UK PubMed Central (United Kingdom)

Vascular endothelial growth factor (VEGF) plays a critical role in normal development as well as retinal vasculature disease. During retinal vascularization, VEGF is most strongly expressed by not yet...Full Text Available

UK PubMed Central (United Kingdom)

Seventy-seven patients developed retinal breaks following an episode of ocular contusion, and 65 (84.4%) of these developed rhegmatogenous retinal detachment. Surgical treatment successfully restored...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

UK PubMed Central (United Kingdom)

Unlike in normal rabbits, pulmonary rapidly adapting receptors (RARs) in rabbits with chronic mitral regurgitation (MR) do not respond to small changes in extravascular...Full Text Available

UK PubMed Central (United Kingdom)

Knowledge about retinal photoreceptor signal transduction and the visual cycle required for normal eyesight has expanded exponentially over the past decade. Substantial progress in human genetics...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

In several vertebrate classes, the M?ller glia are capable of de-differentiating, proliferating, and acquiring a progenitor-like state in response to acute retinal injury or in response to exogenous growth factors. Our previous study has shown that M?ller cells can be activated and de-differentiated into retinal progenitors during Royal College of Surgeons (RCS) rats' degeneration, although the limited proliferation cannot maintain retinal function. We now report that rat retinal stem cells (rSCs) transplanted into RCS rats slowed the progression of retinal morphological degeneration and prevented the functional disruption. Further, we found that retinal progenitor cells labeled with Chx10 were increased significantly after rSCs transplantation, and most of them are mainly from activated M...

UK PubMed Central (United Kingdom)

Three patients are described with foveal lesions resembling minute holes following trauma. The similarity of the lesions to foveomacular retinitis and solar retinopathy suggests that all these conditions...Full Text Available

KoreaScience (Korea)

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Science.gov (United States)

A critical element of a retinal prosthesis is the stimulating electrode array, which is placed in close proximity to the retina. It is via this retinal-electrode interface that a retinal prosthesis electrically stimulates nerve cells to produce the perception of light. The impedance load seen by the current driver consists of the tissue resistance and the complex electrode impedance. The results in this paper show that the tissue resistance of the retina is significantly greater than that of the vitreous humor in the eye. Circuit models of the electrode-retina interface are used to parameterize the different contributors to the overall impedance.

KoreaScience (Korea)

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UK PubMed Central (United Kingdom)

We have developed a new strategy for immunization of wild rabbit populations against myxomatosis and rabbit hemorrhagic disease (RHD) that uses recombinant viruses based on a naturally attenuated field...Full Text Available

DEFF Research Database (Denmark)

Aldosterone has been suggested to elicit vessel contraction via a nongenomic mechanism. We tested this proposal in microdissected, perfused rabbit renal afferent arterioles. Aldosterone had no effect on internal diameter in concentrations from 10(-10) to 10(-5) mol/L, but aldosterone abolished the ability of 100 mmol/L KCl to induce vascular contraction. The inhibitory effect of aldosterone was observed from 1 pmol/L. The inhibitory effect was significant after 5 minutes and maximal after 20 minutes and was fully reversible. Actinomycin D (10(-6) mol/L) prolonged the effect of aldosterone. The effect was abolished by the mineralocorticoid receptor antagonist spironolactone (10(-7) mol/L) but not by the glucocorticoid receptor antagonist mifepristone (10(-6) mol/L). The K+-mediated increase of intracellular calcium concentration in afferent arterioles was not affected by aldosterone. Mineralocorticoid receptor was detected by reverse ...

KoreaScience (Korea)

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KoreaScience (Korea)

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International Nuclear Information System (INIS)

To evaluate the effect of plugging the biopsy tract in rabbit liver and the pathologic changes caused by plugging materials. Thirty-two New Zealand White rabbits were divided into four groups (eight rabbits in each) and compared with one another. They were labeled group A (control), B (gelfoam), C (fibrin sealant) or D (NBCA). the liver was exposed and biopsied with an 18G disposable biopsy gun. The inner Tru-cut needle was withdrawn and plugging was undertaken through the outer cannula of the biopsy gun. Bleeding times of each material were compared. The rabbits were sacrificed and pathologically evaluated for 17 days.

UK PubMed Central (United Kingdom)

PurposeTo present full ophthalmologic examination and retinal nerve fiber layer (RNFL) photographs of autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) patients...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundSubjects with a ring scotoma can use two retinal loci, a foveal and a peripheral, for reading. Our aim was to investigate the relative use of both retinal loci as a function...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundRetinitis pigmentosa (RP) is characterized by progressive night blindness, visual field loss, altered vascular permeability and loss of central vision. Currently there...Full Text Available

UK PubMed Central (United Kingdom)

Using the photopigment melanopsin, intrinsically photosensitive retinal ganglion cells (ipRGCs) respond directly to light to drive circadian clock resetting and pupillary constriction. We now...Full Text Available

UK PubMed Central (United Kingdom)

Retinal degenerative diseases, such as retinitis pigmentosa and Leber congenital amaurosis, are a leading cause of untreatable blindness with substantive impact on the quality of life of affected individuals...Full Text Available

UK PubMed Central (United Kingdom)

Over 200 mutations in the retina specific member of the ATP-binding cassette transporter super-family (ABCA4) have been associated with a diverse group of human retinal diseases....Full Text Available

UK PubMed Central (United Kingdom)

Bisretinoid lipofuscin compounds that accumulate in retinal pigment epithelial (RPE) cells are implicated in the pathogenesis of some forms of macular degeneration. In the development of approaches...Full Text Available

UK PubMed Central (United Kingdom)

Fast and efficient high-throughput techniques are essential for the molecular diagnosis of highly heterogeneous hereditary diseases, such as retinitis pigmentosa (RP). We had previously approached RP...Full Text Available

UK PubMed Central (United Kingdom)

PurposeHyperglycemia and hypertension contribute to the development of diabetic retinopathy, and this may involve alterations in the normal retinal cell cycle. In this work, we examined...Full Text Available

Science.gov (United States)

A critical element of a retinal prosthesis is the stimulating electrode array, which is placed in close proximity to the retina. It is via this retinal-electrode interface that a retinal prosthesis electrically stimulates nerve cells to produce the perception of light. The impedance load seen by the current driver consists of the tissue resistance and the complex electrode impedance. The results in this paper show that the tissue resistance of the retina is significantly greater than that of the vitreous humor in the eye. Circuit models of the electrode-retina interface are used to parameterize the different contributors to the overall impedance. PMID:17325413

UK PubMed Central (United Kingdom)

The effects of homologous plasma HDL and VHDL fractions on established atherosclerotic lesions were studied in cholesterol-fed rabbits. Atherosclerosis was induced by feeding the animals a 0.5% cholesterol-rich...Full Text Available

UK PubMed Central (United Kingdom)

The cottontail rabbit papillomavirus (CRPV)/rabbit model has been used to study oncogenicity and immunogenicity of different antigens from the papillomavirus genome and has therefore served...Full Text Available

UK PubMed Central (United Kingdom)

The efficacy of beta-lactam antibiotics and amikacin alone and in various combinations against Pseudomonas aeruginosa was studied in a rabbit model simulating a closed-space infection in a locally neutropenic...Full Text Available

KoreaScience (Korea)

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British Library Electronic Table of Contents (United Kingdom)

The investigations were conducted at the Center of Biotechnology and Molecular Diagnostics of the All-Russian Animal Husbandry Research Institute, where a number of valuable transgenic animals (rabbits, sheep, and pigs) have been produced over the course of 20 years. The article presents the blood indices of control and transgenic rabbits with an integrated insulin gene.

UK PubMed Central (United Kingdom)

PURPOSETo examine the mechanisms of ischemic preconditioning (IPC) related to the opening of mitochondrial KATP (mKATP) channels in the retina.Full Text Available

UK PubMed Central (United Kingdom)

Aims: This study sought to elucidate the effects of timolol and dorzolamide on intraocular pressure (IOP) and retinal ganglion cell (RGC) death in an experimental...Full Text Available

UK PubMed Central (United Kingdom)

Retinal pigment epithelial (RPE) cells, derived from the neuroectoderm, biosynthesize the novel lipid mediator neuroprotectin D1 (NPD1) from docosahexaenoic acid (DHA) in response to oxidative...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The authors report that the replacement of Leu-93 in bacteriorhodopsin by Ala (L93A) or Thr (L93T) slows down the photocycle by approximately 100-fold relative to wild-type bacteriorhodopsin. Time-resolved visible absorption spectroscopy and resonance Raman experiments, respectively, show the presence of long-lived O-like and N-like intermediates in the photocycles of the above mutants. We infer the existence of an equilibrium between the N and O intermediates in the photocycles of these mutants. The L93A and L93T mutants exhibit normal proton pumping under continuous illumination, suggesting that the decay of the N and/or O intermediate, and consequently, proton translocation, can be accelerated by the absorption of a second photon. Since the 13-cis----all-trans reisomerization of retinal is completed during the decay of the N and O intermediates, they conclude that the interaction of Leu-93 with retinal is important in this phase of the ...

International Nuclear Information System (INIS)

... ammonium compounds antigen-antibody reactions hemoglobin inhibition

British Library Electronic Table of Contents (United Kingdom)

To analyze the effect of containment spray on gas mixing and depressurization, two experiments (ST3_1 and ST3_2) were performed with two interconnected vessels. These experiments were conducted in the frame of the OECD/SETH-2 project using the PANDA facility. The vessels were preconditioned such that a helium-rich layer is formed in the upper section of the first vessel, henceforth referred to as Vessel-1. In the case of the first experiment (ST3_1), the remaining volume of Vessel-1 and the entirety of the second vessel, Vessel-2, were filled with pure steam. For ST3_2, the second experiment presented here, pure steam was replaced with a steam-air mixture instead. Water was injected from the top of Vessel-1 with a spray nozzle projecting downwards. Transient behavior of system pressure, as...

UK PubMed Central (United Kingdom)

Eight rabbits and 24 guinea-pigs were exposed to a silica dust cloud of about 40,000 pp./ml. (0·3-3·0 μ) and killed at four-weekly intervals up to 30 weeks. The guinea-pigs showed...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

This study assesses the feasibility of removing the FFTF reactor vessel from its current location in the reactor cavity inside the Containment vessel to a transporter for relocation to a burial pit in the 200 Area.

UK PubMed Central (United Kingdom)

Sensory rhodopsins (SRs) belong to a subfamily of heptahelical transmembrane proteins containing a retinal chromophore. These photoreceptors mediate the cascade of vision in animal eyes and phototaxis...Full Text Available

UK PubMed Central (United Kingdom)

ATP-binding cassette transporters (ABC transporters) utilize the energy of ATP hydrolysis to translocate an unusually diverse set of substrates across cellular membranes. ABCA4, also known as...Full Text Available

UK PubMed Central (United Kingdom)

PurposeNocturnal rhythms of gene expression in the retina are known to be both darkness- and circadian clock-dependent, but their role and cellular location are not well defined....Full Text Available

UK PubMed Central (United Kingdom)

Background:The purpose of the study was to evaluate vitreoretinal interface (VRI) alteration with a short-wavelength scanning laser ophthalmoscope (swSLO), the Nidek F-10, and compare...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

The retinal degeneration 10 (rd10) mouse is a well-characterized model of autosomal recessive retinitis pigmentosa (RP), which carries a spontaneous mutation in the ? subunit of rod cGMP-phosphodiesterase (PDE?). Rd10 mouse exhibits photoreceptor dysfunction and rapid rod photoreceptor degeneration followed by cone degeneration and remodeling of the inner retina. Here, we evaluate whether gene replacement using the fast-acting tyrosine-capsid mutant AAV8 (Y733F) can provide long-term therapy in this model. AAV8 (Y733F)-smCBA-PDE? was subretinally delivered to postnatal day 14 (P14) rd10 mice in one eye only. Six months after injection, spectral domain optical coherence tomography (SD-OCT), electroretinogram (ERG), optomotor behavior tests, and immunohistochemistry showed tha...

UK PubMed Central (United Kingdom)

PurposeTo investigate the effects of laser photocoagulation (LP)-induced ocular hypertension (OHT) on the survival and retrograde axonal transport of retinal ganglion cells (RGC),...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundMost retinal ganglion cells (RGCs) convey contrast and motion information to visual brain centers. Approximately 2% of RGCs are intrinsically photosensitive (ipRGCs), express...Full Text Available

UK PubMed Central (United Kingdom)

Mice harboring a null mutation in Abca4/Abcr serve as a model of autosomal recessive Stargardt disease. Consistent with the human retinal disorder, deficiency...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

PurposeWe objectively quantified the gain in urethral diameter and the effect of stenting after tubularized incised plate urethroplasty in a rabbit hypospadias model. Materials and MethodsWe created a hypospadias model in 12 New Zealand white male rabbits by excising the ventral urethra. A 3 cm tattoo line was made longitudinally in the dorsal urethral plate midline. Two weeks later a 2 cm relaxing incision was made in the middle part of the tattooed line. The stretched incision width between the tattooed edges was measured, followed by urethral plate tubularization. Six rabbits were stented and 6 were nonstented. Two weeks later the animals were sacrificed and the distance separating the tattoo was measured at the midpoint of the tattooed line. Transverse sections at this point were exami...

