carries a poor prognosis, with a median of 8 months to 1 year of survival postdiagnosis. This article synthesizes current disease-management practices, including the diagnostic workup, treatment modalities, emerging therapies, and symptom management, and identifies comprehensive nursing strategies that result in the best care based on updated evidence. Multidisciplinary coordination, palliative care initiation, survivorship, and end-of-life care are discussed. Findings may be applied in clinical environments as a resource to help nurses better understand treatment options and care for patients facing malignant pleural mesothelioma. Recommendations for future research are made to move nursing science forward and to improve patient well-being and health-related quality-of-life outcomes for patients and their family members.Keywords: pleural mesothelioma, cancer, symptom management, evidence-based care

  11. Rezension zu: Rebecca Pates, Daniel Schmidt: Die Verwaltung der Prostitution. Eine vergleichende Studie am Beispiel deutscher, polnischer und tschechischer Kommunen. Bielefeld: transcript Verlag 2009.

    Directory of Open Access Journals (Sweden)

    Jenny Künkel

    2009-09-01

    Full Text Available Die aus dem Forschungsprojekt ‚Verwaltung der Prostitution‘ an der Universität Leipzig heraus entstandene Publikation geht der Frage nach, welche Problemdefinitionen, Kategorisierungen und Wissensbestände lokale Verwaltungsakteure/-innen in Deutschland, Polen und Tschechien der Prostitutionsregulierung zugrunde legen. Die Studie zeigt, dass teilautonomes Verwaltungshandeln Recht nicht nur umsetzt, sondern auch produziert. Durch den Fokus auf die lokale Ebene der Prostitutionsregulierung und durch den staatsethnographischen Zugang ist die Monographie in zweierlei Hinsicht innovativ. Lediglich etwas mehr Informationen zum methodischen Vorgehen sowie ein expliziteres Aufgreifen der theoretischen Konzepte bei der Aufbereitung des empirischen Materials wären wünschenswert gewesen.

  12. Slavery, antislavery, freedom

    Directory of Open Access Journals (Sweden)

    Bridget Brereton

    2002-01-01

    Full Text Available [First paragraph] Empire and Antislavery: Spain, Cuba, and Puerto Rico, 1833-1874. CHRISTOPHER SCHMIDT-NOWARA. Pittsburgh PA: University of Pittsburgh Press, 1999. xv + 239 pp. (Cloth US$ 50.00, Paper US$ 22.95 Beyond Slavery: Explorations of Race, Labor, and Citizenship in Postemancipation Societies. FREDERICK COOPER, THOMAS C. HOLT & REBECCA J. SCOTT. Chapel Hill: University of North Carolina Press, 2000. xiii + 198 pp. (Cloth US$ 34.95, Paper US$ 15.95 From Slavery to Freedom: Comparative Studies in the Rise andFall of Atlantic Slavery. SEYMOUR DRESCHER. New York: New York University Press, 1999. xxv + 454 pp. (Cloth US$ 45.00 Terms of Labor: Slavery, Serfdom, and Free Labor. STANLEY L. ENGERMAN (ed.. Stanford CA: Stanford University Press, 1999. vi + 350 pp. (Cloth US$ 55.00 These four books explore antislavery movements in the Atlantic world, and consider some of the consequences of abolition in postemancipation societies. They are immensely rich studies which engage one of the liveliest areas of enquiry in modern historiography - the transition from slavery to freedom in New World societies - and which represent U.S. historical scholarship at its finest. Each falls into a different category of academic publication.

  13. The principle of procreative beneficence: old arguments and a new challenge.

    Science.gov (United States)

    Hotke, Andrew

    2014-06-01

    In the last ten years, there have been a number of attempts to refute Julian Savulescu's Principle of Procreative Beneficence; a principle which claims that parents have a moral obligation to have the best child that they can possibly have. So far, no arguments against this principle have succeeded at refuting it. This paper tries to explain the shortcomings of some of the more notable arguments against this principle. I attempt to break down the argument for the principle and in doing so, I explain what is needed to properly refute it. This helps me show how and why the arguments of Rebecca Bennett, Sarah Stoller and others fail to refute the principle. Afterwards, I offer a new challenge to the principle. I attack what I understand to be a fundamental premise of the argument, a premise which has been overlooked in the literature written about this principle. I argue that there is no reason to suppose, as Savulescu does, that morality requires us to do what we have most reason to do. If we reject this premise, as I believe we have reason to do, the argument for Procreative Beneficence fails. © 2012 John Wiley & Sons Ltd.

  14. Remapping Capricornia: Xavier Herbert’s Cosmopolitan Imagination

    Directory of Open Access Journals (Sweden)

    Ellen Smith

    2017-11-01

    Full Text Available Since its publication in 1938 critics have generally read Xavier Herbert’s Capricornia as a nationalist novel, even when its nationalism is seen to be structured by contradiction. But little attention has been given to the ways in which Herbert’s complex, multifarious and heteroglossic novel exceeds and challenges the very possibility of coherent national space and a coherent national story. This essay considers moments and spaces in Herbert’s novel where the national is displaced and unravelled. Drawing on Rebecca Walkowitz’s idea of cosmopolitan style and Suvendrini Perera’s work on Australia’s insular imagination I identify a critical cosmopolitanism that inheres in the novel’s geographical imagination and its literary form, particularly the narrative voice which retains a critical distance from the nationalist sensibility of various characters and plot lines, performing a detached and restless homelessness that I identify with the cosmopolitan. Ultimately I ask how the novel’s spatial and environmental imagination displaces its nationalist agenda, making space for a different kind of social imagination—one that does not confine itself to the terms of the nation or organise itself around a central figure for the nation.

  15. Effects of maternal obesity on early and long-term outcomes for offspring

    Directory of Open Access Journals (Sweden)

    Stirrat LI

    2014-03-01

    Full Text Available Laura I Stirrat,1,2 Rebecca M Reynolds2,3 1Medical Research Council Centre for Reproductive Health, Queens Medical Research Institute, University of Edinburgh, Edinburgh, UK; 2Tommy's Centre for Maternal and Fetal Health, Queens Medical Research Institute, University of Edinburgh, Edinburgh, UK; 3Endocrinology Unit, University/British Heart Foundation Centre for Cardiovascular Science, Queens Medical Research Institute, University of Edinburgh, Edinburgh, UK Abstract: The prevalence of maternal obesity has increased significantly in recent years, and obesity is currently the most common comorbidity of pregnancy. Pregnancies of obese women are often defined as "high-risk" for the purposes of clinical care, with many well documented risks to the mother and developing baby. Maternal physiology and metabolism is dysregulated in the context of obesity, which may contribute to some of the adverse outcomes during pregnancy. Furthermore, maternal obesity has been hypothesized to cause harmful effects for the developing baby through "early life programming." This review will examine evidence from human studies for outcomes of offspring from obese women during pregnancy, during labor, during the neonatal period, and later in life. Keywords: pregnancy, short-term, physiology, metabolism, early life programming, neonatal complications, adverse intrauterine environment

  16. Estrogens of multiple classes and their role in mental health disease mechanisms

    Directory of Open Access Journals (Sweden)

    Cheryl S Watson

    2010-06-01

    Full Text Available Cheryl S Watson1, Rebecca A Alyea1, Kathryn A Cunningham2, Yow-Jiun Jeng11Department of Biochemistry and Molecular Biology, 2Department of Pharmacology and Toxicology, Univ of Texas Medical Branch, Galveston, TX, USAAbstract: Gender and sex hormones can influence a variety of mental health states, including mood, cognitive development and function, and vulnerability to neurodegenerative diseases and brain damage. Functions of neuronal cells may be altered by estrogens depending upon the availability of different physiological estrogenic ligands; these ligands and their effects vary with life stages, the genetic or postgenetic regulation of receptor levels in specific tissues, or the intercession of competing nonphysiological ligands (either intentional or unintentional, beneficial to health or not. Here we review evidence for how different estrogens (physiological and environmental/dietary, acting via different estrogen receptor subtypes residing in alternative subcellular locations, influence brain functions and behavior. We also discuss the families of receptors and transporters for monoamine neurotransmitters and how they may interact with the estrogenic signaling pathways.Keywords: estrogen receptor α, estrogen receptor β, GPR30, GPER, xenoestrogens, phytoestrogens, transporters, brain function, neurotransmitter receptors

  17. Taxonomy, systematics and biology of the Australian halotolerant wolf spider genus Tetralycosa (Araneae: Lycosidae: Artoriinae

    Directory of Open Access Journals (Sweden)

    Volker W. Framenau

    2017-07-01

    Full Text Available The Australian wolf spider genus Tftralycosa Roewer, 1960, with Lycosa meracula Simon, 1909 (junior synonym of Lycosa oraria L. Koch, 1877 as type species, is revised to include 13 species, eight of which are described as new here: Tetralycosa adarca sp. nov., T. alteripa (McKay, 1976, T. arabanae Framenau, Gotch & Austin, 2006, T. baudinettei sp. nov., T. caudex sp. nov., T. eyrei (Hickman, 1944, T. floundersi sp. nov., T. halophila sp. nov., T. oraria (L. Koch, 1876, T. orariola sp. nov., T. williamsi sp. nov., T. wundurra (McKay, 1979 comb. nov. and T. rebecca sp. nov. Members of Tetralycosa are halotolerant, exclusively inhabiting saline environments such as coastal beaches, and mound springs, clay pans and salt lakes in the Australian interior. A phylogenetic analysis of the genus identified a monophyletic clade of eight species that live permanently on the barren surface of salt lakes suggesting a single radiation into this extremely inhospitable habitat. Some of these Tetralycosa species are currently known from single salt lakes only and with increasing disturbances of these systems by mining, agriculture and recreational use, research effort should be increased to study their ecology and conservation status.

  18. How Normal is Our Solar System?

    Science.gov (United States)

    Kohler, Susanna

    2015-10-01

    To date, weve discovered nearly 2000 confirmed exoplanets, as well as thousands of additional candidates. Amidst this vast sea of solar systems, how special is our own? A new study explores the answer to this question.Analyzing DistributionsKnowing whether our solar system is unique among exoplanetary systems can help us to better understand future observations of exoplanets. Furthermore, if our solar system is typical, this allows us to be optimistic about the possibility of life existing elsewhere in the universe.In a recent study, Rebecca Martin (University of Nevada, Las Vegas) and Mario Livio (Space Telescope Science Institute) examine how normal our solar system is, by comparing the properties of our planets to the averages obtained from known exoplanets.Comparing PropertiesSo how do we measure up?Densities of planets as a function of their mass. Exoplanets (N=287) are shown in blue, planets in our solar system are shown in red. [MartinLivio 2015]Planet masses and densitiesThose of the gas giants in our solar system are pretty typical. The terrestrial planets are on the low side for mass, but thats probably a selection effect: its very difficult to detect low-mass planets.Age of the solar systemRoughly half the stars in the disk of our galaxy are younger than the Sun, and half are older. Were definitely not special in age.Orbital locations of the planetsThis is actually a little strange: our solar system is lacking close-in planets. All of our planets, in fact, orbit at a distance that is larger than the mean distance observed in exoplanetary systems. Again, however, this might be a selection effect at work: its easier to detect large planets orbiting very close to their stars.Eccentricities of the planets orbitsOur planets are on very circular orbits and that actually makes us somewhat special too, compared to typical exoplanet systems. There is a possible explanation though: eccentricity of orbits tends to decrease with more planets in the system. Because

  19. RESEÑAS - 1. CONSENT OF THE NETWORKED. The Worldwide Struggle for Internet Freedom

    Directory of Open Access Journals (Sweden)

    Ruth Ainhoa de Frutos García

    2012-12-01

    Full Text Available La periodista e investigadora del Berkman Center for Internet and Society de la Universidad de Harvard Rebecca MacKinnon plantea en el libro Consent of the Networked. The Worldwide Struggle for Internet Freedom la necesidad que tienen los usuarios de internet de tomar conciencia y reaccionar sobre las violaciones de derechos humanos ligados a nuestro uso de internet que utilizan gobiernos y empresas.La gobernanza de internet, entendida como el derecho de los llamados ciudadanos digitales de influir en las decisiones políticas y corporativas a través de un consentimiento expreso, se describe a través de catorce capítulos divididos en cinco grandes capítulos: interrupciones, control 2.0, desafíos de la democracia, soberanos del ciberespacio y ¿qué se debe hacer?Tras exponer su análisis crítico sobre la situación mundial actual de las prácticas empresariales y los controles gubernamentales, MacKinnon detalla posibles soluciones para empoderar a los usuarios de internet a través de 294 páginas.La creadora de la iniciativa ciudadana Global Voices anima a los jóvenes a tomar el testigo de esta importante lucha y asumir el liderazgo frente a los poderes empresariales y gubernamentales.

  20. Current perspectives on the etiology and manifestation of the "silent" component of the Female Athlete Triad

    Directory of Open Access Journals (Sweden)

    Mallinson RJ

    2014-05-01

    Full Text Available Rebecca J Mallinson, Mary Jane De SouzaDepartment of Kinesiology, Women's Health and Exercise Laboratory in Noll Laboratory, Pennsylvania State University, University Park, PA, USAAbstract: The Female Athlete Triad (Triad represents a syndrome of three interrelated conditions that originate from chronically inadequate energy intake to compensate for energy expenditure; this environment results in insufficient stored energy to maintain physiological processes, a condition known as low energy availability. The physiological adaptations associated with low energy availability, in turn, contribute to menstrual cycle disturbances. The downstream effects of both low energy availability and suppressed estrogen concentrations synergistically impair bone health, leading to low bone mineral density, compromised bone structure and microarchitecture, and ultimately, a decrease in bone strength. Unlike the other components of the Triad, poor bone health often does not have overt symptoms, and therefore develops silently, unbeknownst to the athlete. Compromised bone health among female athletes increases the risk of fracture throughout the lifespan, highlighting the long-term health consequences of the Triad. The purpose of this review is to examine the current state of Triad research related to the third component of the Triad, ie, poor bone health, in an effort to summarize what we know, what we are learning, and what remains unknown.Keywords: female athlete Triad, bone health, treatment

  1. High mass and spatial resolution mass spectrometry imaging of Nicolas Poussin painting cross section by cluster TOF-SIMS.

    Science.gov (United States)

    Noun, M; Van Elslande, E; Touboul, D; Glanville, H; Bucklow, S; Walter, P; Brunelle, A

    2016-12-01

    The painting Rebecca and Eliezer at the Well, which hangs in the Fitzwilliam Museum, Cambridge, UK, is possibly one of the last figure painting executed by Nicolas Poussin at the very end of his life and is usually dated to the early 1660s. In this perspective special feature, Philippe Walter, Alain Brunelle and colleagues give new insights on the artist's working methods by a careful stateof-the-art imaging ToF-SIMS study of one sample taken on the edge of the painting. This approach allowed for the identification of the pigments used in the painting, their nature and components and those of the ground and preparatory layers, with the identification of the binder(s) and possible other additions of organic materials such as glue. This study paves the way to a wider use of ToF-SIMS for the analysis of ancient cultural heritage artefacts. Dr. Walter is the Director of the Molecular and Structural Archeology Laboratory (Université Pierre et Marie Curie, Paris, France). Dr. Brunelle is Head of the Mass Spectrometry Laboratory at the Institut de Chimie des Substances Naturelles (CNRS, Gif-sur-Yvette, France). Their long standing collaboration has led to several seminal publications on the analysis of ancient artefacts by mass spectrometry. Copyright © 2016 John Wiley & Sons, Ltd.

  2. Internal contamination: what challenges for tomorrow? Proceedings of the Research and Health Section technical day

    International Nuclear Information System (INIS)

    Berard, Philippe; Lecoix, Geraldine; Menetrier, Florence; Menetrier, Florence; Leiterer, Alexandra; Gremy, Olivier; Mougnard, Philippe; Gonin, Michele; Paquet, Francois; Davesne, Estelle; Bertho, Jean-Marc; Metivier, Henri; Abergel, Rebecca

    2015-10-01

    The Research and Health Section of the French Society of Radiation Protection (SFRP) organized a technical meeting on the radiation protection aspects of dismantlement, from the dismantling work to the risk, the measurement of body contamination, the potentially harmful health effects, the available medical treatments, the actual needs and the developments in progress. This document brings together the abstracts and the presentations (slides) of the different talks given at the meeting: 1 - Situation: what radionuclides, what situations? (Philippe BERARD, CEA); 2 - Dismantling workplace experience feedback with internal contamination hazard (Philippe MOUGNARD, AREVA); 3 - Experience feedback on internal exposure monitoring at power plants in France (Michele GONIN, EDF); 4 - Evolution of routine and intervention measurement methods (Geraldine LECOIX, CEA); 5 - Evolution of radiation dose calculation models (Francois PAQUET, IRSN); 6 - Taking uncertainties into account in internal contamination monitoring protocols (Estelle DAVESNE, IRSN); 7 - Radionuclides behaviour and effects in men (Florence MENETRIER, CEA); 8 - The plutonium case (Henri METIVIER, SFRP); 9 - Cesium-137 and internal contamination: status and perspectives (Jean-Marc BERTHO, IRSN); 10 - Iodine and thyroid (Florence MENETRIER, CEA); 11 - Actual treatments and research pathways (Alexandra LEITERER, CEA); 12 - Radionuclide contamination treatment: new developments in the US (Rebecca ABERGEL, Berkeley USA); 13 - Internal contaminations treatment: French recent effort for its improvement (Olivier GREMY, CEA)

  3. Life and Death on the Pulse Dance Floor: Transglocal Politics and Erasure of the Latinx in the History of Queer Dance Culture

    Directory of Open Access Journals (Sweden)

    Tim Lawrence

    2016-11-01

    Full Text Available Although the dominant response of politicians, journalists and campaign groups to Omar Mateen’s 12 June 2016 massacre of forty-nine people at the Pulse nightclub in Orlando revolved around the repetition of already established arguments about terrorism, this article will outline how the massacre amounted to a specific attack on the Latinx community. It will also argue that, although distinctive, the discursive erasure of the specifically queer Latinx finds a partial echo in the way that Latin culture has been marginalised in writing on dance culture. An outline map of the somewhat opaque Latinx contribution will be offered as a small tribute to those who have lived for and now died on the Latinx dance floor. The account of the dancers who gathered at Pulse, the music they danced to, and the unstable, marginalised and dynamic networks of musicians, dancers and party spaces that preceded them will be considered within J. Blake Scott and Rebecca Dingo’s (2012 evocation of the “transglocal”. If transglocal encounters “can generate new meanings and subject positions” (Blake Scott and Dingo: 7, so the dancers at Pulse can be seen to have moved resourcefully, dynamically and creatively between the local and the transnational as they sought out new modes of expression and community in a darkening global terrain.

  4. Who would benefit from memory training? A pilot study examining the ceiling effect of concurrent cognitive stimulation

    Directory of Open Access Journals (Sweden)

    Kwok TCY

    2011-03-01

    Full Text Available Timothy CY Kwok1,2, Wai Wang Chau1, Kenneth SL Yuen1,3, Anita YM Wong4, Jessie CY Li1, Rebecca YY Shiu4, Florence KY Ho11Jockey Club Centre for Positive Ageing, Hong Kong; 2Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong; 3Laboratory of Neuropsychology, Department of Psychology, University of Hong Kong, Pokfulam, Hong Kong; 4The Hong Kong Chinese Women's Club Madam Wong Chan Sook Ying Memorial Care and Attention Home for the Aged, Hong KongAbstract: Diverse effects of memory training were observed in the literature. One possible factor is the amount of concurrent cognitive training received during the training program. In this pilot study, we recruited 24 elderly adults with or without concurrent cognitive stimulations to attend a memory-training program. Findings suggested that elderly people without concurrent cognitive stimulation could benefit from a memory-training program in the form of improved initiation and memory functioning. Self-rated quality of life measure also showed improvements alongside the cognitive benefits. Elderly people with regular concurrent cognitive stimulation, on the other hand, seemed to plateau in their level of performance and did not show any significant change. Our preliminary findings suggested nonlinear concurrent cognitive stimulation in the elderly.Keywords: memory training, cognitive training, dementia, Chinese, elderly 

  5. Anxiety in adolescents: Update on its diagnosis and treatment for primary care providers

    Directory of Open Access Journals (Sweden)

    Siegel RS

    2011-12-01

    Full Text Available Rebecca S Siegel, Daniel P DicksteinPediatric Mood, Imaging, and NeuroDevelopment Program, EP Bradley Hospital, East Providence, RI, USAAbstract: Anxiety disorders are the most prevalent mental health concern facing adolescents today, yet they are largely undertreated. This is especially concerning given that there are fairly good data to support an evidence-based approach to the diagnosis and treatment of anxiety, and also that untreated, these problems can continue into adulthood, growing in severity. Thus, knowing how to recognize and respond to anxiety in adolescents is of the utmost importance in primary care settings. To that end, this article provides an up-to-date review of the diagnosis and treatment of anxiety disorders geared towards professionals in primary care settings. Topics covered include subtypes, clinical presentation, the etiology and biology, effective screening instruments, evidence-based treatments (both medication and therapy, and the long-term prognosis for adolescents with anxiety. Importantly, we focus on the most common types of anxiety disorders, often known as phobias, which include generalized anxiety disorder, social anxiety/social phobia, separation anxiety disorder, panic disorder, and specific phobias. In summary, anxiety is a common psychiatric problem for adolescents, but armed with the right tools, primary care providers can make a major impact.Keywords: anxiety disorders, adolescents, presentation, etiology, assessment, treatment, primary care

  6. William Horner Andrews (1887-1953)- first professor of physiology at Onderstepoort.

    Science.gov (United States)

    Verwoerd, D W; Andrews, W J H

    2011-03-01

    W H Andrews qualified as a veterinarian in London in 1908 and was recruited soon after, in 1909, by Sir Arnold Theiler to join the staff of the newly established veterinary laboratory at Onderstepoort. After initial studies on the treatment of trypanosomosis and on snake venoms he was deployed by Theiler in 1911 to start research on lamsiekte (botulism)at a field station on the farm Kaffraria near Christiana, where he met and married his wife Doris. After a stint as Captain in the SA Veterinary Corps during World War I he succeeded D T Mitchell as head of the Allerton Laboratory in 1918, where he excelled in research on toxic plants, inter alia identifying Matricaria nigellaefolia as the cause of staggers in cattle. When the Faculty of Veterinary Science was established in 1920 he was appointed as the first Professor of Physiology. After the graduation of the first class in 1924, and due to health problems, he returned to the UK, first to the Royal Veterinary College and then to the Weybridge Veterinary Laboratories of which he became Director in 1927. After his retirement in 1947 he returned to South Africa as a guest worker at Onderstepoort where he again became involved in teaching physiology when Prof. Quin unexpectedly died in 1950. Andrews died in Pretoria in 1953 and was buried in the Rebecca Street Cemetery.

  7. Investigation into Practical Implementations of a Zero Knowledge Protocol.

    Energy Technology Data Exchange (ETDEWEB)

    Marleau, Peter [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Krentz-Wee, Rebecca E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-02-01

    In recent years, the concept of Zero Knowledge Protocols (ZKP) as a useful approach to nuclear warhead verification has become increasingly popular. Several implementations of ZKP have been proposed, driving technology development toward proof of concept demonstrations. Whereas proposed implementations seem to fall within the general class of template-based techniques, all physical implementations of ZKPs proposed to date have a complication: once the instrumentation is prepared, it is no longer authenticatable; the instrument physically contains sensitive information. In this work we explore three different concepts that may offer more authenticatable and practical ZKP implementations and evaluate the sensitive information that may be at risk when doing so: sharing a subset of detector counts in a preloaded image (with spatial information removed), real-time image subtraction, and a new concept, CONfirmation using a Fast-neutron Imaging Detector with Anti-image NULL-positive Time Encoding (CONFIDANTE). CONFIDANTE promises to offer an almost ideal implementation of ZKP: a positive result is indicated by a constant rate at all times enabling the monitoring party the possibility of full access to the instrument before, during, and after confirmation. A prototype of CONFIDANTE was designed, built, and its performance evaluated in a series of measurements of several objects including a set of plutonium dioxide Hemispheres. Very encouraging results proving feasibility are presented. 1 Rebecca is currently a graduate student in Nuclear Engineering at UC Berkeley

  8. Innovative fertility preservation strategies and programs for young adults with cancer

    Directory of Open Access Journals (Sweden)

    Johnson RH

    2016-01-01

    Full Text Available Rebecca H Johnson Division of Pediatric Hematology/Oncology, Department of Pediatrics, Mary Bridge Hospital, MultiCare Health System, Tacoma, WA, USA Abstract: Preservation of fertility is a key issue for young adults newly diagnosed with cancer. Up to 90% of cancer patients under the age of 45 are at risk for fertility impairment following cancer therapy. Cancer patients who are not offered fertility preservation (FP and those who become infertile following therapy may experience long-term psychosocial distress. This review summarizes the numerous effective strategies for preserving fertility, including sperm banking, electroejaculation, and testicular sperm extraction in males and cryopreservation of embryos or oocytes in females. This paper also highlights novel methods currently in development, such as gonadal tissue cryopreservation and in vitro maturation of gametes. In women, anti-Mullerian hormone is emerging as an accurate marker of ovarian reserve, and the use of gonadotropin releasing hormone analogs to protect fertility is increasingly well validated. Although national guidelines mandate FP counseling and referral prior to the start of cancer therapy for patients with reproductive potential, only a minority of young cancer patients in the USA currently take steps to preserve fertility prior to the start of therapy. Some cancer centers across the USA are developing institutional strategies to support FP, resulting in increased utilization of fertility services by newly diagnosed cancer patients. Keywords: young adult, cancer, fertility preservation, program, oocyte, sperm

  9. WE-EF-BRD-03: I Want It Now!: Advances in MRI Acquisition, Reconstruction and the Use of Priors to Enable Fast Anatomic and Physiologic Imaging to Inform Guidance and Adaptation Decisions

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Y. [Mayo Clinic Arizona (United States)

    2015-06-15

    MRI-guided treatment is a growing area of medicine, particularly in radiotherapy and surgery. The exquisite soft tissue anatomic contrast offered by MRI, along with functional imaging, makes the use of MRI during therapeutic procedures very attractive. Challenging the utility of MRI in the therapy room are many issues including the physics of MRI and the impact on the environment and therapeutic instruments, the impact of the room and instruments on the MRI; safety, space, design and cost. In this session, the applications and challenges of MRI-guided treatment will be described. The session format is: Past, present and future: MRI-guided radiotherapy from 2005 to 2025: Jan Lagendijk Battling Maxwell’s equations: Physics challenges and solutions for hybrid MRI systems: Paul Keall I want it now!: Advances in MRI acquisition, reconstruction and the use of priors to enable fast anatomic and physiologic imaging to inform guidance and adaptation decisions: Yanle Hu MR in the OR: The growth and applications of MRI for interventional radiology and surgery: Rebecca Fahrig Learning Objectives: To understand the history and trajectory of MRI-guided radiotherapy To understand the challenges of integrating MR imaging systems with linear accelerators To understand the latest in fast MRI methods to enable the visualisation of anatomy and physiology on radiotherapy treatment timescales To understand the growing role and challenges of MRI for image-guided surgical procedures My disclosures are publicly available and updated at: http://sydney.edu.au/medicine/radiation-physics/about-us/disclosures.php.

  10. WE-EF-BRD-01: Past, Present and Future: MRI-Guided Radiotherapy From 2005 to 2025

    Energy Technology Data Exchange (ETDEWEB)

    Lagendijk, J. [University Medical Center Utrecht (Netherlands)

    2015-06-15

    MRI-guided treatment is a growing area of medicine, particularly in radiotherapy and surgery. The exquisite soft tissue anatomic contrast offered by MRI, along with functional imaging, makes the use of MRI during therapeutic procedures very attractive. Challenging the utility of MRI in the therapy room are many issues including the physics of MRI and the impact on the environment and therapeutic instruments, the impact of the room and instruments on the MRI; safety, space, design and cost. In this session, the applications and challenges of MRI-guided treatment will be described. The session format is: Past, present and future: MRI-guided radiotherapy from 2005 to 2025: Jan Lagendijk Battling Maxwell’s equations: Physics challenges and solutions for hybrid MRI systems: Paul Keall I want it now!: Advances in MRI acquisition, reconstruction and the use of priors to enable fast anatomic and physiologic imaging to inform guidance and adaptation decisions: Yanle Hu MR in the OR: The growth and applications of MRI for interventional radiology and surgery: Rebecca Fahrig Learning Objectives: To understand the history and trajectory of MRI-guided radiotherapy To understand the challenges of integrating MR imaging systems with linear accelerators To understand the latest in fast MRI methods to enable the visualisation of anatomy and physiology on radiotherapy treatment timescales To understand the growing role and challenges of MRI for image-guided surgical procedures My disclosures are publicly available and updated at: http://sydney.edu.au/medicine/radiation-physics/about-us/disclosures.php.

  11. WE-EF-BRD-04: MR in the OR: The Growth and Applications of MRI for Interventional Radiology and Surgery

    Energy Technology Data Exchange (ETDEWEB)

    Fahrig, R. [Stanford University (United States)

    2015-06-15

    MRI-guided treatment is a growing area of medicine, particularly in radiotherapy and surgery. The exquisite soft tissue anatomic contrast offered by MRI, along with functional imaging, makes the use of MRI during therapeutic procedures very attractive. Challenging the utility of MRI in the therapy room are many issues including the physics of MRI and the impact on the environment and therapeutic instruments, the impact of the room and instruments on the MRI; safety, space, design and cost. In this session, the applications and challenges of MRI-guided treatment will be described. The session format is: Past, present and future: MRI-guided radiotherapy from 2005 to 2025: Jan Lagendijk Battling Maxwell’s equations: Physics challenges and solutions for hybrid MRI systems: Paul Keall I want it now!: Advances in MRI acquisition, reconstruction and the use of priors to enable fast anatomic and physiologic imaging to inform guidance and adaptation decisions: Yanle Hu MR in the OR: The growth and applications of MRI for interventional radiology and surgery: Rebecca Fahrig Learning Objectives: To understand the history and trajectory of MRI-guided radiotherapy To understand the challenges of integrating MR imaging systems with linear accelerators To understand the latest in fast MRI methods to enable the visualisation of anatomy and physiology on radiotherapy treatment timescales To understand the growing role and challenges of MRI for image-guided surgical procedures My disclosures are publicly available and updated at: http://sydney.edu.au/medicine/radiation-physics/about-us/disclosures.php.

  12. WE-EF-BRD-02: Battling Maxwell’s Equations: Physics Challenges and Solutions for Hybrid MRI Systems

    Energy Technology Data Exchange (ETDEWEB)

    Keall, P. [University of Sydney (Australia)

    2015-06-15

    MRI-guided treatment is a growing area of medicine, particularly in radiotherapy and surgery. The exquisite soft tissue anatomic contrast offered by MRI, along with functional imaging, makes the use of MRI during therapeutic procedures very attractive. Challenging the utility of MRI in the therapy room are many issues including the physics of MRI and the impact on the environment and therapeutic instruments, the impact of the room and instruments on the MRI; safety, space, design and cost. In this session, the applications and challenges of MRI-guided treatment will be described. The session format is: Past, present and future: MRI-guided radiotherapy from 2005 to 2025: Jan Lagendijk Battling Maxwell’s equations: Physics challenges and solutions for hybrid MRI systems: Paul Keall I want it now!: Advances in MRI acquisition, reconstruction and the use of priors to enable fast anatomic and physiologic imaging to inform guidance and adaptation decisions: Yanle Hu MR in the OR: The growth and applications of MRI for interventional radiology and surgery: Rebecca Fahrig Learning Objectives: To understand the history and trajectory of MRI-guided radiotherapy To understand the challenges of integrating MR imaging systems with linear accelerators To understand the latest in fast MRI methods to enable the visualisation of anatomy and physiology on radiotherapy treatment timescales To understand the growing role and challenges of MRI for image-guided surgical procedures My disclosures are publicly available and updated at: http://sydney.edu.au/medicine/radiation-physics/about-us/disclosures.php.

