Calculation of radon concentration in water by toluene extraction method

Energy Technology Data Exchange (ETDEWEB)

Saito, Masaaki [Tokyo Metropolitan Isotope Research Center (Japan)

1997-02-01

Noguchi method and Horiuchi method have been used as the calculation method of radon concentration in water. Both methods have two problems in the original, that is, the concentration calculated is changed by the extraction temperature depend on the incorrect solubility data and the concentration calculated are smaller than the correct values, because the radon calculation equation does not true to the gas-liquid equilibrium theory. However, the two problems are solved by improving the radon equation. I presented the Noguchi-Saito equation and the constant B of Horiuchi-Saito equation. The calculating results by the improved method showed about 10% of error. (S.Y.)

Sample Set (SE): SE58 [Metabolonote[Archive

Lifescience Database Archive (English)

Full Text Available greatly facilitates data interpretation, quality control and method comparisons. Henning Redestig, Makoto K...obayashi, Kazuki Saito, Miyako Kusano Henning R et al. (2011) Analytical Chemistry 83: 5645-5651 ...

Gender-divergent expression of lipid and bile acid metabolism ...

Indian Academy of Sciences (India)

33

3Division of Basic Medical Science, Kindai University Faculty of Medicine, .... 2.2 Quantification of Serum Biochemical Markers and Hepatic Triglycerides ..... The authors would like to thank Yoko Saito and Mariko Shibayama for technical.

St. John's Wort

Science.gov (United States)

... of Grants and Contracts General Award Mechanisms Small Business Research Grant Program (SBIR) Funding for: Natural Product Research ... or citalopram: failure to show benefit over placebo . Journal of Psychiatric Research. 2011;45(7):931-941. Saito YA, Rey ...

Vogue and the possibility of cosmopolitics: race, health and cosmopolitan engagement in the global beauty industry

NARCIS (Netherlands)

Kuipers, G.M.M.; Chow, Y.F.; van der Laan, E.

2014-01-01

This article explores the possibility of cosmopolitics, using the global magazine franchise Vogue as our starting point. Drawing on Saito's conceptualizations of cosmopolitanism, we investigate whether Vogue promotes cosmopolitan engagement, which we define as promotion of human diversity, cultural

Reference: 691 [Arabidopsis Phenome Database[Archive

Lifescience Database Archive (English)

Full Text Available 691 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u18024555i Watanabe Mutsu...ogy Fukushima Atsushi|Kusano Miyako|Noji Masaaki|Oikawa Akira|Saito Kazuki|Watanabe Mutsumi

Estuarine morphodynamic adaptation to sediment supply and human activities : A case study of turbidity maximum

NARCIS (Netherlands)

Zhu, C.; Guo, L; Tian, B.; He, Q; Wang, Zhengbing

2017-01-01

Estuarine morphodynamics undergo significant changes due to declined sediment supply from river, rising sea-level, and human interferences (Syvitski and Saito, 2007; Syvitski et al., 2009). The Yangtze Estuary is such a case whose decadal morphodynamic evolution was broadly examined. It was

Local duality for 2-dimensional local ring

Indian Academy of Sciences (India)

dimensional complete local ring whose residue field is an n-dimensional local field in the sense of. Kato–Parshin. Our results generalize the Saito works in the case n = 0 and are applied to study the Bloch–Ogus complex for such rings in various cases.

A cross-cultural comparison study of the production of simple rhythmic patterns

NARCIS (Netherlands)

Sadakata, M.; Ohgushi, K.; Desain, P.W.M.

2004-01-01

It has been argued that Japanese and western musicians give different impressions to the listener when performing western music (Saito, 1999; Shibata, 1987). However, these claims are mostly based on subjective impressions and very few studies provide corroborative empirical evidence. The aim of the

11 August 2008 - Member of the House of Councillors M. Naito (The National Diet of Japan, The Democratic Party of Japan) signing the guest book with CERN Director-General R. Aymar.

CERN Document Server

Maximilien Brice

2008-01-01

Also present: ATLAS Collaboration Spokesperson P. Jenni, ATLAS Collaboration and University of Tokyo T. Kawamoto Adviser for Non-Member State Relations J. Ellis Deputy Director-General, Chief Scientific Officer J. Engelen ATLAS Collaboration and KEK T.Kondo Second Secretary, Permanent Mission of Japan in Geneva K. Saito

The extended reciprocity: Strong belief outperforms persistence.

Science.gov (United States)

Kurokawa, Shun

2017-05-21

The existence of cooperation is a mysterious phenomenon and demands explanation, and direct reciprocity is one key potential explanation for the evolution of cooperation. Direct reciprocity allows cooperation to evolve for cooperators who switch their behavior on the basis of information about the opponent's behavior. Here, relevant to direct reciprocity is information deficiency. When the opponent's last move is unknown, how should players behave? One possibility is to choose cooperation with some default probability without using any further information. In fact, our previous paper (Kurokawa, 2016a) examined this strategy. However, there might be beneficial information other than the opponent's last move. A subsequent study of ours (Kurokawa, 2017) examined the strategy which uses the own last move when the opponent's last move is unknown, and revealed that referring to the own move and trying to imitate it when information is absent is beneficial. Is there any other beneficial information else? How about strong belief (i.e., have infinite memory and believe that the opponent's behavior is unchanged)? Here, we examine the evolution of strategies with strong belief. Analyzing the repeated prisoner's dilemma game and using evolutionarily stable strategy (ESS) analysis against an invasion by unconditional defectors, we find the strategy with strong belief is more likely to evolve than the strategy which does not use information other than the opponent player's last move and more likely to evolve than the strategy which uses not only the opponent player's last move but also the own last move. Strong belief produces the extended reciprocity and facilitates the evolution of cooperation. Additionally, we consider the two strategies game between strategies with strong belief and any strategy, and we consider the four strategies game in which unconditional cooperators, unconditional defectors, pessimistic reciprocators with strong belief, and optimistic reciprocators with

Kontsert

Index Scriptorium Estoniae

2006-01-01

Kontserdist "Isad ja pojad - Uno, Tõnu ja Marko Naissoo" 11. nov. ja Timo Korhoneni kontserdist 18. nov. Vanemuise kontserdisaalis, vanamuusikaansambli Cantores Vagantes kontserdist (külalisesinejaks Fumikata Saito) 12. nov. Tartu Linnamuuseumis ja Tallinna kitarrikvarteti (Heiki Mätlik, Julia Kahro, Kristo Käo, Jorma Puusaag) kontserdist 16. nov. TÜ Ajaloo Muuseumis

Three newly recorded Linyphiid spiders (Araneae: Linyphiidae from Korea

Directory of Open Access Journals (Sweden)

Sue Yeon Lee

2018-03-01

Full Text Available Three Linyphiid spiders, Caviphantes pseudosaxetorum Wunderlich, 1979, Erigone edentata Saito and Ono, 2001, and Savignia kawachiensis Oi, 1960, are reported for the first time from Korea with taxonomic illustrations and redescription. In this study, the genus Caviphantes Oi, 1960 is also newly recorded to Korean spider fauna.

The Potential Sources of Foreign Language Reading Anxiety in a Jordanian EFL Context: A Theoretical Framework

Science.gov (United States)

Ahmad, Ismail Sheikh; Al-Shboul, Murad M.; Nordin, Mohamad Sahari; Rahman, Zainurin Abdul; Burhan, Mohd; Madarsha, Kamal Basha

2013-01-01

The last decade has witnessed an increasing research trend on foreign language reading anxiety as a skill related to but distinct from foreign language anxiety. However, sources of foreign language reading anxiety have rarely been investigated. Thus, the current study responds to the study by (Saito, Horwitz, & Garza, 1999) and extends the…

Implicit-shifted Symmetric QR Singular Value Decomposition of 3x3 Matrices

Science.gov (United States)

2016-04-01

Graph 33, 4, 138:1– 138:11. TREFETHEN, L. N., AND BAU III, D. 1997. Numerical linear algebra , vol. 50. Siam. XU, H., SIN, F., ZHU, Y., AND BARBIČ, J...matrices with minimal branching and elementary floating point operations. Tech. rep., University of Wisconsin- Madison. SAITO, S., ZHOU, Z.-Y., AND

Deja Vu All over Again: A Response to Saito, Horwitz, and Garza.

Science.gov (United States)

Sparks, Richard L.; Ganschow, Leonore; Javorsky, James

2000-01-01

Responds to an earlier article that introduced the concept of foreign language reading anxiety and reported the results of a preliminary study of reading anxiety. Argues that the explanations for the study findings are misguided. (Author/VWL)

Spacecraft Charging Modeling -- Nascap-2k 2014 Annual Report

Science.gov (United States)

2014-09-19

appears to work similarly in Internet Explorer, FireFox , and Opera, but fails in Safari and Chrome. Note that the SEE Spacecraft Charging Handbook is... Characteristics of Spacecraft Charging in Low Earth Orbit, J Geophys Res. 11 7, doi: 10.1029/20 11JA016875, 2012. 2 M. Cho, K. Saito, T. Hamanaga, Data

Problems and approach to geological disposal of radioactive waste

International Nuclear Information System (INIS)

Kitayama, Kazumi; Yamazaki, Haruo; Ijiri, Yuji; Haga, Kazuko; Sakamaki, Masanori; Kishi, Kiyoshi

2006-01-01

This feature articles described a concept and technical problems of geological disposal of high-level radioactive waste in the civil engineering. It consists of six papers such as the present statues and subjects of geological disposal by KITAYAMA Kazumi, the diastrophism, igneous activity, and upheaval and erosion by YAMAZAKI Haruo, the groundwater flow and evaluation of nuclear transfer by IJIRI Yuji, evaluation of alteration of cement materials in the ultra-long period by HAGA Kazuko, The Mizunami Underground Research Laboratory in course of construction by SAKAMAKI Masanori, and interview of the ninetieth president of JSCE (Japan Society of Civil Engineers), he places his hope on JSCE and civil engineers by KISHI Kiyoshi. (S.Y.)

Orthogonality-condition model for bound states with a separable expansion of the potential

International Nuclear Information System (INIS)

Pal, K.F.

1984-01-01

A very efficient solution of the equation of Saito's orthogonality-condition model (OCM) is reported for bound states by means of a separable expansion of the potential (PSE method). Some simplifications of the published formulae of the PSE method is derived, which facilitate its application to the OCM and may be useful in solving the Schroedinger equation as well. (author)

Japanese Studies on Manchuria. Volume 11. Part 3. Book B. Small Wars and Border Problems, The Nomonhan Incident

Science.gov (United States)

1956-09-05

ranks and posts as of the time of the Nomonhan Incident): UaJ. Gen. Yuzaburo Hata, CG, 3d Heavy Field Artillery Brigade MaJ. Gen. Kotoku Sato , CG...111.. 1 II ^72 Col Mikio Sakoi I {X 23 Lt Col Yoozo Azumo _L [j Co 11. . 1 23 Tokahide Ise I I II 23 Isamu Saito fHBCSüJ

Giant piezoelectricity in potassium-sodium niobate lead-free ceramics.

Science.gov (United States)

Wang, Xiaopeng; Wu, Jiagang; Xiao, Dingquan; Zhu, Jianguo; Cheng, Xiaojing; Zheng, Ting; Zhang, Binyu; Lou, Xiaojie; Wang, Xiangjian

2014-02-19

Environment protection and human health concern is the driving force to eliminate the lead from commercial piezoelectric materials. In 2004, Saito et al. [ Saito et al., Nature , 2004 , 432 , 84 . ] developed an alkali niobate-based perovskite solid solution with a peak piezoelectric constant d33 of 416 pC/N when prepared in the textured polycrystalline form, intriguing the enthusiasm of developing high-performance lead-free piezoceramics. Although much attention has been paid on the alkali niobate-based system in the past ten years, no significant breakthrough in its d33 has yet been attained. Here, we report an alkali niobate-based lead-free piezoceramic with the largest d33 of ∼490 pC/N ever reported so far using conventional solid-state method. In addition, this material system also exhibits excellent integrated performance with d33∼390-490 pC/N and TC∼217-304 °C by optimizing the compositions. This giant d33 of the alkali niobate-based lead-free piezoceramics is ascribed to not only the construction of a new rhombohedral-tetragonal phase boundary but also enhanced dielectric and ferroelectric properties. Our finding may pave the way for "lead-free at last".

NATO Guidelines on Human Engineering Testing and Evaluation

Science.gov (United States)

2001-05-01

1980s and is known as Manpower, Personnel, and Training Integration (MANPRINT). The objective of this comprehensive management and technical effort is...systems under benign test conditions, using test subjects who are considerably more knowledeable of the system than the eventual users of the system will...Technical Management , Aeronautical Systems Division, Air Force Systems Command. Itoh, Y., Hayashi, Y., Tsukui, L, and Saito, S. (1989). Heart rate

Addendum: Compliant electrostatic chuck based on hairy microstructure (2013 Smart Mater. Struct. 22 015019) and Electrostatic chuck consisting of polymeric electrostatic inductive fibers for handling of objects with rough surfaces (2013 Smart Mater. Struct. 22 095010)

International Nuclear Information System (INIS)

Saito, Shigeki; Soda, Fumiaki; Sawai, Kenji; Dhelika, Radon; Kikutani, Takeshi; Takarada, Wataru; Takahashi, Kunio

2014-01-01

The recent papers Saito et al 2013 Smart Mater. Struct. 22 015019 and Dhelika et al 2013 Smart Mater. Struct. 22 095010 described studies of an electrostatic chuck that mimics the structure of gecko-like toes. Earlier work published by the authors and other researchers is cited to further illustrate the origin and motivation of the research. (paper)

Heat flow in chains driven by thermal noise

International Nuclear Information System (INIS)

Fogedby, Hans C; Imparato, Alberto

2012-01-01

We consider the large deviation function for a classical harmonic chain composed of N particles driven at the end points by heat reservoirs, first derived in the quantum regime by Saito and Dhar (2007 Phys. Rev. Lett. 99 180601) and in the classical regime by Saito and Dhar (2011 Phys. Rev. E 83 041121) and Kundu et al (2011 J. Stat. Mech. P03007). Within a Langevin description we perform this calculation on the basis of a standard path integral calculation in Fourier space. The cumulant generating function yielding the large deviation function is given in terms of a transmission Green's function and is consistent with the fluctuation theorem. We find a simple expression for the tails of the heat distribution, which turns out to decay exponentially. We, moreover, consider an extension of a single-particle model suggested by Derrida and Brunet (2005 Einstein Aujourd'hui (Les Ulis: EDP Sciences)) and discuss the two-particle case. We also discuss the limit for large N and present a closed expression for the cumulant generating function. Finally, we present a derivation of the fluctuation theorem on the basis of a Fokker–Planck description. This result is not restricted to the harmonic case but is valid for a general interaction potential between the particles

Tendency to adhere to provider-recommended treatments and subsequent pain severity among individuals with cancer

OpenAIRE

Anthony Jerant; Peter Franks; Daniel J Tancredi; et al

2011-01-01

Anthony Jerant1, Peter Franks1, Daniel J Tancredi2, Naomi Saito3, Richard L Kravitz41Department of Family and Community Medicine, Center for Healthcare Policy and Research, University of California Davis School of Medicine, Sacramento, CA, USA; 2Department of Pediatrics, Center for Healthcare Policy and Research, University of California Davis School of Medicine, Sacramento, CA, USA; 3Center for Healthcare Policy and Research, University of California Davis School of Medicine, Sacramento, CA,...

Database Description - Open TG-GATEs Pathological Image Database | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available List Contact us Open TG-GATEs Pathological Image Database Database Description General information of database Database... name Open TG-GATEs Pathological Image Database Alternative name - DOI 10.18908/lsdba.nbdc00954-0...iomedical Innovation 7-6-8, Saito-asagi, Ibaraki-city, Osaka 567-0085, Japan TEL:81-72-641-9826 Email: Database... classification Toxicogenomics Database Organism Taxonomy Name: Rattus norvegi... Article title: Author name(s): Journal: External Links: Original website information Database

Exploratory Analysis of Supply Chains in the Defense Industrial Base

Science.gov (United States)

2012-04-01

hp) 2- and 4- stroke RC/modeler engines are O.S. Engine (Japan), Thunder Tiger (Taiwan), and Saito (Japan). E. Global Nature of the Supply Chain...Mexico). • The 115-HP 4- stroke Rotax 914 class engine (Austria/Germany) found in the Predator (MQ-1B) is also found in many other systems, including...Equipment 43 Pumps and Compressors 44 Furnace/Steam Plant/Drying Equipment, Nuclear Reactors 45 Plumbing, Heating , and Sanitation Equipment 49

A Contribution for the Automatic Sleep Classification Based on the Itakura-Saito Spectral Distance

Science.gov (United States)

Cardoso, Eduardo; Batista, Arnaldo; Rodrigues, Rui; Ortigueira, Manuel; Bárbara, Cristina; Martinho, Cristina; Rato, Raul

Sleep staging is a crucial step before the scoring the sleep apnoea, in subjects that are tested for this condition. These patients undergo a whole night polysomnography recording that includes EEG, EOG, ECG, EMG and respiratory signals. Sleep staging refers to the quantification of its depth. Despite the commercial sleep software being able to stage the sleep, there is a general lack of confidence amongst health practitioners of these machine results. Generally the sleep scoring is done over the visual inspection of the overnight patient EEG recording, which takes the attention of an expert medical practitioner over a couple of hours. This contributes to a waiting list of two years for patients of the Portuguese Health Service. In this work we have used a spectral comparison method called Itakura distance to be able to make a distinction between sleepy and awake epochs in a night EEG recording, therefore automatically doing the staging. We have used the data from 20 patients of Hospital Pulido Valente, which had been previously visually expert scored. Our technique results were promising, in a way that Itakura distance can, by itself, distinguish with a good degree of certainty the N2, N3 and awake states. Pre-processing stages for artefact reduction and baseline removal using Wavelets were applied.

2nd Abel Symposium

CERN Document Server

Nunno, Giulia; Lindstrøm, Tom; Øksendal, Bernt; Zhang, Tusheng

2007-01-01

Kiyosi Ito, the founder of stochastic calculus, is one of the few central figures of the twentieth century mathematics who reshaped the mathematical world. Today stochastic calculus is a central research field with applications in several other mathematical disciplines, for example physics, engineering, biology, economics and finance. The Abel Symposium 2005 was organized as a tribute to the work of Kiyosi Ito on the occasion of his 90th birthday. Distinguished researchers from all over the world were invited to present the newest developments within the exciting and fast growing field of stochastic analysis. The present volume combines both papers from the invited speakers and contributions by the presenting lecturers. A special feature is the Memoirs that Kiyoshi Ito wrote for this occasion. These are valuable pages for both young and established researchers in the field.

Intra-caldera active fault: An example from the Mw 7.0 2016 Kumamoto, Japan, earthquake

Science.gov (United States)

Toda, S.; Murakami, T.; Takahashi, N.

2017-12-01

A NE-trending 30-km-long surface rupture with up to 2.4 m dextral slip emerged during the Mw=7.0 16 April 2016 Kumamoto earthquake along the previously mapped Futagawa and northern Hinagu fault systems. The 5-km-long portion of the northeast rupture end, which was previously unidentified, crossed somma and extended to the 20-km-diameter Aso Caldera, one of the major active volcanoes, central Kyushu. We here explore geologic exposures of interplays of active faulting and active volcanism, and then argue the Futagawa fault system has been influenced by the ring fault system associated with the caldera forming gigantic eruptions since 270 ka, last of which occurred 90 ka ejecting a huge amount of ignimbrite. To understand the interplays, together with the mapping of the 2016 rupture, we employed an UAV to capture numerous photos of the exposures along the canyon and developed 3D orthochromatic topographic model using PhotoScan. One-hundred-meter-deep Kurokawa River canyon by the Aso Caldera rim exposes two lava flow units of 50 ka vertically offset by 10 m by the Futatawa fault system. Reconstructions of the collapsed bridges across the Kurokawa River also reveal cross sections of a 30-meter-high tectonic bulge and 10-m-scale negative flower structure deformed by the frequent fault movements. We speculate two fault developing models across the Aso Caldera. One is that the NE edge of the Futagawa fault system was cut and reset by the caldera forming ring fault, which indicates the 3-km-long rupture extent within the Aso Caldera would be a product of the fault growth since the last Aso-4 eruption of 90 ka. It enables us to estimate the 33 mm/yr of the fault propagation speed. An alternative model is that subsurface rupture of the Kumamoto earthquake extended further to the NE rim, the other side of the caldera edge, which is partially supported by the geodetic and seismic inversions. With respect to the model, the clear surface rupture of the 2016 Kumamoto earthquake

NC-6301, a polymeric micelle rationally optimized for effective release of docetaxel, is potent but is less toxic than native docetaxel in vivo

OpenAIRE

Kano, Mitsunobu; Harada,; Iwata,; Saito,; Ishii,; Hayashi,; Yashiro,; Hirakawa,; Miyazono,Kohei; Kato,Yasuki; Kano,Mitsunobu

2012-01-01

Mitsunori Harada,1 Caname Iwata,2 Hiroyuki Saito,1 Kenta Ishii,1 Tatsuyuki Hayashi,1 Masakazu Yashiro,3 Kosei Hirakawa,3 Kohei Miyazono,2 Yasuki Kato,1 Mitsunobu R Kano21Research Division, NanoCarrier Co, Ltd, Chiba, Japan; 2Department of Molecular Pathology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan; 3Department of Surgical Oncology, Osaka City University, Osaka, JapanAbstract: Drug release rate is an important factor in determining efficacy and toxicity of nanoscale dru...

Laparoscopic intersphincteric resection for low rectal cancer: comparison of stapled and manual coloanal anastomosis.

Science.gov (United States)

Cong, J C; Chen, C S; Ma, M X; Xia, Z X; Liu, D S; Zhang, F Y

2014-05-01

The study aim was to analyse the safety and feasibility of laparoscopic intersphincteric resection with stapled coloanal anastomosis for low rectal cancer. Between March 2009 and August 2010, 22 patients underwent laparoscopic intersphincteric resection with a stapled coloanal anastomosis without a diverting ileostomy. The results were compared retrospectively with hand-sewn coloanal anastomoses performed between January 2001 and May 2009, which included 55 open and 38 laparoscopic intersphincteric resections. The morbidity comparison only included data relevant to the anastomosis. Function was compared using the Saito function questionnaire and the Wexner score and only involved data relevant to the laparoscopy. The anastomotic complication rates were similar for fistula, bleeding and neorectal mucosal prolapse (P = 0.526, P = 0.653 and P = 0.411, respectively). Anastomotic leakage and stricture formation of the stapled coloanal anastomosis were significantly lower than those of the hand-sewn coloanal anastomosis (P = 0.037 and P = 0.028, respectively). There were no significant differences in the Saito function questionnaire and the Wexner score between the stapled and hand-sewn coloanal anastomotic groups (all P > 0.05). Laparoscopic intersphincteric resection with a stapled coloanal anastomosis is technically feasible and is less likely to result in anastomotic leakage and stricture formation than a hand-sewn anastomosis. Colorectal Disease © 2014 The Association of Coloproctology of Great Britain and Ireland.

Integral equations for composite-particle scattering taking the Pauli principle into account

International Nuclear Information System (INIS)

Kukulin, V.I.; Neudatchin, V.G.; Pomerantsev, V.N.

1978-01-01

An approximate description of a system of three composite particles in terms of the Saito (Prog. Theor. Phys.; 41:705 (1969)) orthogonality condition model is proposed. The orthogonalising pseudopotential technique is used to derive a modified set of Fadde'ev equations where the two- and three-body exchanges due to the Pauli principle are included by orthogonalising to two-and three-body forbidden states. The scope of applicability of and the method for solving the derived equations are discussed briefly. (author)

Contribución al conocimiento de la flora de Antioquia / Cinco especies de Piper de Colombia

Directory of Open Access Journals (Sweden)

Daniel Hermano

1940-12-01

Full Text Available EI 15 de septiembre de 1936 tuve oportunidad de visitar el SaIto de Guadalupe, y al día siguiente las poblaciones de Carolina y Gómez Plata. Durante el trayecto hice alguna pequeña colección de plantas; varias de ellas resultaron de positivo interés, ya por Ia novedad científica que presentaron, o ya por haber sido halladas en esta región, relativamente poco explorada por los botánicos.

Bisphosphonates in the Prevention of Post-Traumatic Osteoarthritis

Science.gov (United States)

2016-07-01

osteoarthritis. Am. J. Sports Med. 391 Page 19 of 42 John Wiley & Sons, Inc. Journal of Orthopaedic Research 20 35:1756–1769. 392 2. Anderson DD...Saito M, et al. 2014. Effective knock down of matrix435 metalloproteinase-13 by an intra-articular injection of small interfering RNA (siRNA) in a 436...34. Kawamura S, Lotito K, Rodeo S a. 2003. Biomechanics and healing response of the480 meniscus. Oper. Tech. Sports Med. 11(2):68–76. 481 35. Lerer

A Compendium of Arctic Environmental Information

Science.gov (United States)

1986-03-01

shoulders if it is facing you. Do not try a shot to the head unless you are absolutely sure of a hit . It is better to hit one of the two recommended areas...pp. 29-49, in Japanese. Sater, J. E. (ed.) (1969). The Arctic Basin. Arctic Inst. of North Am., Washington, D.C. Tabata , T., Y. Nohuguchi, and...T. Saito (1980). Observed Sea Ice Thickness in the Northern Okhotsk Sea. Low Temp. Sci. Ser. A, (Japan), n. 39, pp. 153-158. Tabata , Tadashi (1979

Gel Formation in Polymers Undergoing Radiation-Induced Crosslinking and Scission

DEFF Research Database (Denmark)

Handlos, V. N.; Singer, Klaus Albert Julius

1976-01-01

A study was made of the solubility of irradiated polyethylene. The experimental data were treated according to the Saito-Inokuti theory for gel formation in polymers exposed to ionizing radiation. Among other things, this theory is based upon the molecular weight distribution of the unirradiated...... polymer; in the present work, the actual distributions were determined by high-temperature gel permeation chromatography and corrected for long-chain branching. Under these circumstances, good agreement between theory and experimental data was obtained, which allowed the determination of the radiation...

Do Deregulated Cas Proteins Induce Genomic Instability In Early Stage Ovarian Cancer?

Science.gov (United States)

2007-12-01

Tensional homeostasis and the malignant phenotype. Cancer Cell 2005;8:241–54. [PubMed: 16169468] 40. Zhang Z, Hernandez- Lagunas L, Horne WC, Baron R...disassembly. Nat Cell Biol 2004;6:154–61. [PubMed: 14743221] 58. Huang J, Hamasaki H, Nakamoto T, Honda H, Hirai H, Saito M, Takato T, Sakai R...Cell Struct Funct 2001;26:619–26. [PubMed: 11942617] 87. Yi J, Kloeker S, Jensen CC, Bockholt S, Honda H, Hirai H, Beckerle MC. Members of the zyxin

Kurokawa's secret. Or: Why you need lemonade to feed more than 10 kW of solar power into the public grid; Kurokawas Geheimnis. Oder: Warum man in Japan Brause braucht, um mehr als zehn Kilowatt Solarstrom ans Netz zu bringen

Energy Technology Data Exchange (ETDEWEB)

Krause, Matthias B.

2011-05-15

Japan was among the first countries to think about solar power in gigawatt dimensions, but then the country opted increasingly for nuclear power. Now, after the earthquake and tsunami in March and with the ongoing nuclear catastrophe, there appears to be a renaissance of renewable energy sources and especially photovoltaic conversion. To make it happen, the government must take steps and permit competition in the energy market.

International trade and waste and fuel management issue, 2009

Energy Technology Data Exchange (ETDEWEB)

Agnihotri, Newal (ed.)

2009-01-15

The focus of the January-February issue is on international trade and waste and fuel managment. Major articles/reports in this issue include: Innovative financing and workforce planning, by Donna Jacobs, Entergy Nuclear; Nuclear power - a long-term need, by John C. Devine, Gerald Goldsmith and Michael DeLallo, WorleyParsons; Importance of loan guarantee program, by Donald Hintz; EPC contracts for new plants, by Dave Barry, Shaw Power Group; GNEP and fuel recycling, by Alan Hanson, AREVA NC Inc.; Safe and reliable reactor, by Kiyoshi Yamauchi, Mitsubishi Heavy Industries, Ltd.; Safe, small and simple reactors, by Yoshi Sakashita, Toshiba Corporation; Nuclear power in Thailand, by Tatchai Sumitra, Thailand Institute of Nuclear Technology; and, Nuclear power in Vietnam, by Tran Huu Phat, Vietnam Atomic Energy Commission. The Industry Innovation article this issue is Rectifying axial-offset-anomaly problems, by Don Adams, Tennessee Valley Authority. The Plant Profile article is Star of Stars Excellence, by Tyler Lamberts, Entergy Nuclear Operations, Inc.

Noncausal stochastic calculus

CERN Document Server

Ogawa, Shigeyoshi

2017-01-01

This book presents an elementary introduction to the theory of noncausal stochastic calculus that arises as a natural alternative to the standard theory of stochastic calculus founded in 1944 by Professor Kiyoshi Itô. As is generally known, Itô Calculus is essentially based on the "hypothesis of causality", asking random functions to be adapted to a natural filtration generated by Brownian motion or more generally by square integrable martingale. The intention in this book is to establish a stochastic calculus that is free from this "hypothesis of causality". To be more precise, a noncausal theory of stochastic calculus is developed in this book, based on the noncausal integral introduced by the author in 1979. After studying basic properties of the noncausal stochastic integral, various concrete problems of noncausal nature are considered, mostly concerning stochastic functional equations such as SDE, SIE, SPDE, and others, to show not only the necessity of such theory of noncausal stochastic calculus but ...

Analytic function theory of several variables elements of Oka’s coherence

CERN Document Server

Noguchi, Junjiro

2016-01-01

The purpose of this book is to present the classical analytic function theory of several variables as a standard subject in a course of mathematics after learning the elementary materials (sets, general topology, algebra, one complex variable). This includes the essential parts of Grauert–Remmert's two volumes, GL227(236) (Theory of Stein spaces) and GL265 (Coherent analytic sheaves) with a lowering of the level for novice graduate students (here, Grauert's direct image theorem is limited to the case of finite maps). The core of the theory is "Oka's Coherence", found and proved by Kiyoshi Oka. It is indispensable, not only in the study of complex analysis and complex geometry, but also in a large area of modern mathematics. In this book, just after an introductory chapter on holomorphic functions (Chap. 1), we prove Oka's First Coherence Theorem for holomorphic functions in Chap. 2. This defines a unique character of the book compared with other books on this subject, in which the notion of coherence appear...

Learning to Predict Social Influence in Complex Networks

Science.gov (United States)

2012-03-29

nodes remaining inactive, i.e. H = ∅, there is no room for burnout to come in. Thus, we compared the BP with pruning method ( BPP for short) with the...both BPP and naive should give the correct expected influ- ence degree. For a finite value of M, the results may seem different. In fact, as shown in...obtained by using 12 K. Saito et al Table 1. Results for the top 10 nodes v and the values of σ(v, 20) based on the proposed method ( BPP ) for the blog

Approximated treatment of the Pauli principle effects in elastic collisons

International Nuclear Information System (INIS)

Schechter, H.

1984-08-01

Exact microscopic methods like the RGM (Resonanting Group Method) and the GCM (Generator Coordinate Method) and approximate methods like the OCM (Orthogonality Condition Model) are used to study the effects of Pauli Principle in α- 16 O elastic scattering. Using V2 and BL nucleon-nucleon interactions, nucleus-nucleus effective potentials are obtained from RGM 'exact' wave functions and also from an approximate method developed previoulsy. Using these potentials in the OCM Saito Equation phase-shifts are calculated for partial waves Λ = 0, 1, ... 11, in the energy range 0 [pt

Motivações para recompra de ações : uma análise com as empresas da BM&FBovespa e da NYSE

OpenAIRE

Garcia, Inajá Allane Santos

2016-01-01

Este trabalho analisou os motivos determinantes para a recompra de ações realizadas pelas empresas listadas na BM&FBovespa e na NYSE. De acordo com Ikenberry, Lakonishok e Vermaelen (2000) e Gabrielli e Saito (2004), os motivos mais citados pela literatura são: (a) fluxo de caixa livre; (b) sinalização de que as ações estão subavaliadas; (c) distribuição de dividendos; e (d) interesse das empresas em ajustar a estrutura de capital por meio da alavancagem. Devido a isso, optou-se por investiga...

Aislamiento acústico a ruido aéreo en acristalamientos de vidrio

Directory of Open Access Journals (Sweden)

Escuder Silla, E.

2007-08-01

Full Text Available In this paper, the Ookura & Saito model is applied to determine the Airborne Sound Insulation of glazing systems. In particular, the calculations that appear are for monolithic glasses of different thicknesses and laminated glasses from different types. There are different prediction models of the airborne acoustic behaviour of multilayer panels (and the laminated glasses can be considered like such. In all of them, the input data are the elastic constants and the loss factor. The monolithic glasses and the intermediate layer have been characterized according to different Standards. The results are compared with experimental measurements and data of the study of Marsh (1, obtaining a range of acceptable adjustment.

En este artículo se aplica el modelo de Ookura & Saito para determinar el aislamiento acústico a ruido aéreo de sistemas constructivos basados en vidrios. En concreto, los cálculos que se presentan son para vidrios monolíticos de distintos espesores y para vidrios laminados de diferentes tipos. Existen diferentes modelos de predicción del comportamiento acústico a ruido aéreo de estructuras multicapa (y los vidrios laminados pueden considerarse como tales. En todos ellos, los datos de entrada son las constantes elásticas y el factor de pérdidas. Tanto los vidrios monolíticos como la capa intermedia se han caracterizado siguiendo diferentes normativas. Los resultados se comparan con medidas experimentales y con datos recogidos del estudio de Marsh (1, obteniéndose un grado de ajuste aceptable.

Industrious peasants in east and west: markets, technology, and family structure in Japanese and Western European agriculture.

Science.gov (United States)

De Vries, Jan

2011-01-01

Jan de Vries engages with Osamu Saito's discussion of Tokugawa Japan, in particular, his exploration of de Vries's concept of an industrious revolution for East Asia, which was published in this journal in 2010. The discussion bears on the ongoing debate over the timing and character of the Great Divergence, when advanced parts of Europe pulled ahead of Asia. de Vries argues that the constraint on the Japanese rural household to acquire and shed labour delayed the shift from supply-side industriousness to demand-motivated industriousness, which in turn meant that the Great Divergence was already in place before 1800.

