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Sample records for quiste epidermoide testicular

  1. Quiste epidermoide testicular bilateral en un paciente pediátrico con síndrome de Klinefelter / Bilateral epidermoid testicular cyst in an infant with Klinefelter´s syndrome

    Scientific Electronic Library Online (English)

    J.M., Alapont Alacreu; C., Domínguez Hinarejos; A., Serrano Durbá; F., Estornell; M., Martínez Verduch; F., Vera Sempere; F., Moreno; F., García Ibarra.

    2003-10-01

    Full Text Available Los quistes epidérmicos testiculares son lesiones muy infrecuentes en la edad infantil (3% de todas las tumoraciones testiculares). Sólo se ha descrito su aparición bilateral en la edad pediátrica en 2 observaciones y ninguna de ellas asociada a síndrome de Klinefelter. Presentamos, en este sentido, [...] el primer caso en nuestro conocimiento de quiste epidérmico bilateral testicular asociado a síndrome de Klinefelter en un niño, destacando el manejo y la conducta terapéutica realizada analizando asimismo las distintas pautas de tratamiento propuestas. Abstract in english Epidermoid cysts of the testis are rare in children (3% of all the testicular tumors). Bilateral appearance has only been described in the pediatric age in 2 cases and none associated to Klinefelter´s syndrome. We present, for our knowledge, the first case of bilateral epidermoid testicular cyst ass [...] ociated to klinefelter´s syndrome in a boy, highlighting its management and therapeutic approach. We analyze the different kinds of treatment.

  2. Testicular epidermoid cyst

    Directory of Open Access Journals (Sweden)

    Basri Çakiroglu

    2015-01-01

    Full Text Available Epidermoid cyst of the testis is a benign, non-teratomatous tumour. It is often possible to make the diagnosis pre-operatively, combining typical sonographic features with normal biochemical tumour markers. The accurate pre-operative diagnosis will allow for testis-sparing surgery and prevent unnecessary orchiectomy. An 11-year-old boy with testicular epidermoid cyst who presented with pain in testis was presented in this report.

  3. Quiste epidermoide del ciego / Epidermoid cyst of the cecum

    Scientific Electronic Library Online (English)

    Wataru, Yamanaka; Fernando, Llamosas B; Hugo, Adorno R.

    2012-02-01

    Full Text Available Quiste epidermoide es un saco con características benignas que se origina del ectodermo embrionario. Histológicamente consiste en una delgada capa de epitelio escamoso. Quistes epidermoide de ciego son excepcionalmente raros. Reportamos un caso de quiste epidermoide en pared anterior del ciego en un [...] a paciente sin cirugía previa y realizamos una revisión de lo publicado sobre esta patología. Abstract in english Epidermoid cyst is a sac with benign characteristic that originates from embrionary ectoderm. Histologically consists in a thin layer of squamous epithelium. Epidermoid cyst of the cecum are exceptionally rare. We report a case of an epidermoid cyst arising in the anterior wall of the cecum, in a wo [...] man with no previous history of surgery, and review of the literature are presented.

  4. Testis-sparing surgery in testicular mass: Testicular epidermoid cysts

    OpenAIRE

    Mahdavi-Zafarghandi, Reza; Shakiba, Behnam; Ameli, Mojtaba

    2014-01-01

    We present 3 patients with testicular epidermoid cysts who experienced testis-sparing surgery. These patients had a palpable painless testicular mass and underwent inguinal testicular exploration. Intraoperative frozen section revealed no evidence of malignancy and therefore enucleation of the tumour was performed. We demonstrate that careful intraoperative frozen-section examination helps to avoid unnecessary orchidectomy in testicular epidermoid cysts.

  5. Quiste epidermoide supraselar con rotura intraventricular: caso clínico / Suprasellar epidermoid cyst with intraventricular rupture: case report

    Scientific Electronic Library Online (English)

    Francisco, Rojas-Zalazar; Karin, Müller-Campos.

    2012-12-01

    Full Text Available Los quistes epidermoides son lesiones benignas en su mayoría, representando un 0,3 al 1,5% de los tumores intracraneanos y se originan por la inclusión de elementos epiteliales en el momento del cierre del tubo neural. Su presentación clínica está dada por compresión de estructuras adyacentes y con [...] menor frecuencia secundaria a la rotura espontánea causando meningitis química. Se presenta el caso clínico de un paciente de 34 años de sexo masculino que debuta con un cuadro de cefalea ictal y signos de irritación meníngea. La Tomografía computada de cerebro muestra una lesión hipodensa supraselar con signos de rotura hacia el sistema ventricular. La Resonancia Nuclear Magnética muestra una lesión predominantemente hipointensa en T1 e hiperintensa en T2 planteándose entre los diagnósticos posibles un quiste epidermoide. El paciente es operado y la biopsia informa un quiste epidermoide. La rotura de los quistes epidermoide hacia el espacio subaracnoideo o al ventrículo ocurre de forma espontánea, presentándose clínicamente con un síndrome meníngeo y puede ser causa de gran morbilidad. La rotura hacia el ventrículo es una presentación clínica descrita con poca frecuencia en la literatura. Abstract in english Epidermoid cyst are benign lesions representing 0,3-1,5% of intracranial tumors. They originate from inclusions of epithelials cells during closure of neural tube. Symptoms result from compression of adjacent structures or rarely due to rupture causing Chemical meningitis. In this report, we present [...] the case of a 34 years old male with history of ictal headache and meningeal signs. Brain CT showed hypodense suprasellar lesion with signs of rupture into the ventricular system. MRI showed a hypointense lesion on T1 and hyperintense on T2, suspecting epidermoid tumor. The Patient was operated and the sample demonstrated an epidermoid cyst. Spontaneous cyst rupture and spillage of the content into subarachnoid space or ventricles manifest as meningeal syndrome and cause high morbidity. Cyst rupture into de ventricle is infrequently described in literature.

  6. Clitoromegalia: quiste epidermoide de clítoris / Clitoromegaly: epidermal cyst of clitoris

    Scientific Electronic Library Online (English)

    Carlos, Ramírez-Isarraraz; Abner, Santos-López; Jaime, Cevallos-Bustillos; Vicente, Miranda-Sevilla.

    2013-12-01

    Full Text Available Objetivo: Describir un caso de clitoromegalia en una mujer perimenopáusica. Lugar: Centro de Tercer Nivel de Atención. Intervenciones: Resonancia magnética, ultrasonido pélvico, marcadores tumorales, clitoroplastia con resección quirúrgica de quiste epidermoide. Resultados: Clitoroplastia más resecc [...] ión de tumor epidermoide con preservación de la anatomía y sensibilidad. Conclusión: Paciente femenina de 52 años, sin antecedentes de trauma pélvico, quien desarrolló un caso inusual de clitoromegalia sin dolor u otros síntomas, además de un notorio crecimiento tumoral en los últimos cuatro años en el cual la malignidad fue descartada. Hay pocos casos de quistes epidermoides en ausencia de trauma o mutilación de genitales reportados en la literatura; generalmente son solitarios, de crecimiento lento y asintomáticos, localizados usualmente en la piel, el cuello o el tronco del clítoris. El procedimiento realizado fue una clitoroplastia con resección del quiste epidermoide, en el cual se ha preservado tanto la anatomía como la sensibilidad sin complicaciones después de seis meses de seguimiento. Abstract in english Objective: Describe a case of clitoromegaly in a perimenopausal female. Setting: Third Level Attention Center. Interventions: Magnetic resonance imaging, pelvic ultrasound, tumoral markers, clitoroplasty with surgical extirpation of epidermal cyst. Results: Clitoroplasty with surgical extirpation of [...] epidermal cyst and preservation of the anatomy and sensitivity. Conclusions: A 52 years old female patient without history of pelvic trauma who developed an unusual case of clitoromegaly without pain nor any symptoms besides notorius tumor growing over past four years in which malignancy was discarded. There are very few epidermal cyst cases in the absence of trauma or genitalia mutilation reported in literature; they are usually solitary tumors, with slow growing and asymptomatic. Usually localized in clitoral scalp, neck or trunk. The performed procedure was a clitoroplasty with extirpation of an epidermal cyst, where has been well preserved the anatomy and sensitivity, without any complication after six months follow up.

  7. Epidermoid Cysts of Head and Neck Region: Case Series and Review of Literature / Quistes Epidermoides de Región Cabeza y Cuello: Serie de Casos y Revisión de la Literatura

    Scientific Electronic Library Online (English)

    S, Sunil; Neetu, Oommen; R, Rathy; V. R, Rekha; Divya, Raj; V. K, Sruthy.

    2014-09-01

    Full Text Available Los quistes epidermoides y dermoides son hamartomas localizados en el cuello, la cabeza o el tronco, por lo general visibles al nacer. En algunos casos, el examen médico cuidadoso puede ayudar a encontrar quistes epidermoides y dermoides. Existe cierta ambigüedad acerca de su patogenia exacta, postu [...] lando teorías disontogenéticas, traumáticas y anomalías del conducto tirogloso. Los quistes epidermoides histopatológicamente tienen una cápsula quística revestida con epitelio estratificado delgado. Aunque la escisión quirúrgica completa es su tratamiento, se han reportado complicaciones. Presentamos tres casos de quiste epidermoides en la región maxilofacial. Abstract in english Epidermoid and dermoid cysts are hamartomas localized on the neck, head, or trunk, usually visible at birth. In some instances, careful medical examination may help to find most epidermoid and dermoid cysts. Ambiguity about their exact pathogenesis exists and dysontogenetic, traumatic, and thyroglos [...] sal anomaly theories have been postulated. Histopathologically epidermoid cysts have a cystic capsule lined with thin stratified epithelium. Surgical excision though completes the treatment, complications have been reported. We report three cases of epidermoid cyst on the maxillofacial region.

  8. Testiste Epidermoid Kist

    OpenAIRE

    ÇA?LAR,, M.; B?LEN, C.Y.; BARI?, S.; YILMAZ, A. F.

    2010-01-01

    Epidermoid Cyst Of Testis Epidermoid cysts are rare, benign testicular masses representing less than 1 % of all testis tumors. Most epidermoid cysts are asymptomatic and detected and during routine physical or self examinations. Here we present a case with epidermoid cysts of the tesüs and discuss treatment alternatives. Epidermoid kist tüm testis tümörlerinin % l'i oran?nda görülen benign bir lezyondur. Ço?unlukla asemptomatiktir ve fizik muayene yada hastan?n kendisini incelemesi ...

  9. Carcinoma epidermoide sobre sinus pilonidal / Epidermoid carcinoma upon pilonidal sinus

    Scientific Electronic Library Online (English)

    J., Alecha Gil; M., Echenique-Elizondo; J. A., Amondarain; G., Górriz Arias.

    2006-05-01

    Full Text Available INTRODUCCIÓN: La degeneración maligna es una complicación rara observada principalmente en caso de enfermedad pilonidal crónica recurrente y se asocia con un muy mal pronóstico. MATERIAL Y MÉTODOS: Se han revisado 367 pacientes afectos de quiste pilonidal, bien simple o complicado. Entre ellos hemos [...] encontrado 3 casos (0,81%) de carcinoma epidermoide. CONCLUSIÓN: El carcinoma epidermoide de sinus pilonidal es una enfermedad infrecuente asociado a un muy mal pronóstico. Abstract in english INTRODUCTION: Malignant degeneration of pilonidal sinus is a rare complication observed mainly in recurrent chronic cases of the disease, associated to a very bad prognosis. MATERIAL AND METHODS: We have reviewed 367 patients with simple and complicated pilonidal cysts. We found 3 cases (0.81%) of e [...] pidermoid carcinoma. CONCLUSIONS: Pilonidal sinus epidermoid carcinoma is an infrequent disease predicting for very poor outcome.

  10. Benign Intratesticular Epidermoid Cyst of the Testis: Diagnostic Dilemma

    Directory of Open Access Journals (Sweden)

    Kishor H Suryawanshi

    2014-05-01

    Full Text Available Intratesticular epidermoid cysts of the testis are rare benign lesions, comprising about 1-2% of all the testicular neoplasms. Clinically it may not be differentiated reliably from the most common malignant testicular tumours and poses a diagnostic dilemma. Majority of the testicular tumours are malignant one, hence accurate diagnosis in benign lesions such as epidermoid cyst is always warranted to avoid unnecessary invasive procedures like orchidectomy. Herein, we present a case of benign, intratesticular epidermoid cyst of the testis in a 30 years old male treated by conservative approach with testicular preservation, avoiding unnecessary orchidectomy.

  11. Pineal epidermoid

    Science.gov (United States)

    Senapati, Satya B.; Mishra, Sudhansu S.; Patnaik, Ashis; Patra, Sunil K.

    2012-01-01

    Background: Tumors of pineal region are uncommon, accounting for ?1% of intracranial tumors in adults and 3–8% of pediatric brain tumors. Epidermoid cysts account for 0.2–1% of all intracranial tumors. The majority occur in and around the cerebellopontine angle and suprasellar area. Getting an epidermoid in pineal region is very rare. Case Description: We report a case of pineal epidermoid, which was diagnosed correctly as epidermoid depending on computed tomography (CT) and magnetic resonance imaging (MRI) findings. Knowing its benign nature, we accordingly planned for its near-total removal. Conclusion: Most cases of pineal tumors present as obstructive hydrocephalus. They either require pre- or postoperative ventriculoperitoneal (VP) shunt. If properly planned, many benign pineal tumors may be successfully excised and, most importantly, postoperative VP shunt could be avoided. PMID:23226611

  12. Quiste Tímico

    Scientific Electronic Library Online (English)

    IsnerioValerio, Arzuaga Anderson; María Victoria, López Soto; María de los Angeles, Ferrer Rodríguez; Lurdes, Palma Machado.

    2001-06-01

    Full Text Available Los quistes tímicos son lesiones poco frecuentes. La mayoría se presenta en las primeras décadas de la vida, aunque pueden estar presentes desde el nacimiento. Otros se descubren incidentalmente en radiografías torácicas y autopsias y pueden confundirse con tumores malignos. Se reporta 1 caso, con h [...] emorragia antigua y granulomas de colesterol, en el estudio necrópsico de una anciana de 71 años de edad, localizado en la porción anterosuperior del mediastino, no relacionado con su fallecimiento, el cual fue por infarto miocárdico agudo. El estudio histológico de la pieza reveló la naturaleza tímica del proceso. Se discuten los aspectos microscópicos del caso y se precisa su diagnóstico diferencial con otros tumores del mediastino Abstract in english Thymic cysts are uncommon lesions. Most of them occur in the first decade of life, although they may be present at birth. Other thymic cysts are incidentally discovered in chest X-rays and in autopsy and may be mistaken for malignant tumors. It is reported the case of a woman aged 71 with an old hem [...] orrhage and cholesterol granuloma detected by necropsy study, where a cyst was located in the mediastinum anteroposterior portion.. It was not related to her death, since she died from acute myocardial infarction. The histologic study of the cyst revealed the thymic nature of the process. The microscopic features of the case are discussed and its differential diagnosis is specified in relation to other mediastinal tumors

  13. Epidermoid cyst post dermofasciectomy.

    LENUS (Irish Health Repository)

    Henry, Francis P

    2010-01-01

    We report the finding of an unusual presentation of an epidermoid cyst 3 years following dermofasciectomy for Dupuytren\\'s disease. Epidermoid cysts remain a rare entity in the palmoplanter distribution but also a very unusual finding within the confines of a full thickness skin graft.

  14. Neuroradiological aspects of intracranial epidermoids

    International Nuclear Information System (INIS)

    Intracranial epidermoids are primarily extracerebral congenital cysts. Intra- and extradural types are differentiated: intradural lesions originate in the intracranial CSF spaces, and extradural lesions in the bony skull. Epidermoids increase in size passively as the results of an increase in the cyst volume and not because of active growth. Clinically epidermoids behave like benign, slow-growing cerebral tumours. Differential diagnosis includes other cysts and cystic tumours. Neuroradiologically epidermoids present as polycystic lesions showing extensive growth in the extracerebral CSF spaces and secondary invagination of the brain. On CT and MR, despite the high cholesterol content, epidermoids show the characteristics of liquor and not those of fat. It can be shown that he typical CT and MR appearance of an epidermoid is due to the different proportions of CSF in the cyst content, which results from diffusion of dehiscence of te cyst capsule. The present study was based on analysis of 6 cases selected from a total of 29 patients with CNS epidermoids. (orig.)

  15. Quistes de los maxilares

    Directory of Open Access Journals (Sweden)

    Ivan Alberto Manotas Arevalo

    2013-12-01

    Full Text Available Los Grandes Quistes de los Maxilares han estado vinculados siempre a la humanidad, desde tiempos remotos, pues han sido halladas en restos de especimenes fosiles, han llamado la atencion de los clínicos, en torno a su etiologia, en la que se ha introducido la participacion de la genetica, (demostrada en el desarrollo de los queratoquistes maxilares, la fisiopatologia, caracteristicas histologicas (inmunohistoquimica, posibilidades diagnosticas por la imagen, (como la tomografia computarizada y la resonancia nuclear magnetica y otras pruebas. Además llaman la atención al estudio, por sus alternativas de manejo especialmente las formas radicales, y el analisis de asociaciones a otras patolo-gias benignas y malignas, y de la recurrencia muy alto de algunas de estas lesiones. Mucho se ha desarrollado para elucidar su naturaleza real, estadificar adecuadamente la lesion descartando asocia-ciones patologicas sindromicas, indicar un tratamiento apropiado, y realizar seguimientos a largo plazo. Este articulo pretende recaudar una information general que de parametros para abordar el estudio de los quistes maxilares a partir de la presentacion de un caso clinico.

  16. Recurrent intramedullary epidermoid cyst of conus medullaris

    OpenAIRE

    Fleming, Christina; Kaliaperumal, Chandrasekaran; O’Sullivan, Michael

    2011-01-01

    Spinal intramedullary epidermoid cyst is a rare condition. Recurrent epidermoid cyst in the spine cord is known to occur. The authors describe a case of recurrent conus medullaris epidermoid cyst in a 24-year-old female. She initially presented at 7 years of age with bladder disturbance in the form of diurnal enuresis and recurrent urinary tract infection. MRI lumbar spine revealed a 4 cm conus medullaris epidermoid cyst. Since the initial presentation, the cyst had recurred seven times in th...

  17. Quiste óseo aneurismático

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    Ferdinando de Conto

    2012-06-01

    Full Text Available El quiste óseo aneurismático (QOA es una lesión benigna rara en huesos maxilares, su mayor frecuencia es en huesos largos del esqueleto y columna vertebral. Algunos autores especulan que el origen sea por trauma, mala formación o un neoplasma. El aspecto radiográfico puede mostrar desde una imagen difusa hasta una imagen bien definida, muy semejante a las otras lesiones de los maxilares volviendo el diagnóstico diferencial amplio. Con la destrucción del córtex óseo puede todavía formar una imagen reaccional del periostio en forma de rayos de sol, característico de una lesión maligna. En este estudio, se presenta caso de paciente femenino, 17 años de edad, que buscó el Servicio de Cirugía y Traumatología Buco maxilofacial del Hospital São Vicente de Paulo-RS, que presentó dolor y aumento de volumen en la mandíbula. Informó que hace cerca de un año empezó a sentir malestar en la región junto al ángulo mandibular derecho, lo cual fue progresivamente aumentando de volumen. El aspecto radiográfico acordaba una lesión maligna. Después de la confirmación histopatológica de QOA, el tratamiento seleccionado para el caso fue quirúrgico conservador, con legrado de la cavidad ósea, y fue mantenido en control posoperatorio de rutina con 6 y 18 meses. En las radiografías panorámicas realizadas se verifica la neoformación ósea y cura del caso.

  18. Quiste coloide del tercer ventrículo

    Scientific Electronic Library Online (English)

    Juan, Dávila Meneses.

    2012-09-01

    Full Text Available Los quistes coloides son lesiones intracraneales con una incidencia calculada en tres individuos por millón de personas en un año. Son tumores benignos de la porción anterosuperior del tercer ventrículo. El flujo normal del líquido cefalorraquídeo puede ser interrumpido por un gran quiste que obstru [...] ya el foramen de Monro. Los signos y síntomas asociados engloban un espectro amplio de características, desde una cefalea no específica hasta datos de hipertensión intracraneal; algunos quistes coloides se dan en el comienzo agudo de una hidrocefalia y pueden llevar a una muerte súbita. Caso: presentamos el caso de un adolescente masculino de 13 años de edad, de raza negra, quien dos días antes de su fallecimiento había manifestado cefalea. Al examen de autopsia se evidenció un quiste coloide del tercer ventrículo que produjo una hidrocefalia aguda obstructiva, con edema cerebral severo y herniación de amígdalas cerebelosas. En este artículo comentamos las características principales del quiste coloide y realizamos una breve revisión bibliográfica Abstract in english Colloid cysts are intracranial lesions with an estimated incidence of three individuals per million people per year. They are benign tumors of the anterior portion of the third ventricle. The normal flow of cerebrospinal fluid may be interrupted by a large cyst obstructing the foramen of Monro. The [...] signs and symptoms associated cover a wide range of features, from a non-specific headaches to intracranial hypertension data, some colloid cysts occur in the acute onset of hydrocephalus and can lead to sudden death. Case: We present the case of an adolescent male 13 years of age, black race, who two days before his death had expressed headache. On examination autopsy showed a third ventricular colloid cyst that caused acute obstructive hydrocephalus with severe cerebral edema and herniation of cerebellar tonsils. In this article we discuss the main features of the colloid cyst and performed a brief literature review

  19. Quiste coloide del tercer ventrículo

    Directory of Open Access Journals (Sweden)

    Juan Dávila Meneses

    2012-09-01

    Full Text Available Los quistes coloides son lesiones intracraneales con una incidencia calculada en tres individuos por millón de personas en un año. Son tumores benignos de la porción anterosuperior del tercer ventrículo. El flujo normal del líquido cefalorraquídeo puede ser interrumpido por un gran quiste que obstruya el foramen de Monro. Los signos y síntomas asociados engloban un espectro amplio de características, desde una cefalea no específica hasta datos de hipertensión intracraneal; algunos quistes coloides se dan en el comienzo agudo de una hidrocefalia y pueden llevar a una muerte súbita. Caso: presentamos el caso de un adolescente masculino de 13 años de edad, de raza negra, quien dos días antes de su fallecimiento había manifestado cefalea. Al examen de autopsia se evidenció un quiste coloide del tercer ventrículo que produjo una hidrocefalia aguda obstructiva, con edema cerebral severo y herniación de amígdalas cerebelosas. En este artículo comentamos las características principales del quiste coloide y realizamos una breve revisión bibliográficaColloid cysts are intracranial lesions with an estimated incidence of three individuals per million people per year. They are benign tumors of the anterior portion of the third ventricle. The normal flow of cerebrospinal fluid may be interrupted by a large cyst obstructing the foramen of Monro. The signs and symptoms associated cover a wide range of features, from a non-specific headaches to intracranial hypertension data, some colloid cysts occur in the acute onset of hydrocephalus and can lead to sudden death. Case: We present the case of an adolescent male 13 years of age, black race, who two days before his death had expressed headache. On examination autopsy showed a third ventricular colloid cyst that caused acute obstructive hydrocephalus with severe cerebral edema and herniation of cerebellar tonsils. In this article we discuss the main features of the colloid cyst and performed a brief literature review

  20. Epidermoid Cyst of the Cecum

    Science.gov (United States)

    Park, Jae-Young; Kim, Youn Wha; Lee, Kil Yeon

    2015-01-01

    An epidermoid cyst of the cecum is extremely rare; only eight cases have been reported in the literature. A 63-year-old woman was admitted to Kyung Hee University Medical Center with a colonic mass that had been discovered incidentally during a regular health check-up. The radiographic impression was that this mass was a gastrointestinal stromal tumor. During surgery, an exophytic mass in the cecal wall was resected by using an ileocecectomy. Based on the macroscopic and the microscopic findings, this case was identified as an epidermoid cyst of the cecal wall. We report this case to discuss the origin of this entity and the unusual nature of our case. PMID:25745626

  1. Recidiva tardía de carcinoma epidermoide de pene / Epidermoid pennis carcinoma recidive

    Scientific Electronic Library Online (English)

    E., Sanz Mayayo; R., Rodríguez-Patrón Rodríguez; I., Gómez García; D., García Ortells; R., García Navas; R., García González; Á., Escudero Barrilero.

    2003-12-01

    Full Text Available OBJETIVO: Presentar un caso de recidiva de carcinoma epidermoide de pene a los 21 años de la cirugía. MÉTODO: Se trata de un paciente de 85 años con antecedentes de penectomía parcial por carcinoma epidermoide, que presenta lesión excrecente a nivel de glande de 1 mes de evolución. Se biopsia siendo [...] el resultado carcinoma epidermoide por lo que se realiza penectomía total con uretrostomía cutánea. RESULTADO: El estudio histopatológico de la pieza confirmó un carcinoma epidermoide bien diferenciado. Abstract in english OBJETIVE: We report a recidive of pennis carcinoma after 21 years of surgery. METHODS: This is the case of a male of 85 years old, with parcial penectomy; by epidermoid carcinoma. In phisics exploration, that it displays excrecente lesion at level of glande of 1 month of evolution. Biopsy being the [...] result of epidermoid carcinoma reason why is made. Total penectomy, a with cutaneus uretrostomy. RESULTS: The histopathological study of the piece, confirm a epidermoid carcinoma well differentiated.

  2. Quiste residual gigante: presentación de un caso

    Directory of Open Access Journals (Sweden)

    Oscar Rivero P\\u00E9rez

    2014-01-01

    Full Text Available Fundamento: u n quiste es una estructu ra con tendencia a la forma redondeada, constituida por una pared externa de tejido conectivo fibroso, una pared interna formada por un tapiz epitelial. La cavidad quística contiene un material líquido o semilíquido de color cetrino que, cuando se infecta, se convierte en purulento y carmelitoso. El quiste residual puede haber sido anteriormente un quiste lateral o un quiste apical y al haberse extraído el diente, a par tir de cuyo periodonto se forma el quiste , se queda en el tejido óseo sin haber sido exti rpado. Objetivo: presentar un caso al cual se le diagnosticó y trató un quiste residual mandibular que abarcaba la hemiarcada izquierda, que permitió restablecer las funciones masticatorias y estética. Caso Clínico: paciente que fue atendido en la consult a de Cirugía Maxilofacial de la Facultad de Estomatología de Camagüey , con un aumento de volumen en la región lateral izquierda, con antecedentes de trauma anterior que le provocó fractura de mandíbula. Se describen las características clínicas de la enfer medad y el tratamiento quirúrgico realizado, se utilizó para el mismo los principios de la técnica de enucleación . 577 Conclusiones: a unque se han reportados pocos c asos en la l iteratura nacional y extranjera, estos han sido quiste s de menor tamaño que inclu yen uno o dos dientes, no existen reportes de quistes residuales que involucren toda la arcada o hemiarcada dentaria. Se obtuvieron resultados estéticos satisfactorios con la técnica quirúrgica empleada y no se presentaron complicaciones.

  3. Dev sublingual epidermoid kist: Olgu sunumu

    OpenAIRE

    Yüce, Salim; Polat, Kerem; Uysal, ?smail Önder; Bekar, Abuzer; Müderris, Suphi

    2013-01-01

    Epidermoid and dermoid cysts are benign lesions, that can be seen in different parts of the body. They are seen in oral cavity about 1.6% and are very rare in oral cavity cysts. We presented our case with a giant sublingual epidermoid cyst, a rarely seen pathology with a literature review.

  4. Testicular Injuries

    Science.gov (United States)

    ... are protected. When you're exercising or playing sports, make sure that using protective gear is part of your routine and you'll be able to play hard without fear of testicular injury! Reviewed by: T. Ernesto Figueroa, ...

  5. Neuroradiological aspects of intracranial epidermoids; Zur neuroradiologischen Diagnostik der intrakraniellen Epidermoide

    Energy Technology Data Exchange (ETDEWEB)

    Hagen, T. [Universitaetskliniken des Saarlandes, Homburg/Saar (Germany). Inst. fuer Neuroradiologie; Kujat, C. [Universitaetskliniken des Saarlandes, Homburg/Saar (Germany). Inst. fuer Neuroradiologie; Donauer, E. [Universitaet des Saarlandes, Homburg/Saar (Germany). Neurochirurgische Klinik; Piepgras, U. [Universitaetskliniken des Saarlandes, Homburg/Saar (Germany). Inst. fuer Neuroradiologie

    1994-11-01

    Intracranial epidermoids are primarily extracerebral congenital cysts. Intra- and extradural types are differentiated: intradural lesions originate in the intracranial CSF spaces, and extradural lesions in the bony skull. Epidermoids increase in size passively as the results of an increase in the cyst volume and not because of active growth. Clinically epidermoids behave like benign, slow-growing cerebral tumours. Differential diagnosis includes other cysts and cystic tumours. Neuroradiologically epidermoids present as polycystic lesions showing extensive growth in the extracerebral CSF spaces and secondary invagination of the brain. On CT and MR, despite the high cholesterol content, epidermoids show the characteristics of liquor and not those of fat. It can be shown that he typical CT and MR appearance of an epidermoid is due to the different proportions of CSF in the cyst content, which results from diffusion of dehiscence of te cyst capsule. The present study was based on analysis of 6 cases selected from a total of 29 patients with CNS epidermoids. (orig.) [Deutsch] Intrakranielle Epidermoide sind primaer extrazerebrale kongenitale Zysten. Es sind intra- von extraduralen Formen zu unterscheiden. Intradurale Epidermoide entstehen in den intrakraniellen Liquorraeumen, extradurale im Schaedelknochen. Epidermoide vergroessern sich nicht aktiv durch autonomes Wachstum, sondern passiv durch Zunahme des Zysteninhalts. Klinisch verhalten sie sich wie gutartige, langsam wachsende Hirntumoren. Differential-diagnostisch sind sie gegenueber anderen Zysten und zystischen Tumoren abzugrenzen. Neuroradiologisch sind Epidermoide durch ihre polyzyklische Konfiguration und ihre extensive Ausdehnung in den extrazerebralen Liquorraeumen mit sekundaerer Invagination in das Gehirn gekennzeichnet. Im MR und im CT stellen sich Epidermoidzysten trotz des hohen Gehaltes an Cholesterin nicht fett-, sondern liquoraequivalent dar. Es kann nachgewiesen werden, dass die Ursache fuer die Abbildungseigenschaften der Epidermoide in einer unterschiedlichen transmuralen Beimengung von Liquor cerebrospinalis zum Zysteninhalt liegt. Die Studie basiert auf der Analyse von 6 Faellen, die aus einem Gesamtkollektiv von 29 Patienten mit Epidermoiden des Zentralnervensystems ausgewaehlt wurden. (orig.)

  6. Quiste de colédoco tipo IV A

    Directory of Open Access Journals (Sweden)

    Lucas Esteban Granero

    2009-01-01

    Full Text Available El quiste de colédoco tipo IV A es una enfermedad muy poco común caracterizada por una dilatación quística congénita del árbol biliar que se extiende también a los canalículos biliares intrahepáticos. Se comunica el caso de una mujer de 19 años de edad con ictericia y dolor abdominal. La paciente fue sometida a una amplia evaluación clínica, analítica y por imágenes. La tomografía computada y la colangiopancreatografía por resonancia magnética revelaron un quiste coledociano de 13.5 cm con compromiso intrahepático. Se combinó la resección de la parte extrahepática del quiste con una hepaticoyeyunoanastomosis en Y de Roux. Se descubrió una estructura ductal en la parte distal del quiste extrahepático. No hubo complicaciones perioperatorias ni alejadas en el seguimiento.

  7. Quiste dermoide del suelo de la boca

    Directory of Open Access Journals (Sweden)

    Ayelén María Portelles Massó

    2010-12-01

    Full Text Available El quiste dermoide representa menos del 0,01 % de todos los quistes de la cavidad bucal. Su ubicación más frecuente es en suelo de boca. Se presenta el caso de una paciente femenina de 19 años de edad que hacía aproximadamente 7 años había notado un aumento de volumen debajo de la lengua, el cual le crecía paulatinamente y ya se apreciaba por fuera de la cara. Además, le ocasionaba molestias al hablar y al masticar. Se realizaron estudios complementarios y bajo anestesia general nasotraqueal. Se procedió a su exéresis quirúrgica mediante un abordaje intrabucal, donde se obtuvieron excelentes resultados estéticos y funcionales. El diagnóstico histopatológico se correspondió con un quiste dermoide de suelo de boca. La paciente no ha tenido recurrencia de la lesión transcurridos tres años de la operación. El quiste dermoide de suelo de boca se presenta como una tumoración benigna de la línea media. La exéresis intrabucal demuestra beneficios estéticos y funcionales.

  8. Recurrent intramedullary epidermoid cyst of conus medullaris.

    LENUS (Irish Health Repository)

    Fleming, Christina

    2011-01-01

    Spinal intramedullary epidermoid cyst is a rare condition. Recurrent epidermoid cyst in the spine cord is known to occur. The authors describe a case of recurrent conus medullaris epidermoid cyst in a 24-year-old female. She initially presented at 7 years of age with bladder disturbance in the form of diurnal enuresis and recurrent urinary tract infection. MRI lumbar spine revealed a 4 cm conus medullaris epidermoid cyst. Since the initial presentation, the cyst had recurred seven times in the same location and she underwent surgical intervention in the form of exploration and debulking. This benign condition, owing to its anatomical location, has posed a surgical and overall management challenge. This occurrence is better managed in a tertiary-care centre requiring multi-disciplinary treatment approach.

  9. Testicular Exams

    Science.gov (United States)

    ... play your goals. Hot Topics Vitamins and Minerals Body Dysmorphic Disorder Dealing With Anger Meningitis Writing a Paper Testicular Exams KidsHealth > Teens > Sexual Health > For Guys > ... the doctor is interested in finding out specific things about your body and your health. He or she will check ...

  10. Testicular Cancer

    Science.gov (United States)

    ... of skin behind the penis. You can get cancer in one or both testicles. Testicular cancer mainly affects young men between the ages of ... undescended testicle Have a family history of the cancer Symptoms include pain, swelling, or lumps in your ...

  11. Quiste suprarrenal primario / Primary adrenal cyst

    Scientific Electronic Library Online (English)

    Patricio, Cabané T; Patricio, Gac M; Jorge, Mariño B; Daniela, Ibacache A; Alejandra, Ledezma S; Claudia, Morales H.

    2011-12-01

    Full Text Available Los quistes suprarrenales son las lesiones quísticas más frecuentes de la glándula suprarrenal, a pesar de que constituyen una rara entidad. Típicamente se presentan por un cuadro de dolor abdominal o masa palpable, pero en la actualidad se detectan cada vez con más frecuencia en estudios radiológic [...] os como incidentalomas. Los quistes suprarrenales cuentan con amplios diagnósticos diferenciales, lo que hace un difícil diagnóstico definitivo y una dificultad en el manejo posterior. Estos quistes se clasifican en cuatro subtipos: endoteliales, pseudoquiste, epiteliales y parasitarios. El manejo de un quiste suprarrenal se puede resumir en tres pilares fundamentales: descartar el estado funcional del quiste, evaluación de eventual malignidad por imágenes, y evitar las posibles complicaciones (hemorragia, infección), sobre todo en los quistes de gran tamaño. Se presenta el caso de una paciente con quiste suprarrenal izquierdo no funcionante asociado a dolor abdominal. Se realiza revisión de la literatura y se plantean los distintos diagnósticos y alternativas terapéuticas. Abstract in english Adrenal cyst is the commonest type of benign lesions of adrenal gland, althought is a very rare entity. Tipically, they are presented with abdominal pain or palpable mass, but nowdays they are detected most frecuently an imaging studies like incidentaloma. Adrenal Cyst have a broad differential diag [...] noses, rendering definitive diagnosis and subsequent management difficult. Are categorized into four subtypes: endothelial, pseudocyst, epithelial, and parasitic. This management paradigm may be summarized as: ruling out functional status of the cyst, evaluating chances of incidental malignancy by imaging, avoiding potential complications of surveillance (hemorrhage, infection), particularly in large cysts. A case of a patient with a left non-functioning adrenal cyst is reported, with abdominal pain. The diagnostic and therapeutic options are discussed and the literature is reviewed.

  12. Quiste suprarrenal primario Primary adrenal cyst

    Directory of Open Access Journals (Sweden)

    Patricio Cabané T

    2011-12-01

    Full Text Available Los quistes suprarrenales son las lesiones quísticas más frecuentes de la glándula suprarrenal, a pesar de que constituyen una rara entidad. Típicamente se presentan por un cuadro de dolor abdominal o masa palpable, pero en la actualidad se detectan cada vez con más frecuencia en estudios radiológicos como incidentalomas. Los quistes suprarrenales cuentan con amplios diagnósticos diferenciales, lo que hace un difícil diagnóstico definitivo y una dificultad en el manejo posterior. Estos quistes se clasifican en cuatro subtipos: endoteliales, pseudoquiste, epiteliales y parasitarios. El manejo de un quiste suprarrenal se puede resumir en tres pilares fundamentales: descartar el estado funcional del quiste, evaluación de eventual malignidad por imágenes, y evitar las posibles complicaciones (hemorragia, infección, sobre todo en los quistes de gran tamaño. Se presenta el caso de una paciente con quiste suprarrenal izquierdo no funcionante asociado a dolor abdominal. Se realiza revisión de la literatura y se plantean los distintos diagnósticos y alternativas terapéuticas.Adrenal cyst is the commonest type of benign lesions of adrenal gland, althought is a very rare entity. Tipically, they are presented with abdominal pain or palpable mass, but nowdays they are detected most frecuently an imaging studies like incidentaloma. Adrenal Cyst have a broad differential diagnoses, rendering definitive diagnosis and subsequent management difficult. Are categorized into four subtypes: endothelial, pseudocyst, epithelial, and parasitic. This management paradigm may be summarized as: ruling out functional status of the cyst, evaluating chances of incidental malignancy by imaging, avoiding potential complications of surveillance (hemorrhage, infection, particularly in large cysts. A case of a patient with a left non-functioning adrenal cyst is reported, with abdominal pain. The diagnostic and therapeutic options are discussed and the literature is reviewed.

  13. Testicular varicoceles

    Energy Technology Data Exchange (ETDEWEB)

    Beddy, P. [Department of Radiology, Adelaide and Meath Hospital, Tallaght, Dublin 24 (Ireland); Geoghegan, T. [Department of Radiology, The Adelaide and Meath Hospital, Tallaght, Dublin 24 (Ireland); Browne, R.F. [Department of Radiology, The Adelaide and Meath Hospital, Tallaght, Dublin 24 (Ireland); Torreggiani, W.C. [Department of Radiology, The Adelaide and Meath Hospital, Tallaght, Dublin 24 (Ireland)]. E-mail: william.torreggiani@amnch.ie

    2005-12-15

    A testicular varicocele represents an abnormal degree of venous dilatation of the pampiniform plexus. It is a relatively common condition and may present at scrotal pain and swelling. An association with male subfertility is an area of debate. This article describes the present day radiological criteria and imaging techniques to aid accurate diagnosis of varicoceles. In addition, the role of the interventional radiologist in treating this condition is discussed.

  14. Testicular lymphoma

    DEFF Research Database (Denmark)

    Møller, Michael Boe; d'Amore, F; Christensen, Bjarne Egelund

    1994-01-01

    In a Danish population-based non-Hodgkin's lymphoma registry, 2687 newly diagnosed patients were registered from 1983 to 1992. 39 had testicular involvement (TL) (incidence 0.26/10(5)/year). Median age was 71 years. 24 cases had localised and 15 had disseminated disease. Histologically, all cases were diffuse (65% diffuse centroblastic type). Of the 27 tested, 11% were of T- and 89% of B-immunophenotype. In localised cases, where surgery was supplemented by combination chemotherapy (CCT), the re...

  15. Testicular tumors

    International Nuclear Information System (INIS)

    The decision to perform CT or lymphangiography should be based upon the anticipated method of treatment. In some cases, ultrasonography may be an acceptable alternative primary abdominal imaging method. In addition, ultrasonography may play an important role in the detection of occult testicular neoplasms in patients who have metastatic disease and a normal scrotal examination. Intravenous urography and inferior vena cavography are insensitive methods for the detection of retroperitoneal lymphadenopathy and need not be used routinely for staging. Because the lungs are the major extralymphatic site of metastases in patients with testicular neoplasms some form of chest imaging should be performed in all patients. In this regard, CT has proved more sensitive than full chest tomography for the detection of both pulmonary and mediastinal metastases. Radioimmunoassays for serum alpha-fetoprotein (AFP) and the beta subunit of human chorionic gonadotropin (beta-HCG), although they fall outside the domain of radiology, are discussed because of their importance in the clinical staging and management of testicular tumors

  16. Carcinoma papilar de tiroides en quiste tirogloso

    Scientific Electronic Library Online (English)

    JULIÁN ANDRÉS, MOLANO G; GONZALO, ROSSEL DE LA M; MIGUEL, GONZÁLEZ P; INGRID, PLASS DEL C.

    2013-06-01

    Full Text Available Objetivo: Reportar un caso raro de carcinoma papilar en un quiste tirogloso y discutir su manejo. Paciente y Método: Un hombre de 72 años a quien se realizó un diagnóstico clínico de un quiste tirogloso, fue llevado a una cirugía de Sistrunk's y luego una tiroidectomía total ante la evidencia de cán [...] cer papilar en el quiste tirogloso. Resultados: El examen histopatológico reveló un carcinoma papilar de tiroides en el quiste tirogloso y la glándula tiroides fue normal, el paciente permaneció libre de enfermedad en su seguimiento. Conclusiones: La mayoría de los cánceres que surgen en quiste del conducto tirogloso son de bajo riesgo, y el procedimiento Sistrunk's con una tiroidectomía total es un tratamiento adecuado para este tipo de cáncer. Abstract in english Papillary carcinoma in thyroglossal duct cyst Background: To report a rare case of papillary carcinoma in thyroglossal duct cyst and discuss its management. Material and Method: A 72 year-old man was clinically diagnosed to have a big thyroglossal duct cyst. Sistrunk's procedure followed by total th [...] yroidectomy on the evidence of papillary cancer in thyroglossal duct cyst. Results: Histopathologic examination revealed a papillary carcinoma in the thyroglossal duct cyst and normallity in the thyroid gland. The patient remained free of disease on follow-up. Conclusion: Most cancers arising in thyroglossal duct cyst are of low risk, and Sistrunk's procedure with a total thyroidectomy is an adequate treatment for such cancers.

  17. QUISTE MESENTERICO COMO CAUSA DE ABDOMEN AGUDO

    Scientific Electronic Library Online (English)

    Ana María, Caballero Arévalo; Roberto Carlos, Ríos García; David Carlos, Ramírez López.

    Full Text Available Los quistes mesentéricos son tumores abdominales de asiento en el intestino delgado se originan de los leiomiomas yeyunales que en su evolución desarrollan un quiste mesenterio gigante, o puede ser un tumor primario originado en las hojas mesentéricas constituyen una patología poco frecuente en el a [...] dulto, la causa es un defecto en el desarrollo de los linfáticos mesentéricos, existiendo espacios cerrados en los que se acumula contenido linfático. Los quistes mesentéricos son tumores abdominales benignos poco frecuentes de etiología aún no determinada ocurren en cualquier edad, son causa de abdomen agudo, obstrucción intestinal y el 3% se puede malignizarse. Presentamos el caso de un paciente de sexo masculino de 72 años con abdomen agudo secundario a quiste mesenterio. Abstract in english The Mesenteric cysts are abdominal tumors that develop in thin intestine, they origin from yayunal leiomiomas that in their evolution develop a giant mesenteric cyst, or it can be a primary tumor originated in the mesenteric leafs. They constitute a not very frequent pathology in adults the cause is [...] a defect in the development of mesenteric lymphatics, existing closed spaces in which accumulates lymphatic content. The mesenteric cysts are not very frequent benign abdominal of uncertain etiologv, they appear at any age. they are cause of abdomen pain, intestinal obstruction and 3 % of them can become malignant. We present the case of a masculine sex patient of 72 years old with secondary abdomen pain to cyst mesenteric.

  18. General Information about Testicular Cancer

    Science.gov (United States)

    ... Testicular Cancer Screening Testicular Cancer Treatment (PDQ®) General Information About Testicular Cancer Key Points Testicular cancer is ... the PDQ Adult Treatment Editorial Board . Clinical Trial Information A clinical trial is a study to answer ...

  19. Carcinoma epidermoide en condilomatosis vulvoperineal gigante

    Scientific Electronic Library Online (English)

    Ana, Lizcano; Dulce, Puente; Jesus, Tata; Janette, Sholz; Jorge, Bittar.

    2006-12-01

    Full Text Available La condilomatosis vulvoperineal es una entidad muy frecuente en mujeres en edad reproductiva; recomendándose realizar la tipificación del virus papiloma humano, dada la relación de algunos subtipos con el carcinoma epidermoide a nivel ginecológico. Se presenta el caso de una paciente femenina de 39 [...] años que consultó por presentar una lesión exofítica, verrugosa que ocupa labios mayores y menores de la vulva, clítoris, introito vaginal y región perianal; de la cual se toma biopsia incisional reportando papilomatosis por virus papiloma humano, sin evidencia de atipias. Se lleva a quirófano realizando dermovulvectomía, cuya biopsia definitiva reportó carcinoma epidermoide invasor bien diferenciado, focal, con bordes resección libres; se completa con disección inguinal bilateral superficial y profunda sin evidencia de lesión metastásica ganglionar. Se realizó tipificación viral por reacción de cadena de polimerasa resultando VPH 16. A 20 meses de seguimiento, no hay evidencia clínica ni citológica de lesión recurrente. Es importante realizar la tipificación viral de estas lesiones por su relación con el carcinoma epidermoide de la vulva. Se realizó una revisión de la literatura. Abstract in english The vulvoperineal condylomatosis it’s a very frequent disease in reproductive age young women; it’s recommended to realize the viral typification, because the relation between some human papillomavirus subtypes with gynaecology epidermoid cancer. We present the case of a 39 years old female patient [...] who consulted to present a exofitic injury, warty that occupies the majora and minora labia of the vulva, clitoris, vaginal vestibule and perianal region; from which incisional biopsy was taken, reporting papilomatosis by human papillomavirus, without evidence of atypias. Patient went to operating room to receive a dermovulvectomy, whose definitive biopsy reported invasive epidermoid carcinoma well differentiated, focal, with free resection margins; it is completed with superficial and deep bilateral inguinal dissection without evidence of metastasic nodal involment. Viral tipificación by reaction of polymerase chain reaction was made being VPH 16. To 20 months of fall up, there are not clinical or cytological evidence of recurrent lesions. It is important to make the viral tipificación of these lesions by its relation with the epidermoid carcinoma of the vulva. A revision of literature was made.

  20. Testicular germinal tumors

    International Nuclear Information System (INIS)

    This work is about diagnosis, treatment and monitoring of testicular germinal tumors. The presumed diagnosis is based in the anamnesis, clinical examination, testicular ultrasound and tumor markers. The definitive diagnosis is obtained through the inguinal radical orchidectomy

  1. Giant Pelvic Retroperitoneal Epidermoid Cyst: A Rare Case Report

    OpenAIRE

    Fdili Alaoui, F. Z.; Oussaden, A.; H. Bouguern; El Fatemi, H.; Melhouf, M. A.; A. Amarti; Ait Taleb, K.

    2012-01-01

    Epidermoid cyst is a frequent benign cutaneous tumor. The pelvic localization does not occur very often. The literature that taps into such cases is very limited in scope. Here is a report of a 27-year-old woman with a giant pelvic retroperitoneal epidermoid cyst. The use of ultrasound exploration and computed tomography has indicated ovarian origins. The surgery also revealed a retroperitoneal epidermoid cyst, uterus and ovaries were all intact. The evacuation of a cyst was found to contain ...

  2. Cáncer de quiste en conducto tirogloso

    Directory of Open Access Journals (Sweden)

    Manuel Francisco Jiménez-Navarrete

    2013-12-01

    Full Text Available El quiste del conducto tirogloso es una de las anomalías del desarrollo que se presentan más frecuentemente en el cuello. La presencia en este de carcinoma aislado o concomitante con cáncer en tiroides, es muy infrecuente. Se expone aquí el caso de una paciente joven que se presentó con esta entidad. Se describe su presentación y manejo. Actualmente sigue su control en el Servicio de Endocrinología del Hospital San Vicente de Paúl, Heredia, Costa Rica.

  3. Epidermoid tumor in the sphenoid sinus--case report.

    Science.gov (United States)

    Ohta, S; Nishizawa, S; Ryu, H; Yokoyama, T; Hinokuma, K; Yamaguchi, M; Uemura, K

    1997-04-01

    A 36-year-old male presented with a very rare epidermoid tumor in the sphenoid sinus manifesting as paresis of the right sixth cranial nerve and diplopia. Computed tomography and magnetic resonance imaging revealed a mass lesion in the sphenoid sinus expanding to the clivus. The cystic tumor, which contained cholesterin crystals, was extensively removed via the transsphenoidal approach. Histological examination showed epidermoid cell layers, consistent with the diagnosis of epidermoid tumor. Epidermoid tumors should be considered in the differential diagnosis of lesions in the sphenoid sinus. PMID:9136562

  4. Orbital dermoid and epidermoid cysts: Case study

    Directory of Open Access Journals (Sweden)

    Veselinovi? Dragan

    2010-01-01

    Full Text Available Introduction. Dermoid and epidermoid cysts of the orbit belong to choristomas, tumours that originate from the aberrant primordial tissue. Clinically, they manifest as cystic movable formations mostly localized in the upper temporal quadrant of the orbit. They are described as both superficial and deep formations with most frequently slow intermittent growth. Apart from aesthetic effects, during their growth, dermoid and epidermoid cysts can cause disturbances in the eye motility, and in rare cases, also an optical nerve compression syndrome. Case Outline. In this paper, we described a child with a congenital orbital dermoid cyst localized in the upper-nasal quadrant that was showing signs of a gradual enlargement and progression. The computerized tomography revealed a cyst of 1.5-2.0 cm in size. At the Maxillofacial Surgery Hospital in Niš, the dermoid cyst was extirpated in toto after orbitotomy performed by superciliary approach. Postoperative course was uneventful, without inflammation signs, and after two weeks excellent functional and aesthetic effects were achieved. Conclusion. Before the decision to treat the dermoid and epidermoid cysts operatively, a detailed diagnostic procedure was necessary to be done in order to locate the cyst precisely and determine its size and possible propagation into the surrounding periorbital structures. Apart from cosmetic indications, operative procedures are recommended in the case of cysts with constant progressions, which cause the pressure to the eye lobe, lead to motility disturbances and indirectly compress the optical nerve and branches of the cranial nerves III, IV and VI.

  5. Radiation Therapy for Testicular Cancer

    Science.gov (United States)

    ... chemo and stem cell transplant for testicular cancer Radiation therapy for testicular cancer Radiation therapy uses high-energy rays or particles to ... cells or slow their growth. In testicular cancer, radiation is mainly used to kill cancer cells that ...

  6. Quistes pulmonares congénitos / Congenital lung cysts

    Scientific Electronic Library Online (English)

    Nuvia, Suárez García; Sergio Germán, Piloña Ruiz; Omar León, Vara Cuesta; Rita Inés, Milians Casanova; Mirka, Rosa Torres.

    2014-06-01

    Full Text Available Introducción: las malformaciones pulmonares congénitas constituyen una alteración en el desarrollo embriológico y fetal de las distintas estructuras pulmonares y una rara expresión de estas son los quistes pulmonares congénitos. Caso clínico: se presenta un recién nacido a término, de buen peso, asi [...] ntomático y estable hasta el tercer día de vida al debutar con un estado de shock séptico secundario, de bronconeumonía complicada con derrame pleural derecho. En los estudios evolutivos hacia el cuarto de día de vida se le diagnostica como hallazgo radiológico la presencia de quistes pulmonares que evolucionan de forma asintomática. Después de una valoración multidisciplinaria es egresado con un seguimiento por su condición de alto riesgo. Actualmente saludable y con buen desarrollo psicomotor. Conclusiones: la importancia del tema que se presenta es que se describe una presentación rara de quistes pulmonares congénitos en un recién nacido que desarrolló un estadio avanzado de sepsis. Abstract in english Introduction: congenital lung malformations constitute an alteration in the embryonic and fetal development of the different lung structures and a rare expression of these congenital lung cysts. Case report: termed newborn, good weight, evolving asymptomatic and stable until the third day of life to [...] debut a state of septic shock secondary to complicated bronchopneumonia with right pleural effusion. In evolutionary studies by the fourth day of life it is diagnosed, as radiological finding, the presence of lung cysts evolving asymptomatically. After a multidisciplinary assessment there is a graduate tracking of their status, with high risk. Currently healthy and good psychomotor development. Conclusions: the importance of the issue presented is a rare presentation of congenital lung cysts in a newborn who developed an advanced stage of sepsis described.

  7. Presentación inusual de los quistes aracnoideos

    Scientific Electronic Library Online (English)

    Fidel, Sosa; Facundo, Rodríguez; Fernando, Palma; Graciela, Zuccaro.

    2006-09-01

    Full Text Available Objetivo. Describir y analizar la asociación entre quistes aracnoideos e higroma subdural. Esta es considerada una complicación excepcional, con sólo 24 casos reportados en la literatura, siendo de cinco casos la serie publicada más numerosa. Método. Se realizó el análisis retrospectivo de las histo [...] rias clínicas de 5 pacientes portadores de quiste aracnoideo, en los que la forma de presentación consistió en higroma subdural e hipertensión endocraneana. Resultados. El rango de edad fue entre 3 y 15 años (promedio: 7 años). La relación M/F fue 3/2. En 3 casos los síntomas se presentaron después de un traumatismo encefalocraneal leve y en los 2 restantes fue espontáneo. Todos se manifestaron con síntomas de hipertensión endocraneana y edema de papila bilateral, en 2 de ellos se constató paresia del VI par izquierdo. A todos se les realizó TAC y en 2 casos IRM. En los 5 pacientes se constató un higroma subdural con efecto de masa y quiste aracnoideo de fosa media. Se realizó tratamiento quirúrgico de urgencia en los 5 casos. Todos los pacientes evolucionaron favorablemente con desaparición del higroma subdural. Actualmente se encuentran asintomáticos con un examen neurológico y fondo de ojo normal. Conclusión. Si bien el higroma subdural con hipertensión endocraneana es una complicación poco usual, debe ser tenida en cuenta como una de las formas de presentación clínica de los quistes aracnoideos, la cual requiere inmediata resolución quirúrgica. Abstract in english Objetive: To analyze and describe the association between arachnoid cysts and subdural hygroma. This association is an unusual complication of which only 24 cases have been reported in the literature. Methods: The clinical records of 5 patients with arachnoid cysts presenting as a subdural hygroma w [...] ith increased intracranial pressure were analyzed retrospectively. Results: The ages of the patients ranged between 3 and 15 years (mean: 7 years). M/F ratio was 3/2. Onset of symptoms was postraumatic in 3 and spontaneous in 2. All patients presented symptoms of increased intracranial pressure and bilateral papilledema, and in 2 out of 5 paresis of the VI cranial nerve was found. All children underwent CAT scan and MRI was performedin 2. In all patients, subdural hygroma with mass effect and arachnoid cyst of the middle fossa was found. Emergency surgery was carried out in all cases. All patients evolved favorably with complete disappearance of the subdural hygroma. They are currently asymptomatic with normal neurological examination and fundoscopy. Conclusion: Even though subdural hygroma with increased intracranial pressure is an unusual complication, it should be known as one of the clinical presentations of arachnoid cysts, which required immediate surgical intervention.

  8. Isodense epidermoid cyst in the pineal region

    International Nuclear Information System (INIS)

    A 69-year-old male was admitted complaining of gait disturbances and diplopia, 2.5 years after an episode of serous meningitis. Neurological examination on admission disclosed Parinaud's sign, unsteady gait and dysdiadochokinesis on the left side. A striking finding on the computerized tomography (CT) was the left to right shift of the posterior portion of the third ventricle without visualization of the quadrigeminal and ambient cisterns, which were almost completely occupied by an isodense mass accompanied by high dense flecks and a low dense part. Enhanced CT showed positive enhancement in the vicinity of the pineal calcification. By the suboccipital supracerebellar approach, an encapsulated mass containing brownish yellow fluid was subtotally removed and a histological examination of it revealed epidermoid tissue and hemosiderin deposits in the solid portion. Few reports of isodense epidermoid cysts have so far been found in the literature giving a full explanation for this unusual CT attenuation value. Based on the clinical course and histology of this case, the pathogenesis of the unusual density is discussed along the following lines: The mixture of the low dense factor due to cholesterin and the high dense factor due to prior bleeding is believed to result in the isodense attenuation value in the liquid portion. Also, in the solid part, a microscopically mixed texture of deposited hemosiderin and cholesterin clefts in the inflammatory granulomatous tissue could explain its density on the CT scan. (author)

  9. CT scan findings of malignant epidermoid cyst

    International Nuclear Information System (INIS)

    The authors report a case of malignant epidermoid cyst (MEC) and discuss the characteristic findings on computed tomography (CT) scan, the differential diagnosis and the difference from the atypical findings of benign epidermoid cyst (BEC) with a review of the literature. A 60-year-old female complained of right oculomotor palsy and syncopal attacks. Plain CT scan revealed an irregularly low-density lesion with a ring-like and nodular high-density area mainly in the suprasellar cistern and midbrain, and another iso- to a slightly high-density area in the medial aspect of the right temporal lobe. On enhanced CT scan, a faint and inhomogeneous enhancement was observed in the lesion of the right temporal lobe. Surgical treatment was performed, and pathological examination of the specimen from the medial aspect of the right temporal lobe showed malignant change in the BEC. As a common and characteristic feature of CT scan findings of the present and the five previously reported cases, MEC shows homogeneous or inhomogeneous enhancement in the iso- to a slightly high-density lesion or the low-density lesion found in a typical BEC. (author)

  10. QUISTE LEPTOMENINGEO: HALLAZGOS EN TC Y RM

    Directory of Open Access Journals (Sweden)

    Francisco Javier de Castro G

    2004-01-01

    Full Text Available El quiste leptomeníngeo es una complicación de las fracturas craneales que ocurre mayoritariamente en población pediátrica. La existencia del mismo en adultos es rara. Presentamos el caso de un varón de 47 años que mostró un cuadro de acorchamiento en miembro superior derecho y desviación de la comisura bucal del que se recuperó en una hora. Los estudios de neuroimagen mostraron una destrucción irregular del hueso temporal derecho y una hipodensidad del tejido cerebral subyacente. La cirugía y el estudio histológico del hueso resecado mostraron que se trataba de un quiste leptomeníngeo asociado a un infarto cerebralTraumatic leptomeningeal cyst as a complication of skull fractures was initially thought to occur primarily in the pediatric population. The occurrence of a traumatic leptomeningeal cyst in the adult population is rare. We report the case of a 47 year old male. He presented complaining of loss of sensation in the right arm and desviation of the mouth, from which he recovered within an hour. Neuro-imaging studies showed irregular destruction of the right temporal bone and hypodensity of the underlying brian tissue. Surgical operation and histological study of the bone removed showed that it was a leptomeningeal cyst, associated with a cerebral infarct

  11. QUISTE LEPTOMENINGEO: HALLAZGOS EN TC Y RM

    Scientific Electronic Library Online (English)

    Francisco Javier, de Castro G; José Francisco, Asensio C; María Teresa, Adeva B; Paloma, García I.

    Full Text Available El quiste leptomeníngeo es una complicación de las fracturas craneales que ocurre mayoritariamente en población pediátrica. La existencia del mismo en adultos es rara. Presentamos el caso de un varón de 47 años que mostró un cuadro de acorchamiento en miembro superior derecho y desviación de la comi [...] sura bucal del que se recuperó en una hora. Los estudios de neuroimagen mostraron una destrucción irregular del hueso temporal derecho y una hipodensidad del tejido cerebral subyacente. La cirugía y el estudio histológico del hueso resecado mostraron que se trataba de un quiste leptomeníngeo asociado a un infarto cerebral Abstract in english Traumatic leptomeningeal cyst as a complication of skull fractures was initially thought to occur primarily in the pediatric population. The occurrence of a traumatic leptomeningeal cyst in the adult population is rare. We report the case of a 47 year old male. He presented complaining of loss of se [...] nsation in the right arm and desviation of the mouth, from which he recovered within an hour. Neuro-imaging studies showed irregular destruction of the right temporal bone and hypodensity of the underlying brian tissue. Surgical operation and histological study of the bone removed showed that it was a leptomeningeal cyst, associated with a cerebral infarct

  12. Pineal epidermoid cyst: case report and review of the literature

    OpenAIRE

    Hassani, Fahd Derkaoui; Bouchaouch, Abdelali; El Fatemi, Nizare; Gana, Rachid; El Abbadi, Najia; Maaqili, Moulay Rachid

    2014-01-01

    Intracranial epidermoid cysts are one of the rare tumors of all intracranial tumors. They represent 0,2 to 1% of intracranial tumors and 7% of tumors in the cerebellopontine angle. The pineal region is exceptionally subject to such kind of tumor. Cushing was the first to report the pineal localization of the epidermoid cyst in 1928. Up to now, 85 cases of pineal epidermoid cyst were cited in the literature. We report a clinical case concerning a 45 years old man who presented an intracranial ...

  13. Estudio inmunohistoquímico del carcinoma epidermoide de labio / Epidermoid carcinoma of the lip: An immunohistochemical study

    Scientific Electronic Library Online (English)

    Belén, García-Montesinos Perea; José Fernando, Val Bernal; Ramón, Saiz Bustillo.

    2005-12-01

    Full Text Available Objetivos: Determinar la sobreexpresión de las proteínas c-erb-B2, p53, bcl-2, Ki67 y CD44varV6 y establecer su valor pronóstico en el carcinoma epidermoide de labio. Diseño del estudio: Estudio inmunohistoquímico de las proteínas p53, c-erb-B2, bcl-2, ki67 y CD44varV6 en 79 carcinomas epidermoides [...] de labio diagnosticados y tratados a lo largo de un periodo de 20 años. Los datos obtenidos fueron sometidos a análisis estadístico uni y multivariante. Resultados: La inmunotinción fue positiva en el 75% de los casos para la proteína c-erb-B2, en el 70,6% para la proteína p 53, en el 3,8% para la proteína bcl-2 y en el 89,9% para la molécula de adhesión cd44varV6. La expresión proteica de ki67 osciló entre un mínimo de 0% y un máximo de 6,29%. Los factores inmunohistoquímicos analizados no presentaron valor pronóstico en el carcinoma epidermoide de labio, y solamente los pacientes afectados por este tipo de tumores que expresaban la molécula de adhesión CD44varV6 se asociaron de forma significativa con una mayor supervivencia mediante el análisis de Kaplan-Meier. Conclusiones: Las técnicas inmunohistoquímicas analizadas para el estudio anatomopatológico del carcinoma epidermoide de labio no deberían realizarse rutinariamente, dado su mayor coste y su menor utilidad en la práctica clínica diaria. Abstract in english Objectives: To determine the expression of the c-erb-B2, p53, bcl-2, Ki67 and CD44varV6 proteins, and to establish their prognostic value in epidermoid carcinoma of the lip. Study design: Immunohistochemical study of the c-erb-B2, p53, bcl-2, Ki67 and CD44varV6 proteins in 79 epidermoid carcinomas o [...] f the lip, diagnosed and treated over a period of 20 years. The data obtained were subjected to uni- and multi-variate statistical analyses. Results: Immunostaining was positive in 75% of cases for c-erb-B2 protein, in 70.6% for p53 protein, in 3.8% for bcl-2 protein and in 89.9% for adhesion molecule CD44varV6. Ki67 protein expression varied between a minimum of 0% and a maximum of 6.29%. Most immunohistochemical factors analyzed presented no prognostic value for epidermoid carcinoma of the lip. Only those patients affected by this type of tumor that expressed the adhesion molecule CD44varV6 were significantly associated with a greater survival calculated by means of Kaplan-Meier analysis. Conclusions: The immunohistochemical techniques analyzed for the anatomicopathological study of epidermoid carcinoma of the lip should not routinely be used due to their high cost and low utility in daily clinical practice.

