NCBI nr-aa BLAST: CBRC-DYAK-02-0025 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-DYAK-02-0025 ref|YP_001502923.1| protein-export membrane protein SecD [Shewanella pealean...a ATCC 700345] gb|ABV88388.1| protein-export membrane protein SecD [Shewanella pealeana ATCC 700345] YP_001502923.1 2.2 26% ...

Topotactic reduction and reoxidation of hexagonal RCu{sub 0.5}Ti{sub 0.5}O{sub 3} (R = Y, Eu-Lu) Phases

Energy Technology Data Exchange (ETDEWEB)

Jiang, Peng, E-mail: jiangp@onid.orst.edu [Department of Chemistry, Oregon State University, Corvallis, OR 97331-4003 (United States); Berthelot, Romain, E-mail: berthelot.rom@gmail.com [Department of Chemistry, Oregon State University, Corvallis, OR 97331-4003 (United States); Li, Jun, E-mail: jli100@yahoo.com [Department of Chemistry, Oregon State University, Corvallis, OR 97331-4003 (United States); Sleight, A.W., E-mail: arthur.sleight@oregonstate.edu [Department of Chemistry, Oregon State University, Corvallis, OR 97331-4003 (United States); Subramanian, M.A., E-mail: mas.subramanian@oregonstate.edu [Department of Chemistry, Oregon State University, Corvallis, OR 97331-4003 (United States)

2013-06-01

Highlights: ► Topotactic reduction of hexagonal RCu{sub 0.5}Ti{sub 0.5}O{sub 3} phases is performed. ► TGA and magnetism indicate a formula of RCu{sub 0.5}Ti{sub 0.5}O{sub 2.78} for the reduced phase. ► Topotactic reoxidation occurs on heating these phases to 400 °C in air. - Abstract: Hexagonal AMO{sub 2} and AMO{sub 3} phases have the same basic structure, and intermediate compositions for this structure have been prepared by topotactic oxidation of AMO{sub 2} phases such as RCuO{sub 2}, where R is a trivalent rare earth cation. We now find that such intermediate phases can also be prepared by topotactic reduction of hexagonal RCu{sub 0.5}Ti{sub 0.5}O{sub 3} (R = Y, Tb-Lu) phases. Our TGA and magnetic susceptibility studies indicate a formula of RCu{sub 0.5}Ti{sub 0.5}O{sub 2.78} for these reduced phases. Topotactic reoxidation occurs on heating these phases to 400 °C in air.

NCBI nr-aa BLAST: CBRC-PTRO-01-0025 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-PTRO-01-0025 gb|AAG28020.1| hypocretin receptor-1 [Homo sapiens] gb|AAL47214.1| hypocretin... receptor 1; orexin receptor 1 [Homo sapiens] gb|AAL50221.1| hypocretin receptor 1 [Homo sapiens...] gb|AAH74796.1| Hypocretin (orexin) receptor 1 [Homo sapiens] gb|EAX07602.1| hypocretin (orexin) receptor 1, isoform CRA_c [Homo sapiens] AAG28020.1 0.0 91% ...

NCBI nr-aa BLAST: CBRC-HSAP-20-0025 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-HSAP-20-0025 ref|NP_005277.2| neuropeptides B/W receptor 2 [Homo sapiens] emb|CAC17004.1| neuropeptides... B/W receptor 2 [Homo sapiens] gb|AAH67481.1| Neuropeptides B/W receptor 2 [Homo sa...piens] gb|AAH67482.1| Neuropeptides B/W receptor 2 [Homo sapiens] gb|EAW75161.1| neuropeptides B/W receptor 2 [Homo sapiens] NP_005277.2 0.0 100% ...

Luminescence and magnetic properties of novel nanoparticle-sheathed 3D Micro-Architectures of Fe0.5R0.5(MoO4)1.5:Ln3+ (R = Gd3+, La3+), (Ln = Eu, Tb, Dy) for bifunctional application

Science.gov (United States)

Krishnan, Rajagopalan; Thirumalai, Jagannathan; Kathiravan, Arunkumar

2015-01-01

For the first time, we report the successful synthesis of novel nanoparticle-sheathed bipyramid-like and almond-like Fe0.5R0.5(MoO4)1.5:Ln3+ (R = Gd3+, La3+), (Ln = Eu, Tb, Dy) 3D hierarchical microstructures through a simple disodium ethylenediaminetetraacetic acid (Na2EDTA) facilitated hydrothermal method. Interestingly, time-dependent experiments confirm that the assembly-disassembly process is responsible for the formation of self-aggregated 3D architectures via Ostwald ripening phenomena. The resultant products are characterized by x-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), high resolution transmission electron microscopy (HRTEM), photoluminescence (PL), and magnetic measurements. The growth and formation mechanisms of the self-assembled 3D micro structures are discussed in detail. To confirm the presence of all the elements in the microstructure, the energy loss induced by the K, L shell electron ionization is observed in order to map the Fe, Gd, Mo, O, and Eu components. The photo luminescence properties of Fe0.5R0.5(MoO4)1.5 doped with Eu3+, Tb3+, Dy3+ are investigated. The room temperature and low temperature magnetic properties suggest that the interaction between the local-fields introduced by the magnetic Fe3+ ions and the R3+ (La, Gd) ions in the dodecahedral sites determine the magnetism in Fe0.5R0.5(MoO4)1.5:Eu3+. This work provides a new approach to synthesizing the novel Fe0.5R0.5(MoO4)1.5:Ln3+ for bi-functional magnetic and luminescence applications.

Secondary structures of rRNAs from all three domains of life.

Directory of Open Access Journals (Sweden)

Anton S Petrov

Full Text Available Accurate secondary structures are important for understanding ribosomes, which are extremely large and highly complex. Using 3D structures of ribosomes as input, we have revised and corrected traditional secondary (2° structures of rRNAs. We identify helices by specific geometric and molecular interaction criteria, not by co-variation. The structural approach allows us to incorporate non-canonical base pairs on parity with Watson-Crick base pairs. The resulting rRNA 2° structures are up-to-date and consistent with three-dimensional structures, and are information-rich. These 2° structures are relatively simple to understand and are amenable to reproduction and modification by end-users. The 2° structures made available here broadly sample the phylogenetic tree and are mapped with a variety of data related to molecular interactions and geometry, phylogeny and evolution. We have generated 2° structures for both large subunit (LSU 23S/28S and small subunit (SSU 16S/18S rRNAs of Escherichia coli, Thermus thermophilus, Haloarcula marismortui (LSU rRNA only, Saccharomyces cerevisiae, Drosophila melanogaster, and Homo sapiens. We provide high-resolution editable versions of the 2° structures in several file formats. For the SSU rRNA, the 2° structures use an intuitive representation of the central pseudoknot where base triples are presented as pairs of base pairs. Both LSU and SSU secondary maps are available (http://apollo.chemistry.gatech.edu/RibosomeGallery. Mapping of data onto 2° structures was performed on the RiboVision server (http://apollo.chemistry.gatech.edu/RiboVision.

Evolution of primary and secondary structures in 5S and 5.8S rRNA

International Nuclear Information System (INIS)

Curtiss, W.C.

1986-01-01

The secondary structure of Bombyx mori 5S rRNA was studied using the sing-strand specific S1 nuclease and the base pair specific cobra venom ribonuclease. The RNA was end-labeled with [ 32 P] at either the 5' or 3' end and sequenced using enzymatic digestion techniques. These enzymatic data coupled with thermodynamic structure prediction were used to generate a secondary structure for 5S rRNA. A computer algorithm has been implemented to aid in the comparison of a large set of homologous RNAs. Eukaryotic 5S rRNA sequences from thirty four diverse species were compared by (1) alignment or the sequences, (2) the positions of substitutions were located with respect to the aligned sequence and secondary structure, and (3) the R-Y model of base stacking was used to study stacking pattern relationships in the structure. Eukaryotic 5S rRNA was found to have significant sequence variation throughout much of the molecule while maintaining a relatively constant secondary structure. A detailed analysis of the sequence and structure variability in each region of the molecule is presented

NCBI nr-aa BLAST: CBRC-OSAT-12-0025 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-OSAT-12-0025 ref|NP_186955.1| CSLD3 (CELLULOSE SYNTHASE-LIKE 3); cellulose syn...thase/ transferase, transferring glycosyl groups [Arabidopsis thaliana] gb|AAF26119.1|AC012328_22 putative cellulose... synthase catalytic subunit [Arabidopsis thaliana] gb|AAG60543.1|AF232907_1 cellulose synthase-like ...CSLD3 [Arabidopsis thaliana] gb|AAK25890.1|AF360180_1 putative cellulose synthase... catalytic subunit [Arabidopsis thaliana] gb|AAK64073.1| putative cellulose synthase catalytic subunit [Arab

Phase competition by design in R0.5Ba0.5MnO3

Science.gov (United States)

Nowadnick, Elizabeth; He, Jiangang; Fennie, Craig

Phase competition between distinct ground states can arise from interactions on similar energy scales between the spin, charge, lattice, and orbital degrees of freedom. This competition can result in large responses to external perturbations. For example, the colossal magnetoresistance effect in the rare-earth manganites R1-xAxMnO3 arises out of competing ferromagnetic metallic and charge/orbital-ordered antiferromagnetic insulating states. Phase competition between polar and magnetic ground states is a promising strategy to realize polarization (magnetization) control with a magnetic (electric) field, which is major goal in multiferroics research. In this regard, the half-doped A-site ordered manganite Sm0.5Ba0.5MnO3 is of particular interest, because the charge/orbital-ordered antiferromagnetic insulating state in this material is polar. We use a combination of group theoretic methods and first-principles calculations to elucidate the origin of this polar state, and show that epitaxial strain can tune the material to a regime where there is a strong competition between the polar insulating state and the ferromagnetic metallic state. We then explore how to achieve electric and magnetic field control of the order parameters in this system.

R2R - software to speed the depiction of aesthetic consensus RNA secondary structures

Directory of Open Access Journals (Sweden)

Weinberg Zasha

2011-01-01

Full Text Available Abstract Background With continuing identification of novel structured noncoding RNAs, there is an increasing need to create schematic diagrams showing the consensus features of these molecules. RNA structural diagrams are typically made either with general-purpose drawing programs like Adobe Illustrator, or with automated or interactive programs specific to RNA. Unfortunately, the use of applications like Illustrator is extremely time consuming, while existing RNA-specific programs produce figures that are useful, but usually not of the same aesthetic quality as those produced at great cost in Illustrator. Additionally, most existing RNA-specific applications are designed for drawing single RNA molecules, not consensus diagrams. Results We created R2R, a computer program that facilitates the generation of aesthetic and readable drawings of RNA consensus diagrams in a fraction of the time required with general-purpose drawing programs. Since the inference of a consensus RNA structure typically requires a multiple-sequence alignment, the R2R user annotates the alignment with commands directing the layout and annotation of the RNA. R2R creates SVG or PDF output that can be imported into Adobe Illustrator, Inkscape or CorelDRAW. R2R can be used to create consensus sequence and secondary structure models for novel RNA structures or to revise models when new representatives for known RNA classes become available. Although R2R does not currently have a graphical user interface, it has proven useful in our efforts to create 100 schematic models of distinct noncoding RNA classes. Conclusions R2R makes it possible to obtain high-quality drawings of the consensus sequence and structural models of many diverse RNA structures with a more practical amount of effort. R2R software is available at http://breaker.research.yale.edu/R2R and as an Additional file.

R2R - software to speed the depiction of aesthetic consensus RNA secondary structures

Science.gov (United States)

2011-01-01

Background With continuing identification of novel structured noncoding RNAs, there is an increasing need to create schematic diagrams showing the consensus features of these molecules. RNA structural diagrams are typically made either with general-purpose drawing programs like Adobe Illustrator, or with automated or interactive programs specific to RNA. Unfortunately, the use of applications like Illustrator is extremely time consuming, while existing RNA-specific programs produce figures that are useful, but usually not of the same aesthetic quality as those produced at great cost in Illustrator. Additionally, most existing RNA-specific applications are designed for drawing single RNA molecules, not consensus diagrams. Results We created R2R, a computer program that facilitates the generation of aesthetic and readable drawings of RNA consensus diagrams in a fraction of the time required with general-purpose drawing programs. Since the inference of a consensus RNA structure typically requires a multiple-sequence alignment, the R2R user annotates the alignment with commands directing the layout and annotation of the RNA. R2R creates SVG or PDF output that can be imported into Adobe Illustrator, Inkscape or CorelDRAW. R2R can be used to create consensus sequence and secondary structure models for novel RNA structures or to revise models when new representatives for known RNA classes become available. Although R2R does not currently have a graphical user interface, it has proven useful in our efforts to create 100 schematic models of distinct noncoding RNA classes. Conclusions R2R makes it possible to obtain high-quality drawings of the consensus sequence and structural models of many diverse RNA structures with a more practical amount of effort. R2R software is available at http://breaker.research.yale.edu/R2R and as an Additional file. PMID:21205310

R2R--software to speed the depiction of aesthetic consensus RNA secondary structures.

Science.gov (United States)

Weinberg, Zasha; Breaker, Ronald R

2011-01-04

With continuing identification of novel structured noncoding RNAs, there is an increasing need to create schematic diagrams showing the consensus features of these molecules. RNA structural diagrams are typically made either with general-purpose drawing programs like Adobe Illustrator, or with automated or interactive programs specific to RNA. Unfortunately, the use of applications like Illustrator is extremely time consuming, while existing RNA-specific programs produce figures that are useful, but usually not of the same aesthetic quality as those produced at great cost in Illustrator. Additionally, most existing RNA-specific applications are designed for drawing single RNA molecules, not consensus diagrams. We created R2R, a computer program that facilitates the generation of aesthetic and readable drawings of RNA consensus diagrams in a fraction of the time required with general-purpose drawing programs. Since the inference of a consensus RNA structure typically requires a multiple-sequence alignment, the R2R user annotates the alignment with commands directing the layout and annotation of the RNA. R2R creates SVG or PDF output that can be imported into Adobe Illustrator, Inkscape or CorelDRAW. R2R can be used to create consensus sequence and secondary structure models for novel RNA structures or to revise models when new representatives for known RNA classes become available. Although R2R does not currently have a graphical user interface, it has proven useful in our efforts to create 100 schematic models of distinct noncoding RNA classes. R2R makes it possible to obtain high-quality drawings of the consensus sequence and structural models of many diverse RNA structures with a more practical amount of effort. R2R software is available at http://breaker.research.yale.edu/R2R and as an Additional file.

Estudo comparativo entre bupivacaína a 0,5% e mistura enantiomérica de bupivacaína (S75-R25 a 0,5% em anestesia peridural Estudio comparativo entre bupivacaína a 0,5% y mezcla enantiomérica de bupivacaína (S75-R25 a 0,5% en anestesia peridural Comparative study between 0.5% bupivacaine and 0.5% enantiomeric mixture of bupivacaine (S75-R25 in epidural anesthesia

Directory of Open Access Journals (Sweden)

Rosane Fossatti Gonçalves

2003-04-01

Full Text Available JUSTIFICATIVA E OBJETIVOS: A mistura enantiomérica de bupivacaína (S75-R25 vem sendo empregada pela sua propriedade anestésica com menor toxicidade do que a bupivacaína racêmica. O objetivo deste estudo é comparar a bupivacaína a 0,5% com a mistura enantiomérica de bupivacaína a 0,5% (S75-R25 em anestesia peridural. MÉTODO: Foram incluídos no estudo 44 pacientes divididos em dois grupos (n=22 denominados de Bupivacaína e S75-R25. Os pacientes foram medicados com midazolam por via venosa. A anestesia peridural foi realizada no espaço L3-L4 ou L2-L3, e administrado 16 a 24 ml da solução do anestésico local. O grupo Bupivacaína recebeu bupivacaína a 0,5% com vasoconstritor. O grupo S75-R25 recebeu a mistura enantiomérica de bupivacaína a 0,5% com vasoconstritor. Foram avaliados a temperatura do membro inferior antes e após o bloqueio peridural, o tempo de latência do bloqueio, o tipo de alteração referida pelo paciente, possíveis falhas sensoriais, nível sensorial metamérico e o grau de bloqueio motor. Na sala de recuperação pós-anestésica, foi anotado o tempo de requisição do primeiro analgésico. RESULTADOS: Fizeram parte da avaliação final 41 pacientes. Os grupos foram demograficamente semelhantes. A dose per-operatória de midazolam, o volume de anestésico local por via peridural, o tempo de latência para a instalação do bloqueio, falhas sensoriais a picada da agulha, temperatura do membro inferior nos diferentes tempos, o tipo de sensação parestésica, e o nível anestésico em dermátomos foram semelhantes entre os grupos. O grau de bloqueio motor foi mais intenso para o grupo Bupivacaína, comparado ao grupo S75-R25 (p = 0,0117. O tempo para requisição do primeiro analgésico no período pós-operatório foi superior para o grupo S75-R25, comparado ao grupo Bupivacaína (596 ± 436 minutos versus 463 ± 270 minutos, respectivamente; p = 0,04572. A incidência de efeitos adversos foi semelhante entre

IEA-R1 primary and secondary coolant piping systems coupled stress analysis

International Nuclear Information System (INIS)

Fainer, Gerson; Faloppa, Altair A.; Oliveira, Carlos A.; Mattar Neto, Miguel

2013-01-01

The aim of this work is to perform the stress analysis of a coupled primary and secondary piping system of the IEA-R1 based on tridimensional model, taking into account the as built conditions. The nuclear research reactor IEA-R1 is a pool type reactor projected by Babcox-Willcox, which is operated by IPEN since 1957. The operation to 5 MW power limit was only possible after the conduction of life management and modernization programs in the last two decades. In these programs the components of the coolant systems, which are responsible for the water circulation into the reactor core to remove the heat generated inside it, were almost totally refurbished. The changes in the primary and secondary systems, mainly the replacement of pump and heat-exchanger, implied in piping layout modifications, and, therefore, the stress condition of the piping systems had to be reanalyzed. In this paper the structural stress assessment of the coupled primary and secondary piping systems is presented and the final results are discussed. (author)

Synthesis and characterization of the novel rare earth orthophosphates Y0.5Er0.5PO4 and Y0.5Yb0.5PO4

International Nuclear Information System (INIS)

Schildhammer, Daniel; Petschnig, Lucas L.; Fuhrmann, Gerda; Heymann, Gunter; Schottenberger, Herwig; Huppertz, Hubert; Tribus, Martina

2016-01-01

The new mixed rare earth (RE) orthophosphates Y 0.5 Er 0.5 PO 4 and Y 0.5 Yb 0.5 PO 4 were synthesized by a classical solid state reaction in an electrical furnace at 1200 C. As starting materials, the corresponding rare earth oxides and diammonium hydrogen phosphate were used. The powder diffraction analyses revealed that the new compounds Y 0.5 Er 0.5 PO 4 and Y 0.5 Yb 0.5 PO 4 crystallize in a zircon-type structure being isostructural with the rare earth orthophosphate YPO 4 . Y 0.5 Er 0.5 PO 4 and Y 0.5 Yb 0.5 PO 4 crystallize in the tetragonal space group I4 1 /amd (no. 141) with four formula units in the unit cell. The structural parameters based on Rietveld refinements are a = 687.27(2), c = 601.50(2) pm, V = 0.28412(1) nm 3 , R p = 0.0143, and R wp = 0.0186 (all data) for Y 0.5 Er 0.5 PO 4 and a = 684.61(2), c = 599.31(2) pm, V = 0.28089(2) nm 3 , R p = 0.0242, and R wp = 0.0313 (all data) for Y 0.5 Yb 0.5 PO 4 . Furthermore, the structure of Y 0.5 Er 0.5 PO 4 was refined from single-crystal X-ray diffraction data: a = 687.78(5), c = 601.85(4) pm, V = 0.28470(5) nm 3 , R 1 = 0.0165, and wR 2 = 0.0385 (all data). In both compounds, the rare earth metal ions are eightfold coordinated by oxygen atoms, forming two unique interlocking tetrahedra with two individual RE-O distances. The tetrahedral phosphate groups [PO 4 ] 3- are slightly distorted in both compounds. The individual rare earth ions share a common position (Wyckoff site 4a). The presence of two rare earth ions in the structures of the new orthophosphates Y 0.5 Er 0.5 PO 4 and Y 0.5 Yb 0.5 PO 4 was additionally confirmed by single-crystal EDX spectroscopy revealing a ratio of 1:1.

78 FR 35038 - Determination That CORDRAN (Flurandrenolide) Ointment USP, 0.025% and 0.05%, Were Not Withdrawn...

Science.gov (United States)

2013-06-11

... been discontinued from marketing for reasons other than safety or effectiveness. ANDAs that refer to... Reasons of Safety or Effectiveness AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The...% and 0.05%, were not withdrawn from sale for reasons of safety or effectiveness. This determination...

Diseño de una formulación de ketotifeno 0,025 % colirio Design of a Ketotifen formula: 0.025 % eyedrops

Directory of Open Access Journals (Sweden)

Yenilen Troche Concepción

2010-06-01

Full Text Available El colirio de ketotifeno se indica para aliviar los signos y síntomas de las conjuntivitis alérgicas, por ser este un potente antihistamínico H1 que muestra cierta capacidad para inhibir la liberación de histamina y otros mediadores en mastocitos. El objetivo del presente trabajo consistió en realizar el desarrollo tecnológico del colirio de ketotifeno 0,025 %, de producción nacional teniendo en cuenta que es un medicamento muy utilizado en la "Operación Milagro", en la cual participa la República de Cuba, para lo que se hace un diseño y los estudios de preformulación. Se estudió además, las especificaciones de calidad de la formulación seleccionada, la estabilidad del producto y el tiempo de vigencia de este. Se realizó el estudio de estabilidad acelerado y por vida de estante, para lo cual se emplearon 3 lotes del producto a escala piloto. El colirio resultó estable física, química y microbiológicamente envasado en frascos de polietileno de baja densidad, por espacio de 12 meses a temperatura ambienteThe Ketotifen eyedrops is prescribed to relieve the signs and symptoms of allergic conjunctivitis due to it is a powerful H1 antihistaminic with certain ability to inhibit the histamine release and other mediators in the case of mast cells. The aim of present paper was to perform the technological development of 0.025 % eyedrops Ketotifen of national production considering that it is a drug very used in the "Operación Milagro" with participation of the Republic of Cuba and with its own design and the pre-formula. Also, we studied the selected formula specifications, the product stability and its expiry date. An accelerated stability study was conducted and by shelf life using 3 batches of pilot scale product. The eyedrops was physically, chemically and microbiologically stable when it is bottling in low-density polyethylene flasks during 12 months at room temperature.

Motor correlates of models of secondary bilateral synchrony and multiple epileptic foci

Czech Academy of Sciences Publication Activity Database

Jiruška, Přemysl; Prokš, J.; Otáhal, Jakub; Mareš, Pavel

2007-01-01

Roč. 16, č. 7 (2007), s. 627-635 ISSN 1059-1311 R&D Projects: GA ČR(CZ) GA309/03/0770; GA ČR GA304/05/2582 Institutional research plan: CEZ:AV0Z5011922 Keywords : epileptic foci * secondary bilateral synchrony * neocortex Subject RIV: ED - Physiology Impact factor: 1.815, year: 2007

Efecto del BiFeO3 en las propiedades del sistema ferroeléctrico libre de plomo K0.5Na0.5NbO3

Directory of Open Access Journals (Sweden)

Pinza, Billy N.

2014-10-01

Full Text Available In order to obtain a multiferroic material, powders and ceramic pieces, of the lead-free ferroelectric (1-x-x K0.5Na0.5NbO3 (Bi0.8La0.2FeO3 (KNN-BLFO (x = 0.005, 0.010, 0.015, 0.020, 0.025 system were prepared using the combustion reaction method. For all the studied perovskite phase, stoichiometries feature KNN was obtained. Using characterisation techniques, it was determined that the BLFO is incorporated in the crystal structure of KNN without modifying present a phase transition. Moreover, It was also proved that the addition of the BLFO to KNN, alters the particle size of the obtained powders and generates magnetic behavior in this ferroelectric.En la búsqueda de un material multiferroico, se prepararon polvos y piezas cerámicas del sistema ferroeléctrico libre de plomo (1-xK0.5Na0.5NbO3-x(Bi0.8La0.2FeO3 (KNN-BLFO (x=0.005, 0.010, 0.015, 0.020, 0.025, mediante el método de reacción por combustión. Para todas las estequiometrias estudiadas se obtuvo la fase perovskita característica del KNN. Con las diferentes caracterizaciones se determinó que el BLFO se incorpora en la estructura cristalina del KNN modificándola sin que se presente una transición de fase. Se comprobó además que la adición del BLFO al KNN, altera el tamaño de partícula de los polvos obtenidos y genera comportamiento magnético en este ferroeléctrico.

Secondary structure and phylogeny of Staphylococcus and Micrococcus 5S rRNAs.

Science.gov (United States)

Dekio, S; Yamasaki, R; Jidoi, J; Hori, H; Osawa, S

1984-01-01

Nucleotide sequences of 5S rRNAs from four bacteria, Staphylococcus aureus Smith (diffuse), Staphylococcus epidermidis ATCC 14990, Micrococcus luteus ATCC 9341 and Micrococcus luteus ATCC 4698, were determined. The secondary structural models of S. aureus and S. epidermidis sequences showed characteristics of the gram-positive bacterial 5S rRNA (116-N type [H. Hori and S. Osawa, Proc. Natl. Acad. Sci. U.S.A. 76:381-385, 1979]). Those of M. luteus ATCC 9341 and M. luteus ATCC 4698 together with that of Streptomyces griseus (A. Simoncsits, Nucleic Acids Res. 8:4111-4124, 1980) showed intermediary characteristics between the gram-positive and gram-negative (120-N type [H. Hori and S. Osawa, 1979]) 5S rRNAs. This and previous studies revealed that there exist at least three major groups of eubacteria having distinct 5S rRNA and belonging to different stems in the 5S rRNA phylogenic tree. PMID:6735981

Bupivacaína racêmica a 0,5% e mistura com excesso enantiomérico de 50% (S75-R25 a 0,5% no bloqueio do plexo braquial para cirurgia ortopédica. Estudo comparativo Bupivacaína racémica a 0,5% y mezcla con exceso enantiomérico del 50% (S75-R25 a 0,5% en el bloqueo del plexo braquial para cirugía ortopédica. Estudio comparativo Comparative study of 0.5% racemic bupivacaine versus enantiomeric mixture (S75-R25 of 0.5% bupivacaine in brachial plexus block for orthopedic surgery

Directory of Open Access Journals (Sweden)

Roberto Tsuneo Cervato Sato

2005-04-01

Full Text Available JUSTIFICATIVA E OBJETIVOS: Com a finalidade de encontrar uma droga mais segura que a bupivacaína racêmica, vários estudos foram realizados com seus isômeros. Este estudo tem como objetivo avaliar a eficácia da mistura com excesso enantiomérico de 50% (MEE50% de bupivacaína (S75-R25 a 0,5% comparada a da bupivacaína racêmica a 0,5% no bloqueio do plexo braquial, em pacientes submetidos à cirurgia ortopédica de membros superiores. MÉTODO: Participaram deste estudo, aleatório e duplamente encoberto, 40 pacientes, com idade entre 18 e 90 anos, estado físico ASA I e II, submetidos à cirurgia ortopédica de membros superiores, distribuídos em dois grupos: Grupo R, que recebeu a solução de bupivacaína racêmica a 0,5%, e Grupo L, que recebeu a solução da mistura com excesso enantiomérico de 50% de bupivacaína (S75-R25 a 0,5%, ambas com epinefrina 1:200.000 e num volume de 0,6 mL.kg-1 (3 mg.kg-1, limitados a 40 mL. Foram investigadas as características motoras e/ou sensoriais de cada nervo envolvido (nervos musculocutâneo, radial, mediano, ulnar e cutâneo medial do antebraço, bem como a incidência de efeitos colaterais. RESULTADOS: Não houve diferença estatística significativa em relação aos aspectos demográficos. Os parâmetros hemodinâmicos foram semelhantes entre os grupos, mas a pressão arterial sistólica foi maior no Grupo R. Não houve diferença significativa em relação ao tempo necessário para atingir a maior intensidade dos bloqueios motor e sensitivo. Com uma exceção, a latência do bloqueio motor do grupo muscular inervado pelo n. ulnar foi maior no Grupo L (10,75 versus 14,25 minutos. CONCLUSÕES: Em ambos os grupos foram observados adequados bloqueios motor e sensitivo para a realização da cirurgia, com poucos efeitos colaterais, sugerindo que a mistura com excesso enantiomérico de 50% de bupivacaína (S75-R25 a 0,5% com epinefrina é segura e efetiva para o bloqueio do plexo braquial para

Synthesis and characterization of the novel rare earth orthophosphates Y{sub 0.5}Er{sub 0.5}PO{sub 4} and Y{sub 0.5}Yb{sub 0.5}PO{sub 4}

Energy Technology Data Exchange (ETDEWEB)

Schildhammer, Daniel; Petschnig, Lucas L.; Fuhrmann, Gerda; Heymann, Gunter; Schottenberger, Herwig; Huppertz, Hubert [Innsbruck Univ. (Austria). Inst. fuer Allgemeine, Anorganische und Theoretische Chemie; Tribus, Martina [Innsbruck Univ. (Austria). Inst. fuer Mineralogie und Petrographie

2016-02-01

The new mixed rare earth (RE) orthophosphates Y{sub 0.5}Er{sub 0.5}PO{sub 4} and Y{sub 0.5}Yb{sub 0.5}PO{sub 4} were synthesized by a classical solid state reaction in an electrical furnace at 1200 C. As starting materials, the corresponding rare earth oxides and diammonium hydrogen phosphate were used. The powder diffraction analyses revealed that the new compounds Y{sub 0.5}Er{sub 0.5}PO{sub 4} and Y{sub 0.5}Yb{sub 0.5}PO{sub 4} crystallize in a zircon-type structure being isostructural with the rare earth orthophosphate YPO{sub 4}. Y{sub 0.5}Er{sub 0.5}PO{sub 4} and Y{sub 0.5}Yb{sub 0.5}PO{sub 4} crystallize in the tetragonal space group I4{sub 1}/amd (no. 141) with four formula units in the unit cell. The structural parameters based on Rietveld refinements are a = 687.27(2), c = 601.50(2) pm, V = 0.28412(1) nm{sup 3}, R{sub p} = 0.0143, and R{sub wp} = 0.0186 (all data) for Y{sub 0.5}Er{sub 0.5}PO{sub 4} and a = 684.61(2), c = 599.31(2) pm, V = 0.28089(2) nm{sup 3}, R{sub p} = 0.0242, and R{sub wp} = 0.0313 (all data) for Y{sub 0.5}Yb{sub 0.5}PO{sub 4}. Furthermore, the structure of Y{sub 0.5}Er{sub 0.5}PO{sub 4} was refined from single-crystal X-ray diffraction data: a = 687.78(5), c = 601.85(4) pm, V = 0.28470(5) nm{sup 3}, R{sub 1} = 0.0165, and wR{sub 2} = 0.0385 (all data). In both compounds, the rare earth metal ions are eightfold coordinated by oxygen atoms, forming two unique interlocking tetrahedra with two individual RE-O distances. The tetrahedral phosphate groups [PO{sub 4}]{sup 3-} are slightly distorted in both compounds. The individual rare earth ions share a common position (Wyckoff site 4a). The presence of two rare earth ions in the structures of the new orthophosphates Y{sub 0.5}Er{sub 0.5}PO{sub 4} and Y{sub 0.5}Yb{sub 0.5}PO{sub 4} was additionally confirmed by single-crystal EDX spectroscopy revealing a ratio of 1:1.

Systematics of Penicillium simplicissimum based on rDNA sequences, morphology and secondary metabolites

DEFF Research Database (Denmark)

Tuthill, D.E.; Frisvad, Jens Christian; Christensen, M.

2001-01-01

supported by differences in micromorphological characters, particularly of the conidia and phialides, and the production of distinct profiles of secondary metabolites by each species. Group-I introns, located in the SSU rDNA, were identified in six of the 21 isolates; their presence was used to test...

Crystal structure of Mo/sub 0.975/Ti/sub 0.025/O2 between 24 and 9000C

International Nuclear Information System (INIS)

Ghedira, M.; Do-Dinh, C.; Marezio, M.; Mercier, J.

1985-01-01

Structure of Mo/sub 0.975/Ti/sub 0.025/O 2 has been refined from single-crystal X-ray data at room temperature, 300, 500, 700, and 900 0 C. The variation of the lattice parameters as a function of temperature has been measured up to 1100 0 C. The existence of the Mo-Mo bonds of second order across the shared octahedral edge is confirmed. The bond strength-bond length method of Zachariasen gives the correct valence for the cations, but yields 2.168 for O(1) and 1.832 for O(2). These unreal charges are attributed to the presence of the Mo-Mo double bonds. The same calculation applied to the isostructural VO 2 gives the correct valences for all atoms. The structure of Mo/sub 0.975/Ti/sub 0.025/O 2 remains almost unchanged up to 900 0 C. The observed small variations indicate that at a temperature higher than 1100 0 C, Mo/sub 0.975/Ti/sub 0.025/O 2 should undergo a phase transition where the double bonds would become either single or be broken completely, in which case the tetragonal rutile structure would be obtained. 11 references, 2 figures, 5 tables

Diminuição da progressão da miopia com atropina 0,025%

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Celso Marcelo da Cunha

Full Text Available Resumo Objetivo: Demonstrar a eficácia do uso do colírio de atropina 0,025% em crianças míopes, no Brasil, para a diminuição da progressão da miopia. Métodos: Realizou-se estudo prospectivo em 60 pacientes do Hospital Geral Universitário e Oftalmocenter Santa Rosa - Cuiabá - MT, com idades entre 6 e 12 anos, com equivalente esférico da refração entre -1,00 a -6,00 DE, refração cilíndrica < -1,00 DC e taxa de progressão anual de 0,50 DE (ou maior. Efetuou-se exame oftalmológico geral, topografia corneana e a medida do diâmetro anteroposterior do globo ocular (DAP. Os pacientes foram divididos em dois grupos: em que o Grupo 1 recebeu colírio de atropina 0,025%, todas as noites, e prescreveu-se a refração total com lentes com antirreflexo de multicamadas; e, no Grupo 2, somente a refração total. Nova avaliação foi realizada dois anos após. O teste T Student pareado foi utilizado para comparações das refrações, DAP e ceratometrias, medidas no exame inicial e no exame com 2 anos de seguimento. Resultados: Das 60 crianças, 30 eram do Grupo 1 com idade média de 8,21 ± 1,72 anos, e as do grupo controle com idade média de 8,17 ± 1,73 anos. Quatorze (46,66% e 16 (53,33% eram do sexo masculino nos Grupos 1 e 2, respectivamente. O Grupo 1 revelou menor progressão da miopia (Grupo 1: 0,43 ± 0,19D, Grupo 2: 1,24 ± 0,37D e menor crescimento do DAP em relação ao grupo controle (Grupo 1: 0,19 ± 0,09mm, Grupo 2: 0,48 ± 0,12mm. Houve diferença estatisticamente significativa (P<0,05 entre o grupo tratado e o controle em relação à refração e ao crescimento DAP. A topografia não teve mudança estatisticamente significativa. Conclusão: A atropina em baixas concentrações foi eficaz em diminuir a progressão da miopia em 65% desta população estudada, por 2 anos. No entanto estudos com maior número de participantes e em diversas regiões do Brasil poderiam demonstrar melhor esse fato.

Chiral auxiliary-mediated enantioenrichment of (+-)-ibuprofen, under Steglich conditions, with secondary alcohols derived from (R)-carvone

Energy Technology Data Exchange (ETDEWEB)

Amongero, Marcela; Visnovezky, Damian; Kaufman, Teodoro S., E-mail: kaufman@iquir-conicet.gov.a [Instituto de Quimica Rosario (IQUIR, CONICET-UNR) (Argentina); Universidad Nacional de Rosario (Argentina)

2010-07-01

The synthesis of a series of chiral secondary alcohols derived from (R)-carvone, and the stereochemical outcome of their reaction with (+-)-ibuprofen, is reported. The racemic drug was transformed into the corresponding diastereomeric esters mediated by DCC/DMAP, affording up to 5.7:1 diastereomeric ratios of the esters derived from either (S)- or (R)-ibuprofen, depending on the type of chiral auxiliary employed. (author)

Chiral auxiliary-mediated enantioenrichment of (+-)-ibuprofen, under Steglich conditions, with secondary alcohols derived from (R)-carvone

International Nuclear Information System (INIS)

Amongero, Marcela; Visnovezky, Damian; Kaufman, Teodoro S.

2010-01-01

The synthesis of a series of chiral secondary alcohols derived from (R)-carvone, and the stereochemical outcome of their reaction with (±)-ibuprofen, is reported. The racemic drug was transformed into the corresponding diastereomeric esters mediated by DCC/DMAP, affording up to 5.7:1 diastereomeric ratios of the esters derived from either (S)- or (R)-ibuprofen, depending on the type of chiral auxiliary employed. (author)

Bupivacaína levógira a 0,5% pura versus mistura enantiomérica de bupivacaína (S75-R25 a 0,5% em anestesia peridural para cirurgia de varizes Bupivacaína levógira a 0,5% pura versus mezcla enantiomerica bupivacaína (S75-R25 a 0,5% en anestesia peridural para cirugía de várices Plain 0.5% levogyrous bupivacaine versus 0.5% bupivacaine enantiomeric mixture (S75-R25 in epidural anesthesia for varicose vein surgery

Directory of Open Access Journals (Sweden)

José Delfino

2001-12-01

Full Text Available JUSTIFICATIVA E OBJETIVOS: A cardiotoxicidade da bupivacaína racêmica (50:50 ainda é a grande variável relacionada à segurança de indicação nos bloqueios regionais que exigem massas e volumes elevados. Recentes experimentações em animais sugerem que a modificação da relação enantiomérica da bupivacaína racêmica poderia contribuir para sua eficácia terapêutica e diminuição de sua toxicidade potencial. O objetivo do presente estudo foi comparar a eficiência da mistura enantiomérica de bupivacaína (S75-R25 com a levógira pura S(-100 na anestesia peridural lombar para cirurgias de varizes dos membros inferiores. MÉTODO: O estudo envolveu 30 pacientes do sexo feminino com idades entre 15 e 65 anos, estado físico ASA I ou II, programados para cirurgia eletiva de varizes. Em teste aleatório e duplamente encoberto, os pacientes foram divididos em dois grupos de 15: Grupo S75-R25 - 20 ml (100 mg de mistura enantiomérica de bupivacaína a 0,5% (S75-R25 - e Grupo Levógiro - 20 ml (100 mg de bupivacaína levógira S(-100% a 0,5% sem adjuvante. Foram comparadas as características dos bloqueios sensitivo e motor bem como a incidência de efeitos colaterais. RESULTADOS: Foram detectadas diferenças intergrupais relacionadas às características demográficas e um maior tempo cirúrgico no grupo S75-R25. A dispersão mais rápida e a menor potência analgésica da mistura isomérica exibiram significância estatística. Não houve diferença significativa relacionada à ocorrência de efeitos colaterais. O grupo levógiro apresentou menor relaxamento muscular. CONCLUSÕES: A redução da incidência de efeitos colaterais, a receptividade do método pelos pacientes, a ausência de sintomatologia neurológica transitória pós-operatória apontam para a aplicação segura de ambas as soluções em anestesia peridural lombar para cirurgia de varizes dos membros inferiores. A casuística, entretanto, não é ainda suficiente para

Pressure-induced structural and semiconductor-semiconductor transitions in C o0.5M g0.5C r2O4

Science.gov (United States)

Rahman, S.; Saqib, Hajra; Zhang, Jinbo; Errandonea, D.; Menéndez, C.; Cazorla, C.; Samanta, Sudeshna; Li, Xiaodong; Lu, Junling; Wang, Lin

2018-05-01

The effect of pressure on the structural, vibrational, and electronic properties of Mg-doped Cr bearing spinel C o0.5M g0.5C r2O4 was studied up to 55 GPa at room-temperature using x-ray diffraction, Raman spectroscopy, electrical transport measurements, and ab initio calculations. We found that the ambient-pressure phase is cubic (spinel-type, F d 3 ¯m ) and underwent a pressure-induced structural transition to a tetragonal phase (space group I 4 ¯m 2 ) above 28 GPa. The ab initio calculation confirmed this first-order phase transition. The resistivity of the sample decreased at low pressures with the existence of a low-pressure (LP) phase and started to increase with the emergence of a high-pressure (HP) phase. The temperature dependent resistivity experiments at different pressures illustrated the wide band gap semiconducting nature of both the LP and HP phases with different activation energies, suggesting a semiconductor-semiconductor transition at HP. No evidence of chemical decomposition or a semiconductor-metal transition was observed in our studies.

Procedure and composition for secondary recovery of petroleum

Energy Technology Data Exchange (ETDEWEB)

Sullivan, F F

1968-03-04

A copolymer of vinyl methyl ether and maleic anhydride in a brine (sodium bicarbonate, sodium chloride, calcium chloride) was proposed, for secondary oil recovery in the presence of clays. The ratio of copolymer to salts should be 20 : 1 to 1 : 1500. The ratio between the multivalent salts and sodium bicarbonate is 5 : 1 to 1 : 600. The concentration of salts of multivalent cations should be present in the range of 0.0025 to 0.25% by weight. Alkali metal halides comprise 0.1 to 1% of the polymer solution.

The secondary structure of large-subunit rRNA divergent domains, a marker for protist evolution

DEFF Research Database (Denmark)

Lenaers, G; Nielsen, Henrik; Engberg, J

1988-01-01

The secondary structure of the large-subunit ribosomal RNA (24-26S rRNA) has been studied with emphasis on comparative analysis of the folding patterns of the divergent domains in the available protist sequences, that is Prorocentrum micans (dinoflagellate), Saccharomyces carlsbergensis (yeast......), Tetrahymena thermophila (ciliate), Physarum polycephalum and Dictyostelium discoideum (slime moulds), Crithidia fasciculata and Giardia lamblia (parasitic flagellates). The folding for the D3, D7a and D10 divergent domains has been refined and a consensus model for the protist 24-26S rRNA structure...

An updated 18S rRNA phylogeny of tunicates based on mixture and secondary structure models

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Shenkar Noa

2009-08-01

Full Text Available Abstract Background Tunicates have been recently revealed to be the closest living relatives of vertebrates. Yet, with more than 2500 described species, details of their evolutionary history are still obscure. From a molecular point of view, tunicate phylogenetic relationships have been mostly studied based on analyses of 18S rRNA sequences, which indicate several major clades at odds with the traditional class-level arrangements. Nonetheless, substantial uncertainty remains about the phylogenetic relationships and taxonomic status of key groups such as the Aplousobranchia, Appendicularia, and Thaliacea. Results Thirty new complete 18S rRNA sequences were acquired from previously unsampled tunicate species, with special focus on groups presenting high evolutionary rate. The updated 18S rRNA dataset has been aligned with respect to the constraint on homology imposed by the rRNA secondary structure. A probabilistic framework of phylogenetic reconstruction was adopted to accommodate the particular evolutionary dynamics of this ribosomal marker. Detailed Bayesian analyses were conducted under the non-parametric CAT mixture model accounting for site-specific heterogeneity of the evolutionary process, and under RNA-specific doublet models accommodating the occurrence of compensatory substitutions in stem regions. Our results support the division of tunicates into three major clades: 1 Phlebobranchia + Thaliacea + Aplousobranchia, 2 Appendicularia, and 3 Stolidobranchia, but the position of Appendicularia could not be firmly resolved. Our study additionally reveals that most Aplousobranchia evolve at extremely high rates involving changes in secondary structure of their 18S rRNA, with the exception of the family Clavelinidae, which appears to be slowly evolving. This extreme rate heterogeneity precluded resolving with certainty the exact phylogenetic placement of Aplousobranchia. Finally, the best fitting secondary-structure and CAT-mixture models

Final Report - LAW Envelope C Glass Formulation Testing to Increase Waste Loading, VSL-05R5900-1

Energy Technology Data Exchange (ETDEWEB)

Kruger, Albert A.; Pegg, I. L.; Matlack, K. S.; Joseph, I.; Muller, I. S.; Gong, W.

2013-12-03

This report describes the results of testing specified by Test Plan VSL-05R5900-1 Rev.0. The work was performed in compliance with the quality assurance requirements specified in the Test Plan. Results required by the Test Plan are reported. The test results and this report have been reviewed for correctness, technical adequacy, completeness, and accuracy.

The origin of high magnetic properties in (R,Zr)(Fe,Co)11.0–11.5Ti1.0–0.5Ny (y=1.0–1.4 for R=Nd, y=0 for R=Sm) compounds

International Nuclear Information System (INIS)

Kobayashi, K.; Suzuki, S.; Kuno, T.; Urushibata, K.; Sakuma, N.; Yano, M.; Shoji, T.; Kato, A.; Manabe, A.

2017-01-01

Ten alloys and nitrogenated compounds of (R,Zr)(Fe,Co) 11.0–11.5 Ti 1.0–0.5 N y (y=1.0–1.4 for R=Nd, y=0 for R=Sm) with a ThMn 12 -type structure were prepared. The average Fe–Fe interatomic distances, d(Fe–Fe), for Fe sites were calculated based on the reported atomic parameters. The hyperfine splittings (inner field (IF), in teslas) were measured by Mössbauer spectroscopy, and the IF increased with increasing d(Fe–Fe) for Fe sites, indicating a magneto-volume effect. The order of IF magnitude in Fe sites was Fe(8i)>Fe(8j)>Fe(8f) in all alloys. Co substitution for Fe sites, (Fe 0.75 Co 0.25 ), increased the IF by 25% for the R=Nd alloy and 15% for the R=Sm alloy. Decreasing Ti content from −Ti 1.0 to −Ti 0.5 , which increased the Fe and Co content, preserved the ThMn 12 structure with Zr substitution for R(2a) sites, and caused a slight increase in the IF of 2% for the R=Nd alloy and 7% for the R=Sm alloy. Nitrogenation, where N was introduced into the 2b sites, also increased IF in R=Nd alloys, by 23% for the Co- and Zr-free alloys, NdFe 11 Ti 1.0 N 1.5 , and by 7% for the Co-containing, (Nd 0.7 Zr 0.3 ) (Fe 0.75 Co 0.25 ) 11.5 Ti 0.5 N 1.3 alloy. The IF values of the R=Nd alloys were slightly larger than those of the R=Sm alloys. In conclusion, the magneto-volume effect was clearly observed at the Fe sites, and Co substitution into Fe sites and nitrogenation (R=Nd alloys) compensated for the increased IF. Increasing the Fe and Co fractions also increased IF slightly. - Highlights: • Average distances of Fe–Fe (d(Fe–Fe)) were calculated using lattice constants. • Hyperfine fields (IF) in Fe sites were measured using Mössbauer spectroscopy. • Relationship between d(Fe–Fe) and IF at each Fe site was obtained. • Co substitution and N introduction effects on IF was also measured. • Magneto-volume effect is main reason of IF augmentation in Fe sites.

A R2R3-MYB transcription factor that is specifically expressed in cotton (Gossypium hirsutum) fibers affects secondary cell wall biosynthesis and deposition in transgenic Arabidopsis.

Science.gov (United States)

Sun, Xiang; Gong, Si-Ying; Nie, Xiao-Ying; Li, Yang; Li, Wen; Huang, Geng-Qing; Li, Xue-Bao

2015-07-01

Secondary cell wall (SCW) is an important industrial raw material for pulping, papermaking, construction, lumbering, textiles and potentially for biofuel production. The process of SCW thickening of cotton fibers lays down the cellulose that will constitute the bulk (up to 96%) of the fiber at maturity. In this study, a gene encoding a MYB-domain protein was identified in cotton (Gossypium hirsutum) and designated as GhMYBL1. Quantitative real-time polymerase chain reaction (RT-PCR) analysis revealed that GhMYBL1 was specifically expressed in cotton fibers at the stage of secondary wall deposition. Further analysis indicated that this protein is a R2R3-MYB transcription factor, and is targeted to the cell nucleus. Overexpression of GhMYBL1 in Arabidopsis affected the formation of SCW in the stem xylem of the transgenic plants. The enhanced SCW thickening also occurred in the interfascicular fibers, xylary fibers and vessels of the GhMYBL1-overexpression transgenic plants. The expression of secondary wall-associated genes, such as CesA4, CesA7, CesA8, PAL1, F5H and 4CL1, were upregulated, and consequently, cellulose and lignin biosynthesis were enhanced in the GhMYBL1 transgenic plants. These data suggested that GhMYBL1 may participate in modulating the process of secondary wall biosynthesis and deposition of cotton fibers. © 2014 Scandinavian Plant Physiology Society.

Studies on Structural and Morphological Properties of Multidoped Ceria Ce0.8Nd0.0025Sm0.0025Gd0.005Dy0.095Y0.095O2-δ (x=0.2 as Solid Solutions

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Marija Stojmenović

2016-01-01

Full Text Available The nanopowdery solid solutions of multidoped ceria Ce0.8Nd0.0025Sm0.0025Gd0.005Dy0.095Y0.095O2-δ (x=0.2 with the fluorite type crystal structure of CeO2 were synthesized for the first time. Two synthesis procedures were applied: the modified glycine-nitrate procedure (MGNP method and room temperature self-propagating reaction (SPRT method. All nanopowders were characterized by XRPD analysis, Raman spectroscopy, low temperature nitrogen physisorption, TEM, and SEM methods. According to the XRPD and Raman spectroscopy results, single phase solid solutions of fluorite structure were evidenced regardless of the number of dopants and synthesis procedure. Both XRPD and TEM were analyses evidenced nanometer particle dimensions. The SPRT method results in obtaining sample with higher specific surface area, smaller crystallite and particles sizes, and the same values of the lattice parameter in comparison to pure CeO2. Raman spectroscopy was confirmed to the oxygen vacancies introduced into the ceria lattice when Ce4+ ions were replaced with cations (dopants of lower valence state (3+, which may indicate the potential improvement of ionic conductivity. Additionally, the presence of oxygen vacancies in the lattice ceria, as well as very developed grain boundaries, gives a new possibility for potential application of obtained nanopowders in the area of room temperature ferromagnetism as spintronics.

Studies on Structural and Morphological Properties of Multidoped Ceria Ce 0.8 Nd 0.0025 Sm 0.0025 Gd 0.005 Dy 0.095 Y 0.095 O 2 - δ ( x = 0.2 ) as Solid Solutions

KAUST Repository

Stojmenović, Marija

2016-04-17

The nanopowdery solid solutions of multidoped ceria Ce0.8Nd0.0025Sm0.0025Gd0.005Dy0.095Y0.095 () with the fluorite type crystal structure of CeO2 were synthesized for the first time. Two synthesis procedures were applied: the modified glycine-nitrate procedure (MGNP method) and room temperature self-propagating reaction (SPRT method). All nanopowders were characterized by XRPD analysis, Raman spectroscopy, low temperature nitrogen physisorption, TEM, and SEM methods. According to the XRPD and Raman spectroscopy results, single phase solid solutions of fluorite structure were evidenced regardless of the number of dopants and synthesis procedure. Both XRPD and TEM were analyses evidenced nanometer particle dimensions. The SPRT method results in obtaining sample with higher specific surface area, smaller crystallite and particles sizes, and the same values of the lattice parameter in comparison to pure CeO2. Raman spectroscopy was confirmed to the oxygen vacancies introduced into the ceria lattice when Ce4+ ions were replaced with cations (dopants) of lower valence state (3+), which may indicate the potential improvement of ionic conductivity. Additionally, the presence of oxygen vacancies in the lattice ceria, as well as very developed grain boundaries, gives a new possibility for potential application of obtained nanopowders in the area of room temperature ferromagnetism as spintronics.

Variation in secondary structure of the 16S rRNA molecule in cyanobacteria with implications for phylogenetic analysis

Czech Academy of Sciences Publication Activity Database

Řeháková, Klára; Johansen, J. R.; Bowen, M.B.; Martin, M.P.; Sheil, C.A.

2014-01-01

Roč. 14, č. 2 (2014), s. 161-178 ISSN 1802-5439 Institutional support: RVO:60077344 Keywords : 16S rRNA secondary structure * cyanobacteria * phylogeny Subject RIV: EE - Microbiology, Virology Impact factor: 1.930, year: 2014

Analysis of the offshore installations regulations 2005 (SCR05r12) within Brazilian reality; Analise da regulacao das instalacoes offshore 2005 (SCR05r12) dentro da realidade brasileira

Energy Technology Data Exchange (ETDEWEB)

Nalvarte, Gladys; Storch, Rafael; Araujo, Pedro; Oliveira, Luiz Fernando [Det Norske Veritas (Brazil)

2008-07-01

The main motivation for the present study is the modifications presented in the guidance Offshore Installations (Safety Case) Regulations 2005 (SCR05 r12), released by HSE, in relation to the Offshore Installation Regulation 1992, SCR92. A critical analysis of the new regulation issued by HSE is developed and conclusions are obtained. A cost-benefit approach applied to the Quantitative Risk Analysis (QRA), using computational fluid dynamics (CFD) techniques, is suggested. Thereby, a method to identify the mitigation measures that most reduces the risks with the minimum cost is obtained. On the other hand, this new QRA approach combined with a cost benefit analysis is intended to have a total cost diminished. In this case, the cost of the new QRA study is dependant on the number of reevaluations needed to determine the mitigation measures to be applied. (author)

Obstruction theory on 8-manifolds

Czech Academy of Sciences Publication Activity Database

Čadek, M.; Crabb, M.; Vanžura, Jiří

2008-01-01

Roč. 127, č. 2 (2008), s. 167-186 ISSN 0025-2611 R&D Projects: GA ČR GA201/05/2117 Institutional research plan: CEZ:AV0Z10190503 Keywords : 8-manifolds * obstruction theory Subject RIV: BA - General Mathematics Impact factor: 0.509, year: 2008

New polymer lithium secondary batteries based on ORMOCER (R) electrolytes-inorganic-organic polymers

DEFF Research Database (Denmark)

Popall, M.; Buestrich, R.; Semrau, G.

2001-01-01

Based on new plasticized inorganic-organic polymer electrolytes CM. Popall, M. Andrei, J. Kappel, J. Kron, K. Olma, B. Olsowski,'ORMOCERs as Inorganic-organic Electrolytes for New Solid State Lithium Batteries and Supercapacitors', Electrochim. Acta 43 (1998) 1155] new flexible foil-batteries...... electrolyte, typical for polymer electrolytes. Cycling tests (more than 900 cycles) proved that the unplasticized electrolyte can act as binder in composite cathodes of lithium secondary batteries [2]. Charge/discharge cycles of complete batteries like (Cu/active carbon/ORMOCER(R)/LiCoO2/Al) with an ORMOCER......(R) as separator electrolyte were measured. The voltage drop of these batteries is very similar to cells with standard liquid electrolytes and the efficiency is close to 100%. Cycling the batteries with a current density of 0.25 mA cm(-2) between the voltage limits of 3.1 and 4.1 V results in a charge...

Deuterium short-range order in Pd0.975Ag0.025D0.685 by diffuse neutron scattering

DEFF Research Database (Denmark)

Blaschko, O.; Klemencic, R.; Fratzl, P.

1983-01-01

By diffuse neutron scattering the D short-range order in a Pd0.975Ag0.025D0.685 crystal was investigated at 50 and 70K. The results are compared with the D ordering in the PdDx system previously investigated, and it is shown that the isointensity contours around the (1/2,1,0) point are similar...

Secondary prophylaxis with rFVIIa in hemophilia and inhibitors: Recommendations from an Experts Committee from Argentina

Directory of Open Access Journals (Sweden)

Raúl Pérez Bianco

2010-06-01

Full Text Available Secondary prophylaxis with rFVIIa has been the subject of several publications in the past few years. However, there is no general consensus on how this treatment should be put into practice, as publications have been very heterogeneous in the dosing schedule they report. Furthermore, the mechanism of action of rFVIIa and its short half life have been used as arguments against its role in prophylaxis. There have been a series of recent publications that show that rFVIIa can traffic through the intact endothelium and be stored in the subendothelium of several organs for a prolonged period of time. In order to consensuate the role of rFVIIa in prophylaxis, a group of experts from Argentina, resumed available information regarding pharmacology and clinical experience with this treatment, and developed a series of recommendations to use this drug in the prophylaxis setting.

On the spectrum of a Stokes type operator arising from flow around a rotating body

Czech Academy of Sciences Publication Activity Database

Farwig, R.; Neustupa, Jiří

2007-01-01

Roč. 122, č. 4 (2007), s. 419-437 ISSN 0025-2611 R&D Projects: GA ČR(CZ) GA201/05/0005 Institutional research plan: CEZ:AV0Z10190503 Keywords : eigenvalues * essential spectrum * modified Stokes operator Subject RIV: BA - General Mathematics Impact factor: 0.316, year: 2007

Chiral gels derived from secondary ammonium salts of (1R,3S-(+-camphoric acid

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Tapas Kumar Adalder

2010-09-01

Full Text Available In order to have access to chiral gels, a series of salts derived from (1R,3S-(+-camphoric acid and various secondary amines were prepared based on supramolecular synthon rationale. Out of seven salts prepared, two showed moderate gelation abilities. The gels were characterized by differential scanning calorimetry, table top rheology, scanning electron microscopy, single crystal and powder X-ray diffraction. Structure property correlation based on X-ray diffraction techniques remain inconclusive indicating that some of the integrated part associated with the gelation phenomena requires a better understanding.

2010 Biometrics Conference Held in Arlington, Virginia on January 20-21, 2010

Science.gov (United States)

2010-01-21

civil identification, facility/IT security and access control markets . MorphoTrak and its global parent -- Sagem Sécurité -- are leading innovators...n r s recogn t on researc since 2004 R l i   f  i e axat on o constra nts  Large open databases and challenge problems N  t h l i ew ec no og es...They happen in remote Afghan villages infiltrated by the Taliban. - They happen in crowded cities and bustling markets . p. 2 - They happen

Quantitation of base substitutions in eukaryotic 5S rRNA: selection for the maintenance of RNA secondary structure.

Science.gov (United States)

Curtiss, W C; Vournakis, J N

1984-01-01

Eukaryotic 5S rRNA sequences from 34 diverse species were compared by the following method: (1) The sequences were aligned; (2) the positions of substitutions were located by comparison of all possible pairs of sequences; (3) the substitution sites were mapped to an assumed general base pairing model; and (4) the R-Y model of base stacking was used to study stacking pattern relationships in the structure. An analysis of the sequence and structure variability in each region of the molecule is presented. It was found that the degree of base substitution varies over a wide range, from absolute conservation to occurrence of over 90% of the possible observable substitutions. The substitutions are located primarily in stem regions of the 5S rRNA secondary structure. More than 88% of the substitutions in helical regions maintain base pairing. The disruptive substitutions are primarily located at the edges of helical regions, resulting in shortening of the helical regions and lengthening of the adjacent nonpaired regions. Base stacking patterns determined by the R-Y model are mapped onto the general secondary structure. Intrastrand and interstrand stacking could stabilize alternative coaxial structures and limit the conformational flexibility of nonpaired regions. Two short contiguous regions are 100% conserved in all species. This may reflect evolutionary constraints imposed at the DNA level by the requirement for binding of a 5S gene transcription initiation factor during gene expression.

Sharpness and non-compactness of embeddings of Bessel-potential-type spaces

Czech Academy of Sciences Publication Activity Database

Gogatishvili, Amiran; Neves, J. S.; Opic, Bohumír

2007-01-01

Roč. 280, č. 10 (2007), s. 1083-1093 ISSN 0025-584X R&D Projects: GA ČR GA201/05/2033 Institutional research plan: CEZ:AV0Z10190503 Keywords : slowly varying functions * Lorentz-Karamata spaces * rearrangement-invariant Banach function spaces Subject RIV: BA - General Mathematics Impact factor: 0.415, year: 2007

[Secondary metabolites from a deep-sea-derived actinomycete Micrococcus sp. R21].

Science.gov (United States)

Peng, Kun; Su, Rui-qiang; Zhang, Gai-yun; Cheng, Xuan-xuan; Yang, Quan; Liu, Yong-hong; Yang, Xian-wen

2015-06-01

To investigate cytotoxic secondary metabolites of Micrococcus sp. R21, an actinomycete isolated from a deep-sea sediment (-6 310 m; 142 degrees 19. 9' E, 10 degrees 54. 6' N) of the Western Pacific Ocean, column chromatography was introduced over silica gel, ODS, and Sephadex LH-20. As a result, eight compounds were obtained. By mainly detailed analysis of the NMR data, their structures were elucidated as cyclo(4-hydroxy-L-Pro-L-leu) (1), cyclo(L-Pro-L-Gly) (2), cyclo( L-Pro-L-Ala) (3), cyclo( D-Pro-L-Leu) (4), N-β-acetyltryptamine (5), 2-hydroxybenzoic acid (6), and phenylacetic acid (7). Compound 1 exhibited weak cytotoxic activity against RAW264. 7 cells with IC50 value of 9.1 μmol x L(-1).

P-R-R Study Technique, Group Counselling And Gender Influence ...

African Journals Online (AJOL)

Read-Recall (P-R-R) study technique and group counselling on the academic performance of senior secondary school students. The objectives of this study were to determine the effect of Group Counselling combined with P-R-R study ...

The origin of high magnetic properties in (R,Zr)(Fe,Co){sub 11.0–11.5}Ti{sub 1.0–0.5}N{sub y} (y=1.0–1.4 for R=Nd, y=0 for R=Sm) compounds

Energy Technology Data Exchange (ETDEWEB)

Kobayashi, K., E-mail: koba@ms.sist.ac.jp [Shizuoka Institute of Science and Technology, 2200-2 Toyosawa, Fukuroi, Shizuoka 437-8555 (Japan); Suzuki, S.; Kuno, T.; Urushibata, K. [Shizuoka Institute of Science and Technology, 2200-2 Toyosawa, Fukuroi, Shizuoka 437-8555 (Japan); Sakuma, N.; Yano, M.; Shoji, T.; Kato, A. [Toyota Motor Corporation, 1200 Mishuku, Susono, Shizuoka 410-1193 (Japan); Technology Reserch Association of Magnetic Materials fot High-efficiency Motors (Mag-HEM) Higashifuji-Branch, 1200 Mishuku, Susono, Shizuoka 410-1193, Japan. (Japan); Manabe, A. [Technology Reserch Association of Magnetic Materials fot High-efficiency Motors (Mag-HEM) Higashifuji-Branch, 1200 Mishuku, Susono, Shizuoka 410-1193, Japan. (Japan)

2017-03-15

Ten alloys and nitrogenated compounds of (R,Zr)(Fe,Co){sub 11.0–11.5}Ti{sub 1.0–0.5}N{sub y} (y=1.0–1.4 for R=Nd, y=0 for R=Sm) with a ThMn{sub 12}-type structure were prepared. The average Fe–Fe interatomic distances, d(Fe–Fe), for Fe sites were calculated based on the reported atomic parameters. The hyperfine splittings (inner field (IF), in teslas) were measured by Mössbauer spectroscopy, and the IF increased with increasing d(Fe–Fe) for Fe sites, indicating a magneto-volume effect. The order of IF magnitude in Fe sites was Fe(8i)>Fe(8j)>Fe(8f) in all alloys. Co substitution for Fe sites, (Fe{sub 0.75}Co{sub 0.25}), increased the IF by 25% for the R=Nd alloy and 15% for the R=Sm alloy. Decreasing Ti content from −Ti{sub 1.0} to −Ti{sub 0.5}, which increased the Fe and Co content, preserved the ThMn{sub 12} structure with Zr substitution for R(2a) sites, and caused a slight increase in the IF of 2% for the R=Nd alloy and 7% for the R=Sm alloy. Nitrogenation, where N was introduced into the 2b sites, also increased IF in R=Nd alloys, by 23% for the Co- and Zr-free alloys, NdFe{sub 11}Ti{sub 1.0}N{sub 1.5}, and by 7% for the Co-containing, (Nd{sub 0.7}Zr{sub 0.3}) (Fe{sub 0.75}Co{sub 0.25}) {sub 11.5}Ti{sub 0.5}N{sub 1.3} alloy. The IF values of the R=Nd alloys were slightly larger than those of the R=Sm alloys. In conclusion, the magneto-volume effect was clearly observed at the Fe sites, and Co substitution into Fe sites and nitrogenation (R=Nd alloys) compensated for the increased IF. Increasing the Fe and Co fractions also increased IF slightly. - Highlights: • Average distances of Fe–Fe (d(Fe–Fe)) were calculated using lattice constants. • Hyperfine fields (IF) in Fe sites were measured using Mössbauer spectroscopy. • Relationship between d(Fe–Fe) and IF at each Fe site was obtained. • Co substitution and N introduction effects on IF was also measured. • Magneto-volume effect is main reason of IF augmentation in Fe sites.

Polyphasic characterization of Dolichospermum spp. and Sphaerospermopsis spp. (Nostocales, cyanobacteria): morphology, 16S rRNA gene sequences and fatty acid and secondary metabolite profiles

Czech Academy of Sciences Publication Activity Database

Zapomělová, Eliška; Hrouzek, Pavel; Řezanka, Tomáš; Jezberová, Jitka; Řeháková, Klára; Hisem, D.; Komárková, Jaroslava

2011-01-01

Roč. 47, č. 5 (2011), s. 1152-1163 ISSN 0022-3646 R&D Projects: GA AV ČR(CZ) KJB600960703; GA ČR(CZ) GAP504/10/1501; GA ČR(CZ) GA206/09/0309 Institutional research plan: CEZ:AV0Z60170517; CEZ:AV0Z50200510; CEZ:AV0Z60050516 Keywords : taxonomy * cyanobacteria * Anabaena * Dolichospermum * Sphaerospermopsis * phylogeny * 16S rRNA gene * fatty acids * secondary metabolites Subject RIV: EE - Microbiology, Virology Impact factor: 2.071, year: 2011

PDB: CBRC-HSAP-05-0044 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-HSAP-05-0044 2R4R,2RH1,3D4S,2R4S, Region:1-365(Identity=99%) PDB:2R4R Chain:A ...(X-ray Resolution=3.40),Region:1-365(Identity=99%) PDB:2RH1 Chain:A (X-ray Resolution=2.40),Region:1-365(Identity...=99%) PDB:3D4S Chain:A (X-ray Resolution=2.80),Region:24-365(Identity=99%) PDB:2R4S Chain:A (X-ray Resolution=3.40), ...

