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Sample records for rand review volume

  1. Rand Corporation

    Science.gov (United States)

    ... Jobs at RAND Media Resources Congressional Resources Doing Business with RAND Supporting RAND Educational Opportunities Alumni Association Follow RAND Corporation on Facebook RAND Corporation on Twitter RAND Corporation on LinkedIn ...

  2. RAND-Based Formulations for Isothermal Multiphase Flash

    DEFF Research Database (Denmark)

    Paterson, Duncan; Michelsen, Michael L.; Stenby, Erling H.

    2018-01-01

    Two algorithms are proposed for isothermal multiphase flash. These are referred to as modified RAND and vol-RAND. The former uses the chemical potentials and molar-phase amounts as the iteration variables, while the latter uses chemical potentials and phase volumes to cosolve a pressure...

  3. Sexual Assault and Sexual Harassment in the U.S. Military: Annex to Volume 3. Tabular Results from the 2014 RAND Military Workplace Study for Coast Guard Service Members

    Science.gov (United States)

    2015-01-01

    95 B.2. Percentage of members who experienced sexual quid pro quo in the past year...Volume 3 B.2. Percentage of members who experienced sexual quid pro quo in the past year Table B.2 Percentage of members who experienced sexual quid ... SEXUAL ASSAULT AND SEXUAL HARASSMENT IN THE U.S. MILITARY Annex to Volume 3. Tabular Results from the 2014 RAND Military Workplace Study for

  4. Sexual Assault and Sexual Harassment in the U.S. Military: Annex to Volume 2. Tabular Results from the 2014 RAND Military Workplace Study for Department of Defense Service Members

    Science.gov (United States)

    2015-01-01

    Workplace role of the offender(s) among men who experienced sexual harassment or gender discrimination in the past year, by service... Sexual Assault and Sexual Harassment in the U.S. Military: Annex to Volume 2 Table B.10.f Workplace role of the offender(s) among men who experienced... SEXUAL ASSAULT AND SEXUAL HARASSMENT IN THE U.S. MILITARY Annex to Volume 2. Tabular Results from the 2014 RAND Military Workplace

  5. Early history and reactivation of the rand thrust, southern California

    Science.gov (United States)

    Postlethwaite, Clay E.; Jacobson, Carl E.

    The Rand thrust of the Rand Mountains in the northwestern Mojave Desert separates an upper plate of quartz monzonite and quartzofeldspathic to amphibolitic gneiss from a lower plate of metagraywacke and mafic schist (Rand Schist). The Rand thrust is considered part of the regionally extensive Vincent/Chocolate Mountain thrust system, which is commonly believed to represent a Late Cretaceous subduction zone. The initial direction of dip and sense of movement along the Vincent/Chocolate Mountain thrust are controversial. Microfabrics of mylonites and quartzites from the Rand Mountains were analyzed in an attempt to determine transport direction for this region, but the results are ambiguous. In addition, the southwestern portion of the Rand thrust was found to have been reactivated as a low-angle normal fault after subduction. Reactivation might have occurred shortly after subduction, in which case it could account for the preservation of high-pressure mineral assemblages in the Rand Schist, or it could be related to mid-Tertiary extension in the western United States. In either event, the reactivation might be responsible for the complicated nature of the microfabrics. The Rand Schist exhibits an inverted metamorphic zonation. Isograds in the schist are not significantly truncated by the reactivated segment of the Rand thrust. This indicates that other segments of the Vincent/Chocolate Mountain thrust should be re-evaluated for the possibility of late movement, even if they show an apparently undisturbed inverted metamorphic zonation.

  6. The Asymmetric Effect in the Volatility of the South African Rand

    Directory of Open Access Journals (Sweden)

    Idoko Ahmed Itodo

    2017-09-01

    Full Text Available This study investigates the behaviour of the volatility in the South African Rand/USD exchange rate and its impact on the value of the Rand between 2001 and 2017. The key objectives were to assess the impact of its volatility on its market value, and determine the presence of asymmetric effect in the times path of the volatility, resulting from shocks to its market value. From the estimates of our EGARCH-M (1,1 model, we found the value of the Rand to respond negatively to volatility it is time path, suggesting that the Rand appreciates more in value under conditions of less tranquillity. In addition, we found evidence of asymmetric effect, of shocks to the conditional mean, in the conditional variance of the Rand. The asymmetric effect is such that negative shocks to the conditional mean, which causes the Rand to appreciate, have more impact on next point volatility in the Rand than positive shocks of the same magnitude, which causes depreciation in its value.

  7. Evaluación del uso apropiado de procedimientos sanitarios mediante el método RAND: revisión de su aplicación en la literatura biomédica (1999-2004 Review of the utilization of the RAND appropriateness method in the biomedical literature (1999-2004

    Directory of Open Access Journals (Sweden)

    Nerea González

    2009-06-01

    Full Text Available Objetivos: Identificar y describir los estudios de evaluación del uso apropiado de procedimientos sanitarios en los cuales se haya empleado el método RAND/UCLA. Se trata de una técnica de consenso con varias fases para el desarrollo de criterios de uso apropiado. Métodos: La búsqueda bibliográfica se realizó en 2005, consultando las bases de datos OVID-Medline, ISI Web of Knowledge, Índice Médico Español y Highwire. Se seleccionaron los artículos publicados entre 1999 y 2004 que tuviesen las palabras clave «appropriateness», «utilization review» y «physician practice patterns». Se incluyeron los estudios en que se hubiese aplicado el método RAND y se excluyeron aquellos cuya metodología no estuviese suficientemente explicada. De cada artículo se extrajo información sobre el procedimiento estudiado, el lugar y el año de publicación, y las características de la revista. Resultados y discusión: Se identificaron 5.092 referencias y se seleccionaron 205. Algo más de la mitad analizaban procedimientos quirúrgicos o médicos, mientras que el 16,5% se centraba en la evaluación de la calidad asistencial. Más del 50% fueron trabajos publicados en revistas de salud pública, medicina general, y gastroenterología y hepatología. La media del factor de impacto era de 4,07. El 25,4% de los artículos habían sido publicados en 1999. Conclusiones y perspectivas: El método RAND se sigue utilizando ampliamente. Los criterios de uso apropiado pueden emplearse para la revisión de la utilización de procedimientos, como base para elaborar guías o como apoyo para la toma de decisiones. Estas herramientas han de ser sometidas a revisiones para obtener resultados cada vez más válidos y fiables.Objectives: To identify and describe studies using the RAND/UCLA method to evaluate the appropriateness of health procedures. This method is a consensus technique that involves several phases to develop appropriateness criteria. Methods: We

  8. Calculation of Multiphase Chemical Equilibrium by the Modified RAND Method

    DEFF Research Database (Denmark)

    Tsanas, Christos; Stenby, Erling Halfdan; Yan, Wei

    2017-01-01

    method. The modified RAND extends the classical RAND method from single-phase chemical reaction equilibrium of ideal systems to multiphase chemical equilibrium of nonideal systems. All components in all phases are treated in the same manner and the system Gibbs energy can be used to monitor convergence....... This is the first time that modified RAND was applied to multiphase chemical equilibrium systems. The combined algorithm was tested using nine examples covering vapor–liquid (VLE) and vapor–liquid–liquid equilibria (VLLE) of ideal and nonideal reaction systems. Successive substitution provided good initial......A robust and efficient algorithm for simultaneous chemical and phase equilibrium calculations is proposed. It combines two individual nonstoichiometric solving procedures: a nested-loop method with successive substitution for the first steps and final convergence with the second-order modified RAND...

  9. Ayn Rand phenomenon in contemporary social and ethical problems

    Directory of Open Access Journals (Sweden)

    M. I. Korobko

    2014-03-01

    Full Text Available This paper attempts to give a general outline of the phenomenon of well­known American writer and philosopher Ayn Rand in contemporary social and ethical space. Application to the research of life, literary and philosophical heritage of the writer makes it possible to assess its impact on the current situation in politics and philosophy. Review of Ayn Rand’s artistic positions confirms her role as a landmark figure, who represented at that time the actual socio­cultural request of active man in contemporary philosophy and politics, “putting down” in literary form complex of philosophical questions to the level of the ordinary man. Ayn Rand is the focus of the social practices in which she was formed, lived and worked. The ideas of almost all philosophical subjects are presented in her works in a simple way, but they are fundamentally different from conventional notions of ethics, politics and philosophy in general, even the ideas of philosophers, whom she honored, such as Aristotle. That’s why modern philosophers are interested in studying her works now. After all, still there has no comprehensive academic analysis of her philosophical and scientific works of art.

  10. Reading "The Fountainhead": The Missing Self in Ayn Rand's Ethical Individualism

    Science.gov (United States)

    Fand, Roxanne J.

    2009-01-01

    Ayn Rand's novel "The Fountainhead" can be a useful text in an undergraduate English class, helping students think through issues of individualism. Rand's own concept of the self, however, ignores its social dimensions. (Contains 7 notes.)

  11. Deterrence from Cold War to Long War: Lessons from Six Decades of RAND Research

    Science.gov (United States)

    2008-01-01

    that humor was not absent from RAND analysis, gave the first system in this paper the code-name Lucy, making reference to the Beatles ’ song “Lucy in...document was made available from www.rand.org as a public service of the RAND Corporation. 6Jump down to document THE ARTS CHILD POLICY CIVIL JUSTICE...TECHNOLOGY SUBSTANCE ABUSE TERRORISM AND HOMELAND SECURITY TRANSPORTATION AND INFRASTRUCTURE WORKFORCE AND WORKPLACE The RAND Corporation is a nonprofit

  12. 77 FR 6156 - Rand Capital Corporation, et al.; Notice of Application

    Science.gov (United States)

    2012-02-07

    ... venture capital investments in small, early-stage and developing enterprises. Rand's principal objective... Capital Corporation, et al.; Notice of Application February 1, 2012. AGENCY: Securities and Exchange... Act'') granting an exemption from section 13(a) of the Exchange Act. Applicants: Rand Capital...

  13. Rand Corporation Mean Monthly Global Snow Depth

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — All available monthly snow depth climatologies were integrated by the Rand Corporation, in the early 1980s, into one global (excluding Africa and South America)...

  14. Rethinking ASGISA and the rand exchange rate

    Directory of Open Access Journals (Sweden)

    Willem H Boshoff

    2012-05-01

    Full Text Available Abstract: The ASGISA policy document identifies the exchange rate as one of the factors constraining accelerated growth in South Africa. This note argues that currency developments do not translate into business cycle movements in the aggregate economy, and that a weaker exchange rate is less likely to boost either foreign investment or export performance in the face of regulatory uncertainty. The South African government has recently launched the Accelerated and Shared Growth Initiative (ASGISA aimed at raising the long-term growth path of the economy. The plan identifies several so-called “binding constraints” that are considered to be inhibiting the economy from rising to more elevated levels of economic growth. One such “constraint”, according to the ASGISA policy document, is the “volatility and level of the currency” (Republic of South Africa, 2006. By including this issue, policymakers have signalled that fluctuations in the Rand are considered significant to broader economic fluctuations in South Africa. This research note questions such a conviction by offering evidence that currency fluctuations are not mirrored in the South African business cycle. Nonetheless, proponents may argue that a weaker Rand will stimulate particular sectors, mostly those that are export-oriented, while it will boost Foreign Direct Investment (FDI. However, this note argues further that a weaker Rand is less likely to generate sustainable improvement in either export-oriented industries or FDI in the absence of other reforms. The following sections consider these two issues in sequence.

  15. The RAND Health Insurance Experiment, Three Decades Later*

    Science.gov (United States)

    Aron-Dine, Aviva; Einav, Liran; Finkelstein, Amy

    2013-01-01

    We re-present and re-examine the analysis from the famous RAND Health Insurance Experiment from the 1970s on the impact of consumer cost sharing in health insurance on medical spending. We begin by summarizing the experiment and its core findings in a manner that would be standard in the current age. We then examine potential threats to the validity of a causal interpretation of the experimental treatment effects stemming from different study participation and differential reporting of outcomes across treatment arms. Finally, we re-consider the famous RAND estimate that the elasticity of medical spending with respect to its out-of-pocket price is −0.2, emphasizing the challenges associated with summarizing the experimental treatment effects from non-linear health insurance contracts using a single price elasticity. PMID:24610973

  16. Ayn Rand's fiction and the shaping of modern american individualism

    OpenAIRE

    Stanforth, Daniel Phillip

    2018-01-01

    A lo largo de la historia, han surgido varios movimientos políticos y filosóficos, pero la gran mayoría no han perdurado. Sin embargo, algunos, como la democracia o el comunismo se popularizan y afectan al mundo entero. Aquí en los Estados Unidos, la nueva filosofía quizás más desafiante e inusual ha sido formada por la novelista, Ayn Rand. El punto de vista de Rand sigue siendo relativamente desconocido en América, pero si se arraigase, revolucionaría nuestras vidas. Esta cita fue la int...

  17. The RAND Consensus Study for Primary Open-Angle Glaucoma in Latin America

    OpenAIRE

    Paulo E.C. Dantas

    2013-01-01

    Abstract Purpose: To report the results of a Latin American (LA) consensus panel regarding the diagnosis and management of primary open angle glaucoma, and to compare these results with those from a similar panel in the United States (US). Design: A RAND-like appropriateness methodology was used to assess glaucoma practice in LA. Methods: The 148 polling statements created for the RAND- like analysis in the US and 10 additional statements specific to glaucoma care in LA were presented to a pa...

  18. Organizing complexity: the hopeful dreams and harsh realities of interdisciplinary collaboration at the rand corporation in the early cold war.

    Science.gov (United States)

    Bessner, Daniel

    2015-01-01

    Historians argue that in the early Cold War an interdisciplinary research culture defined the RAND Corporation. However, a significant epistemological gap divided the members of RAND's Social Science Division (SSD) from the rest of the organization. While the social scientists used qualitative methods, most RAND researchers embraced quantified approaches and derided the social sciences as unscientific. This encouraged RAND's social scientists to develop a political-military simulation that embraced everything-politics, culture, and psychology-that RAND's other analysts largely ignored. Yet the fact that the SSD embraced gaming, a heuristic practiced throughout RAND, suggests that the political simulation was nonetheless inspired by social scientists' engagement with their colleagues. This indicates that the concept of interdisciplinarity should move beyond its implication of collaboration to incorporate instances in which research agendas are defined against but also shaped by colleagues in other disciplines. Such a rethinking of the term may make it possible to trace how varieties of interdisciplinary interaction historically informed knowledge production. © 2014 Wiley Periodicals, Inc.

  19. RandAgiamo™, a Pilot Project Increasing Adoptability of Shelter Dogs in the Umbria Region (Italy)

    Science.gov (United States)

    Menchetti, Laura; Mancini, Stefania; Catalani, Maria Chiara; Boccini, Beatrice; Diverio, Silvana

    2015-01-01

    Simple Summary In Italy, dog shelters are overcrowded because the rate of dog adoption is lower than that of abandonment. A project called “RandAgiamo” was implemented in a rescue shelter in central Italy. RandAgiamo provides training, socialization and advertising of adult shelter dogs. Official data of the Umbria regional health authorities from the year 2014 showed a higher rate of adoption in shelters involved in the project. RandAgiamo dogs had triple odds of being adopted compared to others housed in shelters of the same province. The increase in adoption rate can be beneficial for both dog welfare and shelter management. Abstract Current Italian legislation does not permit euthanasia of dogs, unless they are ill or dangerous. Despite good intentions and ethical benefits, this “no-kill policy” has caused a progressive overpopulation of dogs in shelters, due to abandonment rates being higher than adoption rates. Shelter overcrowding has negative implications for dog welfare and increases public costs. The aim of this paper is to describe the pilot project “RandAgiamo” implemented in a rescue shelter in the Umbria Region and to evaluate its effectiveness on the rate of dog adoption using official data. RandAgiamo aimed to increase adult shelter dogs’ adoptability by a standard training and socialization programme. It also promoted dogs’ visibility by publicizing them through social media and participation in events. We analysed the official data of the Umbria regional health authorities regarding dog shelters of the Perugia province of the year 2014. In the RandAgiamo shelter, the dog adoption rate was 27.5% higher than that of dogs housed in other shelters located in the same geographical area (p dogs’ welfare, owner satisfaction, shelter management, and public perception of shelter dogs. However, staff were required to provide dog training and related activities. PMID:26479385

  20. Animatsiooni vastu ei saa ükski / Mikk Rand

    Index Scriptorium Estoniae

    Rand, Mikk, 1970-

    1998-01-01

    21.5. esilinastuvad kinos "Sõprus" 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer

  1. Rand Review, Volume 25, Number 1, Spring 2001

    National Research Council Canada - National Science Library

    Popper, Steven W

    2001-01-01

    .... The cover story outlines a global agenda for the United States. Painstakingly bipartisan in its derivation, the story advocates "selective global leadership" in foreign and defense policy, combined with "strengthened and revitalized alliances...

  2. RAND-like appropriateness methodology consensus for primary open-angle glaucoma in Latin America.

    Science.gov (United States)

    Lerner, S Fabian; Singh, Kuldev; Susanna, Remo; Wilson, M Roy; Lee, Brian L; Maul, Eugenio

    2012-09-01

    To report the results of a Latin American consensus panel regarding the diagnosis and management of primary open-angle glaucoma and to compare these results with those from a similar panel in the United States. A RAND-like (Research and Development) appropriateness methodology was used to assess glaucoma practice in Latin America. The 148 polling statements created for the RAND- like analysis in the United States and 10 additional statements specific to glaucoma care in Latin America were presented to a panel of Latin American glaucoma experts. Panelists were polled in private using the RAND- like methodology before and after the panel meeting. Consensus agreement or disagreement among Latin American experts was reached for 51.3% of statements before the meeting and increased to 66.5% in the private, anonymous meeting after polling (79.0% agreement, 21.0% disagreement). Although there was a high degree of concordance (111 of 148 statements; 75%) between the results of this Latin American panel and the United States panel, there were some notable exceptions relating to diagnostic and therapeutic decision making. This RAND-like consensus methodology provides a perspective of how Latin American glaucoma practitioners view many aspects of glaucoma and compares these results with those obtained using a similar methodology from practitioners in the United States. These findings may be helpful to ophthalmologists providing glaucoma care in Latin America and in other regions of the world. Copyright © 2012 Elsevier Inc. All rights reserved.

  3. Hydrogeological assessment of Acid mine Drainage impacts in the West Rand Basin, Gauteng Province

    CSIR Research Space (South Africa)

    Hobbs, PJ

    2007-08-01

    Full Text Available HYDROGEOLOGICAL ASSESSMENT OF ACID MINE DRAINAGE IMPACTS IN THE WEST RAND BASIN, GAUTENG PROVINCE Principal Author PJ Hobbs (Pr.Sci.Nat.) Co-author JE Cobbing (Pr.Sci.Nat.) August 2007 Report prepared for CSIR / THRIP Document... it is published. A Hydrogeological Assessment of Acid Mine Drainage Report No. Impacts in the West Rand Basin, Gauteng Province CSIR/NRE/WR/ER/2007/0097/C CSIR Natural Resources and the Environment (i) The “Lodge” spring rising...

  4. RandAgiamo™, a Pilot Project Increasing Adoptability of Shelter Dogs in the Umbria Region (Italy).

    Science.gov (United States)

    Menchetti, Laura; Mancini, Stefania; Catalani, Maria Chiara; Boccini, Beatrice; Diverio, Silvana

    2015-08-14

    Current Italian legislation does not permit euthanasia of dogs, unless they are ill or dangerous. Despite good intentions and ethical benefits, this 'no-kill policy' has caused a progressive overpopulation of dogs in shelters, due to abandonment rates being higher than adoption rates. Shelter overcrowding has negative implications for dog welfare and increases public costs. The aim of this paper is to describe the pilot project "RandAgiamo" implemented in a rescue shelter in the Umbria Region and to evaluate its effectiveness on the rate of dog adoption using official data. RandAgiamo aimed to increase adult shelter dogs' adoptability by a standard training and socialization programme. It also promoted dogs' visibility by publicizing them through social media and participation in events. We analysed the official data of the Umbria regional health authorities regarding dog shelters of the Perugia province of the year 2014. In the RandAgiamo shelter, the dog adoption rate was 27.5% higher than that of dogs housed in other shelters located in the same geographical area (P < 0.001). The RandAgiamo project could be beneficial for the dogs' welfare, owner satisfaction, shelter management, and public perception of shelter dogs. However, staff were required to provide dog training and related activities.

  5. RandAgiamo™, a Pilot Project Increasing Adoptability of Shelter Dogs in the Umbria Region (Italy

    Directory of Open Access Journals (Sweden)

    Laura Menchetti

    2015-08-01

    Full Text Available Current Italian legislation does not permit euthanasia of dogs, unless they are ill or dangerous. Despite good intentions and ethical benefits, this ‘no-kill policy’ has caused a progressive overpopulation of dogs in shelters, due to abandonment rates being higher than adoption rates. Shelter overcrowding has negative implications for dog welfare and increases public costs. The aim of this paper is to describe the pilot project “RandAgiamo” implemented in a rescue shelter in the Umbria Region and to evaluate its effectiveness on the rate of dog adoption using official data. RandAgiamo aimed to increase adult shelter dogs’ adoptability by a standard training and socialization programme. It also promoted dogs’ visibility by publicizing them through social media and participation in events. We analysed the official data of the Umbria regional health authorities regarding dog shelters of the Perugia province of the year 2014. In the RandAgiamo shelter, the dog adoption rate was 27.5% higher than that of dogs housed in other shelters located in the same geographical area (P < 0.001. The RandAgiamo project could be beneficial for the dogs’ welfare, owner satisfaction, shelter management, and public perception of shelter dogs. However, staff were required to provide dog training and related activities.

  6. Değişik Randımanlı Unlarda Tiyamin, Riboflavin ve Demir Miktarı

    Directory of Open Access Journals (Sweden)

    Recai Ercan

    2015-02-01

    Full Text Available Undaki besin öğesi miktarı, randımana bağlı olarak değişmektedir. Değişik randımanlı unlardaki doğal besin öğesi miktarı, gıda zenginleştirme uygulaması açısından da önem taşımaktadır. Randımana bağlı olarak ticari unlar 6 tipe ayrılmaktadır. Değişik tip unlardaki riboflavin, tiyamin ve demir miktarını belirlemek amacıyla farklı 10 değirmenden sağlanan un örnekleri analiz edilmiştir. Bulgulara göre ekmek hammaddesi olarak kullanılan Tip 4 unlarında (%80 randıman, tiyamin miktarı 1.15-2.08 mg/kg (ortalama 1.72 mg/kg, riboflavin miktarı 0.65-0.90 mg/kg (ortalama 0.81 mg/kg, demir miktarı 12.0-29.6 mg/kg (ortalama 16.77 mg/kg arasında değişmektedir.

  7. Perspectives for RandD in Bioenergy in the Baltic States

    Energy Technology Data Exchange (ETDEWEB)

    Holmberg, Rurik (Technopolis Group, Stockholm (Sweden) )

    2009-11-15

    This study has identified two almost contradictory trends regarding bioenergy in the Baltic States. On the one hand, RandD performed in bioenergy in the Baltic States is rather limited. This might be somewhat surprising, because on the other hand various forms of bioenergy are either already used on a large scale or are widely assumed to become important in the near future. Bioenergy is explicitly recognized in various policy plans as an important component of the energy system in all the Baltic States. Thus the limited RandD efforts raise a number of questions, which probably lack unequivocal answers, but which would be important to discuss in the Baltic States. In all three Baltic States, bioenergy has a major potential. The present trend with boiler houses using biomass in a district heating systems commenced in the 1990s with significant foreign support. Technology was mainly imported, but in some cases local producers have drawn upon these experiences and become producers in their own right. The result has been that the Baltic States have relatively well developed bioenergy technology in use in district heating. But perhaps more importantly, there is know-how and experience in the Baltic States from the use of bioenergy, which however needs to be constantly upgraded. Regarding interest groups, one question raised by some interviewees was whether the natural gas industry with Russian Gazprom as the key player has a bigger say in the energy policy of the Baltic States than officially admitted. Although this issue remains speculative, the question as such is justified and should not be omitted from the discussion. The interest groups behind bioenergy are relatively weak, at least in comparison with other interest groups in the energy sector. As long as the farmers' organizations are not unambiguously behind bioenergy, the political support for investments in developing new technology is likely to remain lukewarm. Cooperation between the Baltic States in

  8. Living on the edge: timing of Rand Flora disjunctions congruent with ongoing aridification in Africa.

    Science.gov (United States)

    Pokorny, Lisa; Riina, Ricarda; Mairal, Mario; Meseguer, Andrea S; Culshaw, Victoria; Cendoya, Jon; Serrano, Miguel; Carbajal, Rodrigo; Ortiz, Santiago; Heuertz, Myriam; Sanmartín, Isabel

    2015-01-01

    The Rand Flora is a well-known floristic pattern in which unrelated plant lineages show similar disjunct distributions in the continental margins of Africa and adjacent islands-Macaronesia-northwest Africa, Horn of Africa-Southern Arabia, Eastern Africa, and Southern Africa. These lineages are now separated by environmental barriers such as the arid regions of the Sahara and Kalahari Deserts or the tropical lowlands of Central Africa. Alternative explanations for the Rand Flora pattern range from vicariance and climate-driven extinction of a widespread pan-African flora to independent dispersal events and speciation in situ. To provide a temporal framework for this pattern, we used published data from nuclear and chloroplast DNA to estimate the age of disjunction of 17 lineages that span 12 families and nine orders of angiosperms. We further used these estimates to infer diversification rates for Rand Flora disjunct clades in relation to their higher-level encompassing lineages. Our results indicate that most disjunctions fall within the Miocene and Pliocene periods, coinciding with the onset of a major aridification trend, still ongoing, in Africa. Age of disjunctions seemed to be related to the climatic affinities of each Rand Flora lineage, with sub-humid taxa dated earlier (e.g., Sideroxylon) and those with more xeric affinities (e.g., Campylanthus) diverging later. We did not find support for significant decreases in diversification rates in most groups, with the exception of older subtropical lineages (e.g., Sideroxylon, Hypericum, or Canarina), but some lineages (e.g., Cicer, Campylanthus) showed a long temporal gap between stem and crown ages, suggestive of extinction. In all, the Rand Flora pattern seems to fit the definition of biogeographic pseudocongruence, with the pattern arising at different times in response to the increasing aridity of the African continent, with interspersed periods of humidity allowing range expansions.

  9. Le commerce des sels de Guérande (xviie-xviiie siècles)

    OpenAIRE

    Buron, Gildas

    2015-01-01

    Depuis les travaux de Michel Mollat, Henri Touchard, Jean Tanguy et Jean Meyer touchant au sel et aux marais salants du pays de Guérande, l’historien en est resté à l’idée que la production salicole guérandaise n’avait connu, aux Temps modernes, de débouchés que régionaux, vers la Bretagne intérieure par le biais de la troque effectuée par les gens du marais. L’enquête en cours montre que les sels de Guérande, certes peu présents dans le grand commerce international du sel de la Baie du xive ...

  10. Naval Law Review. Volume 60, 2010

    Science.gov (United States)

    2010-01-01

    that the Rand, a towboat restaurant , was not a vessel because its engines did not work, requiring it to be towed. The Templeton court held that...officers will not modify their behaviour unless they believe it is in their personal interest.”20 The Handbook lists promotions, pay increases, and...to our consumers . Bacevich argues that, despite what we may think of our country, we have always been a country of expansion. When the borders

  11. Sexual Assault and Sexual Harassment in the U.S. Military: Highlights from the 2014 RAND Military Workplace Study

    Science.gov (United States)

    2015-01-01

    assault, sexual harassment , and gender discrimination in the military. The resulting study, the RAND Military Workplace Study (RMWS), invited close to...members are highlighted in this brief. Sexual Assault and Sexual Harassment in the U.S. Military HigHligHts from tHe 2014 rAND militAry WorkplAce stuDy...significantly higher rates than men : 22 percent of women and 7 percent of men experienced sexual harassment in the past year. In addition, we estimate

  12. NPR hazards review: (Phase 1, Production only appendixes). Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    Miller, N.R.; Trumble, R.E.

    1962-08-15

    The NPR Hazards Review is being issued in a series of volumes. Volume 1, which has already been published, was of the nature of an expanded summary. It included the results of hazards analyses with some explanatory material to put the results in context. Volume 2 presents results of reviews made after the preparation of Volume 1. It also contains supporting material and details not included in Volume 1. Volumes 1 and 2 together provide a nearly complete ``Design Hazards Review of the NPR.`` However, certain remaining problems still exist and are to be the subject of a continuing R&D program. These problems and programs are discussed in Appendix H. Neither Volume 1 nor Volume 2 treat operational aspects of reactor hazards in detail. This area of concern will be the primary subject of a third volume of the NPR Hazards Review. This third volume, to be prepared and issued at a later date, may also contain information supplementing Volumes 1 and 2.

  13. Unearthing a hidden treasure: 60 years of karst research in the Far West Rand, South Africa

    Directory of Open Access Journals (Sweden)

    Aljoscha Schrader

    2015-05-01

    Full Text Available Karstified dolomitic formations situated in the Far West Rand goldfield of the Witwatersrand Basin constitute a significant groundwater resource in semi?arid South Africa and would be of strategic importance for alleviating the increasing water stress in nearby metropolitan areas. The deep?level gold mines operating below the dolomites have suffered from large volumes of dolomitic groundwater flowing into the mine voids, rendering mining both expensive and hazardous. In order to secure safe and economical mining, the overlying dolomites were dewatered. Here we review research over 60 years, conducted in three of the four major dolomitic compartments affected by dewatering. After more than six decades of research, these aquifers are arguably the most investigated karst systems in South Africa, and possibly worldwide. The data generated are, in many respects, unique, as many measurements can never be repeated, covering stochastic events such as a major water inrush into mine workings and some of the most catastrophic sinkhole developments ever recorded. Given the potential value for improving the understanding of general and local karst hydrogeology, our main goal for this paper is to alert the scientific community to the existence of this resource of mostly unpublished data and research. A no less important aim is to support a systematic collation of these studies which are in danger of being irretrievably lost as mines increasingly close down. Ecological and economic impacts of the flooding of mines in and around Johannesburg emphasise the lack of reliable historical mine data to optimally address the matter. We provide the first comprehensive, yet not exhaustive, overview on the existing studies, briefly discussing scientific content as well as obstacles for utilising the scattered, and often non?peer reviewed, information sources.

  14. South Africa and United States stock prices and the Rand/Dollar exchange rate

    Directory of Open Access Journals (Sweden)

    Matthew Ocran

    2010-09-01

    Full Text Available This paper seeks to examine the dynamic causal relations between the two major financial assets, stock prices of the US and South Africa and the rand/US$ exchange rate. The study uses a mixed bag of time series approaches such as cointegration, Granger causality, impulse response functions and forecasting error variance decompositions.  The paper identifies a bi-directional causality from the Standard & Poor’s 500 stock price index to the rand/US$ exchange rate in the Granger sense. It was also found that the Standard & Poor’s stock price index accounts for a significant portion of the variations in the Johannesburg Stock Exchange’s All Share index. Thus, while causality in the Granger sense could not be established for the relationship between the price indices of the two stock exchanges it can argued that there is some relationship between them. The results of the study have implications for both business and Government.

  15. Human-system interface design review guideline -- Reviewer`s checklist: Final report. Revision 1, Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-06-01

    NUREG-0700, Revision 1, provides human factors engineering (HFE) guidance to the US Nuclear Regulatory Commission staff for its: (1) review of the human system interface (HSI) design submittals prepared by licensees or applications for a license or design certification of commercial nuclear power plants, and (2) performance of HSI reviews that could be undertaken as part of an inspection or other type of regulatory review involving HSI design or incidents involving human performance. The guidance consists of a review process and HFE guidelines. The document describes those aspects of the HSI design review process that are important to the identification and resolution of human engineering discrepancies that could adversely affect plant safety. Guidance is provided that could be used by the staff to review an applicant`s HSI design review process or to guide the development of an HSI design review plan, e.g., as part of an inspection activity. The document also provides detailed HFE guidelines for the assessment of HSI design implementations. NUREG-0700, Revision 1, consists of three stand-alone volumes. Volume 2 is a complete set of the guidelines contained in Volume 1, Part 2, but in a checklist format that can be used by reviewers to assemble sets of individual guidelines for use in specific design reviews. The checklist provides space for reviewers to enter guidelines evaluations and comments.

  16. Review of Random Phase Encoding in Volume Holographic Storage

    Directory of Open Access Journals (Sweden)

    Wei-Chia Su

    2012-09-01

    Full Text Available Random phase encoding is a unique technique for volume hologram which can be applied to various applications such as holographic multiplexing storage, image encryption, and optical sensing. In this review article, we first review and discuss diffraction selectivity of random phase encoding in volume holograms, which is the most important parameter related to multiplexing capacity of volume holographic storage. We then review an image encryption system based on random phase encoding. The alignment of phase key for decryption of the encoded image stored in holographic memory is analyzed and discussed. In the latter part of the review, an all-optical sensing system implemented by random phase encoding and holographic interconnection is presented.

  17. Investigation of DBMS for Use in a Research Environment. Rand Paper Series 7002.

    Science.gov (United States)

    Rosenfeld, Pilar N.

    This investigation of the use of database management systems (DBMS) in a research environment used the Rand Corporation as a case study. After a general introduction in section 1, eight sections present the major components of the study. Section 2 contains an overview of DBMS terminology and concepts, followed in section 3 by a general dsecription…

  18. How does sagittal imbalance affect the appropriateness of surgical indications and selection of procedure in the treatment of degenerative scoliosis? Findings from the RAND/UCLA Appropriate Use Criteria study.

    Science.gov (United States)

    Daubs, Michael D; Brara, Harsimran S; Raaen, Laura B; Chen, Peggy Guey-Chi; Anderson, Ashaunta T; Asch, Steven M; Nuckols, Teryl K

    2018-05-01

    Degenerative lumbar scoliosis (DLS) is often associated with sagittal imbalance, which may affect patients' health outcomes before and after surgery. The appropriateness of surgery and preferred operative approaches has not been examined in detail for patients with DLS and sagittal imbalance. The goals of this article were to describe what is currently known about the relationship between sagittal imbalance and health outcomes among patients with DLS and to determine how indications for surgery in patients with DLS differ when sagittal imbalance is present. This study included a literature review and an expert panel using the RAND/University of California at Los Angeles (UCLA) Appropriateness Method. To develop appropriate use criteria for DLS, researchers at the RAND Corporation recently employed the RAND/UCLA Appropriateness Method, which involves a systematic review of the literature and multidisciplinary expert panel process. Experts reviewed a synopsis of published literature and rated the appropriateness of five common operative approaches for 260 different clinical scenarios. In the present work, we updated the literature review and compared panelists' ratings in scenarios where imbalance was present versus absent. This work was funded by the Collaborative Spine Research Foundation, a group of surgical specialty societies and device manufacturers. On the basis of 13 eligible studies that examined sagittal imbalance and outcomes in patients with DLS, imbalance was associated with worse functional status in the absence of surgery and worse symptoms and complications postoperatively. Panelists' ratings demonstrated a consistent pattern across the diverse clinical scenarios. In general, when imbalance was present, surgery was more likely to be appropriate or necessary, including in some situations where surgery would otherwise be inappropriate. For patients with moderate to severe symptoms and imbalance, a deformity correction procedure was usually appropriate

  19. Designing an Effective Prevention Program: Principles Underlying the Rand Smoking and Drug Prevention Experiment.

    Science.gov (United States)

    Ellickson, Phyllis L.

    This paper describes the Project ALERT program (Adolescent Learning Experiences in Resistance Training) which was established by the Rand Corporation to prevent smoking and drug use among seventh graders. The program is based on the social influence model of drug use initiation. Curriculum features are described including motivation to resist and…

  20. Ayn Rand: To be Selfish or Not to be Selfish--That is the Question

    Science.gov (United States)

    Doctor, Tyrus L.; Kritsonis, William Allan

    2009-01-01

    Ayn Rand's "The Virtue of Selfishness" (1961) is comprised of a philosophy that defies the entire premise of what our education system is and shall be built upon. The "Objectivist" perspective has depicted a clear distinction between the "Have's" and the "Have Not's" or the Bourgeoisie and Proletariat. The "Objectivist" perspective believes that…

  1. A simulation based approach to optimize inventory replenishment with RAND algorithm: An extended study of corrected demand using Holt's method for textile industry

    Science.gov (United States)

    Morshed, Mohammad Sarwar; Kamal, Mostafa Mashnoon; Khan, Somaiya Islam

    2016-07-01

    Inventory has been a major concern in supply chain and numerous researches have been done lately on inventory control which brought forth a number of methods that efficiently manage inventory and related overheads by reducing cost of replenishment. This research is aimed towards providing a better replenishment policy in case of multi-product, single supplier situations for chemical raw materials of textile industries in Bangladesh. It is assumed that industries currently pursue individual replenishment system. The purpose is to find out the optimum ideal cycle time and individual replenishment cycle time of each product for replenishment that will cause lowest annual holding and ordering cost, and also find the optimum ordering quantity. In this paper indirect grouping strategy has been used. It is suggested that indirect grouping Strategy outperforms direct grouping strategy when major cost is high. An algorithm by Kaspi and Rosenblatt (1991) called RAND is exercised for its simplicity and ease of application. RAND provides an ideal cycle time (T) for replenishment and integer multiplier (ki) for individual items. Thus the replenishment cycle time for each product is found as T×ki. Firstly, based on data, a comparison between currently prevailing (individual) process and RAND is provided that uses the actual demands which presents 49% improvement in total cost of replenishment. Secondly, discrepancies in demand is corrected by using Holt's method. However, demands can only be forecasted one or two months into the future because of the demand pattern of the industry under consideration. Evidently, application of RAND with corrected demand display even greater improvement. The results of this study demonstrates that cost of replenishment can be significantly reduced by applying RAND algorithm and exponential smoothing models.

  2. Breckinridge Project, initial effort. Report XI, Volume V. Critical review of the design basis. [Critical review

    Energy Technology Data Exchange (ETDEWEB)

    None

    1982-01-01

    Report XI, Technical Audit, is a compendium of research material used during the Initial Effort in making engineering comparisons and decisions. Volumes 4 and 5 of Report XI present those studies which provide a Critical Review of the Design Basis. The Critical Review Report, prepared by Intercontinental Econergy Associates, Inc., summarizes findings from an extensive review of the data base for the H-Coal process design. Volume 4 presents this review and assessment, and includes supporting material; specifically, Design Data Tabulation (Appendix A), Process Flow Sheets (Appendix B), and References (Appendix C). Volume 5 is a continuation of the references of Appendix C. Studies of a proprietary nature are noted and referenced, but are not included in these volumes. They are included in the Limited Access versions of these reports and may be reviewed by properly cleared personnel in the offices of Ashland Synthetic Fuels, Inc.

  3. Extension of modified RAND to multiphase flash specifications based on state functions other than (T,P)

    DEFF Research Database (Denmark)

    Paterson, Duncan; Michelsen, Michael Locht; Yan, Wei

    2017-01-01

    The recently proposed modified RAND formulation is extended from isothermal multiphase flash to several other state function based flash specifications. The obtained general formulation is applicable to chemical equilibrium although this study is focused on flash with only phase equilibrium. It i...

  4. Development and validation of Australian aphasia rehabilitation best practice statements using the RAND/UCLA appropriateness method

    Science.gov (United States)

    Power, Emma; Thomas, Emma; Worrall, Linda; Rose, Miranda; Togher, Leanne; Nickels, Lyndsey; Hersh, Deborah; Godecke, Erin; O'Halloran, Robyn; Lamont, Sue; O'Connor, Claire; Clarke, Kim

    2015-01-01

    Objectives To develop and validate a national set of best practice statements for use in post-stroke aphasia rehabilitation. Design Literature review and statement validation using the RAND/UCLA Appropriateness Method (RAM). Participants A national Community of Practice of over 250 speech pathologists, researchers, consumers and policymakers developed a framework consisting of eight areas of care in aphasia rehabilitation. This framework provided the structure for the development of a care pathway containing aphasia rehabilitation best practice statements. Nine speech pathologists with expertise in aphasia rehabilitation participated in two rounds of RAND/UCLA appropriateness ratings of the statements. Panellists consisted of researchers, service managers, clinicians and policymakers. Main outcome measures Statements that achieved a high level of agreement and an overall median score of 7–9 on a nine-point scale were rated as ‘appropriate’. Results 74 best practice statements were extracted from the literature and rated across eight areas of care (eg, receiving the right referrals, providing intervention). At the end of Round 1, 71 of the 74 statements were rated as appropriate, no statements were rated as inappropriate, and three statements were rated as uncertain. All 74 statements were then rated again in the face-to-face second round. 16 statements were added through splitting existing items or adding new statements. Seven statements were deleted leaving 83 statements. Agreement was reached for 82 of the final 83 statements. Conclusions This national set of 82 best practice statements across eight care areas for the rehabilitation of people with aphasia is the first to be validated by an expert panel. These statements form a crucial component of the Australian Aphasia Rehabilitation Pathway (AARP) (http://www.aphasiapathway.com.au) and provide the basis for more consistent implementation of evidence-based practice in stroke rehabilitation. PMID:26137883

  5. "Nafta ja veri : Balti energia ja kommunismi pärand" : ÜBAK-i 7. Balti konverents / Karl Altau

    Index Scriptorium Estoniae

    Altau, Karl Stephen, 1959-

    2007-01-01

    eelteade Ühendatud Balti Ameerika Komitee korraldusel toimuvast konverentsist Washingtonis 9.-10. veebruarini -teemaks Baltimaade energeetiline julgeolek ja kommunismi pärand, peakõnelejaks Valdas Adamkus. Info: jbanc@jbanc.org või telefon 301-340-1954

  6. Legal issues concerning mine closure and social responsibility on the West Rand

    Directory of Open Access Journals (Sweden)

    Francois Durand

    2009-04-01

    Full Text Available Mining and, especially, gold and uranium mining have played a major role in the economy, history, and demography of South Africa. The contribution of the mines to the economy of South Africa over the past century has been overvalued, while the social injustices and negative environmental impacts that accompanied mining have been underplayed or ignored by the mining houses and government. The environmental situation has worsened significantly over the past few years due to the abandonment and pending closure of most of these mines. A reluctance is perceived on the part of the mining companies, and even government, to take responsibility for the damage caused by pollution, ecological degradation, and impact on human health by mining. Instead, the current informal policy appears to take smaller companies to court on minor environmental injustices to, perhaps, impress the broader public, while one of the biggest environmental concerns is stylishly treated. The inability of government to address the damage by mines effectively is in conflict with the National Water Act, the National Environmental Management Act, the Mineral and Petroleum Resources Act, the National Nuclear Regulator Act, and the Constitution of South Africa. The authors propose a multidisciplinary approach to address water-related environmental injustices on the West Rand and Far West Rand. We also describe the application of the National Environmental Management Act of South Africa (Act No. 107 of 1998 in the Wonderfonteinspruit and Tweelopiespruit Catchments and the current water quality situation.

  7. Excess molar volumes of binary mixtures (an ionic liquid + water): A review

    International Nuclear Information System (INIS)

    Bahadur, Indra; Letcher, Trevor M.; Singh, Sangeeta; Redhi, Gan G.; Venkatesu, Pannuru; Ramjugernath, Deresh

    2015-01-01

    Highlights: • Review of excess molar volumes for mixtures of (ionic liquids (ILs) + H 2 O). • 6 cation groups reviewed including imidazolium and pyrrolidinium groups. • 13 anions reviewed including tetraborate, triflate, and hydrogensulphate. • Effects of anion, cation, and temperature investigated. - Abstract: This review covers recent developments in the area of excess molar volumes for mixtures of {ILs (1) + H 2 O (2)} where ILs refers to ionic liquids involving cations: imidazolium, pyridinium, pyrrolidinium, piperidinium, morpholinium and ammonium groups; and anions: tetraborate, triflate, hydrogensulphate, methylsulphate, ethylsulphate, thiocyanate, dicyanamide, octanate, acetate, nitrate, chloride, bromide, and iodine. The excess molar volumes of aqueous ILs were found to cover a wide range of values for the different ILs (ranging from −1.7 cm 3 · mol −1 to 1.2 cm 3 · mol −1 ). The excess molar volumes increased with increasing temperature for all systems studied in this review. The magnitude and in some cases the sign of the excess molar volumes for all the aqueous ILs mixtures, apart from the ammonium ILs, were very dependent on temperature. This was particularly important in the dilute IL concentration region. It was found that the sign and magnitude of the excess molar volumes of aqueous ILs (for ILs with hydrophobic cations), was more dependent on the nature of the anion than on the cation

  8. An Analysis of the Objectivist Ethics in Educational Leadership through Ayn Rand's "The Virtues of Selfishness" (1964)

    Science.gov (United States)

    Jacobs, Karen Dupre; Kritsonis, William Allan

    2007-01-01

    Educational leadership is vital to sustain quality educational institutions. It is the role of the school leader to indoctrinate stakeholders with the objectivist ethics-embracing egoism and relinquishing altruistic ideals when it comes to invigorating the system with sustainable change. Ayn Rand's timeless piece of literature "The Virtue of…

  9. Development of generic quality indicators for patient-centered cancer care by using a RAND modified Delphi method

    NARCIS (Netherlands)

    Uphoff, Eleonora P. M. M.; Wennekes, Lianne; Punt, Cornelis J. A.; Grol, Richard P. T. M.; Wollersheim, Hub C. H.; Hermens, Rosella P. M. G.; Ottevanger, Petronella B.

    2012-01-01

    Despite growing attention to patient-centered care, the needs of cancer patients are not always met. Using a RAND modified Delphi method, this study aimed to systematically develop evidence-based indicators, to be used to measure the quality of patient-centered cancer care as a first step toward

  10. Development and validation of Australian aphasia rehabilitation best practice statements using the RAND/UCLA appropriateness method.

    Science.gov (United States)

    Power, Emma; Thomas, Emma; Worrall, Linda; Rose, Miranda; Togher, Leanne; Nickels, Lyndsey; Hersh, Deborah; Godecke, Erin; O'Halloran, Robyn; Lamont, Sue; O'Connor, Claire; Clarke, Kim

    2015-07-02

    To develop and validate a national set of best practice statements for use in post-stroke aphasia rehabilitation. Literature review and statement validation using the RAND/UCLA Appropriateness Method (RAM). A national Community of Practice of over 250 speech pathologists, researchers, consumers and policymakers developed a framework consisting of eight areas of care in aphasia rehabilitation. This framework provided the structure for the development of a care pathway containing aphasia rehabilitation best practice statements. Nine speech pathologists with expertise in aphasia rehabilitation participated in two rounds of RAND/UCLA appropriateness ratings of the statements. Panellists consisted of researchers, service managers, clinicians and policymakers. Statements that achieved a high level of agreement and an overall median score of 7-9 on a nine-point scale were rated as 'appropriate'. 74 best practice statements were extracted from the literature and rated across eight areas of care (eg, receiving the right referrals, providing intervention). At the end of Round 1, 71 of the 74 statements were rated as appropriate, no statements were rated as inappropriate, and three statements were rated as uncertain. All 74 statements were then rated again in the face-to-face second round. 16 statements were added through splitting existing items or adding new statements. Seven statements were deleted leaving 83 statements. Agreement was reached for 82 of the final 83 statements. This national set of 82 best practice statements across eight care areas for the rehabilitation of people with aphasia is the first to be validated by an expert panel. These statements form a crucial component of the Australian Aphasia Rehabilitation Pathway (AARP) (http://www.aphasiapathway.com.au) and provide the basis for more consistent implementation of evidence-based practice in stroke rehabilitation. Published by the BMJ Publishing Group Limited. For permission to use (where not already

  11. An interest group at work: Environmental activism and the case of acid mine drainage on Johannesburg’s West Rand

    CSIR Research Space (South Africa)

    Funke, Nicola S

    2012-02-01

    Full Text Available -product of mining. This chapter analyses environmental interest groups that campaign on the AMD issue on Johannesburg’s West Rand. To contextualise these advocacy efforts, the chapter scientifically outlines why AMD is a fundamental problem and what socio...

  12. "rand on klaasist ..." = "strondin er av glasi ..." : [luuletused] / T̤roddur Poulsen ; tlk. Arvo Alas

    Index Scriptorium Estoniae

    Poulsen, T̤roddur

    2004-01-01

    Sisu: "rand on klaasist ..." = "strondin er av glasi ..."; "vesi kannab endas ka nukrust ..." = "vatiņ ber eisini sorg ..."; "Nägin unes et olid ..." = "Droymdi at t{250} ..."; "Tulevik kuulub lihale ..." = "Visi̤nin er kjaet ..."; "Ma pole kirjutanud ..." = "Eg har ikki skriva̧ ..."; "Fäärid sinus. Fäärid minus. Fäärid sidrunis. Fäärid ..." = "Faeroyar Í t̆r. Faeroyar Í m̆r. Faeroyar Í citr̤nini. Faeroyar ... "; "Ma ei suuda kirjutada ..." = "Eg kan ikki skriva ..."

  13. Validation of Portuguese version of Quality of Erection Questionnaire (QEQ) and comparison to International Index of Erectile Function (IIEF) and RAND 36-Item Health Survey.

    Science.gov (United States)

    Reis, Ana Luiza; Reis, Leonardo Oliveira; Saade, Ricardo Destro; Santos, Carlos Alberto; Lima, Marcelo Lopes de; Fregonesi, Adriano

    2015-01-01

    To validate the Quality of Erection Questionnaire (QEQ) considering Brazilian social-cultural aspects. To determine equivalence between the Portuguese and the English QEQ versions, the Portuguese version was back-translated by two professors who are native English speakers. After language equivalence had been determined, urologists considered the QEQ Portuguese version suitable. Men with self-reported erectile dysfunction (ED) and infertile men who had a stable sexual relationship for at least 6 months were invited to answer the QEQ, the International Index of Erectile Function (IIEF) and the RAND 36-Item Health Survey (RAND-36). The questionnaires were presented together and answered without help in a private room. Internal consistency (Cronbach's α), test-retest reliability (Spearman), convergent validity (Spearman correlation) coefficients and known-groups validity (the ability of the QEQ Portuguese version to differentiate erectile dysfunction severity groups) were assessed. We recruited 197 men (167 ED patients and 30 non-ED patients), mean age of 53.3 and median of 55.5 years (23-82 years). The Portuguese version of the QEQ had high internal consistency (Cronbach α=0.93), high stability between test and retest (ICC 0.83, with IC 95%: 0.76-0.88, pPortuguese version presented good psychometric properties and high convergent validity in relation to IIEF. The low correlations between the QEQ and the RAND-36, as well as between the IIEF and the RAND-36 indicated IIEF and QEQ specificity, which may have resulted from the patients' psychological adaptations that minimized the impact of ED on Quality of Life (QoL) and reestablished the well-being feeling.

  14. Key interventions and quality indicators for quality improvement of STEMI care: a RAND Delphi survey.

    Science.gov (United States)

    Aeyels, Daan; Sinnaeve, Peter R; Claeys, Marc J; Gevaert, Sofie; Schoors, Danny; Sermeus, Walter; Panella, Massimiliano; Coeckelberghs, Ellen; Bruyneel, Luk; Vanhaecht, Kris

    2017-12-13

    Identification, selection and validation of key interventions and quality indicators for improvement of in hospital quality of care for ST-elevated myocardial infarction (STEMI) patients. A structured literature review was followed by a RAND Delphi Survey. A purposively selected multidisciplinary expert panel of cardiologists, nurse managers and quality managers selected and validated key interventions and quality indicators prior for quality improvement for STEMI. First, 34 experts (76% response rate) individually assessed the appropriateness of items to quality improvement on a nine point Likert scale. Twenty-seven key interventions, 16 quality indicators at patient level and 27 quality indicators at STEMI care programme level were selected. Eighteen additional items were suggested. Experts received personal feedback, benchmarking their score with group results (response rate, mean, median and content validity index). Consequently, 32 experts (71% response rate) openly discussed items with an item-content validity index above 75%. By consensus, the expert panel validated a final set of 25 key interventions, 13 quality indicators at patient level and 20 quality indicators at care programme level prior for improvement of in hospital care for STEMI. A structured literature review and multidisciplinary expertise was combined to validate a set of key interventions and quality indicators prior for improvement of care for STEMI. The results allow researchers and hospital staff to evaluate and support quality improvement interventions in a large cohort within the context of a health care system.

  15. A label field fusion bayesian model and its penalized maximum rand estimator for image segmentation.

    Science.gov (United States)

    Mignotte, Max

    2010-06-01

    This paper presents a novel segmentation approach based on a Markov random field (MRF) fusion model which aims at combining several segmentation results associated with simpler clustering models in order to achieve a more reliable and accurate segmentation result. The proposed fusion model is derived from the recently introduced probabilistic Rand measure for comparing one segmentation result to one or more manual segmentations of the same image. This non-parametric measure allows us to easily derive an appealing fusion model of label fields, easily expressed as a Gibbs distribution, or as a nonstationary MRF model defined on a complete graph. Concretely, this Gibbs energy model encodes the set of binary constraints, in terms of pairs of pixel labels, provided by each segmentation results to be fused. Combined with a prior distribution, this energy-based Gibbs model also allows for definition of an interesting penalized maximum probabilistic rand estimator with which the fusion of simple, quickly estimated, segmentation results appears as an interesting alternative to complex segmentation models existing in the literature. This fusion framework has been successfully applied on the Berkeley image database. The experiments reported in this paper demonstrate that the proposed method is efficient in terms of visual evaluation and quantitative performance measures and performs well compared to the best existing state-of-the-art segmentation methods recently proposed in the literature.

  16. Annual Review of Applied Linguistics, Volume 5, 1984.

    Science.gov (United States)

    Kaplan, Robert B., Ed.

    This volume of the annual review includes introductory remarks by G. Richard Tucker and these papers: "Current Issues in Bilingualism: An Update of Directions in Research" (Braj B. Kachru); "Psycholinguistics: Application. The Writing System as a Native Language for the Deaf" (Danny D. Steinberg); "Sociolinguistics: Theory" (Monica Heller);…

  17. Learning from Experience, Volume 2: Lessons from the U.S. Navy’s Ohio, Seawolf, and Virginia Submarine Programs

    Science.gov (United States)

    2011-01-01

    commercial use. For information on reprint and linking permissions, please see RAND Permissions. Skip all front matter: Jump to Page 16 The RAND...law. For information on reprint and linking permissions, please visit the RAND permissions page (http://www.rand.org/publications/ permissions.html... pedo payload at 50 to allow the submarine to remain in a forward combat area without resupply for an extended period of time. These aggressive

  18. Optimization of physical factors affecting the production of thermo-stable organic solvent-tolerant protease from a newly isolated halo tolerant Bacillus subtilis strain Rand

    Directory of Open Access Journals (Sweden)

    Salleh Abu

    2009-04-01

    Full Text Available Abstract Background Many researchers have reported on the optimization of protease production; nevertheless, only a few have reported on the optimization of the production of organic solvent-tolerant proteases. Ironically, none has reported on thermostable organic solvent-tolerant protease to date. The aim of this study was to isolate the thermostable organic solvent-tolerant protease and identify the culture conditions which support its production. The bacteria of genus Bacillus are active producers of extra-cellular proteases, and the thermostability of enzyme production by Bacillus species has been well-studied by a number of researchers. In the present study, the Bacillus subtilis strain Rand was isolated from the contaminated soil found in Port Dickson, Malaysia. Results A thermostable organic solvent-tolerant protease producer had been identified as Bacillus subtilis strain Rand, based on the 16S rRNA analysis conducted, as well as the morphological characteristics and biochemical properties. The production of the thermostable organic solvent-tolerant protease was optimized by varying various physical culture conditions. Inoculation with 5.0% (v/v of (AB600 = 0.5 inoculum size, in a culture medium (pH 7.0 and incubated for 24 h at 37°C with 200 rpm shaking, was the best culture condition which resulted in the maximum growth and production of protease (444.7 U/ml; 4042.4 U/mg. The Rand protease was not only stable in the presence of organic solvents, but it also exhibited a higher activity than in the absence of organic solvent, except for pyridine which inhibited the protease activity. The enzyme retained 100, 99 and 80% of its initial activity, after the heat treatment for 30 min at 50, 55, and 60°C, respectively. Conclusion Strain Rand has been found to be able to secrete extra-cellular thermostable organic solvent-tolerant protease into the culture medium. The protease exhibited a remarkable stability towards temperature and organic

  19. Ensuring the Quality and Productivity of Education and Professional Development Activities: A Review of Approaches and Lessons for DoD

    National Research Council Canada - National Science Library

    Gates, Susan

    2001-01-01

    .... In support of this aim, the Chancellor asked RAND to review existing approaches for assessing academic quality and productivity and to suggest approaches that might be useful for the assessment...

  20. Sexual Assault and Sexual Harassment in the U.S. Military: Evaluating Estimates from the 2014 RAND Military Workplace Study

    Science.gov (United States)

    2016-01-01

    harassment, and gender discrimination in the military. The RAND Military Workplace Study (RMWS) included one of the largest surveys of its kind: Almost...approach to counting service members who experienced sexual assault, sexual harassment, and gender discrimination , providing DoD with unprecedented...harassment, or gender discrimination . Specifically, both the phone and web follow-up surveys revealed possible nonresponse bias in the RMWS estimates, but

  1. Proceedings of the 1995 U.S. DOE hydrogen program review, Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    This document containes reports from the proceedings of the 1995 U.S. DOE hydrogen program review. Reports are organized under the topics of systems analysis, utilization, storage, and production. This volume, Volume I, contains the reports concerned with systems analysis and utilization. Individual reports were processed separately for the DOE data bases.

  2. Human-system interface design review guideline -- Review software and user's guide: Final report. Revision 1, Volume 3

    International Nuclear Information System (INIS)

    1996-06-01

    NUREG-0700, Revision 1, provides human factors engineering (HFE) guidance to the US Nuclear Regulatory Commission staff for its: (1) review of the human system interface (HSI) design submittals prepared by licensees or applications for a license or design certification of commercial nuclear power plants, and (2) performance of HSI reviews that could be undertaken as part of an inspection or other type of regulatory review involving HSI design or incidents involving human performance. The guidance consists of a review process and HFE guidelines. The document describes those aspects of the HSI design review process that are important to the identification and resolution of human engineering discrepancies that could adversely affect plant safety. Guidance is provided that could be used by the staff to review an applicant's HSI design review process or to guide the development of an HSI design review plan, e.g., as part of an inspection activity. The document also provides detailed HFE guidelines for the assessment of HSI design implementations. NUREG-0700, Revision 1, consists of three stand-alone volumes. Volume 3 contains an interactive software application of the NUREG-0700, Revision 1 guidance and a user's guide for this software. The software supports reviewers during review preparation, evaluation design using the human factors engineering guidelines, and in report preparation. The user's guide provides system requirements and installation instructions, detailed explanations of the software's functions and features, and a tutorial on using the software

  3. An analysis of appropriate delivery of postoperative radiation therapy for endometrial cancer using the RAND/UCLA Appropriateness Method: Executive summary

    Directory of Open Access Journals (Sweden)

    Ellen Jones, MD, PhD

    2016-01-01

    Conclusions: This analysis based on the RAND/UCLA Method shows significant agreement with the 2014 endometrial Guideline. Areas of divergence, often in scenarios with low-level evidence, included use of external beam RT plus vaginal brachytherapy in stages II and III and external beam RT alone in early-stage patients. Furthermore, the analysis explores other important questions regarding management of this disease site.

  4. Report of the US Nuclear Regulatory Commission Piping Review Committee. Volume 5. Summary - Piping Review Committee conclusions and recommendations

    International Nuclear Information System (INIS)

    1985-04-01

    This document summarizes a comprehensive review of NRC requirements for Nuclear Piping by the US NRC Piping Review Committee. Four topical areas, addressed in greater detail in Volumes 1 through 4 of this report, are included: (1) Stress Corrosion Cracking in Piping of Boiling Water Reactor Plants; (2) Evaluation of Seismic Design; (3) Evaluation of Potential for Pipe Breaks; and (4) Evaluation of Other Dynamic Loads and Load Combinations. This volume summarizes the major issues, reviews the interfaces, and presents the Committee's conclusions and recommendations for updating NRC requirements on these issues. This report also suggests research or other work that may be required to respond to issues not amenable to resolution at this time

  5. Recovery of Navy distillate fuel from reclaimed product. Volume II. Literature review

    Energy Technology Data Exchange (ETDEWEB)

    Brinkman, D.W.; Whisman, M.L.