  13. WE-EF-BRD-00: New Developments in Hybrid MR-Treatment: Applications

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2015-06-15

    MRI-guided treatment is a growing area of medicine, particularly in radiotherapy and surgery. The exquisite soft tissue anatomic contrast offered by MRI, along with functional imaging, makes the use of MRI during therapeutic procedures very attractive. Challenging the utility of MRI in the therapy room are many issues including the physics of MRI and the impact on the environment and therapeutic instruments, the impact of the room and instruments on the MRI; safety, space, design and cost. In this session, the applications and challenges of MRI-guided treatment will be described. The session format is: Past, present and future: MRI-guided radiotherapy from 2005 to 2025: Jan Lagendijk Battling Maxwell’s equations: Physics challenges and solutions for hybrid MRI systems: Paul Keall I want it now!: Advances in MRI acquisition, reconstruction and the use of priors to enable fast anatomic and physiologic imaging to inform guidance and adaptation decisions: Yanle Hu MR in the OR: The growth and applications of MRI for interventional radiology and surgery: Rebecca Fahrig Learning Objectives: To understand the history and trajectory of MRI-guided radiotherapy To understand the challenges of integrating MR imaging systems with linear accelerators To understand the latest in fast MRI methods to enable the visualisation of anatomy and physiology on radiotherapy treatment timescales To understand the growing role and challenges of MRI for image-guided surgical procedures My disclosures are publicly available and updated at: http://sydney.edu.au/medicine/radiation-physics/about-us/disclosures.php.

  14. Volume rejuvenation of the facial upper third.

    Science.gov (United States)

    Buckingham, Edward D; Glasgold, Robert; Kontis, Theda; Smith, Stephen P; Dolev, Yalon; Fitzgerald, Rebecca; Lam, Samuel M; Williams, Edwin F; Pollei, Taylor R

    2015-02-01

    The next three articles in this issue take a unique approach to discussing volumetric restoration. Robert Glasgold has provided an assessment for each facial region and five different renowned authors (TK, SPS, RF, SML, and EFW) have been asked to speak on a particular volumetric product, of which they are considered an expert, as it applies to the different regions of the face. The articles are broken into the following: (1) upper third which corresponds to the upper eyelid, brow, temple, and forehead; (2) middle third which will cover lower eyelid, cheek, and perioral area; and (3) lower third which discusses the marionette, prejowl, and jawline. Our hope is that by placing differing opinions of experienced authors, organized by facial region together, the reader will have the opportunity to more readily compare the options. The contributing authors and their product area are as follows: Theda Kontis, MD-hyaluronic acid; Steve Smith, MD-calcium hydroxyl appetite; Rebecca Fitzgerald, MD-poly-L lactic acid; Sam Lam, MD-polymethyl methacrylate; and Edwin Williams, MD-Autologous Fat Transfer. If the author included general comments on the product, they are included in the article on the upper face only and are not repeated. Please note that other individuals may also have significantly assisted in the production of these articles, but those listed above are the senior authors. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  15. Lifestyle modification in the management of the metabolic syndrome: achievements and challenges

    Directory of Open Access Journals (Sweden)

    Marchesini G

    2010-11-01

    Full Text Available Riccardo Dalle Grave1, Simona Calugi1, Elena Centis2, Rebecca Marzocchi2, Marwan El Ghoch1, Giulio Marchesini21Department of Eating & Weight Disorder, Villa Garda Hospital, Garda (VR, Italy; 2Unit of Metabolic Diseases & Clinical Dietetics, Alma Mater Studiorum – University of Bologna, Bologna, ItalyAbstract: Lifestyle modification based on behavior therapy is the most important and effective strategy to manage the metabolic syndrome. Modern lifestyle modification therapy combines specific recommendations on diet and exercise with behavioral and cognitive strategies. The intervention may be delivered face-to-face or in groups, or in groups combined with individual sessions. The main challenge of treatment is helping patients maintain healthy behavior changes in the long term. In the last few years, several strategies have been evaluated to improve the long-term effect of lifestyle modification. Promising results have been achieved by combining lifestyle modification with pharmacotherapy, using meals replacement, setting higher physical activity goals, and long-term care. The key role of cognitive processes in the success/failure of weight loss and maintenance suggests that new cognitive procedures and strategies should be included in the traditional lifestyle modification interventions, in order to help patients build a mind-set favoring long-term lifestyle changes. These new strategies raise optimistic expectations for an effective treatment of metabolic syndrome with lifestyle modifications, provided public health programs to change the environment where patients live support them.Keywords: metabolic syndrome, obesity, lifestyle modification, cognitive behavior therapy

  16. Canine separation anxiety: strategies for treatment and management

    Directory of Open Access Journals (Sweden)

    Sargisson RJ

    2014-10-01

    Full Text Available Rebecca J Sargisson School of Psychology, University of Waikato, Tauranga, New ZealandAbstract: Dogs with separation-related behavior problems engage in unwanted behavior such as destruction of property and excessive vocalization when left alone, causing distress for both the dog and the owner, and often leading to the dog being relinquished or euthanized. I review research on factors likely to predispose dogs to developing separation anxiety and on the treatments available. Although research is equivocal, dogs seem to develop separation-related behavior problems if they are male, sourced from shelters or found, and separated from the litter before they are 60 days old. Protective factors include ensuring a wide range of experiences outside the home and with other people between the ages of 5–10 months, stable household routines and absences from the dog, and the avoidance of punishment. The most successful treatment for canine separation-related problems may be behavior modification that focuses on systematic desensitization and counterconditioning, which can be supplemented with medication in the initial stages. Where individual therapy from an animal behavior expert is not possible, advice to dog owners should be clear, simple, and contain five or fewer instructions to improve adherence. Advice is given for people seeking to adopt a dog, for new dog owners, and for existing dog owners who wish to treat their dog’s separation anxiety.Keywords: systematic desensitization, counterconditioning, medication, separation anxiety

  17. Life expectancy of the 20th century Venda: a compilation of skeletal and cemetery data.

    Science.gov (United States)

    L'Abbé, E N; Steyn, M; Loots, M

    2008-01-01

    Little information is available on the 20th century mortality rates of rural black South African groups, such as the Venda. The purpose of this study was to apply abridged life tables in order to estimate life expectancy from both skeletal remains and death registry information of modern South African communities. Comparisons were also made with prehistoric and contemporary groups as a means to better evaluate life expectancy for this time period. The sample consisted of 160 skeletons of known Venda origin and burial registry information for 1364 black South Africans from the Rebecca Street and Mamelodi Cemeteries in Pretoria, South Africa. Standard anthropological techniques were applied to determine sex and estimate age from the skeletal remains. The stationary and non-stationary life table models were used to analyse the data. A high rate of child mortality, low juvenile and adult mortality with a steady increase in mortality after the age of 30 years was observed for both the Venda and the cemetery samples. Throughout the 20th century, life expectancy was shown to increase for black South Africans. However, due to the widespread HIV infection/AIDS of the 21st century, infant and young adult mortality rates continue to rise at such a speed that the decline in mortality seen for South Africans in the last 50 years will most likely to be lost in the next decade due to this disease.

  18. WE-EF-BRD-02: Battling Maxwell’s Equations: Physics Challenges and Solutions for Hybrid MRI Systems

    International Nuclear Information System (INIS)

    Keall, P.

    2015-01-01

    MRI-guided treatment is a growing area of medicine, particularly in radiotherapy and surgery. The exquisite soft tissue anatomic contrast offered by MRI, along with functional imaging, makes the use of MRI during therapeutic procedures very attractive. Challenging the utility of MRI in the therapy room are many issues including the physics of MRI and the impact on the environment and therapeutic instruments, the impact of the room and instruments on the MRI; safety, space, design and cost. In this session, the applications and challenges of MRI-guided treatment will be described. The session format is: Past, present and future: MRI-guided radiotherapy from 2005 to 2025: Jan Lagendijk Battling Maxwell’s equations: Physics challenges and solutions for hybrid MRI systems: Paul Keall I want it now!: Advances in MRI acquisition, reconstruction and the use of priors to enable fast anatomic and physiologic imaging to inform guidance and adaptation decisions: Yanle Hu MR in the OR: The growth and applications of MRI for interventional radiology and surgery: Rebecca Fahrig Learning Objectives: To understand the history and trajectory of MRI-guided radiotherapy To understand the challenges of integrating MR imaging systems with linear accelerators To understand the latest in fast MRI methods to enable the visualisation of anatomy and physiology on radiotherapy treatment timescales To understand the growing role and challenges of MRI for image-guided surgical procedures My disclosures are publicly available and updated at: http://sydney.edu.au/medicine/radiation-physics/about-us/disclosures.php

  19. WE-EF-BRD-00: New Developments in Hybrid MR-Treatment: Applications

    International Nuclear Information System (INIS)

    2015-01-01

    MRI-guided treatment is a growing area of medicine, particularly in radiotherapy and surgery. The exquisite soft tissue anatomic contrast offered by MRI, along with functional imaging, makes the use of MRI during therapeutic procedures very attractive. Challenging the utility of MRI in the therapy room are many issues including the physics of MRI and the impact on the environment and therapeutic instruments, the impact of the room and instruments on the MRI; safety, space, design and cost. In this session, the applications and challenges of MRI-guided treatment will be described. The session format is: Past, present and future: MRI-guided radiotherapy from 2005 to 2025: Jan Lagendijk Battling Maxwell’s equations: Physics challenges and solutions for hybrid MRI systems: Paul Keall I want it now!: Advances in MRI acquisition, reconstruction and the use of priors to enable fast anatomic and physiologic imaging to inform guidance and adaptation decisions: Yanle Hu MR in the OR: The growth and applications of MRI for interventional radiology and surgery: Rebecca Fahrig Learning Objectives: To understand the history and trajectory of MRI-guided radiotherapy To understand the challenges of integrating MR imaging systems with linear accelerators To understand the latest in fast MRI methods to enable the visualisation of anatomy and physiology on radiotherapy treatment timescales To understand the growing role and challenges of MRI for image-guided surgical procedures My disclosures are publicly available and updated at: http://sydney.edu.au/medicine/radiation-physics/about-us/disclosures.php

  20. 2012 best practices for repositories collection, storage, retrieval, and distribution of biological materials for research international society for biological and environmental repositories.

    Science.gov (United States)

    2012-04-01

    Third Edition [Formula: see text] [Box: see text] Printed with permission from the International Society for Biological and Environmental Repositories (ISBER) © 2011 ISBER All Rights Reserved Editor-in-Chief Lori D. Campbell, PhD Associate Editors Fay Betsou, PhD Debra Leiolani Garcia, MPA Judith G. Giri, PhD Karen E. Pitt, PhD Rebecca S. Pugh, MS Katherine C. Sexton, MBA Amy P.N. Skubitz, PhD Stella B. Somiari, PhD Individual Contributors to the Third Edition Jonas Astrin, Susan Baker, Thomas J. Barr, Erica Benson, Mark Cada, Lori Campbell, Antonio Hugo Jose Froes Marques Campos, David Carpentieri, Omoshile Clement, Domenico Coppola, Yvonne De Souza, Paul Fearn, Kelly Feil, Debra Garcia, Judith Giri, William E. Grizzle, Kathleen Groover, Keith Harding, Edward Kaercher, Joseph Kessler, Sarah Loud, Hannah Maynor, Kevin McCluskey, Kevin Meagher, Cheryl Michels, Lisa Miranda, Judy Muller-Cohn, Rolf Muller, James O'Sullivan, Karen Pitt, Rebecca Pugh, Rivka Ravid, Katherine Sexton, Ricardo Luis A. Silva, Frank Simione, Amy Skubitz, Stella Somiari, Frans van der Horst, Gavin Welch, Andy Zaayenga 2012 Best Practices for Repositories: Collection, Storage, Retrieval and Distribution of Biological Materials for Research INTERNATIONAL SOCIETY FOR BIOLOGICAL AND ENVIRONMENTAL REPOSITORIES (ISBER) INTRODUCTION T he availability of high quality biological and environmental specimens for research purposes requires the development of standardized methods for collection, long-term storage, retrieval and distribution of specimens that will enable their future use. Sharing successful strategies for accomplishing this goal is one of the driving forces for the International Society for Biological and Environmental Repositories (ISBER). For more information about ISBER see www.isber.org . ISBER's Best Practices for Repositories (Best Practices) reflect the collective experience of its members and has received broad input from other repository professionals. Throughout this document

  1. Consentimento dos conectados: a luta mundial pela internet livre

    Directory of Open Access Journals (Sweden)

    Elaine Cristina Xiol y Ferreira

    2013-05-01

    Full Text Available Resenha: A presente obra não se trata de um mero apanhado dos recentes movimentos de protestos e revoluções sociais que se utilizaram da internet como instrumentário para busca da democracia, mas, sim, é o resultado de uma vasta pesquisa sobre a evolução da internet e suas políticas de uso atualmente existentes em todo o mundo. Rebecca Mackinnon, conhecida jornalista e ativista do movimento da internet livre , faz um alerta sobre o tema. Seu intuito é atrair a atenção dos leitores para o verdadeiro papel e poder das tecnologias da internet e das redes digitais. O cerne da discussão envolve o fato de as grandes corporações e os governos que constroem, operam e supervisionam o espaço cibernético, ainda não serem suficientemente responsabilizados pelos abusos perpetrados contra a vida e a identidade das pessoas que se utilizam das redes digitais. A obra também examina algumas questões polêmicas das políticas de uso presentes em inúmeros debates nacionais e internacionais como a privacidade online, a regulação da neutralidade da rede, questões de liberdade de expressão e de direitos autorais. Aparentemente vivenciamos um “novo contrato social, no qual os indivíduos dão ao Estado o poder sobre a informação em troca de segurança e da conveniência de se viver no mundo moderno”.

  2. Savannah River Ecology Laboratory. Annual technical progress report of ecological research

    International Nuclear Information System (INIS)

    Smith, M.H.

    1996-01-01

    The Savannah River Ecology Laboratory (SREL) is a research unit of the University of Georgia (UGA). The overall mission of the Laboratory is to acquire and communicate knowledge of ecological processes and principles. SREL conducts basic and applied ecological research, as well as education and outreach programs, under a contract with the U.S. Department of Energy (DOE) at the Savannah River Site (SRS) near Aiken, South Carolina. Significant accomplishments were made during the past year in the areas of research, education and service. The Laboratory's research mission was fulfilled with the publication of two books and 143 journal articles and book chapters by faculty, technical and students, and visiting scientists. An additional three books and about 80 journal articles currently are in press. Faculty, technician and students presented 193 lectures, scientific presentations, and posters to colleges and universities, including minority institutions. Dr. J Vaun McArthur organized and conducted the Third Annual SREL Symposium on the Environment: New Concepts in Strewn Ecology: An Integrative Approach. Dr. Michael Newman conducted a 5-day course titled Quantitative Methods in Ecotoxicology, and Dr. Brian Teppen of The Advanced Analytical Center for Environmental Sciences (AACES) taught a 3-day short course titled Introduction to Molecular Modeling of Environmental Systems. Dr. I. Lehr Brisbin co-hosted a meeting of the Crocodile Special Interest Group. Dr. Rebecca Sharitz attended four symposia in Japan during May and June 1996 and conducted meetings of the Executive Committee and Board of the International Association for Ecology (ENTECOL)

  3. Nelfinavir is effective against human cervical cancer cells in vivo: a potential treatment modality in resource-limited settings

    Directory of Open Access Journals (Sweden)

    Davis MA

    2016-06-01

    Full Text Available Mitzie-Ann Davis,* Joe R Delaney,* Chandni B Patel, Ryan Storgard, Dwayne G Stupack Division of Gynecologic Oncology, Department of Reproductive Medicine, Rebecca and John UCSD Moores Cancer Center, La Jolla, CA, USA *These authors contributed equally to this work Objective: The standard treatment for cervical cancer in developed countries includes surgery and chemoradiation, with standard of care lagging in developing countries. Even in the former case, treatment frequently yields recalcitrant tumors and women succumb to disease. Here we examine the impact of nelfinavir, an off-patent viral protease inhibitor, which has shown promise as an antineoplastic agent. Methods: We evaluated the morphological and proliferative effects of the autophagy-stressing drug nelfinavir in normal and cisplatin-resistant cervical cancer cells. Immunofluorescent validation of autophagy markers was performed and the impact of nelfinavir in an in vivo model of tumor growth was determined. Results: Nelfinavir exhibits cytotoxicity against both cisplatin-sensitive and -resistant ME-180 human cervical cancer cells in vitro and in vivo. Immunoblotting and immunofluorescence showed an expression of the autophagy marker LC3-II in response to nelfinavir treatment. Conclusion: Nelfinavir, now available as an inexpensive generic orally dosed agent (Nelvir, is cytotoxic against cervical cancer cells. It acts by burdening the autophagy pathway to impair tumor cell survival and a modest induction of apoptosis. While further studies are needed to elucidate the optimal method of application of nelfinavir, it may represent an appealing global option for the treatment of cervical cancer. Keywords: cervical cancer, nelfinavir, cisplatin resistance, autophagy, responsible medicine

  4. PREFACE: Soil Change Matters 2014

    Science.gov (United States)

    2015-07-01

    The opinions expressed and arguments employed in this publication are the sole responsibility of the authors and do not necessarily reflect those of the OECD or of the governments of its Member countries. The Workshop was sponsored by the OECD Co-operative Research Programme on Biological Resource Management for Sustainable Agricultural Systems, whose financial support made it possible for eight of the invited speakers to participate in the Workshop. We would like to thank the Organising Committee, the Scientific Committee and the financial support from the conference sponsors and funding from the Government of Victoria that allowed the success of the Soil Change Matters Workshop. Organising Committee (Department of Economic Development, Jobs, Transport and Resources unless otherwise noted): • Richard MacEwan (Convenor) • Jennifer Alexander • Helaina Black (James Hutton Institute, UK) • Doug Crawford • Phil Dyson (North Central CMA) • Jane Fisher • Gemma Heemskerk • Jonathan Hopley • Pauline Mele • Rebecca Mitchell • David Rees • Dugal Wallace • Dale Webster Scientific Committee (Department of Economic Development, Jobs, Transport and Resources unless otherwise noted): • Mr Richard MacEwan • Dr Dominique Arrouays (National Institute of Agronomic Research, France) • Helaina Black (James Hutton Institute, UK) • Mr Doug Crawford • Dr Ben Marchant (Geoscience, UK) • Dr Pauline Mele • Dr Budiman Minasny (University of Sydney, NSW) • Professor Dan Richter (Duke University, USA) • Mr Nathan Robinson Thanks are given to the authors and to the anonymous referees for the papers included here.

  5. Savannah River Ecology Laboratory. Annual technical progress report of ecological research

    Energy Technology Data Exchange (ETDEWEB)

    Smith, M.H.

    1996-07-31

    The Savannah River Ecology Laboratory (SREL) is a research unit of the University of Georgia (UGA). The overall mission of the Laboratory is to acquire and communicate knowledge of ecological processes and principles. SREL conducts basic and applied ecological research, as well as education and outreach programs, under a contract with the U.S. Department of Energy (DOE) at the Savannah River Site (SRS) near Aiken, South Carolina. Significant accomplishments were made during the past year in the areas of research, education and service. The Laboratory`s research mission was fulfilled with the publication of two books and 143 journal articles and book chapters by faculty, technical and students, and visiting scientists. An additional three books and about 80 journal articles currently are in press. Faculty, technician and students presented 193 lectures, scientific presentations, and posters to colleges and universities, including minority institutions. Dr. J Vaun McArthur organized and conducted the Third Annual SREL Symposium on the Environment: New Concepts in Strewn Ecology: An Integrative Approach. Dr. Michael Newman conducted a 5-day course titled Quantitative Methods in Ecotoxicology, and Dr. Brian Teppen of The Advanced Analytical Center for Environmental Sciences (AACES) taught a 3-day short course titled Introduction to Molecular Modeling of Environmental Systems. Dr. I. Lehr Brisbin co-hosted a meeting of the Crocodile Special Interest Group. Dr. Rebecca Sharitz attended four symposia in Japan during May and June 1996 and conducted meetings of the Executive Committee and Board of the International Association for Ecology (ENTECOL).

  6. A Brief Introduction on Peer Review: New Possibilities

    Directory of Open Access Journals (Sweden)

    Sean Scanlan

    2013-06-01

    Full Text Available From the classroom, to the lab, to the studio, to industry, and to the academy, evaluating work is part of everyday life. Whether we call it critiquing, refereeing, or peer reviewing, the goals are the same: to make the object under review better, to verify that its claims are not false, or at the very least, to ascertain that the object has some merit. Jenna Pack Sheffield’s note "Open Peer Review: Collective Intelligence as a Framework for Theorizing Approaches to Peer Review in the Humanities" discusses the definition of “open peer review” and looks at various ways it’s been used to highlight the advantages and disadvantages of the process. This issue of NANO includes interviews with three editors who share their ideas about the shape of current peer review problems and what the future might look like for academics, tenure review boards, and publishers. First, Sean Scanlan conducted an email interview with Masoud Yazdani, the editor of Intellect Books, an independent academic publisher in the fields of creative practice and popular culture, whose aim is to publish scholarly books and journals that provide a vital space for widening critical debate in new and emerging subjects. Second, Sean Scanlan interviews Aaron Barlow, of New York City College of Technology, who shares his views on the problems of traditional peer review. Third, NANO assistant editor Rebecca Devers interviews Martha J. Cutter, the former editor of MELUS, about the complexities of processing, reviewing, and publishing a journal that receives in over 300 submissions each year.

  7. Employee performance in the knowledge economy: Capturing the keys to success

    Directory of Open Access Journals (Sweden)

    Rebecca Fauth

    2008-11-01

    Full Text Available Rebecca Fauth1, Stephen Bevan1, Peter Mills2,31The Work Foundation, London, UK; 2CIGNA, London, UK; 3The Whittington Hospital, London, UKAbstract: The present study examines the key determinants of employee performance in a knowledge-intensive service firm located in the UK. Using data from a pilot study, we mapped eight performance-related behaviors to two measures of global performance to isolate the strongest predictors of the latter. We also examined the degree to which these associations varied depending on whether employees or their managers reported on performance as well as according to the degree of complexity (eg, ongoing learning, multitasking, problem solving, etc. present in workers’ jobs. Findings revealed that more traditional employee performance-related behaviors (eg, dependability as well as behaviors that have likely increased in importance in the knowledge economy (eg, sharing ideas and information accounted for the most variance in reported global performance. Sharing ideas and information was a particularly important predictor for workers in complex jobs. When the performance-related behaviors were regressed on the organization’s annual employee appraisal ratings, only dependability and time management behaviors were significantly associated with the outcome. As organizational success increasingly is dependent on intangible inputs stemming from the ideas, innovations and creativity of its workforce, organizations need to ensure that they are capturing the full range of behaviors that help to define their success. Further research with a diverse range of organizations will help defi ne this further.Keywords: employee performance, knowledge economy, job complexity

  8. Using HeLa cell stress response to introduce first year students to the scientific method, laboratory techniques, primary literature, and scientific writing.

    Science.gov (United States)

    Resendes, Karen K

    2015-01-01

    Incorporating scientific literacy into inquiry driven research is one of the most effective mechanisms for developing an undergraduate student's strength in writing. Additionally, discovery-based laboratories help develop students who approach science as critical thinkers. Thus, a three-week laboratory module for an introductory cell and molecular biology course that couples inquiry-based experimental design with extensive scientific writing was designed at Westminster College to expose first year students to these concepts early in their undergraduate career. In the module students used scientific literature to design and then implement an experiment on the effect of cellular stress on protein expression in HeLa cells. In parallel the students developed a research paper in the style of the undergraduate journal BIOS to report their results. HeLa cells were used to integrate the research experience with the Westminster College "Next Chapter" first year program, in which the students explored the historical relevance of HeLa cells from a sociological perspective through reading The Immortal Life of Henrietta Lacks by Rebecca Skloot. In this report I detail the design, delivery, student learning outcomes, and assessment of this module, and while this exercise was designed for an introductory course at a small primarily undergraduate institution, suggestions for modifications at larger universities or for upper division courses are included. Finally, based on student outcomes suggestions are provided for improving the module to enhance the link between teaching students skills in experimental design and execution with developing student skills in information literacy and writing. © 2015 The International Union of Biochemistry and Molecular Biology.

  9. Discovery of dominant and dormant genes from expression data using a novel generalization of SNR for multi-class problems

    Directory of Open Access Journals (Sweden)

    Chung I-Fang

    2008-10-01

    Full Text Available Abstract Background The Signal-to-Noise-Ratio (SNR is often used for identification of biomarkers for two-class problems and no formal and useful generalization of SNR is available for multiclass problems. We propose innovative generalizations of SNR for multiclass cancer discrimination through introduction of two indices, Gene Dominant Index and Gene Dormant Index (GDIs. These two indices lead to the concepts of dominant and dormant genes with biological significance. We use these indices to develop methodologies for discovery of dominant and dormant biomarkers with interesting biological significance. The dominancy and dormancy of the identified biomarkers and their excellent discriminating power are also demonstrated pictorially using the scatterplot of individual gene and 2-D Sammon's projection of the selected set of genes. Using information from the literature we have shown that the GDI based method can identify dominant and dormant genes that play significant roles in cancer biology. These biomarkers are also used to design diagnostic prediction systems. Results and discussion To evaluate the effectiveness of the GDIs, we have used four multiclass cancer data sets (Small Round Blue Cell Tumors, Leukemia, Central Nervous System Tumors, and Lung Cancer. For each data set we demonstrate that the new indices can find biologically meaningful genes that can act as biomarkers. We then use six machine learning tools, Nearest Neighbor Classifier (NNC, Nearest Mean Classifier (NMC, Support Vector Machine (SVM classifier with linear kernel, and SVM classifier with Gaussian kernel, where both SVMs are used in conjunction with one-vs-all (OVA and one-vs-one (OVO strategies. We found GDIs to be very effective in identifying biomarkers with strong class specific signatures. With all six tools and for all data sets we could achieve better or comparable prediction accuracies usually with fewer marker genes than results reported in the literature using the

  10. Biologics in the management of ulcerative colitis – comparative safety and efficacy of TNF-α antagonists

    Directory of Open Access Journals (Sweden)

    Fausel R

    2015-01-01

    Full Text Available Rebecca Fausel,1 Anita Afzali1,2 1Division of Gastroenterology, Department of Medicine, University of Washington, Seattle, WA, USA; 2Inflammatory Bowel Disease Program, UW Medicine – Harborview Medical Center, Seattle, WA, USA Abstract: Ulcerative colitis can cause debilitating symptoms and complications such as colonic strictures, colonic dysplasia, colorectal cancer, and toxic megacolon or perforation. Goals of treatment in ulcerative colitis include resolution of gastrointestinal symptoms, healing of colonic mucosa, and prevention of disease complications. Our treatment armamentarium has expanded dramatically over the past 10 years, and we now have multiple biologic agents approved for the treatment of moderate-severe disease, in addition to conventional therapies such as 5-aminosalicylates, thiopurines, and corticosteroids. In this review, we will provide a detailed discussion of the three tumor necrosis factor-alpha (TNF-α inhibitors currently approved for treatment of ulcerative colitis: infliximab, adalimumab, and golimumab. All three agents are effective for inducing and maintaining clinical response and remission in patients with ulcerative colitis, and they have comparable safety profiles. There are no head-to-head trials comparing their efficacy, and the choice of agent is most often based on insurance coverage, route of administration, and patient preference. Combination therapy with an immunomodulator is proven to be more effective than anti-TNF monotherapy, and patients who lose response to an anti-TNF agent should undergo dose intensification in order to regain clinical response. Despite therapeutic optimization, a significant percentage of patients will not achieve clinical remission with anti-TNF agents, and so newer therapies are on the horizon. Keywords: ulcerative colitis, inflammatory bowel disease, infliximab, adalimumab, golimumab

  11. Pilot study on the additive effects of berberine and oral type 2 diabetes agents for patients with suboptimal glycemic control

    Directory of Open Access Journals (Sweden)

    Di Pierro F

    2012-07-01

    Full Text Available Francesco Di Pierro,1 Nicola Villanova,2 Federica Agostini,2 Rebecca Marzocchi,2 Valentina Soverini,2 Giulio Marchesini21Scientific Department, Velleja Research, Milano, 2Diseases of Metabolism, S Orsola Malpighi Hospital, Bologna, ItalyBackground: Suboptimal glycemic control is a common situation in diabetes, regardless of the wide range of drugs available to reach glycemic targets. Basic research in diabetes is endeavoring to identify new actives working as insulin savers, use of which could delay the introduction of injectable insulin or reduce the insulin dose needed. Commonly available as a nutraceutical, berberine is a potential candidate.Methods and results: Because its low oral bioavailability can be overcome by P-glycoprotein inhibitors like herbal polyphenols, we have tested the nutraceutical combination of Berberis aristata extract and Silybum marianum extract (Berberol® in type 2 diabetes in terms of its additive effect when combined with a conventional oral regimen for patients with suboptimal glycemic control. After 90 days of treatment, the nutraceutical association had a positive effect on glycemic and lipid parameters, significantly reducing glycosylated hemoglobin, basal insulin, homeostatic model assessment of insulin resistance, total and low-density lipoprotein cholesterol, and triglycerides. A relevant effect was also observed in terms of liver function by measuring aspartate transaminase and alanine transaminase. The product had a good safety profile, with distinctive gastrointestinal side effects likely due to its acarbose-like action.Conclusion: Although further studies should be carried out to confirm our data, Berberol could be considered a good candidate as an adjunctive treatment option in diabetes, especially in patients with suboptimal glycemic control.Keywords: berberine, silymarin, glycosylated hemoglobin, diabetes

  12. Telehealth and eHealth in nurse practitioner training: current perspectives

    Directory of Open Access Journals (Sweden)

    Rutledge CM

    2017-06-01

    Full Text Available Carolyn M Rutledge,1 Karen Kott,2 Patty A Schweickert,3 Rebecca Poston,1 Christianne Fowler,1 Tina S Haney1 1College of Health Sciences, School of Nursing, 2College of Health Sciences, School of Physical Therapy, Old Dominion University, Norfolk, 3Department of Neuroradiology, University of Virginia, Charlottesville, VA, USA Abstract: Telehealth is becoming a vital process for providing access to cost-effective quality care to patients at a distance. As such, it is important for nurse practitioners, often the primary providers for rural and disadvantaged populations, to develop the knowledge, skills, and attitudes needed to utilize telehealth technologies in practice. In reviewing the literature, very little information was found on programs that addressed nurse practitioner training in telehealth. This article provides an overview of both the topics and the techniques that have been utilized for training nurse practitioners and nurse practitioner students in the delivery of care utilizing telehealth. Specifically, this article focuses on topics including 1 defining telehealth, 2 telehealth etiquette, 3 interprofessional collaboration, 4 regulations, 5 reimbursement, 6 security/Health Insurance Portability and Accountability Act (HIPAA, 7 ethical practice in telehealth, and 8 satisfaction of patients and providers. A multimodal approach based on a review of the literature is presented for providing the training: 1 didactics, 2 simulations including standardized patient encounters, 3 practice immersions, and 4 telehealth projects. Studies found that training using the multimodal approach allowed the students to develop comfort, knowledge, and skills needed to embrace the utilization of telehealth in health care. Keywords: telehealth, nurse practitioner education, telemedicine, simulation, health care

  13. Health Information Technology Usability Evaluation Scale (Health-ITUES) for Usability Assessment of Mobile Health Technology: Validation Study.

