10,170 flawless welds

CERN Multimedia

Antonella Del Rosso

2014-01-01

The welding of tubes containing the principal current-carrying busbars in the LHC magnets was one of the main activities of the SMACC project. After a year of preparation and another of intense activity in the tunnel, the last weld was completed on Wednesday 14 May. Over 10,170 welds have been inspected and not a single fault has been found.    The welder (above) creates the weld using an orbital welding machine (below) specifically designed for CERN. Each of the eight sectors of the LHC contains around 210 interconnects between the superconducting magnets. Consolidating these interconnections was the SMACC project’s primary objective. One of the last jobs before closing the interconnects is the welding of the M lines: each has a 104 mm diameter and a radial clearance of just 45 mm. In total: 10,170 welds carried out in a single year of activities. A true challenge, which was carried out by a team of 30 highly specialised welders, working under the supervision o...

33 CFR 207.170d - Taylor Creek, navigation lock (S-193) across the entrance to Taylor Creek at Lake Okeechobee...

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Taylor Creek, navigation lock (S-193) across the entrance to Taylor Creek at Lake Okeechobee, Okeechobee, Fla.; use, administration..., DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE NAVIGATION REGULATIONS § 207.170d Taylor Creek, navigation lock...

7 CFR 65.170 - Ground lamb.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Ground lamb. 65.170 Section 65.170 Agriculture... OF BEEF, PORK, LAMB, CHICKEN, GOAT MEAT, PERISHABLE AGRICULTURAL COMMODITIES, MACADAMIA NUTS, PECANS, PEANUTS, AND GINSENG General Provisions Definitions § 65.170 Ground lamb. Ground lamb means comminuted...

13 CFR 120.170 - Flood insurance.

Science.gov (United States)

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Flood insurance. 120.170 Section 120.170 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS LOANS Policies Applying to All Business Loans Requirements Imposed Under Other Laws and Orders § 120.170 Flood insurance...

49 CFR 28.170 - Compliance procedures.

Science.gov (United States)

2010-10-01

... 49 Transportation 1 2010-10-01 2010-10-01 false Compliance procedures. 28.170 Section 28.170 Transportation Office of the Secretary of Transportation ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE DEPARTMENT OF TRANSPORTATION § 28.170 Compliance...

Comparative study of in vitro antibacterial activity of leaves, bark, heart wood and seed extracts of Caesalpinia sappan L.

Directory of Open Access Journals (Sweden)

Arunkumar Naik Bukke

2015-11-01

Full Text Available Objective: To evaluate and compare the maximum antimicrobial activity by screening different parts of Caesalpinia sappan L. extracted in different solvents against Salmonella ebony (MTCC 3384 (S. ebony, Klebsiella pneumoniae (MTCC 432 (K. pneumoniae, Escherichia coli (MTCC 443 (E. coli and Bacillus subtilis (MTCC 10619 (B. subtilis. Methods: Dried plant parts were extracted with petroleum ether, methanol, chloroform and water by Soxhlet extraction method. The extracts were tested against S. ebony, K. pneumoniae, E. coli and B. subtilis by using the agar well diffusion method. Results: Among the above solvents, the methanol and chloroform and aqueous extracts of leaves, seeds, bark and heart wood showed strong antibacterial activity. The inhibition zone for heart wood extracts against K. pneumoniae was (30.333 ± 0.330 mm in methanol, chloroform (28.166 ± 0.730 mm and aqueous extract (28.166 ± 0.170 mm; for B. subtilis, that was (27.333 ± 0.440 mm in methanol, (27.166 ± 0.170 mm in chloroform, (26.166 ± 0.440 mm in aqueous extract and least in petroleum ether (12.660 ± 0.170 mm. The leaf extracts in methanol showed maximum antibacterial activity against S. ebony as seen by the inhibition zone (16.000 ± 0.290 mm and K. pneumoniae (13.000 ± 0.290 mm. The maximum antibacterial response of the seed extract against K. pneumoniae was observed in chloroform solvent (14.000 ± 0.580 mm followed by aqueous extract (13.833 ± 0.600 mm. No response was observed in petroleum ether and methanol. Conclusions: The heart wood extracts showed the highest antibacterial activity having a minimal inhibition concentration of 2 mg/mL in all three solvents against the four bacterial strains, except petroleum ether where MIC was 5 mg/mL against E. coli and B. subtilis. The aqueous and methanolic extracts of bark showed minimal inhibition concentrations of 5 mg/ mL and 2 mg/mL against K. pneumoniae respectively whereas aqueous extract of bark showed a minimal

40 CFR 68.170 - Prevention program/Program 2.

Science.gov (United States)

2010-07-01

... (CONTINUED) CHEMICAL ACCIDENT PREVENTION PROVISIONS Risk Management Plan § 68.170 Prevention program/Program 2. (a) For each Program 2 process, the owner or operator shall provide in the RMP the information... the process. (c) The name(s) of the chemical(s) covered. (d) The date of the most recent review or...

42 CFR 457.170 - Withdrawal process.

Science.gov (United States)

2010-10-01

... 42 Public Health 4 2010-10-01 2010-10-01 false Withdrawal process. 457.170 Section 457.170 Public... Plans for Child Health Insurance Programs and Outreach Strategies § 457.170 Withdrawal process. (a... amendment, or any portion of a proposed State plan or plan amendment, at any time during the review process...

Increased cerebral oxygen extraction capacity in patients with Alzheimer’s disease

DEFF Research Database (Denmark)

Eskildsen, Simon Fristed; Gyldensted, Louise; Nagenthiraja, Kartheeban

Vascular risk factors are suspected to play a role in the etiology of Alzheimer’s disease. Recently, a model that relates capillary dysfunction to the development of AD was proposed [1]. The model predicts that increased capillary dysfunction leads to increased oxygen extraction in order to support...

Draft genome sequence of Burkholderia sordidicola S170, a potential plant growth promoter isolated from coniferous forest soil in the Czech Republic

DEFF Research Database (Denmark)

Lladó, Salvador; Xu, Zhuofei; Sørensen, Søren Johannes

2014-01-01

Burkholderia species are key players in the accumulation of carbon from cellulose decomposition in coniferous forest ecosystems. We report here the draft genome of Burkholderia sordidicola strain S170, containing features associated with known genes involved in plant growth promotion...

Thermal Properties of Wood-Plastic Composites Prepared from Hemicellulose-extracted Wood Flour

Directory of Open Access Journals (Sweden)

A.A. Enayati

2013-01-01

Full Text Available Hemicellulose of Southern Yellow Pine wood spices was extracted by pressurized hot water at three different temperatures: 140°C, 155°C and 170°C. Compounding with PP (polypropylene was performed by extrusion after preparing wood flour and sieving to determine its mesh size. The ratio of wood to polymer was 50:50 based on oven-dry weight of wood flour. All extraction treatments and control samples were compounded under two sets of conditions, without and with 2% MAPP as coupling agent. Injection molding was used to make tensile test samples (dogbone from the pellets made by extrusion. Thermal properties of wood-plastic composites were studied by TGA and DSC while the thermal stability of pretreated wood flours, PP and MAPP were studied by TGA as well. The greater weight loss of wood materials was an indication that higher treatment temperature increases the extractability of hemicellulose. The removal of hemicellulose by extraction improves thermal stability of wood flour, especially for extraction at 170°C. Wood-plastic composites made from extracted fibers at 170°C showed the highest thermal stability. Coupling agent did not have a significant effect on thermal stability but it improved the degree of crystallinity of the composites.Surface roughness of wood fiber increased after treatment. Extraction of hemicellulose increased the degree of crystallinity but it was not significant except for samples from treated wood flour at 170°C and with MAPP.

Determination of S17(0) from transfer reactions

International Nuclear Information System (INIS)

Tribble, R.E.; Azhari, A.; Clark, H.L.; Gagliardi, C.A.; Lui, Y.; Mukhamedzhanov, A.M.; Sattarov, A.; Trache, L.; Burjan, V.; Cejpek, J.; Kroha, V.; Piskor, S.; Vincour, J.

1998-01-01

The S-factor for the direct capture reaction 7 Be(p,γ) 8 B can be found at astrophysical energies from the asymptotic normalization coefficients which provide the normalization of the tails of the overlap functions for 8 B→ 7 Be+p. Peripheral transfer reactions offer a technique to determine these asymptotic normalization coefficients. As a test of the technique, the 16 O( 3 He,d) 17 F reaction has been used to determine asymptotic normalization coefficients for transitions to the ground and first excited states of 17 F. The S-factors for 16 O(p,γ) 17 F calculated from these 17 F→ 16 O+p asymptotic normalization coefficients are found to be in very good agreement with recent measurements. Following the same technique, the 10 B( 7 Be, 8 B) 9 Be reaction has been used to measure the asymptotic normalization coefficient for 7 Be(p,γ) 8 B. This result provides an indirect determination of S 17 (0). copyright 1998 American Institute of Physics

TAF(II)170 interacts with the concave surface of TATA-binding protein to inhibit its DNA binding activity.

Science.gov (United States)

Pereira, L A; van der Knaap, J A; van den Boom, V; van den Heuvel, F A; Timmers, H T

2001-11-01

The human RNA polymerase II transcription factor B-TFIID consists of TATA-binding protein (TBP) and the TBP-associated factor (TAF) TAF(II)170 and can rapidly redistribute over promoter DNA. Here we report the identification of human TBP-binding regions in human TAF(II)170. We have defined the TBP interaction domain of TAF(II)170 within three amino-terminal regions: residues 2 to 137, 290 to 381, and 380 to 460. Each region contains a pair of Huntington-elongation-A subunit-Tor repeats and exhibits species-specific interactions with TBP family members. Remarkably, the altered-specificity TBP mutant (TBP(AS)) containing a triple mutation in the concave surface is defective for binding the TAF(II)170 amino-terminal region of residues 1 to 504. Furthermore, within this region the TAF(II)170 residues 290 to 381 can inhibit the interaction between Drosophila TAF(II)230 (residues 2 to 81) and TBP through competition for the concave surface of TBP. Biochemical analyses of TBP binding to the TATA box indicated that TAF(II)170 region 290-381 inhibits TBP-DNA complex formation. Importantly, the TBP(AS) mutant is less sensitive to TAF(II)170 inhibition. Collectively, our results support a mechanism in which TAF(II)170 induces high-mobility DNA binding by TBP through reversible interactions with its concave DNA binding surface.

41 CFR 105-8.170-13 - Delegation.

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Delegation. 105-8.170-13 Section 105-8.170-13 Public Contracts and Property Management Federal Property Management Regulations... HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY GENERAL SERVICES ADMINISTRATION § 105-8.170-13 Delegation...

7 CFR 1427.170 - Quantity for loan.

Science.gov (United States)

2010-01-01

... to the preservation or safety of the loan collateral. Loans may be made on a lower percentage basis... 7 Agriculture 10 2010-01-01 2010-01-01 false Quantity for loan. 1427.170 Section 1427.170... OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS COTTON Recourse Seed Cotton Loans § 1427.170...

Ultrasonic-assisted extraction and in vitro antioxidant activity of polysaccharides from Agaricus bisporus.

Science.gov (United States)

Qiao, De-Liang; Zhao, Feng; Huang, Hai-Zhong; Fan, Chun-Chun; Han, Lei

2012-08-01

To optimize ultrasonic-assisted extraction parameters of polysaccharides from Agaricus bisporus and evaluate antioxidant activities of A. bisporus polysaccharides. Polysaccharides from A. bisporus was extracted by using methods of ultrasonic-assisted hot water lixiviation, ethanol precipitation, Sevag's deproteination and ethanol precipitation again. Extraction temperature, extraction time, ratio of water to raw material and ultrasonic power were selected in single-factor tests. Based on the single-factor tests, parameters combination for the ultrasonic-assisted extraction of A. bisporus polysaccharides was optimized by using four-factor-three-level orthogonal test. Antioxidant activities (reductive potential, superoxide anion scavenging activity and H2O2 scavenging activity) of A. bisporus polysaccharides were evaluated in vitro. Optimum conditions for the extracting of A. bisporus polysaccharides were extracting temperature 65 degrees C, extracting time 40 min, ratio of water to raw material 30 mL/g and ultrasonic power 170 w. Practicing this optimal condition, extraction yield of polysaccharides from A. bisporus was 5.6 014%. In crude polysaccharides of A. bisporus, carbohydrates content, determined by applying the phenol-sulfuric acid method, was 75.48%. Polysaccharides of A. bisporus could reduce ferric ion, scavenge superoxide anion and hydrogen peroxide in a dose-dependent manner. Utrasonic-assisted extraction could be used in the extracting of A. bisporus polysaccharides. Polysaccharides of A. bisporus, had direct and potent antioxidant activities, might be developed and utilized as natural antioxidant.

Increased Dietary Intake of Saturated Fatty Acid Heptadecanoic Acid (C17:0) Associated with Decreasing Ferritin and Alleviated Metabolic Syndrome in Dolphins

Science.gov (United States)

Venn-Watson, Stephanie K.; Parry, Celeste; Baird, Mark; Stevenson, Sacha; Carlin, Kevin; Daniels, Risa; Smith, Cynthia R.; Jones, Richard; Wells, Randall S.; Ridgway, Sam; Jensen, Eric D.

2015-01-01

Similar to humans, bottlenose dolphins (Tursiops truncatus) can develop metabolic syndrome and associated high ferritin. While fish and fish-based fatty acids may protect against metabolic syndrome in humans, findings have been inconsistent. To assess potential protective factors against metabolic syndrome related to fish diets, fatty acids were compared between two dolphin populations with higher (n = 30, Group A) and lower (n = 19, Group B) mean insulin (11 ± 12 and 2 ± 5 μIU/ml, respectively; P dolphins. Capelin, a common dietary fish for Group A, had no detectable C17:0, while pinfish and mullet, common in Group B’s diet, had C17:0 (41 and 67 mg/100g, respectively). When a modified diet adding 25% pinfish and/or mullet was fed to six Group A dolphins over 24 weeks (increasing the average daily dietary C17:0 intake from 400 to 1700 mg), C17:0 serum levels increased, high ferritin decreased, and blood-based metabolic syndrome indices normalized toward reference levels. These effects were not found in four reference dolphins. Further, higher total serum C17:0 was an independent and linear predictor of lower ferritin in dolphins in Group B dolphins. Among off the shelf dairy products tested, butter had the highest C17:0 (423mg/100g); nonfat dairy products had no detectable C17:0. We hypothesize that humans’ movement away from diets with potentially beneficial saturated fatty acid C17:0, including whole fat dairy products, could be a contributor to widespread low C17:0 levels, higher ferritin, and metabolic syndrome. PMID:26200116

21 CFR 161.170 - Canned Pacific salmon.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Canned Pacific salmon. 161.170 Section 161.170... § 161.170 Canned Pacific salmon. (a) Identity. (1) Canned Pacific salmon is the food prepared from one... forms of canned Pacific salmon are processed from fish prepared by removing the head, gills, and tail...

48 CFR 1509.170-4 - Definitions.

Science.gov (United States)

2010-10-01

... Section 1509.170-4 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY ACQUISITION PLANNING CONTRACTOR QUALIFICATIONS Contractor Performance Evaluations 1509.170-4 Definitions. (a) Contractor Performance Report is an evaluation of a contractor's performance for a specified period of time...

34 CFR 1200.170 - Compliance procedures.

Science.gov (United States)

2010-07-01

... 34 Education 3 2010-07-01 2010-07-01 false Compliance procedures. 1200.170 Section 1200.170 Education Regulations of the Offices of the Department of Education (Continued) NATIONAL COUNCIL ON... agency shall notify the Architectural and Transportation Barriers Compliance Board upon receipt of any...

27 CFR 20.170 - Physical inventory.

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Physical inventory. 20.170... Users of Specially Denatured Spirits Inventory and Records § 20.170 Physical inventory. Once in each... physical inventory of each formula of new and recovered specially denatured spirits. (Approved by the...

48 CFR 229.170-3 - Reports.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Reports. 229.170-3 Section... DEFENSE GENERAL CONTRACTING REQUIREMENTS TAXES General 229.170-3 Reports. The contracting officer shall submit a report to the designated Security Assistance Office when a foreign government or entity imposes...

21 CFR 211.170 - Reserve samples.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Reserve samples. 211.170 Section 211.170 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL... of deterioration unless visual examination would affect the integrity of the reserve sample. Any...

25 CFR 170.812 - What is emergency maintenance?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false What is emergency maintenance? 170.812 Section 170.812 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN RESERVATION ROADS PROGRAM BIA Road Maintenance § 170.812 What is emergency maintenance? Emergency maintenance is work that...

Antioxidant mechanism of black garlic extract involving nuclear factor erythroid 2-like factor 2 pathway.

Science.gov (United States)

Ha, Ae Wha; Kim, Woo Kyoung

2017-06-01

Although studies have revealed that black garlic is a potent antioxidant, its antioxidant mechanism remains unclear. The objective of this study was to determine black garlic's antioxidant activities and possible antioxidant mechanisms related to nuclear factor erythroid 2-like factor 2 (Nrf2)-Keap1 complex. After four weeks of feeding rats with a normal fat diet (NF), a high-fat diet (HF), a high-fat diet with 0.5% black garlic extract (HF+BGE 0.5), a high-fat diet with 1.0% black garlic extract (HF+BGE 1.0), or a high-fat diet with 1.5% black garlic extract (HF+BGE 1.5), plasma concentrations of glucose, insulin,homeostatic model assessment of insulin resistance (HOMA-IR) were determined. As oxidative stress indices, plasma concentrations of thiobarbituric acid reactive substances (TBARS) and 8-isoprostaglandin F2α (8-iso-PGF) were determined. To measure antioxidant capacities, plasma total antioxidant capacity (TAC) and activities of antioxidant enzymes in plasma and liver were determined. The mRNA expression levels of antioxidant related proteins such as Nrf2, NAD(P)H: quinone-oxidoreductase-1 (NQO1), heme oxygenase-1 (HO-1), glutathione reductase (GR), and glutathione S-transferase alpha 2 (GSTA2) were examined. Plasma glucose level, plasma insulin level, and HOMA-IR in black garlic supplemented groups were significantly ( P concentration and TAC in the HF+BGE 1.5 group were significantly decreased compared to those of the HF group. The activities of catalase and glutathione peroxidase were significantly ( P antioxidant systems in rats fed with black garlic extract were related to mRNA expression levels of Nrf2 related genes.

46 CFR 154.170 - Outer hull steel plating.

Science.gov (United States)

2010-10-01

... 46 Shipping 5 2010-10-01 2010-10-01 false Outer hull steel plating. 154.170 Section 154.170... STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Hull Structure § 154.170 Outer hull steel plating. (a) Except as required in paragraph (b) of this section, the...

Method of extraction under pressure of fossil material

Energy Technology Data Exchange (ETDEWEB)

Fredenmark, G L

1942-02-24

A method is described of extraction under pressure of fossil material, such as coal, brown coal (lignite), peat, oil shale. It is characterized by carrying out the process of extraction by utilization of fractions of shale oils and/or peat tar with a boiling point above 170/sup 0/C and under such as pressure that the medium of extraction is in a liquid state.

Biosynthesis of CdS nanoparticles in banana peel extract.

Science.gov (United States)

Zhou, Guang Ju; Li, Shuo Hao; Zhang, Yu Cang; Fu, Yun Zhi

2014-06-01

Cadmium sulfide (CdS) nanoparticles (NPs) were synthesized by using banana peel extract as a convenient, non-toxic, eco-friendly 'green' capping agent. Cadmium nitrate and sodium sulfide are main reagents. A variety of CdS NPs are prepared through changing reaction conditions (banana extracts, the amount of banana peel extract, solution pH, concentration and reactive temperature). The prepared CdS colloid displays strong fluorescence spectrum. X-ray diffraction analysis demonstrates the successful formation of CdS NPs. Fourier transform infra-red (FTIR) spectrogram indicates the involvement of carboxyl, amine and hydroxyl groups in the formation of CdS NPs. Transmission electron microscope (TEM) result reveals that the average size of the NPs is around 1.48 nm.

46 CFR 170.200 - Estimated lightweight vertical center of gravity.

Science.gov (United States)

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Estimated lightweight vertical center of gravity. 170... Centers of Gravity § 170.200 Estimated lightweight vertical center of gravity. (a) Each tank vessel that... calculations required by §§ 170.170 and 172.065, the vertical center of gravity of a tank vessel in the...

Risk factors of osteonecrosis of the jaw after tooth extraction in osteoporotic patients on oral bisphosphonates

Energy Technology Data Exchange (ETDEWEB)

Jeong, Ho Gui; Hwang, Jae Joon; Lee, Jeong Hee; Kim, Young Hyun; Na, Ji Yeon; Han, Sang Sun [Dept. of Oral and Maxillofacial Radiology, Yonsei University, College of Dentistry, Seoul (Korea, Republic of)

2017-03-15

The aim of this study was to investigate the incidence of bisphosphonate-related osteonecrosis of the jaw (BRONJ) after tooth extraction in patients with osteoporosis on oral bisphosphonates in Korea and to evaluate local factors affecting the development of BRONJ. The clinical records of 320 patients who underwent dental extraction while receiving oral bisphosphonates were reviewed. All patients had a healing period of more than 6 months following the extractions. Each patient's clinical record was used to assess the incidence of BRONJ; if BRONJ occurred, a further radiographic investigation was carried out to obtain a more definitive diagnosis. Various local factors including age, gender, extraction site, drug type, duration of administration, and C-terminal telopeptide (CTx) level were retrieved from the patients' clinical records for evaluating their effect on the incidence of BRONJ. Among the 320 osteoporotic patients who underwent tooth extraction, 11 developed BRONJ, reflecting an incidence rate of 3.44%. Out of the local factors that may affect the incidence of BRONJ, gender, drug type, and CTx level showed no statistically significant effects, while statistically significant associations were found for age, extraction site, and duration of administration. The incidence of BRONJ increased with age, was greater in the mandible than the maxilla, and was associated with a duration of administration of more than 3 years. Tooth extraction in patients on oral bisphosphonates requires careful consideration of their age, the extraction site, and the duration of administration, and close postoperative follow-up should be carried out to facilitate effective early management.

33 CFR 110.170 - Lockwoods Folly Inlet, N.C.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Lockwoods Folly Inlet, N.C. 110.170 Section 110.170 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.170 Lockwoods Folly Inlet, N.C. (a) Explosives...

Detection of calmodulin binding protein at 170 KDA in BALB, AKR, DON and chicken granulosa cells

International Nuclear Information System (INIS)

Selinfreund, R.; Lin, P.H.; Marrone, B.; Wharton, W.

1987-01-01

Calmodulin (CAM) has been shown to bind to the epidermal growth factor (EGF) receptor (170 kDa) and is phosphorylated in a EGF dependent manner in the A431 human epidermoid carcinoma cells. In the present study, they report 125 I-CAM binding to a 170 kDa protein detected in cell membrane vesicles of Balb/3T3, AKR, DON and chicken granulosa cells. Purified plasma membranes from these cells were resolved via electrophoresis (without heat denaturation) and electroblotted onto nictrocellulose paper. Upon hybridizing against 125 I-CAM, a distinct autoradiographic band occurred at 170 kDa for all the cells lines under study. The binding of CAM is specific and can be displaced with the addition of excess unlabeled CAM. The result suggest that 125 I-CAM may bind to the 170 kDa EGF receptor in BALB, AKR, DON and chicken granulosa cells

25 CFR 170.415 - What is pre-project planning?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false What is pre-project planning? 170.415 Section 170.415... PROGRAM Planning, Design, and Construction of Indian Reservation Roads Program Facilities Long-Range Transportation Planning § 170.415 What is pre-project planning? (a) Pre-project planning is part of overall...

48 CFR 1602.170-7 - Experience-rate.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Experience-rate. 1602.170-7 Section 1602.170-7 Federal Acquisition Regulations System OFFICE OF PERSONNEL MANAGEMENT FEDERAL EMPLOYEES... groups, including mental health benefits capitation rates, per diems, and DRG payments. [70 FR 31378...

Effect of anti-inflamentation extracts from Korean traditional medicinal herb

Directory of Open Access Journals (Sweden)

Zhang Xiaowan

2014-09-01

Full Text Available Five Mix Plant Extracts according to different extraction solvents were assessed for its cell viability and anti-inflammatory activity by in vitro methods. The single plant extract was extracted with 70% ethanol(EtOH and the mix plants(C.kousa, R.multiflora, T.nucifera, M.basjoo and S.glabra were extracted with EtOH 30%, 70%; Butylene Glycol(BG 30%, 70%; Propylene Glycol(PG 30%, 70%; Distilled Water(D.W. Cell viability was measured using the Micro culture tetrazolium (MTT assay method and Human fibroblast cells, CCD 1102 KERTr were used. The plant extracts with the maximum concentration that none toxic to the cells were evaluated for anti-inflammatory activity. Anti-inflammatory activity was evaluated using lipoxygenase inhibition assay method. A dose response curve was plotted to determine the IC50 values. Results showed that, at the 5 kinds of single plant extracts by 70% EtOH extraction solvent, it showed the IC50 was 280ug/ml of S1, 370ug/ml of S2, 380ug/ml of S3, 170ug/ml of S4 and 190ug/ml of S5. At the mix plant extracts by 7 kinds of extraction solvents (70%, 30% EtOH; 70%, 30% BG; 70%, 30% PG; D.W, it showed the IC50 was 140ug/ml of M E70, 140ug/ml of M E30, 120ug/ml of M BG70, 110ug/ml of M BG30, 120ug/ml of M PG70, 136ug/ml of M PG30 and 120ug/ml of M D.W. From the results, it is concluded that when these five plants mixed before extraction, it will extract more active ingredients with anti-inflammatory effects. Further study we will analyzing plants effective single compound using high performance liquid chromatography (HPLC profiling and progressing the experiments in vivo.

21 CFR 170.38 - Determination of food additive status.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Determination of food additive status. 170.38... (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) FOOD ADDITIVES Food Additive Safety § 170.38 Determination of food additive status. (a) The Commissioner may, in accordance with § 170.35(b)(4) or (c)(5...

Preliminary investigations on the effects of a Strongylus vulgaris larval extract, mononuclear factors and platelet factors on equine smooth muscle cells in vitro.

Science.gov (United States)

Morgan, S J; Storts, R W; Stromberg, P C; Sowa, B A; Lay, J C

1989-01-01

Factors involved in the proliferation of equine vascular smooth muscle cells were studied in vitro. The most prominent proliferative responses in cultured vascular smooth muscle cells were induced by Strongylus vulgaris larval antigen extract (LAE) and platelet-derived factors. Less significant proliferative responses were obtained with conditioned media from S. vulgaris LAE stimulated and from unstimulated equine mononuclear leukocytes. Additionally, vascular smooth muscle cells exposed to S. vulgaris LAE developed numerous perinuclear vacuoles and were more spindle-shaped than control or smooth muscle cells exposed to other factors. Equine mononuclear leukocytes exposed to LAE developed prominent morphological changes, including enlargement, clumping and increased numbers of mitotic figures.

An extraction of the skewing factor from DESY-HERA data

International Nuclear Information System (INIS)

Favart, Laurent; Machado, Magno V.T.; Schoeffel, Laurent

2007-01-01

In this contribution we present recent investigation on the extraction of the skewing factor, defined as the ratio of the imaginary parts of the amplitudes ImA (gamma * p → gamma * p) / ImA (gamma * p → gamma p). This factor is extracted from the data using the recent DVCS and the inclusive inelastic cross section measurements at DESY-HERA. We compare the results to the theoretical predictions for NLO QCD and the color dipole approach. (author)

The impact of s- anti s asymmetry on the strange electromagnetic form factor

Energy Technology Data Exchange (ETDEWEB)

Ghasempour Nesheli, Ali [Islamic Azad University, Department of Physics, Shiraz Branch, Shiraz (Iran, Islamic Republic of)

2016-09-15

The existence of the strange quark asymmetry in the nucleon sea has been indicated by both the experimental and theoretical analyses. Although it is well known that the s- anti s asymmetry is important for some processes in high-energy hadron collisions, it has also been indicated that it can be related to the strange Dirac form factor F{sub 1}{sup s}. In this work, we have studied the impact of s- anti s asymmetry and its uncertainty from various modern parton distribution functions (PDFs) on F{sub 1} {sup s} and compared the obtained results with the available experimental information. As a result, we found that the uncertainty in F{sub 1}{sup s}(t) due to the s(x) - anti s (x) distribution is rather large so that it dominates the model uncertainty at all values of the squared momentum transfer t. However, taking into account the uncertainties, the theoretical predictions of F{sub 1}{sup s}(t) are fully compatible with the estimate extracted from experiment. We concluded that the future accurate experimental data of the strange Dirac form factor might be used to put direct constraints on the strange content of the proton and reduce its uncertainty that has always been a challenge. (orig.)

33 CFR 157.170 - COW equipment: Removal.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false COW equipment: Removal. 157.170... Crude Oil Washing (COW) System on Tank Vessels Cow Operations § 157.170 COW equipment: Removal. (a) Whenever a deck mounted COW machine is removed from the tank, the master shall ensure that: (1) The supply...

Traffic disruption route Einstein near building 170

CERN Multimedia

A Lopez - TS/CE

2005-01-01

The TS/CE Group informs you that, for the duration of the work at Building 170, there may be some disruption to traffic on route Einstein in the vicinity of Building 170. The work is due to take place from the 14th to 18th February. For more information, please contact 165029. A. Lopez TS/CE

45 CFR 170.435 - ONC-ATCB application reconsideration.

Science.gov (United States)

2010-10-01

... Section 170.435 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.435 ONC...

25 CFR 170.149 - How do tribes identify transit needs?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false How do tribes identify transit needs? 170.149 Section 170... ROADS PROGRAM Indian Reservation Roads Program Policy and Eligibility Transit Facilities § 170.149 How do tribes identify transit needs? Tribes identify transit needs during the tribal transportation...

48 CFR 1402.170 - Acronyms.

Science.gov (United States)

2010-10-01

... AND TERMS Definitions 1402.170 Acronyms. A&EArchitect & Engineering ACMISAcquisition Career Management... CASCost Accounting Standards CASBCost Accounting Standards Board CBCACivilian Board of Contract Appeals...

25 CFR 170.148 - What is a tribal transit program?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false What is a tribal transit program? 170.148 Section 170.148... PROGRAM Indian Reservation Roads Program Policy and Eligibility Transit Facilities § 170.148 What is a tribal transit program? A tribal transit program is the planning, administration, acquisition, and...

The 170ms Response to Faces as Measured by MEG (M170 Is Consistently Altered in Congenital Prosopagnosia.

Directory of Open Access Journals (Sweden)

Andreas Lueschow

Full Text Available Modularity of face processing is still a controversial issue. Congenital prosopagnosia (cPA, a selective and lifelong impairment in familiar face recognition without evidence of an acquired cerebral lesion, offers a unique opportunity to support this fundamental hypothesis. However, in spite of the pronounced behavioural impairment, identification of a functionally relevant neural alteration in congenital prosopagnosia by electrophysiogical methods has not been achieved so far. Here we show that persons with congenital prosopagnosia can be distinguished as a group from unimpaired persons using magnetoencephalography. Early face-selective MEG-responses in the range of 140 to 200ms (the M170 showed prolonged latency and decreased amplitude whereas responses to another category (houses were indistinguishable between subjects with congenital prosopagnosia and unimpaired controls. Latency and amplitude of face-selective EEG responses (the N170 which were simultaneously recorded were statistically indistinguishable between subjects with cPA and healthy controls which resolves heterogeneous and partly conflicting results from existing studies. The complementary analysis of categorical differences (evoked activity to faces minus evoked activity to houses revealed that the early part of the 170ms response to faces is altered in subjects with cPA. This finding can be adequately explained in a common framework of holistic and part-based face processing. Whereas a significant brain-behaviour correlation of face recognition performance and the size of the M170 amplitude is found in controls a corresponding correlation is not seen in subjects with cPA. This indicates functional relevance of the alteration found for the 170ms response to faces in cPA and pinpoints the impairment of face processing to early perceptual stages.

25 CFR 170.121 - What is a cultural access road?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false What is a cultural access road? 170.121 Section 170.121 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN RESERVATION ROADS PROGRAM Indian Reservation Roads Program Policy and Eligibility Use of Irr and Cultural Access Roads § 170...

25 CFR 170.127 - What terms apply to access roads?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false What terms apply to access roads? 170.127 Section 170.127 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN RESERVATION ROADS PROGRAM Indian Reservation Roads Program Policy and Eligibility Irr Housing Access Roads § 170.127 What...

Direct Extraction of InP/GaAsSb/InP DHBT Equivalent-Circuit Elements From S-Parameters Measured at Cut-Off and Normal Bias Conditions

DEFF Research Database (Denmark)

Johansen, Tom Keinicke; Leblanc, Rémy; Poulain, Julien

2016-01-01

A unique direct parameter extraction method for the small-signal equivalent-circuit model of InP/GaAsSb/InP double heterojunction bipolar transistors (DHBTs) is presented. $S$-parameters measured at cut-off bias are used, at first, to extract the distribution factor $X_{0}$ for the base-collector......A unique direct parameter extraction method for the small-signal equivalent-circuit model of InP/GaAsSb/InP double heterojunction bipolar transistors (DHBTs) is presented. $S$-parameters measured at cut-off bias are used, at first, to extract the distribution factor $X_{0}$ for the base......-collector capacitance at zero collector current and the collector-to-emitter overlap capacitance $C_{ceo}$ present in InP DHBT devices. Low-frequency $S$-parameters measured at normal bias conditions then allows the extraction of the external access resistances $R_{bx}$, $R_{e}$, and $R_{cx}$ as well as the intrinsic...

Minority carrier diffusion length extraction in Cu2ZnSn(Se,S)4 solar cells

Science.gov (United States)

Gokmen, Tayfun; Gunawan, Oki; Mitzi, David B.

2013-09-01

We report measurement of minority carrier diffusion length (Ld) for high performance Cu2ZnSn(S,Se)4 (CZTSSe) solar cells in comparison with analogous Cu(In,Ga)(S,Se)2 (CIGSSe) devices. Our Ld extraction method involves performing systematic measurements of the internal quantum efficiency combined with separate capacitance-voltage measurement. This method also enables the measurement of the absorption coefficient of the absorber material as a function of wavelength in a finished device. The extracted values of Ld for CZTSSe samples are at least factor of 2 smaller than those for CIGSSe samples. Combined with minority carrier lifetime (τ) data measured by time-resolved photoluminescence, we deduce the minority carrier mobility (μe), which is also relatively low for the CZTSSe samples.

Identification of an algal carbon fixation-enhancing factor extracted from Paramecium bursaria.

Science.gov (United States)

Kato, Yutaka; Imamura, Nobutaka

2011-01-01

The green ciliate Paramecium bursaria contains several hundred symbiotic Chlorella species. We previously reported that symbiotic algal carbon fixation is enhanced by P. bursaria extracts and that the enhancing factor is a heat-stable, low-molecular-weight, water-soluble compound. To identify the factor, further experiments were carried out. The enhancing activity remained even when organic compounds in the extract were completely combusted at 700 degrees C, suggesting that the factor is an inorganic substance. Measurement of the major cations, K+, Ca2+, and Mg2+, by an electrode and titration of the extract resulted in concentrations of 0.90 mM, 0.55 mM, and 0.21 mM, respectively. To evaluate the effect of these cations, a mixture of the cations at the measured concentrations was prepared, and symbiotic algal carbon fixation was measured in the solution. The results demonstrated that the fixation was enhanced to the same extent as with the P. bursaria extract, and thus this mixture of K+, Ca2+, and Mg2+ was concluded to be the carbon fixation-enhancing factor. There was no effect of the cation mixture on free-living C. vulgaris. Comparison of the cation concentrations of nonsymbiotic and symbiotic Paramecium extracts revealed that the concentrations of K+ and Mg2+ in nonsymbiotic Paramecium extracts were too low to enhance symbiotic algal carbon fixation, suggesting that symbiotic P. bursaria provide suitable cation conditions for photosynthesis to its symbiotic Chlorella.

S. pombe CLASP needs dynein, not EB1 or CLIP170, to induce microtubule instability and slows polymerization rates at cell tips in a dynein-dependent manner

Science.gov (United States)

Grallert, Agnes; Beuter, Christoph; Craven, Rachel A.; Bagley, Steve; Wilks, Deepti; Fleig, Ursula; Hagan, Iain M.

2006-01-01

The Schizosaccharomyces pombe CLIP170-associated protein (CLASP) Peg1 was identified in a screen for mutants with spindle formation defects and a screen for molecules that antagonized EB1 function. The conditional peg1.1 mutant enabled us to identify key features of Peg1 function. First, Peg1 was required to form a spindle and astral microtubules, yet destabilized interphase microtubules. Second, Peg1 was required to slow the polymerization rate of interphase microtubules that establish end-on contact with the cortex at cell tips. Third, Peg1 antagonized the action of S. pombe CLIP170 (Tip1) and EB1 (Mal3). Fourth, although Peg1 resembled higher eukaryotic CLASPs by physically associating with both Mal3 and Tip1, neither Tip1 nor Mal3 was required for Peg1 to destabilize interphase microtubules or for it to associate with microtubules. Conversely, neither Mal3 nor Tip1 required Peg1 to associate with microtubules or cell tips. Consistently, while mal3.Δ and tip1.Δ disrupted linear growth, corrupting peg1 + did not. Fifth, peg1.1 phenotypes resembled those arising from deletion of the single heavy or both light chains of fission yeast dynein. Furthermore, all interphase phenotypes arising from peg1 + manipulation relied on dynein function. Thus, the impact of S. pombe CLASP on interphase microtubule behavior is more closely aligned to dynein than EB1 or CLIP170. PMID:16951255

Effects of hot water pre-extraction on surface properties of bagasse soda pulp.

Science.gov (United States)

Cordeiro, Nereida; Ashori, Alireza; Hamzeh, Yahya; Faria, Marisa

2013-03-01

In this work, the effects of hot water pre-extraction of depithed bagasse on the soda pulping and surface properties were studied. The conditions of hot water pre-extraction were: maximum temperature 170 °C, heat-up time 90 min, time at maximum temperature 10 min, and solid to liquor ratio (S:L) 1:8. Consequently, the pre-extracted and un-extracted bagasse chips were subjected to soda pulping at 160 °C for 1h with 11, 14 and 17% active alkali charge and an S:L of 1:5. The results showed that the hot water pre-extraction increased bagasse surface texture porosity by hemicellulose degradation. Therefore, the delignification was faster for pulping of pre-extracted samples. At a certain charge of alkali, pre-extracted samples showed higher screened yield and lower Kappa number. For instance, at 17% alkali charge, pre-extracted bagasse gave 11.3% higher pulp yield compared with the un-extracted ones. Inverse gas chromatography (IGC) results showed that the hot water pre-extraction changed the active sites on the bagasse surface, decreasing the dispersive energy and the basicity character, and affected the particle morphology. The pulping process decreased the hydrophobicity and the basicity of the bagasse surface. The surfaces of un-extracted and pre-extracted bagasse pulps had similar properties but different morphology. The pulps present higher surface area and permeability with more reactive capacity. Copyright © 2012 Elsevier B.V. All rights reserved.

Selectivity of N170 for visual words in the right hemisphere: Evidence from single-trial analysis.

Science.gov (United States)

Yang, Hang; Zhao, Jing; Gaspar, Carl M; Chen, Wei; Tan, Yufei; Weng, Xuchu

2017-08-01

Neuroimaging and neuropsychological studies have identified the involvement of the right posterior region in the processing of visual words. Interestingly, in contrast, ERP studies of the N170 typically demonstrate selectivity for words more strikingly over the left hemisphere. Why is right hemisphere selectivity for words during the N170 epoch typically not observed, despite the clear involvement of this region in word processing? One possibility is that amplitude differences measured on averaged ERPs in previous studies may have been obscured by variation in peak latency across trials. This study examined this possibility by using single-trial analysis. Results show that words evoked greater single-trial N170s than control stimuli in the right hemisphere. Additionally, we observed larger trial-to-trial variability on N170 peak latency for words as compared to control stimuli over the right hemisphere. Results demonstrate that, in contrast to much of the prior literature, the N170 can be selective to words over the right hemisphere. This discrepancy is explained in terms of variability in trial-to-trial peak latency for responses to words over the right hemisphere. © 2017 Society for Psychophysiological Research.

40 CFR 170.9 - Violations of this part.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Violations of this part. 170.9 Section... PROTECTION STANDARD General Provisions § 170.9 Violations of this part. (a) Under the Federal Insecticide... general sanitary hazards addressed by the OSHA Field Sanitation Standard, 29 CFR 1928.110, or other...

40 CFR 170.232 - Knowledge of labeling and site-specific information.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Knowledge of labeling and site-specific information. 170.232 Section 170.232 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS WORKER PROTECTION STANDARD Standard for Pesticide Handlers § 170.232 Knowledge...

45 CFR 170.445 - Complete EHR testing and certification.

Science.gov (United States)

2010-10-01

... Section 170.445 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.445...

Vector valued logarithmic residues and the extraction of elementary factors

NARCIS (Netherlands)

H. Bart (Harm); T. Ehrhardt; B. Silbermann

2007-01-01

textabstractAn analysis is presented of the circumstances under which, by the extraction of elementary factors, an analytic Banach algebra valued function can be transformed into one taking invertible values only. Elementary factors are generalizations of the simple scalar expressions λ – α, the

45 CFR 170.410 - Types of testing and certification.

Science.gov (United States)

2010-10-01

... Section 170.410 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.410 Types...

45 CFR 170.450 - EHR module testing and certification.

Science.gov (United States)

2010-10-01

... Section 170.450 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.450 EHR...

Effect of extraction method and orientin content on radio-protective effect of tulsi extracts

Energy Technology Data Exchange (ETDEWEB)

Tiwari, Mrinalini; Dwarakanath, B. S.; Agrawala, Paban K., E-mail: pkagrawal@gmail.com [Institute of Nuclear Medicine and Allied Sciences, Delhi (India); Murugan, R.; Parimelazhagan, T. [Department of Botany, Bharathiar University, Coimbatore (India); Uma Devi, P. [ARA-B-3SA, Plavilakonam,Trivandrum (India); Gota, V.; Sarin, R. K. [Advanced Centre for Treatment Research and Education in Cancer, Navi Mumbai (India)

2014-07-01

Extract of tulsi leaves (Ocimum sanctum) has been reported for its radioprotective efficacy. In our initial studies we observed significant variation in the survival of irradiated mice with different batches of tulsi extracts and therefore we employed different extraction methods on leaves collected during various seasons from different localities to study any variation in the radioprotective efficacy. Orientin, a component of tulsi extract, was considered a marker. Mice whole body survival (at 10 Gy lethal whole body irradiation) study and day 11 endo-CFU-s assay (at 5 Gy WBI) were performed employing 3 treatment schedules, 50 mg/kg or 25 mg/kg b.w (single injection, 30 min irradiation), and 10 mg/kgb.w (one injection per day for 5 day, last injection being 30 min before irradiation). Single dose of 25 mg/kg b.w (both aqueous and alcoholic) did not provide any significant survival benefit. The orientin concentrations in the extracts tested varied from 3.3 to 9.91 mg/g extract as studied by HPLC method. With a single administration (i.p) of 50 mg/kg, the aqueous extract from leaves of monsoon season had an orientin content of 9.91 mg/g extract and gave a survival of 60% with a CFU-s count of 37, while extract of leaf summer leaves had an orientin content of 4.15 mg/g extract and gave a survival of 50% with a CFU-s count of 11.6. At the same dose (50 mg/kg), the aqueous extract from the winter season had an orientin content of 3.30 mg/g extract and gave 25% survival with a CFU-s count of 19, while the ethanolic extract had an orientin content of 7.70 mg/g extract and gave a survival of 50% with a CFU-s count of 13. These observations suggest that different climatic factors, orientin content and the doses of administration are important factors regulating radioprotection afforded by different extracts of tulsi. (author)

Print-specific N170 involves multiple subcomponents for Japanese Hiragana.

Science.gov (United States)

Uno, Tomoki; Okumura, Yasuko; Kasai, Tetsuko

2017-05-22

Print-specific N170 in event-related potentials is generally considered to reflect relatively automatic processing for letter strings, which is crucial for fluent reading. However, our previous studies demonstrated that print-specific N170 for transparent Japanese Hiragana script consists of at least two subcomponents under rapid stimulus presentation: an attention-related left-lateralized N170 and a bilateral N170 associated with more automatic orthographic processes (Okumura, Kasai & Murohashi, 2014, 2015). The present study aimed to confirm the latter component by controlling presentation frequency of letters and nonlinguistic visual controls (i.e., symbols), but found a quite different pattern of results; an enhanced occipito-temporal positivity for words (80-120ms poststimulus) followed by the typical left-lateralized N170 and an enhanced parietal negativity for nonwords (150-200ms). These results should provide further insights into the interaction processes between attention and early stages of print processing. Copyright © 2017 Elsevier B.V. All rights reserved.

26 CFR 1.170A-12T - Valuation of a remainder interest in real property for contributions made after July 31, 1969...

Science.gov (United States)

2010-04-01

... depreciation factor. If the valuation of the remainder interest in depreciable property is dependent upon the... 26 Internal Revenue 3 2010-04-01 2010-04-01 false Valuation of a remainder interest in real property for contributions made after July 31, 1969 (temporary). 1.170A-12T Section 1.170A-12T Internal...

25 CFR 170.401 - What is BIA's role in transportation planning?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false What is BIA's role in transportation planning? 170.401... RESERVATION ROADS PROGRAM Planning, Design, and Construction of Indian Reservation Roads Program Facilities Transportation Planning § 170.401 What is BIA's role in transportation planning? Except as provided in § 170.402...

33 CFR 80.170 - Sandy Hook, NJ to Tom's River, NJ.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Sandy Hook, NJ to Tom's River, NJ. 80.170 Section 80.170 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Atlantic Coast § 80.170 Sandy Hook, NJ to Tom's River...

45 CFR 170.401 - Applicability.

Science.gov (United States)

2010-10-01

... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.401 Applicability...

Endoplasmic reticulum chaperone glucose regulated protein 170-Pokemon complexes elicit a robust antitumor immune response in vivo.

Science.gov (United States)

Yuan, Bangqing; Xian, Ronghua; Wu, Xianqu; Jing, Junjie; Chen, Kangning; Liu, Guojun; Zhou, Zhenhua

2012-07-01

Previous evidence suggested that the stress protein grp170 can function as a highly efficient molecular chaperone, binding to large protein substrates and acting as a potent vaccine against specific tumors when purified from the same tumor. In addition, Pokemon can be found in almost all malignant tumor cells and is regarded to be a promising candidate for the treatment of tumors. However, the potential of the grp170-Pokemon chaperone complex has not been well described. In the present study, the natural chaperone complex between grp170 and the Pokemon was formed by heat shock, and its immunogenicity was detected by ELISPOT and (51)Cr-release assays in vitro and by tumor bearing models in vivo. Our results demonstrated that the grp170-Pokemon chaperone complex could elicit T cell responses as determined by ELISPOT and (51)Cr-release assays. In addition, immunized C57BL/6 mice were challenged with subcutaneous (s.c.) injection of Lewis cancer cells to induce primary tumors. Treatment of mice with the grp170-Pokemon chaperone complex also significantly inhibited tumor growth and prolonged the life span of tumor-bearing mice. Our results indicated that the grp170-Pokemon chaperone complex might represent a powerful approach to tumor immunotherapy and have significant potential for clinical application. Copyright © 2012 Elsevier GmbH. All rights reserved.

Thulium-170-labeled microparticles for local radiotherapy: preliminary studies.

Science.gov (United States)

Polyak, Andras; Das, Tapas; Chakraborty, Sudipta; Kiraly, Reka; Dabasi, Gabriella; Joba, Robert Peter; Jakab, Csaba; Thuroczy, Julianna; Postenyi, Zita; Haasz, Veronika; Janoki, Gergely; Janoki, Gyozo A; Pillai, Maroor R A; Balogh, Lajos

2014-10-01

The present article describes the preparation, characterization, and biological evaluation of Thulium-170 ((170)Tm) [T1/2 = 128.4 days; Eβmax = 968 keV; Eγ = 84 keV (3.26%)] labeled tin oxide microparticles for its possible use in radiation synovectomy (RSV) of medium-sized joints. (170)Tm was produced by irradiation of natural thulium oxide target. 170Tm-labeled microparticles were synthesized with high yield and radionuclidic purity (> 99%) along with excellent in vitro stability by following a simple process. Particle sizes and morphology of the radiolabeled particles were examined by light microscope, dynamic light scattering, and transmission electron microscope and found to be of stable spherical morphology within the range of 1.4-3.2 μm. The preparation was injected into the knee joints of healthy Beagle dogs intraarticularly for biological studies. Serial whole-body and regional images were taken by single-photon-emission computed tomography (SPECT) and SPECT-CT cameras up to 9 months postadministration, which showed very low leakage (compound did not show any possible radiotoxicological effect. These preliminary studies showed that 170Tm-labeled microparticles could be a promising nontoxic and effective radiopharmaceutical for RSV applications or later local antitumor therapy.

Use of recombinant factor VII for tooth extractions in a patient with severe congenital factor VII deficiency: a case report.

Science.gov (United States)

Weinstock, Robert J; Onyejiuwa, Andrew; Shnayder, Garry; Clarkson, Earl I

2015-04-01

Patients with factor VII deficiency have an increased risk of prolonged perioperative hemorrhage. In this article, the authors present a case of severe factor VII deficiency in a patient who required tooth extraction. A 44-year-old woman with severe congenital factor VII deficiency sought care for a symptomatic, carious, and nonrestorable maxillary right second molar that required extraction. The authors obtained hematologic consultation, and the patient underwent the extraction under general anesthesia in the inpatient setting. Perioperative management included performing relevant laboratory studies, preoperative recombinant factor VII infusion, and postoperative intravenous aminocaproic acid administration. No hemorrhagic complications occurred throughout the perioperative course. The degree of factor VII deficiency correlates poorly with bleeding risk. Perioperative management is variable, requiring preoperative consultation with a hematologist. Copyright © 2015 American Dental Association. Published by Elsevier Inc. All rights reserved.

Test of the combined method for extracting spectroscopic factors in N =50 nuclei

Science.gov (United States)

Walter, David; Cizewski, J. A.; Baugher, T.; Ratkiewicz, A.; Pain, S. D.; Nunes, F. M.; Ahn, S.; Cerizza, G.; Jones, K. L.; Manning, B.; Thornsberry, C.

2017-09-01

The single-particle properties of nuclei near shell closures and r-process waiting points can be observed using single-nucleon transfer reactions with beams of rare isotopes. However, approximations have to be made about the final bound state to extract spectroscopic information. An approach to constrain the bound state potential has been proposed by Mukhamedzhanov and Nunes. At peripheral reaction energies ( 5 MeV/u), the ANC for the nucleus can be extracted, and is combined with the same reaction at higher energies ( 40 MeV/u). These combined measurements can constrain the shape of the bound state potential, and the spectroscopic factor can be reliably extracted. To test this method, the 86Kr(d , p) reaction was performed in inverse kinematics with a 35 MeV/u beam at the National Superconducting Cyclotron Laboratory (NSCL) with the ORRUBA and SIDAR arrays of silicon strip detectors coupled to the S800 spectrometer. Successful results supported the measurement of a radioactive ion beam of 84Se at 45 MeV/u at the NSCL to be measured at the end of 2017. Results from the 86Kr(d , p) measurement will be presented as well as preparations for the upcoming 84Se(d , p) measurement. This work is supported in part by the National Science Foundation and U.S. D.O.E.

45 CFR 170.402 - Definitions.

Science.gov (United States)

2010-10-01

... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.402 Definitions. For...

45 CFR 170.405 - Correspondence.

Science.gov (United States)

2010-10-01

... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.405 Correspondence. (a...

Potential of pomegranate fruit extract (Punica granatum Linn.) to increase vascular endothelial growth factor and platelet-derived growth factor expressions on the post-tooth extraction wound of Cavia cobaya.

Science.gov (United States)

Nirwana, Intan; Rachmadi, Priyawan; Rianti, Devi

2017-08-01

Pomegranates fruit extracts have several activities, among others, anti-inflammatory, antibacterial, and antioxidants that have the main content punicalagin and ellagic acid. Pomegranate has the ability of various therapies through different mechanisms. Vascular endothelial growth factor (VEGF) function was to form new blood vessels produced by various cells one of them was macrophages. Platelet-derived growth factor (PDGF) was a growth factor proven chemotactic, increased fibroblast proliferation and collagen matrix production. In addition, VEGF and PDGF synergize in their ability to vascularize tissues. The PDGF function was to stabilize and regulate maturation of new blood vessels. Activities of pomegranate fruit extract were observed by measuring the increased of VEGF and PDGF expression as a marker of wound healing process. To investigate the potential of pomegranate extracts on the tooth extraction wound to increase the expression of VEGF and PDGF on the 4 th day of wound healing process. This study used 12 Cavia cobaya , which were divided into two groups, namely, the provision of 3% sodium carboxymethyl cellulose and pomegranate extract. The 12 C. cobaya would be executed on the 4 th day, the lower jaw of experimental animals was taken, decalcified about 30 days. The expression of VEGF and PDGF was examined using immunohistochemical techniques. The differences of VEGF and PDGF expression were evaluated statistically using t-test. Statistically analysis showed that there were significant differences between control and treatment groups (p<0.05). Pomegranate fruit extract administration increased VEGF and PDGF expression on post-tooth extraction wound.

Mass extraction rates of radionuclides in fallout material from a 170-kt nuclear crater

Energy Technology Data Exchange (ETDEWEB)

Fleming, E H [Lawrence Radiation Laboratory, University of California, Livermore, CA (United States)

1969-07-01

The quantity k is defined as the fraction of a nuclide in the environment which must be ingested each day over a given time period to receive a maximum allowable dose, in accordance with the International Commission on Radiological Protection guidelines. Values of k were computed for radionuclides produced in a single cratering detonation using current design technology. A new concept, called the 'Mass Extraction Rate,' is presented. This concept is defined as the mass of earth material from which the entire quantity of the radionuclide must be extracted and ingested each day by some natural process over a given time interval, which results in a permissible dose. Mass Extraction Rate values are tabulated. A comparison is made between the Mass Extraction Rate and the specific activity methods. (author)

Mass extraction rates of radionuclides in fallout material from a 170-kt nuclear crater

International Nuclear Information System (INIS)

Fleming, E.H.