  14. Testicular Cancer Screening

    Science.gov (United States)

    ... condition called cryptorchidism (an undescended testicle) is a risk factor for testicular cancer. Anything that increases the chance of getting a ... if you think you may be at risk. Risk factors for testicular cancer include the following: Having cryptorchidism (an undescended testicle). ...

  15. Pineal epidermoid cyst: case report and review of the literature

    Science.gov (United States)

    Hassani, Fahd Derkaoui; Bouchaouch, Abdelali; El Fatemi, Nizare; Gana, Rachid; El Abbadi, Najia; Maaqili, Moulay Rachid

    2014-01-01

    Intracranial epidermoid cysts are one of the rare tumors of all intracranial tumors. They represent 0,2 to 1% of intracranial tumors and 7% of tumors in the cerebellopontine angle. The pineal region is exceptionally subject to such kind of tumor. Cushing was the first to report the pineal localization of the epidermoid cyst in 1928. Up to now, 85 cases of pineal epidermoid cyst were cited in the literature. We report a clinical case concerning a 45 years old man who presented an intracranial hypertension during 18 months. The clinical examination found a hemiparesis with a facial hypoesthesis. The MRI showed a process of the pineal region. The patient underwent a surgery with a large resection. The histological examination confirms the epidermoid cyst. Many approaches were described in the literature. The outcome is related to this localization. PMID:25489364

  16. Concomitant occurrence of vestibular schwannoma and epidermoid tumor

    Directory of Open Access Journals (Sweden)

    B V Savitr Sastri

    2013-01-01

    Full Text Available The occurrence of two tumors adjacent to each other at the same site is very rare. We present here, a patient with a vestibular schwannoma found adjacent to an epidermoid tumor in the cerebellopontine angle.

  17. Quiste óseo aneurismático simulando tumoración de rinofaringe

    Scientific Electronic Library Online (English)

    Alirio, Mijares B; Carmen M, Suárez; Nelson, Urdaneta L; Leonardo, Badell; Salvador, Somaza; Dilmeri, Castro.

    2011-06-01

    Full Text Available Los quistes óseos aneurismáticos del área de cabeza y cuello representan menos del 5 % de todos los tumores óseos. Son lesiones benignas, que comúnmente afectan las metáfisis de los huesos largos y las vértebras como en el caso que se describe a continuación, simulando una lesión de la rinofaringe. [...] Se describe su manejo y tratamiento. Abstract in english The aneurismal of bone cyst of the head and neck localization, represent less than the 5 % of the all bone tumors. They are benign lesions, and commonly affecting the metaphysis of the long bones and vertebrae, like in the case we described below, it simulating the rhino pharynx lesion. We describe [...] the management and treatment.

  18. Epidermoid cyst of the posterior fossa: a case report Cisto epidermoide da fossa posterior: relato de caso

    Directory of Open Access Journals (Sweden)

    Eduardo Cambruzzi

    2011-02-01

    Full Text Available Epidermoid cysts of the central nervous system are uncommon conditions, which are frequently located in the cerebellopontine angle and around the pons. They are covered with keratinized squamous epithelium and keratin lamella, which give its contents a soft, white-pearly appearance. Epidermoid cysts are mostly originated from malformations, presumably associated with surface elements of the nervous system ectoderm during the closure of the neural groove or formation of secondary cerebral vesicles. The authors describe a case of epidermoid cyst in the posterior fossa causing hydrocephalus and review morphologic and diagnostic criteria of this lesion.Os cistos epidermoides do sistema nervoso central (SNC são condições incomuns, estando localizados mais frequentemente no ângulo pontocerebelar e ao redor da ponte. Eles são revestidos por epitélio escamoso queratinizado e lamelas de queratina, tornando seu conteúdo branco-perolado e pastoso. Os cistos epidermoides são, na maioria das vezes, originados de malformações, possivelmente associados ao entremeio de elementos superficiais do ectoderma do SNC durante o fechamento da placa neural, ou formação das vesículas cerebrais secundárias. Os autores descrevem um caso de cisto epidermoide da fossa posterior determinando hidrocefalia e revisam critérios morfológicos e diagnósticos dessa lesão.

  19. Epidermoid cyst of the posterior fossa: a case report / Cisto epidermoide da fossa posterior: relato de caso

    Scientific Electronic Library Online (English)

    Eduardo, Cambruzzi; Karinelli, Presa; Luciano Carvalho, Silveira; Gerson Evandro, Perondi.

    2011-02-01

    Full Text Available Os cistos epidermoides do sistema nervoso central (SNC) são condições incomuns, estando localizados mais frequentemente no ângulo pontocerebelar e ao redor da ponte. Eles são revestidos por epitélio escamoso queratinizado e lamelas de queratina, tornando seu conteúdo branco-perolado e pastoso. Os ci [...] stos epidermoides são, na maioria das vezes, originados de malformações, possivelmente associados ao entremeio de elementos superficiais do ectoderma do SNC durante o fechamento da placa neural, ou formação das vesículas cerebrais secundárias. Os autores descrevem um caso de cisto epidermoide da fossa posterior determinando hidrocefalia e revisam critérios morfológicos e diagnósticos dessa lesão. Abstract in english Epidermoid cysts of the central nervous system are uncommon conditions, which are frequently located in the cerebellopontine angle and around the pons. They are covered with keratinized squamous epithelium and keratin lamella, which give its contents a soft, white-pearly appearance. Epidermoid cysts [...] are mostly originated from malformations, presumably associated with surface elements of the nervous system ectoderm during the closure of the neural groove or formation of secondary cerebral vesicles. The authors describe a case of epidermoid cyst in the posterior fossa causing hydrocephalus and review morphologic and diagnostic criteria of this lesion.

  20. Surgery for Testicular Cancer

    Science.gov (United States)

    ... from the tumor into the bloodstream. All testicular cancers are typically treated with this surgery, even those that have spread. Retroperitoneal lymph node dissection (RPLND) Depending on the type ...

  1. Epidermóide intra-raqueano / Intraspinal epidermoid

    Scientific Electronic Library Online (English)

    Antonio B., Lefèvre; Rolando A., Tenuto; Amelia T. M., Vasconcelos.

    1957-03-01

    Full Text Available Caso de tumor epidermóides intra-raqueano, extra-medular ao nível de T12, diagnosticado e tratado cirùrgicamente, em um menino de 9 anos. Os autores chamam a atenção para a dificuldade diagnostica deste caso, cujo quadro clínico lembrava o de uma radiculopatia compressiva por hérnia de disco interve [...] rtebral. A evolução foi favorável, com recuperação total, sem seqüelas. Lembram os autores a necessidade de ser precizada a designação dêsses tumores, que são muitas vêzes confundidos com os cistos dermóides e outros tumores congênitos. Abstract in english Case report of an intradural, extramedullary epidermoid tumor, at the level of T12, in a 9 year old boy, treated surgically. The authors stress the difficulty to diagnose this case, for the clinical picture seemed that of a radiculopaty due to compression by an intervertebral herniated disc. The evo [...] - lution was favorable, with complete recuperation and without sequelae. The authors point out the necessity of defining the designation of these tumors, often confused with dermoid cysts and other congenital tumors.

  2. Epidermoid cyst of the ovay in young woman: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Jung Hee; Kim, See Hyung; Kang, Yu Na; Kim, Mi Jeong [Keimyung University School of Medicine, Dongsan Medical Center, Daegu (Korea, Republic of)

    2015-06-15

    In general, ovarian epidermoid cysts coexist with surface epithelial ovarian tumors. Pure epidermoid cysts are extremely rare diseases, comprising less than 1% of surface ovarian tumors. We present here a pathologically proven epidermoid cyst of the ovary in a young woman with ultrasonographic and magnetic resonance findings.

  3. Epidermoid cyst of the ovay in young woman: A case report

    International Nuclear Information System (INIS)

    In general, ovarian epidermoid cysts coexist with surface epithelial ovarian tumors. Pure epidermoid cysts are extremely rare diseases, comprising less than 1% of surface ovarian tumors. We present here a pathologically proven epidermoid cyst of the ovary in a young woman with ultrasonographic and magnetic resonance findings

  4. Varicocele and testicular function

    Directory of Open Access Journals (Sweden)

    Alexander W Pastuszak

    2015-01-01

    Full Text Available Testicular varicocele, a dilation of the veins of the pampiniform plexus thought to increase testicular temperature via venous congestion, is commonly associated with male infertility. Significant study has clarified the negative impact of varicocele on semen parameters and more recent work has shed light on its detrimental effects on the molecular and ultrastructural features of sperm and the testicular microenvironment, as well as more clearly defined the positive impacts of treatment on couples? fertility. The relationship between varicocele and testicular endocrine function, while known for some time based on histologic evaluation, has become more apparent in the clinical setting with a growing link between varicocele and hypogonadism. Finally, in the pediatric setting, while future study will clarify the impact of varicocele on fertility and testicular function, recent work supports a parallel effect of varicocele in adolescents and adults, suggesting a re-evaluation of current treatment approaches in light of the progressive nature of the condition and potential increased risk of future disease.

  5. Giant Vulvar Epidermoid Cyst in an Adolescent Girl

    OpenAIRE

    Karaman, Erbil; Çim, Numan; Akdemir, Zülküf; Elçi, Erkan; Akdeniz, Hüseyin

    2015-01-01

    Introduction. Vulvar cyst in adolescent girls is very uncommon. Epidermoid cyst can be seen in many sites including face, trunk, and extremities but its occurrence in vulva is uncommon. This is the first case of epidermoid cyst of vulva reported in an adolescent girl. Case. A 17-year-old, adolescent girl admitted to our gynecology outpatient clinic with a complaint of painful and palpable mass in her vulva. On examination, a giant mass located in left vulva and labia majora with 11?cm in diam...

  6. QUISTES NO NEOPLÁSICOS Y NEOPLÁSICOS DE OVARIO EN EDAD PEDIÁTRICA

    Directory of Open Access Journals (Sweden)

    José Raúl Sánchez Aguilar

    2006-01-01

    Full Text Available En Cuba los tumores y quistes de ovario en la infancia ocupan aproximadamente el 1% de todos los procesos tumorales, durante esta etapa de la vida, más del 50 % de estos tumores corresponden como quistes simples, teratomas benignos, y quistes foliculares, por lo que se realizó un estudio retrospectivo longitudinal en niños con incidencias de estos tumores en el Hospital Pediátrico ¿Eduardo Agramonte Piña¿, Camagüey, desde julio de 1973 a julio de 2004, con el objetivo de valorar la incidencia de estos tumores en niños. El universo y muestra lo constituyeron los 170 pacientes ingresados por dicha enfermedad. Se revisaron las historias clínicas de los enfermos. Se confeccionó un formulario que incluyó variables como. la edad, la forma de presentación, el lado más afecto, el histología, los complementarios realizados y las complicaciones, donde predominó el rango de edad entre los 11y15 años con 122 pacientes para un 71.8 %. Existió un aumento de la incidencia en el ovario derecho para un 71.8 %. Las lesiones de mayor prevalencia fueron los tumores quísticos benignos (teratomas quísticos con 107 de los pacientes, seguido de los quistes no neoplásicos (foliculares para un 12.4 %.El Rx simple de abdomen y el USG abdominal fueron los complementarios de mayor utilidad.

  7. Quiste óseo aneurismático de la rótula: Presentación de un caso

    Scientific Electronic Library Online (English)

    GASTON, ARANGO GARCIA; EDDY, SANCHEZ NODA; RODRIGO, ALVAREZ LORENZO; RICARDO, TARRAGONA REINOSO.

    1995-12-01

    Full Text Available Se presenta un paciente con un quiste óseo aneurismático en la rótula, lo que constituye una localización muy atípica. Se expone la sintomatología clínica, así como la novedosa combinación de la biopsia ósea y la artroscopia para evaluar mejor la articulación y el tratamiento practicado, que consist [...] ió en la patelectomía con la técnica de Boyd.

  8. Epidermoid cyst of the ileum in a miniature dachshund dog.

    Science.gov (United States)

    Shimamura, Shunsuke; Kainuma, Risa; Kimura, Ken; Okamura, Yasuhiko; Kobayashi, Saori; Katayama, Masaaki; Sato, Reeko; Yasuda, Jun

    2014-04-01

    A 13-year-old castrated male miniature dachshund dog was presented with chronic vomiting and diarrhea. Contrast radiography and surgical exploration revealed an ileal cyst, which was excised. A diagnosis of epidermoid cyst was made from a combination of the clinical findings and histological examination of the surgical specimen. PMID:24688137

  9. Epidermoid cyst of the ileum in a miniature dachshund dog

    OpenAIRE

    Shimamura, Shunsuke; Kainuma, Risa; KIMURA, Ken; OKAMURA, Yasuhiko; KOBAYASHI, Saori; KATAYAMA, Masaaki; Sato, Reeko; Yasuda, Jun

    2014-01-01

    A 13-year-old castrated male miniature dachshund dog was presented with chronic vomiting and diarrhea. Contrast radiography and surgical exploration revealed an ileal cyst, which was excised. A diagnosis of epidermoid cyst was made from a combination of the clinical findings and histological examination of the surgical specimen.

  10. Epidermoid carcinomas of the conjunctive with intraorbital and intraocular invasion

    International Nuclear Information System (INIS)

    The epidermoid carcinomas of the conjunctive are tumors in general of low incidence with a range between 0.13 and 1.9 cases for 100,000 inhabitants; this incidence is superior however in tropical countries. The incidences reported for intra orbital and intraocular invasive forms have a range between 2 and 12% which demonstrates the aggressive character of this tumor. The handling of epidermoid carcinoma of the conjunctive in initial stages is very conservative, but in their natural history this tumor can invade the ocular globe, orbit, neighboring regions and distant organs, thereby of importance an early diagnosis and an appropriate treatment. Our objective was to know the incidence of epidermoid carcinoma of the conjunctiva with intraocular and intra orbital invasion in the Havana National Oncology Institute. We carry out a retrospective and descriptive study of 18 patients with clinical diagnoses and histology of epidermoid carcinoma of the conjunctiva with orbit infiltration assisted from January of 1995 until December 2003 classified as T4 NO MO. The evaluated parameters were: age, sex, initial treatment and evolution. Middle aged of our serie it was 58.7 years, excisional surgery and deep radiotherapy was the initial treatment applied in 83.33% of the cases. In its evolution eight cases (44.44%) of the patients had unfavorable result and radical surgery was carried out in 50% of the patients. (The author)

  11. Quistes renales: concepto y clasificación / Renal cysts: concept and classification

    Scientific Electronic Library Online (English)

    Sandalio, Durán Álvarez.

    2007-03-01

    Full Text Available Con la finalidad de poder ayudar a los estudiantes de medicina y médicos generales básicos, se hace una breve revisión sobre los quistes renales, tanto de los que constituyen una enfermedad por sí mismos como de los que pueden estar asociados a diferentes síndromes y los que pueden aparecer evolutiv [...] amente en el curso de una enfermedad renal. Conocer las causas principales que producen quistes renales es esencial para el correcto asesoramiento genético. Consideramos que esta clasificación, aunque no perfecta ni completa, puede ser útil en la práctica médica. En ella se trata de agrupar en primer lugar a las enfermedades con herencia dominante o recesiva, y además a los quistes asociados a síndromes malformativos, las alteraciones cromosómicas que pueden tener quistes renales y los quistes no genéticos que pueden ser congénitos o adquiridos. Abstract in english To help medical students and basic general physicians, a brief review is made on renal cysts, including those that are a disease by themselves, the associated with different syndromes, and the ones that may appear evolutively in the course of a renal disease. Knowing the main causes of renal cysts i [...] s essential for an appropriate genetic counselling. We consider that this classification, although it is neither perfect nor complete, may be useful in medical practice. An effort is made to group in it , in the first place, the diseases with dominant or recessive inheritance, the cysts associated with malformation syndromes, the chromosomal disorders that may have renal cysts, and the nongenetic cysts that may be congenital or acquired.

  12. Quiste óseo aneurismático Aneurysmal bone cyst

    Directory of Open Access Journals (Sweden)

    Ferdinando de Conto

    2012-06-01

    Full Text Available El quiste óseo aneurismático (QOA es una lesión benigna rara en huesos maxilares, su mayor frecuencia es en huesos largos del esqueleto y columna vertebral. Algunos autores especulan que el origen sea por trauma, mala formación o un neoplasma. El aspecto radiográfico puede mostrar desde una imagen difusa hasta una imagen bien definida, muy semejante a las otras lesiones de los maxilares volviendo el diagnóstico diferencial amplio. Con la destrucción del córtex óseo puede todavía formar una imagen reaccional del periostio en forma de rayos de sol, característico de una lesión maligna. En este estudio, se presenta caso de paciente femenino, 17 años de edad, que buscó el Servicio de Cirugía y Traumatología Buco maxilofacial del Hospital São Vicente de Paulo-RS, que presentó dolor y aumento de volumen en la mandíbula. Informó que hace cerca de un año empezó a sentir malestar en la región junto al ángulo mandibular derecho, lo cual fue progresivamente aumentando de volumen. El aspecto radiográfico acordaba una lesión maligna. Después de la confirmación histopatológica de QOA, el tratamiento seleccionado para el caso fue quirúrgico conservador, con legrado de la cavidad ósea, y fue mantenido en control posoperatorio de rutina con 6 y 18 meses. En las radiografías panorámicas realizadas se verifica la neoformación ósea y cura del caso.The aneurysmal bone cyst (ABC is a benign and rare lesion in maxillary bones, is more frequent in largo bones of skeletal and spinal column. Some authors speculate about that its origin be traumatic, malformation of neoplasm. The radiographic appearance may to show from a diffuse image up to a well defined image very similar to the other maxillary lesions turning wide the differential diagnosis. With destruction of the bon cortex it is possible to create a reaction image of periosteum in sunbeams characteristic of malignant lesion. This is the case of a female patient aged 17 seeking help in the Bucco-maxillofacial Surgery and Traumatology Service of the São Vicente de Paulo Hospital _ RS, presenting with pain and an increased mandibular volume. She manifested that around one year she began to feel a discomfort next to he right mandibular angle, which was progressively increasing the volume. The radiographic appearance resembled a malignant lesion. After the histopathology verification of ABC, treatment choosed for this case was of type conservative surgical with bone cavity curettage and was maintained under systemic postoperative control for 6 and 18 months. In the taken panoramic radiographies is verified the bone neoformation and the cure of case.

  13. Quiste óseo aneurismático / Aneurysmal bone cyst

    Scientific Electronic Library Online (English)

    Ferdinando, de Conto; Manoela, Moura de Bortoli; Jéssica, Galvan; Gisele, Rovani; Mateus, Ericson Flores; Roque Miguel, Rhoden.

    2012-06-01

    Full Text Available El quiste óseo aneurismático (QOA) es una lesión benigna rara en huesos maxilares, su mayor frecuencia es en huesos largos del esqueleto y columna vertebral. Algunos autores especulan que el origen sea por trauma, mala formación o un neoplasma. El aspecto radiográfico puede mostrar desde una imagen [...] difusa hasta una imagen bien definida, muy semejante a las otras lesiones de los maxilares volviendo el diagnóstico diferencial amplio. Con la destrucción del córtex óseo puede todavía formar una imagen reaccional del periostio en forma de rayos de sol, característico de una lesión maligna. En este estudio, se presenta caso de paciente femenino, 17 años de edad, que buscó el Servicio de Cirugía y Traumatología Buco maxilofacial del Hospital São Vicente de Paulo-RS, que presentó dolor y aumento de volumen en la mandíbula. Informó que hace cerca de un año empezó a sentir malestar en la región junto al ángulo mandibular derecho, lo cual fue progresivamente aumentando de volumen. El aspecto radiográfico acordaba una lesión maligna. Después de la confirmación histopatológica de QOA, el tratamiento seleccionado para el caso fue quirúrgico conservador, con legrado de la cavidad ósea, y fue mantenido en control posoperatorio de rutina con 6 y 18 meses. En las radiografías panorámicas realizadas se verifica la neoformación ósea y cura del caso. Abstract in english The aneurysmal bone cyst (ABC) is a benign and rare lesion in maxillary bones, is more frequent in largo bones of skeletal and spinal column. Some authors speculate about that its origin be traumatic, malformation of neoplasm. The radiographic appearance may to show from a diffuse image up to a well [...] defined image very similar to the other maxillary lesions turning wide the differential diagnosis. With destruction of the bon cortex it is possible to create a reaction image of periosteum in sunbeams characteristic of malignant lesion. This is the case of a female patient aged 17 seeking help in the Bucco-maxillofacial Surgery and Traumatology Service of the São Vicente de Paulo Hospital _ RS, presenting with pain and an increased mandibular volume. She manifested that around one year she began to feel a discomfort next to he right mandibular angle, which was progressively increasing the volume. The radiographic appearance resembled a malignant lesion. After the histopathology verification of ABC, treatment choosed for this case was of type conservative surgical with bone cavity curettage and was maintained under systemic postoperative control for 6 and 18 months. In the taken panoramic radiographies is verified the bone neoformation and the cure of case.

  14. Testicular cancer and antecedent diseases.

    OpenAIRE

    Swerdlow, A.J.; Huttly, S R; Smith, P. G.

    1987-01-01

    A case-control study of the aetiology of testicular cancer was conducted using information obtained by interview and from case-notes of 259 cases with testicular cancer and two sets of control patients -238 men with diagnoses other than testicular cancer attending the same radiotherapy centres as those attended by the cases, and 251 hospital in-patients not attending radiotherapy departments. Logistic regression analyses were performed, after stratifying by age and region of residence, to est...

  15. Toxoplasmosis testicular: un caso raro de masa testicular / Testicular toxoplasmosis: a rare case of mass testicular

    Scientific Electronic Library Online (English)

    F., Barreto; F., Hering; M.F., Dall’Oglio; D., Martini Filho; J.C., Campagnari; M., Srougi.

    2008-06-01

    Full Text Available El Toxoplasma gondii es un protozoario intracelular que infecta aves y mamíferos. La infección aguda es asintomática en pacientes inmunocompetentes. En pacientes con deficiencia inmunológica (síndrome de la inmunodeficiencia adquirida, linfomas o pacientes sometidos a terapia con corticoides para pr [...] evención de rechazo de transplante de órganos) la infección puede ser fatal. Nosotros describimos un caso poco común de toxoplasmosis testicular en paciente sometido a transplante renal hace 6 años con serología negativa para el virus VIH y sin toxoplasmosis sistémica. Abstract in english Toxoplasma gondii is an intracellular protozoan infecting birds and mammals. Acute infection is asymptomatic in immune competent people. For immune deficient patients (acquired immune deficiency syndrome, lymphoma patients or those under steroids to prevent organ transplantation rejection) infection [...] may be lethal. We describe an uncommon case of testicular toxoplasmosis in patient under steroids after organ transplantation with no positive serum test for HIV and/or systemic toxoplasmosis.

  16. En las enfermedades intersticiales difusas,¿todos los quistes son realmente quistes? Diffuse interstitial diseases: are all cysts real cysts?

    Directory of Open Access Journals (Sweden)

    Juan Carlos Spina

    2010-04-01

    Full Text Available Propósito: Demostrar que los cortes axiales de tomografía computada de alta resolución (TCAR son insuficientes para una correcta evaluación de las enfermedades pulmonares intersticiales difusas y que adicionar Proyección de Mínima Intensidad (MinIP aumenta la especificidad del diagnóstico. Material y Métodos: Estudios previos donde se observaban quistes pequeños subpleurales se seleccionaron 39 TCAR de 33 pacientes con colagenopatías confirmadas y 6 con enfermedad intersticial idiopática y se los reexaminó entre octubre de 2008 y junio de 2009. El equipo utilizado fue un tomógrafo computado multislice Philips Brillance de 16 canales. Los cortes fueron de 1 mm de espesor, de ápices a bases. La evaluación se realizó con la técnica habitual, adicionando la MinIP en cortes axiales, sagitales y coronales, con rotación del parénquima y especial atención en las áreas que presentaban quistes. Se efectuaron además cortes en espiración. Resultados: De 20 TCAR que mostraban quistes subpleurales con la técnica habitual, 14 (70% correspondieron a bronquioloectasias. En 12 casos, todas las imágenes eran bronquioloectasias; en 2 casos, ellas predominaban, observándose también quistes aislados. Se pudo definir la existencia de quistes verdaderos en 6 casos (30%, todos con Neumonitis Intersticial Usual (NIU. Valor predictivo positivo (VPP de la TCAR para detección de quistes: 30% (IC95% 0.13-0.54. Conclusiones: Los trabajos publicados sobre enfermedades intersticiales se basan en la evaluación con cortes axiales de TCAR y la demostración de quistes es de suma importancia para diferenciar NIU de la Neumonía Intersticial No Específica (NINE. En este estudio, se evidencia que la utilización de MinIP con rotación del parénquima redefine 70% de los quistes como bronquioloectasias. Dado el rol cardinal de la TCAR en la evaluación de las intersticiopatías, es importante un estudio prospectivo de seguimiento con mayor número de casos que confirme si son los quistes reales y no los redefinidos como bronquioloectasias los que caracterizan a la NIU.Objective: To demonstrate that axial sections on high-resolution computed tomography (HRCT are insufficient for an accurate examination of diffuse interstitial lung diseases. To further show that minimum intensity projection (MinIP increases diagnosis specificity. Material and methods: Preliminary studies reporting small subpleural cysts were used to select 39 HRCT from 33 patients with confirmed collagen diseases and 6 patients with idiopathic interstitial disease. Patients were reexamined between october 2008 and june 2009. A 16-channel Philips Brillance multislice CT scanner was used. Sections were 1 mm thick de apices a bases. Patients were examined using the common technique, including the MinIP for axial, sagittal and coronal sections, with parenchymal rotation. Cystic areas were carefully examined. Spiral sections were also performed. Results: Of 20 HRCT depicting subpleural cysts with the conventional technique, 14 (70% were bronchiolectases. In 12 cases, images were all bronchiolectases; in the other 2, a prevalence of bronchiolectases and isolated cysts were seen. Real cysts could be confirmed in 6 cases (30%, all of which presented usual interstitial pneumonitis (UIP. The HRCT positive predictive value (PPV for cyst detection was 30% (95% CI 0.13-0.54. Conclusions: Interstitial diseases reports focus on performing axial sections on HRCT, and cyst detection is pivotal to differentiate UIP from NINE. This study reveals that the use of MinIP with parenchymal rotation redefines 70% of cysts as bronchiolectases. Given the key role of HRCT in the examination of interstitial diseases, it is important to carry out a prospective follow-up study with a larger number of cases, in order to confirm whether the UIP is characterized by real cysts or by cysts redefined as bronchiolectases.

  17. En las enfermedades intersticiales difusas,¿todos los quistes son realmente quistes? / Diffuse interstitial diseases: are all cysts real cysts?

    Scientific Electronic Library Online (English)

    Juan Carlos, Spina; Juan Carlos, Spina (h); Ana Josefina, Medina; Cristina, Soler; María Sol, Cormick; María Constanza, Montenegro.

    2010-04-01

    Full Text Available Propósito: Demostrar que los cortes axiales de tomografía computada de alta resolución (TCAR) son insuficientes para una correcta evaluación de las enfermedades pulmonares intersticiales difusas y que adicionar Proyección de Mínima Intensidad (MinIP) aumenta la especificidad del diagnóstico. Materia [...] l y Métodos: Estudios previos donde se observaban quistes pequeños subpleurales se seleccionaron 39 TCAR de 33 pacientes con colagenopatías confirmadas y 6 con enfermedad intersticial idiopática y se los reexaminó entre octubre de 2008 y junio de 2009. El equipo utilizado fue un tomógrafo computado multislice Philips Brillance de 16 canales. Los cortes fueron de 1 mm de espesor, de ápices a bases. La evaluación se realizó con la técnica habitual, adicionando la MinIP en cortes axiales, sagitales y coronales, con rotación del parénquima y especial atención en las áreas que presentaban quistes. Se efectuaron además cortes en espiración. Resultados: De 20 TCAR que mostraban quistes subpleurales con la técnica habitual, 14 (70%) correspondieron a bronquioloectasias. En 12 casos, todas las imágenes eran bronquioloectasias; en 2 casos, ellas predominaban, observándose también quistes aislados. Se pudo definir la existencia de quistes verdaderos en 6 casos (30%), todos con Neumonitis Intersticial Usual (NIU). Valor predictivo positivo (VPP) de la TCAR para detección de quistes: 30% (IC95% 0.13-0.54). Conclusiones: Los trabajos publicados sobre enfermedades intersticiales se basan en la evaluación con cortes axiales de TCAR y la demostración de quistes es de suma importancia para diferenciar NIU de la Neumonía Intersticial No Específica (NINE). En este estudio, se evidencia que la utilización de MinIP con rotación del parénquima redefine 70% de los quistes como bronquioloectasias. Dado el rol cardinal de la TCAR en la evaluación de las intersticiopatías, es importante un estudio prospectivo de seguimiento con mayor número de casos que confirme si son los quistes reales y no los redefinidos como bronquioloectasias los que caracterizan a la NIU. Abstract in english Objective: To demonstrate that axial sections on high-resolution computed tomography (HRCT) are insufficient for an accurate examination of diffuse interstitial lung diseases. To further show that minimum intensity projection (MinIP) increases diagnosis specificity. Material and methods: Preliminary [...] studies reporting small subpleural cysts were used to select 39 HRCT from 33 patients with confirmed collagen diseases and 6 patients with idiopathic interstitial disease. Patients were reexamined between october 2008 and june 2009. A 16-channel Philips Brillance multislice CT scanner was used. Sections were 1 mm thick de apices a bases. Patients were examined using the common technique, including the MinIP for axial, sagittal and coronal sections, with parenchymal rotation. Cystic areas were carefully examined. Spiral sections were also performed. Results: Of 20 HRCT depicting subpleural cysts with the conventional technique, 14 (70%) were bronchiolectases. In 12 cases, images were all bronchiolectases; in the other 2, a prevalence of bronchiolectases and isolated cysts were seen. Real cysts could be confirmed in 6 cases (30%), all of which presented usual interstitial pneumonitis (UIP). The HRCT positive predictive value (PPV) for cyst detection was 30% (95% CI 0.13-0.54). Conclusions: Interstitial diseases reports focus on performing axial sections on HRCT, and cyst detection is pivotal to differentiate UIP from NINE. This study reveals that the use of MinIP with parenchymal rotation redefines 70% of cysts as bronchiolectases. Given the key role of HRCT in the examination of interstitial diseases, it is important to carry out a prospective follow-up study with a larger number of cases, in order to confirm whether the UIP is characterized by real cysts or by cysts redefined as bronchiolectases.

  18. Intraosseous epidermoid cysts in the distal phalanx of two dogs

    International Nuclear Information System (INIS)

    Two dogs were presented with a history of lameness associated with swelling of one of the digits. Radiographs of the affected digits revealed an irregularly mineralized, smoothly marginated proliferative bone lesion in the distal phalanx of one dog and a destructive bony lesion in the distal phalanx of the second dog. The differential diagnosis included nail bed carcinoma, malignant melanoma, osteomyelitis, and subungual keratoacanthoma. Radiographic findings and no response to medical treatment resulted in amputation and submission of the digits for a histopathologic diagnosis. Histologic examination of the distal phalanx of the digits revealed benign epidermoid cysts associated with either bony proliferation or osteolysis. Excision of the lesions was curative. This report presents the clinical, radiographic, and histopathologic findings associated with intraosseous epidermoid cysts in the distal phalanx of two dogs

  19. Sublingual Epidermoid Cyst Presenting with Distinctive Magnetic Resonance Imaging Findings

    OpenAIRE

    Yoshida, Naohiro; Kodama, Kozue; Iino, Yukiko

    2014-01-01

    A case of sublingual epidermoid cyst presenting distinctive magnetic resonance imaging (MRI) findings is described. A 39-year-old man presented to our hospital with a three months progressive left submandibular swelling, difficulty moving his tongue, and snoring. Preoperative evaluation with MRI and fine needle aspiration cytology (FNAC) revealed that the heterogeneous cystic lesion contained the squamous cells, which is compatible with ectodermal tissue. The mass was located above the mylohy...

  20. Quiste óseo simple como posible complicacion al tratamiento ortodontico

    Scientific Electronic Library Online (English)

    Alonso, Geraldine; José Maria, González Hernández; Yuli, Moret de González.

    2008-03-01

    Full Text Available El quiste óseo simple, es una cavidad intraósea sin recubrimiento epitelial, tiene una etiología traumática en un 25% de los casos, también puede originarse de un infarto en la médula ósea o del hueso esponjoso, degeneración quística de algún tumor previo o alteración en el proceso de  osificación. [...] Representa del 0,2 al 1% de la patología quística maxilar y se presentan generalmente de forma asintomática en la mandíbula de jóvenes entre los 5 y los 25 años. El pronóstico del quiste óseo simple, tras curetaje  de la cavidad es excelente, incluso para la vitalidad pulpar de los dientes involucrados. Se presenta una revisión de la literatura del quiste óseo simple y su relación al trauma ocasionado por fuerzas excesivas durante el tratamiento de ortodontico. Abstract in english This solitary injury generally appears both sides and in minor frequency, without epithelial cover and surrounded by osseous walls.  It can be empty or liquid content. Frequently, it is not diagnosed by a clinical examination but with a panoramic.  It is asymtomatic, does not produce pulpar alterati [...] ons in the radiography teeth.  It is observed as a well limited radiolucide image.  The biologreal response to the orthodontic treatment does not only include the response of the periodontal ligament, but also the zone of growth outside the dentition, specially in the suture of the upper jaw and in the osseous surface of both sides of the T.M.J.

  1. Sublingual epidermoid cyst presenting with distinctive magnetic resonance imaging findings.

    Science.gov (United States)

    Yoshida, Naohiro; Kodama, Kozue; Iino, Yukiko

    2014-06-18

    A case of sublingual epidermoid cyst presenting distinctive magnetic resonance imaging (MRI) findings is described. A 39-year-old man presented to our hospital with a three months progressive left submandibular swelling, difficulty moving his tongue, and snoring. Preoperative evaluation with MRI and fine needle aspiration cytology (FNAC) revealed that the heterogeneous cystic lesion contained the squamous cells, which is compatible with ectodermal tissue. The mass was located above the mylohyoid muscle and spread to the pharyngeal space. By considering the size, infection history, patient age, and location, the cyst was completely resected under general anesthesia via cervical approach without any complication. Histopathologically, the cyst wall was lined by stratified squamous epithelium with no skin appendage, suggesting an epidermoid cyst. Ultrasound (US), MRI and FNAC were very useful of the preoperative diagnosis for oral and sublingual lesion. The postoperative course was uneventful and without recurrence after 24 months. This case showed that epidermoid cysts formed the rarely heterogeneous cystic tumor and it underlined usefulness of preoperative diagnosis, such as US, MRI and FNAC for oral and sublingual tumor. PMID:25332766

  2. Sublingual epidermoid cyst presenting with distinctive magnetic resonance imaging findings

    Directory of Open Access Journals (Sweden)

    Naohiro Yoshida

    2014-08-01

    Full Text Available A case of sublingual epidermoid cyst presenting distinctive magnetic resonance imaging (MRI findings is described. A 39-year-old man presented to our hospital with a three months progressive left submandibular swelling, difficulty moving his tongue, and snoring. Preoperative evaluation with MRI and fine needle aspiration cytology (FNAC revealed that the heterogeneous cystic lesion contained the squamous cells, which is compatible with ectodermal tissue. The mass was located above the mylohyoid muscle and spread to the pharyngeal space. By considering the size, infection history, patient age, and location, the cyst was completely resected under general anesthesia via cervical approach without any complication. Histopathologically, the cyst wall was lined by stratified squamous epithelium with no skin appendage, suggesting an epidermoid cyst. Ultrasound (US, MRI and FNAC were very useful of the preoperative diagnosis for oral and sublingual lesion. The postoperative course was uneventful and without recurrence after 24 months. This case showed that epidermoid cysts formed the rarely heterogeneous cystic tumor and it underlined usefulness of preoperative diagnosis, such as US, MRI and FNAC for oral and sublingual tumor.

  3. Carcinoma epidermoide primitivo. Presentación de un caso: modelos de diagnóstico y evaluación / Early epidermoid carcinoma. A case presentation

    Scientific Electronic Library Online (English)

    Lidia, Torres Ajá; Julian, Viera Llanes.

    2009-12-01

    Full Text Available El carcinoma epidermoide primitivo es considerado el tumor más raro de la mama, con una incidencia que representa solo del 0,04 al 0,075 % de todos los tumores malignos de mama. Es una variedad de carcinoma metaplásico constituido por células pavimentosas queratinizantes, con presencia inconstante d [...] e elementos fusocelulares sarcomatoides, estos alcanzan grandes volúmenes y se presentan frecuentemente como tumoraciones quísticas que pueden confundirse con un absceso mamario. El caso que se presenta es una paciente femenina de 41 años de edad, de color de piel blanca, residente en el municipio de Cienfuegos que acudió a la consulta de Mastología de la provincia por presentar una tumoración de 5 cms. en el cuadrante superior externo de la mama derecha, de dos meses de evolución. Se realizó exèresis de la tumoración y se recibió informe de la biopsia con el resultado de carcinoma epidermoide poco diferenciado. Actualmente la paciente es seguida por consulta y está libre de metástasis. Por lo inusual del caso se decide su publicación. Abstract in english The early epidermoid carcinoma is considered the strangest breast tumor with an incidence that only represents from 0,04 to 0,075 % out of all malignant tumors of the breast. It is a variety of the metaplastic carcinoma constituted by pavement keratinizing cells with an inconstant presence of fusoce [...] llular sarcomatoid elements, that reach great volume and frequently present as cystic tumours that may be confused with a breast abscess. This is the case of a 41 year-old white female from Cienfuegos municipality, Cuba, who presented to the provincial Mastology consultation because of a two month follow up of a 5 cm tumor in the right outer upper quadrant of her breast. Surgical removal of the tumor was performed and the result of the biopsy revealed a little differentiated epidermoid carcinoma. At present the patient has no metastasis and receives treatment at the outpatient. Its unusual presentation has led this case to be published.

  4. Encefalitis límbica paraneoplásica y carcinoma epidermoide del seno piriforme / Paraneoplastic limbic encephalitis and epidermoid carcinoma of the pyriform sinus

    Scientific Electronic Library Online (English)

    M. A., Sobas; M. A., Galiano Leis; R. de la, Fuente Cid; I., Pereiro Zabala.

    2006-07-01

    Full Text Available La encefalitis límbica paraneoplásica es un síndrome que se caracteriza clínicamente por alteraciones de comportamiento, trastornos de memoria reciente y crisis epilépticas. Presentamos el caso clínico de un varón de 62 años, ex-fumador, que ingresa en UCI por un cuadro de crisis convulsivas, presen [...] tando anteriormente cambios en el carácter. Los estudios practicados resultaron negativos a excepción de LCR con hiperproteinorraquia y RNM que mostraba lesiones en el lóbulo temporal . Una vez descartadas otras posibles etiologías, iniciamos despistaje de neoplasia oculta. No se evidenció tumor en las pruebas de imagen habituales. Los anticuerpos anti-Hu resultaron negativos. Se realizó tomografía de emisión de positrones (TEP) de cuerpo entero que reveló un foco de hipercaptación a nivel faringolaríngeo. La biopsia fue diagnóstica de carcinoma epidermoide del seno piriforme. En nuestro conocimiento es el primer caso de ELP asociada a carcinoma epidermoide del seno piriforme. Abstract in english Paraneoplastic limbic encephalitis is a syndrome characterised by behaviour changes, short-term memory loss and seizures. We report on a case of a 62-year-old man, ex-smoker who was admitted to the Intensive Care Unit with seizures, and who had previously experienced behaviour changes. Tests reveale [...] d nothing notable, except for the CSF examination which revealed elevated protein and MRI findings indicating temporal lobe abnormalities. Once other diagnoses had been ruled out, neoplasm screening was initiated. Conventional imaging failed to identify the tumour. Antineuronal anti-Hu antibodies were negative. Finally, fluorodeoxyglucose (FDG) whole body -PET imaging was carried out revealing a pathologically increased glucose metabolism at the pharynx-larynx level. The biopsy showed an epidermoid carcinoma of the pyriform sinus. To the best of our knowledge, this is the first reported case of an epidermoid carcinoma of the pyriform sinus associated with paraneoplastic limbic encephalitis.

  5. Carcinoma en quiste tirogloso Carcinoma in thyroglosal duct cyst

    Directory of Open Access Journals (Sweden)

    M.E. Storani

    2010-09-01

    Full Text Available El carcinoma diferenciado de tiroides en quiste tirogloso (CaQT es una rara entidad. En diferentes series de pacientes operados por quistes tiroglosos su incidencia fue del 0.7 al 1.07%. Luego de la extirpación del quiste por el procedimiento de Sistrunk, no hay consenso sobre la indicación de tiroidectomía total, radioablación y/o terapéutica supresiva con levotiroxina. El objetivo del Departamento de tiroides de SAEM, fue evaluar: formas de presentación, evolución clínica, métodos diagnósticos de utilidad y tratamiento para consensuar futuras conductas. Material y Métodos: Estudio multicéntrico, retrospectivo en 22 pacientes entre 10 a 69 años, 15 mujeres y 7 varones. Resultados: El tamaño de los quistes osciló entre 1 y 8 cm (Mediana= 3.0 cm, ? ± DS= 3.7 ± 2.2 cm. La mitad de los pacientes presentó crecimiento del quiste en los 6 meses previos a la cirugía. La punción resultó sospechosa en 2/5 quistes y positiva en uno. La ecografía tiroidea evidenció nódulos en 4/13 casos (30%. Se realizó tiroidectomía en 17/22 pacientes (total: 15 y subtotal: 2. La histología del CaQT demostró carcinoma papilar en 21 y carcinoma folicular en uno. Hubo coexistencia de cáncer intratiroideo en el 23.5% de los casos, ninguno multicéntrico. Dos pacientes presentaron metástasis ganglionares y otro tuvo compromiso muscular (ninguno de ellos coexistió con cáncer intratiroideo. Se radioablacionó a 13 pacientes. En 9/11 pacientes la tiroglobulina permaneció indetectable durante el seguimiento (1 a 14 años. Conclusiones: 1 Realizar ecografía de cuello y punción ecoguiada a todo paciente con quiste tirogloso. 2 En caso de CaQT combinar simultáneamente tiroidectomía total y procedimiento de Sistrunk. 3 Evaluar radioablación complementaria y tratamiento supresivo con levotiroxina en cada caso. 4 Efectuar el seguimiento tal como en los carcinomas ortotópicos.Differentiated thyroid carcinoma (DTC in thyroglosal duct cyst (TGDC is rare, ranging from 0.7 to 1.07% in different series. After the surgery of choice (Sistrunk procedure the other alternative treatments such as thyroidectomy (Tx, radioiodine and L-T4 therapy are controversial. OBJECTIVE: to evaluate several and controversial aspects in the largest series of DTC in TGDC reported in the literature. Subjects and methods: retrospective multicentric study: n= 22, aged 10-69 yrs. (15 females and 7 men who underwent the Sistrunk procedure for TGDC. Results: none of the TGDC was less than 1 cm (median 3.0 cm, ?±SD= 3.7 ± 2.2cm. In half of them there was an increased cystic size in the last 6 months before surgery. Cyst FNA was suspicious in 2/5 and positive in one, whereas the histological diagnosis of the operated TGCD was papillary cancer in 21 and 1 follicular carcinoma. Thyroid ultrasound (US (n=13 showed nodules in 30% of the cases. Tx was performed in 17/22 (total: 15, subtotal: 2. Thyroid DTC coexisted in 4/17 (23.5%, and was unilateral in all of them. Lymph node metastases were present in 2 adults and muscle involvement was found in the 10-year old girl. None of these 3 patients had overt thyroid lesions. 131-I therapy was performed in 10 patients. In 9 out of 11 subjects Tg remained undetectable during follow-up (1-14yrs.. Persistent high Tg was present in one case without thyroid DTC. Conclusions: 1 Ultrasonography and FNAB should be performed to every patient with thyroglossal duct cyst 2 In case of TGDC, total Tx and Sistrunk's procedure should be simultaneously combined 3 131-I therapy and L-T4 suppressive treatment should be evaluated in every case 4 Follow-up as in the DTC.

  6. Carcinoma en quiste tirogloso / Carcinoma in thyroglosal duct cyst

    Scientific Electronic Library Online (English)

    M.E., Storani; A.M., Vázquez; G.N., Alcaraz; S., Gutiérrez; A., Gauna; M., Silva Croome; H., Niepomniszcze; M., Abalovich; C., Cabezón; S., Deutsch; A.M., Orlandi.

    2010-09-01

    Full Text Available El carcinoma diferenciado de tiroides en quiste tirogloso (CaQT) es una rara entidad. En diferentes series de pacientes operados por quistes tiroglosos su incidencia fue del 0.7 al 1.07%. Luego de la extirpación del quiste por el procedimiento de Sistrunk, no hay consenso sobre la indicación de tiro [...] idectomía total, radioablación y/o terapéutica supresiva con levotiroxina. El objetivo del Departamento de tiroides de SAEM, fue evaluar: formas de presentación, evolución clínica, métodos diagnósticos de utilidad y tratamiento para consensuar futuras conductas. Material y Métodos: Estudio multicéntrico, retrospectivo en 22 pacientes entre 10 a 69 años, 15 mujeres y 7 varones. Resultados: El tamaño de los quistes osciló entre 1 y 8 cm (Mediana= 3.0 cm, ? ± DS= 3.7 ± 2.2 cm). La mitad de los pacientes presentó crecimiento del quiste en los 6 meses previos a la cirugía. La punción resultó sospechosa en 2/5 quistes y positiva en uno. La ecografía tiroidea evidenció nódulos en 4/13 casos (30%). Se realizó tiroidectomía en 17/22 pacientes (total: 15 y subtotal: 2). La histología del CaQT demostró carcinoma papilar en 21 y carcinoma folicular en uno. Hubo coexistencia de cáncer intratiroideo en el 23.5% de los casos, ninguno multicéntrico. Dos pacientes presentaron metástasis ganglionares y otro tuvo compromiso muscular (ninguno de ellos coexistió con cáncer intratiroideo). Se radioablacionó a 13 pacientes. En 9/11 pacientes la tiroglobulina permaneció indetectable durante el seguimiento (1 a 14 años). Conclusiones: 1) Realizar ecografía de cuello y punción ecoguiada a todo paciente con quiste tirogloso. 2) En caso de CaQT combinar simultáneamente tiroidectomía total y procedimiento de Sistrunk. 3) Evaluar radioablación complementaria y tratamiento supresivo con levotiroxina en cada caso. 4) Efectuar el seguimiento tal como en los carcinomas ortotópicos. Abstract in english Differentiated thyroid carcinoma (DTC) in thyroglosal duct cyst (TGDC) is rare, ranging from 0.7 to 1.07% in different series. After the surgery of choice (Sistrunk procedure) the other alternative treatments such as thyroidectomy (Tx), radioiodine and L-T4 therapy are controversial. OBJECTIVE: to e [...] valuate several and controversial aspects in the largest series of DTC in TGDC reported in the literature. Subjects and methods: retrospective multicentric study: n= 22, aged 10-69 yrs. (15 females and 7 men) who underwent the Sistrunk procedure for TGDC. Results: none of the TGDC was less than 1 cm (median 3.0 cm, ?±SD= 3.7 ± 2.2cm). In half of them there was an increased cystic size in the last 6 months before surgery. Cyst FNA was suspicious in 2/5 and positive in one, whereas the histological diagnosis of the operated TGCD was papillary cancer in 21 and 1 follicular carcinoma. Thyroid ultrasound (US) (n=13) showed nodules in 30% of the cases. Tx was performed in 17/22 (total: 15, subtotal: 2). Thyroid DTC coexisted in 4/17 (23.5%), and was unilateral in all of them. Lymph node metastases were present in 2 adults and muscle involvement was found in the 10-year old girl. None of these 3 patients had overt thyroid lesions. 131-I therapy was performed in 10 patients. In 9 out of 11 subjects Tg remained undetectable during follow-up (1-14yrs.). Persistent high Tg was present in one case without thyroid DTC. Conclusions: 1) Ultrasonography and FNAB should be performed to every patient with thyroglossal duct cyst 2) In case of TGDC, total Tx and Sistrunk's procedure should be simultaneously combined 3) 131-I therapy and L-T4 suppressive treatment should be evaluated in every case 4) Follow-up as in the DTC.

  7. Studies of testicular function after treatment for testicular tumor, 1

    International Nuclear Information System (INIS)

    Recently, the treatment for testicular tumor has improved. Preservation of testicular function in the treatment of testicular tumor is important, because the majority of the patients are young. We investigated the testicular function of patients with testicular tumor before, during and after treatment. As a part of this study, the fertility of patients with testicular tumor before and after treatment was evaluated. 1. Fourteen of 78 married patients (18 %) showed sterility for two or more years before treatment. 2. When semen was examined in 31 patients before treatment, only seven patients (23 %) showed normal sperm counts of more than 40 x 106/ml, and 19 (61.3 %) showed oligospermia or azoospermia with sperm counts of less than 10 x 106/ml. 3. Of 20 patients who underwent retroperitoneal lymphnode dissection, 15 developed ejaculation deficiency. Four other patients also developed ejaculation deficiency but recovered, and three of them rendered their wives pregnant. 4. Of 23 patients given radiotherapy, nine produced children both before and after treatment, nine produced children before treatment but showed sterility after treatment, and five showed sterility both before and after treatment. 5. Examination of semen was performed in 17 patients given radiotherapy and in five given chemotherapy. Many patients developed oligospermia or azoospermia after the treatments, but revealed a tendency to recover with time. Based on the results mentioned above, it is inferred that the ability to produce sperm in patients with testicular tumor after treatment decreases but the decrease tends to recover to normal with time. (author)

  8. Unusual Presentation of a Left Testicular Carcinoid

    OpenAIRE

    Palla, Amruth R.; Hogan, Thomas; Singh, Sindhu

    2012-01-01

    Testicular carcinoid generally presents either with a palpable (painful or painless) or rarely a nonpalpable mass (when it is diagnosed incidentally on scrotal imaging) of the involved testis. An ipsilateral testicular carcinoid presenting exclusively with contralateral testicular symptoms has never been described in the literature to date. We report a case of nonpalpable left testicular carcinoid diagnosed incidentally on a sonogram done for right testicular pain and swelling, with conspicuo...

  9. Testicular cytology in azoospermia

    Directory of Open Access Journals (Sweden)

    Usha Prasad

    2015-06-01

    Results: The commonest group with infertility were in the age group 21-30 years. The testicular size was normal in 87.17% of subjects and 12.82% had small testis. Out of 39 subjects with azoospermia 38.46% subjects had varicocele. Varicocele was commonly associated with duct obstruction. The commonest causes observed in cases with azoospermia were; hypospermatogenesis with maturation arrest (4/39,10.25%, duct obstruction (12/39,30.76%, maturation arrest (7/39,17.94%, testicular atrophy (10/39,25.64% and sertoli cell only syndrome (2/39,5.12%. In the present study diagnostic accuracy was 89.18%. Conclusions: Fine needle aspiration cytology is as informative as biopsy and can be done as a routine procedure. It helps us in ruling out obstructive and non-obstructive causes for azoospermia. In cases where FNAC shows normal spermatogenesis with azoospermia, biopsy and Doppler study is indicated to rule out duct obstruction which can be corrected surgically. It is a simple and cost effective. [Int J Reprod Contracept Obstet Gynecol 2015; 4(3.000: 647-652

  10. Asymptomatic intradiploic epidermoid cyst eroding frontal bone in a patient with craniosynostosis.

    Science.gov (United States)

    Yildiz, Kemalettin; Sagir, Haci Ömer; Tosuner, Zeynep; Canter, Halil Ibrahim; Guneren, Ethem

    2015-01-01

    Epidermoid cyst located in cranium is uncommon and usually diagnosed with a growing mass leading to symptoms. Asymptomatic intradiploic epidermoid cyst has not been reported yet. In this study, incidental diagnosis of asymptomatic cyst and potential impact of that cyst on surgical planning of a patient with craniosynostosis are presented. PMID:25569418

  11. Cranial cystic epidermoid: report of two cases and review of the literature

    International Nuclear Information System (INIS)

    Intercranial epidermoid tumours are benign lesions of congenital origin that are potentially curable. Although computerized axial tomography (CT) and magnetic resonance imaging (MRI) are usually diagnostic, a few atypical features sometimes make pre-operative diagnosis difficult. Two cases of cystic epidermoids with peripheral ring enhancement are reported. Relevant literature has been reviewed. 15 refs., 2 figs

  12. Carcinoma epidermoide de canal anal estádio IV: complicações clínicas de doença avançada Epidermoid carcinoma of anal canal stage IV: clinical complications of advanced disease

    OpenAIRE

    Fernanda Bellotti Formiga; Alessandra Vicentini Credidio; Daltro Lemos Rosa; José César Assef; Chia Bin Fang; Peretz Capelhuchnik; Wilmar Artur Klug

    2010-01-01

    O carcinoma anal é uma entidade rara que representa 4% dos tumores malignos da região anorretal, dentro os quais o carcinoma epidermoide constitui o tipo histológico mais comum. É relatado o caso de um paciente masculino, 54 anos, com carcinoma epidermoide de canal anal localmente avançado e com metástases ósseas no diagnóstico, feito após complicação infecciosa local com repercussão sistêmica. Descrevemos a evolução do paciente após o diagnóstico da neoplasia e as dificuldades de manejo clín...

  13. Quiste óseo aneurismático / Kyste osseux anévrysmal / Aneurysmatic bone cyst

    Scientific Electronic Library Online (English)

    Luis, Varela Ravelo; Ernesto, Fleites Marrero; René, Rubinos Ruiz; Jorge, Riaños; Eduardo, Albisu.

    2007-12-01

    Full Text Available Se presentó un caso de quiste óseo aneurismático vertebral lumbar y su propuesta de tratamiento, de una paciente femenina de 8 años procedente de Venezuela, que después de una caída comenzó a notar aumento de volumen con dolor ligero en región lumbar. La paciente ha tenido una evolución favorable. [...] Abstract in english The case of a Venezuelan 8-year-old female with vertebrolumbar aneurysmatic bone cyst, as well as the proposed treatment were presented. After falling, the patient began to observe a volume increase with mild pain in the lumbar region. The patient has had a favorable evolution. [...

  14. Quistes epididimarios en la infancia / Epididymal cysts in childhood

    Scientific Electronic Library Online (English)

    Francisca Silvia, Chillón Sempere; Carlos, Domínguez Hinarejos; Agustín, Serrano Durbá; Francisco, Estornell Moragues; Mario, Martínez-Verduch; Francisco, García Ibarra.

    2005-05-01

    Full Text Available OBJETIVO: Hemos realizado una revisión retrospectiva de los casos atendidos en los últimos 5 años; se han recogido un total de 15 casos. Los quistes simples de epidídimo son patología poco frecuente en la infancia diagnosticándose la mayoría en la pubertad. Actualmente y debido a la escasa casuístic [...] a no existe consenso en la terapéutica más adecuada. METODOS/RESULTADOS: La edad media de presentación fue de 11,5 años (1-16). El 50% fueron diagnosticados de forma incidental y un 29% cursó con aumento de tamaño escrotal. El 46% de los casos presentaban varicocele izquierdo asociado (n=6) y un 26% presentaba antecedentes de orquiepididimitis. El diagnóstico se basó en la exploración física con confirmación ecográfica. Un 40 % fue tratado quirúrgicamente y el resto fue subsidiario de tratamiento conservador sin constatarse la presencia de complicaciones en estos en los controles posteriores. CONCLUSIONES: Dada la benignidad y la buena evolución de todos los casos de quistes de epidídimo tratados de forma conservadora, y la ausencia de beneficio con el tratamiento quirúrgico, creemos que el tratamiento debe ser conservador con controles clínicos y ecográficos reservando el tratamiento quirúrgico para aquellos quistes que presenten complicaciones. La frecuente asociación encontrada entre el quiste epididimario y el varicocele responde a una coincidencia de ambas patologías en la edad peripuberal. Abstract in english OBJECTIVES: To retrospectively review all cases of epididymal cysts registered over the last five years; 15 cases have been included. Simple epididymal cysts are a rare pathology in childhood, being most of them diagnosed in puberty. Currently, due to the scarce case series, there is not consensus a [...] bout the most adequate therapy. METHODS/RESULTS: Mean age at presentation was 11.5 yr. (1-16). 50% were diagnosed incidentally and 29% presented increased scrotal size. 46% of the cases had associated left varicocele (n = 6) and 26% had history of orchiepididymitis. Diagnosis was based on physical examination and confirmed by ultrasound. 40% of the patients underwent surgery and the remainder received conservative treatment without evidence of complications on follow-up. CONCLUSIONS: Due to the benign character and good evolution of all cases of epididymal cysts treated conservatively and the absence of benefit after surgical treatment, we believe that management should be conservative with clinical and ultrasound controls, leaving surgery for cysts with complications. The frequent association between epididymal cysts and varicocele is related to coincidence of both pathologies in the prepuberal age.

  15. JAMA Patient Page: Testicular Cancer

    Science.gov (United States)

    Common Sites of Testicular Cancer Metastases Lung Metastases Retroperitoneal Metastasis TUMOR CROSS SECTION NORMAL LEFT TESTICLE RIGHT TESTICLE Computed tomography and ultrasound images: Ariadne M. Bach, MD/Robert J. Motzer, ...

  16. MRI of testicular disease

    International Nuclear Information System (INIS)

    The value of T1-weighted sequences after intravenous administration of Gd-DTPA and of T2-weighted sequences was compared in 43 patients suspected of having scrotal abnormalities. T2-weighted sequences gave better demonstration of the tunica albuginea and better contrast between tumor and parenchyma. The two techniques were equally sensitive for demonstrating testicular tumors but orchitis was better demonstrated on the contrast enhanced sequences. Motion artifacts were less marked in the T1-weighted sequences with contrast enhancement. In selected cases, contrast enhancement may be a valuable addition to native protocols. Our experience has indicated that MRI provides specific findings in cases of orchitis which are clinically atypical; this facilitates the decision to conservative treatment and prevents unnecessary exploration of the testes. (orig.)

  17. Testicular metastasis of prostatic cancer.

    Science.gov (United States)

    Smaali, Chemsedine; Gobet, Francoise; Dugardin, Fabrice; Pfister, Christian

    2010-02-01

    Secondary testicular tumors are rare, we report a case of a solitary testicular metastasis of prostate cancer in 58-year-old man treated using hormonal therapy associated with radiotherapy. Ultrasound is the imaging modality of choice, but metastasis might be difficult to differentiate from primary tumors. The diagnosis confirmed by histologic examination includes routine microscopic and immunohistochemical findings, and therefore systemic treatment was required. PMID:19913885

  18. Quiste ovárico fetal: diagnóstico prenatal y manejo quirúrgico postnatal exitoso

    Directory of Open Access Journals (Sweden)

    Alejandra Cabellos M

    2012-01-01

    Full Text Available Los quistes ováricos son el tumor abdominal mas frecuente en las recién nacidas. Presentan complicadones agudas y a largo plazo. La más frecuente es la torsión anexial que presenta dificultades diagnósticas en la etapa neonatal. El diagnóstico prenatal es fundamental para el manejo oportuno de las pacientes. Existen diferentes alternativas terapéuticas donde la cirugía mínimamente invasiva y conservadora juega un importante rol. Presentamos el caso de una recién nacida macrosómica con diagnóstico prenatal de quiste ovárico no complicado que sufrió torsión durante los primeros días de vida y se resolvió exitosamente en forma quirúrgica conservadora gracias a un manejo multidisciplinario.Ovarian cysts are the most common abdominal tumor in female newborns. They could develop acute or long term complications. The most frequent complication is adnexal torsion, which presents with diagnostic difficulties in the neonatal period. Prenatal diagnosis is essential for the prompt management of patients. There are different treatment options where conservative and minimally invasive surgery plays an important role. We report a female newborn with prenatal diagnosis of macrosomia and uncomplicated ovarian cyst, which suffered adnexal torsion during the first days of life and was successfully resolved with a conservative surgical management by a multidisciplinary staff.

  19. Quiste ovárico fetal: diagnóstico prenatal y manejo quirúrgico postnatal exitoso

    Scientific Electronic Library Online (English)

    Alejandra, Cabellos M; Isabel, Cavieres C; Pablo, Zarges T; Mario, Gajardo C; Richard, Vega D.

    Full Text Available Los quistes ováricos son el tumor abdominal mas frecuente en las recién nacidas. Presentan complicadones agudas y a largo plazo. La más frecuente es la torsión anexial que presenta dificultades diagnósticas en la etapa neonatal. El diagnóstico prenatal es fundamental para el manejo oportuno de las p [...] acientes. Existen diferentes alternativas terapéuticas donde la cirugía mínimamente invasiva y conservadora juega un importante rol. Presentamos el caso de una recién nacida macrosómica con diagnóstico prenatal de quiste ovárico no complicado que sufrió torsión durante los primeros días de vida y se resolvió exitosamente en forma quirúrgica conservadora gracias a un manejo multidisciplinario. Abstract in english Ovarian cysts are the most common abdominal tumor in female newborns. They could develop acute or long term complications. The most frequent complication is adnexal torsion, which presents with diagnostic difficulties in the neonatal period. Prenatal diagnosis is essential for the prompt management [...] of patients. There are different treatment options where conservative and minimally invasive surgery plays an important role. We report a female newborn with prenatal diagnosis of macrosomia and uncomplicated ovarian cyst, which suffered adnexal torsion during the first days of life and was successfully resolved with a conservative surgical management by a multidisciplinary staff.