Feasibility study for international collaboration on photovoltaic power generation and long-distance energy transmission technologies utilizing desert areas environment; Sabaku chiiki wo riyoshita taiyoko hatsuden chokyori yuso gijutsu ni kakawaru kokusai kyoryoku kanosei chosa

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-03-01

A workshop was held at Tokyo in March, 1997 on the research and development and feasibility study for international collaboration on photovoltaic (PV) power generation and long-distance energy transmission technologies utilizing desert areas environment. Two speakers from the USA, one from Italy, and two from China were invited, and four speakers in Japan presented papers. A total of 48 persons participated. In the technical sessions, `World energy demand and PV system potential` by Prof. Kurokawa, `Long distance transmission of PV power` by Mr. A. Invenizzi, `Case studies of large scale PV systems distributed throughout desert areas of the world` by Mr. Hirasawa, `Linking renewable energy resources around the world` by Mr. P. Meisen, `Properties of large scale PV plant in the USA` by Mr. J. Benner, `Future prospect of PV electrification in China` by Mr. Kong Li, `Application of large-scale PV systems in deserts in China` by Mr. Isomura, and `Effects of large-scale PV power plant in a climatic desert areas` by Prof. Ihara were presented. 38 refs., 62 figs., 29 tabs.

Sea-level rise caused by climate change and its implications for society.

Science.gov (United States)

Mimura, Nobuo

2013-01-01

Sea-level rise is a major effect of climate change. It has drawn international attention, because higher sea levels in the future would cause serious impacts in various parts of the world. There are questions associated with sea-level rise which science needs to answer. To what extent did climate change contribute to sea-level rise in the past? How much will global mean sea level increase in the future? How serious are the impacts of the anticipated sea-level rise likely to be, and can human society respond to them? This paper aims to answer these questions through a comprehensive review of the relevant literature. First, the present status of observed sea-level rise, analyses of its causes, and future projections are summarized. Then the impacts are examined along with other consequences of climate change, from both global and Japanese perspectives. Finally, responses to adverse impacts will be discussed in order to clarify the implications of the sea-level rise issue for human society.(Communicated by Kiyoshi HORIKAWA, M.J.A.).

Stemcell Information: SKIP000797 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available pe II (ACG2) ... 200610 ... Fetus Female ... Yes No ACG II(GM07892)-specific iPS cells 軟骨無発症患者線維芽細胞(GM07892)由来iPS細胞...PS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 ... Information Only Center for iPS Cell Res...earch and Application,Kyoto University 京都大学iPS細胞研究所　CiRA https://www.cira.kyoto-u.ac.jp/e/index.html ... 251...irected conversion and induced pluripotent stem cells. Okada M, Ikegawa S, Morioka M, Yamashita A, Saito A,

Stemcell Information: SKIP001099 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available line derived from a neonate.(789013 KURABO)| 新生児皮膚繊維芽細胞(789013 KURABO)由来iPS細胞 human ES-like Res...ication, Kyoto University 京都大学iPS細胞研究所 ... Information Only Center for iPS Cell Research and Application,Kyoto University 京都大学iPS細胞... SKIP001099 ... Normal WT-2-#32 WT-2-#32 ... 0-9 Male ... -- No Nomal human iPS cell... Modeling type II collagenopathy skeletal dysplasia by directed conversion and in...duced pluripotent stem cells. Okada M, Ikegawa S, Morioka M, Yamashita A, Saito A, Sawai H, Murotsuki J, Oha

arXiv On Matrix Factorizations, Residue Pairings and Homological Mirror Symmetry

CERN Document Server

Lerche, Wolfgang

We argue how boundary B-type Landau-Ginzburg models based on matrix factorizations can be used to compute exact superpotentials for intersecting D-brane configurations on compact Calabi-Yau spaces. In this paper, we consider the dependence of open-string, boundary changing correlators on bulk moduli. This determines, via mirror symmetry, non-trivial disk instanton corrections in the A-model. As crucial ingredient we propose a differential equation that involves matrix analogs of Saito's higher residue pairings. As example, we compute from this for the elliptic curve certain quantum products m_2 and m_3, which reproduce genuine boundary changing, open Gromov-Witten invariants.

Pseudo-potential method for taking into account the Pauli principle in cluster systems

International Nuclear Information System (INIS)

Krasnopol'skii, V.M.; Kukulin, V.I.

1975-01-01

In order to take account of the Pauli principle in cluster systems (such as 3α, α + α + n) a convenient method of renormalization of the cluster-cluster deep attractive potentials with forbidden states is suggested. The renormalization consists of adding projectors upon the occupied states with an infinite coupling constant to the initial deep potential which means that we pass to pseudo-potentials. The pseudo-potential approach in projecting upon the noneigenstates is shown to be equivalent to the orthogonality condition model of Saito et al. The orthogonality of the many-particle wave function to the forbidden states of each two-cluster sub-system is clearly demonstrated

Stemcell Information: SKIP000798 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available II (ACG2) ... 200610 ... Fetus Female ... Yes No ACG II(GM07892)-specific iPS cells 軟骨無発生症患者線維芽細胞(GM07892)由来iPS細胞...S Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 ... Information Only Center for iPS Cell Rese...arch and Application,Kyoto University 京都大学iPS細胞研究所　CiRA https://www.cira.kyoto-u.ac.jp/e/index.html ... 2518...rected conversion and induced pluripotent stem cells. Okada M, Ikegawa S, Morioka M, Yamashita A, Saito A, S

Stemcell Information: SKIP001098 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available line derived from a neonate.(789013 KURABO)| 新生児皮膚繊維芽細胞(789013 KURABO)由来iPS細胞 human ES-like Res...ication, Kyoto University 京都大学iPS細胞研究所 ... Information Only Center for iPS Cell Research and Application,Kyoto University 京都大学iPS細胞... SKIP001098 ... Normal WT-2-#31 WT-2-#31 ... 0-9 Male ... -- No Nomal human iPS cell... Modeling type II collagenopathy skeletal dysplasia by directed conversion and in...duced pluripotent stem cells. Okada M, Ikegawa S, Morioka M, Yamashita A, Saito A, Sawai H, Murotsuki J, Oha

Stemcell Information: SKIP001100 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available line derived from a neonate.(789013 KURABO)| 新生児皮膚繊維芽細胞(789013 KURABO)由来iPS細胞 human ES-like Res...ication, Kyoto University 京都大学iPS細胞研究所 ... Information Only Center for iPS Cell Research and Application,Kyoto University 京都大学iPS細胞... SKIP001100 ... Normal WT-2-#33 WT-2-#33 ... 0-9 Male ... -- No Nomal human iPS cell... Modeling type II collagenopathy skeletal dysplasia by directed conversion and in...duced pluripotent stem cells. Okada M, Ikegawa S, Morioka M, Yamashita A, Saito A, Sawai H, Murotsuki J, Oha

Report on achievements in fiscal 1999. Development of technology to put photovoltaic power generation system into practical use by international cooperation project (Executive Committee meetings for treaty of executing IEA photovoltaic power generation system research cooperation program - IEA/PVPS); 1999 nendo taiyoko hatsuden system jitsuyoka gijutsu kaihatsu. Kokusai kyoryoku jigyo (IEA taiyoko hatsuden system kenkyu kyoryoku program jisshi kyotei (shikko iinkai))

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-03-01

The 13th and 14th Executive Committee meetings were held. The resolutions adopted at the 13th Executive Committee meeting (Lausanne, Switzerland, May 3 through 5, 1999) were the approval of the Task VIII as a new IEA/PVPS task, the feasibility study on large scale photovoltaic power generation utilizing unused land such as desert (the operating agent country being Japan headed by Mr. Kando, chief researcher at NEDO and Professor Kurokawa) and the Task IX, proliferation of photovoltaic power generation under coordination with developing countries (the operating agent country being England headed by Mr. Bernard McNelis (IT Power) and that the task I operating agent country is substituted jointly by the three countries of Australia, Holland and Switzerland for six months. The resolutions adopted at the 14th Executive Committee meeting (Oslo, Norway, October 18 through 20, 1999) were appointing Australia as the Task I operating agent country headed by Mr. G. Watt, setting a web site of IEA/PVPS, issuing the annual report for fiscal 1998 in early 2000, and holding the Executive Committee meetings for fiscal 2000 in Canada (Quebec, April 17 through 19, 2000), and Italy (October 16 through 18, 2000). (NEDO)

Clinical and histological evaluation of large macular hole surgery using the inverted internal limiting membrane flap technique

Directory of Open Access Journals (Sweden)

Kase S

2016-12-01

Full Text Available Satoru Kase, Wataru Saito, Shohei Mori, Michiyuki Saito, Ryo Ando, Zhenyu Dong, Tomohiro Suzuki, Kousuke Noda, Susumu Ishida Department of Ophthalmology, Hokkaido University Graduate School of Medicine, Sapporo, Japan Purpose: The aims of this study were to analyze optical coherence tomography (OCT imaging of large macular holes (MHs treated with inverted internal limiting membrane (ILM flap technique and to perform a histological examination of an ILM-like membrane tissue obtained during vitrectomy.Patients and methods: This is a retrospective observational case study. Nine patients, comprising of five males and four females, showing large and myopic MHs, underwent pars plana vitrectomy (PPV with inverted ILM flap technique assisted by brilliant blue G (BBG staining. Ophthalmological findings including visual acuity and OCT were investigated based on medical records. Formalin-fixed paraffin-embedded tissue section of an ILM-like membrane was submitted for immunohistochemistry with glial fibrillary acidic protein (GFAP.Results: ILM was clearly stained with BBG in eight patients, whereas the ILM in one case revealed no staining with BBG during PPV. Visual acuities improved to >0.2 LogMAR in six patients. The complete closure of MH following PPV with inverted ILM technique was eventually achieved in all patients determined by OCT imaging (100%. Only one patient showed recovery of ellipsoid zone and interdigitation zone following the surgery. Elongation of outer nuclear layer was noted in three eyes. The ILM-like membrane not stained with BBG histologically revealed an amorphous structure admixed with GFAP-positive mononuclear cell infiltration.Conclusion: PPV with inverted ILM flap technique achieved 100% closure rates with favorable configuration at an initial surgery in large MHs. Our histopathological data also suggest that even BBG staining-negative membrane may be a useful material for autologous transplantation to the hole. Keywords

Stemcell Information: SKIP000802 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available pe II (ACG2) ... 200610 ... 0-9 Male ... Yes No ACG II(S2011-46)-specific iPS cells. Ⅱ型コラーゲン異常症患者線維芽細胞(S2011-46)由来iPS細胞...or iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 ... Information Only Center for iPS Cell... Research and Application,Kyoto University 京都大学iPS細胞研究所　CiRA https://www.cira.kyoto-u.ac.jp/e/index.html ... ...by directed conversion and induced pluripotent stem cells. Okada M, Ikegawa S, Morioka M, Yamashita A, Saito

Mixed twistor D-modules

CERN Document Server

Mochizuki, Takuro

2015-01-01

We introduce mixed twistor D-modules and establish their fundamental functorial properties. We also prove that they can be described as the gluing of admissible variations of mixed twistor structures. In a sense, mixed twistor D-modules can be regarded as a twistor version of M. Saito's mixed Hodge modules. Alternatively, they can be viewed as a mixed version of the pure twistor D-modules studied by C. Sabbah and the author. The theory of mixed twistor D-modules is one of the ultimate goals in the study suggested by Simpson's Meta Theorem, and it would form a foundation for the Hodge theory of holonomic D-modules which are not necessarily regular singular.  .

A Brief History of Shigella.

Science.gov (United States)

Lampel, Keith A; Formal, Samuel B; Maurelli, Anthony T

2018-01-01

The history of Shigella , the causative agent of bacillary dysentery, is a long and fascinating one. This brief historical account starts with descriptions of the disease and its impact on human health from ancient time to the present. Our story of the bacterium starts just before the identification of the dysentery bacillus by Kiyoshi Shiga in 1898 and follows the scientific discoveries and principal scientists who contributed to the elucidation of Shigella pathogenesis in the first 100 years. Over the past century, Shigella has proved to be an outstanding model of an invasive bacterial pathogen and has served as a paradigm for the study of other bacterial pathogens. In addition to invasion of epithelial cells, some of those shared virulence traits include toxin production, multiple-antibiotic resistance, virulence genes encoded on plasmids and bacteriophages, global regulation of virulence genes, pathogenicity islands, intracellular motility, remodeling of host cytoskeleton, inflammation/polymorphonuclear leukocyte signaling, apoptosis induction/inhibition, and "black holes" and antivirulence genes. While there is still much to learn from studying Shigella pathogenesis, what we have learned so far has also contributed greatly to our broader understanding of bacterial pathogenesis.

A NOVEL APPROACH TO STUTTERED SPEECH CORRECTION

Directory of Open Access Journals (Sweden)

Alim Sabur Ajibola

2016-06-01

Full Text Available Stuttered speech is a dysfluency rich speech, more prevalent in males than females. It has been associated with insufficient air pressure or poor articulation, even though the root causes are more complex. The primary features include prolonged speech and repetitive speech, while some of its secondary features include, anxiety, fear, and shame. This study used LPC analysis and synthesis algorithms to reconstruct the stuttered speech. The results were evaluated using cepstral distance, Itakura-Saito distance, mean square error, and likelihood ratio. These measures implied perfect speech reconstruction quality. ASR was used for further testing, and the results showed that all the reconstructed speech samples were perfectly recognized while only three samples of the original speech were perfectly recognized.

Characterization of the degree of cross-linking in radiation cross-linked low and high density polyethylenes

International Nuclear Information System (INIS)

Posselt, K.; Haedrich, W.

1986-01-01

In practice the cross-linking of irradiated polyethylene is mostly characterized by solubility and thermomechanical data. The irradiation of samples of a LDPE and a HDPE yields very different gel-dose curves. But for a quantitative comparison the complicated connection between the gel values and the corresponding densities of cross-links, especially the dependence on the initial molecular size distribution, has to take into consideration. The analysis of the solubility data according to the statistical theory of cross-linking developed by Inokuti and Saito shows that at equal doses in both investigated PE types in spite of the different gel values nearly the same densities of cross-links are present. That result is confirmed by the densities of cross-links determined from stress-strain measurements at 423 K. (author)

Observation of dynamic interactions between fundamental and second-harmonic modes in a high-power sub-terahertz gyrotron operating in regimes of soft and hard self-excitation.

Science.gov (United States)

Saito, Teruo; Tatematsu, Yoshinori; Yamaguchi, Yuusuke; Ikeuchi, Shinji; Ogasawara, Shinya; Yamada, Naoki; Ikeda, Ryosuke; Ogawa, Isamu; Idehara, Toshitaka

2012-10-12

Dynamic mode interaction between fundamental and second-harmonic modes has been observed in high-power sub-terahertz gyrotrons [T. Notake et al., Phys. Rev. Lett. 103, 225002 (2009); T. Saito et al. Phys. Plasmas 19, 063106 (2012)]. Interaction takes place between a parasitic fundamental or first-harmonic (FH) mode and an operating second-harmonic (SH) mode, as well as among SH modes. In particular, nonlinear excitation of the parasitic FH mode in the hard self-excitation regime with assistance of a SH mode in the soft self-excitation regime was clearly observed. Moreover, both cases of stable two-mode oscillation and oscillation of the FH mode only were observed. These observations and theoretical analyses of the dynamic behavior of the mode interaction verify the nonlinear hard self-excitation of the FH mode.

[Bone Cell Biology Assessed by Microscopic Approach. The effects of active vitamin D3 such as alfacalcidol and eldecalcitol on bone quality].

Science.gov (United States)

Saito, Mitsuru; Marumo, Keishi

2015-10-01

Active vitamin D3 is used for the treatment for osteoporosis in Japan. Recently, data have accumulated that collagen cross-link formation in bone affect bone strength. In fact, impaired enzymatic cross-linking, over-hydroxylation of crosslinks, and an increase in non-enzymatic crosslinking advanced glycation end products (AGEs) such as pentosidine, in bone collagen have been proposed as a major cause of bone fragility in osteoporosis. We reported that alfacalcidol and eldecalcitol improves bone material properties such as collagen cross-link formation, microarchitecture, and microcrack resulting in the increase of bone strength (Saito M, Bone 2010;46:1170-1179, Calcif Tissue Int 2011;88:314-324, Bone, 2015;73:8-15). In this review, we described how active vitamin D3 improve bone collagen cross-link formation and mineral qualities.

Shiga Toxin in Enterohemorrhagic E.coli: regulation and novel antivirulence strategies

Directory of Open Access Journals (Sweden)

Vanessa eSperandio

2012-06-01

Full Text Available Enterohemorrhagic Escherichia coli O157:H7 infects about 73,000 people annually in the USA and is a major cause of outbreaks of bloody diarrhea worldwide, and. In 5 to 7% of the cases, the person infected develops the potentially fatal sequelae hemolytic uremic syndrome (HUS, characterized by acute kidney failure. A hallmark of EHEC pathogenesis and cause of HUS is the production of Shiga toxin (Stx. Stx was first described by Kiyoshi Shiga in Shigella dysenterae serotype I and later discovered in EHEC, and it has been linked to HUS since 1983. Many factors regulate the production of Stx, including temperature, growth phase, antibiotics, reactive oxygen species and quorum sensing. Currently, there is no effective treatment or prophylaxis for HUS. Since the use of antibiotics is not advised to treat EHEC infections because it triggers Stx production, alternative antibacterial strategies need to be developed. Quorum sensing inhibitors represent a novel class of antibacterial compounds, which have the advantage of not interfering on bacterial growth, thereby without selective pressure that can lead to appearance of resistant strains. In this review, we discuss factors that regulate Stx production in EHEC as well as novel strategies to fight Stx and minimize development to HUS in EHEC-infected patients.

Quantitative RI cisternography in hydrocephalus

International Nuclear Information System (INIS)

Hara, Masao; Kayamori, Ryo; Sato, Kazuaki; Miyazawa, N.

1975-01-01

Ventriculography and cisterography with 131 I-HSA, and 167 Yb-DTPA were performed in patients with obstructive and normal-pressure hydrocephalus. Radioactivity in the head, blood counts and excretions in the urine were determined. In the patients with obstructive hydrocephalus, the radioactivity reduction in the head was late by the ventricular injection, while it was normal by the lumbar puncture. In the patients with normal-pressure hydrocephalus, the radioactivity reduction curve varied both by the ventricular injection and the lumbar puncture. However, these did not indicate the results of the shunt operation. The external determination of the rate of reduction of radioactivity in the head were parallel with blood radioactivity the urinary excretion rate. In the patients with normal-pressure hydrocephalus, the absorption rate of the spinal fluid decreased independently from the radioactivity curve in the head. (Saito, K.)

Proglobulin processing enzyme in vacuoles isolated from developing pumpkin cotyledons

International Nuclear Information System (INIS)

Hara-Nishimura, I.; Nishimura, M.

1987-01-01

The enzymic conversion of proglobulin to globulin catalyzed by the extracts of vacuoles isolated from developing pumpkin (Cucurbita sp. cv Kurokawa Amakuri Nankin) cotyledons was investigated. The endoplasmic reticulum fraction isolated from the developing cotyledons pulse-labeled with [ 35 S]methionine was shown to contain mainly the radiolabeled proglobulin, which was used as a substrate for assaying the proteolytic processing in vitro. The vacuolar extracts catalyzed the proteolytic processing of the proglobulin molecule to produce globulin containing two kinds of polypeptide chains, γ and δ. The pH optimum for the vacuole-mediated conversion was at pH 5.0. The proteolytic processing of proglobulin by the vacuolar extracts was inhibited in the presence of various thiol reagents, e.g. p-chloromercuribenzoate, N-ethylmaleimide, iodoacetic acid, Hg 2+ , and Cu 2+ , but not phenylmethylsulfonyl fluoride, EDTA, o-phenanthroline, leupeptin, antipain, pepstatin, chymostatin, or pumpkin trypsin inhibitor, and was activated in the presence of dithiothreitol and cysteine, indicating that the processing enzyme is a thiol protease. The suborganellar fractionation of the vacuoles showed that the processing activity was localized in the matrix fraction, but not in the membrane or crystalloid fractions. During the seed development, the enzyme was shown to increase, exhibiting the maximal activity at the late developmental stage. The matrix fraction of the protein bodies isolated from the dry castor bean (Ricinus communis) exhibited the processing activity toward the pumpkin proglobulin molecules in the same manner as that by the matrix fraction of pumpkin vacuoles

Dynamic Monte Carlo rate constants for magnetic Hamiltonians coupled to a phonon bath

Science.gov (United States)

Solomon, Lazarus; Novotny, Mark

2007-03-01

For quantitative comparisons between experimental time- dependent measurements and dynamic Monte Carlo simulations, a relation between the time constant in the simulation and real time is necessary. We calculate the transition rate for spin S system using the lattice frame method for a rigid spin cluster in an elastic medium [1]. We compare this with the transition rate for an Ising spin 12 system using the quantum- mechanical density-matrix method [2] with the results of ref [1,3]. These transition probabilities are different from those of either the Glauber or the Metropolis dynamics, and reflect the properties of the bosonic bath. Comparison with recent experiments [4] will be discussed. [1] E. M. Chudnovsky, D. A. Garanin, and R. Schilling (PRB 72, 2006) [2] K. Park, M. A. Novotny, and P. A. Rikvold (PRE 66, 2002) [3] K Saito, S. Takesue, and S. Miyashita, (PRE 61, 2002) [4] T. Meunier et al (Condensed Matter, 2006)

Lead-free piezoelectrics based on potassium-sodium niobate with giant d(33).

Science.gov (United States)

Zhang, Binyu; Wu, Jiagang; Cheng, Xiaojing; Wang, Xiaopeng; Xiao, Dingquan; Zhu, Jianguo; Wang, Xiangjian; Lou, Xiaojie

2013-08-28

High-performance lead-free piezoelectrics (d33 > 400 pC/N) based on 0.96(K0.5Na0.5)0.95Li0.05Nb1-xSbxO3-0.04BaZrO3 with the rhombohedral-tetragonal (R-T) phase boundary have been designed and prepared. The R-T phase boundary lies the composition range of 0.04 ≤ x ≤ 0.07, and the dielectric and piezoelectric properties of the ceramics with the compositions near the phase boundary are significantly enhanced. In addition, the ceramic with x = 0.07 has a giant d33 of ~425 pC/N, which is comparable to that (~416 pC/N) of textured KNN-based ceramics (Saito, Y.; Takao, H.; Tani, T.; Nonoyama, T.; Takatori, K.; Homma, T.; Nagaya, T.; Nakamura, M. Nature 2004, 432, 84). The underlying physical mechanisms for enhanced piezoelectric properties are addressed. We believe that the material system is the most promising lead-free piezoelectric candidates for the practical applications.

COPD is frequent in conditions of comorbidity in patients treated with various diseases in a university hospital

Directory of Open Access Journals (Sweden)

Akira Yamasaki

2010-09-01

Full Text Available Akira Yamasaki, Kiyoshi Hashimoto, Yasuyuki Hasegawa, Ryota Okazaki, Miki Yamamura, Tomoya Harada, Shizuka Ito, Soichiro Ishikawa, Hiroki Takami, Masanari Watanabe, Tadashi Igishi, Yuji Kawasaki, Eiji ShimizuDivision of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University, JapanBackground: Chronic obstructive pulmonary disease (COPD is one of the leading causes of death and loss of disability-adjusted life-years. However, many COPD patients are not diagnosed because of underrecognition or underdiagnosis of this disease among many patients and physicians. One possible reason is underrecognition of spirometry. In this study, we examined the prevalence of airflow limitation and underlying disease in patients with airflow limitation.Methodology: From April 2006 to March 2008, patients who had spirometry performed were examined. The original disease of patients, pulmonary function tests, smoking status, and respiratory symptoms were surveyed from their medical records.Results: Of all patients who had spirometry performed, 15.8% showed airflow limitation (FEV1/FVC < 0.7. A variety of diseases were observed in patients with airflow limitation. Among all diseases, cardiovascular disease was the highest and gastrointestinal malignant disease had the second highest prevalence in patients with airflow limitation.Conclusion: COPD might be frequent in conditions of comorbidity in patients treated for various diseases. Attention should be paid to the possibility of co-existence of COPD and the influence of COPD on these patients.Keywords: airflow limitation, chronic obstructive pulmonary disease, comorbidity, spirometry, prevalence

Evaluation of the Systematic Status of Geographical Variations in Arcuphantes hibanus (Arachnida: Araneae: Linyphiidae), with Descriptions of Two New Species.

Science.gov (United States)

Nakano, Takafumi; Ihara, Yoh; Kumasaki, Yusuke; Baba, Yuki G; Tomikawa, Ko

2017-08-01

The systematic status of geographical variants of Arcuphantes hibanus Saito, 1992 belonging to the A. longiscapus species group, indigenous to western Honshu and Shikoku, Japan, was evaluated using morphological and molecular data. Two species, A. enmusubi Ihara, Nakano and Tomikawa, sp. nov. and A. occidentalis Ihara, Nakano and Tomikawa, sp. nov., are described, and A. hibanus is redescribed with redefinition of its taxonomic status. These three species are diagnosed by the characteristics of paracymbium, pseudolamella, and epigynal basal part. Phylogenetic trees obtained with mitochondrial cytochrome c oxidase subunit I and 16S rRNA markers showed that the variants are mutually genetically highly diverged. However, the mtDNA phylogenies failed to recover the monophyly of A. hibanus redefined herein. Contrary to the mtDNA phylogenetic analyses, a neighbor-network analysis of nuclear internal transcribed spacer 1 sequences of A. hibanus, A. enmusubi and A. occidentalis spiders showed that each of them forms a cluster. The results of mitochondrial and nuclear DNA analyses in each of the three species are briefly discussed, along with their taxonomic identities.

Two new species and new records of Microprosthema Stimpson, 1860 (Crustacea: Decapoda: Stenopodidea: Spongicolidae) from the Indo-West Pacific.

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Saito, Tomomi; Anker, Arthur

2014-08-28

Two new species of the spongicolid shrimp genus Microprosthema Stimpson, 1860 are described and illustrated on the basis of material collected recently in Australia and Japan. Type specimens of Microprosthema ningaloo sp. nov. were collected on Ningaloo Reef, Western Australia, whereas type specimens of Microprosthema pallidum sp. nov. were collected on a coral reef off Ishigaki Island, Ryukyu Archipelago, southern Japan. Microprosthema ningaloo sp. nov. and M. pallidum sp. nov. differ from all other species of the genus by a combination of morphological characters, including the gill-exopod formulae, and by their diagnostic colour patterns. This study increases the total number of species described in the genus Microprosthema to 16, nine of them in the Indo-West Pacific. In addition, new records are provided for M. lubricum Saito & Okuno, 2011 (Guam), M. plumicorne (Richters, 1880) (Red Sea, Mariana and Marshall Islands, French Polynesia), M. scabricaudatum (Richters, 1880) (Red Sea, Glorieuses and Tuamotu Islands), and M. validum Stimpson, 1860 (Red Sea, Madagascar, Singapore, French Polynesia), significantly extending their previously known distribution ranges. 

[Investigating phonological planning processes in speech production through a speech-error induction technique].

Science.gov (United States)

Nakayama, Masataka; Saito, Satoru

2015-08-01

The present study investigated principles of phonological planning, a common serial ordering mechanism for speech production and phonological short-term memory. Nakayama and Saito (2014) have investigated the principles by using a speech-error induction technique, in which participants were exposed to an auditory distracIor word immediately before an utterance of a target word. They demonstrated within-word adjacent mora exchanges and serial position effects on error rates. These findings support, respectively, the temporal distance and the edge principles at a within-word level. As this previous study induced errors using word distractors created by exchanging adjacent morae in the target words, it is possible that the speech errors are expressions of lexical intrusions reflecting interactive activation of phonological and lexical/semantic representations. To eliminate this possibility, the present study used nonword distractors that had no lexical or semantic representations. This approach successfully replicated the error patterns identified in the abovementioned study, further confirming that the temporal distance and edge principles are organizing precepts in phonological planning.

2nd Industry-Academia Research Exchange Conference. Research report for fiscal 1992; Dai 2 kai sangaku kenkyu koryukai. 1992 nendo kenkyu hokoku

Energy Technology Data Exchange (ETDEWEB)

NONE

1993-06-24

The above-named conference was convened on June 24, 1993, hosted by the Photovoltaic Power Generation Technology Research Association. The research achievement reports made at the event were 'Thermodynamic evaluation of boron in silicon' by Professor Sano of Tokyo University, 'Solar cell system payback time' by Professor Komiyama of Tokyo University, 'Delta-doped amorphous silicon solar cell' by Professor Konagai of Tokyo Institute of Technology, 'Interaction of silicon thin film and atom-state hydrogen' by Professor Shimizu of Tokyo Institute of Technology, 'Simulation of solar module characteristics' by Professor Saito of Tokyo University of Agriculture and Technology, 'Manufacture of CuInSe{sub 2} thin film for solar cell' by Professor Kunioka of Aoyama Gakuin University, 'Solar cell material/process characterization by use of photoluminescence surface state spectroscopy' by Professor Hasegawa of Hokkaido University, 'Research on tandem solar cell using compound-on-silicon semiconductor crystal' by Professor Umeno of Nagoya University, and 'Efficiency improvement in amorphous Si/polycrystalline Si tandem solar cell' by Professor Hamakawa of Osaka University. (NEDO)

Experiments and analyses on melt jet impingement during severe accidents

International Nuclear Information System (INIS)

Sehgal, B.R.; Green, J.A.; Dinh, T.N.; Dong, W.

1997-01-01

Relocation of melt from the core region, during a nuclear reactor severe accident, presents the potential for erosion of the reactor pressure vessel (RPV) wall as a result of melt jet impingement. The extent of vessel erosion will depend upon a variety of parameters, including jet diameter, velocity, composition, superheat, angle of inclination, and the presence of an overlying water or melt pool. Experiments have been conducted at the Royal Institute of Technology Division of Nuclear Power Safety (RIT/NPS) which employ a variety of melt and pressure vessel simulant materials, such as water, salt-ice, Cerrobend alloy and molten salt. These experiments have revealed that the erosion depth of the vessel simulant in the jet stagnation zone can be adequately predicted by the Saito correlation, which is based on turbulent heat transfer, while initial erosion rates are seen to be in line with the laminar-stagnation-zone model. A transition between the laminar and turbulent regimes was realized in most cases and is attributed to the roughness of the surface in the eroded cavity formed

Cyclo-octafluorobutane (PFC-318) in the global atmosphere

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Muhle, J.; Vollmer, M. K.; Fraser, P. J.; Rhee, T. S.; Ivy, D. J.; Arnold, T.; Harth, C. M.; Salameh, P.; O'Doherty, S.; Young, D.; Steele, P.; Krummel, P. B.; Leist, M.; Schmidbauer, N.; Lunder, C.; Kim, J.; Kim, K.; Reimann, S.; Simmonds, P.; Prinn, R. G.; Weiss, R. F.

2010-12-01

PFC-318 (c-C4F8, cyclo-octafluorobutane) is a long-lived (3200 years) perfluorocarbon (PFC) greenhouse gas with a high 100-year Global Warming Potential (GWP100 = 10,300) and a wide range of industrial uses. We extend previous atmospheric measurements of PFC-318 in the Cape Grim Air Archive (Oram, 1999) with our new in situ measurements from remote and urban AGAGE (Advanced Global Atmospheric Gases Experiment) and affiliated stations. Our longest in situ record is from the Jungfraujoch observatory in the Swiss Alps, and our data set is augmented by measurements of flasks from the King Sejong and Troll coastal Antarctic stations and several locations in the Northern Hemisphere. In mid-2009 we find ˜1.25 ppt (parts-per-trillion, dry mol fraction) in the Northern Hemisphere and ˜1.20 ppt in the Southern Hemisphere, with rise rates of ˜0.03 ppt/yr and an interhemispheric ratio of ˜1.04. We obtain PFC-318 emissions for 2008-2010 of ˜1 Gg/yr using a simple box model, and preliminary measurements of older archived air at SIO indicate similar emissions since at the least the late 1990s. In contrast, the EDGAR v4 emissions database estimates much lower PFC-318 emissions of 0.02 Gg/yr for 2005. Using GWP100 we calculate ˜10 million tons of CO2-equivalent PFC-318 emissions/yr for 2008-2010, about double the CO2-equivalent PFC-218 annual emissions, or 0.4 times the CO2-equivalent PFC-116 annual emissions, reported for 2008-2009 by Mühle et al. (2010). Thus PFC-318 is the third most important PFC in terms of CO2-equivalent emissions. We find mostly baseline conditions at remote AGAGE stations and urban sites in the USA, Europe, and Australia, in contrast to frequent above baseline conditions at Gosan station, Jeju Island, South Korea, indicating significant emission sources in East Asia as found by Saito et al. (2010). Oram, D.E., Trends of long-lived anthropogenic halocarbons in the Southern Hemisphere and model calculation of global emissions, Ph.D. thesis, University

A data processing method for determining instantaneous angular speed and acceleration of crankshaft in an aircraft engine-propeller system using a magnetic encoder

Science.gov (United States)

Yu, S. D.; Zhang, X.

2010-05-01

This paper presents a method for determining the instantaneous angular speed and instantaneous angular acceleration of the crankshaft in a reciprocating engine and propeller dynamical system from electrical pulse signals generated by a magnetic encoder. The method is based on accurate determination of the measured global mean angular speed and precise values of times when leading edges of individual magnetic teeth pass through the magnetic sensor. Under a steady-state operating condition, a discrete deviation time vs. shaft rotational angle series of uniform interval is obtained and used for accurate determination of the crankshaft speed and acceleration. The proposed method for identifying sub- and super-harmonic oscillations in the instantaneous angular speeds and accelerations is new and efficient. Experiments were carried out on a three-cylinder four-stroke Saito 450R model aircraft engine and a Solo propeller in connection with a 64-teeth Admotec KL2202 magnetic encoder and an HS-4 data acquisition system. Comparisons with an independent data processing scheme indicate that the proposed method yields noise-free instantaneous angular speeds and is superior to the finite difference based methods commonly used in the literature.

CORRELATION AMONG DAMAGES CAUSED BY YELLOW BEETLE, CLIMATOLOGICAL ELEMENTS AND PRODUCTION OF GUAVA ACCESSES GROWN IN ORGANIC SYSTEM

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JULIANA ALTAFIN GALLI

Full Text Available ABSTRACT The objective of this research was evaluate the damage caused by the yellow beetle on 85 guava accessions and correlations of the damage with the climatological elements and the production of fruit in an orchard of guava conducted in organic system. Ten leaves by access were analyzed containing the injury of insect attack. Each leaf had its foliar area measured by leaf area meter and, after obtaining the total area, the leaf was covered with duct tape, and measure again. The averages were compared by Scott-Knott test at 5% probability. The 15 accessions with highest average damage had the data submitted to the correlation with the minimum and maximum temperature, precipitation and relative humidity. The production was obtained by the number of fruits/plant. The damages are negatively correlated with the mean relative humidity of 7:00h (local time in the period of 14 days prior to the assessments, and negatively affect production. The accessions Saito, L4P16, Monte Alto Comum 1 and L5P19 are promising in organic agriculture, for presenting good production and minor damage to insect attack, when compared to others.