    1984-11-01

    In an effort to assist the Navy to better utilize its waste hydrocarbons, NIPER, with support from the US Department of Energy, is conducting research designed to ultimately develop a practical technique for converting Reclaimed Product (RP) into specification Naval Distillate Fuel (F-76). This first phase of the project was focused on reviewing the literature and available information from equipment manufacturers. The literature survey has been carefully culled for methodology applicable to the conversion of RP into diesel fuel suitable for Navy use. Based upon the results of this study, a second phase has been developed and outlined in which experiments will be performed to determine the most practical recycling technologies. It is realized that the final selection of one particular technology may be site-specific due to vast differences in RP volume and available facilities. A final phase, if funded, would involve full-scale testing of one of the recommended techniques at a refueling depot. The Phase I investigations are published in two volumes. Volume 1, Technical Discussion, includes the narrative and Appendices I and II. Appendix III, a detailed Literature Review, includes both a narrative portion and an annotated bibliography containing about 800 references and abstracts. This appendix, because of its volume, has been published separately as Volume 2.

  6. Solcellsparkeringen : En jämförande fallstudie för elbilar och bensinbilar

    OpenAIRE

    Myrén Andersson, Isac; Yttermyr-Sütt, Frans

    2017-01-01

    Av Sveriges totala växthusgasutsläpp är det i nuläget transportsektorn som står för den största andelen och står för mer än 30 % av alla utsläpp. Med ett ökande fordonsbestånd och ett fortsatt behov av transporter blir lösningar som minskar utsläppen från denna sektor avgörande för Sveriges hållbara utveckling. Eftersom 93 % av Sveriges drygt 4,7 miljoner personbilar drivs av fossila bränslen skulle investeringar i alternativa färdmedel såsom elbilar kunna leda Sverige i rätt riktning. Förfat...

  7. Report of the Review Committee on the BNL colliding beam accelerator

    International Nuclear Information System (INIS)

    1983-01-01

    The Colliding Beam Accelerator (CBA) proposal by BNL for a pp collider of 400 GeV /times/ 400 GeV with a maximum luminosity /Brit pounds/ = 2 /times/ 10 33 was reviewed by a DOE team, including consultants, on April 11--15, 1983. No major flaws were found that would prevent, in principle, the proposed collider from reaching its design goals. BNL has made sufficient progress in their superconducting magnet RandD program that, although there is not yet a magnet of the CBA baseline design, the Committee believes the design can be achieved. However, to ensure prompt completion of the project, substantial RandD needs to be carried out in short order, particularly on the timely and cost-effective production of magnets, reliability of quench protection, and determination of cryogenic heat loads

  8. Online doctor reviews: do they track surgeon volume, a proxy for quality of care?

    Science.gov (United States)

    Segal, Jeffrey; Sacopulos, Michael; Sheets, Virgil; Thurston, Irish; Brooks, Kendra; Puccia, Ryan

    2012-04-10

    Increasingly, consumers are accessing the Internet seeking health information. Consumers are also using online doctor review websites to help select their physician. Such websites tally numerical ratings and comments from past patients. To our knowledge, no study has previously analyzed whether doctors with positive online reputations on doctor review websites actually deliver higher quality of care typically associated with better clinical outcomes and better safety records. For a number of procedures, surgeons who perform more procedures have better clinical outcomes and safety records than those who perform fewer procedures. Our objective was to determine if surgeon volume, as a proxy for clinical outcomes and patient safety, correlates with online reputation. We investigated the numerical ratings and comments on 9 online review websites for high- and low-volume surgeons for three procedures: lumbar surgery, total knee replacement, and bariatric surgery. High-volume surgeons were randomly selected from the group within the highest quartile of claims submitted for reimbursement using the procedures' relevant current procedural terminology (CPT) codes. Low-volume surgeons were randomly selected from the lowest quartile of submitted claims for the procedures' relevant CPT codes. Claims were collated within the Normative Health Information Database, covering multiple payers for more than 25 million insured patients. Numerical ratings were found for the majority of physicians in our sample (547/600, 91.2%) and comments were found for 385/600 (64.2%) of the physicians. We found that high-volume (HV) surgeons could be differentiated from low-volume (LV) surgeons independently by analyzing: (1) the total number of numerical ratings per website (HV: mean = 5.85; LV: mean = 4.87, Pcustomer service (HV: mean = 0.24; LV: mean = 0.22, P=.52); and (3) proportion of scathing criticism/total comments about customer service (HV: mean = 0.19; LV: mean = 0.21, P=.48). Online

  9. Index to Nuclear Safety: a technical progress review by chrology, permuted title, and author, Volume 11(1) through Volume 20(6)

    Energy Technology Data Exchange (ETDEWEB)

    Cottrell, W B; Passiakos, M

    1980-06-01

    This index to Nuclear Safety, a bimonthly technical progress review, covers articles published in Nuclear Safety, Volume II, No. 1 (January-February 1970), through Volume 20, No. 6 (November-December 1979). It is divided into three sections: a chronological list of articles (including abstracts) followed by a permuted-title (KWIC) index and an author index. Nuclear Safety, a bimonthly technical progress review prepared by the Nuclear Safety Information Center (NSIC), covers all safety aspects of nuclear power reactors and associated facilities. Over 600 technical articles published in Nuclear Safety in the last ten years are listed in this index.

  10. Trading volume in financial markets: An introductory review

    International Nuclear Information System (INIS)

    Duarte Queirós, Sílvio M.

    2016-01-01

    In this article, I introduce a short review on the statistical and dynamical properties of the high-frequency trading volume and its relation to other financial quantities such as the price fluctuations and trading value. In addition, I compare these results — which were obtained within the framework of applications of Physics to quantitative financial analysis —with the mainstream financial hypotheses of mixture of distributions (MDH) and sequential arrival of information (SIAH).

  11. Development of quality indicators for low-risk labor care provided by midwives using a RAND-modified Delphi method.

    Science.gov (United States)

    Ueda, Kayo; Ohtera, Shosuke; Kaso, Misato; Nakayama, Takeo

    2017-09-22

    In childbirth, most deliveries are low-risk, defined as spontaneous labor at full term without special high-risk facts or complications, especially in high-resource countries where maternal and perinatal mortality rates are very low. Indeed, the majority of mothers and infants have no serious conditions during labor. However, the quality of care provided is not assured, and performance may vary by birthing facility and provider. The overuse of technology in childbirth in some parts of the world is almost certainly based on assumptions like, "something can go wrong at any minute." There is a need to assess the quality of care provided for mothers and infants in low-risk labor. We aimed to develop specific quality indicators for low-risk labor care provided primarily by midwives in Japan. We used a RAND-modified Delphi method, which integrates evidence review with expert consensus development. The procedure comprises five steps: (1) literature review, including clinical practice guidelines, to extract and develop quality indicator candidates; (2) formation of a multidisciplinary panel; (3) independent panel ratings (Round 1); (4) panel meeting and independent panel ratings (Round 2); and (5) independent panel ratings (Round 3). The three independent panel ratings (Rounds 1-3) were held between July and December 2012. The assembled multidisciplinary panel comprised eight clinicians (two pediatricians, three obstetricians, and three midwives) and three mothers who were nonclinicians. Evidentiary review extracted 166 key recommendations from 32 clinical practice guidelines, and 31 existing quality indicators were added. After excluding duplicate recommendations and quality indicators, the panel discussed 25 candidate indicators. Of these, 18 were adopted, one was modified, six were not adopted, and four were added during the meeting, respectively. We established 23 quality indicators for low-risk labor care provided by midwives in labor units in Japan.

  12. Strategic process strengthens and orientates the regional RandD capacity

    Energy Technology Data Exchange (ETDEWEB)

    Knuuttila, Kirsi [JAMK Univ. of Applied Sciences, Jyvaeskylae (Finland)], e-mail: kirsi.knuuttila@jamk.fi; Krissakova, Ingrid [National Forest Centre-Forest Research Inst., Zvolen (Slovakia); Barbena, Goizeder [Centro Nacional de Energias Renovables/ Departamento de Biomasa, CENER, Pamplona (Spain); Hryniewicz, Marek [Inst. of Technology and Life Sciences, ITP, Raszyn (Poland); Ketikidis, Chrysovalantis [Centre for Research and Technology Hellas, CERTH/ Inst. for Solid Fuels Technology and Applications, Thessaloniki (Greece); Wihersaari, Margareta [Jyvaeskylae Univ., Jyvaeskylae (Finland)

    2012-11-01

    The use of biomasses and competition for biomass resources are rapidly increasing in Europe due to the positive environmental advantages that this energy source entails, including climate change prevention. Central Finland, Navarra (Spain), Western Macedonia (Greece), Slovakia and Wielkopolska (Poland) have taken the joint initiative to strengthen the regional expertise, cooperation capacities and innovation environment in the field of sustainable use of biomass resources. The initiative to develop the regional research driven clusters is supported by BIOCLUS project (www.bioclus.eu) co-financed by FP7 Regions of Knowledge Programme. The biomass research orientated clusters have built up Regional Strategic RandD Agendas (SRA) and Joint Action Plans (JAP) based on the SRAs. The starting point for SRA is the comprehensive understanding of regional biomass resources. SRA and JAP process orientates and strengthens research activities and capacity building in the selected research fields related to sustainable use of biomass. The agenda supports expertise development and cooperation in the regional research-driven cluster. It identifies the focus of research activities in the future and supports the authorities in directing the use of human and financial resources.

  13. Human factors evaluation of teletherapy: Literature review. Volume 5

    Energy Technology Data Exchange (ETDEWEB)

    Henriksen, K.; Kaye, R.D.; Jones, R. [Hughes Training, Inc., Falls Church, VA (United States); Morisseau, D.S.; Serig, D.L. [Nuclear Regulatory Commission, Washington, DC (United States). Div. of Systems Technology

    1995-07-01

    A series of human factors evaluations were undertaken to better understand the contributing factors to human error in the teletherapy environment. Teletherapy is a multidisciplinary methodology for treating cancerous tissue through selective exposure to an external beam of ionizing radiation. A team of human factors specialists, assisted by a panel of radiation oncologists, medical physicists, and radiation therapists, conducted site visits to radiation oncology departments at community hospitals, university centers, and free-standing clinics. A function and task analysis was performed initially to guide subsequent evaluations in the areas of workplace environment, system-user interfaces, procedures, training, and organizational practices. To further acquire an in-depth and up-to-date understanding of the practice of teletherapy in support of these evaluations, a systematic literature review was conducted. Factors that have a potential impact on the accuracy of treatment delivery were of primary concern. The present volume is the literature review. The volume starts with an overview of the multiphased nature of teletherapy, and then examines the requirement for precision, the increasing role of quality assurance, current conceptualizations of human error, and the role of system factors such as the workplace environment, user-system interfaces, procedures, training, and organizational practices.

  14. Human factors evaluation of teletherapy: Literature review. Volume 5

    International Nuclear Information System (INIS)

    Henriksen, K.; Kaye, R.D.; Jones, R.; Morisseau, D.S.; Serig, D.L.

    1995-07-01

    A series of human factors evaluations were undertaken to better understand the contributing factors to human error in the teletherapy environment. Teletherapy is a multidisciplinary methodology for treating cancerous tissue through selective exposure to an external beam of ionizing radiation. A team of human factors specialists, assisted by a panel of radiation oncologists, medical physicists, and radiation therapists, conducted site visits to radiation oncology departments at community hospitals, university centers, and free-standing clinics. A function and task analysis was performed initially to guide subsequent evaluations in the areas of workplace environment, system-user interfaces, procedures, training, and organizational practices. To further acquire an in-depth and up-to-date understanding of the practice of teletherapy in support of these evaluations, a systematic literature review was conducted. Factors that have a potential impact on the accuracy of treatment delivery were of primary concern. The present volume is the literature review. The volume starts with an overview of the multiphased nature of teletherapy, and then examines the requirement for precision, the increasing role of quality assurance, current conceptualizations of human error, and the role of system factors such as the workplace environment, user-system interfaces, procedures, training, and organizational practices

  15. LLE review. Volume 65. Quarterly report, October--December 1995

    Energy Technology Data Exchange (ETDEWEB)

    Boehly, T.R. [ed.

    1996-06-01

    This volume of the LLE Review, covering the period October-December 1995, contains a description of the generation and characterization of continuous, deep-surface-relief phase plates that are more efficient and versatile than previous designs. The LLE program plan has scheduled a number of enhancements to OMEGA`s performance and uniformity, the first of which is the implementation of these new distributed phase plates. Other articles in this volume include the discussion of an x-ray diagnostic method to measure shell-fuel mixing, the theoretical analysis of ablation-front stability, a description of a major subsystem in the OMEGA control system software, a study of the population inversions in intensely pumped Nd:YLF, and a description of a new ultrafast laser system and its uses.

  16. The New 2nd-Generation SRF RandD Facility at Jefferson Lab: TEDF

    International Nuclear Information System (INIS)

    Reece, Charles E.; Reilly, Anthony V.

    2012-01-01

    The US Department of Energy has funded a near-complete renovation of the SRF-based accelerator research and development facilities at Jefferson Lab. The project to accomplish this, the Technical and Engineering Development Facility (TEDF) Project has completed the first of two phases. An entirely new 3,100 m 2 purpose-built SRF technical work facility has been constructed and was occupied in summer of 2012. All SRF work processes with the exception of cryogenic testing have been relocated into the new building. All cavity fabrication, processing, thermal treatment, chemistry, cleaning, and assembly work is collected conveniently into a new LEED-certified building. An innovatively designed 800 m2 cleanroom/chemroom suite provides long-term flexibility for support of multiple RandD and construction projects as well as continued process evolution. The characteristics of this first 2nd-generation SRF facility are described

  17. Sexual Assault and Sexual Harassment in the U.S. Military: Top-Line Estimates for Active-Duty Service Members from the 2014 RAND Military Workplace Study

    Science.gov (United States)

    2014-01-01

    enhance the validity of their answers. The development of this new approach to measuring sexual assault and sex-based MEO violations was completed...include the buttocks, inner thigh, breast, groin, anus, vagina, penis and testicles. Top-Line Results from the RAND Military Workplace Study 41 12

  18. Prerequisites concerning SSI:s review of applications for an encapsulation facility and a repository for spent nuclear fuel

    International Nuclear Information System (INIS)

    Oehlen, Elisabeth

    2006-09-01

    The report outlines some fundamental prerequisites concerning SSI:s review of SKB coming applications for an encapsulation facility (according to the act on nuclear activities) and for the complete final disposal system (according to the act on nuclear activities and the environmental code). The report summarize how the SSI look at the decision making process considering radiation protection requirements according to SSI:s regulations and general advices and earlier standpoints regarding SKB:s RandD-programme. The report also describe the present reviewing capacity of SSI and constitute therefore the basis for the planning of SSI:s review organisation in the prospect of coming applications on nuclear waste facilities (encapsulation facility and a deep disposal repository). It should be noted that the report reflects the present situation. Due to a number of factors as for example changes in SKB:s coming RandD-programme, future governmental decisions, adjustments of SSI:s financial resources or new facts in the case, will of course have an effect on how SSI finally will organise the review work. SSI:s home page will continuously be updated with the latest information in this respect

  19. Radiologic measurement of extraocular muscle volumes in patients with Graves' orbitopathy: a review and guideline

    NARCIS (Netherlands)

    Bijlsma, Ward R.; Mourits, Maarten Ph

    2006-01-01

    OBJECTIVE: To evaluate and compare techniques for extraocular muscle (EOM) volume measurement and to provide guidelines for future measurements. DESIGN: Systematic review. RESULTS: Existing techniques used to measure extraocular muscle volumes on radiologic scans can be divided into manual

  20. State of the art review of radioactive waste volume reduction techniques for commercial nuclear power plants

    International Nuclear Information System (INIS)

    1980-04-01

    A review is made of the state of the art of volume reduction techniques for low level liquid and solid radioactive wastes produced as a result of: (1) operation of commercial nuclear power plants, (2) storage of spent fuel in away-from-reactor facilities, and (3) decontamination/decommissioning of commercial nuclear power plants. The types of wastes and their chemical, physical, and radiological characteristics are identified. Methods used by industry for processing radioactive wastes are reviewed and compared to the new techniques for processing and reducing the volume of radioactive wastes. A detailed system description and report on operating experiences follow for each of the new volume reduction techniques. In addition, descriptions of volume reduction methods presently under development are provided. The Appendix records data collected during site surveys of vendor facilities and operating power plants. A Bibliography is provided for each of the various volume reduction techniques discussed in the report

  1. Review of the Research Literature on Defining and Demonstrating Quality Teaching and Impact in Higher Education

    Science.gov (United States)

    Strang, Lucy; Bélanger, Julie; Manville, Catriona; Meads, Catherine

    2016-01-01

    In March 2016, the Higher Education Academy (HEA) commissioned RAND Europe to conduct a literature review of research published since 2012, with the aim of identifying and summarising the key trends and issues in the literature on how "quality teaching" and its impact are currently being defined and demonstrated at higher education…

  2. GPU v. B and W lawsuit review and its effect on TMI-1 (Docket 50-289). Volume 2. Appendices

    International Nuclear Information System (INIS)

    1983-09-01

    Volume II of the GPU v. B and W lawsuit review contains four appendices supporting the review of the GPU v. B and W lawsuit discussed in Volume I of this report. As outlined in the Background section of Volume I under (3) Review Method Utilized by the Staff, the GPU v. B and W lawsuit review was partitioned into 10 categories. The 154 certification items and the 19 long-term actions (hearing items or restart issues) resulting from Commission Orders and the hearing process were each placed in one or more of the 10 categories. These appendices contain the hearing items by category; lawsuit record by category; category location matrix for lawsuit record; and uncategorized lawsuit record

  3. [Target volume margins for lung cancer: internal target volume/clinical target volume].

    Science.gov (United States)

    Jouin, A; Pourel, N

    2013-10-01

    The aim of this study was to carry out a review of margins that should be used for the delineation of target volumes in lung cancer, with a focus on margins from gross tumour volume (GTV) to clinical target volume (CTV) and internal target volume (ITV) delineation. Our review was based on a PubMed literature search with, as a cornerstone, the 2010 European Organisation for Research and Treatment of Cancer (EORTC) recommandations by De Ruysscher et al. The keywords used for the search were: radiotherapy, lung cancer, clinical target volume, internal target volume. The relevant information was categorized under the following headings: gross tumour volume definition (GTV), CTV-GTV margin (first tumoural CTV then nodal CTV definition), in field versus elective nodal irradiation, metabolic imaging role through the input of the PET scanner for tumour target volume and limitations of PET-CT imaging for nodal target volume definition, postoperative radiotherapy target volume definition, delineation of target volumes after induction chemotherapy; then the internal target volume is specified as well as tumoural mobility for lung cancer and respiratory gating techniques. Finally, a chapter is dedicated to planning target volume definition and another to small cell lung cancer. For each heading, the most relevant and recent clinical trials and publications are mentioned. Copyright © 2013. Published by Elsevier SAS.

  4. Using systematic review in occupational safety and health.

    Science.gov (United States)

    Howard, John; Piacentino, John; MacMahon, Kathleen; Schulte, Paul

    2017-11-01

    Evaluation of scientific evidence is critical in developing recommendations to reduce risk. Healthcare was the first scientific field to employ a systematic review approach for synthesizing research findings to support evidence-based decision-making and it is still the largest producer and consumer of systematic reviews. Systematic reviews in the field of occupational safety and health are being conducted, but more widespread use and adoption would strengthen assessments. In 2016, NIOSH asked RAND to develop a framework for applying the traditional systematic review elements to the field of occupational safety and health. This paper describes how essential systematic review elements can be adapted for use in occupational systematic reviews to enhance their scientific quality, objectivity, transparency, reliability, utility, and acceptability. Published 2017. This article is a U.S. Government work and is in the public domain in the USA.

  5. Complex-wide review of DOE's Low-Level Waste Management ES ampersand H vulnerabilities. Volume II. Final report

    International Nuclear Information System (INIS)

    1996-05-01

    Volume I of this report presents a summary of DOE's complex-wide review of its low-level waste management system, including the assessment scope and methodology, site-specific and complex-wide vulnerabilities, and DOE's conclusions and recommendations. Volume II presents a more detailed discussion of the assessment methodology and evaluation instruments developed by the Assessment Working Group for identifying site-specific vulnerabilities, categorizing and classifying vulnerabilities, and identifying and analyzing complex-wide vulnerabilities. Attachments A and B of this volume contain, respectively, the Site Evaluation Survey and the Vulnerability Assessment Form used in those processes. Volume III contains the site-specific assessment reports for the 36 sites (38 facilities) assessed in the complex-wide review from which the complex-wide vulnerabilities were drawn

  6. Proceedings of the natural gas RD&D contractors review meeting, Volume II

    Energy Technology Data Exchange (ETDEWEB)

    Malone, R.D. [ed.

    1995-04-01

    This is volume II of papers which were presented at the natural gas RD&D contractors review meeting. Topics include: natural gas upgrading, storage, well drilling, completion, and stimulation. Individual papers were processed separately for the United States Department of Energy databases.

  7. LLE Review Quarterly Report (October-December 2000). Volume 85

    Energy Technology Data Exchange (ETDEWEB)

    Sources, John M. [Univ. of Rochester, NY (United States). Lab. for Laser Energetics

    2000-12-01

    This volume of the LLE Review, covering October-December 2000, begins with an article by R. Betti, M. Umansky, V. Lobatchev, V. N. Goncharov, and R. L. McCrory, who report on the development of a model for the deceleration phase of an imploding inertial fusion capsule (p. 1). The model shows that the ablative flow off the inner shell surface plays a critical role in reducing the growth rate and suppressing short-wavelength modes in the deceleration-phase Rayleigh-Taylor instability. Other articles in this volume are: The Effect of Shock Heating on the Stability of Laser-Driven Targets; Spherical Cavity Expansion in Material with Densification; Design and Performance of a Selectable-Rate Streak-Camera Deflection Ramp Generator; Unique High-Bandwidth, UV Fiber Deliver System for OMEGA Diagnostics Applications; Fabrication and Properties of an Ultrafast NbN Hot-Electron Single-Photon detector; and, Preliminary Design of NIF 2-D SSD.

  8. LLE Review Quarterly Report (April-June 2001). Volume 87

    Energy Technology Data Exchange (ETDEWEB)

    Hinterman, Thomas H. [Univ. of Rochester, NY (United States). Lab. for Laser Energetics

    2001-06-01

    This volume of the LLE Review, covering April–June 2001, features ''A Self-Calibrating, Multichannel Streak Camera for Inertial Confinement Fusion Applications'' by Dr. W. R. Donaldson, R. Boni, R. L. Keck, and P. A. Jaanimagi. This article (p. 109) describes the 60-beam streak camera system used on OMEGA and focuses on the hardware and software calibration techniques that maximize its utility. The system can diagnose each of the beams on every target shot and can measure beam energies with 8% accuracy and timing at 7 ps rms. Beam-to-beam power variations of less than 5% can be detected. Other articles in this volume are: Evolution of Shell Nonuniformities Near Peak Compression of a Spherical Implosion; Multibeam Stimulated Brillouin Scattering from Hot Solid-Target Plasmas; Hot-Electron Effect in Superconductors and Is Applications for Radiation Sensors; and, Scaling Law for Marginal Ignition.

  9. LLE Review: Volume 63. Quarterly report, April--June 1995

    International Nuclear Information System (INIS)

    Craxton, R.S.

    1995-01-01

    This volume of the LLE Review, covering the period of April--June 1995, includes a description of the initial performance results of the upgraded OMEGA laser system. A series of acceptance tests were completed, demonstrating that all 60 beams can irradiate targets with more energy and better beam balance than was required by the Department of Energy's acceptance criteria. Other articles in this volume include a description of a novel energy measurement system used to diagnose all 60 OMEGA beams; a theoretical calculation of the cutoff wave number of the ablative Rayleigh-Taylor instability, applicable to both direct and indirect drive; a description of a new algorithm used for designing distributed phase plates that will produce super-Gaussian focal-plane irradiance profiles: a study of the photoresponse of high-T c YBCO thin films; and a description of magnetorheological finishing, a new process for optics polishing

  10. LLE Review quarterly report, October--December 1992. Volume 53

    Energy Technology Data Exchange (ETDEWEB)

    Meyerhofer, D.D. [ed.

    1992-12-31

    This volume of the LLE Review covers the three-month period October--December 1992. On 18 December, the OMEGA Laser Facility fired its last shot. It will be decommissioned during the next quarter to make room for the OMEGA Upgrade Laser Facility. This volume deals with two areas of interest for the OMEGA Upgrade, the development of advanced x-ray and neutron diagnostics and the development of long-pulse (>1-ns) laser sources. The first three articles discuss the development of time-dependent diagnostics. The development of an x-ray framing camera is described and measurements of the high-voltage pulse propagation in the camera are presented. Time-resolved and time-integrated neutron diagnostics for the OMEGA Upgrade are then discussed. Two schemes for the generation of >1-ns laser pulses are presented. Finally, the activities of the National Laser Users Facility and the GDL and OMEGA laser facilities are summarized.

  11. LLE Review. Quarterly report, January--March 1992: Volume 50

    Energy Technology Data Exchange (ETDEWEB)

    Keck, R.L. [ed.

    1992-09-01

    This volume of the LLE Review, covering the period January--March 1992, contains articles on the use of diffraction gratings in laser applications, and the fabrication of gratings for use in these applications. there are two articles on the use of lasers to explore fundamental physics issues and an article on the use of a solid-state diode array for x-ray imaging. Finally, the activities of the National Laser Users Facility and the GDL and OMEGA laser systems are summarized.

  12. EUV mask defect inspection and defect review strategies for EUV pilot line and high volume manufacturing

    Science.gov (United States)

    Chan, Y. David; Rastegar, Abbas; Yun, Henry; Putna, E. Steve; Wurm, Stefan

    2010-04-01

    Reducing mask blank and patterned mask defects is the number one challenge for extreme ultraviolet lithography. If the industry succeeds in reducing mask blank defects at the required rate of 10X every year for the next 2-3 years to meet high volume manufacturing defect requirements, new inspection and review tool capabilities will soon be needed to support this goal. This paper outlines the defect inspection and review tool technical requirements and suggests development plans to achieve pilot line readiness in 2011/12 and high volume manufacturing readiness in 2013. The technical specifications, tooling scenarios, and development plans were produced by a SEMATECH-led technical working group with broad industry participation from material suppliers, tool suppliers, mask houses, integrated device manufacturers, and consortia. The paper summarizes this technical working group's assessment of existing blank and mask inspection/review infrastructure capabilities to support pilot line introduction and outlines infrastructure development requirements and tooling strategies to support high volume manufacturing.

  13. Human-system interface design review guideline -- Process and guidelines: Final report. Revision 1, Volume 1

    International Nuclear Information System (INIS)

    1996-06-01

    NUREG-0700, Revision 1, provides human factors engineering (HFE) guidance to the US Nuclear Regulatory Commission staff for its: (1) review of the human system interface (HSI) design submittals prepared by licensees or applications for a license or design certification of commercial nuclear power plants, and (2) performance of HSI reviews that could be undertaken as part of an inspection or other type of regulatory review involving HSI design or incidents involving human performance. The guidance consists of a review process and HFE guidelines. The document describes those aspects of the HSI design review process that are important to the identification and resolution of human engineering discrepancies that could adversely affect plant safety. Guidance is provided that could be used by the staff to review an applicant's HSI design review process or to guide the development of an HSI design review plan, e.g., as part of an inspection activity. The document also provides detailed HFE guidelines for the assessment of HSI design implementations. NUREG-0700, Revision 1, consists of three stand-alone volumes. Volume 1 consists of two major parts. Part 1 describes those aspects of the review process of the HSI design that are important to identifying and resolving human engineering discrepancies. Part 2 contains detailed guidelines for a human factors engineering review which identify criteria for assessing the implementation of an applicant's or licensee's HSI design

  14. Outcomes of Peripheral Endovascular Interventions Based on Hospital Volume: A Mini Review of Published Literature

    Directory of Open Access Journals (Sweden)

    Samir V Patel

    2016-01-01

    Full Text Available Previous literature showed hospital procedural volume is an independent predictor for outcomes of various cardiac procedures. However, very few studies shown similar results for peripheral endovascular interventions especially peripheral atherectomy. Here we are reviewing previously published articles to provide volume-outcome relationship for peripheral atherectomy and angioplasty with or without endovascular stenting. We found higher hospital volume significantly and independently lowers in-hospital mortality, amputation rates, peri-procedural complications, length and cost of hospitalization for peripheral endovascular interventions.

  15. Index to Nuclear Safety: a technical progress review by chronology, permuted title, and author, Volume 18 (1) through Volume 22 (6)

    International Nuclear Information System (INIS)

    Cottrell, W.B.; Passiakos, M.

    1982-06-01

    This index to Nuclear Safety covers articles published in Nuclear Safety, Volume 18, Number 1 (January-February 1977) through Volume 22, Number 6 (November-December 1981). The index is divided into three section: a chronological list of articles (including abstracts), a permuted-title (KWIC) index, and an author index. Nuclear Safety, a bimonthly technical progress review prepared by the Nuclear Safety Information Center, covers all safety aspects of nuclear power reactors and associated facilities. Over 300 technical articles published in Nuclear Safety in the last 5 years are listed in this index

  16. Index to Nuclear Safety: a technical progress review by chronology, permuted title, and author, Volume 18 (1) through Volume 22 (6)

    Energy Technology Data Exchange (ETDEWEB)

    Cottrell, W.B.; Passiakos, M.

    1982-06-01

    This index to Nuclear Safety covers articles published in Nuclear Safety, Volume 18, Number 1 (January-February 1977) through Volume 22, Number 6 (November-December 1981). The index is divided into three section: a chronological list of articles (including abstracts), a permuted-title (KWIC) index, and an author index. Nuclear Safety, a bimonthly technical progress review prepared by the Nuclear Safety Information Center, covers all safety aspects of nuclear power reactors and associated facilities. Over 300 technical articles published in Nuclear Safety in the last 5 years are listed in this index.

  17. The role of surgeon volume on patient outcome in total knee arthroplasty: a systematic review of the literature

    Directory of Open Access Journals (Sweden)

    Lau Rick L

    2012-12-01

    Full Text Available Abstract Background A number of factors have been identified as influencing total knee arthroplasty outcomes, including patient factors such as gender and medical comorbidity, technical factors such as alignment of the prosthesis, and provider factors such as hospital and surgeon procedure volumes. Recently, strategies aimed at optimizing provider factors have been proposed, including regionalization of total joint arthroplasty to higher volume centers, and adoption of volume standards. To contribute to the discussions concerning the optimization of provider factors and proposals to regionalize total knee arthroplasty practices, we undertook a systematic review to investigate the association between surgeon volume and primary total knee arthroplasty outcomes. Methods We performed a systematic review examining the association between surgeon volume and primary knee arthroplasty outcomes. To be included in the review, the study population had to include patients undergoing primary total knee arthroplasty. Studies had to report on the association between surgeon volume and primary total knee arthroplasty outcomes, including perioperative mortality and morbidity, patient-reported outcomes, or total knee arthroplasty implant survivorship. There were no restrictions placed on study design or language. Results Studies were variable in defining surgeon volume (‘low’: 5 to >70 total knee arthroplasty per year. Mortality rate, survivorship and thromboembolic events were not found to be associated with surgeon volume. We found a significant association between low surgeon volume and higher rate of infection (0.26% - 2.8% higher, procedure time (165 min versus 135 min, longer length of stay (0.4 - 2.13 days longer, transfusion rate (13% versus 4%, and worse patient reported outcomes. Conclusions Findings suggest a trend towards better outcomes for higher volume surgeons, but results must be interpreted with caution.

  18. LLE Review quarterly report, April--June 1993. Volume 55

    Energy Technology Data Exchange (ETDEWEB)

    Hutchison, R.J. [ed.

    1993-10-01

    This volume of the LLE Review, covering the period April--June 1993, contains articles on spectral features from argon-filled target implosions on OMEGA, and on the theory of an implicit difference scheme for the Fokker-Planck equation. The advanced technology section includes reports on a novel polymer liquid-crystal wave plate and a new scheme for phase conversion of the OMEGA Upgrade beams that results in greater, smoother energy deposition on fusion targets. Finally, reports on the as-designed configuration of the OMEGA newly configured glass development laser system are summarized.

  19. Human-system interface design review guideline -- Process and guidelines: Final report. Revision 1, Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    None

    1996-06-01

    NUREG-0700, Revision 1, provides human factors engineering (HFE) guidance to the US Nuclear Regulatory Commission staff for its: (1) review of the human system interface (HSI) design submittals prepared by licensees or applications for a license or design certification of commercial nuclear power plants, and (2) performance of HSI reviews that could be undertaken as part of an inspection or other type of regulatory review involving HSI design or incidents involving human performance. The guidance consists of a review process and HFE guidelines. The document describes those aspects of the HSI design review process that are important to the identification and resolution of human engineering discrepancies that could adversely affect plant safety. Guidance is provided that could be used by the staff to review an applicant`s HSI design review process or to guide the development of an HSI design review plan, e.g., as part of an inspection activity. The document also provides detailed HFE guidelines for the assessment of HSI design implementations. NUREG-0700, Revision 1, consists of three stand-alone volumes. Volume 1 consists of two major parts. Part 1 describes those aspects of the review process of the HSI design that are important to identifying and resolving human engineering discrepancies. Part 2 contains detailed guidelines for a human factors engineering review which identify criteria for assessing the implementation of an applicant`s or licensee`s HSI design.

  20. Volume transmission of beta-endorphin via the cerebrospinal fluid; a review

    Directory of Open Access Journals (Sweden)

    Veening Jan G

    2012-08-01

    Full Text Available Abstract There is increasing evidence that non-synaptic communication by volume transmission in the flowing CSF plays an important role in neural mechanisms, especially for extending the duration of behavioral effects. In the present review, we explore the mechanisms involved in the behavioral and physiological effects of β-endorphin (β-END, especially those involving the cerebrospinal fluid (CSF, as a message transport system to reach distant brain areas. The major source of β-END are the pro-opio-melano-cortin (POMC neurons, located in the arcuate hypothalamic nucleus (ARH, bordering the 3rd ventricle. In addition, numerous varicose β-END-immunoreactive fibers are situated close to the ventricular surfaces. In the present paper we surveyed the evidence that volume transmission via the CSF can be considered as an option for messages to reach remote brain areas. Some of the points discussed in the present review are: release mechanisms of β-END, independence of peripheral versus central levels, central β-END migration over considerable distances, behavioral effects of β-END depend on location of ventricular administration, and abundance of mu and delta opioid receptors in the periventricular regions of the brain.

  1. Ultra-low-volume space sprays in mosquito control: a critical review.

    Science.gov (United States)

    Bonds, J A S

    2012-06-01

    The availability of tools to control mosquito (Diptera:Culicidae) vectors that transmit disease is often limited by a variety of economic, environmental and social issues. In emergency conditions (epidemics, hurricanes, floods etc.), the application of pesticides as space sprays (either by ground or air) is the common method of choice in order to rapidly limit adult local mosquito production in the affected area. Space spray application now employs ultra-low-volume technology for the control of adult mosquitoes. However, the use of space sprays often raises social and environmental concerns by the general public that is served. This review will define and illustrate modern ultra-low-volume technology for the purpose of application as a space spray, as well as describing the engineering controls that have been developed to minimize the environmental impact. The primary social concern is validity and efficacy of application. To address this point, the review will attempt to synthesize the global literature to address the effectiveness of space sprays to significantly impact mosquito vectors in relation to human disease. © 2012 The Author. Medical and Veterinary Entomology © 2012 The Royal Entomological Society.

  2. Proceedings of the 1995 U.S. DOE hydrogen program review. Volume II

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    The 1995 US DOE Hydrogen Program Review was held April 18-21, 1995 in Coral Gables, FL. Volume II of the Proceedings contains 8 papers presented under the subject of hydrogen storage and 17 papers presented on hydrogen production. Selected papers are indexed separately for inclusion in the Energy Science and Technology Database.

  3. The Development and Application of the RAND Program Classification Tool. The RAND Toolkit, Volume 1

    Science.gov (United States)

    2014-01-01

    service, reference DoD programs related to psycho - logical health and TBI, but the R-PCT can be applied to other content areas or organizations. Table...and provides a high-level description, comparison, or classification of programs. Furthermore, given its simple architecture , the R-PCT can be

  4. Capsaicin on the viability of random-pattern skin flaps in rats Capsaicina na viabilidade de retalhos isquêmicos randômicos em ratos

    Directory of Open Access Journals (Sweden)

    Gustavo Roberto de Godoy

    2010-10-01

    Full Text Available PURPOSE: To evaluate the effects of capsaicin on the viability of ischemic random-pattern skin flaps in rats. METHODS:Forty EPM1-Wistar rats were randomized into two groups of 20 animals each, the capsaicin group and the control group. A random-pattern skin flap measuring 10 x 4cm was raised and a plastic barrier was placed between the flap and the donor site. After the surgical procedure, the control group was treated with an inert vehicle in the form of a cream applied uniformly to a rayon bandage which, in turn, was applied to the surface of the skin flap. The capsaicin group was treated in the same way, but in this case capsaicin was added to the cream. This procedure was repeated for two consecutive days. RESULTS: There was a significantly smaller amount of flap necrosis in the capsaicin group (35.07% than in the control group (44.75% (p=0.035. CONCLUSION:Topical administration of capsaicin improved the viability of ischemic random-pattern skin flaps in rats.OBJETIVO: Avaliar os efeitos da capsaicina na viabilidade de retalhos isquêmicos randômicos em ratos. MÉTODOS: Quarenta ratos EPM1-Wistar foram distribuídos ao acaso em dois grupos de 20 animais cada, um grupo capsaicina e um grupo controle. Um retalho isquêmico randômico medindo 10 x 4cm foi elevado e uma barreira plástica foi colocada entre o retalho e a área doadora. Após o procedimento cirúrgico, o grupo controle foi tratado com um veículo inerte sob a forma creme aplicado uniformemente sobre uma atadura de rayon, que, por sua vez, foi aplicada à superfície do retalho. O grupo capsaicina foi tratado da mesma forma, porém a capsaicina foi adicionada ao creme. Este procedimento foi repetido por dois dias consecutivos. RESULTADOS: Houve uma quantidade significativamente menor da necrose do retalho no grupo capsaicina (35,07% comparado ao grupo controle (44,75% (p=0,035. CONCLUSÃO: A administração tópica da capsaicina melhorou a viabilidade de retalhos isquêmicos rand

  5. Fat Injection: A Systematic Review of Injection Volumes by Facial Subunit.

    Science.gov (United States)

    Shue, Shirley; Kurlander, David E; Guyuron, Bahman

    2017-08-08

    Fat grafting to the aging face has become an integral component of esthetic surgery. However, the amount of fat to inject to each area of the face is not standardized and has been based mainly on the surgeon's experience. The purpose of this study was to perform a systematic review of injected fat volume to different facial zones. A systematic review of the literature was performed through a MEDLINE search using keywords "facial," "fat grafting," "lipofilling," "Coleman technique," "autologous fat transfer," and "structural fat grafting." Articles were then sorted by facial subunit and analyzed for: author(s), year of publication, study design, sample size, donor site, fat preparation technique, average and range of volume injected, time to follow-up, percentage of volume retention, and complications. Descriptive statistics were performed. Nineteen articles involving a total of 510 patients were included. Rhytidectomy was the most common procedure performed concurrently with fat injection. The mean volume of fat injected to the forehead is 6.5 mL (range 4.0-10.0 mL); to the glabellar region 1.4 mL (range 1.0-4.0 mL); to the temple 5.9 mL per side (range 2.0-10.0 mL); to the eyebrow 5.5 mL per side; to the upper eyelid 1.7 mL per side (range 1.5-2.5 mL); to the tear trough 0.65 mL per side (range 0.3-1.0 mL); to the infraorbital area (infraorbital rim to lower lid/cheek junction) 1.4 mL per side (range 0.9-3.0 mL); to the midface 1.4 mL per side (range 1.0-4.0 mL); to the nasolabial fold 2.8 mL per side (range 1.0-7.5 mL); to the mandibular area 11.5 mL per side (range 4.0-27.0 mL); and to the chin 6.7 mL (range 1.0-20.0 mL). Data on exactly how much fat to inject to each area of the face in facial fat grafting are currently limited and vary widely based on different methods and anatomical terms used. This review offers the ranges and the averages for the injected volume in each zone. This journal requires that authors assign a level of evidence

  6. LLE Review Quarterly Report (October - December 2007). Volume 113

    Energy Technology Data Exchange (ETDEWEB)

    Zuegel, Jonathan D. [Univ. of Rochester, NY (United States). Lab. for Laser Energetics

    2007-12-01

    This volume of the LLE Review, covering October–December 2007, features “High-Intensity Laser–Plasma Interactions in the Refluxing Limit,” by P. M. Nilson, W. Theobald, J. Myatt, C. Stoeckl, M. Storm, O. V. Gotchev, J. D. Zuegel, R. Betti, D. D. Meyerhofer, and T. C. Sangster. In this article (p. 1), the authors report on target experiments using the Multi-Terawatt (MTW) Laser Facility to study isochoric heating of solid-density targets by fast electrons produced from intense, short-pulse laser irradiation. Electron refluxing occurs due to target-sheath field effects and contains most of the fast electrons within the target volume. This efficiently heats the solid-density plasma through collisions. X-ray spectroscopic measurements of absolute Kα (x-radiation) photon yields and variations of the Kβ/Kα b emission ratio both indicate that laser energy couples to fast electrons with a conversion efficiency of approximately 20%. Bulk electron temperatures of at least 200 eV are inferred for the smallest mass targets.

  7. LLE Review Quarterly Report (January-March 2000). Volume 82

    Energy Technology Data Exchange (ETDEWEB)

    Radha, P. B. [Univ. of Rochester, NY (United States). Lab. for Laser Energetics

    2000-03-01

    This volume of the LLE Review, covering the period January-March 2000, includes a report on OMEGA cryogenic target designs for the soon-to-be-commissioned OMEGA Cryogenic Target Handling System. R. P. J. Town, J. A. Delettrez, R. Epstein, V. N. Goncharov, P. W. McKenty, P. B. Radha, and S. Skupsky use two-dimensional hydrodynamic simulations in conjunction with a stability analysis model to study the performance of OMEGA cryogenic capsules. They show that these targets are energy-scaled from the NIF ignition designs and have similar 1-D behavior and stability properties. This similarity will facilitate the extrapolation of cryogenic target studies on OMEGA to ignition targets on the NIF. Other articles in this volume are: Imprint Reduction using an Intensity Spike in Omega Cryogenic Targets; Measurement of Preheat Due to Fast Electrons in Laser Implosions; Holographic Transmission Gratings for Spectral Dispersion; Laser Beam Smoothing Caused by the Small-Spatial-Scale B-Integral; Three-Dimensional Modeling of Capsule Implosions in OMEGA Tetrahedral Hohlraums; and, Nanoindentation Hardness of Particles Used in Magnetoheological finishing (MRF).

  8. Starbucksfenomenet i Finland : Hur uppfattar och upplever finska konsumenter tillhörande generation Y och Z varumärket Starbucks?

    OpenAIRE

    Emtö, Anna

    2014-01-01

    I den här undersökningen har jag undersökt hur finska konsumenter uppfattar och upplever varumärket Starbucks. Jag har utfört undersökningen genom att använda mig av fokusgruppintervjuer. Intervjuerna utfördes på basen av min frågeguide som utvecklats kring de relevanta teoriområden som är presenterade i arbetet. Mitt urval för intervjuerna var finska konsumenter tillhörande generationerna Y och Z i och med att dessa vuxit upp med varumärket samt upplevt inflytandet av sociala medier i vardag...

  9. Proceedings of the advanced coal-fired power systems `95 review meeting, Volume II

    Energy Technology Data Exchange (ETDEWEB)

    McDaniel, H.M.; Mollot, D.J.; Venkataraman, V.K.

    1995-06-01

    This report contains papers which were presented at the advanced coal-fired power sytems review meeting. This is volume II. Topics include: hot gas filter issues, hazardous air pollutants, sorbent development, and separation technologies. Individual papers were processed separately for the United States Department of Energy databases.

  10. The relationship between patient volume and mortality in American trauma centres: a systematic review of the evidence.

    Science.gov (United States)

    Caputo, Lisa M; Salottolo, Kristin M; Slone, Denetta Sue; Mains, Charles W; Bar-Or, David

    2014-03-01

    To synthesise published and unpublished findings examining the relationship between institutional trauma centre volume or trauma patient volume per surgeon and mortality. Evidence on the relationship between patient volume and survival in trauma patients is inconclusive in the literature and remains controversial. A literature search was performed to identify studies published between 1976 and 2013 via MEDLINE (Pubmed) and the Cumulative Index to Nursing and Allied Health Literature (EbscoHost) as well as footnote chasing. Abstracts from appropriate conferences and ProQuest Dissertations and Theses were also searched. Inclusion criteria required studies to be original research published in English that examined the relationship between mortality and either institutional or per surgeon volume in American trauma centres. We employed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Statement checklist and flowchart. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach was employed to rate the quality of the evidence. Of 1392 studies reviewed, 19 studies met defined inclusion criteria; all studies were retrospective. The definition of volume was heterogeneous across the studies. Patient population and analysis methods also varied across the studies. Sixteen studies (84%) examined the relationship between institutional trauma centre volume and mortality. Of the 16 studies, 12 examined the volume of severely injured patients and eight examined overall trauma patient volume. High institutional volume was associated with at least somewhat improved mortality in ten of 16 studies (63%); however, nearly half of these studies found only some subpopulations experienced benefits. In the remaining six studies, volume was not associated with any benefits. Four studies (25%) analysed the impact of surgeon volume on mortality. High volume per surgeon was associated with improved mortality in only one of four studies

  11. LLE review. Quarterly report, April 1997--June 1997. Volume 71

    International Nuclear Information System (INIS)

    1997-01-01

    This volume of the LLE Review, covering the period April-June 1997, includes an article discussing the results from recent experiments performed on OMEGA. These experiments used a new beam-smoothing device-distributed polarization rotators-in concert with existing techniques to improve the on-target uniformity of each beam. The result of this improved radiation uniformity was a substantive reduction in imprinting-the nonuniformity caused by the laser. A novel way to study the time dependence of this imprinting is also presented in this article

  12. Improving Oversight and Coordination of Department of Defense Programs That Address Problematic Behaviors Among Military Personnel

    Science.gov (United States)

    2017-01-01

    Consider ways to leverage existing DoD data to continue to explore connections among problematic behaviors. Prevention strategies Review the effects that...Hepner, Targeting Alcohol Misuse: A Promising Strategy for Reducing Military Sexual Assaults? Santa Monica, Calif.: RAND Corporation , RR-538-OSD, 2014...and linking permissions, please visit www.rand.org/pubs/permissions. The RAND Corporation is a research organization that develops solutions to public

  13. Review of progress in quantitative nondestructive evaluation. Volume 8A and Volume 8B

    International Nuclear Information System (INIS)

    Thompson, D.O.; Chimenti, D.E.

    1989-01-01

    Volume 8 contains the edited papers presented at the 1988 Review of Progress in Quantitative Nondestructive Evaluation meeting. The 288 papers discuss such topics as fundamental techniques as acoustic testing, eddy current testing, and x-ray radiography; advanced techniques using x-ray computed tomography and laser ultrasonics; interpretive signal and image processing using expert systems and adaptive analysis; NDE probes and sensors and NDE systems and instrumentation; materials process control and inspection reliability including human factors. Materials discussed range from electronic circuit materials, coatings, adhesive bonds, smart structures, composite materials, welded joints, ferrous materials, and steels and alloys. Stress, texture, structural and fracture properties of materials are characterized using various NDE techniques. Applications to reactor, aircraft, and space vehicle components are investigated

  14. Validation of quality indicators for the organization of palliative care: a modified RAND Delphi study in seven European countries (the Europall project).

    Science.gov (United States)

    Woitha, Kathrin; Van Beek, Karen; Ahmed, Nisar; Jaspers, Birgit; Mollard, Jean M; Ahmedzai, Sam H; Hasselaar, Jeroen; Menten, Johan; Vissers, Kris; Engels, Yvonne

    2014-02-01

    Validated quality indicators can help health-care professionals to evaluate their medical practices in a comparative manner to deliver optimal clinical care. No international set of quality indicators to measure the organizational aspects of palliative care settings exists. To develop and validate a set of structure and process indicators for palliative care settings in Europe. A two-round modified RAND Delphi process was conducted to rate clarity and usefulness of a previously developed set of 110 quality indicators. In total, 20 multi-professional palliative care teams of centers of excellence from seven European countries. In total, 56 quality indicators were rated as useful. These valid quality indicators concerned the following domains: the definition of a palliative care service (2 quality indicators), accessibility to palliative care (16 quality indicators), specific infrastructure to deliver palliative care (8 quality indicators), symptom assessment tools (1 quality indicator), specific personnel in palliative care services (9 quality indicators), documentation methodology of clinical data (14 quality indicators), evaluation of quality and safety procedures (1 quality indicator), reporting of clinical activities (1 quality indicator), and education in palliative care (4 quality indicator). The modified RAND Delphi process resulted in 56 international face-validated quality indicators to measure and compare organizational aspects of palliative care. These quality indicators, aimed to assess and improve the organization of palliative care, will be pilot tested in palliative care settings all over Europe and be used in the EU FP7 funded IMPACT project.

  15. Modelling the rand and commodity prices: A Granger causality and cointegration analysis

    Directory of Open Access Journals (Sweden)

    Xolani Ndlovu

    2014-11-01

    Full Text Available This paper examines the ‘commodity currency’ hypothesis of the Rand, that is, the postulate that the currency moves in line with commodity prices, and analyses the associated causality using nominal data between 1996 and 2010. We address both the short run and long run relationship between commodity prices and exchange rates. We find that while the levels of the series of both assets are difference stationary, they are not cointegrated. Further, we find the two variables are negatively related, with strong and significant causality running from commodity prices to the exchange rate and not vice versa, implying exogeneity in the determination of commodity prices with respect to the nominal exchange rate. The strength of the relationship is significantly weaker than other OECD commodity currencies. We surmise that the relationship is dynamic over time owing to the portfolio-rebalance argument and the Commodity Terms of Trade (CTT effect and, in the absence of an error correction mechanism, this disconnect may be prolonged. For commodity and currency market participants, this implies that while futures and forward commodity prices may be useful leading indicators of future currency movements, the price risk management strategies may need to be recalibrated over time.

  16. LLE Review Quarterly Report (April-June 1996). Volume 67

    Energy Technology Data Exchange (ETDEWEB)

    Skeldon, Mark D. [Univ. of Rochester, NY (United States). Lab. for Laser Energetics

    1996-06-01

    This volume of the LLE Review, covering the period April-June 1996, contains articles detailing several nonlinear processes associated with lasers and their use, as well as an article describing the computer control systems necessary to maintain and operate a large laser system such as the 60-beam OMEGA laser. The specific topics discussed in this issue include stimulated scattering in laser plasmas, power exchange between interacting laser beams, charged particles interacting with a laser pulse, thermal equilibration of optically excited states, an overview of the laser control system software in OMEGA, and a technique for cancellation of the nonlinear phase accumulation in short-pulse lasers.

  17. Review of progress in the theory of volume production

    International Nuclear Information System (INIS)

    Hiskes, J.R.

    1986-01-01

    With the demonstration of large current densities extracted from hydrogen-discharge-type negative ion sources there has been a new emphasis directed toward the further development of these volume-type sources. Along with this emphasis has been a rapid increase in our understanding of the underlying atomic processes that occur in hydrogen-negative-ion discharges, together with a rapid evolution of the geometric configuration of these ion sources. An account of the development of the atomic processes in negative hydrogen discharges has been given in a recent review. Here we shall emphasize these atomic developments as they bear on the tandem high-density ion-source configuration. 32 refs., 10 figs

  18. Volume and health outcomes: evidence from systematic reviews and from evaluation of Italian hospital data.

    Science.gov (United States)

    Amato, Laura; Fusco, Danilo; Acampora, Anna; Bontempi, Katia; Rosa, Alessandro Cesare; Colais, Paola; Cruciani, Fabio; D'Ovidio, Mariangela; Mataloni, Francesca; Minozzi, Silvia; Mitrova, Zuzana; Pinnarelli, Luigi; Saulle, Rosella; Soldati, Salvatore; Sorge, Chiara; Vecchi, Simona; Ventura, Martina; Davoli, Marina

    2017-01-01

    BACKGROUND Improving quality and effectiveness of healthcare is one of the priorities of health policies. Hospital or physician volume represents a measurable variable with an impact on effectiveness of healthcare. An Italian law calls for the definition of «qualitative, structural, technological, and quantitative standards of hospital care». There is a need for an evaluation of the available scientific evidence in order to identify qualitative, structural, technological, and quantitative standards of hospital care, including the volume of care above or below which the public and private hospitals may be accredited (or not) to provide specific healthcare interventions. OBJECTIVES To identify conditions/interventions for which an association between volume and outcome has been investigated. To identify conditions/interventions for which an association between volume and outcome has been proved. To analyze the distribution of Italian health providers by volume of activity. To measure the association between volume of care and outcomes of the health providers of the Italian National Health Service (NHS). METHODS Systematic review An overview of systematic reviews was performed searching PubMed, EMBASE, and The Cochrane Library up to November 2016. Studies were evaluated by 2 researchers independently; quality assessment was performed using the AMSTAR checklist. For each health condition and outcome, if available, total number of studies, participants, high volume cut-off values, and metanalysis have been reported. According to the considered outcomes, health topics were classified into 3 groups: positive association: a positive association was demonstrated in the majority of studies/participants and/or a pooled measure (metanalysis) with positive results was reported; lack of association: both studies and/or metanalysis showed no association; no sufficient evidence of association: both results of single studies and metanalysis do not allow to draw firm conclusions

  19. Literature review of environmental qualification of safety-related electric cables: Literature analysis and appendices. Volume 2

    International Nuclear Information System (INIS)

    Lofaro, R.; Bowerman, B.; Carbonaro, J.

    1996-04-01

    In support of the US NRC Environmental Qualification (EQ) Research Program, a literature review was performed to identify past relevant work that could be used to help fully or partially resolve issues of interest related to the qualification of low-voltage electric cable. A summary of the literature reviewed is documented in Volume 1 of this report. In this, Volume 2 of the report, dossiers are presented which document the issues selected for investigation in this program, along with recommendations for future work to resolve the issues, when necessary. The dossiers are based on an analysis of the literature reviewed, as well as expert opinions. This analysis includes a critical review of the information available from past and ongoing work in thirteen specific areas related to EQ. The analysis for each area focuses on one or more questions which must be answered to consider a particular issue resolved. Results of the analysis are presented, along with recommendations for future work. The analysis is documented in the form of a dossier for each of the areas analyzed

  20. Compilation of reports of the Advisory Committee on Reactor Safeguards, 1957-1984. Volume 1. Project Reviews A-F

    International Nuclear Information System (INIS)

    1985-04-01

    This six-volume compilation contains over 1000 reports prepared by the Advisory Committee on Reactor Safeguards from September 1957 through December 1984. The reports are divided into two groups: Part 1: ACRS Reports on Project Reviews, and Part 2: ACRS Reports on Generic Subjects. Part 1 contains ACRS reports alphabetized by project name and within project name by chronological order. Part 2 categorizes the reports by the most appropriate generic subject area and within subject area by chronological order. This volume contains project reviews arranged alphabetically from A to F

  1. Radiologic measurement of extraocular muscle volumes in patients with Graves' orbitopathy: a review and guideline.

    Science.gov (United States)

    Bijlsma, Ward R; Mourits, Maarten Ph

    2006-06-01

    To evaluate and compare techniques for extraocular muscle (EOM) volume measurement and to provide guidelines for future measurements. Systematic review. Existing techniques used to measure extraocular muscle volumes on radiologic scans can be divided into manual outlining, computer assisted and automated segmentation. Both computed tomography (CT) and magnetic resonance (MR) image datasets can be used. On CT scans, one best measures muscle volume using region grow segmentation, accepting an overestimation of true volume by inevitable inclusion of non-muscular tissue. On high resolution MRI scans, single muscles can be outlined manually, but measurements include only part of the muscle due to poor tissue contrast at the orbital apex. Measurement errors can be reduced 3.5% by exact horizontal repositioning. A measured volume change of at least 6-17% is required to demonstrate a significant difference. Currently the best choice for EOM volume measurements on CT images is computer assisted grey value segmentation and on MRI images is manual outlining of individual muscles. Because of the time required and the complexity of the measurements, present EOM volume measurement is as yet only suitable for research purposes.

  2. Superconductivity Program for electric power systems: 1994 annual PEER review. Volume 1, Meeting proceedings

    International Nuclear Information System (INIS)

    1994-01-01

    This is Volume I of information presented at the Annual Peer Review of the Superconductivity Program For Electric Power Systems. Topics include: Wire development; powder synthesis; characterization of superconducting materials; electric power applications; magnetic refrigerators; and motor cooling issues. Individual reports were processed separately for the database

  3. LLE review. Volume 61, Quarterly report, October--December 1994

    International Nuclear Information System (INIS)

    1994-01-01

    This volume of the LLE review, covering the period of October--December 1994, contains articles on a diagnostic method employing krypton spectroscopy for measurement of temperature and shell-fuel mixing in high-temperature implosions; the first direct assessment of the ion-acoustic decay instability in a large-scale length, hot plasma; measurements of polarization mode dispersion and group-velocity walkaway in birefringent media using a frequency domain interferometer; an evaluation of the magnetic flux dynamics occurring in an optically triggered, thin-film superconducting switch; the effect of slurry fluid chemistry on particle size distribution during aqueous polishing of optical glass; and the influence of thermal and mechanical processing history in the preparation of well-ordered liquid crystal elastomer systems

  4. Low Tidal Volume versus Non-Volume-Limited Strategies for Patients with Acute Respiratory Distress Syndrome. A Systematic Review and Meta-Analysis.

    Science.gov (United States)

    Walkey, Allan J; Goligher, Ewan C; Del Sorbo, Lorenzo; Hodgson, Carol L; Adhikari, Neill K J; Wunsch, Hannah; Meade, Maureen O; Uleryk, Elizabeth; Hess, Dean; Talmor, Daniel S; Thompson, B Taylor; Brower, Roy G; Fan, Eddy

    2017-10-01

    Trials investigating use of lower tidal volumes and inspiratory pressures for patients with acute respiratory distress syndrome (ARDS) have shown mixed results. To compare clinical outcomes of mechanical ventilation strategies that limit tidal volumes and inspiratory pressures (LTV) to strategies with tidal volumes of 10 to 15 ml/kg among patients with ARDS. This is a systematic review and meta-analysis of clinical trials investigating LTV mechanical ventilation strategies. We used random effects models to evaluate the effect of LTV on 28-day mortality, organ failure, ventilator-free days, barotrauma, oxygenation, and ventilation. Our primary analysis excluded trials for which the LTV strategy was combined with the additional strategy of higher positive end-expiratory pressure (PEEP), but these trials were included in a stratified sensitivity analysis. We performed metaregression of tidal volume gradient achieved between intervention and control groups on mortality effect estimates. We used Grading of Recommendations Assessment, Development, and Evaluation methodology to determine the quality of evidence. Seven randomized trials involving 1,481 patients met eligibility criteria for this review. Mortality was not significantly lower for patients receiving an LTV strategy (33.6%) as compared with control strategies (40.4%) (relative risk [RR], 0.87; 95% confidence interval [CI], 0.70-1.08; heterogeneity statistic I 2  = 46%), nor did an LTV strategy significantly decrease barotrauma or ventilator-free days when compared with a lower PEEP strategy. Quality of evidence for clinical outcomes was downgraded for imprecision. Metaregression showed a significant inverse association between larger tidal volume gradient between LTV and control groups and log odds ratios for mortality (β, -0.1587; P = 0.0022). Sensitivity analysis including trials that protocolized an LTV/high PEEP cointervention showed lower mortality associated with LTV (nine trials and 1

  5. LLE review. Quarterly report, January 1994--March 1994, Volume 58

    Energy Technology Data Exchange (ETDEWEB)

    Simon, A. [ed.

    1994-07-01

    This volume of the LLE Review, covering the period Jan - Mar 1994, contains articles on backlighting diagnostics; the effect of electron collisions on ion-acoustic waves and heat flow; using PIC code simulations for analysis of ultrashort laser pulses interacting with solid targets; creating a new instrument for characterizing thick cryogenic layers; and a description of a large-aperture ring amplifier for laser-fusion drivers. Three of these articles - backlighting diagnostics; characterizing thick cryogenic layers; and large-aperture ring amplifier - are directly related to the OMEGA Upgrade, now under construction. Separate abstracts have been prepared for articles from this report.