Stable Ferroelectric Behavior of Nb-Modified Bi0.5K0.5TiO3-Bi(Mg0.5Ti0.5)O3 Lead-Free Relaxor Ferroelectric Ceramics

Science.gov (United States)

Zaman, Arif; Malik, Rizwan Ahmed; Maqbool, Adnan; Hussain, Ali; Ahmed, Tanveer; Song, Tae Kwon; Kim, Won-Jeong; Kim, Myong-Ho

2018-03-01

Crystal structure, dielectric, ferroelectric, piezoelectric, and electric field-induced strain properties of lead-free Nb-modified 0.96Bi0.5K0.5TiO3-0.04Bi(Mg0.5Ti0.5)O3 (BKT-BMT) piezoelectric ceramics were investigated. Crystal structure analysis showed a gradual phase transition from tetragonal to pseudocubic phase with increasing Nb content. The optimal piezoelectric property of small-signal d 33 was enhanced up to ˜ 68 pC/N with a lower coercive field ( E c) of ˜ 22 kV/cm and an improved remnant polarization ( P r) of ˜ 13 μC/cm2 for x = 0.020. A relaxor-like behavior with a frequency-dependent Curie temperature T m was observed, and a high T m around 320°C was obtained in the investigated system. This study suggests that the ferroelectric properties of BKT-BMT was significantly improved by means of Nb substitution. The possible shift of depolarization temperature T d toward high temperature T m may have triggered the spontaneous relaxor to ferroelectric phase transition with long-range ferroelectric order without any traces of a nonergodic relaxor state in contradiction with Bi0.5Na0.5TiO3-based systems. The possible enhancement in ferroelectric and piezoelectric properties near the critical composition x = 0.020 may be attributed to the increased anharmonicity of lattice vibrations which may facilitate the observed phase transition from a low-symmetry tetragonal to a high-symmetry cubic phase with a decrease in the lattice anisotropy of an undoped sample. This highly flexible (at a unit cell level) narrow compositional range triggers the enhancement of d 33 and P r values.

Maturation and germination of somatic embryos of Sorghum bicolor (L. Moench cultivar 'CIAP 132R-05'

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Silvio de J Martínez

2017-03-01

Full Text Available In sorghum [Sorghum bicolor (L. Moench], developed protocols for plant regeneration via somatic embryogenesis do not include maturation stage. The present work was carried out with the aim of achieving the maturation and germination of sorghum somatic embryos in cultivar 'CIAP 132R-05'. It were studied four concentrations of sucrose (30, 50, 70 and 90 g l-1, two of abscisic acid (0.25 and 0.5 μM and a control without this growth regulator. Germination initiation (days and number of somatic embryos with complete germination were evaluated in three periods (1 - 7, 8 - 14 and 15 - 21 days of culture. In addition, the effect of 6-BAP (8.9, 17.8 and 26.6 μM on somatic embryo germination was determined. The germination start time (days and after 21 days the number of somatic embryos with complete germination and plants with malformations were determined. The addition of 70 g l-1 sucrose in the culture medium without abscisic acid increased the germination of the somatic embryos to 37.2 plants per embryo group (0.5 g of fresh mass. The highest number of somatic embryos germinated was obtained with 17.78 μM 6-BAP in the germination culture medium. It was demonstrated the need of a maturation stage in the sorghum somatic embryogenesis to increase the germination percentage.   Keywords: somatic embryogenesis, sorghum, sucrose, 6-BAP

Annealing dependence of magnetic properties in nanostructured Sm0.5Y0.5Co5

International Nuclear Information System (INIS)

Elizalde-Galindo, J.T.; Hidalgo, J.L.; Botez, C.E.; Matutes-Aquino, J.A.

2008-01-01

Nanocrystalline Sm 0.5 Y 0.5 Co 5 powders with high coercivity H C and enhanced remanence M r were prepared by mechanical milling and subsequent annealing. Annealing temperatures T ranging from 973 to 1173 K, and times t ranging from 1 to 5 min were used. X-ray diffraction (XRD) and DC-magnetization measurements were carried out to study the microstructure and magnetic properties of these samples. XRD patterns demonstrate that the average grain size of the nanocrystalline powders depends on the annealing temperature T and time t: ranges from 11 nm (for T=973 K and t=1 min) to 93 nm (for T=1173 K and t=5 min). Magnetic measurements performed at room temperature indicate high coercivity values (H C >955 kA/m), and enhanced remanence (M r /M max >0.5) for all samples. A strong annealing-induced grain size dependence of these magnetic properties was found

A secondary fuel removal process: plasma processing

Energy Technology Data Exchange (ETDEWEB)

Min, J Y; Kim, Y S [Hanyang Univ., Seoul (Korea, Republic of); Bae, K K; Yang, M S [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

1997-07-01

Plasma etching process of UO{sub 2} by using fluorine containing gas plasma is studied as a secondary fuel removal process for DUPIC (Direct Use of PWR spent fuel Into Candu) process which is taken into consideration for potential future fuel cycle in Korea. CF{sub 4}/O{sub 2} gas mixture is chosen for reactant gas and the etching rates of UO{sub 2} by the gas plasma are investigated as functions of CF{sub 4}/O{sub 2} ratio, plasma power, substrate temperature, and plasma gas pressure. It is found that the optimum CF{sub 4}/O{sub 2} ratio is around 4:1 at all temperatures up to 400 deg C and the etching rate increases with increasing r.f. power and substrate temperature. Under 150W r.f. power the etching rate reaches 1100 monolayers/min at 400 deg C, which is equivalent to about 0.5mm/min. (author).

Comparison of primary and secondary 26S rRNA structures in two Tetrahymena species: evidence for a strong evolutionary and structural constraint in expansion segments

DEFF Research Database (Denmark)

Engberg, J; Nielsen, Henrik; Lenaers, G

1990-01-01

We have determined the nucleotide sequence of the 26S large subunit (LSU) rRNA genes for two Tetrahymena species, T. thermophila and T. pyriformis. The inferred rRNA sequences are presented in their most probable secondary structures based on compensatory mutations, energy, and conservation crite...

[Appraisal of occupational stress and strain in primary and secondary school teachers].

Science.gov (United States)

Wang, Z; Lan, Y; Li, J; Wang, M

2001-09-01

This study was conducted to assess occupational stress and strain in primary and secondary school teachers. A test of occupational stress and strain was carried out by using Occupational Stress Inventory Revised Edition (OSI-R) in 1460 primary and secondary school teachers (teacher group) and 319 mental workers in non-educational area (non-teacher group as control). The results showed the level of occupational stress in role overload and physical environment in the teacher group was significantly higher than that in the non-teacher group (P < 0.05). In teacher group the level of occupational stress and strain increased with age; the occupational stress and strain in male teachers were significantly higher than those in female teachers (P < 0.01); the occupational stress and strain in secondary school teachers were significantly higher than those in primary school teachers. These results indicate: to protect and promote primary and secondary school teacher's health, particularly male teachers' health, to mitigate their work pressure and to raise the quality of education are important tasks in the area of occupational health.

EFFECTS OF TWO METHODS OF INSTRUCTION ON STUDENTS’ CRITICAL RESPONSE TO PROSE LITERATURE TEXT IN ENGLISH IN SOME SECONDARY SCHOOLS IN BENIN CITY

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F. O. EZEOKOLI

2016-08-01

Full Text Available This study investigated the effects of two methods of instruction on secondary school students’ critical response to Prose Literature text. The study adopted a pretest, posttest, control group quasi experimental design. The participants in the study were 84 Senior Secondary II students of Literature-in-English purposively selected from four Schools in Ikpoba-Okha Local Government Area of Edo State. Two intact classes were randomly assigned to each of the treatment and control groups. Three hypotheses were tested at 0.05 alpha level. The instruments used were: Critical Response to Prose Literature Test (r = .75, Questionnaire on Home Background of Students (r = .82, and Critical Response to Prose Literature Test Marking Guide. Data obtained were subjected to Analysis of Covariance and graph. The results showed significant main effect of treatment on students’ critical response to Prose Literature (F (1, 77 = 44.731; p < .05. Students exposed to Engagement Strategies Method performed better than those exposed to the Conventional Method of instruction. Further, home background of students had no significant effect on students’ critical response to Prose Literature text (F (2, 77 = 4.902; p < .05. There was significant interaction effect of treatment and home background of students on students’ critical response to Prose Literature text (F (2, 77 = 3.508; p < .05. It was concluded that Engagement Strategies Method is effective in promoting students’ critical response to Prose Literature text. Teachers of Literature-in-English should employ Engagement Strategies Method in teaching Prose Literature to students in Senior Secondary Schools.

Integral Combinations of Heavisides

Czech Academy of Sciences Publication Activity Database

Kainen, P.C.; Kůrková, Věra; Vogt, A.

2010-01-01

Roč. 283, č. 6 (2010), s. 854-878 ISSN 0025-584X R&D Projects: GA ČR GA201/05/0557; GA ČR GA201/08/1744 Institutional research plan: CEZ:AV0Z10300504 Keywords : feedforward neural network * perceptron * heaviside function * plane wave * integral formula * radon transform * Green’s function for iterated Laplacians * order of vanishing * function of controlled decay Subject RIV: BA - General Mathematics Impact factor: 0.653, year: 2010

Noise in secondary electron emission: the low yield case

Czech Academy of Sciences Publication Activity Database

Frank, Luděk

2005-01-01

Roč. 54, č. 4 (2005), s. 361-365 ISSN 0022-0744 R&D Projects: GA AV ČR(CZ) IAA1065304 Keywords : secondary electrons * noise * SEM image noise * secondary emission noise * statistics of secondary electrons * non-Poisson factor Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 0.720, year: 2005

NIRSpec optics development: final report

Science.gov (United States)

Geyl, R.; Ruch, E.; Vayssade, H.; Leplan, H.; Rodolfo, J.

2017-11-01

As shown and discussed on a Sagem poster presented at the ICSO 2010 conference [1], scientific or commercial earth observation space instruments are more and more taking advantage of the remarkable properties of Silicon Carbide in term of hardness, stiffness and thermal stability combined with a reasonable density which are indeed of primary importance for all space applications. Sagem-REOSC High Performance Optics Unit works on the polishing, coating and integration technologies of SiC mirrors since more than ten year through various successful space programs for various customers: INSAT 3D scan mirror, ROCSAT II and SPIRALE main telescopes, GAIA large primary mirrors and Auto-collimation flats, …). This paper aims to provide to the international space community an exhaustive vision of the work performed by Sagem-REOSC on the polishing, coating and integration of the three Three Mirror Anastigmats of the NIRSpec spectrographic instrument which is the main ESA contribution to the JWST.

Global and local structural variations near the antiferroelectric regime in Na{sub 0.5}Bi{sub 0.5}TiO{sub 3}

Energy Technology Data Exchange (ETDEWEB)

Thangavelu, Karthik [Advanced Functional Materials Laboratory, Department of Physics, Indian Institute of Technology Hyderabad, ODF-Campus-502205 (India); Department of Materials Science and Metallurgical Engineering, Indian Institute of Technology Hyderabad, ODF-Campus-502205 (India); Rayaprol, S. [UGC-DAE CSR Mumbai Centre, BARC Campus, Mumbai - 400085 (India); Siruguri, V. [Solid State Physics Division, Bhabha Atomic Research Centre, Mumbai - 400085 (India); Sastry, P. U.; Asthana, Saket, E-mail: asthanas@iith.ac.in

2015-06-24

Rietveld refinement of neutron and x-ray diffraction data of Na{sub 0.5}Bi{sub 0.5}TiO{sub 3} shows R3c phase stabilization at room temperature. The intermediate antiferroelectric region between 180°C to 280°C exhibits phase coexistence i.e R3c + Pnma, along with decrease in octahedral tilt angle and increase in unit cell volume. The local structural changes observed from Raman scattering in the A-O, Ti-O and TiO{sub 6} phonon modes favor the global structural variation. A possible antiparallel cation displacement due to Pnma phase formation leads to the origin of antiferroelectric ordering in Na{sub 0.5}Bi{sub 0.5}TiO{sub 3}.

SECONDARY ECLIPSE PHOTOMETRY OF THE EXOPLANET WASP-5b WITH WARM SPITZER

Energy Technology Data Exchange (ETDEWEB)

Baskin, Nathaniel J.; Knutson, Heather A.; Desert, Jean-Michel [Division of Geological and Planetary Sciences, California Institute of Technology, Pasadena, CA 91125 (United States); Burrows, Adam [Department of Astrophysical Sciences, Princeton University, Princeton, NJ 05844 (United States); Fortney, Jonathan J.; Laughlin, Gregory [Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA 95064 (United States); Lewis, Nikole K. [Department of Earth, Atmospheric and Planetary Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139 (United States); Agol, Eric [Department of Astronomy, University of Washington, Box 351580, Seattle, WA 98195 (United States); Charbonneau, David [Harvard-Smithsonian Center for Astrophysics, Cambridge, MA 02138 (United States); Cowan, Nicolas B. [Center for Interdisciplinary Exploration and Research in Astrophysics, Northwestern University, Evanston, IL 60208 (United States); Deming, Drake [Department of Astronomy, University of Maryland, College Park, MD 20742 (United States); Langton, Jonathan [Department of Physics, Principia College, Elsah, IL 62028 (United States); Showman, Adam P. [Lunar and Planetary Laboratory, University of Arizona, Tucson, AZ 85721 (United States)

2013-08-20

We present secondary eclipse photometry of the extrasolar planet WASP-5b taken in the 3.6 and 4.5 {mu}m bands with the Spitzer Space Telescope's Infrared Array Camera as part of the extended warm mission. By estimating the depth of the secondary eclipse in these two bands we can place constraints on the planet's atmospheric pressure-temperature profile and chemistry. We measure secondary eclipse depths of 0.197% {+-} 0.028% and 0.237% {+-} 0.024% in the 3.6 {mu}m and 4.5 {mu}m bands, respectively. For the case of a solar-composition atmosphere and chemistry in local thermal equilibrium, our observations are best matched by models showing a hot dayside and, depending on our choice of model, a weak thermal inversion or no inversion at all. We measure a mean offset from the predicted center of eclipse of 3.7 {+-} 1.8 minutes, corresponding to ecos {omega} = 0.0025 {+-} 0.0012 and consistent with a circular orbit. We conclude that the planet's orbit is unlikely to have been perturbed by interactions with another body in the system as claimed by Fukui et al.

Diseño de una formulación de ketotifeno 0,025 % colirio

Directory of Open Access Journals (Sweden)

Yenilen Troche Concepción

Full Text Available El colirio de ketotifeno se indica para aliviar los signos y síntomas de las conjuntivitis alérgicas, por ser este un potente antihistamínico H1 que muestra cierta capacidad para inhibir la liberación de histamina y otros mediadores en mastocitos. El objetivo del presente trabajo consistió en realizar el desarrollo tecnológico del colirio de ketotifeno 0,025 %, de producción nacional teniendo en cuenta que es un medicamento muy utilizado en la "Operación Milagro", en la cual participa la República de Cuba, para lo que se hace un diseño y los estudios de preformulación. Se estudió además, las especificaciones de calidad de la formulación seleccionada, la estabilidad del producto y el tiempo de vigencia de este. Se realizó el estudio de estabilidad acelerado y por vida de estante, para lo cual se emplearon 3 lotes del producto a escala piloto. El colirio resultó estable física, química y microbiológicamente envasado en frascos de polietileno de baja densidad, por espacio de 12 meses a temperatura ambiente

Bupivacaína com excesso enantiomérico (S75-R25 a 0,5%, bupivacaína racêmica a 0,5% e lidocaína a 2% no bloqueio do nervo facial pela técnica de O'Brien: estudo comparativo Bupivacaína con exceso enantiomérico (S75-R25 a 0,5%, bupivacaína racémica a 0,5% y lidocaína a 2% en el bloqueo del nervio facial por la técnica de O'Brien: estudio comparativo 0.5% enantiomeric excess bupivacaine (S75-R25, 0.5% racemic bupivacaine, and 2%lidocaine for facial nerve block by the O'Brien technique: a comparative study

Directory of Open Access Journals (Sweden)

Luis Henrique Cangiani

2007-04-01

Full Text Available JUSTIFICATIVA E OBJETIVOS: Mistura de enantiômeros da bupivacaína em diferentes formulações, S75-R25 ou S90-R10, foi proposta objetivando menor cardiotoxicidade e bloqueio motor satisfatório. O objetivo deste estudo foi comparar o tempo de instalação e o grau de bloqueio motor utilizando a bupivacaína com excesso enantiomérico de 50% (S75-R25 a 0,5%, a bupivacaína racêmica a 0,5% e a lidocaína a 2% no bloqueio do nervo facial pela técnica de O'Brien. MÉTODO: Participaram do estudo 45 pacientes, com idade acima de 60 anos, programados para tratamento cirúrgico de catarata sob bloqueio retrobulbar, precedido pela acinesia de O'Brien. Os pacientes foram divididos de forma aleatória em três grupos de 15, de acordo com a solução anestésica empregada para o bloqueio do nervo facial: Grupo L (Lidocaína, Grupo B (Bupivacaína e Grupo M (S75-R25. Foram injetados 3 mL da solução. Foram verificados o tempo de instalação e o grau do bloqueio motor (Graus 1, 2 e 3 aos 15 segundos após a injeção e, sucessivamente, a cada 15 segundos até completar 180 segundos. RESULTADOS: As manifestações iniciais do bloqueio foram mais rápidas (15s no Grupo L do que nos Grupos B e M. Não houve diferença entre os Grupos B e M. Todos os pacientes do Grupo L apresentaram bloqueio motor Grau 3 em até 60 segundos, tempo menor do que aqueles observados nos Grupos B e M (120 e 135, respectivamente. Os grupos B e M tiveram comportamento semelhante ao longo do estudo, não havendo diferença estatística entre eles. Aos 180 segundos o bloqueio motor Grau 3 foi semelhante nos três grupos. CONCLUSÕES: A instalação do bloqueio motor e o grau máximo de bloqueio foram obtidos com mais rapidez com a lidocaína a 2%. O mesmo grau foi atingido pela bupivacaína racêmica e pela S75-R25, porém em tempo maior. Esses dois anestésicos apresentaram o mesmo comportamento com relação à latência e ao grau máximo do bloqueio motor, e ao término de 180

Post-Mortem Analysis after High-Power Operation of the TD24_R05 Tested in Xbox_1

CERN Document Server

Degiovanni, Alberto; Mouriz Irazabal, Nerea; Aicheler, Markus

2016-01-01

The CLIC prototype structure TD24_R05 has been high power tested in Xbox_1 in 2013. This report summarizes all examinations conducted after the high power test including bead-pull measurements, structure cutting, metrology and SEM observations. A synthesis of the various results is then made. The structure developed a hot cell progressively during operation and detuning was observed after the test was complete. The post mortem examination clearly showed a developed standing wave pattern which was explained by the physical deformation of one of the coupler iris. An elevated breakdown count through SEM imaging in the suspected hot cell however could not be confirmed. Neither any particular feature offering an explanation for the observed longitudinal breakdown distribution could be detected.

Calibration of the NPL secondary standard radionuclide calibrator for the new 10R Schott, Type 1+ vials

International Nuclear Information System (INIS)

Baker, M.

2005-01-01

For many years, P6 vials have been used for the distribution of a wide range of diagnostic and therapeutic radioactive solutions. The activity measurements were performed in this geometry and, in time, the UK calibration system for nuclear medicine was based on this container as a standard. However, one major supplier of radiopharmaceuticals has replaced the P6 vial with the 10R Type 1+ Schott vial. As the dimensions of the new vial are different from those of the P6 vial and the responses of radionuclide calibrators are known to be container dependent, the need for re-calibration became apparent. Preliminary measurements made on some typical radionuclide calibrators for 125 I solution indicated a difference in response of about 10% between the two vials. The master ionisation chamber of the NPL secondary standard radionuclide calibrator has been re-calibrated and new calibration factors and volume correction factors for 10R Schott vials have been derived for the relevant medical radionuclides. The standard holder was also modified to accommodate the new larger vial. The complete list of factors and the method used to determine them is presented in this paper. The availability of these new factors will improve the quality of activity measurements in nuclear medicine, as calibration services can now be provided by NPL for the new container. These factors can also be employed for all commercial NPL secondary standard radionuclide calibrators (now known as the NPL-CRC and previously as the 671 or ISOCAL IV)

Anestesia peridural para cesariana: estudo comparativo entre Bupivacaína Racêmica (S50-R50 e Bupivacaína com excesso enantiomérico de 50% (S75-R25 a 0,5% associadas ao Sufentanil Anestesia epidural para cesárea: estudio comparativo entre Bupivacaína Racémica (S50-R50 y Bupivacaína con exceso enantiomérico de 50% (S75-R25 a 0,5% asociadas al Sufentanil Epidural block for cesarean section: a comparative study between 0.5% racemic Bupivacaine (S50-R50 and 0.5% enantiomeric excess Bupivacaine (S75-R25 associated with Sufentanil

Directory of Open Access Journals (Sweden)

Angélica de Fátima de Assunção Braga

2009-06-01

Full Text Available JUSTIFICATIVA E OBJETIVOS: A bupivacaína racêmica a 0,5% associada a opioides por via peridural constitui técnica anestésica utilizada em cesariana, entretanto sua toxicidade é questionada. A bupivacaína com excesso enantiomérico de 50% apresenta menor cárdio e neurotoxicidade. Avaliou-se a eficácia da bupivacaína racêmica e da bupivacaína com excesso enantiomérico de 50% a 0,5%, associadas ao sufentanil, por via peridural, em gestantes submetidas à cesariana. MÉTODO: Cinquenta gestantes a termo, submetidas à cesariana eletiva, sob bloqueio peridural, distribuídas em dois grupos, de acordo com o anestésico local empregado: Grupo I - bupivacaína racêmica a 0,5% com vasoconstritor; Grupo II - bupivacaína com excesso enantiomérico de 50% (S75-R25 a 0,5% com vasoconstritor. Nos dois grupos o anestésico local (100 mg foi associado ao sufentanil (20 µg e o volume total empregado da solução foi de 24 mL. Avaliaram-se: latência do bloqueio sensitivo; nível máximo do bloqueio sensitivo; grau do bloqueio motor; tempo para regressão do bloqueio motor; duração da analgesia; efeitos colaterais maternos e repercussões neonatais. RESULTADOS: A latência, o nível máximo do bloqueio sensitivo, o grau do bloqueio motor e a duração da analgesia foram semelhantes nos dois grupos; o tempo para regressão do bloqueio motor foi significativamente menor no Grupo II. Os efeitos colaterais ocorreram com frequência semelhante em ambos os grupos. Ausência de alterações cardiocirculatórias maternas e repercussões neonatais. CONCLUSÕES: A bupivacaína racêmica e a bupivacaína com excesso enantiomérico de 50%, por via peridural, proporcionam anestesia adequada para realização de cesariana. A bupivacaína com excesso enantiomérico de 50% constitui alternativa promissora para esse tipo de procedimento, por apresentar menor tempo para regressão do bloqueio motor, desejável na paciente obstétrica.JUSTIFICATIVA Y OBJETIVOS: La

3x2 Classroom Goal Structures, Motivational Regulations, Self-Concept, and Affectivity in Secondary School.

Science.gov (United States)

Méndez-Giménez, Antonio; Cecchini-Estrada, José-Antonio; Fernández-Río, Javier; Prieto Saborit, José Antonio; Méndez-Alonso, David

2017-09-20

The main objective was to analyze relationships and predictive patterns between 3x2 classroom goal structures (CGS), and motivational regulations, dimensions of self-concept, and affectivity in the context of secondary education. A sample of 1,347 secondary school students (56.6% young men, 43.4% young women) from 10 different provinces of Spain agreed to participate (M age = 13.43, SD = 1.05). Hierarchical regression analyses indicated the self-approach CGS was the most adaptive within the spectrum of self-determination, followed by the task-approach CGS. The other-approach CGS had an ambivalent influence on motivation. Task-approach and self-approach CGS predicted academic self-concept (p approach CGS (negatively) predicted family self-concept (p approach and other-approach CGS's (p approach-oriented CGS's (p approach (positively) and self-approach (negatively) CGS (p < .001; p < .05, respectively; R 2 = .028). These results expand the 3x2 achievement goal framework to include environmental factors, and reiterate that teachers should focus on raising levels of self- and task-based goals for students in their classes.

H2S interaction with Cu(100)-(2 √2 × √2 )R45°-O: Formation of a metastable ‖05 52sulfur surface reconstruction

DEFF Research Database (Denmark)

Colaianni, M. L.; Syhler, P.; Chorkendorff, Ib

1995-01-01

This paper utilizes scanning tunneling microscopy, low-energy electron diffraction, Auger-electron spectroscopy, and temperature-programmed desorption to examine a metastable \\(52)(05)\\-S structure which forms after the interface reaction of H2S with a Cu(100)-(2 root (2) over bar X root (2) over....... Heating the \\(52)(05)\\-S surface to temperatures above 600 K converts this structure to the thermally stable Cu(100)rootX root)R14 degrees-S (i.e., \\((1) over bar 4)(41)\\-S overlayer. A model for the metastable \\(52)(05)\\-S reconstruction is proposed....

Thermal Behaviour of Sm0.5 R 0.5FeO3 (R = Pr, Nd) Probed by High-Resolution X-ray Synchrotron Powder Diffraction.

Science.gov (United States)

Pavlovska, Olena; Vasylechko, Leonid; Buryy, Oleh

2016-12-01

Mixed ferrites Sm0.5Pr0.5FeO3 and Sm0.5Nd0.5FeO3 with orthorhombic perovskite structure isotypic with GdFeO3 were synthesized by solid-state reaction technique in air at 1473 K. Structural parameters obtained at room temperature prove a formation of continuous solid solutions in the SmFeO3-PrFeO3 and SmFeO3-NdFeO3 pseudo-binary systems. Sm0.5Pr0.5FeO3 and Sm0.5Nd0.5FeO3 show strongly anisotropic nonlinear thermal expansion: thermal expansion in the b direction is twice lower than in the a and c directions. The average linear thermal expansion coefficients of Sm0.5Pr0.5FeO3 and Sm0.5Nd0.5FeO3 in the temperature range of 298-1173 K are in the limits of (9.0-11.1) × 10(-6) K(-1), which is close to the values reported for the parent RFeO3 compounds. Subtle anomalies in the lattice expansion of Sm0.5Pr0.5FeO3 and Sm0.5Nd0.5FeO3 detected at 650-750 K reflect magnetoelastic coupling at the magnetic ordering temperature T N.

Crystal structure and optical absorption spectra of Ga0.5Fe0.5InS3 and Ga0.5Fe0.25In1.25S3 crystals

International Nuclear Information System (INIS)

Gusejnov, G.G.; Musaeva, N.N.; Kyazumov, M.G.; Asadova, I.B.; Aliev, O.M.

2003-01-01

Single crystals of Ga 0.5 Fe 0.5 InS 3 are grown by the method of chemical gas-transport reactions and those of Ga 0.5 Fe 0.25 In 1.25 S 3 - by Bridgman method. X-ray diffraction studies reveal that they crystallize in trigonal and rhombohedral systems with lattice parameters of a = 3.796 x 2 A, c = 12.210 A, P3m1; a = 3.786 x 2 A, c = 36.606 A, R3m, respectively. An optical absorption edge in a wide range of photon energy and an energy gap width are determined: E g = 1.885 eV for Ga 0.5 Fe 0.5 InS 3 and E g 1.843 eV for Ga 0.5 Fe 0.25 In 1.25 S 3 [ru

Electrochemical behaviour of copper in N,N-dimethylformamide + 0.5 M potassium perchlorate solution

Directory of Open Access Journals (Sweden)

S. MENTUS

2000-09-01

Full Text Available The electrochemical deposition and dissolution of copper in 0.0025 M CuSO4 + N,N-dimethylformamide + 0.5 M KClO4 solution was examined by the rotating disc and potentiodynamic methods. Both platinum and copper were used as working electrodes. A wide polarization range –1 to +2 V vs. SCE, and several temperatures between 25 and 55°C were encompased. The Cu/electrolyte interface was found to be permanently out of equilibrium, as a consequence of the development of a passivating layer. In accordance with the classic theory of a copper electrode in acidified aqueous solutions, the cathodic and anodic Tafel lines of metallic copper define a unique value of the exchange current density, however, their slopes do not correspond to the classic theory.

Flow Accelerated Erosion-Corrosion (FAC) considerations for secondary side piping in the AP1000{sup R} nuclear power plant design

Energy Technology Data Exchange (ETDEWEB)

Vanderhoff, J. F.; Rao, G. V. [Westinghouse Electric Company LLC, 1000 Westinghouse Drive, Cranberry Township, PA 16066 (United States); Stein, A. [Shaw Power Nuclear, 1000 Technology Center Drive, Stoughton, MA 02072 (United States)

2012-07-01

The issue of Flow Accelerated Erosion-Corrosion (FAC) in power plant piping is a known phenomenon that has resulted in material replacements and plant accidents in operating power plants. Therefore, it is important for FAC resistance to be considered in the design of new nuclear power plants. This paper describes the design considerations related to FAC that were used to develop a safe and robust AP1000{sup R} plant secondary side piping design. The primary FAC influencing factors include: - Fluid Temperature - Pipe Geometry/layout - Fluid Chemistry - Fluid Velocity - Pipe Material Composition - Moisture Content (in steam lines) Due to the unknowns related to the relative impact of the influencing factors and the complexities of the interactions between these factors, it is difficult to accurately predict the expected wear rate in a given piping segment in a new plant. This paper provides: - a description of FAC and the factors that influence the FAC degradation rate, - an assessment of the level of FAC resistance of AP1000{sup R} secondary side system piping, - an explanation of options to increase FAC resistance and associated benefits/cost, - discussion of development of a tool for predicting FAC degradation rate in new nuclear power plants. (authors)

The development of PISA reading competence in secondary education

Directory of Open Access Journals (Sweden)

Jovanović Vitomir

2016-01-01

Full Text Available The aim of the paper is to provide a contribution to answering the question about the most important predictors of progress in reading competence achieved by students after two years of secondary education, as well as whether the set of predictors of progress is different from the set of predictors of achievement in reading literacy test and school achievement measured via school grades. The students from the sample for the PISA 2009 study conducted in Serbia were tested again after two years by the PISA reading literacy test, quasi longitudinally, measuring achievement correlates at another time point. The realised sample included 20 secondary schools and 446 students. We selected fourteen predictors that, according to the studies so far, proved to have highest correlations with school achievement. The results have shown that the predictors explain only 13% of variance of the progress in reading literacy test (R=.36; R2=.13; F =12.97; p<.05 although they explain 49% of variance of achievement at it (R=.70; R2 197,18 =.49; F257,18 =12.97; p<.001. This opens up the issue of the importance of early learning for progress in reading competence. In both the first and the second analysis, the strongest predictor was the autonomous form of extrinsic motivation which, according to the self-determination theory, speaks about the importance of learning for future life and career. A somewhat different set of used predictors predicted school achievement measured via school grades. Using metacognitive strategies is not an important predictor of school achievement while it is the predictor of achievement in the reading literacy test. Together with the findings pointing towards the lower than expected correlation between achievement in reading literacy and school achievement (r=.39; p<0.001 and generally low progress of Serbia at this test compared to the estimated progress of the OECD countries, these results give grounds for the conclusion that our

Iridium-Catalyzed Condensation of Primary Amines To Form Secondary Amines

DEFF Research Database (Denmark)

Lorentz-Petersen, Linda Luise Reeh; Jensen, Paw; Madsen, Robert

2009-01-01

Symmetric secondary amines are readily obtained by heating a neat primary amine with 0.5 mol% of bis(dichloro[eta(5)-pentamethylcyclopentadienyl]iridium). The products are isolated by direct distillation in good yields.......Symmetric secondary amines are readily obtained by heating a neat primary amine with 0.5 mol% of bis(dichloro[eta(5)-pentamethylcyclopentadienyl]iridium). The products are isolated by direct distillation in good yields....

Effect of cerium additive and secondary phase analysis on Ag0.5Bi0 ...

Indian Academy of Sciences (India)

Technical University of Madrid (UPM), Madrid 28012, Spain. MS received 27 ... XRD analysis showed the presence of pyrochlore structure and secondary phase when more .... The present work reports the effect of incorporation of cerium in ...

Room-temperature ferromagnetism in Fe-based perovskite solid solution in lead-free ferroelectric Bi0.5Na0.5TiO3 materials

Science.gov (United States)

Hung, Nguyen The; Bac, Luong Huu; Trung, Nguyen Ngoc; Hoang, Nguyen The; Van Vinh, Pham; Dung, Dang Duc

2018-04-01

The integration of ferromagnetism in lead-free ferroelectric materials is important to fabricate smart materials for electronic devices. In this work, (1 - x)Bi0.5Na0.5TiO3 + xMgFeO3-δ materials (x = 0-9 mol%) were prepared through sol-gel method. X-ray diffraction characterization indicated that MgFeO3-δ materials existed as a well solid solution in lead-free ferroelectric Bi0.5Na0.5TiO3 materials. The rhombohedral structure of Bi0.5Na0.5TiO3 materials was distorted due to the random distribution of Mg and Fe cations into the host lattice. The reduced optical band gap and the induced room-temperature ferromagnetism were due to the spin splitting of transition metal substitution at the B-site of perovskite Bi0.5Na0.5TiO3 and the modification by A-site co-substitution. This work elucidates the role of secondary phase as solid solution in Bi0.5Na0.5TiO3 material for development of lead-free multiferroelectric materials.

Validation of analytical method to quality control and the stability study of 0.025 % eyedrops Ketotiphen

International Nuclear Information System (INIS)

Troche Concepcion, Yenilen; Romero Diaz, Jacqueline Aylema; Garcia Penna, Caridad M

2010-01-01

The Ketotiphen eyedrop is prescribed to relief the signs and symptoms of allergic conjunctivitis due to its potent H 1a ntihistaminic effect showing some ability to inhibit the histamine release and other mediators in cases of mastocytosis. The aim of present paper was to develop and validate an analytical method for the high-performance liquid chromatography, to quality control and the stability studies of 0.025 % eyedrop Ketotiphen. Method was based on active principle separation by means of a Lichrosorb RP-18 (5 μm) (250 x 4 mm), with UV detection to 296 nm using a mobile phase including a non-gasified mixture of methanol:buffer-phosphate (75:25; pH 8.5) adding 1 mL of Isopropanol by each 1 000 mL of the previous mixture at a 1.2 mL/min flow velocity. The analytical method was linear, accurate, specific and exact during the study concentrations

A randomized, double-blind, multicenter, parallel group study to compare relative efficacies of the topical gels 3% erythromycin/5% benzoyl peroxide and 0.025% tretinoin/erythromycin 4% in the treatment of moderate acne vulgaris of the face.

Science.gov (United States)

Gupta, Aditya K; Lynde, Charles W; Kunynetz, Rod A W; Amin, Smita; Choi, Ken; Goldstein, Eric

2003-01-01

Combination treatments for acne vulgaris, such as Benzamycin (3% erythromycin/5% benzoyl peroxide) and Stievamycin (0.025% tretinoin/erythromycin 4%), reduce bacterial growth, which contributes to the inflammatory lesions typical of adolescent acne, and also decrease the epidermal cell compaction which may form the characteristic noninflammatory comedone. Both agents contain erythromycin to reduce the growth of Propionibacterium acnes in skin. Benzoyl peroxide has antibiotic activity as well as anticomedogenic properties. Tretinoin may increase the turnover of epidermal cells and loosen the cells compacted to form comedones. A combination preparation containing the two antibiotics may reduce the development of resistance; the combination preparation containing tretinoin and erythromycin will have an antibiotic effect as well as acting on differentiation. This multicenter, randomized, double-blind, parallel group study compared the effectiveness of 3% erythromycin/5% benzoyl peroxide and 0.025% tretinoin/erythromycin 4%, each applied twice daily in patients with moderate acne vulgaris. Overall physician and patient ratings of severity of acne symptoms were performed at baseline and at weeks 2, 4, 8, and 12. At baseline the two treatment groups had similar disease severity. The number of papules, pustules, and comedones was reduced in both treatment groups at week 12, and the reductions were not significantly different between the two comparators. Global physician rating of improvement was significantly higher in the 3% erythromycin/5% benzoyl peroxide group compared with the 0.025% tretinoin/erythromycin 4% group; however, there was no significant difference in global patient ratings between the two treatment groups. An aggregate score was produced, for both physician rating and patient rating, by adding up individual symptom severity ratings. Compared with 0.025% tretinoin/erythromycin 4%, 3% erythromycin/5% benzoyl peroxide provided significantly greater reduction

Influence of Secondary Hyperparathyroidism Induced by Low Dietary Calcium, Vitamin D Deficiency, and Renal Failure on Circulating Rat PTH Molecular Forms.

Science.gov (United States)

D'Amour, Pierre; Rousseau, Louise; Hornyak, Stephen; Yang, Zan; Cantor, Tom

2011-01-01

Rats(r) with secondary hyperparathyroidism were studied to define the relationship between vitamin D metabolites and rPTH levels measured by 3 different rat ELISAs. Controls and renal failure (RF) rats were on a normal diet, while 2 groups on a low-calcium (-Ca) or a vitamin D-deficient (-D) diet. RF was induced surgically. Mild RF rats had normal calcium and 25(OH)D but reduced 1,25(OH)(2)D levels (P < .001) with a 2.5-fold increased in rPTH (P < .001). Severe RF rats and those on a -Ca or -D diet had reduced calcium (P < .01) and 25(OH)D levels (P < .05), with rPTH increased by 2 (-Ca diet; P < .05), 4 (-D diet; P < .001), and 20-folds (RF; P < .001) while 1,25(OH)(2)D was high (-Ca diet: P < .001) or low (-D diet, RF: P < .001). 25(OH)D and 1,25(OH)(2)D were positively and negatively related on the -Ca and -D diets, respectively. rPTH molecular forms behaved as expected in RF and on -Ca diet, but not on -D diet with more C-rPTH fragments when less were expected. This may be related to the short-time course of this study compared to prior studies.

Synthesis and piezoelectric properties of (1 - x)Bi0.5(Na0.8K0.2)0.5TiO3-xSr2ZrTiO6 ceramics

Science.gov (United States)

Onishi, Ryo; Ogawa, Hirotaka; Iida, Daiki; Kan, Akinori

2017-10-01

The effects of Sr2ZrTiO6 (SZT) addition on the piezoelectric properties of (1 - x)Bi0.5(Na0.8K0.2)0.5TiO3 (BNKT)-xSZT ceramics were characterized in this study. The X-ray powder diffraction (XRPD) profiles and Raman spectra of the ceramics in the composition range of 0-0.02 implies the presence of morphotropic phase boundary (MPB) which consists of the rhombohedral and tetragonal phases. Moreover, the temperature dependence of dielectric loss indicated a presence of the ferroelectric-relaxor transition temperature (T F-R) of around 75 °C for x = 0.005 and the temperature dependence shifted to a lower temperature at x = 0.01. The temperature dependence of the P-E hysteresis loop of the ceramics at the compositions of x = 0.005-0.02 showed pinched hysteresis loops above T F-R. Regarding the piezoelectric constant (d 33), it was increased by SZT addition in the MPB region (x = 0-0.01) and the highest d 33 of 202 pC/N was obtained at the composition of x = 0.0025. The S-E unipolar loop was also evaluated, the strain of the ceramic increased up to x = 0.02; and the highest d33* = 436 pm/V was obtained at the composition of x = 0.02.

Remifentanil for the insertion and removal of long-term central venous access during monitored anesthesia care.

LENUS (Irish Health Repository)

Burlacu, Crina L

2012-02-01

STUDY OBJECTIVE: To determine the analgesic efficacy of three different rates of remifentanil infusion in patients undergoing insertion or removal of long-term central venous access devices during monitored anesthesia care and local anesthetic field infiltration. DESIGN: Double-blinded, randomized, controlled study. SETTING: Operating theatre of an University hospital. PATIENTS: 44 unpremedicated, ASA physical status 1 and 2 patients, aged 18-65 years, undergoing insertion or removal of a Port-a-Cath or Hickman catheter. INTERVENTIONS: Patients sedated with a propofol target-controlled infusion were randomly allocated to three groups: Group R25 (n = 14), Group R50 (n = 15), and Group R75 (n = 15), to receive remifentanil 0.025, 0.05, and 0.075 mug\\/kg\\/min, respectively. Rescue remifentanil 0.5 mug\\/kg was administered for pain scores > 3. The remifentanil infusion rate was maintained constant unless respiratory and\\/or cardiovascular unwanted events occurred, whereupon the rate was adjusted in 0.01 mug\\/kg\\/min decrements as necessary. MEASUREMENTS: Pain scores (primary outcome), sedation, and movement scores (secondary outcomes) were assessed during local anesthetic infiltration of the anterior chest wall and 5 other procedural steps. MAIN RESULTS: All infusion rates had equal analgesic efficacy, as shown by comparable pain scores, number of rescue boluses, and number of patients requiring rescue analgesia. Excessive sedation was associated with the highest remifentanil rate such that Group R75 patients were significantly more sedated than Groups R25 or R50 at selective procedural steps (P < 0.05). More Group R75 patients (6\\/15) required remifentanil rate reduction than did patients from Group R50 (1\\/15) or Group R25 (0\\/14), P < 0.01, most commonly because of respiratory depression. CONCLUSIONS: For the insertion or removal of long-term central venous access devices, all three remifentanil infusion rates proved to be equally analgesic

Illumina microRNA profiles reveal the involvement of miR397a in Citrus adaptation to long-term boron toxicity via modulating secondary cell-wall biosynthesis.

Science.gov (United States)

Huang, Jing-Hao; Qi, Yi-Ping; Wen, Shou-Xing; Guo, Peng; Chen, Xiao-Min; Chen, Li-Song

2016-03-10

The mechanisms underlying tolerance to B-toxicity in plants are still controversial. Our previous studies indicated that B-toxicity is mainly limited to leaves in Citrus and that alternations of cell-wall structure in vascular bundles are involved in tolerance to B-toxicity. Here, miRNAs and their expression patterns were first identified in B-treated Citrus sinensis (tolerant) and C. grandis (intolerant) leaves via high-throughput sequencing. Candidate miRNAs were then verified with molecular and anatomical approaches. The results showed that 51 miRNAs in C. grandis and 20 miRNAs in C. sinensis were differentially expressed after B-toxic treatment. MiR395a and miR397a were the most significantly up-regulated miRNAs in B-toxic C. grandis leaves, but both were down-regulated in B-toxic C. sinensis leaves. Four auxin response factor genes and two laccase (LAC) genes were confirmed through 5'-RACE to be real targets of miR160a and miR397a, respectively. Up-regulation of LAC4 resulted in secondary deposition of cell-wall polysaccharides in vessel elements of C. sinensis, whereas down-regulation of both LAC17 and LAC4, led to poorly developed vessel elements in C. grandis. Our findings demonstrated that miR397a plays a pivotal role in woody Citrus tolerance to B-toxicity by targeting LAC17 and LAC4, both of which are responsible for secondary cell-wall synthesis.

Comparison of endotoxin levels found in primary and secondary endodontic infections.

Science.gov (United States)

Gomes, Brenda P F A; Endo, Marcos S; Martinho, Frederico C

2012-08-01

This clinical study was conducted to compare the levels of endotoxins (lipopolysaccharides [LPSs]) found in primary and secondary endodontic infections with apical periodontitis by correlating LPS contents with clinical/radiographic findings. In addition, the presence of target gram-negative anaerobic bacteria was also investigated. Samples were taken from 15 root canals with primary infections and 15 with secondary infections by using paper points. The limulus amebocyte lysate assay was used to quantify endotoxins, and the polymerase chain reaction technique (16S rDNA) was used for bacterial investigation. Endotoxins were detected in 100% of the root canal samples collected from primary (15/15) and secondary (15/15) infections with median values of 7.49 EU/mL and 3.96 EU/mL, respectively (P asymptomatic teeth with primary infections (P 3 mm) (P < .05). Prevotella nigrescens (10/15, 4/15), Fusobacterium nucleatum (5/15, 1/15), Treponema denticola (3/15, 1/15), and Treponema socranskii (5/15, 1/15) were detected in teeth with primary and secondary infections, respectively. P. endodontalis was present only in teeth with primary infections (5/15). Teeth with primary endodontic infections had higher contents of endotoxins and a more complex gram-negative bacterial community than teeth with secondary infections. Moreover, the levels of endotoxins were related to the severity of bone destruction in periapical tissues as well as the development of clinical features in teeth with primary infections. Copyright © 2012 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

Crystal structure and optical absorption spectra of Ga{sub 0.5}Fe{sub 0.5}InS{sub 3} and Ga{sub 0.5}Fe{sub 0.25}In{sub 1.25}S{sub 3} crystals; Struktura i opticheskoe pogloshchenie kristallov Ga{sub 0.5}Fe{sub 0.5}InS{sub 3} i Ga{sub 0.5}Fe{sub 0.25}In{sub 1.25}S{sub 3}

Energy Technology Data Exchange (ETDEWEB)

Gusejnov, G G; Musaeva, N N; Kyazumov, M G [NAN Azerbajdzhana, Inst. Fiziki, Baku (Azerbaijan); Asadova, I B; Aliev, O M [NAN Azerbajdzhana, Inst. Neorganicheskoj i Fizicheskoj Khimii, Baku (Azerbaijan)

2003-09-01

Single crystals of Ga{sub 0.5}Fe{sub 0.5}InS{sub 3} are grown by the method of chemical gas-transport reactions and those of Ga{sub 0.5}Fe{sub 0.25}In{sub 1.25}S{sub 3} - by Bridgman method. X-ray diffraction studies reveal that they crystallize in trigonal and rhombohedral systems with lattice parameters of a = 3.796 x 2 A, c = 12.210 A, P3m1; a = 3.786 x 2 A, c = 36.606 A, R3m, respectively. An optical absorption edge in a wide range of photon energy and an energy gap width are determined: E{sub g} = 1.885 eV for Ga{sub 0.5}Fe{sub 0.5}InS{sub 3} and E{sub g} 1.843 eV for Ga{sub 0.5}Fe{sub 0.25}In{sub 1.25}S{sub 3}.

Validación del método analítico para el control de la calidad y estudio de estabilidad de ketotifeno colirio 0,025 % Validation of analytical method to quality control and the stability study of 0.025 % eyedrops Ketotiphen

Directory of Open Access Journals (Sweden)

Yenilen Troche Concepción

2010-09-01

Full Text Available El colirio de ketotifeno se indica para aliviar los signos y síntomas de las conjuntivitis alérgicas, por ser este un potente antihistamínico H1 que muestra cierta capacidad para inhibir la liberación de histamina y otros mediadores en mastocitos. En este trabajo se desarrolló y validó un método analítico por cromatografía líquida de alta resolución, para el control de la calidad y los estudios de estabilidad del ketotifeno colirio 0,025 %. El método se basó en la separación del principio activo a través una columna cromatográfica Lichrosorb RP-18 (5 µm (250 x 4 mm, con detección ultravioleta a 296 nm, para lo cual se empleó una fase móvil compuesta por una mezcla desgasificada de metanol:buffer fosfato (75:25; pH 8,5 y se le añadió 1 mL de isopropanol por cada 1 000 mL de la mezcla anterior, con una velocidad de flujo de 1,2 mL/min. El método analítico resultó lineal, preciso, específico y exacto en el intervalo de concentraciones estudiadas.The Ketotiphen eyedrop is prescribed to relief the signs and symptoms of allergic conjunctivitis due to its potent H1 antihistaminic effect showing some ability to inhibit the histamine release and other mediators in cases of mastocytosis. The aim of present paper was to develop and validate an analytical method for the high-performance liquid chromatography, to quality control and the stability studies of 0.025 % eyedrop Ketotiphen. Method was based on active principle separation by means of a Lichrosorb RP-18 (5 µm (250 x 4 mm, with UV detection to 296 nm using a mobile phase including a non-gasified mixture of methanol:buffer-phosphate (75:25; pH 8.5 adding 1 mL of Isopropanol by each 1 000 mL of the previous mixture at a 1.2 mL/min flow velocity. The analytical method was linear, accurate, specific and exact during the study concentrations.

The Eucalyptus grandis R2R3-MYB transcription factor family: evidence for woody growth-related evolution and function.

Science.gov (United States)

Soler, Marçal; Camargo, Eduardo Leal Oliveira; Carocha, Victor; Cassan-Wang, Hua; San Clemente, Hélène; Savelli, Bruno; Hefer, Charles A; Paiva, Jorge A Pinto; Myburg, Alexander A; Grima-Pettenati, Jacqueline

2015-06-01

The R2R3-MYB family, one of the largest transcription factor families in higher plants, controls a wide variety of plant-specific processes including, notably, phenylpropanoid metabolism and secondary cell wall formation. We performed a genome-wide analysis of this superfamily in Eucalyptus, one of the most planted hardwood trees world-wide. A total of 141 predicted R2R3-MYB sequences identified in the Eucalyptus grandis genome sequence were subjected to comparative phylogenetic analyses with Arabidopsis thaliana, Oryza sativa, Populus trichocarpa and Vitis vinifera. We analysed features such as gene structure, conserved motifs and genome location. Transcript abundance patterns were assessed by RNAseq and validated by high-throughput quantitative PCR. We found some R2R3-MYB subgroups with expanded membership in E. grandis, V. vinifera and P. trichocarpa, and others preferentially found in woody species, suggesting diversification of specific functions in woody plants. By contrast, subgroups containing key genes regulating lignin biosynthesis and secondary cell wall formation are more conserved across all of the species analysed. In Eucalyptus, R2R3-MYB tandem gene duplications seem to disproportionately affect woody-preferential and woody-expanded subgroups. Interestingly, some of the genes belonging to woody-preferential subgroups show higher expression in the cambial region, suggesting a putative role in the regulation of secondary growth. © 2014 The Authors New Phytologist © 2014 New Phytologist Trust.

Abscisic Acid Induced Changes in Production of Primary and Secondary Metabolites, Photosynthetic Capacity, Antioxidant Capability, Antioxidant Enzymes and Lipoxygenase Inhibitory Activity of Orthosiphon stamineus Benth.

Directory of Open Access Journals (Sweden)

Mohd Hafiz Ibrahim

2013-07-01

Full Text Available An experiment was conducted to investigate and distinguish the relationships in the production of total phenolics, total flavonoids, soluble sugars, H2O2, O2−, phenylalanine ammonia lyase (PAL activity, leaf gas exchange, antioxidant activity, antioxidant enzyme activity [ascorbate peroxidase (APX, catalase (CAT, superoxide dismutase (SOD and Lipoxygenase inhibitory activity (LOX] under four levels of foliar abscisic acid (ABA application (0, 2, 4, 6 µM for 15 weeks in Orthosiphon stamineus Benth. It was found that the production of plant secondary metabolites, soluble sugars, antioxidant activity, PAL activity and LOX inhibitory activity was influenced by foliar application of ABA. As the concentration of ABA was increased from 0 to 6 µM the production of total phenolics, flavonoids, sucrose, H2O2, O2−, PAL activity and LOX inhibitory activity was enhanced. It was also observed that the antioxidant capabilities (DPPH and ORAC were increased. This was followed by increases in production of antioxidant enzymes APX, CAT and SOD. Under high application rates of ABA the net photosynthesis and stomatal conductance was found to be reduced. The production of primary and secondary metabolites displayed a significant positive relationship with H2O2 (total phenolics, r2 = 0.877; total flavonoids, r2 = 0.812; p ≤ 0.05 and O2− (total phenolics, r2 = 0.778; total flavonoids, r2 = 0.912; p ≤ 0.05. This indicated that increased oxidative stress at high application rates of ABA, improved the production of phytochemicals.

Phosphate removal from aqueous solutions using polyaniline/ Ni 0.5 Zn 0.5 Fe 2 O 4 magnetic nanocomposite

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Mohammad Hossein Tarmahi

2017-05-01

Full Text Available Background: Phosphorus is an indispensable element for the growth of animals and plants. There are several environmental problems related to phosphate; therefore, the technical and economic methods of removing phosphate are of great importance. This study evaluated the efficiency of polyaniline/ Ni0.5Zn0.5Fe2O4 magnetic nanocomposite in removing phosphate from aqueous environments. Methods: The adsorbent was characterized by several methods, including X-ray diffraction (XRD, scanning electron microscopy (SEM, vibrating sample magnetometer (VSM, and Fourier transform infrared (FT-IR spectroscopy. Then, the potential of the adsorbentto adsorb phosphate was investigated. The effects of the parameters of contact time (5-60 minutes, pH (3-9, adsorbent dosage (0.05-0.6 g, and initial phosphate concentration (2-100 mg/L on the phosphate removal yield were studied. All phosphate ion concentrations were measured using the ammonium molybdate spectrophotometric method. Results: The results showed that a time of 30 minutes, pH of 5, and adsorbent dose of 0.4 g were the optimum conditions for phosphate removal through adsorption. Increasing the initial concentration of phosphate from 2 to 100 mg/L decreased the removal efficiency from 90.3% to 32%. The experimental data was fitted well with the Freundlich isotherm model (R2 = 0.997. Conclusion: Polyaniline/Ni0.5Zn0.5Fe2O4 magnetic nanocomposite removes phosphate from aqueous solutions with a simple and environmentally benign procedure. The maximum adsorption capacity based on Langmuir isotherm (R2 = 0.931 is 85.4 mg/g. This magnetic nanocomposite is applicable in managing water resource pollution caused by phosphate ions.

Gender-specific association between tobacco smoking and central obesity among 0.5 million Chinese people: the China Kadoorie Biobank Study.

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Jun Lv

Full Text Available Lifestyle factors are well-known important modifiable risk factors for obesity; the association between tobacco smoking and central obesity, however, is largely unknown in the Chinese population. This study examined the relationship between smoking and central obesity in 0.5 million Chinese adults, a population with a low prevalence of general obesity, but a high prevalence of central obesity.A total of 487,527 adults (200,564 males and 286,963 females, aged 30-79 years, were enrolled in the baseline survey of the China Kadoorie Biobank (CKB Study conducted during 2004-2008. Waist circumference (WC and WC/height ratio (WHtR were used as measures of central obesity.The prevalence of regular smokers was significantly higher among males (60.6% than among females (2.2%. The prevalence of central obesity increased with age and BMI levels, with a significant gender difference (females>males. Of note, almost all obese adults (99.4% were centrally obese regardless of gender. In multivariable regression analyses, adjusting for age, education, physical activity, alcohol use and survey site, regular smoking was inversely associated with BMI in males (standardized regression coefficients, β= -0.093, p<0.001 and females (β= -0.025, p<0.001. Of interest, in the BMI stratification analyses in 18 groups, all βs of regular smoking for WHtR were positive in both genders; the βs showed a significantly greater increasing trend with increasing BMI in males than in females. In the analyses with model adjustment for BMI, the positive associations between regular smoking and WHtR were stronger in males (β= 0.021, p<0.001 than in females (β= 0.008, p<0.001 (p<0.001 for gender difference. WC showed considerably consistent results.The data indicate that tobacco smoking is an important risk factor for central obesity, but the association is gender-specific and depends on the adjustment for general obesity.

Clinical effectiveness of secondary interventions for restenosis after renal artery stenting

Science.gov (United States)

Simone, Thomas A.; Brooke, Benjamin S.; Goodney, Philip P.; Walsh, Daniel B.; Stone, David H.; Powell, Richard J.; Cronenwett, Jack L.; Nolan, Brian W.

2013-01-01

Objective Secondary interventions for renal artery restenosis (RAS) after renal artery stenting are common, despite limited data about their effectiveness. This study was designed to evaluate the outcomes of endovascular treatment of recurrent RAS. Methods We conducted a retrospective review of patients who underwent renal artery stenting between 2001 and 2011 at Dartmouth-Hitchcock Medical Center. Patients who required secondary interventions were compared with control patients who underwent only primary interventions for RAS. Multivariate regression models were used to identify factors associated with successful outcomes, as measured by changes in blood pressure, estimated glomerular filtration rate, and number of antihypertensive medications required. Results Sixty-five secondary (57 patients) renal interventions were undertaken for recurrent RAS associated with progressive hypertension or renal dysfunction and compared with outcomes after 216 primary (180 patients) renal artery stenting procedures. Patients undergoing primary vs secondary interventions did not differ significantly in the number of preoperative antihypertensive medications used, comorbid conditions, or blood pressure. All primary and secondary interventions were performed with stents and showed no difference in procedural complications. At a mean follow-up of 23 months (range, 1–128 months), similar improvements in renal function and blood pressure were found between patients undergoing primary and secondary interventions, and there was no difference in rates of restenosis or survival between cohorts. Regression models showed that the use of embolic protection devices was associated with improved renal function after primary (odds ratio [OR], 2.0; 95% confidence interval [CI], 1.1–3.8; P < .05) and secondary (OR, 4.7; 95% CI, 1.7–12.5; P < .05) interventions, whereas statin therapy was associated with improved renal (OR, 2.0; 95% CI, 1.3–3.2; P < .05) and blood pressure response (OR, 4

Propagation characteristics of a focused laser beam in a strontium barium niobate photorefractive crystal under reverse external electric field.

Science.gov (United States)

Guo, Q L; Liang, B L; Wang, Y; Deng, G Y; Jiang, Y H; Zhang, S H; Fu, G S; Simmonds, P J

2014-10-01

The propagation characteristics of a focused laser beam in a SBN:75 photorefractive crystal strongly depend on the signal-to-background intensity ratio (R=Is/Ib) under reverse external electric field. In the range 20>R>0.05, the laser beam shows enhanced self-defocusing behavior with increasing external electric field, while it shows self-focusing in the range 0.03>R>0.01. Spatial solitons are observed under a suitable reverse external electric field for R=0.025. A theoretical model is proposed to explain the experimental observations, which suggest a new type of soliton formation due to "enhancement" not "screening" of the external electrical field.

New Comparative Analysis Based on the Secondary Structure of SSU-rRNA Gene Reveals the Evolutionary Trend and the Family-Genus Characters of Mobilida (Ciliophora, Peritrichia).

Science.gov (United States)

Zhang, Yong; Zhao, Yuan-Jun; Wang, Qin; Tang, Fa-Hui

2015-08-01

In order to reveal the structural evolutionary trend of Mobilida ciliates, twenty-six SSU-rRNA sequences of mobilid species, including seven ones newly sequenced in the present work, were used for comparative phylogenic analysis based on the RNA secondary structure. The research results indicate that all the secondary structures except domains Helix 10, Helix 12, and Helix 37 could be regarded as the criterions in classification between the family Trichodinidae and Urceolariida, and four regions including Helix E10-1, Helix 29, Helix 43, and Helix 45-Helix 46 could be as criterions in classification between the genus Trichodinella and Trichodina in family Trichodinidae. After the analysis of common structural feature within the Mobilida, it was found that the secondary structure of V6 could prove the family Urceolariidae primitive status. This research has further suggested that the genus Trichodina could be divergent earlier than Trichodinella in the family Trichodinidae. In addition, the relationship between the secondary structure and topology of phylogenic tree that the branching order of most clades corresponds with the secondary structure of species within each clade of phylogenetic tree was first uncovered and discussed in the present study.

Learning Strategies: Secondary LD Students in the Mainstream.

Science.gov (United States)

D'Antoni, Alice; And Others

The paper presents four learning strategy techniques--the SQ3R method of study, the Multipass Strategy, the Advanced Study Guide Technique, and Cognitive Mapping--for use with secondary level learning disabled students. The SQ3R method involves the five steps of survey, question, read, recite, and review. An adaption of the SQ3R method, the…

Direct amination of secondary alcohols using Ammonia

NARCIS (Netherlands)

Pingen, D.L.L.; Müller, C.; Vogt, D.

2010-01-01

Hydrogen shuttle: For the first time secondary alcohols and ammonia can be directly converted into primary amines with a selectivity of up to 99¿% by using a simple ruthenium/phosphine catalyst (see scheme; R1, R2= alkyl, aryl, alkenyl; M=[Ru3(CO)12]; and L=phosphine ligand).

Crystal structure and Mössbauer effect in multiferroic 0.5BiFeO3-0.5Pb(Fe0.5Ta0.5O3 solid solution

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Stoch Agata

2017-06-01

Full Text Available Multiferroic 0.5BiFeO3-0.5Pb(Fe0.5Ta0.5O3 solid solution is a material that exhibits ferroelectric and antiferromagnetic orderings in ambient temperature. The solid solution was obtained as a result of a conventional reaction in a solid state. The obtained material is a dense, fine-grained sinter whose surface was observed by scanning electron microscopy (SEM and stoichiometry was confirmed by energy dispersive X-ray spectroscopic (EDS analysis. According to the X-ray powder diffraction (XRD measurements, the main phase is R3c space group with admixture of Pm-3m regular phase. Small contribution of pyrochlore-like phase was also observed. Mössbauer spectroscopy suggested random distribution of Fe3+/Ta5+ cations in the B sites of ABO3 compound. Reduction of the magnetic hyperfine field with an increase in the substitution of Ta5+ in Fe3+ neighbourhood was also observed.

1-Hz rTMS in the treatment of tinnitus: A sham-controlled, randomized multicenter trial.

Science.gov (United States)

Landgrebe, Michael; Hajak, Göran; Wolf, Stefan; Padberg, Frank; Klupp, Philipp; Fallgatter, Andreas J; Polak, Thomas; Höppner, Jacqueline; Haker, Rene; Cordes, Joachim; Klenzner, Thomas; Schönfeldt-Lecuona, Carlos; Kammer, Thomas; Graf, Erika; Koller, Michael; Kleinjung, Tobias; Lehner, Astrid; Schecklmann, Martin; Pöppl, Timm B; Kreuzer, Peter; Frank, Elmar; Langguth, Berthold

Chronic tinnitus is a frequent, difficult to treat disease with high morbidity. This multicenter randomized, sham-controlled trial investigated the efficacy and safety of 1-Hz repetitive transcranial magnetic stimulation (rTMS) applied to the left temporal cortex in patients with chronic tinnitus. Tinnitus patients were randomized to receive 10 sessions of either real or sham 1-Hz-rTMS (2000 stimuli, 110% motor threshold) to the left temporal cortex. The primary outcome was the change in the sum score of the tinnitus questionnaire (TQ) of Goebel and Hiller from baseline to end of treatment. A total of 163 patients were enrolled in the study (real rTMS: 75; sham rTMS: 78). At day 12, the baseline mean of 43.1 TQ points in 71 patients assigned to real rTMS changed by -0.5 points; it changed by 0.5 points from a baseline of 42.1 in 75 patients randomized to sham rTMS (adjusted mean difference between groups: -1.0; 95.19% confidence interval: -3.2 to 1.2; p = 0.36). All secondary outcome measures including measures of depression and quality of life showed no significant differences either (p > 0.11). The number of participants with side-effects or adverse events did not differ between groups. Real 1-Hz-rTMS over the left temporal cortex was well tolerated but not superior compared with sham rTMS in improving tinnitus severity. These findings are in contrast to results from studies with smaller sample sizes and put the efficacy of this rTMS protocol for treatment of chronic tinnitus into question. Controlled Trials: http://www.isrctn.com/ISRCTN89848288. Copyright © 2017 Elsevier Inc. All rights reserved.

Collaborative learning in a culturally diverse secondary vocational education

NARCIS (Netherlands)

Dr. Rutger van de Sande; Drs. Kennedy Aquilino Tielman; Dr. S. Bolhuis; Prof. dr. Perry den Brok

2010-01-01

Collaborative learning in a culturally diverse secondary vocational education. By K. Tielman (Fontys), P. den Brok (ESoE), S. Bolhuis (Fontys) and R. van de Sande (Fontys) This contribution discusses a descriptive study on the experiences of students and teachers in secondary vocational education

Isolation, pure culture and characterization of Serratia symbiotica sp. nov., the R-type of secondary endosymbiont of the black bean aphid Aphis fabae.

Science.gov (United States)

Sabri, Ahmed; Leroy, Pascal; Haubruge, Eric; Hance, Thierry; Frère, Isabelle; Destain, Jacqueline; Thonart, Philippe

2011-09-01

An intracellular symbiotic bacterium was isolated from the flora of a natural clone of the black bean aphid Aphis fabae. The strain was able to grow freely in aerobic conditions on a rich medium containing 1 % of each of the following substrates: glucose, yeast extract and casein peptone. Pure culture was achieved through the use of solid-phase culture on the same medium and the strain was designated CWBI-2.3(T). 16S rRNA gene sequence analysis revealed that strain CWBI-2.3(T) was a member of the class Gammaproteobacteria, having high sequence similarity (>99 %) with 'Candidatus Serratia symbiotica', the R-type of secondary endosymbiont that is found in several aphid species. As strain CWBI-2.3(T) ( = LMG 25624(T) = DSM 23270(T)) was the first R-type symbiont to be isolated and characterized, it was designated as the type strain of Serratia symbiotica sp. nov.