Radiation-induced enhancement of antifungal activity of chitosan on fruit-spoiling fungi during postharvest storage

Energy Technology Data Exchange (ETDEWEB)

Diep, Tran Bang; Lam, Nguyen Duy; Quynh, Tran Minh [Institute for Nuclear Science and Technique-VAEC, Hanoi (Viet Nam); Kume, Tamikazu [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment

2001-03-01

Experiment conducted four fruit-spoiling fungal strains that were isolated from spoilt fruits (mango and dragon fruit) and were identified as follows: Fusarium dimerum Penzig, Aspergillus nidulans Wint, Aspergillus fumigatus Fresenius and Aspergillus japonicus Saito. Chitosan samples with various deacetylation degree (70-99%) were irradiated at doses ranging from 20 to 200kGy, then were supplemented to liquid medium for growth of fungi. We have found that chitosan possesses not only well known antibacterial activity but also the antifungal one on fruit-spoiling fungi. Method of fungal cultivation using liquid medium showed that it has higher sensitivity compared with the cultivation on agar plate, so we recommend this method should be used for evaluation of antimicrobial activity of chitosan. Our study also indicated that deacetylation degree of chitosan clearly affects its antifungal activity, the higher the deacetylation of chitosan, stronger antifungal activity can be observed. This finding recommends the use of chitosan with higher deacetylation for fruit coating and other pharmacology utilization. Results from the minimal inhibitory concentrations (MIC) on fungal growth showed that radiation treatment increased antifungal activity of chitosan and dose of 60kGy gave highest activity. (author)

Radiation-induced enhancement of antifungal activity of chitosan on fruit-spoiling fungi during postharvest storage

International Nuclear Information System (INIS)

Diep, Tran Bang; Lam, Nguyen Duy; Quynh, Tran Minh; Kume, Tamikazu

2001-01-01

Experiment conducted four fruit-spoiling fungal strains that were isolated from spoilt fruits (mango and dragon fruit) and were identified as follows: Fusarium dimerum Penzig, Aspergillus nidulans Wint, Aspergillus fumigatus Fresenius and Aspergillus japonicus Saito. Chitosan samples with various deacetylation degree (70-99%) were irradiated at doses ranging from 20 to 200kGy, then were supplemented to liquid medium for growth of fungi. We have found that chitosan possesses not only well known antibacterial activity but also the antifungal one on fruit-spoiling fungi. Method of fungal cultivation using liquid medium showed that it has higher sensitivity compared with the cultivation on agar plate, so we recommend this method should be used for evaluation of antimicrobial activity of chitosan. Our study also indicated that deacetylation degree of chitosan clearly affects its antifungal activity, the higher the deacetylation of chitosan, stronger antifungal activity can be observed. This finding recommends the use of chitosan with higher deacetylation for fruit coating and other pharmacology utilization. Results from the minimal inhibitory concentrations (MIC) on fungal growth showed that radiation treatment increased antifungal activity of chitosan and dose of 60kGy gave highest activity. (author)

PREFACE Preface

Science.gov (United States)

Takahashi, Migaku; Saito, Hitoshi; Yoshimura, Satoru; Takanashi, Koki; Sahashi, Masashi; Tsunoda, Masakiyo

2011-01-01

23 countries, with about 40 percent of participants attending from overseas (see figure). The program involved 4 plenary talks (45 minutes each), 37 invited talks (30 minutes), 85 contributed talks (15 minutes), and 352 posters. Pie chart Organizing Committee of ISAMMA 2010 M TakahashiTohoku Univ., Japan, Chairman K TakanashiTohoku Univ., Japan, Chair of the Program Committee H SaitoAkita Univ., Japan, Chair of the Publication Committee M SahashiTohoku Univ., Japan, Chair of the Treasury Committee M TsunodaTohoku Univ., Japan, General Secretary H AkinagaAIST, Japan H FukunagaNagasaki Univ., Japan K HonoNIMS, Japan S IshioAkita Univ., Japan S IwataNagoya Univ., Japan K NakagawaNihon Univ., Japan S NakagawaTokyo Inst. of Tech., Japan T OnoKyoto Univ., Japan Y SuzukiOsaka Univ., Japan M TanakaEhime Univ., Japan T Tanaka Univ. of Tokyo, Japan Program Committee of ISAMMA 2010 K TakanashiTohoku Univ., Japan, ChairS MizukamiTohoku Univ., Japan M MizuguchiTohoku Univ., Japan, Vice-chairH NaganumaTohoku Univ., Japan M DoiTohoku Univ., JapanS NakagawaTokyo Inst. of Tech., Japan A FujitaTohoku Univ., JapanK NakamuraTohoku Univ., Japan K IshiyamaTohoku Univ., JapanK OnoKEK, Japan T KatoNagoya Univ., JapanT OnoKyoto Univ., Japan T KawagoeOsaka Pref. Univ.of Edu., JapanF SatoTohoku Univ., Japan O KitakamiTohoku Univ., JapanM ShiraiTohoku Univ., Japan Y KitamotoTokyo Inst. of Tech., JapanS SugimotoTohoku Univ., Japan F MatsukuraTohoku Univ., JapanM YamaguchiTohoku Univ., Japan C MitsumataHitachi Metals, Japan Publication Committee of ISAMMA 2010 H SaitoAkita Univ., Japan, ChairS MitaniNIMS, Japan S YoshimuraAkita Univ., Japan, Vice-chairH MuraokaTohoku, Japan Y AndoTohoku Univ., JapanM NakanoNagasaki Univ., Japan J AriakeAIT, JapanR NakataniOsaka Univ., Japan H AsanoNagoya Univ., JapanK O'GradyUniv. of York, UK M FutamotoChuo Univ., JapanA SakumaTohoku Univ., Japan J HayakawaHitachi, ARL, JapanT SatoKeio Univ., Japan T HondaKyushu Inst. of Tech., JapanT SatoShinshu Univ., Japan M

Development of Spaceborne Radar Simulator by NICT and JAXA using JMA Cloud-resolving Model

Science.gov (United States)

Kubota, T.; Eito, H.; Aonashi, K.; Hashimoto, A.; Iguchi, T.; Hanado, H.; Shimizu, S.; Yoshida, N.; Oki, R.

2009-12-01

We are developing synthetic spaceborne radar data toward a simulation of the Dual-frequency Precipitation Radar (DPR) aboard the Global Precipitation Measurement (GPM) core-satellite. Our purposes are a production of test-bed data for higher level DPR algorithm developers, in addition to a diagnosis of a cloud resolving model (CRM). To make the synthetic data, we utilize the CRM by the Japan Meteorological Agency (JMA-NHM) (Ikawa and Saito 1991, Saito et al. 2006, 2007), and the spaceborne radar simulation algorithm by the National Institute of Information and Communications Technology (NICT) and the Japan Aerospace Exploration Agency (JAXA) named as the Integrated Satellite Observation Simulator for Radar (ISOSIM-Radar). The ISOSIM-Radar simulates received power data in a field of view of the spaceborne radar with consideration to a scan angle of the radar (Oouchi et al. 2002, Kubota et al. 2009). The received power data are computed with gaseous and hydrometeor attenuations taken into account. The backscattering and extinction coefficients are calculated assuming the Mie approximation for all species. The dielectric constants for solid particles are computed by the Maxwell-Garnett model (Bohren and Battan 1982). Drop size distributions are treated in accordance with those of the JMA-NHM. We assume a spherical sea surface, a Gaussian antenna pattern, and 49 antenna beam directions for scan angles from -17 to 17 deg. in the PR. In this study, we report the diagnosis of the JMA-NHM with reference to the TRMM Precipitation Radar (PR) and CloudSat Cloud Profiling Radar (CPR) using the ISOSIM-Radar from the view of comparisons in cloud microphysics schemes of the JMA-NHM. We tested three kinds of explicit bulk microphysics schemes based on Lin et al. (1983), that is, three-ice 1-moment scheme, three-ice 2-moment scheme (Eito and Aonashi 2009), and newly developed four-ice full 2-moment scheme (Hashimoto 2008). The hydrometeor species considered here are rain, graupel

Efficacy of everolimus in ABO-incompatible kidney transplantation: a retrospective study

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Tsujimura K

2017-09-01

Full Text Available Kazuma Tsujimura,1 Morihito Ota,1 Kiyoshi Chinen,1 Kiyomitsu Nagayama,2 Masato Oroku,2 Morikuni Nishihira,2 Yoshiki Shiohira,2 Kunitoshi Iseki,3 Hideki Ishida,4 Kazunari Tanabe4 1Department of Surgery, 2Department of Nephrology, 3Clinical Research Support Center, Tomishiro Central Hospital, Okinawa, Japan; 4Department of Urology, Tokyo Women’s Medical University, Tokyo, Japan Background: There are limited reports on the use of everolimus for maintaining immunosuppression in ABO-incompatible (ABOi kidney transplantation (KT. As everolimus (EVR is effective for preventing calcineurin inhibitor (CNI nephrotoxicity without increasing the risk of chronic rejection and viral infection, we aimed to assess the efficacy of EVR in ABOi KT.Patients and methods: We retrospectively studied 22 patients who underwent KT and received EVR. Patients in the ABOi KT group (n=7 were compared with those in the ABO-compatible kidney transplantation group (ABOc KT; n=15. We recorded the frequency of CNI nephrotoxicity, chronic rejection, and viral infection in the 2 groups.Results: CNI nephrotoxicity, chronic rejection, and viral infection occurred in the ABOi KT and ANOc KT groups at rates of 28.3% (2/7 patients and 13.3% (2/15 patients (P=0.388, 28.3% (2/7 patients and 26.7% (4/15 patients (P=0.926, and 14.3% (1/7 patients and 26.7% (4/15 patients (P=0.517, respectively.Conclusion: Administration of EVR is effective in preventing CNI nephrotoxicity after KT. The rate of CNI nephrotoxicity was lower in the ABOc KT group than in the ABOi KT group. The rate of chronic rejection and viral infection was comparable between the groups. This study was conducted in a small cohort of patients. Hence, further evaluation with large sample sizes is necessary in the future to confirm the outcomes. Keywords: blood group incompatibility, immunosuppression, kidney transplantation

A perturbative approach to the redshift space correlation function: beyond the Standard Model

Science.gov (United States)

Bose, Benjamin; Koyama, Kazuya

2017-08-01

We extend our previous redshift space power spectrum code to the redshift space correlation function. Here we focus on the Gaussian Streaming Model (GSM). Again, the code accommodates a wide range of modified gravity and dark energy models. For the non-linear real space correlation function used in the GSM we use the Fourier transform of the RegPT 1-loop matter power spectrum. We compare predictions of the GSM for a Vainshtein screened and Chameleon screened model as well as GR. These predictions are compared to the Fourier transform of the Taruya, Nishimichi and Saito (TNS) redshift space power spectrum model which is fit to N-body data. We find very good agreement between the Fourier transform of the TNS model and the GSM predictions, with <= 6% deviations in the first two correlation function multipoles for all models for redshift space separations in 50Mpch <= s <= 180Mpc/h. Excellent agreement is found in the differences between the modified gravity and GR multipole predictions for both approaches to the redshift space correlation function, highlighting their matched ability in picking up deviations from GR. We elucidate the timeliness of such non-standard templates at the dawn of stage-IV surveys and discuss necessary preparations and extensions needed for upcoming high quality data.

Liposome Disruption Assay to Examine Lytic Properties of Biomolecules.

Science.gov (United States)

Jimah, John R; Schlesinger, Paul H; Tolia, Niraj H

2017-08-05

Proteins may have three dimensional structural or amino acid features that suggest a role in targeting and disrupting lipids within cell membranes. It is often necessary to experimentally investigate if these proteins and biomolecules are able to disrupt membranes in order to conclusively characterize the function of these biomolecules. Here, we describe an in vitro assay to evaluate the membrane lytic properties of proteins and biomolecules. Large unilamellar vesicles (liposomes) containing carboxyfluorescein at fluorescence-quenching concentrations are treated with the biomolecule of interest. A resulting increase in fluorescence due to leakage of the dye from liposomes and subsequent dilution in the buffer demonstrates that the biomolecule is sufficient for disrupting liposomes and membranes. Additionally, since liposome disruption may occur via pore-formation or via general solubilization of lipids similar to detergents, we provide a method to distinguish between these two mechanisms. Pore-formation can be identified and evaluated by examining the blockade of carboxyfluorescein release with dextran molecules that fit the pore. The methods described here were used to determine that the malaria vaccine candidate CelTOS and proapoptotic Bax disrupt liposomes by pore formation (Saito et al. , 2000; Jimah et al. , 2016). Since membrane lipid binding by a biomolecule precedes membrane disruption, we recommend the companion protocol: Jimah et al. , 2017.

Survey of studies on the flow and heat transfer of two-component, two-phase flow of liquid metal in magnetic field

International Nuclear Information System (INIS)

Kumamaru, Hiroshige

1980-01-01

Brief review of the studies on the flow and heat transfer of two-component, two-phase flow of liquid metal in magnetic field is presented. R.J. Thome measured the distribution of void rate, slip ratio and pressure loss for the two-phase flow of NaK-N 2 under vertical magnetic field. The void rate distribution became even and the slip ratio increased with the increasing magnetic field. The experimental results of pressure loss was compared with the calculation by an equation derived from the homogeneous flow model. R.G. Owen et al. made the analytical studies of the MHD friction loss of two phase flow. Michiyoshi et al. made experimental studies on the hydrodynamic local properties of Hg-Ar two-phase flow of slug region in a vertically ascending tube under magnetic field, and Kimi et al. also made studies on the heat transfer of Hg-Ar flow under magnetic field. Saito et al. measured the slip ratio and pressure loss of NaK-N 2 flow. As a whole, it can be said that the average void rate decreases, and its distribution becomes even under magnetic field. The slip ratio increases, and the friction loss factor becomes nearly one. It was hard to make clear the heat transfer characteristics. (Kato, T.)

The in vivo situation of 3H-Aescin which had been administered orally and subcutaneously to rats

International Nuclear Information System (INIS)

Suga, Tetsuya; Matsumoto, Yoshio; Hayase, Shigeru.

1975-01-01

The in vivo situation of the Aescin, a product of aesculus hippocastanum, was examined by administering the 3 H labelled compounds to rats. The following results were obtained: 1) The intestinal absorption from oral administration was not so fast. The blood concentration was low, and its combination with plasma protein was slight. 2) As for the distribution in the organs after an oral administration, the affinity was relatively high in the following organs: Pancreas>heart>kidney>adrenal>gland>lung>muscle>liver. However, the concentrations were extremely low being shown by a ng unit per g tissue in the organs. 3) When it was administered orally to the pregnant rats, the concentrations which were transmitted to the fetuses were low. 4) On the 7th day after oral administration, excretion into the urine was less than 3% and in the feces was more than 70%. The bile excretion was also observed. 5) The metabolic products in the excretion after the oral administration were examined by the method. A large amount of Aescin was excreted in an unchanged form or in compounds. From this, Aescin is presumed to be metabolised by the activity of intestinal bacterial enzymes. 6) The absorption of this drug into the body was low when it was intracutaneously administered. (Saito, K.)

Comparative study in Japan and China concerning aspiration of Asian women towards quality of skin fairness

Science.gov (United States)

Saito, Miho; Matsumoto, Junko; Date, Akira; Li, Junfang

2002-06-01

Beauty is a world common aspiration, but perceptions of what make a woman beautiful vary across culture and countries. A series of Saito's studies indicated that unlike much of the Western world, in Asia, one common desire is fairer skin tone that epitomizes feminine beauty. Using 105 Japanese women and 105 Chinese women as subjects, a comparative study concerning aspiration of Asian Women toward skin fairness was conducted. In this study, four real skin photo images that have skin tone variations (fair/dark) and skin texture variations (rough/smooth) were used. The fifty-two words describe personality were shown to the subject. The subjects were required to match a suitable skin photo image to the descriptive words. The overall result between China and Japan were very consistent. Both in China and Japan, fairer skin tone with smoother skin texture was accepted very positively. Fairer skin tone with rougher texture tends to provide passive and conservative impression while smoother skin texture with darker skin tone tends to provide friendly and delight impression. The results suggested that in addition to skin tone, the skin texture plays an important role for the personal impressions and it works as a trigger to enhance 'ideal skin fairness' for Asian women.

Multiple evanescent white dot syndrome associated with retinal vasculitis

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Takahashi A

2015-09-01

Full Text Available Akihiro Takahashi, Wataru Saito, Yuki Hashimoto, Susumu Ishida Department of Ophthalmology, Hokkaido University Graduate School of Medicine, Sapporo, Japan Purpose: A recent study revealed thickening of the inner retinal layers in acute stage of multiple evanescent white dot syndrome (MEWDS; however, the pathogenesis is still unknown. We report two cases with MEWDS whose funduscopy showed obvious retinal vasculitis. Methods: Case reports. Results: Healthy myopic 16- and 27-year-old women were the cases under study. In both cases, funduscopic examination revealed multiple, faint, small, subretinal white dots at the posterior pole to the midperiphery and macular granularity oculus dexter. Retinal vascular sheathing was also observed at midperiphery. Late-phase fluorescein angiography revealed leakages corresponding to the vascular sheathing. Enhanced depth imaging optical coherence tomography revealed the discontinuity of the ellipsoid zone corresponding to the white dots and increased macular choroidal thickness. One month later, these white dots and retinal sheathing spontaneously resolved in both cases. Three months later, impairments of the outer retinal morphology and the visual acuity were restored. Conclusion: These results suggest that retinal vasculitis possibly plays a role in the pathogenesis of thickened inner retinal layers in acute stage of MEWDS. Keywords: enhanced depth imaging optical coherence tomography, choroidal thickness, inner retinal layer, retinal vascular sheathing

Mucorales isolados do solo de mineração de cobre e produção de amilase e inulinase Mucorales isolated from copper-mining soils and production of amylase and inulinase

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André Luiz Cabral Monteiro Azevedo Santiago

2006-09-01

Full Text Available A presença de metais pesados no solo proporciona impacto sobre os microrganismos, vegetação e os processos funcionais do ecossistema. Visando comprovar que Mucorales são afetados pela extração de cobre na Mineradora Caraíba, Jaguarari, BA, espécies de Mucorales foram isoladas de amostras de solo coletadas nas épocas seca e chuvosa. Os Mucorales foram identificados e caracterizados quanto à capacidade de degradar amido e inulina. Utilizando os métodos de diluição e placa de solo, foram obtidos 46 isolados de Mucorales pertencentes a sete diferentes espécies. Absidia blakesleeana Lendner, A. cylindrospora Hagem, A. hialospora (Saito Lendn., Cunninghamella elegans Lendner, Rhizopus microsporus V. Thieghen, R. oryzae Went. & Prinsen Geerl. e Syncephalastrum racemosum (Cohn. Schroet. foram isolados na época seca. A. blakesleeana e A. hialospora foram isoladas apenas na época chuvosa. Rhizopus oryzae apresentou maior número de isolados (30,43%, seguido por A. blakesleeana (26,09% e C. elegans (21,74%. O gênero que apresentou maior número de espécies foi Absidia seguido por Rhizopus. Entre as áreas, houve diferenças significativas no número de isolados de Mucorales, comprovando os efeitos negativos do impacto ambiental na abundância de Mucorales nos solos impactados. Todas as espécies degradaram o amido e apenas C. elegans degradou também inulina. Culturas de mesma espécie isoladas de áreas diferentes apresentaram o mesmo comportamento quanto à degradação de amido e inulina.The presence of heavy metals in soil causes impact on microorganisms, vegetation and functional processes in ecosystems. Aiming to prove that Mucorales are affected by copper extraction at the Caraíba mining site, Jaguarari, Bahia, species of Mucorales were isolated from samples collected in the dry and wet seasons. Mucorales were identified and characterized according to their capacity to degrade starch and inulin. Forty six isolates from seven

Aggregation is a critical cause of poor transfer into the brain tissue of intravenously administered cationic PAMAM dendrimer nanoparticles

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Kurokawa Y

2017-05-01

Full Text Available Yoshika Kurokawa,1 Hideko Sone,1 Tin-Tin Win-Shwe,1 Yang Zeng,1 Hiroyuki Kimura,2 Yosuke Koyama,1 Yusuke Yagi,2 Yasuto Matsui,3 Masashi Yamazaki,4 Seishiro Hirano1 1Center for Health and Environmental Risk Research, National Institute for Environmental Studies, Tsukuba, Ibaraki, 2Department of Analytical and Bioinorganic Chemistry, Kyoto Pharmaceutical University, 3Department of Environmental Engineering, Kyoto University Graduate School of Engineering, Kyoto, 4TIA Center Office, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan Abstract: Dendrimers have been expected as excellent nanodevices for brain medication. An amine-terminated polyamidoamine dendrimer (PD, an unmodified plain type of PD, has the obvious disadvantage of cytotoxicity, but still serves as an attractive molecule because it easily adheres to the cell surface, facilitating easy cellular uptake. Single-photon emission computed tomographic imaging of a mouse following intravenous injection of a radiolabeled PD failed to reveal any signal in the intracranial region. Furthermore, examination of the permeability of PD particles across the blood–brain barrier (BBB in vitro using a commercially available kit revealed poor permeability of the nanoparticles, which was suppressed by an inhibitor of caveolae-mediated endocytosis, but not by an inhibitor of macropinocytosis. Physicochemical analysis of the PD revealed that cationic PDs are likely to aggregate promptly upon mixing with body fluids and that this prompt aggregation is probably driven by non-Derjaguin–Landau–Verwey–Overbeek attractive forces originating from the surrounding divalent ions. Atomic force microscopy observation of a freshly cleaved mica plate soaked in dendrimer suspension (culture media confirmed prompt aggregation. Our study revealed poor transfer of intravenously administered cationic PDs into the intracranial nervous tissue, and the results of our analysis

Age-dependent change of HMGB1 and DNA double-strand break accumulation in mouse brain

International Nuclear Information System (INIS)

Enokido, Yasushi; Yoshitake, Ayaka; Ito, Hikaru; Okazawa, Hitoshi

2008-01-01

HMGB1 is an evolutionarily conserved non-histone chromatin-associated protein with key roles in maintenance of nuclear homeostasis; however, the function of HMGB1 in the brain remains largely unknown. Recently, we found that the reduction of nuclear HMGB1 protein level in the nucleus associates with DNA double-strand break (DDSB)-mediated neuronal damage in Huntington's disease [M.L. Qi, K. Tagawa, Y. Enokido, N. Yoshimura, Y. Wada, K. Watase, S. Ishiura, I. Kanazawa, J. Botas, M. Saitoe, E.E. Wanker, H. Okazawa, Proteome analysis of soluble nuclear proteins reveals that HMGB1/2 suppress genotoxic stress in polyglutamine diseases, Nat. Cell Biol. 9 (2007) 402-414]. In this study, we analyze the region- and cell type-specific changes of HMGB1 and DDSB accumulation during the aging of mouse brain. HMGB1 is localized in the nuclei of neurons and astrocytes, and the protein level changes in various brain regions age-dependently. HMGB1 reduces in neurons, whereas it increases in astrocytes during aging. In contrast, DDSB remarkably accumulates in neurons, but it does not change significantly in astrocytes during aging. These results indicate that HMGB1 expression during aging is differentially regulated between neurons and astrocytes, and suggest that the reduction of nuclear HMGB1 might be causative for DDSB in neurons of the aged brain

A perturbative approach to the redshift space correlation function: beyond the Standard Model

Energy Technology Data Exchange (ETDEWEB)

Bose, Benjamin; Koyama, Kazuya, E-mail: benjamin.bose@port.ac.uk, E-mail: kazuya.koyama@port.ac.uk [Institute of Cosmology and Gravitation, University of Portsmouth, Burnaby Road, Portsmouth, Hampshire, PO1 3FX (United Kingdom)

2017-08-01

We extend our previous redshift space power spectrum code to the redshift space correlation function. Here we focus on the Gaussian Streaming Model (GSM). Again, the code accommodates a wide range of modified gravity and dark energy models. For the non-linear real space correlation function used in the GSM we use the Fourier transform of the RegPT 1-loop matter power spectrum. We compare predictions of the GSM for a Vainshtein screened and Chameleon screened model as well as GR. These predictions are compared to the Fourier transform of the Taruya, Nishimichi and Saito (TNS) redshift space power spectrum model which is fit to N-body data. We find very good agreement between the Fourier transform of the TNS model and the GSM predictions, with ≤ 6% deviations in the first two correlation function multipoles for all models for redshift space separations in 50Mpc h ≤ s ≤ 180Mpc/ h . Excellent agreement is found in the differences between the modified gravity and GR multipole predictions for both approaches to the redshift space correlation function, highlighting their matched ability in picking up deviations from GR. We elucidate the timeliness of such non-standard templates at the dawn of stage-IV surveys and discuss necessary preparations and extensions needed for upcoming high quality data.

Pyrene degradation by yeasts and filamentous fungi.

Science.gov (United States)

Romero, M Cristina; Salvioli, Mónica L; Cazau, M Cecilia; Arambarri, A M

2002-01-01

The saprotrophic soil fungi Fusarium solani (Mart.) Sacc., Cylindrocarpon didymum (Hartig) Wollenw, Penicillium variabile Sopp. and the yeasts Rhodotorula glutinis (Fresenius) Harrison and Rhodotorula minuta (Saito) Harrison were cultured in mineral medium with pyrene. The remaining pyrene concentrations were periodically determined during 20 incubation days, using HPLC. To assess the metabolism of pyrene degradation we added 0.1 microCi of [4,5,9,10] 14C-pyrene to each fungi culture and measured the radioactivity in the volatile organic substances, extractable, aqueous phase, biomass and 14CO2 fractions. The assays demonstrated that F. solani and R. glutinis metabolized pyrene as a sole source of carbon. Differences in their activities at the beginning of the cultures disappeared by the end of the experiment, when 32 and 37% of the original pyrene concentration was detected, for the soil fungi and yeasts, respectively. Among the filamentous fungi, F. solani was highly active and oxidized pyrene; moreover, small but significant degradation rates were observed in C. didymum and P. variahile cultures. An increase in the 14CO2 evolution was observed at the 17th day with cosubstrate. R. glutinis and R. minuta cultures showed similar ability to biotransform pyrene, and that 35% of the initial concentration was consumed at the end of the assay. The same results were obtained in the experiments with or without glucose as cosubstrate.

Overcoming Japan’s Imperial Legacies: A Review Essay

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Sherzod Muminov

2017-12-01

Full Text Available Yukiko Koga. Inheritance of Loss: China, Japan, and the Political Economy of Redemption after Empire. Chicago, IL: University of Chicago Press, 2016. Hiro Saito. The History Problem: The Politics of War Commemoration in East Asia. Honolulu: University of Hawai‘i Press, 2016. Japan’s war for empire ended in September 1945, as World War II drew to a close. Pinpointing its outbreak, however, is less straightforward: did it start with the July 1937 Marco Polo Bridge Incident, with the September 1931 Manchurian Incident, or, earlier yet, with the 1910 annexation of Korea? The lack of a single accepted narrative is symptomatic of broader divisions over history between Japan and its neighbors, primarily China and South Korea. As a result, the path toward reconciliation has proven tortuous, beset on all sides by persistent disagreements about past events. Two new books approach these disputes from the perspectives of anthropology (Yukiko Koga’s Inheritance of Loss and sociology (Hiro Saito’s The History Problem, highlighting the complexity of imperial vestiges inherited by the current generations in East Asia. From their distinct yet complementary vantage points, both books enrich the debate on the outcomes of the Second World War in East Asia. Their findings illuminate the obstacles on the way to reconciliation, but also highlight the potential for compromise.

Analysis of fuel-coolant interaction with VAPEX code

International Nuclear Information System (INIS)

Melikhov, O.I.; Melikhov, V.I.; Sokolin, A.V.; Yakush, S.E.

2004-01-01

The analysis of the FARO L-33 test has been carried out with the VAPEX code in which a submodel for hydrogen release and transport was implemented. The FARO test was aimed at studying the premixing and quenching processes for large (about 100 kg) masses of corium. The specific features of the FARO L-33 test are: high subcooling (124 K), low pressure (4.1 bar), presence of non-condensable gas (argon) and triggered vapor explosion when melt reached the bottom of the vessel. A numerical simulation of FARO L-33 test was carried out using 2-D nodalization. The fragmentation model is based on the Saito correlation. The model for hydrogen release assumes direct proportionality between the total hydrogen mass release rate and the total fragmentation rate of the melt jet. The proportionality constant was taken from the experimental estimates for test conditions. Calculation of the premixing stage gave some delay in the pressure growth, which is most probably connected with inadequacy of the fragmentation model at the initial stage of melt jet-water interaction. The calculated pressurization rate, however, agrees reasonably with the measured one. Modeling of vapor explosion, which occurred in the test, yielded reasonable correlation with the test data when hydrogen formation was taken into account. Thus, VAPEX analysis of the FARO L-33 test has shown reasonable agreement between the experimental and calculated data. (author)

Media, Mobilities and Identity in East and Southeast Asia: Introduction

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Dan Edwards

2017-05-01

Full Text Available This collection for Cultural Studies Review aims to address gaps in existing mobilities scholarship from two perspectives. First, while several articles here discuss the physical movement of various groups, the overarching focus is the complex interplay of mobile technologies and information on the one hand, and rapidly evolving formations of culture and identity on the other. Geographically, our focus is outside the ‘global north’, on a region that has perhaps been more dramatically transformed by physical, cultural and informational mobility than any other: East and Southeast Asia. Rather than taking ‘Asia’ as a category of cultural identity, this collection conceptualises the geographic region as a zone of cultural and political plurality, in which a vast array of migrations, imaginings, representations and discourses are constantly bumping up against political and cultural borders, as well as various state-sponsored and state-sanctioned ideas and images, in fascinating and often highly volatile ways. Topic covered in this collection include Hong Kong working holidaymakers in Australia (Louis Ho, literary narratives of overseas adoptees who have returned to South Korea (Ethan Waddell, online debates and conflicts between Chinese migrants and local Chinese-Singaporeans (Sylvia Ang, the politics of representing urban demolition and relocation in independent Chinese documentaries (Dan Edwards, the ‘glocalisation’ of Japanese anime culture in the online space in China (Asako Saito and the representation of migrant worker experience in South Korean cinema (Sina Kim.

Moreton wave, "EIT wave", and type II radio burst as manifestations of a single wave front

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Kuzmenko, I. V.; Grechnev, V. V.; Uralov, A. M.

2011-12-01

We show that a Moreton wave, an "EIT wave," and a type II radio burst observed during a solar flare of July 13, 2004, might have been a manifestation of a single front of a decelerating shock wave, which appeared in an active region (AR) during a filament eruption. We propose describing a quasi-spheroidal wave propagating upward and along the solar surface by using relations known from a theory of a point-like explosion in a gas whose density changes along the radius according to a power law. By applying this law to fit the drop in density of the coronal plasma enveloping the solar active region, we first managed to bring the measured positions and velocities of surface Moreton wave and "EIT wave" into correspondence with the observed frequency drift rate of the meter type II radio burst. The exponent of the vertical coronal density falloff is selected by fitting the power law to the Newkirk and Saito empirical distributions in the height range of interest. Formal use of such a dependence in the horizontal direction with a different exponent appears to be reasonable up to distances of less than 200 Mm around the eruption center. It is possible to assume that the near-surface shock wave weakens when leaving this radius and finally the active region, entering the region of the quiet Sun where the coronal plasma density and the fast-mode speed are almost constant along the horizontal.

Evaluation of biocompatibility of the membrane of cellulose acetate in dogs with acute renal failure undergoing hemodialysis

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Andre Marcelo Conceição Meneses

2014-12-01

Full Text Available ABSTRACT. Meneses A.M.C., Saito M.E., Moraes C.C.G., Souza N.F., Bastos R.K.G., Luz M.A., Seixas L.S., Melchert A. & Caramori J.C.T. [Evaluation of biocompatibility of the membrane of cellulose acetate in dogs with acute renal failure undergoing hemodialysis.] Avaliação da biocompatibilidade da membrana de acetato de celulose em cães com insuficiência renal aguda submetidos à hemodiálise. Revista Brasileira de Medicina Veterinária, 36(4:362-366, 2014. Instituto da saúde e Produção Animal na Amazônia, Universidade Federal Rural da Amazônia, Avenida Presidente Tancredo Neves, 2501, Montese, Belém, PA 66077-530, Brasil. E-mail: andre.meneses@ufra.edu.br In order to evaluate the biocompatibility of the membrane of cellulose acetate in dogs with acute renal failure (ARF, undergoing hemodialysis, were used two groups, one consisting of eight normal dogs and the other by eight dogs with ARF induced by gentamicin. Each animal underwent five hemodialysis sessions, with intervals of 24 hours between each one. A significant reduction in urea and creatinine, whereas the other biochemical values were not different between groups, as well as blood pressure, red cell count, white blood cell count and activated clotting time. High levels of TNF-α was found in sick animals, with no detection of this cytokine in normal animals.

Holocene evolution of a wave-dominated fan-delta: Godavari delta, India

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Saito, Y.; Nageswara Rao, K.; Nagakumar, K.; Demudu, G.; Rajawat, A.; Kubo, S.; Li, Z.

2013-12-01

sediments also indicates erosional environments during the formation of the linear shoreline. We interpret this unconformity as a wave-ravinement surface in a regressive delta succession reflecting the decrease of sediment supply due to lobe shifts (or avulsion), and not as a marine erosion surface due to forced regression. Similar erosion surface is recognized in the Yellow River delta (Saito et al., 2000). Discrimination of either surface for ancient sediments and rocks in a wave-dominated setting will be important in sequence-stratigraphic interpretation. Coastal erosion and deposition have occurred in wave-dominated deltas naturally on centennial to millenneial time scales, resulting in delta progradation during the Holocene. However recent decrease of sediment discharge due to dam construction and irrigation on decadal time scales has been exacerbating coastal erosion significantly, resulting in delta shrinking in the Godavari delta. Nageswara Rao, K., Sadakata, N.: In Kay, R. (Ed.), Deltas of the World. American Society of Civil Engineers, New York, 1-15, 1993. Nageswara Rao, K. et al.: In Bhattacharya, J.P., Gioson, L. (Eds.), River Deltas--Concepts, Models and Examples: SEPM Special Publication 83, 435-451, 2005. Nageswara Rao, K. et al.: Geomorphology 175-176, 163¬-175, 2012. Saito, Y. et al.: J Asian Earth Sci. 18, 489-497, 2000.