  20. Epidermoid gastric cancer review literature a case study

    International Nuclear Information System (INIS)

    Full text: introduction. epidermoid epidemiologic ally gastric cancer etiology is extremely uncommon forming a 0.04 to 0.07% of cases. target. reviewing the literature from a clinical case of a female patient 60 years epidermoid carrier loco regionally advanced gastric cancer. methodology and methods. analyze the case of gastric cancer squamous which TB diagnosed n2 m0 be a eiiic. results. the case was presented as an atypical dyspepsia was diagnosed with cancer gastric squamous after taking multiple biopsies. diagnosis is confirmed and the checked laparoscopically resectable liver infiltration, commitment vascular and pancreatic seen by ct scan. it was decided to establish treatment palliative chemotherapy based on docetaxel, 5-fluorouracil and cisplatin that fails to receive and who dies of massive haematemesis. conclusions. it is well established the pathogenesis of this disease. in series reported we found a higher incidence in males, with a median age presentation at age 64. the most common is the fun dus and diagnosis in advanced stages is most prevalent. being a rare histological subtype as there is no evidence to support a massed different therapeutic adenocarcinoma

  1. Isodense epidermoid cyst in the pineal region. Case report

    Energy Technology Data Exchange (ETDEWEB)

    Yamanouchi, Yasuo; Takahara, Nobuhiko; Kawamura, Yasuo; Matsumura, Hiroshi

    1985-02-01

    A 69-year-old male was admitted complaining of gait disturbances and diplopia, 2.5 years after an episode of serous meningitis. Neurological examination on admission disclosed Parinaud's sign, unsteady gait and dysdiadochokinesis on the left side. A striking finding on the computerized tomography (CT) was the left to right shift of the posterior portion of the third ventricle without visualization of the quadrigeminal and ambient cisterns, which were almost completely occupied by an isodense mass accompanied by high dense flecks and a low dense part. Enhanced CT showed positive enhancement in the vicinity of the pineal calcification. By the suboccipital supracerebellar approach, an encapsulated mass containing brownish yellow fluid was subtotally removed and a histological examination of it revealed epidermoid tissue and hemosiderin deposits in the solid portion. Few reports of isodense epidermoid cysts have so far been found in the literature giving a full explanation for this unusual CT attenuation value. Based on the clinical course and histology of this case, the pathogenesis of the unusual density is discussed along the following lines: The mixture of the low dense factor due to cholesterin and the high dense factor due to prior bleeding is believed to result in the isodense attenuation value in the liquid portion. Also, in the solid part, a microscopically mixed texture of deposited hemosiderin and cholesterin clefts in the inflammatory granulomatous tissue could explain its density on the CT scan.

  2. Abordaje endoscópico de los quistes gliales pineales sintomaticos

    Scientific Electronic Library Online (English)

    Gloria, Villalba Martínez; Luis Alberto, Caral Pons; Bartolomeu, Fiol Busquets; Neus, Fabregas Juliá; Teresa, Ribalta Ribas; Teresa, Boget Prats; Antoni, Raspall Borell; Enric, Ferrer Rodríguez.

    2009-12-01

    Full Text Available Objetivo. Los quistes gliales pineales (QGP) son infrecuentes. El manejo quirúrgico de estos quistes no está consensuado. En la literatura se recogen 18 casos tratados por vía endoscópica. El objetivo de este trabajo es contribuir con nuestra experiencia en el tratamiento endoscópico de los QGP. Mat [...] erial y método. Entre 1999 y 2004, cinco pacientes con QGP sintomáticos, con o sin hidrocefalia, se trataron mediante vintriculostomía premamilar endoscópica (VPE) y fenestración del quiste. Se utilizó un endoscopio rígido, con sistema de neuronavegación en los casos sin hidrocefalia. Resultados. En el período de seguimiento (de 6 meses a 4 años) se recoge una resolución clínica en 4 casos y una disminución del tamaño del quiste en todos los casos. Todas las VPE fueron permeables en el seguimiento. No hubo déficits clínicos permanentes en ningún caso. Discusión. No existe en la literatura un acuerdo en el mejor tratamiento quirúrgico de los QGP. A pesar de la gran aceptación de la vía endoscópica, un gran número de autores abogan por una cirugía abierta o por una cirugía extereotáxica como la mejor opción. Además, existen algunas diferencias en el manejo quirúrgico endoscópico según ofrece la literatura. Conclusión. La VPE con la fenestración del quiste es un tratamiento eficiente debido a la baja morbilidad y a la eficacia en la resolución clínica y radiológica de los QGP con o sin hidrocefalia. La cirugía abierta, especialmente con la ayuda endoscópica, podría ser un tratamietno de segunda elección, y la cirugía estereotáxica debería abandonarse en estos casos. Abstract in english Objetive. Sympotomatic glial pineal cyst (GPC) are unfrequent. Surgical management of these cysts is not consensed. In the literature there are 18 cases reported treated by endoscopic approach. The purpose of this study is to contribute with our experience to the endoscopic treatment of the GPC. Mat [...] erials and Methods. Between 1999 and 2004, five patients with GPC underwent an endoscopic third ventriculostomy (ETV) and cyst fenestration. We have used a rigid endoscope, with neuronavegation system in the cases without hydrocephalus. Results. In the follow-up period ranged from 6 months to 4 tears we have reported: clinical resolution in four cases and cyst size decrease in all cases. All the ETV have been patent. There was not perman ent morbility and not surgery related death. Discussion. An agreement doesn't exist in the literature about the better treatment of the surgery or by stereotaxy as the best treatment. There are great differences in the surgical management between the 18 endoscopic cases reported in the literature, and also in relation with our cases. Conclusion. The ETV with endoscopic cyst fenestration is an efficient treatment due to the low morbidity and the effectiveness in the treatment of the GPC with or without hydrocephalus. The open surgery (specially with the endoscope assisting microneurosurgery) wolud be a second choice technique, and the stereotactic surgery must be abandoned.

  3. Do We Know What Causes Testicular Cancer?

    Science.gov (United States)

    ... Next Topic Can testicular cancer be prevented? Do we know what causes testicular cancer? The exact cause ... cell, half of which are from each parent. We usually look like our parents because they are ...

  4. Epidermoid cyst of the floor of the mouth. A case report and literature review

    Directory of Open Access Journals (Sweden)

    Rojas-Madrigal A

    2012-02-01

    Full Text Available Dermoid and epidermoid cysts are cystic benign, slightly common malformations that may be found in the area of head and neck between 1.6 and 7 %, representing less than 0.01 % of all the cysts of the oral cavity. This pathology is important of the knowledge of the professional in dentistry and medicine to be able to do the early diagnose and the respective treatment. The purpose of this study is the review of the relevant literature of the dermoid and epidermoid cysts and the presentation of a case of epidermoid cyst in floor of mouth in a patient of 13 years and 5 months of age.

  5. Congenital epidermoid cyst results in muscle fusion defect in the upper lip.

    Science.gov (United States)

    Dogan, Fatih; Bucak, Ibrahim Hakan

    2014-01-01

    Epidermoid cysts are rarely detected malformations in the oral cavity. Their development sites are the sublingual, submaxillary, and submandibular spaces. In this paper, we report a three-month-old infant who was admitted to our hospital due upper lip swelling. Magnetic resonance imaging showed that she had a two-centimeter cystic lesion and fusion defects of orbicularis oris muscle. The cyst was surgically removed and histopathological diagnosis was "epidermoid cyst." In recent literature, we could not find reports related to orbicularis oris muscle fusion defects because of epidermoid cyst. PMID:25628908

  6. Histological evidence of testicular dysgenesis in contralateral biopsies from 218 patients with testicular germ cell cancer

    DEFF Research Database (Denmark)

    Hoei-Hansen, Christina E; Holm, Mette; Rajpert-De Meyts, Ewa; Skakkebæk, Niels Erik

    2003-01-01

    This study was prompted by a hypothesis that testicular germ cell cancer may be aetiologically linked to other male reproductive abnormalities as a part of the so-called 'testicular dysgenesis syndrome' (TDS). To corroborate the hypothesis of a common association of germ cell cancer with testicular dysgenesis, microscopic dysgenetic features were quantified in contralateral testicular biopsies in patients with a testicular germ cell tumour. Two hundred and eighty consecutive contralateral testic...

  7. 21 CFR 876.3750 - Testicular prosthesis.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Testicular prosthesis. 876.3750 Section 876.3750...) MEDICAL DEVICES GASTROENTEROLOGY-UROLOGY DEVICES Prosthetic Devices § 876.3750 Testicular prosthesis. (a) Identification. A testicular prosthesis is an implanted device that consists of a solid or gel-filled...

  8. Intradural Epidermoid Cyst at Conus Medullaris and Cauda Equina of the Spine: A Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Mn Woo; Lee, Ji Hae; Cho, Woo Ho [Dept. of Radiology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul (Korea, Republic of)

    2012-02-15

    Spinal epidermoid cysts occur as a result of anomalous implants of epidermal cells within the spinal cord. Spinal epidermoid cysts comprise < 1% of all intraspinal mass lesions and may be congenital or acquired. Congenital lesions usually occur at conus or cauda equina, and the latter usually occur at lower lumbar spine. The typical MR appearance of a spinal epidermoid cyst is a hypointense signal lesion on T1-weighted images and a hyperintense signal lesion on T2-weighted images. However, atypical imaging features also have been reported. In this article, we report atypical MR findings of an intradural epidermoid cyst at conus medullaris and cauda equina of the spine that was caused by internal cystic hemorrhage.

  9. A CHEESY AFFAIR! - REPORT OF A CASE OF AN EPIDERMOID CYST OF PAROTID

    Directory of Open Access Journals (Sweden)

    Balasubramanian Thaigarajan

    2013-06-01

    Full Text Available This article is a report of a case of epidermoid cyst of the deep lobe of the left parotid, being reported and described for the benefit of the readers in view of the rarity of the condition.

  10. Cáncer de quiste en conducto tirogloso / Thyroglossal duct cyst cancer

    Scientific Electronic Library Online (English)

    Manuel Francisco, Jiménez-Navarrete; Laura, Ulate-Oviedo; María, Aguilar-Aráuz; Gerardo, Sáenz-Batalla.

    2013-12-01

    Full Text Available El quiste del conducto tirogloso es una de las anomalías del desarrollo que se presentan más frecuentemente en el cuello. La presencia en este de carcinoma aislado o concomitante con cáncer en tiroides, es muy infrecuente. Se expone aquí el caso de una paciente joven que se presentó con esta entidad [...] . Se describe su presentación y manejo. Actualmente sigue su control en el Servicio de Endocrinología del Hospital San Vicente de Paúl, Heredia, Costa Rica. Abstract in english Thyroglossal duct cyst cancer is one of the developmental anomalies that not occur frequently in the neck. The presence of isolated or concomitant thyroid cancer is unusual. We present the case of a young female patient with this condition. Presentation and management are described. The Endocrinolog [...] y Service of the San Vicente de Paul Hospital is presently following her case.

  11. Quistes solitarios no parasitarios del hígado: Presentación de 9 casos

    Scientific Electronic Library Online (English)

    Eddy, Sierra Enrique; Javier, Vázquez Roque; Gilberto, Martínez Ramos.

    1999-08-01

    Full Text Available Se estudian 9 pacientes intervenidos quirúrgicamente en los hospitales Clinicoquirúrgico Provincial Docente y Militar "Comandante Manuel Fajardo", ambos de Santa Clara, por presentar quiste solitario no parasitario del hígado. La edad de presentación predominante fue después de los 60 años, y el sex [...] o femenino el más afectado. Siete de los quistes se localizaron en el lóbulo derecho, y 2 en el lóbulo izquierdo del hígado. El dolor abdominal y la tumoración palpable fueron los aspectos más llamativos en el cuadro clínico y el examen físico. La laparoscopia, el ultrasonido abdominal y la tomografía axial computadorizada (TAC) constituyeron los exámenes más útiles para el diagnóstico. La cistoyeyunostomía fue la técnica quirúrgica más utilizada. En 3 pacientes se presentaron complicaciones, para el 33,3 % y 1 falleció, lo que representa el 11,1 % de mortalidad Abstract in english 9 patients that were operated on at the Provincial Clinical and Surgical Teaching Hospital and at the "Comandante Manuel Fajardo" Military Hospital, both in Santa Clara, for presenting solitary nonparasitic hepatic cyst were studied. It appeared mainly in patients over 60, and females were the most [...] affected. 7 of the cysts were located in the right lobule and 2 in the left lobule of the liver. Abdominal pain and palpable tumors were the most important aspects in the clinical picture and in the physical examination. Laparoscopy, abdominal ultrasound and CAT were the most useful tests for the diagnosis. Cystojejunostomy was the most used surgical technique. 3 patients had complications, accounting for 33.3 %, and 1 died, which represents 11.1 % of mortality

  12. Congenital Epidermoid Cyst Results in Muscle Fusion Defect in the Upper Lip

    OpenAIRE

    Dogan, Fatih; Bucak, Ibrahim Hakan

    2014-01-01

    Epidermoid cysts are rarely detected malformations in the oral cavity. Their development sites are the sublingual, submaxillary, and submandibular spaces. In this paper, we report a three-month-old infant who was admitted to our hospital due upper lip swelling. Magnetic resonance imaging showed that she had a two-centimeter cystic lesion and fusion defects of orbicularis oris muscle. The cyst was surgically removed and histopathological diagnosis was “epidermoid cyst.” In recent literature, w...

  13. Varicocele testicular en adolescentes / Testicular varicocele in adolescent

    Scientific Electronic Library Online (English)

    Daniel, Vásquez E; Carolina, Díaz; Zenen, Carmona; Fernando, Vásquez R.

    2009-12-01

    Full Text Available El varicocele testicular es una patología asociada a la infertilidad del varón. Su mayor prevalencia se presenta en la adolescencia y existen reportes que sugieren que desde esta edad el desarrollo de la espermatogénesis de los adolescentes con varicocele se encuentra comprometido en comparación con [...] los que no lo tienen. Hay que tener presente dos situaciones: una relacionada con las causas por las cuales se presentan las varices y el reflujo venoso en las venas testiculares y su tratamiento, y otra, el daño que ocasionan las varices en la espermatogénesis. Este artículo presenta una revisión de los hallazgos más importantes que explican los mecanismos de la alteración de la fertilidad del varón adolescente que presenta varicocele, por lo que se hace necesario realizar otros estudios que complementen estos hallazgos. Abstract in english The testicular varicocele is a pathology associated with male infertility. Its highest prevalence occurs in adolescence and there are reports that suggest that from this age the development of spermatogenesis in adolescents with varicocele is compromised compared with those without. It is necessary [...] to have present two situations: one related to the causes which have varicose veins and venous reflux in the testicular veins and their treatment and other damage caused varicose veins in spermatogenesis. This article presents a review of the most important findings that explain the mechanisms of the impaired fertility of male adolescents with varicocele

  14. Diffusion tensor mode in imaging of intracranial epidermoid cysts: one step ahead of fractional anisotropy

    Energy Technology Data Exchange (ETDEWEB)

    Jolapara, Milan; Kesavadas, Chandrasekharan; Saini, Jitender; Patro, Satya Narayan; Gupta, Arun Kumar; Kapilamoorthy, Tirur Raman; Bodhey, Narendra [Sree Chitra Tirunal Institute for Medical Sciences and Technology, Department of Imaging Sciences and Interventional Radiology, Trivandrum (India); Radhakrishnan, V.V. [Sree Chitra Tirunal Institute for Medical Sciences and Technology, Department of Pathology, Trivandrum (India)

    2009-02-15

    The signal characteristics of an epidermoid on T2-weighted imaging have been attributed to the presence of increased water content within the tumor. In this study, we explore the utility of diffusion tensor imaging (DTI) and diffusion tensor metrics (DTM) in knowing the microstructural anatomy of epidermoid cysts. DTI was performed in ten patients with epidermoid cysts. Directionally averaged mean diffusivity (D{sub av}), exponential diffusion, and DTM-like fractional anisotropy (FA), diffusion tensor mode (mode), linear (CL), planar (CP), and spherical (CS) anisotropy were measured from the tumor as well as from the normal-looking white matter. Epidermoid cysts showed high FA. However, D{sub av} and exponential diffusion values did not show any restriction of diffusion. Diffusion tensor mode values were near -1, and CP values were high within the tumor. This suggested preferential diffusion of water molecules along a two-dimensional geometry (plane) in epidermoid cysts, which could be attributed to the parallel-layered arrangement of keratin filaments and flakes within these tumors. Thus, advanced imaging modalities like DTI with DTM can provide information regarding the microstructural anatomy of the epidermoid cysts. (orig.)

  15. Carcinoma epidermoide no queratinizante de células grandes y pequeñas en vagina / Large and small cells non-keratinizing epidermoid vaginal carcinoma

    Scientific Electronic Library Online (English)

    Ofelia, Masó Anaya; María Elena, Morales Larramendi; Dolores, Díaz Pérez; Esperanza, Dager Dager; Gloria Adelaida, Bolaños Diego.

    2012-03-01

    Full Text Available Se presentan 5 casos clínicos de pacientes atendidas en la consulta de patología de cuello del Hospital Provincial Ginecoobstétrico "Mariana Grajales Coello" de Santiago de Cuba por presentar sangrado vaginal, dolor en bajo vientre, leucorrea y lesiones vaginales. El estudio anatomopatológico confir [...] mó el diagnóstico de carcinoma de células escamosas o epidermoide. Abstract in english Five case reports of patients who were assisted at the cervix Pathology Department from "Mariana Grajales Coello" Provincial Gynecological Obstetrical Hospital in Santiago de Cuba due to vaginal bleeding, low abdominal pain, leukorrhea and vaginal injuries are presented. The pathological study confi [...] rmed the diagnosis of squamous or epidermoid cells carcinoma.

  16. Drugs Approved for Testicular Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for testicular cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.

  17. Quiste óseo simple de cóndilo mandibular / Simple bone cyst of the mandibular condyle

    Scientific Electronic Library Online (English)

    Julio, Cifuentes; Ariel, Barrera; Daniel, Jerez; Stephanie, Bohmann.

    2015-03-01

    Full Text Available El quiste óseo simple (QOS) es una entidad descrita por primera vez por Lucas en 1929. En 1946, Rushton describió las paredes internas del quiste que consistían en tejido óseo sin contenido patológico o químico. Esta entidad intraósea también es conocida con múltiples sinónimos como quiste óseo soli [...] tario, quiste óseo traumático, quiste óseo hemorrágico, quiste unicameral, cavidad ósea idiopática y cavidad o quiste óseo progresivo. Cuando afecta a los maxilares suelen ser asintomáticos, siendo su diagnóstico habitualmente un hallazgo radiológico. Las áreas comúnmente afectadas son entre los caninos inferiores y la región de los terceros molares y, en segundo lugar, la sínfisis mandibular. Los QOS de cóndilo son raros, habiéndose referido previamente 15 casos en la literatura. En el caso referido se describirá el tratamiento y se hará una revisión de la enfermedad. Abstract in english Simple bonecysts (SBC) have been a recognized entity since 1929, when they were first described by Lucas. In 1946, Rushton described the inner walls of the cyst, consisting of bone and no pathological or chemical content. This intraosseous entity, is also known by a variety of synonyms including sol [...] itary bone cyst, traumatic bone cyst, hemorrhagic bone cyst, unicameral cyst, idiopathic bone cavity and progressive bone cyst or cavity. There are few clinical features within the jaws, and the diagnosis is made mainly from radiographical findings. The most frequently affected sites are the region between inferior canines and third molars, and secondly in the mandibular symphysis. SBC of the condyle are rare, and there are approximately 15 cases in the current literature. Treatment of the case will be described, and a literature review of the disease and its management will be presented.

  18. Quistes y fístulas del conducto tirogloso: Nuestra experiencia

    Directory of Open Access Journals (Sweden)

    Manuel Estrada Sarmiento

    1996-12-01

    Full Text Available Se realiza una investigación observacional, retrospectiva y descriptiva de 65 pacientes con diagnóstico clínico e histológico de quistes y/o fístula del conducto tirogloso, con el objetivo de conocer su comportamiento en nuestro medio durante el período 1963-1993. De los 65 pacientes 43 eran masculinos (66,1 % y 22 femeninos. El 20 % con una edad inferior a los 10 años. Nueve pacientes (13,8 % tenían antecedentes de cirugía previa. Se manifestaron como una tumoración cervical en 54 pacientes y en 6 como una fístula. La técnica quirúrgica de Sistrunk se empleó en 62 pacientes (95,4 % en los restantes la exéresis simple del quiste. La mortalidad operatoria fue nula. Tres pacientes (4,6 % presentaron sepsis de la herida. El seguimiento mínimo de los pacientes fue de un año. Dos pacientes mostraron recidivas y fueron reintervenidos a los 10 meses. Esta entidad es relativamente frecuente con predominio en las primeras décadas de la vida. Una terapéutica adecuada conlleva a la resolución de ésta con mortalidad nulaA observational retrospective, and descriptive investigation of 65 patients with clinical and histology-cal diagnosis of cysts and/or fistulas of the thyroglossal duct was carried out to know their behaviour in our enviroment during the period 1983-1993. 43 of the 65 patients were males (66,1 % and 22 females. 20 % of them were under 10 years old. Nine patients (13,8 % had undergone surgery before. Cervical tumour was found in 54 patients and fistula in 6. The Sistrunk's surgical technique was used in 62 patients (95,4 %, where as in the rest it was used the simple exeresis of the cyst. Operative mortality was null. Three patients (4,6 % presented incision sepsis. The minimun follow-up lasted one year. Two patients relapsed and were operated on again 10 months later. This affection is relatively frequent with predominance in the first decades of life. An adequate therapeutics leads to the resolution of it with no mortality

  19. Quistes y fístulas del conducto tirogloso: Nuestra experiencia

    Scientific Electronic Library Online (English)

    Manuel, Estrada Sarmiento.

    1996-12-01

    Full Text Available Se realiza una investigación observacional, retrospectiva y descriptiva de 65 pacientes con diagnóstico clínico e histológico de quistes y/o fístula del conducto tirogloso, con el objetivo de conocer su comportamiento en nuestro medio durante el período 1963-1993. De los 65 pacientes 43 eran masculi [...] nos (66,1 %) y 22 femeninos. El 20 % con una edad inferior a los 10 años. Nueve pacientes (13,8 %) tenían antecedentes de cirugía previa. Se manifestaron como una tumoración cervical en 54 pacientes y en 6 como una fístula. La técnica quirúrgica de Sistrunk se empleó en 62 pacientes (95,4 %) en los restantes la exéresis simple del quiste. La mortalidad operatoria fue nula. Tres pacientes (4,6 %) presentaron sepsis de la herida. El seguimiento mínimo de los pacientes fue de un año. Dos pacientes mostraron recidivas y fueron reintervenidos a los 10 meses. Esta entidad es relativamente frecuente con predominio en las primeras décadas de la vida. Una terapéutica adecuada conlleva a la resolución de ésta con mortalidad nula Abstract in english A observational retrospective, and descriptive investigation of 65 patients with clinical and histology-cal diagnosis of cysts and/or fistulas of the thyroglossal duct was carried out to know their behaviour in our enviroment during the period 1983-1993. 43 of the 65 patients were males (66,1 %) and [...] 22 females. 20 % of them were under 10 years old. Nine patients (13,8 %) had undergone surgery before. Cervical tumour was found in 54 patients and fistula in 6. The Sistrunk's surgical technique was used in 62 patients (95,4 %), where as in the rest it was used the simple exeresis of the cyst. Operative mortality was null. Three patients (4,6 %) presented incision sepsis. The minimun follow-up lasted one year. Two patients relapsed and were operated on again 10 months later. This affection is relatively frequent with predominance in the first decades of life. An adequate therapeutics leads to the resolution of it with no mortality

  20. Genetics Home Reference: 46,XX testicular disorder of sex development

    Science.gov (United States)

    ... disorder catalog Conditions > 46,XX testicular disorder of sex development On this page: Description Genetic changes Inheritance ... 2008 What is 46,XX testicular disorder of sex development? 46,XX testicular disorder of sex development ...

  1. Hematospermia y quiste del conducto mülleriano / Hematospermia and mullerian duct cyst

    Scientific Electronic Library Online (English)

    Nuria, Rodríguez García; Inmaculada, Fernández González; Carlos, Pascual Mateo; Gino, Espinales Castro; Ana Mª, García Tello; Antonio, Berenguer Sánchez.

    2005-12-01

    Full Text Available OBJETIVO: presentación de un caso de quiste de utrículo tratado endoscópicamente. MÉTODO: describimos el caso de un varón de mediana edad que consulta por hematospermia monosintomática de larga evolución. Al tacto rectal presentaba una próstata adenomatosa no sospechosa. Se practicó ecografía transr [...] ectal que revela quiste de utrículo complicado. RESULTADOS: Se realizó marsupialización endoscópica del quiste, consiguiendo remisión total de la hematospermia. CONCLUSIONES: Se debe realizar ecografía transrectal a todos los pacientes que consultan por hematospermia de larga evolución, indicando la marsupialización endoscópica del quiste del conducto mülleriano en aquellos pacientes sintomáticos y con quistes complejos observados en la exploración ecográfica, obteniendo un importante porcentaje de cura o mejoría en este grupo de pacientes sin inducir ningún efecto colateral secundario. Abstract in english OBJECTIVES: To report one case of utriculum cyst treated endoscopically. METHODS: We describe the case of a mid-age male patient consulting for long-term monosymptomatic hemospermia. Rectal digital examination revealed a non suspicious adenomatous prostate. Transrectal ultrasound showed a complicate [...] d utriculum cyst. RESULTS: Endoscopical marsupialization of the cyst was performed with complete remission of hemospermia. CONCLUSIONS: Transrectal ultrasound should be performed in all patients presenting with long-term hemospermia. Endoscopical marsupialization of the mullerian duct cyst is indicated in symptomatic patients or those with complex cysts on ultrasound, offering a high cure/improvement rate in this group of patients without secondary effects.

  2. Quiste broncogénico cervical: Reporte de un caso Cervical bronchogenic cyst: Report of one case

    Directory of Open Access Journals (Sweden)

    JUAN ANTONIO PÉREZ P

    2008-02-01

    Full Text Available Los quistes broncogénicos son malformaciones congénitas del árbol traqueobronquial que se ubican preferentemente en pulmones y mediastino, siendo excepcional su aparición en el cuello. Esta situación conlleva que ante una masa cervical de esta naturaleza se postulen diferentes diagnósticos clínicos de lesiones cervicales que son más corrientes, tales como quiste tiroideo, tirogloso, branquial y tímico, entre otros. La imagenología informa sobre el carácter quístico de la lesión pero no proporciona hallazgos específicos. Durante la intervención quirúrgica tampoco es posible establecer el diagnóstico, puesto que la masa simula los quistes cervicales congénitos más frecuentes. El diagnóstico definitivo se establece mediante la biopsia al constatar en la pared del quiste epitelio respiratorio. Comunicamos el caso de una mujer que presentó un quiste broncogénico de ubicación cervical y discutimos algunos aspectos de esta interesante condiciónBronchogenic cysts are congenital malformations of the tracheobronchial tree that are mainly located in the lungs and mediastinum. Occasionally, they can appear in the neck, generating a cervical mass. Pathology gives the definitive diagnosis. We report a 19 years old female that consulted for an asymptomatic central cervical mass. On examination, a 4 cm diameter painless suprasternal nodule was palpated. Cervical ultrasound and CAT scan showed a cystic lesion. The cyst was completely excised surgically and the pathological report disclosed a bronchogenic cyst

  3. Quiste broncogénico cervical: Reporte de un caso / Cervical bronchogenic cyst: Report of one case

    Scientific Electronic Library Online (English)

    JUAN ANTONIO, PÉREZ P; MAURICIO, GABRIELLI N; ORLANDO, FELMER E; CRISTIÁN, CARRASCO L.

    2008-02-01

    Full Text Available Los quistes broncogénicos son malformaciones congénitas del árbol traqueobronquial que se ubican preferentemente en pulmones y mediastino, siendo excepcional su aparición en el cuello. Esta situación conlleva que ante una masa cervical de esta naturaleza se postulen diferentes diagnósticos clínicos [...] de lesiones cervicales que son más corrientes, tales como quiste tiroideo, tirogloso, branquial y tímico, entre otros. La imagenología informa sobre el carácter quístico de la lesión pero no proporciona hallazgos específicos. Durante la intervención quirúrgica tampoco es posible establecer el diagnóstico, puesto que la masa simula los quistes cervicales congénitos más frecuentes. El diagnóstico definitivo se establece mediante la biopsia al constatar en la pared del quiste epitelio respiratorio. Comunicamos el caso de una mujer que presentó un quiste broncogénico de ubicación cervical y discutimos algunos aspectos de esta interesante condición Abstract in english Bronchogenic cysts are congenital malformations of the tracheobronchial tree that are mainly located in the lungs and mediastinum. Occasionally, they can appear in the neck, generating a cervical mass. Pathology gives the definitive diagnosis. We report a 19 years old female that consulted for an as [...] ymptomatic central cervical mass. On examination, a 4 cm diameter painless suprasternal nodule was palpated. Cervical ultrasound and CAT scan showed a cystic lesion. The cyst was completely excised surgically and the pathological report disclosed a bronchogenic cyst

  4. Testicular size in young adult Sinhalese.

    Science.gov (United States)

    Wikramanayake, E

    1995-06-01

    Height, body weight, arm span and testicular size were measured in 200 Sinhalese men aged 21-31 years. The mean +/- SD right testicular size was 17.2 + 4.1 ml and that of the left was 16.1 + 3.9 ml. The testes were of equal size in 75% and the right testis was larger in 20% of the men. The prevalence of undescended testes was 2%. There as a significant correlation of testicular size with weight (p < 0.05) and a significant correlation of right testicular size with span (p < 0.01). Testicular size was not correlated with height or body mass index. Although the Sinhalese are ethnically closer to the Caucasians, their testicular size is similar to that reported by previously for Thai men. PMID:7558385

  5. QUISTE PARAOVARICO COMPLICADO: CAUSA RARA DE DOLOR ABDOMINAL

    Directory of Open Access Journals (Sweden)

    Ester Ureta H

    2007-01-01

    Full Text Available Se presentan los hallazgos ultrasonográficos y laparoscópicos en un caso de quiste paraovárico torcido correspondiente a una hidátide de Morgagni sin compromiso de la trompa ni del ovario. La paciente de 11 años consultó, al servicio de urgencia por un dolor abdominal agudo que hizo plantear clínicamente la existencia de una apendicitis aguda. La identificación de un apéndice y ovarios normales, junto al hallazgo de una estructura quística compleja próxima al ovario llevaron a la cirugía laparoscópica que identificó la hidátide torcida a derecha y una estructura quística similar no torcida a izquierda. Se discute esta patología como una eventual y rara causa de dolor abdominal agudo en el sexo femenino: We report the ultrasonographic and laparoscopic findings in a case of twisted parovarian cyst related with a Morgagni hydatid, without involving of the tube and ovary. The 11 years old patient consulted for an acute abdominal pain that made suspect the clinical existence of acute appendicitis. The identification of normal appendix and ovaries, and the finding of a complex cyst structure close to the ovary, led to the laparoscopic surgery, that identified a twisted hydatid at the right side and a non twisted cystic structure at the left side. We discuss this pathology as an eventual and rare cause of acute abdominal pain in females

  6. Quiste hidatídico hepático a propósito de un caso

    Scientific Electronic Library Online (English)

    Clavo, María Luisa; Lloeznaly, Ochoa; Julio, Vargas; Belkisyolé, de Noya; Carmen, Zuramay.

    2007-09-01

    Full Text Available Se reporta el caso de paciente femenina de 51 años, con antecedente de contacto con animales domésticos, a la cual se le realizó diagnóstico de quiste hidatídico hepático, en base a estudios de imagen y paraclínicos compatibles por patrón ecográfico, con gran Lesión de Ocupación de Espacio (LOE) quí [...] stica, multivesicular, de aspecto septado, en lóbulo hepático derecho, eosinofilia moderada y discreta elevación del perfil bioquímico hepático, con Elisa (IgG) para hidatidosis positivo, que manifestó buena respuesta a terapia farmacológica única con benzimidazoles (Albendazol) vía oral, con disminución progresiva de la lesión hasta su total desaparición, sin requerir tratamiento quirúrgico, en seguimiento actual de 13 meses. Se revisa la literatura de la enfermedad y manejo terapéutico de la misma. Abstract in english We report the case of a 51 years old female patient, with a history of contact with domestic animals, to whom we diagnosed a Hepatic Hydatid Cyst, on the grounds of image studies and laboratory tests compatible with a spaceoccupying lesion, multivesicular cysts, in the right hepatic lobe; moderate e [...] osinophilia, and a discreet elevation of the hepatic biochemical profile, with Elisa (IgG) positive for Hydatid Cyst disease. She showed a good response to single therapy with benzimidazole (Albendazole), given orally, with a progressive diminution of the lesion until its total disappearance, without requiring surgical treatment, at follow up for 13 months. We review the literature relative to this disease and its therapeutic options.

  7. Quiste de Baker en el curso de la artritis reumatoidea

    Directory of Open Access Journals (Sweden)

    José Pedro Martínez Larrarte

    2000-03-01

    Full Text Available Se presentó un caso con diagnóstico de artritis reumatoidea seropositiva, de un año de evolución, que llevó tratamiento con aines y metotrexate, a pesar de lo cual, mantuvo actividad inflamatoria articular en el nivel de carpos y rodillas, que desarrolló un aumento de volumen de la región posterior de ambas piernas, con dolor espontáneo y signo de Homans positivo. Se valoró la posibilidad inicial de una tromboflebitis de la región poplítea y se llegó a la conclusión que se trataba de un quiste de Baker.A case with diagnosis of seropostive rheumatoid arthritis and a year of evolution was presented. The patients was treated with non-steroidal anti-inflammatories and methotrexate. In spite of this, the inflammatory articular activity was maintained at the level of the carpus and knees and there was a volume increase in the posterior region of both legs, with spontaneous pain and positive Homan´s sign. At first, it was evaluated the possibility of a thrombophlebitis of the popliteal region, but, finally, it was considered as a Baker´s cyst.

  8. Estrogen regulation of testicular function

    OpenAIRE

    Akingbemi Benson T

    2005-01-01

    Abstract Evidence supporting a role for estrogen in male reproductive tract development and function has been collected from rodents and humans. These studies fall into three categories: i) localization of aromatase and the target protein for estrogen (ER-alpha and ER-beta) in tissues of the reproductive tract; ii) analysis of testicular phenotypes in transgenic mice deficient in aromatase, ER-alpha and/or ER-beta gene; and, iii) investigation of the effects of environmental chemicals on male...

  9. Epidermoid carcinoma of the skin mimicking breast cancer / Carcinoma epidermoide na pele da mama simulando câncer de mama

    Scientific Electronic Library Online (English)

    Baltasar, Melo Neto; Giuliano da Paz, Oliveira; Sabas Carlos, Vieira; Livio Rodrigues, Leal; José Andrade de Carvalho, Melo Junior; Cyro Franklin, Vieira.

    2013-04-01

    Full Text Available O câncer de pele não-melanoma é o câncer mais frequente no mundo. O carcinoma espinocelular ocorre mais frequentemente em áreas expostas ao sol como cabeça e pescoço. Quando o carcinoma espinocelular se desenvolve na região da mama, ulcerando e invadindo o tecido glandular, pode simular um câncer de [...] mama. A confirmação histopatológica, aliada à história clínica, é ferramenta importante para o diagnóstico correto. Apresentamos um caso de carcinoma epidermóide da pele da mama diagnosticado inicialmente como câncer de mama. Abstract in english Nonmelanoma skin cancer is the most frequent cancer in the world. Squamous cell cancer often occurs in sun-exposed areas, such as the head and neck. When it involves the breast and ulce-rates, invading the glandular parenchyma, it may mimic breast cancer. Confirmation by means of histopathological e [...] xamination, combined with clinical examination, is a critical instrument for the accuracy of the diagnosis. We report a case of an epidermoid carcinoma located on the breast skin, initially diagnosed as breast cancer.

  10. Tumores testiculares en la infancia / Testicular Tumours in Infancy and children

    Scientific Electronic Library Online (English)

    A., Bujons; J., Caffaratti; M., Pascual; O., Angerri; J.M., Garat; H., Villavicencio.

    2011-02-01

    Full Text Available Introducción: los tumores testiculares prepuberales son distintos a los que se presentan en la edad adulta. Tradicionalmente han sido considerados malignos, pero realmente los tumores testiculares benignos son más frecuentes en esta edad. Material y métodos: revisamos nuestra experiencia en el trata [...] miento de los tumores testiculares en niños Abstract in english Introduction: prepubertal testicular tumours are different from those that appear during adulthood. Traditionally, they were considered to be malignant, however benign testicular tumours are actually more frequent at this age. Materials and methods: we analysed our experience in the treatment of tes [...] ticular tumours in children

  11. Current Clinical Applications of Testicular Cancer Biomarkers.

    Science.gov (United States)

    Mir, Maria C; Pavan, Nicola; Gonzalgo, Mark L

    2016-02-01

    Current use of testicular biomarkers for screening, diagnosis, and follow-up is reviewed in the context of potential clinical utility of these tests. This information will be of value to clinicians to determine patient suitability for certain treatments and will also assist in reviewing current literature regarding potential biomarkers that may be used for testicular cancer. PMID:26614034

  12. Sarcoidose testicular: um diagnóstico a ser considerado

    Directory of Open Access Journals (Sweden)

    Vanderlei Real

    2011-04-01

    Full Text Available Sarcoidosis is a disease of unknown etiology, characterized by the presence of noncaseating granulomas in multiple organs. We present a case of testicular sarcoidosis in a white, 55-year-old man who has come to our department complaining of bilateral testicular discomfort and weight loss.

  13. Tumor canceroso testicular: Seminoma clásico / Testicular Cancer Tumor: Classic Seminoma

    Scientific Electronic Library Online (English)

    Paola Danitza, Luizaga Velasco; Luis Antonio, Luizaga Velasco; Boris, Mejia Arce; Sandra, Campuzano J..

    Full Text Available El tumor canceroso tipo seminoma es el cáncer testicular más frecuente, afecta con mayor frecuencia a las personas de una edad media de 50 años. El seminoma presenta factores de riesgo como criptorquidia, infertilidad y antecedentes familiares de primer grado con cáncer. La estadificación determina [...] la extensión de la invasión hacia órganos vecinos; TNM (Tumor, Nódulo, Metástasis). El diagnóstico se realiza por la clínica, se observa una masa creciente de gran volumen, pero también se usa Marcadores Tumorales; como la Alfa feto proteína, la cual es negativa siempre para seminoma y B Gonadotrofina Coriónica Humana, la cual con muy poca frecuencia está elevada. Entre los métodos de imagen que se usan están la Radiografía de tórax, Tomografía de abdomen y pelvis para descartar metástasis. Se presenta un caso de un paciente de 52 años de edad, con una masa voluminosa testicular- indolora, de unos 7 años de evolución que desde hace 2 meses presenta puntos de hemorragia externa. Al examen físico presenta una masa de 18 por 15 cm, con un punto de hemorragia en la región escrotal y secreción purulenta en el prepucio, posteriormente se procede al tratamiento adecuado. Abstract in english The cancerous tumor type seminoma is the most common testicular cancer, most frequently affects people of an average age of 50 years. The seminoma presents risk factors such as cryptorchidism, infertility, and a family history of first grade with cancer. Staging determines the extent of invasion int [...] o neighbouring organs; TNM (Tumor, nodule, Metastasis). The diagnosis is carried out by the clinic there is a growing mass of high-volume, but also used tumoral markers; as the alpha protein, which is always negative to seminoma and fetal Human B Chorionic Gonadotropin, which rarely is elevated. The methods of image that are used include chest radiograph and tomography of abdomen and pelvis to rule out metastasis. A case of a patient's 52 years of age, with a bulky mass testicular - painless, about 7 years of evolution from 2 months ago has points of external bleeding. A physical exam presents a mass of 18 by 15 cm, with a point of hemorrhage in the scrotal region and purulent secretion in the foreskin, and then proceeds to the appropriate treatment.

  14. QUISTES RETRO-AREOLARES EN ADOLESCENTES: ASPECTOS CLÍNICOS Y ULTRASONOGRAFICOS

    Scientific Electronic Library Online (English)

    Eleonora, Horvath; Miguel Angel, Pinochet V; Andrea, Huneeus V; Marcela, Uchida S; María Cecilia, Galleguillos P; Paulina, González M; Heriberto, Wenzel K; Eduardo, Soto; Chyla, Ríos C; María Paz, Duran C; Gina, Baldassare P; Jocelyn, Gálvez T.

    Full Text Available Los quistes retroareolares son frecuentes en niñas pre y postmenárquicas. Raramente se diagnostican en el varón. Corresponden a dilataciones quísticas de glándulas mamarias accesorias que se abren junto con una glándula sebácea en la areola, pueden ser únicos o múltiples, uni o bilaterales, palpable [...] s o hallazgos incidentales en ecografía. Los no complicados tienen morfología variable, paredes delgadas y contenido anecogénico, pudiendo observarse sedimento calcico en su lumen. Los complicados presentan paredes engrosadas, hipervascularizadas, con contenido ecogénico, avascular, tejidos adyacentes hiperecogénicos y aumento de la vascularización al Doppler color. Sin tratamiento, pueden transformarse en abscesos retroareolares. La complicación inflamatoria se trata con antiinflamatorios y/o antibióticos. No requieren biopsia diagnóstica ni punción evacuadora, puesto que se drenan espontáneamente a la areola. El conocimiento del cuadro clínico y su aspecto ul-trasonográfico permitirá orientar adecuadamente a los pacientes y sus familias Abstract in english Retroareolar cysts are common in pre and postmenarchic girls. Boys are rarely diagnosed with this condition. They correspond to cystic dilatations of the accessory mammary glands that open along with a sebaceous gland at the areola and can be single or multiple, uni or bilateral, palpable or inciden [...] tal findings on ultrasound. They have variable morphology, thin walls, anechogenic content, sometimes calcic sediment can be observed in their lumen. Infected cysts present enlarged, hypervascularized walls; their content is echogenic, avascular and the adjacent tissue is hyperechogenic, with increased vascularization at color Doppler. If not treated, may become retroareolar abscesses. Inflamatory complications are treated with anti-inflamatory drugs and/or antibiotics. No diagnostic biopsy or puncture aspiration is required, since they are spontaneously drained at the areola. In order to appropriately advise patients and families, it is necessary to have knowledge of both the medical and the ultrasonographic aspects of them and their complications

  15. Testicular Cancer, Version 2.2015.

    Science.gov (United States)

    Motzer, Robert J; Jonasch, Eric; Agarwal, Neeraj; Beard, Clair; Bhayani, Sam; Bolger, Graeme B; Chang, Sam S; Choueiri, Toni K; Costello, Brian A; Derweesh, Ithaar H; Gupta, Shilpa; Hancock, Steven L; Kim, Jenny J; Kuzel, Timothy M; Lam, Elaine T; Lau, Clayton; Levine, Ellis G; Lin, Daniel W; Michaelson, M Dror; Olencki, Thomas; Pili, Roberto; Plimack, Elizabeth R; Rampersaud, Edward N; Redman, Bruce G; Ryan, Charles J; Sheinfeld, Joel; Shuch, Brian; Sircar, Kanishka; Somer, Brad; Wilder, Richard B; Dwyer, Mary; Kumar, Rashmi

    2015-06-01

    Germ cell tumors (GCTs) account for 95% of testicular cancers. Testicular GCTs constitute the most common solid tumor in men between the ages of 20 and 34 years, and the incidence of testicular GCTs has been increasing in the past 2 decades. Testicular GCTs are classified into 2 broad groups--pure seminoma and nonseminoma--which are treated differently. Pure seminomas, unlike nonseminomas, are more likely to be localized to the testis at presentation. Nonseminoma is the more clinically aggressive tumor associated with elevated serum concentrations of alphafetoprotein (AFP). The diagnosis of a seminoma is restricted to pure seminoma histology and a normal serum concentration of AFP. When both seminoma and elements of a nonseminoma are present, management follows that for a nonseminoma. The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Testicular Cancer outline the diagnosis, workup, risk assessment, treatment, and follow-up schedules for patients with both pure seminoma and nonseminoma. PMID:26085393

  16. Familial testicular cancer and developmental anomalies

    International Nuclear Information System (INIS)

    Familial occurrence belongs to factors followed in etiology and pathogenesis of testicular germ-cell tumors. Association with abnormal testicular development, or with other risk factors is relatively frequent. In our material 650 patients had been treated for testicular cancer in the period of 1981-1995. Familial occurrence was observed 7-times (1.08), most frequently in combination with cryptorchidism. Individual families were analyzed in details, including HLA typing. On basis of the observations the supplementation of initial examination of each patient with suspicious testicular cancer with detailed familiar history aimed also at the occurrence of urogenital developmental anomalies and tumors has been recommended. The knowledge about familial tumor occurrence in the first-degree relatives in combination with thorough testicular self-examination is being considered of great importance in the secondary prevention. (author)

  17. Testicular irradiation in childhood lymphoblastic leukaemia

    International Nuclear Information System (INIS)

    The effect of randomly allocated testicular irradiation on the subsequent incidence of testicular infiltration and disease-free survival was assessed in two Medical Research Council Childhood Leukaemia trials, UKALL VI and UKALL VII. None of the 83 boys who actually received testicular radiotherapy subsequently developed gonadal disease, whereas 18 of the 163 who were not irradiated did. Despite this there is no apparent difference in disease-free survival for those randomized to receive testicular irradiation compared to those who were not, after a minimum of 8 years follow up. Although prophylactic testicular irradiation appears to prevent subsequent gonadal relapse there is no evidence that it improves overall prognosis when adequate systemic chemotherapy is used. As it has considerable long-term side effects it cannot be recommended as routine therapy. (author)

  18. Ultrassonografia testicular em caprinos jovens da raça Alpina / Testicular ultrasonography in young Alpine goats

    Scientific Electronic Library Online (English)

    L.R.B., Carazo; J.D., Guimarães; T.P., Machado; T.P.L.C., Machado; F.A.S.A.M., Oliveira; D.B., Pereira.

    2014-04-01

    Full Text Available Objetivou-se com este trabalho observar as mudanças do parênquima testicular de acordo com o fotoperíodo e com a faixa etária dos animais por meio da ecotextura testicular e a viabilidade do uso do ultrassom na avaliação testicular. Foram utilizados 4 animais desde o 6° até o 13° mês de idade. Os ex [...] ames ecográficos foram realizados a cada 15 dias para avaliar a ecotextura testicular. O parênquima testicular mostrou-se moderadamente ecogênico e homogêneo. Foi observado comportamento semelhante na ecotextura testicular durante o período de avaliação, sendo maior no 8º mês de idade, quando o volume testicular também foi maior; tais mudanças foram relacionadas com o fotoperíodo da região. A avaliação ultrassonográfica dos testículos mostrou-se um método eficiente, capaz de detectar as mudanças no parênquima testicular ao longo do tempo, e como ferramenta alternativa para diferenciação de condições normais e patológicas em caprinos. Abstract in english The purpose of this study was to observe changes in the testicular parenchyma of male goats. Changes were observed in terms of goat age, evaluating the echotexture and ultrasound viability in the testicles. Four animals were used, ranging from six to 13 months of age. The echographic examinations we [...] re performed every 15 days to assess echotexture of the testicle. The testicular parenchyma appeared moderately echogenic and homogeneous. Similar results were observed in testicular echotexture during the evaluation period. The highest results appearing during the eighth month of age, when the testicular volume was also highest; such changes were related to the regional photoperiod. The ultrasound evaluation of the testicles was shown to be an effective method, ultimately capable of detecting changes in testicular parenchyma over time, being an alternative to differentiation normal and pathological conditions in goats.

  19. Quiste mesentérico: experiencia en 4 casos / Mesenteric cyst: experience in 4 cases

    Scientific Electronic Library Online (English)

    David, Martínez-Ramos; Carlos, Rodríguez-Pereira; Javier, Escrig-Sos; Pellicer Castell, Vicente; Juan Manuel, Miralles-Tena; José Luis, Salvador-Sanchís.

    2005-12-01

    Full Text Available El quiste mesentérico es una enfermedad poco frecuente, cuya importancia ha sido menospreciada en demasiadas ocasiones en la literatura médica. La baja incidencia de la enfermedad y la creencia errónea de que se trata de un proceso benigno y asintomático han contribuido al escaso interés por su cono [...] cimiento. Se realizó un estudio retrospectivo con revisión de los pacientes ingresados en el Servicio de Cirugía General y Digestiva del Hospital General de Castellón entre enero de 1990 y noviembre de 2005. Se diagnosticaron 4 quistes mesentéricos de los 34 355 ingresos en nuestro servicio. La mitad eran mujeres y la media de edad fue de 25 años. Tres casos presentaron síntomas y sólo uno fue un hallazgo casual. La manifestación clínica más frecuente fue el dolor abdominal leve y difuso. Uno de los pacientes se complicó con una perforación espontánea del quiste y peritonitis. El tratamiento fue la exéresis quirúrgica en todos los casos. Las vías de abordaje fueron: 3 laparotomías y 1 laparoscopia. Únicamente un caso requirió resección intestinal por déficit en la vascularización. No hubo ninguna recidiva tras la cirugía. A pesar de la baja frecuencia de esta enfermedad, su conocimiento es necesario ya que se pueden presentar síntomas cuando el quiste ha crecido, así como complicaciones graves (hemorragia, perforación, obstrucción intestinal, malignización, etc.), que se pueden prevenir con la intervención quirúrgica, incluso en los casos asintomáticos

  20. QUISTE DE INCLUSIÓN EPIDÉRMICO VULVAR COMO COMPLICACIÓN TARDÍA DE CIRCUNCISIÓN RITUAL

    Directory of Open Access Journals (Sweden)

    Jorge Andrés Robert S

    2010-01-01

    Full Text Available Presentamos un caso de quiste de inclusión epidérmico, como complicación tardía, en una mujer africana con antecedente de mutilación genital tipo II o clitoridectomía total, durante su infancia.We report a case of epidermal inclusion cyst as a late complication in an African woman with history of ritual genital mutilation type II or total excision during childhood.

  1. QUISTE DE INCLUSIÓN EPIDÉRMICO VULVAR COMO COMPLICACIÓN TARDÍA DE CIRCUNCISIÓN RITUAL

    Scientific Electronic Library Online (English)

    Jorge Andrés, Robert S; Roberto, Yazigi I; Paolo, Ricci A; Antonio, Piottante B.

    Full Text Available Presentamos un caso de quiste de inclusión epidérmico, como complicación tardía, en una mujer africana con antecedente de mutilación genital tipo II o clitoridectomía total, durante su infancia. [...] Abstract in english We report a case of epidermal inclusion cyst as a late complication in an African woman with history of ritual genital mutilation type II or total excision during childhood. [...

  2. Quiste gigante de la glándula de Bartolino: reporte de caso y revisión de la literatura

    Directory of Open Access Journals (Sweden)

    Édgar E Rivas-Perdomo

    2010-12-01

    Full Text Available Introducción: en el presente artículo se expone el caso de una paciente que tuvo un quiste gigante de la glándula de Bartolino, el cual alcanzó un diámetro de 10 cm. La paciente presentó algunas dificultades diagnósticas y terapéuticas por lo que fue necesaria la escisión de la glándula y la posterior reconstrucción de la vulva. El diagnóstico definitivo fue establecido por anatomía patológica. El caso se presenta con el objetivo de realizar una revisión de la literatura respecto al tratamiento. Materiales y métodos: se realizó una búsqueda de la literatura relacionada con el tema en las bases de datos electrónicas PubMed, SciELO, ScienceDirect y MD Consult, utilizando las palabras clave: "glándulas de Bartolino", "quistes" y "marsupialización". Además, se revisaron referencias de libros de textos. Conclusiones: la urgencia en el tratamiento depende de los síntomas de la paciente. Un quiste asintomático podría no requerir tratamiento. Sin embargo, la no mejoría dentro de las primeras 72 horas o la evolución hacia una forma de absceso requerirá un tratamiento quirúrgico de emergencia. Se ha descrito una amplia variedad de tratamientos que incluyen una serie de procedimientos quirúrgicos tales como: 1 incisión simple y drenaje, 2 fistulización o marsupialización, 3 colocación de un catéter de Word, 4 escleroterapia con alcohol, 5 aplicación de nitrato de plata y 6 ablación del quiste utilizando dióxido de carbono (CO2 con láser.

  3. Enucleación de quiste periapical simultáneo a la obturación del sistema de conductos radiculares

    Directory of Open Access Journals (Sweden)

    Lida Velazque

    2014-06-01

    Full Text Available Introducción: los quistes periapicales representan el tipo más frecuente dentro de los quistes odontogénicos. Su origen está relacionado con una necrosis pulpar y un consecuente estímulo de los restos epiteliales del ligamento periodontal (Malassez. Objetivo: describir un caso clínico de enucleación de quiste periapical simultáneo a la obturación del sistema de conductos radiculares. Presentación del caso: paciente de sexo femenino, 67 años de edad, sin alteraciones sistémicas; buscó atención odontológica por presentar dolor dental y acúmulo de alimentos en la región de molares inferiores del lado izquierdo. Al examen clínico se observó caries extensa en el segundo molar inferior izquierdo con compromiso de furca, ausencia de aumento de volumen vestibular, sin fistula; en la radiografía periapical se evidenció lesión cariosa extensa recidivante en el segundo molar inferior izquierdo, y primer molar inferior izquierdo con tratamiento endodóntico y presencia de área radiolúcida de contornos bien definidos en la región periapical compatible con quiste periapical. El tratamiento estuvo a cargo de un equipo multidisciplinario por lo que se decidió realizar exodoncia del segundo molar inferior izquierdo y cirugía paraendodóntica con enucleación quirúrgica simultánea a la obturación del sistema de conductos radiculares primer molar inferior izquierdo; el examen histopatológico de la muestra extraída comprobó tratarse de un quiste periapical. Se realizó seguimiento radiográfico dos años después y mostró un completo reparo óseo del área afectada. Conclusiones: se concluye que el tratamiento descrito constituye una alternativa válida para la resolución de casos donde la endodoncia convencional es limitada para mantener la función y estética de una pieza dentaria.

  4. Tumor canceroso testicular: Seminoma clásico

    Directory of Open Access Journals (Sweden)

    Campuzano J. Sandra

    2011-06-01

    Full Text Available El tumor canceroso tipo seminoma es el cáncer testicular más frecuente, afecta con mayor frecuencia a las personasde una edad media de 50 años. El seminoma presenta factores de riesgo como criptorquidia, infertilidad y antecedentes familiares de primer grado con cáncer. La estadificación determina la extensión de la invasión hacia órganos vecinos; TNM (Tumor, Nódulo, Metástasis. El diagnóstico se realiza por la clínica, se observa una masa crecientede gran volumen, pero también se usa Marcadores Tumorales; como la Alfa feto proteína, la cual es negativa siempre para seminoma y B Gonadotrofina Coriónica Humana, la cual con muy poca frecuencia está elevada. Entre los métodos de imagen que se usan están la Radiografía de tórax, Tomografía de abdomen y pelvis para descartar metástasis. Se presenta un caso de un paciente de 52 años de edad, con una masa voluminosa testicular- indolora, de unos 7 años de evolución que desde hace 2 meses presenta puntos de hemorragia externa. Al examen físico presenta una masa de 18 por 15 cm, con un punto de hemorragia en la región escrotal y secreción purulenta en el prepucio, posteriormente se procede al tratamiento adecuado.

  5. CISS MR imaging findings of epidermoid tumor : comparison with spin-echo images

    International Nuclear Information System (INIS)

    To evaluate CISS MR imaging findings of epidermoid tumor in comparison with conventional spin-echo images. We studied 6 cases of epidermoid tumor in the subarachnoid space. We used a 1.5T MR unit to obtain CISS images(TR/TE/FA ; 12.3msec/5.9 msec/700) and T1- and T2- weighted spin-echo images. CISS MR imaging findings were evaluated with respect to tumor's signal intensity , contour, and relation with adjacent structures. Conspicuity of the tumor was compared between CISS and spin-echo images. A quantitative analysis was performed by measuring tumor to CSF contrast. In qualitative analysis, three radiologists independently compared CISS image and conventional spin-echo images for visibility of the tumor and graded them into three categories( poor, good, and excellent). Epidermoid tumors were located in the cerebellopontine angle in 4 cases, the prepontine cisstern in 1 case, and the cerebellopontine angle-prepontine cistern in 1 case. The tumors were hyperintense relative to brain parenchyma and hypointense relative to CSF on CISS images, were lobulated, encased adjacent cranial nerve and vessels, and invaginated into brain parenchyma. In qualitative analysis, CISS images showed clear demarcation between tumor and CSF, exact tumor extension, and tumor's relation with cranial nerves and vessels better than conventional spin-echo images. In quantitative analysis, the mean contrast values of tumor to CSF on T1-, T2-weighted images, and CISS images were 0.12, 0.06, and 0.52, respectively. The contrast value for CISS images was significantly higher than that for T1-and T2-weighted images(p<0.05). Epidermoid tumors in the subarachnoid space are better demonstrated on CISS images than on conventional spin-echo images. This special MR sequence can be added as a routine protocol in the diagnosis of subarachnoid epidermoid tumor

  6. Lipid peroxidation in adrenal and testicular microsomes.

    OpenAIRE

    Brogan, W C; Miles, P. R.; Colby, H D

    1981-01-01

    Studies were carried out to determine the actions of and interactions between ascorbate, NADPH, Fe2+, and Fe3+ on lipid peroxidation in adrenal and testicular microsomes. Ascorbate-induced malonaldehyde production was maximal in adrenal and testicular microsomes at an ascorbate concentration of 1 X 10(-4)M. Fe2+, at levels between 10(-6) and 10(-3)M, produced concentration-dependent increases in lipid peroxidation in adrenal and testicular microsomes; Fe2+ had a far greater effect than Fe3+ i...

  7. Testicular cancer: addressing the psychosexual issues.

    LENUS (Irish Health Repository)

    Moore, Annamarie

    2012-01-31

    Testicular cancer is the most common malignancy in men aged 15-35 years and predominantly occurs at a time in a man\\'s life when important decisions about marriage, starting a family and a professional career are being made. While treatments for testicular cancer are very successful, they can have a major impact on the person\\'s sexuality and sense of self. The focus of this article is on exploring the impact of cancer treatments for testicular cancer on men\\'s sexuality and how nurses can respond to their concerns in a sensitive and informed manner.

  8. [Pulmonary sarcoidosis with testicular and epididymal disease].

    Science.gov (United States)

    Calvo Bonachera, J; Sebastián Gil, M D; Bernal Rosique, M S; Calvo Bonachera, M D; Pascual Lledo, F J; Valencia Rodríguez, A

    1999-10-01

    We expose a case of sarcoidosis with pulmonary and intrathoracic ganglion infection added to an infrequent testicular and epididymal affection simultaneously. We only have found this association in six cases in the revised literature, but we didn't found the affection of Morgagni's hydatid by sarcoidosis. The presence of testicular mass and hilar adenopathies in young patients make us to think about a diagnostic threat. The inguinal treatment with testicular biopsy has been chosen like the diagnostic management in this case. PMID:10603671

  9. An unusual presentation of testicular tumor

    International Nuclear Information System (INIS)

    A case of testicular choriocarcinoma is reported in which blood mixed stools and haemoptysis were the presenting manifestations as the patient never told about the testicular swelling to his parents. Orchidectomy was performed but the patient presented again with massive hematemesis due to gastric perforation secondary to gastric metastasis. The size of the testis at diagnosis was approximately 12 x 7cm. This was also unusual as testicular choriocarcinoma presents as a small mass. The patient eventually died of the complications within one month of diagnosis. (author)

  10. Carcinoma broncogénico epidermoide en un hombre de 21 años Epidermoid bronchogenic carcinoma in a 21 year old black man

    Directory of Open Access Journals (Sweden)

    John Jairo Duque Alzate

    1999-01-01

    Full Text Available Hombre de 21 años de edad de raza negra, natural del Chocó (Colombia, quien ha desempeñado diversos oficios; presentó un síndrome de dificultad respiratoria de dos meses de evolución, dolor pleurítico derecho, insuficiencia cardíaca congestiva y síntomas sistémicos. En la necropsia se encontró una masa tumoral blanco-grisácea de 10 x 8 cm, homogénea, con áreas de necrosis, originada en el bronquio principal de los lóbulos inferior y medio derechos y que invadió por vecindad en forma de coraza todo el pericardio causando una pericarditis constrictiva tumoral. El estudio microscópico correspondió a un carcinoma broncogénico tipo epidermoide bien diferenciado. El carcinoma broncogénico se asocia frecuentemente con el consumo de cigarrillo pero su incidencia ha c.umentado entre las personas no fumadoras, lo que sugiere la posibilidad de otros factores que influyen en su presentación como son los contaminantes atmósféricos, la predisposición genética, la dieta deficiente en vitamina A y carotenos, la presencia de ciertos virus y cambios inmunológicos. Este tumor constituye el 16% de todos los cánceres en el hombre y e113% en las mujeres; aparece con mayor frecuencia entre los 40 y los 70 años y sólo del1 al 5% de los casos se presenta en menores de 40 años. A 21 year cid black man, native from Chocó (Colombia, variously employed, who presented with a respiratory difficulty syndrome of two months of evolution, right pleuritic pain, congestive cardiac failure and systemic symptoms. A homogeneic white .grayish tumor measuring 8 by 10 cm with necrotic areas was found at necropsy. The tumor originated in the main bronchial tube of the lower and middle lobes of the right lung and invaded the entire pericardial vicinity forming a cuirass and causing tumoral constrictive pericarditis. Microscopic studies revealed a well differentiated squamous type bronchogenic carcinoma. Bronchogenic carcinomas are frequently associated with cigarette smoking. However, their incidente has increased among non. smokers, suggesting the possibility that there are other causal factors, such as atmospheric contaminants, genetic predisposition, diets deficient in vitamin A and carotene, presente of certain viruses and immunologic changes. Lung cancer constitutes 16% among the types of cancer suffered by men and 13% among women, it has its greatest incidente in groups between 40 and 70 years of age and only 1 to 5 percent of thecasesoccur in groupsunder theageofforty years.

  11. Tumor testicular metacronico secundario a carcinoma vesical infiltrante / Metachronic testicular tumor secondary to invasive bladder carcinoma

    Scientific Electronic Library Online (English)

    Francisco Javier, Vicente Prados; José Luís, Rosales Leal; Beatriz, Honrubia Vilchez; Antonio, Fernández Sánchez; Fernando, Vázquez Alonso; Manrique, Pascual Geler; Antonio, Martínez Morcillo; Francisco, Rodríguez Herrera; Eduardo, Espejo Maldonado; José Manuel, Cozar Olmo; Miguel, Tallada Buñuel.

    2007-02-01

    Full Text Available Objetivo: Presentar un caso raro de metástasis testicular secundaria a carcinoma urotelial infiltrante años después de practicada cirugía radical. Métodos: Exposición del caso clínico: paciente de 71 años sometido a cistoprostatectomía radical con uretrectomía por tumor vesical infiltrante. A los si [...] ete años debuta con dolor y aumento del tamaño testicular derecho. Se le practicó orquiectomía por vía inguinal siendo diagnosticado de metástasis testicular de carcinoma vesical de alto grado. y revisión de la literatura publicada al respecto. Resultados: Supervivencia libre de enfermedad a los 12 meses de la orquiectomía. Conclusiones: El tumor testicular metastático excluyendo leucemias y linfomas es extremadamente raro. La presencia de metástasis testiculares supone una diseminación metastásica a otros niveles y por ello la Quimioterapia podría mejorar el pronóstico. Abstract in english Objective: To report a rare case of testicular metastasis secondary to an infiltrative transitional cell carcinoma years after radical surgery. Methods: Case Report: 71-year-old male patient with history of infiltrative bladder tumor, status post radical cystoprostatectomy with urethrectomy. Seven y [...] ears after surgery he presents with pain and swelling in the right testicle. Inguinal orchyectomy was carried out with the pathologic diagnosis of testicular metastasis of a high-grade transitional cell carcinoma. We perform a bibliographic review. Results: The patient is disease-free twelve months after orchyectomy. Conclusions: Apart from leukemia and lymphoma, testicular metastases are extremely rare. The existence of testicular metastases means a metastatic dissemination to other organs, therefore chemotherapy could improve prognosis.