1969-01-01

The quantity k is defined as the fraction of a nuclide in the environment which must be ingested each day over a given time period to receive a maximum allowable dose, in accordance with the International Commission on Radiological Protection guidelines. Values of k were computed for radionuclides produced in a single cratering detonation using current design technology. A new concept, called the 'Mass Extraction Rate,' is presented. This concept is defined as the mass of earth material from which the entire quantity of the radionuclide must be extracted and ingested each day by some natural process over a given time interval, which results in a permissible dose. Mass Extraction Rate values are tabulated. A comparison is made between the Mass Extraction Rate and the specific activity methods. (author)

Glehnia littoralis Extract Promotes Neurogenesis in the Hippocampal Dentate Gyrus of the Adult Mouse through Increasing Expressions of Brain-Derived Neurotrophic Factor and Tropomyosin-Related Kinase B.

Science.gov (United States)

Park, Joon Ha; Shin, Bich Na; Ahn, Ji Hyeon; Cho, Jeong Hwi; Lee, Tae-Kyeong; Lee, Jae-Chul; Jeon, Yong Hwan; Kang, Il Jun; Yoo, Ki-Yeon; Hwang, In Koo; Lee, Choong Hyun; Noh, Yoo Hun; Kim, Sung-Su; Won, Moo-Ho; Kim, Jong Dai

2018-03-20

Glehnia littoralis has been used for traditional Asian medicine, which has diverse therapeutic activities. However, studies regarding neurogenic effects of G. littoralis have not yet been considered. Therefore, in this study, we examined effects of G. littoralis extract on cell proliferation, neuroblast differentiation, and the maturation of newborn neurons in the hippocampus of adult mice. A total of 39 male ICR mice (12 weeks old) were randomly assigned to vehicle-treated and 100 and 200 mg/kg G. littoralis extract-treated groups (n = 13 in each group). Vehicle and G. littoralis extract were orally administrated for 28 days. To examine neurogenic effects of G. littoralis extract, we performed immunohistochemistry for 5-bromo-2-deoxyuridine (BrdU, an indicator for cell proliferation) and doublecortin (DCX, an immature neuronal marker) and double immunofluorescence staining for BrdU and neuronal nuclear antigen (NeuN, a mature neuronal marker). In addition, we examined expressional changes of brain-derived neurotrophic factor (BDNF) and its major receptor tropomyosin-related kinase B (TrkB) using Western blotting analysis. Treatment with 200 mg/kg, not 100 mg/kg, significantly increased number of BrdU-immunoreactive ( + ) and DCX + cells (48.0 ± 3.1 and 72.0 ± 3.8 cells/section, respectively) in the subgranular zone (SGZ) of the dentate gyrus (DG) and BrdU + /NeuN + cells (17.0 ± 1.5 cells/section) in the granule cell layer as well as in the SGZ. In addition, protein levels of BDNF and TrkB (about 232% and 244% of the vehicle-treated group, respectively) were significantly increased in the DG of the mice treated with 200 mg/kg of G. littoralis extract. G. littoralis extract promots cell proliferation, neuroblast differentiation, and neuronal maturation in the hippocampal DG, and neurogenic effects might be closely related to increases of BDNF and TrkB proteins by G. littoralis extract treatment.

77 FR 30022 - U.S. Extractive Industries Transparency Initiative Stakeholder Assessment Public Listening...

Science.gov (United States)

2012-05-21

... DEPARTMENT OF THE INTERIOR [Docket No. ONRR-2012-0003] U.S. Extractive Industries Transparency... Extractive Industries Transparency Initiative Stakeholder Assessment and Multi-Stakeholder Group Options. In... in the Extractive Industries Transparency Initiative. EITI is a signature initiative of the U.S...

21 CFR 170.18 - Tolerances for related food additives.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Tolerances for related food additives. 170.18... (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) FOOD ADDITIVES General Provisions § 170.18 Tolerances for related food additives. (a) Food additives that cause similar or related pharmacological effects will be...

21 CFR 170.10 - Food additives in standardized foods.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Food additives in standardized foods. 170.10... (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) FOOD ADDITIVES General Provisions § 170.10 Food additives... the Act, which proposes the inclusion of a food additive in such definition and standard of identity...

29 CFR 4.170 - Furnishing fringe benefits or equivalents.

Science.gov (United States)

2010-07-01

... 29 Labor 1 2010-07-01 2010-07-01 true Furnishing fringe benefits or equivalents. 4.170 Section 4... Standards Compliance with Compensation Standards § 4.170 Furnishing fringe benefits or equivalents. (a) General. Fringe benefits required under the Act shall be furnished, separate from and in addition to the...

Inhibition of Steptococcus mutans biofilm formation by extracts of Tenacibaculum sp. 20J, a bacterium with wide-spectrum quorum quenching activity

OpenAIRE

Muras, Andrea; Mayer, Celia; Romero, Manuel; Camino, Tamara; Ferrer, Maria D.; Mira, Alex; Otero, Ana

2018-01-01

ABSTRACT Background: Previous studies have suggested the quorum sensing signal AI-2 as a potential target to prevent the biofilm formation by Streptococcus mutans, a pathogen involved in tooth decay. Objective: To obtain inhibition of biofilm formation by S. mutans by extracts obtained from the marine bacterium Tenacibaculum sp. 20J interfering with the AI-2 quorum sensing system. Design: The AI-2 inhibitory activity was tested with the biosensors Vibrio harveyi BB170 and JMH597. S. mutans AT...

41 CFR 102-41.170 - Is unclaimed personal property available for donation?

Science.gov (United States)

2010-07-01

... property available for donation? 102-41.170 Section 102-41.170 Public Contracts and Property Management... Personal Property § 102-41.170 Is unclaimed personal property available for donation? No, unclaimed personal property is not available for donation because reimbursement at fair market value is required. ...

21 CFR 170.50 - Glycine (aminoacetic acid) in food for human consumption.

Science.gov (United States)

2010-04-01

... consumption. 170.50 Section 170.50 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) FOOD ADDITIVES Specific Administrative Rulings and Decisions § 170.50 Glycine (aminoacetic acid) in food for human consumption. (a) Heretofore, the...

41 CFR 102-192.170 - What are GSA's responsibilities in mail management?

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What are GSA's responsibilities in mail management? 102-192.170 Section 102-192.170 Public Contracts and Property Management... PROGRAMS 192-MAIL MANAGEMENT GSA's Responsibilities and Services § 102-192.170 What are GSA's...

Inner bremsstrahlung accompanying beta decay of 170Tm

International Nuclear Information System (INIS)

Sanjeeviah, H.; Venkataramaiah, P.; Gundu Rao, K.S.

1980-01-01

The inner bremmsstrahlung (IB) spectrum accompanying beta decay of 170 Tm was measured using magnetic deflection technique. The raw spectrum was unfolded using the procedure of Liden and Starfelt. The unfolded IB spectrum was compared with the theories of Knipp and Uhlenbeck and Bloch; Lewis and Ford. Comparison was made with Ford and Martin theory in order to estimate the contribution of detour transitions to the IB spectrum of 170 Tm. (author)

The Idea Is Good, but…: Failure to Replicate Associations of Oxytocinergic Polymorphisms with Face-Inversion in the N170.

Directory of Open Access Journals (Sweden)

Aisha J L Munk

Full Text Available In event-related potentials, the N170 manifests itself especially in reaction to faces. In the healthy population, face-inversion leads to stronger negative amplitudes and prolonged latencies of the N170, effects not being present in patients with autism-spectrum-disorder (ASD. ASD has frequently been associated with differences in oxytocinergic neurotransmission. This ERP-study aimed to investigate the face-inversion effect in association with oxytocinergic candidate genes. It was expected that risk-allele-carriers of the oxytocin-receptor-gene-polymorphism (rs53576 and of CD38 (rs379863 responded similar to upright and inverted faces as persons with ASD. Additionally, reactions to different facial emotional expressions were studied. As there have been difficulties with replications of those molecular genetic association studies, we aimed to replicate our findings in a second study.Seventy-two male subjects in the first-, and seventy-eight young male subjects in the replication-study conducted a face-inversion-paradigm, while recording EEG. DNA was extracted from buccal cells.Results revealed stronger N170-amplitudes and longer latencies in reaction to inverted faces in comparison to upright ones. Furthermore, effects of emotion on N170 were evident. Those effects were present in the first and in the second study. Whereas we found molecular-genetic associations of oxytocinergic polymorphisms with the N170 in the first study, we failed to do so in the replication sample.Results indicate that a deeper theoretical understanding of this research-field is needed, in order to generate possible explanations for these findings. Results, furthermore, support the hypotheses that success of reproducibility is correlated with strength of lower original p-values and larger effect sizes in the original study.

Knowledge of Men and Women about Infertility Risk Factors

Directory of Open Access Journals (Sweden)

Amirreza Talaiekhozani

2016-10-01

Full Text Available With technological developments, creation of new industries and changing lifestyles, infertility risk factors (IRF increased. Therefore creation of suitable solutions in society is crucial for the prevention of infertility. Since prevention of infertility in a society is directly related to awareness about infertility, in the present study the awareness of people about infertility risk factors was assessed. In this study, a survey questionnaire containing 24 factors related to IRF was developed and 170 persons (62 men and 108 women from Fooladshahr, Najafabad and Mobarakeh participated and data were extracted from these questionnaires and were statistically analyzed. Our study showed that average infertility awareness for men and women is 38% and 49% respectively. Also overall awareness was 44%. Also results showed that women’s awareness about mobile radiation and fast foods is significantly higher than men. On the other hand men have significantly higher awareness about adverse effects of chlorine in swimming pool on fertility. Higher women awareness may be related to their higher sensitivity for fertility. Also, generally a higher level of awareness was observed relating to mobile, air pollution, stress, fast foods, smoking and alcohol. Women have a higher level of awareness about infertility risk factors. Higher awareness about some IRFs may be results from widespread media coverage.

48 CFR 229.170-2 - Policy.

Science.gov (United States)

2010-10-01

... acquisition of services; (3) Generally is implemented through letters of offer and acceptance, other country... DEFENSE GENERAL CONTRACTING REQUIREMENTS TAXES General 229.170-2 Policy. (a) By law, bilateral agreements...

Development of tablets containing semipurified extract of guaraná (Paullinia cupana

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Traudi Klein

2012-12-01

Full Text Available This study evaluated the technological feasibility of producing a semipurified extract of guaraná (Paullinia cupana Kunth, Sapindaceae in tablet form, using a direct-compression process. Maltodextrin and gum arabic were used to produce the extract microparticles, in order to protect the microparticles against such factors as temperature, oxidation, and humidity. Using pharmacopoeial methodologies, technological and physicochemistry tests (determination of residual moisture, of bulk and tapped density, Hausner ratio, compressibility and compactibility index, appearance, mean weight, hardness, friability, disintegration time, determination of EPA amount in tablets and in vitro release profile were conducted. The formulation containing 200 mg of microparticles, 170 mg microcrystalline cellulose, and 10 mg lactose gave the best results in terms of hardness (116 N, friabilility (0.28%, mean weight (0.3821 g, and disintegration time (25 min for a tablet designed for oral administration. The results met pharmacopoeial specifications, and the tablets are suitable for oral administration.

Seeing race: N170 responses to race and their relation to automatic racial attitudes and controlled processing.

Science.gov (United States)

Ofan, Renana H; Rubin, Nava; Amodio, David M

2011-10-01

We examined the relation between neural activity reflecting early face perception processes and automatic and controlled responses to race. Participants completed a sequential evaluative priming task, in which two-tone images of Black faces, White faces, and cars appeared as primes, followed by target words categorized as pleasant or unpleasant, while encephalography was recorded. Half of these participants were alerted that the task assessed racial prejudice and could reveal their personal bias ("alerted" condition). To assess face perception processes, the N170 component of the ERP was examined. For all participants, stronger automatic pro-White bias was associated with larger N170 amplitudes to Black than White faces. For participants in the alerted condition only, larger N170 amplitudes to Black versus White faces were also associated with less controlled processing on the word categorization task. These findings suggest that preexisting racial attitudes affect early face processing and that situational factors moderate the link between early face processing and behavior.

77 FR 26315 - U.S. Extractive Industries Transparency Initiative Stakeholder Assessment and Multi-Stakeholder...

Science.gov (United States)

2012-05-03

... DEPARTMENT OF THE INTERIOR [Docket No. ONRR-2012-0003] U.S. Extractive Industries Transparency... assessment as part of the U.S. Extractive Industries Transparency Initiative (USEITI) implementation process...' commitment to participate in the Extractive Industries Transparency Initiative. EITI is a signature...

25 CFR 170.407 - What happens to unobligated planning funds?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false What happens to unobligated planning funds? 170.407... RESERVATION ROADS PROGRAM Planning, Design, and Construction of Indian Reservation Roads Program Facilities Transportation Planning § 170.407 What happens to unobligated planning funds? Once all tribal governments...

77 FR 40893 - U.S. Extractive Industries Transparency Initiative Final Stakeholder Assessment and Multi...

Science.gov (United States)

2012-07-11

... DEPARTMENT OF THE INTERIOR [Docket No. ONRR-2012-0003] U.S. Extractive Industries Transparency... of the U.S. Extractive Industries Transparency Initiative (USEITI) implementation process. On July 11... United States' commitment to participate in the Extractive Industries Transparency Initiative. EITI is a...

Increased Dietary Intake of Saturated Fatty Acid Heptadecanoic Acid (C17:0 Associated with Decreasing Ferritin and Alleviated Metabolic Syndrome in Dolphins.

Directory of Open Access Journals (Sweden)

Stephanie K Venn-Watson

Full Text Available Similar to humans, bottlenose dolphins (Tursiops truncatus can develop metabolic syndrome and associated high ferritin. While fish and fish-based fatty acids may protect against metabolic syndrome in humans, findings have been inconsistent. To assess potential protective factors against metabolic syndrome related to fish diets, fatty acids were compared between two dolphin populations with higher (n = 30, Group A and lower (n = 19, Group B mean insulin (11 ± 12 and 2 ± 5 μIU/ml, respectively; P < 0.0001 and their dietary fish. In addition to higher insulin, triglycerides, and ferritin, Group A had lower percent serum heptadecanoic acid (C17:0 compared to Group B (0.3 ± 0.1 and 1.3 ± 0.4%, respectively; P < 0.0001. Using multivariate stepwise regression, higher percent serum C17:0, a saturated fat found in dairy fat, rye, and some fish, was an independent predictor of lower insulin in dolphins. Capelin, a common dietary fish for Group A, had no detectable C17:0, while pinfish and mullet, common in Group B's diet, had C17:0 (41 and 67 mg/100g, respectively. When a modified diet adding 25% pinfish and/or mullet was fed to six Group A dolphins over 24 weeks (increasing the average daily dietary C17:0 intake from 400 to 1700 mg, C17:0 serum levels increased, high ferritin decreased, and blood-based metabolic syndrome indices normalized toward reference levels. These effects were not found in four reference dolphins. Further, higher total serum C17:0 was an independent and linear predictor of lower ferritin in dolphins in Group B dolphins. Among off the shelf dairy products tested, butter had the highest C17:0 (423mg/100g; nonfat dairy products had no detectable C17:0. We hypothesize that humans' movement away from diets with potentially beneficial saturated fatty acid C17:0, including whole fat dairy products, could be a contributor to widespread low C17:0 levels, higher ferritin, and metabolic syndrome.

Extraction of the neutron electric form factor from measurements of inclusive double spin asymmetries

Science.gov (United States)

Sulkosky, V.; Jin, G.; Long, E.; Zhang, Y.-W.; Mihovilovic, M.; Kelleher, A.; Anderson, B.; Higinbotham, D. W.; Širca, S.; Allada, K.; Annand, J. R. M.; Averett, T.; Bertozzi, W.; Boeglin, W.; Bradshaw, P.; Camsonne, A.; Canan, M.; Cates, G. D.; Chen, C.; Chen, J.-P.; Chudakov, E.; De Leo, R.; Deng, X.; Deur, A.; Dutta, C.; El Fassi, L.; Flay, D.; Frullani, S.; Garibaldi, F.; Gao, H.; Gilad, S.; Gilman, R.; Glamazdin, O.; Golge, S.; Gomez, J.; Hansen, J.-O.; Holmstrom, T.; Huang, J.; Ibrahim, H.; de Jager, C. W.; Jensen, E.; Jiang, X.; Jones, M.; Kang, H.; Katich, J.; Khanal, H. P.; King, P.; Korsch, W.; LeRose, J.; Lindgren, R.; Lu, H.-J.; Luo, W.; Markowitz, P.; Meekins, D.; Meziane, M.; Michaels, R.; Moffit, B.; Monaghan, P.; Muangma, N.; Nanda, S.; Norum, B. E.; Pan, K.; Parno, D.; Piasetzky, E.; Posik, M.; Punjabi, V.; Puckett, A. J. R.; Qian, X.; Qiang, Y.; Qui, X.; Riordan, S.; Saha, A.; Sawatzky, B.; Shabestari, M.; Shahinyan, A.; Shoenrock, B.; John, J. St.; Subedi, R.; Tobias, W. A.; Tireman, W.; Urciuoli, G. M.; Wang, D.; Wang, K.; Wang, Y.; Watson, J.; Wojtsekhowski, B.; Ye, Z.; Zhan, X.; Zhang, Y.; Zheng, X.; Zhao, B.; Zhu, L.; Jefferson Lab Hall A Collaboration

2017-12-01

Background: Measurements of the neutron charge form factor, GEn, are challenging because the neutron has no net charge. In addition, measurements of the neutron form factors must use nuclear targets which require accurately accounting for nuclear effects. Extracting GEn with different targets and techniques provides an important test of our handling of these effects. Purpose: The goal of the measurement was to use an inclusive asymmetry measurement technique to extract the neutron charge form factor at a four-momentum transfer of 1 (GeV/c ) 2 . This technique has very different systematic uncertainties than traditional exclusive measurements and thus serves as an independent check of whether nuclear effects have been taken into account correctly. Method: The inclusive quasielastic reaction 3He ⃗(e ⃗,e') was measured at Jefferson Laboratory. The neutron electric form factor, GEn, was extracted at Q2=0.98 (GeV/c ) 2 from ratios of electron-polarization asymmetries measured for two orthogonal target spin orientations. This Q2 is high enough that the sensitivity to GEn is not overwhelmed by the neutron magnetic contribution, and yet low enough that explicit neutron detection is not required to suppress pion production. Results: The neutron electric form factor, GEn, was determined to be 0.0414 ±0.0077 (stat)±0.0022 (syst) , providing the first high-precision inclusive extraction of the neutron's charge form factor. Conclusions: The use of the inclusive quasielastic 3He ⃗(e ⃗,e') with a four-momentum transfer near 1 (GeV/c ) 2 has been used to provide a unique measurement of GEn. This new result provides a systematically independent validation of the exclusive extraction technique results and implies that the nuclear corrections are understood. This is contrary to the proton form factor where asymmetry and differential cross section measurements have been shown to have large systematic differences.

21 CFR 170.20 - General principles for evaluating the safety of food additives.

Science.gov (United States)

2010-04-01

... food additives. 170.20 Section 170.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) FOOD ADDITIVES Food Additive Safety § 170.20 General principles for evaluating the safety of food additives. (a) In reaching a...

Cow placenta extract promotes murine hair growth through enhancing the insulin - like growth factor-1

Directory of Open Access Journals (Sweden)

Dongliang Zhang

2011-01-01

Full Text Available Background: Hair loss is seen as an irreversible process. Most research concentrates on how to elongate the anagen, reduce the negative factors of obstructing hair growth and improve the hair number and size. Aim: In our experiment, we tried to prove that the cow placenta extract can promote hair growth by elongating hair shaft and increasing hair follicle number. Materials and Methods: Cow placenta extract (CPE, water and minoxidil applied separately on the back of depilated B57CL/6 mice for the case, negative and positive control respectively. We checked the proliferation of cells which are resident in hair sheath, and the expression of a few growth factors which stimulate hair growth. Results: Result shows that placenta extract more efficiently accelerates cell division and growth factor expression, by raising the insulin-like growth factor (IGF-1 mRNA and protein level to increase HF size and hair length. Conclusions: The extract is not a purified product; so, it is less effective than minoxidil, which is approved by the US FDA for the treatment of male pattern baldness. If refinement is done, the placenta extract would be a good candidate medicine for hair loss.

21 CFR 145.170 - Canned peaches.

Science.gov (United States)

2010-04-01

... CONSUMPTION CANNED FRUITS Requirements for Specific Standardized Canned Fruits § 145.170 Canned peaches. (a... by a support through which it can freely move upward or downward. The lower end of the rod is a plane...

45 CFR 170.425 - Application submission.

Science.gov (United States)

2010-10-01

... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.425 Application...

45 CFR 170.415 - Application prerequisite.

Science.gov (United States)

2010-10-01

... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.415 Application...

21 CFR 170.6 - Opinion letters on food additive status.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Opinion letters on food additive status. 170.6... (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) FOOD ADDITIVES General Provisions § 170.6 Opinion letters on food additive status. (a) Over the years the Food and Drug Administration has given informal...

33 CFR 209.170 - Violations of laws protecting navigable waters.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Violations of laws protecting navigable waters. 209.170 Section 209.170 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF... navigable waters. (a) [Reserved] (b) Injuries to Government works. Section 14 of the River and Harbor Act of...

Perceptual load manipulation reveals sensitivity of the face-selective N170 to attention.

Science.gov (United States)

Mohamed, Tarik N; Neumann, Markus F; Schweinberger, Stefan R

2009-05-27

It has been controversial whether the face-sensitive N170 is affected by selective attention. We manipulated attention sensu Lavie's perceptual load theory to short (200 ms) presentations of task-irrelevant unfamiliar faces or houses, while participants identified superimposed target letters 'X' versus 'N'. These targets were strings of either six identical (low load) or six different letters (high load). Under low load, we found a prominent face-selective N170 response. Under high load, however, we not only observed a dramatic reduction of the face N170 but also an unexpected enhancement of the house N170, such that face selectivity was almost completely lost. We conclude that the early stages of face processing indexed by the N170 strongly depend on selective attention.

Predictive factors for cardiovascular diseases in women from the city of Jataí, Goiás states

Directory of Open Access Journals (Sweden)

Célia Scapin Duarte

2017-03-01

Full Text Available This study aimed to identify prevalent diseases and to correlate predictive factors to cardiovascular diseases (CVDs in women older than 18 years of age living in Jataí-Goiás-Brazil. This is a cross-sectional, quantitative descriptive study carried out in the year 2015 with the evaluation of 255 women members of two Strategic Family Health Units. The research instrument used was a questionnaire with closed answer questions, whose results were analyzed by the SPSS Program - Statistical Package for the Social Sciences, version 17.0. The results show that changes in pressure levels found in this study correlate with marked obesity, anthropometric measurements and Body Mass Index (BMI above normal levels. The risk factors for prevalent CVD were alcoholism, physical inactivity, extensive work hours and smoking. These data reinforce the importance of the implementation of preventive actions to be adopted by multiprofessional health teams in the city of Jataí, since the life habits practiced by the participants contribute to the increase of modifiable risk factors for cardiovascular diseases (CVDs.

Search for chargino and neutralino production at $\\sqrt{s}$ = 170 and 172 GeV at LEP

CERN Document Server

Ackerstaff, K.; Allison, John; Altekamp, N.; Anderson, K.J.; Anderson, S.; Arcelli, S.; Asai, S.; Axen, D.; Azuelos, G.; Ball, A.H.; Barberio, E.; Barlow, Roger J.; Bartoldus, R.; Batley, J.R.; Baumann, S.; Bechtluft, J.; Beeston, C.; Behnke, T.; Bell, A.N.; Bell, Kenneth Watson; Bella, G.; Bentvelsen, S.; Bethke, S.; Biebel, O.; Biguzzi, A.; Bird, S.D.; Blobel, V.; Bloodworth, I.J.; Bloomer, J.E.; Bobinski, M.; Bock, P.; Bonacorsi, D.; Boutemeur, M.; Bouwens, B.T.; Braibant, S.; Brigliadori, L.; Brown, Robert M.; Burckhart, H.J.; Burgard, C.; Burgin, R.; Capiluppi, P.; Carnegie, R.K.; Carter, A.A.; Carter, J.R.; Chang, C.Y.; Charlton, David G.; Chrisman, D.; Clarke, P.E.L.; Cohen, I.; Conboy, J.E.; Cooke, O.C.; Cuffiani, M.; Dado, S.; Dallapiccola, C.; Dallavalle, G.Marco; Davies, R.; De Jong, S.; del Pozo, L.A.; Desch, K.; Dienes, B.; Dixit, M.S.; do Couto e Silva, E.; Doucet, M.; Duchovni, E.; Duckeck, G.; Duerdoth, I.P.; Eatough, D.; Edwards, J.E.G.; Estabrooks, P.G.; Evans, H.G.; Evans, M.; Fabbri, F.; Fanti, M.; Faust, A.A.; Fiedler, F.; Fierro, M.; Fischer, H.M.; Fleck, I.; Folman, R.; Fong, D.G.; Foucher, M.; Furtjes, A.; Futyan, D.I.; Gagnon, P.; Gary, J.W.; Gascon, J.; Gascon-Shotkin, S.M.; Geddes, N.I.; Geich-Gimbel, C.; Geralis, T.; Giacomelli, G.; Giacomelli, P.; Giacomelli, R.; Gibson, V.; Gibson, W.R.; Gingrich, D.M.; Glenzinski, D.; Goldberg, J.; Goodrick, M.J.; Gorn, W.; Grandi, C.; Gross, E.; Grunhaus, J.; Gruwe, M.; Hajdu, C.; Hanson, G.G.; Hansroul, M.; Hapke, M.; Hargrove, C.K.; Hart, P.A.; Hartmann, C.; Hauschild, M.; Hawkes, C.M.; Hawkings, R.; Hemingway, R.J.; Herndon, M.; Herten, G.; Heuer, R.D.; Hildreth, M.D.; Hill, J.C.; Hillier, S.J.; Hobson, P.R.; Homer, R.J.; Honma, A.K.; Horvath, D.; Hossain, K.R.; Howard, R.; Huntemeyer, P.; Hutchcroft, D.E.; Igo-Kemenes, P.; Imrie, D.C.; Ingram, M.R.; Ishii, K.; Jawahery, A.; Jeffreys, P.W.; Jeremie, H.; Jimack, M.; Joly, A.; Jones, C.R.; Jones, G.; Jones, M.; Jost, U.; Jovanovic, P.; Junk, T.R.; Karlen, D.; Kartvelishvili, V.; Kawagoe, K.; Kawamoto, T.; Kayal, P.I.; Keeler, R.K.; Kellogg, R.G.; Kennedy, B.W.; Kirk, J.; Klier, A.; Kluth, S.; Kobayashi, T.; Kobel, M.; Koetke, D.S.; Kokott, T.P.; Kolrep, M.; Komamiya, S.; Kress, T.; Krieger, P.; von Krogh, J.; Kyberd, P.; Lafferty, G.D.; Lahmann, R.; Lai, W.P.; Lanske, D.; Lauber, J.; Lautenschlager, S.R.; Layter, J.G.; Lazic, D.; Lee, A.M.; Lefebvre, E.; Lellouch, D.; Letts, J.; Levinson, L.; Lloyd, S.L.; Loebinger, F.K.; Long, G.D.; Losty, M.J.; Ludwig, J.; Macchiolo, A.; Macpherson, A.; Mannelli, M.; Marcellini, S.; Markus, C.; Martin, A.J.; Martin, J.P.; Martinez, G.; Mashimo, T.; Mattig, Peter; McDonald, W.John; McKenna, J.; Mckigney, E.A.; McMahon, T.J.; McPherson, R.A.; Meijers, F.; Menke, S.; Merritt, F.S.; Mes, H.; Meyer, J.; Michelini, A.; Mikenberg, G.; Miller, D.J.; Mincer, A.; Mir, R.; Mohr, W.; Montanari, A.; Mori, T.; Morii, M.; Muller, U.; Mihara, S.; Nagai, K.; Nakamura, I.; Neal, H.A.; Nellen, B.; Nisius, R.; O'Neale, S.W.; Oakham, F.G.; Odorici, F.; Ogren, H.O.; Oh, A.; Oldershaw, N.J.; Oreglia, M.J.; Orito, S.; Palinkas, J.; Pasztor, G.; Pater, J.R.; Patrick, G.N.; Patt, J.; Pearce, M.J.; Perez-Ochoa, R.; Petzold, S.; Pfeifenschneider, P.; Pilcher, J.E.; Pinfold, J.; Plane, David E.; Poffenberger, P.; Poli, B.; Posthaus, A.; Rees, D.L.; Rigby, D.; Robertson, S.; Robins, S.A.; Rodning, N.; Roney, J.M.; Rooke, A.; Ros, E.; Rossi, A.M.; Routenburg, P.; Rozen, Y.; Runge, K.; Runolfsson, O.; Ruppel, U.; Rust, D.R.; Rylko, R.; Sachs, K.; Saeki, T.; Sarkisian, E.K.G.; Sbarra, C.; Schaile, A.D.; Schaile, O.; Scharf, F.; Scharff-Hansen, P.; Schenk, P.; Schieck, J.; Schleper, P.; Schmitt, B.; Schmitt, S.; Schoning, A.; Schroder, Matthias; Schultz-Coulon, H.C.; Schumacher, M.; Schwick, C.; Scott, W.G.; Shears, T.G.; Shen, B.C.; Shepherd-Themistocleous, C.H.; Sherwood, P.; Siroli, G.P.; Sittler, A.; Skillman, A.; Skuja, A.; Smith, A.M.; Snow, G.A.; Sobie, R.; Soldner-Rembold, S.; Springer, Robert Wayne; Sproston, M.; Stephens, K.; Steuerer, J.; Stockhausen, B.; Stoll, K.; Strom, David M.; Szymanski, P.; Tafirout, R.; Talbot, S.D.; Tanaka, S.; Taras, P.; Tarem, S.; Teuscher, R.; Thiergen, M.; Thomson, M.A.; von Torne, E.; Towers, S.; Trigger, I.; Trocsanyi, Z.; Tsur, E.; Turcot, A.S.; Turner-Watson, M.F.; Utzat, P.; Van Kooten, Rick J.; Verzocchi, M.; Vikas, P.; Vokurka, E.H.; Voss, H.; Wackerle, F.; Wagner, A.; Ward, C.P.; Ward, D.R.; Watkins, P.M.; Watson, A.T.; Watson, N.K.; Wells, P.S.; Wermes, N.; White, J.S.; Wilkens, B.; Wilson, G.W.; Wilson, J.A.; Wolf, G.; Wyatt, T.R.; Yamashita, S.; Yekutieli, G.; Zacek, V.; Zer-Zion, D.

1998-01-01

A search for charginos and neutralinos, predicted by supersymmetric theories, has been performed using a data sample of 10.3 pb^-1 at centre-of-mass energies of sqrt(s) = 170 and 172 GeV with the OPAL detector at LEP. No evidence for these particles has been found. The results are combined with those from previous OPAL chargino and neutralino searches at lower energies to obtain limits. Exclusion regions at 95% C.L. of parameters of the Minimal Supersymmetric Standard Model are determined. Within this framework, for tan(beta) >= 1.0, lower mass limits are placed on the lightest chargino and the three lightest neutralinos. The 95% C.L. lower mass limit on the lightest chargino, assuming that it is heavier than the lightest neutralino by more than 10 GeV, is 84.5 GeV for the case of a large universal scalar mass (m_0 > ~1 TeV) and 65.7 GeV for the smallest m_0 compatible with current limits on the sneutrino and slepton masses. The lower limit on the lightest neutralino mass at 95% C.L. for tan(beta) >= 1.0 is 2...

26 CFR 1.170A-6 - Charitable contributions in trust.

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2010-04-01

... governing instrument of the trust or from local law that the trustee would be required to apportion the... 26 Internal Revenue 3 2010-04-01 2010-04-01 false Charitable contributions in trust. 1.170A-6...-6 Charitable contributions in trust. (a) In general. (1) No deduction is allowed under section 170...

45 CFR 2490.170 - Compliance procedures.

Science.gov (United States)

2010-10-01

... Public Welfare Regulations Relating to Public Welfare (Continued) JAMES MADISON MEMORIAL FELLOWSHIP... THE JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION § 2490.170 Compliance procedures. (a) Except as... for coordinating implementation of this section. Complaints may be sent to James Madison Memorial...

Adaptation of HAMMER computer code to CYBER 170/750 computer

International Nuclear Information System (INIS)

Pinheiro, A.M.B.S.; Nair, R.P.K.

1982-01-01

The adaptation of HAMMER computer code to CYBER 170/750 computer is presented. The HAMMER code calculates cell parameters by multigroup transport theory and reactor parameters by few group diffusion theory. The auxiliary programs, the carried out modifications and the use of HAMMER system adapted to CYBER 170/750 computer are described. (M.C.K.) [pt

45 CFR 170.420 - Application.

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2010-10-01

...-audit against all sections of ISO/IEC 17025:2005 (incorporated by reference in § 170.499), and the following: (i) A copy of the applicant's quality system document according to section 4.2.2 of ISO/IEC 17025... according to section 4.9.1 of ISO/IEC 17025:2005; and (iii) The qualifications of each of the applicant's...

Bronquiectasias: aspectos diagnósticos e terapêuticos Estudo de 170 pacientes Bronchiectasis: diagnostic and therapeutic features A study of 170 patients

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José da Silva Moreira

2003-10-01

Full Text Available INTRODUÇÃO: Bronquiectasias são freqüentemente encontradas na prática médica no Brasil, levando a significativa morbidez e comprometimento da qualidade de vida de seus portadores. OBJETIVOS: Analisar aspectos diagnósticos e terapêuticos em uma série de pacientes com bronquiectasias atendidos em um serviço de doenças pulmonares. MÉTODO: Sinais, sintomas, achados radiográficos e microbiológicos, e resultados terapêuticos foram estudados em 170 pacientes portadores de bronquiectasias hospitalizados no período de 1978 a 2001 - 62,4% do sexo feminino, 37,6% do masculino, com idade média de 37 anos, variando entre 12 e 88 anos. RESULTADOS: Antecedente de pneumonia na infância foi detectado em 52,5% dos pacientes, de tratamento tisiológico em 19,8%; 8,8% tinham asma brônquica, e dois tinham síndrome de Kartagener. Os sintomas mais comuns foram tosse (100%, expectoração (96% e estertores pulmonares (66%. As lesões eram unilaterais em 46,5% dos casos. Pneumococo, H. influenzae ou flora mista estiveram presentes em 85% das amostras de escarro examinadas. Os 170 pacientes receberam inicialmente tratamento clínico à base de antibióticos e fisioterapia respiratória; 88 deles (52% mais jovens, com lesões menores e boa reserva funcional foram submetidos à cirurgia de ressecção pulmonar (82 unilaterais e seis bilaterais. Ocorreram dois óbitos hospitalares entre os pacientes que receberam tratamento exclusivamente clínico. Os pacientes tratados cirurgicamente tiveram acentuada melhora dos sintomas, raramente necessitando ser reinternados. CONCLUSÕES: Os prolongados sintomas broncopulmonares foram permanentemente aliviados na maioria dos pacientes com bronquiectasias que puderam ir à cirurgia de ressecção pulmonar, diferentemente dos que seguiram com o tratamento clínico.BACKGROUND: Bronchiectasis is a frequently found disease in medical practice in Brazil leading to significant morbidity and decrease in quality of life of

Erratum to: Nuclear triaxiality in the A ∼ 160–170 mass region: the ...

Indian Academy of Sciences (India)

Erratum to: Nuclear triaxiality in the A ∼ 160–170 mass region: the story so far. S MUKHOPADHYAY1,∗ and W C MA2. 1Nuclear Physics Division, Bhabha Atomic Research Centre, Mumbai 400 085, India. 2Department of Physics, Mississippi State University, Mississippi State, Mississippi 39762, USA. ∗. Corresponding ...

17 CFR 230.170 - Prohibition of use of certain financial statements.

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2010-04-01

... financial statements. 230.170 Section 230.170 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... certain financial statements. Financial statements which purport to give effect to the receipt and.... The caption of any such financial statement shall clearly set forth the assumptions upon which such...

48 CFR 203.170 - Business practices.

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2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Business practices. 203..., DEPARTMENT OF DEFENSE GENERAL IMPROPER BUSINESS PRACTICES AND PERSONAL CONFLICTS OF INTEREST Safeguards 203.170 Business practices. To ensure the separation of functions for oversight, source selection...

Fetal macrosomia as a risk factor for shoulder dystocia during vacuum extraction.

Science.gov (United States)

Herzberg, Shmuel; Kabiri, Doron; Mordechai, Tzlil; Haj Yahya, Rani; Chill, Henry; Levitt, Lorinne; Amsalem, Hagai; Ezra, Yossef

2017-08-01

Vacuum extraction of a macrosomic fetus is considered a risk factor for shoulder dystocia (SD). We evaluated maternal and fetal outcomes following vacuum extraction of macrosomic infants. A retrospective cohort study conducted in two large teaching hospitals. All deliveries of macrosomic infants by vacuum extraction and vaginal delivery were compared. The primary outcome measure was SD. Secondary outcome measures were severe perineal lacerations and postpartum hemorrhage. For statistical analysis, we used McNemar's test and χ 2 or Fisher's exact tests. Odds ratios were analyzed via a logistic regression model. From 2003 to 2013, there were 6019 (5.45%) deliveries of macrosomic fetuses, and 230 (0.21%) were delivered by vacuum extraction. There were 23 (10%) and seven (3.04%) cases of SD in the study and control groups, respectively. The risk of SD was significantly higher in the study group (p > 0.05). We found a significant association between SD and vacuum delivery [p = 0.003; OR = 3.54 (95% CI: 1.49-8.42)]. The composite adverse neonatal outcome rate was 6.5% (15/230) and 1.7% (4/230) in the study and control groups, respectively (p = 0.009). Vacuum extraction of a macrosomic infant is a risk factor for shoulder dystocia but not for postpartum hemorrhage or severe vaginal tears.

Studies on the method of producing radiographic 170Tm source

International Nuclear Information System (INIS)

Maeda, Sho

1976-08-01

A method of producing radiographic 170 Tm source has been studied, including target preparation, neutron irradiation, handling of the irradiated target in the hot cell and source capsules. On the basis of the results, practical 170 Tm radiographic sources (29 -- 49Ci, with pellets 3mm in diameter and 3mm long) were produced in trial by neutron irradiation with the JMTR. (auth.)

Micro-electromembrane extraction using multiple free liquid membranes and acceptor solutions - Towards selective extractions of analytes based on their acid-base strength

Czech Academy of Sciences Publication Activity Database

Kubáň, Pavel; Seip, K. F.; Gjelstad, A.; Pedersen-Bjergaard, S.

2016-01-01

Roč. 943, NOV (2016), s. 64-73 ISSN 0003-2670 R&D Projects: GA ČR(CZ) GA16-09135S Institutional support: RVO:68081715 Keywords : multiple phase extraction * electromembrane extraction * plasma Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 4.950, year: 2016

Micro-electromembrane extraction using multiple free liquid membranes and acceptor solutions - Towards selective extractions of analytes based on their acid-base strength

Czech Academy of Sciences Publication Activity Database

Kubáň, Pavel; Seip, K. F.; Gjelstad, A.; Pedersen-Bjergaard, S.

2016-01-01

Roč. 943, NOV (2016), s. 64-73 ISSN 0003-2670 R&D Projects: GA ČR(CZ) GA16-09135S Institutional support: RVO:68081715 Keywords : multiple phase extraction * electromembrane extraction * plasma Subject RIV: CB - Analytical Chemistry , Separation Impact factor: 4.950, year: 2016

48 CFR 1837.170 - Pension portability.

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2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Pension portability. 1837... ADMINISTRATION SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING Service Contracts-General 1837.170 Pension portability. (a) It is NASA's policy not to require pension portability in service contracts. However, pension...

75 FR 40849 - Implementation of Question 10 of 25 CFR Part 170, Subpart C, Indian Reservation Roads Program

Science.gov (United States)

2010-07-14

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Implementation of Question 10 of 25 CFR Part 170, Subpart C, Indian Reservation Roads Program AGENCY: Bureau of Indian Affairs, Interior. [[Page... Distribution Factor (RNDF) formula for Indian Reservation Road (IRR) Program funds. The determination is...

EXPERIMENTAL STUDY OF FIRMWARE FOR INPUT AND EXTRACTION OF USER’S VOICE SIGNAL IN VOICE AUTHENTICATION SYSTEMS

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O. N. Faizulaieva

2014-09-01

Full Text Available Scientific task for improving the signal-to-noise ratio for user’s voice signal in computer systems and networks during the process of user’s voice authentication is considered. The object of study is the process of input and extraction of the voice signal of authentication system user in computer systems and networks. Methods and means for input and extraction of the voice signal on the background of external interference signals are investigated. Ways for quality improving of the user’s voice signal in systems of voice authentication are investigated experimentally. Firmware means for experimental unit of input and extraction of the user’s voice signal against external interference influence are considered. As modern computer means, including mobile, have two-channel audio card, two microphones are used in the voice signal input. The distance between sonic-wave sensors is 20 mm and it provides forming one direction pattern lobe of microphone array in a desired area of voice signal registration (from 100 Hz to 8 kHz. According to the results of experimental studies, the usage of directional properties of the proposed microphone array and space-time processing of the recorded signals with implementation of constant and adaptive weighting factors has made it possible to reduce considerably the influence of interference signals. The results of firmware experimental studies for input and extraction of the user’s voice signal against external interference influence are shown. The proposed solutions will give the possibility to improve the value of the signal/noise ratio of the useful signals recorded up to 20 dB under the influence of external interference signals in the frequency range from 4 to 8 kHz. The results may be useful to specialists working in the field of voice recognition and speaker discrimination.

25 CFR 170.400 - What is the purpose of transportation planning?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false What is the purpose of transportation planning? 170.400... RESERVATION ROADS PROGRAM Planning, Design, and Construction of Indian Reservation Roads Program Facilities Transportation Planning § 170.400 What is the purpose of transportation planning? The purpose of transportation...

Impact of head models in N170 component source imaging: results in control subjects and ADHD patients

International Nuclear Information System (INIS)

Beltrachini, L; Blenkmann, A; Ellenrieder, N von; Muravchik, C H; Petroni, A; Urquina, H; Manes, F; Ibáñez, A

2011-01-01

The major goal of evoked related potential studies arise in source localization techniques to identify the loci of neural activity that give rise to a particular voltage distribution measured on the surface of the scalp. In this paper we evaluate the effect of the head model adopted in order to estimate the N170 component source in attention deficit hyperactivity disorder (ADHD) patients and control subjects, considering faces and words stimuli. The standardized low resolution brain electromagnetic tomography algorithm (sLORETA) is used to compare between the three shell spherical head model and a fully realistic model based on the ICBM-152 atlas. We compare their variance on source estimation and analyze the impact on the N170 source localization. Results show that the often used three shell spherical model may lead to erroneous solutions, specially on ADHD patients, so its use is not recommended. Our results also suggest that N170 sources are mainly located in the right occipital fusiform gyrus for faces stimuli and in the left occipital fusiform gyrus for words stimuli, for both control subjects and ADHD patients. We also found a notable decrease on the N170 estimated source amplitude on ADHD patients, resulting in a plausible marker of the disease.

Impact of head models in N170 component source imaging: results in control subjects and ADHD patients

Science.gov (United States)

Beltrachini, L.; Blenkmann, A.; von Ellenrieder, N.; Petroni, A.; Urquina, H.; Manes, F.; Ibáñez, A.; Muravchik, C. H.

2011-12-01

The major goal of evoked related potential studies arise in source localization techniques to identify the loci of neural activity that give rise to a particular voltage distribution measured on the surface of the scalp. In this paper we evaluate the effect of the head model adopted in order to estimate the N170 component source in attention deficit hyperactivity disorder (ADHD) patients and control subjects, considering faces and words stimuli. The standardized low resolution brain electromagnetic tomography algorithm (sLORETA) is used to compare between the three shell spherical head model and a fully realistic model based on the ICBM-152 atlas. We compare their variance on source estimation and analyze the impact on the N170 source localization. Results show that the often used three shell spherical model may lead to erroneous solutions, specially on ADHD patients, so its use is not recommended. Our results also suggest that N170 sources are mainly located in the right occipital fusiform gyrus for faces stimuli and in the left occipital fusiform gyrus for words stimuli, for both control subjects and ADHD patients. We also found a notable decrease on the N170 estimated source amplitude on ADHD patients, resulting in a plausible marker of the disease.

Impact of head models in N170 component source imaging: results in control subjects and ADHD patients

Energy Technology Data Exchange (ETDEWEB)

Beltrachini, L; Blenkmann, A; Ellenrieder, N von; Muravchik, C H [Laboratory of Industrial Electronics, Control and Instrumentation (LEICI), National University of La Plata (Argentina); Petroni, A [Integrative Neuroscience Laboratory, Physics Department, University of Buenos Aires, Buenos Aires (Argentina); Urquina, H; Manes, F; Ibanez, A [Institute of Cognitive Neurology (INECO) and Institute of Neuroscience, Favaloro University, Buenos Aires (Argentina)

2011-12-23

The major goal of evoked related potential studies arise in source localization techniques to identify the loci of neural activity that give rise to a particular voltage distribution measured on the surface of the scalp. In this paper we evaluate the effect of the head model adopted in order to estimate the N170 component source in attention deficit hyperactivity disorder (ADHD) patients and control subjects, considering faces and words stimuli. The standardized low resolution brain electromagnetic tomography algorithm (sLORETA) is used to compare between the three shell spherical head model and a fully realistic model based on the ICBM-152 atlas. We compare their variance on source estimation and analyze the impact on the N170 source localization. Results show that the often used three shell spherical model may lead to erroneous solutions, specially on ADHD patients, so its use is not recommended. Our results also suggest that N170 sources are mainly located in the right occipital fusiform gyrus for faces stimuli and in the left occipital fusiform gyrus for words stimuli, for both control subjects and ADHD patients. We also found a notable decrease on the N170 estimated source amplitude on ADHD patients, resulting in a plausible marker of the disease.

25 CFR 170.811 - What happens if lack of funds results in inadequate maintenance?

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2010-04-01

... maintenance? 170.811 Section 170.811 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN RESERVATION ROADS PROGRAM BIA Road Maintenance § 170.811 What happens if lack of funds results in inadequate maintenance? If BIA determines that an IRR transportation facility is not being...

40 CFR 170.112 - Entry restrictions.

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2010-07-01

...-entry interval applies, including, but not limited to, soil, water, air, or surfaces of plants; and (2...-entry activity, the agricultural employer shall provide a decontamination site in accordance with § 170... running water for routine and emergency decontamination and mechanical devices that would reduce the...

Pressurized liquid extracts from Spirulina platensis microalga Determination of their antioxidant activity and preliminary analysis by micellar electrokinetic chromatography

OpenAIRE

Herrero, Miguel; Ibáñez, Elena; Señorans, F. Javier; Cifuentes, Alejandro

2004-01-01

In this work, different extracts from the microalga Spirulina platensis are obtained using pressurized liquid extraction (PLE) and four different solvents (hexane, light petroleum, ethanol andwater). Different extraction temperatures (115 and 170 ◦C) were tested using extraction times ranging from 9 to 15 min. The antioxidant activity of the different extracts is determined by means of an in vitro assay using a free radical method. Moreover, a new and fast method is developed using m...

N170 Tuning in Chinese: Logographic Characters and Phonetic Pinyin Script

Science.gov (United States)

Qin, Rui; Maurits, Natasha; Maassen, Ben

2016-01-01

In alphabetic languages, print consistently elicits enhanced, left-lateralized N170 responses in the event-related potential compared to control stimuli. In the current study, we adopted a cross-linguistic design to investigate N170 tuning to logographic Chinese and to "pinyin," an auxiliary phonetic system in Chinese. The results…

25 CFR 170.403 - What IRR Program funds can be used for transportation planning?

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2010-04-01

... Program Facilities Transportation Planning § 170.403 What IRR Program funds can be used for transportation... 25 Indians 1 2010-04-01 2010-04-01 false What IRR Program funds can be used for transportation planning? 170.403 Section 170.403 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND...

25 CFR 170.410 - What is the purpose of tribal long-range transportation planning?

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2010-04-01

... Program Facilities Long-Range Transportation Planning § 170.410 What is the purpose of tribal long-range... 25 Indians 1 2010-04-01 2010-04-01 false What is the purpose of tribal long-range transportation planning? 170.410 Section 170.410 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND...

45 CFR 170.423 - Principles of proper conduct for ONC-ATCBs.

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2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Principles of proper conduct for ONC-ATCBs. 170... § 170.423 Principles of proper conduct for ONC-ATCBs. An ONC-ATCB shall: (a) Operate its certification... EHR Module developer conspicuously include the following text on its Web site and in all marketing...

Factores de riesgo psicosocial y estrés percibido en trabajadores de una empresa eléctrica en Chile

Directory of Open Access Journals (Sweden)

Marjory Güilgüiruca Retamal

2015-03-01

Full Text Available Objetivos: El objetivo de esta investigación fue determinar la correlación entre riesgos psicosociales laborales y estrés percibido en trabajadores de una empresa del rubro eléctrico en Chile Material y Métodos: Se diseñó un estudio descriptivo, de alcance asociativo y de corte transversal, en el cual participaron 292 trabajadores. Se aplicó el instrumento SUSESO ISTAS-21, versión corta de la Superintendencia de Seguridad Social (SUSESO del Gobierno de Chile y la Escala de Estrés Percibido validada para población chilena. El análisis estadístico se realizó con el programa SPSS versión 17.0. Resultados: Los resultados indican que todos los factores de riesgos psicosociales estudiados presentan asociaciones estadísticamente significativas con estrés percibido. Destacan las relaciones de apoyo social y exigencias psicológicas con estrés percibido, así como la relación entre género y doble presencia, antigüedad laboral y trabajo activo, sistema de turno y compensaciones. Conclusiones: Los trabajadores evaluados manifiestan que en la medida que aumenta la percepción de riesgo de los factores psicosociales del trabajo, también aumentan sus niveles de estrés percibido con aspectos del contenido y organización del trabajo.

21 CFR 158.170 - Frozen peas.

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2010-04-01

... CONSUMPTION FROZEN VEGETABLES Requirements for Specific Standardized Frozen Vegetables § 158.170 Frozen peas... two or more, of the following safe and suitable optional ingredients: (i) Natural and artificial... “early June” shall precede or follow the name in the case of smooth-skin or substantially smooth-skin...

45 CFR 170.499 - Incorporation by reference.

Science.gov (United States)

2010-10-01

..., Switzerland, telephone +41-22-749-01-11, http://www.iso.org. (1) ISO/IEC 17025 General Requirements for the... and § 170.423. (2) ISO/IEC GUIDE 65 General Requirements for Bodies Operating Product Certification...

Astrophysical S factor for 13C(p,γ)14N and asymptotic normalization coefficients

International Nuclear Information System (INIS)

Mukhamedzhanov, A.M.; Azhari, A.; Gagliardi, C.A.; Sattarov, A.; Tang, X.; Trache, L.; Tribble, R.E.; Burjan, V.; Kroha, V.

2002-01-01

We reanalyze the 13 C(p,γ) 14 N radiative capture reaction within the R-matrix approach. The low-energy astrophysical S factor has important contributions from both resonant and onresonant captures. The normalization of the nonresonant component of the transition to a particular 14 N bound state is expressed in terms of the asymptotic normalization coefficient (ANC). In the analysis we use the experimental ANC's inferred from the 13 C( 14 N, 13 C) 14 N and 13 C( 3 He,d) 14 N reactions. The fits of the calculated S factors to the experimental data are sensitive to the ANC values and are used to test the extracted ANC's. We find that for transitions to all the states in 14 N, except the third excited state, the ANC's determined from the transfer reactions provide the best fit. The astrophysical factor we obtain, S(0)=7.7±1.1 keV b, is in excellent agreement with previous results

25 CFR 170.801 - What is the BIA Road Maintenance Program?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false What is the BIA Road Maintenance Program? 170.801 Section... ROADS PROGRAM BIA Road Maintenance § 170.801 What is the BIA Road Maintenance Program? The BIA Road... subpart contains a list of activities that are eligible for funding under the BIA road maintenance program. ...

Simultaneous Extraction and Depolymerization of Fucoidan from Sargassum muticum in Aqueous Media

Directory of Open Access Journals (Sweden)

Elena M. Balboa

2013-11-01

Full Text Available The biomass components of the invasive seaweed Sargassum muticum were fractionated to allow their separate valorization. S. muticum (Sm and the solid residue remaining after alginate extraction of this seaweed (AESm were processed with hot, compressed water (hydrothermal processing to assess the effects of temperature on fucoidan solubilization. Fucose-containing oligosaccharides were identified as reaction products. Operating under optimal conditions (170 °C, up to 62 and 85 wt% of the dry mass of Sm and AESm were solubilized, respectively. The reaction media were subjected to precipitation, nanofiltration and freeze-drying. The dried products contained 50% and 85% of the fucoidan present in Sm and AESm, respectively; together with other components such as phenolics and inorganic components. The saccharidic fraction, accounting for up to 35% of the dried extracts, contained fucose as the main sugar, and also galactose, xylose, glucose and mannose. The concentrates were characterized for antioxidant activity using the TEAC assay.

Risk factors for recurrent symptomatic pigmented biliary stones after percutaneous transhepatic biliary extraction.

