WorldWideScience
1

Expression of SV40 virus large T antigen by recombinant adenoviruses activates proliferation of corneal endothelium in vitro.  

UK PubMed Central (United Kingdom)

Infection with the Ad5-SVR4 virus was used to introduce the large T antigen encoding region of the SV40 virus into bovine and human corneal endothelial cells. Expression of large T antigen occurred...Full Text Available

1993-04-01

2

Transcription from the SV40 early-early and late-early overlapping promoters in the absence of DNA replication.  

UK PubMed Central (United Kingdom)

Transcription for a hybrid SV40 promoter-beta globin coding sequence recombinant initiates from both early-early (EE) and late-early (LE) SV40 start sites (EES and LES) in the absence of DNA replication....Full Text Available

1983-01-01

3

Inactivation of aflatoxin B1 by using the synergistic effect of hydrogen peroxide and gamma radiation  

Energy Technology Data Exchange (ETDEWEB)

Inactivation of aflatoxin B1 was studied by using gamma radiation and hydrogen peroxide. A 100-krad dose of gamma radiation was sufficient to inactivate 50 micrograms of aflatoxin B1 in the presence of 5% hydrogen peroxide, and 400 krad was required for total degradation of 100 micrograms of aflatoxin in the same system. Degradation of aflatoxin B1 was confirmed by high-pressure liquid chromatographic and thin-layer chromatographic analysis. Ames microsomal mutagenicity test showed loss of aflatoxin activity. This method of detoxification also reduces the toxin levels effectively in artificially contaminated groundnuts.

1989-02-01

4

Transformation and radiosensitivity of human diploid skin fibroblasts transfected with activated RAS oncogene and SV40 T-antigen  

Energy Technology Data Exchange (ETDEWEB)

Three normal human diploid cell strains were transfected with an activated Ha-ras oncogene (EJ ras) or SV40 T-antigen. Multiple clones were examined for morphological alterations, growth requirements, ability to grow under anchorage independent conditions, immortality and tumorigenicity in nude mice. Clones expressing SV40 T-antigen alone or in combination with ras protein p21 were significantly radioresistant as compared with their parent cells or clones transfected with the neo gene only. This radioresistant phenotype persisted in post-crisis, immortalized cell lines. These data suggest that expression of the SV40 T-antigen but not activated Ha-ras plays an important role in the radiosensitivity of human diploid cells. The radioresistant phenotype in SV40 T transfected cells was not related to the enhanced level of ...

1992-08-01

5

Radiation inactivation target size of rat adipocyte glucose transporters in the plasma membrane and intracellular pools  

Energy Technology Data Exchange (ETDEWEB)

The in situ assembly states of the glucose transport carrier protein in the plasma membrane and in the intracellular (microsomal) storage pool of rat adipocytes were assessed by studying radiation-induced inactivation of the D-glucose-sensitive cytochalasin B binding activities. High energy radiation inactivated the glucose-sensitive cytochalasin B binding of each of these membrane preparations by reducing the total number of the binding sites without affecting the dissociation constant. The reduction in total number of binding sites was analyzed as a function of radiation dose based on target theory, from which a radiation-sensitive mass (target size) was calculated. When the plasma membranes of insulin-treated adipocytes were used, a target size of approximately 58,000 daltons was obtained. For adipocyte microsomal membranes, we obtained target sizes of ...

1987-06-15

6

Significance of arming, potentiating and blocking factors as correlates the tumour-host interaction in the hamster SV40 system.  

UK PubMed Central (United Kingdom)

The study of blocking factors requires in vitro assay of cell mediated immunity that parallels the in vivo response. By microcytotoxicity testing, progressor and immune peripheral blood lymphocytes...Full Text Available

1975-12-01

7

A rapid and efficient method for region- and strand-specific mutagenesis of cloned DNA.  

UK PubMed Central (United Kingdom)

The single-stranded viral DNA of an M13 phage recombinant containing the early promoter region of SV40 was hybridized with linear, double-stranded replicative form DNA of a related M13 phage containing...Full Text Available

1982-01-01

8

UV inactivation: Combined effects of UV radiation and xenobiotics in two strains of Saccharomyces  

International Nuclear Information System (INIS)

The effects of eight chemicals on the inactivation rate of ultraviolet radiation on the colony building capabilities of two strains of Saccharomyces cervisae - a wild type strain and a mutant deficient in excision repair - were studied. The insecticide methoxychlor, the herbicide 2,4-dichlorophenoxyacetic acid, the fungicide pentachlorophenol and its metabolite tetrachlorohydroquinone, as well as the chemicals acrylonitrile and 2,3-dichloro-1-propene have no significant impact on the effects of UV radiation in Saccharomyces cerevisae. Depending on the concentration, trichloroethylene increases the sensitivity to UV radiation. The herbicide paraquat provides efficient protection against UV radiation at concentrations where a toxic effect cannot be observed even without UV. The results were rather similar for both strains. (orig.).

9

Wild-type p53 is not a negative regulator of simian virus 40 DNA replication in infected monkey cells.  

UK PubMed Central (United Kingdom)

To analyze the proposed growth-inhibitory function of wild-type p53, we compared simian virus 40 (SV40) DNA replication in primary rhesus monkey kidney (PRK) cells, which express wild-type p53, and...Full Text Available

1993-02-01

10

Plasmids for the cloning and expression of full-length double-stranded cDNAs under control of the SV40 early or late gene promoter.  

UK PubMed Central (United Kingdom)

Okayama and Berg (1) have recently described a technique for the high efficiency cloning of full-length dscDNAs. We have constructed eukaryotic expression vectors compatible both with this technique...Full Text Available

1983-10-25

11

Radiation inactivation target size of rat adipocyte glucose transporter  

Energy Technology Data Exchange (ETDEWEB)

In situ assembly states of rat adipocyte glucose transport protein in plasma membrane (PM) and in microsomal pool (MM) were assessed by measuring target size (TS) of D glucose-sensitive, cytochalasin B binding activity. High energy radiation inactivated the binding in both PM and MM by reducing the total capacity of the binding (B/sub T/) without affecting the dissociation constant (K/sub D/). The reduction in B/sub T/ as a function of radiation dose was analyzed based on classical target theory, from which TS was calculated. TS in the PM of insulin-treated adipocytes was 58 KDa. TS in the MM of noninsulin-treated and insulin-treated adipocytes were 112 and 109 KDa, respectively. With MM, however, inactivation data showed anomalously low radiation sensitivities at low radiation doses showing a shoulder in the semilog plots, which may be due to an interaction ...

1987-05-01

12

The effects of packaging materials on microbe population in irradiated traditional herbal medicines  

International Nuclear Information System (INIS)

Microbial population and moisture content of traditional herbal medicines contaminated with 3 kinds of aerobic microbes, packed in 5 kinds of plastic packaging materials, followed by irradiation at minimum dose of 5 kGy and stored for 6 months were investigated. The highest reduction of microbial counts during storage was observed on samples packed in polyethylene bags. All of packaging materials used were found to be impermeable to microbes and water vapour. Radiation and packaging materials used acted synergistically to inactivate microbes durind storage. The microbial counts decreased as much as 2 to 4 log cycles during storage. (author).

13

The effect of irradiation on packaging materials  

International Nuclear Information System (INIS)

Ionizing radiation, mainly in the form of #gamma#-rays from the radioisotope cobalt 60, is being used increasingly for the inactivation of contaminants in cosmetic and toiletry preparations. The treatment is applied to the product in its final pack, and therefore, it is important to recognize that the properties of the packaging materials could be affected, particularly if high radiation doses are used. The stability of a wide range of materials is discussed. The nature and extent of chemical and physical changes in plastics very much depends on the presence of antioxidants and other additives, and on the environmental conditions during irradiation. Some useful information is available from research into the use of radiation for the preservation of food - many films and laminates have been cleared for use in the United States. The low radiation doses used for the control of ...

16

Functional and physical molecular size of the chicken hepatic lectin determined by radiation inactivation and sedimentation equilibrium analysis  

Energy Technology Data Exchange (ETDEWEB)

Radiation inactivation and sedimentation equilibrium analysis were used to determine the functional and physical size of the chicken hepatic membrane receptor that binds N-acetylglucosamine-terminated glycoproteins. Purified plasma membranes from chicken liver were irradiated with high energy electrons and assayed for 125I-agalactoorosomucoid binding. Increasing the dose of ionizing radiation resulted in a monoexponential decay in binding activity due to a progressive loss of binding sites. The molecular mass of the chicken lectin, determined in situ by target analysis, was 69,000 +/- 9,000 Da. When the same irradiated membranes were solubilized in Brij 58 and assayed, the binding protein exhibited a target size of 62,000 +/- 4,000 Da; in Triton X-100, the functional size of the receptor was 85,000 +/- 10,000 Da. Sedimentation equilibrium measurements of the purified binding protein yielded a lower limit molecular weight of ...

1990-03-05

17

Mechanism of trypsin inactivation by intact Hymenolepis diminuta (Cestoda)  

International Nuclear Information System (INIS)

The mechanism of trypsin inactivation by intact Hymenolepis diminuta has been investigated by biochemical and autoradiographic methods. Although worms inactivate trypsin and chymotrypsin in vitro, no inactivation of other endoproteases (subtilisin, pepsin and papain) could be demonstrated. Trypsin inactivation, as demonstrated by macromolecular substrates (azoalbumin, hemoglobin and casein), could not be detected using low molecular weight synthetic substrates such as N-p-benzoyl-DL-arginine-p-nitroanilide (BAPA) or N-p-tosyl-L-arginine methyl ester (TAME). In addition, the kinetic parameters (K/sub m/ and k_3) for H. diminuta-inactivated trypsin, using BAPA as the substrate, were not different from those of the native enzyme. The number of active sites for both native and inactivated trypsin were determined by titration with p-nitro-phenyl-p'-guanidinobenzoate. ...

1979-01-01

18

Suicide of EMT-6 tumor cells by decays from radioactively-labelled sensitizer adducts  

International Nuclear Information System (INIS)

Nitroaromatic radiosensitizers become metabolically bound preferentially to hypoxic cells and at least 10/sup 9/ adducts/cell can be tolerated as non-toxic. EMT-6 tumor cells have been incubated in hypoxia in the presence of /sup 3/H-Misonidazole and /sup 125/I-Azomycin Riboside for various times and the amount of /sup 3/H or /sup 125/I bound/cell was determined. Cells were stored as monolayers at 25"0C for up to 96 hr to accumulate radioactive decays and transferred at various times to 37"0C for colony-forming assays. No radiation inactivation was measured in cells which had incorporated at least 10/sup 6/ /sup 3/H or 10/sup 5/ /sup 125/I atoms. Previous studies had shown that -- 1% of MISO adducts to EMT-6 cells was associated with cellular DNA. These data indicate that the radiation-induced damage produced by these quantities of bound /sup 3/H or /sup 125/I causes little or not cell inactivation. The ...

19

Reversible Inactivation of Nitrate Reductase by NADH and the Occurrence of Partially Inactive Enzyme in the Wheat Leaf 1  

UK PubMed Central (United Kingdom)

Nitrate reductase from wheat (Triticum aestivum L. cv Bindawarra) leaves is inactivated by pretreatment with NADH, in the absence of nitrate, a 50% loss of activity occurring in 30...Full Text Available

1983-03-01

20

Phenothiazine-N-carbonyl chloride, a specific inactivator of chymotrypsin  

UK PubMed Central (United Kingdom)

Phenothiazine-N-carbonyl chloride inactivated chymotrypsin and trypsin by means of a 1:1 stoicheiometric reaction. Its reaction with chymotrypsin was 29 times as fast as that with...Full Text Available

1970-07-01

21

Inactivation of Ascaris Eggs in Source-Separated Urine and Feces by Ammonia at Ambient Temperatures?  

UK PubMed Central (United Kingdom)

Sustainable management of toilet waste must prevent disease transmission but allow reuse of plant nutrients. Inactivation of uterus-derived Ascaris suum eggs was studied in relation...Full Text Available

2009-02-01

22

Inactivation and Heat Stabilization of Poliovirus by 2-Thiouracil 1  

UK PubMed Central (United Kingdom)

Treatment of poliovirus Type I with 10−3m 2-thiouracil (2-TU) resulted in the inactivation of greater than 90% of the virus infectivity and stabilization of approximately...Full Text Available

1967-08-01

23

Immunization of foxes by the intestinal route using an inactivated rabies vaccine.  

UK PubMed Central (United Kingdom)

Approximately 30% of foxes given two doses of an inactivated rabies antigen delivered directly into the intestinal tract developed an immune response as measured by rabies serum neutralizing antibodies....Full Text Available

1989-01-01

24

Review of Vaccinia Virus and Baculovirus Viability Versus ...  

Science.gov (United States)

... hazards. One study targeted the effects of common household disinfectants on virus inactivation (Butcher and Ulaeto, 2005). ...

2008-03-01

25

Depuration of shellfish by irradiation: Final technical report, October 1, 1987--March 31, 1989  

International Nuclear Information System (INIS)

Studies by the University of Lowell Radiation Laboratory and the US National Marine Fisheries Service N.E. Laboratory in Gloucester, MA on softshelled clams (Mya arenaria) demonstrated the effectiveness of low to medium doses of Cobalt 60 source gamma irradiation in the inactivation of Escherichia coli, Salmonella typhimurium, Staphylococcus aureus and Streptococcus faecalis. Post-irradiation survival and organoleptic studies when extended to hardshelled clams (Mercinaria mercenaria) and American oysters (Crassostrea virginica) showed no significant decline in consumer qualities or 6 day post irradiation survival in oysters at doses of up to 3.0 kGy. The capacities of the American oyster to sustain relatively high doses of gamma irradiation were demonstrated by 6 day post-exposure survivorship values of greater than 90% for samples receiving 3.0, 5.0 and 7.0 kGy. Initial studies of inactivation of Polio I virus and a simian ...

26

Inactivation of Microcystis aeruginosa with Contact Glow Discharge Electrolysis  

British Library Electronic Table of Contents (United Kingdom)

This work investigated the inactivation of Microcystis aeruginosa (MA) with contact glow discharge electrolysis (CGDE). The influences of applied voltage, current and treatment time on the inactivation rate were critically examined. Based on the above results, the optimal conditions were chosen to sufficiently utilize chemically active species and enhance the inactivation of MA. Under the optimal conditions (voltage: 530?V; current: 30?mA; treatment time: 20?min), the inactivation rate of algae was more than 90% within 5?days incubation after inoculating. At the same time, the concentrations of Chlorophyll-a and dehydrogenase decreased, which demonstrated that 20?min CGDE treatment could effectively inhibit the growth of MA and caused deterioration of cell integrity. The present work would...

2011-01-01

27

Shellfish depuration by gamma irradiation: Final report for the period October 1, 1985-September 30, 1986  

International Nuclear Information System (INIS)

Irradiation of live bivalve molluscs is a promising new technique to reduce the public health threats of viral and bacterial pathogens in the consumption of raw shellfish. In studies conducted within the past year, live hardshelled clams and oysters were innoculated with Simian Rotavirus SA-11, Poliovirus I, and Hepatitis-A virus and treated with gamma ray ionizing radiation from University of Lowell/DOE 800,000 Curie "6"0Co source over a dose range of 0.5--10 kiloGray (50--1000 kilorad) to determine the effectiveness of the process in eliminating viral activity and thus easing the potential viral health threats associated with uncooked bivalves. Two viral strains, SA-11 and Poliovirus I, were employed as models to perfect laboratory technique and to estimate the most appropriate range of dose exposures necessary for optimal inactivation of the infectious pathogen, Hepatitis A. Post-irradiation survivorship of the oysters and quahogs was ...

28

Application of the microbiological method DEFT/APC to detect minimally processed vegetables treated with gamma radiation  

Energy Technology Data Exchange (ETDEWEB)

Marketing of minimally processed vegetables (MPV) are gaining impetus due to its convenience, freshness and apparent health effect. However, minimal processing does not reduce pathogenic microorganisms to safe levels. Food irradiation is used to extend the shelf life and to inactivate food-borne pathogens. In combination with minimal processing it could improve safety and quality of MPV. A microbiological screening method based on the use of direct epifluorescent filter technique (DEFT) and aerobic plate count (APC) has been established for the detection of irradiated foodstuffs. The aim of this study was to evaluate the applicability of this technique in detecting MPV irradiation. Samples from retail markets were irradiated with 0.5 and 1.0 kGy using a {sup 60}Co facility. In general, with a dose increment, DEFT counts remained similar independent of the irradiation while APC counts decreased gradually. The difference of the two counts gradually increased with ...

2009-07-15

29

Nonphotochemical Hole-Burning Imaging Studies of in vitro Carcinoma and Normal Cells Utilizing a Mitochondrial Specific Dye  

Energy Technology Data Exchange (ETDEWEB)

Low temperature Nonphotochemical Hole Burning (NPHB) Spectroscopy of the dye rhodamine 800 (MF680) was applied for the purpose of discerning differences between cultured normal and carcinoma ovarian surface epithelial (OSE) cells. Both the cell lines were developed and characterized at the Mayo Clinic (Rochester, MN), with the normal cell line having been transfected with a strain of temperature sensitive Simian Virus 40 Large T Antigen (SV40) for the purpose of extending the life of the cell culture without inducing permanent changes in the characteristics of the cell line. The cationic lipophilic fluorophore rhodamine 800 preferentially locates in in situ mitochondria due to the high lipid composition of mitochondria and the generation of a large negative membrane potential (relative to the cellular cytoplasm) for oxidative phosphorylation. Results presented for NPHB of MF680 located in the cells show significant differences between the two ...

2002-06-27

30

Nonphotochemical Hole-Burning Imaging Studies of In Vitro Carcinoma and Normal Cells Utilizing a Mitochondrial Specific Dye  

Energy Technology Data Exchange (ETDEWEB)

Low temperature Nonphotochemical Hole Burning (NPHB) Spectroscopy of the dye rhodamine 800 (MF680) was applied for the purpose of discerning differences between cultured normal and carcinoma ovarian surface epithelial (OSE) cells. Both the cell lines were developed and characterized at the Mayo Clinic (Rochester, MN), with the normal cell line having been transfected with a strain of temperature sensitive Simian Virus 40 Large T Antigen (SV40) for the purpose of extending the life of the cell culture without inducing permanent changes in the characteristics of the cell line. The cationic lipophilic fluorophore rhodamine 800 preferentially locates in in situ mitochondria due to the high lipid composition of mitochondria and the generation of a large negative membrane potential (relative to the cellular cytoplasm) for oxidative phosphorylation. Results presented for NPHB of MF680 located in the cells show significant differences between the two ...

2002-08-01

31

Thermoactivation of viruses by microwaves  

Energy Technology Data Exchange (ETDEWEB)

Eight different viruses, suspended in drinking water, were examined for their ability to be inactivated by microwaves from a microwave oven. Up to a virus content of 10/sup 5/ TCID/sub 50//ml inactivation was successful within a few minutes of microwave treatment and occurred in parallel to the heat stability of the viruses. Evidence for direct effects of microwaves on viruses could not be detected. 7 of the viruses studied were inactivated rapidly when temperatures of 50 to 65/sup 0/C under microwave treatment were reached in the flowing water, while a bovine parvovirus was only inactivated by temperatures above 90/sup 0/C. The advantages of a thermal virus-decontamination of fluids and material by microwaves are discussed.

1981-01-01

32

Molecular Genetics and Carcinogenesis Section  

Science.gov (United States)

The Molecular Genetics and Carcinogenesis Section conducts studies using human epithelial cells to assess: activation of proto-oncogenes by chemical and physical carcinogens; inactivation and dysregulation of tumor suppressor genes by chemical and physical

33

Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB  

UK PubMed Central (United Kingdom)

Activating AMPK or inactivating calcineurin slows ageing in Caenorhabditis elegans1,2...Full Text Available

2011-02-17

34

Radial distribution of dose and cross-sections for the inactivation of dry enzymes and viruses  

International Nuclear Information System (INIS)

A new semi-empirical algorithm for the radial distribution of dose is compared with available data. The algorithm is used to calculate the inactivation cross section for dry enzymes and viruses using an extended target model of a 1-hit detector. Agreement with data is at about the 15% level, approximating the precision of the data itself. (author).

1985-05-01

35

Efficacy of a heat inactivated hepatitis B vaccine in male homosexuals: outcome of a placebo controlled double blind trial.  

UK PubMed Central (United Kingdom)

The efficacy of a heat inactivated hepatitis B virus vaccine, containing 3 micrograms hepatitis B surface antigen (HBsAg), was studied in a high risk group of 800 susceptible homosexual men by a randomised...Full Text Available

1983-04-23

36

Covalent Modification of Thr302 in Cytochrome P450 2B1 by the Mechanism-Based Inactivator 4-tert-Butylphenylacetylene  

UK PubMed Central (United Kingdom)

The mechanism of inactivation of cytochrome P450 2B1 (CYP2B1) by 4-tert-butylphenylacetylene (BPA) has been characterized previously to be caused by the covalent binding of a reactive...Full Text Available

2010-06-01

37

Contraction-mediated inactivation of glycogen synthase is accompanied by inactivation of glycogen synthase phosphatase in human skeletal muscle.  

UK PubMed Central (United Kingdom)

Activities of glycogen synthase (GS) and GS phosphatase were determined on human muscle biopsies before and after isometric contraction at 2/3 maximal voluntary force. Total GS activity did not change...Full Text Available

1989-05-01

38

Novel approach to decontaminate food-packaging from pathogens in non-thermal and not chemical way: Chlorophyllin-based photosensitization  

British Library Electronic Table of Contents (United Kingdom)

This study was focused on the possibility to inactivate main food pathogens, their spores and biofilms on the surface of packaging material polyolefine by Na-chlorophyllin (Na-Chl)-based photosensitization and to compare efficiency of this treatment with conventional antimicrobials. Data indicate that Bacillus cereus and Listeria monocytogenes were effectively inactivated (7 log) by Na-Chl (7.5x10-7M)-based photosensitization in vitro and on the surface of packaging. Meanwhile to achieve adequate inactivation of thermo-resistant strains, spores or biofilms the higher Na-Chl concentration and longer illumination times had to be used. Comparison of different surface decontamination treatments reveal that photosensitization is much more effective against B. cereus and L. monocytogenes attache...

2011-01-01

39

Inactivation of several strains of Listeria monocytogenes attached to the surface of packaging material by Na-Chlorophyllin-based photosensitization  

British Library Electronic Table of Contents (United Kingdom)

This study was focused on the possibility to inactivate thermosensitive Listeria monocytogenes ATCL3C 7644 and thermoresistant 56 Ly strain by Na-Chlorophyllin (Na-Chl)-based photosensitization in vitro and on the surface of packaging. Comparative analysis of antimicrobial efficiency of photosensitization with conventional surface cleaning was performed. Data indicate that both Listeria strains, after incubation with Na-Chl and following illumination (l=400nm, 20mWcm-2), were inactivated by 7 log in vitro. This treatment cleaned both Listeria strains from packaging surfaces. Comparative analysis indicates that washing with water diminishes pathogens by less than 1 log, 200ppm Na-hypochlorite by 1.7 log, Na-Chl-based photosensitization by 4.5 log. Listeria biofilms were totally removed from...

2010-01-01

40

Relationship of DNA repair processes to mutagenesis and carcinogenesis in mammalian cells. Progress report, November 1, 1979-October 31, 1980  

International Nuclear Information System (INIS)

The objective of this research is to determine the role of DNA repair in mutagenesis and carcinogenesis in mammalian cells. Use of the host-cell reactivation viral suicide enrichment procedure was initiated in the isolation of repair-deficient mutants. Lightly mutagenized BHK cells were infected with irradiated Herpes simplex virus (HSV); several radiation-sensitive strains were isolated among the survivors of the infection. The characterization of these strains is progressing and the enrichments are continuing. That alterations in the frequency of mutation of C3H/10T 1/2 cells, occurring as a result of holding the cells in a confluent state following treatment with ethylmethane sulfonate, parallel the alterations in the frequency of neoplastic transformation was found. The repair capabilities of BHK cells were found to be intermediate in comparison to repair-proficient and -deficient human cells with regard to the reactivation of HSV treated with various ...

41

Vibrio cholerae Hemagglutinin/Protease Inactivates CTX?  

UK PubMed Central (United Kingdom)

Pathogenic strains of Vibrio cholerae are lysogens of the filamentous phage CTXφ, which carries the genes for cholera toxin (ctxAB). We found that the titers...Full Text Available

1998-09-01

42

Type I Collagen Is a Genetic Modifier of Matrix Metalloproteinase 2 in Murine Skeletal Development  

UK PubMed Central (United Kingdom)

Recessive inactivating mutations in human matrix metalloproteinase 2 (MMP2, gelatinase A) are associated with syndromes that include abnormal facial appearance, short stature, and severe bone...Full Text Available

2007-06-01

43

Staphylococcus aureus Aconitase Inactivation Unexpectedly Inhibits Post-Exponential-Phase Growth and Enhances Stationary-Phase Survival  

UK PubMed Central (United Kingdom)

Staphylococcus aureus preferentially catabolizes glucose, generating pyruvate, which is subsequently oxidized to acetate under aerobic growth conditions. Catabolite repression of the...Full Text Available

2002-11-01

44

Poliomyelitis control in Israel, the West Bank and Gaza Strip: changing strategies with the goal of eradication in an endemic area.  

UK PubMed Central (United Kingdom)

Israel has faced the challenge presented by epidemic poliomyelitis by using different immunization strategies. In the 1950s, inactivated poliovirus vaccine (IPV) helped to reduce the total burden of...Full Text Available

1994-01-01

45

Neutral endopeptidase inhibits prostate cancer cell migration by blocking focal adhesion kinase signaling  

UK PubMed Central (United Kingdom)

Neutral endopeptidase 24.11 (NEP, CD10) is a cell-surface enzyme expressed by prostatic epithelial cells that cleaves and inactivates neuropeptides implicated in the growth of androgen-independent prostate...Full Text Available

2000-12-01

46

Inoculation of Scytalidium thermophilum in Button Mushroom Compost and Its Effect on Yield  

UK PubMed Central (United Kingdom)

Scytalidium thermophilum isolates in culture, as well as the endogenous strain(s) in mushroom compost, were inactivated at 70°C. This temperature was used to pasteurize composts...Full Text Available

1994-09-01

47

Inactivating cholecystokinin-2 receptor inhibits progastrin-dependent colonic crypt fission, proliferation, and colorectal cancer in mice  

UK PubMed Central (United Kingdom)

Hyperproliferation of the colonic epithelium, leading to expansion of colonic crypt progenitors, is a recognized risk factor for colorectal cancer. Overexpression of progastrin, a nonamidated and incompletely...Full Text Available

2009-09-01

48

Identification of the Haemophilus influenzae tolC Gene by Susceptibility Profiles of Insertionally Inactivated Efflux Pump Mutants  

UK PubMed Central (United Kingdom)

Isogenic strains containing insertional disruptions of 10 Haemophilus influenzae Rd genes were investigated for their effects on the susceptibility of the organism to various classes...Full Text Available

2004-04-01

49

Hepatocyte entry leads to degradation of autoreactive CD8 T cells  

UK PubMed Central (United Kingdom)

Although most self-reactive T cells are eliminated in the thymus, mechanisms to inactivate or control T cells specific for extrathymic antigens are required and exist in the periphery. By investigating...Full Text Available

2011-10-04

50

Functional Interactions between Retinoblastoma and c-MYC in a Mouse Model of Hepatocellular Carcinoma  

UK PubMed Central (United Kingdom)

Inactivation of the RB tumor suppressor and activation of the MYC family of oncogenes are frequent events in a large spectrum of human cancers. Loss of RB function and MYC activation are thought to...Full Text Available

51

Enhanced biosorptive removal of cadmium from aqueous solutions by silicon dioxide nano-powder, heat inactivated and immobilized Aspergillus ustus  

British Library Electronic Table of Contents (United Kingdom)

Heat inactivated Aspergillus ustus (Asp), silicon dioxide-nano-powder (N Si), and silicon dioxide nano-powder-combined-heat inactivated Aspergillus ustus (N Si Asp) were used to study the biosorption of Cd(II) from aqueous solutions via batch equilibrium technique. Surface characterization and immobilization of the fungal cells on silicon dioxide-nano-powder were examined and confirmed by using FT-IR and ESM analysis. Cadmium biosorption processes were investigated under the effect of pH, contact time, sorbent dosage and initial metal concentration. The three examined sorbents were found to exhibit maximum mmolg^-^1 capacity values in pH 7.0. The maximum determined cadmium capacity by silicon dioxide-nano-powder (N Si) (600mmolg^-^1) was found higher than that exhibited by the heat inactiv...

