Science.gov (United States)

PMID:20156044

UK PubMed Central (United Kingdom)

PurposeThe objective of this study is to evaluate the continence rate following reconstruction of the posterior urethral plate in robot-assisted laparoscopic radical prostatectomy...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

ABSTRACT Introduction. Postprostatectomy erectile dysfunction (ED) remains a serious quality-of-life issue. Recent advances in the understanding of the mechanism of postprostatectomy ED have stimulated great attention toward penile rehabilitation. Aim. This review presents and analyzes a contemporary series of the recent medical literature pertaining to penile rehabilitation therapy after radical prostatectomy (RP). Main Outcome Measures. The laboratory and clinical studies related to penile rehabilitation are analyzed. The validity of the methodology and the conclusion of the findings from each study are determined. Methods. The published and presented reports dealing with penile rehabilitation following RP in human and cavernous nerve injury in animal models are reviewed. Results. Exciti...

UK PubMed Central (United Kingdom)

OBJECTIVE: To test the hypothesis that perioperative transfusion of allogeneic and autologous red blood cells (RBCs) stored for a prolonged period speeds biochemical recurrence of prostate cancer...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

The optimal management of men with very favorable clinicopathological factors who develop biochemical recurrence (BCR) after radical prostatectomy (RP) has not been previously reported. Both local and systemic recurrences are unlikely in this cohort. This study examines their management and outcomes. Between October 2000 to March 2010, 1627 men underwent open RP by a single surgeon. In all, 448 (27.5%) met the following criteria for extremely low risk disease: preoperative PSA level <10?ng?ml?1, clinical stage T1c/T2a, Gleason score ?6, estimated cancer volume in the surgical specimen ?5% and no evidence for positive surgical margin. Undetectable PSA was defined as ?0.04?ng?ml?1. BCR was defined as PSA ?0.2?ng?ml&#...

Science.gov (United States)

Penile rehabilitation has been an area of intense study and debate over the last decade. Interest in this topic was stimulated by the observation that erectile dysfunction remained a significant problem after radical prostatectomy despite meticulous nerve-sparing technique. Smooth muscle alterations and fibrotic changes in the penis were identified as the underlying causes of penile atrophy, veno-occlusive dysfunction, and Peyronie's-like changes that were observed after surgery. Initial observations that intracavernous injection therapies used on a regular basis postoperatively resulted in improvements in the return of spontaneous erectile function led to the development of penile rehabilitation protocols. Chronic dosing of oral type V phosphodiesterase inhibitors is now commonly used by urologists after radical prostatectomy despite a lack of convincing evidence from randomized, placebo-controlled ...

UK PubMed Central (United Kingdom)

This paper deals with the indications for prostatectomy; the differential diagnosis of the symptomatology of bladder neck obstruction; and the factors influencing the choice of operation....Full Text Available

International Nuclear Information System (INIS)

Purpose: The results of therapy in 288 men with pathologic Stage C prostate cancer who underwent radical retropubic prostatectomy (RRP) were analyzed to determine the effects of adjuvant therapy. Methods and Materials: Twenty-seven of the 288 patients received preoperative neoadjuvant hormonal therapy (leuprolide acetate). Postoperatively, 60 patients received adjuvant radiotherapy (RT) to the prostate bed. Follow-up ranged from 3 to 83 months (median = 32 months). Freedom from failure (FFF) was defined as maintaining a serum PSA level of #<=# 0.3 ng/ml. Results: The FFF was 61% at 3 years and 45% at 5 years for the entire group. The FFF following RRP plus RT was 75% at 3 years and 57% at 5 years as compared to 56% at 3 years and 40% at 5 years for RRP without RT (p = 0.049). The FFF following RRP plus neoadjuvant hormonal therapy was 58% at 3 years and 40% at 5 years as compared to 60% at 3 years and 45% at 5 years following RRP without ...

Energy Technology Data Exchange (ETDEWEB)

One-electron oxidation of several derivatives of pyrazolin-5-one, including the drug antipyrine, were studied by pulse radiolysis of aqueous solutions. All the compounds were found to be oxidized by Br2 rapidly but considerably more slowly by weaker oxidants, such as peroxyl radicals. From redox equilibria using p-methoxyphenol and N,N,N',N'-tetramethyl-p-phenylenediamine as reference compounds, the one-electron oxidation potentials of the methyl-substituted 2-pyrazolin-5-ones were found to be in the range of 0.32-0.39 V versus normal hydrogen electrode. The relevance of these findings to the properties of the drug nafazatrom is discussed. Antipyrine was found to have a much higher oxidation potential, estimated as 1.2-1.5 V, which is rationalized on the basis of the phenyl substitution and lack of resonance stabilization of the radical cation.

DEFF Research Database (Denmark)

It is well established from experiments in premixed, laminar flames, jet-stirred reactors, flow reactors, and batch reactors that SO2 acts to catalyze hydrogen atom removal at stoichiometric and reducing conditions. However, the commonly accepted mechanism for radical removal, SO2 + H(+M) reversible arrow HOSO(+M), HOSO + H/OH reversible arrow SO2 + H-2/H2O, has been challenged by recent theoretical and experimental results. Based on ab initio calculations for key reactions, we update the kinetic model for this chemistry and re-examine the mechanism of fuel/SO2 interactions. We find that the interaction of SO, with the radical pool is more complex than previously assumed, involving HOSO and SO, as well as, at high temperatures also HSO, SH, and S. The revised mechanism with a high rate constant for H + SO2 recombination and with SO + H2O, rather than SO2 + H-2, as major products of the HOSO + H reaction is in agreement with ...

UK PubMed Central (United Kingdom)

The relation between the timing of prophylactic antibiotic administration and the occurrence of bacteraemia during transurethral operations was studied in 112 patients whose urine was infected before...Full Text Available

International Nuclear Information System (INIS)

The nature of radicals in wood irradiated in vacuum was studied by ESR method. The decay rate of radicals changes in three temperature ranges. Long-lived radicals are very stable at 298"0K, at which the wood-plastics composite has often been studied. The number of radicals formed by irradiations shows fairly good agreement with the total number of radicals in each isolated wood component. The graft copolymerization of MMA to irradiated wood was also studied by means of ESR, and it was found that PMMA propagating radicals are formed in irradiated wood. These radicals are probably formed by the result of graft copolymerization of MMA of wood. (auth.).

Energy Technology Data Exchange (ETDEWEB)

The rise of spam in the last decade has been staggering, with the rate of spam exceeding that of legitimate email. While conjectures exist on how spammers gain access to email addresses to spam, most work in the area of spam containment has either focused on better spam filtering methodologies or on understanding the botnets commonly used to send spam. In this paper, we aim to understand the origins of spam. We post dedicated email addresses to record how and where spammers go to obtain email addresses. We find that posting an email address on public Web pages yields immediate and high-volume spam. Surprisingly, even simple email obfuscation approaches are still sufficient today to prevent spammers from harvesting emails. We also find that attempts to find open relays continue to be popular among spammers. The insights we gain on the use of Web crawlers used to harvest email addresses and the commonalities of techniques ...

British Library Electronic Table of Contents (United Kingdom)

A 46-year-old man was referred to us after he presented to his local physician complaining of difficulty eating. Upper gastrointestinal endoscopy revealed a tumor at the esophagogastric junction (EGJ), and moderately differentiated adenocarcinoma was diagnosed from the biopsy findings. Computed tomography (CT) showed apparent enlargement of the pretracheal lymph nodes, the lymph nodes around the bilateral recurrent laryngeal nerves, and the lower thoracic paraesophageal lymph nodes, confirming metastasis. Since the disease was far advanced esophagogastric cancer with marked lymph node metastases throughout the mediastinum, curative resection would have been unlikely. Thus, he was commenced on systemic chemotherapy with cisplatin (90 mg/body, day 8) + S-1 (120 mg/body/day, given for 3 weeks...

UK PubMed Central (United Kingdom)

A vast amount of circumstantial evidence implicates oxygen-derived free radicals (especially, superoxide and hydroxyl radical) and high-energy oxidants [such as peroxynitrite (OONO⁻)]...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The authors present some recent measurements on electroweak physics using data collected by the CDF experiment at the Tevatron proton anti-proton collider ({radical}s = 1.96 TeV) at Fermilab.

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared

Energy Technology Data Exchange (ETDEWEB)

A method for the quantitative determination of atmospheric hydroperoxyl radical comprising: (a) contacting a liquid phase atmospheric sample with a chemiluminescent compound which luminesces on contact with hydroperoxyl radical; (b) determining luminescence intensity from the liquid phase atmospheric sample; and (c) comparing said luminescence intensity from the liquid phase atmospheric sample to a standard luminescence intensity for hydroperoxyl radical. An apparatus for automating the method is also included.

International Nuclear Information System (INIS)

Short note.

KoreaScience (Korea)

Full Text Available

International Nuclear Information System (INIS)

Experimental investigation data are systematized of free radical states and processes in irradiated proteins. The investigation is performed by the radiospectral methods. Results are discussed in detail of the study of free radicals electronic structure of amino acids, peptides and proteins formed by the action of ionizing radiation. The specificity is stressed of the study of monocrystalls of these compounds by the method of electronic paramagnetic resonance. The nature is also studied of primary centres formed under the effect of radiation on biologically important compounds and their subsequent reactions in solid and liquid solutions. Ion-radical states of different functional groups of the protein molecule are studied. Prospects of the study and the role of anion-radicals in biological processes are discusses.

Energy Technology Data Exchange (ETDEWEB)

Graft copolymerization of sodium styrene sulfonate (SSS) onto electron beam (EB) irradiated poly(vinylidene fluoride) (PVDF) films was investigated to find out a simple preparation process for sulfonic acid proton exchange membranes with respect to monomer concentration, absorbed dose, temperature, film thickness and storage time. The reaction order of the monomer concentration and absorbed dose of grafting was found to be 2.84 and 1.20, respectively. The overall activation energy for graft copolymerization reaction was calculated to be 11.36 kJ/mol. The initial rate of grafting was found to decrease with an increase in the film thickness. The trapped radicals in the irradiated PVDF films remained effective in initiating the reaction without considerable loss in grafting level up to 180 days, when stored under -60 {sup o}C. The presence and distribution of polystyrene sulfonate grafts in the obtained membranes were observed by Fourier transform ...

Energy Technology Data Exchange (ETDEWEB)

The role of intermediate products of dioxygen reduction in cytotoxic effects ascribed to oxygen molecules was studied in vivo using various yeast mutants with changed response to oxygen stress. It has been documented that superoxide radical exerts its deleterious effects on yeast cells directly and the role of other oxygen species derived from it is hardly detectable. Yeast Saccharomyces cerevisiae, however, cannot be considered as a typical eukaryotic organism due to its inability of synthesizing polyunsaturated fatty acids (pufa). These fatty acids are known as main target molecules during oxidative stress and their peroxidation leads to cytotoxic effects. As fatty acid content could be easily manipulated in yeast, this organism was used to evaluate the contribution of pufa peroxidation process to the cytotoxic effects of oxygen. Results obtained show, that yeast cells containing linolenic acid as the main constituent of phospholipids are hypersensitive to oxygen ...

International Nuclear Information System (INIS)

The radical cations from aziridine and azetidine have been characterized by ESR spectroscopy following their generation in the solid state by #gamma# irradiation of dilute solutions of the parent compounds in the CFCl_3 matrix at 77 K. The ESR parameters of the azetidine radical cation are typical of those for nitrogen-centered amine radical cations such as Me_2NH*"+. On the other hand, the radical cation formed from aziridine has very different ESR parameters that compare closely to those for the isoelectronic C...C ring-opened form of the oxirane radical cation and the allyl radical. The radical cation formed from azetidine is therefore assigned a ring-closed structure with the unpaired electron in a 2p/sub z/ orbital on nitrogen perpendicular to the ring plane, whereas the cation from aziridine is an allylic C...C ring-opened planar ...

UK PubMed Central (United Kingdom)

Objective. Cervical cancer patients who had an abandoned radical hysterectomy were evaluated for preoperative clinical predictors, complication rates, and outcomes. Study...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The OH-initiated photo-oxidation of n-butane was used as a source of 1- and 2-butoxy radicals. Reactions producing ketones and other organic compounds are explained. Rates of photolysis were determined and are discussed.

UK PubMed Central (United Kingdom)

BackgroundTrichloroethylene (TCE) may induce oxidative stress which generates free radicals and alters antioxidants or oxygen-free radical scavenging enzymes.MethodsTwenty...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

We have undertaken a program which measures the photoelectron spectra of negative-ion beams. This experiment has afforded us direct information about these ions and the corresponding neutral radicals. Several ions and numerous radicals are believed to be crucial intermediates in combustion processes and flame chemistry. We have fabricated a spectrometer which directly measures electron affinities (EA). Knowledge of the EA and gas-phase acidity of a radical has enabled us to deduce several radical heats of formation and bond strengths.