    Science.gov (United States)

    Schnall, Rebecca; Cho, Hwayoung; Liu, Jianfang

    2018-01-05

    Mobile technology has become a ubiquitous technology and can be particularly useful in the delivery of health interventions. This technology can allow us to deliver interventions to scale, cover broad geographic areas, and deliver technologies in highly tailored ways based on the preferences or characteristics of users. The broad use of mobile technologies supports the need for usability assessments of these tools. Although there have been a number of usability assessment instruments developed, none have been validated for use with mobile technologies. The goal of this work was to validate the Health Information Technology Usability Evaluation Scale (Health-ITUES), a customizable usability assessment instrument in a sample of community-dwelling adults who were testing the use of a new mobile health (mHealth) technology. A sample of 92 community-dwelling adults living with HIV used a new mobile app for symptom self-management and completed the Health-ITUES to assess the usability of the app. They also completed the Post-Study System Usability Questionnaire (PSSUQ), a widely used and well-validated usability assessment tool. Correlations between these scales and each of the subscales were assessed. The subscales of the Health-ITUES showed high internal consistency reliability (Cronbach alpha=.85-.92). Each of the Health-ITUES subscales and the overall scale was moderately to strongly correlated with the PSSUQ scales (r=.46-.70), demonstrating the criterion validity of the Health-ITUES. The Health-ITUES has demonstrated reliability and validity for use in assessing the usability of mHealth technologies in community-dwelling adults living with a chronic illness. ©Rebecca Schnall, Hwayoung Cho, Jianfang Liu. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 05.01.2018.

  14. Factors associated with severe preeclampsia and eclampsia in Jahun, Nigeria

    Directory of Open Access Journals (Sweden)

    Guerrier G

    2013-08-01

    Full Text Available Gilles Guerrier,1 Bukola Oluyide,2 Maria Keramarou,1 Rebecca Grais11Epicentre, Paris, France; 2Médecins Sans Frontières, Paris, FranceObjective: To explore traditional herbal medicines as potential risk factors of severe preeclampsia and eclampsia in Nigeria.Methods: We conducted a retrospective case-control study from October 2010 to May 2011. The cases were all pregnant women admitted to the Jahun Hospital during the study period with severe preeclampsia or eclampsia and women presenting with normal pregnancy after 22 weeks.Results: During the study period, a total of 1,257 women (44% were recorded as having normal pregnancy, and 419 (16% women had severe preeclampsia/eclampsia (175 with severe preeclampsia and 244 with eclampsia. The risk factors found to be associated with a greater risk of severe preeclampsia/eclampsia included personal history of preeclampsia (odds ratio [OR] = 21.5; P < 0.001, personal history of preexisting hypertension (OR = 10.5; P < 0.001, primiparity (OR = 2.5; P = 0.001, occupation as housewife (OR = 1.9; P = 0.008, and fewer than four antenatal care visits (OR = 1.6; P = 0.02. Use of traditional treatments during pregnancy was associated with a higher risk of developing severe preeclampsia/eclampsia (OR = 1.6 95%; confidence interval [CI]: 1.2-2.1 by univariate analysis only.Conclusion: Use of traditional treatment, which increases delays before consulting the official health sector, might be a marker for harmful behavior. Community-based studies could provide additional information on the practice of herbal therapy in this population.Keywords: hypertensive disorders, pregnancy, traditional treatments, herbal use

  15. Evaluation of patients’ experiences at different stages of the intravitreal injection procedure – what can be improved?

    Directory of Open Access Journals (Sweden)

    Tailor R

    2011-10-01

    Full Text Available Rajen Tailor, Rebecca Beasley, Yit Yang, Niro NarendranWolverhampton and Midland Counties Eye Infirmary, New Cross Hospital, Wolverhampton, UKIntroduction: Intravitreal injection of ranibizumab has become one of the most commonly performed ophthalmic procedures. It is timely to conduct an evaluation of the injection procedure from the patient’s perspective so as to determine ways to improve patient experience. The purpose of this study was to quantitatively describe patients’ experiences of the different stages of the intravitreal injection procedure and provide suggestions for improvement.Method: Following intravitreal injection, patients were administered a questionnaire to score the distress felt for each of ten parts of the whole injection process from the initial waiting to the final instillation of topical antibiotic at the end. A score of higher than 4 was regarded as significantly unpleasant. The proportion of scores above 4 for each step was used to evaluate the relative distress experienced by patients for the different parts of the procedure.Results: A total of 42 patients were surveyed. The step with the highest percentage of patients scoring more than 4 was the injection step (19%. However, cumulatively, the steps relating to the application of the drape, the speculum, and the removal of drape accounted for 53% of scores greater than 4.Conclusion: There is considerable variation in how patients tolerate different stages of the injection procedure. The needle entry was the most unpleasant step followed by the draping steps cumulatively. Use of subconjunctival anesthesia, a perforated drape, and alternative lid exclusion devices may help to improve the patient’s tolerability of the procedure and experience.Keywords: ranibizumab, patient experience, age-related macular degeneration

  16. Temperature dependence of carbon kinetic isotope effect for the oxidation reaction of ethane by OH radicals under atmospherically relevant conditions

    Science.gov (United States)

    Piansawan, Tammarat; Saccon, Marina; Laumer, Werner; Gensch, Iulia; Kiendler-Scharr, Astrid

    2015-04-01

    Modeling of the global distribution of atmospheric ethane sources and sinks by using the 13C isotopic composition requires accurate knowledge of the carbon kinetic isotope effect (KIE) of its atmospheric removal reactions. The quantum mechanical prediction implies the necessity to elucidate the temperature dependence of KIE within atmospherically relevant temperature range by experiment. In this study, the KIE and its temperature dependence for ethane oxidation by OH radicals was investigated at ambient pressure in a temperature range of 243 K to 303 K. The chemical reactions were carried out in a 15 L PFE reaction chamber, suspended in a thermally controlled oven. The isotope ratios of the gas phase components during the course of the reactions were measured by Thermal Desorption -- Gas Chromatography -- Isotope Ratio Mass Spectrometry (TD-GC-IRMS). For each temperature, the KIE was derived from the temporal evolution of the concentration and stable carbon isotope ratio (δ13C) of ethane using a method adapted from the relative reaction rate concept. The room temperature KIE of the ethane reaction with OH radicals was found to be 6.85 ± 0.32 ‰. This value is in agreement with the previously reported value of 8.57 ± 1.95 ‰ [Anderson et al. 2004] but has a substantially lower uncertainty. The experimental results will be discussed with the KIE temperature dependence predicted by quantum mechanical calculations. Reference: Rebecca S. Anderson, Lin Huang, Richard Iannone, Alexandra E. Thompson, and Jochen Rudolph (2004), Carbon Kinetic Isotope Effects in the Gas Phase Reactions of Light Alkanes and Ethene with the OH Radical at 296 ± 4 K, J. Phys. Chem. A, 108, 11537--11544

  17. Lormetazepam addiction: data analysis from an Italian medical unit for addiction

    Directory of Open Access Journals (Sweden)

    Faccini M

    2012-06-01

    Full Text Available Marco Faccini,1 Roberto Leone,2 Benedetta Pajusco,1 Gianluca Quaglio,1 Rebecca Casari,1 Anna Albiero,1 Monia Donati,2 Fabio Lugoboni11Department of Internal Medicine, Addiction Unit, 2Pharmacology Unit, Reference Center for Education and Communication within the World Health Organization Program for International Drug Monitoring, University Hospital of Verona, Verona, ItalyBackground: The purpose of this study was to determine, in the context of a hospital addiction unit, which benzodiazepines were abused and to look for correlations with the characteristics of detoxified patients.Methods: A retrospective study was carried out using the database of hospital admissions to the addiction unit for detoxification from 2003 to 2010.Results: Of 879 admissions to the addiction unit during the seven-year period, 281 were for benzodiazepines. The percentage of patients addicted only to benzodiazepines was higher among females than males. Benzodiazepine consumption had started as a drug addiction behavior in only 10% of cases. The main sources of prescription identified were general practitioners (52% of cases or compliant pharmacists (25%. Overall, 15 different benzodiazepines were abused, with lormetazepam being the most commonly used (by 123 patients, 43.8% of the total.Conclusion: Our data show that, outside the population of multidrug addicts, there is an underestimated group of chronic benzodiazepine consumers who are often not referred to medical institutions for treatment. Even in the group of patients addicted to one substance only, we observed an abnormal number of requests for detoxification from lormetazepam, which appears to be more "popular" than other benzodiazepines. This drug should be prescribed according to stricter criteria and submitted to closer control.Keywords: lormetazepam, benzodiazepines, addiction, inpatient detoxification

  18. Evolutionary thinking

    Science.gov (United States)

    Hunt, Tam

    2014-01-01

    Evolution as an idea has a lengthy history, even though the idea of evolution is generally associated with Darwin today. Rebecca Stott provides an engaging and thoughtful overview of this history of evolutionary thinking in her 2013 book, Darwin's Ghosts: The Secret History of Evolution. Since Darwin, the debate over evolution—both how it takes place and, in a long war of words with religiously-oriented thinkers, whether it takes place—has been sustained and heated. A growing share of this debate is now devoted to examining how evolutionary thinking affects areas outside of biology. How do our lives change when we recognize that all is in flux? What can we learn about life more generally if we study change instead of stasis? Carter Phipps’ book, Evolutionaries: Unlocking the Spiritual and Cultural Potential of Science's Greatest Idea, delves deep into this relatively new development. Phipps generally takes as a given the validity of the Modern Synthesis of evolutionary biology. His story takes us into, as the subtitle suggests, the spiritual and cultural implications of evolutionary thinking. Can religion and evolution be reconciled? Can evolutionary thinking lead to a new type of spirituality? Is our culture already being changed in ways that we don't realize by evolutionary thinking? These are all important questions and Phipps book is a great introduction to this discussion. Phipps is an author, journalist, and contributor to the emerging “integral” or “evolutionary” cultural movement that combines the insights of Integral Philosophy, evolutionary science, developmental psychology, and the social sciences. He has served as the Executive Editor of EnlightenNext magazine (no longer published) and more recently is the co-founder of the Institute for Cultural Evolution, a public policy think tank addressing the cultural roots of America's political challenges. What follows is an email interview with Phipps. PMID:26478766

  19. Individualization of antiretroviral therapy

    Directory of Open Access Journals (Sweden)

    Pavlos R

    2011-12-01

    Full Text Available Rebecca Pavlos, Elizabeth J PhillipsInstitute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia, AustraliaAbstract: Antiretroviral therapy (ART has evolved considerably over the last three decades. From the early days of monotherapy with high toxicities and pill burdens, through to larger pill burdens and more potent combination therapies, and finally, from 2005 and beyond where we now have the choice of low pill burdens and once-daily therapies. More convenient and less toxic regimens are also becoming available, even in resource-poor settings. An understanding of the individual variation in response to ART, both efficacy and toxicity, has evolved over this time. The strong association of the major histocompatibility class I allele HLA-B*5701 and abacavir hypersensitivity, and its translation and use in routine HIV clinical practice as a predictive marker with 100% negative predictive value, has been a success story and a notable example of the challenges and triumphs in bringing pharmacogenetics to the clinic. In real clinical practice, however, it is going to be the exception rather than the rule that individual biomarkers will definitively guide patient therapy. The need for individualized approaches to ART has been further increased by the importance of non-AIDS comorbidities in HIV clinical practice. In the future, the ideal utilization of the individualized approach to ART will likely consist of a combined approach using a combination of knowledge of drug, virus, and host (pharmacogenetic and pharmacoecologic [factors in the individual's environment that may be dynamic over time] information to guide the truly personalized prescription. This review will focus on our knowledge of the pharmacogenetics of the efficacy and toxicity of currently available antiretroviral agents and the current and potential utility of such information and approaches in present and future HIV clinical care.Keywords: HIV

  20. The eXtraordinarY Kids Clinic: an interdisciplinary model of care for children and adolescents with sex chromosome aneuploidy

    Directory of Open Access Journals (Sweden)

    Tartaglia N

    2015-07-01

    Full Text Available Nicole Tartaglia,1,2 Susan Howell,1,2 Rebecca Wilson,2 Jennifer Janusz,1,2 Richard Boada,1,2 Sydney Martin,2 Jacqueline B Frazier,2 Michelle Pfeiffer,2 Karen Regan,2 Sarah McSwegin,2 Philip Zeitler1,2 1Department of Pediatrics, University of Colorado School of Medicine, 2Child Development Unit, Children's Hospital Colorado, Aurora, CO, USA Purpose: Individuals with sex chromosome aneuploidies (SCAs are born with an atypical number of X and/or Y chromosomes, and present with a range of medical, developmental, educational, behavioral, and psychological concerns. Rates of SCA diagnoses in infants and children are increasing, and there is a need for specialized interdisciplinary care to address associated risks. The eXtraordinarY Kids Clinic was established to provide comprehensive and experienced care for children and adolescents with SCA, with an interdisciplinary team composed of developmental–behavioral pediatrics, endocrinology, genetic counseling, child psychology, pediatric neuropsychology, speech–language pathology, occupational therapy, nursing, and social work. The clinic model includes an interdisciplinary approach to care, where assessment results by each discipline are integrated to develop unified diagnostic impressions and treatment plans individualized for each patient. Additional objectives of the eXtraordinarY Kids Clinic program include prenatal genetic counseling, research, education, family support, and advocacy. Methods: Satisfaction surveys were distributed to 496 patients, and responses were received from 168 unique patients. Results: Satisfaction with the overall clinic visit was ranked as “very satisfied” in 85%, and as “satisfied” in another 9.8%. Results further demonstrate specific benefits from the clinic experience, the importance of a knowledgeable clinic coordinator, and support the need for similar clinics across the country. Three case examples of the interdisciplinary approach to assessment and

  1. eHealth technologies to support nutrition and physical activity behaviors in diabetes self-management

    Directory of Open Access Journals (Sweden)

    Rollo ME

    2016-11-01

    Full Text Available Megan E Rollo,1 Elroy J Aguiar,2 Rebecca L Williams,1 Katie Wynne,3 Michelle Kriss,3 Robin Callister,4 Clare E Collins1 1School of Health Sciences, Faculty of Health and Medicine, Priority Research Centre for Physical Activity and Nutrition, University of Newcastle, Callaghan, NSW, Australia; 2Department of Kinesiology, School of Public Health and Health Sciences, University of Massachusetts Amherst, Amherst, MA, USA; 3Department of Diabetes and Endocrinology, John Hunter Hospital, Hunter New England Health, New Lambton, NSW, Australia;\t4School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, Priority Research Centre for Physical Activity and Nutrition, University of Newcastle, Callaghan, NSW, Australia Abstract: Diabetes is a chronic, complex condition requiring sound knowledge and self-management skills to optimize glycemic control and health outcomes. Dietary intake and physical activity are key diabetes self-management (DSM behaviors that require tailored education and support. Electronic health (eHealth technologies have a demonstrated potential for assisting individuals with DSM behaviors. This review provides examples of technologies used to support nutrition and physical activity behaviors in the context of DSM. Technologies covered include those widely used for DSM, such as web-based programs and mobile phone and smartphone applications. In addition, examples of novel tools such as virtual and augmented reality, video games, computer vision for dietary carbohydrate monitoring, and wearable devices are provided. The challenges to, and facilitators for, the use of eHealth technologies in DSM are discussed. Strategies to support the implementation of eHealth technologies within practice and suggestions for future research to enhance nutrition and physical activity behaviors as a part of broader DSM are provided. Keywords: diabetes self-management, eHealth, nutrition, physical activity, smartphones, wearables

  2. Dabhol resumes

    International Nuclear Information System (INIS)

    Burr, M.T.

    1997-01-01

    Shockwaves were felt throughout the global business community when political forces in India stalled out the Dabhol power project. Lenders and investors felt even less secure about the risks involved with developing infrastructure projects in emerging economies, and Dabhol came to symbolize the sinkholes that lie in wait for even the best-devised projects with the strongest sponsors. The project resumed in early December, however, after the Bombay High Court dismissed the only remaining lawsuit filed against Dabhol Power Co. Now, the Dabhol project is set to become an example of how a project can succeed in a big way if it has developers with integrity, skill, flexibility, and--above all--a great deal of patience. Originally a 695 MW facility, Dabhol was renegotiated so the complex totals 2,450 MW, with one 740 MW phase and another 1,710 MW phase. open-quotes The additional capacity allowed us to recover the costs we incurred during cancellation,close quotes says Rebecca Mark, CEO of Enron Development Corp. in Houston, Texas. open-quotes We reduced rates for the second phase, and we'll handle it on a competitive basis when it comes to specifying equipment.close quotes Enron is the lead developer of the project, with an 80 percent equity stake. GE Capital of Stamford, Conn., USA, and Bechtel Enterprises of San Francisco, Calif., each hold a 10 percent share in the project. open-quotes The changes in the project have had little effect on the financing arrangements. Additional project costs which resulted from the delays were funded by the equity group, and the debt levels and terms remain consistent with those of the original closing,close quotes says Everett Smith III, executive vice president and director-international, for GE Capital Services Structured Finance Group

  3. A qualitative study examining methods of accessing and identifying research relevant to clinical practice among rehabilitation clinicians

    Directory of Open Access Journals (Sweden)

    Patel D

    2017-12-01

    Full Text Available Drasti Patel,1 Christine Koehmstedt,1 Rebecca Jones,1 Nathan T Coffey,1 Xinsheng Cai,2 Steven Garfinkel,2 Dahlia M Shaewitz,2 Ali A Weinstein1 1Center for Study of Chronic Illness and Disability, College of Health and Human Services, George Mason University, Fairfax, VA, 2American Institutes for Research, Washington, DC, USA Purpose: Research examining the utilization of evidence-based practice (EBP specifically among rehabilitation clinicians is limited. The objective of this study was to examine how various rehabilitative clinicians including physical therapists, occupational therapists, rehabilitation counselors, and physiatrists are gaining access to literature and whether they are able to implement the available research into practice.Methods: A total of 21 total clinicians were interviewed via telephone. Using NVivo, a qualitative analysis of the responses was performed.Results: There were similarities found with respect to the information-seeking behaviors and translation of research across the different clinician types. Lack of time was reported to be a barrier for both access to literature and implementation of research across all clinician types. The majority of clinicians who reported having difficulty with utilizing the published literature indicated that the literature was not applicable to their practice, the research was not specific enough to be put into practice, or the research found was too outdated to be relevant. In addition, having a supportive work environment aided in the search and utilization of research through providing resources central to assisting clinicians in gaining access to health information.Conclusion: Our study identified several barriers that affect EBP for rehabilitation clinicians. The findings suggest the need for researchers to ensure that their work is applicable and specific to clinical practice for implementation to occur. Keywords: health information, information behavior, knowledge utilization

  4. New Editor-in-Chief for Journal of Physics A: Mathematical and Theoretical

    Science.gov (United States)

    Gillan, Rebecca

    2014-04-01

    We are delighted to announce that Professor Martin Evans of University of Edinburgh has been appointed as the new Editor-in-Chief of Journal of Physics A: Mathematical and Theoretical. Martin Evans has been Editor of the Statistical Physics section of the journal since 2009. Prior to this, he served as a Board Member for the journal. His areas of research include statistical mechanics of nonequilibrium systems, phase transitions and scaling regimes in nonequilibrium statistical physics, glassy dynamics, phase transitions and ordering in driven diffusive systems, mass transport models, condensation models, zero range processes and exclusion processes. We very much look forward to working with Martin to continue to improve the journal's quality and interest to the readership. We would like to thank our outgoing Editor-in-Chief, Professor Murray Batchelor. Murray has worked hard and provided excellent guidance in improving the quality of the journal and the service that the journal provides to authors, referees and readers. During the last five years, we have raised the quality threshold for acceptance in the journal and currently reject over 70% of submissions. As a result, papers published in Journal of Physics A: Mathematical and Theoretical are amongst the best in the field. We have also maintained and improved on our excellent receipt-to-first-decision times, which now average under 40 days for papers. With the help of Martin Evans and our distinguished Editorial Board, we will be working to further improve the quality of the journal whilst continuing to offer excellent services to our readers, authors and referees. We hope that you benefit from reading the journal. If you have any comments or questions, please do not hesitate to contact us at jphysa@iop.org. Rebecca Gillan Publisher

  5. Evolutionary thinking: "A conversation with Carter Phipps about the role of evolutionary thinking in modern culture".

    Science.gov (United States)

    Hunt, Tam

    2014-12-01

    Evolution as an idea has a lengthy history, even though the idea of evolution is generally associated with Darwin today. Rebecca Stott provides an engaging and thoughtful overview of this history of evolutionary thinking in her 2013 book, Darwin's Ghosts: The Secret History of Evolution. Since Darwin, the debate over evolution-both how it takes place and, in a long war of words with religiously-oriented thinkers, whether it takes place-has been sustained and heated. A growing share of this debate is now devoted to examining how evolutionary thinking affects areas outside of biology. How do our lives change when we recognize that all is in flux? What can we learn about life more generally if we study change instead of stasis? Carter Phipps' book, Evolutionaries: Unlocking the Spiritual and Cultural Potential of Science's Greatest Idea, delves deep into this relatively new development. Phipps generally takes as a given the validity of the Modern Synthesis of evolutionary biology. His story takes us into, as the subtitle suggests, the spiritual and cultural implications of evolutionary thinking. Can religion and evolution be reconciled? Can evolutionary thinking lead to a new type of spirituality? Is our culture already being changed in ways that we don't realize by evolutionary thinking? These are all important questions and Phipps book is a great introduction to this discussion. Phipps is an author, journalist, and contributor to the emerging "integral" or "evolutionary" cultural movement that combines the insights of Integral Philosophy, evolutionary science, developmental psychology, and the social sciences. He has served as the Executive Editor of EnlightenNext magazine (no longer published) and more recently is the co-founder of the Institute for Cultural Evolution, a public policy think tank addressing the cultural roots of America's political challenges. What follows is an email interview with Phipps.

  6. Simulation-Augmented Methods for Safe and Efficient Manoeuvres in Harbour Areas

    Directory of Open Access Journals (Sweden)

    Knud Benedict

    2016-07-01

    manoeuvring time by a very complex ship-dynamic simulation model for rudder, engine and thruster manoeuvres. It enables prompt prediction of all manoeuvres carried out by the conning officer for the observing officer, too. Predictions of path and motion status allow all officers to see whether the manoeuvring actions have at least the correct tendency or indicating the need for corrections. This new type of support is called Simulation-Augmented Manoeuvring Design and Monitoring (SAMMON – it allows not only overlooking the next manoeuvring segment ahead but also for the following or even for series of manoeuvring segments. This technology has been used within two research projects: COSINUS (Co-operative Ship Operation in Integrated Maritime Traffic Systems set out for implementing FTS into integrated ship bridges and to also communicate the manoeuvre plans and display it to VTS centres. Within the European project MUNIN (Maritime Unmanned Navigation through Intelligence in Networks this technology has been used to investigate if it is possible to steer autonomous ships, in case it would be necessary.

  7. Proactive strategies for regorafenib in metastatic colorectal cancer: implications for optimal patient management

    Directory of Open Access Journals (Sweden)

    Khan G

    2014-03-01

    Full Text Available Gazala Khan,1 Rebecca A Moss,2 Fadi Braiteh,3,4 Marc Saltzman5 1Department of Hematology and Oncology, Henry Ford Hospital, Detroit, MI, USA; 2Rutgers Cancer Institute of New Jersey, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA; 3US Oncology Research, Las Vegas, NV, USA; 4Comprehensive Cancer Centers of Nevada, Las Vegas, NV, USA; 5Innovative Medical Research of South Florida, Inc, Aventura, FL, USA Abstract: Regorafenib is a broad-spectrum oral multikinase inhibitor that targets several angiogenic, oncogenic, and stromal receptor tyrosine kinases that support the tumor microenvironment. Results from the pivotal Phase III Patients with Metastatic Colorectal Cancer Treated with Regorafenib or Placebo After Failure of Standard Therapy (CORRECT trial showed that the addition of regorafenib to best supportive care resulted in a significant improvement in median overall survival and progression-free survival compared with placebo plus best supportive care in patients with metastatic colorectal cancer (mCRC following all available approved therapies. Thus, regorafenib is the first oral multikinase inhibitor indicated for mCRC; it currently has approval in the USA, EU, Japan, Canada, and Singapore for the treatment of mCRC patients who have been previously treated with fluoropyrimidine-, oxaliplatin-, and irinotecan-based chemotherapy, an anti-vascular endothelial growth factor therapy, and, if the tumor is KRAS wild-type, an anti-epidermal growth factor receptor therapy. In this review, we highlight regorafenib's mechanism of action, present key efficacy data from the CORRECT trial, and discuss how to proactively manage common adverse events (eg, hand-foot skin reaction, hypertension, oral mucositis, diarrhea, and fatigue experienced by patients receiving regorafenib. Increased awareness of potential adverse events associated with regorafenib and the implementation of proactive strategies to prevent, monitor, and manage these

  8. Nuclear Crisis Communications: The Plan Worked. A Critique of NRC Communications in the Fukushima Daiichi Reactor Crisis - 12073

    Energy Technology Data Exchange (ETDEWEB)

    Brenner, Eliot; Harrington, Holly; Schmidt, Rebecca [U.S. Nuclear Regulatory Commission, Rockville, MD 20852 (United States)

    2012-07-01

    'Call the AV-Photo folks and get someone in here to shoot b-roll. We'll never be able to accommodate the network cameras and the only way I can get this to the media is to produce it ourselves'. Eliot Brenner, Director NRC Office of Public Affairs, March 12, 2011. For the past four years we have been speaking to audiences at Waste Management about communications issues. Last year, though we were kept from attending because of the federal budget crisis, our surrogates described to you the lessons the nuclear industry should draw from the BP Gulf oil spill crisis. Those remarks were delivered 11 days before the Fukushima Daiichi tragedy became the nuclear landmark of a generation - an industry changing event with worldwide ramifications, both in science and regulation and in communications. Eliot Brenner cut his teeth on crisis communication in the aviation industry where tragedy unfolds rapidly. He has been a speech-writer to three cabinet secretaries, spokesman for the Federal Aviation Administration and now spokesman for the Nuclear Regulatory Commission since 2004. Holly Harrington manages the NRC crisis response program and has 26 years federal public affairs experience, including eight years at the Federal Emergency Management Agency. Her crisis experience includes the 1989 Loma Prieta earthquake, numerous hurricanes and floods, Sept 11, and, now Fukushima Daiichi. Rebecca Schmidt is a veteran government relations professional whose decades in Washington include service with the House Armed Services Committee, the House Budget Committee and the Secretary of Defense. Collectively, the Offices of Public Affairs and Congressional Affairs conducted the largest outreach for the agency since Three Mile Island. We worked with the basic rule, described to Waste Management last year just 11 days before Fukushima - communicate early, often and clearly. The response - while not without its problems and lessons - went as smoothly as a chaotic event like

  9. Does information form matter when giving tailored risk information to patients in clinical settings? A review of patients’ preferences and responses

    Directory of Open Access Journals (Sweden)

    Harris R

    2017-03-01

    Full Text Available Rebecca Harris, Claire Noble, Victoria Lowers Institute of Psychology, Health and Society, University of Liverpool, Liverpool, UK Abstract: Neoliberal emphasis on “responsibility” has colonized many aspects of public life, including how health care is provided. Clinical risk assessment of patients based on a range of data concerned with lifestyle, behavior, and health status has assumed a growing importance in many health systems. It is a mechanism whereby responsibility for self (preventive care can be shifted to patients, provided that risk assessment data is communicated to patients in a way which is engaging and motivates change. This study aimed to look at whether the form in which tailored risk information was presented in a clinical setting (for example, using photographs, online data, diagrams etc., was associated with differences in patients’ responses and preferences to the material presented. We undertook a systematic review using electronic searching of nine databases, along with handsearching specialist journals and backward and forward citation searching. We identified eleven studies (eight with a randomized controlled trial design. Seven studies involved the use of computerized health risk assessments in primary care. Beneficial effects were relatively modest, even in studies merely aiming to enhance patient–clinician communication or to modify patients’ risk perceptions. In our paper, we discuss the apparent importance of the accompanying discourse between patient and clinician, which appears to be necessary in order to impart meaning to information on “risk,” irrespective of whether the material is personalized, or even presented in a vivid way. Thus, while expanding computer technologies might be able to generate a highly personalized account of patients’ risk in a time efficient way, the need for face-to-face interactions to impart meaning to the data means that these new technologies cannot fully address the

  10. Book Reviews

    Directory of Open Access Journals (Sweden)

    Christien Klaufus, Book Review Editor

    2016-04-01

    Full Text Available The Improbable Conquest: Sixteenth Century Letters from the Rio de la Plata, por Pablo García Loaeza y Victoria L. Garrett, 2015; reseñado por Judith Farberman Urban Space as Heritage in Late Colonial Cuba: Classicism and Dissonance on the Plaza de Armas of Havana: 1754-1828, by Paul Niell, 2015; reviewed by Joseph L. Scarpaci El Jefe Político. Un dominio negociando en el mundo rural del Estado de México. 1856-1911, por Romana Falcón, 2015; reseñado por Raymond Buve Miedo negro, poder blanco en la Cuba colonial, por Jorge Camacho, 2015; reseñado por Oleski Miranda Navarro Revolutionary Parks: Conservation, Social Justice, and Mexico’s National Parks, 1910-1940, by Emily Wakild, 2011; reviewed by Grant Burrier Sandino’s Nation: Ernesto Cardenal and Sergio Ramírez Writing Nicaragua, 1940-2012, by Stephen Henighan, 2014; reviewed by Grace A. Gomashie La cancha peronista. Fútbol y política (1946-1955, edited by Raanan Rein, 2015; reviewed by Alexis Sossa Rojas Chile y la Guerra Fría global, edited by Tanya Harmer and Alfredo Riquelme Segovia, 2014; reviewed by Ángela Vergara Challenging Social Inequality: The Landless Rural Workers Movement and Agrarian Reform in Brazil, edited by M. Carter, 2015; reviewed by Rebecca Tarlau Brazil: Reversal of Fortune, by Alfred P. Montero, 2014; reviewed by Edgar J. Marcolin Latin American Documentary Filmmaking – Major works, by David William Foster, 2013; reviewed by Leontien Cremers Telling and Being told: Storytelling and Cultural Control in Contemporary Yucatec Maya Literatures, por Paul Worley, 2013; reseñado por Ana Ugarte Bachata and Dominican Identity/La bachata y la identidad dominicana, by Julie Sellers, 2014; reviewed by Grant D. Moss Entrepreneurial Selves: Neoliberal Respectability and the Making of a Caribbean Middle Class, by Carla Freeman, 2014; reviewed by Emiel Martens

  11. Blastic plasmacytoid dendritic cell neoplasm with absolute monocytosis at presentation

    Directory of Open Access Journals (Sweden)

    Jaworski JM

    2015-02-01

    Full Text Available Joseph M Jaworski,1,2 Vanlila K Swami,1 Rebecca C Heintzelman,1 Carrie A Cusack,3 Christina L Chung,3 Jeremy Peck,3 Matthew Fanelli,3 Micheal Styler,4 Sanaa Rizk,4 J Steve Hou1 1Department of Pathology and Laboratory Medicine, Hahnemann University Hospital/Drexel University College of Medicine, Philadelphia, PA, USA; 2Department of Pathology, Mercy Fitzgerald Hospital, Darby, PA, USA; 3Department of Dermatology, Hahnemann University Hospital/Drexel University College of Medicine, Philadelphia, PA, USA; 4Department of Hematology/Oncology, Hahnemann University Hospital/Drexel University College of Medicine, Philadelphia, PA, USA Abstract: Blastic plasmacytoid dendritic cell neoplasm is an uncommon malignancy derived from precursors of plasmacytoid dendritic cells. Nearly all patients present initially with cutaneous manifestations, with many having extracutaneous disease additionally. While response to chemotherapy initially is effective, relapse occurs in most, with a leukemic phase ultimately developing. The prognosis is dismal. While most of the clinical and pathologic features are well described, the association and possible prognostic significance between peripheral blood absolute monocytosis (>1.0 K/µL and blastic plasmacytoid dendritic cell neoplasm have not been reported. We report a case of a 68-year-old man who presented with a rash for 4–5 months. On physical examination, there were multiple, dull-pink, indurated plaques on the trunk and extremities. Complete blood count revealed thrombocytopenia, absolute monocytosis of 1.7 K/µL, and a negative flow cytometry study. Biopsy of an abdominal lesion revealed typical features of blastic plasmacytoid dendritic cell neoplasm. Patients having both hematologic and nonhematologic malignancies have an increased incidence of absolute monocytosis. Recent studies examining Hodgkin and non-Hodgkin lymphoma patients have suggested that this is a negative prognostic factor. The association between