2011-01-01

52

Emulsified Nanoparticles Containing Inactivated Influenza Virus and CpG Oligodeoxynucleotides Critically Influences the Host Immune Responses in Mice  

UK PubMed Central (United Kingdom)

BackgroundAntigen sparing and cross-protective immunity are regarded as crucial in pandemic influenza vaccine development. Both targets can be achieved by adjuvantation strategy...Full Text Available

53

E2f binding-deficient Rb1 protein suppresses prostate tumor progression in vivo  

UK PubMed Central (United Kingdom)

Mutational inactivation of the RB1 tumor suppressor gene initiates retinoblastoma and other human cancers. RB1 protein (pRb) restrains cell proliferation by binding...Full Text Available

2011-01-11

54

Delineating Bacteriostatic and Bactericidal Targets in Mycobacteria Using IPTG Inducible Antisense Expression  

UK PubMed Central (United Kingdom)

In order to identify novel high value antibacterial targets it is desirable to delineate whether the inactivation of the target enzyme will lead to bacterial death or stasis. This knowledge is particularly...Full Text Available

55

Cyst Formation in Kidney via B-Raf Signaling in the PKD2 Transgenic Mice*  

UK PubMed Central (United Kingdom)

The pathogenic mechanisms of human autosomal dominant polycystic kidney disease (ADPKD) have been well known to include the mutational inactivation of PKD2. Although haploinsufficiency...Full Text Available

2009-03-13

56

Complement Evasion by Borrelia burgdorferi: Serum-Resistant Strains Promote C3b Inactivation  

UK PubMed Central (United Kingdom)

The most characteristic features of the Lyme disease pathogens, the Borrelia burgdorferi sensu lato (s.l.) group, are their ability to invade tissues and to circumvent the immune defenses...Full Text Available

2001-06-01

57

Clinical outcomes and management of mechanism-based inhibition of cytochrome P450 3A4  

UK PubMed Central (United Kingdom)

Mechanism-based inhibition of cytochrome P450 (CYP) 3A4 is characterized by NADPH-, time-, and concentration-dependent enzyme inactivation, occurring when some drugs are converted by CYPs to reactive...Full Text Available

2005-03-01

58

A novel Na+ channel splice form contributes to the regulation of an androgen-dependent social signal  

UK PubMed Central (United Kingdom)

Na+ channels are often spliced but little is known about the functional consequences of splicing. We have been studying the regulation of Na+ current inactivation in an...Full Text Available

2008-09-10

59

A cytosine methyltransferase homologue is essential for repeat-induced point mutation in Neurospora crassa  

UK PubMed Central (United Kingdom)

During sexual development, Neurospora crassa inactivates genes in duplicated DNA segments by a hypermutation process, repeat-induced point mutation (RIP). RIP introduces C:G to T:A...Full Text Available

2002-06-25

60

A Response Regulator That Represses Transcription of Several Virulence Operons in the Group A Streptococcus  

UK PubMed Central (United Kingdom)

A search for homologs of the Bacillus subtilis PhoP response regulator in the group A streptococcus (GAS) genome revealed three good candidates. Inactivation of one of these, recently...Full Text Available

1999-06-01

61

Effective use of optimized, high-dose (50 kGy) gamma irradiation for pathogen inactivation of human bone allografts.  

Science.gov (United States)

The safety of tissue allografts has come under increased scrutiny due to recent reports of allograft-associated bacterial and viral infections in tissue recipients. We report that 50 kGy of gamma irradiation, nearly three times the dose currently used, is an effective pathogen inactivation method when used under optimized conditions that minimize damage to the tissue. Cancellous bone dowels treated with a radioprotectant solution and 50 kGy of optimized irradiation had an ultimate compressive strength and modulus of elasticity equal to conventionally irradiated (18 kGy) and non-irradiated control bone grafts. We subjected bone dowels treated with this pathogen inactivation method to an in vitro cytotoxicity test using three different mammalian cell lines and concluded that the treated grafts were not cytotoxic. The log reduction of nine pathogens spiked into radioprotectant-treated bone irradiated to 50 kGy was also tested. We achieved 4.9 logs ...

2005-05-01

62

Dendroaspis natriuretic peptide and the designer natriuretic peptide, CD-NP, are resistant to proteolytic inactivation.  

Science.gov (United States)

Designer natriuretic peptides (NPs) represent an active area of drug development. In canine and human studies, the designer natriuretic peptide CD-NP demonstrated more desirable therapeutic potential than recombinant B-type NP (BNP), which is known as nesiritide and is approved for treatment of acute decompensated heart failure. However, why CD-NP is more effective than BNP is not known. We previously reported that CD-NP is a poorer activator of human guanylyl cyclase-A (GC-A) and a better activator of human guanylyl cyclase-B than BNP. Here, guanylyl cyclase bioassays were used to compare the susceptibility of CD-NP verses ANP, BNP, CNP and DNP to inactivation by human kidney membranes. The half time (t(1/2)) for CD-NP inactivation was increased by factors of 13, 3 and 4 compared to ANP, BNP and CNP, respectively, when measured in the same assay. Surprisingly, DNP failed to undergo complete inactivation and was the most ...

2011-04-01

63

Formation of an intramolecular cystine disulfide during the reaction of 8-azidoguanosine 5'-triphosphate with cytosolic phosphoenolpyruvate carboxykinase (GTP) causes inactivation without photolabeling  

International Nuclear Information System (INIS)

Phosphoenolpyruvate carboxykinase (GTP) (PEPCK) specifically utilizes a guanosine or inosine nucleotide as a substrate, yet it does not share extended sequence homology with other GTP-binding proteins, and the molecular basis for its nucleotide specificity is not understood. In an effort to locate the enzyme's nucleotide-binding site, the authors have studied the interaction of cytosolic PEPCK from rat liver with the photoprobe 8-azidoGTP, which fulfills the criteria of a specific photoaffinity label for PEPCK. The photoprobe binds reversibly to the enzyme prior to modification and at low concentrations causes greater than 60% inactivation-GTP provides nearly complete protection against inactivation by 8-azidoGTP, whereas phosphoenolpyruvate and metal ions provide partial protection. In addition, the photoprobe is a substrate for the enzyme and has a K_m similar to that for GTP. However, the extent of covalent modification by ["3"2P]8-azido-GTP ...

64

Formation of an intramolecular cystine disulfide during the reaction of 8-azidoguanosine 5 prime -triphosphate with cytosolic phosphoenolpyruvate carboxykinase (GTP) causes inactivation without photolabeling  

Energy Technology Data Exchange (ETDEWEB)

Phosphoenolpyruvate carboxykinase (GTP) (PEPCK) specifically utilizes a guanosine or inosine nucleotide as a substrate, yet it does not share extended sequence homology with other GTP-binding proteins, and the molecular basis for its nucleotide specificity is not understood. In an effort to locate the enzyme's nucleotide-binding site, the authors have studied the interaction of cytosolic PEPCK from rat liver with the photoprobe 8-azidoGTP, which fulfills the criteria of a specific photoaffinity label for PEPCK. The photoprobe binds reversibly to the enzyme prior to modification and at low concentrations causes greater than 60% inactivation-GTP provides nearly complete protection against inactivation by 8-azidoGTP, whereas phosphoenolpyruvate and metal ions provide partial protection. In addition, the photoprobe is a substrate for the enzyme and has a K{sub m} similar to that for GTP. However, the extent of covalent modification by ...

1989-11-28

65

Measurements of bragg curve for 75 MeV/u "1"2C ion beam and its inactivation effect on melanoma cells  

International Nuclear Information System (INIS)

Relative doses of 75 MeV/u "1"2C ion beam after passing through different thickness of degraders were measured with the double ionization chamber method. The degrader's thickness equalized to penetration depth of the beam in water and its Bragg curve were obtained. The measured Bragg curve is compared with that calculated based on a model set up by the authors. Meanwhile, the inactivation effect of the ion beam passing through different thickness of degraders on melanoma (B_1_6) cells was measured, and the corresponding survival fraction data for B_1_6 cells were acquired

1998-08-01

66

Mary Lyon and the hypothesis of random X chromosome inactivation  

British Library Electronic Table of Contents (United Kingdom)

The 50th anniversary of Mary Lyon?s 1961 Nature paper, proposing random inactivation in early embryonic life of one of the two X chromosomes in the cells of mammalian females, provides an opportunity to remember and celebrate the work of those involved. While the hypothesis was initially put forward by Lyon based on findings in the mouse, it was founded on earlier studies, notably the work of Susumu Ohno; it was also suggested independently by Beutler and colleagues using experimental evidence from a human X-linked disorder, glucose-6-phosphate dehydrogenase deficiency, and has proved to be of as great importance for human and medical genetics as it has for general mammalian genetics. Alongside the hypothesis itself, previous cytological studies of mouse and human chromosomes, and the obse...

2011-01-01

67

Quality engineering and control. Annual progress report, January-December 1981  

International Nuclear Information System (INIS)

Brief summaries are given of research carried out in the following areas: absorption spectroscopy of titanium, niobium, and molybdenum in uranium alloys; atomic absorption spectroscopy of selenium in stainless steel, computer program improvements for spectrophotometer control, and detection of beryllium in stack gases; electrolysis for inactivation of bacteria in cooling-tower water; improved solvent analysis by gas chromatography; sequential radionuclide separation for various sample matrices; progress on an electron microprobe analyzer; and miscellaneous projects.

68

Kes1p shares homology with human oxysterol binding protein and participates in a novel regulatory pathway for yeast Golgi-derived transport vesicle biogenesis.  

UK PubMed Central (United Kingdom)

The yeast phosphatidylinositol transfer protein (Sec14p) is required for biogenesis of Golgi-derived transport vesicles and cell viability, and this essential Sec14p requirement is abrogated by inactivation...Full Text Available

1996-12-02

69

Interdependent Roles for Accessory KChIP2, KChIP3 and KChIP4 Subunits in the Generation of Kv4-encoded IA Channels in Cortical Pyramidal Neurons  

UK PubMed Central (United Kingdom)

The rapidly activating and inactivating voltage-dependent outward K+ (Kv) current, IA, is widely expressed in central and peripheral neurons. IA has long been...Full Text Available

2010-10-13

70

IL-6 promotes nonthyroidal illness syndrome by blocking thyroxine activation while promoting thyroid hormone inactivation in human cells  

UK PubMed Central (United Kingdom)

Nonthyroidal illness syndrome (NTIS) is a state of low serum 3,5,3′ triiodothyronine (T3) that occurs in chronically ill patients; the degree of reduction in T3 is associated...Full Text Available

2011-05-02

71

Effects of gamma irradiation on microbial contamination and extraction yields of Korean medicinal herbs  

Energy Technology Data Exchange (ETDEWEB)

Effects of gamma irradiation on hygienic quality and extraction yields in twenty-one kinds of Korean medicinal herbs were investigated. Gamma irradiation at 5-10 kGy inactivated contaminating microorganisms. The total extraction yield in fifteen kinds of the investigated medicinal herbs increased by 5-25% by a dose of 10 kGy. (author)

2000-01-01

72

Canonical and Alternative Pathways in Cyclin-Dependent Kinase 1/Cyclin B Inactivation upon M-Phase Exit in Xenopus laevis Cell-Free Extracts  

UK PubMed Central (United Kingdom)

Cyclin-Dependent Kinase 1 (CDK1) is the major M-phase kinase known also as the M-phase Promoting Factor or MPF. Studies performed during the last decade have shown many details of how CDK1 is regulated...Full Text Available

73

A Small-Molecule p53 Activator Induces Apoptosis through Inhibiting MDMX Expression in Breast Cancer Cells12  

UK PubMed Central (United Kingdom)

The tumor suppressor p53 is often inactivated in breast cancer cells because the overexpression of its repressors (e.g., MDM2 and MDMX). Restoration of p53 activity by small molecules through counteracting...Full Text Available

2011-07-01

74

A New Metal-Binding Site for Yeast Phosphoglycerate Kinase as Determined by the Use of a Metal-ATP Analog  

UK PubMed Central (United Kingdom)

Suicide substrate β, γ-bidentate Rh(III)ATP (RhATP) was used to map the metal ion-binding site in yeast phosphoglycerate kinase (PGK). Cleavage of the RhATP-inactivated enzyme with...Full Text Available

1997-02-01

75

Some comments on BEIR III  

International Nuclear Information System (INIS)

... organizations irradiation radiation doses radiation effects RADIATIONS.

1982-01-01

76

Radiation technology of wood-plastic composite materials  

International Nuclear Information System (INIS)

... radiation effects RADIATIONS. WOOD-PLASTIC COMPOSITES.

1981-10-02

77
78

Mechanism of adenylate kinase. Dose adenosine 5'-triphosphate bind to the adenosine 5'-monophosphate site  

Energy Technology Data Exchange (ETDEWEB)

Although the subtrate binding properties of adenylate kinase (AK) have been studied extensively by various biochemical and biophysical techniques, it remains controversial whether uncomplexed adenosine 5'-triphosphate (ATP) binds to the adenosine 5'-monophosphate (AMP) site of AK. The authors present two sets of experiments which argue against binding of ATP to the AMP site. (a) /sup 31/P nuclear magnetic resonance titration of ATP with AK indicated a 1:1 stoichiometry on the basis of changes in coupling constants and line widths. This ruled out binding of ATP to both sites. (b) ATP and MgATP were found to behave similarly by protecting AK from spontaneous inactivation while AMP showed only a small degree of protection. Such inactivation could also be protected or reversed by dithioerythritol and is most likely due to oxidation of sulfhydryl groups, one of which (cysteine-25) is located near the MgATP site. The results support ...

1987-10-06

79

Influence of anaerobic microbial activity on biosorption of 2,4-dichlorophenol  

Energy Technology Data Exchange (ETDEWEB)

Biosorption is an important removal mechanism in treating hydrophobic toxic organics in biological reactors. Equilibrium sorption isotherms and sorption kinetics of 2,4-dichlorophenol on live and chemically inactive anaerobic granules were studied. A metabolic inhibitor was used to inactivate the biological activity of the biomass. Results showed that the difference in the biosorption of live and chemically inactive anaerobic granules is not significant. This would suggest that anaerobic biosorption is mainly a physical-chemical process and that metabolic-mediated diffusion in the process is negligible. 12 refs., 3 tabs., 7 figs.

1995-12-31

80

Therapeutic efficacy of intralesional 131I-labelled hyaluronectin in grafted human glioblastoma  

Energy Technology Data Exchange (ETDEWEB)

The grafted human glioblastoma cell CB109 was used as a model for intralesional therapy with 131I-labelled hyaluronectin glycoprotein (131I-HN). 131I-HN bound specifically to in situ hyaluronic acid (HA), a main component of the extracellular matrix which is involved in tumour invasion. Labelling experimental conditions were determined and, finally, 25 {mu}Ci/{mu}gHN, 1 {mu}g chloramine-T/{mu}gHN and a 60-s stirring period provided a 131I-HN preparation with an optimal affinity for HA (64% compared to unlabelled HN). Following intratumoral injection, 131I-HN was retained with a limited diffusion outside the tumour. On day 4 the radioactivity concentrated in the tumour was still 25 times greater than that in the liver, spleen and kidneys combined. For therapeutic assays, 65 {mu}Ci 131I-HN was injected into the tumour, resulting in a delivery of 6.8 Gy over a 7-day period. Controls received unlabelled HN, heat-inactivated HN, a mixture of ...

2000-07-01

81

Inactivating calcium-sensing receptor mutations in patients with primary hyperparathyroidism.  

Science.gov (United States)

Objective:? Primary hyperparathyroidism (HPT) is characterised by autonomous secretion of PTH from enlarged parathyroid glands leading, in most patients, to asymptomatic hypercalcaemia. Familial hypocalciuric hypercalcaemia (FHH) is an autosomal dominant disorder caused by inactivating mutations in the calcium sensing receptor (CaSR) gene; it is characterised by lifelong and usually asymptomatic hypercalcaemia. Establishing the correct diagnosis is important because surgery can be curative in HPT, but ineffective in FHH. There is overlap in the diagnostic criteria for the two disorders and some patients carrying inactivating mutations in the CaSR gene, which is suggestive of FHH, also have HPT with hyperplastic parathyroid glands or adenomas. Design and Patients:? CaSR gene mutations were analyzed and clinical and biochemical parameters evaluated in 139 consecutive out-patients presenting with hypercalcaemia and suspected of having HPT. ...

2011-03-29

82

Cysteinyl peptides of rabbit muscle pyruvate kinase labeled by the affinity label 8-((4-bromo-2,3-dioxobutyl)thio)adenosine 5 prime -triphosphate  

Energy Technology Data Exchange (ETDEWEB)

The affinity label 8-((4-bromo-2,3-dioxobutyl)thio)adenosine 5{prime}-triphosphate (8-BDB-TA-5{prime}-TP) reacts covalently with rabbit muscle pyruvate kinase, incorporating 2 mol of reagent/mol of enzyme subunit upon complete inactivation. Protection against inactivation is provided by phosphoenolpyruvate, K{sup +}, and Mn{sup 2+} and only 1 mol of reagent/mol of subunit is incorporated. The authors have now identified the resultant modified residues. After reaction with 8-BDB-TA-5{prime}-TP at pH 7.0, modified enzyme was incubated with ({sup 3}H)NaBH{sub 4} to reduce the carbonyl groups of enzyme-bound 8-BDB-TA-5{prime}-TP and to introduce a radioactive tracer into the modified residues. Following carboxymethylation and digestion with trypsin, the radioactive peptides were separated on a phenylboronate agarose column followed by reverse-phase high-performance liquid chromatography in 0.1% trifluoroacetic acid with an acetonitrile gradient. ...

1990-03-13

83

The Use of Medical Images in Planning and Delivery of Radiation Therapy  

UK PubMed Central (United Kingdom)

Abstract The authors provide a survey of how images are used in radiation therapy to improve the precision of radiation therapy plans, and delivery of radiation treatment. In contrast...Full Text Available

1997-09-01

85
86

Animal Models for Radiation Injury, Protection and Therapy  

Science.gov (United States)

... radiation during clinical therapy and exposures due to radiation accidents or attacks, in which the doses are uncontrolled ... only be used off-label in victims of radiation accidents or attacks. The idea...

87

Statistical cut-off criterion  

International Nuclear Information System (INIS)

... radiation effects human populations low dose irradiation neoplasms radiation

1980-01-01

88

Radiation protection and the management of radioactive waste in the oil and gas industry  

CERN Document Server

Radiation protection and the management of radioactive waste in the oil and gas industry

2003-01-01

90

Higher harmonics of spontaneous radiation of ultrarelativistic channeled particles  

International Nuclear Information System (INIS)

The case of spontaneous radiation of channeled ultrarelativistic particles is considered when the dipolarity condition is not satisfied. The change of the particle longitudinal velocity affecting the maximum radiation frequency is included. The angular and frequency characteristics of the radiation for superhigh energies are studied for the first time. It is shown that there is an optimum energy at which the radiation density is maximum. The influence of the angle at which electrons enter a crystal and of the beam divergence on the radiation is investigated. The problem of quasichanneled particle radiation and also the radiation in axis-plane transitions are considered. (author).

1980-06-01

92

Contribution to the radiation preparation of wood-plastic materials. Pt. 7  

International Nuclear Information System (INIS)

... odd nuclei organic compounds radiation effects radioisotopes synthesis

1974-01-01

93

Contribution to the radiation preparation of wood-plastic materials. Pt. 6  

International Nuclear Information System (INIS)

... compounds polymers polyolefins polyvinyls radiation effects SYNTHESIS.

1974-01-01

94

Contribution to the radiation preparation of wood-plastic materials Pt. 3  

International Nuclear Information System (INIS)

... compounds plants radiation effects radioisotopes reaction kinetics trees

1974-01-01

95

Compact Proton and Carbon Ion Synchrotrons for Radiation Therapy  

CERN Document Server

Compact Proton and Carbon Ion Synchrotrons for Radiation Therapy

2002-01-01

96

? j -  

Science.gov (United States)

duced and spontaneous radiation. The amount of polarization is ... of the induced and spontaneous radiation patterns. Therefore ...

97

Systematics of average radiative width of heavy nuclides  

Energy Technology Data Exchange (ETDEWEB)

Systematics of neutron capture radiative width were studied in the target element range from Th to Cm. Reduced radiative widths were analyzed with a simple radiative width formula based on E1 transition. Average radiative width is presented with the standard deviation of 15%. (author)

1999-03-01

98

Development of internal dose estimation software on radiation protection  

International Nuclear Information System (INIS)

Objective: To develop a computerized method of internal dose estimation on radiation protection. Methods: Based on MIRD mathematic model of the organs and by means of the programming language of MS Visual Basic 6.0, a computer program of dose estimation in internal radiation was developed for radiation protection. Results: The computerized method of dose estimation for internal radiation was completed. Conclusions: This computerized method is very convenient for internal radiation dose estimation of several aspects. It can also be used in radiation accident. (authors)

2008-10-01

99

The hippo pathway in biological control and cancer development  

British Library Electronic Table of Contents (United Kingdom)

Abstract The Hippo pathway is an evolutionally conserved protein kinase cascade involved in regulating organ size in vivo and cell contact inhibition in vitro by governing cell proliferation and apoptosis. Deregulation of the Hippo pathway is linked to cancer development. Its first core kinase Warts was identified in Drosophila more than 15 years ago, but it gained much attention when other core components of the pathway were identified 8 years later. Major discoveries of the pathway were made during past several years. The core kinase components Hippo, Salvador, Warts, and Mats in the fly and Mst1/2, WW45, Lats1/2, and Mob1 in mammals phosphorylate and inactivate downstream transcriptional co-activators Yorkie in the fly, Yes-associated protein (YAP) and transcriptional co-activator with ...

2011-01-01

100

Establishment of functional primary cultures of heart cells from the clam Ruditapes decussatus  

British Library Electronic Table of Contents (United Kingdom)

Heart cells from the clam Ruditapes decussatus were routinely cultured with a high level of reproducibility in sea water based medium. Three cell types attached to the plastic after 2?days and could be maintained in vitro for at least 1?month: epithelial-like cells, round cells and fibroblastic cells. Fibroblastic cells were identified as functional cardiomyocytes due to their spontaneous beating, their ultrastructural characteristics and their reactivity with antibodies against sarcomeric ?-actinin, sarcomeric tropomyosin, myosin and troponin T-C. Patch clamp measurements allowed the identification of ionic currents characteristic of cardiomyocytes: a delayed potassium current (I K?slow) strongly suppressed (95%) by tetraethylammonium (1?mM), a fast inactivating potassium current (I K?fas...

2011-01-01

101

Enhanced inactivation of bacteria by metal-oxide nanoparticles combined with visible light irradiation  

British Library Electronic Table of Contents (United Kingdom)

AbstractBackground In recent years nano-metaloxides which easily penetrate into the cells with special interest due to their higher chemical reactivity as compared to that of similar materials in the bulk form. Of particular interest are nano-TiO2 and ZnO, which have been widely used for their bactericidal and anticancerous properties. Purpose The aim of the present study was to examine the bactericidal properties of nano-TiO2 and ZnO combined with visible light on S. aureus and S. epidermitis, known for their high prevalence in infected wounds. Study Using the technique of electron-spin resonance (ESR) coupled with spin trapping, we examined the ability of TiO2 and ZnO nanoparticle suspensions in water to produce reactive oxygen species (ROS) with and without visible light irradiation. Th...

2011-01-01

102

Effect of processing of dates into date juice concentrate and appraisal of its quality characteristics  

British Library Electronic Table of Contents (United Kingdom)

Date palm (Phoenix dactylifera) is widely cultivated in Kutch district of Gujarat and the fruits are harvested at immature stage before the onset of monsoon to prevent spoilage. The immature date fruits with less commercial value were used for processing into date juice concentrate. Immature dates were crushed and treated with 0.1% pectinase enzyme for 120 min to obtain maximum juice. Date juice was found to be rich in reducing sugars (16.1%) and total sugars (18.3%). Juice was pasteurized at 85?C to inactivate the enzyme, cooled and centrifuged at 3000 rpm to get clear juice. The juice was concentrated in a thin film evaporator to a total soluble solids (TSS) of 76?Brix in 2 passes. Chemical composition of date juice during different stages of concentration was determined. Date juice conc...

2010-01-01

103

Ectopic mineralization of connective tissue in Abcc6-/- mice: effects of dietary modifications and a phosphate binder - a preliminary study  

British Library Electronic Table of Contents (United Kingdom)

Please cite this paper as: Ectopic mineralization of connective tissue in Abcc6-/- mice: effects of dietary modifications and a phosphate binder - a preliminary study. Experimental Dermatology 2008; 17: 203-207. Abstract: Pseudoxanthoma elasticum (PXE), a heritable multisystem disorder, is caused by mutations in the ABCC6 gene. We have developed a murine model for PXE by targeted inactivation of the corresponding mouse gene. A feature of this mouse model is ectopic mineralization of connective tissue capsule surrounding the bulb of vibrissae. This study was designed to investigate the effect of dietary sevelamer hydrochloride (Renagel), a phosphate binder, and specific mineral modifications on ectopic mineralization of connective tissue in Abcc6-/- mice. Three groups were fed a specific di...

2008-01-01

104

Detection of the first gross CDC73 germline deletion in an HPT-JT syndrome family  

British Library Electronic Table of Contents (United Kingdom)

Abstract Hereditary primary hyperparathyroidism (HPT) may develop as a solitary endocrinopathy (FIHP) or as part of multiple endocrine neoplasia Type 1, multiple endocrine neoplasia Type 2A, or hereditary HPT-jaw tumor syndrome. Inactivating germline mutations of the tumor suppressor gene CDC73 account for 14 and 50% of all FIHP and HPT-JT patients, respectively, and have also been found in almost 20% of apparently sporadic parathyroid carcinoma patients. Although more than 60 independent germline mutations have been described, to date no rearrangement affecting the CDC73 locus has been identified. By means of multiplex-PCR we found a large germline deletion affecting the whole gene in a two-generation HPT-JT family. Subsequently array-CGH and specific PCR analysis determined that the muta...

2011-01-01

105

Chromatographic evaluation of microbial activity in biological activated carbon bed; Kuromatoho ni yoru seibutsu kasseitanso ni okeru biseibutsu kassei no hyoka  

Energy Technology Data Exchange (ETDEWEB)

The moment analysis of pulse responses was applied to a biological activated carbon (BAC) bed to evaluate the microbial activity. Glucose and activated carbon fiber (ACF) were employed in experiments as a model tracer and an activated carbon respectively. No significant difference in biodegradation rates of glucose by microorganisms attached on different solid supports such as activated carbon inactivated carbon and glass fibers was observed. However, higher microbial activity was obtained from microorganisms supported on the ACF in terms of the apparent degradation of total organic including metabolic byproducts by microorganisms, since part of the metabolic byproducts was irreversibly deposited onto the ACF. 11 refs., 6 figs.

1996-07-10

106

Biosorption of heavy metal ions on Rhodobacter sphaeroides and Alcaligenes eutrophus H16  

Energy Technology Data Exchange (ETDEWEB)

A fundamental study of the application of bacteria to the recovery of toxic heavy metals from aqueous environments was carried out. The biosorption characteristics of cadmium and lead ions were determined with purple nonsulfur bacteria, Rhodobacter sphaeroides and hydrogen bacteria, Alcaligenes eutrophus H16 that were inactivated by steam sterilization. A simplified version of the metal binding model proposed by Plette et al. was used for the description of meal binding data. The results showed that the biosorption of bivalent metal ions to whole cell bodies of the bacteria was due to monodentate binding to two different types of acidic sites: carboxilic and phosphatic-type sites. The number of metal binding sites of A. eutrophus was 2.4-fold larger than that of R. sphaeroides.

1998-01-15

107

Antimicrobial Edible Apple Films Inactivate Antibiotic Resistant and Susceptible-Campylobacter jejuni-Strains on Chicken Breast  

British Library Electronic Table of Contents (United Kingdom)

Abstract:- Campylobacter jejuni-is the leading cause of bacterial diarrheal illness worldwide. Many strains are now becoming multidrug resistant. Apple-based edible films containing carvacrol and cinnamaldehyde were evaluated for bactericidal activity against antibiotic resistant and susceptible-C. jejuni-strains on chicken. Retail chicken breast samples inoculated with D28a and H2a (resistant strains) and A24a (a sensitive strain) were wrapped in apple films containing cinnamaldehyde or carvacrol at 0.5%, 1.5%, and 3% concentrations, and then incubated at 4 or 23 C for 72 h. Immediately after wrapping and at 72 h, samples were plated for enumeration of viable-C. jejuni. The antimicrobial films exhibited dose- and temperature-dependent bactericidal activity against all strains. Films with ...

2011-01-01

108

The evaluation of risks from radiation  

International Nuclear Information System (INIS)

German translation of the publication 'The evaluation of risks from radiation' published in 1965 by the International Commission on Radiological Protection. In a survey, genetic and somatic risks from radiation are presented and explained. (HP).

1977-01-01

110

Role of Mast Cells in Early and Delayed Radiation Injury in Rat Intestine  

Science.gov (United States)

... mast cell staining; ref. 16). The severity of structural radiation injury was assessed using a histopathological radiation injury score ... ...

111

Radionuclide X-ray fluorescence analysis. 1: Excitation of X-ray fluorescense radiation by nuclear radiation  

Science.gov (United States)

The principles of radionuclide excitation of X-ray fluorescence radiation and its application in

1972-01-01

112

Radionuclide X-ray fluorescence analysis. 2: Detection of the X-ray fluorescence radiation excited by radionuclide radiation  

Science.gov (United States)

This investigation describes the technique for the detection of the X-ray fluorescent radiation

1972-01-01

113

Radiation protection - an overview of the concept for radiation protection at work and the concept for environmental radiation protection  

International Nuclear Information System (INIS)

This book gives an overview of the entire field of radiation protection with the subject areas radioactivity, X-rays, UV radiation, laser beams and high-frequency electromagnetic fields. It deals graphically with the most important physical notions, the incidence, origin, properties and biological effects of types of radiation, administrative and practical protection measures and the code of rules governing them. Apart from fundamentals of radiation protection the emphasis on the following: natural radiation exposure, radiation exposure to radon, disaster relief plans in the environment of nuclear plant, the precautionary radiation protection system evolved after Chernobyl, radiation exposure through UV radiation devices, radio, RF communication, radar, microwave ovens and high-voltage transmission ...

1993-01-01

116

THE ENVIRONMENTAL MANAGEMENT AND CO-ORDINATION ACT, 1999  

Wastenet

Subject to the provisions of the Radiation Protection Act, the Authority, on the advice of ...(f) in collaboration with the Radiation Protection Board, conduct an ionising radiation monitoring programme and ...or document kept under the control of the Radiation Protection Board.

124

Application of gamma radiation  

International Nuclear Information System (INIS)

Described and discussed in this paper are radiation processes and their advantages over the conventional techniques. Radiation sterilization of medical products, food irradiation, wood plastic composites, and radiation treatment of sewage and waste waters are presented. The Philippine experience in using these technologies, its problems and barriers are also given. (ELC).