Science.gov (United States)

Kim, Dong Won; Lee, Sang Yun; Cho, Jin-Han; Kang, Myong Jin; Noh, Myung Hwan; Park, Byeong-Ho

2010-07-01

To evaluate risk factors for the recurrence of biliary stones after a percutaneous transhepatic biliary stone extraction. The procedures were performed on 339 patients between July 2004 and December 2008 (54 months). Medical records and images were retrospectively reviewed for 135 patients (mean age, 66.4 years; 83 men and 52 women) who had undergone follow-up for a mean of 13.2 months (range, 3-37 months). To evaluate risk factors for the recurrence of biliary stones, variables were evaluated with univariate and multivariate analyses. Variables included sex, age, stone location, number of stones, stone size, presence of a peripapillary diverticulum, application of antegrade sphincteroplasty, presence of a biliary stricture, largest biliary diameter before the procedure, and gallbladder status. Thirty-three of the 135 patients (24%) had recurrent symptomatic biliary stones and underwent an additional extraction. The mean time to recurrence was 17.2 months +/- 8.7. Univariate analysis of risk factors for recurrence of biliary stones demonstrated that location, number of stones, stone size, application of antegrade sphincteroplasty, presence of a biliary stricture, and biliary diameter were significant factors (P or =6; relative risk, 64.8; 95% confidence interval: 5.8, 717.6) and stone size (> or =14 mm; relative risk, 3.8; 95% confidence interval: 1.138, 13.231) were determined to be significant risk factors. The independent risk factors for recurrence of symptomatic biliary stones after percutaneous transhepatic biliary stone extraction were a stone size of at least 14 mm and the presence of at least six stones. Copyright 2010 SIR. Published by Elsevier Inc. All rights reserved.

Modeling a Hypothetical 170Tm Source for Brachytherapy Applications

International Nuclear Information System (INIS)

Enger, Shirin A.; D'Amours, Michel; Beaulieu, Luc

2011-01-01

Purpose: To perform absorbed dose calculations based on Monte Carlo simulations for a hypothetical 170 Tm source and to investigate the influence of encapsulating material on the energy spectrum of the emitted electrons and photons. Methods: GEANT4 Monte Carlo code version 9.2 patch 2 was used to simulate the decay process of 170 Tm and to calculate the absorbed dose distribution using the GEANT4 Penelope physics models. A hypothetical 170 Tm source based on the Flexisource brachytherapy design with the active core set as a pure thulium cylinder (length 3.5 mm and diameter 0.6 mm) and different cylindrical source encapsulations (length 5 mm and thickness 0.125 mm) constructed of titanium, stainless-steel, gold, or platinum were simulated. The radial dose function for the line source approximation was calculated following the TG-43U1 formalism for the stainless-steel encapsulation. Results: For the titanium and stainless-steel encapsulation, 94% of the total bremsstrahlung is produced inside the core, 4.8 and 5.5% in titanium and stainless-steel capsules, respectively, and less than 1% in water. For the gold capsule, 85% is produced inside the core, 14.2% inside the gold capsule, and a negligible amount ( 170 Tm source is primarily a bremsstrahlung source, with the majority of bremsstrahlung photons being generated in the source core and experiencing little attenuation in the source encapsulation. Electrons are efficiently absorbed by the gold and platinum encapsulations. However, for the stainless-steel capsule (or other lower Z encapsulations) electrons will escape. The dose from these electrons is dominant over the photon dose in the first few millimeter but is not taken into account by current standard treatment planning systems. The total energy spectrum of photons emerging from the source depends on the encapsulation composition and results in mean photon energies well above 100 keV. This is higher than the main gamma-ray energy peak at 84 keV. Based on our

Continuum limit of the leading order HQET form factor in B{sub s}→Klν decays

Energy Technology Data Exchange (ETDEWEB)

Bahr, Felix; Banerjee, Debasish; Koren, Mateusz; Simma, Hubert; Sommer, Rainer [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Bernardoni, Fabio [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Technische Univ. Dresden (Germany). Medizinische Fakultaet ' ' Carl Gustav Carus' ' ; Joseph, Anosh [Cambridge Univ. (United Kingdom). Dept. of Applied Mathematics and Theoretical Physics (DAMTP); Collaboration: ALPHA Collaboration

2016-01-15

We discuss the computation of form factors for semi-leptonic decays of B-, B{sub s}- mesons in lattice QCD. Considering in particular the example of the static B{sub s} form factors we demonstrate that after non-perturbative renormalization the continuum limit can be taken with confidence. The resulting precision is of interest for extractions of V{sub ub}. The size of the corrections of order 1/m{sub b} is just estimated at present but it is expected that their inclusion does not pose significant difficulties.

45 CFR 170.440 - ONC-ATCB status.

Science.gov (United States)

2010-10-01

... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.440 ONC-ATCB status...

45 CFR 170.400 - Basis and scope.

Science.gov (United States)

2010-10-01

... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.400 Basis and scope...

45 CFR 170.430 - Review of application.

Science.gov (United States)

2010-10-01

... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.430 Review of...

Huaier Aqueous Extract Induces Hepatocellular Carcinoma Cells Arrest in S Phase via JNK Signaling Pathway

Directory of Open Access Journals (Sweden)

Chengshuo Zhang

2015-01-01

Full Text Available Huaier aqueous extract, the main active constituent of Huaier proteoglycan, has antihepatocarcinoma activity in experimental and clinical settings. However, the potential and associated antihepatoma mechanisms of Huaier extract are not yet fully understood. Therefore, in this study, we aimed to elucidate the inhibitory proliferation effect of Huaier extract on apoptosis and cycle of HepG2 and Bel-7402 cells. Our data demonstrated that incubation with Huaier extract resulted in a marked decrease in cell viability dose-dependently. Flow cytometric analysis showed that a 48 h treatment of Huaier extract caused cell apoptosis. Typical apoptotic nucleus alterations were observed with fluorescence microscope after Hoechst staining. Immunoblot analysis further demonstrated that Huaier extract activated caspase 3 and PARP. Additionally, Huaier extract inhibited the activity of p-ERK, p-p38, and p-JNK in terms of MAPK. Furthermore, Huaier extract induced HCC cells arrest in S phase and decreased the cycle related protein expression of β-catenin and cyclin D1. Studies with JNK specific inhibitor, SP600125, showed that Huaier extract induced S phase arrest and decreased β-catenin and cyclin D1 expression via JNK signaling pathway. In conclusion, we verify that Huaier extract causes cell apoptosis and induces hepatocellular carcinoma cells arrest in S phase via JNK pathway, which advances our understanding on the molecular mechanisms of Huaier extract in hepatocarcinoma management.

At PS170 (APPLE)

CERN Multimedia

CERN PhotoLab

1983-01-01

APPLE stands for Antiproton-Proton to Pair of LEptons (an acronym of the ancestor experiment PAPLEP), the PS170 experiment setup at LEAR to study e+e-pair production in antiproton-proton annihilation by Padova-(CEN) Saclay- Torino Collaboration. It consisted of a liquid hydrogen target surrounded by several layers of proportional chambers in the vertical field of a C-magnet (this photo), a gas Cerenkov counter, wire chambers, hodoscopes, and an electromagnetic calorimeter (see photo 8302539X, 8302540X). See also photo 8301539X for the setup assembly at an early stage.

Experimental study of a 1 MW, 170 GHz gyrotron oscillator

Science.gov (United States)

Kimura, Takuji

A detailed experimental study is presented of a 1 MW, 170 GHz gyrotron oscillator whose design is consistent with the ECH requirements of the International Thermonuclear Experimental Reactor (ITER) for bulk heating and current drive. This work is the first to demonstrate that megawatt power level at 170 GHz can be achieved in a gyrotron with high efficiency for plasma heating applications. Maximum output power of 1.5 MW is obtained at 170.1 GHz in 85 kV, 50A operation for an efficiency of 35%. Although the experiment at MIT is conducted with short pulses (3 μs), the gyrotron is designed to be suitable for development by industry for continuous wave operation. The peak ohmic loss on the cavity wall for 1 MW of output power is calculated to be 2.3 kW/cm2, which can be handled using present cooling technology. Mode competition problems in a highly over-moded cavity are studied to maximize the efficiency. Various aspects of electron gun design are examined to obtain high quality electron beams with very low velocity spread. A triode magnetron injection gun is designed using the EGUN simulation code. A total perpendicular velocity spread of less than 8% is realized by designing a low- sensitivity, non-adiabatic gun. The RF power is generated in a short tapered cavity with an iris step. The operating mode is the TE28,8,1 mode. A mode converter is designed to convert the RF output to a Gaussian beam. Power and efficiency are measured in the design TE28,8,1 mode at 170.1 GHz as well as the TE27,8,1 mode at 166.6 GHz and TE29,8,1 mode at 173.5 GHz. Efficiencies between 34%-36% are consistently obtained over a wide range of operating parameters. These efficiencies agree with the highest values predicted by the multimode simulations. The startup scenario is investigated and observed to agree with the linear theory. The measured beam velocity ratio is consistent with EGUN simulation. Interception of reflected beam by the mod-anode is measured as a function of velocity ratio

Analysis of potential dynamic concealed factors in the difficulty of lower third molar extraction.

Science.gov (United States)

Singh, P; Ajmera, D-H; Xiao, S-S; Yang, X-Z; Liu, X; Peng, B

2016-11-01

The purpose of this study was to identify potential concealed variables associated with the difficulty of lower third molar (M3) extractions. To address the research purpose, we implemented a prospective study and enrolled a sample of subjects presenting for M3 removal. Predictor variables were categorized into Group-I and Group-II, based on predetermined criteria. The primary outcome variable was the difficulty of extraction, measured as extraction time. Appropriate univariate and multivariate statistics were computed using ordinal logistic regression. The sample comprised of 1235 subjects with a mean age of 29.49 +/- 8.92 years in Group-I and 26.20 +/- 11.55 years in Group-II subjects. The mean operating time per M3 extraction was 21.24 +/- 12.80 and 20.24 +/- 12.50 minutes for Group-I and Group-II subjects respectively. Three linear parameters including B-M2 height (distance between imaginary point B on the inferior border of mandibular body, and M2), lingual cortical thickness, bone density and one angular parameter including Rc-Cs angle (angle between ramus curvature and curve of spee), in addition to patient's age, profile type, facial type, cant of occlusal plane, and decreased overbite, were found to be statistically associated ( p < or = 0.05) with extraction difficulty under regression models. In conclusion, our study indicates that the difficulty of lower M3 extractions is possibly governed by morphological and biomechanical factors with substantial influence of myofunctional factors. Preoperative evaluation of dynamic concealed factors may not only help in envisaging the difficulty and planning of surgical approach but might also help in better time management in clinical practice.

12 CFR 410.170 - Compliance procedures.

Science.gov (United States)

2010-01-01

... Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY EXPORT-IMPORT BANK OF THE UNITED STATES § 410.170.... Complaints may be sent to General Counsel, Export-Import Bank of the United States, 811 Vermont Avenue, NW...

Solvent extraction of rare earth nitrates by Versatic Acid 911

Energy Technology Data Exchange (ETDEWEB)

Kazuoka, K; Tanabe, T; Kondo, Y [Kyoto Univ. (Japan)

1975-07-01

The extraction equilibria of cerous, terbium and yttrium nitrates into Versatic Acid 911 were studied. The organic phase was diluted with benzene, and the ionic strength of the aqueous solutions was maintained at unity by adding NaNO/sub 3/. Radioactive isotopes of these elements were used as the tracer. The compositions of the extracted species were CeR/sub 3/.4RH.H/sub 2/O, TbR/sub 3/.4RH.H/sub 2/O and YR/sub 3/.4RH.H/sub 2/o, and the apparent equilibrium constants of extraction were 9.14x10/sup -15/, 3.90x10/sup -14/ and 1.70x10/sup -14/, respectively.

Micro-electromembrane extraction across free liquid membranes. Extractions of basic drugs from undiluted biological samples

Czech Academy of Sciences Publication Activity Database

Kubáň, Pavel; Boček, Petr

2014-01-01

Roč. 1337, Apr (2014), s. 32-39 ISSN 0021-9673 R&D Projects: GA ČR(CZ) GA13-05762S Institutional support: RVO:68081715 Keywords : micro-electromembrane extraction * free liquid membranes * biological samples Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 4.169, year: 2014

Is the N170 face specific? Controversy, context, and theory

Directory of Open Access Journals (Sweden)

Brian D. Earp

2013-04-01

Full Text Available In cognitive science, there is an ongoing debate about the architecture of the mind: does it consist of a number of mental “organs” each managing a different function in isolation, or is it more of general processor, adaptable to a wide range of tasks? One corner of this debate has centered on face processing. This is because face-perception is crucial to normal human functioning and some evidence shows that faces may be processed by the brain in a privileged way compared to other types of stimuli. For example, in EEG brain recordings, the N170 is a characteristic signal that occurs after a participant is exposed to an image of a face, but it is much less pronounced when other stimuli are shown. More than 15 years of research on the “N170 face effect” have yielded the standard view that the N170 is at the very least face-sensitive, and possibly even face-specific, that is, indexing modular processes tied exclusively to facial geometries. The specificity claim is clearly stronger, and hence subject to significant controversy; while the more conservative “sensitivity” claim had been regarded (until recently as effectively settled. Nevertheless, Thierry and colleagues, in a contentious 2007 article, sought to undermine even this “conservative” consensus: they argued that the apparent face-responsiveness of the N170 in prior research was due to systematic flaws in experimental design. Fiery debate has followed. In this review, we put the debate in its historical and philosophical context, and try to spell out some of the theoretical and logical assumptions that underlie the claims of the competing camps. We then show that the best available evidence counts, at least partially, against the Thierry et al. construal of the N170. Accordingly, it would be premature to abandon the “conservative” account of the N170, according to which it is – minimally – responsive to faces. We conclude by returning to the more controversial claim

Development of a 170Tm source for mercury monitoring studies in humans using XRF

International Nuclear Information System (INIS)

Timmaraju, K. Phanisree; Fajurally, Bibi Najah; Armstrong, Andrea F.; Chettle, David R.

2016-01-01

The goals of the present study were to develop a 170 Tm radioisotope and generate a K XRF spectrum of mercury. Thulium foil and thulium oxide powder were both tested for impurities and the latter was found to be a better prospect for further studies. The 170 Tm radioisotope was developed from thulium oxide powder following the method of disolution and absorption. A suitable source holder and collimator were also designed based on Monte Carlo simulations. Using the radioisotope thus developed, a mercury XRF spectrum was successfully generated. - Highlights: • We tested the purity of thulium samples by XRF and NAA techniques. • Developed a procedure to generate Tm-170 isotope out of thulium oxide powder. • Designed a collimator and source holder • Generated XRF spectrum of mercury using the Tm-170 isotope. • Compared the highlights in mercury spectra from Tm-170 and Cd-109 isotopes.

25 CFR 170.120 - What restrictions apply to the use of an Indian Reservation Road?

Science.gov (United States)

2010-04-01

... Reservation Road? 170.120 Section 170.120 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN RESERVATION ROADS PROGRAM Indian Reservation Roads Program Policy and Eligibility Use of Irr and Cultural Access Roads § 170.120 What restrictions apply to the use of an Indian...

Factors influencing the Zn and Mn extraction from pyrometallurgical sludge in the steel manufacturing industry.

Science.gov (United States)

Mocellin, J; Mercier, G; Morel, J L; Blais, J F; Simonnot, M O

2015-08-01

In this laboratory study, a process has been developed for selectively leaching zinc and manganese from pyrometallurgical sludge produced in the steel manufacturing industry. In the first part, the yield of Zn extraction was studied using four factors and four levels of the Box-Behnken response surface design. The optimum conditions for the step of Zn leaching were determined to be a sulfuric acid concentration of 0.25 mol/L, a pulp density of 10%, an extraction temperature of 20 °C, and three stages of leaching. Under such conditions, 75% of the Zn should be leached. For Mn leaching, the optimum conditions were determined to be a sulfuric acid concentration of 0.25 mol/L, a Na2S2O5/Mn stoichiometry of 1, a leaching time of 120 min and two leaching steps. In this case, 100% of the Mn should be leached. Copyright © 2015 Elsevier Ltd. All rights reserved.

Reconfigured state-community relations in Africa’s extractive sectors

DEFF Research Database (Denmark)

Pedersen, Rasmus Hundsbæk; Jacob, Thabit

2017-01-01

The governance of Africa’s extractive sectors has undergone major changes in recent years. Using mainland Tanzania as a case study, this article explores how the relationships between the state, investors and community actors in respect of mining and petroleum investments have developed as a resu...

21 CFR 184.1262 - Corn silk and corn silk extract.

Science.gov (United States)

2010-04-01

... specific limitations: Category of food Maximum level of use in food (as served) 1 Functional use Baked... chapter 10 Do. Soft candy, § 170.3(n)(38) of this chapter 20 Do. All other food categories 4 Do. 1 Parts... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Corn silk and corn silk extract. 184.1262 Section...

25 CFR 170.411 - What may a long-range transportation plan include?

Science.gov (United States)

2010-04-01

...) Social and economic development planning to identify transportation improvements or needs to accommodate... 25 Indians 1 2010-04-01 2010-04-01 false What may a long-range transportation plan include? 170.411 Section 170.411 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN...

25 CFR 170.805 - What are the local, tribal, and BIA roles in transportation facility maintenance?

Science.gov (United States)

2010-04-01

... transportation facility maintenance? 170.805 Section 170.805 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN RESERVATION ROADS PROGRAM BIA Road Maintenance § 170.805 What are the local... Road Maintenance dollars. ...

Phoenix I energy extraction experiment

International Nuclear Information System (INIS)

Hoffman, J.M.; Patterson, E.L.; Tisone, G.C.; Moreno, J.B.

1980-07-01

Energy extraction experiments are reported for the Phoenix I amplifier driven by a discharge-initiated oscillator-preamplifier system operating on mixtures of either SF 6 -HI or SF 6 -C 2 H 6 and an electron-beam-initiated intermediate amplifer (lambda-3) fueled with H 2 and F 2 mixtures. When the oscillator-preamplifier system operated with mixtures of SF 6 -HI the input spectrum to the Phoenix I amplifier contained approx. 28 P-branch vibrational-rotational lines which were almost identical to the input spectrum from the H 2 -F 2 fueled oscillator. In this case the energy extraction measurements were essentially the same as the results obtained with the spectrum produced using H 2 and F 2 mixtures. For an input intensity of 10 7 W/cm 2 , 170 J were extracted from the amplifier. With the SF 6 -C 2 H 6 spectrum, extraction was only obtained from the first three excited vibrational levels. This result indicates that most of the energy in the amplifier could be extracted on the first three excited vibrational levels. It is shown that the extraction results can be fit with a simple two level model. The radius of curvature of the beam was estimated using a lateral shearing interferometer. It was found that the Phoenix I amplifier altered the radius of curvature

Optimization of furfural production from D-xylose with formic acid as catalyst in a reactive extraction system.

Science.gov (United States)

Yang, Wandian; Li, Pingli; Bo, Dechen; Chang, Heying; Wang, Xiaowei; Zhu, Tao

2013-04-01

Furfural is one of the most promising platform chemicals derived from biomass. In this study, response surface methodology (RSM) was utilized to determine four important parameters including reaction temperature (170-210°C), formic acid concentration (5-25 g/L), o-nitrotoluene volume percentage (20-80 vt.%), and residence time (40-200 min). The maximum furfural yield of 74% and selectivity of 86% were achieved at 190°C for 20 g/L formic acid concentration and 75 vt.% o-nitrotoluene by 75 min. The high boiling solvent, o-nitrotoluene, was recommended as extraction solvent in a reactive extraction system to obtain high furfural yield and reduce furfural-solvent separation costs. Although the addition of halides to the xylose solutions enhanced the furfural yield and selectivity, the concentration of halides was not an important factor on the furfural yield and selectivity. Copyright © 2013 Elsevier Ltd. All rights reserved.

Self-government’s factoring

Directory of Open Access Journals (Sweden)

Maciej Tokarski

2011-12-01

Full Text Available Local self-governments are reliable business partners. Such belief, confirmed by long-term experience, results in eager collaboration between financial institutions and these entities. Contrary to its name, local self-governments do not constitute the main beneficiaries of the self-government’s factoring. The enterprises which perform investments commissioned by a local commune, district or province are the principal recipients. Such firms may utilise it independently if they have signed contracts with the proper authority and conduct sale with deferred payment, or they may be forced to utilise factoring when they submit their bids in self-government’s tenders within which a refinance guarantee is required. The main aim of the article is to present the mechanism and features of the self-government’s factoring, as well as the benefits which the entities involved enjoy.

Evaluation of Sun Protection Factor of Zingiber officinale Roscoe Extract by Ultraviolet Spectroscopy Method

OpenAIRE

Manoj A. Suva

2014-01-01

The purpose of present study was to evaluate the sun protection factor (SPF) of aqueous and methanolic extract of rhizomes of Zingiber officinale Roscoe by ultraviolet (UV) spectroscopy method. Aqueous and Methanolic extract of rhizomes of Zingiber officinale having concentration of 200µg/ml and 400µg/ml was prepared respectively and the SPF values were evaluated by UV spectroscopy. In this study, it was found that aqueous extract of Zingiber officinale (200µg/ml) have SPF value about 1.44±0....

25 CFR 170.402 - What is the tribal role in transportation planning?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false What is the tribal role in transportation planning? 170... RESERVATION ROADS PROGRAM Planning, Design, and Construction of Indian Reservation Roads Program Facilities Transportation Planning § 170.402 What is the tribal role in transportation planning? (a) All tribes must prepare...

25 CFR 170.502 - Are management systems required for the IRR Program?

Science.gov (United States)

2010-04-01

... the following systems for the IRR Program: (1) Pavement management; (2) Safety management; (3) Bridge... 25 Indians 1 2010-04-01 2010-04-01 false Are management systems required for the IRR Program? 170... Program Reviews and Management Systems § 170.502 Are management systems required for the IRR Program? (a...

25 CFR 170.900 - What is the purpose of the provisions relating to transportation of hazardous and nuclear waste?

Science.gov (United States)

2010-04-01

... transportation of hazardous and nuclear waste? 170.900 Section 170.900 Indians BUREAU OF INDIAN AFFAIRS... and Nuclear Waste Transportation § 170.900 What is the purpose of the provisions relating to transportation of hazardous and nuclear waste? Sections 170.900 through 170.907 on transportation of nuclear and...

Analysis of factors that influencing the interest of Bali State Polytechnic’s students in entrepreneurship

Science.gov (United States)

Ayuni, N. W. D.; Sari, I. G. A. M. K. K.

2018-01-01

The high rate of unemployment results the economic growth to be hampered. To solve this situation, the government try to change the students’ mindset from becoming a job seeker to become a job creator or entrepreneur. One real action that usually been held in Bali State Polytechnic is Student Entrepreneurial Program. The purpose of this research is to identify and analyze the factors that influence the interest of Bali State Polytechnic’s Students in entrepreneurship, especially in the Entrepreneurial Student Program. Method used in this research is Factor Analysis including Bartlett Test, Kaiser-Mayer Olkin (KMO), Measure of Sampling Adequacy (MSA), factor extraction using Principal Component Analysis (PCA), factor selection using eigen value and scree plot, and factor rotation using orthogonal rotation varimax. Result shows that there are four factors that influencing the interest of Bali State Polytechnic’s Students in Entrepreneurship which are Contextual Factor (including Entrepreneurship Training, Academic Support, Perceived Confidence, and Economic Challenge), Self Efficacy Factor (including Leadership, Mental Maturity, Relation with Entrepreneur, and Authority), Subjective Norm Factor (including Support of Important Relative, Support of Friends, and Family Role), and Attitude Factor (including Self Realization).

Temperature effects on diffusion coefficient for 6-gingerol and 6-shogaol in subcritical water extraction

International Nuclear Information System (INIS)

Anisa, Nor Ilia; Azian, Noor; Sharizan, Mohd; Iwai, Yoshio

2014-01-01

6-gingerol and 6-shogaol are the main constituents as anti-inflammatory or bioactive compounds from zingiber officinale Roscoe. These bioactive compounds have been proven for inflammatory disease, antioxidatives and anticancer. The effect of temperature on diffusion coefficient for 6-gingerol and 6-shogaol were studied in subcritical water extraction. The diffusion coefficient was determined by Fick's second law. By neglecting external mass transfer and solid particle in spherical form, a linear portion of Ln (1-(Ct/Co)) versus time was plotted in determining the diffusion coefficient. 6-gingerol obtained the higher yield at 130°C with diffusion coefficient of 8.582x10 −11 m 2 /s whilst for 6-shogaol, the higher yield and diffusion coefficient at 170°C and 19.417 × 10 −11 m 2 /s.

α-Tubulin Tyrosination and CLIP-170 Phosphorylation Regulate the Initiation of Dynein-Driven Transport in Neurons

Directory of Open Access Journals (Sweden)

Jeffrey J. Nirschl

2016-03-01

Full Text Available Motor-cargo recruitment to microtubules is often the rate-limiting step of intracellular transport, and defects in this recruitment can cause neurodegenerative disease. Here, we use in vitro reconstitution assays with single-molecule resolution, live-cell transport assays in primary neurons, computational image analysis, and computer simulations to investigate the factors regulating retrograde transport initiation in the distal axon. We find that phosphorylation of the cytoskeletal-organelle linker protein CLIP-170 and post-translational modifications of the microtubule track combine to precisely control the initiation of retrograde transport. Computer simulations of organelle dynamics in the distal axon indicate that while CLIP-170 primarily regulates the time to microtubule encounter, the tyrosination state of the microtubule lattice regulates the likelihood of binding. These mechanisms interact to control transport initiation in the axon in a manner sensitive to the specialized cytoskeletal architecture of the neuron.

Radical Scavenging Activity From Ethanolic Extract Of Malvaceae Family’s Flowers

Science.gov (United States)

Artanti, A. N.; Rahmadanny, N.; Prihapsara, F.

2018-04-01

Sea hibiscus flower (Hibiscus tiliaceus L.), shoe flower (Hibiscus rosa-sinensis L.), and turk’s cap flower (Malvaviscus arboreus Cav.) are a plant that belongs to the same family, Malvaceae. There are expected contain of anthocyanins as active compound. Several studied shows that some flowers could protect human body from free radical danger exposure. This study has been done to examine ethanolic extract from malvaceae family’s which has potency as radical scavenger. Antiradical activity assay was determined by DPPH method with IC50 value as parameter. Based on the study the malvaceae family’s flower was contain of tannins, polyphenols, saponin, and anthocyanine. The radical scavenging activity respectively from the lowest to the higest activity are vitamin c (4,05 ppm ± 0,094), Turk’s cap flower (6,80 ppm ± 0,22), shoe flower (14,62 ppm ± 0,104) and sea hibiscus flower (38,8 ppm ± 0,086). The three of the extract was having strong antioxidant activity.

7 CFR 170.4 - Who may participate in the USDA Farmers Market?

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Who may participate in the USDA Farmers Market? 170.4... MARKETING PRACTICES UNDER THE AGRICULTURAL MARKETING ACT OF 1946 USDA FARMERS MARKET § 170.4 Who may participate in the USDA Farmers Market? Members of three groups may participate in the USDA Farmers Markets...

7 CFR 170.1 - To which farmers markets does this rule apply?

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false To which farmers markets does this rule apply? 170.1... MARKETING PRACTICES UNDER THE AGRICULTURAL MARKETING ACT OF 1946 USDA FARMERS MARKET § 170.1 To which farmers markets does this rule apply? This rule applies only to the USDA Farmers Market at headquarters on...

Graphene Oxide Conjugated Magnetic Beads for RNA Extraction.

Science.gov (United States)

Pham, Xuan-Hung; Baek, Ahruem; Kim, Tae Han; Lee, Sang Hun; Rho, Won-Yeop; Chung, Woo-Jae; Kim, Dong-Eun; Jun, Bong-Hyun

2017-08-04

A magnetic material that consists of silica-coated magnetic beads conjugated with graphene oxide (GO) was successfully prepared for facile ribonucleic acid (RNA) extraction. When the GO-modified magnetic beads were applied to separate the RNA from the lysed cell, the cellular RNAs were readily adsorbed to and readily desorbed from the surface of the GO-modified magnetic beads by urea. The amount of RNA extracted by the GO-modified magnetic beads was ≈170 % as much as those of the control extracted by a conventional phenol-based chaotropic solution. These results demonstrate that the facile method of RNA separation by using GO-modified magnetic beads as an adsorbent is an efficient and simple way to purify intact cellular RNAs and/or microRNA from cell lysates. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

25 CFR 170.122 - Can a tribe close a cultural access road?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Can a tribe close a cultural access road? 170.122 Section... ROADS PROGRAM Indian Reservation Roads Program Policy and Eligibility Use of Irr and Cultural Access Roads § 170.122 Can a tribe close a cultural access road? (a) A tribe with jurisdiction over a cultural...

Temperature effects on diffusion coefficient for 6-gingerol and 6-shogaol in subcritical water extraction

Science.gov (United States)

Ilia Anisa, Nor; Azian, Noor; Sharizan, Mohd; Iwai, Yoshio

2014-04-01

6-gingerol and 6-shogaol are the main constituents as anti-inflammatory or bioactive compounds from zingiber officinale Roscoe. These bioactive compounds have been proven for inflammatory disease, antioxidatives and anticancer. The effect of temperature on diffusion coefficient for 6-gingerol and 6-shogaol were studied in subcritical water extraction. The diffusion coefficient was determined by Fick's second law. By neglecting external mass transfer and solid particle in spherical form, a linear portion of Ln (1-(Ct/Co)) versus time was plotted in determining the diffusion coefficient. 6-gingerol obtained the higher yield at 130°C with diffusion coefficient of 8.582x10-11 m2/s whilst for 6-shogaol, the higher yield and diffusion coefficient at 170°C and 19.417 × 10-11 m2/s.

Inhibitors of the epidermal growth factor receptor in apple juice extract.

Science.gov (United States)

Kern, Melanie; Tjaden, Zeina; Ngiewih, Yufanyi; Puppel, Nicole; Will, Frank; Dietrich, Helmut; Pahlke, Gudrun; Marko, Doris

2005-04-01

The polyphenol-rich extract of a consumer-relevant apple juice blend was found to potently inhibit the growth of the human colon cancer cell line HT29 in vitro. The epidermal growth factor receptor (EGFR) and its subsequent signaling cascade play an important role in the regulation of cell proliferation in HT29 cells. The protein tyrosine kinase activity of an EGFR preparation was effectively inhibited by the polyphenol-rich apple juice extract. Treatment of intact cells with this extract resulted in the suppression of the subsequent mitogen-activated protein kinase cascade. Amongst the so far identified apple juice constituents, the proanthocyanidins B1 and B2 as well as quercetin-3-glc (isoquercitrin) and quercetin-3-gal (hyperoside) were found to possess substantial EGFR-inhibitory properties. However, as to be expected from the final concentration of these potential EGFR inhibitors in the original polyphenol-rich extract, a synthetic mixture of the apple juice constituents identified and available so far, including both proanthocyanidins and the quercetin glycosides, showed only marginal inhibitory effects on the EGFR. These results permit the assumption that yet unknown constituents contribute substantially to the potent EGFR-inhibitory properties of polyphenol-rich apple juice extract. In summary, the polyphenol composition of apple juice possesses promising growth-inhibitory properties, affecting proliferation-associated signaling cascades in colon tumor cells.

Image collection: 170 [Togo Picture Gallery[Archive

Lifescience Database Archive (English)

Full Text Available 170 Brachiosaurus_altithorax_NL.png ブラキオサウルス Brachiosaurus Brachiosaurus altithorax ... 生物アイコン,脊索動物門,脊椎動物亜門,爬虫綱,恐竜上目・翼竜上目

Measurements of nuclear polarization and nuclear magnetic moment of 170Tm in 170Tm:SrF2 by optical pumping

International Nuclear Information System (INIS)

Shimomura, K.

1988-01-01

Significant nuclear polarization of unstable 170 Tm in Tm 2+ :SrF 2 was for the first time achieved with β-ray radiation detected optical pumping in solids, providing a new powerful method to measure magnetic moments of unstable nuclei. (author)

Ginsenoside Rg3 enhances radiosensitization of hypoxic oesophageal cancer cell lines through vascular endothelial growth factor and hypoxia inducible factor 1α.

Science.gov (United States)

Ge, Xiaolin; Zhen, Fuxi; Yang, Baixia; Yang, Xi; Cai, Jing; Zhang, Chi; Zhang, Sheng; Cao, Yuandong; Ma, Jianxin; Cheng, Hongyan; Sun, Xinchen

2014-06-01

To determine if the pretreatment of hypoxic human oesophageal carcinoma cell lines (EC109, TE1 and KYSE170) with ginsenoside Rg3 (Rg3) increases their radiosensitivity to X-rays. The growth inhibitory effect of different Rg3 concentrations was measured using the 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide (MTT) assay. Radiation sensitivity was measured using a clone formation assay and flow cytometry was used to measure the effects of Rg3 on radiation-induced apoptosis. Western blot analysis was used to measure the effects of Rg3 on the levels of hypoxia inducible factor (HIF)-1α and vascular endothelial growth factor (VEGF). Rg3 inhibited EC109, TE1 and KYSE170 cell growth in a dose- and time-dependent manner. Pretreatment with 10 µmol/ml Rg3 increased EC109, TE1 and KYSE170 radiosensitivity. Rg3 plus radiation significantly increased the apoptosis rate compared with radiation alone. Rg3 also decreased VEGF and HIF-1α protein levels in EC109 cells in a dose-dependent manner. The combination of Rg3 and radiation increased the fragmentation of double-stranded DNA. Rg3 enhanced the radiosensitivity of human oesophageal carcinoma cell lines cultured under hypoxic conditions possibly by downregulating VEGF and HIF-1α protein levels. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

P1 and N170 components distinguish human-like and animal-like makeup stimuli.

Science.gov (United States)

Luo, Shuwei; Luo, Wenbo; He, Weiqi; Chen, Xu; Luo, Yuejia

2013-06-19

This study used event-related potentials to investigate the sensitivity of P1 and N170 components to human-like and animal-like makeup stimuli, which were derived from pictures of Peking opera characters. As predicted, human-like makeup stimuli elicited larger P1 and N170 amplitudes than did animal-like makeup stimuli. Interestingly, a right hemisphere advantage was observed for human-like but not for animal-like makeup stimuli. Dipole source analyses of 130-200-ms window showed that the bilateral fusiform face area may contribute to the differential sensitivity of the N170 component in response to human-like and animal-like makeup stimuli. The present study suggests that the amplitudes of both the P1 and the N170 are sensitive for the mouth component of face-like stimuli.

78 FR 64525 - U.S. Extractive Industries Transparency Initiative Multi-Stakeholder Group (USEITI MSG) Advisory...

Science.gov (United States)

2013-10-29

... DEPARTMENT OF THE INTERIOR Office of the Secretary [Docket No. ONRR-2012-0003; DS63600000 DR2PS0000.PX8000 134D0102R2] U.S. Extractive Industries Transparency Initiative Multi- Stakeholder Group...: This notice announces the rescheduling of the U.S. Extractive Industries Transparency Initiative...

Physical and social factors determining quality of life for veterans with lower-limb amputation(s)

DEFF Research Database (Denmark)

Christensen, Jan; Ipsen, Thomas; Doherty, Patrick

2016-01-01

of the literature to summarize any evidence on the physical and social determinants for HRQoL in veterans with uni- or bilateral lower-limb amputation(s). Method MEDLINE, EMBASE, PEDro, CINAHL, Scopus and Cochrane databases were searched systematically for eligible studies. Inclusion criteria were: traumatic lower......-limb amputation(s), HRQoL outcome and veterans. Physical and social factors that influence HRQoL were extracted. Results The literature search identified 2073 citations, leading to the inclusion of 10 studies in the systematic review. Physical activity level, sport participation, level of amputation, back pain...

Coacervative extraction of trace lead from natural waters prior to its determination by electrothermal atomic absorption spectrometry

Energy Technology Data Exchange (ETDEWEB)

Hagarová, Ingrid, E-mail: hagarova@fns.uniba.sk; Bujdoš, Marek; Matúš, Peter; Kubová, Jana

2013-10-01

In this work, a relatively simple and sensitive method for separation/preconcentration of trace lead from natural waters prior to its determination by electrothermal atomic absorption spectrometry has been proposed. The method is based on the extraction of Pb–dithizone chelate with coacervates made up of lauric acid in the presence of potassium ions and methanol. Several important factors affecting extraction efficiency such as pH, concentration of lauric acid and dithizone, ionic strength, incubation and centrifugation time were investigated and optimized. After separation of aqueous bulk solution from surfactant-rich phase, the final extract was redissolved by using 500 μl of methanol acidified with 0.2 mol l{sup −1} HNO{sub 3}. Under the optimized conditions (using initial sample volume of 10 ml), enrichment factor of 17.0, detection limit of 0.12 μg l{sup −1}, quantification limit of 0.38 μg l{sup −1}, relative standard deviation of 4.2% (for 2 μg l{sup −1} of Pb; n = 26), linearity of the calibration graph in the range of 0.5–4.0 μg l{sup −1} (with correlation coefficient better than 0.995) were achieved. The method was validated by the analysis of certified reference material (TMDA-61). Extraction recoveries for the CRM, spiked model solutions and spiked natural water samples were in the range of 91–96%. Finally, the method was applied to the separation/preconcentration and determination of trace lead in natural waters. - Highlights: • The potential of coacervates for the extraction of metal ions is examined. • No difficulties in coupling of ETAAS with the proposed CAE are observed. • Achieved preconcentration factor results in enhanced sensitivity. • Analytical performance is confirmed by the reliable determination of trace Pb. • The proposed CAE is ecofriendly and efficient.

Thulium-170 oxide heat source experimental and analytical radiation and shielding study

International Nuclear Information System (INIS)

Tse, A.; Nelson, C.A.

1970-05-01

Radiation dose rates from three thulium-170 oxide sources (20.7, 10.0 and 5.0 thermal watts) were measured through three thicknesses (1/4, 1/2 and 1 inch) of absorber by thermoluminescent dosimetry techniques. Absorber materials used were aluminium, stainless steel, lead, tungsten and depleted uranium. Resultant radiation doses were measured at 19 and 100 cm. Comparison of theoretical dose rates calculated by computer with measured dose rates validated the calculation technique for lead, tungsten and uranium absorbers but not for aluminum and stainless steel. Use of infinite medium build-up factors (B/sub ∞/) was thus validated in computation of dose rates for lead, tungsten and uranium absorbers; use of B/sub ∞/ in computation of dose rates for aluminum and stainless steel absorbers overestimated dose rates vis-a-vis experimentally determined dose rates by an approximate factor of 2

Topical anesthesia: possible risk factor for endophthalmitis after cataract extraction.

Science.gov (United States)

Garcia-Arumi, Jose; Fonollosa, Alex; Sararols, Laura; Fina, Francesc; Martínez-Castillo, Vicente; Boixadera, Ana; Zapata, Miguel A; Campins, Magda

2007-06-01

To assess the relationship between the risk for acute endophthalmitis after cataract extraction and whether certain factors, such as surgeon qualification, numerical order, duration of surgery, operating theater, and type of anesthesia (topical or retrobulbar), could be modified to decrease the risk. Single-center academic practice. Two epidemiological studies were performed: a case-control study and a retrospective cohort study. The surgical records of all patients with clinically diagnosed endophthalmitis within 30 days after cataract surgery performed between February 2002 and September 2003 were reviewed. The endophthalmitis cases were compared with 108 randomly selected controls (4 controls per case). The global incidence of endophthalmitis and the incidence according to type of anesthesia were calculated. Of 5011 cataract extractions performed, 27 cases of endophthalmitis occurred. The incidence was 5.39 per 1000 procedures. An independent statistically significant relationship was found between endophthalmitis and the use of topical anesthesia (odds ratio [OR], 11.8; 95% confidence interval [CI], 2.4-58.7) and surgery longer than 45 minutes (OR, 7.2; 95% CI, 1.7-29.7) but not between the other variables. The incidence of endophthalmitis was 1.8 per 1000 cataract extractions with retrobulbar anesthesia and 6.76 per 1000 with topical anesthesia (relative risk [RR], 3.76; 95% CI, 0.89-15.85). After the start of the study period was extended to May 2001, the incidence of endophthalmitis was 1.3 per 1000 cataract extractions with retrobulbar anesthesia and 8.7 per 1000 with topical anesthesia (RR, 6.72; 95% CI, 1.63-27.63). Results suggest that there may be an association between topical anesthesia and endophthalmitis after cataract extraction.

25 CFR 170.916 - May tribes impose taxes or fees on those performing IRR Program services?

Science.gov (United States)

2010-04-01

... Indian Preference § 170.916 May tribes impose taxes or fees on those performing IRR Program services? Yes... 25 Indians 1 2010-04-01 2010-04-01 false May tribes impose taxes or fees on those performing IRR Program services? 170.916 Section 170.916 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR...

Liberia’s Post-War Development: Key Issues and U.S. Assistance

Science.gov (United States)

2010-05-25

GNI) total: $634.4 million (2008) GNI per capita: $170 (2008) External debt: $1.7 billion (2010 ) Key exports: Rubber, timber, iron, cocoa , gold...for killers whose purpose is to remove various body organs for uses, including consumption , in traditional occult ceremonies that participants...accountability in relation to the extraction of timber, oil and gas, cocoa and other natural resources, including by strengthening implementation and monitoring

48 CFR 1509.170-8 - Contractor Performance Report.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contractor Performance... AGENCY ACQUISITION PLANNING CONTRACTOR QUALIFICATIONS Contractor Performance Evaluations 1509.170-8 Contractor Performance Report. (a) Contractor Performance Reports (interim and final) must be prepared...

Analyse géochimique de la matiére organique extraite des roches sédimentaires. IV. Extraction des roches en faible quantités Geochemical Analysis of Organic Matter Extracted from Sedimentary Rocks Iv. Exraction from Small Amounts of Rock

Directory of Open Access Journals (Sweden)

Monin J. C.

2006-11-01

Full Text Available L'extraction en Soxhlet est inappllcable lorsque les échantillons de roche sont de trop petite taille. A l'occasion de la mise au point du protocole d'extraction correspondant, on examine l'influence d'un certain nombre de conditions opératoires sur le rendement d'extraction : température, durée nature et quantité du solvant, présence de lumière, présence d'air, procédé d'extraction. Pour les hydrocarbures, tant saturés qu'aromatiques, le facteur essentiel est l'agitation du milieu d'extraction ; la nature du solvant n'est pas critique, à condition de ne pas choisir un très mauvais solvant des hydrocarbures : l'extractibilité est en effet plus fonction du pouvoir désorbant vis-à-vis de la roche que du pouvoir solvant proprement dit. Pour les résines et asphalténes, l'interprétation des résultats est délicate, car la frontière n'est pas nette entre produits simplement dissous, produits de solvolyse et, produits de néoformation par interaction solvant-matière organique-matière minérale. II n'existe donc pas de protocole d'extraction recommandable dans l'absolu. Tout dépend des exigences analytiques et aussi pratiques du laboratoire; à l'Institut Français du Pétrole (IFP le protocole retenu est l'extraction en bécher avec agitation magnétique pendant 20 min dans le chroroforme à 50 °C (approximativement; on donne aussi le protocole d'évaporation du solvant et de récupération de l'extrait, qui doit être étudié soigneusement étant donné les faibles quantités mises en jeu. A Soxhlet extractor cannot be used with rock samples that are too small in size. With the development of on extraction procédure for such cases, this article examines the influence of various operating conditions on extraction yield, i. e. temperature, duration, nature and amount of solvent, presence of light, présence of air and extraction process. For both saturated and aromatic hydrocarbons, the essential factor is the stirring of the

Level Densities and Radiative Strength Functions in 170,171Yb

International Nuclear Information System (INIS)

Agvaanluvsan, U.; Schiller, A.; Becker, J.A.; Berstein, L.A.; Guttormsen, M.; Mitchell, G.E.; Rekstad, J.; Siem, S.; Voinov, A.

2003-01-01

Level densities and radiative strength functions in 171 Yb and 170 Yb nuclei have been measured with the 171 Yb( 3 He, 3 He(prime) γ) 171 Yb and 171 Yb( 3 He, αγ) 170 Yb reactions. A simultaneous determination of the nuclear level density and the radiative strength function was made. The present data adds to and is consistent with previous results for several other rare earth nuclei. The method will be briefly reviewed and the result from the analysis will be presented. The radiative strength function for 171 Yb is compared to previously published work.

KINETICS OF ULTRASOUND ASSISTED EXTRACTION OF WEDELOLACTONE FROM Eclipta alba

Directory of Open Access Journals (Sweden)

T. W. Charpe

Full Text Available Abstract Ultrasound assisted extraction of wedelolactone, a major coumestan present in Eclipta alba, is investigated in the present work.Various process parameters such as type of solvent, power, solvent to solid ratio and extraction temperature, which affect the extraction yield, are optimized. In the ultrasound-assisted extraction with final optimized conditions, i.e., methanol as solvent, 170 W power, 60:1 solvent to solid ratio, 50 °C temperature and 60% duty cycle, amaximum extraction yieldof 0.62 mg/g is obtained in 45 minutes. The kinetic model (Peleg's model has been used for the prediction of the yield of wedelolactone in the extract at a given time for all experimental conditions. The values of predicted yields show good agreement with the experimental data for all parameters, i.e., power, solvent to solid ratio and temperature. The extraction of wedelolactone from Eclipta alba is also carried out by conventional extraction methods, i.e., Soxhlet and batch extraction. Ultrasound-assisted extraction gives higher extraction yield in less time as compared to batch extraction (0.41 mg/g in 90 min and Soxhlet extraction(0.7 mg/g in 360 min. The ultrasound-assisted extraction of wedelolactone from Eclipta alba is an effective way of extraction with the advantages of lower time and higher extraction.

Applications of the Automated SMAC Modal Parameter Extraction Package

International Nuclear Information System (INIS)

MAYES, RANDALL L.; DORRELL, LARRY R.; KLENKE, SCOTT E.

1999-01-01

An algorithm known as SMAC (Synthesize Modes And Correlate), based on principles of modal filtering, has been in development for a few years. The new capabilities of the automated version are demonstrated on test data from a complex shell/payload system. Examples of extractions from impact and shaker data are shown. The automated algorithm extracts 30 to 50 modes in the bandwidth from each column of the frequency response function matrix. Examples of the synthesized Mode Indicator Functions (MIFs) compared with the actual MIFs show the accuracy of the technique. A data set for one input and 170 accelerometer outputs can typically be reduced in an hour. Application to a test with some complex modes is also demonstrated

25 CFR 170.807 - What must BIA include when it develops an IRR Transportation Facilities Maintenance Management...

Science.gov (United States)

2010-04-01

... Transportation Facilities Maintenance Management System? 170.807 Section 170.807 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN RESERVATION ROADS PROGRAM BIA Road Maintenance § 170.807 What must BIA include when it develops an IRR Transportation Facilities Maintenance Management System...

Test del PWC 170 adaptado para determinar la capacidad de trabajo especial en beisbolistas escolares / Adapted PWC 170 test to determine special work abilities in school baseball players

Directory of Open Access Journals (Sweden)

Sadiel López-Leal

2016-07-01

Full Text Available Resumen Se adaptó el test de PWC 170, según el método de Karpman modificado para el bateo, con el propósito de determinar la capacidad de trabajo especial durante este ejercicio en beisbolistas de la categoría 9-10 años del área deportiva Julio Antonio Mella, ciudad de Camagüey, Cuba. Se estudiaron 15 atletas. Como métodos se emplearon la revisión bibliográfica sobre el proceso de control de preparación del deportista y el control médico deportivo, además se realizó la entrevista a entrenadores y la observación de clases. De su aplicación se obtuvo como resultado una alta correlación entre ambas experiencias y buena estabilidad, además de positivas valoraciones de todos los indicadores por parte de los entrenadores; de ahí que consideren efectiva esta prueba para evaluar objetivamente la capacidad de trabajo especial en beisbolistas escolares de Camagüey. Abstract The PWC 170 test was adapted, according to Karpman’s model modified for batting, with the purpose of determining special work abilities during the game in 9-10 years old baseball players of Julio Antonio Mella sports area, Camagüey city, Cuba. The sample was of 15 athletes. Some of the scientific methods used were bibliographic revision on the control process of the athletes training, coach interviews and class observation. As a result the author detected a high correlation of experiences, good stability and positive coach assessment on every indicator. Therefore, this test was considered effective to objectively evaluate special work abilities in school baseball players from Camagüey.

Psychological factors and coronary heart disease

Directory of Open Access Journals (Sweden)

Hadži-Pešić Marina

2007-01-01

Full Text Available Coronary heart disease (CAD results from an interaction of different somatic, environmental and behavioral risk factors. Commonly, development of CAD is associated with arterial hypertension, dyslipidemia, diabetes mellitus, smoking, sedentary life style and the like. Psychological factors in their own sake or in combination with other risk factors are also important for genesis of CAD. In this study, 170 people that were diagnosed with CAD and 170 healthy controls of corresponding sex and age were compared for anxiety, aggressiveness and Eysenck's two personality dimension. The data indicate that patients with CAD have very low level of anxiety and aggressiveness and very high level of neuroticism relative to the controls. .

The naked truth: the face and body sensitive N170 response is enhanced for nude bodies.

Directory of Open Access Journals (Sweden)

Jari K Hietanen

Full Text Available Recent event-related potential studies have shown that the occipitotemporal N170 component--best known for its sensitivity to faces--is also sensitive to perception of human bodies. Considering that in the timescale of evolution clothing is a relatively new invention that hides the bodily features relevant for sexual selection and arousal, we investigated whether the early N170 brain response would be enhanced to nude over clothed bodies. In two experiments, we measured N170 responses to nude bodies, bodies wearing swimsuits, clothed bodies, faces, and control stimuli (cars. We found that the N170 amplitude was larger to opposite and same-sex nude vs. clothed bodies. Moreover, the N170 amplitude increased linearly as the amount of clothing decreased from full clothing via swimsuits to nude bodies. Strikingly, the N170 response to nude bodies was even greater than that to faces, and the N170 amplitude to bodies was independent of whether the face of the bodies was visible or not. All human stimuli evoked greater N170 responses than did the control stimulus. Autonomic measurements and self-evaluations showed that nude bodies were affectively more arousing compared to the other stimulus categories. We conclude that the early visual processing of human bodies is sensitive to the visibility of the sex-related features of human bodies and that the visual processing of other people's nude bodies is enhanced in the brain. This enhancement is likely to reflect affective arousal elicited by nude bodies. Such facilitated visual processing of other people's nude bodies is possibly beneficial in identifying potential mating partners and competitors, and for triggering sexual behavior.

Experience in programming Assembly language of CDC CYBER 170/750 computer

International Nuclear Information System (INIS)

Caldeira, A.D.

1987-10-01

Aiming to optimize processing time of BCG computer code in the CDC CYBER 170/750 computer, the FORTRAN-V language of INTERP subroutine was converted to Assembly language. The BCG code was developed for solving neutron transport equation by iterative method, and the INTERP subroutine is innermost loop of the code carrying out 5 interpolation types. The central processor unit Assembly language of the CDC CYBER 170/750 computer and its application in implementing the interpolation subroutine of BCG code are described. (M.C.K.)

Fast, visual specialization for reading in English revealed by the topography of the N170 ERP response

Directory of Open Access Journals (Sweden)

McCandliss Bruce D

2005-08-01

Full Text Available Abstract Background N170 effects associated with visual words may be related to perceptual expertise effects that have been demonstrated for faces and other extensively studied classes of visual stimuli. Although face and other object expertise effects are typically bilateral or right-lateralized, the spatial topography of reading-related N170 effects are often left-lateralized, providing potential insights into the unique aspects of reading-related perceptual expertise. Methods Extending previous research in German 1, we use a high-density channel array to characterize the N170 topography for reading-related perceptual expertise in English, a language with inconsistent spelling-to-sound mapping. N170 effects related to overall reading-related expertise are defined by contrasting responses to visual words versus novel symbol strings. By contrasting each of these conditions to pseudowords, we examined how this reading-related N170 effect generalizes to well-ordered novel letter strings. Results A sample-by-sample permutation test computed on word versus symbol ERP topographies revealed differences during two time windows corresponding to the N170 and P300 components. Topographic centroid analysis of the word and symbol N170 demonstrated significant differences in both left-right as well as inferior-superior dimensions. Words elicited larger N170 negativities than symbols at inferior occipito-temporal channels, with the maximal effect over left inferior regions often unsampled in conventional electrode montages. Further contrasts produced inferior-superior topographic effects for the pseudoword-symbol comparison and left-lateralized topographic effects for the word-pseudoword comparison. Conclusion Fast specialized perception related to reading experience produces an N170 modulation detectable across different EEG systems and different languages. Characterization of such effects may be improved by sampling with greater spatial frequency recordings

A 2 MW, CW, 170 GHz gyrotron for ITER

International Nuclear Information System (INIS)

Piosczyk, B.; Arnold, A.; Alberti, S.

2003-01-01

A 140 GHz gyrotron for CW operation is under development for the stellarator W7-X. With a prototype tube a microwave output power of about 0.9 MW has been obtained in pulses up to 180 s, limited by the capability of the high voltage power supply. The development work on coaxial cavity gyrotrons has demonstrated the feasibility of manufacturing of a 2 MW, CW 170 GHz tube that could be used for ITER. The problems specific to the coaxial arrangement have been investigated and all relevant information needed for an industrial realization of a coaxial gyrotron have been obtained in short pulse experiments (up to 17 ms). The suitability of critical components for a 2 MW, CW coaxial gyrotron has been studied and a first integrated design has been done. (author)

7 CFR 170.2 - Is the USDA Farmers Market a producer-only market?

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Is the USDA Farmers Market a producer-only market? 170...) MISCELLANEOUS MARKETING PRACTICES UNDER THE AGRICULTURAL MARKETING ACT OF 1946 USDA FARMERS MARKET § 170.2 Is the USDA Farmers Market a producer-only market? Yes. A producer-only market is one that does not offer...

Cognitive Bias by Gender Interaction on N170 Response to Emotional Facial Expressions in Major and Minor Depression.