  12. Multicentric osteolysis with nodulosis, arthritis, and cardiac defect syndrome: loss of MMP2 leads to increased apoptosis with alteration of apoptotic regulators and caspases and embryonic lethality

    Directory of Open Access Journals (Sweden)

    Mosig RA

    2014-11-01

    Full Text Available Rebecca A Mosig,1 Richard Schulz,2,3 Zamaneh Kassiri,4 Mitchell B Schaffler,5 John A Martignetti1 1Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA; 2Department of Pharmacology; 3Department of Pediatrics, 4Department of Physiology, Cardiovascular Research Centre, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, AB, Canada; 5Department of Biomedical Engineering, City College of New York, New York, NY, USA Abstract: Inactivating mutations of matrix metalloproteinase 2 (MMP2 cause multicentric osteolysis with nodulosis and arthritis, one of a group of inherited osteolytic and arthritic disorders. We have previously shown that mice lacking Mmp2 share similar syndromic features with the human disorder, and at the cellular level, Mmp2-/- mouse osteoblasts and osteoclasts have reduced numbers and proliferation rates at critical developmental time points. While previously hypothesized, the effect of MMP2 loss on apoptosis has not been examined in this system. We therefore sought to clarify its role in mediating the developmental defects in Mmp2-/- mice using immunohistochemistry, immunoblot analysis, and quantitative reverse transcription polymerase chain reaction analysis. We also explored the effects of MMP2 inhibition in the osteogenic sarcoma cell line SaOS2. Loss of MMP2 resulted in increased apoptosis and caspase activation both in vitro and in vivo. MMP2-deficient cells had increased Fas expression and reduced levels of the key survival signals p-FAK, p-ERK, cFLIP, and Bcl-2. Notably, and in marked contrast to their original characterization, there was a significant increase in the in utero demise of homozygous Mmp2-/- embryos. Specifically, litters from heterozygous crosses consistently yielded nearly 85% fewer than expected homozygous Mmp2-/- pups. Taken together, our findings highlight a new role for MMP2 in preventing apoptosis during development and growth. Keywords

  13. Canadian Rheumatology Association Meeting, The Westin Ottawa, Ottawa, Ontario, Canada, February 8-11, 2017.

    Science.gov (United States)

    Silverman, Earl D

    2017-05-01

    The 72nd Annual Meeting of The Canadian Rheumatology Association (CRA) was held at The Westin Ottawa, Ottawa, Ontario, Canada, February 8-11, 2017. The program consisted of presentations covering original research, symposia, awards, and lectures. Highlights of the meeting include the following 2017 award winners: Dr. Vinod Chandran, Young Investigator; Dr. Jacques P. Brown, Distinguished Investigator; Dr. David Robinson, Teacher-Educator; Dr. Michel Zummer, Distinguished Rheumatologist; Ms. Rebecca Gole, Best Abstract on SLE Research by a Trainee - Ian Watson Award; Ms. Bailey Russell, Best Abstract on Clinical or Epidemiology Research by a Trainee - Phil Rosen Award; Dr. Sahil Koppikar and Dr. Henry Averns, Practice Reflection Award; Dr. Shirine Usmani, Best Abstract on Basic Science Research by a Trainee; Ms. Carol Dou, Best Abstract for Research by an Undergraduate Student; Dr. Dania Basodan, Best Abstract on Research by a Rheumatology Resident; Dr. Claire Barber, Best Abstract on Adult Research by Young Faculty; Ms. Audrea Chen, Best Abstract by a Medical Student; Dr. Kun Huang, Best Abstract by a Post-Graduate Resident; and Dr. Ryan Lewinson, Best Abstract by a Post-Graduate Research Trainee. Lectures and other events included a Keynote Lecture by Jonathon Fowles: Exercise is Medicine: Is Exercise a Good or Bad Thing for People with Arthritis?; State of the Art Lecture by Matthew Warman: Insights into Bone Biology and Therapeutics Gleaned from the Sustained Investigation of Rare Diseases; Dunlop-Dottridge Lecture by Allen Steere: Lyme Disease: A New Problem for Rheumatologists in Canada; and the Great Debate: Be it Resolved that the Least Expensive Treatment Should be Chosen. Switch, Switch, Switch! Arguing for: Jonathan Chan and Antonio Avina, and against: Marinka Twilt and Glen Hazlewood. Topics such as rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, Sjögren syndrome, psoriatic arthritis, spondyloarthritis, vasculitis, osteoarthritis

  14. Mental Health Mobile Apps for Preadolescents and Adolescents: A Systematic Review.

    Science.gov (United States)

    Grist, Rebecca; Porter, Joanna; Stallard, Paul

    2017-05-25

    evaluating their safety, efficacy, and effectiveness is promptly needed. ©Rebecca Grist, Joanna Porter, Paul Stallard. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 25.05.2017.

  15. Effects of tai chi chuan on anxiety and sleep quality in young adults: lessons from a randomized controlled feasibility study

    Directory of Open Access Journals (Sweden)

    Caldwell KL

    2016-11-01

    Full Text Available Karen L Caldwell,1 Shawn M Bergman,2 Scott R Collier,3 N Travis Triplett,3 Rebecca Quin,4 John Bergquist,5 Carl F Pieper6 1Department of Human Development and Psychological Counseling, 2Department of Psychology, 3Department of Health and Exercise Science, 4Department of Theatre and Dance, 5Department of Psychology, Appalachian State University, Boone, 6Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC, USA Objective: To determine feasibility and estimate the effect of a 10-week tai chi chuan (TCC intervention on anxiety and sleep quality in young adults. Participants: Seventy-five adults (18–40 years from a predominately undergraduate mid-sized university. Methods: This was an assessor blinded, randomized feasibility trial, and participants were randomized into one of three groups: 10 weeks of TCC meeting 2 times per week, 10 weeks of TCC with a DVD of the curriculum, and control group receiving a handout on anxiety management. Anxiety and sleep quality were assessed 4 times: baseline, 4 weeks, 10 weeks (immediate post-intervention, and 2 months post-intervention. Retention was defined as a participant attending the baseline assessment and at least one other assessment. Adherence to the intervention was set a priori as attendance at 80% of the TCC classes. Results: Eighty-five percent of participants were retained during the intervention and 70% completed the 2 month follow-up assessments. To increase statistical power, the two TCC groups were combined in the analyses of anxiety and sleep quality measures. No significant changes in anxiety were found in the control group, while levels of anxiety decreased significantly over time in the two TCC groups. Sleep quality scores improved across time for all three groups, but adherent TCC participants reported greater improvement than control participants. Conclusion: TCC may be an effective nonpharmaceutical means of improving anxiety and poor sleep quality

  16. Development of hypertension in overweight adolescents: a review

    Directory of Open Access Journals (Sweden)

    Kelly RK

    2015-10-01

    Full Text Available Rebecca K Kelly,1 Costan G Magnussen,1,2 Matthew A Sabin,3 Michael Cheung,3 Markus Juonala3–5 1Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia; 2Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland; 3Murdoch Childrens Research Institute, Royal Children's Hospital and University of Melbourne, Parkville, Australia; 4Department of Medicine, University of Turku, 5Division of Medicine, Turku University Hospital, Turku, Finland Abstract: The upward trend in adolescent hypertension is widely attributed to the adolescent obesity epidemic. Secular trends in adolescent prehypertension and hypertension have risen in congruence with increasing trends in the prevalence of overweight and obesity. The correlation between body mass index and blood pressure in adolescence is moderate to strong in most studies and strongest in those classified as overweight or obese. The mechanisms relating to the development of hypertension in overweight adolescents are unclear; however, a number of nonmodifiable and modifiable factors have been implicated. Importantly, certain clinical and biochemical markers in overweight adolescents are indicative of high risk for hypertension, including family history of hypertension and hyperinsulinemia. These characteristics may prove useful in stratifying overweight adolescents as high or low risk of comorbid hypertension. The treatment of overweight and obesity related hypertension in this population focuses on two key modalities: lifestyle change and pharmacotherapy. These approaches focus almost exclusively on weight reduction; however, a number of emerging strategies target hypertension more specifically. Among adolescents with overt hypertension there are also several factors that indicate higher risk of concurrent subclinical disease, persistent adult hypertension, and adult cardiovascular disease. This group may benefit substantially from more

  17. An optimized probucol microencapsulated formulation integrating a secondary bile acid (deoxycholic acid as a permeation enhancer

    Directory of Open Access Journals (Sweden)

    Mooranian A

    2014-09-01

    Full Text Available Armin Mooranian,1 Rebecca Negrulj,1 Nigel Chen-Tan,2 Gerald F Watts,3 Frank Arfuso,4 Hani Al-Salami11Biotechnology and Drug Development Research Laboratory, School of Pharmacy, Curtin Health Innovation Research Institute, Biosciences Research Precinct, Curtin University, 2Faculty of Science and Engineering, Curtin University, 3School of Medicine and Pharmacology, Royal Perth Hospital, University of Western Australia, 4School of Biomedical Science, Curtin Health Innovation Research Institute, Biosciences Research Precinct, Curtin University, Perth, AustraliaAbstract: The authors have previously designed, developed, and characterized a novel microencapsulated formulation as a platform for the targeted delivery of therapeutics in an animal model of type 2 diabetes, using the drug probucol (PB. The aim of this study was to optimize PB microcapsules by incorporating the bile acid deoxycholic acid (DCA, which has good permeation-enhancing properties, and to examine its effect on microcapsules’ morphology, rheology, structural and surface characteristics, and excipients’ chemical and thermal compatibilities. Microencapsulation was carried out using a BÜCHI-based microencapsulating system established in the authors’ laboratory. Using the polymer sodium alginate (SA, two microencapsulated formulations were prepared: PB-SA (control and PB-DCA-SA (test at a constant ratio (1:30 and 1:3:30, respectively. Complete characterization of the microcapsules was carried out. The incorporation of DCA resulted in better structural and surface characteristics, uniform morphology, and stable chemical and thermal profiles, while size and rheological parameters remained similar to control. In addition, PB-DCA-SA microcapsules showed good excipients’ compatibilities, which were supported by data from differential scanning calorimetry, Fourier transform infrared spectroscopy, scanning electron microscopy, and energy dispersive X-ray studies, suggesting

  18. High maternal and neonatal mortality rates in northern Nigeria: an 8-month observational study

    Directory of Open Access Journals (Sweden)

    Guerrier G

    2013-08-01

    Full Text Available Gilles Guerrier,1 Bukola Oluyide,2 Maria Keramarou,1 Rebecca Grais1 1Epicentre, Paris, France; 2Médecins Sans Frontières, Paris, France Background: Despite considerable efforts to reduce the maternal mortality ratio, numerous pregnant women continue to die in many developing countries, including Nigeria. We conducted a study to determine the incidence and causes of maternal mortality over an 8-month period in a rural-based secondary health facility located in Jahun, northern Nigeria. Methods: A retrospective observational study was performed in a 41-bed obstetric ward. From October 2010 to May 2011, demographic data, obstetric characteristics, and outcome were collected from all pregnant women admitted. The total number of live births during the study period was recorded in order to calculate the maternal mortality ratio. Results: There were 2,177 deliveries and 39 maternal deaths during the study period, with a maternal mortality ratio of 1,791/100,000 live births. The most common causes of maternal mortality were hemorrhage (26%, puerperal sepsis (19%, and obstructed labor (5%. No significant difference (P = 0.07 in mean time to reach the hospital was noted between fatal cases (1.9 hours, 95% confidence interval [CI] 1.1–2.6 and nonfatal cases (1.4 hours, 95% CI 1.4–1.5. Two hundred and sixty-six women were admitted presenting with stillbirth. Maternal mortality was higher for unbooked patients than for booked patients (odds ratio 5.1, 95% CI 3.5–6.2, P < 0.0001. The neonatal mortality rate was calculated at 46/1,000 live births. The main primary causes of neonatal deaths were prematurity (44% and birth asphyxia (22%. Conclusion: Maternal and neonatal mortality remains unacceptably high in this setting. Reducing unbooked emergencies should be a priority with continuous programs including orthodox practices in order to meet the fifth Millennium Development Goal. Keywords: fetal mortality, maternal mortality, Nigeria, antenatal care

  19. Permissive tolerance of the patent ductus arteriosus may increase the risk of Chronic Lung Disease

    Directory of Open Access Journals (Sweden)

    Kaempf JW

    2013-03-01

    Full Text Available Joseph W Kaempf,1 Robert Huston,2 YingXing Wu,1 Andrew J Kaempf,1 Lian Wang,1 Gary Grunkemeier,1 Rebecca Mischel,2 Howard Cohen,3 Bret Freitag41Providence St Vincent Medical Center, Portland, OR, 2Randall Children’s Hospital at Legacy Emanuel, Portland, OR, 3Salem Hospital, Salem, OR, 4Legacy Salmon Creek Hospital, Vancouver, WA, USAPurpose: Because early closure therapies of the patent ductus arteriosus (PDA have not been shown to confer benefit to premature infants, the authors’ four neonatal intensive care units adopted a less aggressive PDA management protocol.Study design: A before–after investigation in infants with PDAs born 501–1500 g. Era 1 (January 2005 to December 2007 featured traditional management with indomethacin and/or surgical ligation used early to close PDAs; Era 2 (January 2008 to June 2009 featured fluid restriction and watchful waiting for PDA closure, limiting indomethacin or surgical ligation to only those infants with large PDAs needing significant respiratory support.Results: Era 2 infants (n = 129, mean ± standard deviation 27 ± 2 weeks received less and later indomethacin and less Day 1–28 total fluids as compared to Era 1 infants (n = 240, mean ± standard deviation 27 ± 2 weeks. The Chronic Lung Disease (CLD rate was higher in Era 2 (48% versus 34%, P < 0.01 as was the combined outcome of Death after Day 7 or CLD (57% versus 42%, P < 0.01. Multiple regression analysis showed Era 2 birth was a predictor of CLD. However, Poisson regression analysis determined the predictors of all seven major Vermont Oxford Network morbidities were earlier gestational age, lower birth weight, and male gender, not the era of birth. Significantly more infants were discharged home with PDAs in Era 2.Conclusion: Permissive tolerance of PDAs may increase the risk of CLD and Death after Day 7 or CLD but is not associated with significant changes in other Vermont Oxford Network morbidities.Keywords: premature infant

  20. Swallowing difficulties with medication intake assessed with a novel self-report questionnaire in patients with systemic sclerosis – a cross-sectional population study

    Directory of Open Access Journals (Sweden)

    Messerli M

    2017-09-01

    Full Text Available Markus Messerli,1,2 Rebecca Aschwanden,1 Michael Buslau,2 Kurt E Hersberger,1 Isabelle Arnet1 1Pharmaceutical Care Research Group, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland; 2European Centre for the Rehabilitation of Scleroderma, Reha Rheinfelden, Rheinfelden, Switzerland Objectives: To assess subjective swallowing difficulties (SD with medication intake and their practical consequences in patients suffering from systemic sclerosis (SSc with a novel self-report questionnaire.Design and setting: Based on a systematic literature review, we developed a self-report questionnaire and got it approved by an expert panel. Subsequently, we sent the questionnaire by post mail to SSc patients of the European Center for the Rehabilitation of Scleroderma Rheinfelden, Switzerland.Participants: Patients were eligible if they were diagnosed with SSc, treated at the center, and were of age ≥18 years at the study start.Main outcome measures: Prevalence and pattern of SD with oral medication intake, including localization and intensity of complaints.Results: The questionnaire consisted of 30 items divided into five sections Complaints, Intensity, Localization, Coping strategies, and Adherence. Of the 64 SSc patients eligible in 2014, 43 (67% returned the questionnaire. Twenty patients reported SD with medication intake (prevalence 47%, either currently (11; 26% or in the past that had been overcome (9; 21%. Self-reported SD were localized mostly in the larynx (43% and esophagus (34%. They were of moderate (45% or strong to unbearable intensity (25%. Modification of the dosage form was reported in 40% of cases with SD. Adherence was poor for 20 (47% patients and was not associated with SD (p=0.148.Conclusion: Our novel self-report questionnaire is able to assess the pattern of complaints linked to medication intake, that is, localization and intensity. It may serve as a guide for health care professionals in selecting the most

  1. Clinical effects of prior trastuzumab on combination eribulin mesylate plus trastuzumab as first-line treatment for human epidermal growth factor receptor 2 positive locally recurrent or metastatic breast cancer: results from a Phase II, single-arm, multicenter study

    Directory of Open Access Journals (Sweden)

    Puhalla S

    2016-12-01

    Full Text Available Shannon Puhalla,1 Sharon Wilks,2 Adam M Brufsky,1 Joyce O’Shaughnessy,3 Lee S Schwartzberg,4 Erhan Berrak,5 James Song,5 Linda Vahdat6 1Department of Hematology and Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA, 2Department of Hematology Oncology, US Oncology-Cancer Care Centers of South Texas, San Antonio, TX, 3Department of Medical Oncology, Texas Oncology-Baylor Charles A. Sammons Cancer Center US Oncology, Dallas, TX, 4Department of Hematology/Oncology, West Cancer Center, University of Tennessee Health Science Center, Memphis, TN, 5Department of Medical Affairs, Formerly of Eisai Inc., Woodcliff Lake, NJ, 6Department of Medicine, Weill Cornell Medical College, New York, NY, USA Abstract: Eribulin mesylate, a novel nontaxane microtubule dynamics inhibitor in the halichondrin class of antineoplastic drugs, is indicated for the treatment of patients with metastatic breast cancer who previously received ≥2 chemotherapy regimens in the metastatic setting. Primary data from a Phase II trial for the first-line combination of ­eribulin plus trastuzumab in human epidermal growth factor receptor 2 positive patients showed a 71% objective response rate and tolerability consistent with the known profile of these agents. Here, we present prespecified analyses of efficacy of this combination based on prior trastuzumab use. Patients received eribulin mesylate 1.4 mg/m2 (equivalent to 1.23 mg/m2 eribulin [expressed as free base] intravenously on days 1 and 8 plus trastuzumab (8 mg/kg intravenously/cycle 1, then 6 mg/kg on day 1 of each 21-day cycle. Objective response rates, progression-free survival, and tolerability were assessed in patients who had and had not received prior adjuvant or neoadjuvant (neo/adjuvant trastuzumab treatment. Fifty-two patients (median age: 59.5 years received eribulin/trastuzumab for a median treatment duration of ~31 weeks; 40.4% (n=21 had been previously treated with neo/adjuvant trastuzumab prior to

  2. SGLT-2 inhibitors and their potential in the treatment of diabetes

    Directory of Open Access Journals (Sweden)

    Rosenwasser RF

    2013-11-01

    Full Text Available Rebecca F Rosenwasser,1 Senan Sultan,2 David Sutton,2 Rushab Choksi,1 Benjamin J Epstein3 1East Coast Institute for Research, Jacksonville, FL, USA; 2Northeast Florida Endocrine and Diabetes Associates, Jacksonville, FL, USA; 3Department of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, FL, USA Abstract: Diabetes remains a burgeoning global problem, necessitating ongoing efforts on the part of pharmaceutical and device manufacturers, patients, and society to curb the frightening trends in morbidity and mortality attributable to the malady. Since 1835 when phlorizin was discovered, sodium glucose co-transporter 2 (SGLT-2 inhibitors have rested tantalizingly on the horizon, promising a more physiological approach to glucose control. These agents lower glucose by enhancing its excretion by blocking reabsorption in the renal tubules, thus eliminating glucose from the body along with the molecules' attendant effects on caloric balance, plasma osmolality, and lipids. Consequently, SGLT-2 inhibitors improve glucose control to an extent comparable to other hypoglycemic agents while simultaneously reducing body weight, blood pressure, and cholesterol – an admirable portfolio. One agent, canagliflozin, has recently been approved by the US Food and Drug Administration (FDA and two other agents have progressed through Phase III trials, including dapagliflozin and empagliflozin. Collectively, when used as monotherapy, these agents have demonstrated reductions in hemoglobin A1c (HbA1c, body weight, and blood pressure of –0.34% to –1.03%, –2.0 to -3.4 kg, and –1.7 to –6.4 mmHg/–0.3 to –2.6 mmHg (systolic blood pressure/diastolic blood pressure, respectively. SGLT-2 inhibitors have been well tolerated, with hypoglycemia (0.9% to 4.3% occurring infrequently in clinical trials. Safety signals related to breast and bladder cancer have arisen with dapagliflozin, though these are unsubstantiated

  3. Inventing Wastewater: The Social and Scientific Construction of Effluent in the Northeastern United States

    Science.gov (United States)

    Brideau, J. M.; Ng, M.; Hoover, J. H.; Hale, R. L.; Thomas, B.; Vogel, R. M.; Northeast ConsortiumHydrologic Synthesis Summer Institute, 2010--Biogeochemistry

    2010-12-01

    Title: Inventing Wastewater: The Social and Scientific Construction of Effluent in the Northeastern United States Authors: Jeffrey Brideau, Melissa Ng, Joseph Hoover, Rebecca Hale, Brian Thomas, and Richard Vogel Presented by: Jeffrey Brideau B.A., M.A., PhD Candidate, Department of History, University of Maryland Regulation of pollution is a prevalent part of contemporary American society. Scientists and policy makers have established acceptable effluent thresholds, with the ostensible goal of protecting human and stream health. However, this ubiquity of regulation is a recent phenomenon, and institutional mechanisms for effluent control were virtually non-existent in the early 20th century. Nonetheless, these same decades witnessed the emergence of nascent efforts at water pollution abatement. This project aims to explore social and scientific perceptions of wastewater, and begins with the simple premise that socio-cultural values underlay human decision-making in water management, and that wastewater is imbued with a matrix of human values that are continuously renegotiated. So what were the primary motivations for abatement efforts? Were they aesthetic and olfactory, or scientific concern for public and stream health? This paper proposes that there are social as well as scientific thresholds for pollutant loads. Collaborating with a team of interdisciplinary researchers we have created and aggregated discrete data sets to model, using export coefficient and linear regression modeling techniques, historic pollutant loading in the Northeastern United States. Concurrently, we have drawn on historical narratives of agitation by abatement advocates, nuisance laws, regulatory regimes, and changing scientific understanding; and contrasting the modeling results with these narratives allows this project to quantitatively determine where social thresholds lay in relation to their scientific counterparts. This project’s novelty lies in its use of existing narratives of

  4. A systematic review of interventions conducted in clinical or community settings to improve dual-task postural control in older adults

    Directory of Open Access Journals (Sweden)

    Agmon M

    2014-03-01

    Full Text Available Maayan Agmon,1 Basia Belza,2 Huong Q Nguyen,2,3 Rebecca G Logsdon,2 Valerie E Kelly41The Cheryl Spencer Department of Nursing, Faculty of Social Welfare and Health Studies, University of Haifa, Israel; 2School of Nursing, University of Washington, Seattle, WA, USA; 3Department of Research and Evaluation, Kaiser Permanente, CA, USA; 4School of Medicine, University of Washington, Seattle, WA, USABackground: Injury due to falls is a major problem among older adults. Decrements in dual-task postural control performance (simultaneously performing two tasks, at least one of which requires postural control have been associated with an increased risk of falling. Evidence-based interventions that can be used in clinical or community settings to improve dual-task postural control may help to reduce this risk.Purpose: The aims of this systematic review are: 1 to identify clinical or community-based interventions that improved dual-task postural control among older adults; and 2 to identify the key elements of those interventions.Data sources: Studies were obtained from a search conducted through October 2013 of the following electronic databases: PubMed, CINAHL, PsycINFO, and Web of Science.Study selection: Randomized and nonrandomized controlled studies examining the effects of interventions aimed at improving dual-task postural control among community-dwelling older adults were selected.Data extraction: All studies were evaluated based on methodological quality. Intervention characteristics including study purpose, study design, and sample size were identified, and effects of dual-task interventions on various postural control and cognitive outcomes were noted.Data synthesis: Twenty-two studies fulfilled the selection criteria and were summarized in this review to identify characteristics of successful interventions.Limitations: The ability to synthesize data was limited by the heterogeneity in participant characteristics, study designs, and outcome

  5. Development of patient-centric linguistically tailored psychoeducational messages to support nutrition and medication self-management in type 2 diabetes: a feasibility study

    Directory of Open Access Journals (Sweden)

    Ellis RJB

    2014-10-01

    Full Text Available Rebecca J Bartlett Ellis,1 Ulla Connor,2 James Marshall21Indiana University School of Nursing, 2Indiana University School of Liberal Arts, International Center for Intercultural Communication, Indiana University, Indianapolis, IN, USA Purpose: This study evaluated the feasibility of developing linguistically tailored educational messages designed to match the linguistic styles of patients segmented into types with the Descriptor™, and to determine patient preferences for tailored or standard messages based on their segments. Patients and methods: Twenty patients with type 2 diabetes (T2DM were recruited from a diabetes health clinic. Participants were segmented using the Descriptor™, a language-based questionnaire, to identify patient types based on their control orientation (internal/external, agency (high/low, and affect (positive/negative, which are well studied constructs related to T2DM self-management. Two of the seven self-care behaviors described by the American Association of Diabetes Educators (healthy eating and taking medication were used to develop standard messages and then linguistically tailored using features of the six different construct segment types of the Descriptor™. A subset of seven participants each provided feedback on their preference for standard or linguistically tailored messages; 12 comparisons between standard and tailored messages were made. Results: Overall, the tailored messages were preferred to the standard messages. When the messages were matched to specific construct segment types, the tailored messages were preferred over the standard messages, although this was not statistically significant. Conclusion: Linguistically tailoring messages based on construct segments is feasible. Furthermore, tailored messages were more often preferred over standard messages. This study provides some preliminary evidence for tailoring messages based on the linguistic features of control orientation, agency, and affect

  6. Incidence and impact of pain conditions and comorbid illnesses

    Directory of Open Access Journals (Sweden)

    Davis JA

    2011-10-01

    Full Text Available Jessica A Davis, Rebecca L Robinson, Trong Kim Le, Jin XieLilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USABackground: Individuals with pain often present with more than one painful condition. The purpose of this study was to characterize the rates of comorbidity, pain medication use, and health care costs for 23 selected pain conditions in a large health plan using administrative claims data from 2005 to 2007.Methods: Eligible patients included 1,211,483 adults with at least one pain condition during the one-year study period. Pain condition cohorts were classified based on the first diagnosis present in the claims during the study period.Results: Musculoskeletal pain conditions were among the most prevalent cohorts including low back pain, osteoarthritis, and fibromyalgia. Cancer pain was the least prevalent cohort. Conditions with the lowest illness severity included migraine and painful bladder syndrome cohorts, while cohorts with diabetic neuropathy, human immunodeficiency virus (HIV-associated pain, and cancer pain were the most severe. Across cohorts, the mean number of comorbid pain conditions ranged from 1.39 (for cancer pain and migraine to 2.65 (for multiple sclerosis pain. High rates of mental health conditions were found in cohorts with HIV-associated pain and multiple sclerosis pain (42.59% and 34.78% and were lowest among cohorts with rheumatoid arthritis and psoriatic arthropathy (12.73% and 13.31%, respectively. Rates of sleep disorders ranged from 5.47% (for painful bladder syndrome to 11.59% (for multiple sclerosis pain. Overall, patients averaged 3.53 unique pain medications during the study period. Considerable annual total health care costs were observed in the cancer pain cohort and the lowest costs were observed in the postherpetic neuropathy, surgically-induced pain, migraine, and irritable bowel syndrome cohorts. Costs attributed to pain were highest among the multiple sclerosis, HIV, and cancer

  7. Bioethics in popular science: evaluating the media impact of The Immortal Life of Henrietta Lacks on the biobank debate.

    Science.gov (United States)

    Nisbet, Matthew C; Fahy, Declan

    2013-02-28

    The global expansion of biobanks has led to a range of bioethical concerns related to consent, privacy, control, ownership, and disclosure. As an opportunity to engage broader audiences on these concerns, bioethicists have welcomed the commercial success of Rebecca Skloot's 2010 bestselling book The Immortal Life of Henrietta Lacks. To assess the impact of the book on discussion within the media and popular culture more generally, we systematically analyzed the ethics-related themes emphasized in reviews and articles about the book, and in interviews and profiles of Skloot. We conducted a content analysis of a population of relevant English-language articles and transcripts (n = 125) produced by news organizations and publications in the U.S., Canada, Great Britain/Ireland, and Australia/New Zealand. We scored each article for the emphasis and appearance of 9 ethics-related themes. These were informed consent, welfare of the vulnerable, compensation, scientific progress, control/access, accountability/oversight, privacy, public education, and advocacy. The informed consent theme dominated media discussion, with almost 39.2 percent of articles/transcripts featuring the theme as a major focus and 44.8 percent emphasizing the theme as a minor focus. Other prominent themes and frames of reference focused on the welfare of the vulnerable (18.4 percent major emphasis; 36.0 percent minor emphasis), and donor compensation (19.2 percent major; 52.8 percent minor). Ethical themes that comprised a second tier of prominence included those of scientific progress, control/access, and accountability/oversight. The least prominent themes were privacy, public education, and advocacy. The book has been praised as an opportunity to elevate media discussion of bioethics, but such claims should be re-considered. The relatively narrow focus on informed consent in the media discussion generated by Skloot's book may limit the ability of ethicists and advocates to elevate attention to

  8. Dextrose gel for neonatal hypoglycaemia (the Sugar Babies Study): a randomised, double-blind, placebo-controlled trial.

    Science.gov (United States)

    Harris, Deborah L; Weston, Philip J; Signal, Matthew; Chase, J Geoffrey; Harding, Jane E

    2013-12-21

    Trust, the Health Research Council of New Zealand, and the Rebecca Roberts Scholarship. Copyright © 2013 Elsevier Ltd. All rights reserved.

  9. Outcomes associated with conventional versus lipid-based formulations of amphotericin B in propensity-matched groups

    Directory of Open Access Journals (Sweden)

    Campbell RS

    2013-10-01

    Full Text Available Rebecca S Campbell,1 Paresh Chaudhari,2 Harlen D Hays,1 Robert J Taylor,1 Brian H Nathanson,3 Samuel A Bozzette,1 David Horn4 1Cerner Research, Culver City, CA, USA; 2Astellas Scientific and Medical Affairs, Inc., Northbrook, IL, USA; 3OptiStatim, LLC, Longmeadow, MA, USA; 4David Horn LLC, Doylestown, PA, USA Background: Lipid-based formulations of amphotericin B (LF-AMB are indicated for treatment of invasive fungal infections in patients intolerant to conventional amphotericin B (CAB or with refractory infections. Physicians still may choose to administer CAB to such patients. We described the use of CAB and LF-AMB in this population and quantified differences in post-amphotericin B length of stay (LOS among survivors and hospital mortality in matched patients. Methods: Data were extracted from Health Facts (Cerner Corporation, Kansas City, MO, USA for a retrospective cohort analysis. Inpatients aged ≥18 years with evidence of fungal infection and with orders for LF-AMB or CAB on  ≥2 days from January 2001 to June 2010 were identified. Patients were required to have renal insufficiency or other relative contraindications to use of CAB, exposure to nephrotoxic agents, or evidence of a CAB-refractory infection. Multilevel (hierarchical mixed-effects logistic regression was used to determine factors associated with initial exposure to LF-AMB versus CAB. Multivariate adjustment of outcomes was done using propensity score matching. Results: 655 patients were identified: 322 patients initiated therapy with CAB and 333 initiated treatment with LF-AMB. Compared to those initiating CAB, patients initiating LF-AMB had greater acuity and underlying disease severity. In unadjusted analyses, hospital mortality was significantly higher in the LF-AMB group (32.2% versus 23.7%; P = 0.02. After propensity score matching and covariate adjustment, mortality equalized and observed differences in LOS after amphotericin B initiation decreased. Conclusion

  10. Assessing the Medication Adherence App Marketplace From the Health Professional and Consumer Vantage Points.

    Science.gov (United States)

    Dayer, Lindsey E; Shilling, Rebecca; Van Valkenburg, Madalyn; Martin, Bradley C; Gubbins, Paul O; Hadden, Kristie; Heldenbrand, Seth

    2017-04-19

    ratings are positively but weakly correlated with user-testing scores suggesting that our rating tool has some validity but that consumers and clinicians may assess adherence app quality differently. ©Lindsey E Dayer, Rebecca Shilling, Madalyn Van Valkenburg, Bradley C Martin, Paul O Gubbins, Kristie Hadden, Seth Heldenbrand. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 19.04.2017.