1985-12-10

128

Radiobiology  

International Nuclear Information System (INIS)

This text-book (electronic book - multi-media CD-ROM) constitutes a course-book - author's collection of lectures. It consists of 13 lectures in which the reader acquaints with the basis of radiobiology: Introduction to radiobiology; Physical fundamentals of radiobiology; Radiation of cells; Modification of radiation damage of cells; Reparation of radiation damage of cells; Radiation syndromes and their modification; Radiation injury; Radiation damage of tissues; Effect of radiation on embryo and fetus; Biological effects of incorporated radionuclides; Therapy of acute irradiation sickness; Delayed consequences of irradiation; Radiation oncology and radiotherapy. This course-book may be interesting for students, post-graduate students of chemistry, biology, physics, medicine as well as for teachers, scientific workers ...

129

Radiation Therapy in Treating Patients With Prostate Cancer  

Science.gov (United States)

Prostate Cancer; Psychosocial Effects of Cancer and Its Treatment; Radiation Toxicity; Sexual Dysfunction and Infertility

2011-09-13

131

NAME=\\  

Wastenet

... Radiation Protection Products and Equipment Find and compare a variety of radiation protection products and equipment on the world's largest environmental industry portal. View product ...

133

Functions of mammalian Cdc7 kinase in initiation/monitoring of DNA replication and development  

Energy Technology Data Exchange (ETDEWEB)

Cdc7 kinase plays an essential role in firing of replication origins by phosphorylating components of the replication complexes. Cdc7 kinase has also been implicated in S phase checkpoint signaling downstream of the ATR and Chk1 kinases. Inactivation of Cdc7 in yeast results in arrest of cell growth with 1C DNA content after completion of the ongoing DNA replication. In contrast, conditional inactivation of Cdc7 in undifferentiated mouse embryonic stem (ES) cells leads to growth arrest with rapid cessation of DNA synthesis, suggesting requirement of Cdc7 functions for continuation of ongoing DNA synthesis. Furthermore, loss of Cdc7 function induces recombinational repair (nuclear Rad51 foci) and G2/M checkpoint responses (inhibition of Cdc2 kinase). Eventually, p53 becomes highly activated and the cells undergo massive p53-dependent apoptosis. Thus, defective origin activation in mammalian cells can generate DNA replication checkpoint signals. ...

2003-11-27

134

Effect of propylbenzilylcholine mustard on contraction and radioligand binding parameters of muscarinic receptors in guinea pig ileum  

Energy Technology Data Exchange (ETDEWEB)

The receptor occupancy-biological effect relationship for muscarinic receptors in guinea pig ileal smooth muscle has been studied by comparison of radioligand binding and contractile response. Muscarinic receptors in homogenates of ileal smooth muscle were labeled with (/sub 3/H)-1-Quinuclidinyl benzilate. Treatment with propylbenzilylcholine mustard (PrBCM), to inactivate irreversibly muscarinic receptors, caused a large dose dependent rightward shift of the dose-response curve to three agonistic furtrethonium derivatives with a concomitant decrease in maximal response. Using those data, the fraction of receptors remaining unoccupied (q-values) and true affinity constants (-log K/sub A/-values) were calculated. Exposure to 20 or 60 nM PrBCM for 15 minutes resulted in a 39% and a 61% reduction in specific (/sup 3/H)-1-Quinuclidinyl benzilate binding sites respectively to be compared with a 62% and a 85% decrease expected from calculated q-values. K/sub A/-values ...

1987-10-26

135

Standards and guidances for limiting ionizing radiation exposure  

Energy Technology Data Exchange (ETDEWEB)

This chapter is concerned with standards and guidances for limiting radiation exposures. It is divided into three sections, each of which has several parts. Section 1: Ionizing Radiation -- Standards and Guidances Applicable to the Public: Part A, Radiation Protection Standards; Part B, Environmental Radiation Standards; Part C, Exempt Levels of Radioactivity; Part D, Protective Action Guides for Accidents. Section 2: Ionizing Radiation -- Standards Applicable to the Workplace. Section 3: Medical and Other Standards.

1992-12-31

136

Radiation protection in the operating room  

International Nuclear Information System (INIS)

On the basis of legally provided area dose measurements and time records of fluoroscopic examinations during the operation, radiation doses to medical personnel and patients are evaluated. Adequate radiation protection measures and a careful behaviour in the operating room keep the radiation exposure to the personnel below the maximum permissible exposure. Taking into account the continuous personnel radiation monitoring and medical supervision, radiation hazards in the operating room can be considered low.

137

Survey of Radiation Protection Education and Training in Finland in 2003  

Energy Technology Data Exchange (ETDEWEB)

The current state and need for radiation protection training in Finland have been surveyed by the Radiation and Nuclear Safety Authority STUK. The survey sought to determine whether the current requirements for radiation protection training had been met, and to promote radiation protection training. Details of the scope and quality of present radiation protection training were requested from all educational institutes and organizations providing radiation protection training. The survey covered both basic and further training, special training of radiation safety officers, and supplementary training. The questionnaire was sent to 77 educational organization units, 66 per cent of which responded. Radiation workers and radiation safety officers were asked about radiation protection ...

2004-07-01

138

The benefits of low level radiation  

Energy Technology Data Exchange (ETDEWEB)

The assumed linear relationship between exposure to radiation and cancer incidence is questioned in this article. The current research data on radiation effects at the cellular level is reviewed, as are epidemiological studies of background radiation effects and health effects of populations exposed to low levels of radiation exposure via employment or medical treatments. Statistics reveal that threshold levels currently in force need to be reviewed. Some evidence of beneficial effects of low level radiation exposure effects of low level radiation exposure is also presented, and so regulations should be reviewed at an international level. (UK).

1997-06-01

139

Stimulated radiation of high - current relativistic electron beams  

International Nuclear Information System (INIS)

The most propagated mechanisms of stimulated radiation of electron beam such as Cherenkov one-particle and collective effects, ondulator and magnetic bremsshrahlung radiations, Doppler anomalous effect, Thompson and Raman scattering and radiation are discussed. Relation of spontaneous radiation mechanisms of individual electron and stimulated radiation effects in electron beams has been elucidated, grounds of linear electrodynamics of radiative beam instabilities are stated, and main mechanisms of their nonlinear stabilization are elucidated as well. Various simulated processes in electron beams are considered from the unique point of view using a simple mathematical apparatus and such physical laws as conservation and Newton laws.

1987-01-01

140

Radiation protection. A guide for scientists and physicians  

International Nuclear Information System (INIS)

This manual was written for individuals who wish to become qualified in radiation protection as an adjunct to working with sources of ionizing radiation or using radionuclides in the field of medicine. It provides the radiation user with information needed to protect himself and others and to understand and comply with governmental and institutional regulations regarding the use of radionuclides and radiation machines. It is designed for a wide spectrum of users, including physicians, research scientists, engineers, and technicians. It should be useful also to radiation safety officers, members of radiation safety committees, and others who are responsible for the proper use of radiation sources, although they may not be working with the sources directly. The presentation in this manual is designed to obviate the need for reviews of atomic ...

141

Combining satellite data and models to estimate cloud radiative effect at the surface and in the atmosphere  

British Library Electronic Table of Contents (United Kingdom)

Abstract Satellite measurements and numerical forecast model reanalysis data are used to compute an updated estimate of the cloud radiative effect on the global multi-annual mean radiative energy budget of the atmosphere and surface. The cloud radiative cooling effect through reflection of short wave radiation dominates over the long wave heating effect, resulting in a net cooling of the climate system of - 21 Wm-2. The short wave radiative effect of cloud is primarily manifest as a reduction in the solar radiation absorbed at the surface of - 53 Wm-2. Clouds impact long wave radiation by heating the moist tropical atmosphere (up to around 40 Wm-2 for global annual means) while enhancing the radiative cooling of the atmosphere over other regions, in particular higher latitudes and sub-trop...

2011-01-01

142

Biological effects of electromagnetic radiation in the microwave range  

Energy Technology Data Exchange (ETDEWEB)

The book examines current experimental and clinical knowledge concerning the biological and biophysical effects of electromagnetic radiation, particularly that in the microwave range. The biophysical bases of the interaction of electromagnetic radiation with matter are reviewed with emphasis on biological systems, and the effects of radiation on critical biological systems, including the nervous, reproductive, visual and blood-forming systems are compared. Data concerning the lethal effects of nonionizing radiation is presented and characteristics of the effects of electromagnetic radiation on the whole mammalian organisms are examined. Various reactions of the neuroendocrine system to electromagnetic radiation are described, with particular attention given to the adrenal system, and the combined effects of ionizing and microwave radiation ...

1980-01-01

143

[The indicators of biological age and accelerated aging in liquidators of the consequences of radiation emergency].  

Science.gov (United States)

The biological age (BA) of the majority of the liquidators of the consequences of the radiation accidents in the Navy and of the liquidators of the Chernobyl' APS accident exceeds the medium standard and the DBA (due BA). The index of the BA can be a characteristic of the influence of the social-hygienic factors on the health condition of the Special Risk Subunit--the liquidators of the consequences of the radiation accidents. It was established, that the radiation influence concerns to the factors dramatically increasing the BA and the rate of senescence of the liquidators of the consequences of the radiation accidents. PMID:21809627

2011-01-01

144

The THz Radiation from Undulator  

Science.gov (United States)

The experimental device for generation of undulator radiation in terahertz wavelength region by use of undulator with ferromagnets is created. The device is based on a beam of a microtron with the energy 7.5 MeV. The radiation wavelength is 200 mu. Registered spontaneous radiation has a power 10{sup -6} W at a current of a beam 2 mA in a pulse. With the optical resonator, in a mode, the amplification of 6% is received, that in sometimes is more than the expected value. This effect is explained as a result of partial coherence of radiation.

2010-02-03

145

Study of emission of Cerenkov radiation by tachyons  

Energy Technology Data Exchange (ETDEWEB)

The emission of Cerenkov radiation by tachyons has been examined by using the reduced expansions of superluminal electromagnetic fields in terms of standard helicity representation of Poincare group. It has been shown that the tachyons emit Cerenkov radiation through their coupling only with subluminal electromagnetic fields and that a charged tachyon can emit Cerenkov radiation only in the media in which it travels with a velocity lower than that of light while in the usual medium in which its velocity is more than that of light, it will never emit Cerenkov radiation.

1983-01-01

146

Radiation facility with electron accelerator of the Institute for Nuclear Research of Ukraine, Kiev  

International Nuclear Information System (INIS)

Characteristics of the Ukrainian NSA NRI radiation facility for scientific researches and developments of industrial radiation technology are performed. Parts of the facility, design peculiarities of technical tools are described. Biological protection of the facility and radiation protection system, transport line, systems of technical provision and radiation measurements are discussed

2003-02-01

147

Radiation exposure of the population of the GDR by X-ray diagnostics  

International Nuclear Information System (INIS)

The radiation burden of the people of the GDR in relation to biomedical radiography altogether as well as organ doses, gonad doses and genetically significant doses in detail are outlined. The concepts of radiation protection and standards of radiographic examination are demonstrated. Possibilities of influencing radiation exposure by scientifically based indication of X-ray examination, application of new and improvement of usual examination techniques are discussed with regard to quality assurance and control. Proposals concerning the reduction of radiation exposure of the GDR population are presented.

1986-01-01

148

Potential Hazards from Neutrino Radiation at Muon Colliders  

CERN Document Server

High energy muon colliders, such as the TeV-scale conceptual designs now being considered, are found to produce enough high energy neutrinos to constitute a potentially serious off-site radiation hazard in the neighbourhood of the accelerator site. A general characterization of this radiation hazard is given, followed by an order-of-magnitude calculation for the off-site annual radiation dose and a discussion of accelerator design and site selection strategies to minimize the radiation hazard.

1999-01-01

149

Model of quantum noise of shadow radiation images  

International Nuclear Information System (INIS)

Correlation characteristics of quantum noise on the shadow radiation image (RI) of the object under nondestructive testing are studied. Mathematical model of RI occasional distortions is derived. The model takes into account the parameters of object under testing and of radiation beam by radiation quanta flux density. The results obtained can be used as a component in the process of investigation of various radiation testing systems

150

Coherent oscillator radiation  

International Nuclear Information System (INIS)

Coherent oscillator radiation is considered. A comparison is made with classical particle radiation with gauss distribution. Decay probability for coherent state in spontaneous radiation is estimated. The method suggested for describing harmonic oscillator allows to separate the effect of classical field radiation from quantum description of particle state within the framework of a self-consistent quantum mechanical problem.

1982-04-01

151

Use of Organic Acids to Inactivate-Escherichia coli-O157:H7,-Salmonella-Typhimurium, and-Listeria monocytogenes-on Organic Fresh Apples and Lettuce  

British Library Electronic Table of Contents (United Kingdom)

Abstract:- This study was undertaken to investigate the antimicrobial effect of organic acids against-Escherichia coli-O157:H7,-Salmonella-Typhimurium, and-Listeria monocytogenes-on whole red organic apples and lettuce. Several studies have been conducted to evaluate organic acids as sanitizers. However, no studies have compared antimicrobial effects of various organic acids on organic fresh produce, including evaluation of color changes of produce. Apples and lettuce were inoculated with a cocktail of 3 strains each of 3 foodborne pathogens provided above and treated with 1% and 2% organic acids (propionic, acetic, lactic, malic, and citric acid) for 0, 0.5, 1, 5, and 10 min. With increasing treatment time and acid concentration, organic acid treatments showed significant reduction compar...

2011-01-01

152

TMPRSS6 rs855791 modulates hepcidin transcription in vitro and serum hepcidin levels in normal individuals.  

Science.gov (United States)

The iron hormone hepcidin is inhibited by matriptase-2, a liver serine-protease encoded by TMPRSS6 gene. Cleaving the BMP-coreceptor hemojuvelin, matriptase-2 impairs the BMP/SMAD signaling pathway, downregulates hepcidin and facilitates iron absorption. TMPRSS6 inactivation causes iron-deficiency-anemia refractory to iron administration both in humans and mice. Genome wide association studies have shown that the SNP rs855791, which causes the matriptase-2 V736A amino acid substitution, is associated with variations of serum iron, transferrin saturation, hemoglobin and erythrocyte traits. Here we show that in vitro matriptase-2 736(A) inhibits hepcidin more efficiently than 736(V). Moreover, in a genotyped population, after exclusion of samples with iron deficiency and inflammation, hepcidin, hepcidin/transferrin saturation and hepcidin/ferritin ratios were significantly lower and iron parameters were consistently higher in homozygotes 736(A) than in 736(V). Our ...

2011-08-26

153

Sertoli cells in culture secrete paracrine factor(s) that inhibit peritubular myoid cell proliferation: identification of heparinoids as likely candidates  

Energy Technology Data Exchange (ETDEWEB)

Conditioned medium from Sertoli cells, prepared from testes of 20-day-old rats, contains component(s) that inhibit the incorporation of (3H)-thymidine into DNA of peritubular myoid cells (PMC) and inhibit the proliferation of PMC. These components are trypsin-resistant, heat-stable compounds having a molecular weight less than 30,000. The active inhibitory components in Sertoli cell conditioned medium are inactivated by treatment with heparinase, but not by treatment with hyaluronidase or chondroitin sulfate lyases. Addition of heparin or heparan sulfate results in inhibition of DNA synthesis by PMC in a dose-dependent manner, whereas other glycosaminoglycans (GAGs) examined (hyaluronic acid, keratan sulfate, and chondroitin sulfate) have no detectable effects. Heparin and heparan sulfate are unique among GAGs tested in inhibiting the characteristic multilayer growth pattern of PMC following the attainment of confluence in serum-rich medium. On the basis of these ...

1991-06-01

154

Limit of pitting corrosion at high-alloyed special steels and NiCrMo alloys in chloride solution; Die Lochkorrosionsbegrenzung bei hochlegierten Sonderedelstaehlen und NiCrMo-Legierungen in Chloridloesung - Einflussfaktoren und Ausmass  

Energy Technology Data Exchange (ETDEWEB)

The phenomenon of the limit of pitting corrosion in direction to positive potentials is studied by potentiokinetic polarization after a jump in the transpassive range and by potentiostatic tests at technical wrought materials and at model alloys of the systems NiCrMo and NiMo in CaCl{sub 2} solution in the concentration range 1 to 9 mol/l chloride at pH-values of 1 to 9 at temperatures of 30 to 110 C. Surface-analytical investigations gives in connection with knowledges from anodic polarization studies directions to the mechanism of the limit of pitting corrosion. Ranges of the limit of pitting corrosion are obtained at materials with a Mo content above 6.5% and contents of chloride of the media above 2 mol/l chloride. Increasing temperatures, increasing contents of chloride and sulfate shift the potential of the limit of pitting corrosion being always above 0.2 V (SCE) at potentiostatic determination to noble direction. There are indications that the mechanisms of limit of pitting ...

2001-08-01

155

Ectopic expression of Cux1 is associated with reduced p27 expression and increased apoptosis during late stage cyst progression upon inactivation of Pkd1 in collecting ducts  

British Library Electronic Table of Contents (United Kingdom)

Abstract Polycystic kidney diseases (PKD) are inherited disorders characterized by fluid-filled cysts primarily in the kidneys. We previously reported differences between the expression of Cux1, p21, and p27 in the cpk and Pkd1 null mouse models of PKD. Embryonic lethality of Pkd1 null mice limits its study to early stages of kidney development. Therefore, we examined mice with a collecting duct specific deletion in the Pkd1 gene. Cux1 was ectopically expressed in the cyst lining epithelial cells of newborn, P7 and P15 Pkd1CD mice. Cux1 expression correlated with cell proliferation in early stages of cystogenesis, however, as the disease progressed, fewer cyst lining cells showed increased cell proliferation. Rather, Cux1 expression in late stage cystogenesis was associated with increased ...

2011-01-01

156

Development of a novel mouse tk{sup +/-} embryonic stem cell line for use in mutagenicity studies  

Energy Technology Data Exchange (ETDEWEB)

A tk{sup +/-} mouse embryonic stem (ES) cell line, designated 1G2, has been created in which one allele of the thymidine kinase (tk) gene was inactivated by targeted homologous recombination. This line is an analog of the mouse lymphoma tk{sup +/-} L5178Y cell line, which is used widely to assess the mutagenicity of chemical agents. Treatment of 1G2 cells with the alkylating agent N-ethyl-N-nitrosourea (ENU) resulted in a dose-related increase in tribluorothymidine-resistant colonies. Mutant frequencies of 152 and 296 per 10{sup 6} cells were determined for 0.1 and 0.3 mg/ml doses of ENU, compared with a spontaneous mutant frequency of 15 per 10{sup 6} cells. The data indicate that tk{sup +/-} 1G2 ES cells may be useful for the creation of a transgenic mouse model for assessing in vivo mutation using an endogenous autosomal gene. 45 refs., 2 figs., 1 tab.

1996-12-31

157

Study of particles trapped by a magnetic field  

Science.gov (United States)

A new type of radiation which occurs when particles are accelerated in the field of a longitudinal wave and in a transverse magnetic field is studied. The characteristics of such spontaneous radiation are obtained, and the influence of collective effects on the radiation is analyzed. The application of the findings to the theory of free electron lasers is discussed. 8 references.

1986-01-01

159

Risk of cancer after low doses of ionising radiation: retrospective cohort study in 15 countries  

UK PubMed Central (United Kingdom)

Objectives To provide direct estimates of risk of cancer after protracted low doses of ionising radiation and to strengthen the scientific basis of radiation protection standards for environmental,...Full Text Available

2005-07-09

160

Radiation therapy alone versus radiation therapy and chemotherapy in the management of Hodgkin's disease.  

UK PubMed Central (United Kingdom)

Forty-four patients with histologically proven Hodgkin's disease underwent initial treatment with extended-field radiation therapy. Nineteen of these patients also received combination chemotherapy....Full Text Available

1990-02-01

161

Radiation exposure due to X-rays of the hip joint in babies  

International Nuclear Information System (INIS)

Exact anatomic knowledge about the location of the gonads and the application of corresponding measures of radiation protection are the preconditions for an efficient reduction of the danger of a possible genetic damage as a result of radiation exposition during X-ray examination of the hip joint of newborns. (VJ).

162

Multiscale registration of planning CT and daily cone beam CT images for adaptive radiation therapy  

UK PubMed Central (United Kingdom)

Adaptive radiation therapy (ART) is the incorporation of daily images in the radiotherapy treatment process so that the treatment plan can be evaluated and modified to maximize the amount of radiation...Full Text Available

2009-01-01

163

Lagranzheva dinamika kollektivnykh vzaimodejstvij v potokakh diskretnykh izluchatelej. (Lagrange dynamics of collective interactions in flows of discrete radiators).  

Science.gov (United States)

Analytical method of theoretical simulation of collective hydrodynamic instabilities of intensive flows of discrete radiators, interacting with each other only through the coherent fields of their spontaneous radiation in corresponding media was suggested...

1989-01-01

164

Granite Countertops and Radiation | Radiation Protection | US EPA  

Wastenet

... Top of page Testing Radiation coming from granite countertops results from natural radioactive material in the granite. Identifying the presence and concentration of radioactive elements in granite requires expensive and sophisticated portable instruments or laboratory equipment. These instruments and equipment require proper calibration, and interpretation of ...

165

Are natural radioactive materials dangerous  

International Nuclear Information System (INIS)

The different radiation loads caused by natural and artificial radionuclides are compared in this paper. This examples will serve to illustrate that the problem of population exposure to radiation can only be solved in consideration of all components and to show which effects of the radiation from natural sources are of special importance in this connexion. (orig./AK).

1974-09-23

166

A radiator of electromagnetic waves with a combined shape of generatrices  

British Library Electronic Table of Contents (United Kingdom)

The problem of optimizing a horn radiator of electromagnetic waves for the reflection coefficient and the coefficient of transformation of the fundamental mode into higher order modes is solved. Optimization is performed by means of selecting a combined shape of the radiator generatrices.

2008-01-01

167

Using ICCD as a fast optical switch to measure harmonic super-radiation from an optical klystron in a storage ring  

International Nuclear Information System (INIS)

An optical klystron is built in the 800 MeV electron storage ring at University of Science and Technology of China for harmonic super-radiation generation. In single bunch operation mode the repetition rate of the spontaneous radiation pulses is about 4.533 MHz, and the repetition rate of the seed laser pulses is about 3 Hz, while the radiation pulse duration is 300 ps. For measuring harmonic radiation a high on/off ratio ICCD is used as an optical switch to reject spontaneous radiation pulses of high repetition rate

2001-07-01

168

The medical exposures to ionizing radiations, it is a world priority in radiation protection  

International Nuclear Information System (INIS)

The document published under A/63:46 and titled report of the scientific committee of United Nations for the study of ionizing radiations effects, gives the situation of the fifty sixth session of the committee that stood at Vienna from the 10. to 18. july 2008. In the chapter 3 of this report the writers summarize the strategic planning and the working program of the scientific committee for the period 2009-2013. They note that the committee worry about the inadequate means, particularly in personnel. The priorities for the given period will be the medical exposure of patients, the radiation levels and the effects of energy production, the exposure to natural radiation sources and the improvement of the understanding of the effects of the low doses radiation exposure. (N.C.)

169

x - NASA Technical Reports Server  

Science.gov (United States)

Mar 1, 2011 ... Radionuclide X-ray fluorescence analysis. 2: Detection of the X-ray fluorescence radiation excited by radionuclide radiation ...

170

VOLUME I11 IMISSION SYSTEM PERFORMANCE - NASA Technical Report ...  

Science.gov (United States)

Nov 8, 2010 ... Ihring Mission 11, the radiation dosimetry measurement system functioned normally and provided data on the Earth's trapped radiation belts ...

171

Treatment of persons exposed in radiation accidents or nuclear explosions. Omhaendertagande av skadade vid radiakolyckor och kaernvapenexplosioner  

Energy Technology Data Exchange (ETDEWEB)

The report gives general principles of treatment and care of casualties caused by radiation accidents or nuclear explosions.

1991-01-01

172

The importance of radiation quality for optimisation in radiology  

UK PubMed Central (United Kingdom)

Selection of the appropriate radiation quality is an important aspect of optimisation for every clinical imaging task in radiology, since it affects both image quality and patient dose. Spreadsheet...Full Text Available

174

Tachyon Cerenkov radiation  

Energy Technology Data Exchange (ETDEWEB)

By proposing the four-dimensional, reciprocity transformations the appropriate condition for superluminal electromagnetic Cerenkov radiation is obtained by introducing the hypothesis that tachyons possess vector energy and scalar momentum.

1985-09-01

175

Solar Cell Radiation Response near the Interface of Different ...  

Science.gov (United States)

... Solar Cell Radiation Respinnse Near the Interface o~f fliffprerv- ... 5 4. CALCUTl-ATED SOLAR CELL RLSPONSE FOR VARIOUS BASE MATERIALS ...

1971-11-01

176

Relationship of Optical Coating on Thermal Radiation ...  

Science.gov (United States)

drical Enclosures Using a Numerical Ray Tracing Technique. NASA. TM-I02527, 1990 . Buckley, H.: Radiation from the Interior of a Reflecting Cylinder. Philos. ...

177

References | Radiation Protection | US EPA  

Wastenet

...References | Radiation Protection | US EPA This page provides links to the reference material on EPA's Radiation Protection Web site. U.S. EPA/...OAR/ORIA/Radiation Protection Division Jump to main content. Radiation Protection Contact Us Search: All EPA This Area You are here: EPA Home ... Radiation Protection References PageName Technical Users General Public Reporters Librarians Students/Teachers PROGRAMS TOPICS REFERENCES References The Reference Section provides general material that support the ...other sections of EPA's Radiation Protection Web site. You will find links within the information to related pages throughout the Radiation Protection , EPA ...

178
179

Radiation deamination of tetracycline. [Gamma radiation  

Energy Technology Data Exchange (ETDEWEB)

The fundamental product of tetracycline hydrochlorine gamma radiolysis was separated in its solid state. From the results of spectroscopic studies it has been established that it is des-N,N-dimethylaminotetracycline.

1980-01-01

180

Radiation Damage Calculations for the FUBR and BEATRIX Irradiations of Lithium Compounds in EBR-II and FFTF  

Energy Technology Data Exchange (ETDEWEB)

Radiation Damage Calculations for the FUBR and BEATRIX Irradiations of Lithium Compunds in EBR-II and FFTF

1999-05-01

181

Onclas U9800 - NASA Technical Report Server (NTRS)  

Science.gov (United States)

the probability of its spontaneous radiation de-excitation increases. ... consider spontaneous radiation transitions. We will examine the ...

182

Numerical analysis of methane-air combustion considering radiation effect  

Energy Technology Data Exchange (ETDEWEB)

Turbulent premixed methane-air combustion in a cylindrical chamber is numerically simulated considering radiation effect. Reaction rates are considered as minimum rates between Arrhenius rates and eddy break up rates. A five step reduced mechanism is used. Turbulent modeling is done via standard k-{epsilon} model imposed by empirical inlet boundary conditions. Source terms of energy equation consist of reaction rates and radiation effects. The discrete ordinate method (DOM) is employed to solve the radiative transfer equation (RTE) and the weighted sum of gray gas model (WSGGM) is imposed to consider radiation effect of non-gray gases. The results indicate that in the case of turbulent combusting flows, the effect of radiation of gases can affect the temperature and species concentrations. The numerical results obtained considering radiation effect are closer to ...

2008-12-15

183

Numerical analysis of methane-air combustion considering radiation effect  

International Nuclear Information System (INIS)

Turbulent premixed methane-air combustion in a cylindrical chamber is numerically simulated considering radiation effect. Reaction rates are considered as minimum rates between Arrhenius rates and eddy break up rates. A five step reduced mechanism is used. Turbulent modeling is done via standard k-? model imposed by empirical inlet boundary conditions. Source terms of energy equation consist of reaction rates and radiation effects. The discrete ordinate method (DOM) is employed to solve the radiative transfer equation (RTE) and the weighted sum of gray gas model (WSGGM) is imposed to consider radiation effect of non-gray gases. The results indicate that in the case of turbulent combusting flows, the effect of radiation of gases can affect the temperature and species concentrations. The numerical results obtained considering radiation effect are closer to the ...

2008-12-01

184

Multifunctional, Boron-Foam Based Radiation Shielding  

Science.gov (United States)

PROPOSAL NUMBER: 04 B3.09-7744. SUBTOPIC TITLE: Radiation Shielding to Protect Humans. PROPOSAL TITLE: Multifunctional, Boron-Foam Based ...

185

Mathematical Analysis of Three Free-Electron-Laser Issues  

Science.gov (United States)

... iFfficiency-en- enhanced spontaneous radiation at the free-electron- ... as enhanced spontaneous radiation at the free-electron-laser wavelength. ...

1990-09-30

186

Equipment hardening and hardness assurance  

International Nuclear Information System (INIS)

The introduction of tolerance to radiation (''radiation-hardness'') into large electronic systems is one of the major tasks to which this Handbook will be put. The practices recommended here for inculcating radiation-tolerance in equipment require advanced physical modeling techniques, precise engineering procedures, and firm assurance procedures. The degree to which these procedures should be used in an equipment project can be measured by the severity of the raw radiation environment, the desired reliability of the system, and the requirement of that project for radiation-sensitive technologies. The balance of device/circuit design versus shielding will depend on whether the radiation is highly penetrating -- as in isotope handling or military environments -- or readily attenuated, as in space. In this chapter the authors have attempted to summarize the ...

187

Enhanced coherent undulator radiation from bunched electron beams  

International Nuclear Information System (INIS)

When energetic bunches of electrons traverse an undulator field, they can spontaneously emit radiation both coherently and incoherently. Although it has generally been assumed that undulator radiation is incoherent at wavelengths short compared to the longitudinal size of the electron bunch, several recent observations have proved this assumption false. Furthermore, the appearance of coherent radiation is often accompanied by a significant increase in radiated power. Here we report observations of strongly enhanced coherent spontaneous radiation together with direct measurements, using transition radiation techniques, of the electron distributions responsible for the coherent emission. We also report demonstrated enhancements in the predicted spontaneous radiated power by as much as 6x10"4 using electron bunch compression. copyright 1996 ...