  6. Book Reviews: Volume 8

    OpenAIRE

    2016-01-01

    Chris Frost Media Ethics and Self Regulation, reviewed by Michael Foley Damien Kiberd (ed.) Media in Ireland: The Search for Ethical Journalism, reviewed by David Quin Peter Mason and Derrick Smith Magazine Law: A Practical Guide, reviewed by Eavan Murphy

  7. Prerequisites concerning SSI:s review of applications for an encapsulation facility and a repository for spent nuclear fuel; Utgaangspunkter foer SSI:s granskning av ansoekan foer en inkapslingsanlaeggning och ett slutfoervar foer anvaent kaernbraensle

    Energy Technology Data Exchange (ETDEWEB)

    Oehlen, Elisabeth

    2006-09-15

    The report outlines some fundamental prerequisites concerning SSI:s review of SKB coming applications for an encapsulation facility (according to the act on nuclear activities) and for the complete final disposal system (according to the act on nuclear activities and the environmental code). The report summarize how the SSI look at the decision making process considering radiation protection requirements according to SSI:s regulations and general advices and earlier standpoints regarding SKB:s RandD-programme. The report also describe the present reviewing capacity of SSI and constitute therefore the basis for the planning of SSI:s review organisation in the prospect of coming applications on nuclear waste facilities (encapsulation facility and a deep disposal repository). It should be noted that the report reflects the present situation. Due to a number of factors as for example changes in SKB:s coming RandD-programme, future governmental decisions, adjustments of SSI:s financial resources or new facts in the case, will of course have an effect on how SSI finally will organise the review work. SSI:s home page will continuously be updated with the latest information in this respect.

  8. LLE Review Quarterly Report (October-December 2001). Volume 89

    Energy Technology Data Exchange (ETDEWEB)

    Donaldson, William R. [Univ. of Rochester, NY (United States). Lab. for Laser Energetics

    2001-12-01

    This volume of the LLE Review, covering October-December 2001, features “Time-Integrated Light Images of OMEGA Implosions” by P. Morley and W. Seka (p. 1). E. Kowaluk initiated this project for aesthetic rather than scientific reasons when he began taking visible light photographs of imploding OMEGA targets. These beautiful images are used to communicate LLE’s mission to the general public. A closer examination of the images revealed a one-to-one correspondence between the bright spots in the image and each of the 60 laser beams. The intensity of the bright spots has been related to refraction and absorption in the plasma surrounding the imploding target. These photographs are now proving to be the basis of a new laser-plasma interaction diagnostic. Other articles in this volume are titled the following: Analytical Model of Nonlinear, Single-Mode, Classical Rayleigh-Taylor Instability at Arbitrary Atwood Numbers; A High-Pass Phase Plate Design for OMEGA and the NIF; Advanced Tritium Recovery System; Establishing Links Between Single Gold Nanoparticles Buried Inside SiO2 Thin Film and 351-nm Pulsed-Laser-Damage Morphology; Resistive Switching Dynamics in Current-Biased Y-Ba-Cu-O Microbridges Excited by Nanosecond Electrical Pulses; and, Properties of Amorphous Carbon Films.

  9. Blood volume studies

    International Nuclear Information System (INIS)

    Lewis, S.M.; Yin, J.A.L.

    1986-01-01

    The use of dilution analysis with such radioisotopes as 51 Cr, 32 P, sup(99m)Tc and sup(113m)In for measuring red cell volume is reviewed briefly. The use of 125 I and 131 I for plasma volume studies is also considered and the subsequent determination of total blood volume discussed, together with the role of the splenic red cell volume. Substantial bibliography. (UK)

  10. Aldosterone Response in Severe Hypokalemia and Volume Depletion: A Case Report and Review of the Recent Research

    Directory of Open Access Journals (Sweden)

    Keiko Kai

    2016-01-01

    Full Text Available We report a case of severe hypokalemia and volume depletion complicated by chronic watery diarrhea resulting from chronic alcoholism in a 57-year-old man. Prompt replacement of normal saline with potassium chloride and cessation of alcohol intake resulted in a favorable outcome. We discuss the pathophysiology of the case, emphasizing the response of aldosterone in both hypokalemia and volume depletion, and provide a review of recent research.

  11. Defense Planning in a Time of Conflict: A Comparative Analysis of the 2001-2014 Quadrennial Defense Reviews, and Implications for the Army

    Science.gov (United States)

    2018-01-01

    these risks, nor did it explore the potential trade-offs required to execute the revised QDR strategy . It did, however, note that the portfolio of... Corporation , Santa Monica, Calif. © Copyright 2018 RAND Corporation R® is a registered trademark. Limited Print and Electronic Distribution Rights...commercial use. For information on reprint and linking permissions, please visit www.rand.org/pubs/permissions.html. The RAND Corporation is a research

  12. It is time to abandon "expected bladder capacity." Systematic review and new models for children's normal maximum voided volumes.

    Science.gov (United States)

    Martínez-García, Roberto; Ubeda-Sansano, Maria Isabel; Díez-Domingo, Javier; Pérez-Hoyos, Santiago; Gil-Salom, Manuel

    2014-09-01

    There is an agreement to use simple formulae (expected bladder capacity and other age based linear formulae) as bladder capacity benchmark. But real normal child's bladder capacity is unknown. To offer a systematic review of children's normal bladder capacity, to measure children's normal maximum voided volumes (MVVs), to construct models of MVVs and to compare them with the usual formulae. Computerized, manual and grey literature were reviewed until February 2013. Epidemiological, observational, transversal, multicenter study. A consecutive sample of healthy children aged 5-14 years, attending Primary Care centres with no urologic abnormality were selected. Participants filled-in a 3-day frequency-volume chart. Variables were MVVs: maximum of 24 hr, nocturnal, and daytime maximum voided volumes. diuresis and its daytime and nighttime fractions; body-measure data; and gender. The consecutive steps method was used in a multivariate regression model. Twelve articles accomplished systematic review's criteria. Five hundred and fourteen cases were analysed. Three models, one for each of the MVVs, were built. All of them were better adjusted to exponential equations. Diuresis (not age) was the most significant factor. There was poor agreement between MVVs and usual formulae. Nocturnal and daytime maximum voided volumes depend on several factors and are different. Nocturnal and daytime maximum voided volumes should be used with different meanings in clinical setting. Diuresis is the main factor for bladder capacity. This is the first model for benchmarking normal MVVs with diuresis as its main factor. Current formulae are not suitable for clinical use. © 2013 Wiley Periodicals, Inc.

  13. Developing appropriate criteria for Benign Prostatic Hyperplasia Surgery Using RAND Appropriateness Method (RAM

    Directory of Open Access Journals (Sweden)

    R Ostovar

    2009-07-01

    Full Text Available ABSTRACT: Introduction & Objective: Results of different studies show that a relatively large number of healthcare services offered are inappropriate or unnecessary. Benign prostatic hyperplasia is a benign enlargement of the prostate gland. Clinical features of this disease are one of the most common problems encountered by elderly males. The aim of this study was to assess the appropriateness of benign prostatic hyperplasia surgery. Materials & Methods: In this qualitative study which was conducted in 2008-9, in Tehran University of Medical Sciences, the RAN/UCLA method was used, which was designed in 1980 by the RAND institute and the University of California in Los Angeles. Regarding the stages of our method, scenarios and indications for benign prostatic hyperplasia surgery were chosen from the latest approved scientific resources and subsequently sent to urology specialists, who were chosen as members of the specialized panel. Panel members gave scores ranging from 1 to 9 to each indication and scenario based on scientific resources, clinical experiences and patient’s condition in two separate panel sessions. After compilation, the indications were finally grouped as appropriate, equivocal, and inappropriate so that they could be used to determine appropriateness of benign prostatic hyperplasia surgery in hospitals. In this study, the most suitable and most approved clinical guidelines related to benign prostatic hyperplasia, the Guidelines Evaluation and Research Appraisal (AGREE were used.The selected guidelines were used as scientific resources for choosing the indications of benign prostatic hyperplasia surgery. SPSS version 16 and kappa weighted value were used in analysis process of the study. Results: Out of 282 scenarios grouped as 9 conditions related to benign prostatic hyperplasia surgery, which were extracted from scientific sources, 73 cases (25.9% were considered as appropriate, 14 cases (5% as equivocal and 7 cases (2

  14. Alternative Measured-Service Rate Structures for Local Telephone Service,

    Science.gov (United States)

    1980-06-01

    contracts or grants . Views expressed in a Papet are the author’s own, and are not necessarily shared by Rand or its research sponsors. The Rand Corporation...by National Science Foundation, grant DAR 77-16286 to The Rand Corporation. Measuring costs depend strongly on the technology of the telephone network...a Budget Constraint. The Case of the Two-Part Tariff," Review of Economic Studies, July 1974, Vol. 41, pp. 337-345. -28- Oi, W. Y., "A Disneyland

  15. Prognostic value of epicardial fat volume measurements by computed tomography: a systematic review of the literature

    Energy Technology Data Exchange (ETDEWEB)

    Spearman, James V.; Krazinski, Aleksander W. [Medical University of South Carolina, Department of Radiology and Radiological Science, Charleston, SC (United States); Renker, Matthias [Medical University of South Carolina, Department of Radiology and Radiological Science, Charleston, SC (United States); Giessen University, Department of Internal Medicine I, Cardiology/Angiology, Giessen (Germany); Schoepf, U.J. [Medical University of South Carolina, Department of Radiology and Radiological Science, Charleston, SC (United States); Medical University of South Carolina, Division of Cardiology, Department of Medicine, Charleston, SC (United States); Herbert, Teri L. [Medical University of South Carolina, Department of Library Science and Informatics, Charleston, SC (United States); De Cecco, Carlo N. [Medical University of South Carolina, Department of Radiology and Radiological Science, Charleston, SC (United States); University of Rome ' Sapienza' - Polo Pontino, Department of Radiological Sciences, Oncology and Pathology, Latina (Italy); Nietert, Paul J. [Medical University of South Carolina, Department of Public Health Sciences, Charleston, SC (United States); Meinel, Felix G. [Medical University of South Carolina, Department of Radiology and Radiological Science, Charleston, SC (United States); Ludwig-Maximilians-University Hospital, Institute for Clinical Radiology, Munich (Germany)

    2015-11-15

    To perform a systematic review of the growing body of literature evaluating the prognostic value of epicardial fat volume (EFV) quantified by cross-sectional imaging. Two independent reviewers performed systematic searches on both PubMed and Scopus using search terms developed with a medical librarian. Peer-reviewed articles were selected based on the inclusion of outcome data, utilization of epicardial fat volume and sufficient reporting for analysis. A total of 411 studies were evaluated with nine studies meeting the inclusion criteria. In all, the studies evaluated 10,252 patients. All nine studies were based on CT measurements. Seven studies evaluated the prognostic value of EFV unadjusted for calcium score, and six of these studies found a significant association between EFV and clinical outcomes. Seven studies evaluated the incremental value of EFV beyond calcium scoring, and six of these studies found a significant association. The majority of studies suggest that EFV quantification is significantly associated with clinical outcomes and provides incremental prognostic value over coronary artery calcium scoring. Future research should use a binary cutoff of 125 mL for evaluation of EFV to provide consistency with other research. (orig.)

  16. The effect of economic downturn on the volume of surgical procedures: A systematic review.

    Science.gov (United States)

    Fujihara, Nasa; Lark, Meghan E; Fujihara, Yuki; Chung, Kevin C

    2017-08-01

    Economic downturn can have a wide range of effects on medicine at both individual and national levels. We aim to describe these effects in relation to surgical volume to guide future planning for physician specialization, patient expectations in the face of economic crises, or estimating healthcare expenditure. We hypothesized that because of high out-of-pocket costs, cosmetic procedure volumes would be most affected by economic decline. A systematic review was conducted using MEDLINE, Embase, and ABI/INFORMS. The main search terms were "economic recession" and "surgical procedures, operative". Studies were included if surgical volumes were measured and economic indicators were used as predictors of economic conditions. Twelve studies were included, and the most common subject was cosmetic (n = 5), followed by orthopedic (n = 2) and cardiac surgeries (n = 2). The majority of studies found that in periods of economic downturn, surgical volume decreased. Among the eight studies using Pearson's correlation analysis, there were no significant differences between cosmetic procedures and other elective procedures, indicating that cosmetic procedures may display trends similar to those of non-cosmetic elective procedures in periods of economic downturn. Surgical volume generally decreased when economic indicators declined, observed for both elective and non-elective surgery fields. However, a few specific procedure volumes such as vasectomy and caesarean section for male babies increased during the economic downturn. Knowledge of these trends can be useful for future surgical planning and distribution of healthcare resources. Copyright © 2017 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved.

  17. LLE Review Quarterly Report (April-June 1998). Volume 75

    Energy Technology Data Exchange (ETDEWEB)

    Epstein, Reuben [Univ. of Rochester, NY (United States). Lab. for Laser Energetics

    1998-06-01

    This volume of the LLE Review, covering the period April–June 1998, includes a report on a recent series of experiments, performed by A. Babushkin, M. Guardalben, R. Keck, and W. Seka, that demonstrate a new scheme for converting the infrared light of OMEGA to the third harmonic in the ultraviolet over a bandwidth that is significantly wider than has been previously attainable. This innovative scheme, employing a second tripling crystal in addition to the doubler-tripler pair currently in use, was proposed by D. Eimerl at Lawrence Livermore National Laboratory and adapted to the OMEGA system by S. Craxton and S. Oskoui, a recent participant in LLE’s Summer High-School Research Program. Wider bandwidths on OMEGA will allow the use of broadband beam smoothing with faster smoothing times than have been employed until now.

  18. A Review of the Effect of Injected Dextranomer/Hyaluronic Acid Copolymer Volume on Reflux Correction Following Endoscopic Injection

    Directory of Open Access Journals (Sweden)

    Sumit Dave

    2008-01-01

    Full Text Available The current literature suggests that multiple variables affect vesicoureteric reflux (VUR resolution rates following dextranomer/hyaluronic acid copolymer (Dx/HA injection. This article reviews the evidence pertaining to the effect of injected Dx/HA volume on success rates following endoscopic correction. Lack of prospective studies which use injected volume as a continuous variable coupled with a nonstandardized injection technique and endpoint hinders the ability to reach a definite conclusion.

  19. The Future of Health Care in the Kurdistan Region - Iraq: Toward an Effective, High-Quality System with an Emphasis on Primary Care.

    Science.gov (United States)

    Moore, Melinda; Anthony, C Ross; Lim, Yee-Wei; Jones, Spencer S; Overton, Adrian; Yoong, Joanne K

    2014-01-01

    At the request of the Kurdistan Regional Government (KRG), RAND researchers undertook a yearlong analysis of the health care system in the Kurdistan Region of Iraq, with a focus on primary care. RAND staff reviewed available literature on the Kurdistan Region and information relevant to primary care; interviewed a wide range of policy leaders, health practitioners, patients, and government officials to gather information and understand their priorities; collected and studied all available data related to health resources, services, and conditions; and projected future supply and demand for health services in the Kurdistan Region; and laid out the health financing challenges and questions. In this volume, the authors describe the strengths of the health care system in the Kurdistan Region as well as the challenges it faces. The authors suggest that a primary care-oriented health care system could help the KRG address many of these challenges. The authors discuss how such a system might be implemented and financed, and they make recommendations for better utilizing resources to improve the quality, access, effectiveness, and efficiency of primary care.

  20. The Importance of Habits in Meredith Rand and Shane Drinion’s ‘tête-à-tête’ in The Pale King

    Directory of Open Access Journals (Sweden)

    Alexander Moran

    2017-03-01

    Full Text Available This article utilises pragmatist philosopher John Dewey’s concept of habit to explore Wallace’s habit-based definition of character through a close reading of the long, confessional ‘tête-á-tête’ between Meredith Rand and Shane Drinion in 'The Pale King' (2011. Analysis of this scene shows the distinction between personal habits and societal customs, and the role of the observer in interpreting such habits and customs. A focus on habit demonstrates how Wallace advocates for a liberal democratic process of evolution and change. Dewey’s ideas are also shown to be a useful means to navigate the burgeoning field of Wallace Studies, and the habits and customs that have come to define the field.

  1. [Glass Development Laser (GDL) Facility upgrade.] LLE Review. Quarterly report, October-December 1984. Volume 21

    International Nuclear Information System (INIS)

    Kim, H.

    1984-01-01

    This volume of the LLE Review contains articles on the upgrade of the GDL (Glass Development) system, theoretical advances in the laser fusion effort, improved target fabrication capabilities, x-ray laser research, developments in the picosecond optics research of the LLE advanced technology program, and on the National Laser Users Facility activities for October-December 1984. 56 refs., 31 figs., 3 tabs

  2. Proceedings of the Advanced Turbine Systems Annual Program Review meeting. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-10-01

    Goal of the 8-year program is to develop cleaner, more efficient, and less expensive gas turbine systems for utility and industrial electric power generation, cogeneration, and mechanical drive units. The conference is held annually for energy executives, engineers, scientists, and other interested parties industry, academia, and Government. Advanced turbine systems topics discussed during five technical sessions included policy and strategic issues, program element overviews and technical reviews, related activities, university/industry consortium interactions, and supportive projects. Twenty-one papers presented during the technical sessions are contained in this volume; they are processed separately for the data base.

  3. The portfolio risk management and diversification benefits from the South African rand currency index (rain

    Directory of Open Access Journals (Sweden)

    F.Y. Jordaan

    2012-12-01

    Full Text Available This study attempts to explain the source of risk management and diversification benefits that investors may gain from the South African Rand Currency Index (RAIN as it relates to an equity portfolio with stock market exposure (locally or international. These diversification benefits may result from the negative correlation between RAIN and the South African All Share Index (ALSI. To explain and fully exploit the benefits of RAIN, the main variables that represent South Africa’s trading partner equity and bond markets movements, were identified. To account for the interaction of RAIN with the ALSI, the latter was firstly decomposed into its economic groups and secondly into its various sub-sectors. Various analyses were carried out to determine which variables describe the relationship between the ALSI and RAIN. The variables that describe the relationship with a high adjusted R2, were identified. The findings suggest that when the ALSI is decomposed into its ten economic groups and thirty-seven sub-groups, the quadratic as opposed to linear models using response surface regressions, explained the majority of the variation in RAIN over the entire period. The linear models, however, explained more of the variation in RAIN during the recent 2008/2009 financial crisis

  4. Ion Channels Involved in Cell Volume Regulation

    DEFF Research Database (Denmark)

    Hoffmann, Else Kay

    2011-01-01

    regulatory ion channels involved, and the mechanisms (cellular signalling pathways) that regulate these channels. Finally, I shall also briefly review current investigations in these two cell lines that focuses on how changes in cell volume can regulate cell functions such as cell migration, proliferation......This mini review outlines studies of cell volume regulation in two closely related mammalian cell lines: nonadherent Ehrlich ascites tumour cells (EATC) and adherent Ehrlich Lettre ascites (ELA) cells. Focus is on the regulatory volume decrease (RVD) that occurs after cell swelling, the volume...

  5. Promoting International Energy Security. Volume 1: Understanding Potential Air Force Roles

    Science.gov (United States)

    2012-01-01

    obtain additional information, contact Distribution Services: Telephone: (310) 451 -7002; Fax: (310) 451 -6915; Email: order@rand.org Library of...raise the temperature of one pound of water one degree Fahrenheit ) DoD Department of Defense EIA U.S. Energy Information Administration IEA International

  6. The effects of contrast media volume on acute kidney injury after transcatheter aortic valve replacement: a systematic review and meta-analysis.

    Science.gov (United States)

    Thongprayoon, Charat; Cheungpasitporn, Wisit; Podboy, Alexander J; Gillaspie, Erin A; Greason, Kevin L; Kashani, Kianoush B

    2016-11-01

    The goal of this systematic review was to assess the effects of contrast media volume on transcatheter aortic valve replacement-related acute kidney injury. A literature search was performed using Medline, EMbase, the Cochrane Database of Systematic Reviews, and clinicaltrials.gov from the inception of these databases through December 2015. Studies that reported relative risk, odds ratio, or hazard ratio comparing the risks of acute kidney injury following transcatheter aortic valve replacement in patients who received high contrast media volume were included. Pooled risk ratio (RR) and 95% confidence intervals (95% CI) were calculated using a random-effect, generic inverse variance method. Four cohort studies composed of 891 patients were included in the analyses to assess the risk of acute kidney injury after transcatheter aortic valve replacement in patients who received high contrast media volume. The pooled RR of acute kidney injury after transcatheter aortic valve replacement in patients who received a large volume of contrast media was 1.41 (95% CI, 0.87 to 2.28) compared with low contrast media volume. The meta-analysis was limited to studies using standard acute kidney injury definitions, and the pooled RR of acute kidney injury in patients who received high contrast media volume is 1.12 (95% CI, 0.78 to 1.62). Our meta-analysis shows no significant association between contrast media volume and risk of acute kidney injury after transcatheter aortic valve replacement. © 2016 Chinese Cochrane Center, West China Hospital of Sichuan University and John Wiley & Sons Australia, Ltd.

  7. Compilation of reports of the Advisory Committee on Reactor Safeguards, 1957-1984. Volume 3. Project Reviews Q-Z

    International Nuclear Information System (INIS)

    1985-04-01

    This six-volume compilation contains over 1000 reports prepared by the Advisory Committee on Reactor Safeguards from September 1957 through December 1984. The reports are divided into two groups: Part 1: ACRS Resports on Project Reviews, and Part 2: ACRS Reports on Generic Subjects. Part 1 contains ACRS reports alphabetized by project name and within project name by chronological order. Part 2 categorizes the reports by the most appropriate generic subject area and within subject area by chronological order. This volume includes reports arranged alpbabetically from Q to Z

  8. Status report. KfK contribution to the development of DEMO-relevant test blankets for NET/ITER. Pt. 1: Self-cooled liquid metal breeder blanket. Vol. 2. Detailed version

    International Nuclear Information System (INIS)

    John, H.; Malang, S.; Sebening, H.

    1991-12-01

    A self-cooled liquid metal breeder blanket for a fusion DEMO-reactor and the status of the development programme is described as a part of the European development programme of DEMO relevant test blankets for NET/ITER. Volume 1 (KfK 4907) contains a summary. Volume 2 (KfK 4908) a more detailed version of the report. Both volumes contain sections on previous studies on self-cooled liquid metal breeder blankets, the reference blanket design for a DEMO-reactor, a typical test blanket design including the ancillary loop system and the building requirements for NET/ITER together with the present status of the associated RandD-programme in the fields of neutronics, magnetohydrodynamics, tritium removal and recovery, liquid metal compatibility and purification, ancillary loop system, safety and reliability. An outlook is given regarding the required RandD-programme for the self-cooled liquid metal breeder blanket prior to tests in NET/ITER and the relevant test programme to be performed in NET/ITER. (orig.) [de

  9. Impact of partial-volume correction in oncological PET studies. A systematic review and meta-analysis

    Energy Technology Data Exchange (ETDEWEB)

    Cysouw, Matthijs C.F.; Kramer, Gerbrand M.; Hoekstra, Otto S. [VU University Medical Centre, Department of Radiology and Nuclear Medicine, Amsterdam (Netherlands); Schoonmade, Linda J. [VU University Medical Centre, Department of Medical Library, Amsterdam (Netherlands); Boellaard, Ronald [VU University Medical Centre, Department of Radiology and Nuclear Medicine, Amsterdam (Netherlands); University Medical Centre Groningen, Department of Nuclear Medicine and Molecular Imaging, Groningen (Netherlands); Vet, Henrica C.W. de [VU University Medical Centre, Department of Epidemiology and Biostatistics, Amsterdam (Netherlands)

    2017-11-15

    Positron-emission tomography can be useful in oncology for diagnosis, (re)staging, determining prognosis, and response assessment. However, partial-volume effects hamper accurate quantification of lesions <2-3 x the PET system's spatial resolution, and the clinical impact of this is not evident. This systematic review provides an up-to-date overview of studies investigating the impact of partial-volume correction (PVC) in oncological PET studies. We searched in PubMed and Embase databases according to the PRISMA statement, including studies from inception till May 9, 2016. Two reviewers independently screened all abstracts and eligible full-text articles and performed quality assessment according to QUADAS-2 and QUIPS criteria. For a set of similar diagnostic studies, we statistically pooled the results using bivariate meta-regression. Thirty-one studies were eligible for inclusion. Overall, study quality was good. For diagnosis and nodal staging, PVC yielded a strong trend of increased sensitivity at expense of specificity. Meta-analysis of six studies investigating diagnosis of pulmonary nodules (679 lesions) showed no significant change in diagnostic accuracy after PVC (p = 0.222). Prognostication was not improved for non-small cell lung cancer and esophageal cancer, whereas it did improve for head and neck cancer. Response assessment was not improved by PVC for (locally advanced) breast cancer or rectal cancer, and it worsened in metastatic colorectal cancer. The accumulated evidence to date does not support routine application of PVC in standard clinical PET practice. Consensus on the preferred PVC methodology in oncological PET should be reached. Partial-volume-corrected data should be used as adjuncts to, but not yet replacement for, uncorrected data. (orig.)

  10. Developing Criteria for Lumbar Spine Magnetic Resonance Imaging (MRI) Using RAND Appropriateness Method (RAM)

    International Nuclear Information System (INIS)

    Keshtkaran, Ali; Bagheri, Mohammad Hadi; Ostovar, Rahim; Salari, Hedayat; Farokhi, Majid Reza; Esfandiari, Atefeh; Yousefimanesh, Hossein

    2012-01-01

    Studies show that a large proportion of healthcare offered may be inappropriate or unnecessary. Magnetic resonance imaging (MRI) is a new and expensive diagnostic technology which has been increasingly used all over the world. Moreover, this trend has been more rapidly increasing in Iran. Low back pain is a common disorder all over the world and MRI technique is one of the several ways to assess its cause. The present study aims to develop scenarios for lumbar spine MRI. In the present study, the RAND Appropriateness Method (RAM) was used in order to reach consensus regarding developing scenarios for lumbar spine MRI. We generated scenarios from valid clinical guidelines as well as the experts’ opinion. The panel members included nine specialists from various medical specialties that had scored scenarios in two rounds, the first of which was without interaction, while the second one was with interaction. We extracted 97 scenarios for the lumbar spine MRI in the scenario extracting phase of the study and the panel members added 18 scenarios. After implementation of two rounds, the scenarios were categorized into three ranges. Sixty seven (58%) of the scenarios were considered as appropriate, 45 (39%) as uncertain, and three (2.6%) as inappropriate. RAM is useful for identifying stakeholder views in settings with limited resources. Since RAM has precise instructions for consensus developing, a large number of scenarios were considered as uncertain. Therefore, more research has to be conducted on the issue

  11. 'Syncing' Up with the Quinn-Rand-Strogatz Constant: Hurwitz-ZetaFunctions in Non-Linear physics

    Energy Technology Data Exchange (ETDEWEB)

    Durgin, Natalie J.; Garcia, Sofia M.; Flournoy, Tamara; Bailey,David H.

    2007-12-01

    This work extends the analytical and computationalinvestigation of the Quinn-Rand-Strogatz (QRS) constants from non-linearphysics. The QRS constants (c1, c2, ..., cN) are found in a Winfreeoscillator mean-field system used to examine the transition of coupledoscillators as they lose synchronization. The constants are part of anasymptotic expansion of a function related to the oscillatorsynchronization. Previous work used high-precision software packages toevaluate c1 to 42 decimal-digits, which made it possible to recognize andprove that c1 was the root of a certain Hurwitz-zeta function. Thisallowed a value of c2 to beconjectured in terms of c1. Therefore thereis interest in determining the exact values of these constants to highprecision in the hope that general relationships can be establishedbetween the constants and the zeta functions. Here, we compute the valuesof the higher order constants (c3, c4) to more than 42-digit precision byextending an algorithm developed by D.H. Bailey, J.M. Borwein and R.E.Crandall. Several methods for speeding up the computation are exploredand an alternate proof that c1 is the root of a Hurwitz-zeta function isattempted.

  12. Healthcare service delivery: a literature review

    CSIR Research Space (South Africa)

    Arhete, LE

    2016-05-01

    Full Text Available African government is in the process of implementing a multibillion rand national health insurance (NHI) programme intended to revamp the entire national health system to among others, ensure affordability and accessibility to healthcare. The purpose...

  13. LLE Review Quarterly Report (July-September 1998). Volume 76

    Energy Technology Data Exchange (ETDEWEB)

    Epstein, Reuben [Univ. of Rochester, NY (United States). Lab. for Laser Energetics

    1998-09-01

    This volume of the LLE Review, covering the period July-September 1998, includes reports on two of the newest subsystems in the OMEGA laser facility. A. V. Okishev, M. D. Skeldon, and W. Seka have developed a highly stable, diode-pumped Nd:YLF master oscillator for the OMEGA laser system. This new master oscillator produces either single-frequency Q-switched pulses or cw radiation for the OMEGA pulse-shaping system. The switch-over between these two regimes requires no laser realignment. The new master oscillator is completely computer controlled and has been operating continuously in OMEGA for six months without operator intervention. A. Babushkin, W. Bittle, S. A. Letzring, M. D. Skeldon, and W. Seka have designed a negative-feedback–controlled regenerative amplifier that has been part of the OMEGA laser system for the past two years. The negative feedback makes the energy output of the regenerative amplifier stable and insensitive to the variations in pulse energy. This amplifier’s long-term output energy stability is the highest ever demonstrated for a millijoule-level laser system, either flashlamp pumped or diode pumped. Other articles in this volume are titled: Transcient Bandwidth Analysis of Photoconductive Microwave Switches Implemented in the OMEGA Pulse-Shaping System; Simulations of Near-Field Intensity Modulations in High-Intensity Laser Beams due to Self- and Cross-Phase Modulation Between Orthogonally Polarized Laser Beams Emerging from a Diamond-Turned KDP Wedge; X-Ray Radiographic System Used to Measure the Evolution of Broadband Imprint in Laser-Driven Planar Targets; Collisionless Damping of Localized Plasma Waves in Laser-Produces Plasmas and Application to Stimulated Raman Scattering in Filaments; LLE's Summer High School Research Program; FY98 Laser Facility Report; and, National Laser Users' Facilty News.

  14. Proceedings of the 1998 U.S. DOE Hydrogen Program Review: Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-08-01

    This document contains technical progress reports on 42 research projects funded by the DOE Hydrogen Program in Fiscal Year 1998, in support of its mission to make hydrogen a cost-effective energy carrier for utility, building, and transportation applications. Each year, the Program conducts a rigorous review of its portfolio of projects, utilizing teams of experts to provide vital feedback on the progress of research. These proceedings serve as an important technology reference for the DOE Hydrogen Program. The papers in Volume 2 are arranged under the following topical sections: Storage and separation systems; Thermal systems; and Transportation systems. Selected papers have been indexed separately for inclusion in the Energy Science and Technology Database.

  15. Review

    NARCIS (Netherlands)

    Wilde, de W.J.J.O.

    1994-01-01

    This review marks the appearance of Volume II, after the publication of Volume I, Pteridophytes and Gymnosperms, in 1990; several more volumes are expected in the future before completion of the Vascular plants as a whole. The present volume contains 73 families out of some 250-500 families which

  16. Command History 1970. Volume 3. Sanitized

    Science.gov (United States)

    1970-01-01

    Z30th NVA Trans Regt, left 16 KIA. Two days later 17 krn southwest of Khan Duc , ealments of the 6th ARVN Rert killed 20 enemy In a brief contact without...they intended to project. First, on 21 Apr Troung Chinh , Chairman of the National Assembly in North Vietnam, announced that Vietnam. Laos, rand...operations. Operation TRAN HUNG DAO XI (C) At 0730H on 9 May, a joint American and Vietnamese task force swept up the Mekong River into Cambodia. The

  17. When high-volume PCI operators in high-volume hospitals move to lower volume hospitals-Do they still maintain high volume and quality of outcomes?

    Science.gov (United States)

    Lu, Tsung-Hsueh; Li, Sheng-Tun; Liang, Fu-Wen; Lee, Jo-Chi; Yin, Wei-Hsian

    2017-10-31

    The aim of this quasi-experimental study was to examine whether high-volume percutaneous coronary intervention (PCI) operators still maintain high volume and quality of outcomes when they moved to lower volume hospitals. Systematic reviews have indicated that high-volume PCI operators and hospitals have higher quality outcomes. However, little is known on whether high PCI volume and high quality outcomes are mainly due to operator characteristics (i.e., skill and experience) and is portable across organizations or whether it is due to hospital characteristics (i.e., equipment, team, and management system) and is less portable. We used Taiwan National Health Insurance claims data 2000-2012 to identify 98 high-volume PCI operators, 10 of whom moved from one hospital to another during the study period. We compared the PCI volume, risk-adjusted mortality ratio, and major adverse cardiovascular event (MACE) ratio before and after moving. Of the 10 high-volume operators who moved, 6 moved from high- to moderate- or low-volume hospitals, with median annual PCI volumes (interquartile range) of 130 (117-165) in prior hospitals and 54 (46-84) in subsequent hospitals (the hospital the operator moved to), and the remaining 4 moved from high to high-volume hospitals, with median annual PCI volumes (interquartile range) of 151 (133-162) in prior hospitals and 193 (178-239) in subsequent hospitals. No significant differences were observed in the risk-adjusted mortality ratios and MACE ratios between high-volume operators and matched controls before and after moving. High-volume operators cannot maintain high volume when they moved from high to moderate or low-volume hospitals; however, the quality of care is maintained. High PCI volume and high-quality outcomes are less portable and more hospital bound. © 2017 Wiley Periodicals, Inc.

  18. 76 FR 40685 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2011-07-11

    ... access to respondent-level information. This increases the value of data that has been collected. Access..., Peterson Institute for International Economics, Rand Corporation, Public Policy Institute of California...

  19. The RAND Online Measure Repository for Evaluating Psychological Health and Traumatic Brain Injury Programs. The RAND Toolkit, Volume 2

    Science.gov (United States)

    2014-01-01

    tempo may raise the risk for mental health challenges. During this time, the U.S. Department of Defense (DoD) has implemented numerous programs to...and were based on the constraints of each electronic database. However, most searches were variations on a basic three-category format: The first...Gerontology, 1983, 38: 111–116. Iannuzzo RW, Jaeger J, Goldberg JF, Kafantaris V, Sublette ME. “Development and Reliability of the Ham-D/MADRS

  20. The impact of environmental conditions on human performance: A critical review of the literature. Volume 2

    International Nuclear Information System (INIS)

    Echeverria, D.; Barnes, V.; Bittner, A.

    1994-09-01

    The Battelle Human Affairs Research Centers (HARC) conducted a comprehensive review of the technical literature regarding the impact of environmental conditions on human performance applicable to nuclear power plant workers. The environmental conditions considered were vibration, noise, heat, cold, and light. Research staff identified potential human performance deficits along a continuum of increasing occupational exposure, ranging from deficits that occur at low exposures to deficits that occur at high exposures. Specific deficits were included in the review if scientists demonstrated the exposure caused an effect, using sound methodology. The levels associated with each deficit were then compared to the protection afforded by existing occupational exposure standards. Volume 2 presents several conclusions regarding the applicability of the research literature to environmental conditions in nuclear power plants. The findings presented suggest that occupational standards for vibration, noise, and heat, which were developed to protect health, are inadequate for preventing deficits in cognitive or motor performance in tasks likely to be performed in nuclear power plants. Also, there is little information in the literature on simultaneous conditions; for example, the effects of simultaneous exposure to heat and noise on cognition require more research. As many exposures in nuclear power plants will be simultaneous, this limitation should be kept in mind when using Volume 1

  1. LLE Review Quarterly Report (July - September 2004). Volume 100

    Energy Technology Data Exchange (ETDEWEB)

    Schmid, Ansgar W. [Univ. of Rochester, NY (United States). Lab. for Laser Energetics

    2004-09-01

    The key article in this volume of the LLE Review, covering July-September 2004, addresses "Shock Propagation in Deuterium-Tritium-Saturated Foam" by T. J. B. Collins (LLE) and A. Poludnenko, A. Cunningham, and A. Frank (UR, Department of Physics and Astronomy) (p. 227). Testing the assumption of homogeneous mixing in fibrous foams saturated with cryogenic deuterium and tritium, shock passage in wetted-foam mixtures was simulated by the adaptive-mesh, two-dimensional hydrodynamic code AstroBEAR. For foam fibers of diameter ~1/10 µm and relevant foam densities, the mixing length behind the shock is found to be of the order of microns. Transverse motion dampens out sufficiently that, at the mixing region's edge farthest from the shock, Rankine-Hugoniot jump conditions are obeyed to within a few percent and shock speeds are also within a few percent of their homogeneous values. In addition, questions of feedthrough and feedout are addressed, showing that the stability of the shock front, once it leaves the wetted-foam layer, minimizes the effect of feedthrough. As a result, simulations of whole-foam-pellet implosions may model the wetted foam as a homogeneous mixture.

  2. Lower vs. higher fluid volumes in sepsis-protocol for a systematic review with meta-analysis

    DEFF Research Database (Denmark)

    Meyhoff, T S; Møller, M H; Hjortrup, P B

    2017-01-01

    sequential analysis of randomised clinical trials comparing different strategies to obtain separation in fluid volumes or balances during resuscitation of adult patients with sepsis. We will systematically search the Cochrane Library, MEDLINE, EMBASE, Science Citation Index, BIOSIS and Epistemonikos...... for relevant literature. We will follow the recommendations by the Cochrane Collaboration and the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) statement. The risk of systematic errors (bias) and random errors will be assessed, and the overall quality of evidence will be evaluated...

  3. Review article: volume expansion in patients with cirrhosis

    DEFF Research Database (Denmark)

    Henriksen, Jens Henrik Sahl; Kiszka-Kanowitz, Marianne; Bendtsen, Flemming

    2002-01-01

    with low systemic vascular resistance, increased whole-body vascular compliance, and increased arterial compliance. The effectiveness and temporal relations of plasma/blood volume expansion depend highly on the type of load (water, saline, oncotic material, red blood cells). Patients with cirrhosis respond...... in advanced cirrhosis is qualitatively and quantitatively different from that of healthy subjects, and in those with early cirrhosis. Timely handling is essential, but difficult as it is a balance between the risks of excess extravascular volume loading and further circulatory dysfunction in these patients...

  4. Radiation damage effects in solids special topic volume with invited peer reviewed papers only

    CERN Document Server

    Virk, Hardev Singh

    2013-01-01

    Public interest and concern about radiation damage effects has increased during recent times. Nuclear radiation proved to be a precursor for the study of radiation damage effects in solids. In general, all types of radiation, e.g. X-ray, gamma ray, heavy ions, fission fragments and neutrons produce damage effects in materials. Radiation damage latent tracks in solids find applications in nuclear and elementary particle physics, chemistry, radiobiology, earth sciences, nuclear engineering, and a host of other areas such as nuclear safeguards, virus counting, ion track filters, uranium exploration and archaeology. Radiation dosimetry and reactor shielding also involve concepts based on radiation damage in solids. This special volume consists of ten Chapters, including Review and Research Papers on various topics in this field.Physical scientists known to be investigating the effects of radiation on material were invited to contribute research and review papers on the areas of their specialty. The topics include...

  5. [Experiments on the OMEGA Laser System]. LLE Review. Quarterly report, July-September 1985. Volume 24

    International Nuclear Information System (INIS)

    Skupsky, S.

    1985-01-01

    This volume of the LLE Review contains articles on the first 24-beam uv experiments on the OMEGA laser system, the use of absorption spectroscopy to diagnose high-density compressions, the development of a new target fabrication technique to coat mechanically unsupported laser-fusion targets with a parylene layer, the use of liquid crystals as laser-beam apodizers, the investigation of the process of melting using a subpicosecond probe, the development of a new picosecond oscilloscope, and the National Laser Users Facility activities for June-September 1985. 80 refs., 36 figs

  6. Reviews

    NARCIS (Netherlands)

    Adema, Frits

    1995-01-01

    This is the second volume of a revision of Tabernaemontana (Apocynaceae). The volume covers the New World species (44) and the genus Stemmadenia (10 species). This part of the revision of Tabernaemontana comes up to the high standards set in the first volume [see the review by Leenhouts, Blumea 38

  7. Military Review, December 1991. Volume 71, Volume 12

    Science.gov (United States)

    1991-12-01

    than 2 hours, 353 Japanese planes broke the 94 December 1991 * MILITARY REVIEW WWII ALMANAC spine of the Pacific Fleet by sinking or seriously dam... hedgehog defenses kov’s Western Front, with a combat strength of across the front and caught in encirclements of up to 388,000 men and 550 tanks

  8. Balancing Demand and Supply for Veterans' Health Care: A Summary of Three RAND Assessments Conducted Under the Veterans Choice Act.

    Science.gov (United States)

    Farmer, Carrie M; Hosek, Susan D; Adamson, David M

    2016-06-20

    In response to concerns that the Department of Veterans Affairs (VA) has faced about veterans' access to care and the quality of care delivered, Congress enacted the Veterans Access, Choice, and Accountability Act of 2014 ("Veterans Choice Act") in August 2014. The law was passed to help address access issues by expanding the criteria through which veterans can seek care from civilian providers. In addition, the law called for a series of independent assessments of the VA health care system across a broad array of topics related to the delivery of health care services to veterans in VA-owned and -operated facilities, as well as those under contract to VA. RAND conducted three of these assessments: Veteran demographics and health care needs (A), VA health care capabilities (B), and VA authorities and mechanisms for purchasing care (C). This article summarizes the findings of our assessments and includes recommendations from the reports for improving the match between veterans' needs and VA's capabilities, including VA's ability to purchase necessary care from the private sector.

  9. Amgold: 49. Annual report to February 28 1986

    International Nuclear Information System (INIS)

    1986-01-01

    The annual report of the Anglo American Gold Investment Company gives a listing of the group's investments and a review of principle interests. A short review is given on the activities and financial position of each of the gold mines in the Orange Free State, the Near East Rand, the Far West Rand and the Klerksdorp area. Information on uranium production is also given. Supplies of new production of uranium continued to decline in all major uranium-producing countries. Continuing increases in utility requirements have steadied the uranium market. Statistics are given on the profits made and the production of uranium in South Africa

  10. Rectal cancer surgery: volume-outcome analysis.

    LENUS (Irish Health Repository)

    Nugent, Emmeline

    2010-12-01

    There is strong evidence supporting the importance of the volume-outcome relationship with respect to lung and pancreatic cancers. This relationship for rectal cancer surgery however remains unclear. We review the currently available literature to assess the evidence base for volume outcome in relation to rectal cancer surgery.

  11. LLE review. Quarterly report, October--December 1991: Volume 49

    Energy Technology Data Exchange (ETDEWEB)

    Keck, R.L. [ed.

    1991-12-31

    This volume of the LLE Review, covering the period October-December 1991, contains articles on the analysis of argon-filled target experiments, and a theoretical analysis of the impact of nonlocal heat transport in laser filamentation in plasmas. In the Advanced Technology section there is an article on mechanisms that affect thin-film conductivity, and a report on the gain characteristics of the 20-cm SSA prototype amplifier to be used in the OMEGA Upgrade. Finally, the activities of the National Laser Users Facility and the GDL and OMEGA laser facilities are summarized. Highlights of the research reported in this issue are: argon radiation from argon-filled, polymer-shell targets is used as a core-temperature diagnostic and density diagnostic of the surrounding region in a regime where the argon line radiation is strongly absorbed. A theoretical analysis of the impact of nonlocal heat transport on laser filamentation in plasmas is developed. The resulting model is compared with experimental observations and the implications for ICF are discussed. A study of thermal conductivity in thin films seeks to identify mechanisms that result in degradation of thin-film conductivity. Identifying these mechanisms can lead to changes in the thin-film manufacture that will improve their resistance to laser damage.

  12. Electroanalytical chemistry. Volume 14

    International Nuclear Information System (INIS)

    Bard, A.J.

    1986-01-01

    This volume is part of a series aimed at authoritative reviews of electroanalytical techniques and related areas of investigation. Volume 14 clearly maintains the high standards and proven usefulness of the series. Topics covered include conformation change and isomerization associated with electrode reactions, infrared vibrational spectroscopy of the electrode-solution interface, and precision in linear sweep and cyclic voltametry. A short history of electrochemical techniques which include the term square wave is provided

  13. Topical report review status: Volume 10

    International Nuclear Information System (INIS)

    1996-03-01

    This report provides industry with procedures for submitting topical reports, guidance on how the U.S. Nuclear Regulatory Commission (NRC) processes and responds to topical report submittals, and an accounting, with review schedules, of all topical reports currently accepted for review by the NRC. This report is published annually

  14. Defense Planning In A Time Of Conflict: A Comparative Analysis Of The 2001-2014 Quadrennial Defense Reviews, And Implications For The Army--Executive Summary

    Science.gov (United States)

    2018-01-01

    the opinions of its research clients and sponsors. Support RAND Make a tax -deductible charitable contribution at www.rand.org/giving/contribute...each QDR, including assessments from the U.S. Government Accountability Office, the Congressional Budget Office, the Congressional Research Service...cuts in modernization, readiness, and other accounts . Force Planning To assist in planning the FY19 force structure, the 2014 QDR assessed the

  15. LLE Review. Volume 68, July--September 1996

    International Nuclear Information System (INIS)

    1996-07-01

    This volume of the LLE Review, covering the period of July-September 1996, includes a description of an important experiment carried out on OMEGA by researchers from LANL, LLNL, and LLE to demonstrate the feasibility of using OMEGA for indirect drive. Additional topics include tetrahedral hohlraums, the speckle properties of phase- converted laser beams, design criteria for SSD phase modulators, and the design of slab amplifiers. Highlights of the research presented in this issue are (1) Results from the proof-of-principle indirect- drive experiments in which up to 40 OMEGA beams were used to irradiate cylindrical hohlraums. Nova results were reproduced, and new capabilities not available on other lasers were demonstrated. (2) A discussion of tetrahedral hohlraums (spherical hohlraums with four laser entrance holes) as a means of achieving better capsule irradiation uniformity. Tetrahedral hohlraums also allow the use of all 60 OMEGA beams and may provide an alternate route to ignition on the NIF. (3) An analysis of the residual target irradiation nonuniformity due to the fine laser speckle remaining on the beam after being phase converted by the DPP's. A model shows how a uniformly ablating plasma atmosphere reduces the speckle contribution to the effective time-averaged irradiation nonuniformity. (4) A discussion of the theory, design, manufacture, testing, and implementation of the microwave SSD phase modulators used on OMEGA for two-dimensional SSD. The modulators are capable of operating in the gigahertz frequency range. (5) A discussion of the design and performance of a large-aperture, high-gain Nd:glass zig-zag slab amplifier for materials testing. The design incorporates improvements from previous work in addition to improvements obtained from careful design choices guided by analytic calculations

  16. Proceedings of the symposium to review Volume III of the Annual Report to Congress

    Energy Technology Data Exchange (ETDEWEB)

    Alt, F.; Norland, D.

    1979-01-01

    This report is a transcript of the proceedings of a two-day Symposium, held in the Fall of 1979 at the University of Maryland in order to independently review the 1978 Energy Information Administration (EIA) Annual Report to Congress (ARC), Volume III. Participants included energy forecasting experts from the academic community and the private sector; other Federal, State, and local government energy experts; and Office of Applied Analysis, EIA, staff members. The Symposium and its transcript are a critique of the underlying 1978 ARC assumptions, methodologies, and energy system projections. Discussions cover the short-, mid-, and long-term periods, national and international forecasts, source and consuming sectors and projected economic impacts. 27 figures, 22 tables.

  17. Report of the Survey on the Design Review of New Reactor Applications. Volume 1 - Instrumentation and Control

    International Nuclear Information System (INIS)

    Downey, Steven

    2014-06-01

    At the tenth meeting of the CNRA Working Group on the Regulation of New Reactors (WGRNR) in March 2013, the members agreed to present the responses to the Second Phase, or Design Phase, of the Licensing Process Survey as a multi-volume text. As such, each report will focus on one of the eleven general technical categories covered in the survey. The general technical categories were selected to conform to the topics covered in the International Atomic Energy Agency (IAEA) Safety Guide GS-G-4.1. This report, which is the first volume, provides a discussion of the survey responses related to Instrumentation and Control (I and C). The Instrumentation and Control category includes the twelve following technical topics: Reactor trip system, actuation systems for Engineered Safety Features (ESF), safe shutdown system, safety-related display instrumentation, information and interlock systems important to safety, controls systems, main control room, supplementary control room, diverse I and C systems, data communication systems, software reliability and cyber-security. For each technical topic, the member countries described the information provided by the applicant, the scope and level of detail of the technical review, the technical basis for granting regulatory authorisation, the skill sets required and the Level of effort needed to perform the review. Based on a comparison of the information provided in response to the survey, the following observations were made: - Among the regulatory organisations that responded to the survey, there are similarities in the design information provided by an applicant. In most countries, the design information provided by an applicant includes, but is not limited to, a description of the I and C system design and functions, a description of the verification and validation programmes, and provisions for analysis, testing, and inspection of various I and C systems. - In addition to the regulations, it is a common practice for countries

  18. Complex-wide review of DOE's Low-Level Waste Management ES ampersand H vulnerabilities. Volume I. Final report

    International Nuclear Information System (INIS)

    1996-05-01

    The Department of Energy (DOE) conducted a comprehensive complex-wide review of its management of low-level waste (LLW) and the radioactive component of mixed low-level waste (MLLW). This review was conducted in response to a recommendation from the Defense Nuclear Facilities Safety Board (DNFSB) which was established and authorized by Congress to oversee DOE. The DNFSB's recommendation concerning conformance with safety standards at DOE LLW sites was issued on September 8, 1994 and is referred to as Recommendation 94-2. DOE's Implementation Plan for its response to Recommendation 94-2 was submitted to the DNFSB on March 31, 1995. The DNFSB recommended that a complex-wide review of DOE's LLW management be initiated. The goal of the complex-wide review of DOE's LLW management system was to identify both programmatic and physical vulnerabilities that could lead to unnecessary radiation exposure of workers or the public or unnecessary releases of radioactive materials to the environment. Additionally, the DNFSB stated that an objective of the complex-wide review should be to establish the dimensions of the DOE LLW problem and support the identification of corrective actions to address safe disposition of past, present, and future volumes of LLW. The complex-wide review involved an evaluation of LLW management activities at 38 DOE facilities at 36 sites that actively manage LLW and MLLW

  19. Cell volume regulation: physiology and pathophysiology

    DEFF Research Database (Denmark)

    Lambert, I H; Hoffmann, E K; Pedersen, Stine Helene Falsig

    2008-01-01

    are sensed are still far from clear, significant progress has been made with respect to the nature of the sensors, transducers and effectors that convert a change in cell volume into a physiological response. In the present review, we summarize recent major developments in the field, and emphasize......Cell volume perturbation initiates a wide array of intracellular signalling cascades, leading to protective and adaptive events and, in most cases, activation of volume-regulatory osmolyte transport, water loss, and hence restoration of cell volume and cellular function. Cell volume is challenged....../hypernatremia. On the other hand, it has recently become clear that an increase or reduction in cell volume can also serve as a specific signal in the regulation of physiological processes such as transepithelial transport, cell migration, proliferation and death. Although the mechanisms by which cell volume perturbations...

  20. Delphi-RAND consensus of the Spanish Society of Internal Medicine on the controversies in anticoagulant therapy and prophylaxis in medical diseases. INTROMBIN Project (Uncertainty in thromboprophylaxis in internal medicine).

    Science.gov (United States)

    Ruiz-Ruiz, F; Medrano, F J; Navarro-Puerto, M A; Rodríguez-Torres, P; Romero-Alonso, A; Santos-Lozano, J M; Alonso-Ortiz Del Rio, C; Varela-Aguilar, J M; Calderón, E J; Marín-León, I

    2018-05-21

    The aim of this study was to determine the opinion of internists on the management of anticoagulation and thromboembolism prophylaxis in complex clinical scenarios in which the risk-benefit ratio of surgery is narrow and to develop a consensus document on the use of drugs anticoagulant therapy in this patient group. To this end, we identified by consensus the clinical areas of greatest uncertainty, a survey was created with 20 scenarios laid out in 40 clinical questions, and we reviewed the specific literature. The survey was distributed among the internists of the Spanish Society of Internal Medicine (SEMI) and was completed by 290 of its members. The consensus process was implemented by changing the Delphi-RAND appropriateness method in an anonymous, double-round process that enabled an expert panel to identify the areas of agreement and uncertainty. In our case, we also added the survey results to the panel, a methodological innovation that helps provide additional information on the standard clinical practice. The result of the process is a set of 19 recommendations formulated by SEMI experts, which helps establish guidelines for action on anticoagulant therapy in complex scenarios (high risk or active haemorrhage, short life expectancy, coexistence of antiplatelet therapy or comorbidities such as kidney disease and liver disease), which are not uncommon in standard clinical practice. Copyright © 2018 Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI). All rights reserved.

  1. World-volumes and string target spaces

    International Nuclear Information System (INIS)

    Green, M.B.

    1996-01-01

    String duality suggests a fascinating juxtoposition of world-volume and target-space dynamics. This is particularly apparent in the D-brane description of stringy solitons that forms a major focus of this article (which is not intended to be a comprehensive review of this extensive and sophisticated subject). The article is divided into four sections: the oligarchy of string world-sheets; p-branes and world-volumes; world-sheets for world-volumes; boundary states. D-branes and space-time supersymmetry (orig.)

  2. Ultrasound automated volume calculation in reproduction and in pregnancy.

    Science.gov (United States)

    Ata, Baris; Tulandi, Togas

    2011-06-01

    To review studies assessing the application of ultrasound automated volume calculation in reproductive medicine. We performed a literature search using the keywords "SonoAVC, sonography-based automated volume calculation, automated ultrasound, 3D ultrasound, antral follicle, follicle volume, follicle monitoring, follicle tracking, in vitro fertilization, controlled ovarian hyperstimulation, embryo volume, embryonic volume, gestational sac, and fetal volume" and conducted the search in PubMed, Medline, EMBASE, and the Cochrane Database of Systematic Reviews. Reference lists of identified reports were manually searched for other relevant publications. Automated volume measurements are in very good agreement with actual volumes of the assessed structures or with other validated measurement methods. The technique seems to provide reliable and highly reproducible results under a variety of conditions. Automated measurements take less time than manual measurements. Ultrasound automated volume calculation is a promising new technology which is already used in daily practice especially for assisted reproduction. Improvements to the technology will undoubtedly render it more effective and increase its use. Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  3. Air & Space Power Journal. Volume 26, Number 5. September-October 2012

    Science.gov (United States)

    2012-10-01

    of their air support through variations in doctrine or expansion of available options to meet the mission requirements. Envisioning mul­...Alfred Goldberg and Lt Col Donald Smith, Army–Air Force Relations: The Close Air Support Issue, R-906-PR (Santa Monica, CA: RAND, October 1971), 16...most impor­ tant near term priority” and recognizing it as “the most effective way to generate capacity, increase tempo , [and achieve] maximum

  4. LLE Review Quarterly Report (January-March 2002). Volume 90

    Energy Technology Data Exchange (ETDEWEB)

    Donaldson, William R. [Univ. of Rochester, NY (United States). Lab. for Laser Energetics

    2002-03-01

    This volume of the LLE Review, covering January-March 2002, features “First Results from Cryogenic Target Implosions on OMEGA” by C. Stoeckl et al. (p. 49). This article describes initial results from direct-drive spherical cryogenic target implosions on the 60-beam OMEGA laser system. These experiments are part of the scientific base leading to direct-drive ignition implosions planned for the National Ignition Facility (NIF). Results shown include neutron yield, secondary-neutron and proton yields, the time of peak neutron emission, and both time-integrated and time-resolved x-ray images of the imploding core. The experimental values are compared with 1-D numerical simulations. The target with an ice-layer nonuniformity of srms = 9 mm showed 30% of the 1-D predicted neutron yield. These initial results are encouraging for future cryogenic implosions on OMEGA and the NIF. Other articles in this issue are titled the following: Equation-of-State Measurements of Porous Materials on OMEGA: Numerical Modeling; Observations of Modulated Shock Waves in Solid Targets Driven by Spatially Modulated Laser Beams; Time-Dependent Electron Thermal Flux Inhibition in direct-Drive Laser Implosions; Precision Spectral Sculpting of Broadband FM Pulses Amplified in a Narrowband Medium; Electric-Field-Induced Motion of Polymer Cholesteric Liquid Crystal Flakes in a Moderately Conductive Fluid; and, Femtosecond Response of a Freestanding LT-GaAs Photoconductive Switch.

  5. Understanding Mathematics-A Review

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 6; Issue 5. Understanding Mathematics – A Review. Shashidhar Jagadeeshan. Book Review Volume 6 Issue 5 May ... Author Affiliations. Shashidhar Jagadeeshan1. Centre for Learning, 469, 9th Cross, 1st Block, Jayanagar, Bangalore 560 011, India.

  6. Licensing an assured isolation facility for low-level radioactive waste. Volume 2: Recommendations on the content and review of an application

    International Nuclear Information System (INIS)

    Silverman, D.J.; Bauser, M.A.; Baird, R.D.

    1998-07-01

    This report provides a detailed set of proposed criteria and guidance for the preparation of a license application for an assured isolation facility (AIF). The report is intended to provide a detailed planning basis upon which a prospective applicant may begin pre-licensing discussions with the Nuclear Regulatory Commission and initiate development of a license application. The report may also be useful to the NRC or to state regulatory agencies that may be asked to review such an application. Volume 1 of this report provides background information, and describes the licensing approach and methodology. Volume 2 identifies specific information that is recommended for inclusion in a license application

  7. Licensing an assured isolation facility for low-level radioactive waste. Volume 2: Recommendations on the content and review of an application

    Energy Technology Data Exchange (ETDEWEB)

    Silverman, D.J.; Bauser, M.A. [Morgan, Lewis and Bockius, Washington, DC (United States); Baird, R.D. [Rogers and Associates Engineering Corp., Salt Lake City, UT (United States)

    1998-07-01

    This report provides a detailed set of proposed criteria and guidance for the preparation of a license application for an assured isolation facility (AIF). The report is intended to provide a detailed planning basis upon which a prospective applicant may begin pre-licensing discussions with the Nuclear Regulatory Commission and initiate development of a license application. The report may also be useful to the NRC or to state regulatory agencies that may be asked to review such an application. Volume 1 of this report provides background information, and describes the licensing approach and methodology. Volume 2 identifies specific information that is recommended for inclusion in a license application.

  8. Review article: volume expansion in patients with cirrhosis

    DEFF Research Database (Denmark)

    Henriksen, Jens Henrik; Kiszka-Kanowitz, Marianne; Bendtsen, Flemming

    2002-01-01

    Adequate size and distribution of the circulating medium are important for cardiovascular function, tissue oxygenation, and fluid homoeostasis. Patients with cirrhosis have cardiovascular dysfunction with a hyperkinetic systemic circulation, abnormal distribution of the blood volume, vasodilation...

  9. Color vision deficiency compensation for Visual Processing Disorder using Hardy-Rand-Rittler test and color transformation

    Science.gov (United States)

    Balbin, Jessie R.; Pinugu, Jasmine Nadja J.; Bautista, Joshua Ian C.; Nebres, Pauline D.; Rey Hipolito, Cipriano M.; Santella, Jose Anthony A.

    2017-06-01

    Visual processing skill is used to gather visual information from environment however, there are cases that Visual Processing Disorder (VPD) occurs. The so called visual figure-ground discrimination is a type of VPD where color is one of the factors that contributes on this type. In line with this, color plays a vital role in everyday living, but individuals that have limited and inaccurate color perception suffers from Color Vision Deficiency (CVD) and still not aware on their case. To resolve this case, this study focuses on the design of KULAY, a Head-Mounted Display (HMD) device that can assess whether a user has a CVD or not thru the standard Hardy-Rand-Rittler (HRR) test. This test uses pattern recognition in order to evaluate the user. In addition, color vision deficiency simulation and color correction thru color transformation is also a concern of this research. This will enable people with normal color vision to know how color vision deficient perceives and vice-versa. For the accuracy of the simulated HRR assessment, its results were validated thru an actual assessment done by a doctor. Moreover, for the preciseness of color transformation, Structural Similarity Index Method (SSIM) was used to compare the simulated CVD images and the color corrected images to other reference sources. The output of the simulated HRR assessment and color transformation shows very promising results indicating effectiveness and efficiency of the study. Thus, due to its form factor and portability, this device is beneficial in the field of medicine and technology.

  10. Compilation of reports of the Advisory Committee on Reactor Safeguards, 1957-1984. Volume 2. Project Reviews G-P

    International Nuclear Information System (INIS)

    1985-04-01

    This six-volume compilation contains over 1000 reports prepared by the Advisory Committee on Reactor Safeguards from September 1957 through December 1984. The reports are divided into two groups: Part 1: ACRS Reports on Project Reviews, and Part 2: ACRS Reports on Generic Subjects. Part 1 contains ACRS reports alphabetized by project name and within project name by chronological order. Part 2 categorizes the reports by the most appropriate generic subject area and within subject area by chronological order

  11. LLE Review: Quarterly report, July--September 1994. Volume 60

    Energy Technology Data Exchange (ETDEWEB)

    Knauer, J.P. [ed.

    1994-12-31

    This volume contains articles on efficient generation of second-harmonic radiation from short-pulse lasers; calculation of the stabilization cutoff wave numbers for the Rayleigh-Taylor instability; a high-frequency silicon optical modulator; the angular dependence of stimulated Brillouin scattering; and femtosecond dynamics of ladder polymers. Three of these articles--second-harmonic generation, Rayleigh-Taylor cutoff wave numbers, and angular dependence of Brillouin scattering--are directly related to the OMEGA Upgrade, currently under construction. A summary of the status of the OMEGA Upgrade laser facility and the NLUF News for FY94 are included in this volume.