Superconductors go organic

International Nuclear Information System (INIS)

Singleton, John; Mielke, Charles

2002-01-01

Superconductors made from organic molecules are revealing fascinating new physics and could offer huge technological potential as well. Solid-state physicists are simple people. They believe that basic research is best carried out on chemically simple materials. Traditionally they have focused on inorganic elements, alloys, and other straightforward compounds. This approach has provided some notable successes. For example, any physicist over 35 will remember the huge fuss surrounding the discovery of high-temperature cuprate superconductors in 1986, which led to the infamous 'Woodstock of physics' meeting the following year. Just before the cuprates were discovered, however, an alternative view had begun to emerge. Physical chemists such as Klaus Bechgaard, Peter Day, Gunzi Saito, Viktor Schegolev and Jack Williams were suggesting that the 'simple-materials-are-best' assumption was misplaced. They argued that some of the most exciting studies in solid-state physics can - and should - be attempted on crystalline organic materials. Although chemically complex, such materials are beautifully simple in other ways, and they can, for example, provide much more information about basic phenomena like superconductivity and magnetism than supposedly simple materials. Physicists eventually embraced these materials with enthusiasm, and the number of papers on crystalline organic metals overtook those on the high-temperature cuprate superconductors three years ago. The gap has widened ever since, and the fact that God and a billion years of evolution have produced a processor based on three-dimensional arrays of molecules, rather than silicon or gallium-arsenide chips, is taken as a good omen by those working in the field. (U.K.)

RIKEN SCHOOL ON QCD TOPICS ON THE PROTON

International Nuclear Information System (INIS)

ENYO, H.; HAYAKAWA, M.; KAWAI, H.; SAITO, N.; SHIBATA, T.A.; TADA, T.; WATANABE, Y.; YAZAKI, K.

2003-01-01

The RIKEN School on QCD titled ''Topics on the Proton'' was held on March 26th, 2003 at the Nishina Memorial Hall of RIKEN, Wako, Saitama, Japan, sponsored by REEN (the Institute of Physical and Chemical Research). The school was the third of a new series with a broad perspective of hadron and nuclear physics. The organization and the size of the school were a little different from those of the previous ones. Prof. John Ellis, known as the world best theorist in particle and nuclear physics, has been appointed in RIKEN as an Eminent Scientist, which enables us to plan a collaboration with him for coming three years. As the first year activity, we asked him to give a keynote talk in the JPS spring meeting focusing on the structure of proton, and also to give lectures in RIKEN for younger Japanese scientists on the subjects related the structure of the proton. He kindly agreed on both and we then decided to have a one-day school by supplementing his course with a course on experimental aspects of the proton structure. One of us (N.S.) agreed to give the latter. This time, Theoretical Physics Laboratory joined Radiation Laboratory to organize the school. The purpose of the school was to offer young researchers an opportunity to learn theoretical aspects of the proton structure with a broad perspective including supersymmetry and the related experimental aspects. We had a theoretical course consisting of 3 one-hour lectures by Prof. Ellis and a experimental course consisting of 2 one-hour lectures by Prof. Saito

A patient with acute macular neuroretinopathy and central retinal vein occlusion

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Hirooka K

2013-07-01

Full Text Available Kiriko Hirooka,1 Wataru Saito,1,2 Kousuke Noda,1,2 Susumu Ishida1,21Department of Ophthalmology, Hokkaido University Graduate School of Medicine, Sapporo, Japan; 2Department of Ocular Circulation and Metabolism, Hokkaido University Graduate School of Medicine, Sapporo, JapanPurpose: The precise mechanism causing acute macular neuroretinopathy (AMN is still unknown. A recent report suggested that choroidal circulation impairment correlates with its pathogenesis. We report a rare case with simultaneous onset of AMN and central retinal vein occlusion (CRVO, which is a retinal circulation disorder.Methods: Case report.Results: A 44-year-old woman complained of central visual loss of the left eye for the previous 2 weeks. The patient’s visual acuity was 0.5 in the left eye (OS. Fundoscopic examination revealed a wedge-shaped, dark reddish-brown lesion at the macula, and CRVO-like retinal hemorrhages OS. Fluorescein angiography revealed retinal vasculitis and hypofluorescence corresponding to the macular lesion. The patient’s scanning laser ophthalmoscopy infrared imaging result led to a diagnosis of AMN. Two weeks after corticosteroid pulse therapy, her visual acuity improved to 1.2 OS, with improvement of macular findings and Humphrey perimetry. When the dose of oral corticosteroid was decreased, the AMN lesion worsened, with recurrence of retinal hemorrhages. Visual functions improved again after an increased dose of corticosteroid.Conclusion: These results suggest that circulatory disorders almost simultaneously occurred in choroidal and retinal vessels, resulting in the onset of both AMN and CRVO.Keywords: choroidal circulation, optical coherence tomography, retinal circulation, systemic corticosteroid therapy

Availability of a remote online hemodynamic monitoring system during treatment in a private dental office for medically high-risk patients

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Shinya Yamazaki

2008-09-01

Full Text Available Shinya Yamazaki, Hiroyoshi Kawaai, Shigeo Sasaki, Kazuhiro Shimamura, Hiroshi Segawa, Takahiro SaitoSpecial Care Department in Dentistry, Ohu University Dental Hospital, Koriyama city, Fukushima prefecture, JapanAbstract: The importance of systemic management to prevent accidents is increasing in dentistry because co-morbid illnesses in an aging society and invasive surgical procedures are increasing. In this prefecture, a new medical system called the remote online hemodynamic monitoring system (ROHMs was started in 2001. Eight private dental offices participated in this trial. When dental practitioners feel the risk of a dental procedure, they can contact via ROHMs to this hospital. Then, the hemodynamic data (blood pressure, heart rate, ECG, SpO2, and RPP of the patient in the clinic can be transmitted here via the internet, and the images and the voice can be transmitted as well. The availability of this system was assessed in 66 patients (98 cases. The most frequent complications were hypertension, heart disease, and diabetes mellitus. Systemic management included monitoring during the dental procedure (71.4%, checking vital signs after an interview (15.3%, and monitoring under sedation (13.3%. There were 35.7% of all cases where an unscheduled procedure was necessary for the systemic management. Based on a questionnaire, the majority of the patients felt relieved and safe. This system creates a situation where a specialist is almost present during the procedure. This system will provide significant assistance for future medical cooperation for risk management.Keywords: online, high-risk patient, dental treatment, medical cooperation, medical accident, risk management

Proceedings of the 9th International Symposium on Foundations of Quantum Mechanics in the Light of New Technology

Science.gov (United States)

Ishioka, Sachio; Fujikawa, Kazuo

2009-06-01

Committee -- Obituary: Professor Sadao Nakajima -- Opening address / H. Fukuyama -- Welcoming address / N. Osakabe -- Cold atoms and molecules. Pseudopotential method in cold atom research / C. N. Yang. Symmetry breaking in Bose-Einstein condensates / M. Ueda. Quantized vortices in atomic Bose-Einstein condensates / M. Tsubota. Quantum degenerate gases of Ytterbium atoms / S. Uetake ... [et al.]. Superfluid properties of an ultracold fermi gas in the BCS-BEC crossover region / Y. Ohashi, N. Fukushima. Fermionic superfluidity and the BEC-BCS crossover in ultracold atomic fermi gases / M. W. Zwierlein. Kibble-Zurek mechanism in magnetization of a spinor Bose-Einstein condensate / H. Saito, Y. Kawaguchi, M. Ueda. Quasiparticle inducing Josephson effect in a Bose-Einstein condensate / S. Tsuchiya, Y. Ohashi. Stability of superfluid fermi gases in optical lattices / Y. Yunomae ... [et al.]. Z[symbol] symmetry breaking in multi-band bosonic atoms confined by a two-dimensional harmonic potential / M. Sato, A. Tokuno -- Spin hall effect and anomalous hall effect. Recent advances in anomalous hall effect and spin hall effect / N. Nagaosa. Topological insulators and the quantum spin hall effect / C. L. Kane. Application of direct and inverse spin-hall effects: electric manipulation of spin relaxation and electric detection of spin currents / K. Ando, E. Saitoh. Novel current pumping mechanism by spin dynamics / A. Takeuchi, K. Hosono, G. Tatara. Quantum spin hall phase in bismuth ultrathin film / S. Murakami. Anomalous hall effect due to the vector chirality / K. Taguchi, G. Tatara. Spin current distributions and spin hall effect in nonlocal magnetic nanostructures / R. Sugano ... [et al.]. New boundary critical phenomenon at the metal-quantum spin hall insulator transition / H. Obuse. On scaling behaviors of anomalous hall conductivity in disordered ferromagnets studied with the coherent potential approximation / S. Onoda -- Magnetic domain wall dynamics and spin related

Objective assessment of skin rejuvenation using near-infrared 1064-nm neodymium: YAG laser in Asians

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Tanaka Y

2011-07-01

Full Text Available Yohei Tanaka1,2, Kiyoshi Matsuo1, Shunsuke Yuzuriha11Department of Plastic and Reconstructive Surgery, Shinshu University School of Medicine, Matsumoto, Japan; 2Clinica Tanaka Plastic and Reconstructive Surgery and Anti-aging Center, Matsumoto, JapanBackground: We reported previously that near-infrared (NIR irradiation provides long-lasting stimulation of elastin, and is efficient for skin rejuvenation. Many studies have indicated the efficacy of various types of laser, but did not include sufficiently objective evaluation. Therefore, we evaluated the efficacy of NIR laser treatment not only subjectively but also objectively.Methods: Fifty Japanese patients were treated with a NIR 1064-nm neodymium: YAG laser. Objective computer assessments were performed by Canfield VISIA Complexion Analysis for improvement of dilated pores, skin texture, and wrinkles. The volunteers then provided subjective assessments. Histological evaluations of elastin were performed by Victoria blue staining up to 90 days post-treatment in four Japanese volunteers.Results: Mean pretreatment percentiles of dilated pores, skin texture, and wrinkles were 51.08 ± 24.82, 54.7 ± 26.33, and 58.02 ± 28.61, respectively. Mean post-treatment percentiles of dilated pores, skin texture, and wrinkles were 53.58 ± 23.89, 58.58 ± 24.44, and 62.2 ± 25.39, respectively. All objective computer assessments evaluated by percentiles in dilated pores, skin texture, and wrinkles showed significant improvement after NIR laser treatment. Ninety-six percent, 100%, and 98% of volunteers reported satisfaction with the improvement of dilated pores, skin texture, and wrinkles, respectively. NIR laser treatment appeared to increase the amount of elastin at day 30, which then decreased slightly but was still elevated at day 90 compared with nonirradiated controls on day 0. Thickening of the epidermis was detected on day 30, and epidermal smoothness persisted for up to 90 days. No treatment

Complex comprised of dextran magnetite and conjugated cisplatin exhibiting selective hyperthermic and controlled-release potential

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Akinaga Sonoda

2010-07-01

Full Text Available Akinaga Sonoda1, Norihisa Nitta1, Ayumi Nitta-Seko1, Shinich Ohta1, Shigeyuki Takamatsu2, Yoshio Ikehata3, Isamu Nagano3, Jun-ichiro Jo4, Yasuhiko Tabata4, Masashi Takahashi1, Osamu Matsui3, Kiyoshi Murata11Department of Radiology, Shiga University of Medical Science, Setatsukinowa-cho, Otsu, Shiga, 520-2192, Japan; 2Department of Radiology, Graduate School of Medical Science, Kanazawa University, Takara-machi 13-1, Kanazawa Ishikawa, 920-8641, Japan; 3Department of Natural Science and Technology, Graduate School of Engineering, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192, Japan; 4Department of Biomaterials, Institute for Frontier Medical Sciences, Kyoto University, Shogoin kawara-machi 53, Sakyo-ku 606-8507, Kyoto, JapanAbstract: We developed a dextran-magnetite conjugated cisplatin (DM-Cis complex for use in thermal ablation and as a chemotherapeutic drug. To produce DM-Cis we reacted Cis with 1 mL DM (56 mg/mL iron. The temperature rise of DM-Cis was measured in vitro and in vivo under a portable induction-heating (IH device. Platinum desorption from DM-Cis over 24 hours was measured in bovine serum. In in vivo accumulation and magnet and exothermic experiments we used four rat groups. In group 1 we delivered DM-Cis intraperitoneally (ip and placed magnets subcutaneously (sc. In group 2 we injected saline (ip and placed magnets (sc. In group 3 we injected DM-Cis (ip and placed a sc incision (sham. The control (group 4 received an ip injection of saline. Rectus abdominis muscle tissue was stained with hematoxylin-eosin and iron-stained tissue areas (µm2 were calculated. The maximum platinum concentration in DM-Cis was approximately 105.6 µg/mL. Over 24 hours, 33.48% of platinum from DM-Cis was released. There was a significant difference (P < 0.05 in the iron-stained area between group 1 and the other groups. The temperature in muscle tissue registered a maximum of 56°C after about 4 min. DM-Cis may represent a

Diagnóstico bacteriológico de la tos convulsiva

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Germán Battistini Moore

1944-09-01

Full Text Available El diagnóstico bacteriológico de la tos convulsiva es una necesidad que debe ser efectuada en todo enfermo que presente manifestaciones clínicas incipientes de esta enfermedad. Las técnicas para su realización han sufrido sucesivas modificaciones a fin de obtener ventajas tanto en su simplicidad como en su rendimiento. La técnica de CHIVIETZ y MEYER (1916 ha sido la más usualmente empleada, pero dificultades especialmente de parte del enfermo (espasmo natural, edad, estado físico, etc., diversos investigadores (SUGARE, Mc. LEOD, KRISTENSEN, STRAKER, etc. ensayaron otros métodos realizando siembras directas de secresión laríngea tomada con distintos dispositivos y maniobras, obteniendo más comodidad y mejor rendimiento que el uso de la "placa de tos" (CHIVIETZ y MEYER; posteriormente el método de la torunda de algodón se perfecciona más (BRADFORT, SLAVIN; MORRIS, BRADFORD y PACKER; SAITO, MILLER y LEACH quedando establecido que la mayor efectividad para el diagnóstico bacteriológico de la tos convulsiva es la siembra del exudado naso-faríngeo tomado con una torunda. de algodón. Nosotros hemos ensayado estos distintos métodos encontrando las mismas dificultades, de ahí que guiados por los trabajos de A. FLEMING en el uso de una substancia bacteriostática para aislar mejor el germen, y teniendo la oportunidad de contar precisamente con la adecuada, la penicilina, hemos podido realizar ensayos a este fin, habiendo logrado resultados halagadores, como se puede apreciar en lo expuesto.

Technical note: optimization for improved tube-loading efficiency in the dual-energy computed tomography coupled with balanced filter method.

Science.gov (United States)

Saito, Masatoshi

2010-08-01

This article describes the spectral optimization of dual-energy computed tomography using balanced filters (bf-DECT) to reduce the tube loadings and dose by dedicating to the acquisition of electron density information, which is essential for treatment planning in radiotherapy. For the spectral optimization of bf-DECT, the author calculated the beam-hardening error and air kerma required to achieve a desired noise level in an electron density image of a 50-cm-diameter cylindrical water phantom. The calculation enables the selection of beam parameters such as tube voltage, balanced filter material, and its thickness. The optimal combination of tube voltages was 80 kV/140 kV in conjunction with Tb/Hf and Bi/Mo filter pairs; this combination agrees with that obtained in a previous study [M. Saito, "Spectral optimization for measuring electron density by the dual-energy computed tomography coupled with balanced filter method," Med. Phys. 36, 3631-3642 (2009)], although the thicknesses of the filters that yielded a minimum tube output were slightly different from those obtained in the previous study. The resultant tube loading of a low-energy scan of the present bf-DECT significantly decreased from 57.5 to 4.5 times that of a high-energy scan for conventional DECT. Furthermore, the air kerma of bf-DECT could be reduced to less than that of conventional DECT, while obtaining the same figure of merit for the measurement of electron density and effective atomic number. The tube-loading and dose efficiencies of bf-DECT were considerably improved by sacrificing the quality of the noise level in the images of effective atomic number.

General H-theorem and Entropies that Violate the Second Law

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Alexander N. Gorban

2014-04-01

Full Text Available H-theorem states that the entropy production is nonnegative and, therefore, the entropy of a closed system should monotonically change in time. In information processing, the entropy production is positive for random transformation of signals (the information processing lemma. Originally, the H-theorem and the information processing lemma were proved for the classical Boltzmann-Gibbs-Shannon entropy and for the correspondent divergence (the relative entropy. Many new entropies and divergences have been proposed during last decades and for all of them the H-theorem is needed. This note proposes a simple and general criterion to check whether the H-theorem is valid for a convex divergence H and demonstrates that some of the popular divergences obey no H-theorem. We consider systems with n states Ai that obey first order kinetics (master equation. A convex function H is a Lyapunov function for all master equations with given equilibrium if and only if its conditional minima properly describe the equilibria of pair transitions Ai ⇌ Aj . This theorem does not depend on the principle of detailed balance and is valid for general Markov kinetics. Elementary analysis of pair equilibria demonstrate that the popular Bregman divergences like Euclidian distance or Itakura-Saito distance in the space of distribution cannot be the universal Lyapunov functions for the first-order kinetics and can increase in Markov processes. Therefore, they violate the second law and the information processing lemma. In particular, for these measures of information (divergences random manipulation with data may add information to data. The main results are extended to nonlinear generalized mass action law kinetic equations.

List of participants at SIDE IV meeting, Tokyo, 27 November--1 December 2000

Science.gov (United States)

2001-12-01

Mark J Ablowitz, Vsevolod Adler, Mark Alber, Said Belmehdi, Marco Boiti, Claude Brezinski, R Bullough, Y M Chiang, Theodore Chihara, Peter A Clarkson, Robert Conte, Adam Doliwa, Vladimir Dorodnitsyn, Mitsuaki Eguchi, Claire Gilson, Basil Grammaticos, Valeri Gromak, Rod Halburd, Koji Hasegawa, Jarmo Hietarinta, Ryogo Hirota, Xing Biao Hu, M Idzumi, J Inoguchi, Hiroya Ishikara, Mourad Ismail, Shin Isojima, Kenichi Ito, Yoshiaki Itoh, Masashi Iwasaki, Klara Janglajew, Michio Jimbo, Nalini Joshi, Kenji Kajiwara, Saburo Kakei, Masaru Kamata, Satoshi Kamei, Rinat Kashaev, Shingo Kawai, Taeko Kimijima, K Kimura, Anatol Kirillov, Koichi Kondo, Boris Konopelchenko, Martin Kruskal, Atsuo Kuniba, Wataru Kunishima, Franklin Lambert, Serguei Leble, Decio Levi, Shigeru Maeda, Manuel Manas, Ken-Ichi Maruno, Tetsu Masuda, J Matsukidaira, Atsushi Matsumiya, Shigeki Matsutani, Yukitaka Minesaki, Mikio Murata, Micheline Musette, Atsushi Nagai, Katsuya Nakagawa, Atsushi Nakamula, Akira Nakamura, Yoshimasa Nakamura, Frank Nijhoff, J J C Nimmo, Katsuhiro Nishinari, Michitomo Nishizawa, A Nobe, Masatoshi Noumi, Yaeko Ohsaki, Yasuhiro Ohta, Kazuo Okamoto, Alexandre Orlov, Naoki Osada, Flora Pempinelli, Spiro Pyrlis, Reinout Quispel, Orlando Ragnisco, Alfred Ramani, Jean-Pierre Ramis, Andreas Ruffing, Simon Ruijsenaars, Satoru Saito, Noriko Saitoh, Hidetaka Sakai, Paulo Santini, Narimasa Sasa, Ryu Sasaki, Yoshikatsu Sasaki, Junkichi Satsuma, Sergei Sergeev, Nobuhiko Shinzawa, Evgueni Sklyanin, Juris Suris, Norio Suzuki, Yukiko Tagami, Katsuaki Takahashi, Daisuke Takahashi, Tomoyuki Takenawa, Yoshiro Takeyama, K M Tamizhmani, T Tamizhmani, Kouichi Toda, Morikatsu Toda, Tetsuji Tokihiro, Takayuki Tsuchida, Yohei Tsuchiya, Teruhisa Tsuda, Satoru Tsujimoto, Walter Van Assche, Claude Viallet, Luc Vinet, Shinsuke Watanabe, Yoshihida Watanabe, Ralph Willox, Pavel Winternitz, Yasuhiko Yamada, Yuji Yamada, Jin Yoneda, Haruo Yoshida, Katsuhiko Yoshida, Daisuke Yoshihara, Fumitaka Yura, J

A comparison of measured and calculated values of air kerma rates from 137Cs in soil

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V. P. Ramzaev

2015-01-01

Full Text Available In 2010, a study was conducted to determine the air gamma dose rate from 137Cs deposited in soil. The gamma dose rate measurements and soil sampling were performed at 30 reference plots from the south-west districts of the Bryansk region (Russia that had been heavily contaminated as a result of the Chernobyl accident. The 137Cs inventory in the top 20 cm of soil ranged from 260 kBq m–2 to 2800 kBq m–2. Vertical distributions of 137Cs in soil cores (6 samples per a plot were determined after their sectioning into ten horizontal layers of 2 cm thickness. The vertical distributions of 137Cs in soil were employed to calculate air kerma rates, K, using two independent methods proposed by Saito and Jacob [Radiat. Prot. Dosimetry, 1995, Vol. 58, P. 29–45] and Golikov et al. [Contaminated Forests– Recent Developments in Risk Identification and Future Perspective. Kluwer Academic Publishers, 1999. – P. 333–341]. A very good coincidence between the methods was observed (Spearman’s rank coefficient of correlation = 0.952; P<0.01; on average, a difference between the kerma rates calculated with two methods did not exceed 3%. The calculated air kerma rates agreed with the measured dose rates in air very well (Spearman’s coefficient of correlation = 0.952; P<0.01. For large grassland plots (n=19, the measured dose rates were on average 6% less than the calculated kerma rates. The tested methods for calculating the air dose rate from 137Cs in soil can be recommended for practical studies in radiology and radioecology. 

RIKEN SCHOOL ON QCD TOPICS ON THE PROTON.

Energy Technology Data Exchange (ETDEWEB)

En' yo, H.; Kawai, H.; Saito, N.; Shibata, T. A.; Tada, T.; Watanabe, Y.; Yazaki, K.

2003-10-01

The RIKEN School on QCD titled ''Topics on the Proton'' was held on March 26th, 2003 at the Nishina Memorial Hall of RIKEN, Wako, Saitama, Japan, sponsored by REEN (the Institute of Physical and Chemical Research). The school was the third of a new series with a broad perspective of hadron and nuclear physics. The organization and the size of the school were a little different from those of the previous ones. Prof. John Ellis, known as the world best theorist in particle and nuclear physics, has been appointed in RIKEN as an Eminent Scientist, which enables us to plan a collaboration with him for coming three years. As the first year activity, we asked him to give a keynote talk in the JPS spring meeting focusing on the structure of proton, and also to give lectures in RIKEN for younger Japanese scientists on the subjects related the structure of the proton. He kindly agreed on both and we then decided to have a one-day school by supplementing his course with a course on experimental aspects of the proton structure. One of us (N.S.) agreed to give the latter. This time, Theoretical Physics Laboratory joined Radiation Laboratory to organize the school. The purpose of the school was to offer young researchers an opportunity to learn theoretical aspects of the proton structure with a broad perspective including supersymmetry and the related experimental aspects. We had a theoretical course consisting of 3 one-hour lectures by Prof. Ellis and a experimental course consisting of 2 one-hour lectures by Prof. Saito.

Acceleration training for managing nonalcoholic fatty liver disease: a pilot study

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Oh S

2014-11-01

Full Text Available Sechang Oh,1 Takashi Shida,1 Akemi Sawai,1 Tsuyoshi Maruyama,2 Kiyoshi Eguchi,2 Tomonori Isobe,1 Yoshikazu Okamoto,3 Noriko Someya,4 Kiyoji Tanaka,4 Emi Arai,1 Akiko Tozawa,5 Junichi Shoda1 1Department of Medical Sciences, Faculty of Medicine, University of Tsukuba, 2Department of Rehabilitation, Tsukuba University Hospital, 3Department of Diagnostic Radiology, 4Department of Sports Medicine, Faculty of Health and Sport Sciences, University of Tsukuba, Ibaraki, 5Protea Japan Co Ltd, Chiyoda, Tokyo, Japan Background: While aerobic training is generally recommended as therapeutic exercise in guidelines, the effectiveness of resistance training has recently been reported in the management of nonalcoholic fatty liver disease (NAFLD. Acceleration training (AT is a new training method that provides a physical stimulation effect on skeletal muscles by increasing gravitational acceleration with vibration. AT has recently been indicated as a component of medicine. In this study, we evaluated the effectiveness of AT in the management of NAFLD in obese subjects.Methods: A total of 18 obese patients with NAFLD who had no improvement in liver function test abnormalities and/or steatosis grade after 12 weeks of lifestyle counseling were enrolled in an AT program. These patients attended a 20-minute session of AT twice a week for 12 consecutive weeks.Results: During the AT program, the NAFLD patients showed a modest increase in the strength (+12.6% and cross-sectional area (+3.1% of the quadriceps, coupled with a significant reduction in intramyocellular lipids (−26.4%. Notably, they showed a modest reduction in body weight (−1.9%, abdominal visceral fat area (−3.4%, and hepatic fat content (−8.7%, coupled with a significant reduction in levels of aminotransferase (−15.7%, γ-glutamyltransferase (−14.4%, leptin (−9.7%, interleukin-6 (−26.8%, and tumor necrosis factor-α (−17.9%, and a significant increase of adiponectin (+8.7%. On a health

PREFACE: Preface

Science.gov (United States)

Takahashi, Masahiko; Ueda, Kiyoshi

2011-03-01

the conference. Finally, the chairs would like to express their thanks to all the participants for contributing to lively and fruitful discussions throughout the conference. Masahiko Takahashi and Kiyoshi Ueda International Advisory Board Lorenzo Avaldi (Italy)Klaus Bartschat (USA) Azzedine Lahmam-Bennani (France)Jamal Berakdar (Germany) Nora Berrah (USA)Igor Bray (Australia) XiangJun Chen (China)Claude Dal Cappello (France) Reinhard Dörner (Germany)Alexander Dorn (Germany) Danielle Dowek (France)Alexey Grum-Grzhimailo (Russia) Noriyuki Kouchi (Japan)Birgit Lohmann (Australia) Don Madison (USA)Fernando Martin (Spain) Andrew Murray (England)Bernard Piraux (Belgium) Roberto Rivarola (Argentina)Emma Sokell (Ireland) Giovanni Stefani (Italy) Conference photograph

Development of new promising antimetabolite, DFP-11207 with self-controlled toxicity in rodents

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Fukushima M

2017-06-01

Full Text Available Masakazu Fukushima, Kenzo Iizuka, Cheng Jin, Chun Zhang, Mei Hong, Kiyoshi Eshima Division of Oncology Research and Development, Delta-Fly Pharma Inc., Kawauchi-cho, Tokushima, Japan Abstract: To reduce 5-fluorouracil (5-FU-induced serious toxicities without loss of antitumor activity, we have developed DFP-11207, a novel fluoropyrimidine, which consists of 1-ethoxymethyl-5-fluorouracil (EM-FU; a precursor form of 5-FU, 5-chloro-2,4-dihydroxypyridine (CDHP; an inhibitor of 5-FU degradation, and citrazinic acid (CTA; an inhibitor of 5-FU phosphorylation. In vitro studies of DFP-11207 indicated that it strongly inhibited the degradation of 5-FU by dihydropyrimidine dehydrogenase (DPD in homogenates of the rat liver, and also inhibited the phosphorylation of 5-FU by orotate phosphoribosyltransferase (OPRT in tumor tissues in a similar magnitude of potency by CDHP and CTA, respectively. Especially, DFP-11207 inhibited the intracellular phosphorylation of 5-FU in tumor cells in a dose-dependent manner whereas CTA alone did not protect intracellular 5-FU phosphorylation. These results postulate that DFP-11207 rapidly entered into the cell and the free CTA produced from DFP-11207 inhibited the phosphorylation of 5-FU in the cell. Furthermore, following oral administration of DFP-11207, CTA was found to be highly retained in the gastrointestinal (GI tract compared to other tissues in rats. Interestingly, EM-FU, the prodrug of 5-FU was found to specifically produce 5-FU by various species of liver microsomes. When DFP-11207 was administered to rats, the plasma level of 5-FU was persisted for a long-time with lower Cmax and longer half-life than that from other 5-FU prodrugs. The antitumor activity of DFP-11207 was evaluated in human tumor xenografts in nude rats and found that DFP-11207 showed an antitumor activity in a dose-dependent fashion and its efficacy is equivalent to reference 5-FU drugs. In striking contrast, DFP-11207 manifested no or less 5

Evaluation of atherosclerotic lesions using dextran- and mannan–dextran-coated USPIO: MRI analysis and pathological findings

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Mukaisho K

2012-05-01

Full Text Available Keiko Tsuchiya1, Norihisa Nitta1, Akinaga Sonoda1, Ayumi Nitta-Seko1, Shinichi Ohta1, Masashi Takahashi1, Kiyoshi Murata1, Kenichi Mukaisho2, Masashi Shiomi3, Yasuhiko Tabata4, Satoshi Nohara51Department of Radiology, 2Department of Pathology, Shiga University of Medical Science, Otsu, Shiga, 3Institute for Experimental Animals, Kobe University School of Medicine, Kobe, Hyogo, 4Department of Biomaterials, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, 5Nagoya Research Laboratory, Meito Sangyo, Kiyosu, Aichi, JapanAbstract: Magnetic resonance imaging (MRI can detect atherosclerotic lesions containing accumulations of ultrasmall superparamagnetic iron oxides (USPIO. Positing that improved USPIO with a higher affinity for atherosclerotic plaques would yield better plaque images, we performed MRI and histologic studies to compare the uptake of dextran- and mannan–dextran-coated USPIO (D-USPIO and DM-USPIO, respectively by the atherosclerotic walls of rabbits. We intravenously injected atherosclerotic rabbits with DM-USPIO (n = 5 or D-USPIO (n = 5. Two rabbits were the controls. The doses delivered were 0.08 (dose 1 (n = 1, 0.4 (dose 2 (n = 1, or 0.8 (dose 3 (n = 3 mmol iron/Kg. The dose 3 rabbits underwent in vivo contrast-enhanced magnetic resonance angiography (MRA before and 5 days after USPIO administration. Afterwards, all animals were euthanized, the aortae were removed and subjected to in vitro MRI study. The signal-to-noise ratio (SNR of the aortic wall in the same region of interest (ROI was calculated in both in vivo and in vitro studies. Histological assessment through measurement of iron-positive regions in Prussian blue-stained specimens showed that iron-positive regions were significantly larger in rabbits injected with DM- rather than D-USPIO (P < 0.05 for all doses. In vivo MRA showed that the SNR-reducing effect of DM- was greater than that of D-USPIO (P < 0.05. With in vitro MRI scans, SNR was significantly

Modelling non-linear effects of dark energy

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Bose, Benjamin; Baldi, Marco; Pourtsidou, Alkistis

2018-04-01

We investigate the capabilities of perturbation theory in capturing non-linear effects of dark energy. We test constant and evolving w models, as well as models involving momentum exchange between dark energy and dark matter. Specifically, we compare perturbative predictions at 1-loop level against N-body results for four non-standard equations of state as well as varying degrees of momentum exchange between dark energy and dark matter. The interaction is modelled phenomenologically using a time dependent drag term in the Euler equation. We make comparisons at the level of the matter power spectrum and the redshift space monopole and quadrupole. The multipoles are modelled using the Taruya, Nishimichi and Saito (TNS) redshift space spectrum. We find perturbation theory does very well in capturing non-linear effects coming from dark sector interaction. We isolate and quantify the 1-loop contribution coming from the interaction and from the non-standard equation of state. We find the interaction parameter ξ amplifies scale dependent signatures in the range of scales considered. Non-standard equations of state also give scale dependent signatures within this same regime. In redshift space the match with N-body is improved at smaller scales by the addition of the TNS free parameter σv. To quantify the importance of modelling the interaction, we create mock data sets for varying values of ξ using perturbation theory. This data is given errors typical of Stage IV surveys. We then perform a likelihood analysis using the first two multipoles on these sets and a ξ=0 modelling, ignoring the interaction. We find the fiducial growth parameter f is generally recovered even for very large values of ξ both at z=0.5 and z=1. The ξ=0 modelling is most biased in its estimation of f for the phantom w=‑1.1 case.

The protonation state around TyrD/TyrD• in photosystem II is reflected in its biphasic oxidation kinetics.

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Sjöholm, Johannes; Ho, Felix; Ahmadova, Nigar; Brinkert, Katharina; Hammarström, Leif; Mamedov, Fikret; Styring, Stenbjörn

2017-02-01

The tyrosine residue D2-Tyr160 (Tyr D ) in photosystem II (PSII) can be oxidized through charge equilibrium with the oxygen evolving complex in PSII. The kinetics of the electron transfer from Tyr D has been followed using time-resolved EPR spectroscopy after triggering the oxidation of pre-reduced Tyr D by a short laser flash. After its oxidation Tyr D is observed as a neutral radical (Tyr D • ) indicating that the oxidation is coupled to a deprotonation event. The redox state of Tyr D was reported to be determined by the two water positions identified in the crystal structure of PSII [Saito et al. (2013) Proc. Natl. Acad. Sci. USA 110, 7690]. To assess the mechanism of the proton coupled electron transfer of Tyr D the oxidation kinetics has been followed in the presence of deuterated buffers, thereby resolving the kinetic isotope effect (KIE) of Tyr D oxidation at different H/D concentrations. Two kinetic phases of Tyr D oxidation - the fast phase (msec-sec time range) and the slow phase (tens of seconds time range) were resolved as was previously reported [Vass and Styring (1991) Biochemistry 30, 830]. In the presence of deuterated buffers the kinetics was significantly slower compared to normal buffers. Furthermore, although the kinetics were faster at both high pH and pD values the observed KIE was found to be similar (~2.4) over the whole pL range investigated. We assign the fast and slow oxidation phases to two populations of PSII centers with different water positions, proximal and distal respectively, and discuss possible deprotonation events in the vicinity of Tyr D . Copyright © 2016 Elsevier B.V. All rights reserved.

ERK1/2 activation in human taste bud cells regulates fatty acid signaling and gustatory perception of fat in mice and humans.

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Subramaniam, Selvakumar; Ozdener, Mehmet Hakan; Abdoul-Azize, Souleymane; Saito, Katsuyoshi; Malik, Bilal; Maquart, Guillaume; Hashimoto, Toshihiro; Marambaud, Philippe; Aribi, Mourad; Tordoff, Michael G; Besnard, Philippe; Khan, Naim Akhtar

2016-10-01

Obesity is a major public health problem. An in-depth knowledge of the molecular mechanisms of oro-sensory detection of dietary lipids may help fight it. Humans and rodents can detect fatty acids via lipido-receptors, such as CD36 and GPR120. We studied the implication of the MAPK pathways, in particular, ERK1/2, in the gustatory detection of fatty acids. Linoleic acid, a dietary fatty acid, induced via CD36 the phosphorylation of MEK1/2-ERK1/2-ETS-like transcription factor-1 cascade, which requires Fyn-Src kinase and lipid rafts in human taste bud cells (TBCs). ERK1/2 cascade was activated by Ca 2+ signaling via opening of the calcium-homeostasis modulator-1 (CALHM1) channel. Furthermore, fatty acid-evoked Ca 2+ signaling and ERK1/2 phosphorylation were decreased in both human TBCs after small interfering RNA knockdown of CALHM1 channel and in TBCs from Calhm1 -/- mice. Targeted knockdown of ERK1/2 by small interfering RNA or PD0325901 (MEK1/2 inhibitor) in the tongue and genetic ablation of Erk1 or Calhm1 genes impaired preference for dietary fat in mice. Lingual inhibition of ERK1/2 in healthy volunteers also decreased orogustatory sensitivity for linoleic acid. Our data demonstrate that ERK1/2-MAPK cascade is regulated by the opening of CALHM1 Ca 2+ channel in TBCs to modulate orogustatory detection of dietary lipids in mice and humans.-Subramaniam, S., Ozdener, M. H., Abdoul-Azize, S., Saito, K., Malik, B., Maquart, G., Hashimoto, T., Marambaud, P., Aribi, M., Tordoff, M. G., Besnard, P., Khan, N. A. ERK1/2 activation in human taste bud cells regulates fatty acid signaling and gustatory perception of fat in mice and humans. © FASEB.