Wastenet

... Three prototype reactors were constructed and the photocatalysts used were TiO2 for hydroxyl radical generation, dyes such as methylene blue and rose bengal for singlet oxygen generation, and ferric chloride/hydrogen peroxide in Photo-Fenton OH radical generation. Singlet oxygen was effective against some of the pesticides but reacted slowly or not at all with others. All pesticides were degraded by OH radical generating agents (such as methylene blue)...

British Library Electronic Table of Contents (United Kingdom)

The extracts from kinnow peel, kinnow seeds, litchi pericarp, litchi seeds, grape seeds, and banana peel were screened for total phenolic content (TPC), trolox equivalent antioxidant capacity (TEAC), 1,1 diphenyl-2-picryl hydrazyl (DPPH) radical scavenging activity, as well as reducing power. Kinnow peel extract exhibited the highest reducing power, TEAC, and DPPH free radical scavenging activity, whereas, the phenolic content of 37.4 mg GAE/g-dw was highest for grape seed extract. Banana peel extract with a low TPC showed the lowest reducing power, TEAC as well as DPPH free radical scavenging activity among the fruit residue extracts examined in the present study. Correlation analysis between the reducing power and DPPH radical scavenging ability; reducing power and ABTS radical scavengin...

International Nuclear Information System (INIS)

Radical cations of various 3-methylalkanes (C_6-C_1_4) have been produced and stabilized by #gamma#-irradiation of the corresponding neutral compounds in saturated chlorofluorocarbon and perfluorocarbon matrices at 77 K. The perfluorocarbon matrices appeared more suitable for studies of the lighter radical cations, whereas the chlorofluorocarbon matrices were more suited for studies of the heavier radical cations; intermediary cations could be studied in both types of matrices. After irradiation, electronic absorptions associated with both the matrix and the alkane additive were observed. Pure spectra of the 3-methylalkane radical cations were obtained by difference spectrometry, after selective elimination of these cations by illumination. The electronic absorption spectra of the 3-methylalkane radical cations consist in all cases of a single broad absorption band. The spectral ...

International Nuclear Information System (INIS)

The mono- and intramolecular cation-radicals (CR) reactions of diethylmercury in the CFCl_3, CFCl_2CF_2Cl matrices and CF_2BrCF_2Br and CFCl_3 freons vitrified mixture (1:1) were studied through the EPR method. Formation of radical products of transformations of the initial CR diethylmercury (X-ray radiation dose - 100-200 Gy at the temperature of 293 K) was studied through the spin trap of 2.4.6 - tri-tret-butylnitrosebenzene.

British Library Electronic Table of Contents (United Kingdom)

PurposeTo conduct a retrospective analysis within a large university teaching hospital, comparing outcomes between patients receiving either radical surgery or radiotherapy as curative treatment for bladder cancer.Patients and MethodsBetween March 1996 and December 2000, 169 patients were treated radically for muscle-invasive bladder cancer. Data were collected from patient notes. Statistical analyses were performed using Kaplan-Meier methods and Cox proportional hazards regression analysis to compare radiotherapy and surgical outcome data.ResultsThere was no difference in overall, cause-specific, and distant recurrence-free survival at 5 years between the two groups, despite the radiotherapy group being older (median age, 75.3 years vs. 68.2 years). There were 31 local bladder recurrences...

International Nuclear Information System (INIS)

Pulsed radiolysis method is used to study transformations intermediates of 6-aminophenalenone in ethanol. In alkaline medium the main product is radical-anion of 6-aminophenalenone, which optical absorption spectrum contains two bands with maxima at 355 and 400 nm. The particle precursors are e_s, CH_3CHOH and CH_3CHO"- radicals. In neutral and acid medium radical-anions are protonated in reactions with alcohol and hydrogen ions. The resulting H-adduct of 6-aminophenalenone has optical absorption maxima at 350 and 390 nm. Availability of two maxima is related to two various product structures. Molar extinction coefficients of radical-anions and H-adducts of 6-aminophenalenone and rate constants of reactions with their participation are estimated.

British Library Electronic Table of Contents (United Kingdom)

The n3 and n4 vibrational transitions of CH3 and CD3 isolated in solid parahydrogen were studied by high-resolution infrared spectroscopy. The radicals were produced by in situ UV photolysis of methyl iodides trapped in solid parahydrogen. The observed spectra showed clear rotational fine structures, which were subjected to further splitting due to the electrostatic field of solid parahydrogen. The molecular constants and crystal field parameters of the radicals in solid parahydrogen were determined by analyzing the spectral structures of the n3 and n4 transitions of CD3 by the crystal field theory. The rotational constants of the CD3 radical were found to be only a few percent smaller than those in the gas phase. The determined crystal field parameters indicated significant quantum effect...

International Nuclear Information System (INIS)

There are several methods of generating OH free radicals from ozone and/or hydrogen peroxide and ultraviolet light. They all have in common that the OH free radicals originate in one single source only whereas in the combination of ozone with ionizing radiation two simultaneous working sources for the OH free radicals exist. The resulting higher OH free radical concentration makes this process especially apt for the remediation of low level contaminated groundwater as for example trichloroethylene (TCE) contamination in the sub-ppm range. A cost comparison between O_3/UV and O_3/electron beam for remediation of a groundwater contaminated with 100 ppb TCE indicated that for a throughput of about 5 million gallons/day the O_3/electron beam process is more cost-effective. (authors).

International Nuclear Information System (INIS)

Ultra low loading noble metal (0.04-0.12 mg_P_t/cm"2) based electrodes were obtained by direct metallization of non-catalyzed gas diffusion layers via dual ion beam assisted deposition (IBAD) method. Fuel cell performance results reported earlier indicate significant improvements in terms of mass specific power density of 0.297 g_P_t/kW with 250 A thick IBAD deposit (0.04 mg_P_t/cm"2 for a total MEA loading of 0.08 mg_P_t/cm"2) at 0.65 V in contrast to the state of the art power density of 1.18 g_P_t/kW using 1 mg_P_t_(_M_E_A_)/cm"2 at 0.65 V. In this article we report the peroxide radical initiated attack of the membrane electrode assembly utilizing IBAD electrodes in comparison to commercially available E-TEK (now BASF Fuel Cell GmbH) electrodes and find the pathway of membrane degradation as well. A novel segmented fuel cell is used for this purpose to relate membrane degradation to peroxide generation at the electrode/electrolyte interface ...

Energy Technology Data Exchange (ETDEWEB)

Decomposition yields of tetracycline sulphate and oxytetracycline sulphate were determined in argon saturated 0.1N H/sub 2/SO/sub 4/ solutions. The decomposition yields of teracyclines decrease in the presence of the Cl/sup -/ ions. The reaction rate constants of the OH radicals with tetracyclines were also determined.

International Nuclear Information System (INIS)

Practical procedures were developed for large-scale microbial decontamination of dry egg powder and gelatine with gamma radiation ("6"0Co). The formation and lifes of free organic radicals in these materials were examined by ESR measurements of powder samples. The concentration of these radicals was studied in dependence on the time of storage. Secondary oxidation of egg fats by air oxygen was investigated. Sensoric tests of irradiated gelatine, both in powder and hydrogel form, were performed. (author). 4 figs., 2 tabs., 2 refs.

International Nuclear Information System (INIS)

The high-energy radiation-induced degradation of an H-acid derivative azo dye, Apollofix-Red SF-28 (AR-28) was studied in aqueous solution by using pulse radiolysis with kinetic spectroscopic detection for transient measurements. Gamma radiolysis with UV-VIS spectroscopy and gradient ionpair HPLC separation with diode array detection were applied for following the destruction of AR-28 and measuring the products. The reactions of hydrated electron (e_a_q "-) and hydroxyl ("#centre dot#OH) radical were investigated separately. "#centre dot#OH reacts with the unsaturated bonds of the molecule. In the further reactions of the "#centre dot#OH adduct radicals, the AR-28 molecules partly reform with a slightly modified structure. The products formed in the first reaction of "#centre dot#OH and AR-28 molecules have also high reactivity towards the "#centre dot#OH radicals. For these reasons the efficiency of "#centre dot#OH ...

CERN Document Server

Yost finds yet another reason to be paranoid

Energy Technology Data Exchange (ETDEWEB)

Hyperquenching of liquid water with cooling rates of 10{sup 6}-10{sup 7} K s{sup -1} yields glassy water. Upon {gamma}-irradiation at 77 K, the only paramagnetic species accumulating in hyperquenched glassy water are the hydroxyl and hydroperoxyl radicals. There are no hydrogen atoms or electrons seen by the ESR technique. For irradiation doses up to about 70 kGy, the relative contributions of hydroxyl and hydroperoxyl radicals to the total amount of paramagnetic species remain virtually constant. The total amount of paramagnetic species, n, is sublinear in dose, d, well approximated by n=8.55x10{sup 16}d{sup 0.8} for n in spin g{sup -1} and d in kGy.

Science.gov (United States)

Pulse radiolysis studies of the formation kinetics and the yields of various phenylcarbenium ions from several different solutes in 1,2-dichloroethane solution have been carried out. The results indicate that there are two kinetically distinguishable cationic species of the solvent which react selectively with the different solutes to form the phenylcarbenium ions. It is suggested that one is a cation radical (yield 0.68 molecule/100 eV) and the other a carbocation (yield 0.20 molecule/100 eV). Rate constants for their separate reactions with selected aromatic compounds and with ammonia have been determined. Molar extinction coefficients have been estimated for benzyl cation, diphenyl cation radical, and anthracene cation radical. 6 figures, 1 table.

International Nuclear Information System (INIS)

Using hydrogen at high pressures of up to 150 bar as an OH scavenger in aqueous MV"2"+ solutions (pH 1) it is possible to differentiate between two kinds of transient formed simultaneously by H-atom attack on methyl viologen. One of them is assigned to an H adduct on the N atom, MV"+H"+, with absorption bands identical to those of the radical cation, MV"+. The MV"+H"+ species deprotonates forming the long-lived radical cation, MV"+. The second type of transient produced is attributed to an H-adduct on the ring carbon, MV"2"+H, decaying by second-order kinetics. The formation of MV"+ by electron transfer from the propan-2-ol radical has been reinvestigated (pH 0 to 7); its absorption spectrum does not change in this pH range. Rate constants and molar extinction coefficients are presented. (U.K.).

UK PubMed Central (United Kingdom)

Exercise training is known to induce an increase in free radical production potentially leading to enhanced muscle injury. Vitamins C and E are well known antioxidants that may prevent muscle cell damage....Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The authors report on a search for pair production of first-generation scalar leptoquarks (LQ) in p{bar p} collisions at {radical}s = 1.96 TeV using an integrated luminosity of 252 pb{sup -1} collected at the Fermilab Tevatron collider by the D0 detector. They observe no evidence for LQ production in the topologies arising from LQ{ovr LQ} {yields} eqeq and LQ{ovr LQ} {yields} eqvq, and derive 95% C.L. lower limits on the LQ mass as a function of {beta}, where {beta} is the branching fraction for LQ {yields} eq. The limits are 241 and 218 GeV/c{sup 2} for {beta} = 1 and 0.5, respectively. These results are combined with those obtained by D0 at {radical}s = 1.8 TeV, which increases these LQ mass limits to 256 and 234 GeV/c{sup 2}.

UK PubMed Central (United Kingdom)

BackgroundThe optimal treatment for locally recurrent rectal cancer (LRRC) is still a matter of debate. This study assessed the outcome of LRRC patients treated with multimodality...Full Text Available

UK PubMed Central (United Kingdom)

Recurrent tumour after radical pancreaticoduodenectomy may cause obstruction of the small bowel loop draining the liver. Roux-loop obstruction presents a particular therapeutic challenge, since the...Full Text Available

UK PubMed Central (United Kingdom)

Because copper catalyzes the conversion of H₂O₂ to hydroxyl radicals in vitro, it has been proposed that oxidative DNA damage may be an important component of copper toxicity....Full Text Available

Energy Technology Data Exchange (ETDEWEB)

It was previously reported that the tritium tracer method is useful for the quantitative consideration of hydrogen behavior in coal during coal liquefaction reaction. Tetralin is excellent hydrogen donating solvent, and is considered as one of the model compounds of coal. In this study, effects of H2S and H2O on the hydrogen exchange reaction between tetralin and gaseous hydrogen labeled by tritium were investigated. It was suggested that the conversion of tetralin and the hydrogen exchange reaction between gaseous hydrogen and tetralin proceed through the radical reaction mechanism with a tetralyl radical as an intermediate product. When H2S existed in this reaction, the hydrogen exchange yield increased drastically without changing the conversion yield. This suggested that the hydrogen exchange reaction proceeds even in the reaction where radical does not give any effect. In the case of H2O addition, the conversion yield ...

Energy Technology Data Exchange (ETDEWEB)

The dissociation of methylal is investigated using mass spectrometry, combined with a pyrolytic radical source and femtosecond pump probe experiments. Based on preliminary results two reaction paths of methylal dissociation are proposed and discussed. (author) 4 fig., 3 refs.