1995-09-28

189

ESR study in radiation damage in pyrimidines. 3-year comprehensive progress report  

International Nuclear Information System (INIS)

General mechanisms of radiation damage to biomolecules was studied by using substituted pyrimidines, particularly barbituric acid derivatives.

190

Differences in synchrotron radiation induced gas desorption from stainless steel and aluminium alloy  

CERN Document Server

Differences in synchrotron radiation induced gas desorption from stainless steel and aluminium alloy

1990-01-01

191

Combined Radiation and Thermal Injury after Nuclear Attack  

Science.gov (United States)

... Except for isolated radiation accidents over the ensuing years, little practical experience has been gained in the treatment of thermal injuries ...

2011-05-13

192

Chinese Journal of Lasers (Selected Articles)  

Science.gov (United States)

... spontaneous radiation of amplifiers within a relatively w~de range of ... pulse widths are 20-30ns, while amplified spontaneous radiation pulse ...

1991-12-10

193

An evaluation of planning techniques for stereotactic body radiation therapy in lung tumors  

UK PubMed Central (United Kingdom)

PurposeTo evaluate four planning techniques for stereotactic body radiation therapy (SBRT) in lung tumors.Methods...Full Text Available

2008-04-01

194

uv photobiology: postreplication repair. [Escherichia coli, synchrotron radiation  

Science.gov (United States)

The following topics are discussed: insertion of incorrect bases in DNA; ability of DNA polymerase to copy uv-irradiated DNA; role of enzymes in repair of DNA; effects of uv radiation on molecular weight of DNA; photoreactivation; repair of DNA in Escherichia coli and xp cells following uv radiation; and synchrotron radiation studies on DNA repair. (HLW)

1978-01-01

197

Tumorigenic and tumoricidal actions of ionizing radiations  

Energy Technology Data Exchange (ETDEWEB)

The book is divided into two approximately equal parts. The first four chapters are relatively lengthy and cover the basic principles of radiation biology, carcinogenesis and therapy, along with a brief introduction to radiological physics to orient the reader without background in this specialized related discipline. The remainder consists of twenty-four relatively brief chapters, each covering the radiation biology of a specific organ, tissue, or systems tissues, with emphasis on the tumorigenic and tumoricidal action of ionizing radiations.

1983-01-01

198

The influence of stray radiation on image quality  

International Nuclear Information System (INIS)

The present state of knowledge on the influence of stray radiation on image quality and its physical description and quantification is summarized. Experimental results on the influence of physical parameters on the fraction of scattered radiation and the effect of scatter reduction by air gap technique and secondary radiation grids are committed. Open theoretical and practical problems and the limitations of common methods of scatter reduction are pointed out. (author).

201

Surprising collectivity in neutron-rich iron isotopes  

International Nuclear Information System (INIS)

... VDPEAZ (Bonn 2010 issue) NUCLEAR PHYSICS AND RADIATION PHYSICS

2010-03-15

206

Space Radiation Detector with Spherical Geometry  

Science.gov (United States)

A particle detector is provided, the particle detector including a spherical Cherenkov detector, and

2011-01-01

208

Solar Radiation Pressure Binning for the Geosynchronous Orbit  

Science.gov (United States)

Orbital maintenance parameters for individual satellites or groups of satellites have traditionally

2011-01-01

209

Self-filling and self-purging apparatus for detecting spontaneous radiation from substances in fluids  

Energy Technology Data Exchange (ETDEWEB)

Disclosed herein is a radiation detector providing for the in situ automatic sampling of fluids containing substances emitting radiation, especially Cerenkov radiation. The detector permits sampling within well casings and is self-purging such that no additional provisions must be established for the storage and disposal of contaminated fluids.

1993-01-01

211

Radiological equipment for emergencies  

Energy Technology Data Exchange (ETDEWEB)

A brief guide to training and equipment needed to effectively manage victims of radiation accidents. (DT)

1985-01-01

215

Radiation-annealing hardening of vanadium  

International Nuclear Information System (INIS)

A study is made of the mechanical properties of vanadium irradiated with fast neutrons up to dose 8.6.10"-"4 dpa, as a function of the temperature of post-radiation annealing. The radiation-annealing hardening (RAH) effect is observed at 300"oC, in agreement with previous studies. It is established for the first time that RAH is accompanied by fall in ductility. A phenomenological model is described which explains the dependence of RAH on radiation dose and temperature, as well as on the content of chemically active alloying impurities. (author).

216

Radiation processing used in forestry in Thailand  

Energy Technology Data Exchange (ETDEWEB)

A summary is presented of research being carried out in Thailand on the preparation of irradiation-impregnated wood.

1981-01-01

217

Radiation effects on the shoot tip culture of chrysanthemum  

International Nuclear Information System (INIS)

Japanese (Mar 1974). Japan Mabuchi, Toshio Kuwada, Hikaru . Kagawa Univ.,

220

Radiation and fetal brain development  

International Nuclear Information System (INIS)

(4 Sep 1986). United Kingdom Zamenhof, Stephen . California Univ., Los

221

Radiation Protection of the Organism (Selected Chapters)  

Science.gov (United States)

... biologically important compounds is sharply lowered with passage of the solutions to the cell an organ, where their sensitivity ...

1970-12-11

222
224

Possibility of production of new superheavy nuclei in complete fusion reactions  

International Nuclear Information System (INIS)

... of Sciences (Poland) [5.48 Megabytes] NUCLEAR PHYSICS AND RADIATION

2008-09-01

225

Nuclear physics with a free electron laser  

International Nuclear Information System (INIS)

... radiation parity photonuclear reactions polarized beams resonance

227

Multi-spectral schottky barrier infrared radiation detection array  

Energy Technology Data Exchange (ETDEWEB)

A multi-spectral Schottky barrier infrared detector array in which individual pixels of radiation from a remote radiating object are detected by two or more Schottky barrier infrared radiation detectors each having a different spectral response so as to provide a ''color'' discrimination for the array.

1983-12-27

228

Multi-spectral schottky barrier infrared radiation detection array  

International Nuclear Information System (INIS)

A multi-spectral Schottky barrier infrared detector array in which individual pixels of radiation from a remote radiating object are detected by two or more Schottky barrier infrared radiation detectors each having a different spectral response so as to provide a ''color'' discrimination for the array.

230

Kinetics of low-temperature radiation hardening of metallic materials under irradiation  

British Library Electronic Table of Contents (United Kingdom)

A formula is obtained which describes the kinetics of low-temperature radiation hardening caused by creation of dislocation loops of interstitial type during irradiation. The radiation hardening of aluminum and vanadium is estimated using this formula and results of experiments on studying processes of nucleation and growth of interstitial dislocation loops in these materials by transparent electron microscopy. It is shown that the proposed formula is valid for description of the kinetics of low-temperature radiation hardening.

2011-01-01

232

Infrared processes in the auroral zone  

International Nuclear Information System (INIS)

... aurorae carbon dioxide emission spectra infrared radiation nitrogen nitrogen

8432-01-01

234

Induced radiation during scattering of channeled electrons and positrons by point defects  

Energy Technology Data Exchange (ETDEWEB)

In scattering of channeled particles by point defects and in emission of gamma rays in the spontaneous-radiation spectral region conditions are attained where the momentum transferred to the defect is taken up by the crystal as a whole. This leads to coherent and interference effects in the radiation from the crystal defects. When the longitudinal momentum transferred is zero, an induced radiation effect appears in the transitions between the states of transverse motion.

1984-12-01

238

ISR site  

CERN Document Server

A last look at the green field, in the triangular wedge of land stray radiation near the CERN accelerators.

1965-01-01

239

Free radicals in lysozyme reacted with peroxidizing methyl linoleate  

International Nuclear Information System (INIS)

... electron spin resonance gamma radiation lipids lyophilization lysozyme radicals

240

Four cases of bowel perforation following radiation therapy for cervical cancer  

Energy Technology Data Exchange (ETDEWEB)

External radiation dose exceeded 5,000 rad in three cases, and intravaginal radiation dose was 5,000 rad in one case. Radiation damage including perforation was seen in the end of ileus in one case, in the sigmoid and rectum in two cases, and in the end of ileus, sigmoid and rectum in the last case. Satisfactory results were obtained by the removal of the ileocecum in the case of the damage in the end of the ileus. However, only colostomy was performed for the damage in the sigmoid and rectum.

1984-10-01

241

Experts' discussion on the possibility of quantification of the radiation hazard  

International Nuclear Information System (INIS)

Due to the intensity and vast number of subjects, this Bremen experts' discussion, too, could discuss only part of the problem of the possibilitiy to quantify the radiation hazard. One preliminary result is that there is no scientific proof of the harmlessness of radiation exposure during normal operation of a nuclear power plant, either within the plant or in its vicinity. Other results are that some important questions can not be answered yet, and that there are important hints on the dangers even of low radiation doses. (GL).

1978-01-01

244

Effective dose equivalent in nuclear medicine investigations  

International Nuclear Information System (INIS)

... radiation hazards hazards health hazards MEDICINE. SOMATICALLY

1984-05-07

247

Development of a real-time, neutron and gamma dosimeter  

Energy Technology Data Exchange (ETDEWEB)

In 1998, research began at Idaho National Engineering and Environmental Laboratory to investigate the application of {sup 6}Li and {sup 7}Li isotopes to the measurement of neutron and gamma radiation. Various size pairs of {sup 6}Li and {sup 7}Li based detectors were exposed to mixed neutron and gamma radiation. Experiments demonstrated that these detectors could be used to measure low level neutron radiation in the presence of high level gamma radiation. (author)

2001-07-01

248

Development of a real-time, neutron and gamma dosimeter  

International Nuclear Information System (INIS)

In 1998, research began at Idaho National Engineering and Environmental Laboratory to investigate the application of "6Li and "7Li isotopes to the measurement of neutron and gamma radiation. Various size pairs of "6Li and "7Li based detectors were exposed to mixed neutron and gamma radiation. Experiments demonstrated that these detectors could be used to measure low level neutron radiation in the presence of high level gamma radiation. (author)

2001-06-10

249

Cooperative spontaneous emission from two different atoms  

International Nuclear Information System (INIS)

The total radiation rate, angular distribution of the emitted energy and photon correlations of the cooperative spontaneous radiation from two atoms with different resonance frequencies and spontaneous decay rates are calculated. Contrary to the case of two identical atoms oscillations appear in the total radiation rate and the spatial distribution of the total number of emitted photons differs from the single-atom radiation pattern. The effect of the dipole-dipole near-field interaction on the time evolution of the atomic system is discussed. (author).

1986-01-01

251

Comparing two strategies of dynamic intensity modulated radiation therapy (dIMRT) with 3-dimensional conformal radiation therapy (3DCRT) in the hypofractionated treatment of high-risk prostate cancer  

UK PubMed Central (United Kingdom)

BackgroundTo compare two strategies of dynamic intensity modulated radiation therapy (dIMRT) with 3-dimensional conformal radiation therapy (3DCRT) in the setting of hypofractionated...Full Text Available

252

Cluster-loop structure influence on molybdenum radiation hardening  

International Nuclear Information System (INIS)

Results on defect structure study and degree of molybdenum radiation hardening irradiated by fission neutrons and medium energy alpha-particles are presented. It is shown that molybdenum irradiation by alpha-particles and neutrons leads to different degree of material hardening for the same damage level. It is established that molybdenum radiation hardening is mainly defined by radiation defect clusters visible in electron microscope whose coefficient of rigidity depends on their size. 5 refs.; 6 figs.; 2 tabs. (author).

1990-05-22

258

About tachyons  

International Nuclear Information System (INIS)

... Part A: The electromagnetic radiation of a charged tachyon. Part B: Some

259

ASE FILE  

Science.gov (United States)

radionuclide X-ray fluorescence analysis: the resolving power of the ... The radiation detectors used in radionuclide X-ray fluorescence ...

261

Theory of edge radiation  

CERN Document Server

We formulate a complete theory of Edge Radiation based on a novel method relying on Fourier Optics techniques. Similar types of radiation like Transition Undulator Radiation are addressed in the framework of the same formalism. Special attention is payed in discussing the validity of approximations upon which the theory is built. Our study makes consistent use of both similarity techniques and comparisons with numerical results from simulation. We discuss both near and far zone. Physical understanding of many asymptotes is discussed. Based on the solution of the field equation with a tensor Green's function technique, we also discuss an analytical model to describe the presence of a vacuum chamber. In particular, explicit calculations for a circular vacuum chamber are reported. Finally, we consider the use of Edge Radiation as a tool for electron beam diagnostics. We discuss Coherent Edge ...

2008-01-01

262

Radiative corrections to the atomic levels in a periodic electromagnetic field  

Energy Technology Data Exchange (ETDEWEB)

The influence of a periodic electromagnetic field on the radiative corrections to the atomic energy levels is studied for the case of ''strong fields'' for which the interaction between the atom and field is of the order or greater than the radiative effects. The analysis is carried out on the basis of the Schwinger-Dirac equation for the propagation function of a bound electron in the field and on the basis of the density matrix in the Furry representation. It is shown that in the strong field approximation the radiative shifts and widths are manifest as radiative corrections to the quasi-energies. In super-high resolution experiments intensity effects in the radiative corrections to the atomic levels are obtained in the case of single-photon resonance. Some multiphoton processes are condidered by taking into account the effect of the field on ...

1982-12-01

263

Biological radiation effects  

International Nuclear Information System (INIS)

The stages of processes leading to radiation damage are studied, as well as, the direct and indirect mechanics of its production. The radiation effects on nucleic acid and protein macro moleculas are treated. The physical and chemical factors that modify radiosensibility are analysed, in particular the oxygen effects, the sensibilization by analogues of nitrogen bases, post-effects, chemical protection and inherent cell factors. Consideration is given to restoration processes by excision of injured fragments, the bloching of the excision restoration processes, the restoration of lesions caused by ionizing radiations and to the restoration by genetic recombination. Referring to somatic effects of radiation, the early ones and the acute syndrome of radiation are discussed. The difference of radiosensibility observed in mammalian cells and main observable alterations in tissues and ...

1976-01-01

264

A study on the real-time radiation dosimetry measurement system based on optically stimulated luminescence  

International Nuclear Information System (INIS)

The optically stimulated luminescent (OSL) radiation dosimeter technically surveys a wide dynamic measurement range and a high sensitivity. Optical fiber dosimeters provide capability for remote monitoring of the radiation in the locations which are difficult-to-access and hazardous. In addition, optical fiber dosimeters are immune to electrical and radio-frequency interference. In this paper, a novel remote optical fiber radiation dosimeter is described. The optical fiber dosimeter takes advantage of the charge trapping materials CaS:Ce, Sm that exhibit OSL. The measuring range of the dosimeter is from 0.1 to 100 Gy. The equipment is relatively simple and small in size, and has low power consumption. This device is suitable for measuring the space radiation dose and also can be used in high radiation dose condition and other dangerous radiation occasions. ...

2008-05-01

265

Radiological concepts in radiotherapy  

International Nuclear Information System (INIS)

The atomic explosions in Hiroshima and Nagasaki made the name radiation itself become a nightmare. Notwithstanding this, radiation continued to serve the mankind specially in diagnosis of several human diseases and in the treatment of intractable malignancies. With their latest research tools biologists have now shown a significant shift in the earlier paradigm; even the concept that radiation initiates cancer appears to be no longer tenable. On the contrary, selective radiation doses inhibit growth of cancer cells and radiation in combination with many chemotherapeutic drugs, radiosensitizing chemicals and/or hyperthermia, is emerging as a new modality for cancer treatment which offers high therapeutic advantages. In addition, the deleterious effects of radiation can now be strategically counter poised by the use of many drugs and chemicals. This has been ...

266

The influence of scattered radiation on recording systems and quality-assurance test parameters  

International Nuclear Information System (INIS)

Scattered radiation generated in patient and imaging system has to be considered when quality-assurance tests involve dose detection or image-quality estimations. Measurement of automatic-exposure control dose can be altered by backscattering from intensifying screens of more than 10% and the equipment transmission factor can be overestimated up to a factor of 10 when only primary radiation is used. The sensitivity of intensifying screens depends on the angle of incidence of the radiation and so primary and scattered radiation are detected differently. The quality-control aspects of anti-scatter grids are discussed. (author).

1988-02-23

267

The influence of scattered radiation on recording systems and quality-assurance test parameters  

International Nuclear Information System (INIS)

Scattered radiation generated in patient and imaging system has to be considered when quality-assurance tests involve dose detection or image-quality estimations. Measurement of automatic-exposure control dose can be altered by backscattering from intensifying screens of more than 10% and the equipment transmission factor can be overestimated up to a factor of 10 when only primary radiation is used. The sensitivity of intensifying screens depends on the angle of incidence of the radiation and so primary and scattered radiation are detected differently. The quality-control aspects of anti-scatter grids are discussed. (author).

268

Study of emission of Cerenkov radiation by tachyons  

International Nuclear Information System (INIS)

The emission of Cerenkov radiation by tachyons has been examined by using the reduced expansions of superluminal electromagnetic fields in terms of standard helicity representation of Poincare group. It has been shown that the tachyons emit Cerenkov radiation through their coupling only with subluminal electromagnetic fields and that a charged tachyon can emit Cerenkov radiation only in the media in which it travels with a velocity lower than that of light while in the usual medium in which its velocity is more than that of light, it will never emit Cerenkov radiation. (author).

269

Standard radiation monitoring at Sendai nuclear power station  

International Nuclear Information System (INIS)

Standard radiation monitoring has been conducted at Sendai nuclear power station for the purpose of estimation of 'source activity' during refueling outage and evaluation of countermeasures to reduce dose rate. Selected objects of the monitoring are radiation dose rate at maintenance area, radiation field at each equipment and piping, coolant chemistry and plant operation condition. Monitored data indicates that 'source activity' variation can be estimated to some extent using influential factors, and that evaluation of change of loose crud activity, which is presumed to be represented by the dose rate at letdown heat exchanger, is necessary to further explain change in radiation field at main work area. (author).

270

Somatic radiation risk in X-ray diagnostics  

Energy Technology Data Exchange (ETDEWEB)

The authors give a survey of the somatic radiation risk in X-ray diagnostics. A somatic dose index is calculated for different examination methods containing the organ doses to the red bone marrow, the lung, the female breast, and the thyroid gland and evaluating their somatic significance. If this somatic dose index by which the individual radiation risk is described, is multiplied by the examination frequencies per year in the German Federal Republic, one gets the somatically significant dose index, which is a measure of the collective somatic radiation risk. In this sense, mammography has the highest, and dental radiography the lowest collective radiation risk.

1983-12-01

271

Somatic radiation risk in X-ray diagnostics  

International Nuclear Information System (INIS)

The authors give a survey of the somatic radiation ris in X-ray diagnostics. A somatic dose index is calculated for different examination methods containing the organ doses to the red bone marrow, the lung, the female breast, and the thyroid gland and evaluating their somatic significance. If this somatic dose index by which the individual radiation risk is described, is multiplied by the examination frequencies per year in the German Federal Republic, one gets the somatically significant dose index, which is a measure of the collective somatic radiation risk. In this sense, mammography has the highest, and dental radiography the lowest collective radiation risk. (orig.).

1983-01-01

272

Radiation-stimulated diffusion of aerosols  

Energy Technology Data Exchange (ETDEWEB)

The diffusion coefficient of particles in radioactive gases has been calculated with account of random wandering of aerosols (occurrence of local fields affecting the particles; recoils accompanying radiation emitted by particles, etc.). To determine the diffusion coefficient, the method of Fokker-Planck equation derivation was used. A formula is presented for calculating the radiation-stimulated diffusion coefficient. A linear growth of the diffusion coefficient with radioactivity is noted according to the formula, the diffusion coefficient is mainly determined by the field in the radiation damage region. The aerosol radioactivity may result in a more rapid deposition of aerosols in the pipelines and aerosol purification systems. The diffusion rate grows not only in the presence of intrinsic radioactivity but in case of external radiation exposure as well.

1984-04-01

273

Radiation-induced chemical modification of wood  

International Nuclear Information System (INIS)

The results of theoretical and experimental investigations, describing the effect of ionizing radiation on wood and its main components and methods for production of wood-plastic composites by means of radiation-induced chemical modification are generalized. Domestic and foreign experience in their production is systematized; physico-mechanical characteristics of new material, simulation and calculation of irradiating devices, as well as calculation and experimental study of #gamma#-radiation attenuation both by wood material and by wood of different species are given. Gamma sources ("6"0Co isotope, a hot loop of a nuclear reactor) as well as electron accelerators are considered as ionizing radiation sources.

1985-01-01

274

RADSOLVER: a computer program for calculating spectrally-dependent radiative heat transfer in solar cavity receivers  

Energy Technology Data Exchange (ETDEWEB)

RADSOLVER is a computer program which calculates the radiation energy transport in cavity type receivers having an arbitrary number of apertures through which collimated beams of solar radiation enter. In contrast to the common assumption of gray (or semi-gray) surfaces used in the modeling of radiation transport, RADSOLVER accounts for the wavelength-dependence of emission, absorption and reflection with a band model of the radiative properties. It is intended that this report serve both as an instruction manual for the use of the RADSOLVER code and a vehicle for presenting the underlying theory. Illustrative examples along with input and output are presented.

1981-09-01

275

Practice and experience of occupational exposure control in the outages of Daya Bay Nuclear Power Plant  

International Nuclear Information System (INIS)

Outage is a specific period of time for radiation protection in a nuclear power plant, in which the radiation risk and collective dose are both at the highest level. In this article, the practice and experience of occupational exposure control in the outages of Daya Bay Nuclear Power Plant are introduced through following aspects: early involvement in outage preparation by radiation protection service, control of source term, radiation protection and safety management in the outage implementation processes, the effectiveness of the plant's safety management network and overall involvement of all staffs of the plant, experience feedback and continuous improvement in radiation protection management, etc

2004-05-01

276

New concepts in risk assessment for patients with radiological treatment  

International Nuclear Information System (INIS)

In radiation risk assessment it must be differentiated between somatic and genetic effect on the one hand as well as between stochastic and non-stochastic effect on the other. According to definitions of the ICRP report 26 the limit for the dose equivalent of all tissues prevents non-stochastic radiation effects. With stochastic radiation effects probably exist no threshold doses; therefore the ALARA principle must be applied concerning radiation protection. The individual risk by stochastic radiation effects in its linear, linear-quadratic and quadratic extrapolations, respectively, is discussed in detail. The effective stochastic dose equivalent (H/sub eff/) as well as collective dose and collective damage are outlined.

1986-01-01

277

Evaluation of the residual radiation field in the proton accelerator facility of the Proton Engineering Frontier Project (PEFP) in Korea  

British Library Electronic Table of Contents (United Kingdom)

In Korea, the Proton Engineering Frontier Project (PEFP) is building a proton linear accelerator facility with energy up to 100MeV and a beam current of 20mA. In this study, a radiation field after shutdown in the accelerator facility of the PEFP was evaluated for the purpose of the radiation shielding by using MCNPX code. A facility modeling was performed for the accelerator tunnel building, accelerator chain, target rooms and beam experiment hall. And radiation source terms were evaluated in the facility. With this facility, model and radiation source terms, the concentration of 41Ar was evaluated and the cooling time satisfying regulation in Korea was calculated.

2007-01-01

278

Difference between delayed radiation-necroses of the cerebral hemispheres and midline: its bearing in radiation therapy  

Energy Technology Data Exchange (ETDEWEB)

Delayed cerebral necroses after irradiation are to be divided into hemispheric and midline lesions, as they differ from each other in several aspects. Apart from the symptoms, they are differing in the duration of latency, in the course and prognosis, and also with regard to morphology. Though there is no doubt that radiation tolerance of cerebral midline structures is relatively limited, on biological grounds, evidence of a difference between the tolerated doses could not be given from the existent inhomogeneous radiation data, with the help of the NSD-concept. Radiation planning for the region of the head, nevertheless, carefully should avoid in every case to involve the structures of the cerebral midline.

1980-08-01

279

Decommissioning and dismantling. Examination of the radiation hardening of electronic components. Final report  

International Nuclear Information System (INIS)

Remote-controlled handling systems are required for work to be done in the decommissioning and dismantling of nuclear facilities. These systems are equipped with electronic devices suitable for use in working environments affected by ionizing radiation. The publication explains the step-wise progress achieved for improving the radiation resistance of electronic devices with the example of a four-quadrant controlling device for the motors of a manipulator. The radiation resistance of the device could be enhanced to radiation energies of 5.500 Gy. This means that a manipulator vehicle equipped with this controlling device can take up to approx. 15 kGy all in all, taking into account its own shielding properties. (DG).

280

Comparison and analysis of results of ? radiation level investigation around Daya Bay  

International Nuclear Information System (INIS)

Investigations were carried out of radiation level around Daya Bay for three times since the construction and operation Daya bay Nuclear Power Station and Lingao Nuclear Power Station in Guangdong province in the period of 1988 to 2000. As shown by the investigation, the radiation levels both in the field and indoors remains unchanged by and large but slightly higher than before on the roads. Also this paper gives the analysis of variations in radiation levels form site to site and from time to time. It was shown that, for environmental ? radiation levels measurements, typical measuring sites have significant impact on the meaning results. (authors)

2003-08-01

281

Biological Research for Radiation Protection  

International Nuclear Information System (INIS)

The work scope of 'Biological Research for the Radiation Protection' had contained the research about ornithine decarboxylase and its controlling proteins, thioredoxin, peroxiredoxin, S-adenosymethionine decarboxylase, and glutamate decarboxylase 67KD effect on the cell death triggered ionizing radiation and H_2O_2(toxic agents). In this study, to elucidate the role of these proteins in the ionizing radiation (or H_2O_2)-induced apoptotic cell death, we utilized sensesed (or antisensed) cells, which overexpress (or down-regulate) RNAs associated with these proteins biosynthesis, and investigated the effects of these genes on the cytotoxicity caused by ionizing radiation and H_2O_2(or paraquat). We also investigated whether genisteine(or thiamine) may enhance the cytotoxic efficacy of tumor cells caused by ionizing radiation (may enhance the preventing effect ...

282

Synchrotron radiation from electron beams in plasma-focusing channels.  

Science.gov (United States)

Spontaneous radiation emitted from relativistic electrons undergoing betatron motion in a plasma-focusing channel is analyzed, and applications to plasma wake-field accelerator experiments and to the ion-channel laser (ICL) are discussed. Important similarities and differences between a free electron laser (FEL) and an ICL are delineated. It is shown that the frequency of spontaneous radiation is a strong function of the betatron strength parameter a(beta), which plays a role similar to that of the wiggler strength parameter in a conventional FEL. For a(beta) > or approximately 1, radiation is emitted in numerous harmonics. Furthermore, a(beta) is proportional to the amplitude of the betatron orbit, which varies for every electron in the beam. The radiation spectrum emitted from an electron beam is calculated by averaging the single-electron spectrum over the electron distribution. This leads to a ...

2002-05-20

283

Somatic and genetic radiation exposure of the patient in digital subtraction angiography (DSA)  

International Nuclear Information System (INIS)

The somatic and genetic radiation exposure of patients undergoing Digital Subtraction Angiography (DSA) and traditional Film Arteriography (FA) of cranial, cervical, thoracic and abdominal vascular territories are compared. The radiation doses absorbed within the critical organs - red bone marrow, lung, thyroid gland and female breast - and in the gonads were measured using an anthropomorphic Alderson phantom. A Somatic Dose Index was calculated in order to estimate the somatic radiation risk. The somatic radiation exposure depends upon the location of the critical organs with respect to the entrance site of the x-ray beam, and can be reduced by an appropriate choice of the angiographic projection. Under this condition, the radiation exposure of the patient during DSA can be lower than during FA. For renal DSA an a.p. projection, the use of an abdominal compression device and ...

1986-01-01

284

Radiation therapy in the treatment of hilar cholangiocarcinoma  

International Nuclear Information System (INIS)

The incidence of hilar cholangiocarcinoma is very rare worldwide. Radical resection is the only prognostic factor for long survival in patients with hilar cholangiocarcinoma. Postoperative radiation therapy can improve local control and survival rates for patients with palliative resection, but it remains controversial in patients with radical resection. Biliary drainage can effectively release bile duct obstruction for the majority of patients with locally advanced disease, and may even prolong survival when combined with radiation therapy. Radiation therapy includes extrernal beam therapy alone, external beam therapy with intraluminal brachytheapy and new radiation technique, such as three dimentional conformal therapy and intensity modulated radiation therapy. The propective randomized clinical study is needed for further investigation in the role of combined modality therapy ...

2007-10-01

285

Radiation receiver. Strahlungsempfaenger  

Energy Technology Data Exchange (ETDEWEB)

The purpose of the invention is to improve a radiation receiver, consisting of a hollow body with an opening for the entry of radiation and a ceramic absorber situated in the hollow body, which absorbs the radiation energy entering through the opening, and emits it as thermal radiation to a heat medium, so that a higher efficiency can be achieved. According to the invention, the problem is solved by the fact that the absorber consists of ceramic material on the side towards the solar radiation, which has a low emission value and a high absorption value, and that the side of the absorber towards the heat medium has ceramic material of high emission value and low absorption value. This ensures that reradiation is prevented near the opening of the hollow body, and that the solar energy entering is largely absorbed in the hollow body.