  12. Baixa prevalência de discromatopsia, pela 4ª edição do teste pseudoisocromático HRR (Hardy, Rand e Rittler), da população indígena de etnia terena da aldeia lalima na região de Miranda: Mato Grosso do Sul Low prevalence of dyschromatopsia using the fourth edition of HRR (Hardy, Rand and Rittler) pseudoisochromatic plate test among the Indian population of Lalima village, Terena

    OpenAIRE

    Marcos Rogério Mistro Piccinin; Juliana Ferrari Cunha; Herbert Paulo de Almeida; Cleiton Cassio Bach; Andréa Cristina Grubits Gonçalves de Oliveira Dossa; Reinaldo Ferreira da Silva; Valdir Filgueiras Pessoa

    2007-01-01

    OBJETIVO: Avaliar a freqüência de discromatopsias através da 4ª edição do teste pseudoisocromático HRR (Hardy, Rand and Rittler) entre a população indígena masculina da aldeia Lalima, etnia Terena, na região de Miranda-MS. MÉTODOS: Foram realizadas viagens à aldeia Lalima em Miranda-MS, nos meses de janeiro e fevereiro de 2005. As viagens para realizar os exames só foram iniciadas após o projeto ter sido avaliado e aprovado pelos Comitê de Ética e Pesquisa da UFMS, Comitê Nacional de Ética e ...

  13. October 2015 Phoenix pulmonary journal club: lung volume reduction

    Directory of Open Access Journals (Sweden)

    Mathew M

    2015-11-01

    Full Text Available No abstract available. Article truncated at 150 words. The October 2015 pulmonary journal club focused on the review of older studies evaluating lung volume reduction surgery and how this has transitioned toward the development of non-surgical modes of lung volume reduction. The physiology behind dyspnea in chronic obstructive pulmonary disease (COPD is a complex process. One of the proposed mechanisms has been hyperinflation associated with air trapping. In the mid 1990s studies by Cooper and Peterson (1 offered a promising approach in which lung volume reduction (LVR could improve ventilatory mechanics and improve dyspnea. As the procedure gained more popularity, additional larger scale trials were performed to support its validity. We reviewed 2 studies looking at lung volume reduction. The first was "The Effect of Lung Volume Reduction Surgery In Patients With Severe Emphysema” (2 . This was a smaller, randomized controlled trial (RCT that looked at 2 groups of 24 patients. Once group received LVR while the ...

  14. Medical review practices for driver licensing volume 2: case studies of medical referrals and licensing outcomes in Maine, Ohio, Oregon, Texas, Washington, and Wisconsin.

    Science.gov (United States)

    2017-03-01

    This is the second of three reports examining driver medical review practices in the United States and how : they fulfill the basic functions of identifying, assessing, and rendering licensing decisions on medically at-risk : drivers. This volume pre...

  15. Moderate and Radical Islam

    National Research Council Canada - National Science Library

    Rabasa, Angel

    2005-01-01

    This report presents the statement of Angel Rabasa, PhD, Senior Policy Analyst, The RAND Corporation, to the Committee on Armed Services, Defense Review Terrorism and Radical Islam Gap Panel, United...

  16. Physiology of cell volume regulation in vertebrates

    DEFF Research Database (Denmark)

    Hoffmann, Else K; Lambert, Ian H; Pedersen, Stine F

    2009-01-01

    and their regulation by, e.g., membrane deformation, ionic strength, Ca(2+), protein kinases and phosphatases, cytoskeletal elements, GTP binding proteins, lipid mediators, and reactive oxygen species, upon changes in cell volume. We also discuss the nature of the upstream elements in volume sensing in vertebrate...... organisms. Importantly, cell volume impacts on a wide array of physiological processes, including transepithelial transport; cell migration, proliferation, and death; and changes in cell volume function as specific signals regulating these processes. A discussion of this issue concludes the review.......The ability to control cell volume is pivotal for cell function. Cell volume perturbation elicits a wide array of signaling events, leading to protective (e.g., cytoskeletal rearrangement) and adaptive (e.g., altered expression of osmolyte transporters and heat shock proteins) measures and, in most...

  17. Finite Volumes for Complex Applications VII

    CERN Document Server

    Ohlberger, Mario; Rohde, Christian

    2014-01-01

    The methods considered in the 7th conference on "Finite Volumes for Complex Applications" (Berlin, June 2014) have properties which offer distinct advantages for a number of applications. The second volume of the proceedings covers reviewed contributions reporting successful applications in the fields of fluid dynamics, magnetohydrodynamics, structural analysis, nuclear physics, semiconductor theory and other topics. The finite volume method in its various forms is a space discretization technique for partial differential equations based on the fundamental physical principle of conservation. Recent decades have brought significant success in the theoretical understanding of the method. Many finite volume methods preserve further qualitative or asymptotic properties, including maximum principles, dissipativity, monotone decay of free energy, and asymptotic stability. Due to these properties, finite volume methods belong to the wider class of compatible discretization methods, which preserve qualitative propert...

  18. LLE Review Quarterly Report October - December 2011. Volume 129

    Energy Technology Data Exchange (ETDEWEB)

    Shvydky, Alex [Univ. of Rochester, NY (United States). Lab. for Laser Energetics

    2011-12-01

    This volume of LLE Review, covering October–December 2011, features “Crossed-Beam Energy Transfer in Direct-Drive Implosions” by I. V. Igumenshchev, W. Seka, D. H. Edgell, D. T. Michel, D. H. Froula, R. S. Craxton, R. Follett, J. H. Kelly, T. Z. Kosc, J. F. Myatt, T. C. Sangster, A. Shvydky, S. Skupsky, and C. Stoeckl (LLE); V. N. Goncharov and A. V. Maximov (LLE and Department of Mechanical Engineering, U. of Rochester); L. Divol and P. Michel (LLNL); and R. L. McCrory and D. D. Meyerhofer (LLE and Departments of Mechanical Engineering and Physics, U. of Rochester). In this article (p. 1), direct-drive–implosion experiments on the OMEGA laser [T. R. Boehly et al., Opt. Commun. 133, 495 (1995)] have shown discrepancies between simulations of the scattered (non-absorbed) light levels and measured ones that indicates the presence of a mechanism that reduces laser coupling efficiency by 10% to 20%. The authors attribute this degradation in laser coupling to crossed-beam energy transfer (CBET)— which is electromagnetically seeded—low-gain stimulated Brillouin scattering. CBET scatters energy from the central portion of the incoming light beam to outgoing light, reducing the laser absorption and hydrodynamic efficiency of implosions. One-dimensional hydrodynamic simulations including CBET show good agreement with all observables in implosion experiments on OMEGA. Three strategies to mitigate CBET and improve laser coupling are considered: the use of narrow beams, multicolor lasers, and higher-Z ablators. Experiments on OMEGA using narrow beams have demonstrated improvements in implosion performance.

  19. AJER VOLUME II-JULY 2014

    African Journals Online (AJOL)

    user

    African Journal of Economic Review, Volume 1I, Issue 2, July 2014 ..... This paper also carries out the Chow-break point test (stability test) to test .... Unlike other East African countries, Rwanda has had a lot of political instabilities characterized.

  20. Appropriate customization of radiation therapy for stage II and III rectal cancer: Executive summary of an ASTRO Clinical Practice Statement using the RAND/UCLA Appropriateness Method.

    Science.gov (United States)

    Goodman, Karyn A; Patton, Caroline E; Fisher, George A; Hoffe, Sarah E; Haddock, Michael G; Parikh, Parag J; Kim, John; Baxter, Nancy N; Czito, Brian G; Hong, Theodore S; Herman, Joseph M; Crane, Christopher H; Hoffman, Karen E

    2016-01-01

    To summarize results of a Clinical Practice Statement on radiation therapy for stage II-III rectal cancer, which addressed appropriate customization of (neo)adjuvant radiation therapy and use of non-surgical therapy for patients who are inoperable or refuse abdominoperineal resection. The RAND/University of California, Los Angeles, Appropriateness Method was applied to combine current evidence with multidisciplinary expert opinion. A systematic literature review was conducted and used by the expert panel to rate appropriateness of radiation therapy options for different clinical scenarios. Treatments were categorized by median rating as Appropriate, May Be Appropriate, or Rarely Appropriate. In the neoadjuvant setting, chemoradiation was rated Appropriate and the ratings indicated short-course radiation therapy, chemotherapy alone, and no neoadjuvant therapy are potential options in selected patients. However, neoadjuvant endorectal brachytherapy was rated Rarely Appropriate. For adjuvant therapy, chemoradiation (plus ≥4 months of chemotherapy) was rated Appropriate and chemotherapy alone May Be Appropriate for most scenarios. For medically inoperable patients, definitive external beam radiation therapy and chemotherapy alone were rated May Be Appropriate, whereas endorectal brachytherapy and chemoradiation plus endorectal brachytherapy were possible approaches for some scenarios. The last option, definitive chemoradiation, was rated Appropriate to May Be Appropriate based on performance status. Finally, for patients with low-lying tumors refusing abdominoperineal resection, definitive chemoradiation alone, chemoradiation plus endorectal brachytherapy, and chemoradiation plus external beam radiation therapy were all rated Appropriate. This Clinical Practice Statement demonstrated the central role of radiation therapy in stage II-III rectal cancer management and evaluated ways to better individualize its use in the neoadjuvant, adjuvant, and definitive settings

  1. Software Engineering and Knowledge Engineering Theory and Practice Volume 2

    CERN Document Server

    2012-01-01

    The volume includes a set of selected papers extended and revised from the I2009 Pacific-Asia Conference on Knowledge Engineering and Software Engineering (KESE 2009) was held on December 19~ 20, 2009, Shenzhen, China.   Volume 2 is to provide a forum for researchers, educators, engineers, and government officials involved in the general areas of Knowledge Engineering and Communication Technology to disseminate their latest research results and exchange views on the future research directions of these fields. 135 high-quality papers are included in the volume. Each paper has been peer-reviewed by at least 2 program committee members and selected by the volume editor Prof.Yanwen Wu.   On behalf of the this volume, we would like to express our sincere appreciation to all of authors and referees for their efforts reviewing the papers. Hoping you can find lots of profound research ideas and results on the related fields of Knowledge Engineering and Communication Technology. 

  2. Quadrennial Review of Military Compensation (6th). Executive Summary. Volumes 1 thru 1C, and Volumes 2 thru 3

    Science.gov (United States)

    1988-08-01

    CIVILIAN EARNINGS PROFILE: ENLISTED SOURCE: SYLLOGISTICS 2-24 6th ORNC Esport -Volum 11 participation and higher than that of civilian counterparts in...7-26 6th QRNC esport - Volume I m Eliminate the existing 80 percent limiltation onmeai/entertairment deductions incurred in connection with the

  3. Natural look in volume restoration.

    Science.gov (United States)

    Lupo, Mary P

    2008-09-01

    Filling and volumizing injection procedures are currently widely used for facial augmentation and re-establishing a youthful appearance. Aesthetic physicians have advanced from the practice of treating single lines and wrinkles towards filling large facial areas to globally restore natural facial contours and meet patient demand for nonsurgical rejuvenation. This review describes the different categories of fillers and volumizers based on their duration of action and ability to create a natural looking effect; they can be broadly classified as temporary or long-lasting biodegradable agents, or permanent nonbiodegradable agents. Temporary fillers are effective to correct lines and wrinkles, but may not adequately meet the need for global facial rejuvenation and volume replacement in a long-term, cost-efficient manner. Permanent fillers for global restoration pose the issue of long-term safety, and may not be compatible with changes in facial architecture with continued aging. Longer lasting volumizers provide patients with a durable, effective option for the restoration of facial volume and the re-establishment of youthful facial contours. Temporary fillers and volumizers may also be used in combination to provide a wide source of options for the global restoration and rejuvenation of the face.

  4. Estimating traffic volume on Wyoming low volume roads using linear and logistic regression methods

    Directory of Open Access Journals (Sweden)

    Dick Apronti

    2016-12-01

    Full Text Available Traffic volume is an important parameter in most transportation planning applications. Low volume roads make up about 69% of road miles in the United States. Estimating traffic on the low volume roads is a cost-effective alternative to taking traffic counts. This is because traditional traffic counts are expensive and impractical for low priority roads. The purpose of this paper is to present the development of two alternative means of cost-effectively estimating traffic volumes for low volume roads in Wyoming and to make recommendations for their implementation. The study methodology involves reviewing existing studies, identifying data sources, and carrying out the model development. The utility of the models developed were then verified by comparing actual traffic volumes to those predicted by the model. The study resulted in two regression models that are inexpensive and easy to implement. The first regression model was a linear regression model that utilized pavement type, access to highways, predominant land use types, and population to estimate traffic volume. In verifying the model, an R2 value of 0.64 and a root mean square error of 73.4% were obtained. The second model was a logistic regression model that identified the level of traffic on roads using five thresholds or levels. The logistic regression model was verified by estimating traffic volume thresholds and determining the percentage of roads that were accurately classified as belonging to the given thresholds. For the five thresholds, the percentage of roads classified correctly ranged from 79% to 88%. In conclusion, the verification of the models indicated both model types to be useful for accurate and cost-effective estimation of traffic volumes for low volume Wyoming roads. The models developed were recommended for use in traffic volume estimations for low volume roads in pavement management and environmental impact assessment studies.

  5. Proceedings of the seventh annual gasification and gas stream cleanup systems contractors review meeting: Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Ghate, M.R.; Markel, K.E. Jr.; Jarr, L.A.; Bossart, S.J. (eds.)

    1987-08-01

    On June 16 through 19, 1987, METC sponsored the Seventh Annual Gasification and Gas Stream Cleanup Systems Contractors Review Meeting which was held at the Sheraton Lakeview Conference Center in Morgantown, West Virginia. The primary purpose of the meeting was threefold: to review the technical progress and current status of the gasification and gas stream cleanup projects sponsored by the Department of Energy; to foster technology exchange among participating researchers and other technical communities; to facilitate interactive dialogues which would identify research needs that would make coal-based gasification systems more attractive economically and environmentally. More than 310 representatives of Government, academia, industry, and foreign energy research organizations attended the 4-day meeting. Fifty-three papers and thirty poster displays were presented summarizing recent developments in the gasification and gas stream cleanup programs. Volume I covers information presented at sessions 1 through 4 on systems for the production of Co-products and industrial fuel gas, environmental projects, and components and materials. Individual papers have been processed for the Energy Data Base.

  6. Proceedings of the seventh annual gasification and gas stream cleanup systems contractors review meeting: Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    Ghate, M.R.; Markel, K.E. Jr.; Jarr, L.A.; Bossart, S.J. (eds.)

    1987-08-01

    On June 16 through 19, 1987, METC sponsored the Seventh Annual Gasification and Gas Stream Cleanup Systems Contractors Review Meeting which was held at the Sheraton Lakeview Conference Center in Morgantown, West Virginia. The primary purpose of the meeting was threefold: to review the technical progress and current status of the gasification and gas stream cleanup projects sponsored by the Department of Energy; to foster technology exchange among participating researchers and other technical communities; to facilitate interactive dialogues which would identify research needs that would make coal-based gasification systems more attractive economically and environmentally. More than 310 representatives of Government, academia, industry, and foreign energy research organizations attended the 4-day meeting. Fifty-three papers and thirty poster dsplays were presented summarizing recent developments in the gasification and gas stream cleanup programs. Volume II covers papers presented at sessions 5 and 6 on system for the production of synthesis gas, and on system for the production of power. All papers have been processed for inclusion in the Energy Data Base.

  7. Total energy cycle assessment of electric and conventional vehicles: an energy and environmental analysis. Volume 4: peer review comments on technical report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-01-01

    This report compares the energy use, oil use and emissions of electric vehicles (EVs) with those of conventional, gasoline-powered vehicles (CVs) over the total life cycle of the vehicles. The various stages included in the vehicles` life cycles include vehicle manufacture, fuel production, and vehicle operation. Disposal is not included. An inventory of the air emissions associated with each stage of the life cycle is estimated. Water pollutants and solid wastes are reported for individual processes, but no comprehensive inventory is developed. Volume IV includes copies of all the external peer review comments on the report distributed for review in July 1997.

  8. Experimental model for low level laser therapy on ischemic random skin flap in rats Modelo experimental para laserterapia de baixa intensidade em retalho cutâneo randômico isquêmico em ratos

    Directory of Open Access Journals (Sweden)

    Rodrigo Paschoal Prado

    2006-08-01

    Full Text Available PURPOSE: To develop an experimental model to be used in the study of low level Laser therapy on viability of random skin flap in rats. METHODS: The sample was 24 Wistar-EPM rats. The random skin flap measured 10 x 4 cm and a plastic sheet was interposed between the flap and donor site. Group 1 (control underwent sham irradiation with diode laser (830 nm. Group 2 was submitted to laser irradiation with diode laser (830 nm. The animals were submitted to Laser therapy with 36 J/cm² energy density (72 seconds immediately after the surgery and on the four subsequent days. The probe was usually held in contact with the skin flap surface on a point at 2.5 cm cranial from the flap base. On the seventh postoperative day, the percentage of necrotic area was measured and calculated. RESULTS: Group 1 reached an average necrotic area of 48.86%, Group 2 - 23.14%. After the statistic analysis, compared with the control group, Group 2 showed a statistically significant increase in survival area (pOBJETIVO: Propor o desenvolvimento de um modelo experimental para verificar o efeito da laserterapia de baixa intensidade na viabilidade do retalho cutâneo randômico em ratos. MÉTODOS: A amostra constituiu-se de 24 ratos, da linhagem Wistar-EPM. O retalho cutâneo randômico foi realizado com dimensões de 10x4 cm e uma barreira plástica foi interposta entre o mesmo e o leito doador. O Grupo 1 (controle, foi submetido a uma simulação de tratamento com a irradiação laser de diodo (830 nm. O Grupo 2 foi submetido à irradiação laser de diodo (830 nm. Os animais foram submetidos a terapia a laser com densidade de energia de 36 J/cm2 (72 segundos imediatamente após a operação e nos outros quatros dias subseqüentes. A caneta do laser foi posicionada a 90 graus em contato com o retalho cutâneo em um ponto a 2,5 cm da base cranial do retalho. No sétimo dia pós-operatório foram calculadas as porcentagens da área de necrose. RESULTADOS: O Grupo 1 apresentou

  9. Book Reviews

    OpenAIRE

    Joann Kovacich

    2013-01-01

    Annual Review of Gerontology and Geriatrics 2010-2013 Volume 30, 2010: Focus on Biobehavioral Perspectives on Health in Late Life (Keith E. Whitfield, ed.) Linda J. Keilman , Michigan State University Volume 31, 2011: Pathways Through the Transitions of Care for Older Adults. (Peggye Dilworth-Anderson and Mary H. Palmer, eds.) Rachel Sona Reed, The Pasadena Village Volume 32, 2012: Emerging Perspectives on Resilience in Adulthood and Later Life (Bert Hayslip Jr., Gregory S...

  10. Naval Law Review, Volume 51, 2005

    National Research Council Canada - National Science Library

    Romero, Joseph; Belliss, Richard D; Tideswell, Tammy P; Antolin-Jenkins, Vida M; O'Neil, Kevin R; Wildhack, III, William A; McLaughlin, Rob; Gonzalez, Jason A; Sarnoski, Stephen R

    2005-01-01

    .... This issue of "Naval Law Review" contains the following articles: "Of War and Punishment: 'Time of War' In Military Jurisprudence and a Call for Congress to Define Its Meaning," by LCDR Joseph Romero, JAGC, USN...

  11. Naval Law Review. Volume 58

    Science.gov (United States)

    2009-01-01

    www.docstoc.com/docs/445063/when-is-a-cyberconflict-an-armed-conflict). 5 See discussion infra part II.B. 6 See D. Jean Veta & Rochelle E . Rubin...Kisor NO PORT IN A STORM – A REVIEW OF RECENT HISTORY AND LEGAL CONCEPTS RESULTING IN THE EXTINCTION OF PORTS OF REFUGE 65 Lieutenant Lena E ...goods purchased prior to the outbreak of hostilities was swept away in wartime. As “[ e ]very individual of the one nation must acknowledge every

  12. Evidence for Policy Making: Clinical Appropriateness Study of Lumbar Spine MRI Prescriptions Using RAND Appropriateness Method

    Directory of Open Access Journals (Sweden)

    Hossein Yousefi Manesh

    2013-01-01

    Full Text Available MRI is a new and expensive diagnostic technology, which has been used increasingly all over the world. Low back pain is a worldwide prevalent disorder and MRI technique is one of the several ways to diagnose it. This paper aims to identify the appropriateness of lumbar spine MRI prescriptions in Shiraz teaching hospitals using standardized RAND Appropriateness Method (RAM criteria. Methods This study consisted of two phases. The first phase involved a qualitative enquiry and the second phase had a quantitative cross-sectional nature. In the first phase RAM was used for developing lumbar spine MRI indications and scenarios. In the second phase, the finalized scenarios were compared with the history and physical examination of 300 patients with low back pain. The rate of appropriateness of lumbar spine MRI prescription was then calculated. Results Of 300 cases of lumbar spine MRI prescriptions, approximately 167 (56% were considered inappropriate, 72 (24% were uncertain, and 61 (20% were deemed to be appropriate. The economic burden of inappropriate prescriptions was calculated at 88,009,000 Rials. In addition, the types of expertise and physical examination were considered as related factors to appropriateness of prescriptions. Conclusion In conclusion, a large proportion of lumbar spine MRI prescriptions, which result in financial burden on the insurance companies and the patients alike is unnecessary. This study suggests that policy makers consider this evidence while decision-making. Our findings highlight the imperative role of Health Technology Assessment (HTA and Clinical Practice Guidelines (CPGs. As a result, developing local clinical guidelines may create the commitment needed in physicians in prescribing appropriate prescriptions within the health sector. The study further recommends that appropriate scenarios should be considered as a criterion for payment and reimbursement.

  13. Provider volume and outcomes for oncological procedures.

    LENUS (Irish Health Repository)

    Killeen, S D

    2012-02-03

    BACKGROUND: Oncological procedures may have better outcomes if performed by high-volume providers. METHODS: A review of the English language literature incorporating searches of the Medline, Embase and Cochrane collaboration databases was performed. Studies were included if they involved a patient cohort from 1984 onwards, were community or population based, and assessed health outcome as a dependent variable and volume as an independent variable. The studies were also scored quantifiably to assess generalizability with respect to any observed volume-outcome relationship and analysed according to organ system; numbers needed to treat were estimated where possible. RESULTS: Sixty-eight relevant studies were identified and a total of 41 were included, of which 13 were based on clinical data. All showed either an inverse relationship, of variable magnitude, between provider volume and mortality, or no volume-outcome effect. All but two clinical reports revealed a statistically significant positive relationship between volume and outcome; none demonstrated the opposite. CONCLUSION: High-volume providers have a significantly better outcome for complex cancer surgery, specifically for pancreatectomy, oesphagectomy, gastrectomy and rectal resection.

  14. Health related quality of life measures in Arabic speaking populations: a systematic review on cross-cultural adaptation and measurement properties.

    Science.gov (United States)

    Al Sayah, Fatima; Ishaque, Sana; Lau, Darren; Johnson, Jeffrey A

    2013-02-01

    This systematic review was conducted to identify generic health related quality of life (HRQL) measures translated into Arabic, and evaluate their cross-cultural adaptation and measurement properties. Six databases were searched, relevant journals were hand searched, and reference lists of included studies were reviewed. Previously established criteria were used to evaluate the cross-cultural adaptation of the identified instruments and their measurement properties. Twenty studies that reported the Arabic translations and adaptations of HRQL measures and/or their measurement properties were included in this review. The identified instruments were SF-36, RAND-36, WHOQOL-Bref, COOP/WONCA charts, EQ-5D, and QLI. Cross-cultural adaptations of all measures were of moderate to good quality, and evaluation of measurement properties was limited due to insufficiency of evidence. Based on cross-cultural adaptation evaluation, each instrument is more applicable to the population for whom it was adapted, and to other Arabic populations of similar culture and language specific idioms. This review facilitates the selection among existing Arabic versions of generic HRQL for use in particular Arabic countries. However, each of the translated versions requires further investigation of measurement properties before more concrete recommendations could be made.

  15. AJER VOLUME I-JULY 2013

    African Journals Online (AJOL)

    Dr Kazungu

    African Journal of Economic Review, Volume 1, Issue 2, July 2013 ... The government of Tanzania has been pursuing unprecedented reforms in local government ... Shapiro (2006) for Mexico, but negative results obtained by Di Gropello (2002) for .... All the variables except the growth rate of public expenditure to GDP.

  16. Report on the Survey of the Design Review of New Reactor Applications. Volume 3: Reactor

    International Nuclear Information System (INIS)

    Downey, Steven; Monninger, John; Nevalainen, Janne; Lorin, Aurelie; ); Webster, Philip; Joyer, Philippe; Kawamura, Tomonori; Lankin, Mikhail; Kubanyi, Jozef; Haluska, Ladislav; Persic, Andreja; Reierson, Craig; Kang, Kyungmin; Kim, Walter

    2016-01-01

    At the tenth meeting of the CNRA Working Group on the Regulation of New Reactors (WGRNR) in March 2013, the Working Group agreed to present the responses to the Second Phase, or Design Phase, of the Licensing Process Survey as a multi-volume text. As such, each report will focus on one of the eleven general technical categories covered in the survey. The general technical categories were selected to conform to the topics covered in the International Atomic Energy Agency (IAEA) Safety Guide GS-G-4.1. This document, which is the third report on the results of the Design Phase Survey, focuses on the Reactor. The Reactor category includes the following technical topics: fuel system design, reactor internals and core support, nuclear design and core nuclear performance, thermal and hydraulic design, reactor materials, and functional design of reactivity control system. For each technical topic, the member countries described the information provided by the applicant, the scope and level of detail of the technical review, the technical basis for granting regulatory authorisation, the skill sets required and the level of effort needed to perform the review. Based on a comparison of the information provided by the member countries in response to the survey, the following observations were made: - Although the description of the information provided by the applicant differs in scope and level of detail among the member countries that provided responses, there are similarities in the information that is required. - All of the technical topics covered in the survey are reviewed in some manner by all of the regulatory authorities that provided responses. - Design review strategies most commonly used to confirm that the regulatory requirements have been met include document review and independent verification of calculations, computer codes, or models used to describe the design and performance of the core and the fuel. - It is common to consider operating experience and

  17. 2015 Workplace and Gender Relations Survey of Reserve Component Members: Statistical Methodology Report

    Science.gov (United States)

    2016-03-17

    and sexual harassment in the U.S. military: Volume 2. Estimates for Department of Defense service members from the 2014 RAND military workplace ... Sexual harassment , gender discrimination, and sexual assault. The 2014 RMWS nonresponse adjustment involved two steps, each of which produced a...were necessary. Using completed 2015 cases, six outcome variables were modeled for females: sexual harassment , gender discrimination, sexual quid

  18. Topical report review status. Volume 7, No. 2

    International Nuclear Information System (INIS)

    1984-11-01

    Purpose of this document is to provide periodic progress reports of on-going topical report reviews, to identify those topical reports for which the NRC staff review has been completed and those which are under review and to provide NRC management with sufficient information regarding the conduct of the topical report program to permit taking whatever actions are deemed necessary or appropriate. This document is also intended to be a source of information to NRC Licensing Project Managers and other NRC personnel regarding the status of topical reports which may be referenced in applications for which they have responsibility

  19. Salvage Treatment for Recurrent Intracranial Germinoma After Reduced-Volume Radiotherapy: A Single-Institution Experience and Review of the Literature

    International Nuclear Information System (INIS)

    Hu, Yu-Wen; Huang, Pin-I; Wong, Tai-Tong; Ho, Donald Ming-Tak; Chang, Kai-Ping; Guo, Wan-Yuo; Chang, Feng-Chi; Shiau, Cheng-Yin; Liang, Muh-Lii; Lee, Yi-Yen

    2012-01-01

    Purpose: Intracranial germinomas (IGs) are highly curable with radiotherapy (RT). However, recurrence still occurs, especially when limited-field RT is applied, and the optimal salvage therapy remains controversial. Methods and Materials: Between January 1989 and December 2010, 14 patients with clinically or pathologically diagnosed recurrent IGs after RT were reviewed at our institution. Of these, 11 received focal-field RT, and the other 3 received whole-brain irradiation, whole-ventricle irradiation, and Gamma Knife radiosurgery as the respective first course of RT. In addition, we identified from the literature 88 patients with recurrent IGs after reduced-volume RT, in whom the details of salvage therapy were recorded. Results: The median time to recurrence was 30.3 months (range, 3.8–134.9 months). One patient did not receive further treatment and was lost during follow-up. Of the patients, 7 underwent salvage with craniospinal irradiation (CSI) plus chemotherapy (CT), 4 with CSI alone, 1 with whole-brain irradiation plus CT, and 1 with Gamma Knife radiosurgery. The median follow-up time was 105.1 months (range, 24.2–180.9 months). Three patients died without evidence of disease progression: two from second malignancies and one from unknown cause. The others remained disease free. The 3-year survival rate after recurrence was 83.3%. A total of 102 patients from our study and the literature review were analyzed to determine the factors affecting prognosis and outcomes. After recurrence, the 5-year survival rates were 71% and 92.9% for all patients and for those receiving salvage CSI, respectively. Univariate analysis showed that initial RT volume, initial RT dose, initial CT, and salvage RT type were significant prognostic predictors of survival. On multivariable analysis, salvage CSI was the most significant factor (p = 0.03). Conclusions: Protracted follow-up is recommended because late recurrence is not uncommon. CSI with or without CT is an effective

  20. Topical report review status. Volume 9, No. 1

    International Nuclear Information System (INIS)

    1995-02-01

    This report provides industry with procedures for submitting topical reports, guidance on how the US Nuclear Regulatory Commission (NRC) processes and responds to topical report submittals, and an accounting, with review schedules, of all topical reports currently accepted for review by the NRC. This report is published semiannually

  1. Exercise and Sport Sciences Reviews. Volume 4, 1976.

    Science.gov (United States)

    Keogh, Jack, Ed.; Hutton, Robert S., Ed.

    EXERCISE AND SPORT SCIENCES REVIEWS is a journal, published once per year, in which reviews of research concerning biological, biomechanical, behavioral, and kinesiological aspects of human movement and performance are published. This book contains the following articles: (1) Organizational Processes in Motor Control, by A. M. Gentile and J.…

  2. Volume of the adrenal and pituitary glands in depression

    DEFF Research Database (Denmark)

    Kessing, Lars Vedel; Willer, Inge Stoel; Knorr, Ulla

    2011-01-01

    Numerous studies have shown that the hypothalamic-pituitary-adrenal (HPA) axis is hyperactive in some depressed patients. It is unclear whether such hyperactivity results in changed volumes of the adrenal glands, pituitary gland and hypothalamus. We systematically reviewed all controlled studies...... on the adrenal or pituitary glands or hypothalamus volume in unipolar depressive disorder published in PubMed 1966 to December 2009. We identified three studies that investigated the volume of the adrenal glands and eight studies that examined the volume of the pituitary gland, but no studies on hypothalamus...... were found. Two out of three studies found a statistically significant increase in adrenal volume in patients compared to controls. Four out of eight studies found a statistically significant increase in pituitary volume in patients compared to controls. Different methodological problems were...

  3. An Independent Scientific Assessment of Well Stimulation in California Volume II

    Energy Technology Data Exchange (ETDEWEB)

    Long, Jane C.S. [California Council on Science and Technology, Sacramento, CA (United States); Feinstein, Laura C. [California Council on Science and Technology, Sacramento, CA (United States); Bachmann, Corinne E. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Birkholzer, Jens T. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Camarillo, Mary Kay [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Domen, Jeremy K. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Foxall, William [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Houseworth, James [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Jin, Ling [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Jordan, Preston D. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Maddalena, Randy L. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); McKone, Thomas E. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Millstein, Dev E. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Reagan, Matthew T. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Sandelin, Whitney L. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Stringfellow, William T. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Varadharajan, Charuleka [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Cooley, Heather [Pacific Inst., Oakland, CA (United States); Donnelly, Kristina [Pacific Inst., Oakland, CA (United States); Heberger, Matthew G. [Pacific Inst., Oakland, CA (United States); Hays, Jake [PSE Healthy Energy, Berkeley, CA (United States); Shonkoff, Seth B.C. [PSE Healthy Energy, Berkeley, CA (United States); Brandt, Adam [Stanford Univ., CA (United States); Englander, Jacob G. [Stanford Univ., CA (United States); Hamdoun, Amro [Univ. of California of San Diego, La Jolla, CA (United States); Nicklisch, Sascha C.T. [Univ. of California of San Diego, La Jolla, CA (United States); Harrison, Robert J. [Univ. of California, San Francisco, CA (United States); Wettstein, Zachary S. [Univ. of California, San Francisco, CA (United States); Banbury, Jenner [California State Univ. Stanislaus, Turlock, CA (United States); Cypher, Brian L. [California State Univ. Stanislaus, Turlock, CA (United States); Phillips, Scott E. [California State Univ. Stanislaus, Turlock, CA (United States)

    2015-07-01

    This study is issued in three volumes. Volume I, issued in January 2015, describes how well stimulation technologies work, how and where operators deploy these technologies for oil and gas production in California, and where they might enable production in the future. Volume II, the present volume, discusses how well stimulation could affect water, atmosphere, seismic activity, wildlife and vegetation, and human health. Volume II reviews available data, and identifies knowledge gaps and alternative practices that could avoid or mitigate these possible impacts. Volume III, also issued in July 2015, presents case studies that assess environmental issues and qualitative risks for specific geographic regions. A final Summary Report summarizes key findings, conclusions and recommendations of all three volumes.

  4. An Independent Scientific Assessment of Well Stimulation in California Volume III

    Energy Technology Data Exchange (ETDEWEB)

    Long, Jane C.S. [California Council on Science and Technology, Sacramento, CA (United States); Feinstein, Laura C. [California Council on Science and Technology, Sacramento, CA (United States); Birkholzer, Jens [California Council on Science and Technology, Sacramento, CA (United States); Foxall, William [California Council on Science and Technology, Sacramento, CA (United States); Houseworth, James [California Council on Science and Technology, Sacramento, CA (United States); Jordan, Preston [California Council on Science and Technology, Sacramento, CA (United States); Lindsey, Nathaniel [California Council on Science and Technology, Sacramento, CA (United States); Maddalena, Randy [California Council on Science and Technology, Sacramento, CA (United States); McKone, Thomas [California Council on Science and Technology, Sacramento, CA (United States); Stringfellow, William [California Council on Science and Technology, Sacramento, CA (United States); Ulrich, Craig [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Heberger, Matthew [Pacific Inst., Oakland, CA (United States); Shonkoff, Seth [PSE Healthy Energy, Berkeley, CA (United States); Brandt, Adam [Stanford Univ., CA (United States); Ferrar, Kyle [The FracTracker Alliance, Oakland, CA (United States); Gautier, Donald [DonGautier LLC., Palo Alto, CA (United States); Phillips, Scott [California State Univ. Stanislaus, Turlock, CA (United States); Greenfield, Ben [Univ. of California, Berkeley, CA (United States); Jerrett, Michael L.B. [Univ. of California, Los Angeles, CA (United States)

    2015-07-01

    This study is issued in three volumes. Volume I, issued in January 2015, describes how well stimulation technologies work, how and where operators deploy these technologies for oil and gas production in California, and where they might enable production in the future. Volume II, issued in July 2015, discusses how well stimulation could affect water, atmosphere, seismic activity, wildlife and vegetation, and human health. Volume II reviews available data, and identifies knowledge gaps and alternative practices that could avoid or mitigate these possible impacts. Volume III, this volume, presents case studies that assess environmental issues and qualitative risks for specific geographic regions. The Summary Report summarizes key findings, conclusions and recommendations of all three volumes.

  5. Feasibility of disposal of high-level radioactive waste into the seabed. volume 7: Review of laboratory investigations of radionuclide migration through deep-sea sediments

    International Nuclear Information System (INIS)

    Brush, L.H.

    1988-01-01

    One of the options suggested for disposal of high-level radioactive waste resulting from the generation of nuclear power is burial beneath the deep ocean floor in geologically stable sediment formations which have no economic value. The 8-volume series provides an assessment of the technical feasibility and radiological safety of this disposal concept based on the results obtained by ten years of co-operation and information exchange among the Member countries participating in the NEA Seabed Working Group. This volume contains a review of the laboratory investigations of radionuclide migration through deep-sea sediments. In addition, it discusses the data selected for the radiological assessment, on the basis of both field and laboratory studies

  6. Advanced human-system interface design review guideline. Evaluation procedures and guidelines for human factors engineering reviews

    Energy Technology Data Exchange (ETDEWEB)

    O`Hara, J.M.; Brown, W.S. [Brookhaven National Lab., Upton, NY (United States); Baker, C.C.; Welch, D.L.; Granda, T.M.; Vingelis, P.J. [Carlow International Inc., Falls Church, VA (United States)

    1994-07-01

    Advanced control rooms will use advanced human-system interface (HSI) technologies that may have significant implications for plant safety in that they will affect the operator`s overall role in the system, the method of information presentation, and the ways in which operators interact with the system. The U.S. Nuclear Regulatory Commission (NRC) reviews the HSI aspects of control rooms to ensure that they are designed to good human factors engineering principles and that operator performance and reliability are appropriately supported to protect public health and safety. The principal guidance available to the NRC, however, was developed more than ten years ago, well before these technological changes. Accordingly, the human factors guidance needs to be updated to serve as the basis for NRC review of these advanced designs. The purpose of this project was to develop a general approach to advanced HSI review and the human factors guidelines to support. NRC safety reviews of advanced systems. This two-volume report provides the results of the project. Volume I describes the development of the Advanced HSI Design Review Guideline (DRG) including (1) its theoretical and technical foundation, (2) a general model for the review of advanced HSIs, (3) guideline development in both hard-copy and computer-based versions, and (4) the tests and evaluations performed to develop and validate the DRG. Volume I also includes a discussion of the gaps in available guidance and a methodology for addressing them. Volume 2 provides the guidelines to be used for advanced HSI review and the procedures for their use.

  7. Advanced human-system interface design review guideline. Evaluation procedures and guidelines for human factors engineering reviews

    International Nuclear Information System (INIS)

    O'Hara, J.M.; Brown, W.S.; Baker, C.C.; Welch, D.L.; Granda, T.M.; Vingelis, P.J.

    1994-07-01

    Advanced control rooms will use advanced human-system interface (HSI) technologies that may have significant implications for plant safety in that they will affect the operator's overall role in the system, the method of information presentation, and the ways in which operators interact with the system. The U.S. Nuclear Regulatory Commission (NRC) reviews the HSI aspects of control rooms to ensure that they are designed to good human factors engineering principles and that operator performance and reliability are appropriately supported to protect public health and safety. The principal guidance available to the NRC, however, was developed more than ten years ago, well before these technological changes. Accordingly, the human factors guidance needs to be updated to serve as the basis for NRC review of these advanced designs. The purpose of this project was to develop a general approach to advanced HSI review and the human factors guidelines to support. NRC safety reviews of advanced systems. This two-volume report provides the results of the project. Volume I describes the development of the Advanced HSI Design Review Guideline (DRG) including (1) its theoretical and technical foundation, (2) a general model for the review of advanced HSIs, (3) guideline development in both hard-copy and computer-based versions, and (4) the tests and evaluations performed to develop and validate the DRG. Volume I also includes a discussion of the gaps in available guidance and a methodology for addressing them. Volume 2 provides the guidelines to be used for advanced HSI review and the procedures for their use

  8. Peer review of RELAP5/MOD3 documentation

    International Nuclear Information System (INIS)

    Craddick, W.G.

    1993-01-01

    A peer review was performed on a portion of the documentation of the RELAP5/MOD3 computer code. The review was performed in two phases. The first phase was a review of Volume 3, Developmental Assessment problems, and Volume 4, Models and Correlations. The reviewers for this phase were Dr. Peter Griffith, Dr. Yassin Hassan, Dr. Gerald S. Lellouche, Dr. Marino di Marzo and Mr. Mark Wendel. The reviewers recommended a number of improvements, including using a frozen version of the code for assessment guided by a validation plan, better justification for flow regime maps and extension of models beyond their data base. The second phase was a review of Volume 6, Quality Assurance of Numerical Techniques in RELAP5/MOD3. The reviewers for the second phase were Mr. Mark Wendel and Dr. Paul T. Williams. Recommendations included correction of numerous grammatical and typographical errors and better justification for the use of Lax's Equivalence Theorem

  9. Dinámica microbial del suelo asociada a diferentes estrategias de manejo de Phytophthora cinnamomi Rands en aguacate

    Directory of Open Access Journals (Sweden)

    Joaquín Guillermo Ramírez Gil

    2013-12-01

    Full Text Available La marchitez del aguacate es la enfermedad más limitante de este cultivo, cuyo agente causal más relevante es el oomycete Phytophthora cinnamomi Rands. Es por esto que se han desarrollado diferentes estrategias para su manejo integrado, pero aún prevalece el uso de productos químicos, como única medida de manejo, generando impactos negativos en el ambiente y la salud. Uno de los efectos perjudiciales que se ocasiona es la alteración de las poblaciones microbianas en el suelo. Este trabajo estuvo encaminado a conocer la dinámica microbiana del suelo, bajo diferentes estrategias de manejo de esta enfermedad, para lo cual se midió su dinamismo mediante unidades formadoras de colonias (UFC, para hongos, bacterias y actinomicetos, a partir de muestras de suelo y rizósfera de la raíz, bajo incubación en condiciones de anaerobiosis y aerobiosis, además se midió la actividad microbiana total, en condiciones de laboratorio, como complemento se cuantificaron microorganismos como: Trichiderma spp, bacterias formadoras de endosporas (BAFE, celulolíticos, proteolíticos, amilolíticos, solubilizadores de fosfato, fijadores asimbióticos de nitrógeno y promotores del crecimiento, como Pseudomonas spp., fluorescentes. Los resultados encontrados en esta investigación, sugieren que el uso individual y combinado de mantillo orgánico, material compostado de estiércol bovino, enmienda mineral y cascarilla de arroz y la propuesta de integración; incrementan significativamente la población y actividad microbiana aerobia, en la cual se identificaron microorganismos antagonistas como, Trichiderma spp., celulolíticos, Pseudomonas spp. fluorescentes y BAFE.

  10. BMRAT reviewer acknowledgement 2015

    OpenAIRE

    Lili Hami

    2016-01-01

    Contributing reviewers The editors of Biomedical Research and Therapy would like to thank all our reviewers who have contributed to the journal in Volume 2 (2015). [Biomed Res Ther 2016; 3(2.000): 528-532

  11. Peer review statement

    Science.gov (United States)

    2018-03-01

    All papers published in this volume of Journal of Physics: Conference Series have been peer reviewed through processes administered by the proceedings Editors. Reviews were conducted by expert referees to the professional and scientific standards expected of a proceedings journal published by IOP Publishing.

  12. Handbook on the physics and chemistry of rare earths: Volume 17

    International Nuclear Information System (INIS)

    Gschneidner, K.A. Jr; Eyring, L.; Choppin, G.R.; Lander, G.H.

    1993-10-01

    This volume of the handbook is the first of a three volume set of reviews devoted to the interrelationships, similarities, differences and contrasts of the lanthanide and actinide series of elements. The volume contains eight chapters (numbered 110-117) concerned with some of the physical aspects of lanthanide and actinide series. The first three chapters are theoretical in nature and the last five are more heavily oriented towards experimental studies

  13. Oak Ridge Reservation environmental report for 1992. Volume 1: Narrative

    Energy Technology Data Exchange (ETDEWEB)

    Koncinski, W.S. [ed.

    1993-09-01

    The two volumes of this report present data and supporting narratives regarding the impact of the US Department of Energy`s (DOE`s) Oak Ridge Reservation (ORR) on its environs and the public during 1992. This Volume (Volume 1) includes all narrative descriptions, summaries, and conclusions and is intended to be a ``stand-alone`` report for the reader who does not want to review in detail all of the 1992 data for the ORR. Volume 2 includes the detailed data in formats that ensure all the environmental data are represented. Narratives are not included in Vol. 2.

  14. Ouabain-Induced Cytoplasmic Vesicles and Their Role in Cell Volume Maintenance

    Directory of Open Access Journals (Sweden)

    M. A. Russo

    2015-01-01

    Full Text Available Cellular swelling is controlled by an active mechanism of cell volume regulation driven by a Na+/K+-dependent ATPase and by aquaporins which translocate water along the osmotic gradient. Na+/K+-pump may be blocked by ouabain, a digitalic derivative, by inhibition of ATP, or by drastic ion alterations of extracellular fluid. However, it has been observed that some tissues are still able to control their volume despite the presence of ouabain, suggesting the existence of other mechanisms of cell volume control. In 1977, by correlating electron microscopy observation with ion and water composition of liver slices incubated in different metabolic conditions in the presence or absence of ouabain, we observed that hepatocytes were able to control their volume extruding water and recovering ion composition in the presence of ouabain. In particular, hepatocytes were able to sequester ions and water in intracellular vesicles and then secrete them at the bile canaliculus pole. We named this “vesicular mechanism of cell volume control.” Afterward, this mechanism has been confirmed by us and other laboratories in several mammalian tissues. This review summarizes evidences regarding this mechanism, problems that are still pending, and questions that need to be answered. Finally, we shortly review the importance of cell volume control in some human pathological conditions.

  15. Ion-selective electrode reviews

    CERN Document Server

    Thomas, J D R

    1982-01-01

    Ion-Selective Electrode Reviews, Volume 3, provides a review of articles on ion-selective electrodes (ISEs). The volume begins with an article on methods based on titration procedures for surfactant analysis, which have been developed for discrete batch operation and for continuous AutoAnalyser use. Separate chapters deal with detection limits of ion-selective electrodes; the possibility of using inorganic ion-exchange materials as ion-sensors; and the effect of solvent on potentials of cells with ion-selective electrodes. Also included is a chapter on advances in calibration procedures, the d

  16. Seismic margin review of the Maine Yankee Atomic Power Station: Fragility analysis

    International Nuclear Information System (INIS)

    Ravindra, M.K.; Hardy, G.S.; Hashimoto, P.S.; Griffin, M.J.

    1987-03-01

    This Fragility Analysis is the third of three volumes for the Seismic Margin Review of the Maine Yankee Atomic Power Station. Volume 1 is the Summary Report of the first trial seismic margin review. Volume 2, Systems Analysis, documents the results of the systems screening for the review. The three volumes are part of the Seismic Margins Program initiated in 1984 by the Nuclear Regulatory Commission (NRC) to quantify seismic margins at nuclear power plants. The overall objectives of the trial review are to assess the seismic margins of a particular pressurized water reactor, and to test the adequacy of this review approach, quantification techniques, and guidelines for performing the review. Results from the trial review will be used to revise the seismic margin methodology and guidelines so that the NRC and industry can readily apply them to assess the inherent quantitative seismic capacity of nuclear power plants

  17. Seismic margin review of the Maine Yankee Atomic Power Station: Fragility analysis

    Energy Technology Data Exchange (ETDEWEB)

    Ravindra, M. K.; Hardy, G. S.; Hashimoto, P. S.; Griffin, M. J.

    1987-03-01

    This Fragility Analysis is the third of three volumes for the Seismic Margin Review of the Maine Yankee Atomic Power Station. Volume 1 is the Summary Report of the first trial seismic margin review. Volume 2, Systems Analysis, documents the results of the systems screening for the review. The three volumes are part of the Seismic Margins Program initiated in 1984 by the Nuclear Regulatory Commission (NRC) to quantify seismic margins at nuclear power plants. The overall objectives of the trial review are to assess the seismic margins of a particular pressurized water reactor, and to test the adequacy of this review approach, quantification techniques, and guidelines for performing the review. Results from the trial review will be used to revise the seismic margin methodology and guidelines so that the NRC and industry can readily apply them to assess the inherent quantitative seismic capacity of nuclear power plants.

  18. TPX: Contractor preliminary design review. Volume 1, Presentation and design description. Final report

    International Nuclear Information System (INIS)

    Hartman, D.; Naumovich; Walstrom, P.; Clarkson, I.; Schultheiss, J.; Burger, A.

    1995-01-01

    This first volume of the five volume set begins with a CPDR overview and then details the PF magnet system, manufacturing R ampersand D, Westinghouse R ampersand D, the central solenoid, the PF 5 ring coil, the PF 6/7 ring coil, quality assurance, and the system design description

  19. Normal and refractory concretes for LMFBR applications. Volume 1. Review of literature on high-temperature behavior of portland cement and refractory concretes. Final report

    International Nuclear Information System (INIS)

    Bazant, Z.P.; Chern, J.C.; Abrams, M.S.; Gillen, M.P.

    1982-06-01

    The extensive literature on the properties and behavior at elevated temperature of portland cement concrete and various refractory concretes was reviewed to collect in concise form the physical and chemical properties of castable refractory concretes and of conventional portland cement concretes at elevated temperature. This survey, together with an extensive bibliography of source documents, is presented in Volume 1. A comparison was made of these properties, the relative advantages of the various concretes was evaluated for possible liquid metal fast breeder reactor applications, and a selection was made of several materials of interest for such applications. Volume 2 concludes with a summary of additional knowledge needed to support such uses of these materials together with recommendations on research to provide that knowledge

  20. Editorial, Volume 5, Issue 1

    Directory of Open Access Journals (Sweden)

    Kristy L. Archuleta

    2014-08-01

    Full Text Available Welcome to Volume 5, Issue 1 of the Journal of Financial Therapy! In this issue, four scholarly papers are presented along with two profiles and a book review. These four papers address very important issues, such as mental health therapists’ competency in working with financial issues, financial stress of college students, parental messages about money, and financial advice media.

  1. Does Peer Review of Radiation Plans Affect Clinical Care? A Systematic Review of the Literature

    International Nuclear Information System (INIS)

    Brunskill, Kelsey; Nguyen, Timothy K.; Boldt, R. Gabriel; Louie, Alexander V.; Warner, Andrew; Marks, Lawrence B.; Palma, David A.

    2017-01-01

    Purpose: Peer review is a recommended component of quality assurance in radiation oncology; however, it is resource-intensive and its effect on patient care is not well understood. We conducted a systematic review of the published data to assess the reported clinical impact of peer review on radiation treatment plans. Methods and Materials: A systematic review of published English studies was performed in accordance with the PRISMA guidelines using the MEDLINE and EMBASE databases and abstracts published from major radiation oncology scientific meeting proceedings. For inclusion, the studies were required to report the effect of peer review on ≥1 element of treatment planning (eg, target volume or organ-at-risk delineation, dose prescription or dosimetry). Results: The initial search strategy identified 882 potentially eligible studies, with 11 meeting the inclusion criteria for full-text review and final analysis. Across a total of 11,491 patient cases, peer review programs led to modifications in a weighted mean of 10.8% of radiation treatment plans. Five studies differentiated between major and minor changes and reported weighted mean rates of change of 1.8% and 7.3%, respectively. The most common changes were related to target volume delineation (45.2% of changed plans), dose prescription or written directives (24.4%), and non-target volume delineation or normal tissue sparing (7.5%). Conclusions: Our findings suggest that peer review leads to changes in clinical care in approximately 1 of every 9 cases overall. This is similar to the reported rates of change in peer review studies from other oncology-related specialties, such as radiology and pathology.

  2. Predictive and prognostic value of tumor volume and its changes during radical radiotherapy of stage III non-small cell lung cancer. A systematic review

    International Nuclear Information System (INIS)

    Kaesmann, Lukas; Niyazi, Maximilian; Fleischmann, Daniel; Blanck, Oliver; Baumann, Rene; Baues, Christian; Klook, Lisa; Rosenbrock, Johannes; Trommer-Nestler, Maike; Dobiasch, Sophie; Eze, Chukwuka; Gauer, Tobias; Goy, Yvonne; Giordano, Frank A.; Sautter, Lisa; Hausmann, Jan; Henkenberens, Christoph; Kaul, David; Thieme, Alexander H.; Krug, David; Schmitt, Daniela; Maeurer, Matthias; Panje, Cedric M.; Suess, Christoph; Ziegler, Sonia; Ebert, Nadja; Medenwald, Daniel; Ostheimer, Christian

    2018-01-01

    Lung cancer remains the leading cause of cancer-related mortality worldwide. Stage III non-small cell lung cancer (NSCLC) includes heterogeneous presentation of the disease including lymph node involvement and large tumour volumes with infiltration of the mediastinum, heart or spine. In the treatment of stage III NSCLC an interdisciplinary approach including radiotherapy is considered standard of care with acceptable toxicity and improved clinical outcome concerning local control. Furthermore, gross tumour volume (GTV) changes during definitive radiotherapy would allow for adaptive replanning which offers normal tissue sparing and dose escalation. A literature review was conducted to describe the predictive value of GTV changes during definitive radiotherapy especially focussing on overall survival. The literature search was conducted in a two-step review process using PubMed registered /Medline registered with the key words ''stage III non-small cell lung cancer'' and ''radiotherapy'' and ''tumour volume'' and ''prognostic factors''. After final consideration 17, 14 and 9 studies with a total of 2516, 784 and 639 patients on predictive impact of GTV, GTV changes and its impact on overall survival, respectively, for definitive radiotherapy for stage III NSCLC were included in this review. Initial GTV is an important prognostic factor for overall survival in several studies, but the time of evaluation and the value of histology need to be further investigated. GTV changes during RT differ widely, optimal timing for re-evaluation of GTV and their predictive value for prognosis needs to be clarified. The prognostic value of GTV changes is unclear due to varying study qualities, re-evaluation time and conflicting results. The main findings were that the clinical impact of GTV changes during definitive radiotherapy is still unclear due to heterogeneous study designs with varying quality

  3. Report on enrichment work at AB Atomenergi, 1965-1978

    International Nuclear Information System (INIS)

    Maartensson, M.

    1978-11-01

    A review of the Rand D performed at AB Atomenergi (now Studsvik Energiteknik AB) in the field of enrichment during the period 1965-1978. The report also describes the international development, and discusses the possibilities for continued Swedish efforts in this area. (L.E.)

  4. Extracorporeal membrane oxygenation (ECMO) as a treatment strategy for severe acute respiratory distress syndrome (ARDS) in the low tidal volume era: A systematic review.

    Science.gov (United States)

    Tillmann, Bourke W; Klingel, Michelle L; Iansavichene, Alla E; Ball, Ian M; Nagpal, A Dave

    2017-10-01

    To evaluate the hospital survival in patients with severe ARDS managed with ECMO and low tidal volume ventilation as compared to patients managed with low tidal volume ventilation alone. Electronic databases were searched for studies of at least 10 adult patients with severe ARDS comparing the use of ECMO with low tidal volume ventilation to mechanical ventilation with a low tidal volume alone. Only studies reporting hospital or ICU survival were included. All identified studies were assessed independently by two reviewers. Of 1782 citations, 27 studies (n=1674) met inclusion criteria. Hospital survival for ECMO patients ranged from 33.3 to 86%, while survival with conventional therapy ranged from 36.3 to 71.2%. Five studies were identified with appropriate control groups allowing comparison, but due to the high degree of variability between studies (I 2 =63%), their results could not be pooled. Two of these studies demonstrated a significant difference, both favouring ECMO over conventional therapy. Given the lack of studies with appropriate control groups, our confidence in a difference in outcome between the two therapies remains weak. Future studies on the use of ECMO for severe ARDS are needed to clarify the role of ECMO in this disease. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Olympic Training Film Profiles. Volume III.

    Science.gov (United States)

    1971

    Approximately 250 instructional films are described in Volume Three (1970-1971) of this review. After an introduction which considers film discussions from the instructor's point of view and offers some ideas for conducting a film showing and ordering the films, profiles of the films are presented grouped under such areas as management…

  6. Volume of hydration in terminal cancer patients.

    Science.gov (United States)

    Bruera, E; Belzile, M; Watanabe, S; Fainsinger, R L

    1996-03-01

    In this retrospective study we reviewed the volume and modality of hydration of consecutive series of terminal cancer patients in two different settings. In a palliative care unit 203/290 admitted patients received subcutaneous hydration for 12 +/- 8 days at a daily volume of 1015 +/- 135 ml/day. At the cancer center, 30 consecutive similar patients received intravenous hydration for 11.5 +/- 5 days (P > 0.2) but at a daily volume of 2080 +/- 720 ml/day (P palliative care unit patients required discontinuation of hydration because of complications. Hypodermoclysis was administered mainly as a continuous infusion, an overnight infusion, or in one to three 1-h boluses in 62 (31%), 98 (48%) and 43 (21%) patients, respectively. Our findings suggest that, in some settings, patients may be receiving excessive volumes of hydration by less comfortable routes such as the intravenous route. Increased education and research in this area are badly needed.

  7. Journal of Sustainable Development of Energy, Water and Environment Systems – Volume IV

    Directory of Open Access Journals (Sweden)

    Neven Duić

    2016-12-01

    In total 32 manuscripts were published in Volume IV, all of them reviewed by at least two reviewers. The Journal of Sustainable Development of Energy, Water and Environment Systems would like to thank reviewers for their contribution to the quality of the published manuscripts.

  8. Sensors and signal transduction pathways in vertebrate cell volume regulation

    DEFF Research Database (Denmark)

    Hoffmann, Else K; Pedersen, Stine F

    2006-01-01

    The ability to control cell volume is fundamental for proper cell function. This review highlights recent advances in the understanding of the complex sequences of events by which acute cell volume perturbation alters the activity of osmolyte transport proteins in cells from vertebrate organisms...... will be discussed. In contrast to the simple pathway of osmosensing in yeast, cells from vertebrate organisms appear to exhibit multiple volume sensing systems, the specific mechanism(s) activated being cell type- and stimulus-dependent. Candidate sensors include integrins and growth factor receptors, while other...

  9. Volume reduction, a safer and cheaper way of radwaste management

    International Nuclear Information System (INIS)

    Mergan, L.M.; Cordier, J.P.; Storrer, J.A.

    1979-01-01

    Development of 'Volume Reduction' has demonstrated that it is a safer and cheaper radwaste management method. Safer, because of several advantages: decrease of solidified product volume, satisfactory product properties, absence of free water, better control of process parameters, increased encapsulation efficiency ... The corresponding impact on the waste management costs, results in important savings on different factors, as well as regards the operational costs as the investment expenses. Economy in the range of BF 35.000 per m 3 of incoming waste is achievable. The main volume reduction techniques readily available are briefly reviewed

  10. Small-Volume Injections: Evaluation of Volume Administration Deviation From Intended Injection Volumes.

    Science.gov (United States)

    Muffly, Matthew K; Chen, Michael I; Claure, Rebecca E; Drover, David R; Efron, Bradley; Fitch, William L; Hammer, Gregory B

    2017-10-01

    In the perioperative period, anesthesiologists and postanesthesia care unit (PACU) nurses routinely prepare and administer small-volume IV injections, yet the accuracy of delivered medication volumes in this setting has not been described. In this ex vivo study, we sought to characterize the degree to which small-volume injections (≤0.5 mL) deviated from the intended injection volumes among a group of pediatric anesthesiologists and pediatric postanesthesia care unit (PACU) nurses. We hypothesized that as the intended injection volumes decreased, the deviation from those intended injection volumes would increase. Ten attending pediatric anesthesiologists and 10 pediatric PACU nurses each performed a series of 10 injections into a simulated patient IV setup. Practitioners used separate 1-mL tuberculin syringes with removable 18-gauge needles (Becton-Dickinson & Company, Franklin Lakes, NJ) to aspirate 5 different volumes (0.025, 0.05, 0.1, 0.25, and 0.5 mL) of 0.25 mM Lucifer Yellow (LY) fluorescent dye constituted in saline (Sigma Aldrich, St. Louis, MO) from a rubber-stoppered vial. Each participant then injected the specified volume of LY fluorescent dye via a 3-way stopcock into IV tubing with free-flowing 0.9% sodium chloride (10 mL/min). The injected volume of LY fluorescent dye and 0.9% sodium chloride then drained into a collection vial for laboratory analysis. Microplate fluorescence wavelength detection (Infinite M1000; Tecan, Mannedorf, Switzerland) was used to measure the fluorescence of the collected fluid. Administered injection volumes were calculated based on the fluorescence of the collected fluid using a calibration curve of known LY volumes and associated fluorescence.To determine whether deviation of the administered volumes from the intended injection volumes increased at lower injection volumes, we compared the proportional injection volume error (loge [administered volume/intended volume]) for each of the 5 injection volumes using a linear

  11. Technical evaluation of the ATI volume reduction and bitumen solidification topical report

    International Nuclear Information System (INIS)

    Henscheid, J.W.; Young, T.E.