Nanocrystalline (U0.5Ce0.5)O2±x solid solutions through citrate gel-combustion

Science.gov (United States)

Maji, D.; Ananthasivan, K.; Venkata Krishnan, R.; Balakrishnan, S.; Amirthapandian, S.; Joseph, Kitheri; Dasgupta, Arup

2018-04-01

Nanocrystalline powders of (U0.5Ce0.5)O2±x solid solutions were synthesized in bulk (100-200 g) through the citrate gel combustion. The fuel (citric acid) to oxidant (nitrate) mole ratio (R) was varied from 0.1 to 1.0. Two independent lots of the products obtained through the gel-combustion were calcined at 973 K in air and in a mixture of argon containing 8% H2 respectively. All these powders were characterized for their bulk density, X-ray crystallite size, specific surface area, size distribution of the particles, porosity as well as residual carbon. The morphology and microstructures of these powders were studied by using scanning electron microscopy (SEM) and transmission electron microscopy (TEM) respectively. Nanocrystalline single phase fluorite solid solutions having a typical crystallite size of about (7-15 nm) were obtained. These powders were highly porous comprising cuboidal flaky agglomerates. The combustion mixture with an 'R' value of 0.25 was found to undergo volume combustion and was found to yield a product that was distinctly different. The systematic investigation on synthesis and characterization of nanocrystalline UCeO2 is reported for the first time.

Structural and Mössbauer spectroscopy characterization of bulk and nanostructured TiFe{sub 0.5} Ni{sub 0.5}/graphite compounds and their hydrides

Energy Technology Data Exchange (ETDEWEB)

Martínez, M. A. R., E-mail: fisicorodriguez@gmail.com; André-Filho, J.; Félix, L. L.; Coaquira, J. A. H.; Garg, V. K.; Oliveira, A. C. [Universidade de Brasília, Instituto de Física, Núcleo de Física Aplicada (Brazil); Mestnik-Filho, J. [Instituto de Pesquisas energéticas e Nucleares, IPEN-CNEN/SP (Brazil)

2015-06-15

The structural and hyperfine properties of bulk TiFe{sub 0.5}Ni{sub 0.5} intermetallic and ball-milled TiFe{sub 0.5}Ni{sub 0.5}/graphite compounds and their hydrides have been studied. The bulk and nanostructured TiFe{sub 0.5}Ni{sub 0.5} compounds crystallize in the cubic crystal structure of CsCl (B2). After hydrogenation, the formation of hydrogen-poor phase (∝-phase) and hydride phase (β-phase) have been determined for the bulk compound. However, the formation of the ∝-phase and the hydrogen-richest phase (γ-phase) and other secondary phases have been determined for the ball-milled TiFe{sub 0.5}Ni{sub 0.5}/graphite sample. It has been determined that the ball-milled TiFe{sub 0.5}Ni{sub 0.5}/graphite sample presents a large amount of the γ-phase which indicates that the presence of graphite nearby nanostructured intermetallic grains enhances the absorption of hydrogen. Mossbauer results are consistent with the structural results. Meanwhile, no significant changes in the isomer shift (IS) value has been determined for the α-phase with respect to the intermetallic compound, a strong increase in the IS value has been determined for the β- and γ-phases with respect to the ∝-phase. That increase indicates a decrease of the s-electron density at the Fe nuclei due to the charge transfer from the metal to the nearby hydrogen atoms.

Topology and temperature dependence of the diffuse X-ray scattering in Na0.5Bi0.5TiO3 ferroelectric single crystals.

Science.gov (United States)

Gorfman, Semën; Keeble, Dean S; Bombardi, Alessandro; Thomas, Pam A

2015-10-01

The results of high-resolution measurements of the diffuse X-ray scattering produced by a perovskite-based Na 0.5 Bi 0.5 TiO 3 ferroelectric single crystal between 40 and 620 K are reported. The study was designed as an attempt to resolve numerous controversies regarding the average structure of Na 0.5 Bi 0.5 TiO 3 , such as the mechanism of the phase transitions between the tetragonal, P 4 bm , and rhombohedral | monoclinic, R 3 c  |  Cc , space groups and the correlation between structural changes and macroscopic physical properties. The starting point was to search for any transformations of structural disorder in the temperature range of thermal depoling (420-480 K), where the average structure is known to remain unchanged. The intensity distribution around the {032} pseudocubic reflection was collected using a PILATUS 100K detector at the I16 beamline of the Diamond Light Source (UK). The data revealed previously unknown features of the diffuse scattering, including a system of dual asymmetric L-shaped diffuse scattering streaks. The topology, temperature dependence, and relationship between Bragg and diffuse intensities suggest the presence of complex microstructure in the low-temperature R 3 c  |  Cc phase. This microstructure may be formed by the persistence of the higher-temperature P 4 bm phase, built into a lower-temperature R 3 c  |  Cc matrix, accompanied by the related long-range strain fields. Finally, it is shown that a correlation between the temperature dependence of the X-ray scattering features and the temperature regime of thermal depoling is present.

Study of xCo{sub 0.8}Ni{sub 0.2}Fe{sub 2}O{sub 4}+(1−x) Pb{sub 0.99625} La{sub 0.0025}Zr{sub 0.55}Ti{sub 0.45}O{sub 3} magnetoelectric composites

Energy Technology Data Exchange (ETDEWEB)

Dipti [Electroceramics Research Lab, G.V.M. Girls College, Sonepat 131001 (India); School of Physics & Materials Science, Thapar University, Patiala 147004 (India); Singh, Sangeeta, E-mail: Sangeetaasingh@gmail.com [Department of Physics, G.V.M. Girls College, Sonepat 131001 (India); Juneja, J.K. [Department of Physics, Hindu College, Sonepat 131001 (India); Raina, K.K. [School of Physics & Materials Science, Thapar University, Patiala 147004 (India); Dehradun Institute of Technology, DIT University, Dehradun 248009 (India); Kotnala, R.K. [National Physical Laboratory, Dr. K.S. Krishnan Marg, New Delhi 110012 (India); Prakash, Chandra [Solid State Physics Laboratory, Lucknow Road, Delhi 110054 (India)

2016-06-01

We are reporting here, the studies of the structural, dielectric, ferroelectric and magnetic properties of magnetoelectric composites of La modified lead zirconate titanate (PLZT) and Ni modified cobalt ferrite (CNFO) with compositional formula xCo{sub 0.8}Ni{sub 0.2}Fe{sub 2}O{sub 4}+(1−x) Pb{sub 0.99625}La{sub 0.0025}Zr{sub 0.55}Ti{sub 0.45}O{sub 3} (x=0.00, 0.05, 0.10, 0.15 and 1.00 by weight) prepared by the solid state reaction method. Coexistence of both the phases in composites was confirmed by X-Ray diffraction technique. The microstructure and average grain size were determined from Scanning Electron Micrograph (SEM) in backscattered mode. Both the phases could be observed clearly. The variations of dielectric properties with frequency and temperature were also studied. P–E and M–H hysteresis measurements were carried. Magnetoelectric coupling (ME) coefficient for samples with x=0.05 and 0.10 were measured as a function of DC magnetic field. Maximum value of ME coefficient (1.2 mV/cm Oe) and piezoelectric coefficient (96 pC/N) for x=0.05 were observed. - Highlights: • ME composites PLZT–CNFO were studied for various properties. • Substitution of Ni and La in CFO and in PZT phase improves ME Coefficient. • The samples are good for various application due to high ME coeff. of PLZT-CNFO.

Very large refrigerant capacity at room temperature with reproducible magnetocaloric effect in Fe0.975Ni0.025Rh

International Nuclear Information System (INIS)

Manekar, Meghmalhar; Roy, S B

2011-01-01

We present the results of magnetocaloric effect (MCE) measurements on Fe 0.975 Ni 0.025 Rh. The MCE is estimated using both the isothermal field-dependent magnetization and the temperature-dependent magnetization in constant magnetic fields. We find a very large effective refrigerant capacity of nearly 492.8 J kg -1 , with the hot end at about 307 K, which is reproducible over many field cycles. We compare this refrigerant capacity with those of two well known systems, namely Gd 5 Ge 1.9 Si 2 Fe 0.1 and MnFeP 0.45 As 0.55 , which show a large MCE near room temperature, and also with our earlier results on the parent Fe-Rh alloy. The large effective refrigerant capacity in our sample is one of the largest achieved yet at room temperature with a significant improvement over the parent Fe-Rh system. (fast track communication)

Secondary arsenic minerals in the environment: A review

Czech Academy of Sciences Publication Activity Database

Drahota, P.; Filippi, Michal

2009-01-01

Roč. 35, č. 8 (2009), s. 1243-1255 ISSN 0160-4120 R&D Projects: GA AV ČR KJB300130702 Institutional research plan: CEZ:AV0Z30130516 Keywords : arsenic * secondary arsenic mineral * environmental sample * solubility * environmental stability Subject RIV: DD - Geochemistry Impact factor: 4.786, year: 2009

Phase equilibria in the Tl2MoO4–R2(MoO43–Zr(MoO42 (R = Al, Cr systems: synthesis, structure and properties of new triple molybdates Tl5RZr(MoO46 and TlRZr0.5(MoO43

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V. G. Grossman

2017-12-01

Full Text Available The Tl2MoO4–R2(MoO43–Zr(MoO42 (R = Al, Cr systems were studied in the subsolidus region using X-ray powder diffraction and differential scanning calorimetric (DSC analysis. Quasi-binary joins were revealed, and triangulation was carried out. New ternary molybdates: Tl5RZr(MoO46 (5:1:2 and TlRZr0.5(MoO43 (1:1:1 (R = Al, Cr were prepared. The unit cell parameters for the new compounds were calculated.

Li distribution characterization in Li-ion batteries positive electrodes containing LixNi0.8Co0.15Al0.05O2 secondary particles (0.75 ⩽ x ⩽ 1.0)

International Nuclear Information System (INIS)

Mima, K.; Gonzalez-Arrabal, R.; Azuma, H.; Yamazaki, A.; Okuda, C.; Ukyo, Y.; Sawada, H.; Fujita, K.; Kato, Y.; Perlado, J.M.; Nakai, S.

2012-01-01

The elemental distribution of as-received (non-charged) and charged Li-ion battery positive electrodes containing Li x Ni 0.8 Co 0.15 Al 0.05 O 2 (0.75 ⩽ x ⩽ 1.0) microparticles as active material is characterized by combining μ-PIXE and μ-PIGE techniques. PIGE measurements evidence that the Li distribution is inhomogeneous (existence of Li-rich and Li-depleted regions) in as-received electrodes corresponding with the distribution of secondary particles but it is homogeneous within the studied individual secondary micro-particles. The dependence of the Li distribution on electrode thickness and on charging conditions is characterized by measuring the Li distribution maps in specifically fabricated cross-sectional samples. These data show that decreasing the electrode thickness down to 35 μm and charging the batteries at slow rate give rise to more homogeneous Li depth profiles.

Bloqueio peribulbar com a associação da mistura enantiomérica de bupivacaína (S75-R25 a 0,5% e lidocaína a 2%: efeitos da adição de hialuronidase Bloqueo peribulbar con la asociación de la mezcla enantiomérica de bupivacaína (S75-R25 a 0,5% y lidocaína a 2%: efectos de la adición de hialuronidasa Peribulbar block with the association of 0.5% enantiomeric mixture of bupivacaine (S75-R25 and 2% lidocaine: effects of hyaluronidase addition

Directory of Open Access Journals (Sweden)

Luiz Fernando Soares

2002-07-01

Full Text Available JUSTIFICATIVA E OBJETIVOS: Os benefícios da adição de hialuronidase ao anestésico local em bloqueio peribulbar permanecem controversos. Este estudo comparou os efeitos da hialuronidase sobre a acinesia dos músculos retos, elevador da pálpebra e orbicular do olho após a realização de bloqueio peribulbar com a associação da mistura enantiomérica de bupivacaína (S75-R25 a 0,5% e lidocaína a 2%. MÉTODO: Foram estudados 35 pacientes divididos em grupo 1, que recebeu uma combinação de iguais volumes de mistura enantiomérica de bupivacaína (S75-R25 a 0,5% e lidocaína a 2% com adrenalina 5 µg.ml-1 e grupo 2, que recebeu a mesma solução anestésica adicionada de hialuronidase 50 UI.ml-1. A motilidade dos músculos retos, orbicular do olho e elevador da pálpebra foi avaliada 1, 5, 10 e 15 minutos após o bloqueio. RESULTADOS: Os escores de motilidade dos músculos extra-oculares diminuíram significativamente durante o período de observação, sem diferenças entre os grupos. Os percentuais de pacientes que apresentaram acinesia do globo ocular em cada momento do estudo não diferiram significativamente entre os grupos. Os escores de dor à injeção do anestésico local não diferiram entre os grupos. A anestesia cirúrgica foi satisfatória em todos os pacientes. CONCLUSÕES: Este estudo não demonstrou nenhum efeito da adição de hialuronidase na concentração de 50 UI.ml-1 sobre a acinesia dos músculos retos, elevador da pálpebra e orbicular do olho durante a instalação de bloqueio peribulbar realizado com a associação da mistura enantiomérica de bupivacaína (S75-R25 a 0,5% e lidocaína a 2% com adrenalina 5 µg.ml-1.JUSTIFICATIVA Y OBJETIVOS: Los beneficios de la adición de hialuronidasa al anestésico local en bloqueo peribulbar permanecen en controversia. Este estudio comparó los efectos de la hialuronidasa sobre la acinesia de los músculos rectos, elevador de la pálpebra y orbicular del ojo después de la

Limited and selective transfer of plasma membrane glycoproteins to membrane of secondary lysosomes

International Nuclear Information System (INIS)

Haylett, T.; Thilo, L.

1986-01-01

Radioactive galactose, covalently bound to cell surface glycoconjugates on mouse macrophage cells, P388D 1 , was used as a membrane marker to study the composition, and the kinetics of exchange, of plasma membrane-derived constituents in the membrane of secondary lysosomes. Secondary lysosomes were separated from endosomes and plasma membrane by self-forming Percoll density gradients. Horseradish peroxidase, taken up by fluid-phase pinocytosis, served as a vesicle contents marker to monitor transfer of endosomal contents into secondary lysosomes. Concurrently, the fraction of plasma membrane-derived label of secondary lysosomes increased by first order kinetics from 4 PAGE, labeled molecules of M/sub r/ 160-190 kD were depleted and of the M/sub r/ 100-120 kD were enriched in lysosome membrane compared with the relative composition of label on the cell surface. No corresponding selectivity was observed for the degradation of label, with all M/sub r/ classes being affected to the same relative extent. The results indicate that endocytosis-derived transfer of plasma membrane constitutents to secondary lysosomes is a limited and selective process, and that only ∼1% of internalized membrane is recycled via a membrane pool of secondary lysosomes

Dielectric, piezoelectric properties of MnO2-doped (K0.5Na0.5)NbO3–0.05LiNbO3 crystal grown by flux-Bridgman method

International Nuclear Information System (INIS)

Liu, Ying; Xu, Guisheng; Liu, Jinfeng; Yang, Danfeng; Chen, Xiaxia

2014-01-01

Highlights: • KNN–0.05LN based single crystals were grown by flux-Bridgman method. • Dielectric, piezoelecrc and ferroelectric properties were studied. • The effect of MnO 2 doping on the crystals' properties. • Dielectric and other properties were improved due to MnO 2 doping. - Abstract: Lead-free potassium sodium niobate piezoelectric single crystals substituted with lithium and then doped with MnO 2 (K 0.5 Na 0.5 )NbO 3 –0.05LiNbO 3 –yMnO 2 (y = 0%, 1.0% and 1.5%) (abbreviated as KNN–0.05LN–yMnO 2 ) have been grown by flux-Bridgman method using KCl–K 2 CO 3 eutectic composition as the flux. Their actual composition as well as the dielectric and piezoelectric properties were studied. Their actual composition deviated from the ratio of the raw materials due to different segregation coefficients of K and Na. The orthorhombic–tetragonal (T o–t ) and tetragonal–cubic phase transition temperature (the Curie temperature T c ) of the single crystal appears at 186 °C and 441 °C, respectively, for KNN–0.05LN–1.0%MnO 2 , shift to higher temperatures compared with that of pure KNN–0.05LN crystals, according to the dielectric permittivity versus temperature loops. The KNN–0.05LN–1.0%MnO 2 (001) plate shows higher piezoelectric coefficient d 33 and dielectric permittivity ε r when compared with pure KNN–0.05LN crystal, being on the order of 226 pC/N and 799 (161 pC/N and 530 for KNN–0.05LN), respectively. These excellent properties show that MnO 2 dopant is effective in improving KNN–0.05LN based piezoelectric crystals

Structural change of Li{sub 1-x}Ni{sub 0.5}Mn{sub 0.5}O{sub 2} cathode materials for lithium-ion batteries by synchrotron radiation

Energy Technology Data Exchange (ETDEWEB)

Arachi, Yoshinori; Tanaka, Minoru; Asai, Takeshi [Kansai Univ., Faculty of Engineering, Unit of Chemistry, Suita, Osaka (Japan); Kobayashi, Hironori [National Inst. of Advanced Industrial Science and Technology (AIST), Ikeda, Osaka (Japan); Emura, Shuichi [Osaka Univ., ISIR, Ibaraki, Osaka (Japan); Nakata, Yoshiyuki [Iwakimeisei Univ., Faculty of Science and Engineering, Iwaki, Fukushima (Japan)

2003-01-01

Synchrotron X-ray diffraction and XAFS measurement have been employed to investigate structural change and the charging process of a layered LiNi{sub 0.5}Mn{sub 0.5}O{sub 2} cathode material. The structure of charged Li{sub 1-x}Ni{sub 0.5}Mn{sub 0.5}O{sub 2} (x = 0.5), which corresponds to the composition for showing rechargeable capacity, was determined. The results showed that divalent nickel metal was oxidized to trivalent after charging, in association with the phase transition from hexagonal (R3-bar m) to monoclinic (C2/m) resulting from the ordering of cations in the layered structure. (author)

A method for rapid similarity analysis of RNA secondary structures

Directory of Open Access Journals (Sweden)

Liu Na

2006-11-01

Full Text Available Abstract Background Owing to the rapid expansion of RNA structure databases in recent years, efficient methods for structure comparison are in demand for function prediction and evolutionary analysis. Usually, the similarity of RNA secondary structures is evaluated based on tree models and dynamic programming algorithms. We present here a new method for the similarity analysis of RNA secondary structures. Results Three sets of real data have been used as input for the example applications. Set I includes the structures from 5S rRNAs. Set II includes the secondary structures from RNase P and RNase MRP. Set III includes the structures from 16S rRNAs. Reasonable phylogenetic trees are derived for these three sets of data by using our method. Moreover, our program runs faster as compared to some existing ones. Conclusion The famous Lempel-Ziv algorithm can efficiently extract the information on repeated patterns encoded in RNA secondary structures and makes our method an alternative to analyze the similarity of RNA secondary structures. This method will also be useful to researchers who are interested in evolutionary analysis.

[Clinical study of aged patients with secondary benign paroxysmal positional vertigo].

Science.gov (United States)

Zhu, Z J; Wei, L P; Xu, Z X; Xu, H J; Liu, Q; Luo, N

2017-09-07

Objective: To investigate the clinical features and evaluate the efficacy of manual reduction in treatment of age patients with secondary benign paroxysmal positional vertigo (s-BPPV). Methods: Thirty-two cases of aged patients ( the s-BPPV group: including 19 cases of female and 13 males, age from 60 to 86 years old)with secondary benign paroxysmal positional vertigo from Jul. 2013 to Sep. 2015 in our hospital were retrospectively analyzed. The results were compared with 121 patients( the primary group: including 82 cases of female and 39males, aged from 60 to 86 years old)with aged primary benign paroxysmal positional vertigo(p -BPPV). All the patients were followed up for 12 months. Statistical data analysis was carried out with SPSS 19.0. Results: 20.92%(32/153)of all the observed elderly patients with BPPV was the aged s-BPPV. The sex ratio and onset age had no significant difference between the two groups(χ(2)=0.79, P >0.05; t =0.37, P >0.05). The rate of two or more semicircular canal involvement in the secondary group(21.88%) was higher than that in primary group(6.61%)(χ(2)=6.67, P manual reduction was 57.50%(23/40)in secondary group and 82.31%(107/130)in primary group, the difference was significant(χ(2)=10.46, P manual reduction in secondary group and 91.54%(119/130) in primary group, the difference was not significant(χ(2)= 0.59, P >0.05). The numbers of circulation of the first successful manual reduction management were (3.9±1.3)times in secondary group and (2.1±1.1)times in primary group, the difference was significant( t =3.15, P manual reduction of secondary BPPV is lower than primary BPPV, it's needed more circulation of first success in manual reduction management. The total effective rates are not significant in two groups and recurrence rate is relatively high in secondary group.

Dynamic susceptibility contrast (DSC) perfusion MRI in differential diagnosis between radionecrosis and neoangiogenesis in cerebral metastases using rCBV, rCBF and K2.

Science.gov (United States)

Muto, Mario; Frauenfelder, Giulia; Senese, Rossana; Zeccolini, Fabio; Schena, Emiliano; Giurazza, Francesco; Jäger, Hans Rolf

2018-07-01

Distinction between treatment-related changes and tumour recurrence in patients who have received radiation treatment for brain metastases can be difficult on conventional MRI. In this study, we investigated the ability of dynamic susceptibility contrast (DSC) perfusion in differentiating necrotic changes from pathological angiogenesis and compared measurements of relative cerebral blood volume (rCBV), relative cerebral blood flow (rCBF) and K2, using a dedicated software. Twenty-nine patients with secondary brain tumors were included in this retrospective study and underwent DSC perfusion MRI with a 3-month follow-up imaging after chemo- or radiation-therapy. Region-of-interests were drawn around the contrast enhancing lesions and measurements of rCBV, rCBF and K2 were performed in all patients. Based on subsequent histological examination or clinico-radiological follow-up, the cohort was divided in two groups: recurrent disease and stable disease. Differences between the two groups were analyzed using the Student's t test. Sensitivity, specificity and diagnostic accuracy of rCBV measurements were analyzed considering three different cut-off values. Between patients with and without disease, only rCBV and rCBF values were significant (p < 0.05). The only cut-off value giving the best diagnostic accuracy of 100% was rCBV = 2.1 (sensitivity = 100%; specificity = 100%). Patients with tumor recurrence showed a higher mean value of rCBV (mean = 4.28, standard deviation = 2.09) than patients with necrotic-related changes (mean = 0.77, standard deviation = 0.44). DSC-MRI appears a clinically useful method to differentiate between tumor recurrence, tumor necrosis and pseudoprogression in patients treated for cerebral metastases. Relative CBV using a cut-off value of 2.1 proved to be the most accurate and reliable parameter.

Performance of R290 and R1270 for R22 applications with evaporator and condenser temperature variation

International Nuclear Information System (INIS)

Park, Ki Jung; Jung, Dong Soo

2008-01-01

In this study, therma l performance of two hydrocarbon refrigerants of R290 and R1270 was measured in an attempt to substitute R22. They were tested in a heat pump bench tester of 1 ton capacity with a hermetic rotary compressor. Water and water/glycol mixture were employed as the secondary heat transfer fluids in the test bench. All tests were conducted under the same external conditions simulating three different air-conditioning and heat pumping conditions. Test results show that the coefficient of performance of these hydrocarbon refrigerants is up to 11.5% higher than that of R22 under all conditions. Refrigeration capacity of R290 is up to 8.2% lower than that of R22 under normal airconditioning and heat pumping conditions. Under extremely cold temperature conditions, however, the capacity of R290 is 5% higher than that of R22. On the other hand, the capacity of R1270 is similar to that of R22 under all conditions. Compressor discharge temperatures of these hydrocarbons are reduced by 14-31 .deg. C as compared to R22. The amount of charge is reduced up to 58% as compared to R22. Overall, these hydrocarbons provide good performance with reasonable energy savings without any environmental problems and thus can be used as long-term alternatives for residential air-conditioning and heat pumping applications

elPBN neurons regulate rVLM activity through elPBN-rVLM projections during activation of cardiac sympathetic afferent nerves

Science.gov (United States)

Longhurst, John C.; Tjen-A-Looi, Stephanie C.; Fu, Liang-Wu

2016-01-01

The external lateral parabrachial nucleus (elPBN) within the pons and rostral ventrolateral medulla (rVLM) contributes to central processing of excitatory cardiovascular reflexes during stimulation of cardiac sympathetic afferent nerves (CSAN). However, the importance of elPBN cardiovascular neurons in regulation of rVLM activity during CSAN activation remains unclear. We hypothesized that CSAN stimulation excites the elPBN cardiovascular neurons and, in turn, increases rVLM activity through elPBN-rVLM projections. Compared with controls, in rats subjected to microinjection of retrograde tracer into the rVLM, the numbers of elPBN neurons double-labeled with c-Fos (an immediate early gene) and the tracer were increased after CSAN stimulation (P < 0.05). The majority of these elPBN neurons contain vesicular glutamate transporter 3. In cats, epicardial bradykinin and electrical stimulation of CSAN increased the activity of elPBN cardiovascular neurons, which was attenuated (n = 6, P < 0.05) after blockade of glutamate receptors with iontophoresis of kynurenic acid (Kyn, 25 mM). In separate cats, microinjection of Kyn (1.25 nmol/50 nl) into the elPBN reduced rVLM activity evoked by both bradykinin and electrical stimulation (n = 5, P < 0.05). Excitation of the elPBN with microinjection of dl-homocysteic acid (2 nmol/50 nl) significantly increased basal and CSAN-evoked rVLM activity. However, the enhanced rVLM activity induced by dl-homocysteic acid injected into the elPBN was reversed following iontophoresis of Kyn into the rVLM (n = 7, P < 0.05). These data suggest that cardiac sympathetic afferent stimulation activates cardiovascular neurons in the elPBN and rVLM sequentially through a monosynaptic (glutamatergic) excitatory elPBN-rVLM pathway. PMID:27225950

Gastric Lymphoma with Secondary Trigeminal Nerve Lymphoma: A Case Report

Directory of Open Access Journals (Sweden)

Warissara Rongthong

2017-05-01

Full Text Available Data supporting the role of radiotherapy in secondary trigeminal nerve lymphoma is scarce. Here, I report the case of 64-year-old Thai male diagnosed as gastric diffuse large B cell lymphoma with secondary trigeminal nerve lymphoma. He had previously received one cycle of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP, followed by five cycles of rituximab plus CHOP (R-CHOP with intrathecal methotrexate (MTX and cytarabine (Ara-C. One month after the last cycle of R-CHOP, he developed a headache and numbness on the left side of his face. MRI revealed thickening of the left trigeminal nerve. He received one intrathecal injection of MTX and Ara-C, followed by systemic chemotherapy. After receiving intrathecal chemotherapy, his symptoms disappeared. Clinical response and MRI studies suggested secondary trigeminal nerve lymphoma. Two months later, our patient’s secondary trigeminal nerve lymphoma had progressed. Salvage whole brain irradiation (36 Gy with boost dose (50 Gy along the left trigeminal nerve was given. Unfortunately, our patient developed heart failure and expired during the radiotherapy session. In conclusion and specific to secondary central nervous system lymphoma (SCNSL, radiotherapy may benefit patients who fail to respond to systemic chemotherapy and palliative treatment. The results this report fail to support the role of radiotherapy in secondary trigeminal nerve lymphoma.

Coexistence of room temperature ferroelectricity and ferrimagnetism in multiferroic BiFeO3-Bi0.5Na0.5TiO3 solid solution

International Nuclear Information System (INIS)

Tian, Z.M.; Wang, C.H.; Yuan, S.L.; Wu, M.S.; Ma, Z.Z.; Duan, H.N.; Chen, L.

2011-01-01

Highlights: → In this study, the coexistence of ferroelectrics and ferrimagnetism have been observed at room temperature for the (1 - x)BiFeO 3 -xBi 0.5 Na 0.5 TiO 3 (x = 0.37) solid solutions. → X-ray diffraction and Raman spectroscopy measurements show a single-phase perovskite structure with no impurities identified. → A magnetic transition from paramagnetic (PM) to ferrimagnetic (Ferri) ordering is observed for the solution with Curie temperature T C ∼ 330 K. - Abstract: The structure, ferroelectric and magnetic properties of (1 - x)BiFeO 3 -xBi 0.5 Na 0.5 TiO 3 (x = 0.37) solid solution fabricated by a sol-gel method have been investigated. X-ray diffraction and Raman spectroscopy measurements show a single-phase perovskite structure with no impurities identified. Compared with pure BiFeO 3 , the coexistence of ferroelectricity and ferrimagnetism have been observed at room temperature for the solution with remnant polarization P r = 1.41 μC/cm 2 and remnant magnetization M r = 0.054 emu/g. Importantly, a magnetic transition from ferrimagnetic (FM) ordering to paramagnetic (PM) state is observed, with Curie temperature T C ∼ 330 K, being explained in terms of the suppression of cycloid spin configuration by the structural distortion.

Secondary standard dosimetry system with automatic dose/rate calculation

International Nuclear Information System (INIS)

Duftschmid, K.E.; Bernhart, J.; Stehno, G.; Klosch, W.

1980-01-01

A versatile and automated secondary standard instrument has been designed for quick and accurate dose/rate measurement in a wide range of radiation intensity and quality (between 1 μR and 100 kR; 0.2 nC/kg - 20C/kg) for protection and therapy level dosimetry. The system is based on a series of secondary standard ionization chambers connected to a precision digital current integrator with microprocessor circuitry for data evaluation and control. Input of measurement parameters and calibration factors stored in an exchangeable memory chip provide computation of dose/rate values in the desired units. The ionization chambers provide excellent long-term stability and energy response and can be used with internal check sources to test validity of calibration. The system is a useful tool particularly for daily measurements in a secondary standard dosimetry laboratory or radiation therapy center. (H.K.)

Theory versus data: how to calculate R0?

Directory of Open Access Journals (Sweden)

Romulus Breban

2007-03-01

Full Text Available To predict the potential severity of outbreaks of infectious diseases such as SARS, HIV, TB and smallpox, a summary parameter, the basic reproduction number R(0, is generally calculated from a population-level model. R(0 specifies the average number of secondary infections caused by one infected individual during his/her entire infectious period at the start of an outbreak. R(0 is used to assess the severity of the outbreak, as well as the strength of the medical and/or behavioral interventions necessary for control. Conventionally, it is assumed that if R(0>1 the outbreak generates an epidemic, and if R(0<1 the outbreak becomes extinct. Here, we use computational and analytical methods to calculate the average number of secondary infections and to show that it does not necessarily represent an epidemic threshold parameter (as it has been generally assumed. Previously we have constructed a new type of individual-level model (ILM and linked it with a population-level model. Our ILM generates the same temporal incidence and prevalence patterns as the population-level model; we use our ILM to directly calculate the average number of secondary infections (i.e., R(0. Surprisingly, we find that this value of R(0 calculated from the ILM is very different from the epidemic threshold calculated from the population-level model. This occurs because many different individual-level processes can generate the same incidence and prevalence patterns. We show that obtaining R(0 from empirical contact tracing data collected by epidemiologists and using this R(0 as a threshold parameter for a population-level model could produce extremely misleading estimates of the infectiousness of the pathogen, the severity of an outbreak, and the strength of the medical and/or behavioral interventions necessary for control.

[Colonization of Porphyromonas endodontalis in primary and secondary endodontic infections].

Science.gov (United States)

Hong, Li; Hai, Ji; Yan-Yan, He; Shenghui, Yang; Benxiang, Hou

2015-02-01

This study aims to assess and compare the prevalence of Porphyromonas endodontalis (P. endodontalis) in root canals associated with primary and secondary endodontic infections by using 16s rDNA PCR and real-time fluorescence quantitative polymerase chain reaction (RTFQ-PCR). A total of 120 adult patients with one radiographically documented periapical lesion were included. Sixty teeth presented with primary endodontic infections and 60 with secondary endodontic infections requiring retreatment. P. endodontalis was identified by using 16s rDNA PCR techniques. The positive DNA expression of P. endodontalis in two types of infected root canals were quantitatively compared by using SYBR GREEN I RTFQ-PCR. The prevalence of P. endodontalis in the root canals with primary endodontic infections was significantly higher than that in root canals with secondary endodontic infections (P = 0.001). However, RTFQ-PCR results showed no significant difference in DNA expression quantities between the primary and secondary endodontic infections root canals (P = 0.303). P. endodontalis is more highly associated with root canals having primary endodontic infections, although P. endodontalis colonize in both root canals with primary and secondary chronic apical periodontitis.

One-year follow-up of neuropsychology, MRI, rCBF and glucose metabolism (rMRGlu) in cerebral microangiopathy

International Nuclear Information System (INIS)

Sabri, O.; Hellwig, D.; Schreckenberger, M.; Kaiser, H.-J.; Wagenknecht, G.; Setani, K.; Reinartz, P.; Zimny, M.; Buell, U.; Schneider, R.; Mull, M.; Ringelstein, E.-B.

2000-01-01

Background: MRI shows lacunar infarctions (LI), deep white matter lesions (DWML) and atrophy in cerebral microangiopathy, which is said to lead to vascular dementia. In a first trial series on 57 patients with confirmed pure cerebral microangiopathy (without concomitant macroangiopathy), neuropsychological impairment and (where present) brain atrophy correlated with decreased rCBF and rMRGlu. LI and DWML did not correlate with either neuropsychological impairment or decreased rCBF/rMRGlu. This study was done one year later to detect changes in any of the study parameters. Methods: 26 patients were re-examined for rCBF, rMRGlu, LI, DWML, atrophy and neuropsychological performance (7 cognitive, 3 mnestic, 4 attentiveness tests). Using a special head holder for exact repositioning, rCBF (SPECT) and rMRGlu (PET) were measured and imaged slice by slice. White matter/cortex were quantified using MRI-defined ROIs. Results: After one year the patients did not show significant decreases in rCBF or rMRGlu either in cortex or in white matter (p>0.05), nor did any patient show LI, DWML or atrophy changes on MRI. There were no significant neuropsychological decreases (p>0.05). (orig.) [de

File list: Oth.Neu.05.AllAg.Neural_progenitor_cells [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available Oth.Neu.05.AllAg.Neural_progenitor_cells mm9 TFs and others Neural Neural progenito...r cells SRX109472,SRX315274,SRX109471,SRX802060 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Oth.Neu.05.AllAg.Neural_progenitor_cells.bed ...

Creep of ex-service 0.5CrMoV steel at low strain rates

Czech Academy of Sciences Publication Activity Database

Kloc, Luboš

510-511, - (2009), s. 70-73 ISSN 0921-5093. [Creep 2008. Bayreuth, 04.05.2008-09.05.2008] R&D Projects: GA MŠk 1P05OC006 Institutional research plan: CEZ:AV0Z20410507 Keywords : Residual creep life * Low strain creep * Low alloy steel Subject RIV: JG - Metallurgy Impact factor: 1.901, year: 2009

Enhancement in electrical and magnetic properties with Ti-doping in Bi0.5La0.5Fe0.5Mn0.5O3

Science.gov (United States)

Singh, Rahul; Gupta, Prince Kumar; Kumar, Shiv; Joshi, Amish G.; Ghosh, A. K.; Patil, S.; Chatterjee, Sandip

2017-04-01

In this investigation, we have synthesized Bi0.5La0.5Fe0.5Mn0.5-xTixO3 (where x = 0 and 0.05) samples. The Rietveld refinement of X-ray diffraction (XRD) patterns shows that the systems crystallize in the orthorhombic phase with the Pnma space group. The observed Raman modes support the XRD results. The appearance of prominent A1-3 and weak E-2 modes in Bi0.5La0.5Fe0.5Mn0.45Ti0.05O3 indicates the presence of chemically more active Bi-O covalent bonds. Ferromagnetism of Bi0.5La0.5Fe0.5Mn0.5O3 is enhanced by Ti doping at the Mn-site, indicating that these particular samples might be interesting for device applications.

Synthesis and structural studies of Mg doped LiNi0.5Mn0.5O2 cathode materials for lithium-ion batteries

Science.gov (United States)

Murali, N.; Margarette, S. J.; Madhuri Sailaja, J.; Kondala Rao, V.; Himakar, P.; Kishore Babu, B.; Veeraiah, V.

2018-02-01

Layered Mg doped LiNi0.5Mn0.5O2 materials have been synthesized by sol-gel method. The physical properties of these materials were examined by XRD, FESEM and FT-IR studies. From XRD patterns, the phase formation of α-NaFeO2 layered structure with R\\bar 3m space group is confirmed. The surface morphology of the synthesized materials has been examined by FESEM analysis in which the average particle size is found to be about 2 - 2.5 µm. These materials show some changes in the local ion environment, as examined by FT-IR studies.

High energy storage property and breakdown strength of Bi{sub 0.5}(Na{sub 0.82}K{sub 0.18}){sub 0.5}TiO{sub 3} ceramics modified by (Al{sub 0.5}Nb{sub 0.5}){sup 4+} complex-ion

Energy Technology Data Exchange (ETDEWEB)

Zhao, Yangyang [Guangxi Key Laboratory of Information Materials, Guilin University of Electronic Technology, Guilin 541004 (China); Xu, Jiwen, E-mail: csuxjw@126.com [Guangxi Key Laboratory of Information Materials, Guilin University of Electronic Technology, Guilin 541004 (China); Guangxi Experiment Center of Information Science, Guilin 541004 (China); Yang, Ling; Zhou, Changrong [Guangxi Key Laboratory of Information Materials, Guilin University of Electronic Technology, Guilin 541004 (China); Guangxi Experiment Center of Information Science, Guilin 541004 (China); Lu, Xiaopeng; Yuan, Changlai; Li, Qingning; Chen, Guohua; Wang, Hua [Guangxi Key Laboratory of Information Materials, Guilin University of Electronic Technology, Guilin 541004 (China)

2016-05-05

The influence of B-site (Al{sub 0.5}Nb{sub 0.5}){sup 4+} complex-ion substitution on the phase transition, microstructure, dielectric, ferroelectric, and energy-storage properties of Bi{sub 0.5}(Na{sub 0.82}K{sub 0.18}){sub 0.5}Ti{sub 1–x}(Al{sub 0.5}Nb{sub 0.5}){sub x}O{sub 3} (BNKT-xAN) ceramics were systematically investigated. BNKT-xAN ceramics showed single-phase perovskite structure without an obvious phase transition after adding AN. Compact and uniform microstructure with almost the same grain morphology and size was obtained. The AN doping produced slimmer P-E loops and thus improved energy storage property. Meanwhile, the energy storage density increases drastically, and a maximum value of 1.41 J/cm{sup 3} at 105 kV/cm was achieved in BNKT-0.08AN through increasing greatly its breakdown strength with more AN content. The temperature dependence of dielectric constant and dielectric loss of BNKT-xAN ceramics illustrated the obvious relaxor phase transition characteristics. Low ionic conductivity and electronic conductivity indicated the BNKT-xAN ceramics have excellent dielectric properties. These results indicated that the BNKT-AN system may be a promising lead-free material for high energy storage density capacitor. - Highlights: • The (Al{sub 0.5}Nb{sub 0.5}){sup 4+} B-site complex ions were introduced into BNT-BKT system. • The P-E loops were pinched and the P{sub r} and E{sub c} were decreased by complex ions. • Impedance spectrum revealed excellent dielectric property of complex-ion modified BNT-BNK. • Breakdown strength of BNT-BKT was enhanced by complex ions. • The energy storage density was improved to 1.41 J/cm{sup 3} by complex ions.

Mechanism of blood pressure and R-R variability: insights from ganglion blockade in humans

Science.gov (United States)

Zhang, Rong; Iwasaki, Kenichi; Zuckerman, Julie H.; Behbehani, Khosrow; Crandall, Craig G.; Levine, Benjamin D.; Blomqvist, C. G. (Principal Investigator)

2002-01-01

Spontaneous blood pressure (BP) and R-R variability are used frequently as 'windows' into cardiovascular control mechanisms. However, the origin of these rhythmic fluctuations is not completely understood. In this study, with ganglion blockade, we evaluated the role of autonomic neural activity versus other 'non-neural' factors in the origin of BP and R-R variability in humans. Beat-to-beat BP, R-R interval and respiratory excursions were recorded in ten healthy subjects (aged 30 +/- 6 years) before and after ganglion blockade with trimethaphan. The spectral power of these variables was calculated in the very low (0.0078-0.05 Hz), low (0.05-0.15 Hz) and high (0.15-0.35 Hz) frequency ranges. The relationship between systolic BP and R-R variability was examined by cross-spectral analysis. After blockade, R-R variability was virtually abolished at all frequencies; however, respiration and high frequency BP variability remained unchanged. Very low and low frequency BP variability was reduced substantially by 84 and 69 %, respectively, but still persisted. Transfer function gain between systolic BP and R-R interval variability decreased by 92 and 88 % at low and high frequencies, respectively, while the phase changed from negative to positive values at the high frequencies. These data suggest that under supine resting conditions with spontaneous breathing: (1) R-R variability at all measured frequencies is predominantly controlled by autonomic neural activity; (2) BP variability at high frequencies (> 0.15 Hz) is mediated largely, if not exclusively, by mechanical effects of respiration on intrathoracic pressure and/or cardiac filling; (3) BP variability at very low and low frequencies (rhythmicity; and (4) the dynamic relationship between BP and R-R variability as quantified by transfer function analysis is determined predominantly by autonomic neural activity rather than other, non-neural factors.

Amino methylation of 2-R-6-R_1-imidazo-[2.1-B]-1.3.4-thiadiazole

International Nuclear Information System (INIS)

Saidov, D.K.; Rakhmonov, R.O.; Khodzhiboev, Yu.; Kukaniev, M.A.; Bandaev, S.

2015-01-01

Present article is devoted to amino methylation of 2-R-6-R_1-imidazo-[2.1-B]-1.3.4-thiadiazole. The reaction of new modifications of derivatives of imidazo-[2.1-B]-1.3.4-thiadiazoles-2-bromine-6-p-bromophenyl and 2-alkyl alkylene sulfonyl-6-phenyl imidazo--[2.1-B]-1.3.4-thiadiazole on Mannich with secondary and heterocyclic amines was studied.

Gd2O3 doped 0.82Bi0.5Na0.5TiO3–0.18Bi0.5K0.5TiO3 lead-free piezoelectric ceramics

International Nuclear Information System (INIS)

Fu, Peng; Xu, Zhijun; Chu, Ruiqing; Li, Wei; Wang, Wei; Liu, Yong

2012-01-01

Highlights: ► Gd 2 O 3 doped BNKT18 piezoelectric ceramics were designed and prepared. ► The electrical properties of the BNKT18 ceramics are improved with the addition of Gd 2 O 3 . ► The BNKT18 ceramics doped with 0.4 wt.% Gd 2 O 3 has better electrical properties. -- Abstract: Gd 2 O 3 (0–0.8 wt.%)-doped 0.82Bi 0.5 Na 0.5 TiO 3 –0.18Bi 0.5 K 0.5 TiO 3 (BNKT18) lead-free piezoelectric ceramics were synthesized by a conventional solid-state process. The effects of Gd 2 O 3 on the microstructure, the dielectric, ferroelectric and piezoelectric properties were investigated. X-ray diffraction (XRD) data shows that Gd 2 O 3 in an amount of 0.2–0.8 wt.% can diffuse into the lattice of BNKT18 ceramics and form a pure perovskite phase. Scanning electron microscope (SEM) images indicate that the grain size of BNKT18 ceramics decreases with the increase of Gd 2 O 3 content; in addition, all the modified ceramics have a clear grain boundary and a uniformly distributed grain size. At room temperature, the ferroelectric and piezoelectric properties of the BNKT18 ceramics have been improved with the addition of Gd 2 O 3 , and the BNKT18 ceramics doped with 0.4 wt.% Gd 2 O 3 have the highest piezoelectric constant (d 33 = 137 pC/N), highest relative dielectric constant (ε r = 1023) and lower dissipation factor (tan δ = 0.044) at a frequency of 10 kHz. The BNKT18 ceramics doped with 0.2 wt.% Gd 2 O 3 have the highest planar coupling factor (k p = 0.2463).

IFR code for secondary particle dynamics

International Nuclear Information System (INIS)

Teague, M.R.; Yu, S.S.

1985-01-01

A numerical simulation has been constructed to obtain a detailed, quantitative estimate of the electromagnetic fields and currents existing in the Advanced Test Accelerator under conditions of laser guiding. The code treats the secondary electrons by particle simulation and the beam dynamics by a time-dependent envelope model. The simulation gives a fully relativistic description of secondary electrons moving in self-consistent electromagnetic fields. The calculations are made using coordinates t, x, y, z for the electrons and t, ct-z, r for the axisymmetric electromagnetic fields and currents. Code results, showing in particular current enhancement effects, will be given

Let-7 and MicroRNA-148 Regulate Parathyroid Hormone Levels in Secondary Hyperparathyroidism.

Science.gov (United States)

Shilo, Vitali; Mor-Yosef Levi, Irit; Abel, Roy; Mihailović, Aleksandra; Wasserman, Gilad; Naveh-Many, Tally; Ben-Dov, Iddo Z

2017-08-01

Secondary hyperparathyroidism commonly complicates CKD and associates with morbidity and mortality. We profiled microRNA (miRNA) in parathyroid glands from experimental hyperparathyroidism models and patients receiving dialysis and studied the function of specific miRNAs. miRNA deep-sequencing showed that human and rodent parathyroids share similar profiles. Parathyroids from uremic and normal rats segregated on the basis of their miRNA expression profiles, and a similar finding was observed in humans. We identified parathyroid miRNAs that were dysregulated in experimental hyperparathyroidism, including miR-29, miR-21, miR-148, miR-30, and miR-141 (upregulated); and miR-10, miR-125, and miR-25 (downregulated). Inhibition of the abundant let-7 family increased parathyroid hormone (PTH) secretion in normal and uremic rats, as well as in mouse parathyroid organ cultures. Conversely, inhibition of the upregulated miR-148 family prevented the increase in serum PTH level in uremic rats and decreased levels of secreted PTH in parathyroid cultures. The evolutionary conservation of abundant miRNAs in normal parathyroid glands and the regulation of these miRNAs in secondary hyperparathyroidism indicates their importance for parathyroid function and the development of hyperparathyroidism. Specifically, let-7 and miR-148 antagonism modified PTH secretion in vivo and in vitro , implying roles for these specific miRNAs. These findings may be utilized for therapeutic interventions aimed at altering PTH expression in diseases such as osteoporosis and secondary hyperparathyroidism. Copyright © 2017 by the American Society of Nephrology.

High level bacterial contamination of secondary school students' mobile phones.

Science.gov (United States)

Kõljalg, Siiri; Mändar, Rando; Sõber, Tiina; Rööp, Tiiu; Mändar, Reet

2017-06-01

While contamination of mobile phones in the hospital has been found to be common in several studies, little information about bacterial abundance on phones used in the community is available. Our aim was to quantitatively determine the bacterial contamination of secondary school students' mobile phones. Altogether 27 mobile phones were studied. The contact plate method and microbial identification using MALDI-TOF mass spectrometer were used for culture studies. Quantitative PCR reaction for detection of universal 16S rRNA, Enterococcus faecalis 16S rRNA and Escherichia coli allantoin permease were performed, and the presence of tetracycline ( tet A, tet B, tet M), erythromycin ( erm B) and sulphonamide ( sul 1) resistance genes was assessed. We found a high median bacterial count on secondary school students' mobile phones (10.5 CFU/cm 2 ) and a median of 17,032 bacterial 16S rRNA gene copies per phone. Potentially pathogenic microbes ( Staphylococcus aureus , Acinetobacter spp. , Pseudomonas spp., Bacillus cereus and Neisseria flavescens ) were found among dominant microbes more often on phones with higher percentage of E. faecalis in total bacterial 16S rRNA. No differences in contamination level or dominating bacterial species between phone owner's gender and between phone types (touch screen/keypad) were found. No antibiotic resistance genes were detected on mobile phone surfaces. Quantitative study methods revealed high level bacterial contamination of secondary school students' mobile phones.

Preparation of La{sub 0.75}Sr{sub 0.25}Cr{sub 0.5}Mn{sub 0.5}O{sub 3-{delta}} fine powders by carbonate coprecipitation for solid oxide fuel cells

Energy Technology Data Exchange (ETDEWEB)

Ha, Sang Bu; Cho, Pyeong-Seok; Cho, Yoon Ho; Lee, Dokyol; Lee, Jong-Heun [Department of Materials Science and Engineering, Korea University, Anam-dong, Sungbuk-ku, Seoul 136-713 (Korea)

2010-01-01

A range of La{sub 0.75}Sr{sub 0.25}Cr{sub 0.5}Mn{sub 0.5}O{sub 3-{delta}} (LSCM) powders is prepared by the carbonate coprecipitation method for use as anodes in solid oxide fuel cells. The supersaturation ratio (R = [(NH{sub 4}){sub 2}CO{sub 3}]/([La{sup 3+}] + [Sr{sup 2+}] + [Cr{sup 3+}] + [Mn{sup 2+}])) during the coprecipitation determines the relative compositions of La, Sr, Cr, and Mn. The composition of the precursor approaches the stoichiometric one at the supersaturation range of 4 {<=} R {<=} 12.5, whereas Sr and Mn components are deficient at R < 4 and excessive at R = 25. The fine and phase-pure LSCM powders are prepared by heat treatment at very low temperature (1000 C) at R = 7.5 and 12.5. By contrast, the solid-state reaction requires a higher heat-treatment temperature (1400 C). The catalytic activity of the LSCM electrodes is enhanced by using carbonate-derived powders to manipulate the electrode microstructures. (author)

Optical Photometry and X-Ray Monitoring of the ``Cool Algol'' BD +05°706: Determination of the Physical Properties

Science.gov (United States)

Torres, Guillermo; Mader, Jeff A.; Marschall, Laurence A.; Neuhäuser, Ralph; Duffy, Alaine S.

2003-06-01

We present new photometric observations in the BVRI bands of the double-lined eclipsing binary BD +05°706 conducted over three observing seasons, as well as new X-ray observations obtained with ROSAT covering a full orbital cycle (P=18.9 days). A detailed light-curve analysis of the optical data shows the system to be semidetached, confirming indications from an earlier analysis by Torres et al. (published in 1998), with the less massive and cooler star filling its Roche lobe. The system is a member of the rare class of cool Algol systems, which are different from the ``classical'' Algol systems in that the mass-gaining component is also a late-type star rather than a B- or A-type star. By combining the new photometry with a reanalysis of the spectroscopic observations reported by Torres et al., we derive accurate absolute masses for the components of M1=2.633+/-0.028 Msolar and M2=0.5412+/-0.0093 Msolar, radii of R1=7.55+/-0.20 Rsolar and R2=11.02+/-0.21 Rsolar, as well as effective temperatures of 5000+/-100 and 4640+/-150 K, for the primary and secondary, respectively. There are obvious signs of activity (spottedness) in the optical light curve of the binary. Our X-ray light curve clearly shows the primary eclipse but not the secondary eclipse, suggesting that the primary star is the dominant source of the activity in the system. The depth and duration of the eclipse allow us to infer some of the properties of the X-ray-emitting region around that star.

Measurement of the $B^{+}$ and $B^{0}$ lifetimes and search for CP(T) violation using reconstructed secondary vertices

CERN Document Server

Abbiendi, G.; Alexander, G.; Allison, John; Altekamp, N.; Anderson, K.J.; Anderson, S.; Arcelli, S.; Asai, S.; Ashby, S.F.; Axen, D.; Azuelos, G.; Ball, A.H.; Barberio, E.; Barlow, Roger J.; Bartoldus, R.; Batley, J.R.; Baumann, S.; Bechtluft, J.; Behnke, T.; Bell, Kenneth Watson; Bella, G.; Bellerive, A.; Bentvelsen, S.; Bethke, S.; Betts, S.; Biebel, O.; Biguzzi, A.; Bird, S.D.; Blobel, V.; Bloodworth, I.J.; Bock, P.; Bohme, J.; Bonacorsi, D.; Boutemeur, M.; Braibant, S.; Bright-Thomas, P.; Brigliadori, L.; Brown, Robert M.; Burckhart, H.J.; Capiluppi, P.; Carnegie, R.K.; Carter, A.A.; Carter, J.R.; Chang, C.Y.; Charlton, David G.; Chrisman, D.; Ciocca, C.; Clarke, P.E.L.; Clay, E.; Cohen, I.; Conboy, J.E.; Cooke, O.C.; Couyoumtzelis, C.; Coxe, R.L.; Cuffiani, M.; Dado, S.; Dallavalle, G.Marco; Davis, R.; De Jong, S.; de Roeck, A.; Dervan, P.; Desch, K.; Dienes, B.; Dixit, M.S.; Dubbert, J.; Duchovni, E.; Duckeck, G.; Duerdoth, I.P.; Eatough, D.; Estabrooks, P.G.; Etzion, E.; Fabbri, F.; Fanti, M.; Faust, A.A.; Fiedler, F.; Fierro, M.; Fleck, I.; Folman, R.; Furtjes, A.; Futyan, D.I.; Gagnon, P.; Gary, J.W.; Gascon, J.; Gascon-Shotkin, S.M.; Gaycken, G.; Geich-Gimbel, C.; Giacomelli, G.; Giacomelli, P.; Gibson, V.; Gibson, W.R.; Gingrich, D.M.; Glenzinski, D.; Goldberg, J.; Gorn, W.; Grandi, C.; Graham, K.; Gross, E.; Grunhaus, J.; Gruwe, M.; Hanson, G.G.; Hansroul, M.; Hapke, M.; Harder, K.; Harel, A.; Hargrove, C.K.; Hartmann, C.; Hauschild, M.; Hawkes, C.M.; Hawkings, R.; Hemingway, R.J.; Herndon, M.; Herten, G.; Heuer, R.D.; Hildreth, M.D.; Hill, J.C.; Hobson, P.R.; Hoch, M.; Hocker, James Andrew; Hoffman, Kara Dion; Homer, R.J.; Honma, A.K.; Horvath, D.; Hossain, K.R.; Howard, R.; Huntemeyer, P.; Igo-Kemenes, P.; Imrie, D.C.; Ishii, K.; Jacob, F.R.; Jawahery, A.; Jeremie, H.; Jimack, M.; Jones, C.R.; Jovanovic, P.; Junk, T.R.; Karlen, D.; Kartvelishvili, V.; Kawagoe, K.; Kawamoto, T.; Kayal, P.I.; Keeler, R.K.; Kellogg, R.G.; Kennedy, B.W.; Kim, D.H.; Klier, A.; Kluth, S.; Kobayashi, T.; Kobel, M.; Koetke, D.S.; Kokott, T.P.; Kolrep, M.; Komamiya, S.; Kowalewski, Robert V.; Kress, T.; Krieger, P.; von Krogh, J.; Kuhl, T.; Kyberd, P.; Lafferty, G.D.; Landsman, H.; Lanske, D.; Lauber, J.; Lautenschlager, S.R.; Lawson, I.; Layter, J.G.; Lazic, D.; Lee, A.M.; Lellouch, D.; Letts, J.; Levinson, L.; Liebisch, R.; List, B.; Littlewood, C.; Lloyd, A.W.; Lloyd, S.L.; Loebinger, F.K.; Long, G.D.; Losty, M.J.; Ludwig, J.; Lui, D.; Macchiolo, A.; Macpherson, A.; Mader, W.; Mannelli, M.; Marcellini, S.; Markopoulos, C.; Martin, A.J.; Martin, J.P.; Martinez, G.; Mashimo, T.; Mattig, Peter; McDonald, W.John; McKenna, J.; Mckigney, E.A.; McMahon, T.J.; McPherson, R.A.; Meijers, F.; Menke, S.; Merritt, F.S.; Mes, H.; Meyer, J.; Michelini, A.; Mihara, S.; Mikenberg, G.; Miller, D.J.; Mir, R.; Mohr, W.; Montanari, A.; Mori, T.; Nagai, K.; Nakamura, I.; Neal, H.A.; Nellen, B.; Nisius, R.; O'Neale, S.W.; Oakham, F.G.; Odorici, F.; Ogren, H.O.; Oreglia, M.J.; Orito, S.; Palinkas, J.; Pasztor, G.; Pater, J.R.; Patrick, G.N.; Patt, J.; Perez-Ochoa, R.; Petzold, S.; Pfeifenschneider, P.; Pilcher, J.E.; Pinfold, J.; Plane, David E.; Poffenberger, P.; Polok, J.; Przybycien, M.; Rembser, C.; Rick, H.; Robertson, S.; Robins, S.A.; Rodning, N.; Roney, J.M.; Roscoe, K.; Rossi, A.M.; Rozen, Y.; Runge, K.; Runolfsson, O.; Rust, D.R.; Sachs, K.; Saeki, T.; Sahr, O.; Sang, W.M.; Sarkisian, E.K.G.; Sbarra, C.; Schaile, A.D.; Schaile, O.; Scharf, F.; Scharff-Hansen, P.; Schieck, J.; Schmitt, B.; Schmitt, S.; Schoning, A.; Schroder, Matthias; Schumacher, M.; Schwick, C.; Scott, W.G.; Seuster, R.; Shears, T.G.; Shen, B.C.; Shepherd-Themistocleous, C.H.; Sherwood, P.; Siroli, G.P.; Sittler, A.; Skuja, A.; Smith, A.M.; Snow, G.A.; Sobie, R.; Soldner-Rembold, S.; Spagnolo, S.; Sproston, M.; Stahl, A.; Stephens, K.; Steuerer, J.; Stoll, K.; Strom, David M.; Strohmer, R.; Surrow, B.; Talbot, S.D.; Tanaka, S.; Taras, P.; Tarem, S.; Teuscher, R.; Thiergen, M.; Thomas, J.; Thomson, M.A.; von Torne, E.; Torrence, E.; Towers, S.; Trigger, I.; Trocsanyi, Z.; Tsur, E.; Turcot, A.S.; Turner-Watson, M.F.; Ueda, I.; Van Kooten, Rick J.; Vannerem, P.; Verzocchi, M.; Voss, H.; Wackerle, F.; Wagner, A.; Ward, C.P.; Ward, D.R.; Watkins, P.M.; Watson, A.T.; Watson, N.K.; Wells, P.S.; Wermes, N.; White, J.S.; Wilson, G.W.; Wilson, J.A.; Wyatt, T.R.; Yamashita, S.; Yekutieli, G.; Zacek, V.; Zer-Zion, D.

2000-01-01

The lifetimes of the B+ and B0 mesons, and their ratio, have been measured in the OPAL experiment using 2.4 million hadronic Z0 decays recorded at LEP. Z0 -> b bbar decays were tagged using displaced secondary vertices and high momentum electrons and muons. The lifetimes were then measured using well-reconstructed charged and neutral secondary vertices selected in this tagged data sample. The results are tau(B+) = 1.643 +- 0.037 +- 0.025 ps tau(B0) = 1.523 +- 0.057 +- 0.053 ps ratio tau(B+)/tau(B0) = 1.079 +- 0.064 +- 0.041 where in each case the first error is statistical and the second systematic. A larger data sample of 3.1 million hadronic Z0 decays has been used to search for CP and CPT violating effects by comparison of inclusive b and bbar hadron decays. No evidence for such effects is seen. The CP violation parameter Re(epsilon_B) is measured to be Re(epsilon_B) = 0.001 +- 0.014 +- 0.003 and the fractional difference between b and bbar hadron lifetimes is measured to be -0.001 +- 0.012 +- 0.008

Association of Corynebacterium pseudotuberculosis recombinant proteins rCP09720 or rCP01850 with rPLD as immunogens in caseous lymphadenitis immunoprophylaxis.

Science.gov (United States)

Silva, Mara Thais de Oliveira; Bezerra, Francisco Silvestre Brilhante; de Pinho, Rodrigo Barros; Begnini, Karine Rech; Seixas, Fabiana Kommling; Collares, Tiago; Portela, Ricardo Dias; Azevedo, Vasco; Dellagostin, Odir; Borsuk, Sibele

2018-01-02

Caseous lymphadenitis (CLA) is a chronic disease responsible for significant economic losses in sheep and goat breeding worldwide. The treatment for this disease is not effective, and an intense vaccination schedule would be the best control strategy. In this study, we evaluated the associations of rCP09720 or rCP01850 proteins from Corynebacterium pseudotuberculosis with recombinant exotoxin phospholipase D (rPLD) as subunit vaccines in mice. Four experimental groups (10 animals each) were immunized with a sterile 0.9% saline solution (G1), rPLD (G2), rPLD + rCP09720 (G3), and rPLD + rCP01850 (G4). The mice received two doses of each vaccine at a 21-day interval and were challenged 21 days after the last immunization. The animals were evaluated daily for 40 days after the challenge, and mortality rate was recorded. The total IgG production level increased significantly in the experimental groups on day 42 after the first vaccination. Similarly, higher levels of specific IgG2a were observed in experimental groups G2, G3, and G4 compared to the IgG1 levels on day 42. G4 showed a significant (p < .05) humoral response against both antigens of the antigenic formulations. The cellular immune response induced by immunization was characterized by a significant (p < .05) production of interferon-γ compared to that in the control, while the concentrations of interleukin (IL)-4 and IL-12 were not significant in any group. A significant increase of tumor necrosis factor was observed only in G4. The survival rates after the challenge were 30% (rPLD), 40% (rPLD + rCP09720), and 50% (rPLD + rCP01850). Thus, the association of rCP01850 with rPLD resulted in the best protection against the challenge with C. pseudotuberculosis and induced a more intense type 1 T-helper cell immune response. Copyright © 2017 Elsevier Ltd. All rights reserved.

Blood pressure variability in children with primary vs secondary hypertension.

Science.gov (United States)

Leisman, Daniel; Meyers, Melissa; Schnall, Jeremy; Chorny, Nataliya; Frank, Rachel; Infante, Lulette; Sethna, Christine B

2014-06-01

Increased blood pressure variability (BPV) is correlated with adverse cardiovascular (CV) events in adults. However, there has been limited research on its effect in the pediatric population. Additionally, BPV differences between primary and secondary hypertension (HTN) are not known. Children with primary and secondary HTN underwent 24-hour ambulatory blood pressure monitoring and echocardiography studies. BPV measures of standard deviation (SD), average real variability (ARV), and range were calculated for the 24-hour, daytime, and nighttime periods. Seventy-four patients (median age, 13.5 years; 74% boys) were examined, 40 of whom had primary HTN. Body mass index z score and age were independent predictors of systolic ARV (R(2) =0.14) and SD (R(2) =0.39). There were no statistically significant differences in overall or wake period BPV measures between secondary or primary HTN groups, but sleep period diastolic SD was significantly greater in the secondary HTN group (9.26±3.8 vs 7.1±2.8, P=.039). On multiple regression analysis, secondary HTN was associated with increased sleep period diastolic SD (P=.025). No metrics of BPV in the overall, wake, and sleep periods were found to be significantly associated with left ventricular hypertrophy (LVH). The results of this study do not show a strong relationship between overall or wake BPV with primary vs secondary HTN, but the association of secondary HTN with sleep period diastolic BPV deserves further exploration. Contrary to expectation, the findings of this study failed to indicate a relationship between BPV and LVH for all patients as well for primary hypertensive and secondary hypertensive patients. ©2014 Wiley Periodicals, Inc.

Epigenetic Methylation of Parathyroid CaR and VDR Promoters in Experimental Secondary Hyperparathyroidism

DEFF Research Database (Denmark)

Hofman-Bang, Jacob; Gravesen, Eva; Olgaard, Klaus

2012-01-01

R in parathyroid cultures decreases rapidly. Methylation of promoter regions is often detected during epigenetic downregulation of gene expression. Therefore, using an experimental rat model, we examined changes in methylation levels of parathyroid CaR and VDR promoters in vivo and in vitro. Methods. Uremia...... of parathyroid CaR and VDR genes were found. Thus, epigenetic methylation of these promoters does not explain decreased parathyroid expression of CaR and VDR genes in uremic s-HPT....

Rietveld refinement, impedance spectroscopy and magnetic properties of Bi{sub 0.8}Sr{sub 0.2}FeO{sub 3} substituted Na{sub 0.5}Bi{sub 0.5}TiO{sub 3} ceramics

Energy Technology Data Exchange (ETDEWEB)

Kumari, Rekha [Department of Applied Physics, Guru Jambheshwar University of Science & Technology, Hisar 125001, Haryana (India); Ahlawat, Neetu, E-mail: neetugju@yahoo.co.in [Department of Applied Physics, Guru Jambheshwar University of Science & Technology, Hisar 125001, Haryana (India); Agarwal, Ashish; Sanghi, Sujata [Department of Applied Physics, Guru Jambheshwar University of Science & Technology, Hisar 125001, Haryana (India); Sindhu, Monica [Department of Physics, MKJK College, Rohtak 124001, Haryana (India); Ahlawat, Navneet [Matu Ram Institute of Engineering and Management, Rohtak 124001, Haryana (India)

2016-09-15

We herein presented the investigation on the structural, electrical and magnetic properties of (1−x)(Na{sub 0.5}Bi{sub 0.5}TiO{sub 3})–x(Bi{sub 0.8}Sr{sub 0.2}FeO{sub 3}) polycrystalline ceramic samples, with x=0.1, 0.3, 0.5 and 0.7. These samples were prepared by conventional solid state reaction method and the crystalline phase of prepared ceramics was identified with the help of X-ray diffraction pattern. Rietveld analysis of the obtained XRD data confirmed that all the synthesized samples adopt the rhombohedral crystal structure with R3c space group. Impedance spectroscopic measurements were performed on all the compositions in the frequency range 10 Hz–5 MHz to probe the electrical microstructure of polycrystalline (1−x)(Na{sub 0.5}Bi{sub 0.5}TiO{sub 3})–x(Bi{sub 0.8}Sr{sub 0.2}FeO{sub 3}) ceramics, which changes significantly as a function of x (content of BSFO). A significant increase in dielectric constant has been observed with increase in BSFO concentration, which was attributed to enhancement of oxygen vacancies. Detailed study of impedance complex plane plots revealed the presence of non-Debye type relaxation for all the prepared systems and enabled us to separate the contribution from grains and grain boundaries. Equivalent circuit model (R{sub g}CPE{sub g})(R{sub gb}CPE{sub gb})(R{sub e}CPE{sub e}) was employed to explain the impedance data for all the prepared samples. The activation energies obtained from electric modulus as well as dc conductivity increase with increase in BSFO content, which approaches the value 1 eV and indicates an Arrehenius type thermally activated process. Remnant magnetization (M{sub r}) and coercive field (H{sub c}) are found to be increase with BSFO concentration. - Highlights: • (1−x)NBT–xBSFO (x=0.1, 0.3, 0.5, 0.7) ceramics were prepared. • There is no change in crystal structure. • These can be used as data storage materials.