Science.gov (United States)

Wu, Xingqu; Chen, Jiu; Jia, Ting; Ma, Wentao; Zhang, Yan; Deng, Zihe; Yang, Laiqi

2016-03-01

States of depression are considered to relate to a cognitive bias reactivity to emotional events. Moreover, gender effect may influence differences in emotional processing. The current study is to investigate whether there is an interaction of cognitive bias by gender on emotional processing in minor depression (MiD) and major depression (MaD). N170 component was obtained during a visual emotional oddball paradigm to manipulate the processing of emotional information in 33 MiD, 36 MaD, and 32 controls (CN). Compared with CN, in male, both MiD and MaD had lower N170 amplitudes for happy faces, but MaD had higher N170 amplitudes for sad faces; in female, both MiD and MaD had lower N170 amplitudes for happy and neutral faces, but higher N170 amplitudes for sad faces. Compared with MaD in male, MiD had higher N170 amplitudes for happy faces, lower N170 amplitudes for sad faces; in female, MiD only had higher N170 amplitudes for sad faces. Interestingly, a negative relationship was observed between N170 amplitude and the HDRS score for identification of happy faces in depressed patients while N170 amplitude was positively correlated with the HDRS score for sad faces identification. These results provide novel evidence for the mood-brightening effect with an interaction of cognitive bias by gender on emotional processing. It further suggests that female depression may be more vulnerable than male during emotional face processing with the unconscious negative cognitive bias and depressive syndromes may exist on a spectrum of severity on emotional face processing.

Brain response during the M170 time interval is sensitive to socially relevant information.

Science.gov (United States)

Arviv, Oshrit; Goldstein, Abraham; Weeting, Janine C; Becker, Eni S; Lange, Wolf-Gero; Gilboa-Schechtman, Eva

2015-11-01

Deciphering the social meaning of facial displays is a highly complex neurological process. The M170, an event related field component of MEG recording, like its EEG counterpart N170, was repeatedly shown to be associated with structural encoding of faces. However, the scope of information encoded during the M170 time window is still being debated. We investigated the neuronal origin of facial processing of integrated social rank cues (SRCs) and emotional facial expressions (EFEs) during the M170 time interval. Participants viewed integrated facial displays of emotion (happy, angry, neutral) and SRCs (indicated by upward, downward, or straight head tilts). We found that the activity during the M170 time window is sensitive to both EFEs and SRCs. Specifically, highly prominent activation was observed in response to SRC connoting dominance as compared to submissive or egalitarian head cues. Interestingly, the processing of EFEs and SRCs appeared to rely on different circuitry. Our findings suggest that vertical head tilts are processed not only for their sheer structural variance, but as social information. Exploring the temporal unfolding and brain localization of non-verbal cues processing may assist in understanding the functioning of the social rank biobehavioral system. Copyright © 2015 Elsevier Ltd. All rights reserved.

Factors Controlling Redox Speciation of Plutonium and Neptunium in Extraction Separation Processes

Energy Technology Data Exchange (ETDEWEB)

Paulenova, Alena [Principal Investigator; Vandegrift, III, George F. [Collaborator

2013-09-24

The objective of the project was to examine the factors controlling redox speciation of plutonium and neptunium in UREX+ extraction in terms of redox potentials, redox mechanism, kinetics and thermodynamics. Researchers employed redox-speciation extractions schemes in parallel to the spectroscopic experiments. The resulting distribution of redox species w studied uring spectroscopic, electrochemical, and spectro-electrochemical methods. This work reulted in collection of data on redox stability and distribution of redox couples in the nitric acid/nitrate electrolyte and the development of redox buffers to stabilize the desired oxidation state of separated radionuclides. The effects of temperature and concentrations on the redox behavior of neptunium were evaluated.

The construction of factorized S-matrices

International Nuclear Information System (INIS)

Chudnovsky, D.V.

1981-01-01

We study the relationships between factorized S-matrices given as representations of the Zamolodchikov algebra and exactly solvable models constructed using the Baxter method. Several new examples of symmetric and non-symmetric factorized S-matrices are proposed. (orig.)

41 CFR 102-73.170 - What types of special purpose space may the Department of Agriculture lease?

Science.gov (United States)

2010-07-01

... purpose space may the Department of Agriculture lease? 102-73.170 Section 102-73.170 Public Contracts and... § 102-73.170 What types of special purpose space may the Department of Agriculture lease? The Department of Agriculture is delegated the authority to lease the following types of special purpose space: (a...

40 Gbit/s NRZ Packet-Length Insensitive Header Extraction for Optical Label Switching Networks

DEFF Research Database (Denmark)

Seoane, Jorge; Kehayas, E; Avramopoulos, H.

2006-01-01

A simple method for 40 Gbit/s NRZ header extraction based on envelope detection for optical label switching networks is presented. The scheme is insensitive to packet length and spacing and can be single-chip integrated cost-effectively......A simple method for 40 Gbit/s NRZ header extraction based on envelope detection for optical label switching networks is presented. The scheme is insensitive to packet length and spacing and can be single-chip integrated cost-effectively...

Comparison of sEMG-Based Feature Extraction and Motion Classification Methods for Upper-Limb Movement

Directory of Open Access Journals (Sweden)

Shuxiang Guo

2015-04-01

Full Text Available The surface electromyography (sEMG technique is proposed for muscle activation detection and intuitive control of prostheses or robot arms. Motion recognition is widely used to map sEMG signals to the target motions. One of the main factors preventing the implementation of this kind of method for real-time applications is the unsatisfactory motion recognition rate and time consumption. The purpose of this paper is to compare eight combinations of four feature extraction methods (Root Mean Square (RMS, Detrended Fluctuation Analysis (DFA, Weight Peaks (WP, and Muscular Model (MM and two classifiers (Neural Networks (NN and Support Vector Machine (SVM, for the task of mapping sEMG signals to eight upper-limb motions, to find out the relation between these methods and propose a proper combination to solve this issue. Seven subjects participated in the experiment and six muscles of the upper-limb were selected to record sEMG signals. The experimental results showed that NN classifier obtained the highest recognition accuracy rate (88.7% during the training process while SVM performed better in real-time experiments (85.9%. For time consumption, SVM took less time than NN during the training process but needed more time for real-time computation. Among the four feature extraction methods, WP had the highest recognition rate for the training process (97.7% while MM performed the best during real-time tests (94.3%. The combination of MM and NN is recommended for strict real-time applications while a combination of MM and SVM will be more suitable when time consumption is not a key requirement.

Monitoring of treatment with vitamin K antagonists: recombinant thromboplastins are more sensitive to factor VII than tissue-extract thromboplastins.

Science.gov (United States)

Biedermann, J S; van den Besselaar, A M H P; de Maat, M P M; Leebeek, F W G; Kruip, M J H A

2017-03-01

Essentials Differences in sensitivity to factor VII (FVII) have been suggested between thromboplastins. FVII-induced International Normalized Ratio (INR) changes differ between commercial reagents. Recombinant human thromboplastins are more sensitive to FVII than tissue-extract thromboplastins. Thromboplastin choice may affect FVII-mediated INR stability. Background Differences regarding sensitivity to factor VII have been suggested for recombinant human and tissue-extract thromboplastins used for International Normalized Ratio (INR) measurement, but the evidence is scarce. Differences in FVII sensitivity are clinically relevant, as they can affect INR stability during treatment with vitamin K antagonists (VKAs). Objectives To determine whether commercial thromboplastins react differently to changes in FVII. Methods We studied the effect of addition of FVII on the INR in plasma by using three tissue-extract (Neoplastin C1+, Hepato Quick, and Thromborel S) and three recombinant human (Recombiplastin 2G, Innovin, and CoaguChek XS) thromboplastins. Three different concentrations of purified human FVII (0.006, 0.012 and 0.062 μg mL -1 plasma), or buffer, were added to five certified pooled plasmas of patients using VKAs (INR of 1.5-3.5). Changes in FVII activity were measured with two bioassays (Neoplastin and Recombiplastin), and relative INR changes were compared between reagents. Results After addition of 0.062 μg mL -1 FVII, FVII activity in the pooled plasmas increased by approximately 20% (Neoplastin) or 32% (Recombiplastin) relative to the activity in pooled normal plasma. All thromboplastins showed dose-dependent INR decreases. The relative INR change in the pooled plasmas significantly differed between the six thromboplastins. No differences were observed among recombinant or tissue-extract thromboplastins. Pooled results indicated that the FVII-induced INR change was greater for recombinant than for tissue-extract thromboplastins. Conclusions Differences

48 CFR 1602.170-9 - Health benefits plan.

Science.gov (United States)

2010-10-01

... EMPLOYEES HEALTH BENEFITS ACQUISITION REGULATION GENERAL DEFINITIONS OF WORDS AND TERMS Definitions of FEHBP Terms 1602.170-9 Health benefits plan. Health benefits plan means a group insurance policy, contract... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Health benefits plan. 1602...

ALnS.sub.2./sub.:RE (A=K, Rb; Ln=La, Gd, Lu, Y): new optical materials family

Czech Academy of Sciences Publication Activity Database

Jarý, Vítězslav; Havlák, Lubomír; Bárta, J.; Mihóková, Eva; Buryi, Maksym; Nikl, Martin

2016-01-01

Roč. 170, č. 2 (2016), s. 718-735 ISSN 0022-2313 R&D Projects: GA ČR GA13-09876S; GA TA ČR TA01011017 Institutional support: RVO:68378271 Keywords : ternary sulfide * luminescence * x-ray diffraction * EPR * rare-earth doping * white LED Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 2.686, year: 2016

Phytochemical Screening, Alpha-Glucosidase Inhibition, Antibacterial and Antioxidant Potential of Ajuga bracteosa Extracts.

Science.gov (United States)

Hafeez, Kokab; Andleeb, Saiqa; Ghousa, Tahseen; Mustafa, Rozina G; Naseer, Anum; Shafique, Irsa; Akhter, Kalsoom

2017-01-01

Ajuga bracteosa, a medicinal herb, is used by local community to cure a number of diseases such as inflammation, jaundice bronchial asthma, cancer and diabetes. The aim of present work was to evaluate the antioxidant potential, in vitro antidiabetic and antimicrobial effects of A. bracteosa. n-hexane, ethyl acetate, chloroform, acetone, methanol and aqueous extracts of Ajuga bracteosa roots, were prepared via maceration. Antibacterial activity was carried out by agar well diffusion method. Quantitative and qualitative phytochemical screening was done. The antioxidant activity was determined by iron (II) chelating activity, iron reducing power, DPPH, and ABTS free radical scavenging methods, Antidiabetic activity was evaluated through inhibition of α-glucosidase assay. Phytochemical analysis showed the presence of phenols, flavonoids, tannins, saponins, quinines, terpenoids, xanthoproteins, glycosides, carbohydrates, steroids, phytosterols and amino acids. DPPH and ABTS potential values were recorded as 61.92% to 88.84% and 0.11% to 38.82%, respectively. Total phenolic and total flavonoid contents were expressed as gallic acid and rutin equivalents. Total iron content was expressed as FeSO4 equivalents. Chloroform and n-hexane extracts showed significant enzyme inhibition potential with IC50 values of 29.92 μg/ml and 131.7 μg/ml respectively. Aqueous extract showed maximum inhibition of E. coli, S. typhimurium, E. amnigenus, S. pyogenes, and S. aureus, (18.0±1.0 mm, 12.5±0.7 mm, 17.0±0.0 mm, 11.0±0.0 mm and 15.3±2.0 mm mm), respectively. Similarly, n-hexane extract showed maximum inhibition of E. coli, E. amnigenus, S. aureus (11.6±1.5 mm; 11.3±1.5 mm; 13.3±0.5 mm). This study also shows that n-hexane, chloroform, ethyl acetate and aqueous extracts of A. bracteosa root possess α-glucosidase inhibitory activities and therefore it may be used as hypoglycemic agents in the management of postprandial hyperglycemia. Ajuga bracteosa root extracts may provide a

Nature differences of humic acids fractions induced by extracted sequence as explanatory factors for binding characteristics of heavy metals.

Science.gov (United States)

Shi, Wenjing; Lü, Changwei; He, Jiang; En, He; Gao, Manshu; Zhao, Boyi; Zhou, Bin; Zhou, Haijun; Liu, Hualin; Zhang, Yu

2018-06-15

The composition and structure of Humic acid (HA) is so heterogeneous that it brings significant barriers to investigate the interaction between HA and heavy metal ions. The isolation of HA with relatively homogeneity is a key to reveal the binding mechanisms between HA and heavy metals. In this work, ten HA fractions (HAs) were obtained by sequential alkali extraction procedure and nature differences of the extracted HAs were considered as explanatory factors for binding characteristics of Cu 2+ , Pb 2+ and Cd 2+ . The results indicate that more large molecular weight (MW) HA subunits, less carboxyl and phenolic group contents, weaker aromaticity and polarity were measured with increasing extractions, inducing weaker binding capacity of HAs. Ligand binding and bi-Langmuir models indicated that the sorption capacity and binding affinity of earlier extracted HAs were higher than the latter ones. The peak area changes at 3427, 1599, and 619 cm -1 pre- and post-adsorption in FTIR spectra suggested carboxyl, phenolic and nitrogen-containing groups were involved in the adsorption process. At the same time, the peak area difference between HAs and HAs-metal (ΔS) of phenolic groups were 8.22-20.50, 6.81-21.11 and 10.66-19.80% for Cu 2+ , Pb 2+ and Cd 2+ , respectively, ΔS of carboxyl groups 6.64-17.03, 8.96-16.82 and 9.45-17.85% for Cu 2+ , Pb 2+ and Cd 2+ , respectively, ΔS of nitrogen-containing groups 0.33-0.48, 0.20-1.38 and 0.31-0.59% for Cu 2+ , Pb 2+ and Cd 2+ , respectively. ΔS of phenolic and carboxyl groups were larger than those of nitrogen-containing groups, implying that these two groups were the predominant binding sites suppliers for metal ions, which were also supported by the results of correlation analysis. This work is helpful to insight the environmental impacts of natural organic matter and the fate of heavy metals in natural environment. Copyright © 2018 Elsevier Inc. All rights reserved.

Functional analysis of U1-70K interacting SR proteins in pre-mRNA splicing in Arabidopsis

International Nuclear Information System (INIS)

Reddy, A.S.N.

2008-01-01

SR45 mobility by ATP and a transcriptional inhibitor is in contrast to the mobility of SR family splicing factors in animals and suggests fundamental differences in the movement of plant and animals splicing factors. In vivo interaction of U170K with SR45: To analyze the interaction of U170K with SR45, we expressed these proteins fused to RFP and GFP respectively, in protoplasts. Both the reporters co-localized to the same subnuclear domains. To determine direct interaction of these proteins, we fused full-length U170K to one part of split YFP and full-length or truncated version of SR45 to the second half of split YFP. Coexpession of these split YFP constructs resulted in reconstitution of YFP in speckles, suggesting direction interaction of these proteins in vivo (Ali et al., 2008). SR45 is a Novel Plant-Specific Splicing Factor and is Involved in Regulating Multiple Developmental Processes: Using an in vitro splicing complementation assay, we showed that SR45 is an essential splicing factor. The sr45-1 mutant exhibited a number of developmental abnormalities. Further analysis of flowering time has shown that the autonomous pathway of flowering is affected in the mutant. Expression analysis of several flowering genes has revealed that FLC, a key flowering repressor, is up-regulated in the SR45 mutant. Further, alternative splicing pattern of several other SR genes was altered in the sr45-1 mutant in a tissue-specific manner. Hence, the observed pleiotropic effects on various aspects of development are likely due to altered level of SR protein isoforms, which in turn regulate the splicing of other pre-mRNAs. Expression of wild-type SR45 in the mutant complemented the phenotypic defects and changes in alternative splicing of SR genes. SR45 thus is a novel plant-specific splicing factor and plays a crucial role in multiple developmental processes.

Clinical - cardiologic data of 170 dogs - general aspects of diagnosis and therapy

International Nuclear Information System (INIS)

Bohn, F.K.

1994-01-01

The paper presents an actual continuous cardiologic follow up study on 170 unselected dogs. Each proband underwent a complete cardiologic examination (history, auscultation, ECG, radiologic examination, in some cases also echocardiography). Data were grouped by age, sex, breed, congenital and acquired cardiac diseases, and by therapy. 81 (47.65 percent) of the 170 dogs were suffering from an acquired, 25 (14.70 percent) from a congenital cardiac disease. 64 dogs (37.65 percent) showedno clinical signs of heart disease

Modification of radiation therapy by RP-170, hypoxic cell sensitizer and OK-432, biological response modifier (BRM)

International Nuclear Information System (INIS)

Murayama, Chieko; Mori, Tomoyuki; Tamauchi, Hidekazu

1995-01-01

Studies have shown that the combination therapy with RP-170, irradiation and OK-432 could produce significantly higher antitumor effect. The multiple local administration of OK-432 showed superior sensitizing effect in tumor growth delay, tumor control and survival rate. DMF from TCD 50 assay was 2.09 which might be equivalent to that from irradiation with over several hundred mg/kg of RP-170. Additionally combined with 50 mg/kg RP-170, nearly available dose in clinical use, the combined treatment with RP-170, irradiation and OK-432 produced DMF of 1.4, which could be gotten by over 100 mg/kg of RP-170. The success of this combination therapy on murine tumors might also suggest a possibility for a great benefit in clinical radiotherapy. More detailed investigations, histological and immunological research, are under progress. 14 refs., 2 tabs., 3 figs

The Scalp Time-Varying Networks of N170: Reference, Latency, and Information Flow

Directory of Open Access Journals (Sweden)

Yin Tian

2018-04-01

Full Text Available Using the scalp time-varying network method, the present study is the first to investigate the temporal influence of the reference on N170, a negative event-related potential component (ERP appeared about 170 ms that is elicited by facial recognition, in the network levels. Two kinds of scalp electroencephalogram (EEG references, namely, AR (average of all recording channels and reference electrode standardization technique (REST, were comparatively investigated via the time-varying processing of N170. Results showed that the latency and amplitude of N170 were significantly different between REST and AR, with the former being earlier and smaller. In particular, the information flow from right temporal-parietal P8 to left P7 in the time-varying network was earlier in REST than that in AR, and this phenomenon was reproduced by simulation, in which the performance of REST was closer to the true case at source level. These findings indicate that reference plays a crucial role in ERP data interpretation, and importantly, the newly developed approximate zero-reference REST would be a superior choice for precise evaluation of the scalp spatio-temporal changes relating to various cognitive events.

25 CFR 170.501 - What happens when the review process identifies areas for improvement?

Science.gov (United States)

2010-04-01

... identifies areas for improvement? When the review process identifies areas for improvement: (a) The regional... 25 Indians 1 2010-04-01 2010-04-01 false What happens when the review process identifies areas for improvement? 170.501 Section 170.501 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND...

Extraction systems for the study of dubnium

International Nuclear Information System (INIS)

Gates, J.M.; Sudowe, R.; Ali, M.N.; Calvert, M.G.; Dragojevic, I.; Ellison, P.A.; Garcia, M.A.; Gharibyan, N.; Gregorich, K.E.; Nelson, S.L.; Neumann, S.H.; Parsons-Moss, T.; Stavsetra, L.; Nitsche, H.

2007-01-01

The chemistry of transactinide elements (Z (ge) 104) is a topic of great interest in current nuclear chemistry research. The chemical systems that can be used in these studies are limited by the short half-lives of the isotopes and the small production rates of atoms per minute or even atoms per week. In the initial investigations, the chemistry used had to be very selective to the periodic group of interest to separate the transactinide atom from all the other unwanted nuclear reaction products, e.g., transfer products. By using the Berkeley Gas-filled Separator (BGS) as a physical pre-separator, we are able concentrate on systems that are selective between the members of the group of interest, because all other interfering products and the beam are being suppressed by the BGS [1]. We are developing suitable extraction systems for the study of element 105, dubnium. For this purpose we have studied the extraction of niobium and tantalum, the lighter homologs of dubnium, from mineral acids with different organophosphorus compounds. All studies were performed online, using short-lived niobium and tantalum produced in the 124 Sn( 51 V,5n) 170 Ta and 74 Se( 18 O,p3n) 88 Nb reactions. This allowed for the study of the lighter homologues at metal concentrations of 10 -16 M. At these low metal concentrations, the formation of polymeric species is largely prohibited. As seen in Fig. 1, by varying the extractant and the hydrochloric acid concentration from 1 to 11 M, we are able to see a difference in extraction behavior between niobium and tantalum. While the system is suitable for determining chemical differences between the lighter homologues, the extraction of tantalum from hydrochloric acid shows slow kinetics. Figure 2 shows that after 90 seconds of mixing, the system is not in equilibrium. However, experiments indicate that equilibrium is reached faster at higher acid concentrations. We have studied the influence of hydrogen ion concentration on the extraction

48 CFR 411.170 - Brand name or equal.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Brand name or equal. 411... ACQUISITION PLANNING DESCRIBING AGENCY NEEDS Selecting and Developing Requirements Documents 411.170 Brand name or equal. (a) A “brand name or equal” purchase description shall include the following type of...

Induction of MAP Kinase Homologues during Growth and Morphogenetic Development of Karnal Bunt (Tilletia indica) under the Influence of Host Factor(s) from Wheat Spikes

Science.gov (United States)

Gupta, Atul K.; Seneviratne, J. M.; Joshi, G. K.; Kumar, Anil

2012-01-01

Signaling pathways that activate different mitogen-activated protein kinases (MAPKs) in response to certain environmental conditions, play important role in mating type switching (Fus3) and pathogenicity (Pmk1) in many fungi. In order to determine the roles of such regulatory genes in Tilletia indica, the causal pathogen of Karnal bunt (KB) of wheat, semi-quantitative and quantitative RT-PCR was carried out to isolate and determine the expression of MAP kinase homologues during fungal growth and development under in vitro culture. Maximum expression of TiFus3 and TiPmk1 genes were observed at 14th and 21st days of culture and decreased thereafter. To investigate whether the fungus alters the expression levels of same kinases upon interaction with plants, cultures were treated with 1% of host factors (extracted from S-2 stage of wheat spikes). Such treatment induced the expression of MAPks in time dependent manner compared to the absence of host factors. These results suggest that host factor(s) provide certain signal(s) which activate TiFus3 and TiPmk1 during morphogenetic development of T. indica. The results also provides a clue about the role of host factors in enhancing the disease potential due to induction of MAP kinases involved in fungal development and pathogenecity. PMID:22547988

25 CFR 170.404 - What happens when a tribe uses its IRR Program construction funds for transportation planning?

Science.gov (United States)

2010-04-01

... of Indian Reservation Roads Program Facilities Transportation Planning § 170.404 What happens when a... 25 Indians 1 2010-04-01 2010-04-01 false What happens when a tribe uses its IRR Program construction funds for transportation planning? 170.404 Section 170.404 Indians BUREAU OF INDIAN AFFAIRS...

41 CFR 102-75.170 - What happens to the related personal property in a structure scheduled for demolition?

Science.gov (United States)

2010-07-01

... consideration should be given to designating items having possible historical or artistic value as personal... related personal property in a structure scheduled for demolition? 102-75.170 Section 102-75.170 Public... As Personal Property § 102-75.170 What happens to the related personal property in a structure...

Extracting $\\gamma$ from $B_{s(d)} \\to J/\\psi K_{S}$ and $B_{d(s)} \\to D^{+}_{d(s)} D^{-}_{d(s)}$

CERN Document Server

Fleischer, Robert

1999-01-01

A completely general parametrization of the time-dependent decay rates of the modes $B_s\\to J/\\psi K_S$ and $B_d\\to J/\\psi K_S$ is given, which are related to each other through the $U$-spin flavour symmetry of strong interactions. Owing to the interference of current--current and penguin processes, the $B_s\\to J/\\psi K_S$ observables probe the angle $\\gamma$ of the unitarity triangle. Using the $U$-spin symmetry, the overall normalization of the $B_s\\to J/\\psi K_S$ rate can be fixed with the help of the CP-averaged $B_d\\to J/\\psi K_{\\rm S}$ rate, providing a new strategy to determine $\\gamma$. This extraction of $\\gamma$ is not affected by any final-state-interaction effects, and its theoretical accuracy is only limited by $U$-spin-breaking corrections. As a by-product, this strategy allows us to take into account also the penguin effects in the determination of $\\beta$ from $B_d\\to J/\\psi K_S$, which are presumably very small, and to predict the direct CP asymmetry arising in this mode. An analogous strateg...

Effect of rosella ( Hibiscus sabdariffa L ) extract on glutathione-S ...

African Journals Online (AJOL)

Purpose: To determine the effect of rosella (Hibiscus sabdariffa L) extract on glutathione-S-trasferase (GST) activity and its hepatoprotective effect. Methods: A total of 25 rats were divided randomly into 5 groups (5 rats per group). Group I served as the baseline, group II was the negative control group, while groups III, IV and ...

Soil DNA extraction procedure influences protist 18S rRNA gene community profiling outcome

DEFF Research Database (Denmark)

Santos, Susana S.; Nunes, Ines Marques; Nielsen, Tue K.

2017-01-01

Advances in sequencing technologies allow deeper studies of the soil protist diversity and function. However, little attention has been given to the impact of the chosen soil DNA extraction procedure to the overall results. We examined the effect of three acknowledged DNA recovery methods, two...... manual methods (ISOm-11063, GnS-GII) and one commercial kit (MoBio), on soil protist community structures obtained from different sites with different land uses. Results from 18S rRNA gene amplicon sequencing suggest that DNA extraction method significantly affect the replicate homogeneity, the total...... number of operational taxonomic units (OTUs) recovered and the overall taxonomic structure and diversity of soil protist communities. However, DNA extraction effects did not overwhelm the natural variation among samples, as the community data still strongly grouped by geographical location...

Korean Red Ginseng Extract Attenuates 3-Nitropropionic Acid-Induced Huntington’s-Like Symptoms

Directory of Open Access Journals (Sweden)

Minhee Jang

2013-01-01

Full Text Available Korean red ginseng (KRG possesses neuroprotective activity. However, the potential neuroprotective value of KRG for the striatal toxicity is largely unknown. We investigated whether KRG extract (KRGE could have a neuroprotective effect in a 3-nitropropionic acid- (3-NP induced (i.p. Huntington’s disease (HD model. KRGE (50, 100, and 250 mg/kg/day, p.o. was administrated 10 days before 3-NP injection (pre-administration, from the same time with 3-NP injection (co-administration, or from the peak point of neurological impairment by 3-NP injection (post-administration. Pre-administration of KRGE produced the greatest neuroprotective effect in this model. Pre-administration of KRGE significantly decreased 3-NP-induced neurological impairment, lethality, lesion area, and neuronal loss in the 3-NP-injected striatum. KRGE attenuated microglial activation and phosphorylation of mitogen-activated protein kinases (MAPKs and nuclear factor-kappa B (NF-κB signal pathway. KRGE also reduced the level of mRNA expression of tumor necrosis factor-alpha, interleukin- (IL- 1β, IL-6, inducible nitric oxide synthase, and OX-42. Interestingly, the intrathecal administration of SB203580 (a p38 inhibitor or PD98059 (an inhibitor of MAPK Kinase, MEK increased the survival rate in the 3-NP-induced HD model. Pre-administration of KRGE may effectively inhibit 3-NP-induced striatal toxicity via the inhibition of the phosphorylation of MAPKs and NF-κB pathways, indicating its therapeutic potential for suppressing Huntington’s-like symptoms.

Inhibition of Steptococcus mutans biofilm formation by extracts of Tenacibaculum sp. 20J, a bacterium with wide-spectrum quorum quenching activity

Science.gov (United States)

Muras, Andrea; Mayer, Celia; Romero, Manuel; Camino, Tamara; Ferrer, Maria D.; Mira, Alex; Otero, Ana

2018-01-01

ABSTRACT Background: Previous studies have suggested the quorum sensing signal AI-2 as a potential target to prevent the biofilm formation by Streptococcus mutans, a pathogen involved in tooth decay. Objective: To obtain inhibition of biofilm formation by S. mutans by extracts obtained from the marine bacterium Tenacibaculum sp. 20J interfering with the AI-2 quorum sensing system. Design: The AI-2 inhibitory activity was tested with the biosensors Vibrio harveyi BB170 and JMH597. S. mutans ATCC25175 biofilm formation was monitored using impedance real-time measurements with the xCELLigence system®, confocal laser microscopy, and the crystal violet quantification method. Results: The addition of the cell extract from Tenacibaculum sp. 20J reduced biofilm formation in S. mutans ATCC25175 by 40–50% compared to the control without significantly affecting growth. A decrease of almost 40% was also observed in S. oralis DSM20627 and S. dentisani 7747 biofilms. Conclusions: The ability of Tenacibaculum sp. 20J to interfere with AI-2 and inhibit biofilm formation in S. mutans was demonstrated. The results indicate that the inhibition of quorum sensing processes may constitute a suitable strategy for inhibiting dental plaque formation, although additional experiments using mixed biofilm models would be required. PMID:29410771

1/mQ corrections to form factors and extraction of |Vcb|

International Nuclear Information System (INIS)

Liu, J.; Chao, K.

1997-01-01

Form factors for 0 - →0 - and 0 - →1 - mesonic transitions in the heavy quark limit and the 1/m Q corrections are analyzed model independently within the Bethe-Salpeter (BS) formalism. The analysis shows that the BS formalism has spin-flavor symmetry in the heavy quark limit and respects Luke's theorem when the 1/m Q corrections are taken into account. All form factors for B→D (*) transitions beyond the zero recoil point are estimated in a relativistic constituent quark model based on the BS formalism. Using these form factors we calculate the branching ratios for the semileptonic decays B→D (*) l + ν l and extract the Cabibbo-Kobayashi-Maskawa matrix element |V cb |. We get |V cb |=0.042±0.003 which is consistent with the current world average. copyright 1997 The American Physical Society

Comprehensive study of buffer systems and local pH effects in electromembrane extraction

Czech Academy of Sciences Publication Activity Database

Restan, M. S.; Jensen, H.; Shen, X.; Huang, Ch.; Martinsen, O. G.; Kubáň, Pavel; Gjelstad, A.; Pedersen-Bjergaard, S.

2017-01-01

Roč. 984, SEP (2017), s. 116-123 ISSN 0003-2670 R&D Projects: GA ČR(CZ) GA16-09135S Institutional support: RVO:68081715 Keywords : electromembrane extraction * local pH changes * extraction efficiency Subject RIV: CB - Analytical Chemistry, Separation OBOR OECD: Analytical chemistry Impact factor: 4.950, year: 2016

Extraction of bitter acids from hops and hop products using pressurized solvent extraction (PSE)

Czech Academy of Sciences Publication Activity Database

Čulík, J.; Jurková, M.; Horák, T.; Čejka, P.; Kellner, V.; Dvořák, J.; Karásek, Pavel; Roth, Michal

2009-01-01

Roč. 115, č. 3 (2009), s. 220-225 ISSN 0046-9750 R&D Projects: GA ČR GA203/08/1536; GA MŠk 1M0570 Institutional research plan: CEZ:AV0Z40310501 Keywords : hops * bitter acids * pressurized solvent extraction Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 1.000, year: 2009

Deficient cortical face-sensitive N170 responses and basic visual processing in schizophrenia.

Science.gov (United States)

Maher, S; Mashhoon, Y; Ekstrom, T; Lukas, S; Chen, Y

2016-01-01

Face detection, an ability to identify a visual stimulus as a face, is impaired in patients with schizophrenia. It is unclear whether impaired face processing in this psychiatric disorder results from face-specific domains or stems from more basic visual domains. In this study, we examined cortical face-sensitive N170 response in schizophrenia, taking into account deficient basic visual contrast processing. We equalized visual contrast signals among patients (n=20) and controls (n=20) and between face and tree images, based on their individual perceptual capacities (determined using psychophysical methods). We measured N170, a putative temporal marker of face processing, during face detection and tree detection. In controls, N170 amplitudes were significantly greater for faces than trees across all three visual contrast levels tested (perceptual threshold, two times perceptual threshold and 100%). In patients, however, N170 amplitudes did not differ between faces and trees, indicating diminished face selectivity (indexed by the differential responses to face vs. tree). These results indicate a lack of face-selectivity in temporal responses of brain machinery putatively responsible for face processing in schizophrenia. This neuroimaging finding suggests that face-specific processing is compromised in this psychiatric disorder. Copyright © 2015 Elsevier B.V. All rights reserved.

The Sluggishness of Early-Stage Face Processing (N170 is Correlated with Negative and General Psychiatric Symptoms in Schizophrenia

Directory of Open Access Journals (Sweden)

Yingjun Zheng

2016-11-01

Full Text Available Patients with schizophrenia exhibit consistent abnormalities in face-evoked N170. However, the relation between face-specific N170 abnormalities in schizophrenic patients and schizophrenia clinical characters, which probably based on common neural mechanisms, is still rarely discovered. Using event-related potentials (ERPs recording in both schizophrenic patients and healthy controls, the amplitude and latency of N170 were recorded when participants were passively watching face and non-face (table pictures. The results showed a face-specific N170 latency sluggishness in schizophrenic patients, i.e., the N170 latencies of schizophrenic patients were significantly longer than those of healthy controls under both upright face and inverted face conditions. Importantly, the face-related N170 latencies of the left temporo-occipital electrodes (P7 and PO7 were positively correlated with negative symptoms and general psychiatric symptoms. Besides the analysis of latencies, the N170 amplitudes became weaker in schizophrenic patients under both inverted face and inverted table conditions, with a left hemisphere dominant. More interestingly, the FIEs (the difference of N170 amplitudes between upright and inverted faces were absent in schizophrenic patients, which suggested the abnormality of holistic face processing. These results above revealed a marked symptom-relevant neural sluggishness of face-specific processing in schizophrenic patients, supporting the demyelinating hypothesis of schizophrenia.

Indigofera suffruticosa Mill extracts up-regulate the expression of the π class of glutathione S-transferase and NAD(P)H: quinone oxidoreductase 1 in rat Clone 9 liver cells.

Science.gov (United States)

Chen, Chun-Chieh; Liu, Chin-San; Li, Chien-Chun; Tsai, Chia-Wen; Yao, Hsien-Tsung; Liu, Te-Chung; Chen, Haw-Wen; Chen, Pei-Yin; Wu, Yu-Ling; Lii, Chong-Kuei; Liu, Kai-Li

2013-09-01

Because induction of phase II detoxification enzyme is important for chemoprevention, we study the effects of Indigofera suffruticosa Mill, a medicinal herb, on the expression of π class of glutathione S-transferase (GSTP) and NAD(P)H: quinone oxidoreductase 1 (NQO1) in rat Clone 9 liver cells. Both water and ethanolic extracts of I. suffruticosa significantly increased the expression and enzyme activities of GSTP and NQO1. I. suffruticosa extracts up-regulated GSTP promoter activity and the binding affinity of nuclear factor erythroid 2-related factor 2 (Nrf2) with the GSTP enhancer I oligonucleotide. Moreover, I. suffruticosa extracts increased nuclear Nrf2 accumulation as well as ARE transcriptional activity. The level of phospho-ERK was augmented by I. suffruticosa extracts, and the ERK inhibitor PD98059 abolished the I. suffruticosa extract-induced ERK activation and GSTP and NQO-1 expression. Moreover, I. suffruticosa extracts, especially the ethanolic extract increased the glutathione level in mouse liver and red blood cells as well as Clone 9 liver cells. The efficacy of I. suffruticosa extracts in induction of phase II detoxification enzymes and glutathione content implies that I. suffruticosa could be considered as a potential chemopreventive agent. Copyright © 2013 Elsevier Ltd. All rights reserved.

78 FR 18624 - U.S. Extractive Industries Transparency Initiative Multi-Stakeholder Group (USEITI MSG) Advisory...

Science.gov (United States)

2013-03-27

... DEPARTMENT OF THE INTERIOR Office of the Secretary [Docket No. ONRR-2012-0003] U.S. Extractive Industries Transparency Initiative Multi- Stakeholder Group (USEITI MSG) Advisory Committee AGENCY: Policy..., teleconference and the May 1-2, 2013, meeting of the United States Extractive Industries Transparency Initiative...

42 CFR 415.170 - Conditions for payment on a fee schedule basis for physician services in a teaching setting.

Science.gov (United States)

2010-10-01

... physician services in a teaching setting. 415.170 Section 415.170 Public Health CENTERS FOR MEDICARE... BY PHYSICIANS IN PROVIDERS, SUPERVISING PHYSICIANS IN TEACHING SETTINGS, AND RESIDENTS IN CERTAIN SETTINGS Physician Services in Teaching Settings § 415.170 Conditions for payment on a fee schedule basis...

Effect of Date Extract on Growth of Mutans Streptococci, the Most Important Factor of Dental Caries

Directory of Open Access Journals (Sweden)

A Sayyedi

2007-01-01

Full Text Available ABSTRACT: Introduction & Objective:Dental caries is perhaps the most common bacterial infections in humans and Streptococcus Mutans is one of the most important factors in dental caries. Research has shown that some kind foods have an inhibitory effect on cariogenic factors of Mutans streptococci. The aim of this study was to investigate the effect of date extract on growth of Streptococcus Mutans. Methods & Materials: This experimental study was down at faculty of medicine, Yasuj university of medical sciences with collaborative of microbiology department of Shiraz university of medical sciences in 2005. In an In-vitro study, effect of date extract on growth of Mutans Streptococci was surveyed .After collecting of Streptococcus Mutans from dental caries those were cultured in different medium of date fruit, extract of date fruit and syrup of date with different concentrations. Results: Following 24 hours, Streptococcus mutans was grown in less concentration of date mediums and its grown was inhibited in more concentrations. Conclusion: With respect of inhibitory effect of date extract on growth of Streptococcus mutans,it might be introduced that date as a source of food has a preventive effect on dental caries.

Enhanced Charge Extraction of Li-Doped TiO2 for Efficient Thermal-Evaporated Sb2S3 Thin Film Solar Cells

Science.gov (United States)

Lan, Chunfeng; Luo, Jingting; Lan, Huabin; Fan, Bo; Peng, Huanxin; Zhao, Jun; Sun, Huibin; Zheng, Zhuanghao; Liang, Guangxing; Fan, Ping

2018-01-01

We provided a new method to improve the efficiency of Sb2S3 thin film solar cells. The TiO2 electron transport layers were doped by lithium to improve their charge extraction properties for the thermal-evaporated Sb2S3 solar cells. The Mott-Schottky curves suggested a change of energy band and faster charge transport in the Li-doped TiO2 films. Compared with the undoped TiO2, Li-doped mesoporous TiO2 dramatically improved the photo-voltaic performance of the thermal-evaporated Sb2S3 thin film solar cells, with the average power conversion efficiency (PCE) increasing from 1.79% to 4.03%, as well as the improved open-voltage (Voc), short-circuit current (Jsc) and fill factors. The best device based on Li-doped TiO2 achieved a power conversion efficiency up to 4.42% as well as a Voc of 0.645 V, which are the highest values among the reported thermal-evaporated Sb2S3 solar cells. This study showed that Li-doping on TiO2 can effectively enhance the charge extraction properties of electron transport layers, offering a new strategy to improve the efficiency of Sb2S3-based solar cells. PMID:29495612

Enhanced Charge Extraction of Li-Doped TiO2 for Efficient Thermal-Evaporated Sb2S3 Thin Film Solar Cells

Directory of Open Access Journals (Sweden)

Chunfeng Lan

2018-02-01

Full Text Available We provided a new method to improve the efficiency of Sb2S3 thin film solar cells. The TiO2 electron transport layers were doped by lithium to improve their charge extraction properties for the thermal-evaporated Sb2S3 solar cells. The Mott-Schottky curves suggested a change of energy band and faster charge transport in the Li-doped TiO2 films. Compared with the undoped TiO2, Li-doped mesoporous TiO2 dramatically improved the photo-voltaic performance of the thermal-evaporated Sb2S3 thin film solar cells, with the average power conversion efficiency (PCE increasing from 1.79% to 4.03%, as well as the improved open-voltage (Voc, short-circuit current (Jsc and fill factors. The best device based on Li-doped TiO2 achieved a power conversion efficiency up to 4.42% as well as a Voc of 0.645 V, which are the highest values among the reported thermal-evaporated Sb2S3 solar cells. This study showed that Li-doping on TiO2 can effectively enhance the charge extraction properties of electron transport layers, offering a new strategy to improve the efficiency of Sb2S3-based solar cells.

Extraction of depth-dependent perturbation factors for silicon diodes using a plastic scintillation detector.

Science.gov (United States)

Lacroix, Frederic; Guillot, Mathieu; McEwen, Malcolm; Gingras, Luc; Beaulieu, Luc

2011-10-01

This work presents the experimental extraction of the perturbation factor in megavoltage electron beams for three models of silicon diodes (IBA Dosimetry, EFD and SFD, and the PTW 60012 unshielded) using a plastic scintillation detector (PSD). The authors used a single scanning PSD mounted on a high-precision scanning tank to measure depth-dose curves in 6-, 12-, and 18-MeV clinical electron beams. They also measured depth-dose curves using the IBA Dosimetry, EFD and SFD, and the PTW 60012 unshielded diodes. The authors used the depth-dose curves measured with the PSD as a perturbation-free reference to extract the perturbation factors of the diodes. The authors found that the perturbation factors for the diodes increased substantially with depth, especially for low-energy electron beams. The experimental results show the same trend as published Monte Carlo simulation results for the EFD diode; however, the perturbations measured experimentally were greater. They found that using an effective point of measurement (EPOM) placed slightly away from the source reduced the variation of perturbation factors with depth and that the optimal EPOM appears to be energy dependent. The manufacturer recommended EPOM appears to be incorrect at low electron energy (6 MeV). In addition, the perturbation factors for diodes may be greater than predicted by Monte Carlo simulations.

Extraction of depth-dependent perturbation factors for silicon diodes using a plastic scintillation detector

International Nuclear Information System (INIS)

Lacroix, Frederic; Guillot, Mathieu; McEwen, Malcolm; Gingras, Luc; Beaulieu, Luc

2011-01-01

Purpose: This work presents the experimental extraction of the perturbation factor in megavoltage electron beams for three models of silicon diodes (IBA Dosimetry, EFD and SFD, and the PTW 60012 unshielded) using a plastic scintillation detector (PSD). Methods: The authors used a single scanning PSD mounted on a high-precision scanning tank to measure depth-dose curves in 6-, 12-, and 18-MeV clinical electron beams. They also measured depth-dose curves using the IBA Dosimetry, EFD and SFD, and the PTW 60012 unshielded diodes. The authors used the depth-dose curves measured with the PSD as a perturbation-free reference to extract the perturbation factors of the diodes. Results: The authors found that the perturbation factors for the diodes increased substantially with depth, especially for low-energy electron beams. The experimental results show the same trend as published Monte Carlo simulation results for the EFD diode; however, the perturbations measured experimentally were greater. They found that using an effective point of measurement (EPOM) placed slightly away from the source reduced the variation of perturbation factors with depth and that the optimal EPOM appears to be energy dependent. Conclusions: The manufacturer recommended EPOM appears to be incorrect at low electron energy (6 MeV). In addition, the perturbation factors for diodes may be greater than predicted by Monte Carlo simulations.

Identification of boosted, hadronically decaying W bosons and comparisons with ATLAS data taken at √s=8 TeV

Czech Academy of Sciences Publication Activity Database

Aad, G.; Abbott, B.; Abdallah, J.; Chudoba, Jiří; Havránek, Miroslav; Hejbal, Jiří; Jakoubek, Tomáš; Kepka, Oldřich; Kupčo, Alexander; Kůs, Vlastimil; Lokajíček, Miloš; Lysák, Roman; Marčišovský, Michal; Mikeštíková, Marcela; Němeček, Stanislav; Penc, Ondřej; Šícho, Petr; Staroba, Pavel; Svatoš, Michal; Taševský, Marek; Vrba, Václav

2016-01-01

Roč. 76, č. 3 (2016), s. 1-70, č. článku 154. ISSN 1434-6044 Institutional support: RVO:68378271 Keywords : CERN LHC Coll * background * structure * ATLAS * mass resolution Subject RIV: BF - Elementary Particles and High Energy Physics Impact factor: 5.331, year: 2016

14 CFR 170.23 - LORAN-C establishment criteria.

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2010-01-01

... value of benefits associated with the LORAN-C approach equals or exceeds the estimated costs (benefit-cost ratio equals or exceeds one). As defined in § 170.3 of this part, the benefit-cost ratio is the ratio of the present value of the LORAN-C life-cycle benefits (PVB) to the present value of LORAN-C life...

17 CFR 170.10 - Proficiency examinations (sections 4p and 17(p) of the Act).

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2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Proficiency examinations (sections 4p and 17(p) of the Act). 170.10 Section 170.10 Commodity and Securities Exchanges COMMODITY... examinations (sections 4p and 17(p) of the Act). A futures association may prescribe different training...

Comparative biochemical and computational study of the role of naturally occurring mutations at Ambler positions 104 and 170 in GES β-lactamases.

Science.gov (United States)

Kotsakis, Stathis D; Miriagou, Vivi; Tzelepi, Eva; Tzouvelekis, Leonidas S

2010-11-01

In GES-type β-lactamases, positions 104 and 170 are occupied by Glu or Lys and by Gly, Asn, or Ser, respectively. Previous studies have indicated an important role of these amino acids in the interaction with β-lactams, although their precise role, especially that of residue 104, remains uncertain. In this study, we constructed GES-1 (Glu104, Gly170), GES-2 (Glu104, Asn170), GES-5 (Glu104, Ser170), GES-6 (Lys104, Ser170), GES-7 (Lys104, Gly170), and GES-13 (Lys104, Asn170) by site-specific mutagenesis and compared their hydrolytic properties. Isogenic comparisons of β-lactam resistance levels conferred by these GES variants were also performed. Data indicated the following patterns: (i) Lys104-containing enzymes exhibited enhanced hydrolysis of oxyimino-cephalosporins and reduced efficiency against imipenem in relation to enzymes possessing Glu104, (ii) Asn170-containing enzymes showed reduced hydrolysis rates of penicillins and older cephalosporins, (iii) Ser170 enabled GES to hydrolyze cefoxitin efficiently, and (iv) Asn170 and Ser170 increased the carbapenemase character of GES enzymes but reduced their activity against ceftazidime. Molecular dynamic simulations of GES apoenzyme models, as well as construction of GES structures complexed with cefoxitin and an achiral ceftazidime-like boronic acid, provided insights into the catalytic behavior of the studied mutants. There were indications that an increased stability of the hydrogen bonding network of Glu166-Lys73-Ser70 and an altered positioning of Trp105 correlated with the substrate spectra, especially with acylation of GES by imipenem. Furthermore, likely effects of Ser170 on GES interactions with cefoxitin and of Lys104 on interactions with oxyimino-cephalosporins were revealed. Overall, the data unveiled the importance of residues 104 and 170 in the function of GES enzymes.

Multiclass pesticide determination in olives and their processing factors in olive oil: comparison of different olive oil extraction systems.

Science.gov (United States)

Amvrazi, Elpiniki G; Albanis, Triantafyllos A

2008-07-23

The processing factors (pesticide concentration found in olive oil/pesticide concentration found in olives) of azinphos methyl, chlorpyrifos, lambda-cyhalothrin, deltamethrin, diazinon, dimethoate, endosulfan, and fenthion were determined in olive oil production process in various laboratory-scale olive oil extractions based on three- or two-phase centrifugation systems in comparison with samples collected during olive oil extractions in conventional olive mills located at different olive oil production areas in Greece. Pesticide analyses were performed using a multiresidue method developed in our laboratory for the determination of different insecticides and herbicides in olive oil by solid-phase extraction techniques coupled to gas chromatography detection (electron capture detection and nitrogen phosphorus detection), optimized, and validated for olive fruits sample preparation. Processing factors were found to vary among the different pesticides studied. Water addition in the oil extraction procedure (as in a three-phase centrifugation system) was found to decrease the processing factors of dimethoate, alpha-endosulfan, diazinon, and chlorpyrifos, whereas those of fenthion, azinphos methyl, beta-endosulfan, lambda-cyhalothrin, and deltamethrin residues were not affected. The water content of olives processed was found to proportionally affect pesticide processing factors. Fenthion sulfoxide and endosulfan sulfate were the major metabolites of fenthion and endosulfan, respectively, that were detected in laboratory-produced olive oils, but only the concentration of fenthion sulfoxide was found to increase with the increase of water addition in the olive oil extraction process.

Conductivity, impurity profile, and cytotoxicity of solvent-extracted polyaniline

Czech Academy of Sciences Publication Activity Database

Kašpárková, V.; Humpolíček, P.; Stejskal, Jaroslav; Kopecká, J.; Kuceková, Z.; Moučka, R.

2016-01-01

Roč. 27, č. 2 (2016), s. 156-161 ISSN 1042-7147 R&D Projects: GA ČR(CZ) GA13-08944S Institutional support: RVO:61389013 Keywords : polyaniline * Soxhlet extraction * purification Subject RIV: CD - Macromolecular Chemistry Impact factor: 1.907, year: 2016

Recoil-distance lifetime measurements of the ground-state band in 164Dy, 170Er, and 174Yb

International Nuclear Information System (INIS)

Sie, S.H.; Gebbie, D.W.

1977-06-01

Mean-lives of the 4 + , 6 + and 8 + levels of the ground-state band in 164 Dy, 170 Er and 174 Yb have been measured by the recoil-distance technique following multiple Coulomb excitation with 32 S projectiles of energy 120-140 MeV. The gamma-rays were detected in coincidence with backscattered particles. The results are compared with theoretical predictions of the adiabatic rotor model. The 6 + and 8 + lifetimes in 164 Dy are found to correspond to a slight reduction in B(E2) values over the rotational model prediction, while for for the 4 + state a 12% reduction was observed. In 170 Er and 174 Yb the lifetimes are consistent with rotational model predictions with a slight enhancement of B(E2) values at higher spins. Comparison with other results from Doppler broadened lineshape analysis confirms the need to adjust the electronic stopping powers of Northcliffe and Schilling in the lineshape calculations. (Author)

78 FR 50437 - U.S. Extractive Industries Transparency Initiative Multi-Stakeholder Group (USEITI MSG) Advisory...

Science.gov (United States)

2013-08-19

... DEPARTMENT OF THE INTERIOR Office of the Secretary [Docket No. ONRR-2012-0003; DS63600000 DR2PS0000.PX8000 134D0102R2] U.S. Extractive Industries Transparency Initiative Multi- Stakeholder Group...: This notice announces the next three meetings of the United States Extractive Industries Transparency...

78 FR 60304 - U.S. Extractive Industries Transparency Initiative Multi-Stakeholder Group (USEITI MSG) Advisory...

Science.gov (United States)

2013-10-01

... DEPARTMENT OF THE INTERIOR Office of the Secretary [Docket No. ONRR-2012-0003; DS63600000 DR2PS0000.PX8000 134D0102R2] U.S. Extractive Industries Transparency Initiative Multi- Stakeholder Group...: This notice announces the meeting date change of the United States Extractive Industries Transparency...

Factores de riesgo del recién nacido macrosómico

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Irka Ballesté López

2004-03-01

Full Text Available Para reconocer algunos factores asociados a la macrosomía, se realizó un estudio tipo caso control. Los casos estaban formados por 170 neonatos con 4 000 g y más y los controles por 260 recién nacidos con peso entre 3 000 y 3 999 g. Se evaluó un grupo de factores de riesgo materno, antecedentes obstétricos, relacionados con el parto y con el recién nacido. Se estimó el riesgo relativo de cada factor de asociarse con la macrosomía mediante la razón de productos cruzados (OR y se evaluó la significación estadística mediante el intervalo de confianza del 95 % (IC-95 % y mediante la prueba de chi-cuadrado (X2 o la prueba de Fisher según conviniera en cada caso.Se halló asociado con la macrosomía, la edad materna mayor de 30 años (OR = 4, la edad gestacional mayor de 42 semanas (OR = 5,8, la talla materna mayor de 1,70 cm (OR= 6,6, antecedente de hijo macrosómico anterior (OR = 5,7, la diabetes familiar (OR = 3,6 y el sexo masculino (OR = 2,8. No aumentó el riesgo de cesáreas ni de Apgar bajo.A case-control study was conducted to recognize some factors associated with macrosomia. The cases were 170 neonates with 4 000 g and over, whereas the controls were 260 newborn infants with a weight that ranged between 3 000 and 3 999 g. A group of maternal risk factors, obstetric history, related to delivery and to the newborn infant were evaluated. The relative risk of each factor for associating with macrosomy was estimated by the cross product ratio (OR. The statistical significance was evaluated by the confidence interval of 95 % (CI-95 % and by the Chi square test (X2 or the Fisher test according to each case. Maternal age over 30 (OR=4, gestational age over 42 weeks (OR=5.8, maternal height over 1.70 cm (R=6.6, history of previous macrosomic children (OR=5.7, family diabetes (OR=3.6 and the male sex (OR=2.8 were associated with macrosomia. No increase was observed in the risk of cesarean section, or low Apgar score.

Neuroprotective Effects of Herbal Extract (Rosa canina, Tanacetum vulgare and Urtica dioica) on Rat Model of Sporadic Alzheimer’s Disease

Science.gov (United States)

Daneshmand, Parvaneh; Saliminejad, Kioomars; Dehghan Shasaltaneh, Marzieh; Kamali, Koorosh; Riazi, Gholam Hossein; Nazari, Reza; Azimzadeh, Pedram; Khorram Khorshid, Hamid Reza

2016-01-01

Background: Sporadic Alzheimer’s Disease (SAD) is caused by genetic risk factors, aging and oxidative stresses. The herbal extract of Rosa canina (R. canina), Tanacetum vulgare (T. vulgare) and Urtica dioica (U. dioica) has a beneficial role in aging, as an anti-inflammatory and anti-oxidative agent. In this study, the neuroprotective effects of this herbal extract in the rat model of SAD was investigated. Methods: The rats were divided into control, sham, model, herbal extract -treated and ethanol-treated groups. Drug interventions were started on the 21st day after modeling and each treatment group was given the drugs by intraperitoneal (I.P.) route for 21 days. The expression levels of the five important genes for pathogenesis of SAD including Syp, Psen1, Mapk3, Map2 and Tnf-α were measured by qPCR between the hippocampi of SAD model which were treated by this herbal extract and control groups. The Morris Water Maze was adapted to test spatial learning and memory ability of the rats. Results: Treatment of the rat model of SAD with herbal extract induced a significant change in expression of Syp (p=0.001) and Psen1 (p=0.029). In Morris Water Maze, significant changes in spatial learning seen in the rat model group were improved in herbal-treated group. Conclusion: This herbal extract could have anti-dementia properties and improve spatial learning and memory in SAD rat model. PMID:27563424

Membrane extraction instead of solvent extraction - what does it give

International Nuclear Information System (INIS)

Macasek, F.