International Nuclear Information System (INIS)

Experiments have been reported previously in which lead-212 ions with lead carrier were instilled into the lungs of anaesthetised rabbits. Experiments were also reported in which bismuth-207 chloride was instilled into rabbit lung. To check that the chloride compound was cleared in the same way as ions instilled in isolation, lead-203 chloride has been instilled in three rabbits. Measurements of absorption of ionic lead have been repeated using the radon-222 daughter, lead-214. Rates of clearance from the lung of "2"0"3Pb as the chloride and "2"1"2Pb ions are compared, and retention functions are derived. Clearance from the lung of "2"1"4Pb ions is also shown, and retention functions are derived. (U.K.).

International Nuclear Information System (INIS)

Short communication.

UK PubMed Central (United Kingdom)

A comparative and quantitative study of the tissue distribution of brain-thymus shared antigens was carried out using rabbit antisera to rat, dog and human brain homogenates, assayed on rat, dog and...Full Text Available

UK PubMed Central (United Kingdom)

1. The metabolism of (±)-cis-1-, (±)-trans-1-, (±)-cis-2- and (±)-trans-2-decalone in the rabbit...Full Text Available

UK PubMed Central (United Kingdom)

The pharmacological effects of a series of fatty acid-choline esters have been studied on the isolated rabbit heart, the isolated guinea-pig ileum and the rat stomach. The effect changed with increasing...Full Text Available

UK PubMed Central (United Kingdom)

Hyaluronan (HA) is important for joint cavitation, lubrication, volume regulation and synovial fluid drainage but little is known about the regulation of joint HA synthesis/secretion in vivo....Full Text Available

UK PubMed Central (United Kingdom)

Naturally occurring, double-stranded RNA (ds-RNA)) was immunogenic when injected into mice, rats, guinea-pigs, rabbits, dogs and baboons. The response to native material administered intravenously (i.v.)...Full Text Available

UK PubMed Central (United Kingdom)

Antibodies of the IgM type present in rabbit anti-epiglycanin antiserum were purified by (NH4)2SO4 precipitation and by ion-exchange, affinity and gel-filtration chromatography. After papain treatment...Full Text Available

UK PubMed Central (United Kingdom)

Orientation and movement relies on both visual and vestibular information mapped in separate coordinate systems. Here, we examine how coordinate systems interact to guide eye movements of rabbits....Full Text Available

Science.gov (United States)

1. Gamma globulin metabolism and distribution were studied employing rabbit gamma globulin (RGG)I(131) 24 times in 13 control rabbits. Similar studies were performed before and during the ananmestic response in 4 rabbits previously sensitized with a polyvalent pneumococcal vaccine. 2. During the ananmestic response, gamma-globulin levels increased from 1.0 to 6.0 gm/100 ml, and the gamma-globulin pool increased from 0.7 to 4.7 gm/kg. There was no change in the intravascular-extravascular partition of gamma globulin. 3. Gamma globulin degradation increased from 0.06 to 0.33 gm/kg/day during the 28 days of the immunization period while gamma globulin synthesis increased even further to average 0.47 gm/kg/day. Following the attainment of elevated gamma globulin levels the fractional rate of RGG-I(131) turnover increased from 8.0 to 12.5 per cent/day. 4. No differences were noted in the metabolism of homologous or autologous ...

UK PubMed Central (United Kingdom)

Drugs used for the inhibition of DNA viruses, such as iododeoxyuridine, adenine arabinoside, or trifluorothymidine, are not biochemically selective in their action and also interfere with normal cellular...Full Text Available

UK PubMed Central (United Kingdom)

In vivo, mammalian lenses have the capacity to effect fully reversible changes in shape, and possibly volume, during the accommodation process. Isolated lenses also change shape...Full Text Available

UK PubMed Central (United Kingdom)

Tooth enamel biomineralization is mediated by enamel proteins synthesized by ameloblast cells. Two classes of proteins have been described: enamelins and amelogenins. In lower vertebrates the absence...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The placental transfer of a single intravenous injection of 14C-hexoprenaline was studied in eight pregnant New Zealand white rabbits. Maternal and fetal blood was sampled intermittently for 60 minutes after the injection. An initial rapid decrease in the levels of 14C-hexoprenaline in maternal blood was followed by a second slower phase, whereas fetal levels remained insignificant. The conclusion, therefore, is that the rapid improvement in fetal heart rate after the administration of a single maternal intravenous injection of hexoprenaline in the treatment of fetal distress is due to the action on the uterus and/or on maternal cardiovascular function, and not to direct stimulation of the fetus.

International Nuclear Information System (INIS)

This report describes a neutron fluence assessment performed for the Kori Unit 3 pressure vessel beltline region based on the guidance specified in Regulatory Guide 1.190. In this assessment, maximum fast neutron exposures expressed in terms of fast neutron fluence (E>1 MeV) and iron atom displacements (dpa) were established for the beltline region of the pressure vessel. After Cycle 16 of reactor operation, 2nd Ex-Vessel Neutron Dosimetry Program was instituted at Kori Unit 3 to provide continuous monitoring of the beltline region of the reactor vessel. The use of the Ex-Vessel Neutron Dosimetry Program coupled with available surveillance capsule measurements provides a plant specific data base that enables the evaluation of the vessel exposure and the uncertainty associated with that exposure over the service life of the unit. Ex-Vessel ...

British Library Electronic Table of Contents (United Kingdom)

Elevated nuclear factor kappa B (NF-@kB) activity and interleukin-6 (IL-6) secretion participates in the pathology of several age and inflammatory-related diseases, including age-related macular degeneration (AMD), in which retinal pigment epithelial cells are the key target. Recent findings reveal that heat shock protein 70 (Hsp70) may affect regulation of NF-@kB. In the current study, effects of Hsp70 expression on NF-@kB RelA/p65 activity were evaluated in human retinal pigment epithelial cells (ARPE-19) by using celastrol, a novel anti-inflammatory compound. Anti-inflammatory properties of celastrol were determined by measuring expression levels of IL-6 and endogenous NF-@kB levels during lipopolysaccharide (LPS) exposure by using enzyme-linked immunosorbent assays (ELISA). Cell viabil...

British Library Electronic Table of Contents (United Kingdom)

Purpose Ultraviolet-B (UV-B) radiation can cause phototoxic macular injuries in young people who have been sunbathing but not sungazing and in welders. Welders have a reportedly increased risk of uveal melanoma. We analyze phakic and pseudophakic risks for solar and welding arc UV-B exposure. Design Optical radiation measurement, analysis, and perspective. Methods Spectral transmittances were measured for UV-transmitting, UV-blocking, and blue-blocking intraocular lenses (IOLs). The photoprotective performances of crystalline and intraocular lenses were analyzed using relevant epidemiologic and laboratory data and action spectra for acute retinal phototoxicity and melanoma photocarcinogenesis. Results Crystalline lens UV-B retinal protection is deficient in children and young adults, incre...

British Library Electronic Table of Contents (United Kingdom)

To test the hypothesis that transduction of the channelrhodopsin-2 (ChR2) gene, a microbial-type rhodopsin gene, into retinal ganglion cells of genetically blind rats will restore functional vision, we recorded visually evoked potentials and tested the experimental rats for the presence of optomotor responses. The N-terminal fragment of the ChR2 gene was fused to the fluorescent protein Venus and inserted into an adeno-associated virus to make AAV2-ChR2V. AAV2-ChR2V was injected intravitreally into the eyes of 6-month-old dystrophic RCS (rdy/rdy) rats. Visual function was evaluated six weeks after the injection by recording visually evoked potentials (VEPs) and testing optomotor responses. The expression of ChR2V in the retina was investigated histologically. We found that VEPs could not b...

Energy Technology Data Exchange (ETDEWEB)

A reflux condensing start-up system includes a steam generator, a start-up vessel connected parallel to the steam generator, a main steam line connecting steam outlets of the steam generator and start-up vessel to a steam turbine, a condenser connected to an outlet of the turbine and a feedwater return line connected between the condenser and inlets of the steam generator and start-up vessel. The start-up vessel has one or more heaters at the bottom thereof for heating feedwater which is supplied over a start-up line to the start-up vessel. Steam is thus generated to pressurize the steam generator before the steam generator is supplied with a heat transfer medium, for example liquid sodium, in the case of a liquid metal fast breeder reactor. The start-up vessel includes upper and lower bulbs with a smaller diameter mid-section to act as water and steam ...

Science.gov (United States)

Nearly a decade after the small boat attacks against the USS Cole (in 2000) and M/V Limburg (in 2002) in Yemen, small vessels continue to pose a security threat. In part, this is due to the ease of camouflage and the high frequency of small vessels operat...

UK PubMed Central (United Kingdom)

A technique is described for displaying distinct tissue layers of large blood vessel walls as well as measuring their mechanical strain. The technique is based on deuterium double-quantum-filtered (DQF)...Full Text Available

International Nuclear Information System (INIS)

In this paper, an investigation was performed on a failure pressure vessel, which was as an anti-freezing heater for General Gas Storage and Distribution (SGZ) system. Evident and serious deformation was observed on the body of the vessel. A metallurgical investigation was conducted to establish the mechanism and cause of deformation of the anti-freezing heater at Daya Bay PWR station in China. The investigation, which was performed on specimens cut from the most serious area deformed of the vessel, included macroscopic examination and microscopy examination. The results of the examinations showed that some lamellar pearlite in the microstructure were already spheroidized. It was confirmed that the vessel was operated at high temperature. Stress analysis for the vessel was conducted. And it was confirmed that, in ideal conditions, the vessel would be deformed at ...

International Nuclear Information System (INIS)

Generally, Hardening and irradiated brominating phenomena are occurred in the reactor vessel under operation conditions by atomic cavities and creation of impurity atoms which are led by high fast neutron flux. To assure the mechanical integrity of pressure vessel until the end of power plant life after monitoring the sample specimens on the vessel inside, a series of tests is performed over the retrieved surveillance capsule to examine the changes according to the plant operation in accordance with regulations. Monitoring surveillance capsules attached to neutron shield wall of outer core are consists of impact sample, tensile sample and temperature monitor

Science.gov (United States)

PMID:9226309

Energy Technology Data Exchange (ETDEWEB)

To assess the technical feasibility of a newly designed stent-like electrode in rabbits. A stent-like electrode was knitted from a single thread of nitinol wire and interconnected to a generator using similar wire. In order to gauge the extent of radiofrequency ablation (RFA), we measured the depth of the ablated area in cow liver using a combination of 180-sec time intervals and 20- watt power increments. For data processing, Cox regression analysis was used. RFA was also applied to the small intestine of rabbits using this stent-like electrode under six different sets of conditions: 10 watts for 1 min, 10 watts for 2 mins, 20 watts for 1 min, 20 watts for 2 mins, 30 watts for 1 min, and 30 watts for 2 mins. To determine the gross and microscopic findings, six animals were sacrificed immediately after the procedure and the results obtained under the different sets of conditions were correlated. Eight rabbits were monitored ...

International Nuclear Information System (INIS)

A fluidic pump comprises a two-diode pump having a first displacement vessel, a third diode connected to receive output from the two-diode pump through a delivery line and discharge to an outlet, and a second displacement vessel connected to the delivery line. There is a feed tank at a greater height than the two-diode pump, and a drive unit for alternately pressurising and venting the first and second displacement vessels. The drive pressure required to operate the pump can be of the order of half that for a single stage 2-diode pump. (author).

UK PubMed Central (United Kingdom)

The aim of this study is to determine the effects of silver nanoparticles (Ag-NP) on vascular endothelial growth factor (VEGF)-and interleukin-1 beta (IL-1β)-induced vascular permeability, and...Full Text Available

UK PubMed Central (United Kingdom)

The immunolocalization of the low density lipoprotein receptor-related protein 1 (LRP1) and its ligand alpha 2-Macroglobulin (α₂M) was examined in tissues from human donor...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Glycosaminoglycans synthesized by cultured rabbit smooth muscle cells were isolated after incorporation of (/sup 3/H)-glucosamine into glycosaminoglycans in the presence or absence of 10% fetal bovine serum. Glycosaminoglycans were quantitated by two-dimensional electrophoresis after proteolytic digestion of the cell layers and media. The results show that the presence of serum has no effect on the chondroitin sulfate, heparan sulfate and dermatan sulfate content of the cell layers. The incorporation of (/sup 3/H)-glucosamine into hyaluronic acid of the cell layers was three times higher in the presence of serum. In the medium , the quantity of hyaluronic was two times higher in the presence of serum while the other glycosaminoglycans remained unchanged. The incorporation of (/sup 3/H)-glucosamine into hyaluronic acid was unaffected by the presence of serum. Specific proteoglycans were isolated from medium after with (/sup 35/S)-sulfate and (/sup 3/H)-serine by ...