  12. [The cytological diagnostics of dysplasia and epidermoid carcinoma of the cervix in studying the nucleolar-organizing regions of chromosomes].

    Science.gov (United States)

    Bolgova, L S; Tuganova, T N; Alekseenko, O I

    2012-11-01

    The study of the nucleolar-organizing regions of chromosomes in the cells of dys-plastically modified squamous epithelium and epidermoid cancer of cervix was carried out. The successive increase of quantita-tive content of main morphofunctional types of nucleoli is established including active compact and transient nucleolonemic-compact ones in accordance with in-crease of dysplastic modifications and appearance of signs of epidermoid cancer of cervix. The dominance of percentage content of large argyrophilic granules in nu-cleoli of nucleolonemic type under epidermoid cancer of cervix as compared with dysplasia is established. The algorithm of differentiating cytological diagnostics of the degree of dysplasia and epidermoid cancer of cervix is developed. This algo-rithm reflects the degree of structural functional modifications of nucleolar-organizing regions of chromosomes. PMID:23305016

  13. Testicular myeloid sarcoma: case report

    Directory of Open Access Journals (Sweden)

    Luzia Beatriz Ribeiro Zago

    2013-01-01

    Full Text Available Myeloid sarcomas are extramedullary solid tumors composed of immature granulocytic precursor cells. In association with acute myeloid leukemia and other myeloproliferative disorders, they may arise concurrently with compromised bone marrow related to acute myeloid leukemia, as a relapsed presentation, or occur as the first manifestation. The testicles are considered to be an uncommon site for myeloid sarcomas. No therapeutic strategy has been defined as best but may include chemotherapy, radiotherapy and/or hematopoietic stem cell transplantation. This study reports the evolution of a patient with testicular myeloid sarcoma as the first manifestation of acute myeloid leukemia. The patient initially refused medical treatment and died five months after the clinical condition started.

  14. Testicular myeloid sarcoma: case report

    Scientific Electronic Library Online (English)

    Luzia Beatriz Ribeiro, Zago; Antônio Alexandre Lisbôa, Ladeia; Renata Margarida, Etchebehere; Leonardo Rodrigues de, Oliveira.

    Full Text Available Myeloid sarcomas are extramedullary solid tumors composed of immature granulocytic precursor cells. In association with acute myeloid leukemia and other myeloproliferative disorders, they may arise concurrently with compromised bone marrow related to acute myeloid leukemia, as a relapsed presentatio [...] n, or occur as the first manifestation. The testicles are considered to be an uncommon site for myeloid sarcomas. No therapeutic strategy has been defined as best but may include chemotherapy, radiotherapy and/or hematopoietic stem cell transplantation. This study reports the evolution of a patient with testicular myeloid sarcoma as the first manifestation of acute myeloid leukemia. The patient initially refused medical treatment and died five months after the clinical condition started.

  15. The protective effect of dexpanthenol on testicular atrophy at 60th day following experimental testicular torsion.

    Science.gov (United States)

    Etensel, Barlas; Ozkisacik, Sezen; Ozkara, Esra; Serbest, Ye?im Aksu; Oztan, Onur; Yazici, Mesut; Gürsoy, Harun

    2007-03-01

    Despite the prompt diagnosis and treatment of testicular torsion (TT), there are problems with fertility and atrophy after testicular salvage. Dexpanthenol (Dxp) is the biologically active alcohol of pantothenic acid (PA). Dxp is converted to PA in tissues. PA increases the content of reduced glutathione (GSH), Coenzyme A and ATP synthesis in cells. GSH and glutathione-dependent peroxidases (GPX) are the major defense systems against oxidative stress. GPX-4 is the major antioxidant in testicular tissue. However, the activity of GPX-4 appeared and increased only after puberty. We investigated the effect of Dxp on testicular atrophy after TT at the 60th day. Rats were separated randomly into four groups. Group C: control group, group Td: torsion + detorsion, group Sal: torsion + saline + detorsion, group Dxp: torsion + Dxp + detorsion. The left testis was rotated 720 degrees for 2 h. In group Sal, normal saline and in group Dxp, Dexpanthenol were injected intraperitonally, 30 min before detorsion. After 60 days, the testicular weights and volumes were measured. Histopathology of the left testis was evaluated with mean seminiferous tubular diameter (MSTD) and mean testicular biopsy score (MTBS). The left (torsed) testicular weight and volume of groups Td and Sal were significantly lower compared to group Dxp. The MSTD and MTBS of group Td and Sal were significantly lower than group Dxp. Contralateral testicular weight and volume of groups Td, Sal and Dxp had no significant difference compared to the control group. Dxp significantly prevented testicular atrophy after 60 days of TT. Dxp has FDA approval, is safe, cost effective and readily available. Its relevance for clinical trials may especially be for the problem of testicular atrophy catastrophe, seen very frequently following testicular salvage. PMID:17205291

  16. Occupational Causes of Testicular Cancer in Adults

    OpenAIRE

    L Fritschi; Hense, S; Dreger, S; Behrens, T.; B Mester

    2010-01-01

    Testicular cancer is one of the commonest cancers in men of working age, and is increasing in incidence in Europe and North America. One suggested mechanism of causation is that there is impaired differentiation of germ cells in the pre- or perinatal period, followed by malignant transformation in later life, possibly by a hormonal mechanism. Endocrine disrupting chemicals (EDCs) have been a major focus of interest for etiological research into testicular cancer because they interact with var...

  17. Baldness, acne and testicular germ cell tumors

    OpenAIRE

    Trabert, Britton; Sigurdson, Alice J.; Sweeney, Anne M.; Amato, Robert J.; Strom, Sara S.; McGlynn, Katherine A

    2010-01-01

    Androgen levels during critical periods of testicular development may be involved in the etiology of testicular germ cell tumors (TGCT). We evaluated the roles of adolescent and early adult life correlates of androgen exposure and TGCT in a hospital-based case control study. TGCT cases (n=187) and controls (n=148), matched on age, race and state of residence, participated in the study. Unconditional logistic regression was used to estimate associations between TGCT and male pattern baldness, ...

  18. Occupational Causes of Testicular Cancer in Adults

    Directory of Open Access Journals (Sweden)

    L Fritschi

    2010-09-01

    Full Text Available Testicular cancer is one of the commonest cancers in men of working age, and is increasing in incidence in Europe and North America. One suggested mechanism of causation is that there is impaired differentiation of germ cells in the pre- or perinatal period, followed by malignant transformation in later life, possibly by a hormonal mechanism. Endocrine disrupting chemicals (EDCs have been a major focus of interest for etiological research into testicular cancer because they interact with various hormonal pathways. Several EDCs including bisphenol A, phthalates, metals, polychlorinated biphenyls, and organochlorines have been investigated, but there are few studies and those that exist have not been able to assess exposure well. In addition, several studies, particularly those with better exposure assessment, have suggested that workers in electrical occupations have increased risks of testicular cancer. Electromagnetic radiation may have subthermal effects or may disrupt hormone release. Chronodisruption such as due to shift-work could potentially increase the risk of testicular cancer via disruption of hormonal cycles, but only one study has so far investigated this possibility. Lastly, solvent exposure, particularly to dimethylformamide, has been suggested to be associated with testicular cancer, but almost all these studies are based on job title only, with no specific assessment of solvent exposure. In conclusion, there is little evidence available on which to base definitive statements about occupational causes of testicular cancer. Future studies need to improve exposure assessment and develop ways to adjust for possible prenatal factors.

  19. Sarcoidose testicular: um diagnóstico a ser considerado / Testicular sarcoidosis: a diagnosis to be considered

    Scientific Electronic Library Online (English)

    Vanderlei, Real; Guilherme Locks de, Loyola; Paulo Eduardo, Zanoni; Lara Flório, Real.

    2011-04-01

    Full Text Available [...] Abstract in english Sarcoidosis is a disease of unknown etiology, characterized by the presence of noncaseating granulomas in multiple organs. We present a case of testicular sarcoidosis in a white, 55-year-old man who has come to our department complaining of bilateral testicular discomfort and weight loss. [...

  20. Quiste de uraco infectado en edad infantil / Infected urachal cyst during childhood

    Scientific Electronic Library Online (English)

    V., Gimeno Argente; C., Domínguez Hinarejos; A., Serrano Durbá; F., Estornell Moragues; M., Martínez Verduch; F., García Ibarra.

    2006-12-01

    Full Text Available Los quistes de uraco son anomalías congénitas detectadas con mayor frecuencia en la infancia. Suelen manifestarse cuando se infectan, simulando diversas patologías agudas intraabdominales o pélvicas. Presentamos un caso en una niña de 7 años diagnosticada de quiste de uraco infectado. Analizamos el [...] origen embriológico de esta patología, sus formas de presentación clínica y sus aspectos diagnóstico-terapéuticos. Abstract in english Urachal cysts are congenital anomalies detected predominantly during the childhood. They are often diagnosed when an infection occur mimicking a variety of acute intra-abdominal or pelvic processes. We present a case in a 7-year-old female infant, diagnosed of infected urachal cyst. The embryologic [...] origin of this anomaly, clinical features, diagnosis and treatment are discussed.

  1. Quiste mesentérico en el recién nacido Mesenteric cyst present in newborn

    Directory of Open Access Journals (Sweden)

    Eduardo Morales Mesa

    2009-09-01

    Full Text Available El quiste mesentérico es una enfermedad rara en la etapa neonatal, y suele confundirse imagenológicamente con múltiples patologías de los órganos intraabdominales. Se presenta un caso clínico con diagnóstico prenatal por imagen anecoica del hemiabdomen superior. El paciente requirió múltiples intervenciones quirúrgicas por presentar un quiste mesentérico que coexistía con atresia intestinal ileal en forma de «cáscara de manzana», y el tratamiento clínico y nutricional fue difícil.Mesenteric cyst is a rare condition in neonatal stage and often is confounded with multiple pathologies of intra-abdominal organs. A clinical case diagnosed with prenatal diagnosis by anechoic image of superior hemi-abdomen. Patient required of many surgical interventions due to a mesenteric cyst coexisting with an "apple shell" ileal intestinal atresia. Clinical and nutritional treatment was difficult.

  2. Quiste mesentérico en el recién nacido / Mesenteric cyst present in newborn

    Scientific Electronic Library Online (English)

    Eduardo, Morales Mesa; Nilvia Esther, González García; Maria de los Ángeles, Cubero Rego; Lissette, Trelles Porro.

    2009-09-01

    Full Text Available El quiste mesentérico es una enfermedad rara en la etapa neonatal, y suele confundirse imagenológicamente con múltiples patologías de los órganos intraabdominales. Se presenta un caso clínico con diagnóstico prenatal por imagen anecoica del hemiabdomen superior. El paciente requirió múltiples interv [...] enciones quirúrgicas por presentar un quiste mesentérico que coexistía con atresia intestinal ileal en forma de «cáscara de manzana», y el tratamiento clínico y nutricional fue difícil. Abstract in english Mesenteric cyst is a rare condition in neonatal stage and often is confounded with multiple pathologies of intra-abdominal organs. A clinical case diagnosed with prenatal diagnosis by anechoic image of superior hemi-abdomen. Patient required of many surgical interventions due to a mesenteric cyst co [...] existing with an "apple shell" ileal intestinal atresia. Clinical and nutritional treatment was difficult.

  3. Quiste residual gigante: presentación de un caso / Residual cyst: a case presentation

    Scientific Electronic Library Online (English)

    Oscar, Rivero Pérez; Carlos, Albornoz López del Castillo; Isidro de Jesús, Nápoles González.

    2014-10-15

    Full Text Available Fundamento: un quiste es una estructura con tendencia a la forma redondeada, constituida por una pared externa de tejido conectivo fibroso, una pared interna formada por un tapiz epitelial. La cavidad quística contiene un material líquido o semilíquido de color cetrino que, cuando se infecta, se con [...] vierte en purulento y carmelitoso. El quiste residual puede haber sido anteriormente un quiste lateral o un quiste apical y al haberse extraído el diente, a partir de cuyo periodonto se forma el quiste, se queda en el tejido óseo sin haber sido extirpado. Objetivo: presentar un caso al cual se le diagnosticó y trató un quiste residual mandibular que abarcaba la hemiarcada izquierda, que permitió restablecer las funciones masticatorias y estética. Caso Clínico: paciente que fue atendido en la consulta de Cirugía Maxilofacial de la Facultad de Estomatología de Camagüey, con un aumento de volumen en la región lateral izquierda, con antecedentes de trauma anterior que le provocó fractura de mandíbula. Se describen las características clínicas de la enfermedad y el tratamiento quirúrgico realizado, se utilizó para el mismo los principios de la técnica de enucleación. Conclusiones: aunque se han reportados pocos casos en la literatura nacional y extranjera, estos han sido quistes de menor tamaño que incluyen uno o dos dientes, no existen reportes de quistes residuales que involucren toda la arcada o hemiarcada dentaria. Se obtuvieron resultados estéticos satisfactorios con la técnica quirúrgica empleada y no se presentaron complicaciones. Abstract in english Background: a cyst is a structure with a tendency to be rounded, made up of an external wall of fibrous connective tissue, an internal wall composed of epithelial tissue. The cystose cavity contains sallow liquid or semiliquid material that, when becomes infected, gets purulent and brown. A residual [...] cyst could have been previously a lateral cyst or an apical cyst and when the tooth is extracted from the periodontium, the cyst remains in the osseous tissue without being removed. Objective: to present a case diagnosed and treated for a mandibular residual cyst that extended over the left hemiarcade. It was possible to re-establish the masticatory and aesthetic functions. Clinical case: a patient who was treated in the Maxillofacial Surgery consultation of the Faculty of Stomatology of Camagüey. The patient presented a volume increase in the left lateral region and an antecedent of front trauma that caused fracture of the lower jaw. The clinical characteristics of the disease and the surgical treatment conducted are described. The principles of the enucleation technique were used for conducting the surgical treatment. Conclusions: in spite of the fact that few cases have been reported in the national and foreign literature, these have been smaller cysts that included one or two teeth. There are no reports of residual cysts that extend over all the dental arcade or hemiarcade. Satisfactory aesthetic results were obtained with the surgical technique applied and there were no complications.

  4. Quiste dermoide del suelo de la boca / Dermoid cyst in the mouth floor

    Scientific Electronic Library Online (English)

    Ayelén María, Portelles Massó; Ailín Tamara, Torres Íñiguez.

    2010-12-01

    Full Text Available El quiste dermoide representa menos del 0,01 % de todos los quistes de la cavidad bucal. Su ubicación más frecuente es en suelo de boca. Se presenta el caso de una paciente femenina de 19 años de edad que hacía aproximadamente 7 años había notado un aumento de volumen debajo de la lengua, el cual le [...] crecía paulatinamente y ya se apreciaba por fuera de la cara. Además, le ocasionaba molestias al hablar y al masticar. Se realizaron estudios complementarios y bajo anestesia general nasotraqueal. Se procedió a su exéresis quirúrgica mediante un abordaje intrabucal, donde se obtuvieron excelentes resultados estéticos y funcionales. El diagnóstico histopatológico se correspondió con un quiste dermoide de suelo de boca. La paciente no ha tenido recurrencia de la lesión transcurridos tres años de la operación. El quiste dermoide de suelo de boca se presenta como una tumoración benigna de la línea media. La exéresis intrabucal demuestra beneficios estéticos y funcionales. Abstract in english The Dermoid cyst account for the 0.01 % of all cysts of buccal cavity. Its more frequent location is in the mouth floor. This is the case of a female patient aged 19 who approximately 7 years noted an increase of volume under tongue growing gradually and noting outside face and the discomfort at to [...] speak and to chew. Complementary studies were conducted and under general anesthesia a surgical exeresis was carried out by intrabuccal approach achieving excellent esthetic and functional results. Histopathologic diagnosis matched with a dermoid cyst of mouth floor. Patient has not lesion recurrence after three years after operation. We conclude that the Dermoid cyst of mouth floor appear as benign tumor of middle line. The intrabuccal exeresis demonstrates esthetic and functional benefits.

  5. Public awareness of testicular cancer and testicular self-examination in academic environments: a lost opportunity

    Directory of Open Access Journals (Sweden)

    Henry A. A. Ugboma

    2011-01-01

    Full Text Available BACKGROUND: Although testicular cancer is the most common cancer among 18- to 50-year-old males, healthcare providers seldom teach testicular self-examination techniques to clients, thus potentially missing opportunities for early detection. This form of cancer is easily diagnosable by testicular self-examination and is 96% curable if detected early. Periodic self-examination must be performed for early detection. Knowledge deficits and sociocultural norms contribute to low levels of health-related knowledge in most patients, resulting in undue delays before seeking medical advice. OBJECTIVE: Our aim is to assess the level of awareness of testicular cancer and the prevalence of the practice of testicular self-examination in academic environments to enable appropriate interventions. METHOD: A cross-sectional survey was administered to 750 consecutive males aged 18-50 years in three tertiary institutions in Port Harcourt from October 2008 to April 2009. RESULT: Knowledge or awareness of testicular cancer was poor. Almost all of the respondents were unaware that testicular lumps may be signs of cancer. A lump was typically construed as a benign carbuncle or something that could resolve spontaneously. The main factor contributing to respondents' lack of knowledge of testicular cancer was that few reported that they were "ever taught about testicular self-examination." CONCLUSION: Young adult men are unaware of their risk for testicular cancer, which is the most common neoplasm in this age group. Healthcare providers are not informing them of this risk, nor are they teaching them the simple early detection technique of self-examination of the testes.

  6. Selective apoptotic effect of Zelkova serrata twig extract on mouth epidermoid carcinoma through p53 activation

    OpenAIRE

    Kang, Hoe-Jin; JANG, YOUNG-JOO

    2012-01-01

    Apoptosis or programmed cell death plays an essential role in chemotherapy-induced tumor cell killing, and inducers of apoptosis are commonly used in cancer therapy. Treatment with Zelkova serrata extracts was performed in human gingival fibroblast (HGF), mouth epidermoid carcinoma cell (KB), lower gingival squamous cancer cell (YD38) and tongue mucoepidermoid carcinoma cells (YD15). We observed that extract prepared from Zelkova serrata twig selectively inhibited proliferation of various ora...

  7. [Epidermoid cyst of the spleen in children. Apropos of 2 cases].

    Science.gov (United States)

    Bourdelat, D; Le Gall, E; Jouan, H; Duval, J M; Babut, J M

    1983-01-01

    Two cases of epidermoid cyst of the spleen are reported. A splenectomy was necessary because the topography of the lesions was not consistent with a conservative procedure for this children fourteen and ten years old. The histological criteria and pathogenic hypotheses of this infrequent lesion are analysed. Ultrasonography and eventually computerized tomography bring the best findings concerning the topography and are useful for the surgical treatment. When it is possible, the partial conservation of the spleen is to be wished. PMID:6627538

  8. Epidermoid carcinomas of the anal margin treated by curative goal irradiation

    International Nuclear Information System (INIS)

    Purpose: to evaluate the toxicity, the local control rate and the survival of patients suffering of an epidermoid carcinoma of the anal margin treated by curative and conservative irradiation. Conclusion: the excision should be reserved for small tumors away from the anal canal. The curative radiotherapy is recommended for the tumors with incomplete resection and for that ones of big volume or localised near the anal canal. (N.C.)

  9. The place of radiotherapy in muco-epidermoid carcinomas of salivary glands in child

    International Nuclear Information System (INIS)

    As muco-epidermoid carcinomas are the most frequent tumours of salivary glands for child, the authors report the study of the role of radiotherapy. This study is based on a survey performed in 34 paediatric departments. The authors analyse the age and gender, the use of irradiation, the tumour location, the tumour grade and size, the use of surgery and of radiotherapy, and survival. Radiotherapy is beneficial for high grade tumours, but cannot be recommended for low and intermediate grades. Short communication

  10. What Are the Risk Factors for Testicular Cancer?

    Science.gov (United States)

    ... Do we know what causes testicular cancer? What are the risk factors for testicular cancer? A risk ... of a certain race/ethnicity Body size These are discussed in more detail below. Undescended testicle One ...

  11. Splenic Epidermoid Cyst during Pregnancy; Case Report and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Majid Forouzesh

    2013-10-01

    Full Text Available Cystic disease of the spleen is not frequently encountered in surgical practice. It is broadly classified as parasitic and non-parasitic, the latter being a rare entity. In this case report, an epidermoid cyst of spleen led to acute abdomen in young age pregnant woman is presented.A 26-year-old woman with 15 weeks gestational age second pregnancy referred to emergency ward with left upper quadrant pain and tenderness that ultra sonography revealed large cyst (100?110mm with internal echo in spleen in favor of hydatic cyst or abscess. The patient was managed medically for one week but developed her abdominal pain, epigastric fullness, anorexia and fever. New sonography was done for her and large cyst was detected in spleen (120?110mm. She had severe pain accompanied with anorexia and vomiting. Fetus was normal in sonography. Exploratory laprotomy with splenectomy was performed. Splenomegaly (200?130?90mm with a cyst without any adhesion and inflammation was detected. Histopathology examination showed epidermoid cyst of spleen. (140?10?90mm. Though splenic epidermoid cyst is an uncommon entity, it should be considered in the differential diagnosis of an abdominal mass in a young individual. An attempt should be made to preserve the spleen provided there is adequate parenchyma otherwise splenectomy is the rule.

  12. Radiosurgery of epidermoid tumors with gamma knife. Possiblity of radiosurgical nerve decompression

    International Nuclear Information System (INIS)

    Long-term results of radiosurgery for epidermoid tumors are reported. There are 7 cases including 2 males and 5 females, ages ranging from 6 to 46 (mean: 33.3 years). At radiosurgery whole tumor was covered in 4 cases and partially covered in 3 cases in attempting to relieve cranial nerve signs like trigeminal neuralgia and facial spasm. The mean maximum and marginal doses were 25.6 Gy and 14.6 Gy respectively. In the mean follow-up of 52.7 months, all the tumors showed good tumor control without any progression and tumor shrinkage has been confirmed in 2 out of the 7 cases. Symptomatic trigeminal neuralgia improved or disappeared in all 4 cases and facial spasm disappeared in one. No neurological deterioration was found in any of the cases after the treatment. In conclusion, it is apparent that epidermoid tumors do respond well to radiosurgery and the accompanying hyperactive dysfunction of cranial nerves is significantly improved by gamma knife treatment with either entire or partial tumor coverage. Therefore the radiosurgical nerve decompression for epidermoid tumor seems to be achieved by gamma-radiosurgery. (author)

  13. Prognostic significance of s-phase fraction detected by antithymidine antibodies in epidermoid cervix carcinomas

    International Nuclear Information System (INIS)

    Purpose: To assess the predictive value of pretreatment proliferative activity of epidermoid cervix carcinoma cells with respect to short- and long-term results of radiotherapy. Methods and Materials: The proliferative activity of 25 epidermoid cervix carcinomas was evaluated as the immunofluorescent labelling index (LI) by rabbit antithymidine antibodies reacting specifically with single-stranded DNA of replication forks in S-phase cells. The short-term clinical outcome was estimated at 3-6 months after treatment by visual and palpatory examination. Three-year follow-up data were obtained through hospital charts and correspondence with referring physicians for only 19 patients. Results: There was no statistically significant association between LI and such conventional prognostic factors as clinical stage. The LI value of cervix carcinomas was significantly associated with complete regression at 3-6 months after radiotherapy and 3-year disease-free survival. Complete regression at 3-6 months was observed in 87.5% patients with fast proliferating tumors (LI > 7.0%), and only in 41.2% patients with slowly proliferating tumors (p = 0.03). Probability of 3-year disease-free survival was 85.7% in patients with fast proliferating tumors and 50.0% in those with slowly proliferating tumors (p = 0.05). Conclusions: The immunofluorescent LI of epidermoid cervix carcinoma is able to provide prognostic information on short-term tumor response to radiotherapy and disease-free survival

  14. Evaluation of radiotherapy and chemoradiotherapy for anal canal epidermoid cancer in our center

    International Nuclear Information System (INIS)

    The efficacy and safety of radiotherapy (RT) and chemoradiotherapy (CRT) for anal canal epidermoid cancer were evaluated. Twenty-four patients with anal canal epidermoid cancer were treated in our center between 1988 and 2006, consisting of 13 patients treated by RT and 11 by CRT. In these patients, the efficacy and safety of RT and CRT were evaluated in terms of adverse events, 5-year local control rates, 5-year disease-free survival rates, and 5-year survival rates. No grade 3 or higher adverse events were noted in patients receiving RT. In contrast, anorexia, diarrhea, neutropenia, and anemia were observed in 33.3%, 10%, 33.3%, and 10%, respectively, of the patients receiving CRT. The anal preserving rate, 5-year local control rate, 5-year disease-free survival rate, and 5-year survival rate were 66.7%, 73%, 77.5%, and 88.4%, respectively. RT and CRT for anal canal epidermoid cancer should be first-line treatments because of their safety and efficacy. (author)

  15. Isolated thoracic (D5) intramedullary epidermoid cyst without spinal dysraphism: A rare case report.

    Science.gov (United States)

    Mishra, Sudhansu Sekhar; Satapathy, Mani Charan; Deo, Rama Chandra; Tripathy, Soubhagya Ranjan; Senapati, Satya Bhusan

    2015-01-01

    Spinal epidermoid cyst, congenital or acquired, is mainly congenital associated with spinal dysraphism, rarely in isolation. Intramedullary epidermoid cysts (IECs) are rare with less than 60 cases reported so far; isolated variety (i.e., without spinal dysraphism) is still rarer. Complete microsurgical excision is the dictum of surgical treatment. A 14-year-old boy presented with 4-month history of upper backache accompanied with progressive descending paresthesia with paraparesis with early bladder and bowel involvement. His condition deteriorated rapidly making him bedridden. Neurological examination revealed upper thoracic myeloradiculopathy probably of neoplastic origin with sensory localization to D5 spinal level. Digital X-ray revealed no feature suggestive of spinal dysraphism. Contrast magnetic resonance imaging (MRI) characteristics clinched the presumptive diagnosis. Near-total microsurgical excision was done leaving behind a small part of the calcified capsule densely adhered to cord. Histopathological features were confirmative of an epidermoid cyst. Postoperatively, he improved significantly with a gain of motor power sufficient to walk without support within a span of 6 months. Spinal IECs, without any specific clinical presentation, are often diagnosed based upon intraoperative and histopathological findings, however early diagnosis is possible on complete MRI valuation. Complete microsurgical excision, resulting in cessation of clinical progression and remission of symptoms, has to be limited to sub-total or near-total excision if cyst is adherent to cord or its confines. PMID:26167216

  16. Aplicación de la técnica de Karapandzic en un carcinoma epidermoide del labio inferior / Application of Karapandzic Technique on Lower Lip Epidermoid Carcinoma

    Scientific Electronic Library Online (English)

    Maribel, Castillo Ramos; Ricardo, Aldana Mendoza; Victoria Cecilia, Orellana Pérez; Suleija, Estrada Domínguez; Aracelis, Viñals Legrá.

    2014-06-01

    Full Text Available En el Hospital Docente Dr. Guillermo Luís Fernández Hernández Baquero del municipio de Moa, fue atendida en enero de 2012 una paciente de 65 años de edad por presentar una lesión exofítica, infiltrante que ocupaba dos tercios del labio inferior que se extendía a piel. Se establece como impresión dia [...] gnóstica un carcinoma epidermoide y se decide el tratamiento quirúrgico. Atendiendo a las características individuales de la paciente se eligió la técnica descrita por Karapandzic, esta mantiene el pedículo vasculo-nervioso excelente, ofrece una alta frecuencia de curación y tiene resultados cosméticos-funcionales satisfactorios. Se retiró la sutura a los siete días, no se observaron complicaciones de los colgajos. Abstract in english A 65 -year- old woman showing an intense exophytic injury covering two third part of her lower lip and extended to the skin, was consulted at ?Guillermo Luis Fernández Hernández Baquero? Hospital, Moa locality, on January 31st , 2012. An epidermoid carcinoma was diagnosed and the surgical treatment [...] was determined to give. Karapandzic technique was selected according to the patient´s characteristics. This technique mainteain the vasculo-nerve pedicle in excellent conditions and provides high cure frequency and satisfactory cosmetics results. The suture was removed after seven days and no complications of the flaps were observed.

  17. Carcinoma epidermoide de canal anal estádio IV: complicações clínicas de doença avançada Epidermoid carcinoma of anal canal stage IV: clinical complications of advanced disease

    Directory of Open Access Journals (Sweden)

    Fernanda Bellotti Formiga

    2010-12-01

    Full Text Available O carcinoma anal é uma entidade rara que representa 4% dos tumores malignos da região anorretal, dentro os quais o carcinoma epidermoide constitui o tipo histológico mais comum. É relatado o caso de um paciente masculino, 54 anos, com carcinoma epidermoide de canal anal localmente avançado e com metástases ósseas no diagnóstico, feito após complicação infecciosa local com repercussão sistêmica. Descrevemos a evolução do paciente após o diagnóstico da neoplasia e as dificuldades de manejo clínico enconradas neste caso que são secundárias às complicações inerentes à doença de base.Anal carcinoma is a rare entity that represents 4% of anorectal malignant tumors, and the squamous cell carcinoma is the most common histological type. We report the case of 54-year-old male patient with locally advanced squamous cell carcinoma of the anal canal and metastatic bone disease at diagnosis, which was made after local infectious complications with systemic impact. We describe the evolution of the patient after the diagnosis and the difficulties of clinical management that are secondary to the complcations related to the underlying disease.

  18. Carcinoma epidermoide de canal anal estádio IV: complicações clínicas de doença avançada / Epidermoid carcinoma of anal canal stage IV: clinical complications of advanced disease

    Scientific Electronic Library Online (English)

    Fernanda Bellotti, Formiga; Alessandra Vicentini, Credidio; Daltro Lemos, Rosa; José César, Assef; Chia Bin, Fang; Peretz, Capelhuchnik; Wilmar Artur, Klug.

    2010-12-01

    Full Text Available O carcinoma anal é uma entidade rara que representa 4% dos tumores malignos da região anorretal, dentro os quais o carcinoma epidermoide constitui o tipo histológico mais comum. É relatado o caso de um paciente masculino, 54 anos, com carcinoma epidermoide de canal anal localmente avançado e com met [...] ástases ósseas no diagnóstico, feito após complicação infecciosa local com repercussão sistêmica. Descrevemos a evolução do paciente após o diagnóstico da neoplasia e as dificuldades de manejo clínico enconradas neste caso que são secundárias às complicações inerentes à doença de base. Abstract in english Anal carcinoma is a rare entity that represents 4% of anorectal malignant tumors, and the squamous cell carcinoma is the most common histological type. We report the case of 54-year-old male patient with locally advanced squamous cell carcinoma of the anal canal and metastatic bone disease at diagno [...] sis, which was made after local infectious complications with systemic impact. We describe the evolution of the patient after the diagnosis and the difficulties of clinical management that are secondary to the complcations related to the underlying disease.

  19. Dilema en el diagnóstico de quiste de colédoco: Reporte de un caso

    Scientific Electronic Library Online (English)

    A, Arrieta; A, Manzano; D, Navarro; R, Durango.

    2011-09-01

    Full Text Available El quiste de colédoco es una malformación congénita de las vías biliares poco común, que suele presentarse en la infancia. La triada clásica de ictericia, masa y dolor abdominal no siempre esta presente. Caso clínico: escolar femenina de 9 años, con Pancreatitis Aguda de evolución tórpida, ecosonogr [...] ama abdominal inicial sin alteraciones, y diagnóstico no concluyente de Colecistitis crónica o Colangitis alitiásica por tomografía abdominal y colangioresonancia, respectivamente. Referida para colangiopancreatografía retrograda endoscópica, estudio que fue omitido por ecosonograma abdominal control sugestivo de Quiste de colédoco. Se solicita nueva colangioresonancia, que no visualiza quiste y reporta dilatación de hepatocoledoco y colédoco terminal de aspecto afinado. Se mantiene conducta expectante. La paciente permanece asintomática, con reevaluación 3 meses después. El ecosonograma abdominal revelo: dilatación fusiforme del colédoco en toda su extensión, hallazgo compatible con quiste de colédoco tipo I. Se realiza resección del quiste, con buena evolución clínica. Se concluye que el uso de estudios por imágenes no invasivos son de utilidad en la evaluación hepatobiliar en niños, y el ultrasonido abdominal continua como método de elección para esta patología. Abstract in english Choledochal cyst is a congenital malformation of the bile ducts rare, usually seen in childhood. The classic triad of jaundice, abdominal mass and pain is not always present. Case report: A school girl of nine years, with Acute Pancreatitis torpid, unaltered initial abdominal ultrasound, and no conc [...] lusive diagnosis of chronic cholecystitis or acalculous cholangitis abdominal and from magnetic resonance tomography, respectively. Referred for endoscopic retrograde cholangiopancreatography, a study that was omitted from control abdominal ultrasound suggestive of choledochal cyst. New requested from magnetic resonance, which displayed no reports cyst and bile duct dilation and terminal hepatocoledoco related aspects. Expectant management is maintained. The patient remains asymptomatic, with reassessment 3 months later. The abdominal ultrasound revealed: fusiform dilatation of the bile duct in its entirety, a finding compatible with type I choledochal cyst Resection was performed, the cyst, cholecystectomy and reconstruction of the bile duct through a hepato-jejunostomy Roux en Y no complications. Liver biopsy reported normal tissue. We conclude that the use of noninvasive imaging tests such as ultrasound is the method of choice due to its sensitivity to determine the presence of cyst and to demonstrate the anatomy of the pancreatic’duct.

  20. MANEJO LAPAROSCÓPICO DE QUISTES OVÁRICOS COMPLICADOS O PERSISTENTES DURANTE EL EMBARAZO

    Scientific Electronic Library Online (English)

    José Luis, Troncoso J; Paolo, Ricci A; Jaime, Albornoz V; Antonio, Mackenna I.

    Full Text Available Antecedentes: El incremento en el hallazgo de quistes anexiales durante el embarazo sería el mayor uso de técnicas de reproducción asistida con hiperestimulación ovárica controlada. La complicación más frecuente sigue siendo la torsión anexial. Objetivo: Revisar el manejo de quistes anexiales compli [...] cados o persistentes, durante el embarazo, con resolución laparoscópica. Método: Revisión retrospectiva de 9 pacientes consecutivas, ingresadas al Departamento de Obstetricia y Ginecología Clínica Las Condes. Resultados: La edad gestacional de ingreso fue entre 5+5 y 27 semanas. Cinco casos fueron producto de fertilización asistida y cuatro espontáneos. Ocho (85,6%) embarazadas, ingresaron por dolor abdominal agudo. Otro caso ingresó a cirugía electiva por quiste ovárico persistente. Los quistes tenían entre 6 y 13 cm. En 5 se realizó sólo destorsión ovárica, en 1 ooforectomía y en 1 quistectomía. Se realizó punción, destorsión y fijación a ligamento útero ovárico, bilateral, en la otra paciente. Se registró un caso de fiebre en el postoperatorio. El alta hospitalaria fue a las 48 horas en 6 (67%), a las 72 en 2 y a las 96 en 1. El estudio biópsico diferido en 3 pacientes demostró: 1 quiste seroso paratubario, 1 quiste luteínico parcialmente hemorrágico y 1 infarto anexial. Todos los embarazos evolucionaron normalmente. Conclusión: Nuestra experiencia confirma que en el embarazo la laparoscopía es una buena opción al requerir una cirugía por quiste anexial complicado o persistente. Abstract in english Background: Recent reviews show an increase in the finding of adnexal cysts during pregnancy. One reason could be the use of assisted reproductive techniques with controlled ovarian hyperstimulation. Objective: To review the experience in managing via laparoscopy complicated or persistent adnexal cy [...] sts during pregnancy. Method: Retrospective review of 9 consecutive patients, admitted at the Department of Obstetrics and Gynecology, Clínica Las Condes. Results: The gestational age was between 5+5 and 27 weeks. Five were the product of assisted fertilization and four spontaneous. Eight (85.6%) pregnant women were admitted by emergency room because of acute abdominal pain and another one went through elective surgery for persistent ovarian cyst. Preoperative diagnosis of the 8 patients admitted by emergency: adnexal cyst complicated with torsion in 6 (1 adnexal infarction) and 2 cases of acute abdomen. The cysts were between 6 and 13 cm. Type of surgery: in 5, only detorsión; ovarian oophorectomy in 1 and cystectomy in one. Puncture, detorsión and bilateral fixation of uterine ovarian ligament, in another patient. One case required conversion to laparotomy with adnexectomy. Postoperative fever was observed in one patient. Discharge was at 48 hrs in 6 (67%) cases, at 72 hrs. in 2 and 96 hrs. in 1. Deferred biopsy performed in 3 patients showed: paratu-barian serous cyst, partially hemorrhagic luteal cyst, adnexal infarction. All pregnancies went on normally. Premature births are not reported. Conclusion: Our experience suggests that laparoscopic approach is a valid option for complicated or persistent adnexal cysts in pregnant women.

  1. MANEJO LAPAROSCÓPICO DE QUISTES OVÁRICOS COMPLICADOS O PERSISTENTES DURANTE EL EMBARAZO

    Directory of Open Access Journals (Sweden)

    José Luis Troncoso J

    2009-01-01

    Full Text Available Antecedentes: El incremento en el hallazgo de quistes anexiales durante el embarazo sería el mayor uso de técnicas de reproducción asistida con hiperestimulación ovárica controlada. La complicación más frecuente sigue siendo la torsión anexial. Objetivo: Revisar el manejo de quistes anexiales complicados o persistentes, durante el embarazo, con resolución laparoscópica. Método: Revisión retrospectiva de 9 pacientes consecutivas, ingresadas al Departamento de Obstetricia y Ginecología Clínica Las Condes. Resultados: La edad gestacional de ingreso fue entre 5+5 y 27 semanas. Cinco casos fueron producto de fertilización asistida y cuatro espontáneos. Ocho (85,6% embarazadas, ingresaron por dolor abdominal agudo. Otro caso ingresó a cirugía electiva por quiste ovárico persistente. Los quistes tenían entre 6 y 13 cm. En 5 se realizó sólo destorsión ovárica, en 1 ooforectomía y en 1 quistectomía. Se realizó punción, destorsión y fijación a ligamento útero ovárico, bilateral, en la otra paciente. Se registró un caso de fiebre en el postoperatorio. El alta hospitalaria fue a las 48 horas en 6 (67%, a las 72 en 2 y a las 96 en 1. El estudio biópsico diferido en 3 pacientes demostró: 1 quiste seroso paratubario, 1 quiste luteínico parcialmente hemorrágico y 1 infarto anexial. Todos los embarazos evolucionaron normalmente. Conclusión: Nuestra experiencia confirma que en el embarazo la laparoscopía es una buena opción al requerir una cirugía por quiste anexial complicado o persistente.Background: Recent reviews show an increase in the finding of adnexal cysts during pregnancy. One reason could be the use of assisted reproductive techniques with controlled ovarian hyperstimulation. Objective: To review the experience in managing via laparoscopy complicated or persistent adnexal cysts during pregnancy. Method: Retrospective review of 9 consecutive patients, admitted at the Department of Obstetrics and Gynecology, Clínica Las Condes. Results: The gestational age was between 5+5 and 27 weeks. Five were the product of assisted fertilization and four spontaneous. Eight (85.6% pregnant women were admitted by emergency room because of acute abdominal pain and another one went through elective surgery for persistent ovarian cyst. Preoperative diagnosis of the 8 patients admitted by emergency: adnexal cyst complicated with torsion in 6 (1 adnexal infarction and 2 cases of acute abdomen. The cysts were between 6 and 13 cm. Type of surgery: in 5, only detorsión; ovarian oophorectomy in 1 and cystectomy in one. Puncture, detorsión and bilateral fixation of uterine ovarian ligament, in another patient. One case required conversion to laparotomy with adnexectomy. Postoperative fever was observed in one patient. Discharge was at 48 hrs in 6 (67% cases, at 72 hrs. in 2 and 96 hrs. in 1. Deferred biopsy performed in 3 patients showed: paratu-barian serous cyst, partially hemorrhagic luteal cyst, adnexal infarction. All pregnancies went on normally. Premature births are not reported. Conclusion: Our experience suggests that laparoscopic approach is a valid option for complicated or persistent adnexal cysts in pregnant women.

  2. Quistes foliculares en vacas posparto y su evolución con tratamiento de GnRH Y PGF2

    Directory of Open Access Journals (Sweden)

    Leonardo Duque Muñoz

    2011-01-01

    Full Text Available Introduccion. Se analizaron retrospectivamente datos reproductivos en un lapso de tiempo cercano a 18 meses, en cinco hatos lecheros del municipio de San Pedro de los Milagros (Ant, con una poblacion de 950 vacas. Objetivo. Analizar la evolucion del tratamiento a vacas con quistes foliculares. Materiales y metodos. Las vacas fueron tratadas con GnRH a doble dosis y a los 14 dias PGF2¿¿. Si persistio el quiste se repitio dos veces mas el tratamiento. Analisis estadistico. Los datos fueron analizados utilizando el software SAS con un Anova, considerando como significativos todos los datos con un p<0,05. Resultados. Se encontro una frecuencia de presentacion de quistes en posparto tardio de 8,9 %; el porcentaje de vacas que resolvieron el problema al primer tratamiento fue de 74,1 %, con un promedio de 87,3 dias de diagnostico posparto, al segundo 10,5 % con 141,8 dias promedio y 3,5 % al tercero con 189,3 dias al diagnostico; el porcentaje de vacas descartadas fue de 11,8 %. Conclusiones. Este analisis retrospectivo de cinco hatos lecheros, demuestra que se presentan con relativa frecuencia quistes foliculares en el posparto tardio, pero se pueden solucionar efectivamente si se diagnostican en los primeros 90 dias, ademas el tratamiento realizado despues de detectado el quiste folicular entre 80-90 dias posparto, es efectivo para resolver el 74,12% de los casos, con una tasa de prenez del 70,5%.

  3. Segmental testicular infarction following cysto-prostatectomy

    Directory of Open Access Journals (Sweden)

    Alleemudder Adam

    2011-01-01

    Full Text Available Segmental (partial testicular infarction is a very rare condition of unknown cause in more than 70% of cases. Several predisposing conditions have been described, but to our knowledge, this is the first documented case and often overlooked complication occurring as a result of cysto-prostatectomy. It usually presents in an acute manner resembling testicular torsion or epididymo-orchitis and is confirmed using ultrasonography. In some cases, it may present insidiously with no pain and may be confused with a testicular tumor due to the hypo-echoic features on imaging. In unclear situations, Doppler sonography shows vascularity and a magnetic resonance scan can be useful to distinguish between the two conditions.

  4. Infarto segmentario de testículo / Segmentary testicular infarction

    Scientific Electronic Library Online (English)

    José María, Sánchez Merino; José Carlos, López Pacios; María del Carmen, Piñeiro Fernández; Sergio Carlos, Gómez Cisneros; Jesús, García Alonso.

    2009-04-01

    Full Text Available Objetivo: Se presenta un nuevo caso de infarto segmentario de testículo. Métodos: Paciente de 52 años que solicitó valoración por dolor en hemiescroto izquierdo de varios días de evolución. En la exploración física presentaba una induración palpable, dolorosa al tacto, en el polo superior del testíc [...] ulo izquierdo. Los marcadores tumorales (beta-hCG y alfa-fetoproteína) fueron normales. En el estudio ultrasonográfico se apreció una lesión nodular hipoecogénica intratesticular izquierda de 13 mm de diámetro, de bordes ligeramente irregulares, que no mostraba flujo en el análisis con Doppler color. Resultados: Con el diagnóstico de tumoración testicular izquierda se realizó orquiectomía por vía inguinal. Al corte dicha induración se correspondía con un nódulo bien delimitado. El estudio histopatológico mostró que la lesión correspondía a un infarto testicular segmentario, sin evidencia de malignidad ni signos de vasculitis. Conclusiones: La forma más habitual de diagnóstico del infarto segmentario de testículo se produce durante el estudio histopatológico de las piezas de orquiectomía radical realizadas por sospecha de tumor. La ultrasonografía con Doppler y la resonancia magnética nuclear tienen alta habilidad diagnóstica, si bien puede resultar difícil descartar categóricamente un tumor de testículo. En estos casos se puede recurrir a la exploración con biopsia que confirme la lesión isquémica no tumoral. Abstract in english Objective: A new case of segmental testicular infarction is reported. Methods: A 52-year-old man presented to the emergency department with severe pain in the left testicle over a few days period. Physical examination revealed a tender induration in the upper pole of the left testicle. [...] mbol>beta-human chorionic gonadotropin and alpha-fetoprotein were normal. Sonography demonstrated a poorly-defined, hypoechoic, 13 mm lesion. On power Doppler sonography, the hypoechoic area appeared completely avascular in contrast to the rest of the testicle. Results: Since testicular tumor was the initial diagnosis, the patient underwent a left radical orchiectomy. Pathological study revealed a focal testicular infarction, without signs of malignancy or vasculitis. Conclusions: Segmental testicular infarction is usually diagnosed after radical orchiectomy, performed when testicular tumor is suspected. On certain occasions Doppler ultrasound and magnetic resonance imaging findings suggested a segmental testicular infarction. However, if tumor cannot be entirely excluded, exploratory surgery is necessary.

  5. Grayscale and color Doppler features of testicular lymphoma.

    Science.gov (United States)

    Bertolotto, Michele; Derchi, Lorenzo E; Secil, Mustafa; Dogra, Vikram; Sidhu, Paul S; Clements, Richard; Freeman, Simon; Grenier, Nicolas; Mannelli, Lorenzo; Ramchandani, Parvati; Cicero, Calogero; Abete, Luca; Bussani, Rossana; Rocher, Laurence; Spencer, John; Tsili, Athina; Valentino, Massimo; Pavlica, Pietro

    2015-06-01

    Pooled data from 16 radiology centers were retrospectively analyzed to seek patients with pathologically proven testicular lymphoma and grayscale and color Doppler images available for review. Forty-three cases were found: 36 (84%) primary and 7 (16%) secondary testicular lymphoma. With unilateral primary lymphoma, involvement was unifocal (n = 10), multifocal (n = 11), or diffuse (n = 11). Synchronous bilateral involvement occurred in 6 patients. Color Doppler sonography showed normal testicular vessels within the tumor in 31 of 43 lymphomas (72%). Testicular lymphoma infiltrates through the tubules, preserving the normal vascular architecture of the testis. Depiction of normal testicular vessels crossing the lesion is a useful adjunctive diagnostic criterion. PMID:26014335

  6. Apéndices Testicular y Epididimario en Individuos Brasileños / Testicular and Epididymal Appendices in Brazilian Individuals

    Scientific Electronic Library Online (English)

    C. F, Sousa-Rodrigues; I. R. A, da Silva; M. V, Alves; F. T, Barbosa; M, del Sol; E, Olave; A. K. B, Ferreira-Rodrigues; E. A. N, Ribeiro.

    2014-09-01

    Full Text Available Los apéndices testiculares y epididimarios son remanescentes embriológicos del conducto paramesonéfrico y del conducto mesonéfrico, respectivamente. Estos apéndices pueden sufrir torsión causando un cuadro conocido como escroto agudo. El presente trabajo tuvo como objetivo determinar las variaciones [...] de los apéndices testicular y epididimario, registrando su forma y tamaño. Se utilizaron 30 cadáveres de indivíduos adultos, Brasileños, con edades comprendidas entre 18 y 70 años, fijados en formaldehído 40%, facilitados por el Laboratorio de Anatomía Descriptiva y Topográfica de la Universidad Federal de Alagoas (UFAL), Maceió, Brasil. A través de disección se identificó la presencia de los respectivos apéndices, los que fueron medidos con un caliper manual (MetricaR), registrando su longitud y anchura. Los apéndices testiculares fueron observados en 41 testículos (68,3%) y los apéndices epididimarios en 15 casos (25%). El promedio de la longitud fue de 4,9 mm (DE=1,7) para el apéndice testicular y de 5,2 mm (DE=2,4) para el epididimario. Con respecto a la anchura de los apéndices, el promedio registrado fue de 3,2 mm (DE=1,7) para el testicular y de 2,6 mm (DE=0,9) para el epididimario. Los datos obtenidos puede ser utlizados como soporte morfológico a la clínica urológica y cirugía testicular. Abstract in english Testicular and epididymal appendages are embryologic remnants of the mesonephric duct and paramesonephric, respectively. These appendices are subject to a torsion causing condition known as acute scrotal syndrome. This study aimed to determine the variations of testicular and epididymal appendices, [...] registering its presence and size. We studied 30 cadavers of adult individuals, Brazilians, aged 18 and 70, fixed in formaldehyde 40%, provided by the Laboratory of Descriptive and Topographic Anatomy of the Federal University of Alagoas (UFAL), Maceió, Brazil. By dissecting these, the presence of the respective appendixes were identified, which were measured with a manual caliper (Metrica), recording its length and width. The testicular appendices were observed in 41 testes (68.3%) and epididymal appendices in 15 cases (25%). The average length was 4.9 mm (SD=1.7) for the appendix testis and epididymis to 5.2 mm (SD=2.4). With respect to the width of the appendices, the average recorded were 3.2 mm (SD=1.7) and 2.6 mm (SD=0.9) for testicular and epididymal, respectively. The data obtained can be used as morphological support in urological clinical and testicular surgery.

  7. Long-term effects of prepubertal testicular vessel ligation on testicular function in the rat.

    Science.gov (United States)

    Pascual, J A; Villanueva-Meyer, J; Rutgers, J L; Lemmi, C A; Sikka, S C; Ehrlich, R M; Mena, I; Rajfer, J

    1990-08-01

    To determine the effects of unilateral testicular vein and artery ligation in the immature rat on the function and final location of the testis at adulthood, 10-day-old male rats underwent either a sham operation or unilateral ligation of these vessels of the still undescended testis. Testicular location, blood flow, size and histology as well as ventral prostate weights were measured 50 days later at adulthood. At age 60 days, it was determined that all testes were descended into the scrotum, and there were no differences in testis and ventral prostate weights, intratesticular sperm counts and mean seminiferous tubular area between the control and sham operated animals. However, there was an 18% reduction in testicular blood flow (ml. per 100 gm. per minute +/- standard error of mean) in the operated animals when compared to the sham (20.43 +/- 1.10 versus 16.69 +/- 0.74, p less than 0.02). These data indicate that although there is a slight but significant reduction in testicular blood flow at adulthood when the testicular artery and vein are ligated early in life, this diminution is not sufficient to alter the ultimate location, testicular weight and spermatogenic function of the testis. This would suggest that after ligation of the main testicular vessels to the immature testis, the collateral blood supply is able to compensate with time to allow normal growth and development of the testis. These experimental observations provide additional support for the 2-staged approach to the high undescended testis whereby the testicular vessels are initially ligated and a subsequent procedure is performed to place the undescended testis into the scrotum. PMID:2374222

  8. Quiste renal gigante. Presentación de un caso / Giant renal cyst. Presentation of a case

    Scientific Electronic Library Online (English)

    Teresa, Suárez Díaz; Yuniel, Arocha Molina; Ariel, Jordán Alonso; Roberto, Ruiz Reyes; Adianez, Jiménez Álvarez.

    2013-08-01

    Full Text Available En el riñón frecuentemente se desarrollan quistes. Dentro de la diversidad de quistes renales, el simple puede presentarse dentro del riñón o en la superficie de este pudiendo, ser único o múltiple, unilateral o bilateral y más frecuente en el izquierdo. Generalmente se manifiestan asintomático y pu [...] eden alcanzar gran tamaño, denominándose quistes gigantes. Se presenta un paciente de 66 años que ingresa por dolor lumbar hace un año, que empeora a pesar del tratamiento médico para una presunta sacrolumbalgia. En el abdomen se aprecia marcado aumento de volumen, sobre todo hacia el hemiabdomen superior y se palpa gran masa tumoral que ocupa la totalidad del hemiabdomen superior, renitente y no dolorosa. Se realizó tomografía axial computarizada de abdomen, apreciándose imagen hipodensa multitabicada que ocupa todo el hemiabdomen izquierdo con desplazamiento de asas, riñón izquierdo y músculo psoas. Se concluye como quiste gigante multitabicado de riñón izquierdo. Se realizó laparotomía paramediana izquierda supra e infraumbilical y se detecta gran quiste renal del polo superior del riñón izquierdo que sobrepasa la línea media desplazando la arteria aorta a la derecha de la columna vertebral. Se realizó nefrectomía izquierda. Es raro, que un quiste renal simple gigante, sobrepase la línea media y tenga compresión de tantos órganos intraabdominales; este es un hecho poco descrito en la literatura médica. El examen físico superficial y limitado al órgano que produce los síntomas que motivan la consulta, limita el diagnóstico precoz de muchas enfermedades como se demuestra en este paciente. Este es uno de los errores más frecuentes que se aprecian al aplicar el método clínico. Abstract in english Frequently, cysts develop in the kidney. Among the diversity of renal cysts, the simple one could be located inside the kidney or in its surface and may be single or multiple, unilateral or bilateral, and more frequent in the left kidney. Generally they are asymptomatic and can reach a great size, c [...] alled giant cysts. We present a patient aged 66 years, entering the hospital with lumbar pain of one year that gets worse despite the medical treatment for a presumed sacrolumbal pain. It was found a remarked increase of the abdomen volume, mainly in the direction of the upper hemiabdomen and it feels a big tumoral mass filling the totality of the upper abdomen, renitent and no painful. An abdominal computer tomography was carried out, finding a multi partitioned hypodense image filling all the left hemiabdomen with displacement of loops, left kidney and psoas muscle. We arrived to the conclusion that it was a giant multi partitioned cyst of the left kidney. A left paramedian supra and infra umbilical laparotomy was carried out finding a renal cyst of the upper pole of the left kidney surpassing media line and displacing aortal artery to the right of the spinal column. A left nephrectomy was carried out. It is rare a simple renal giant cyst surpassing the media line and compressing so many intra abdominal organs; this is a fact scarcely described in the medical literature. The surface physical examination restricted to the organ producing the symptoms that motivate the consultation, interferes the precocious diagnosis of many diseases as it is shown in this patient. This is one of the most frequent mistakes committed when applying the clinical method.

  9. Testicular function in boys after chemotherapy and/or testicular irradiation for acute leukemia and malignant lymphoma

    Energy Technology Data Exchange (ETDEWEB)

    Fujinami, Akira; Nakanishi, Yasushi; Nakagawa, Kimiko; Takubo, Yoshiyuki; Sako, Masahiro; Konishi, Shouzaburo (Osaka City General Hospital (Japan))

    1994-04-01

    Testicular function was investigated by testicular biopsy, testicular volume, testosterone and LH-RH test in 16 prepubertal boys with 15 cases of acute leukemia and one case of malignant lymphoma after chemotherapy and/or testicular irradiation. One of 2 cases who had infiltrated in testes received irradiation at onset. With another 2 cases, testis was resected at testicular relapse and irradiated on opposite side. All continued complete remission for 1-9 years after cessation of chemotherapy. Basal levels of serum testosterone, FSH and LH were normal in 13 cases of unirradiated group recently but spermatogonia in testicular biopsy specimen decreased on cessation of chemotherapy in 8 cases. Primary gonadal dysfunction was detected in 3 cases of irradiated group. And so testicular irradiation induced damage of tubular system and Leydig cell function. It is necessary to follow up about sexual maturation. (author).

  10. Retención aguda de orina, "RAO", como presentación de quiste de uraco / Urachal cyst presentated as acute urinary retention

    Scientific Electronic Library Online (English)

    C., Quicios Dorado; E., Fernández Fernández; I., Gómez García; D., García Flórez; C. de, Castro Guerin; A., Escudero Barrilero.

    2005-10-01

    Full Text Available El quiste de uraco esta presente aproximadamente en el 2% de los adultos, siendo su diagnostico difícil y secundario a las manifestaciones de su complicaciones. Presentamos un caso inusual de retención aguda de orina en un quiste de uraco, que debutó como dolor hipogástrico y anuria. [...] Abstract in english 2% of adults have an urachal cyst. The diagnosis is usually made due to its clinical complications. We report an inusual case of acute urinary retention due to an urachal cyst, with hipogastric pain and anuria as initial syntoms. [...

  11. Tratamiento del quiste óseo solitario con energía piramidal / Treatment of the solitary bone cyst with pyramidal energy

    Scientific Electronic Library Online (English)

    Reinaldo, Viera García; Martín, Rodríguez Barrios; Francisco, Carcasés Osorio; Eduardo, Borges Romero; Percyvals, Cabrera Feurtado.

    2009-12-01

    Full Text Available Se describe el caso clínico de una niña con fractura patológica recurrente a causa de un quiste óseo solitario en el tercio superior del húmero izquierdo. La aplicación de la energía piramidal constituyó una técnica terapéutica eficaz para eliminar el mencionado quiste. [...] Abstract in english The clinical case of a girl with recurrent pathological fracture due to a solitary bone cyst in the upper third of the left humerus is described. Application of pyramidal energy was an effective therapeutic technique to remove this cyst. [...

  12. Amputación interescapulotorácica por cromomicosis y carcinoma epidermoide / Amputation interscapulothracique pourchr4omomycose et6 carcinome épidermoide / Interscapulothoracic amputation by chromomycosis and epidermoid carcinoma

    Scientific Electronic Library Online (English)

    Hiralio, Collazo Álvarez; Eridán, González Velázquez; Andrés G, Pardillo Morales; Stephen Yecc, Collazo Marín.

    2001-12-01

    Full Text Available Paciente del sexo masculino y blanco de 74 años de edad, con lesión dermatológica hiperpigmentada y verrucosa de más de 25 años de evolución en codo y antebrazo izquierdo; asimismo posee otra de piel en forma de coliflor y cuya evolución es reciente. Ambas presentaron diagnóstico histopatológico de [...] cromomicosis. El tratamiento inicial fue la exéresis con margen oncológico de la lesión en forma de coliflor y la electrofulguración, curetaje del resto de la lesión y tratamiento antimicótico. En un período de 5 meses el enfermo presenta evolución tórpida con toma del estado general y elefantiasis del miembro superior izquierdo hasta región supraclavicular que obliga a realizarle amputación interescapulotorácica por la técnica de Berger para mejorar la calidad de vida. El diagnóstico histopatológico de los paquetes ganglionares resecados mostró metástasis de un carcinoma epidermoide. Abstract in english The case of a 74-year-old white male patient with a hyperpigmented and verrucose dermatological injury of more than 25 years of evolution in his left elbow and forearm is reported. He also has another cauliflower-like skin injury of recent evolution. Both presented histopathological diagnosis of chr [...] omomycosis. The initial treatment was exeresis with oncological margin of the cauliflower-like injury and electrofulguration, curettage of the rest of the injury and antimycotic treatment. In 5 months, the patient had a torpid evolution with taking of the general state and elephantiasis of the upper left extremity to the supraclavicular region that led to the interscapulothoracic amputation by Berger’s technique to improve his quality of life. The histopathological diagnosis of the resected ganglionar packages showed metastasis of an epidermoid carcinoma.

  13. Late onset Proteus Mirabilis Meningitis and Subdural Abscess in a Boy With Lumbosacral Epidermoid Tumor: Case Report

    Directory of Open Access Journals (Sweden)

    Ayfer GÖZÜ P?R?NÇÇ?O?LU

    2012-03-01

    Full Text Available Dermal sinus tracts have been reported all along the midline neuroaxis, with the majority being located in lumbar and sacral areas. They are usually associated with split cord malformations, tethered cord and inclusion tumors (dermoid, epidermoid, teratoma. Dermal sinus tracts with concomitant dermoid or epidermoid tumors are frequently associated with recurrent meningitis, but spinal subdural abscess is rare. The authors report a 2 years old boy with lumbar epidermoid tumor, late onset Proteus mirabilis meningitis and spinal intradural abscess, who had a history of a dermal sinus tract removal one year before his admission. The importance of early diagnosis, proper surgical and medical treatment and close follow up in such patients is stressed.

  14. Quiste de inclusión conjuntival gigante. Presentación de un caso / Cyst of inclusion conjunctival giant. Case presentation

    Scientific Electronic Library Online (English)

    Isabel, Medina Rodríguez; Beatriz, Zozaya Aldana; Henry, Pérez González; Yanet, García Concha; René Faustino, Espinosa Álvarez.

    2012-03-01

    Full Text Available Introducción: El Quiste de inclusión conjuntival gigante, forma parte de los quistes de inclusión epitelial, y en la literatura revisada solo se reportan esporádicos casos, asociados en la mayoría de ellos a cirugías previas, donde las células epiteliales son capturadas por la sutura e implantados e [...] n otros sitios Presentación del caso: Se describe el caso en paciente de 19 años, piel negra, oriunda de Malí, África, portadora de una lesión tumoral conjuntival, la cual recibió tratamiento médico sintomático durante 18 meses, sin resolución. Luego de evaluar el caso, se decide exéresis de la lesión con su posterior estudio anatomopatológico. Conclusiones: Se recibe el resultado con el diagnóstico confirmativo: quiste de inclusión conjuntival gigante. Se logró la recuperación total de la paciente. Se finaliza con un breve comentario de esta entidad a través de la literatura consultada. Abstract in english Introduction: The Cyst of conjunctival giant inclusion, form departs from the cysts of epithelial inclusion, and occasional cases, associates report themselves in literature checked only in the their majority to previous surgeries, where epithelial cells are captured by the suture and established at [...] another places. Case presentation: Describes him the case in patient of 19 years, black, native skin of Mali, Africa, beneficiary of a lesion conjunctival tumoral, which he received symptomatic medical treatment during 18 months, without resolution. Right after evaluating the case, makes a decision exéresis of the lesion with his posterior study anatomopatológico. Conclusions: The result with the confirmative diagnosis is received: Cyst of conjunctival giant inclusion. He got for himself the patient's total recuperation. It comes to an end with a brief comment of this entity through looked up literature.

  15. Quiste renal complejo: caso difícil de diagnosticar / Complex renal cyst: a difficult case to diagnose

    Scientific Electronic Library Online (English)

    Odalys, Sandoval Jiménez; Lourdes, Santana Sarrhy.

    2009-12-01

    Full Text Available Se presenta un nuevo caso de un quiste renal complejo que acude a nuestro centro. La paciente tiene 59 años y hace poco tiempo presenta un dolor lumbar izquierdo mantenido, sordo y gravativo; al examen físico se palpa una tumoración en el hipocondrio y flanco izquierdo. Esta entidad no es rara, pero [...] es difícil de diagnosticar pues en múltiples estudios las imágenes complejas indican una posible afectación tumoral maligna y sólo la exploración quirúrgica define el diagnóstico real. Se describen las características de los quistes renales simples y complejos detallando cómo se realiza el diagnóstico imagenológico de estos casos y la conducta que se sigue en dependencia del grado de complejidad del quiste. Se compara la información encontrada en la literatura médica y la experiencia con esta paciente. Se revisa la literatura encontrada sobre el tema y se comenta la problemática en torno al diagnóstico y a las posibilidades terapéuticas. Abstract in english This is the case of a female patient coming to our center presenting with a complex renal cyst. The patient is aged 59 and a short history of a sustained, dull and severe left lumbar pain; at physical examination a hypochondrium tumor in left flank is palpated. This entity is frequent, but is diffic [...] ult to diagnose since in multiple studies complex images show possible malign tumor affection, and only the surgical exploration defines the true diagnosis. Features of the simple and complex renal cysts with details on performing of imaging diagnosis of these cases and the behavior followed according the complexity degree of cyst. Information present in medical literature is compared with experience of this patient. Literature on this matter is reviewed and problems around the diagnosis and the therapeutical possibilities are discussed.