Energy Technology Data Exchange (ETDEWEB)

The development of detailed chemical kinetic reaction mechanisms for oxidation of n-octane and iso-octane is described, with emphasis on the factors which are specific to many large hydrocarbon fuel molecules. Elements which are of particular importance are found to include site-specific abstraction of H atoms, radical isomerization of alkyl radicals by internal H atom abstraction, and rapid ..beta..-scission of the alkyl radicals. These features, combined with distinctions in the types of intermediate olefin species produced, are used to explain the significant differences in the rate of oxidation between n-octane and iso-octane. Experimental results from the turbulent flow reactor and low pressure laminar flames, using both n-octane and iso-octane as fuels, are used to test the reaction mechanisms and indicate those parts of the total mechanisms which are in greatest need of further development and refinement. It is found ...

UK PubMed Central (United Kingdom)

The free radical theory of ageing posits that accrual of oxidative damage underlies the increased cellular, tissue and organ dysfunction and failure associated with advanced age. In support of this...Full Text Available

International Nuclear Information System (INIS)

Pulse radiolysis has been used to optically and kinetically characterize the transient free radicals formed by the reaction of H"s"m"-"b"u"l"l"e"t, N_3"s"m"-"b"u"l"l"e"t, or OH"s"m"-"b"u"l"l"e"t with 2,4,5-trichlorophenol (TCP-OH). The hydroxy-2,4,5-trichlorocyclohexadienyl radical (H-TCP-OH) formed by H"s"m"-"b"u"l"l"e"t addition to TCP-OH [k = (1.1 #+-# 0.2) x 10"9 M"-"1 s"-"1] has an absorption maximum at 360 nm with #epsilon#_3_6_0 = (4700 #+-# 1000) M"-"1 cm"-"1. The 2,4,5-trichlorophenoxyl radical (TCP-O"s"m"-"b"u"l"l"e"t) formed by the reaction of N_3"s"m"-"b"u"l"l"e"t with TCP-O- [k = (4.3 #+-# 0.8) x 10"9 M"-"1 s"-"1] has an absorption maximum at 430 nm with #epsilon#_4_3_0 = (3600 #+-# 600) M"-"1 cm"-"1. The dihydroxy-2,4,5-trichlorocyclohexadienyl radical (HO-TCP-OH) formed by OH"s"m"-"b"u"l"l"e"t radical addition to TCP-OH [k = (1.2 #+-# 0.1) x 10"1"0 M"-"1 s"-"1] has an ...

Energy Technology Data Exchange (ETDEWEB)

Forty-three patients with basal and squamous cell carcinomata arising on the pinna were treated radically using a 10 MeV electron beam. The technique and dosage are described and discussed. Primary cancer control with retention of the pinna was achieved in 34 patients. Salvage pinnectomy was performed in four patients for recurrence and one patient for radiation necrosis. Two patients with large primary tumours failed to resolve and died of their disease. The advantages for the patient of the policy of primary radical electron beam therapy are discussed.

Energy Technology Data Exchange (ETDEWEB)

The authors present a measurement of the B{sub s}{sup 0} meson lifetime using fully and partially reconstructed hadronic decays B{sub s}{sup 0} {yields} D{sub s}{sup -} {pi}{sup +}(X) followed by D{sub s}{sup -} {yields} {phi}{pi}{sup -}. The data sample was recorded with the CDF II detector at the Fermilab Tevatron and corresponds to an integrated luminosity of 1.3 fb{sup -1} from p{bar p} collisions at {radical}s = 1.96 TeV.

KoreaScience (Korea)

Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Detailed chemical kinetic reaction mechanisms are developed for combustion of all nine isomers of heptane (C{sub 7}H{sub 16}), and these mechanisms are tested by simulating autoignition of each isomer under rapid compression machine conditions. The reaction mechanisms focus on the manner in which the molecular structure of each isomer determines the rates and product distributions of possible classes of reactions. The reaction pathways emphasize the importance of alkylperoxy radical isomerizations and addition reactions of molecular oxygen to alkyl and hydroperoxyalkyl radicals. A new reaction group has been added to past models, in which hydroperoxyalkyl radicals that originated with abstraction of an H atom from a tertiary site in the parent heptane molecule are assigned new reaction sequences involving additional internal H atom abstractions not previously allowed. This process accelerates autoignition in fuels with ...

International Nuclear Information System (INIS)

The purpose was to study the toxicity of drugs known to generate free radicals on isolated pancreatic islets. The accumulattion of "8"6Rb"+ by mouse pancreatic islets was measured in vitro. Exposing the islets to 6-hydroxydopamine, minhydrin, or phenazine methosulphate + NADH inhibited the Rb"+ uptake, whereas paraquat or acetylphenylhydrazine had no effect. This effect of 6-hydroxydopamine was prevented by either of the hydroxyl radical scavengers, sodium benzoate and mannitol, but not by the non-scavenger,urea; ninhydrin was partially protected against by mannitol but not by benzoate. Protection against 6-hydroxydopamine was also afforded by D-glucose but not by L-glucose or 3-O-methyl-D-glucose; none of the sugars protected against ninhydrin. In damaging islet beta-cells and in being protected against by D-glucose, 6-hydroxydopamine closely resembles the diabetogenic drug, alloxan. It is suggested that protection against alloxan may involve ...

International Nuclear Information System (INIS)

Lysozyme dimers produced on oxidation of lysozyme with Br_2anion radicals in aqueous solutions exhibit a fluorescence spectrum (lambdasub(max) = 400 nm) closely similar to that of bi-tyrosine. This suggests that the dimer is likely to have a tyrosine-tyrosine bond resulting from the combination of tyrosine phenoxy radicals of two lysozyme molecules. Kinetic studies on dimer formation were made by measuring time-dependent fluorescence after pulsed-electron irradiation over wide pH range. The results lead to the following conclusions. The second-order growth of the dimer fluorescence observed at pH 10.7-12.5 reflects the combination process of the lysozyme radicals, which is rate-determining in the pH range. On the other hand, the first-order growth observed at pH 6.8-10.2 is attributable to the enolization of the keto-form of the dimer. A tentative reaction scheme is proposed for the dimer formation. (author).

International Nuclear Information System (INIS)

To elucidate the mechanism of sunlight-induced skin damage, guinea pigs exposed to UV light (280-320 nm, UV B, 4J/cm"2) and a homogenate of the epidermis was examined by means of the thiobarbituric acid (TBA) test. Three hours after the exposure, TBA-malondialdehyde adducts had increased while glutathione reductase activity had decreased, indicating lipid peroxidation. To detect the initial species, spin trapping with 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) was applied to a suspension of illuminated epidermal cells (0.5 J/cm"2). An ESR signal obtained only with irradiation comprised a 1 : 2 : 2 : 1 quartet [a (N) =a (#beta#H) =1.49 mT] attributable to a spin adduct of hydroxyl radicals. These results suggest that sunlight exposure of skin may lead to hydroxyl radical generation and simultaneous lipid peroxidation. (author).

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Two measurement methods to determine the rate of neutral free radical production by the photo-deionization of negative ion beams (PDINIB) are introduced. These methods, namely, photoelectron-current measurement by low-frequency electro-modulation probe (PMMP) and measurement of decrease in the negative-ion beam current (DNIC) were employed to evaluate the production rate in a trial surface-processing apparatus developed in the author's laboratory utilizing a steady-flux refined beam of neutral free radicals (RBNR) produced by the PDINIB procedure. A {sup 63}Cu{sup -} negative ion beam of kinetic energy E{sub i} varied up to 15 keV was irradiated with a 514.5 nm visible light beam from a 25 W CW Ar{sup +} ion laser. The detection limit of the production rate by the PMMP setup was as high as 6 x 10{sup 9} s{sup -1} under the condition that E{sub i}=15 keV, the negative-ion beam current I{sub i}=4 {mu}A and the laser power P=6 W. The DNIC ...

International Nuclear Information System (INIS)

Recent work has shown that natural hydrocarbon emissions can significantly affect the levels of urban and regional tropospheric ozone. We report on the reactivities of these biogenic trace gases, particularly isoprene, focusing on their importance in the production of aldehydes and peroxy radicals, leading to increased levels of hydrogen over regional forests. Hydrogen peroxide can lead to the wet oxidation of sulfur dioxide to acidic sulfate in aerosols, fogs, and clouds. In turn, acidic sulfate can act to as a light scattering aerosol and a source of cloud condensation nuclei (CCN), potentially leading to global cooling. Aerosol sulfate and other dissolved organic and inorganic compounds can also play important roles as a greenhouse species in the lower troposphere.

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The authors search Z{prime} bosons in dielectron events produced in p{bar p} collisions at {radical}s = 1.96 TeV, using a 0.45 fb{sup -1} dataset accumulated with the CDF II detector at the Fermilab Tevatron. To identify the Z{prime} {yields} e{sup +}e{sup -} signal, both the dielectron invariant mass distribution and the angular distribution of the electron pair are used. No evidence of a signal is found, and 95% confidence level lower limits are set on the Z{prime} mass for several models. Limits are also placed on the mass and gauge coupling of a generic Z{prime}, as well as on the contact interaction mass scales for different helicity structure scenarios.

International Nuclear Information System (INIS)

The radiation induced reactions in LDPE in the presence of phenolic type antioxidants have been studied. It was shown that various antioxidants can influence the polyethylene network formation and the radical yield in different ways. The dependence of network structure on absorbed doses was determined by gel analysis, hot-set test and extraction of antioxidants for samples irradiated with accelerated electrons. It was found that the antioxidants eluted from polyethylene in higher percentage influence polymer crosslinking to a smaller degree. The ESR studies of #gamma#-irradiated blends of polyethylene with antioxidant indicate the presence of alkyl and phenoxyl radicals. The role of antioxidant molecules on radiation induced reactions in polyethylene-antioxidant systems is considered. The correlation between the network structure and the type of additive in polyethylene is also discussed. (author).

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Five arylethylenes with 1-naphthyl, 2-naphthyl, and phenyl groups in 1,2-positions have been studied for singlet-mediated charge-transfer interactions with several amines and paraquat dication. 1-Phenyl-2-(2-naphthyl)ethylene and 1,2-di(2-naphthyl)ethylene exhibit distinct dependence of exciplex emission maxima and lifetimes, and fluorescence quenching constants, on excitation and/or monitoring wavelengths; this is in conformity with the existence of ground-state rotamers for these systems, wtih distinguishable absorption-emission spectra and fluorescence lifetimes. The fluorescence quenching by aromatic amines and paraquat dication occurs with rate constants in the limit of diffusion control and is accompanied by the formation of radical ions in polar solvents (acetonitrile). The transient spectra and kinetics associated with the radical ions, observed by 337.1- and 355-nm laser flash photolysis, are also reported. 10 figures, 4 tables.

British Library Electronic Table of Contents (United Kingdom)

Oxidative degradation of methylene blue (MB) by Co^2^+-HCO3^- system with H2O2 in aqueous solution was studied. Nearly complete decolorization of the dye was obtained in less than 50min in diluted NaHCO3 solution (25mM) in the presence of only 20mM Co^2^+ ions. Meanwhile, the conjugated structure and phenyl rings of the MB molecule were destroyed or even broken down into small organic acids and inorganic ions, as indicated by FT-IR spectra and ion-chromatography. Photoluminescence probing and radical scavenging technologies suggested that the reaction of MB degradation in this system mainly involved the generation and participation of hydroxyl radicals. Furthermore, by cyclovoltammetric measurements, the in situ formed different complexes between Co^2^+ and HCO3^- were observed at differen...

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The reactions of the hydroxyl radical with hydrocarbons and fluoro hydrocarbons attract significant attention due to their importance in atmospheric chemistry. Its reactions with the two first hydrocarbons, methane and ethane are of special interest because, owing to the small size of these systems, they serve as a prototype for the theoretical studies of hydrogen abstraction reactions. In this work, the reaction and activation energies of the hydroxyl radical abstraction reaction with methane and ethane have been investigated by correlated ab initio and DFT methods. The DFT reaction energies are in good agreement with experimental values, but the activation energies may be in severe error. (authors) 22 refs.

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Gastric stromal tumors are an ill-defined group of lesions arising from muscle wall cells and characterized by extremely variable biological patterns. Thanks to modern immunohistochemical and ultrastructural techniques, four main classes of these lesions have been identified, namely: (1) tumors with differentiation toward smooth muscle cells; (2) tumors with differentiation toward neural elements; (3) tumors with differentiation toward neural elements; (3) tumors with dual differentiation toward either cell type. It was investigated the yield of CT in diagnosing and characterizing gastric stromal tumors. It was retrospectively reviewed the CT findings of 38 patients (15 men and 23 women; mean age 51 years) with pathologically proven gastric stromal tumors, namely 31 of myoid origin, 4 of neural origin, 2 with both muscle and neural differentiation, 1 lacking differentiation with either cell type. The myoid tumors involved gastric fundus in 9/13 and 5/7 benign ...

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Although silicosis has been studied extensively, the mechanism is still not fully understood. Experiments do provide evidence that the actions of unique properties of silica surface on the cell membrane are the starting point of silicotic processes. This paper summarizes literature on chemical properties of silica surface, and the effect of particle size on silica toxicity. This paper also discusses the ways in which silica dusts are though to interact with the cell membrane, with emphasis on freshness, hydrogen bonding, and free-radical interactions.