1989-01-01

Membrane extraction, i.e. separation in double-emulsion systems, is analyzed theoretically as a three-phase distribution process. Its efficiency is evaluated from the point of view of chemical equilibria and diffusion transport kinetics. The main advantages of membrane extraction as compared with solvent extraction are in higher yields (for preconcentration) and higher capacity for recovery of solutes. A pertraction factor and multiplication factor were defined. They are convenient parameters for numerical characterization of solute distribution, system capacity, process economics, and separation kinetics (both at a linear and non-linear extraction isotherm). 17 refs.; 4 figs

48 CFR 1446.170 - Government-Industry Data Exchange Program (GIDEP).

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2010-10-01

... THE INTERIOR CONTRACT MANAGEMENT QUALITY ASSURANCE General 1446.170 Government-Industry Data Exchange..., metrology, product information, and reliability-maintain ability data on products, components (including construction materials), manufacturing processes, environmental issues associated with those manufacturing...

27 CFR 24.170 - Measuring devices and testing instruments.

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2010-04-01

... wine, spirits, volatile fruit-flavor concentrate, or materials received and used in the production or treatment of wine. Where winemaking materials or other materials used in the treatment of wine are used... AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS WINE Construction and Equipment § 24.170...

42 CFR 456.170 - Medical, psychiatric, and social evaluations.

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2010-10-01

... 42 Public Health 4 2010-10-01 2010-10-01 false Medical, psychiatric, and social evaluations. 456... Hospitals Medical, Psychiatric, and Social Evaluations and Admission Review § 456.170 Medical, psychiatric... recipient's need for care in the hospital; and appropriate professional personnel must make a psychiatric...

Evaluation of Saponin Extract from Vitex doniana and Pentaclethra macrophylla for Antibacterial Activity

Directory of Open Access Journals (Sweden)

Nneoma E. Akaniro-Ejim

2016-06-01

Full Text Available Saponins are pharmacologically active compounds that have been shown to ameliorate abnormal physiological processes and be aptly applied in folklore for the treatment of maladies occasioned by infectious agents. Consequently, saponins from Vitex doniana and Pentaclethra macrophylla were evaluated for antibacterial properties, as these herbs are used in folk medicine. Dried pulverized plant materials were defatted, and solvents with varying polarity were applied at varying ratios for the extraction of saponins. Phyto-chemistry was in accordance with standard methods, while an antibacterial assay was made through the agar well diffusion and micro broth dilution techniques. Phytochemical quantitation showed high concentrations of tannins, 231 ± 0.6 CE/g, and saponins, 58% from V. doniana. Similarly, P. macrophylla stem bark extract also showed high concentrations of tannins, 309 ± 2.42 CE/g, alkaloids, 71% ± 0.5%, and saponins, 87% ± 3.4%. The ethanol extracts of V. doniana inhibited the growth of Staphylococcus aureus (ATCC 11775 and a clinical strain with inhibition zone ranges of 15.5 ± 2.12 to 7.0 ± 0.0 (mm against leaf extracts and 20.0 ± 1.41 to 7.0 ± 0.0 (mm against stem bark extracts. Conversely, saponin extract from V. doniana showed a broad spectrum of activity, as it inhibited both Gram-negative and -positive test strains, E. coli clinical strain (20.0 ± 1.41 mm, P. aeruginosa clinical strain (18.5 ± 0.71 mm, E. coli ATCC 11775 (17.0 ± 0 mm, and S. aureus clinical strain (13.0 ± 1.41 mm. However, a broad spectrum was similarly achieved with P. macrophylla extracts, as all test bacteria genus was susceptible. Saponin fractions showed a high potency and broad spectrum antibacterial activity and thus a validation of the folklore applications and the potential for use as a drug or drug scaffold.

Determination of six phthalates in polypropylene consumer products by sonication-assisted extraction/ GC-MS methods

International Nuclear Information System (INIS)

Wei, Chong Kian; Fung, Loke Chui; Pang, Michelle

2011-01-01

Studies on determination of six kinds of phthalates, for example dimethyl phthalate (DMP), diethyl phthalate (DEP), dibutyl phthalate (DBP), benzyl butyl phthalate (BBP), di-(2-ethylhexyl) phthalate (DEHP), and di-n-octyl phthalate (DnOP), in three kinds of plastic containers for food use, including food container, instant noodle cup and snack container, by gas chromatography in combination with mass spectrometry detector (GC-MS) in electronic ionization mode with selected-ion monitoring (SIM) acquisition method (GC-MS(EI-SIM)) have been carried out. Extraction, clean-up and analysis methods have been developed and optimized. Determination of samples were performed after sonication-assisted extraction with 1:9 toluene and dichloromethane, clean-up with Bio-Beads S-X8 gel-permeation column and analyzed by GC-MS methods. The characteristic ions, 163, 194 for DMP; 149, 177, 222 for DEP; 149, 233, 251 for DBP; 91, 149, 206 for BBP; 149, 176, 193 for DEHP; 149, 167, 279 for DNOP were chosen for quantitative studies. These techniques are possible to detect phthalates at the level of 1-70 mg/ kg. The overall recoveries were 79.2-91.1 % with relative standard deviation (R.S.D.) values at 3.1-11.3 %. Only DEHP was detected in the studied samples. (author)

Modeling of the Kinetics of Supercritical Fluid Extraction of Lipids from Microalgae with Emphasis on Extract Desorption.

Czech Academy of Sciences Publication Activity Database

Sovová, Helena; Nobre, B.P.; Palavra, A.

2016-01-01

Roč. 9, č. 6 (2016), s. 423-441 ISSN 1996-1944 Grant - others:FCT(PT) UID/QUI/00100/2013; FCT(PT) SFRH/BPD/100283/2014 Institutional support: RVO:67985858 Keywords : microalgae * supercritical extraction * kinetics Subject RIV: CI - Industrial Chemistry, Chemical Engineering Impact factor: 2.654, year: 2016

Age-specific inhalation radiation dose commitment factors for selected radionuclides

International Nuclear Information System (INIS)

Strenge, D.L.; Peloquin, R.A.; Baker, D.A.

1982-08-01

Inhalation dose commitment factors are presented for selected radionuclides for exposure of individuals in four age groups: infant, child, teen and adult. Radionuclides considered are 35 S, 36 Cl, 45 Ca, 67 Ga, 75 Se, 85 Sr, 109 Cd, 113 Sn, 125 I, 133 Ba, 170 Tm, 169 Yb, 182 Ta, 192 Ir, 198 Au, 201 Tl, 204 Tl, and 236 Pu. The calculational method is based on the human metabolic model of ICRP as defined in Publication 2 (ICRP 1959) and as used in previous age-specific dose factor calculations by Hoenes and Soldat (1977). Dose commitment factors are presented for the following organs of reference: total body, bone, liver, kidney, thyroid, lung and lower large intestine

Clinical assessment of bone quality of human extraction sockets after conversion with growth factors.

Science.gov (United States)

Ntounis, Athanasios; Geurs, Nico; Vassilopoulos, Philip; Reddy, Michael

2015-01-01

The study was conducted to evaluate the effect of mineralized freeze-dried bone allograft (FDBA), alone or in combination with growth factors in extraction sockets, on subjective assessment of bone quality during implant placement. Forty-one patients whose treatment plan involved extraction of anterior or premolar teeth were randomized into four groups: Group 1, collagen plug (control); Group 2, FDBA/β-tricalcium phosphate (β-TCP)/collagen plug; Group 3, FDBA/β-TCP/platelet-rich plasma (PRP)/collagen plug; Group 4, FDBA/β-TCP/recombinant human platelet-derived growth factor BB (rhPDGF-BB)/collagen plug. After 8 weeks of healing, implants were placed. The clinicians assessed bone quality according to the Misch classification. A benchtop calibration exercise test was conducted to evaluate agreement and accuracy of operators in recognizing different bone qualities. Differences were analyzed using one-way analysis of variance (ANOVA) or chi-square tests for continuous and categorical data. Pairwise comparisons were tested using least squares means (LS means). Spearman correlation coefficients were used to evaluate the relationship of bone growth with potential confounders. P .05). Inclusion of bone grafting is associated with a shift from D4 quality to D3 quality bone. Inclusion of PRP in bone grafting eliminates the incidence of D4 bone, establishing D3 and D2 quality bone as prevalent (56% vs. 42%, respectively). Inclusion of rhPDGF-BB and β-TCP in combination with the bone grafting has the same effect, although D2 quality is less prevalent. When compared to sockets grafted with FDBA/β-TCP/collagen plug alone, the sockets with growth factors demonstrated fewer residual bone graft particles. (1) Inclusion of bone grafting enhanced bone quality as assessed during implant placement. (2) Overall inclusion of PRP and rhPDGF-BB enhanced subjective bone quality, eliminating incidence of D4 quality in human extraction sockets. (3) The use of PRP or rhPDGF-BB may

Flotation extraction of tributyl phosphate from s olutions

International Nuclear Information System (INIS)

Skrylev, L.D.; Tkachenko, N.V.; Sazonova, V.F.

1983-01-01

Results of investigations, conducted for revealing the possibility of flotation extraction of emulsificated and actually dissolved extractants, tributyl phosphate (TBP) in particular, are given. The possibility of flotation extraction of emulsificated and actually dissolved TBP by its non-reagent flotation was established experimeptally. It was also established that the kinetics of flotation TBP extraction is described by the equation, similar to the reaction equation of the first order. The process of non-reagent TBP flotation proceeds most successfully in pH=6.5-7.5 range

Subcritical Water Extraction of Monosaccharides from Oil Palm Fronds Hemicelluloses

International Nuclear Information System (INIS)

Norsyabilah, R.; Hanim, S.S.; Norsuhaila, M.H.; Noraishah, A.K.; Siti Kartina

2013-01-01

Oil palm plantations in Malaysia generate more than 36 million tones of pruned and felled oil palm fronds (OPF) and are generally considered as waste. The composition of monosaccharide in oil palm frond can be extracted using hydrothermal treatment for useful applications. The objectives of this study were to quantify the yield of monosaccharides at various reaction conditions; temperature 170 to 200 degree Celsius, pressure from 500 psi to 800 psi, reaction time from 5 to 15 min using subcritical water extraction and to determine the composition of oil palm frond hemicelluloses at optimum condition. The monosaccharides composition of oil palm frond hemicelluloses were analysed using High Performance Liquid Chromatography (HPLC). The highest yield of monosaccharides can be extracted from OPF at temperature of 190 degree Celsius, pressure of 600 psi and 10 min of contact time which is xylose the most abundant composition (11.79 %) followed with arabinose (2.82 %), glucose (0.61 %) and mannose (0.66 %). (author)

Nouvelles géographies des activités extractives 

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Géraud Magrin

2011-10-01

Full Text Available Après un premier dossier consacré aux mines d’Afrique de l’Ouest, EchoGéo prolonge ici l’exploration de la géographie contemporaine des activités extractives en s’intéressant à de nouveaux espaces (Burkina Faso, Guyane, Gabon, Golfe de Guinée ; Asie du Sud et Afrique orientale et à des ressources variées (or, fer, pétrole, gemmes. Les cinq textes qui composent le présent dossier invitent à l’exploration de lieux, de stratégies d’acteurs, de relations entre acteurs et entre acteurs et milieu...

Effects of Extraction Solvents on the Quantification of Free Amino Acids in Lyophilised Brewer’s Yeast

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Andreea STĂNILĂ

2018-05-01

Full Text Available The aim of this work was to test some solvents in order to improve the free amino acids extraction from lyophilised brewer’s yeast. The brewer’ yeast was treated with four types of extraction solvents: Solvent I – acetonitrile 25%/HCl 0.01M (ACN; Solvent II – ethanol 80%; solvent III – HCl 0.05M/deionized water (1/1 volume; Solvent IV – HCl 0.05M/ethanol 80% (1/1 volume. The supernatants were analysed by HPLC-DAD-ESI-MS method. Acetonitrile provided the less quantities and number of amino acids extracted due to its weaker polarity. Solvent II and IV (ethanol, respectively acidified ethanol, which have an increased polarity, extracted 15 amino acids due to the addition of HCl in solvent IV. Solvent III (acidified water proved to be the best extraction solvent for the amino acids from brewer’s yeast providing the separation of 17 compounds: GLN, ASN, SER, GLY, ALA, ORN, PRO, HIS, LYS, GLU, TRP, LEU, PHE, ILE, AAA, HPHE, TYR.

45 CFR 170.460 - Good standing as an ONC-ATCB.

Science.gov (United States)

2010-10-01

....460 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.460 Good standing...

40 CFR 267.170 - Does this subpart apply to me?

Science.gov (United States)

2010-07-01

... PERMIT Use and Management of Containers § 267.170 Does this subpart apply to me? This subpart applies to you if you own or operate a facility that treats or stores hazardous waste in containers under a 40...

Semi-automated set-up for exhaustive micro-electromembrane extractions of basic drugs from biological fluids

Czech Academy of Sciences Publication Activity Database

Dvořák, Miloš; Seip, K. F.; Pedersen-Bjergaard, S.; Kubáň, Pavel

2018-01-01

Roč. 1005, APR (2018), s. 34-42 ISSN 0003-2670 R&D Projects: GA ČR(CZ) GA16-09135S Institutional support: RVO:68081715 Keywords : electromembrane extraction * exhaustive extraction * automation Subject RIV: CB - Analytical Chemistry, Separation OBOR OECD: Analytical chemistry Impact factor: 4.950, year: 2016

Factors influencing the chemical extractability of 241Am from a contaminated soil

International Nuclear Information System (INIS)

Nishita, H.; Hamilton, M.

1976-01-01

Factors influencing the extractability of 241 Am from an artificially contaminated soil were investigated. This was done with an equilibrium batch technique using CH 3 COOH-NH 4 OH and HNO 3 -NaOH extracting systems. The influence of several soil components was determined indirectly by selectively removing them from the soil. The effect of water- and HCl-soluble salts and organic matter on 241 Am extractability was small. The most marked effect was due to the soil organic fraction that was not water- or HCl-soluble. This organic fraction was influential under both low and high pH conditions, but its influence was particularly marked under low pH conditions. The free iron-oxides had an appreciable effect under low pH conditions, but no observable effect in the high pH range. Though to a lesser extent, the free silica and alumina, amorphous alumino-silicate, and possibly residual organic matter also showed some influence. These results provide some implications on the conditions that influence the movement of 241 Am in soils and its availability to plants. A review of the literature on the behavior of Am in soils is included

Eritrodermia: estudo clínico-laboratorial e histopatológico de 170 casos Erythroderma: a clinico-laboratorial and histopathological study of 170 cases

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Nurimar C. Fernandes

2008-12-01

Full Text Available FUNDAMENTOS - A dermatite esfoliativa/eritrodermia é síndrome rara e grave, de etiologia freqüentemente desconhecida. A hospitalização é necessária para avaliação inicial e tratamento. OBJETIVO - Determinar o perfil clínico, laboratorial e histopatológico dos eritrodérmicos internados no HUCFF-UFRJ. MÉTODOS - No período de 1990 a 2007, 170 casos foram submetidos a hemograma, velocidade de hemossedimentação, bioquímica do sangue, provas de função hepática, proteínas totais e frações, pesquisa de células de Sézary no esfregaço de sangue periférico, radiografia de campos pleuropulmonares e biópsia de pele em três locais. RESULTADOS - Entre 92 homens e 78 mulheres, na faixa de 30 a 80 anos, identificaram-se 99 casos (58,23% com dermatoses preexistentes; 37 (21,77% com farmacodermias; 18 (10,58% com linfomas cutâneos de células T e 16 (9,4% de causa indeterminada. Calafrios, prurido, linfonodomegalias e edema de membros inferiores destacaram-se dentre sinais e sintomas. O perfil laboratorial consistiu de aumento da VHS, eosinofilia, leucocitose, linfocitose e anemia. No grupo de etiologia indeterminada, dois padrões histológicos emergiram: dermatite psoriasiforme e dermatite inespecífica. CONCLUSÃO - A psoríase foi a causa mais freqüente; três biópsias de pele simultâneas podem aumentar a acurácia do diagnóstico histopatológico.BACKGROUND - Exfoliative dermatitis (erythroderma is a rare, severe syndrome, frequently of unknown etiology. The hospitalization is required for the initial evaluation and to establish the treatment. OBJECTIVE - to determine the clinical, laboratorial and histologic profile of erythrodermic inpatients at HUCFF-UFRJ. METHODS - in the period 1990-2007, 170 patients were submitted to complete blood cell count, erythrocyte sedimentation rate, blood urea, glucose and creatinine, liver function tests, proteinogram, circulating Sézary cells count, chest X Rays and skin biopsy of three

Effects of a cyanobacterial extract containing-anatoxin-a(s on the cardiac rhythm of Leurolestes circunvagans

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Vania Rodríguez

2012-05-01

Full Text Available This work presents the effects of an anatoxin-a(s-containing extract on a cockroach semi-isolated heart preparation and the results supporting the extract’s biological activity on acetylcholinesterase (purified from ell. The presence of the toxin in cyanobacterial strains Anabaena spiroides (ITEP-024, ITEP-025 and ITEP-026 isolated from the Tapacurá reservoir in Pernambuco, Brazil, was confirmed by means of liquid chromatography coupled to an ion-trap mass spectrometer. The anticholinesterase activity was assessed biochemically by the Ellman test and was confirmed by measuring the cockroach’s heart rate. The concentration of the extract containing the tested anatoxin-a(s (antx-a(s (10, 16 and 100 μg.μL-1 inhibited the eel acetylcholinesterase (AChE by more than 90%. The cockroach cardiac frequency increased by a maximum of about 20% within 29 min after the addition of 2.5x10³ μg of extract containing antxa (s.g-1 bw (n=9, p<0.05. Our results strongly indicate that antx-a(s is capable of exerting biological effects on cockroach, indicating that more research might be conducted to determine its role in the environment, especially on insects.

Chinese Characters Elicit Face-Like N170 Inversion Effects

Science.gov (United States)

Wang, Man-Ying; Kuo, Bo-Cheng; Cheng, Shih-Kuen

2011-01-01

Recognition of both faces and Chinese characters is commonly believed to rely on configural information. While faces typically exhibit behavioral and N170 inversion effects that differ from non-face stimuli (Rossion, Joyce, Cottrell, & Tarr, 2003), the current study examined whether a similar reliance on configural processing may result in similar…

Laser-assisted lead extraction: the European experience.

Science.gov (United States)

Kennergren, C; Bucknall, C A; Butter, C; Charles, R; Fuhrer, J; Grosfeld, M; Tavernier, R; Morgado, T B; Mortensen, P; Paul, V; Richter, P; Schwartz, T; Wellens, F

2007-08-01

The aim of this study is to investigate the safety and effectiveness of Excimer laser-assisted lead extraction in Europe. The final European multi-centre study experience is presented. The Excimer is a cool cutting laser (50 degrees C) with a wavelength of 308 nm. The energy is emitted from the tip of a flexible sheath and is absorbed by proteins and lipids, 64% of the energy is absorbed at a tissue depth of 0.06 mm. The sheath is positioned over the lead, and the fibrosis surrounding the lead is vaporized while advancing the sheath without damaging other leads. From August 1996 to March 2001, 383 leads (170 atrial, 213 ventricular) in 292 patients (mean age 61.6 years, range 13-96) were extracted at 14 European centres. Mean implantation time was 74 months (3-358). Most frequent indications were pocket infection (26%), non-functional leads (21%), patient morbidity (21%), septicaemia or endocarditis (14%), erosion (5%), and lead interference (8%). Median extraction time was 15 min (1-300). Complete extraction was achieved in 90.9% of the leads and partial extraction in 3.4%. Extraction failed in 5.7% of the leads. Major complications = perforations caused 10/22 (3.4/5.7%) of the failures. Most partially extracted patients were considered clinically successful, as only minor lead parts without clinical significance were left. Femoral non-laser technique was used to remove 8/12 of the non-complication failures. The total complication rate, including five minor complications (1.7%), was 5.1%. No in-hospital mortality occurred. Pacing and implantable cardioverter-defibrillator leads can safely, effectively, and predictably be extracted. Open-heart extractions can be limited to special cases. The results indicate that the traditional policy of abandoning redundant leads, instead of removing them, may be obsolete in many patients.

Factors associated with strabismus after cataract extraction and primary intraocular lens implantation in congenital cataracts

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Soo Jung Lee

2014-06-01

Full Text Available AIM: To evaluate factors associated with the development of strabismus after cataract extraction and primary intraocular lens implantation.METHODS: The medical records of 122 patients, aged 1.5mo to 9y, who had undergone cataract extraction with primary intraocular lens implantation between January 1993 and August 2011 were reviewed. Fourteen patients (17 eyes with strabismus before cataract surgery were excluded. Patients were divided into those with congenital bilateral cataracts (64 patients, 128 eyes and those with unilateral cataracts (44 patients, 44 eyes. The associations between the development of strabismus and age at cataract surgery, pre- and post-cataract extraction corrected distance visual acuity (CDVA, interocular CDVA difference, nystagmus, surgical method, and secondary cataract were evaluated.RESULTS: Factors significantly associated with the development of strabismus included age at cataract surgery (≤1y, preoperative mean CDVA ≤20/100, presence of nystagmus in the bilateral cataract group and postoperative interocular CDVA difference ＞20/70 in the unilateral group. Postoperative CDVA ≤20/100 and preservation of posterior capsule, and presence of secondary cataract were significant factors in both groups.CONCLUSION: Children with congenital cataracts should be monitored carefully after cataract surgery for the development of strabismus, especially when they underwent surgery at age ≤1y, and they have nystagmus, large postoperative interocular CDVA difference, poor preoperative and postoperative CDVA, preservation of the posterior capsule, or secondary cataract.

Mouse nucleolin binds to 4.5S RNAH, a small noncoding RNA

International Nuclear Information System (INIS)

Hirose, Yutaka; Harada, Fumio

2008-01-01

4.5S RNAH is a rodent-specific small noncoding RNA that exhibits extensive homology to the B1 short interspersed element. Although 4.5S RNAH is known to associate with cellular poly(A)-terminated RNAs and retroviral genomic RNAs, its function remains unclear. In this study, we analyzed 4.5S RNAH-binding proteins in mouse nuclear extracts using gel mobility shift and RNA-protein UV cross-linking assays. We found that at least nine distinct polypeptides (p170, p110, p93, p70, p48, p40, p34, p20, and p16.5) specifically interacted with 4.5S RNAHin vitro. Using anti-La antibody, p48 was identified as mouse La protein. To identify the other 4.5S RNAH-binding proteins, we performed expression cloning from a mouse cDNA library and obtained cDNA clones derived from nucleolin mRNA. We identified p110 as nucleolin using nucleolin-specific antibodies. UV cross-linking analysis using various deletion mutants of nucleolin indicated that the third of four tandem RNA recognition motifs is a major determinant for 4.5S RNAH recognition. Immunoprecipitation of nucleolin from the subcellular fractions of mouse cell extracts revealed that a portion of the endogenous 4.5S RNAH was associated with nucleolin and that this complex was located in both the nucleoplasm and nucleolus

Signature inversion of the semi-decoupled band in the odd-odd nucleus 170Ta

International Nuclear Information System (INIS)

Deng Fuguo; Yang Chunxiang; Zhou Hongyu; Sun Huibin; Lu Jingbin; Zhao Guangyi; Yin Lichang; Liu Yunzuo

2001-01-01

The high-spin states of the odd-odd nucleus 170 Ta have been studied by the 155 Gd( 19 F, 4n) 170 Ta reaction at the beam energy of 97 MeV. The α = 1 sequence of the semi-decoupled band has been pushed to higher-spin states and the signature inversion point was observed at 19.5 ℎ. the results are compared with those of the neighbouring odd-odd nuclei

Steam producing plant concept of 4S for oil sand extraction

International Nuclear Information System (INIS)

Matsuyama, Shinichiro; Nishiguchi, Youhei; Sakashita, Yoshiaki; Kasuga, Shoji; Kawashima, Masatoshi

2009-01-01

Plant concept of small fast reactor '4S' applying to continuous steam production for recovery of crude oil from oil sands was investigated. Assuming typical steam assisted gravity drainage (SAGD) plant whose production scale is 120,000 barrels per day of a crude oil, concept of nuclear steam supply system consisting of eight reactor modules for steam production and three reactor modules for electric generation of the 4S with a thermal rating of 135 MWt was established without any essential or significant design change from the preceding 4S with a thermal rating of 30 MWt. The 4S, provided for an oil sand extraction, will reduce greenhouse gas emission significantly, and has not much burden for development and licensing and has economic competitiveness. (author)

Comparative assay of glutathione S-transferase (GSTs) activity of excretory-secretory materials and somatic extract of Fasciola spp parasites.

Science.gov (United States)

Alirahmi, Heshmatollah; Farahnak, Ali; Golmohamadi, Taghi; Esharghian, Mohammad Reza

2010-01-01

Fascioliasis is a worldwide parasitic disease in human and domestic animals. The causative agents of fascioliasis are Fasciola hepatica and Fasciola gigantica. In the recent years, fasciola resistance to drugs has been reported in the many of publications. Fasciola spp has detoxification system including GST enzyme which may be responsible for its resistance. Therefore , the aim of the study was to assay of GST enzyme activity in fasciola parasites. Fasciola gigantica and Fasciola hepatica helminths were collected from abattoir as a live and cultured in buffer media for 4 h at 37 °C. Excretory-Secretory products were collected and stored in -80◦C. F. gigantica and Fasciola hepatica were homogenized with homogenizing buffer in a glass homogenizer to prepare of somatic extract. Suspension was then centrifuged and supernatant was stored at -80°C. In order to assay the enzyme activity, excretory-secretory and somatic extracts in the form of cocktails (potassium phosphate buffer, reduced glutathione and 1-chloro-2,4-dinitrobenzene substrates) were prepared and their absorbance recorded for 5 minutes at 340 nm. The total and specific GST activity of F. gigantica somatic and ES products were obtained as 2916.00, 272.01 micromole/minute and 1.33, 1.70 micromole/minute/mg protein, respectively. Fasciola hepatica also showed 2705.00, 276.86 micromole/minute and 1.33, 1.52 micromole/minute/mg protein, respectively. These results are important for analysis of parasite survival / resistance to drugs which use for treatment of fascioliasis.

The effect of Tea Misletoe (Scurrula oortiana Stem Extract as Immuno-Modulator on Oncogenic Marek’s Disease Virus Infection

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Mulyoto Samsi

2007-11-01

Full Text Available Marek’s disease virus (MDV is one of oncogenic herpesvirus. It causes immunosupresion and cancer in chicken. Several plants produce bioactive compounds which are very useful for treatment of many disease, especially hiperproliveration and virus infection. This study was aimed to find out mechanism of immuno-modulatory capacity in layer commercial chicken administered orally with extract of tea parasite (Scurrula oortiana in dose of 10 mg/kg BW through drinking water, then the chicken were infected by intraperitoneal oncogenic MDV in dose of 1,0 x103 TCID50. The study used 60 layer commercial day old chicks (DOC divided into four group treatments. The treatments were group A (administered S. oortiana extract and without MDV infection, B (neither S. oortiana nor MDV infection, C (administered S. oortiana extract and with MDV infection, and D (without administered S. oortiana extract, but with MDV infection. Results showed that MDV oncogenic caused immunosupresion at a day post infection (p.i and recovery to be normal based on relative weight of bursa Fabricius and thymus at 40 days p.i. The extract of S. oortiana had a capability as an immunomodulator indicated by the increase of relative weight of bursa Fabricius and thymus at day 20 days p.i. (Animal Production 9(2: 172-177 (2007 Key Words: Marek’s disease virus (MDV, Scurrula oortiana, immuno-modulator

Removal of H2S and volatile organic sulfur compounds by silicone membrane extraction

NARCIS (Netherlands)

Manconi, I.; Lens, P.N.L.

2009-01-01

BACKGROUND: This study explores an alternative process for the abatement and/or desulfurization of H2S and volatile organic sulfur compounds (VOSC) containing waste streams, which employs a silicone-based membrane to simultaneously remove H2S and VOSC. An extractive membrane reactor allows the

Training by visual identification and writing leads to different visual word expertise N170 effects in preliterate Chinese children

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Pei Zhao

2015-10-01

Full Text Available The N170 component of EEG evoked by visual words is an index of perceptual expertise for the visual word across different writing systems. In the present study, we investigated whether these N170 markers for Chinese, a very complex script, could emerge quickly after short-term learning (∼100 min in young Chinese children, and whether early writing experience can enhance the acquisition of these neural markers for expertise. Two groups of preschool children received visual identification and free writing training respectively. Short-term character training resulted in selective enhancement of the N170 to characters, consistent with normal expert processing. Visual identification training resulted in increased N170 amplitude to characters in the right hemisphere, and N170 amplitude differences between characters and faces were decreased; whereas the amplitude difference between characters and tools increased. Writing training led to the disappearance of an initial amplitude difference between characters and faces in the right hemisphere. These results show that N170 markers for visual expertise emerge rapidly in young children after word learning, independent of the type of script young children learn; and visual identification and writing produce different effects.

Transforming growth factor beta 1 expression and inflammatory cells in tooth extraction socket after X-ray irradiation

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Ramadhan Hardani Putra

2016-06-01

Full Text Available Background: Radiographic examination is often used in dentistry to evaluate tooth extraction complications. X-ray used in radiographic examination, however, has negative effects, including damage to DNA and inflammatory response during wound healing process. Purpose: This study aimed to analyze the effects of X-ray irradiation on transforming growth factor beta 1 (TGF-ß1 expression and number of inflammatory cells in tooth extraction sockets. Method: Thirty rats were divided into three groups, which consist of control group (with a radiation of 0 mSv, treatment group 1 (with a radiation of 0.08 mSv, and treatment group 2 (with a radiation of 0.16 mSv. These rats in each group were sacrificed on days 3 and 5 after treatment. Inflammatory cells which were observed in this research were PMN, macrophages, and lymphocytes. Histopathological and immunohistochemical examinations were used to calculate the number of inflammatory cells and TGF-ß1 expression. Obtained data were analyzed using SPSS 16.0 software with one way ANOVA and Tukey’s HSD tests. Result: There was no significant decrease in the number of PMN. On the other hand, there were significant decreases in the number of macrophages and lymphocytes in the sacrificed group on day-5 with the radiation of 0.16 mSv. Similarly, the most significant decreased expression of TGF-ß1 was found in the group sacrificed on day 5 with the radiation of 0.16 mSv. Conclusion: X-ray irradiation with 0.08 mSv and 0.16 mSv doses can decrease TGF-ß1 expression and number of inflammatory cells in tooth extraction sockets on day 3 and 5 post extraction.

25 CFR 170.412 - How is the tribal IRR long-range transportation plan developed and approved?

Science.gov (United States)

2010-04-01

...-range transportation plan developed and approved? (a) The tribal IRR long-range transportation plan is... 25 Indians 1 2010-04-01 2010-04-01 false How is the tribal IRR long-range transportation plan developed and approved? 170.412 Section 170.412 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR...

Sample clean-up, enrichment and determination of s-triazine herbicides from southern ethiopian lakes supported using liquid membrane extraction

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Jan Åke Jönsson

2000-06-01

Full Text Available The liquid membrane extraction method has been employed for selectively extracting trace quantities of s-triazine herbicides in environmental waters collected from lakes Awassa, Chamo and Abbya, located in close proximity to the agricultural farms in Southern Ethiopia. In liquid membrane extraction, the uncharged triazine compounds from the flowing donor solution diffuse through a porous poly(tetrafluoroethylene (PTFE membrane, containing a water immiscible organic solvent. The s-triazine molecules are then irreversibly trapped in the stagnant acidic acceptor phase since they become protonated. Using both di-n-hexylether and n-undecane membrane solvents, s-traizine herbicides were extracted and low detection limits of about 1 ng/L have been obtained by extraction of three liters of sample solution spiked with 0.1 g/L of each triazine. Residues of atrazine and terbutryn ranging in concentration from 0.02 to 0.05 g/L have been successfully determined.

48 CFR 1602.170-5 - Cost or pricing data.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Cost or pricing data. 1602... Terms 1602.170-5 Cost or pricing data. (a) Experience-rated carriers. Cost or pricing data for... pricing data for community rated carriers is the specialized rating data used by carriers in computing a...

Extracting CKM phases from angular distributions of $B_{d,s}$ decays into admixtures of CP eigenstates

CERN Document Server

Fleischer, Robert

1999-01-01

The time-dependent angular distributions of certain B/sub d, s/ decays into final states that are admixtures of CP-even and CP-odd configurations provide valuable information about CKM phases and hadronic parameters. We present the general formalism to accomplish this task, taking also into account penguin contributions, and illustrate it by considering a few specific decay modes. We give particular emphasis to the decay B/sub d/ to J/ psi rho /sup 0/, which can be combined with B/sub s/ to J/ psi phi to extract the B /sub d//sup 0/-B/sub d//sup 0/ mixing phase and-if penguin effects in the former mode should be sizeable-also the angle gamma of the unitarity triangle. As an interesting by-product, this strategy allows us to take into account also the penguin effects in the extraction of the B/sub s//sup 0/-B/sub s//sup 0/ mixing phase from B /sub s/ to J/ psi phi . Moreover, a discrete ambiguity in the extraction of the CKM angle beta can be resolved, and valuable insights into SU(3)-breaking effects can be o...

A Discrete-Time Algorithm for Stiffness Extraction from sEMG and Its Application in Antidisturbance Teleoperation

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Peidong Liang

2016-01-01

Full Text Available We have developed a new discrete-time algorithm of stiffness extraction from muscle surface electromyography (sEMG collected from human operator’s arms and have applied it for antidisturbance control in robot teleoperation. The variation of arm stiffness is estimated from sEMG signals and transferred to a telerobot under variable impedance control to imitate human motor control behaviours, particularly for disturbance attenuation. In comparison to the estimation of stiffness from sEMG, the proposed algorithm is able to reduce the nonlinear residual error effect and to enhance robustness and to simplify stiffness calibration. In order to extract a smoothing stiffness enveloping from sEMG signals, two enveloping methods are employed in this paper, namely, fast linear enveloping based on low pass filtering and moving average and amplitude monocomponent and frequency modulating (AM-FM method. Both methods have been incorporated into the proposed stiffness variance estimation algorithm and are extensively tested. The test results show that stiffness variation extraction based on the two methods is sensitive and robust to attenuation disturbance. It could potentially be applied for teleoperation in the presence of hazardous surroundings or human robot physical cooperation scenarios.

Simultaneous micro-electromembrane extractions of anions and cations using multiple free liquid membranes and acceptor solutions

Czech Academy of Sciences Publication Activity Database

Kubáň, Pavel; Boček, Petr

2016-01-01

Roč. 908, FEB (2016), s. 113-120 ISSN 0003-2670 R&D Projects: GA ČR(CZ) GA13-05762S Institutional support: RVO:68081715 Keywords : free liquid membranes * micro-electromembrane extraction * simultaneous extractions Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 4.950, year: 2016

Simultaneous micro-electromembrane extractions of anions and cations using multiple free liquid membranes and acceptor solutions

Czech Academy of Sciences Publication Activity Database

Kubáň, Pavel; Boček, Petr

2016-01-01

Roč. 908, FEB (2016), s. 113-120 ISSN 0003-2670 R&D Projects: GA ČR(CZ) GA13-05762S Institutional support: RVO:68081715 Keywords : free liquid membranes * micro-electromembrane extraction * simultaneous extractions Subject RIV: CB - Analytical Chemistry , Separation Impact factor: 4.950, year: 2016

Optimal Elbow Angle for Extracting sEMG Signals During Fatiguing Dynamic Contraction

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Mohamed R. Al-Mulla

2015-09-01

Full Text Available Surface electromyographic (sEMG activity of the biceps muscle was recorded from 13 subjects. Data was recorded while subjects performed dynamic contraction until fatigue and the signals were segmented into two parts (Non-Fatigue and Fatigue. An evolutionary algorithm was used to determine the elbow angles that best separate (using Davies-Bouldin Index, DBI both Non-Fatigue and Fatigue segments of the sEMG signal. Establishing the optimal elbow angle for feature extraction used in the evolutionary process was based on 70% of the conducted sEMG trials. After completing 26 independent evolution runs, the best run containing the optimal elbow angles for separation (Non-Fatigue and Fatigue was selected and then tested on the remaining 30% of the data to measure the classification performance. Testing the performance of the optimal angle was undertaken on nine features extracted from each of the two classes (Non-Fatigue and Fatigue to quantify the performance. Results showed that the optimal elbow angles can be used for fatigue classification, showing 87.90% highest correct classification for one of the features and on average of all eight features (including worst performing features giving 78.45%.

Time Domain Feature Extraction Technique for earth's electric field signal prior to the Earthquake

International Nuclear Information System (INIS)

Astuti, W; Sediono, W; Akmeliawati, R; Salami, M J E

2013-01-01

Earthquake is one of the most destructive of natural disasters that killed many people and destroyed a lot of properties. By considering these catastrophic effects, it is highly important of knowing ahead of earthquakes in order to reduce the number of victims and material losses. Earth's electric field is one of the features that can be used to predict earthquakes (EQs), since it has significant changes in the amplitude of the signal prior to the earthquake. This paper presents a detailed analysis of the earth's electric field due to earthquakes which occurred in Greece, between January 1, 2008 and June 30, 2008. In that period of time, 13 earthquakes had occurred. 6 of them were recorded with magnitudes greater than Ms=5R (5R), while 7 of them were recorded with magnitudes greater than Ms=6R (6R). Time domain feature extraction technique is applied to analyze the 1st significant changes in the earth's electric field prior to the earthquake. Two different time domain feature extraction techniques are applied in this work, namely Simple Square Integral (SSI) and Root Mean Square (RMS). The 1st significant change of the earth's electric field signal in each of monitoring sites is extracted using those two techniques. The feature extraction result can be used as input parameter for an earthquake prediction system

In-vitro effect of flavonoids from Solidago canadensis extract on glutathione S-transferase.

Science.gov (United States)

Apáti, Pál; Houghton, Peter J; Kite, Geoffrey; Steventon, Glyn B; Kéry, Agnes

2006-02-01

Solidago canadensis is typical of a flavonoid-rich herb and the effect of an aqueous ethanol extract on glutathione-S-transferase (GST) activity using HepG2 cells was compared with those of the flavonol quercetin and its glycosides quercitrin and rutin, found as major constituents. The composition of the extract was determined by HPLC and rutin was found to be the major flavonoidal component of the extract. Total GST activity was assessed using 1-chloro-2,4-dinitrobenzene as a substrate. The glycosides rutin and quercitrin gave dose-dependent increases in GST activity, with a 50% and 24.5% increase at 250 mM, respectively, while the aglycone quercetin inhibited the enzyme by 30% at 250 mM. The total extract of the herb gave an overall dose-dependent increase, the fractions corresponding to the flavonoids showed activating effects while those containing caffeic acid derivatives were inhibitory. The activity observed corresponds to that reported for similar compounds in-vivo using rats, thus the HepG2 cell line could serve as a more satisfactory method of assessing the effects of extracts and compounds on GST.

Effect of Withania somnifera leaf extract on the dietary supplementation in transgenic Drosophila model of Parkinson’s disease

Directory of Open Access Journals (Sweden)

YASIR HASAN SIDDIQUE

2015-09-01

Full Text Available The role of Withania somnifera L. leaf extract was studied on the transgenic Drosophila model flies expressing normal human alpha synuclein (h-αS in the neurons. The leaf extract was prepared in acetone and was subjected to GC-MS analysis. W. somnifera extract at final concentration of 0.25, 0.50 and 1.0 µL/mL was mixed with the diet and the flies were allowed to feed for 24 days. The effect of extract was studied on the climbing ability, lipid peroxidation and protein carbonyl content in the brains of transgenic Drosophila. The exposure of extract to PD model flies did not show any significant delay in the loss of climbing ability nor reduced the oxidative stress in the brains of transgenic Drosophila as compared to untreated PD model flies. The results suggest that W. somnifera leaf extract is not potent in reducing the PD symptoms in transgenic Drosophila model of Parkinson’s disease.

Super/Subcritical Fluid Extractions for Preparation of the Crystalline Titania

Czech Academy of Sciences Publication Activity Database

Matějová, Lenka; Cajthaml, Tomáš; Matěj, Z.; Benada, Oldřich; Klusoň, Petr; Šolcová, Olga

2010-01-01

Roč. 52, č. 2 (2010), s. 215-221 ISSN 0896-8446 R&D Projects: GA ČR GP104/09/P290; GA ČR GA104/09/0694 Institutional research plan: CEZ:AV0Z40720504; CEZ:AV0Z50200510 Keywords : titania * supercritical fluid extraction * pressurised fluid extraction Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 2.986, year: 2010

Radioimmunoassay of extracted glucagon compared with three non-extraction assays

International Nuclear Information System (INIS)

Schenck, H. von; Nilsson, O.R.

1981-01-01

Radioimmunoassay of glucagon was performed with three different antisera, i.e. E7, 30K and 4305, all directed against the carboxyl-terminal region of glucagon and thus avoiding co-determination of glucagon-like polypeptides from the gut. Plasma samples from five healthy people subjected to various A-cell stimulation and suppression tests were used and immunoreactive glucagon assessed with the three antisera. Aliquots from all plasma samples were also extracted with acetone and glucagon re-assessed with antiserum E7. Even though all four baseline glucagon concentrations obtained were different, the glucagon profiles were comparable after superimposing the baselines. The differences in baseline concentrations of immunoreactive glucagon seem due to the interference of 'big plasma glucagon', a still unidentified factor in the E7 and 30K assays that can be precipitated by acetone. Since acetone extraction yielded the lowest baselines without altering the glucagon profiles, it is suggsted that the baseline glucagon concentrations of acetone-extracted plasma reflect the physiological level of the biologically active hormone. Using antiserum E7, our own antiserum, the normal range of glucagon values in acetone-extracted plasma samples from 22 healthy, fasting people of both sexes was 42+-16 ng/l (mean +- 2 S.D.). These values agree well with those obtained by other assay techniques. (Auth.)

Towards a 1 MW, 170 GHz gyrotron design for fusion application

Science.gov (United States)

Kumar, Anil; Kumar, Nitin; Singh, Udaybir; Bhattacharya, Ranajoy; Yadav, Vivek; Sinha, A. K.

2013-03-01

The electrical design of different components of 1 MW, 170 GHz gyrotron such as, magnetron injection gun, cylindrical interaction cavity and collector and RF window is presented in this article. Recently, a new project related to the development of 170 GHz, 1 MW gyrotron has been started for the Indian Tokamak. TE34,10 mode is selected as the operating mode after studied the problem of mode competition. The triode type geometry is selected for the design of magnetron injection gun (MIG) to achieve the required beam parameters. The maximum transverse velocity spread of 3.28% at the velocity ratio of 1.34 is obtained in simulations for a 40 A, 80 kV electron beam. The RF output power of more than 1 MW with 36.5% interaction efficiency without depressed collector is predicted by simulation in single-mode operation at 170 GHz frequency. The simulated single-stage depressed collector of the gyrotron predicted the overall device efficiencies >55%. Due to the very good thermal conductivity and very weak dependency of the dielectric parameters on temperature, PACVD diamond is selected for window design for the transmission of RF power. The in-house developed code MIGSYN and GCOMS are used for initial geometry design of MIG and mode selection respectively. Commercially available simulation tools MAGIC and ANSYS are used for beam-wave interaction and mechanical analysis respectively.

Search for Unstable Heavy and Excited Leptons in $e^+ e^-$ Collisions at $\\sqrt{s}$ = 170-172 GeV

CERN Document Server

Ackerstaff, K; Allison, J; Altekamp, N; Anderson, K J; Anderson, S; Arcelli, S; Asai, S; Axen, D A; Azuelos, Georges; Ball, A H; Barberio, E; Barlow, R J; Bartoldus, R; Batley, J Richard; Baumann, S; Bechtluft, J; Beeston, C; Behnke, T; Bell, A N; Bell, K W; Bella, G; Bentvelsen, Stanislaus Cornelius Maria; Bethke, Siegfried; Biebel, O; Biguzzi, A; Bird, S D; Blobel, Volker; Bloodworth, Ian J; Bloomer, J E; Bobinski, M; Bock, P; Bonacorsi, D; Boutemeur, M; Bouwens, B T; Braibant, S; Brigliadori, L; Brown, R M; Burckhart, Helfried J; Burgard, C; Bürgin, R; Capiluppi, P; Carnegie, R K; Carter, A A; Carter, J R; Chang, C Y; Charlton, D G; Chrisman, D; Clarke, P E L; Cohen, I; Conboy, J E; Cooke, O C; Cuffiani, M; Dado, S; Dallapiccola, C; Dallavalle, G M; Davis, R; De Jong, S; del Pozo, L A; Desch, Klaus; Dienes, B; Dixit, M S; do Couto e Silva, E; Doucet, M; Duchovni, E; Duckeck, G; Duerdoth, I P; Eatough, D; Edwards, J E G; Estabrooks, P G; Evans, H G; Evans, M; Fabbri, Franco Luigi; Fanti, M; Faust, A A; Fiedler, F; Fierro, M; Fischer, H M; Fleck, I; Folman, R; Fong, D G; Foucher, M; Fürtjes, A; Futyan, D I; Gagnon, P; Gary, J W; Gascon, J; Gascon-Shotkin, S M; Geddes, N I; Geich-Gimbel, C; Geralis, T; Giacomelli, G; Giacomelli, P; Giacomelli, R; Gibson, V; Gibson, W R; Gingrich, D M; Glenzinski, D A; Goldberg, J; Goodrick, M J; Gorn, W; Grandi, C; Gross, E; Grunhaus, Jacob; Gruwé, M; Hajdu, C; Hanson, G G; Hansroul, M; Hapke, M; Hargrove, C K; Hart, P A; Hartmann, C; Hauschild, M; Hawkes, C M; Hawkings, R; Hemingway, Richard J; Herndon, M; Herten, G; Heuer, R D; Hildreth, M D; Hill, J C; Hillier, S J; Hobson, P R; Homer, R James; Honma, A K; Horváth, D; Hossain, K R; Howard, R; Hüntemeyer, P; Hutchcroft, D E; Igo-Kemenes, P; Imrie, D C; Ingram, M R; Ishii, K; Jawahery, A; Jeffreys, P W; Jeremie, H; Jimack, Martin Paul; Joly, A; Jones, C R; Jones, G; Jones, M; Jost, U; Jovanovic, P; Junk, T R; Karlen, D A; Kartvelishvili, V G; Kawagoe, K; Kawamoto, T; Kayal, P I; Keeler, Richard K; Kellogg, R G; Kennedy, B W; Kirk, J; Klier, A; Kluth, S; Kobayashi, T; Kobel, M; Koetke, D S; Kokott, T P; Kolrep, M; Komamiya, S; Kress, T; Krieger, P; Von Krogh, J; Kyberd, P; Lafferty, G D; Lahmann, R; Lai, W P; Lanske, D; Lauber, J; Lautenschlager, S R; Layter, J G; Lazic, D; Lee, A M; Lefebvre, E; Lellouch, Daniel; Letts, J; Levinson, L; Lloyd, S L; Loebinger, F K; Long, G D; Losty, Michael J; Ludwig, J; Macchiolo, A; MacPherson, A L; Mannelli, M; Marcellini, S; Markus, C; Martin, A J; Martin, J P; Martínez, G; Mashimo, T; Mättig, P; McDonald, W J; McKenna, J A; McKigney, E A; McMahon, T J; McPherson, R A; Meijers, F; Menke, S; Merritt, F S; Mes, H; Meyer, J; Michelini, Aldo; Mikenberg, G; Miller, D J; Mincer, A; Mir, R; Mohr, W; Montanari, A; Mori, T; Morii, M; Müller, U; Mihara, S; Nagai, K; Nakamura, I; Neal, H A; Nellen, B; Nisius, R; O'Neale, S W; Oakham, F G; Odorici, F; Ögren, H O; Oh, A; Oldershaw, N J; Oreglia, M J; Orito, S; Pálinkás, J; Pásztor, G; Pater, J R; Patrick, G N; Patt, J; Pearce, M J; Pérez-Ochoa, R; Petzold, S; Pfeifenschneider, P; Pilcher, J E; Pinfold, J L; Plane, D E; Poffenberger, P R; Poli, B; Posthaus, A; Rees, D L; Rigby, D; Robertson, S; Robins, S A; Rodning, N L; Roney, J M; Rooke, A M; Ros, E; Rossi, A M; Routenburg, P; Rozen, Y; Runge, K; Runólfsson, O; Ruppel, U; Rust, D R; Rylko, R; Sachs, K; Saeki, T; Sarkisyan-Grinbaum, E; Sbarra, C; Schaile, A D; Schaile, O; Scharf, F; Scharff-Hansen, P; Schenk, P; Schieck, J; Schleper, P; Schmitt, B; Schmitt, S; Schöning, A; Schröder, M; Schultz-Coulon, H C; Schumacher, M; Schwick, C; Scott, W G; Shears, T G; Shen, B C; Shepherd-Themistocleous, C H; Sherwood, P; Siroli, G P; Sittler, A; Skillman, A; Skuja, A; Smith, A M; Snow, G A; Sobie, Randall J; Söldner-Rembold, S; Springer, R W; Sproston, M; Stephens, K; Steuerer, J; Stockhausen, B; Stoll, K; Strom, D; Szymanski, P; Tafirout, R; Talbot, S D; Tanaka, S; Taras, P; Tarem, S; Teuscher, R; Thiergen, M; Thomson, M A; Von Törne, E; Towers, S; Trigger, I; Trócsányi, Z L; Tsur, E; Turcot, A S; Turner-Watson, M F; Utzat, P; Van Kooten, R; Verzocchi, M; Vikas, P; Vokurka, E H; Voss, H; Wäckerle, F; Wagner, A; Ward, C P; Ward, D R; Watkins, P M; Watson, A T; Watson, N K; Wells, P S; Wermes, N; White, J S; Wilkens, B; Wilson, G W; Wilson, J A; Wolf, G; Wyatt, T R; Yamashita, S; Yekutieli, G; Zacek, V; Zer-Zion, D

1998-01-01

We have searched for unstable neutral and charged heavy leptons, N and L^+/-, and for excited states of neutral and charged leptons, nu*, e*, mu* and tau*, in e^+e^- collisions at centre-of-mass energies of 170 and 172 GeV using the OPAL detector at LEP. No evidence for their existence was found. From the analysis of charged-current decays of pair-produced unstable heavy leptons, and of charged-current and photonic decays of pair-produced excited leptons, lower limits on their masses are derived. From the analysis of charged-current and photonic decays of singly-produced excited leptons, upper limits on the ratio of the coupling to the compositeness scale, f/Lambda, are determined for masses up to the kinematic limit.

Efficient charge-carrier extraction from Ag₂S quantum dots prepared by the SILAR method for utilization of multiple exciton generation.

Science.gov (United States)

Zhang, Xiaoliang; Liu, Jianhua; Johansson, Erik M J

2015-01-28

The utilization of electron-hole pairs (EHPs) generated from multiple excitons in quantum dots (QDs) is of great interest toward efficient photovoltaic devices and other optoelectronic devices; however, extraction of charge carriers remains difficult. Herein, we extract photocharges from Ag2S QDs and investigate the dependence of the electric field on the extraction of charges from multiple exciton generation (MEG). Low toxic Ag2S QDs are directly grown on TiO2 mesoporous substrates by employing the successive ionic layer adsorption and reaction (SILAR) method. The contact between QDs is important for the initial charge separation after MEG and for the carrier transport, and the space between neighbor QDs decreases with more SILAR cycles, resulting in better charge extraction. At the optimal electric field for extraction of photocharges, the results suggest that the threshold energy (hνth) for MEG is 2.41Eg. The results reveal that Ag2S QD is a promising material for efficient extraction of charges from MEG and that QDs prepared by SILAR have an advantageous electrical contact facilitating charge separation and extraction.

Electromembrane extraction using stabilized constant d.c. electric current — A simple tool for improvement of extraction performance

Czech Academy of Sciences Publication Activity Database

Šlampová, Andrea; Kubáň, Pavel; Boček, Petr

2012-01-01

Roč. 1234, APR 20 (2012), s. 32-37 ISSN 0021-9673 R&D Projects: GA ČR GAP206/10/1219 Institutional research plan: CEZ:AV0Z40310501 Keywords : electromembrane extraction * sample pretreatment * supported liquid membranes Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 4.612, year: 2012

Synthesis of [11C]PBR170, a novel imidazopyridine, for imaging the translocator protein with PET

International Nuclear Information System (INIS)

Bourdier, Thomas; Henderson, David; Fookes, Christopher J.R.; Lam, Peter; Mattner, Filomena; Fulham, Michael; Katsifis, Andrew

2014-01-01

The translocator protein (TSPO) ligand 2-(6,8-dichloro-2-(4-ethoxyphenyl)imidazo[1,2-a]pyridin-3-yl) –N-(2-fluoropyridin-3-yl)–N-methylacetamide (PBR170), is a novel imidazopyridineacetamide with high affinity (2.6 nm) and selectivity for the TSPO. The synthesis of [ 11 C]PBR170 was accomplished by N-methylation of the corresponding desmethyl precursor with [ 11 C]methyl iodide in the presence of sodium hydroxide in dimethylformamide. [ 11 C]PBR170 was produced in 30–45% radiochemical yield (decay-corrected, based on [ 11 C]methyl iodide) with a radiochemical purity >98% and a specific activity of 90–190 GBq/μmol after 35 min of synthesis time. - Highlights: • Radiosynthesis of a novel ligand PBR170 with carbon-11. • 30–45% radiochemical yield (decay-corrected, based on [ 11 C]methyl iodide). • Radiosynthesis and formulation achieved in 35 min. • High radiochemical purity (>98%) and specific activity (90–190 GBq/µmol). • High affinity and selectivity for the translocator protein (TSPO)

Safety of Malaysian marine endophytic fungal extract S2 from a brown seaweed Turbinaria conoides

Directory of Open Access Journals (Sweden)

Siti Alwani Ariffin

2014-07-01

Full Text Available Objective: To evaluate the in vivo acute toxicity and antioxidant activity of the marine endophytic fungus extract S2 isolated from Turbinaria conoides. Methods: Two doses (100 mg/kg and 400 mg/kg of the S2 extract were administered to rats orally for acute toxicity and antioxidant test. The body weight, relative weight of six organs, haematological, biochemical and antioxidant properties were investigated on Day 14. Results: A single oral dose treatment did not cause any mortality or observable adverse effects in rats. No significant variations in the body and organ weights between the control and the treated groups were observed. Heamatological analysis and clinical blood chemistry also did not reveal any toxic effects of the extract. The total white blood cell count and haemoglobin levels were increased. The levels of total serum cholesterol in males treated with 100 and 400 mg/kg were significantly (P<0.05 decreased (1.28 and 1.34 mmol/L respectively compared to control (1.55 mmol/L rats. Pathologically, neither gross abnormalities nor histopathological changes were observed. This study showed strong evidence of the non-toxic effects of S2 extract. Furthermore the extract exhibited significant (P<0.05 antioxidant activity through increased levels of superoxide dismutase and glutathione peroxidase enzymes in serum, liver and kidney. Conclusions: The research findings from the present study showed the potential of marine natural products particularly in Malaysia as a source of bioactive compounds. Marine endophytic fungi as a potential source of anticancer drugs with great potential as they are potent yet safe, thus deserving further extensive investigation.