  16. Quiste dermoide verdadero en piso de boca / True dermoid cyst in the floor of the mouth

    Scientific Electronic Library Online (English)

    Daniel, Antunes Freitas; Jessica, Lozano Perez; Luis, Fang Mercado; Antonio, Díaz Caballero.

    2013-09-01

    Full Text Available Los quistes dermoides son lesiones benignas de origen embrionario, con una incidencia del 0,01 % de todos los quistes de la cavidad bucal. No presenta predicción por sexo y alrededor del 60 % de los casos se desarrollan entre los 15 y 35 años de edad. El conocimiento de los hallazgos clínicos de est [...] e tipo lesiones es vital para un diagnóstico definitivo, sin embargo, este siempre debe ser corroborado mediante exámenes histopatológicos, especialmente, al realizar un diagnóstico diferencial entre los diferentes tipos de quiste dermoides u otras alteraciones a nivel oral con manifestaciones clínicas similares. El propósito de esta presentación reportar un caso clínico para ampliar conocimientos sobre el diagnóstico y tratamiento de este tipo de lesión debido a su infrecuencia en cavidad oral. La ubicación inusual de estos quistes en cavidad oral hace que, aún con una buena valoración clínica e imaginológica, el diagnóstico prequirúrgico preciso sea difícil. Es por esto que el tratamiento quirúrgico no sólo evita el riesgo de una complicación infecciosa y eventual malignización sino que permite obtener un diagnóstico definitivo mediante estudios histopatológicos. Abstract in english Dermoid cysts are benign lesions of embryonic origin, with an incidence of 0.01 % of all cysts in the oral cavity. There is no prediction by sex and about 60 % of cases develop at the age of 15 to 35 years old. Knowledge of the clinical findings of such injuries is vital for a definitive diagnosis; [...] however, this should always be confirmed by histopathological examination, especially when making a differential diagnosis between different types of dermoid cyst or other pathologies with similar clinical manifestations. The purpose of this article is to expand knowledge about the diagnosis and treatment of this type of injury because of it is not frequent in the oral cavity. The unusual location of these cysts in the oral cavity makes hard the precise preoperative diagnosis, even with good clinical and radio-graphical assessment. The surgical treatment not only prevents the risk of infectious complications and possible malignancy but also, allows obtaining a definitive diagnosis by a histopathological study.

  17. Splenic Epidermoid Cyst during Pregnancy; Case Report and Review of the Literature

    OpenAIRE

    Majid Forouzesh; Laleh Ghanbarzadegan; Masoomeh Rahimi; Leila Ghahramani

    2013-01-01

    Cystic disease of the spleen is not frequently encountered in surgical practice. It is broadly classified as parasitic and non-parasitic, the latter being a rare entity. In this case report, an epidermoid cyst of spleen led to acute abdomen in young age pregnant woman is presented.A 26-year-old woman with 15 weeks gestational age second pregnancy referred to emergency ward with left upper quadrant pain and tenderness that ultra sonography revealed large cyst (100?110mm) with internal echo in ...

  18. Tumor testicular bilateral "quemado" ("burn out") / Burn out bilateral testicular tumor

    Scientific Electronic Library Online (English)

    M.J., Mola Arizo; V., Gonzalvo Pérez; M.D., Torregrosa Maicas; J.A., Navarro Antón; A., Gómez-Ferrer Lozano; A., Estany Pérez; A.C., Polo Peris.

    2005-03-01

    Full Text Available Es difícil diferenciar entre tumor de células germinales retroperitoneal primario y enfermedad metastásica de un tumor gonadal indetectado o que ha regresado espontáneamente. Presentamos un caso clínico de "burn out" o tumor quemado, es decir un tumor retroperitoneal seminomatoso, metastásico con im [...] portantes alteraciones testiculares bilaterales tanto ecográficas como anatomopatológicas, pero sin evidenciar tumor. Pese a las controversias que detallamos, nuestra opción terapéutica fue la extirpación de la masa residual tras la quimioterapia asociada a orquiectomía bilateral en el mismo acto. Concluimos que ante un tumor retroperitoneal, la existencia de alteraciones ecográficas en los testículos, pese a una palpación normal, debe hacer pensar en un "Síndrome de burn out", siendo obligatoria la biopsia testicular bilateral. La exploración quirúrgica de los mismos e incluso la orquiectomía son opciones a valorar en función de cada paciente. Abstract in english Differentiating a primary retroperitoneal seminoma from a metastatic testicular tumor with an occult testicular primary or a burned out testicular cancer remains difficult. We present a case of a burned out tumor. The patient had a retroperitoneal seminoma with ultrasonically and pathologically demo [...] nstrated abnormalities in both testes, but without evidence of tumor. The patient received chemotherapy and underwent surgery of the residual retroperitoneal mass and bilateral orchiectomy. All surgical specimens were negative for testis cancer. Conclusion: Primary extragonadal germ cell tumors in the retroperitoneum are a rare entity. The presence of a retroperitoneal tumor with ultrasonographical abnormalities in testicular evaluation should be considered as a metastases of a burned out testicular cancer, and biopsy is mandatory. Surgical evaluation and orchiectomy should be evaluated in a individual setting.

  19. Fibroma ameloblástico versus quiste folicular hiperplásico / Ameloblastic fibroma versus hyperplastic follicular cyst

    Scientific Electronic Library Online (English)

    J., Azúa-Romeo; E., Saura Fillat; T., Usón Bouthelier; M., Tovar Lázaro; J., Azúa Blanco.

    2004-06-01

    Full Text Available Resumen: El fibroma ameloblástico (FA) es un tumor odontogénico mixto, compuesto por tejido mesenquimal y epitelio odontogénico, representando el 2% de los tumores odontogénicos, mientras que el quiste dentígero o folicular (QF), el segundo quiste odontogénico en frecuencia, está compuesto exclusiva [...] mente por tejido conjuntivo laxo (mesénquima), si bien, el saco fibroso puede contener restos de epitelio odontogénico incluidos, dando lugar a una imagen histológica muy similar. La importancia de esta diferenciación radica en el tratamiento, que es ligeramente más agresivo en el FA y en el comportamiento biológico, ya que el FA puede derivar en un sarcoma ameloblástico, y el QF puede evolucionar hacia ameloblastoma y más raramente carcinoma mucoepidermoide. Abstract in english Abstract: Ameloblastic fibroma (AF) is a mixed odontogenic tumor composed of mesenchymal tissue and odontogenic epithelium, accounting for 2% of all odontogenic tumors, while dentigerous or follicular cyst (FQ), second odontogenic cyst in frequency, is formed exclusivelly by soft conective tissue (m [...] esenchyme). Nevertheless, hiperplastic fibrous sac may contain rests of odontogenic epithelium, showing a similar histologic pattern. The importance of an adequate differentiation lies in the treatment, which is slightly aggresive for AF, and regarding the biological behaviour of both lesions, since AF might become in an ameloblastic sarcoma, while over an FQ could develope an ameloblastoma or even a mucoepidermoid carcinoma.

  20. Fibroma ameloblástico versus quiste folicular hiperplásico Ameloblastic fibroma versus hyperplastic follicular cyst

    Directory of Open Access Journals (Sweden)

    J. Azúa-Romeo

    2004-06-01

    Full Text Available Resumen: El fibroma ameloblástico (FA es un tumor odontogénico mixto, compuesto por tejido mesenquimal y epitelio odontogénico, representando el 2% de los tumores odontogénicos, mientras que el quiste dentígero o folicular (QF, el segundo quiste odontogénico en frecuencia, está compuesto exclusivamente por tejido conjuntivo laxo (mesénquima, si bien, el saco fibroso puede contener restos de epitelio odontogénico incluidos, dando lugar a una imagen histológica muy similar. La importancia de esta diferenciación radica en el tratamiento, que es ligeramente más agresivo en el FA y en el comportamiento biológico, ya que el FA puede derivar en un sarcoma ameloblástico, y el QF puede evolucionar hacia ameloblastoma y más raramente carcinoma mucoepidermoide.Abstract: Ameloblastic fibroma (AF is a mixed odontogenic tumor composed of mesenchymal tissue and odontogenic epithelium, accounting for 2% of all odontogenic tumors, while dentigerous or follicular cyst (FQ, second odontogenic cyst in frequency, is formed exclusivelly by soft conective tissue (mesenchyme. Nevertheless, hiperplastic fibrous sac may contain rests of odontogenic epithelium, showing a similar histologic pattern. The importance of an adequate differentiation lies in the treatment, which is slightly aggresive for AF, and regarding the biological behaviour of both lesions, since AF might become in an ameloblastic sarcoma, while over an FQ could develope an ameloblastoma or even a mucoepidermoid carcinoma.

  1. Giant Ovarian Cyst. A Case Report Quiste de ovario gigante. Presentación de un caso

    Directory of Open Access Journals (Sweden)

    Yarisdey Corrales Hernández

    2012-09-01

    Full Text Available Ovarian cysts are common tumors among gynecological conditions. The case of a 46 years old woman who arrived at the Dr. Gustavo Aldereguía Lima General University Hospital in Cienfuegos, because of pain and swelling of the abdomen of a year of evolution is presented. The physical examination and ultrasound were performed and the patient was diagnosed with an ovarian dependant cystic mass. Laparotomy was performed and the left ovarian cyst was resected. In pathological and anatomical studies the diagnosis of an ovarian serous cystadenoma was confirmed.Los quistes de ovario son tumoraciones frecuentes en las afecciones ginecológicas. Se presenta el   caso de una paciente de 46 años de edad, que acudió al Hospital General Universitario Dr. Gustavo Aldereguía Lima, de Cienfuegos, refiriendo dolor y aumento de volumen del abdomen de un año de evolución. Se realizaron examenes físico y ultrasonográfico, mediante los que se le diagnosticó una masa quística dependiente de ovario. Se practicó laparotomía y se resecó un quiste de ovario izquierdo. En su estudio anatomopatológico se comprobó el diagnóstico de cistoadenoma seroso del ovario.

  2. Quiste dermoide en la cola de la ceja / Dermoid cyst in the eyebrow tail

    Scientific Electronic Library Online (English)

    Lázara Kenia, Ramírez García; Datia Liset, Ortiz Ramos; Clara Gisela, Gómez Cabrera; Lázaro, Vigoa Aranguren; Irene, Rojas Rondón; Franklyn Alain, Abreu Perdomo.

    2014-03-01

    Full Text Available El quiste dermoide es un tipo de coristoma que corresponde a una anomalía congénita del desarrollo. Se presenta una transicional de dos años. Desde su nacimiento, la mamá notó un aumento de volumen a nivel de la cola de la ceja del ojo derecho, de bordes delimitados, blanda, movible, reborde orbitar [...] io libre, sin cambios de coloración, con un crecimiento acelerado clínico y ultrasonográfico en meses. Se decidió exéresis y biopsia para estudio anatomopatológico. Los resultados finales mostraron confirmación del diagnóstico de quiste dermoide en la cola de la ceja. La evolución posoperatoria fue satisfactoria sin recidiva de la lesión. Abstract in english The dermoid cyst is a type of choristoma resulting from congenital development anomaly. A 2-year transitional dermoid cyst from birth was discovered by the mother when she noticed increased volume at the tail of the right eyebrow, defined edges, soft, movable, free orbital rim, no color changes with [...] rapid clinical and ultrasonographic growth in months. It was decided to perform excision and biopsy for the pathological study. The final results showed confirmation of the diagnosis of dermoid cyst in tail of the eyebrow. The postoperative course was satisfactory without recurrent injure.

  3. Quiste de Tarlov bilateral, presentación de un caso / Tarlov cyst bilateral , case report

    Scientific Electronic Library Online (English)

    Octavio, Chávez Herbas; Luis Daniel, Parada Heredia; Tonchy, Marinkovic Álvarez.

    2014-12-01

    Full Text Available Los quistes de Tarlov, son crecimientos quísticos benignos sub diagnosticados y no reportándose ningún caso en Bolivia. Son clasificados como quistes meníngeos tipo II, infrecuentes (incidencia estimada de 4,6% - 9%), de características benignas, en su mayoría localizados en región sacra. Asintomáti [...] cos, en su gran mayoría diagnosticados de manera incidental. Se presenta el caso de una paciente con dolor crónico de tipo radicular en fosa iliaca izquierda sin mejoría ni explicación del mismo. Se le realizó tomografía computarizada y resonancia magnética por las cuales se llegó al diagnóstico. Posteriormente se da tratamiento conservador sintomatológico con mejoría evidente de las misma. No requiriendo tratamiento quirúrgico. Abstract in english Tarlov cyst is a benign cystic growth usually underdiagnosed. No case has been reported so far in Bolivia. Classified as a Type II meningeal cysts, rare (estimated incidence of 4,6% - 9%), of benign characteristics, most commonly located in the sacral region. Asymptomatic and diagnosed incidentally [...] most of the times. The patient comes with a chief complaint of chronic radicular back pain in the left iliac fossa with no improvement or explanation thereof. The patient underwent CT and MRI leading us to the diagnosis. The patient is managed with conservative treatment targeting the symptoms, with notorious improvement not requiring surgical treatment.

  4. Cáncer papilar primario en quiste del conducto tirogloso: A propósito de un caso

    Scientific Electronic Library Online (English)

    Ysmael, Vegas; José E, Goubaira; Wilfredo, Perfetti; Juan, Scarton López; José G, López; Verónica, Mora.

    2006-03-01

    Full Text Available El conducto tirogloso es una anomalía congénita resultado de la retención del tracto epitelial entre la tiroides, el foramen cecum y el piso de la faringe. La aparición de un carcinoma en el quiste del conducto tirogloso es rara. Hasta donde sabemos se han publicado 150 casos en la literatura intern [...] acional. Presentamos un caso de carcinoma papilar en un quiste del conducto tirogloso tratado en nuestra institución, el cual representa el único caso tratado en nuestro departamento en un período de 17 años. Abstract in english A thyroglossal duct cyst is a congenital anomaly resulting from retention of an epithelial tract between the thyroid and the foramen cecum, at the floor of the pharynx. Papillary carcinoma originating in a thyroglossal duct cyst is a rare event. As far as we know, only 150 cases of thyroglossal duct [...] cyst carcinoma have been reported in the international literature. We present one case of pa-pillary carcinoma arising in a thyroglossal duct cyst treated at our institution. This is the first case managed by our department in seventeen years.

  5. Cáncer papilar primario en quiste del conducto tirogloso. A propósito de un caso

    Scientific Electronic Library Online (English)

    Ysmael, Vegas; José E., Goubaira; Wilfredo, Perfetti; Juan Scarton, López R.; José G., López; Verónica, Mora.

    2005-07-01

    Full Text Available El conducto tirogloso es una anomalía congénita resultado de la retención del tracto epitelial entre la tiroides, el foramen cecum y el piso de la faringe. La aparición de un carcinoma en el quiste del conducto tirogloso es rara, menor del 1 %. Hasta donde sabemos se han publicado 150 casos en la li [...] teratura internacional. Presentamos un caso de carcinoma papilar en un quiste del conducto tirogloso tratado en el Servicio de Cabeza y Cuello del Instituto de Oncología Dr. Miguel Pérez Carreño (centro de referencia nacional), el cual, representa el único caso tratado en nuestro Instituto en el lapso comprendido desde 1986 y el 2003, (17 años). Abstract in english SUMMARY A thyroglossal duct cyst is a congenital anomaly resulting from retention of epithelial tract between the thyroid and its origin, the foramen cecum, at the floor of the pharynx. Carcinoma papillary originating in thyroglossal duct cyst is a rare event, minor of 1 %. As far as we know, only 1 [...] 50 cases of thyroglosal duct cyst carcinoma have been reported in the international literature. We present a case of papillary carcinoma of thyroglossal duct cyst treated in the Head and Neck Surgery Service of the Instituto Oncológico Dr. Miguel Pérez Carreño (national reference center), which, it represents the only case treated in our Institute in the laps included from 1986 and the 2003, (17 years).

  6. Testicular sperm retrieval at the time of bilateral radical orchiectomy

    Directory of Open Access Journals (Sweden)

    Nassir Anmar

    2009-01-01

    Full Text Available A new indication for testicular tissue cryopreservation is discussed here. We evaluate the feasibility of testicular sperm extraction during bilateral orchiectomy for testicular cancer. A 26-year-old man with a history of right orchidopexy presented with primary infertility. Tests revealed left varicocele and oligospermia. He underwent varicocelectomy but was lost to follow-up. Nine months later, he presented with right-sided solid testicular swelling. Ultrasound examination confirmed the finding of possible neoplasm and revealed contralateral intratesticular lesion. Since the patient turned azoospermic, no semen sample could be cryopreserved. Permanent histopathological sections revealed bilateral classical seminomas. On processing the fresh healthy looking specimen, normal-looking viable sperm were obtained. Future attempts at in-vitro fertilization with intracytoplasmic sperm injection should be possible. This method has been described in metachronous testicular cancer, but to our knowledge, we are the first to use it in synchronous bilateral testicular tumors.

  7. Quiste globulomaxilar de localización inusual: Reporte de un caso An unusual case of globulomaxillary cyst: a case report

    Directory of Open Access Journals (Sweden)

    J. Orozco Ariza

    2009-12-01

    Full Text Available El quiste globulomaxilar es un quiste no odontogénico localizado entre el incisivo lateral y canino del maxilar superior, radiográficamente aparece como una lesión radiolúcida unilocular que desplaza las mencionadas piezas dentarias mostrando una imagen de pera invertida característico de la lesión cuya lámina dura es continua y raras veces interrumpida. La valoración clínica radiográfica es importante para plantear en el diagnóstico diferencial la probable presencia del quiste globulomaxilar. La muestra anatomopatológica debe ser remitida íntegramente para su estudio y diagnóstico definitivo demostrando la presencia de tejido epitelial. Se presenta caso clínico de quiste globulomaxilar en un paciente femenino de 19 años de edad localizado entre canino y primer premolar superior izquierdo.Globulomaxillary cyst is a nonodontogenic cyst usually located between maxillary lateral incisor and canine. Radiographic images appears like an unilocular radiolucent lesion that displaced dental teeth showing a invert pear image characteristic of the lesion. X ray and clinical examinations are important to establish the differential diagnosis of globulomaxillary cyst. The hystological examination must be send to its study and definitive diagnoses showing the presence of epithelial tissue. A clinical case of globulomaxillary cyst is presented in a 19 -year- old female patient located between canine and left first premolar maxillary region.

  8. Quiste globulomaxilar de localización inusual: Reporte de un caso / An unusual case of globulomaxillary cyst: a case report

    Scientific Electronic Library Online (English)

    J., Orozco Ariza; A., Díaz Caballero; M., Fonseca Ricaurte.

    2009-12-01

    Full Text Available El quiste globulomaxilar es un quiste no odontogénico localizado entre el incisivo lateral y canino del maxilar superior, radiográficamente aparece como una lesión radiolúcida unilocular que desplaza las mencionadas piezas dentarias mostrando una imagen de pera invertida característico de la lesión [...] cuya lámina dura es continua y raras veces interrumpida. La valoración clínica radiográfica es importante para plantear en el diagnóstico diferencial la probable presencia del quiste globulomaxilar. La muestra anatomopatológica debe ser remitida íntegramente para su estudio y diagnóstico definitivo demostrando la presencia de tejido epitelial. Se presenta caso clínico de quiste globulomaxilar en un paciente femenino de 19 años de edad localizado entre canino y primer premolar superior izquierdo. Abstract in english Globulomaxillary cyst is a nonodontogenic cyst usually located between maxillary lateral incisor and canine. Radiographic images appears like an unilocular radiolucent lesion that displaced dental teeth showing a invert pear image characteristic of the lesion. X ray and clinical examinations are imp [...] ortant to establish the differential diagnosis of globulomaxillary cyst. The hystological examination must be send to its study and definitive diagnoses showing the presence of epithelial tissue. A clinical case of globulomaxillary cyst is presented in a 19 -year- old female patient located between canine and left first premolar maxillary region.

  9. Testicular cancer trends as 'whistle blowers' of testicular developmental problems in populations

    DEFF Research Database (Denmark)

    Skakkebaek, N E; Rajpert-De Meyts, E

    2007-01-01

    Recently a worldwide rise in the incidence of testicular germ cell cancer (TGCC) has been repeatedly reported. The changing disease pattern may signal that other testicular problems may also be increasing. We have reviewed recent research progress, in particular evidence gathered in the Nordic countries, which shows strong associations between testicular cancer, undescended testis, hypospadias, poor testicular development and function, and male infertility. These studies have led us to suggest the existence of a testicular dysgenesis syndrome (TDS), of which TGCC, undescended testis, hypospadias/disorders of sex differentiation and male fertility problems may be symptoms with varying penetration. In spite of their fetal origin, most of the TDS symptoms, including TGCC and poor semen quality, can only be diagnosed in adulthood. Data from a Danish-Finnish research collaboration strongly suggest that trends in TGCC rates of a population may be 'whistle blowers' of other reproductive health problems. As cancer registries are often of excellent quality - in contrast to registries for congenital abnormalities - health authorities should consider an increase in TGCC as a warning that other reproductive health problems may also be rising.

  10. Testicular Parameters and Morphological Characteristics of Testicular and Epididymal Spermatozoa of White Fulani Bulls in Nigeria Parámetros Testiculares y Características Morfológicas de los Espermatozoides Testicular y Epididimal de Toros Fulani Blancos en Nigeria

    OpenAIRE

    Matthew Olugbenga Oyeyemi; Temilade Babalola Eunice

    2006-01-01

    Testicular parameters and morphological characteristics of testicular and epididymal spermatozoa of white Fulani bulls were study using twenty testicles. The objective was to study the normal testicular parameter and morphological changes during epididymal transit in the epididymis of white Fulani bulls. It was observed that there was reduction in the proportion of spermatozoa carrying the proximal cytoplasmic droplet (PCD) along the epididymis as spermatozoa mature. There were more narrow he...

  11. Linfoma no Hodgkin testicular con compromiso de tejidos blandos

    OpenAIRE

    Bernal. P.; Duarte M.; Ucros. G.

    2008-01-01

    El compromiso testicular por linfoma es una manifestación extranodal de la enfermedad, manifestación inicial de una enfermedad nodal oculta o manifestación tardía de linfoma nodal diseminado. Corresponde al 5% de todos los tumores testiculares y es la neoplasia mas común del testículo en los pacientes mayores de 50 anos. [1]., sin embargo el linfoma primario de testículo es extremadamente raro [5]. corresponde al 1% de los LNH [3]. La mayoría de los linfomas testiculares son LNH B difuso de c...

  12. Bilateral and synchronic seminomatous testicular neoplasia

    Scientific Electronic Library Online (English)

    Ademar, Schmitz.

    2003-08-01

    Full Text Available Testicular neoplasia is rare, especially when it is bilateral, and even more when it is synchronic, with its incidence being only 0.17% of germinative tumors of testicles. We present here the case of a male, 32-year old patient, without children. Patient underwent a bilateral radical orchiectomy, fo [...] llowing previous sperm harvest, in a sperm bank. Surgery was performed in 2 stages, with a 12-day interval, with implantation of a silicone testicular prosthesis. The result of anatomicopathological examination revealed bilateral classical seminoma, pT2 on the right side andT1 on the left. He was submitted to bilateral complementary radiotherapy, with 2,500 cGy on each side. Patient had a good outcome from a medical and oncologic perspective, but a follow-up with psychotherapy was needed.

  13. [Relationship between phthalates and testicular dysgenesis syndrome].

    Science.gov (United States)

    Chen, Guo-Rong; Dong, Lei; Ge, Ren-Shan; Hardy, Matthew P

    2007-03-01

    Recent epidemiological evidence demonstrates that boys born to women exposed to phthalates during pregnancy have an increased incidence of cryptorchidism, hypospadias, testicular cancer and spermatogenic dysfunction, which are collectively referred to as testicular dysgenesis syndrome (TDS). TDS may be attributed to the dysfunction of Leydig cells and Sertoli cells during their differentiation after exposure to phthalates in utero. Fox example, Leydig cell functions are significantly affected by phthalates, leading to the decrease of two Leydig cell products--insulin-like growth factor 3 (INSL3) and testosterone, which are critical factors for testis descent. The disorientation of Leydig cells and Sertoli cells in the adult testis may be the cause of spermatogenic dysfunction. PMID:17393778

  14. Carcinoma epidermoide de la conjuntiva, su posible asociación con el papilomavirus humano Epidermoid carcinoma of the conjunctiva, its possible association with human papillomavirus

    Directory of Open Access Journals (Sweden)

    María de los Ángeles Rios Hernández

    2004-08-01

    Full Text Available El carcinoma epidermoide de células escamosas de la conjuntiva ocupa el segundo lugar en frecuencia de los tumores malignos oculares. Este tumor puede tener una evolución letal si no es diagnosticado y tratado en etapas tempranas. Recientes reportes de la literatura, muestran la presencia del papilomavirus humano 16 (PVH 16 en displasias epiteliales conjuntivales y carcinoma escamoso, este virus puede desempeñar un papel importante en el desarrollo de lesiones benignas y malignas de la conjuntiva. Sin embargo, la información es escasa y contradictoria, por lo que es interés nuestro estudiar un grupo de ellas. Se determinó la presencia de los PVH 16 y 18 por la técnica de PCR, se halló la presencia de los tipos 16 (66,6 % y 18 (66,6 % en lesiones premalignas mientras que en las malignas fue del 50 % para el tipo 16 y del 25 % para el tipo 18. Se demostró la existencia de infección viral por papiloma en lesiones de la conjuntiva, con una mayor carga viral en las lesiones premalignas lo que pudiera ser un factor necesario para la transformación maligna en esta localización.The epidermoid squamous cell carcinoma of the conjunctiva occupies the second place in frequency among the occular malignant tumors. This tumor may have a lethal evolution if it is not diagnosed and treated early. Recent reports of literature show the presence of human papillomavirus 16 (HPV in conjunctival epithelial displasias and squamous cell carcinoma. This virus may play an important role in the development of bening and malignant lesions of the conjunctiva. However, the information is scarce and contradictory and that´s why we are interested in studying a group of them. The presence of HPV16 and 18 was determined by using the PCR technique. Types 16 (66.6 % and 18 (66.6 % were found in premalignant lesions, whereas 50% of type 16 and 25 % of type 18 were observed in malignant lesions. It was proved the existance of viral infection due to papilloma in conjunctiva lesions, with a higher viral burden in the premalignant lesions, which may be a necessary factor for the malignant transformation in this localization.

  15. Testicular Compromise due to Inguinal Hernia

    OpenAIRE

    Morgan Eutermoser; Kristen Nordenholz

    2012-01-01

    A 34-year-old male presented to the emergency department with a 3-hour complaint of pain in the rightlower quadrant and right testicle. He stated that his pain began suddenly while standing at work. Onphysical examination, he had a small, firm, unreducible bulge in his right inguinal canal and an enlargedright scrotum. The patient was placed in trendelenburg position; intravenous fentanyl, valium, anddilaudid were administered; and surgery consult was obtained. A testicular ultrasonogram (Fig...

  16. Testicular tumors - clinical aspects and therapy

    International Nuclear Information System (INIS)

    In this study the author reports about classification, clinical experience, therapy and therapeutic results of testicular tumors on the basis of results given in literature and of own investigations performed at the Clinic and Policlinic for Radiotherapy at Wuerzburg. In total, 97 patients with testicular tumors were examined and their cases analysed. These patients had received radiotherapy between January 1, 1962 and December 31, 1979. The difficulties with the intended classification of testicular tumors and the advantages and disadvantages of the individual nomenclatures are described. Consideration of the affected age-groups showed that this disease concerns mainly younger males with a high life expectancy. The study depicts the relatively discrete symptoms and signs and the difficulties connected with clinical diagnosis. A more generous indication for the exposition of the testicles is demanded. Also the lymphatic drainage of the testicular region, the resulting paths of metastatic spread and the difficulties connected with the lymphographic detection of metastases are described. There are three therapeutic measures: surgical intervention, radiotherapy and cytostatic treatment. With seminomas mandatory semitestectomy and radiotherapy will suffice; with other affections than seminomas, semitestectomy shall be followed by a combined therapy comprising removal of lymphatic nodes and cytostatic treatment and not so much radiotherapy. The results of treatment given in literature are compared with the own results. This comparison revealed good success with treatment of seminomas. With non-seminomal affections exclusive radiotherapy appears to be insufficient. Therefore a combined therapy is postulated, which must be rendered possible by a good interdisciplinary cooperation of pathologists, urologists and radiologists. (orig.)

  17. Testicular Histomorphometric Evaluation of Zebu Bull Breeds

    Scientific Electronic Library Online (English)

    Paulo Antônio Terrabuio, Andreussi; Deiler Sampaio, Costa; Fábio José Carvalho, Faria; Carlos Antônio Carvalho, Fernandes; Marcelo Diniz, Santos; Juliana Correa Borges, Silva.

    2014-12-01

    Full Text Available The objective of this study was to evaluate the quantitative histology and testicular biometrics in zebu bulls of different breeds. Testicular fragments of Nelore (n=10), Polled Nelore (n=6), Gir (n=5), Guzerat (n=5) and Tabapuã bulls (n=5) were used. The fragments were perfusion-fixed in Karnovsky [...] solution, embedded in glycol methacrylate and stained with toluidine blue-1% sodium borate. The Nelore animals had a higher tubular volumetric proportion (85.2%) and greater height of the seminiferous epithelium (73.2 µm) than the Gir, Guzerat and Tabapuã breeds. The Nelore animals also had a higher volumetric proportion of Leydig cells (5.2%) than the Guzerat and Tabapuã breeds. There was no significant difference for any of these parameters between the Nelore and Polled Nelore breeds. The gonadosomatic index, seminiferous tubule diameter, cross-sectional area of the seminiferous tubule and tubule length (total length and length per gram of testicular parenchyma) did not vary among the breeds studied. The morphometric parameters evaluated suggested that the genetic selection applied to the Nelore and Polled Nelore breeds improved the efficiency of spermatogenesis in these breeders.

  18. Tumor desmoide mesentérico simulando una recidiva de cáncer testicular / Mesenteric desmoid tumor mimicking a testicular cancer recurrence

    Scientific Electronic Library Online (English)

    Francisco Javier, Pérez García; Jesús, Pinto Blazquez; Juan Javier, Rodríguez Martínez; Ricardo, Gutiérrez García; José Ignacio, Jorge Barreiro; Julio, Velasco Alonso.

    2007-08-01

    Full Text Available Objetivo: Presentar un caso de un tumor desmoide en un paciente tratado de un seminoma testicular que simulaba una recidiva del tumor testicular. Método: Presentamos el caso de un paciente de 41 años, tratado de un seminoma testicular 26 meses antes, mediante extirpación de una masa testicular retro [...] peritoneal y quimioterapia, que presenta en el seguimiento, una masa abdominal mesentérica que se etiquetó clínicamente de recidiva de seminoma. Resultado: Histológicamente se informa de tumor desmoide mesentérico. Se hace diagnóstico diferencial con un tumor de estroma gastrointestinal mediante el estudio inmunohistoquímico. Conclusiones: El tumor desmoide es un tumor raro. Se han descrito pocos casos en pacientes afectos previamente de tumor testicular. Debe incluirse en el diagnóstico diferencial de las recidivas por tumor testicular. Abstract in english Objective: Report of one case of desmoid tumor in a patient who had been treated of a testicular seminoma 26 months before, with excision of a retroperitoneal mass and chemotherapy. On follow-up he presented with a mesenteric abdominal mass which was clinically labeleled as a recurrence of the semin [...] oma. Results: Histologically it was reported as a mesenteric desmoid tumor. Differential diagnosis with gastrointestinal stromal tumor was performed with immunohistochemical studies. Conclusions: Desmoid tumor is rare. There are few cases reported in patients with history of previous testicular tumor. It should be included in the differential diagnosis of testicular tumor recurrences.

  19. Variaciones anatómicas bilaterales de vasos renales y testiculares / Bilateral anatomical variations of renal and testicular vessels

    Scientific Electronic Library Online (English)

    HUMBERTO, FERREIRA ARQUEZ.

    2014-12-01

    Full Text Available Normalmente las arterias testiculares surgen de la aorta abdominal, aunque hay reportes acerca de variaciones en su origen. También es un hallazgo común dos arterias renales (derecha e izquierda) derivadas de la aorta abdominal que suministran irrigación al respectivo riñón de cada lado, y actualmen [...] te la literatura reporta gran variabilidad en el número de arterias renales. Durante una disección de rutina en un cadáver masculino de 65 años de edad se encontraron múltiples variaciones anatómicas bilaterales de vasos testiculares y renales. Las variaciones encontradas fueron: presencia bilateral de tres arterias renales y tres venas renales, vena renal izquierda retro-aórtica, terminación de la vena frénica inferior izquierda en la vena renal izquierda, doble arteria testicular izquierda y doble arteria testicular derecha, todas originándose desde arterias renales accesorias. Las variaciones descritas aquí son únicas, no conocidas, ya que es el primer caso reportado hasta ahora en la literatura disponible y proporcionan una información significativa a radiólogos, endocrinólogos, especialistas en fertilidad, urólogos y cirujanos, en la determinación de la viabilidad de intervenciones quirúrgicas libres de complicación en esta región, así como el manejo postoperatorio Abstract in english Testicular arteries normally arise from the abdominal aorta. There are reports about of variations in the origin. It is also a common finding two (right and left) derived renal arteries of the abdominal aorta to the respective supplying irrigation kidney from each side, current literature report gre [...] at variability in the number of renal arteries. Multiple anatomical variations bilateral of testicular vessels and renal were found during routine dissection in a 65-year-old male cadaver. The variations found were: bilateral presence of three renal arteries and three renal veins, left renal vein retro-aortic, termination of the left inferior phrenic vein into the left renal vein, double left testicular artery and double right testicular artery all originating from accessory renal arteries. The variations described here are unique is not known since it is the first case reported so far in the available literature and provide significant informations to radiologists, endocrinologists, fertility specialists, urologists and surgeons, in determining the feasibility of complication-free surgical interventions in this region as well as the post-operative management

  20. Quiste endodérmico supratentorial: caso clínico y revisión de la literatura / Supratentorial endodermal cyst: Case report

    Scientific Electronic Library Online (English)

    J.M., Garbizu; O., Mateo-Sierra; B., Iza; F., Ruiz-Juretschke; J.M., Pérez-Calvo.

    2009-08-01

    Full Text Available Los quistes endodérmicos que afectan al sistema nervioso central son lesiones expansivas muy poco frecuentes que se sitúan con mayor frecuencia a nivel espinal. Existen poco casos de localización intracraneal descritos en la literatura, la mayoría de ellos en la fosa posterior. Su etiopatogenia perm [...] anece aún desconocida. Presentamos el caso de un varón de 62 años que debuta con un cuadro de desorientación y comportamiento desinhibido tras sufrir un traumatismo craneoencefálico como consecuencia de un accidente de tráfico. En la TC craneal realizada de urgencia se objetiva una lesión quística frontal izquierda de gran tamaño con importante desplazamiento de línea media. Se punciona y evacua el contenido del quiste obteniéndose un líquido opalino rico en proteínas y elementos celulares no identificados. La RMN nos confirma los hallazgos radiológicos previos. El paciente es intervenido de forma reglada mediante craneotomía, evacuación completa del contenido y extirpación de las paredes de la lesión. El estudio anatomopatológico resulta ser compatible con el diagnóstico de quiste endodérmico. Se han descrito casos de evolución agresiva con diseminación y recidiva tras manipulación quirúrgica de la lesión; por lo tanto, el tratamiento debe consistir en la extirpación completa de la misma. Para ello será necesario realizar el diagnóstico diferencial con otras lesiones quísticas intracraneales con el fin de adecuar el tratamiento a cada caso. Abstract in english Endodermal cysts (EC) of the central nervous system are very uncommon lesions predominantly located in the spinal canal. Although rare, intracranial EC have been mainly described in the posterior fossa, with the supratentorial location considered exceptional. Apart from the low frequency of these le [...] sions, their pathoembriology still remais unknown. We report a patient with a huge frontal EC and review the literature. A 62-year-old man presented with abnormal behaviour, disorientation and decreased level of consciousness after moderate head injury. Initial cranial CT scan revealed a large cyst in the left frontal region with marked midline shift. Emergency puncture and decompression of the cyst demonstrated a milky fluid with high protein levels. Cranial MRI after patient improvement confirmed the existence of the cystic lesion with less mass effect. Delayed surgery was performed with craniotomy and total removal of the cyst. Pathological examination confirmed the presence of a typical EC. Patient made a complete recovery on follow-up with no recurrence on postoperative MRIs. Differential diagnosis of EC based on radiological data is quite difficult. As aggresive behaviour of this condition has been described following incomplete resections, the treatment of choice is a radical removal of the cyst in one or two stages depending on patient clinical condition.

  1. Choledochal cyst. A case presentation Quiste de colédoco. Presentación de un caso

    Directory of Open Access Journals (Sweden)

    Daniel Olivera Fajardo

    2012-06-01

    Full Text Available

    Congenital dilatation of the bile duct and its incidence is a rare condition reported in one in 100 000 to 150 000 newborns. Current concern about the evolution of this process is that a cholangiocarcinoma might appear. The case of a female teenager of urban origin, who attended her health area polyclinic, because of a moderate 5 months pain in her high epigastrium and in her upper right abdomen is presented. The pain appeared always after eating accompanied by vomiting and it was self-relieved. An abdominal ultrasound indicated by the patient’s family doctor showed a liver cyst. It was decided to perform an abdominal computed tomography. Through this test a cyst at the pancreatic head was found. The patient was admitted in the emergency room of the ‘’Gustavo Aldereguía Lima’’ Hospital of Cienfuegos, where she was evaluated by the physicians in the Surgery Department. It was decided to treat her surgically. Anatomopathologic results showed chronic cholecystitis, choledochal cyst and nonspecific chronic inflammation.

    La dilatación congénita de las vías biliares y su incidencia es rara, se presenta un caso cada 100 000 a 150 000 nacimientos. La preocupación actual respecto a la evolución de este proceso, es que origine un colangiocarcinoma. Se presenta el caso de una adolescente de procedencia urbana, que acudió a  cuerpo de guardia de su área de salud, refiriendo que desde hacía aproximadamente 5 meses presentaba dolor  moderado en ¨la boca¨ del estómago y en la región superior derecha del abdomen que aparecía siempre después de ingerir alimentos, se aliviaba por sí solo y se acompañaba de vómitos. Su médico de familia  indicó ultrasonido abdominal, donde se observó un quiste en el hígado. Fue  trasladada al Cuerpo de Guardia del Hospital General Universitario Dr. Gustavo Aldereguía Lima, de Cienfuegos, donde fue valorada por el Servicio de Cirugía. Se decidió la realización de  tomografÍa axial computarizada de abdomen en la que se observó un quiste a nivel de la cabeza del páncreas. Se aplicó tratamiento quirúrgico. Los resultados anatomopatológicos mostraron colecistitis crónica, quiste de colédoco e inflamación crónica inespecífica.

  2. Prognostic role of p53 protein expression in epidermoid carcinoma of the anal canal

    International Nuclear Information System (INIS)

    Purpose: To assess the prognostic significance of p53 protein expression in patients with primary epidermoid carcinoma of the anal canal managed by radiation therapy (XRT), 5-fluorouracil (5-FU), and mitomycin C (MMC). Methods and Materials: From January 1991 to December 1993, 58 consecutive patients with primary epidermoid carcinoma of the anal canal were treated in a prospectively designed protocol of XRT (24 Gy/12--3((1)/(2)) wk split--28 Gy/14) and concurrent 5-FU (1000 mg/m2/day 1-4) and MMC (10 mg/m2 day 1) of each cycle of XRT. Paraffin-embedded tumor samples were unavailable in 9 patients, leaving 49 patients in the study. Expression of p53 protein was studied using immunohistochemistry and quantified as percent tumor nuclei showing positive staining. Actuarial survival and disease-free survival (DFS) rates were estimated by the Kaplan-Meier method, and compared using the log-rank test. A Cox proportional hazard model was used for the multivariable analysis. Results: There were 6 T1, 26 T2, 7 T3, and 10 T4 lesions. Primary tumor sizes ranged from 1-15 cm with a median of 4 cm. There were 6 patients with nodal metastases. Median follow-up was 4.5 years. Positive nuclear immunostaining for p53 was observed in 40 of 49 patients. The median percent positive staining was 5%, with 13, 9, and 18 patients showing staining in <5%, 5 to <10%, and 10-50% of tumor nuclei respectively. There was no correlation of percent p53 staining with gender, age, tumor stage, size, or histology. Local, regional, and distant failures were observed in 12, 2, and 2 patients respectively. The 5-yr survival and DFS were 84% and 64% respectively. In univariate analysis, the only prognostic variable for survival was gender. For DFS, advanced T category and large tumor size were predictive of poor DFS. In multivariate analysis, poor DFS was associated with high T category (p = 0.0008), basaloid histology (p = 0.001), male gender (p = 0.002), and increasing percent of p53 protein expression (p 0.01). Conclusions: It is concluded that expression for p53 protein is present in a high percentage of patients with epidermoid carcinoma of the anal canal. For patients managed with combined XRT, 5-FU, and MMC, percent p53 protein expression is of prognostic value for DFS independent of other clinical factors such as T category, gender, and histology

  3. Tumores dermóides e epidermóides intra-espinhas Intraspinal epidermoid and dermoid tumours

    Directory of Open Access Journals (Sweden)

    Oscar Fontenelle Filho

    1971-03-01

    Full Text Available São relatados dois casos de tumores epidermóides e um de tumor dermóide, todos intrarraquianos. Este último era de localização epidural ao nível da coluna torácica (caso 3; os dois tumores epidermóides situavam-se na coluna tóraco-lombar (caso 1 e lombar (caso 2, respectivamente, sendo o primeiro intramedular e o segundo intradural. Em dois casos (casos 2 e 3 os tumores associavam-se a fístula dérmica congênita. Um paciente (caso 3 foi operado aos dois meses de idade; a descoberta do tumor deveu-se à realização da raquimanometria que revelou bloqueio, apesar do paciente não apresentar qualquer sinal neurológico de compressão medular. Os autores são de opinião que, em presença de fístula dérmica congênita ao nível da coluna vertebral, principalmente quando localizada acima do segmento lombosacro, deve-se sempre suspeitar da possibilidade do tumor epidermóide ou dermóide intrarraquiano, mesmo na ausência de sinais neurológicos. A combinação de sintomas neurológicos de longa duração, a evidência radiológica de erosão e alargamento do canal raquiano e a história de fístula dérmica congênita proporcionaram o diagnóstico pré-operatório correto no caso 2.Two cases of epidermoids and one case of dermoid intraspinal tumours are reported. The last case was located at thoracic level (T7 (case 3 and was epidural in localization. The two epidermoids tumours were located at the thoracic-lumbar (case 1 and lumbar (case 2 level, respectively; the first was intramedullary and the second subdural in localization. In two (cases 2 and 3 there was associated communicating pilonidal sinuses. One of the patients (case 3 was operated within the second month of age. The early discovery of the tumour in this patient was made through a lumbar raquimanometry that disclosed a complete subarachnoid block. In spite of this the patient did not presented any neurological symptoms. The authors are of opinion that in presence of a dermal fistula higher to lumbo-sacral spinal segment one must have in mind the possibility of intraspinal epidermoid or dermoid tumour, even in absence of neurological symptoms. The combination of long term clinical symptoms, radiographic evidence of pressure erosion, enlargement of the spinal canal and pilonidal sinus led to the correct preoperative diagnosis in case 2.

  4. Tumores dermóides e epidermóides intra-espinhas / Intraspinal epidermoid and dermoid tumours

    Scientific Electronic Library Online (English)

    Oscar, Fontenelle Filho; Francisco, Duarte.

    1971-03-01

    Full Text Available São relatados dois casos de tumores epidermóides e um de tumor dermóide, todos intrarraquianos. Este último era de localização epidural ao nível da coluna torácica (caso 3); os dois tumores epidermóides situavam-se na coluna tóraco-lombar (caso 1) e lombar (caso 2), respectivamente, sendo o primeiro [...] intramedular e o segundo intradural. Em dois casos (casos 2 e 3) os tumores associavam-se a fístula dérmica congênita. Um paciente (caso 3) foi operado aos dois meses de idade; a descoberta do tumor deveu-se à realização da raquimanometria que revelou bloqueio, apesar do paciente não apresentar qualquer sinal neurológico de compressão medular. Os autores são de opinião que, em presença de fístula dérmica congênita ao nível da coluna vertebral, principalmente quando localizada acima do segmento lombosacro, deve-se sempre suspeitar da possibilidade do tumor epidermóide ou dermóide intrarraquiano, mesmo na ausência de sinais neurológicos. A combinação de sintomas neurológicos de longa duração, a evidência radiológica de erosão e alargamento do canal raquiano e a história de fístula dérmica congênita proporcionaram o diagnóstico pré-operatório correto no caso 2. Abstract in english Two cases of epidermoids and one case of dermoid intraspinal tumours are reported. The last case was located at thoracic level (T7) (case 3) and was epidural in localization. The two epidermoids tumours were located at the thoracic-lumbar (case 1) and lumbar (case 2) level, respectively; the first w [...] as intramedullary and the second subdural in localization. In two (cases 2 and 3) there was associated communicating pilonidal sinuses. One of the patients (case 3) was operated within the second month of age. The early discovery of the tumour in this patient was made through a lumbar raquimanometry that disclosed a complete subarachnoid block. In spite of this the patient did not presented any neurological symptoms. The authors are of opinion that in presence of a dermal fistula higher to lumbo-sacral spinal segment one must have in mind the possibility of intraspinal epidermoid or dermoid tumour, even in absence of neurological symptoms. The combination of long term clinical symptoms, radiographic evidence of pressure erosion, enlargement of the spinal canal and pilonidal sinus led to the correct preoperative diagnosis in case 2.

  5. Tratamiento quirúrgico conservador en un caso de quiste de iris postraumático Conservative surgical management of a post-traumatic iris cyst

    OpenAIRE

    M. Moreno-López; C. Arruabarrena; A. Regueras; Noval, S

    2007-01-01

    Caso clínico: Varón de 32 años aquejado de pérdida visual en ojo derecho (OD) secundario a un quiste que ocupa la mitad de la cámara anterior, diagnosticado clínicamente de quiste secundario epitelial de iris. Tres años antes había sufrido un traumatismo penetrante. Se realiza aspiración con aguja, viscodisección y fotocoagulación ab externo, logrando una rápida recuperación visual sin secuelas funcionales ni anatómicas. A los seis meses la agudeza visual permanece estable sin recidiva de la ...

  6. Estudio de la fertilidad y viabilidad de quistes hidatídicos bovinos en Chile STUDY OF THE FERTILITY AND VIABILITY OF BOVINE HIDATID CYSTS IN CHILE

    OpenAIRE

    JUAN PABLO MUÑOZ; GEROLD SIEVERS

    2005-01-01

    Durante el año 1997, se muestrearon por conveniencia 4.709 bovinos de un total de 83.691 animales faenados en la Planta Faenadora de Carnes Lo Valledor, Región Metropolitana, Chile. Se registró su procedencia, sexo y categoría y en los animales positivos a hidatidosis se constató la ubicación visceral y el tamaño de los quistes. En el laboratorio se verificó la fertilidad (presencia o ausencia de protoescólices) de los quistes obtenidos y su viabilidad mediante la tinción con azul de Trypán. ...

  7. Estudio de la fertilidad y viabilidad de quistes hidatídicos ovinos / Fertility and viability study of hydatid cysts from ovine

    Scientific Electronic Library Online (English)

    José Luis, García Llamazares; Ana Isabel, Álvarez de Felipe; Pedro Angel, Redondo Cardeña; Julio Gabriel, Prieto Fernández.

    1997-09-01

    Full Text Available FUNDAMENTO: La finalidad de este trabajo es analizar la fertilidad de los quistes hidatídicos de origen ovino, especie de gran interés epidemiológico en la hidatidosis, y la adecuación del gerbillo (Meriones unguiculatus) como modelo experimental para el estudio "in vivo" de dicha hidatidosis, fase [...] preliminar de posteriores estudios terapeúticos. MÉTODOS: Se ha realizado un estudio de la fertilidad y viabilidad de quistes hidatídicos procedentes de pulmones e hígados de ganado ovino de Castilla y León a través del examen y evaluación de una serie de parámetros entre los que figura la producción de una hidatidosis secundaria experimental en animales de laboratorio. RESULTADOS: El índice quístico total obtenido fue de 8,57 quistes por ovino infestado (5,97 quistes por pulmón infestado y 5,57 quistes por hígado infestado). El porcentaje de fertilidad obtenido en los quistes hidatídicos de origen ovino que contenían protoescólex viables "in vitro" fue del 43,97% (43,02% en los quistes pulmonares y 46,16% en los quistes hepáticos). La viabilidad "in vivo" de los protoescólex seleccionados se puso de manifiesto al producirse en el 100% de los gerbillos infectados una hidatidosis secundaria experimental. CONCLUSIONES: Se destaca la validez de los criterios utilizados para estudiar la viabilidad "in vitro" de los protoescólex procedentes de quistes hidatídicos de origen ovino. La hidatidosis secundaria producida en gerbillos nos conduce a considerarlos como especie de experimentación adecuada para la investigación "in vivo" de la hidatidosis de origen ovino. Abstract in english BACKGROUND: The purpose of this work is to analyze the fertility of the hydatid cysts from ovine, animal species of great epidemiological interest in the hydatid disease, and the ability of the gerbil (Meriones unguiculatus) as model experimental for the study "in vivo" of this hidatyd disease as pr [...] eliminary phase of therapeutic studies. METHODS: It has been carried out a study of the fertility and viability of hydatid cysts from lungs and livers of ovine from Castilla and Leon by examination and evaluation of parameters among these is the production of a secondary hydatid disease in laboratory animals. RESULTS: The total cystic index was 8.57 cysts by infested ovine (5.97 cysts by infested lung and 5.57 cysts by infested liver). The fertility percentage obtained in hydatid cysts from ovine with "in vitro" viables protoescoleces was 43.97% being 43.02% in pulmonary cysts and 46.16% in hepatic cysts. The viability of protoscoleces was demonstrated by production of a secondary hydatid disease in 100% of gerbils infested. CONCLUSIONS: It is emphasized the validity of the criteria used to study the viability "in vitro" of the protoescoleces from hydatid cysts of origin ovine. The secondary hydatid produced in gerbils leads us to consider them as experimental animal for investigation "in vivo" of hydatid disease of origin ovine.

  8. Quiste dentígero que causa deformación facial en un niño. Presentación de un caso

    Directory of Open Access Journals (Sweden)

    Juan Carlos Quintana Díaz

    2012-09-01

    Full Text Available Se presenta un caso interesante de un niño de 13 años que acude a la consulta de Cirugía Máxilofacial por presentar asimetría facial y bucal, además de obstrucción nasal del lado de la deformidad. Después de realizar exámenes de laboratorio y radiográficos se lleva sala de cirugía para realizar la exéresis del canino superior derecho retenido, enuclear la extensa área radiolucida a los rayos X y se reconstruye el defecto óseo residual con Hidroxiapatita en gránulos HAP-200, posteriormente se realiza estudio histopatológico. El diagnóstico definitivo corroboró el presuntivo (quiste dentígero. El paciente evolucionó de forma excelente desapareciendo la deformidad facial y los demás síntomas preoperatorios. El examen radiográfico post-operatorio mostró una excelente reconstrucción y osteo-integración del material empleado.

  9. CARCINOMA PAPILAR DE TIROIDES EN QUISTE DEL CONDUCTO TIROGLOSO / Thyroglossal duct cyst with papillary carcinoma

    Scientific Electronic Library Online (English)

    Patricio, Cabané T; Patricio, Gac E; Francisco, Rodríguez M; Carolina, Morales O; Juan, Aldana L; Ignacio, Boza T; Cristina, Fernández E; José, Amat V.

    2015-04-01

    Full Text Available Introducción: En alrededor de 1-2% de los casos de quiste tirogloso pueden existir cambios neoplásicos, en su mayoría corresponden a carcinoma papilar de tiroides (75-85%). El objetivo de este trabajo es presentar 9 casos de carcinoma papilar de tiroides en quiste del conducto tirogloso, en cuanto a [...] su forma de presentación y manejo. Material y Método: Se registraron en forma retrospectiva datos de pacientes con diagnóstico de carcinoma papilar de tiroides en quiste del conducto tirogloso atendidos en el Hospital Clínico de la Universidad de Chile entre 1999-2014. Resultados: De 142 casos de pacientes operados por quiste del conducto tirogloso, se registraron 9 casos de cáncer papilar (6,34%). El promedio de edad de los pacientes fue de 32 años. El diámetro promedio de la lesión fue de 4,4 cm (DS 2,2 cm). Del total, 8 pacientes fueron sometidos a tiroidectomía total, se diagnosticó cáncer de tiroides en 3 de ellos, en 6 se asoció tratamiento con radioyodo. En sólo 1 paciente se realizó una disección linfonodal. El tiempo promedio de seguimiento fue de 85 meses; a la fecha la serie no ha presentado recurrencia ni mortalidad. Conclusiones: Si bien el manejo más seguro a largo plazo es la cirugía de Sistrunk, asociado a una tiroidectomía y eventual radioyodo, la resolución quirúrgica con tiroidectomía asociada debe ser considerada cuando la morbilidad no sea mayor que el beneficio teórico. Abstract in english Introduction: In about 1-2% of cases of thyroglossal cyst may be neoplastic changes, mostly correspond to papillary thyroid carcinoma (75-85%). The aim of this paper is to present 9 cases of papillary thyroid carcinoma in thyroglossal duct cyst. Materials and Methods: Data were recorded retrospectiv [...] ely from patients diagnosed with papillary thyroid carcinoma in thyroglossal duct cyst treated at Hospital Clinico Universidad de Chile between 1999-2014. Results: From 142 cases operated for thyroglossal duct cyst, 9 cases of papillary cancer (6.34%) were recorded. The average age was 32 years. The average diameter of the lesion was 4.4 cm (SD 2.2 cm). 8 patients underwent total thyroidectomy; a simultaneous thyroid cancer was diagnosed in 3 of them. In 6 cases was added iodine therapy. In only one patient a lymph nodal dissection was performed. We do not observe any surgical complication. A solid component in preoperative ultrasonographic study is suspicious of malignancy. The average follow-up time was 85 months. There is no recurrence or mortality in this group of patients. Conclusions: Although the safest long-term management is Sistrunk surgery associated with thyroidectomy and radioiodine in selected cases, these patients must be evaluated by a multidisciplinary group and thyroidectomy should be considered in high surgical volume center, in order to minimize complications.

  10. A simple vitrification method for cryobanking avian testicular tissue

    Science.gov (United States)

    Cryopreservation of testicular tissue is a promising method of preserving male reproductive potential for avian species. This study was conducted to assess whether a vitrification method can be used to preserve avian testicular tissue, using the Japanese quail (Coturnix japonica) as a model. A sim...

  11. [Prognostic factors in megavolt radiotherapy of central epidermoid carcinoma of the lung].

    Science.gov (United States)

    Zhakov, I G

    1983-05-01

    Radical program radiotherapy was provided to 403 patients with inoperable central epidermoid lung carcinoma that does not extend beyond one half of the thoracic cavity. Long-term therapeutic results depend on numerous factors the interrelationships of which cannot be revealed without present-day methods of data analysis. The use of computers (a method of parameter grouping and semi-automatic classification--"teaching without a teacher") made it possible before treatment to approach the level of group prognosis by symptoms; taking into account the time course of symptoms in the process of radiation therapy and after its termination--to reach the level of individual prognosis for 22% of the patients. PMID:6406784

  12. Correlación clínico-citohistológica de los quistes congénitos cervicales / Clinical-cytohistological correlation of cervicofacial congenital cysts

    Scientific Electronic Library Online (English)

    L.D., Medina Vega; E., Márquez Rancaño; J., Concepción Guzmán; R., Rodríguez Jiménez; J., Martín Pino.

    2004-02-01

    Full Text Available Objetivo: Determinar la efectividad de los diagnósticos clínico y citológico en los quistes congénitos cervicofaciales. Método: Se realizó un estudio retrospectivo de los pacientes con diagnóstico clínico, citológico y/o histológico de quiste tirogloso, branquial y dermoide, atendidos en el Hospital [...] Universitario «Arnaldo Milián Castro», durante cinco años. Se calculó la sensibilidad, especificidad y seguridad del diagnóstico clínico y la biopsia por aspiración con aguja fina (FNAC) para cada quiste. Resultado: La seguridad del diagnóstico clínico fue de 94,1%, 92,2% y 98% para los quistes tirogloso branquial y dermoide respectivamente. Encontramos mayor tendencia al error clínico en los quistes branquiales, donde las confusiones más frecuentes se presentan con linfoadenopatías inflamatorias. La seguridad de la biopsia por aspiración con aguja fina fue de 96,1% y 94,1% para los quistes tirogloso y branquial respectivamente. Conclusiones: El diagnóstico clínico no es suficiente en ocasiones, por lo que es preciso recurrir a medios diagnósticos complementarios, como la biopsia por aspiración con aguja fina; sin embargo esta prueba no es 100% segura. Abstract in english Objective: To determine the effectiveness of clinical and cytological diagnosis in congenital cysts located in head and neck. Method: We were carried out a retrospective study of patients with clinical, cytological or histological diagnosis of thyroglossal, branchial and dermoid cyst, assisted in th [...] e University Hospital Arnaldo Milián Castro", during five years. It was calculated the sensibility, specificity and security of the clinical diagnosis and the Fine Needle Aspiration Biopsy for each cyst. Result: The security of the clinical diagnosis it was respectively of 94,1%, 92,2% and 98% for the thyroglossal, branchial and dermoid cysts. We find bigger tendency to the clinical error in branchial cysts, where the most frequent confusions are presented with inflammatory linfoadenopathy. The security of the Fine Needle Aspiration Biopsy was of 96,1% and 94,1% for the thyroglossal and branchial cysts respectively. Conclusions: Clinical diagnosis is not enough in occasions, for what is necessary to appeal to means complementary diagnoses, as the Fine Needle Aspiration Biopsy; however this test is not 100% sure.

  13. Correlación clínico-citohistológica de los quistes congénitos cervicales Clinical-cytohistological correlation of cervicofacial congenital cysts

    Directory of Open Access Journals (Sweden)

    L.D. Medina Vega

    2004-02-01

    Full Text Available Objetivo: Determinar la efectividad de los diagnósticos clínico y citológico en los quistes congénitos cervicofaciales. Método: Se realizó un estudio retrospectivo de los pacientes con diagnóstico clínico, citológico y/o histológico de quiste tirogloso, branquial y dermoide, atendidos en el Hospital Universitario «Arnaldo Milián Castro», durante cinco años. Se calculó la sensibilidad, especificidad y seguridad del diagnóstico clínico y la biopsia por aspiración con aguja fina (FNAC para cada quiste. Resultado: La seguridad del diagnóstico clínico fue de 94,1%, 92,2% y 98% para los quistes tirogloso branquial y dermoide respectivamente. Encontramos mayor tendencia al error clínico en los quistes branquiales, donde las confusiones más frecuentes se presentan con linfoadenopatías inflamatorias. La seguridad de la biopsia por aspiración con aguja fina fue de 96,1% y 94,1% para los quistes tirogloso y branquial respectivamente. Conclusiones: El diagnóstico clínico no es suficiente en ocasiones, por lo que es preciso recurrir a medios diagnósticos complementarios, como la biopsia por aspiración con aguja fina; sin embargo esta prueba no es 100% segura.Objective: To determine the effectiveness of clinical and cytological diagnosis in congenital cysts located in head and neck. Method: We were carried out a retrospective study of patients with clinical, cytological or histological diagnosis of thyroglossal, branchial and dermoid cyst, assisted in the University Hospital Arnaldo Milián Castro", during five years. It was calculated the sensibility, specificity and security of the clinical diagnosis and the Fine Needle Aspiration Biopsy for each cyst. Result: The security of the clinical diagnosis it was respectively of 94,1%, 92,2% and 98% for the thyroglossal, branchial and dermoid cysts. We find bigger tendency to the clinical error in branchial cysts, where the most frequent confusions are presented with inflammatory linfoadenopathy. The security of the Fine Needle Aspiration Biopsy was of 96,1% and 94,1% for the thyroglossal and branchial cysts respectively. Conclusions: Clinical diagnosis is not enough in occasions, for what is necessary to appeal to means complementary diagnoses, as the Fine Needle Aspiration Biopsy; however this test is not 100% sure.

  14. Giant Ovarian Cyst: a Case Report Quiste gigante de ovario: presentación de un caso

    Directory of Open Access Journals (Sweden)

    Mario Joel Arroyo Díaz

    2011-11-01

    Full Text Available The giant cysts ovarian growths are rare in the gynecological conditions. We present the case of a patient of 62 years of age, of white color of the skin, weight 73 kg. He came to the General Teaching Hospital "Enrique Cabrera" referring volume increase progressive on the abdomen for a year and a half of evolution without another symptom companion in its beginning, but in recent months caused her lack of air before the efforts, urinated with more frequent than usual and with a lack of appetite. He was diagnosed with cystic mass dependent on ovary, by ultrasonography and computed axial tomography. The practical laparotomy and was resected ovarian cyst left from 21 kg in weight. The anatomopathological study further reported a mucinous cystadenoma ovarian tumor Brenner associated.Los quistes gigantes de ovario son tumoraciones poco frecuentes en las afecciones ginecológicas. Se presenta el caso de una paciente de 62 años de edad, de color de piel blanca, peso 73 kg. que acudió al Hospital General Docente “Enrique Cabrera” refiriendo aumento progresivo de volumen del abdomen, de un año y medio de evolución sin otro síntoma acompañante en su comienzo, pero en los últimos meses le provocaba falta de aire ante los esfuerzos, orinaba con más frecuencia de lo acostumbrado y con falta de apetito. Se le diagnosticó una masa quística dependiente de ovario, por ultrasonografía y Tomografía Axial Computarizada. Se practicó laparotomía y se resecó quiste de ovario izquierdo de 21 kg. de peso. El estudio anatomopatológico ulterior reportó un cistoadenoma mucinoso de ovario con tumor de Brenner asociado.