International Nuclear Information System (INIS)

The purpose of work is systematical studying of benzo (B) of thiophene-1,1-dioxides and their 2,3-di-hydro derivatives behaviour in the reactions of electrophflic, radical, nucleophilic nitration, reduction of nitro group, embodiment of synthesis of N-amino derivatives, investigation of sulfur containing hetero-cyclic compounds, including of residues of some steroids

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We demonstrate the nonuniqueness of the basic assumptions leading to spiral structure in self-propagating star formation models. Even in the case where star formation occurs purely spontaneously and does not propagate, we have generated spiral structure by adopting the radically different assumption where star formation is systematically inhibited.

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There have been no radically new commercial bulk explosives since Atlas Powder Company's introduction of emulsions onto the market in 1968. But the effectiveness, safety and management of these familiar explosives is continuously being improved by the development of blast design techniques, explosives delivery and initiation systems, and monitoring methods. The author looks at developments in blasting technology and discusses experiences with Handibulk emulsion delivery systems.

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The introduction of CT scan and, more recently, magnetic resonance imaging, has radically changed the diagnostic approach to tumors developed in the internal auditory canal and cerebellopontine angle. CT scan with intravenous injection visualizes tumors lying in the cerebellopontine angle. Magnetic resonance imaging, especially using gadolinium, is a very accurate means for diagnosing tumors of both the auditory canal and cerebellopontine angle.

British Library Electronic Table of Contents (United Kingdom)

Abstract High Post-Modernism with its understanding of the significance of the image anticipated the flattening of culture, first in advertising and the printed media, and more recently online. Sam Jacob of FAT speculates on architecture's relationship with the Internet, -a flatland of undifferentiated information-, and how Radical Post-Modernism might be best placed to resist the ubiquity of global culture while reanimating the social and cultural agenda of Modernism and Post-Modernism. Copyright 2011 John Wiley & Sons, Ltd.

British Library Electronic Table of Contents (United Kingdom)

Abstract Rationale, aims and objectives- Finding ways to incorporate disparate types of evidence into research syntheses has the potential to build a better evidence base for clinical practice and policy. Yet conducting such mixed research synthesis studies is challenging. Researchers have to determine whether and how to use adjusted and unadjusted quantitative findings in combination with each other and with qualitative findings. Methods- Among quantitative findings, adjustment for confounding, either via study design or statistical analysis, can be a considerable source of heterogeneity. Yet there is no consensus about the best way to synthesize findings resulting from different methods for addressing confounding. When synthesizing qualitative and quantitative findings, additional consid...

Science.gov (United States)

W. E. B. Du Bois, one of the brightest lights in African American history, wrote a sparkling critique of the American social and economic system originally planned as part of the Bronze Booklets series, edited and published by Alain Locke and the Associates in Negro Folk Education. The piece was never published and has, until now, been lost to the annals of adult education history. Using historical evidence, the authors examine Du Bois's Basic American Negro Creed and the circumstances that led to its exclusion from the series. It is argued that the Creed was far too radical for the liberal minded Carnegie Corporation and its leaders who were only interested in accommodating adult education for Blacks through the AAAE funded Bronze Booklets. The exclusion of the Creed represents an example of repressive tolerance by the AAAE.

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A number of amines can be employed for all volatile treatment (AVT) of steam generator (SG) systems of nuclear power reactors. These amines form complexes with Cu{sup 2+} and Ni{sup 2+} ions which come into water due to corrosion. The redox reactions of a number of Cu(II)-AVT amine complexes and the stability of the transient species formed have been studied by pulse radiolysis technique. Rate constants for the reaction of e{sub aq}{sup -} with a number of Cu(II)-amine complexes have been determined by following the decay of e{sub aq}{sup -} absorption. Stability of Cu(I)-amine complexes was studied by following the kinetics of the bleaching signal formed at the {lambda}{sub max} of the Cu(II) amine complex. Except for Cu(I)-triethanolamine complex all other Cu(I)-amine complexes were found to be stable. One-electron oxidation of Cu(II) amine complexes was studied using azidyl radicals for the oxidation reaction as OH radicals react with the ...

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The authors measure the dipion mass spectrum in X(3872) {yields} J/{psi}{pi}{sup +}{pi}{sup -} decays using 360 pb{sup -1} of {bar p}p collisions at {radical}s = 1.96 TeV collected with the CDF II detector. The spectrum is fit with predictions for odd C-parity ({sup 3}S{sub 1}, {sup 1}P{sub 1}, and {sup 3}D{sub J}) charmonia decaying to J/{psi}{pi}{sup +}{pi}{sup -}, as well as event C-parity states in which the pions are from {rho}{sup 0} decay. The latter case also encompasses exotic interpretations, such as a D{sup 0}{bar D}*{sup 0} molecule. Only the {sup 3}S{sub 1} and J/{psi} {rho} hypotheses are compatible with the data. Since {sup 3}S{sub 1} is untenable on other grounds, decay via J/{psi} {rho} is favored, which implies C = +1 for the X(3872). Models for different J/{psi}-{rho} angular momenta L are considered. Flexibility in the models, especially the introduction of {rho}-{omega} interference, enable good descriptions of the data for both L = 0 and 1.

International Nuclear Information System (INIS)

The EUROTRAC sub-project ''Tropospheric Ozone Research'' (TOR) follows a dual strategy: - Observation of the chemical processes contributing to the oxygen balance directly in the atmosphere; - Establishment of a validated data base for model calculations. Both tasks require simultaneous measurements of a wide range of chemical and meteorological components. In the case of the investigation of the chemical processes, it is also desirable to measure the free radicals directly involved in ozone production. In the project described, a measuring station was set up. For a period of two years and a half, continuous measurements were made of ozone and its chemical precursors (NO, NO_2, NO_y, VOC, CO), as well as other photooxidants (H_2O_2 and organic hydroperoxides, organic nitrates), the photolysis frequency of NO_2, and meteorological parameters (wind, temperature, moisture, aerosols). The station was located on the Schauinsland mountain in the southern Black Forest, at ...

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The Green-Chasman lattice, which is the basis for both NSLS storage rings, was conceived with insertion devices in mind. Long, field-free straight sections were provided in the design. The electron optics were chosen so that these sections had zero dispersion and the effects of new magnetic structures placed in these regions would have minimal effect on the emittance of the electron beam. This design concept has been followed by all high-brightness rings which were built subsequent to the NSLS. The X-Ray Ring straight sections also have a very small vertical {beta} function, in addition to the zero dispersion. This was done to optimize the brightness of wiggler sources. There is a further benefit however. The {beta} function determines the beam size and divergence at a particular point in the storage ring lattice. The size is proportional to {radical}{beta} and the divergence is proportional to 1/{radical}{beta}. Thus the electron beam is very ...

International Nuclear Information System (INIS)

The addition of paraquat (methyl viologen) to a growing culture of Escherichia coli K-12 led within 1 hr to a 10- to 20-fold increase in the level of endonuclease IV, a DNase for apurinic/apyrimidinic sites. The induction was blocked by chloramphenicol. Increases of 3-fold or more were also seen with plumbagin, menadione, and phenazine methosulfate. H_2O_2 produced no more than a 2-fold increase in endonuclease IV activity. The following agents had no significant effect: streptonigrin, nitrofurantoin, tert-butyl hydroperoxide, #gamma# rays, 260-nm UV radiation, methyl methanesulfonate, mitomycin C, and ascorbate. Paraquat, plumbagin, menadione, and phenazine methosulfate are known to generate superoxide radical anions via redox cycling in vivo. A mutant lacking superoxide dismutase was unusually sensitive to induction by paraquat. In addition, endonuclease IV could be induced by merely growing the mutant in pure O_2. The levels of endonuclease IV in uninduced or ...

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We present a systematic analysis of backward pion photoproduction for the reactions {gamma}p{yields}{pi}{sup 0}p and {gamma}p{yields}{pi}{sup +}n. Regge phenomenology is applied at invariant collision energies above 3GeV in order to fix the reaction amplitude. A comparision with older data on {pi}{sup 0}- and {pi}{sup +}-photoproduction at {theta}=180 indicates that the high-energy limit as given by the Regge calculation could be reached possibly at energies of around {radical}(s){approx_equal}3 GeV. In the energy region of {radical}(s){<=}2.5 GeV, covered by the new measurements of {gamma}p{yields}{pi}{sup 0} p differential cross-sections at large angles at ELSA, JLab, and LEPS, we see no clear signal for a convergence towards the Regge results. The baryon trajectories obtained in our analysis are in good agreement with those given by the spectrum of excited baryons. (orig.)

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The reactions of native bovine catalase with superoxide and solvated electrons have been investigated using three different methods for generating these reducing substrates: [gamma]-radiolysis of oxygenated or deaerated buffer solutions in the presence of an OH radical scavenger; either xanthine or acetaldehyde with xanthine oxidase; and low-temperature (77 K) [gamma]-radiolysis of buffered ethylene glycol/water solutions with subsequent annealing of samples at 183 K. (Author).

International Nuclear Information System (INIS)

Purpose: We present an update analysis of the multiinstitutional Ewing's sarcoma study CESS 86. Methods and Materials: From January 1986 through June 1991, 177 patients with localized Ewing's sarcoma of bone, aged 25 years or less, were recruited. Chemotherapy consisted of four 9-week courses of vincristine, actinomycin D, cyclophosphamide, and adriamycin (VACA) in low-risk tumors (extremity tumors =# 100 cm"3). Local therapy was an individual decision in each patient and was either radical surgery (amputation, wide resection) or resection plus postoperative irradiation with 45 Gy or definitive radiotherapy with 60 Gy (45 Gy plus boost). Irradiated patients were randomized concerning the type of fractionation in either conventional fractionation (once daily 1.8-2.0 Gy, break of chemotherapy) or hyperfractionated split-course irradiation simultaneously with the VACA/VAIA chemotherapy (twice daily 1.6 Gy, break of 12 days after 22.4 Gy and 44.8 Gy, total dose and ...

International Nuclear Information System (INIS)

This short communication aims to update the review of non-nitro radiation sensitizers (Shenoy and Singh 1985) and correct omissions. Work is mentioned and bibliography given for studied of cis-platinum, potassium permanganate, cobalt hexammine, sodium bromide, dimethylsulphoxide, zinc and copper ions, organic nitroxyl free radicals (TAN,TMPN and NPPN + PNAP), halogenated pyrimidines, organic and inorganic iodine containing compounds, diacetyl, acetone and acetophenone, rho-hydrobenzoic acid and its esters, pentobarbitone and secobarbitone, heparin and 9-anilinoacridines, dehydropiandosterone and paraquat. (U.K.).

International Nuclear Information System (INIS)

Nano-materials in which a large fraction of atoms resides within a few atomic layers near the surface can be designed to have novel properties by manipulating their surface parameters. We show that the effective elastic constants of nano-porous/cellular materials can be made to exceed those of the parent materials provided the pore surface elastic parameters satisfy certain conditions. These stiff nano-porous materials herald a radical breakthrough in sandwich-type construction.

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Decomposition yields of tetracycline hydrochloride (TC.HCl) and chlorotetracycline hydrochloride (ClTC.HCl) in methanol solution saturated with Ar or N/sub 2/O were determined. Rate constants of the reaction esub(s)/sup -/ with some antibiotics were obtained. It was demonstrated by /sup 1/H NMR that the radical formed by degradation of 7-C-Cl group is recombined with the H atoms leading to ClTC.HCl being converted into tetracycline hydrochloride (TC.HCl).

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We summarize the predictions of different models for total {gamma}{gamma} cross-sections. The experimentally observed rise of {sigma}{sub {gamma}}{sub {gamma}} with s radical {sub {gamma}}{sub {gamma}}, faster than that for {sigma}{sub p-barp}, {sigma}{sub {gamma}}{sub p} is in agreement with the predictions of the Eikonalized Minijet Models as opposed to those of the Regge-Pomeron models. We then show that a measurement of {sigma}{sub {gamma}}{sub {gamma}} with an accuracy of < or approx. 8-9% (6-7%) is necessary to distinguish among different Regge-Pomeron type models (the different parameterisations of the EMM models) and a precision of < or approx. 20% is required to distinguish the predictions of the EMMs and of those models which treat 'photon like a proton', for the energy range 300< s radical{sub {gamma}}{sub {gamma}} <500 GeV. We further show that the difference in model predictions for ...

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The atmospheric chemical behaviour of 2H-Heptafluoropropane (CF[sub 3]CHFCF[sub 3], HFC-227) with respect to its rate and mechanism of degradation in the troposphere has been investigated. The rate coefficient for the reaction of HFC-227 with OH radicals has been determined in direct time resolved experiments using a combination of laser-pulse initiation and LIF. In the temperature range T=298-463 K the Arrhenius expression k(T)=(3.8[+-]0.8) 10[sup -13] exp(-1596[+-]77 K/T) cm[sup 3]/s, which corresponds to k (298 K) = (1.8[+-]0.3) 10[sup -15] cm[sup 3]/s, was found. The mechanism of the atmospheric degradation of HFC-227 has been investigated using both, laser-pulse initiated/time resolved and UV photolysis/FTIR product studies. It is concluded that the major carbonyl products are CF[sub 3]COF and CF[sub 2]O which result from the decomposition of the oxy radical CF[sub 3]CF(O)CF[sub 3] by C-C bound fission. The rate coefficient for this ...