International Nuclear Information System (INIS)

Purpose: The lifelong persistence of foreign bodies within the arteries may contribute to restenosis. Thus,biodegradable devices might decrease recurrence rates. Methods: Eleven polyhydroxybutyrate biodegradable stents and 13 tantalum stents were implanted into the iliac arteries of New Zealand white rabbits for up to 30 weeks. After killing the animals,the specimens were harvested, fixed in formalin, processed in paraffin,and stained. Results: Polyhydroxybutyrate instigated intense inflammatory and proliferative reactions with an increase in collagen (2.4- to 8-fold vs native segments), thrombosis and in-stentlumen narrowing (375.5-606.6 mm vs 655.6 #+-# 268.8 mm in native segments). The elastic membranes were destroyed in all specimens. The tantalum stents increased the in-stent lumen progressively (769.7 #+-# 366.6 mm vs 1309.9 #+-# 695.3 mm),penetrated the external elastic membrane, and increased mural collagen content (6- to 8.6-fold vs native segments). ...

Energy Technology Data Exchange (ETDEWEB)

The authors study technological safety of installing a water spray pressure vessel between electrostatic deduster and coal sludge ducts. These sprays are in use elsewhere for steam generator ash removal. Dust ignition and explosion tests were carried out to examine flame and pressure wave propagation through the vessel into ducts. Water jet diameter, amount of water sprayed and coal dust removed were varied. Pressure waves exceeded 250 Pa. Test results show the vessel to be suitable for installation in briquetting plants due to its flame and explosion barrier effect and extermination of smoldering dust fires. The only disadvantage of the vessel is seen as its water and electric power consumption: about 8 m/sup 3//h of water and 1.5 kW/h of power per vessel serving dedusters of a 2,200 m/sup 2/ rotary brown coal dryer. (MOS).

British Library Electronic Table of Contents (United Kingdom)

The purpose of this study was to investigate whether hydroxyapatite (HAp) coating could induce polyethylene terephthalate (PET) artificial ligament graft osseointegration in the bone tunnel. Twenty-four New Zealand white rabbits underwent artificial ligament graft transplantation in bilateral proximal tibia tunnels. One limb was implanted with HAp-coated PET graft, and the contralateral limb was implanted with non-HAp-coated PET graft as control. The rabbits were randomly sacrificed at four and eight?weeks after surgery. The loads to failure of the experimental group at eight?weeks were significantly higher than those of the control group (p?=?0.0057). Histologically, application of HAp coating induced new bone formation between graft and bone at eight?weeks compared with the controls. Rea...

British Library Electronic Table of Contents (United Kingdom)

Aim: This study was performed: 1) to assess the relationship between blood flow velocity in the internal carotid artery (CBFICA) and pial artery pulsation (cc-TQ) and 2) to evaluate flow-induced changes in pial artery compliance. Methods: Experiments were performed on 10 crossbred male rabbits. Heart rate (HR), blood pressure (BP), left ventricle ejection fraction (LVEF), CBFICA, the systolic-diastolic blood volume fraction in the brain circulation (CBFSDF) and cc-TQ were recorded after glucagon and acetazolamide administration. cc-TQ was measured with near-infrared transillumination back scattering sounding (NIR-T/BSS), LVEF and CBFSDF with gated scintigraphy and BP and CBFICA with electromagnetic pressure and flow transducers, respectively. Doses of drugs were chosen to exert a haemodyna...

Energy Technology Data Exchange (ETDEWEB)

This patent describes a nuclear system comprising a containment airspace in which a nuclear reactor pressure vessel is disposed there being a reactor core within the pressure vessel. It comprises a heat exchanger elevated a distance above the pressure vessel; a pool of water surrounding the heat exchanger; means for venting the pool of water to an environment outside the containment; a heat exchanger entry conduit within the containment, the entry conduit having an open lower end communicating with the containment space, and an upper end connected to the heat exchanger, water-containing heated fluid present in the containment airspace incident a pressure vessel loss of coolant event entering and flowing through the entry conduit into the heat exchanger for cooling the fluid to convert water vapor therein to a condensate and separate non-condensable gasses therefrom; a gravity driven cooling water ...

Wastenet

... The dawn of Bio-Mecha and a Biomechanical Revolution May 31 2011: Hi Julian, Yes, but i dont think we would ... The dawn of Bio-Mecha and a Biomechanical Revolution May 31 2011: A BBC Documentary: All Watched Over by Machines of Loving ... The dawn of Bio-Mecha and a Biomechanical Revolution May 17 2011: Ed Boyden: A light switch for neurons is an amazing ... The dawn of Bio-Mecha and a Biomechanical Revolution May 16 2011: Thank you Meher Like Spring Rabbit, its a great contribution....

UK PubMed Central (United Kingdom)

BackgroundHerpes simplex virus type-1 (HSV-1) infections can cause a number of diseases ranging from simple cold sores to dangerous keratitis and lethal encephalitis. The interaction...Full Text Available

International Nuclear Information System (INIS)

An analogue of hGH isolated from plerocercoids of the tapeworm Spirometra mansonoides displaces ["1"2"5I]hGH from its receptors in rabbit, rat, and hamster liver membranes. Biologically, plerocercoid growth factor (PGF) is more similar to hGH than to other mammalian GH's but has not been shown to bond human cells. Receptors specific for hGH have been described on cultured human lymphocytes (IM-9). In this study, the authors compared the binding of PGF and hGH in IM-9 cells and in rabbit hepatic membranes. IM-9 lymphocytes (12 x 10"6 cells/tube) were incubated with ["1"2"5I]hGH and increasing concentrations of hGH (ng/ml) or PGF (serial dilutions) for 90 min at 30"0 C. Specific binding (B_0 - NSB) was determined for each dose of hGH or PGF and the binding curves were analyzed by logit-log regression. The results show that PGF displaced ["1"2"5I]hGH from human cells in a dose dependent manner (r = 0.98). Based on the IM-9 assay, 1 ml of the PGF ...

Energy Technology Data Exchange (ETDEWEB)

Researchers at Lawrence Livermore National Laboratory are developing high-performance explosive firing vessels to contain (one time) explosive detonations that contain toxic metals and hazardous gases. The filament-wound polymer composite vessels are designed to contain up to 80 lb (TNT equivalent) explosive in a 2-meter sphere without leakage. So far, two half-scale (1-meter diameter) vessels have been tested; one up to 150% of the design explosive limit. Peak dynamic pressures in excess of 280 MPa (40 Ksi) in the vessel were calculated and measured. Results indicated that there was a small amount of gas and particle leakage past the first two of the seven o-ring seals. However, the remaining five seals prevented any transient leakage of the toxic gases and particulates out of the vessel. These results were later confirmed by visual inspection and particulate analysis of swipes ...

International Nuclear Information System (INIS)

The Melt Vessel Interaction (MVI) project is concerned with the consequences of the interactions that a core melt, generated during a postulated severe accident in a light water reactor, may have with the pressure vessel. In particular, the issues concerned with the failure of the vessel bottom head are the focus of the research. The specific objectives of the project are to obtain data and develop validated models, which could be applied to prototypic plants, and accident conditions, for resolution of issues related to the melt vessel interactions. The project work has been performed by nine partners having varied responsibility. The work included a large number of experiments, with simulant materials, whose observations and results are employed, respectively, to understand the physical mechanisms and to develop validated models. Applications to the prototypic geometry and conditions have also been ...

International Nuclear Information System (INIS)

Debris coolability in the lower plenum of the reactor pressure vessel is an important factor for evaluation of debris in-vessel retention. The debris coolability analysis module is developed for the accurate prediction of the safety margin of the present reactor vessels in a severe accident. The module calculates debris spreading and cooling through melting and solidification in combination with a temperature distribution and failure evaluation of the vessel wall. Debris spreading is solved by the explicit method on a quasi-three-dimensional scheme and debris coolability is solved on the basis of natural convection analysis. The calculation for spreading is compared with a water spreading experiment on the floor and the calculation for coolability is compared with a n-octadecane melting experiment in a rectangular vessel. The comparisons show capabilities for predictions of ...

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A prototype hydride storage bed, using LaNi{sub 4.25}Al{sub 0.75} as the storage material, was fitted with strain gages to measure strains occurring in the stainless steel bed vessel caused by expansion of the storage powder upon uptake of hydrogen. The strain remained low in the bed as hydrogen was added, up to a bed loading of about 0.5 hydrogen to metal atom ratio (H/M). The strain then increased with increasing hydrogen loading ({approximately} 0.8 H/M). Different locations exhibited greatly different levels of maximum strain. In no case was the design stress of the vessel exceeded.

Energy Technology Data Exchange (ETDEWEB)

The recent definition of a postulated thermal shock accident followed promptly by system repressurization, termed an overcooling or pressurized thermal shock accident, has set a large analysis and research effort into motion. The essential elements are concerned with defining the accident transients, evaluating the instrumentation and controls that cause the postulated accidents, and evaluating the metallurgical and structural mechanics aspects of the reactor vessel with respect to its failure potential. This paper poses the question faced by the Nuclear Regulatory Commission (NRC) for the vessel steel embrittlement, annealing, and surveillance dosimetry facets of this postulated accident and provides information on our plans for study of this problem as well as current status.

Energy Technology Data Exchange (ETDEWEB)

The potential retinal hazard of dental visible-light photopolymerization units and the efficacy of protective lenses for reducing the potential hazards were assessed. The spectral radiance profiles of 11 visible-light photopolymerization units were measured; and the results were then weighted according to the American Conference of Governmental Industrial Hygienists (ACGIH) Blue Light and Thermal Hazard Functions. The results indicate that there are no thermal hazards to the retina even for the worst case condition. None of the blue-light hazard maximum permissible exposure times is short enough to be of concern unless the individual operator chooses to focus on the light source for an extended period. Those individuals who elect to stare at the light during curing procedures should consider the purchase of protective lenses. The special transmission profiles of 16 protective lenses were measured and new permissible exposure limits calculated for each lens/unit ...

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My assignment on the SP-100 Vacuum Vessel Vacuum System Team was to perform a transient pump down analysis for the vacuum vessel that will house the SP-100 reactor during testing. Pump down time was calculated for air and helium. For all cases the proposed vacuum system will be able to pump down the vessel within the required time. The use of a larger rotary piston pump (DUO250) improves the pump down time by 35 minutes and therefore should be considered. The 6-inch duct for the roughing line is optimal, however, because all cases are well below the 24 hour time frame, the 4-inch duct is sufficient. The use of the single turbomolecular pump during pump down is sufficient. A pump down with helium in the vessel and a helium inleakage delays the time to achieve the base pressure marginally and is acceptable.

UK PubMed Central (United Kingdom)

In order to investigate the role of mononuclear cells in infiltrates during the initial stages of atherogenesis, the authors have studied by immunohistochemical methods the aortas and coronary vessels...Full Text Available

Science.gov (United States)

A full-scale model of a rigid sectorial ring and a set of bellows which was covered with a temperature control layer and a coolant supply equipment was constructed to verify the adequacy of the heating and cooling system designed for JT-60. To cool and heat it effectively and to decrease the temperature differences among the various parts in the vacuum vessel, heater units and cooling pipes were located on the surface of the ring. The temperature control layer is to heat the vessel to 500/degree/sub //C within 70 hours and to maintain it at the temperature for 48 hours for simulating the state of bakeout. Subsequently the vessel is cooled down within about the same time as in heating. Prior to the series of tests, numerical analyses were performed to predict the cooling and heating efficiencies on the model and to examine the method of the temperature regulation.

Science.gov (United States)

... 2008. Characterizing the relative contributions of large vessels to total ocean noise fields: a case study using the Gerry E. Studds Stellwagen Bank ...

Science.gov (United States)

... Characterizing the Relative Contributions of Large Vessels to Total Ocean Noise Fields: A Case Study Using the Gerry E. ... ...

International Nuclear Information System (INIS)

Feb 2006 p. 80-84 Japan Mizuno, R. Matsuda, F. Japan Power Engineering

British Library Electronic Table of Contents (United Kingdom)

VWS Westgarth, a subsidiary of Veolia Water Solutions & Technologies (VWS), has been awarded a multi-million dollar contract by Daewoo Shipbuilding & Marine Engineering Co (DSME), under which it will design, supply and deliver two treatment units for use on a floating production storage and offloading (FPSO) vessel.