  15. Testicular cancer knowledge among deaf and hearing men.

    Science.gov (United States)

    Sacks, Loren; Nakaji, Melanie; Harry, Kadie M; Oen, Marcia; Malcarne, Vanessa L; Sadler, Georgia Robins

    2013-09-01

    Testicular cancer typically affects young and middle-aged men. An educational video about prostate and testicular cancer was created in American Sign Language, with English open captioning and voice overlay, so that it could be viewed by audiences of diverse ages and hearing characteristics. This study recruited young Deaf (n = 85) and hearing (n = 90) adult males to help evaluate the educational value of the testicular cancer portion of this video. Participants completed surveys about their general, testicular, and total cancer knowledge before and after viewing the video. Although hearing men had higher pre-test scores than Deaf men, both Deaf and hearing men demonstrated significant increases in General, Testicular, and Total Cancer Knowledge scores after viewing the intervention video. Overall, results demonstrate the value of the video to Deaf and hearing men. PMID:23813488

  16. Combination of radiotherapy and cetuximab for patients suffering from of an advanced and non operable epidermoid carcinoma of the ORL sphere: results and side effects

    International Nuclear Information System (INIS)

    The authors report a retrospective survey of a set of locally advanced epidermoid carcinomas treated by irradiation and cetuximab. They assessed the response to the treatment, the specific survival, and the global survival as well as the tolerance. The survey is based on 31 men and 5 women suffering from different stage 4 non-metastatic advanced epidermoid carcinomas of the ORL sphere. Short communication

  17. TESTICULAR CANCER – THE SUCCESS OF MULTIMODAL THERAPY

    Directory of Open Access Journals (Sweden)

    L. Miron

    2006-01-01

    Full Text Available Testicular neoplasia constitutes a chapter of particular interest in oncology, given its increased curability in comparison with most solid tumors. Early diagnosis is important because it allows the patients to be treated in the first stages of the disease, in which morbidity associated with therapy is minimal, and increased survival represents certitude. The medical staff, as well as the general population, must be advised upon suggestive signs and symptoms, and also on the imaging characteristics of such cancers (ultrasound and CAT scans being in the spotlight, so that the period of time until confirmation of the diagnosis (by pathology exam – which in turn influences therapy decision – is obtained may be as short as possible. Surgery represents a very important component of multimodal therapeutic strategy for patients diagnosed with testicular cancer, both for low/volume tumors and for the more advanced stages of disease. Surgical interventions (orchiectomy, retroperitoneal lymph node resection with or without sympathic nerve preservation, resection of singular metastases contribute decisively to the high percentage of long term cures, and can play a role in increasing the survival of patients with chemoresistant metastatic disease. Chemotherapy is mandatory in the treatment of locally advanced and metastasis seminomatous germ cell tumors (GCT. This may be seen also as an option to annihilate possible pathology diagnostic errors (mostly due to lack of tumour marker dosing which determine a non-seminomatous GCT to be treated as a seminoma, thus greatly diminishing therapeutic efficacy. There are several chemotherapeutic agents with extremely efficient activity on seminomatous testicular tumours, but the etoposide/cisplatin protocol remains still the gold standard. Non-seminomatous GCTs have a lesser response to chemotherapy and therefore a higher relapse rate and a poorer prognosis.

  18. Radiotherapy Treatment Planning for Testicular Seminoma

    Energy Technology Data Exchange (ETDEWEB)

    Wilder, Richard B., E-mail: richardbwilder@yahoo.com [Department of Radiation Oncology, Moffitt Cancer Center, Tampa, FL (United States); Buyyounouski, Mark K. [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Efstathiou, Jason A. [Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA (United States); Beard, Clair J. [Department of Radiation Oncology, Dana-Farber/Brigham and Women' s Cancer Center, Boston, MA (United States)

    2012-07-15

    Virtually all patients with Stage I testicular seminoma are cured regardless of postorchiectomy management. For patients treated with adjuvant radiotherapy, late toxicity is a major concern. However, toxicity may be limited by radiotherapy techniques that minimize radiation exposure of healthy normal tissues. This article is an evidence-based review that provides radiotherapy treatment planning recommendations for testicular seminoma. The minority of Stage I patients who choose adjuvant treatment over surveillance may be considered for (1) para-aortic irradiation to 20 Gy in 10 fractions, or (2) carboplatin chemotherapy consisting of area under the curve, AUC = 7 Multiplication-Sign 1-2 cycles. Two-dimensional radiotherapy based on bony anatomy is a simple and effective treatment for Stage IIA or IIB testicular seminoma. Centers with expertise in vascular and nodal anatomy may consider use of anteroposterior-posteroanterior fields based on three-dimensional conformal radiotherapy instead. For modified dog-leg fields delivering 20 Gy in 10 fractions, clinical studies support placement of the inferior border at the top of the acetabulum. Clinical and nodal mapping studies support placement of the superior border of all radiotherapy fields at the top of the T12 vertebral body. For Stage IIA and IIB patients, an anteroposterior-posteroanterior boost is then delivered to the adenopathy with a 2-cm margin to the block edge. The boost dose consists of 10 Gy in 5 fractions for Stage IIA and 16 Gy in 8 fractions for Stage IIB. Alternatively, bleomycin, etoposide, and cisplatin chemotherapy for 3 cycles or etoposide and cisplatin chemotherapy for 4 cycles may be delivered to Stage IIA or IIB patients (e.g., if they have a horseshoe kidney, inflammatory bowel disease, or a history of radiotherapy).

  19. Synchronous thyroid and colon metastases from epidermoid carcinoma of the lung: case report / Metástases sincrônicas de carcinoma epidermoide de pulmão em tireoide e cólon: relato de caso

    Scientific Electronic Library Online (English)

    Carla Rameri Alexandre Silva de, Azevedo; Loureno, Cezana; Eduardo Sampaio Patrício de, Moraes; Maria Dirley Ferreira de Souza, Begnami; Tadeu Ferreira, Paiva Júnior; Aldo Lourenço Abbade, Dettino; Marcello Ferretti, Fanelli.

    2010-12-01

    Full Text Available CONTEXTO: O câncer de pulmão de células não pequenas evolui, na maioria dos casos, com metástases a distância. Ossos, sistema nervoso central, glândula adrenal e fígado são os sítios mais frequentes de metástases. Disseminação para pele, miocárdio, tireoide e intestino pode ocorrer, entretanto é rar [...] a. RELATO DE CASO: Descrevemos um caso de carcinoma espinocelular (CEC) de pulmão com metástase em cólon e tireoide, em mulher de 66 anos. A lesão era irressecável, e foi iniciada quimioterapia. A paciente evoluiu com suboclusão intestinal e a colonoscopia evidenciou pólipo colônico cuja biópsia e imunoistoquímica (IHQ) foram compatíveis com CEC de origem pulmonar. Em consulta de acompanhamento, detectou-se nódulo tireoidiano cuja punção aspirativa e IHQ de cellblock confirmaram CEC de origem pulmonar. Após quimioterapia de terceira linha, a paciente evoluiu com abdome agudo obstrutivo por massa retroperitoneal, sendo submetida a laparotomia exploradora, vindo a falecer por complicações da cirurgia. Metástases para tireoide e cólon são raramente reportadas em carcinomas epidermoides de pulmão. O envolvimento gastrointestinal por metástases de pulmão pode acometer estômago, intestino delgado e cólon, e casos de sangramento e perfuração já foram reportados. Embora ricamente vascularizada, a tireoide é sítio infrequente de metástases. Os sítios refletem prognósticos reservados na evolução clínica. Não encontramos, na literatura, relato prévio de câncer de pulmão com metástases em cólon e tireoide concomitantes em um único paciente. Abstract in english CONTEXT: Non-small cell lung cancer (NSCLC) progresses to distant metastases in most cases. The most frequent sites for distant metastases are the bones, central nervous system, adrenal glands and liver. Dissemination to the skin, myocardium, thyroid gland and intestine may occur, but is rare. CASE [...] REPORT: We describe a case of squamous cell carcinoma in the lungs, with metastases in the colon and thyroid, in a 66-year-old female patient. The lesion was unresectable and chemotherapy was started. The patient evolved with intestinal subocclusion, and colonoscopy showed the presence of a polyp. Biopsy and immunohistochemical analysis on the polyp showed that it was compatible with squamous cell carcinoma of pulmonary origin. At a follow-up consultation, the patient presented a thyroid nodule. A aspiration biopsy and cellblock immunohistochemistry confirmed the squamous cell carcinoma of pulmonary origin. After third-line chemotherapy, the patient progressed with acute obstructive abdomen due to a retroperitoneal mass. She underwent exploratory laparotomy and died due to surgical complications. Metastases to the thyroid and colon are rarely reported in cases of epidermoid carcinoma of the lungs. Gastrointestinal involvement in pulmonary metastases may affect the stomach, small intestine and colon, and cases of bleeding and perforation have already been reported. Although richly vascularized, the thyroid is an infrequent site for metastases. Such sites reflect poor prognoses for the clinical evolution. We did not find any previous reports in the literature, on lung cancer with metastases concomitantly in the colon and thyroid, in a single patient.

  20. Esplenomegalia gigante por quiste esplénico: Presentación de un caso / Giant splenomegaly due to splenic tumor: A case presentation

    Scientific Electronic Library Online (English)

    Janet, Domínguez Cordovés; Julio, Díaz Mesa; Glenis, Madrigal Batista; Simeón, Collera Rodríguez; Ramiro, Torres Core; Rocío, Queral Gómez Quintero; Gaspar, Alcalde Mustelier.

    2006-06-01

    Full Text Available Los quistes del bazo como causa de esplenomegalia son extremadamente raros pero no excepcionales. Dentro de ellos los secundarios o seudoquistes son los más frecuentes y más informados en la literatura. Sus formas de presentación son muy variables y oscilan entre dolor abdominal intenso y presentaci [...] ón asintomática. El tratamiento también es muy controversial y varía desde técnicas mínimamente invasivas hasta la esplenectomía total. En nuestro centro ingresó una paciente con el diagnóstico de tumor retroperitoneal, que una vez estudiado resultó ser un quiste esplénico. El objetivo de este trabajo es exponer todos los elementos concernientes a esta paciente, a fin de dar a conocer los estudios, hallazgos quirúrgicos y resultados anatomopatológicos

  1. Interest of the serous dosage of HER-2/neu, EGFr, VEGF, IL6 and Ac anti-P53 among patients damaged by an esophagus epidermoid carcinoma, type epidermoid carcinoma whom treatment was an exclusive chemoradiotherapy

    International Nuclear Information System (INIS)

    The serous concentrations of EGFr and HER2/neu seem to have a potential interest in the framework of the assumption of esophagus epidermoid carcinomas. A next step consists in comparing the serous value of these markers with their tissue expression on biopsies. A prospective study in parallel of a therapeutic trial is starting up to validate these results on a bigger number of patients. (N.C.)

  2. Clinical importance and prevalence of testicular microlithiasis in pediatric patients / Importância clínica e prevalência de microlititíase testicular em pacientes pediátricos

    Scientific Electronic Library Online (English)

    Robson Azevedo, Dutra; Adriana Cartafina, Perez-Bóscollo; Edilaine Cristian, Melo; João Celso, Cruvinel.

    2011-10-01

    Full Text Available OBJETIVO: Avaliar a prevalência de microlitíase testicular entre pacientes pediátricos com afecções inguinoescrotais. MÉTODOS: Estudo prospectivo entre janeiro de 2005 a janeiro de 2010, utilizando ultrasonografia escrotal em 1504 crianças (de 1 a 15 anos) com afecções inguinoescrotais. RESULTADOS: [...] Microlitíase testicular foi identificada em 20 testículos de 11 crianças (0,71% dos 1504 pacientes). 5 crianças com criptorquidia (3,93% de 127 pacientes), 4 com testículo retrátil (14,8% de 27 pacientes), 1 com hipotrofia testicular e 1 com hérnia inguinal (0,07% de 1349 crianças). As crianças foram avaliadas anualmente com exame físico e ultrassonografia inguinoescrotal. CONCLUSÕES: A microlitíase testicular é uma entidade rara, ocorrendo em 0,7% dos pacientes pediátricos com afecções inguinoescrotais. A associação com a criptorquidia, testículo retrátil e a hipotrofia testicular foi significativa. Abstract in english PURPOSE: To evaluate the prevalence of testicular microlithiasis among pediatric patients with inguinoscrotal affections. METHODS: Between January 2005 and January 2010, we evaluated, prospectively 1504 children ranging from 1 to 15 years with inguinoscrotal affections with a high-frequency ultrasou [...] nd system, which employs a 10-MHz transducer. RESULTS: Testicular microlithiasis was identified in 20 testes of eleven children (0.71% of 1504 patients evaluated), through an ultrasound scan. Testicular microlithiasis was found in 5 children with cryptorchidism (3.93% of 127 patients), 4 children with retractile testes (14.8% of 27 patients), 1 child with a hypotrophic testis (100% of 1 patient), and 1 child with inguinal hernia (0.07% of 1349 patients). The children with testicular microlithiasis were submitted to annual physical examinations and ultrasound evaluations. CONCLUSIONS: Testicular microlithiasis was a rare condition and occurred in 0.7% of the subjects studied. The association with cryptorchidism, retractile and hypotrophic testis was significant.

  3. Quistes del rafe medio del pene. Presentación de dos casos / Penile medial raphe cysts. Presentation of two cases

    Scientific Electronic Library Online (English)

    Niurka, García Sosa; Francisco J, Fong Aldama.

    2014-08-01

    Full Text Available Los quistes del rafe medio del pene son lesiones benignas, infrecuentes en urología pediátrica, y usualmente asintomáticos. Se localizan en la región parameatal y borde inferior del prepucio. Se presentaron dos casos que acudieron a consulta de Urología, por el hallazgo del quiste por parte de los p [...] adres de los pacientes. Ambos quisten tenían de 1 a 2 cm de diámetro. Ninguno de los casos reportados se les había realizado la circuncisión previamente. A los dos casos se les hizo la marsupialización del quiste mediante cirugía ambulatoria, siendo la evolución post operatoria satisfactoria. Abstract in english Penile medial raphe cysts are benign lesions, infrequent in pediatric urology, usually asymptomatic. They are located in the parameatal region and the low edge of the foreskin. We presented two cases assisting to the Urology consultation because the patients´ parents discovered the cysts. Both cysts [...] were 1- 2cm diameter. No one of the patients was previously circumcised. It was carried out the marsupialization of both cysts in ambulatory surgery, being satisfactory post-surgery evolution.

  4. Quiste broncogénico de la pared torácica: Caso clínico y revisión de la literatura Bronchogenic cyst in the chest wall

    Directory of Open Access Journals (Sweden)

    David Schnettler R.

    2003-09-01

    Full Text Available Los quistes broncogénicos se ubican en la mayoría de los casos en la cavidad torácica, en relación con el árbol bronquial, en la periferia del parénquima pulmonar o en el mediastino. Sin embargo, existen casos infrecuentes en que el quiste se localiza en la pared torácica, principalmente en el tejido celular subcutáneo presternal, en la región cervical y el abdomen. Se postula que la ubicación fuera de la cavidad torácica ocurre por migración, o pinzamiento del tejido pulmonar normal durante la fusión de los procesos esternales o diafragmáticos. En este artículo, se presenta como caso clínico, un paciente 10 años de edad, de sexo masculino, que presentó una lesión nodular presternal, confirmada como quiste broncogénico en el estudio histológico. Se revisa la literatura al respecto y se discute el enfoque diagnóstico y terapéutico más adecuado a esta patologíaThe majority of bronchogenic cysts are found in the thoracic cavity, principally the bronchial tree, the peripheral lung parenchyma or the mediastinum. However, infrequently the cysts are found in the thoracic wall, mainly in the presternal subcutaneous tissues, the cervical region or the abdomen. It is postulated that cysts found outside the thoracic cavity occur by migration or by entrapment of normal pulmonary tissue during the embryonic fusion of the sternum or diaphragm. We present a case of a 10 year old boy who presented with a nodular presternal lesion, histologically confirmed as a brochogenic cyst. We review the literature and discuss the diagnosis and most adequate treatment

  5. Infección experimental en el perro con quistes de Entamoeba coli asociados al estreptococo hemolítico por vía oral

    Scientific Electronic Library Online (English)

    Víctor M., Ayulo Robles.

    1944-03-01

    Full Text Available El 94.1 % de los animales a los que les dimos en su alimentación quistes de Entamoeba coli, mezclados con cultivos de Estreptococo hemolítico y que recibieron un enema de retención, de la mezcla de cultivos en caldo de Estreptococo hemolítico más, bilis de buey, reprodujeron el cuadro agudo de la di [...] sentería amebiana, siendo las lesiones anátomo-patológicas e histológicas, semejantes a las obtenidas por otros autores, empleando para sus experiencias E. histolytica. El 100 % de los controles a los que se incluyó en su alimentación, solo cultivos de Estreptococo hemolítico y que recibieron un enema de retención de la mezcla de cultivo de Estreptococo y bilis de buey, hicieron un síndrome disenteriforme con un cuadro anátomo-patológico e histológico semejante a los que se les dió la mezcla de quistes de E. coli más Estreptococo hemolítico. En tanto que el 100 % de los que solamente recibieron en su dieta alimenticia quistes de E. coli, no presentaron en ningún momento, formas vegetativas de E. coli (en las heces) y, a la autopsia, no revelaron lesión anátomopatológica alguna.

  6. Non-seminomatous testicular germ cell tumours

    International Nuclear Information System (INIS)

    This report deals with the preliminary results of trials in the DATECA project with stage I, II and III patients with non-seminomatous germ cell tumours. Stage 1 patients were randomized between infradiaphragmatic irradiation and observation. No significant difference in recurrence rates has been observed as yet. Eighteen of 95 patients had recurrence with a median time to relapse of 3 months. Fifteen patients achieved complete remission after treatment by combiantion chemotherapy while 3 patients are still undergoing treatment. Stage II patients received 6 series of cis-platinum, bleomycin, and vinblastine. The patients were initially randomized to receive chemotherapy alone versus chemotherapy plus irradiation. Irradiation led to increased toxicity and decreased doses of the antineoplastic drugs. Fifty-one patients were studied. The overall complete remission rate was 89 per cent including 7 patients who achieved complete remission after secondary surgery. Three patients died from testicular tumours and two toxic deaths occurred in this group. Stage III patients were treated with 6 series of cis-platinum, bleomycin, and vinblastine. Fifty patients were studied. The complete remission rate was 72 per cent including 2 patients who achieved complete remission after secondary surgery. Sixteen patients relapsed after achieving complete remission with a median time to relapse of 4 months. Eight of these died, 4 achieved a new complete remission, while 4 patients are still under treatment. Sixty per cent of the patients are at present alive without evidence of disease, while 12 patients died from testicular tumours and 2 from toxic side effects. (orig.)

  7. Incidence of testicular microlithiasis in patients with ?-thalassemia major.

    Science.gov (United States)

    Rahimi, Rahil; Foroughi, Amin Abolhasani; Haghpanah, Sezaneh; Bahmanyar, Maryam; Jelodari, Shohreh; De Sanctis, Vincenzo; Karimi, Mehran

    2015-11-01

    We assessed the prevalence of testicular microlithiasis by scrotal ultrasonography in ?-thalassemia major patients older than 10 years and evaluated the association with serum ferritin levels, calcium (Ca), phosphate (Ph), and parathyroid hormone levels (PTH). In this cross-sectional study, 132 male ?-thalassemia major patients from 300 male patients older than 10 years old were randomly evaluated by scrotal ultrasonography. Parathyroid hormone, calcium, phosphate, and serum ferritin levels were also evaluated. All of the patients were urologically asymptomatic. One hundred healthy age-matched subjects were selected as control group. Testicular microlithiasis was found in 16 patients and 1 individual in control group (12.1 vs 1 %; p?=?0.003). Testicular microlithiasis was associated with age and high serum ferritin levels, but there was no association between Ca, Ph, and PTH levels; blood transfusion; and oral or subcutaneous iron chelation therapy. Also, there was no significant correlation between hyperparathyroidism, history of viral hepatitis, and splenectomy with testicular microlithiasis. The frequency of testicular microlithiasis in ?-thalassemia major patients was higher than previously reported. A correlation was found between testicular microlithiasis with age and serum ferritin levels, so regular and adequate iron chelator therapy (at least 10-12 h per day for 5-6 days a week) is recommended. We suggest a close observation and treatment with iron-chelating agents of these patients. Since testicular microlithiasis is occasionally associated with germ cell tumors, clinical and sonographic follow-up is recommended. PMID:26251156

  8. Evaluation of Doppler Indices in Varicocele-Related Testicular Atrophy

    Directory of Open Access Journals (Sweden)

    Masoud Nemati

    2010-05-01

    Full Text Available Background/Objective: Varicocele is a well-recognized cause of decreased testicular function and atrophy and occurs in approximately 15-20% of all men and 40% of infertile men. The aim of this study was to evaluate varicocele-related testicular atrophy with Duplex sonography. "nPatients and Methods: Fifty patients (mean age 24±7.43 with testicular atrophy due to varicocele were included in the study during 2005-2008."nResults: Echogenicity of the atrophic testis was homogeneous. The mean peak systolic velocity (PSV and resistive index (RI in intratesticular arteries for atrophic and normal testes were 5.45 ± 2.22 cm/s, 0.63±0.12 and 6.38 ±2.12 cm/s, 0.61± 0.17, respectively. The differences were not significant (P > 0.05. "nConclusion: Varicocele-related testicular atrophy is not associated with testicular parenchymal heterogeneity and it does not affect the intratesticular and testicular arterial PSV or RI."nKeywords: Varicocele, Testicular Atrophy, Peak Systolic Velocity, Resistive Index

  9. Efficacy of Liposomal Monensin on the Enhancement of the Antitumour Activity of Liposomal Ricin in Human Epidermoid Carcinoma (KB) Cells

    OpenAIRE

    Tyagi, N; S. S. Rathore; Ghosh, P C

    2013-01-01

    The monensin, known to enhance the cytotoxicity of ricin and ricin-based immunotoxins is a very hydrophobic molecule and this limits its administration in optimum doses under in vivo conditions. In order to realise its full potential, monensin was intercalated into various liposomal formulations and its ability to potentiate the cytotoxicity of ricin liposomes in human epidermoid carcinoma (KB) cells was studied. It was observed that ricin cytotoxicity enhancing ability of monensin liposome d...

  10. Valor pronóstico del parámetro inmunohistoquímico p53 en los estadios I y II del carcinoma epidermoide de lengua móvil

    Scientific Electronic Library Online (English)

    J., Sánchez Jiménez; D., Gómez Ángel; H., Galera Ruiz.

    2003-10-01

    Full Text Available Objetivo: El propósito de este estudio fue evaluar el marcador inmunohistoquímico p53 como factor pronóstico en pacientes que presentaban carcinoma epidermoide de lengua móvil en estadios I y II. Material y método: Se realizó un estudio retrospectivo de 36 pacientes (grupo homogéneo), correspondient [...] es a un periodo de estudio de 10 años, comprendido entre los años 1985 y 1994. Las muestras procedieron de piezas quirúrgicas incluidas en bloques de parafina. Los estudios inmunohistoquímicos se han realizado aplicando la técnica inmunoperoxidásica, método ABC (complejo streptavidina-biotina-peroxidasa). Resultados y conclusiones: En la muestra homogénea estudiada, se apreció una relación significativa directa entre la inmunotinción positiva para p53 y la probabilidad de aparición de recidiva y/o muerte por enfermedad, así como una relación inversa entre la inmunotinción positiva para p53 y el tiempo medio de supervivencia en pacientes que presentaban carcinoma epidermoide de lengua móvil. Abstract in english Objetive: The purpose of this study was evaluating immunohistochemical marker p53 as a prognosis (diagnosis) factor in patients which presented mobile tongue epidermoid carcinoma in stages I and II. Material and method: A retrospective study was carried out to 36 patients (homogeneous group) corresp [...] onding to a study period of 10 years from 1985 to 1995. Samples came from surgical pieces included in paraffin blocks. Immunohistochemical studies were made by using immunoperoxidase technique method ABC (streptavidin-biotin- peroxidase complex). Results and conclusion: In the homogeneous sample case studied it a direct significant relation between positive immunotinción for p53 and the probability of reccurrence and/or death because of disease, as well as inverse relation between positive immunotinción for p53 and survival average time in patients which presented mobile tongue epidermoid carcinoma was observed.

  11. Value of bone scanning in patients with testicular tumors

    International Nuclear Information System (INIS)

    In order to evaluate the potential of routine bone scanning in the follow-up investigation of patients with testicular tumors, 238 scans from 124 patients were retrospectively analysed. 155/238 (65%) of all bone scans were normal. Benign lesions of arthrotic and traumatic origin were seen in 75 (32%) patients. Only 6 sceletal scans were suspicious but X-ray findings excluded metastatic lesions. From 1979 to 1986 no bone metastases from testicular tumors were seen in any patient. Thus, sceletal scintigraphy is not suitable for routine performance in follow-up examinations of patients with testicular tumors. (orig.)

  12. Familial testicular tumour in two brothers: A case report

    Directory of Open Access Journals (Sweden)

    Gupta M

    2005-01-01

    Full Text Available Testicular tumors account for 1% of all cancers in men and it occurs in 1 in 500 men. Incidence of familial testicular tumours is rare. Total number of cases till the year 1992 in identical twins is 21, in brothers 82 and father-son both affected in 31 pairs. We report a case of two brothers presenting simultaneously with testicular tumours. Both were subjected to retrograde orchidectomy. Histopathologic examination of one revealed embryonal cell carcinoma and other mature teratoma of the testis. Patient with embryonal carcinoma was given adjuvant chemotherapy based on Bleomycin, Etoposide and cisplatinum (BEP and one with mature teratoma was put on a follow up.

  13. Metástasis testicular metacrónica secundaria a adenocarcinoma renal de células claras / Metachronic testicular metastasis secondary to clear cell renal adenocarcinoma

    Scientific Electronic Library Online (English)

    Roberto, Llarena Ibarguren; Jorge, García-Olaverri Rodríguez; Igor, Azurmendi Arin; Ivan, Olano Grasa; Carlos, Pertusa Peña.

    2008-05-01

    Full Text Available Objetivo: Presentar un caso de metástasis inusual en testículo de origen renal. Método: Paciente de 57 años afecto y en tratamiento por un cáncer renal derecho diseminado que durante su evolución con terapia médica aparecieron metástasis óseas y un nódulo doloroso en polo superior testicular derecho [...] , que obligó a cirugía, con resultado de metástasis de adenocarcinoma de células claras. Resultado: A los 6 meses el paciente sigue en tratamiento con sorafenib oral sin que se hayan manifestado más implantes metastáticos. Conclusiones: Los tumores secundarios metástasicos en testes suponen menos del 1% del total de tumores testiculares. En pacientes en la 5ª y 6ª década, sobre todo afectos de otras neoplasias, las masas testiculares acostumbran a ser implantes metastáticos. El origen más frecuente es el prostático. Abstract in english Objective: To report one case of unusual testicular metastasis from a renal origin. Methods: 57-year-old patient with disseminated right renal cancer under treatment who presented bone metastasis and a painful nodule in the upper pole of the right testicle during his follow-up with medical therapy, [...] making surgery necessary. The pathology result was clear cell adenocarcinoma. Results: Six months later the patient continues under oral Sorafenib without evidence of new metastatic implants. Conclusions: Testicular secondary metastatic tumors account for less than 1% of old testicular tumors. In patients in the fifth and sixth decades, mainly if they are affected by other neoplasias, testicular masses use to be metastatic implants. The most frequent origin is prostate.

  14. Tratamiento laparoscópico del quiste hidatídico hepático Laparoscopic treatment of liver hydatid cysts

    Directory of Open Access Journals (Sweden)

    PEDRO PINTO G

    2011-08-01

    Full Text Available El objetivo es mostrar los detalles técnicos, protocolo de manejo, costos y resultados del tratamiento laparoscópico de quiste hidatídico hepático (QHH. Se presenta un análisis prospectivo y descriptivo de una serie de 31 casos consecutivos de pacientes portadores de QHH operados entre enero de 2006 y enero de 2009, en el Hospital Regional de Coyhaique. Se incluye a todos los pacientes portadores de QHH tipo I, III, los tipo II y IV sintomáticos, menores a 5 cms según la clasificación de la OmS. Previo a la realización de la cirugía se les indicó 15 días de Albendazol y 2 meses en el post-operatorio. La técnica quirúrgica empleada consistió en la evacuación de la membrana parasitaria, resección parcial de la periquística prominente y sutura de las comunicaciones biliares. Siempre se utilizó drenaje. Los 31 pacientes presentaron 40 quistes, 17 de las cuales fueron mujeres, con un promedio de edad de 37 años. El estudio radiológico reveló que el 68,6 de ellos correspondió a quistes univesiculares, siendo únicos en el 74%, localizados principalmente en el lóbulo hepático derecho (68%. Ei tiempo quirúrgico alcanzó a ios 79,83 minutos. Hubo dos conversiones (6,45%, la morbilidad alcanzó al 24%. La estadía promedio fue de 6 días. El período de seguimiento fue de 28 meses, con una recidiva de 3,5%. No hubo mortalidad en esta serie. El costo del tratamiento laparoscópico del QHH promedió los US 2.107. Creemos que la técnica laparoscópica, aplicada con criterio selectivo, es una alternativa útil para el tratamiento de pacientes con hidatidosis hepática, pues sus resultados son comparables a los existentes con cirugía abierta.Background: Laparoscopic surgery is emerging as a useful alternative for the treatment of liver hydatid cysts. Aim: To report technical data, management protocols, costs and results of laparoscopic management of liver hydatid cysts. Material and Methods: Prospective analysis of 31 patients aged 5 to 73 years (17 females, with 40 cysts, operated between 2006 and 2009. All patients received albendazol for 15 days prior to surgery and for 2 months afterwards. Surgical technique consisted in the evacuation of parasite membrane, partial excision of prominent pericystic membrane and suture of biliary communications. Results: Sixty nine percent of cysts were uni-vesicular, 74% were unique and 68% were located in the right lobe. Surgical time was 80 min. Two patients were converted to open surgery and 24% had postoperative complications. Mean hospital stay was six days. Patients were followed for 28 months and in 4% the cyst relapsed. No patient died. The mean cost of laparoscopic treatment was US$ 2.107. Conclusions: Laparoscopic technique is a useful surgical alternative for the treatment of liver hydatid cysts.

  15. Tratamiento laparoscópico del quiste hidatídico hepático / Laparoscopic treatment of liver hydatid cysts

    Scientific Electronic Library Online (English)

    PEDRO, PINTO G; CLAUDIO, VALLEJOS O; EDUARDO, CRUCES; JOSÉ, LOBOS G; FRANCISCO, HERNÁNDEZ G; MARCELO, RÍOS M; JOSÉ, GÁLVEZ M.

    2011-08-01

    Full Text Available El objetivo es mostrar los detalles técnicos, protocolo de manejo, costos y resultados del tratamiento laparoscópico de quiste hidatídico hepático (QHH). Se presenta un análisis prospectivo y descriptivo de una serie de 31 casos consecutivos de pacientes portadores de QHH operados entre enero de 200 [...] 6 y enero de 2009, en el Hospital Regional de Coyhaique. Se incluye a todos los pacientes portadores de QHH tipo I, III, los tipo II y IV sintomáticos, menores a 5 cms según la clasificación de la OmS. Previo a la realización de la cirugía se les indicó 15 días de Albendazol y 2 meses en el post-operatorio. La técnica quirúrgica empleada consistió en la evacuación de la membrana parasitaria, resección parcial de la periquística prominente y sutura de las comunicaciones biliares. Siempre se utilizó drenaje. Los 31 pacientes presentaron 40 quistes, 17 de las cuales fueron mujeres, con un promedio de edad de 37 años. El estudio radiológico reveló que el 68,6 de ellos correspondió a quistes univesiculares, siendo únicos en el 74%, localizados principalmente en el lóbulo hepático derecho (68%). Ei tiempo quirúrgico alcanzó a ios 79,83 minutos. Hubo dos conversiones (6,45%), la morbilidad alcanzó al 24%. La estadía promedio fue de 6 días. El período de seguimiento fue de 28 meses, con una recidiva de 3,5%. No hubo mortalidad en esta serie. El costo del tratamiento laparoscópico del QHH promedió los US 2.107. Creemos que la técnica laparoscópica, aplicada con criterio selectivo, es una alternativa útil para el tratamiento de pacientes con hidatidosis hepática, pues sus resultados son comparables a los existentes con cirugía abierta. Abstract in english Background: Laparoscopic surgery is emerging as a useful alternative for the treatment of liver hydatid cysts. Aim: To report technical data, management protocols, costs and results of laparoscopic management of liver hydatid cysts. Material and Methods: Prospective analysis of 31 patients aged 5 to [...] 73 years (17 females), with 40 cysts, operated between 2006 and 2009. All patients received albendazol for 15 days prior to surgery and for 2 months afterwards. Surgical technique consisted in the evacuation of parasite membrane, partial excision of prominent pericystic membrane and suture of biliary communications. Results: Sixty nine percent of cysts were uni-vesicular, 74% were unique and 68% were located in the right lobe. Surgical time was 80 min. Two patients were converted to open surgery and 24% had postoperative complications. Mean hospital stay was six days. Patients were followed for 28 months and in 4% the cyst relapsed. No patient died. The mean cost of laparoscopic treatment was US$ 2.107. Conclusions: Laparoscopic technique is a useful surgical alternative for the treatment of liver hydatid cysts.

  16. HISTOLOGIA TESTICULAR HUMANA COMPARADA, ADULTO JOVEN Y SENIL HUMAN TESTICULAR HISTOLOGY IN YOUNG AND SENILE MEN

    OpenAIRE

    Héctor Rodríguez; Paulina Salazar; Nadia Schmidt; Patricia Torres; Enrique Ossandón

    1999-01-01

    In general, sperm production decreases with advanced age in men. Therefore the present work compares the histology and cellularity of aging human testis with that of a young adult. Gonads from three patients 69 years old and testis from a young subject (aged 25 years) were examined after histological standard techniques (PAS-Haematoxyline). Histological, morphometric and cell counting analyses of testicular sections revealed that the seminiferous tubules of senile patients were of smaller dia...

  17. VARIACIONES DEL FUNCIONAMIENTO TESTICULAR Octopus mimus ADULTOS TESTICULAR FUNCTION VARIATIONS IN ADULT Octopus mimus

    OpenAIRE

    Alberto Olivares Paz; Eduardo Bustos-Obregón; Vivian Castillo Alvarez; Oscar Zúñiga Romero

    2003-01-01

    Octopus mimus macho madura precozmente. En general, sobre 200 g son maduros y permanecen en dicha condición hasta la muerte. En consideración a que no hay antecedentes de la fisiología testicular de los machos adultos, fueron estudiadas la función gamética mediante análisis histológico de los túbulos seminíferos y la función endocrina, cuantificando en el testículo, progesterona y testosterona, en conjunto con el crecimiento y funcionalidad de los órganos blancos del andrógeno. Se detectaron ...

  18. Quiste tirogloso con granuloma de colesterol en una escolar simulando carcinoma de tiroides

    Scientific Electronic Library Online (English)

    Maryori, García; Enrique, Marquina; Carmen, Fuenmayor; María Fernanda, Marquina; Eduardo, Marquina; Carlos, Marquina; Anna, García; Astrid, Cantor.

    2013-10-01

    Full Text Available Objetivo: Presentar el caso de una escolar con quiste tirogloso y granuloma de colesterol, hallazgo inusual que simuló clínica e imagenológicamente un carcinoma de tiroides. Esta asociación es infrecuente y hay pocos casos reportados. Caso clínico: Escolar femenina de 11 años, quién consultó por pre [...] sentar disfagia y tumoración en región anterolateral izquierda del cuello, de 3x3 cm, de consistencia dura, dolorosa a la palpación, sin signos de flogosis. Ultrasonido de cuello evidenció conducto tirogloso permeable en la línea media con presencia de nódulo hipoecoico, de bordes bien definidos, sin calcificaciones que medía 1,8 x 0,9 cm. Se extirpó la tumoración que medía 3x2, 5x0, 8cm. y se observó cavidad quística de 0,8 cm. de diámetro mayor que contenía material de aspecto gelatinoso. Por debajo de éste, se observó nódulo bien circunscrito de 1,5 cm. de diámetro mayor, constituido por tejido firme de color blanco-amarillento. El estudio histopatológico reveló un quiste revestido por epitelio cilíndrico y respuesta inflamatoria linfohistiocitaria, con células gigantes tipo “cuerpo extraño” alrededor de hendiduras; que correspondían a d dd epósito de colesterol. Conclusión: Se presenta este caso por su rareza y porque puede confundirse clínica e imagenológicamente con una neoplasia maligna. Asimismo, pudiera corresponder al primer caso reportado en nuestro país. Abstract in english Objective: We report the case of a 11 year- old girl with thyroglossal cyst and cholesterol granuloma, an unusual finding that clinically simulates thyroid carcinoma. This association is unusual and there are few reported cases worldwide. Case report: An 11-year-old girl consulted for dysphagia and [...] a 3 x 3 cm hard mass. The mass was painful on palpation and was located in the anterolateral neck left. It was phlogosis-free. A neck ultrasound showed a 1.8 x 0.9 cm permeable midline thyroglossal conduct with a hypoechoic nodule with well-defined edges but without calcifications. A 3 x 2,5 x 0, 8cm tumor was removed. A 0.8 cm cystic cavity that contained gelatinous material was observed. Below that cavity, a well-circumscribed nodule was observed. It measured 1.5 cm and was made up of firm yellowish tissue. The histopathology examination revealed a cyst lined with columnar epithelium and inflammatory linfohistiocitic response with foreign body type giant cells around cracks that corresponded to a cholesterol deposit. Conclusion: We present this case because it is very unusual and because it can be clinically and radiologically mistaken for a malignant tumor. It could be the first case ever reported in Venezuela.

  19. Transverse testicular ectopia, a case report and review of literature

    Directory of Open Access Journals (Sweden)

    Moslemi, Mohammad Kazem

    2011-01-01

    Full Text Available Crossed testicular ectopia (CTE/transverse testicular ectopia (TTE is a rare but well known congenital anomaly, in which both gonads migrate toward the same hemiscrotum. It is usually associated with other abnormalities such as persistent Mullerian duct syndrome, true hermaphroditism, inguinal hernia, hypospadias, pseudohermaphroditism, and scrotal anomalies. About 100 cases of transverse testicular ectopia have been reported in published studies. We report a case of transverse testicular ectopia in an 8-month-old boy who presented with right inguinal hernia and nonpalpable left testis. On exploration, both testes were present in the right inguinal region. Bilateral orchiopexy was performed by crossing the left testis in the extra-peritoneal space and ipsilateral scrotal orchiopexy. The diagnosis could not be made preoperatively in most of reported cases.

  20. Testicular germ cell tumor fungating through anterior abdominal wall

    OpenAIRE

    Ghosh, Indranil; Raina, V.

    2011-01-01

    Retroperitoneal lymph node metastases from testicular germ cell tumor are common, but fungation of such mass through the anterior abdominal wall is extremely rare. We report such a case which had a favorable response to chemotherapy.

  1. Metachronous bilateral testicular germ cell tumors: Report of two cases

    Directory of Open Access Journals (Sweden)

    James Francis

    2009-01-01

    Full Text Available Metachronous bilateral testicular germ cell tumors is a rare known problem. However, no report of metachronus bilateralism was identified in the PubMed database published from India so far, where testicular cancer is relatively rare. We report the cases of two gentlemen. One had stage 1 nonseminomatous germ cell tumor (NSGCT at the age of 32 in 1990 and developed marker relapse on surveillance and had chemotherapy using cisplatin and etoposide for four cycles. He developed contralateral seminoma in the testis 13 years later. Another patient had left orchidectomy in 2003 for NSGCT, had adjuvant BEP for two cycles, and developed a contralateral testicular tumor 5 years later, which was also seminoma. As more patients with germ cell tumors are cured with chemotherapy, long-term problems become important. Contralateral testicular tumor is one of them. As it can be very late, many years of continued follow-up examination and patients? awareness are necessary.

  2. Male Infertility Might Signal Higher Odds of Testicular Cancer

    Science.gov (United States)

    ... nih.gov/medlineplus/news/fullstory_155748.html Male Infertility Might Signal Higher Odds of Testicular Cancer Abnormally ... men who underwent semen analysis as part of infertility treatment between 1996 and 2011. They were compared ...

  3. [Testicular and paratesticular tumors in children].

    Science.gov (United States)

    Fabbro, M A; Costa, L; Cimaglia, M L; Donadio, P; Spata, E

    1995-01-01

    Testis tumors in children occur infrequently and exibit differences in their histopathology, clinical behaviour and therapy from their adult counterparts. From 1979 to 1994, 17 children and adolescent with testicular tumors were treated at the Pediatric Surgical Department of Vicenza Regional Hospital. Paratesticular rabdomiosarcoma were present in 3 cases, 4 patients had embrional carcinoma, 1 Sertoli cell tumor, 2 Leydig cell gonadal stromal tumor, and leukemic infiltrates of the testis were clinically evident in 7 patients. We report our clinical series and discuss in relation to clinical characteristic, histopathology and therapy and conclude that the improved survival during the past decade is attributable to better diagnostic imaging thecniques, the availability of serum tumor markers to monitor disease activity and more effective chemotherapy. PMID:8668584

  4. ABSCESSO TESTICULAR EM HAMSTER: RELATO DE CASO

    Directory of Open Access Journals (Sweden)

    R. M. Santos

    2012-12-01

    Full Text Available The Hamster, rodent originating from the Middle East, is a species studied along with other laboratory animals as experimental models in scientific papers and currently is also created as a pet, by virtue of being docile, easy to handle and require little space for survival. The suppurative processes in domestic animals are relatively frequent. Due to infectious diseases or purulent course of aggressiveness of the environment in which they live. The habit of storing food in the cheeks with sharp edges can injure the skin and often cause abscesses in this species. However, other lesions may lead to suppuration, diseases such as testicular tumor or no tumor or not produced by damage in the skin, leading to tumescence (VITAL et al., 2007. This article reports a case of a hamster treated at the Veterinary Hospital of FAFRAM with clinical history of discomfort, anorexia and frequent licking of the scrotum. On clinical examination it was found by aspiration of purulent secretions and the presence of large numbers of polymorphonuclear cells on cytology, diagnosed with testicular abscess. The animal was taken to the operating room where was performed conventional bilateral orchiectomy and total excision of the abscess by opening the tunica vaginalis and ligation of the spermatic cord. Postoperative care included antibiotic therapy with enrofloxacin and use of an anti-inflammatory meloxicam. After ten days the stitches were removed, the wound was healing satisfactorily and the animal was in good health.O Hamster, roedor originário do Oriente Médio, é uma espécie estudada juntamente com outros animais de laboratório como modelo experimental em trabalhos científicos e, atualmente, também é criado como animal de companhia, em virtude de ser dócil, de fácil manuseio e necessitar de pequeno espaço para sobrevivência. Os processos supurativos nos animais domésticos são relativamente frequentes. Em decorrência de doenças infectocontagiosas de curso purulento ou da agressividade do meio em que vivem. No hamster, o hábito de armazenar alimentos com extremidades pontiagudas nas bochechas, pode lesionar a pele e comumente causar abscessos nesta espécie. No entanto, outras lesões podem levar à supuração, tais como afecções testiculares tumorais ou não tumorais produzidas ou não por lesão de continuidade da pele, levando à intumescência (VITAL et al., 2007. Este trabalho relata um caso de um hamster atendido no Hospital Veterinário da FAFRAM com histórico clínico de inquietação, anorexia e lambedura frequente da região escrotal. Ao exame clínico constatou-se através de punção aspirativa secreção de aspecto purulento e presença de grande quantidade de polimorfonucleares à citologia, sendo diagnosticado abscesso testicular. O animal foi encaminhado para o centro cirúrgico onde foi realizado orquiectomia bilateral convencional e exérese total do abscesso, através de abertura da túcnica vaginal e ligadura do funículo espermático. O pós-operatório incluiu antibioticoterapia com enrofloxacina e utilização de um antiinflamatório meloxican. Após dez dias os pontos foram removidos, a cicatrização da ferida cirúrgica ocorreu de maneira satisfatória e o animal apresentava-se em bom estado de saúde.

  5. Ontogenesis of testicular function in humans.

    Directory of Open Access Journals (Sweden)

    Ga??lle Angenard

    2010-01-01

    Full Text Available The two major functions of the testis, steroidogenesis and gametogenesis, take place during fetal life. These two functions have been extensively studied in rodents and adult humans. However, their onset during fetal life is poorly documented in humans. In the first part of this work we presented both our experimental data and some data of literature concerning the development of the human fetal testis. In the second part of this article, using the organ culture system we previously developed, we have investigated the regulations or perturbations of fetal testis development both in rodent and human models. Our findings provide important insight into the potential role of exposure to environmental pollutants (physical factors, in particular ionizing radiation, cadmium and endocrine disruptors such as phthalates during fetal testicular development and their potential deleterious effects on male fertility in adulthood. Our results highlight the specificity of the human model compared with rodent models.

  6. Combination of radiotherapy and cetuximab for patients suffering from of an advanced and non operable epidermoid carcinoma of the ORL sphere: results and side effects; Association de radiotherapie et de cetuximab chez des patients atteints d'un carcinome epidermoide de la sphere ORL evolue non operable: resultats et effets secondaires

    Energy Technology Data Exchange (ETDEWEB)

    Acevedo, C.; Valette, G.; Bouchekoua, M.; Marianowski, R.; Pradier, O. [CHU Morvan, 29 - Brest (France)

    2010-10-15

    The authors report a retrospective survey of a set of locally advanced epidermoid carcinomas treated by irradiation and cetuximab. They assessed the response to the treatment, the specific survival, and the global survival as well as the tolerance. The survey is based on 31 men and 5 women suffering from different stage 4 non-metastatic advanced epidermoid carcinomas of the ORL sphere. Short communication

  7. A Rare Cause of Testicular Metastasis: Upper Tract Urothelial Carcinoma

    OpenAIRE

    Manav, Alper Nesip; Kazan, Ercan; Ertek, Mehmet ?irin; Amasyal?, Ak?n Soner; Çulhac?, Nil; Erol, Haluk

    2014-01-01

    Metastatic testicular cancers are rare. Primary tumor sources are prostate, lung, and gastrointestinal tract for metastatic testicular cancers. Metastasis of urothelial carcinoma (UC) to the testis is extremely rare. Two-thirds of upper tract urothelial carcinoma (UTUC) is of invasive stage at diagnosis and metastatic sites are the pelvic lymph nodes, liver, lung, and bone. We report a rare case of metastatic UTUC to the testis which has not been reported before, except one case in the litera...

  8. Adverse testicular effects of Botox® in mature rats

    International Nuclear Information System (INIS)

    Botox® injections are taking a consistently increasing place in urology. Intracremasteric injections, particularly, have been applied for cryptorchidism and painful testicular spasms. Studies outlining their safety for this use are, however, scanty. Thus, the present study aimed at evaluating possible testicular toxicity of Botox® injections and their effect on male fertility. Mature rats were given intracremasteric Botox® injections (10, 20 and 40 U/kg) three times in a two-week interval. Changes in body and testes weights were examined and gonadosomatic index compared to control group. Semen quality, sperm parameters, fructose, protein, cholesterol and triglycerides contents were assessed. Effects on normal testicular function were investigated by measuring testosterone levels and changes in enzyme activities (lactate dehydrogenase-X and acid phosphatase). To draw a complete picture, changes in oxidative and inflammatory states were examined, in addition to the extent of connective tissue deposition between seminiferous tubules. In an attempt to have more accurate information about possible spermatotoxic effects of Botox®, flowcytometric analysis and histopathological examination were carried out. Botox®-injected rats showed altered testicular physiology and function. Seminiferous tubules were separated by dense fibers, especially with the highest dose. Flowcytometric analysis showed a decrease in mature sperms and histopathology confirmed the findings. The oxidative state was, however, comparable to control group. This study is the first to show that intracremasteric injections of Botox® induce adverse testicular effects evidenced by inhibited spermatogenesis and initiation of histopathological changes. In conclusion, decreased fertility may be a serious problem Botox® injections could cause. - Highlights: • Botox® injections are the trend nowadays, for both medical and non-medical uses. • They were recently suggested for cryptorchidism and testicular spasms. • This study outlines possible testicular adverse effects of these injections. • Botox® affected normal testicular function and physiology. • Infertility is a serious problem that Botox® injections could cause

  9. Women smoking and testicular cancer: one epidemic causing another?

    OpenAIRE

    Richiardi, Lorenzo

    2004-01-01

    In many countries the incidence of testicular cancer has increased epidemically, but the aetiology remains obscure. Maternal smoking during pregnancy has been suggested to be a cause, but a satisfactorily valid assessment of the hypothesis is still lacking. To evaluate the epidemiological relevance, we assessed the ecological correlation between female smoking habits and testicular cancer incidence in the Nordic countries. Data on smoking prevalence among women in 5-year birth cohorts 1910-19...

  10. Polychlorinated biphenyls and risk of testicular germ cell tumors

    OpenAIRE

    McGlynn, Katherine A.; Sabah M. Quraishi; Graubard, Barry I.; Weber, Jean-Philippe; Rubertone, Mark V.; Erickson, Ralph L.

    2009-01-01

    Exposure to endocrine disrupting chemicals, such as polychlorinated biphenyls (PCBs), may alter hormonal balance and thereby, increase risk of testicular germ cell tumors (TGCT). To study the relationship of PCBs to TGCT, pre-diagnostic serum samples from 736 cases and 913 controls in the Servicemen’s Testicular Tumor Environmental and Endocrine Determinants study were analyzed. Adjusted odds ratios (OR) and 95% confidence intervals (95%CI) were estimated using logistic regression. PCB levels...

  11. Compromised Rat Testicular Antioxidant Defence System by Hypothyroidism before Puberty

    OpenAIRE

    Sahoo, Dipak K.; Anita Roy

    2012-01-01

    Altered thyroid function during early stages of development is known to affect adversely testicular growth, physiology, and antioxidant defence status at adulthood. The objective of the present study is to investigate the modulation of antioxidant defence status in neonatal persistent hypothyroid rats before their sexual maturation and also to identify the specific testicular cell populations vulnerable to degeneration during neonatal hypothyroidism in immature rats. Hypothyroidism was induce...

  12. Effects of radiation therapy and chemotherapy on testicular function

    International Nuclear Information System (INIS)

    Chemotherapy and radiation therapy are commonly used alone or in combination in the curative management of many malignancies in adolescent and adult males. Over the last 15-20 years, the striking success in the treatment of some common cancers in reproductive males has led to increasing concern for damage to normal tissues, such as the testes, resulting from curative cancer treatment. Indeed, a major future goal for cancer treatment will be to improve on the complication-free cure rate. Inherent in achieving this goal is to understand the pathophysiology and clinical expression of testicular injury. Both chemotherapy and radiation therapy result in germ cell depletion with the development of oligo- to azoospermia and testicular atrophy. The type of drug (particularly the alkylating agents), duration of treatment, intensity of treatment, and drug combination are major variables in determining the extent and duration of testicular injury. Testicular injury with chemotherapy also appears to vary with the age of the patient at the time of treatment. Newer drug combinations are now being used which appear to have curative potential in tumors such as Hodgkin's disease and germ cell testicular cancer with less potential for testicular injury. The most accurate and complete information on radiation injury to the testes is derived from two studies of normal volunteers who received graded single doses directly to the testes. A clear dose-response relationship of clinical and histological testicular damage was found with gradual recovery occurring following doses of up to 600 cGy. While these two studies provide an important clinical data base, radiation therapy used in treating cancers involves multiple daily treatments, usually 25-35 delivered over several weeks. Additionally, direct testicular irradiation is seldom used clinically. 37 references

  13. Testicular function following the treatment of Hodgkin's disease in childhood.

    OpenAIRE

    Shafford, E. A.; Kingston, J. E.; Malpas, J. S.; Plowman, P N; Pritchard, J.; Savage, M.O.; Eden, O.B.

    1993-01-01

    Testicular function was studied in 40 males treated in childhood for Hodgkin's disease at St Bartholomew's Hospital, and the Hospital for Sick Children, London, between 1971-1985. All patients were 16 years or over at evaluation, and off treatment more than 6 years. Basal FSH, LH and testosterone levels were measured. Testicular size was measured using a Prader orchidometer, and all patients were offered a seminal analysis. Twenty-eight patients were treated with chemotherapy, usually ChlVPP....

  14. Phthalate-induced testicular dysgenesis syndrome: Leydig cell influence

    OpenAIRE

    Hu, Guo-Xin; Lian, Qing-Quan; Ge, Ren-Shan; Hardy, Dianne O.; Li, Xiao-Kun

    2009-01-01

    Phthalates, the most abundantly produced plasticizers, leach out from polyvinyl chloride plastics and disrupt androgen action. Male rats that are exposed to phthalates in utero develop symptoms characteristic of the human condition referred to as testicular dysgenesis syndrome (TDS). Environmental influences have been suspected to contribute to the increasing incidence of TDS in humans (i.e. cryptorchidism and hypospadias in newborn boys and testicular cancer and reduced sperm quality in adul...

  15. Improved gene expression signature of testicular carcinoma in situ

    DEFF Research Database (Denmark)

    Almstrup, Kristian; Leffers, Henrik; Lothe, Ragnhild A; Skakkebaek, Niels E; Sonne, Si B; Nielsen, John E; Rajpert-De Meyts, Ewa; Skotheim, Rolf I

    2007-01-01

    The carcinoma in situ (CIS) stage is the common precursor of testicular germ cell tumours (TGCTs) that arise in young adults. Within the past decade genome wide gene expression tools have been developed and have greatly advanced the insight into the biology of TGCTs. Two independent data sets on global gene expression in testicular CIS have been previously published. We have merged the two data sets on CIS samples (n = 6) and identified the shared gene expression signature in relation to express...

  16. Detecção do Rearranjo da Proteína BCL2/JH em Carcinomas Epidermoides de Boca e Faringe

    Directory of Open Access Journals (Sweden)

    Montovani, Jair

    2010-09-01

    Full Text Available Introdução: A proteína BCL2 encontrada na membrana mitocondrial interna, regula a apoptose inibindo a morte celular programada. A translocação (14;18, detectada em 70 a 85% dos linfomas foliculares, leva a superexpressão da proteína BCL2, pela justaposição do gene BCL2 ao segmento JH do gene da cadeia pesada da imunoglobulina. Porém, os achados da expressão da BCL2 em carcinoma de cabeça e pescoço são contraditórios. Objetivo: Investigar a presença da translocação (14;18 do gene BCL2 em carcinomas de cabeça e pescoço. Método: Foram examinadas 16 amostras de DNA, sendo 13 de carcinomas de células escamosas (CCE e 3 de epidermoide (CE, por meio da reação em cadeia da polimerase (PCR. Resultados: O rearranjo BCL2/JH foi encontrado em 2 (15% dos 13 casos de CCE e em nenhum dos 3 casos de CE. A média de frequência de moléculas com rearranjo foi de 46,44 x 107. Não foi observada associação entre a presença de rearranjo e a exposição ao tabaco e álcool (p=0,6545. Conclusão: Diferente dos resultados encontrados em linfomas foliculares a presença da translocação (14;18 em carcinomas de cabeça e pescoço não é comum e, quando ocorre, pode ser uma mutação ocasional não associada a exposição ao tabaco e álcool.

  17. Quiste óseo aneurismático mandibular de tipo sólido / Mandibular solid aneurysmal bone cyst

    Scientific Electronic Library Online (English)

    Marta, Saldaña Rodríguez; Maria Fe, García Reija; Belén, García-Montesinos Perea; Marta, Mayorga Fernández; Ramón Carlos, Saiz Bustillo.

    2013-06-01

    Full Text Available El quiste óseo aneurismático sólido es una lesión ósea benigna muy infrecuente de la que no existe consenso en relación a su origen etiopatogénico. Presenta características clínicas, radiológicas e histológicas inespecíficas, por lo que los estudios ultraestructurales son fundamentales para su diagn [...] óstico y clasificación. El diagnóstico diferencial es extenso e incluye múltiples lesiones óseas como el granuloma reparativo de células gigantes e incluso tumores malignos como el osteosarcoma. El tratamiento de elección es la cirugía conservadora. La recidiva se debe fundamentalmente a la extirpación incompleta. Abstract in english Solid aneurysmal bone cyst is a rare benign bone lesion for which no consensus exists regarding its origin. It has nonspecific clinical, radiological and histological features so ultrastructural studies are essential for diagnosis and classification. The differential diagnosis is extensive and inclu [...] des a variety of bone lesions, such as giant cell reparative granuloma, and even malignant tumors like osteosarcoma. The treatment of choice is conservative surgery. Recurrence is due mainly to incomplete resection.

  18. Hidatidosis retroperitoneal secundaria a quiste hidatídico de localización hepática / Retroperitoneal hydatidosis secondary to hepatic hydatid cyst

    Scientific Electronic Library Online (English)

    Katherina A, Vizcaychipi; Sonia, Sosa; Federico, Camicia; Graciela, Santillán; María, Casalins; María del Carmen, Nigro.

    2012-12-01

    Full Text Available La hidatidosis es una enfermedad de distribución mundial, producida por un platelminto parásito del género Echinococcus. El caso que se presenta corresponde a una paciente con una tumoración fluctuante en el espacio retroperitoneal lumbar, secundaria a un quiste hepático. El diagnóstico inicial de c [...] erteza fue dado por el hallazgo de ganchos rostelares de protoescólices en el líquido aspirado de un absceso. Este trabajo describe el cuadro clínico, el diagnóstico y el tratamiento médico-quirúrgico de esta paciente. Se analiza cómo la elaboración de un diagnóstico certero requiere de un análisis adecuado de los antecedentes epidemiológicos, las manifestaciones clínicas, los estudios de imágenes y las pruebas de laboratorio, ya que el conjunto de estos datos confirman el caso. Abstract in english Hydatid disease in a worldwide zoonosis. It is caused by a parasitic platyhelminth of the genus Echinococcus. We present a patient with a fluctuating lumbar tumor in the retroperitoneal space, secondary to a hepatic cyst. The initial diagnosis was made by identification of rostellar hooks from proto [...] scoleces in the fluid aspirated from the abscess. We herein describe the clinical manifestations, diagnosis and medical and surgical treatment of this unusual case and conclude that the development of an accurate diagnosis required a proper analysis of the patient's epidemiological history, clinical manifestations, imaging studies and laboratory tests. A multidisciplinary approach and differential diagnosis is paramount to be able to establish a cause of the disease to deliver appropriate treatment.

  19. Hidatidosis retroperitoneal secundaria a quiste hidatídico de localización hepática Retroperitoneal hydatidosis secondary to hepatic hydatid cyst

    Directory of Open Access Journals (Sweden)

    Katherina A Vizcaychipi

    2012-12-01

    Full Text Available La hidatidosis es una enfermedad de distribución mundial, producida por un platelminto parásito del género Echinococcus. El caso que se presenta corresponde a una paciente con una tumoración fluctuante en el espacio retroperitoneal lumbar, secundaria a un quiste hepático. El diagnóstico inicial de certeza fue dado por el hallazgo de ganchos rostelares de protoescólices en el líquido aspirado de un absceso. Este trabajo describe el cuadro clínico, el diagnóstico y el tratamiento médico-quirúrgico de esta paciente. Se analiza cómo la elaboración de un diagnóstico certero requiere de un análisis adecuado de los antecedentes epidemiológicos, las manifestaciones clínicas, los estudios de imágenes y las pruebas de laboratorio, ya que el conjunto de estos datos confirman el caso.Hydatid disease in a worldwide zoonosis. It is caused by a parasitic platyhelminth of the genus Echinococcus. We present a patient with a fluctuating lumbar tumor in the retroperitoneal space, secondary to a hepatic cyst. The initial diagnosis was made by identification of rostellar hooks from protoscoleces in the fluid aspirated from the abscess. We herein describe the clinical manifestations, diagnosis and medical and surgical treatment of this unusual case and conclude that the development of an accurate diagnosis required a proper analysis of the patient's epidemiological history, clinical manifestations, imaging studies and laboratory tests. A multidisciplinary approach and differential diagnosis is paramount to be able to establish a cause of the disease to deliver appropriate treatment.

  20. Quiste pilonidal gigante en un anciano Giant pilonidal cyst in an elderly man

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    Héctor Bell Santos

    2011-09-01

    Full Text Available Se describe el caso clínico de un anciano con quiste pilonidal gigante, cuya información primaria al respecto se obtuvo de la labor de terreno realizada por su médico de familia y anotada en la historia clínica individual del paciente, el cual fue intervenido quirúrgicamente y con éxito en el Servicio de Coloproctología del Hospital General Docente "Dr. Juan Bruno Zayas Alfonso" de Santiago de Cuba en enero de 2010, cuando se efectuó la exéresis total del tumor sin lesionar el recto.A case report of an elderly man with a giant pilonidal cyst, whose primary data was obtained through a medical visit carried out by the physician of the doctor's office where he belongs and written down in his medical record, is described. This patient was surgically treated with success at the Coloproctology Service from "Dr Juan Bruno Zayas Alfonso" Teaching General Hospital in Santiago de Cuba on January, 2010 when total tumor exeresis was carried out without injuring the rectum.

  1. Quiste pilonidal gigante en un anciano / Giant pilonidal cyst in an elderly man

    Scientific Electronic Library Online (English)

    Héctor, Bell Santos; Marcos Antonio, Santos Danger.

    2011-09-01

    Full Text Available Se describe el caso clínico de un anciano con quiste pilonidal gigante, cuya información primaria al respecto se obtuvo de la labor de terreno realizada por su médico de familia y anotada en la historia clínica individual del paciente, el cual fue intervenido quirúrgicamente y con éxito en el Servic [...] io de Coloproctología del Hospital General Docente "Dr. Juan Bruno Zayas Alfonso" de Santiago de Cuba en enero de 2010, cuando se efectuó la exéresis total del tumor sin lesionar el recto. Abstract in english A case report of an elderly man with a giant pilonidal cyst, whose primary data was obtained through a medical visit carried out by the physician of the doctor's office where he belongs and written down in his medical record, is described. This patient was surgically treated with success at the Colo [...] proctology Service from "Dr Juan Bruno Zayas Alfonso" Teaching General Hospital in Santiago de Cuba on January, 2010 when total tumor exeresis was carried out without injuring the rectum.

  2. Cáncer primario de tiroides en un quiste tirogloso / Primary thyroid cancer in a thyroglossal duct cyst

    Scientific Electronic Library Online (English)

    Carlos Eber, González.

    2008-06-01

    Full Text Available La patología quirúrgica congénita del cuello representa un tópico importante en el ejercicio de la cirugía en la población pediátrica. No obstante, un porcentaje no despreciable de pacientes adultos puede presentar estas alteraciones y las lesiones quísticas congénitas de la línea media del cuello, [...] específicamente las relacionadas con trastornos del desarrollo embriológico de la glándula tiroides, representan una de las patologías más frecuentes. Se presenta un caso de cáncer papilar de tiroides originado en un quiste del conducto tirogloso, en una mujer de edad adulta, una complicación por demás infrecuente, con muy pocos casos reportados en la literatura médica. Se discute su diagnóstico y manejo, basados en la revisión del tema. Abstract in english Surgical pathology of the neck constitutes an important field in pediatric surgery. Nevertheless, a significant number of adult patients may present neck pathology, and cervical midline cystic congenital lesions, specifically those related with abnormal embryologic development of the thyroid gland, [...] represent the most frequent type of abnormality. We report a case of papillary carcinoma originating in a thyroglossal duct cyst in an adult woman; very few cases have been reported in the lityerature. We discuss diagnosis and management, and include a literature review.