Health survey and assessment of the polymorphisms BRCA1/P871L, BRCA1/Q356R, and BRCA2/N372H in female gas station workers in Rio de Janeiro.

Science.gov (United States)

Silvestre, Rafaele T; Delmonico, Lucas; Bravo, Maryah; Santiago, Fábio; Scherrer, Luciano R; Moreira, Aline Dos Santos; Tabalipa, Marianne; Otero, Ubirani; Ornellas, Maria Helena F; Alves, Gilda

2017-12-01

Gas station workers are exposed to chemicals known to be carcinogenic, especially benzene. The objective was to analyze the health problems of female gas station workers by means of sociodemographic and clinical questionnaires, and laboratorial exams. We performed the genotyping of the polymorphisms BRCA1/P871L and BRCA1/Q356R by Polymerase Chain Reaction-Restriction Fragment Length Polymorphism, and of variant allele BRCA2/N372H through direct sequencing. The female workers showed a higher concentration of monocytes (P = 0.039); a greater number of spontaneous abortions (P = 0.025, OR = 4.977, 95% CI = 1.135-30.669); higher tobacco consumption (P = 0.013); and higher alcohol consumption (P = 0.05). The statistical analysis of the polymorphisms associated with the variables monocyte concentration and miscarriage number did not reveal a significant relationship, and smoking and spontaneous abortion were not statistically associated either. Environ. Mol. Mutagen. 58:730-734, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

Hydrothermal synthesis of a photovoltaic material based on CuIn0.5Ga0.5Se2

Science.gov (United States)

Castellanos Báez, Y. T.; Fuquen Peña, D. A.; Gómez-Cuaspud, J. A.; Vera-López, E.; Pineda-Triana, Y.

2017-12-01

The present work report, the synthesis and characterization of the CuIn0.5Ga0.5Se2 system (abbreviated CIGS), by the implementation of a hydrothermal route, in order to obtain a solid with appropriate properties in terms of surface, morphological and texture properties for potential applications in the design of photovoltaic cells. The synthesis was carried out using the corresponding stoichiometric quantities (Cu:In:Ga:Se 1:0.5:0.5:2), which were mixed in a Teflon vessel under stirring conditions. The homogeneous solution was treated in a steel autoclave at 300°C for 72 hours at the end of which the resulting material was characterized by X-Ray Diffraction (XRD) and Rietveld refinement. The results of the structural characterization allowed to confirm the obtaining of a chalcopyrite type structure, with a I-42 d (122) structure and cell parameters a=0.570, b=0.570, c=1.140nm, α=90, β=90, γ=90° oriented along (1 0 4) facet, detecting the presence of a secondary phases, related with CuInSe and CuIn metallic selenides, derived from synthesis process. The structural refinement allowing to validate the obtaining of a nanometric crystalline material (10-20nm) for potential applications in field of photovoltaic technology.

Secondary osteons scale allometrically in mammalian humerus and femur.

Science.gov (United States)

Felder, A A; Phillips, C; Cornish, H; Cooke, M; Hutchinson, J R; Doube, M

2017-11-01

Intra-cortical bone remodelling is a cell-driven process that replaces existing bone tissue with new bone tissue in the bone cortex, leaving behind histological features called secondary osteons. While the scaling of bone dimensions on a macroscopic scale is well known, less is known about how the spatial dimensions of secondary osteons vary in relation to the adult body size of the species. We measured the cross-sectional area of individual intact secondary osteons and their central Haversian canals in transverse sections from 40 stylopodal bones of 39 mammalian species (body mass 0.3-21 000 kg). Scaling analysis of our data shows that mean osteonal resorption area (negative allometry, exponent 0.23, R 2  0.54, p <0.005) and Haversian canal area (negative allometry, exponent 0.31, R 2  0.45, p <0.005) are significantly related to body mass, independent of phylogeny. This study is the most comprehensive of its kind to date, and allows us to describe overall trends in the scaling behaviour of secondary osteon dimensions, supporting the inference that the osteonal resorption area may be limited by the need to avoid fracture in smaller mammalian species, but the need to maintain osteocyte viability in larger mammalian species.

Dicty_cDB: Contig-U04444-1 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available 5004 ) sat05c04.y1 Gm-c1036 Glycine max cDNA clone SOYBE... 52 0.025 1 ( BU894001 ) P085G03 Populus petioles cDNA library Popul...s cDNA, RIKEN full-l... 52 0.025 1 ( CF870513 ) tric023xm17.b1 T.reesei mycelial culture, Versio...n... 52 0.025 1 ( CF869757 ) tric020xf11.b1 T.reesei mycelial culture, Version... 52 0.025 1 ( CF867854 ) tric012xm19.b1 T.re...esei mycelial culture, Version... 52 0.025 1 ( CF867232 ) tric010xg18.b1 T.re...esei mycelial culture, Version 3 ... 52 0.025 1 ( CB899903 ) tric020xf11 T.reesei mycelial culture

Secondary prophylaxis with rFVIIa in hemophilia and inhibitors: Recommendations from an Experts Committee from Argentina Profilaxis secundaria con rFVIIa en pacientes con hemofilia e inhibidores: Recomendaciones de un comité de expertos de Argentina

Directory of Open Access Journals (Sweden)

Raúl Pérez Bianco

2010-06-01

Full Text Available Secondary prophylaxis with rFVIIa has been the subject of several publications in the past few years. However, there is no general consensus on how this treatment should be put into practice, as publications have been very heterogeneous in the dosing schedule they report. Furthermore, the mechanism of action of rFVIIa and its short half life have been used as arguments against its role in prophylaxis. There have been a series of recent publications that show that rFVIIa can traffic through the intact endothelium and be stored in the subendothelium of several organs for a prolonged period of time. In order to consensuate the role of rFVIIa in prophylaxis, a group of experts from Argentina, resumed available information regarding pharmacology and clinical experience with this treatment, and developed a series of recommendations to use this drug in the prophylaxis setting.La profilaxis secundaria con factor VII activado recombinante (rFVIIa ha sido objeto de varias publicaciones en los últimos años. Sin embargo, no existe un consenso general sobre cómo este tratamiento debe ser puesto en práctica, dado que las publicaciones han sido muy heterogéneas respecto del régimen de dosificación que publican. Además, el mecanismo de acción del rFVIIa y su vida media corta se han utilizado como argumentos en contra de su papel en la profilaxis. Ha habido una serie de publicaciones recientes que muestran que el rFVIIa puede atravesar el endotelio intacto y almacenarse en el subendotelio de diversos órganos durante un período prolongado de tiempo. Con el fin de consensuar el papel de rFVIIa en la profilaxis, un grupo de expertos de Argentina, ha recopilado la información disponible sobre la farmacología y la experiencia clínica con este tratamiento, y desarrolló una serie de recomendaciones para utilizar este fármaco en el ámbito de profilaxis.

Bloqueio do plexo lombar pela via posterior para analgesia pós-operatória em artroplastia total do quadril: estudo comparativo entre Bupivacaína a 0,5% com Epinefrina e Ropivacaína a 0,5% Bloqueo del plexo lumbar por la vía posterior para analgesia postoperatoria en artroplastia total de la cadera: estudio comparativo entre Bupivacaína a 0,5% con Epinefrina y Ropivacaína a 0,5% Posterior lumbar plexus block in postoperative analgesia for total hip arthroplasty: a comparative study between 0.5% Bupivacaine with Epinephrine and 0.5% Ropivacaine

Directory of Open Access Journals (Sweden)

Leonardo Teixeira Domingues Duarte

2009-06-01

Full Text Available JUSTIFICATIVA E OBJETIVOS: O bloqueio do plexo lombar pela via posterior promove analgesia pós-operatória efetiva na artroplastia total do quadril. Ropivacaína e bupivacaína não apresentaram qualquer diferença na eficácia analgésica em diferentes bloqueios de nervos periféricos. O objetivo deste estudo foi comparar a eficácia da analgesia pós-operatória resultante da administração em dose única da bupivacaína a 0,5% ou da ropivacaína a 0,5% no bloqueio do plexo lombar pela via posterior na artroplastia total do quadril. MÉTODO: Trinta e sete pacientes foram alocados aleatoriamente em dois grupos, segundo o anestésico local utilizado no bloqueio: Grupo B - bupivacaína a 0,5% com epinefrina 1:200.000 ou Grupo R - ropivacaína a 0,5%. Durante o período pós-operatório, os escores de dor e o consumo de morfina na analgesia controlada pelo paciente foram comparados entre os grupos. O sangramento durante a operação e a incidência de efeitos adversos e de complicações também foram comparados. RESULTADOS: Apesar dos escores de dor terem sido menores no Grupo R 8, 12 e 24 horas após o bloqueio, essas diferenças não foram clinicamente significativas. Regressão linear múltipla não identificou o anestésico local como variável independente. Não houve diferença no consumo de morfina, no sangramento intraoperatório e na incidência de complicações e efeitos adversos entre os dois grupos. CONCLUSÕES: A bupivacaína a 0,5% e a ropivacaína a 0,5% produziram alívio eficaz e prolongado da dor pós-operatória após artroplastia total do quadril, sem diferença clínica, quando doses equivalentes foram administradas no bloqueio do plexo lombar pela via posterior.JUSTIFICATIVA Y OBJETIVOS: El bloqueo del plexo lumbar por la vía posterior, genera una analgesia postoperatoria efectiva en la artroplastia total de la cadera. La ropivacaína y la bupivacaína no arrojaron ninguna diferencia en la eficacia analgésica en

A mixed iron-manganese based pyrophosphate cathode, Na2Fe0.5Mn0.5P2O7, for rechargeable sodium ion batteries.

Science.gov (United States)

Shakoor, Rana A; Park, Chan Sun; Raja, Arsalan A; Shin, Jaeho; Kahraman, Ramazan

2016-02-07

The development of secondary batteries based on abundant and cheap elements is vital. Among various alternatives to conventional lithium-ion batteries, sodium-ion batteries (SIBs) are promising due to the abundant resources and low cost of sodium. While there are many challenges associated with the SIB system, cathode is an important factor in determining the electrochemical performance of this battery system. Accordingly, ongoing research in the field of SIBs is inclined towards the development of safe, cost effective cathode materials having improved performance. In particular, pyrophosphate cathodes have recently demonstrated decent electrochemical performance and thermal stability. Herein, we report the synthesis, electrochemical properties, and thermal behavior of a novel Na2Fe0.5Mn0.5P2O7 cathode for SIBs. The material was synthesized through a solid state process. The structural analysis reveals that the mixed substitution of manganese and iron has resulted in a triclinic crystal structure (P1[combining macron] space group). Galvanostatic charge/discharge measurements indicate that Na2Fe0.5Mn0.5P2O7 is electrochemically active with a reversible capacity of ∼80 mA h g(-1) at a C/20 rate with an average redox potential of 3.2 V. (vs. Na/Na(+)). It is noticed that 84% of initial capacity is preserved over 90 cycles showing promising cyclability. It is also noticed that the rate capability of Na2Fe0.5Mn0.5P2O7 is better than Na2MnP2O7. Ex situ and CV analyses indicate that Na2Fe0.5Mn0.5P2O7 undergoes a single phase reaction rather than a biphasic reaction due to different Na coordination environment and different Na site occupancy when compared to other pyrophosphate materials (Na2FeP2O7 and Na2MnP2O7). Thermogravimetric analysis (25-550 °C) confirms good thermal stability of Na2Fe0.5Mn0.5P2O7 with only 2% weight loss. Owing to promising electrochemical properties and decent thermal stability, Na2Fe0.5Mn0.5P2O7, can be an attractive cathode for SIBs.

One-year follow-up of neuropsychology, MRI, rCBF and glucose metabolism (rMRGlu) in cerebral microangiopathy

Energy Technology Data Exchange (ETDEWEB)

Sabri, O.; Hellwig, D.; Schreckenberger, M.; Kaiser, H.-J.; Wagenknecht, G.; Setani, K.; Reinartz, P.; Zimny, M.; Buell, U. [Department of Nuclear Medicine, Technische Univ. Aachen (Germany); Schneider, R. [Department of Neurology, Technische Univ. Aachen (Germany); Mull, M. [Department of Neuroradiology, Technische Univ. Aachen (Germany); Ringelstein, E.-B. [Department of Neurology, Muenster Univ. (Germany)

2000-07-01

Background: MRI shows lacunar infarctions (LI), deep white matter lesions (DWML) and atrophy in cerebral microangiopathy, which is said to lead to vascular dementia. In a first trial series on 57 patients with confirmed pure cerebral microangiopathy (without concomitant macroangiopathy), neuropsychological impairment and (where present) brain atrophy correlated with decreased rCBF and rMRGlu. LI and DWML did not correlate with either neuropsychological impairment or decreased rCBF/rMRGlu. This study was done one year later to detect changes in any of the study parameters. Methods: 26 patients were re-examined for rCBF, rMRGlu, LI, DWML, atrophy and neuropsychological performance (7 cognitive, 3 mnestic, 4 attentiveness tests). Using a special head holder for exact repositioning, rCBF (SPECT) and rMRGlu (PET) were measured and imaged slice by slice. White matter/cortex were quantified using MRI-defined ROIs. Results: After one year the patients did not show significant decreases in rCBF or rMRGlu either in cortex or in white matter (p>0.05), nor did any patient show LI, DWML or atrophy changes on MRI. There were no significant neuropsychological decreases (p>0.05). (orig.) [German] Ziel: In der MRT zeigen sich bei zerebraler Mikroangiopathie (ZMA) lakunaere Infarkte (LI), Deep White Matter Lesions (DWML) und Atrophie (Atr). Die sogenannte vaskulaere Demenz wurde dabei hauptsaechlich auf die Laesionen der weissen Substanz zurueckgefuehrt. In einer ersten Untersuchungsreihe waren bei 57 Patienten mit gesicherter ZMA nur neuropsychologische Defizite (Nps) und, falls vorhanden, Atr als Grundlage fuer erniedrigte rCBF/rMRGlu-Werte zu eruieren, jedoch nicht LI/DWML. Es sollte geklaert werden, ob sich im Verlauf der Erkrankung nach einem Jahr Veraenderungen dieser Parameter ergeben. Methode: 26 Patienten wurden nach einem Jahr erneut neuropsychologisch untersucht (7 kognitive, 3 mnestrische, 4 Aufmerksamkeitstests). Mittels eines speziellen Kopfhalterungssystems wurden in

Complex impedance techniques and some properties of Mn sub 0.5 Zn sub 0.5 Fe sub 2 O sub 4 ferrite

International Nuclear Information System (INIS)

Ahmad Nazlim Yusoff; Mustaffa Abdullah

1995-01-01

Complex impedances (Z-axes = Z' - jZ ) of a standard parallel R-C circuit and a Mn sub 0.5 Zn sub 0.5 Fe sub 2 O sub 4 ferrite sample at 300 K have been measured in the frequency range 1 Hz to 10 MHz by a technique of phase shift. For comparison, the impedances of both systems were also measured using Schlumberger HF 1255 frequency response analyzer. The complex impedance spectrum (Z' vs Z') from the R-C circuit is a perfect semicircle, whereas the spectrum for the ferrite sample is a semicircular curve with its centre being depressed to below the real impedance axis. The depression of the semicircle for the ferrite is discussed as due to a deviation from the ideal Debye relaxation process. An equivalent circuit model that comprises of a capacitor and a resistor in parallel is suggested for the ferrite, but the result for the impedance is modified by including a factor that accounts for the distribution of the relaxation time. The simulated data from the circuit are in agreement with those from the experiment. The dispersion of the impedance is attributed to the conduction and polarization processes in the material

Identification of events with a secondary vertex in the experiment EXCHARM

International Nuclear Information System (INIS)

Bonyushkina, A.Yu.; Ivanov, V.V.; Potrebenikov, Yu.K.; Progulova, T.B.; Tatishvili, G.T.

1996-01-01

A simple algorithm for identifying events with secondary vertices (signal events) is suggested. The differences R x , R y between the largest and the smallest impact parameters D i of the tracks belonging to each of the events analyzed are used in establishing the identification criteria for signal and background events. An effective method for identifying the tracks associated with a particular secondary vertex in an event is developed. The method is based on the differences between the asymmetries exhibited by the sets D i for individual signal events and background events. The algorithm has been tested using simulated data. 12 refs., 7 figs

Effect of secondary compounds in forages on rumen micro-organisms quantified by 16S and 18S rRNA

International Nuclear Information System (INIS)

Wina, E.; Muetzel, S.; Hoffman, E.; Becker, K.; Makkar, H.P.S.

2005-01-01

A gas syringe method was used to evaluate the effect of secondary compounds from plant materials on in vitro fermentation products and microbial biomass. The experiment used Pennisetum purpureum, Morinda citrifolia fruit, Nothopanax scutellarium leaves, Sesbania sesban LS (low saponins type), Sesbania sesban HS (high saponins type) and Sapindus rarak fruit as substrates. The incubation was conducted with and without polyethylene glycol 6000 (PEG) addition for 24 hours. Gas production and short-chain fatty acids (SCFA) were analysed. Prokaryotic and eukaryotic concentrations were measured by quantifying 16S and 18S rRNA. The percentage increase in gas production due to PEG was very small (<5%) for all plant materials, which indicated that the biological effect of tannin in these plant materials is limited. TLC analysis revealed that all materials contained saponin, but only S. rarak, followed by S. sesban, contained a high diversity of saponins. S. sesban gave the highest (234 ml/g) while S. rarak gave the lowest gas production (115 ml/g). S. rarak gave the lowest SCFA production (3.57 mmole/g) and also the lowest ratio of acetate to propionate (1.76), indicating a change in pattern of SCFA production. Total elimination of eukaryotic concentration was evident from the absence of the 18S rRNA band when S. rarak and S. sesban were used as sole substrates. S. rarak also reduced the prokaryotic concentration. To use S. rarak as a defaunating agent without affecting prokaryotes, a crude saponin extract was prepared from S. rarak for further experiment. Different concentrations of crude saponins in a methanol extract of S. rarak fruit dissolved in rumen buffer were added to a substrate consisting of elephant grass and wheat bran (7:3 w/w). Microbial biomass yield was quantified by gravimetry and using rRNA as a marker. Addition of crude saponin extract from S. rarak to a high-roughage diet increased microbial biomass (MB) yield to 1.07 and 1.14 times MB yield of the

Molecular systematics of Barbatosphaeria (Sordariomycetes): multigene phylogeny and secondary ITS structure

Czech Academy of Sciences Publication Activity Database

Réblová, Martina; Réblová, K.; Štěpánek, Václav

2015-01-01

Roč. 35, December 2015 (2015), s. 21-38 ISSN 0031-5850 R&D Projects: GA ČR GAP506/12/0038 Institutional support: RVO:67985939 ; RVO:61388971 Keywords : Barbatosphaeria * molecular systematic * ITS secondary structures Subject RIV: EF - Botanics; EE - Microbiology, Virology (MBU-M) Impact factor: 5.725, year: 2015

THE PAST, THE PRESENT AND THE FUTURE OF THE COMPREHENSIVE SECONDARY SCHOOL COMPLEX NO 2 IN BIAŁY BÓR IN THE COMMON EDUCATIONAL SPACE

Directory of Open Access Journals (Sweden)

Izabela Stelmasiak

2017-04-01

Full Text Available The phenomenon of globalization, cultural changes, increased migration processes lead Europe/ the World to a model of a global village. The feeling of national identity, the awareness of common and different features resulting from the history, origin and culture play an important role for its inhabitants. The reality of a multicultural society is a subject of research and postulates of intercultural pedagogy.The above issue refers also to Poland  which has been a multicultural country for century. Nowadays the following minority groups should be distinguished: Germans, Belarusians, Ukrainians, Russians, Czechs, Slovaks, Jews and Armenians. The ethnic minorities include: Romani people, Lemkos and Tatars, however Silesians and Kashubians are proposed minorities.The system changes of Poland after the year 1990 caused a change of legislation and ratifying international conventions which determined the legal frames and the scope of the activity of minority groups.Ukrainians have a special position in the Pomeranian region due to a migration action “Vistula” which was carried out in the year 1947 by communist authorities. At present 6.5 thousand people live in the north of the country, most of them in  districts of Człuchów (1.19 % and Szczecinek (1.12 % of the total number of inhabitants.Education, especially communicative competences in a language of ancestors are a leading purpose of teaching. Complexes of Secondary Schools in Biały Bór, Górów Iławiecki, Legnica, Przemyśl, Bartoszyce and Ukrainian classes in Banie Mazurskie and Bielsko Podlaskie realize bilingual teaching. Apart from didactical and educational activity these schools play a role of the centres of pension trustees of Ukrainian culture, the culture which they promote in social environment.The Taras Szewczenko Complex of Secondary Schools No2 in Biały Bór is a representative school in Pomerania. The fate of the school present symbolically the fate of

Dark-red-emitting CdTe0.5Se0.5/Cd0.5Zn0.5S quantum dots: Effect of chemicals on properties

International Nuclear Information System (INIS)

Yang, Ping; Zhang, Aiyu; Li, Xiaoyu; Liu, Ning; Zhang, Yulan; Zhang, Ruili

2013-01-01

CdTe 0.5 Se 0.5 /Cd 0.5 Zn 0.5 S core/shell quantum dots (QDs) with a tunable photoluminescence (PL) range from yellow to dark red (up to a PL peak wavelength of 683 nm) were fabricated using various reaction systems. The core/shell QDs created in the reaction solution of trioctylamine (TOA) and oleic acid (OA) at 300 °C exhibited narrow PL spectra and a related low PL efficiency (38%). In contrast, the core/shell QDs prepared in the solution of 1-octadecene (ODE) and hexadecylamine (HDA) at 200 °C revealed a high PL efficiency (70%) and broad PL spectra. This phenomenon is ascribed that the precursor of Cd, reaction temperature, solvents, and ligands affected the formation process of the shell. The slow growth rate of the shell in the solution of ODE and HDA made QDs with a high PL efficiency. Metal acetate salts without reaction with HDA led to the core/shell QDs with a broad size distribution. - Graphical abstract: CdTe 0.5 Se 0.5 /Cd 0.5 Zn 0.5 S quantum dots (QDs) with tunable photoluminescence, high PL efficiency, and high stability through organic synthesis, in which chemicals affected the properties of the QDs. Display Omitted - Highlights: • CdTe 0.5 Se 0.5 /Cd 0.5 Zn 0.5 S quantum dots created via organic synthesis. • Chemicals affected the properties of the quantum dots. • The quantum dots revealed high photoluminescence efficiency and stability. • The quantum dots with tunable photoluminescence in a range from yellow to dark red. • The QDs are utilizable for various applications such as biological labeling

A Secondary Antibody-Detecting Molecular Weight Marker with Mouse and Rabbit IgG Fc Linear Epitopes for Western Blot Analysis.

Science.gov (United States)

Lin, Wen-Wei; Chen, I-Ju; Cheng, Ta-Chun; Tung, Yi-Ching; Chu, Pei-Yu; Chuang, Chih-Hung; Hsieh, Yuan-Chin; Huang, Chien-Chiao; Wang, Yeng-Tseng; Kao, Chien-Han; Roffler, Steve R; Cheng, Tian-Lu

2016-01-01

Molecular weight markers that can tolerate denaturing conditions and be auto-detected by secondary antibodies offer great efficacy and convenience for Western Blotting. Here, we describe M&R LE protein markers which contain linear epitopes derived from the heavy chain constant regions of mouse and rabbit immunoglobulin G (IgG Fc LE). These markers can be directly recognized and stained by a wide range of anti-mouse and anti-rabbit secondary antibodies. We selected three mouse (M1, M2 and M3) linear IgG1 and three rabbit (R1, R2 and R3) linear IgG heavy chain epitope candidates based on their respective crystal structures. Western blot analysis indicated that M2 and R2 linear epitopes are effectively recognized by anti-mouse and anti-rabbit secondary antibodies, respectively. We fused the M2 and R2 epitopes (M&R LE) and incorporated the polypeptide in a range of 15-120 kDa auto-detecting markers (M&R LE protein marker). The M&R LE protein marker can be auto-detected by anti-mouse and anti-rabbit IgG secondary antibodies in standard immunoblots. Linear regression analysis of the M&R LE protein marker plotted as gel mobility versus the log of the marker molecular weights revealed good linearity with a correlation coefficient R2 value of 0.9965, indicating that the M&R LE protein marker displays high accuracy for determining protein molecular weights. This accurate, regular and auto-detected M&R LE protein marker may provide a simple, efficient and economical tool for protein analysis.

2018-03-05T17:24:19Z https://www.ajol.info/index.php/index/oai oai ...

African Journals Online (AJOL)

article/55691 2018-03-05T17:24:19Z ajrh:ART Vulnerability of Nigerian Secondary School to Human Sex Trafficking in Nigeria Omorodion, FI Adolescents; Delta State; Edo State; in-school students; Nigeria; sex trafficking Sex trafficking ...

Quality control of the NPL-CRC secondary standard system used for activimeters calibration at IPEN, Sao Paulo, Brazil

International Nuclear Information System (INIS)

Martins, Elaine W.; Potiens, Maria da P.A.

2009-01-01

The objective of this study was to establish a quality control program to be applied at the NPL-CRC activimeter secondary standard system, used as reference to comparison in tests made with the work tertiary standard activimeter, Capintec basic CRC R -15BT, both belonging to the Calibration Laboratory of IPEN. The repeatability, reproducibility and the precision tests were performed using a sealed check source of 133 Ba, from Amersham. It was made 70 series of 10 measurements to each activimeter, totaling 1400 measurements. Considering the variation limit of 5% to precision and reproducibility tests in the nuclear medicine services, recommended by the Brazilian standard CNEN-NN-3.05, the results observed in the behavior of the IPEN activimeter were satisfactory. (author)

File list: InP.Bld.05.AllAg.Follicular_helper_T_cells [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available InP.Bld.05.AllAg.Follicular_helper_T_cells mm9 Input control Blood Follicular helpe...r T cells SRX1158862,SRX1143928,SRX1143929,SRX1143927 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/InP.Bld.05.AllAg.Follicular_helper_T_cells.bed ...

Two-Dimensional Raman Correlation Spectroscopy Study of Poly[(R)-3-hydroxybutyrate- co-(R)-3-hydroxyhexanoate] Copolymers.

Science.gov (United States)

Noda, Isao; Roy, Anjan; Carriere, James; Sobieski, Brian J; Chase, D Bruce; Rabolt, John F

2017-07-01

Two-dimensional correlation analysis was applied to the time-dependent evolution of Raman spectra during the isothermal crystallization of bioplastic, poly[(R)-3-hydroxybutyrate- co-(R)-3-hydroxyhexanoate] or PHBHx copolymer. Simultaneous Raman measurement of both carbonyl stretching and low-frequency crystalline lattice mode regions made it possible to carry out the highly informative hetero-mode correlation analysis. The crystallization process of PHBHx involves: (1) the early nucleation stage; (2) the primary growth of well-ordered crystals of PHBHx; and (3) the secondary crystal growth phase. The latter stage probably occurs in the inter-lamellar region, with an accompanying reduction of the amorphous component, which occurs most dominantly during the primary crystal growth. The development of a fully formed lamellar structure comprising the 2 1 helices occurs after the primary growth of crystals. In the later stage, secondary inter lamellar space crystallization occurs after the full formation of packed helices comprising the lamellae.

Characterizing Cross-Professional Collaboration in Research and Development Projects in Secondary Education

Science.gov (United States)

Schenke, Wouter; van Driel, Jan H.; Geijsel, Femke P.; Sligte, Henk W.; Volman, Monique L. L.

2016-01-01

Collaboration between practitioners and researchers can increasingly be observed in research and development (R&D) projects in secondary schools. This article presents an analysis of cross-professional collaboration between teachers, school leaders and educational researchers and/or advisers as part of R&D projects in terms of three…

Function of plant defense secondary metabolite in cytokinin degradation

Czech Academy of Sciences Publication Activity Database

Frébortová, Jitka

2010-01-01

Roč. 5, č. 5 (2010), s. 523-525 ISSN 1559-2316 R&D Projects: GA ČR GA522/05/0448; GA ČR GA301/08/1649 Institutional research plan: CEZ:AV0Z50380511 Keywords : cytokinin dehydrogenace * 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one * phenoxyl radiál Subject RIV: EF - Botanics http://www.landesbioscience.com/journals/psb/article/10965/

Do male secondary sexual characters signal ejaculate quality? A meta-analysis.

Science.gov (United States)

Mautz, Brian S; Møller, Anders P; Jennions, Michael D

2013-08-01

There are two reasons why researchers are interested in the phenotypic relationship between the expression of male secondary sexual characters (SSCs) and 'ejaculate quality' (defined as sperm/ejaculate traits that are widely assumed to increase female fertility and/or sperm competitiveness). First, if the relationship is positive then females could gain a direct benefit by choosing more attractive males for fertility assurance reasons ('the phenotype-linked fertility' hypothesis). Second, there is much interest in the direction of the correlation between traits favoured by pre-copulatory sexual selection (i.e. affecting mating success) and those favoured by post-copulatory sexual selection (i.e. increasing sperm competitiveness). If the relationship is negative this could lead to the two forms of selection counteracting each other. Theory predicts that the direction of the relationship could be either positive or negative depending on the underlying genetic variance and covariance in each trait, the extent of variation among males in condition (resources available to allocate to reproductive traits), and variation among males in the cost or rate of mating. We conducted a meta-analysis to determine the average relationship between the expression of behavioural and morphological male secondary sexual characters and four assays of ejaculate quality (sperm number, viability, swimming speed and size). Regardless of how the data were partitioned the mean relationship was consistently positive, but always statistically non-significant. The only exception was that secondary sexual character expression was weakly but significantly positively correlated with sperm viability (r = 0.07, P < 0.05). There was no significant difference in the strength or direction of the relationship between behavioural and morphological SSCs, nor among relationships using the four ejaculate quality assays. The implications of our findings are discussed. © 2013 The Authors. Biological Reviews �

Controlled ovarian stimulation with r-FSH plus r-LH vs. HMG plus r-FSH in patients candidate for IVF/ICSI cycles: An RCT

Directory of Open Access Journals (Sweden)

Ensieh Shahrokh Tehraninejad

2017-08-01

Full Text Available Background: Different combination of gonadotropin preparation has been introduced with no definite superiority of one over others in in vitro fertilization (IVF, but individualized regimens for each patient are needed. Objective: The aim of the present study was to investigate the effect of controlled ovarian stimulation with recombinant- follicle stimulating hormone (r-FSH plus recombinant-luteinizing hormone (rLH versus human menopausal gonadotropin (HMG plus r-FSH on fertility outcomes in IVF patients. Materials and Methods: This is a randomized clinical trial study that was performed from October 2014-April 2016 on 140 infertile patients with a set of inclusion criteria that referred to infertility clinics in Vali- asr and Gandhi Hospital in Tehran. The women were randomly divided into two treatment groups. The first group (n=70 received rFSH from the second day of cycle and was added HMG in 6th day and the 2nd group (n=70, received rFSH from the second day of cycle and was added recombinant-LH in 6th day. Then ovum Pick-Up and embryo transfer were performed. In this study, we assessed the outcomes such as; chemical and clinical pregnancy rate, live birth and abortion rate. Results: Number of follicles in ovaries, total number of oocytes or M2 oocytes and quality of fetuses has no significant differences between two groups (p>0.05. Total number of fetuses were significantly higher in patients who received rFSH + HMG (p=0.02. Fertility outcomes consisted of: live birth rate, chemical pregnancy and clinical pregnancy rate were higher in rFSH + HMG group in comparison to rFSH +r-LH group (p<0.05. Conclusion: It seems that in IVF patients, HMG + rFSH used for controlled ovarian hyperstimulation have better effects on fertility outcomes, but in order to verify the results, it is recommended to implement studies on more patients.

Clinical significance of combined measurement of serum sex hormones in secondary amenorrhea

International Nuclear Information System (INIS)

Chen Boxun; Chen Yue; Gan Xilun

2004-01-01

Objective: To study the clinical significance of changes of levels of serum sex hormones in the diagnosis of the types of secondary amenorrhea. Methods: Serum sex hormones levels were measured with chemiluminescence in 100 patients with secondary amenorrhea and 42 controls. The serum hormones determined were: estradiol (E 2 )-, progesterone (PROG), follicle stimulating hormone (FSH)-, luteinizing hormone (LH), prolactin (PRL), testosterone (TSTO). Results: Patients with secondary amenorrhea had significantly higher levels of serum FSH, LH and PRL ( P 2 (P<0.05) than those in the controls. Serum levels of PROG and TSTO were about the same in the patients and controls. Conclusion: Determination of serum hormones levels with chemiluminescence is clinically useful for diagnosis of the types of secondary amenorrhea. (authors)

2018-05-07T02:19:42Z https://www.ajol.info/index.php/all/oai oai:ojs ...

African Journals Online (AJOL)

article/67064 2018-05-07T02:19:42Z jstcr:ART Traumatic Fracture of Thin Pedicles Secondary to Extradural Meningeal Cyst Yanni, DS Mammis, A Thaker, NG Goldstein, IM Arachnoid cyst, Cerebrospinal fluid diverticula, extradural meningeal cyst, ...

DasR is a pleiotropic regulator required for antibiotic production, pigment biosynthesis, and morphological development in Saccharopolyspora erythraea.

Science.gov (United States)

Liao, Cheng-Heng; Xu, Ya; Rigali, Sébastien; Ye, Bang-Ce

2015-12-01

The GntR-family transcription regulator, DasR, was previously identified as pleiotropic, controlling the primary amino sugar N-acetylglucosamine (GlcNAc) and chitin metabolism in Saccharopolyspora erythraea and Streptomyces coelicolor. Due to the remarkable regulatory impact of DasR on antibiotic production and development in the model strain of S. coelicolor, we here identified and characterized the role of DasR to secondary metabolite production and morphological development in industrial erythromycin-producing S. erythraea. The physiological studies have shown that a constructed deletion of dasR in S. erythraea resulted in antibiotic, pigment, and aerial hyphae production deficit in a nutrient-rich condition. DNA microarray assay, combined with quantitative real-time reverse transcription PCR (qRT-PCR), confirmed these results by showing the downregulation of the genes relating to secondary metabolite production in the dasR null mutant. Notably, electrophoretic mobility shift assays (EMSA) showed DasR as being the first identified regulator that directly regulates the pigment biosynthesis rpp gene cluster. In addition, further studies indicated that GlcNAc, the major nutrient signal of DasR-responsed regulation, blocked secondary metabolite production and morphological development. The effects of GlcNAc were shown to be caused by DasR mediation. These findings demonstrated that DasR is an important pleiotropic regulator for both secondary metabolism and morphological development in S. erythraea, providing new insights for the genetic engineering of S. erythraea with increased erythromycin production.

Structural Evolution of the R-T Phase Boundary in KNN-Based Ceramics

KAUST Repository

Lv, Xiang

2017-10-04

Although a rhombohedral-tetragonal (R-T) phase boundary is known to substantially enhance the piezoelectric properties of potassium-sodium niobate ceramics, the structural evolution of the R-T phase boundary itself is still unclear. In this work, the structural evolution of R-T phase boundary from -150 °C to 200 °C is investigated in (0.99-x)K0.5Na0.5Nb1-ySbyO3-0.01CaSnO3-xBi0.5K0.5HfO3 (where x=0~0.05 with y=0.035, and y=0~0.07 with x=0.03) ceramics. Through temperature-dependent powder X-ray diffraction (XRD) patterns and Raman spectra, the structural evolution was determined to be Rhombohedral (R, <-125 °C) → Rhombohedral+Orthorhombic (R+O, -125 °C to 0 °C) → Rhombohedral+Tetragonal (R+T, 0 °C to 150 °C) → dominating Tetragonal (T, 200 °C to Curie temperature (TC)) → Cubic (C, >TC). In addition, the enhanced electrical properties (e.g., a direct piezoelectric coefficient (d33) of ~450±5 pC/N, a conversion piezoelectric coefficient (d33*) of ~580±5 pm/V, an electromechanical coupling factor (kp) of ~0.50±0.02, and TC~250 °C), fatigue-free behavior, and good thermal stability were exhibited by the ceramics possessing the R-T phase boundary. This work improves understanding of the physical mechanism behind the R-T phase boundary in KNN-based ceramics and is an important step towards their adoption in practical applications. This article is protected by copyright. All rights reserved.

D E Gberevbie, AO Shodipo and FO Oviasogie Leadership and ...

African Journals Online (AJOL)

Oduor

Department of Political Science and International Relations. Covenant ... leadership and proper accountability in the management of public resources. ..... years of the project and investment of colossal sums of public funds, its objective is ... to enable a company, Sagem S.A. of France, to execute the contract (cited in Onah.

A gene-wide investigation on polymorphisms in the taste receptor 2R14 (TAS2R14) and susceptibility to colorectal cancer

Czech Academy of Sciences Publication Activity Database

Campa, D.; Vodička, Pavel; Pardini, Barbara; Naccarati, Alessio; Carrai, M.; Vodičková, Ludmila; Novotný, J.; Hemminki, K.; Försti, A.; Barale, R.; Canzian, F.

2010-01-01

Roč. 11, č. 1 (2010), s. 88-93 ISSN 1471-2350 R&D Projects: GA ČR GA310/05/2626 Institutional research plan: CEZ:AV0Z50390512 Keywords : colorectal cancer * TAS2R14 Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 2.439, year: 2010

Correlation between classification and secondary screw penetration in proximal humeral fractures.

Directory of Open Access Journals (Sweden)

Qiuke Wang

Full Text Available In this study, we investigated the correlation between fracture classification and secondary screw penetration.We retrospectively identified 189 patients with displaced proximal humeral fractures treated by ORIF at our hospital between June 2006 and June 2013. All fractures were classified radiographically before surgery and follow-up for least 2 years after surgery was recommended. At each follow-up, radiographs were taken in three orthogonal views to evaluate secondary screw penetration.The study population consisted of 189 patients. Of these, 70 were male and 119 female, with a mean age of 59.1 years; the mean follow-up time was 28.5 months. Secondary screw penetration occurred in 26 patients. The risk of developing secondary screw penetration was 11.3-fold higher in four-part fractures than two-part fractures (P 0.05.Patients with four-part fractures, type C fractures and medial hinges disruption are vulnerable to secondary screw penetration. This allows additional precautions to be instituted and measures to be taken as needed.

2018-05-05T05:37:19Z https://www.ajol.info/index.php/index/oai oai ...

African Journals Online (AJOL)

article/57150 2018-05-05T05:37:19Z mlr:ART Revisiting Company Law with the ... in Mizan Law Review, the review's name, the author's name, the volume number, and the page numbers of the article shall be stated.c) Users of hard and soft ...

Effect of cerium addition on the microstructure, electrical and relaxor behavior of Sr{sub 0.5}Ba{sub 0.5}Nb{sub 2}O{sub 6} ceramics

Energy Technology Data Exchange (ETDEWEB)

Velayutham, T.S., E-mail: t_selvi@um.edu.my; Salim, N.I.F.; Gan, W.C.; Abd Majid, W.H.

2016-05-05

Sr{sub 0.5}Ba{sub 0.5}Nb{sub 2}O{sub 6} (SBN50) ceramic doped with different concentrations of Cerium (Ce) according to the stoichiometry formulation of Sr{sub 0.5-3y/2}Ba{sub 0.5}Ce{sub y}Nb{sub 2}O{sub 6} (Ce-SBN) with y = 0, 0.01, 0.02, 0.03, 0.04 and 0.05 was prepared using the conventional solid state reaction method. The morphology, structure, and electrical properties of the samples were studied using field emission scanning electron microscope (FESEM), X-ray diffraction (XRD), ferroelectric and dielectric spectroscopy, respectively. The FESEM images reveal a strong influence of cerium on the SBN microstructure. The X-ray diffraction patterns show that all compositions of SBN ceramic exhibit tetragonal tungsten bronze structure. As the dopant concentration, y increased, both unit cell volume and axial ratio c/a decreased gradually. In addition, dopant incorporation lowers the phase transition temperature, T{sub m}. As a result, all practical parameters are sufficiently increased, i.e. the dielectric constant and remnant polarization. SBN50 doped with a 3% Ce sample is most attractive for practical applications due to its high remnant polarization, P{sub r} = 58.6 μC/cm{sup 2} and dielectric constant, ε’ ≈ 8000 (10 kHz) at room temperature, respectively. - Highlights: • Sr{sub 0.5-3y/2}Ba{sub 0.5}Ce{sub y}Nb{sub 2}O{sub 6} synthesized using solid-state reaction method. • Cerium dopant improved the overall properties of SBN. • Dopant incorporation lowers the phase transition temperature, T{sub m}. • 3% Ce dopant exhibits best functional properties among the rest of the composition. • The P{sub r} of 3%Ce-doped SBN is 58.6 μC/cm{sup 2} and ε’ ≈ 8000 (10 kHz) at room temperature.

Secondary patents in the pharmaceutical industry: missing the wood for the trees?

Science.gov (United States)

Kiran, Saritha; Kulkarni, Mohan

2018-03-01

The critics of the Innovator pharmaceutical industry allege that secondary patents are trivial modifications over the primary patent, which extend its term and delay the entry of the generics in the market place. The protagonists regard secondary patents a result of continuous research and development (R&D), which help them introduce and protect new, differentiated products. Areas covered: The areas covered are Product life cycle management (PLCM), Drug approval process, Orange book (OB) listed patents, US patent data. Expert opinion: Our analysis of the patents and products of four innovators viz., AstraZeneca, Takeda, Eisai and Wyeth in the field of proton pump inhibitors (PPI's) and Merck and Pfizer in the field of Statins shows that secondary patents help innovators sustain competition against other innovators in the specific product segment. The number of secondary patents listed in OB per NCE depends on the innovators interest in exploiting the NCE, the success of R & D effort and product lifecycle management strategy in the wake of market competition. Market entry decisions of innovators are strategic rather than a mere fallout of the secondary patents granted. Entry of another innovator is more unpredictable and hurts the first entrant more vis a vis the entry of generics who can enter the market when the patents protecting a product are no more enforceable, and hence more predictable. Generic entry in the field of PPI's shows that the term of the primary patent is not extended by the secondary patents.

Crystallization of Sr0.5Ba0.5Nb2O6 Thin Films on LaNiO3 Electrodes by RF Magnetron Reactive Sputtering

Science.gov (United States)

Jong, Chao-An; Gan, Jon-Yiew

2000-02-01

Strontium barium niobium (Sr0.5Ba0.5Nb2O6) (SBN) thin films are prepared on conductive-oxide LNO (LaNiO3) electrodes by the rf magnetron sputtering system. Instead of conventional furnace annealing, SBN thin films are crystallized by rapid thermal annealing (RTA) above 700°C for 5 min. The textured SBN films are crystallized with two orientations: one is the (001) or (310) direction, and the other is the (002) or (620) direction. Films compositions measured by the electron spectroscopy of chemical analysis (ESCA) quantitative analysis method show nearly the same stoichiometric ratio as the target. The depth profiles of SBN films and the target are examined by secondary ion mass spectrometer (SIMS). The concentrations of the films are quite uniform. After being heat treated at 800°C for 5 min by RTA, La and Ni diffuse into the SBN film. The diffusion coefficient of La in SBN films is also calculated.

Investigation on structural, Mössbauer and ferroelectric properties of (1−x)PbFe{sub 0.5}Nb{sub 0.5}O{sub 3}–(x)BiFeO{sub 3} solid solution

Energy Technology Data Exchange (ETDEWEB)

Dadami, Sunanda T.; Matteppanavar, Shidaling; Shivaraja, I. [Department of Physics, JB Campus, Bangalore University, Bangalore 560056 (India); Rayaprol, Sudhindra [UGC-DAE-Consortium for Scientific Research, Mumbai Centre, BARC Campus, Mumbai 400085 (India); Angadi, Basavaraj, E-mail: brangadi@gmail.com [Department of Physics, JB Campus, Bangalore University, Bangalore 560056 (India); Sahoo, Balaram [Materials Research Centre, Indian Institute of Science, Bangalore 560012 (India)

2016-11-15

In this study, (1−x)PbFe{sub 0.5}Nb{sub 0.5}O{sub 3}(PFN)–(x)BiFeO{sub 3}(BFO) multiferroic solid solutions with x=0.0, 0.1, 0.2, 0.3 and 0.4 were synthesized through single step solid state reaction method and characterized thoroughly through X-ray Diffraction (XRD), Scanning Electron Microscopy (SEM), Fourier Transform Infra-Red (FTIR), Raman, Mössbauer spectroscopy and ferroelectric studies. The room temperature (RT) XRD studies confirmed the formation of single phase with negligible amount of secondary phases (x=0.2 and 0.4). The zoomed XRD patterns of (1−x)PFN–(x)BFO solid solutions showed the clear structural phase transition from monoclinic (Cm) to rhombohedral (R3c) at x=0.4. The Raman spectra of the (1−x)PFN–(x)BFO solid solutions showed the composition dependent phase transition from monoclinic (Cm) to rhombohedral (R3c). With increasing x in PFN, the modes related monoclinic symmetry changes to those of rhombohedral symmetry. The RT Mössbauer spectroscopy results evidenced the existence of composition dependent phase transition from paramagnetic to weak antiferromagnetic ordering and weak antiferromagnetic to antiferromagnetic ordering. The Mössbauer spectroscopy showed paramagnetic behavior with a doublet for x=0.0, 0.1 and 0.2 are shows the weak antiferromagnetic with paramagnetic ordering. For x=0.3 and 0.4 shows the sextet pattern and it is a clear evidence of antiferromagnetism. The ferroelectric (P–E) loops at RT indicate the presence of small polarization, as the x concentration increases in PFN, the remnant polarization and coercive field were decreased, which may due to the increase in the conductivity and leaky behavior of the samples. - Highlights: • Structural, Mössbauer, ferroelectric studies on (1−x)PFN–xBiFeO{sub 3} multiferroics. • Composition dependent changes in crystallographic and magnetic structure. • System exhibits phase transition from monoclinic to rhombohedral with x. • Supporting results from Raman

Study of the Vapor-Liquid Coexistence Curve and the Critical Curve for Nonazeotropic Refrigerant Mixture R152a + R114 System

Science.gov (United States)

Kabata, Yasuo; Higashi, Yukihiro; Uematsu, Masahiko; Watanabe, Koichi

Measurements of the vapor-liquid coexistence curve in the critical region for the refrigerant mixture of R152a (CH3CHF2: 1, l-difluoroethane) +R 114 (CCIF2CCIF2 :1, 2-dichloro-1, 1, 2, 2-tetrafluoroethane) system were made by visual observation of the disappearance of the meniscus at the vapor-liquid interface within an optical cell. Forty-eight saturated densities along the vapor-liquid coexistence curve between 204 and 861 kg·m-3 for five different compositions of 10, 20, 50, 80 and 90 wt% R 152a were obtained in the temperature range 370 to 409 K. The experimental errors of temperature, density, and mass fraction were estimated within ±10mK, ±0.5% and +0.05 %, respectively. On the basis of these measurements, the critical parameters of five different compositions for the R 152a +R 114 system were determined in consideration of the meniscus disappearance level as well as intensity of the critical opalescence. In accordance with the previous results of three other refrigerant mixtures, i.e., R 12 +R 22 system, R 22 +R 114 system and R 13B1 + R 114 system, the coexistence curve and critical curve on the temperature-density diagram for binary refrigerant mixtures were discussed. In addition, correlations of its composition dependence for this system were proposed.

Oligonucleic Acid Drug List: monrd0025 [Oligonucleic Acid Drug Database[Archive

Lifescience Database Archive (English)

Full Text Available com/kynamro-drug.htm, http://www.kegg.jp/dbget-bin/www_bget?D08946, https://www.clinicaltrialsregister.eu/ct...r-search/trial/2004-003934-32/DE, https://www.clinicaltrialsregister.eu/ctr-searc...h/trial/2005-003449-15/GB, http://www.ncbi.nlm.nih.gov/pubmed/21210756 https://www.clinicaltrialsregister.eu.../ctr-search/trial/2005-003450-10/GB, https://www.clinicaltrialsregister.eu/ctr-search/trial/2007-005140-24/N...L, https://www.clinicaltrialsregister.eu/ctr-search/trial/2011-001480-42/ES, https://www.clinicaltrialsreg

The Area of Secondary Hyperalgesia following Heat Stimulation in Healthy Male Volunteers

DEFF Research Database (Denmark)

Hansen, Morten Sejer; Wetterslev, Jørn; Pipper, Christian Bressen

2016-01-01

, with a minimum interval of 7 days. Additionally, heat pain detection threshold and pain during thermal stimulation (45°C for 1 min.), and the psychological tests Pain Catastrophizing Scale and Hospital Anxiety and Depression Score were applied. RESULTS: For areas of secondary hyperalgesia, an intra...... and above the 3rd quartile considering all included participants. Heat pain detection threshold predicted area of secondary hyperalgesia with an adjusted R2 of 0.20 (P = 0.0006). CONCLUSIONS: We have demonstrated a low intra-individual, and a high inter-individual variation in thermally induced secondary...

THE PECULIAR PHOTOMETRIC PROPERTIES OF 2010 WG9: A SLOWLY ROTATING TRANS-NEPTUNIAN OBJECT FROM THE OORT CLOUD

Energy Technology Data Exchange (ETDEWEB)

Rabinowitz, David; Schwamb, Megan E.; Hadjiyska, Elena [Center for Astronomy and Astrophysics, Yale University, New Haven, CT (United States); Tourtellotte, Suzanne [Astronomy Department, Yale University, New Haven, CT (United States); Rojo, Patricio [Department of Astronomy, University of Chile, Santiago (Chile)

2013-07-01

We present long-term BVRI observations of 2010 WG9, an {approx}100 km diameter trans-Neptunian object (TNO) with an extremely high inclination of 70 Degree-Sign discovered by the La Silla-QUEST southern sky survey. Most of the observations were obtained with ANDICAM on the SMARTS 1.3 m at Cerro Tololo, Chile from 2010 December to 2012 November. Additional observations were made with EFOSC2 on the 3.5 m NTT telescope of the European Southern Observatory at La Silla, Chile in 2011 February. The observations reveal a sinusoidal light curve with amplitude 0.14 mag and period 5.4955 {+-} 0.0025 days, which is likely half the true rotation period. Such long rotation periods have previously been observed only for tidally evolved binary TNOs, suggesting that 2010 WG9 may be such a system. We predict a nominal separation of at least 790 km, resolvable with the Hubble Space Telescope and ground-based systems. We measure B - R = 1.318 {+-} 0.029 and V - R = 0.520 {+-} 0.018, consistent with the colors of modestly red Centaurs and Damocloids. At I-band wavelengths, we observe an unusually large variation of color with rotational phase, with R - I ranging from 0.394 {+-} 0.025 to 0.571 {+-} 0.044. We also measure an absolute R-band absolute magnitude of 7.93 {+-} 0.05 and solar phase coefficient of 0.049 {+-} 0.019 mag deg{sup -1}.

The clinical significance of serum Leptin in the pathogenesis of 2DM and obesity

International Nuclear Information System (INIS)

Liu Chunyu; Lu Kuan; Gao Yanyan

2001-01-01

Objective: To study the relationship between serum Leptin ad insulin, body fat distribution and testosterone in 2-DM patients. Methods: The fasting blood serum Leptin and insulin levels in 65 2DM patients and 42 controls were measured by radioimmunoassay. Abdominal subcutaneous adipose tissue volume (ASF) and abdominal visceral adipose tissue volume (AVF) were measured by spiral CT SSD soft-ware in 32 2DM patients. The authors also measured the Leptin before and 2h after a 75 g OGTT in 34 2DM patients and fasting plasma testosterone in 30 2DM males. Results: DM group and normal group had equal number of females and were matched in BMI. Baseline plasma Leptin concentrations were not significantly different between the groups (P 14 mmol/L) had lower Leptin levels (P < 0.05). Sex, BMI, ASF were important factors contributing to the serum Leptin. The Leptin concentrations were significantly positively correlated with BMI (r 0.57, P0.0001), ASF(r = 0.67 P0.025) and insulin (r = 0.47, P0.0013) and was negative correlated with the serum testosterone (r = -0.061, P0.025). Conclusion: There were no abnormal Leptin levels in 2DM implies, suggesting that Leptin might not be the main causing factor in 2DM. The poorly metabolic controlled patients might have lack of Leptin. The lower Leptin levels in men might be caused by testosterone, sex BMI, ASF were important factors contributing to the serum Leptin levels

Secondary Structural Models (16S rRNA of Polyhydroxyalkanoates Producing Bacillus Species Isolated from Different Rhizospheric Soil: Phylogenetics and Chemical Analysis

Directory of Open Access Journals (Sweden)

Swati Mohapatra

2016-09-01

Full Text Available Polyhydroxyalkanoates (PHAs producing bacterial isolates are gaining more importance over the world due to the synthesis of a biodegradable polymer which is extremely desirable to substitute synthetic plastics. PHAs are produced by various microorganisms under certain stress conditions. In this study, sixteen bacterial isolates characterized previously by partial 16S rRNA gene sequencing (NCBI Accession No. KF626466 to KF626481 were again stained by Nile red after three years of preservation in order to confirm their ability to accumulate PHAs. Also, phylogenetic analysis carried out in the present investigation evidenced that the bacterial species belonging to genus Bacillus are the dominant flora of the rhizospheric region, with a potentiality of biodegradable polymer (PHAs production. Again, RNA secondary structure prediction hypothesized that there is no direct correlation between RNA folding pattern stability with a rate of PHAs production among the selected isolates of genus Bacillus.

NCBI nr-aa BLAST: CBRC-RNOR-05-0081 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-RNOR-05-0081 ref|NP_036916.1| cannabinoid receptor 1 (brain) [Rattus norvegicu...s] sp|P20272|CNR1_RAT Cannabinoid receptor 1 (CB1) (CB-R) (Brain-type cannabinoid receptor) emb|CAA39332.1| CB1 cann...abinoid receptor [Rattus norvegicus] gb|AAA99067.1| neuronal cannabinoid receptor gb|EDL98589.1| cann...abinoid receptor 1 (brain) [Rattus norvegicus] prf||1613453A cannabinoid receptor NP_036916.1 0.0 100% ...

NCBI nr-aa BLAST: CBRC-TGUT-05-0032 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-TGUT-05-0032 ref|NP_036916.1| cannabinoid receptor 1 (brain) [Rattus norvegicu...s] sp|P20272|CNR1_RAT Cannabinoid receptor 1 (CB1) (CB-R) (Brain-type cannabinoid receptor) emb|CAA39332.1| CB1 cann...abinoid receptor [Rattus norvegicus] gb|AAA99067.1| neuronal cannabinoid receptor gb|EDL98589.1| cann...abinoid receptor 1 (brain) [Rattus norvegicus] prf||1613453A cannabinoid receptor NP_036916.1 0.0 92% ...

Laser post-ionization secondary neutral mass spectroscopy

International Nuclear Information System (INIS)

Gruen, D.M.; Pellin, M.J.; Calaway, W.F.; Young, C.E.

1987-01-01

Three different instruments using laser ionization techniques will be described. Results from the SARISA instrument with a demonstrated figure of merit of .05 (atoms detected/atoms sputtered) for resonance ionization; detection of Fe at the sub-part-per-billion level in ultrapure Si; and features of the instrument such as energy and angle refocusing time-of-flight (EARTOF) mass spectrometer and multiplexing for simultaneous detection of secondary ions and neutrals. 12 refs., 3 figs

Improved multiferroic properties in (1−x)BiFeO{sub 3}–xBaTi{sub 0.95}(Yb{sub 0.5}Nb{sub 0.5}){sub 0.05}O{sub 3} system (0≤x≤0.3)

Energy Technology Data Exchange (ETDEWEB)

Amouri, A., E-mail: amouri.amira00@gmail.com [Laboratoire des Matériaux Ferroélectriques (LMF), LR-Physique-Mathématiques et Applications, Université de Sfax, Faculté des Sciences de Sfax(FSS), Route de Soukra km3,5 B.P.1171, 3000 Sfax (Tunisia); Le laboratoire des Colloïdes, Verre, et Nanomatériaux, UMRCNRS 5587,Unité mixte de recherche 5587-CNRS-UM2-Université Montpellier 2, F-34095 Montpellier (France); Abdelmoula, N.; Khemakhem, H. [Laboratoire des Matériaux Ferroélectriques (LMF), LR-Physique-Mathématiques et Applications, Université de Sfax, Faculté des Sciences de Sfax(FSS), Route de Soukra km3,5 B.P.1171, 3000 Sfax (Tunisia)

2016-11-01

Polycrystalline samples of (1−x)BiFeO{sub 3}–xBaTi{sub 0.95}(Yb{sub 0.5}Nb{sub 0.5}){sub 0.05}O{sub 3} (x=0, 0.1, 0.2 and 0.3) were prepared by the conventional solid state reaction method. The phase purity and composition were cheeked using powder X-ray diffraction (XRD), energy dispersive X-ray spectroscopy (EDX) and X-ray photoelectron spectroscopy (XPS). The grain size and morphology of the ceramics were confirmed by scanning electron microscopy (SEM). X-ray diffraction showed that these compounds crystallized, at room temperature, in the Rhomboedral R3c for x=0 and in tetragonal P4mm for compositions 0.1≤x≤0.3 distorted perovskite structures. The BaTi{sub 0.95}(Yb{sub 0.5}Nb{sub 0.5}){sub 0.05}O{sub 3} substitution led to an improvement of magnetic and ferroelectric properties at room temperature. The highest magnetization was reported for composition x=0.2 which was due to the enhancement of canting angles and the suppression of cycloid spin structure, as confirmed by {sup 57}Fe Mössbauer spectroscopy and the presence of Fe{sup 2+}, as detected by XPS. The electric polarization increased significantly for doped samples, which proves the enhancement of the ferroelectric behavior and resistivity of our ceramics. Large electric field induced strains were observed for 0.7BiFeO{sub 3}-0.3BaTi{sub 0.95}(Yb{sub 0.5}Nb{sub 0.5}){sub 0.05}O{sub 3}, as an evidence of piezoelectric behavior. These results show that BaTi{sub 0.95}(Yb{sub 0.5}Nb{sub 0.5}){sub 0.05}O{sub 3} doped BiFeO{sub 3} is a promising multiferroic material. - Highlights: • (1−x)BiFeO{sub 3}–xBa[Ti{sub 0.95}(Yb{sub 0.5}Nb{sub 0.5}){sub 0.05}]O{sub 3} is a new multiferroic system. • Doped BiFeO{sub 3} ceramics crystallize in tetragonal distorted perovskite. • Magnetic properties at room temperature were improved.

Recognition determinants for proteins and antibiotics within 23S rRNA

DEFF Research Database (Denmark)

Douthwaite, Stephen Roger; Voldborg, Bjørn Gunnar Rude; Hansen, Lykke Haastrup

1995-01-01

Ribosomal RNAs fold into phylogenetically conserved secondary and tertiary structures that determine their function in protein synthesis. We have investigated Escherichia coli 23S rRNA to identify structural elements that interact with antibiotic and protein ligands. Using a combination of molecu......Ribosomal RNAs fold into phylogenetically conserved secondary and tertiary structures that determine their function in protein synthesis. We have investigated Escherichia coli 23S rRNA to identify structural elements that interact with antibiotic and protein ligands. Using a combination......-proteins L10.(L12)4 and L11 and is inhibited by interaction with the antibiotic thiostrepton. The peptidyltransferase center within domain V is inhibited by macrolide, lincosamide, and streptogramin B antibiotics, which interact with the rRNA around nucleotide A2058. Drug resistance is conferred by mutations...

2018-05-01T20:06:10Z https://www.ajol.info/index.php/all/oai oai:ojs ...

African Journals Online (AJOL)

article/79059 2018-05-01T20:06:10Z gjedr:ART The roles of games in teaching and learning of mathematics in junior secondary schools Orim, RE Ekwueme, CO The paper examined the role of games in teaching and learning of Mathematics in ...

Liquid phase interaction in TiC0,5N0,5-TiNi-Mo and TiC0,5N0,5-TiNi-Ti-Mo

International Nuclear Information System (INIS)

Askarova, L.Kh; Grigorov, I.G.; Zajnulin, Yu.G.

1998-01-01

Using the methods of X ray diffraction analysis, electron microscopy and X ray spectrum microanalysis a study was made into specific features of phase and structure formation in alloys TiC 0,5 N 0,5 -TiNi-Mo and TiC 0,5 N 0,5 -TiNi-Mo in the presence of a liquid phase at temperatures of 1380-1600 deg C. It is revealed that the physical and chemical processes taking place during the liquid-phase sintering result in the formation of a three-phase alloy consisting of nonstoichiometric titanium carbonitride TiC 0.5-x N 0.5-x , a molybdenum base solid solution of titanium, nickel and carbon Mo(Ti, Ni, C) and one of two intermetallic compounds, either TiNi or Ni 3 Ti. Metallic element concentration in individual phase constituents of the alloy is determined by means of X ray spectrum microanalysis

A Psychometric Evaluation of the Achievement Goal Questionnaire-Revised in Singapore Secondary Students

Science.gov (United States)

Ning, Hoi Kwan

2017-01-01

This study examined the psychometric properties of the Achievement Goal Questionnaire-Revised (AGQ-R) in a sample of Singapore secondary students (N = 1,171). Confirmatory factor analyses provided support for the AGQ-R in measuring the four achievements goals delineated in the 2 × 2 framework. Measurement invariance across ethnic groups was…

LEYENDO P4L4BR4S y NÚM3R05

Directory of Open Access Journals (Sweden)

Manuel Carreiras

2008-04-01

Full Text Available Un aspecto clave en lectura es el proceso de reconocimiento de las letras en las palabras. Dicho proceso tiene un componente de normalización de la información sensorial conforme a unos patrones almacenados. Un ejemplo es que cuando leemos un ítem como M4T3R14L se activa inicialmente el significado de MATERIAL.

Effect of project work on secondary school students science process ...

African Journals Online (AJOL)

The study investigated the effect of students' project work on secondary school science process skills acquisition in Biology. The study was carried out in Owerri North Local Government Area of Imo State. Three research questions guided the study and three null hypotheses were postulated and tested at 0.05 level of ...

Mutual Coupling Between Meteorological Parameters and Secondary Microseisms

Czech Academy of Sciences Publication Activity Database

Holub, Karel; Kalenda, Pavel; Rušajová, Jana

2013-01-01

Roč. 24, č. 6 (2013), s. 933-949 ISSN 1017-0839 R&D Projects: GA MŠk LM2010008 Institutional support: RVO:68145535 ; RVO:67985891 Keywords : secondary microseisms * meteorological elements * statistics Subject RIV: DC - Siesmology, Volcanology, Earth Structure Impact factor: 1.061, year: 2013 http://tao.cgu.org.tw/pdf/v246p933.pdf

Dark-red-emitting CdTe{sub 0.5}Se{sub 0.5}/Cd{sub 0.5}Zn{sub 0.5}S quantum dots: Effect of chemicals on properties

Energy Technology Data Exchange (ETDEWEB)

Yang, Ping, E-mail: mse_yangp@ujn.edu.cn; Zhang, Aiyu; Li, Xiaoyu; Liu, Ning; Zhang, Yulan; Zhang, Ruili

2013-08-15

CdTe{sub 0.5}Se{sub 0.5}/Cd{sub 0.5}Zn{sub 0.5}S core/shell quantum dots (QDs) with a tunable photoluminescence (PL) range from yellow to dark red (up to a PL peak wavelength of 683 nm) were fabricated using various reaction systems. The core/shell QDs created in the reaction solution of trioctylamine (TOA) and oleic acid (OA) at 300 °C exhibited narrow PL spectra and a related low PL efficiency (38%). In contrast, the core/shell QDs prepared in the solution of 1-octadecene (ODE) and hexadecylamine (HDA) at 200 °C revealed a high PL efficiency (70%) and broad PL spectra. This phenomenon is ascribed that the precursor of Cd, reaction temperature, solvents, and ligands affected the formation process of the shell. The slow growth rate of the shell in the solution of ODE and HDA made QDs with a high PL efficiency. Metal acetate salts without reaction with HDA led to the core/shell QDs with a broad size distribution. - Graphical abstract: CdTe{sub 0.5}Se{sub 0.5}/Cd{sub 0.5}Zn{sub 0.5}S quantum dots (QDs) with tunable photoluminescence, high PL efficiency, and high stability through organic synthesis, in which chemicals affected the properties of the QDs. Display Omitted - Highlights: • CdTe{sub 0.5}Se{sub 0.5}/Cd{sub 0.5}Zn{sub 0.5}S quantum dots created via organic synthesis. • Chemicals affected the properties of the quantum dots. • The quantum dots revealed high photoluminescence efficiency and stability. • The quantum dots with tunable photoluminescence in a range from yellow to dark red. • The QDs are utilizable for various applications such as biological labeling.

MiR-155 modulates the progression of neuropathic pain through targeting SGK3.

Science.gov (United States)

Liu, Shaoxing; Zhu, Bo; Sun, Yan; Xie, Xianfeng

2015-01-01

This study aimed to illustrate the potential effects of miR-155 in neuropathic pain and its potential mechanism. Spragure-Dawley (SD) rats were used for neuropathic pain model of bilateral chronic constriction injury (bCCI) construction. Effects of miR-155 expression on pain threshold of mechanical stimuli (MWT), paw withdrawal threshold latency (PMTL) and cold threshold were analyzed. Target for miR-155 was analyzed using bioinformatics methods. Moreover, effects of miR-155 target gene expression on pain thresholds were also assessed. Compared with the controls and sham group, miR-155 was overexpressed in neuropathic pain rats (P<0.05), but miR-155 slicing could significantly decreased the pain thresholds (P<0.05). Serum and glucocorticoid regulated protein kinase 3 (SGK3) was predicted as the target gene for miR-155, and miR-155 expression was negatively correlated to SGK3 expression. Furthermore, SGK3 overexpression could significantly decreased the pain thresholds which was the same as miR-155 (P<0.05). Moreover, miR-155 slicing and SGK3 overexpression could significantly decrease the painthreshold. The data presented in this study suggested that miR-155 slicing could excellently alleviate neuropathic pain in rats through targeting SGK3 expression. miR-155 may be a potential therapeutic target for neuropathic pain treatment.