International Nuclear Information System (INIS)

In order to evacuate the residual power in a nuclear reactor, a thermal valve system is presented for the modification of the heat exchange conditions at the pool exchanger level, which avoids the use of mechanical valves on the pipes. The system involves a vessel containing the exchanger, with openings at the upper end of the vessel and means for feeding the fluid at the lower end, and means for controlling the opening width.

Energy Technology Data Exchange (ETDEWEB)

On March 28, 1979, the Pennsylvania Three Mile Island nuclear power plant Unit 2 (TMI-2) suffered a partial fuel-melt accident. During this accident, over 20,000 lb of molten fuel flowed through holes melted through the baffle plates and through the lower-core support assembly (LCSA). The molten fuel subsequently resolidified in the bottom of the reactor vessel. The lower-core support assembly of the TMI-2 reactor was not structurally damaged during the accident. In order to permit defueling of that region of the core, the LCSA was cut to permit access. A five-axis teleoperator was developed to deliver plasma arc cutting, rotary grinding and abrasive waterjet cutting of end effectors to the LCSA. Complex geometry sectioning was completed in a mock-up facility at chemistry and pressure conditions simulating those of the vessel, prior to actual in-vessel operations. In-vessel activities began in early May ...

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As need for development of marginal and deepwater oil fields grows, demand increases for floating production vessels (FPVs) such as floating production, storage and offloading (FPSO) units; spread-moored production semi-submersibles; and turret-moored production vessels. The FPV may be purpose-built; or an existing vessel such as an exploration drilling semi-sub or ship-shape vessel may be modified to suit the purpose. In either case, requirements for tensioning systems for the mooring lines on the FPV are quite unique, and are not without the potential for problems when traditional chain windlasses or wire rope systems are employed. This two-part article discusses the range of available technologies and systems for tensioning mooring lines on FPVs. It examines problems of size, weight and safety associated with some available designs; and it considers in detail a specific family of new units. Part 1, ...

Energy Technology Data Exchange (ETDEWEB)

The Terra Nova offshore oil project is described, with emphasis on the construction of the Terra Nova Floating Production Storage and Offloading (FPSO) vessel, the first such vessel constructed for the harsh environment of the North Atlantic off Newfoundland, the site of an oil field that is expected to produce 125,000 to 150,000 barrels of oil per day starting in 2001. The vessel has a double-hull, made of 3,000 tons of reinforced steel to protect it from ice in the form of massive icebergs or crusty 'packs'. The vessel has the world's largest quick release turret, meaning that the vessel can be quickly disconnected from its turret and mooring in the event of an encroaching iceberg, and then reconnected in an environmentally sound way. Apart from its extremely rugged construction, protecting the FPSO vessel against icebergs is ...

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Hyaluronan is an important constituent of the extracellular matrix in skin, and recent studies suggest that there is a pool of easily removable (free) hyaluronan drained by lymph. The removal rate of free hyaluronan in skin was measured from the elimination of ({sup 3}H)hyaluronan, injected subcutaneously in 13 rabbits. The removal of radioactivity was determined from appearance of {sup 3}H in plasma. During the first 24 h after injection, 10-87% of the tracer entered blood, less in injectates with high concentrations of hyaluronan. The removal was monoexponential with a half-life of 0.5-1 day when concentration of hyaluronan was 5 mg/ml or less. When hyaluronan concentration was 10 mg/ml or higher, the removal was slow for about 24 h and then became similar to that in experiments with low hyaluronan concentration. Free hyaluronan at physiological concentrations is thus turned over with the same rate as serum albumin, supporting the concept that hyaluronan is ...

Energy Technology Data Exchange (ETDEWEB)

A new /sup 99m/Tc-phosphine-isocyanide complex with the general structure (/sup 99m/Tc (DEPE)/sub 2/(CNR)/sub 2/)/sup +/ has been synthesised and tested in animals and one human. In three animal species (rat, rabbit, dog), the complex is an efficient myocardial imaging agent, while in humans it remains in the blood pool. The complex is 100% protein bound in animals and humans, but whereas in humans it is attached to a 51.5 kdalton protein (probably prealbumin), in rabbits it appears to be bound to a larger macromolecule (M.W.>100 kdalton). The efficiency of the complex for blood pool labelling was tested in a human volunteer and compared with the standard in vivo red cell labelling technique with stannous pyrophosphate. A satisfactory radionuclide angiogram could be performed with less than 370 MBq of the complex. The count rate for the complex (cps/MBq) was 15% higher than that obtained with the labelled red cells and the absence of splenic ...

Energy Technology Data Exchange (ETDEWEB)

Central penetrating excisional wounds were made in the corneas of 12 rabbits and 10 trout. The scar tissue and the surrounding cornea were compared using a new method for assessing inorganic elements in the cornea: the scanning electron microscopy and energy dispersive analysis of x-ray (EDAX). Semiquantitative determination of inorganic elements within the range of atomic numbers 9-93 in the periodic system was performed, comparing the relative concentration of those elements in the scar tissue to the surrounding cornea. Results showed that calcium was the only element higher in the healing wound than in the surrounding cornea.

Energy Technology Data Exchange (ETDEWEB)

We irradiated proton beams on the ears of rabbits and the Harding-Passey mouse melanoma and observed their morphological change. We used 52 MeV proton beams from the INS-FM cyclotron. We adjusted the energy of the proton beams to be at the plateau part of the Bragg curve, at the half-way point of the Bragg peak, and at the Bragg peak. The amount of radiation was 5000rad in each case. The Harding-Passey mouse melanoma was transplanted into the subcutan of a three week old mouse. In this experiment, we used tumors, the diameter of which grew up to 1.5-2cm in 2-3 weeks after the transplantation. Using the jroscope, we observed both lightly and severely damaged cells. Using proton irradiation with the Bragg peak located at depth of 1mm in the rabbit's ears, we studied the change in the tissue. Irradiated epidermis fell off and was eroded because of radiation damage, but the rear surface of the rabbit's ears ...

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Reactor pressure vessel (RPV) steels are subjected to neutron irradiation at a temperature of about 290 deg C. This radiation exposure alters the mechanical properties, leading to a shift of the brittle-to-ductile transition temperature toward higher temperatures and to a diminution of the rupture energy as determined by Charpy V-notch tests. This radiation embrittlement is one of the important aging factors of nuclear power plants. U.S. NRC recommended the basic requirements for the determination of the pressure vessel fluence by regulatory guide DG-1025 in order to reduce the uncertainty in the determination of neutron fluence calculation and measurements. The determination of the pressure vessel fluence is based on both calculations and measurements. The fluence prediction is made with a calculation and the measurements are used to qualify the calculational methodology. Because of the importance and the difficulty of ...

British Library Electronic Table of Contents (United Kingdom)

On ships, tankers and similar vessels structural defects such as cracks and corrosion damage are typically repaired by welding. However, welding is unwanted hotwork on floating offshore units (FOUs) such as floating, production, storage and offloading (FPSO) and floating, storage and offloading (FSO) vessels because it requires shutdown of parts of the vessel thus resulting in expensive production delays. Bonded fibre composite material patch repairs can be used as an alternative to overcome the hazards of hotwork associated with welding. The patches are bonded over the defect and the integrity of the original structure is hence restored. The patch repair technology can also be utilised to provide upgrades, such as life extensions and higher design requirements. A recommended practice (RP)...

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Two patients who developed large intracranial vessel occlusion after standard radiation therapy for brain tumor are described. This form of vascular occlusion is usually seen in patients who have previously been treated by radiotherapy for intracranial tumor who then develop a relatively acute change in neurologic status. Histology of the lesion mimics accelerated focal arteriosclerosis. The clinical and radiographic manifestations of one case were highly atypical. The vasculopathy became evident shortly after termination of radiation therapy for a fourth ventricular ependymoma, and the angiographic picture stimulated a diffuse arteritis. The second patient was more typical, with clinical symptoms developing 12 years after radiation therapy for an oligodendroglioma. Occlusion of a proximal vessel that had been included in the radiation port was demonstrated radiographically and confirmed by pathologic examination. The clinical, angiographic, ...

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The measurement of level in the liquid nitrogen vessel has been carried out by the weight conversion method using weigher or by putting directly a stick in the vessel. On a large CE tank, the pressure difference was read by manometer. These methods can not be used when the vessel does not put on the weigher or the pipe for manometer is stopped. We noticed the interaction between radiation ({gamma}-ray) and substance and applied it to determine the liquid nitrogen level. The results proved it the easy method for measurement of the level in the large CE tank. Cesium 137 ({gamma}-ray energy: 662 keV) was used as the radiation source. {gamma}-ray transmission dose was determined by GM survey meter. The liquid nitrogen level could be determined by using the change of the transmission dose with amount of liquid nitrogen. (S.Y.)

Energy Technology Data Exchange (ETDEWEB)

A pipeless batch plant is a batch processing production system using mobile vessels. The plant performances depend on both hardware of equipment and software of operation. So the plant includes many design factors such as number of vessels, stations and AGVS, layout of stations, vessel moving rules, job scheduling and so on. In this paper, the characteristics of pipeless batch plant design are considered to handle the problem by the systems engineering approach. Then, a practical design method known as design-by-analysis is applied to solve such a complex design problem. Based on this concept, a design support system composed of modeling, simulation and evaluation subsystems is developed. This system enables rational decision making through performance evaluation for proposed design of a pipeless batch plant. The usefulness of the system is illustrated by industrial examples. 12 refs., 8 figs., 6 tabs.

British Library Electronic Table of Contents (United Kingdom)

We have colocalized elastin and fibrillin-1 with perlecan in extracellular matrix of tensional and weight-bearing connective tissues. Elastin and fibrillin-1 were identified as prominent components of paraspinal blood vessels, and posterior longitudinal ligament in the human fetal spine and outer annulus fibrosus of the fetal intervertebral disc. We also colocalized perlecan with a synovial elastic basal lamina, where the attached synovial cells were observed to produce perlecan. Elastin, fibrillin-1 and perlecan were co-localized in the intima and media of small blood vessels in the synovium and in human fetal paraspinal blood vessels. Elastic fibers were observed at the insertion point of the anterior cruciate ligament to bone in the ovine stifle joint where they colocalized with perleca...

British Library Electronic Table of Contents (United Kingdom)

Recently, we cloned purpurin cDNA as an upregulated gene in the axotomized fish retina. The retina-specific protein was secreted from photoreceptors to ganglion cell layer during an early stage of optic nerve regeneration in zebrafish retina. The purpurin worked as a trigger molecule for axonal regrowth in adult injured fish retina. During zebrafish development, purpurin mRNA first appeared in ventral retina at 2 days post-fertilization (dpf) and spread out to the outer nuclear layer at 3 dpf. Here, we investigated the role of purpurin for zebrafish retinal development using morpholino gene knockdown technique. Injection of purpurin morpholino into the 1-2 cell stage of embryos significantly inhibited the transcriptional and translational expression of purpurin at 3 dpf. In the purpurin mo...

CERN Document Server

A recurrent idea in the study of complex systems is that optimal information processing is to be found near bifurcation points or phase transitions. However, this heuristic hypothesis has few (if any) concrete realizations where a standard and biologically relevant quantity is optimized at criticality. Here we give a clear example of such a phenomenon: a network of excitable elements has its sensitivity and dynamic range maximized at the critical point of a non-equilibrium phase transition. Our results are compatible with the essential role of gap junctions in olfactory glomeruli and retinal ganglionar cell output. Synchronization and global oscillations also appear in the network dynamics. We propose that the main functional role of electrical coupling is to provide an enhancement of dynamic range, therefore allowing the coding of information spanning several orders of magnitude. The mechanism could provide a microscopic neural basis for psychophysical laws.

British Library Electronic Table of Contents (United Kingdom)

PurposeTo compare the effectiveness and safety of 25- and 23-gauge sutureless microincision vitrectomy surgery (MIVS) in the management of various vitreoretinal diseases.MethodsEighty-five consecutive patients undergoing sutureless vitrectomy during January to April 2008 were randomized to either 25- or 23-gauge MIVS. Data collected prospectively included best-corrected visual acuity (BCVA), operation time, postoperative visual recovery, postoperative anterior segment change, and complications.ResultsThe most common indications for MIVS were macular hole, macular pucker, vitreous haemorrhage, and diabetic traction retinal detachment. Mean operation times of the 25-gauge (n=38) and 23-gauge groups (n=47) were 33.68 and 34.47?min, respectively (P=0.942). Mean BCVA improved significantl...

Science.gov (United States)

... Amount Background Radiation Blood vessel central line, PICC (peripherally inserted central catheter) or port placement, simple 0.4 mSv ...