  3. Cáncer primario de tiroides en un quiste tirogloso Primary thyroid cancer in a thyroglossal duct cyst

    Directory of Open Access Journals (Sweden)

    Carlos Eber González

    2008-06-01

    Full Text Available La patología quirúrgica congénita del cuello representa un tópico importante en el ejercicio de la cirugía en la población pediátrica. No obstante, un porcentaje no despreciable de pacientes adultos puede presentar estas alteraciones y las lesiones quísticas congénitas de la línea media del cuello, específicamente las relacionadas con trastornos del desarrollo embriológico de la glándula tiroides, representan una de las patologías más frecuentes. Se presenta un caso de cáncer papilar de tiroides originado en un quiste del conducto tirogloso, en una mujer de edad adulta, una complicación por demás infrecuente, con muy pocos casos reportados en la literatura médica. Se discute su diagnóstico y manejo, basados en la revisión del tema.Surgical pathology of the neck constitutes an important field in pediatric surgery. Nevertheless, a significant number of adult patients may present neck pathology, and cervical midline cystic congenital lesions, specifically those related with abnormal embryologic development of the thyroid gland, represent the most frequent type of abnormality. We report a case of papillary carcinoma originating in a thyroglossal duct cyst in an adult woman; very few cases have been reported in the lityerature. We discuss diagnosis and management, and include a literature review.

  4. Quiste cervical como manifestación inicial de un microcarcinoma papilar de tiroides

    Scientific Electronic Library Online (English)

    Jorge, Fallas González; Rodolfo, Guzmán Cervantes; Carlos, Valverde Monge; Maritza, Valdés Gutiérrez.

    2012-03-01

    Full Text Available Las masas quísticas en cuello son usualmente benignas en pacientes jóvenes. Sin embargo, tumores malignos de la cabeza y el cuello pueden presentarse ocasionalmente con metástasis quísticas. Se presenta el caso de una paciente de 33 años asintomática con una masa cervical quística de gran tamaño con [...] 1 año de evolución, que inicialmente fue manejada como un quiste branquial, en quien luego de estudios por imagen e histopatológicos se sospechó carcinoma papilar de tiroides. Este diagnóstico fue corroborado en el trans-operatorio y se trató con tiroidectomía total, disección ganglionar del compartimiento central y disección ganglionar radical modificada derecha. El diagnóstico definitivo en el espécimen quirúrgico fue de un microcarcinoma papilar de tiroides con metástasis ganglionares quísticas y posteriormente la paciente recibió terapia con yodo radioactivo Abstract in english Cystic cervical masses are usually benign in the young adult population. However malignant tumors of the head and neck may present ocasionally as cystic metastasis. Herein we report a case of a 33 year old female patient, asymptomatic, with a huge cystic cervical mass of 1 year data. The initial dia [...] gnosis was a branchial clef cyst, but after imaging studies and histopathologic examination papillary thyroid carcinoma was suspected. This diagnosis was confirmed in an intraoperatory consultation, so a total thyroidectomy, central lymph node dissection and modified radical neck dissection was performed. The final diagnosis on the surgical specimen was a papillary microcarcinoma of the thyroid with cystic lymph node metastasis and the patient received radioactive iodine afterwards

  5. Quiste tímico cervical en un niño / Cervical thymic cyst in a child

    Scientific Electronic Library Online (English)

    Lissette, Nápoles Oconor; Jaime, Gonzálvez Bertot; Erich Roberto, Ramón Nuñez; Manuel, Carrazana Araujo; Orlando, Reyes Jay.

    2014-12-01

    Full Text Available Se presenta el caso clínico de un paciente de 7 años de edad con antecedentes de buena salud, quien fue ingresado a los 5 años en el Hospital Infantil Sur de Santiago de Cuba por presentar aumento de volumen en la región lateral izquierda del cuello, doloroso, sobre todo al ingerir alimentos, y fieb [...] re de 38 °C. Luego del tratamiento indicado egresó a los 10 días, pero con seguimiento por consulta externa. Al cabo de los 2 años y medio acudió a la consulta de Cirugía con aumento de volumen en la región lateral derecha del cuello. Se realizó la exéresis del tumor y los resultados del estudio anatomopatológico confirmaron que se trataba de un quiste tímico cervical Abstract in english The case report of a 7 years patient is presented with a history of good health who was admitted when he was 5 years in the Southern Pediatric Hospital from Santiago de Cuba for presenting increase of volume mainly in the left lateral region of the painful neck, when ingesting foods, and fever 38 °C [...] . After the prescribed treatment he was discharged 10 days later, but with follow up through out-patient department. After 2 and a half years he came to the Surgery Department with an increase of volume in the right lateral region of the neck. The exeresis of the tumor was carried out and the results of the pathological study confirmed that it was a thymic cervical cyst

  6. Quiste vítreo: a propósito de un caso / Vitreous cyst: a case presentation

    Scientific Electronic Library Online (English)

    J.P., Moreno-Arrones; R., Jiménez-Parras.

    2012-01-01

    Full Text Available Caso clínico: Presentamos el caso de un paciente de 12 años que refiere miodesopsias en ojo izquierdo (OI) de 6 meses de evolución. Presenta una agudeza visual (AV) de 1/0,9, en fondo de ojo izquierdo un quiste vítreo anterior. En la resonancia magnética se observa una imagen hipointensa en T1 y en [...] la ecografía en modo B una lesión hipoecoica de 3,2x4,3mm; la biomicroscopia ultrasónica puso de manifiesto un cuerpo ciliar normal. Conclusión: Dada la buena AV del paciente se observará periódicamente. Si interfiriese con el eje visual es posible fragmentarlo con láser Nd:YAG o argón, o bien su extracción vía pars plana. Abstract in english Case report: We report a case of a 12-year-old patient who complained about visual disturbances in left eye for 6 months. His visual acuity was 1/0.9, funduscopy in left eye revealed a free-floating cyst in the anterior vitreous. Magnetic resonance showed a low intense image in T1, and B-scan ultras [...] ound confirmed a hypoechogenic cyst of 3.2x4.3mm; ultrasound biomicroscopy revealed a normal ciliary body. Conclusion: Given the good VA the patient will be monitored periodically. If the cyst interferes with visual axis, management with Nd:YAG or Argon laser photocystotomy or remove it by pars plana vitrectomy has been advocated.

  7. Lymphoepithelial Cyst in Jugal Mucosa / Quiste Linfoepitelial en la Mucosa Yugal

    Scientific Electronic Library Online (English)

    Marceli Moço, Silva; Alvimar Lima de, Castro; Ana Maria Pires, Soubhia; Marcelo Macedo, Crivelini.

    2011-04-01

    Full Text Available Un quiste linfoepitelial bucal es raro, con pocos casos reportados en la literatura. El objetivo de este artículo es describir un caso clínico, centrándose en los aspectos clínicos y diagnósticos, tratamiento y pronóstico. La lesión tuvo un año de evolución, y se había desarrollado como un nódulo fi [...] broso en la mucosa yugal de un paciente de 71 años de edad con leucoderma. Teniendo en cuenta la hiperplasia fibrosa inflamatoria, fibroma y mucocele como diagnósticos diferenciales, se llevó a cabo una biopsia por escisión. Una cavidad quística limitada por epitelio pseudoestratificado sin proyecciones en el tejido conjuntivo, con tejido linfoide en el interior fue identificado microscópicamente. No se observaron eventos adversos postoperatorios, y el seguimiento clínico al año confirmó el pronóstico favorable de este tipo de lesión. Abstract in english Mouth lymphoepithelial cyst is rare, with few cases reported in literature. The aim of this article is to describe a clinical case, focusing on clinical and diagnostic aspects, treatment and prognosis. The lesion was one year old and had developed as a fibrous nodule in the jugal mucosa of a 71-year [...] -old leucoderma patient. Considering focal inflammatory fibrous hyperplasia, fibroma and mucocele as differential diagnosis, excisional biopsy was carried out. A cystic cavity limited by pseudostratified epithelium without projections into the conjunctive tissue, with lymphoid tissue within, was microscopically identified. Without postoperative adverse events, the one-year clinical followup confirmed the favorable prognosis of this kind of lesion.

  8. Ecotoxicology and Testicular Damage (Environmental Chemical Pollution): A Review Ecotoxicología y Daño Testicular. (Contaminación Química Ambiental): Revisión

    OpenAIRE

    Eduardo Bustos-Obregón; Ricardo Hartley B

    2008-01-01

    This review briefly considers the testicular damage elicited by environmental chemical pollution. It includes a short comment on environmental toxicology as an introduction to environmental chemical pollution, highlighting the importance of this current field of study and its impact on male reproductive health. Furthermore an experimental animal model addressing the effect of organophosphorated agropesticides as a testicular toxicant is presented. Moreover two relevant chemical contaminants a...

  9. Re-irradiation in stereotactic conditions and cetuximab for local relapses of epidermoid carcinoma of head and neck; Reirradiation en conditions stereotaxiques et cetuximab pour des recidives locales de carcinome epidermoide de la tete et du cou

    Energy Technology Data Exchange (ETDEWEB)

    Vasseur, F.; Comet, B.; Faivre-Pierret, M.; Coche-Dequeant, B.; Degardin, M.; Lefebvre, J.L.; Lacornerie, T.; Lartigau, E. [Departement universitaire de radiotherapie, centre Oscar Lambret, 59 - Lille (France); Universite Lille-2, 59 (France)

    2010-10-15

    The authors report a work aimed at assessing the feasibility and toxicity of a re-irradiation treatment in stereotactic conditions using CyberKnife and cetuximab in the case of local relapses of epidermoid cancers of the ORL sphere. Thirty three patients have been submitted to this treatment between June 2007 and April 2009. Although six patients died by six months, this treatment seems to be a good alternative, and presents an acceptable short-term toxicity. Further studies are needed to compare this technique to other therapeutic techniques, and to assess the risk of long term complications. Short communication

  10. Colloidal cyst of the third ventricle. Case presentation Quiste coloide del tercer ventrículo. Presentación de un caso

    Directory of Open Access Journals (Sweden)

    Joan O Rojas Fuentes

    2009-09-01

    Full Text Available

    Colloidal cysts are congenital intracranial benign lesions of the anterior superior portion of the third ventricle. They represent between the 0,2 and 2 % of all the intracranial tumours and represent the 15 or 20 % of all the intraventricular masses. They become symptomatic during the adolescence or early adulthood and start normally with migraine or symptoms of intracranial hypertension causing obstructive hydrocephaly. We present the case of a teenager of 18 years of age with history of migraine after two years and the symptoms worsened in intensity and frequency including vomiting and bilateral paresthesia; the diagnosis was obstructive hydrocephaly with colloidal cyst of the third ventricle. An appropriate practice was adopted due to the uncertain diagnosis in order to avoid neurological damage and death. We discussed the main characteristics of the colloidal cyst, its clinical presentation and radiological characteristics and we performed.

    Los quistes coloides son lesiones intracraneales congénitas benignas, de la porción antero-superior del tercer ventrículo. Suponen del 0,2 al 2 % de todos los tumores intracraneales y representan del 15 al 20 % de todas las masas intraventriculares. Comienzan a ser sintomáticos en la adolescencia o edad adulta temprana, generalmente con manifestaciones de cefalea o síntomas de hipertensión intracraneal al provocar hidrocefalia obstructiva. Se presenta una adolescente de 18 años con historia de cefalea de 2 años de evolución, cuyos síntomas fueron empeorando en intensidad y frecuencia, acompañados de vómitos y parestesias bilaterales; se le diagnosticó hidrocefalia obstructiva con quiste coloide del tercer ventrículo. Ante la sospecha del diagnóstico se tomó una conducta adecuada, para evitar el deterioro neurológico y la muerte. Se discutieron las principales características del quiste coloide, su cuadro clínico y radiológico.

  11. Vasculite testicular: uma manifestação rara de artrite reumatoide / Testicular vasculitis: a rare manifestation of rheumatoid arthritis

    Scientific Electronic Library Online (English)

    Alexandre Wagner S. de, Souza; Daniela Pereira, Rosa; Ana Letícia Pirozzi, Buosi; Ana Cecília Diniz, Oliveira; Jamil, Natour.

    2013-08-01

    Full Text Available A vasculite testicular é uma manifestação extra-articular muito rara da artrite reumatoide (AR). Descrevemos o caso de um homem de 53 anos com diagnóstico de AR por oito anos, sem controle adequado da doença. O paciente desenvolveu vasculite reumatoide, manifestada por úlceras de membros inferiores [...] e neuropatia periférica. Apresentou ainda meningite neutrofílica aguda, tendo sido tratado com antibióticos e posterior pulsoterapia endovenosa com metilprednisolona (500 mg/dia) por três dias, seguida de ciclofosfamida (2 mg/kg/ dia) e prednisona orais. O paciente apresentou melhora do quadro, mas 15 dias após a alta hospitalar, houve reativação da meningite bacteriana. O paciente foi reinternado e tratado novamente com antibióticos. Três dias depois da segunda admissão hospitalar, o paciente apresentou dor, aumento de volume do testículo esquerdo e posteriormente gangrena. Foi realizada orquiectomia unilateral e o exame anatomopatológico revelou vasculite linfocítica. O paciente faleceu dois dias após a cirurgia devido a pneumonia aspirativa. Esse caso ilustra a vasculite testicular como uma manifestação rara e grave da vasculite reumatoide. Abstract in english Testicular vasculitis is a very rare extra-articular manifestation of rheumatoid arthritis (RA). We describe the case of a 53-year-old man diagnosed with RA for eight years, who was poorly controlled and developed rheumatoid vasculitis, which manifested as leg ulcers and peripheral polyneuropathy. T [...] he patient also had acute neutrophilic meningitis and was treated with antibiotics and intravenous pulse therapy with methylprednisolone (500 mg daily) for three days, followed by oral cyclophosphamide (2 mg/kg daily) and prednisone. Overall improvement was observed, and the patient was discharged. But 15 days later, the meningitis recurred, and the patient was readmitted and treated again with antibiotics. Three days later, he developed pain and enlargement of his left testicle with gangrene. Unilateral orchiectomy was performed, revealing lymphocytic vasculitis. The patient died two days later due to aspiration pneumonia. This case illustrates a rare and severe manifestation of rheumatoid vasculitis.

  12. VARIACIONES DEL FUNCIONAMIENTO TESTICULAR Octopus mimus ADULTOS TESTICULAR FUNCTION VARIATIONS IN ADULT Octopus mimus

    Directory of Open Access Journals (Sweden)

    Alberto Olivares Paz

    2003-01-01

    Full Text Available Octopus mimus macho madura precozmente. En general, sobre 200 g son maduros y permanecen en dicha condición hasta la muerte. En consideración a que no hay antecedentes de la fisiología testicular de los machos adultos, fueron estudiadas la función gamética mediante análisis histológico de los túbulos seminíferos y la función endocrina, cuantificando en el testículo, progesterona y testosterona, en conjunto con el crecimiento y funcionalidad de los órganos blancos del andrógeno. Se detectaron tres categorías de machos adultos: maduros jóvenes, de madurez máxima y en regresión. Los animales en regresión producen menor cantidad de ambas hormonas y muestran regresión de la función espermatogénica. La declinación de ambas funciones del testículo indica el estado de envejecimiento de Octopus mimus. Por el contrario, los que están en máxima madurez tienen la mayor capacidad espermatogénica y androgénica, en conjunto con el mejor funcionamiento de las glándulas reproductivas anexas, cualidades que podrían ser consideradas en las normativas de manejo y futuras actividades de cultivo de la especieMale Octopus mimus attains precocious maturity. In general, they are mature when their weight is 200 g or more and remain so until death. Since testicular physiology in adult males is not known, spermatogenesis was analyzed by histological observation of seminiferous tubules and endocrine function by quantification of testicular concentration of progesterone and testosterone together with growth and functionality of the androgen target organs. Three classes of adult males were identified : young mature, maximal maturity and regression. Regressed animals produce less of both hormones tested and show spermatogenic involution. These two traits denote ageing in O. mimus. On the contrary maximal maturity shows high spermatogenic and steroidogenic function and of the glands in the reproductive male tract. These characteristics should be considered for adequate commercial exploitation of this species

  13. VARIACIONES DEL FUNCIONAMIENTO TESTICULAR Octopus mimus ADULTOS / TESTICULAR FUNCTION VARIATIONS IN ADULT Octopus mimus

    Scientific Electronic Library Online (English)

    Alberto, Olivares Paz; Eduardo, Bustos-Obregón; Vivian, Castillo Alvarez; Oscar, Zúñiga Romero.

    Full Text Available Octopus mimus macho madura precozmente. En general, sobre 200 g son maduros y permanecen en dicha condición hasta la muerte. En consideración a que no hay antecedentes de la fisiología testicular de los machos adultos, fueron estudiadas la función gamética mediante análisis histológico de los túbulo [...] s seminíferos y la función endocrina, cuantificando en el testículo, progesterona y testosterona, en conjunto con el crecimiento y funcionalidad de los órganos blancos del andrógeno. Se detectaron tres categorías de machos adultos: maduros jóvenes, de madurez máxima y en regresión. Los animales en regresión producen menor cantidad de ambas hormonas y muestran regresión de la función espermatogénica. La declinación de ambas funciones del testículo indica el estado de envejecimiento de Octopus mimus. Por el contrario, los que están en máxima madurez tienen la mayor capacidad espermatogénica y androgénica, en conjunto con el mejor funcionamiento de las glándulas reproductivas anexas, cualidades que podrían ser consideradas en las normativas de manejo y futuras actividades de cultivo de la especie Abstract in english Male Octopus mimus attains precocious maturity. In general, they are mature when their weight is 200 g or more and remain so until death. Since testicular physiology in adult males is not known, spermatogenesis was analyzed by histological observation of seminiferous tubules and endocrine function b [...] y quantification of testicular concentration of progesterone and testosterone together with growth and functionality of the androgen target organs. Three classes of adult males were identified : young mature, maximal maturity and regression. Regressed animals produce less of both hormones tested and show spermatogenic involution. These two traits denote ageing in O. mimus. On the contrary maximal maturity shows high spermatogenic and steroidogenic function and of the glands in the reproductive male tract. These characteristics should be considered for adequate commercial exploitation of this species

  14. Metástasis neurológicas secundarias a tumor testicular germinal / Neurological metastases secondary to germ cell testicular tumor

    Scientific Electronic Library Online (English)

    Roberto, Llarena Ibarguren; Igor, Azurmendi Arín; Jorge, García-Olaverri Rodríguez; Ivan, Olano Grasa; Emilio, Canton Aller; Carlos, Pertusa Peña.

    2008-10-01

    Full Text Available Objetivo: Las metástasis neurológicas secundarias a tumores urológicos suponen un 12% del total. Las derivadas de los tumores germinales testiculares en la época del cisplatino son excepcionales. Métodos: Presentamos un caso de tumor germinal mixto en un varón de 49 años tratado mediante quimioterap [...] ia sistémica desde 18 meses antes que presentó severa clínica neurológica central y periférica, que le condujo a la muerte por hemorragia cerebral masiva. Resultados: Se describen 3 tipos de presentación de las metástasis cerebrales en pacientes con cáncer testicular. El tipo 1 en el que se presentan sincrónicamente al tumor primario. El tipo 2 en el que se diagnostican tras un período de remisión luego del tratamiento citostático convencional. En el tipo 3 las metástasis se diagnostican durante el curso de la enfermedad y durante su tratamiento. Conclusiones: Salvo en caso de metástasis únicas encuadradas en el grupo 1 y 2 susceptibles de cirugía o radiocirugía, en el que cabe esperar respuesta, en el resto de lesiones secundarias a tumores germinales la evolución y el pronóstico son ominosos, con supervivencias escasas. Abstract in english Objective: Neurological metastases secondary to urological tumors account for 12% overall. The ones derived from germ cells testicular tumors are exceptional in the age of cisplatin. Methods: We report one case of mixed germ cell tumor in a 49-year-old male patient treated with systemic chemotherapy [...] during 18 months before presenting with severe central and peripheral neurological symptoms leading to death due to massive cerebral hemorrhage. Results: We describe three types of presentation of cerebral metastases in patients with testicular cancer. Type 1 present synchronically with the primary tumor. Type 2 are diagnosed after a period of remission after conventional cytostatic treatment. Type 3 metastases are diagnosed during the course of the disease and its treatment. Conclusions: Except unique metastases classified in groups I and 2, which are susceptible of surgery or radiosurgery, in which in response may be expected; the rest of lesions secondary to germ cell tumors have an ominous prognosis and outcomes, with short survivals.

  15. Review of photodynamic therapy with 5-methyl aminolevulinate in actinic keratosis, epidermoid carcinoma and basal cell carcinoma

    International Nuclear Information System (INIS)

    A bibliographic review was conduced on the use of 5-methyl aminolevulinate in dermatology, specifically in the treatment of actinic keratosis, epidermoid carcinoma and basal cell carcinoma. The basic fundamentals of photodynamic therapy are described. The preparation and method of use of photodynamic therapy with 5-methyl aminolevulinate (MAL-PDT) are detailed. The clinical studies that were realized with photodynamic therapy for the treatment of actinic keratosis, epidermoid carcinoma and basal cell carcinoma are mentioned. Different photo-inducible agents and other current therapeutic options of first-line are compared. The MAL-PDT has have the advantage of to present less side effects and the same have been more tolerable than liquid nitrogen and 5 fluorouracil. The MAL-PDT has been considered as an effective option for the treatment of Bowen's disease. Invasive epidermoid carcinoma has existed without evidence to support the routine use of this therapeutic. For superficial basal cell carcinoma, the MAL-PDT has presented a high cure rate and transient and manageable side effects in extensive and multiple lesions. The MAL-PDT has been an effective and safe treatment in patients with basal cell carcinoma, for those with less depth of 2mm. The MAL-PDT could play an important role in the field of prevention with immunosuppressed patients, particularly, those that have required transplant and its immunosuppression has been pharmacological. The use or not of the MAL-PDT, should be evaluated individually for each patient and to have suitable characteristics for each disease that was cited in this review. The photodynamic therapy with 5-methyl aminolevulinate has been a therapeutic modality of considerable economy, however, it should be evaluated in the context of number of inquiries and side effects that have offered other therapeutic modalities

  16. Development of a New and Efficient Laboratory Method for Processing Testicular Sperm

    OpenAIRE

    Hammitt, Diane G.; Ferrigni, Robert G.; Sattler, Chris A.; Rebert, Jessica A.; Singh, Anita P.

    2002-01-01

    Purpose: Testicular biopsy specimens contain large amounts of debris that makes sperm pick-up for ICSI more difficult than with epididymal aspirates. We sought to develop improved processing techniques for testicular sperm extraction (TESE).

  17. Neoplasias associadas ao carcinoma epidermóide do esôfago / Esophageal epidermoid cancer associated neoplasms

    Scientific Electronic Library Online (English)

    C.C., Schirmer; R., Gurski; M.A.A., Castro; G.S.P., Madruga; F.L., Pedroso; C.D.P., Kruel; L., Brentano.

    1997-12-01

    Full Text Available INTRODUÇÃO. O carcinoma epidermóide de esôfago (CEE) tem uma importante associação com neoplasias do trato aerodigestivo e, provavelmente, compartilham dos mesmos fatores de risco. Além destes, outras neoplasias podem estar associadas com o carcinoma de esôfago. OBJETIVO. Analisar, retrospectivament [...] e, pacientes com carcinoma epidermóide do esôfago tratados pelo Grupo de Cirurgia do Esôfago, Estômago e Intestino Delgado (GCEEID) do Hospital de Clínicas de Porto Alegre (HCPA), no período de janeiro/88 a junho/95, os quais tinham neoplasias associadas ao CEE. PACIENTES E MÉTODOS. Dentre os 261 pacientes estudados, 19 (7,28%) tinham neoplasia associada ao CEE. Dez pacientes apresentaram tumores sincrônicos e 9, metacrônicos. O sexo predominante foi o masculino, com 17 casos. A média de idade ficou em 62,52 anos no momento do diagnóstico da neoplasia esofágica. RESULTADOS. Os tumores aerodigestivos, na sua totalidade carcinomas escamosos, representaram o tipo histológico predominante da neoplasia associada em 68,42% dos casos. O sítio mais freqüente da neoplasia aerodigestiva associada foi a árvore respiratória (53,8%), seguido da cavidade oral e orofaringe (23%) e laringe (23%). Dos 19 pacientes, 12 eram tabagistas e nove ingeriam bebidas alcoólicas regularmente. Para o tratamento do CEE, optou-se por cirurgia em seis pacientes. A neoplasia associada foi tratada com cirurgia radical em 11 pacientes e radioterapia em cinco. Surpreendentemente, foram diagnosticados quatro casos (21%) de adenocarcinomas gástricos associados ao CEE, tratados com cirurgia radical em três pacientes. CONCLUSÃO. Os autores ressaltam a importância do estadiamento criterioso dos pacientes com CEE devido a associação significativa com outras neoplasias, principalmente com tumores aerodigestivos. Alertam para o seguimento desses pacientes e discutem a possibilidade de fatores de risco comuns: fumo e álcool. Nesta casuística, encontrou-se associação importante com neoplasias gástricas. Abstract in english INTRODUCTION. The esophageal epidermoid cancer has an important association with aerodigestive tract neoplasms and possibly share the same risk factors. Furthermore, other neoplasms can be associated with esophagus cancer. OBJECTIVE. To analyze retrospectively the patients with esophageal epidermoid [...] cancer (EEC) and associated neoplasms, treated by the Esophagus Stomach and Small Intestine Group of Surgery at Hospital de Clinicas de Porto Alegre from January 1988 to June 1995. PATIENTS AND METHODS. Nineteen (7.28%) of the 261 studied patients had associated neoplasms to the EEC. Ten patients presented synchronic tumours and 9 metachronic ones. The predominant sex was the masculine with 17 cases. The mean age was 62.52 years in the moment of the esophageal cancer diagnostic. RESULTS. The aerodigestive tumours, squamous carcinomas in totality, represented the predominant associated neoplasm histological type in 68.42% of the cases. The most frequent associated aerodigestive tumours site was the respiratory tract (53.8%), followed by the oral cavity and oropharynx (23%) and larynx (23%). In our sample, twelve patients were smokers and 9 were alcohol abusers. In relation to the EEC treatment, surgery was performed in 6 patients. The associated neoplasm was treated with radical surgery in 11 patients and radiotherapy in 5. Surprisingly 4 cases (21%) of gastric adenocarcinoma associated to the EEC were diagnosed, treated with radical surgery in 3 patients. CONCLUSION. The authors call attention to the importance of a criterial staging as well as the follow up in patients with EEC owing to the significant association with others neoplasms, principally with aerodigestive tumours, and discuss the common risk factors possibility: tobacco and alcohol use. Important association with gastric neoplasms were found in this casuistry.

  18. Neoplasias associadas ao carcinoma epidermóide do esôfago Esophageal epidermoid cancer associated neoplasms

    Directory of Open Access Journals (Sweden)

    C.C. Schirmer

    1997-12-01

    Full Text Available INTRODUÇÃO. O carcinoma epidermóide de esôfago (CEE tem uma importante associação com neoplasias do trato aerodigestivo e, provavelmente, compartilham dos mesmos fatores de risco. Além destes, outras neoplasias podem estar associadas com o carcinoma de esôfago. OBJETIVO. Analisar, retrospectivamente, pacientes com carcinoma epidermóide do esôfago tratados pelo Grupo de Cirurgia do Esôfago, Estômago e Intestino Delgado (GCEEID do Hospital de Clínicas de Porto Alegre (HCPA, no período de janeiro/88 a junho/95, os quais tinham neoplasias associadas ao CEE. PACIENTES E MÉTODOS. Dentre os 261 pacientes estudados, 19 (7,28% tinham neoplasia associada ao CEE. Dez pacientes apresentaram tumores sincrônicos e 9, metacrônicos. O sexo predominante foi o masculino, com 17 casos. A média de idade ficou em 62,52 anos no momento do diagnóstico da neoplasia esofágica. RESULTADOS. Os tumores aerodigestivos, na sua totalidade carcinomas escamosos, representaram o tipo histológico predominante da neoplasia associada em 68,42% dos casos. O sítio mais freqüente da neoplasia aerodigestiva associada foi a árvore respiratória (53,8%, seguido da cavidade oral e orofaringe (23% e laringe (23%. Dos 19 pacientes, 12 eram tabagistas e nove ingeriam bebidas alcoólicas regularmente. Para o tratamento do CEE, optou-se por cirurgia em seis pacientes. A neoplasia associada foi tratada com cirurgia radical em 11 pacientes e radioterapia em cinco. Surpreendentemente, foram diagnosticados quatro casos (21% de adenocarcinomas gástricos associados ao CEE, tratados com cirurgia radical em três pacientes. CONCLUSÃO. Os autores ressaltam a importância do estadiamento criterioso dos pacientes com CEE devido a associação significativa com outras neoplasias, principalmente com tumores aerodigestivos. Alertam para o seguimento desses pacientes e discutem a possibilidade de fatores de risco comuns: fumo e álcool. Nesta casuística, encontrou-se associação importante com neoplasias gástricas.INTRODUCTION. The esophageal epidermoid cancer has an important association with aerodigestive tract neoplasms and possibly share the same risk factors. Furthermore, other neoplasms can be associated with esophagus cancer. OBJECTIVE. To analyze retrospectively the patients with esophageal epidermoid cancer (EEC and associated neoplasms, treated by the Esophagus Stomach and Small Intestine Group of Surgery at Hospital de Clinicas de Porto Alegre from January 1988 to June 1995. PATIENTS AND METHODS. Nineteen (7.28% of the 261 studied patients had associated neoplasms to the EEC. Ten patients presented synchronic tumours and 9 metachronic ones. The predominant sex was the masculine with 17 cases. The mean age was 62.52 years in the moment of the esophageal cancer diagnostic. RESULTS. The aerodigestive tumours, squamous carcinomas in totality, represented the predominant associated neoplasm histological type in 68.42% of the cases. The most frequent associated aerodigestive tumours site was the respiratory tract (53.8%, followed by the oral cavity and oropharynx (23% and larynx (23%. In our sample, twelve patients were smokers and 9 were alcohol abusers. In relation to the EEC treatment, surgery was performed in 6 patients. The associated neoplasm was treated with radical surgery in 11 patients and radiotherapy in 5. Surprisingly 4 cases (21% of gastric adenocarcinoma associated to the EEC were diagnosed, treated with radical surgery in 3 patients. CONCLUSION. The authors call attention to the importance of a criterial staging as well as the follow up in patients with EEC owing to the significant association with others neoplasms, principally with aerodigestive tumours, and discuss the common risk factors possibility: tobacco and alcohol use. Important association with gastric neoplasms were found in this casuistry.

  19. Epidermoid carcinoma of the anal canal. A series of 276 cases

    Energy Technology Data Exchange (ETDEWEB)

    Papillon, J.; Montbarbon, J.F.

    1987-05-01

    During the past ten years, substantial progress has been made in the knowledge of the natural history of epidermoid carcinoma of the anal canal and of the response of the disease to radiotherapy alone or combined with chemotherapy. At the present time, the main problem in the management of this tumor concerns identification of the best modalities to achieve local control and preservation of anal function. From a series of 276 cases, followed for more than three years, the necessity for a careful pretreatment evaluation was stressed. This included a systematic search for pelvic metastatic lymph nodes by palpation and CT scan. All patients were treated initially by irradiation except those who underwent groin dissection for inguinal node metastasis or colostomy for complete anal obstruction. Three groups of patients have been identified: unresectable or disseminated tumors (33 cases), resectable tumors but not suitable for sphincter conservation (21 cases) treated by radiochemotherapy and delayed surgery, and resectable tumors suitable for sphincter conservation (222 cases) which were treated by a split-course regimen combining a short course of carefully planned external beam irradiation (19 days) followed by an iridium 192 implant after a two-month rest. In this group, which represents 80 percent of the whole series, 80 percent of patients have had their cancer controlled and 90 percent of controlled patients have retained normal anal function. The use of chemotherapy during the first days of irradiation is advisable in all cases to reinforce the efficacy of treatment and increase the chance of anal preservation. Results of the split-course regimen, combining external beam and interstitial irradiation, demonstrate a clear superiority over external beam irradiation alone, especially for large infiltrating tumors, which represent the majority of cases.

  20. Epidermoid carcinoma of the anal canal. A series of 276 cases

    International Nuclear Information System (INIS)

    During the past ten years, substantial progress has been made in the knowledge of the natural history of epidermoid carcinoma of the anal canal and of the response of the disease to radiotherapy alone or combined with chemotherapy. At the present time, the main problem in the management of this tumor concerns identification of the best modalities to achieve local control and preservation of anal function. From a series of 276 cases, followed for more than three years, the necessity for a careful pretreatment evaluation was stressed. This included a systematic search for pelvic metastatic lymph nodes by palpation and CT scan. All patients were treated initially by irradiation except those who underwent groin dissection for inguinal node metastasis or colostomy for complete anal obstruction. Three groups of patients have been identified: unresectable or disseminated tumors (33 cases), resectable tumors but not suitable for sphincter conservation (21 cases) treated by radiochemotherapy and delayed surgery, and resectable tumors suitable for sphincter conservation (222 cases) which were treated by a split-course regimen combining a short course of carefully planned external beam irradiation (19 days) followed by an iridium 192 implant after a two-month rest. In this group, which represents 80 percent of the whole series, 80 percent of patients have had their cancer controlled and 90 percent of controlled patients have retained normal anal function. The use of chemotherapy during the first days of irradiation is advisable in all cases to reinforce the efficacy of treatment and increase the chance of anal preservation. Results of the split-course regimen, combining external beam and interstitial irradiation, demonstrate a clear superiority over external beam irradiation alone, especially for large infiltrating tumors, which represent the majority of cases

  1. Prevalencia de quistes odontogénicos: Hospital Regional Valdivia entre los años 1990 y 2010 / Prevalence of odontogenic cysts: Hospital Regional Valdivia, between years 1990-2010

    Scientific Electronic Library Online (English)

    F.I., Peters; G.P., López; E.G., Preisler; C.C., Sotomayor; Z.M., Donoso; V.S., Hernández.

    2012-12-01

    Full Text Available Objetivo: Determinar la prevalencia de quistes odontogénicos en población atendida en el Hospital Regional Valdivia, en el periodo entre 1990-2010, según la última clasificación de lesiones quísticas de la Organización Mundial de la Salud (OMS), 2005. Esta investigación corresponde a un estudio desc [...] riptivo de corte transversal censal. Metodología: Se revisaron informes de biopsias del Hospital Regional Valdivia (HRV), durante un periodo de 20 años (1990-2010),seleccionando los informes con diagnósticos histopatológicos de quistes odontogénicos. Las variables a analizar fueron: año de emisión del informe, género y edad del paciente, localización anatómica de la lesión, diagnóstico histopatológico. Los datos se almacenaron en planilla de base de datos para su análisis estadístico. Resultados: De las 1.850 biopsias del territorio maxilofacial evaluadas, la prevalencia de Quistes Odontogénicos alcanzó un 11,9%. Según tipo de quiste, los más prevalente fueron el quiste radicular (84,5%), quiste dentígero (14,1%) y quiste residual (0,9%). El de menor prevalencia fue el quiste de erupción (0,5%). Un 52,7% del total de quistes odontogénicos correspondieron al género femenino. El rango de edad de presentación va entre los 4 y los 81 años (promedio 31,7±3,7 años). El área anatómica más afectada es el maxilar superior con 65,5%. Conclusión: Los Quistes odontogénicos son entidades diagnosticadas histopatológicamente en forma variable durante el periodo de tiempo comprendido entre los años 1990 y 2010, en el HRV. Se presentan en mayor frecuencia en mujeres, sin predilección por género, afectando principalmente a la 3ª década de vida. La entidad quística mas prevalente fue el quiste radicular. Abstract in english Objective: Determine the prevalence of Odontological Cysts in the attended patients of Hospital Regional Valdivia, between 1990 and 2010, according to the World Health Organization (WHO) classification of tumour like lesions, 2005. This investigation corresponds to a descriptive cross-sectional stud [...] y. Method: The biopsy reports of the Hospital Regional Valdivia, during a 20 years period (1990-2010), were analyzed, selecting those with Odontological Cysts histopathological diagnosis. The analyzed variables were: year of the biopsy report; patient's gender and age; anatomical location of the lesion and histopathological diagnosis. The extracted data were stored in a data base for descriptive statistical analysis. Results: Within the 1850 biopsies found from the maxilofacial region, the Odontological Cysts prevalence was 11.9%. According to the type of cyst, the most prevalent was Radicular/Periapical Cyst (84.5%), followed by Dentigerous/Folicular Cyst (14.1%), and then Residual Cyst (0.9%). The least prevalent was Eruption Cyst (0.5%). 52.7% of all Odontological Cystswere found in women. The cysts's presentation among age ranges was between 4 and 81 years old (average 31.7±3.7 years old). The most frequently affected anatomical region was the superior maxilla (65.5%). Conclusion: Odontological Cysts are histopathologically diagnosed lesions in varying ways between 1990 and 2010 at Hospital Regional Valdivia. Without gender predilection, they present most commonly affecting women, mainly those in the 3rd decade of life. The most common cystic lesion found was Radicular/Periapical Cyst.

  2. Investigación experimental de la equinococosis canina a partir de quiste hidatídico de origen porcino en México

    Directory of Open Access Journals (Sweden)

    Zuñiga-A Ismael

    1999-01-01

    Full Text Available OBJETIVO: Para evaluar la infección y obtener el estado adulto del cestodos, se buscó reproducir la equinococosis en perros a partir de quiste hidatídico de origen porcino. MÉTODOS: Se formaron 2 grupos, uno de 5 y otro de 3 perros, a cada animal del grupo experimental se le dió 2 g de membrana germinativa de quíste hidatídico fértil por vía oral, el segundo grupo fue testigo. Ambos grupos fueron evaluados clínica, serológica y parasitológicamente, en el grupo experimental se sacrificó un animal el día 35 de la infección y los siguientes cada 5 dias hasta el 55, en el segundo grupo todos se sacrificaron el día 55. Se observaron huevos del cestodos en heces a partir del dia 51 postinfección. La evaluación morfológica se realizó mediante observación microscópica del raspado de mucosa intestinal. RESULTADOS: De 50 cestodos analizados, 10 de cada uno de los perros infectados, 49 (98% presentaron 3 proglótidos y 1 (2% tenía 4; 18 (36% de los cestodos presentaban un proglótido grávido. La longitud de los estróbilos varió de 1,6 a 2,6 mm. El número promedio de los ganchos largos y cortos fue de 31 y 34 respectivamente. La longitud de los ganchos largos varió entre 0,081 y 0,09 mm, los ganchos cortos fluctuaron entre 0,034 y 0,041 mm. En los perros evaluados clínicamente, el número de leucocitos y la cantidad de proteínas plasmáticas fue significativamente mayor en el grupo testigo (P < 0,05; la cantidad de alfa globulinas fue mayor en el grupo infectado (P < 0,05. CONCLUSIONES: Los resultados permiten confirmar el ciclo perro-cerdo y una infección subclínica en los huéspedes definitivos, lo que dificulta su diagnóstico y control en una especie intimamente relacionada con el hombre.

  3. Investigación experimental de la equinococosis canina a partir de quiste hidatídico de origen porcino en México

    Directory of Open Access Journals (Sweden)

    Ismael Zuñiga-A

    1999-06-01

    Full Text Available OBJETIVO: Para evaluar la infección y obtener el estado adulto del cestodos, se buscó reproducir la equinococosis en perros a partir de quiste hidatídico de origen porcino. MÉTODOS: Se formaron 2 grupos, uno de 5 y otro de 3 perros, a cada animal del grupo experimental se le dió 2 g de membrana germinativa de quíste hidatídico fértil por vía oral, el segundo grupo fue testigo. Ambos grupos fueron evaluados clínica, serológica y parasitológicamente, en el grupo experimental se sacrificó un animal el día 35 de la infección y los siguientes cada 5 dias hasta el 55, en el segundo grupo todos se sacrificaron el día 55. Se observaron huevos del cestodos en heces a partir del dia 51 postinfección. La evaluación morfológica se realizó mediante observación microscópica del raspado de mucosa intestinal. RESULTADOS: De 50 cestodos analizados, 10 de cada uno de los perros infectados, 49 (98% presentaron 3 proglótidos y 1 (2% tenía 4; 18 (36% de los cestodos presentaban un proglótido grávido. La longitud de los estróbilos varió de 1,6 a 2,6 mm. El número promedio de los ganchos largos y cortos fue de 31 y 34 respectivamente. La longitud de los ganchos largos varió entre 0,081 y 0,09 mm, los ganchos cortos fluctuaron entre 0,034 y 0,041 mm. En los perros evaluados clínicamente, el número de leucocitos y la cantidad de proteínas plasmáticas fue significativamente mayor en el grupo testigo (P < 0,05; la cantidad de alfa globulinas fue mayor en el grupo infectado (P < 0,05. CONCLUSIONES: Los resultados permiten confirmar el ciclo perro-cerdo y una infección subclínica en los huéspedes definitivos, lo que dificulta su diagnóstico y control en una especie intimamente relacionada con el hombre.

  4. Testicular changes observed in boars following experimental inoculation with pseudorabies (Aujeszky's) virus.

    OpenAIRE

    Hall, L. B.; Kluge, J P; Evans, L E; Clark, T L; Hill, H T

    1984-01-01

    Four boars were inoculated intranasally with pseudorabies virus to determine if microscopic testicular changes occurred as a result of infection. Testicular biopsies and semen samples were taken at two, four and six weeks postinoculation and the boars were castrated immediately after the last sample collection. Testicular samples and semen were cultured to determine if the virus was present. Pseudorabies virus was not isolated from the semen or testicular tissue. Virus was isolated from trige...

  5. Adolescent and adult risk factors for testicular cancer.

    Science.gov (United States)

    McGlynn, Katherine A; Trabert, Britton

    2012-06-01

    The incidence of testicular cancer has been increasing over the past several decades in many developed countries. The reasons for the increases are unknown because the risk factors for the disease are poorly understood. Some research suggests that in utero exposures, or those in early childhood, are likely to be important in determining an individual's level of risk. However, other research suggests that exposure to various factors in adolescence and adulthood is also linked to the development of testicular cancer. Of these, two adult occupational exposures-fire fighting and aircraft maintenance--and one environmental exposure (to organochlorine pesticides) are likely to be associated with increased risk of developing testicular cancer. By contrast, seven of the identified factors--diet, types of physical activity, military service, police work as well as exposure to ionizing radiation, electricity and acrylamide--are unlikely to increase the risk of developing testicular cancer. Finally, seven further exposures--to heat, polyvinyl chloride, nonionizing radiation, heavy metals, agricultural work, pesticides and polychlorinated biphenyls as well as marijuana use--require further study to determine their association with testicular cancer. PMID:22508459

  6. Ultrasonographic findings of torsed testicular appendages in prepubertal children

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Su Mi [Dept. of Radiology, SMG-SNU Boramae Medical Center, Seoul, (Korea, Republic of)

    2013-08-15

    To characterize the sonographic findings of torsed testicular appendages and to evaluate the sonographic findings in making erroneous diagnosis of epididymitis or torsion of testis in prepubertal children. From June 2010 to November 2012, we retrospectively analyzed the duplex sonography of fifteen children with torsion of testicular appendages. The presence or absence of the extratesticular nodule and secondary inflammatory changes were evaluated. Six patients had follow-up sonography and two patients underwent surgery. Sonography demonstrated the extratesticular nodule in 13 (87%) children. Four of these 13 children were misdiagnosed as epididymitis due to imperceptions of the nodule. Out of remaining two (13%) children without the nodule, one mimicked epididymitis and the other was misdiagnosed as torsion of testis. Secondary inflammatory changes included enlarged epididymis in 14 children (93%), scrotal wall edema in 11 (73%), hydrocele in 10 (67%), and enlarged testis in 3 (20%). Ultrasonographic findings of secondary inflammatory changes in the absence or imperception of the nodules for epididymo-testicular groove or epididymal head may suggest an erroneous diagnosis of epididymitis or torsion of testis in children with torsed testicular appendages. Meticulous evaluation for the nodule is important when differentiating the torsed testicular appendages from the two entities of prepubertal children.

  7. Testicular cancer: management challenges in an African developing country

    Scientific Electronic Library Online (English)

    F O, Ugwumba; A E, Aghaji.

    2010-07-01

    Full Text Available BACKGROUND: Advances in oncology have greatly improved the prognosis of testicular cancer. In developing countries, however, the outcome is still poor. PATIENTS AND METHODS: Twenty-four patients managed for testicular cancer at two centres (University of Nigeria Teaching Hospital, Enugu, Nigeria, an [...] d JAMA Urological Clinic, Enugu) between April 1984 and March 2003 were prospectively studied. Histopathological data were obtained in all cases. RESULTS: Peak age incidence was 20 - 29 years. Testicular swelling was the principal complaint in 23 patients. The mean interval between onset of symptoms and presentation was 5.3 months. Two patients (8.3%) presented with stage 1 disease, 7 (29.2%) with stage 2, 7 (29.2%) with stage 3, and 8 (33.3%) with stage 4. Seventy-five per cent of tumours were right-sided, and 25% were left-sided. Treatment consisted of radical orchidectomy in all patients and cisplatin-based chemotherapy and radiotherapy in some patients. One patient with a tumour in an intra-abdominal testis underwent laparotomy. The most common histological types were seminoma and embryonal carcinoma. A fifth of the patients died, while half were lost to follow-up. The mean follow-up period was 9 months. CONCLUSION: Morbidity and mortality of testicular cancer is high in developing countries. Late presentation, poverty, paucity of resources and the high cost of newer imaging modalities and treatment are major challenges to management. Better health funding and education regarding testicular self-examination is essential.

  8. Recurrent genomic rearrangements in primary testicular lymphoma.

    Science.gov (United States)

    Twa, David D W; Mottok, Anja; Chan, Fong Chun; Ben-Neriah, Susana; Woolcock, Bruce W; Tan, King L; Mungall, Andrew J; McDonald, Helen; Zhao, Yongjun; Lim, Raymond S; Nelson, Brad H; Milne, Katy; Shah, Sohrab P; Morin, Ryan D; Marra, Marco A; Scott, David W; Gascoyne, Randy D; Steidl, Christian

    2015-06-01

    Primary testicular diffuse large B cell lymphoma (PTL) is an aggressive malignancy that occurs in the immune-privileged anatomical site of the testis. We have previously shown that structural genomic rearrangements involving the MHC class II transactivator CIITA and programmed death ligands (PDLs) 1 and 2 are frequent across multiple B cell lymphoma entities. Specifically in PTL, we found rearrangements in the PDL locus by fluorescence in situ hybridization (FISH). However, breakpoint anatomy and rearrangement partners were undetermined, while CIITA rearrangements had not been reported previously in PTL. Here, we performed bacterial artificial chromosome capture sequencing on three archival, formalin-fixed, paraffin-embedded tissue biopsies, interrogating 20 known rearrangement hotspots in B cell lymphomas. We report novel CIITA, FOXP1 and PDL rearrangements involving IGHG4, FLJ45248, RFX3, SMARCA2 and SNX29. Moreover, we present immunohistochemistry data supporting the association between PDL rearrangements and increased protein expression. Finally, using FISH, we show that CIITA (8/82; 10%) and FOXP1 (5/74; 7%) rearrangements are recurrent in PTL. In summary, we describe rearrangement frequencies and novel rearrangement partners of the CIITA, FOXP1 and PDL loci at base-pair resolution in a rare, aggressive lymphoma. Our data suggest immune-checkpoint inhibitor therapy as a promising intervention for PTL patients harbouring PDL rearrangements. PMID:25712539

  9. Neonatal outcome and congenital malformations in children born after ICSI with testicular or epididymal sperm

    DEFF Research Database (Denmark)

    Fedder, J; Loft, A; Parner, Erik Thorlund; Rasmussen, S; Pinborg, A

    2013-01-01

    Does neonatal outcome including congenital malformations in children born after ICSI with epididymal and testicular sperm [testicular sperm extraction (TESE)/percutaneous epididymal sperm aspiration (PESA)/testicular sperm aspiration (TESA) (TPT)] differ from neonatal outcome in children born after ICSI with ejaculated sperm, IVF and natural conception (NC)?

  10. Study on the incidence of testicular and epididymal appendages in patients with cryptorchidism

    Directory of Open Access Journals (Sweden)

    Favorito Luciano A.

    2004-01-01

    Full Text Available OBJECTIVE: To study the incidence of testicular and epididymal appendages in patients with cryptorchidism. MATERIALS AND METHODS: We studied 65 patients with cryptorchidism, totalizing 83 testes and 40 patients who had prostate adenocarcinoma and hydrocele (control group, totalizing 55 testes. The following situations were analyzed: I absence of testicular and epididymal appendages, II presence of testicular appendage only, III presence of epididymal appendage, IV presence of testicular and epididymal appendage, V presence of 2 epididymal appendages and 1 testicular appendage and VI presence of paradidymis or vas aberrans of Haller. RESULTS: In patients with cryptorchidism we found testicular appendages in 23 cases (41.8%, epididymal appendages in 9 (16.3%, testicular and epididymal appendage in 8 (14.5%, 2 epididymal appendages and 1 testicular in 1 (1.8% and absence of appendages in 14 (25.4%. In the control group, we found testicular appendages in 29 (34.9%, epididymal appendages in 19 (22.8%, testicular and epididymal appendage in 7 (8.4%, and absence of appendages in 28 (33.7%, we did not find 2 epididymal appendages in this group, and none of the patients in the 2 groups presented paradidymis or vas aberrans of Haller. CONCLUSION: The occurrence of testicular and epididymal appendages is quite variable. There was no statistically significant difference in the incidence and distribution of the testicular and epididymal appendages between patients with cryptorchidism and those from the control group.

  11. Manejo multidisciplinario en la recidiva de carcinoma epidermoide de conducto auditivo externo. Presentación de un caso / Multidisciplinary handling of epidermoid carcinoma in the external auditory canal. Presentation of a case

    Scientific Electronic Library Online (English)

    Misleidy, Nápoles Morales; Orlando, Cruz García; Juan Carlos, Alfonso Coto; Pedro Pablo, Morales; Carlos F, Calderón Marín; Eduardo, Larrinaga Cortinas; Jorge Juan, Marinillo Guerrero; Betty, Santodomingo Reyna.

    2011-06-01

    Full Text Available Se presenta un paciente de 42 años con el diagnóstico de un carcinoma epidermoide bien diferenciado de conducto auditivo externo (CAE), diagnosticado en junio de 2008. El mismo recibió radioterapia como tratamiento con intención curativa a dosis radical 66 Gy. En enero de 2010, comenzó con aumento d [...] e volumen exagerado del conducto auditivo externo, discutiéndose en los servicios de Neurocirugía, Radioterapia y Cirugía Reconstructiva del Instituto Nacional de Oncología y Radiobiología. Al paciente se le realiza la exéresis total del tumor, una radioterapia intraoperatoria fraccionada con electrones (EIORT) y reconstrucción local con colgajo músculo cutáneo del pectoral mayor. El tratamiento resultó ser tolerado por el paciente aumentándole su expectativa y calidad de vida. Abstract in english A 42 year-old patient is presented with the diagnostic of an Epidermoid Carcinoma of the external auditory canal on June 2008. He had got a radical radiotherapy as treatment with a completely response but in January 2010 he return with the tumour in the same place. It was the reason to discuss this [...] patient in different department as Neurosurgery, Radiotherapy and Reconstructive Surgery. This patient received a total remove of the tumour, Intraoperative Radiotherapy with electron (EIORT) and a local reconstruction with mayor Pectoral Muscle. As Result the treatments were bear by the patient increasing his expectative and quality life.

  12. Quiste congénito de la valécula con alteraciones del peso: Caso clínico / Congenital vallecular cyst with weight disorders: Case report

    Scientific Electronic Library Online (English)

    Jhonder Xavier, Salazar Guilarte; José Mauri, Barbera.

    2013-04-01

    Full Text Available Los quistes de la valécula son un trastorno raro en los niños; el estridor es el síntoma más frecuente y la alteración del crecimiento, el más infrecuente. Se presenta el caso de un niño de 2 meses referido por la escasa ganancia ponderal desde su nacimiento, con antecedentes de atragantamiento al a [...] limentarse. No presentaba dificultad respiratoria, pero llamaba la atención la respiración bucal y la hiperextensión del cuello con lateralización hacia la derecha. El esofagograma mostró una masa hipofaríngea que desplazaba la laringe y reflujo del medio de contraste hacia el árbol bronquial. Por laringoscopia directa se resecó un quiste con técnica de marsupialización. La evolución fue favorable, sin recidivas, hasta el cuarto mes de seguimiento. Abstract in english Vallecula cysts are a rare condition in children, with stridor being the most common symptom and growth alterations the more uncommon. We present a 2 months-old child referred by low weight gain from birth, with a history of choking when feeding. He had no respiratory distress but struck mouth breat [...] hing and neck hyperextension with lateralization to the right. The esophagogram showed a mass displacing hypopharynx and larynx reflux of contrast into the bronchial tree. The cyst was resected by direct laryngoscopy with marsupialization technique. The outcome was favorable, without recurrence until the fourth month of monitoring.

  13. Reacción anafiláctica secundaria a quiste hidatídico hepático roto / Anaphylactic reaction secondary to a ruptured liver hydatid cyst. Case report

    Scientific Electronic Library Online (English)

    Juan L, Morales G; Claudio, Tapia C; César, Muñoz C; Eduardo, Otero V; Ricardo, Rebolledo R.

    2011-06-01

    Full Text Available La hidatidosis es una enfermedad parasitaria, zoonótica y endémica de gran importancia en nuestro país. El quiste hidatídico no complicado suele ser asintomático y es más frecuente encontrarlo en población adulta, siendo infrecuente su diagnóstico en la población pediátrica. Presentamos el caso de u [...] na paciente de 4 años de edad derivada al Servicio de Urgencia del Hospital de Chillán por cuadro de abdomen agudo posterior a trauma abdominal con manubrio de bicicleta, cuyo estudio tomográfico reveló la presencia de quiste hidatídico hepático y pulmonar rotos, que evoluciona con reacción anafiláctica secundaria. Abstract in english We report a four years old girl consulting in the emergency room for severe abdominal pain and vomiting secondary to a blunt abdominal trauma during a bicycling accident. A chest and abdomen CAT scan showed ruptured hydatid cysts in the lung and liver and free intraperitoneal fluid. During evolution [...] , the patient developed respiratory distress, bronchial obstruction, a papular exanthema and edema. Due to lack of response to steroids, she was operated excising the ruptured hepatic cyst and performing a peritoneal lavage. The patient had a good postoperative evolution. In a second surgical procedure, the lung cyst was excised. The patient is currently receiving albendazole and is asymptomatic after nine months of follow up.

  14. Reacción anafiláctica secundaria a quiste hidatídico hepático roto Anaphylactic reaction secondary to a ruptured liver hydatid cyst. Case report

    Directory of Open Access Journals (Sweden)

    Juan L Morales G

    2011-06-01

    Full Text Available La hidatidosis es una enfermedad parasitaria, zoonótica y endémica de gran importancia en nuestro país. El quiste hidatídico no complicado suele ser asintomático y es más frecuente encontrarlo en población adulta, siendo infrecuente su diagnóstico en la población pediátrica. Presentamos el caso de una paciente de 4 años de edad derivada al Servicio de Urgencia del Hospital de Chillán por cuadro de abdomen agudo posterior a trauma abdominal con manubrio de bicicleta, cuyo estudio tomográfico reveló la presencia de quiste hidatídico hepático y pulmonar rotos, que evoluciona con reacción anafiláctica secundaria.We report a four years old girl consulting in the emergency room for severe abdominal pain and vomiting secondary to a blunt abdominal trauma during a bicycling accident. A chest and abdomen CAT scan showed ruptured hydatid cysts in the lung and liver and free intraperitoneal fluid. During evolution, the patient developed respiratory distress, bronchial obstruction, a papular exanthema and edema. Due to lack of response to steroids, she was operated excising the ruptured hepatic cyst and performing a peritoneal lavage. The patient had a good postoperative evolution. In a second surgical procedure, the lung cyst was excised. The patient is currently receiving albendazole and is asymptomatic after nine months of follow up.

  15. Quiste gigante de ovario en una adolescente: presentación de un caso Giant ovarian cyst in an adolescent: a case report

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    Olimpia Contreras Leal

    2009-06-01

    Full Text Available Se trata de una adolescente de 13 años de edad con antecedentes de salud con menarquía a los 11 años y metrorragias frecuentes que acudió a consulta de Pediatría del Hospital Regional de Bata Litoral en la República de Guinea Ecuatorial por aumento de volumen del abdomen, específicamente del hemiabdomen derecho, es ínter consultada con Ginecología por sospecha de tumor de ovario, lo cual se corroboró por ultrasonografía. Se realiza intervención quirúrgica encontrándose quiste gigante de ovario derecho que pesó 6 kg del cual no tuvimos el diagnóstico histológico por no disponer de laboratorio de Anatomía Patológica, pero por las características macroscópicas se trató como un Quiste Seroso Simple, La paciente tuvo una evolución favorable.A 13- year-old girl is presented, having undergone a good health and menarche at 11 years old, she has had vaginal bleeding frequently, and came to Pediatrics Clinics at Bata Littoral Provincial Hospital in Equatorial Guinea with the Pediatrician. The main symptoms were abdominal volume increase, more specifically at right hemiabdomen and pain to deep palpation. This case was sent to the Gynecologist and an ovarian tumor was suspected, afterwards verified by the ultrasonographic study. The patients was referred to surgery, the final clinical diagnosis was Right Ovary Giant Cyst, weighing 6 kg. The histological diagnosis was not assessed because the lack of pathology lab in this country. Following the macroscopic features the tumor was treated as a Simple Serous Cyst. The patient had a favorable evolution.

  16. Leucoencefalopatía megalencefálica con quistes subcorticales (enfermedad de Van der Knaap) / Megalencephalic leukoencephalopathy with subcortical cysts (Van der Knapp disease)

    Scientific Electronic Library Online (English)

    Hugo Hernán, Abarca Barriga; María del Carmen, Castro Mujica; Bertha Elena, Gallardo Jugo.

    2013-03-01

    Full Text Available La leucoencefalopatía megalencefálica con quistes subcorticales es un desorden genético autosómico recesivo, debido a mutaciones en los genes megalencephalic leukoencephalopathy with subcortical cyst 1 (MLC1) o hepatocyte cell adhesion molecule (HEPACAM). Esta enfermedad de la sustancia blanca se ca [...] racteriza por macrocefalia de inicio temprano, deterioro motor y mental progresivo, ataxia y crisis epilépticas. La resonancia magnética nuclear muestra edema, compromiso difuso de la sustancia blanca y quistes subcorticales frontotemporales. Se presenta el primer caso reportado en Perú, de una niña con hallazgos clínicos y de la resonancia magnética nuclear típicos, con mutaciones heterocigotas en el gen MLC1. Abstract in english Megalencephalic leukoencephalopathy with subcortical cysts is a recessive autosomal genetic disorder, due to mutations in the gen megaloencephalic leukoencephalopathy with subcortical cyst 1 (MLC1) or hepatocyst cell adhesion molecule (HEPACAM). This white matter disease is characterized by macroenc [...] ephaly of early onset, progressive motor or mental deterioration, ataxia and epileptic crises. Magnetic resonance imaging shows edema, diffuse compromise of the white matter and frontotemporal subcortical cysts. Here is the first case reported in Peru; it is a girl with clinical findings and typical findings disclosed in the nuclear magnetic resonance imaging in addition to heterocygotic mutations in the gen MLC1.

  17. Metástases de coróide de origem testicular: relato de caso / Choroid metastasis of testicular primary site: case report

    Scientific Electronic Library Online (English)

    Marcos Rogério Mistro, Piccinin; João Augusto de, Almeida Jr.; Ricardo Dutra, Aydos; Daniel Cruz, Nogueira; Reinaldo Ferreira da, Silva.

    2006-12-01

    Full Text Available Descrição do caso de um paciente masculino de 22 anos de idade, cor parda, com decréscimo da acuidade visual em olho esquerdo e com diagnóstico de tumor testicular e metástases para pulmão e rim. Avaliação da evolução da lesão coroideana compatível com metástase ocular de tumor testicular por meio d [...] e exame oftalmológico e ecográfico. Houve resolução da lesão intra-ocular juntamente com melhora radiológica pulmonar após quimioterapia durante aproximadamente 4 meses de acompanhamento. Apesar da remissão da lesão ocular, o paciente faleceu por complicações decorrentes de metástase cerebral. Abordada na literatura como rara, não foi encontrado qualquer relato de caso sobre a metástase de coróide com sítio testicular, sendo esta, talvez, sua primeira descrição. Abstract in english Description of a male patient case, 22 years old, presenting visual acuity decrease in the left eye associated with the diagnosis of metastatic testicular tumor to lung and kidney. Evaluation of the evolution of a choroid lesion compatible with ocular metastasis of testis tumor through ophthalmologi [...] c and echographic examinations. There was resolution of the intraocular lesion together with lung radiologic improvement after chemotherapy during approximately 4 months of follow-up. In spite of the remission of the ocular lesion, the patient died due to complications of cerebral metastasis. Approached in the literature as rare, no report was found of a case of choroidal metastasis of a testicular site, this being, perhaps, its first description.

  18. Quiste pericárdico en un paciente con trasplante cardíaco: Descripción de un caso clínico / Pericardial Cyst in a Heart Transplant Patient: A Case Report

    Scientific Electronic Library Online (English)

    Pastor, Olaya; Eduardo, Contreras Zuniga.

    2010-02-01

    Full Text Available El quiste pericárdico es una entidad rara, de origen congénito, que acontece en el 7% de los casos de masas mediastínicas, localizado habitualmente en el lado derecho del pericardio y el mediastino anterior. En general, los pacientes evolucionan en forma asintomática, a excepción de los casos en los [...] que el quiste presenta una localización fuera de los sitios mencionados o en los que por su tamaño condiciona síntomas. En los sintomáticos, las manifestaciones dependen del sitio, la localización del quiste y los órganos involucrados. En esta presentación se describe el caso clínico de un paciente a quien se le realizó un trasplante cardíaco y posteriormente desarrolló un quiste pericárdico. Abstract in english Pericardial cysts are an uncommon congenital anomaly which represents 7% of mediastinal masses. Cysts frequently occur in the right cardiophrenic angle and in the anterior mediastinum. Although most pericardial cysts are asymptomatic, symptoms may develop in unusually located or large cysts. The cli [...] nical manifestations depend on the site of location and on the organs involved. We describe the case of a heart transplant patient who developed a pericardial cyst after transplantation.