International Nuclear Information System (INIS)

The reactions of tetraphenylphosphonium ion (Ar_4P"+) with esub(aq)"-, H atoms and OH radicals have been investigated. The absorption spectra of three transient species were obtained. Ar_4Psup(.) radicals formed by the reaction: Ar_4P"+ + esub(aq)"- #-># Ar_4Psup(.) have a maximum absorption at 305 nm [epsilon _3_0_5 = (9400 +- 300)dm"3mol"-"1cm"-"1] and decays by second-order kinetics with the rate constant 2k = (2.7 +- 0.4) x 10"9dm"3mol"-"1s"-"1. H atoms and OH radicals form transient adducts to the phenyl groups of the Ar_4P"+ ion with the rate constants of (1.5 +- 0.3) x 10"9 dm"3mol"-"1s"-"1 and (3.0 +- 0.3) x 10"9dm"3mol"-"1s"-"1, respectively. Both adducts have broad absorption spectra at 300 approximately 380 nm (lambdasub(max) = 340 nm) with the molar extinction coefficients epsilonsub(340) = 5400 +- 300 dm"3mol"-"1cm"-"1 for the H adduct and epsilonsub(340) = 3500 +- 200 dm"3mol"-"1cm"-"1 for the OH adduct. ...

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Gamma-irradiation of isolated rat liver mitochondria with up to 475 Gy leading to hydrated electrons (G = 1.9, corrected for reaction with solutes), 30 Gy leading to carbohydrate radicals, (G = 5.6), 100 Gy leading to superoxide radicals (G = 6.2), and 130 Gy leading to formate radicals (G = 6.2) showed no effects on the rate of oxygen uptake in various respiratory states, the respiratory control ratio, or the adenosine diphosphate to atomic oxygen ratio. Typical values were 0.020-0.100 nmol O/sub 2/ s/sup -1/ mg protein/sup -1/ for State 1 respiration, 0.25-0.33 nmol O/sub 2/ s/sup -1/ mg protein/sup -1/ for State 4 respiration and 0.65-1.10 nmol O/sub 2/ s/sup -1/ mg protein/sup -1/ for State 3 respiration. Typical respiratory control ratios ranged from 2.0-3.5 for succinate and 4.0-6.5 for a 1:1 glutamate: malate substrate mixture. Adenosine diphosphate to atomic oxygen ratios with succinate as substrate varied from 1.6 ...

UK PubMed Central (United Kingdom)

PurposeTo describe ocular findings for a 34-year-old man with chronic solar retinopathy using high-speed ultrahigh-resolution (UHR) optical coherence tomography (OCT).Full Text Available

UK PubMed Central (United Kingdom)

The cytogenetic findings were analysed in a series of 500 pregnancies in which chorionic villi sampling was performed. In all cases a direct method was used, karyotyping being successful in 481 cases...Full Text Available

Science.gov (United States)

... of the utility of the terminal outcomes, ... Other stochastic topics, such as random walks, branching ... find special uses, particularly in queueing theory ...

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...Surface Aerators Products and Equipment Find and compare a variety of surface aerators products and equipment on the world's largest environmental industry portal. ...

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... Tunnel Composting Products and Equipment Find and compare a variety of tunnel composting products and equipment on the world's largest environmental industry portal. ...

CERN Document Server

Sumedh Anathpindika surveys astronomy in India and finds a lively and developing community as well as great public interest.

Science.gov (United States)

FEP polyethylene mechanical properties affected by UV. " Siloxane-modified materials resist AO. " Nonsilicone polymers attacked by AO ...

Energy Technology Data Exchange (ETDEWEB)

Various topics include: (1) direction finding, (2) range finding, (3) Doppler measurements, (4) construction of a receiver for radio interferometry, (5) mobile laser range finding system, (6) figure-and field parameter determination/geopotential, (7) dynamics of the Earth-Moon system, and (8) kinematics of geodetic point fields.

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FastBit is a software package designed to meet the searching and filtering needs of data intensive sciences. In these applications, scientists are trying to find nuggets of information from petabytes of raw data. FastBit has been demonstrated to be an order of magnitude faster than comparable technologies. In this brief report, we highlight how we work with a visualization team, a network security team and a DNA sequencing center to find the nuggets in their data.

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To assess the potential of CT in evaluating the histological severity of acute appendicitis in comparison with surgical and pathological findings. The CT images of 75 patients with surgically proven appendicitis, including 10 cases of catarrhal, 34 of phlegmonous, and 31 of gangrenous appendicitis, were retrospectively analyzed for the following five CT findings: hazy periappendiceal densities, enlarged appendix, increased enhancement of the appendiceal wall, increased enhancement of the periappendiceal intestinal wall, and deficiency of the appendiceal wall. By comparing all the CT findings and the pathological severity of appendicitis (catarrhal, phlegmonous, and gangrenous), the prevalence of the five CT findings was calculated for each pathological category. Abnormal CT findings were noted in only one case of catarrhal appendicitis. Increased enhancement of the appendiceal wall ...

International Nuclear Information System (INIS)

The production of ozone in a negative corona discharge fed by carbon dioxide with embedded traces of oxygen and water has been studied. The presence of traces of oxygen in both pure and dry CO_2 leads to an increase in nascent ozone concentrations. In contrast, traces of water vapour (0-800 ppm) are shown to rapidly suppress ozone concentrations with the largest decreases being observed at lowest gas pressures in the discharge (300 Torr). The presence of water vapour did not considerably affect the electrical properties of negative dc corona suggesting that a chemical process is responsible for the ozone loss. We have shown that the addition of water up to a concentration of 1500 ppm has only a marginal effect on the processes of ozone formation but the catalytic cycle of ozone destruction involving OH radicals can be the reason for observed decrease in the total ozone concentration with increasing water concentration.

British Library Electronic Table of Contents (United Kingdom)

Women treated of localised stages of cervix cancer have a very good prognosis. But do health care professionals have a tendency to underestimate the potential need for rehabilitation of this group? To be able to answer this question this study aimed to develop knowledge concerning these women's own perception of their health during a long period after surgical cancer treatment. A total of 398 women who underwent radical hysterectomy in the period from the 1 January 1983 to 31 December 2000 participated in the study at Aarhus University Hospital, Skejby in Denmark 2001-2003. All patients initially filled in an internally validated questionnaire. Subsequently a sample of 100 women filled in the questionnaires Short Form -36 and Sense of Coherence to evaluate their self-reported health. Analy...

Science.gov (United States)

uv irradiation (365 nm) of air-saturated methanol solutions of 20 drugs absorbing in the 300 to 400 nm region gave rise to oxygen uptake, as determined with a polarographic oxygen electrode. The drugs were tested for photosensitizing capability by either a Type I (free radical) or a Type II (single molecular oxygen) mechanism. This testing was done by the inclusion of either acrylamide or 2,5-dimethylfuran in the irradiated drug solution, with observation of the subsequent polymerization or oxidation, respectively. Phenothiazine and thiazide derivatives appear capable of photosensitization by both mechanisms; promethazine, trifluoperazine, and furosemide show relatively high reactivity. Diazepam (weak), hexachlorophene, aminacrine, pyrilamine, tetracycline, demeclocyline, quinine, and anthracene (strong) react only by a Type II mechanism, with a photosensitizing efficiency increasing in the order given. A correlation appears to exist with reports of in vivo ...

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A three-dimensional, continuous-energy, coupled neutron-gamma Monte Carlo model of the advanced neutron source (ANS) final preconceptual reference core design has been developed using MCNP Version 3b. This model contains the reactor core with control rods, the heavy-water reflector tank with shutdown rods and representative beam tubes, and the outer light-water poor. Eighty homogenized fuel zones per fuel element are used to represent the radical and axial {sup 235}U fuel grading. This model is the most sophisticated, physically accurate reactor physics model of the ANS currently available. The purpose of this summary is to demonstrate the MCNP methods and applications for the ANS.

Energy Technology Data Exchange (ETDEWEB)

New market based approaches are becoming increasingly important as instruments of environmental policy. The two main market approaches, i.e., transferable pollution permits (experimented in America), and 'green' energy surcharges (European philosophy), are described and discussed. An analysis of information on their state of implementation shows that, in the case of the former method, the greatest sources of difficulty arise in the determination of acceptable ceiling levels of emissions, in the distribution of permits among the various polluting firms, and in the legality of granting rights to pollute. Instead, the European experience has evidenced that energy surcharges motivated by environmental policy cannot have an appreciable positive impact on consumers or the economic system in general unless they are accompanied by well defined measures geared towards the promotion or creation of alternative solutions such as to stimulate radical change in ...

British Library Electronic Table of Contents (United Kingdom)

The degradation of irradiated human insulin in aqueous solutions was investigated in order to protect the protein against ionizing radiation. The influence of the drug concentration, excipients and irradiation temperature were studied.Aqueous solutions at pH 2 were irradiated by gamma rays or by accelerated electrons. Two different high-performance liquid chromatography (HPLC) methods were used: reverse-phase high-performance liquid chromatography (RP-HPLC)/UV and size exclusion liquid chromatography (SEC/UV) to investigate both the fragmentation and the formation of higher molecular weight proteins.In solution without excipients irradiated at ambient temperature at 10kGy, the loss of human insulin is almost complete. Addition of radio-protecting excipients (free radicals scavengers) and c...

International Nuclear Information System (INIS)

Childhood cancer survivors at highest risk of developing a secondary malignancy are those with hereditary retinoblastoma. The majority of such secondary cancers will be sarcomas, most commonly of bone. One-third of these occur outside a typical radiation field, commonly in an extremity. Bone sarcoma is also the most commonly reported secondary cancer to develop among survivors of Ewing's sarcoma. In this group, radiation doses greater than 60 Gy as well as alkylating agent chemotherapy have been identified as contributors to the increased risk. The prognosis for patients with a secondary sarcoma has been poor, with few cures reported to date. However, an aggressive, combined modality approach, including radical resection, postoperative radiation, and adjuvant chemotherapy, may improve the survival rate.

British Library Electronic Table of Contents (United Kingdom)

ObjectivesTo assess the influence of epigallocatechin-3-gallate (EGCG) on the efficacy of ionizing radiation on prostate cancer cells because of the increased use of dietary interventions, especially by patients with prostate cancer. Radiotherapy is used to treat localized prostate cancer. Some people consume green tea (EGCG) as a chemopreventive agent against prostate cancer. Green tea can act as an antioxidant and induce superoxide dismutase enzymes, which could scavenge the free oxygen radicals generated by radiotherapy. MethodsProstate cancer cell line DU145 cells were treated with EGCG or radiotherapy, or both. Cell death was assessed using trypan blue cell counting, and apoptosis was confirmed by assessing poly (adenosine phosphate ribose) polymerase cleavage. The antioxidant potenti...

Energy Technology Data Exchange (ETDEWEB)

The primary charge separation in photosynthetic bacteria generates a dimeric bacteriochlorophyll (BChl) cation and a bacteriopheophytin (BPheo) anion which lie within close proximity of each other (approx. 10 A). The two radicals also lie within van der Waals contact on opposite sides of a lone BChl bridging molecule. Spectral changes in the red (Q/sub y/) band of the bridge BChls have been observed on picosecond time scales following excitation of the reaction center (RC) and have been variously attributed to the formation of a BChl anion, to a charge-transfer state, or to electrochromic effects. They present calculations here which suggest that electrochromic effects caused by the photogenerated cation and/or anion can rationalize the optical changes observed in the flash photolyses as well as in trapping experiments.

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Ionizing radiation has been used to treat poultry to remove harmful microorganisms, mainly Salmonella, which contaminates chicken, goose and other fresh and frozen poultry. This microorganism is sensitive to low dose radiation. Thus, irradiating these foods with doses between 1 to 7 kGy results in a large reduction of bacteria. Since it is necessary to determine whether irradiation has occurred and to what extend, this work studied the signal produced by ionizing radiation within the hard crystalline matrix of chicken`s bone to establish a control method. Chicken`s drumsticks were irradiated and bones separated from flesh were lyophilized and milled. ESR spectrum was then obtained. The ESR signal increased linearly with dose over the range 0.25 to 8.0 kGy. Free radicals evaluated during 30 days after irradiation showed stable in this period. (Author).