R13B1 and R114 exergy-enthalpy charts and their usefulness in a refrigerating-heating process analysis

International Nuclear Information System (INIS)

de Rossi, F.; Mastrullo, R.; Sasso, M.; Sibilio, S.

1989-01-01

R13B1 and R114 exergy-enthalpy diagrams in SI units based on data and equations published by the International Institute of Refrigeration are presented. The charts cover the ranges of 0.5 kPa to 15000 kPa and 120 degrees C to 180 degrees C for R13B1 and 0.8 kPa to 5000 kPa and -70 degrees C to 250 degrees C for R114. In this paper an analysis of a cascade refrigerating-heating compound system is included to illustrate the use of the charts

Evaluation of flurbiprofen in detrusor instability.

OpenAIRE

Cardozo, L D; Stanton, S L; Robinson, H; Hole, D

1980-01-01

Thirty women with detrusor instability (27 cases idiopathic, and three secondary to multiple sclerosis) completed a double-blind, cross-over trial of the prostaglandin synthetase inhibitor flurbiprofen and a placebo, results being evaluated by questionnaire and cystometry. Frequency, urgency, and urge incontinence were all significantly reduced with flurbiprofen (P less than 0.001, P less than 0.025, and P less than 0.025 respectively), as was the detrusor-pressure rise during bladder filling...

EFFECT OF DIFFERENT COMPACTION PRESSURE AND DIFFERENT SINTERING ROUTE ON K0.5NA0.5NBO₃ PHYSICAL AND DIELECTRIC PROPERTIES

Directory of Open Access Journals (Sweden)

Nor Fatin Khairah Bahanurddin

2016-07-01

Full Text Available Alkaline niobate known as K0.5Na0.5NbO3 (KNN, a lead-free piezoelectric ceramic was synthesized via a solid state reaction method. The samples were compacted at different pressures (100, 200, 300 and 400 MPa and sintered using two different techniques (conventional furnace and hot isostatic pressing (HIP. The effect of compaction pressure and sintering technique on physical and dielectric properties was studied. The optimum compaction pressure (300 MPa and sintering via HIP (at 1080 °C for 30 min increased the density and grain size ( range 30 - 300 nm and improved its dielectric properties. Therefore, the combination of suitable compaction pressure and sintering technique has produced larger grain size and higher density of KNN which resulted in outstanding dielectric properties. At room temperature, excellent values of ε r (5517.35 and tan δ (0.954, recorded at 1 MHz were measured for the KNN300HIP sample with highest density (4.4885 g/cm³.

Investigation of structural and electrical properties of (1 - x) Bi0.5Mg0.5TiO3-(x) PbTiO3 ceramic system

International Nuclear Information System (INIS)

Rai, Radheshyam; Sinha, Abinhav; Sharmac, Seema; Sinha, N.K.P.

2009-01-01

[(BiMg 0.5 Ti 0.5 O 3 ) 1-x ][PbTiO 3 ] x (BMT-PT) ceramic powders of different compositions were prepared by solid-state reaction method. X-ray diffraction analysis of the compounds suggest the structural change (rhombohedral to tetragonal) in these ceramics. SEM photographs exhibit the uniform distribution of grains with less porosity. Polarization vs. electric field (P-E) studies show maximum remanent polarization (P r ∼ 7.9 μC/cm 2 ) for composition x = 0.34. The dielectric peaks were found to be broadened that indicates the existence of diffuse phase transition. Diffusivity (γ) study of phase transition in these compounds provided values between 1 and 2 indicating the variation of degree of disorderness in the system.

An Algorithm for Template-Based Prediction of Secondary Structures of Individual RNA Sequences

Czech Academy of Sciences Publication Activity Database

Pánek, Josef; Modrák, Martin; Schwarz, Marek

2017-01-01

Roč. 8, OCT 10 (2017), s. 1-11, č. článku 147. ISSN 1664-8021 R&D Projects: GA ČR GA15-00885S; GA MŠk(CZ) LM2015047 Institutional support: RVO:61388971 Keywords : RNA * secondary structure * homology Subject RIV: EE - Microbiology, Virology OBOR OECD: Microbiology Impact factor: 3.789, year: 2016

Surface expression of metabotropic glutamate receptor variants mGluR1a and mGluR1b in transfected HEK293 cells

Czech Academy of Sciences Publication Activity Database

Kumpošt, Jiří; Syrová, Zdeňka; Kulihová, Lenka; Franková, Daniela; Bologna, J.C.; Hlaváčková, Veronika; Prezeau, L.; Králíková, Michaela; Hrušková, Bohdana; Pin, J. P.; Blahoš, Jaroslav

2008-01-01

Roč. 55, č. 4 (2008), s. 409-418 ISSN 0028-3908 R&D Projects: GA ČR GA303/08/1591; GA AV ČR IAA500390701; GA MŠk(CZ) LC06063 Grant - others:GA ČR(CZ) GA204/05/0920 Program:GA Institutional research plan: CEZ:AV0Z50520514 Keywords : G-proteins * glutamate * receptor Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 3.383, year: 2008

Retinol, carotenoids, and tocopherols in the milk of lactating adolescents and relationships with plasma concentrations.

Science.gov (United States)

de Azeredo, Vilma B; Trugo, Nadia M F

2008-02-01

We determined the concentrations of retinol, carotenoids, and tocopherols in breast milk of adolescents and evaluated their associations with plasma levels and with maternal characteristics (period of lactation, body mass index, age of menarche, and years postmenarche). This was a single cross-sectional survey of retinol, carotenoid, and tocopherol composition of milk and plasma of lactating adolescent mothers (n = 72; 30-120 d postpartum) attending public daycare clinics in Rio de Janeiro, Brazil. Milk and plasma components were analyzed by high-performance liquid chromatography. Nutrient concentrations (micromoles per liter, mean +/- SE) in plasma and milk were, respectively, retinol 2.1 +/- 0.5 and 0.62 +/- 0.44, beta-carotene 0.18 +/- 0.19 and 0.016 +/- 0.017, alpha-carotene 0.05 +/- 0.04 and 0.0035 +/- 0.002, lutein plus zeaxanthin 0.15 +/- 0.11 and 0.025 +/- 0.024, lycopene 0.1 +/- 0.11 and 0.016 +/- 0.025, alpha-tocopherol 10.8 +/- 5.3 and 2.7 +/- 1.8, gamma-tocopherol 2.6 +/- 2.3 and 0.37 +/- 0.15. The milk/plasma molar ratios of retinol and tocopherols were two times higher than those of carotenoids. Significant correlations (P milk and plasma nutrient levels were observed for beta-carotene (r = 0.41), alpha-carotene (r = 0.60), and lutein plus zeaxanthin (r = 0.57), but not for lycopene, retinol, and tocopherols. Nutrient concentrations in plasma and in milk were not associated with the maternal characteristics investigated. Concentrations of the nutrients studied, especially retinol and alpha-tocopherol, in mature milk of lactating adolescents were, in general, lower than in milk of adult lactating women. Milk concentrations were associated with plasma concentrations only for beta-carotene, alpha-carotene, and lutein plus zeaxanthin.

Magnetic behaviour of hydrogenated La_0_._5Ca_0_._5MnO_3

International Nuclear Information System (INIS)

Lal, Ganesh; Punia, Khushboo; Kumar, Sudhish; Jyoti; Dolia, S.N.

2016-01-01

The half doped manganite La_0_._5Ca_0_._5MnO_3 have attracted considerable attention owing to its complex electrical and magnetic properties. This work is focused on the effects of hydrogenation on the magnetic behaviour of La_0_._5Ca_0_._5MnO_3. For hydrogenation the La_0_._5Ca_0_._5MnO_3 sample was annealed in a hydrogen atmosphere at 600°C for 6 hours in a reduction furnace and for reducing hydrogen the sample was heated in air at 600°C for 6 hours in a chamber furnace. Room temperature X-ray diffraction studies confirmed that the hydrogenation and annealing of the sample in air does not affect the single phase orthorhombic structure of La_0_._5Ca_0_._5MnO_3. These observations indicate that magnetic behaviour of La_0_._5Ca_0_._5MnO_3. can be tailored by hydrogenation

Very weak solutions to the rotating Stokes, Oseen and Navier–Stokes problems in weighted spaces

Czech Academy of Sciences Publication Activity Database

Kračmar, S.; Krbec, Miroslav; Nečasová, Šárka; Penel, P.; Schumacher, K.

2016-01-01

Roč. 289, 11-12 (2016), s. 1466-1487 ISSN 0025-584X R&D Projects: GA ČR GA13-00522S; GA ČR(CZ) GAP201/11/1304 Institutional support: RVO:67985840 Keywords : viscous incompressible fluid * flow around rotating rigid body * very weak solution * weighted homogenous Sobolev spaces Subject RIV: BA - General Mathematics Impact factor: 0.742, year: 2016 http://onlinelibrary.wiley.com/doi/10.1002/mana.201400052/abstract?systemMessage=Wiley+Online+Library+will+be+unavailable+on+Saturday+3rd+ September +2016+at+08.30+BST%2F+03%3A30+EDT%2F+15%3A30+SGT+for+5+hours+ and +Sunday+4th+ September +at+10%3A00+BST%2F+05%3A00+EST%2F+17%3A00+SGT+for+1+hour++for+essential+maintenance.+Apologies+for+the+inconvenience

KSC-04PD-0025

Science.gov (United States)

2004-01-01

KENNEDY SPACE CENTER, FLA. -- In the KSC television studio, KSC management and other employees applaud President George W. Bush, who addressed the public and an assembly of government officials at NASA Headquarters as he outlined a new focus and vision for the space agency. Seated in the front row, left to right, are Bill Pickavance vice president and associate program manager of Florida Operations, United Space Alliance (USA) ; Howard DeCastro, vice president and Space Shuttle program manager, USA; Shannon Roberts, with External Affairs; Woodrow Whitlow, KSC deputy director; Bruce Buckingham, assistant to Dr. Whitlow; Lisa Malone, director of External Affairs; and Ken Aguilar, chief, Equal Opportunity office. The President stated his goals for NASAs new mission: Completing the International Space Station, retiring the Space Shuttle orbiters, developing a new crew exploration vehicle, and returning to the moon and beyond within the next two decades. Pres. Bush was welcomed by NASA Administrator Sean OKeefe and Expedition 8 Commander Michael Foale, who greeted him from the International Space Station. Members of the Washington, D.C., audience included astronauts Eileen Collins, Ed Lu and Michael Lopez-Alegria, and former astronaut Gene Cernan.

Laboratory spectra of C-13 ethane

Science.gov (United States)

Kurtz, Joe; Reuter, Dennis C.; Jennings, Donald E.; Hillman, John J.

1991-01-01

The laboratory infrared spectrum of C-13 monosubstituted ethane has been obtained at high resolution (0.0025/cm) using the McMath Fourier transform spectrometer at Kitt Peak National Observatory in May 1990. A preliminary analysis of the nu12 rQ0 branch (substituted species) suggests that its intensity is 1.15 + or - 0.05 times stronger than the equivalent nu9 branch in the normal (C-12)2H6 species. This result leads to a correction of a previously published estimate for the C-12/C-13 ratio in the atmosphere of Jupiter from about 94 to about 106.

[Treatment of macular hematoma complicating AMD by vitrectomy, subretinal r-TPA injection, intravitreal injection of bevacizumab combined with gas tamponade: Report of 4 cases].

Science.gov (United States)

Abboud, M; Benzerroug, M; Milazzo, S

2017-02-01

The occurrence of a subretinal hematoma in age-related macular degeneration (AMD) is a serious complication that can impact the visual prognosis with a poor functional recovery. The management of this complication remains controversial. Several therapeutic methods have been described. We report the results of four patients treated with a protocol combining: vitrectomy, subretinal injection of r-TPA 0.025mg/0.3ml, intravitreal injection of 0.05ml of bevacizumab and retinal tamponade with 20% SF6 gas. Our series consists of four patients with a submacular hematoma complicating AMD, included in succession between October 2013 and October 2014 and treated with the same treatment protocol and by the same surgeon. All patients underwent surgery within eight days after the onset of the macular hematoma. Patients with a consultation period longer than eight days did not undergo this treatment. Face down postoperative positioning was then carried out for seven days by the patients. We observed a shift in the macular hematoma in the four patients, which allowed the identification of secondary neovascularization responsible for the bleeding. The visual acuity improved in three patients from hand motion (HM) preoperatively to 2/10 at one month postoperatively. One patient maintained visual acuity 1/20 during the entire follow-up despite almost complete resorption of the subretinal hematoma. These visual acuities were stable at 6 months postoperatively. Macular subretinal hematoma can cause severe visual loss by several mechanisms. The blood accumulates between the neurosensory retina and the retinal pigment epithelium, which causes a toxic effect on the surrounding tissues, thus resulting in a loss of photoreceptors and cellular destruction in the pigment epithelium and choriocapillaris, evolving into a fibroglial scar. The therapeutic evaluation of this protocol in our series of four patients gives a favorable result. We observed an improvement in visual acuity in 3/4 of

Estimation of Joule heating and its role in nonlinear electrical response of Tb0.5Sr0.5MnO3 single crystal

Science.gov (United States)

Nhalil, Hariharan; Elizabeth, Suja

2016-12-01

Highly non-linear I-V characteristics and apparent colossal electro-resistance were observed in non-charge ordered manganite Tb0.5Sr0.5MnO3 single crystal in low temperature transport measurements. Significant changes were noticed in top surface temperature of the sample as compared to its base while passing current at low temperature. By analyzing these variations, we realize that the change in surface temperature (ΔTsur) is too small to have caused by the strong negative differential resistance. A more accurate estimation of change in the sample temperature was made by back-calculating the sample temperature from the temperature variation of resistance (R-T) data (ΔTcal), which was found to be higher than ΔTsur. This result indicates that there are large thermal gradients across the sample. The experimentally derived ΔTcal is validated with the help of a simple theoretical model and estimation of Joule heating. Pulse measurements realize substantial reduction in Joule heating. With decrease in sample thickness, Joule heating effect is found to be reduced. Our studies reveal that Joule heating plays a major role in the nonlinear electrical response of Tb0.5Sr0.5MnO3. By careful management of the duty cycle and pulse current I-V measurements, Joule heating can be mitigated to a large extent.

A quantum-chemical validation about the formation of hydrogen bonds and secondary interactions in intermolecular heterocyclic systems

Directory of Open Access Journals (Sweden)

Boaz Galdino Oliveira

2009-08-01

Full Text Available We have performed a detailed theoretical study in order to understand the charge density topology of the C2H4O···C2H2 and C2H4S···C2H2 heterocyclic hydrogen-bonded complexes. Through the calculations derived from Quantum Theory of Atoms in Molecules (QTAIM, it was observed the formation of hydrogen bonds and secondary interactions. Such analysis was performed through the determination of optimized geometries at B3LYP/6-31G(d,p level of theory, by which is that QTAIM topological operators were computed, such as the electronic density ρ(r, Laplacian Ñ2ρ(r, and ellipticity ε. The examination of the hydrogen bonds has been performed through the measurement of ρ(r, Ñ2ρ(r and ε between (O···H—C and (S···H—C, whereas the secondary interaction between axial hydrogen atoms Hα and carbon of acetylene. In this insight, it was verified the existence of secondary interaction only in C2H4S···C2H2 complex because its structure is propitious to form multiple interactions.

Polishing, coating and integration of SiC mirrors for space telescopes

Science.gov (United States)

Rodolfo, Jacques

2017-11-01

In the last years, the technology of SiC mirrors took an increasingly significant part in the field of space telescopes. Sagem is involved in the JWST program to manufacture and test the optical components of the NIRSpec instrument. The instrument is made of 3 TMAs and 4 plane mirrors made of SiC. Sagem is in charge of the CVD cladding, the polishing, the coating of the mirrors and the integration and testing of the TMAs. The qualification of the process has been performed through the manufacturing and testing of the qualification model of the FOR TMA. This TMA has shown very good performances both at ambient and during the cryo test. The polishing process has been improved for the manufacturing of the flight model. This improvement has been driven by the BRDF performance of the mirror. This parameter has been deeply analysed and a model has been built to predict the performance of the mirrors. The existing Dittman model have been analysed and found to be optimistic.

On Secondary Control Approaches for Voltage Regulation in DC Microgrids

DEFF Research Database (Denmark)

Peyghami, Saeed; Mokhtari, Hossein; Davari, Pooya

2017-01-01

Centralized or decentralized secondary controller is commonly employed to regulate the voltage drop raised by the primary controller. However, in the case of high capacity MGs and long feeders with much voltage drop on the line resistances, the conventional methods may not guarantee the voltage r...

Electric Field-Induced Large Strain in Ni/Sb-co Doped (Bi0.5Na0.5) TiO3-Based Lead-Free Ceramics

Science.gov (United States)

Li, Liangliang; Hao, Jigong; Xu, Zhijun; Li, Wei; Chu, Ruiqing

2018-02-01

Lead-free piezoelectric ceramics (Bi0.5Na0.5)0.935Ba0.065Ti1- x (Ni0.5Sb0.5) x O3 (BNBT6.5- xNS) have been fabricated using conventional solid sintering technique. The effect of (Ni, Sb) doping on the phase structure and electrical properties of BNBT6.5 ceramics were systematically investigated. Results show that the addition of (Ni, Sb) destroyed the ferroelectric long-range order of BNBT6.5 and shifted the ferroelectric-relaxor transition temperature ( T F-R) down to room temperature. Thus, this process induced an ergodic relaxor phase at zero field in samples with x = 0.005. Under the electric field, the ergodic relaxor phase could reversibly transform to ferroelectric phase, which promotes the strain response with peak value of 0.38% (at 80 kV/cm, corresponding to d 33 * = 479 pm/V) at x = 0.005. Temperature-dependent measurements of both polarization and strain confirmed that the large strain originated from a reversible field-induced ergodic relaxor to ferroelectric phase transformation. The proposed material exhibits potential for nonlinear actuators.

Age-related changes in the rCBF in neonates

International Nuclear Information System (INIS)

Song Wenzhong; Chen Changhui; Chen Mingxi; Xie Hongjun; Zhou Aiqun

2001-01-01

Objective: To study the age-related changes of neonatal regional cerebral blood flow (rCBF) [gestation weeks (GW) and days after birth (DAB)]. Methods: Sixteen neonates who had the normal rCBF determined by 99 Tc m -ethylcysteinate dimer (ECD) SPECT imaging and the normal results in the neurological workup after long term clinical follow-up were divided into preterm neonate group (G1: male 3, female 2, GW 34.8 +- 1.2, DAB 7.2 +- 1.3), full-term younger neonate group (G2: male 3, female 2, GW 39.4 +- 1.4, DAB 4.0 +- 1.7) and full-term older neonate (G3: male 5, female 1, GW 40.0 +- 0.8, DAB 14.2 +- 1.9). The radioactivity uptake ratio of different gray matter regions to thalamic region were calculated by ROI. Results: The primary sensomotoric and occipital radioactivity uptake ratio of G1 (0.66 +- 0.08, 0.56 +- 0.10) were significantly lower compared with that of G2 (0.83 +- 0.10, 0.71 +- 0.08, P < 0.05) and G3 (0.94 +- 0.06, 0.79 +- 0.07, P < 0.01). The middle frontal and parietal radioactivity uptake ratio of G1 (0.50 +- 0.07, 0.56 +- 0.10) were significantly lower compared with G3 (0.60 +- 0.05, P < 0.05, 0.69 +- 0.05, P < 0.05). The rCBF of other gray matter regions tended to increase with GW and DAB. The most obvious difference of images between G1 and G2 was at the primary sensomotoric area. Conclusion: These results show that the difference of rCBF between different groups is clearly related to the neonatal age and sequence of neuro-development of the neonates

Genome-wide identification and characterization of R2R3MYB family in Rosaceae.

Science.gov (United States)

González, Máximo; Carrasco, Basilio; Salazar, Erika

2016-09-01

Transcription factors R2R3MYB family have been associated with the control of secondary metabolites, development of structures, cold tolerance and response to biotic and abiotic stress, among others. In recent years, genomes of Rosaceae botanical family are available. Although this information has been used to study the karyotype evolution of these species from an ancestral genome, there are no studies that treat the evolution and diversity of gene families present in these species or in the botanical family. Here we present the first comparative study of the R2R3MYB subfamily of transcription factors in three species of Rosaceae family (Malus domestica, Prunus persica and Fragaria vesca). We described 186, 98 and 86 non-redundant gene models for apple, peach and strawberry, respectively. In this research, we analyzed the intron-exon structure and genomic distribution of R2R3MYB families mentioned above. The phylogenetic comparisons revealed putative functions of some R2R3MYB transcription factors. This analysis found 44 functional subgroups, seven of which were unique for Rosaceae. In addition, our results showed a highly collinearity among some genes revealing the existence of conserved gene models between the three species studied. Although some gene models in these species have been validated under several approaches, more research in the Rosaceae family is necessary to determine gene expression patterns in specific tissues and development stages to facilitate understanding of the regulatory and biochemical mechanism in this botanical family.

Regulation of turkey myogenic satellite cell migration by MicroRNAs miR-128 and miR-24.

Science.gov (United States)

Velleman, S G; Harding, R L

2017-06-01

Myogenic satellite cells are an adult stem cell responsible for all post-hatch muscle growth in poultry. As a stem cell population, satellite cells are highly heterogeneous, but the origin of this heterogeneity remains unclear. Heterogeneity is, in part, regulated by gene expression. One method of endogenous gene regulation that may contribute to heterogeneity is microRNAs (miRNAs). Two miRNAs previously shown to regulate poultry myogenic satellite cell proliferation and differentiation, miR-128 and miR-24, were studied to determine if they also affected satellite cell migration. Satellite cell migration is an essential step for both proliferation and differentiation. During proliferation, satellite cells will migrate and align to form new myofibers or donate their nuclei to existing myofibers leading to muscle fiber hypertrophy or regeneration. Transient transfection of miRNA specific mimics to each miRNA reduced migration of satellite cells following a cell culture scratch at 72 h of proliferation when the cultures were 90 to 100% confluent. However, only the migration in cells transfected with miR-24 mimics at 24 and 30 h following the scratch was significantly reduced (P ≤ 0.05) to around 70% of the distance migrated by controls. Alternately, transfection with inhibitors specific to miR-128 or miR-24 significantly (P ≤ 0.05) increased migration between 147 and 252% compared to their controls between 24 and 48 h following the scratch. These data demonstrate that miR-128 and miR-24 play a role in myogenic satellite cell migration, which will impact muscle development and growth. © 2016 Poultry Science Association Inc.

Secondary Hypertension

Science.gov (United States)

Secondary hypertension Overview Secondary hypertension (secondary high blood pressure) is high blood pressure that's caused by another medical condition. Secondary hypertension can be caused by conditions that affect your kidneys, ...

Posttreatment with group II metabotropic glutamate receptor agonist 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate is only weakly effective on seizures in immature rats

Czech Academy of Sciences Publication Activity Database

Folbergrová, Jaroslava; Druga, Rastislav; Tsenov, Grygoriy; Haugvicová, Renata; Otáhal, Jakub

2009-01-01

Roč. 1273, - (2009), s. 144-154 ISSN 0006-8993 R&D Projects: GA ČR(CZ) GA309/05/2015; GA ČR GA309/08/0292; GA ČR(CZ) GA304/07/1137 Institutional research plan: CEZ:AV0Z50110509; CEZ:AV0Z50200510 Keywords : DL-homocysteic acid-induced seizures * posttreatment with 2R * 4R-APDC * partial protection Subject RIV: FH - Neuro logy Impact factor: 2.463, year: 2009

Polska a rozbicie Czecho-Słowacji w marcu 1939 r

Czech Academy of Sciences Publication Activity Database

Němeček, Jan

2008-01-01

Roč. 16, - (2008), s. 67-86 ISSN 1233-0558 R&D Projects: GA ČR GA409/05/2380 Institutional research plan: CEZ:AV0Z8015903 Keywords : diplomacy * czechoslovak-polish relations Subject RIV: AB - History

Bipolar ferroelectric fatigue in (K0.5Na0.5)(Nb0.7Ta0.3)O3 ceramics and improved fatigue endurance on addition of ZnO

Science.gov (United States)

Vineetha, P.; Shanmuga Priya, B.; Venkata Saravanan, K.

2018-04-01

Ferroelectric ceramics are the key components in piezoelectric devices used today, thus long term reliability is a major industrial concern. The two important things that have to be considered in the ferroelectric material based device are aging and fatigue. The first one describes degradation with time whereas the later one is characterized by the change of material property during electrical loading. In the present work ferroelectric polarization and bipolar fatigue properties of undoped and ZnO doped lead free (K0.5Na0.5)(Nb0.7Ta0.3)O3 (KNNT) ceramics prepared by solid state reaction method were investigated. X-ray diffraction analysis of the samples reveal perovskite monoclinic phase along with the secondary phase of K2Nb4O11. The ferroelectric studies indicate that ZnO addition reduce fatigue as well as a well saturated hysteresis loop is obtained. The results reveal that addition of ZnO enhances the ferroelectric properties of KNNT ceramics.

Improved ferroelectric and photoluminescence properties in Pr3+ substituted Na0.5Bi0.5TiO3 synthesized using hydrothermal route

Science.gov (United States)

Goutham, Cilaveni; Kandula, Kumara Raja; Raavi, Sai Santhosh Kumar; Asthana, Saket

2018-04-01

Nanocrystalline Pr3+ substituted NBT was synthesized using hydrothermal technique. Pr3+ modifies the ferroelectric NBT optically active and enhances the electrical properties with small structural changes. Aiming to the development of the bottom up optoelectronic devices this optimized nanoscale Na0.5Bi0.5-xPrxTiO3(x = 0.005) compound is synthesized hydrothermally. X-ray diffraction pattern shows that the system is stabilized in the Rhombohedral (space groupR3c) phase indicating the local strain inhomogeneity. PE loop shows that there is a decrement in the Ec value compared with compounds synthesized using conventional methods. The strong red emission assigned to prominent transition of the Pr3+ ions at 610nm was observed along with weak blue-green emission, indicating the potential use of the system. Energy transfer from host system to Pr3+ ions is responsible for red emission while blue green emission is due to quenching of 3P0 induced by intervalence charge transfer state.

Crystal and magnetic study of the disordered perovskites Ca(Mn0.5Sb0.5)O3 and Ca(Fe0.5Sb0.5)O3

International Nuclear Information System (INIS)

Retuerto, M.; Martinez-Lope, M.J.; Garcia-Hernandez, M.; Munoz, A.; Fernandez-Diaz, M.T.; Alonso, J.A.

2010-01-01

We have investigated the double perovskites Ca 2 MSbO 6 (M = Mn, Fe) that have been prepared by solid-state reaction (M = Fe) and wet chemistry procedures (M = Mn). The crystal and magnetic structures have been studied from X-ray (XRD) and neutron powder diffraction (NPD) data. Rietveld refinements show that the crystal structures are orthorhombic (space group Pbnm) with complete disorder of M and Sb cations, so the formula should be rewritten as Ca(M 0.5 Sb 0.5 )O 3 . Due to this disorder no evidences of Jahn-Teller distortion can be observed in the MnO 6 octahedra of Ca(Mn 0.5 Sb 0.5 )O 3 , in contrast with the ordered double perovskite Sr 2 MnSbO 6 . Ca(Fe 0.5 Sb 0.5 )O 3 behaves as an antiferromagnet with an ordered magnetic moment for Fe 3+ of 1.53(4)μ B and a propagation vector k = 0, as investigated by low-temperature NPD. The antiferromagnetic ordering is a result of the high degree of Fe/Sb anti-site disorder of the sample, which originates the spontaneous formation of Fe-rich islands, characterized by the presence of strong Fe-O-Fe antiferromagnetic couplings with enough long-range coherence to produce a magnetic contribution perceptible by NPD. By contrast, the magnetic structure of Ca(Mn 0.5 Sb 0.5 )O 3 cannot be observed by low-temperature NPD because the magnitude of the ordered magnetic moments is below the detection threshold for neutrons.

Secondary Hyperparathyroidism and Bone Turnover in Elderly with Bone Loss - Original Investigation

Directory of Open Access Journals (Sweden)

Nurdan Peker

2006-12-01

Full Text Available Bone loss is common in the elderly. Parathyroid hormone (PTH, which regulates serum calcium levels,calcitonin and vitamin D metabolites have various effects on skeletal system. The aim of this study was to assess secondary hyperparathyroidism (HPTH and bone turnover in elderly with bone loss. Fifty-five patients (9 men,46 women older than 65 years with bone loss were included in the study. Bone mineral density was measured by dual energy x-ray absorptiomety (DXA at L1-4 vertebrae and proximal femur regions. Patients with T scores <-1.5 at one of the measurement sites were included in the study. Study subjects were assessed in terms of fracture history, sunbathing and walking activity. Routine biochemical tests, serum osteocalcin (OC and C-telopeptide type 1 collagen (CTX and lateral thoracal and lumbar vertebrae radyographic evaluation was performed. Our results showed that 70.9% of the patients had HPTH. Total femur BMD values and femur neck T scores were significantly lower in HPTH group than PTH normal one (p=0.05, p=0.03. Serum OC and CTX levels were higher in both groups. There was a negative correlation with femur neck BMD and CTX (r=0,321. There was no correlation between serum PTH levels and lumbar vertebrae and proximal femur BMD values. Serum PTH and alkaline phosphatase levels showed a significant positive correlation. In conclusion secondary HPTH and increased bone turnover is common elderly with bone loss. Adequate calcium and vitamin D intake is important the older people. (Osteoporoz Dünyasından 2006; 12: 70-3

[Atmospheric emission of PCDD/Fs from secondary aluminum metallurgy industry in the southwest area, China].

Science.gov (United States)

Lu, Yi; Zhang, Xiao-Ling; Guo, Zhi-Shun; Jian, Chuan; Zhu, Ming-Ji; Deng, Li; Sun, Jing; Zhang, Qin

2014-01-01

Five secondary aluminum metallurgy enterprises in the southwest area of China were measured for emissions of PCDD/Fs. The results indicated that the emission levels of PCDD/Fs (as TEQ) were 0.015-0.16 ng x m(-3), and the average was 0.093 ng x m(-3) from secondary aluminum metallurgy enterprises. Emission factors of PCDD/Fs (as TEQ) from the five secondary aluminum metallurgy enterprises varied between 0.041 and 4.68 microg x t(-1) aluminum, and the average was 2.01 microg x t(-1) aluminum; among them, PCDD/Fs emission factors from the crucible smelting furnace was the highest. Congener distribution of PCDD/F in stack gas from the five secondary aluminum metallurgies was very different from each other. Moreover, the R(PCDF/PCDD) was the lowest in the enterprise which was installed only with bag filters; the R(PCDF/PCDD) were 3.8-12.6 (the average, 7.7) in the others which were installed with water scrubbers. The results above indicated that the mechanism of PCDD/Fs formation was related to the types of exhaust gas treatment device. The results of this study can provide technical support for the formulation of PCDD/Fs emission standards and the best available techniques in the secondary aluminum metallurgy industry.

Diversity of 23S rRNA genes within individual prokaryotic genomes.

Directory of Open Access Journals (Sweden)

Anna Pei

Full Text Available BACKGROUND: The concept of ribosomal constraints on rRNA genes is deduced primarily based on the comparison of consensus rRNA sequences between closely related species, but recent advances in whole-genome sequencing allow evaluation of this concept within organisms with multiple rRNA operons. METHODOLOGY/PRINCIPAL FINDINGS: Using the 23S rRNA gene as an example, we analyzed the diversity among individual rRNA genes within a genome. Of 184 prokaryotic species containing multiple 23S rRNA genes, diversity was observed in 113 (61.4% genomes (mean 0.40%, range 0.01%-4.04%. Significant (1.17%-4.04% intragenomic variation was found in 8 species. In 5 of the 8 species, the diversity in the primary structure had only minimal effect on the secondary structure (stem versus loop transition. In the remaining 3 species, the diversity significantly altered local secondary structure, but the alteration appears minimized through complex rearrangement. Intervening sequences (IVS, ranging between 9 and 1471 nt in size, were found in 7 species. IVS in Deinococcus radiodurans and Nostoc sp. encode transposases. T. tengcongensis was the only species in which intragenomic diversity >3% was observed among 4 paralogous 23S rRNA genes. CONCLUSIONS/SIGNIFICANCE: These findings indicate tight ribosomal constraints on individual 23S rRNA genes within a genome. Although classification using primary 23S rRNA sequences could be erroneous, significant diversity among paralogous 23S rRNA genes was observed only once in the 184 species analyzed, indicating little overall impact on the mainstream of 23S rRNA gene-based prokaryotic taxonomy.

Mental Health and Adjustment of Higher Secondary School Students

Science.gov (United States)

Murugan, P. Vel

2017-01-01

The main objective of this study is to find out the relationship between mental health and adjustment of higher secondary school students. Mental Health Scale developed by Sakthimani (2010) and Adjustment Inventory developed by A.K.P. Sinha and R.P. Singh (2007) were used to collect the relevant data. The sample consists of 103 higher secondary…

Spatial characteristics of secondary flow in a turbulent boundary layer over longitudinal surface roughness

Science.gov (United States)

Hwang, Hyeon Gyu; Lee, Jae Hwa

2017-11-01

Direct numerical simulations of turbulent boundary layers (TBLs) over spanwise heterogeneous surface roughness are performed to investigate the characteristics of secondary flow. The longitudinal surface roughness, which features lateral change in bed elevation, is described by immersed boundary method. The Reynolds number based on the momentum thickness is varied in the range of Reθ = 300-900. As the TBLs over the roughness elements spatially develop in the streamwise direction, a secondary flow emerges in a form of counter-rotating vortex pair. As the spanwise spacing between the roughness elements and roughness width vary, it is shown that the size of the secondary flow is determined by the valley width between the roughness elements. In addition, the strength of the secondary flow is mostly affected by the spanwise distance between the cores of the secondary flow. Analysis of the Reynolds-averaged turbulent kinetic energy transport equation reveals that the energy redistribution terms in the TBLs over-the ridge type roughness play an important role to derive low-momentum pathways with upward motion over the roughness crest, contrary to the previous observation with the strip-type roughness. This research was supported by the National Research Foundation of Korea (NRF) funded by the Ministry of Education (NRF-2017R1D1A1A09000537) and the Ministry of Science, ICT & Future Planning (NRF-2017R1A5A1015311).

Impedance spectroscopy study and phase transition in phospho-vanadium mixed oxide LiZnV{sub 0.5}P{sub 0.5}O{sub 4}

Energy Technology Data Exchange (ETDEWEB)

Rahal, A.; Guidara, Kamel; Megdiche, Makram [Sfax Universite, Laboratoire de Caracterisations Spectroscopiques et Optique des Materiaux (LaSCOM), Faculte des Sciences de Sfax, BP 1171, Sfax (Tunisia); Megdiche Borchani, S. [Sfax Universite, Laboratoire de Caracterisations Spectroscopiques et Optique des Materiaux (LaSCOM), Faculte des Sciences de Sfax, BP 1171, Sfax (Tunisia); Institut Superieur D' Informatique et de Multimedia de Sfax (ISIMS), Pole Technologique de Sfax, Sakiet Ezzit, BP 242, Sfax (Tunisia)

2017-08-15

An X-ray crystallographic study has allowed us to identify a powder of the type LiZnV{sub 0.5}P{sub 0.5}O{sub 4}, which contains 50% of vanadium and 50% of phosphor, inside the binary system LiZnVO{sub 4}-LiZnPO{sub 4}. The structure is isotypic with the phenacite like LiZnP0{sub 4}. X-ray diffraction patterns are indexed according to the lattice parameters of the rhombohedral system and the R3 space group. IR spectra show the presence of VO{sub 4} and PO{sub 4} groups in the network of this material. The experimental results indicate that σ{sub AC}(ω) is proportional to (ω{sup n}). The activation energy found from the Arrhenius plot confirms that the conduction processing of the material is not due to simple hopping mechanism. The temperature dependence of frequency exponent n was investigated to understanding the conduction mechanism in LiZnV{sub 0.5}P{sub 0.5}O{sub 4}. The non-overlapping small Polaron tunneling (NSPT) model can explain the temperature dependence of the frequency exponent. A phase transition at T = 623 K has been evidenced by Differential scanning calorimetry (DSC) and subsequently confirmed by the analysis of dielectric and electric properties. (orig.)

Příčiny bezdomovství v ČR

Czech Academy of Sciences Publication Activity Database

Mikeszová, Martina

2011-01-01

Roč. 9, č. 5 (2011), s. 2-4 ISSN 1214-1720 R&D Projects: GA MMR WD-05-07-3 Institutional research plan: CEZ:AV0Z70280505 Keywords : homelessness * housing * poverty Subject RIV: AO - Sociology, Demography http://www.socioweb.cz/upl/editorial/download/190_SOCIOWEB_05_2011.pdf

NCBI nr-aa BLAST: CBRC-RNOR-05-0237 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-RNOR-05-0237 ref|NP_001832.1| cannabinoid receptor 2 (macrophage) [Homo sapien...s] sp|P34972|CNR2_HUMAN Cannabinoid receptor 2 (CB2) (CB-2) (CX5) emb|CAA52376.1| CB2 (peripheral) cannabino...id receptor [Homo sapiens] emb|CAD22548.1| peripheral cannabinoid receptor CB2 [Homo sapiens] emb|CAD22549.1| peripheral cann...abinoid receptor CB2 [Homo sapiens] gb|AAO92299.1| cannabinoid r...eceptor 2 [Homo sapiens] emb|CAI14799.1| cannabinoid receptor 2 (macrophage) [Homo sapiens] emb|CAJ42137.1| cann

An intergenic non-coding rRNA correlated with expression of the rRNA and frequency of an rRNA single nucleotide polymorphism in lung cancer cells.

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Yih-Horng Shiao

Full Text Available BACKGROUND: Ribosomal RNA (rRNA is a central regulator of cell growth and may control cancer development. A cis noncoding rRNA (nc-rRNA upstream from the 45S rRNA transcription start site has recently been implicated in control of rRNA transcription in mouse fibroblasts. We investigated whether a similar nc-rRNA might be expressed in human cancer epithelial cells, and related to any genomic characteristics. METHODOLOGY/PRINCIPAL FINDINGS: Using quantitative rRNA measurement, we demonstrated that a nc-rRNA is transcribed in human lung epithelial and lung cancer cells, starting from approximately -1000 nucleotides upstream of the rRNA transcription start site (+1 and extending at least to +203. This nc-rRNA was significantly more abundant in the majority of lung cancer cell lines, relative to a nontransformed lung epithelial cell line. Its abundance correlated negatively with total 45S rRNA in 12 of 13 cell lines (P = 0.014. During sequence analysis from -388 to +306, we observed diverse, frequent intercopy single nucleotide polymorphisms (SNPs in rRNA, with a frequency greater than predicted by chance at 12 sites. A SNP at +139 (U/C in the 5' leader sequence varied among the cell lines and correlated negatively with level of the nc-rRNA (P = 0.014. Modelling of the secondary structure of the rRNA 5'-leader sequence indicated a small increase in structural stability due to the +139 U/C SNP and a minor shift in local configuration occurrences. CONCLUSIONS/SIGNIFICANCE: The results demonstrate occurrence of a sense nc-rRNA in human lung epithelial and cancer cells, and imply a role in regulation of the rRNA gene, which may be affected by a +139 SNP in the 5' leader sequence of the primary rRNA transcript.

ANALISIS PERBANDINGAN EVAPORATOR KULKAS (LEMARI ES DENGAN MENGUNAKAN REFRIGERANT R-22 DAN R-134A

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Imam Faozan

2017-03-01

Full Text Available Tulisan ini bertujuan untuk mengetahui komponen mesin refrigerasi khususnya pembahasan evaporator. Dalam penelitian ini digunakan lemari pendingin (kulkas sederhana untuk pengawetan dan pendinginan bahan makanan dalam rumah tangga. Untuk refrigerant yang digunakan adalah Refrigerant Freon  R – 22 dan  Freon R - 134a sebagai perbandingan dan untuk mengetahui performance evaporator ( COP pada mesin refrigerasi untuk rumah tangga. Lemari pendingin yang dianalisa berukuran tinggi  = 1 m, panjang  = 0,55 m  dan lebar 0,5 m. Temperatur evaporasi = -5°C dan temperature kondensasi = 40°C.

Prokaryotic and eukaryotic features observed on the secondary structures of Giardia SSU rRNAs and its phylogenetic implications.

Science.gov (United States)

Hwang, Ui Wook

2007-04-01

Phylogenetic position of a diplomonad protist Giardia, a principle cause of diarrhea, among eukaryotes has been vigorously debated so far. Through the comparisons of primary and secondary structures of SSU rRNAs of G. intestinalis, G. microti, G. ardeae, and G. muris, I found two major indel regions (a 6-nt indel and a 22-26-nt indel), which correspond to the helix 10 of the V2 region and helices E23-8 to E23-9 of the V4 region, respectively. As generally shown in eukaryotes, G. intestinalis and G. microti have commonly a relatively longer helix 10 (a 7-bp stem and a 4-nt loop), and also the eukaryote-specific helices E23-6 to E23-9. On the other hand, G. muris and G. ardeae have a shorter helix 10: a 2-bp stem and a 6-nt loop in G. ardeae and a 3-bp stem and a 6-nt loop in G. muris. In the V4, they have a single long helix (like the P23-1 helix in prokaryotes) instead of the helices E23-6 to E23-9. Among the four Giardia species, co-appearance of prokaryote- and eukaryote-typical features might be significant evidence to suggest that Giardia (Archezoa) is a living fossil showing an "intermediate stage" during the evolution from prokaryotes to eukaryotes.

Secondary phases in Al_xCoCrFeNi high-entropy alloys: An in-situ TEM heating study and thermodynamic appraisal

International Nuclear Information System (INIS)

Rao, J. C.

2017-01-01

Secondary phases, either introduced by alloying or heat treatment, are commonly present in most high-entropy alloys (HEAs). Understanding the formation of secondary phases at high temperatures, and their effect on mechanical properties, is a critical issue that is undertaken in the present paper, using the Al_xCoCrFeNi (x = 0.3, 0.5, and 0.7) as a model alloy. The in-situ transmission-electron-microscopy (TEM) heating observation, an atom-probe-tomography (APT) study for the reference starting materials (Al_0_._3 and Al_0_._5 alloys), and thermodynamic calculations for all three alloys, are performed to investigate (1) the aluminum effect on the secondary-phase fractions, (2) the annealing-twinning formation in the face-centered-cubic (FCC) matrix, (3) the strengthening effect of the secondary ordered body-centered-cubic (B2) phase, and (4) the nucleation path of the σ secondary phase thoroughly. Finally, the present work will substantially optimize the alloy design of HEAs and facilitate applications of HEAs to a wide temperature range.

Sorption of uranium and cesium by Hanford basalts and associated secondary smectite

International Nuclear Information System (INIS)

Ames, L.L.; McGarrah, J.E.; Walker, B.A.; Salter, P.F.

1982-01-01

Three characterized basalts and an associated secondary smectite were used in comparative uranium and cesium sorption studies. Experiments utilizing two synthetic characteristic basalt groundwaters at 23 and 60 0 C allowed comparison of increased temperature and carbonate concentration effects on Cs and U sorption. The sorption data were fitted to the Dubinin-Radushkevich (D-R) isotherm, and loading maxima and energetics derived. An increase in temperature caused a decrease in Cs sorption maxima on all solids from all groundwaters studied and an increase in U sorption maxima, especially from the higher-carbonate-content groundwater. Sorption energies were characteristic of ion exchange for both Cs and U sorption processes. Basalt U sorption maxima were relatively insignificant, but smectite U sorption maxima surpassed Cs sorption maxima in both groundwaters at 60 0 C. The uranyl carbonate complexes thus may be relatively temperature-sensitive. Upon removal of excess Fe-oxides from the secondary smectite, U sorption decreased and the D-R isotherm reverted to a normal Freundlich sorption isotherm. Removal of excess Fe-oxides from the basalts and secondary smectite would probably result in Freundlich sorption isotherms for both Cs and U. (Auth.)

A Cross-sectional study to look at the determinants of poor adherence to secondary penicillin prophylaxis for rheumatic heart disease at a tertiary care center in South India

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Lalita Nemani

2018-01-01

Full Text Available Background: Rheumatic heart disease (RHD continues to create havoc in the developing countries even decades after its discovery. It is entirely preventable through primordial, primary, and secondary level intervention. Secondary prevention is a reasonable treatment option in patients in India, but it suffers due to poor adherence which remains the main impediment to its implementation. The aim is to study the compliance with benzathine penicillin as secondary prophylaxis in RHD patients and to establish the patient-related factors for adherence and reasons for missing of doses. Materials and Methods: This is a cross-sectional study of RHD patients presenting to our institute. The demographic data, clinical history, and details of penicillin prophylaxis were noted. The patient was labeled as compliant or noncompliant depending on frequency and duration of prophylaxis as prescribed. Potential factors between the two groups have been analyzed by univariate and binary logistic regression. Results: The study cohort of 500 patients consisted of 261 compliant and 239 noncompliant patients. Average age of presentation was 29 ± 13 years with females outnumbering the males. Noncompliance with secondary prophylaxis was more prevalent among male (P = 0.003, low socioeconomic class (P = 0.0009, uneducated (P = 0.000018, and the rural population (P = 0.025 while those with previous history of rheumatic fever (RF were found to be more compliant (P = 0.04. Recurrences of RF were more common in those not on regular prophylaxis (P = 0.011. The most common reason cited for noncompliance was the absence of proper counseling followed by a sense of well-being, injection site pain and financial constraints. Conclusion: Compliance with secondary penicillin prophylaxis is essential to ensure eradication of RHD. Education about the importance and necessity of prophylaxis would improve compliance. A close patient and health personnel relationship is important in

Enhanced photocatalytic properties of ZnO/reduced graphene oxide sheets (rGO) composites with controllable morphology and composition

Energy Technology Data Exchange (ETDEWEB)

Zhao, Yanting, E-mail: 928221565@qq.com; Liu, Lin, E-mail: llspzjnu@163.com; Cui, Tingting, E-mail: wuleiwangyou@163.com; Tong, Guoxiu, E-mail: tonggx@zjnu.cn; Wu, Wenhua, E-mail: tongwu@zjnu.cn

2017-08-01

Highlights: • An easy one-step low-temperature chemical etching route for ZnO NR/rGO composites. • Modulation over the ZnO morphology and content in ZnO NR/rGO composites. • Investigating shape and content-dependent optical and photocatalytic properties. • Revealing the enhancement mechanism of optical and photocatalytic properties. - Abstract: ZnO with various morphologies and contents was used to decorate reduced graphene oxide (rGO) sheets via an easy one-step low-temperature chemical etching route to improve photocatalytic properties. The ZnO shape and content in ZnO/rGO composites were adjusted by changing aging time, heating mode, and rGO mass added. Shape and content-dependent optical and photocatalytic properties are observed in ZnO/rGO composites. A moderate amount of ZnO nanorings (NRs) decorated with rGO can significantly improve the light absorption and photo-luminescence emission because of plasmonic resonant absorption and plasmonic nanoantenna radiation, respectively. ZnO NR/rGO composites with a moderate ZnO content of 29.54 wt.% exhibit the optimum photocatalytic activity with a 0.025 min{sup −1} apparent rate constant, which is significantly higher than those of pure rGO (0.0085 min{sup −1}) and ZnO NRs (0.018 min{sup −1}). The improved performance is ascribed to the synergistic effect of enhanced adsorption capacity, plasmonic light absorption, plasmonic nanoantenna radiation, and the prolonged lifetime of photogenerated electron-hole pairs. Our findings not only offer insights into the plasmon enhanced optical and photocatalytic properties of ZnO NR/rGO composites but also suggest the possibility of fabricating ZnO NR/rGO photocatalyst with enhanced performance.

The characteristic of rBMD distribution in lumbar vertebral body

International Nuclear Information System (INIS)

Wang Chenguang; Xiao Xiangsheng; Chen Xingrong; Shen Tianzhen; Liu Guanghua; Hong Qingjian; Ji Rongming; Zhou Weiming

1998-01-01

Purpose: To determine the distribution and variation of rBMD in human lumbar vertebral body. Methods: The BMD and rBMD of 28 samples of lumbar body were measured with QCT. The rBMD was measured in the regions of anterior, anterolateral, posterolateral and central, superior-level, middle-level and inferior-level of the vertebral bodies. The relationship between BMD and rBMD were statistically analysed with multiple regression. Results: The rBMD of the inferior vertebral body was higher than that of the superior and middle portions (P<0.05); the central and posterolateral higher than the anterior and anterolateral (P<0.05). The rBMD of posterioinferior vertebral body was the highest. The multiple regression showed that the standard partial regression coefficient of inferior was larger than the superior and middle; the anterior and central were larger than the other regions of the vertebra. Variations of the BMD of vertebral body were mostly related to the rBMD of anterior and central parts. Conclusion: The distribution of BMD are heterogeneous in vertebral body. The anterior and central part of vertebral body are most sensitive to bone loss in osteoporosis. It is emphasized that the rBMD of anterior and central part of vertebral body should be measured for following the osteoporosis

Use of Aloe vera shell ash supported Ni0.5Zn0.5Fe2O4 magnetic nanoparticles for removal of Pb (II from aqueous solutions

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Samira Namavari

2016-03-01

Full Text Available Background: Lead (Pb is a heavy metal that is widely utilized in industries. It contaminates soil and groundwater. Its non-biodegradability, severe toxicity, carcinogenicity, ability to accumulate in nature and contaminate groundwater and surface water make this toxic heavy metal extremely dangerous to living beings and the environment. Therefore, technical and economic methods of removing Pb are of great importance. This study evaluated the efficiency of Ni0.5Zn0.5Fe2O4 magnetic nanoparticles supported by Aloe vera shell ash in removing Pb from aqueous environments. Methods: The adsorbent was characterized by several methods, including x-ray diffraction (XRD, scanning electron microscopy (SEM, and Fourier transform infrared spectroscopy (FT-IR. Then, the potential of Aloe vera shell ash-supported Ni0.5Zn0.5Fe2O4 magnetic nanoparticles to adsorb Pb (II was investigated. To determine the amount of lead absorbed by this adsorbent, different pHs (2, 4, 5, and 6, adsorbent doses (0.01-0.40 g, Pb concentrations (5, 10, 20, 30, 40, 50, 60, 80, 100, 200, 300, and 600 mg/L, and exposure times (0, 5, 10, 15, 20, 30, 40, 50, and 60 minutes until reaching equilibrium were tested using an atomic absorption spectrometer (Varian-AA240FS. Residual concentrations of Pb were read. Results: The results show that a time of 15 minutes, pH value of 9, and adsorbent dose of 0.2 g are the optimum conditions for Pb (II removal by this adsorption process. Increasing the initial concentration of Pb (II from 5 to 600 mg/L decreased removal efficiency from 98.8% to 73%. The experimental data fit well into the Freundlich isotherm model (R2 = 0.989. Conclusion: Ni0.5Zn0.5Fe2O4 magnetic nanoparticles supported by Aloe vera shell ash comprise a low-cost, simple, and environmentally benign procedure. The maximum monolayer adsorption capacity based on the Langmuir isotherm (R2 = 0.884 is 47.2 mg g-1. The prepared magnetic adsorbent can be well dispersed in aqueous solutions and

School Dropout Pattern among Senior Secondary Schools in Delta State, Nigeria

Science.gov (United States)

Ajaja, O. Patrick

2012-01-01

The major purpose of this study was to determine the pattern of dropout among secondary school students in Delta State. To guide this study, 7 research questions were asked and answered, 3 hypotheses stated and tested at 0.05 level of significance. The design of study was ex post facto using the past school attendance registers as the major…

Microstructural and electrical properties of (La0.5-xPrxBa0.5)(Mn0.5Ti0.5)O3 perovskite

International Nuclear Information System (INIS)

Nor Hayati Alias; Abdul Halim Shaari; Wan Mohd Daud Wan Yusoff; Che Seman Mahmood

2009-01-01

Full text: A single phase new perovskite based titanio-manganite (La 0.5-x Pr x Ba 0.5 )(Mn 0.5 Ti 0.5 )O 3 has been successfully prepared by ceramic C. The concentration of solid-state technique at sintering temperature of 1300 Pr (Praseodymium), x, in molar proportion in A site has been varied as x = 0.0, 0.2 and 0.02. Analysis has been carried out to determine the electrical properties of the synthesized material at frequency of 1 MHz and at temperature range between 25 to 200 degree Celsius. It is found that Pr addition promoted liquid sintering diffusion, porosity and agglomeration formation at 1300 degree Celsius. Dual relaxation is observed in unsubstituted Pr sample x = 0 and high Pr substituted sample x=0.2. This phenomenon was a combinational contribution from a quasi dc (QDC) low frequency dispersion and two cole-cole relaxational response. While low concentrated Pr substituted sampled x=0.02 shows a combinational contribution from a quasi dc (QDC) low frequency dispersion and single cole-cole relaxational response at room temperature. Pr substitution at x=0 and x=0.2 showed high dielectric values compared to low substituted sample x = 0.02. Variation of dielectric loss tangent (tan ) are observed for all samples at temperature ranged studied. (author)

Gd3+ doped Mn-Zn soft ferrite nanoparticles: Superparamagnetism and its correlation with other physical properties

International Nuclear Information System (INIS)

Thakur, Prashant; Sharma, Rohit; Sharma, Vineet; Barman, P.B.; Kumar, Manoj; Barman, Dipto; Katyal, S.C.; Sharma, Pankaj

2017-01-01

Highlights: • Superparamagnetic nanoparticles of Gd doped Mn-Zn spinel ferrites synthesized by co-precipitation. • XRD and FTIR studies justify the formation of cubical spinel structure. • Maximum saturation magnetization and magnetic moment at x = 0.025. • PL spectra shows blue shift for x = 0.025, 0.075 and may be attributed to quantum confinement. - Abstract: Superparamagnetic nanoparticles are very important in biomedicine due to their various applications like drug delivery, gene delivery in the body and also used for hyperthermia. In the present work, superparamagnetic nanoparticles of Mn 0.5 Zn 0.5 Gd x Fe 2-x O 4 (x = 0, 0.025, 0.050, 0.075, 0.1) ferrites have been prepared by co-precipitation method. Thorough characterizations (XRD, FTIR, FE-SEM, EDS, VSM and fluorescence spectroscopy) have proved the formation of cubical spinel superparamagnetic nanoparticles of soft ferrites. A cation distribution has been proposed for the determination of various important theoretical parameters for these samples. With the addition of Gd 3+ nanoparticles have shown the superparamagnetism at room temperature confirmed by VSM analysis. Photoluminescence (PL) spectra shows a blue shift (for x = 0.025, 0.075) which may be due to quantum confinement.

Turmeric (Curcuma longa): miRNAs and their regulating targets are involved in development and secondary metabolite pathways.

Science.gov (United States)

Singh, Noopur; Sharma, Ashok

Turmeric has been used as a therapeutic herb over centuries in traditional medicinal systems due to the presence of several secondary metabolite compounds. microRNAs are known to regulate gene expression at the post-transcriptional level by transcriptional cleavage or translation repression. miRNAs have been demonstrated to play an active role in secondary metabolism regulation. The present work was focused on the identification of the miRNAs involved in the regulation of secondary metabolite and development process of turmeric. Eighteen miRNA families were identified for turmeric. Sixteen miRNA families were observed to regulate 238 target transcripts. LncRNAs targets of the putative miRNA candidates were also predicted. Our results indicated their role in binding, reproduction, stress, and other developmental processes. Gene annotation and pathway analysis illustrated the biological function of the targets regulated by the putative miRNAs. The miRNA-mediated gene regulatory network also revealed co-regulated targets that were regulated by two or more miRNA families. miR156 and miR5015 were observed to be involved in rhizome development. miR5021 showed regulation for terpenoid backbone biosynthesis and isoquinoline alkaloid biosynthesis pathways. The flavonoid biosynthesis pathway was observed to be regulated by miR2919. The analysis revealed the probable involvement of three miRNAs (miR1168.2, miR156b and miR1858) in curcumin biosynthesis. Other miRNAs were found to be involved in the growth and developmental process of turmeric. Phylogenetic analysis of selective miRNAs was also performed. Copyright © 2017 Académie des sciences. Published by Elsevier Masson SAS. All rights reserved.

Characterizing cross-professional collaboration in research and development projects in secondary education

NARCIS (Netherlands)

Schenke, W.; van Driel, J.H.; Geijsel, F.P.; Sligte, H.W.; Volman, M.L.L.

2016-01-01

Collaboration between practitioners and researchers can increasingly be observed in research and development (R&D) projects in secondary schools. This article presents an analysis of cross-professional collaboration between teachers, school leaders and educational researchers and/or advisers as part

Diuretics, calciuria and secondary hyperparathyroidism in the Chronic Renal Insufficiency Cohort

Science.gov (United States)

Isakova, Tamara; Anderson, Cheryl A. M.; Leonard, Mary B.; Xie, Dawei; Gutiérrez, Orlando M.; Rosen, Leigh K.; Theurer, Jacquie; Bellovich, Keith; Steigerwalt, Susan P.; Tang, Ignatius; Anderson, Amanda Hyre; Townsend, Raymond R.; He, Jiang; Feldman, Harold I.; Wolf, Myles

2011-01-01

Background. Secondary hyperparathyroidism is a common complication of chronic kidney disease (CKD) that is associated with bone disease, cardiovascular disease and death. Pathophysiological factors that maintain secondary hyperparathyroidism in advanced CKD are well-known, but early mechanisms of the disease that can be targeted for its primary prevention are poorly understood. Diuretics are widely used to control volume status and blood pressure in CKD patients but are also known to have important effects on renal calcium handling, which we hypothesized could alter the risk of secondary hyperparathyroidism. Methods. We examined the relationship of diuretic treatment with urinary calcium excretion, parathyroid hormone (PTH) levels and prevalence of secondary hyperparathyroidism (PTH ≥ 65 pg/mL) in a cross-sectional study of 3616 CKD patients in the Chronic Renal Insufficiency Cohort. Results. Compared with no diuretics, treatment with loop diuretics was independently associated with higher adjusted urinary calcium (55.0 versus 39.6 mg/day; P secondary hyperparathyroidism (odds ratio 2.1; 95% CI 1.7–2.6). Thiazide monotherapy was associated with lower calciuria (25.5 versus 39.6 mg/day; P hyperparathyroidism (odds ratio 1.3 versus 2.1; P for interaction = 0.05) compared with loop diuretics alone. Conclusions. Loop diuretic use was associated with greater calciuria, PTH levels and odds of secondary hyperparathyroidism compared to no treatment. These associations were attenuated in patients who were coadministered thiazides. Diuretic choice is a potentially modifiable determinant of secondary hyperparathyroidism in CKD. PMID:21382989

Valence behavior of Eu-ions in intermetallic compound Ce{sub 0.5}Eu{sub 0.5}Pd{sub 3}B{sub 0.5}

Energy Technology Data Exchange (ETDEWEB)

Pandey, Abhishek, E-mail: apandey@ameslab.gov [Experimental Condensed Matter Physics Division, Saha Institute of Nuclear Physics, 1/AF, Bidhannagar, Kolkata 700064 (India); S.N. Bose National Centre for Basic Sciences, Block-JD, Sector-III, Salt Lake, Kolkata 700098 (India); Mazumdar, Chandan, E-mail: chandan.mazumdar@saha.ac.in [S.N. Bose National Centre for Basic Sciences, Block-JD, Sector-III, Salt Lake, Kolkata 700098 (India); Ranganathan, R. [S.N. Bose National Centre for Basic Sciences, Block-JD, Sector-III, Salt Lake, Kolkata 700098 (India); Raghavendra Reddy, V.; Gupta, Ajay [UGC-DAE Consortium for Scientific Research, University Campus, Khandawa Road, Indore (India)

2011-12-15

We have studied the valence behavior of rare-earth ions, in particular Eu-ions, in a cubic intermetallic compound Ce{sub 0.5}Eu{sub 0.5}Pd{sub 3}B{sub 0.5} which is a homogeneous solid solution of two mixed-valent compounds CePd{sub 3} and EuPd{sub 3}B. Results of {sup 151}Eu Moessbauer spectroscopic measurements show that two different valence states, i.e., divalent- and trivalent-like states of Eu-ions exist in the compound. The possible reason for the observed heterogeneous valency vis-a-vis the variation in the chemical environment and the number of nearest-neighbor B atoms surrounding the Eu-ions has been discussed. Our results demonstrate that B incorporation in such Eu-based cubic intermetallic compounds leads to a situation where heterogeneous-valence state of Eu-ions is an energetically favorable ground state. - Highlights: > Intermetallic compound Ce{sub 0.5}Eu{sub 0.5}Pd{sub 3}B{sub 0.5} crystallizes in a single phase. > Eu-ions in Ce{sub 0.5}Eu{sub 0.5}Pd{sub 3}B{sub 0.5} are charge-ordered compared to +2.3 valency in Ce{sub 0.5}Eu{sub 0.5}Pd{sub 3}. > B incorporation makes charge-ordered state of Eu-ions energetically more favorable. > Nearest-neighbor chemical environment affects the Eu valency.

Thermoelectric properties of p-type pseudo-binary (Ag0.365Sb0.558Te) x -(Bi0.5Sb1.5Te3)1-x (x=0-1.0) alloys prepared by spark plasma sintering

International Nuclear Information System (INIS)

Cui, J.L.; Xue, H.F.; Xiu, W.J.; Jiang, L.; Ying, P.Z.

2006-01-01

In this paper, pseudo-binary (Ag 0.365 Sb 0.558 Te) x -(Bi 0.5 Sb 1.5 Te 3 ) 1- x (x=0-1.0) alloys were prepared using spark plasma sintering technique, and the composition-dependent thermoelectric properties were evaluated. Electrical conductivities range from 7.9x10 4 to 15.6x10 4 Ω -1 m -1 at temperatures of 507 and 318 K, respectively, being about 3.0 and 8.5 times those of Bi 0.5 Sb 1.5 Te 3 alloy at the corresponding temperatures. The optimal dimensionless figure of merit (ZT) of the sample with molar fraction x=0.025 reaches 1.1 at 478 K, whereas that of the ternary Bi 0.5 Sb 1.5 Te 3 alloy is 0.58 near room temperature. The results also reveal that a direct introduction of Ag 0.365 Sb 0.558 Te in the Bi-Sb-Te system is much more effective to the property improvement than naturally precipitated Ag 0.365 Sb 0.558 Te in the Ag-doped Ag-Bi-Sb-Te system. - Graphical abstract: The temperature dependence of the dimensionless thermoelectric figure of merit ZT for different (Ag 0.365 Sb 0.558 Te) x -(Bi 0.5 Sb 1.5 Te 3 ) 1- x (x=0-1.0) alloys prepared by spark plasma sintering

Annealing-induced near-surface ordering in disordered Ga0.5In0.5P

International Nuclear Information System (INIS)

Luo, J.S.; Olson, J.M.; Wu, M.

1995-01-01

Most samples of Ga 0.5 In 0.5 P grown by metalorganic chemical vapor deposition (MOCVD) on (001)-like surfaces are partially ordered and exhibit distinctive reflectance difference spectral (RDS) features associated with the anisotropic properties of the ordered bulk structure. It is known that the ordering is not a ground-state property of the bulk but is surface-induced during growth. On the other hand, Ga 0.5 In 0.5 P grown by liquid-phase epitaxy (LPE) is completely disordered, and it has been shown that its RD spectrum is essentially featureless. In this article, we present a study of the effects of annealing (in a PH 3 /H 2 atmosphere) on LPE-grown Ga 0.5 In 0.5 P using ex situ and in situ RDS. The annealing temperatures and times used in this study (650 degree C and tens of minutes) have virtually no effect on the bulk optical or structural properties of MOCVD-grown Ga 0.5 In 0.5 P. For LPE-grown Ga 0.5 In 0.5 P, we find that annealing induces bulk-like RDS features at both E 0 and E 1 with line shapes similar to those observed for MOCVD-grown ordered Ga 0.5 In 0.5 P. These bulk-like spectral features are, however, due to near-surface reconstruction of Ga and In because they are effectively quenched by exposure to air. Also, the E 0 feature becomes sharper and both the E 0 and the E 1 features red-shift as the annealing process is prolonged. This indicates that this reconstruction is kinetically limited, presumably by the slow interdiffusion of Ga and In necessary to achieve the ordered bulk-like structure. copyright 1995 American Vacuum SocietyGa 0.5 In 0.5 P

Schistosoma mansoni INFECTIONS AMONGST SCHOOL ...

African Journals Online (AJOL)

Administrator

5.00%) of 140 examined at the secondary school category were infected. There were more infections among the secondary school students than their primary school counterparts, though the difference was not significant (p>0.05). Full Length R.

(The evolution of) post-secondary education: a computational model and experiments

Czech Academy of Sciences Publication Activity Database

Ortmann, Andreas; Slobodyan, Sergey

-, č. 355 (2008), s. 1-46 ISSN 1211-3298 R&D Projects: GA MŠk LC542 Institutional research plan: CEZ:MSM0021620846 Keywords : post-secondary education * for-profit higher education providers * computational simulations Subject RIV: AH - Economics http://www.cerge-ei.cz/pdf/wp/Wp355.pdf

Formation of secondary organic aerosol coating on black carbon particles near vehicular emissions

Science.gov (United States)

Lee, Alex K. Y.; Chen, Chia-Li; Liu, Jun; Price, Derek J.; Betha, Raghu; Russell, Lynn M.; Zhang, Xiaolu; Cappa, Christopher D.