    1985-01-01

    This report summarizes EG and G Idaho's review of the Associated Technologies Inorporated (ATI) topical report on a Volume Reduction and Bitumen Solidification System. The review evaluated compliance with pertinent codes, standards and regulations. The initial review was discussed with ATI, and all outstanding issues resolved before this final evaluation was made

  12. The NIHR Invention for Innovation (i4i) Programme: A Review of Progress and Contributions to Innovation in Healthcare Technologies.

    Science.gov (United States)

    Marjanovic, Sonja; Krapels, Joachim; Sousa, Sonia; Castle-Clarke, Sophie; Horvath, Veronika; Chataway, Joanna

    2015-11-30

    The National Institute for Health Research (NIHR) Invention for Innovation (i4i) programme supports the development of innovative medical technologies for patient benefit. The i4i product development stream involves collaborative projects between at least two partners from academia, the NHS and industry. Medical technology innovators apply for funding for one to three years, through a peer review-based process that includes presentation to a selection panel. The funding and business advice provided by i4i support the development of early-stage innovations, generally at proof of concept and prototype stages. Since its inception the product development stream has identified and supported 170 projects, led by 146 principal investigators (PIs). RAND Europe evaluated the programme, with the aim of identifying its outputs and impacts and examining the factors influencing performance. The evaluation findings should help inform the future of the programme. The evaluation used a multi-method approach, including a focused review of background information from i4i, scoping interviews with key informants, a survey of programme participants and case studies of projects representing diverse technologies and health needs.

  13. Impacts of Outer Continental Shelf (OCS) development on recreation and tourism. Volume 3. Detailed methodology

    Energy Technology Data Exchange (ETDEWEB)

    1987-04-01

    The final report for the project is presented in five volumes. This volume, Detailed Methodology Review, presents a discussion of the methods considered and used to estimate the impacts of Outer Continental Shelf (OCS) oil and gas development on coastal recreation in California. The purpose is to provide the Minerals Management Service with data and methods to improve their ability to analyze the socio-economic impacts of OCS development. Chapter II provides a review of previous attempts to evaluate the effects of OCS development and of oil spills on coastal recreation. The review also discusses the strengths and weaknesses of different approaches and presents the rationale for the methodology selection made. Chapter III presents a detailed discussion of the methods actually used in the study. The volume contains the bibliography for the entire study.

  14. Hybrid vehicle potential assessment. Volume 7: Hybrid vehicle review

    Science.gov (United States)

    Leschly, K. O.

    1979-01-01

    Review of hybrid vehicles built during the past ten years or planned to be built in the near future is presented. An attempt is made to classify and analyze these vehicles to get an overall picture of their key characteristics. The review includes onroad hybrid passenger cars, trucks, vans, and buses.

  15. Large-volume injection in gas chromatographic trace analysis using temperature-programmable (PTV) injectors

    NARCIS (Netherlands)

    Mol, J.G.J.; Janssen, J.G.M.; Cramers, C.A.M.G.; Brinkman, U.A.T.

    1996-01-01

    The use of programmed-temperature vaporising (PTV) injectors for large-volume injection in capillary gas chromatography is briefly reviewed. The principles and optimisation of large-volume PTV injection are discussed. Guidelines are given for selection of the PTV conditions and injection mode for

  16. Solar technology assessment project. Volume 6: Photovoltaic technology assessment

    Science.gov (United States)

    Backus, C. E.

    1981-04-01

    Industrial production of photovoltaic systems and volume of sales are reviewed. Low cost silicon production techniques are reviewed, including the Czochralski process, heat exchange method, edge defined film fed growth, dentritic web growth, and silicon on ceramic process. Semicrystalline silicon, amorphous silicon, and low cost poly-silicon are discussed as well as advanced materials and concentrator systems. Balance of system components beyond those needed to manufacture the solar panels are included. Nontechnical factors are assessed. The 1986 system cost goals are briefly reviewed.

  17. 8th conference on Finite Volumes for Complex Applications

    CERN Document Server

    Omnes, Pascal

    2017-01-01

    This first volume of the proceedings of the 8th conference on "Finite Volumes for Complex Applications" (Lille, June 2017) covers various topics including convergence and stability analysis, as well as investigations of these methods from the point of view of compatibility with physical principles. It collects together the focused invited papers comparing advanced numerical methods for Stokes and Navier–Stokes equations on a benchmark, as well as reviewed contributions from internationally leading researchers in the field of analysis of finite volume and related methods, offering a comprehensive overview of the state of the art in the field. The finite volume method in its various forms is a space discretization technique for partial differential equations based on the fundamental physical principle of conservation, and recent decades have brought significant advances in the theoretical understanding of the method. Many finite volume methods preserve further qualitative or asymptotic properties, including m...

  18. Vad är den främst avgörande faktorn vid privatkundens val av marginalbank? : en studie om hur demografiska skillnader påverkar privatkunders val av marginalbank samt se hur deras val kan användas vid segmentering

    OpenAIRE

    Lindh, Jenni; Persson, Frida

    2012-01-01

    Syfte: Syftet med detta examensarbete är att förklara vad som är den främst avgörande faktorn vid privatkundens val av marginalbank, genom att jämföra med demografiska variabler samt hur deras val kan användas vid segmentering. Dessutom vill vi titta på vilka typer av banker privatkunder har. Metod: För att nå fram till resultat för analysen har ett positivistiskt angreppssätt och en deduktiv ansats använts. Det empiriska materialet är baserat på en enkätundersökning gjord på personer i Hässl...

  19. AFRICAN JOURNAL OF ECONOMIC REVIEW

    African Journals Online (AJOL)

    Dr Kazungu

    African Journal of Economic Review, Volume VI, Issue I, January 2018. 33. Analyzing .... Previous analysis of inflation in Nigeria as a macroeconomic variable have focused at its impact ..... International Journal of Finance and Economics 2, 225-235. ... Quantitative and Qualitative Analysis in Social Sciences Volume 1,.

  20. Bibliography of Utah radioactive occurrences. Volume I

    International Nuclear Information System (INIS)

    Doelling, H.H.

    1983-07-01

    The references in this bibliography were assembled by reviewing published bibliographies of Utah geology, unpublished reports of the US Geological Survey and the Department of Energy, and various university theses. Each of the listings is cross-referenced by location and subject matter. This report is published in two volumes

  1. Bibliography of Utah radioactive occurrences. Volume II

    International Nuclear Information System (INIS)

    Doelling, H.H.

    1983-07-01

    The references in this bibliography were assembled by reviewing published bibliographies of Utah geology, unpublished reports of the US Geological Survey and the Department of Energy, and various university theses. Each of the listings is cross-referenced by location and subject matter. This report is published in two volumes

  2. Local and Global Illumination in the Volume Rendering Integral

    Energy Technology Data Exchange (ETDEWEB)

    Max, N; Chen, M

    2005-10-21

    This article is intended as an update of the major survey by Max [1] on optical models for direct volume rendering. It provides a brief overview of the subject scope covered by [1], and brings recent developments, such as new shadow algorithms and refraction rendering, into the perspective. In particular, we examine three fundamentals aspects of direct volume rendering, namely the volume rendering integral, local illumination models and global illumination models, in a wavelength-independent manner. We review the developments on spectral volume rendering, in which visible light are considered as a form of electromagnetic radiation, optical models are implemented in conjunction with representations of spectral power distribution. This survey can provide a basis for, and encourage, new efforts for developing and using complex illumination models to achieve better realism and perception through optical correctness.

  3. Formative Review of the Critical Television Viewing Skills Curriculum for Secondary Schools. Volume I: Final Report. Volume II: Teacher's Guide: Reviewers' Suggested Revisions.

    Science.gov (United States)

    Wheeler, Patricia; And Others

    This formative review of a project designed to help high school students become more discriminating television viewers (1) presents a description of the curriculum designed during the project to foster critical television viewing in teenagers, (2) outlines the major tasks involved in the formative review of the curriculum, and (3) presents and…

  4. Review of energy policy

    International Nuclear Information System (INIS)

    1986-11-01

    Following the accident at the Chernobyl reactor in April 1986, the 1986 Annual Delegate Conference of the Institution of Professional Civil Servants set up a Working Party to review the Institution's energy policy, including safety and environmental factors. The review is presented in two volumes as the basis for discussion by the members. Volume I is the main report. Section A, the introduction, includes a summary of the detailed conclusions and recommendations of the Working Party. Section B (chapters 4-12) concerns all aspects of nuclear power including fuel reprocessing and waste management. Section C (chapters 13-16) considers the alternatives to nuclear power and Section D (chapters 17-24) looks at the economic and social aspects of energy policy. The appendices, which contain the detailed technical and source information used by the Working Party in reaching its conclusions, are printed separately in Volume II. (UK)

  5. Progress in Ultrafast Intense Laser Science Volume V

    CERN Document Server

    Yamanouchi, Kaoru; Ledingham, Kenneth

    2010-01-01

    The PUILS series delivers up-to-date reviews of progress in Ultrafast Intense Laser Science, a newly emerging interdisciplinary research field spanning atomic and molecular physics, molecular science, and optical science, which has been stimulated by the recent developments in ultrafast laser technologies. Each volume compiles peer-reviewed articles authored by researchers at the forefront of each their own subfields of UILS. Every chapter opens with an overview of the topics to be discussed, so that researchers unfamiliar to the subfield, as well as graduate students, can grasp the importance and attractions of the research topic at hand; these are followed by reports of cutting-edge discoveries. This fifth volume covers a broad range of topics from this interdisciplinary research field, focusing on coherent responses of gaseous and condensed matter to ultrashort intense laser pulses, propagation of intense laser pulses, and laser-plasma interaction and its applications.

  6. Report on the Survey of the Design Review of New Reactor Applications. Volume 4: Reactor Coolant and Associated Systems

    International Nuclear Information System (INIS)

    Downey, Steven; Monninger, John; Nevalainen, Janne; Joyer, Philippe; Koley, Jaharlal; Kawamura, Tomonori; Chung, Yeon-Ki; Haluska, Ladislav; Persic, Andreja; Reierson, Craig; Monninger, John; Choi, Young-Joon; )

    2017-01-01

    At the tenth meeting of the Committee on Nuclear Regulatory Activities (CNRA) Working Group on the Regulation of New Reactors (WGRNR) in March 2013, the Working Group agreed to present the responses to the Second Phase, or Design Phase, of the licensing process survey as a multi-volume text. As such, each report will focus on one of the eleven general technical categories covered in the survey. The general technical categories were selected to conform to the topics covered in the International Atomic Energy Agency (IAEA) Safety Guide GS-G-4.1. This report provides a discussion of the survey responses related to the Reactor Coolant and Associated Systems category. The Reactor Coolant and Associated Systems category includes the following technical topics: overpressure protection, reactor coolant pressure boundary, reactor vessel, and design of the reactor coolant system. For each technical topic, the member countries described the information provided by the applicant, the scope and level of detail of the technical review, the technical basis for granting regulatory authorisation, the skill sets required and the level of effort needed to perform the review. Based on a comparison of the information provided by the member countries in response to the survey, the following observations were made: - Although the description of the information provided by the applicant differs in scope and level of detail among the member countries that provided responses, there are similarities in the information that is required. - All of the technical topics covered in the survey are reviewed in some manner by all of the regulatory authorities that provided responses. - It is common to consider operating experience and lessons learnt from the current fleet during the review process. - The most commonly and consistently identified technical expertise needed to perform design reviews related to this category are mechanical engineering and materials engineering. The complete survey

  7. LLE Review Quarterly Report January - March 2012. Volume 130

    Energy Technology Data Exchange (ETDEWEB)

    Shvydky, Alex [Univ. of Rochester, NY (United States). Lab. for Laser Energetics

    2012-03-01

    This volume of the LLE Review, covering January–March 2012, features “OMEGA Polar-Drive Target Designs,” by P. B. Radha, J. A. Marozas, F. J. Marshall, A. Shvydky, T. J. B. Collins, V. N. Goncharov, R. L. McCrory, P. W. McKenty, D. D. Meyerhofer, T. C. Sangster, and S. Skupsky. This article (p. 57) describes low-adiabat, cryogenic-deuterium–tritium, and warm-plastic-shell polar-drive (PD)–implosion designs for the OMEGA laser. The designs are at two different on-target laser intensities, each at a different in-flight aspect ratio (IFAR). The first design permits one to study implosion energetics and target performance closer to ignition-relevant intensities (7 X 1014 W/cm2 at the quarter-critical surface), where nonlocal heat conduction and laser–plasma interactions can play an important role, but at lower values of IFAR (~22). The second design permits one to study implosion energetics and target performance at a lower intensity (3 X 1014 W/cm2) but at higher IFAR (~32), where the shell instability can play an important role. The higher IFAR designs are accessible on the existing OMEGA Laser System only at lower intensities. Implosions at ignition-relevant intensities can be obtained only by reducing target radius, although only at smaller values of IFAR. Polar-drive geometry requires repointing the laser beams to improve shell symmetry. The higher-intensity designs optimize target performance by repointing beams to a lesser extent and compensate for the reduced equatorial drive by increasing beam energies for the repointed beams and using custom beam profiles that improve equatorial illumination at the expense of irradiation at higher latitudes. These designs will be studied when new phase plates for the OMEGA Laser System, corresponding to the smaller target radii and custom beam profiles, are obtained. Implosion results from the combined set of high-intensity and high-IFAR implosions should yield valuable

  8. Minimally invasive non-surgical lung volume reduction

    International Nuclear Information System (INIS)

    Shen Liming; Zhou Dayong; Shen Junkang

    2006-01-01

    Minimally invasive treatment with lung volume reduction is the promising future for severe pulmonary emphysema patients. With emerging and improving of new techniques and instruments, it would become an important choice for managing severe emphysema. A comprehensive review is here documented through the correlative techniques, instruments, new achievements and latest research work. (authors)

  9. Handbook of plant cell culture. Volume 2. Crop species

    Energy Technology Data Exchange (ETDEWEB)

    Sharp, W.R.; Evans, D.A.; Ammirato, P.V.; Yamada, Y. (eds.)

    1984-01-01

    In this volume the state-of-the-art plant cell culture techniques described in the first volume are applied to several agricultural and horticultural crops. In 21 chapters, they include maize, oats, wheat, beans, red clover and other forage legumes, asparagus, celery, cassava, sweet potato, banana, pawpaw, apple, grapes, conifers, date palm, rubber, sugarcane and tobacco. Each chapter contains (1) detailed protocols to serve as the foundation for current research, (2) a critical review of the literature, and (3) in-depth evaluations of the potential shown by plant cell culture for crop improvement. The history and economic importance of each crop are discussed. This volume also includes an essay, ''Oil from plants'', by M. Calvin.

  10. The adoption of new smart-grid technologies incentives, outcomes, and opportunities

    CERN Document Server

    Guo, Christopher; Narayanan, Anu

    2015-01-01

    RAND Corporation researchers review the current technical, regulatory, and economic context of the electricity market and theoretical benefits of developing a smart grid; discuss some entrepreneurial opportunities associated with smart-grid data; examine empirical evidence related to smart-grid adoption and implementation; and offer policy suggestions for overcoming identified barriers.

  11. Reorganizing U.S. Domestic Intelligence: Assessing the Options

    Science.gov (United States)

    2008-01-01

    terror remains a parlous enterprise. Surely, having a separate service is no panacea for interagency con- flict: Britain’s domestic service, MI-5, and...Paradigm: The Guilt By Association Critique,” Michigan Law Review, Vol. 101, No. 6, May 2003, pp. 1408–1452. Clarke, Richard A., and Rand Beers

  12. Relaxation volumes of self-interstitial-atoms and vacancies in metals

    International Nuclear Information System (INIS)

    Ehrhart, P.

    1983-01-01

    Experimental results for the relaxation volumes of self-interstitial-atoms and vacancies as obtained after low temperature irradiation of different metals are reviewed. For fcc metals the relaxation volumes of the SIA's are very similar: ΔVsup(rel) = 1.6 +- 0.3 atomic volumes. This value is valid as well for the pure fcc metals (Al, Cu, Ni) as for different alloys. Vacancy relaxation volumes are small and vary between: ΔVsup(rel) = -0.05 and -0.25 atomic volumes. For bcc metals (Fe, Mo) the relaxation volume of the SIA is significantly smaller: ΔVsup(rel) = 1.1 +- 0.2 atomic volumes. In spite of the obvious similarity of the close-packed fcc and hcp structures, the SIA parameters for hcp metals are much different: ΔVsup(rel) = 3.5 for Zn, ΔVsup(rel) = 1.5 for Co and ΔVsup(rel) = 0.6 at. vol. for Zr. Vacancy relaxation volumes seem to be small as in cubic metals. The influence of lattice nonharmonicity on the validity of an extrapolation of the values determined at 6 K to higher temperatures is discussed. (author)

  13. LWR risk management by safety R and D

    International Nuclear Information System (INIS)

    El-Sheikh, K.A.; Damon, D.R.; Temme, M.I.

    1982-01-01

    This paper presents a methodology which has been developed for selecting LWR safety RandD projects. The methodology provides ranking of the RandD projects and the RandD budget allocation which minimizes public risk. The methodology contains procedures to identify institutional, organizational, legal, and contractual factors which affect the probabilities of success and use of RandD projects so that these factors can be evaluated and possibly managed.The methodology also contains a nonlinear optimization code to provide the optimum selection of RandD projects and evaluate the sensitivity of this selection to uncertainity in the input data. Application of the methodology to a test case has shown that: 1) commonly used schemes for ranking RandD projects do not necessarily lead to the optimum selection, and 2) the optimum selection is not necessarily strongly sensitive to uncertainty in the input data

  14. 2013 BNL Site Environmental Report. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Ratel, K.; Remien, J.; Pohlot, P.; Williams, J.; Green, T.; Paquette, P.; Dorsch, W.; Welty, T.; Burke, J.

    2014-10-01

    A summary of Brookhaven National Laboratory’s (BNL) Site Environmental Report, meant to inform the public, regulators, employees, and other stakeholders of the Laboratory’s environmental performance in the lab’s surrounding area during the calendar year. The review is comprised of multiple volumes relevant to environmental data/environmental management performance and groundwater status report.

  15. Waste disposal options report. Volume 2

    International Nuclear Information System (INIS)

    Russell, N.E.; McDonald, T.G.; Banaee, J.; Barnes, C.M.; Fish, L.W.; Losinski, S.J.; Peterson, H.K.; Sterbentz, J.W.; Wenzel, D.R.

    1998-02-01

    Volume 2 contains the following topical sections: estimates of feed and waste volumes, compositions, and properties; evaluation of radionuclide inventory for Zr calcine; evaluation of radionuclide inventory for Al calcine; determination of k eff for high level waste canisters in various configurations; review of ceramic silicone foam for radioactive waste disposal; epoxides for low-level radioactive waste disposal; evaluation of several neutralization cases in processing calcine and sodium-bearing waste; background information for EFEs, dose rates, watts/canister, and PE-curies; waste disposal options assumptions; update of radiation field definition and thermal generation rates for calcine process packages of various geometries-HKP-26-97; and standard criteria of candidate repositories and environmental regulations for the treatment and disposal of ICPP radioactive mixed wastes

  16. Waste disposal options report. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    Russell, N.E.; McDonald, T.G.; Banaee, J.; Barnes, C.M.; Fish, L.W.; Losinski, S.J.; Peterson, H.K.; Sterbentz, J.W.; Wenzel, D.R.

    1998-02-01

    Volume 2 contains the following topical sections: estimates of feed and waste volumes, compositions, and properties; evaluation of radionuclide inventory for Zr calcine; evaluation of radionuclide inventory for Al calcine; determination of k{sub eff} for high level waste canisters in various configurations; review of ceramic silicone foam for radioactive waste disposal; epoxides for low-level radioactive waste disposal; evaluation of several neutralization cases in processing calcine and sodium-bearing waste; background information for EFEs, dose rates, watts/canister, and PE-curies; waste disposal options assumptions; update of radiation field definition and thermal generation rates for calcine process packages of various geometries-HKP-26-97; and standard criteria of candidate repositories and environmental regulations for the treatment and disposal of ICPP radioactive mixed wastes.

  17. Energy-efficient buildings program evaluations. Volume 2: Evaluation summaries

    Energy Technology Data Exchange (ETDEWEB)

    Lee, A.D.; Mayi, D.; Edgemon, S.D.

    1997-04-01

    This document presents summaries of code and utility building program evaluations reviewed as the basis for the information presented in Energy-Efficient Buildings Program Evaluations, Volume 1: Findings and Recommendations, DOE/EE/OBT-11569, Vol. 1. The main purpose of this volume is to summarize information from prior evaluations of similar programs that may be useful background for designing and conducting an evaluation of the BSGP. Another purpose is to summarize an extensive set of relevant evaluations and provide a resource for program designers, mangers, and evaluators.

  18. Progress in passive solar energy systems. Volume 8. Part 1

    Energy Technology Data Exchange (ETDEWEB)

    Hayes, J.; Andrejko, D.A.

    1983-01-01

    This book presents the papers given at a conference sponsored by the US DOE, the Solar Energy Research Institute, SolarVision, Inc., and the Southern California Solar Energy Society. The topics considered at the conference included sizing solar energy systems for agricultural applications, a farm scale ethanol production plant, the EEC wind energy RandD program, the passive solar performance assessment of an earth-sheltered house, the ARCO 1 MW photovoltaic power plant, the performance of a dendritic web photovoltaic module, second generation point focused concentrators, linear fresnel lens concentrating photovoltaic collectors, photovoltaic conversion efficiency, amorphous silicon thin film solar cells, a photovoltaic system for a shopping center, photovoltaic power generation for the utility industry, spectral solar radiation, and the analysis of insolation data.

  19. Volume correction in the aging hand: role of dermal fillers

    Directory of Open Access Journals (Sweden)

    Rivkin AZ

    2016-08-01

    Full Text Available Alexander Z Rivkin David Geffen/UCLA School of Medicine Los Angeles, CA, USA Abstract: The hands, just like the face, are highly visible parts of the body. They age at a similar rate and demonstrate comparable changes with time, sun damage, and smoking. Loss of volume in the hands exposes underlying tendons, veins, and bony prominences. Rejuvenation of the hands with dermal fillers is a procedure with high patient satisfaction and relatively low risk for complications. This study will review relevant anatomy, injection technique, clinical safety, and efficacy of dermal filler volumization of the aging hand. Keywords: dermal fillers, hands, volumization, hyaluronic acid, calcium hydroxylapatite

  20. Book review: Fowler's zoo and wild animal medicine (volume 8)

    Science.gov (United States)

    Sleeman, Jonathan M.

    2014-01-01

    In the eighth volume of Fowler's Zoo and Wild Animal Medicine, the editors have returned to the original, comprehensive, taxa-based format last used in the fifth volume that was released in 2003. The book consists of 82 chapters, divided into taxonomic classes that include amphibians, reptiles, birds, and mammals, and a general topics section. The editors deliberately selected new senior authors who are expert veterinary advisors for the various taxa. This international assemblage of authors is impressive, although the book would have benefited from a greater diversity of disciplinary expertise. Synthesis of the large and expanding body of knowledge about zoo and wild animal medicine is a Sisyphean task, but one that the editors have accomplished well. The chapters were well written and are beautifully illustrated with high-quality images and generally well referenced. Much of the information is summarized in tabular format, which I found both a blessing and a curse. Tabulation of hematologic variables and anesthetic doses is helpful; however, tabulation of information regarding infectious and parasitic diseases results in a loss of detail. For example, methods of diagnosis for some diseases are omitted from some tables. The need for succinctness results in trade-offs, and statements such as “Batrachochytrium dendrobatidis … is one of the most well described pathogens of anurans” with no further information leaves readers unsated. In addition, the book does not have any chapters on fish or invertebrates, which are notable omissions given the importance of these species. Those quibbles aside, this is a must-have book for all zoo and wild animal medicine students and practitioners. However, perhaps it is time to recognize that, during the 36 years since the first volume was published, this discipline has become too large to be contained in 1 book. This is largely because of the success of this book series, and it is a nice problem to have.

  1. Measurement of absolute left ventricular volume by radionuclide angiography: a technical review

    International Nuclear Information System (INIS)

    Al-Khawaja, I.M.; Lahiri, Avijit; Raftery, E.B.; Medical Research Council, Harrow

    1988-01-01

    Absolute left ventricular volumes have important clinical implications in the evaluation of cardiac performance. Several invasive and noninvasive techniques have been reported, none of which can be considered ideal for this purpose. Contrast angiography, echocardiography and radionuclide ventriculography are open to criticism. Different radioisotopic approaches are described with emphasis on the importance of accurate separation of left ventricular activity, the selection of background activity, and the correction for photon attenuation by body tissues. Improper use of statistics and validation techniques have obscured the value of these techniques. In the absence of a 'gold standard' there should be a 'radioisotopic' left ventricular volume with established independent characteristics, repeatability and reproducibility by which new approaches can be judged. (author)

  2. Volume of the adrenal and pituitary glands in depression

    DEFF Research Database (Denmark)

    Kessing, Lars Vedel; Willer, Inge Stoel; Knorr, Ulla

    2011-01-01

    Numerous studies have shown that the hypothalamic-pituitary-adrenal (HPA) axis is hyperactive in some depressed patients. It is unclear whether such hyperactivity results in changed volumes of the adrenal glands, pituitary gland and hypothalamus. We systematically reviewed all controlled studies ...

  3. Lung volume reduction for emphysema.

    Science.gov (United States)

    Shah, Pallav L; Herth, Felix J; van Geffen, Wouter H; Deslee, Gaetan; Slebos, Dirk-Jan

    2017-02-01

    Advanced emphysema is a lung disease in which alveolar capillary units are destroyed and supporting tissue is lost. The combined effect of reduced gas exchange and changes in airway dynamics impairs expiratory airflow and leads to progressive air trapping. Pharmacological therapies have limited effects. Surgical resection of the most destroyed sections of the lung can improve pulmonary function and exercise capacity but its benefit is tempered by significant morbidity. This issue stimulated a search for novel approaches to lung volume reduction. Alternative minimally invasive approaches using bronchoscopic techniques including valves, coils, vapour thermal ablation, and sclerosant agents have been at the forefront of these developments. Insertion of endobronchial valves in selected patients could have benefits that are comparable with lung volume reduction surgery. Endobronchial coils might have a role in the treatment of patients with emphysema with severe hyperinflation and less parenchymal destruction. Use of vapour thermal energy or a sclerosant might allow focal treatment but the unpredictability of the inflammatory response limits their current use. In this Review, we aim to summarise clinical trial evidence on lung volume reduction and provide guidance on patient selection for available therapies. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. Considerations in reviewing the waste volume reduction program in a large utility

    International Nuclear Information System (INIS)

    Kohout, R.; Calzolari, L.M.

    1987-01-01

    A program is underway at Ontario Hydro to establish a desirable future scheme for central processing/volume reduction of solid radioactive Low-Level Wastes (LLW) prior to their placement into the centralized storage, and in the future into a disposal facility. The approach being investigated is to furnish the current Waste Volume Reduction Facility (WVRF) with state-of-art processes, reclassify the waste categories and segregate the wastes such that each volume reduction (VR) process is then applied where it would be most effective. The ''optimized'' approach is then compared with other, specific schemes, which basically differ in that each scheme omits one of the major VR processes, thus allowing the next most effective process to take over its role. Each scheme is assessed quantitatively from the viewpoint of cost and VR effectiveness, and qualitatively from the viewpoint of resultant waste form. The economic assessments take into consideration the long term (20 year) impact of selected VR schemes on the overall waste management cost, including construction and operation of the storage facility. This paper highlights the overall study, includes the major results, and identifies aspects that need to be addressed in the selection of a desirable combination of VR processes in absence of knowledge of future waste disposal costs

  5. Right-Turn Traffic Volume Adjustments in Traffic Signal Warrant Analysis

    Science.gov (United States)

    2015-01-01

    To accomplish this research, a comprehensive literature review of existing guidelines and findings based on national and local studies was conducted. Ultimately, guidelines for consistent application for adjusting right-turn traffic volumes were deve...

  6. Porosity, Bulk Density, and Volume Reduction During Drying: Review of Measurement Methods and Coefficient Determinations

    NARCIS (Netherlands)

    Qiu, J.; Khalloufi, S.; Martynenko, A.; Dalen, van G.; Schutyser, M.A.I.; Almeida-Rivera, C.

    2015-01-01

    Several experimental methods for measuring porosity, bulk density and volume reduction during drying of foodstuff are available. These methods include among others geometric dimension, volume displacement, mercury porosimeter, micro-CT, and NMR. However, data on their accuracy, sensitivity, and

  7. LLE review: Quarterly report, April--June 1996. Volume 67

    Energy Technology Data Exchange (ETDEWEB)

    Skeldon, M.D. [ed.

    1996-11-01

    This volume contains articles detailing several nonlinear processes associated with lasers and their use, as well as an article describing the computer control systems necessary to maintain and operate a large laser system such as the 60-beam OMEGA laser. The specific topics discussed in this issue include stimulated scattering in laser plasmas, power exchange between interacting laser beams, charged particles interacting with a laser pulse, thermal equilibration of optically excited states, an overview of the laser control system software in OMEGA, and a technique for cancellation of the nonlinear phase accumulation in short-pulse lasers.

  8. Journal of Undergraduate Research, Volume I, 2001

    Energy Technology Data Exchange (ETDEWEB)

    Faletra, P.; Beavis, W.; Franz, K.; Musick, C.; Walbridge, S.E.; Myron, H.

    2001-01-01

    This is our first volume of the Undergraduate Journal. It is an approbation of the impressive research performed by summer interns under the guidance of their dedicated mentors. The full-length publications were chosen from a pool of submissions that were reviewed by many of the excellent scientists at our National Laboratories. Most of these students will pursue careers in science, engineering and technology and, hopefully, some of this talent will remain with our labs. We have also included about 125 abstracts that survived the review process. These were submitted from all of our participating National Laboratories.

  9. Hydration and blood volume effects on human thermoregulation in the heat: Space applications

    Science.gov (United States)

    Sawka, Michael N.; Gonzalez, Richard R.; Pandolf, Kent B.

    1994-01-01

    Astronauts exposed to prolonged weightlessness will experience deconditioning, dehydration, and hypovolemia which all adversely affect thermoregulation. These thermoregulatory problems can be minimized by several countermeasures that manipulate body water and vascular volumes. USARIEM scientists have extensively studied dehydration effects and several possible countermeasures including hyperhydration, plasma and erythrocyte volume expansion. This paper reviews USARIEM research into these areas.

  10. Determining the Optimal C-130 Deployed Crew Ratio

    Science.gov (United States)

    2014-06-13

    components. The active component operates at a 1:2 (with a goal of 1:3) deploy-to- dwell while the ARC plans a 1:5 ( Stenner , 2011, pp. 5, 10). This...Rand Corporation, 2011. Rand Corporation. Intratheater Airlift Functional Solution Analysis. Santa Monica: Rand Corporation, 2011. Stenner

  11. RESIDENTIAL WOOD COMBUSTION TECHNOLOGY REVIEW - VOLUME 2. APPENDICES

    Science.gov (United States)

    The report gives results of a review of the current state-of-the-art of residential wood combustion (RWC). The key environmental parameter of concern was the air emission of particles. The technological status of all major RWC categories--cordwood stoves, fireplaces, masonry heat...

  12. Recovery of Navy distillate fuel from reclaimed product. Volume I. Technical discussion

    Energy Technology Data Exchange (ETDEWEB)

    Brinkman, D.W.; Whisman, M.L.

    1984-11-01

    In an effort to assist the Navy to better utilize its waste hydrocarbons, NIPER, with support from the US Department of Energy, is conducting research designed to ultimately develop a practical technique for converting Reclaimed Product (RP) into specification Naval Distillate Fuel (F-76). The first phase of the project was focused on reviewing the literature and available information from equipment manufacturers. The literature survey has been carefully culled for methodology applicable to the conversion of RP into diesel fuel suitable for Navy use. Based upon the results of this study, a second phase has been developed and outlined in which experiments will be performed to determine the most practical recycling technologies. It is realized that the final selection of one particular technology may be site-specific due to vast differences in RP volume and available facilities. A final phase, if funded, would involve full-scale testing of one of the recommended techniques at a refueling depot. The Phase I investigations are published in two volumes. Volume 1, Technical Discussion, includes the narrative and Appendices I and II. Appendix III, a detailed Literature Review, includes both a narrative portion and an annotated bibliography containing about 800 referenvces and abstracts. This appendix, because of its volume, has been published separately as Volume 2. 18 figures, 4 tables.

  13. Identifying Arabic-Language Materials for Children That Promote Tolerance and Critical Thinking

    Science.gov (United States)

    2011-01-01

    grateful to Julie Taylor of RAND and Regan Gurung of the University of Wisconsin Green Bay for their care- ful reviews of this report. Finally, we owe...Islam, London: Routledge and Kegan Paul. Brewer, D. J., Augustine, C. H., Zellman, G. L., Ryan G. W., Goldman C. A., Stasz, C., and Constant, L. 2007

  14. Feedback to Managers, Volume II: A Review and Comparison of Sixteen Multi-Rater Feedback Instruments.

    Science.gov (United States)

    Van Velsor, Ellen; Leslie, Jean Brittain

    "Feedback to Managers" is a two-volume report. Volume 2 compares 16 of the better feedback instruments available. The following are the instruments: (1) ACUMEN Group Feedback; (2) BENCHMARKS; (3) the Campbell Leadership Index; (4) COMPASS: the Managerial Practices Survey; (5) the Executive Success Profile; (6) Leader Behavior Analysis…

  15. Inventory of Federal energy-related environment and safety research for FY 1978. Volume 1. Executive summary

    International Nuclear Information System (INIS)

    1979-12-01

    The FY 1978 Federal Inventory is a compilation of 3225 federally funded energy-related environmental and safety reserch projects. It consists of three volumes: an executive summary providing an overview of the data (Volume I), a catalog listing each Inventory project followed by series of indexes (Volume II), and an interactive terminal guide giving instructions for on-line data retrieval (Volume III). Volume I reviews the inventory data as a whole and also within each of three major categories: biomedical and environmental research, environmental control technology research, and operational safety research

  16. HCCR TBS LOCA and ICE into small confined volume

    International Nuclear Information System (INIS)

    Jin, Hyung Gon; Ahn, Mu-Young

    2016-01-01

    KAERI has participated in the development of HCCR (Helium Cooled Ceramic Reflector) TBS (Test Blanket System) as a member of the KO TBM Team. Conceptual design review of this system had been performed in 2015 and after resolving the chits, the final approval was achieved in March 2016. This safety issue is one of the category II chits in the CDR and resolution strategy was already approved, however, safety analysis should be done until PDR (Preliminary Design Review). In this paper, model and nodalization for the accident are given and preliminary result is included. Nominal design pressure of HCS loop is 8 MPa, therefore, as indicated in the figure below. During the break of cooling pipe between TBM and Shield, the high pressure coolant will ingress to the 'interspace' between TBM, Shield and Frame. The coolant will be released through the front gaps between TBM and Frame towards VV primary vacuum. Accident analysis about HCCR TBS LOCA and ICE into small confined volume has been done successfully. Inverspace volume is compatibly small volume for 8MPa helium loop rupture, which causes fast pressure build-up the space but it decrease within 10 seconds. It is expected that other type of TBM has almost the same behavior

  17. Neoarchaean tectonic history of the Witwatersrand Basin and Ventersdorp Supergroup: New constraints from high-resolution 3D seismic reflection data

    CSIR Research Space (South Africa)

    Manzi, MSD

    2013-04-01

    Full Text Available Rand Group (ca. 2985–2902 Ma) is unconformably overlain by the Central Rand Group (ca. 2902–2849 Ma), with tilting of the West Rand Group syn- to post-erosion at ca. 2.9 Ga. The seismic sections also confirm that an unconformable relationship exists...

  18. Health Sector Reform in the Kurdistan Region - Iraq: Financing Reform, Primary Care, and Patient Safety.

    Science.gov (United States)

    Anthony, C Ross; Moore, Melinda; Hilborne, Lee H; Mulcahy, Andrew W

    2014-12-30

    In 2010, the Kurdistan Regional Government asked the RAND Corporation to help guide reform of the health care system in the Kurdistan Region of Iraq. The overarching goal of reform was to help establish a health system that would provide high-quality services efficiently to everyone to prevent, treat, and manage physical and mental illnesses and injuries. This article summarizes the second phase of RAND's work, when researchers analyzed three distinct but intertwined health policy issue areas: development of financing policy, implementation of early primary care recommendations, and evaluation of quality and patient safety. For health financing, the researchers reviewed the relevant literature, explored the issue in discussions with key stakeholders, developed and assessed various policy options, and developed plans or approaches to overcome barriers and achieve stated policy objectives. In the area of primary care, they developed and helped to implement a new management information system. In the area of quality and patient safety, they reviewed relevant literature, discussed issues and options with health leaders, and recommended an approach toward incremental implementation.

  19. Review of Department of Defense Education Activity (DODEA) Schools. Volume II: Quantitative Analysis of Educational Quality

    National Research Council Canada - National Science Library

    Anderson, Lowell

    2000-01-01

    This volume compiles, and presents in integrated form, IDA's quantitative analysis of educational quality provided by DoD's dependent schools, It covers the quantitative aspects of volume I in greater...

  20. The order and volume fill rates in inventory control systems

    DEFF Research Database (Denmark)

    Thorstenson, Anders; Larsen, Christian

    2014-01-01

    This paper differentiates between an order (line) fill rate and a volume fill rate and specifies their performance for different inventory control systems. When the focus is on filling complete customer orders rather than total demanded quantity the order fill rate would be the preferred service...... level measure. The main result shows how the order and volume fill rates are related in magnitude. Earlier results derived for a single-item, single-stage, continuous review inventory system with backordering and constant lead times controlled by a base-stock policy are extended in different directions...... extensions consider more general inventory control review policies with backordering, as well as some relations between service measures. A particularly important result in the paper concerns an alternative service measure, the customer order fill rate, and shows how this measure always exceeds the other two...

  1. Proceedings of the coal-fired power systems 94: Advances in IGCC and PFBC review meeting. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    McDaniel, H.M.; Staubly, R.K.; Venkataraman, V.K. [eds.

    1994-06-01

    The Coal-Fired Power Systems 94 -- Advances in IGCC and PFBC Review Meeting was held June 21--23, 1994, at the Morgantown Energy Center (METC) in Morgantown, West Virginia. This Meeting was sponsored and hosted by METC, the Office of Fossil Energy, and the US Department of Energy (DOE). METC annually sponsors this conference for energy executives, engineers, scientists, and other interested parties to review the results of research and development projects; to discuss the status of advanced coal-fired power systems and future plans with the industrial contractors; and to discuss cooperative industrial-government research opportunities with METC`s in-house engineers and scientists. Presentations included industrial contractor and METC in-house technology developments related to the production of power via coal-fired Integrated Gasification Combined Cycle (IGCC) and Pressurized Fluidized Bed Combustion (PFBC) systems, the summary status of clean coal technologies, and developments and advancements in advanced technology subsystems, such as hot gas cleanup. A keynote speaker and other representatives from the electric power industry also gave their assessment of advanced power systems. This meeting contained 11 formal sessions and one poster session, and included 52 presentations and 24 poster presentations. Volume I contains papers presented at the following sessions: opening commentaries; changes in the market and technology drivers; advanced IGCC systems; advanced PFBC systems; advanced filter systems; desulfurization system; turbine systems; and poster session. Selected papers have been processed separately for inclusion in the Energy Science and Technology Database.

  2. Anomaly-free perturbations with inverse-volume and holonomy corrections in loop quantum cosmology

    International Nuclear Information System (INIS)

    Cailleteau, Thomas; Linsefors, Linda; Barrau, Aurelien

    2014-01-01

    This paper addresses the issue of the closure of the algebra of constraints for generic (cosmological) perturbations when taking into account simultaneously the two main corrections of effective loop quantum cosmology, namely the holonomy and the inverse-volume terms. Previous works on either the holonomy or the inverse-volume case are reviewed and generalized. In the inverse-volume case, we point out new possibilities. An anomaly-free solution including both corrections is found for perturbations, and the corresponding equations of motion are derived. (paper)

  3. Left ventricular volume during supine exercise: importance of myocardial scar in patients with coronary heart disease

    International Nuclear Information System (INIS)

    Mann, D.L.; Scharf, J.; Ahnve, S.; Gilpin, E.

    1987-01-01

    Existing studies suggest that exercise-induced ischemia produces an increase in left ventricular end-diastolic volume; however, all of these studies have included patients with previous myocardial infarction. To test whether the end-diastolic volume response to exercise is related to the extent of myocardial scar, the results of gated radionuclide supine exercise tests performed on 130 subjects were reviewed. The patient group comprised 130 subjects were reviewed. The patient group comprised 130 men aged 35 to 65 years (mean +/- SD 52 +/- 5) with documented coronary heart disease. The extent of myocardial ischemia and scar formation was assessed by stress electrocardiography and thallium-201 scintigraphy. Patients were classified into three groups on the basis of left ventricular end-diastolic volume response at peak exercise: group 1 (n = 72) had an increase of end-diastolic volume greater than 10%, group 2 (n = 41) had a change in end-diastolic volume less than 10% and group 3 (n = 17) had a decrease in end-diastolic volume greater than 10% (n = 17). At rest there was no significant difference among groups in heart rate, systolic blood pressure, end-diastolic (EDVrest) or end-systolic volumes or ejection fraction (p greater than 0.05); however, at peak exercise the end-systolic volume response was significantly greater for group 1 (p less than 0.002)

  4. Histamine iontophoresis on the viability of random skin flap in rats Iontoforese de histamina na viabilidade do retalho cutâneo randômico em ratos

    Directory of Open Access Journals (Sweden)

    Ivaldo Esteves Júnior

    2009-02-01

    Full Text Available PURPOSE: To evaluate the effects of the histamine iontophoresis on the random skin flap viability in rats. METHODS: Sixty adult male Wistar rats were used. A cranially-based dorsal skin flap measuring 10 x 4 cm was raised and a plastic barrier was placed between the flap and its bed. After the surgical procedure, the animals were randomized into four groups (G1-G4 (n=15 each group as follows: G1 (control - sham electrical stimulation, G2 (electrical stimulation - direct current electrical stimulation, G3 (histamine - histamine and sham electrical stimulation and G4 (histamine iontophoresis - transdermal iontophoresis of histamine. In all groups the procedures were performed immediately after the surgery and on the two subsequent days. The percentage of flap necrosis was measured on the seventh postoperative day. RESULTS: The mean and the respective standard deviation of the percentage of flap necrosis areas were as follows: G1 (control - 47.87 ± 9.13%, G2 - 51.49 ± 8.19%, G3 - 46.33 ± 8.32% and G4 - 30.82 ± 11.25%. The G4 group presented a significantly smaller amount of flap necrosis when compared to the other groups (pOBJETIVO: Avaliar o efeito da iontoforese de histamina na viabilidade do retalho cutâneo randômico em ratos. MÉTODOS: Foram utilizados 60 ratos adultos e machos da linhagem Wistar. O retalho cutâneo de base cranial, medindo 10x4 cm, foi elevado no dorso dos animais e uma barreira plástica foi interposta entre o retalho e a área doadora. Após o procedimento operatório, os animais foram distribuídos aleatoriamente em 4 grupos (G1-G4 (n=15 em cada grupo a saber: G1 (controle - simulação da estimulação elétrica, G2 (estimulação elétrica - estimulação elétrica com corrente direta, G3 (histamina - histamina e simulação da estimulação elétrica e G4 (iontoforese de histamina - iontoforese transdérmica de histamina. Em todos os grupos os procedimentos foram realizados imediatamente após a operação e nos 2

  5. Psychological Fitness and Resilience: A Review of Relevant Constructs, Measures, and Links to Well-Being

    Science.gov (United States)

    2014-01-01

    and Doctrine. Additional information about PAF is available on our website: http://www.rand.org/paf/ v Contents Preface...through seeking help, rumination , problem solving, denial, or cognitive restructuring” (Skinner et al. , 2003, p. 216). A vast literature has been...reflection, which involves “self-attentiveness motivated by curiosity . . . in the self” and (2) rumination , which involves “self-attentiveness

  6. Annual review of materials science. Volume 7

    International Nuclear Information System (INIS)

    Huggins, R.A.; Bube, R.H.; Roberts, R.W.

    1977-01-01

    A review is presented of recent materials science research. Topics covered include: point defects and their interaction; defect chemistry in crystalline solids; deep level impurities in semiconductors; structural aspects of one-dimensional conductors; structural transformations during aging of metal alloys; high rate thick film growth; metal forming, the application of limit analysis; kinetics and mechanisms of gas-metal interactions; erosion; reversible temper embrittlement; acoustic emission in brittle materials; capacitance transient spectroscopy; hot corrosion of high-temperature alloys; fundamental optical phenomena in infrared window materials; dental amalgam; and transparent conducting coatings

  7. Shared Communications: Volume 2. In-Depth Systems Research

    Energy Technology Data Exchange (ETDEWEB)

    Truett, LF

    2004-09-22

    This report is the second of two documents that examine the literature for actual examples of organizations and agencies that share communications resources. While the primary emphasis is on rural, intelligent transportation system (ITS) communications involving transit, examples will not be limited to rural activities, nor to ITS implementation, nor even to transit. In addition, the term ''communication'' will be broadly applied to include all information resources. The first document of this series, ''Shared Communications: Volume I. A Summary and Literature Review'', defines the meaning of the term ''shared communication resources'' and provides many examples of agencies that share resources. This document, ''Shared Communications: Volume II. In-Depth Systems Research'', reviews attributes that contributed to successful applications of the sharing communication resources concept. A few examples of each type of communication sharing are provided. Based on the issues and best practice realworld examples, recommendations for potential usage and recommended approaches for field operational tests are provided.

  8. Gray Matter Volumes in Patients with Chronic Fatigue Syndrome

    Directory of Open Access Journals (Sweden)

    Le-wei Tang

    2015-01-01

    Full Text Available Chronic fatigue syndrome (CFS is a debilitating and complex disorder characterized by profound fatigue with uncertain pathologic mechanism. Neuroimage may be an important key to unveil the central nervous system (CNS mechanism in CFS. Although most of the studies found gray matter (GM volumes reduced in some brain regions in CFS, there are many factors that could affect GM volumes in CFS, including chronic pain, stress, psychiatric disorder, physical activity, and insomnia, which may bias the results. In this paper, through reviewing recent literatures, we discussed these interferential factors, which overlap with the symptoms of CFS.

  9. Resenha de: Business History Review

    Directory of Open Access Journals (Sweden)

    José Sebastião Witter

    1966-09-01

    Full Text Available BUSINESS HISTORY REVIEW. — Published quaterly by The Harvard Graduate School of Business Administration. Volume XXXIX, number 4. Winter 1965. Soldiers Field, Boston, Massachussets.

  10. Reviews in fluorescence 2007

    CERN Document Server

    Lakowicz, Joseph R; Geddes, Chris D

    2009-01-01

    This fourth volume in the Springer series summarizes the year's progress in fluorescence, with authoritative analytical reviews specialized enough for professional researchers, yet also appealing to a wider audience of scientists in related fields.

  11. Lung volume recruitment in multiple sclerosis.

    Directory of Open Access Journals (Sweden)

    Nadim Srour

    Full Text Available INTRODUCTION: Pulmonary function abnormalities have been described in multiple sclerosis including reductions in forced vital capacity (FVC and cough but the time course of this impairment is unknown. Peak cough flow (PCF is an important parameter for patients with respiratory muscle weakness and a reduced PCF has a direct impact on airway clearance and may therefore increase the risk of respiratory tract infections. Lung volume recruitment is a technique that improves PCF by inflating the lungs to their maximal insufflation capacity. OBJECTIVES: Our goals were to describe the rate of decline of pulmonary function and PCF in patients with multiple sclerosis and describe the use of lung volume recruitment in this population. METHODS: We reviewed all patients with multiple sclerosis referred to a respiratory neuromuscular rehabilitation clinic from February 1999 until December 2010. Lung volume recruitment was attempted in patients with FVC <80% predicted. Regular twice daily lung volume recruitment was prescribed if it resulted in a significant improvement in the laboratory. RESULTS: There were 79 patients included, 35 of whom were seen more than once. A baseline FVC <80% predicted was present in 82% of patients and 80% of patients had a PCF insufficient for airway clearance. There was a significant decline in FVC (122.6 mL/y, 95% CI 54.9-190.3 and PCF (192 mL/s/y, 95% 72-311 over a median follow-up time of 13.4 months. Lung volume recruitment was associated with a slower decline in FVC (p<0.0001 and PCF (p = 0.042. CONCLUSION: Pulmonary function and cough decline significantly over time in selected patients with multiple sclerosis and lung volume recruitment is associated with a slower rate of decline in lung function and peak cough flow. Given design limitations, additional studies are needed to assess the role of lung volume recruitment in patients with multiple sclerosis.

  12. Military Review, July 1992. Volume 72, Number 7

    Science.gov (United States)

    1992-07-01

    Williamrs Assistant Secretary of Defense tor Pubic 47 Alexander Hamilton. The Federalist Papers (New York: NAIL Penguin Inc. Affairs before the...REVIEW THE OMG /~’TA Im Figurer 141 h a t fta 0 wor m TE (~YV7 Figur 2A Army can continue defending, withdraw or "Missions for the army plan include the

  13. The order and volume fill rates in inventory control systems

    DEFF Research Database (Denmark)

    Thorstenson, Anders; Larsen, Christian

    2011-01-01

    This paper differentiates between an order (line) fill rate and a volume fill rate and specifies their performance for different inventory control systems. When the focus is on filling complete customer orders rather than total quantities the order fill rate would be the preferred service level...... measure. The main result shows how the order and volume fill rates are related in magnitude. Earlier results derived for a single-item, single-stage, continuous review inventory system with backordering and constant lead times controlled by a base-stock policy are extended in different directions...

  14. Reviews in fluorescence 2010

    CERN Document Server

    Geddes, Chris D

    2011-01-01

    ""Reviews in Fluorescence 2010"", the seventh volume of the book serial from Springer, serves as a comprehensive collection of current trends and emerging hot topics in the field of fluorescence and closely related disciplines. It summarizes the year's progress in fluorescence and its applications, with authoritative analytical reviews specialized enough to be attractive to professional researchers, yet also appealing to the wider audience of scientists in related disciplines of fluorescence. ""Reviews in Fluorescence"" offers an essential reference material for any lab working in the fluoresc

  15. The Role of Logic Modeling in a Collaborative and Iterative Research Process: Lessons from Research and Analysis Conducted with the Federal Voting Assistance Program

    Science.gov (United States)

    2016-01-01

    NIOSH, 2009. As of July 21, 2015: http://www.rand.org/pubs/monographs/MG809.html W. K. Kellogg Foundation, Logic Model Development Guide, Battle...RAND Corporation, MG-809-NIOSH, 2009. As of July 21, 2015: http://www.rand.org/pubs/monographs/MG809.html W. K. Kellogg Foundation, Logic Model

  16. Technical evaluation of Aerojet Energy Conversion Company's topical report on a mobile volume reduction system

    International Nuclear Information System (INIS)

    Henscheid, J.W.

    1984-01-01

    This report summarizes EG and G Idaho's review of Aerojet Energy Conversion Company's (AECC's) topical report on a Mobile Volume Reduction System. The review evaluated compliance with pertinent codes, standards and regulations. The initial review was discussed with AECC by EG and G Idaho and the NRC, and all outstanding issues resolved before this final evaluation was made

  17. Baixa prevalência de discromatopsia, pela 4ª edição do teste pseudoisocromático HRR (Hardy, Rand e Rittler), da população indígena de etnia terena da aldeia lalima na região de Miranda: Mato Grosso do Sul

    OpenAIRE

    Piccinin,Marcos Rogério Mistro; Cunha,Juliana Ferrari; Almeida,Herbert Paulo de; Bach,Cleiton Cassio; Dossa,Andréa Cristina Grubits Gonçalves de Oliveira; Silva,Reinaldo Ferreira da; Pessoa,Valdir Filgueiras

    2007-01-01

    OBJETIVO: Avaliar a freqüência de discromatopsias através da 4ª edição do teste pseudoisocromático HRR (Hardy, Rand and Rittler) entre a população indígena masculina da aldeia Lalima, etnia Terena, na região de Miranda-MS. MÉTODOS: Foram realizadas viagens à aldeia Lalima em Miranda-MS, nos meses de janeiro e fevereiro de 2005. As viagens para realizar os exames só foram iniciadas após o projeto ter sido avaliado e aprovado pelos Comitê de Ética e Pesquisa da UFMS, Comitê Nacional de Ética e ...

  18. Book review

    African Journals Online (AJOL)

    The work under review is Jack Mapanje's third volume of verse after Of Chameleons ... with which the new book opens, 'The Following Dawn the Boots', talks about the first ... 'St Margaret Chitherow of York', the poet acknowledges that his host country too has ... primary audience and learn to adjust his sights accordingly.

  19. Annual review of energy. Volume 6

    Science.gov (United States)

    Hollander, J. M.; Simmons, M. K.; Wood, D. O.

    Developments in the areas of energy resources and supply technologies, energy end use and conservation, energy policy, energy-related risks and the sociopolitical aspects of energy are reviewed. Progress in solar energy technologies over the last five years is discussed, along with the implications for reactor safety of the accident at Three Mile Island, the derivation of biomass fuels from agricultural products and the application of probabilistic risk assessment to energy technologies. Attention is also given to a program for national survival during an oil crisis, energy conservation in new buildings, the development of a United States synthetic fuel industry, the role of OPEC policies in world oil availability, the social impacts of soft and hard energy systems, and the energy implications of fixed rail mass transportation systems. Additional topics include the energy consumptions of industries, the relative economics of nuclear, coal and oil-fired electricity generation, and the role of petroleum price and allocation regulations in the management of energy shortages.

  20. Activation of ion transport systems during cell volume regulation

    International Nuclear Information System (INIS)

    Eveloff, J.L.; Warnock, D.G.

    1987-01-01

    This review discusses the activation of transport pathways during volume regulation, including their characteristics, the possible biochemical pathways that may mediate the activation of transport pathways, and the relations between volume regulation and transepithelial transport in renal cells. Many cells regulate their volume when exposed to an anisotonic medium. The changes in cell volume are caused by activation of ion transport pathways, plus the accompanying osmotically driven water movement such that cell volume returns toward normal levels. The swelling of hypertonically shrunken cells is termed regulatory volume increase (RVI) and involves an influx of NaCl into the cell via either activation of Na-Cl, Na-K-2Cl cotransport systems, or Na + -H + and Cl - -HCO 3 - exchangers. The reshrinking of hypotonically swollen cells is termed regulatory volume decrease (RVD) and involves an efflux of KCl and water from the cell by activation of either separate K + and Cl - conductances, a K-Cl cotransport system, or parallel K + -H + and Cl - -HCO 3 - exchangers. The biochemical mechanisms involved in the activation of transport systems are largely unknown, however, the phosphoinositide pathway may be implicated in RVI; phorbol esters, cGMP, and Ca 2+ affect the process of volume regulation. Renal tubular cells, as well as the blood cells that transverse the medulla, are subjected to increasing osmotic gradients from the corticomedullary junction to the papillary tip, as well as changing interstitial and tubule fluid osmolarity, depending on the diuretic state of the animal. Medullary cells from the loop of Henle and the papilla can volume regulate by activating Na-K-2Cl cotransport or Na + -H + and Cl - -HCO 3 - exchange systems

  1. Making an Impact in the Kurdistan Region--Iraq. Summary of Four Studies to Assess the Present and Future Labor Market, Improve Technical Vocational Education and Training, Reform the Health Sector, and Build Data Collection Capacity. Research Report

    Science.gov (United States)

    Anthony, C. Ross; Constant, Louay; Culbertson, Shelby; Click, Peter; Kumar, Krishna B.; Meili, Robin C.; Moore, Melinda; Shatz, Howard J.; Vernez, Georges

    2015-01-01

    This executive summary describes key results from four studies carried out by the RAND Corporation as part of Phase II of its work for the Kurdistan Regional Government (KRG). The KRG asked RAND to undertake several studies aimed at improving the economic and social development of the Kurdistan Region--Iraq (KRI). RAND's work is intended to help…

  2. Tidal volume and mortality in mechanically ventilated children: a systematic review and meta-analysis of observational studies*.

    Science.gov (United States)

    de Jager, Pauline; Burgerhof, Johannes G M; van Heerde, Marc; Albers, Marcel J I J; Markhorst, Dick G; Kneyber, Martin C J

    2014-12-01

    To determine whether tidal volume is associated with mortality in critically ill, mechanically ventilated children. MEDLINE, EMBASE, and CINAHL databases from inception until July 2013 and bibliographies of included studies without language restrictions. Randomized clinical trials and observational studies reporting mortality in mechanically ventilated PICU patients. Two authors independently selected studies and extracted data on study methodology, quality, and patient outcomes. Meta-analyses were performed using the Mantel-Haenszel random-effects model. Heterogeneity was quantified using I. Study quality was assessed using the Newcastle-Ottawa Score for cohort studies. Out of 142 citations, seven studies met the inclusion criteria, and additional two articles were identified from references of the found articles. One was excluded. These eight studies included 1,756 patients. Mortality rates ranged from 13% to 42%. There was no association between tidal volume and mortality when tidal volume was dichotomized at 7, 8, 10, or 12 mL/kg. Comparing patients ventilated with tidal volume less than 7 mL/kg and greater than 10 mL/kg or greater than 12 mL/kg and tidal volume less than 8 mL/kg and greater than 10 mL/kg or greater than 12 mL/kg also showed no association between tidal volume and mortality. Limiting the analysis to patients with acute lung injury/acute respiratory distress syndrome did not change these results. Heterogeneity was observed in all pooled analyses. A relationship between tidal volume and mortality in mechanically ventilated children could not be identified, irrespective of the severity of disease. The significant heterogeneity observed in the pooled analyses necessitates future studies in well-defined patient populations to understand the effects of tidal volume on patient outcome.

  3. Reducing the volume, exposure and negative impacts of advertising for foods high in fat, sugar and salt to children: a systematic review of the evidence from statutory and self-regulatory actions and educational measures

    OpenAIRE

    Chambers, Stephanie; Freeman, Ruth; Anderson, Annie S.; MacGillivray, Steve

    2015-01-01

    Purpose:\\ud To identify and review evidence on 1) the effectiveness of statutory and self-regulatory actions to reduce the volume, exposure or wider impact of advertising for foods high in fat, sugar and salt (HFSS) to children, and 2) the role of educational measures.\\ud Design/methodology/approach:\\ud A systematic review of three databases (Medline, CINAHL and PsycINFO) and grey literature was carried out. Relevant evidence included studies evaluating advertising bans and restrictions, adve...

  4. Reviews in fluorescence 2008

    CERN Document Server

    Geddes, Chris D

    2010-01-01

    This volume serves as a comprehensive collection of current trends and emerging hot topics in the field of fluorescence spectroscopy. It summarizes the year's progress in fluorescence and its applications as well as includes authoritative analytical reviews.

  5. Reviews in plasmonics 2010

    CERN Document Server

    Geddes, Chris D

    2011-01-01

    Reviews in Plasmonics 2010, the first volume of the new book serial from Springer, serves as a comprehensive collection of current trends and emerging hot topics in the field of Plasmonics and closely related disciplines. It summarizes the year's progress in surface plasmon phenomena and its applications, with authoritative analytical reviews specialized enough to be attractive to professional researchers, yet also appealing to the wider audience of scientists in related disciplines of Plasmonics. Reviews in Plasmonics offers an essential reference material for any lab working in the Plasmonic

  6. Do high-volume hospitals and surgeons provide better care in urologic oncology?

    Science.gov (United States)

    Eastham, James A

    2009-01-01

    Studies focusing primarily on hospital or surgical volume as a surrogate for surgical experience have found substantial variations in outcomes. Increasing surgical experience has been shown to improve outcomes after multiple procedures, including esophagectomy, pancreatectomy, and primary surgery for colon and breast cancer. More recently, evidence has been presented that surgical volume/experience affects quality of life and cancer control outcomes after urologic oncology procedures. Although most of these data pertain to radical prostatectomy, similar conclusions have been reached for radical cystectomy, retroperitoneal lymph node dissection, and management of renal cell carcinoma. This review highlights data indicating that high-volume surgeons and hospitals provide better care for radical prostatectomy.

  7. DECOMPOSITION OF MANUFACTURING PROCESSES: A REVIEW

    Directory of Open Access Journals (Sweden)

    N.M.Z.N. Mohamed

    2012-06-01

    Full Text Available Manufacturing is a global activity that started during the industrial revolution in the late 19th century to cater for the large-scale production of products. Since then, manufacturing has changed tremendously through the innovations of technology, processes, materials, communication and transportation. The major challenge facing manufacturing is to produce more products using less material, less energy and less involvement of labour. To face these challenges, manufacturing companies must have a strategy and competitive priority in order for them to compete in a dynamic market. A review of the literature on the decomposition of manufacturing processes outlines three main processes, namely: high volume, medium volume and low volume. The decomposition shows that each sub process has its own characteristics and depends on the nature of the firm’s business. Two extreme processes are continuous line production (fast extreme and project shop (slow extreme. Other processes are in between these two extremes of the manufacturing spectrum. Process flow patterns become less complex with cellular, line and continuous flow compared with jobbing and project. The review also indicates that when the product is high variety and low volume, project or functional production is applied.