  11. The same teacher, the same curriculum materials, different schools: What is the enacted curriculum?

    Science.gov (United States)

    Eisenmann, Tammy

    appeared in the curriculum materials, were implemented: The students were exposed to the main mathematical subjects/ideas and the mathematical sequence that appeared in the curriculum materials; the lesson structure was similar to the recommended structure, and did not include work on assignments that were not recommended in the curriculum materials. In spite of the similarities in each of the classes, and the curriculum materials, and between the two classes -- a few differences were found, mainly while comparing the enactment in Tavor versus the recommendations in the curriculum materials and the enactment in Carmel. Examination of the algebraic types of activities that the students were exposed to in Carmel and Tavor schools throughout the school year shows that, although the students in the two schools were not required to deal with a similar number of assignments and tasks, in both schools they were exposed to the three types of algebraic activities in similar distribution as appear in the curriculum materials. The focus on the algebraic types of activities exposed to during the whole class work, shows that a significantly lesser percentage of global/meta9level activities was enacted in Tavor. In Tavor, teacher Sara omitted global/meta level activities that appear in the curriculum materials and in addition, there were several cases in which the same assignment/task was enacted in Carmel as a global/meta9level activity but was not enacted in Tavor. In case study 2, which included teacher Rebecca and schools Gamla and Arbel, not all the recommendations in the curriculum material were enacted. Indeed, in both classes the main mathematics subjects/ideas intended for this topic according to the curriculum materials were presented to the students, and the topic was taught according to the mathematical sequence that appeared in the curriculum materials, however in both classes the lesson structures were different from the intended structure -- unintended assignments were

  12. Controlling Your "App"etite: How Diet and Nutrition-Related Mobile Apps Lead to Behavior Change.

    Science.gov (United States)

    West, Joshua H; Belvedere, Lindsay M; Andreasen, Rebecca; Frandsen, Christine; Hall, P Cougar; Crookston, Benjamin T

    2017-07-10

    associated with diet-related behavior change. Theory (Pmotivation, desire, self-efficacy, attitudes, knowledge, and goal setting may be particularly useful. As the number of diet- and nutrition-related apps continues to grow, developers should consider integrating appropriate theoretical constructs for health behavior change into the newly developed mobile apps. ©Joshua H West, Lindsay M Belvedere, Rebecca Andreasen, Christine Frandsen, P Cougar Hall, Benjamin T Crookston. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 10.07.2017.

  13. Modeling Diffusion and Buoyancy-Driven Convection with Application to Geological CO2 Storage

    KAUST Repository

    Allen, Rebecca

    2015-04-01

    ABSTRACT Modeling Diffusion and Buoyancy-Driven Convection with Application to Geological CO2 Storage Rebecca Allen Geological CO2 storage is an engineering feat that has been undertaken around the world for more than two decades, thus accurate modeling of flow and transport behavior is of practical importance. Diffusive and convective transport are relevant processes for buoyancy-driven convection of CO2 into underlying fluid, a scenario that has received the attention of numerous modeling studies. While most studies focus on Darcy-scale modeling of this scenario, relatively little work exists at the pore-scale. In this work, properties evaluated at the pore-scale are used to investigate the transport behavior modeled at the Darcy-scale. We compute permeability and two different forms of tortuosity, namely hydraulic and diffusive. By generating various pore ge- ometries, we find hydraulic and diffusive tortuosity can be quantitatively different in the same pore geometry by up to a factor of ten. As such, we emphasize that these tortuosities should not be used interchangeably. We find pore geometries that are characterized by anisotropic permeability can also exhibit anisotropic diffusive tortuosity. This finding has important implications for buoyancy-driven convection modeling; when representing the geological formation with an anisotropic permeabil- ity, it is more realistic to also account for an anisotropic diffusivity. By implementing a non-dimensional model that includes both a vertically and horizontally orientated 5 Rayleigh number, we interpret our findings according to the combined effect of the anisotropy from permeability and diffusive tortuosity. In particular, we observe the Rayleigh ratio may either dampen or enhance the diffusing front, and our simulation data is used to express the time of convective onset as a function of the Rayleigh ratio. Also, we implement a lattice Boltzmann model for thermal convective flows, which we treat as an analog for

  14. eHealth Literacy and Health Behaviors Affecting Modern College Students: A Pilot Study of Issues Identified by the American College Health Association.

    Science.gov (United States)

    Britt, Rebecca Katherine; Collins, William Bart; Wilson, Kari; Linnemeier, Georgiann; Englebert, Andrew Mark

    2017-12-19

    diet. These results suggest several areas that may be targeted for future health campaigns toward college students. In addition, eHEALS was found to be a useful instrument for college students in the United States. Lastly, these results point to a need to deliver targeted information to college students, particularly since eHEALS captures literacy based on positively phrased items. ©Rebecca Katherine Britt, William Bart Collins, Kari Wilson, Georgiann Linnemeier, Andrew Mark Englebert. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 19.12.2017.

  15. Quantitative sensory testing measures individual pain responses in emergency department patients

    Directory of Open Access Journals (Sweden)

    Duffy KJ

    2017-05-01

    Full Text Available Kevin J Duffy, Katharyn L Flickinger, Jeffrey T Kristan, Melissa J Repine, Alexandro Gianforcaro, Rebecca B Hasley, Saad Feroz, Jessica M Rupp, Jumana Al-Baghli, Maria L Pacella, Brian P Suffoletto, Clifton W Callaway Department of Emergency Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA Background: Refining and individualizing treatment of acute pain in the emergency department (ED is a high priority, given that painful complaints are the most common reasons for ED visits. Few tools exist to objectively measure pain perception in the ED setting. We speculated that variation in perception of fixed painful stimuli would explain individual variation in reported pain and response to treatment among ED patients. Materials and methods: In three studies, we 1 describe performance characteristics of brief quantitative sensory testing (QST in 50 healthy volunteers, 2 test effects of 10 mg oxycodone versus placebo on QST measures in 18 healthy volunteers, and 3 measure interindividual differences in nociception and treatment responses in 198 ED patients with a painful complaint during ED treatment. QST measures adapted for use in the ED included pressure sensation threshold, pressure pain threshold (PPT, pressure pain response (PPR, and cold pain tolerance (CPT tests. Results: First, all QST measures had high inter-rater reliability and test–retest reproducibility. Second, 10 mg oxycodone reduced PPR, increased PPT, and prolonged CPT. Third, baseline PPT and PPR revealed hyperalgesia in 31 (16% ED subjects relative to healthy volunteers. In 173 (88% ED subjects who completed repeat testing 30 minutes after pain treatment, PPT increased and PPR decreased (Cohen’s dz 0.10–0.19. Verbal pain scores (0–10 for the ED complaint decreased by 2.2 (95% confidence intervals [CI]: 1.9, 2.6 (Cohen’s dz 0.97 but did not covary with the changes in PPT and PPR (r=0.05–0.13. Treatment effects were greatest in ED subjects

  16. Epidemiology of respiratory syncytial virus in children ≤2 years of age hospitalized with lower respiratory tract infections in the Russian Federation: a prospective, multicenter study

    Directory of Open Access Journals (Sweden)

    Vladimir Tatochenko

    2010-09-01

    Full Text Available Vladimir Tatochenko1, Vasily Uchaikin2, Aleksandr Gorelov3, Konstantin Gudkov4, Andrew Campbell5, Gregory Schulz5, Rebecca Prahl5, Gerard Notario51Scientific Centre of Children’s Health, Russian Academy of Medical Sciences, Lomonosovskiy Prospect, Moscow, Russia; 2Russian State Medical University of Roszdrav, Moscow, Russia; 3Central Scientific Research Institution of Epidemiology, Moscow, Russia; 4Abbott Laboratories LLC, Khimki, Moscow, Russia; 5Abbott Laboratories, Abbott Park, IL, USABackground: Respiratory syncytial virus (RSV is the leading cause of severe lower respiratory tract infections among infants and young children, and is responsible for an estimated four million deaths per year globally. A monthly injection of palivizumab has been used for prophylaxis of serious RSV infections among high-risk children in 71 countries since 1998 and approval for use in the Russian Federation was obtained in February 2010. A recommendation for RSV prophylaxis in the Russian Federation would require knowledge of the prevalence and seasonality of RSV in that country.Methods: In a prospective, multicenter, epidemiological study of the prevalence, seasonality, and peak occurrence of RSV infection, children aged ≤2 years hospitalized for lower respiratory tract infections in three regions of the Russian Federation, from September 2008 through April 2009, were screened and tested for RSV using rapid immunochromatography of nasopharyngeal lavage. For subjects who were tested positive, hospitalization data were collected.Results: Of 519 children aged ≤2 years enrolled from September 11, 2008 through April 26, 2009, 197 tested positive for RSV (38.0%, 95% CI: 33.8, 42.3. The onset of the 2008–2009 RSV season in the Russian Federation occurred in late October 2008, similar to what is observed in other northern temperate zones. Peak activity occurred in early April 2009, when 62% of children enrolled tested positive for RSV.Conclusion: The prevalence

  17. A patient and community-centered approach selecting endpoints for a randomized trial of a novel advance care planning tool

    Directory of Open Access Journals (Sweden)

    Bridges JFP

    2018-02-01

    Full Text Available John FP Bridges,1,2 Norah L Crossnohere,2 Anne L Schuster,1 Judith A Miller,3 Carolyn Pastorini,3,† Rebecca A Aslakson2,4,5 1Department of Health Policy and Management, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 2Department of Health, Behavior, and Society, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 3Patient-Centered Outcomes Research Institute (PCORI Project, Baltimore, MD, 4Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins School of Medicine, Baltimore, MD, 5Armstrong Institute for Patient Safety and Quality, The Johns Hopkins School of Medicine, Baltimore, MD, USA †Carolyn Pastorini passed away on August 24, 2015 Background: Despite a movement toward patient-centered outcomes, best practices on how to gather and refine patients’ perspectives on research endpoints are limited. Advanced care planning (ACP is inherently patient centered and would benefit from patient prioritization of endpoints for ACP-related tools and studies.Objective: This investigation sought to prioritize patient-centered endpoints for the content and evaluation of an ACP video being developed for patients undergoing major surgery. We also sought to highlight an approach using complementary engagement and research strategies to document priorities and preferences of patients and other stakeholders.Materials and methods: Endpoints identified from a previously published environmental scan were operationalized following rating by a caregiver co-investigator, refinement by a patient co-investigator, review by a stakeholder committee, and validation by patients and family members. Finalized endpoints were taken to a state fair where members of the public who indicated that they or a loved one had undergone major surgery prioritized their most relevant endpoints and provided comments.Results: Of the initial 50 ACP endpoints identified from the review, 12 endpoints were selected for public

  18. The Physiological Bases of Hidden Noise-Induced Hearing Loss: Protocol for a Functional Neuroimaging Study.

    Science.gov (United States)

    Dewey, Rebecca Susan; Hall, Deborah A; Guest, Hannah; Prendergast, Garreth; Plack, Christopher J; Francis, Susan T

    2018-03-09

    procedures for hidden hearing loss, enabling early identification of noise-induced auditory damage via the detection of changes in central auditory processing. Consequently, this will generate the opportunity to give personalized advice regarding provision of ear defense and monitoring of further damage, thus reducing the incidence of noise-induced hearing loss. ©Rebecca Susan Dewey, Deborah A Hall, Hannah Guest, Garreth Prendergast, Christopher J Plack, Susan T Francis. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 09.03.2018.

  19. Vitamin D status and hypertension: a review

    Directory of Open Access Journals (Sweden)

    Ke L

    2015-04-01

    Full Text Available Liang Ke,1 Rebecca S Mason,2 Maina Kariuki,3 Elias Mpofu,1 Kaye E Brock2 1Faculty of Health Sciences, 2Faculty of Medicine, University of Sydney, 3Biostatistical Officer Training Program, NSW Ministry of Health, Sydney, NSW, Australia Abstract: Vitamin D is a steroid prohormone synthesized in the skin following ultraviolet exposure and also achieved through supplemental or dietary intake. While there is strong evidence for its role in maintaining bone and muscle health, there has been recent debate regarding the role of vitamin D deficiency in hypertension based on conflicting epidemiological evidence. Thus, we conducted a scoping systematic literature review and meta-analysis of all observational studies published up to early 2014 in order to map trends in the evidence of this association. Mixed-effect meta-analysis was performed to pool risk estimates from ten prospective studies (n=58,262 (pooled risk for incident hypertension, relative risk [RR] =0.76 (0.63–0.90 for top vs bottom category of 25-hydroxyvitamin D [25OHD] and from 19 cross-sectional studies (n=90,535 (odds ratio [OR] =0.79 (0.73–0.87. Findings suggest that the better the assessed quality of the respective study design, the stronger the relationship between higher 25OHD levels and hypertension risk (RR =0.67 (0.51–0.88; OR =0.77 (0.72–0.89. There was significant heterogeneity among the findings for both prospective and cross-sectional studies, but no evidence of publication bias was shown. There was no increased risk of hypertension when the participants were of older age or when they were vitamin D deficient. Younger females showed strong associations between high 25OHD levels and hypertension risk, especially in prospective studies (RR =0.36 (0.18–0.72; OR =0.62 (0.44–0.87. Despite the accumulating evidence of a consistent link between vitamin D and blood pressure, these data are observational, so questions still remain in relation to the causality of this

  20. Intervention to Increase HIV Testing Among Substance-Using Young Men Who Have Sex With Men: Protocol for a Randomized Controlled Trial.

    Science.gov (United States)

    Stephenson, Rob; Bonar, Erin E; Carrico, Adam; Hunter, Alexis; Connochie, Daniel; Himmelstein, Rebecca; Bauermeister, Jose

    2018-04-30

    interviewing into HIV CTR provides an opportunity to tailor counseling services for YMSM and transgender people to address additional client barriers to HIV and STI testing. ClinicalTrials.gov NCT02945436; http://clinicaltrials.gov/ct2/show/NCT02945436 (Archived by WebCite at http://www.webcitation.org/6yFyOK57w). ©Rob Stephenson, Erin E Bonar, Adam Carrico, Alexis Hunter, Daniel Connochie, Rebecca Himmelstein, Jose Bauermeister. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 30.04.2018.

  1. Use of and Beliefs About Mobile Phone Apps for Diabetes Self-Management: Surveys of People in a Hospital Diabetes Clinic and Diabetes Health Professionals in New Zealand.

    Science.gov (United States)

    Boyle, Leah; Grainger, Rebecca; Hall, Rosemary M; Krebs, Jeremy D

    2017-06-30

    confidence in the quality and safety of diabetes management apps to people with diabetes (potential app users) and HPs (potential app prescribers). ©Leah Boyle, Rebecca Grainger, Rosemary M Hall, Jeremy D Krebs. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 30.06.2017.

  2. A systematic review of patient-reported measures of burden of treatment in three chronic diseases

    Directory of Open Access Journals (Sweden)

    Eton DT

    2013-06-01

    Full Text Available David T Eton,1 Tarig A Elraiyah,2 Kathleen J Yost,3 Jennifer L Ridgeway,1 Anna Johnson,2 Jason S Egginton,1 Rebecca J Mullan,4 Mohammad Hassan Murad,2 Patricia J Erwin,2 Victor M Montori1,2 1Division of Heath Care Policy and Research, Department of Health Sciences Research, 2Knowledge and Evaluation Research Unit, 3Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA; 4University of Minnesota Medical School, Minneapolis, MN, USA Background: Burden of treatment refers to the workload of health care and its impact on patient functioning and well-being. There are a number of patient-reported measures that assess burden of treatment in single diseases or in specific treatment contexts. A review of such measures could help identify content for a general measure of treatment burden that could be used with patients dealing with multiple chronic conditions. We reviewed the content and psychometric properties of patient-reported measures that assess aspects of treatment burden in three chronic diseases, ie, diabetes, chronic kidney disease, and heart failure. Methods: We searched Ovid MEDLINE, Ovid EMBASE, Ovid PsycINFO, and EBSCO CINAHL through November 2011. Abstracts were independently reviewed by two people, with disagreements adjudicated by a third person. Retrieved articles were reviewed to confirm relevance, with patient-reported measures scrutinized to determine consistency with the definition of burden of treatment. Descriptive information and psychometric properties were extracted. Results: A total of 5686 abstracts were identified from the database searches. After abstract review, 359 full-text articles were retrieved, of which 76 met our inclusion criteria. An additional 22 articles were identified from the references of included articles. From the 98 studies, 57 patient-reported measures of treatment burden (full measures or components within measures were identified. Most were multi-item scales

  3. PUBLISHER'S ANNOUNCEMENT: Editorial developments

    Science.gov (United States)

    2009-01-01

    that make outstanding contributions to the field and we look forward to awarding the inaugural prizes in May 2009. With the help of Murray Batchelor and our distinguished Editorial Board, we will be working to further improve the quality of the journal whilst continuing to offer excellent services to our readers, authors and referees. We hope that you benefit from reading the journal. If you have any comments or questions, please do not hesitate to contact us at jphysa@iop.org. Rebecca Gillan Publisher

  4. PUBLISHER'S ANNOUNCEMENT: Editorial developments Editorial developments

    Science.gov (United States)

    Gillan, Rebecca

    2009-01-01

    that make outstanding contributions to the field and we look forward to awarding the inaugural prizes in May 2009. With the help of Murray Batchelor and our distinguished Editorial Board, we will be working to further improve the quality of the journal whilst continuing to offer excellent services to our readers, authors and referees. We hope that you benefit from reading the journal. If you have any comments or questions, please do not hesitate to contact us at jphysa@iop.org. Rebecca Gillan Publisher

  5. Smoking and renal function in people living with human immunodeficiency virus: a Danish nationwide cohort study

    Directory of Open Access Journals (Sweden)

    Ahlström MG

    2015-08-01

    Full Text Available Magnus Glindvad Ahlström,1 Bo Feldt-Rasmussen,2 Rebecca Legarth,1 Gitte Kronborg,3 Court Pedersen,4 Carsten Schade Larsen,5 Jan Gerstoft,1 Niels Obel1 1Department of Infectious Diseases, 2Department of Nephrology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, 3Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, 4Department of Infectious Diseases, Odense University Hospital, Odense, 5Department of Infectious Diseases, Aarhus University Hospital, Skejby, Aarhus, Denmark Introduction: Smoking is a main risk factor for morbidity and mortality in people living with human immunodeficiency virus (PLHIV, but its potential association with renal impairment remains to be established. Methods: We did a nationwide population-based cohort study in Danish PLHIV to evaluate the association between smoking status and 1 overall renal function and risk of chronic kidney disease (CKD, 2 risk of any renal replacement therapy (aRRT, and 3 mortality following aRRT. We calculated estimated creatinine clearance using the Cockcroft–Gault equation (CG-CrCl, and evaluated renal function graphically. We calculated cumulative incidence of CKD (defined as two consecutive CG-CrCls of ≤60 mL/min, ≥3 months apart and aRRT and used Cox regression models to calculate incidence rate ratios (IRRs for risk of CKD, aRRT, and mortality rate ratios (MRRs following aRRT. Results: From the Danish HIV Cohort Study, we identified 1,475 never smokers, 768 previous smokers, and 2,272 current smokers. During study period, we observed no association of smoking status with overall renal function. Previous and current smoking was not associated with increased risk of CKD (adjusted IRR: 1.1, 95% confidence interval [CI]: 0.7–1.7; adjusted IRR: 1.3, 95% CI: 0.9–1.8 or aRRT (adjusted IRR: 0.8, 95% CI: 0.4–1.7; adjusted IRR: 0.9, 95% CI: 0.5–1.7. Mortality following aRRT was high in PLHIV and increased in smokers vs never smokers (adjusted MRR: 3

  6. Efficiency of spinal anesthesia versus general anesthesia for lumbar spinal surgery: a retrospective analysis of 544 patients

    Directory of Open Access Journals (Sweden)

    Pierce JT

    2017-10-01

    Full Text Available John T Pierce,1 Guy Kositratna,2 Mark A Attiah,1 Michael J Kallan,3 Rebecca Koenigsberg,1 Peter Syre,1 David Wyler,4 Paul J Marcotte,1 W Andrew Kofke,1,2 William C Welch1 1Department of Neurosurgery, 2Department of Anesthesiology and Critical Care, 3Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, 4Department of Anesthesiology and Critical Care, Neurosurgery, Jefferson Hospital of Neuroscience, Thomas Jefferson University, Philadelphia PA, USA Background: Previous studies have shown varying results in selected outcomes when directly comparing spinal anesthesia to general in lumbar surgery. Some studies have shown reduced surgical time, postoperative pain, time in the postanesthesia care unit (PACU, incidence of urinary retention, postoperative nausea, and more favorable cost-effectiveness with spinal anesthesia. Despite these results, the current literature has also shown contradictory results in between-group comparisons. Materials and methods: A retrospective analysis was performed by querying the electronic medical record database for surgeries performed by a single surgeon between 2007 and 2011 using procedural codes 63030 for diskectomy and 63047 for laminectomy: 544 lumbar laminectomy and diskectomy surgeries were identified, with 183 undergoing general anesthesia and 361 undergoing spinal anesthesia (SA. Linear and multivariate regression analyses were performed to identify differences in blood loss, operative time, time from entering the operating room (OR until incision, time from bandage placement to exiting the OR, total anesthesia time, PACU time, and total hospital stay. Secondary outcomes of interest included incidence of postoperative spinal hematoma and death, incidence of paraparesis, plegia, post-dural puncture headache, and paresthesia, among the SA patients. Results: SA was associated with significantly lower operative time, blood loss, total anesthesia time, time

  7. Role of the community pharmacist in emergency contraception counseling and delivery in the United States: current trends and future prospects

    Directory of Open Access Journals (Sweden)

    Rafie S

    2017-03-01

    Full Text Available Sally Rafie,1 Rebecca H Stone,2 Tracey A Wilkinson,3 Laura M Borgelt,4,5 Shareen Y El-Ibiary,6 Denise Ragland7 1Department of Pharmacy, UC San Diego Health, San Diego, CA, 2Department of Clinical and Administrative Pharmacy, University of Georgia, College of Pharmacy, Athens, GA, 3Children’s Health Services Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, 4Department of Clinical Pharmacy, 5Department of Family Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO, 6Department of Pharmacy Practice, College of Pharmacy, Midwestern University, Glendale, AZ, 7Department of Pharmacy Practice, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR, USA Abstract: Women and couples continue to experience unintended pregnancies at high rates. In the US, 45% of all pregnancies are either mistimed or unwanted. Mishaps with contraceptives, such as condom breakage, missed pills, incorrect timing of patch or vaginal ring application, contraceptive nonuse, forced intercourse, and other circumstances, place women at risk of unintended pregnancy. There is a critical role for emergency contraception (EC in preventing those pregnancies. There are currently three methods of EC available in the US. Levonorgestrel EC pills have been available with a prescription for over 15 years and over-the-counter since 2013. In 2010, ulipristal acetate EC pills became available with a prescription. Finally, the copper intrauterine device remains the most effective form of EC. Use of EC is increasing over time, due to wider availability and accessibility of EC methods. One strategy to expand access for both prescription and nonprescription EC products is to include pharmacies as a point of access and allow pharmacist prescribing. In eight states, pharmacists are able to prescribe and provide EC directly to women: levonorgestrel EC in eight states and ulipristal

  8. Effectiveness of an Internet- and App-Based Intervention for College Students With Elevated Stress: Randomized Controlled Trial.

    Science.gov (United States)

    Harrer, Mathias; Adam, Sophia Helen; Fleischmann, Rebecca Jessica; Baumeister, Harald; Auerbach, Randy; Bruffaerts, Ronny; Cuijpers, Pim; Kessler, Ronald C; Berking, Matthias; Lehr, Dirk; Ebert, David Daniel

    2018-04-23

    depression. Internet- and mobile-based interventions could be an effective and cost-effective approach to reduce consequences of college-related stress and might potentially attract students with clinically relevant depression who would not otherwise seek help. German Clinical Trial Register DRKS00010212; http://www.drks.de/drks_web/navigate.do? navigationId=trial.HTML&TRIAL_ID=DRKS00010212 (Archived by WebCite at http://www.webcitation.org/6w55Ewhjd). ©Mathias Harrer, Sophia Helen Adam, Rebecca Jessica Fleischmann, Harald Baumeister, Randy Auerbach, Ronny Bruffaerts, Pim Cuijpers, Ronald C Kessler, Matthias Berking, Dirk Lehr, David Daniel Ebert. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 23.04.2018.

  9. Barriers and facilitators associated with colonoscopy completion in individuals with multiple chronic conditions: a qualitative study

    Directory of Open Access Journals (Sweden)

    Sultan S

    2017-05-01

    Full Text Available Shahnaz Sultan,1–4 Melissa R Partin,1,2 Phalgoon Shah,5 Jennifer LeLaurin,4 Ivette Magaly Freytes,4 Chandylen L Nightingale,6 Susan F Fesperman,4 Barbara A Curbow,7 Rebecca J Beyth3,4,8 1Center for Chronic Disease Outcomes Research, Minneapolis Veterans Affairs Health Care System, 2Department of Medicine, University of Minnesota, Minneapolis, MN, 3Department of Medicine, University of Florida College of Medicine, Gainesville, FL, 4Center of Innovation on Disability and Rehabilitation Research, North Florida/South Georgia Veterans Health System, Gainesville, FL, 5Department of Medicine, Tripler Army Medical Center, Honolulu, HI, 6Department of Social Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem NC, 7Department of Community and Behavioral Health, University of Maryland, College Park, MD, 8Geriatric Research, Education and Clinical Center, North Florida/South Georgia Veterans Health System, Gainesville, FL, USA Background: A recommendation to undergo a colonoscopy, an invasive procedure that requires commitment and motivation, planning (scheduling and finding a driver and preparation (diet restriction and laxative consumption, may be uniquely challenging for individuals with multiple chronic conditions (MCCs. This qualitative study aimed to describe the barriers and facilitators to colonoscopy experienced by such patients.Materials and methods: Semistructured focus groups were conducted with male Veterans who were scheduled for outpatient colonoscopy and either failed to complete the procedure or completed the examination. Focus group recordings were transcribed and analyzed by an inductive grounded approach using constant comparative analysis.Results: Forty-four individuals aged 51–83 years participated in this study (23 adherent and 21 nonadherent. Participants had an average of 7.4 chronic conditions (range 2–14. The five most common chronic conditions were hypertension (75%, hyperlipidemia (75

  10. A randomized direct comparison of the pharmacokinetics and pharmacodynamics of apixaban and rivaroxaban

    Directory of Open Access Journals (Sweden)

    Frost C

    2014-11-01

    Full Text Available Charles Frost,1 Yan Song,1 Yu Chen Barrett,1 Jessie Wang,2 Janice Pursley,3 Rebecca A Boyd,4 Frank LaCreta1 1Exploratory Clinical and Translational Research, 2Exploratory Development Global Biometric Sciences, 3Analytical and Bioanalytical Development, Bristol-Myers Squibb Company, Princeton, NJ, USA; 4Global Innovative Pharma Business Clinical Pharmacology, Pfizer Inc., Groton, CT, USA Background: Currently, there are no direct comparisons of apixaban and rivaroxaban, two new oral direct factor Xa inhibitors approved for management of thromboembolic disorders. Objective: Compare the pharmacokinetics and anti-factor Xa activity (AXA of apixaban and rivaroxaban. Methods: In this randomized, open-label, two-period, two-treatment crossover study, healthy subjects (N=14 received apixaban 2.5 mg twice daily (BID and rivaroxaban 10 mg once daily (QD for 4 days with a ≥4.5-day washout. Plasma samples were obtained for pharmacokinetic and AXA assessments; parameters were calculated using noncompartmental methods. Results: Median time-to-maximum concentration was 2 hours for both compounds, and the mean half-life was 8.7 and 7.9 hours for apixaban and rivaroxaban, respectively. Daily exposure, the area under the curve (AUC(0–24, appeared similar for rivaroxaban (1,094 ng · h/mL and apixaban (935 ng · h/mL, whereas mean peak-to-trough plasma concentration ratio was 3.6-fold greater for rivaroxaban (16.9 than apixaban (4.7. Coefficient of variation for exposure parameters (AUC0–24, Cmax, Cmin was 20%–24% for apixaban versus 29%–46% for rivaroxaban. Peak AXA, AXA AUC(0–24, and AXA fluctuation were ~2.5-, 1.3-, and 3.5-fold higher for rivaroxaban than apixaban, respectively. Trough concentrations and AXA were lower for rivaroxaban (10 ng/mL and 0.17 IU/mL vs 17 ng/mL and 0.24 IU/mL for apixaban, respectively. Rivaroxaban exhibited a steeper concentration–AXA response (slope: 0.0172 IU/ng vs 0.0134 IU/ng for apixaban, P<0.0001. Conclusion

  11. Enhancing Survivorship Care Planning for Patients With Localized Prostate Cancer Using a Couple-Focused mHealth Symptom Self-Management Program: Protocol for a Feasibility Study.

    Science.gov (United States)

    Song, Lixin; Dunlap, Kaitlyn L; Tan, Xianming; Chen, Ronald C; Nielsen, Matthew E; Rabenberg, Rebecca L; Asafu-Adjei, Josephine K; Koontz, Bridget F; Birken, Sarah A; Northouse, Laurel L; Mayer, Deborah K

    2018-02-26

    care services between T1 and T2. We will assess the primary and secondary outcomes using measurements with sound psychometrical properties. We will use a qualitative and quantitative mixed methods approach to achieve the research aims. This project is ongoing and will be completed by the end of 2018. The results from this study will help design a definitive randomized trial to test the efficacy of the ESCPs, a potentially scalable program, to enhance supportive care for prostate cancer patients and their families. ©Lixin Song, Kaitlyn L Dunlap, Xianming Tan, Ronald C Chen, Matthew E Nielsen, Rebecca L Rabenberg, Josephine K Asafu-Adjei, Bridget F Koontz, Sarah A Birken, Laurel L Northouse, Deborah K Mayer. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 26.02.2018.

  12. Assessing Therapist Competence: Development of a Performance-Based Measure and Its Comparison With a Web-Based Measure.

    Science.gov (United States)

    Cooper, Zafra; Doll, Helen; Bailey-Straebler, Suzanne; Bohn, Kristin; de Vries, Dian; Murphy, Rebecca; O'Connor, Marianne E; Fairburn, Christopher G

    2017-10-31

    also sensitive to change, with scores being significantly higher after training than before as might be expected (mean difference 0.758, PWeb-based measure efficiently predicted therapist competence, as judged by the role-play measure (with the Web-based measure having a positive predictive value of 77% and specificity of 78%). The results of this study suggest that while it was feasible and acceptable to assess performance using the newly developed role-play measure, the highly scalable Web-based measure could be used in certain circumstances as a substitute for the more labor-intensive, and hence, more costly role-play method. ©Zafra Cooper, Helen Doll, Suzanne Bailey-Straebler, Kristin Bohn, Dian de Vries, Rebecca Murphy, Marianne E O'Connor, Christopher G Fairburn. Originally published in JMIR Mental Health (http://mental.jmir.org), 31.10.2017.