Solving Hub Network Problem Using Genetic Algorithm

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Mursyid Hasan Basri

2012-01-01

Full Text Available This paper addresses a network problem that described as follows. There are n ports that interact, and p of those will be designated as hubs. All hubs are fully interconnected. Each spoke will be allocated to only one of available hubs. Direct connection between two spokes is allowed only if they are allocated to the same hub. The latter is a distinct characteristic that differs it from pure hub-and-spoke system. In case of pure hub-and-spoke system, direct connection between two spokes is not allowed. The problem is where to locate hub ports and to which hub a spoke should be allocated so that total transportation cost is minimum. In the first model, there are some additional aspects are taken into consideration in order to achieve a better representation of the problem. The first, weekly service should be accomplished. Secondly, various vessel types should be considered. The last, a concept of inter-hub discount factor is introduced. Regarding the last aspect, it represents cost reduction factor at hub ports due to economies of scale. In practice, it is common that the cost rate for inter-hub movement is less than the cost rate for movement between hub and origin/destination. In this first model, inter-hub discount factor is assumed independent with amount of flows on inter-hub links (denoted as flow-independent discount policy. The results indicated that the patterns of enlargement of container ship size, to some degree, are similar with those in Kurokawa study. However, with regard to hub locations, the results have not represented the real practice. In the proposed model, unsatisfactory result on hub locations is addressed. One aspect that could possibly be improved to find better hub locations is inter-hub discount factor. Then inter-hub discount factor is assumed to depend on amount of inter-hub flows (denoted as flow-dependent discount policy. There are two discount functions examined in this paper. Both functions are characterized by

Towards development of novel immunization strategies against leishmaniasis using PLGA nanoparticles loaded with kinetoplastid membrane protein-11

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Santos DM

2012-04-01

Full Text Available Diego M Santos1, Marcia W Carneiro1, Tatiana R de Moura1, Kiyoshi Fukutani1, Jorge Clarencio1, Manuel Soto2, Socorro Espuelas3,4, Claudia Brodskyn1,5, Aldina Barral1,5, Manoel Barral-Netto1,5, Camila I de Oliveira1,51Centro de Pesquisas Gonçalo Moniz, FIOCRUZ, Salvador, BA, Brazil; 2Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas, Departamento de Biologia Molecular, Universidad Autonoma de Madrid, Madrid; 3Departamento de Farmacia y Tecnología Farmacéutica, 4Instituto de Salud Tropical, Facultad de Farmacia, Universidad de Navarra, Pamplona, Spain; 5Instituto de Investigação em Imunologia, Salvador, BA, BrazilBackground: Vaccine development has been a priority in the fight against leishmaniases, which are vector-borne diseases caused by Leishmania protozoa. Among the different immunization strategies employed to date is inoculation of plasmid DNA coding for parasite antigens, which has a demonstrated ability to induce humoral and cellular immune responses. In this sense, inoculation of plasmid DNA encoding Leishmania kinetoplasmid membrane protein-11 (KMP-11 was able to confer protection against visceral leishmaniasis. However, recently the use of antigen delivery systems such as poly(lactic-co-glycolic acid (PLGA nanoparticles has also proven effective for eliciting protective immune responses.Methods: In the present work, we tested two immunization strategies with the goal of obtaining protection, in terms of lesion development and parasite load, against cutaneous leishmaniasis caused by L. braziliensis. One strategy involved immunization with plasmid DNA encoding L. infantum chagasi KMP-11. Alternatively, mice were primed with PLGA nanoparticles loaded with the recombinant plasmid DNA and boosted using PLGA nanoparticles loaded with recombinant KMP-11.Results: Both immunization strategies elicited detectable cellular immune responses with the presence of both proinflammatory and anti

The effect of exercise frequency on neuropathic pain and pain-related cellular reactions in the spinal cord and midbrain in a rat sciatic nerve injury model

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Sumizono M

2018-02-01

Full Text Available Megumi Sumizono,1,2 Harutoshi Sakakima,1 Shotaro Otsuka,1 Takuto Terashi,1 Kazuki Nakanishi,1,2 Koki Ueda,1,2 Seiya Takada,1,2 Kiyoshi Kikuchi3 1Course of Physical Therapy, School of Health Sciences, Faculty of Medicine, Kagoshima University, Kagoshima, Japan; 2Kirishima Orthopedics, Kirishima, Japan; 3Division of Brain Science, Department of Physiology, Kurume University School of Medicine, Kurume, Japan Background: Exercise regimens are established methods that can relieve neuropathic pain. However, the relationship between frequency and intensity of exercise and multiple cellular responses of exercise-induced alleviation of neuropathic pain is still unclear. We examined the influence of exercise frequency on neuropathic pain and the intracellular responses in a sciatic nerve chronic constriction injury (CCI model. Materials and methods: Rats were assigned to four groups as follows: CCI and high-frequency exercise (HFE group, CCI and low-frequency exercise (LFE group, CCI and no exercise (No-Ex group, and naive animals (control group. Rats ran on a treadmill, at a speed of 20 m/min, for 30 min, for 5 (HFE or 3 (LFE days a week, for a total of 5 weeks. The 50% withdrawal threshold was evaluated for mechanical sensitivity. The activation of glial cells (microglia and astrocytes, expression of brain-derived neurotrophic factor (BDNF and μ-opioid receptor in the spinal dorsal horn and endogenous opioid in the midbrain were examined using immunohistochemistry. Opioid receptor antagonists (naloxone were administered using intraperitoneal injection. Results: The development of neuropathic pain was related to the activation of glial cells, increased BDNF expression, and downregulation of the μ-opioid receptor in the ipsilateral spinal dorsal horn. In the No-Ex group, neuropathic pain showed the highest level of mechanical hypersensitivity at 2 weeks, which improved slightly until 5 weeks after CCI. In both exercise groups, the alleviation of

Biochemical study of human periodontal ligament: preparation of cell attachment materials induced by pulsed electromagnetic fields.

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Kim, K T

1990-09-01

The periodontium, especially the periodontal ligament and alveolar bone, are tissues constantly subjected to physical stress such as occlusion and mastication. This study was designed to explore the effect of the pulsed electromagnetic fields (PEMF) on the cell attachment and the spread of human periodontal ligament fibroblasts (HPLF) and rat osteoblasts (ROB). PEMF are categorized as one type of mechanical stress. HPLF were obtained by the explantation method described by Saito et al. They were then subcultured in Dulbecco's modified Eagle's medium (D-MEM) and supplemented with 2 mg/ml dialyzed fetal calf serum protein (FCSP), 50 micrograms/ml ascorbic acid and penicillin/streptomycin after trypsinization. ROB were isolated from a two-day-old rat calvaria by the sequential bacterial collagenase digestion method described by Dziak and Brand and were subcultured in D-MEM supplemented with FCSP, ascorbic acid and penicillin/streptomycin. After the confluent HPLF were cultured with serum-free MCDB 107 medium, the quiescent HPLF were exposed with or without PEMF for 24 hr. This was followed by the collection of the control conditioned medium (C-CM) and PEMF exposed conditioned medium (PEMF-CM). The cell attachment assay was performed so that the hydrophobic 24 multiwells were coated with the whole conditioned medium or fractionated conditioned medium by a PO-60K column. After coating, heat inactivated BSA blocked nonspecific sites for cell adhesion, and 3H-TdR labeled HPLF or ROB were cultured on the precoated wells. The activity of cell attachment and spreading was determined by the radioactivity of 3H-TdR using a scintillation counter. The characters of cell attachment factors derived from HPLF were hydrophobic, heat labile and proteolytic enzyme digestible. In addition, the fractionated PEMF-CM enhanced the spreading activity of ROB. PEMF induced the 10 KDa which can enhance the HPLF and ROB spreading. Therefore, the cell attachment and spreading factors secreted by

Anatomical etiology of “pseudo-sciatica” from superior cluneal nerve entrapment: a laboratory investigation

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Konno T

2017-11-01

Full Text Available Tomoyuki Konno,1 Yoichi Aota,2 Hiroshi Kuniya,1 Tomoyuki Saito,1 Ning Qu,3 Shogo Hayashi,3 Shinichi Kawata,3 Masahiro Itoh3 1Department of Orthopaedic Surgery, Yokohama City University Graduate School of Medicine, 2Department of Spine & Spinal Cord Surgery, Yokohama Brain and Spine Center, Yokohama, 3Department of Anatomy, Tokyo Medical University, Tokyo, Japan Objective: The superior cluneal nerve (SCN may become entrapped where it pierces the thoracolumbar fascia over the iliac crest; this can cause low back pain (LBP and referred pain radiating into the posterior thigh, calf, and occasionally the foot, producing the condition known as “pseudo-sciatica.” Because the SCN was thought to be a cutaneous branch of the lumbar dorsal rami, originating from the dorsal roots of L1–L3, previous anatomical studies failed to explain why SCN causes “pseudo-sciatica”. The purpose of the present anatomical study was to better elucidate the anatomy and improve the understanding of “pseudo-sciatica” from SCN entrapment. Materials and methods: SCN branches were dissected from their origin to termination in subcutaneous tissue in 16 cadavers (5 male and 11 female with a mean death age of 88 years (range 81–101 years. Special attention was paid to identify SCNs from their emergence from nerve roots and passage through the fascial attachment to the iliac crest. Results: Eighty-one SCN branches were identified originating from T12 to L5 nerve roots with 13 branches passing through the osteofibrous tunnel. These 13 branches originated from L3 (two sides, L4 (six sides, and L5 (five sides. Ten of the 13 branches showed macroscopic entrapment in the tunnel. Conclusion: The majority of SCNs at risk of nerve entrapment originated from the lower lumbar nerve. These anatomical results may explain why patients with SCN entrapment often evince leg pain or tingling that mimics sciatica. Keywords: superior cluneal nerve, entrapment neuropathy, dorsal rami

Lipoprotein glomerulopathy treated with LDL-apheresis (Heparin-induced Extracorporeal Lipoprotein Precipitation system: a case report

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Rivasi Paolo

2009-12-01

Full Text Available Abstract Introduction Lipoprotein glomerulopathy is a glomerulonephritis which was described for the first time by Saito in 1989 and is currently acknowledged as a separate nosological entity. It is histologically characterized by a marked dilatation of the glomerular capillaries and the presence of lipoprotein thrombi in the glomerular lumens. The dyslipidemic profile is similar to that of type III dyslipoproteinemia with Apolipoprotein E values that are often high; proteinuria and renal dysfunction are present. Proteinuria often does not respond to steroid and cytostatic treatments. The phenotypic expression of lipoprotein glomerulopathy is most probably correlated to a genetic alteration of the lipoprotein metabolism (mutation of the Apolipoprotein E coding gene. In literature, lipoprotein glomerulopathies have mainly been reported in Japanese and Chinese subjects, except for three cases in the Caucasian race, reported in France and the USA. Case presentation We describe the case of a 60-year-old female, Caucasian patient suffering from lipoprotein glomerulopathy, carrier of a new mutation on the Apolipoprotein E gene (Apolipoprotein EMODENA, and treated successfully with low density lipoprotein-apheresis with the Heparin induced extracorporeal lipoprotein precipitation system. After a first phase of therapeutic protocol with statins, the patient was admitted for nephrotic syndrome, renal failure and hypertension. Since conventional treatment alone was not able to control dyslipidemia, aphaeretic treatment with heparin-induced Extracorporeal Lipoprotein Precipitation - apheresis (HELP-apheresis was started to maintain angiotensin converting enzyme inhibitor therapy for the treatment of hypertension. Treatment with HELP-apheresis led to a complete remission of the proteinuria in a very short time (four months, as well as control of hypercholesterolemia and renal function recovery. Conclusion According to this case of lipoprotein glomerulopathy

Drug diffusion and biological responses of arteries using a drug-eluting stent with nonuniform coating

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Saito N

2016-03-01

Full Text Available Noboru Saito, Yuhei Mori, Sayaka Uchiyama Terumo Corporation R&D Center, Inokuchi, Nakai-machi, Ashigarakami-gun, Kanagawa, Japan Abstract: The purpose of this study was to determine the effect of a nonuniform coating, abluminal-gradient coating (AGC, which leaves the abluminal surface of the curves and links parts of the stent free from the drug coating, on the diffusion direction of the drug and the biological responses of the artery to drug-eluting stent (DES by comparing the AGC-sirolimus stent and the conventional full-surface coating (CFC sirolimus stent. The study aimed to verify whether the AGC approach was appropriate for the development of a safer DES, minimizing the risks of stent thrombosis due to delayed endothelialization by the drug and distal embolization due to cracking of the coating layer on the hinge parts of the DES on stent expansion. In the in vitro local drug diffusion study, we used rhodamine B as a model drug, and rhodamine B released from the AGC stent diffused predominantly into the abluminal side of the alginate artery model. Conversely, rhodamine B released from the CFC stent quickly spread to the luminal side of the artery model, where endothelial cell regeneration is required. In the biological responses study, the luminal surface of the iliac artery implanted with the AGC-sirolimus stent in a rabbit iliac artery for 2 weeks was completely covered with endothelial-like cells. On the other hand, the luminal surface of the iliac artery implanted with the CFC-sirolimus stent for 2 weeks only showed partial coverage with endothelial-like cells. While thrombosis was observed in two of the three CFC-sirolimus stents, it was observed in only one of the three AGC-sirolimus stents. Taken together, these findings indicate that the designed nonuniform coating (AGC is an appropriate approach to ensure a safer DES. However, the number of studies is limited and a larger study should be conducted to reach a statistically

Importance of New Use of Concrete in Iraq Analysis of Development And Use of Concrete in Architecture

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Mohammed Ridha Shakir Majeed

2015-04-01

on the same era The concert as a structural element dominated the Metabolism architecture that represented by the Japanese architects like Kiyonori Kikutake, Kisho Kurokawa, Noboru Kawazoe, Masato Otakaand and Fumihiko Maki. They visualized the city of the future to be viable, evaluable, expandable, flexible structures that evoked the processes of organic growth as it is in nature. Their developments are often called technocratic and described as avant-garde with a rhetorical character. The Metabolist mega structures heavily relied on advanced technology and adaptable plug-in building techniques in using this material. The research concluded the influences of the concrete as a building material upon the modern and building forms from the outsets. By exploring the history of the material, expanding its characteristics and specifications and later demonstrating the modern architecture movements and architects, this research has achieved its targets to acknowledge the importance of concrete in the current construction market and architectural developments.

Changes in blood biochemical markers before, during, and after a 2-day ultramarathon

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Arakawa K

2016-04-01

Full Text Available Kazuyuki Arakawa,1,2 Akihiro Hosono,2 Kiyoshi Shibata,3 Reza Ghadimi,4 Mizuho Fuku,5 Chiho Goto,6 Nahomi Imaeda,7 Yuko Tokudome,8 Hideki Hoshino,9 Mitsuhiro Marumoto,1,2 Masaaki Kobayashi,10 Sadao Suzuki,2 Shinkan Tokudome1,2,11 1Department of Health and Nutrition Policy, 2Department of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan; 3Department of Public Health and Nutrition, Aichi Gakusen University, Okazaki, Japan; 4Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran; 5Department of Rehabilitation Medicine, Yokohama Stroke and Brain Center, Yokohama, Japan; 6Department of Health and Nutrition, Nagoya Bunri University, Inazawa, Japan; 7Department of Food Science and Nutrition, Nagoya Women’s University, Nagoya, Japan; 8Department of Nutritional Sciences, Nagoya University of Arts and Sciences, Nisshin, Japan; 9Department of Early Childhood Studies, Aichi Bunkyo Women’s College, Inazawa, Japan; 10Department of Orthopaedic Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan; 11National Institute of Health and Nutrition, Tokyo, Japan Abstract: We studied changes in blood markers of 18 nonprofessional, middle-aged runners of a 2-day, 130 km ultramarathon. Blood was sampled at baseline, after the goals on the first and second day, and at three time points (1, 3, and 5/6 days after the race. Blood indices showed three patterns. First pattern indices showed essentially no changes after the two goals and after the race, including red blood cell indices, gamma-glutamyl transferase, and tumor necrosis factor-α. Second pattern markers, including the majority of indices, were elevated during the race (and also after the race for some parameters and then returned to baseline afterward, including hemolysis/red blood cell destruction markers (indirect bilirubin and an iron reservoir index (ferritin, muscle

Case of femoral diaphyseal stress fracture after long-term risedronate administration diagnosed by iliac bone biopsy

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Nagai T

2013-04-01

Full Text Available Takashi Nagai, Keizo Sakamoto, Koji Ishikawa, Emi Saito, Takuma Kuroda, Katsunori Inagaki Department of Orthopaedic Surgery, Showa University School of Medicine, Shinagwa-ku, Tokyo, Japan Abstract: Bisphosphonate excessively inhibits bone resorption and results in pathological fracture of the femur or ilium. The subject of this study was administered risedronate for 7 years; we suspected an easy fracture of the femoral diaphysis. In this study, we report the results of this patient's bone biopsy and bone morphometric analysis. A 76-year-old female patient presented with right femoral pain. Bone mineral density of the anteroposterior surface of the 2nd to 4th lumbar vertebrae (L2-L4 was decreased and levels of bone turnover markers were high. Therefore, we initiated treatment with risedronate. As she continued the medication, urinary levels of cross-linked N-terminal telopeptides of type I collagen and alkaline phosphatase (bone-type isozyme were found to be within the normal ranges. After 7 years of administration, the patient experienced pain when she put weight on the right femur and right femoral pain while walking. Plain radiographic examination revealed polypoid stress fracture-like lesions on the right femoral diaphysis and on the slightly distal-lateral cortical bone. Similar lesions were observed on magnetic resonance imaging and bone scintigraphy. We suspected severely suppressed bone turnover. Bone biopsy was obtained after labeling with tetracycline, and bone morphometric analysis was performed. On microscopic examination, slight double tetracycline labeling was observed. The trabeculae were narrow, and the numbers of osteoblasts and osteoclasts were decreased. Further, rates of bone calcification and bone formation were slow. Hence, we diagnosed fracture as a result of low turnover osteopathy. Risedronate was withdrawn, and Vitamin D3 was administered to improve the bone turnover. At 6 months, abnormal signals on magnetic resonance

Determination of the influence of fluid therapy on hematological and urinary parameters in dogs

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Mariah Gois Ceregatti

2016-09-01

Full Text Available ABSTRACT. Ceregatti M.G., Volpato J., Mattoso C.R.S., da Costa A., Weinert N.C., Tocheto R., Comasseto F. & Saito M.E. [Determination of the influence of fluid therapy on hematological and urinary parameters in dogs.] Determinação da influência da fluidoterapia nos parâmetros hematológicos e urinários em cães. Revista Brasileira de Medicina Veterinária, 38(3:292-298, 2016. Departamento de Medicina Veterinária, Universidade do Estado de Santa Catarina, Avenida Luiz de Camões, 2090, Conta Dinheiro, Lages, SC 88520-000, Brasil. E-mail: jully_volps@hotmail.com The aim of the present study was to evaluate the effects of different fluid infusion rates on hematologic and urinary parameters in dogs. A total of 30 mixed-breed, male dogs were distributed into three groups. Fluid (0.9% NaCl was administered during a one-hour period at rates: G5 (5 mL/ kg; G10 (10 mL/ kg; G50 (50 mL/kg. Blood samples for erythrogram, and urine to perform urine specific gravity were taken over the following time points studied. Urinary volume produced was also evaluated during the same time points. Erythrogram values were statistically lower between T10 and T240 in G10 and G50, compared to T0, and the lowest values were found in G50. Urine specific gravity decreased statistically between all time points only in G50. Statistical differences were found in urinary output between groups, with higher volumes in G50 in most of the time points studied, it can be concluded that fluid therapy changes hematologic indices in rates of 10 and 50 mL/ kg for one hour. At least a four hour period must be respected after the end of infusion to collect blood for erythrogram samples. Fluid therapy affects the urine specific gravity only at high infusion rates (50 mL/kg for 1 hour, and in this case urine samples should be collected after more than 4 hours after the end of infusion, although lower rates (5 and 10 mL / kg for 1 hour do not interfere with urine specific gravity.

Anatomical study of middle cluneal nerve entrapment

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Konno T

2017-06-01

Full Text Available Tomoyuki Konno,1 Yoichi Aota,2 Tomoyuki Saito,1 Ning Qu,3 Shogo Hayashi,3 Shinichi Kawata,3 Masahiro Itoh3 1Department of Orthopaedic Surgery, Yokohama City University, 2Department of Spine and Spinal Cord, Yokohama Brain and Spine Center, Yokohama City, 3Department of Anatomy, Tokyo Medical University, Tokyo, Japan Object: Entrapment of the middle cluneal nerve (MCN under the long posterior sacroiliac ligament (LPSL is a possible, and underdiagnosed, cause of low-back and/or leg symptoms. To date, detailed anatomical studies of MCN entrapment are few. The purpose of this study was to ascertain, using cadavers, the relationship between the MCN and LPSL and to investigate MCN entrapment. Methods: A total of 30 hemipelves from 20 cadaveric donors (15 female, 5 male designated for education or research, were studied by gross anatomical dissection. The age range of the donors at death was 71–101 years with a mean of 88 years. Branches of the MCN were identified under or over the gluteus maximus fascia caudal to the posterior superior iliac spine (PSIS and traced laterally as far as their finest ramification. Special attention was paid to the relationship between the MCN and LPSL. The distance from the branch of the MCN to the PSIS and to the midline and the diameter of the MCN were measured. Results: A total of 64 MCN branches were identified in the 30 hemipelves. Of 64 branches, 10 (16% penetrated the LPSL. The average cephalocaudal distance from the PSIS to where the MCN penetrated the LPSL was 28.5±11.2 mm (9.1–53.7 mm. The distance from the midline was 36.0±6.4 mm (23.5–45.2 mm. The diameter of the MCN branch traversing the LPSL averaged 1.6±0.5 mm (0.5–3.1 mm. Four of the 10 branches penetrating the LPSL had obvious constriction under the ligament. Conclusion: This is the first anatomical study illustrating MCN entrapment. It is likely that MCN entrapment is not a rare clinical entity. Keywords: middle cluneal nerve, sacroiliac joint

How the Blind “See” Braille and the Deaf “Hear” Sign: Lessons from fMRI on the Cross-Modal Plasticity, Integration, and Learning

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Norihiro Sadato

2011-10-01

Full Text Available What does the visual cortex of the blind do during Braille reading? This process involves converting simple tactile information into meaningful patterns that have lexical and semantic properties. The perceptual processing of Braille might be mediated by the somatosensory system, whereas visual letter identity is accomplished within the visual system in sighted people. Recent advances in functional neuroimaging techniques have enabled exploration of the neural substrates of Braille reading (Sadato et al. 1996, 1998, 2002, Cohen et al. 1997, 1999. The primary visual cortex of early-onset blind subjects is functionally relevant to Braille reading, suggesting that the brain shows remarkable plasticity that potentially permits the additional processing of tactile information in the visual cortical areas. Similar cross-modal plasticity is observed by the auditory deprivation: Sign language activates the auditory cortex of deaf subjects (Neville et al. 1999, Nishimura et al. 1999, Sadato et al. 2004. Cross-modal activation can be seen in the sighted and hearing subjects. For example, the tactile shape discrimination of two dimensional (2D shapes (Mah-Jong tiles activated the visual cortex by expert players (Saito et al. 2006, and the lip-reading (visual phonetics (Sadato et al. 2004 or key touch reading by pianists (Hasegawa et al. 2004 activates the auditory cortex of hearing subjects. Thus the cross-modal plasticity by sensory deprivation and cross-modal integration through the learning may share their neural substrates. To clarify the distribution of the neural substrates and their dynamics during cross-modal association learning within several hours, we conducted audio-visual paired association learning of delayed-matching-to-sample type tasks (Tanabe et al. 2005. Each trial consisted of the successive presentation of a pair of stimuli. Subjects had to find pre-defined audio-visual or visuo-visual pairs in a trial and error manner with feedback in

Proceedings of RIKEN BNL Research Center workwhop on RHIC spin

Energy Technology Data Exchange (ETDEWEB)

SOFFER,J.

1999-10-06

This RHIC Spin Workshop is the 1999 annual meeting of the RHIC Spin Collaboration, and the second to be hosted at Brookhaven and sponsored by the RIKEN BNL Research Center. The previous meetings were at Brookhaven (1998), Marseille (1996), MIT in 1995, Argonne 1994, Tucson in 1991, and the Polarized Collider Workshop at Penn State in 1990. As noted last year, the Center provides a home for combined work on spin by theorists, experimenters, and accelerator physicists. This proceedings, as last year, is a compilation of 1 page summaries and 5 selected transparencies for each speaker. It is designed to be available soon after the workshop is completed. Speakers are welcome to include web or other references for additional material. The RHIC spin program and RHIC are rapidly becoming reality. RHIC has completed its first commissioning run, as described here by Steve Peggs. The first Siberian Snake for spin has been completed and is being installed in RHIC. A new polarized source from KEK and Triumf with over 1 milliampere of polarized H{sup minus} is being installed, described by Anatoli Zelenski. They have had a successful test of a new polarimeter for RHIC, described by Kazu Kurita and Haixin Huang. Spin commissioning is expected next spring (2000), and the first physics run for spin is anticipated for spring 2001. The purpose of the workshop is to get everyone together about once per year and discuss goals of the spin program, progress, problems, and new ideas. They also have many separate regular forums on spin. There are spin discussion sessions every Tuesday, now organized by Naohito Saito and Werner Vogelsang. The spin discussion schedule and copies of presentations are posted on http://riksg01.rhic.bnl.gov/rsc. Speakers and other spinners are encouraged to come to BNL and to lead a discussion on your favorite idea. They also have regular polarimeter and snake meetings on alternate Thursdays, led by Bill McGahern, the lead engineer for the accelerator spin

Aloe sterol supplementation improves skin elasticity in Japanese men with sunlight-exposed skin: a 12-week double-blind, randomized controlled trial

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Tanaka M

2016-11-01

Full Text Available Miyuki Tanaka,1 Yuki Yamamoto,2 Eriko Misawa,1 Kazumi Nabeshima,1 Marie Saito,1 Koji Yamauchi,1 Fumiaki Abe,1 Fukumi Furukawa2 1Functional Food Ingredients Department, Food Ingredients & Technology Institute, Morinaga Milk Industry Co., Ltd., Zama, Kanagawa, 2Department of Dermatology, Wakayama Medical University, Kimiidera, Wakayama, Japan Background/objective: Recently, it was confirmed that the daily oral intake of plant sterols of Aloe vera gel (Aloe sterol significantly increases the skin barrier function, moisture, and elasticity in photoprotected skin. This study aimed to investigate whether Aloe sterol intake affected skin conditions following sunlight exposure in Japanese men. Methods: We performed a 12-week, randomized, double-blind, placebo-controlled study to evaluate the effects of oral Aloe sterol supplementation on skin conditions in 48 apparently healthy men (age range: 30–59 years; average: 45 years. The subjects were instructed to expose the measurement position of the arms to the sunlight outdoors every day for 12 weeks. The skin parameters were measured at 0 (baseline, 4, 8, and 12 weeks. Results: Depending on the time for the revelation of the sunlight, the b* value and melanin index increased and the skin moisture decreased. After taking an Aloe sterol tablet daily for 12 weeks, the skin elasticity index (R2, R5, and R7 levels were significantly higher than the baseline value. There were no differences between the groups in these skin elasticity values. In the subgroup analysis of subjects aged <46 years, the change in the R5 and R7 was significantly higher in the Aloe group than in the placebo group at 8 weeks (P=0.0412 and P=0.0410, respectively. There was a difference in the quantity of sun exposure between each subject, and an additional clinical study that standardizes the amount of ultraviolet rays is warranted. No Aloe sterol intake-dependent harmful phenomenon was observed during the intake period

Proceedings of RIKEN BNL Research Center workshop on RHIC spin

International Nuclear Information System (INIS)

Soffer, J.

1999-01-01

This RHIC Spin Workshop is the 1999 annual meeting of the RHIC Spin Collaboration, and the second to be hosted at Brookhaven and sponsored by the RIKEN BNL Research Center. The previous meetings were at Brookhaven (1998), Marseille (1996), MIT in 1995, Argonne 1994, Tucson in 1991, and the Polarized Collider Workshop at Penn State in 1990. As noted last year, the Center provides a home for combined work on spin by theorists, experimenters, and accelerator physicists. This proceedings, as last year, is a compilation of 1 page summaries and 5 selected transparencies for each speaker. It is designed to be available soon after the workshop is completed. Speakers are welcome to include web or other references for additional material. The RHIC spin program and RHIC are rapidly becoming reality. RHIC has completed its first commissioning run, as described here by Steve Peggs. The first Siberian Snake for spin has been completed and is being installed in RHIC. A new polarized source from KEK and Triumf with over 1 milliampere of polarized H minus is being installed, described by Anatoli Zelenski. They have had a successful test of a new polarimeter for RHIC, described by Kazu Kurita and Haixin Huang. Spin commissioning is expected next spring (2000), and the first physics run for spin is anticipated for spring 2001. The purpose of the workshop is to get everyone together about once per year and discuss goals of the spin program, progress, problems, and new ideas. They also have many separate regular forums on spin. There are spin discussion sessions every Tuesday, now organized by Naohito Saito and Werner Vogelsang. The spin discussion schedule and copies of presentations are posted on http://riksg01.rhic.bnl.gov/rsc. Speakers and other spinners are encouraged to come to BNL and to lead a discussion on your favorite idea. They also have regular polarimeter and snake meetings on alternate Thursdays, led by Bill McGahern, the lead engineer for the accelerator spin effort

NC-6301, a polymeric micelle rationally optimized for effective release of docetaxel, is potent but is less toxic than native docetaxel in vivo

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Harada M

2012-05-01

Full Text Available Mitsunori Harada,1 Caname Iwata,2 Hiroyuki Saito,1 Kenta Ishii,1 Tatsuyuki Hayashi,1 Masakazu Yashiro,3 Kosei Hirakawa,3 Kohei Miyazono,2 Yasuki Kato,1 Mitsunobu R Kano21Research Division, NanoCarrier Co, Ltd, Chiba, Japan; 2Department of Molecular Pathology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan; 3Department of Surgical Oncology, Osaka City University, Osaka, JapanAbstract: Drug release rate is an important factor in determining efficacy and toxicity of nanoscale drug delivery systems. However, optimization of the release rate in polymeric micellar nanoscale drug delivery systems has not been fully investigated. In this study NC-6301, a poly(ethylene glycol-poly(aspartate block copolymer with docetaxel (DTX covalently bound via ester link, was synthesized with various numbers of DTX molecules bound to the polymer backbone. The number of DTX molecules was determined up to 14 to achieve an optimal release rate, based upon the authors' own pharmacokinetic model using known patient data. Efficacy and toxicity of the formulation was then tested in animals. When administered three times at 4-day intervals, the maximum tolerated doses of NC-6301 and native DTX were 50 and 10 mg/kg, respectively, in nude mice. Tissue distribution studies of NC-6301 in mice at 50 mg/kg revealed prolonged release of free DTX in the tumor for at least 120 hours, thus supporting its effectiveness. Furthermore, in cynomolgus monkeys, NC-6301 at 6 mg/kg three times at 2-week intervals showed marginal toxicity, whereas native DTX, at 3 mg/kg with the same schedule, induced significant decrease of food consumption and neutrophil count. NC-6301 at 50 mg/kg in mice also regressed a xenografted tumor of MDA-MB-231 human breast cancer. Native DTX, on the other hand, produced only transient and slight regression of the same tumor xenograft. NC-6301 also significantly inhibited growth of OCUM-2MLN human scirrhous gastric carcinoma in an orthotopic mouse

O Electromagnetic Power Waves and Power Density Components.

Science.gov (United States)

Petzold, Donald Wayne

1980-12-01

and reverse power density vectors and which will be shown to be associated with the total electric and magnetic field energy densities existing at a local point will also be introduced. These local forward and reverse power density vectors may be integrated over a surface to determine the forward and reverse powers and from these results problems related to maximum power transfer or efficiency of electromagnetic energy transmission in space may be studied in a manner similar to that presently being done with transmission lines, wave guides, and more recently with two port multiport lumped parameter systems. These new forward and reverse power density vectors at a point in space are analogous to the forward and revoltages or currents and power waves as used with the transmission line, waveguide, or port. These power wave vectors in space are a generalization of the power waves as developed by Penfield, Youla, and Kurokawa and used with the scattering parameters associated with transmission lines, waveguides and ports.

Biological responses according to the shape and size of carbon nanotubes in BEAS-2B and MESO-1 cells

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Haniu H

2014-04-01

Full Text Available Hisao Haniu,1,2 Naoto Saito,2,3 Yoshikazu Matsuda,4 Tamotsu Tsukahara,5 Yuki Usui,1,6,7 Kayo Maruyama,2,3 Seiji Takanashi,1 Kaoru Aoki,1 Shinsuke Kobayashi,1 Hiroki Nomura,1 Manabu Tanaka,1 Masanori Okamoto,1 Hiroyuki Kato1 1Department of Orthopaedic Surgery, Shinshu University School of Medicine, Nagano, Japan; 2Insutitute for Biomedical Sciences, Shinshu University, Nagano, Japan; 3Department of Applied Physical Therapy, Shinshu University School of Health Sciences, Nagano, Japan; 4Clinical Pharmacology Educational Center, Nihon Pharmaceutical University, Saitama, Japan; 5Department of Hematology and Immunology, Kanazawa Medical University, Ishikawa, Japan; 6Research Center for Exotic Nanocarbons, Shinshu University, Nagano, Japan; 7Aizawa Hospital, Sports Medicine Center, Nagano, Japan Abstract: This study aimed to investigate the influence of the shape and size of multi-walled carbon nanotubes (MWCNTs and cup-stacked carbon nanotubes (CSCNTs on biological responses in vitro. Three types of MWCNTs – VGCF®-X, VGCF®-S, and VGCF® (vapor grown carbon fibers; with diameters of 15, 80, and 150 nm, respectively – and three CSCNTs of different lengths (CS-L, 20–80 µm; CS-S, 0.5–20 µm; and CS-M, of intermediate length were tested. Human bronchial epithelial (BEAS-2B and malignant pleural mesothelioma cells were exposed to the CNTs (1–50 µg/mL, and cell viability, permeability, uptake, total reactive oxygen species/superoxide production, and intracellular acidity were measured. CSCNTs were less toxic than MWCNTs in both cell types over a 24-hour exposure period. The cytotoxicity of endocytosed MWCNTs varied according to cell type/size, while that of CSCNTs depended on tube length irrespective of cell type. CNT diameter and length influenced cell aggregation and injury extent. Intracellular acidity increased independently of lysosomal activity along with the number of vacuoles in BEAS-2B cells exposed for 24 hours to either CNT

Chemisorption of Na on the Ti Nanoparticle surface and its effects on the Na-H{sub 2}O reaction reactivity

Energy Technology Data Exchange (ETDEWEB)

Kim, Soo Jae; Park, Gunyeop; Baek, Jehyun; Park, Hyun Sun [POSTECH, Pohang (Korea, Republic of); Kim, Moo Hwan [Korea institute of Nuclear Safety, Daejeon (Korea, Republic of)

2015-10-15

� at t < 1s from Saito,J-i et al experimental data within η{sub error}=8% and Park,G et al experimental data within η{sub error}=104%. Large discrepancy between the model and experiment results at Park,G et al, can be assumed to the error of C{sub NP,Interface} evaluation.