The N170 component is sensitive to face-like stimuli: a study of Chinese Peking opera makeup.

Science.gov (United States)

Liu, Tiantian; Mu, Shoukuan; He, Huamin; Zhang, Lingcong; Fan, Cong; Ren, Jie; Zhang, Mingming; He, Weiqi; Luo, Wenbo

2016-12-01

The N170 component is considered a neural marker of face-sensitive processing. In the present study, the face-sensitive N170 component of event-related potentials (ERPs) was investigated with a modified oddball paradigm using a natural face (the standard stimulus), human- and animal-like makeup stimuli, scrambled control images that mixed human- and animal-like makeup pieces, and a grey control image. Nineteen participants were instructed to respond within 1000 ms by pressing the ' F ' or ' J ' key in response to the standard or deviant stimuli, respectively. We simultaneously recorded ERPs, response accuracy, and reaction times. The behavioral results showed that the main effect of stimulus type was significant for reaction time, whereas there were no significant differences in response accuracies among stimulus types. In relation to the ERPs, N170 amplitudes elicited by human-like makeup stimuli, animal-like makeup stimuli, scrambled control images, and a grey control image progressively decreased. A right hemisphere advantage was observed in the N170 amplitudes for human-like makeup stimuli, animal-like makeup stimuli, and scrambled control images but not for grey control image. These results indicate that the N170 component is sensitive to face-like stimuli and reflect configural processing in face recognition.

The impact of plasma rich in growth factors on clinical and biological factors involved in healing processes after third molar extraction.

Science.gov (United States)

Mozzati, Marco; Martinasso, Germana; Pol, Renato; Polastri, Carolina; Cristiano, Antonio; Muzio, Giuliana; Canuto, Rosa

2010-12-01

Extraction of an impacted mandibular third molar is a common surgical procedure, although it still leads to several postoperative symptoms and complications. The study assessed the efficacy of autologous plasma rich in growth factors (PRGF) in the healing process by checking the difference of tissue cytokines and other healing factors produced by the mucosa after extraction between sites treated with PRGF and control sites and, at the same time, by evaluating the clinical efficacy of PRGF in terms of reduced pain and facial swelling. This study was a split-mouth study, in which the patient becomes his/her own control, to eliminate any individual response differences toward PRGF treatment. The parameters regarding inflammation and subsequent wound healing were all significantly higher at PRGF sites than at control sites. The increase at PRGF sites of the two proinflammatory cytokines evaluated, interleukin (IL)-1β and IL-6, was accompanied by the increase of two anti-inflammatory cytokines, IL-10 and transforming growth factor-β. Furthermore, IL-1β and IL-6 induce fibroblast and keratinocyte proliferation, important events in wound healing. Postoperative pain and the swelling, measured at all experimental times, were reduced in the presence of PRGF. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2010.

Influence of Extraction Parameters on Hydroalcohol Extracts of the ...

African Journals Online (AJOL)

The parameter that had the greatest influence on extraction process was alcohol concentration ... rules and processing steps [2]. As part .... Table 1: Extractive batch nnumbers with the respective factors and levels studied in the factorial design.

Solid-phase extraction of berries’ anthocyanins and evaluation of their antioxidative properties

Czech Academy of Sciences Publication Activity Database

Denev, P.; Číž, Milan; Ambrožová, Gabriela; Lojek, Antonín; Yanakieva, I.; Kratchanova, M.

2010-01-01

Roč. 123, č. 4 (2010), s. 1055-1061 ISSN 0308-8146 R&D Projects: GA MŠk(CZ) OC08058 Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702 Keywords : anthocyanins * solid-phase extraction * berry extracts Subject RIV: BO - Biophysics Impact factor: 3.458, year: 2010

21 CFR 111.170 - What requirements apply to rejected components, packaging, and labels, and to rejected products...

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What requirements apply to rejected components... supplement? 111.170 Section 111.170 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION CURRENT GOOD MANUFACTURING PRACTICE IN...

25 CFR 170.622 - What IRR programs, functions, services, and activities are subject to the self-governance...

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false What IRR programs, functions, services, and activities are subject to the self-governance construction regulations? 170.622 Section 170.622 Indians BUREAU OF..., functions, services, and activities are subject to the self-governance construction regulations? All IRR...

The Effect of Hydroalcoholic Extract of Nectaroscordum Tripedale on Biochemical Factors in Diabetic Rats

Directory of Open Access Journals (Sweden)

S Paydar

2015-08-01

Full Text Available Background & aim: The therapeutic effects of traditional medicinal plants used in traditional medicine for many diseases have been proved. The present study was undertaken to investigate the effect of oral administration of different doses of hydroalcoholic extract of Nectaroscordum tripedale on biochemical factors. Method: Forty adult male Sprague Dawley rats were randomly divided into five groups of 8 animals as follows control group (recieved distilled water, control +50 mg/kg Nectaroscordum tripedale, diabetic control group (recieved distilled water, treatment group 1 (recieved 50mg/kg Nectaroscordum tripedale, treatment group 2 (recieved 100 mg/kg Nectaroscordum tripedales. The animals recieved Nectaroscordum tripedales extract by gavage for 21 days. Diabetes was induced by a single injection streptozotocin in rat (50 mg/kg b.w., ip. Before and 3 days after injection, 7, 14 and 21 days of treatment, the fasting glucose level and weight was measured. At the end of 21 days, blood samples collected from the heart puncture, after animals anesthetized with ether. The blood samples were analysed for lipid profile (total cholesterol, TG, HDL-c, LDL-c. Results: The results showed that the hydroalcoholic extract of Nectaroscordum tripedale could increase the average weight and decrease glucose in this period and also reduce cholesterol levels, triglyceride, and LDL-c dose dependent reduction at the end of 21 days (P <0/05. The hydroalcoholic extract of Nectaroscordum tripedale showed an overall beneficial effect on serum lipid profiles and biochemical factors. Conclusion: Nectaroscordum tripedale may act as an antidiabetic agent by increasing either the pancreatic secretion of insulin from the pancreas or its release from bound insulin and increasing insulin and improving pancreatic function. Moreover, the antioxidant properties may reduce the hydroxy-3-methyl-glutaryl-CoA reductase.

25 CFR 170.144 - What are eligible highway safety projects?

Science.gov (United States)

2010-04-01

... RESERVATION ROADS PROGRAM Indian Reservation Roads Program Policy and Eligibility Highway Safety Functions... management system; (g) Education and outreach highway safety programs, such as use of child safety seats... 25 Indians 1 2010-04-01 2010-04-01 false What are eligible highway safety projects? 170.144...

Development of an automated sequential injection on-line solvent extraction-back extraction procedure as demonstrated for the determination of cadmium with detection by electrothermal atomic absorption spectrometry

DEFF Research Database (Denmark)

Wang, Jianhua; Hansen, Elo Harald

2002-01-01

An automated sequential injection (SI) on-line solvent extraction-back extraction separation/preconcentration procedure is described. Demonstrated for the assay of cadmium by electrothermal atomic absorption spectrometry (ETAAS), the analyte is initially complexed with ammonium pyrrolidinedithioc......An automated sequential injection (SI) on-line solvent extraction-back extraction separation/preconcentration procedure is described. Demonstrated for the assay of cadmium by electrothermal atomic absorption spectrometry (ETAAS), the analyte is initially complexed with ammonium....../preconcentration process of the ensuing sample. An enrichment factor of 21.4, a detection limit of 2.7 ng/l, along with a sampling frequency of 13s/h were obtained at a sample flow rate of 6.0mlmin/sup -1/. The precision (R.S.D.) at the 0.4 mug/l level was 1.8% as compared to 3.2% when quantifying the organic extractant...

Pressurized liquid extracts from Spirulina platensis microalga. Determination of their antioxidant activity and preliminary analysis by micellar electrokinetic chromatography.

Science.gov (United States)

Herrero, Miguel; Ibáñez, Elena; Cifuentes, Alejandro; Señoráns, Javier

2004-08-27

In this work, different extracts from the microalga Spirulina platensis are obtained using pressurized liquid extraction (PLE) and four different solvents (hexane, light petroleum, ethanol and water). Different extraction temperatures (115 and 170 degrees C) were tested using extraction times ranging from 9 to 15 min. The antioxidant activity of the different extracts is determined by means of an in vitro assay using a free radical method. Moreover, a new and fast method is developed using micellar electrokinetic chromatography with diode array detection (MEKC-DAD) to provide a preliminary analysis on the composition of the extracts. This combined application (i.e., in vitro assays plus MEKC-DAD) allowed the fast characterization of the extracts based on their antioxidant activity and the UV-vis spectra of the different compounds found in the extracts. To our knowledge, this work shows for the first time the great possibilities of the combined use of PLE-in vitro assay-MEKC-DAD to investigate natural sources of antioxidants.

Estimation of Dermatological Application of Creams with St. John’s Wort Oil Extracts

Directory of Open Access Journals (Sweden)

Dušanka Runjaić-Antić

2011-12-01

Full Text Available Oleum Hyperici, the oil extract of St. John’s Wort (SJW, is one of the oldest folk remedies, traditionally used in the topical treatment of wounds, bruises, ulcers, cuts, burns, hemorrhoids and also as an antiseptic. Considering the advantageous characteristics of emulsion applications, in the present study we have formulated three O/W creams containing 15% (w/v of SJW oil extract as an active ingredient. The aim was to estimate dermatological application of the prepared creams for the abovementioned indications. The extracts were prepared according to the prescriptions from traditional medicine, however with different vegetable oils used as an extractant, namely: Olive, palm and sunflower oil. The investigated O/W creams demonstrated significant antiinflammatory effects in an in vivo double-blind randomized study, using a sodium lauryl sulphate test. Both skin parameters assessed in the study (electrical capacitance and erythema index, were restored to the baseline value after a seven-day treatment with the tested creams. Almost all investigated SJW oil extracts and corresponding creams displayed the same antimicrobial activity against the most of the investigated microorganisms with obtained minimal inhibitory concentrations values of 1,280 µg/mL, 2,560 µg/mL or >2,560 µg/mL.

High-Resolution Tracking Asymmetric Lithium Insertion and Extraction and Local Structure Ordering in SnS2.

Science.gov (United States)

Gao, Peng; Wang, Liping; Zhang, Yu-Yang; Huang, Yuan; Liao, Lei; Sutter, Peter; Liu, Kaihui; Yu, Dapeng; Wang, En-Ge

2016-09-14

In the rechargeable lithium ion batteries, the rate capability and energy efficiency are largely governed by the lithium ion transport dynamics and phase transition pathways in electrodes. Real-time and atomic-scale tracking of fully reversible lithium insertion and extraction processes in electrodes, which would ultimately lead to mechanistic understanding of how the electrodes function and why they fail, is highly desirable but very challenging. Here, we track lithium insertion and extraction in the van der Waals interactions dominated SnS2 by in situ high-resolution TEM method. We find that the lithium insertion occurs via a fast two-phase reaction to form expanded and defective LiSnS2, while the lithium extraction initially involves heterogeneous nucleation of intermediate superstructure Li0.5SnS2 domains with a 1-4 nm size. Density functional theory calculations indicate that the Li0.5SnS2 is kinetically favored and structurally stable. The asymmetric reaction pathways may supply enlightening insights into the mechanistic understanding of the underlying electrochemistry in the layered electrode materials and also suggest possible alternatives to the accepted explanation of the origins of voltage hysteresis in the intercalation electrode materials.

Optimizing Conditions for Ultrasound Extraction of Fullerenes from Coal Matrices

Czech Academy of Sciences Publication Activity Database

Vítek, P.; Jehlička, J.; Frank, Otakar; Hamplová, Věra; Pokorná, Zdeňka; Juha, Libor; Boháček, J.

2009-01-01

Roč. 17, č. 2 (2009), s. 109-122 ISSN 1536-383X R&D Projects: GA ČR GA205/07/0772; GA ČR GA205/03/1468 Institutional research plan: CEZ:AV0Z40400503; CEZ:AV0Z10100520 Keywords : fullerene C60 * Ultrasound -assisted extraction * Extraction yield * Fullerene decomposition Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 0.710, year: 2009

Traditional Cardiovascular Risk Factors as Predictors of Cardiovascular Events in the U.S. Astronaut Corps

Science.gov (United States)

Halm, M. K.; Clark, A.; Wear, M. L.; Murray, J. D.; Polk, J. D.; Amirian, E.

2009-01-01

Risk prediction equations from the Framingham Heart Study are commonly used to predict the absolute risk of myocardial infarction (MI) and coronary heart disease (CHD) related death. Predicting CHD-related events in the U.S. astronaut corps presents a monumental challenge, both because astronauts tend to live healthier lifestyles and because of the unique cardiovascular stressors associated with being trained for and participating in space flight. Traditional risk factors may not hold enough predictive power to provide a useful indicator of CHD risk in this unique population. It is important to be able to identify individuals who are at higher risk for CHD-related events so that appropriate preventive care can be provided. This is of special importance when planning long duration missions since the ability to provide advanced cardiac care and perform medical evacuation is limited. The medical regimen of the astronauts follows a strict set of clinical practice guidelines in an effort to ensure the best care. The purpose of this study was to evaluate the utility of the Framingham risk score (FRS), low-density lipoprotein (LDL) and high-density lipoprotein levels, blood pressure, and resting pulse as predictors of CHD-related death and MI in the astronaut corps, using Cox regression. Of these factors, only two, LDL and pulse at selection, were predictive of CHD events (HR(95% CI)=1.12 (1.00-1.25) and HR(95% CI)=1.70 (1.05-2.75) for every 5-unit increase in LDL and pulse, respectively). Since traditional CHD risk factors may lack the specificity to predict such outcomes in astronauts, the development of a new predictive model, using additional measures such as electron-beam computed tomography and carotid intima-media thickness ultrasound, is planned for the future.

77 FR 51041 - 30-Day Extension of Call for Nominations for the U.S. Extractive Industries Transparency...

Science.gov (United States)

2012-08-23

... DEPARTMENT OF THE INTERIOR Office of the Secretary [Docket No. ONRR-2012-0003] 30-Day Extension of Call for Nominations for the U.S. Extractive Industries Transparency Initiative Advisory Committee... the United States Extractive Industries Transparency Initiative (USEITI) Multi- Stakeholder Group (MSG...

Measurement of tyrosine kinase activity in non-denaturing polyacrylamide gels and its induction during differentiation of human leukemia HL-60 cells

International Nuclear Information System (INIS)

Glazer, R.I.; Chapekar, M.S.; Knode, M.C.

1986-01-01

The authors have developed a PAGE assay to measure tyrosine kinase (PK-T) activity in cell extracts. HL-60 cells were extracted sequentially with 0.1% and 1.0% Triton X-100 buffer to obtain soluble and membrane-bound proteins, respectively. Extracts were separated by PAGE at 4 0 and gels were incubated in the presence of the substrate Glu:Tyr (4:1) and an assay mixture containing Mn ++ , Mg ++ and [γ 32 P]ATP. Gels were washed in TCA:PPi, dried and autoradiographed. 0.1% Triton extracts of untreated cells in log phase displayed several PK-T activities of which the major species was ∼75 kD; 1% Triton extracts exhibited only residual 75 kD PK-T. In contrast, induction of differentiation in HL-60 cells with optimal concentrations of DMSO, retinoic acid, 1.25(OH) 2 vitamin D 3 , phorbol ester, immune interferon (IFN-γ) or tumor necrosis factor (TNF) induced the appearance of a ∼170 kD PK-T in the 1% Triton extracts and a reduction of the 75 kD PK-T in the 0.1% Triton extracts. The 170 kD PK-T could also utilize Glu:Tyr (6:3:1), histone H 1 , pp60/sup src/ substrate Lys-14-Gly and vinculin as substrates but not Glu:Tyr (1:1). The 170 kD PK-T appeared within 2 days after treatment with 2500 μ/ml of IFN-γ or 100 μ/ml of TNF and its appearance coincided with the induction of the monocyte phenotype. These results suggest that the appearance of the 170 kD PK-T is related to the mature granulocyte or monocyte phenotype. Studies are in progress with radiolabeled IFN-γ to determine if the 170 kD PK-T is related to the IFN-γ receptor

Microwave-assisted extraction of rutin and quercetin from the stalks of Euonymus alatus (Thunb.) Sieb.

Science.gov (United States)

Zhang, Fan; Yang, Yi; Su, Ping; Guo, Zhenku

2009-01-01

Euonymus alatus (Thunb.) has been used as one of traditional Chinese medicines for several thousand years. Conventional methods for the extraction of rutin and quercetin from E. alatus, including solvent extraction, Soxhlet extraction and heat reflux extraction are characterised by long extraction times and consumption of large amounts of solvents. To develop a simple and rapid method for the extraction of rutin and quercetin from the stalks of Euonymus alatus (Thunb.) Sieb using microwave-assisted extraction (MAE) technique. MAE experiments were performed with a multimode microwave extraction system. The experimental variables that affect the MAE process, such as the concentration of ethanol solution, extractant volume, microwave power and extraction time were optimised. Yields were determined by HPLC. The results were compared with that obtained by classical Soxhlet and ultrasonic-assisted extraction (UAE). From the optimised conditions for MAE of rutin and quercetin it can be concluded that the solvent is 50% ethanol (v/v) solution, the extractant volume is 40 mL, microwave power is 170 W and irradiation time is 6 min. Compared with Soxhlet extraction and ultrasonic extraction, microwave extraction is a rapid method with a higher yield and lower solvent consumption. The results showed that MAE can be used as an efficient and rapid method for the extraction of the active components from plants.

Effect of the temperature on the spray drying of Roselle extracts (Hibiscus sabdariffa L.).

Science.gov (United States)

Gonzalez-Palomares, Salvador; Estarrón-Espinosa, Mirna; Gómez-Leyva, Juan Florencio; Andrade-González, Isaac

2009-03-01

The effect of the drying temperature on the volatile components and sensory acceptance of the Roselle (Hibiscus sabdariffa) extract in powder was investigated. The Roselle extraction was carried out by maceration with 7 L of 30% ethanol (v/v), 560 g of fresh Roselle calyces for 168 h. The Roselle extracts were spray dried at different temperatures 150, 160, 170, 180, 190, 200 and 210 degrees C, giving different outlet values about yield and final moisture. The volatile compounds in Roselle extract and dried samples were performed using needles of solid phase microextraction (SPME) and gas chromatography/mass spectrometry (GC/MS HP-5890). Twenty volatile compounds were identified in the extracts among them terpenoids, esters, hydrocarbons and aldehydes. Fourteen volatile compounds were identified in the powder sample, but only ten were present in the Roselle extract. This indicates that some compounds were lost and some others were generated due to a degradation process. An acceptability sensory analysis showed that the best powder sample was the Roselle extract dehydrated using temperature between 190 degrees C and 200 degrees C (pRoselle extracts ranging from 3.4 to 3.9. It was concluded that the spray drying temperature of the Roselle extracts has an effect on the volatile compounds losses.

Identification of a Gypsy SHOX mutation (p.A170P) in Léri-Weill dyschondrosteosis and Langer mesomelic dysplasia.

Science.gov (United States)

Barca-Tierno, Verónica; Aza-Carmona, Miriam; Barroso, Eva; Heine-Suner, Damia; Azmanov, Dimitar; Rosell, Jordi; Ezquieta, Begoña; Montané, Lucia Sentchordi; Vendrell, Teresa; Cruz, Jaime; Santos, Fernando; Rodríguez, José Ignacio; Pozo, Jesús; Argente, Jesús; Kalaydjieva, Luba; Gracía, Ricardo; Campos-Barros, Angel; Benito-Sanz, Sara; Heath, Karen E

2011-12-01

We report the clinical and molecular characteristics of 12 Spanish families with multiple members affected with Léri-Weill dyschondrosteosis (LWD) or Langer mesomelic dysplasia (LMD), who present the SHOX (short stature homeobox gene) mutation p.A170P (c.508G>C) in heterozygosity or homozygosity, respectively. In all studied families, the A170P mutation co-segregated with the fully penetrant phenotype of mesomelic limb shortening and Madelung deformity. A shared haplotype around SHOX was observed by microsatellite analysis, confirming the presence of a common ancestor, probably of Gypsy origin, as 11 of the families were of this ethnic group. Mutation screening in 359 Eastern-European Gypsies failed to identify any carriers. For the first time, we have shown SHOX expression in the human growth plate of a 22-week LMD fetus, homozygous for the A170P mutation. Although the mutant SHOX protein was expressed in all zones of the growth plate, the chondrocyte columns in the proliferative zone were disorganized with the chondrocytes occurring in smaller columnal clusters. We have also identified a novel mutation at the same residue, c. 509C>A (p.A170D), in two unrelated Spanish LWD families, which similar to A170P mutation impedes nuclear localization of SHOX. In conclusion, we have identified A170P as the first frequent SHOX mutation in Gypsy LWD and LMD individuals.

Optimization of continuous and intermittent microwave extraction of pectin from banana peels.

Science.gov (United States)

Swamy, Gabriela John; Muthukumarappan, Kasiviswanathan

2017-04-01

Continuous and intermittent microwave-assisted extractions were used to extract pectin from banana peels. Extraction parameters which were employed in the continuous process were microwave power (300-900W), time (100-300s), pH (1-3) and in the intermittent process were microwave power (300-900W), pulse ratio (0.5-1), pH (1-3). The independent factors were optimized with the Box-Behnken response surface design (BBD) (three factor three level) with the desirability function methodology. Results indicate that the independent factors have substantial effect on the pectin yield. Optimized solutions for highest pectin yield (2.18%) from banana peels were obtained with microwave power of 900W, time 100s and pH 3.00 in the continuous method while the intermittent process yielded the highest pectin content (2.58%) at microwave power of 900W, pulse ratio of 0.5 and pH of 3.00. The optimized conditions were validated and close agreement was observed with the validation experiment and predicted value. Copyright © 2016 Elsevier Ltd. All rights reserved.

Initial results for a 170 GHz high power ITER waveguide component test stand

Science.gov (United States)

Bigelow, Timothy; Barker, Alan; Dukes, Carl; Killough, Stephen; Kaufman, Michael; White, John; Bell, Gary; Hanson, Greg; Rasmussen, Dave

2014-10-01

A high power microwave test stand is being setup at ORNL to enable prototype testing of 170 GHz cw waveguide components being developed for the ITER ECH system. The ITER ECH system will utilize 63.5 mm diameter evacuated corrugated waveguide and will have 24 >150 m long runs. A 170 GHz 1 MW class gyrotron is being developed by Communications and Power Industries and is nearing completion. A HVDC power supply, water-cooling and control system has been partially tested in preparation for arrival of the gyrotron. The power supply and water-cooling system are being designed to operate for >3600 second pulses to simulate the operating conditions planned for the ITER ECH system. The gyrotron Gaussian beam output has a single mirror for focusing into a 63.5 mm corrugated waveguide in the vertical plane. The output beam and mirror are enclosed in an evacuated duct with absorber for stray radiation. Beam alignment with the waveguide is a critical task so a combination of mirror tilt adjustments and a bellows for offsets will be provided. Analysis of thermal patterns on thin witness plates will provide gyrotron mode purity and waveguide coupling efficiency data. Pre-prototype waveguide components and two dummy loads are available for initial operational testing of the gyrotron. ORNL is managed by UT-Battelle, LLC, for the U.S. Dept. of Energy under Contract DE-AC-05-00OR22725.

Microencapsulation of Theobroma cacao L. waste extract: optimization using response surface methodology.

Science.gov (United States)

Gabbay Alves, Taís Vanessa; Silva da Costa, Russany; Aliakbarian, Bahar; Casazza, Alessandro Alberto; Perego, Patrizia; Carréra Silva Júnior, José Otávio; Ribeiro Costa, Roseane Maria; Converti, Attilio

2017-03-01

The cocoa extract (Theobroma cacao L.) has a significant amount of polyphenols (TP) with potent antioxidant activity (AA). This study aims to optimise microencapsulation of the extract of cocoa waste using chitosan and maltodextrin. Microencapsulation tests were performed according to a Box-Behnken factorial design, and the results were evaluated by response surface methodology with temperature, maltodextrin concentration (MD) and extract flowrate (EF) as independent variables, and the fraction of encapsulated TP, TP encapsulation yield, AA, yield of drying and solubility index as responses. The optimum conditions were: inlet temperature of 170 °C, MD of 5% and EF of 2.5 mL/min. HPLC analysis identified epicatechin as the major component of both the extract and microparticles. TP release was faster at pH 3.5 than in water. These results as a whole suggest that microencapsulation was successful and the final product can be used as a nutrient source for aquatic animal feed. Highlights Microencapsulation is optimised according to a factorial design of the Box-Behnken type. Epicatechin is the major component of both the extract and microcapsules. The release of polyphenols from microcapsules is faster at pH 3.5 than in water.

Extraction method

International Nuclear Information System (INIS)

Stary, J.; Kyrs, M.; Navratil, J.; Havelka, S.; Hala, J.

1975-01-01

Definitions of the basic terms and of relations are given and the knowledge is described of the possibilities of the extraction of elements, oxides, covalent-bound halogenides and heteropolyacids. Greatest attention is devoted to the detailed analysis of the extraction of chelates and ion associates using diverse agents. For both types of compounds detailed conditions are given of the separation and the effects of the individual factors are listed. Attention is also devoted to extractions using mixtures of organic agents, the synergic effects thereof, and to extractions in non-aqueous solvents. The effects of radiation on extraction and the main types of apparatus used for extractions carried out in the laboratory are described. (L.K.)

25 CFR 170.623 - How are IRR Program projects and activities included in a self-governance agreement?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false How are IRR Program projects and activities included in a self-governance agreement? 170.623 Section 170.623 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE... self-governance agreement? To include an IRR Program project or activity in a self-governance agreement...

26 CFR 1.509(a)-2 - Exclusion for certain organizations described in section 170(b)(1)(A).

Science.gov (United States)

2010-04-01

... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Exclusion for certain organizations described in....509(a)-2 Exclusion for certain organizations described in section 170(b)(1)(A). (a) General rule. Organizations described in section 170(b)(1)(A) (other than in clauses (vii) and (viii)) are excluded from the...

Charmless B{sub (s)} → VV decays in factorization-assisted topological-amplitude approach

Energy Technology Data Exchange (ETDEWEB)

Wang, Chao; Zhang, Qi-An [CAS, Institute of High Energy Physics, P.O. Box 918, Beijing (China); University of Chinese Academy of Sciences, School of Physics, Beijing (China); Li, Ying [Yantai University, Department of Physics, Yantai (China); CAS, State Key Laboratory of Theoretical Physics, Institute of Theoretical Physics, Beijing (China); Lue, Cai-Dian [CAS, Institute of High Energy Physics, P.O. Box 918, Beijing (China); University of Chinese Academy of Sciences, School of Physics, Beijing (China); CAS, State Key Laboratory of Theoretical Physics, Institute of Theoretical Physics, Beijing (China)

2017-05-15

Within the factorization-assisted topological-amplitude approach, we studied the 33 charmless B{sub (s)} → VV decays, where V stands for a light vector meson. According to the flavor flows, the amplitude of each process can be decomposed into eight different topologies. In contrast to the conventional flavor diagrammatic approach, we further factorize each topological amplitude into decay constant, form factors and unknown universal parameters. By χ{sup 2} fitting 46 experimental observables, we extracted 10 theoretical parameters with χ{sup 2} per degree of freedom around 2. Using the fitted parameters, we calculated the branching fractions, polarization fractions, CP asymmetries and relative phases between polarization amplitudes of each decay mode. The decay channels dominated by tree diagram have large branching fractions and large longitudinal polarization fraction. The branching fractions and longitudinal polarization fractions of color-suppressed decays become smaller. Current experimental data of large transverse polarization fractions in the penguin dominant decay channels can be explained by only one transverse amplitude of penguin annihilation diagram. Our predictions of the not yet measured channels can be tested in the ongoing LHCb experiment and the Belle-II experiment in the future. (orig.)

Comparative Assay of Glutathione S- Transferase (GSTs Activity of Excretory-Secretory Materials and Somatic Extract of Fasciola spp Parasites

Directory of Open Access Journals (Sweden)

Heshmatollah Alirahmi

2010-12-01

Full Text Available Fascioliasis is a worldwide parasitic disease in human and domestic animals. The causative agents of fascioliasis are Fasciola hepatica and Fasciola gigantica. In the recent years, fasciola resistance to drugs has been reported in the many of publications. Fasciola spp has detoxification system including GST enzyme which may be responsible for its resistance. Therefore , the aim of the study was to assay of GST enzyme activity in fasciola parasites. Fasciola gigantica and Fasciola hepatica helminths were collected from abattoir as a live and cultured in buffer media for 4 h at 37 °C. Excretory-Secretory products were collected and stored in -80◦C. F. gigantica and Fasciola hepatica were homogenized with homogenizing buffer in a glass homogenizer to prepare of somatic extract. Suspension was then centrifuged and supernatant was stored at -80°C. In order to assay the enzyme activity, excretory-secretory and somatic extracts in the form of cocktails (potassium phosphate buffer, reduced glutathione and 1-chloro-2,4-dinitrobenzene substrates were prepared and their absorbance recorded for 5 minutes at 340 nm. The total and specific GST activity of F. gigantica somatic and ES products were obtained as 2916.00, 272.01 micromole/minute and 1.33, 1.70 micromole/minute/mg protein, respectively. Fasciola hepatica also showed 2705.00, 276.86 micromole/minute and 1.33, 1.52 micromole/minute/mg protein, respectively. These results are important for analysis of parasite survival / resistance to drugs which use for treatment of fascioliasis.

Comparative Assay of Glutathione S- Transferase (GSTs Activity of Excretory-Secretory Materials and Somatic Extract of Fasciola spp Parasites

Directory of Open Access Journals (Sweden)

Taghi Golmohamadi

2010-11-01

Full Text Available Fascioliasis is a worldwide parasitic disease in human and domestic animals. The causative agents of fascioliasis are Fasciola hepatica and Fasciola gigantica. In the recent years, fasciola resistance to drugs has been reported in the many of publications. Fasciola spp has detoxification system including GST enzyme which may be responsible for its resistance. Therefore , the aim of the study was to assay of GST enzyme activity in fasciola parasites. Fasciola gigantica and Fasciola hepatica helminths were collected from abattoir as a live and cultured in buffer media for 4 h at 37 °C. Excretory-Secretory products were collected and stored in -80◦C. F. gigantica and Fasciola hepatica were homogenized with homogenizing buffer in a glass homogenizer to prepare of somatic extract. Suspension was then centrifuged and supernatant was stored at -80°C. In order to assay the enzyme activity, excretory-secretory and somatic extracts in the form of cocktails (potassium phosphate buffer, reduced glutathione and 1-chloro-2,4-dinitrobenzene substrates were prepared and their absorbance recorded for 5 minutes at 340 nm. The total and specific GST activity of F. gigantica somatic and ES products were obtained as 2916.00, 272.01 micromole/minute and 1.33, 1.70 micromole/minute/mg protein, respectively. Fasciola hepatica also showed 2705.00, 276.86 micromole/minute and 1.33, 1.52 micromole/minute/mg protein, respectively. These results are important for analysis of parasite survival / resistance to drugs which use for treatment of fascioliasis.

N. S. LESKOV’S NOTEBOOK WITH EXTRACTS FROM “PROLOGUE” (THE EXPERIENCE OF TEXTUAL COMMENTS

Directory of Open Access Journals (Sweden)

Inna N. Mineeva

2016-03-01

Full Text Available Thе article, for the fi rst time, provides a detailed textual commentary on N. S. Leskov’s notebook with extracts from “Prologue”. The extant literary materials include extracts and abstracts from the early printed Prologue, fi ction and historical literature of the 19th century, letters of European and Russian scholars and authors (Pushkin A., Tolstoy L., Pigault-Lebrun, Sher I., devoted to  doctrine matters and religious aspects, description and analysis of anthropologic categories. The autograph is the evidence of spiritual search and creative experiments of  the writer. In  the books the  writer found endorsement of both his own ideas, and those ones that require further inner understanding, questioning and emotional upheaval. Meanwhile, studying the history, structure and contents of  Prologue in  the 1880s, Leskov found an  exceptional existential and creative experience. The most part of  the notebook shows the writer’s learning process of various examples of repentance, atonement, a sudden rebirth of a sinner, active love, the benefi ts of obedience, the miracle of movement of a saint in space, the phenomenon of manifestation of  supernatural power and its intervention in  life of  a  man (God, the Holy Spirit, Angels, etc. While working with Prologue texts Leskov enunciated some principles of  their artistic processing  (quoting “crisis”, “turning”, unusual fragments in  the Church Slavonic language, emphasizing key situations by changing the name, specifying the narration, acronyms, graphic intonation. General trends in  understanding of  the  Prologue source (ideological, imaginative, plot-compositional, stylistic, identifi ed in the notebook, are subsequently transformed by the author in a series of “Byzantine Legends” where they receive additional semantic and functional load.

Leaf Extracts of Mangifera indica L. Inhibit Quorum Sensing – Regulated Production of Virulence Factors and Biofilm in Test Bacteria

Directory of Open Access Journals (Sweden)

Iqbal Ahmad

2017-04-01

Full Text Available Quorum sensing (QS is a global gene regulatory mechanism in bacteria for various traits including virulence factors. Disabling QS system with anti-infective agent is considered as a potential strategy to prevent bacterial infection. Mangifera indica L. (mango has been shown to possess various biological activities including anti-QS. This study investigates the efficacy of leaf extracts on QS-regulated virulence factors and biofilm formation in Gram negative pathogens. Mango leaf (ML extract was tested for QS inhibition and QS-regulated virulence factors using various indicator strains. It was further correlated with the biofilm inhibition and confirmed by electron microscopy. Phytochemical analysis was carried out using ultra performance liquid chromatography (UPLC and gas chromatography–mass spectrometry (GC-MS analysis. In vitro evaluation of anti-QS activity of ML extracts against Chromobacterium violaceum revealed promising dose-dependent interference in violacein production, by methanol extract. QS inhibitory activity is also demonstrated by reduction in elastase (76%, total protease (56%, pyocyanin (89%, chitinase (55%, exopolysaccharide production (58% and swarming motility (74% in Pseudomonas aeruginosa PAO1 at 800 μg/ml concentration. Biofilm formation by P. aeruginosa PAO1 and Aeromonas hydrophila WAF38 was reduced considerably (36–82% over control. The inhibition of biofilm was also observed by scanning electron microscopy. Moreover, ML extracts significantly reduced mortality of Caenorhabditis elegans pre-infected with PAO1 at the tested concentration. Phytochemical analysis of active extracts revealed very high content of phenolics in methanol extract and a total of 14 compounds were detected by GC-MS and UPLC. These findings suggest that phytochemicals from the ML could provide bioactive anti-infective and needs further investigation to isolate and uncover their therapeutic efficacy.

Leaf Extracts of Mangifera indica L. Inhibit Quorum Sensing – Regulated Production of Virulence Factors and Biofilm in Test Bacteria

Science.gov (United States)

Husain, Fohad M.; Ahmad, Iqbal; Al-thubiani, Abdullah S.; Abulreesh, Hussein H.; AlHazza, Ibrahim M.; Aqil, Farrukh

2017-01-01

Quorum sensing (QS) is a global gene regulatory mechanism in bacteria for various traits including virulence factors. Disabling QS system with anti-infective agent is considered as a potential strategy to prevent bacterial infection. Mangifera indica L. (mango) has been shown to possess various biological activities including anti-QS. This study investigates the efficacy of leaf extracts on QS-regulated virulence factors and biofilm formation in Gram negative pathogens. Mango leaf (ML) extract was tested for QS inhibition and QS-regulated virulence factors using various indicator strains. It was further correlated with the biofilm inhibition and confirmed by electron microscopy. Phytochemical analysis was carried out using ultra performance liquid chromatography (UPLC) and gas chromatography–mass spectrometry (GC-MS) analysis. In vitro evaluation of anti-QS activity of ML extracts against Chromobacterium violaceum revealed promising dose-dependent interference in violacein production, by methanol extract. QS inhibitory activity is also demonstrated by reduction in elastase (76%), total protease (56%), pyocyanin (89%), chitinase (55%), exopolysaccharide production (58%) and swarming motility (74%) in Pseudomonas aeruginosa PAO1 at 800 μg/ml concentration. Biofilm formation by P. aeruginosa PAO1 and Aeromonas hydrophila WAF38 was reduced considerably (36–82%) over control. The inhibition of biofilm was also observed by scanning electron microscopy. Moreover, ML extracts significantly reduced mortality of Caenorhabditis elegans pre-infected with PAO1 at the tested concentration. Phytochemical analysis of active extracts revealed very high content of phenolics in methanol extract and a total of 14 compounds were detected by GC-MS and UPLC. These findings suggest that phytochemicals from the ML could provide bioactive anti-infective and needs further investigation to isolate and uncover their therapeutic efficacy. PMID:28484444

Processing of the 17-S Escherichia coli precursor RNA in the 27-S pre-ribosomal particle

Energy Technology Data Exchange (ETDEWEB)

Hayes, F; Vasseur, M [Institut de Biologie Physico-Chimique, 75 - Paris (France)

1976-01-01

An RNase activity probably involved in the maturation of 16-S pre-ribosomal RNA in Escherichia coli has been partially purified from crude cell extracts. When 27-S ribosome precursor particles are incubated with this enzyme preparation in vitro, their 17-S RNA is converted to a product with the same electrophoretic mobility as mature 16-S rRNA. FingerprS rRNA. Generation of the normal 5'-P terminus seems to require a factor present in cell extracts since incubation of the 27-S precursor particle in an extract obtained after centrifugation at 30,000 x g causes conversion of the 17-S RNA to a 16-S species containing both termini of mature 16-S rRNS. Preliminary experiments suggest that correct maturation of the 5' end of the 17-S precursor RNA requires a system in which protein synthesis can take place.

The N170 is not modulated by attention in autism spectrum conditions.

Science.gov (United States)

Churches, Owen; Wheelwright, Sally; Baron-Cohen, Simon; Ring, Howard

2010-04-21

Face processing deficits are characteristic of autism spectrum conditions. However, event-related potential studies of autism spectrum conditions have found inconsistent results for the face selective N170 component. In this study, 15 adult males with autism spectrum conditions and 15 matched, typically developing controls completed a task in which pictures of faces were either attended to or ignored. In the control group, the N170 was larger when faces were attended to. However, there was no such modulation in the autism spectrum conditions group. This finding helps clarify the results from the earlier event-related potential studies of face processing in autism spectrum conditions and suggests that visual attention does not enhance face processing in autism spectrum conditions as it does in typical development.

Impact of geotechnical factors on the secondary extraction of coal in the Witbank and Northern Highveld Coalfields, specifically related to safety.

CSIR Research Space (South Africa)

Jeffrey, JS

2002-04-01

Full Text Available This report describes a literature review that identified geotechnical factors impacting on unplanned secondary coal extraction. These factors are grouped into nine broad classes of factors; namely, stratigraphy, rock /coal engineering properties...

Charge-symmetry-breaking nucleon form factors

International Nuclear Information System (INIS)

Kubis, Bastian

2011-01-01

A quantitative understanding of charge-symmetry breaking is an increasingly important ingredient for the extraction of the nucleon’s strange vector form factors. We review the theoretical understanding of the charge-symmetry-breaking form factors, both for single nucleons and for 4 He.

The effect of cynanchi wilfordii radix ethanol extracts upon irradiated rat's blood and organ

Energy Technology Data Exchange (ETDEWEB)

Kim, Jang Oh; Choi, Jun Hyeok; Shin, Ji Hye; Min, Byung In [Inje University, Kimhae (Korea, Republic of); Jung, Do Young [Dept. of Radiation Oncology, Dongnam Institute of Radiological and Medical Sciences Cancer Center, Busan (Korea, Republic of)

2016-09-15

The development of radioprotector is being actively conducted in order to reduce the damage from over radiation exposure at radiation accident or radiation therapy. So this study was confirmed for radiation protective effects using the Cynanchi wilfordii Radix that has been known to be effective for antioxidant activity, anti-cancer, immune enhancing effects. The method of this study was administered orally Cynanchi wilfordii Radix ethanol extracts to Sprague Dawley Rat(SD Rat) for 14 days once a day, while measuring changed blood cell, spleen index, liver and uterus tissue along the change in time of 1, 4, 7 and 21 days after X-ray beam of 7 Gy irradiation. As the result of the experiment, the experimental group's rats which are administered with Cynanchi Wilfordii Radix ethanol extracts showed a rapid recovery in white blood cell count(p < 0.05) and spleen index(p < 0.05). In addition, condensation of nuclei, cytoplasmic swelling, and inflammatory cell infiltration in experimental group's liver cell was decreased more than in irradiation group's component. Further, experimental group's Uterine gland decreased the apoptosis more than irradiation group's components did. It is expected that Cynanchi Wilfordii Radix extracts will be useful as a new radioprotector. With above in mind, this paper may provide appropriate implications with the field of emergency management such as radiation accident.

Optimization of the microwave-assisted extraction of phlorotannins from Saccharina japonica Aresch and evaluation of the inhibitory effects of phlorotannin-containing extracts on HepG2 cancer cells

Science.gov (United States)

He, Zhizhou; Chen, Yongshun; Chen, Yongheng; Liu, Haohuai; Yuan, Guanfu; Fan, Yaming; Chen, Kun

2013-09-01

The use of a microwave-assisted extraction (MAE) method for the extraction of phlorotannins from Saccharina japonica Aresch ( S. japonica) has been evaluated with particular emphasis on the influential parameters, including the ethanol concentration, solid/liquid ratio, extraction time, extraction temperature, and microwave power. The MAE procedure was optimized using single-factor design and orthogonal array design (OAD). The content of total phlorotannins in S. japonica was determined using a Folin-Ciocalteu (FC) assay. A maximum total phlorotannin content of 0.644 mg of phloroglucinol equivalent per gram of dry weight plant (mg PGE/g DW) was obtained using the optimized model, which included an ethanol concentration of 55%, solid/liquid ratio of 1:8, extraction time of 25 min, irradiation power of 400 W, and temperature of 60°C. Under similar conditions, the application of a conventional extraction method led to a lower phlorotannin yield of 0.585 mg PGE/g WD. These results demonstrated that the MAE approach provided better results for the extraction of phlorotannins from S. japonica and was a promising technique for the extraction of phenolic compounds from S. japonica and other materials. In addition, screening tests for the inhibitory activity showed that the phlorotannin-containing extracts significantly inhibited the growth of human hepatocellular carcinoma cells (HepG2) by inducing their apoptosis. The morphological changes that occurred during cell apoptosis were characterized using Hoechst33258 staining.

Factors influencing the thermodynamic isotope effect of lithium in polyetherlithium liquid-liquid extraction systems

International Nuclear Information System (INIS)

Fu Lian; Fang Shengqiang; Yao Zhongqi; Gao Zhichang; Tan Ganzhu

1989-01-01

The published data up to now concerning polyether-lithium liquid-liquid extraction systems, can be summarized by the equation, ε p = (α-1)/[1 + 0.46(1-P)], where α denotes the isotope separation factor; P - the ratio of the lithium concentration in the organic phase to the initial concentration of crown ethers; ε p -the enrichment coefficient as P = 100%. Based on the changes in ε p , P, α and D(distribution ratio), the functions of factors such as polyether's structure, polyether's side group, polyether's concentration, organic solvent, negative ion of lithium salt and lithium salt's concentration, are discussed and reported

Antimicrobial efficacy of Syzygium antisepticum plant extract against Staphylococcus aureus and methicillin-resistant S. aureus and its application potential with cooked chicken.

Science.gov (United States)

Yuan, Wenqian; Yuk, Hyun-Gyun

2018-06-01

For the past decades, there has been a growing demand for natural antimicrobials in the food industry. Plant extracts have attracted strong research interests due to their wide-spectrum antimicrobial activities, but only a limited number have been investigated thoroughly. The present study aimed at identifying a novel anti-staphylococcal plant extract, to validate its activity in a food model, and to investigate on its composition and antimicrobial mechanism. Four plant extracts were evaluated against Staphylococcus aureus and methicillin-resistant S. aureus (MRSA) in vitro, with Syzygium antisepticum leaf extract showing the strongest antimicrobial activity (MIC = 0.125 mg/mL). Relatively high total phenolic content (276.3 mg GAE/g extract) and antioxidant activities (90.2-138.0 mg TE/g extract) were measured in S. antisepticum extract. Food validation study revealed that higher extract concentration (32 mg/mL) was able to inhibit or reduce staphylococcal growth in cooked chicken, but caused color change on meat surface. By GC-MS, β-caryophyllene (12.76 area%) was identified as the dominant volatile compound in extract. Both crude extract and pure β-caryophyllene induced membrane damages in S. aureus. These results suggested good anti-staphylococcal properties of S. antisepticum plant extract, identified its major volatile composition and its membrane-damaging antimicrobial mechanism. Copyright © 2017 Elsevier Ltd. All rights reserved.

46 CFR 170.270 - Door design, operation, installation, and testing.

Science.gov (United States)

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Door design, operation, installation, and testing. 170..., operation, installation, and testing. (a) Each Class 1 door must have a quick action closing device... the welding process so that the door frame is not distorted. (e) For each watertight door which is in...

Enhanced biocompatibility of ZnS:Mn quantum dots encapsulated with Aloe vera extract for therapeutic applications

International Nuclear Information System (INIS)

Anilkumar, M; Sneha Saj, A; Bindu, K R; Anila, E I

2016-01-01

Toxicity of nanoparticles remains to be a major issue in their application to the biomedical field. Aloe vera (AV) is one of the most widely exploited medicinal plants that have a multitude of amazing properties in the field of medicine. Methanol extract of Aloe vera can be used as a novel stabilising agent for quantum dots to reduce toxicity. We report the synthesis, structural characterization, antibacterial activity and cytotoxicity studies of ZnS:Mn quantum dots synthesized by the colloidal precipitation method, using methanol extract of Aloe vera (AVME) as the capping agent. The ZnS:Mn quantum dots capped with AVME exhibit superior performances in biocompatibility and antibacterial activity compared with ZnS:Mn quantum dots without encapsulation. (paper)

Combined Effects of Inversion and Feature Removal on N170 Responses Elicited by Faces and Car Fronts

Science.gov (United States)

Kloth, Nadine; Itier, Roxane J.; Schweinberger, Stefan R.

2013-01-01

The face-sensitive N170 is typically enhanced for inverted compared to upright faces. Itier, Alain, Sedore, and McIntosh (2007) recently suggested that this N170 inversion effect is mainly driven by the eye region which becomes salient when the face configuration is disrupted. Here we tested whether similar effects could be observed with non-face…

Subcritical water extraction of phenolic and antioxidant constituents from pistachio (Pistacia vera L.) hulls.

Science.gov (United States)

Erşan, Sevcan; Güçlü Üstündağ, Özlem; Carle, Reinhold; Schweiggert, Ralf M

2018-07-01

Pistachio hulls, important by-products of pistachio processing, were extracted using an environmentally friendly process with subcritical water (SCW) at a pressure of 6.9 MPa in the range of 110 and 190 °C, and a flow rate of 4 ml/min. Detailed HPLC-DAD-ESI/MS n analyses allowed the identification of 49 phenolic compounds in the SCW extracts. Total gallotannin yields up to 33 g/kg were reached at 150-170 °C, where gallic acid (22.2 g/kg) and penta-O-galloyl-β-d-glucose (9.77 g/kg) levels were 13.2- and 10.6-fold higher than those in the aqueous methanol extracts. Flavonols were also effectively extracted at 110-150 °C (4.37-5.65 g/kg), while anacardic acid recovery was poor (1.13-2.77 g/kg). Accordingly, high amounts of anacardic acids (up to 50.7 g/kg) were retained in the extraction residue, revealing that SCW extraction allowed selective extraction of gallotannins and flavonols. Antioxidant capacities ranged from 0.68 to 1.20 mmol Trolox equivalents (TE)/g for SCW extracts increasing with temperature up 190 °C. Copyright © 2018 Elsevier Ltd. All rights reserved.

In situ Orbit Extraction from Live, High Precision Collisionless Simulations of Systems Formed by Cold Collapse

Science.gov (United States)

Noriega-Mendoza, H.; Aguilar, L. A.

2018-04-01

We performed high precision, N-body simulations of the cold collapse of initially spherical, collisionless systems using the GYRFALCON code of Dehnen (2000). The collapses produce very prolate spheroidal configurations. After the collapse, the systems are simulated for 85 and 170 half-mass radius dynamical timescales, during which energy conservation is better than 0.005%. We use this period to extract individual particle orbits directly from the simulations. We then use the TAXON code of Carpintero and Aguilar (1998) to classify 1 to 1.5% of the extracted orbits from our final, relaxed configurations: less than 15% are chaotic orbits, 30% are box orbits and 60% are tube orbits (long and short axis). Our goal has been to prove that direct orbit extraction is feasible, and that there is no need to "freeze" the final N-body system configuration to extract a time-independent potential.

Infrastructure for thulium-170 isotope power systems for autonomous underwater vehicle fleets

International Nuclear Information System (INIS)

Walter, C.E.

1991-07-01

The radioisotope thulium-170 is a safe and environmentally benign heat source for providing the high endurance and energy densities needed by advanced power systems for autonomous underwater vehicles (AUV). Thulium Isotope Power (TIP) systems have an endurance of ∼3000 h, and gravimetric and volumetric energy densities of 3 x 10 4 Wh/kg and 3 x 10 8 Wh/m 3 , respectively. These energy densities are more than 200 times higher than those currently provided by Ag-Zn battery technology. In order to capitalize on these performance levels with about one hundred AUVs in continuous use, it will be necessary to establish an infrastructure for isotope production and heat-source refurbishment. The infrastructure cost is not trivial, and studies are needed to determine its optimum configuration. The major component of the projected infrastructure is the nuclear reactor used to produce Tm- 170 by neutron absorption in Tm-169. The reactor design should ideally be optimized for TM-170 production. Using the byproduct ''waste'' heat beneficially would help defray the cost of isotope production. However, generating electric power with the reactor would compromise both the cost of electricity and the isotope production capacity. A coastal location for the reactor would be most convenient from end-use considerations, and the ''waste'' heat could be used to desalinate seawater in water-thirsty states. 13 refs., 6 figs., 2 tabs

IMPACTS, PATTERNS, INFLUENCING FACTORS AND POLICIES OF FUELWOOD EXTRACTION IN WAY KAMBAS NATIONAL PARK, INDONESIA

Directory of Open Access Journals (Sweden)

Ari Rakatama

2016-04-01

Full Text Available Uncontrolled fuelwood extraction from conservation forest of Way Kambas National Park (WKNP could threaten the existing forest. This paper studies the way to tackle the forest degradation in WKNP, with less negative impacts to the local people. Study was conducted by analysing existing data and maps of WKNP in terms of forest degradation, forest inventories, current policies, survey on how fuelwood is extracted, observation on fuelwood gatherers, fuelwood demand, and identification of further policy options. Results show that the most significant factors influencing the fuelwood extraction activity in WKNP are land ownership, followed by the distance to forest area, income level, the number of household members and age of household head. In the field, the fuelwood utilization is allowed by WKNP Authority, although it is formally forbidden.It was stated that fuelwood extraction in the area should be less than 2.89 ton/ha/year to maintain its sustainability, based on the mean WNKP forest tree annual increment. The fact shows that fuelwood extraction in WKNP reduces of forest biomass stock (1.06 tons/ha/year and decreases species diversity index (from 3.05 to 2.45, species evenness index (from 1.06 to 0.91 and old-young tree ratio (from 1.29 to 1. Ecosystem quality reduction is mainly caused by destructive techniques in extracting fuelwood such as slashing, scratching cambium, and cutting trees. Therefore, recommended policy includes legalizing fuelwood extraction with restrictions, providing alternative fuelwood and other biomass energy resources outside WKNP, conducting preventive (establishing checkpoints and increasing patrols and pre-emptive (educating and campaigning efforts, collaborating with other stakeholders, and empowering local economy.

Charge-symmetry-breaking nucleon form factors

Energy Technology Data Exchange (ETDEWEB)

Kubis, Bastian, E-mail: kubis@hiskp.uni-bonn.de [Universitaet Bonn, Helmholtz-Institut fuer Strahlen- und Kernphysik (Theorie) and Bethe Center for Theoretical Physics (Germany)

2011-11-15

A quantitative understanding of charge-symmetry breaking is an increasingly important ingredient for the extraction of the nucleon's strange vector form factors. We review the theoretical understanding of the charge-symmetry-breaking form factors, both for single nucleons and for {sup 4}He.