  13. Microencapsulation as a novel delivery method for the potential antidiabetic drug, Probucol

    Directory of Open Access Journals (Sweden)

    Mooranian A

    2014-09-01

    Full Text Available Armin Mooranian,1 Rebecca Negrulj,1 Nigel Chen-Tan,2 Hesham S Al-Sallami,3 Zhongxiang Fang,4 TK Mukkur,5 Momir Mikov,6,7 Svetlana Golocorbin-Kon,6,7 Marc Fakhoury,8 Gerald F Watts,9 Vance Matthews,10 Frank Arfuso,5 Hani Al-Salami1 1Biotechnology and Drug Development Research Laboratory School of Pharmacy, Curtin Health Innovation Research Institute, Biosciences Research Precinct, Curtin University, Perth, Western Australia, Australia; 2Faculty of Science and Engineering, Curtin University, Perth, Western Australia, Australia; 3School of Pharmacy, University of Otago, Dunedin, New Zealand; 4School of Public Health, Curtin University, Perth, Western Australia, Australia; 5Curtin Health Innovation Research Institute, Biosciences Research Precinct, School of Biomedical Science, Curtin University, Perth, Western Australia, Australia; 6Department of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine, University of Novi Sad, Serbia; 7Department of Pharmacy, Faculty of Medicine, University of Novi Sad, Serbia; 8Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada; 9School of Medicine and Pharmacology, Royal Perth Hospital, University of Western Australia; 10Laboratory for Metabolic Dysfunction, UWA Centre for Medical Research, Harry Perkins Institute of Medical Research, Perth, Western Australia, Australia Introduction: In previous studies, we successfully designed complex multicompartmental microcapsules as a platform for the oral targeted delivery of lipophilic drugs in type 2 diabetes (T2D. Probucol (PB is an antihyperlipidemic and antioxidant drug with the potential to show benefits in T2D. We aimed to create a novel microencapsulated formulation of PB and to examine the shape, size, and chemical, thermal, and rheological properties of these microcapsules in vitro. Method: Microencapsulation was carried out using the Büchi-based microencapsulating system developed in our laboratory. Using the polymer, sodium

  14. Sharing Annotated Audio Recordings of Clinic Visits With Patients-Development of the Open Recording Automated Logging System (ORALS): Study Protocol.

    Science.gov (United States)

    Barr, Paul J; Dannenberg, Michelle D; Ganoe, Craig H; Haslett, William; Faill, Rebecca; Hassanpour, Saeed; Das, Amar; Arend, Roger; Masel, Meredith C; Piper, Sheryl; Reicher, Haley; Ryan, James; Elwyn, Glyn

    2017-07-06

    US-wide network of primary care practices (www.iorahealth.com), has indicated a willingness to implement ORALS on a larger scale upon completion of this development project. Upon the completion of this project we will have developed a novel recording system that will be ready for large-scale testing. Our long-term goal is for ORALS to seamlessly fit into a clinic's and patient's daily routine, increasing levels of patient engagement and transparency of care. ©Paul J Barr, Michelle D Dannenberg, Craig H Ganoe, William Haslett, Rebecca Faill, Saeed Hassanpour, Amar Das, Roger Arend, Meredith C Masel, Sheryl Piper, Haley Reicher, James Ryan, Glyn Elwyn. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 06.07.2017.

  15. Acceptability, Use, and Safety of a Mobile Phone App (BlueIce) for Young People Who Self-Harm: Qualitative Study of Service Users' Experience.

    Science.gov (United States)

    Grist, Rebecca; Porter, Joanna; Stallard, Paul

    2018-02-23

    their moods and offering new strategies to manage their thoughts to self-harm. No adverse effects were reported. For those who did not find BlueIce helpful, issues around motivation to stop self-harming impeded their ability to use the app. BlueIce was judged to be a helpful and safe way of supporting adolescents to manage thoughts of self-harming. Adolescents reported numerous benefits of using BlueIce, and all would recommend the app to other young people who were struggling with self-harm. These preliminary findings are encouraging and provide initial support for the acceptability of BlueIce as a self-help intervention used in conjunction with the traditional face-to-face therapy. ©Rebecca Grist, Joanna Porter, Paul Stallard. Originally published in JMIR Mental Health (http://mental.jmir.org), 23.02.2018.

  16. Empowerment in people with COPD

    Directory of Open Access Journals (Sweden)

    Disler RT

    2015-12-01

    Full Text Available Rebecca T Disler,1–3 Jessica Appleton,1 Tracy A Smith,4,5 Matthew Hodson,6 Sally C Inglis,1,2 DorAnne Donesky,7 Patricia M Davidson8 1Faculty of Health, University of Technology Sydney, 2Centre for Cardiovascular and Chronic Care, Faculty of Health, University of Technology Sydney, 3Improving Palliative Care through Clinical Trials (ImPACCT, Sydney, 4Department of Respiratory and Sleep Medicine, Westmead Hospital, Westmead, 5Faculty of Medicine, University of NSW, Sydney, NSW, Australia; 6ACERS, Integrated Medicine and Rehabilitation Services Division, Homerton University Hospital NHS Foundation Trust, London, UK; 7Department of Physiological Nursing, UCSF School of Nursing, San Francisco, CA, 8School of Nursing, Johns Hopkins University, Baltimore, MD, USA Background: Patient empowerment is recognized as an important aspect of chronic disease management. There is an increasing expectation that health providers engage patients as active participants in their own self-management. This engagement is crucial to the chronic care model as patients with COPD and their families manage the majority of the care in the community. Understanding what influences empowerment will help health care professionals to better engage in collaborative care planning and decision making that meet the needs of this new generation of health consumers. Aim: The aim of the present study was to identify interventions or approaches that empower patients in the management of COPD. Methods: An integrative review was undertaken following the preferred reporting items for systematic reviews and meta-analyses approach. Papers were included if they 1 provided a definition or conceptualization of empowerment, and 2 reported interventions or approaches fostering empowerment in patients with COPD. Thematic analysis was used to develop conceptual themes on patient empowerment in COPD. These conceptual themes were validated by a panel of specialists in COPD, chronic disease

  17. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2008-12-01

    Full Text Available David Scott; Conscripts of Modernity: The Tragedy of Colonial Enlightenment (Shalina Puri Rebecca J. Scott; Degrees of Freedom: Louisiana and Cuba after Slavery (Olivia Maria Gomes da Cunha Patrick Bellegarde-Smith (ed.; Fragments of Bone: Neo-African Religions in a New World (Dianne M. Stewart Londa Schiebinger; Plants and Empire: Colonial Bioprospecting in the Atlantic World (J.D. La Fleur F. Abiola Irele, Simon Gikandi (eds.;The Cambridge History of African and Caribbean Literature (A. James Arnold Sean X. Goudie; Creole America: The West Indies and the Formation of Literature and Culture in the New Republic (J. Bradford Anderson Doris Garraway; The Libertine Colony: Creolization in the Early French Caribbean (Charles Forsdick Adélékè Adéèkó; The Slave’s Rebellion: Fiction, History, Orature (Owen Robinson J. Brooks Bouson; Jamaica Kincaid: Writing Memory, Writing Back to the Mother (Lizabeth Paravisini-Gebert Gary Wilder; The French Imperial Nation-State: Negritude and Colonial Humanism between the Two World Wars (Nick Nesbitt Fernando Picó; History of Puerto Rico: A Panorama of its People (Francisco A. Scarano Peter E. Siegel (ed.; Ancient Borinquen: Archaeology and Ethnohistory of Native Puerto Rico (William F. Keegan Magali Roy-Féquière; Women, Creole Identity, and Intellectual Life in Early Twentieth-Century Puerto Rico (Yolanda Martínez-San Miguel Katherine E. Browne; Creole Economics: Caribbean Cunning under the French Flag (David Beriss Louis A. Pérez, Jr; To Die in Cuba: Suicide and Society (Matt D. Childs John Lawrence Tone; War and Genocide in Cuba, 1895-1898 (Gillian McGillivray Frank Argote-Freyre; Fulgencio Batista: From Revolutionary to Strongman (Javier Figueroa-De Cárdenas Juanita de Barros, Audra Diptee, David V. Trotman (eds.; Beyond Fragmentation: Perspectives on Caribbean History (Bernard Moitt Matthew Mulcahy; Hurricanes and Society in the British Greater

  18. IntelliCare: An Eclectic, Skills-Based App Suite for the Treatment of Depression and Anxiety.

    Science.gov (United States)

    Mohr, David C; Tomasino, Kathryn Noth; Lattie, Emily G; Palac, Hannah L; Kwasny, Mary J; Weingardt, Kenneth; Karr, Chris J; Kaiser, Susan M; Rossom, Rebecca C; Bardsley, Leland R; Caccamo, Lauren; Stiles-Shields, Colleen; Schueller, Stephen M

    2017-01-05

    briefly to reduce symptoms of depression and anxiety. The IntelliCare system is elemental, allowing individual apps to be used or not used based on their effectiveness and utility, and it is eclectic, viewing treatment strategies as elements that can be applied as needed rather than adhering to a singular, overarching, theoretical model. Clinicaltrials.gov NCT02176226; http://clinicaltrials.gov/ct2/show/NCT02176226 (Archived by WebCite at http://www.webcitation/6mQZuBGk1). ©David C Mohr, Kathryn Noth Tomasino, Emily G. Lattie, Hannah L Palac, Mary J Kwasny, Kenneth Weingardt, Chris J Karr, Susan M Kaiser, Rebecca C Rossom, Leland R Bardsley, Lauren Caccamo, Colleen Stiles-Shields, Stephen M Schueller. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 05.01.2017.

  19. Targeting improved patient outcomes using innovative product listing agreements: a survey of Canadian and international key opinion leaders

    Directory of Open Access Journals (Sweden)

    Thompson M

    2016-08-01

    Full Text Available Melissa Thompson,1 Chris Henshall,2 Louis P Garrison,3 Adrian D Griffin,4 Doug Coyle,2,5 Stephen Long,6 Zayna A Khayat,7 Dana L Anger,1 Rebecca Yu8 1Cornerstone Research Group Inc., Burlington, ON, Canada; 2Health Economics Research Group, Brunel University London, London UK; 3Pharmaceutical Outcomes Research and Policy Program, School of Pharmacy, University of Washington, Seattle, WA, USA; 4Government Affairs & Policy, Johnson & Johnson, High Wycombe, UK; 5School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa, Ottawa, ON, Canada; 6Health and Life Sciences, Global Public Affairs, Calgary, AB, 7Health Systems Innovation at MaRS Discovery District, Toronto, ON, Canada; 8Strategic Health Technology Assessment, Government Affairs & Market Access, Janssen Inc., Toronto, ON, Canada Objectives: To address the uncertainty associated with procuring pharmaceutical products, product listing agreements (PLAs are increasingly being used to support responsible funding decisions in Canada and elsewhere. These agreements typically involve financial-based rebating initiatives or, less frequently, outcome-based contracts. A qualitative survey was conducted to improve the understanding of outcome-based and more innovative PLAs (IPLAs based on input from Canadian and international key opinion leaders in the areas of drug manufacturing and reimbursement. Methods: Results from a structured literature review were used to inform survey development. Potential participants were invited via email to partake in the survey, which was conducted over phone or in person. Responses were compiled anonymously for review and reporting. Results: Twenty-one individuals participated in the survey, including health technology ­assessment (HTA key opinion leaders (38%, pharmaceutical industry chief executive officers/vice presidents (29%, ex-payers (19%, and current payers/drug plan managers/HTA (14%. The participants suggested that ~80%–95% of

  20. Environmental Management Welcomes a New Face and Reinforces Its Focus on Science-Based Stewardship

    Energy Technology Data Exchange (ETDEWEB)

    Dale, Virginia H [ORNL

    2010-06-01

    ENVIRONMENTAL MANAGEMENT is pleased to announce that Rebecca Efroymson will join Virginia Dale as Co-Editors-in-Chief of the journal. Dr. Efroymson brings extensive expertise in risk assessment and environmental toxicology. Her work has focused on land management, natural resources, water quality, and rare species, with recent work on benefits and risks of energy alternatives. ENVIRONMENTAL MANAGEMENT has been publishing research on the management and conservation of natural resources and habitats since 1976. Articles discuss implications for an international audience and examine a scientific or management hypothesis. As a premier scientific journal in applied and cross-cutting areas, articles come from a variety of disciplines including biology, botany, climatology, earth sciences, ecology, ecological economics, environmental engineering, fisheries, forest sciences, geography, information science, law, management science, politics, public affairs, social sciences, and zoology, most often in combinations determined by the interdisciplinary topic of the study. The journal strives to improve cross-disciplinary communication by making ideas and results available to environmental practitioners from other backgrounds. The goal of ENVIRONMENTAL MANAGEMENT is to present a wide spectrum of viewpoints and approaches, and to this end the journal consists of four main sections. Forum contains addresses, editorials, comments, and opinions about environmental matters. Articles in the Profile section describe and evaluate particular case histories, events, policies, problems, or organizations and their work. Papers in the Research section present the methods and findings from empirical and model-based scientific studies. The section on Environmental Assessment is for articles that cover methods of appraisal, measurement, and comparison. Generally, the debates published in the journal's Forum help construct better environmental research or policies; Research and Assessment

  1. Validating Experimental Bedform Dynamics on Cohesive Sand-Mud Beds in the Dee Estuary

    Science.gov (United States)

    Baas, Jaco H.; Baker, Megan; Hope, Julie; Malarkey, Jonathan; Rocha, Renata

    2014-05-01

    bed was increased. The same result was obtained for xanthan gum, which is a proxy for biological polymers produced by microphytobenthos. Yet, the xanthan gum was several orders more effective in slowing down ripple development than kaolin clay, suggesting that the cohesive forces for biological polymers are much higher than for clay minerals, and that sedimentological process models should refocus on biostabilisation processes. The first results of the field experiments show that the winnowing of fines from developing ripples and the slowing down of current ripple development in mixed cohesive sediment is mimicked on intertidal flats in the Dee estuary. In particular, these field data revealed that current ripples in cohesive sediment are smaller with more two-dimensional crestlines than in non-cohesive sand. The wider implications of these findings will be discussed. COHBED Project Team (NERC): Alan Davies (Bangor University); Daniel Parsons, Leiping Ye (University of Hull); Jeffrey Peakall (University of Leeds); Dougal Lichtman, Louise O'Boyle, Peter Thorne (NOC Liverpool); Sarah Bass, Andrew Manning, Robert Schindler (University of Plymouth); Rebecca Aspden, Emma Defew, Julie Hope, David Paterson (University of St Andrews)

  2. Effect of a Website That Presents Patients' Experiences on Self-Efficacy and Patient Competence of Colorectal Cancer Patients: Web-Based Randomized Controlled Trial.

    Science.gov (United States)

    Giesler, Jürgen M; Keller, Bettina; Repke, Tim; Leonhart, Rainer; Weis, Joachim; Muckelbauer, Rebecca; Rieckmann, Nina; Müller-Nordhorn, Jacqueline; Lucius-Hoene, Gabriele; Holmberg, Christine

    2017-10-13

    krankheitserfahrungen.de. No intervention effects were found at 2 and 6 weeks after baseline. The results of this study do not support the hypothesis that the website studied may increase self-efficacy for coping with cancer or patient competencies such as self-regulation or managing emotional distress. Possible explanations may involve characteristics of the website itself, its use by participants, or methodological reasons. Future studies aimed at evaluating potential effects of websites providing patient experiences on the basis of methodological principles such as those of DIPEx might profit from extending the range of outcome measures, from including additional measures of website usage behavior and users' motivation, and from expanding concepts, such as patient competency to include items that more directly reflect patients' perceived effects of using such a website. Clinicaltrials.gov NCT02157454; https://clinicaltrials.gov/ct2/show/NCT02157454 (Archived by WebCite at http://www.webcitation.org/6syrvwXxi). ©Jürgen M Giesler, Bettina Keller, Tim Repke, Rainer Leonhart, Joachim Weis, Rebecca Muckelbauer, Nina Rieckmann, Jacqueline Müller-Nordhorn, Gabriele Lucius-Hoene, Christine Holmberg. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 13.10.2017.

  3. Pregnant Women's Perceptions of the Risks and Benefits of Disclosure During Web-Based Mental Health E-Screening Versus Paper-Based Screening: Randomized Controlled Trial.

    Science.gov (United States)

    Kingston, Dawn; Biringer, Anne; Veldhuyzen van Zanten, Sander; Giallo, Rebecca; McDonald, Sarah; MacQueen, Glenda; Vermeyden, Lydia; Austin, Marie-Paule

    2017-10-20

    vulnerable during mental health screening. We found that women of low income, those treated previously for depression or anxiety, and those pregnant with their first child were more likely to perceive greater risk. However, these associations were very small. Pregnant women in both the e-screening and paper-based screening groups perceived benefit and risk of disclosure similarly, suggesting that providers can implement the mode of screening that is most ideal for their clinical setting. Regardless of the mode of screening, a substantial number of women reported feeling vulnerable during mental health screening, highlighting the importance of the need to reduce women's vulnerability throughout the screening process with strategies such as addressing women's concerns, explaining the rationale for screening, and discussing how results will be used. Clinicaltrials.gov NCT01899534; https://clinicaltrials.gov/ct2/show/NCT01899534 (Archived by WebCite at http://www.webcitation.org/6tRKtGC4M). ©Dawn Kingston, Anne Biringer, Sander Veldhuyzen van Zanten, Rebecca Giallo, Sarah McDonald, Glenda MacQueen, Lydia Vermeyden, Marie-Paule Austin. Originally published in JMIR Mental Health (http://mental.jmir.org), 20.10.2017.

  4. Virtual Versus In-Person Focus Groups: Comparison of Costs, Recruitment, and Participant Logistics.

    Science.gov (United States)

    Rupert, Douglas J; Poehlman, Jon A; Hayes, Jennifer J; Ray, Sarah E; Moultrie, Rebecca R

    2017-03-22

    with significant clustering around major metropolitan areas) and more likely to be non-white, less educated, and less healthy. Internet usage was higher among virtual group participants, yet virtual groups still reached light Internet users. In terms of burden, chat groups were easiest to join and required the least preparation (chat = 13 minutes, video = 40 minutes, in-person = 78 minutes). Virtual group participants joined using laptop or desktop computers, and most virtual participants (82% [9/11] chat vs 62% [8/13] video) reported having no other people in their immediate vicinity. Virtual focus groups offer potential advantages for participant diversity and reaching less healthy populations. However, virtual groups do not appear to cost less or recruit participants faster than in-person groups. Further research on virtual group data quality and group dynamics is needed to fully understand their advantages and limitations. ©Douglas J Rupert, Jon A Poehlman, Jennifer J Hayes, Sarah E Ray, Rebecca R Moultrie. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 22.03.2017.

  5. Editorial

    Directory of Open Access Journals (Sweden)

    The Editors

    2014-06-01

    Full Text Available Retention and persistence are at the forefront of attention by students, parents, and state and federal lawmakers.  We continue several decades of increasing education costs and the perception of steadily decreasing returns on investment of time and money required to achieve a higher education credential. Thus, a special issue devoted to retention is timely.  Included in this special issue of the Higher Learning Research Communications journal are a number of thought pieces and literature reviews that represent diverse perspectives on retention. Dr. Watson Scott Swail provides a provocative essay, A Different Viewpoint on Retention, in which he challenges readers to reflect on the key issues regarding retention of students. While he provides compelling statistics on the growing costs of getting a college degree, he reminds us that the core issue is one of student preparation. Dr. Swail also encourages institutions to determine what success means in its own context, through statistical analysis of predictors of retention and persistence whose results can be socialized at all who support students at the institution. Dr. Gary Burkholder and Nicole Holland provide an international perspective on retention and persistence. Through introductory analysis of the state of retention and persistence research in areas outside the United States, they encourage readers to think about retention more globally.  The authors ask the readers to consider how what we have learned about higher education, as well as retention and persistence, in the United States, can help researchers and practitioners to address higher education concerns in more meaningful and helpful ways. Dr. Rebecca Jobe and Jim Lenio then provide insight on retention and persistence research across student and institutional types as well as across educational sectors.  The authors convincingly suggest that retention is a concern that should provide a common ground for all institutions

  6. Integrated Care in Prostate Cancer (ICARE-P): Nonrandomized Controlled Feasibility Study of Online Holistic Needs Assessment, Linking the Patient and the Health Care Team.

    Science.gov (United States)

    Nanton, Veronica; Appleton, Rebecca; Dale, Jeremy; Roscoe, Julia; Hamborg, Thomas; Ahmedzai, Sam H; Arvanitis, Theodoros N; Badger, Douglas; James, Nicholas; Mendelsohn, Richard; Khan, Omar; Parashar, Deepak; Patel, Prashant

    2017-07-28

    clinical teams. Recruitment to the second phase of the study, the feasibility trial, commenced March 2017. To our knowledge, this study is the first in the United Kingdom to trial an online holistic needs assessment for men with prostate cancer, with data shared between patients and primary and secondary care providers. This study addresses recommendations in recent policy documents promoting the importance of data sharing and enhanced communication between care providers as a basis for care integration. We anticipate that this model of care will ultimately provide important benefits for both patients and the National Health Service. International Standard Randomized Controlled Trial Number (ISRCTN): 31380482; http://www.isrctn.com/ISRCTN31380482 (Archived by WebCite at http://www.webcitation.org/6s8I42u5N). ©Veronica Nanton, Rebecca Appleton, Jeremy Dale, Julia Roscoe, Thomas Hamborg, Sam H Ahmedzai, Theodoros N Arvanitis, Douglas Badger, Nicholas James, Richard Mendelsohn, Omar Khan, Deepak Parashar, Prashant Patel. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 28.07.2017.

  7. Personalized Information Service for Clinicians: Users Like It. A Review of: Jerome, Rebecca N., Nunzia Bettinsoli Giuse, S. Trent Rosenbloom, and Patrick G. Arbogast. “Exploring Clinician Adoption of a Novel Evidence Request Feature in an Electronic Medical Record System.” Journal of the Medical Library Association 96.1 (Jan. 2008: 34-41, with online appendices.

    Directory of Open Access Journals (Sweden)

    Gale G. Hannigan

    2008-09-01

    Full Text Available Objective – To examine physician use of an Evidence-Based Medicine (EBM literature request service available to clinicians through the institution’s electronic medical record system (EMR. Specifically, the authors posed the following questions: 1 Did newly implemented marketing and communication strategies increase physicians’ use of the service? 2 How did clinicians rate the relevance of the information provided? 3 How was the information provided used and shared? Design – Ten-month, prospective, observational study employing a questionnaire, statistics, a focus group, and a “before and after marketing intervention” analysis.Setting – Adult primary care outpatient clinic in an academic medical centre.Subjects – Forty-eight attending and 89 resident physicians.Methods – In 2003, a new service was introduced that allowed physicians in the Adult Primary Care Center clinic to request evidence summaries from the library regarding complex clinical questions. Contact with the library was through the secure messaging feature of the institution’s electronic medical record (EMR. From March through July 2005, the librarian employed “standard” publicity methods (email, flyers, posters, demonstrations to promote the service. A focus group in July 2005 provided feedback about the service as well as recommendations about communicating its availability and utility. New communication methods were implemented, including a monthly electronic “current awareness” newsletter, more frequent visits by the librarian during resident clinic hours, and collaborations between the librarian and residents preparing for morning report presentations. At the end of the study period, a 25-item Web-based questionnaire was sent to the 137 physicians with access to the service. Main Results – During the 10-month study period, 23 unique users submitted a total of 45 questions to the EBM Literature RequestService. More questions were from attending physicians than residents: 36 (80% vs. 9 (20%. At least one of the 23 users asked 12 (26% of the questions. Utilization did not significantly change after the mid-study intervention. At the end of the study, 48 physicians (35% completed the survey (32 attending physicians and 16residents. While 94% of the respondents indicated awareness of the service, only 40% indicated using it. The 19 who used the service, on average, agreed that the information provided was relevant and“sometimes leads to a change in my clinical practice” (p.37. Those who indicated that they shared the information (n=15 mostly did so with other attending physicians and residents, but also mentioned sharing with fellows, patients, and nurses. Information was typically shared verbally but also by distributing a printout, forwarding by email, and forwarding within the EMR message system. The information was used primarily for general self-education,instruction of trainees, and confirmation of a current plan.Conclusion – The newly implemented marketing and communication strategies did not significantly increase the use of the EBM Literature Request Service. Those who used the service found it relevant and often shared the information with others. Based on a small number of respondents and survey information, the librarian-provided EBM Literature Request Service was “well received”(39.

  8. Management of COPD in the UK primary-care setting: an analysis of real-life prescribing patterns

    Directory of Open Access Journals (Sweden)

    Price D

    2014-08-01

    Full Text Available David Price,1 Daniel West,2 Guy Brusselle,3–5 Kevin Gruffydd-Jones,6 Rupert Jones,7 Marc Miravitlles,8 Andrea Rossi,9 Catherine Hutton,2 Valerie L Ashton,2 Rebecca Stewart,2 Katsiaryna Bichel2 1Centre of Academic Primary Care, University of Aberdeen, Aberdeen, UK; 2Research in Real-Life Ltd, Cambridge, UK; 3Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium; 4Department of Epidemiology, 5Department of Respiratory Medicine, Erasmus Medical Center, Rotterdam, the Netherlands; 6Box Surgery, Wiltshire, UK; 7Centre for Clinical Trials and Health Research – Translational and Stratified Medicine, Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth UK; 8Department of Pneumology, Hospital Universitari Vall d'Hebron, Ciber de Enfermedades Respiratorias (CIBERES, Barcelona, Spain; 9Pulmonary Unit, Cardiovascular and Thoracic Department, University and General Hospital, Verona, Italy Background: Despite the availability of national and international guidelines, evidence suggests that chronic obstructive pulmonary disease (COPD treatment is not always prescribed according to recommendations. This study evaluated the current management of patients with COPD using a large UK primary-care database. Methods: This analysis used electronic patient records and patient-completed questionnaires from the Optimum Patient Care Research Database. Data on current management were analyzed by the Global Initiative for Chronic Obstructive Lung Disease (GOLD group and presence or absence of a concomitant asthma diagnosis, in patients with a COPD diagnosis at ≥35 years of age and with spirometry results supportive of the COPD diagnosis. Results: A total of 24,957 patients were analyzed, of whom 13,557 (54.3% had moderate airflow limitation (GOLD Stage 2 COPD. The proportion of patients not receiving pharmacologic treatment for COPD was 17.0% in the total COPD population and 17.7% in the GOLD Stage 2 subset. Approximately

  9. Burden of illness associated with painful diabetic peripheral neuropathy among adults seeking treatment in the US: results from a retrospective chart review and cross-sectional survey

    Directory of Open Access Journals (Sweden)

    Sadosky A

    2013-02-01

    Full Text Available Alesia Sadosky,1 Caroline Schaefer,2 Rachael Mann,3 Felicia Bergstrom,2 Rebecca Baik,2 Bruce Parsons,1 Srinivas Nalamachu,4 Edward Nieshoff,5 Brett R Stacey,6 Alan Anschel,7 Michael Tuchman81Pfizer Inc, New York, NY, 2Covance Market Access Services Inc, Gaithersburg, MD, 3Covance Market Access Services Inc, San Diego, CA, 4International Clinical Research Institute, Overland Park, KS, 5Rehabilitation Institute of Michigan/Wayne State University, Detroit, MI, 6Oregon Health and Science University, Portland, OR, 7Rehabilitation Institute of Chicago, Chicago, IL, 8Palm Beach Neurological Center, Palm Beach Gardens, FL, USABackground: The purpose of this study was to characterize the burden of illness among adult subjects with painful diabetic peripheral neuropathy (pDPN seeking treatment in the US.Methods: This observational study recruited 112 subjects with pDPN during routine visits from general practitioner and specialist sites. Subjects completed a one-time questionnaire, which included demographics, symptom duration, health care resource use, out-of-pocket costs, employment status, and validated measures that assessed pain, functioning, sleep, anxiety and depression, health status, and productivity. Investigators completed a case report form based on a 6-month retrospective chart review to capture clinical information, pDPN-related treatments, and other pDPN-related health care resource use over the past 6 months. Annualized costs were extrapolated based on reported 6-month health care resource use.Results: The mean age of the subjects was 61.1 years, 52.7% were female, and 17.9% were in paid employment. The most common comorbid conditions were sleep disturbance/insomnia (43.8%, depressive symptoms (41.1%, and anxiety (35.7%. The mean pain severity score was 5.2 (0–10 scale, and 79.5% reported moderate or severe pain. The mean pain interference with function score was 5.0 (0–10 scale overall, with 2.0 among mild, 5.1 among moderate, and 7

  10. Lessons From the Dot Contraceptive Efficacy Study: Analysis of the Use of Agile Development to Improve Recruitment and Enrollment for mHealth Research.

    Science.gov (United States)

    Shattuck, Dominick; Haile, Liya T; Simmons, Rebecca G

    2018-04-20

    fully automated process. Overall, 29.2% (210/719) of the participants were enrolled via a phone call, 19.9% (143/719) via chat/IM, and 50.9% (366/719) directly through the fully automated process. With respect to the demographic profile of our study sample, we found a significant statistical difference in education level across all modifications (P.05). Our findings show that agile and consistent modifications to the recruitment and enrollment process were necessary to yield an appropriate sample size. An automated process resulted in significantly higher enrollment rates than one that required phone interaction with study representatives. Although there were some differences in demographic characteristics of enrollees as the process was modified, in general, our study population is diverse and reflects the overall United States population in terms of race/ethnicity, age, and education. Additional research is proposed to identify how differences in mode of enrollment and demographic characteristics may affect participants' performance in the study. ClinicalTrials.gov NCT02833922; http://clinicaltrials.gov/ct2/show/NCT02833922 (Archived by WebCite at http://www.webcitation.org/6yj5FHrBh). ©Dominick Shattuck, Liya T Haile, Rebecca G Simmons. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 20.04.2018.

  11. Risk Profile May Affect Search Process but Not Results. A review of: McKibbon, K. Ann, Douglas B. Fridsma, and Rebecca S. Crowley. “How Primary Care Physicians’ Attitudes Toward Risk and Uncertainty Affect Their Use of Electronic Information Resources.” Journal of the Medical Library Association 95.2 (2007: 138‐46, e49‐50. 10 Nov. 2007 .

    Directory of Open Access Journals (Sweden)

    Gale G. Hannigan

    2007-12-01

    Full Text Available Objective – To compare the use, in terms of process and outcomes, of electronic information resources by primary care physicians with different risk profiles and comfort with uncertainty.Design – Survey, and observation using “think‐aloud” method.Setting – Physicians’ offices.Subjects – Canadian and U.S. primary carephysicians who report seeing patients in clinic settings.Methods – Volunteers were recruited from personal contacts and the list of physicianswho rate current studies for the McMaster Online Rating of Evidence (MORE project. Physicians completed the Pearson scale to measure attitude toward risk and the Gerrity scale to measure comfort with uncertainty, and those who scored at the extremes of each of these two scales were included in the study (n=25, resulting in four groups (risk‐seeking, risk‐avoiding, uncertainty‐stressed, uncertainty unstressed. One researcher observed each of these physicians in their offices for an hour during which they completed questionnaires about their computer skills and familiarity with resources, answered multiple‐choice clinical questions, and indicated level of certainty with regard to those answers (scale of 0 to 100%. Physicians also chose two of the clinical questions to answer using their own resources. The think‐aloud method was employed, and transcripts were coded and analyzed.Main results – The study analysis included two comparisons: risk‐seeking (11 subjects versus risk‐avoiding (11 subjects physicians,and uncertainty‐stressed (11 subjects versus uncertainty‐unstressed (10 subjects physicians. Most physicians were included in both sets of analyses. The researchers found no association of risk attitude and uncertainty stress with computer skills nor with familiarity and use of specific information resources (Internet, MEDLINE, PIER, Clinical Evidence, and UpToDate. No differences were found for the following outcomes: time spent searching, answers correct before searching, answers correct after searching, and certainty of answer if answer is right, certainty of answer if answer is wrong. There was a statistically significant association of participants’ indicating certainty for answers that were correct versus those that were not correct (pConclusion – Based on a small sample, it appears that primary care physicians who are risk‐seeking and/or less stressed by uncertainty have the same (poor search results as their more risk‐averse and stressed‐by‐uncertainty colleagues although their search processes may differ.