Energy Technology Data Exchange (ETDEWEB)

More details about the construction of the Terra Nova floating production, storage and offloading (FPSO) vessel are provided. The vessel was built in the Daewoo shipyard in South Korea, and is now undergoing final fitting at Bull Arm, near St. John's, Newfoundland. When complete, the vessel will operate 350 km offshore, southeast of St. John's. It is 291 metres long and 45.5 metres wide and has a capacity of 960,000 barrels of oil. Although the FPSO will hold less than half of the last giant supertanker which sailed for Irving Oil, it has a crew of 81, four times the size of the supertanker, reflecting the technical uniqueness of the vessel and the intense pre-occupation with safety associated with the combination of winds, ice, waves, and shallow water around the Grand Banks. Also described is the alliance system of partnership between the oil companies and the main contractors. The ...

Energy Technology Data Exchange (ETDEWEB)

The use of deuterium-tritium fuel in the Compact Ignition Tokamak will require applying remote handling technology for ex-vessel maintenance and replacement of machine components. Highly activated and contaminated components of the fusion devices auxiliary systems, such as diagnostics and RF heating, must be replaced using remotely operated maintenance equipment in the test cell. In-vessel remote maintenance included replacement of divertor and first wall hardware, faraday shields, and for an in-vessel inspection system. Provision for remote replacement of a vacuum vessel sector, toroidal field coil or poloidal field ring coil was not included in the project baseline. As a result of recent coil failures experienced at a number of facilities, the CIT project decided to reconsider the question of remote recovery from a coil failure and, in January of 1990, initiated a coil replacement study. This study ...

UK PubMed Central (United Kingdom)

The pathogenesis of Pseudomonas aeruginosa disseminated infections depends on bacterial interaction with blood vessels. We have hypothesized that in order to traverse the endothelial barrier, bacteria...Full Text Available

UK PubMed Central (United Kingdom)

Evidence is presented that phorbic acid is formed in the latex producing cell system, rather than in photosynthetic or chlorophyll-free tissues of Euphorbia resinifera Berg. When a...Full Text Available

UK PubMed Central (United Kingdom)

1. Nitric oxide generation is important in the regulation of resistance vessel tone. Until now, however, there has been no evidence of such a role for basal generation of nitric oxide in the skin microcirculation...Full Text Available

International Nuclear Information System (INIS)

English Mar 1998 p. 278 France Omura, M. Aida, N. Sekido, K. Kakehi,

Science.gov (United States)

Mist eliminators for flue gas desulphurisation units remove liquid droplets entrained in the flue gas leaving the SO/sub 2/-absorber vessels. The commercial designs currently available are described.

UK PubMed Central (United Kingdom)

BackgroundVascular stents are small tubular scaffolds used in the treatment of arterial stenosis (narrowing of the vessel). Most vascular stents are metallic and are deployed either...Full Text Available

International Nuclear Information System (INIS)

An overview is presented of the FFTF reactor and plant together with descriptions of core components, core internals, core system, primary and secondary control rod system, reactor instrumentation, reactor vessel and closure head, and supporting test programs.

UK PubMed Central (United Kingdom)

Pseudoaneurysms related to the superior mesenteric artery (SMA) are a recognised complication of trauma to the vessel, and successful treatment with stenting has been previously described. We report...Full Text Available

UK PubMed Central (United Kingdom)

Gradual occlusion (O) of the swine left circumflex coronary artery (LCX) with an ameroid occluder results in complete O within 3 weeks, collateral vessel development, and compensatory hypertrophy....Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The current status of the ZTH vacuum liner design is covered by this report. ZTH will be the first experiment to be installed in the CPRF (Confinement Physics Research Facility) at the Los Alamos National Laboratory and is scheduled to be operational at the rated current of 4 MA in 1992. The vacuum vessel has a 2.4 m major radius and a 40 cm minor radius. Operating parameters which drive the vacuum vessel mechanical design include a 300 C bakeout temperature, an armour support system capable of withstanding 25 kV, a high toroidal resistance, 1250 kPa magnetic loading, a 10 minute cycle time, and high positional accuracy with respect to the conducting shell. The vacuum vessel design features which satisfy the operating parameters are defined. The liner is constructed of Inconel 625 and has a geometry which alternates sections of thin walled bellows with rigid ribs. These composite sections span between pairs of the 16 ...

UK PubMed Central (United Kingdom)

The bulbar conjunctiva is one of the few areas in which blood flow in the peripheral vasculature can be directly and noninvasively observed in the human. Although extensive literature exists describing...Full Text Available

International Nuclear Information System (INIS)

ARIES-AT is a 1000 MWe conceptual fusion power plant design with a very low projected cost of electricity. The design contains many innovative features to improve both the physics and engineering performance of the system. From the safety and environmental perspective, there is greater depth to the overall analysis than in past ARIES studies. For ARIES-AT, the overall spectrum of off-normal events to be examined has been broadened. They include conventional loss of coolant and loss of flow events, an ex-vessel loss of coolant, and in-vessel off-normal events that mobilize in-vessel inventories (e.g., tritium and tokamak dust) and bypass primary confinement such as a loss of vacuum and an in-vessel loss of coolant with bypass. This broader examination of accidents improves the robustness of the design from the safety perspective and gives additional confidence that the facility can meet the no-evacuation ...

International Nuclear Information System (INIS)

We have investigated the hemostatic properties of the free-electron laser (FEL) and compared these properties to the most commonly used commercial lasers in neurosurgery, CO_2 and Nd:YAG, using an acute canine model. Arterial and venous vessels, of varying diameters from 0.1 to 1.0 mm, were divided with all three lasers. Analysis of five wavelengths of the FEL (3.0, 4.5, 6.1, 6.45, and 7.7 microns) resulted in bleeding without evidence of significant coagulation, regardless of whether the vessel was an artery or vein. Hemorrhage from vessels less than 0.4 mm diameter was subsequently easily controlled with Gelfoam registered (topical hemostatic agent) alone, whereas larger vessels required bipolar electrocautery. No significant charring, or contraction of the surrounding parenchyma was noted with any of the wavelengths chosen from FEL source. The CO_2 laser, in continuous mode, easily coagulated ...

International Nuclear Information System (INIS)

The fabrication of the ZT-40 torus, a large complex all-ceramic toroidal plasma containment vessel, is described. Several glass sealants covering the temperature range of 500 to 1300"0C, were developed and used to ''braze'' segments of the torus together, sapphire windows to the torus and the required pump-out and diagnostic parts to the ceramic vacuum vessel. Designs of window seals were developed that allowed sealing of the sapphire windows in a vertical position with minimum sealing glass flow.

International Nuclear Information System (INIS)

Large scale steam storage power generation, one of the new energy storage systems for the future of inflexible electric power sources consisting of nuclear and coal power plants has been studied on the subjects of the systems to be attached to coal and nuclear power units, of the definition of storage efficiency and of the vertical steam storage vessel technology. Steam storage power generation may be hopeful for its higher efficiency similarly defined as of pumped storage plants while high temperature heat storage and the internal structure of large vertical steam storage vessel (accumulator) need to be developed. (author).

International Nuclear Information System (INIS)

The Four years of the IMPACT, 'Integrated Modular Plant Analysis and Computing Technology' project Phase 1 have been completed. The verification study of Severe Accident Analysis Code SAMPSON prototype developed in Phase 1 was conducted in two steps. First, each analysis module was run independently and analysis results were compared and verified against separate-effect test data with good results. Test data are as follows: CORA-13 (FZK) for the Core Heat-up Module; VI-3 of HI/VI Test (ORNL) for the FP Release from Fuel Module; KROTOS-37 (JRC-ISPRA) for the Molten Core Relocation Module; Water Spread Test (UCSB) for the Debris Spreading Model and Benard's Melting Test for Natural Convection Model in the Debris Cooling Module; Hydrogen Burning Test (NUPEC) for the Ex-Vessel Thermal Hydraulics Module; PREMIX, PM10 (FZK) for the Steam Explosion Module; and SWISS-2 (SNL) for the Debris-Concrete Interaction Module. Second, with the Simulation Supervisory System, up to ...

Science.gov (United States)

PPARgamma agonists have been proposed to exert more than metabolic benefits, particularly by anti-inflammatory mechanisms. We hypothesized that pioglitazone might modulate inflammatory and vascular responses to lipopolysaccharide (LPS). In a placebo-controlled parallel-group study in 18 healthy male subjects, the E. coli endotoxin model of inflammation (20 IU/kg i. v.) was employed to test the effect of 60 mg pioglitazone over nine days on inflammatory cytokines. Macrovascular function and microvascular blood flow were assessed by brachial artery ultrasound and retinal blood flow parameters, respectively. Pioglitazone increased brachial artery diameter by 5.6% but had no effect on other outcome parameters under resting conditions. LPS increased cytokine levels to peak concentrations of 91.3+/-22.5 ng/ml (IL-6), 261.4+/-60.0 ng/ml (TNFalpha), and 524.5+/-15.3 ng/ml (VCAM-1). The endotoxin caused microvascular vasodilation and increased retinal ...

British Library Electronic Table of Contents (United Kingdom)

This study describes the chemical composition of the essential oil of Artemisia maritima (Am.Oil) and the pharmacological basis for its medicinal use in gut and airways disorders. Twenty five compounds, composing 93.7% of the oil, were identified; among these, chrysanthenyl propionate and elixene were identified for the first time from any Artemisia species. The Am.Oil (0.3?1.0 mg/mL) suppressed spontaneous and high K+ (80 mM)-induced contractions in isolated rabbit jejunum, suggestive of an antispasmodic effect mediated possibly through calcium channel blockade. The calcium channel blockade activity was confirmed when pre-treatment of the tissue with Am.Oil (0.01?0.03 mg/mL) shifted the Ca++ concentration-response curves to the right, similar to verapamil and papaverine. In isolated trach...

International Nuclear Information System (INIS)

Neutron energy spectra were measured for two OSURR experimental facilities. The method of multiple foil activation was used with the SAND-II neutron spectrum unfolding code to obtain spectral data for the Central Irradiation Facility and Rabbit tube. Limited data was obtained for the thermal column using only gold foils. Calculations were made of the neutron environment in various locations using the MORSE code. A shift towards higher neutron energies was observed comparing results for LEU and HEU cores. A slight loss in total thermal neutron flux was measured for all positions. Calculational results show reasonable agreement with measured data.

Energy Technology Data Exchange (ETDEWEB)

Two lines of mouse tumor cells were shown to be capable of aggregating mouse and rabbit platelets in vitro. This process required higher Mg/sup 2 +/ concentrations than were needed by other commonly used platelet-aggregating agents. Platelet-aggregating activity was also found in tumor cell membrane fragments. This membrane-bound platelet-aggregating material contained protein, lipid, and carbohydrate moieties. The presence of all three appeared to be essential for stimulating platelet aggregation. Destruction of any component abolished its activity. Platelet aggregation induced by tumor cell membrane fragments was associated with a secretory release reaction. In this process, growth-promoting activity for tumor cells was also released from platelets. These results underline the importance of platelets in establishing tumor metastases.

International Nuclear Information System (INIS)

Techniques of chemical analysis, amino acid sequencing and autoradiography are being used to study the frequency of incorporation of normally noncoded amino acids into hemoglobins and seminal fluid proteins. We are studying, by the sequencing of radiolabeled proteins followed by the recovery of ["3H] isoleucine phenylthiohydantoin by high-performance liquid chromatography, the frequency at which normally noncoded isoleucine is incorporated into hemoglobin because of base-substitution mutations versus translational errors. Irradiation increases the isoleucine content of human hemoglobin and the frequency of substitution of isoleucine for specific amino acids in rabbit hemoglobin. Studies to date indicate that these techniques have been developed sufficiently for initial analysis of the potential of drugs and environmental pollutants to induce base-substitution mutations in mammalian somatic cells.

International Nuclear Information System (INIS)

Purpose: Three-dimensional rotational angiography (3DRA) is a new technique based on a rotational angiographic acquisition able to display arterial vessels in a 3D rendering mode. The system was mainly developed for neuroradiological evaluations but preliminary extracranial experiences have also been reported. The aim of our work was to compare the results of three-dimensional angiography of the carotid arteries done with high-flow injection of contrast medium from the aortic arch with the results of selective angiography. Materials and methods: Twenty patients underwent digital angiography of the supra-aortic vessels in order to quantify a stenosis of the carotid bifurcations previously detected at Doppler Ultrasound. Examinations were performed with the Philips Integris Allura system provided with the rotational angiography (RA) tool connected to a workstation for three-dimensional reconstruction able to display vessels ...

Science.gov (United States)

Laparoscopic orchiopexy has gained popularity in recent years. However, the decision when to perform one-stage laparoscopic orchiopexy without division of the spermatic vessels versus initial ligation of the spermatic vessels followed later by orchiopexy is not clear. A new laparoscopic classification to facilitate decision-making during laparoscopy, according to the position of the impalpable testis and the relation of the spermatic vessels and vas deferens to the internal ring, with a management protocol based on this classification is presented. Over a 2-year period, a total of 37 boys with 52 impalpable gonads underwent a laparoscopic procedure. Four laparoscopic types of testis were noted: type I: no testis visualized; type II: a testis seen at the internal ring with the vas and vessels looping to the internal ring; type III: testis at the internal ring, with vas and vessels ...