7 CFR 3015.170 - Damage, loss, or theft of equipment.

Science.gov (United States)

2010-01-01

... 7 Agriculture 15 2010-01-01 2010-01-01 false Damage, loss, or theft of equipment. 3015.170 Section... Damage, loss, or theft of equipment. (a) Applicability. This section applies to equipment with a unit... damage, loss, or theft, the recipient does not have a control system in effect as required by § 3015.169...

When rapid adaptation paradigm is not too rapid: Evidence of face-sensitive N170 adaptation effects.

Science.gov (United States)

Tian, Tengxiang; Feng, Xue; Feng, Chunliang; Gu, Ruolei; Luo, Yue-Jia

2015-07-01

Recent findings have demonstrated that N170 adaptation effects evoked by face adaptors are general to face and non-face tests, implicating adaptor-locked interferences in the rapid adaptation paradigm. Here we examined the extent to which adaptor-locked interferences confound N170 adaptation effects in different experimental parameters by manipulating the stimulus onset asynchrony (SOA) duration and jitter between adaptors and tests. In the short SOA, those interferences were well visible for the grand-average ERP waveforms evoked by tests, and they are likely to render rapid adaptation paradigm with short SOA unreliable. The adaptor-locked interferences were attenuated by appropriately increasing SOA duration, such that face-sensitive adaptation effects were evident in the long SOA for both baseline-to-peak and peak-to-peak N170 measurements. These findings suggest that the rapid adaptation paradigm may work with a relative long SOA. Our findings provide useful information for future studies regarding the choosing of appropriate experimental parameters and measurements for the rapid adaptation paradigm. In addition, future studies are needed to investigate how to objectively subtract the overlaps of adaptors from tests and to validate the N170 adaptation effect with appropriate behavioral performance. Copyright © 2015 Elsevier B.V. All rights reserved.

Using growth factors in human extraction sockets: a histologic and histomorphometric evaluation of short-term healing

NARCIS (Netherlands)

Geurs, N.; Ntounis, A.; Vassilopoulos, P.; van der Velden, U.; Loos, B.G.; Reddy, M.

2014-01-01

Purpose: Ridge preservation protocols reduce crestal remodeling after tooth extraction. There is insufficient evidence on bone grafting in combination with platelet-rich plasma (PRP) or recombinant human platelet-derived growth factor (rhPDGF-BB). The aim of this study is to evaluate healing of

Factors that influencing veterinary drug’s metabolisation

Directory of Open Access Journals (Sweden)

Cristina, Romeo T.

2007-12-01

Full Text Available The paper wants to make a recall for the vet practitioners, of the main veterinary drug's metabolism rate influencing factors. Among the most important physiological factors (pharmacokinetics, sanguine flow and urinary ones, plasmatic proteins binding, enzymatic induction and inhibition are essential. Between the animal’s bounded factors more important are: species, individuality, age, sex, pregnancy, alimentation, genetic factors, and health status and from exogenous factors, daily rhythm, influences of chemical compounds and of the stress are presented.

Effects of Andrographis paniculata and Orthosiphon stamineus extracts on the glucuronidation of 4-methylumbelliferone in human UGT isoforms.

Science.gov (United States)

Ismail, Sabariah; Hanapi, Nur Aziah; Ab Halim, Mohd Rohaimi; Uchaipichat, Verawan; Mackenzie, Peter I

2010-05-14

The effects of Andrographis paniculata and Orthosiphon stamineus extracts on the in vitro glucuronidation of 4-methylumbelliferone (4MU) by recombinant human UGTs, UGT1A1, UGT1A3, UGT1A6, UGT1A7, UGT1A8, UGT1A10, UGT2B7 and UGT2B15 were determined. The potential inhibitory effects of both of the extracts on the activity of each of the UGT isoforms were investigated using 4MU as the substrate. Incubations contained UDP-glucuronic acid (UDPGA) as the cofactor, MgCl(2), cell lysate of respective isoform, and 4MU at the approximate apparent K(m) or S(50) value of each isoform. Final concentrations of Andrographis paniculata and Orthosiphon stamineus extracts used were 0.025, 0.25, 2.5, 25 and 50 microg/mL and 0.01, 0.10, 1.0, 10 and 50 microg/mL respectively. Both extracts variably inhibited the activity of most of the isoforms in a concentration dependent manner. Andrographis paniculata extract was the better inhibitor of all the isoforms studied (IC(50) 1.70 microg/mL for UGT1A3, 2.57 microg/mL for UGT1A8, 2.82 microg/mL for UGT2B7, 5.00 micorg/mL for UGT1A1, 5.66 microg/mL for UGT1A6, 9.88 microg/mL for UGT1A7 and 15.66 microg/mL for UGT1A10). Both extracts showed less than 70% inhibition of UGT2B15, so the IC(50) values were >50 microg/mL. The inhibition of human UGTs by Andrographis paniculata and Orthosiphon stamineus extracts in vitro suggests a potential for drug-herbal extract interactions in the therapeutic setting.

Risk Factors for Pancreatitis in Older Women: The Iowa Women’s Health Study

Science.gov (United States)

Prizment, Anna E.; Jensen, Eric H.; Hopper, Anne M; Virnig, Beth A.; Anderson, Kristin E.

2015-01-01

Purpose Pancreatitis – an inflammation of pancreas – is a severe and costly disease. While many risk factors for pancreatitis are known, many cases, especially in elderly, are of unknown etiology. Methods Risk factors for acute (AP) and chronic pancreatitis (CP) were assessed in a prospective cohort (n=36,436 women, aged ≥65 years). Exposures were self-reported at baseline. Pancreatitis was ascertained by linkage to Medicare claims (1986–2004) categorized by a physician as: “AP”, 1 AP episode (n=511); or “CP”, 2+ AP or 1+ CP episodes (n=149). Results Multivariable odds ratios (OR) and 95% CI for AP and CP were calculated using multinomial logistic regression. Alcohol use was not associated with AP or CP. Heavy smoking (40+ versus 0 pack-years) was associated with a 2-fold increased OR for CP. For BMI ≥30 versus <25 kg/m2, the ORs were 1.35 (1.07–1.70) for AP (p-trend=0.009) and 0.59 (0.37–0.94) for CP (p-trend=0.01). ORs for AP and CP were increased for HRT use, heart disease, and hypertension. There were positive significant associations between protein and total fat intake for CP and AP. Conclusions We identified factors associated with AP and CP that may be specific to older women. PMID:25656921

Synthesis of [¹¹C]PBR170, a novel imidazopyridine, for imaging the translocator protein with PET.

Science.gov (United States)

Bourdier, Thomas; Henderson, David; Fookes, Christopher J R; Lam, Peter; Mattner, Filomena; Fulham, Michael; Katsifis, Andrew

2014-08-01

The translocator protein (TSPO) ligand 2-(6,8-dichloro-2-(4-ethoxyphenyl)imidazo[1,2-a]pyridin-3-yl)-N-(2-fluoropyridin-3-yl)-N-methylacetamide (PBR170), is a novel imidazopyridineacetamide with high affinity (2.6 nm) and selectivity for the TSPO. The synthesis of [(11)C]PBR170 was accomplished by N-methylation of the corresponding desmethyl precursor with [(11)C]methyl iodide in the presence of sodium hydroxide in dimethylformamide. [(11)C]PBR170 was produced in 30-45% radiochemical yield (decay-corrected, based on [(11)C]methyl iodide) with a radiochemical purity >98% and a specific activity of 90-190 GBq/μmol after 35 min of synthesis time. Crown Copyright © 2014. Published by Elsevier Ltd. All rights reserved.

Di-4-octylphenylphosphoric acid as extractant : extraction of vanadium (IV) and beryllium

International Nuclear Information System (INIS)

Gajankush, R.B.

1976-01-01

The extraction of vanadium and beryllium has been studied using di-4-octylphenyl phosphoric acid (DOPPA) as metal extractant. The factors which affect the extraction have been studied in detail. An attempt has been made to clarify the mechanism of extraction and compare the results with those reported for di-2-ethylhexyl phosphoric acid (DEHPA). In the case of vanadium it was found that vanadium (IV) is more suitable for extraction. Synergistic extractionwas observed in the presence of neutral organophosphorous compounds like tri-n-butyl phosphate (TBP), dibutyl butyl phosphate (DBBP) and tri-n-octyl phosphine oxide (TOPO). The possibility of separating vanadium and uranium when they are present together in leach solutions has also been studied. The extraction of beryllium was found to be a slow process. The factors controlling the rate as well as the extent of extraction have been investigated. However, the results showed that in both respects DOPPA is better than DEHPA which was earlier studied by other authors. The separation of aluminium from beryllium has also been studied. (author)

Offline combination of pressurized fluid extraction and electron paramagnetic resonance spectroscopy for antioxidant activity of grape skin extracts assessment

Czech Academy of Sciences Publication Activity Database

Polovka, M.; Šťavíková, Lenka; Hohnová, Barbora; Karásek, Pavel; Roth, Michal

2010-01-01

Roč. 1217, č. 51 (2010), s. 7990-8000 ISSN 0021-9673 R&D Projects: GA ČR GA203/08/1536; GA MŠk LC06023 Institutional research plan: CEZ:AV0Z40310501 Keywords : pressurized fluid extraction * electron paramagnetic resonance spectroscopy * antioxidant activity Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 4.194, year: 2010

Natural moisturizing factors (NMF) in the stratum corneum (SC). I. Effects of lipid extraction and soaking.

Science.gov (United States)

Robinson, Marisa; Visscher, Marty; Laruffa, Angela; Wickett, Randy

2010-01-01

Natural moisturizing factor (NMF) is essential for appropriate stratum corneum hydration, barrier homeostasis, desquamation, and plasticity. It is formed from filaggrin proteolysis to small, hygroscopic molecules including amino acids. We hypothesized that common lipid extraction and soaking in water would alter the level of NMF in the upper SC and its biophysical properties. A novel method of measuring and quantifying the amino acid components of NMF is presented. Adhesive tapes were used to collect samples of the stratum corneum (SC) and were extracted with 6mM perchloric acid for analysis by reverse-phase HPLC. HPLC results were standardized to the amount of protein removed by the tapes. An increase in NMF was found with increased SC depth. Also, the combination of extraction and soaking was found to increase NMF loss relative to control or to extraction or soaking alone. Our results indicate that common skin care practices significantly influence the water binding materials in the upper SC. The findings have implications for the evaluation and formulation of skin care products.

43 CFR 46.170 - Environmental effects abroad of major Federal actions.

Science.gov (United States)

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Environmental effects abroad of major... IMPLEMENTATION OF THE NATIONAL ENVIRONMENTAL POLICY ACT OF 1969 Protection and Enhancement of Environmental Quality § 46.170 Environmental effects abroad of major Federal actions. (a) In order to facilitate...

Effect of plant extracts on Alzheimer′s disease: An insight into therapeutic avenues

Directory of Open Access Journals (Sweden)

M Obulesu

2011-01-01

Full Text Available Alzheimer′s disease (AD is a devastative neurodegenerative disorder which needs adequate studies on effective treatment options. The extracts of plants and their effect on the amelioration of AD symptoms have been extensively studied. This paper summarizes the mechanisms like acetylcholinesterase (AChE inhibition, modification of monoamines, antiamyloid aggregation effect, and antioxidant activity which are actively entailed in the process of amelioration of AD symptoms. These effects are induced by extracts of a few plants of different origin like Yizhi Jiannao, Moringa oleifera (Drumstick tree, Ginkgo Biloba (Ginkgo/Maidenhair tree, Cassia obtisufolia (Sicklepod, Desmodium gangeticum (Sal Leaved Desmodium, Melissa officinalis (Lemon Balm, and Salvia officinalis (Garden sage, common sage.

Gamow-Teller matrix elements from the C-12(d,He-2) and Mg-24(d,He-2) reactions at 170 MeV

NARCIS (Netherlands)

Baumer, C; Frekers, D; Schmidt, R; van den Berg, AM; Hannen, VM; Harakeh, MN; de Huu, MA; Wörtche, HJ; De Frenne, D; Hagemann, M; Heyse, J; Jacobs, E; Fujita, Y

The Mg-24(d,He-2)Na-24 and the C-12(d,He-2)B-12 charge-exchange reactions have been studied at an incident energy of 170 MeV. The two protons in the S-1(0)(pp) state (indicated as He-2) were both momentum analyzed and detected by the same spectrometer and detector. Background-free He-2 spectra with

Parameter extraction from I-V characteristics of PV devices

Energy Technology Data Exchange (ETDEWEB)

Macabebe, Erees Queen B. [Department of Electronics, Computer and Communications Engineering, Ateneo de Manila University, Loyola Heights, Quezon City 1108 (Philippines); Department of Physics and Centre for Energy Research, Nelson Mandela Metropolitan University, PO Box 77000, Port Elizabeth 6031 (South Africa); Sheppard, Charles J. [Department of Physics, University of Johannesburg, PO Box 524, Auckland Park 2006 (South Africa); Dyk, E. Ernest van [Department of Physics and Centre for Energy Research, Nelson Mandela Metropolitan University, PO Box 77000, Port Elizabeth 6031 (South Africa)

2011-01-15

Device parameters such as series and shunt resistances, saturation current and diode ideality factor influence the behaviour of the current-voltage (I-V) characteristics of solar cells and photovoltaic modules. It is necessary to determine these parameters since performance parameters are derived from the I-V curve and information provided by the device parameters are useful in analyzing performance losses. This contribution presents device parameters of CuIn(Se,S){sub 2}- and Cu(In,Ga)(Se,S){sub 2}-based solar cells, as well as, CuInSe{sub 2}, mono- and multicrystalline silicon modules determined using a parameter extraction routine that employs Particle Swarm Optimization. The device parameters of the CuIn(Se,S){sub 2}- and Cu(In,Ga)(Se,S){sub 2}-based solar cells show that the contribution of recombination mechanisms exhibited by high saturation current when coupled with the effects of parasitic resistances result in lower maximum power and conversion efficiency. Device parameters of photovoltaic modules extracted from I-V characteristics obtained at higher temperature show increased saturation current. The extracted values also reflect the adverse effect of temperature on parasitic resistances. The parameters extracted from I-V curves offer an understanding of the different mechanisms involved in the operation of the devices. The parameter extraction routine utilized in this study is a useful tool in determining the device parameters which reveal the mechanisms affecting device performance. (author)

Various Extraction Methods for Obtaining Stilbenes from Grape Cane of Vitis vinifera L

Czech Academy of Sciences Publication Activity Database

Soural, I.; Vrchotová, Naděžda; Tříska, Jan; Balík, J.; Horník, Štěpán; Cuřínová, Petra; Sýkora, Jan

2015-01-01

Roč. 20, č. 4 (2015), s. 6093-6112 ISSN 1420-3049 R&D Projects: GA MŠk(CZ) LD14038 Institutional support: RVO:67179843 ; RVO:67985858 Keywords : Vitis vinifera L * grape cane * stilbenes * accelerated solvent extraction ( ASE ) * microwave-assisted extraction (MAE) * LC-MS Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 2.465, year: 2015

45 CFR 170.465 - Revocation of authorized testing and certification body status.

Science.gov (United States)

2010-10-01

... INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.465 Revocation of authorized testing and certification body status. (a) Type-1...

Chemical Pleurodesis Using Doxycycline and Viscum album Extract

Directory of Open Access Journals (Sweden)

Kyung Sub Song

2017-08-01

Full Text Available Background: In chemical pleurodesis for managing pulmonary air leak, tetracycline derivatives are commonly used, and their effectiveness has been established in many studies. Recently, a Viscum album extract was used in chemical pleurodesis. We compared the effects of V. album with those of a tetracycline derivative (doxycycline to demonstrate the therapeutic effectiveness of the V. album extract in chemical pleurodesis for managing pulmonary air leak. Methods: Between October 2010 and October 2016, chemical pleurodesis was performed using doxycycline in 40 patients and the V. album extract in 37 patients. Thirty-three patients were in the postoperative state after pulmonary resection, and 44 patients suffered from spontaneous pneumothorax. Results: No statistically significant difference in the success rate was observed between the 2 groups (V. album e xtract a nd d oxycycline . In b oth groups, chest pain w as t he m ost common complication. More patients in the doxycycline group complained of severe chest pain (42.1% vs. 13.5%, p=0.006. In the V. album extract group, 24.3% of the patients required a chest tube to drain the pleural effusion after cessation of the air leak (doxycycline group: 5%, p=0.022. Further, the amount of pleural effusion drained on the day after the last chemical pleurodesis in the V. album extract group was greater than that in the doxycycline group (162.2±170.2 mL vs. 97.0±77.2 mL, p=0.032. All patients were discharged from the hospital without complications after pleural effusion drainage. Conclusion: Considering that treatment using the V. album extract was less painful, V. album might be a feasible option for chemical pleurodesis. However, pleural effusion should be monitored carefully when using V. album extract for treating patients suffering from air leak.

26 CFR 1.170-3 - Contributions or gifts by corporations (before amendment by Tax Reform Act of 1969).

Science.gov (United States)

2010-04-01

... Tax Reform Act of 1969). (a) In general. The deduction by a corporation in any taxable year for... 26 Internal Revenue 3 2010-04-01 2010-04-01 false Contributions or gifts by corporations (before amendment by Tax Reform Act of 1969). 1.170-3 Section 1.170-3 Internal Revenue INTERNAL REVENUE SERVICE...

[Decrease in N170 evoked potential component latency during repeated presentation of face images].

Science.gov (United States)

Verkhliutov, V M; Ushakov, V L; Strelets, V B

2009-01-01

The 15 healthy volunteers EEG from 28 channels was recorded during the presentation of visual stimuli in the form of face and building images. The stimuli were presented in two series. The first series consisted of 60 face and 60 building images presented in random order. The second series consisted of 30 face and 30 building images. The second series began 1.5-2 min after the end of the first ore. No instruction was given to the participants. P1, N170 and VPP EP components were identified for both stimuli categories. These components were located in the medial parietal area (Brodmann area 40). P1 and N170 components were recorded in the superior temporal fissure (Brodmann area 21, STS region), the first component had the latency 120 ms, the second one--155 ms. VPP was recorded with the latency 190 ms (Brodmann area 19). Dynamic mapping of EP components with the latency from 97 to 242 ms revealed the removal of positive maximums from occipital to frontal areas through temporal ones and their subsequent returning to occipital areas through the central ones. During the comparison of EP components to face and building images the amplitude differences were revealed in the following areas: P1--in frontal, central and anterior temporal areas, N170--in frontal, central, temporal and parietal areas, VPP--in all areas. It was also revealed that N170 latency was 12 ms shorter for face than for building images. It was proposed that the above mentioned N170 latency decrease for face in comparison with building images is connected with the different space location of the fusiform area responsible for face and building images recognition. Priming--the effect that is revealed during the repetitive face images presentation is interpreted as the manifestation of functional heterogeneity of the fusiform area responsible for the face images recognition. The hypothesis is put forward that the parts of extrastriate cortex which are located closer to the central retinotopical

Essays on the U.S. Housing Market and the Credit Market

OpenAIRE

Sun, Chuanlei

2012-01-01

This dissertation includes three chapters. The first two chapters focus on the U.S. housing market and the credit market and the third chapter emphasizes interest rate cycles and stock market cycles in the U.S.Chapter 2 proposes a dynamic factor model to study the U.S. housing market and the credit market separately in the last decades. The model extracts the latent unobserved state representing each market from an array of key related variables. The extracted factor from each market is compa...

25 CFR 170.933 - Can tribes regulate oversize or overweight vehicles?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Can tribes regulate oversize or overweight vehicles? 170... regulate oversize or overweight vehicles? Yes. Tribal governments can regulate travel on roads under their jurisdiction and establish a permitting process to regulate the travel of oversize or overweight vehicles, in...

In vitro antioxidant and anti-proliferative activity of Ethiopian medicinal plant extracts

Czech Academy of Sciences Publication Activity Database

Tauchen, J.; Doskočil, I.; Caffi, C.; Lulekal, E.; Maršík, Petr; Havlík, J.; Van Damme, P.; Kokoška, L.

2015-01-01

Roč. 74, NOV 15 (2015), s. 671-679 ISSN 0926-6690 Institutional support: RVO:61389030 Keywords : Antioxidant * Anticarcinogenic * Plant extract Subject RIV: GM - Food Processing Impact factor: 3.449, year: 2015

Distribution of ametropia in 1 170 preschool children with low vision

Directory of Open Access Journals (Sweden)

Li-Li Sun

2016-03-01

Full Text Available AIM:To observe and study the distribution of ametropia in 1 170 preschool children with low vision.METHODS:Ten kindergartens in the urban area of Jinzhou were randomly selected. For the preschool children aged from 3 to 6, the vision conditions including sight test, ocular inspection, refraction status, conventional ophthalmic testing and stereo tests were conducted. The children with visionRESULTS:(1rates of abnormal vision were 6.37% in children aged 3,7.79% in those aged 4,15.24% in those aged 5 and 8.93% in those aged 6; abnormal rate in children aged 5 was significantly higher than those in the other age groups(PCONCLUSION:For preschool children with low vision, the abnormal rate is reduced with the increasing ages since the vision is gradually mature. Based on the results, hyperopia is the main causes for low vision in preschool children(aged from 3 to 6. Based on the factors of myopia, strabismus and amblyopia, it is important to conduct the general survey in curing eye diseases as early as possible.

Factors influencing women\\'s decisions to purchase specific children ...

African Journals Online (AJOL)

Factors influencing women\\'s decisions to purchase specific children\\'s ... they had selected a children's multi-nutrient supplement with the intention of buying it. ... Price, performance and brand loyalty, affect and normative factors were most ...

Inner bremsstrahlung accompanying β-decay of 170Tm

International Nuclear Information System (INIS)

Gundu Rao, K.S.; Venkataramaiah, P.; Gopala, K.; Sanjeeviah, H.

1981-01-01

Inner bremsstrahlung accompanying non-unique first-forbidden β-decay of 170 Tm has been measured employing a magnetic deflection technique with a (4.5 x 5.1 cm) NaI(Tl) scintillation spectrometer in the energy region 200 keV to 900 keV. The raw spectrum is unfolded using the Liden and Starfelt procedure, and compared with the theories of KUB, Lewis and Ford, and Ford and Martin. The results are close to the Lewis and Ford theory over the major portion of the measured spectrum. (orig.)

Enhanced biocompatibility of ZnS:Mn quantum dots encapsulated with Aloe vera extract for therapeutic applications

Science.gov (United States)

Anilkumar, M.; Bindu, K. R.; Sneha Saj, A.; Anila, E. I.

2016-08-01

Toxicity of nanoparticles remains to be a major issue in their application to the biomedical field. Aloe vera (AV) is one of the most widely exploited medicinal plants that have a multitude of amazing properties in the field of medicine. Methanol extract of Aloe vera can be used as a novel stabilising agent for quantum dots to reduce toxicity. We report the synthesis, structural characterization, antibacterial activity and cytotoxicity studies of ZnS:Mn quantum dots synthesized by the colloidal precipitation method, using methanol extract of Aloe vera (AVME) as the capping agent. The ZnS:Mn quantum dots capped with AVME exhibit superior performances in biocompatibility and antibacterial activity compared with ZnS:Mn quantum dots without encapsulation. Project supported by the Science and Engineering Research Board (SERB), Department of Science and Technology (DST), Government of India.

Improved External Base Resistance Extraction for Submicrometer InP/InGaAs DHBT Models

DEFF Research Database (Denmark)

Johansen, Tom Keinicke; Krozer, Viktor; Nodjiadjim, Virginie

2011-01-01

An improved direct parameter extraction method is proposed for III–V heterojunction bipolar transistor (HBT) external base resistance $R_{\\rm bx}$ extraction from forward active $S$-parameters. The method is formulated taking into account the current dependence of the intrinsic base–collector cap......An improved direct parameter extraction method is proposed for III–V heterojunction bipolar transistor (HBT) external base resistance $R_{\\rm bx}$ extraction from forward active $S$-parameters. The method is formulated taking into account the current dependence of the intrinsic base...... factor given as the ratio of the emitter to the collector area. The determination of the parameters $I_{p}$ and $X_{0}$ from experimental $S$-parameters is described. The method is applied to high-speed submicrometer InP/InGaAs DHBT devices and leads to small-signal equivalent circuit models, which...

Solid-Liquid Extraction Kinetics of Total Phenolic Compounds (TPC from Red Dates

Directory of Open Access Journals (Sweden)

Bee Lin Chua

2018-01-01

Full Text Available Red dates are one of the most famous herbal plants in making traditional Chinese medicine. They contain large amount of bioactive compounds. The objectives of this research were to optimise the crude extract yield and total phenolic compounds (TPC yield from red dates using response surface methodology (RSM and model the extraction kinetics of TPC yield from red dates. Date fruits were dried in an oven under temperatures 50°C, 60°C, 70°C and 80°C until a constant weight was obtained. The optimum drying temperature was 60°C as it gave the highest crude extract yield and TPC yield. Besides that, single factor experiments were used to determine the optimum range of four extraction parameters which were: liquid-solid ratio (10-30 ml/g; ultrasonic power (70-90%; extraction temperature (50-70°C; and extraction time (40-60min. The optimum range of the four parameters were further optimised using the Box-Behken Design (BBD of RSM. The extraction conditions that gave the highest crude extract yield and TPC yield were chosen. The optimum value for liquid-solid ratio, ultrasonic power, extraction temperature and extraction time were 30ml/g, 70%, 60°C and 60 min respectively. The two equations generated from RSM were reliable and can be used to predict the crude extract yield and TPC yield. The higher the extraction temperature, liquid-solid ratio, and extraction time and lower ultrasonic power, the higher the crude extract and TPC yield. Finally, the results of TPC yield versus time based on the optimum extraction parameters from RSM optimisation were fitted into three extraction kinetic models (Peleg’s model, Page’s model and Ponomaryov’s model. It was found that the most suitable kinetic model to represent the extraction process of TPC from red dates was Page’s model due to its coefficient of determination (R2 was the closest to unity, 0.9663 while its root mean square error (RMSE was the closest to zero, 0.001534.

25 CFR 170.925 - Is ERFO funding supplemental to IRR Program funding?

Science.gov (United States)

2010-04-01

... RESERVATION ROADS PROGRAM Miscellaneous Provisions Emergency Relief § 170.925 Is ERFO funding supplemental to... construction and maintenance funds for FHWA-approved repairs. If IRR construction or maintenance funds are used... used to reimburse the construction or maintenance funds expended. ...

7 CFR 170.9 - What type of information does the application require?

Science.gov (United States)

2010-01-01

... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) MISCELLANEOUS MARKETING PRACTICES UNDER THE AGRICULTURAL MARKETING ACT OF 1946 USDA FARMERS MARKET § 170.9 What... Market will provide market management with information on contacts, farm location, type of farming...

46 CFR 7.170 - Alaska Peninsula, AK to Aleutian Islands, AK.

Science.gov (United States)

2010-10-01

... BOUNDARY LINES Alaska § 7.170 Alaska Peninsula, AK to Aleutian Islands, AK. (a) A line drawn from the southernmost extremity of Cape Kumlium to the westernmost extremity of Nakchamik Island; thence to the... Light at Iliuliuk Bay entrance. (c) A line drawn from Arch Rock to the northernmost extremity of...

Direct analysis of free aqueous and organic operational solutions as a tool for understanding fundamental principles of electromembrane extraction

Czech Academy of Sciences Publication Activity Database

Šlampová, Andrea; Kubáň, Pavel

2017-01-01

Roč. 89, č. 23 (2017), s. 12960-12967 ISSN 0003-2700 R&D Projects: GA ČR(CZ) GA16-09135S Institutional support: RVO:68081715 Keywords : basic drugs * capillary electrophoresis * electromembrane extraction * extraction kinetics Subject RIV: CB - Analytical Chemistry, Separation OBOR OECD: Analytical chemistry Impact factor: 6.320, year: 2016

Direct analysis of free aqueous and organic operational solutions as a tool for understanding fundamental principles of electromembrane extraction

Czech Academy of Sciences Publication Activity Database

Šlampová, Andrea; Kubáň, Pavel

2017-01-01

Roč. 89, č. 23 (2017), s. 12960-12967 ISSN 0003-2700 R&D Projects: GA ČR(CZ) GA16-09135S Institutional support: RVO:68081715 Keywords : basic drugs * capillary electrophoresis * electromembrane extraction * extraction kinetics Subject RIV: CB - Analytical Chemistry , Separation OBOR OECD: Analytical chemistry Impact factor: 6.320, year: 2016

Effects of onion extract on endogenous vascular H2S and adrenomedulin in rat atherosclerosis.

Science.gov (United States)

Li, Wei; Tang, Chaoshu; Jin, Hongfang; Du, Junbao

2011-09-01

This study aimed to explore the effect of onion extract on endogenous hydrogen sulfide (H2S) and adrenomedulin (ADM) and on atherosclerotic progression in rats with atherosclerosis (AS). Male Sprague-Dawley rats were randomly divided into control, AS and AS+onion groups. Ultrastructure of aorta and atherosclerotic lesions both in aorta and in coronary artery were detected. Plasma and aortic H2S were detected by using a sulfide- sensitive electrode. Plasma and aortic ADM was determined with radioimmunoassay. Cystathionine-γ-lyase (CSE), calcitonin receptor-like receptor (CRLR), receptor activity-modifying protein (RAMP1, RAMP2 and RAMP3) mRNA expressions were analysed. Glutathione peroxidase (GSH-PX), superoxide dismutase (SOD), malondialdehyde (MDA), nitric oxide (NO) and NO synthase (NOS) contents in plasma, SOD1, SOD2 and ICAM-1 expressions in aorta were detected. Rats in the AS group showed marked atherosclerotic lesions both in aorta and in coronary artery but decreased aortic H2S production. Decreased plasma and aortic ADM content, but increased levels of aortic CRLR, RAMP2 and RAMP3 mRNAs were observed. Plasma GSH-PX and SOD were reduced but MDA elevated. Plasma ICAM-1 and NO contents and iNOS activity were increased. Onion extract, however, lessened atherosclerotic lesions and increased endogenous aortic H2S production, but decreased plasma ADM content, aortic ADM content and aortic CRLR, RAMP2 and RAMP3 mRNAs. In addition, it increased plasma GSH-PX level and SOD activities but reduced MDA; it decreased inflammatory response but increased plasma eNOS activity and NO content. Onion extract exerted a marked antiatherogenic effect in association with the up-regulation of the endogenous CSE/H2S pathway but down-regulation of the ADM/CRLR family in atherosclerotic rats.

Search for the standard model Higgs boson in $e^+ e^-$ collisions at $\\sqrt{s}$=161, 170 and 172 GeV

CERN Document Server

Barate, R; Décamp, D; Ghez, P; Goy, C; Lees, J P; Lucotte, A; Minard, M N; Nief, J Y; Pietrzyk, B; Casado, M P; Chmeissani, M; Comas, P; Crespo, J M; Delfino, M C; Fernández, E; Fernández-Bosman, M; Garrido, L; Juste, A; Martínez, M; Merino, G; Miquel, R; Mir, L M; Padilla, C; Park, I C; Pascual, A; Perlas, J A; Riu, I; Sánchez, F; Teubert, F; Colaleo, A; Creanza, D; De Palma, M; Gelao, G; Iaselli, Giuseppe; Maggi, G; Maggi, M; Marinelli, N; Nuzzo, S; Ranieri, A; Raso, G; Ruggieri, F; Selvaggi, G; Silvestris, L; Tempesta, P; Tricomi, A; Zito, G; Huang, X; Lin, J; Ouyang, Q; Wang, T; Xie, Y; Xu, R; Xue, S; Zhang, J; Zhang, L; Zhao, W; Abbaneo, D; Alemany, R; Bazarko, A O; Becker, U; Bright-Thomas, P G; Cattaneo, M; Cerutti, F; Dissertori, G; Drevermann, H; Forty, Roger W; Frank, M; Hagelberg, R; Hansen, J B; Harvey, J; Janot, P; Jost, B; Kneringer, E; Knobloch, J; Lehraus, Ivan; Lutters, G; Mato, P; Minten, Adolf G; Moneta, L; Pacheco, A; Pusztaszeri, J F; Ranjard, F; Rizzo, G; Rolandi, Luigi; Rousseau, D; Schlatter, W D; Schmitt, M; Schneider, O; Tejessy, W; Tomalin, I R; Wachsmuth, H W; Wagner, A; Ajaltouni, Ziad J; Barrès, A; Boyer, C; Falvard, A; Ferdi, C; Gay, P; Guicheney, C; Henrard, P; Jousset, J; Michel, B; Monteil, S; Montret, J C; Pallin, D; Perret, P; Podlyski, F; Proriol, J; Rosnet, P; Rossignol, J M; Fearnley, Tom; Hansen, J D; Hansen, J R; Hansen, P H; Nilsson, B S; Rensch, B; Wäänänen, A; Daskalakis, G; Kyriakis, A; Markou, C; Simopoulou, Errietta; Vayaki, Anna; Blondel, A; Brient, J C; Machefert, F P; Rougé, A; Rumpf, M; Valassi, Andrea; Videau, H L; Focardi, E; Parrini, G; Zachariadou, K; Cavanaugh, R J; Corden, M; Georgiopoulos, C H; Hühn, T; Jaffe, D E; Antonelli, A; Bencivenni, G; Bologna, G; Bossi, F; Campana, P; Capon, G; Casper, David William; Chiarella, V; Felici, G; Laurelli, P; Mannocchi, G; Murtas, F; Murtas, G P; Passalacqua, L; Pepé-Altarelli, M; Curtis, L; Dorris, S J; Halley, A W; Knowles, I G; Lynch, J G; O'Shea, V; Raine, C; Scarr, J M; Smith, K; Teixeira-Dias, P; Thompson, A S; Thomson, E; Thomson, F; Turnbull, R M; Buchmüller, O L; Dhamotharan, S; Geweniger, C; Graefe, G; Hanke, P; Hansper, G; Hepp, V; Kluge, E E; Putzer, A; Sommer, J; Tittel, K; Werner, S; Wunsch, M; Beuselinck, R; Binnie, David M; Cameron, W; Dornan, Peter J; Girone, M; Goodsir, S M; Martin, E B; Morawitz, P; Moutoussi, A; Nash, J; Sedgbeer, J K; Spagnolo, P; Stacey, A M; Williams, M D; Ghete, V M; Girtler, P; Kuhn, D; Rudolph, G; Betteridge, A P; Bowdery, C K; Colrain, P; Crawford, G; Finch, A J; Foster, F; Hughes, G; Jones, R W L; Sloan, Terence; Whelan, E P; Williams, M I; Hoffmann, C; Jakobs, K; Kleinknecht, K; Quast, G; Renk, B; Rohne, E; Sander, H G; Van Gemmeren, P; Zeitnitz, C; Aubert, Jean-Jacques; Benchouk, C; Bonissent, A; Bujosa, G; Carr, J; Coyle, P; Diaconu, C A; Ealet, A; Fouchez, D; Konstantinidis, N P; Leroy, O; Motsch, F; Payre, P; Talby, M; Sadouki, A; Thulasidas, M; Tilquin, A; Trabelsi, K; Aleppo, M; Antonelli, M; Ragusa, F; Berlich, R; Blum, Walter; Büscher, V; Dietl, H; Ganis, G; Gotzhein, C; Kroha, H; Lütjens, G; Lutz, Gerhard; Männer, W; Moser, H G; Richter, R H; Rosado-Schlosser, A; Schael, S; Settles, Ronald; Seywerd, H C J; Saint-Denis, R; Stenzel, H; Wiedenmann, W; Wolf, G; Boucrot, J; Callot, O; Chen, S; Cordier, A; Davier, M; Duflot, L; Grivaz, J F; Heusse, P; Höcker, A; Jacholkowska, A; Jacquet, M; Kado, M; Kim, D W; Le Diberder, F R; Lefrançois, J; Lutz, A M; Nikolic, I A; Schune, M H; Serin, L; Simion, S; Tournefier, E; Veillet, J J; Videau, I; Zerwas, D; Azzurri, P; Bagliesi, G; Bettarini, S; Bozzi, C; Calderini, G; Ciulli, V; Dell'Orso, R; Fantechi, R; Ferrante, I; Giassi, A; Gregorio, A; Ligabue, F; Lusiani, A; Marrocchesi, P S; Messineo, A; Palla, Fabrizio; Sanguinetti, G; Sciabà, A; Steinberger, Jack; Tenchini, Roberto; Vannini, C; Venturi, A; Verdini, P G; Blair, G A; Bryant, L M; Chambers, J T; Gao, Y; Green, M G; Medcalf, T; Perrodo, P; Strong, J A; Von Wimmersperg-Töller, J H; Botterill, David R; Clifft, R W; Edgecock, T R; Haywood, S; Maley, P; Norton, P R; Thompson, J C; Wright, A E; Bloch-Devaux, B; Colas, P; Fabbro, B; Kozanecki, Witold; Lançon, E; Lemaire, M C; Locci, E; Pérez, P; Rander, J; Renardy, J F; Rosowsky, A; Roussarie, A; Schuller, J P; Schwindling, J; Trabelsi, A; Vallage, B; Black, S N; Dann, J H; Kim, H Y; Litke, A M; McNeil, M A; Taylor, G; Booth, C N; Boswell, R; Brew, C A J; Cartwright, S L; Combley, F; Kelly, M S; Lehto, M H; Newton, W M; Reeve, J; Thompson, L F; Affholderbach, K; Böhrer, A; Brandt, S; Cowan, G D; Foss, J; Grupen, Claus; Saraiva, P; Smolik, L; Stephan, F; Apollonio, M; Bosisio, L; Della Marina, R; Giannini, G; Gobbo, B; Musolino, G; Pütz, J; Rothberg, J E; Wasserbaech, S R; Williams, R W; Armstrong, S R; Charles, E; Elmer, P; Ferguson, D P S; González, S; Greening, T C; Hayes, O J; Hu, H; Jin, S; McNamara, P A; Nachtman, J M; Nielsen, J; Orejudos, W; Pan, Y B; Saadi, Y; Scott, I J; Walsh, J; Wu Sau Lan; Wu, X; Yamartino, J M; Zobernig, G

1997-01-01

The reaction e+e- -> HZ is used to search for the Standard Model Higgs boson. The data sample consists of integrated luminosities of 10.9pb-1 1.1pb-1 and 9.5pb-1 collected by the ALEPH experiment at LEP during 1996, at centre-of-mass energies of 161, 170 and 172GeV, respectively. No candidate events were found, in agreement with the expected background of 0.84 events from all Standard Model processes. This search results in a 95%C.L. lower limit on the Higgs boson mass of 69.4GeV. When combined with earlier ALEPH searches performed at energies at and around the Z peak, this limit increases to 70.7GeV

Search for the Standard Model Higgs boson in e+e- collisions at sqrt(s)=161, 170 and 172GeV

Science.gov (United States)

ALEPH Collaboration; Barate, R.; Buskulic, D.; Decamp, D.; Ghez, P.; Goy, C.; Lees, J.-P.; Lucotte, A.; Minard, M.-N.; Nief, J.-Y.; Pietrzyk, B.; Casado, M. P.; Chmeissani, M.; Comas, P.; Crespo, J. M.; Delfino,, M.; Fernandez, E.; Fernandez-Bosman, M.; Garrido, Ll.; Juste, A.; Martinez, M.; Merino, G.; Miquel, R.; Mir, Ll. M.; Padilla, C.; Park, I. C.; Pascual, A.; Perlas, J. A.; Riu, I.; Sanchez, F.; Teubert, F.; Colaleo, A.; Creanza, D.; de Palma, M.; Gelao, G.; Iaselli, G.; Maggi, G.; Maggi, M.; Marinelli, N.; Nuzzo, S.; Ranieri, A.; Raso, G.; Ruggieri, F.; Selvaggi, G.; Silvestris, L.; Tempesta, P.; Tricomi, A.; Zito, G.; Huang, X.; Lin, J.; Ouyang, Q.; Wang, T.; Xie, Y.; Xu, R.; Xue, S.; Zhang, J.; Zhang, L.; Zhao, W.; Abbaneo, D.; Alemany, R.; Bazarko, A. O.; Becker, U.; Bright-Thomas, P.; Cattaneo, M.; Cerutti, F.; Dissertori, G.; Drevermann, H.; Forty, R. W.; Frank, M.; Hagelberg, R.; Hansen, J. B.; Harvey, J.; Janot, P.; Jost, B.; Kneringer, E.; Knobloch, J.; Lehraus, I.; Lutters, G.; Mato, P.; Minten, A.; Moneta, L.; Pacheco, A.; Pusztaszeri, J.-F.; Ranjard, F.; Rizzo, G.; Rolandi, L.; Rousseau, D.; Schlatter, D.; Schmitt, M.; Schneider, O.; Tejessy, W.; Tomalin, I. R.; Wachsmuth, H.; Wagner, A.; Ajaltouni, Z.; Barrès, A.; Boyer, C.; Falvard, A.; Ferdi, C.; Gay, P.; Guicheney, C.; Henrard, P.; Jousset, J.; Michel, B.; Monteil, S.; Montret, J.-C.; Pallin, D.; Perret, P.; Podlyski, F.; Proriol, J.; Rosnet, P.; Rossignol, J.-M.; Fearnley, T.; Hansen, J. D.; Hansen, J. R.; Hansen, P. H.; Nilsson, B. S.; Rensch, B.; Wäänänen, A.; Daskalakis, G.; Kyriakis, A.; Markou, C.; Simopoulou, E.; Vayaki, A.; Blondel, A.; Brient, J. C.; Machefert, F.; Rougé, A.; Rumpf, M.; Valassi, A.; Videau, H.; Focardi, E.; Parrini, G.; Zachariadou, K.; Cavanaugh, R.; Corden, M.; Georgiopoulos, C.; Huehn, T.; Jaffe, D. E.; Antonelli, A.; Bencivenni, G.; Bologna, G.; Bossi, F.; Campana, P.; Capon, G.; Casper, D.; Chiarella, V.; Felici, G.; Laurelli, P.; Mannocchi, G.; Murtas, F.; Murtas, G. P.; Passalacqua, L.; Pepe-Altarelli, M.; Curtis, L.; Dorris, S. J.; Halley, A. W.; Knowles, I. G.; Lynch, J. G.; O'Shea, V.; Raine, C.; Scarr, J. M.; Smith, K.; Teixeira-Dias, P.; Thompson, A. S.; Thomson, E.; Thomson, F.; Turnbull, R. M.; Buchmüller, O.; Dhamotharan, S.; Geweniger, C.; Graefe, G.; Hanke, P.; Hansper, G.; Hepp, V.; Kluge, E. E.; Putzer, A.; Sommer, J.; Tittel, K.; Werner, S.; Wunsch, M.; Beuselinck, R.; Binnie, D. M.; Cameron, W.; Dornan, P. J.; Girone, M.; Goodsir, S.; Martin, E. B.; Morawitz, P.; Moutoussi, A.; Nash, J.; Sedgbeer, J. K.; Spagnolo, P.; Stacey, A. M.; Williams, M. D.; Ghete, V. M.; Girtler, P.; Kuhn, D.; Rudolph, G.; Betteridge, A. P.; Bowdery, C. K.; Colrain, P.; Crawford, G.; Finch, A. J.; Foster, F.; Hughes, G.; Jones, R. W.; Sloan, T.; Whelan, E. P.; Williams, M. I.; Hoffmann, C.; Jakobs, K.; Kleinknecht, K.; Quast, G.; Renk, B.; Rohne, E.; Sander, H.-G.; van Gemmeren, P.; Zeitnitz, C.; Aubert, J. J.; Benchouk, C.; Bonissent, A.; Bujosa, G.; Carr, J.; Coyle, P.; Diaconu, C.; Ealet, A.; Fouchez, D.; Konstantinidis, N.; Leroy, O.; Motsch, F.; Payre, P.; Talby, M.; Sadouki, A.; Thulasidas, M.; Tilquin, A.; Trabelsi, K.; Aleppo, M.; Antonelli, M.; Ragusa, F.; Berlich, R.; Blum, W.; Büscher, V.; Dietl, H.; Ganis, G.; Gotzhein, C.; Kroha, H.; Lütjens, G.; Lutz, G.; Männer, W.; Moser, H.-G.; Richter, R.; Rosado-Schlosser, A.; Schael, S.; Settles, R.; Seywerd, H.; St. Denis, R.; Stenzel, H.; Wiedenmann, W.; Wolf, G.; Boucrot, J.; Callot, O.; Chen, S.; Cordier, A.; Davier, M.; Duflot, L.; Grivaz, J.-F.; Heusse, Ph.; Höcker, A.; Jacholkowska, A.; Jacquet, M.; Kado, M.; Kim, D. W.; Le Diberder, F.; Lefrançois, J.; Lutz, A.-M.; Nikolic, I.; Schune, M.-H.; Serin, L.; Simion, S.; Tournefier, E.; Veillet, J.-J.; Videau, I.; Zerwas, D.; Azzurri, P.; Bagliesi, G.; Bettarini, S.; Bozzi, C.; Calderini, G.; Ciulli, V.; dell'Orso, R.; Fantechi, R.; Ferrante, I.; Giassi, A.; Gregorio, A.; Ligabue, F.; Lusiani, A.; Marrocchesi, P. S.; Messineo, A.; Palla, F.; Sanguinetti, G.; Sciabà, A.; Steinberger, J.; Tenchini, R.; Vannini, C.; Venturi, A.; Verdini, P. G.; Blair, G. A.; Bryant, L. M.; Chambers, J. T.; Gao, Y.; Green, M. G.; Medcalf, T.; Perrodo, P.; Strong, J. A.; von Wimmersperg-Toeller, J. H.; Botterill, D. R.; Clifft, R. W.; Edgecock, T. R.; Haywood, S.; Maley, P.; Norton, P. R.; Thompson, J. C.; Wright, A. E.; Bloch-Devaux, B.; Colas, P.; Fabbro, B.; Kozanecki, W.; Lançon, E.; Lemaire, M. C.; Locci, E.; Perez, P.; Rander, J.; Renardy, J.-F.; Rosowsky, A.; Roussarie, A.; Schuller, J.-P.; Schwindling, J.; Trabelsi, A.; Vallage, B.; Black, S. N.; Dann, J. H.; Kim, H. Y.; Litke, A. M.; McNeil, M. A.; Taylor, G.; Booth, C. N.; Boswell, R.; Brew, C. A. J.; Cartwright, S.; Combley, F.; Kelly, M. S.; Lehto, M.; Newton, W. M.; Reeve, J.; Thompson, L. F.; Affholderbach, K.; Böhrer, A.; Brandt, S.; Cowan, G.; Foss, J.; Grupen, C.; Saraiva, P.; Smolik, L.; Stephan, F.; Apollonio, M.; Bosisio, L.; della Marina, R.; Giannini, G.; Gobbo, B.; Musolino, G.; Putz, J.; Rothberg, J.; Wasserbaech, S.; Williams, R. W.; Armstrong, S. R.; Charles, E.; Elmer, P.; Ferguson, D. P. S.; González, S.; Greening, T. C.; Hayes, O. J.; Hu, H.; Jin, S.; McNamara, P. A., III; Nachtman, J. M.; Nielsen, J.; Orejudos, W.; Pan, Y. B.; Saadi, Y.; Scott, I. J.; Walsh, J.; Wu, Sau Lan; Wu, X.; Yamartino, J. M.; Zobernig, G.

1997-10-01

The reaction e+e--->HZ is used to search for the Standard Model Higgs boson. The data sample consists of integrated luminosities of 10.9pb-1, 1.1pb-1, and 9.5pb-1 collected by the ALEPH experiment at LEP during 1996, at centre-of-mass energies of 161, 170 and 172GeV, respectively. No candidate events were found, in agreement with the expected background of 0.84 events from all Standard Model processes. This search results in a 95% C.L. lower limit on the Higgs boson mass of 69.4GeV/c2. When combined with earlier ALEPH searches performed at energies at and around the Z peak, this limit increases to 70.7GeV/c2.

Asp170 is crucial for the redox properties of vanillyl-alcohol oxidase

NARCIS (Netherlands)

Heuvel, van den R.H.H.; Fraaije, M.W.; Mattevi, A.; Berkel, van W.J.H.

2000-01-01

Vanillyl-alcohol oxidase is a flavoprotein containing a covalent flavin that catalyzes the oxidation of 4-(methoxymethyl)phenol to 4-hydroxybenzaldehyde. The reaction proceeds through the formation of a p-quinone methide intermediate, after which, water addition takes place. Asp-170, located near

Asp-170 Is Crucial for the Redox Properties of Vanillyl-alcohol Oxidase

NARCIS (Netherlands)

Heuvel, Robert H.H. van den; Fraaije, Marco W.; Mattevi, Andrea; Berkel, Willem J.H. van

2000-01-01

Vanillyl-alcohol oxidase is a flavoprotein containing a covalent flavin that catalyzes the oxidation of 4-(methoxymethyl)phenol to 4-hydroxybenzaldehyde. The reaction proceeds through the formation of a p-quinone methide intermediate, after which, water addition takes place. Asp-170, located near

CMP(O) tripodands: synthesis, potentiometric studies and extractions

Czech Academy of Sciences Publication Activity Database

Reinoso-García, M.M.; Janczewski, D.; Reinhoudt, D.N.; Verboom, W.; Malinowska, E.; Pietrzak, M.; Hill, C.; Báča, Jiří; Grüner, Bohumír; Selucký, P.; Grűttner, C.

2006-01-01

Roč. 30, č. 10 (2006), s. 1480-1492 ISSN 1144-0546 Grant - others:EEC(PL) FIKW-CT-2000-00088; EEC(PL) F16W-CT-2003-508854 Institutional research plan: CEZ:AV0Z40320502 Keywords : assisted chemical-separation * complex-formation constants * solvent-extraction Subject RIV: CA - Inorganic Chemistry Impact factor: 2.647, year: 2006

Supercritical CO2 Extraction of Salvia officinalis L

Czech Academy of Sciences Publication Activity Database

Aleksovski, S.A.; Sovová, Helena

2007-01-01

Roč. 40, č. 2 (2007), s. 239-245 ISSN 0896-8446 R&D Projects: GA AV ČR(CZ) IAA4072102 Grant - others:GA_(MK) 40108601/0 Institutional research plan: CEZ:AV0Z40720504 Keywords : supercritical fluid extraction * essential oil * collection efficiency Subject RIV: CI - Industrial Chemistry, Chemical Engineering Impact factor: 2.189, year: 2007

Factors influencing phase-disengagement rates in solvent-extraction systems employing tertiary amine extractants

International Nuclear Information System (INIS)

Moyer, B.A.; McDowell, W.J.

1981-01-01

The primary purpose of the present investigation was to examine the effects of amine size and structure on phase disengagement. Nine commercial tertiary amines were tested together with four laboratory-quality amines for uranium extraction and both organic-continuous (OC) and aqueous-continuous (AC) phase disengagement under Amex-type conditions. Synthetic acid sulfate solutions with and without added colloidal silica and actual ore leach solutions were used as the aqueous phases. Phase disengagement results were correlated with amine size and branching and solution wetting behavior on a silicate (glass) surface. The results suggest that the performance of some Amex systems may be improved by using branched chain tertiary amine extractants of higher molecular weight than are now normally used

Exploratory factor analysis in Rehabilitation Psychology: a content analysis.

Science.gov (United States)

Roberson, Richard B; Elliott, Timothy R; Chang, Jessica E; Hill, Jessica N

2014-11-01

Our objective was to examine the use and quality of exploratory factor analysis (EFA) in articles published in Rehabilitation Psychology. Trained raters examined 66 separate exploratory factor analyses in 47 articles published between 1999 and April 2014. The raters recorded the aim of the EFAs, the distributional statistics, sample size, factor retention method(s), extraction and rotation method(s), and whether the pattern coefficients, structure coefficients, and the matrix of association were reported. The primary use of the EFAs was scale development, but the most widely used extraction and rotation method was principle component analysis, with varimax rotation. When determining how many factors to retain, multiple methods (e.g., scree plot, parallel analysis) were used most often. Many articles did not report enough information to allow for the duplication of their results. EFA relies on authors' choices (e.g., factor retention rules extraction, rotation methods), and few articles adhered to all of the best practices. The current findings are compared to other empirical investigations into the use of EFA in published research. Recommendations for improving EFA reporting practices in rehabilitation psychology research are provided.

New approach for extraction of cellulose from tucumã's endocarp and its structural characterization

Science.gov (United States)

Manzato, L.; Rabelo, L. C. A.; de Souza, S. M.; da Silva, C. G.; Sanches, E. A.; Rabelo, D.; Mariuba, L. A. M.; Simonsen, J.