2017-12-01

Black carbon (BC) emitted from incomplete combustion can result in significant impacts on air quality and climate. Understanding the mixing state of ambient BC and the chemical characteristics of its associated coatings is particularly important to evaluate BC fate and environmental impacts. In this study, we investigate the formation of organic coatings on BC particles in an urban environment (Fontana, California) under hot and dry conditions using a soot-particle aerosol mass spectrometer (SP-AMS). The SP-AMS was operated in a configuration that can exclusively detect refractory BC (rBC) particles and their coatings. Using the -log(NOx / NOy) ratio as a proxy for photochemical age of air masses, substantial formation of secondary organic aerosol (SOA) coatings on rBC particles was observed due to active photochemistry in the afternoon, whereas primary organic aerosol (POA) components were strongly associated with rBC from fresh vehicular emissions in the morning rush hours. There is also evidence that cooking-related organic aerosols were externally mixed from rBC. Positive matrix factorization and elemental analysis illustrate that most of the observed SOA coatings were freshly formed, providing an opportunity to examine SOA coating formation on rBCs near vehicular emissions. Approximately 7-20 wt % of secondary organic and inorganic species were estimated to be internally mixed with rBC on average, implying that rBC is unlikely the major condensation sink of SOA in this study. Comparison of our results to a co-located standard high-resolution time-of-flight aerosol mass spectrometer (HR-ToF-AMS) measurement suggests that at least a portion of SOA materials condensed on rBC surfaces were chemically different from oxygenated organic aerosol (OOA) particles that were externally mixed with rBC, although they could both be generated from local photochemistry.

[Secondary hypertension].

Science.gov (United States)

Yoshida, Yuichi; Shibata, Hirotaka

2015-11-01

Hypertension is a common disease and a crucial predisposing factor of cardiovascular diseases. Approximately 10% of hypertensive patients are secondary hypertension, a pathogenetic factor of which can be identified. Secondary hypertension consists of endocrine, renal, and other diseases. Primary aldosteronism, Cushing's syndrome, pheochromocytoma, hyperthyroidism, and hypothyroidism result in endocrine hypertension. Renal parenchymal hypertension and renovascular hypertension result in renal hypertension. Other diseases such as obstructive sleep apnea syndrome are also very prevalent in secondary hypertension. It is very crucial to find and treat secondary hypertension at earlier stages since most secondary hypertension is curable or can be dramatically improved by specific treatment. One should keep in mind that screening of secondary hypertension should be done at least once in a daily clinical practice.

Structural characterization of layered Na0.5Co0.5Mn0.5O2 material as a promising cathode for sodium-ion batteries

Science.gov (United States)

Manikandan, Palanisamy; Heo, Seongwoo; Kim, Hyun Woo; Jeong, Hu Young; Lee, Eungje; Kim, Youngsik

2017-09-01

Layered Na0.5Co0.5Mn0.5O2 material is synthesized through a facile mixed hydroxy-carbonate route using (Co0.5Mn0.5)2(OH)2CO3 precursor and well characterized as a hexagonal layered structure under P63/mmc space group. The lattice parameters and unit cell volume (a = 2.8363 Å, c = 11.3152 Å and V = 78.83 Å3) are calculated by Rietveld refinement analysis. A flaky-bundle morphology is obtained to the layered Na0.5Co0.5Mn0.5O2 material with the hexagonal flake size ∼30 nm. Advanced transmission electron microscopic images are revealed the local structure of the layered Na0.5Co0.5Mn0.5O2 material with contrasting bright dots and faint dark dots corresponding to the Co/Mn and Na atoms. Two oxidation and reduction peaks are occurred in a cyclic voltammetric analysis corresponding to Co3+/Co4+ and Mn3+/Mn4+ redox processes. These reversible processes are attributed to the intercalation/de-intercalation of Na+ ions into the host structure of layered Na0.5Co0.5Mn0.5O2 material. Accordingly, the sodium cell is delivered the initial charge-discharge capacity 53/144 mAh g-1 at 0.5 C, which cycling studies are extended to rate capability test at 1 C, 3 C and 5C. Eventually, the Na-ion full-cell is yielded cathode charge-discharge capacity 55/52 mAh g-1 at 0.212 mA and exhibited as a high voltage cathode for Na-ion batteries.

Psychologic and sexual dysfunction in primary and secondary infertile male patients

Directory of Open Access Journals (Sweden)

Aytac Sahin

2017-06-01

Full Text Available Objective: The aim of this study was to compare depression and sexual dysfunctions observed in primary and secondary infertile patients. Material and method: The study was performed in 39 primary and 31 secondary infertile male patients. Male sexual health was evaluated using the International Index of Erectile Function (IIEF score and depression with Beck Depression Inventory (BDI. Results: Mean age of the participants and their partners were 31.54 ± 5.37 (range, 24-48 yrs, and 28.16 ± 5.58 (range, 20- 46 yrs years, respectively. Mean duration of their marriage ranged between 1 and 17 years (mean, 5.06 ± 4.15 yrs. A statistically significant intergroup difference was detected between groups as for BDI scores (p = 0.015; p < 0. 05. BDI scores of the primary group were significantly lower than those of the secondary group. A statistically and extremely significant difference was detected between IIEF scores of the groups (p = 0.006; p < 0.01. IIEF scores of the primary infertile group were higher than those of the secondary group. Conclusion: Our study, frequency of the depression and erectile dysfunction seen in the patients with secondary infertility was seen significantly higher than the patients with primary infertility.

Secondary pigmentary glaucoma in patients with underlying primary pigment dispersion syndrome

Directory of Open Access Journals (Sweden)

Sivaraman KR

2013-03-01

Full Text Available Kavitha R Sivaraman, Chirag G Patel, Thasarat S Vajaranant, Ahmad A ArefDepartment of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago School of Medicine, Chicago, IL, USAAbstract: Primary pigment dispersion syndrome (PPDS is a bilateral condition that occurs in anatomically predisposed individuals. PPDS may evolve into pigmentary glaucoma, but it is difficult to predict which patients will progress. Secondary pigment dispersion is more often unilateral and acquired as a result of surgery, trauma, or intraocular tumor, but can likewise lead to pigmentary glaucoma. We report two cases of patients with bilateral PPDS who developed secondary pigment dispersion and pigmentary glaucoma in one eye. Patients with PPDS who acquire a secondary mechanism of pigment dispersion may be at an increased risk of progression to pigmentary glaucoma, presumably due to an increased burden of liberated pigment. In addition to regular surveillance for progression to glaucoma from PPDS, secondary causes of pigmentary dispersion in these eyes should be considered when patients present with grossly asymmetric findings. When secondary pigment dispersion is identified in eyes with PPDS, we recommend prompt intervention to alleviate the cause of secondary pigment dispersion and/or aggressive control of intraocular pressure to limit glaucomatous damage.Keywords: primary pigment dispersion syndrome, pigmentary glaucoma

RuO4-mediated oxidation of secondary amines 2. imines as main reaction intermediates

Directory of Open Access Journals (Sweden)

Florea Cristina A.

2017-01-01

Full Text Available Oxidation by RuO4 (generated in situ from RuO2 and NaIO4 of secondary amines such as Bn–NH–CH2R (1; R=H, Me gave complex reaction mixtures, but mainly amides. In the presence of cyanide, the leading products were α-aminonitriles. Comparison of the oxidation products of 1 with those from the corresponding imines PhCH=N–CH2R and Bn–N=CH–R showed that formation of the indicated imines is the first main step in the oxidation of 1. A detailed mechanism is proposed.

Ethylbenzene dehydrogenation over Mg3Fe0.5−xCoxAl0.5 catalysts derived from hydrotalcites: Comparison with Mg3Fe0.5−yNiyAl0.5 catalysts

KAUST Repository

Atanda, Luqman A.; Balasamy, Rabindran J.; Khurshid, Alam; Al-Ali, Ali A S; Sagata, Kunimasa; Asamoto, Makiko; Yahiro, Hidenori; Nomura, Kiyoshi; Sano, Tsuneji; Takehira, Katsuomi; Al-Khattaf, Sulaiman S.

2011-01-01

A series of Mg3Fe0.5-xCoxAl0.5 (x = 0-0.5) catalysts were prepared from hydrotalcite precursors and their activities in the dehydrogenation of ethylbenzene were compared with those of a series of Mg3Fe0.5-yNiyAl0.5 (y = 0-0.5) catalysts also derived

NCBI nr-aa BLAST: CBRC-TGUT-05-0034 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-TGUT-05-0034 ref|NP_000854.1| 5-hydroxytryptamine (serotonin) receptor 1B [Hom...o sapiens] ref|NP_001009102.1| 5-hydroxytryptamine (serotonin) receptor 1B [Pan troglodytes] sp|P28222|5HT1B...HT-1B) (Serotonin receptor 1B) (5-HT1B) gb|AAA58675.1| serotonin 1Db receptor gb|AAA36029.1| serotonin recep...tor gb|AAA36030.1| 5-hyroxytryptamine 1D receptor dbj|BAA01763.1| serotonin 1B receptor [Homo sapiens] gb|AAA60316.1| serotonin... 1D receptor emb|CAB51537.1| 5-hydroxytryptamine (serotonin) r

Structural Evolution of the R-T Phase Boundary in KNN-Based Ceramics

KAUST Repository

Lv, Xiang; Wu, Jiagang; Xiao, Dingquan; Zhu, Jianguo; Zhang, Xixiang

2017-01-01

, the structural evolution of R-T phase boundary from -150 °C to 200 °C is investigated in (0.99-x)K0.5Na0.5Nb1-ySbyO3-0.01CaSnO3-xBi0.5K0.5HfO3 (where x=0~0.05 with y=0.035, and y=0~0.07 with x=0.03) ceramics. Through temperature-dependent powder X-ray diffraction

At R802

CERN Multimedia

1974-01-01

The photo shows the magnet (blue) of the spectrometer covering nearly the complete solid angle used by the CERN-Rome Collaboration to study negative particles at angles close to 0 deg with respect to one of the two colliding beams (Annual Report 1974, p. 108 and Photo Archive 7402246). Particles were identified by four threshold Cerenkov counters (on the left, bottom) and their trajectories were determined by twelve planes of MWPC (multiwire proportional chambers). The angular correlations between these particles and the over-all distribution of charged secondaries as observed in the hodoscope of R801 were also determined. On the centre a surveyor.

Biomass resilience of Neotropical secondary forests.

Science.gov (United States)

Poorter, Lourens; Bongers, Frans; Aide, T Mitchell; Almeyda Zambrano, Angélica M; Balvanera, Patricia; Becknell, Justin M; Boukili, Vanessa; Brancalion, Pedro H S; Broadbent, Eben N; Chazdon, Robin L; Craven, Dylan; de Almeida-Cortez, Jarcilene S; Cabral, George A L; de Jong, Ben H J; Denslow, Julie S; Dent, Daisy H; DeWalt, Saara J; Dupuy, Juan M; Durán, Sandra M; Espírito-Santo, Mario M; Fandino, María C; César, Ricardo G; Hall, Jefferson S; Hernandez-Stefanoni, José Luis; Jakovac, Catarina C; Junqueira, André B; Kennard, Deborah; Letcher, Susan G; Licona, Juan-Carlos; Lohbeck, Madelon; Marín-Spiotta, Erika; Martínez-Ramos, Miguel; Massoca, Paulo; Meave, Jorge A; Mesquita, Rita; Mora, Francisco; Muñoz, Rodrigo; Muscarella, Robert; Nunes, Yule R F; Ochoa-Gaona, Susana; de Oliveira, Alexandre A; Orihuela-Belmonte, Edith; Peña-Claros, Marielos; Pérez-García, Eduardo A; Piotto, Daniel; Powers, Jennifer S; Rodríguez-Velázquez, Jorge; Romero-Pérez, I Eunice; Ruíz, Jorge; Saldarriaga, Juan G; Sanchez-Azofeifa, Arturo; Schwartz, Naomi B; Steininger, Marc K; Swenson, Nathan G; Toledo, Marisol; Uriarte, Maria; van Breugel, Michiel; van der Wal, Hans; Veloso, Maria D M; Vester, Hans F M; Vicentini, Alberto; Vieira, Ima C G; Bentos, Tony Vizcarra; Williamson, G Bruce; Rozendaal, Danaë M A

2016-02-11

Land-use change occurs nowhere more rapidly than in the tropics, where the imbalance between deforestation and forest regrowth has large consequences for the global carbon cycle. However, considerable uncertainty remains about the rate of biomass recovery in secondary forests, and how these rates are influenced by climate, landscape, and prior land use. Here we analyse aboveground biomass recovery during secondary succession in 45 forest sites and about 1,500 forest plots covering the major environmental gradients in the Neotropics. The studied secondary forests are highly productive and resilient. Aboveground biomass recovery after 20 years was on average 122 megagrams per hectare (Mg ha(-1)), corresponding to a net carbon uptake of 3.05 Mg C ha(-1) yr(-1), 11 times the uptake rate of old-growth forests. Aboveground biomass stocks took a median time of 66 years to recover to 90% of old-growth values. Aboveground biomass recovery after 20 years varied 11.3-fold (from 20 to 225 Mg ha(-1)) across sites, and this recovery increased with water availability (higher local rainfall and lower climatic water deficit). We present a biomass recovery map of Latin America, which illustrates geographical and climatic variation in carbon sequestration potential during forest regrowth. The map will support policies to minimize forest loss in areas where biomass resilience is naturally low (such as seasonally dry forest regions) and promote forest regeneration and restoration in humid tropical lowland areas with high biomass resilience.

Selective Etching of Silicon in Preference to Germanium and Si0.5Ge0.5.

Science.gov (United States)

Ahles, Christopher F; Choi, Jong Youn; Wolf, Steven; Kummel, Andrew C

2017-06-21

The selective etching characteristics of silicon, germanium, and Si 0.5 Ge 0.5 subjected to a downstream H 2 /CF 4 /Ar plasma have been studied using a pair of in situ quartz crystal microbalances (QCMs) and X-ray photoelectron spectroscopy (XPS). At 50 °C and 760 mTorr, Si can be etched in preference to Ge and Si 0.5 Ge 0.5 , with an essentially infinite Si/Ge etch-rate ratio (ERR), whereas for Si/Si 0.5 Ge 0.5 , the ERR is infinite at 22 °C and 760 mTorr. XPS data showed that the selectivity is due to the differential suppression of etching by a ∼2 ML thick C x H y F z layer formed by the H 2 /CF 4 /Ar plasma on Si, Ge, and Si 0.5 Ge 0.5 . The data are consistent with the less exothermic reaction of fluorine radicals with Ge or Si 0.5 Ge 0.5 being strongly suppressed by the C x H y F z layer, whereas, on Si, the C x H y F z layer is not sufficient to completely suppress etching. Replacing H 2 with D 2 in the feed gas resulted in an inverse kinetic isotope effect (IKIE) where the Si and Si 0.5 Ge 0.5 etch rates were increased by ∼30 times with retention of significant etch selectivity. The use of D 2 /CF 4 /Ar instead of H 2 /CF 4 /Ar resulted in less total carbon deposition on Si and Si 0.5 Ge 0.5 and gave less Ge enrichment of Si 0.5 Ge 0.5 . These results are consistent with the selectivity being due to the differential suppression of etching by an angstrom-scale carbon layer.

Antecedents of primary and secondary acute social withdrawal

Directory of Open Access Journals (Sweden)

Iryna Frankova

2017-11-01

Full Text Available Background. The phenomenon of acute social withdrawal (ASW is becoming more common and widespread nowadays and can be characterized by complete solitude/alienation from society for 6 months or longer. Previous studies of the ASW included patients with mental disorders and were focused on the psychopathological features of secondary ASW caused by depression, social phobia, or bulimia. Aim. To increase the effectiveness of acute social withdrawal differential diagnostics by determining the etiopathogenetic factors of its development and psychopathological features to improve further management of this condition. Materials and methods. At the Department of Psychosomatic Medicine and Psychotherapy of Bogomolets National Medical University 70 patients with ASW were examined: the first experimental group (EG1 - patients with mental disorders and ASW (n = 42, and the second (EG2 - a mentally healthy contingent with primary ASW (n = 28. Healthy people without ASW (n=56, control group, CG as well were examined. The following methods were used: Buss Durkee Hostility Inventory, Victim Behavior Questionnaire, Toronto Alexithymia Scale (TAS-26, Leongard-Schmishek Accentuated Personality Trait Questionnaire, Life Event Questionnaire (LEQ, Chaban Quality of Life Scale. Results. Comparing EG and CG regarding significance, there were determined several differences. The level of alexithymia in the EG was significantly higher than in the CG (p<0.005. The quality of life in the EG was significantly lower than in the CG (p<0.005.  According to the Leongard-Schmishek test in EG accentuated personality traits such cyclothymia, hyperthymia, dysthymia, anxiety (p<0.005, pedantic (p<0.05, demonstrativeness (p <0.1 were significantly higher than in the CG. According to the Buss-Durkee Hostility Inventory, such indicators as resentment (p<0.005, irritability (p<0.05, suspicion (p<0.05 and, as a consequence, an index of aggression (IA, (p<0.05 were significantly higher

(The evolution of) post-secondary education: a computational model and experiments

Czech Academy of Sciences Publication Activity Database

Ortmann, Andreas; Slobodyan, Sergey

-, č. 355 (2008), s. 1-46 ISSN 1211-3298 R&D Projects: GA MŠk LC542 Institutional research plan: CEZ:AV0Z70850503 Keywords : post-secondary education * for-profit higher education providers * computational simulations Subject RIV: AH - Economics http://www.cerge-ei.cz/pdf/wp/Wp355.pdf

Magnetic and magnetocaloric properties of the alloys Mn2-xFexP0.5As0.5 (0⩽x⩽0.5)

Science.gov (United States)

Gribanov, I. F.; Golovchan, A. V.; Varyukhin, D. V.; Val'kov, V. I.; Kamenev, V. I.; Sivachenko, A. P.; Sidorov, S. L.; Mityuk, V. I.

2009-10-01

The results of investigations of the magnetic and magnetocaloric properties of alloys from the system Mn2-xFexP0.5As0.5 (0⩽x⩽0.5) are presented. The magnetization measurements are performed in the temperature interval 4.2-700K in magnetic fields up to 8T. The entropy changes ΔS with the magnetic field changing from 0 to 2, 4, 5, and 8T are determined from the magnetization isotherms obtained near temperatures of the spontaneous appearance of the ferromagnetic state (TC,TAF -FM1), and the curves ΔS(T0) are constructed. It is found that TC and TAF-FM1 decrease monotonically with increasing manganese concentration and that the ferromagnetic phase is completely suppressed in Mn1.5Fe0.5P0.5As0.5. It is found that the concentration dependences of the maximum entropy jump (and the corresponding cold-storage capacity) and the magnitudes of the ferromagnetic moment of the unit cell with maxima for x =0.9 and 0.8 show extremal behavior. The data obtained are compared with the ferromagnetic moments calculated from first principles by the Korringa-Kohn-Rostoker method using the coherent-potential approximation (KKR-CPA)—the discrepancy for 0.5⩽x⩽0.7 is attributed to the appearance of an antiferromagnetic component of the magnetic structure. It is concluded that the alloys Mn2-xFexP0.5As0.5 have promise for use in magnetic refrigerators operating at room temperature.

Characteristics and generation of secondary jets and secondary gigantic jets

Science.gov (United States)

Lee, Li-Jou; Huang, Sung-Ming; Chou, Jung-Kung; Kuo, Cheng-Ling; Chen, Alfred B.; Su, Han-Tzong; Hsu, Rue-Rou; Frey, Harald U.; Takahashi, Yukihiro; Lee, Lou-Chuang

2012-06-01

Secondary transient luminous events (TLEs) recorded by the ISUAL-FORMOSAT2 mission can either be secondary jets or secondary gigantic jets (GJs), depending on their terminal altitudes. The secondary jets emerge from the cloud top beneath the preceding sprites and extend upward to the base of the sprites at ˜50 km. The secondary jets likely are negative electric discharges with vertically straight luminous columns, morphologically resembling the trailing jet of the type-I GJs. The number of luminous columns in a secondary jet seems to be affected by the size of the effective capacitor plate formed near the base of the preceding sprites and the charge distribution left behind by the sprite-inducing positive cloud-to-ground discharges. The secondary GJs originate from the cloud top under the shielding area of the preceding sprites, and develop upward to reach the lower ionosphere at ˜90 km. The observed morphology of the secondary GJs can either be the curvy shifted secondary GJs extending outside the region occupied by the preceding sprites or the straight pop-through secondary GJs developing through the center of the preceding circular sprites. A key factor in determining the terminal height of the secondary TLEs appears to be the local ionosphere boundary height that established by the preceding sprites. The abundance and the distribution of the negative charge in the thundercloud following the sprite-inducing positive cloud-to-ground discharges may play important role in the generation of the secondary TLEs.

REOSC Delivers the Best Astronomical Mirror in the World to ESO

Science.gov (United States)

1999-12-01

On December 14, 1999, REOSC , the Optical Department of the SAGEM Group , finished the polishing of the fourth 8.2-m main mirror for the Very Large Telescope (VLT) of the European Southern Observatory. The mirror was today delivered to ESO at a ceremony at the REOSC factory in Saint Pierre du Perray, just south of Paris. The precision of the form of the mirror that was achieved during the polishing process is 8.5 nanometer (1 nanometer = 1 millionth of a millimetre) over the optical surface. This exceptional value corresponds to an optical resolution (theoretical image sharpness) of 0.03 arcseconds in the visible spectrum. This corresponds to distinguishing two objects separated by only 15 cm at a distance of 1000 km and will allow to detect astronomical objects that are 10,000 million times fainter than what can be perceived with the unaided eye. This impressive measure of quality, achieved by the REOSC teams during much painstaking work, implies that this VLT mirror is the most accurate in the world. In fact, all four 8.2-m VLT main mirrors polished by REOSC are well within the very strict specifications set by ESO, but this is the best of them all. The celebration today is the successful highlight of a contract initiated more than ten years ago, during which REOSC has perfected new polishing and control techniques - innovations improved and developed in a unique workshop dedicated to these giant mirrors. These methods and means are directly applicable to the new generations of segmented mirrors that are now being developed for astronomy and space observations. They are, in this sense, at the foremost front of optical technology. REOSC, the Optical Department of the SAGEM Group , is specialised in the study and realisation of high-precision optics for astronomy, space, defence, science and industry. For earlier information about the work on the VLT mirrors, cf. ESO Press Release 15/95 (13 November 1995). The SAGEM Group is a French high-technology group. It

Secondary Forest Age and Tropical Forest Biomass Estimation Using TM

Science.gov (United States)

Nelson, R. F.; Kimes, D. S.; Salas, W. A.; Routhier, M.

1999-01-01

The age of secondary forests in the Amazon will become more critical with respect to the estimation of biomass and carbon budgets as tropical forest conversion continues. Multitemporal Thematic Mapper data were used to develop land cover histories for a 33,000 Square kM area near Ariquemes, Rondonia over a 7 year period from 1989-1995. The age of the secondary forest, a surrogate for the amount of biomass (or carbon) stored above-ground, was found to be unimportant in terms of biomass budget error rates in a forested TM scene which had undergone a 20% conversion to nonforest/agricultural cover types. In such a situation, the 80% of the scene still covered by primary forest accounted for over 98% of the scene biomass. The difference between secondary forest biomass estimates developed with and without age information were inconsequential relative to the estimate of biomass for the entire scene. However, in futuristic scenarios where all of the primary forest has been converted to agriculture and secondary forest (55% and 42% respectively), the ability to age secondary forest becomes critical. Depending on biomass accumulation rate assumptions, scene biomass budget errors on the order of -10% to +30% are likely if the age of the secondary forests are not taken into account. Single-date TM imagery cannot be used to accurately age secondary forests into single-year classes. A neural network utilizing TM band 2 and three TM spectral-texture measures (bands 3 and 5) predicted secondary forest age over a range of 0-7 years with an RMSE of 1.59 years and an R(Squared) (sub actual vs predicted) = 0.37. A proposal is made, based on a literature review, to use satellite imagery to identify general secondary forest age groups which, within group, exhibit relatively constant biomass accumulation rates.

Effects of air melting on Fe/0.3/3Cr/0.5Mo/2Mn and Fe/0.3C/3Cr/0.5Mo/2Ni structural alloy steels

International Nuclear Information System (INIS)

Steinberg, B.

1979-06-01

Changing production methods of a steel from vacuum melting to air melting can cause an increase in secondary particles, such as oxides and nitrides, which may have detrimental effects on the mechanical properties and microstructure of the alloy. In the present study a base alloy of Fe/0.3C/3Cr/0.5Mo with either 2Mn or 2Ni added was produced by air melting and its mechanical properties and microstructure were compared to an identical vacuum melted steel. Significant differences in mechanical behavior, morphology, and volume fraction of undissolved inclusions have been observed as a function of composition following air melting. For the alloy containing manganese, all properties remained very close to vacuum melted values but the 2Ni alloy displayed a marked loss in Charpy impact toughness and plane strain fracture toughness. This loss is attributed to an increase in volume fraction of secondary particles in the nickel alloy, as opposed to both the Mn alloy and vacuum melted alloys, as well as to substaintially increased incidence of linear coalescence of voids. Microstructural features are discussed

miR-21 may acts as an oncomir by targeting RECK, a matrix metalloproteinase regulator, in prostate cancer

Directory of Open Access Journals (Sweden)

Reis Sabrina

2012-05-01

Full Text Available Abstract Background Prognosis of prostate cancer (PCa is based mainly in histological aspects together with PSA serum levels that not always reflect the real aggressive potential of the neoplasia. The micro RNA (miRNA mir-21 has been shown to regulate invasiveness in cancer through translational repression of the Metaloproteinase (MMP inhibitor RECK. Our aim is to investigate the levels of expression of RECK and miR-21 in PCa comparing with classical prognostic factors and disease outcome and also test if RECK is a target of miR-21 in in vitro study using PCa cell line. Materials and methods To determine if RECK is a target of miR-21 in prostate cancer we performed an in vitro assay with PCa cell line DU-145 transfected with pre-miR-21 and anti-miR-21. To determine miR-21 and RECK expression levels in PCa samples we performed quantitative real-time polymerase chain reaction (qRT-PCR. Results The in vitro assays showed a decrease in expression levels of RECK after transfection with pre-miR-21, and an increase of MMP9 that is regulated by RECK compared to PCa cells treated with anti-miR-21. We defined three profiles to compare the prognostic factors. The first was characterized by miR-21 and RECK underexpression (N = 25 the second was characterized by miR-21 overexpression and RECK underexpression (N = 12, and the third was characterized by miR-21 underexpression and RECK overexpression (N = 16. From men who presented the second profile (miR-21 overexpression and RECK underexpression 91.7% were staged pT3. For the other two groups 48.0%, and 46.7% of patients were staged pT3 (p = 0.025. Conclusions Our results demonstrate RECK as a target of miR-21. We believe that miR-21 may be important in PCa progression through its regulation of RECK, a known regulator of tumor cell invasion.

The validity of the Addenbrooke's Cognitive Examination-Revised (ACE-R) in acute stroke.

Science.gov (United States)

Morris, Katie; Hacker, Vicki; Lincoln, Nadina Berrice

2012-01-01

The purpose was to examine the validity of the Addenbrooke's Cognitive Examination Revised (ACE-R) as a screening measure to detect cognitive impairment after stroke. Stroke patients in hospital were recruited and the ACE-R, which includes the Mini-Mental Status Examination (MMSE), was administered, followed by a battery of neuropsychological tests, which served as the 'gold standard' for classification of cognitive impairment. The diagnostic validity of the ACE-R was determined by ROC analysis. Of the 101 patients who completed the ACE-R, 61 also completed the neuropsychological assessment. Both the MMSE and the ACE-R were found to have inadequate diagnostic validity for the detection of overall cognitive impairment (MMSE AUC = 0.53, p > 0.05; ACE-R AUC = 0.53, p > 0.05). The ACE-R subscales predicted impairment in specific cognitive domains significantly better than chance; Visuospatial (AUC = 0.71, p cognitive functioning. The ACE-R was not a suitable measure to screen for overall cognitive impairment in acute stroke patients, but was able to detect impairment in visuospatial, attention and executive domains.

Secondary electron emission with molecular projectiles

International Nuclear Information System (INIS)

Kroneberger, K.; Rothard, H.; Koschar, P.; Lorenzen, P.; Kemmler, J.; Keller, N.; Maier, R.; Groeneveld, K.O.; Clouvas, A.; Veje, E.

1990-01-01

The authors present results for the secondary electron emission (SEE) from thin foil targets, induced by both molecular ions and their atomic constituents as projectiles. The Sternglass theory for kinetic SEE states a proportionality between γ and the electronic stopping power, S e , which has been verified in various experiments. With comparing secondary electron (SE) yields induced by molecular projectiles to those induced by monoatomic projectiles, it is therefore possible to test models for the energy loss of molecular or cluster projectiles. Since the atomic constituents of the molecule are repelled from each other due to Coulomb explosion (superimposed by multiple scattering) while traversing the solid, it is interesting to measure the residual mutual influence on SEE and S e with increasing internuclear separation. This can only be achieved with thin foils, where (as in the present case) the SE-yields from the exit surface can be measured separately. The authors measured the SE-yields from the entrance (γ B ) and exit (γ F ) surfaces of thin C- and Al-foils (150 to 1,000 angstrom) with CO + , C + and O + (15 to 85 keV/u) and H 2 + and H + (0.3 to 1.2 MeV/u). The molecular effect defined as the ratio R(γ) between the yields induced by molecular projectiles and the sum of those induced by their atomic constituents was calculated. The energy dependence of R(γ) can be well represented by the calculated energy loss ratio of di-proton-clusters by Brandt. This supports Brandt's model for the energy loss of clusters

Novel evolutionary lineages revealed in the Chaetothyriales (Fungi) based on multigene phylogenetic analyses and comparison of ITS secondary structure

Czech Academy of Sciences Publication Activity Database

Réblová, Martina; Untereiner, W. A.; Réblová, K.

2013-01-01

Roč. 8, č. 5 (2013), e63547 E-ISSN 1932-6203 R&D Projects: GA ČR GAP506/12/0038 Institutional support: RVO:67985939 Keywords : Cyphelophora * Phialophora * secondary structure Subject RIV: EF - Botanics Impact factor: 3.534, year: 2013

Geomagnetic activity at Northern Hemisphere's mid-latitude ground stations: How much can be explained using TS05 model

Science.gov (United States)

Castillo, Yvelice; Pais, Maria Alexandra; Fernandes, João; Ribeiro, Paulo; Morozova, Anna L.; Pinheiro, Fernando J. G.

2017-12-01

For the 2007 to 2014 period, we use a statistical approach to evaluate the performance of Tsyganenko and Sitnov [2005] semi-empirical model (TS05) in estimating the magnetospheric transient signal observed at four Northern Hemisphere mid-latitude ground stations: Coimbra, Portugal; Panagyurishte, Bulgary; Novosibirsk, Russia and Boulder, USA. Using hourly mean data, we find that the TS05 performance is clearly better for the X (North-South) than for the Y (East-West) field components and for more geomagnetically active days as determined by local K-indices. In ∼ 50% (X) and ∼ 30% (Y) of the total number of geomagnetically active days, correlation values yield r ≥ 0.7. During more quiet conditions, only ∼ 30% (X) and ∼ 15% (Y) of the number of analyzed days yield r ≥ 0.7. We compute separate contributions from different magnetospheric currents to data time variability and to signal magnitude. During more active days, all tail, symmetric ring and partial ring currents contribute to the time variability of X while the partial ring and field aligned currents contribute most to the time variability of Y. The tail and symmetric ring currents are main contributors to the magnitude of X. In the best case estimations when r ≥ 0.7, remaining differences between observations and TS05 predictions could be explained by global induction in the Earth's upper layers and crustal magnetization. The closing of field aligned currents through the Earth's center in the TS05 model seems to be mainly affecting the Y magnetospheric field predictions.

RuO4-mediated oxidation of secondary amines: Part 1. Are hydroxylamines main intermediates?

Directory of Open Access Journals (Sweden)

Florea Cristina A.

2016-01-01

Full Text Available The RuO4-catalyzed oxidation of secondary amines Bn-NH-CH2R (1a-b; R=H, Me gave mainly amides, but minute amounts of nitrones PhCH=N(O-CH2R (9a-b and traces of Bn-N(OH-CH2R (R=H, 4a were also detected. In the presence of cyanide, up to 22 reaction products were identified, but mainly α-aminonitriles. Comparison of the oxidation products of 1a-b with those of 4a-b, 9a-b, and Bn-N(O=CHR (10a-b showed that 4a-b cannot be main reaction intermediates formed from 1a-b.

Connecting practice-based research and school development. Cross-professional collaboration in secondary education

NARCIS (Netherlands)

Schenke, W.

2015-01-01

Research and development (R&D) projects can increasingly be observed in secondary schools in the Netherlands. In such projects, cross-professional collaboration of school leaders and teachers with researchers, advisers, and supervisors is encouraged. These professionals have the purpose to stimulate

Substitution behavior of x(Na0.5K0.5)NbO3-(1 − x)BaTiO3 ceramics for multilayer ceramic capacitors by a near edge x-ray absorption fine structure analysis

International Nuclear Information System (INIS)

Ha, Jooyeon; Ryu, Jiseung; Lee, Heesoo

2014-01-01

The doping effect of (Na 0.5 K 0.5 )NbO 3 (NKN) as alternatives for rare-earth elements on the electrical properties of BaTiO 3 has been investigated, in terms of their substitution behavior. The dielectric constant of a specimen with x = 0.05 was about 79% higher than that of pure BaTiO 3 , and the temperature coefficient of capacitance was satisfied by the X7R specification. The specimen with x = 0.05 showed the lowest tetragonality among the four compositions and had a fine grain size of 5+ ion for Ti-sites. Therefore, the simultaneous substitution of Na + /K + and Nb 5+ ions into BaTiO 3 can improve dielectric properties, based on the charge-transfer process.

Tc-99m erythromycin lactobionate inhalation scintigraphy in parenchymal lung diseases

Energy Technology Data Exchange (ETDEWEB)

Durak, Hatice E-mail: hdurak@kordon.deu.edu.tr; Aktogu, Serir; Degirmenci, Berna; Sayit, Elvan; Ertay, Tuerkan; Dereli, Sevket

1999-08-01

We have investigated Technetium 99m erythromycin lactobionate (Tc 99m EL) clearance from the lungs after inhalation, in the presence of an alveolitis. Eighteen patients (6 sarcoidosis, 7 idiopathic fibrosis, and 5 miliary tuberculosis) were imaged after the patients inhaled 1,110 MBq of Tc 99m EL. Clearance half time for the first 45 min, for 24 h, and retention at 24 h correlated with percentage of lymphocytes in bronchoalveolar lavage fluid (BAL) (r=.729, r=.883, and r=.826, respectively). There was a positive correlation between peripheral penetration (PP) and forced expiratory volume in 1 s (FEV{sub 1}) (r=.806) and forced vital capacity (FVC) (r=.781). Retention was more marked in sarcoidosis compared with tuberculosis (0.02505). Radioaerosol lung imaging may reflect the pulmonary function impairment in parenchymal lung diseases. Retention of Tc 99m EL may be related to number of BAL cells or presence of a lymphocytic alveolitis. Long residency time of Tc 99m EL in the lungs implies that erythromycin can also be administered by inhalation for therapeutic purposes.

Substitution behavior of x(Na0.5K0.5)NbO3-(1 - x)BaTiO3 ceramics for multilayer ceramic capacitors by a near edge x-ray absorption fine structure analysis

Science.gov (United States)

Ha, Jooyeon; Ryu, Jiseung; Lee, Heesoo

2014-06-01

The doping effect of (Na0.5K0.5)NbO3 (NKN) as alternatives for rare-earth elements on the electrical properties of BaTiO3 has been investigated, in terms of their substitution behavior. The dielectric constant of a specimen with x = 0.05 was about 79% higher than that of pure BaTiO3, and the temperature coefficient of capacitance was satisfied by the X7R specification. The specimen with x = 0.05 showed the lowest tetragonality among the four compositions and had a fine grain size of x-ray absorption fine structure spectroscopy, the practical substitution behavior was defined by the change in Ti 3d orbital states. The energy separation of the Ti 3d orbitals was more apparent with the specimen of x = 0.05, which is related to the donor level from the donor substitution of Nb5+ ion for Ti-sites. Therefore, the simultaneous substitution of Na+/K+ and Nb5+ ions into BaTiO3 can improve dielectric properties, based on the charge-transfer process.

Salivary leptin and TAS1R2/TAS1R3 polymorphisms are related to sweet taste sensitivity and carbohydrate intake from a buffet meal in healthy young adults.

Science.gov (United States)

Han, Pengfei; Keast, Russell S J; Roura, Eugeni

2017-11-01

The influence of sweet taste sensitivity on food intake is not well understood. We investigated the involvement of salivary leptin and SNP of the sweet taste receptor genes (TAS1R2/TAS1R3) on sweet taste sensitivity, sensory-specific satiety (SSS) and macronutrient intake in healthy human adults. In all, nineteen high sweet sensitivity (HS) and eleven low sweet sensitivity (LS) subjects were classified based on the sweetness perception of one solution (9 mm sucrose) forced-choice triangle test. All participants completed a randomised crossover design experiment where they consumed one of three iso-energetic soup preloads differing in primary taste quality (sweet, non-sweet taste-control or no-taste energy-control). A period of 1 h after the preload, participants were offered a buffet meal consisting of foods varying in taste (sweet or non-sweet) and fat content. Subjective measures included hunger/fullness and SSS for sweetness. Saliva and buccal cells were collected to measure leptin level and to study the TAS1R2/TAS1R3 specific SNP, respectively. Salivary leptin concentrations were significantly higher in LS than HS participants (P<0·05). In addition, HS showed stronger sweet SSS compared with LH participants (P<0·05), and consumed less carbohydrate (% energy) and more non-sweet foods than LS (P<0·01 and P<0·05, respectively). Alleles from each TAS1R2 locus (GG compared with AA alleles of rs12033832, and CT/CC compared with TT alleles of rs35874116) were related to higher consumption of carbohydrates (% energy) and higher amount of sweet foods, respectively (P<0·05). In contrast, no associations were found for the TAS1R3 alleles. These results contribute to understand the links between taste sensitivity, macronutrient appetite and food consumption.

Composition of secondary alcohols, ketones, alkanediols, and ketols in Arabidopsis thaliana cuticular waxes

Science.gov (United States)

Wen, Miao; Jetter, Reinhard

2009-01-01

Arabidopsis wax components containing secondary functional groups were examined (i) to test the biosynthetic relationship between secondary alcohols and ketols and (ii) to determine the regiospecificity and substrate preference of the enzyme involved in ketol biosynthesis. The stem wax of Arabidopsis wild type contained homologous series of C27 to C31 secondary alcohols (2.4 μg cm−2) and C28 to C30 ketones (6.0 μg cm−2) dominated by C29 homologues. In addition, compound classes containing two secondary functional groups were identified as C29 diols (∼0.05 μg cm−2) and ketols (∼0.16 μg cm−2). All four compound classes showed characteristic isomer distributions, with functional groups located between C-14 and C-16. In the mah1 mutant stem wax, diols and ketols could not be detected, while the amounts of secondary alcohols and ketones were drastically reduced. In two MAH1-overexpressing lines, equal amounts of C29 and C31 secondary alcohols were detected. Based on the comparison of homologue and isomer compositions between the different genotypes, it can be concluded that biosynthetic pathways lead from alkanes to secondary alcohols, and via ketones or diols to ketols. It seems plausible that MAH1 is the hydroxylase enzyme involved in all these conversions in Arabidopsis thaliana. PMID:19346242

Predictors for secondary therapy after surgical resection of nonfunctioning pituitary adenomas.

Science.gov (United States)

Ratnasingam, Jeyakantha; Lenders, Nele; Ong, Benjamin; Boros, Samuel; Russell, Anthony W; Inder, Warrick J; Ho, Ken K Y

2017-12-01

Factors determining recurrence of nonfunctioning pituitary adenomas (NFAs) that require further therapy are unclear as are postoperative follow-up imaging guidelines. We aimed to identify predictors for secondary therapy after surgical resection of NFAs and use this knowledge to inform postoperative management. A single-centre retrospective study of surgically resected NFAs in 108 patients followed for up to 15 years. Serial tumour images were analysed for size, location and growth rate (GR) and tissue analysed for hormone cell type and proliferation indices with secondary treatment as outcome measure. Twenty-four of 66 (36%) patients harbouring a postoperative remnant required secondary treatment, all occurring within 10 years. No secondary treatment was required in any of 42 patients with complete tumour resection. Age, gender, remnant volume and tumour histology were not different between patients requiring and not requiring secondary therapy. Remnant GRs in those requiring secondary therapy were more than 10-fold higher (Prisk for secondary therapy. Tumour GR in the first three postoperative years correlated significantly (r 2 =.6, P<.01) with GR during the period of follow-up. In surgically resected NFAs further treatment is dependent on the presence of residual tumour, growth rate and location but not tumour histology. Postoperative growth rate of NFAs in the first 3 years of imaging can be used to tailor long-term follow-up to optimize use of health resources. © 2017 John Wiley & Sons Ltd.

Dielectric properties of (K0.5Na0.5)NbO3-(Bi0.5Li0.5)ZrO3 lead-free ceramics as high-temperature ceramic capacitors

Science.gov (United States)

Yan, Tianxiang; Han, Feifei; Ren, Shaokai; Ma, Xing; Fang, Liang; Liu, Laijun; Kuang, Xiaojun; Elouadi, Brahim

2018-04-01

(1 - x)K0.5Na0.5NbO3- x(Bi0.5Li0.5)ZrO3 (labeled as (1 - x)KNN- xBLZ) lead-free ceramics were fabricated by a solid-state reaction method. A research was conducted on the effects of BLZ content on structure, dielectric properties and relaxation behavior of KNN ceramics. By combining the X-ray diffraction patterns with the temperature dependence of dielectric properties, an orthorhombic-tetragonal phase coexistence was identified for x = 0.03, a tetragonal phase was determined for x = 0.05, and a single rhombohedral structure occurred at x = 0.08. The 0.92KNN-0.08BLZ ceramic exhibits a high and stable permittivity ( 1317, ± 15% variation) from 55 to 445 °C and low dielectric loss (≤ 6%) from 120 to 400 °C, which is hugely attractive for high-temperature capacitors. Activation energies of both high-temperature dielectric relaxation and dc conductivity first increase and then decline with the increase of BLZ, which might be attributed to the lattice distortion and concentration of oxygen vacancies.

Investigation of a miRNA-Induced Gene Silencing Technique in Petunia Reveals Alterations in miR173 Precursor Processing and the Accumulation of Secondary siRNAs from Endogenous Genes.

Directory of Open Access Journals (Sweden)

Yao Han

Full Text Available MIGS (miRNA-induced gene silencing is a straightforward and efficient gene silencing technique in Arabidopsis. It works by exploiting miR173 to trigger the production of phasiRNAs (phased small interfering RNAs. MIGS can be used in plant species other than Arabidopsis by co-expression of miR173 and target gene fragments fused to an upstream miR173 target site. However, the efficiency and technical mechanisms have not been thoroughly investigated in other plants. In this work, two vectors, pMIGS-chs and pMIGS-pds, were constructed and transformed into petunia plants. The transgenic plants showed CHS (chalcone synthase and PDS (phytoene desaturase gene-silencing phenotypes respectively, indicating that MIGS functions in petunia. MIGS-chs plants were used to investigate the mechanisms of this technique in petunia. Results of 5'- RACE showed that the miR173 target site was cleaved at the expected position and that endogenous CHS genes were cut at multiple positions. Small RNA deep sequencing analysis showed that the processing of Arabidopsis miR173 precursors in MIGS-chs transgenic petunia plants did not occur in exactly the same way as in Arabidopsis, suggesting differences in the machinery of miRNA processing between plant species. Small RNAs in-phase with the miR173 cleavage register were produced immediately downstream from the cleavage site and out-of-phase small RNAs were accumulated at relatively high levels from processing cycle 5 onwards. Secondary siRNAs were generated from multiple sites of endogenous CHS-A and CHS-J genes, indicating that miR173 cleavage induced siRNAs have the same ability to initiate siRNA transitivity as the siRNAs functioning in co-suppression and hpRNA silencing. On account of the simplicity of vector construction and the transitive amplification of signals from endogenous transcripts, MIGS is a good alternative gene silencing method for plants, especially for silencing a cluster of homologous genes with redundant

Investigation of a miRNA-Induced Gene Silencing Technique in Petunia Reveals Alterations in miR173 Precursor Processing and the Accumulation of Secondary siRNAs from Endogenous Genes.

Science.gov (United States)

Han, Yao; Zhang, Bin; Qin, Xiaoting; Li, Mingyang; Guo, Yulong

2015-01-01

MIGS (miRNA-induced gene silencing) is a straightforward and efficient gene silencing technique in Arabidopsis. It works by exploiting miR173 to trigger the production of phasiRNAs (phased small interfering RNAs). MIGS can be used in plant species other than Arabidopsis by co-expression of miR173 and target gene fragments fused to an upstream miR173 target site. However, the efficiency and technical mechanisms have not been thoroughly investigated in other plants. In this work, two vectors, pMIGS-chs and pMIGS-pds, were constructed and transformed into petunia plants. The transgenic plants showed CHS (chalcone synthase) and PDS (phytoene desaturase) gene-silencing phenotypes respectively, indicating that MIGS functions in petunia. MIGS-chs plants were used to investigate the mechanisms of this technique in petunia. Results of 5'- RACE showed that the miR173 target site was cleaved at the expected position and that endogenous CHS genes were cut at multiple positions. Small RNA deep sequencing analysis showed that the processing of Arabidopsis miR173 precursors in MIGS-chs transgenic petunia plants did not occur in exactly the same way as in Arabidopsis, suggesting differences in the machinery of miRNA processing between plant species. Small RNAs in-phase with the miR173 cleavage register were produced immediately downstream from the cleavage site and out-of-phase small RNAs were accumulated at relatively high levels from processing cycle 5 onwards. Secondary siRNAs were generated from multiple sites of endogenous CHS-A and CHS-J genes, indicating that miR173 cleavage induced siRNAs have the same ability to initiate siRNA transitivity as the siRNAs functioning in co-suppression and hpRNA silencing. On account of the simplicity of vector construction and the transitive amplification of signals from endogenous transcripts, MIGS is a good alternative gene silencing method for plants, especially for silencing a cluster of homologous genes with redundant functions.

Formation of perovskite-type compounds La0.5Ca0.5Mn1-xTixO3 (0≤x≤0.5)

International Nuclear Information System (INIS)

Wang, K.-Y.; Arcas, J.; Chen, D.-X.; Hernando, A.

1997-01-01

A series of perovskite-type compounds La 0.5 Ca 0.5 Mn 1-x Ti x O 3 is prepared by solid-state reaction. It is found that a single-phase tetragonal structure can be obtained for x≤0.5; the lattice parameters increase and magnetization at μ 0 H=0.2. T decreases with increasing x. (orig.)

Photometric, Spectroscopic, and X-ray Analysis of the Cool Algol BD+05 706

Science.gov (United States)

Torres, G.; Mader, J.; Marschall, L. A.; Neuhaeuser, R.; Duffy, A. S.

2000-12-01

BD+05 706 is an example of a rare class of a dozen or so interacting binaries called ``cool Algols", in which both components of the system are late-type stars. By contrast, the ``classical Algols" are systems in which the star transfering mass is of late spectral type, but the mass gainer is much hotter. BD+05 706 was shown previously to be eclipsing (Marschall, Torres & Neuhaeuser 1998, BAAS, 30, 835). In this paper we report our complete analysis of BVRI light curves for the system obtained at Gettysburg College Observatory, together with spectroscopy from the Harvard-Smithsonian Center for Astrophysics reported previously (Torres, Neuhaeuser & Wichmann 1998, AJ, 115, 2028), and X-ray observations obtained with the ROSAT satellite. Our light curve analysis indicates the presence of spots, most likely on the more massive, active component (primary), which change from season to season. Our results confirm the semi-detached nature of the system, and combined with the spectroscopy they have allowed us to obtain the most precise absolute masses and radii for any object of this class. Our X-ray light curve for BD+05 706 shows the primary eclipse clearly, but no sign of a secondary eclipse, confirming that the primary is the active star. Strong X-ray flares are also visible.

CHARACTERISTICS OF THE SECONDARY BUBBLE CLUSTER PRODUCED BY AN ELECTROHYDRAULIC SHOCK WAVE LITHOTRIPTER

Science.gov (United States)

Zhou, Yufeng; Qin, Jun; Zhong, Pei

2013-01-01

This study investigated the characteristics of the secondary bubble cluster produced by an electrohydraulic lithotripter using high-speed imaging and passive cavitation detection techniques. The results showed that (i) the discrepancy of the collapse time between near a flat rigid boundary and in a free field of the secondary bubble cluster was not as significant as that by the primary one; (ii) the secondary bubble clusters were small but in a high bubble density and nonuniform in distribution, and they did not expand and aggregate significantly near a rigid boundary; and (iii) the corresponding bubble collapse was weaker with few microjet formation and bubble rebound. By applying a strong suction flow near the electrode tip, the production of the secondary shock wave (SW) and induced bubble cluster could be disturbed significantly, but without influence on the primary ones. Consequently, stone fragmentation efficiency was reduced from 41.2 ± 7.1% to 32.2 ± 3.5% after 250 shocks (p <0.05). Altogether, these observations suggest that the secondary bubble cluster produced by an electrohydraulic lithotripter may contribute to its ability for effective stone fragmentation. PMID:22390990

Sequence and secondary structure of the mitochondrial small-subunit rRNA V4, V6, and V9 domains reveal highly species-specific variations within the genus Agrocybe.

Science.gov (United States)

Gonzalez, P; Labarère, J

1998-11-01

A comparative study of variable domains V4, V6, and V9 of the mitochondrial small-subunit (SSU) rRNA was carried out with the genus Agrocybe by PCR amplification of 42 wild isolates belonging to 10 species, Agrocybe aegerita, Agrocybe dura, Agrocybe chaxingu, Agrocybe erebia, Agrocybe firma, Agrocybe praecox, Agrocybe paludosa, Agrocybe pediades, Agrocybe alnetorum, and Agrocybe vervacti. Sequencing of the PCR products showed that the three domains in the isolates belonging to the same species were the same length and had the same sequence, while variations were found among the 10 species. Alignment of the sequences showed that nucleotide motifs encountered in the smallest sequence of each variable domain were also found in the largest sequence, indicating that the sequences evolved by insertion-deletion events. Determination of the secondary structure of each domain revealed that the insertion-deletion events commonly occurred in regions not directly involved in the secondary structure (i.e., the loops). Moreover, conserved sequences ranging from 4 to 25 nucleotides long were found at the beginning and end of each domain and could constitute genus-specific sequences. Comparisons of the V4, V6, and V9 secondary structures resulted in identification of the following four groups: (i) group I, which was characterized by the presence of additional P23-1 and P23-3 helices in the V4 domain and the lack of the P49-1 helix in V9 and included A. aegerita, A. chaxingu, and A. erebia; (ii) group II, which had the P23-3 helix in V4 and the P49-1 helix in V9 and included A. pediades; (iii) group III, which did not have additional helices in V4, had the P49-1 helix in V9 and included A. paludosa, A. firma, A. alnetorum, and A. praecox; and (iv) group IV, which lacked both the V4 additional helices and the P49-1 helix in V9 and included A. vervacti and A. dura. This grouping of species was supported by the structure of a consensus tree based on the variable domain sequences. The

Gd{sup 3+} doped Mn-Zn soft ferrite nanoparticles: Superparamagnetism and its correlation with other physical properties

Energy Technology Data Exchange (ETDEWEB)

Thakur, Prashant; Sharma, Rohit; Sharma, Vineet; Barman, P.B. [Department of Physics & Materials Science, Jaypee University of Information Technology, Waknaghat, Solan, Himachal Pradesh 173234 (India); Kumar, Manoj [Department of Physics & Materials Science, Jaypee Institute of Information Technology, Noida 201307 (India); Barman, Dipto [Gwangju Institute of Science & Technology, Gwangju (Korea, Republic of); Department of Computer Science & Engineering, Jaypee University of Information Technology, Waknaghat, Solan, Himachap Pradesh 173234 (India); Katyal, S.C. [Department of Physics & Materials Science, Jaypee Institute of Information Technology, Noida 201307 (India); Sharma, Pankaj, E-mail: pankaj.sharma@juit.ac.in [Department of Physics & Materials Science, Jaypee University of Information Technology, Waknaghat, Solan, Himachal Pradesh 173234 (India)

2017-06-15

Highlights: • Superparamagnetic nanoparticles of Gd doped Mn-Zn spinel ferrites synthesized by co-precipitation. • XRD and FTIR studies justify the formation of cubical spinel structure. • Maximum saturation magnetization and magnetic moment at x = 0.025. • PL spectra shows blue shift for x = 0.025, 0.075 and may be attributed to quantum confinement. - Abstract: Superparamagnetic nanoparticles are very important in biomedicine due to their various applications like drug delivery, gene delivery in the body and also used for hyperthermia. In the present work, superparamagnetic nanoparticles of Mn{sub 0.5}Zn{sub 0.5}Gd{sub x}Fe{sub 2-x}O{sub 4} (x = 0, 0.025, 0.050, 0.075, 0.1) ferrites have been prepared by co-precipitation method. Thorough characterizations (XRD, FTIR, FE-SEM, EDS, VSM and fluorescence spectroscopy) have proved the formation of cubical spinel superparamagnetic nanoparticles of soft ferrites. A cation distribution has been proposed for the determination of various important theoretical parameters for these samples. With the addition of Gd{sup 3+} nanoparticles have shown the superparamagnetism at room temperature confirmed by VSM analysis. Photoluminescence (PL) spectra shows a blue shift (for x = 0.025, 0.075) which may be due to quantum confinement.

An Action-Research Programme with Secondary Education Teachers on Teaching and Learning Photosynthesis

Science.gov (United States)

Domingos-Grilo, Paula; Reis-Grilo, Carlos; Ruiz, Constantino; Mellado, Vicente

2012-01-01

We describe part of an action-research programme in Spain which was based on metacognitive reflection. The participants were four science teachers in a secondary school during the 2004-05 and 2005-06 academic years. During the study, they each analysed their own pupils' alternative ideas on photosynthesis and their teaching methods as recorded in…

Primary and secondary exercise dependence in a community-based sample of road race runners.

Science.gov (United States)

Cook, Brian; Karr, Trisha M; Zunker, Christie; Mitchell, James E; Thompson, Ron; Sherman, Roberta; Crosby, Ross D; Cao, Li; Erickson, Ann; Wonderlich, Stephen A

2013-10-01

The purpose of our study was to examine exercise dependence (EXD) in a large community-based sample of runners. The secondary purpose of this study was to examine differences in EXD symptoms between primary and secondary EXD. Our sample included 2660 runners recruited from a local road race (M age = 38.78 years, SD = 10.80; 66.39% women; 91.62% Caucasian) who completed all study measures online within 3 weeks of the race. In this study, EXD prevalence was lower than most previously reported rates (gamma = .248, p < .001) and individuals in the at-risk for EXD category participated in longer distance races, F(8,1) = 14.13, p = .01, partial eta squared = .05. Group differences were found for gender, F(1,1921) 8.08, p = .01, partial eta squared = .004, and primary or secondary group status, F(1,1921) 159.53, p = .01, partial eta squared = .077. Implications of primary and secondary EXD differences and future research are discussed.

Screening for secondary endocrine hypertension in young patients.

Science.gov (United States)

Trifanescu, Raluca; Carsote, Mara; Caragheorgheopol, Andra; Hortopan, Dan; Dumitrascu, Anda; Dobrescu, Mariana; Poiana, Catalina

2013-06-01

Secondary endocrine hypertension accounts for 5-12% of hypertension's causes. In selected patients (type 2 diabetes mellitus, sleep apnea syndrome with resistant hypertension, sudden deterioration in hypertension control), prevalence could be higher. To present etiology of endocrine secondary hypertension in a series of patients younger than 40 years at hypertension's onset. Medical records of 80 patients (39M/41F), aged 30.1 ± 8.2 years (range: 12-40 years), with maximum systolic blood pressure=190.4 ± 29.2 mm Hg, range: 145-300 mm Hg, maximum diastolic blood pressure=107.7 ± 16.9 mm Hg, range: 80-170 mm Hg) referred by cardiologists for endocrine hypertension screening were retrospectively reviewed. Cardiac and renal causes of secondary hypertension were previously excluded. In all patients, plasma catecholamines were measured by ELISA and plasma cortisol by immunochemiluminescence. Orthostatic aldosterone (ELISA) and direct renin (chemiluminescence) were measured in 48 patients. Secondary endocrine hypertension was confirmed in 16 out of 80 patients (20%). Primary hyperaldosteronism was diagnosed in 7 (4M/3F) out of 48 screened patients (14.6%). i.e. 8.75% from whole group: 5 patients with adrenal tumors (3 left/2 right), 2 patients with bilateral adrenal hyperplasia; all patients were hypokalemic at diagnostic (average nadir K+ levels = 2.5 ± 0.5 mmol/L); four patients were hypokalaemic on diuretic therapy (indapamidum); other 3 patients were hypokalaemic in the absence of diuretic therapy. Cushing's syndrome was diagnosed in 6 patients (7.5%): subclinical Cushing due to 4 cm right adrenal tumour - n = 1, overt ACTH-independent Cushing's syndrome due to: macronodular adrenal hyperplasia associated with primary hyperparathyroidism - n = 1; due to adrenal carcinoma - n = 1; due to adrenal adenomas - n = 2; Cushing's disease - n = 1). Pheochromocytomas were diagnosed in 3 patients (3.75%). Primary hyperaldosteronism was the most frequent cause of secondary

Rtools: a web server for various secondary structural analyses on single RNA sequences.

Science.gov (United States)

Hamada, Michiaki; Ono, Yukiteru; Kiryu, Hisanori; Sato, Kengo; Kato, Yuki; Fukunaga, Tsukasa; Mori, Ryota; Asai, Kiyoshi

2016-07-08

The secondary structures, as well as the nucleotide sequences, are the important features of RNA molecules to characterize their functions. According to the thermodynamic model, however, the probability of any secondary structure is very small. As a consequence, any tool to predict the secondary structures of RNAs has limited accuracy. On the other hand, there are a few tools to compensate the imperfect predictions by calculating and visualizing the secondary structural information from RNA sequences. It is desirable to obtain the rich information from those tools through a friendly interface. We implemented a web server of the tools to predict secondary structures and to calculate various structural features based on the energy models of secondary structures. By just giving an RNA sequence to the web server, the user can get the different types of solutions of the secondary structures, the marginal probabilities such as base-paring probabilities, loop probabilities and accessibilities of the local bases, the energy changes by arbitrary base mutations as well as the measures for validations of the predicted secondary structures. The web server is available at http://rtools.cbrc.jp, which integrates software tools, CentroidFold, CentroidHomfold, IPKnot, CapR, Raccess, Rchange and RintD. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

Depairing current density of Ba0.5K0.5Fe1.95Co0.05As2 microbridges with nanoscale thickness

International Nuclear Information System (INIS)

Li, Jun; Yuan, Jie; Ge, Jun-Yi; Ji, Min; Feng, Hai-Luke; Yuan, Ya-Hua; Hatano, Takeshi; Vanacken, Johan; Yamaura, Kazunari; Wang, Hua-Bing

2014-01-01

Highlights: • The critical current density of Ba 0.5 K 0.5 Fe 1.95 Co 0.05 As 2 microbridges is 7.9 MA/cm 2 at 21 K. • The critical current is in consistence with the Ginzburg–Landau depairing limit. • The depairing current density is less than that of impurity-free crystal. - Abstract: We investigated the depairing current density of Ba 0.5 K 0.5 Fe 1.95 Co 0.05 As 2 microbridges with width of 2 μm and thickness of 150 nm. The current vs. voltage characteristics of the microbridges show a Josephson-like behavior with the obvious hysteresis. The critical current density was observed as J c = 7.9 MA/cm 2 at temperature 21 K, which is consistent with the Ginzburg–Landau depairing limit. However, the depairing current density is less than that of impurity-free crystal, although the Co ions provide additional pinning centers within the superconducting Fe 2 As 2 layers. The Co impurity also enhances the anisotropic factor of the critical current density by 1.3 (1 T) or 1.7 (3 T)

Results of the secondary side chemical cleaning of the steam generators

International Nuclear Information System (INIS)

Doma, A.; Patek, G.

2001-01-01

A significant amount of deposit has developed on the secondary side of the heat transfer tubes of the steam generators (SG) of the Paks Nuclear Power Plant units in course of the years. More than 99.5% of the deposit is made up of magnetite (Fe 3 O 4 ) generated in the secondary circuit of the power plant. Those deposits lead to the decrease of the heat transfer. Even more important is its role from the point of view of operational reliability of the steam generators, leak tightness between the primary and secondary sides. The first series of cleaning took place following 8-9 years of operation of the units. Following the first cleaning cycle the transport of the corrosion products into the steam generators did not change, and thus obviously new cleaning was required. Periodical cleaning of the steam generators shall be assured. (R.P.)

Studies on the properties of poly(ethylene oxide) R-150 water-swollen hydrogel formed by irradiation

International Nuclear Information System (INIS)

Yang Zhanshan; Zhu Nankang; Yang Shuqin; Qiang Yizhong

2000-01-01

The physical and chemical properties of PEO R-150 water-swollen hydrogel films formed by electron beam irradiation are studied and compared with PEO R-150 hydrogel films. The experimental results show that the irradiation dose and mass fraction of the polymer do not produce a significant effect on the gel fraction, of the PEO R-150 water-swollen hydrogel films (P>0.05). The degrees of swelling of the PEO R-150 water-swollen hydrogel films decrease as the irradiation dose increasing (P 0.05). The results indicate that the saturant crosslinking density, the lowest degree of swelling of the PEO R-150 water-swollen hydrogel films produce and unfavorable effect on their machinery strength

ACP/R3000 processors in data acquisition systems

International Nuclear Information System (INIS)

Deppe, J.; Areti, H.; Atac, R.

1989-02-01

We describe ACP/R3000 processor based data acquisition systems for high energy physics. This VME bus compatible processor board, with a computational power equivalent to 15 VAX 11/780s or better, contains 8 Mb of memory for event buffering and has a high speed secondary bus that allows data gathering from front end electronics. 2 refs., 3 figs

2018-05-09T13:20:33Z https://www.ajol.info/index.php/all/oai oai:ojs ...

African Journals Online (AJOL)

article/67957 2018-05-09T13:20:33Z ajtcam:ART Medicinal Plants Traditionally Used In Mali for Dysmenorrhea Sanogo, R Dysmenorrhea; Maytenus senegalensis; Stereospermum kunthianum; Trichilia emetica; Mali Dysmenorrhea is painful ...

Synthesis and growth mechanism of Zn0.5Cd0.5S nanohexagon dendrite

Science.gov (United States)

Yu, Wen; Fang, Pengfei; Wang, Shaojie

2014-12-01

Hierarchical Zn0.5Cd0.5S nanohexagon dendrites were synthesized by a one-step hydrothermal method. The Zn0.5Cd0.5S nanohexagon dendrites were made up of nanohexagons with a side length of about 90 nm. The nanohexagons were regularly arranged forming as embranchments which were parallel to each other along certain hexagonal directions. Furthermore, these embranchments made up primary trunks shaping as dendrites. The growth mechanism of Zn0.5Cd0.5S nanohexagon dendrites was proposed in which molecular soft template and lowest energy principle played key roles. By adjusting the composition of the reactants, a series of ZnxCd1-xS solid solutions could be obtained. The morphology of the synthesized ZnxCd1-xS depended much on the x value. The UV-vis spectra absorb edges of the ZnxCd1-xS samples continuously shifted indicating the changes of the band gap.

Freeze drying synthesis of LiNi0.5Mn0.5O2 cathode materials

International Nuclear Information System (INIS)

Shlyakhtin, O.A.; Yoon, Young Soo; Choi, Sun Hee; Oh, Young-Jei

2004-01-01

The influence of several processing conditions on the phase formation and electrochemical performance of LiNi 0.5 Mn 0.5 O 2 powders, obtained by freeze drying method, is studied. Thermal processing in pellets at maximum heating rate promotes better crystallographic ordering of hexagonal LiNi 0.5 Mn 0.5 O 2 and maximum capacity values irrespectively of chemical composition of the precursor. Instead, intense mechanical processing of precursors exerts considerable negative effect on the electrochemical performance. Cathode materials containing superstoichiometric amount of lithium (Li 1.3 Mn 0.5 Ni 0.5 O 2+δ ) demonstrate reversible capacity values up to 190 mAh/g between 2.5 and 4.6 V

Histone acetyltransferase TGF-1 regulates Trichoderma atroviride secondary metabolism and mycoparasitism.

Science.gov (United States)

Gómez-Rodríguez, Elida Yazmín; Uresti-Rivera, Edith Elena; Patrón-Soberano, Olga Araceli; Islas-Osuna, María Auxiliadora; Flores-Martínez, Alberto; Riego-Ruiz, Lina; Rosales-Saavedra, María Teresa; Casas-Flores, Sergio

2018-01-01

Some filamentous fungi of the Trichoderma genus are used as biocontrol agents against airborne and soilborne phytopathogens. The proposed mechanism by which Trichoderma spp. antagonizes phytopathogens is through the release of lytic enzymes, antimicrobial compounds, mycoparasitism, and the induction of systemic disease-resistance in plants. Here we analyzed the role of TGF-1 (Trichoderma Gcn Five-1), a histone acetyltransferase of Trichoderma atroviride, in mycoparasitism and antibiosis against the phytopathogen Rhizoctonia solani. Trichostatin A (TSA), a histone deacetylase inhibitor that promotes histone acetylation, slightly affected T. atroviride and R. solani growth, but not the growth of the mycoparasite over R. solani. Application of TSA to the liquid medium induced synthesis of antimicrobial compounds. Expression analysis of the mycoparasitism-related genes ech-42 and prb-1, which encode an endochitinase and a proteinase, as well as the secondary metabolism-related genes pbs-1 and tps-1, which encode a peptaibol synthetase and a terpene synthase, respectively, showed that they were regulated by TSA. A T. atroviride strain harboring a deletion of tgf-1 gene showed slow growth, thinner and less branched hyphae than the wild-type strain, whereas its ability to coil around the R. solani hyphae was not affected. Δtgf-1 presented a diminished capacity to grow over R. solani, but the ability of its mycelium -free culture filtrates (MFCF) to inhibit the phytopathogen growth was enhanced. Intriguingly, addition of TSA to the culture medium reverted the enhanced inhibition growth of Δtgf-1 MFCF on R. solani at levels compared to the wild-type MFCF grown in medium amended with TSA. The presence of R. solani mycelium in the culture medium induced similar proteinase activity in a Δtgf-1 compared to the wild-type, whereas the chitinolytic activity was higher in a Δtgf-1 mutant in the absence of R. solani, compared to the parental strain. Expression of mycoparasitism

Histone acetyltransferase TGF-1 regulates Trichoderma atroviride secondary metabolism and mycoparasitism.