Energy Technology Data Exchange (ETDEWEB)

AREVA is the world leader in the design and construction of nuclear power plants, the manufacture of heavy components, and the supply of nuclear fuel and nuclear services such as maintenance and inspection. The Equipment Division provides the widest range of nuclear components and equipment, manufactured at its two facilities in Jeumont, northern France, and St. Marcel, in Burgundy. The St. Marcel plant, set on 35 ha (87.5 acres) near Chalon-sur-Saone, was established in 1973 in a region with a long history of specialized metalworking and mechanical activities to meet the demand for non-military nuclear requirements in France. The site offers two advantages: - excellent facilities for loading and transporting heavy components on the Saone river, - it's proximity to other group sites. Since its completion in 1975, the Chalon/St. Marcel facility has manufactured all the heavy components for French pressurized water reactors (PWRs) ranging from 900 MW to 1500 MW. It has also ...

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A portion of the active site of rabbit skeletal myosin near the ribose ring of ATP can be labeled by the photoaffinity analogue 3{prime}(2{prime})-O-(4-benzoylbenzoyl)adenosine triphosphate (Bz{sub 2}ATP). The specificity of the photolabeling was assured by first trapping ({sup 14}C)Bz{sub 2}ATP at the active site by use of thiol cross-linking agents. Five radioactive peptides were isolated by high-performance liquid chromatography after extensive trypsin and subtilisin digestion of photolabeled myosin subfragment 1. Four of these peptides were sequenced by Edman techniques, and all originated from a region with the sequence Gly-Glu-Ile-Thr-Val-Pro-Ser-Ile-Asp-Asp-Gln, which corresponds to rabbit myosin heavy chain residues 312-328. The fifth labeled peptide had an amino acid composition appropriate for residues 312-328. Amino acid composition, radiochemical analysis, and sequence data indicate that Ser-324 is the major amino acid residue ...

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(Materials and Methods) (I) VX/sub 2/ carcinoma was transplanted to the rabbit tibia, sup(99m)Tc-MDP was intravenously injected when bone destruction was radiologically seen. Preoperative scintigraphs, postoperative one of the resected tibia and fibra and scintigraphs of sliced tumor were compared with each other. Tissue fragments were collected from the sliced tumor, and RI was measured to compare concentration rates at different parts together with histological investigations. (II) Tetracycline was given to the rabbit of Experiment (I) to compare with the concentration of sup(99m)Tc-MDP. (III) Microautoradiography method was done on the experimental animals for investigation of the concentration of sup(99m)Tc-MDP. (Results) (I) Localization of sup(99m)Tc-MDP was increased at the sites of tumorous bone formation, of reactive bone formation at tumor edges, and of cartilage calcification, with little concentration at tumor cells or necrotic ...

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Previous in vitro studies have demonstrated that Ho:YLF laser is capable of inducing physical and chemical changes on dental surfaces treated for caries prevention. The temperature in the pulp chamber was in vitro evaluated to as a function of the power and frequency of the laser irradiation. The purpose of this work is to verify the occurrence of pulp inflammation after Ho:YLF laser irradiation using different parameters in rabbits' teeth. The premolars and molars of ten rabbits (NZB) were divided in two groups according to the irradiation energy values of a Ho:YLF laser prototype operating at 2.065{mu}m wave length, frequency of O,5Hz and pulse length of 250{mu}s. An group A teeth were irradiated with using ten pulses of 334mJ/pulse of a Ho:YLF laser prototype operating at O.5Hz, and group B, with 512mJ/pulse. Animals were killed by transcardiac perfusion and the samples were prepared for histopathological analysis. The in vitro ...

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The affinity label 8-((4-bromo-2,3-dioxobutyl)thio)adenosine 5{prime}-triphosphate (8-BDB-TA-5{prime}-TP) reacts covalently with rabbit muscle pyruvate kinase, incorporating 2 mol of reagent/mol of enzyme subunit upon complete inactivation. Protection against inactivation is provided by phosphoenolpyruvate, K{sup +}, and Mn{sup 2+} and only 1 mol of reagent/mol of subunit is incorporated. The authors have now identified the resultant modified residues. After reaction with 8-BDB-TA-5{prime}-TP at pH 7.0, modified enzyme was incubated with ({sup 3}H)NaBH{sub 4} to reduce the carbonyl groups of enzyme-bound 8-BDB-TA-5{prime}-TP and to introduce a radioactive tracer into the modified residues. Following carboxymethylation and digestion with trypsin, the radioactive peptides were separated on a phenylboronate agarose column followed by reverse-phase high-performance liquid chromatography in 0.1% trifluoroacetic acid with an acetonitrile gradient. Gas-phase sequencing ...

International Nuclear Information System (INIS)

In General Electric's design of the Simplified Boiling Water Reactor (SBWR), The depressurization valves (DPV) are installed in the reactor pressure boundary: four are connected to the reactor vessel by means of nozzles, and two more are located on the main steam pipes (one DPV for each line), which act during particular transients and/or loss of coolant accidents (LOCA), consequently providing the reactor vessel with a safe quick depressurization system. Once the vessel is de pressurised, the passive gravity-driven cooling system (GDCS) starts to operate, permitting the injection of water required for continuous core cooling. DPVs are leak tight, with welded flaps, actuated by a [striker[hammer***] which is activated by an explosive mixture. The dynamic loads that open these valves include, in addition to those produced by steam (typical in any thermodynamic transient with open/close valves), other important loads that are ...

International Nuclear Information System (INIS)

Certain postulated faults during refuelling of AGRs may give rise to compacted fuel and graphite sleeve debris. This debris must be maintained below some safe limiting temperature. As part of a programme to assess the benefits of natural convection in cooling such debris in a region experiencing no forced cooling, a simple geometry incorporating typical debris has been studied both experimentally and by prediction. The experiment comprised an array of electrically heated fuel rods mounted co-axially in a closed cylindrical vessel and surrounded by fragments of graphite. The vessel was cooled on its cylindrical surface, the ends being insulated. Rods and vessel wall were thermocoupled. Tests covered a range of temperature and pressures in both CO_2 and N_2. Significant natural convection heat removal was demonstrated, particularly at high pressure. Predictions utilising the PHOENICS code agreed well with measured ...

International Nuclear Information System (INIS)

We report a patient who developed occlusion of the intracranial major arteries induced by radiation therapy for craniopharyngioma. The patient, a 9-year-old boy, presented with deterioration of vision, nausea and vomiting. He underwent a right ventriculo-peritoneal shunt operation, and the tumor was partially removed. Postoperatively, he received focal radiation therapy with total of 60 Gy. Preoperative cerebral angiography, cerebral vessels had no sigh of occlusive lesion or stenosis. One year after irradiation, he started to have repeated cerebral ischemic attacks. But no regrowth of the tumor was detected on CT scans. Two years and 8 months after irradiation, he suddenly had right hemiparesis. Cerebral angiography revealed severe stenosis of the right anterior cerebral artery (precommunicating segment), middle cerebral artery (horizontal portion) and terminal portion of the right carotid artery. Left carotid angiography showed complete occlusion of the terminal ...

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Visual excitation is initiated by the absorption of a photon by the 11-cis retinal chromophore bound within the pigment called rhodopsin. We have used a variety of vibrational spectroscopies to obtain information about the vibrational nuclear dynamics that lead to this efficient photochemical isomerization. The cis-trans isomerization in rhodopsin is complete in only 200 fs. The extreme speed of this process, which is consistent with the {approximately}50 fs lifetime indicated by the spontaneous emission yield, suggests that the photochemistry involves non-stationary states or vibrational coherence. Recent studies have in fact observed vibrationally coherent oscillations of the ground state photoproduct called bathorhodopsin following impulsive excitation of the rhodopsin reactant. This conclusively demonstrates that the isomerization process in rhodopsin is vibrationally coherent. These observations further suggest that the isomerization quantum yield is directly ...

British Library Electronic Table of Contents (United Kingdom)

Introduction: We have evaluated the ability of a semi-automated, optomotor reflex method to assess drug-induced visual dysfunction, in albino and pigmented rats and mice. Methods: Male Han Wistar (HW) and Long Evans (LE) rats and mice (CD-1 and C57BL/6) were tested in a chamber formed by 4 computer monitors displaying a rotating vertical grating, to elicit head-tracking movements. The highest visible grating frequency was taken as the threshold of visual acuity, in cycles per degree (c/d). Animals received an intravenous infusion of either sodium iodate (50mg/kg) or 0.9% w/v NaCl (aq). They were tested 2h later, then re-tested daily for a further 3days. The time course of the effect was assessed in HW rats over a 6-week period, including electron microscopy, and immunohistochemical analysi...

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Previous reports have stressed the importance of the nutrient blood supply in rib grafts transferred by microvascular anastomoses. In the present experimental study, we have demonstrated that a rib graft transferred by microvascular anastomoses based on periosteal vessels can survive; vascular clearing studies demonstrated that the vascularity of these grafts extends not only into the cortex but the medulla as well. The relative facility of harvesting these grafts (compared with those based on nutrient vessels) should make them the favored choice. Technetium bone scintigraphy proved accurate in the assessment of both vascular pattern and microanastomotic patency. Tetracycline labeling did not correlate well with the patency of a rib graft's pedicle blood supply.

International Nuclear Information System (INIS)

Weld metal, base material and stainless steel overlay specimens for Charpy tests and static tensile tests were irradiated for a year in a power reactor of the Bohunice nuclear power plant in place of the evaluated surveillance specimens. The material of the specimens was identical with that of the WWER-440 reactor pressure vessels, and was exposed to a fluence of (1.2 - 4.5) x 10"2"3 m"-"2 (E > 0.5 MeV) at approximately 270 degC. Some of the irradiated as well as unirradiated specimens were subjected to regeneration annealing at 475 degC for 168 h. The behavior of the materials after irradiation and annealing was evaluated. (author). 33 tabs., 32 figs., 8 refs.

International Nuclear Information System (INIS)

Object: To suppress a quantity of impurities in a coolant fed into a reactor vessel. Structure: The concentration of oxygen in a coolant flowing from a condensation desalting instrument into a feed and condensation piping is measured by an oxygen-concentration detector to feed its signal to an adjusting instrument. A degree of opening of an oxygen flow control valve to maintain the concentration of oxygen in the cooling water flowing within the pipe in the range from about 10 to about 200 ppb. Also, the concentration of oxygen in the cooling water fed to the desalting instrument is maintained at a level less than 2 ppb. Thereby, the total amount of iron flown into the vessel can be suppressed to a fine amount such as less than about 1 ppb. (Kawakami, Y.).

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The use of Floating Production Storage and Offloading (FPSO) vessels to develop UK offshore oil fields looks certain to increase. Of the 64 new offshore fields due for development in the next few years, 15 are expected to use FPSO vessels for their production. Most of these are small, short-life fields in the central North Sea which would not justify investment in a fixed platform. Three, however, are large fields west of Shetland, and one, the Foinaven field, is scheduled to be the first commercial development in this area, perhaps setting a precedent. Floating production systems with substantial storage capacity can be the best option in deepwater locations which are remote from existing infrastructure, where the cost of an export pipeline would be prohibitive. (author)

International Nuclear Information System (INIS)

Purpose: To obtain stabilized operation by preventing over heat in emergency cooling pumps upon accidents of flow regulators. Constitution: A pressure suppression chamber pool and a pressure vessel are communicated to each other with a pipeway and the water in the suppression pool is charged by a charging pump to the pipeway. The pipeway is interposed with an emergency cooling pump so as to feed water in the pipeway to the pressure vessel and a water source and the emergency cooling pumps are connected by way of a closed pipeway. Further, the closed pipeway and the pipeway interposed with the charging pump are communicated to each other by way of a connecting pipeway, to which are interposed an instrument for detecting the increase in the temperature of the emergency cooling pumps due to abnormality in the closed pipe (such as troubles in flow regulators) and outputting control signals and an electrically actuated valve controlled by a control ...

International Nuclear Information System (INIS)

The coupled neutron-gamma cross section libraries BUGLE-80 and SAILOR are compared, with focus on gamma production and transport and its sensitivity to the thermal component of the neutron flux. In addition, the importance of the prompt versus delayed components of the gamma source is addressed. Although BUGLE-80 shows some discrepancies in the core region, the two libraries demonstrate similar capability in the vicinity of the pressure vessel and beyond. The delayed fission product gammas from the core have little impact on the local gamma fluxes beyond the pressure vessel. Although thermal neutron capture is the dominant component of the gamma source, there is little sensitivity of the gamma source to uncertainties in the thermal neutron cross sections, due to compensating effects which tend to keep the thermal neutron capture rate relatively constant.