  12. Assessing the Efficacy of an App-Based Method of Family Planning: The Dot Study Protocol.

    Science.gov (United States)

    Simmons, Rebecca G; Shattuck, Dominick C; Jennings, Victoria H

    2017-01-18

    assess pregnancy status over time. This paper outlines the protocol for this efficacy trial, following the Standard Protocol Items: Recommendations for Intervention Trials checklist, to provide an overview of the rationale, methodology, and analysis plan. Participants will be asked to provide daily sexual history data and periodically answer surveys administered through a call center or directly on their phone. Funding for the study was provided in 2013 under the United States Agency for International Development Fertility Awareness for Community Transformation project. Recruitment for the study will begin in January of 2017. The study is expected to last approximately 18 months, depending on recruitment. Findings on the study's primary outcomes are expected to be finalized by September 2018. Reproducibility and transparency, important aspects of all research, are particularly critical in developing new approaches to research design. This protocol outlines the first study to prospectively test both the efficacy (correct use) and effectiveness (actual use) of a pregnancy prevention app. This protocol and the processes it describes reflect the dynamic integration of mobile technologies, a call center, and Health Insurance Portability and Accountability Act-compliant study procedures. Future fertility app studies can build on our approaches to develop methodologies that can contribute to the evidence base around app-based methods of contraception. ClinicalTrials.gov NCT02833922; https://clinicaltrials.gov/ct2/show/NCT02833922 (Archived be WebCite at http://www.webcitation.org/6nDkr0e76). ©Rebecca G Simmons, Dominick C Shattuck, Victoria H Jennings. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 18.01.2017.

  13. Experimenting with Educational Games using the Xbox, PC, and iPad

    Science.gov (United States)

    Rohrlick, D.; Kilb, D. L.; Peach, C. L.; Simms, E.; Yang, A.; Layman, C.; Deutscher, R.

    2012-12-01

    Daniel Rohrlick, Alan Yang, Eric Simms, Debi Kilb, Cheryl Peach, Charina Layman, Rebecca Deutscher 1. Scripps Institution of Oceanography, La Jolla, CA, USA 2. Harvard University Center for the Environment, Cambridge, MA, USA 3. Birch Aquarium at Scripps, La Jolla, CA, USA 4. The Lawrence Hall of Science, University of California Berkeley, Berkeley, CA, USA As videogames continue to grow in popularity, especially with today's youth, it is becoming clear that gaming can be a potent learning tool. But what is the best way to engage a player in learning from a videogame? Based on our five years of developing and testing our own educational games, we experimented with various forms of gaming techniques and player interaction. Our first game, "Deep-sea Extreme Environment Pilot (DEEP)", is an Xbox 360 game where players learn about deep-sea environments while controlling a Remotely Operated Vehicle (ROV). DEEP is a "traditional" videogame where players interact with a controller and a TV screen. The second game we developed for the PC is called the "Quake Catcher Network (QCN)" game. With the gameplay focused on earth sciences, players must quickly deploy seismic sensors to record aftershocks from a large earthquake. Instead of using a game controller to play the QCN game, we instead incorporate the Microsoft Kinect motion sensor for the game input. Finally, the "Glider Game" is our third and most recent game designed for use on the mobile device platform such as iPods and iPads. In this game players control ocean gliders and must complete missions while battling ocean currents, power consumption, and other unanticipated problems. Here, the gameplay is aimed toward the casual gamer using touch-screen based controls in the hope that players can easily pick up and play this game with little gaming experience. After testing our games numerous times in museums, informal science learning centers, and classrooms we have been able to track qualitatively which educational

  14. PREFACE: Wake Conference 2015

    Science.gov (United States)

    Barney, Andrew; Nørkær Sørensen, Jens; Ivanell, Stefan

    2015-06-01

    at scientists and PhD students working in the field of wake dynamics. The conference covers the following subject areas: Wake and vortex dynamics, instabilities in trailing vortices and wakes, simulation and measurements of wakes, analytical approaches for modeling wakes, wake interaction and other wind farm investigations. Many people have been involved in producing the 2015 Wake Conference proceedings. The work by the more than 60 reviewers ensuring the quality of the papers is greatly appreciated. The timely evaluation and coordination of the reviews would not have been possible without the work of the section editors: Christian Masson, ÉTS, Fernando Porté-Agel, EPFL, Gerard Schepers, ECN Wind Energy, Gijs Van Kuik, Delft University, Gunner Larsen, DTU Wind Energy, Jakob Mann, DTU Wind Energy, Javier Sanz Rodrigo, CENER, Johan Meyers, KU Leuven, Rebecca Barthelmie, Cornell University, Sandrine Aubrun-Sanches, Université d'Orléans and Thomas Leweke, IRPHE-CNRS. We are also immensely indebted to the very responsive support from the editorial team at IOP Publishing, especially Sarah Toms, during the review process of these proceedings. Visby, Sweden, June 2015 Andrew Barney, Jens Nørkær Sørensen and Stefan Ivanell Uppsala University - Campus Gotland

  15. Clinical Informatics Consult Service Positively Affects Some Clinical Decisions in the ICU. A Review of: Mulvaney, Shelagh A., Leonard Bickman, Nunzia B. Giuse, Warren E. Lambert, Nila A. Sathe, and Rebecca N. Jerome." A Randomized Effectiveness Trial of a Clinical Informatics Consult Service: Impact on Evidence-based Decision-making and Knowledge Implementation." Journal of the American Medical Informatics Association 15.2 (2008: 203-11.

    Directory of Open Access Journals (Sweden)

    Jennifer Kelson

    2009-06-01

    Full Text Available Objective – To determine whether the provision of synthesized research evidence provided by the Clinical Informatics Consult Service (CICS affects the clinical decision-making of clinicians working in intensive care units (ICUs.Design – Non-blinded randomized control effectiveness trial.Setting – ICUs in United States-based 658 bed university hospital providing tertiary care for adults and children.Subjects – Clinical staff working within one of four ICUs who submitted a request for clinical information during the study period.Methods – Valid requests submitted by clinical staff from the four clinical ICUs (medical, paediatric, trauma, or neonatal were randomly allocated to receive information from the CICS (CICS provided or no information (no CICS provided. Pre-consult forms, completed at the time of the request, examined reasons for the request and the clinical actions clinicians thought might be influenced by the search results. Requestors could opt out of the no CICS provided group either before or after the randomization of their request. Responses to requests, supplied within 0.5 to 7 days as agreed with the requestor, included a search strategy and bibliographic references, a targeted list of full-text articles, and a written synthesis and critique of the relevant research. Clinicians within both groups were free to conduct their own searches and reviews. An online evaluation form, emailed to recipients, was used to assess the impact of the information supplied. The evaluation form asked clinicians to record the time spent on their own searches, sources of information consulted including colleagues, the immediate and future impact of the information provided (either from the CICS or their own searches, what influence the information had on their clinical actions, whether there were any barriers to using the information, and quality and overall satisfaction with the results provided by the CICS. Data was analyzed according to the randomized group assignment using standard intention-to-treat analysis for the main outcomes between the two groups. Statistical adjustments were made to control for possible clustering of responses or multiple ratings from individual clinicians. The data was also analyzed on an efficacy basis depending on who provided the search results. The groups were Clinician only, CICS librarian-only, or Both Clinician and CICS librarian. Results from the Clinician only search group were used as a comparison to the remaining groups. This assessment did not take account of the randomization and therefore constitutes a cohort analysis. Results were analysed by one of two methods using statistical software SAS Proc Mixed (v9 for multi-level quantitative data analysis, e.g., analysis of variance, and SPSS (v14 for all other quantitative data analysis, including descriptive statistics.Main Results – The study period was conducted over 19 months: August 2004 to March 2006. During this time, 299 valid requests were received and 226 post consult evaluation forms were returned giving a response rate of 76%. Post consult forms were returned for 108/146 of the CICS provided group and 118/153 of the no CICS provided group. The 24% of requests that had no post consult evaluation were excluded from further analysis. Statistical tests, conducted to check for potential bias relating to missing data, suggested that the missing data had little impact on the findings.Medical and neonatal ICUs accounted for the majority of completed forms (40.3% and 38.1% respectively. The majority of opt-outs (10.2% overall were from the medical ICU. No significant difference in outcome variables was found between opt-out and other requests when tested using analysis of variance (ANOVA. Evaluation forms were completed by 89 unique clinicians and over half (49 submitted more than one request. The average requests per clinician was 2.96, SD 3.17, range 1-15, and the average number of requests per clinician who submitted more than one request was 4.57, SD 3.55, range 2-15. Total number of responses, mean, standard deviation, and Cohen’s d effect size were reported for the outcome variables based on intention to treat analysis. Results showed no significant difference between the groups on the immediate impact of the information provided, the number of articles read or the frequency with which clinicians consulted colleagues, either formally or informally. The potential future impact of the information was rated higher in the CICS group (p=Conclusion – Clinicians reported a higher level of satisfaction with search results provided by the CICS and rated the future impact of the information more highly. The CICS showed a statistically significant impact on some aspects of clinical decision-making, particularly with regard to treatment decisions. Provision of information by the CICS also appeared to encourage clinicians to undertake their own searches. However, the reasons for this are unclear.

  16. Book reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2011-12-01

    Rich Puerto Rican Citizen: History and Political Identity in Twentieth-Century New York City, by Lorrin Thomas (reviewed by Jorge Duany Livestock, Sugar and Slavery: Contested Terrain in Colonial Jamaica, by Verene A. Shepherd (reviewed by Justin Roberts Daddy Sharpe: A Narrative of the Life and Adventures of Samuel Sharpe, a West Indian Slave Written by Himself, 1832, by Fred W. Kennedy (reviewed by Gad Heuman Becoming Rasta: Origins of Rastafari Identity in Jamaica, by Charles Price (reviewed by Jahlani A. Niaah Reggaeton, edited by Raquel Z. Rivera, Wayne Marshall & Deborah Pacini Hernandez (reviewed by Alexandrine Boudreault-Fournier Carriacou String Band Serenade: Performing Identity in the Eastern Caribbean, by Rebecca S. Miller (reviewed by Nanette de Jong Caribbean Visionary: A.R.F. Webber and the Making of the Guyanese Nation, by Selwyn R. Cudjoe (reviewed by Clem Seecharan Guyana Diaries: Women’s Lives Across Difference, by Kimberely D. Nettles (reviewed by D. Alissa Trotz Writers of the Caribbean Diaspora: Shifting Homelands, Travelling Identities, edited by Jasbir Jain & Supriya Agarwal (reviewed by Joy Mahabir Queen of the Virgins: Pageantry and Black Womanhood in the Caribbean, by M. Cynthia Oliver (reviewed by Tami Navarro Notions of Identity, Diaspora, and Gender in Caribbean Women’s Writing, by Brinda Mehta (reviewed by Marie-Hélène Laforest Authority and Authorship in V.S. Naipaul, by Imraan Coovadia (reviewed by A shley Tellis Typo/Topo/Poéthique sur Frankétienne, by Jean Jonassaint (reviewed by Martin Munro Creoles in Education: An Appraisal of Current Programs and Projects, edited by Bettina Migge, Isabelle Léglise & Angela Bartens (reviewed by Jeff Siegel Material Culture in Anglo-America: Regional Identity and Urbanity in the Tidewater, Lowcountry, and Caribbean, edited by David S. Shields (reviewed by Susan Kern Tibes: People, Power, and Ritual at the Center of the Cosmos

  17. SU-A-BRA-00: Education Council Symposium: Revitalizing Your Medical Physics Classroom: Some Examples and Thoughts from the Trenches

    International Nuclear Information System (INIS)

    2016-01-01

    Vic Montemayor - No one has been more passionate about improving the quality and effectiveness of the teaching of Medical Physics than Bill Hendee. It was in August of 2008 that the first AAPM Workshop on Becoming a Better Teacher of Medical Physics was held, organized and run by Bill Hendee. This was followed up in July of 2010 with a summer school on the same topic, again organized by Bill. There has been continued interest in alternate approaches to teaching medical physics since those initial gatherings. The momentum established by these workshops is made clear each year in the annual Innovation in Medical Physics Education session, which highlights work being done in all forms of medical physics education, from one-on-one residencies or classroom presentations to large-scale program revisions and on-line resources for international audiences. This symposium, presented on behalf of the Education Council, highlights the work of three finalists from past Innovation in Education sessions. Each will be presenting their approaches to and innovations in teaching medical physics. It is hoped that audience members interested in trying something new in their teaching of medical physics will find some of these ideas and approaches readily applicable to their own classrooms. Rebecca Howell - The presentation will discuss ways to maximize classroom learning, i.e., increasing the amount of material covered while also enhancing students’ understanding of the broader implications of the course topics. Specifically, the presentation will focus on two teaching methodologies, project based learning and flip learning. These teaching methods will be illustrated using an example of graduate medical physics course where both are used in conjunction with traditional lectures. Additionally, the presentation will focus on our experience implementing these methods including challenges that were overcome. Jay Burmeister - My presentation will discuss the incorporation of active

  18. SU-A-BRA-05: Panel Discussion

    International Nuclear Information System (INIS)

    Montemayor, V.

    2016-01-01

    Vic Montemayor - No one has been more passionate about improving the quality and effectiveness of the teaching of Medical Physics than Bill Hendee. It was in August of 2008 that the first AAPM Workshop on Becoming a Better Teacher of Medical Physics was held, organized and run by Bill Hendee. This was followed up in July of 2010 with a summer school on the same topic, again organized by Bill. There has been continued interest in alternate approaches to teaching medical physics since those initial gatherings. The momentum established by these workshops is made clear each year in the annual Innovation in Medical Physics Education session, which highlights work being done in all forms of medical physics education, from one-on-one residencies or classroom presentations to large-scale program revisions and on-line resources for international audiences. This symposium, presented on behalf of the Education Council, highlights the work of three finalists from past Innovation in Education sessions. Each will be presenting their approaches to and innovations in teaching medical physics. It is hoped that audience members interested in trying something new in their teaching of medical physics will find some of these ideas and approaches readily applicable to their own classrooms. Rebecca Howell - The presentation will discuss ways to maximize classroom learning, i.e., increasing the amount of material covered while also enhancing students’ understanding of the broader implications of the course topics. Specifically, the presentation will focus on two teaching methodologies, project based learning and flip learning. These teaching methods will be illustrated using an example of graduate medical physics course where both are used in conjunction with traditional lectures. Additionally, the presentation will focus on our experience implementing these methods including challenges that were overcome. Jay Burmeister - My presentation will discuss the incorporation of active

  19. SU-A-BRA-02: Making the Most of a One Hour Lecture with Alternative Teaching Methodologies: Implementing Project-Based and Flipped Learning

    International Nuclear Information System (INIS)

    Howell, R.

    2016-01-01

    Vic Montemayor - No one has been more passionate about improving the quality and effectiveness of the teaching of Medical Physics than Bill Hendee. It was in August of 2008 that the first AAPM Workshop on Becoming a Better Teacher of Medical Physics was held, organized and run by Bill Hendee. This was followed up in July of 2010 with a summer school on the same topic, again organized by Bill. There has been continued interest in alternate approaches to teaching medical physics since those initial gatherings. The momentum established by these workshops is made clear each year in the annual Innovation in Medical Physics Education session, which highlights work being done in all forms of medical physics education, from one-on-one residencies or classroom presentations to large-scale program revisions and on-line resources for international audiences. This symposium, presented on behalf of the Education Council, highlights the work of three finalists from past Innovation in Education sessions. Each will be presenting their approaches to and innovations in teaching medical physics. It is hoped that audience members interested in trying something new in their teaching of medical physics will find some of these ideas and approaches readily applicable to their own classrooms. Rebecca Howell - The presentation will discuss ways to maximize classroom learning, i.e., increasing the amount of material covered while also enhancing students’ understanding of the broader implications of the course topics. Specifically, the presentation will focus on two teaching methodologies, project based learning and flip learning. These teaching methods will be illustrated using an example of graduate medical physics course where both are used in conjunction with traditional lectures. Additionally, the presentation will focus on our experience implementing these methods including challenges that were overcome. Jay Burmeister - My presentation will discuss the incorporation of active

  20. SU-A-BRA-01: Introduction

    International Nuclear Information System (INIS)

    Montemayor, V.

    2016-01-01

    Vic Montemayor - No one has been more passionate about improving the quality and effectiveness of the teaching of Medical Physics than Bill Hendee. It was in August of 2008 that the first AAPM Workshop on Becoming a Better Teacher of Medical Physics was held, organized and run by Bill Hendee. This was followed up in July of 2010 with a summer school on the same topic, again organized by Bill. There has been continued interest in alternate approaches to teaching medical physics since those initial gatherings. The momentum established by these workshops is made clear each year in the annual Innovation in Medical Physics Education session, which highlights work being done in all forms of medical physics education, from one-on-one residencies or classroom presentations to large-scale program revisions and on-line resources for international audiences. This symposium, presented on behalf of the Education Council, highlights the work of three finalists from past Innovation in Education sessions. Each will be presenting their approaches to and innovations in teaching medical physics. It is hoped that audience members interested in trying something new in their teaching of medical physics will find some of these ideas and approaches readily applicable to their own classrooms. Rebecca Howell - The presentation will discuss ways to maximize classroom learning, i.e., increasing the amount of material covered while also enhancing students’ understanding of the broader implications of the course topics. Specifically, the presentation will focus on two teaching methodologies, project based learning and flip learning. These teaching methods will be illustrated using an example of graduate medical physics course where both are used in conjunction with traditional lectures. Additionally, the presentation will focus on our experience implementing these methods including challenges that were overcome. Jay Burmeister - My presentation will discuss the incorporation of active

  1. SU-A-BRA-03: Creative Stimulation: A Flexible Hands-On Approach to Building a Deeper Understanding of Critical Concepts in Radiation Physics

    International Nuclear Information System (INIS)

    Naqvi, S.

    2016-01-01

    Vic Montemayor - No one has been more passionate about improving the quality and effectiveness of the teaching of Medical Physics than Bill Hendee. It was in August of 2008 that the first AAPM Workshop on Becoming a Better Teacher of Medical Physics was held, organized and run by Bill Hendee. This was followed up in July of 2010 with a summer school on the same topic, again organized by Bill. There has been continued interest in alternate approaches to teaching medical physics since those initial gatherings. The momentum established by these workshops is made clear each year in the annual Innovation in Medical Physics Education session, which highlights work being done in all forms of medical physics education, from one-on-one residencies or classroom presentations to large-scale program revisions and on-line resources for international audiences. This symposium, presented on behalf of the Education Council, highlights the work of three finalists from past Innovation in Education sessions. Each will be presenting their approaches to and innovations in teaching medical physics. It is hoped that audience members interested in trying something new in their teaching of medical physics will find some of these ideas and approaches readily applicable to their own classrooms. Rebecca Howell - The presentation will discuss ways to maximize classroom learning, i.e., increasing the amount of material covered while also enhancing students’ understanding of the broader implications of the course topics. Specifically, the presentation will focus on two teaching methodologies, project based learning and flip learning. These teaching methods will be illustrated using an example of graduate medical physics course where both are used in conjunction with traditional lectures. Additionally, the presentation will focus on our experience implementing these methods including challenges that were overcome. Jay Burmeister - My presentation will discuss the incorporation of active

  2. SU-A-BRA-02: Making the Most of a One Hour Lecture with Alternative Teaching Methodologies: Implementing Project-Based and Flipped Learning

    Energy Technology Data Exchange (ETDEWEB)

    Howell, R. [UT MD Anderson Cancer Center (United States)

    2016-06-15

    Vic Montemayor - No one has been more passionate about improving the quality and effectiveness of the teaching of Medical Physics than Bill Hendee. It was in August of 2008 that the first AAPM Workshop on Becoming a Better Teacher of Medical Physics was held, organized and run by Bill Hendee. This was followed up in July of 2010 with a summer school on the same topic, again organized by Bill. There has been continued interest in alternate approaches to teaching medical physics since those initial gatherings. The momentum established by these workshops is made clear each year in the annual Innovation in Medical Physics Education session, which highlights work being done in all forms of medical physics education, from one-on-one residencies or classroom presentations to large-scale program revisions and on-line resources for international audiences. This symposium, presented on behalf of the Education Council, highlights the work of three finalists from past Innovation in Education sessions. Each will be presenting their approaches to and innovations in teaching medical physics. It is hoped that audience members interested in trying something new in their teaching of medical physics will find some of these ideas and approaches readily applicable to their own classrooms. Rebecca Howell - The presentation will discuss ways to maximize classroom learning, i.e., increasing the amount of material covered while also enhancing students’ understanding of the broader implications of the course topics. Specifically, the presentation will focus on two teaching methodologies, project based learning and flip learning. These teaching methods will be illustrated using an example of graduate medical physics course where both are used in conjunction with traditional lectures. Additionally, the presentation will focus on our experience implementing these methods including challenges that were overcome. Jay Burmeister - My presentation will discuss the incorporation of active

  3. SU-A-BRA-04: Incorporating Active Learning Into Medical Physics Education

    Energy Technology Data Exchange (ETDEWEB)

    Burmeister, J. [Wayne State University School of Medicine, Detroit, MI (United States)

    2016-06-15

    Vic Montemayor - No one has been more passionate about improving the quality and effectiveness of the teaching of Medical Physics than Bill Hendee. It was in August of 2008 that the first AAPM Workshop on Becoming a Better Teacher of Medical Physics was held, organized and run by Bill Hendee. This was followed up in July of 2010 with a summer school on the same topic, again organized by Bill. There has been continued interest in alternate approaches to teaching medical physics since those initial gatherings. The momentum established by these workshops is made clear each year in the annual Innovation in Medical Physics Education session, which highlights work being done in all forms of medical physics education, from one-on-one residencies or classroom presentations to large-scale program revisions and on-line resources for international audiences. This symposium, presented on behalf of the Education Council, highlights the work of three finalists from past Innovation in Education sessions. Each will be presenting their approaches to and innovations in teaching medical physics. It is hoped that audience members interested in trying something new in their teaching of medical physics will find some of these ideas and approaches readily applicable to their own classrooms. Rebecca Howell - The presentation will discuss ways to maximize classroom learning, i.e., increasing the amount of material covered while also enhancing students’ understanding of the broader implications of the course topics. Specifically, the presentation will focus on two teaching methodologies, project based learning and flip learning. These teaching methods will be illustrated using an example of graduate medical physics course where both are used in conjunction with traditional lectures. Additionally, the presentation will focus on our experience implementing these methods including challenges that were overcome. Jay Burmeister - My presentation will discuss the incorporation of active

  4. SU-A-BRA-00: Education Council Symposium: Revitalizing Your Medical Physics Classroom: Some Examples and Thoughts from the Trenches

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2016-06-15

    Vic Montemayor - No one has been more passionate about improving the quality and effectiveness of the teaching of Medical Physics than Bill Hendee. It was in August of 2008 that the first AAPM Workshop on Becoming a Better Teacher of Medical Physics was held, organized and run by Bill Hendee. This was followed up in July of 2010 with a summer school on the same topic, again organized by Bill. There has been continued interest in alternate approaches to teaching medical physics since those initial gatherings. The momentum established by these workshops is made clear each year in the annual Innovation in Medical Physics Education session, which highlights work being done in all forms of medical physics education, from one-on-one residencies or classroom presentations to large-scale program revisions and on-line resources for international audiences. This symposium, presented on behalf of the Education Council, highlights the work of three finalists from past Innovation in Education sessions. Each will be presenting their approaches to and innovations in teaching medical physics. It is hoped that audience members interested in trying something new in their teaching of medical physics will find some of these ideas and approaches readily applicable to their own classrooms. Rebecca Howell - The presentation will discuss ways to maximize classroom learning, i.e., increasing the amount of material covered while also enhancing students’ understanding of the broader implications of the course topics. Specifically, the presentation will focus on two teaching methodologies, project based learning and flip learning. These teaching methods will be illustrated using an example of graduate medical physics course where both are used in conjunction with traditional lectures. Additionally, the presentation will focus on our experience implementing these methods including challenges that were overcome. Jay Burmeister - My presentation will discuss the incorporation of active

  5. SU-A-BRA-01: Introduction

    Energy Technology Data Exchange (ETDEWEB)

    Montemayor, V. [Germantown Academy (United States)

    2016-06-15

    Vic Montemayor - No one has been more passionate about improving the quality and effectiveness of the teaching of Medical Physics than Bill Hendee. It was in August of 2008 that the first AAPM Workshop on Becoming a Better Teacher of Medical Physics was held, organized and run by Bill Hendee. This was followed up in July of 2010 with a summer school on the same topic, again organized by Bill. There has been continued interest in alternate approaches to teaching medical physics since those initial gatherings. The momentum established by these workshops is made clear each year in the annual Innovation in Medical Physics Education session, which highlights work being done in all forms of medical physics education, from one-on-one residencies or classroom presentations to large-scale program revisions and on-line resources for international audiences. This symposium, presented on behalf of the Education Council, highlights the work of three finalists from past Innovation in Education sessions. Each will be presenting their approaches to and innovations in teaching medical physics. It is hoped that audience members interested in trying something new in their teaching of medical physics will find some of these ideas and approaches readily applicable to their own classrooms. Rebecca Howell - The presentation will discuss ways to maximize classroom learning, i.e., increasing the amount of material covered while also enhancing students’ understanding of the broader implications of the course topics. Specifically, the presentation will focus on two teaching methodologies, project based learning and flip learning. These teaching methods will be illustrated using an example of graduate medical physics course where both are used in conjunction with traditional lectures. Additionally, the presentation will focus on our experience implementing these methods including challenges that were overcome. Jay Burmeister - My presentation will discuss the incorporation of active

  6. SU-A-BRA-05: Panel Discussion

    Energy Technology Data Exchange (ETDEWEB)

    Montemayor, V. [Germantown Academy (United States)

    2016-06-15

    Vic Montemayor - No one has been more passionate about improving the quality and effectiveness of the teaching of Medical Physics than Bill Hendee. It was in August of 2008 that the first AAPM Workshop on Becoming a Better Teacher of Medical Physics was held, organized and run by Bill Hendee. This was followed up in July of 2010 with a summer school on the same topic, again organized by Bill. There has been continued interest in alternate approaches to teaching medical physics since those initial gatherings. The momentum established by these workshops is made clear each year in the annual Innovation in Medical Physics Education session, which highlights work being done in all forms of medical physics education, from one-on-one residencies or classroom presentations to large-scale program revisions and on-line resources for international audiences. This symposium, presented on behalf of the Education Council, highlights the work of three finalists from past Innovation in Education sessions. Each will be presenting their approaches to and innovations in teaching medical physics. It is hoped that audience members interested in trying something new in their teaching of medical physics will find some of these ideas and approaches readily applicable to their own classrooms. Rebecca Howell - The presentation will discuss ways to maximize classroom learning, i.e., increasing the amount of material covered while also enhancing students’ understanding of the broader implications of the course topics. Specifically, the presentation will focus on two teaching methodologies, project based learning and flip learning. These teaching methods will be illustrated using an example of graduate medical physics course where both are used in conjunction with traditional lectures. Additionally, the presentation will focus on our experience implementing these methods including challenges that were overcome. Jay Burmeister - My presentation will discuss the incorporation of active

  7. SU-A-BRA-03: Creative Stimulation: A Flexible Hands-On Approach to Building a Deeper Understanding of Critical Concepts in Radiation Physics

    Energy Technology Data Exchange (ETDEWEB)

    Naqvi, S. [Saint Agnes Cancer Institute, Baltimore, MD (United States)

    2016-06-15

    Vic Montemayor - No one has been more passionate about improving the quality and effectiveness of the teaching of Medical Physics than Bill Hendee. It was in August of 2008 that the first AAPM Workshop on Becoming a Better Teacher of Medical Physics was held, organized and run by Bill Hendee. This was followed up in July of 2010 with a summer school on the same topic, again organized by Bill. There has been continued interest in alternate approaches to teaching medical physics since those initial gatherings. The momentum established by these workshops is made clear each year in the annual Innovation in Medical Physics Education session, which highlights work being done in all forms of medical physics education, from one-on-one residencies or classroom presentations to large-scale program revisions and on-line resources for international audiences. This symposium, presented on behalf of the Education Council, highlights the work of three finalists from past Innovation in Education sessions. Each will be presenting their approaches to and innovations in teaching medical physics. It is hoped that audience members interested in trying something new in their teaching of medical physics will find some of these ideas and approaches readily applicable to their own classrooms. Rebecca Howell - The presentation will discuss ways to maximize classroom learning, i.e., increasing the amount of material covered while also enhancing students’ understanding of the broader implications of the course topics. Specifically, the presentation will focus on two teaching methodologies, project based learning and flip learning. These teaching methods will be illustrated using an example of graduate medical physics course where both are used in conjunction with traditional lectures. Additionally, the presentation will focus on our experience implementing these methods including challenges that were overcome. Jay Burmeister - My presentation will discuss the incorporation of active

  8. THERMAL COMFORT STUDY OF TEACHERS' ROOM AT SEKOLAH BINA MULIA PONTIANAK

    Directory of Open Access Journals (Sweden)

    Albert Suryajaya

    2014-01-01

    tersebut dalam tiga hari pengamatan adalah 0,130 dan merupakan kondisi netral. Ini artinya ruangan tersebut nyaman bagi penggunanya, yang pada dasarnya dikarenakan sistem jendela, pelindung matahari, dan material bangunan dapat mendukung ventilasi udara alami pada bangunan   REFERENCES Alucci, Marcia Peinando; Leonardo Marques Monteiro. 2009. Thermal Comfort Index for The Assessment of Outdoor Urban Spaces in Subtropical Climates. University of Sao Paulo. Sao Paulo Brager, G.S. and R. de Dear. 2001. Climate, Comfort, & Natural Ventilation: A new adaptive comfort standard for ASHRAE Standard 55. University of California. Berkeley. Charles, Kate E. 2003. Fanger’s Thermal Comfort and Draught Models. Institute for Research in Construction. Ottawa Darby, Sarah and Rebecca White. 2005. Thermal Comfort. University of Oxford. London Hensen, J.L.M. 1990. Literature Review on Thermal Comfort in Tranisent Conditions. Eindhoven University of Technology. Eindhoven Mangunwijaya, Yusuf Bilyarta. 1929. Pengantar Fisika Bangunan. Djambatan. Jakarta Mors, Sanderter, Jan L. M. Hensen, Marcel Loomans, Atze Boerstra. 2011. Adaptive thermal comfort in primary school classrooms: Creating and validating PMV-based comfort charts. Eindhoven University of Technology. Eindhoven Orosa, Jose A. 2009. Research on the Origins of Thermal Comfort. University of A Coruña. A Coruña Parsons, Ken. 2003. Human Thermal Environments: The effect of Hot, Modern, and Cold Environments on Human Health, Comfort, and Performance. Tj International Ltd. Cornwall Pau, J.S., William K.S. Pao, Shaharin A. Sulaiman, and E. Halawa. 2013. Adaptive Thermal’s Model for Optimum Thermal Comfort Setting fo Lecture Halls in Malaysia. CREAM - Current Research in Malaysia Vol.2, No. 2 Satwiko, Prasasto. 2005. Fisika Bangunan 1 Edisi 2. Andi. Yogyakarta

  9. SU-A-BRA-04: Incorporating Active Learning Into Medical Physics Education

    International Nuclear Information System (INIS)

    Burmeister, J.