  8. Risk factors influencing the pleural drainage volume after transthoracic oesophagectomy.

    Science.gov (United States)

    Kosugi, Shin-ichi; Kanda, Tatsuo; Yajima, Kazuhito; Ishikawa, Takashi; Sakamoto, Kaoru

    2013-06-01

    The objective of this study was to clarify the factors influencing pleural drainage volume after transthoracic oesophagectomy and to determine criteria for the selection of patients who would benefit from the early removal of chest drains. Clinicopathological characteristics of 155 patients who underwent transthoracic oesophagectomy were prospectively collected, and the daily drainage volume of each patient was retrospectively reviewed. Potential risk factors were compared between the high-output group (n = 39) and low-output group (n = 116), which were dichotomized using the 75th percentile of total pleural drainage volume of the total study population. Multivariate logistic regression analyses were used to identify independent risk factors. The median duration of drainage was 10 days, with a median total drainage volume of 2258 ml. Of 27 potential risk factors influencing the drainage volume, creatinine clearance (P = 0.04), operative approach (P = 0.03) and thoracic duct removal (P = 0.01) were significantly associated with the total pleural drainage volume. The removal of the thoracic duct (P = 0.02; odds ratio, 4.02; 95% confidence interval 1.20-13.41) and lower creatinine clearance (P = 0.04; odds ratio, 1.02; 95% confidence interval 1.00-1.04) was independent risk factors for increased pleural drainage volume after transthoracic oesophagectomy. The early removal of chest drains may be possible in patients without these risk factors.

  9. Reducing the volume, exposure and negative impacts of advertising for foods high in fat, sugar and salt to children: A systematic review of the evidence from statutory and self-regulatory actions and educational measures.

    Science.gov (United States)

    Chambers, Stephanie A; Freeman, Ruth; Anderson, Annie S; MacGillivray, Steve

    2015-06-01

    To identify and review evidence on 1) the effectiveness of statutory and self-regulatory actions to reduce the volume, exposure or wider impact of advertising for foods high in fat, sugar and salt (HFSS) to children, and 2) the role of educational measures. A systematic review of three databases (Medline, CINAHL and PsycINFO) and grey literature was carried out. Relevant evidence included studies evaluating advertising bans and restrictions, advertising literacy programmes and parental communication styles. Relevant media included TV, internet, radio, magazines and newspaper advertising. No studies were excluded based on language or publication date. Forty-seven publications were included: 19 provided evidence for the results of statutory regulation, 25 for self-regulation, and six for educational approaches. Outcome measures varied in approach, quality and results. Findings suggested statutory regulation could reduce the volume of and children's exposure to advertising for foods HFSS, and had potential to impact more widely. Self-regulatory approaches showed varied results in reducing children's exposure. There was some limited support for educational measures. Consistency in measures from evaluations over time would assist the development and interpretation of the evidence base on successful actions and measures to reduce the volume, exposure and impact of advertising for foods HFSS to children. Copyright © 2015 Elsevier Inc. All rights reserved.

  10. Book review

    Directory of Open Access Journals (Sweden)

    EC Thomas

    1978-11-01

    Full Text Available This book appears to the present reviewer to be, if not the, at least a definitive volume for students of work motivation, whether organizational behaviourists or practising managers. This field has grown rapidly as the main focus of Organizational Psychology since Vroom's (1964 enunciation of a tenable theory of work motivation and satisfaction.

  11. Diversion path analysis handbook. Volume 2 (of 4 volumes). Example

    International Nuclear Information System (INIS)

    Goodwin, K.E.; Schleter, J.C.; Maltese, M.D.K.

    1978-11-01

    Volume 2 of the Handbook is divided into two parts, the workpaper documentation and the summary documentation. The former sets forth, in terms of the hypothetical process, the analysis guidelines, the information gathered, the characterization of the process, the specific diversion paths related to the process, and, finally, the results and findings of the Diversion Path Analysis (DPA). The summary documentation, made up of portions of sections already prepared for the workpapers, is a concise statement of results and recommendations for management use. Most of the details available in the workpapers are not used, or are held to a minimum, in this report. Also, some rearrangement of the excerpted sections has been made in order to permit rapid comprehension by a manager having only limited time to devote to study and review of the analysis

  12. Shared Communications: Volume 1. A Summary and Literature Review

    Energy Technology Data Exchange (ETDEWEB)

    Franzese, O

    2004-09-22

    This paper provides a review of examples from the literature of shared communication resources and of agencies and/or organizations that share communication resources. The primary emphasis is on rural, intelligent transportation system communications involving transit. Citations will not be limited, however, to rural activities, or to ITS implementation, or even to transit. In addition, the term ''communication'' will be broadly applied to include all information resources. Literature references to issues that contribute to both successful and failed efforts at sharing communication resources are reviewed. The findings of this literature review indicate that: (1) The most frequently shared communication resources are information/data resources, (2) Telecommunications infrastructure and technologies are the next most frequently shared resources, (3) When resources are successfully shared, all parties benefit, (4) A few unsuccessful attempts of sharing resources have been recorded, along with lessons learned, (5) Impediments to sharing include security issues, concerns over system availability and reliability, service quality and performance, and institutional barriers, (6) Advantages of sharing include financial benefits to agencies from using shared resources and benefits to the public in terms of congestion mitigation, information transfer (e.g., traveler information systems), mobility (e.g., welfare-to-work paratransit), and safety (e.g., speed of incident response, incident avoidance), (7) Technology-based solutions exist to address technology-based concerns, and (8) Institutional issues can be addressed through leadership, enhanced knowledge and skills, open communication, responsiveness, and attractive pricing structures.

  13. Do Joint Fighter Programs Save Money?

    Science.gov (United States)

    2013-01-01

    Reports & Bookstore Make a charitable contribution Limited Electronic Distribution Rights This document and trademark(s) contained herein are protected by...reflect the opinions of its research clients and sponsors. Support RAND—make a tax-deductible charitable contribution at www.rand.org/giving...Ahn, Sanghoon, Competition, Innovation and Productivity Growth: A Review of Theory and Evidence, Paris: Organisation for Economic Co-Operation and

  14. A Report to the President: Analytic Perspectives on the Science and Technology Issues Facing the Nation

    Science.gov (United States)

    2001-01-01

    Initiatives CAROLINE WAGNER Research Planning and OSTP Coordination LISA SHELDONE Research Administration and Financial Management DAVID ADAMSON...Communications LISA NEUFELD Contract Administration and Financial Management REVIEWS FROM S&T POLICY INSTITUTE PROJECT SPONSORS “The Science & Technology Policy...NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Science and Technology Policy Instituite , RAND, 1200 South Hayes St

  15. Change in Seroma Volume During Whole-Breast Radiation Therapy

    International Nuclear Information System (INIS)

    Sharma, Rajiv; Spierer, Marnee; Mutyala, Subhakar; Thawani, Nitika; Cohen, Hillel W.; Hong, Linda; Garg, Madhur K.; Kalnicki, Shalom

    2009-01-01

    Purpose: After breast-conserving surgery, a seroma often forms in the surgical cavity. If not drained, it may affect the volume of tumor bed requiring a boost after whole-breast radiation therapy (WBRT). Our objective was to evaluate the change in seroma volume that occurs during WBRT, before boost planning. Methods and Materials: A retrospective review was performed of women receiving breast-conserving therapy with evidence of seroma at the time of WBRT planning. Computed tomography (CT) simulation was performed before WBRT and before the tumor bed boost. All patients received either a hypofractionated (42.4 Gy/16 fraction + 9.6 Gy/4 fraction boost) or standard fractionated (50.4 Gy/28 fraction + 10 Gy/5 fraction boost) regimen. Seroma volumes were contoured and compared on CT at the time of WBRT simulation and tumor bed boost planning. Results: Twenty-four patients with evidence of seroma were identified and all patients received WBRT without drainage of the seroma. Mean seroma volume before WBRT and at boost planning were significantly different at 65.7 cm 3 (SD, 50.5 cm 3 ) and 35.6 cm 3 (SD, 24.8 cm 3 ), respectively (p < 0.001). Mean and median reduction in seroma volume during radiation were 39.6% (SD, 23.8%) and 46.2% (range, 10.7-76.7%), respectively. Fractionation schedule was not correlated with change in seroma volume. Length of time from surgery to start of radiation therapy showed an inverse correlation with change in seroma volume (Pearson correlation r = -0.53, p < 0.01). Conclusions: The volume of seroma changes significantly during WBRT. Consequently, the accuracy of breast boost planning is likely affected, as is the volume of normal breast tissue irradiated. CT-based boost planning before boost irradiation is suggested to ensure appropriate coverage.

  16. Ion channels involved in cell volume regulation: effects on migration, proliferation, and programmed cell death in non adherent EAT cells and adherent ELA cells.

    Science.gov (United States)

    Hoffmann, Else Kay

    2011-01-01

    This mini review outlines studies of cell volume regulation in two closely related mammalian cell lines: nonadherent Ehrlich ascites tumour cells (EATC) and adherent Ehrlich Lettre ascites (ELA) cells. Focus is on the regulatory volume decrease (RVD) that occurs after cell swelling, the volume regulatory ion channels involved, and the mechanisms (cellular signalling pathways) that regulate these channels. Finally, I shall also briefly review current investigations in these two cell lines that focuses on how changes in cell volume can regulate cell functions such as cell migration, proliferation, and programmed cell death. Copyright © 2011 S. Karger AG, Basel.

  17. Endoscopic stenting in bile duct cancer increases liver volume.

    Science.gov (United States)

    Lee, Chang Hun; Kim, Seong Hun; Kim, In Hee; Kim, Sang Wook; Lee, Soo Teik; Kim, Dae Ghon; Yang, Jae Do; Yu, Hee Chul; Cho, Baik Hwan; Lee, Seung Ok

    2014-09-01

    Objective evaluation tools for assessing the effectiveness of stenting in palliative treatment of malignant biliary obstruction are not satisfactory. Effects of biliary stenting on liver volume change have never been studied. We aimed to use volumetry to analyze liver volume changes after endoscopic stenting in bile duct cancer according to the location and number of stents. Retrospective review. University hospital. Patients with a diagnosis of hilar or distal bile duct cancer and who underwent biliary metal stenting. ERCP with self-expandable metal stent placement. Liver volume change after biliary stenting and its comparison according to the location (hilar vs distal common bile duct) and number (hilar bilateral vs hilar unilateral). There were 60 patients; 31 were treated for hilar bile duct cancer (13 for bilateral stent and 18 for unilateral stent) and 29 for distal bile duct cancer. Overall mean follow-up duration was 11.7 ± 4.9 weeks. Liver volume increased 17.4 ± 24.1%. The rate of liver growth was rapid during the early period from 4 to 8 weeks. Stenting in hilar bile duct cancer tended to increase liver volume more than distal biliary stents (22.5% vs 11.9%, P = .091). In hilar bile duct cancer, unilateral and bilateral stents showed similar liver volume increases (20.1% and 25.8%, respectively; P = .512). Single center, retrospective. Biliary stenting markedly increased liver volume in both hilar and distal bile duct cancer. Our data suggest that liver volume assessment could be a useful tool for evaluating stent efficacy. Copyright © 2014 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.

  18. Lung volume reduction surgery: an overview Cirurgia redutora de volume pulmonar: uma revisão

    Directory of Open Access Journals (Sweden)

    Rodrigo Afonso da Silva Sardenberg

    2010-01-01

    Full Text Available This study intends to review the literature on the efficacy, safety and feasibility of lung volume reduction surgery (LVRS in patients with advanced emphysema. Studies on LVRS from January 1995 to December 2009 were included by using Pubmed (MEDLINE and Cochrane Library literature in English. Search words such as lung volume reduction surgery or lung reduction surgery, pneumoplasty or reduction pneumoplasty, COPD or chronic obstructive pulmonary disease and surgery, were used. We also compared medical therapy and surgical technique. Studies consisting of randomized controlled trials, controlled clinical trials (randomized and nonrandomized, reviews and case series were analyzed. Questions regarding validity of the early clinical reports, incomplete follow-up bias, selection criteria and survival, confounded the interpretation of clinical data on LVRS. Patients with upper, lower and diffuse distribution of emphysema were included; we also analyzed as key points perioperative morbidity and mortality and lung function measurement as FEV1. Bullous emphysema was excluded from this review. Surgical approach included median sternotomy, unilateral or bilateral thoracotomy, and videothoracoscopy with stapled or laser ablation. Results of prospective randomized trials between medical management and LVRS are essential before final assessment can be established.O objetivo deste estudo é revisar a literatura acerca da eficácia, segurança e viabilidade da cirurgia redutora de volume pulmonar (CRVP em pacientes com enfisema pulmonar avançado. Estudos de CRVP de janeiro de 1995 a dezembro de 2009 foram incluídos através de pesquisa na Pubmed (MEDLINE e Cochrane Library, na literatura inglesa. Palavras de busca tais como lung volume reduction surgery ou lung reduction surgery, pneumoplasty ou reduction pneumoplasty, COPD ou chronic obstructive pulmonary disease e surgery foram utilizadas. Também realizamos comparação entre terapia médica e cir

  19. Annual review of fluid mechanics. Volume 23

    International Nuclear Information System (INIS)

    Lumley, J.L.; Van Dyke, M.; Reed, H.L.

    1991-01-01

    Recent advances in theoretical, experimental, and computational fluid mechanics are discussed in a collection of annual review essays. Topics addressed include Lagrangian ocean studies, drag reduction in nature, the hydraulics of rotating strait and sill flow, analytical methods for the development of Reynolds-stress closures in turbulence, and exact solutions of the Navier-Stokes equations. Consideration is given to the theory of hurricanes, flow phenomena in CVD of thin films, particle-imaging techniques for experimental fluid mechanics, symmetry and symmetry-breaking bifurcations in fluid dynamics, turbulent mixing in stratified fluids, numerical simulation of transition in wall-bounded shear flows, fractals and multifractals in fluid turbulence, and coherent motions in the turbulent boundary layer

  20. Drug and Alcohol Studies (Volume 5: Interventions)

    OpenAIRE

    MacGregor, S; Thom, B

    2014-01-01

    VOLUME FIVE: INTERVENTIONS Natural Recovery from Alcohol Problems Harald Klingemann School-Based Programmes to Prevent Alcohol, Tobacco and Other Drug Use Gilbert Botvin and Kenneth Griffin Community Prevention of Alcohol Problems Harold Holder Can Screening and Brief Intervention Lead to Population-Level Reductions in Alcohol-Related Harm? Nick Heather Sharpening the Focus of Alcohol Policy from Aggregate Consumption to Harm and Risk Reduction Tim Stockwell et al A Review of the Efficacy and...

  1. Review of air quality modeling techniques. Volume 8

    International Nuclear Information System (INIS)

    Rosen, L.C.

    1977-01-01

    Air transport and diffusion models which are applicable to the assessment of the environmental effects of nuclear, geothermal, and fossil-fuel electric generation are reviewed. The general classification of models and model inputs are discussed. A detailed examination of the statistical, Gaussian plume, Gaussian puff, one-box and species-conservation-of-mass models is given. Representative models are discussed with attention given to the assumptions, input data requirement, advantages, disadvantages and applicability of each

  2. Altitude Acclimatization and Blood Volume: Effects of Exogenous Erythrocyte Volume Expansion

    National Research Council Canada - National Science Library

    Sawka, M

    1996-01-01

    ...: (a) altitude acclimatization effects on erythrocyte volume and plasma volume; (b) if exogenous erythrocyte volume expansion alters subsequent erythrocyte volume and plasma volume adaptations; (c...

  3. AFRICAN JOURNAL OF ECONOMIC REVIEW

    African Journals Online (AJOL)

    Dr Kazungu

    African Journal of Economic Review, Volume IV, Issue 1, January 2016 ..... owned by the Central Government through Forestry and Beekeeping Division of the Ministry of ...... American Statistical Association, 84(408), 862-874. Heckman, J.

  4. Reserve Component Manpower Readiness and Mobilization Policy. Volume 2. Based on the Colloquium on Mobilization with Special Emphasis on Guard and Reserve Components, 1-4 November 1983

    Science.gov (United States)

    1984-03-16

    of Liberal Arts Rand Graduate Institute Syracuse Univ., College of Arts & Sciences Texas ASM Univ., College of Liberal Arts Tulane Univ., School of...and actuarial factors. Because tne Services have inadequate ,»rsonnel management data on the Reserve retiree population, inventory changes are...Manpower Data Center (DMDC) Office of the DoD Actuary and the respective service FY84-88 Program Objective Memorandum (POM). K/« cjr

  5. Advances in Reactor physics, mathematics and computation. Volume 3

    Energy Technology Data Exchange (ETDEWEB)

    1987-01-01

    These proceedings of the international topical meeting on advances in reactor physics, mathematics and computation, volume 3, are divided into sessions bearing on: - poster sessions on benchmark and codes: 35 conferences - review of status of assembly spectrum codes: 9 conferences - Numerical methods in fluid mechanics and thermal hydraulics: 16 conferences - stochastic transport and methods: 7 conferences.

  6. Best Practices for Chiropractic Care for Older Adults: A Systematic Review and Consensus Update.

    Science.gov (United States)

    Hawk, Cheryl; Schneider, Michael J; Haas, Mitchell; Katz, Paul; Dougherty, Paul; Gleberzon, Brian; Killinger, Lisa Z; Weeks, John

    2017-05-01

    The purpose of this study was to update evidence-based recommendations on the best practices for chiropractic care of older adults. The project consisted of a systematic literature review and a consensus process. The following were searched from October 2009 through January 2016: MEDLINE, Index to Chiropractic Literature, CINAHL (Cumulative Index to Nursing and Allied Health Literature), AMED (Allied and Complementary Medicine Database), Alt HealthWatch, Cochrane Database of Systematic Reviews, and Cochrane Registry of Controlled Trials. Search terms were: (manipulation, spinal OR manipulation, chiropractic OR chiropract*) AND (geriatric OR "older adult*"). Two reviewers independently screened articles and abstracts using inclusion and exclusion criteria. The systematic review informed the project steering committee, which revised the previous recommendations. A multidisciplinary panel of experts representing expertise in practice, research, and teaching in a variety of health professions serving older adults rated the revised recommendations. The RAND Corporation/University of California, Los Angeles methodology for a modified Delphi consensus process was used. A total of 199 articles were found; after exclusion criteria were applied, 6 articles about effectiveness or efficacy and 6 on safety were added. The Delphi process was conducted from April to June 2016. Of the 37 Delphi panelists, 31 were DCs and 6 were other health care professionals. Three Delphi rounds were conducted to reach consensus on all 45 statements. As a result, statements regarding the safety of manipulation were strengthened and additional statements were added recommending that DCs advise patients on exercise and that manipulation and mobilization contribute to general positive outcomes beyond pain reduction only. This document provides a summary of evidence-informed best practices for doctors of chiropractic for the evaluation, management, and manual treatment of older adult patients

  7. Constellation Program: Lessons Learned. Volume 1; Executive Summary

    Science.gov (United States)

    Rhatigan, Jennifer L. (Editor)

    2011-01-01

    This document (Volume I) provides an executive summary of the lessons learned from the Constellation Program. A companion Volume II provides more detailed analyses for those seeking further insight and information. In this volume, Section 1.0 introduces the approach in preparing and organizing the content to enable rapid assimilation of the lessons. Section 2.0 describes the contextual framework in which the Constellation Program was formulated and functioned that is necessary to understand most of the lessons. Context of a former program may seem irrelevant in the heady days of new program formulation. However, readers should take some time to understand the context. Many of the lessons would be different in a different context, so the reader should reflect on the similarities and differences in his or her current circumstances. Section 3.0 summarizes key findings developed from the significant lessons learned at the program level that appear in Section 4.0. Readers can use the key findings in Section 3.0 to peruse for particular topics, and will find more supporting detail and analyses in Section 4.0 in a topical format. Appendix A contains a white paper describing the Constellation Program formulation that may be of use to readers wanting more context or background information. The reader will no doubt recognize some very similar themes from previous lessons learned, blue-ribbon committee reviews, National Academy reviews, and advisory panel reviews for this and other large-scale human spaceflight programs; including Apollo, Space Shuttle, Shuttle/Mir, and the ISS. This could represent an inability to learn lessons from previous generations; however, it is more likely that similar challenges persist in the Agency structure and approach to program formulation, budget advocacy, and management. Perhaps the greatest value of these Constellation lessons learned can be found in viewing them in context with these previous efforts to guide and advise the Agency and its

  8. Improving Access to Behavioral Health Care for Remote Service Members and Their Families

    Science.gov (United States)

    2015-01-01

    video conferencing can help remote service members and dependents access needed care. These two promising avenues for improving access to care can...Corporation ISBN 978-0-8330-8872-7 www.rand.org Limited Print and Electronic Distribution Rights This document and trademark(s) contained herein are...RAND Corporation View document details Support RAND Browse Reports & Bookstore Make a charitable contribution Limited Electronic Distribution Rights

  9. RESIDENTIAL WOOD COMBUSTION TECHNOLOGY REVIEW VOLUME 1. TECHNICAL REPORT

    Science.gov (United States)

    This report gives results of a review of the current state-of-the-art of residential wood combustion (RWC). The key environmental parameter of concern was the air emission of particles. The technological status of all major RWC categories -- cordwood stoves, fireplaces, masonry h...

  10. Environmental Measurements Laboratory program review, December 1983

    International Nuclear Information System (INIS)

    Volchok, H.L.; de Planque, G.

    1984-03-01

    This volume contains all of the written material that was submitted to the panel of Reviewers in advance of a Program Review conducted by the US Department of Energy, Office of Health and Environmental Research at the Environmental Measurements Laboratory (EML) December 7-9, 1983. In addition to a general introduction there are nineteen papers grouped into the five broad program categories covering all of the scientific and engineering projects of the Laboratory: Natural Radioactivity and Radiation, Anthropogenic Radioactivity and Radiation, Non-nuclear, Quality Assurance, and Development and Support. These short articles, for the most part, focus on the rationale for EML's involvement in each project, emphasizing their relevance to the EML and Department of Energy missions. Project results and their interpretation were presented at the Review and can be found in the material referenced in this volume

  11. Lung volume reduction surgery for diffuse emphysema.

    Science.gov (United States)

    van Agteren, Joseph Em; Carson, Kristin V; Tiong, Leong Ung; Smith, Brian J

    2016-10-14

    Lung volume reduction surgery (LVRS) performed to treat patients with severe diffuse emphysema was reintroduced in the nineties. Lung volume reduction surgery aims to resect damaged emphysematous lung tissue, thereby increasing elastic properties of the lung. This treatment is hypothesised to improve long-term daily functioning and quality of life, although it may be costly and may be associated with risks of morbidity and mortality. Ten years have passed since the last version of this review was prepared, prompting us to perform an update. The objective of this review was to gather all available evidence from randomised controlled trials comparing the effectiveness of lung volume reduction surgery (LVRS) versus non-surgical standard therapy in improving health outcomes for patients with severe diffuse emphysema. Secondary objectives included determining which subgroup of patients benefit from LVRS and for which patients LVRS is contraindicated, to establish the postoperative complications of LVRS and its morbidity and mortality, to determine which surgical approaches for LVRS are most effective and to calculate the cost-effectiveness of LVRS. We identified RCTs by using the Cochrane Airways Group Chronic Obstructive Pulmonary Disease (COPD) register, in addition to the online clinical trials registers. Searches are current to April 2016. We included RCTs that studied the safety and efficacy of LVRS in participants with diffuse emphysema. We excluded studies that investigated giant or bullous emphysema. Two independent review authors assessed trials for inclusion and extracted data. When possible, we combined data from more than one study in a meta-analysis using RevMan 5 software. We identified two new studies (89 participants) in this updated review. A total of 11 studies (1760 participants) met the entry criteria of the review, one of which accounted for 68% of recruited participants. The quality of evidence ranged from low to moderate owing to an unclear risk

  12. Composite Differential Search Algorithm

    Directory of Open Access Journals (Sweden)

    Bo Liu

    2014-01-01

    Full Text Available Differential search algorithm (DS is a relatively new evolutionary algorithm inspired by the Brownian-like random-walk movement which is used by an organism to migrate. It has been verified to be more effective than ABC, JDE, JADE, SADE, EPSDE, GSA, PSO2011, and CMA-ES. In this paper, we propose four improved solution search algorithms, namely “DS/rand/1,” “DS/rand/2,” “DS/current to rand/1,” and “DS/current to rand/2” to search the new space and enhance the convergence rate for the global optimization problem. In order to verify the performance of different solution search methods, 23 benchmark functions are employed. Experimental results indicate that the proposed algorithm performs better than, or at least comparable to, the original algorithm when considering the quality of the solution obtained. However, these schemes cannot still achieve the best solution for all functions. In order to further enhance the convergence rate and the diversity of the algorithm, a composite differential search algorithm (CDS is proposed in this paper. This new algorithm combines three new proposed search schemes including “DS/rand/1,” “DS/rand/2,” and “DS/current to rand/1” with three control parameters using a random method to generate the offspring. Experiment results show that CDS has a faster convergence rate and better search ability based on the 23 benchmark functions.

  13. Sparse PDF Volumes for Consistent Multi-Resolution Volume Rendering

    KAUST Repository

    Sicat, Ronell Barrera

    2014-12-31

    This paper presents a new multi-resolution volume representation called sparse pdf volumes, which enables consistent multi-resolution volume rendering based on probability density functions (pdfs) of voxel neighborhoods. These pdfs are defined in the 4D domain jointly comprising the 3D volume and its 1D intensity range. Crucially, the computation of sparse pdf volumes exploits data coherence in 4D, resulting in a sparse representation with surprisingly low storage requirements. At run time, we dynamically apply transfer functions to the pdfs using simple and fast convolutions. Whereas standard low-pass filtering and down-sampling incur visible differences between resolution levels, the use of pdfs facilitates consistent results independent of the resolution level used. We describe the efficient out-of-core computation of large-scale sparse pdf volumes, using a novel iterative simplification procedure of a mixture of 4D Gaussians. Finally, our data structure is optimized to facilitate interactive multi-resolution volume rendering on GPUs.

  14. Incidence of radiation pneumonitis after thoracic irradiation: Dose-volume correlates

    International Nuclear Information System (INIS)

    Schallenkamp, John M.; Miller, Robert C.; Brinkmann, Debra H.; Foote, Tyler; Garces, Yolanda I.

    2007-01-01

    Purpose: To define clinical and dosimetric parameters correlated with the risk of clinically relevant radiation pneumonitis (RP) after thoracic radiotherapy. Methods and Materials: Records of consecutive patients treated with definitive thoracic radiotherapy were retrospectively reviewed for the incidence of RP of Grade 2 or greater by the Common Toxicity Criteria. Dose-volume histograms using total lung volume (TL) and TL minus gross tumor volume (TL-G) were created with and without heterogeneity corrections. Mean lung dose (MLD), effective lung volume (V eff ), and percentage of TL or TL-G receiving greater than or equal to 10, 13, 15, 20, and 30 Gy (V10-V30, respectively) were analyzed by logistic regression. Receiver operating characteristic (ROC) curves were generated to estimate RP predictive values. Results: Twelve cases of RP were identified in 92 eligible patients. Mean lung dose, V10, V13, V15, V20, and V eff were significantly correlated to RP. Combinations of MLD, V eff , V20, and V30 lost significance using TL-G and heterogeneity corrections. Receiver operating characteristic analysis determined V10 and V13 as the best predictors of RP risk, with a decrease in predictive value above those volumes. Conclusions: Intrathoracic radiotherapy should be planned with caution when using radiotherapy techniques delivering doses of 10 to 15 Gy to large lung volumes

  15. Sparse PDF Volumes for Consistent Multi-Resolution Volume Rendering

    KAUST Repository

    Sicat, Ronell Barrera; Kruger, Jens; Moller, Torsten; Hadwiger, Markus

    2014-01-01

    This paper presents a new multi-resolution volume representation called sparse pdf volumes, which enables consistent multi-resolution volume rendering based on probability density functions (pdfs) of voxel neighborhoods. These pdfs are defined

  16. World Energy Data System (WENDS). Volume I. Country data, AF-CO

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-06-01

    The World Energy Data System contains organized data on those countries and international organizations that may have critical impact on the world energy scene. Volumes 1 through 4 include energy-related information concerning 57 countries. Additional volumes (5 through 11) present review information on international organizations, summaries of energy-related international agreements, and fact sheets on nuclear facilities. Country data on Afghanistan, Algeria, Argentina, Australia, Austria, Bangladesh, Belgium, Bolivia, Brazil, Burma, Canada, China, and Colombia are included in Volume 1. The following topics are covered for most of the countries: economic, demographic, and educational profiles; energy policy; indigenous energy resources and uses; forecasts, demand, exports, imports of energy supplies; environmental considerations; power production facilities; energy industries; commercial applications of energy; research and development activities of energy; and international activities.

  17. Re-irradiation after gross total resection of recurrent glioblastoma. Spatial pattern of recurrence and a review of the literature as a basis for target volume definition

    Energy Technology Data Exchange (ETDEWEB)

    Straube, Christoph; Elpula, Greeshma [Technische Universitaet Muenchen (TUM), Department of Radiation Oncology, Klinikum rechts der Isar, Muenchen (Germany); Gempt, Jens; Gerhardt, Julia; Meyer, Bernhard [Technische Universitaet Muenchen (TUM), Department of Neurosurgery, Klinikum rechts der Isar, Muenchen (Germany); Bette, Stefanie; Zimmer, Claus [Technische Universitaet Muenchen (TUM), Department of Neuroradiology, Klinikum rechts der Isar, Muenchen (Germany); Schmidt-Graf, Friederike [Technische Universitaet Muenchen (TUM), Department of Neurology, Klinikum rechts der Isar, Muenchen (Germany); Combs, Stephanie E. [Technische Universitaet Muenchen (TUM), Department of Radiation Oncology, Klinikum rechts der Isar, Muenchen (Germany); Helmholtz Zentrum Muenchen, Institute for Innovative Radiotherapy (iRT), Department of Radiation Sciences (DRS), Oberschleissheim (Germany)

    2017-11-15

    Currently, patients with gross total resection (GTR) of recurrent glioblastoma (rGBM) undergo adjuvant chemotherapy or are followed up until progression. Re-irradiation, as one of the most effective treatments in macroscopic rGBM, is withheld in this situation, as uncertainties about the pattern of re-recurrence, the target volume, and also the efficacy of early re-irradiation after GTR exist. Imaging and clinical data from 26 consecutive patients with GTR of rGBM were analyzed. The spatial pattern of recurrences was analyzed according to the RANO-HGG criteria (''response assessment in neuro-oncology criteria for high-grade gliomas''). Progression-free (PFS) and overall survival (OS) were analyzed by the Kaplan-Meier method. Furthermore, a systematic review was performed in PubMed. All but 4 patients underwent adjuvant chemotherapy after GTR. Progression was diagnosed in 20 of 26 patients and 70% of recurrent tumors occurred adjacent to the resection cavity. The median extension beyond the edge of the resection cavity was 20 mm. Median PFS was 6 months; OS was 12.8 months. We propose a target volume containing the resection cavity and every contrast enhancing lesion as the gross tumor volume (GTV), a spherical margin of 5-10 mm to generate the clinical target volume (CTV), and a margin of 1-3 mm to generate the planning target volume (PTV). Re-irradiation of this volume is deemed to be safe and likely to prolong PFS. Re-irradiation is worth considering also after GTR, as the volumes that need to be treated are limited and re-irradiation has already proven to be a safe treatment option in general. The strategy of early re-irradiation is currently being tested within the GlioCave/NOA 17/Aro 2016/03 trial. (orig.) [German] Patienten mit einem rezidivierten Glioblastom (rGBM) werden, wenn eine komplette Resektion (GTR) des makroskopischen Rezidivs durchgefuehrt wurde, aktuell meist systemisch adjuvant behandelt oder einer engmaschigen Nachsorge

  18. Allocating Marine Expeditionary Unit Equipment to Minimize Shortfalls. Third Edition

    Science.gov (United States)

    2015-01-01

    research clients and sponsors. Support RAND Make a tax -deductible charitable contribution at www.rand.org/giving/contribute www.rand.org Library of... evasion and rescue plans prior to their flight, which would also be an important input for TRAP planning, particularly in cases in which there are...the scheme of maneuver, removing or avoiding obstacles and clearing threats is planned for as well. Large civilian populations are avoided whenever

  19. Perspectives on U.S. Competitiveness in Science and Technology: Conference Proceedings

    Science.gov (United States)

    2006-11-01

    that the provision of any good or service inevitably possesses both rival and non- rival aspects. A Beatles recording may be stored and communicated as...PDF document was made available from www.rand.org as a public service of the RAND Corporation. 6Jump down to document THE ARTS CHILD POLICY CIVIL...TECHNOLOGY SUBSTANCE ABUSE TERRORISM AND HOMELAND SECURITY TRANSPORTATION AND INFRASTRUCTURE WORKFORCE AND WORKPLACE The RAND Corporation is a nonprofit

  20. Military Review. Volume 91, Number 5, September-October 2011

    Science.gov (United States)

    2011-10-01

    REVIEW reader. The crisp tales have the stark realism of a fi rst-person lens. The author is at his absolute best when he introduces us to Marine...author has woven a narrative from poetry, memoir, and biography, as well as literary, cinematic , classical, and military history sources. He sees

  1. Correlation between orbital volume, body mass index, and eyeball position in healthy East asians.

    Science.gov (United States)

    Yoo, Jun Ho; Lee, Young Hen; Lee, Hwa; Kim, Jung Wan; Chang, Minwook; Park, Minsoo; Baek, Sehyun

    2013-05-01

    The objectives of this study were measure the orbital volume of healthy Koreans and analyze the differences between orbital tissue volume with respect to age and sex and to assess any correlation between body mass index (BMI), eyeball position, and orbital volume. We retrospectively evaluated the scan results of patients who had undergone orbital computed tomography scans between November 2010 and November 2011. We assessed the scan results of 184 orbits in 92 adults who had no pathology of the orbit. The individuals were classified into 3 groups with respect to age. Orbital volume, effective orbital volume (defined as the difference between orbital and eyeball volume), extraocular muscle volume, orbital fat volume, and transverse globe protrusion were recorded and analyzed. The records of the subjects were reviewed retrospectively, and BMI was calculated. A correlation analysis was performed to investigate the correlation between BMI, eyeball position, and orbital volume. Orbital tissue volume, with the exception of orbital fat volume, was larger in men compared with women. In both sexes, orbital fat volume increased with increasing age, whereas the other volumes decreased. Orbital tissue volumes increased with increasing BMI, but transverse globe protrusion was not significantly related to BMI. In addition, orbital volume and effective orbital volume were positively correlated with transverse globe protrusion. These results provide basic information about the effects of age, sex, and BMI on orbital volume and eyeball position in healthy Koreans. Furthermore, these results will be helpful in the diagnosis of orbital diseases and in planning orbital surgeries.

  2. Predictive and prognostic value of tumor volume and its changes during radical radiotherapy of stage III non-small cell lung cancer. A systematic review

    Energy Technology Data Exchange (ETDEWEB)

    Kaesmann, Lukas [University of Luebeck, Department of Radiation Oncology, Luebeck (Germany); Niyazi, Maximilian; Fleischmann, Daniel [LMU Munich, Department of Radiation Oncology, Munich (Germany); German Cancer Consortium (DKTK), partner site Munich, Munich (Germany); German Cancer Research Center (DKFZ), Heidelberg (Germany); Blanck, Oliver; Baumann, Rene [University Medical Center Schleswig-Holstein, Department of Radiation Oncology, Kiel (Germany); Baues, Christian; Klook, Lisa; Rosenbrock, Johannes; Trommer-Nestler, Maike [University Hospital of Cologne, Department of Radiotherapy, Cologne (Germany); Dobiasch, Sophie [Technische Universitaet Muenchen, Department of Radiation Oncology, Munich (Germany); Eze, Chukwuka [LMU Munich, Department of Radiation Oncology, Munich (Germany); Gauer, Tobias; Goy, Yvonne [University Medical Center Hamburg-Eppendorf, Department of Radiotherapy and Radio-Oncology, Hamburg (Germany); Giordano, Frank A.; Sautter, Lisa [University Medical Center Mannheim, Department of Radiation Oncology, Mannheim (Germany); Hausmann, Jan [University Medical Center Duesseldorf, Department of Radiation Oncology, Duesseldorf (Germany); Henkenberens, Christoph [Hannover Medical School, Department of Radiation and Special Oncology, Hannover (Germany); Kaul, David; Thieme, Alexander H. [Charite School of Medicine and University Hospital, Campus Virchow-Klinikum, Department of Radiation Oncology, Berlin (Germany); Krug, David; Schmitt, Daniela [University Hospital Heidelberg and National Center for Radiation Research in Oncology (NCRO) and Heidelberg Institute for Radiation Oncology (HIRO), Department of Radiation Oncology, Heidelberg (Germany); Maeurer, Matthias [University Medical Center Jena, Department of Radiation Oncology, Jena (Germany); Panje, Cedric M. [Kantonsspital St. Gallen, Department of Radiation Oncology, St. Gallen (Switzerland); Suess, Christoph [University Medical Center Regensburg, Department of Radiation Oncology, Regensburg (Germany); Ziegler, Sonia [University Medical Center Erlangen, Department of Radiation Oncology, Erlangen (Germany); Ebert, Nadja [University Medical Center Dresden, Department of Radiation Oncology, Dresden (Germany); OncoRay - National Center for Radiation Research in Oncology, Dresden (Germany); Medenwald, Daniel [Martin Luther University Halle-Wittenberg, Department of Radiation Oncology, Faculty of Medicine, Halle (Germany); Ostheimer, Christian [Martin Luther University Halle-Wittenberg, Department of Radiation Oncology, Faculty of Medicine, Halle (Germany); Klinik und Poliklinik fuer Strahlentherapie, Universitaetsklinikum Halle (Saale) (Germany); Collaboration: Young DEGRO Trial Group

    2018-02-15

    Lung cancer remains the leading cause of cancer-related mortality worldwide. Stage III non-small cell lung cancer (NSCLC) includes heterogeneous presentation of the disease including lymph node involvement and large tumour volumes with infiltration of the mediastinum, heart or spine. In the treatment of stage III NSCLC an interdisciplinary approach including radiotherapy is considered standard of care with acceptable toxicity and improved clinical outcome concerning local control. Furthermore, gross tumour volume (GTV) changes during definitive radiotherapy would allow for adaptive replanning which offers normal tissue sparing and dose escalation. A literature review was conducted to describe the predictive value of GTV changes during definitive radiotherapy especially focussing on overall survival. The literature search was conducted in a two-step review process using PubMed registered /Medline registered with the key words ''stage III non-small cell lung cancer'' and ''radiotherapy'' and ''tumour volume'' and ''prognostic factors''. After final consideration 17, 14 and 9 studies with a total of 2516, 784 and 639 patients on predictive impact of GTV, GTV changes and its impact on overall survival, respectively, for definitive radiotherapy for stage III NSCLC were included in this review. Initial GTV is an important prognostic factor for overall survival in several studies, but the time of evaluation and the value of histology need to be further investigated. GTV changes during RT differ widely, optimal timing for re-evaluation of GTV and their predictive value for prognosis needs to be clarified. The prognostic value of GTV changes is unclear due to varying study qualities, re-evaluation time and conflicting results. The main findings were that the clinical impact of GTV changes during definitive radiotherapy is still unclear due to heterogeneous study designs with varying quality

  3. Surgery for constipation: systematic review and practice recommendations: Graded practice and future research recommendations.

    Science.gov (United States)

    Knowles, C H; Grossi, U; Horrocks, E J; Pares, D; Vollebregt, P F; Chapman, M; Brown, S; Mercer-Jones, M; Williams, A B; Yiannakou, Y; Hooper, R J; Stevens, N; Mason, J

    2017-09-01

    This manuscript forms the final of seven that address the surgical management of chronic constipation (CC) in adults. The content coalesces results from the five systematic reviews that precede it and of the European Consensus process to derive graded practice recommendations (GPR). Summary of review data, development of GPR and future research recommendations as outlined in detail in the 'introduction and methods' paper. The overall quality of data in the five reviews was poor with 113/156(72.4%) of included studies providing only level IV evidence and only four included level I RCTs. Coalescence of data from the five procedural classes revealed that few firm conclusions could be drawn regarding procedural choice or patient selection: no single procedure dominated in addressing dynamic structural abnormalities of the anorectum and pelvic floor with each having similar overall efficacy. Of one hundred 'prototype' GPRs developed by the clinical guideline group, 85/100 were deemed 'appropriate' based on the independent scoring of a panel of 18 European experts and use of RAND-UCLA consensus methodology. The remaining 15 were all deemed uncertain. Future research recommendations included some potential RCTs but also a strong emphasis on delivery of large multinational high-quality prospective cohort studies. While the evidence base for surgery in CC is poor, the widespread European consensus for GPRs is encouraging. Professional bodies have the opportunity to build on this work by supporting the efforts of their membership to help convert the documented recommendations into clinical guidelines. © 2017 The Authors. Colorectal Disease published by John Wiley & Sons Ltd on behalf of Association of Coloproctology of Great Britain and Ireland.

  4. Military Review. Volume 91, Number 3, May-June 2011

    Science.gov (United States)

    2011-06-01

    REVIEW unexamined haste.10 An article in Newsweek in September 2009 went so far as to categorize the drones as “weapons porn .”11 This view of surgical... Porn : The Greatest, Weirdest, Coolest Hardware in the American Arsenal,” Newsweek, 23 September 2009, <http://www.newsweek. com/id/215823>. 12. Kathy

  5. Lodhi 5 Properties Investments CC v FirstRand Bank Limited [2015] 3 All SA 32 (SCA and the Enforcement of Islamic Banking Law in South Africa

    Directory of Open Access Journals (Sweden)

    Maphuti David Tuba

    2017-03-01

    Full Text Available On 22 May 2015, the Supreme Court of Appeal (SCA handed down a judgment in the matter of Lodhi 5 Properties Investments CC v FirstRand Bank Limited [2015] 3 All SA 32 (SCA. This judgement considered whether the prohibition against the charging of interest on a loan in terms of Islamic law (Sharia law may be a defence for a claim for mora interest in terms of a loan agreement. This note critically discusses the judgment in the light of the approach adopted by the SCA with regard to addressing a dispute arising from a contract that has Islamic law as a governing law. As this is the first case to come before the SCA in South Africa, this note critically analyses how the court discussed the principles of Islamic law as applicable to the dispute between the parties. In particular, it questions the court's assertion that a claim for mora interest has nothing to do with and is not affected by the Sharia law's prohibition against payment of interest on a loan debt. It also looks at the SCA's approach (as a common law court with regard to the enforcement of the principles of Islamic banking law. The judgment raises important issues regarding the enforceability of Islamic finance law and therefore merits discussion in the context of the continuing growth and expansion of Islamic banking and finance law in South Africa.

  6. Tranexamic Acid Reduced the Percent of Total Blood Volume Lost During Adolescent Idiopathic Scoliosis Surgery.

    Science.gov (United States)

    Jones, Kristen E; Butler, Elissa K; Barrack, Tara; Ledonio, Charles T; Forte, Mary L; Cohn, Claudia S; Polly, David W

    2017-01-01

    Multilevel posterior spine fusion is associated with significant intraoperative blood loss. Tranexamic acid is an antifibrinolytic agent that reduces intraoperative blood loss. The goal of this study was to compare the percent of total blood volume lost during posterior spinal fusion (PSF) with or without tranexamic acid in patients with adolescent idiopathic scoliosis (AIS). Thirty-six AIS patients underwent PSF in 2011-2014; the last half (n=18) received intraoperative tranexamic acid. We retrieved relevant demographic, hematologic, intraoperative and outcomes information from medical records. The primary outcome was the percent of total blood volume lost, calculated from estimates of intraoperative blood loss (numerator) and estimated total blood volume per patient (denominator, via Nadler's equations). Unadjusted outcomes were compared using standard statistical tests. Tranexamic acid and no-tranexamic acid groups were similar (all p>0.05) in mean age (16.1 vs. 15.2 years), sex (89% vs. 83% female), body mass index (22.2 vs. 20.2 kg/m2), preoperative hemoglobin (13.9 vs. 13.9 g/dl), mean spinal levels fused (10.5 vs. 9.6), osteotomies (1.6 vs. 0.9) and operative duration (6.1 hours, both). The percent of total blood volume lost (TBVL) was significantly lower in the tranexamic acid-treated vs. no-tranexamic acid group (median 8.23% vs. 14.30%, p = 0.032); percent TBVL per level fused was significantly lower with tranexamic acid than without it (1.1% vs. 1.8%, p=0.048). Estimated blood loss (milliliters) was similar across groups. Tranexamic acid significantly reduced the percentage of total blood volume lost versus no tranexamic acid in AIS patients who underwent PSF using a standardized blood loss measure.Level of Evidence: 3. Institutional Review Board status: This medical record chart review (minimal risk) study was approved by the University of Minnesota Institutional Review Board.

  7. Early Results on Activations and the Earnings of Reservists

    Science.gov (United States)

    2005-01-01

    compensation for the additional inconvenience, effort, and danger of such deployments. In the language of labor economics , they could be viewed as...Draft Lottery: Evidence from Social Security Administrative Records,” American Economic Review, June 1990, reprinted in Labor Economics , O. Ashenfelter... Labor Economics , January 1994. Asch, Beth J., and James R. Hosek. 1999. Military Compensation: Trends and Policy Options. Santa Monica, CA: RAND

  8. Annual review of fluid mechanics. Volume 15

    International Nuclear Information System (INIS)

    Van Dyke, M.; Wehausen, J.V.; Lumley, J.L.

    1983-01-01

    A survey of experimental results and analytical techniques for modelling various flows and the behavior of flows around flown-driven machinery is presented. Attention is given to analytical models for wind flows and power extraction by horizontal axis wind turbines. The phenomena occurring in the impact of compressible fluids with a solid body are described, as are the instabilities, pattern formation, and turbulence in flames. Homogeneous turbulence is explored, theories for autorotation by falling bodies are discussed, and attention is devoted to theoretical models for magneto-atmospheric waves and their presence in solar activity. The design characteristics of low Reynolds number airfoils are explored, and numerical and fluid mechanics formulations for integrable, chaotic, and turbulent vortex motion in two-dimensional flows are reviewed. Finally, measurements and models of turbulent wall jets for engineering purposes are examined

  9. Proceedings of the Advanced Turbine Systems Annual Program Review meeting. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-10-01

    Goal of the 8-year program are to develop cleaner, more efficient, and less expensive gas turbine systems for utility and industrial electric power generation, cogeneration, and mechanical drive units. The conference is held annually for energy executives, engineers, scientists, and other interested parties in industry, academia, and Government. This volume contains 28 poster presentations and appendices; the poster papers are processed separately for the data base.

  10. CLIMA 2016 - proceedings of the 12th REHVA World Congress:volume 6

    OpenAIRE

    2016-01-01

    CLIMA 2016, 12th REHVA World Congress 2016 in Aalborg north of Denmark. Full reviewed papers presented at CLIMA 2016 is published in the conference proceedings. This volume contains the sessions number 24 + 25 +26 + 27 + 28 +29 + 30 from track "Building Performance".

  11. CLIMA 2016 - proceedings of the 12th REHVA World Congress:volume 3

    OpenAIRE

    2016-01-01

    CLIMA 2016, 12th REHVA World Congress 2016 in Aalborg north of Denmark. Full reviewed papers presented at CLIMA 2016 is published in the conference proceedings.This volume contains the sessions number 8 + 9 + 10 + 11 + 12 + 13 from track "Sustainable Energy".

  12. Natural Computing in Computational Finance Volume 4

    CERN Document Server

    O’Neill, Michael; Maringer, Dietmar

    2012-01-01

    This book follows on from Natural Computing in Computational Finance  Volumes I, II and III.   As in the previous volumes of this series, the  book consists of a series of  chapters each of  which was selected following a rigorous, peer-reviewed, selection process.  The chapters illustrate the application of a range of cutting-edge natural  computing and agent-based methodologies in computational finance and economics.  The applications explored include  option model calibration, financial trend reversal detection, enhanced indexation, algorithmic trading,  corporate payout determination and agent-based modeling of liquidity costs, and trade strategy adaptation.  While describing cutting edge applications, the chapters are  written so that they are accessible to a wide audience. Hence, they should be of interest  to academics, students and practitioners in the fields of computational finance and  economics.  

  13. Brookhaven National Laboratory 2008 Site Environment Report Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Brookhaven National Laboratory

    2009-10-01

    Brookhaven National Laboratory (BNL) prepares an annual Site Environmental Report (SER) in accordance with DOE Order 231.1A, Environment, Safety and Health Reporting of the U.S. Department of Energy. The report is written to inform the public, regulators, employees, and other stakeholders of the Laboratory's environmental performance during the calendar year in review. Volume I of the SER summarizes environmental data; environmental management performance; compliance with applicable DOE, federal, state, and local regulations; and performance in restoration and surveillance monitoring programs. BNL has prepared annual SERs since 1971 and has documented nearly all of its environmental history since the Laboratory's inception in 1947. Volume II of the SER, the Groundwater Status Report, also is prepared annually to report on the status of and evaluate the performance of groundwater treatment systems at the Laboratory. Volume II includes detailed technical summaries of groundwater data and its interpretation, and is intended for internal BNL users, regulators, and other technically oriented stakeholders. A brief summary of the information contained in Volume II is included in this volume in Chapter 7, Groundwater Protection. Both reports are available in print and as downloadable files on the BNL web page at http://www.bnl.gov/ewms/ser/. An electronic version on compact disc is distributed with each printed report. In addition, a summary of Volume I is prepared each year to provide a general overview of the report, and is distributed with a compact disc containing the full report.

  14. The Voronoi volume and molecular representation of molar volume: equilibrium simple fluids.

    Science.gov (United States)

    Hunjan, Jagtar Singh; Eu, Byung Chan

    2010-04-07

    The Voronoi volume of simple fluids was previously made use of in connection with volume transport phenomena in nonequilibrium simple fluids. To investigate volume transport phenomena, it is important to develop a method to compute the Voronoi volume of fluids in nonequilibrium. In this work, as a first step to this goal, we investigate the equilibrium limit of the nonequilibrium Voronoi volume together with its attendant related molar (molal) and specific volumes. It is proved that the equilibrium Voronoi volume is equivalent to the molar (molal) volume. The latter, in turn, is proved equivalent to the specific volume. This chain of equivalences provides an alternative procedure of computing the equilibrium Voronoi volume from the molar volume/specific volume. We also show approximate methods of computing the Voronoi and molar volumes from the information on the pair correlation function. These methods may be employed for their quick estimation, but also provide some aspects of the fluid structure and its relation to the Voronoi volume. The Voronoi volume obtained from computer simulations is fitted to a function of temperature and pressure in the region above the triple point but below the critical point. Since the fitting function is given in terms of reduced variables for the Lennard-Jones (LJ) model and the kindred volumes (i.e., specific and molar volumes) are in essence equivalent to the equation of state, the formula obtained is a reduced equation state for simple fluids obeying the LJ model potential in the range of temperature and pressure examined and hence can be used for other simple fluids.

  15. Book review: Aquatic insect ecology: 1. Biology and habitat

    OpenAIRE

    Arnett, Ross H.

    2010-01-01

    Book Review: A comprehensive treatment of the ecology of aquatic insects in one place is needed for both students and researchers. Professor Ward is doing this in two volumes. The first volume covers the biology and habitats, as indicated in the subtitle, of the 13 insect orders that are either entirely aquatic at some stage, or those with some members aquatic at some stage. The second volume will be devoted entirely to the feeding ecology of these aquatic species.

  16. Emerging Threats to National Security

    National Research Council Canada - National Science Library

    Treverton, Gregory F

    2005-01-01

    Statement of Gregory F. Treverton, Director, Intelligence Policy Center, RAND Corporation, Associate Dean, Pardee RAND Graduate School, before the Permanent Select Committee on Intelligence, given before the United States...

  17. SPORT AND EXERCISE PHYSIOLOGY TESTING Volume one: Sport Testing Volume two: Exercise and Clinical Testing

    Directory of Open Access Journals (Sweden)

    Edward M. Winter

    2007-03-01

    Full Text Available DESCRIPTION The objective of the book is to discuss the theoretical and practical aspects of physiological testing in exercise and sports which is essential to evaluate and monitor developing exercise performance for athletes and public health, and improving quality of life for patients.A board of leading sport and exercise physiologists and scientists are gathered to discuss physiological assessments that have proven validity and reliability, both in sport and health relevant issues. Incidentally, it updates the reader about the current subjects of physiological exertion testing in both research and clinical procedures. Both volumes individually cover the increasing number of available research and review publications, and theoretical explanations are supported by practical examples. A step-by-step and/or checklist method is used in appropriate sections which make the guides more user-friendly than most. PURPOSE The first volume is designed to help readers develop an understanding of the essential concepts of sport specific testing whereas the second volume aims at making the exercise and clinical specific testing comprehensible, dealing with both technical terms and the theories underlying the importance of these tests. AUDIENCE As Guidelines books of the British Association of Sport and Exercise Sciences, it will be of interest to a wide range of students, researchers and practitioners in the sport and exercise disciplines whether they work in the laboratory or in the field. FEATURES The first volume features immediate practical requirements particularly in sport testing. It is composed of five parts with detailed sub-sections in all of them. The topics of the parts are: i general principles, ii methodological issues, iii general procedures, iv sport specific procedures, v special populations.The second volume is also presented in five parts, again with sub-sections in all of them, but considering the requirements in clinical and exercise

  18. Prehospital tidal volume influences hospital tidal volume: A cohort study.

    Science.gov (United States)

    Stoltze, Andrew J; Wong, Terrence S; Harland, Karisa K; Ahmed, Azeemuddin; Fuller, Brian M; Mohr, Nicholas M

    2015-06-01

    The purposes of the study are to describe current practice of ventilation in a modern air medical system and to measure the association of ventilation strategy with subsequent ventilator care and acute respiratory distress syndrome (ARDS). Retrospective observational cohort study of intubated adult patients (n = 235) transported by a university-affiliated air medical transport service to a 711-bed tertiary academic center between July 2011 and May 2013. Low tidal volume ventilation was defined as tidal volumes less than or equal to 8 mL/kg predicted body weight. Multivariable regression was used to measure the association between prehospital tidal volume, hospital ventilation strategy, and ARDS. Most patients (57%) were ventilated solely with bag valve ventilation during transport. Mean tidal volume of mechanically ventilated patients was 8.6 mL/kg predicted body weight (SD, 0.2 mL/kg). Low tidal volume ventilation was used in 13% of patients. Patients receiving low tidal volume ventilation during air medical transport were more likely to receive low tidal volume ventilation in the emergency department (P tidal volume (P = .840). Low tidal volume ventilation was rare during air medical transport. Air transport ventilation strategy influenced subsequent ventilation but was not associated with ARDS. Copyright © 2015 Elsevier Inc. All rights reserved.

  19. Coal liquefaction: A research and development needs assessment: Final report, Volume II

    Energy Technology Data Exchange (ETDEWEB)

    Schindler, H.D.; Burke, F.P.; Chao, K.C.; Davis, B.H.; Gorbaty, M.L.; Klier, K.; Kruse, C.W.; Larsen, J.W.; Lumpkin, R.E.; McIlwain, M.E.; Wender, I.; Stewart, N.

    1989-03-01

    Volume II of this report on an assessment of research needs for coal liquefaction contains reviews of the five liquefaction technologies---direct, indirect, pyrolysis, coprocessing, and bioconversion. These reviews are not meant to be encyclopedic; several outstanding reviews of liquefaction have appeared in recent years and the reader is referred to these whenever applicable. Instead, these chapters contain reviews of selected topics that serve to support the panel's recommendations or to illustrate recent accomplishments, work in progress, or areas of major research interest. At the beginning of each of these chapters is a brief introduction and a summary of the most important research recommendations brought out during the panel discussions and supported by the material presented in the review. A review of liquefaction developments outside the US is included. 594 refs., 100 figs., 60 tabs.

  20. [Evaluation of tidal volume delivered by ventilators during volume-controlled ventilation].

    Science.gov (United States)

    Zhou, Juan; Yan, Yong; Cao, Desen

    2014-12-01

    To study the ways which ensure the delivery of enough tidal volume to patients under various conditions close to the demand of the physician. The volume control ventilation model was chosen, and the simulation lung type was active servo lung ASL 5000 or Michigan lung 1601. The air resistance, air compliance and lung type in simulation lungs were set. The tidal volume was obtained from flow analyzer PF 300. At the same tidal volume, the displaying values of tidal volume of E5, Servo i, Evital 4, and Evital XL ventilators with different lung types of patient, compliance of gas piping, leakage, gas types, etc. were evaluated. With the same setting tidal volume of a same ventilator, the tidal volume delivered to patients was different with different lung types of patient, compliance of gas piping, leakage, gas types, etc. Reducing compliance and increasing resistance of the patient lungs caused high peak airway pressure, the tidal volume was lost in gas piping, and the tidal volume be delivered to the patient lungs was decreased. If the ventilator did not compensate to leakage, the tidal volume delivered to the patient lungs was decreased. When the setting gas type of ventilator did not coincide with that applying to the patient, the tidal volume be delivered to the patient lungs might be different with the setting tidal volume of ventilator. To ensure the delivery of enough tidal volume to patients close to the demand of the physician, containable factors such as the compliance of gas piping, leakage, and gas types should be controlled.

  1. Thanking our peer reviewers

    Directory of Open Access Journals (Sweden)

    Storey Alan

    2013-03-01

    Full Text Available Contributing reviewers As 2013 commences I would like to take a moment to reflect and recognize the peer reviewers that made the previous year possible. Listed below are those people who reviewed for Molecular Cancer last year. All are generous individuals who donated their time to assessing and improving our authors’ submissions. Your combined efforts have been invaluable to the editorial staff in maintaining the continued success of the journal in the Open Access forum. The editors of Molecular Cancer would like to thank all the reviewers who contributed to the journal in Volume 11 (2012 by participating in the review process - taking time out of your busy schedules and even to volunteer - without your critical insights, hard work and support for the journal we wouldn’t be able to do what we do.

  2. Positive and negative volume-outcome relationships in the geriatric trauma population.

    Science.gov (United States)

    Matsushima, Kazuhide; Schaefer, Eric W; Won, Eugene J; Armen, Scott B; Indeck, Matthew C; Soybel, David I

    2014-04-01

    In trauma populations, improvements in outcome are documented in institutions with higher case volumes. However, it is not known whether improved outcomes are attributable to the case volume within specific higher-risk groups, such as the elderly, or to the case volume among all trauma patients treated by an institution. To test the hypothesis that outcomes of trauma care for geriatric patients are affected differently by the volume of geriatric cases and nongeriatric cases of an institution. This retrospective cohort study using a statewide trauma registry was set in state-designated levels 1 and 2 trauma centers in Pennsylvania. It included 39 431 eligible geriatric trauma patients (aged >65 years) in the Pennsylvania Trauma Outcomes Study. In-hospital mortality, major complications, and mortality after major complications (failure to rescue). Between 2001 and 2010, 39 431 geriatric trauma patients and 105 046 nongeriatric patients were captured in a review of outcomes in 20 state-designated levels 1 and 2 trauma centers. Larger volumes of geriatric trauma patients were significantly associated with lower odds of in-hospital mortality, major complications, and failure to rescue. In contrast, larger nongeriatric trauma volumes were significantly associated with higher odds of major complications in geriatric patients. Higher rates of in-hospital mortality, major complications, and failure to rescue were associated with lower volumes of geriatric trauma care and paradoxically with higher volumes of trauma care for younger patients. These findings offer the possibility that outcomes might be improved with differentiated pathways of care for geriatric trauma patients.

  3. Low-level radioactive waste in the northeast: revised waste volume projections

    International Nuclear Information System (INIS)

    1984-06-01

    The volume of low-level radioactive waste generated in the eleven Northeast states has undergone significant change since the inital 1982 analysis and projection. These revised projections incorporate improved data reporting and evidence of sharp declines in certain categories of waste. Volumes in the 1982-1983 period reflect waste shipped for disposal as reported by disposal site operators. Projected waste volumes represent waste intended for disposal. The recent dramatic changes in source reduction and waste management practices underscore the need for annual review of waste volume projections. The volume of waste shipped for off-site disposal has declined approximately 12% in two years, from an average 1,092,500 ft 3 annually in 1979 to 1981 to an average annual 956,500 ft 3 in 1982 to 1983; reactor waste disposal volumes declined by about 39,000 ft 3 or 7% during this period. Non-reactor waste volumes shipped for disposal declined by over 70,000 ft 3 or 15% during this period. The data suggest that generators increased their use of such management practices as source reduction, compaction, or, for carbon-14 and tritium, temporary storage followed by disposal as non-radioactive waste under the NRC de minimus standard effective March 1981. Using the Technical Subcommittee projection methodology, the volume of low-level waste produced annually in the eleven states, individually and collectively, is expected to increase through the year 2000, but at a significantly lower rate of increase than initially projected. By the year 2000, the Northeast is projected to generate 1,137,600 ft 3 of waste annually, an increase of about 20% over 1982 to 1983 average volume

  4. The economic impact of regional waste disposal on advanced volume reduction technologies

    International Nuclear Information System (INIS)

    McArthur, W.C.; Kniazewycz, B.G.