1981-10-01

286

Radiation hardening of smart electronics  

International Nuclear Information System (INIS)

Microprocessor based ''smart'' pressure, level, and flow transmitters were tested to determine the radiation hardness of this class of electronic instrumentation for use in reactor building applications. Commercial grade Complementary Metal Oxide Semiconductor (CMOS) integrated circuits used in these transmitters were found to fail at total gamma dose levels between 2500 and 10,000 rad. This results in an unacceptably short lifetime in many reactor building radiation environments. Radiation hardened integrated circuits can, in general, provide satisfactory service life for normal reactor operations when not restricted to the extremely low power budget imposed by standard 4--20 mA two-wire instrument loops. The design of these circuits will require attention to vendor radiation hardness specifications, dose rates, process control with respect to radiation hardness factors, and ...

287

Procedure for radiation dose control in irradiated tissues during electron-beam therapy  

International Nuclear Information System (INIS)

The invention refers a procedure of radiation dose control in irradiated tissues during electron-beam therapy. It aims at meeting the planned radiation dose for diseased tissues and taking care of the healthy ones. Therefore, the dose distribution required is determined before irradiation in consideration of such factors as energy-dependence of detector sensitivity, self-absorption within the tissue, and relative biological effectiveness. Furthermore, the expected intensity distribution of secondary quantum radiation excited in the irradiated tissue is calculated. A radiation detector for local resolution is used for registration. During irradiation the calculated intensity distribution is compared with the measured one. The invention is applicable in radiation therapy with monoenergetic electron beams.

1984-11-08

288

Ionizing radiation effect on sealant properties  

International Nuclear Information System (INIS)

Presented are the investigation results of electrophysical and physico-mechanical properties of KLF-20, Viksint U-4-21, Viksint KT-73, UF-7-21, KG-184, KL-4, KL-16SE-305, VIAT-1 and PPK-21 sealants, irradiated with sources of continuous and pulse #gamma#-radiation, as well as pulse #gamma#-neutron radiation. It is shown that electrophysical and physico-mechanical properties of sealants after irradiation by continuous #gamma#-radiation up to 10"6 doses and pulse gamma-neutron radiation with neutron fluence of 10"1"3 neutron/cm"2 and #gamma#-radiation dose of 10"4R do not practically change. Electric conductivity and tangent of the angle of dielectric losses increase in the process of irradiation. Electric conductivity depends on irradiation type, is proportional to dose rate and does not depend on temperature and pulse duration.

289

Compare analysis of efficiency of using of digital and analog regimes of registration of radiation in radiometric systems of radiation thickness measuring  

International Nuclear Information System (INIS)

A consideration is given to the problem of selecting optimized methods of radionuclide radiation registration during the control of the objects with essential changes in thickness. Adequate model of information signal formation is developed and analyzed for the case of the existence of an inertial link of the system with the dead time of a noncontinued type. The boundary values of radiation thickness and radiation flux intensity that divide the priority of using either digital or analog registration modes are revealed. The method is found for the full correction of a systematic error of flux intensity measurement because of the dead time of the apparatus. To control the objects with essential variation of thickness the method of selective measurement of radiation intensity is proposed

290

Basic mechanisms of radiation effects in the natural space radiation environment  

Energy Technology Data Exchange (ETDEWEB)

Four general topics are covered in respect to the natural space radiation environment: (1) particles trapped by the earth`s magnetic field, (2) cosmic rays, (3) radiation environment inside a spacecraft, (4) laboratory radiation sources. The interaction of radiation with materials is described by ionization effects and displacement effects. Total-dose effects on MOS devices is discussed with respect to: measurement techniques, electron-hole yield, hole transport, oxide traps, interface traps, border traps, device properties, case studies and special concerns for commercial devices. Other device types considered for total-dose effects are SOI devices and nitrided oxide devices. Lastly, single event phenomena are discussed with respect to charge collection mechanisms and hard errors. (GHH)

1994-06-01

291

The effects of cosmic radiation on implantable medical devices  

Energy Technology Data Exchange (ETDEWEB)

Metal oxide semiconductor (MOS) integrated circuits, with the benefits of low power consumption, represent the state of the art technology for implantable medical devices. Three significant sources of radiation are classified as having the ability to damage or alter the behavior of implantable electronics; Secondary neutron cosmic radiation, alpha particle radiation from the device packaging and therapeutic doses(up to 70 G{gamma}) of high energy radiation used in radiation oncology. The effects of alpha particle radiation from the packaging may be eliminated by the use of polyimide or silicone rubber die coatings. The relatively low incidence of therapeutic radiation incident on an implantable device and the use of die coating leaves cosmic radiation induced secondary neutron single event upset (SEU) as the main ...

1996-12-31

292

Packaging materials for use in radiation processing of foods  

International Nuclear Information System (INIS)

In radiation processing of food, the product often has to be prepackaged to prevent microbial recontamination during and after irradiation. The packaging material is exposed to radiation during radiation processing and radiation stability is a key consideration in the selection of packaging materials. The effects of ionizing radiation on many food packaging materials at the dose levels recommended for food precessing can be minimized by selecting appropriate radiation resistant materials. It is important to select materials in which chemicals formed as a result of the radiation treatment do not migrate and interact with the food, affecting its organoleptic and toxicological aspects. It is also important to select materials in which the physical properties are not altered to the extent they cannot resist damage during commercial production, ...

293

Method and system for determining depth distribution of radiation-emitting material located in a source medium and radiation detector system for use therein  

Energy Technology Data Exchange (ETDEWEB)

A method, system and a radiation detector system for use therein are provided for determining the depth distribution of radiation-emitting material distributed in a source medium, such as a contaminated field, without the need to take samples, such as extensive soil samples, to determine the depth distribution. The system includes a portable detector assembly with an x-ray or gamma-ray detector having a detector axis for detecting the emitted radiation. The radiation may be naturally-emitted by the material, such as gamma-ray-emitting radionuclides, or emitted when the material is struck by other radiation. The assembly also includes a hollow collimator in which the detector is positioned. The collimator causes the emitted radiation to bend toward the detector as rays parallel to the detector axis of the detector. The collimator may be a hollow cylinder ...

2003-03-04

294

[Somatic radiation risk in conventional tomography of the skull and thorax].  

Science.gov (United States)

The somatically significant dose index can be considered as a measure for the somatic radiation risk to which the population is exposed. Figures are stated for conventional tomography of the skull and thorax. These are compared with the corresponding data for other x-ray examinations, especially computerised tomography. PMID:7134769

1982-10-01

295

[Malignant transformation of human fibroblasts by neutrons and by gamma radiation: Relationship to mutations induced  

Energy Technology Data Exchange (ETDEWEB)

A brief overview if provided of selected reports presented at the International Symposium on Molecular Mechanisms of Radiation- and Chemical Carcinogen-Induced Cell Transformation held at Mackinac Island, Michigan on September 19-23, 1993.

1993-12-31

296

X-ray dose enhancement effects  

International Nuclear Information System (INIS)

A brief description of the physical process of dose enhancement effects produced by X-ray radiation on materials is given, with emphasis on the influence on electronic devices. The damages caused by X-ray radiation dose enhancement is more serious than that of #gamma#-ray with higher energy.

297

What Parents Should Know about Medical Radiation Safety in Interventional Radiology  

Science.gov (United States)

... Amount Background Radiation Blood vessel central line, PICC (peripherally inserted central catheter) or port placement, simple 0.4 mSv ...

298

Variation in the Definition of Clinical Target Volumes for Pelvic Nodal Conformal Radiation Therapy for Prostate Cancer  

UK PubMed Central (United Kingdom)

PurposeWe conducted a comparative study of Clinical Target Volume (CTV) definition of pelvic lymph nodes by multiple GU radiation oncologists looking at the levels...Full Text Available

2009-06-01

299

The use of EPID-measured leaf sequence files for IMRT dose reconstruction in adaptive radiation therapy  

UK PubMed Central (United Kingdom)

For intensity modulated radiation treatment (IMRT) dose reconstruction, multileaf collimator (MLC) log files have been shown applicable for deriving delivered fluence maps. However, MLC log files are...Full Text Available

2008-11-01

300

The relationship of time and space  

CERN Document Server

We show that, in addition to radiation travelling at the speed of light, QED theory predicts a second type of radiation with an infinite velocity. We also show that charge, as it appears in the Dirac equation, may have a triune nature.

2004-01-01

301

Terminal-differential algorithm for identification of local non homogeneity in article  

International Nuclear Information System (INIS)

Terminal-differential algorithm for identification of local nonhomogeneities in items under control is developed on the basis of measurements of X-ray or gamma-radiation weakening. The algorithm may be applied by developing radiation schemes of nondestructive control, identifying inadmissible inclusions in the object under study

302

Targeted nanoparticles that deliver a sustained, specific release of paclitaxel to irradiated tumors  

UK PubMed Central (United Kingdom)

To capitalize on the response of tumor cells to ionizing radiation, we developed a controlled-release nanoparticle drug delivery system using a targeting peptide that recognizes a radiation-induced...Full Text Available

2010-06-01

303

Somatic radiation risk in conventional tomography of the skull and thorax  

Energy Technology Data Exchange (ETDEWEB)

The somatically significant dose index can be considered as a measure for the somatic radiation risk to which the population is exposed. Figures are stated for conventional tomography of the skull and thorax. These are compared with the corresponding data for other X-ray examinations, especially computerised tomography.

1982-10-01

304

Somatic radiation risk in conventional tomography of the skull and thorax  

International Nuclear Information System (INIS)

The somatically significant dose index can be considered as a measure for the somatic radiation risk to which the population is exposed. Figures are stated for conventional tomography of the skull and thorax. These are compared with the corresponding data for other X-ray examinations, especially computerised tomography. (orig.).

1982-01-01

305

Simvastatin ameliorates radiation enteropathy development after localized, fractionated irradiation by a protein C-independent mechanism  

UK PubMed Central (United Kingdom)

BackgroundMicrovascular injury plays a key role in normal tissue radiation responses. Statins, in addition to their lipid-lowering effects, have vasculoprotective...Full Text Available

2007-08-01

306

Shield-verification survey of a large hot cell at the FFTF  

Energy Technology Data Exchange (ETDEWEB)

This paper describes a radiation shield verification survey of a large hot cell at the Fast Flux Test Facility (FFTF). The following aspects of the shield test are discussed: description of the FFTF; description of the hot cell; the test procedures; radiation protection, and the test results.

1980-01-01

307

Radiative transfer in a solar absorbing particle laden flow  

Science.gov (United States)

A possible receiver configuration is a cavity in which a falling sheet of solid particles is directly irradiated by the concentrated solar flux passing through the aperture. Regardless of the particular geometry, the radiative transfer within the falling particle curtain must be studied in order to determine the net radiative heating rate for the particles. A discrete ordinate radiative transfer model has been developed to predict the radiative coupling within the falling particle curtain. The model determines how much energy is absorbed by the particles, how much is transmitted to the rear wall of the receiver, and determines the effects of particle scattering and thermal emission on the net radiation absorbed by the particles. The model accounts for the directional nature of the radiation field, particle scattering, and the wavelength dependence of the optical ...

1985-11-01

308

Radiation, adriamycin, and skin reactions: effects of radiation and drug fractionation, hyperthermia, and tetracycline. [X rays  

Energy Technology Data Exchange (ETDEWEB)

The effect of adriamycin in combination with radiation on the skin reactions of mouse feet has been examined under a variety of experimental conditions including: (a) hyperthermic treatment of the foot immediately following adriamycin administration, with the former given either just before or just after x irradiation, and (b) fractionated treatments of drug and radiation in a variety of sequences over an 18-day period. In the case of the most severe hyperthermic treatment, no increased radiation reactions were observed in the presence of adriamycin. However, in the case of the less severe hyperthermic treatment a small but significant increase in skin reactions was observed. In the study of fractionated drug and radiation treatments, an enhancement of reaction in those animals receiving combined modality treatment over those receiving radiation alone was seen in those groups where ...

1981-06-01

309

Radiation risks for medical applications  

International Nuclear Information System (INIS)

The achievements made in the field of radiation protection over the past 20 years are outlined. Risk analysis as applied to medicine is considered and genetic significant doses, genetic risks, somatic effective doses and somatic risks are discussed. (C.F.).

1980-05-31

310

Radiation modification of vascular prostheses  

International Nuclear Information System (INIS)

The radiation method has been employed for the modification of the surface of vascular prostheses by means of acrylamide. As a result of the treatment, the tightness of the prosthesis walls was improved as well as an increase of surface hydrophilicity. Upon autoclaving, stable binding of polyacrylamide to prostheses is achieved. (author).

311

Radiation decontamination of dry food ingredients and processing aids  

International Nuclear Information System (INIS)

Radiation decontamination of dry ingredients, herbs and enzyme preparations is a technically feasible, economically viable and safe physical process. The procedure is direct, simple, requires no additives and is highly efficient. Its dose requirement is moderate. Radiation doses of 3-10 kGy (0.3-1 mrad) have proved sufficient to reduce the viable counts to a satisfactory level. Ionising radiations do not cause any significant rise in temperature. The flavour, texture or other important technological or sensory properties of most ingredients are not influenced at radiation doses necessary for satisfactory decontamination, and radiation obviates the chemical residue problem. The microflora surviving radiation decontamination of dry ingredients are more susceptible to subsequent antimicrobial treatments. Recontamination can be prevented as the product can be ...

312

Prevention and treatment of functional and structural radiation injury in the rat heart by pentoxifylline and alpha-tocopherol  

UK PubMed Central (United Kingdom)

PurposeRadiation-induced heart disease (RIHD) is a severe side effect of thoracic radiotherapy. This study examined the effects of PTX and α-tocopherol on...Full Text Available

2008-09-01

313

Photosynthetic Response of Seagrasses to Ultraviolet-A Radiation and the Influence of Visible Light Intensity 1  

UK PubMed Central (United Kingdom)

Inhibition of photosynthesis by ultraviolet-A radiation (UV-A, 315-380 nanometers) was examined in three marine angiosperms: Halophila engelmannii Aschers, Halodule wrightii...Full Text Available

1982-02-01

314

Parallel Evolution of a Type IV Secretion System in Radiating Lineages of the Host-Restricted Bacterial Pathogen Bartonella  

UK PubMed Central (United Kingdom)

Adaptive radiation is the rapid origination of multiple species from a single ancestor as the result of concurrent adaptation to disparate environments. This fundamental evolutionary process is considered...Full Text Available

2011-02-01

315

Optimization of extracranial stereotactic radiation therapy of small lung lesions using accurate dose calculation algorithms  

UK PubMed Central (United Kingdom)

BackgroundThe aim of this study was to compare and to validate different dose calculation algorithms for the use in radiation therapy of small lung lesions and to optimize the treatment...Full Text Available

316

Investigation of the radiological safety concerns and medical history of the late Joseph T. Harding, former employee of the Paducah Gaseous Diffusion Plant  

Energy Technology Data Exchange (ETDEWEB)

An ex-employee's claims that inadequate enforcement of radiation safety regulations allowed excess radiation exposure thereby causing his deteriorating health was not substantiated by a thorough investigation.

1981-03-01

317

Inhibited spontaneous emission by a Rydberg atom  

Science.gov (United States)

Spontaneous radiation by an atom in a Rydberg state is inhibited by use of parallel conducting planes to eliminate the vacuum modes at the transition frequency. Spontaneous radiation emission is observed to turn off abruptly at the cutoff frequency of the waveguidelike structure, and the natural lifetime is measured to increase by a factor of at least 20.

1985-11-11

318

Induction of tumors by screening mammography  

International Nuclear Information System (INIS)

Somatic radiation doses are recognized to be possible factors of carcinogenesis. In correctly performed mammography, however, even as screening test, the radiation dose does not reach such an order of magnitude that the benefit of the procedure as to prevention of breast cancer is called into question.

1983-01-01

319

Image-based modeling of tumor shrinkage in head and neck radiation therapy1  

UK PubMed Central (United Kingdom)

Purpose: Understanding the kinetics of tumor growth∕shrinkage represents a critical step in quantitative assessment of therapeutics and realization of adaptive radiation therapy....Full Text Available

2010-05-01

320

Further assessment of the effects of occupational radiation exposure in the United Kingdom Atomic Energy Authority mortality study.  

UK PubMed Central (United Kingdom)

The United Kingdom Atomic Energy Authority mortality study was designed to investigate the relation between exposure to ionising radiation and mortality among the authority's employees. The present...Full Text Available

1987-03-01

321

Fragment condensation of peptides on teflon with radiationally grafted polystyrene  

Energy Technology Data Exchange (ETDEWEB)

In the synthesis of the peptidyl-polymer corresponding to the sequence (57-100) of the ..beta.. chain of human hemoglobin on Teflon with radiationally grafted polystyrene a comparative study was made of different methods of fragment condensation. It was shown that the most effective methods are azide condensation and condensation with the use of complex F.

1986-12-10

322

Fragment condensation of peptides on teflon with radiationally grafted polystyrene  

International Nuclear Information System (INIS)

In the synthesis of the peptidyl-polymer corresponding to the sequence (57-100) of the #beta# chain of human hemoglobin on Teflon with radiationally grafted polystyrene a comparative study was made of different methods of fragment condensation. It was shown that the most effective methods are azide condensation and condensation with the use of complex F.

323

Flashlamp radiation recycling for enhanced pumping efficiency and reduced thermal load  

Energy Technology Data Exchange (ETDEWEB)

A method for recycling laser flashlamp radiation in selected wavelength ranges to decrease thermal loading of the solid state laser matrix while substantially maintaining the pumping efficiency of the flashlamp.

1989-01-01

324

Epidemiological survey of the effects of low level radiation dose: a comparative assessment  

Energy Technology Data Exchange (ETDEWEB)

This volume presents the collations tables of a six volume comparative epidemiological survey of the effects of low level radiation dose. Data are collated for the effects observed in the following irradiated groups:- Preconception irradiation, intra-uterine irradiation, childhood irradiation, adult irradiation. (UK).

1993-10-01

325

Electron spin resonance studies of radiation effects in biological materials. An assessment of current and future research  

Energy Technology Data Exchange (ETDEWEB)

Electron spin resonance spectroscopy can provide a powerful approach to the study of radiation effects in biological materials. This memorandum gives an overview of current and future research. (author).

1987-06-01

326

Effects of small doses of ionizing radiation on human health  

Energy Technology Data Exchange (ETDEWEB)

The risks to human health from small doses of ionizing radiation raise questions which remain largely unanswered. This paper begins by explaining the historical background to this subject; it goes on to discuss recent developments and concludes with a personal view of the dose-reponse relationship. (author).

1997-12-01

327

Effects of small doses of ionizing radiation on human health  

International Nuclear Information System (INIS)

The risks to human health from small doses of ionizing radiation raise questions which remain largely unanswered. This paper begins by explaining the historical background to this subject; it goes on to discuss recent developments and concludes with a personal view of the dose-reponse relationship. (author).

1997-01-01

328

EPR dosimetry in chemically treated fingernails  

UK PubMed Central (United Kingdom)

By using EPR measurements of radiation-induced radicals it is possible to utilize human fingernails to estimate radiation dose after-the-fact. One of the potentially limiting factors in this...Full Text Available

2007-08-01

329

Differential Gene Expression in Primary Human Skin Keratinocytes and Fibroblasts in Response to Ionizing Radiation  

UK PubMed Central (United Kingdom)

Although skin is usually exposed during human exposures to ionizing radiation, there have been no thorough examinations of the transcriptional response of skin fibroblasts and keratinocytes...Full Text Available

2009-07-01

330

Current Role and Future Perspectives of Magnetic Resonance Spectroscopy in Radiation Oncology for Prostate Cancer  

UK PubMed Central (United Kingdom)

Prostatic neoplasms are not uniformly distributed within the prostate volume. With recent developments in three-dimensional intensity-modulated and imageguided radiation therapy, it is possible to treat...Full Text Available

2007-06-01

331

Comparing Radiation Treatments Using Intensity-Modulated Beams, Multiple Arcs and Single Arc  

UK PubMed Central (United Kingdom)

PurposeA dosimetric comparison between multiple static-field intensity-modulated radiation therapy (IMRT), multi-arc intensity-modulated arc therapy (IMAT) and single-arc...Full Text Available

2010-04-01

332

Cellular Senescence, Radiation Damage to Mitochondria, and the Compensatory Response in Ripening Pear Fruits 1  

UK PubMed Central (United Kingdom)

A compensatory response, viz. in vivo recovery from radiation damage to mitochondria, occurs in preclimacteric pear fruits (Pyrus communis L.) treated with ionizing...Full Text Available

1968-07-01

333

CRC handbook of management of radiation protection programs  

Energy Technology Data Exchange (ETDEWEB)

This guidebook organizes the profusion of rules and regulations surrounding radiation protection into a single-volume reference. Employee and public protection, accident prevention, and emergency preparedness are included in this comprehensive coverage. Whenever possible, information is presented in convenient checklists, tables, or outlines that enable you to locate information quickly.

1986-01-01

334

Annealing behavior of radiation damages in metal-silicides  

International Nuclear Information System (INIS)

The annealing behavior of the radiation damage in epitaxial Pd_2Si and NiSi_2 films on Si, due to the implantation of 100 keV Ar ions, is investigated by using the channeling technique with "4He ions. (U.K.).

335

A study of the effects of scattered radiation on radiographic quality and methods of elimination of such radiation  

International Nuclear Information System (INIS)

Many mechanical parts are subjected to stresses and strains that may eventually lead to their failure. In order to prevent the costly delays associated with equipment down-time, many parts have to be tested for weaknesses and defects when machinery is constructed or dismantled for maintenance. These procedures are known as Non-Destructive Testing (NDT) methods. Five types of non-destructive testing methods routinely used are radiographic testing, ultrasonic testing, magnetic particle inspection, liquid penetrant testing and eddy current testing. Out of these five techniques industrial radiography plays an important role in non-destructive testing to reveal interior defects in materials. In radiography almost two-thirds of the radiation reaching the film is scattered radiation which does not form the image of defects. Scattered radiation generated inside and outside a material has a very large effect on sensitivity of flaw ...

1998-02-01

336

A frequency-based approach to locate common structure for 2D-3D intensity-based registration of setup images in prostate radiotherapy  

UK PubMed Central (United Kingdom)

In many radiotherapy clinics, geometric uncertainties in the delivery of 3D conformal radiation therapy and intensity modulated radiation therapy of the prostate are reduced by aligning the...Full Text Available

2007-07-01

337

5 - NASA Technical Reports Server  

Science.gov (United States)

The mission includes a reflected solar instrument retrieving at-sensor .... incoming solar radiation. This direct aerosol radiative forcing (DARF) ... examining the behavior of geosynchronous rocket bodies and non-stabilized payloads as ...

338

20th century and radiation accidents; O seculo XX e os acidentes nucleares  

Energy Technology Data Exchange (ETDEWEB)

The chapter presents the nuclear energy development in 20th century and the most important radiation accidents happened from the point of view of technological risk and high impact consequences: Three Mile Island and Chernobyl.

2006-07-01

339

USSR Report, Electronics and Electrical Engineering.  

Science.gov (United States)

... comparative analysis is made of the sensitivity of two types of spectrometers: instruments employing coherent spontaneous radiation, and classical ...

1985-04-30

340

Two- and three-phonon states in "8"8Sr  

International Nuclear Information System (INIS)

... de-excitation excited states gamma radiation inelastic scattering mev range

341

The structure of the 4.743 MeV state in "8"8Sr  

International Nuclear Information System (INIS)

... states gamma radiation mev range 01-10 photonuclear reactions polarization

342

The advancement of stem cells in radiation medicine  

International Nuclear Information System (INIS)

It may result in acute radiation syndrome after body is exposed to ionizing radiation. The one of long-term effects of irradiation injury is leukemia. The bone marrow cells (BMC) transplantation including stem cells is the only effective therapy for acute radiation syndrome patients. Recently, with the advancement of stem cell research that the stem cells have multipotential and can convert each other, it may supply the new stem source for the irradiation injury patients. At the same time with the further research of radioprotective reagents, the hematopoietic stem cells proliferation after irradiation injury is promoted

2003-02-01

344

Technological press on the environment: comparison of the radiation and conventional processing  

International Nuclear Information System (INIS)

Transformation of row material to the consumption goods proceeds by the succession of various technologies using energy and chemicals. Relative contribution of both factors is broadly varied. The chemical reagents are not per se consumption goods and their production is auxiliary. Maximal usage of chemicals is observed in conventional technologies. On the contrary radiation technology does not need chemicals. Therefore usage of radiation technology leads to diminution of chemical processing and hence to the attenuation of the technological press on the environment. As examples the radiation technological methods in conversion of coal and biomass are considered. (author).

1994-09-11

345

Survey of radiation protection programmes for transport; Etude des programmes de radioprotection pour les transports de matieres radioactives  

Energy Technology Data Exchange (ETDEWEB)

The survey of radiation protection programmes for transport has been jointly performed by three scientific organisations I.P.S.N. (France), G.R.S. ( Germany), and N.R.P.B. (United kingdom) on behalf of the European Commission and the pertaining documentation summarises the findings and conclusions of the work that was undertaken with the principal objectives to provide guidance on the establishment, implementation and application of radiation protection programmes for the transport of radioactive materials by operators and the assessment and evaluation of such programmes by the competent authority and to review currently existing radiation protection programmes for the transport of radioactive materials. (N.C.)

2001-07-01

346

Sunscreen  

Medline Plus

... Animal & Veterinary Cosmetics Radiation-Emitting Products Tobacco Products Drugs Home > Drugs > Resources for You > Information for Consumers (Drugs) Section ...

347

Study of #beta#"- decay of "1"0"1Mo and "1"0"1Tc nuclei  

International Nuclear Information System (INIS)

... radioisotopes coincidence methods energy-level transitions gamma radiation

1998-09-08

348

Stereotactic Radiation Therapy for Brain Tumors  

Medline Plus

... acquired, which we then volumetrically fuse with the 3D image set from the MR. And by doing ...

349

Spontaneous radiation of an electron beam in a free-electron laser with a quadrupole wiggler  

Energy Technology Data Exchange (ETDEWEB)

A calculation is presented of spontaneous radiation emitted by an electron beam passing through a continuously rotating quadrupole magnetic undulator. It is shown that radiation spectrum emitted in forward direction of beam propagation has four peaks, corresponding to four betatron frequencies. Utilizing the Madey theorem, a stimulated emission is calculated and presented as gain versus frequency curves, for different values of the quadrupole magnetic field. A free-electron laser operating at two or three radiation frequencies with a quadrupole magnetic wiggler is suggested.

1986-09-01

350

Single event effects in the pixel readout chip for BTeV  

Energy Technology Data Exchange (ETDEWEB)

In future experiments the readout electronics for pixel detectors is required to be resistant to a very high radiation level. In this paper we report on irradiation tests performed on several preFPIX2 prototype pixel readout chips for the BTeV experiment exposed to a 200 MeV proton beam. The prototype chips have been implemented in commercial 0.25 {micro}m CMOS processes following radiation tolerant design rules. The results show that this ASIC design tolerates a large total radiation dose, and that radiation induced Single Event Effects occur at a manageable level.

2001-12-07

351

Relaxation oscillation of amplified spontaneous radiation pulse emitted from a single-mirror Cu/CuBr laser  

Energy Technology Data Exchange (ETDEWEB)

The relaxation oscillation of the amplified spontaneous radiation pulses emitted from a single-mirror Cu/CuBr laser has been observed for the first time and the experimental characteristics of the relaxation oscillation were obtained. In addition, the spatial and temporal distributions of the light pulse intensity of the amplified spontaneous radiation were also measured and found to be comparatively and uniform. The spatial coherence of the amplified spontaneous radiation was found to be better than that of the laser with the same lasant.

1985-10-01

352

Radiation risk in diagnostic radiology  

International Nuclear Information System (INIS)

An attempt was made to quantify the radiation risk of diagnostic radiology. After a general introduction of terms as radiation damage, radiation risk and effective dose equivalent, based on publications of the ICRP, somatic dose indexes were computed for several radiologic investigations, that comprise organ doses committed to red bone marrow, lung, female breast and thyroid with and without considering the rest of the body. The dose for the rest of the body was assumed to be equal to the dose received by the red bone marrow, that is also distributed over the whole body. Neglecting the exposure of the rest of the body resulted in an insignificant increase in the estimated somatic risk, with its experimental determination not being necessary. (author).

1984-01-01

353

Radiation polymerization of iodmethilate methacriloil lupin in water solutions  

International Nuclear Information System (INIS)

1982. p. 74. Hungary Karimov, A. Musaev, UN Ynusov, G.Sh. Tashkentskij

1982-09-19

354

Radiation dose in computerized tomography  

International Nuclear Information System (INIS)

Dosimetric studies in 80 patients examined with the tomographic device 'Somatom' are reported. The gonad doses are compared to those of conventional radiographic techniques.

355

Radiation control aspects of the civil construction for a high power free electron laser (FEL) facility  

International Nuclear Information System (INIS)

The paper discusses some of the assumptions and methods employed for the control of ionizing radiation in the specifications for the civil construction of a planned free electron laser facility based on a 200 MeV, 5 mA superconducting recirculation electron accelerator. Consideration is given firstly to the way in which the underlying building configuration and siting aspects were optimized on the basis of the early assumptions of beam loss and radiation goals. The various design requirements for radiation protection are then considered, and how they were folded into an aesthetically pleasing and functional building. copyright 1997 American Institute of Physics.

1996-11-06

357

Quick separation of fission product molybdenum and gamma-rays of Mo-102  

International Nuclear Information System (INIS)

... electrophoresis fission products gamma radiation gamma spectra half-life

358

Problems involved in developing an index of harm  

International Nuclear Information System (INIS)

Death as a criterion (age distribution of occupational death; mean loss of life years due to radiation deaths); accidents at work (incidence of accidents of certain degrees of severity); total loss of working days due to accidents; occupational diseases; somatic and genetic radiation effects; radiation effects during pregnancy (incidence of pregnancies, ristes before implantation, hazards to the embryo, hazards to the foetus, total additional risk due to radiation exposure during pregnancy); age and sex dependence of risk figures; attempted formulation of an index of harm. (HP/orig.).