    2016-01-01

    Vic Montemayor - No one has been more passionate about improving the quality and effectiveness of the teaching of Medical Physics than Bill Hendee. It was in August of 2008 that the first AAPM Workshop on Becoming a Better Teacher of Medical Physics was held, organized and run by Bill Hendee. This was followed up in July of 2010 with a summer school on the same topic, again organized by Bill. There has been continued interest in alternate approaches to teaching medical physics since those initial gatherings. The momentum established by these workshops is made clear each year in the annual Innovation in Medical Physics Education session, which highlights work being done in all forms of medical physics education, from one-on-one residencies or classroom presentations to large-scale program revisions and on-line resources for international audiences. This symposium, presented on behalf of the Education Council, highlights the work of three finalists from past Innovation in Education sessions. Each will be presenting their approaches to and innovations in teaching medical physics. It is hoped that audience members interested in trying something new in their teaching of medical physics will find some of these ideas and approaches readily applicable to their own classrooms. Rebecca Howell - The presentation will discuss ways to maximize classroom learning, i.e., increasing the amount of material covered while also enhancing students’ understanding of the broader implications of the course topics. Specifically, the presentation will focus on two teaching methodologies, project based learning and flip learning. These teaching methods will be illustrated using an example of graduate medical physics course where both are used in conjunction with traditional lectures. Additionally, the presentation will focus on our experience implementing these methods including challenges that were overcome. Jay Burmeister - My presentation will discuss the incorporation of active

  10. The 23rd Stirling Physics Meeting

    Science.gov (United States)

    1998-01-01

    This was how the chairman, Dennis Chisholm, described the morning's major topic `Higher Still' - the proposed successor to the Scottish Higher Grade and Sixth Year Studies Certificates. It was chosen for this one-day conference on 21 May as the documentation for it had been promised for 1 May. Alas, as the main speaker, Mary Webster, admitted, the materials were still `sitting in a warehouse in Dundee' and the programme has now been postponed for a year! Nevertheless the team, which included Rothwell Glen and Tony Keeley, bravely fielded a series of awkward questions from a critical audience of over 200 physics teachers. Physics with gusto If `Higher Still' was a damp squib Rebecca Crawford's team from Glasgow Science and Technology Outreach set the place ablaze. In their first spectacular demonstration Rebecca lay on a bed of sharp nails while someone stood on top of her! This was followed by a deafening explosion produced by cornflour powder igniting in a tin can used to model a grain silo. Hydrogen was then produced by aluminium foil in a solution of caustic soda, and used to inflate a balloon before exploding it with a flaming torch. Using two 2 mW lasers the green spot produced by one was shown to appear much brighter than the red spot from the other, The Australian demonstrator explained that some of their fire engines were now being painted green instead of red as our eyes are more sensitive to green. A small low-inertia electric motor turned when attached to copper and zinc electrodes inserted first in a glass of Coke and then in a fresh grapefruit. Gas-filled sausage balloons were packed into a flask of liquid nitrogen where they collapsed as the gas inside liquefied. When the bunch of deflated balloons was removed and thrown on to the bench the results were dramatic. As you might expect, the `best wine' was kept to the last. Kenneth Skeldon and two colleagues in the University of Glasgow have built a high voltage generator based on a resonant transformer

  11. Selected abstracts from the Breastfeeding and Feminism International Conference 2016

    Directory of Open Access Journals (Sweden)

    Lisa H. Amir

    2016-10-01

    Full Text Available Table of contents A1. Infant feeding and poverty: a public health perspective in a global context Lisa H. Amir A2. Mothers’ experiences with galactagogues for lactation: an exploratory cross sectional study Alessandra Bazzano, Shelley Thibeau, Katherine P. Theall A3. The motherhood journey and breastfeeding: from self-efficacy to resilience and social stigma Anna Blair, Karin Cadwell A4. Breastfeeding as an evolutionary adaptive behavior Emily A. Bronson A5. Conflict-of-interest in public health policy: as real as that logo on your website Elizabeth C. Brooks A6. Co-opting sisterhood and motherhood: behind the scenes of Similac’s aggressive social media campaigns Jodine Chase A7. The exclusion of women from the definition of exclusive breastfeeding Ellen Chetwynd, Rebecca Costello, Kathryn Wouk A8. Healthy maternity policies in the workplace: a state health department’s experience with the “Bring Your Infant to Work” program Lindsey Dermid-Gray A9. Implications for a paradigm shift: factors related to breastfeeding among African American women Stephanie Devane-Johnson, Cheryl Woods Giscombe, Miriam Labbok A10. Social experiences of breastfeeding: building bridges between research and policy: an ESRC-funded seminar series in the UK Sally Dowling A11. Manager’s perspectives of lactation breaks Melanie Fraser A12. The challenging second night: a dialogue from two perspectives Jane Grassley, Deborah McCarter-Spaulding, Becky Spencer A13. The role of lactation consultants in two council breastfeeding services in Melbourne, Australia – some preliminary impressions Jennifer Hocking, Pranee Liamputtong A14. Integrating social marketing and community engagement concepts in community breastfeeding programs Sheree H. Keitt, Harumi Reis-Reilly A15. What happens before and after the maternity stay? Creating a community-wide Ten Steps approach Miriam Labbok A16. #RVABREASTFEEDS: cultivating a breastfeeding-friendly community Leslie Lytle A17

  12. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2003-01-01

    leadership, legitimacy and populist politics. Kingston: Ian Randle; Boulder CO: Lynne Rienner, 2001. xvi + 264 pp. -Bill Maurer, Cynthia Weber, Faking it: U.S. Hegemony in a 'post-phallic' era. Minneapolis: University of Minnesota Press, 1999. xvi + 151 pp. -Kelvin Santiago-Valles, Christina Duffy Burnett ,Foreign in a domestic sense: Puerto Rico, American expansion, and the constitution. Durham NC: Duke University Press, 2001. xv + 422 pp., Burke Marshall (eds -Rubén Nazario, Efrén Rivera Ramos, The legal construction of identity: The judicial and social legacy of American colonialism in Puerto Rico. Washington DC: American Psychological Association, 2000. 275 pp. -Marc McLeod, Louis A. Pérez, Jr., Winds of change: Hurricanes and the transformation of nineteenth-century Cuba. Chapel Hill: University of North Carolina Press, 2001. x + 199 pp. -Jorge L. Giovannetti, Fernando Martínez Heredia ,Espacios, silencios y los sentidos de la libertad: Cuba entre 1878 y 1912. Havana: Ediciones Unión, 2001. 359 pp., Rebecca J. Scott, Orlando F. García Martínez (eds -Reinaldo L. Román, Miguel Barnet, Afro-Cuban religions. Princeton NJ: Markus Wiener Publishers, 2001. 170 pp. -Philip W. Scher, Hollis 'Chalkdust' Liverpool, Rituals of power and rebellion: The carnival tradition in Trinidad and Tobago, 1763-1962. Chicago: Research Associates School Times Publications and Frontline distribution international, 2001. xviii + 518 pp. -Asmund Weltzien, David Griffith ,Fishers at work, workers at sea: A Puerto Rican journey through labor and refuge. Philadelphia PA: Temple University Press, 2002. xiv + 265 pp., Manuel Valdés Pizzini (eds -Riva Berleant-Schiller, Eudine Barriteau, The political economy of gender in the twentieth-century Caribbean. New York: Palgrave, 2001. xvi + 214 pp. -Edward Dew, Rosemarijn Hoefte ,Twentieth-century Suriname: Continuities and discontinuities in a new world society. Kingston: Ian Randle; Leiden: KITLV Press, 2001. xvi + 365 pp., Peter Meel (eds -Joseph

  13. Bilimsel Toplantı Duyuruları

    Directory of Open Access Journals (Sweden)

    Adli Tıp Uzmanları Derneği ATUD

    2007-08-01

    Full Text Available VII. Adli Bilimler Sempozyumu 24-27 Mayıs 2007 Gaziantep, Türkiye İletişim: Yrd.Doç.Dr.Aysun Baransel Isırr Gaziantep Üniversitesi Tıp Fakültesi Adli Tıp Anabilim Dalı E-posta: aysunbaransel@yahoo.com Web: atud.org.tr 6th International Congress of the Baltic Medico-Legal Association 14.-16. June 2007 Vilnius - Lithuania Contact: Mykolas Romeris University Institute of Forensic Medicine S. Iukausko 12 LT-08234 Vilnius, Lithuania Tel: +370 5 278 90 48 Fax: +370 5 278 90 47 E-mail: congress@bmla2007.org Web: www.bmla2007.org m Mediterranean Academy of Forensic Sciences Congress V Latin-American Congress of Medical Law m Iberian Congress of Legal Medicine 21-23 June 2007 Porto, Portugal Contact: Instituto Nacional de Medicina Legal Delegaçâo do Porto Jardim Carrilho Videira 4050-167 Porto, Portugal Phone: +351 22 2073850 Fax:\t+351 22 2083978 e-mail: portocongresses2007@dpinml.mj.pt Web: www.inml.mj.pt/portocongresses2007 Human Identification: Laboratory Methods in Forensic Anthropology July 9-14, 2007 Forensic Anthropology Center University of Tennessee Knoxville, Tennessee Contact: Rebecca Wilson University of Tennessee E-mail: rwilson8@utk.edu North American Forensic Entomology Association Annual Conference July 11-13, 2007 Vancouver, British Columbia, Canada Simon Fraser University Contact: Gail Anderson Simon Fraser University E-mail: ganderso@sfu.ca Web site: http://www.nafea.net + 1-604-291-3589 (Voice Indo-Pacific Congress on Legal Medicine and Forensic Sciences of the Indo-Pacific Association of the Law, Medicine and Science (INPALMS July 22 -27, 2007 Cinnamon Grand Hotel Colombo, Sri Lanka Contact: Richard Harruff Chief Medical Examiner Seattle, Washington E-mail: richard.harruff@metrokc.gov Web site: http://www.inpalmscolombo2007.lk/ + 1-206-731-2886 Advanced Death Investigation Masters 12 Conference July 23-26, 2007 St. Louis University School of Medicine Division of Forensic Pathology St. Louis, Missouri Contact: Julie Howe

  14. Bilimsel Toplantı Duyuruları

    Directory of Open Access Journals (Sweden)

    Adli Tıp Uzmanları Derneği ATUD

    2005-12-01

    Full Text Available The 2006 Techno Security Conference The Eighth Annual International Techno Security Conference Further information : June 4-7, 2006 Myrtle Beach Marriott Resort 8400 Costa Verde Drive Myrtle Beach, SC 29572 Medical Forensic Management of Adult Sexual Assault 16-18 June 2006, Auckland Further information : Marion Davis Library Building 43, Auckland Hospital, Park Road, Grafton Auckland The 6th Annual Digital Forensic Research Workshop (DFRWS 2006 August 14-16, 2006-09-13 Further information : Purdue University Lafayette, Indiana, USA www.dfrws.org The 2006 Techno Forensics Conference November 6 - 8, 2006 Further information : Inaugural Techno Forensics Conference at the National Institute of Standards and Technology (NIST 100 Bureau Drive Administration Bldg. 101 Gaithersburg, MD 20899 http://www.techsec.com/html/TechnoForensics2006.htm The Second Islamic Countries Forensic Medicine Congress The Second Conference of Arab Forensic Pathologists and Physicians Union The First Jordanian International Conference on Forensic Sciences and Medicine 5-8 September 2006, Amman Jordan Further information : Dr Hani Jahshan Emaihhani.jahshan@jsfms.org Tel: +962 (7 5522062 http://www.jsfms.org/ Forensic Science Society Conferences 11 September 2006, United Kingdom Further information : Advances in Forensic DNA Analysis Joint Conference with Centre for Forensic Investigation, University of Teesside Innovation Centre, University of Teesside, Middlesbrough conference@forensic-science-society.org.uk Environmental Forensics Meeting: Chemical, Physical and Biological Methods, 18 - 21 September 2006, United Kingdom Further information : University of Durham, Durham, UK Contact: Rebecca Quine, Conference Promotion Executive quiner@rsc.org Forensic Neuropathology Meeting 28 September 2006,United Kingdom Further information : Royal College of Pathologists, 2 Carlton House Terrace, London, SW1Y 5AF Michelle Casey for Tel: 020 7451 6740 Email: michelle

  15. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2004-01-01

    search for home. Durham NC: Duke University Press, 2001. x + 324 pp., Georges Eugene Fouron (eds -Karen Fog Olwig, Nancy Foner, From Ellis Island to JFK: New York's two great waves of immigration. Chelsea MI: Russell Sage Foundation, 2000. xvi + 334 pp. -Aviva Chomsky, Lara Putnam, The company they kept: Migrants and the politics of gender in Caribbean Costa Rica, 1870-1960. Chapel Hill: University of North Carolina Press, 2002. xi + 303 pp. -Rebecca B. Bateman, Rosalyn Howard, Black Seminoles in the Bahamas. Gainesville: University Press of Florida, 2002. xvii + 150 pp. -Virginia Kerns, Carel Roessingh, The Belizean Garífuna: Organization of identity in an ethnic community in Central America. Amsterdam: Rozenberg. 2001. 264 pp. -Nicole Roberts, Susanna Regazzoni, Cuba: una literatura sin fronteras / Cuba: A literature beyond boundaries. Madrid: Iberoamericana/Frankfurt am Main, Germany: Vervuert, 2001. 148 pp. -Nicole Roberts, Lisa Sánchez González, Boricua literature: A literary history of the Puerto Rican Diaspora. New York: New York University Press, 2001. viii + 216 pp. -Kathleen Gyssels, Ange-Séverin Malanda, Passages II: Histoire et pouvoir dans la littérature antillo-guyanaise. Paris: Editions du Ciref, 2002. 245 pp. -Sue N. Greene, Simone A. James Alexander, Mother imagery in the novels of Afro-Caribbean women. Columbia MO: University of Missouri Press, 2001. x + 215 pp. -Gert Oostindie, Aarón Gamaliel Ramos ,Islands at the crossroads: Politics in the non-independent Caribbean., Angel Israel Rivera (eds -Katherine E. Browne, David A.B. Murray, Opacity: Gender, sexuality, race, and the 'problem' of identity in Martinique. New York: Peter Lang, 2002. xi + 188 pp. -James Houk, Kean Gibson, Comfa religion and Creole language in a Caribbean community. Albany: State University of New York Press, 2001. xvii + 243 pp. -Kelvin Singh, Frank J. Korom, Hosay Trinidad: Muharram performances in an Indo-Caribbean Diaspora.Philadelphia: University of

  16. Bilimsel Toplantı Duyuruları

    Directory of Open Access Journals (Sweden)

    Adli Tıp Uzmanları Derneği ATUD

    2007-04-01

    Contact: Rebecca Wilson University of Tennessee E-mail: rwilson8@utk.edu North American Forensic Entomology Association Annual Conference July 11-13, 2007 Vancouver, British Columbia, Canada Simon Fraser University Contact: Gail Anderson Simon Fraser University E-mail: ganderso@sfu.ca Web site: http://www.nafea.net + 1-604-291-3589 (Voice Indo-Pacific Congress on Legal Medicine and Forensic Sciences of the Indo-Pacific Association of the Law, Medicine and Science (INPALMS July 22 -27, 2007 Cinnamon Grand Flotel Colombo, Sri Lanka Contact: Richard Flarruff Chief Medical Examiner Seattle, Washington E-mail: richard.harruff@metrokc.gov Web site: http://www.inpalmscolombo2007.lk/ + 1-206-731-2886 (Voice 22nd Congress of die International Society for Forensic Genetics 21 - 25August, 2007 Copenhagen, Denmark Contact: Niels Morling, Institute of Forensic Medicine, University of Copenhagen, Congress Secretariat Welcome ApS, Billedvbej 4, l.sal, DK-2100 Copenhagen. Phone: +45 70 25 80 20. E-mail: info@welcomehome.dk. Web : www.isfg2007.org 5th ISABS Conference in Forensic Genetics and Molecular Anthropology September 3-7, 2007 Hotel Le Méridien Lav, Split, Croatia Contact: International Society for Applied Biological Sciences - ISABS Domobranska 21, HR-10000 Zagreb, Croatia Phone/Fax: ++385 1 3702 961 E-mail:info@isabs.hr The 2007 Midwestern Association of Forensic Scientists Annual Meeting September 24 - 28, 2007 Park Place Hotel in downtown Traverse City, Michigan. Contact: Guy Nutter Program Chair 248-380-1029 E-mail: NutterG@michigan.gov The 44th Congress of the European Societies of Toxicology Amsterdam 7-10 October, 2007 Contact: Eurocongres Conference Management Jan van Goyenkade 11 1075 HP Amsterdam The Netherlands http:// www.eurotox2007.org/ 2007 Annual NAME Meeting "Crime Scene Investigation:Reality (The Operations of the Medical Examiner Office in the Real World" October 12-17, 2007 Savannah Marriott Riverfront Hotel in Savannah, Contact: Mary Fran Ernst NAME Meetings

  17. There’s a kind of hush…..

    Directory of Open Access Journals (Sweden)

    Yngve Nordkvelle

    2013-11-01

    masses”. Many, many other universities, world wide, are about to follow their example. Main universities, who traditionally have failed to take interest in provide mass education, are now, all of a sudden, at the front of “the development”.In the aftermath – or hush – second thoughts start to come to the fore. One of the main entrepreneurs of “MOOC”s, Sebastian Thrun, named “the Godfather” of MOOC, and CEO of Udacity, admits the failure of the project ran with San Jose State University. He blames the poor academic quality of the students for the failure. Rebecca Schuman, a widely acclaimed columnist and educational experts comments that the MOOCs seem to fail exactly the group of students who, allegedly, would benefit the most from this way of teaching and learning. This brings us all back to square one, and underlines what veterans in the field always have said. This is a difficult enterprise. There is no salvations provided by a new technology. I would like to add: thanks for the enthusiasm, and I look forward to what comes after “the hush”.In this issue we bring a new article from Professor Theo Hug from the University of Innsbruck, Austria. This is an analytical paper that provides us with profound perspectives about what communication related to teaching and learning with media is all about. It claims that when enthusiasts, such as the those providing MOOCs, go about and introduce new trends, they are often helpless in understanding the elementary dimension of media education, or the epistemological issues of the field. Hug sums up his contribution by arguing for polylogical design principles for an educational knowledge organization.In the paper by Michaela Rizzolli, also from the University of Innsbruck, Austria, we bring another contribution aiming at shedding light on the very foundations of media education. Ms. Rizzolli studies online playgrounds and introduces us to the problems we encounter when we stick to dichotomies in our thinking about this

  18. Bilimsel Toplantı Duyuruları

    Directory of Open Access Journals (Sweden)

    Adli Tıp Uzmanları Derneği ATUD

    2006-04-01

    University Lafayette, Indiana, USA www.dfrws.org XXth Congress of International Academy of Legal Medicine in Budapest 23-26 August 2006, Hungary Venue: Corvinus University Budapest, Hungary Preliminary scientific programme: Collaboration and information exchange among specialist on an international level related to the discipline of Legal Medicine Main topics: Forensic Medicine and Pathology, Forensic Toxicology, Forensic Genetics, Forensic Anthropology and Odontology, Forensic Entomology, Forensic Psychiatry and Criminology, Forensic Psychlogy, Doping,Medical Law, Insurance Medicine, Free communications and Poster session For more information: Congress Secretariat Contact person: Alice Sipos MOTESZ Congress and Travel Agency H-1443 Budapest, POB 145. Tel.: +36 1 311 66 87; Fax: +36 1 383 79 18; E-mail: congress@motesz.hu; Internet: www.motesz. hu The 2006 Techno Forensics Conference 6-8 November, 2006 Further information: Inaugural Techno Forensics Conference at the National Institute of Standards and Technology (NIST 100 Bureau Drive Administration Bldg. 101 Gaithersburg, MD 20899 http://www.techsec.com/html/TechnoForensics2006.htm The Second Islamic Countries Forensic Medicine Congress The Second Conference of Arab Forensic Pathologists and Physicians Union The First Jordanian International Conference on Forensic Sciences and Medicine 5-8 September 2006, Amman Jordan Further information: Dr Hani Jahshan Emaihhani.jahshan@jsfms.org Tel: +962 (7 5522062 http : //www .jsfms.org/ Forensic Science Society Conferences 11 September 2006, United Kingdom Further information: Advances in Forensic DNA Analysis Joint Conference with Centre for Forensic Investigation, University of Teesside Innovation Centre, University of Teesside, Middlesbrough mailto:conference@forensic-science-society.org.uk Environmental Forensics Meeting: Chemical, Physical and Biological Methods, 18-21 September 2006, United Kingdom Further information: University of Durham, Durham, UK Contact: Rebecca Quine

  19. PREFACE: The random search problem: trends and perspectives The random search problem: trends and perspectives

    Science.gov (United States)

    da Luz, Marcos G. E.; Grosberg, Alexander; Raposo, Ernesto P.; Viswanathan, Gandhi M.

    2009-10-01

    reactive component, e.g., eating, mating, etc. From the comments above, it is clear that the subject can be treated from the perspective of different fields and subfields of physics and mathematics: statistical mechanics, stochastic processes, Lévy walks and flights, complex systems, fractal geometry, and non-linear phenomena. Some important questions in random searches, especially in the case of discrete landscapes, are also associated with graph theory, random lattices, and complex networks. The aim of this special issue is to bring together, in a single publication, all or most of the relevant theoretical concepts-ideas together with discussions of recent findings that are important for understanding the main elements of random searches. In addition, we will address the types of problems which are characteristic of random searching. Thus, we sincerely hope that this collection of works will provide a good overview for anyone interested in this field. Finally, we should thank the editors and staff of Journal of Physics A: Mathematical and Theoretical for opining that random searches are an interesting topic of research deserving a topical publication. Furthermore, we are very grateful to Rebecca Gillan for helping us at all stages of the preparation and organization of this special issue. Finally, we would like to thank the contributing authors who share with the guest editors the enthusiasm and interest for this fascinating field of research.

  20. Obituary: John P. Oliver (1939-2011)

    Science.gov (United States)

    Cohen, Howard

    2011-12-01

    evaluating observing conditions at in the visible region of the spectrum. In his last two years Oliver embarked on another unique project. In the North Irish town of Armagh, home of the Armagh Observatory, now stands a large, two-meter diameter "Celestial Sphere" made from solid polished grey granite. This impressive and beautiful star ball rests on one of four large base stones engraved to depict the story of the development of astronomy through the ages. On its surface, artist Brian Connolly has etched the brightest stars and other features of the sky in gold. The sphere is aligned north with the stars and correctly oriented toward the pole star. Although this artwork is the vision of the artist, Oliver provided the templates for the precise positions of stars and other heavenly features on the sphere. Oliver had a long interest in public programming and public schools. He actively worked with middle school science teachers, was a creator of "Conversations About Science and Mathematics" and was an innovator in large classroom teaching. He volunteered as a science- and engineering-fair judge for more than twenty years, finally stopping only about a year before his death. Members of the Alachua Astronomy Club, Inc., favorably knew him for his interesting, absorbing and clear presentations. Few could converse as well on the wide spectrum of knowledge that modern astronomy now entails. Predeceased by a son, Michael, he leaves behind his wife Barbara of forty-seven years, three children, Jennifer, Keith and Rebecca, two grandchildren, Elspeth and Moira, and a great granddaughter, Dorothy. Oliver also left behind dear friends, colleagues, students and a legacy difficult to match. He was proud of the department that he had helped shape during his long tenure at UF. Oliver was unique among many astronomers due to his abilities and flair as an excellent speaker and teacher, a superb instrumentalist and programmer, and as a talented research scientist with an unequaled passion and

  1. BOOK REVIEW: Case Studies in Knowledge Management

    Directory of Open Access Journals (Sweden)

    Reviewed by Dr. Adnan BOYACI

    2005-10-01

    .The book presents case studies explaining actual applications of KM in a different oforganizational and global settings. Different subjects and issues associated withconstruction of KM system in different kinds of organizations are explored within eachsection. Organizational learning (OL, knowledge, culture and productivity are some ofthe issues tackled with construction of KM system in a variety of organizational andglobal settings.The book is organized into seven sections; KM in support of organizational learning,knowledge management in support of retaining organizational knowledge, knowledgemanagement strategy, issues in knowledge management, KM is support of knowledgetransfer, KM in support of projects, KM outcomes. Each section is related with an area KMresearch.In section I, there are two cases discussing KM in support of OL. The first case is fromLynne P. Cooper, Rebecca L. Nash, Tu-Anh T. Phan, and Teresa R. Bailey and describesdevelopment and operation of knowledge system in order to support learning oforganizational knowledge at the Jet Propulsion Laboratory in USA. It presents in detailimplementation and rollout of the system and argues the results from performance andusage data collected over 19 weeks. The second case is from Brigette McGregor-MacDonald and describes the work of global organizations in its KM efforts to sustain andtransfer learning from global leadership curriculum. It mainly focuses on KM solution162developed to support employees to sustain their learning, to enable them to share theirinsights and experiences with others, and thus increase organizational capability.Section 2 explores using KM to support the retention of organizational knowledge inorganizations where the work forces are in transition. In third chapter in this section HaniAbdel-Aziz, and Khaled Wahba discuss the building of organizational memory informationsystem (OMIS in an Egyptian Professional Services company suffering from knowledgeloss due to high rate of employee turnover

  2. Obituary: Alexander Dalgarno (1928 - 2015)

    Science.gov (United States)

    Hartquist, Tom; Babb, James F. Babb; Loeb, Avi

    Alex Dalgarno's major contributions to the understanding of fundamental atomic and molecular processes enabled him to develop diagnostics of the physical conditions of atmospheres and astrophysical sources and to elucidate the roles of such processes in controlling those environments. He greatly influenced the research of physicists, chemists, atmospheric scientists, and astronomers, leading Sir David Bates to write, "There is no greater figure than Alex in the history of atomic physics and its applications." Alex was born and grew up in London. As a child, he enjoyed mathematical puzzles and did well at sports. He was invited to try out for the Tottenham Hotspur soccer team, but his professional sporting career ended due to an injury, which did not prevent Alex playing tennis and squash into his ninth decade. In 1945 Alex began to study Mathematics at University College London (UCL). In 1947 Sir Harrie Massey invited him to work for a PhD in Physics and suggested that Alex investigate collisions of metastable helium atoms in helium gas to determine the cross sections for excitation transfer. Richard Buckingham was Alex's immediate supervisor. After completing his graduate study in 1951, Alex became a member of staff in Applied Mathematics at the Queen's University of Belfast (QUB). He served as the Director of the Computational Laboratory after a 1954 visit to MIT, which had an electronic computer, led Alex to persuade colleagues that QUB needed one. In 1957, the poet Philip Larkin was the best man at the marriage of Alex to Barbara Kane. They had four children, Fergus, Penelope, Piers, and Rebecca, but the marriage dissolved after ten years. Alex's important work during the 1950s on the quantitative evaluation of long-range interactions underpinned his collaborations on precise scattering calculations relevant to ultra-cold collisions and the formation of atomic Bose-Einstein condensates over four decades later. He investigated the theory of atomic and molecular

  3. U.S. Geological Survey Karst Interest Group Proceedings, San Antonio, Texas, May 16–18, 2017

    Science.gov (United States)

    Kuniansky, Eve L.; Spangler, Lawrence E.

    2017-05-15

    Buffalo National River in the southern Ozarks, and a keynote presentation on paleokarst in the United States was delivered by Art and Peggy Palmer. The sixth KIG workshop was hosted by the National Cave and Karst Research Institute (NCKRI) in 2014, in Carlsbad, New Mexico. George Veni, Director of the NCKRI, served as a co-chair of the workshop with Eve Kuniansky of the USGS. The workshop featured speaker Dr. Penelope Boston, Director of Cave and Karst Studies at New Mexico Tech, Socorro, and Academic Director at the NCKRI, who addressed the future of karst research. The field trip on evaporite karst of the lower Pecos Valley was led by Lewis Land (NCKRI karst hydrologist), and the field trip on the geology of Carlsbad Caverns National Park was led by George Veni.This current seventh KIG workshop is being held in San Antonio at the University of Texas at San Antonio (UTSA). This 2017 workshop is being hosted by the Department of Geological Sciences’ Student Geological Society (SGS), and student chapters of the American Association of Petroleum Geologists (AAPG) and Association of Engineering Geologists (AEG), with support by the UTSA Department of Geological Sciences and Center for Water Research. The UTSA student chapter presidents, Jose Silvestre (SGS), John Cooper (AAPG), and Tyler Mead (AEG) serve as co-chairs of the 2017 workshop with Eve Kuniansky of the USGS. The technical session committee is chaired by Eve Kuniansky, USGS, and includes Michael Bradley, Tom Byl, Rebecca Lambert, John Lane, and James Kaufmann, all USGS, and Patrick Tucci, retired USGS. The logistics committee includes Amy Clark, Yongli Gao, and Lance Lambert (Department Chair), UTSA Department of Geological Sciences; and Ryan Banta and Allan Clark, USGS, San Antonio, Texas. The field trip committee is chaired by Allan Clark and includes Amy Clark, Yongli Gao, and Keith Muehlestein, UTSA; Marcus Gary, Edwards Aquifer Authority and University of Texas at Austin; Ron Green, Southwest Research

  4. European astronomers' successes with the Hubble Space Telescope*

    Science.gov (United States)

    1997-02-01

    vary. In dense or diffuse regions, in very young or very old agglomerations, in the Milky Way Galaxy or elsewhere, the relative numbers of stars of different masses are always roughly the same. Evidently Nature mass-produces quotas of large and small stars irrespective of circumstances. This discovery will assist astronomers in making sense of very distant and early galaxies. They can assume that the stars are of the most familiar kinds. Another surprise was spotted by Rebecca Elson in Gilmore's team, in long-exposure images of the giant galaxy M87, in the nearby Virgo cluster. It possesses globular clusters of very different ages. In the Milky Way and its similar spiral neighbour, the Andromeda galaxy, globular clusters contain the oldest stars. While M87 has ancient globular clusters too, some are different in colour and much younger. The theory is that they were manufactured during collisions of the galaxies that merged into M87, making it the egg-shaped giant seen today. If so, the absence of young globular clusters in the Milky Way may mean that our Galaxy has never suffered a major collision. Accidents in the galactic traffic Brighter than a million million suns, a quasar is the most powerful lamp in the Universe. Astronomers understand it to be powered by matter falling into a massive black hole in the heart of a galaxy. Mike Disney of the University of Wales, Cardiff, leads a European team that asks why some thousands of galaxies harbour quasars, in contrast to the billions that do not. In almost every case that he and his colleagues have investigated, using Hubble's WFPC2 camera at its highest resolution, they see the quasar's home galaxy involved in a collision with another galaxy. "It's my opinion that almost any galaxy can be a quasar," Disney says, "if only its central black hole gets enough to eat. In the galactic traffic accidents that Hubble reveals, we can visualize fresh supplies of stars and gas being driven into the black hole's clutches. My

  5. PREFACE: Complex Networks: from Biology to Information Technology

    Science.gov (United States)

    Barrat, A.; Boccaletti, S.; Caldarelli, G.; Chessa, A.; Latora, V.; Motter, A. E.

    2008-06-01

    appeal to both experts and newcomers to the field. Finally, we would like to thank all participants of the workshop for their very significant contributions and the IOP Publishing team, particularly Rebecca Gillan, for the careful production of this special issue.

  6. From the Editor

    Directory of Open Access Journals (Sweden)

    Ugur Demiray

    2005-09-01

    leadership and managerial implications of recent developments for higher education. Reviewing unique characteristics and the fundamental changes shaping higher education, the paper examines the need for organizational transformation and the major managerial implications. When we click the nineth paper you will see the article which is written by Prof. Dele BRAIMOH, National University of Lesotho, SOUTH AFRICA and Dr. Rebecca LEKOKO, University of Botswana, South Africa. My dear authors indicate in their paper aim is to stimulate dialogue on the significance, scope of coverage and the processes of formulating a policy framework for maintaining academic excellence as opposed to mediocrity. We are, however, mindful of the fact that practices are diverse in the region, but regardless of this diversity, a regional policy framework is possible to regulate the planning, development and implementation of quality distance education Programmes across all levels of education, with particular focus on higher institutions of learning. The tenth article was sent to TOJDE by Dr. I. Ahmed M. J. SADIIG is from Malaysia, International Islamic University Gombak. Dr. I. Ahmed M. J. SADIIG emphasizes in his article that the traditional learning paradigm involving face-to-face interaction with students is shifting to highly data-intensive electronic learning with the advances in Information and Communication Technology. An important component of the e-learning process is the delivery of the learning contents to their intended audience over a network. A distributed learning system is dependent on the network for the efficient delivery of its contents to the user. Next article is again from Malaysia, which written by group of Hanafi ATAN, Zuraidah A. RAHMAN, Omar MAJID, Noraida A. GHANI and Rozhan M IDRUS. In their article, they discuss on “The Support System in Distance Education: Factors Affecting Achievements Among Women Learners”. It is very important subject for TOJDE’s publishing