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Automatic ultrasonic testing is presented as a method for recurrent inspections of pressure gas vessels, from validation to practical testing to customised test applications. National and international regulations and standards are presented along with related implementation problems. [German] Es wird die automatisierte Ultraschallpruefung im Bereich der wiederkehrenden Pruefung von Druckgasbehaeltern, als Alternative zur herkoemmlichen, klassischen Wasserdruckpruefung, vorgestellt. Von der Validierung ueber die praktische Erprobung bis hin zur kundenspezifisch entwickelten Pruefapplikation. Es werden die Anforderungen aus nationalen und internationalen Vorschriften und Normen sowie die damit zusammenhaengenden Umsetzungsprobleme behandelt.

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It is necessary to identify those measurable soil parameters which dictate the severity of the corrosion problem for coated irons and steels. When this is done, meaningful accelerated aging tests can be designed to validate the reduced corrosion rate for the planned coating. The following discussion introduces the important concepts and measurement parameters in the (a) design of accelerated aging tests, and (b) evaluation of the planned installation site for corrosion potential. Certain combinations of soil oxidation reduction potential (ORP) or electric potential (Eh), acidity (pH), fertilizer, water table, and soil hydraulic conductivity can result in severe corrosion of buried steel/iron vessels. If there are power lines nearby, additional loss of vessel material to the soil will occur. These factors are discussed.

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This case report evaluates X-ray findings in patients with miliary accumulation of mercury observed after parenteral application of metallic mercury in a suizide attempt. There are certain discrepancies between clinical symptoms and the X-ray findings. A clear demonstration of mercury in coronary blood vessels is possible by fluoroscopy.

Energy Technology Data Exchange (ETDEWEB)

In the hypothetical event of a severe accident in a Light Water Reactor, scenarios in which the reactor pressure vessel (RPV) fails and the core melt mixture (called corium) relocates into the reactor cavity, cannot be excluded. The viscosity (in fact, corium rheological behaviour) plays a major role in many phenomena such as core melt down, discharge from reactor pressure vessel, interaction with structural materials (concrete,...) and spreading in a core-catcher. For these reasons, it is important to be able to predict the rheological behaviour of corium melts of different compositions (essentially based on UO{sub 2}, ZrO{sub 2}, Fe{sub x}O{sub y} and Fe for in-vessel scenarios, plus SiO{sub 2} and CaO for ex-vessel scenarios) at temperatures above solidus temperature. In the case of corium-concrete mixtures, the increase of viscosity depends not only on the increase of particles in the melts but also ...

British Library Electronic Table of Contents (United Kingdom)

Modec International Inc has selected Siemens Water Technologies to provide sea-water reverse osmosis (SWRO) systems for several floating, production, storage and offloading (FPSO) vessels that are to be operated in deep-water locations. Siemens is also supplying a wastewater reuse system to one of Brazils largest refineries.

Science.gov (United States)

... mini-stroke," also called a TIA or a transient ischemic attack . If you have any of these warning signs, ... ur-uhl) (ar-TEE-ree-uhl) (dih-ZEEZ) transient ischemic attack (TRANZ-see-uhnt) (iss-KEE-mik) (uh-TAK) [ ...

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This report forms part of a joint study on a PEFC propulsion system for surface ships, summarized in a presentation to this Seminar, entitled {open_quotes}Study on a Polymer Electrolyte Fuel Cell (PEFC) Propulsion System for Surface Ships{close_quotes}, and which envisages application to a 1,500 DWT cargo vessel. The aspect treated here concerns an experiment in reducing by methanation to a level below 10 ppm the CO that is contained to around 1% in reformate gas.

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The Northeast Gateway Energy Bridge Deepwater Port project was commissioned in 2005 and is based on a proprietary energy bridge shipboard regasification technology. The offshore liquefied natural gas (LNG) facility will be located in federal waters 13 miles southeast of Gloucester and was designed to cope with the extreme weather of the Massachusetts Bay. A dual-buoy system will be capable of ensuring continuous delivery of natural gas. Throughput capacity will range from 400 to over 800 MMcf/d. Vessels used at the port have capacities of 138,000 m{sup 3} and 150,900 m{sup 3} with peak sendout rates of 600 MMcf/d. The vessels have the capacity to rapidly increase and decrease their delivery rates. During periods of peak demand, 2 vessels can be simultaneously accommodated at the port, which has been designed to accommodate larger vessels to maximize future throughput. This presentation presented details ...

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The report presents selected highlights of how research has contributed to the regulatory effort. It explains the research role of the NRC and nuclear safety research contributions in the areas of: pressure vessel integrity, piping, small- and large-break loss-of-coolant accidents, hydrogen and containment, source term analysis, seismic hazards and high-level waste management. The report also provides a summary of current and future research directions in support of regulation.

Science.gov (United States)

PACAP (pituitary adenylate cyclase activating polypeptide) is widely distributed neuropeptide acting via three subtypes of receptors, PAC(1), VPAC(1) and VPAC(2). Here we examined the localisation and nature of PACAP-immunoreactive nerves in the rat thyroid and parathyroid glands and defined the distribution of PAC(1), VPAC(1) and VPAC(2) receptor mRNA's. In the parathyroid gland a large number of nerve fibres displaying PACAP-immunoreactivity were distributed beneath the capsule, around blood vessels and close to glandular cells. Most of the PACAP-nerves were sensory, since they co-stored CGRP (calcitonin-gene-related peptide) and were sensitive to capsaicin-treatment. mRNA's for PAC(1) and VPAC(2) receptors occurred in the parathyroid gland, mainly located in the glandular cells. In the thyroid gland PACAP-immunoreactive nerve fibres were associated with blood vessels, thyroid follicles and parafollicular C-cells. A high degree of ...

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The calculations with the broad-group cross-section library Bugle-96, and atom displacement (dpa) cross sections for iron, both derived from ENDF/B-VI data, result in higher calculated fast neutron fluxes, better agreement of calculations with radiometric dosimeter measurements, and significantly slower dpa rate attenuation through pressure vessel walls relative to the results with their predecessors: the Sailor library and ASTM iron dpa cross sections.

Science.gov (United States)

Solids are separated from a liquid in a gravity settler provided with inclined solid intercepting surfaces to intercept the solid settling path to coalesce the solids and increase the settling rate. The intercepting surfaces are inverted V-shaped plates, each formed from first and second downwardly inclined upwardly curved intersecting conical sections having their apices at the vessel wall.

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This document describes measurements of the directional spectral emittance of four ceramic mold materials. The work was performed with the samples at {approximately} 900{degree}C in a vacuum vessel pumped to {approximately}3 {times} 10{sup {minus}6}Torr. Results conform to expectations derived from prior work done with similar samples.

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Supplement B to the Terra Nova Development Application provides a description of the floating production storage and offloading (FPSO) vessel system selected for the development, a summary of the reasons for selecting the system, and the impact of this selection on the Development Plan, the Benefits Plan, the Environmental Impact Statement and the Socio-Economic Impact Statement. There is also a description of the contractor alliance approach to be used in the Terra Nova Development. Refs., tabs., figs.

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Large scale experiments were performed to determine the effectiveness of thermal glow plug igniters to burn hydrogen in a condensing steam environment due to the presence of water sprays. The experiments were designed to determine if a detonation or accelerated flame could occur in a hydrogen-air-steam mixture which was initially nonflammable due to steam dilution but was rendered flammable by rapid steam condensation due to water sprays. Eleven Hydrogen Igniter Tests were conducted in the test vessel. The vessel was instrumented with pressure transducers, thermocouple rakes, gas grab sample bottles, hydrogen microsensors, and cameras. The vessel contained two prototypic engineered systems: (1) a deliberate hydrogen ignition system and (2) a water spray system. Experiments were conducted under conditions scaled to be nearly prototypic of those expected in Advanced Light Water Reactors (such as the Combustion Engineering ...

International Nuclear Information System (INIS)

In co-operation with the Scientific Planning Department of the Central Research Institute for Vessel- and Turbine Building the construction office of the turbine factory Charkow finished the draft of a slowly running (n = 1500 min"-"1) 2 GW-turboset for the operation of nuclear power plants. The chief purpose of the project was to determine the technical problems that are used to occur during the development of such steam turbines, as well as to settle the most favourable design. (orig./GL).

International Nuclear Information System (INIS)

Active oxygens produced by low-dose irradiation can induce the synthesis of proteins involved in the active oxygen reduction path and can activate the chemical self-defense mechanisms in vivo, which can alleviate the injuries caused by active oxygens themselves. The following findings suggests that it is not only by low-dose irradiation that can induce the responses described above but also by any physical and/or chemical stresses which can produce small amount of active oxygens in vivo. 1. X-irradiation with 0.5 Gy and/or water immersion and restraint induced heat shock protein (HSP)70 in rat stomach cells. HSP70 was also induced in adrenal cells by paraquat administration. 2. The SOD activity in pancreas of rat significantly increased by #gamma#-irradiation with 0.5 Gy. 0.5 Gy irradiation preceeding the alloxan administration significantly suppressed the increase in pancreatic lipid peroxides and in blood glucose levels, degranulation in #beta# cells, and decrease in blood insulin ...

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The Ohio State University Research Reactor (OSURR) is licensed to operate at a maximum power level of 500 kW. A pool-type reactor using flat-plate, low enriched fuel elements, the OSURR provides several experimental facilities including two 6-inch i.d. beam ports, a graphite thermal column, several graphite-isotope-irradiation elements, a pneumatic transfer system (Rabbit), various dry tubes, and a Central Irradiation Facility (CIF). The core arrangement and accessibility facilitates research programs involving material activation or core parameter studies. The OSURR control room is large enough to accommodate laboratory groups which can use control instrumentation for monitoring of experiments. The control instrumentation is relatively simple, without a large amount of duplication. This facilitates opportunities for hands-on experience in reactor operation by nuclear engineering students making reactor parameter measurements. For neutron activation analysis and ...

Science.gov (United States)

A tick/rickettsial survey in various parts of Switzerland revealed the presence of a new, hitherto undescribed spotted fever group rickettsia ("Swiss agent") in up to 11.7% of I. ricinus collected off vegetation. Infection in ticks was found to be generalized with rickettsiae developing intracellularly and occasionally also intranuclearly. As a result of massive growth in ovarial tissues, including the germinative cells, the rate of transovarial and filial infection was 100%. The "Swiss agent" appears to be nonpathogenic for guinea pigs, domestic rabbits, and Swiss mice, but in male meadow voles (Microtus pennsylvanicus) it produces a microscopically detectable infection in the tunica vaginalis. The rickettsia grows well in tissue culture systems including chick embryo fibroblast, Vero, and vole tissue cells, when inoculated via yolk sac into 5-day-old hens' eggs, it kills 100% of the embryos after 5 to 7 days. Antigenic relatedness of the "Swiss agent" to ...

International Nuclear Information System (INIS)

Treatment of cultures of 3T3-L1 cells with methylisobutyl-xanthine and dexamethasone has been shown to result in accumulation of lipid and conversion to the morphology of adipocytes in more than 90% of the cells. The status of the stimulatory (Gs), inhibitory (Gi) and Go-proteins during the course of 3T3-L1 differentiation was examined. The amount of alpha subunit of Gs (#alpha#Gs), assayed by radiolabeling in the presence of cholera toxin and ["3"2P]NAD"+, increased upon differentiation as previously described by others. The amounts of #alpha#Gi and #alpha#Go assayed by radiolabeling in the presence of pertussis toxin and ["3"2P]NAD"+ increased 3-fold upon differentiation. Immunoblots of cell membranes subjected to gel electrophoresis in sodium dodecyl sulfate were probed with two rabbit antisera raised against bovine brain #alpha#Go and with one raised against the#beta#-subunit of the bovine rod-outer-segment G-protein, referred to as transducin. The ...

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Two overlapping cDNA clones encoding human DNA topoisomerase II were identified by two independent methods. In one, a human cDNA library in phage {lambda} was screened by hybridization with a mixed oligonucleotide probe encoding a stretch of seven amino acids found in yeast and Drosophila DNA topoisomerase II; in the other, a different human cDNA library in a {lambda}gt11 expression vector was screened for the expression of antigenic determinants that are recognized by rabbit antibodies specific to human DNA topoisomerase II. The entire coding sequences of the human DNA topoisomerase II gene were determined from these and several additional clones, identified through the use of the cloned human TOP2 gene sequences as probes. Hybridization between the cloned sequences and mRNA and genomic DNA indicates that the human enzyme is encoded by a single-copy gene. The location of the gene was mapped to chromosome 17q21-22 by in situ hybridization of a cloned fragment to ...