Science.gov (United States)

During this report period, we have obtained a model of montmorillonite clay, and this model has been of great assistance in visualizing how the chemistry of substrate molecules might be altered as it occurs on the surface of the clay. A stereochemical representation of this montmorillonite model is shown. Of particular significance, this model indicates that hydroxyl groups are located in the center of each siloxane ring on the surface of the montmorillonite clay. These hydroxyl groups might serve to bond substrate molecules to the surface of the clay. The next step in our systematic examination of the radical cation-initiated dimerization of plant monomers from the C{sub 6}-C{sub 3} pool of shikimic acid metabolites was to study the dimerization of cinnamic acid and its derivatives. In the next block of research, we examined the reaction of montmorillonite clay (K-10) with methyleugenol. 2 refs.

Energy Technology Data Exchange (ETDEWEB)

Here we report a new method for measuring the heterogeneous chemistry of submicron organic aerosol particles using a continuous flow stirred tank reactor. This approach is designed to quantify the real time heterogeneous kinetics, using a relative rate method, under conditions of low oxidant concentration and long reaction times that more closely mimic the real atmosphere. A general analytical expression, which couples the aerosol chemistry with the flow dynamics in the chamber is developed and applied to the heterogeneous oxidation of squalane particles by hydroxyl radicals (OH) in the presence of O2. The particle phase reaction is monitored via photoionization aerosol mass spectrometry and yields a reactive uptake coefficient of 0.51+-0.10, using OH concentrations of 1-7x108 molec cdot cm-3 and reaction times of 1.5+-3 hours. This uptake coefficient is larger than that found for the reaction carried out under high OH concentrations (~;;1x1010 molec cdot cm-3) and ...

International Nuclear Information System (INIS)

Background and purpose: A diagnosis of malignancy and its treatment is a very stressful time for patients and their families. This study was conducted to determine the impact of more intensive written information on patients' anxiety levels. The secondary aim was to determine the impact of this information on patients' satisfaction levels. Materials and methods: This prospective randomized trial consisted of patients with a pathological diagnosis of cancer having radical radiotherapy (RT). Patients were randomized to receive the more intensive information (including written information and a telephone call from the research nurse) or not to receive the more intensive information at the time of their initial consultation with the radiation oncologist. Study questionnaires measuring anxiety (STAI form) were completed prior to their first consultation (baseline) at the time of simulation (pre-RT) and at the completion of radiotherapy. A second questionnaire assessing ...

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Extensive research into the treatment and control of Volatile Organic Compounds (VOCs) from semiconductor industry manufacturing processes has identified the need for alternatives to existing combustion devices. Specifically, semiconductor manufacturing design is moving toward exploiting effective, small-scale, abatement control technologies for specific point-of-use (POU) waste streams associated with a particular component or manufacturing tool. The Silent Discharge Plasma (SDP) developed at Los Alamos National Laboratory is a nonthermal plasma technology created by a dielectric-ballasted electrical discharge. Influent gas-phase pollutants are destroyed in the reactor by the free radicals or electrons generated by the plasma. This paper examines the potential for SDP to be used in niche circumstances for POU control of VOC exhaust streams specific to the semiconductor industry. A sensitivity analysis is presented, showing how SDP cost of ownership is affected by ...

International Nuclear Information System (INIS)

A study was conducted to determine the feasibility and the opportunity of photochemical pretreatment on the biodegradation and detoxification of Methyl Tert Butyl Ether (MTBE), Ethyl Tert Butyl Ether (ETBE) and Tert Amyl Methyl Ether (TAME), the most common oxygenates used as octane enhancers in unleaded gasoline. The production, storage, uses and disposal of oxygenates result in an unknown amount of groundwater pollution. Because of their high solubility, MTBE, ETBE and TAME are detected in large portions in saturated zones of aquifers. The biodegradation of these oxygenates is difficult and slow, and information regarding their biodegradability is scarce. Photo-decomposition of oxidants under appropriate UV radiation has been shown to be very effective because the hydroxyl radicals produced possess high oxidation potential. In this study, the H_2O_2/UV process was used to generate hydroxyl radicals. Maximal oxygenates transformation was ...

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The most common causes of tracheobronchial foreign bodies are peanuts in children, and meat and dentures in adults. The most common causes of esophageal foreign bodies are coins in children and meat in adults. It is passable to diagnose a foreign body by visualization on a chest radiograph, if the foreign bodies are radio opaque. However, if the foreign bodies are radiolucent and the patients do not remember the history of aspiration, it is important to evaluate CT findings for foreign bodies and their complications. We describe the CT findings of various thoracic foreign bodies in children and adults.

UK PubMed Central (United Kingdom)

The ultrastructure of conjunctival melanocytic lesions in 49 patients was evaluated to find significant differences between benign and malignant cells. The patients studied included 9 with benign epithelial...Full Text Available

UK PubMed Central (United Kingdom)

Background/Objective:Tarlov cysts or spinal perineurial cysts are uncommon lesions. These are mostly incidental findings on magnetic resonance imaging or myelograms. The...Full Text Available

International Nuclear Information System (INIS)

We report a 55-year-old woman with coccydynia due to a sacral mass. The histological diagnosis was haemangioma. The MRI findings and the unusual location of this lesion are discussed. (orig.)

UK PubMed Central (United Kingdom)

The success of monoclonal antibodies in clinical practice is dependent on good design. Finding a suitable target is the most important part as other properties of the antibody can be altered by genetic...Full Text Available

UK PubMed Central (United Kingdom)

Purpose. To describe the characteristics of idiopathic macular holes (MH) on optical coherence tomography (OCT) and correlate OCT with clinical assessment. Design....Full Text Available

UK PubMed Central (United Kingdom)

ObjectiveNeuralgic amyotrophy (NA) is a distinct clinical syndrome that is characterized by the acute onset of shoulder and arm pain, weakness, and sensory loss. The purpose of this...Full Text Available

Wastenet

... Waste Collection Systems Products and Equipment Find and compare a variety of waste collection systems products and equipment on the world's largest environmental industry portal. View product ...

Science.gov (United States)

Sep 18, 2007 ... Lightweight structural aerogels would find applications as a component of composite sandwich panels that are both lightweight and insulating ...

International Nuclear Information System (INIS)

The MRI's of 16 patients with either primary or secondary lymphatic disorders are evluated and the findings are compared to those from lymphangioscintigraphy or surgery. (author).

Science.gov (United States)

You can find a discussion of time travel and Tipler's cylinder at this site: http://www.star-names.freeserve.co.uk/travel.htm ...

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... Geothermal Energy Equipment in Finland on Environmental Expert Find and compare a variety of geothermal energy equipment in finland on the world's largest environmental ...

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... Fuel Cell Technologies Equipment on Environmental Expert Find and compare a variety of fuel cell technologies equipment on the world's largest environmental industry portal. View ...

UK PubMed Central (United Kingdom)

The cause of the female urethral syndrome has previously been obscure, as it has been associated by definition with a lack of objective findings but a plethora of subjective complaints of retropubic...Full Text Available

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... Corrosion Inhibitors Equipment on Environmental Expert Find and compare a variety of corrosion inhibitors equipment on the world's largest environmental industry portal. View ...

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... Biogas Analyzers Equipment on Environmental Expert Find and compare a variety of biogas analyzers equipment on the world's largest environmental industry portal. View ...

International Nuclear Information System (INIS)

We illustrate serial HRCT findings over a 16-month period in a 35-year-old woman who had ingested paraquat. Initial areas of ground-glass opacity changed into areas of multiple air cysts on follow up scan obtained five months after ingestion. A further follow-up scan obtained 16 months after ingestion showed improvement, with increased lung volume and normalized lung architecture.

Energy Technology Data Exchange (ETDEWEB)

An effort to determine the effect of restructuring on prices finds that, on average, prices for industrial customers in restructured states were lower, relative to predicted prices, than prices for industrial customers in non-restructured states. This preliminary analysis also finds that these price changes are explained primarily by high pre-restructuring prices, not whether or not a state restructured. (author)

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The intrasphenoid form of basal cephalocele is uncommon. We describe the clinical, CT and MRI findings in two cases presenting in middle age with persistent cerebrospinal fluid rhinorrhoea. Emphasis is placed upon the imaging findings which aid in discrimination of intrasphenoidal cephalocele from more common causes of a sphenoid sinus mass. (orig.)

CERN Document Server

Two-dimensional generalization of the original peak finding algorithm suggested earlier is given. The ideology of the algorithm emerged from the well known quantum mechanical tunneling property which enables small bodies to penetrate through narrow potential barriers. We further merge this ``quantum'' ideology with the philosophy of Particle Swarm Optimization to get the global optimization algorithm which can be called Quantum Swarm Optimization. The functionality of the newborn algorithm is tested on some benchmark optimization problems.

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Between October 1990 and March 1991, 8 patients with cystic lesions in the region of the posterior bladder wall, the seminal vesicles and the prostate were examined by MRI. In all cases there was accurate characterisation of the lesion and of its anatomy. In 3 patients with abnormalities in the retrovesical space there was very good agreement with the operative findings. 4 patients were treated conservatively. In these patients there was good agreement with the findings on cystoscopy, CT and sonography. (orig.).

Energy Technology Data Exchange (ETDEWEB)

This document contains responses and planned actions that address the findings of the Tiger Team Assessment of Brookhaven National Laboratory, June 1990. In addition, the document contains descriptions of the management and organizational structure to be used in conducting planned actions, root causes for the problems identified in the findings, responses, planned actions, schedules and milestones for completing planned actions, and, where known, costs associated with planned actions.

International Nuclear Information System (INIS)

The work presented here demonstrates the ability of proton-transfer-reaction mass spectrometry (PTR-MS) to perform fast-response measurements of volatile organic compounds (VOCs) (including methanol, acetonitrile, acetaldehyde, acetone, PAN-type compounds, alpha- and beta-pinene, nopinone and pinonaldehyde) at the pptv level and its versatile applicability in the field of environmental trace gas analysis. Laboratory and field experiments including various calibration techniques and intercomparisons with other measurement techniques such as gas chromatography, atmospheric pressure chemical ionization and Fourier transformation infrared spectroscopy were performed providing a first characterization of the PTR-MS instrument performance (sensitivity, detection limit, precision, accuracy). Typically a detection limit (S/N=2) of 50 pptv for a 10 s signal integration time, a precision of 5 % and an accuracy in the range between 10 and 25 % were observed. Due to its compactness and ruggedness ...

Science.gov (United States)

The effects of the structure of a carboxylic acid on the processes of oxidation and reduction of iron ions in irradiated aqueous solutions were directly observed during irradiation. The solutions contained the mono- or dicarboxylic acid, H/sub 2/SO/sub 4/, Fe(NH/sub 4/)/sub 2/(SO/sub 4/)/sub 2/ and O/sub 2/. Th e ferrous oxidation was rather independent of the acid and its concentration, but the reduction of ferric was possible in the presence of formic, oxalic, or valeric acid only. The radical formed from the valeric acid acts similar to those formed from hydrocarbons. The G-values of oxidation and reduction of the iron ions were established. The molar extinction coefficients for oxalic and malonic complexes of ferric ions were determined. (auth)

Energy Technology Data Exchange (ETDEWEB)

For the coal liquefaction, improvement of liquefaction conditions and increase of liquefied oil yield are expected by suppressing the recombination through rapid stabilization of pyrolytic radicals which are formed at the initial stage of liquefaction. Two-stage liquefaction combining prethermal treatment and liquefaction was performed under various conditions, to investigate the effects of reaction conditions on the yields and properties of products as well as to increase liquefied oil yield. Consequently, it was found that the catalyst contributes greatly to the hydrogen transfer to coal at the prethermal treatment. High yield of n-hexane soluble fraction with products having low condensation degree could be obtained by combining the prethermal treatment in the presence of hydrogen and catalyst with the concentration of slurry after the treatment. This was considered to be caused by the synergetic effect between the improvement of liquefaction by suppressing ...

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Using a series of polycations synthesized by atom transfer radical polymerization (ATRP), we investigate the effects of the polymer charge density and hydrophobicity on salt-induced interdiffusion of polymer layers within polyelectrolyte multilayer (PEM) films. Polycations with two distinct hydrophobicities and various quaternization degrees (QPDMA and QPDEA) were derived from parent polymers of matched molecular weights poly(2-(dimethylamino)ethyl methacrylate) (PDMA) and poly(2-(diethylamino)ethyl methacrylate) (PDEA) by quaternization with either methyl or ethyl sulfate. Multilayers of these polycations with polystyrene sulfonate (PSS) were assembled in low-salt conditions, and annealed in NaCl solutions to induce layer intermixing. As revealed by neutron reflectometry (NR), polycations with lower charge density resulted in a faster decay of film structure with distance from the substrate. Interestingly, when comparing polymer mobility in QPDEA/PSS and QPDMA/PSS ...

International Nuclear Information System (INIS)

The atomic explosions in Hiroshima and Nagasaki made the name radiation itself become a nightmare. Notwithstanding this, radiation continued to serve the mankind specially in diagnosis of several human diseases and in the treatment of intractable malignancies. With their latest research tools biologists have now shown a significant shift in the earlier paradigm; even the concept that radiation initiates cancer appears to be no longer tenable. On the contrary, selective radiation doses inhibit growth of cancer cells and radiation in combination with many chemotherapeutic drugs, radiosensitizing chemicals and/or hyperthermia, is emerging as a new modality for cancer treatment which offers high therapeutic advantages. In addition, the deleterious effects of radiation can now be strategically counter poised by the use of many drugs and chemicals. This has been possible by the newer insights gained in the mechanism of biological effects of radiation. The fate of radiation-induced free ...