2017-09-01

The recycling of plant wasted materials into useful products represents a green alternative to prevent environmental problems. Tucumã palm fruit (Astrocaryum aculeatum Meyer) is widely used in Amazon region for food and crafts. Due to the large amount of wasted Tucumã's endocarp, this work proposes a new approach for extraction of cellulose and its structural characterization. X-ray Diffraction (XRD), Rietveld Refinement, Scanning Electron Microscopy (SEM), Infrared-transform Fourier Spectroscopy (FTIR) and Thermal Analysis (TG/DSC) have been used for characterization of the extracted cellulose. XRD patterns of the in natura tucumã's endocarp has showed a natural crystalline content embedded in a non-crystalline matrix. Nanocrystals of cellulose have been observed in the XRD pattern of the extracted cellulose, showing a good agreement with type II. Rietveld refinement allowed the cell parameters obtainment (a = 8.43(1) Å, b = 9.50(1) Å, c = 9.39(3) Å and γ = 118.43(4)°). Apparent average crystallite size and microstrain were, respectively, 20.0 Å and 0.1%. Two different methods were applied for estimative of crystallinity percentage. In the first method the height ratio between the intensity of the crystalline peak and the total intensity after the subtraction of the non-crystalline content was applied, leading to 48.5%. The second approach was performed using the amorphous area and the total area of the (1 1 0) peak from the experimental diffractogram, leading to 31.5%. The difference in crystallinity percentage concerning these two used approaches may be explained due to the first method does not consider the broad peaks resulted from nanocrystals diffraction. FTIR spectroscopy has evidenced a cellulose type II structure. SEM images showed micrometric sized fibers with ranged thicknesses. However, a new morphology of spherical nanostructures was observed on the type II matrix fibers. Thermal analysis suggests that the extracted cellulose have low thermal

Sphingomyelinase Activity of Trichomonas vaginalis Extract and Subfractions

Directory of Open Access Journals (Sweden)

Francisco González-Salazar

2013-01-01

Full Text Available Trichomoniasis is one of the most common acute sexually transmitted curable diseases, and it is disseminated worldwide generating more than 170 million cases annually. Trichomonas vaginalis is the parasite that causes trichomoniasis and has the ability to destroy cell monolayers of the vaginal mucosa in vitro. Sphingomyelinases (SMase are enzymes that catalyze the hydrolysis of sphingomyelin into ceramide and phosphorylcholine. Ceramide appears to be a second messenger lipid in programmed apoptosis, cell differentiation, and cell proliferation. Sphingomyelinase is probably a major source of ceramide in cells. Signal transduction mediated by ceramide leads cells to produce cytokine induced apoptosis during several inflammatory responses. SMase are also relevant toxins in several microorganisms. The main objective of this research is to identify SMase activity of T. vaginalis in the total extract (TE, P30, and S30 subfractions from brooked trophozoites. It was found that these fractions of T. vaginalis have SMase activity, which comes principally from P30 subfraction and was mainly type C. Enzymatic activity of SMase increased linearly with time and is pH dependent with two peaks by pH 5.5 and pH 7.5. The addition of manganese to the reaction mixture increased the SMase activity by 1.97.

Antifungal effect of some plant extracts against factors wheat root rot

Science.gov (United States)

Atmaca, Sevim; Şimşek, Şeyda; Denek, Yunus Emre

2017-04-01

Methanol leaf extracts of Humulus lupulus L. and Achillea millefolium L. were evaluated for antifungal activity against economically important phytopathogenic fungi including Fusarium culmorum (W. G. Smith) Sacc. The final concentrations of the methanol extracts obtained from the plants were added to the Potato Dextrose Agar (PDA) at 1%, 2%, 4% and 8% doses. Mycelial disks of pathogens (6 mm in diameter) removed from the margins of a 7 days old culture were transferred to PDA media containing the plant extracts at tested concentrations. Four replicates were used per treatment. For each plant extract and concentration, inhibition of radial growth compared with the untreated control was calculated after 7 days of incubation at 24±1°C, in the dark. Extracts H. lupulus and A. millefolium inhibited the mycelial growth of F. culmorum of mycelial growth of 8% dose of the pathogens by 92.77% and 69.83%, respectively. It has been observed that the antifungal effect of the extracts increases with dose increase. As a result, at least micelle growth and the highest percent inhibition rate were obtained at 8% dose of the extract H. lupulus. H. lupulus extract can be used as a biological preparation.

In vitro antiinflammatory and antioxidant potential of root extracts from Ranunculaceae species

Czech Academy of Sciences Publication Activity Database

Malík, J.; Tauchen, J.; Landa, Přemysl; Kutil, Zsófia; Maršík, Petr; Kloucek, P.; Havlík, J.; Kokoška, L.

2017-01-01

Roč. 109, MAR (2017), s. 128-137 ISSN 0254-6299 R&D Projects: GA ČR(CZ) GA16-07193S Institutional support: RVO:61389030 Keywords : Buttercup family * Cyclooxygenase, fatty acids * Lipoxygenase, medicinal plants * Plant extracts Subject RIV: GM - Food Processing OBOR OECD: Plant sciences, botany Impact factor: 1.427, year: 2016

The numerical simulation on swelling factor and extraction rate of a tight crude oil and SC-CO2 system

Science.gov (United States)

Zou, Hongjun; Gong, Houjian; Li, Yajun; Dong, Mingzhe

2018-03-01

A method was established to study swelling and extraction between CO2 and crude oil, and the influences of pressure, temperature and molecular weight were investigated. Firstly, laboratory analysis was conducted to determine the pseudo-component and other parameters of the crude oil. Then swelling and extraction of the crude oil and SC-CO2 system were calculated by computer simulation. The results show that the pressure and temperature have little influence on the swelling and extraction between CO2 and crude oil when the mole fraction of CO2 is lower. A higher pressure and temperature is more beneficial to the interaction of CO2 and crude oil, while the swelling and extraction will not be obvious when the system is miscible. And the smaller the molecular weight of the oil is, the larger the maximum value of the swelling factor of CO2 and crude oil changes. The study of swelling and extraction plays an important role in the oilfield stimulation.

Moringa Oleifera aqueous leaf extract down-regulates nuclear factor-kappaB and increases cytotoxic effect of chemotherapy in pancreatic cancer cells.

Science.gov (United States)

Berkovich, Liron; Earon, Gideon; Ron, Ilan; Rimmon, Adam; Vexler, Akiva; Lev-Ari, Shahar

2013-08-19

Fewer than 6% patients with adenocarcinoma of the pancreas live up to five years after diagnosis. Chemotherapy is currently the standard treatment, however, these tumors often develop drug resistance over time. Agents for increasing the cytotoxic effects of chemotherapy or reducing the cancer cells' chemo-resistance to the drugs are required to improve treatment outcome. Nuclear factor kappa B (NF-kB), a pro-inflammatory transcription factor, reportedly plays a significant role in the resistance of pancreatic cancer cells to apoptosis-based chemotherapy. This study investigated the effect of aqueous Moringa Oleifera leaf extract on cultured human pancreatic cancer cells - Panc-1, p34, and COLO 357, and whether it can potentiates the effect of cisplatin chemotherapy on these cells. The effect of Moringa Oleifera leaf extract alone and in combination with cisplatin on the survival of cultured human pancreatic cancer cells was evaluated by XTT-based colorimetric assay. The distribution of Panc-1 cells in the cell cycle following treatment with Moringa leaf extract was evaluated by flow cytometry, and evaluations of protein levels were via immunoblotting. Data of cell survival following combined treatments were analyzed with Calcusyn software. Moringa Oleifera leaf extract inhibited the growth of all pancreatic cell lines tested. This effect was significant in all cells following exposure to ≥0.75 mg/ml of the extract. Exposure of Panc-1 cells to Moringa leaf extract induced an elevation in the sub-G1 cell population of the cell-cycle, and reduced the expression of p65, p-IkBα and IkBα proteins in crude cell extracts. Lastly, Moringa Oleifera leaf extract synergistically enhanced the cytotoxic effect of cisplatin on Panc-1 cells. Moringa Oleifera leaf extract inhibits the growth of pancreatic cancer cells, the cells NF-κB signaling pathway, and increases the efficacy of chemotherapy in human pancreatic cancer cells.

Factors influencing treatment decision-making for maintaining or extracting compromised teeth.

Science.gov (United States)

Lang-Hua, Bich Hue; McGrath, Colman P J; Lo, Edward C M; Lang, Niklaus P

2014-01-01

To evaluate treatment decision-making with respect to maintaining periodontally compromised teeth among dentists with or without postgraduate qualifications in implant dentistry. A series of patient scenarios with varying degrees of periodontal disease levels was presented to dental practitioners. Practitioners' decision-making outcome was determined, and intention to retain the compromised teeth was analyzed in bivariate and regression analyses (accounting for postgraduate implant training, gender, years in dental practice, and implant placement experience). This study involved 30 dental practitioners with postgraduate implant qualifications (GDPP), 33 dental practitioners without postgraduate implant qualifications (GDP), and 27 practitioners undergoing training for postgraduate implant qualifications (GDPT). Variations in treatment decision-making were evident between the three groups. Differences in treatment approaches to retaining compromised teeth were apparent. Furthermore, variations in rehabilitation of extracted scenarios existed in terms of use of implant and number of implants need for rehabilitation. Accounting for dentist and practice factors in regression analyses, GDPP/GDPT were three times as likely to retain periodontally compromised upper molar, with or without pain, compared to GDP (without pain OR 3.10, 95%CI 1.04, 10.62 P = 0.04; with pain OR 3.08, 95%CI 1.09, 8.14 P = 0.03). Variations in treatment decision-making with respect to retaining periodontally compromised teeth exist between dental practitioners with and those without postgraduate training in implant dentistry. Furthermore differences in management approaches in how they would retain the teeth or rehabilitate the dental arch were apparent. © 2013 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd.

25 CFR 170.138 - Can roads be built in roadless and wild areas?

Science.gov (United States)

2010-04-01

... RESERVATION ROADS PROGRAM Indian Reservation Roads Program Policy and Eligibility Recreation, Tourism and Trails § 170.138 Can roads be built in roadless and wild areas? Under 25 CFR part 265 no roads can be...

25 CFR 170.209 - How will IRRHPP applications be ranked and funded?

Science.gov (United States)

2010-04-01

... RESERVATION ROADS PROGRAM Indian Reservation Roads Program Funding Irr High Priority Project (irrhpp) § 170... and the following criteria: (1) Existence of safety hazards with documented fatality and injury accidents; (2) Number of years since the tribe's last IRR Program construction project completed; (3...

Physical and physicochemical stability evaluation of cosmetic formulations containing soybean extract fermented by Bifidobacterium animalis

Directory of Open Access Journals (Sweden)

Rafael Pinto Vieira

2009-09-01

Full Text Available Peel off facial masks, based on polyvinyl alcohol (PVA, are formulations that, after application and drying, form an occlusive film over the face. After removing, they provide cleanness, tensor and moisturizing effects, removing dead cells, residues and other materials deposited on the stratum corneous. The soybean extract fermented by Bifidobacterium animalis has sugars, amino acids, peptides, proteins and free isoflavonoids in high concentrations, when compared to the unfermented extract, providing benefits to the cosmetic formulations like anti-aging effect, moisture, tensor action and emollience. The cosmetic bases of peel off facial masks, added with 5.0% w/w of fermented soybean extract, were submitted to Preliminary and Accelerated Stability Studies. Eight (8 preparations were evaluated in several conditions of temperature (-10.0, 5.0, 22.0 and 45.0 ºC and time (maximum of 15 days, comparing the results with the initial condition (48 h after preparation. The variables observed were: organoleptic characteristics, pH and appearing viscosity value and film drying time. The preparation containing 17.0% w/w of PVA and 0.5% w/w of guar gum was selected between the eight preparations initially prepared, because it presented the best performance in the stability test, being recommended storage at low temperatures (5.0 ºC.As máscaras faciais peel off a base de álcool polivinílico (PVA são formulações que, após a aplicação e secagem, formam um filme oclusivo sobre a face e, após sua remoção, conferem limpeza, ação tensora e hidratação à pele, retirando células mortas do estrato córneo, resíduos e outros materiais depositados. O extrato de soja fermentado por Bifidobacterium animalis possui açúcares, aminoácidos, peptídeos, e alto teor de isoflavonas na forma livre, quando comparado ao leite não fermentado, propiciando benefícios às formulações cosméticas, como ação antienvelhecimento, hidratação, efeito tensor e

Cold test of deep groove plarizer for 170 GHz ECCD system

International Nuclear Information System (INIS)

Saigusa, M.; Ookouti, K.; Sazawa, S.; Yuasa, S.; Takei, N.; Takahashi, K.; Sakamoto, K.; Imai, T.

2001-01-01

The single deep groove mirror was proposed as a new concept polarizer instead of the conventional two mirror polarizers for producing ordinary (or extraordinary) wave with high mode purity at an arbitrary injection angle in electron cyclotron current drive (ECCD) experiments. The estimated mode purity of O and X waves on the plasma surface is expected to be higher than about 93% for reasonable ECCD experimental conditions. The three types of deep groove mirrors, which are the rectangular groove mirror and the non-rectangular one, are manufactured and tested at the frequency range from 140 GHz to 170 GHz and the power level of 30 mW. The groove parameters are the period of 0.9-1 mm, the ridge width of 0.45-0.5 mm, and the groove depth of 1.98 mm, which is deeper than a wavelength at 170 GHz. The measured results of deep groove polarizers agree with the theoretical predictions, qualitatively. Those prove the feasibility of a single mirror polarizer for ECCD system

Overcoring rock stress measurements in drillholes ONK-PP169 and ONK-PP170 Olkiluoto

International Nuclear Information System (INIS)

Berg, S.; Sjoeberg, J.

2009-03-01

Three-dimensional overcoring rock stress measurements were conducted in drillholes ONK-PP169 and ONK-PP170 at the 230 m depth level in the ONKALO site ramp. The measurements were performed during the spring of 2008. The objective of the measurements was to obtain better understanding of the in situ stress field for the measured depth levels. Another objective was to increase the confidence and reliability and to diminish the uncertainties concerning the state of stress at shallow depth of ONKALO. Due to problems with bonding of strain gauges, which may have been caused by a thin layer/coating of unknown material on the pilot hole wall, stress measurements results were only achieved in drillhole ONK-PP170 at -230 m level. The initial plan was to conduct measurements at three depth levels, -120 m, -180 m and -220 m levels, in the ONKALO ramp. Two (2) of the conducted measurements could be rated as successful (rating a) two (2) measurement were partly successful (rating b). The results from the measurements assuming isotropic condition, the major principal stress is plunging between 18deg and 35deg and trending between S and WSW. Stress magnitudes (for σ 1 ) varied between 12 and 16 MPa except for test 2:3:3 where a much higher value (47 MPa) was obtained. The orientation of the major principal stress are similar for test 2:3:3 and 2:4:3 (WSW), but are different from the orientation of the major principal stress for test 2:5:1 and 2:6:1 (S). Likewise, the horizontal stresses have the highest values for test 2:3:3 but in this case the orientation is similar to test 2:5:1 and 2:4:3. The horizontal stress magnitudes of test 2:4:3, 2:5:1 and 2:6:1 are similar but the orientation for test 2:6:1 are different from the other three tests. The results from two of the measurements assuming transversely isotropic conditions, the major principal stress is 12.3 MPa and 12.7 MPa, trending WSW and S, plunging 30 deg. (orig.)

Stability Test and Quantitative and Qualitative Analyses of the Amino Acids in Pharmacopuncture Extracted from Scolopendra subspinipes mutilans

Science.gov (United States)

Cho, GyeYoon; Han, KyuChul; Yoon, JinYoung

2015-01-01

Objectives: Scolopendra subspinipes mutilans (S. subspinipes mutilans) is known as a traditional medicine and includes various amino acids, peptides and proteins. The amino acids in the pharmacopuncture extracted from S. subspinipes mutilans by using derivatization methods were analyzed quantitatively and qualitatively by using high performance liquid chromatography (HPLC) over a 12 month period to confirm its stability. Methods: Amino acids of pharmacopuncture extracted from S. subspinipes mutilans were derived by using O-phthaldialdehyde (OPA) & 9-fluorenyl methoxy carbonyl chloride (FMOC) reagent and were analyzed using HPLC. The amino acids were detected by using a diode array detector (DAD) and a fluorescence detector (FLD) to compare a mixed amino acid standard (STD) to the pharmacopuncture from centipedes. The stability tests on the pharmacopuncture from centipedes were done using HPLC for three conditions: a room temperature test chamber, an acceleration test chamber, and a cold test chamber. Results: The pharmacopuncture from centipedes was prepared by using the method of the Korean Pharmacopuncture Institute (KPI) and through quantitative analyses was shown to contain 9 amino acids of the 16 amino acids in the mixed amino acid STD. The amounts of the amino acids in the pharmacopuncture from centipedes were 34.37 ppm of aspartate, 123.72 ppm of arginine, 170.63 ppm of alanine, 59.55 ppm of leucine and 57 ppm of lysine. The relative standard deviation (RSD %) results for the pharmacopuncture from centipedes had a maximum value of 14.95% and minimum value of 1.795% on the room temperature test chamber, the acceleration test chamber and the cold test chamber stability tests. Conclusion: Stability tests on and quantitative and qualitative analyses of the amino acids in the pharmacopuncture extracted from centipedes by using derivatization methods were performed by using HPLC. Through research, we hope to determine the relationship between time and the

BIRD’S NEST EXTRACT CREAM: TREATMENT FOR PERINEAL WOUND IN RATTUS NORVEGICUS

OpenAIRE

Herlina Ofiwijayanti; Syarief Thaufik Hidayat; Nur Khafidhoh

2017-01-01

Background: Perineal rupture occurs almost in all the first labor and not infrequently in the next labor. Complex perineal wounds are at risk for non healing and infection. Objective: This study aims to determine the effect of bird’s nest extract on perineal wound healing on rattus norvegicus. Methods: This was a randomised posttest only group design conducted in October 2016 at Animal Laboratory Unit of Diponegoro University, Semarang. There were 30 samples recruited in this study, div...

Cloud point extraction: an alternative to traditional liquid-liquid extraction for lanthanides(III) separation.

Science.gov (United States)

Favre-Réguillon, Alain; Draye, Micheline; Lebuzit, Gérard; Thomas, Sylvie; Foos, Jacques; Cote, Gérard; Guy, Alain

2004-06-17

Cloud point extraction (CPE) was used to extract and separate lanthanum(III) and gadolinium(III) nitrate from an aqueous solution. The methodology used is based on the formation of lanthanide(III)-8-hydroxyquinoline (8-HQ) complexes soluble in a micellar phase of non-ionic surfactant. The lanthanide(III) complexes are then extracted into the surfactant-rich phase at a temperature above the cloud point temperature (CPT). The structure of the non-ionic surfactant, and the chelating agent-metal molar ratio are identified as factors determining the extraction efficiency and selectivity. In an aqueous solution containing equimolar concentrations of La(III) and Gd(III), extraction efficiency for Gd(III) can reach 96% with a Gd(III)/La(III) selectivity higher than 30 using Triton X-114. Under those conditions, a Gd(III) decontamination factor of 50 is obtained.

Exposure Factors Resources: Contrasting EPA’s Exposure Factors Handbook with International Sources (Journal Article)

Science.gov (United States)

Efforts to compile and standardize exposure human factors have resulted in the development of a variety of resources available to the scientific community. For example, the U.S. EPA developed the Exposure Factors Handbook and Child-specific Exposure Factors Handbook to promote c...

Lavandula angustifolia extract improves deteriorated synaptic plasticity in an animal model of Alzheimer’s disease

Science.gov (United States)

Soheili, Masoud; Tavirani, Mostafa Rezaei; Salami, Mahmoud

2015-01-01

Objective(s): Neurodegenerative Alzheimer’s disease (AD) is associated with profound deficits in synaptic transmission and synaptic plasticity. Long-term potentiation (LTP), an experimental form of synaptic plasticity, is intensively examined in hippocampus. In this study we evaluated the effect of aqueous extract of lavender (Lavandula angustifolia) on induction of LTP in the CA1 area of hippocampus. In response to stimulation of the Schaffer collaterals the baseline or tetanized field extracellular postsynaptic potentials (fEPSPs) were recorded in the CA1 area. Materials and Methods: The electrophysiological recordings were carried out in four groups of rats; two control groups including the vehicle (CON) and lavender (CE) treated rats and two Alzheimeric groups including the vehicle (ALZ) and lavender (AE) treated animals. Results: The extract inefficiently affected the baseline responses in the four testing groups. While the fEPSPs displayed a considerable LTP in the CON animals, no potentiation was evident in the tetanized responses in the ALZ rats. The herbal medicine effectively restored LTP in the AE group and further potentiated fEPSPs in the CE group. Conclusion: The positive effect of the lavender extract on the plasticity of synaptic transmission supports its previously reported behavioral effects on improvement of impaired spatial memory in the Alzheimeric animals. PMID:26949505

Lavandula angustifolia extract improves deteriorated synaptic plasticity in an animal model of Alzheimer’s disease

Directory of Open Access Journals (Sweden)

Masoud Soheili

2015-11-01

Full Text Available Objective(s:Neurodegenerative Alzheimer’s disease (AD is associated with profound deficits in synaptic transmission and synaptic plasticity. Long-term potentiation (LTP, an experimental form of synaptic plasticity, is intensively examined in hippocampus. In this study we evaluated the effect of aqueous extract of lavender (Lavandula angustifolia on induction of LTP in the CA1 area of hippocampus. In response to stimulation of the Schaffer collaterals the baseline or tetanized field extracellular postsynaptic potentials (fEPSPs were recorded in the CA1 area. Materials and Methods: The electrophysiological recordings were carried out in four groups of rats; two control groups including the vehicle (CON and lavender (CE treated rats and two Alzheimeric groups including the vehicle (ALZ and lavender (AE treated animals. Results: The extract inefficiently affected the baseline responses in the four testing groups. While the fEPSPs displayed a considerable LTP in the CON animals, no potentiation was evident in the tetanized responses in the ALZ rats. The herbal medicine effectively restored LTP in the AE group and further potentiated fEPSPs in the CE group. Conclusion:The positive effect of the lavender extract on the plasticity of synaptic transmission supports its previously reported behavioral effects on improvement of impaired spatial memory in the Alzheimeric animals.

Factors affecting sodium hypochlorite extraction of CCA from treated wood.

Science.gov (United States)

Gezer, E D; Cooper, P A

2009-12-01

Significant amounts of chromated copper arsenate (CCA) treated wood products, such as utility poles and residential construction wood, remain in service. There is increasing public concern about environmental contamination from CCA-treated wood when it is removed from service for reuse or recycling, placed in landfills or burned in commercial incinerators. In this paper, we investigated the effects of time, temperature and sodium hypochlorite concentration on chromium oxidation and extraction of chromated copper arsenate from CCA-treated wood (Type C) removed from service. Of the conditions evaluated, reaction of milled wood with sodium hypochlorite for one hour at room temperature followed by heating at 75 degrees C for two hours gave the highest extraction efficiency. An average of 95% Cr, 99% Cu and 96% As could be removed from CCA-treated, milled wood by this process. Most of the extracted chromium was oxidized to the hexavalent state and could therefore be recycled in a CCA treating solution. Sodium hypochlorite extracting solutions could be reused several times to extract CCA components from additional treated wood samples.

Measurement of jet quenching with semi-inclusive hadron-jet distributions in central Pb-Pb collisions at root s(NN)=2.76 TeV

Czech Academy of Sciences Publication Activity Database

Adam, J.; Adamová, Dagmar; Bielčík, J.; Bielčíková, Jana; Brož, M.; Čepila, J.; Contreras, J. G.; Eyyubova, G.; Ferencei, Jozef; Křelina, M.; Křížek, Filip; Kučera, Vít; Kushpil, Svetlana; Mareš, Jiří A.; Petráček, V.; Pospíšil, Jan; Schulc, M.; Špaček, M.; Šumbera, Michal; Vajzer, Michal; Vaňát, Tomáš; Závada, Petr

2015-01-01

Roč. 2015, č. 9 (2015), s. 170 ISSN 1029-8479 R&D Projects: GA MŠk(CZ) LG13031 Institutional support: RVO:68378271 ; RVO:61389005 Keywords : ALICE collaboration * quark gluon plasma * jet physics * heavy ions Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders; BF - Elementary Particles and High Energy Physics (FZU-D) Impact factor: 6.023, year: 2015

Brassica oleracea L. var. Italica Plenck and Cassia absus L. extracts reduce oxidative stress, alloxan induced hyperglycemia and indices of diabetic complications

International Nuclear Information System (INIS)

Khalid, S.; Tipu, M.K.; Ali, H.

2018-01-01

The nature's endowment of medicinal plants in successful management of diabetes necessitates their further exploration. Therefore, the present study was designed to comprehend ameliorating role of Brassica oleracea var. italic (BO) and Cassia absus (CA) in oxidative stress, hyperglycemia and indices of diabetic complications. Among all the extracts of BO and CA, aqueous extract was the most proficient in terms of extract recovery (9.0 and 10.2%) and DPPH radical scavenging efficiency (IC50 = 11.90 +- 1.70 and 8.26 +- 1.20 mu g/ml) respectively. Maximum phenolic content [BO = 184.0 +- 0.17 and CA = 406.7 +- 0.08 mu g gallic acid equivalent/mg extract (E)], flavonoid content (BO = 160.9 +- 0.1 and CA = 361.9 +- 0.09 mu g quercetin equivalent/mg E) and total antioxidant capacity (BO = 223.7 +- 0.20 and CA = 257.2 +- 3.30 mu g ascorbic acid equivalent/mg E) was recorded in their ethanol extract. Highest reducing power potential was quantified in BO ethanol and CA aqueous extractsas 427.9 +- 0.10 and 480.0 +- 2.10mu g ascorbic acid equivalent/mg E respectively. Brine shrimp assay expounded petroleum ether extract of BO and CA to have some cytotoxicity (LC50 = 200+- 2.3 and 86.6 +- 3.1 mu g/ml respectively). In vivo studies established their aqueous extract as proficient in reducing the serum glucose (BO = 142.3 +- 7.10 and CA = 161.5 +- 4.40 mg/dl at day 21) as well as blood cholesterol, ALT and urea levels. Findings of the present study prospects BO and CA a useful treatment of diabetes and its escorting complications. (author)

On the Road to Genetic Boolean Matrix Factorization

Czech Academy of Sciences Publication Activity Database

Snášel, V.; Platoš, J.; Krömer, P.; Húsek, Dušan; Frolov, A.

2007-01-01

Roč. 17, č. 6 (2007), s. 675-688 ISSN 1210-0552 Institutional research plan: CEZ:AV0Z10300504 Keywords : data mining * genetic algorithms * Boolean factorization * binary data * machine learning * feature extraction Subject RIV: IN - Informatics, Computer Science Impact factor: 0.280, year: 2007

A method for efficient extraction of rotifers (Rotifera) from soils

Czech Academy of Sciences Publication Activity Database

Devetter, Miloslav

2010-01-01

Roč. 53, č. 2 (2010), s. 115-118 ISSN 0031-4056 R&D Projects: GA ČR(CZ) GP206/06/P405 Institutional research plan: CEZ:AV0Z60660521 Keywords : soil rotifers * Bdelloids * quantitative extraction Subject RIV: EH - Ecology, Behaviour Impact factor: 1.474, year: 2010

Tick salivary gland extract-activated transmission of Borrelia afzelii spirochaetes

Czech Academy of Sciences Publication Activity Database

Pechová, Jitka; Tresová, Gabriela; Kovář, Lubomír; Kopecký, Jan

2002-01-01

Roč. 49, č. 2 (2002), s. 153ů159 ISSN 0015-5683 R&D Projects: GA ČR GA524/02/0901 Institutional research plan: CEZ:AV0Z6022909 Keywords : Ixodes ricinus * salivary gland extract * Borrelia afzelii Subject RIV: EC - Immunology Impact factor: 0.515, year: 2002

45 CFR 170.455 - Testing and certification to newer versions of certain standards.

Science.gov (United States)

2010-10-01

... INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.455 Testing and certification to newer versions of certain standards. (a) ONC-ATCBs...

New resource nationalism? Continuity and change in Tanzania’s extractive industries

DEFF Research Database (Denmark)

Jacob, Thabit; Pedersen, Rasmus Hundsbæk

2018-01-01

in July 2017. Combined, the new acts aim to regain the loss of the country’s sovereignty over its resources, first and foremost by opening the renegotiation of existing contracts and removing firms’ access to international arbitration. Such actions have renewed the debate on resource nationalism......, with some political commentators referring to ‘a new resource nationalism’, supposedly marking a break with the previous administration. By analysing changes in extractive governance in recent years, this article argues that, whereas some new features related to the current President’s personality...... and populist style may explain some of the new nationalism, the continuities from previous administration are more pronounced. This can be seen in the repeated calls for a tougher fiscal take, involvement of state-owned enterprises and presidents’ direct involvement in deal-making, all of which were already...

Isolation of quaternary benzo[c]phenanthridine alkaloids from Macleaya microcarpa (MAXIM.) FEDDE: Comparison of maceration, Soxhlet extraction and pressurized liquid extraction

Czech Academy of Sciences Publication Activity Database

Urbanová, J.; Pěnčíková, K.; Gregorová, J.; Hohnová, Barbora; Šťavíková, Lenka; Karásek, Pavel; Roth, Michal; Táborská, E.

2012-01-01

Roč. 23, č. 5 (2012), s. 477-482 ISSN 0958-0344 R&D Projects: GA ČR(CZ) GAP206/11/0138; GA ČR(CZ) GPP503/11/P523 Institutional research plan: CEZ:AV0Z40310501 Keywords : benzo[c]phenanthridine alkaloids * extraction methods * Macleaya microcarpa Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 2.480, year: 2012

Z4-symmetric factorized S-matrix in two space-time dimensions

International Nuclear Information System (INIS)

Zamolodchikov, A.B.

1979-01-01

The factorized S-matrix with internal symmetry Z 4 is constructed in two space-time dimensions. The two-particle amplitudes are obtained by means of solving the factorization, unitarity and analyticity equations. The solution of factorization equations can be expressed in terms of elliptic functions. The S-matrix cotains the resonance poles naturally. The simple formal relation between the general factorized S-matrices and the Baxter-type lattice transfer matrices is found. In the sense of this relation the Z 4 -symmetric S-matrix corresponds to the Baxter transfer matrix itself. (orig.)

Growth rate of bacteria is affected by soil texture and extraction procedure

Czech Academy of Sciences Publication Activity Database

Uhlířová, Eva; Šantrůčková, Hana

2003-01-01

Roč. 35, - (2003), s. 217-224 ISSN 0038-0717 Institutional research plan: CEZ:AV0Z6066911 Keywords : soil texture * extraction of bacteria * biosynthetic activity of bacteria Subject RIV: EH - Ecology, Behaviour Impact factor: 1.915, year: 2003

The anti-inflammatory activity of standard aqueous stem bark extract of Mangifera indica L. as evident in inhibition of Group IA sPLA2.

Science.gov (United States)

Dhananjaya, Bhadrapura Lakkappa; Shivalingaiah, Sudharshan

2016-03-01

The standard aqueous stem bark extract is consumed as herbal drink and used in the pharmaceutical formulations to treat patients suffering from various disease conditions in Cuba. This study was carried out to evaluate the modulatory effect of standard aqueous bark extract of M. indica on Group IA sPLA2. M. indica extract, dose dependently inhibited the GIA sPLA2 (NN-XIa-PLA2) activity with an IC50 value 8.1 µg/ml. M. indica extract effectively inhibited the indirect hemolytic activity up to 98% at ~40 µg/ml concentration and at various concentrations (0-50 µg/ml), it dose dependently inhibited the edema formation. When examined as a function of increased substrate and calcium concentration, there was no relieve of inhibitory effect on the GIA sPLA2. Furthermore, the inhibition was irreversible as evidenced from binding studies. It is observed that the aqueous extract ofM. indica effectively inhibits sPLA2 and it is associated inflammatory activities, which substantiate their anti-inflammatory properties. The mode of inhibition could be due to direct interaction of components present in the extract, with sPLA2 enzyme. Further studies on understanding the principal constituents, responsible for the anti-inflammatory activity would be interesting to develop this into potent anti-inflammatory agent.

Measurements of the Higgs boson production and decay rates and constraints on its couplings from a combined ATLAS and CMS analysis of the LHC pp collision data at √s = 7 and 8 TeV

Czech Academy of Sciences Publication Activity Database

Aad, G.; Abbott, B.; Abdallah, J.; Chudoba, Jiří; Havránek, Miroslav; Hejbal, Jiří; Jakoubek, Tomáš; Kepka, Oldřich; Kupčo, Alexander; Kůs, Vlastimil; Lokajíček, Miloš; Lysák, Roman; Marčišovský, Michal; Mikeštíková, Marcela; Němeček, Stanislav; Penc, Ondřej; Šícho, Petr; Staroba, Pavel; Svatoš, Michal; Taševský, Marek; Vrba, Václav

2016-01-01

Roč. 2016, č. 8 (2016), s. 1-70, č. článku 045. ISSN 1029-8479 Institutional support: RVO:68378271 Keywords : hadron-hadron scattering (experiments) * Higgs physics * ATLAS * CMS * CERN Subject RIV: BF - Elementary Particles and High Energy Physics Impact factor: 6.063, year: 2016

Effects of selected Indonesian plant extracts on E. cuniculi infection in vivo

Czech Academy of Sciences Publication Activity Database

Sak, Bohumil; Jandova, Anna; Doležal, Karel; Kváč, Martin; Květoňová, Dana; Hlásková, Lenka; Rost, M.; Olšanský, M.; Nurcahyo, W.; Foitová, I.

2017-01-01

Roč. 181, OCT (2017), s. 94-101 ISSN 0014-4894 R&D Projects: GA ČR(CZ) GAP505/11/1163; GA ČR GA14-20684S Institutional support: RVO:60077344 ; RVO:61389030 Keywords : molecular detection * antifungal * plant extract * Encephalitozoon cuniculi * in vivo Subject RIV: EG - Zoology OBOR OECD: Zoology Impact factor: 1.724, year: 2016

The use of artificial spawning substrates in order to understand the factors influencing the spawning site selection, depth of egg strands deposition and hatching time of perch (Perca fluviatilis L.)

Czech Academy of Sciences Publication Activity Database

Čech, Martin; Vejřík, L.; Peterka, Jiří; Říha, Milan; Muška, Milan; Jůza, Tomáš; Draštík, Vladislav; Kratochvíl, Michal; Kubečka, Jan

2012-01-01

Roč. 71, č. 1 (2012), s. 170-179 ISSN 1129-5767 R&D Projects: GA ČR(CZ) GP206/09/P266 Institutional support: RVO:60077344 Keywords : SCUBA diving * aquatic vegetation * lake management * common stonewort Chara vulgaris * Eurasian water milfoil Myriophyllum spicatum Subject RIV: EG - Zoology Impact factor: 1.473, year: 2012

Extraction of Botanical Pesticides from Pelargonium graveolens using Supercritical Carbon Dioxide

Czech Academy of Sciences Publication Activity Database

Machalová, Zdeňka; Sajfrtová, Marie; Pavela, R.; Topiař, Martin

2015-01-01

Roč. 67, MAY (2015), s. 310-317 ISSN 0926-6690 R&D Projects: GA TA ČR TA01010578 Institutional support: RVO:67985858 Keywords : botanical pesticides * geranium oil * supercritical fluid extraction Subject RIV: CI - Industrial Chemistry, Chemical Engineering Impact factor: 3.449, year: 2015

Spectroscopic factor of the 7He ground state

International Nuclear Information System (INIS)

Beck, F.; Frekers, D.; Neumann-Cosel, P. von; Richter, A.; Ryezayeva, N.; Thompson, I.J.

2007-01-01

The neutron spectroscopic factor S n of the 7 He ground state is extracted from an R-matrix analysis of a recent measurement of the 7 Li(d, 2 He) 7 He reaction with good energy resolution. The width extracted from a deconvolution of the spectrum is Γ=183(22) keV (full width at half maximum, FWHM). The result S n =0.64(9) is slightly larger than predictions of recent 'ab initio' Green's function Monte Carlo and fermionic molecular dynamics calculations

Swimmer’s itch: etiology, impact, and risk factors in Europe

Czech Academy of Sciences Publication Activity Database

Soldánová, Miroslava; Selbach, C.; Kalbe, M.; Kostadinova, Aneta; Sures, B.

2013-01-01

Roč. 29, č. 2 (2013), s. 65-74 ISSN 1471-4922 R&D Projects: GA ČR GAP505/10/1562 Institutional support: RVO:60077344 Keywords : bird schistosomes * Trichobilharzia * swimmer's itch * Lymnaeidae * ecological factors * risk factors * Europe Subject RIV: EC - Immunology Impact factor: 6.217, year: 2013 http://www.sciencedirect.com/science/article/pii/S1471492212002000

Solvent Extraction of Rare Earths by Di-2 Ethylhexyl Phosphoric Acid

International Nuclear Information System (INIS)

Srinuttrakul, Wannee; Kranlert, Kannika; Kraikaew, Jarunee; Pongpansook, Surasak; Chayavadhanangkur, Chavalek; Kranlert, Kannika

2004-10-01

Solvent extraction has been widely applied for individual rare earth separation because the separation time is rapid and a large quantity of products is obtained. In this work, this technique was utilized to extract mixed rare earths, obtained from monazite digestion process. Di-2-ethylhexyl phosphoric acid (D2EHPA) was used as an extractant. The factors affected the extraction including HNO 3 concentration in mixed rare earth nitrate solution and the amount of D2EHPA were studied. The appropriate concentrations of HNO 3 and D2EHPA were found to be 0.01 and 1.5 M, respectively. From the result of equilibrium curve study, it was observed that heavy rare earths were extracted more efficient than light rare earths. A 6-stage continuous countercurrent solvent extraction was simulated for rare earth extraction. The optimum ratio of solvent to feed solution (S/F) was 2. Because of the high cost of D2EHPA, 1.0 M of D2EHPA was suitable for the rare earth extraction by the continuous countercurrent solvent extraction

Probiotic modulation of the gut bacterial community of juvenile Litopenaeus vannamei challenged with Vibrio parahaemolyticus CAIM 170

Directory of Open Access Journals (Sweden)

Irasema E Luis-Villaseñor

2015-09-01

Full Text Available The protective effects of two probiotic mixtures was studied using the fingerprints of the bacterial community of Litopenaeus vannamei juveniles exposed to probiotics and challenged with Vibrio parahaemolyticus CAIM 170. Fingerprints were constructed using 16S rRNA gene and the PCR-SSCP (Single strand conformation polymorphism technique, and the probiotics used were an experimental Bacillus mixture (Bacillus tequilensis YC5-2 + B. endophyticus C2-2 and YC3-B and the commercial probiotic Alibio. The DNA for PCR-SSCP analyses was extracted directly from the guts of shrimps treated for 20 days with the probiotics and injected with 2.5*10(5 CFU g-1 of V. parahaemolyticus one week after suspension of the probiotic treatment. Untreated shrimps served as positive (injected with V. parahaemolyticus and negative (not injected controls Analysis of the bacterial community carried out after inoculation and 12 and 48 h later confirmed that V. parahaemolyticus was present in shrimps of the positive control , but not in the negative control or treated with the probiotic mixtures. A significant difference in the diversity of the bacterial community was observed between times after infection. The band patterns in 0-12 h were clustered into a different group from that determined after 48 h, and suggested that during bacterial infection the guts of whiteleg shrimp were dominated by gamma proteobacteria represented by Vibrio sp. and Photobacterium sp. Our results indicate that the experimental and the commercial mixtures are suitable to modulate the bacterial community of L. vannamei and could be used as a probiotic to control vibriosis in juvenile shrimp.

Measures of Ruleset Quality for General Rules Extraction Methods

Czech Academy of Sciences Publication Activity Database

Holeňa, Martin

2009-01-01

Roč. 50, č. 6 (2009), s. 867-879 ISSN 0888-613X R&D Projects: GA ČR GA201/08/0802 Institutional research plan: CEZ:AV0Z10300504 Keywords : rules extraction from data * quality measures * ruleset measures * ROC curves * observational logic * fuzzy logic Subject RIV: IN - Informatics, Computer Science Impact factor: 2.090, year: 2009

Effects of Andrographis paniculata and Orthosiphon stamineus Extracts on the Glucuronidation of 4-Methylumbelliferone in Human UGT Isoforms

Directory of Open Access Journals (Sweden)

Sabariah Ismail

2010-05-01

Full Text Available The effects of Andrographis paniculata and Orthosiphon stamineus extracts on the in vitro glucuronidation of 4-methylumbelliferone (4MU by recombinant human UGTs, UGT1A1, UGT1A3, UGT1A6, UGT1A7, UGT1A8, UGT1A10, UGT2B7 and UGT2B15 were determined. The potential inhibitory effects of both of the extracts on the activity of each of the UGT isoforms were investigated using 4MU as the substrate. Incubations contained UDP-glucuronic acid (UDPGA as the cofactor, MgCl2, cell lysate of respective isoform, and 4MU at the approximate apparent Km or S50 value of each isoform. Final concentrations of Andrographis paniculata and Orthosiphon stamineus extracts used were 0.025, 0.25, 2.5, 25 and 50 μg/mL and 0.01, 0.10, 1.0, 10 and 50 μg/mL respectively. Both extracts variably inhibited the activity of most of the isoforms in a concentration dependent manner. Andrographis paniculata extract was the better inhibitor of all the isoforms studied (IC50 1.70 μg/mL for UGT1A3, 2.57 μg/mL for UGT1A8, 2.82 μg/mL for UGT2B7, 5.00 μg/mL for UGT1A1, 5.66 μg/mL for UGT1A6, 9.88 μg/mL for UGT1A7 and 15.66 μg/mL for UGT1A10. Both extracts showed less than 70% inhibition of UGT2B15, so the IC50 values were >50μg/mL. The inhibition of human UGTs by Andrographis paniculata and Orthosiphon stamineus extracts in vitro suggests a potential for drug-herbal extract interactions in the therapeutic setting.

Homogenate extraction of crude polysaccharides from Lentinus edodes and evaluation of the antioxidant activity

Directory of Open Access Journals (Sweden)

Leqin KE

2016-01-01

Full Text Available Abstract Crude polysaccharides of Lentinus edodes were extracted using homogenate method. Factors affecting the yield of crude polysaccharides were investigated and optimized by response surface methodology. The homogenate extraction method was compared with traditional heating extraction method. The antioxidant activity of crude polysaccharides from Lentinus edodes was evaluated. Results showed that, the optimal conditions of homogenate extraction were as follows: solvent pH, 10; liquid-solid ratio, 30: 1 (mL: g, extraction time, 66 s; number of extraction, 1. Under these conditions, the yield of crude polysaccharides was (13.2 ± 0.9%, which was 29.82% higher than that of traditional heating extraction. Crude polysaccharides of Lentinus edodes had good DPPH scavenging activity. Compared with the traditional heating extraction, the homogenate extraction had notable advantages including good extraction yield, short extraction time and low extraction temperature. It is an efficient way to extract crude polysaccharides from Lentinus edodes.

Modeling the Supercritical Fluid Extraction of Essential Oils from Plant Materials

Czech Academy of Sciences Publication Activity Database

Sovová, Helena

2012-01-01

Roč. 1250, SI (2012), s. 27-33 ISSN 0021-9673 R&D Projects: GA TA ČR TA01010578 Institutional support: RVO:67985858 Keywords : supercritical fluid extraction * essential oils * model for kinetics Subject RIV: CI - Industrial Chemistry, Chemical Engineering Impact factor: 4.612, year: 2012

Pressurized hot water extraction of proteins from Sambucus nigra L. branches

Czech Academy of Sciences Publication Activity Database

Šalplachta, Jiří; Hohnová, Barbora

2017-01-01

Roč. 108, DEC (2017), s. 312-315 ISSN 0926-6690 Grant - others:GA AV ČR(CZ) R200311521 Institutional support: RVO:68081715 Keywords : elderberry * pressurized hot water extraction * proteins Subject RIV: CB - Analytical Chemistry, Separation OBOR OECD: Analytical chemistry Impact factor: 3.181, year: 2016

Nano-electromembrane extraction

DEFF Research Database (Denmark)

Payán, María D Ramos; Li, Bin; Petersen, Nickolaj J.

2013-01-01

as extraction selectivity. Compared with conventional EME, the acceptor phase volume in nano-EME was down-scaled by a factor of more than 1000. This resulted in a very high enrichment capacity. With loperamide as an example, an enrichment factor exceeding 500 was obtained in only 5 min of extraction...... electrophoresis (CE). In that way the sample preparation performed by nano-EME was coupled directly with a CE separation. Separation performance of 42,000-193,000 theoretical plates could easily be obtained by this direct sample preparation and injection technique that both provided enrichment as well...

Determination of astrophysical 13N(p, γ)14O S-factors from the asymptotic normalization coefficient of 14C→13C + n

International Nuclear Information System (INIS)

Guo Bing; Li Zhihong

2007-01-01

The angular distribution of the 13 C(d,p) 14 C reaction is reanalysed using the Johnson-Soper approach. The squared asymptotic normalization coefficient (ANC) of virtual decay 14 C→ 13 C + n is then derived to be 21.4 ± 5.0 fm -1 . The squared ANC and spectroscopic factor (SF) of 14 O→ 13 N + p are extracted to be 30.4 ± 7.1 fm -1 and 1.94 ± 0.45, respectively. The astrophysical S-factors and reaction rates of 13 N(p, γ) 14 O are determined from the ANC of 14 O→ 13 N + p using the R-matrix approach. (authors)

The activity of the acidic phosphoproteins from the 80 S rat liver ribosome.

Science.gov (United States)

MacConnell, W P; Kaplan, N O

1982-05-25

The selective removal of acidic phosphoproteins from the 80 S rat liver ribosome was accomplished by successive alcohol extractions at low salt concentration. The resulting core ribosomes lost over 90% of their translation activity and were unable to support the elongation factor 2 GTPase reaction. Both activities were partially restored when the dialyzed extracts were added back to the core ribosome. The binding of labeled adenosine diphosphoribosyl-elongation factor 2 to ribosomes was also affected by extraction and could be reconstituted, although not to the same extent as the GTPase activity associated with elongation factor 2 in the presence of the ribosome. The alcohol extracts of the 80 S ribosome contained mostly phosphoproteins P1 and P2 which could be dephosphorylated and rephosphorylated in solution by alkaline phosphatase and protein kinase, respectively. Dephosphorylation of the P1/P2 mixture in the extracts caused a decrease in the ability of these proteins to reactivate the polyphenylalanine synthesis activity of the core ribosome. However, treatment of the dephosphorylated proteins with the catalytic subunit of 3':5'-cAMP-dependent protein kinase in the presence of ATP reactivated the proteins when compared to the activity of the native extracts. Rabbit antisera raised against the alcohol-extracted proteins were capable of impairing both the polyphenylalanine synthesis reaction and the elongation factor 2-dependent GTPase reaction in the intact ribosomes.

Solvent extraction of uranium, thorium, and rare earths with dialkyldithiophosphoric acids

International Nuclear Information System (INIS)

Haiduc, I.; Curtui, M.

1986-01-01

The separation conditions for throium (IV) in the presence of trivalent rare earths was investigated. The distribution ratios (D), extraction effectivity values (E%) and separation factor(S) were calculated for binary systems Th-La, Th-Ce, Th-Pr, Th-Sm. Di-(2-ethyl-hexyl)dithiophosphoric acid (HEhdtp) alone or mixtures of HEhdtp and trioctylphosphoshine oxide (TOPO) can be successfully used for separation of Thorium (IV) and rare earths

Huaier Extract Induces Autophagic Cell Death by Inhibiting the mTOR/S6K Pathway in Breast Cancer Cells.

Directory of Open Access Journals (Sweden)

Xiaolong Wang

Full Text Available Huaier extract is attracting increased attention due to its biological activities, including antitumor, anti-parasite and immunomodulatory effects. Here, we investigated the role of autophagy in Huaier-induced cytotoxicity in MDA-MB-231, MDA-MB-468 and MCF7 breast cancer cells. Huaier treatment inhibited cell viability in all three cell lines and induced various large membranous vacuoles in the cytoplasm. In addition, electron microscopy, MDC staining, accumulated expression of autophagy markers and flow cytometry revealed that Huaier extract triggered autophagy. Inhibition of autophagy attenuated Huaier-induced cell death. Furthermore, Huaier extract inhibited the mammalian target of the rapamycin (mTOR/S6K pathway in breast cancer cells. After implanting MDA-MB-231 cells subcutaneously into the right flank of BALB/c nu/nu mice, Huaier extract induced autophagy and effectively inhibited xenograft tumor growth. This study is the first to show that Huaier-induced cytotoxicity is partially mediated through autophagic cell death in breast cancer cells through suppression of the mTOR/S6K pathway.

Associated Factors and Quality of Care Received among Maternal ...

African Journals Online (AJOL)

USER

discussions with health staff to assess care received and factors leading to death. A total of 43 maternal deaths ... department with bed capacity of 105, one ..... evidence for emergency obstetric care. ... Planning; 15(2): 170-176. 13. Ray S ...

Synaptojanin 1: localization on coated endocytic intermediates in nerve terminals and interaction of its 170 kDa isoform with Eps15

DEFF Research Database (Denmark)

Haffner, C; Takei, K; Chen, H

1997-01-01

that synaptojanin-170, an alternatively spliced isoform of synaptojanin 1, binds Eps15, a clathrin coat-associated protein. Binding is mediated by the COOH-terminal region of synaptojanin-170 which we show here to be poorly conserved from rat to humans, but to contain in both species three asparagine...

Effective extractants for the extraction of lithium from aqueous solutions containing sodium and potassium compounds

International Nuclear Information System (INIS)

Marinkina, G.A.; Zanina, A.S.; Shergina, S.I.; Sokolov, I.E.; Kotlyarevskii, I.L.

1992-01-01

The extraction power of newly obtained pure methoxy-1,3-diketones in diluents and in their mixtures with electron-donating additives during the extraction of lithium from aqueous solutions containing sodium and potassium was investigated. High separation factors were obtained; no appreciable amounts of sodium and potassium were found in the extract after total extraction of the lithium. 9 refs., 2 figs., 8 tabs

78 FR 32270 - U.S. Extractive Industries Transparency Initiative Multi-Stakeholder Group (USEITI MSG) Advisory...

Science.gov (United States)

2013-05-29

... DEPARTMENT OF THE INTERIOR Office of the Secretary [Docket No. ONRR-2012-0003; DS63600000 DR2PS0000.PX8000 134D0102R2] U.S. Extractive Industries Transparency Initiative Multi- Stakeholder Group... Transparency Initiative (USEITI) Multi- Stakeholder Group Advisory Committee. DATES: The meetings will be held...

FACTORS RESPONSIBLE FOR CONSUMER’S ATTITUDE TOWARDS ADVERGAMES

Directory of Open Access Journals (Sweden)

Ghirvu Alina

2013-07-01

Full Text Available Internet technology, as well as development of mobile phone was fast adopted by people for recreational, economical and business reasons. The Internet technology development and the new communication systems made marketers to orientate their promotional campaigns and efforts towards new ways of reaching their actual and potential client. They started to use new and innovative ways to get public’s interest and to encourage purchase. In this context, Internet offered a complex environment to support the development of innovative brand strategies. One of the emerging new techniques in advertising is advergaming. Advergames represent the use of video game interactive technology for delivering brand messages to public. They are electronic games accessible on companies own websites, on social media sites and on application which can be downloaded on mobile devices. For marketers is important to understand the way that advergames work and what consumer’s attitude towards this practice is. The formation of attitude depends on a series of factors which are common to all types of advertisements based on Internet technology. These factors responsible for consumers’ attitude towards online advertising and implicit for attitude formation over advergames are informative component, entertainment, source credibility and irritation. Beside these four elements, there are additional criterions which consumers use for evaluating advertising in video games: the viral component, interactivity and telepresence. For marketers it is important to understand these factors and to find practical ways for using them for a better brand communication and for higher result of advertising campaigns which include the use of advergames as part of the promotional strategy. The present paper is looking to make a description of the factors influencing consumer’s attitude formation towards advergames, in conjunction with the Internet environment and the specific features of

Extraction and determination of total flavonoids in jujube by alcohol extraction

Science.gov (United States)

Ji, Y. B.; Ru, X.; Yu, M.; Wang, S. W.; Lu, L.; Qiao, A. N.; Guo, A. Z.

2017-12-01

Jujube is a ripe fruit of Rhamnaceae. Its main active component is flavonoids, so the extraction and determination of total flavonoids in jujube will help to develop and utilize the medicinal value of jujube. In this study, the total flavonoids were extracted from jujube by alcohol extraction method. Through single factor investigation and orthogonal test, it was found that the total flavonoids content in jujube was the highest under the condition of 70°C, material ratio of 1:40, and extraction of 30 min by 70% ethanol. The content of total flavonoids in the extract of jujube was 1.57% at the wavelength of 510 nm by UV and rutin as the standard. The method was evaluated by methodological study, and it was determined that this method could be used as the detection of total flavonoids in jujube extraction.

SEPARATION OF p-AMINOBENZOIC ACID BY REACTIVE EXTRACTION. 1. MECHANISM AND INFLUENCING FACTORS

Directory of Open Access Journals (Sweden)

DAN CASCAVAL

2008-09-01

Full Text Available The comparative study on the reactive extraction of p-aminobenzoic acid with Amberlite LA-2 and D2EHPA in two solvents with different polarity (n-heptane and dichloromethane indicated that the extractant type and solvent polarity control the extraction mechanism. Thus, the reactive extraction with Amberlite LA-2 occurs by means of the interfacial formation of an aminic adduct with three extractant molecules in low-polar solvent, or of an salt with one extractant molecule in higher polar solvent. Similarly, the extraction with D2EHPA is based on the formation of an acidic adduct with two extractant molecules in n-heptane, or of a salt with one extractant molecule in dichloromethane. The most efficient extraction has been reached for the combination Amberlite LA-2-dichloromethane.

Analysis of the flood extent extraction model and the natural flood influencing factors: A GIS-based and remote sensing analysis

International Nuclear Information System (INIS)

Lawal, D U; Matori, A N; Yusuf, K W; Hashim, A M; Balogun, A L

2014-01-01

Serious floods have hit the State of Perlis in 2005, 2010, as well as 2011. Perlis is situated in the northern part of Peninsula Malaysia. The floods caused great damage to properties and human lives. There are various methods used in an attempt to provide the most reliable ways to reduce the flood risk and damage to the optimum level by identifying the flood vulnerable zones. The purpose of this paper is to develop a flood extent extraction model based on Minimum Distance Algorithm and to overlay with the natural flood influencing factors considered herein in order to examine the effect of each factor in flood generation. GIS spatial database was created from a geological map, SPOT satellite image, and the topographical map. An attribute database was equally created from field investigations and historical flood areas reports of the study area. The results show a great correlation between the flood extent extraction model and the flood factors

25 CFR 170.806 - What is an IRR Transportation Facilities Maintenance Management System?

Science.gov (United States)

2010-04-01

... AND WATER INDIAN RESERVATION ROADS PROGRAM BIA Road Maintenance § 170.806 What is an IRR Transportation Facilities Maintenance Management System? An IRR Transportation Facilities Maintenance Management... 25 Indians 1 2010-04-01 2010-04-01 false What is an IRR Transportation Facilities Maintenance...

A microchannel plate X-ray multiplier with rising-time less than 170 ps