    1983-01-01

    Waste volume reduction has received increased emphasis over the past decade as annual operating costs have risen from $250,000/year to $3,500,000 for 1983. Emphasis has been given to developing and designing into new nuclear plants process and DAW volume reduction technologies such as fluidized-bed dryers incinerators, and evaporative-solidification systems. The basis for these systems was originally the correct perception that a crisis would be reached with the, then available, shallow land disposal sites which would increase costs substantially and possible jeopardize power plant operations. With the passage of the Low-Level Waste Policy Act of 1980 and increased emphasis on interim on-site storage of low-level waste, the ''economics of volume reduction'' are susceptible to increased uncertainties. This paper reviews some previous volume reduction economic analyses and evaluates the revised economics based upon the development of regional waste disposal sites, improved waste generation and processing practices, and the increased use of interim on-site storage. Several case studies are presented

  5. Career Education of Hearing-Impaired Students: A Review.

    Science.gov (United States)

    Bullis, Michael, Ed.; Watson, Douglas, Ed.

    This monograph reviews the many efforts that have been made in the fields of education and vocational rehabilitation to develop and refine career preparation services for hearing-impaired individuals. The following papers are included in the volume: "Career Education: A Literature Review," by Charlene Dwyer; "A Current Profile of Career Education…

  6. Principles and techniques of radiation hardening. Volume 2. Transient radiation effects in electronics (TREE)

    International Nuclear Information System (INIS)

    Rudie, N.J.

    1976-01-01

    The three-volume book is intended to serve as a review of the effects of thermonuclear explosion induced radiation (x-rays, gamma rays, and beta particles) and the resulting electromagnetic pulse (EMP). Volume 2 deals with the following topics: radiation effects on quartz crystals, tantalum capacitors, bipolar semiconductor devices and integrated circuits, field effect transistors, and miscellaneous electronic devices; hardening electronic systems to photon and neutron radiation; nuclear radiation source and/or effects simulation techniques; and radiation dosimetry

  7. Volume and Surface-Enhanced Volume Negative Ion Sources

    International Nuclear Information System (INIS)

    Stockli, M P

    2013-01-01

    H - volume sources and, especially, caesiated H - volume sources are important ion sources for generating high-intensity proton beams, which then in turn generate large quantities of other particles. This chapter discusses the physics and technology of the volume production and the caesium-enhanced (surface) production of H - ions. Starting with Bacal's discovery of the H - volume production, the chapter briefly recounts the development of some H - sources, which capitalized on this process to significantly increase the production of H - beams. Another significant increase was achieved in the 1990s by adding caesiated surfaces to supplement the volume-produced ions with surface-produced ions, as illustrated with other H - sources. Finally, the focus turns to some of the experience gained when such a source was successfully ramped up in H - output and in duty factor to support the generation of 1 MW proton beams for the Spallation Neutron Source. (author)

  8. Development of quality metrics for ambulatory pediatric cardiology: Transposition of the great arteries after arterial switch operation.

    Science.gov (United States)

    Baker-Smith, Carissa M; Carlson, Karina; Ettedgui, Jose; Tsuda, Takeshi; Jayakumar, K Anitha; Park, Matthew; Tede, Nikola; Uzark, Karen; Fleishman, Craig; Connuck, David; Likes, Maggie; Penny, Daniel J

    2018-01-01

    To develop quality metrics (QMs) for the ambulatory care of patients with transposition of the great arteries following arterial switch operation (TGA/ASO). Under the auspices of the American College of Cardiology Adult Congenital and Pediatric Cardiology (ACPC) Steering committee, the TGA/ASO team generated candidate QMs related to TGA/ASO ambulatory care. Candidate QMs were submitted to the ACPC Steering Committee and were reviewed for validity and feasibility using individual expert panel member scoring according to the RAND-UCLA methodology. QMs were then made available for review by the entire ACC ACPC during an "open comment period." Final approval of each QM was provided by a vote of the ACC ACPC Council. Patients with TGA who had undergone an ASO were included. Patients with complex transposition were excluded. Twelve candidate QMs were generated. Seven metrics passed the RAND-UCLA process. Four passed the "open comment period" and were ultimately approved by the Council. These included: (1) at least 1 echocardiogram performed during the first year of life reporting on the function, aortic dimension, degree of neoaortic valve insufficiency, the patency of the systemic and pulmonary outflows, the patency of the branch pulmonary arteries and coronary arteries, (2) neurodevelopmental (ND) assessment after ASO; (3) lipid profile by age 11 years; and (4) documentation of a transition of care plan to an adult congenital heart disease (CHD) provider by 18 years of age. Application of the RAND-UCLA methodology and linkage of this methodology to the ACPC approval process led to successful generation of 4 QMs relevant to the care of TGA/ASO pediatric patients in the ambulatory setting. These metrics have now been incorporated into the ACPC Quality Network providing guidance for the care of TGA/ASO patients across 30 CHD centers. © 2017 Wiley Periodicals, Inc.

  9. ŢARA ZĂRANDULUI CA PROIECŢIE SPAŢIALĂ MENTALĂ

    Directory of Open Access Journals (Sweden)

    Nicoleta DAVID

    2009-07-01

    Full Text Available The Land of Zărand as Metal Spatial Projection.The physical support of the Zărand mental space is represented by the morphology of the region, by the forestry domain (generator of a special type of behaviour and of peculiar occupations, by the mining activity (especially the one related to the gold-bearing veins and by the historical events that led to the heroic mythology. The stages in the development of the Land of Zărand into an open mental space took place gradually based on the transfer of influence from the Zărand Fortress towards the interior of the mountains, towards the future settlements with role of central place, namely Baia de Criş and Brad.

  10. Development of Automatic Visceral Fat Volume Calculation Software for CT Volume Data

    Directory of Open Access Journals (Sweden)

    Mitsutaka Nemoto

    2014-01-01

    Full Text Available Objective. To develop automatic visceral fat volume calculation software for computed tomography (CT volume data and to evaluate its feasibility. Methods. A total of 24 sets of whole-body CT volume data and anthropometric measurements were obtained, with three sets for each of four BMI categories (under 20, 20 to 25, 25 to 30, and over 30 in both sexes. True visceral fat volumes were defined on the basis of manual segmentation of the whole-body CT volume data by an experienced radiologist. Software to automatically calculate visceral fat volumes was developed using a region segmentation technique based on morphological analysis with CT value threshold. Automatically calculated visceral fat volumes were evaluated in terms of the correlation coefficient with the true volumes and the error relative to the true volume. Results. Automatic visceral fat volume calculation results of all 24 data sets were obtained successfully and the average calculation time was 252.7 seconds/case. The correlation coefficients between the true visceral fat volume and the automatically calculated visceral fat volume were over 0.999. Conclusions. The newly developed software is feasible for calculating visceral fat volumes in a reasonable time and was proved to have high accuracy.

  11. Management of low-level radioactive waste in the Southeast Compact Region: Volume 2, Management plan: Final report

    International Nuclear Information System (INIS)

    1985-07-01

    The Southeast Compact Commission for Low-Level Radioactive Waste Management has begun the development of a regional low-level radioactive waste management plan. They have reviewed and analyzed existing data on current low-level radioactive waste volumes shipped for disposal by generators in the Southeast region and have supplemented existing data by direct contact with State regulatory personnel, disposal site operators, and individual generators. The Commission has also projected the amounts and types of waste expected to require offsite disposal. This characterized data base and the projections of waste volumes and types through 1996 are included in this volume. Alternative disposal and treatment technologies were evaluated for management of the waste in the region. This evaluation consisted of a review of the literature concerning the several technologies in low level radioactive waste management. This information is summarized in Appendix A. 72 refs., 28 figs., 30 tabs

  12. Wind prices are down - but are they too low?

    International Nuclear Information System (INIS)

    Milborrow, D.

    1998-01-01

    The highly competitive nature of the NFFO and SRO bidding processes may be putting undue pressure on manufacturers' profit margins, restricting funds for investment and RandD. Taking the wider view, RandD in the wind industry is very modest relative to its output. Nevertheless, the wind industry is delivering increasingly reliable and cost effective wind turbines. The needs for further RandD are critically examined and the paper includes assessments of future wind energy price trends. (Author)

  13. Extending Depot Length and Intervals for DDG 51 Class Ships: Examining the 72 Month Operational Cycle

    Science.gov (United States)

    2016-01-01

    would inherit should it choose to extend the operational cycle of the DDG-51 fleet. Our model does not project overall cost sav- ings in the long run for...clients and sponsors. Support RAND Make a tax -deductible charitable contribution at www.rand.org/giving/contribute www.rand.org Library of Congress...Class Ships: The 72-Month Cycle removal of the crew during the execution of maintenance to mitigate costs in this employment approach. This research

  14. Recycle operations as a methodology for radioactive waste volume reduction

    International Nuclear Information System (INIS)

    Rasmussen, G.A.

    1985-01-01

    The costs for packaging, transportation and burial of low-level radioactive metallic waste have become so expensive that an alternate method of decontamination for volume reduction prior to disposal can now be justified. The operation of a large-scale centralized recycle center for decontamination of selected low level radioactive waste has been proven to be an effective method for waste volume reduction and for retrieving valuable materials for unlimited use. The centralized recycle center concept allows application of state-of-the-art decontamination technology resulting in a reduction in utility disposal costs and a reduction in overall net amount of material being buried. Examples of specific decontamination process activities at the centralized facility will be reviewed along with a discussion of the economic impact of decontamination for recycling and volume reduction. Based on almost two years of operation of a centralized decontamination facility, a demonstrated capability exists. The concept has been cost effective and proves that valuable resources can be recycled

  15. Technical Reviews and Audits for Systems, Equipment and Computer Software. Volume 1

    Science.gov (United States)

    2009-09-15

    acquisitions and technology developments. 2. This new-issue SMC standard comprises the text of The Aerospace Corporation report number TOR-2007( 8583 )-6414...TRA) Deskbook – DUSD(S&T) (May 2005) 17. IMP & IMS Preparation and Use Guide Version 0.9 (21 October 2005) 18. ISO /IEC STD 15939 Software...1521B, TOR-2007( 8583 )-6414_Volume 1. 110.2 Purpose A. The guidelines contained herein implement the Department of Defense Directive 4120.21

  16. Calculating regional tissue volume for hyperthermic isolated limb perfusion: Four methods compared.

    Science.gov (United States)

    Cecchin, D; Negri, A; Frigo, A C; Bui, F; Zucchetta, P; Bodanza, V; Gregianin, M; Campana, L G; Rossi, C R; Rastrelli, M

    2016-12-01

    Hyperthermic isolated limb perfusion (HILP) can be performed as an alternative to amputation for soft tissue sarcomas and melanomas of the extremities. Melphalan and tumor necrosis factor-alpha are used at a dosage that depends on the volume of the limb. Regional tissue volume is traditionally measured for the purposes of HILP using water displacement volumetry (WDV). Although this technique is considered the gold standard, it is time-consuming and complicated to implement, especially in obese and elderly patients. The aim of the present study was to compare the different methods described in the literature for calculating regional tissue volume in the HILP setting, and to validate an open source software. We reviewed the charts of 22 patients (11 males and 11 females) who had non-disseminated melanoma with in-transit metastases or sarcoma of the lower limb. We calculated the volume of the limb using four different methods: WDV, tape measurements and segmentation of computed tomography images using Osirix and Oncentra Masterplan softwares. The overall comparison provided a concordance correlation coefficient (CCC) of 0.92 for the calculations of whole limb volume. In particular, when Osirix was compared with Oncentra (validated for volume measures and used in radiotherapy), the concordance was near-perfect for the calculation of the whole limb volume (CCC = 0.99). With methods based on CT the user can choose a reliable plane for segmentation purposes. CT-based methods also provides the opportunity to separate the whole limb volume into defined tissue volumes (cortical bone, fat and water). Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Development of Quality Metrics in Ambulatory Pediatric Cardiology.

    Science.gov (United States)

    Chowdhury, Devyani; Gurvitz, Michelle; Marelli, Ariane; Anderson, Jeffrey; Baker-Smith, Carissa; Diab, Karim A; Edwards, Thomas C; Hougen, Tom; Jedeikin, Roy; Johnson, Jonathan N; Karpawich, Peter; Lai, Wyman; Lu, Jimmy C; Mitchell, Stephanie; Newburger, Jane W; Penny, Daniel J; Portman, Michael A; Satou, Gary; Teitel, David; Villafane, Juan; Williams, Roberta; Jenkins, Kathy

    2017-02-07

    The American College of Cardiology Adult Congenital and Pediatric Cardiology (ACPC) Section had attempted to create quality metrics (QM) for ambulatory pediatric practice, but limited evidence made the process difficult. The ACPC sought to develop QMs for ambulatory pediatric cardiology practice. Five areas of interest were identified, and QMs were developed in a 2-step review process. In the first step, an expert panel, using the modified RAND-UCLA methodology, rated each QM for feasibility and validity. The second step sought input from ACPC Section members; final approval was by a vote of the ACPC Council. Work groups proposed a total of 44 QMs. Thirty-one metrics passed the RAND process and, after the open comment period, the ACPC council approved 18 metrics. The project resulted in successful development of QMs in ambulatory pediatric cardiology for a range of ambulatory domains. Copyright © 2017 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  18. APPLIED MECHANICS REVIEWS, WADEX WORD AND AUTHOR INDEX, VOLUME XVI, 1963,

    Science.gov (United States)

    Author inDEX ) an IBM 1401 prepared mechanical index, extension of KWIC. WADEX usable for browsing and searching. This second WADEX is based on 8,000 titles of APPLIED MECHANICS REVIEWS (AMR), Vol. 16, 1963, an international critical review magazine. In WADEX, titles printed fully with author names, and as many lines used as necessary (60 characters per line). WADEX entry: word in title (except forbidden word) or author’s name. Alphabetically sequenced entries printed out of context. Words are single words or hypenated word pairs or ’Tagged Words’ (TW).

  19. Principles and techniques of radiation hardening. Volume 3. Electromagnetic pulse (EMP) and system generated EMP

    International Nuclear Information System (INIS)

    Rudie, N.J.

    1976-01-01

    The three-volume book is intended to serve as a review of the effects of thermonuclear explosion induced radiation (x-rays, gamma rays, and beta particles) and the resulting electromagnetic pulse (EMP). Volume 3 deals with the following topics: selected fundamentals of electromagnetic theory; EMP induced currents on antennas and cables; the EMP response of electronics; EMP hardening; EMP testing; injection currents; internal electromagnetic pulse (IEMP); replacement currents; and system generated electromagnetic pulse (SGEMP) hardening

  20. Clinical effectiveness of decongestive treatments on excess arm volume and patient-centered outcomes in women with early breast cancer-related arm lymphedema: a systematic review

    Science.gov (United States)

    Jeffs, Eunice; Ream, Emma; Taylor, Cath; Bick, Debra

    2018-01-01

    ABSTRACT Objective: To identify the effect of decongestive lymphedema treatment on excess arm volume or patient-centered outcomes in women presenting within either 12 months or a mean nine months of developing arm lymphedema following breast cancer treatment. Introduction: Lymphedema is a common consequence of breast cancer treatment requiring life-long treatment to reduce symptoms and prevent complications. Currently, evidence to inform the optimal decongestive lymphedema treatment package is lacking. Inclusion criteria: The review included studies on women who received lymphedema treatment within either 12 months or a mean of nine months of developing unilateral breast cancer-related arm lymphedema. The intervention was any decongestive lymphedema treatment delivered with the purpose of reducing arm lymphedema, compared to another form of lymphedema treatment (whether self or practitioner-administered), placebo or no treatment. The clinical outcome was excess arm volume; patient-centered outcomes were health-related quality of life, arm heaviness, arm function, patient-perceived benefit and satisfaction with treatment. Experimental study designs were eligible, including randomized and non-randomized controlled trials, quasi-experimental, prospective and retrospective before and after studies were considered. Methods: A three-step search strategy was utilized to find published and unpublished studies. The search identified studies published from the inception of each database to July 6, 2016. Reference lists were scanned to identify further eligible studies. Studies were critically appraised using appropriate standardized critical appraisal instruments from the Joanna Briggs Institute. Details describing each study and treatment results regarding outcomes of interest were extracted from papers included in the review using appropriate standardized data extraction tools from the Joanna Briggs Institute. Due to heterogeneity in included studies, results for similar

  1. Review: Devan Pillay, Gilbert M. Khadiagala, Prishani Naidoo and Roger Southall (eds, New South African Review 4: A Fragile Democracy – Twenty Years On (2014

    Directory of Open Access Journals (Sweden)

    Ian Taylor

    2015-01-01

    Full Text Available Review of the edited volume:Devan Pillay, Gilbert M. Khadiagala, Prishani Naidoo and Roger Southall (eds, New South African Review 4: A Fragile Democracy – Twenty Years On, Johannesburg: Wits University Press, 2014, ISBN 9781868147632, 380 pp.

  2. Breadth versus volume: Neurology outpatient clinic cases in medical education.

    Science.gov (United States)

    Albert, Dara V; Blood, Angela D; Park, Yoon Soo; Brorson, James R; Lukas, Rimas V

    2016-06-01

    This study examined how volume in certain patient case types and breadth across patient case types in the outpatient clinic setting are related to Neurology Clerkship student performance. Case logs from the outpatient clinic experience of 486 students from The University of Chicago Pritzker School of Medicine, USA, participating in the 4week Neurology Clerkship from July 2008 to June 2013 were reviewed. A total of 12,381 patient encounters were logged and then classified into 13 diagnostic categories. How volume of cases within categories and the breadth of cases across categories relate to the National Board of Medical Examiners Clinical Subject Examination for Neurology and a Neurology Clerkship Objective Structured Clinical Examination was analyzed. Volume of cases was significantly correlated with the National Board of Medical Examiners Clinical Subject Examination for Neurology (r=.290, pNeurology (r=.231, p=.017), however was not significantly correlated with any component of the Objective Structured Clinical Examination. Volume of cases correlated with higher performance on measures of specialty knowledge and clinical skill. Fewer relationships emerged correlating breadth of cases and performance on the same measures. This study provides guidance to educators who must decide how much emphasis to place on volume versus breadth of cases in outpatient clinic learning experiences. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Systematic review of dose-volume parameters in the prediction of esophagitis in thoracic radiotherapy

    International Nuclear Information System (INIS)

    Rose, Jim; Rodrigues, George; Yaremko, Brian; Lock, Michael; D'Souza, David

    2009-01-01

    Purpose: With dose escalation and increasing use of concurrent chemoradiotherapy, radiation esophagitis (RE) remains a common treatment-limiting acute side effect in the treatment of thoracic malignancies. The advent of 3DCT planning has enabled investigators to study esophageal dose-volume histogram (DVH) parameters as predictors of RE. The purpose of this study was to assess published dosimetric parameters and toxicity data systematically in order to define reproducible predictors of RE, both for potential clinical use, and to provide recommendations for future research in the field. Materials and methods: We performed a systematic literature review of published studies addressing RE in the treatment of lung cancer and thymoma. Our search strategy included a variety of electronic medical databases, textbooks and bibliographies. Both prospective and retrospective clinical studies were included. Information relating to the relationship among measured dosimetric parameters, patient demographics, tumor characteristics, chemotherapy and RE was extracted and analyzed. Results: Eighteen published studies were suitable for analysis. Eleven of these assessed acute RE, while the remainder assessed both acute and chronic RE together. Heterogeneity of esophageal contouring practices, individual differences in information reporting and variability of RE outcome definitions were assessed. Well-described clinical and logistic modeling directly related V 35Gy , V 60Gy and SA 55Gy to clinically significant RE. Conclusions: Several reproducible dosimetric parameters exist in the literature, and these may be potentially relevant in the prediction of RE in the radiotherapy of thoracic malignancies. Further clarification of the predictive relationship between such standardized dosimetric parameters and observed RE outcomes is essential to develop efficient radiation treatment planning in locally advanced NSCLC in the modern concurrent chemotherapy and image-guided IMRT era.

  4. New Security and Justice Sector Partnership Models: Implications of the Arab Uprisings

    Science.gov (United States)

    2014-01-01

    contributions of several of our RAND colleagues. Emma Davies Cutrufello was instrumental collect- ing and analyzing the data for Chapter Two. Beth...Light of the Financial Crisis: A Critical Review, Development Centre Studies, OECD Publications, 2009, pp. 43–45. 3 Paul Collier, “Is Aid Oil? An...represent signifi- cant opportunities for burden sharing. Another area where there is potential for enhanced multilateral - ism and local ownership of SJSP

  5. Current Simulation Methods in Military Systems Vulnerability Assessment

    Science.gov (United States)

    1990-11-01

    milestones, Army leadership commissions numerous ad hoc studies to help with in-process reviews (IPRs), Program Objective Memorandum (POM) submissions...Picatinny Arsenal, NJ 07806-5000 24 No. of No. of Copis Organzan copip Organizatin Director I Commander Center for Night Vision and Electro-Optics US...QPes Organza inn ps Organizatin 6 Institute for Defense Analyses (IDA) I AFELM, The Rand Corporation ATTN: Mr. Irwin A. Kaufman ATTN: Library-D Mr

  6. Estimation of lung volume and pulmonary blood volume from radioisotopic images

    International Nuclear Information System (INIS)

    Kanazawa, Minoru

    1989-01-01

    Lung volume and pulmonary blood volume in man were estimated from the radioisotopic image using single photon emission computed tomography (SPECT). Six healthy volunteers were studied in a supine position with normal and altered lung volumes by applying continuous negative body-surface pressure (CNP) and by positive end-expiratory pressure (PEEP). 99m Tc labeled human serum albumin was administered as an aerosol to image the lungs. The CNP caused the diaphragm to be lowered and it increased the mean lung tissue volume obtained by SPECT from 3.09±0.49 l for baseline to 3.67±0.62 l for 10 cmH 2 O (p 2 O (p 2 O), respectively. The PEEP also increased the lung tissue volume to 3.68±0.68 l for 10 cmH 2 O as compared with the baseline (p 2 O PEEP. The lung tissue volume obtained by SPECT showed a positive correlation with functional residual capacity measured by the He dilution method (r=0.91, p 99m Tc-labeled red blood cells. The L/H ratio decreased after either the CNP or PEEP, suggesting a decrease in the blood volume per unit lung volume. However, it was suggested that the total pulmonary blood volume increased slightly either on the CNP (+7.4% for 10 cmH 2 O, p 2 O,p<0.05) when we extrapolated the L/H ratio to the whole lungs by multiplying the lung tissue volume obtained by SPECT. We concluded that SPECT could offer access to the estimation of lung volume and pulmonary blood volume in vivo. (author)

  7. An automated electronic system for managing radiation treatment plan peer review reduces missed reviews at a large, high-volume academic center.

    Science.gov (United States)

    Gabriel, Peter E; Woodhouse, Kristina D; Lin, Alexander; Finlay, Jarod C; Young, Richard B; Volz, Edna; Hahn, Stephen M; Metz, James M; Maity, Amit

    Assuring quality in cancer care through peer review has become increasingly important in radiation oncology. In 2012, our department implemented an automated electronic system for managing radiation treatment plan peer review. The purpose of this study was to compare the overall impact of this electronic system to our previous manual, paper-based system. In an effort to improve management, an automated electronic system for case finding and documentation of review was developed and implemented. The rates of missed initial reviews, late reviews, and missed re-reviews were compared for the pre- versus postelectronic system cohorts using Pearson χ 2 test and relative risk. Major and minor changes or recommendations were documented and shared with the assigned clinical provider. The overall rate of missed reviews was 7.6% (38/500) before system implementation versus 0.4% (28/6985) under the electronic system (P automated system. Missed re-reviews occurred in 23.1% (3/13) of courses in the preelectronic system cohort and 6.6% (10/152) of courses in the postelectronic system cohort (P = .034). Late reviews were more frequent during high travel or major holiday periods. Major changes were recommended in 2.2% and 2.8% in the pre- versus postelectronic systems, respectively. Minor changes were recommended in 5.3% of all postelectronic cases. The implementation of an automated electronic system for managing peer review in a large, complex department was effective in significantly reducing the number of missed reviews and missed re-reviews when compared to our previous manual system. Copyright © 2016 American Society for Radiation Oncology. Published by Elsevier Inc. All rights reserved.

  8. Measuring stone volume - three-dimensional software reconstruction or an ellipsoid algebra formula?

    Science.gov (United States)

    Finch, William; Johnston, Richard; Shaida, Nadeem; Winterbottom, Andrew; Wiseman, Oliver

    2014-04-01

    To determine the optimal method for assessing stone volume, and thus stone burden, by comparing the accuracy of scalene, oblate, and prolate ellipsoid volume equations with three-dimensional (3D)-reconstructed stone volume. Kidney stone volume may be helpful in predicting treatment outcome for renal stones. While the precise measurement of stone volume by 3D reconstruction can be accomplished using modern computer tomography (CT) scanning software, this technique is not available in all hospitals or with routine acute colic scanning protocols. Therefore, maximum diameters as measured by either X-ray or CT are used in the calculation of stone volume based on a scalene ellipsoid formula, as recommended by the European Association of Urology. In all, 100 stones with both X-ray and CT (1-2-mm slices) were reviewed. Complete and partial staghorn stones were excluded. Stone volume was calculated using software designed to measure tissue density of a certain range within a specified region of interest. Correlation coefficients among all measured outcomes were compared. Stone volumes were analysed to determine the average 'shape' of the stones. The maximum stone diameter on X-ray was 3-25 mm and on CT was 3-36 mm, with a reasonable correlation (r = 0.77). Smaller stones (15 mm towards scalene ellipsoids. There was no difference in stone shape by location within the kidney. As the average shape of renal stones changes with diameter, no single equation for estimating stone volume can be recommended. As the maximum diameter increases, calculated stone volume becomes less accurate, suggesting that larger stones have more asymmetric shapes. We recommend that research looking at stone clearance rates should use 3D-reconstructed stone volumes when available, followed by prolate, oblate, or scalene ellipsoid formulas depending on the maximum stone diameter. © 2013 The Authors. BJU International © 2013 BJU International.

  9. Cross-correlations in volume space: Differences between buy and sell volumes

    Science.gov (United States)

    Lee, Sun Young; Hwang, Dong Il; Kim, Min Jae; Koh, In Gyu; Kim, Soo Yong

    2011-03-01

    We study the cross-correlations of buy and sell volumes on the Korean stock market in high frequency. We observe that the pulling effects of volumes are as small as that of returns. The properties of the correlations of buy and sell volumes differ. They are explained by the degree of synchronization of stock volumes. Further, the pulling effects on the minimal spanning tree are studied. In minimal spanning trees with directed links, the large pulling effects are clustered at the center, not uniformly distributed. The Epps effect of buy and sell volumes are observed. The reversal of the cross-correlations of buy and sell volumes is also detected.

  10. Traumatic Spinal Injury: Global Epidemiology and Worldwide Volume.

    Science.gov (United States)

    Kumar, Ramesh; Lim, Jaims; Mekary, Rania A; Rattani, Abbas; Dewan, Michael C; Sharif, Salman Y; Osorio-Fonseca, Enrique; Park, Kee B

    2018-05-01

    Traumatic spinal injury (TSI) results from injury to bony, ligamentous, and/or neurologic structures of the spinal column and can cause significant morbidity and mortality. The global burden of TSI is poorly understood, so we performed a systematic review and meta-analysis to estimate the global volume of TSI. We performed a systematic review through PubMed, Embase, and Cochrane Databases on TSI studies reported from 2000 to 2016. Collected data were used to perform a meta-analysis to estimate the annual incidence of TSI across World Health Organization regions and World Bank income groups using random-effect models. Incorporating global population figures, the annual worldwide volume of TSI was estimated. A total of 102 studies were included in the systematic review and 19 studies in the meta-analysis. The overall global incidence of TSI was 10.5 cases per 100,000 persons, resulting in an estimated 768,473 [95% confidence interval, 597,213-939,732] new cases of TSI annually worldwide. The incidence of TSI was higher in low- and middle-income countries (8.72 per 100,000 persons) compared with high-income countries (13.69 per 100,000 persons). Road traffic accidents, followed by falls, were the most common mechanism of TSI worldwide. Overall, 48.8% of patients with TSI required surgery. TSI is a major source of morbidity and mortality throughout the world. Largely preventable mechanisms, including road traffic accidents and falls, are the main causes of TSI globally. Further investigation is needed to delineate local and regional TSI incidences and causes, especially in low- and middle-income countries. Copyright © 2018 Elsevier Inc. All rights reserved.

  11. LLE Review 101 (October-December 2004)

    Energy Technology Data Exchange (ETDEWEB)

    Shmayda, W. T. [editor

    2005-03-01

    This volume of the LLE Review, covering October to December 2004, highlights the significance of shaped adiabats to inertial confinement fusion. Theory suggests that inertial confinement fusion (ICF) capsules compressed by shaped adiabats will exhibit improved hydrodynamic stability.

  12. A multi-criteria approach to camera motion design for volume data animation.

    Science.gov (United States)

    Hsu, Wei-Hsien; Zhang, Yubo; Ma, Kwan-Liu

    2013-12-01

    We present an integrated camera motion design and path generation system for building volume data animations. Creating animations is an essential task in presenting complex scientific visualizations. Existing visualization systems use an established animation function based on keyframes selected by the user. This approach is limited in providing the optimal in-between views of the data. Alternatively, computer graphics and virtual reality camera motion planning is frequently focused on collision free movement in a virtual walkthrough. For semi-transparent, fuzzy, or blobby volume data the collision free objective becomes insufficient. Here, we provide a set of essential criteria focused on computing camera paths to establish effective animations of volume data. Our dynamic multi-criteria solver coupled with a force-directed routing algorithm enables rapid generation of camera paths. Once users review the resulting animation and evaluate the camera motion, they are able to determine how each criterion impacts path generation. In this paper, we demonstrate how incorporating this animation approach with an interactive volume visualization system reduces the effort in creating context-aware and coherent animations. This frees the user to focus on visualization tasks with the objective of gaining additional insight from the volume data.

  13. Book Review: Sustainable Luxury and Social Entrepreneurship. Volume II: More Stories from the Pioneers

    DEFF Research Database (Denmark)

    Skjold, Else

    2017-01-01

    volume Sustainable Luxury and Social Entrepreneurship: Stories of the Pioneers, published in 2014. The book series, as well as the awards, seeks to investigate and promote the motives, context, and practical endeavours of sustainable entrepreneurs within the premium and luxury sector....

  14. Physiological adaptation of maternal plasma volume during pregnancy: a systematic review and meta-analysis

    NARCIS (Netherlands)

    Haas, S.; Ghossein-Doha, C.; Kuijk, S.M. van; Drongelen, J. van; Spaanderman, M.E.A.

    2017-01-01

    OBJECTIVE: To describe the physiological pattern of gestational plasma volume adjustments in normal singleton pregnancy and compare this with the pattern in pregnancies complicated by pregnancy-induced hypertension, pre-eclampsia or fetal growth restriction. METHODS: We performed a meta-analysis of

  15. The short-term effect of interdisciplinary medication review on function and cost in ambulatory elderly people.

    Science.gov (United States)

    Williams, Mark E; Pulliam, Charles C; Hunter, Rebecca; Johnson, Ted M; Owens, Justine E; Kincaid, Jean; Porter, Carol; Koch, Gary

    2004-01-01

    To determine whether a medication review by a specialized team would promote regimen changes in elders taking multiple medications and to measure the effect of regimen changes on monthly cost and functioning. A randomized-controlled trial. Health center ambulatory clinic. Community-dwelling older adults taking five or more medications were assessed at baseline and 6 weeks. A medication-change intervention group of 57 elders was compared with a control group of 76 elder adults. The primary intervention was a comprehensive review and recommended modification of a patient's medication regimen. Changes were endorsed by each patient's primary physician and discussed with each patient. Measures were the Timed Manual Performance Test, Physical Performance Test, Functional Reach Assessment, subtests from the Wechsler Adult Intelligence Scale, a modified Randt Memory Test, the Center for Epidemiological Studies-Depression Scale, the Self-Rating Anxiety Scale, and the Rand 36-item Health Survey 1.0. Comorbidity was determined using the International Classification of Diseases, Ninth Revision, Clinical Modification. Medication usage was determined using brown bag review. Intervention subjects decreased their medications by an average of 1.5 drugs. No differences in functioning were observed between groups. Intervention subjects saved an average $26.92 per month in wholesale medication costs; control subjects saved $6.75 per month (P<.006). Although the intervention significantly reduced the medications taken and monthly cost, most patients were resistant to reducing medications to the recommended level. Further study is needed to understand patient resistance to reducing adverse polypharmacy and to devise better strategies for addressing this important problem in geriatric health. Greater focus on prescriber behavior is recommended.

  16. The Use of the Delphi and Other Consensus Group Methods in Medical Education Research: A Review.

    Science.gov (United States)

    Humphrey-Murto, Susan; Varpio, Lara; Wood, Timothy J; Gonsalves, Carol; Ufholz, Lee-Anne; Mascioli, Kelly; Wang, Carol; Foth, Thomas

    2017-10-01

    Consensus group methods, such as the Delphi method and nominal group technique (NGT), are used to synthesize expert opinions when evidence is lacking. Despite their extensive use, these methods are inconsistently applied. Their use in medical education research has not been well studied. The authors set out to describe the use of consensus methods in medical education research and to assess the reporting quality of these methods and results. Using scoping review methods, the authors searched the Medline, Embase, PsycInfo, PubMed, Scopus, and ERIC databases for 2009-2016. Full-text articles that focused on medical education and the keywords Delphi, RAND, NGT, or other consensus group methods were included. A standardized extraction form was used to collect article demographic data and features reflecting methodological rigor. Of the articles reviewed, 257 met the inclusion criteria. The Modified Delphi (105/257; 40.8%), Delphi (91/257; 35.4%), and NGT (23/257; 8.9%) methods were most often used. The most common study purpose was curriculum development or reform (68/257; 26.5%), assessment tool development (55/257; 21.4%), and defining competencies (43/257; 16.7%). The reporting quality varied, with 70.0% (180/257) of articles reporting a literature review, 27.2% (70/257) reporting what background information was provided to participants, 66.1% (170/257) describing the number of participants, 40.1% (103/257) reporting if private decisions were collected, 37.7% (97/257) reporting if formal feedback of group ratings was shared, and 43.2% (111/257) defining consensus a priori. Consensus methods are poorly standardized and inconsistently used in medical education research. Improved criteria for reporting are needed.

  17. Light Scattering Reviews, Vol 6 Light Scattering and Remote Sensing of Atmosphere and Surface

    CERN Document Server

    Kokhanovsky, Alexander A

    2012-01-01

    This is the next volume in series of Light Scattering Reviews. Volumes 1-5 have already been printed by Springer. The volume is composed of several papers ( usually, 10) of leading researchers in the respective field. The main focus of this book is light scattering, radiative transfer and optics of snow.

  18. Intraoperative protective mechanical ventilation for prevention of postoperative pulmonary complications: a comprehensive review of the role of tidal volume, positive end-expiratory pressure, and lung recruitment maneuvers.

    Science.gov (United States)

    Güldner, Andreas; Kiss, Thomas; Serpa Neto, Ary; Hemmes, Sabrine N T; Canet, Jaume; Spieth, Peter M; Rocco, Patricia R M; Schultz, Marcus J; Pelosi, Paolo; Gama de Abreu, Marcelo

    2015-09-01

    Postoperative pulmonary complications are associated with increased morbidity, length of hospital stay, and mortality after major surgery. Intraoperative lung-protective mechanical ventilation has the potential to reduce the incidence of postoperative pulmonary complications. This review discusses the relevant literature on definition and methods to predict the occurrence of postoperative pulmonary complication, the pathophysiology of ventilator-induced lung injury with emphasis on the noninjured lung, and protective ventilation strategies, including the respective roles of tidal volumes, positive end-expiratory pressure, and recruitment maneuvers. The authors propose an algorithm for protective intraoperative mechanical ventilation based on evidence from recent randomized controlled trials.

  19. Komplexitet för kvalitet i lärande och undervisning: bedömning av komplexa problem och studenters resonemang

    Directory of Open Access Journals (Sweden)

    Sofia Kjellström

    2011-03-01

    Full Text Available Vi utbildar studenter för att de ska ha möjlighet att lösa mycket komplexa samhällsproblem,men hur vet vi att de har utvecklat de former av tänkande och handlande som krävs? Forskning visar att vuxna tänker, talar och handlar utifrån olika nivåer av komplexitet, och att utbildning i hög grad påverkar människors förmågor. Model of Hierarchical Complexity(MHC är en teori som beskriver hur komplext information sätts samman och hur komplext personer resonerar i en fråga, vanligtvis på någon av nivåerna konkret, abstrakt, formellt, systematiskt eller metasystematisk. Syftet med denna artikel är att introducera MHC och visa på dess relevans som verktyg inom högre utbildning. Med hjälp av teorin är det möjligt att analysera både hur komplex en uppgift är och hur studenter klarar av att lösa den, vilket speglar förståelse inom ett ämne. Med modellen som mått på komplexitet tydliggörs svårighetsgraden i det som ska läras och på vilken nivå studenterna klarar att ta till sig kunskapsinnehållet. Avslutningsvis diskuteras hur studenter kan stödjas att utvecklasina förmågor till komplext resonerande och därmed skapa kvalitet i både lärande och undervisningOne of the aims of higher education is to teach students to solve complex problems, but what is the complexity of problems and the reasoning of students? The Model of Hierarchical Complexity (MHC is a theory applicable to all domains in which information is organized and accounts for increases in behavioral complexity which includes cognitive or reasoning complexity. The paper is a theoretical introduction to MHC as a tool for teaching in higher education. The model clarifies and shows the gap between the complexity in the subject and the students understanding of the same subject. We also discuss how to support the development of more complex reasoning in students.

  20. Extracorporeal treatment for theophylline poisoning: systematic review and recommendations from the EXTRIP workgroup.

    Science.gov (United States)

    Ghannoum, Marc; Wiegand, Timothy J; Liu, Kathleen D; Calello, Diane P; Godin, Melanie; Lavergne, Valery; Gosselin, Sophie; Nolin, Thomas D; Hoffman, Robert S

    2015-05-01

    The Extracorporeal Treatments in Poisoning workgroup was created to provide evidence-based recommendations on the use of extracorporeal treatments (ECTRs) in poisoning. Here, the workgroup presents its systematic review and recommendations for theophylline. After a systematic review of the literature, a subgroup reviewed articles, extracted data, summarized findings, and proposed structured voting statements following a pre-determined format. A two-round modified Delphi method was chosen to reach a consensus on voting statements and the RAND/UCLA Appropriateness Method was used to quantify disagreement. Anonymous votes were compiled, returned, and discussed. A second vote determined the final recommendations. 141 articles were included: 6 in vitro studies, 4 animal studies, 101 case reports/case series, 7 descriptive cohorts, 4 observational studies, and 19 pharmacokinetic studies, yielding a low-to-very-low quality of evidence for all recommendations. Data on 143 patients were reviewed, including 10 deaths. The workgroup concluded that theophylline is dialyzable (level of evidence = A) and made the following recommendations: ECTR is recommended in severe theophylline poisoning (1C). Specific recommendations for ECTR include a theophylline concentration [theophylline] > 100 mg/L (555 μmol/L) in acute exposure (1C), the presence of seizures (1D), life-threatening dysrhythmias (1D) or shock (1D), a rising [theophylline] despite optimal therapy (1D), and clinical deterioration despite optimal care (1D). In chronic poisoning, ECTR is suggested if [theophylline] > 60 mg/L (333 μmol/L) (2D) or if the [theophylline] > 50 mg/L (278 μmol/L) and the patient is either less than 6 months of age or older than 60 years of age (2D). ECTR is also suggested if gastrointestinal decontamination cannot be administered (2D). ECTR should be continued until clinical improvement is apparent or the [theophylline] is poisoning is amenable to ECTRs. The workgroup recommended

  1. Review of "The blood-brain and other neural barriers reviews and protocols" by Sukriti Nag (Editor

    Directory of Open Access Journals (Sweden)

    Begley David J

    2011-05-01

    Full Text Available Abstract This is a review of the content and scope of a multi-author volume for readers with an interest in the structure and function of the blood-brain barrier and in drug delivery to the central nervous system.

  2. Water SA

    African Journals Online (AJOL)

    Threats and opportunities for post-closure development in dolomitic gold mining areas of the West Rand and Far West Rand (South Africa) – a hydraulic view Part 3: Planning and uncertainty – lessons from history.

  3. 14 CFR 302.24 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... issued by the FAA. (xi) National Plan of Integrated Airport Systems (NPIAS) issued by the FAA. (xii... Coach Guide. (xxi) The Rand McNally Commercial Atlas and Marketing Guide, and the Rand McNally Road...

  4. Is orbital volume associated with eyeball and visual cortex volume in humans?

    Science.gov (United States)

    Pearce, Eiluned; Bridge, Holly

    2013-01-01

    In humans orbital volume increases linearly with absolute latitude. Scaling across mammals between visual system components suggests that these larger orbits should translate into larger eyes and visual cortices in high latitude humans. Larger eyes at high latitudes may be required to maintain adequate visual acuity and enhance visual sensitivity under lower light levels. To test the assumption that orbital volume can accurately index eyeball and visual cortex volumes specifically in humans. Structural Magnetic Resonance Imaging (MRI) techniques are employed to measure eye and orbit (n = 88) and brain and visual cortex (n = 99) volumes in living humans. Facial dimensions and foramen magnum area (a proxy for body mass) were also measured. A significant positive linear relationship was found between (i) orbital and eyeball volumes, (ii) eyeball and visual cortex grey matter volumes and (iii) different visual cortical areas, independently of overall brain volume. In humans the components of the visual system scale from orbit to eye to visual cortex volume independently of overall brain size. These findings indicate that orbit volume can index eye and visual cortex volume in humans, suggesting that larger high latitude orbits do translate into larger visual cortices.

  5. Advanced human-system interface design review guideline. General evaluation model, technical development, and guideline description

    International Nuclear Information System (INIS)

    O'Hara, J.M.

    1994-07-01

    Advanced control rooms will use advanced human-system interface (HSI) technologies that may have significant implications for plant safety in that they will affect the operator's overall role in the system, the method of information presentation, and the ways in which operators interact with the system. The U.S. Nuclear Regulatory Commission (NRC) reviews the HSI aspects of control rooms to ensure that they are designed to good human factors engineering principles and that operator performance and reliability are appropriately supported to protect public health and safety. The principal guidance available to the NRC, however, was developed more than ten years ago, well before these technological changes. Accordingly, the human factors guidance needs to be updated to serve as the basis for NRC review of these advanced designs. The purpose of this project was to develop a general approach to advanced HSI review and the human factors guidelines to support NRC safety reviews of advanced systems. This two-volume report provides the results of the project. Volume I describes the development of the Advanced HSI Design Review Guideline (DRG) including (1) its theoretical and technical foundation, (2) a general model for the review of advanced HSIs, (3) guideline development in both hard-copy and computer-based versions, and (4) the tests and evaluations performed to develop and validate the DRG. Volume I also includes a discussion of the gaps in available guidance and a methodology for addressing them. Volume 2 provides the guidelines to be used for advanced HSI review and the procedures for their use

  6. Advanced human-system interface design review guideline. General evaluation model, technical development, and guideline description

    Energy Technology Data Exchange (ETDEWEB)

    O`Hara, J.M.

    1994-07-01

    Advanced control rooms will use advanced human-system interface (HSI) technologies that may have significant implications for plant safety in that they will affect the operator`s overall role in the system, the method of information presentation, and the ways in which operators interact with the system. The U.S. Nuclear Regulatory Commission (NRC) reviews the HSI aspects of control rooms to ensure that they are designed to good human factors engineering principles and that operator performance and reliability are appropriately supported to protect public health and safety. The principal guidance available to the NRC, however, was developed more than ten years ago, well before these technological changes. Accordingly, the human factors guidance needs to be updated to serve as the basis for NRC review of these advanced designs. The purpose of this project was to develop a general approach to advanced HSI review and the human factors guidelines to support NRC safety reviews of advanced systems. This two-volume report provides the results of the project. Volume I describes the development of the Advanced HSI Design Review Guideline (DRG) including (1) its theoretical and technical foundation, (2) a general model for the review of advanced HSIs, (3) guideline development in both hard-copy and computer-based versions, and (4) the tests and evaluations performed to develop and validate the DRG. Volume I also includes a discussion of the gaps in available guidance and a methodology for addressing them. Volume 2 provides the guidelines to be used for advanced HSI review and the procedures for their use.

  7. Creative Learning Environments in Education--A Systematic Literature Review

    Science.gov (United States)

    Davies, Dan; Jindal-Snape, Divya; Collier, Chris; Digby, Rebecca; Hay, Penny; Howe, Alan

    2013-01-01

    This paper reports on a systematic review of 210 pieces of educational research, policy and professional literature relating to creative environments for learning in schools, commissioned by Learning and Teaching Scotland (LTS). Despite the volume of academic literature in this field, the team of six reviewers found comparatively few empirical…

  8. Correlation between tumor regression grade and rectal volume in neoadjuvant concurrent chemoradiotherapy for rectal cancer

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Hong Seok; Choi, Doo Ho; Park, Hee Chul; Park, Won; Yu, Jeong Il; Chung, Kwang Zoo [Dept. of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of)

    2016-09-15

    To determine whether large rectal volume on planning computed tomography (CT) results in lower tumor regression grade (TRG) after neoadjuvant concurrent chemoradiotherapy (CCRT) in rectal cancer patients. We reviewed medical records of 113 patients treated with surgery following neoadjuvant CCRT for rectal cancer between January and December 2012. Rectal volume was contoured on axial images in which gross tumor volume was included. Average axial rectal area (ARA) was defined as rectal volume divided by longitudinal tumor length. The impact of rectal volume and ARA on TRG was assessed. Average rectal volume and ARA were 11.3 mL and 2.9 cm². After completion of neoadjuvant CCRT in 113 patients, pathologic results revealed total regression (TRG 4) in 28 patients (25%), good regression (TRG 3) in 25 patients (22%), moderate regression (TRG 2) in 34 patients (30%), minor regression (TRG 1) in 24 patients (21%), and no regression (TRG0) in 2 patients (2%). No difference of rectal volume and ARA was found between each TRG groups. Linear correlation existed between rectal volume and TRG (p = 0.036) but not between ARA and TRG (p = 0.058). Rectal volume on planning CT has no significance on TRG in patients receiving neoadjuvant CCRT for rectal cancer. These results indicate that maintaining minimal rectal volume before each treatment may not be necessary.

  9. Correlation between tumor regression grade and rectal volume in neoadjuvant concurrent chemoradiotherapy for rectal cancer

    International Nuclear Information System (INIS)

    Lee, Hong Seok; Choi, Doo Ho; Park, Hee Chul; Park, Won; Yu, Jeong Il; Chung, Kwang Zoo

    2016-01-01

    To determine whether large rectal volume on planning computed tomography (CT) results in lower tumor regression grade (TRG) after neoadjuvant concurrent chemoradiotherapy (CCRT) in rectal cancer patients. We reviewed medical records of 113 patients treated with surgery following neoadjuvant CCRT for rectal cancer between January and December 2012. Rectal volume was contoured on axial images in which gross tumor volume was included. Average axial rectal area (ARA) was defined as rectal volume divided by longitudinal tumor length. The impact of rectal volume and ARA on TRG was assessed. Average rectal volume and ARA were 11.3 mL and 2.9 cm². After completion of neoadjuvant CCRT in 113 patients, pathologic results revealed total regression (TRG 4) in 28 patients (25%), good regression (TRG 3) in 25 patients (22%), moderate regression (TRG 2) in 34 patients (30%), minor regression (TRG 1) in 24 patients (21%), and no regression (TRG0) in 2 patients (2%). No difference of rectal volume and ARA was found between each TRG groups. Linear correlation existed between rectal volume and TRG (p = 0.036) but not between ARA and TRG (p = 0.058). Rectal volume on planning CT has no significance on TRG in patients receiving neoadjuvant CCRT for rectal cancer. These results indicate that maintaining minimal rectal volume before each treatment may not be necessary

  10. Mathematical models for volume rendering and neutron transport

    International Nuclear Information System (INIS)

    Max, N.

    1994-09-01

    This paper reviews several different models for light interaction with volume densities of absorbing, glowing, reflecting, or scattering material. They include absorption only, glow only, glow and absorption combined, single scattering of external illumination, and multiple scattering. The models are derived from differential equations, and illustrated on a data set representing a cloud. They are related to corresponding models in neutron transport. The multiple scattering model uses an efficient method to propagate the radiation which does not suffer from the ray effect

  11. Physiological adaptation of maternal plasma volume during pregnancy: a systematic review and meta-analysis.

    Science.gov (United States)

    de Haas, S; Ghossein-Doha, C; van Kuijk, S M J; van Drongelen, J; Spaanderman, M E A

    2017-02-01

    To describe the physiological pattern of gestational plasma volume adjustments in normal singleton pregnancy and compare this with the pattern in pregnancies complicated by pregnancy-induced hypertension, pre-eclampsia or fetal growth restriction. We performed a meta-analysis of the current literature on plasma volume adjustments during physiological and complicated pregnancies. Literature was retrieved from PubMed (NCBI) and EMBASE (Ovid) databases. Included studies reported both reference plasma volume measurements (non-pregnant, prepregnancy or postpartum) and measurements obtained during predetermined gestational ages. Mean differences bet ween the reference and pregnancy plasma volume measurements were calculated for predefined intervals of gestational age using a random-effects model described by DerSimonian and Laird. Thirty studies were included in the meta-analysis with publication dates ranging from 1934 to 2007. Plasma volume increased in the first weeks of pregnancy, with the steepest increase occurring during the second trimester. Plasma volume continued to increase in the third trimester with a pooled maximum increase of 1.13 L (95% CI, 1.07-1.19 L), an increase of 45.6% (95% CI, 43.0-48.1%) in physiological pregnancies compared with the reference value. The plasma volume expansion in gestational hypertensive and growth-restricted pregnancies was 0.80 L (95% CI, 0.59-1.02 L), an increase of 32.3% (95% CI, 23.6-41.1%) in the third trimester, a smaller increase than in physiological pregnancies (P embarazo: una revisi\\xF3n sistemática y metaanálisis RESUMEN OBJETIVO: Describir el patrón fisiológico de los cambios en el volumen del plasma gestacional en embarazos normales con feto único y compararlo con el patrón en los embarazos complicados por hipertensión gestacional, preeclampsia o restricción del crecimiento fetal. MÉTODOS: Se realizó un metaanálisis de la literatura actual sobre los cambios en el volumen de plasma durante

  12. Pyrolysis and gasification of waste: a worldwide technology and business review. Vol.1: Markets and trends; Vol. 2: Technologies and processes

    International Nuclear Information System (INIS)

    2000-01-01

    The two volume report, Pyrolysis and Gasification of Waste; a Worldwide Technology and Business Review, covers technology trends and market forces, applications and markets, market profiles by region, decision makers' preferences, and the market forecast for 1999 to 2008 in Volume I. Technologies and processes are addressed in Volume II, with technology concepts, analysis of the processes, a comparative review of selected processes examined. A directory of suppliers, process developers and licenses is provided in the appendices to Volume II. (UK)

  13. Home Health Care for California's Injured Workers: Options for Implementing a Fee Schedule.

    Science.gov (United States)

    Wynn, Barbara O; Boustead, Anne

    2015-07-15

    The California Department of Industrial Relations/Division of Worker's Compensation asked RAND to provide technical assistance in developing a fee schedule for home health services provided to injured workers. The fee schedule needs to address the full spectrum of home health services ranging from skilled nursing and therapy services to unskilled personal care or chore services that may be provided by family members. RAND researchers consulted with stakeholders in the California workers' compensation system to outline issues the fee schedule should address, reviewed home health fee schedules used by other payers, and conducted interviews with WC administrators from other jurisdictions to elicit their experiences. California stakeholders identified unskilled attendant services as most problematic in determining need and payment rates, particularly services furnished by family members. RAND researchers concentrated on fee schedule options that would result in a single fee schedule covering the full range of home health care services furnished to injured workers and made three sets of recommendations. The first set pertains to obtaining additional information that would highlight the policy issues likely to occur with the implementation of the fee schedule and alternatives for assessing an injured worker's home health care needs. Another approach conforms most closely with the Labor Code requirements. It would integrate the fee schedules used by Medicare, In-Home Health Supportive Services, and the federal Office of Workers' Compensation. The third approach would base the home health fee schedule on rules used by the federal Office of Workers' Compensation.

  14. Challenges in Accommodating Volume Change of Si Anodes for Li-Ion Batteries.

    Science.gov (United States)

    Ko, Minseong; Chae, Sujong; Cho, Jaephil

    2015-11-01

    Si has been considered as a promising alternative anode for next-generation Li-ion batteries (LIBs) because of its high theoretical energy density, relatively low working potential, and abundance in nature. However, Si anodes exhibit rapid capacity decay and an increase in the internal resistance, which are caused by the large volume changes upon Li insertion and extraction. This unfortunately limits their practical applications. Therefore, managing the total volume change remains a critical challenge for effectively alleviating the mechanical fractures and instability of solid-electrolyte-interphase products. In this regard, we review the recent progress in volume-change-accommodating Si electrodes and investigate their ingenious structures with significant improvements in the battery performance, including size-controlled materials, patterned thin films, porous structures, shape-preserving shell designs, and graphene composites. These representative approaches potentially overcome the large morphologic changes in the volume of Si anodes by securing the strain relaxation and structural integrity in the entire electrode. Finally, we propose perspectives and future challenges to realize the practical application of Si anodes in LIB systems.

  15. Naval War College Review. Volume 67, Number 3, Summer 2014

    Science.gov (United States)

    2014-01-01

    Churchill� The National Review thought it “really stupefying” that the liberal government appeared obsessed with “the Disarmament craze,” and it poured...Submarines and Underwater Warfare is focused on modern submarines and undersea warfare� However, this is not the case� Instead, it is a small coffee -table

  16. Digital marketing strategies, online reviews and hotel performance

    OpenAIRE

    Pelsmacker, De, Patrick; Tilburgh, van, Sophie; Holthof, Christian

    2018-01-01

    Abstract: We investigate to what extent digital marketing strategies (such as having a digital marketing plan, responsiveness to guest reviews, and monitoring and tracking online review information) influence hotel room occupancy and RevPar directly, and indirectly through the mediating effect of the volume and valence of online reviews they lead to, and to what extent this mechanism is different for different types of hotels in terms of star rating and independent versus chain hotels. The re...

  17. Impact of robotic technique and surgical volume on the cost of radical prostatectomy.

    Science.gov (United States)

    Hyams, Elias S; Mullins, Jeffrey K; Pierorazio, Phillip M; Partin, Alan W; Allaf, Mohamad E; Matlaga, Brian R

    2013-03-01

    Our present understanding of the effect of robotic surgery and surgical volume on the cost of radical prostatectomy (RP) is limited. Given the increasing pressures placed on healthcare resource utilization, such determinations of healthcare value are becoming increasingly important. Therefore, we performed a study to define the effect of robotic technology and surgical volume on the cost of RP. The state of Maryland mandates that all acute-care hospitals report encounter-level and hospital discharge data to the Health Service Cost Review Commission (HSCRC). The HSCRC was queried for men undergoing RP between 2008 and 2011 (the period during which robot-assisted laparoscopic radical prostatectomy [RALRP] was coded separately). High-volume hospitals were defined as >60 cases per year, and high-volume surgeons were defined as >40 cases per year. Multivariate regression analysis was performed to evaluate whether robotic technique and high surgical volume impacted the cost of RP. There were 1499 patients who underwent RALRP and 2565 who underwent radical retropubic prostatectomy (RRP) during the study period. The total cost for RALRP was higher than for RRP ($14,000 vs 10,100; Probotic surgery has come to dominate the healthcare marketplace, strategies to increase the role of high-volume providers may be needed to improve the cost-effectiveness of prostate cancer surgical therapy.

  18. Best-practices guidelines for L2PSA development and applications. Volume 1 - General

    International Nuclear Information System (INIS)

    Raimond, E.; Pichereau, F.; Durin, T.; Rahni, N.; Loeffler, H.; Roesch, O.; Lajtha, G.; Santamaria, C.S.; Dienstbier, J.; Rydl, A.; Holmberg, J.E.; Lindholm, I.; Maennistoe, I.; Pauli, E.M.; Dirksen, G.; Grindon, L.; Peers, K.; Bassi, C.; Hulqvist, G.; Parozzi, F.; Polidoro, F.; Cazzoli, E.; Vitazkova, J.; Burgazzi, L.; Brinkman, H.; Seidel, A.; Schubert, B.; Wohlstein, R.; Guentay, S.; Oury, L.; Ngatchou, C.; Siltanen, S.; Niemela, I.; Routamo, T.; Vincon, L.; Helstroem, P.

    2010-01-01

    The objective of this coordinated action was to develop best practice guidelines for the performance and application of Level 2 PSA with a view to achieve harmonisation at EU level and to allow a meaningful and practical uncertainty evaluation in a Level 2 PSA. Specific relationships with communities in charge of nuclear reactor safety (utilities, safety authorities, vendors, and research or services companies) have been established in order to define the current needs in terms of guidelines for Level 2 PSA development and application. An international workshop was organised in Hamburg, with the support of VATTENFALL, in November 2008. The Level 2 PSA experts from ASAMPSA2 project partners have proposed some guidelines for the development and application of L2PSA based on their experience, open literature, and on information available from international cooperation (EC Severe Accident network of Excellence - SARNET, IAEA standards, OECD-NEA publications and workshop). There are a large number of technical issues addressed in the guideline which are not all covered with the same level of detail in the first version of the guideline. This version was submitted for external review in November 2010 by severe accident and PSA experts (especially from SARNET and OECD-NEA members). The feedback of the external review will be dis cussed during an international open works hop planned for March 2011 and all outcomes will be taken into consideration in the final version of this guideline (June 2011). The guideline includes 3 volumes: - Volume 1 - General considerations on L2PSA. - Volume 2 - Technical recommendations for Gen II and III reactors. - Volume 3 - Specific considerations for future reactors (Gen IV). The recommendations formulated in the guideline should not be considered as 'mandatory' but should help Level 2 PSA developers to achieve high quality studies with limited time and resources. It may also help Level 2 PSA reviewers by positioning one specific study in

  19. Reviews in plasmonics 2016

    CERN Document Server

    2017-01-01

    Reviews in Plasmonics 2016, the third volume of the new book series from Springer, serves as a comprehensive collection of current trends and emerging hot topics in the field of Plasmonics and closely related disciplines. It summarizes the year’s progress in surface plasmon phenomena and its applications, with authoritative analytical reviews in sufficient detail to be attractive to professional researchers, yet also appealing to the wider audience of scientists in related disciplines of Plasmonics. Reviews in Plasmonics offers an essential source of reference material for any lab working in the Plasmonics field and related areas. All academics, bench scientists, and industry professionals wishing to take advantage of the latest and greatest in the continuously emerging field of Plasmonics will find it an invaluable resource.

  20. Reviews in plasmonics 2015

    CERN Document Server

    2016-01-01

    Reviews in Plasmonics 2015, the second volume of the new book series from Springer, serves as a comprehensive collection of current trends and emerging hot topics in the field of Plasmonics and closely related disciplines. It summarizes the year’s progress in surface plasmon phenomena and its applications, with authoritative analytical reviews in sufficient detail to be attractive to professional researchers, yet also appealing to the wider audience of scientists in related disciplines of Plasmonics. Reviews in Plasmonics offers an essential source of reference material for any lab working in the Plasmonics field and related areas. All academics, bench scientists, and industry professionals wishing to take advantage of the latest and greatest in the continuously emerging field of Plasmonics will find it an invaluable resource.