Enterococcus faecalis Responds to Individual Exogenous Fatty Acids Independently of Their Degree of Saturation or Chain Length.

Science.gov (United States)

Saito, Holly E; Harp, John R; Fozo, Elizabeth M

2018-01-01

, thereby altering its membrane composition. In turn, the organism is better able to survive membrane-damaging agents, including the antibiotic daptomycin. We examined fatty acids commonly found in serum and those normally produced by E. faecalis to determine which fatty acids can induce protection from membrane damage. Supplementation with individual fatty acids produced a myriad of different effects on cellular growth, morphology, and stress response. However, only host-derived unsaturated fatty acids provided stress protection. Future studies are aimed at understanding how these specific fatty acids induce protection from membrane damage. Copyright © 2017 Saito et al.

A randomized, double-blind study of hydromorphone hydrochloride extended-release tablets versus oxycodone hydrochloride extended-release tablets for cancer pain: efficacy and safety in Japanese cancer patients (EXHEAL: a Phase III study of EXtended-release HydromorphonE for cAncer pain reLief

Directory of Open Access Journals (Sweden)

Inoue S

2017-08-01

Full Text Available Satoshi Inoue,1 Yoji Saito,2 Satoru Tsuneto,3 Etsuko Aruga,4 Azusa Ide,1 Yasuyuki Kakurai5 1Clinical Development Department, R&D Division, Daiichi Sankyo, Tokyo,2Department of Anesthesiology, Faculty of Medicine, Shimane University, Shimane, 3Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, 4Department of Palliative Medicine, School of Medicine, Teikyo University, Tokyo, 5Biostatistics and Data Management Department, R&D Division, Daiichi Sankyo, Tokyo, Japan Background: In Japan, there are limited options for switching opioid analgesics. Hydromorphone is an opioid analgesic that is routinely used instead of morphine for cancer pain; however, it is not yet available in Japan. The aim of this study was to assess the efficacy and safety of hydromorphone (DS-7113b extended-release tablets in opioid-naïve patients with cancer pain not relieved by non-opioid analgesics.Subjects and methods: This was a multicenter, randomized, double-blind, parallel-group trial. A double-dummy method was used for blinding. Each randomized subject received either hydromorphone extended-release tablets plus placebo oxycodone hydrochloride extended-release tablets 4 mg/day (n=88 or placebo hydromorphone extended-release tablets plus oxycodone hydrochloride extended-release tablets 10 mg/day (n=93 orally for 7 days (once-daily dosing for hydromorphone and twice-daily dosing for oxycodone. The doses were adjusted as necessary. Efficacy was evaluated by change in visual analog scale (VAS score from baseline to completion of treatment.Results: The between-group difference in least squares mean changes in VAS score from baseline to completion or discontinuation of treatment was −0.4 mm (95% CI −5.9 to 5 mm by analysis of covariance where the baseline VAS score was used as a covariate. The upper limit of the 95% CI was below 10 mm, which was predefined as the noninferiority limit. This verified the noninferiority of hydromorphone tablets

Conservative treatment for late-onset bleb leaks after trabeculectomy with mitomycin C in patients with ocular surface disease

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Sagara H

2012-08-01

Full Text Available Hideto Sagara,1,2 Tomohiro Iida,2,3 Kimimori Saito,4 Hiroki Noji,2 Masashi Ogasawara,2 Hiroshi Oyamada21The Marui Eye Clinic, Fukushima, 2Department of Ophthalmology, Fukushima Medical University School of Medicine, Fukushima, 3Tokyo Women's Medical University, Tokyo, 4Matuki Eye Clinic, Fukushima, JapanBackground: Sodium hyaluronate and autologous serum eye drops are used to treat ocular surface disease (OSD and are reported to prevent and treat late-onset bleb leaks following trabeculectomy with mitomycin C. In this study, we evaluated the efficacy of a combination of sodium hyaluronate and autologous serum eye drops and treatment for obstructive meibomian gland dysfunction as a therapy for late-onset bleb leaks after trabeculectomy with mitomycin C.Methods: This was a retrospective, interventional, nonsimultaneous study of 12 subjects (12 eyes of mean age of 64.3 ± 18.3 years with OSD and apparent late-onset bleb leaks following trabeculectomy with mitomycin C between 1998 and 2008. We compared patients diagnosed with leakages before July 2005, who had been treated with separate eye drop solutions containing 0.1% sodium hyaluronate, 50% autologous serum, and 0.3% ofloxacin (sodium hyaluronate and autologous serum group, n = 7, with patients diagnosed from August 2005 to December 2008, who were treated with a combination of eye drops (0.1% sodium hyaluronate, 50% autologous serum, and 0.08% levofloxacin hydrate and eyelid massage and warm compresses for obstructive meibomian gland dysfunction (combination eye drop group, n = 5.Results: Leakage was resolved in one patient (14.3% in the separately treated sodium hyaluronate and autologous serum eye drop group and in five patients (100% in the combination eye drop group (P = 0.015. The period after resolution of leakage with conservative treatment was 23 months in the one eye in the sodium hyaluronate and autologous serum group and 36–61 (mean 52.4 ± 10.1 months in the five eyes in the

Insomnia in patients on hemodialysis for a short versus long duration

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Tomita T

2016-09-01

Full Text Available Tetsu Tomita,1 Norio Yasui-Furukori,1 Masaki Oka,1 Takaaki Shimizu,2 Aya Nagashima,2 Kento Mitsuhashi,2 Hisao Saito,3 Kazuhiko Nakamura1 1Department of Neuropsychiatry, Graduate School of Medicine, 2School of Medicine, Hirosaki University, 3Department of Urology, Oyokyo Kidney Research Institute, Hirosaki, Japan Background: Many studies have investigated insomnia and the factors associated with this condition in hemodialysis (HD patients, although the influence of HD duration has not been thoroughly investigated. In the present study, we investigated the factors, especially the duration of HD, associated with insomnia in HD patients.Patients and methods: A total of 138 patients undergoing HD were recruited, and the Japanese version of the Pittsburgh Sleep Quality Index (PSQI was used to assess the quality of sleep. Subjects with a total PSQI score up to 4 and those with a score of at least 5 were identified as normal subjects and subjects with insomnia, respectively. Additionally, we assessed restless legs syndrome, depression using the Center for Epidemiologic Studies Depression Scale, and health-related quality of life (QOL using the Short Form 8 Health Survey. We divided the subjects into two groups according to the median HD duration.Results: The prevalence rate of insomnia was 54.3% among all the subjects. Twenty-one subjects (15.2% had depression, 26 (18.8% had restless legs syndrome, and 75 (54.3% had insomnia. The median HD duration was 4 years. The scores of components 1 and 4 of the PSQI, subjective sleep quality and habitual sleep efficiency, did not show a significant difference between the normal and insomnia groups. The score of component 7, daytime dysfunction, showed a significant difference between the short and long HD duration groups. In multiple regression analysis, the score of the Short Form 8 Health Survey showed a significant association with the PSQI score in the long HD duration group, but no variable showed a

Development and evaluation of a self-efficacy instrument for Japanese sleep apnea patients receiving continuous positive airway pressure treatment

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Saito A

2015-01-01

Full Text Available Ayako Saito,1 Shigeko Kojima,2 Fumihiko Sasaki,3 Masamichi Hayashi,4 Yuki Mieno,4 Hiroki Sakakibara,5 Shuji Hashimoto1 1Department of Hygiene, School of Medicine, Fujita Health University, Toyoake, Japan; 2Department of Rehabilitation, Faculty of Health Sciences, Nihon Fukushi University, Handa, Japan; 3SDB Research Laboratory, Takaoka Clinic, Nagoya, Japan; 4Department of Internal Medicine, Division of Respiratory Medicine and Clinical Allergy, Fujita Health University, Toyoake, Japan; 5Tokushige Kokyuki Clinic, Nagoya, Japan Abstract: The purpose of this study was to develop and evaluate a self-efficacy instrument for Japanese obstructive sleep apnea (OSA patients treated with continuous positive airway pressure (CPAP. Analyzed subjects were 653 Japanese OSA patients (619 males and 34 females treated with CPAP at a sleep laboratory in a respiratory clinic in a Japanese city. Based on Bandura's social cognitive theory, the CPAP Self-Efficacy Questionnaire for Sleep Apnea in Japanese (CSESA-J was developed by a focus group of experts, using a group interview of OSA patients for the items of two previous self-efficacy scales for Western sleep apnea patients receiving CPAP treatment. CSESA-J has two subscales, one for self-efficacy and the other for outcome expectancy, and consists of a total of 15 items. Content validity was confirmed by the focus group. Confirmatory factor analysis showed that the factor loadings of self-efficacy and outcome expectancy were 0.47–0.76 and 0.41–0.92, respectively, for the corresponding items. CSESA-J had a significant but weak positive association with the General Self-Efficacy Scale, and a strong positive association with “Self-efficacy scale on health behavior in patients with chronic disease.” Cronbach’s alpha coefficient was 0.85 for the self-efficacy subscale and 0.89 for the outcome expectancy subscale. The intraclass correlation coefficient using data from the first and second measurements with

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2013-01-01

Full Text Available Ministério da EducaçãoSecretaria de Educação Profissional e TecnológicaInstituto Federal de Educação, Ciência e Tecnologia Fluminense Reitor Luiz Augusto Caldas Pereira Pró-Reitor de Ensino Carlos Márcio Lima Pró-Reitor de Pesquisa e Inovação José Augusto Ferreira da Silva Pró-Reitora de Extensão Paula Aparecida Martins Borges BastosEditora-Chefe Inez Barcellos de Andrade Coordenação Editorial do Boletim Maria Inês Paes Ferreira Conselho Editorial Conselho Consultivo Edinalda Almeida da SilvaHelvia Pereira Pinto BastosJefferson Manhães de AzevedoLuiz de Pinedo Quinto JuniorMaria Amelia Ayd CorrêaMaria Inês Paes FerreiraPedro de Azevedo Castelo BrancoRegina Coeli Martins AquinoRogério Atem de CarvalhoRomeu e Silva NetoSaid Sérgio Martins AuattSalvador TavaresSergio VasconcelosSilvia Lúcia dos Santos BarretoSynthio Vieira de AlmeidaVania Cristina Alexandrino BernardoVicente de Paulo Santos OliveiraWander Gomes Ney Adalberto Cardoso (IESP/UERJAntonio Carlos Secchin (UFRJAntônio José da Silva Neto (IPRJ/UERJAsterio Kiyoshi Tanaka (UNIRIO e UFRJErica Maria Pellegrini Caramaschi (UFRJFernando Benedicto Mainier (UFFFernando Pruski (UFVFrancisco de Assis Esteves (UFRJGaudêncio Frigotto (UFFHamilton Jorge de Azevedo (UFRRJHelder Gomes Costa (UFFIná Elias de Castro (UFRJJader Lugon Junior (IFF/UERJ/SENAIJanete Bolite Frant (UNIBANJosé Abdallah Helayël-Neto (CBPF/MCTMiriam Fontelle (UNIFLU e UNESARodrigo Valente Serra (ANPRonaldo Pinheiro da Rocha Paranhos (UENFSérgio Arruda de Moura (UENFVera Lucia Marques da Silva (FBPNVirgínia Maria Gomes de Mattos Fontes (UFF Organizadores deste númeroMaria Inês Paes FerreiraJader Lugon JuniorLuiz de Pinedo Quinto JúniorLuiz Felipe Umbelino dos SantosBolsista de Iniciação CientíficaCamilla Cardoso da Costa Revisão de Língua Portuguesa e Inglesa Edson Carlos Nascimento Projeto Gráfico André da Silva CruzEric Moreira Carvalho Diagramação Cláudia Marcia Alves Ferreira

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2013-07-01

Full Text Available Ministério da EducaçãoSecretaria de Educação Profissional e TecnológicaInstituto Federal de Educação, Ciência e Tecnologia Fluminense Reitor Luiz Augusto Caldas Pereira Pró-Reitor de Ensino Carlos Márcio Lima Pró-Reitor de Pesquisa e Inovação José Augusto Ferreira da Silva Pró-Reitora de Extensão Paula Aparecida Martins Borges BastosEditora-Chefe Inez Barcellos de Andrade Coordenação Editorial do Boletim Maria Inês Paes Ferreira Conselho Editorial Conselho Consultivo Edinalda Almeida da SilvaHelvia Pereira Pinto BastosJefferson Manhães de AzevedoLuiz de Pinedo Quinto JuniorMaria Amelia Ayd CorrêaMaria Inês Paes FerreiraPedro de Azevedo Castelo BrancoRegina Coeli Martins AquinoRogério Atem de CarvalhoRomeu e Silva NetoSaid Sérgio Martins AuattSalvador TavaresSergio VasconcelosSilvia Lúcia dos Santos BarretoSynthio Vieira de AlmeidaVania Cristina Alexandrino BernardoVicente de Paulo Santos OliveiraWander Gomes Ney Adalberto Cardoso (IESP/UERJAntonio Carlos Secchin (UFRJAntônio José da Silva Neto (IPRJ/UERJAsterio Kiyoshi Tanaka (UNIRIO e UFRJErica Maria Pellegrini Caramaschi (UFRJFernando Benedicto Mainier (UFFFernando Pruski (UFVFrancisco de Assis Esteves (UFRJGaudêncio Frigotto (UFFHamilton Jorge de Azevedo (UFRRJHelder Gomes Costa (UFFIná Elias de Castro (UFRJJader Lugon Junior (IFF/UERJ/SENAIJanete Bolite Frant (UNIBANJosé Abdallah Helayël-Neto (CBPF/MCTMiriam Fontelle (UNIFLU e UNESARodrigo Valente Serra (ANPRonaldo Pinheiro da Rocha Paranhos (UENFSérgio Arruda de Moura (UENFVera Lucia Marques da Silva (FBPNVirgínia Maria Gomes de Mattos Fontes (UFF Organizadores deste númeroMaria Inês Paes FerreiraJader Lugon JuniorLuiz de Pinedo Quinto JúniorBolsista de Iniciação CientíficaCamilla Cardoso da Costa Revisão de Língua Portuguesa e Inglesa Edson Carlos NascimentoIsabela Bastos de CarvalhoKissila Ferreira de SouzaPriscila Matos MonkenRosângela Caldas Projeto Gráfico André da Silva CruzEric Moreira

Single Molecule Detection in Living Biological Cells using Carbon Nanotube Optical Probes

Science.gov (United States)

Strano, Michael

2009-03-01

osmotic pressure gradients will be discussed, as well as its potential as a unique transduction mechanism for a new class of implantable sensors. [4pt] [1] Saito, R., Dresselhaus, G. & Dresselhaus, M. S. Physical Properties of Carbon Nanotubes (Imperial College Press, London, 1998). [0pt] [2] Barone, P. W., Baik, S., Heller, D. A. & Strano, M. S. Near-Infrared Optical Sensors Based on Single-Walled Carbon Nanotubes. Nature Materials 4, 86-92 (2005). [0pt] [3] Jeng, E. S., Moll, A. E., Roy, A. C., Gastala, J. B. & Strano, M. S. Detection of DNA hybridization using the near infrared band-gap fluorescence of single-walled carbon nanotubes. Nano Letters 6, 371-375 (2006). [0pt] [4] Heller, D. A. et al. Optical detection of DNA conformational polymorphism on single-walled carbon nanotubes. Science 311, 508-511 (2006).

Core dynamics analysis for reactivity insertion and loss of coolant flow tests using the HTTR

International Nuclear Information System (INIS)

Takamatsu, Kuniyoshi; Nakagawa, Shigeaki; Takeda, Tetsuaki

2007-01-01

The High Temperature engineering Test Reactor (HTTR) is a graphite-moderated and a gas-cooled reactor with a thermal power of 30 MW and a reactor outlet coolant temperature of 950degC (SAITO, 1994). Safety demonstration tests using the HTTR are in progress to verify its inherent safety features and improve the safety technology and design methodology for High-Temperature Gas-cooled Reactors (HTGRs) (TACHIBANA 2002) (NAKAGAWA 2004). The reactivity insertion test is one of the safety demonstration tests for the HTTR. This test simulates the rapid increase in the reactor power by withdrawing the control rod without operating the reactor power control system. In addition, the loss of coolant flow tests has been conducted to simulate the rapid decrease in the reactor power by tripping one, two or all out of three gas circulators. The experimental results have revealed the inherent safety features of HTGRs, such as the negative reactivity feedback effect. The numerical analysis code, which was named ACCORD (TAKAMATSU 2006), was developed to analyze the reactor dynamics including the flow behavior in the HTTR core. We used a conventional method, namely, a one-dimensional flow channel model and reactor kinetics model with a single temperature coefficient, taking into account the temperature changes in the core. However, a slight difference between the analytical and experimental results was observed. Therefore, we have modified this code to use a model with four parallel channels and twenty temperature coefficients in the core. Furthermore, we added another analytical model of the core for calculating the heat conduction between the fuel channels and the core in the case of the loss of coolant flow tests. This paper describes the validation results for the newly developed code using the experimental results of the reactivity insertion test as well as the loss of coolant flow tests by tripping one or two out of three gas circulators. Finally, the pre-analytical result of

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2010-05-01

Full Text Available Ministério da EducaçãoSecretaria de Educação Profissional e TecnológicaInstituto Federal de Educação, Ciência e Tecnologia Fluminense Reitora Cibele Daher Botelho Monteiro Pró-Reitora de Ensino Fabíola de Amério Ney Silva Pró-Reitor de Pesquisa e Inovação Hélio Gomes Filho Pró-Reitor de Extensão Eugênio Ferreira Naegele da Silva Pró-Reitor de Desenvolvimento Institucional Roberto Moraes Pessanha Editora-chefe Inez Barcellos de AndradeCoordenação Editorial do Boletim Maria Inês Paes Ferreira Conselho Editorial Conselho Consultivo Desiely Silva GusmãoEdinalda Almeida da SilvaHelvia Pereira Pinto BastosInez Barcellos de AndradeJefferson Manhães de AzevedoLuiz de Pinedo Quinto JuniorMaria Amelia Ayd CorrêaMaria Inês Paes FerreiraPedro de Azevedo Castelo BrancoRegina Coeli Martins AquinoRogério Atem de CarvalhoRomeu e Silva NetoSaid Sérgio Martins AuattSalvador TavaresSergio VasconcelosSilvia Lúcia dos Santos BarretoSynthio Vieira de AlmeidaVania Cristina Alexandrino BernardoVicente de Paulo Santos OliveiraWander Gomes Ney Adalberto Cardoso (IESP/UERJAntonio Carlos Secchin (UFRJAntônio José da Silva Neto (IPRJ/UERJAsterio Kiyoshi Tanaka (UNIRIO e UFRJErica Maria Pellegrini Caramaschi (UFRJFernando Benedicto Mainier (UFFFernando Pruski (UFVFrancisco de Assis Esteves (UFRJGaudêncio Frigotto (UFFHamilton Jorge de Azevedo (UFRRJHelder Gomes Costa (UFFIná Elias de Castro (UFRJJader Lugon Junior (IFF/UERJ/SENAIJanete Bolite Frant (UNIBANJosé Abdallah Helayël-Neto (CBPF/MCTMiriam Fontelle (UNIFLU e UNESARodrigo Valente Serra (ANPRonaldo Pinheiro da Rocha Paranhos (UENFSérgio Arruda de Moura (UENFVera Lucia Marques da Silva (FBPNVirgínia Maria Gomes de Mattos Fontes (UFF Apoio TécnicoCarlos David PascoDenia Cristina da Silva BarretoGisele Carvalho da Silva Costa Nogueira Bolsista de Iniciação CientíficaJáder da Mota SiqueiraJúlio Fontoura Gonçalves de LimaSamara Melo RodriguesWanessa Alves Duarte Revisão de Texto

Proceedings of the 8th International Symposium on Foundations of Quantum Mechanics in the Light of New Technology

Science.gov (United States)

Ishioka, Sachio; Fujikawa, Kazuo

2006-06-01

.]. Coalescence and rearrangement of vortices in mesoscopic superconductors / A. Kanda ... [et al.]. Superconductivity in topologically nontrivial spaces / M. Hayashi ... [et al.]. DC-SQUID ratchet using atomic point contact / Y. Ootuka, H. Miyazaki, A. Kanda. Superconducting wire network under spatially modulated magnetic field / H. Sano ... [et al.]. Simple and stable control of mechanical break junction for the study of superconducting atomic point contact / H. Miyazaki ... [et al.]. Critical currents in quasiperiodic pinning arrays: one-dimensional chains and Penrose lattices / V. R. Misko, S. Savel'ev, F. Nori. Macroscopic quantum tunneling in high-Tc superconductor Josephson junctions / S. Kawabata -- Novel properties of carbon nanotubes. Carbon nanotubes and unique transport properties: importance of symmetry and channel number / T. Ando. Optical processes in single-walled carbon nanotubes threaded by a magnetic flux / J. Kono ... [et al.]. Non-equilibrium transport through a single-walled carbon nanotube with highly transparent coupling to reservoirs / P. Recher, N. Y. Kim, Y. Yamamoto -- Novel properties of nano-systems. Transport properties in low dimensional artificial lattice of gold nano-particles / S. Saito ... [et al.]. First principles study of dihydride-chain structures on H-terminated Si(100) surface / Y. Suwa ... [et al.]. Electrical property of Ag nanowires fabricated on hydrogen-terminated Si(100) surface / M. Fujimori, S. Heike, T. Hashizume. Effect of environment on ionization of excited atoms embedded in a solid-state cavity / M. Ando ... [et al.]. Development of universal virtual spectroscope for optoelectronics research: first principles software replacing dielectric constant measurements / T. Hamada ... [et al.]. Quantum Nernst effect / H Nakamura, N. Hatano, R. Shirasaki -- Precise measurements. Quantum phenomena visualized using electron waves / A. Tonomura. An optical lattice clock: ultrastable atomic clock with engineered perturbation / H. Katori

In-situ measurements of ice nucleating particles with FINCH (Fast Ice Nucleus Chamber)

Science.gov (United States)

Kohl, Rebecca; Frank, Fabian; Curtius, Joachim; Rose, Diana

2017-04-01

., Wetter, T., Klein, H., and Bingemer, H.: The fast Ice Nucleus chamber FINCH, Atmos. Res., 90, 180-186, 10.1016/j.atmosres.2008.02.008, 2008. Bundke, U., Reimann, B., Nillius, B., Jaenicke, R., and Bingemer, H.: Development of a Bioaerosol single particle detector (BIO IN) for the Fast Ice Nucleus CHamber FINCH, Atmos. Meas. Tech., 3, 263-271, doi:10.5194/amt-3-263-2010, 2010. DeMott, P. J., Moehler, O., Stetzer, O., Vali, G., Levin, Z., Petters, M. D., Murakami, M., Leisner, T., Bundke, U., Klein, H., Kanji, Z. A., Cotton, R., Jones, H., Benz, S., Brinkmann, M., Rzesanke, D., Saathoff, H., Nicolet, M., Saito, A., Nillius, B., Bingemer, H., Abbatt, J., Ardon, K., Ganor, E., Georgakopoulos, D. G., and Saunders, C.: Resurgence in ice nuclei measurement research, Bulletin of the American Meteorological Society, 92, 1623-1635, 10.1175/bams-d-10-3119.1, 2011.

Projection of the change in future extremes over Japan using a cloud-resolving model: (2) Precipitation Extremes and the results of the NHM-1km experiments

Science.gov (United States)

Kanada, S.; Nakano, M.; Nakamura, M.; Hayashi, S.; Kato, T.; Kurihara, K.; Sasaki, H.; Uchiyama, T.; Aranami, K.; Honda, Y.; Kitoh, A.

2008-12-01

In order to study changes in the regional climate in the vicinity of Japan during the summer rainy season due to global warming, experiments by a semi-cloud resolving non-hydrostatic model with a horizontal resolution of 5km (NHM-5km) have been conducted from June to October by nesting within the results of the 10-year time-integrated experiments using a hydrostatic atmospheric general circulation model with a horizontal grid of 20 km (AGCM-20km: TL959L60) for the present and future up to the year 2100. A non-hydrostatic model developed by the Japan Meteorological Agency (JMA) (JMA-NHM; Saito et al. 2001, 2006) was adopted. Detailed descriptions of the NHM-5km are shown by the poster of Nakano et al. Our results show that rainy days over most of the Japanese Islands will decrease in June and July and increase in August and September in the future climate. Especially, remarkable increases in intense precipitations such as larger than 150 - 300 mm/day are projected from the present to future climate. The 90th percentiles of regional largest values among maximum daily precipitations (R-MDPs) grow 156 to 207 mm/day in the present and future climates, respectively. It is well-known that the horizontal distribution of precipitation, especially the heavy rainfall in the vicinity of Japan, much depends on the topography. Therefore, higher resolution experiments by a cloud-resolving model with a horizontal resolution of 1km (NHM-1km) are one-way nested within the results of NHM-5km. The basic frame and design of the NHM-1km is the same as those of the NHM-5km, but the topography is finer and no cumulus parameterization is used in the NHM-1km experiments. The NHM-1km, which treats the convection and cloud microphysics explicitly, can represent not only horizontal distributions of rainfall in detail but also the 3-dimensional structures of meso-beta-scale convective systems (MCSs). Because of the limitation of computation resources, only heavy rainfall events that rank in top

Hospital-based child protection teams that care for parents who abuse or neglect their children recognize the need for multidisciplinary collaborative practice involving perinatal care and mental health professionals: a questionnaire survey conducted in Japan

Directory of Open Access Journals (Sweden)

Okato A

2018-02-01

Full Text Available Ayumi Okato,1 Tasuku Hashimoto,1 Mami Tanaka,2 Masumi Tachibana,1 Akira Machizawa,3 Jun Okayama,4 Mamiko Endo,5 Masayoshi Senda,6,7 Naoki Saito,5,7 Masaomi Iyo1 1Department of Psychiatry, Graduate School of Medicine, Chiba University, 2Division of Clinical Study on Juvenile Delinquency, Center for Forensic Mental Health, Chiba University, 3Department of Psychiatry, Chiba University Hospital, 4Department of Reproductive Medicine, Graduate School of Medicine, Chiba University, 5Department of Pediatrics, Graduate School of Medicine, Chiba University, 6Department of Pediatrics, Asahi General Hospital, 7Division of Clinical Forensic Medicine, Education and Research Center of Legal Medicine, Chiba University, Chiba, Japan Background: Child abuse and/or neglect is a serious issue, and in many cases, parents are the perpetrators. Hospital-based child protection teams (CPTs play pivotal roles in the management of not only abused and/or neglected children but also of their parents; this is generally conducted through multidisciplinary practice. The aim of this study is to survey hospital-based CPT members to determine the professions they perceive to be most applicable to participation in CPTs. Participants and methods: The participants were members of CPTs affiliated with hospitals that had pediatric emergency departments and which were located in Chiba Prefecture; specifically, 114 CPT members from 23 hospitals responded to this survey. The two main questionnaire items concerned are as follows: 1 each respondent’s evaluation of conducting assessments, providing support, and implementing multidisciplinary collaborative practice in the treatment of abusive and negligent parents, and 2 each CPT member’s opinion on the professions that are most important for CPT activities. An exploratory factor analysis (EFA was performed to explore the factor structure of the data, and a correlation analysis was performed using the result obtained. Results: The EFA

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2015-02-01

Full Text Available Ministério da EducaçãoSecretaria de Educação Profissional e TecnológicaInstituto Federal de Educação, Ciência e Tecnologia FluminenseReitorLuiz Augusto Caldas PereiraPró-Reitor de EnsinoCarlos Márcio LimaPró-Reitor de Pesquisa e InovaçãoJosé Augusto Ferreira da SilvaPró-Reitora de ExtensãoPaula Aparecida Martins Borges BastosPró-Reitora de Desenvolvimento InstitucionalAna Lúcia CampinhoCoordenadora da Essentia EditoraKíssila da Conceição RibeiroConselho EditorialConselho ConsultivoDesiely Silva GusmãoEdinalda Almeida da SilvaHelvia Pereira Pinto BastosInez Barcellos de AndradeJefferson Manhães de AzevedoKíssila da Conceição RibeiroLuiz de Pinedo Quinto JuniorMaria Amelia Ayd CorrêaMaria Inês Paes FerreiraPedro de Azevedo Castelo BrancoRegina Coeli Martins AquinoRogério Atem de CarvalhoRomeu e Silva NetoSaid Sérgio Martins AuattSalvador TavaresSergio VasconcelosSilvia Lúcia dos Santos BarretoSynthio Vieira de AlmeidaVania Cristina Alexandrino BernardoVicente de Paulo Santos OliveiraWander Gomes NeyAdalberto Cardoso (IESP/UERJAntonio Carlos Secchin (UFRJAntônio José da Silva Neto (IPRJ/UERJAsterio Kiyoshi Tanaka (UNIRIO e UFRJErica Maria Pellegrini Caramaschi (UFRJFernando Benedicto Mainier (UFFFernando Pruski (UFVFrancisco de Assis Esteves (UFRJGaudêncio Frigotto (UFFHamilton Jorge de Azevedo (UFRRJHelder Gomes Costa (UFFIná Elias de Castro (UFRJJader Lugon Junior (IFF/UERJ/SENAIJanete Bolite Frant (UNIBANJosé Abdallah Helayël-Neto (CBPF/MCTRodrigo Valente Serra (ANPRonaldo Pinheiro da Rocha Paranhos (UENFSérgio Arruda de Moura (UENFVera Lucia Marques da Silva (FBPNVirgínia Maria Gomes de Mattos Fontes (UFFEquipe EditorialRevisão de Língua PortuguesaEdson Carlos NascimentoDenise Rena HaddadRevisão de Língua InglesaHélvia Pereira Pinto BastosCapa, Projeto GráficoAndré da Silva CruzDiagramaçãoCláudia Marcia Alves FerreiraCatalogação e Revisão TécnicaHenrique Barreiros Alves

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2015-05-01

Full Text Available Ministério da EducaçãoSecretaria de Educação Profissional e TecnológicaInstituto Federal de Educação, Ciência e Tecnologia FluminenseReitorLuiz Augusto Caldas PereiraPró-Reitor de EnsinoCarlos Márcio LimaPró-Reitor de Pesquisa e InovaçãoJosé Augusto Ferreira da SilvaPró-Reitora de ExtensãoPaula Aparecida Martins Borges BastosPró-Reitora de Desenvolvimento InstitucionalAna Lúcia CampinhoEditora-chefeKíssila da Conceição RibeiroConselho EditorialConselho ConsultivoDesiely Silva GusmãoEdinalda Maria Almeida da SilvaHelvia Pereira Pinto BastosInez Barcellos de AndradeJefferson Manhães de AzevedoKíssila da Conceição RibeiroLuiz de Pinedo Quinto JuniorMaria Amelia Ayd CorrêaMaria Inês Paes FerreiraPedro de Azevedo Castelo BrancoRegina Coeli Martins AquinoRogério Atem de CarvalhoRomeu e Silva NetoSaid Sérgio Martins AuattSalvador TavaresSergio VasconcelosSilvia Lúcia dos Santos BarretoSynthio Vieira de AlmeidaVania Cristina Alexandrino BernardoVicente de Paulo Santos OliveiraWander Gomes NeyAdalberto Cardoso (IESP/UERJAntonio Carlos Secchin (UFRJAntônio José da Silva Neto (IPRJ/UERJAsterio Kiyoshi Tanaka (UNIRIO e UFRJErica Maria Pellegrini Caramaschi (UFRJFernando Benedicto Mainier (UFFFernando Pruski (UFVFrancisco de Assis Esteves (UFRJGaudêncio Frigotto (UFFHamilton Jorge de Azevedo (UFRRJHelder Gomes Costa (UFFIná Elias de Castro (UFRJJader Lugon Junior (IFF/UERJ/SENAIJanete Bolite Frant (UNIBANJosé Abdallah Helayël-Neto (CBPF/MCTRodrigo Valente Serra (ANPRonaldo Pinheiro da Rocha Paranhos (UENFSérgio Arruda de Moura (UENFVera Lucia Marques da Silva (FBPNVirgínia Maria Gomes de Mattos Fontes (UFFEquipe EditorialRevisão de Língua PortuguesaEdson Carlos NascimentoDenise Rena HaddadRevisão de Língua InglesaHélvia Pereira Pinto BastosCapa, Projeto GráficoAndré da Silva CruzDiagramaçãoCláudia Marcia Alves FerreiraCatalogação e Revisão TécnicaHenrique Barreiros AlvesLogotipoMarcos Antonio Esquef

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2014-08-01

Full Text Available Ministério da EducaçãoSecretaria de Educação Profissional e TecnológicaInstituto Federal de Educação, Ciência e Tecnologia Fluminense Reitor Luiz Augusto Caldas Pereira Pró-Reitor de Ensino Carlos Márcio Lima Pró-Reitor de Pesquisa e Inovação José Augusto Ferreira da Silva Pró-Reitora de Extensão Paula Aparecida Martins Borges Bastos Pró-Reitora de Desenvolvimento Institucional Ana Lúcia Campinho Coordenadora da Essentia Editora Kíssila da Conceição Ribeiro Conselho Editorial Conselho Consultivo Desiely Silva GusmãoEdinalda Almeida da SilvaHelvia Pereira Pinto BastosInez Barcellos de AndradeJefferson Manhães de AzevedoLuiz de Pinedo Quinto JuniorMaria Amelia Ayd CorrêaMaria Inês Paes FerreiraPedro de Azevedo Castelo BrancoRegina Coeli Martins AquinoRogério Atem de CarvalhoRomeu e Silva NetoSaid Sérgio Martins AuattSalvador TavaresSergio VasconcelosSilvia Lúcia dos Santos BarretoSynthio Vieira de AlmeidaVania Cristina Alexandrino BernardoVicente de Paulo Santos OliveiraWander Gomes Ney Adalberto Cardoso (IESP/UERJAntonio Carlos Secchin (UFRJAntônio José da Silva Neto (IPRJ/UERJAsterio Kiyoshi Tanaka (UNIRIO e UFRJErica Maria Pellegrini Caramaschi (UFRJFernando Benedicto Mainier (UFFFernando Pruski (UFVFrancisco de Assis Esteves (UFRJGaudêncio Frigotto (UFFHamilton Jorge de Azevedo (UFRRJHelder Gomes Costa (UFFIná Elias de Castro (UFRJJader Lugon Junior (IFF/UERJ/SENAIJanete Bolite Frant (UNIBANJosé Abdallah Helayël-Neto (CBPF/MCTRodrigo Valente Serra (ANPRonaldo Pinheiro da Rocha Paranhos (UENFSérgio Arruda de Moura (UENFVera Lucia Marques da Silva (FBPNVirgínia Maria Gomes de Mattos Fontes (UFF Equipe Editorial Revisão de Língua Portuguesa Edson Carlos NascimentoIsabela Bastos de CarvalhoKíssila Ferreira de SouzaPriscila Matos MonkenRosângela Caldas Revisão de Língua Inglesa Hélvia Pereira Pinto Bastos Capa, Projeto Gráfico André da Silva Cruz Diagramação Cláudia Marcia Alves FerreiraMariana de

PREFACE: Aerodynamic sound Aerodynamic sound

Science.gov (United States)

Akishita, Sadao

2010-02-01

reduction of bluff-body noise. Xiaoyu Wang and Xiaofeng Sun discuss the interaction of fan stator and acoustic treatments using the transfer element method. S Saito and his colleagues in JAXA report the development of active devices for reducing helicopter noise. The paper by A Tamura and M Tsutahara proposes a brand new methodology for aerodynamic sound by applying the lattice Boltzmann finite difference method. As the method solves the fluctuation of air density directly, it has the advantage of not requiring modeling of the sound generation. M A Langthjem and M Nakano solve the hole-tone feedback cycle in jet flow by a numerical method. Y Ogami and S Akishita propose the application of a line-vortex method to the three-dimensional separated flow from a bluff body. I hope that a second issue on aerodynamic sound will be published in FDR in the not too distant future.