Directory of Open Access Journals (Sweden)

Elida Yazmín Gómez-Rodríguez

Full Text Available Some filamentous fungi of the Trichoderma genus are used as biocontrol agents against airborne and soilborne phytopathogens. The proposed mechanism by which Trichoderma spp. antagonizes phytopathogens is through the release of lytic enzymes, antimicrobial compounds, mycoparasitism, and the induction of systemic disease-resistance in plants. Here we analyzed the role of TGF-1 (Trichoderma Gcn Five-1, a histone acetyltransferase of Trichoderma atroviride, in mycoparasitism and antibiosis against the phytopathogen Rhizoctonia solani. Trichostatin A (TSA, a histone deacetylase inhibitor that promotes histone acetylation, slightly affected T. atroviride and R. solani growth, but not the growth of the mycoparasite over R. solani. Application of TSA to the liquid medium induced synthesis of antimicrobial compounds. Expression analysis of the mycoparasitism-related genes ech-42 and prb-1, which encode an endochitinase and a proteinase, as well as the secondary metabolism-related genes pbs-1 and tps-1, which encode a peptaibol synthetase and a terpene synthase, respectively, showed that they were regulated by TSA. A T. atroviride strain harboring a deletion of tgf-1 gene showed slow growth, thinner and less branched hyphae than the wild-type strain, whereas its ability to coil around the R. solani hyphae was not affected. Δtgf-1 presented a diminished capacity to grow over R. solani, but the ability of its mycelium -free culture filtrates (MFCF to inhibit the phytopathogen growth was enhanced. Intriguingly, addition of TSA to the culture medium reverted the enhanced inhibition growth of Δtgf-1 MFCF on R. solani at levels compared to the wild-type MFCF grown in medium amended with TSA. The presence of R. solani mycelium in the culture medium induced similar proteinase activity in a Δtgf-1 compared to the wild-type, whereas the chitinolytic activity was higher in a Δtgf-1 mutant in the absence of R. solani, compared to the parental strain. Expression

STUDYING THE SECONDARY STRUCTURE OF ACCESSION NUMBER USING CETD MATRIX

Directory of Open Access Journals (Sweden)

Anamika Dutta

2016-10-01

Full Text Available This paper, we have tried to analyze about the Secondary Structure of nucleotide sequences of rice. The data have been collected from NCBI (National Centre for Biotechnology Information using Nucleotide as data base. All the programs were developed using R programming language using “sequinr” package. Here, we have used CETD matrix method to study the prediction. The conclusions are drawn accordingly.

The impact of building recirculation rates on secondary organic aerosols generated by indoor chemistry

DEFF Research Database (Denmark)

Zuraimi, M.S.; Weschler, Charles J.; Tham, K.W.

2007-01-01

Numerous investigators have documented increases in the concentrations of airborne particles as a consequence of ozone/terpene reactions in indoor environments. This study examines the effect of building recirculation rates on the concentrations of secondary organic aerosol (SOA) resulting from r...

A novel approach to secondary defect reduction in separation by implantation of oxygen (SIMOX) material

Energy Technology Data Exchange (ETDEWEB)

Ellingboe, S.L.; Ridgway, M.C. [Australian National Univ., Canberra, ACT (Australia). Research School of Physical Sciences

1993-12-31

The formation of a buried SiO{sub 2} layer in Si for increased radiation hardness, dielectric isolation, and/or higher operating speeds in Si devices has been studied extensively. In the present report, a novel method for improving the final defect structure of SIMOX material is demonstrated for the first time. The concept of ion-beam defect-engineering (IBDE) introduced by Wang et al has been utilised. If defects are introduced at a depth R{sub 1} by irradiation with energetic ions into samples which were previously damaged at a depth R{sub 2}, it is possible to alter the properties of the defects at R{sub 2}, reduce or eliminate damage at R{sub 2}, and/or create gettering sites for defects at R{sub 1} . To elucidate the mechanisms responsible for the secondary defect reduction in annealed SIMOX material, unannealed samples were implanted with Si ions at various energies, while keeping the nuclear energy deposition constant at two depths. It was observed that after annealing, even greater changes in the defect structure are evident. It has been demonstrated that pre-anneal Si irradiation in O-implanted Si can reduce secondary defect formation. Both the depth and amount of damage created are crucial to the success of the Si implantation. 5 refs., 1 tab., 2 figs.

A novel approach to secondary defect reduction in separation by implantation of oxygen (SIMOX) material

Energy Technology Data Exchange (ETDEWEB)

Ellingboe, S L; Ridgway, M C [Australian National Univ., Canberra, ACT (Australia). Research School of Physical Sciences

1994-12-31

The formation of a buried SiO{sub 2} layer in Si for increased radiation hardness, dielectric isolation, and/or higher operating speeds in Si devices has been studied extensively. In the present report, a novel method for improving the final defect structure of SIMOX material is demonstrated for the first time. The concept of ion-beam defect-engineering (IBDE) introduced by Wang et al has been utilised. If defects are introduced at a depth R{sub 1} by irradiation with energetic ions into samples which were previously damaged at a depth R{sub 2}, it is possible to alter the properties of the defects at R{sub 2}, reduce or eliminate damage at R{sub 2}, and/or create gettering sites for defects at R{sub 1} . To elucidate the mechanisms responsible for the secondary defect reduction in annealed SIMOX material, unannealed samples were implanted with Si ions at various energies, while keeping the nuclear energy deposition constant at two depths. It was observed that after annealing, even greater changes in the defect structure are evident. It has been demonstrated that pre-anneal Si irradiation in O-implanted Si can reduce secondary defect formation. Both the depth and amount of damage created are crucial to the success of the Si implantation. 5 refs., 1 tab., 2 figs.

Performance evaluation of Siemens E.CAM(R) SPECT system at Korle-Bu Teaching Hospital (Ghana)

International Nuclear Information System (INIS)

Sosu, E.K.; Hasford, F.; Amuasi, J.H.

2011-01-01

Performance evaluation tests on Siemens e.cam(R) Signature Series Single Photon Emission Computed Tomography (SPECT)System at Korle-Bu Teaching Hospital (Ghana) were conducted for compliance with Manufacturer's specifications and user's requirements. The tests were performed according to National Electrical Manufacturer's Association protocols, and different measuring instruments and phantoms containing 99m-Tc were used. Extrinsic uniformity, system energy resolution, system spatial resolution (without scattering), detector shield leakage and system planar sensitivity were evaluated. The system energy resolution measured was 9.38 % as against manufacturer's specification of ≤ 9.9 %, Planar sensitivity value measured was 232.92 c/min/mCi while manufacturers' specification was 202 c/min/mCi, and detector shield leakage values measured were 0.001 %, 0.002 % and 0.025 % against an accepted value of < 1 %. The performance evaluation confirmed that the system met requirements for clinical nuclear medicine imaging, and the values could be used as database for future quality control measurements. (au)

FY 2000 report on the results of the regional consortium R and D project - Regional consortium energy R and D field. First year report. R and D of new composite polymer electrolyte for battery; 2000 nendo chiiki consortium kenkyu kaihatsu jigyo - chiiki consortium energy kenkyu kaihatsu bun'ya. Denchiyo shinki fukugo polymer kei denkaishitsu no kenkyu kaihatsu (dai 1 nendo) seika hokokusho

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-03-01

The development was proceeded with of new composite polymer electrolyte for Li secondary battery. The ultimate target of the development using this electrolyte is to get Li secondary battery markedly improved in safety/reliability which works at low temperature and controls thermal runaway. The composite polymer base electrolyte is composed of high molecular weight polyethylene oxide copolymer, ethylene oxide oligomer and Li salt, and it is finally cross-linked by heat or light. Studies were made in the following 6 fields: 1) R and D of the creation and optimization of new composite polymer electrolyte; 2) R and D of the commercialization of composite polymer electrolyte battery; 3) R and D on the safety of composite polymer electrolyte; 4) study of the synthesis of new electrolyte and catalytic activity of electrolyte-electrode interface; 5) R and D on polymer/oligomer composite electrolyte; and 6) comprehensive investigational research. (NEDO)

Smoking Prevalence and Related Factors Among Secondary and High School Students in Tokat Province

Directory of Open Access Journals (Sweden)

Gizem Emekdar

2017-03-01

Full Text Available Smoking Prevalence and Related Factors Among Secondary and High School Students in Tokat Province Objective: The tobacco epidemic is one of the biggest public health threats in the world. The majority of smokers in the adolescent group has started smoking at early ages. Smoking prevalence among adolescents are reported to be approximately 10%. This study was aimed to determine the prevalence of smoking and related factors among secondary and high school students in Tokat province. Method: Population of this cross-sectional study consists of secondary and high school students in Tokat. Sample size was calculated as 1072 by using proportional stratified cluster sampling method according to type of school, gender and age. The study has been completed with 1069 students (secondary school: 557, high school: 512. Sociodemographic characteristics and the smoking habits of students were determined through questionaries. The students who smoking at least one cigarette in a day were accepted as smokers. Results: 50.9% of secondary school students were male, mean age was 12.1±1.3, 74.5% lived in city, prevalence of smoking was 10.8% (male:17.3%, female:4% and it was higher for students with <70 (16.3% average school grades than those with ≥70 (6.8% (p<0.05. 52.3% of high school students were female, mean age was 16.2±1.3, 80.7% lived in city, prevalence of smoking was 18% (male:29.9%, female:7.1% and it was higher for students which have secondary or above maternal education level (23.8% than those students which have lower maternal education level (15.7%; higher in those whom parents live seperate or have died (42.3% than those whom parents live together (16.7%; higher in those that have average school grades <70 (23.8% than those with ≥70 (11.3% (p<0.05. Place of residence, income level and profession of parents were not significant effect on smoking prevalence. The most common cause of start smoking was curiosity (42.4%. Conclusions: Nearly one in

Crystal growth iron based pnictide compounds; Kristallzuechtung eisenbasierter Pniktidverbindungen

Energy Technology Data Exchange (ETDEWEB)

Nacke, Claudia

2012-11-15

The present work is concerned with selected crystal growth method for producing iron-based superconductors. The first part of this work introduces significant results of the crystal growth of BaFe{sub 2}As{sub 2} and the cobalt-substituted compound Ba(Fe{sub 1-x}Co{sub x}){sub 2}As{sub 2} with x{sub Nom} = 0.025, 0.05, 0.07, 0.10 and 0.20. For this purpose a test procedure for the vertical Bridgman method was developed. The second part of this work contains substantial results for growing a crystal of LiFeAs and the nickel-substituted compound Li{sub 1-δ}Fe{sub 1-x}Ni{sub x}As with x{sub Nom} = 0.015, 0.025, 0.05, 0.06, 0.075 and 0.10. For this purpose a test procedure for the melt flow process has been developed successfully. [German] Die vorliegende Arbeit befasst sich mit ausgewaehlten Kristallzuechtungsverfahren zur Herstellung eisenbasierter Supraleiter. Der erste Teil dieser Arbeit fuehrt wesentliche Ergebnisse der Kristallzuechtung von BaFe{sub 2}As{sub 2} sowie der Cobalt-substituierten Verbindung Ba(Fe{sub 1-x}Co{sub x}){sub 2}As{sub 2} mit x{sub Nom} =0.025, 0.05, 0.07, 0.10 und 0.20 auf. Hierzu wurde eine Versuchsdurchfuehrung fuer das vertikale Bridgman-Verfahren konzipiert, mit welcher erfolgreich Kristalle dieser Zusammensetzungen gezuechtet wurden. Der zweite Teil dieser Arbeit enthaelt wesentliche Ergebnisse zur Kristallzuechtung von LiFeAs sowie der Nickel-substituierten Verbindung Li{sub 1-δ}Fe{sub 1-x}Ni{sub x}As mit x{sub Nom} = 0.015, 0.025, 0.05, 0.06, 0.075 und 0.10. Hierfuer wurde erfolgreich eine Versuchsdurchfuehrung fuer das Schmelzfluss-Verfahren entwickelt.

Hepatic transcriptome analysis of juvenile GIFT tilapia (Oreochromis niloticus), fed diets supplemented with different concentrations of resveratrol.

Science.gov (United States)

Zheng, Yao; Wu, Wei; Hu, Gengdong; Zhao, Zhixiang; Meng, Shunlong; Fan, Limin; Song, Chao; Qiu, Liping; Chen, Jiazhang

2018-01-01

The GIFT (Genetically Improved Farmed Tilapia) tilapia, Oreochromis niloticus, is cultured widely for the production of freshwater fish in China. Streptococcosis, which is related to pathogenic infections, occurs frequently in juvenile and adult female GIFT individuals. Resveratrol (RES) has been used in feed to control these infections in freshwater tilapia. To address the effects of RES on tilapia, we used high-throughput RNA sequencing technology (RNA-Seq, HiSeq. 2500) to explore the global transcriptomic response and specific involvement of hepatic mRNA of juvenile O. niloticus fed with diets containing different concentrations of (0, 0.025, 0.05, and 0.1g/kg) RES. A total of > 24,513,018 clean reads were generated and then assembled into 23,244 unigenes. The unigenes were annotated by comparing them against non-redundant protein sequence (Nr), non-redundant nucleotide (Nt), Swiss-Prot, Pfam, Gene Ontology database (GO), Clusters of Orthologous Groups (COG) and Kyoto Encyclopedia of Genes and Genomes (KEGG) databases, and 12,578 unigenes were annotated to the GO database. A total of 1444 (0.025g/kg RES), 1526 (0.05g/kg RES), and 3135 (0.1g/kg RES) genes were detected as significant differentially expressed genes (DEGs), when compared with the controls. A total of 6 (0.025 vs 0.05g/kg RES), 19 (0.025 vs 0.1g/kg RES), and 124 (0.05 vs 0.1g/kg RES) genes were detected as significant DEGs. Six genes, including dnah7x1, sox4, fam46a, hsp90a, ddit4, and nmrk2, were associated with an immune response. These findings provide information on the innate immunity of GIFT and might contribute to the development of strategies for the effective management of diseases and long-term sustainability of O. niloticus culture. Copyright © 2017 Elsevier Inc. All rights reserved.

Physical, chemical, and nutrient data collected from CTD and bottle casts from the R/V HERMANO GINES from the continental shelf of Venezuela in support of the Carbon Retention in a Colored Ocean (CARIACO) project from 10 April 2007 to 05 August December 2008 (NODC Accession 0056729)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — CTD and bottle data were collected from R/V HERMANO GINES on the continental shelf of Venezuela from 10 April 2007 to 05 August 2008. Data were collected by the...

Crystal-fields at rare-earth sites in R2Fe14B compounds

International Nuclear Information System (INIS)

Adam, S.; Adam, G.; Burzo, E.

1985-12-01

Crystal-field effects are expected to be important in R 2 Fe 14 B compounds. Within a model-independent approach, it is proved that four distinct rare-earth sites exist with respect to the crystalline electric fields, namely, R(4f; z=0), R(4f; z=0.5 c), R(4g; z=0), and R(4g; z=0.5 c), and relationships are established between the corresponding crystal-fields coefficients. Further, generalized Stevens parametrizations of the crystal field coefficients are derived at three levels of approximation for the interatomic forces inside the crystal. A crystal lattice dressing effect upon the radial electronic integrals is found to occur, the magnitude of which depends on the deviation of the interatomic forces from Coulombian. Finally, computation of crystal-field coefficients in Nd 2 Fe 14 B leads to results which raise questions about the validity of the simple Coulomb point-charge model. (author)

ZnO nanorods/ZnS.(1,6-hexanediamine)0.5 hybrid nanoplates hierarchical heteroarchitecture with improved electrochemical catalytic properties for hydrazine

Science.gov (United States)

Wu, Zhengcui; Wu, Yaqin; Pei, Tonghui; Wang, Huan; Geng, Baoyou

2014-02-01

Novel hierarchical heteronanostructures of ZnO nanorods/ZnS.(HDA)0.5 (HDA = 1,6-hexanediamine) hybrid nanoplates on a zinc substrate are successfully synthesized on a large scale by combining hydrothermal growth (for ZnO nanorods) and liquid chemical conversion (for ZnS.(HDA)0.5 nanoplates) techniques. The formation of ZnS.(HDA)0.5 hybrid nanoplates branches takes advantage of the preferential binding of 1,6-hexanediamine on specific facets of ZnS, which makes the thickening rate much lower than the lateral growth rate. The ZnS.(HDA)0.5 hybrid nanoplates have a layered structure with 1,6-hexanediamine inserted into interlayers of wurtzite ZnS through the bonding of nitrogen. The number density and thickness of the secondary ZnS.(HDA)0.5 nanoplates can be conveniently engineered by variation of the sulfur source and straightforward adjustment of reactant concentrations such as 1,6-hexanediamine and the sulfur source. The fabricated ZnO/ZnS.(HDA)0.5 heteronanostructures show improved electrochemical catalytic properties for hydrazine compared with the primary ZnO nanorods. Due to its simplicity and efficiency, this approach could be similarly used to fabricate varieties of hybrid heterostructures made of materials with an intrinsic large lattice mismatch.Novel hierarchical heteronanostructures of ZnO nanorods/ZnS.(HDA)0.5 (HDA = 1,6-hexanediamine) hybrid nanoplates on a zinc substrate are successfully synthesized on a large scale by combining hydrothermal growth (for ZnO nanorods) and liquid chemical conversion (for ZnS.(HDA)0.5 nanoplates) techniques. The formation of ZnS.(HDA)0.5 hybrid nanoplates branches takes advantage of the preferential binding of 1,6-hexanediamine on specific facets of ZnS, which makes the thickening rate much lower than the lateral growth rate. The ZnS.(HDA)0.5 hybrid nanoplates have a layered structure with 1,6-hexanediamine inserted into interlayers of wurtzite ZnS through the bonding of nitrogen. The number density and thickness of the

Selective blockade of leukotriene production by a single dose of the FPL 64170XX 0.5% enema in active ulcerative colitis

DEFF Research Database (Denmark)

Kjeldsen, J; Laursen, L S; Hillingsø, Jens

1995-01-01

5-Lipoxygenase products of arachidonic acid metabolism are thought to play a central role in the secondary amplification of the inflammatory response of several inflammatory diseases, including ulcerative colitis. FPL 64170XX is a selective inhibitor of the enzyme 5-lipoxygenase. Concentrations...... containing 0.5% of FPL 64170XX. Repeated measures analysis of leukotriene B4, after adjusting for baseline, showed a significant treatment effect (P = 0.0014). The concentration of leukotriene B4 from rectal dialysates in patients receiving the active drug dropped to 15% (95% confidence interval 5......-40%) of the placebo level in the second dialysis following administration of FPL 64170XX 0.5%. By contrast, prostaglanding E2 concentrations doubled (P = 0.0068) in patients receiving FPL 64170XX 0.5% with no change in the placebo group. These findings demonstrate that a single dose of FPL 64170XX 0.5% enema...

Synthesis and characterization of superionic (LiBr)_0_._5(AlSiO)_0_._5

International Nuclear Information System (INIS)

Aziz K Jahja; Safei Purnama

2010-01-01

Materials of LiBr silicate aluminum ionic conductor have been prepared by powder metallurgy method in which 0.5 mole of LiBr powder is mixed with about 0.5 mole silicate aluminum in liquid medium of aquadest. After mixing and homogenization, the samples are dried, compacted and heated at 600 °C for 1 hour. Characterization of materials structure was carried out by X-Ray diffraction, ionic conductivity was measured by LCR meter with frequency range of 10"-"1 to 10"5 Hz at room temperature. Results of measurement show the (LiBr)_0_._5(AlSiO)_0_._5 conductor has the structure of both LiBr and of silicate aluminum. (LiBr)_0_._5(AlSiO)_0_._5 has the highest ionic conductivity in the order of 10"-"3 S.cm"-"1 while the ionic conductivity of LiBr is found to be about 10"-"4 S.cm"-"1 and that of silicate aluminum is about 10"-"6 S.cm"-"1, all measured at room temperature. (author)

Short-term efficacy of surgical treatment of secondary hyperparathyroidism.

Science.gov (United States)

Liang, Y; Sun, Y; Ren, L; Qi, X-W; Li, Y; Zhang, F

2015-10-01

We wished to explore short-term efficacy of surgical treatment of secondary hyperparathyroidism in patients with the end-stage renal disease. The treatment methods were subtotal or total parathyroidectomy, or total parathyroidectomy and autotransplantation. 63 patients with secondary hyperparathyroidism were randomly divided into three groups which were respectively treated with subtotal parathyroidectomy (SPTX group), total parathyroidectomy (TPTX group), or total parathyroidectomy and autotransplantation (TPTX+AT group). The surgical outcomes included operating time, transoperative bleeding volume, length of stay, and cost of hospitalization. In addition, complication (e.g., postoperative wound infection, hematoma, hypocalcemia in perioperative period) rates were compared among groups. Blood levels of calcium and parathyroid hormone were assessed before the surgery, and 1 day, 1 months, 3 months and 6 months after the surgery. The follow-up period comprised 6 months. Surgical outcomes were the lowest in SPTX group and the highest in in TPTX+AT group. There were no significant differences among groups in treatment efficacy. Complication rates were also comparable among the three groups. The occurrence of hypocalcemia was the lowest in SPTX group (p < 0.05 vs. other groups). However, postoperative relapse rate was the highest in this group (p < 0.05 vs. other groups). There were no correlations between the levels of blood calcium and PTH preoperatively and postoperatively. Appropriate surgical treatment is selected in accordance with the patient's condition and willingness, with the attention paid to the prevention of hypocalcemia.

Evaluation of the suitability of free-energy minimization using nearest-neighbor energy parameters for RNA secondary structure prediction

Directory of Open Access Journals (Sweden)

Cobaugh Christian W

2004-08-01

Full Text Available Abstract Background A detailed understanding of an RNA's correct secondary and tertiary structure is crucial to understanding its function and mechanism in the cell. Free energy minimization with energy parameters based on the nearest-neighbor model and comparative analysis are the primary methods for predicting an RNA's secondary structure from its sequence. Version 3.1 of Mfold has been available since 1999. This version contains an expanded sequence dependence of energy parameters and the ability to incorporate coaxial stacking into free energy calculations. We test Mfold 3.1 by performing the largest and most phylogenetically diverse comparison of rRNA and tRNA structures predicted by comparative analysis and Mfold, and we use the results of our tests on 16S and 23S rRNA sequences to assess the improvement between Mfold 2.3 and Mfold 3.1. Results The average prediction accuracy for a 16S or 23S rRNA sequence with Mfold 3.1 is 41%, while the prediction accuracies for the majority of 16S and 23S rRNA structures tested are between 20% and 60%, with some having less than 20% prediction accuracy. The average prediction accuracy was 71% for 5S rRNA and 69% for tRNA. The majority of the 5S rRNA and tRNA sequences have prediction accuracies greater than 60%. The prediction accuracy of 16S rRNA base-pairs decreases exponentially as the number of nucleotides intervening between the 5' and 3' halves of the base-pair increases. Conclusion Our analysis indicates that the current set of nearest-neighbor energy parameters in conjunction with the Mfold folding algorithm are unable to consistently and reliably predict an RNA's correct secondary structure. For 16S or 23S rRNA structure prediction, Mfold 3.1 offers little improvement over Mfold 2.3. However, the nearest-neighbor energy parameters do work well for shorter RNA sequences such as tRNA or 5S rRNA, or for larger rRNAs when the contact distance between the base-pairs is less than 100 nucleotides.

Structural distortions in Sr3-xAxMO4F (A=Ca, Ba; M=Al, Ga, In) anti-Perovskites and corresponding changes in photoluminescence

International Nuclear Information System (INIS)

Sullivan, Eirin; Avdeev, Maxim; Vogt, Thomas

2012-01-01

The ordered oxyfluoride family Sr 3 − x A x MO 4 F (A=Ca, Ba and M=Al, Ga) has formed the basis of several new inorganic phosphors, and shows great potential for use in phosphor-conversion LED lamp devices. This study examines the correlation between subtle structural changes and photoluminescent behaviour in some of these materials. In order to ascertain whether cation charge compensation has any influence on structure and subsequent photoluminescent behaviour, a comparison was carried out between phases with the nominal compositions Sr 2.975 Ce 0.025 AlO 4 F and Sr 2.95 Ce 0.025 Na 0.025 AlO 4 F using structural characterisation based upon high-resolution neutron powder diffraction (NPD) data. Additionally, NPD data has been used to elucidate the role of different M cations in these materials, using Sr 2.25 Ba 0.6 Eu 0.1 M 0.95 In 0.05 O 4−α F 1−δ (M=Al, Ga) to determine the effect M cation size has on structure and photoluminescent properties. - Graphical abstract: The structure of Sr3-xAxMO4F (A=Ca, Ba and M=Al, Ga) and excitation and emission spectra for Sr 2.25 Ba 0.6 Eu 0.1 Ga 0.95 In 0.05 O 4−α F 1−δ . Highlights: ► Correlation between structural changes and photoluminescence in Sr 3−x A x MO 4 F (A=Ca, Ba, M=Al, Ga). ► Comparison of Sr 2.975 Ce 0.025 AlO 4 F and Sr 2.95 Ce 0.025 Na 0.025 AlO 4 F using high-resolution NPD. ► Study of the effect of cation charge-compensation on structure and photoluminescent behaviour. ► Examination of high-resolution NPD data for Sr 2.25 Ba 0.6 Eu 0.1 M 0.95 In 0.05 O 4−α F 1−δ (M=Al, Ga). ► Determination of the effect M cation size has on structure and photoluminescent properties.

Religion, coping and outcome in out-patients with depression or diabetes mellitus.

Science.gov (United States)

Amadi, K U; Uwakwe, R; Odinka, P C; Ndukuba, A C; Muomah, C R; Ohaeri, J U

2016-06-01

The study assesses the association between religiosity and coping style with the outcome of depression and diabetes. Using a simple random sampling, we recruited 112 participants with diabetes and an equal number with depression consecutively, matching for gender. Religiosity was determined using Religious Orientation Scale (revised) (ROS-R), coping styles with Brief Religious Coping (Brief RCOPE) scale and Mental Adjustment to Cancer (MAC) scale (adapted). Primary and secondary outcomes were evaluated using Sheehan's Disability Scale (SDS) and Becks Depression Inventory-II (BDI-II) respectively. Among participants with diabetes, BDI-II total scores correlated negatively with ROS-R Extrinsic Social (r = -0.2, P < 0.05) and Fighting Spirit (r = -0.3, P < 0.05) but correlated positively with Helplessness/Hopelessness (r = 0.3, P < 0.05) and Brief RCOPE Negative (r = 0.4, P < 0.05). SDS global scores correlated positively with Helplessness/Hopelessness (r = 0.3, P < 0.05) and Brief RCOPE Negative (r = 0.4, P < 0.05). Among participants with depression, BDI-II total scores correlated negatively with Intrinsic religiosity (r = -0.2, P < 0.05) and Fighting Spirit (r = -0.4, P < 0.05) but correlated positively with Helplessness/Hopelessness (r = 0.6, P < 0.05) and Brief RCOPE Negative (r = 0.7, P < 0.05). SDS global scores correlated negatively with Intrinsic religiosity (r = -0.2, P < 0.05) and Fighting Spirit (r = -0.3, P < 0.05) but correlated positively with Helplessness/Hopelessness (r = 0.5, P < 0.05) and Brief RCOPE Negative (r = 0.4, P < 0.05). High intrinsic and extrinsic religiosities are likely to be associated with positive coping skills and better treatment outcome in patients with depression or diabetes. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Genotype-Specific Regulation of Oral Innate Immunity by T2R38 Taste Receptor

Science.gov (United States)

Gil, Sucheol; Coldwell, Susan; Drury, Jeanie L.; Arroyo, Fabiola; Phi, Tran; Saadat, Sanaz; Kwong, Danny; Chung, Whasun Oh

2015-01-01

The bitter taste receptor T2R38 has been shown to regulate mucosal innate immune responses in the upper airway epithelium. Furthermore, SNPs in T2R38 influence the sensitivity to 6-n-propylthiouracil (PROP) and are associated with caries risk/protection. However, no study has been reported on the role of T2R38 in the innate immune responses to oral bacteria. We hypothesize that T2R38 regulates oral innate immunity and that this regulation is genotype-specific. Primary gingival epithelial cells carrying three common genotypes, PAV/PAV (PROP super-taster), AVI/PAV (intermediate) and AVI/AVI (non-taster) were stimulated with cariogenic bacteria Streptococcus mutans, periodontal pathogen Porphyromonas gingivalis or non-pathogen Fusobacterium nucleatum. QRT-PCR analyzed T2R38 mRNA, and T2R38-specific siRNA and ELISA were utilized to evaluate induction of hBD-2 (antimicrobial peptide), IL-1α and IL-8 in various donor-lines. Experiments were set up in duplicate and repeated three times. T2R38 mRNA induction in response to S. mutans was highest in PAV/PAV (4.3-fold above the unstimulated controls; p<0.05), while lowest in AVI/AVI (1.2-fold). In PAV/PAV, hBD-2 secretion in response to S. mutans was decreased by 77% when T2R38 was silenced. IL-1α secretion was higher in PAV/PAV compared to AVI/PAV or AVI/AVI with S. mutans stimulation, but it was reduced by half when T2R38 was silenced (p<0.05). In response to P. gingivalis, AVI/AVI showed 4.4-fold increase (p<0.05) in T2R38 expression, whereas the levels in PAV/PAV and AVI/PAV remained close to that of the controls. Secretion levels of IL-1α and IL-8 decreased in AVI/AVI in response to P. gingivalis when T2R38 was silenced (p<0.05), while the changes were not significant in PAV/PAV. Our data suggest that the regulation of gingival innate immunity by T2R38 is genotype-dependent and that the ability to induce a high level of hBD-2 by PAV/PAV carriers may be a reason for protection against caries in this group. PMID

CERN Technical Training 2005: MAGNE-05 - Magnétisme pour l’électrotechnique

CERN Multimedia

Davide Vitè

2005-01-01

Learning for the LHC ! Phénomènes magnétiques, matériaux et applications MAGNE-05 est un cours dans le cadre du programme de l’Enseignement Technique qui s’adresse aux personnes souhaitant découvrir, améliorer ou remettre à niveau leurs connaissances en magnétisme. Le cours est donné au CERN par la société CEDRAT Technologies basée à Meylan (France). La participation est ouverte à l’ensemble du personnel technique et scientifique nécessitant une formation en magnétisme dans le cadre de leurs activités professionnelles, courantes ou futures. Une importante économie par participant est réalisée par rapport aux frais nécessaires pour suivre la même formation sur le site de CEDRAT en France. MAGNE-05 s’intéresse, entre autres, au développement de la compréhension des phénomènes magnétiques et au « sens physique », appliqués à des produits industriels. Programme : Notions de base en électromagnétisme. Les aspects électrique et mécanique du magnétisme. Les régim...

CERN Technical Training 2005: MAGNE-05 - Magnétisme pour l'électrotechnique

CERN Multimedia

Davide Vitè

2005-01-01

Learning for the LHC ! Phénomènes magnétiques, matériaux et applications MAGNE-05 est un cours dans le cadre du programme de l'Enseignement technique qui s'adresse aux personnes souhaitant découvrir, améliorer ou remettre à niveau leurs connaissances en magnétisme. Le cours est donné au CERN par la société CEDRAT Technologies basée à Meylan (France). La participation est ouverte à l'ensemble du personnel technique et scientifique nécessitant une formation en magnétisme dans le cadre de leurs activités professionnelles, courantes ou futures. Une importante économie par participant est réalisée par rapport aux frais nécessaires pour suivre la même formation sur le site de CEDRAT en France. MAGNE-05 s'intéresse, entre autres, au développement de la compréhension des phénomènes magnétiques et au « sens physique », appliqués à des produits industriels. Programme : Notions de base en électromagnétisme. Les aspects électrique et mécanique du magnétisme. Les régimes variab...

CERN enseignement technique 2005: MAGNE-05 - Magnétisme pour l’électrotechnique

CERN Multimedia

Davide Vitè

2005-01-01

Learning for the LHC ! Phénomènes magnétiques, matériaux et applications MAGNE-05 est un cours dans le cadre du programme de l’Enseignement Technique qui s’adresse aux personnes souhaitant découvrir, améliorer ou remettre à niveau leurs connaissances en magnétisme. Le cours est donné au CERN par la société CEDRAT Technologies basée à Meylan (France). La participation est ouverte à l’ensemble du personnel technique et scientifique nécessitant une formation en magnétisme dans le cadre de leurs activités professionnelles, courantes ou futures. Une importante économie par participant est réalisée par rapport aux frais nécessaires pour suivre la même formation sur le site de CEDRAT en France. MAGNE-05 s’intéresse, entre autres, au développement de la compréhension des phénomènes magnétiques et au « sens physique », appliqués à des produits industriels. Programme : Notions de base en électromagnétisme. Les aspects électrique et mécanique du magnétisme. Les régi...

Phase formation, structure and dielectric properties of ceramics (Na0.5Bi0.5TiO3–(K0.5Na0.5NbO3–BiFeO3

Directory of Open Access Journals (Sweden)

G. M. Kaleva

2016-03-01

Full Text Available Influence of BiFeO3 (BF on phase formation, unit cell parameters, microstructure, dielectric and ferroelectric properties of solid solutions close to the morphotropic phase boundary in the (Na0.5Bi0.5TiO3–(K0.5Na0.5NbO3 system additionally modified by the low-melting KCl additives has been studied. The formation of pure perovskite structure samples decrease in the unit cell parameters and increase in the TC value stimulated by the BF addition have been revealed. It was proved that modification of compositions by small amounts of the BF and KCl additives leads to improvement of dielectric parameters.

Neutron diffraction and magnetic study of the Nd0.7Pb0.3Mn1-xFexO3 (0=

International Nuclear Information System (INIS)

Blanco, J.J.; Insausti, M.; Gil de Muro, I.; Lezama, L.; Rojo, T.

2006-01-01

The effect of Fe doping on the ferromagnetic Nd 0.7 Pb 0.3 Mn 1-x Fe x O 3 (x=0, 0.025, 0.05, 0.075, 0.1) phases has been studied in order to analyze the double-exchange interaction. The structural and magnetic study has been carried out by neutron powder diffraction and susceptibility measurements between 1.7 and 300K. The substitution of Fe at the Mn site results in reductions in both the Curie temperature T c and the magnetic moment per Mn ion without appreciable differences in the crystal structures. All the compounds crystallize in Pnma space group. The thermal evolution of the lattice parameters of the Nd 0.7 Pb 0.3 Mn 1-x Fe x O 3 (x=0.025, 0.05, 0.075) compounds shows discontinuities in volume and lattice parameters close to the magnetic transition temperature. Increasing amounts of Fe 3+ reduces the double exchange interactions and no magnetic contribution for x=0.1 is observed. The magnetic structures of Nd 0.7 Pb 0.3 Mn 1-x Fe x O 3 (x=0, 0.025, 0.05, 0.075) compounds show that the Nd and Mn ions are ferromagnetically ordered

Low-dose radiation-induced adaptive response in bone marrow cells of mice

International Nuclear Information System (INIS)

Farooqi, Zeba; Kesavan, P.C.

1993-01-01

Using bone marrow cells of whole body irradiated mice, the cytogenetic adaptive response induced by low conditioning doses of gamma-rays was investigated. The conditioning doses (0.025 and 0.05 Gy) were given at a dose-rate of 1.67 Gy/min. The challenging dose of 1 Gy was given at a dose-rate of 0.045 Gy/s. The challenging dose was given at different time intervals after the conditioning dose. The time intervals between the conditioning dose and challenging dose were 2, 7.5, 13, 18.5 and 24 h. When the time interval between the conditioning dose and the challenging dose was 2 h, both conditioning doses (0.025 and 0.05 Gy) reduced the frequency of MNPCEs and chromosomal aberrations in the bone marrow cells. The data collected at different time intervals (7.5, 13, 18.5 h) reveal that the radioadaptive response persisted for a longer time when the lower conditioning dose (0.025 Gy) was given. With the higher conditioning dose (0.05 Gy), the radioadaptive response disappeared after a time interval of 13 h. When the time interval between the conditioning dose and the challenging doses was 18.5 or 24 h, only the lower conditioning dose appeared effective in inducing the radioadaptive response

Molecular recognition of pyr mRNA by the Bacillus subtilis attenuation regulatory protein PyrR

Science.gov (United States)

Bonner, Eric R.; D’Elia, John N.; Billips, Benjamin K.; Switzer, Robert L.

2001-01-01

The pyrimidine nucleotide biosynthesis (pyr) operon in Bacillus subtilis is regulated by transcriptional attenuation. The PyrR protein binds in a uridine nucleotide-dependent manner to three attenuation sites at the 5′-end of pyr mRNA. PyrR binds an RNA-binding loop, allowing a terminator hairpin to form and repressing the downstream genes. The binding of PyrR to defined RNA molecules was characterized by a gel mobility shift assay. Titration indicated that PyrR binds RNA in an equimolar ratio. PyrR bound more tightly to the binding loops from the second (BL2 RNA) and third (BL3 RNA) attenuation sites than to the binding loop from the first (BL1 RNA) attenuation site. PyrR bound BL2 RNA 4–5-fold tighter in the presence of saturating UMP or UDP and 150- fold tighter with saturating UTP, suggesting that UTP is the more important co-regulator. The minimal RNA that bound tightly to PyrR was 28 nt long. Thirty-one structural variants of BL2 RNA were tested for PyrR binding affinity. Two highly conserved regions of the RNA, the terminal loop and top of the upper stem and a purine-rich internal bulge and the base pairs below it, were crucial for tight binding. Conserved elements of RNA secondary structure were also required for tight binding. PyrR protected conserved areas of the binding loop in hydroxyl radical footprinting experiments. PyrR likely recognizes conserved RNA sequences, but only if they are properly positioned in the correct secondary structure. PMID:11726695

Phylogeography of a widespread sub-Saharan murid rodent Aethomys chrysophilus: the role of geographic barriers and paleoclimate in the Zambezian bioregion

Czech Academy of Sciences Publication Activity Database

Mazoch, Vladimír; Mikula, Ondřej; Bryja, Josef; Konvičková, Hana; Russo, I.-R.; Verheyen, E.; Šumbera, R.

(2018) ISSN 0025-1461 R&D Projects: GA ČR GAP506/10/0983; GA ČR GA15-20229S Institutional support: RVO:68081766 Keywords : Aethomys chrysophilus * Aethomys ineptus * phylogeography * Plio-Pleistocene climate changes * Zambezian bioregion Subject RIV: EG - Zoology Impact factor: 0.805, year: 2016

Magnetoelectric effect of (1-x) Ba0.5Sr0.5Zr0.5Ti0.5O3+(x) Ni0.12Mg0.18Cu0.2Zn0.5Fe2O4 composites

Science.gov (United States)

Rahaman, Md. D.; Saha, S. K.; Ahmed, T. N.; Saha, D. K.; Hossain, A. K. M. Akther

2014-12-01

The magnetoelectric composites with chemical compositions (1-x) Ba0.5Sr0.5Zr0.5Ti0.5O3+(x) Ni0.12Mg0.18Cu0.2Zn0.5Fe2O4 (x=20, 40, 60 and 80 wt%) was prepared by the conventional solid state reaction method. The presence of a biphase composition was confirmed by X-ray diffraction while the microstructure of the composites was studied by scanning electron microscopy revealing a good mixing of the two phases and a good densification of the bulk ceramics. The dielectric dispersion is observed at lower frequencies due to interfacial polarization arising from the interface of the two phases. At higher frequencies, the dielectric constant is almost constant due to the inability of electric dipoles to follow the first variation of the alternating applied electric field. The dielectric loss shows maxima which are attributed when the hopping frequency of electrons between different ionic sites becomes nearly equal to the frequency of the applied field. The linearity in the log(σAC) vs. log(ω2) plots confirmed the small polaron hopping type of conduction mechanism. The composite materials are found to exhibit an excellent frequency dependence of magnetic properties. In the high frequency range, with increasing ferrite concentration the initial permeability increases and cut-off frequency decreases. An optimal magnetoelectric coupling responding voltage of about 600 μV cm-1 Oe-1 is obtained for x=20 wt% at room temperature.

33 CFR 5.05 - Organization.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Organization. 5.05 Section 5.05 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY GENERAL COAST GUARD AUXILIARY § 5.05 Organization. The Auxiliary is a nonmilitary organization administered by the Commandant, under...

Crystal and magnetic study of the disordered perovskites Ca(Mn{sub 0.5}Sb{sub 0.5})O{sub 3} and Ca(Fe{sub 0.5}Sb{sub 0.5})O{sub 3}

Energy Technology Data Exchange (ETDEWEB)

Retuerto, M., E-mail: mretuerto@icmm.csic.es [Instituto de Ciencia de Materiales de Madrid, CSIC, Energia, Medio Ambiente y Tecnologias Sostenibles, Sor Juana Ines de la Cruz 3, Cantoblanco, E-28049 Madrid (Spain); Martinez-Lope, M.J.; Garcia-Hernandez, M. [Instituto de Ciencia de Materiales de Madrid, CSIC, Energia, Medio Ambiente y Tecnologias Sostenibles, Sor Juana Ines de la Cruz 3, Cantoblanco, E-28049 Madrid (Spain); Munoz, A. [Departamento de Fisica Aplicada, EPS, Universidad Carlos III, Avda. Universidad 30, E-28911 Leganes-Madrid (Spain); Fernandez-Diaz, M.T. [Institut Max Von Laue Paul Langevin, F-38042 Grenoble (France); Alonso, J.A. [Instituto de Ciencia de Materiales de Madrid, CSIC, Energia, Medio Ambiente y Tecnologias Sostenibles, Sor Juana Ines de la Cruz 3, Cantoblanco, E-28049 Madrid (Spain)

2010-10-15

We have investigated the double perovskites Ca{sub 2}MSbO{sub 6} (M = Mn, Fe) that have been prepared by solid-state reaction (M = Fe) and wet chemistry procedures (M = Mn). The crystal and magnetic structures have been studied from X-ray (XRD) and neutron powder diffraction (NPD) data. Rietveld refinements show that the crystal structures are orthorhombic (space group Pbnm) with complete disorder of M and Sb cations, so the formula should be rewritten as Ca(M{sub 0.5}Sb{sub 0.5})O{sub 3}. Due to this disorder no evidences of Jahn-Teller distortion can be observed in the MnO{sub 6} octahedra of Ca(Mn{sub 0.5}Sb{sub 0.5})O{sub 3}, in contrast with the ordered double perovskite Sr{sub 2}MnSbO{sub 6}. Ca(Fe{sub 0.5}Sb{sub 0.5})O{sub 3} behaves as an antiferromagnet with an ordered magnetic moment for Fe{sup 3+} of 1.53(4){mu}{sub B} and a propagation vector k = 0, as investigated by low-temperature NPD. The antiferromagnetic ordering is a result of the high degree of Fe/Sb anti-site disorder of the sample, which originates the spontaneous formation of Fe-rich islands, characterized by the presence of strong Fe-O-Fe antiferromagnetic couplings with enough long-range coherence to produce a magnetic contribution perceptible by NPD. By contrast, the magnetic structure of Ca(Mn{sub 0.5}Sb{sub 0.5})O{sub 3} cannot be observed by low-temperature NPD because the magnitude of the ordered magnetic moments is below the detection threshold for neutrons.

Effects of a triphasic combination oral contraceptive containing norgestimate/ethinyl estradiol on biochemical markers of bone metabolism in young women with osteopenia secondary to hypothalamic amenorrhea.

Science.gov (United States)

Grinspoon, S K; Friedman, A J; Miller, K K; Lippman, J; Olson, W H; Warren, M P

2003-08-01

This multicenter, double-blind, placebo-controlled, randomized study of 45 patients evaluated the short-term effects of an oral contraceptive [Ortho Tri-Cyclen, 180-250 micro g of norgestimate (NGM) and 35 microg of ethinyl estradiol (EE)] on biochemical markers of bone resorption, formation, and osteoprotegerin in young women (mean age +/- SD, 26.5 +/- 6.3 yr) with hypothalamic amenorrhea and osteopenia. Body fat, endocrine, and cognitive function were evaluated as secondary endpoints. Biomarkers of bone metabolism were measured at baseline and after three cycles of NGM/EE or placebo. There were significant decreases in mean values of N-telopeptide [mean (SD), -13.4 (13.4) vs. 1.2 (23.8) nmol bone collagen equivalents (BCE)/mmol creatinine (Cr); P = 0.001] and deoxypyridinoline [-1.2 (2.9) vs. -0.5 (1.5) nmol deoxypyridinoline/mmol Cr; P = 0.021] as well as significant decreases in bone specific alkaline phosphatase [-5.1 (3.5) vs. 0.4 (3.1) ng/ml; P < 0.001], osteocalcin [-5.9 (3.6) vs. -2.9 (3.7); P = 0.016], and procollagen of type I propeptide [-35.2 (44.6) vs. -0.2 (30.0) ng/ml; P = 0.025], but not osteoprotegerin [0.39 (1.46) vs. -0.2 (0.49) pmol/liter; P = 0.397] in the NGM/EE vs. placebo group. There were no significant differences between groups with respect to changes in cognitive function, mood, body weight, body mass index, body fat, percentage of body fat, and all endocrine levels except FSH, [-3.7 (3.8) vs. -0.6 (2.1) IU/liter; P < 0.001, NGM/EE vs. placebo]. No serious adverse events were reported in either group. These results suggest that NGM/EE decreases bone turnover in osteopenic premenopausal women with hypothalamic amenorrhea. Further studies are needed to determine whether estrogen will increase bone density in this population.

Is heat pain detection threshold associated with the area of secondary hyperalgesia following brief thermal sensitization? A study of healthy volunteers - design and detailed plan of analysis.

Science.gov (United States)

Hansen, Morten Sejer; Wetterslev, Jørn; Pipper, Christian Bressen; Asghar, Mohammad Sohail; Dahl, Jørgen Berg

2016-05-31

Several factors are believed to influence the development and experience of pain. Human clinical pain models are central tools, in the investigation of basic physiologic pain responses, and can be applied in patients as well as in healthy volunteers. Each clinical pain model investigates different aspects of the human pain response. Brief thermal sensitization induces a mild burn injury, resulting in development of primary hyperalgesia at the site of stimulation, and secondary hyperalgesia surrounding the site of stimulation. Central sensitization is believed to play an important role in the development of secondary hyperalgesia; however, a possible association of secondary hyperalgesia following brief thermal sensitization and other heat pain models remains unknown. Our aim with this study is to investigate how close the heat pain detection threshold is associated with the size of the area of secondary hyperalgesia induced by the clinical heat pain model: Brief thermal sensitization. We aim to include 120 healthy participants. The participants will be tested on two separate study days with the following procedures: i) Brief thermal sensitization, ii) heat pain detection threshold and iii) pain during thermal stimulation. Additionally, the participants will be tested with the Pain Catastrophizing Scale and Hospital Anxiety and Depression Scale questionnaires. We conducted statistical simulations based on data from our previous study, to estimate an empirical power of 99.9 % with α of 0.05. We define that an R(2) heat stimulation, and thus may be a biomarker of an individual's pain sensitivity. The number of studies investigating secondary hyperalgesia is growing; however basic knowledge of the physiologic aspects of secondary hyperalgesia in humans is still incomplete. We therefore find it interesting to investigate if HPDT, a known quantitative sensory test, is associated with areas of secondary hyperalgesia following brief thermal sensitization Clinicaltrials

Synthesis and characterization of BaTi1−xSnxO3–0.5 mol%GeO2

International Nuclear Information System (INIS)

Bucur, Raul Alin; Bucur, Alexandra Ioana; Novaconi, Stefan; Nicoara, Irina

2012-01-01

Highlights: ► BaTi 1−x Sn x O 3 –0.5 mol%GeO 2 (x = 0, 0.1, 0.3, 0.5) ceramics were prepared at 1190 °C. ► GeO 2 improves crystallization and densification. ► Anomalies are noted for the rhombohedral–orthorhombic transition of BT–0.5Ge. ► For x = 0.3 and 0.5, ε′ r exhibit nearly constant variation between 200 and 400 K. - Abstract: Microcrystalline BaTi 1−x Sn x O 3 –0.5 mol%GeO 2 x = 0, 0.1, 0.3, 0.5 (BTSx–0.5Ge) and BaTiO 3 (BT) ceramics (1–0.5 μm) were prepared by a conventional solid-state reaction method. The crystalline structure of the samples was examined using XRD, the microstructure was analyzed by means of electron microscope and the density was measured by the Archimede’s method. The sintered ceramic disks have a tetragonal symmetry for BT, pseudo cubic for BTS1–0.5Ge and cubic symmetry for the other studied materials, with a gradual increase of unit cell dimensions. Small addition of GeO 2 can improve the density of BT ceramics: 97.9% for BT–0.5Ge, and 96.21% for pure BT. The highest degree of densification in the case of tin doping is achieved for BTS1–0.5Ge (96.93%). The formation of a liquid phase can lead to an anomalous grain growth, and in the case of BT–0.5Ge the grains are completely surrounded by a frozen eutectic melt. For the dielectric constant, while increasing the Sn concentration, the T C gradually shifts towards lower temperatures, and the peak of this transition becomes broader. The lowering of T C is mostly due to the concentration of tin ions and in a much delicate way to Ge ions. Anomalies are noticed for the orthorhombic transition, where the permittivity is higher than the same transition of the matrix (BT), with a shift towards higher temperatures. The BTS3–0.5Ge and BTS5–0.5Ge are the most stable compositions in terms of dielectric behavior, since in the temperature range 200–400 K, ε′ r is almost constant. Therefore, these compositions can be used for devices that operate over a

Stratus Ocean Reference Station (20 deg. S, 85 deg. W) : Mooring Recovery and Deployment Cruise, R/V Ronald H. Brown Cruise 05-05, September 26, 2005-October 21, 2005

National Research Council Canada - National Science Library

Hutto, Lara; Weller, Robert; Lord, Jeff; Smith, Jason; Bouchard, Paul; Fairall, Chris; Pezoa, Sergio; Bariteau, Ludovic; Lundquist, Jessica; Ghate, Virendra

2006-01-01

.... During the October 2005 cruise of NOAA's R/V Ronald H. Brown to the ORS Stratus site, the primary activities were recovery of the WHOl surface mooring that had been deployed in December 2004, deployment of a new...

X-ray photoelectron spectroscopic study of direct reforming catalysts Ln{sub 0.5}Sr{sub 0.5}Ti{sub 0.5}Mn{sub 0.5}O{sub 3±d} (Ln = La, Nd, and Sm) for high temperature-operating solid oxide fuel cell

Energy Technology Data Exchange (ETDEWEB)

Kim, Keunsoo [Department of Engine Research, Korea Institute of Machinery and Materials, 156 Gajeongbuk-Ro, Daejeon 305-343 (Korea, Republic of); Jeong, Jihoon [Department of Mechanical Engineering, The University of Texas at Austin, Austin, TX 78712 (United States); Azad, Abul K. [Faculty of Integrated Technologies, University Brunei Darussalam, Jalan Tunku Link, Gadong BE1410 (Brunei Darussalam); Jin, Sang Beom [Department of Advanced Materials Science and Engineering, Hanbat National University, 125, Dongseo-Daero, Yusung-Gu, Daejeon 305-719 (Korea, Republic of); Kim, Jung Hyun, E-mail: jhkim2011@hanbat.ac.kr [Department of Advanced Materials Science and Engineering, Hanbat National University, 125, Dongseo-Daero, Yusung-Gu, Daejeon 305-719 (Korea, Republic of)

2016-03-01

Graphical abstract: Measured Ti 2p peaks and deconvolution peaks of Nd{sub 0.5}Sr{sub 0.5}Ti{sub 0.5}Mn{sub 0.5}O{sub 3±d} under oxidizing condition (left) and NSTM under reducing condition (right). - Highlights: • Chemical states of Ln{sub 0.5}Sr{sub 0.5}Ti{sub 0.5}Mn{sub 0.5}O{sub 3±d} (Ln: La, Nd and Sm) were analyzed. • Charge compensation occurred with the reduction of Mn and Ti. • The Nd substitution effect allowed some Ti to convert into a metallic behavioral component. • NSTM and SSTM had a large amount of lattice oxygen; however, LSTM retained a large quantity of adsorbed oxygen. - Abstract: Chemical states of lanthanide doped perovskite for direct reforming anode catalysts, Ln{sub 0.5}Sr{sub 0.5}Ti{sub 0.5}Mn{sub 0.5}O{sub 3±d} (Ln = La, Nd, and Sm) have been studied by X-ray Photoelectron Spectroscopy (XPS) in order to determine the effects of various lanthanide substitution in complex perovskites for high temperature-operating solid oxide fuel cells (HT-SOFC). The charge state of lanthanide ions remained at 3+ and the binding energies of the lanthanide ions in Ln{sub 0.5}Sr{sub 0.5}Ti{sub 0.5}Mn{sub 0.5}O{sub 3±d} were located in a relatively lower range compared to those of conventional lanthanide oxides. Mn and Ti were regarded as charge compensation components in Ln{sub 0.5}Sr{sub 0.5}Ti{sub 0.5}Mn{sub 0.5}O{sub 3±d}; Mn was more influential than Ti. In the cases of substituting Nd and Sm into Ln{sub 0.5}Sr{sub 0.5}Ti{sub 0.5}Mn{sub 0.5}O{sub 3±d}, some portion of Ti showed metallic behavior; the specific Mn satellite peak indicating an electro-catalytic effect had occurred. Three types of oxygen species comprised of lattice oxygen, carbonate species, and adsorbed oxygen species were observed in Ln{sub 0.5}Sr{sub 0.5}Ti{sub 0.5}Mn{sub 0.5}O{sub 3±d} from the O 1s spectra; a high portion of lattice oxygen was observed in both Nd{sub 0.5}Sr{sub 0.5}Ti{sub 0.5}Mn{sub 0.5}O{sub 3±d} (NSTM) and Sm{sub 0.5}Sr{sub 0.5}Ti{sub 0.5}Mn{sub 0.5}O

21 CFR 1310.05 - Reports.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Reports. 1310.05 Section 1310.05 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE RECORDS AND REPORTS OF LISTED CHEMICALS AND CERTAIN MACHINES § 1310.05 Reports. (a) Each regulated person shall report to the Special Agent in Charge...

Dielectric and Ferroelectric Properties of SrTiO3-Bi0.5Na0.5TiO3-BaAl0.5Nb0.5O3 Lead-Free Ceramics for High-Energy-Storage Applications.

Science.gov (United States)

Yan, Fei; Yang, Haibo; Lin, Ying; Wang, Tong

2017-11-06

Pulsed capacitors require high-recoverable energy-storage density (W rec ) and high energy-storage efficiency (η), which can be realized through the selection and adjustment of the composition. In this work, (1 - x)SrTiO 3 -x(0.95Bi 0.5 Na 0.5 TiO 3 -0.05BaAl 0.5 Nb 0.5 O 3 ) [(1 - x)ST-x(BNT-BAN)] ceramics were successfully prepared via the pressureless solid-state reaction method. The dielectric constant increases gradually with the introduction of BNT-BAN and obtains a maximum value of 3430 with the composition of 0.4ST-0.6(BNT-BAN) at 100 Hz, which is 10.39 times higher than that of the pure ST sample (∼330). Dispersive relaxor behaviors and ferroelectric performances can be enhanced with the introduction of BNT-BAN. The composition of 0.5ST-0.5(BNT-BAN) exhibits a high W rec of 1.89 J/cm 3 as well as a high η of 77%. Therefore, the (1 - x)ST-x(BNT-BAN) systems are candidate materials for pulsed capacitor applications.

Dielectric and piezoelectric properties of BiFeO3 modified Bi0.5Na0.5TiO3-Bi0.5K0.5TiO3 lead-free piezoelectric ceramics

International Nuclear Information System (INIS)

Zhou Changrong; Liu Xinyu; Li Weizhou

2008-01-01

The (0.82 - x)Bi 0.5 Na 0.5 TiO 3 -0.18Bi 0.5 K 0.5 TiO 3 -xBiFeO 3 (x = 0-0.07) lead-free piezoelectric ceramics were fabricated by a conventional solid-state reaction method and the effect of BiFeO 3 addition on microstructure and electrical properties of the ceramics was investigated. The specimens with x ≤ 0.05 maintained a rhombohedral-tetragonal phase coexistence and changed into a rhombohedral phase when x > 0.05 in crystal structure. The addition of BiFeO 3 caused a promoted grain growth. All the specimens reveal a low-frequency dielectric dispersion in the frequency range of 40-1 MHz. The piezoelectric constant d 33 and the electromechanical coupling factor k p show an obvious improvement by the addition of small amount of BiFeO 3 , which shows optimum values of d 33 = 170 pC/N and k p = 0.366 at x = 0.03. Contrary to the enhancement of piezoelectric properties, Q m decreases with increasing BiFeO 3 content. The mechanisms of intrinsic and extrinsic contributions to the dielectric and piezoelectric responses have been proposed. Intrinsic contributions are from the relative ion/cation shift that preserves the ferroelectric crystal structure. The remaining extrinsic contributions are from the domain-wall motion and point defects

Flow boiling heat transfer and pressure drop characteristics of R134a, R1234yf and R1234ze in a plate heat exchanger for organic Rankine cycle units

DEFF Research Database (Denmark)

Zhang, Ji; Desideri, Adriano; Kærn, Martin Ryhl

2017-01-01

. This paper is aimed at obtaining flow boiling heat transfer and pressure drop characteristics in a plate heat exchanger under the working conditions prevailing in the evaporator of organic Rankine cycle units. Two hydrofluoroolefins R1234yf and R1234ze, and one hydrofluorocarbon R134a, were selected...... as the working fluids. The heat transfer coefficients and pressure drops of the three working fluids were measured with varying saturation temperatures, mass fluxes, heat fluxes and outlet vapour qualities, which range from 60°C to 80°C, 86 kg/m2 s to 137 kg/m2 s, 9.8 kW/m2 to 36.8 kW/m2 and 0.5 to 1...... developed that are more suitable for evaporation in organic Rankine cycles. The experimental results indicate that heat transfer coefficients are strongly dependent upon the heat flux and saturation temperature. Moreover, the results suggest better thermal-hydraulic performance for R1234yf than the other...

Friction between various self-ligating brackets and archwire couples during sliding mechanics.

Science.gov (United States)

Stefanos, Sennay; Secchi, Antonino G; Coby, Guy; Tanna, Nipul; Mante, Francis K

2010-10-01

The aim of this study was to evaluate the frictional resistance between active and passive self-ligating brackets and 0.019 × 0.025-in stainless steel archwire during sliding mechanics by using an orthodontic sliding simulation device. Maxillary right first premolar active self-ligating brackets In-Ovation R, In-Ovation C (both, GAC International, Bohemia, NY), and SPEED (Strite Industries, Cambridge, Ontario, Canada), and passive self-ligating brackets SmartClip (3M Unitek, Monrovia, Calif), Synergy R (Rocky Mountain Orthodontics, Denver, Colo), and Damon 3mx (Ormco, Orange, Calif) with 0.022-in slots were used. Frictional force was measured by using an orthodontic sliding simulation device attached to a universal testing machine. Each bracket-archwire combination was tested 30 times at 0° angulation relative to the sliding direction. Statistical comparisons were performed with 1-way analysis of variance (ANOVA) followed by Dunn multiple comparisons. The level of statistical significance was set at P <0.05. The Damon 3mx brackets had significantly the lowest mean static frictional force (8.6 g). The highest mean static frictional force was shown by the SPEED brackets (83.1 g). The other brackets were ranked as follows, from highest to lowest, In-Ovation R, In-Ovation C, SmartClip, and Synergy R. The mean static frictional forces were all statistically different. The ranking of the kinetic frictional forces of bracket-archwire combinations was the same as that for static frictional forces. All bracket-archwire combinations showed significantly different kinetic frictional forces except SmartClip and In-Ovation C, which were not significantly different from each other. Passive self-ligating brackets have lower static and kinetic frictional resistance than do active self-ligating brackets with 0.019 × 0.025-in stainless steel wire. Copyright © 2010 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

Near-Infrared Mapping Spectrometer for investigation of Jupiter and its satellites

International Nuclear Information System (INIS)

Aptaker, I.M.

1988-01-01

The Near-Infrared-Mapping Spectrometer (NIMS) is one of the science instruments in the Galileo mission, which will explore Jupiter and its satellites in the mid-1990's. The NIMS experiment will map geological units on the surfaces of the Jovian satellites and characterize their mineral content; and, for the atmosphere of Jupiter, investigate cloud properties and the spatial and temporal variability of molecular abundances. The optics are gold-coated reflective and consist of a telescope and a grating spectrometer. The balance of the instrument includes a 17-detector (silicon and indium antimonide) focal plane array, a tuning fork chopper, microprocessor-controlled electronics, and a passive radiative cooler. A wobbling secondary mirror in the telescope provides 20 pixels in one dimension of spatial scanning in a pushbroom mode with 0.5 mr x 0.5 mr instantaneous field of view. The spectral range is 0.7-5.2 microns; resolution is 0.025 micron. NIMS is the first infrared experiment to combine both spatial and spectral mapping capability in one instrument

The Interaction of Selective Attention and Cognitive Development on Achievement in Nigerian Secondary School Genetics

Science.gov (United States)

Okoye, Namdi N. S.

2009-01-01

The study tried to examine the interaction between two independent variables of selective attention and cognitive development on Achievement in Genetics at the Secondary School level. In looking at the problem of this study three null hypotheses were generated for testing at 0.05 level of significance. Factorial Analysis of Variance design with…

Multiaxial creep of fine grained 0.5Cr-0.5Mo-0.25V and coarse grained 1Cr-0.5Mo steels

International Nuclear Information System (INIS)

Browne, R.J.; Flewitt, P.E.J.; Lonsdale, D.

1991-01-01

To explore the multiaxial creep response of materials used for electrical power generating plant, two steels, a fine grained 0.5Cr-0.5Mo-0.25V steel in a normalised and tempered condition with high creep ductility and a coarse grained 1Cr-0.5Mo steel in a quenched and tempered condition with low uniaxial creep ductility, have been selected. A range of multiaxial stress testing techniques which span the stress states that would allow identification of any technique dependent variables has been used. The deformation and failure of the normalised and tempered 0.5Cr-0.5Mo-0.25V steel for a range of multiaxial test techniques and, therefore, stress states may be described by an equivalent stress criterion. The results from the multiaxial tests carried out on the fully bainitic 1Cr-0.5Mo steel show that the multiaxial stress rupture criterion (MSRC) varies with stress state; at high triaxiality (notch), it is controlled by the maximum principal stress, whereas at low triaxiality (shear) it is dependent on both maximum principal stress and equivalent stress. Furthermore, a simple description of stress state based on maximum principal and equivalent stress does not define this uniquely, since the MSRC derived from uniaxial and torsion testing does not describe the failure of notch, tube, or double shear tests. (author)

S-05: Düzenli Fiziksel Aktivitenin Dikkat Eksikliği ve Hiperaktivite Bozukluğu Olan Çocuklardaki Etkisinin Araştırılması

Directory of Open Access Journals (Sweden)

Abdülaziz Türksoylu

2017-03-01

Full Text Available AMAÇ: Düzenli fiziksel aktivitenin 8-12 yaş arası Dikkat Eksikliği ve Hiperaktivite Bozukluğu (DEHB tanısı alan ve en az 6 ay stimülan tedavi kullanan çocuklar üzerindeki etkisinin araştırılması amaçlanmıştır.YÖNTEM: Randomize kontrollü olarak planlanan çalışmaya DEHB tanısı alan, 8-12 yaş arası, 46 erkek çocuk dahil edildi. 23 olgu kontrol grubu, diğer 23 olgu ise düzenli fiziksel aktivite (DFA grubu olmak üzere randomize edildi. Tüm olgulara DuPaul DEHB Değerlendirme Ölçeği, Çocuk için Yaşam Kalitesi Ölçeği (ÇİYKÖ 8-12 yaş grubu Ebeveyn ve Çocuk Formu ve Güçler Güçlükler Anketi (GGA uygulandı. Kontrol grubu 10 hafta boyunca mevcut stimülan tedaviyi almaya devam etti ve herhangi bir ek müdahale yapılmadı. DFA grubuna ise en az 60 dakika süren futbol antrenmanı, haftada 3 gün, 10 hafta boyunca yaptırıldı. DFA grubunda, izlemde 19 olgu düzenli fiziksel aktiviteye devam edebilmiş ve çalışmayı tamamlamıştır. 10 hafta sonunda tüm olgulara DuPaul DEHB Değerlendirme Ölçeği, ÇİYKÖ 8-12 yaş grubu Ebeveyn ve Çocuk Formu ve GGA tekrar uygulandı.BULGULAR: Çalışmamızda DFA grubu ve kontrol grubu yaş ortalamaları, DEHB alt tipleri ve Komorbidite dağılımları birbirine benzerdi. DFA grubunun fiziksel aktivite öncesi ve sonrası testleri karşılaştırıldığında; GGA alt ölçeklerinde duygusal, davranış, dikkat eksikliği ve aşırı hareketlilik, akran ilişkileri ve toplam güçlük puanlarında anlamlı azalma (p0,05.SONUÇ: Çalışma sonuçları, düzenli fiziksel aktivitenin stimülan tedavi alan DEHB tanısı olan çocukların DEHB belirtilerini, hastalığın şiddetini ve davranışsal sorunlarını azalttığını, çocukların yaşam kalitesi üzerine olumlu etkileri olduğunu göstermektedir. DEHB olan çocuklarda, stimülan tedaviye ek olarak düzenli fiziksel aktivitenin yapılması iyileşmeye katkıda bulunabilir.