1979-01-01

359

Power Beaming, Orbital Debris Removal, and Other Space ...  

Science.gov (United States)

... transition to couple the emitted spontaneous radiation with the ammonia molecules and thus provide more amplification [2]. ...

2010-03-01

360

Non-gravitational perturbations and satellite geodesy  

Energy Technology Data Exchange (ETDEWEB)

This book presents the basic ideas of the physics of non-gravitational perturbations and the mathematics required to compute their orbital effects. It conveys the relevance of the different problems that must be solved to achieve a given level of accuracy in orbit determination and in recovery of geophysically significant parameters. Selected Contents are: Orders of Magnitude of the Perturbing Forces, Tides and Apparent Forces, Tools from Celestial Mechanics, Solar Radiation Pressure-Direct Effects: Satellite-Solar Radiation Interaction, Long-Term Effects on Semi-Major Axis, Radiation Pressure-Indirect Effects: Earth-Reflected Radiation Pressure, Anisotropic Thermal Emission, Drag: Orbital Perturbations by a Drag-Like Force, and Charged Particle Drag.

1987-01-01

361

N86-28427  

Science.gov (United States)

SPONTANEOUS RADIATION EMITTED BY MOVING TETHERED SYSTEMS. M. Dobrowolny. Istituto Fislca Spazio Interplanetario, CNR Italy ...

363

Lifetime of 2.734 mev Sr"8"8 level  

International Nuclear Information System (INIS)

... range 01-10 nuclei photons radiation sources recoils resonance scattering

366

Ionizing radiation hardening procedure of CCD's  

International Nuclear Information System (INIS)

The procedure of charge-coupled devices (CCD) are investigated by using MOS capacitors for enhancing their ionizing radiation tolerance. Authors have found that the gate oxidation temperature, thickness of SiO_2 gate insulator and high temperature processes after gate oxidation are crucial for determining the radiation tolerance of the devices, and proposed to decrease the thickness of gate insulator, perform gate oxidation at 1000 deg C by means of dry oxidation and minimize the number of high temperature procedure steps after gate oxidation. All stated above is a necessary preparation for priducing radiation hardened charge-coupled devices.

367

Ionizing Radiation and Life  

British Library Electronic Table of Contents (United Kingdom)

Abstract Ionizing radiation is a ubiquitous feature of the Cosmos, from exogenous cosmic rays (CR) to the intrinsic mineral radioactivity of a habitable world, and its influences on the emergence and persistence of life are wide-ranging and profound. Much attention has already been focused on the deleterious effects of ionizing radiation on organisms and the complex molecules of life, but ionizing radiation also performs many crucial functions in the generation of habitable planetary environments and the origins of life. This review surveys the role of CR and mineral radioactivity in star formation, generation of biogenic elements, and the synthesis of organic molecules and driving of prebiotic chemistry. Another major theme is the multiple layers of shielding of planetary surfaces from th...

2011-01-01

368

Intraband Absorptoin of Far-Infrared Light by Electrons in ...  

Science.gov (United States)

... significant change of spontaneous radiation intensity. It is very sensitive technique allowing the observation of small changes of light absorption. ...

1999-06-18

369

International trends in radiation protection  

International Nuclear Information System (INIS)

The great uranium debate throughout the industrialised world has intensified awareness of the biological hazards from ionizing radiation. It is therefore appropriate to use this awareness to draw attention to medical X-Radiation which today represents the most significant risk to future generations. There is ample legislation to control proliferation of nuclear development but in diagnostic radiology proliferation is unlimited; most international surveys indicate an unchecked annual growth rate of 15%. The article looks at risk hypotheses, dose measurements and the responsibilities of practising radiographers, and also reviews the international situation as reported at the 1977 world congress of radiation protection.

370

INTERACTIONS OF COHERENT OPTICAL RADIATION WITH ...  

Science.gov (United States)

... and flashtube. Unfortunately, we had insufficient laser intensity to use the harmonic from a KDP crystal as a monitor. This ...

1964-08-31

371

Helium atom doping of molybdenum and its influence on the radiation hardenings  

International Nuclear Information System (INIS)

Experimental results on study of helium concentration influence on degree of molybdenum radiation hardening for various method of cyclotron doping differing in degree and damage character are presented. It is established that accumulation of helium atoms in molybdenum for simultaneous formation of radiation defects caused by low energetic primary-knocked atoms leads to higher degree of hardening than for high energetic ion irradiation. It is shown that with increase of helium atom concentration the degree of radiation hardening for the same level of damage increases. 4 refs.; 3 figs. (author).

1990-05-22

372

Growth, Characterization and Device Development in ...  

Science.gov (United States)

... eV. In some instances the spontaneous radiation from a free electron laser system was employed to obtain images. The ...

1998-03-01

373

Gravitational waves from the big bang  

Energy Technology Data Exchange (ETDEWEB)

The gravitational radiation produced by the big bang is calculated in order to provide a condition for the unification of the gravitational and electromagnetic forces. By analogy with electromagnetic radiation and under the assumption that gravity is also quantized, it is shown that matter would have decoupled from gravitational radiation at a time of approximately 10 to the -43rd sec and would have dominated it at 10 to the -17th sec. Furthermore, the theory predicts a background gravitational radiation temperature of 0.003 K which peaks at a wavelength of about 1 m, which may be detected by the comparison of the synchronization of clocks at increasing distances.

1980-12-20

374

Free electron radiation and the Beijing Free Electron Laser  

International Nuclear Information System (INIS)

Various particle-photon or beam-wave interactions are discussed. To be of use as intense radiation sources, it is necessary that these interactions produce coherent radiation. The free electron laser (FEL), developed on the basis of undulator radiation, is the result of many years of interaction between physics and technology. It has many features, such as continuous tunability over a wide wavelength range, excellent optical quality, high power and short pulse capability, and thus has many potential applications. FEL development in China and abroad are mentioned and the Beijing FEL presented to illustrate the physics and technology involved in an FEL project.

375

Estimation of X-rays dose in the crystals of final thickness  

International Nuclear Information System (INIS)

A calculation method of the X-ray radiation dose (energy of gamma- radiation remains in the range of energies where the mechanism of photoelectric absorption is the prevailing one) absorbed in the absorbers of final thickness is suggested. Calculations of resorption of secondary radiation (characteristic fluorescences) in the substance and kinetic energy of photoelectrons caused by this resorption (it would be enough to consider one or two hard series) are presented. Calculation of the spectrum of photoelectron energy yield in TeInSe_2 monocrystal for 0.1-0.5 A range of X-ray radiation is conducted by the developed methods.

376

Emission of photons by electrons and positrons passing through a thin single crystal  

Energy Technology Data Exchange (ETDEWEB)

We consider the radiation of particles (electrons and positrons) undergoing planar channeling in a single crystal of small thickness L. We show that for Lapprox...pi..b/theta/sub L/, where b is the lattice constant and theta/sub L/ is the Lindhard angle, in addition to the principal maxima of spontaneous radiation of channeled particles in the spectrum there are additional interference maxima, and the positions of all maxima of the radiation intensity depend on L. We discuss the dependence of the intensity of radiation at various frequencies on the crystal thickness.

1984-07-01

378

Electroluminescence Study of Green Be-Contained II-VI ...  

Science.gov (United States)

... laser structure. However, still the greater part (60%) of emitted photons is a result of a spontaneous radiation process. In ...

2000-06-23

379

Effect of Radiation Exposure on the Retention of Commercial NAND Flash Memory  

Science.gov (United States)

We have compared the data retention of irradiated commercial NAND flash memories with that of

2011-01-01

380

Distributed-processing radiation management system for nuclear power plants  

Energy Technology Data Exchange (ETDEWEB)

The importance of radiation management for nuclear facilities including nuclear power plants has increased as the general public understanding has progressed, and necessary information for management must be processed exactly and quickly. In nuclear power plants, radiation management is performed by each individual operation, and collected information is managed by the system of each operation. The distributed-processing radiation management system has been developed aiming to use a general-purpose LAN and make quick and efficient use of information managed by individual operations. This paper describes the system configuration and functions. (author)

1999-06-01

381

Difference in the effects produced by non-radioactive and radioactive calcium  

International Nuclear Information System (INIS)

... aluminum calcium calcium 45 cations citric acid corrosion inhibition radiation

382

Application of low dose radiation for preservation of sea foods  

International Nuclear Information System (INIS)

Treatment of food with low doses of gamma radiation has been recognized to have two main advantages. These consist of: (1) improvement of food safety by elimination of pathogens and (2) reduction of microbial spoilage and extension of shelf life of perishable items by reducing the number of viable spoilage organisms. Studies during the last few decades have conclusively proved the beneficial effects of radiation with respect to fishery products. The three potential areas of application to fish products include: (i) radurization for shelf life extension (ii) radicidation to eliminate food borne pathogens in the products and (iii) radiation treatment to dried products to control insects.

1994-03-01

383

Accelerated aging tests for radiation degradation of organic materials  

International Nuclear Information System (INIS)

(Jun 1984). United States Clough, RL Gillen, KT Sandia Nat'l Laboratories

1984-06-03

388

222Rn exhalation rate from Egyptian building materials using active and passive methods  

International Nuclear Information System (INIS)

... Sciences, Research Center for Radiation Protection, Chiba (Japan) Hafez,

2009-03-01

389

#beta#-delayed proton decays of "8"1Zr and "8"5Mo  

International Nuclear Information System (INIS)

... RADIATION PHYSICS beta decay delayed protons excited states experimental

390

"2"0"3Pb yields while irradiating thallium with protons and deuterons  

International Nuclear Information System (INIS)

... data deuteron beams energy dependence errors gamma radiation lead 203

391

Variations in humanized and defined culture conditions supporting derivation of new human embryonic stem cell lines  

DEFF Research Database (Denmark)

The evolution of "humanized" (i.e., free of animal sourced reagents) and ultimately chemically defined culture systems for human embryo stem cell (hESC) isolation and culture is of importance to improving their efficacy and safety in research and therapeutic applications. This can be achieved by integration of a multitude of individual approaches to replace or eliminate specific animal sourced reagents into a single comprehensive protocol. In the present study our objective was to integrate strategies obviating reliance on some of the most poorly defined and path-critical factors associated with hESC derivation, namely the use of animal immune compliment to isolate embryo inner cell mass, and animal sourced serum products and feeder cells to sustain hESC growth and attachment. As a result we report the derivation of six new hESC lines isolated by outgrowth from whole blastocysts on an extracellular matrix substrate of purified human laminin (Ln) with transitional reliance on ...

2006-01-01

392

Use of gamma irradiation for microbial inactivation of buckwheat flour and buckwheat food products, 6  

International Nuclear Information System (INIS)

The effects of gamma irradiation at 0.2#approx#0.4 Mrad and condition for processing of buckwheat noodles on sensory quality and physical properties were investigated. The results were as follows: (1) Sensory evaluation of buckwheat noodles, prepared with the 70 % ratio of buckwheat flour, was decreased according to an increase of irradiation dose of buckwheat flour. Hardness and adhesiveness of buckwheat noodles caused by irradiation should be given large effect to the texture. Elasticity of buckwheat noodles was linearly decreased with increasing of irradiation dose of buckwheat flour, and elasticity of buckwheat noodles was decreased about 15 % by an increase of irradiation dose at 0.3 Mrad. (2) Maximum torque in Farinograph test was linearly decreased with increasing of irradiation dose of buckwheat flour, and maximum torque was decreased about 3 % by increasing of irradiation dose with 0.1 Mrad. (3) Sensory evaluation was also decreased by increasing content of irradiated buck ...

1989-01-01

393

Two and 8-azido photoaffinity probes. 2. Studies on the binding process of 2-5A synthetase by photosensitive ATP analogues  

International Nuclear Information System (INIS)

The photoaffinity probes [#gamma#-"3"2P]2-azidoATP (2-N_3ATP) and [#alpha#-"3"2P]8-azido-ATP (8-N_3ATP) were used to investigate the binding of ATP to highly purified 2-5A synthetase. 2-N_3APT and 8-N_3ATP are substrates for 2-5A synthetase. In this study the authors show that 2- and 8-N_3ATP are competitive inhibitors of the enzymatic conversion of ATP to 2-5A. Ultraviolet irradiation results in the photoinsertion of 2-N_3ATP and 8-N_3ATP into the enzyme. The covalent photoinsertion of [#alpha#-"3"2P]8-N_3ATP into the 2-5A synthetase is proportional to the inactivation of the enzyme as UV irradiation is increased. Photolabeling of 2-5A synthetase is saturated at 1.5 mM 2-N_3ATP and 2.0 mM 8-N_3ATP. Computer analysis of the curvilinear Scatchard plots of the 2-5A synthetase suggest the presence of high-affinity and low-affinity binding sites that may correspond to the acceptor and the 2'-adenylation sites of the enzyme. The competition of nucleotides for the ...

394

Involvement of a glutamergic mechanism in gamma-dendrotoxin-induced hippocampal neuronal cell loss in the rat.  

Science.gov (United States)

The epileptogenic and neurodegenerative effects of gamma-dendrotoxin, from Dendroaspis angusticeps, a specific blocker of a non-inactivating, voltage-sensitive K+ channel, were studied after focal injection into one dorsal hippocampus in rats pretreated with CGP040116, a N-methyl-D-aspartate (NMDA) receptor antagonist, and in rats bearing a monolateral surgical lesion of the Schaffer collaterals whose terminals originate from CA3 pyramids and release glutamate in the CA1 hippocampal area. Administration of 35 pmol gamma-dendrotoxin elicited in all of the treated animals (n=8) bilateral EEG discharges and damage to the hippocampal formation. Quantitation of the damage revealed significant bilateral neuronal cell loss in the CA1, CA3 and CA4 pyramidal cell layers. The lowest dose (0.35 pmol; n=4) of the toxin used did not affect EEG activity and failed to cause significant hippocampal cell loss whereas the 3.5 pmol (n=6) dose caused EEG seizures and hippocampal cell ...

2004-03-01

395

Inhibitor of DNA synthesis is present in normal chicken serum  

Energy Technology Data Exchange (ETDEWEB)

The authors have found that heat-inactivated serum (57/sup 0/C for 1 hour) from normal chickens reduces the proliferation of mitogen-stimulated chicken and murine splenocytes as well as some transformed mammalian lymphoblastoid cell lines. Greater than a 50% reduction in /sup 3/H-thymidine incorporation was observed when concanavalin A (Con A)-activated chicken splenocytes that were cultured in the presence of 10% autologous or heterologous serum were compared to mitogen-stimulated cells cultured in the absence of serum. Normal chicken serum (10%) also caused greater than 95% suppression of /sup 3/H-thymidine incorporation by bovine (EBL-1 and BL-3) and gibbon ape (MLA 144) transformed lymphoblastoid cell lines. The only cell line tested that was not inhibited by chicken serum was an IL-2-dependent, murine cell line. Chicken serum also inhibited both /sup 3/H-thymidine incorporation and IL-2 synthesis by Con A-activated murine splenocytes. Suppression was caused by ...

1986-03-05

396

Identification of a nucleoside triphosphate binding site on calf thymus RNA polymerase II  

Energy Technology Data Exchange (ETDEWEB)

A nucleoside triphosphate binding site on calf thymus RNA polymerase II was identified by using photoaffinity analogues of adenosine 5'-triphosphate and guanosine 5'-triphosphate. Both radiolabeled 8-azidoadenosine 5'-triphosphate (8-N3ATP) and radiolabeled 8-azidoguanosine 5'-triphosphate (8-N3GTP) bound to a single polypeptide of this enzyme. This polypeptide has a molecular mass of 37 kilodaltons and an isoelectric point of 5.4. Ultraviolet (UV) irradiation was necessary for photolabeling to occur. In addition, no labeling occurred when the probe was prephotolyzed or when the enzyme was inactivated. Furthermore, photolabeling of the enzyme could be decreased by preincubation with natural substrates. To provide evidence that the radiolabeled polypeptide forms a part of the domain of the nucleoside triphosphate binding site, experiments were performed using unlabeled 8-N3ATP. Although this unlabeled analogue was not a substrate ...

1986-01-14

397

Genetic control of immune response to pseudorabies and atrophic rhinitis vaccines: II. Comparison of additive direct and maternal genetic effects.  

Science.gov (United States)

Data from 52 litters farrowed in two seasons of a cross-fostering experiment were analyzed to estimate variances and covariances for additive direct and maternal genetic effects on immune response to pseudorabies virus and B. bronchiseptica vaccine. Twenty purebred boars and 44 sows of the Duroc, Landrace and Yorkshire breeds were used. Immune response was measured after vaccine challenge. A modified-live pseudorabies (PR) vaccine was administered to piglets at 28 d of age; response was measured by log2 serum neutralization titers at 56 d. An inactivated B. bronchiseptica bacterin was administered at 28, 42 and 112 d. Antibody levels were measured relative to positive and negative controls at 28, 56 and 119 d by using an enzyme-linked immunosorbent assay (ELISA). Results from this study for heritability were .18 +/- .09 for PR titer and .15 +/- .07 and .52 +/- .15 for 56- and 119-d ELISA values, respectively. The variability due to nurse environment (maternal ...

1987-02-01

398

Enhancement of starch conversion efficiency with free and immobilized pullulanase and alpha-1,4-glucosidase.  

Science.gov (United States)

Glucoamylase and pullulanase were immobilized on reconstituted bovine-hide collagen membranes using the covalent azide linkage method. A pretanning step was incorporated into the immobilization procedure to enable the support matrix to resist proteolytic activity while accommodating an operating temperature of 50 degrees C. The immobilized glucoamylase and pullulanase activities were 0.91 and 0.022 mg dextrose equivalent (DE) min(-1) cm(-2) of membrane, respectively. Immobilized glucoamylase had a half-life of 50 days while the immobilized pullulanase had a half-life of 7 days. This is a considerably improved stability over that reported by other researchers. The enzymes were studied in their free and immobilized forms on a variety of starch substrates including waxy maize, a material which contains 80% alpha-1-6-glucosidic linkages. Substrate concentrations ranged from 1% to a typical commercial concentration of 30%. Conversion efficiencies of 90-92% DE were obtained with free and ...

1982-02-01

399

Does tea tree oil have a place in the topical treatment of burns?  

Science.gov (United States)

Burnaid is a sorbalene-based cream containing 40 mg/g of tea tree oil and 1 mg/g of triclosan. This investigation was carried out to determine the effect of Burnaid, a commercial tea tree oil preparation, against Enterococcus faecalis (ATCC29212), Staphylococcus aureus (ATCC29213), Escherichia coli (ATCC25922), and Pseudomonas aeruginosa (ATCC27853), with the activity of the base product in the commercial preparation. The organisms were suspended in sterile saline (0.5 McFarland Standard) and inoculated onto horse blood agar (E. faecalis and S. aureus) or Mueller-Hinton agar (E. coli and P. aeruginosa). One hundred microliters of Burnaid unsterilized, Burnaid sterilized and the base product (Tinasolve) were placed in duplicate in wells cut into the agar plates. Sterility and inactivation cultures were also performed on the samples. None of the samples were found to be contaminated with bacteria prior to testing. Only S. aureus and E. coli showed zones of growth ...

1997-06-01

400

Biosorption of Cd(II), Ni(II) and Pb(II) from aqueous solution by dried biomass of aspergillus niger: application of response surface methodology to the optimization of process parameters  

Energy Technology Data Exchange (ETDEWEB)

In this study, the biosorption of Cd(II), Ni(II) and Pb(II) on Aspergillus niger in a batch system was investigated, and optimal condition determined by means of central composite design (CCD) under response surface methodology (RSM). Biomass inactivated by heat and pretreated by alkali solution was used in the determination of optimal conditions. The effect of initial solution pH, biomass dose and initial ion concentration on the removal efficiency of metal ions by A. niger was optimized using a design of experiment (DOE) method. Experimental results indicated that the optimal conditions for biosorption were 5.22 g/L, 89.93 mg/L and 6.01 for biomass dose, initial ion concentration and solution pH, respectively. Enhancement of metal biosorption capacity of the dried biomass by pretreatment with sodium hydroxide was observed. Maximal removal efficiencies for Cd(II), Ni(III) and Pb(II) ions of 98, 80 and 99% were achieved, respectively. The biosorption capacity of A. ...

2009-10-15

401

B chain is a functional subunit of beta-bungarotoxin for inducing apoptotic death of human neuroblastoma SK-N-SH cells.  

Science.gov (United States)

beta-Bungarotoxin (beta-Bgt), a presynaptic phospholipase A(2) (PLA(2)) neurotoxin isolated from the venom of Bungarus multicinctus, consists of A chain and B chain. The goal of the present study is to explore the functional contribution of the two subunits to the toxicity of beta-Bgt. beta-Bgt was found to induce apoptotic death of SK-N-SH cells via elevating intracellular Ca(2+) and intracellular ROS production. Moreover, an activation of p38 MAPK was associated with the cytotoxicity of beta-Bgt. SB202190 (p38 MAPK inhibitor), N-acetylcysteine (antioxidant reagent), 1,2-bis(2-aminophenoxy)ethane-N,N,N,N-tetraacetic acid (BAPTA) (Ca(2+) chelator) and the inhibitors of Ca(2+) release from intracellular depots (ruthenium red and 2-aminoethoxydiphenyl borate) effectively attenuated the cytotoxicity of beta-Bgt. In sharp contrast to the inability of A chain, B chain was able to induce cytotoxic effects on SK-N-SH cells as beta-Bgt did. Abolishment of PLA(2) activity did not significantly ...

2007-10-13

402

Appendix W: deep sea biophysics (microbiology and amphiped studies)  

International Nuclear Information System (INIS)

CNPT-3 is the laboratory designation of a strain of bacteria that reproduces best at deep-sea pressures. It was isolated from a sample collected at a 5800 m depth of the Pacific Ocean. This isolation was achieved from a sample that had been retrieved without warning. This year we demonstrated that there are similarly behaving bacteria that can be isolated from samples even when retrieved with decompression. The purpose of this project was to define the temperatures and pressures over which CNPT-3 can exist and function. (1) At 2"0C CNPT-3 is eurybathic from about 1000 to 6500 m, as judged from an only slightly pressure dependent generation time. (2) CNPT-3 is unquestionably barophilic at 2"0C, with doubling times of 9 hours at 580 bars and over 18 hours at 1 bar. (3) At 10"0C, reproduction is adversely affected at 1 bar to the extent that CNPT-3 becomes obligately barophilic at 10"0C. Yet reproduction is enhanced above 280 bars and occurs with a regeneration time of 4 hours at 690 bars ...

1981-04-01

403

X-ray generation by the Smith-Purcell effect  

International Nuclear Information System (INIS)

Smith-Purcell (S-P) radiation is produced when electrons graze the surface of a grating. Calculations based on the theory of diffraction radiation show that, given severe restrictions on e"--beam quality, S-P radiation is highly efficient. Efficient S-P x-ray generation requires relativistic e"- beams having a transverse momentum and dimension whose product approaches the Heisenberg uncertainty limit.

404

Transverse velocity modulator and generator schemes based on non-collinear radiation and electron beams  

International Nuclear Information System (INIS)

New non-collinear schemes are suggested for transverse velocity modulation of electron beams and for the generation of coherent spontaneous radiation by these transversely modulated beams. It is shown that due to the non-collinearity some orders of magnitude enhancement can be achieved for the coherent spontaneous radiation (CSR) power at both the fundamental and harmonic frequencies.

2000-05-01

405

The development and testing of emissivity enhancement coatings for thermophotovoltaic (TPV) radiator applications  

Energy Technology Data Exchange (ETDEWEB)

One requirement of a thermophotovoltaic (TPV) radiator is to efficiently emit photons at high temperatures to TPV cells for conversion to electric power. Because many candidate radiator materials with adequate structural properties display low emissivity, coatings or other surface modifications are required for enhancement of emissivity. Six plasma sprayed coatings and one textured surface demonstrated adequate thermal stability and emittance values of 0.8 or greater. Promising attributes of modified surfaces are identified.

1999-03-01

406

The chemistry of UV and BE radiation curing  

International Nuclear Information System (INIS)

The application of photopolymerisation (UV) and electron beams (EB) technologies in radiation rapid cure (PRC) processing is discussed. The chemistry associated with such reactions and the mechanisms of the processes are treated. The occurrence of concurrent grafting to substrate with radiation curing of films is shown to be an advantage in enhancing the properties of certain finished products. The parameters influencing the optimum grafting yield in such PRC processes are discussed. In many applications, the chemistry of such processes combined with the machine, specially for EB is shown. (author).

1987-09-19

407

Spontaneous radiation-induced alignment of dipole moments of atoms moving in a medium  

International Nuclear Information System (INIS)

The effect on an oscillator moving in a medium produced by that part of the radiative force which does not perform work but creates and angular moment is considered. It is shown that the radiative torque turns the dipole toward the axis along which it is moving. Near the axis of motion the dipole executes small oscilltions. The frequency of the oscillations is determined. This effect leads to spontaneous alignment of the dipole moments on moving through the medium. The feasibility of observing the effect experimentally is discussed.

1986-01-01

408

Spontaneous radiation emission during penetration of ions in solids  

International Nuclear Information System (INIS)

In this work, the principal continuum radiative emission processes, which occur during the penetration of ions in solids or gases, are resumed. The characteristics of the following processes are discussed: secondary electron bremsstrahlung (SEB), atomic bremsstrahlung (AB), and internuclear bremsstrahlung (INB). Recent advances of the ion channeling effects in crystal solids on the spontaneous radiative spectra are exposed. (A.C.A.S.).

1988-09-25

409

Solar unit  

Energy Technology Data Exchange (ETDEWEB)

A solar unit is described which contains a cavity radiation receiver, parabolic-cylindrical concentrator, and reflector arranged between the radiation receiver and the concentrator symmetrically in relation to the optical plane of the latter. In order to expand the range of use, it contains a pair of flat mirrors with 2 working surfaces installed at an angle and symmetrically to the optical plane of the parabolic cylindrical concentrator between them and the reflector, while the latter is made in the form of 2 flat mirrors installed at an angle on the cavity radiation receiver.

1982-01-01

410

Solar flux distribution in cavity receivers with parabolic dish collector  

Energy Technology Data Exchange (ETDEWEB)

Thermal absorption with its combined thermal and mechanical loads in a solar receiver does depend significantly on the distribution of incident solar radiation. For a cavity receiver with paraboloid collectar a method is derived which enables the calculation of solar radiation distribution on the areas inside the receiver. The theoretical bases are presented first, and a subsequent example shows the influence of the most important geometric parameters on the distribution of solar radiation.

1982-01-01

411

Radioanalytical chemistry. Vol. 2  

International Nuclear Information System (INIS)

This volume of the monograph covers the following topics: activation analysis, non-activation interaction analysis (elastic scattering of charged particles, absorption and backscattering of beta radiation and photons, radionuclide X-ray fluorescence analysis, thermalization, scattering and absorption of neutrons, use of ionization caused by nuclear radiation, use of ionization by alpha or beta radiation for the measurement of pressure, density and flow rate of gases), and automation in radioanalytical chemistry. (P.A.).

1989-01-01

412

Radiation hazards from medical applications  

International Nuclear Information System (INIS)

An introduction is presented on the radiation hazards connected with biomedical radiography and nuclear medicine. The frequency of radiodiagnostic efforts was rather high in the Netherlands. This was reduced considerably by abolishing the thorax screening of the population. About diagnostic nuclear medicine less can be said because far fewer numerical data are available. An exposition of genetically and somatically significant doses and how to compute them is given. The drawing up of a profit versus risk evaluation for medical applications of ionizing radiations is recommended. (Auth.).

1980-05-31

413

Radiation hardening of optical fiber links by photobleaching with light of shorter wavelength  

International Nuclear Information System (INIS)

The influence of additionally injected short-wavelength photobleaching light on the radiation hardness of Ge-doped graded index fibers working at 1,300 nm wavelength is investigated. Predictions are complicated by the fact that more efficient shortwave bleaching light experiences higher radiation-induced loss. Promising results are found for low fiber temperatures (approx-lt -50 C) and bleaching light of about 835 nm wavelength.

1995-09-18

414

Radiation doses in adults and children in standardized diagnostic radiology  

International Nuclear Information System (INIS)

For comparison of radiation exposure and risk in different diagnostic procedures for adults and children dose measurements and calculations of organs with special risk were carried out. Parameters of image formation influencing image quality as well as of exposure concerning infants and children are recorded and discussed as to radiation exposure and protection. Conclusions are drawn with respect to systems of image formation and to standards of examination and quality assurance.

1987-01-01

415

Radiation doses and somatic risk to patients during cardiac radiological procedures  

International Nuclear Information System (INIS)

The radiation dose to a series of adult and paediatric patients undergoing cardiac catheterisations and adults having percutaneous transluminal coronary angioplasty has been measured/determined directly using lithium fluoride thermoluminescent dosemeters and indirectly using an air ionisation chamber which indicated exposure-area product. Somatic and genetic risks are estimated from the dosimetry results. It is suggested that the magnitude of the radiation hazard is negligible compared with other clinical hazards associated with these procedures. (author).

1986-01-01

416

Radiation accidents with multi-organ failure in the United States.  

Science.gov (United States)

Only a small number of radiation accidents in the United States have been severe enough to result in multi-organ failure (MOF). Medical details of selected medical misadministration and criticality cases are reviewed, with an emphasis on pathophysiology. The four criticality cases are particularly relevant for analysis of MOF, since medical treatment was supportive and did not appreciably alter the clinical evolution of radiation injury. PMID:15975871

2005-01-01

417

Quality assurance in radiotherapy: Proposal of guidelines concerning clinical and technological aspects; Assicurazione di qualita` in radioterapia: Proposta di linee guida in relazione agli aspetti clinici e tecnologici  

Energy Technology Data Exchange (ETDEWEB)

The document, based on European guidelines, was jointly developed by radiation oncologists, radiation physicists and radiation technologists. It contains the aims of the guidelines, professional profiles, roles and responsibilities, personnel and equipment requirements, procedures.