Analysis of a burning fuel on a water sublayer: conditions of triggering mechanism of superheated water explosion ('boilover')

International Nuclear Information System (INIS)

Jordan Y Hristov

2005-01-01

, Kluwer Academic Publishers, Dordrecht, The Netherlands, pp. 167-182; 2. Arai M, Saito K and Altenkirch RA (1990) A study of Boilover I Liquid Pool Fires Supported on Water. Part 1: Effects of a Water Sublayer on Pool Fires, Combustion Science and Technology., v. 71, pp.25-40; 3. Wu N, Backer M, Kolb and Torero JL (1997) Ignition, Flame spread and mass burning characteristics of liquid fuels on a water bed, In: Proc. of 20. Arctic and Marine Oil Spill Program (AMOP) Technical Seminar, Alberta, Canada, Environment Canada, Ottawa, Ontario, June 11-13 1997, vol. 2., pp. 769-793; 4. Koseki H, Kokkala M and Mulholland GW (1991) Experimental Study of Boilover in Crude Oil Fires, Fire Safety Science. Proc. of 3. Int. Symp., Elsevier, London and New York, pp. 865-874 5. Hristov, J.Y., Planas, E., Arnaldos, J, Casal J., Accidental Burning of a Fuel Layer on a Waterbed: A Scale Analysis Study of the Heat Transfer Models Predicting the pre-Boilover Time and Scaling to Published Data, Int. J. Thermal Sciences, 43 (3) (2004) 221-239. (author)

Intestinal absorption, organ distribution, and urinary excretion of the rare sugar D-psicose

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Tsukamoto I

2014-10-01

Full Text Available Ikuko Tsukamoto,1,* Akram Hossain,2,3,* Fuminori Yamaguchi,2 Yuko Hirata,2 Youyi Dong,2 Kazuyo Kamitori,2 Li Sui,2 Machiko Nonaka,2 Masaki Ueno,4 Kazuyuki Nishimoto,5 Hirofumi Suda,5 Kenji Morimoto,6 Tsuyoshi Shimonishi,7,† Madoka Saito,8 Tao Song,9 Ryoji Konishi,1 Masaaki Tokuda2 1Department of Pharmaco-Bio-Informatics, Faculty of Medicine, Kagawa University, Miki, Kagawa, Japan; 2Department of Cell Physiology, Faculty of Medicine, Kagawa University, Kagawa, Japan; 3Matsutani Chemical Industry Co, Ltd, Itami, Japan; 4Department of Inflammation Pathology, Faculty of Medicine, Kagawa University, Kagawa, Japan; 5Division of Radioisotope Research, Life Science Research Center, Kagawa University, Kagawa, Japan; 6Rare Sugar Research Center, Kagawa University, Kagawa, Japan; 7IZUMORING LLC, Miki, Kita, Kagawa, Japan; 8Department of Pharmacy, Okayama University Hospital, Okayama, Japan; 9The First Affiliated Hospital, China Medical University, Shenyang, People’s Republic of China *These authors contributed equally to this work†Tsuyoshi Shimonishi has passed away Background: The purpose of this study was to evaluate intestinal absorption, organ distribution, and urinary elimination of the rare sugar D-psicose, a 3-carbon stereoisomer of D-fructose that is currently being investigated and which has been found to be strongly effective against hyperglycemia and hyperlipidemia. Methods: This study was performed using radioactive D-psicose, which was synthesized enzymatically from radioactive D-allose. Concentrations in whole blood, urine, and organs were measured at different time points until 2 hours after both oral and intravenous administrations and 7 days after a single oral administration (100 mg/kg body weight to Wistar rats. Autoradiography was also performed by injecting 100 mg/kg body weight of 14C-labeled D-psicose or glucose intravenously to C3H mice. Results: Following oral administration, D-psicose easily moved to blood. The maximum blood

Sulfur isotopic fractionation of carbonyl sulfide during degradation by soil bacteria and enzyme

Science.gov (United States)

Kamezaki, Kazuki; Hattori, Shohei; Ogawa, Takahiro; Toyoda, Sakae; Kato, Hiromi; Katayama, Yoko; Yoshida, Naohiro

2017-04-01

OCS, indicating that reaction for OC32S was faster than that for OC33S and OC34S (Kamezaki et al., 2016). Although OCS degradation rates divided by cell numbers were different among strains of the same genus, the isotopic fractionation constants for same genus showed no significant differences. At the presentation, we discuss the mechanism of isotopic fractionation for OCS during degradation by comparing soil bacteria with enzyme. References Asaf, D., Rotenberg, E., Tatarinov, F., Dicken, U., Montzka, S. A., Yakir, D. Nat. Geosci., 6, 186-190, 2013 Campbell, J. E., Carmichael, G. R., Chai, T., Mena-Carrasco, M., Tang, Y., Blake, D. R., Blake, N. J., Vay, S. A., Collatz, G. J., Baker, I., Berry, J. A., Montzka, S. A., Sweeney, C., Schnoor, J. L., Stanier, C. O., Science, 332, 1085-1088, 2008. Hattori, S., Toyoda, A., Toyoda, S., Ishino, S., Ueno, Y., Yoshida, N. Anal. Chem., 87, 477-484, 2015. Ogawa, T., Noguchi, K., Saito, M., Nagahata, Y., Kato, H., Ohtaki, A., Nakayama, H., Dohmae, N., Matsushita, Y., Odaka, M., Yohda, M., Nyunoya, H., Katayama, Y. J. Am. Chem. Soc., 135, 3818-3825, 2013. Kamezaki, K., Hattori, S., Ogawa, T., Toyoda, S., Kato, H., Katayama, Y., Yoshida, N. Environ. Sci. Technol., 50, 3537-3544, 2016.

PREFACE: International Symposium on Non-Equilibrium Soft Matter 2010 International Symposium on Non-Equilibrium Soft Matter 2010

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Kawakatsu, T.; Matsuyama, A.; Ohta, T.; Tanaka, H.; Tanaka, S.

2011-07-01

, Culture, Sports, Science and Technology (MEXT) of Japan. We thank those who contributed to this symposium as well as members of the 'Soft Matter Physics' project for their valuable discussions and collaborations. Non-equilibrium soft matter contents Insights on raft behavior from minimal phenomenological models G Garbès Putzel and M Schick Dynamical membrane curvature instability controlled by intermonolayer friction Anne-Florence Bitbol, Jean-Baptiste Fournier, Miglena I Angelova and Nicolas Puff Numerical investigations of the dynamics of two-component vesicles Takashi Taniguchi, Miho Yanagisawa and Masayuki Imai Asymmetric distribution of cone-shaped lipids in a highly curved bilayer revealed by a small angle neutron scattering technique Y Sakuma, N Urakami, T Taniguchi and M Imai Hydration, phase separation and nonlinear rheology of temperature-sensitive water-soluble polymers Fumihiko Tanaka, Tsuyoshi Koga, Isamu Kaneda and Françoise M Winnik Morphology and rheology of an immiscible polymer blend subjected to a step electric field under shear flow H Orihara, Y Nishimoto, K Aida, Y H Na, T Nagaya and S Ujiie Surfactant-induced friction reduction for hydrogels in the boundary lubrication regime Kosuke Kamada, Hidemitsu Furukawa, Takayuki Kurokawa, Tomohiro Tada, Taiki Tominaga, Yukihiro Nakano and Jian Ping Gong Fabrication and structural analysis of polyrotaxane fibers and films Yasuhiro Sakai, Kentaro Ueda, Naoya Katsuyama, Koji Shimizu, Shunya Sato, Jun Kuroiwa, Jun Araki, Akira Teramoto, Koji Abe, Hideaki Yokoyama and Kohzo Ito Micellization kinetics of diblock copolymers in a homopolymer matrix: a self-consistent field study Raghuram Thiagarajan and David C Morse Hierarchical self-assembly of two-length-scale multiblock copolymers Gerrit ten Brinke, Katja Loos, Ivana Vukovic and Gerrit Gobius du Sart Kaleidoscopic morphologies from ABC star-shaped terpolymers Yushu Matsushita, Kenichi Hayashida, Tomonari Dotera and Atsushi Takano Direct and inverted nematic

PREFACE: Ultrafast and nonlinear optics in carbon nanomaterials

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Kono, Junichiro

2013-02-01

Journal of Physics: Condensed Matter staff for their help, patience and professionalism. Since this is a fast-moving field, there is absolutely no way of presenting definitive answers to all open questions, but we hope that this special section will provide an overview of the current state of knowledge regarding this topic. Furthermore, we hope that the exciting science and technology described in this section will attract and inspire other researchers and students working in related fields to enter into the study of ultrafast and nonlinear optical phenomena in carbon-based nanostructures. Ultrafast and nonlinear optics in carbon nanomaterials contents Ultrafast and nonlinear optics in carbon nanomaterialsJunichiro Kono The impact of pump fluence on carrier relaxation dynamics in optically excited grapheneT Winzer and E Malic Time-resolved spectroscopy on epitaxial graphene in the infrared spectral range: relaxation dynamics and saturation behaviorS Winnerl, F Göttfert, M Mittendorff, H Schneider, M Helm, T Winzer, E Malic, A Knorr, M Orlita, M Potemski, M Sprinkle, C Berger and W A de Heer Nonlinear optics of graphene in a strong magnetic fieldXianghan Yao and Alexey Belyanin Theory of coherent phonons in carbon nanotubes and graphene nanoribbonsG D Sanders, A R T Nugraha, K Sato, J-H Kim3, J Kono3, R Saito and C J Stanton Non-perturbative effects of laser illumination on the electrical properties of graphene nanoribbons Hernán L Calvo, Pablo M Perez-Piskunow, Horacio M Pastawski, Stephan Roche and Luis E F Foa Torres Transient absorption microscopy studies of energy relaxation in graphene oxide thin film Sean Murphy and Libai Huang Femtosecond dynamics of exciton localization: self-trapping from the small to the large polaron limit F X Morrissey, J G Mance, A D Van Pelt and S L Dexheimer

Sulfur isotopic analysis of carbonyl sulfide and its application for biogeochemical cycles

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Hattori, Shohei; Kamezaki, Kazuki; Ogawa, Takahiro; Toyoda, Sakae; Katayama, Yoko; Yoshida, Naohiro

2016-04-01

reaction does not contribute to the MIF signatures observed in sulfate aerosol samples and/or Archaean rock records. At the presentation, we report the comparison of 34ɛ values determined using some strains and the atmospheric implications for the OCS degradation in the present atmosphere are discussed. Hattori, S., Danielache, S. O., Johnson, M. S., Schmidt, J. A., Kjaergaard, H. G., Toyoda, S., Ueno, Y., Yoshida, N. Ultraviolet absorption cross sections of carbonyl sulfide isotopologues OC32S, OC33S, OC34S and O13CS: isotopic fractionation in photolysis and atmospheric implications, Atmos. Chem. Phys., 11, 10293-10303, 2011. Schmidt, J. A., Johnson, M. S., Jung, Y., Danielache, S. O., Hattori, S., Yoshida, N., Predictions of the sulfur and carbon kinetic isotope effects in the OH + OCS reaction, Chem. Phys. Lett., 531, 64-69, 2012. Hattori, S., Schmidt J. A., Mahler D., Danielache, S. O., Johnson M. S., Yoshida N. Isotope Effect in the Carbonyl Sulfide Reaction with O(3P), J. Phys. Chem. A, 116, 3521-3526, 2012. Hattori, S., Toyoda, A., Toyoda, S., Ishino S., Ueno, Y., Yoshida, N.: Determination of the Sulfur Isotope Ratio in Carbonyl Sulfide using Gas Chromatography/Isotope Ratio Mass Spectrometry on Fragment Ions 32S+, 33S+, and 34S+, Anal. Chem., 87, 477-484, 2015. Kato, H., Saito, M., Nagahata, Y., Katayama, Y.: Degradation of ambient carbonyl sulfide by Mycobacterium spp. in soil. Microbiol., 154(1), 249-255, 2008.

Effect of chain extension on rheology and tensile properties of PHB and PHB-PLA blends

Science.gov (United States)

Bousfield, Glenn

Poly(3-hydroxybutyrate), referred to as PHB, is a bacterially-synthesized and biodegradable polymer which is being considered as a substitute for non-biodegradable bulk polymers like polypropylene. PHB is naturally extremely isotactic and naturally has a very high degree of crystallinity, resulting in a stiff but brittle material. The stability of PHB crystals also means that the melting point of the polymer is approximately 170°C, high with respect to similar polymers. For instance, the melting point of poly(4-hydroxybutyrate) is only 53°C (Saito, Nakamura, Hiramitsu, & Doi, 1996). Above 170°C, PHB is subject to a thermomechanical degradation mechanism, meaning that the polymer cannot be melted without degrading. One possible solution to the problem of degradation is to add a chain extender to the molten polymer to increase average molecular weight to counteract the molecular weight lost to degradation. In this work, a variety of chain extenders (JoncrylRTM ADR 4368-C, pyromellitic dianhydride, hexamethylene diisocyanate, polycarbodiimide) were compounded with a random copolymer of 98 mol% 3-hydroxybutyrate and 2 mol% 3-hydroxyvalerate (referred to as PHB) in concentrations ranging from 0.25% to 4%, to determine which chain extender functionality worked best with PHB. Molecular weight change was inferred from torque monitored during compounding, and from complex viscosity determined from parallel-plate rheology. None of the chain extenders changed the rate of degradation of PHB, although Joncryl increased the complex viscosity of the polymer. PHB was also blended with Poly(L-lactic acid), referred to as PLLA in PHB/PLLA ratios of 100/0, 75/25, 50/50, 25/75 and 0/100, to determine the effect of blending on the thermal stability of PHB. Again, thermal stability was determined by monitoring torque during compounding and by measuring complex viscosity through parallel-plate rheology. Blends in which PHB was the more abundant phase, as well as the 50% PHB/50% PLA

Study design and patient recruitment for the Japan Polyp Study

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Sano Y

2014-05-01

Full Text Available Yasushi Sano,1,2 Takahiro Fujii,3,4 Takahisa Matsuda,3 Yasushi Oda,5,6 Shin'ei Kudo,7 Masahiro Igarashi,8 Hiroyasu Iishi,9 Kazuhiro Kaneko,1,10 Kinichi Hotta,3,11,12 Nozomu Kobayashi,3,13 Yuichiro Yamaguchi,12 Kiyonori Kobayashi,8 Hideki Ishikawa,14 Yoshitaka Murakami,15 Tadakazu Shimoda,16 Takahiro Fujimori,17 Yoichi Ajioka,18 Hirokazu Taniguchi,16 Hiroaki Ikematsu,1,3 Kazuo Konishi,10 Yutaka Saito,3 Shigeaki Yoshida1,19 1Department of Gastroenterology, Endoscopy Division, National Cancer Center Hospital East, Kashiwa, 2Gastrointestinal Center and Institute of Minimally Invasive Endoscopic Care (iMEC, Sano Hospital, Kobe, 3Endoscopy Division, National Cancer Center Hospital, Tokyo, 4Takahiro Fujii Clinic, Tokyo, 5Hattori GI Endoscopy and Gastroenterology Clinic, Kumamoto, 6Oda GI Endoscopy and Gastroenterology Clinic, Kumamoto, 7Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, 8Department of Gastroenterology, Kitasato University East Hospital, Sagamihara, 9Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, 10Division of Gastroenterology, Department of Medicine, Showa University School of Medicine, Tokyo, 11Department of Gastroenterology, Saku Central Hospital, Saku, 12Division of Endoscopy, Shizuoka Cancer Center, Mishima, 13Department of Diagnostic Imaging, Tochigi Cancer Center, Utsunomiya, 14Department of Molecular-Targeting Cancer Prevention, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, 15Department of Medical Statistics, Shiga University of Medical Science, Otsu, 16Pathology and Clinical Laboratory Division, National Cancer Center Hospital, Tokyo, 17Department of Surgical and Molecular Pathology, Dokkyo Medical University School of Medicine, Mibu, 18Division of Molecular and Diagnostic Pathology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, 19Aomori Prefectural Hospital, Aomori

Azelnidipine plus olmesartan versus amlodipine plus olmesartan on arterial stiffness and cardiac function in hypertensive patients: a randomized trial

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Takami T

2013-04-01

Full Text Available CorrigendumTakami T, Saito Y. Drug Design, Development and Therapy. 2013;7:175–183. On page 177, line 26, heading "Measurement of LVMI and LF diastolic function" should have been "Measurement of LVMI and LV diastolic function". Line 32, "Devereux et al18" should read "Devereux et al19". Line 40, "(E/e’ ratio were measured as previously described.19" should read "(E/e’ ratio were measured as previously described.20". On page 181, line 15, "baPWV with LVMI.20" should read "baPWV with LVMI.21". Line 23, "baPWV and LVMI, E/A ratio.20" should read "baPWV and LVMI, E/A ratio.21,22". Line 28 "diastolic dysfunction.21" should read "diastolic dysfunction.23". Line 38 "is high.22" should read "is high.24". Line 39, "in clinical treatment.23" should read "in clinical treatment.25". Line 57, "A recent cohort study24" should read "A recent cohort study21".On page 182, line 1, "diastolic heart failure.25" should read "diastolic heart failure.26". Line 3, "untreated hypertensive patients.26" should read "untreated hypertensive patients.27". Line 6, "linear regression analysis.27" should read "linear regression analysis.21".On page 183, the references 18 to 27 should be updated as shown below:18. Takami T. Evaluation of arterial stiffness in morning hypertension under high-dose valsartan compared to valsartan plus low-dose diuretic. Hypertens Res. 2009;32:1086–1090.19. Devereux RB, Palmieri V, Sharpe N, et al. Effects of once-daily angiotensin-converting enzyme inhibition and calcium channel blockade-based antihypertensive treatment regimens on left ventricular hypertrophy and diastolic filling in hypertension: the prospective randomized enalapril study evaluating regression of ventricular enlargement (PRESERVE trial. Circulation. 2001;104:1248–1254.20. Ito H, Ishii K, Kihara H, et al. Adding thiazide to a renin-angiotensin blocker improves left ventricular relaxation and improves heart failure in patients with hypertension. Hypertens Res. 2012;35:93�

Cues for Cure; From within

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Editorial

2016-05-01

transplantation of exogenous stem cells, adult cells or precursors, though forms the main stream approach in regenerative medicine, in vivo stimulation of tissue resident stem cells has been postulated as a promising regenerative approach [5], probably owing to its safety compared to transplantation of exogenous cells, especially pluripotent stem cells. Further, even if exogenous cells are administered in cell-based therapies, it is the tissue resident cells with regenerative capability which actually contribute to the regeneration. Hence, unless the local niche/environment and other factors contributing to the maintenance of tissue resident stem cells or progenitor cells are studied and steps to recapitulate their contribution in moulding the function of exogenous stem cells to contribute to regeneration are performed in vitro, translational approaches in regeneration may not realize their expected outcome. The studies by Takeuchi et al and Jones and Connor in the current issue fall in line with this ideology and more such studies need to be encouraged for developing better therapies for the future. References: Barker N, Bartfeld S, Clevers H. Tissue-resident adult stem cell populations of rapidly self-renewing organs. Cell Stem Cell. 2010; 7(6:656-70. Miki K, Uenaka H, Saito A, Miyagawa S, Sakaguchi T, Higuchi T, Shimizu T, Okano T, Yamanaka S, Sawa Y. Bioengineered myocardium derived from induced pluripotent stem cells improves cardiac function and attenuates cardiac remodeling following chronic myocardial infarction in rats. Stem Cells Transl Med. 2012; 1(5:430-7. Takeuchi T, Tonooka A, Okuno Y, Hattori-Kato M, Mikami K. Oct4B, CD90, and CD73 are upregulated in bladder tissue following electro-resection of the bladder. J Stem Cells Regen Med 2016; 12(1 :10-15. Jones KS, Connor BJ. The Effect of Pro-Neurogenic Gene Expression on Adult Subventricular Zone Precursor Cell Recruitment and Fate Determination After Excitotoxic Brain Injury. J Stem Cells Regen Med 2016; 12(1 :25

I. T. - R. O. C. K. S. Comet Nuclei Sample Return Mission

Science.gov (United States)

Dalcher, N.

2009-04-01

samples will be performed by touch and go manoeuvres and a penetrator device [10]. Solar arrays are used as energy source and additional cooling is required to keep the samples at low temperatures (Lisse C., Schultz P., Meech K. J., Delamere W. A. Icarus 187,4-15 (2007). [4] Simon S.B., Joswiak D.J., Ishii H.A., Bradley J.P., Chi M., Grossman L., Aléon J., Brownlee D.E., Fallon S., Hutcheon I.D., Matrajt G., Mckeegan K.D.: Refractory Inclusion Returned by Stardust from Comet P81/Wild 2. Meteoritics and Planetary Science (2007). [5] George D. Cody, Harald Ade, Conel M. O'D. Alexander, Tohru Araki, Anna Butterworth, Holger Fleckenstein, George Flynn, Mary K. Gilles, Chris Jacobsen, A.L. D. Kilcoyne, Keiko Messenger, Scott A. Sandford, Tolek Tyliszczak, Andrew J.Westphal4, Susan Wirick, and Hikaru Yabuta. Quantitative Organic and Light Element analysis of Comet 81P/Wild 2 particles using C-, N-, and O- µ-XANES, Meteoretics and Planetary Science: In Press. [6] Stern, S. et al. Alice: The Rosetta Ultraviolet Imaging Spectrograph. Space Science Reviews 128, 507-527 (2007). [7] Balsiger, H. et al. Rosina-Rosetta Orbiter Spectrometer for Ion and Neutral Analysis. Space Science Reviews 128, 745-801 (2007). [8] Colangeli, L. et al. The Grain Impact Analyser and Dust Accumulator (GIADA) Experiment for the Rosetta Mission: Design, Performances and First Results. Space Science Reviews 128, 803-821 (2007). [9] Yoshimitsu, T., Kubota, T., Nakatani, I., Adachi, T. & Saito, H. Micro-hopping robot for asteroid exploration. Acta Astronautica 52, 441-446 (2003). [10] Lorenz, R. et al. Demonstration of comet sample collection by penetrator. ESA SP-542, 387-393 (2003). [11] Küppers et al. Triple F—a comet nucleus sample return mission. Experimental Astronomy, Online First (2008).

Specific features of the recent accumulation of 137Cs in tree roots of forest ecosystems within the zone of radioactive contamination

Science.gov (United States)

Shcheglov, Alexey; Tsvetnova, Ol'ga; Klyashtorin, Alexey; Popova, Evgenia

2015-04-01

Despite numerous studies of the accumulation of technogenic radionuclides in the root systems, no clear regularities of this process have been established. The tendencies found in the works of Russian and foreign researchers are rather discrepant. Some authors argue that the accumulation of radionuclides in the roots is more pronounced than that in the aboveground parts of the plants (Skovorodnikova, 2005; Romantseva, 2012; Sennerby et al., 1994; Mamikhin, 2002; Fircks et al., 2002}. Other works attest to a higher accumulation of radionuclides in the aboveground pars (Juznic et al., 1990; Chibowski, 2000; Zhianski et al., 2005), which is also typical of the stable isotopes of these elements, including 133Cs (Dong Jin Kang, YongJin Seo, Tsukasa Saito et al,2012). It is also stated that the accumulation of radionuclides in the aboveground and underground parts of plants may differ in dependence on the soil-ecological conditions and other factors (Kozhakhanov et al., 2011; Grabovskyi et al., 2013). The aim of our study was to evaluate the accumulation of 137Cs in the root systems of arboreal plants in forest ecosystems within the near zone of the Chernobyl fallout on the plots with similar soil and phytocenotic features. Pine and birch stands were studied within the 30-km-wide exclusion zone of the Chernobyl Nuclear Power Station in Ukraine in 1992-1993, when the density of the radioactive contamination of the upper (0-20 cm) layer with 137Cs reached 2153.8 kBq/m2), and in Bryansk oblast of Russia in 2013-2014, when the density of contamination varied from 1458.4 kBq/m2 (pine stand) to 2578.3 kBq/m2 (birch stand). The tree layer in these ecosystems was dominated by Pinus sylvestris (L.) and Betula pendula (Roth.), respectively. Quercus robur (L.), Picea abies (L.), and Sorbus aucuparia (L.) were also present. The specific activity of 137Cs was measured in the samples from the aboveground parts of model trees and their roots differentiated by size (0-3, 3-10, 10

Selected Abstracts of the 6th International Congress of UENPS; Valencia (Spain; November 23rd-25th 2016; Session “Miscellanea”

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--- Various Authors

2016-11-01

Full Text Available Selected Abstracts of the 6th International Congress of UENPS; Valencia (Spain; November 23rd-25th 2016; Session “Miscellanea”ABS 1. CALVARIAL AGENESIS AND APLASIA CUTIS CONGENITA: A CASE REPORT • F.P. Bunjamin, R.D. RoeslaniABS 2. NEUROCUTANEOUS MELANOSIS IN A NEWBORN • R. Tameliene, A. Vinskaite, J. Buinauskiene, R. DzikieneABS 3. TLR2/TLR6 HETERODIMER-MEDIATED INNATE IMMUNE RESPONSE IN CORD BLOOD IMMUNE CELLS • Y. Cho, D. Tokuhara, K. Nohmi, M. Saito, D. Tachibana, M. Koyama, H. ShintakuABS 4. PRADER-WILLI SYNDROME IN OUR HOSPITAL. ARE WE DIAGNOSING AND TREATING EARLY? • B. Rodriguez Azor, R. Roldán López, S. Ariza Aranda, D. López Martín, T. Fernandez Ferrandez, V. Schmitz, E. Salguero García, T. Sánchez TamayoABS 5. RISK FACTORS ASSOCIATED WITH PRENATAL EXPOSURE TO “SHABU” • J. Candel Pau, J. García García, C. Manzano Varo, L. Román Eyo, S. Calpe Fraile, MA. López-VílchezABS 6. VITAMIN D STATUS IN PREGNANT WOMEN AND NEWBORNS IN LA RIOJA AREA IN SPAIN • M. Ruiz, B. Riaño, MY. Ruiz, MP. Samper, P. VenturaABS 7. NEONATAL RESUSCITATION TRAINING COURSES. TRAINEES’ PERCEPTION • S. Zeballos Sarrato, G. Zeballos, C. Ramos, N. Oikonomopoulou, N. Navarro, M. Sánchez LunaABS 8. METABOLOMIC PROFILE IN NEWBORNS MIRRORS THAT OF THEIR MOTHERS IN PREGNANCY • S. Negro, M. Longini, ML. Tataranno, F. Proietti, M. Tassini, A. Vivi, F. Bazzini, E. Belvisi, F. Vanacore, M. Calderisi, G. Buonocore, S. PerroneABS 9. INTRAUTERINE MECONIUM PERITONITIS DUE TO SIGMOID PERFORATION OF UNKNOWN ETIOLOGY IN A 29 WEEKER: MANAGEMENT AND OUTCOME. A CASE PRESENTATION • M. Simon, M. Rusneac, R. Marian, Z.S. Gall, L.M. Suciu, M.C. CucereaABS 10. THE RESULTS OF NEWBORN HEARING SCREENING BY MEANS OF TRANSIENT OTOACOUSTIC EMISSIONS – HAS ANYTHING CHANGED OVER 10 YEARS? • K. Wroblewska-Seniuk, G. Greczka, P. Dabrowski, J. MazelaABS 11. NEONATAL GASTRIC PERFORATION: A REPORT OF ONE CASE IN OUR NICU • N. Lecumberri García, I

Generation of high reactive fluids by rapid clinopyroxene-seawater interaction: An experimental study at 425 °C, 40 and 100 MPa

Science.gov (United States)

Beermann, Oliver; Garbe-Schönberg, Dieter; Schächinger, Steffen; Arzi, Lisa; Holzheid, Astrid

2014-05-01

experiments significant amounts (~10-20 rel. %) of secondary mineral phases, i.e. talc, the serpentine-group minerals lizardite, antigorite, and chrysotile, and minor abundances of pyrrhotite and pentlandite were formed primarily on Cpx even after short run durations of 3 hours. Our results show that intense leaching of Ca, REEs, transition and trace metals only occurred with Cpx and only in the seawater experiments. Leaching was caused by rapid precipitation of the intitial seawater Mg (1400 ppm) on Cpx, which generated HCl(aq) with pH (25 °C) leaching. Because element exchange reactions between seawater and the other widespread abundant mineral olivine in the oceanic lithosphere are very sluggish at elevated pressure and temperature conditions [10], we conclude that in particular seawater interactions with un-leached pyroxenes creates high element fluxes during early-stage, high temperature MOR hydrothermalism, as it is evident from MAR 5° S fluids. This kind of hydrothermalism is expected to be not uncommon in particular at the slow-spreading MAR [9], and the high element fluxes here, most probably caused by seawater-pyroxene interactions, should be taken into account when modelling global chemical fluxes of MOR hydrothermalism. References: [1] German C. R., Thurnherr A. M., Knoery J., Charlou J.-L., Jean-Babtiste P., and Edmonds H. N. (2010) Deep Sea Res. 157, 518-527. [2] Schmidt K., Garbe-Schönberg D., Bau M., and Koschinsky A. (2010) Geochim. Cosmochim. Acta 74, 4058-4077. [3] Saito M. A., Noble A. E., Tagliabue A., Goepfert T. G., Lamborg C. H., and Jenkins W. J. (2013) Nat. Geosci. 5, 775-779. [4] German C. R., Bennett S. A., Connelly D. P., Evans A. J., Murton B. J., Parson L. M., Prien R. D., Ramirez-Llodra E., Jakuba M., Shank T. M., Yoerger D. R., Baker E. T., Walker S. L., and Nakamura K. (2008) Earth. Planet. Sci. Lett. 273, 332-344. [5] Haase K. M., Petersen S., Koschinsky A., and M64/1, M68/1 Scient. Parties (2007) Geochem. Geophys. Geosyst. 8, Q11002, doi

EDITORIAL: Focus on Carbon Nanotubes

Science.gov (United States)

2003-09-01

planes to stable loops caused by annealing M Endo, B J Lee, Y A Kim, Y J Kim, H Muramatsu, T Yanagisawa, T Hayashi, M Terrones and M S Dresselhaus Energetics and electronic structure of C70-peapods and one-dimensional chains of C70 Susumu Okada, Minoru Otani and Atsushi Oshiyama Theoretical characterization of several models of nanoporous carbon F Valencia, A H Romero, E Hernández, M Terrones and H Terrones First-principles molecular dynamics study of the stretching frequencies of hydrogen molecules in carbon nanotubes Gabriel Canto, Pablo Ordejón, Cheng Hansong, Alan C Cooper and Guido P Pez The geometry and the radial breathing mode of carbon nanotubes: beyond the ideal behaviour Jeno Kürti, Viktor Zólyomi, Miklos Kertesz and Sun Guangyu Curved nanostructured materials Humberto Terrones and Mauricio Terrones A one-dimensional Ising model for C70 molecular ordering in C70-peapods Yutaka Maniwa, Hiromichi Kataura, Kazuyuki Matsuda and Yutaka Okabe Nanoengineering of carbon nanotubes for nanotools Yoshikazu Nakayama and Seiji Akita Narrow diameter double-wall carbon nanotubes: synthesis, electron microscopy and inelastic light scattering R R Bacsa, E Flahaut, Ch Laurent, A Peigney, S Aloni, P Puech and W S Bacsa Sensitivity of single multiwalled carbon nanotubes to the environment M Krüger, I Widmer, T Nussbaumer, M Buitelaar and C Schönenberger Characterizing carbon nanotube samples with resonance Raman scattering A Jorio, M A Pimenta, A G Souza Filho, R Saito, G Dresselhaus and M S Dresselhaus FTIR-luminescence mapping of dispersed single-walled carbon nanotubes Sergei Lebedkin, Katharina Arnold, Frank Hennrich, Ralph Krupke, Burkhard Renker and Manfred M Kappes Structural properties of Haeckelite nanotubes Ph Lambin and L P Biró Structural changes in single-walled carbon nanotubes under non-hydrostatic pressures: x-ray and Raman studies Sukanta Karmakar, Surinder M Sharma, P V Teredesai, D V S Muthu, A Govindaraj, S K Sikka and A K Sood Novel properties of 0

Selected Abstracts of the 6th International Congress of UENPS; Valencia (Spain; November 23rd-25th 2016; Session “Infections and inflammation”

Directory of Open Access Journals (Sweden)

--- Various Authors

2016-11-01

Full Text Available Selected Abstracts of the 6th International Congress of UENPS; Valencia (Spain; November 23rd-25th 2016; Session “Infections and inflammation”ABS 1. ARE ANTIBIOTICS A RISK FACTOR FOR THE DEVELOPMENT OF NECROTIZING ENTEROCOLITIS? • A. Raba, A. O’Sullivan, J. MiletinABS 2. CLINICAL CHARACTERISTICS AND OUTCOME OF NEONATAL URINARY TRACT INFECTIONS • A. Hadzimuratovic, E. Hadzimuratovic, A. Dzananovic, I. Pasic SeficABS 3. FREQUENCY OF LATE-ONSET INFECTIONS DURING PRIMARY HOSPITALIZATION: DIFFERENCES BETWEEN SMALL-FOR-GESTATIONAL-AGE AND APPROPRIATE-FOR-GESTATIONAL-AGE PRETERM INFANTS • A. MaticABS 4. DIABETIC PREGNANCY ACTIVATES INNATE IMMUNE RESPONSE THROUGH TLR5 OR TLR1/2 ON CORD BLOOD-DERIVED MONOCYTES • D. Tokuhara, S. Yanai, D. Tachibana, M. Saito, Y. Cho, M. Koyama, H. ShintakuABS 5. CONGENITAL CYTOMEGALOVIRUS INFECTION: A CLINICAL STUDY • S. Stefanovic, V. Stefanovic, V. StefanovicABS 6. DIAGNOSTIC BIOMARKERS IN EARLY NEONATAL SEPSIS: TLR-2 AND TLR-4 VERSUS CONVENTIONAL MARKERS • G. Zaharie, L. Blaga, M. Hasmasanu, S. Bolboaca, M. MatyasABS 7. URINARY KIDNEY INJURY MARKERS IN NEONATES WITH URINARY TRACT INFECTION AND PNEUMONIA • A. Tarko, A. Suchojad, A. Brzozowska, M. Michalec, I. Maruniak-ChudekABS 8. EARLY DETECTION OF NEONATAL INFECTION AT BIRTH IN PREMATURE INFANTS BY CLINICAL AND LABORATORY MARKERS • A. Masseva, N. Jekova, E. Shopova, B. MarinovABS 9. PERSISTENT METABOLIC ACIDOSIS AND METHEMOGLOBINEMIA IN COW’S MILK PROTEIN-INDUCED ENTEROCOLITIS • M. Miñambres Rodríguez, C. Alonso Vicente, M. Pino, A. Pino Vázquez, J.M. Marugán de Miguelsanz, I. Sanz FernándezABS 10. INTERLEUKIN 17A IN BRONCHOALVEOLAR LAVAGE FLUID: AN EARLY MARKER OF VENTILATOR-ASSOCIATED PNEUMONIA (VAP IN PRETERM INFANTS • M. Cernada, J. Escobar, J. Kuligowski, A. Núñez, E. Cubells, A. Parra, M. VentoABS 11. VERY LOW WEIGHT PRETERM TWINS DIAGNOSED WITH LATE-ONSET SEPSIS SHOW CHANGES IN GUT MICROBIOTA PROFILES AND MUCOSAL

EDITORIAL: Invited papers from ISAMMA 2010 (Sendai, Japan, 12-16 July 2010) Invited papers from ISAMMA 2010 (Sendai, Japan, 12-16 July 2010)

Science.gov (United States)

Takahashi, M.; Saito, H.