R and D LMFRs knowledge preservation French project

International Nuclear Information System (INIS)

Baque, F.

2004-01-01

The French Institutions involved in LMFRs development (EDF Utilities, CEA Research Institute and FRAMATOME-ANP Engineering) decided in 2000 year to preserve the R and D knowledge which was raised during the last four decades of the 20th century: the long term availability (some decades) of LMFRs experience should be maintained thanks to an extensive, everlasting and intelligible form which could allow future designers to use this great amount of knowledge. Among different types of architecture, the LMFRs Fund of Knowledge is being raised in 2001 and 2002 along two complementary ways: - The main one gives an overall vision of R and D work undertaken through 23 R and D items: an overall view of LMFRs conception; 9 items about Core R and D work (Safety, Working, Thermohydraulics, Thermomechanics, Design Rules, Materials, Fuel clad failure, Neutronics, Nuclear fuel; 13 items about Reactor R and D work (Safety, Working, Sodium Coolant, Sodium Technology, Thermohydraulics, cover gas Aerolics, Thermomechanics, Design Rules, in sodium equipment Mechanics, Materials, In Service Inspection and Repair, Sodium Fires, Decommissioning). - The other one deals with the Design of what can be a LMFR: Superphenix Plant was chosen as the largest and validated industrial size LMFR through the conception of its 41 systems (Core system, Monitoring systems, Protective and Shut-down systems, Primary systems, Secondary and Steam Generator Systems, Decay Heat Removal system, Primary and secondary Handling systems, Cleaning and Decontamination systems, Fuel Storage system). Each R and D item and each Superphenix system is described with a Documentary Form, written by French specialist: after a brief description of the different sub-items (some pages), the list of relevant references are listed (some dozens to some hundreds of synthesis reports, basic literature, specialist interviews, Superphenix measurement data, EFR Project synthesis). Thus, the LMFRs Fund of Knowledge is made of the 64

Structire ordering effect on dielectric properties of PbInsub(0.5)Nbsub(0.5)Osub(3) crystals

International Nuclear Information System (INIS)

Turik, A.V.; Kupriyanov, M.F.; Zhestkov, B.F.

1985-01-01

Results are presented of dielectric and X-ray diffraction investigations into the PbZnsub(0.5)Nbsub(0.5)Osub(3) monocrystals of PbBsub(0.5)'Bsub(0.5)''Osub(3) series (B'=ScIn, B''=Nb, Ta) annealed during 5 hours at 500 deg C. It is shown that ordering in the B'-cation position in crystals influences the character of alternation of phases and physical properties. The PbInsub(0.5)Nbsub(0.5)Osub(3) crystals may be either in rhombohedral ferro- or zhombic antiferroelectric phases depending on thermal prehistory

2018-05-08T22:00:46Z https://www.ajol.info/index.php/all/oai oai:ojs ...

African Journals Online (AJOL)

article/63977 2018-05-08T22:00:46Z ijmu:ART Cancer Epigenomics: a review Kumar, R Sharan, N Cancer; Epigenomics; Methylation Epigenetic inactivation of genes that are crucial for the control of normalcell growth is a hallmark of cancer cells.

Electronic transport and magnetoresistivity of La0.4Bi0.1Ca0.5 ...

Indian Academy of Sciences (India)

Administrator

for their intriguing electric and magnetic properties.1 One of the interesting ... ground state is sensitive to the average size 〈rA〉 of A-site cation (La3+ .... (~ 300 nm in diameter) are nearly spherical in shape and uniform in ... Figure 3. Temperature-dependent resistivity of La0.4Bi0.1. Ca0.5–xSrxMnO3 (x = 0.1 and 0.2). transition ...

Structure-property correlation in PrFe0.5Mn0.5O2.95

International Nuclear Information System (INIS)

Ganeshraj, C.; Santhosh, P.N.; Sharma, Neetika; Das, A.; Mahendiran, R.

2014-01-01

PrFe 0.5 Mn 0.5 O 2.95 (PFMO) prepared by the conventional ceramic route is analyzed using a variety of techniques to understand the structural, magnetic and electrical properties. From the Neutron diffraction data it is concluded that PFMO crystallizes in an orthorhombic structure (Pnma). The magnetic structure can be represented as Γ 2 : C x G y F z , in Bertaut's notation, which has a net ferromagnetic moment along z-direction, and the spin component along x-direction (C x ) is found to be negligibly small. The canted G-type antiferromagnet PrFe 0.5 Mn 0.5 O 2.95 shows an enhanced Jahn-Teller (JT) distortion below 150 K (T*). The resistivity of the grains can be described by variable range hopping (VRH) between the localized states and there is a dominant grain boundary contribution to dc resistivity, below T*. Above T*, the total dc resistivity follows small polaron hopping (SPH) conduction. By means of complex impedance analysis, it is found that the observed giant dielectric response can be ascribed to Maxwell-Wagner polarization at the grain/grain boundary interfaces. Despite the low concentration of JT active Mn 3+ ions, our result indicates an important role of JT effect on physical properties of PrFe 0.5 Mn 0.5 O 2.95 . (author)

The secondary release of mercury in coal fly ash-based flue-gas mercury removal technology.

Science.gov (United States)

He, Jingfeng; Duan, Chenlong; Lei, Mingzhe; Zhu, Xuemei

2016-01-01

The secondary release of mercury from coal fly ash is a negative by-product from coal-fired power plants, and requires effective control to reduce environmental pollution. Analysing particle size distribution and composition of the coal fly ash produced by different mercury removing technologies indicates that the particles are generally less than 0.5 mm in size and are composed mainly of SiO2, Al2O3, and Fe2O3. The relationships between mercury concentration in the coal fly ash, its particle size, and loss of ignition were studied using different mercury removing approaches. The research indicates that the coal fly ash's mercury levels are significantly higher after injecting activated carbon or brominating activated carbon when compared to regular cooperating-pollution control technology. This is particularly true for particle size ranges of >0.125, 0.075-0.125, and 0.05-0.075 mm. Leaching experiments revealed the secondary release of mercury in discarded coal fly ash. The concentration of mercury in the coal fly ash increases as the quantity of injecting activated carbon or brominating activated carbon increases. The leached concentrations of mercury increase as the particle size of the coal fly ash increases. Therefore, the secondary release of mercury can be controlled by adding suitable activated carbon or brominating activated carbon when disposing of coal fly ash. Adding CaBr2 before coal combustion in the boiler also helps control the secondary release of mercury, by increasing the Hg(2+) concentration in the leachate. This work provides a theoretical foundation for controlling and removing mercury in coal fly ash disposal.

Swift BAT Thermal Recovery After Loop Heat Pipe #0 Secondary Heater Controller Failure in October 2015

Science.gov (United States)

Choi, Michael K.

2016-01-01

The Swift BAT LHP #0 primary heater controller failed on March 31, 2010. It has been disabled. On October 31, 2015, the secondary heater controller of this LHP failed. On November 1, 2015, the LHP #0 CC temperature increased to as 18.6 C, despite that the secondary heater controller set point was 8.8 C. It caused the average DM XA1 temperature to increase to 25.9 C, which was 5 C warmer than nominal. As a result, the detectors became noisy. To solve this problem, the LHP #1 secondary heater controller set point was decreased in 0.5 C decrements to 2.2 C. The set-point decrease restored the average DM XA1 temperature to a nominal value of 19.7 C on November 21.

Comparative efficacy and safety of approved treatments for macular oedema secondary to branch retinal vein occlusion

DEFF Research Database (Denmark)

Regnier, Stephane A; Larsen, Michael; Bezlyak, Vladimir

2015-01-01

OBJECTIVE: To compare the efficacy and safety of approved treatments for macular oedema secondary to branch retinal vein occlusion (BRVO). DESIGN: Randomised controlled trials (RCTs) evaluating the efficacy and safety of approved treatments for macular oedema secondary to BRVO were identified from...... an updated systematic review. SETTING: A Bayesian network meta-analysis of RCTs of treatments for macular oedema secondary to BRVO. INTERVENTIONS: Ranibizumab 0.5 mg pro re nata, aflibercept 2 mg monthly (2q4), dexamethasone 0.7 mg implant, laser photocoagulation, ranibizumab+laser, or sham intervention...... pressure (IOP)/ocular hypertension (OH). RESULTS: 8 RCTs were identified for inclusion with 1743 adult patients. The probability of being the most efficacious treatment at month 6 or 12 based on letters gained was 54% for ranibizumab monotherapy, 30% for aflibercept, 16% for ranibizumab plus laser...

Ectopic Overexpression of a Novel R2R3-MYB, NtMYB2 from Chinese Narcissus Represses Anthocyanin Biosynthesis in Tobacco

Directory of Open Access Journals (Sweden)

Muhammad Anwar

2018-03-01

Full Text Available R2R3 MYB transcription factors play key functions in the regulation of secondary metabolites. In the present study, a R2R3 MYB transcriptional factor NtMYB2 was identified from Chinese narcissus (Narcissus tazetta L. var. Chinensis Roem and functionally characterized. NtMYB2 belongs to subgroup 4 of the R2R3 MYB transcription factor family that are related to repressor MYBs involved in the regulation of anthocyanin and flavonoids. Transient expression confirmed that NtMYB2 strongly reduced the red pigmentation induced by MYB- anthocyanin activators in agro-infiltrated tobacco leaves. Ectopic expression of NtMYB2 in tobacco significantly reduced the pigmentation and altered the floral phenotypes in transgenic tobacco flowers. Gene expression analysis suggested that NtMYB2 repressed the transcript levels of structural genes involved in anthocyanin biosynthesis pathway, especially the UFGT gene. NtMYB2 gene is expressed in all examined narcissus tissues; the levels of transcription in petals and corona is higher than other tissues and the transcription level at the bud stage was highest. These results show that NtMYB2 is involved in the regulation of anthocyanin biosynthesis pathway and may act as a repressor by down regulating the transcripts of key enzyme genes in Chinese narcissus.

Ectopic Overexpression of a Novel R2R3-MYB, NtMYB2 from Chinese Narcissus Represses Anthocyanin Biosynthesis in Tobacco.

Science.gov (United States)

Anwar, Muhammad; Wang, Guiqing; Wu, Jiacheng; Waheed, Saquib; Allan, Andrew C; Zeng, Lihui

2018-03-28

R2R3 MYB transcription factors play key functions in the regulation of secondary metabolites. In the present study, a R2R3 MYB transcriptional factor NtMYB2 was identified from Chinese narcissus ( Narcissus tazetta L. var. Chinensis Roem) and functionally characterized. NtMYB2 belongs to subgroup 4 of the R2R3 MYB transcription factor family that are related to repressor MYBs involved in the regulation of anthocyanin and flavonoids. Transient expression confirmed that NtMYB2 strongly reduced the red pigmentation induced by MYB- anthocyanin activators in agro-infiltrated tobacco leaves. Ectopic expression of NtMYB2 in tobacco significantly reduced the pigmentation and altered the floral phenotypes in transgenic tobacco flowers. Gene expression analysis suggested that NtMYB2 repressed the transcript levels of structural genes involved in anthocyanin biosynthesis pathway, especially the UFGT gene. NtMYB2 gene is expressed in all examined narcissus tissues; the levels of transcription in petals and corona is higher than other tissues and the transcription level at the bud stage was highest. These results show that NtMYB2 is involved in the regulation of anthocyanin biosynthesis pathway and may act as a repressor by down regulating the transcripts of key enzyme genes in Chinese narcissus.

R-loops: targets for nuclease cleavage and repeat instability.

Science.gov (United States)

Freudenreich, Catherine H

2018-01-11

R-loops form when transcribed RNA remains bound to its DNA template to form a stable RNA:DNA hybrid. Stable R-loops form when the RNA is purine-rich, and are further stabilized by DNA secondary structures on the non-template strand. Interestingly, many expandable and disease-causing repeat sequences form stable R-loops, and R-loops can contribute to repeat instability. Repeat expansions are responsible for multiple neurodegenerative diseases, including Huntington's disease, myotonic dystrophy, and several types of ataxias. Recently, it was found that R-loops at an expanded CAG/CTG repeat tract cause DNA breaks as well as repeat instability (Su and Freudenreich, Proc Natl Acad Sci USA 114, E8392-E8401, 2017). Two factors were identified as causing R-loop-dependent breaks at CAG/CTG tracts: deamination of cytosines and the MutLγ (Mlh1-Mlh3) endonuclease, defining two new mechanisms for how R-loops can generate DNA breaks (Su and Freudenreich, Proc Natl Acad Sci USA 114, E8392-E8401, 2017). Following R-loop-dependent nicking, base excision repair resulted in repeat instability. These results have implications for human repeat expansion diseases and provide a paradigm for how RNA:DNA hybrids can cause genome instability at structure-forming DNA sequences. This perspective summarizes mechanisms of R-loop-induced fragility at G-rich repeats and new links between DNA breaks and repeat instability.

The Depiction of Native Americans in Recent (1991-1998) Secondary American History Textbooks.

Science.gov (United States)

Sanchez, Antonio R.

As a follow-up to studies by R. Costo and J. Henry (1970) and J. Loewen (1995), this study examined 12 current secondary level U.S. history textbooks to evaluate their accuracy in depicting Native Americans. The criteria embodied an authenticity guideline based upon the "Five Great Values" (generosity and sharing, respect for elders and…

77 FR 1656 - Proposed Establishment of Restricted Areas R-5402, R-5403A, R-5403B, R-5403C, R-5403D, R-5403E, R...

Science.gov (United States)

2012-01-11

...-0117; Airspace Docket No. 09-AGL-31] RIN 2120-AI92 Proposed Establishment of Restricted Areas R-5402, R-5403A, R- 5403B, R-5403C, R-5403D, R-5403E, R-5403F; Devils Lake, ND AGENCY: Federal Aviation... Restricted Areas R-5402, R-5403A, R-5403B, R- 5403C, R-5403D, R-5403E, R-5403F; Devils Lake, ND (76 FR 72869...

77 FR 36907 - Establishment of Restricted Areas R-5402, R-5403A, R-5403B, R-5403C, R-5403D, R-5403E, and R...

Science.gov (United States)

2012-06-20

...; Airspace Docket No. 09-AGL-31] Establishment of Restricted Areas R-5402, R-5403A, R-5403B, R- 5403C, R-5403D, R-5403E, and R-5403F; Devils Lake, ND AGENCY: Federal Aviation Administration (FAA), DOT. ACTION... establish Restricted Areas R- 5402, R-5403A, R-5403B, R-5403C, R-5403D, R-5403E, and R-5403F in the vicinity...

Enigmatic Ethiopian endemic rodent Muriculus imberbis (Rüppell 1842) represents a separate lineage within genus Mus

Czech Academy of Sciences Publication Activity Database

Meheretu, Yonas; Šumbera, R.; Bryja, Josef

2015-01-01

Roč. 79, č. 1 (2015), s. 15-23 ISSN 0025-1461 R&D Projects: GA ČR GAP506/10/0983; GA ČR GCP502/11/J070 Institutional support: RVO:68081766 Keywords : Afroalpine * endemic * Ethiopia * Nannomys * phylogeny Subject RIV: EG - Zoology Impact factor: 0.538, year: 2015

Secondary electron emission from solid HD and a solid H2-D2 mixture

DEFF Research Database (Denmark)

Sørensen, H.; Børgesen, P.; Hao-Ming, Chen

1983-01-01

Secondary electron emission from solid HD and a solid 0.6 H2 + 0.4 D2 mixture has been studied for electron and hydrogen ion bombardment at primary energies from 0.5 to 3 keV and 2 to 10 keV/amu, respectively. The yield for solid HD is well explained by a simple stoichiometric model of the low...

Circulating miR-126 and miR-499 reflect progression of cardiovascular disease; correlations with uric acid and ejection fraction

Directory of Open Access Journals (Sweden)

Masoud Khanaghaei

2016-04-01

Full Text Available BackgroundThe aim of this study was to assess plasma levels of endothelium- and heart-associated microRNAs (miRNAs miR-126 and miR-499, respectively, using quantitative reverse transcriptase polymerase chain reaction.MethodsA two-step analysis was conducted on 75 patients undergoing off-pomp coronary artery bypass graft (CABG surgery. Five biomarkers of inflammation and cardiac injury were assessed in addition to the above-mentioned miRNAs.ResultsPlasma concentrations of miRNAs were found to be significantly correlated with plasma levels of cardiac troponin I (cTnI (miR-499, r 0.49, p~0.002; miR-126, r = 0.30, p~0.001, indicating cardiac damage. Data analysis revealed that miR-499 had higher sensitivity and specificity for cardiac injury than miR-126, which reflects more endothelial activation. Interestingly, a strong correlation was observed between both miRNAs and uric acid (UA levels with ventricular contractility measured as ejection fraction (EF (miR-499/EF%, r = 0.58, p~0.004; UA/EF%, r = -0.6, p~0.006; UA/miR-499, r = -0.34; UA/miR-126, r = 0.5, p~0.01.ConclusionsIn patients undergoing CABG, circulating miR-126/499 is associated with presentation of traditional risk factors and reflects post-operative response to injury. Plasma pool of miRNAs likely reflects extracellular miRNAs which are proportional to intracellular miRNA levels. Therefore, circulating levels of these miRNAs have prognostic implications in detection of higher risk of future cardiovascular events.

Magnetic properties of screen-printed (Y0.5Sm0.5)Co5 magnet arrays

International Nuclear Information System (INIS)

Bueno-Baques, D.; Maldonado-Chavez, L.; Hidalgo-Gonzalez, J.L.; Matutes-Aquino, J.A.; Corral-Flores, V.

2007-01-01

(Y 0.5 Sm 0.5 )Co 5 magnet arrays of square μdots of 300 μm were prepared by screen printing. A well controlled paste like ink prepared with the (Y 0.5 Sm 0.5 )Co 5 nanoparticles and a mixture of organic solvent and polymer was used to print different pattern arrays. (Y 0.5 Sm 0.5 )Co 5 nanoparticles were obtained by mechanical milling starting from arc melted ingots and heat treated in Ar atmosphere. Two different heat treatment were considered, resulting in powders with different magnetic properties. The microstructure of the magnet arrays was studied by scanning electron microscopy (SEM). An isotropic homogeneous distribution of the nanoparticles inside the μdots was observed. The final shape of the μdots in the array was found to be highly dependent on the squeeze pressure and speed over the mesh. Magnetic properties were studied by pulsed field magnetometry and vibrating sample magnetometry at room temperature. The micro size arrays showed lower saturation magnetization and a slightly increase in the coercive field. (copyright 2007 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

Germination and sporophytic development of Regnellidium diphyllum Lindman (Marsileaceae in the presence of hexavalent chromium Germinação e desenvolvimento esporofítico de Regnellidium diphyllum Lindman (Marsileaceae na presença de cromo hexavalente

Directory of Open Access Journals (Sweden)

MA. Kieling-Rubio

2010-12-01

Full Text Available Regnellidium diphyllum Lindman is a heterosporous fern, growing in aquatic environments and surrounding wetlands, which is assumed to be threatened by increasing water pollution and disappearance of its natural habitats. Among contaminants, hexavalent chromium - Cr(VI - is known to be present in effluents from some leather tanning factories. Megaspore germination tests were performed using Meyer's solution, at concentrations 0 (control, 0.1, 0.5, 1, 5, 10, 15, 20, 30, 50, and 80 mg.L-1, from a standard solution of Titrisol® 1000 mg.L-1. The primary development of apomictic sporophytes was studied using solutions containing 0.025 to 4.8 mg.L-1 of Cr(VI. The experiments were conducted in a growth chamber at 24 ± 1 ºC and for a 12-hour photoperiod under fluorescent lights, providing a nominal irradiance of 77 µmol.m-2/s. Significant differences in megaspore germination, with subsequent sporophytic development, were verified from 0.5 mg.L-1 Cr(VI concentration onwards. Growth of primary root and primary and secondary leaves was significantly reduced at 3.2 mg.L-1 Cr(VI concentration or higher. Considering the pollution from Cr(VI in some areas of R. diphyllum natural occurrence, these data indicate that low reproductive rates and disappearance of populations are likely to occur in these situations.Regnellidium diphyllum Lindman é uma filicínea heterosporada que se desenvolve em ambientes aquáticos e áreas úmidas circundantes, sendo considerada ameaçada pelo aumento da poluição e desaparecimento dos seus hábitats naturais. Entre os contaminantes, o cromo hexavalente - Cr(VI - é conhecido por estar presente nos efluentes de algumas indústrias de curtimento de couro. Testes de germinação foram realizados em meio líquido de Meyer, com concentrações de 0(controle; 0,1; 0,5; 1; 5; 10; 15; 20; 30; 50; e 80 mg.L-1 de Cr(VI, a partir de uma solução padrão de Titrisol® a 1000 mg.L-1. O desenvolvimento primário dos esporófitos apom

Asymmetric transfer hydrogenation of ketones in aqueous solution catalyzed by Rhodium(III) complexes with C2-symmetric fluorene-ligands containing chiral (1R,2R)-cyclohexane-1,2-diamine

International Nuclear Information System (INIS)

Montalvo-Gonzalez, Ruben; Chavez, Daniel; Aguirre, Gerardo; Parra-Hake, Miguel; Somanathan, Ratnasamy

2010-01-01

Two C 2 -symmetric bis(sulfonamide) ligands containing fluorene-chiral (1R, 2R)-cyclohexane-1,2-diamine were complexed to Rh III (Cp * ) and used as catalyst to reduce aromatic ketones. The corresponding chiral secondary alcohols were obtained in 87-100% ee and 85-99% yield, under asymmetric transfer hydrogenation (ATH) conditions using aqueous sodium formate as the hydride source. With acetophenone, 94% ee and 86-97% yield was achieved with substrate/catalyst (S/C) ratio of 10,000. (author)

Phase, microstructure and microwave dielectric properties of Mg0:95Ni0:05Ti0:98Zr0:02O3 ceramics

Directory of Open Access Journals (Sweden)

Manan Abdul

2015-03-01

Full Text Available Mg0:95Ni0:05Ti0:98Zr0:02O3 ceramics was prepared via conventional solid-state mixed-oxide route. The phase, microstructure and microwave dielectric properties of the sintered samples were characterized using X-ray diffraction (XRD, scanning electron microscopy (SEM and a vector network analyzer. The microstructure comprised of circular and elongated plate-like grains. The semi quantitative analysis (EDS of the circular and elongated grains revealed the existence of Mg0:95Ni0:05T2O5 as a secondary phase along with the parent Mg0:95Ni0:05Ti0:98Zr0:02O3 phase, which was consistent with the XRD findings. In the present study, εr ~17.1, Qufo~195855 ± 2550 GHz and τf ~ -46 ppm/K was achieved for the synthesized Mg0:95Ni0:05Ti0:98Zr0:02O3 ceramics sintered at 1325 °C for 4 h.

Secondary pigmentary glaucoma in patients with underlying primary pigment dispersion syndrome

OpenAIRE

Sivaraman, Kavitha R; Patel, Chirag G; Vajaranant, Thasarat S; Aref, Ahmad A

2013-01-01

Kavitha R Sivaraman, Chirag G Patel, Thasarat S Vajaranant, Ahmad A ArefDepartment of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago School of Medicine, Chicago, IL, USAAbstract: Primary pigment dispersion syndrome (PPDS) is a bilateral condition that occurs in anatomically predisposed individuals. PPDS may evolve into pigmentary glaucoma, but it is difficult to predict which patients will progress. Secondary pigment dispersion is more oft...

5. International seminar on primary and secondary side water chemistry of nuclear power plants

International Nuclear Information System (INIS)

2001-01-01

The major subjects of the meetings are: water chemistry of primary and secondary coolant circuits of PWR type reactors (mainly WWER types), corrosion of steam generators, decontamination processes, treatment of radioactive waste waters and related subjects. All the 29 papers were individually indexed and abstracted for the INIS database. (R.P.)

5. International seminar on primary and secondary side water chemistry of nuclear power plants

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-07-01

The major subjects of the meetings are: water chemistry of primary and secondary coolant circuits of PWR type reactors (mainly WWER types), corrosion of steam generators, decontamination processes, treatment of radioactive waste waters and related subjects. All the 29 papers were individually indexed and abstracted for the INIS database. (R.P.)

Optimized R functions for analysis of ecological community data using the R virtual laboratory (RvLab).

Science.gov (United States)

Varsos, Constantinos; Patkos, Theodore; Oulas, Anastasis; Pavloudi, Christina; Gougousis, Alexandros; Ijaz, Umer Zeeshan; Filiopoulou, Irene; Pattakos, Nikolaos; Vanden Berghe, Edward; Fernández-Guerra, Antonio; Faulwetter, Sarah; Chatzinikolaou, Eva; Pafilis, Evangelos; Bekiari, Chryssoula; Doerr, Martin; Arvanitidis, Christos

2016-01-01

Parallel data manipulation using R has previously been addressed by members of the R community, however most of these studies produce ad hoc solutions that are not readily available to the average R user. Our targeted users, ranging from the expert ecologist/microbiologists to computational biologists, often experience difficulties in finding optimal ways to exploit the full capacity of their computational resources. In addition, improving performance of commonly used R scripts becomes increasingly difficult especially with large datasets. Furthermore, the implementations described here can be of significant interest to expert bioinformaticians or R developers. Therefore, our goals can be summarized as: (i) description of a complete methodology for the analysis of large datasets by combining capabilities of diverse R packages, (ii) presentation of their application through a virtual R laboratory (RvLab) that makes execution of complex functions and visualization of results easy and readily available to the end-user. In this paper, the novelty stems from implementations of parallel methodologies which rely on the processing of data on different levels of abstraction and the availability of these processes through an integrated portal. Parallel implementation R packages, such as the pbdMPI (Programming with Big Data - Interface to MPI) package, are used to implement Single Program Multiple Data (SPMD) parallelization on primitive mathematical operations, allowing for interplay with functions of the vegan package. The dplyr and RPostgreSQL R packages are further integrated offering connections to dataframe like objects (databases) as secondary storage solutions whenever memory demands exceed available RAM resources. The RvLab is running on a PC cluster, using version 3.1.2 (2014-10-31) on a x86_64-pc-linux-gnu (64-bit) platform, and offers an intuitive virtual environmet interface enabling users to perform analysis of ecological and microbial communities based on

Structural and Moessbauer Effect Studies of 0.7Bi0.95Dy0.05FeO3-0.3Pb(Fe0.5Nb0.5)O3 Multiferroic

International Nuclear Information System (INIS)

Stoch, A.; Kulawik, J.; Stoch, P.; Maurin, J.; Zachariasz, P.

2011-01-01

0.7Bi 0.95 Dy 0.05 FeO 3 -0.3Pb(Fe 0.5 Nb 0.5 )O 3 is a multiferroic material which exhibits ferroelectric and antiferromagnetic ordering. In this paper the way of the synthesis of 0.7Bi 0.95 Dy 0.05 FeO 3 -0.3Pb(Fe 0.5 Nb 0.5 )O 3 is presented. The detailed X-ray and Moessbauer effect studies were done and crystal and hyperfine interaction parameters were obtained. (authors)

Average Albedos of Close-in Super-Earths and Super-Neptunes from Statistical Analysis of Long-cadence Kepler Secondary Eclipse Data

Science.gov (United States)

Sheets, Holly A.; Deming, Drake

2017-10-01

We present the results of our work to determine the average albedo for small, close-in planets in the Kepler candidate catalog. We have adapted our method of averaging short-cadence light curves of multiple Kepler planet candidates to long-cadence data, in order to detect an average albedo for the group of candidates. Long-cadence data exist for many more candidates than the short-cadence data, and so we separate the candidates into smaller radius bins than in our previous work: 1-2 {R}\\oplus , 2-4 {R}\\oplus , and 4-6 {R}\\oplus . We find that, on average, all three groups appear darker than suggested by the short-cadence results, but not as dark as many hot Jupiters. The average geometric albedos for the three groups are 0.11 ± 0.06, 0.05 ± 0.04, and 0.23 ± 0.11, respectively, for the case where heat is uniformly distributed about the planet. If heat redistribution is inefficient, the albedos are even lower, since there will be a greater thermal contribution to the total light from the planet. We confirm that newly identified false-positive Kepler Object of Interest (KOI) 1662.01 is indeed an eclipsing binary at twice the period listed in the planet candidate catalog. We also newly identify planet candidate KOI 4351.01 as an eclipsing binary, and we report a secondary eclipse measurement for Kepler-4b (KOI 7.01) of ˜7.50 ppm at a phase of ˜0.7, indicating that the planet is on an eccentric orbit.

Purification of R-phycoerythrin from Gracilaria lemaneiformis by centrifugal precipitation chromatography.

Science.gov (United States)

Gu, Dongyu; Lazo-Portugal, Rodrigo; Fang, Chen; Wang, Zhantong; Ma, Ying; Knight, Martha; Ito, Yoichiro

2018-06-15

Centrifugal precipitation chromatography (CpC) is a powerful chromatographic technique invented in the year 2000 but so far very little applied. The method combines dialysis, counter-current and salting out processes. The separation rotor consists of two identical spiral channels separated by a dialysis membrane (6-8 K MW cut-off) in which the upper channel is eluted with an ammonium sulfate gradient and the lower channel with water, and the mixtures are separated according to their solubility in ammonium sulfate as a chromatographic technique. In the present study, the method was successfully applied for separation and purification of R-phycoerythrin (R-PE), a protein widely used as a fluorescent probe, from the red alga Gracilaria lemaneiformis. The separation was performed with the elution of ammonium sulfate from 50% to 0% in 21.5 h at a flow rate of 0.5 ml/min, while the lower channel was eluted with water at a flow rate of 0.05 ml/min after sample charge, and the column was rotated at 200 rpm. After a single run, the absorbance ratio A 565 /A 280 (a criterion for the purity of R-PE) was increased from 0.5 of the crude to 6.5. The purified R-PE exhibited a typical "three peaks" spectrum with absorbance maximum at 497, 538 and 565 nm. The Native-PAGE showed one single protein band and 20 kDa (subunits α and β) and 30 kDa (subunit γ) can be observed in SDS-PAGE analysis which were consistent with the (αβ) 6 γ subunit composition of R-PE. The results indicated that CpC is an efficient method to obtain protein with the high purity from a complex source. Copyright © 2018 Elsevier B.V. All rights reserved.

Hot rolling effect on the characters of Zr-0.6Nb-0.5Fe-0.5Cr alloy

International Nuclear Information System (INIS)

Sungkono; Siti Aidah

2015-01-01

Characters of Zr-0.6Nb-0.5Fe-0.5Cr alloy after hot rolling have been studied. The objective of this research was to obtain of hot rolling effect on the characteristics of microstructures, hardness and phases formed in Zr-0.6Nb-0.5Fe-0.5Cr alloy. The hot rolling process of alloy carried out at temperature of 800 °C with retention time of 1.5 and 2 hours and a thickness reduction between 5 to 25 %. The results of this experiment showed that the Zr-0.6Nb-0.5Fe-0.5Cr alloy has Widmanstaetten structure with microstructure evolving into deformed columnar grains and deformed elongated grains with increasing thickness reduction. Besides, the longer the retention time at temperature of 800 °C is the larger are the grain structures and formation of α-Zr and Zr_3Fe phase. The hardness of Zr-0.6Nb-0.5Fe-0.5Cr alloy has same trends i.e the larger thickness reduction gives higher hardness. The Zr-0.6Nb-0.5Fe-0.5Cr alloy can under go hot rolling deformation at a thickness reduction of 25 % and the formation of α-Zr and Zr_3Fe can increased of hardness and strength of Zr-0.6 Nb-0.5 Fe-0.5 Cr alloy. (author)

Fundamental Achievements of Ancient Chinese Mathematicians

Czech Academy of Sciences Publication Activity Database

Křížek, Michal; Liu, L.; Šolcová, A.

2005-01-01

Roč. 38, č. 3 (2005), s. 99-107 ISSN 0025-5653 R&D Projects: GA AV ČR(CZ) IAA1019201 Institutional research plan: CEZ:AV0Z10190503 Keywords : Pythagorean theorem * Ludolf number * primality test Subject RIV: BA - General Mathematics

Coverings, Networks and Weak Topologies

Czech Academy of Sciences Publication Activity Database

Dow, A.; Junnila, H.; Pelant, Jan

2006-01-01

Roč. 53, č. 2 (2006), s. 287-320 ISSN 0025-5793 R&D Projects: GA ČR GA201/97/0216 Institutional research plan: CEZ:AV0Z10190503 Keywords : Banach spaces * weak topologies * networks topologies Subject RIV: BA - General Mathematics

From Fermat Numbers to Geometry

Czech Academy of Sciences Publication Activity Database

Křížek, Michal; Luca, F.; Somer, L.

2005-01-01

Roč. 38, č. 2 (2005), s. 56-63 ISSN 0025-5653 R&D Projects: GA AV ČR(CZ) IAA1019201 Institutional research plan: CEZ:AV0Z10190503 Keywords : Pascal triangle * Heron triangle * graph theory Subject RIV: BA - General Mathematics

Influence of acepromazine on the cardiovascular actions of dobutamine in isoflurane-anesthetized horses Influência da acepromazina sobre os efeitos cardiovasculares da dobutamina em cavalos anestesiados com isofluorano

Directory of Open Access Journals (Sweden)

Eduardo Raposo Monteiro

2011-03-01

Full Text Available The influence of acepromazine (ACP on the effectiveness of dobutamine (DBT in increasing blood pressure during isoflurane (ISO anesthesia was evaluated in six horses. On separate occasions, the horses were randomly assigned to receive NaCl 0.9% (Control, ACP 0.025mg kg-1 and ACP 0.05mg kg-1. The experimental treatment was administered prior to induction of anesthesia. Maintenance of anesthesia was performed under conditions of normocapnia with ISO in oxygen. Dobutamine was administered at progressively increasing infusion rates until mean arterial pressure (MAP reached 70mmHg or until a maximum infusion rate of 5.0µg kg-1 min-1. Compared with baseline, DBT increased heart rate, systolic, diastolic and mean blood pressures in all treatments. However, these variables did not differ among treatments. The target MAP (70mmHg was not reached in 2/6, 2/5 and 0/6 horses in the Control, ACP0.025 and ACP0.05 treatments, respectively. The mean dose of DBT to achieve target MAP was 3.5±1.8, 3.7±1.6 and 2.7±1.4µg kg-1 min-1 in the Control, ACP0.025 and ACP0.05 treatments, respectively (P>0.05. Under the conditions of this study, premedication with ACP does not interfere with the effectiveness of DBT in increasing blood pressure in horses anesthetized with ISO.A influência da acepromazina (ACP sobre a capacidade da dobutamina (DBT em elevar a pressão arterial durante a anestesia com isofluorano (ISO foi avaliada em seis equinos. Em ocasiões diferentes, os animais receberam aleatoriamente NaCl 0,9% (Controle, ACP 0,025mg kg-1 e ACP 0,05mg kg-1. O tratamento experimental foi administrado previamente à indução da anestesia. A manutenção da anestesia foi realizada em condições de normocapnia com ISO em oxigênio. A administração de DBT foi iniciada em doses progressivamente crescentes até que o valor de pressão arterial média (PAM atingisse 70mmHg ou até a dose máxima de 5,0µg kg-1 min-1. Comparado ao basal, a administração da DBT

WATER TEMPERATURE and SALINITY - SURFACE WATER, and other parameters collected from R.V. Celtic Explorer in Mid Atlantic Ridge from 2016-05-12 to 2016-05-21 (NCEI Accession 0157069)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains in situ sea surface measurements from R.V. Celtic Explorer in Mid Altlantic Ridge. The survey was conducted between May 12th and May 21, 2016...

Influence of supplementary cementitious materials on the properties of concrete for secondary protection barrier in radioactive waste repositories

Czech Academy of Sciences Publication Activity Database

Koťátková, J.; Čáchová, M.; Bezdička, Petr; Vejmelková, E.; Konvalinka, P.; Zemanová, L.; Černý, R.

2018-01-01

Roč. 760, SI (2018), s. 96-101 ISSN 1662-9795. [Special Concrete and Composites 2017 /14./. Lísek, 10.10.2017-11.10.2017] R&D Projects: GA ČR(CZ) GA17-11635S Institutional support: RVO:61388980 Keywords : Basic physical properties * Mechanical properties * Repository * Secondary protection barrier * Supplementary cementitious materials * Thermal properties Subject RIV: CA - Inorganic Chemistry OBOR OECD: Inorganic and nuclear chemistry

A randomized controlled trial of R-salbutamol for topical treatment of discoid lupus erythematosus

DEFF Research Database (Denmark)

Jemec, G B E; Ullman, S; Goodfield, M

2009-01-01

BACKGROUND: In a recent open pilot trial, R-salbutamol sulphate, a well-known molecule with anti-inflammatory effects, was tested successfully on patients with therapy-resistant discoid lupus erythematosus (DLE). OBJECTIVES: To compare the efficacy and safety of R-salbutamol cream 0.5% vs. placebo...

Phylogenetic position of the giant house bat Scotophilus nigrita (Chiroptera, Vespertilionidae)

Czech Academy of Sciences Publication Activity Database

Vallo, Peter; Benda, P.; Červený, J.; Koubek, Petr

2015-01-01

Roč. 79, č. 2 (2015), s. 225-231 ISSN 0025-1461 R&D Projects: GA ČR GP206/09/P624; GA AV ČR IAA6093404 Institutional support: RVO:68081766 Keywords : cranial morphometrics * cytochrome b * phylogeny * zinc finger protein Y Subject RIV: EG - Zoology Impact factor: 0.538, year: 2015

Secondary side photographic techniques used in characterization of Surry steam generator

International Nuclear Information System (INIS)

Sinclair, R.B.

1984-10-01

Characterization of the generator's secondary side prior to destructive removal of tubing presents a significant challenge. Information must be obtained in a radioactive field (up to 15 R/h) throughout the tightly spaced bundle of steam generator tubes. This report discusses the various techniques employed, along with their respective advantages and disadvantages. The most successful approach to nondestructive secondary side characterization and documentation was through use of in-house developed pinhole cameras. These devices provided accurate photographic documentation of generator condition. They could be fabricated in geometries allowing access to all parts of the generator. Semi-remote operation coupled with large area coverage per investigation and short at-location times resulted in significant personnel exposure advantages. The fabrication and use of pinhole cameras for remote inspection is discussed in detail

Secondary surgical-site infection after coronary artery bypass grafting: A multi-institutional prospective cohort study.

Science.gov (United States)

Gulack, Brian C; Kirkwood, Katherine A; Shi, Wei; Smith, Peter K; Alexander, John H; Burks, Sandra G; Gelijns, Annetine C; Thourani, Vinod H; Bell, Daniel; Greenberg, Ann; Goldfarb, Seth D; Mayer, Mary Lou; Bowdish, Michael E

2018-04-01

To analyze patient risk factors and processes of care associated with secondary surgical-site infection (SSI) after coronary artery bypass grafting (CABG). Data were collected prospectively between February and October 2010 for consenting adult patients undergoing CABG with saphenous vein graft (SVG) conduits. Patients who developed a deep or superficial SSI of the leg or groin within 65 days of CABG were compared with those who did not develop a secondary SSI. Among 2174 patients identified, 65 (3.0%) developed a secondary SSI. Median time to diagnosis was 16 days (interquartile range 11-29) with the majority (86%) diagnosed after discharge. Gram-positive bacteria were most common. Readmission was more common in patients with a secondary SSI (34% vs 17%, P < .01). After adjustment, an open SVG harvest approach was associated with an increased risk of secondary SSI (adjusted hazard ratio [HR], 2.12; 95% confidence interval [CI], 1.28-3.48). Increased body mass index (adjusted HR, 1.08, 95% CI, 1.04-1.12) and packed red blood cell transfusions (adjusted HR, 1.13; 95% CI, 1.05-1.22) were associated with a greater risk of secondary SSI. Antibiotic type, antibiotic duration, and postoperative hyperglycemia were not associated with risk of secondary SSI. Secondary SSI after CABG continues to be an important source of morbidity. This serious complication often occurs after discharge and is associated with open SVG harvesting, larger body mass, and blood transfusions. Patients with a secondary SSI have longer lengths of stay and are readmitted more frequently. Copyright © 2017 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.

R Aqr observing campaign

Science.gov (United States)

Waagen, Elizabeth O.

2016-01-01

Dr. George Wallerstein (University of Washington) has requested AAVSO coverage of the long period/symbiotic variable R Aquarii beginning immediately in support of high resolution spectroscopic observations planned for 2016 January 19 and 21. Several other astronomers, including Drs. Lee Anne Willson (Iowa State University), Ulisse Munari (INAF, Astronomical Observatory of Padua, Italy), and Fred Walter (Stony Brook University) are studying R Aqr closely and additional spectroscopic and other observations are planned for the near future. R Aqr is both a Mira (M) and a symbiotic (ZAND) - it is a close binary system consisting of a hot star and a late-type star (the Mira), both enveloped in nebulosity. As a result, the very interesting light curve shows not only the Mira pulsation but also complex eclipse behavior as the two stars interact. The period of Mira variation is 387.0 days; the eclipse period is 43.6-44 years. The cause of the eclipse is unknown; several theories h! ave been proposed, including a focused accretion stream, a disk or cloud around the secondary, and a triggered mass loss that produces an opaque cloud. Careful investigation of this upcoming event should help to resolve this question. The last eclipse of R Aqr was in 1978. The next eclipse is predicted for 2022, but may be early. The current behavior of R Aqr suggests that the eclipse, which lasts for several years, may either be beginning or its beginning may be imminent. R Aqr was at minimum in early December 2015 at magnitude V=11.4, and is currently at visual magnitude 11.0. During this phase of the approximately 44-year eclipse cycle, at maximum it may be as bright as V 6.0-6.5 but is not expected to become brighter. Beginning immediately, nightly BVRI CCD and DSLR photometry and visual observations are requested. As R Aqr brightens towards maximum and is in range, PEP observations are also requested. Ongoing spectroscopy over the next several years will be interesting to see as the system

ZnO nanorods/ZnS·(1,6-hexanediamine)(0.5) hybrid nanoplates hierarchical heteroarchitecture with improved electrochemical catalytic properties for hydrazine.

Science.gov (United States)

Wu, Zhengcui; Wu, Yaqin; Pei, Tonghui; Wang, Huan; Geng, Baoyou

2014-03-07

Novel hierarchical heteronanostructures of ZnO nanorods/ZnS·(HDA)0.5 (HDA = 1,6-hexanediamine) hybrid nanoplates on a zinc substrate are successfully synthesized on a large scale by combining hydrothermal growth (for ZnO nanorods) and liquid chemical conversion (for ZnS·(HDA)0.5 nanoplates) techniques. The formation of ZnS·(HDA)0.5 hybrid nanoplates branches takes advantage of the preferential binding of 1,6-hexanediamine on specific facets of ZnS, which makes the thickening rate much lower than the lateral growth rate. The ZnS·(HDA)0.5 hybrid nanoplates have a layered structure with 1,6-hexanediamine inserted into interlayers of wurtzite ZnS through the bonding of nitrogen. The number density and thickness of the secondary ZnS·(HDA)0.5 nanoplates can be conveniently engineered by variation of the sulfur source and straightforward adjustment of reactant concentrations such as 1,6-hexanediamine and the sulfur source. The fabricated ZnO/ZnS·(HDA)0.5 heteronanostructures show improved electrochemical catalytic properties for hydrazine compared with the primary ZnO nanorods. Due to its simplicity and efficiency, this approach could be similarly used to fabricate varieties of hybrid heterostructures made of materials with an intrinsic large lattice mismatch.

Evolutionary rate variation and RNA secondary structure prediction

DEFF Research Database (Denmark)

Knudsen, B.; Andersen, E.S.; Damgaard, C.

2004-01-01

Predicting RNA secondary structure using evolutionary history can be carried out by using an alignment of related RNA sequences with conserved structure. Accurately determining evolutionary substitution rates for base pairs and single stranded nucleotides is a concern for methods based on this type...... by applying rates derived from tRNA and rRNA to the prediction of the much more rapidly evolving 5'-region of HIV-1. We find that the HIV-1 prediction is in agreement with experimental data, even though the relative evolutionary rate between A and G is significantly increased, both in stem and loop regions...

R-rated film viewing and adolescent smoking.

Science.gov (United States)

Laugesen, Murray; Scragg, Robert; Wellman, Robert J; DiFranza, Joseph R

2007-12-01

As smoking is very common in R-rated films, we sought to determine if viewing R-rated films is associated with adolescent smoking. Three annual cross-sectional surveys conducted of 88,505 Year 10 students of largely European, Maori, Asian or Pacific Islander ethnicity in secondary schools in New Zealand between 2002 and 2004. Outcomes of interest were: intention to smoke among never smokers; past experimentation with smoking among current non-smokers; current smoking status; and current frequency of smoking. Dose-response relationships were observed between the frequency of viewing R-rated films and all outcome measures controlling for age, gender, ethnicity, peer smoking, parental smoking, socioeconomic status, pocket money and household smoking rules. Compared to never viewing R-rated films, viewing at least weekly nearly tripled the relative risk (2.81; 95% confidence interval 2.57, 3.09) of never smokers being susceptible to smoking, and more than doubled the risk of both past experimentation (2.28; 95% CI 2.12, 2.45) and smoking>/=monthly (2.31; 95% CI 2.10, 2.54). Each of these risks was seen across all ethnic groups. Our results extend the association that has been demonstrated between viewing R-rated films and current smoking in American youth by demonstrating the same association in youth of different ethnic and cultural backgrounds in New Zealand.

Seasonality of primary and secondary production in an Arctic river

Science.gov (United States)

Kendrick, M.; Huryn, A.; Deegan, L.

2011-12-01

Rivers and streams that freeze solid for 8-9 months each year provide excellent examples of the extreme seasonality of arctic habitats. The communities of organisms inhabiting these rivers must complete growth and development during summer, resulting in a rapid ramp-up and down of production over the short ice-free period. The effects of recent shifts in the timing of the spring thaw and autumn freeze-up on the duration and pattern of the period of active production are poorly understood. We are currently investigating: 1) the response of the biotic community of the Kuparuk River (Arctic Alaska) to shifts in the seasonality of the ice-free period, and 2) the community response to increases in phosphorous (P) supply anticipated as the volume of the permafrost active-layer increases in response to climate warming. Here algal production supports a 2-tier web of consumers. We tracked primary and secondary production from the spring thaw through mid-August in a reference reach and one receiving low-level P fertilization. Gross primary production/community respiration (GPP/R) ratios for both reaches were increasing through mid-July, with higher GPP/R in response to the P addition. Understanding the degree of synchrony between primary and secondary production in this Arctic river system will enhance further understanding of how shifts in seasonality affect trophic dynamics.

(Dy0.5Er0.5)Al2: A large magnetocaloric effect material for low-temperature magnetic refrigeration

International Nuclear Information System (INIS)

Gschneidner, K.A. Jr.; Takeya, H.; Moorman, J.O.; Pecharsky, V.K.

1994-01-01

The low-temprature heat capacity and ac and dc magnetic properties of (Dy 0.5 Er 0.5 )Al 2 have been studied as a function of magnetic fields up to ∼10 T. The magnetocaloric effect in (Dy 0.5 Er 0.5 )Al 2 is 30% larger than that of the prototype material, GdPd. Magnetic measurements show that there is no measurable magnetic hysteresis above ∼17 K. These results suggest that (Dy 0.5 Er 0.5 )Al 2 would be a significantly better magnetic refrigerant than GdPd

The quinternary thiophosphate Cs0.5Ag0.5Nb2PS10

Directory of Open Access Journals (Sweden)

Sojeong Park

2010-07-01

Full Text Available The quinternary thiophosphate Cs0.5Ag0.5Nb2PS10, cesium silver tris(disulfido[tetrathiophosphato(V]diniobate(IV, has been prepared from the elements using a CsCl flux. The crystal structure is made up of ∞1[Nb2PS10] chains expanding along [010]. These chains are built up from bicapped trigonal-prismatic [Nb2S12] units and tetrahedral [PS4] groups and are linked through a linear S—Ag—S bridge, forming a two-dimensional layer. These layers then stack on top of each other, completing the three-dimensional structure with an undulating van der Waals gap. The disordered Cs+ ions reside on sites with half-occupation in the voids of this arrangement. Short [2.8843 (5 Å] and long [3.7316 (4 Å] Nb—Nb distances alternate along the chains, and anionic S22− and S2− species are observed. The charge balance of the compound can be represented by the formula [Cs+]0.5[Ag+]0.5[Nb4+]2[PS43−][S22−]3.

Elastic Properties of Ho0.5Er0.5 Single Crystal

DEFF Research Database (Denmark)

Spichkin, Yu.I.; Bohr, Jakob; Tishin, A.M.

1996-01-01

The results of an investigation of the Young's modulus E and the interval friction Q-1 of a Ho0.5Er0.5 single crystal in the basal plane in the temperature range 4.2-400 K are reported. The measurements were carried out by the method of flexural autovibrations of a thin sample with sound frequency...... (3 kHz). The Young's modulus at 4.2 K was measured to be 154 GPa. From the obtained data the magnetic part of the Young's modulus and the Debye temperature theta-D=375 K were calculated. The anomalies on the Young's modulus and the interval friction temperature dependencies corresponding to magnetic...

A study on the superconducting properties of YBa2Cu9-xNbxOy thin films

International Nuclear Information System (INIS)

Srinivas, S.; Bhatnagar, A.K.; Pinto, R.

1994-01-01

Effect of niobium substitution at the copper site in YBa 2 Cu 9 O 7-x was studied in thin film form. The films were deposited by laser ablation technique using the targets of the YBa 2 Cu 3-x Nb x O y where x = 0.0, 0.025, 0.05, 0.1, 0.2, 0.4, 0.8 and 1.0 under identical deposition conditions on SrTiO 9 substrates. Films were characterized by XRD, resistivity, I-V and J c measurements. Films made from x = 0.025 and 0.05 concentrations of Nb substituted targets showed relatively improved superconducting properties compared to that of undoped films. The best 7 realized for x = 0.025 Nb concentration was 1.8 x 10 σ A/cm 2 and for 0.05 Nb concentration it was 3.2x10 σ A/cm 2 at 77K. However, degradation of the superconducting properties, with the increase of x ≥ 0.1 Nb concentration and drastic suppression and complete loss of superconductivity was noticed for x ≥ 0.4. The growth of impurity phase YBa 2 NbO 6 for x = 0.1 and above of Nb concentration was noticed from XRD patterns. However, the site occupancy of Nb could not be confirmed from these studies

Asymmetric transfer hydrogenation of ketones in aqueous solution catalyzed by Rhodium(III) complexes with C2-symmetric fluorene-ligands containing chiral (1R,2R)-cyclohexane-1,2-diamine

Energy Technology Data Exchange (ETDEWEB)

Montalvo-Gonzalez, Ruben [Universidad Autonoma de Nayarit, Tepic, Nay (Mexico). Unidad Academica de Ciencias Quimico Biologicas y Farmaceuticas; Chavez, Daniel; Aguirre, Gerardo; Parra-Hake, Miguel; Somanathan, Ratnasamy, E-mail: somanatha@sundown.sdsu.ed [Instituto Tecnologico de Tijuana, B.C. (Mexico). Centro de Graduados e Investigacion

2010-07-01

Two C{sub 2}-symmetric bis(sulfonamide) ligands containing fluorene-chiral (1R, 2R)-cyclohexane-1,2-diamine were complexed to Rh{sup III}(Cp{sup *}) and used as catalyst to reduce aromatic ketones. The corresponding chiral secondary alcohols were obtained in 87-100% ee and 85-99% yield, under asymmetric transfer hydrogenation (ATH) conditions using aqueous sodium formate as the hydride source. With acetophenone, 94% ee and 86-97% yield was achieved with substrate/catalyst (S/C) ratio of 10,000. (author)

Generation and marketing of secondaries. Situation and potentials; Herstellung und Vermarktung von Sekundaerrohstoffen. Situation, Probleme, Loesungen

Energy Technology Data Exchange (ETDEWEB)

Probst, T.U. [bvse - Bundesverband Sekundaerrohstoffe und Entsorgung e.V., Bonn (Germany)

2007-12-15

For reasons of protection of the environment and the climate waste management is shifted more and more towards the generation of resources meeting the requirements of an industrial society. This development of sustainable use of waste derived resources is supported by the steadily increasing prices for energy and primary sources. National, European, and international politics enhance the generation of secondaries for instance by the 3R initiative of the G8 nations. Thus, waste management is performed to obtain more secondaries, to use their energy contents, and to reduce the hazardous potential in waste flows. Secondaries are used either to substitute primary sources or fuels. For years, medium sized companies extract valuable resource from waste flows, especially since they do not operate disposal sites. Thus, secondary raw materials can be generated, on the background of better prices, more competitive to primary sources out of monofractions and from mixture flows. Besides the use of secondaries in primary markets they created their own markets. To enhance the quantities of secondaries, the various waste flows have to be kept strictly separately from household wastes. Thus, the medium sized companies efficiently fulfil the political and market requirements and generate valuable resources. (orig.)

Effect of Andrographolide‭ Extract on Blood Glucose and Lipid Profile in Rats with Secondary Iron Overload

Directory of Open Access Journals (Sweden)

َArash Mehri Pirayvatlo

2017-01-01

Full Text Available Background & objectives: Iron overload is involved in the pathophysiology of many diseases including diabetes. In fact, the excess iron by creating free radicals makes damage to pancreas and leads to insulin resistance and diabetes. Andrographolide extract has hypoglycemic and antioxidant properties. This study has surveyed the effects of andrographolide on blood glucose and lipid profile in rats with secondary iron overload. Methods: In this experimental study, 36 male Wistar rats were randomly divided into 6 groups: the healthy control group, secondary iron overload group, secondary iron overload groups treated with a dose of 3.5 and 7 mg/kg of andrographolide extract, and andrographolide groups treated with a dose of 3.5 and 7 mg/kg of extract. Iron and extract were injected for 6 and 12 days, respectively. Blood samples were taken for measurement of blood glucose and lipid profiles. Data were analyzed using ANOVA test. Results: The pathological results of samples from liver of animals receiving iron showed that the iron was deposited in the liver tissues. Iron injection significantly increased blood glucose levels compared to healthy control group (p<0.05. In the iron overload group, andrographolide extract with a dose of 3.5 mg/kg or 7 mg/kg significantly decreased blood glucose levels (p<0.05. Iron injections did not increase the serum triglyceride and cholesterollevels. Injections of andrographolide extract with a dose of 3.5 mg/kg and 7 mg/kg, significantly decreased the cholesterol levels compared to iron receiving group (p<0.05. Conclusion: Results of this study showed that the andrographolide with different doses may be effective in the treatment of diabetes by reducing serum glucose and cholesterol levels.

Effects of Sintering Holding Time on the Structural, Electrical and Magnetic Properties of Zn0.95Ni0.05O

Science.gov (United States)

Ginting, M.; Aryanto, D.; Kurniawan, C.; Sari, A. Y.; Subhan, A.; Sudiro, T.; Sebayang, P.; Tarigan, E. R.; Nasruddin, M. N.; Sebayang, K.

2017-05-01

Zn0.95Ni0.05O has been synthesized by mixing 5% mol of NiO into ZnO using solid state reaction and high-speed shaker mill method. The samples were sintered at 900 °C with holding time for 2, 4 and 8 hours. Crystal structure, electrical and magnetic properties of Zn0.95Ni0.05O were characterized by using XRD, I-V, C-V and VSM. XRD results showed that variation of holding time does not change the structure of ZnO and no other secondary phase observed. The value of lattice parameters (a and c) tends to decrease proportionally to the holding time. The Intensity value changes and the peak shifted to a higher 2θ angle due to holding time variation. In general, the conductance of Zn0.95Ni0.05O decreases and the magnetic properties decrease also as the holding time is increased.

Alignment-free comparative genomic screen for structured RNAs using coarse-grained secondary structure dot plots

DEFF Research Database (Denmark)

Kato, Yuki; Gorodkin, Jan; Havgaard, Jakob Hull

2017-01-01

. Methods: Here we present a fast and efficient method, DotcodeR, for detecting structurally similar RNAs in genomic sequences by comparing their corresponding coarse-grained secondary structure dot plots at string level. This allows us to perform an all-against-all scan of all window pairs from two genomes...... without alignment. Results: Our computational experiments with simulated data and real chromosomes demonstrate that the presented method has good sensitivity. Conclusions: DotcodeR can be useful as a pre-filter in a genomic comparative scan for structured RNAs....

Quality control of the NPL-CRC secondary standard system used for activimeters calibration at IPEN, Sao Paulo, Brazil;Ccontrole de qualidade do sistema padrao secundario NPL-CRC utilizado na calibracao de ativimetros no IPEN

Energy Technology Data Exchange (ETDEWEB)

Martins, Elaine W.; Potiens, Maria da P.A. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

2009-07-01

The objective of this study was to establish a quality control program to be applied at the NPL-CRC activimeter secondary standard system, used as reference to comparison in tests made with the work tertiary standard activimeter, Capintec basic CRC{sup R}-15BT, both belonging to the Calibration Laboratory of IPEN. The repeatability, reproducibility and the precision tests were performed using a sealed check source of {sup 133}Ba, from Amersham. It was made 70 series of 10 measurements to each activimeter, totaling 1400 measurements. Considering the variation limit of 5% to precision and reproducibility tests in the nuclear medicine services, recommended by the Brazilian standard CNEN-NN-3.05, the results observed in the behavior of the IPEN activimeter were satisfactory. (author)

Evaluation of the UVB-screening capacity and restorative effects exerted by farnesol gel on UVB-caused sunburn.

Science.gov (United States)

Wu, Guan Xuan; Huang, Han Hsiang; Chang, Huoy Rou; Kuo, Shyh Ming

2018-04-01

Farnesol, a natural 15-carbon organic compound, has various microbiological and cellular activities. It has been found to exert apoptosis-inducing effects against carcinoma cells as well as antiallergic and anti-inflammatory effects in vivo. In the current study, a series of formulations composed of various concentrations of hydroxypropyl methylcellulose (HPMC) with the addition of hyaluronan (HA) and xanthan gum (XG) was designed to evaluate the UVB-screening and H 2 O 2 -eliminating effects of farnesol in normal fibroblasts. Farnesol at 0.005, 0.0075, and 0.01% exhibited significant capacity for H 2 O 2 scavenging; at 0.0025%, it showed insignificant effects. Under 120-min UVB exposure, screening with plural gel composed of 0.0025% farnesol, 0.5% HA, and 0.5% XG containing 1.5% or 2% HPMC retained normal fibroblast viability. After 60-min exposure to UVB, screening with plural gel composed of farnesol, HA, XG, and 0.5%, 1.0%, 1.5%, or 2% HPMC decreased the ratio of the G1 phase and increased ratio of the S phase in comparison with the accumulated cell cycle of the normal fibroblasts without screening. The gel with 2% HPMC displayed the strongest cell cycle-reversal ability. In vivo histopathological results showed that the prepared plural gels with 0.5% or 2% HPMC and farnesol, HA, and XG had greater antiphotoaging and reparative effects against UVB-induced changes and damage in the skin. In conclusion, the current in vitro and in vivo results demonstrated that the prepared plural composed of 0.0025% farnesol, 0.5% HA, 0.5% XG, and 2% HPMC possessed the greatest UVB-screening capacity and the strongest restorative effects on UVB-induced sunburned skin. © 2018 Wiley Periodicals, Inc.

A novel resource for genomics of Triticeae: BAC library specific for the short arm of rye (Secale cereale L.) chromosome 1R (1RS)

Czech Academy of Sciences Publication Activity Database

Šimková, Hana; Šafář, Jan; Suchánková, Pavla; Kovářová, Pavlína; Bartoš, Jan; Kubaláková, Marie; Janda, Jaroslav; Čihalíková, Jarmila; Mago, R.; Lelley, T.; Doležel, Jaroslav

2008-01-01

Roč. 9, č. 237 (2008), s. 101-109 ISSN 1471-2164 R&D Projects: GA ČR GA521/04/0607; GA ČR GP521/05/P257; GA ČR GD521/05/H013; GA MŠk(CZ) LC06004 Institutional research plan: CEZ:AV0Z50380511 Keywords : flow cytometry * flow-sorted chromosomes * BAC library Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 3.926, year: 2008

Three novel serum biomarkers, miR-1, miR-133a, and miR-206 for Limb-girdle muscular dystrophy, Facioscapulohumeral muscular dystrophy, and Becker muscular dystrophy.

Science.gov (United States)

Matsuzaka, Yasunari; Kishi, Soichiro; Aoki, Yoshitsugu; Komaki, Hirofumi; Oya, Yasushi; Takeda, Shin-Ichi; Hashido, Kazuo

2014-11-01

Muscular dystrophies are a clinically and genetically heterogeneous group of inherited myogenic disorders. In clinical tests for these diseases, creatine kinase (CK) is generally used as diagnostic blood-based biomarker. However, because CK levels can be altered by various other factors, such as vigorous exercise, etc., false positive is observed. Therefore, three microRNAs (miRNAs), miR-1, miR-133a, and miR-206, were previously reported as alternative biomarkers for duchenne muscular dystrophy (DMD). However, no alternative biomarkers have been established for the other muscular dystrophies. We, therefore, evaluated whether these miR-1, miR-133a, and miR-206 can be used as powerful biomarkers using the serum from muscular dystrophy patients including DMD, myotonic dystrophy 1 (DM1), limb-girdle muscular dystrophy (LGMD), facioscapulohumeral muscular dystrophy (FSHD), becker muscular dystrophy (BMD), and distal myopathy with rimmed vacuoles (DMRV) by qualitative polymerase chain reaction (PCR) amplification assay. Statistical analysis indicated that all these miRNA levels in serum represented no significant differences between all muscle disorders examined in this study and controls by Bonferroni correction. However, some of these indicated significant differences without correction for testing multiple diseases (P < 0.05). The median values of miR-1 levels in the serum of patients with LGMD, FSHD, and BMD were approximately 5.5, 3.3 and 1.7 compared to that in controls, 0.68, respectively. Similarly, those of miR-133a and miR-206 levels in the serum of BMD patients were about 2.5 and 2.1 compared to those in controls, 1.03 and 1.32, respectively. Taken together, our data demonstrate that levels of miR-1, miR-133a, and miR-206 in serum of BMD and miR-1 in sera of LGMD and FSHD patients showed no significant differences compared with those of controls by Bonferroni correction. However, the results might need increase in sample sizes to evaluate these three miRNAs as

A proteomic approach to investigating gene cluster expression and secondary metabolite functionality in Aspergillus fumigatus.

Directory of Open Access Journals (Sweden)

Rebecca A Owens

Full Text Available A combined proteomics and metabolomics approach was utilised to advance the identification and characterisation of secondary metabolites in Aspergillus fumigatus. Here, implementation of a shotgun proteomic strategy led to the identification of non-redundant mycelial proteins (n = 414 from A. fumigatus including proteins typically under-represented in 2-D proteome maps: proteins with multiple transmembrane regions, hydrophobic proteins and proteins with extremes of molecular mass and pI. Indirect identification of secondary metabolite cluster expression was also achieved, with proteins (n = 18 from LaeA-regulated clusters detected, including GliT encoded within the gliotoxin biosynthetic cluster. Biochemical analysis then revealed that gliotoxin significantly attenuates H2O2-induced oxidative stress in A. fumigatus (p>0.0001, confirming observations from proteomics data. A complementary 2-D/LC-MS/MS approach further elucidated significantly increased abundance (p<0.05 of proliferating cell nuclear antigen (PCNA, NADH-quinone oxidoreductase and the gliotoxin oxidoreductase GliT, along with significantly attenuated abundance (p<0.05 of a heat shock protein, an oxidative stress protein and an autolysis-associated chitinase, when gliotoxin and H2O2 were present, compared to H2O2 alone. Moreover, gliotoxin exposure significantly reduced the abundance of selected proteins (p<0.05 involved in de novo purine biosynthesis. Significantly elevated abundance (p<0.05 of a key enzyme, xanthine-guanine phosphoribosyl transferase Xpt1, utilised in purine salvage, was observed in the presence of H2O2 and gliotoxin. This work provides new insights into the A. fumigatus proteome and experimental strategies, plus mechanistic data pertaining to gliotoxin functionality in the organism.

Chemical degradation of trimethyl phosphate as surrogate for organo-phosporus pesticides on nanostructured metal oxides

Czech Academy of Sciences Publication Activity Database

Štengl, Václav; Henych, Jiří; Matys Grygar, Tomáš; Pérez, Raul

2015-01-01

Roč. 61, JAN (2015), s. 259-269 ISSN 0025-5408 R&D Projects: GA ČR(CZ) GAP106/12/1116 Institutional support: RVO:61388980 Keywords : Nanostructured oxides * Stoichiometric degradation * Trimethyl phosphate Subject RIV: CA - Inorganic Chemistry Impact factor: 2.435, year: 2015

Spectral analysis of the diffusion operator with random jumps from the boundary

Czech Academy of Sciences Publication Activity Database

Kolb, M.; Krejčiřík, David

2016-01-01

Roč. 284, 3-4 (2016), s. 877-900 ISSN 0025-5874 R&D Projects: GA ČR(CZ) GA14-06818S Institutional support: RVO:61389005 Keywords : self-adjoint operators * eigenvalues * eigenfunctions Subject RIV: BE - Theoretical Physics Impact factor: 0.738, year: 2016