1996-12-01

418

Performance of the transition radiation detector in D{Phi}  

Energy Technology Data Exchange (ETDEWEB)

The transition radiation detector (TRD) for the D{Phi} experiment is currently in operation at Fermilab. Transition radiation production, which has been clearly observed in the collider data, makes the TRD a valuable tool to discriminate electrons and hadrons. We describe an algorithm based on the truncated energy, and illustrate its use for top signal and background. (authors). 7 refs., 6 figs., 2 tabs.

1994-12-31

419

On the effect of ionizing radiation on some factors of hamster natural immunity in norm and in himenolepis diminuta invasion  

International Nuclear Information System (INIS)

Effect of single and chronic irradiation on factors of hamsters natural immunity such as complement, lysozyme and antibodies in norm and in the cestode invasion has been investigated. Significant phase changes in the complement activity level, lysozyme content and specific antibodies tite have been shown to occur in hamster blood under the influence of ionizing radiation. Cestode invasion in irradiated host organism increases the negative effect of ionizing radiation on the hamster immyne system.

1994-01-01

420

Nuclear Raman processes and the development of gamma-ray lasers  

International Nuclear Information System (INIS)

This review briefly describes current efforts to develop superradiant sources of coherent radiation for the sub-nanometer range of wavelenghs, using nuclear rather than the atomic or molecular transitions that are stimulated in existing lasers. First the radiative (including Raman) interactions of nuclei with those of atoms and molecules are compared; then the present status of research on the fundamental problems involved in stimulating nuclear gamma radiation is described. (author). 20 refs.; 2 figs.

421

Near-Core and In-Core Neutron Radiation Monitors for Real Time Neutron Flux Monitoring and Reactor Power Level Measurements  

Energy Technology Data Exchange (ETDEWEB)

MPFDs are a new class of detectors that utilize properties from existing radiation detector designs. A majority of these characteristics come from fission chamber designs. These include radiation hardness, gamma-ray background insensitivity, and large signal output.

2006-06-12

422

Modalidade de morte em mamiferos expostos a irradiacao de corpo inteiro (sindrome aguda da radiacao). (Modes of death in mammals exposed to whole body radiation (acute radiation syndromes)).  

Science.gov (United States)

When an animal is exposed to a sufficient amount of radiation, there will be changes in many organs of the body, and as a result of either the effects in one particular organ or the interaction of effects in several organs, the animal as a whole will show...

1990-01-01

423

Ionising radiation. Part 2  

Energy Technology Data Exchange (ETDEWEB)

A brief tutorial on the health effects of ionising radiation is presented. The distinction between somatic and genetic health effects is explained. The two types of somatic health effects, i.e., acute and chronic effects, are discussed, as well as the concepts of ''deterministic'' and ''stochastic'' (also called ''probabilistic'') health effects. The possibility of cancer caused by DNA damage is discussed. The document ends with the definition of some key radiation terms.

2000-11-01

424

Investigation of radiation effects of interaction of #beta#"- -radiation with polyvinylchloride  

International Nuclear Information System (INIS)

Dissipation of energy of #beta#"--radiation in polyvinylchloride (PVC) was analyzed. Change of PVC properties at irradiation by beta beams with energy 2,32 MeV was characterized using potentials of inter- and intramolecular interactions as well as Born potential. Correlation between some micro- and macroproperties of PVC was detected and ways of their controlled correction were proposed. (authors)

425

Investigation of radiation defects in solids using the EXAFS method  

International Nuclear Information System (INIS)

The exafs method is proposed as a more informative, universal one to investigate the radiation defects in solids. The successful results as obtained by the author using the synchrotron radiation source are reported for the first time. The measurements were carried out in GaAsP crystals irradiated with 50 MeV electrons.

1978-02-15

426

Health hazards to children due to the Chernobyl accident?  

International Nuclear Information System (INIS)

The article tries to assess the radiation effects as objectively as possible. In conclusion, some steps that should be taken in future are listed, as e.g.: continuous monitoring of the radioactivity levels in air and soil, and recording of data for complete information. Further, investigation and assessment of radiation exposure of children, especially in regions most heavily affected; radioactivity monitoring of the food and milk given to children, and scientific research into the problem by pediatrists, and determination of maximum acceptable radiation doses. (orig./HSCH).

427

Guarantee outline of radiation hardening for satellite  

International Nuclear Information System (INIS)

The Guarantee Outline presents the technical demands of design and contents of assessment for radiation hardening in satellite engineering in China. It includes the basis of design in space environment of polar orbit, the contents of design for general radiation hardening, the requirements and assessments of the single-board computer, the requirements of design for circuits (including hardware and software), the choices and assessments for devices, and the primary stipulations for the requirements of design and assessments against the phenomenon of charge and discharge.

428

Experience in implementing the idea of work management in radiation practices in Daya Bay NPP  

International Nuclear Information System (INIS)

The philosophy of work management in radiation protection puts emphasis on the following up and management of overall process from work selection, planning, preparation, implementation till experience feedback, and overall optimization of production and safety management. This paper reports practices and experiences of Daya Bay nuclear power plant in the implementation of the philosophy during operational radiation protection through the practical examples

2004-05-01

429

Evaluation of radiation resistance of cable connector material  

Energy Technology Data Exchange (ETDEWEB)

Radiation degradation of polycarbonate (PC) and polybutylene terephthalate (PBT) used as cable connector was evaluated using DSC, TGA, and mechanical properties. Glass transition temperature, melting temperature, 5% weight loss temperature, elongation at break, and tensile strength measurements were carried out for each of {gamma}-ray irradiated samples. In the results of those analyses, PC has radiation resistance better than PBT as a cable connector material.

2002-10-01

430

Developments and potential of radiation processing in the Philippines  

Energy Technology Data Exchange (ETDEWEB)

This paper describes the research and development activities in three areas of radiation processing, namely: food irradiation, medical product sterilization and wood plastic combination. Plans and efforts exerted to acquire a larger gamma source to augment our present 5,000 curie source are discussed. Cost estimates for a radiation facility are presented on the basis of the market potential of food irradiation and medical product sterilization. Existing local industries that can benefit from the adaptation of irradiation technology in their processing requirements are described.

1981-01-01

431

Decree of the Ministry of Health about conditions of irradiation of food, permissible additional substances or other food components, which can be subjected to ionizing radiation action, their specification, maximum irradiation doses as well as about requirements for marking and introducing into turnover  

International Nuclear Information System (INIS)

The decree refers to conditions of irradiation of food and its components for radappertization and radurization using gamma radiation from cobalt 60 or cesium 137, X radiation or electron beam up to maximum total medium absorbed dose 10 kGy.

2003-03-04

432

CRC handbook of laser science and technology. Volume 3. Optical materials, Part 1 - Nonlinear optical properties/radiation damage  

Energy Technology Data Exchange (ETDEWEB)

This book examines the nonlinear optical properties of laser materials. The physical radiation effects on laser materials are also considered. Topics considered include: nonlinear optical properties; nonlinear and harmonic generation materials; two-photon absorption; nonlinear refractive index; stimulated Raman scattering; radiation damage; crystals; and glasses.

1986-01-01

433

Automated analysis of damages for radiation in plastics surfaces; Analisis automatizado de danos por radiacion en superficies plasticas  

Energy Technology Data Exchange (ETDEWEB)

Analysis of damages done by the radiation in a polymer characterized by optic properties of polished surfaces, of uniformity and chemical resistance that the acrylic; resistant until the 150 centigrade grades of temperature, and with an approximate weight of half of the glass. An objective of this work is the development of a method that analyze in automated form the superficial damages induced by radiation in plastic materials means an images analyst. (Author)

1990-02-15

434

Assessment of the efficacy of braking radiation beam formation of electron accelerators  

International Nuclear Information System (INIS)

Proceeding from analysis of the influence of parameters of the target-filter system on radiation-physical characteristics of braking radiation, some recommendations were issued for assessment of the forming systems of medical accelerators of electrons. A new criterion - a coefficient of the forming system efficacy - was introduced, characterizing a beam formation tract with relation to a whole set of radiotherapeutic problems.

435

Apoptosis induced by high- and low-LET radiations  

International Nuclear Information System (INIS)

Cell death after irradiation occurs by apoptosis in certain cell populations in tissues. The phenomenon also occurs after high linear energy transfer (LET) irradiation, and the relative biological effectiveness (RBE) is 3 to 4 (with respect to low-LET radiation and apoptosis in intestinal crypts) for neutrons with energies of 14 MeV and up to 600 MeV. It is thought that p53 plays a role in the phenomenon, as radiation-induced apoptosis is not observed in p53-null animals. (orig.).

436

X-ray imaging dose due to the digital imaging devices used in radiation therapy for patient positioning and repositioning: How to take it into account?; Les doses dues a l'imagerie numerique pour le controle de positionnement du patient en radiotherapie: comment les prendre en compte?  

Energy Technology Data Exchange (ETDEWEB)

The patient positioning and repositioning control in radiation therapy all along the treatment can be conducted using a variety of X-ray sources and imaging detector devices. The development of image guided radiation therapy techniques leads to more frequent use of this imaging control. In this article we summarize the current methods for measuring the dose delivered by X-ray imaging devices used in radiation therapy, as well as basic proposals to take account of these imaging doses for prescribing, recording and reporting radiation therapy treatment. (authors)

2008-12-15

437

Worker radiation doses in the United States at the dawn of the atomic era (1940--1960)  

Energy Technology Data Exchange (ETDEWEB)

Radiation doses to workers at the Manhattan Engineer District (MED) and US Atomic Energy Commission (AEC) sites due to external irradiation during 1940--1960 are reviewed. Categorized radiation dose data were available from AEC annual reports for some years. Annual individual radiation dose data for ten MED/AEC sites for all years were available from the US Department of Energy`s (DOE) Comprehensive Epidemiologic Data Resource (CEDR). These data are combined to produce an estimate of external collective dose equivalent to 172,000 person-rems (1720 person-Sv) for 1940--1960. During this period there were 41 overexposures, 19 criticality incidents, and 3 deaths due to acute radiation syndrome among several hundred thousand workers.

1994-06-01

438

Transverse Coherence Properties of the LCLS X-Ray Beam  

Science.gov (United States)

Self-amplifying spontaneous radiation free-electron lasers, such as the LCLS or the European X-FEL, rely on the incoherent, spontaneous radiation as the seed for the amplifying process. Though this method overcomes the need for an external seed source one drawback is the incoherence of the effective seed signal. The FEL process allows for a natural growth of the coherence because the radiation phase information is spread out within the bunch due to slippage and diffraction of the radiation field. However, at short wavelengths this spreading is not sufficient to achieve complete coherence. In this presentation we report on the results of numerical simulations of the LCLS X-ray FEL. From the obtained radiation field distribution the coherence properties are extracted to help to characterize the FEL as a light source.

2007-04-16

439

The effective per caput dose equivalent as a measure of medical radiation exposure of the population - a complement or an alternative to the genetically significant dose  

International Nuclear Information System (INIS)

The GSD must be considered as a quantity by means of which the risk in a given population can be described exclusively in terms of genetic risk. In cases of a simultaneous increase in the rate of examinations, the GSD may lead to a misinterpretation of the population exposure, suggesting a decreasing trend, although there is an actual increase in the somatic radiation exposure. It is recommended to indicate not only the GSD but also the amount of somatic radiation exposure of the population for each specific source when comparing and evaluating radiation exposures from different sources. Although the somatically significant dose formally would be suited as a complement to the GSD, it is recommended to use the effective per caput dose equivalent. It must be pointed out that the application of the concept of effective dose equivalent is only appropriate for comparative evaluations of the population exposure to different ...

1984-01-01

440

Specific features of radiation damage in titanium alpha-alloys  

International Nuclear Information System (INIS)

Titanium base 'alpha'-alloys (Pt-7M, RK-20 and Ti-5Al-2Zr-1.5V) are considered for their behaviour under neutron irradiation. The role of alloying elements in radiation hardening is discussed depending of neutron fluence and irradiation temperature. For PK-20 alloy three stages of change in mechanical properties are revealed which are following: incubation period and weak hardening, intense radiation hardening, radiation hardening attenuation. Irradiation temperature rise results in an increase of incubation period and threshold neutron fluence. A special attention is paid to hydrogen absorption in #alpha#-titanium alloys under irradiation. It is concluded that titanium base 'alpha'-alloys are serviceable as structural materials in nuclear plants with allowance made for peculiar features of their radiation behaviour. 4 refs.; 7 figs.; 1 tab.

441

Risk assessment for radiation protection purposes  

International Nuclear Information System (INIS)

In defining criteria for good protection against ionizing radiation, it is important to assess quantitatively the likely risk of any radiation exposure. The 'somatic' risks to the individual result mainly from induction of cancer in the organs irradiated, and these risks can now be estimated on the basis of numerous detailed epidemiological surveys of exposed human populations. Estimates of the risk of hereditary effects, from genetic changes induced in germ cells, are based largely on the frequency with which such effects are induced in other species. In both cases the risk at very low dose can be inferred using knowledge of the way in which radiation damage is caused in tissues. Coherent systems of radiation protection are based on a restriction of doses to the whole body and to individual organs, such that the induction of cancer and genetic harm is infrequent, and the threshold dose for causing ...

1980-01-01

442

Radiative properties of a solar cavity receiver/reactor with quartz window  

British Library Electronic Table of Contents (United Kingdom)

An energy transfer and conversion model for high-temperature solar cavity receivers has been developed using the transport behaviour of solar radiation as described by the spectral radiative exchange factors. A Monte-Carlo ray-tracing method coupled with optical properties was adopted, to predict radiation characteristics of the solar collector system by calculating radiative exchange factors. A cavity receiver with a plano-convexo quartz window was proposed, based upon the directional characteristics of the focal flux and the redistribution effect of the quartz window. Parametric studies on the windowed receiver provided a more uniform flux distribution, higher efficiency and lower loss than the windowless receivers. The predicted results serve as a design reference for the solar receiver...

2011-01-01

443

Radiation-induced large intracranial vessel occlusive vasculopathy.  

Science.gov (United States)

Two patients who developed large intracranial vessel occlusion after standard radiation therapy for brain tumor are described. This form of vascular occlusion is usually seen in patients who have previously been treated by radiotherapy for intracranial tumor who then develop a relatively acute change in neurologic status. Histology of the lesion mimics accelerated focal arteriosclerosis. The clinical and radiographic manifestations of one case were highly atypical. The vasculopathy became evident shortly after termination of radiation therapy for a fourth ventricular ependymoma, and the angiographic picture stimulated a diffuse arteritis. The second patient was more typical, with clinical symptoms developing 12 years after radiation therapy for an oligodendroglioma. Occlusion of a proximal vessel that had been included in the radiation port was demonstrated radiographically and confirmed by pathologic ...

1980-01-01

444

Radiation-induced large intracranial vessel occlusive vasculopathy  

Energy Technology Data Exchange (ETDEWEB)

Two patients who developed large intracranial vessel occlusion after standard radiation therapy for brain tumor are described. This form of vascular occlusion is usually seen in patients who have previously been treated by radiotherapy for intracranial tumor who then develop a relatively acute change in neurologic status. Histology of the lesion mimics accelerated focal arteriosclerosis. The clinical and radiographic manifestations of one case were highly atypical. The vasculopathy became evident shortly after termination of radiation therapy for a fourth ventricular ependymoma, and the angiographic picture stimulated a diffuse arteritis. The second patient was more typical, with clinical symptoms developing 12 years after radiation therapy for an oligodendroglioma. Occlusion of a proximal vessel that had been included in the radiation port was demonstrated radiographically and confirmed by pathologic ...

1980-01-01

445

Radiation protection and the role of TSOs in Kenya  

International Nuclear Information System (INIS)

Since the late '60s and through the early '90s Kenya has always recognized and appreciated the need for support from Technical and Scientific Support Organizations (TSOs) for activities geared towards enhancing nuclear and radiation safety. The TSOs have since then gained increasing importance for provision of technical and scientific basis for policy formulation, implementation and legislation with regard to radiation safety. National and specific operator programmes on safety and security of radiation source and radioactive waste recognize and encourage the active participation of TSOs. Due to the role they play, technical competence, transparency and the observance of ethical practices have become essential both for the regulator and the regulated. In this respect, interaction and cooperation between stake holders (regulatory authorities, users of radiation, generators of radioactive waste, ...

2007-08-01

446

Radiation protection  

International Nuclear Information System (INIS)

The book presents a very good account of all aspects of protection from ionizing radiation. The quantities and units are given and defined used in nuclear physics and dosimetry. The effects of ionizing radiation on cells and on man are described. The principles are presented of radiation protection including limits and valid regulations and decrees. Also discussed is internal irradiation and its modelling. A great part of the book is devoted to aspects of monitoring persons, the living and working environment and to the determination of internal contamination. The system of radiation protection in Czechoslovakia is described and some practical questions are discussed of protection during radiodiagnosis and radiotherapy, in the nuclear fuel cycle, in the operation of nuclear power installations and in crack detection. In conclusion a survey is given of the population exposure from various natural and ...

1988-01-01

447

Radiation hardening of integrated circuits technologies  

International Nuclear Information System (INIS)

The radiation hardening studies started in the mid decade 1960-1970. To survive the different military or space radiative environment, a new engineering science was born, to understand the degradation of electronics components. The different solutions to improve the electronic behavior in such environments have been named 'radiation hardening' of the technologies. Improvement of existing technologies, and qualification methods have been widely studied. However, on the other hand, specific technologies were developed: the Silicon On Insulator technologies for CMOS or Bipolar. The HSOI3HD technology offers today the highest hardening level for the integration density of hundreds of thousand transistors on the same silicon. Full complex systems could be produced on a single die with a technological radiation hardening and no more system hardening.

448

Radiation from Relativistic Strongly Magnetized Outflows  

CERN Document Server

Relativistic strongly magnetized winds outflowing from fast-rotating compact objects like millisecond pulsars with surface magnetic fields of $\\sim 10^{15}-10^{16}$ G are plausible sources of cosmological $\\gamma$-ray bursts. In such winds, there are at least three regions where extremely powerful X-ray and $\\gamma$-ray emission may be generated. The first radiating region is the wind photosphere that is at a distance of $\\sim 10^9$ cm from the compact object. The second radiating region is at a distance of $\\sim 10^{13}-10^{14}$ cm. In this region, the striped component of the wind field is transformed into large-amplitude electromagnetic waves. The third radiating region is at a distance of $\\sim 10^{16}-10^{17}$ cm, where deceleration of the wind due to its interaction with an ambient medium becomes important. Radiation from all these regions is considered.

1999-01-01

449

Radiation exposure to patients during hepatic interventional procedure  

International Nuclear Information System (INIS)

Objective: To investigate the X-ray radiation dose patients dealt with the hepatic intervention. Methods: Thermoluminescence and tissue-equivalent anthropomorphic phantom were used to measure the X-ray radiation dose in patients dealt with the hepatic intervention in 85 patients. Results: The peak skin dose in the patients who accepted hepatic intervention was from 179.95 to 1759.00 mGy, effective dose approached 29.22 mSv (male), 29.27 mSv (female). Conclusion: Hepatic intervention is now regarded as an important therapeutic method for liver cancer. However, the patients were exposed to too much X-ray radiation during interventional procedures. Some more effective protection should be taken to decrease the X-ray radiation dose accepted by patients. (authors)

2005-05-01

450

Power efficiency for very high temperature solar thermal cavity receivers  

Science.gov (United States)

This invention is an improved solar energy cavity receiver for exposing materials and components to high temperatures. The receiver includes a housing having an internal reflective surface defining a cavity and having an inlet for admitting solar radiation thereto. A photothermal absorber is positioned in the cavity to receive radiation from the inlet. A reflective baffle is positioned between the absorber and the inlet to severely restrict the re-radiation of energy through the inlet. The front surface of the baffle defines a narrow annulus with the internal reflective surface of the housing. The front surface of the baffle is contoured to reflect incoming radiation onto the internal surface of the housing, from which it is reflected through the annulus and onto the front surface of the absorber. The back surface of the baffle intercepts infrared radiation from the front of the ...

1984-01-01

451

Power efficiency for very high temperature solar thermal cavity receivers  

Energy Technology Data Exchange (ETDEWEB)

This invention is an improved solar energy cavity receiver for exposing materials and components to high temperatures. The receiver includes a housing having an internal reflective surface defining a cavity and having an inlet for admitting solar radiation thereto. A photothermal absorber is positioned in the cavity to receive radiation from the inlet. A reflective baffle is positioned between the absorber and the inlet to severely restrict the re-radiation of energy through the inlet. The front surface of the baffle defines a narrow annulus with the internal reflective surface of the housing. The front surface of the baffle is contoured to reflect incoming radiation onto the internal surface of the housing, from which it is reflected through the annulus and onto the front surface of the absorber. The back surface of the baffle intercepts infrared radiation from the front of the ...

1984-10-30

452

On Sensitivity of Spectral Radiative Fluxes to Atmospheric Water Vapor in the 940 nm Region (Numerical Simulation)  

Energy Technology Data Exchange (ETDEWEB)

Water vapor is well known to be a critical component in many aspects of atmospheric research, such as radiative transfer and cloud and aerosol processes. This requires both improved measurements of the columnar water vapor and its profiles in the atmosphere in a wide range of conditions, and adjustment of water vapor parameterizations in radiation codes including the perfection of spectroscopic parameters. In this paper we will present the results of comparison of our calculations and downward solar fluxes measured with Rotating Shadowband Spectroradiometer under conditions of horizontally homogeneous clouds. We also will discuss the sensitivity of atmospheric radiation characteristics to variations of water vapor in the band 940 nm: these results may be useful for development of new methods of retrieval of the total column water vapor content (WVC) in the atmosphere from data of radiation observations.

2005-03-18

453

Measurements of x-ray radiation dose levels during radiological examination in Jos university teaching hospital and Plateau state specialist hospital  

International Nuclear Information System (INIS)

In this project, measurement of x-ray radiation dose level during radiological examination in Jos university teaching hospital and Plateau State specialist hospital at different locations within the department were carried out using radiation survey meter. The results were converted from micro sievert per hour (#mu#Sv/hr) to milisievert per year (mSv/yr). The radiation levels from the two hospitals visited ranged from 1.3m Sv/yr to 8.4m Sv/yr. This implies that all the radiology departments visited are still operating within the safety limit having less than 20 mSv/yr which is the standard permissible radiation level recommended per year.

2008-10-15

454

Influence of the X-ray radiation on the lifetime of carriers in the p-n junctions of Si and Ge  

International Nuclear Information System (INIS)

Lifetime of minority charae carriers in the Si and Ge p-n unctions has been measured by pulse method of conductivity modulation of base. Its dependence on the X-ray radiation dose has been investigated. Dependence of current transmission coefficients on the dose has been measured and their sharp decrease at low doses and the following saturation at high doses have been observed. Linear dependence of lifetime on X-ray radiation dose has been obtained. Resulting from the comparison of regularities of the change of lifetime due to current characteristics, it has been shown that X-ray radiation leads to the formation of the surface defects, influencing the change of current characteristics as well as to stationary structural defects, causing the decrease of lifetime of the charge carriers with the increase of X-ray radiation dose.

455

Improved power efficiency for very-high-temperature solar-thermal-cavity receivers  

Energy Technology Data Exchange (ETDEWEB)

This invention is an improved solar energy cavity receiver for exposing materials and components to high temperatures. The receiver includes a housing having an internal reflective surface defining a cavity and having an inlet for admitting solar radiation thereto. A photothermal absorber is positiond in the cavity to receive radiation from the inlet. A reflective baffle is positioned between the absorber and the inlet to severely restrict the re-radiation of energy through the inlet. The front surface of the baffle defines a narrow annulus with the internal reflective surface of the housing. The front surface of the baffle is contoured to reflect incoming radiation onto the internal surface of the housing, from which it is reflected through the annulus and onto the front surface of the absorber. The back surface of the baffle intercepts radiation from the front of the absorber. ...

1982-04-14

456

Health risks arising from ionizing radiation and chemical pollutants  

International Nuclear Information System (INIS)

In quantifying health risks arising from radiation exposure and synergistic effects promoted by radiation the dose-effect relationship must be used as a basis. Special problems arise in the extrapolation of experimental results or in the treatment of data in the region of low doses administered over long periods of time. For radiation protection purposes, especially manifestations of cancer and genetic effects are significant. The International Commission on Radiation Protection has published binding guiding values on the basis of which to assess the risk of cancer. The cancer risk and genetic risks are estimated for relevant dose ranges and compared with other factors of civilization. For the most important chemical pollutants emitted into the environment the possibilities of impacts arising from synergistic effects are discussed on the basis of the rules and regulations specified in German ...

1979-10-03

457

Environmental Radiation Effects: A Need to Question Old Paradigms  

Energy Technology Data Exchange (ETDEWEB)

A historical perspective is given of the current paradigm that does not explicitly protect the environment from radiation, but instead, relies on the concept that if dose limits are set to protect humans then the environment is automatically protected as well. We summarize recent international questioning of this paradigm and briefly present three different frameworks for protecting biota that are being considered by the U.S. DOE, the Canadian government and the International Commission on Radiological Protection. We emphasize that an enhanced collaboration is required between what has traditionally been separated disciplines of radiation biology and radiation ecology if we are going to properly address the current environmental radiation problems. We then summarize results generated from an EMSP grant that allowed us to develop a Low Dose Irradiation Facility that specifically addresses effects of ...

2003-03-27

458

Effect of radiation on certain animal viruses in liquid swine manure  

International Nuclear Information System (INIS)

The virucidal effect of _6_0Co gamma radiation was studied in cell culture medium and in liquid swine manure involving the most important porcine viruses that can be spread by liquid manure. The radiation doses (20 kGy and 30 kGy) were determined in preliminary experiments employing a porcine enterovirus from the serogroup 1 (Teschen group). In the main experiment, the following viruses were employed: swine vesicular disease (SVD) virus, type C foot-and-mouth disease (FMD) virus, a field strain of Aujeszky's disease (AD) virus, transmissible gastroenteritis (TGE) virus, as well as bovine viral diarrhoea (BVD) virus. The latter strain served as a model for hog cholera virus. The results of the experiments indicate that safe disinfection of the virus infected liquid swine manure by ionizing radiation requires a radiation dose of 30 kGy. (author).

1983-01-01

459

Dosimetric considerations for patients with HIP prostheses undergoing pelvic irradiation. Report of the AAPM Radiation Therapy Committee Task Group 63  

International Nuclear Information System (INIS)

This document is the report of a task group of the Radiation Therapy Committee of the AAPM and has been prepared primarily to advise hospital physicists involved in external beam treatment of patients with pelvic malignancies who have high atomic number (Z) hip prostheses. The purpose of the report is to make the radiation oncology community aware of the problems arising from the presence of these devices in the radiation beam, to quantify the dose perturbations they cause, and, finally, to provide recommendations for treatment planning and delivery. Some of the data and recommendations are also applicable to patients having implanted high-Z prosthetic devices such as pins, humeral head replacements. The scientific understanding and methodology of clinical dosimetry for these situations is still incomplete. This report is intended to reflect the current state of scientific understanding and technical methodology in clinical ...

2003-06-01

460

Development of calibration facility for radiation protection monitoring instruments  

International Nuclear Information System (INIS)

Exposure control at the operating Nuclear Power Station is a major concern. The challenging task of meeting the International standards in the field of radiation protection is the calibration of the radiation monitoring instruments and interpretation of personnel and area monitoring results. Correct interpretation is based on accurate calibration of radiation measuring instruments. The reliability and accuracy of the measurements are also partly based on the procedures applied in calibration. Inadequate calibration can cause large errors in dose estimation in complete dose rate range and energy range. Semiautomatic calibration facility established at TAPS 3 and 4 for radiation monitoring instruments. Objective of calibration facility is (a) Ensure instruments are working properly (b) calibration adjustment and (c) in case without calibration adjustment to reveal the error involved. The calibration ...

2008-11-19

461

Coherent Smith-Purcell radiation in the far-infrared region from a short-bunched electron beam  

International Nuclear Information System (INIS)

Coherent Smith-Purcell radiation, emitted from short-bunched electrons passing by a lamellar-type grating of aluminum, has been observed in the millimeter wave region. The energy of the electrons is either 42 MeV when they are accelerated by an L-band linear accelerator or 150 MeV accelerated by an S-band one. The intensity of the radiation is proportional to the square of the beam current. The radiation is linearly polarized, and the electric vector of the radiation is in the plane defined by the observing point and the beam trajectory. The intensity decreases with the beam height, i.e. the distance of the beam from the surface of the grating, in accordance with the modified Bessel function of zeroth order. copyright 1996 American Institute of Physics.

1995-09-28

462

Circumsolar radiation telescope  

Energy Technology Data Exchange (ETDEWEB)

A circumsolar telescope for determining the flux of energy from the sun and from the circumsolar region as a function of angle, wavelength, and atmospheric conditions is presented. The telescope system consists of a specially designed scanning telescope, an electronic control and recording system and some auxiliary equipment. The detector is a pyroelectric crystal, a type of thermal detector, thus the fundamental measurement is relatively wavelength insensitive. The telescope is designed to provide data for all weather conditions during which a concentrating solar energy system would be operating. Analyses show that for a clear blue sky, the amount of radiation coming directly from the sun, while for a sky with thin clouds or haze, the circumsolar radiation is some 25% of the direct solar radiation. Under such conditions a measure of the circumsolar radiation is necessary for an accurate prediction of ...