International Nuclear Information System (INIS)

Radiation damage studies have been carried out on undoped and CrO_4"2"- doped potassium and ammonium alums. The optical absorption bands observed around 27100 and 36500 cm"-"1 before irradiation have been attributed to the transitions t_1 #-># e and t_1 #-># t_2, on the basis of Ball-hausen and Liehr scheme. On prolonged X-irradiation, these bands disappear in both the alums and three new bands seem to grow in ammonium alum while only two new bands could be seen in potassium alum. EPR studies at RT reveal that there are two lines at g = 2.004 and g = 2.010 in ammonium alum and only one line at g = 2.004 in potassium alum. Besides these two nearly isotropic lines, there is a set of lines around g = 1.95 in both the alums. Correlating the optical and EPR studies it is concluded that SO_3"- and O_3"- centres have formed on X-irradiation in ammonium alum while only SO_3"- seems to have formed in potassium alum. The most important feature is the formation of a new paramagnetic ...

Energy Technology Data Exchange (ETDEWEB)

The transients involved in the reaction of tetracycline (TC) with reducing radicals such as e{sub aq}{sup -}, (CH{sub 3}){sub 2}COH and CO{sub 2}{sup .-}have been characterized by the pulse radiolysis technique. The semi-reduced species formed ({lambda}{sub max} = 630 nm, {epsilon} 3.4 x 10{sup 3} dm{sup 3} mol{sup -1} cm{sup -1}) has been found to be a strong reductant with reduction potential lying in the range -0.450 to -1.40 V vs NHE. TC reacts with e{sub aq}{sup -} at diffusion-controlled rates and the rate constant, depending upon the ionic form of TC existing at a particular pH, varies from 1.2 x 10{sup 10} to 2.8 x 10{sup 10} dm{sup 3} mol{sup -1} s{sup -1}. Based on these results a plausible site of electron addition has been suggested. Reaction of H atoms with TC gives rise to a transient which exhibits spectral and kinetic features different from that of semi-reduced species. (author).

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The phenomenology of wire chamber aging is discussed and fundamentals of proportional counters are presented. Free-radical polymerization and plasma polymerization are discussed. The chemistry of wire aging is reviewed. Similarities between wire chamber plasma (>1 atm dc-discharge) and low-pressure rf-discharge plasmas, which have been more widely studied, are suggested. Construction and use of a system to allow study of the plasma reactions occurring in wire chambers is reported. A proportional tube irradiated by an {sup 55}Fe source is used as a model wire chamber. Condensable species in the proportional tube effluent are concentrated in a cryotrap and analyzed by gas chromatography/mass spectrometry. Several different wire chamber gases (methane, argon/methane, ethane, argon/ethane, propane, argon/isobutane) are tested and their reaction products qualitatively identified. For all gases tested except those containing methane, use of hygroscopic filters to ...

International Nuclear Information System (INIS)

The manufacture and use of wood/plastic composite (WPC) as an example of wood matrix and wood sawdust/plastic composites (SDP) as an example of plastic matrix are reviewed. The raw material for WPC are mostly vinyl monomers, particularly methyl methacrylate and styrene. The reaction in WPC polymerization is radical polymerization. Researches on the radiation sources mostly resulted in gamma-ray. Electron beam can be applied only to thin products. The future use of WPC may be for furnitures, sporting goods, decorative parts and the like. Vital study on the reduction of manufacturing costs is required, for example, the improvement of reaction and the adoption of continuous process must be considered. The raw materials for SDP are wood sawdust, vinyl monomer (mostly methyl methacrylate) and resins. Electron beam accelerators are the most preferable radiation source because of its high efficiency and safe operation. SDP shows good forming property. The most preferable ...

DEFF Research Database (Denmark)

We present a new photonic technology and demonstrate that it allows for precise immobilisation of biomolecules to sensor surfaces. The technology secures spatially controlled molecular immobilisation since immobilisation of each molecule to a support surface can be limited to the focal point of the ultraviolet (UV) beam, as small as a few micrometers. We can immobilise molecules according to any pattern, from classical microarrays to diffraction patterns creating unique watermarking safety patterns. Given that suitable protein markers exists for all relevant diseases it is entirely feasible to test for a range of disease indicators (antigens and other markers) in a single test. Few micrometer spotsize allows for a virtually unlimited number of protein spots in a multipotent microarray. This new technology produces radically new photonics based microarray sensing technology and watermarking and has clear potential for biomedical, bioelectronic, surface chemistry, ...

International Nuclear Information System (INIS)

In 1981, the German Society of Pediatric Oncology initiated a multi-institutional study for the treatment of Ewing's sarcoma. The protocol (Cooperative Ewing's Sarcoma Study, CESS 81) consisted of four courses of a four-drug-regimen (VACA), each course taking nine weeks. Local therapy (radical surgery or resection plus irradiation or radiotherapy alone) was performed after the second course. The results of CESS 81 can be summarized as follows: VACA-chemotherapy is effective in controlling systemic disease. Initial tumor mass and response to initial chemotherapy are of major prognostic value for local control and survival. Permanent local control is a problem, especially in irradiated patients. The high local failure rate in irradiated patients in CESS 81 could be attributable to the following reasons: Late start of local therapy (after 18 weeks of chemotherapy), uneven distribution of prognostic parameters: Large tumors were more often irradiated than operated, ...

Energy Technology Data Exchange (ETDEWEB)

Recent organic geochemical studies differ radically in their interpretation of the origin of the Gulf coast oils. However all studies since (and including) Thompson, et al. 1989, emphasize the considerable geographic variation in genetic oil types and are in generalized agreement as to the genetic oil types present and their spatial and stratigraphic relationships. In particular it is accepted that the Gulf rim (both north and south) is encircled by a ring of Mesozoic carbonate-sourced oils and that there is also at least one major deep water trend of carbonate-sourced oils in the northern Gulf. It is also generally agreed that many of the Gulf rim oils are of Oxfordian-Kimmeridgian age, though some, like the Sunniland oils of Florida, are of lower Cretaceous origin. Major disagreement still occurs over the sources of the Louisiana offshore oils and onshore Wilcox reservoired oils. One {open_quotes}school of thought{close_quotes} assigns all these oils to Mesozoic ...

International Nuclear Information System (INIS)

Using the ammonia (NH3) plasma generated by a helical antenna surrounded by two magnetic coils, the transition of the discharge mode from low-density plasma to high-density one was observed. At the transition, the emission intensities from the H atoms and NH radicals especially increased in the optical emission spectroscopy, while the intensities of the other emission lines also increased abruptly. The nitridation of gallium arsenide (GaAs) surface was performed using the high-density NH3 plasma, and the properties of the nitrided surface layer were compared with those nitrided by high-density N2 plasma using the same apparatus. From the spectroscopic ellipsometry measurements, the thickness of the nitrided layer was estimated to be 16-18 nm, while that by N2 was 3-4 nm. From the Ga 3d spectra, the contamination with oxygen in the nitridation layer by NH3 plasma was less than that by N2 plasma.

Energy Technology Data Exchange (ETDEWEB)

In order to investigate the effect of humidity on laminar burning velocity(S), the effect of humidity on the combustion reaction and radiation intensity was studied, taking account of dilution gases such as CO/sub 2/ and Ar which has the approximately identical characteristics to exhaust gas circulation(EGR) gas used to prevent NOx discharge from engines. According to the heat reaction theory, mean specific heat(C) of mixture, mean molecular weight(M) and adiabatic flame temperature(T) etc. were said to affect S but from experimental results, the effect of M and C could be ignored, compared with the effect of T. The relationship between S and H/sub 2/O, Ar of CO/sub 2/% in mixture of diluted gases was clarified. The effect of H/sub 2/O on S was mainly caused by changes of T. The effect of radical C/sub 2/, CH and OH on radiation intensity was similar to that of H/sub 2/O and Ar and the effect of H/sub 2/O on combustion was found only to be the physical effect. (10 ...

Energy Technology Data Exchange (ETDEWEB)

Ionising radiation induces stable free radicals in chicken bones and in the shell of chicken eggs which can be detected, by the electrons spin resonance (ESR) technique, well beyond the shelf-life of the food and can be used for dosimetry. The method usually adopted to evaluate ``a posteriori`` the dose given during the ionising radiation treatment of food, is the dose additive method. To assess the dose, the ESR signal amplitude of the irradiated food (bone or egg shell in the present case) is measured and then the dose-effect relationship is obtained by re-irradiating the sample with some additive doses (usually of 1 kGy). The dose-effect curve is back-extrapolated and the initial given dose determined. At the Istituto Superiore di Sanita (ISS), Rome, Italy, a research programme was approved two years ago aimed to, (1) study new methodological approaches for ESR dose assessment, and (2) analyse the factors which may influence the ESR readout of irradiated chicken ...

International Nuclear Information System (INIS)

Production of ozone and OH radical is required to advance the plasma chemical reactions in the NOx removal processes for combustion gas treatment. The corona discharge to the water surface is expected to induce the good conditions for the proceeding of the NO oxidation and the NO_2 dissolution removal into water. In order to get the fundamental data of the corona discharge over the water surface, the positive and negative V-I characteristics and the ozone production were measured with the multi needle and the saw-edge type of the discharge electrodes. The pulse corona characteristics were also measured with some different waveforms of the applied pulse voltage. The experiments were carried out under the atmospheric pressure and room temperature. Both the DC and the pulse corona to the water surface showed a stable and almost the same V-I characteristics as to plate electrodes though the surface of water was waved by corona wind. The positive streamer corona showed ...

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The rate coefficients for the reactions of OH radical with CH3Br and CH2Br2 were measured as functions of temperature using the laser photolysis - laser induced fluorescence method. This data was incorporated into a semiempirical model (Solomon et al., 1992) and a 2D model to calculate the steady-state ozone depletion potentials (ODP) and atmospheri lifetimes, tau, with greatly improved accuracy as compared to earlier studies. The calculated ODPs and tau are 0.65 and 1.7 years and 0.17 and 0.41 years for CH3Br and CH2Br2, respectively, using the semiempirical model. These lifetimes agree well with those calculated using a 2D model. This study better quantifies the ODPs and tau of these species which are needed inputs for discussion of possible regulation of human emissions currently under international considerations. 29 refs.

British Library Electronic Table of Contents (United Kingdom)

Summary The antioxidant properties and toxicity profile of roasted noni (Morinda citrifolia L.) leaf infusion were evaluated. The 2,2-diphenylpicrylhydrazyl (DPPH) radical scavenging activity was greater than green tea infusion (81.6 +- 0.9% vs. 57.5 +- 1.8%, P < 0.001). The mean quercetin and kaempferol contents of roasted noni leaf infusion, as prepared by the consumer, were 0.24 +- 0.01 and 0.14 +- 0.01 mg mL-1, respectively. Tannic acid content was 10 +- 1 mg mL-1. The infusion was non-mutagenic in the reverse mutation test in Salmonella typhimurium and did not induce primary DNA damage in E. coli PQ37. Further, no significant primary DNA damage was induced by 5,15-dimethylmorindol, which was the only detectable anthraquinone in noni leaves. The infusion was not cytotoxic in the 24 h b...

Energy Technology Data Exchange (ETDEWEB)

A range of additives has been developed for enhancing grafting yields in a variety of systems initiated by ionizing radiation. Cellulose has been adopted as the predominant naturally occurring model backbone polymer in these studies because of its structural relationship to wood which is the reference substrate for the work reported in the related second part of this paper concerning composites. Some experiments have been performed with the other major naturally occurring polymer, wool. For comparison purposes with synthetic materials, some studies have also been performed with polypropylene as trunk polymer. Styrene has been used as a predominant monomer in grafting with some experiments utilizing the acrulates like methyl methacrylate. The role of solvent in grafting has been evaluated. UV has been used as initiator to replace ionizing radiation for certain experiments. The additives used were mineral acids, lithium salts, multifunctional acrylates and their methacrylate analogues, ...

Energy Technology Data Exchange (ETDEWEB)

The atmospheric chemical behaviour of 1,1,1,2-tetrafluoroethane (CF{sub 3}CFH{sub 2}, HFC-134a) with respect to its rate and mechanism of degradation in the troposphere has been investigated. The rate coefficient for the reaction of (1a) CF{sub 3}CFH{sub 2}+OH{yields}CF{sub 3}CFH+H{sub 2}O has been determined in direct time-resolved experiments using laser-pulse initiation and laser long-path absorption. A value of k{sub 1a}=(4.6{+-}0.5).10{sup -15} cm{sup 3}/s at T=295 K has been found. The ratio of the rate coefficients for the reactions of the CF{sub 3}CFHO-radical with O{sub 2}, (4) CF{sub 3}CFHO+O{sub 2}{yields}CF{sub 3}CFO+HO{sub 2}, and C-C bond fission, (5) CF{sub 3}CFHO+M{yields}CFHO+CF{sub 3}+M, for T=295 K and p{sub total}=50 mbar (O{sub 2}) has been obtained to be k{sub 4}/(k{sub 5}[M])=1.5.10{sup -19} cm{sup 3}, with the individual values being k{sub 4}=2.7.10{sup -15} cm{sup 3}/s and k{sub 5}[M]=1.8.10{sup 4} s{sup -1}. The mechanism of the ...