2011-02-01

overseas. The programme involved 4 plenary talks, 37 invited talks, 85 contributed talks and 352 posters. All submitted papers were reviewed in order to meet the standards of Journal of Physics D: Applied Physics and Journal of Physics: Conference Series. We are grateful to all participants for their valuable contributions and active discussions. We gratefully acknowledge the financial support of 17 Japanese companies and 7 Japanese foundations. Invited papers from ISAMMA 2010 Contents Current status and recent topics of rare-earth permanent magnets S Sugimoto Alloying effect on the magnetic properties of RFeB-type bulk magnets H W Chang, C C Hsieh, J Y Gan, Y T Cheng, M F Shih and W C Chang Coercivity distributions in Nd-Fe-B sintered magnets produced by the grain boundary diffusion process H Nakamura, K Hirota, T Ohashi and T Minowa Recent progress in high Bs Fe-based nanocrystalline soft magnetic alloys M Ohta and Y Yoshizawa Electric-field effects on magnetic anisotropy in Pd/Fe/Pd(0 0 1) surface Shinya Haraguchi, Masahito Tsujikawa, Junpei Gotou and Tatsuki Oda Gate modulation of spin precession in a semiconductor channel Hyun Cheol Koo, Jae Hyun Kwon, Jonghwa Eom, Joonyeon Chang, Suk Hee Han and Mark Johnson Ferromagnetic resonance of epitaxial Fe nanodots grown on MgO measured using coplanar waveguides M Mizuguchi and K Takanashi Switching phase diagrams of current-induced magnetization switching in asymmetric MgO-based magnetic tunnel junctions Seung-Young Park, Jae-Ho Han, Se-Chung Oh, Jang-Eun Lee, Kyung-Tae Nam, Hyun-Woo Lee, Younghun Jo and Kyung-Jin Lee Temperature dependence of spin-dependent transport properties of Co2MnSi-based current-perpendicular-to-plane magnetoresistive devices Y Sakuraba, K Izumi, S Bosu, K Saito and K Takanashi Adsorbate-induced spin-polarization enhancement of Fe3O4(0 0 1) A Pratt, M Kurahashi, X Sun and Y Yamauchi Antiferromagnetic coupling between spinel ferrite and α-Fe layers in Fe3-δO4/MgO/Fe(0 0 1) epitaxial films Hideto

Multiparticle Production in Particle and Nuclear Collisions. I

Science.gov (United States)

Kanki, T.; Kinoshita, K.; Sumiyoshi, H.; Takagi, F.

should also cover good phenomenological models or pictures even though their theoretical foundations are not yet clear; it should be compact, comprehensive and self-contained. On the other hand, the reference list in this article will not be complete. As a very wide range of subject was covered, it was impossible to make a complete list by limitations of the authors' ability and of the time for editorial works. Instead, we selected the references only from the following points; references more comprehensible, more easily accessible by the reader, i.e., more in jounals than in books or conference papers. The reader would find detailed reference lists in each reference cited in this article. Even many original references are then omitted. We apologize to the authors of uncited papers. About how to read this review, the reader will find the detailed suggestions in A1 (Section 1 of Chapter A). In the past decade, many excellent research meetings on multiparticle production have been held at RIFP (Kyoto University), INS (Tokyo University) and KEK. These meetings were very effective for supporting active research works in this field in Japan. We deeply appreciate the promotions by these institutions. The authors are especially grateful to Professor Z. Maki for his continual encouragement and suggestion of this issue. Our thanks are also due to M. Biyajima, K. Hirose, T. Kagiyama, A. Minaka, O. Miyamura, H. Noda, K. Saito, N. Suzuki and T. Tashiro for useful discussions.

Multiparticle Production in Particle and Nuclear Collisions. II

Science.gov (United States)

Kanki, T.; Kinoshita, K.; Sumiyoshi, H.; Takagi, F.

should also cover good phenomenological models or pictures even though their theoretical foundations are not yet clear; it should be compact, comprehensive and self-contained. On the other hand, the reference list in this article will not be complete. As a very wide range of subject was covered, it was impossible to make a complete list by limitations of the authors' ability and of the time for editorial works. Instead, we selected the references only from the following points; references more comprehensible, more easily accessible by the reader, i.e., more in jounals than in books or conference papers. The reader would find detailed reference lists in each reference cited in this article. Even many original references are then omitted. We apologize to the authors of uncited papers. About how to read this review, the reader will find the detailed suggestions in A1 (Section 1 of Chapter A). In the past decade, many excellent research meetings on multiparticle production have been held at RIFP (Kyoto University), INS (Tokyo University) and KEK. These meetings were very effective for supporting active research works in this field in Japan. We deeply appreciate the promotions by these institutions. The authors are especially grateful to Professor Z. Maki for his continual encouragement and suggestion of this issue. Our thanks are also due to M. Biyajima, K. Hirose, T. Kagiyama, A. Minaka, O. Miyamura, H. Noda, K. Saito, N. Suzuki and T. Tashiro for useful discussions.

The relationship between the connecting peptide of recombined single chain insulin and its biological function

Institute of Scientific and Technical Information of China (English)

HUANG; Yiding; (

2001-01-01

［1］Straus, D. S., Growth-stimulatory of insulin in vitro and in vivo, Endocr. Rev., 1984, 5(2): 356-369.［2］Svenningsen, A. F., Kanje, M., Insulin and the insulin-like growth factors I and II are mitogenic to cultured rat sciatic nerve segments and stimulate [3H] thuymidine incorporation through their respective receptors, Glia, 1996, 18(1): 68-72.［3］Ogihara, S., Yamada, M., Saito, T. et al., Insulin potentiates mitogenic effect of epidermal growth factor on cultured guinea pig gastric mucous cells, Am. J. Physiol., 1996, 271(1 Pt 1): G104-121.［4］Steiner, D. F., Oyer, P. E., The biosynthesis of insulin and a probable precursor of insulin by a human islet cell adenoma, Proc. Nalt. Acad. Sci. USA, 1967, 57(2): 473-480.［5］King, G. L., Kahn, C. R., The growth-promoting effects of insulin, in Growth and Maturation Factors(ed. Guroff, G.), New York: John Wiley & Sons, 1984, 223-265.［6］Peavy, D. E., Brunner, M. R., Duckworth, W. C. et al., Receptor binding and biological potency of several split forms (conversion intermediates) of human proinsulin, Studies in cultured IM-9 lymphocytes and in vivo and in vitro in rats, J. Biol. Chem., 1985, 260: 13989-13994.［7］Derewenda, U., Derewenda, Z., Dodson, E. J. et al., X-ray analysis of the single chain B29-A1 peptide-linked insulin molecule. A completely inactive analogue, J. Mol. Biol., 1991, 220: 425-433.［8］Hua, Q. X., Shoelson, S. E., Kochoyan, M. et al., Receptor binding redefined by a structural switch in a mutant human insulin, Nature, 1991, 354: 238-241.［9］Hua, Q. X., Gozani, S. N., Chance, R. E. et al., Structure of a protein in a kinetic trap, Nat. Struc. Boil, 1995, 2: 129-138.［10］Kristensen, C., Andersen, A. S., Hach, M., A single-chain insulin-like growth factor I/insulin hybrid binds with high affinity to the insulin receptor, Biochem. J., 1995, 305: 981-986.［11］Humbel, R. E., Insulin-like growth factors I and II, Euro. J. Biochem., 1990, 190: 445-462.［12］Cooke, R. M

Condensed matter analogues of cosmology

Science.gov (United States)

Kibble, Tom; Srivastava, Ajit

2013-10-01

Ranjkesh, V Simonka, M Ambrozic, Z Bradac and S Kralj Morphogenesis of defects and tactoids during isotropic-nematic phase transition in self-assembled lyotropic chromonic liquid crystalsYoung-Ki Kim, Sergij V Shiyanovskii and Oleg D Lavrentovich Annihilation dynamics of stringlike topological defects in a nematic lyotropic liquid crystalR R Guimarães, R S Mendes, P R G Fernandes and H Mukai Duality between the dynamics of line-like brushes of point defects in 2D and strings in 3D in liquid crystalsSanatan Digal, Rajarshi Ray, P S Saumia and Ajit M Srivastava The multiuniverse transition in superfluid 3HeYury Bunkov Coherent topological defect dynamics and collective modes in superconductors and electronic crystalsD Mihailovic, T Mertelj, V V Kabanov and S Brazovskii Gaussianity revisited: exploring the Kibble-Zurek mechanism with superconducting ringsD J Weir, R Monaco, V P Koshelets, J Mygind and R J Rivers The Kibble-Zurek mechanism in a subcritical bifurcationM A Miranda, D Laroze and W González-Viñas Topological relics of symmetry breaking: winding numbers and scaling tilts from random vortex-antivortex pairsW H Zurek Causality and non-equilibrium second-order phase transitions in inhomogeneous systemsA del Campo, T W B Kibble and W H Zurek The role of causality in tunable Fermi gas condensatesJen-Tsung Hsiang, Chi-Yong Lin, Da-Shin Lee and Ray J Rivers Kibble-Zurek mechanism in a trapped ferromagnetic Bose-Einstein condensateHiroki Saito, Yuki Kawaguchi and Masahito Ueda D-brane solitons and boojums in field theory and Bose-Einstein condensatesKenichi Kasamatsu, Hiromitsu Takeuchi and Muneto Nitta Kibble-Zurek scaling and string-net coarsening in topologically ordered systemsAnushya Chandran, F J Burnell, Vedika Khemani and S L Sondhi Universal frozen spectra after time-dependent symmetry restoring phase transitionsFriedemann Queisser, Patrick Navez and Ralf Schützhold Microscopic theory of non-adiabatic response in real and imaginary timeC De Grandi, A

EDITORIAL: Nanotechnology in motion Nanotechnology in motion

Science.gov (United States)

Demming, Anna

2012-02-01

, Toshio Ando from the University of Kanazawa provides an overview of developments that have allowed atomic force microscopy to move from rates of the order of one frame a minute to over a thousand frames per second in constant height mode, as reported by Mervyn Miles and colleagues at Bristol University and University College London [8]. Among the pioneers in the field, Ando's group demonstrated the ability to record the Brownian motion of myosin V molecules on mica with image capture rates of 100 x 100 pixels in 80 ms over a decade ago [9]. The developments unleash the potential of atomic force microscopy to observe the dynamics of biological and materials systems. If seeing is believing, the ability to present real motion pictures of the nanoworld cannot fail to capture the public imagination and stimulate burgeoning new avenues of scientific endeavour. Nearly 350 years on from the publication Micrographia, images in microscopy have moved from the page to the movies. References [1] Binnig G, Quate C F, and Gerber Ch 1986 Phys. Rev. Lett. 56 930-3 [2] Ando T 2012 Nanotechnology 23 062001 [3] J G 1934 Nature 134 635-6 [4] Bharadwaj P, Anger P and Novotny L 2007 Nanotechnology 18 044017 [5] The Nobel Prize in Physics 1986 Nobelprize.org [6] Kim K K, Reina A, Shi Y, Park H, Li L-J, Lee Y H and Kong J 2010 Nanotechnology 21 285205 [7] Phillips D B, Grieve J A, Olof S N, Kocher S J, Bowman R, Padgett M J, Miles M J and Carberry D M 2011 Nanotechnology 22 285503 [8] Picco L M, Bozec L, Ulcinas A, Engledew D J, Antognozzi M, Horton M A and Miles M J 2007 Nanotechnology 18 044030 [9] Ando T, Kodera N, Takai E, Maruyama D, Saito K and Toda A 2001 Proc. Natl. Acad. Sci. 98 12468

EDITORIAL: Announcing the 2009 Measurement Science and Technology Outstanding Paper Awards Announcing the 2009 Measurement Science and Technology Outstanding Paper Awards

Science.gov (United States)

Foss, John; Dewhurst, Richard; Fujii, Kenichi; Regtien, Paul

2010-06-01

out at the European Solar Test Installation at Ispra in Italy. After describing the measurement methods, the authors discuss at length the calculations of measurement uncertainty. This leads to a rigorous discussion of relative uncertainties from measurement parameters. Uncertainties arise from a range of parameters that include small contributions from electrical, temperature and fill factor parameters. But the greatest arises from uncertainties both in the optical source and in the reference cell. As a consequence, the authors make a convincing case both for identifying the sources of uncertainty and for reducing overall uncertainties from +/-2.6% to below +/-2%. The conclusions are concise, and the paper is rounded off with a list of 34 references with several papers cited from 2005 onwards. This paper was rated as excellent by external referees, and has been downloaded several hundred times since its publication. It is one of 30 papers nominated this year in the Measurement Science category, and gained most votes from those short-listed. The discussion on measurement uncertainty sets a fine example to all researchers involved in experimental measurement science. 2009 Award Winners—Optical and Laser-based Techniques Measurement of tiny droplets using a newly developed optical fibre probe micro-fabricated by a femtosecond pulse laser T Saito, K Matsuda, Y Ozawa, S Oishi and S Aoshima Shizuoka University, 3-5-1 Johoku, Naka-ku Hamamatsu, Shizuoka 432-8561, Japan CRL, Hamamatsu Photonics K.K., 5000 Hirakuchi, Hamakita-ku Hamamatsu, Shizuoka 434-8601, Japan This Award goes to a paper [5] describing a fascinating and novel optical fibre probe applied to measurements in gas-liquid two-phase flows. Optical probes have already been widely applied to two-phase flows. These include the use of four-tip optical probes (F-TOP) for millimetre-size bubbles/droplets, and a single-tip optical fibre probe (S-TOP) for sub-millimetre size bubbles/droplets. This new paper describes

PREFACE: Complex dynamics of fluids in disordered and crowded environments Complex dynamics of fluids in disordered and crowded environments

Science.gov (United States)

Coslovich, Daniele; Kahl, Gerhard; Krakoviack, Vincent

2011-06-01

T Fischer and R L C Vink Lennard-Jones binary mixture in disordered matrices: exploring the mode coupling scenario at increasing confinement P Gallo and M Rovere Static and dynamic contributions to anomalous chain dynamics in polymer blends Marco Bernabei, Angel J Moreno and J Colmenero Anomalous transport of a tracer on percolating clusters Markus Spanner, Felix Höfling, Gerd E Schröder-Turk, Klaus Mecke and Thomas Franosch Long-wavelength anomalies in the asymptotic behavior of mode-coupling theory S K Schnyder, F Höfling, T Franosch and Th Voigtmann Dynamic arrest of colloids in porous environments: disentangling crowding and confinement Jan Kurzidim, Daniele Coslovich and Gerhard Kahl Slow dynamics, dynamic heterogeneities, and fragility of supercooled liquids confined in random media Kang Kim, Kunimasa Miyazaki and Shinji Saito

Biological soil crusts are the main contributor to winter soil respiration in a temperate desert ecosystem of China

Science.gov (United States)

He, M. Z.

2012-04-01

distribute with cover about 1% of the entire study area. Prior to revegetation, straw-checkerboards approximately 1×1 m2 in area were constructed using wheat or rice straw to stabilize the dune surface and allow time for the planted xerophytic shrubs to adapt to the new environment. In 1956, the following 2-year-old xerophytic shrub seedlings were planted within the checkerboard at a density of 16 individuals per 100 m2 and grown without irrigation: Artemisia ordosica Krasch, H. scoparium Fisch, Calligonum mongolicum Turc'z, Caragana microphylla Lam., Caragana korshinskii Kom, Salix gordejevii and Atraphaxis bracteata A.Los. The stabilized area was then expanded to parallel areas in 1964 and 1982 using the same method and species. As a result, the initial stages of change that have occurred at these sites were similar. After more than fifties years succession, the predominant plants are semi-shrubs, shrubs, forbs, and grasses at present and BSCs formed. The common BSCs in the region may be dominated by cyanobacteria, algae, lichens and mosses, or any combination of these organisms. Cyanobacteria species include Microcolous vaginatus Gom., Hydrocoleus violacens Gom., Lyngbya crytoraginatus Schk., Phormidium amblgum Gom., P. autumnale (Ag.) Gom., P. foveolarum (Mont.) Gom. and Phormidium luridum (Kutz) Gom. etc; algal species mainly include Anabaena azotica Ley, Euglena sp., Hantzschia amphioxys var capitata Grum, Oscillatoria obscura Gom., O. pseudogeminate G. Schm. And Scytonema javanicum (Kutz) Bornet Flash etc; lichen species include Collema tenax (Sw.) Ach., Endocarpon pusillum Hedw.; and moss species are dominated by Bryum argenteum Hedw., Didymodon constrictus (Mitt.) Saito., Tortula bidentata Bai Xue Liang and T. desertorum Broth.. Experimental Design and Rs measurements On October 2010, We selected the moss-dominated BSCs at four revegetation sites and natural vegetation sites, in which 3 replicated plots were selected randomly. In each plot, olyvinyl chloride (PVC

EDITORIAL: Colloidal dispersions in external fields Colloidal dispersions in external fields

Science.gov (United States)

Löwen, Hartmut

2012-11-01

, Chatterji A, Winkler R G, Gompper G 2012 J. Phys. Condens. Matter 24 464103 [7]Laurati M et al 2012 J. Phys. Condens. Matter 24 464104 [8]Harrer C J, Winter D, Horbach J, Fuchs M and Voigtmann T 2012 J. Phys. Condens. Matter 24 464105 [9]De Puit R J and Squires T M 2012 J. Phys. Condens. Matter 24 464106 [10]De Puit R J and Squires T M 2012 J. Phys. Condens. Matter 24 464107 [11]Contreras-Aburto C and Nägele G 2012 J. Phys. Condens. Matter 24 464108 [12]Palberg T, Köller T, Sieber B, Schweinfurth H, Reiber H and Nägele G 2012 J. Phys. Condens. Matter 24 464109 [13]Papadopoulos P, Deng X and Vollmer D 2012 J. Phys. Condens. Matter 24 464110 [14]Schmitz R and Dünweg B 2012 J. Phys. Condens. Matter 24 464111 [15]Zhou J and Schmid F 2012 J. Phys. Condens. Matter 24 464112 [16]Smallenburg F, Vutukuri H R, Imhof A, van Blaaderen A and Dijkstra M 2012 J. Phys. Condens. Matter 24 464113 [17]Vissers T, Wysocki A, Rex M, Löwen H, Royall C P, Imhof A and van Blaaderen A 2011 Soft Matter 7 2352 [18]Glanz T and Löwen H 2012 J. Phys. Condens. Matter 24 464114 [19]Kohl M, Ivlev A, Brand P, Morfill G E and Löwen H 2012 J. Phys. Condens. Matter 24 464115 [20]Hanes R D L and Egelhaaf S U 2012 J. Phys. Condens. Matter 24 464116 [21]Mazilu M, Rudhall A, Wright E M and Dholakia K 2012 J. Phys. Condens. Matter 24 464117 [22]Dillmann P, Maret G and Keim P 2012 J. Phys. Condens. Matter 24 464118 [23]Wilms D et al 2012 J. Phys. Condens. Matter 24 464119 [24]Kreuter C, Siems U, Henseler P, Nielaba P, Leiderer P and Erbe A 2012 J. Phys. Condens. Matter 24 464120 [25]Malijevsky A and Jackson G 2012 J. Phys. Condens. Matter 24 464121 [26]Statt A, Winkler A, Virnau P and Binder K 2012 J. Phys. Condens. Matter 24 464122 [27]Oğuz E C, Löwen H, Reinmüller A, Schöpe H J, Palberg T and Messina R 2012 J. Phys. Condens. Matter 24 464123 [28]Oettel M 2012 J. Phys. Condens. Matter 24 464124 [29]Zeng Y and van Klitzing R 2012 J. Phys. Condens. Matter 24 464125 [30]Bonilla-Capilla B, Ramirez-Saito A

EDITORIAL: From reciprocal space to real space in surface science From reciprocal space to real space in surface science

Science.gov (United States)

Bartels, Ludwig; Ernst, Karl-Heinz

2012-09-01

Triest.let's finish—aus basta Some move atoms around to hear how they sound.Karl-Heinz Rieder, Erice, 6 April 1998 From reciprocal space to real space in surface science contents From reciprocal space to real space in surface scienceLudwig Bartels and Karl-Heinz Ernst Karl-Heinz Reider: the quiet pioneerGiorgio Benedek Scattering of CO and N2 molecules by a graphite surfaceJunepyo Oh, Takahiro Kondo, Keitaro Arakawa, Yoshihiko Saito, Junji Nakamura, W W Hayes and J R Manson Helium, neon and argon diffraction from Ru(0001)M Minniti, C Díaz, J L Fernández Cuñado, A Politano, D Maccariello, F Martín, D Farías and R Miranda Enhanced charge transfer in a monolayer of the organic charge transfer complex TTF-TNAP on Au(111)T R Umbach, I Fernandez-Torrente, J N Ladenthin, J I Pascual and K J Franke Extended pattern recognition scheme for self-learning kinetic Monte Carlo simulationsSyed Islamuddin Shah, Giridhar Nandipati, Abdelkader Kara and Talat S Rahman Acetylene on Cu(111): imaging a molecular surface arrangement with a constantly rearranging tipYeming Zhu, Jonathan Wyrick, Kamelia D Cohen, Katie Marie Magnone, Connor Holzke, Daniel Salib, Quan Ma, Dezheng Sun and Ludwig Bartels Coulomb attraction during the carpet growth mode of NaClFriederike Matthaei, Sarah Heidorn, Konrad Boom, Cord Bertram, Ali Safiei, Jörg Henzl and Karina Morgenstern Molecular self-assembly on an insulating surface: interplay between substrate templating and intermolecular interactionsMarkus Kittelmann, Philipp Rahe and Angelika Kühnle Vertical manipulation of native adatoms on the InAs(111)A surfaceJ Yang, C Nacci, J Martínez-Blanco, K Kanisawa and S Fölsch Charge transfer between isomer domains on n+-doped Si(111)-2 × 1: energetic stabilizationR M Feenstra, G Bussetti, B Bonanni, A Violante, C Goletti, P Chiaradia, M G Betti and C Mariani Probing the properties of metal-oxide interfaces: silica films on Mo and Ru supportsLeonid Lichtenstein, Markus Heyde, Stefan Ulrich, Niklas Nilius

EDITORIAL: Opposites attract: nanomagnetism in theory and practice Opposites attract: nanomagnetism in theory and practice

Science.gov (United States)

Demming, Anna

2012-09-01

Applications of artificial intelligence for chemical inference. XVII. An approach to computer-assisted elucidation of molecular structure J. Am. Chem. Soc. 97 5755-62 [7] Saito S, Oshiyama A, Miyamoto Y, Hamada N and Sawada S 1992 Electronic structure of fullerenes and fullerides: artificial atoms and their solids Nanotechnology 3 167-72 [8] Shinohara H 2000 Endohedral metallofullerenes Rep. Prog. Phys. 63 843-92 [9] Heitmann D, Kern K, Demel T, Grambow P, Ploog K and Zhang Y H 1992 Spectroscopy of quantum dots and antidots Surf. Sci. 267 245-52 [10] Andergassen S, Meen V, Schoeller H, Splettstoesser J and Wegewijs M R 2010 Charge transport through single molecules, quantum dots and quantum wires Nanotechnology 21 272001 [11] Lim W H, Yang C H, Zwanenburg F A and Dzurak A S 2011 Spin filling of valley-orbit states in a silicon quantum dot Nanotechnology 22 335704

PREFACE: Symmetries and Integrability of Difference Equations

Science.gov (United States)

Doliwa, Adam; Korhonen, Risto; Lafortune, Stéphane

2007-10-01

M Sergeev on quantization of three-wave equations. Random matrix theory. This section contains a paper by A V Kitaev on the boundary conditions for scaled random matrix ensembles in the bulk of the spectrum. Symmetries and conservation laws. In this section we have five articles. H Gegen, X-B Hu, D Levi and S Tsujimoto consider a difference-analogue of Davey-Stewartson system giving its discrete Gram-type determinant solution and Lax pair. The paper by D Levi, M Petrera, and C Scimiterna is about the lattice Schwarzian KDV equation and its symmetries, while O G Rasin and P E Hydon study the conservation laws for integrable difference equations. S Saito and N Saitoh discuss recurrence equations associated with invariant varieties of periodic points, and P H van der Kamp presents closed-form expressions for integrals of MKDV and sine-Gordon maps. Ultra-discrete systems. This final category contains an article by C Ormerod on connection matrices for ultradiscrete linear problems. We would like to express our sincerest thanks to all contributors, and to everyone involved in compiling this special issue.

PREFACE: Dynamics of low-dimensional systems Dynamics of low-dimensional systems

Science.gov (United States)

Bernasconi, M.; Miret-Artés, S.; Toennies, J. P.

2012-03-01

Chulkov Surface phonons on Pb(111) I Yu Sklyadneva, R Heid, K-P Bohnen, P M Echenique and E V Chulkov Using evidence from nanocavities to assess the vibrational properties of external surfaces G F Cerofolini, F Corni, S Frabboni, G Ottaviani, E Romano, R Tonini and D Narducci Magnetic properties and relaxation dynamics of a frustrated Ni7 molecular nanomagnet E Garlatti, S Carretta, M Affronte, E C Sañudo, G Amoretti and P Santini A theoretical study of rotational and translational diffusion dynamics of molecules with a six-fold point symmetry adsorbed on a hexagonal lattice by neutron scattering I Calvo-Almazán, S Miret-Artés and P Fouquet Vibrational dynamics and surface structure of Bi(111) from helium atom scattering measurements M Mayrhofer-Reinhartshuber, A Tamtögl, P Kraus, K H Rieder and W E Ernst Double and triple ionization of silver clusters by electron impactAvik Halder, Anthony Liang, Chunrong Yin and Vitaly V Kresin Scattering of O2 from a graphite surface W W Hayes, Junepyo Oh, Takahiro Kondo, Keitaro Arakawa, Yoshihiko Saito, Junji Nakamura and J R Manson Zero-phonon lines of systems with different dimensions and unconventional vibronic interactions V Hizhnyakov A kinetic Monte Carlo approach to investigate antibiotic translocation through bacterial porins Matteo Ceccarelli, Attilio V Vargiu and Paolo Ruggerone Quantum Zeno and anti-Zeno effects in surface diffusion of interacting adsorbates H C Peñate-Rodrìguez, R Martìnez-Casado, G Rojas-Lorenzo, A S Sanz and S Miret-Artés Weakly bound finite systems: (4He)N-Rb2(3Σu), clustering structures from a quantum Monte Carlo approach D López-Durán, R Rodrìguez-Cantano, T González-Lezana, G Delgado-Barrio, P Villarreal, E Yurtsever and F A Gianturco Multiphonon atom-surface scattering from corrugated surfaces: derivation of the inelastic scattering spectrum for diffraction statesBranko Gumhalter Probing the non-pairwise interactions between CO molecules moving on a Cu(111) surfacePepijn R Kole, Holly

EDITORIAL: Focus on Dilute Magnetic Semiconductors FOCUS ON DILUTE MAGNETIC SEMICONDUCTORS

Science.gov (United States)

Chambers, Scott A.; Gallagher, Bryan

2008-05-01

Chisholm, J D Budai and D P Norton Role of charge carriers for ferromagnetism in cobalt-doped rutile TiO2 T Fukumura, H Toyosaki, K Ueno, M Nakano and M Kawasaki Ab-initio study of exchange constants and electronic structure in diluted magnetic group-IV semiconductors Silvia Picozzi and Marjana Ležaić Phase coherent transport in (Ga,Mn)As D Neumaier, K Wagner, U Wurstbauer, M Reinwald, W Wegscheider and D Weiss Hydrogen interstitials-mediated ferromagnetism in MnxGe1-x magnetic semiconductors Xin-Xin Yao, Shi-Shen Yan, Shu-Jun Hu, Xue-Ling Lin, Chong Han, Yan-Xue Chen, Guo-Lei Liu and Liang-Mo Mei Electronic structures of magnetic semiconductors FeCr2Se4 and Fe0.5Cu0.5Cr2Se4 B I Min, Seung Su Baik, H C Choi, S K Kwon and J-S Kang Investigation of pure and Co2+-doped ZnO quantum dot electronic structures using the density functional theory: choosing the right functional Ekaterina Badaeva, Yong Feng, Daniel R Gamelin and Xiaosong Li Magnetic properties of sol-gel-derived doped ZnO as a potential ferromagnetic semiconductor: a synchrotron-based study N R S Farley, K W Edmonds, A A Freeman, G van der Laan, C R Staddon, D H Gregory and B L Gallagher Local electronic structure of Cr in the II-VI diluted ferromagnetic semiconductor Zn1-xCrxTe M Kobayashi, Y Ishida, J I Hwang, G S Song, A Fujimori, C S Yang, L Lee, H-J Lin, D J Huang, C T Chen, Y Takeda, K Terai, S-I Fujimori, T Okane, Y Saitoh, H Yamagami, K Kobayashi, A Tanaka, H Saito and K Ando Lack of ferromagnetism in n-type cobalt-doped ZnO epitaxial thin films T C Kaspar, T Droubay, S M Heald, P Nachimuthu, C M Wang, V Shutthanandan, C A Johnson, D R Gamelin and S A Chambers XMCD studies on Co and Li doped ZnO magnetic semiconductors Thomas Tietze, Milan Gacic, Gisela Schütz, Gerhard Jakob, Sebastian Brück and Eberhard Goering Ferromagnetic semiconductors and the role of disorder B W Wessels An extensive comparison of anisotropies in MBE grown (Ga,Mn)As material C Gould, S Mark, K Pappert, R G Dengel, J Wenisch, R P

EDITORIAL: Focus on Cold and Ultracold Molecules FOCUS ON COLD AND ULTRACOLD MOLECULES

Science.gov (United States)

Carr, Lincoln D.; Ye, Jun

2009-05-01

öhlich, A Griesmaier, T Pfau, H Saito, Y Kawaguchi and M Ueda High-energy-resolution molecular beams for cold collision studies L P Parazzoli, N Fitch, D S Lobser and H J Lewandowski Collisional effects in the formation of cold guided beams of polar molecules M Motsch, C Sommer, M Zeppenfeld, L D van Buuren, P W H Pinkse and G Rempe Towards sympathetic cooling of large molecules: cold collisions between benzene and rare gas atoms P Barletta, J Tennyson and P F Barker Efficient formation of ground-state ultracold molecules via STIRAP from the continuum at a Feshbach resonance Elena Kuznetsova, Marko Gacesa, Philippe Pellegrini, Susanne F Yelin and Robin Côté Emergent timescales in entangled quantum dynamics of ultracold molecules in optical lattices M L Wall and L D Carr Rotational state resolved photodissociation spectroscopy of translationally and vibrationally cold MgH+ ions: toward rotational cooling of molecular ions K Højbjerre, A K Hansen, P S Skyt, P F Staanum and M Drewsen Collective transverse cavity cooling of a dense molecular beam Thomas Salzburger and Helmut Ritsch A Stark decelerator on a chip Samuel A Meek, Horst Conrad and Gerard Meijer Deceleration of molecules by dipole force potential: a numerical simulation Susumu Kuma and Takamasa Momose Ultracold molecules: vehicles to scalable quantum information processing Kathy-Anne Brickman Soderberg, Nathan Gemelke and Cheng Chin Magnetic field modification of ultracold molecule-molecule collisions T V Tscherbul, Yu V Suleimanov, V Aquilanti and R V Krems Spectroscopy of 39K85Rb triplet excited states using ultracold a 3Σ+ state molecules formed by photoassociation J T Kim, D Wang, E E Eyler, P L Gould and W C Stwalley Pumping vortex into a Bose-Einstein condensate of heteronuclear molecules Z F Xu, R Q Wang and L You Intense atomic and molecular beams via neon buffer-gas cooling David Patterson, Julia Rasmussen and John M Doyle Dynamical properties of dipolar Fermi gases T Sogo, L He, T Miyakawa, S Yi, H Lu