1980-01-01

463

Chain radiation-chemical cross-linking of polyethylene under high pressures. [Gamma radiation  

Energy Technology Data Exchange (ETDEWEB)

Regularities in the radiation cross-linking of low-density polyethylene under various conditions of ..gamma..-irradiation were studied. It is shown that at the 0.5 GPa pressure and 450 K the gel formation is initiated at doses of about 1 kGy, i.e. at doses 10 times as low as compared to normal conditions. Abnormally high rate of radiation cross-linking at high temperature and high pressure is an evidence of changes in the mechanism of polyethylene, radiation cross-linking, i.e. of the process transition from nonchain to chain conditions. Decrease in the potential barriers of macroradical reactions with macromolecules is the most probable reason of change in the polymer cross-linking nature.

1984-01-01

464

Behaviour Features of the Radiative Losses of the Torsatron U-3M Plasma  

International Nuclear Information System (INIS)

The total bolometrically measured plasma radiation losses on the RF heating power were found. The results of measurements demonstrate a nonmonotonic dependence of radiation losses on RF power. Namely, at low RF power levels (80...170 kW) the total radiation losses raised with increasing the RF power. However, the total radiation losses decreased sharply when RF power exceeded 200 kW (down to ?20 kW at 240 kW of RF power). Simultaneously, the intensity of impurity lines fell down significantly, whereas the average electron temperature (found from ECE measurement) increased. The authors consider that screening properties of periphery plasma give reasons for above experimental facts.

2006-01-01

465

The preliminary success of ALARA implementation in Daya Bay NPP  

International Nuclear Information System (INIS)

Based on the practical condition of the plant and in reference to advanced management experiences worldwide, Daya Bay Nuclear Power Plant has established its own peculiar management system for radiation protection management and ALARA implementation. The characteristics of the system are: radiation protection training to all workers, active involvement of all managers and staffs, and whole process safety control to maintenance activities. The management philosophy of 'workers are responsible for their own radiation safety' is adopted in the plant. A strict, formalized and systematic whole staff radiation protection training, evaluation, authorization and periodically refreshing mechanism had been established and executed in the plant. In the organizational point of view, the responsibilities of line managers were specified in plant procedures, ALARA coordination organization on plant level and for ...

2000-05-01

466

Reduction in radiation-induced brain injury by use of pentobarbital or lidocaine protection  

Energy Technology Data Exchange (ETDEWEB)

To determine if barbiturates would protect brain at high doses of radiation, survival rates in rats that received whole-brain x-irradiation during pentobarbital- or lidocaine-induced anesthesia were compared with those of control animals that received no medication and of animals anesthetized with ketamine. The animals were shielded so that respiratory and digestive tissues would not be damaged by the radiation. Survival rates in rats that received whole-brain irradiation as a single 7500-rad dose under pentobarbital- or lidocaine-induced anesthesia was increased from between from 0% and 20% to between 45% and 69% over the 40 days of observation compared with the other two groups (p less than 0.007). Ketamine anesthesia provided no protection. There were no notable differential effects upon non-neural tissues, suggesting that pentobarbital afforded protection through modulation of ambient neural activity during radiation ...

1990-05-01

467

Radiation thermocatalytic processes of hydrogen production from water  

International Nuclear Information System (INIS)

The results of studies of radiation-thermocatalytic water decomposition in the 673-773 K temperature range in the presence of BeO and titanium Y-type zeolite are presented. It is found that radiation-thermocatalytic processes of hydrogen production from water are characterized by a lower activation energy (55.4 kJ/mole) as compared with thermocatalytic processes (88.4 kJ/mole). The radiation-thermocatalytic process rate in the presence of oxide systems is not an additive sum of rates of radiation-catalytic (at 296-300 K) and thermocatalytic processes of water decomposition. On the basis of obtained results the conclusion is made that during radiation-catalytic decomposition of water in a heterogeneous system BeO + H_2O the main contribution into this process is made by excitons, radiation-chemical yields of excitons and non-equilibrium charge-carriers are ...

468

Radiation processing of wood-plastic composites  

International Nuclear Information System (INIS)

There are three main types of radiation-processed composite material derived from plastics and fibrous natural polymers. The first are the monomer-impregnated, radiation-treated wood-plastic composites (WPC). They became a commercial success in the early 1970s. More recently, work has focused on improving the WPCs by creating in them interpenetrating network (IPN) systems by the use of appropriate multifunctional oligomers and monomers. The main kinetic features of radiation-initiated chain polymerization remain applicable even in impregnated wood. The second type are the plastics filled or reinforced with dispersed wood fiber or other cellulosics (WFRP). In their case, radiation processing offers a new opportunity to apply radiation-reactive adhesion promoters between wood or cellulosic fibers and the thermoplastic matrices. The third type are the laminar composites made by ...

469

Radiation processing in Hungary  

Energy Technology Data Exchange (ETDEWEB)

Hungary has 10.7 million population in 100,000 km/sup 2/ territory. The gross national product is about $3,000 per capita per year. Hungary is a country with highly developed agriculture and medium degree developed industries. The Hungarian economy is an open economy because more than 40% of the national income is earned by export. The research and development works on various radiation processing have been performed for 25 years. In the Central Research Institute for Physics of the Hungarian Academy of Sciences, a laboratory was organized for the basic research of radiation chemistry and the moderator materials for nuclear reactors. Also the activities in the Central Research Institute for Chemistry, the Institute of Isotopes, the Research Institute for Plastics Industry, and the Central Research Institute for Food Industry are briefly reported. The largest radiation processing unit in Hungary is the automatic ...

1982-01-01

470

Radiation hardening of final optics for an ICF reactor  

International Nuclear Information System (INIS)

Radiation damage of the final optical components in an Inertial Confinement Fusion (ICF) reactor is a crucial issue for development of a laser-fusion reactor. To some extent, this problem will be encountered in the National Ignition Facility (NIF), but there, the integrated radiation dose will be considerably less than that encountered in a future reactor. This extremely harsh radiation environment necessitates shielding the ICF optics from direct neutron and x-ray bombardment. Several approaches have been suggested, such as the use of grazing incidence metal mirrors or fused silica wedge deflectors. While metal mirrors can withstand a larger radiation dose, their focusing qualities pose problems. Therefore wedge deflectors, originally suggested by Lawrence Livermore National Laboratory (LLNL) staff, represent a promising alternative. Radiation hardening of the fused silica ...

1995-04-24

471

Radiation hardening of CMOS-based circuitry in SMART transmitters  

International Nuclear Information System (INIS)

Process control transmitters that incorporate digital signal processing could be used advantageously in nuclear power plants; however, because such transmitters are too sensitive to radiation, they are not used. The Electric Power Research Institute sponsored work at Sandia National Laboratories under EPRI contract RP2614-58 to determine why SMART transmitters fail when exposed to radiation and to design and demonstrate SMART transmitter circuits that could tolerate radiation. The term ''SMART'' denotes transmitters that contain digital logic. Tests showed that transmitter failure was caused by failure of the complementary metal oxide semiconductors (CMOS)-integrated circuits which are used extensively in commercial transmitters. Radiation-hardened replacements were not available for the radiation-sensitive CMOS circuits. A conceptual design showed that a ...

472

Radiation effects on MOS devices and radiation-hard CMOS technologies  

International Nuclear Information System (INIS)

Total-dose irradiation seriously damages MOS devices and their circuit performance. Threshold voltage shifts, transconductance degradation and increase in off-state leakage current are generally observed for irradiated devices. These instabilities are essentially due to positive and/or negative charge trapping in SiO_2 and interface trap generation at the SiO_2/Si interface. Radiation hardening of CMOS VLSIs is to eliminate these trapping effects, and for this purpose, special considerations for fabrication processes and layout design are necessary. In this paper, basic mechanisms for radiation-induced charge trapping and related effects on MOS devices are reviewed. Also discussed are radiation-hardening technologies from both fabrication-process and layout-design viewpoints. Using these technologies, 1 #mu#m radiation-hard CMOS gate arrays have been successfully developed. Experimental data taken for ...

473

Performance evaluation of the conventional Brazilian industries radiation protection in the small industrial gauges and industrial radiography areas; Sistema de avaliacao de desempenho em radioprotecao das industrias convencionais brasileiras nas areas de medidores nucleares e radiografia industrial  

Energy Technology Data Exchange (ETDEWEB)

This works evaluates by punctuation the performance in conventional Brazilian industries radiation protection area which make use of small industrial gauges and industrial radiography. It proposes, procedures for industry self-evaluation, besides a new radiation protection plans pattern for the small industrial gauges area. The data source where inspection reports of Dosimetry Radiation Protection Institute/Nuclear Energy Commission conventional Brazilian industries' radiation protection plans, beyond visitation to the inspection place. The performance evaluation has been realized both in the administrative and operational aspects of the industries. About of 60% of the industries have a satisfactory register control which does not happen to the operational control. The performance evaluation advantage is that industries may self-evaluate, foreseeing Dosimetry Radiation ...

1999-08-01

474

Modulating factors in the expression of radiation-induced oncogenic transformation  

Energy Technology Data Exchange (ETDEWEB)

Many assays for oncogenic transformation have been developed ranging from those in established rodent cell lines where morphological alteration is scored, to those in human cells growing in nude mice where tumor invasiveness is scored. In general, systems that are most quantitaive are also the least relevant in terms of human carcinogenesis and human risk estimation. The development of cell culture systems has made it possible to assess at the cellular level the oncogenic potential of a variety of chemical, physical and viral agents. Cell culture systems afford the opportunity to identify factors and conditions that may prevent or enhance cellular transformation by radiation and chemicals. Permissive and protective factors in radiation-induced transformation include thyroid hormone and the tumor promoter TPA that increase the transformation incidence for a given dose of radiation, and retinoids, selenium, vitamin E, and ...

1990-08-01

475

Modulating factors in the expression of radiation-induced oncogenic transformation  

International Nuclear Information System (INIS)

Many assays for oncogenic transformation have been developed ranging from those in established rodent cell lines where morphological alteration is scored, to those in human cells growing in nude mice where tumor invasiveness is scored. In general, systems that are most quantitaive are also the least relevant in terms of human carcinogenesis and human risk estimation. The development of cell culture systems has made it possible to assess at the cellular level the oncogenic potential of a variety of chemical, physical and viral agents. Cell culture systems afford the opportunity to identify factors and conditions that may prevent or enhance cellular transformation by radiation and chemicals. Permissive and protective factors in radiation-induced transformation include thyroid hormone and the tumor promoter TPA that increase the transformation incidence for a given dose of radiation, and retinoids, selenium, vitamin E, and ...

1990-01-01

476

How to overestimate risks of ionizing radiations  

International Nuclear Information System (INIS)

Ignoring the numerous, known and mainly unknown, interactions between chemicals and ionizing radiations, causes strong controversy about the risks of ionizing radiations. Yet the best known interactions between chemicals and radiations is that between radon and tobacco smoke. Although it is and it will be always impossible to derive quite quantitative laws for this interaction, it has been possible to derive some semi-quantitative relationships based on reasonable assumptions and statistics on lung cancer deaths in developed countries. They show that ignoring the dangers of tobacco smoking as we did still long after we had recognised the dangers of radiations, could asses to radiations thirty or forty times more risks than reality. As present world is flown by tens of thousands chemicals, little or not present in a natural environment, and as it would be very surprising that some ...

477

Effectiveness of radiation therapy after surgery for hilar cholangiocarcinoma  

International Nuclear Information System (INIS)

Some studies suggest that giving radiation therapy after surgery for hilar cholangiocarcinoma improves the survival rate; however, many of these studies did not specify numbers of subjects or provide an impartial analysis. Thus, we evaluated the effectiveness of radiation therapy as adjuvant treatment after surgery and attempted to establish appropriate adaptation standards. We reviewed the records of 69 patients who underwent surgery for hilar cholangiocarcinoma between June 1980 and April 1998. Thirty-nine patients were treated with surgery followed by radiation therapy and 30 were treated with surgery alone. The clinicopathologic features that might have influenced prognosis were similar in the patients who received radiation therapy and those who did not. Radiation as adjuvant therapy did not have a beneficial effect on overall survival (P=0.554, log-rank test); however, it ...

2005-07-01

478

Effect of radiation dose on the properties of natural rubber nanocomposite  

Energy Technology Data Exchange (ETDEWEB)

Effect of radiation dose and carbon nanotubes (CNT) on the mechanical properties of standard Malaysian rubber (SMR) was investigated in this study. SMR nanocomposites containing 1-7 phr CNT were prepared using the solvent casting method and the nanocomposites were radiated at doses of 50-200 kGy. The change in mechanical properties, especially, tensile strength (Ts), elongation at break (Eb), hardness and tensile modulus at 100% elongation (M{sub 100}) were studied as a function of radiation dose. The structure and morphology of reinforced natural rubber was investigated by FESEM, TEM and AFM in order to gain further evidence on the radiation-induced crosslinking. It was found that the Ts, M{sub 100} and the hardness of the SMR/CNT nanocomposites significantly increased with radiation dose; the elongation at break exhibited an increase up to 100 kGy, and a downward trend thereafter. ...

2010-12-15

479

Effect of antioxidants on aging of nuclear plant cable insulation  

International Nuclear Information System (INIS)

The effects of various antioxidants and antioxidant concentrations on the radiation and thermal stability of EPDM and XLPE polymers used for insulation of electric cable in nuclear power plants were measured. The objective was to determine if particular antioxidants could be identified as being especially effective for stabilization against radiation aging and combined thermal and radiation aging. Elongation to rupture was used as the measure of stability. Materials were irradiated to doses up to 2 MGy (200 Mrad) at a dose rate of 200 to 300 Gy/h in the Cobalt-60 Gamma Irradiation Facility at the University of Virginia. All of the antioxidants tested, which were known to provide excellent thermal stability, also provided good stability for radiation aging and combined thermal/radiation aging, although small differences between antioxidants were noted. No antioxidant or antioxidant ...

480

Acousto-optic multiplexing and demultiplexing  

Energy Technology Data Exchange (ETDEWEB)

A system is claimed for multiplexing or demultiplexing pulsed laser radiation having an acousto-optical device which is electrically controlled to switch a common path of high pulse rate laser radiation between a plurality of spatially distinct paths for relatively lower pulse rate laser radiation at which the pulses are sequenced according to a predetermined time pattern. The acousto-optical element typically includes a Bragg cell which is electrically driven by a set of distinct frequencies, causing deflection of radiation passing therethrough at a predetermined set of angles whereby pulsed radiation on a single path may be distributed onto the plural separate paths or radiation on plural separate paths of time-sequenced pulses of radiation can be combined into a single path of augmented pulse rate. The control of the acousto-optical ...

1980-06-03

481

A study on the real-time radiation dosimetry measurement system based on optically stimulated luminescence  

Science.gov (United States)

The optically stimulated luminescent (OSL) radiation dosimeter technically surveys a wide dynamic measurement range and a high sensitivity. Optical fiber dosimeters provide capability for remote monitoring of the radiation in the locations which are difficult-to-access and hazardous. In addition, optical fiber dosimeters are immune to electrical and radio-frequency interference. In this paper, a novel remote optical fiber radiation dosimeter is described. The optical fiber dosimeter takes advantage of the charge trapping materials CaS:Ce, Sm that exhibit OSL. The measuring range of the dosimeter is from 0.1 to 100 Gy. The equipment is relatively simple and small in size, and has low power consumption. This device is suitable for measuring the space radiation dose and also can be used in high radiation dose condition and other dangerous radiation occasions. ...

2008-05-01

482

Trans-generational radiation-induced chromosomal instability in the female enhances the action of chemical mutagens  

Energy Technology Data Exchange (ETDEWEB)

Genomic instability can be produced by ionising radiation, so-called radiation-induced genomic instability, and chemical mutagens. Radiation-induced genomic instability occurs in both germinal and somatic cells and also in the offspring of irradiated individuals, and it is characterised by genetic changes including chromosomal rearrangements. The majority of studies of trans-generational, radiation-induced genomic instability have been described in the male germ line, whereas the authors who have chosen the female as a model are scarce. The aim of this work is to find out the radiation-induced effects in the foetal offspring of X-ray-treated female rats and, at the same time, the possible impact of this radiation-induced genomic instability on the action of a chemical mutagen. In order to achieve both goals, the quantity and quality of chromosomal damage were ...

2008-04-02

483

Short-term inhibition of ADP-induced platelet aggregation by clopidogrel ameliorates radiation-induced toxicity in rat small intestine.  

Science.gov (United States)

Endothelial dysfunction and increased platelet aggregation may be involved in the pathogenesis of normal tissue radiation toxicity. This study assessed clopidogrel, an inhibitor of ADP-induced platelet aggregation, as a modulator of intestinal radiation injury (radiation enteropathy). Rat small intestine was exposed to 21 Gy X-radiation. Clopidogrel (20 mg/kg/day) or vehicle was administered from 2 days before to 10 days after irradiation. Structural radiation injury, neutrophil infiltration, smooth muscle cell proliferation, collagen content, and TGF-beta1 expression were assessed 2 weeks (early phase) and 26 weeks (delayed phase) after irradiation, using quantitative histology and immunohistochemistry, morphometry, and real-time fluorogenic probe RT-PCR. Irradiated intestine exhibited significant histopathologic injury, reduced mucosal surface area, vascular sclerosis, intestinal ...

2002-01-01

484

Physical, biochemical and physiological effects of ultraviolet radiation on Brassica napus and Phaseolus vulgaris  

International Nuclear Information System (INIS)

In order to follow some of the changes induced by ultraviolet-B (UV-B, 280-320 nm) radiation in Phaseolus vulgaris and Brassica napus, experiments were designed to localize sites of changes in leaves and to correlate some of the physiological and biochemical changes with penetration of UV-B radiation. B.napus was exposed to 8.9 kJ m"-"2 day"-"1 biologically effective UV-B radiation (UV-B_B_E). The penetration of UV-B radiation into the leaf was followed using a quartz fibre optic microprobe. Monochromatic radiation at 310 nm was decreased by ca 50 and 34% in the adaxial and abaxial epidermis, respectively, in plants not exposed to UV-B, whereas the radiation was decreased by ca 70 and 42%, respectively, in the same region in UV-treated plants. Polychromatic radiation showed a wavelength dependent change mainly for the collimated ...

1991-11-05

485

Natural background radiation induces cytogenetic radioadaptive response more effectively than occupational exposure in human peripheral blood lymphocytes  

Science.gov (United States)

Ramsar, a city in the northern Iran, has the highest level of natural background radiation in the world. It has been clearly shown that low doses of ionising radiation can induce resistance to subsequent higher exposures. This phenomenon is termed radioadaptive response. We have compared induction of cytogenetic radioadaptive response by High Natural Background Radiation (HNBR) in Ramsar and X-ray occupational exposure as conditioning doses in human peripheral blood lymphocytes. 30 healthy control individuals, living in Ramsar but in normal background radiation areas, 15 healthy individuals from Talesh Mahalleh, a region with extraordinary high level of background radiation, and 7 X-ray radiographers working in Ramsar hospital located in normal natural background ionising radiation area were evaluated. Peripheral blood samples were prepared and exposed to ...

2003-01-01

486

Experimental chemo- and radio-therapy on human cholangiocarcinoma transplanted to nude mice  

International Nuclear Information System (INIS)

A human cholangiocarcinoma, Ch-1, serially transplanted to nude mice was used for experimental chemotherapy, radiotherapy, and conbination chemoradiotherapy. In the group of chemotherapy with single drug, Mitomycin C (MMC) revealed greater effectiveness than Adriamycin in terms of tumor regression, histological findings, and minor side effects. MMC and radiotherapy by Linac X-ray showed exponential linear dose response curve against tumor weight. Their effects were equivalent at doses of MMC 1 mg/kg and radiation 1,000 rads/mouse in the changes of tumor weight and of histological findings which were similar to each other. Combination chemoradiotherapy showed the synergistic action when the radiation (500 rads/mouse) was performed before MMC (0.5 mg/kg) administration, whereas only the additive effect was observed when the sequence was reversed. The cell kinetic analysis was performed by the impulse cytophotometry, "3H-thymidine uptake labeling ...

487

Application of radiation in Bangladesh  

International Nuclear Information System (INIS)

Radiation technology offers a very wide scope for utilisation and commercial exploitation in various field. All over the world, this technology is being favourably considered for different applications like radiation sterilisation of medical products, preservation of food by controlling the physiological processes for extending shelf-life and eradication of microbial and insect pests, radiation processing of polymeric materials and treatment of sewage sludge. Bangladesh Atomic Energy Commission has taken radiation processing programmes in a big way right from its inception. This paper describes the studies carried out by various research groups in Bangladesh Atomic Energy Commission mainly using Cobalt-60 gamma radiation. The investigation covers medical sterilisation, food preservation and development and modification of polymeric materials by gamma radiation. ...

2001-03-01

488

Ultraviolet radiation in Finland  

Energy Technology Data Exchange (ETDEWEB)

Solar ultraviolet radiation is damaging for living organisms due to its high energy pro each photon. The UV radiation is often separated into three regions according to the wavelength: UVC (200-280 nm), UVB (280-320 nm) and UVA (320-400 nm). The most hazardous part, UVC is absorbed completely in the upper atmosphere by molecular oxygen. UVB radiation is absorbed by atmospheric ozone partly, and it is reaching Earth`s surface, as UVA radiation. Besides atmospheric ozone, very important factors in determining the intensity of UVB radiation globally are the solar zenith angle and cloudiness. It may be calculated from global ozone changes that the clear-sky UVB doses may have enhanced by 10-15 % during spring and 5-10 % during summer at the latitudes of Finland, following the decrease of total ozone between 1979-90. The Finnish ozone and UV monitoring activities have become a part of ...

1996-12-31

489

Treatment of cancer of the pancreas by intraoperative electron beam therapy: physical and biological aspects  

Energy Technology Data Exchange (ETDEWEB)

Radiation therapy has had a significant and an expanded role in the management of cancer of the pancreas during the last decade. In particular, for locally advanced disease, radiation therapy has improved the median survival of patients to 1 year. Intraoperative electron beam therapy has been applied to unresectable and resectable pancreatic cancer in an attempt to enhance local control of disease and to improve patient survival. This paper presents a survey of the role of radiation therapy in treatment of cancer of the pancreas, provides information on the radiobiological aspects of this treatment modality and details the physical and dosimetric characteristics of intraoperative radiation therapy with electrons. Presented are the design specifics of an applicator system, central axis beam data, applicator parameters, dose distribution data, shielding, treatment planning and means of verification. ...

1989-01-01

490

Treatment of cancer of the pancreas by intraoperative electron beam therapy: physical and biological aspects  

International Nuclear Information System (INIS)

Radiation therapy has had a significant and an expanded role in the management of cancer of the pancreas during the last decade. In particular, for locally advanced disease, radiation therapy has improved the median survival of patients to 1 year. Intraoperative electron beam therapy has been applied to unresectable and resectable pancreatic cancer in an attempt to enhance local control of disease and to improve patient survival. This paper presents a survey of the role of radiation therapy in treatment of cancer of the pancreas, provides information on the radiobiological aspects of this treatment modality and details the physical and dosimetric characteristics of intraoperative radiation therapy with electrons. Presented are the design specifics of an applicator system, central axis beam data, applicator parameters, dose distribution data, shielding, treatment planning and means of verification. ...

491

Radiation resistance of nylon. [Gamma radiation  

Energy Technology Data Exchange (ETDEWEB)

Various nylons including nylon 6, nylon 66, nylon 610 and nylon 12 in the forms of fiber and film were irradiated with the gamma-ray from Co-60 at the dose rate of 0.12 Mrad/hr in the atmosphere of oxygen at 7 kg/cm/sup 2/ and at the room temperature. The irradiation in vacuum on the same specimens was performed at 0.5 Mrad/hr. The tensile properties and the gel fraction of the irradiated nylon samples were measured, and the radiation resistance of the nylons against the irradiation at low dose rate was estimated. From the experimental results, it became clear that in the case of irradiation in vacuum, all the nylons were durable to the irradiation of 250 Mrad or more, and nylon 6 was more durable than nylon 12, and in the case of irradiation in pressurized oxygen, the radiation resistance of the nylons decreased to one-tenth as compared with that in vacuum, and contrary to that in vacuum, nylon 12 was superior to nylon 6, while nylon 610 was ...

1983-12-01

492

Organisms posses enzymes that function in the repair of DNA damaged by radiations, chemicals and metabolic events  

International Nuclear Information System (INIS)

This report briefly describes the studies on the mechanism of in vivo DNA repairing by the author in Research Reactor Institute, Kyoto Univ. for the past 30 years. First, the ability of UV radiation to induce transformation was investigated with viral DNA. The formation of thymine-thymine dimer was found harmful to organisms and such dimers were removable by UV-radiation at a low frequency. The mutability was determined in three different E.coli strains with mutator gene, mutT, mutS or mutL. The ability to excise 8-oxoguanin developed in primer DNA was deficient in mutT and miss-pairing left after DNA replication could not be recovered in mutL and mutS strains. Further, DNA repairing mechanism was investigated in other microorganisms; single-strand cleavage caused by exposure to BNCB radiation (boron-neutron-captured beam) could not be repaired in E. coli. Whereas for Deinococcus radiodurans, of which survival rate was not ...

1998-01-01

493

On the space-time scales of the surface solar radiation field  

Energy Technology Data Exchange (ETDEWEB)

The characteristic space-time scales of surface solar radiation fields measured by the 111-instrument ME-SONET in Oklahoma are estimated after removal of the diurnal cycle. These estimates of {open_quotes}within-day{close_quotes} are used to deduce the representativeness of surface solar radiation measurements measurement site as a function of time-averaging interval. Nomograms of the relation between point measurements and area averages are given for different space-time-averaging intervals. Examples from the nomograms show, for instance, that under conditions of low mean radiation (cloudy days), the central site point measurements are representative of a spatial area the size of a T42 GCM grid box (280 km X 280 km) if one uses hourly averages and is willing to accept a correlation of 0.45 between area average and point measurement. The point data represent a 60 km X 60 km region at a 0.90 correlation level if a 5-min time ...

1998-01-01

494

Manufacture of wood/plastic composites by radiation  

International Nuclear Information System (INIS)

The manufacture and use of wood/plastic composite (WPC) as an example of wood matrix and wood sawdust/plastic composites (SDP) as an example of plastic matrix are reviewed. The raw material for WPC are mostly vinyl monomers, particularly methyl methacrylate and styrene. The reaction in WPC polymerization is radical polymerization. Researches on the radiation sources mostly resulted in gamma-ray. Electron beam can be applied only to thin products. The future use of WPC may be for furnitures, sporting goods, decorative parts and the like. Vital study on the reduction of manufacturing costs is required, for example, the improvement of reaction and the adoption of continuous process must be considered. The raw materials for SDP are wood sawdust, vinyl monomer (mostly methyl methacrylate) and resins. Electron beam accelerators are the most preferable radiation source because of its high efficiency and safe operation. SDP shows good forming property. ...

1976-01-01

495

Environmental hardening of a mobile-manipulator system for nuclear environments  

International Nuclear Information System (INIS)

This research report discusses the radiation hardening of a commercially available mobile robot, the REMOTEC ANDROS. This hardening effort is culminating in the availability of a megarad hardened mobile platform to access areas in nuclear facilities with extremely high levels of radiation (0.1 to 1 Mrad). These radiation levels may be encountered both during routine repair and monitoring activities and accident situations. The project has completed a phase-I U.S. Department of Energy Small Business Innovative Research contract and is now in a phase-II effort with completion scheduled in early 1995. The research involves the evaluation of the material and electrical components of an ANDROS robot to determine the anticipated radiation hardness of the current production version and evaluation of the components that must be replaced or modified to harden the system to higher radiation ...

1993-11-14

496

Effective per-capita dose as a yardstick for medical radiation exposure of the population - a supplement or an alternative to the genetically significant dose  

International Nuclear Information System (INIS)

The genetically significant dose (GSD) is an index variable which exclusively allows to describe the genetic risk in the progeny of a population due to the application of ionizing radiation and radioactive substances in one part of this population. It may result in wrong interpretation of population exposure at increasing incidence of examinations in a population involving ionizing radiation and radioactive drugs at simultaneously increasing application of alternative methods in children and adolescents owing to the fact that it indicates a downward trend although somatic exposure of this population has increased. Therefore, it is recommended to state both the GSD and the level of somatic radiation exposure of the population taken from the individual sources for the comparison and assessment of radiation exposure from various sources in future. Although the somatically significant dose constitutes the ...

1984-06-01

497

Average neutron resonance parameters and radiative capture cross sections for the isotopes of molybdenum  

International Nuclear Information System (INIS)

The neutron capture cross sections of the stable molybdenum isotopes have been measured with high energy resolution (#DELTA#E/E < approximately 0.2%), between 3 and 90 keV neutron energy, at the 40 m station of ORELA. Average resonance parameters are extracted for s- and p-wave resonances. The s-wave neutron strength function is close to 0.5x10"-"4 for all isotopes, but the p-wave strength function exhibits a well defined peak near A approximately 95. Both s- and p-wave radiative widths decrease markedly as further neutrons are added to the closed shell. The p-wave radiative widths are generally greater than the s-wave widths showing the presence of non-statistical #gamma#-decay mechanisms. Valence neutron theory fails to explain the magnitude of the p- to s-wave radiative width disparity and doorway state processes are invoked. In particular, the data for "9"8Mo appear to violate the usual valence theory, since the ...

498

Animal models of ionizing-radiation damage. Technical report, 18 May 88-18 May 91  

Energy Technology Data Exchange (ETDEWEB)

This report is a survey of the English language literature of radiation biology between 1947 and 1987, for the purpose of compiling a literature base on the effects of radiation on animals, which have yielded results that can expand our knowledge about similar radiation effects on human beings. Articles were sought that reported exposure of adult mammals to external sources of ionizing radiation, having endpoints that included effects on the brain, the spinal cord, and behavior of the gastrointestinal, endocrine, and cardiovascular systems and the hematopoietic and immune systems. Effects of interest were those that occurred within the first 12 months after exposure. The survey does not include articles reporting chronic or long term delayed effects of radiation unless they provided insight into mechanisms of morphological and/or functional derangement. Information presented in the ...

1992-01-01