Energy Technology Data Exchange (ETDEWEB)

X-ray irradiation-induced paramagnetic radicals in rare earth (Ln) ion-doped glaserite and Ln ion-doped langbeinite were studied by means of ESR technique, aiming at developing the highly sensitive sensor for an ESR dosimetry. The samples were prepared by two kinds of procedures as follows. In one process, the glaserite (K{sub 3}Na(SO{sub 4}){sub 2}) matrix or the langbeinite (K{sub 2}Mg{sub 2}(SO{sub 4}){sub 3}) matrix were synthesized by heating the mixture of K{sub 2}SO{sub 4} and Na{sub 2}SO{sub 4} or the mixture of K{sub 2}SO{sub 4} and MgSO{sub 4} at 1023 K for 1 hour in He flow. The matrices obtained were mixed well with a fixed amount of Ln{sub 2}(SO{sub 4}){sub 3} (Ln=La, Eu, Gd, Lu) powder and heated at 1023 K for 1 hour in He flow. In the other process, the homogeneous mixture of a fixed amount of K{sub 2}SO{sub 4}, Na{sub 2}SO{sub 4} and Ln{sub 2}(SO{sub 4}){sub 3} powders or a fixed amount of K{sub 2}SO{sub 4}, MgSO{sub 4} and Ln{sub 2}(S0{sub 4}){sub ...

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Macrocephaly was defined as a head measuring larger than 98th percentile. We have evaluated CT findings and head growth curves in 25 infants with large heads. Ten (40%) of 25 infants with large heads were normal developmentally and neurologically. Five (20%) of those were mentally retarded. The other 10 infants (40%) included hydrocephalus (4 cases), malformation syndrome (3 cases), brain tumor (1 case), metabolic disorder (1 case) and degenerative disorder (1 case). Their head growth curves were typed as (I), (II) and (III): Type (I) (excessive head growth curve to 2 SDs above normal); Type (II) (head growth curve gradually approached to 2 SDs above normal); Type (III) (head growth curve parallel to 2 SDs above normal). Ten of macrocephaly with normal psychomotor development were studied clinically and radiologically in details. They were all male. CT pictures of those showed normal or various abnormal findings: ventricular dilatations, wide ...

British Library Electronic Table of Contents (United Kingdom)

Ventricular septal defects can occur as part of other congenital cardiac malformations or as an isolated finding. Aneurysms of the sinus of Valsalva are rare, most commonly involving the right or noncoronary sinuses. They can be congenital or acquired through infection, trauma, or degenerative diseases. They frequently co-exist with ventricular septal defects, aortic valve dysfunction, or other cardiac abnormalities. More commonly, sinus of Valsalva aneurysms are diagnosed after the clinical sequelae of rupture. Several etiologic factors may lead to the development of pathologic pericardial effusion and the detection of pericardial effusion was one of the first applications of echocardiography to gain widespread acceptance. We present a case of a chance finding of an aneurysm of the right ...

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In this work we examine a five-dimensional brane-world model with brane structure driven by a real scalar field. From the deformation of a kink-like defect we find a new class of brane solutions containing internal structures which have implications for the way the background space-time is constructed and the way its curvature behaves. Initially, for spin 0 scalar field, we find a zero mode which can be localized on the deformed brane. However, this result can change by the gravitational interaction with the brane internal structure. Analyzing the massive modes of the scalar field, using two different methods, we find resonance structures similar to those found in the study of gravity localization. The main objective here is to observe the contributions of the deformation procedure to the resonances and to the well known field localization methods.

CERN Document Server

We investigate the influence of the turbulence forcing on the mass distributions of gravitationally unstable cores by postprocessing data from simulations of non-selfgravitating isothermal supersonic turbulence with varying resolution. In one set of simulations solenoidal forcing is applied, while the second set uses purely compressive forcing to excite turbulent motions. From the resulting density field, we compute the mass distribution of gravitationally unstable cores by means of a clump-finding algorithm. Using the time-averaged probability density functions of the mass density, semi-analytic mass distributions are calculated from analytical theories. We apply stability criteria that are based on the Bonnor-Ebert mass resulting from the thermal pressure and from the sum of thermal and turbulent pressure. Although there are uncertainties in the application of the clump-finding algorithm, we find systematic differences in ...

International Nuclear Information System (INIS)

Ewing's sarcoma is a malignant bone tumor that can occur anywhere in the body, but it is most commonly observed in the long bones of the arms and legs, the pelvis and in the chest. The predominant sites of metastasis include the lung (38%), bone (including the spine; 31%), and the bone marrow (11%). Metastasis of Ewing's sarcoma to the central nervous system (CNS) is relatively rare, and most of the previous reports have demonstrated involvement of the bony calvarium or brain parenchyma. We describe here the imaging findings of dural metastasis of Ewing's sarcoma, and these imaging findings have not been previously reported on in the medical literature. In conclusion, dural metastasis of Ewing's sarcoma is very rare and its imaging characteristics are similar to those of a primary tumor, which mimic the findings of a schwannoma or meningioma. Despite its rarity, secondary Ewing's sarcoma may be included in the differential ...

British Library Electronic Table of Contents (United Kingdom)

The number of immigrants to Western Europe has been increasing, with immigration the subject of much controversy in contemporary Europe. In this article, we investigate the relationship between the size of the immigrant population, how natives perceive this size, and their anti-immigrant attitudes. We use data from the 2002/2003 European Social Survey covering 17 Western European countries, and we find that as a rule Western Europeans think that the immigrant population in their country is much larger than it actually is. The perceived size of an immigrant population has an impact on anti-immigrant prejudices, but the real size does not. Like many authors before us, we find that education reduces prejudice. However, we also find that around 10 percent of the total effect of education is a ...

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XMRV or xenotropic murine leukemia virus-related retrovirus, a recently discovered retrovirus, has been linked to both prostate cancer and chronic fatigue syndrome (CFS). Recently, the teams of Drs. Shyh-Ching Lo and Harvey Alter discovered the presence of sequences closely related to XMRV in the blood of 86.5% of patients with CFS [1]. These findings are important because since the initial discovery of XMRV in CFS, several studies have failed to find XMRV in specimens collected from CFS patients. While the current study also did not find XMRV in CFS, Lo et al. did detect sequences that belong to polytropic mouse endogenous retroviruses (PMV), which share considerable similarity with XMRV. Criteria for future studies that will help bring greater clarity to the issue of retroviral sequences in CFS are proposed below. PMID:21994623

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CT findings were compared retrospectively between 9 cases with malignant lymphoma of the anterior mediastinum and 8 cases with invasive thymoma. CT findings of malignant lymphoma were as follows: (1) The majority of the tumors were bilateral and extended beyond the anterior mediastinum to the other mediastinum compartments. (2) Their margin was either smooth or lobulated. (3) Their density was either homogeneous or heterogeneous. In the case with heterogeneous density, ring, triangle and/or band-like low density areas, just like interspace of fused lymph nodes, were demonstrated. Calcification or cysts could not be shown. (4) Patent inherent vessels without deviation were occasionally demonstrated running through the tumors. (5) The tumors faced and contacted widely to anterior chest wall and often pressed the lung laterally at the anterior parietomediastinal pleural reflection. (6) Pleural implants were not demonstrated. (author).

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Abstract Recent reports showed many patients with chronic fatigue syndrome (CFS) harbor a retrovirus, xenotropic murine leukemia-related virus (XMRV), in blood; other studies could not replicate this finding. A useful next step would be to examine cerebrospinal fluid, because in some patients CFS is thought to be a brain disorder. Finding a microbe in the central nervous system would have greater significance than in blood because of the integrity of the blood-brain barrier. We examined cerebrospinal fluid from 43 CFS patients using polymerase chain reaction techniques, but did not find XMRV or multiple other common viruses, suggesting that exploration of other causes or pathogenetic mechanisms is warranted. Ann Neurol 2011;

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of satellite, aircraft and ground-based observations. In ..... swarm traps by Utah Department of Food and Agriculture (DAF) personnel. Preliminary Results ..... the 150th anniversary of the book's publication and the 200th anniversary of Darwin's birth. ...... cold war submarine missions to find that Arctic Ocean ...

UK PubMed Central (United Kingdom)

Extending genome wide association analysis by the inclusion of gene expression data may assist in the dissection of complex traits. We examined piebald, a pigmentation phenotype in both human and Merino...Full Text Available

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The realization that there existed a G-protein coupled signal transduction mechanism developed gradually and was initially the result of an ill fated quest for uncovering the mechanism of action...Full Text Available

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BackgroundOlder adults may find it problematic to attend hospital appointments due to the difficulty associated with travelling to, within and from a hospital facility for the purpose...Full Text Available

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Aim:Report of 125 pediatric patients of empyema thoracis treated by open decortication, highlighting the presentation, delay in referral, operative findings, the response...Full Text Available

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In addition I have had many years been cooking for Scouts fund-raising events and a hundred and one sausage sizzles so I can find my way around a cooktop. ...

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Background:Smoking cessation is an important strategy for reducing the harmful effects of tobacco, particularly in the prevention of lung cancer; however, prospective data on the...Full Text Available

UK PubMed Central (United Kingdom)

Sex-related influences on pain and analgesia have become a topic of tremendous scientific and clinical interest, especially in the last 10 to 15 years. Members of our research group published...Full Text Available

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ObjectivesMild Cognitive Impairment (MCI) case-finding criteria have low specificity in general population studies. The present study retrospectively identifies cases...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundSynonymous sites are freer to vary because of redundancy in genetic code. Messenger RNA secondary structure restricts this freedom, as revealed by previous findings in...Full Text Available

UK PubMed Central (United Kingdom)

The past decade has seen rapid advances in the identification of associations between candidate genes and a range of common multifactorial disorders. This paper evaluates public attitudes towards the...Full Text Available

CERN Document Server

When it was first developed, the standard model predicted a collection of particles, and thanks to more and more powerful colliders, physicsists have been able to find them all except one: the Higgs-Boson.

CERN Document Server

We calculate the Bogolubov coefficients for a metric which describes the snapping of a cosmic string. If we insist on a matching condition for all times {\\it and} a particle interpretation, we find no particle creation.

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Mucopolysaccharidosis type IIIB (MPS IIIB; Sanfilippo syndrome type B) is a metabolic disorder with devastating clinical characteristics starting in early childhood and leading to premature death. A...Full Text Available

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...In your area Get connected Farmers & growers news Training & events Poultry (laying) Poultry production can be a profitable enterprise for organic farmers and eggs are ... To find out more about organic poultry production download our free comprehensive introductory guide: Organic poultry production - an introductory guide [PDF, ...

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Background and purposeRadial head fractures are common, and may be associated with other injuries of clinical importance. We present the results of a standard additional MRI scan...Full Text Available

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In this paper we report a case with primarily unspecific arthralgia after surgical therapy of hallux valgus deformity and consecutive reflex sympathetic dystrophy in which MR led to the diagnosis of Lyme disease. (orig.)

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This paper summarizes the findings for the African Region of the WPA Task Force on Steps, Obstacles and Mistakes to Avoid in the Implementation of Community Mental Health Care. We present an overview...Full Text Available

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To assemble into functional structures, biopolymers search for global minima through their folding potential energy surfaces to find the native conformation. However, this process can be hindered by...Full Text Available

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Membranous dysmenorrhea is an unusual clinical entity. It is characterized by the expulsion of huge fragments of endometrium during the menses, favored by hormonal abnormality or drug intake. This report describes a case with clinical, US, and MRI findings before the expulsion. Differential diagnoses are discussed. (orig.)

UK PubMed Central (United Kingdom)

CTX-M extended-spectrum β-lactamases (ESBLs) are increasingly prevalent worldwide among Escherichia coli bacteria, mostly in community-acquired urinary tract infections. Finding...Full Text Available

UK PubMed Central (United Kingdom)

Sentinel node biopsy is an alternative to elective neck dissection for the management of T1/T2 oral and oro-pharyngeal squamous cell carcinomas and is also finding application to head and neck cancer...Full Text Available

Medline Plus

... different personal wellness goals for you. HIV Health Management With a good medical team and a desire to reach wellness goals , people with HIV can have a virtually normal lifespan. Take the HIV Wellness Quiz Test your knowledge and find out where you need to learn ...

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BackgroundMany interventions found to be effective in health services research studies fail to translate into meaningful patient care outcomes across multiple contexts. Health services...Full Text Available

UK PubMed Central (United Kingdom)

Over the last several years, as cesarean deliveries have grown increasingly common, there has been a great deal of public and professional interest in the phenomenon of women ‘choosing’...Full Text Available