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The overall objective of this project has been to develop immunochemical methods to quantitate unique DNA base damages in order to facilitate studies on radiation-induced damage production and repair. Specifically, we have been using antibodies raised to damaged bases to quantitate unique lesions in model systems in order to evaluate their potential biological consequences. Our approach has been to synthesize modified nucleotides or nucleosides, conjugate them to protein carriers, and use the conjugates as immunogens in rabbits or to prepare monoclonal antibodies. We have been studying damages that are stable radiolysis products found in X-irradiated DNA and thus of potential biological consequence. Our aim is to build an in vitro and in vivo data base on the interactions between model DNA lesions and such cellular enzymes as DNA polymerases and repair endonucleases. Initial studies have focused on pyrimidine ring saturation products (thymine glycol.and ...

Science.gov (United States)

The waterjet technique enables precise tissue dissection without thermal damage and with preservation of vessels in general surgery. In neurosurgery, these qualities could help to avoid damage of intact brain parenchyma in tumour resections. The present study reports our first results with this technique in brain metastases. Ten patients with intracranial metastases underwent surgery with the aid of the waterjet. Resection was performed in combination with conventional neurosurgical methods. The follow-up consisted of neurological examination and MRI studies. Intraoperatively, the device was easy to handle. No complications due to the device were observed. Vessels were preserved at pressures below 20 bars. Six of the tumours consisted of soft tissue which was poorly demarcated from the surrounding brain. In these tumours, the waterjet was very helpful. It enabled tumour debulking by aspiration and - more important - precise separation of tumour ...

International Nuclear Information System (INIS)

Yield stress elevations (#DELTA##sigma#_y) in pressure vessel steels irradiated at intermediate flux and fluence systematically decreased with increasing temperature and decreasing copper and nickel content. Lower stress relief temperature also decreased #DELTA##sigma#_y at bulk copper concentrations greater than about 0.3%. The dependence of #DELTA##sigma#_y on irradiation temperature between 260 and 316 C increased with copper and nickel content and decreased with phosphorus content. When normalized by the average #DELTA##sigma#_y, the fractional temperature dependence correlates with a simple empirical chemistry factor of copper and phosphorus. The correlation predicts data on the irradiation temperature dependence of #DELTA##sigma#_y found in the literature within a standard error of about 0.3 MPa/degree C and is consistent with current understanding of hardening mechanisms. However, questions remain about the effects at very low flux and finer scale variations ...

International Nuclear Information System (INIS)

In interventional radiology (IVR) of cerebral aneurysms, it is important to understand the form and physical relationships between the cerebral aneurysm and the surrounding vessels. However, because the vessels in the head area are highly complex, it can be difficult to comprehend the structure using conventional angiography. Therefore, three-dimensional rotational angiography (3D-RA) has been used in recent years. This article discusses studies of the spatial resolution of 3D-RA. We reconstructed 3D-RA of an acrylic slit phantom (slit widths: 0.5, 0.75, 1.0, 1.5 mm) and examined spatial resolution by visual evaluation and profile curves. When the slit phantom was arranged to avoid the effect of beam hardening, the spatial resolution of 3D-RA was found to be as high as 0.75 mm. When the slit phantom was placed orthogonal to the rotational axis of the C-arm, the spatial resolution of 3D-RA was decreased because of the cone angle effect of ...

International Nuclear Information System (INIS)

Spent oxide fuels are reduced in a molten salt of CaCl_2-CaF_2 to convert them into metals, then melted in an Fe-U bath disposed in an electrolytic refining vessel and brought into contact with molten Mg, to extract transuranium elements and rare earth elements contained in the Fe-U bath as metals in the molten Mg. Then molten Mg is removed and the residue is brought into contact with KCl-LiCl molten salt and electrolyzed using the Fe-U as an anode. Then, uranium is recovered by deposition on an iron cathode disposed in chloride electrolytes of the electrolytic refining vessel. Uranium and transuranium elements can be thus separated and, for example, depleted uranium for use in blanket fuels can be recovered easily. This can greatly reduce the temporary storage amount of depleted uranium, to eliminate requirement for a large-scaled facility used exclusively for storing uranium and long time management for uranium. (T.M.).

Science.gov (United States)

The long operating cycle simplified boiling water reactor is a reactor concept that pursues both safety and the economy by employing a natural circulation reactor core without a refueling, a passive decay heat removal, and an integrated building for the reactor and turbine. Throughout the entire spectrum of the design basis accident, the reactor core is kept covered by the passive emergency core cooling system. The decay heat is removed by the conventional active low-pressure residual heat removal system. As for a postulated severe accident, the suppression pool water floods the lower part of the reactor pressure vessel (RPV) in the case when core damage occurs, and the in-vessel retention that keeps the melt inside the RPV is achieved by supplying the coolant. The containment adopts a parallel-double-steel-plate structure similar to a hull structure, which contains coolant between the inner and outer walls to absorb the heat transferred from ...

Energy Technology Data Exchange (ETDEWEB)

Five corrosion probes were received from West Valley Nuclear Services for evaluation in simulated tank 8D-2 3rd-stage sludge wash slurry. The same waste slurry simulated was also used in a series of ongoing corrosion studies assessing the effects of in-tank sludge washing on the integrity of tank 8D-2. Two of the corrosion probes were installed in the coupon corrosion test vessels operating at {approximately}150{degrees}F to compare performance of the probes with that observed by coupon tests conducted in the same vessels. Corrosion rate data calculated from electrical resistance measurements of the corrosion probes were evaluated for this study using two slightly different approaches. One approach uses the total length of exposure of the probe to give a ``time-averaged`` value of the corrosion rate. The other approach uses a shorter period of time (relative to the length of the test) in the calculation of corrosion rate, and is referred to as ...

Energy Technology Data Exchange (ETDEWEB)

Safety and environmental assessments have been made of conceptual fusion power plant designs employing silicon carbide composites (SiC/SiC) as the first wall and blanket structure material. These have used similar analysis methods to earlier studies of designs based on vanadium alloy or low-activation martensitic steel, allowing direct comparisons. The very low short-term activation of silicon carbide results in an almost insignificant level of decay heat in postulated loss of coolant accidents, and a lower {gamma}-dose rate on the timescale of relevance to handling for maintenance operations. However on the longer time-scale, of interest in possible recycling operations, decommissioning and waste management, SiC/SiC appears to perform no better than vanadium alloy or low-activation martensitic steel, due in part to the activation of impurities in a realistic composition. Furthermore, its increased neutron transparency may result in higher activation in the vacuum ...

International Nuclear Information System (INIS)

The multidimensional countercurrent two-phase flow regimes that occur in a pressurized-water reactor (PWR) vessel downcomer during the refill phase of a large-break loss-of-coolant accident are studied using a transparent 1/10 scale model of a PWR vessel. The various flow regimes and their distribution in the downcomer have been identified and mapped for a range of air-water flooding experiments. The two-phase flow patterns that are identified in the downcomer included various types of film flows, droplet flows, countercurrent churn flows and cocurrent flows depending on the flooding condition. Through observation of the two-phase flow dynamics it was deduced that the physical mechanisms associated with the flooding processes could be separated into a liquid entrainment process and a film flow reversal process. In addition to the above exercise, the effect of non-uniform injection of water into the downcomer via different combinations of cold ...

Energy Technology Data Exchange (ETDEWEB)

A lightweight, low permeability liner for graphite epoxy composite compressed gas storage vessels. The liner is composed of polymers that may or may not be coated with a thin layer of a low permeability material, such as silver, gold, or aluminum, deposited on a thin polymeric layer or substrate which is formed into a closed bladder using torispherical or near torispherical end caps, with or without bosses therein, about which a high strength to weight material, such as graphite epoxy composite shell, is formed to withstand the storage pressure forces. The polymeric substrate may be laminated on one or both sides with additional layers of polymeric film. The liner may be formed to a desired configuration using a dissolvable mandrel or by inflation techniques and the edges of the film seamed by heat sealing. The liner may be utilized in most any type of gas storage system, and is particularly applicable for hydrogen, gas mixtures, and oxygen used for vehicles, fuel ...

Energy Technology Data Exchange (ETDEWEB)

Work on this coke oven gas cleaning demonstration project (CCT-II) this quarter has been focused on Phase IIB tasks, and include engineering, procurement, construction, and training. Additionally, plans for changes in the operating schedule of the coke plant that affect the demonstration project are described. Engineering efforts are nearly complete. Remaining to be finalized is an assessment of electrical heat tracing/insulation needs for pipe lines, assessment of fire protection requirements, and instrument modifications. Procurement of all major equipment items is complete, except for possible additions to fire fighting capabilities. Major focus is on expediting pipe and structural steel to the project site. Civil construction is complete except for minor pads and bases as required for pipe supports, etc. Erection of the hydrogen sulfide and ammonia scrubber vessels is complete. Installation of scrubber vessel internals is underway. A ...

International Nuclear Information System (INIS)

As for No.2 plant in Sendai Nuclear Power Station, which is the fourth nuclear power generation facilities in Kyushu Electric Power Co., Inc., all works have been completed, and at present, the final trial operation is under way. In No.2 plant, many new techniques for raising the reliability and safety, improving the maintainability and reducing radiation exposure were introduced on the basis of the operation experience of PWRs obtained so far, similarly to No.1 plant. In this paper, the main items of the new techniques related to the design and construction of the plant are reported. No. 2 plant is a first improved and standardized plant having the thermal output of 2660 MW for standard three-loop PWRs, and the rated power output was set at 890 MW. As for the turbine, TC6F-40 in was adopted. As the improved design, a large reactor containment vessel, 17 x 17 type 9-grid fuel, improved steam generators, a reactor vessel cover of one-body type, ...

International Nuclear Information System (INIS)

The UTST (University of Tokyo Spherical Tokamak) device was constructed for the purpose of exploring the formation of ultra-high beta ST (Spherical Tokamak) plasma using the double null plasma merging method. When two plasmas merge together to form a single plasma, magnetic field lines reconnect, and the magnetic field energy is converted to the plasma kinetic energy, increasing the plasma beta. The merging start-up has been demonstrated in the TS-3/4, START and MAST devices using coils inside the vacuum vessel and TS-3 plasma obtained 50% beta. In order to demonstrate the start-up in a more reactor relevant situation, UTST has all poloidal field coils outside the vacuum vessel. The first plasma experiment on the UTST was performed from December, 2007. In the result, the plasma obtained 10 kA by using only outer PF coils and single ST was generated at the lower area (z=-0.3 - -1.0[m]) close to a washer gun. This result suggests that another ...

International Nuclear Information System (INIS)

The Fast Flux Test Facility (FFTF) is a liquid-metal-cooled test reactor located on the Hanford Site. The FFTF is the only reactor of this type designed and operated with the intent of meeting the licensing requirements of the Nuclear Regulatory Commission (NRC). Unique characteristics of the FFTF that present special challenges related to leak rate testing include thin wall containment vessel construction, cover gas systems that penetrate containment, and a low-pressure design basis accident. The successful completion in 1986 of the third FFTF Integrated Leak Rate Test (ILRT) five days ahead of schedule and 10% under budget was a major achievement for the Westinghouse Hanford Company. The success of this operational safety test was due in large part to a special local area network (LAN) of three IBM PC/XT computers that monitored the sensor data, calculated the containment vessel leak rate, and displayed test results. The multiple computer ...

International Nuclear Information System (INIS)

In an existent emergency reactor core cooling device, if a ruptures should occure in a pipeline of a gravitational dropping type reactor core cooling system pool (GDCS) due to some or other causes, a portion of GDCS pool water was flown out of the ruptured port and could not be used for reactor core cooling. Then, a difference pressure detector is disposed to a GDCS pipeline at the inlet of a reactor pressure vessel. When it is judged by the detector, that coolants flow to the outside of the injection pipeline, an injection value disposed to the GDCS pipeline is closed by the difference pressure signal. Even if a rupture should occur on the side of the pressure vessel at downstream to the check value of the GDCS pipeline, since backflow is caused at the pressure container inlet of the GDCS pipeline with the rupture port, the rupture is detected by the difference pressure detector to close the injection valve. Therefore, loss of the GDCS pool ...

International Nuclear Information System (INIS)

BWRs are so designed that the exhaust steam from main steam safety relief valves is led to pressure suppression pools, and the steam is condensed in pool water, but at this time, dynamic load seems to arise in the pool water. In Tokai No. 2 Power Station, a Mark-2 containment vessel was adopted to improve the reliability as much as possible and to obtain the design with margin. In this report, the result of actual machine test in Tokai No. 2 Power Station and the method of reducing the load are described. When a relief valve works, the discharge of water in exhaust pipes into a suppression pool, the exhaust of air in exhaust pipes and repeated expansion and contraction of bubbles in pool water, and the exhaust of steam and condensation occur. As for the construction of the suppression pool in Tokai No. 2 Power Station, cross-shaped quencher and the structure with jet deflector were installed. The test plan and the test result with an actual machine are reported. ...