  1. Predicting Nonauditory Adverse Radiation Effects Following Radiosurgery for Vestibular Schwannoma: A Volume and Dosimetric Analysis

    International Nuclear Information System (INIS)

    Hayhurst, Caroline; Monsalves, Eric; Bernstein, Mark; Gentili, Fred; Heydarian, Mostafa; Tsao, May; Schwartz, Michael; Prooijen, Monique van; Millar, Barbara-Ann; Ménard, Cynthia; Kulkarni, Abhaya V.; Laperriere, Norm; Zadeh, Gelareh

    2012-01-01

    Purpose: To define clinical and dosimetric predictors of nonauditory adverse radiation effects after radiosurgery for vestibular schwannoma treated with a 12 Gy prescription dose. Methods: We retrospectively reviewed our experience of vestibular schwannoma patients treated between September 2005 and December 2009. Two hundred patients were treated at a 12 Gy prescription dose; 80 had complete clinical and radiological follow-up for at least 24 months (median, 28.5 months). All treatment plans were reviewed for target volume and dosimetry characteristics; gradient index; homogeneity index, defined as the maximum dose in the treatment volume divided by the prescription dose; conformity index; brainstem; and trigeminal nerve dose. All adverse radiation effects (ARE) were recorded. Because the intent of our study was to focus on the nonauditory adverse effects, hearing outcome was not evaluated in this study. Results: Twenty-seven (33.8%) patients developed ARE, 5 (6%) developed hydrocephalus, 10 (12.5%) reported new ataxia, 17 (21%) developed trigeminal dysfunction, 3 (3.75%) had facial weakness, and 1 patient developed hemifacial spasm. The development of edema within the pons was significantly associated with ARE (p = 0.001). On multivariate analysis, only target volume is a significant predictor of ARE (p = 0.001). There is a target volume threshold of 5 cm3, above which ARE are more likely. The treatment plan dosimetric characteristics are not associated with ARE, although the maximum dose to the 5th nerve is a significant predictor of trigeminal dysfunction, with a threshold of 9 Gy. The overall 2-year tumor control rate was 96%. Conclusions: Target volume is the most important predictor of adverse radiation effects, and we identified the significant treatment volume threshold to be 5 cm3. We also established through our series that the maximum tolerable dose to the 5th nerve is 9 Gy.

  2. Predicting Nonauditory Adverse Radiation Effects Following Radiosurgery for Vestibular Schwannoma: A Volume and Dosimetric Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Hayhurst, Caroline; Monsalves, Eric; Bernstein, Mark; Gentili, Fred [Gamma Knife Unit, Division of Neurosurgery, University Health Network, Toronto (Canada); Heydarian, Mostafa; Tsao, May [Radiation Medicine Program, Princess Margaret Hospital, Toronto (Canada); Schwartz, Michael [Radiation Oncology Program and Division of Neurosurgery, Sunnybrook Hospital, Toronto (Canada); Prooijen, Monique van [Radiation Medicine Program, Princess Margaret Hospital, Toronto (Canada); Millar, Barbara-Ann; Menard, Cynthia [Radiation Oncology Program, Princess Margaret Hospital, Toronto (Canada); Kulkarni, Abhaya V. [Division of Neurosurgery, Hospital for Sick Children, University of Toronto (Canada); Laperriere, Norm [Radiation Oncology Program, Princess Margaret Hospital, Toronto (Canada); Zadeh, Gelareh, E-mail: Gelareh.Zadeh@uhn.on.ca [Gamma Knife Unit, Division of Neurosurgery, University Health Network, Toronto (Canada)

    2012-04-01

    Purpose: To define clinical and dosimetric predictors of nonauditory adverse radiation effects after radiosurgery for vestibular schwannoma treated with a 12 Gy prescription dose. Methods: We retrospectively reviewed our experience of vestibular schwannoma patients treated between September 2005 and December 2009. Two hundred patients were treated at a 12 Gy prescription dose; 80 had complete clinical and radiological follow-up for at least 24 months (median, 28.5 months). All treatment plans were reviewed for target volume and dosimetry characteristics; gradient index; homogeneity index, defined as the maximum dose in the treatment volume divided by the prescription dose; conformity index; brainstem; and trigeminal nerve dose. All adverse radiation effects (ARE) were recorded. Because the intent of our study was to focus on the nonauditory adverse effects, hearing outcome was not evaluated in this study. Results: Twenty-seven (33.8%) patients developed ARE, 5 (6%) developed hydrocephalus, 10 (12.5%) reported new ataxia, 17 (21%) developed trigeminal dysfunction, 3 (3.75%) had facial weakness, and 1 patient developed hemifacial spasm. The development of edema within the pons was significantly associated with ARE (p = 0.001). On multivariate analysis, only target volume is a significant predictor of ARE (p = 0.001). There is a target volume threshold of 5 cm3, above which ARE are more likely. The treatment plan dosimetric characteristics are not associated with ARE, although the maximum dose to the 5th nerve is a significant predictor of trigeminal dysfunction, with a threshold of 9 Gy. The overall 2-year tumor control rate was 96%. Conclusions: Target volume is the most important predictor of adverse radiation effects, and we identified the significant treatment volume threshold to be 5 cm3. We also established through our series that the maximum tolerable dose to the 5th nerve is 9 Gy.

  3. [Priorization of facilitators for the implementation of medication review with follow-up service in Spanish community pharmacies through exploratory factor analysis].

    Science.gov (United States)

    Gil, Modesta Inmaculada; Benrimoj, Shalom Isaac; Martínez-Martínez, Fernando; Cardero, Manuel; Gastelurrutia, Miguel Ángel

    2013-01-01

    to prioritize previously identified in Spain facilitators for the implementation of new Pharmaceutical Services that allow designing strategies for the implementation of Medication Review with follow-up (MRFup) service. Exploratory factor analysis (EFA). A draft of a questionnaire was performed based on a previous literature review and following the RAND/UCLA methodology. An expert panel worked with it and generated a definitive questionnaire which, after piloting, was used with a representative sample of pharmacists, owners or staff members, who were working in community pharmacy, using computer-assisted telephone interviewing (CATI) methodology. To understand underlying constructs in the questionnaire an EFA was performed. Different approaches were tested such as principal components factor analysis and principal axis factoring method. The best interpretability was achieved using the Factorization of Principal axis method with Direct Oblimin rotation, which explained the 40.0% of total variance. This produced four factors defined as: «Incentives», «External campaigns», «Expert in MRFup» and «Professionalism of the pharmacist». It can be stated that for implementation and sustainability of MRFup Service it is necessary being paid; also it must be explained to health professional and society in general. Practice of MRFup service demands pharmacists receiving a more clinical education and assuming more responsibilities as health professionals. Copyright © 2012 Elsevier España, S.L. All rights reserved.

  4. Training volume and soft tissue injury in professional and non-professional rugby union players: a systematic review.

    Science.gov (United States)

    Ball, Shane; Halaki, Mark; Orr, Rhonda

    2017-07-01

    To investigate the relationship between training volume and soft tissue injury incidence, and characterise soft tissue injury in rugby union players. A systematic search of electronic databases was performed. The search strategy combined terms covering: training volume and injury, and rugby union, and players of all levels. Medline, SPORTDiscus, Web of Science, Embase, PubMed. Studies were included if they reported: male rugby union players, a clear definition of a rugby union injury, the amount of training volume undertaken by participants, and epidemiological data for soft-tissue injuries including the number or incidence. 15 studies were eligible for inclusion. Overall match and training injury incidence ranged from 3.3 to 218.0 injuries/1000 player match hours and 0.1-6.1 injuries/1000 player training hours, respectively. Muscle and tendon as well as joint (non-bone) and ligament injuries were the most frequently occurring injuries. The lower limb was the most prevalent injury location. Injury incidence was higher in professional rugby union players than non-professional players. Contact events were responsible for the greatest injury incidence. For non-contact mechanisms, running was responsible for the highest injury incidence. Inconsistent injury definitions hindered reliable comparison of injury data. The lack of reporting training volumes in hours per player per week limited the ability to investigate associations between training volume and injury incidence. A higher level of play may result in higher match injury incidence. Muscle and tendon injuries were the most common type of soft tissue injury, while the lower limb was the most common location of injury in rugby union players, and running was responsible for the highest injury incidence during non-contact events. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  5. AFRICAN JOURNAL OF ECONOMIC REVIEW

    African Journals Online (AJOL)

    Dr Kazungu

    African Journal of Economic Review, Volume IV, Issue 2, July 2016. 92. Reaching the ..... children in AIDS. Clinical AIDS identified through home- ..... 0.11. Bilharzias. 0.68 pregnancy related problems. 2.72. Dental. 0.89 intentional injury. 0.61 ..... international in collaboration with: research triangle institute (rti), the centre for.

  6. Verification and validation guidelines for high integrity systems. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Hecht, H.; Hecht, M.; Dinsmore, G.; Hecht, S.; Tang, D. [SoHaR, Inc., Beverly Hills, CA (United States)

    1995-03-01

    High integrity systems include all protective (safety and mitigation) systems for nuclear power plants, and also systems for which comparable reliability requirements exist in other fields, such as in the process industries, in air traffic control, and in patient monitoring and other medical systems. Verification aims at determining that each stage in the software development completely and correctly implements requirements that were established in a preceding phase, while validation determines that the overall performance of a computer system completely and correctly meets system requirements. Volume I of the report reviews existing classifications for high integrity systems and for the types of errors that may be encountered, and makes recommendations for verification and validation procedures, based on assumptions about the environment in which these procedures will be conducted. The final chapter of Volume I deals with a framework for standards in this field. Volume II contains appendices dealing with specific methodologies for system classification, for dependability evaluation, and for two software tools that can automate otherwise very labor intensive verification and validation activities.

  7. Verification and validation guidelines for high integrity systems. Volume 1

    International Nuclear Information System (INIS)

    Hecht, H.; Hecht, M.; Dinsmore, G.; Hecht, S.; Tang, D.

    1995-03-01

    High integrity systems include all protective (safety and mitigation) systems for nuclear power plants, and also systems for which comparable reliability requirements exist in other fields, such as in the process industries, in air traffic control, and in patient monitoring and other medical systems. Verification aims at determining that each stage in the software development completely and correctly implements requirements that were established in a preceding phase, while validation determines that the overall performance of a computer system completely and correctly meets system requirements. Volume I of the report reviews existing classifications for high integrity systems and for the types of errors that may be encountered, and makes recommendations for verification and validation procedures, based on assumptions about the environment in which these procedures will be conducted. The final chapter of Volume I deals with a framework for standards in this field. Volume II contains appendices dealing with specific methodologies for system classification, for dependability evaluation, and for two software tools that can automate otherwise very labor intensive verification and validation activities

  8. Proceedings of the 1996 U.S. DOE hydrogen program review. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-10-01

    The 29 papers contained in Volume 1 are related to systems analysis and hydrogen production. Papers in the systems analysis section discuss utility markets, comparison of hydrogen with other alternative fuels, hydrogen vehicles, renewable hydrogen production, storage, and detection, and hydrogen storage systems development. Hydrogen production methods include the use of algae, photosynthesis, glucose dehydrogenase, syngas, photoelectrochemical reactions, photovoltaics, water electrolysis, solar photochemical reactions, pyrolysis, catalytic steam reforming, municipal solid wastes, thermocatalytic cracking of natural gas, and plasma reformers. Selected papers are indexed separately for inclusion in the Energy Science and Technology Database.

  9. SINK OR SWIM? DEBT REVIEW'S AMBIVALENT "LIFELINE" ---- A SECOND SEQUEL TO "… A TALE OF TWO JUDGMENTS" NEDBANK V ANDREWS (240/2011 2011 ZAECPEHC 29 (10 May 2011; FIRSTRAND BANK LTD V EVANS 2011 4 SA 597 (KZD AND FIRSTRAND BANK LTD V JANSE VAN RENSBURG 2012 2 All SA 186 (ECP

    Directory of Open Access Journals (Sweden)

    L Steyn

    2012-11-01

    Full Text Available The interface between the National Credit Act 34 of 2005 and the Insolvency Act 24 of 1936 has been the object of our courts' attention in a number of recent cases including Ex parte Ford and Two Similar Cases 2009 3 SA 376 (WCC, Investec Bank Ltd v Mutemeri 2010 1 SA 265 (GSJ, Naidoo v ABSA Bank Ltd 2010 4 SA 597 (SCA and, more recently, Nedbank v Andrews (240/2011 2011 ZAECPEHC 29 (10 May 2011, FirstRand Bank Ltd v Evans 2011 4 597 (KZD and FirstRand Bank Ltd v Janse van Rensburg 2012 2 All SA 186 (ECP. The question raised in all of the three most recent cases was whether or not a debtor's application for debt review in terms of the National Credit Act constitutes an "act of insolvency" in terms of section 8 of the Insolvency Act, upon which a creditor may rely in an application for the compulsory sequestration of the debtor's estate. If it does, it would mean that by resorting to the debt relief measures provided by the National Credit Act a debtor commits the very act on which a creditor may base an application for a sequestration order which, if granted, will render the debtor's estate insolvent and bring about the liquidation of his assets. From the debtor's perspective, this is probably precisely the situation that he seeks to avert by applying for debt review. Further, sequestration would frustrate the stated purpose of the National Credit Act, which is that debtors should take responsibility for their debts by satisfying them in full. Concurrent creditors might also ultimately receive a dividend which falls far short of what is due to them. The question of whether a debtor's resorting to debt review may or should be the very act that triggers his estate's sequestration and its attendant consequences is an important issue, the treatment of which impacts significantly on the efficacy of the South African consumer debt relief system. This article analyses the most recent judgments and considers whether or not statutory regulation of the

  10. Correlation of ultrasound estimated placental volume and umbilical cord blood volume in term pregnancy.

    Science.gov (United States)

    Pannopnut, Papinwit; Kitporntheranunt, Maethaphan; Paritakul, Panwara; Kongsomboon, Kittipong

    2015-01-01

    To investigate the correlation between ultrasound measured placental volume and collected umbilical cord blood (UCB) volume in term pregnancy. An observational cross-sectional study of term singleton pregnant women in the labor ward at Maha Chakri Sirindhorn Medical Center was conducted. Placental thickness, height, and width were measured using two-dimensional (2D) ultrasound and calculated for placental volume using the volumetric mathematic model. After the delivery of the baby, UCB was collected and measured for its volume immediately. Then, birth weight, placental weight, and the actual placental volume were analyzed. The Pearson's correlation was used to determine the correlation between each two variables. A total of 35 pregnant women were eligible for the study. The mean and standard deviation of estimated placental volume and actual placental volume were 534±180 mL and 575±118 mL, respectively. The median UCB volume was 140 mL (range 98-220 mL). The UCB volume did not have a statistically significant correlation with the estimated placental volume (correlation coefficient 0.15; p=0.37). However, the UCB volume was significantly correlated with the actual placental volume (correlation coefficient 0.62; pcorrelation coefficient 0.38; p=0.02). The estimated placental volume by 2D ultrasound was not significantly correlated with the UCB volume. Further studies to establish the correlation between the UCB volume and the estimated placental volume using other types of placental imaging may be needed.

  11. Radiation therapy for breast cancer: Literature review

    Energy Technology Data Exchange (ETDEWEB)

    Balaji, Karunakaran, E-mail: karthik.balaji85@gmail.com [Department of Radiation Oncology, Global Hospitals, Chennai (India); School of Advanced Sciences, VIT University, Vellore (India); Subramanian, Balaji [Department of Radiation Oncology, Global Hospitals, Chennai (India); Yadav, Poonam [Department of Medical Physics and Human Oncology, University of Wisconsin-Madison, WI and Aspirus UW Cancer Center, Wisconsin Rapids, WI (United States); Anu Radha, Chandrasekaran; Ramasubramanian, Velayudham [School of Advanced Sciences, VIT University, Vellore (India)

    2016-10-01

    Concave shape with variable size target volume makes treatment planning for the breast/chest wall a challenge. Conventional techniques used for the breast/chest wall cancer treatment provided better sparing of organs at risk (OARs), with poor conformity and uniformity to the target volume. Advanced technologies such as intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) improve the target coverage at the cost of higher low dose volumes to OARs. Novel hybrid techniques present promising results in breast/chest wall irradiation in terms of target coverage as well as OARs sparing. Several published data compared these technologies for the benefit of the breast/chest wall with or without nodal volumes. The aim of this article is to review relevant data and identify the scope for further research in developing optimal treatment plan for breast/chest wall cancer treatment.

  12. Radiation therapy for breast cancer: Literature review

    International Nuclear Information System (INIS)

    Balaji, Karunakaran; Subramanian, Balaji; Yadav, Poonam; Anu Radha, Chandrasekaran; Ramasubramanian, Velayudham

    2016-01-01

    Concave shape with variable size target volume makes treatment planning for the breast/chest wall a challenge. Conventional techniques used for the breast/chest wall cancer treatment provided better sparing of organs at risk (OARs), with poor conformity and uniformity to the target volume. Advanced technologies such as intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) improve the target coverage at the cost of higher low dose volumes to OARs. Novel hybrid techniques present promising results in breast/chest wall irradiation in terms of target coverage as well as OARs sparing. Several published data compared these technologies for the benefit of the breast/chest wall with or without nodal volumes. The aim of this article is to review relevant data and identify the scope for further research in developing optimal treatment plan for breast/chest wall cancer treatment.

  13. MRI estimation of total renal volume demonstrates significant association with healthy donor weight

    International Nuclear Information System (INIS)

    Cohen, Emil I.; Kelly, Sarah A.; Edye, Michael; Mitty, Harold A.; Bromberg, Jonathan S.

    2009-01-01

    Purpose: The purpose of this study was to correlate total renal volume (TRV) calculations, obtained through the voxel-count method and ellipsoid formula with various physical characteristics. Materials and methods: MRI reports and physical examination from 210 healthy kidney donors (420 kidneys), on whom renal volumes were obtained using the voxel-count method, were retrospectively reviewed. These values along with ones obtained through a more traditional method (ellipsoid formula) were correlated with subject height, body weight, body mass index (BMI), and age. Results: TRV correlated strongly with body weight (r = 0.7) and to a lesser degree with height, age, or BMI (r = 0.5, -0.2, 0.3, respectively). The left kidney volume was greater than the right, on average (p < 0.001). The ellipsoid formula method over-estimated renal volume by 17% on average which was significant (p < 0.001). Conclusions: Body weight was the physical characteristic which demonstrated the strongest correlation with renal volume in healthy subjects. Given this finding, a formula was derived for estimating the TRV for a given patient based on the his or her weight: TRV = 2.96 x weight (kg) + 113 ± 64.

  14. ŢARA ZĂRANDULUI CA PROIECŢIE SPAŢIALĂ MENTALĂ

    OpenAIRE

    Nicoleta DAVID

    2009-01-01

    The Land of Zărand as Metal Spatial Projection.The physical support of the Zărand mental space is represented by the morphology of the region, by the forestry domain (generator of a special type of behaviour and of peculiar occupations), by the mining activity (especially the one related to the gold-bearing veins) and by the historical events that led to the heroic mythology. The stages in the development of the Land of Zărand into an open mental space took place gradually based on the transf...

  15. Respiratory Pattern and Tidal Volumes Differ for Pressure Support and Volume-assured Pressure Support in Amyotrophic Lateral Sclerosis.

    Science.gov (United States)

    Nicholson, Trevor T; Smith, Sean B; Siddique, Teepu; Sufit, Robert; Ajroud-Driss, Senda; Coleman, John M; Wolfe, Lisa F

    2017-07-01

    Amyotrophic lateral sclerosis (ALS) is a progressive neuromuscular disease resulting in respiratory failure and death. Use of noninvasive ventilation (NIV) improves survival. However, use of volume-assured pressure support (VAPS) has not been extensively studied in ALS. To explore the clinical usefulness of a detailed evaluation of device-recorded NIV data in the management of chronic respiratory failure in ALS, and to determine whether there are differences in efficacy between patients using VAPS or PS. We performed a retrospective chart review of 271 patients with ALS using either PS or VAPS, along with an evaluation of device-recorded data to explore differences in attainment of goal tidal volumes (Vt) and ratio of respiratory rate to tidal volume (f/Vt), in addition to triggering and cycling ability. Two hundred and fifteen patients were using PS, while 56 were using VAPS. There were no significant differences in demographic data, symptoms, pulmonary function, or patient compliance. Compared with VAPS, achieved Vt was significantly lower for PS while f/Vt was significantly higher. Percent spontaneous triggering was relatively preserved in both cohorts, whereas percent spontaneous cycling was considerably decreased in both. Furthermore, there was no association found between spontaneous triggering or cycling, and pulmonary function, indicating the presence of low spontaneous breath cycling or triggering ability is difficult to predict. Examination of device data for exhaled tidal volumes and f/Vt may be of use in evaluating efficacy of NIV in ALS. VAPS provides more reliable goal Vt than does PS, and is associated with decreased f/Vt. Spontaneous cycling is decreased in ALS despite preservation of triggering ability. Although a set backup rate may address decreased triggering, perhaps more importantly, setting a sufficient fixed inspiratory time would address the issue of decreased cycling.

  16. Normal frontal lobe gray matter-white matter CT volume ratio in children

    International Nuclear Information System (INIS)

    Thompson, J.R.; Engelhart, J.; Hasso, A.N.; Hinshaw, D.B. Jr.

    1985-01-01

    We attempted to establish a computed tomographic value representing the normal volume ratio of gray matter to white matter (G/W) in children in order to have a baseline for studying various developmental disorders such as white matter hypoplasia. The records of 150 children 16 years of age or younger who had normal cranial computed tomography were reviewed. From these a group of 119 were excluded for various reasons. The remaining 3 were presumed to have normal brains. Using the region of interest function for tracing gray and white matter boundaries, superior and ventral to the foramen of Munro area, measurements were determined for consecutive adjacent frontal slices. Volumes were then calculated for both gray and white matter. A volume ratio of 2.010 (sigma=0.349), G/W, was then derived from each of 31 children. The clinical value of this ratio will be determined by future investigation. (orig.)

  17. String Theory Volume 1: An Introduction to the Bosonic String and Volume 2: Superstring Theory and Beyond

    Energy Technology Data Exchange (ETDEWEB)

    Carlip, S [Department of Physics, University of California, Davis, CA 95616 (United States)

    2006-10-21

    The early 1980s, when I first learned theory, were desperate times for graduate students. We searched frantically for coherent introductions, passing tattered copies of review articles around like samizdat, struggling over obscure references to ancient models of strong interactions, and flocking to lectures-not least those by Joe Polchinski-that promised to really explain what was going on. If only this book had been around, it would have saved much grief. Volume I, The Bosonic String, offers a clear and well organized introduction to bosonic string theory. Topics range from the 'classical' (spectra, vertex operators, consistency conditions, etc.) to the 'modern' (D-branes first appear in an exercise at the end of chapter 1, noncommutative geometry shows up in chapter 8). Polchinski does not hesitate to discuss sophisticated matters-path integral measures, BRST symmetries, etc.-but his approach is pedagogical, and his writing is lucid, if sometimes a bit terse. Chapters end with problems that are sometimes difficult but never impossible. A very useful annotated bibliography directs readers to resources for further study, and a nearly 30-page glossary provides short but clear definitions of key terms. There is much here that will appeal to relativists. Polchinski uses the covariant Polyakov path integral approach to quantization from early on; he clearly distinguishes Weyl invariance from conformal invariance; he is appropriately careful about using complex coordinates on topologically nontrivial manifolds; he keeps the string world sheet metric explicit at the start instead of immediately hiding it by a gauge choice. Volume II includes an elegant introduction to anticommuting coordinates and superconformal transformations. A few conventions may cause confusion-%, Polchinski's stress-energy tensor, for instance, differs from the standard general relativistic definition by a factor of -2{pi}, and while this is briefly mentioned in the text

  18. Draft Strategic Laboratory Missions Plan. Volume II

    International Nuclear Information System (INIS)

    1996-03-01

    This volume described in detail the Department's research and technology development activities and their funding at the Department's laboratories. It includes 166 Mission Activity Profiles, organized by major mission area, with each representing a discrete budget function called a Budget and Reporting (B ampersand R) Code. The activities profiled here encompass the total research and technology development funding of the laboratories from the Department. Each profile includes a description of the activity and shows how the funding for that activity is distributed among the DOE laboratories as well as universities and industry. The profiles also indicate the principal laboratories for each activity, as well as which other laboratories are involved. The information in this volume is at the core of the Strategic Laboratory Mission Plan. It enables a reader to follow funds from the Department's appropriation to a specific activity description and to specific R ampersand D performing institutions. This information will enable the Department, along with the Laboratory Operations Board and Congress, to review the distribution of R ampersand D performers chosen to execute the Department's missions

  19. Draft Strategic Laboratory Missions Plan. Volume II

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    This volume described in detail the Department`s research and technology development activities and their funding at the Department`s laboratories. It includes 166 Mission Activity Profiles, organized by major mission area, with each representing a discrete budget function called a Budget and Reporting (B & R) Code. The activities profiled here encompass the total research and technology development funding of the laboratories from the Department. Each profile includes a description of the activity and shows how the funding for that activity is distributed among the DOE laboratories as well as universities and industry. The profiles also indicate the principal laboratories for each activity, as well as which other laboratories are involved. The information in this volume is at the core of the Strategic Laboratory Mission Plan. It enables a reader to follow funds from the Department`s appropriation to a specific activity description and to specific R & D performing institutions. This information will enable the Department, along with the Laboratory Operations Board and Congress, to review the distribution of R & D performers chosen to execute the Department`s missions.

  20. Nuclear Safety: Volume 29, No. 3: Technical progress review

    Energy Technology Data Exchange (ETDEWEB)

    Silver, E G [ed.

    1988-07-01

    Nuclear Safety is a review journal that covers significant development in the field of nuclear safety. Its scope included the analysis and control of hazards associated with nuclear energy, operations involving fissionable materials and the products of nuclear fission and their effects on the environment. Primary emphasis is on safety in reactor design, construction, and operation; however, the safety aspects of the entire fuel cycle, including fuel fabrication, spent-fuel processing, nuclear waste disposal, handling of radioisotopes, and environmental effects of these operations, are also treated. Individual papers have been cataloged separately.

  1. Military Review. Volume 87, Number 3, May-June 2007

    Science.gov (United States)

    2007-06-01

    Urban management 1,839 54% 28% 18% Pillar 1: Human and Social Protection 6,896 1.1 Refugee return 155 1.2 Education 2,703 1.3 Health and nutrition ...in the Sudan immediately after Boutros’s release from GoS captivity in April 2002. co ur te sy o f a ut ho r 51Military review  May-June 2007 P E A...irregular roles. Operation Blue Bird was a prototypical special operation that aimed to exploit the ancient enmity between the northern Kabyle tribe and

  2. Wellness Programs and Means of Getting Employees to Stay Healthy: A Response to Kristin Van Busum and Soeren Mattke

    Directory of Open Access Journals (Sweden)

    Bahaudin G. Mujtaba

    2014-01-01

    Full Text Available This is a short writing in response to the “Financial Incentives: Only One Piece of the Workplace Wellness Puzzle” (1 by Kristin Van Busum and Soeren Mattke of the RAND Health Advisory Services, RAND Corporation, in Boston.

  3. Note of appreciation to reviewers.

    Science.gov (United States)

    Reichert, Janice M

    2014-01-01

    As we begin a new year, the Editorial Board, Associate and Assistant Editors and Editor-in-Chief of mAbs would like to thank the reviewers who contributed their insights and advice, as well as suggestions for improvement of manuscripts submitted for publication in mAbs volume 5, issues 1-6 (2013). The peer-review process involved the investment of substantial time and effort by the experts listed below, and we sincerely appreciate their valuable input on the selection of relevant, high-quality articles for mAbs readers.

  4. Annual review in automatic programming

    CERN Document Server

    Goodman, Richard

    2014-01-01

    Annual Review in Automatic Programming, Volume 4 is a collection of papers that deals with the GIER ALGOL compiler, a parameterized compiler based on mechanical linguistics, and the JOVIAL language. A couple of papers describes a commercial use of stacks, an IBM system, and what an ideal computer program support system should be. One paper reviews the system of compilation, the development of a more advanced language, programming techniques, machine independence, and program transfer to other machines. Another paper describes the ALGOL 60 system for the GIER machine including running ALGOL pro

  5. Chemical Safety Vulnerability Working Group report. Volume 2

    International Nuclear Information System (INIS)

    1994-09-01

    The Chemical Safety Vulnerability (CSV) Working Group was established to identify adverse conditions involving hazardous chemicals at DOE facilities that might result in fires or explosions, release of hazardous chemicals to the environment, or exposure of workers or the public to chemicals. A CSV Review was conducted in 148 facilities at 29 sites. Eight generic vulnerabilities were documented related to: abandoned chemicals and chemical residuals; past chemical spills and ground releases; characterization of legacy chemicals and wastes; disposition of legacy chemicals; storage facilities and conditions; condition of facilities and support systems; unanalyzed and unaddressed hazards; and inventory control and tracking. Weaknesses in five programmatic areas were also identified related to: management commitment and planning; chemical safety management programs; aging facilities that continue to operate; nonoperating facilities awaiting deactivation; and resource allocations. Volume 2 consists of seven appendices containing the following: Tasking memorandums; Project plan for the CSV Review; Field verification guide for the CSV Review; Field verification report, Lawrence Livermore National Lab.; Field verification report, Oak Ridge Reservation; Field verification report, Savannah River Site; and the Field verification report, Hanford Site

  6. Chemical Safety Vulnerability Working Group report. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    1994-09-01

    The Chemical Safety Vulnerability (CSV) Working Group was established to identify adverse conditions involving hazardous chemicals at DOE facilities that might result in fires or explosions, release of hazardous chemicals to the environment, or exposure of workers or the public to chemicals. A CSV Review was conducted in 148 facilities at 29 sites. Eight generic vulnerabilities were documented related to: abandoned chemicals and chemical residuals; past chemical spills and ground releases; characterization of legacy chemicals and wastes; disposition of legacy chemicals; storage facilities and conditions; condition of facilities and support systems; unanalyzed and unaddressed hazards; and inventory control and tracking. Weaknesses in five programmatic areas were also identified related to: management commitment and planning; chemical safety management programs; aging facilities that continue to operate; nonoperating facilities awaiting deactivation; and resource allocations. Volume 2 consists of seven appendices containing the following: Tasking memorandums; Project plan for the CSV Review; Field verification guide for the CSV Review; Field verification report, Lawrence Livermore National Lab.; Field verification report, Oak Ridge Reservation; Field verification report, Savannah River Site; and the Field verification report, Hanford Site.

  7. Inertial Fusion Energy reactor design studies: Prometheus-L, Prometheus-H. Volume 2, Final report

    Energy Technology Data Exchange (ETDEWEB)

    Waganer, L.M.; Driemeyer, D.E.; Lee, V.D.

    1992-03-01

    This report contains a review of design studies for Inertial Confinement reactor. This second of three volumes discussions is some detail the following: Objectives, requirements, and assumptions; rationale for design option selection; key technical issues and R&D requirements; and conceptual design selection and description.

  8. AFRICAN JOURNAL OF ECONOMIC REVIEW

    African Journals Online (AJOL)

    Dr Kazungu

    African Journal of Economic Review, Volume IV, Issue 1, January 2016 ... infant mortality rates in 31 selected sub-Saharan African countries for the .... Also, declines in nutritional status as a result of upsurge in food prices may cause poor birth ..... Deaton, A. (1989) 'Rice Prices and Income Distribution in Thailand: A Non- ...

  9. LLE Review

    Energy Technology Data Exchange (ETDEWEB)

    Keck, R.L. (ed.)

    1992-01-01

    This volume of the LLE Review, covering the period January--March 1992, contains articles on the use of diffraction gratings in laser applications, and the fabrication of gratings for use in these applications. there are two articles on the use of lasers to explore fundamental physics issues and an article on the use of a solid-state diode array for x-ray imaging. Finally, the activities of the National Laser Users Facility and the GDL and OMEGA laser systems are summarized.

  10. Organizational analysis and safety for utilities with nuclear power plants: an organizational overview. Volume 1

    International Nuclear Information System (INIS)

    Osborn, R.N.; Olson, J.; Sommers, P.E.; McLaughlin, S.D.; Jackson, M.S.; Scott, W.G.; Connor, P.E.

    1983-08-01

    This two-volume report presents the results of initial research on the feasibility of applying organizational factors in nuclear power plant (NPP) safety assessment. A model is introduced for the purposes of organizing the literature review and showing key relationships among identified organizational factors and nuclear power plant safety. Volume I of this report contains an overview of the literature, a discussion of available safety indicators, and a series of recommendations for more systematically incorporating organizational analysis into investigations of nuclear power plant safety

  11. Tumor Volume-Adapted Dosing in Stereotactic Ablative Radiotherapy of Lung Tumors

    Energy Technology Data Exchange (ETDEWEB)

    Trakul, Nicholas; Chang, Christine N.; Harris, Jeremy [Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA (United States); Chapman, Christopher [Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA (United States); University of Michigan School of Medicine, Ann Arbor, MI (United States); Rao, Aarti [Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA (United States); University of California, Davis, School of Medicine, Davis, CA (United States); Shen, John [Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA (United States); University of California, Irvine, School of Medicine, Irvine, CA (United States); Quinlan-Davidson, Sean [Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA (United States); Department of Radiation Oncology, McMaster University, Juravinski Cancer Centre, Hamilton, Ontario (Canada); Filion, Edith J. [Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA (United States); Departement de Medecine, Service de Radio-Oncologie, Centre Hospitalier de l' Universite de Montreal, Montreal, Quebec (Canada); Wakelee, Heather A.; Colevas, A. Dimitrios [Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford, CA (United States); Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA (United States); Whyte, Richard I. [Department of Cardiothoracic Surgery, Division of General Thoracic Surgery, Stanford University School of Medicine, Stanford, CA (United States); Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA (United States); and others

    2012-09-01

    Purpose: Current stereotactic ablative radiotherapy (SABR) protocols for lung tumors prescribe a uniform dose regimen irrespective of tumor size. We report the outcomes of a lung tumor volume-adapted SABR dosing strategy. Methods and Materials: We retrospectively reviewed the outcomes in 111 patients with a total of 138 primary or metastatic lung tumors treated by SABR, including local control, regional control, distant metastasis, overall survival, and treatment toxicity. We also performed subset analysis on 83 patients with 97 tumors treated with a volume-adapted dosing strategy in which small tumors (gross tumor volume <12 mL) received single-fraction regimens with biologically effective doses (BED) <100 Gy (total dose, 18-25 Gy) (Group 1), and larger tumors (gross tumor volume {>=}12 mL) received multifraction regimens with BED {>=}100 Gy (total dose, 50-60 Gy in three to four fractions) (Group 2). Results: The median follow-up time was 13.5 months. Local control for Groups 1 and 2 was 91.4% and 92.5%, respectively (p = 0.24) at 12 months. For primary lung tumors only (excluding metastases), local control was 92.6% and 91.7%, respectively (p = 0.58). Regional control, freedom from distant metastasis, and overall survival did not differ significantly between Groups 1 and 2. Rates of radiation pneumonitis, chest wall toxicity, and esophagitis were low in both groups, but all Grade 3 toxicities developed in Group 2 (p = 0.02). Conclusion: A volume-adapted dosing approach for SABR of lung tumors seems to provide excellent local control for both small- and large-volume tumors and may reduce toxicity.

  12. SU-E-T-148: Benchmarks and Pre-Treatment Reviews: A Study of Quality Assurance Effectiveness

    International Nuclear Information System (INIS)

    Lowenstein, J; Nguyen, H; Roll, J; Walsh, A; Tailor, A; Followill, D

    2015-01-01

    Purpose: To determine the impact benchmarks and pre-treatment reviews have on improving the quality of submitted clinical trial data. Methods: Benchmarks are used to evaluate a site’s ability to develop a treatment that meets a specific protocol’s treatment guidelines prior to placing their first patient on the protocol. A pre-treatment review is an actual patient placed on the protocol in which the dosimetry and contour volumes are evaluated to be per protocol guidelines prior to allowing the beginning of the treatment. A key component of these QA mechanisms is that sites are provided timely feedback to educate them on how to plan per the protocol and prevent protocol deviations on patients accrued to a protocol. For both benchmarks and pre-treatment reviews a dose volume analysis (DVA) was performed using MIM softwareTM. For pre-treatment reviews a volume contour evaluation was also performed. Results: IROC Houston performed a QA effectiveness analysis of a protocol which required both benchmarks and pre-treatment reviews. In 70 percent of the patient cases submitted, the benchmark played an effective role in assuring that the pre-treatment review of the cases met protocol requirements. The 35 percent of sites failing the benchmark subsequently modified there planning technique to pass the benchmark before being allowed to submit a patient for pre-treatment review. However, in 30 percent of the submitted cases the pre-treatment review failed where the majority (71 percent) failed the DVA. 20 percent of sites submitting patients failed to correct their dose volume discrepancies indicated by the benchmark case. Conclusion: Benchmark cases and pre-treatment reviews can be an effective QA tool to educate sites on protocol guidelines and to minimize deviations. Without the benchmark cases it is possible that 65 percent of the cases undergoing a pre-treatment review would have failed to meet the protocols requirements.Support: U24-CA-180803

  13. Bare-Hand Volume Cracker for Raw Volume Data Analysis

    Directory of Open Access Journals (Sweden)

    Bireswar Laha

    2016-09-01

    Full Text Available Analysis of raw volume data generated from different scanning technologies faces a variety of challenges, related to search, pattern recognition, spatial understanding, quantitative estimation, and shape description. In a previous study, we found that the Volume Cracker (VC 3D interaction (3DI technique mitigated some of these problems, but this result was from a tethered glove-based system with users analyzing simulated data. Here, we redesigned the VC by using untethered bare-hand interaction with real volume datasets, with a broader aim of adoption of this technique in research labs. We developed symmetric and asymmetric interfaces for the Bare-Hand Volume Cracker (BHVC through design iterations with a biomechanics scientist. We evaluated our asymmetric BHVC technique against standard 2D and widely used 3D interaction techniques with experts analyzing scanned beetle datasets. We found that our BHVC design significantly outperformed the other two techniques. This study contributes a practical 3DI design for scientists, documents lessons learned while redesigning for bare-hand trackers, and provides evidence suggesting that 3D interaction could improve volume data analysis for a variety of visual analysis tasks. Our contribution is in the realm of 3D user interfaces tightly integrated with visualization, for improving the effectiveness of visual analysis of volume datasets. Based on our experience, we also provide some insights into hardware-agnostic principles for design of effective interaction techniques.

  14. Volume Regulated Channels

    DEFF Research Database (Denmark)

    Klausen, Thomas Kjær

    of volume perturbations evolution have developed system of channels and transporters to tightly control volume homeostasis. In the past decades evidence has been mounting, that the importance of these volume regulated channels and transporters are not restricted to the defense of cellular volume...... but are also essential for a number of physiological processes such as proliferation, controlled cell death, migration and endocrinology. The thesis have been focusing on two Channels, namely the swelling activated Cl- channel (ICl, swell) and the transient receptor potential Vanilloid (TRPV4) channel. I: Cl......- serves a multitude of functions in the mammalian cell, regulating the membrane potential (Em), cell volume, protein activity and the driving force for facilitated transporters giving Cl- and Cl- channels a major potential of regulating cellular function. These functions include control of the cell cycle...

  15. Naval War College Review. Volume 68, Number 3, Summer 2015

    Science.gov (United States)

    2015-01-01

    158 Hotel Florida: Truth, Love, and Death in the Spanish Civil War, by Amanda Vaill reviewed by Jeffrey M. Shaw...Administrative Service of the Ministry of Customs —are being united to form a unified maritime law-enforcement agency, the China Coast Guard, with a...and organizations, mentoring is consistently associated with greater work satisfaction and perfor- mance, higher retention, better physical health

  16. Making literature reviews more reliable through application of lessons from systematic reviews.

    Science.gov (United States)

    Haddaway, N R; Woodcock, P; Macura, B; Collins, A

    2015-12-01

    Review articles can provide valuable summaries of the ever-increasing volume of primary research in conservation biology. Where findings may influence important resource-allocation decisions in policy or practice, there is a need for a high degree of reliability when reviewing evidence. However, traditional literature reviews are susceptible to a number of biases during the identification, selection, and synthesis of included studies (e.g., publication bias, selection bias, and vote counting). Systematic reviews, pioneered in medicine and translated into conservation in 2006, address these issues through a strict methodology that aims to maximize transparency, objectivity, and repeatability. Systematic reviews will always be the gold standard for reliable synthesis of evidence. However, traditional literature reviews remain popular and will continue to be valuable where systematic reviews are not feasible. Where traditional reviews are used, lessons can be taken from systematic reviews and applied to traditional reviews in order to increase their reliability. Certain key aspects of systematic review methods that can be used in a context-specific manner in traditional reviews include focusing on mitigating bias; increasing transparency, consistency, and objectivity, and critically appraising the evidence and avoiding vote counting. In situations where conducting a full systematic review is not feasible, the proposed approach to reviewing evidence in a more systematic way can substantially improve the reliability of review findings, providing a time- and resource-efficient means of maximizing the value of traditional reviews. These methods are aimed particularly at those conducting literature reviews where systematic review is not feasible, for example, for graduate students, single reviewers, or small organizations. © 2015 Society for Conservation Biology.

  17. Future proton and electron colliders: Dreams for the 1990's

    International Nuclear Information System (INIS)

    Richter, B.

    1988-10-01

    In this paper I have reviewed the possibilities for new colliders that might be available in the 1990's. One or more new proton should be available in the late-90s based on plans of Europe, the US and the USSR. The two very high energy machines, LHC and SSC, are quite expensive, and their construction will be more decided by the politicians' view on the availability of resources than by the physicists' view of the need for new machines. Certainly something will be built, but the question is when. New electron colliders beyond LEP II could be available in the late 1990's as well. Most of the people who have looked at this problem believe that at a minimum three years of RandD are required before a proposal can be made, two years will be required to convince the authorities to go ahead, and five years will be required to build such a machine. Thus the earliest time a new electron collider at high energy could be available is around 1988. A strong international RandD program will be required to meet that schedule. In the field of B factories, PSI's proposal is the first serious step beyond the capabilities of CESR. There are other promising techniques but these need more RandD. The least RandD would be required for the asymmetric storage ring systems, while the most would be required for high luminosity linear colliders. For the next decade, high energy physics will be doing its work at the high energy frontier with Tevatron I and II, UNK, SLC, LEP I and II, and HERA. The opportunities for science presented by experiments at these facilities are very great, and it is to be hoped that the pressure for funding to construct the next generation facilities will not badly affect the operating budgets of the ones we now have or which will soon be turning on. 9 refs., 12 figs., 6 tabs

  18. Book review Information and Communication Technologies for ...

    African Journals Online (AJOL)

    Book review. Information and Communication Technologies for Development in Africa: Volume 2. The Experience with Community Telecentres By Florence Etta and Sheila Parvyn-Wamahiu (2003). Kibet A Ngetich. Abstract. No Abstract Available Africa Development Vol. XXX (1&2) 2005: 254-256.

  19. Volume-Dependent Overestimation of Spontaneous Intracerebral Hematoma Volume by the ABC/2 Formula

    International Nuclear Information System (INIS)

    Chih-Wei Wang; Chun-Jung Juan; Hsian-He Hsu; Hua-Shan Liu; Cheng-Yu Chen; Chun-Jen Hsueh; Hung-Wen Kao; Guo-Shu Huang; Yi-Jui Liu; Chung-Ping Lo

    2009-01-01

    Background: Although the ABC/2 formula has been widely used to estimate the volume of intracerebral hematoma (ICH), the formula tends to overestimate hematoma volume. The volume-related imprecision of the ABC/2 formula has not been documented quantitatively. Purpose: To investigate the volume-dependent overestimation of the ABC/2 formula by comparing it with computer-assisted volumetric analysis (CAVA). Material and Methods: Forty patients who had suffered spontaneous ICH and who had undergone non-enhanced brain computed tomography scans were enrolled in this study. The ICH volume was estimated based on the ABC/2 formula and also calculated by CAVA. Based on the ICH volume calculated by the CAVA method, the patients were divided into three groups: group 1 consisted of 17 patients with an ICH volume of less than 20 ml; group 2 comprised 13 patients with an ICH volume of 20 to 40 ml; and group 3 was composed of 10 patients with an ICH volume larger than 40 ml. Results: The mean estimated hematoma volume was 43.6 ml when using the ABC/2 formula, compared with 33.8 ml when using the CAVA method. The mean estimated difference was 1.3 ml, 4.4 ml, and 31.4 ml for groups 1, 2, and 3, respectively, corresponding to an estimation error of 9.9%, 16.7%, and 37.1% by the ABC/2 formula (P<0.05). Conclusion: The ABC/2 formula significantly overestimates the volume of ICH. A positive association between the estimation error and the volume of ICH is demonstrated

  20. Association between tumour volume and recurrence of squamous cell carcinoma of the head and neck

    International Nuclear Information System (INIS)

    Kazmi, F.N.; Adil, A.; Ghaffar, S.; Ahmed, F.

    2012-01-01

    Objective: To evaluate the prognostic significance of computerized tomography derived tumour volume for squamous cell cancers of the head and neck, treated primarily by surgery. Methods: The retrospective review study comprised 72 patients with head and neck malignancies who were treated primarily by surgery at Aga Khan University Hospital, Karachi, with/without adjuvant. It was done from May 2007 to November 2008. Each patient was followed up for a minimum of one year to check for recurrence. For statistical analysis SPSS 17 was used. Frequencies, cross-tabulations with chi square tests to find associations, binary logistic regression analysis, Cox regression analysis and receiver operating characteristic curve tests were run on the data. Results: Overall, the median tumour volume for patients with recurrent disease was 52 cm/sup 3/ compared to 22 cm/sup 3/ for those who did not have a recurrence. It was found that large tumour volume was associated with a significantly higher chance of recurrence (p = 0.009). Laryngeal cancers with volumes greater than 46 cm/sup 3/ and oral cancers with volumes greater than 23.1 cm/sup 3/ were associated with poor prognosis. Conclusions: The primary tumour volume can represent an important prognostic factor for treatment outcome. Patients with larger primary tumour volumes should be treated more aggressively. (author)

  1. The Future Of Sectarian Relations in the Middle East

    Science.gov (United States)

    2017-01-01

    by demanding remuneration for its forward deployments. Meanwhile, the United States relationship with the United Arab Emirates and Qatar is growing...information on the RAND Intelligence Policy Center, see http://www.rand.org/nsrd/ndri/centers/intel.html or contact the director (contact

  2. Environmental epidemiology, Volume 1: Public health and hazardous wastes

    International Nuclear Information System (INIS)

    Anon.

    1991-01-01

    Environmental Epidemiology, Volume 1, represents the first of several planned volumes on the uses of epidemiologic techniques to study environmental public health issues. This text focuses on environmental epidemiology as it relates to hazardous waste in the United States. This study was commissioned by the Agency for Toxic Substances and Disease Registry to examine available data for evidence of adverse health effects on human populations exposed to hazardous waste. The committee was also asked to identify data gaps which were impediments to analyzing hazardous waste health effects and to suggest ways that such environmental health assessments might be improved. The committee's solution to the paucity of data on this issue was to concentrate in this volume on identifying the available, peer-reviewed data and, consequently, the major data gaps. The study opens with a recapitulation of the context of hazardous waste sites in the United States, the approaches currently used by state and federal epidemiologists in analyzing hazardous waste exposure and effects, and candid assessment of the problems associated with environmental exposure assessment. From that context, the committee then presents the data currently available to assess human exposures through air, domestic water consumption, soil, and the food chain. The general focus here is on biomarker data as the date of choice. As with all NAS reports, this one closes with general conclusions and recommendations. Environmental health risk assessors will find this volume a valuable resource

  3. Do new anesthesia ventilators deliver small tidal volumes accurately during volume-controlled ventilation?

    Science.gov (United States)

    Bachiller, Patricia R; McDonough, Joseph M; Feldman, Jeffrey M

    2008-05-01

    During mechanical ventilation of infants and neonates, small changes in tidal volume may lead to hypo- or hyperventilation, barotrauma, or volutrauma. Partly because breathing circuit compliance and fresh gas flow affect tidal volume delivery by traditional anesthesia ventilators in volume-controlled ventilation (VCV) mode, pressure-controlled ventilation (PCV) using a circle breathing system has become a common approach to minimizing the risk of mechanical ventilation for small patients, although delivered tidal volume is not assured during PCV. A new generation of anesthesia machine ventilators addresses the problems of VCV by adjusting for fresh gas flow and for the compliance of the breathing circuit. In this study, we evaluated the accuracy of new anesthesia ventilators to deliver small tidal volumes. Four anesthesia ventilator systems were evaluated to determine the accuracy of volume delivery to the airway during VCV at tidal volume settings of 100, 200, and 500 mL under different conditions of breathing circuit compliance (fully extended and fully contracted circuits) and lung compliance. A mechanical test lung (adult and infant) was used to simulate lung compliances ranging from 0.0025 to 0.03 L/cm H(2)O. Volumes and pressures were measured using a calibrated screen pneumotachograph and custom software. We tested the Smartvent 7900, Avance, and Aisys anesthesia ventilator systems (GE Healthcare, Madison, WI) and the Apollo anesthesia ventilator (Draeger Medical, Telford, PA). The Smartvent 7900 and Avance ventilators use inspiratory flow sensors to control the volume delivered, whereas the Aisys and Apollo ventilators compensate for the compliance of the circuit. We found that the anesthesia ventilators that use compliance compensation (Aisys and Apollo) accurately delivered both large and small tidal volumes to the airway of the test lung under conditions of normal and low lung compliance during VCV (ranging from 95.5% to 106.2% of the set tidal volume

  4. Proceedings of the 21st DOE/NRC nuclear air cleaning conference; Volume 2, Sessions 9--16

    Energy Technology Data Exchange (ETDEWEB)

    First, M.W. [ed.] [Harvard Univ., Boston, MA (United States). Harvard Air Cleaning Lab.

    1991-02-01

    The 21st meeting of the Department of Energy/Nuclear Regulatory Commission (DOE/NRC) Nuclear Air Cleaning Conference was held in San Diego, CA on August 13--16, 1990. The proceedings have been published as a two volume set. Volume 2 contains sessions covering adsorbents, nuclear codes and standards, modelling, filters, safety, containment venting and a review of nuclear air cleaning programs around the world. Also included is the list of attendees and an index of authors and speakers. (MHB)

  5. Physical Review: a family of journals

    Science.gov (United States)

    Sprouse, Gene

    2013-03-01

    The expansion of research in physics in the last 100 years has been reflected in the expansion of the Physical Review(PR). Reviews of Modern Physics was the first ``new'' journal, starting in 1929. Physical Review Letters commenced in 1958, and was the first ``letters'' type of journal for important new results in all fields. By 1970 the Physical Review itself had grown so large that it was necessary to separate it by field into manageable volumes: PRA, PRB, PRC and PRD, and subsequently PRE, which was split off from PRA. More recently, two Special Topics journals for accelerator physics and physics education were pioneers of the open access business model, and the newest member of the family, Physical Review X, continues this trend. PRX is broad scope and very selective, setting it well above many of the new open access journals with a review standard of ``not incorrect.'' Some possible future directions for the Physical Review journals will be discussed.

  6. Y-12 Plant remedial action Technology Logic Diagram: Volume 3, Technology evaluation data sheets: Part A, Remedial action

    International Nuclear Information System (INIS)

    1994-09-01

    The Y-12 Plant Remedial Action Technology Logic Diagram (TLD) was developed to provide a decision-support tool that relates environmental restoration (ER) problems at the Y-12 Plant to potential technologies that can remediate these problems. The TLD identifies the research, development, demonstration, testing, and evaluation needed for sufficient development of these technologies to allow for technology transfer and application to remedial action (RA) activities. The TLD consists of three volumes. Volume 1 contains an overview of the TLD, an explanation of the program-specific responsibilities, a review of identified technologies, and the rankings of remedial technologies. Volume 2 contains the logic linkages among environmental management goals, environmental problems and the various technologies that have the potential to solve these problems. Volume 3 contains the TLD data sheets. This report is Part A of Volume 3 and contains the Remedial Action section

  7. Y-12 Plant remedial action Technology Logic Diagram: Volume 3, Technology evaluation data sheets: Part A, Remedial action

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-09-01

    The Y-12 Plant Remedial Action Technology Logic Diagram (TLD) was developed to provide a decision-support tool that relates environmental restoration (ER) problems at the Y-12 Plant to potential technologies that can remediate these problems. The TLD identifies the research, development, demonstration, testing, and evaluation needed for sufficient development of these technologies to allow for technology transfer and application to remedial action (RA) activities. The TLD consists of three volumes. Volume 1 contains an overview of the TLD, an explanation of the program-specific responsibilities, a review of identified technologies, and the rankings of remedial technologies. Volume 2 contains the logic linkages among environmental management goals, environmental problems and the various technologies that have the potential to solve these problems. Volume 3 contains the TLD data sheets. This report is Part A of Volume 3 and contains the Remedial Action section.

  8. Target volume definition with 18F-FDG PET-CT in radiotherapy treatment planning

    International Nuclear Information System (INIS)

    Carson, K. J.; Hanna, G. G.; Hounsell, A. R.

    2011-01-01

    There is considerable interest in using 18F -Fluorodeoxyglucose (FDG) positron emission tomography (PET) images for radiotherapy treatment planning (RTF) purposes, and in particular for defining target volumes. This is a rapidly evolving subject and this review describes the background to this application of PET imaging and discusses the issues involved. (authors)

  9. Feasibility of large volume casting cementation process for intermediate level radioactive waste

    International Nuclear Information System (INIS)

    Chen Zhuying; Chen Baisong; Zeng Jishu; Yu Chengze

    1988-01-01

    The recent tendency of radioactive waste treatment and disposal both in China and abroad is reviewed. The feasibility of the large volume casting cementation process for treating and disposing the intermediate level radioactive waste from spent fuel reprocessing plant in shallow land is assessed on the basis of the analyses of the experimental results (such as formulation study, solidified radioactive waste properties measurement ect.). It can be concluded large volume casting cementation process is a promising, safe and economic process. It is feasible to dispose the intermediate level radioactive waste from reprocessing plant it the disposal site chosen has resonable geological and geographical conditions and some additional effective protection means are taken

  10. Deviations in expected price impact for small transaction volumes under fee restructuring

    Science.gov (United States)

    Harvey, M.; Hendricks, D.; Gebbie, T.; Wilcox, D.

    2017-04-01

    We report on the occurrence of an anomaly in the price impacts of small transaction volumes following a change in the fee structure of an electronic market. We first review evidence for the existence of a master curve for price impact on the Johannesburg Stock Exchange (JSE). On attempting to re-estimate a master curve after fee reductions, it is found that the price impact corresponding to smaller volume trades is greater than expected relative to prior estimates for a range of listed stocks. We show that a master curve for price impact can be found following rescaling by an appropriate liquidity proxy, providing a means for practitioners to approximate price impact curves without onerous processing of tick data.

  11. Organizational analysis and safety for utilities with nuclear power plants: perspectives for organizational assessment. Volume 2

    International Nuclear Information System (INIS)

    Osborn, R.N.; Olson, J.; Sommers, P.E.

    1983-08-01

    This two-volume report presents the results of initial research on the feasibility of applying organizational factors in nuclear power plant (NPP) safety assessment. Volume 1 of this report contains an overview of the literature, a discussion of available safety indicators, and a series of recommendations for more systematically incorporating organizational analysis into investigations of nuclear power plant safety. The six chapters of this volume discuss the major elements in our general approach to safety in the nuclear industry. The chapters include information on organizational design and safety; organizational governance; utility environment and safety related outcomes; assessments by selected federal agencies; review of data sources in the nuclear power industry; and existing safety indicators

  12. Defense Acquisition Review Journal. Volume 16, Number 3, Issue 52

    Science.gov (United States)

    2009-10-01

    Journal (ARJ) print year. FROM THE EDITOR I am excited to announce the lineup of research articles for Issue 52 of the Defense Acquisition Review... identification and causality, and to prevent the variety generated by EA from reducing total product performance. From Amorphous to Defined: Balancing Risks...possible in this environment, and will allow better flow of strategic-level acquisition advice, including the identification of existing and

  13. Redefining the Practice of Peer Review Through Intelligent Automation Part 2: Data-Driven Peer Review Selection and Assignment.

    Science.gov (United States)

    Reiner, Bruce I

    2017-12-01

    In conventional radiology peer review practice, a small number of exams (routinely 5% of the total volume) is randomly selected, which may significantly underestimate the true error rate within a given radiology practice. An alternative and preferable approach would be to create a data-driven model which mathematically quantifies a peer review risk score for each individual exam and uses this data to identify high risk exams and readers, and selectively target these exams for peer review. An analogous model can also be created to assist in the assignment of these peer review cases in keeping with specific priorities of the service provider. An additional option to enhance the peer review process would be to assign the peer review cases in a truly blinded fashion. In addition to eliminating traditional peer review bias, this approach has the potential to better define exam-specific standard of care, particularly when multiple readers participate in the peer review process.

  14. Sensemaking: A Structure for an Intelligence Revolution

    Science.gov (United States)

    2011-03-01

    is Assessing the Tradecraft of Intelligence Analysis (with C. Bryan Gabbard ), TR-293 (Santa Monica, CA: RAND Corporation, 2008). xiii COMMENTARY...Gregory F. and C. Bryan Gabbard . Assessing the Tradecraft of Intelligence Analysis. TR-293. Santa Monica, CA: RAND Corporation, 2008. Tsouras, Peter G

  15. Office of Technology Development's Research, Development, Demonstration, Testing and Evaluation Mid-Year Program Review. Volume 2

    International Nuclear Information System (INIS)

    1994-01-01

    This document, Volume 2, presents brief summaries of programs being investigated at USDOE sites for waste processing, remedial action, underground storage tank remediation, and robotic applications in waste management

  16. Volume doubling time and growth rate of renal cell carcinoma determined by helical CT: a single-institution experience

    International Nuclear Information System (INIS)

    Lee, Ji Young; Kim, Chan Kyo; Choi, Dongil; Park, Byung Kwan

    2008-01-01

    The purpose of this study was to retrospectively evaluate the volume doubling time (VDT) and growth rate of renal cell carcinomas (RCC) on a serial computed tomography (CT) scan. Thirty pathologically proven RCCs were reviewed with helical CT. Each tumor underwent at least two CT scans. Tumor volume was determined using an area measuring tool and the summation-of-areas technique. Growth rate was evaluated in terms of diameter and volume changes. VDT and volume growth rate were compared in relation to several factors (initial diameter, initial volume, diameter growth rate, volume growth rate, tumor grade, tumor subtype, sex or age). Mean VDT of RCCs was 505 days. Mean diameter and volume growth rate were 0.59 cm/year and 19.1 cm 3 /year, respectively. For volume and diameter growth rate, tumors ≤4 cm showed lower rates than those >4 cm (P 0.05). Volume growth rate was moderately to strongly positively correlated with initial diameter, initial volume and diameter growth rate (P < 0.05). In conclusion, small RCCs grew at a slow rate both diametrically and volumetrically. More accurate assessment of tumor growth rate and VDT may be helpful to understand the natural history of RCC. (orig.)

  17. Meremehestiilis suvituskorter / Jana Rand

    Index Scriptorium Estoniae

    Rand, Jana, 1963-

    2005-01-01

    Sisearhitektide Irina Sisaski ja Artur Jõe (Sisask Design Studio) kujundatud perekond Bernovski ühetoaline suvituskorter (40 mø) korterelamus Pärnus. Korteri välisseinad on peaaegu tervenesti klaasist. Mööblikomplektid on valmistatud Eestis eritellimuse järgi. Kahetasapinnalist lage kaunistab 17. sajandist pärit merekaart. 9 värv. ill

  18. Wow! Tallinn! / Jaak Rand

    Index Scriptorium Estoniae

    Rand, Jaak

    2006-01-01

    Jüri Sillarti mängufilm "Kuldrannake". Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions. Lisatud Jüri Sillarti filmograafia lk. 83

  19. HTGR accident initiation and progression analysis status report. Volume VIII. Responses to comments on AIPA status report

    Energy Technology Data Exchange (ETDEWEB)

    Raabe, P.H.

    1977-01-01

    The first seven volumes of the report series provide formal documentation of the status of the ERDA-sponsored Accident Initiation and Progression Analysis (AIPA) study as of the end of FY75. That portion of the report was given broad distribution to government agencies, industrial organizations, and academic institutions. Comments on the Status Report have been actively solicited from these and other organizations. The volume presented (the eighth in the AIPA Status Report) documents all of the formal written comments that have been received as of September 30, 1976, together with the responses to those comments. The comments as presented are direct quotations from the manuscripts as submitted by the reviewers; none have been paraphrased. The comments are presented in the same order as submitted by the reviewers and are generally addressed individually.

  20. HTGR accident initiation and progression analysis status report. Volume VIII. Responses to comments on AIPA status report

    International Nuclear Information System (INIS)

    Raabe, P.H.

    1977-01-01

    The first seven volumes of the report series provide formal documentation of the status of the ERDA-sponsored Accident Initiation and Progression Analysis (AIPA) study as of the end of FY75. That portion of the report was given broad distribution to government agencies, industrial organizations, and academic institutions. Comments on the Status Report have been actively solicited from these and other organizations. The volume presented (the eighth in the AIPA Status Report) documents all of the formal written comments that have been received as of September 30, 1976, together with the responses to those comments. The comments as presented are direct quotations from the manuscripts as submitted by the reviewers; none have been paraphrased. The comments are presented in the same order as submitted by the reviewers and are generally addressed individually