  19. Lonidamine affects testicular steroid hormones in immature mice

    International Nuclear Information System (INIS)

    The effects on the hypothalamus-pituitary-testicular axis of the well-known antispermatogenic drug lonidamine (LND) has not been elucidated so far. In the present study, the possible changes of the testicular steroid hormones were evaluated in immature mice for a better characterization of the LND adverse effects both in its use as antitumoral agent and male contraceptive. Male CD1 mice were orally treated on postnatal day 28 (PND28) with LND single doses (0 or 100 mg/kg b.w.) and euthanized every 24 h from PND29 to PND32, on PND35 and on PND42 (1 and 2 weeks after the administration, respectively). Severe testicular effects were evidenced in the LND treated groups, including: a) significant testis weight increase, 24 h and 48 h after dosing; b) sperm head counts decrease (more than 50% of the control) on PND29-32; c) damage of the tubule morphology primarily on the Sertoli cell structure and germ cell exfoliation. All these reproductive endpoints were recovered on PND42. At the same time, a significant impairment of the testicular steroid balance was observed in the treated mice, as evidenced by the decrease of testosterone (T) and androstenedione (ADIONE) and the increase of 17OH-progesterone (17OH-P4) on the first days after dosing, while the testicular content of 17?-estradiol (E2) was unchanged. The hormonal balance was not completely restored afterwards, as levels of T, ADIONE and 17OH-P4 tended to be higher in the treated mice than in the controls, on PND35 and PND42. These data showed for the first time that LND affects intratesticular steroids in experimental animals. However further data are needed both to elucidate the mechanism responsible for the impairment of these metabolic pathways and to understand if the androgens decrease observed after LND administration could be partially involved in the testicular damage

  20. Gynecomastia Following Cytotoxic Therapy in a Patient with Testicular Cancer

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    Bar?? Ak?nc?

    2008-01-01

    Full Text Available Gynecomastia is the development of abnormal breast tissue in men. Relatively increased estrogen action on tissue level is believed to play a main role in the pathogenesis of the entity. Here, we describe a patient with painless gynecomastia presenting after cytotoxic chemotherapy for testicular cancer. Further investigations showed no evidence of disease progression, recurrence, or metastasis. We suggest that the clinicians should be aware that gynecomastia may follow cytotoxic chemotherapy for testicular cancer and does not reflect the return of malignancy. Turk Jem 2008; 12: 86-7

  1. Testicular Parameters and Morphological Characteristics of Testicular and Epididymal Spermatozoa of White Fulani Bulls in Nigeria Parámetros Testiculares y Características Morfológicas de los Espermatozoides Testicular y Epididimal de Toros Fulani Blancos en Nigeria

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    Matthew Olugbenga Oyeyemi

    2006-06-01

    Full Text Available Testicular parameters and morphological characteristics of testicular and epididymal spermatozoa of white Fulani bulls were study using twenty testicles. The objective was to study the normal testicular parameter and morphological changes during epididymal transit in the epididymis of white Fulani bulls. It was observed that there was reduction in the proportion of spermatozoa carrying the proximal cytoplasmic droplet (PCD along the epididymis as spermatozoa mature. There were more narrow head in the left (0.40 than the right epididymis (0.10. There was more bent normal tail (16.7 in the left epididymis than in right epididymis (13.0. The sperm cells having looped tails are higher in the left epididymis (caput, 4.90; corpus, 5.30; caudal 4.30 than the right epididymis (caput, 4.70; corpus, 3.20; caudal 5.10 despite the fact that the caudal epididymis in the right epididymis has a higher mean value. In this study the left testicle had more of the morphologically defective spermatozoa (12.96% than the right testicles (12.42%. The epididymal and testicular parameters were positively correlated (weight of epididymis, weight of estis and epididymis, length of epididymis, circumference of the testes and epididymis, (pSe estudiaron parámetros testiculares y características morfológicas de los espermatozoides testiculares y epididimarios en 20 testículos de toros Fulani blancos. El objetivo fue determinar parámetros testiculares normales y los cambios morfológicos de los espermatozoides durante su trayecto en el epidídimo. Se observó que hubo disminución de espermatozoides llevando droplet citoplasmático proximal (PCD en el epidídimo, durante la maduración espermática. Se presentaron más cabezas estrechas en el epidídimo izquierdo (0,40 que en el derecho (0,10. Hubo más espermatozoides con cola normal (16.7 en el epidídimo del lado izquierdo que en el lado derecho (13.0. Las células espermáticas tenían colas en loop en mayor cantidad en el epidídimo izquierdo (cabeza, 4.90; cuerpo, 5.30; cola 4.30 que en el lado derecho (cabeza, 4.70; cuerpo, 3.20; cola 5.10. Sin embargo, en la zona caudal del epidídimo derecho el valor promedio fue más alto. En este estudio, en el testículo izquierdo los espermatozoides presentaron más defectos morfológicos (12.96 que en el derecho (12.42. Entre los parámetros epididimarios y testiculares hubo correlación positiva (peso del epidídimo, peso de los testículos y epidídimos, longitud del epidídimo y circunferencias de los testículos y epidídimos p<0.05

  2. Testicular Parameters and Morphological Characteristics of Testicular and Epididymal Spermatozoa of White Fulani Bulls in Nigeria / Parámetros Testiculares y Características Morfológicas de los Espermatozoides Testicular y Epididimal de Toros Fulani Blancos en Nigeria

    Scientific Electronic Library Online (English)

    Matthew Olugbenga, Oyeyemi; Temilade Babalola, Eunice.

    2006-06-01

    Full Text Available Se estudiaron parámetros testiculares y características morfológicas de los espermatozoides testiculares y epididimarios en 20 testículos de toros Fulani blancos. El objetivo fue determinar parámetros testiculares normales y los cambios morfológicos de los espermatozoides durante su trayecto en el e [...] pidídimo. Se observó que hubo disminución de espermatozoides llevando droplet citoplasmático proximal (PCD) en el epidídimo, durante la maduración espermática. Se presentaron más cabezas estrechas en el epidídimo izquierdo (0,40) que en el derecho (0,10). Hubo más espermatozoides con cola normal (16.7) en el epidídimo del lado izquierdo que en el lado derecho (13.0). Las células espermáticas tenían colas en loop en mayor cantidad en el epidídimo izquierdo (cabeza, 4.90; cuerpo, 5.30; cola 4.30) que en el lado derecho (cabeza, 4.70; cuerpo, 3.20; cola 5.10). Sin embargo, en la zona caudal del epidídimo derecho el valor promedio fue más alto. En este estudio, en el testículo izquierdo los espermatozoides presentaron más defectos morfológicos (12.96) que en el derecho (12.42). Entre los parámetros epididimarios y testiculares hubo correlación positiva (peso del epidídimo, peso de los testículos y epidídimos, longitud del epidídimo y circunferencias de los testículos y epidídimos p Abstract in english Testicular parameters and morphological characteristics of testicular and epididymal spermatozoa of white Fulani bulls were study using twenty testicles. The objective was to study the normal testicular parameter and morphological changes during epididymal transit in the epididymis of white Fulani b [...] ulls. It was observed that there was reduction in the proportion of spermatozoa carrying the proximal cytoplasmic droplet (PCD) along the epididymis as spermatozoa mature. There were more narrow head in the left (0.40) than the right epididymis (0.10). There was more bent normal tail (16.7) in the left epididymis than in right epididymis (13.0). The sperm cells having looped tails are higher in the left epididymis (caput, 4.90; corpus, 5.30; caudal 4.30) than the right epididymis (caput, 4.70; corpus, 3.20; caudal 5.10) despite the fact that the caudal epididymis in the right epididymis has a higher mean value. In this study the left testicle had more of the morphologically defective spermatozoa (12.96%) than the right testicles (12.42%). The epididymal and testicular parameters were positively correlated (weight of epididymis, weight of estis and epididymis, length of epididymis, circumference of the testes and epididymis, (p

  3. Combined radiotherapy and chemotherapy with cyclophosphamide, adriamycin, methotrexate, procarbazine (camp) in 64 consecutive patients with epidermoid bronchogenic carcinoma, limited disease: a prospective study

    International Nuclear Information System (INIS)

    Sixty-four consecutive patients with inoperable epidermoid bronchogenic carcinoma (limited disease) were treated with radiotherapy to the primary and nodal areas and combination chemotherapy with cyclophosphamide, adriamycin, methotrexate and procarbazine. The overall response rate (CR + PR) to combined treatment was 62%. The median survival time was 12.7 months. The toxicity was acceptable and no treatment-related death occurred

  4. Quiste aracnoideo espinal epidural postraumático: presentación de un caso / Postraumatic epidural arachnoid spinal cyst: case report

    Scientific Electronic Library Online (English)

    O., Hernández-León; F.R., Pérez-Nogueira; N., Corrales.

    2011-06-01

    Full Text Available Introducción. Los quistes aracnoideos extradurales espinales son lesiones poco frecuentes. Clínicamente se caracterizan por un cuadro mielopático progresivo, asociado o no a crisis radiculares. Para su diagnóstico radiológico las técnicas de resonancia magnética actuales posibilitan definirlos adecu [...] adamente y conocer su localización topográfica. Los antecedentes patológicos del paciente son esenciales para establecer se etiología encontrándose en muchos casos una historia de trauma espinal, cirugía y menos frecuentemente anomalías congénitas asociadas. El tratamiento en la mayoría de los casos es quirúrgico. Caso clínico. Presentamos el caso de un paciente de 35 años con antecedentes de una hemisección medular dorsal por arma blanca hace dos años. Evolutivamente se deterioran sus funciones motoras presentándose con una paraparesia espástica. Los estudios radiológicos mostraron la presencia de la lesión quística extradural comprimiendo el cordón medular a nivel dorsal (D3-D4). Se realizó cirugía descompresiva y se identificó un desgarro meníngeo a ese nivel que fue suturado. La evolución postoperatoria fue satisfactoria. Conclusiones. El tratamiento quirúrgico efectivo de estas lesiones está dado por la detección del defecto meníngeo y su cierre. Abstract in english Introduction. Extradural arachnoid spinal cysts are unfrequent lesions that are associated with spinal trauma, surgery and less frequently with congenital anomalies. The clinical manifestations are similar to those seen with other compressive spinal cord lesions. Magnetic resonance techniques allow [...] to diagnose correctly this pathology and to define its thopographic situation. The pathologic history of the patient is essencial to establish the ethiology. Surgery is the elective treatment in most cases. Clinical case. The patient is a 35 years old man who has a medical history of penetrating spinal trauma two years ago. In that instance he suffered an unilateral spinal cord section at D2-D3 level with the corresponding Brown Sequard syndrome. A small wound was detected at the skin dorsal level and it was closed without difficulties. At the beginning, he improved his motor right leg function with rehabilitation and vitamins. After two years of good recovery he came to our hospital suffering a neurological deterioration of six months of evolution. The physical examination revealed an spastic paraparesis. Magnetic resonance was performed demonstrating a cystic extradural collection compressing the spinal cord at D3-D4 level. Surgical decompressive treatment allowed to excise the cyst and it was possible to define a dural tear that was closed successfully. The outcome was good with restoration of the initial motor function that he had after the spinal trauma. Conclusions. Surgical management of postraumatic epidural arachnoid spinal cyst allows to detect the meningeal tear and to close it, which is highly effective on these kinds of lesions.

  5. Leydig-cell function in children after direct testicular irradiation for acute lymphoblastic leukemia

    International Nuclear Information System (INIS)

    To assess the effect of testicular irradiation on testicular endocrine function, we studied 12 boys with acute lymphoblastic leukemia who had been treated with direct testicular irradiation 10 months to 8 1/2 years earlier. Insufficient Leydig-cell function, manifested by a low response of plasma testosterone to chorionic gonadotropin or an increased basal level of plasma luteinizing hormone (or both), was observed in 10 patients, 7 of whom were pubertal. Two of these patients had a compensated testicular endocrine insufficiency with only high plasma concentrations of luteinizing hormone. Testosterone secretion was severely impaired in three pubertal boys studied more than four years after testicular irradiation. A diminished testicular volume indicating tubular atrophy was found in all pubertal patients, including three who had not received cyclophosphamide or cytarabine. These data indicate that testosterone insufficiency is a frequent complication of testicular irradiation, although some patients continue to have Leydig-cell activity for several years after therapy

  6. HISTOLOGIA TESTICULAR HUMANA COMPARADA, ADULTO JOVEN Y SENIL / HUMAN TESTICULAR HISTOLOGY IN YOUNG AND SENILE MEN

    Scientific Electronic Library Online (English)

    Héctor, Rodríguez; Paulina, Salazar; Nadia, Schmidt; Patricia, Torres; Enrique, Ossandón.

    Full Text Available [...] Abstract in english In general, sperm production decreases with advanced age in men. Therefore the present work compares the histology and cellularity of aging human testis with that of a young adult. Gonads from three patients 69 years old and testis from a young subject (aged 25 years) were examined after histologic [...] al standard techniques (PAS-Haematoxyline). Histological, morphometric and cell counting analyses of testicular sections revealed that the seminiferous tubules of senile patients were of smaller diameter, with lower seminiferous epithelium, incomplete germ cell line and vacuolization of the epithelium. Sertoli cells showed a market quantitative decrease, similar to the spermatogonial and primary spermatocyte population. It is possible to postulated that in the senile individues there is a programmed damage of seminiferous epithelial cells that may result in lowered sperm production

  7. Regulación inmuno-testicular y citocinas / Immune-testicular regulation and cytokines

    Scientific Electronic Library Online (English)

    Giovanny, Vivas-A; Jesús, Lozano-H; Judith, Velasco.

    2007-03-01

    Full Text Available La patogénesis de la infertilidad masculina se puede reflejar en una alteración de la espermatogénesis, causada por cáncer testicular, aplasia de las células germinales, varicocele, factores ambientales o defecto en el transporte de los espermatozoides, entre otros. En general, un 48% de hombres cur [...] sa con esterilidad sin causa aparente. Durante mucho tiempo, el tracto reproductor masculino y el sistema inmunológico han sido estudiados como sistemas diferentes e independientes. Sin embargo, en las dos últimas décadas se ha despertado un particular interés por la interacción de ambos sistemas en la infertilidad masculina, con énfasis en la evaluación de anticuerpos antiespermáticos como causa común de infertilidad. Además, la inflamación debida a infecciones genitales o sistémicas puede causar alteraciones en la función testicular. El reconocimiento de los antígenos intratesticulares, provoca la producción de anticuerpos por parte de los linfocitos B. Luego, el sistema inmunológico induce una respuesta celular, mediante la secreción de citoquinas, activación del complemento y activación de los linfocitos T. En la presente revisión se examinarán los componentes y el mecanismo de respuesta del sistema inmunológico, la organización del testículo como órgano reproductor, los mediadores de la respuesta inmunológica: interleucina-1 (IL-1), IL-6 Factor Inhibidor de la Leucemia, Factor de necrosis tumoral ?, Molécula FasL (CD95L) y Fas (CD95), Factor inhibitorio de la migración de macrófagos, Factor Estimulador de las Colonias de Fagocitos Mononucleares y Factor Estimulador de las Colonias de Granulocitos/macrófagos, así como Factor de Células Madres, Interferón, Factor de Transformación y Crecimiento ? y activinas. Abstract in english The pathogenesis of male infertility can be reflected in alterations of spermatogenesis caused by testicular cancer, aplasia of the germinal cells, varicocele, environmental factors or defect in the transport of the sperms, among others. In general, 48% of men suffer unexplained infertility. During [...] a long time, the masculine reproductive tract and the immune system have been studied as different and independent systems. However, in the last two decades a particular interest has arisen in the interaction of both systems on masculine infertility, in particular in the evaluation of antisperm antibodies as a common cause of infertility. Also, the inflammation due to genital or systemic infections can cause alterations in the testicular function. The recognition of intratesticular antigens provokes the production of antibodies by B lymphocytes. Then, the immune system induces a cellular response, by cytokines secretion, activation of complement and T lymphocytes activation. In this review the components and the immune system response mechanism, the organization of the testicle as a reproductive organ and the mediators of the immunologic response will be examined: interleukin-1 (IL-1), IL-6, leukaemia Inhibitory factor, tumor necrosis factor- ?, the molecule FasL (CD95L) and Fas (CD95), macrophage migration-inhibitory factor, mononuclear phagocyte colony stimulating factor, Granulocyte/macrophage colony stimulating factor, as well as stem cell factor, interferon, transforming growth factor B and activins.

  8. P53 overexpression in epidermoid carcinoma of the head and neck

    Scientific Electronic Library Online (English)

    Angela Flavia, Logullo; Luiz Paulo, Kowalski; Sueli, Nonogaki; Roberto E. V., Miguel; Humberto, Torloni; Ricardo R., Brentani.

    1997-02-01

    Full Text Available A teoria de campo de cancerização em neoplasias de cabeça e pescoço (CP) reflete a complexa oncogênese que ocorre nesta região. Os mecanismos a nível molecular que controlam a proliferação celular em Carcinomas epidermóides (CEC) de vias aerodigestivas superiores ainda são pouco conhecidos. Mutações [...] no p53 são as alterações genéticas mais encontradas em CEC de CP e parecem contribuir ativamente em seu processo carcinogênico como gene supressor de tumor e a sua associação com tabaco. O objetivo deste trabalho é analisar a expressão da proteína p53 em carcinoma epidermóide de cabeça e pescoço por meio de reação imunohistoquimica e sua correlação com outros fatores prognósticos. O estudo inclui 63 casos consecutivos de CEC, não tratados previamente. Espécimes de tumor e de mucosa normal adjacente foram colhidos durante o ato cirúrgico e submetidos a reação imunohistoquímica para avaliação da expressão do anticorpo anti-proteína p53 (M7001 DAKO AVS, Denmark Inc.) Não houve significância entre os dados anatomo-clínicos e demográficos, presença de metastases linfonodais e a expressão de p53 no tumor ou na mucosa adjacente normal. A localização do tumor na laringe apresentou correlação estatistica significativa com a expressão da p53 . A graduação histológica, separada em graus I e ll, e III e IV apresentou correlação com a expressão de p53 significante ( p=0,025). Conclusões: 1-No material estudado proveniente de 63 casos de CEC de cabeça e pescoço encontramos 48% de superexpressão de p53 imunohistoquimicamente detectável, índice compatível com os demais relatados na literatura; 2-Não encontramos relação entre os dados demográficos do paciente e a expressão de p53 no tumor e na mucosa normal adjacente; 3- O achado de superexpressão de p53 mais freqüente em Material de CEC de laringe foi estatisticamente significativo. 4-A presença de 12 casos com superexpressão de p53 na mucosa normal adjacente e com tumor p53 negativo esta de acordo com a teoria de cancerização de campo. O seguimento desta série por maior tempo possibilitará uma melhor análise destes valores. Abstract in english The theory of field cancerization in tumors of the head and neck reflects the complex oncogenesis that occurs in this region. The mechanisms that control cell proliferation at the molecular level in epidermoid carcinomas (ECs) of the upper aerodigestive tract are still unclear. Mutations in p53 are [...] the genetic alterations most often detected in ECs of the head and neck and seem to contribute actively to the carcinogenic process triggered by p53 as a tumor-suppressor gene and to its association with tobacco. The objective of the present study was to investigate the expression of p53 protein in epidermoid head and neck carcinomas by immunohistochemistry and its immunohistochemical correlation with other prognostic factors. The study was conducted on 63 consecutive ECs cases not submitted to previous treatment. Specimens of the tumor and of the normal adjacent mucosa were collected during surgery and submitted to immunohistochemical reaction for the determination of the expression of anti-protein p53 antibody (M7001 DAKO A/S, Denmark). Anatomo-clinical and demographic data were not significantly correlated with the presence of lymph node metastases or p53 expression in the tumor or in the adjacent normal mucosa. Tumor localization in the larynx was significantly correlated with p53 expression. Histological grading as grades I, II, Ill and IV was correlated with significant p53 expression (p = 0.025). Conclusions: 1) in the studied material obtained from 63 cases of head and neck ECs, we detected a 48 percent rate of immunohistochemically detectable p53 overexpression; 2) we did not detect a relationship between demographic patient data and p53 expression in the tumor or in the normal adjacent mucosa; 3) p53 overexpression was significantly more frequent in ECs material from the larynx; and 4) The presence of 12 cases with p53 overexpression in t

  9. Second to fourth digit ratio: a predictor of adult testicular volume.

    Science.gov (United States)

    Oh, J K; Kim, K T; Yoon, S J; Kim, S W; Kim, T B

    2014-11-01

    It has been suggested that second to fourth digit ratio (digit ratio) may correlate with male reproductive system function or disorders. This hypothesis is based on finding that the Hox genes control finger development and differentiation of the genital bud during embryogenesis. Thus, we investigated the association between digit ratio and adult testicular volume. A total of 172 Korean men (aged 20-69 years) hospitalized for urological surgery were prospectively enrolled. Patients with conditions known to strongly influence testicular volume were excluded. Before determining testicular volume, the lengths of the second and fourth digits of the right hand were measured by a single investigator using a digital vernier calliper. Using orchidometry, the testes were measured by an experienced urologist who had no information about the patient's digit ratio. To identify the independent predictive factors influencing testicular volume, univariate and multivariate analyses were performed using linear regression models. Age, height, serum testosterone and free testosterone level were not correlated with testicular volume. Digit ratio, along with weight, was significantly correlated with testicular volume (right testicular volume: r = -0.185, p = 0.015; left testicular volume: r = -0.193, p = 0.011; total testicular volume: r = -0.198, p = 0.009). Multivariate analysis using linear regression models showed that only digit ratio was the independent factor to predict all (right, left and total) testicular volumes (right testicular volume: ? = -0.174, p = 0.023; left testicular volume: ? = -0.181, p = 0.017; total testicular volume: ? = -0.185, p = 0.014). Our findings demonstrated that digit ratio is negatively associated with adult testicular volume. This means that men with a higher digit ratio may be more likely to have smaller testis compared to those with a lower digit ratio. PMID:25116409

  10. Cisto assintomático em região da valécula: relato de caso / Asymptomatic vallecular cyst: case report / Quiste valecular asintomático: relato de caso

    Scientific Electronic Library Online (English)

    Yucel, Yuce; Sennur, Uzun; Ulku, Aypar.

    2013-10-01

    Full Text Available Paciente do sexo masculino, 56 anos, apresentou-se para excisão de glioblastoma intracraniano multiforme. Após ser rotineiramente monitorado, o paciente foi pré-oxigenado. Anestesia e paralisia foram induzidas com propofol (200 mg), fentanil (50 µg) e vecurônio (9 mg). Laringoscopia direta com lâmin [...] a Macintosh número 3 revelou um cisto pedunculado de 2x2 cm, que surgia do lado direito da valécula e impedia a intubação endotraqueal. Enquanto o paciente permanecia anestesiado, consultamos rapidamente um otorrinolaringologista e o cisto foi aspirado por uma seringa com agulha de calibre 22G sob laringoscopia direta. Aspiramos 10 cc de líquido. Intubação traqueal foi feita em seguida sem intercorrências com sonda de 9,0 aramada e com balão. Uma opção para a intubação com fibra óptica pode ser a aspiração cuidadosa do cisto para facilitar a intubação. Abstract in spanish Un paciente del sexo masculino, de 56 años, llegó para una resección de glioblastoma intracraneal multiforme. Posteriormente a la rutina de monitorización, el paciente fue pre-oxigenado. La anestesia y la parálisis se indujeron con propofol (200 mg), fentanilo (50 µg) y vecuronio (9 mg). La laringos [...] copia directa con lámina 3 Macintosh arrojó un quiste pedunculado de 2x2 cm que surgía al lado derecho de la valécula e impedía la intubación endotraqueal. Mientras el paciente permanecía anestesiado, consultamos rápidamente un otorrinolaringólogo y el quiste fue aspirado por una jeringa con una aguja calibre 22G bajo laringoscopia directa. Aspiramos 10 cc de líquido. La intubación traqueal se hizo enseguida sin intercurrencias con una sonda de 9,0 y un alambre en espiral y con balón. Una opción para la intubación con fibra óptica puede ser la aspiración cuidadosa del quiste para facilitar la intubación. Abstract in english A 56-year-old man presented himself for an intracranial glioblastoma multiforme excision. After being routinely monitored, he was preoxygenated. We induced anesthesia and paralysis with 200 mg propofol, 50 µg fentanyl and 9 mg vecuronium. Direct laryngoscopy with a Macintosh 3 blade revealed a 2x2 c [...] m cyst, pedunculated, arising from the right side of the vallecula preventing the endotracheal intubation. While the patient remained anesthetized, we urgently consulted an otolaryngologist and aspirated the cyst with a 22-gauge needle and syringe under direct laryngoscopy. We aspirated 10 cc of liquid content. This was followed by an uneventful tracheal intubation with a 9.0 enforced spiral cuffed tube. An alternative to fiberoptic intubation may be careful cyst aspiration to facilitate the intubation.

  11. An infant with testicular torsion in the inguinal canal

    Energy Technology Data Exchange (ETDEWEB)

    Candocia, Fabian J.; Sack-Solomon, Kathryn [Jacobi Medical Center, Albert Einstein College of Medicine, 1400 Pelham Parkway, Room 4N15, Bronx, NY 10461 (United States)

    2003-10-01

    We report a case of testicular torsion in the left inguinal canal of a 7 month old with a history of cryptorchism and no evidence of neuromuscular disease. We discuss the pathophysiological mechanisms, sonographic findings, and treatment of this rare entity. (orig.)

  12. An infant with testicular torsion in the inguinal canal

    International Nuclear Information System (INIS)

    We report a case of testicular torsion in the left inguinal canal of a 7 month old with a history of cryptorchism and no evidence of neuromuscular disease. We discuss the pathophysiological mechanisms, sonographic findings, and treatment of this rare entity. (orig.)

  13. Metabolic fingerprints in testicular biopsies from type 1 diabetic patients.

    Science.gov (United States)

    Alves, Marco G; Martins, Ana D; Moreira, Paula I; Carvalho, Rui A; Sousa, Mário; Barros, Alberto; Silva, Joaquina; Pinto, Soraia; Simões, Teresinha; Oliveira, Pedro Fontes

    2015-11-01

    Diabetes mellitus (DM) is a metabolic disease that has grown to pandemic proportions. Recent reports have highlighted the effect of DM on male reproductive function. Here, we hypothesize that testicular metabolism is altered in type 1 diabetic (T1D) men seeking fertility treatment. We propose to determine some metabolic fingerprints in testicular biopsies of diabetic patients. For that, testicular tissue from five normal and five type 1 diabetic men was analyzed by high-resolution magic-angle spinning (HR-MAS) nuclear magnetic resonance (NMR) spectroscopy. mRNA and protein expression of glucose transporters and glycolysis-related enzymes were also evaluated. Our results show that testes from diabetic men presented decreased levels of lactate, alanine, citrate and creatine. The mRNA levels of glucose transporter 1 (GLUT1) and phosphofructokinase 1 (PFK1) were decreased in testes from diabetic men but only GLUT3 presented decreased mRNA and protein levels. Lactate dehydrogenase (LDH) and glutamate pyruvate transaminase (GPT) protein levels were also found to be decreased in testes from diabetic men. Overall, our results show that T1D alters glycolysis-related transporters and enzymes, compromising lactate content in the testes. Moreover, testicular creatine content was severely depressed in T1D men. Since lactate and creatine are essential for germ cells development and support, the data discussed here open new insights into the molecular mechanism by which DM promotes subfertility/infertility in human males. PMID:26051285

  14. Influence of large testicular dose on neuroendocrine function in rats

    International Nuclear Information System (INIS)

    In present study, the changes of hypothalamic endogenous opiate peptides and the endocrine function of pituitary and testes were observed at 1, 23, 63 and 97 days after exposure of testes to 10 Gy X-rays in male Wistar rats to attempt to clarify the neuroendocrine effect of ionizing radiation and its mechanism. One day after irradiation, hypothalamic ?-endorphin (?-EP) content increased significantly, but serum luteinizing hormone (LH), follicle-stimulating hormone (FSH) and testosterone (TS) and cAMP content in tests were lowered in varying degrees. Twenty three days after irradiation, hypothalamic ?-EP content decreased, while serum LH, FSH, TS and testicular cAMP content increased very significantly. Sixty three days after irradiation, the level of hypothalamic ?-EP still was the same as that at 23 days after irradiation, hypothalamic leu-enkephalin (L-Enk) content decreased significantly, serum LH and FSH levels still continued to increase up, while serum TS and testicular cAMP contents declined very significantly. Ninety seven days after irradiation, serum LH and FSH levels returned to lower, serum TS and testicular cAMP content still continued to decrease, and in testicular tissue, serious lesion occurred

  15. Testicular seminoma in a patient with pineal germinoma.

    OpenAIRE

    Peat, D. S.; Trowell, J E

    1994-01-01

    A case is reported of a 30 year old man with a testicular seminoma. He had presented 16 years previously with a pineal germinoma, followed two years later by intracranial metastases. This is an unusual occurrence of double pathology in the germ cell line.

  16. Testicular perfusion after standing laparoscopic peritoneal flap hernioplasty in stallions.

    Science.gov (United States)

    Gracia-Calvo, L A; Duque, J; Balao da Silva, C; Ezquerra, J; Ortega-Ferrusola, C

    2015-09-15

    Acquired inguinal herniation is a very common condition in stallions, usually leading to unilateral or bilateral castration to prevent future recurrence. Recently, several surgical techniques such as the standing laparoscopic peritoneal flap hernioplasty (SLPFH) have been developed to avoid herniation recurrence and also preserve the breeding activity of high economic value stallions. However, studies on SLPFH lack more comprehensive and systematic data about reproductive-related adverse effects and outcomes. The aim of this study was to evaluate whether SLPFH of the internal inguinal rings produces changes in the testicular blood flow in a 1-year follow-up. For that purpose, six healthy stallions were used and testicular blood flow was assessed before, 3, 6, and 12 months (T0, T3, T6, and T12) after the procedure. Blood flow was evaluated ultrasonographically, using the pulsed-wave color Doppler mode. Peak systolic velocity, end-diastolic velocity, the time-averaged maximum velocity, and the derived indexes (resistive index) and pulsatility index) of the testicular artery were measured in two localizations: in the spermatic cord and on the caudal epididymal edge of the testicle. On the spermatic cord, the peak systolic velocity of the testicular artery increased significantly at T12. However, on the epididymal edge location of the artery, the pulsatility and resistive indexes were decreased at T12 (P effect on sperm production during this time. The spectral Doppler ultrasound is a useful tool to asses the testicular perfusion after reproductive surgical procedure and provides information which anticipates vascular supply compromise of the stallion testicles. PMID:26116054

  17. Type II intrapancreatic choledochal malignant cyst in adults: duodenopancreatectomy / Quiste de colédoco tipo II intrapancreático del adulto malignizado: duodenopancreatectomía

    Scientific Electronic Library Online (English)

    Miguel Ángel, Jiménez-Ballester; Victoriano, Soria-Aledo; Juan Gervasio, Martín-Lorenzo; José Ramón, Olalla-Muñoz; Alberto, Giménez-Bascuñana; Eduardo, Alcaraz-Mateos; José Luis, Aguayo-Albasini.

    2014-03-01

    Full Text Available Presentamos el caso de una paciente de 62 años que ingresó de urgencias por pancreatitis aguda leve. En las pruebas de imagen se observó una lesión sólido-quística en la cabeza de páncreas comunicante con la vía biliar distal, y se diagnosticó quiste de colédoco tipo II de Todani con degeneración ne [...] oplásica en su interior confirmada tras una biopsia por punción en una ecoendoscopia. La paciente fue tratada con una duodenopancreatectomía cefálica con intención curativa. Abstract in english A 62-year-old female patient was admitted for abdominal pain and vomiting. Imaging tests revealed a solid-cystic lesion at the head of the pancreas communicating with the distal bile duct. A Todani type II choledochal cyst was diagnosed with neoplastic degeneration after cytological diagnosis with e [...] ndoscopic ultrasound-guided puncture. The patient was treated with a cephalic duodenopancreatectomy with curative intention.

  18. Quiste gigante de uraco en el adulto / The giant cyst of urachus present in the adult patient

    Scientific Electronic Library Online (English)

    Radamés Isaac, Adefna Pérez; Armando, Leal Mursulí; Francoise, Izquierdo Lara; Nélida, Ramos Díaz; Juan, Castellanos González; Juan Francisco, Rodríguez Reyes.

    2009-06-01

    Full Text Available El quiste de uraco es una anomalía congénita que se incluye entre las lesiones originadas por la persistencia total o parcial de restos de este conducto. Se diagnostica principalmente durante la infancia y su complicación principal es la infección. Presentamos el caso de adulto con una tumoración ab [...] dominal gigante quística, diagnosticada como de origen uracal y tratada quirúrgicamente. Se hace una revisión del tema, con énfasis en los aspectos principales del tratamiento de la enfermedad. Abstract in english The urachus cyst is a congenital anomaly included among lesions originated by local or partial resistance of this duct. Is mainly diagnosed during infancy and its main complication is the infection. Authors present the case of an adult patient presenting with a cystic giant abdominal tumor, diagnose [...] d as of urachal origin and treated by surgery. This matter is reviewed emphasizing on main features of disease treatment.

  19. Resección del quiste tirogloso con preservación del hueso hioides / Resection of thyroglossal cyst with preservation of the hyoid bone

    Scientific Electronic Library Online (English)

    Gabriel, Sánchez; Elkin, Cabrera.

    2014-03-01

    Full Text Available Introducción. El quiste del conducto tirogloso representa la lesión congénita más frecuente del cuello, con una incidencia de 7 % de la población general. La presentación típica consiste en una masa en la línea media, entre el foramen ciego y la glándula tiroides, que asciende con la deglución o pro [...] trusión de la lengua. Tradicionalmente, se ha recomendado la remoción del quiste mediante el procedimiento de Sistrunk. Se describe una modificación de la técnica quirúrgica, preservando el cuerpo del hioides. El objetivo del presente estudio fue evaluar la frecuencia de complicaciones perioperatorias y de recidiva después del procedimiento quirúrgico modificado. Materiales y métodos. Se hizo un análisis retrospectivo de una cohorte de pacientes sometidos entre marzo de 2003 y marzo de 2011 a la resección quirúrgica del quiste del conducto tirogloso con el procedimiento modificado. Las intervenciones fueron practicadas por un cirujano de cabeza y cuello de la Fundación Cardioinfantil (Bogotá). Resultados. En el estudio se incluyeron 43 pacientes que cumplían los criterios de inclusión. La mediana de seguimiento fue de 11 meses y la tasa de complicaciones fue 6,9 % (n=3). Se presentaron dos granulomas a cuerpo extraño y un mucocele, este último considerado como una recidiva (2,3 %). Discusión. En el presente estudio no se encontró un incremento en la frecuencia de complicaciones perioperatorias cuando se reseca el quiste del conducto tirogloso con la técnica modificada. La recurrencia de la enfermedad está en el rango de lo reportado en la literatura científica, por lo que consideramos que el procedimiento quirúrgico propuesto puede ser una opción segura y viable. Abstract in english Introduction: Thyroglossal duct cyst is the most common congenital anomaly of the neck, with an overall incidence of 7%. The typical presentation is a mass in the midline between the foramen cecum and the thyroid gland, which moves with swallowing or protrusion of the tongue. Traditionally it has be [...] en recommended the removal of the cyst by the Sistrunk procedure. The authors describe a modified surgical technique that preserves the hyoid bone. The aim of our study was to evaluate the rate of perioperative complications and recurrences after this modified surgical procedure. Materials and methods: We conducted a retrospective analysis of a cohort patients undergoing resection of thyroglossal duct cyst with the modified surgical procedure between March 2003 and March 2011. Surgery was performed by a head and neck surgeon of Foundation Cardioinfantil, Bogotá. Results: 43 patients who met the inclusion criteria were included in the study. Median follow-up was 11 months and the rate of complications was 6.9% (n = 3). There were 2 foreign body granulomas and one mucocele, which was considered a recurrence (2.3%). Discussion: We did not find an increase in the rate of perioperative complications with the modified surgical technique. Recurrence of the disease is similar to the data reported in the literature and we believe that the proposed surgical procedure can be a safe and viable option.

  20. Quistes de los maxilares en niños: Un analisis clínico / Cystic lesions of the jaws in children: A clinic analysis

    Scientific Electronic Library Online (English)

    Gustavo, Pina Godoy; Éricka Janine, Dantas da Silveira; Manuel Antonio, Gordón-Núñez; Lélia Maria, Guedes Queiroz; Daniela, Medeiros Dantas Gomes.

    2007-12-01

    Full Text Available Objetivo: Realizar uma avaliação epidemiológica dos cistos odontogênicos em pacientes de 0 a 14 años de edad, verificando quais são as lesões de mayor incidência entre estas idades. Métodos: Foram avaliadas 100 fichas histopatológicas de lesões diagnosticadas como cistos de natureza odontogênica, en [...] fatizando as características clínicas (gênero, idade, tipo de lesão cística, localização anatômica e tamanho da lesão) e radiográficas. Resultados: Foi observado que o gênero masculino, com idade média de 9,78 anos, assim como as regiões posterior de mandíbula e anterior da maxila foram mais comprometidos. O cisto dentígero foi a lesão mais comum, seguida d cisto radicular. Observou-se, além disso, que na amostra avaliada o aspecto radiográfico unilocular e as lesões assintomáticas foram as mais freqüentes. Conclusões: Foi concluído que é muito importante realizar este tipo de estudos, uma vez que, através deles podemos conhecer a freqüência e incidência de diversas lesões, principalmente em pacientes pediátricos, nos quais pouco se conhece sobre a prevalência das lesões císticas dos maxilares. Abstract in spanish Objetivo: Realizar una evaluación epidemiológica de los quistes odontogénicos en pacientes de 0 a 14 años de edad, verificando cuales son las lesiones de mayor incidencia entre estas edades. Métodos: Fueron evaluadas 100 fichas histopatológicas de lesiones diagnosticadas como quistes de naturaleza o [...] dontogénica, enfatizando las características clínicas (género, edad, tipo de lesión quística, localización anatómica y tamaño de la lesión) y radiográficas. Resultados: Fue observado que el género masculino, con edad media de 9,78 años, así como las regiones posterior de mandíbula y anterior de la maxila fueron más comprometidos. El quiste dentígero fue la lesión más común, seguida del quiste radicular. Se observó además, que en la muestra evaluada el aspecto radiográfico unilocular y las lesiones asintomáticas fueron las más frecuentes. Conclusiones: Se concluyó que es muy importante realizar éste tipo de estudios, una vez que, a través de ellos podemos conocer la frecuencia e incidencia de diversas lesiones, principalmente en pacientes pediátricos, en los cuales poco se conoce sobre la prevalencia de las lesiones quísticas de los maxilares. Abstract in english Objective: To realize an epidemiologic survey of odontogenic cysts in patients from 0 to 14 years old in order to find out the most prevalent lesions of each age period. Methods: 100 histopathologic files of lesions diagnosed as cysts of odontogenic origin were retrieved emphasing their clinic (cyst [...] ic lesion pattern, gender, age, anatomical site and lesion lenght) and radiographic features, which the surgical specimens were forwarded for the Oral Pathology Service of UFRN. Results: It could be identified that either the male gender, with an age average of 9,78 years, or the mandible posterior and the anterior maxilla region were more involved. Dentigerous cyst was the most prevalent lesions, followed by the radicular cyst. Moreover, a unilocular radiolucence and asymptomatic lesions were more common in the sample. Conclusions: To sum up, it can be infered the outstanding relevance of studies like the present since that it is through than that it can be reached the knownlodge of the frequence and incidence of several lesions, especially in paediatric patients inasmuch as the few knownlodge of the cystic lesion prevalence in their jaws.

  1. Quiste gigante de ovario y mioma uterino. Presentación de un caso Giant ovarian cyst and uterine myoma. A case report

    Directory of Open Access Journals (Sweden)

    Carlos Antonio Sánchez Portela

    2012-10-01

    Full Text Available Se presenta un caso de quiste gigante del ovario, en una paciente de 30 años de edad, que fue atendida por el Servicio de Ginecología del Hospital Provincial de Inhambane, en el año 2010, por un aumento de tamaño en el abdomen. Se realizaron los estudios clínicos y ultrasonográficos. Se confirmó a través de una laparotomía exploradora una tumoración quística gigante del ovario con dimensiones extraordinarias y un mioma uterino, lo que es poco frecuente en la actualidad. En el estudio anatomopatológico se comprobó el diagnóstico de cistoadenoma seroso del ovario.A 30-year old patient presenting a giant ovarian cyst was attended at Gynecology service in the Provincial Hospital of Inhambane in 2010, the patient complained of abdominal distension. Clinical and ultrasonographic studies were completed. An exploratory laparotomy confirmed a giant ovarian cyst having odd dimensions and uterine myoma, not frequently found in present times. Pathological studies proved a serous cystadenoma of the ovary.

  2. Quiste gigante de ovario y mioma uterino. Presentación de un caso / Giant ovarian cyst and uterine myoma. A case report

    Scientific Electronic Library Online (English)

    Carlos Antonio, Sánchez Portela; Adonis, García Valladares; Carmen Juana, Sánchez Portela.

    2012-10-01

    Full Text Available Se presenta un caso de quiste gigante del ovario, en una paciente de 30 años de edad, que fue atendida por el Servicio de Ginecología del Hospital Provincial de Inhambane, en el año 2010, por un aumento de tamaño en el abdomen. Se realizaron los estudios clínicos y ultrasonográficos. Se confirmó a t [...] ravés de una laparotomía exploradora una tumoración quística gigante del ovario con dimensiones extraordinarias y un mioma uterino, lo que es poco frecuente en la actualidad. En el estudio anatomopatológico se comprobó el diagnóstico de cistoadenoma seroso del ovario. Abstract in english A 30-year old patient presenting a giant ovarian cyst was attended at Gynecology service in the Provincial Hospital of Inhambane in 2010, the patient complained of abdominal distension. Clinical and ultrasonographic studies were completed. An exploratory laparotomy confirmed a giant ovarian cyst hav [...] ing odd dimensions and uterine myoma, not frequently found in present times. Pathological studies proved a serous cystadenoma of the ovary.

  3. Hallazgo por neuroimaginología de microangiopatía cerebral retiniana con calcificaciones y quistes / Neuroimaging findings in cerebroretinal microangiopathy with calcifications and cysts

    Scientific Electronic Library Online (English)

    Diego Alberto, Herrera; Sergio Alberto, Vargas; Claudia, Montoya.

    2014-06-01

    Full Text Available La microangiopatía cerebral retiniana con calcificaciones y quistes es una enfermedad poco frecuente, caracterizada por alteraciones cerebrales, retinianas y óseas, así como por predisposición al sangrado gastrointestinal. Existen pocos reportes de casos de esta condición, especialmente en adultos, [...] en quienes la incidencia es baja. Los hallazgos por medio de neuroimágenes son característicos, con calcificaciones bilaterales y múltiples formaciones quísticas. El propósito de este artículo fue hacer una revisión bibliográfica e ilustrar dos casos cuyo diagnóstico fue posible con la ayuda de neuroimágenes. Abstract in english Cerebroretinal microangiopathy with calcifications and cysts is a rare condition characterized by brain, retinal and bone anomalies, as well as a predisposition to gastrointestinal bleeding. There are few reported cases of this condition in adults, among whom the incidence is low. Neuroimaging findi [...] ngs are characteristic, with bilateral calcifications, leukoencephalopathy and intracranial cysts. The purpose of this article was to do a literature survey and illustrate two cases diagnosed with the aid of neuroimaging.

  4. Quiste gigante de uraco en el adulto The giant cyst of urachus present in the adult patient

    Directory of Open Access Journals (Sweden)

    Radamés Isaac Adefna Pérez

    2009-06-01

    Full Text Available El quiste de uraco es una anomalía congénita que se incluye entre las lesiones originadas por la persistencia total o parcial de restos de este conducto. Se diagnostica principalmente durante la infancia y su complicación principal es la infección. Presentamos el caso de adulto con una tumoración abdominal gigante quística, diagnosticada como de origen uracal y tratada quirúrgicamente. Se hace una revisión del tema, con énfasis en los aspectos principales del tratamiento de la enfermedad.The urachus cyst is a congenital anomaly included among lesions originated by local or partial resistance of this duct. Is mainly diagnosed during infancy and its main complication is the infection. Authors present the case of an adult patient presenting with a cystic giant abdominal tumor, diagnosed as of urachal origin and treated by surgery. This matter is reviewed emphasizing on main features of disease treatment.

  5. Testicular torsion and weather conditions: analysis of 21,289 cases in Brazil

    Directory of Open Access Journals (Sweden)

    Fernando Korkes

    2012-04-01

    Full Text Available PURPOSE: The hypothesis of association between testicular torsion and hyperactive cremasteric reflex, worsened by cold weather, has not been proved. Thirteen studies in the literature evaluated this issue, with inconclusive results. The aim of the present study was to evaluate the seasonality of testicular torsion in a large subset of patients surgically treated in Brazil, and additionally to estimate the incidence of testicular torsion. MATERIALS AND METHODS: Brazilian Public Health System Database was assessed from 1992-2010 to evaluate hospital admissions associated with treatment of testicular torsion. Average monthly temperature between 1992-2010 was calculated for each region. RESULTS: We identified 21,289 hospital admissions for treatment of testicular torsion. There was a higher number of testicular torsions during colder months (p = 0.002. To estimate the incidence of testicular torsion, we have related our findings to data from the last Brazilian census (2010. In 2010, testicular torsion occurred in 1.4:100,000 men in Brazil. CONCLUSIONS:Testicular torsion occurred at an annual incidence of approximately 1.4:100,000 men in Brazil in 2010. Seasonal variations do occur, with a significant increase of events during winter. Our findings support the theory of etiological role of cold weather to the occurrence of testicular torsion. Strategies to prevent these events can be based on these findings.

  6. Taurine increases testicular function in aged rats by inhibiting oxidative stress and apoptosis.

    Science.gov (United States)

    Yang, Jiancheng; Zong, Xiaomeng; Wu, Gaofeng; Lin, Shumei; Feng, Ying; Hu, Jianmin

    2015-08-01

    In males, the decline of androgen synthesis, spermatogenesis and sexual function are the main phenotypes of aging, which may be attributed to testicular dysfunction. Taurine can act as an antioxidant, a testosterone secretion stimulator, a sperm membrane stabilizer and motility factor, and an anti-apoptotic agent. Recent observational studies suggested that taurine may play an important role in spermatogenesis, but to date whether taurine has anti-aging effects on testes remains unknown. We found that in aged rats testicular SDH and G6PDH activities, marker enzymes of testes, serum testosterone, testicular 3?-HSD and 17?-HSD mRNA expression levels were significantly increased by taurine treatment. Taurine administration also markedly raised the sperm count, viability and motility, decreased the sperm abnormality. Our data suggested that taurine can postpone testicular function deterioration in aged rats. Importantly, we observed obvious elevation of testicular antioxidant enzymes (SOD, GSH, GSH-Px) activities, and remarkable reduction of ROS and MDA by taurine administration, indicating taurine can decrease testicular oxidative stress and lipid peroxidation in aged rats. Finally, we found taurine effectively reduced testicular DNA fragmentation, increased testicular Bcl-2 protein expression, and decreased cytochrome c, Bax, Fas, FasL and caspase-3 expression, suggesting taurine can prohibit aged testicular apoptosis by mitochondrial dependent and independent signal pathway. In summary, our results indicated that taurine can suppress testicular function deterioration by increasing antioxidant ability and inhibiting apoptosis. PMID:25957528

  7. Profundidad tumoral en el carcinoma epidermoide lingual: Repercusiones diagnósticas / Tumor depth in squamous cell carcinoma of the tongue: Diagnostic repercussions

    Scientific Electronic Library Online (English)

    J.D., Sánchez López; M.A., Sicilia Gutiérrez; L.M., Capitán Cañadas; I., Labrot Moleón; S., Martínez-Villalobos Castillo; E., Valencia Laseca.

    2007-02-01

    Full Text Available Objetivo. Determinar el grado de concordancia entre la valoración clínica (cT) e histopatológica (pT) del tamaño del carcinoma epidermoide lingual en relación a la introducción del parámetro de profundidad tumoral (ppT). Material y métodos. 1) Diseño: Estudio retrospectivo de base hospitalaria const [...] ituido por 60 pacientes evaluados desde Enero de 1990 a Julio de 1997 (Seguimiento mínimo de 8 años). 2) Variables: Filiación del paciente, parámetros clínicos y parámetros histopatológicos. 3) Método estadístico: Correlación mediante el Indice Kappa (p Abstract in english Objective. To determine the degree of concordance between clinical (cT) and histopathological (pT) values for tumor size in squamous cell carcinoma when introducing "tumor thickness" as a diagnostic marker. Materials and methods. 1) Design: A retrospective hospital study of 60 patients evaluated bet [...] ween January 1990 and July 1997 was carried out. 2) Variables: Patient dates, clinical and histopathological parameters. 3) Statistics: Correlation assessment by Kappa Index (p

  8. A Rare Case of an Epidermoid Cyst in the Parotid Gland - which was Diagnosed by Fine Needle Aspiration Cytology.

    Science.gov (United States)

    Hegde, Panna N; Prasad H L, Kishan; Kumar Y, Sunil; Sajitha, K; Roy, Pooja Sarda; Raju, Mary; Shetty, Vikram

    2013-03-01

    Cystic lesions are common in the head and neck. The most common are the cutaneous cysts, which are referred to as epidermal cysts. These cysts present as nodular and fluctuant subcutaneous lesions and they are seen most commonly in the acne - prone areas like the head, neck and the back. They arise following a localized inflammation of the hair follicle and occasionally after the implantation of the epithelium, following a trauma or surgery. The presence of benign cystic lesions in the salivary glands is rare.We are presenting a rare case of a 55-year-old male who presented with a soft swelling on the left side of the face. A diagnosis of an epidermoid cyst was given on cytology. A superficial parotidectomy was performed and the histopathology confirmed the above diagnosis. PMID:23634420

  9. Tratamiento quirúrgico de pacientes con quistes de inclusión epidérmica / Surgical treatment of patients with epidermal inclusion cysts

    Scientific Electronic Library Online (English)

    José Manuel, Díaz Fernández; Alejandro Francisco, Agüero Díaz; Manuel, Fonseca Labaut; Carlos Juan, Puig González; Anyi Lucía, Díaz Cardero.

    2014-06-01

    Full Text Available Se realizó un estudio prospectivo, longitudinal y aleatorizado de 29 pacientes con quiste de inclusión epidérmica en la región cervicofacial, no infectados, atendidos en el Servicio de Cirugía Maxilofacial del Hospital Clinicoquirúrgico Docente "Saturnino Lora Torres" de Santiago de Cuba, desde juni [...] o de 2011 hasta noviembre de 2012, tratados quirúrgicamente mediante los métodos de incisión lineal mínima o excisión en W, con vistas a comparar los resultados de ambos procederes. Se obtuvo que el tiempo operatorio promedio fue más corto en el grupo de incisión lineal mínima y que los quistes que medían entre menos de 1 y hasta 2 cm, localizados en las unidades estéticas faciales de mayor exigencia, eran mejor tratados con dicho método, lo cual produjo mejores resultados y un índice recurrencia no significativo en relación con la excisión en W Abstract in english A prospective, longitudinal and randomized study of 29 patients with epidermal inclusion cysts in the cervicofacial region, not infected, assisted in the Maxillofacial Surgery Service of "Saturnino Lora Torres" Teaching Clinical Surgical Hospital in Santiago de Cuba was carried out from June, 2011 t [...] o November, 2012, surgically treated by means of the methods of minimal lineal incision or W excision, with the aim of comparing the results of both procedures. It was obtained that the average surgical time was shorter in the group of minimal lineal incision and that the cysts fluctuating from less than 1 cm and up to 2 cm, located in the facial aesthetic units of greater demand, were better treated with this method, what produced better results and a non significant recurrence value in relation to the W excision

  10. Identificación de células proliferativas en quistes de Taenia solium / Identification of proliferating cells in Taenia solium cysts

    Scientific Electronic Library Online (English)

    Miguel Ángel, Orrego-Solano; Carla, Cangalaya; Theodore E., Nash; Cristina, Guerra-Giraldez.

    2014-12-01

    Full Text Available Los neoblastos son células totipotentes, únicas responsables de la proliferación y maduración de tejidos en platelmintos de vida libre. Células similares se han aislado en platelmintos parásitos como Echinococcus. Taenia solium causa la teniasis humana (intestinal) y la cisticercosis en humanos y ce [...] rdos. La infección del cerebro con larvas (quistes) de T. solium resulta en neurocisticercosis, hiperendémica en el Perú; su tratamiento se asocia a síntomas neurológicos graves. La capacidad proliferativa y el desarrollo de los estadios de T. solium aún no se describen, y no se ha caracterizado los neoblastos de este parásito. Se buscó células proliferativas en quistes de T. solium colectados de un cerdo infectado, que fueron identificadas al replicarse e incorporar el nucleótido bromodesoxiuridina, detectado con un anticuerpo monoclonal. Una línea celular estable de neoblastos sería útil para estudios sistemáticos in vitro sobre eficacia de drogas y sobre la biología de T. solium. Abstract in english Neoblasts are totipotent cells, solely responsible for the proliferation and maturation of tissues in free-living flatworms. Similar cells have been isolated from parasitic flatworms such as Echinococcus. Taenia solium causes human taeniasis (intestinal) and cysticercosis in humans and pigs. Brain i [...] nfection with larvae (cysts) of T. solium results in neurocysticercosis which is hyperendemic in Peru, and its treatment is associated with serious neurological symptoms. The proliferative capacity and development stages of T. solium have not been described and the neoblasts of this parasite have not been characterized We looked for cell proliferation in T. solium cysts collected from an infected pig, which were identified when replicating and incorporating bromodeoxyuridine nucleotide detected with a monoclonal antibody. A stable cell line of neoblasts would be useful for systematic in vitro studies on drug efficacy and the biology of T. solium.

  11. Identificación de células proliferativas en quistes de Taenia solium / Identification of proliferating cells in Taenia solium cysts

    Scientific Electronic Library Online (English)

    Miguel Ángel, Orrego-Solano; Carla, Cangalaya; Theodore E, Nash; Cristina, Guerra-Giraldez.

    2014-10-01

    Full Text Available Los neoblastos son células totipotentes, únicas responsables de la proliferación y maduración de tejidos en platelmintos de vida libre. Células similares se han aislado en platelmintos parásitos como Echinococcus. Taenia solium causa la teniasis humana (intestinal) y la cisticercosis en humanos y ce [...] rdos. La infección del cerebro con larvas (quistes) de T. solium resulta en neurocisticercosis, hiperendémica en el Perú; su tratamiento se asocia a síntomas neurológicos graves. La capacidad proliferativa y el desarrollo de los estadios de T. solium aún no se describen, y no se ha caracterizado los neoblastos de este parásito. Se buscó células proliferativas en quistes de T. solium colectados de un cerdo infectado, que fueron identificadas al replicarse e incorporar el nucleótido bromodesoxiuridina, detectado con un anticuerpo monoclonal. Una línea celular estable de neoblastos sería útil para estudios sistemáticos in vitro sobre eficacia de drogas y sobre la biología de T. solium. Abstract in english Neoblasts are totipotent cells, solely responsible for the proliferation and maturation of tissues in free-living flatworms. Similar cells have been isolated from parasitic flatworms such as Echinococcus. Taenia solium causes human taeniasis (intestinal) and cysticercosis in humans and pigs. Brain i [...] nfection with larvae (cysts) of T. solium results in neurocysticercosis which is hyperendemic in Peru, and its treatment is associated with serious neurological symptoms. The proliferative capacity and development stages of T. solium have not been described and the neoblasts of this parasite have not been characterized We looked for cell proliferation in T. solium cysts collected from an infected pig, which were identified when replicating and incorporating bromodeoxyuridine nucleotide detected with a monoclonal antibody. A stable cell line of neoblasts would be useful for systematic in vitro studies on drug efficacy and the biology of T. solium.

  12. Desenvolvimento testicular, espermatogênese e concentrações hormonais em touros Angus Testicular development, spermatogenesis and hormonal concentrations in Angus bulls

    Directory of Open Access Journals (Sweden)

    Gyselle Viana Aguiar

    2006-08-01

    Full Text Available Este estudo foi realizado com a finalidade de avaliar a evolução das secreções hormonais e do epitélio seminífero em touros da raça Angus de 10 a 38 semanas de idade. Foram castrados 1 a 5 animais em intervalos de quatro semanas (total de 25 touros para coleta de amostras do parênquima testicular e do plasma sanguíneo. As variáveis relacionadas ao crescimento testicular, aos aspectos quantitativos da espermatogênese e aos níveis hormonais foram transformadas em logaritmo e avaliadas por meio de análise de variância. O diâmetro dos testículos e túbulos seminíferos e o peso testicular apresentaram variações mais acentuadas após 26 semanas de idade. A porcentagem do parênquima testicular ocupado pelos túbulos seminíferos aumentou de 49,3 para 75,2% durante o experimento. A maioria dos túbulos (>90% apresentou-se com células de Sertoli somente entre 10 e 14 semanas, mas na 18ª (13,8±1,7% e 22ª semanas (19±1%, o número de túbulos com gonócitos e espermatogônias aumentou em relação às semanas iniciais. Espermatogônias intermediárias e B predominaram na 26ª semana (24,5±8,2% e a porcentagem de túbulos com espermatócitos foi mais elevada na 30ª semana (42,3±9,9%. Espermátides arredondadas foram detectadas partir da 26ª semana e, na 38ª semana, 62,3±1,5% dos túbulos seminíferos continham espermátides alongadas ou maduras. As variações mais acentuadas no crescimento testicular e, principalmente, no peso testicular após as 26 semanas coincidiram com o estabelecimento da meiose, com as alterações morfológicas do núcleo e nucléolo das células de Sertoli (indicativos do processo de diferenciação das mesmas, com os níveis reduzidos de androstenediona e os incrementos significativos de testosterona e estradiol 17beta. As associações entre o crescimento testicular e os níveis de FSH e LH na circulação periférica foram menos evidentes.This study aimed to evaluate changes in hormone secretion and in seminiferous epithelium of Angus bulls between 10 and 38 weeks of age. Samples of testicular parenchyma and blood were collected from 25 animals castrated in 4 week intervals. Traits associated to testicular development and quantitative aspects of spermatogenesis and hormonal concentrations were transformed by logarithm before analyses of variance. Changes in testis and seminiferous tubule diameter and testis weight were more pronounced after 26 weeks of age. The percentage of testicular parenchyma occupied by seminiferous tubules increased from 49.3 to 75.2% from 10 to 38 weeks. Most tubules (>90% had only Sertoli cells at 10 and 14 weeks, but the number of tubules with gonocytes and A spermatogonia increased at 18 (13.8±1.7% and 22 weeks (19±1%. Tubules with B and intermediate spermatogonia became predominant at 26 weeks (24.5±8.2% and those with spermatocytes as the most advanced germ cell type were more evident at 30 weeks (42.3±9.9%. Round spermatids were detected at 26 weeks and at 38 weeks of age, 62.3±1.5% of all tubules had either elongate or mature spermatids. Variations in testis growth (specially testis weight after 26 weeks were coincident with the establishment of meiosis in the seminiferous tubules, morphological alterations in nucleus and nucleolus of the Sertoli cells (indicators of Sertoli cell differentiation, lower levels of androstenedione and significant increases in testosterone and estradiol 17beta. Associations between testis development and concentrations of FSH and LH were less evident.

  13. Desenvolvimento testicular, espermatogênese e concentrações hormonais em touros Angus / Testicular development, spermatogenesis and hormonal concentrations in Angus bulls

    Scientific Electronic Library Online (English)

    Gyselle Viana, Aguiar; Airton Alencar, Araújo; Arlindo de Alencar Araripe, Moura.

    2006-08-01

    Full Text Available Este estudo foi realizado com a finalidade de avaliar a evolução das secreções hormonais e do epitélio seminífero em touros da raça Angus de 10 a 38 semanas de idade. Foram castrados 1 a 5 animais em intervalos de quatro semanas (total de 25 touros) para coleta de amostras do parênquima testicular e [...] do plasma sanguíneo. As variáveis relacionadas ao crescimento testicular, aos aspectos quantitativos da espermatogênese e aos níveis hormonais foram transformadas em logaritmo e avaliadas por meio de análise de variância. O diâmetro dos testículos e túbulos seminíferos e o peso testicular apresentaram variações mais acentuadas após 26 semanas de idade. A porcentagem do parênquima testicular ocupado pelos túbulos seminíferos aumentou de 49,3 para 75,2% durante o experimento. A maioria dos túbulos (>90%) apresentou-se com células de Sertoli somente entre 10 e 14 semanas, mas na 18ª (13,8±1,7%) e 22ª semanas (19±1%), o número de túbulos com gonócitos e espermatogônias aumentou em relação às semanas iniciais. Espermatogônias intermediárias e B predominaram na 26ª semana (24,5±8,2%) e a porcentagem de túbulos com espermatócitos foi mais elevada na 30ª semana (42,3±9,9%). Espermátides arredondadas foram detectadas partir da 26ª semana e, na 38ª semana, 62,3±1,5% dos túbulos seminíferos continham espermátides alongadas ou maduras. As variações mais acentuadas no crescimento testicular e, principalmente, no peso testicular após as 26 semanas coincidiram com o estabelecimento da meiose, com as alterações morfológicas do núcleo e nucléolo das células de Sertoli (indicativos do processo de diferenciação das mesmas), com os níveis reduzidos de androstenediona e os incrementos significativos de testosterona e estradiol 17beta. As associações entre o crescimento testicular e os níveis de FSH e LH na circulação periférica foram menos evidentes. Abstract in english This study aimed to evaluate changes in hormone secretion and in seminiferous epithelium of Angus bulls between 10 and 38 weeks of age. Samples of testicular parenchyma and blood were collected from 25 animals castrated in 4 week intervals. Traits associated to testicular development and quantitativ [...] e aspects of spermatogenesis and hormonal concentrations were transformed by logarithm before analyses of variance. Changes in testis and seminiferous tubule diameter and testis weight were more pronounced after 26 weeks of age. The percentage of testicular parenchyma occupied by seminiferous tubules increased from 49.3 to 75.2% from 10 to 38 weeks. Most tubules (>90%) had only Sertoli cells at 10 and 14 weeks, but the number of tubules with gonocytes and A spermatogonia increased at 18 (13.8±1.7%) and 22 weeks (19±1%). Tubules with B and intermediate spermatogonia became predominant at 26 weeks (24.5±8.2%) and those with spermatocytes as the most advanced germ cell type were more evident at 30 weeks (42.3±9.9%). Round spermatids were detected at 26 weeks and at 38 weeks of age, 62.3±1.5% of all tubules had either elongate or mature spermatids. Variations in testis growth (specially testis weight) after 26 weeks were coincident with the establishment of meiosis in the seminiferous tubules, morphological alterations in nucleus and nucleolus of the Sertoli cells (indicators of Sertoli cell differentiation), lower levels of androstenedione and significant increases in testosterone and estradiol 17beta. Associations between testis development and concentrations of FSH and LH were less evident.

  14. Effect of 5-alpha-reductase inhibitor, 4-MAPC, on testicular descent in male rat.

    Science.gov (United States)

    Ngyuen, M M; Lemmi, C A; Rajfer, J

    1991-05-01

    Testicular descent has been reported to be a dihydrotestosterone (DHT) dependent event. To further elucidate the role of DHT in the process of testicular descent, a group of rats were treated with the 5-alpha reductase inhibitor, 4-MAPC, from birth to day 28 of age and the incidence of testicular descent as well as ventral prostate weight was noted at day 29 of age. It was determined that in the doses used, 4-MAPC failed to prevent testicular descent. Because 4-MAPC inhibited ventral prostate weight by only 53% (as compared to a 75% inhibition by castration), the failure of the 4-MAPC to prevent testicular descent could be due to its inability to completely inhibit tissue 5-alpha reductase activity. The results of this study do not mitigate against the role of other nonhormonal factors working in tandem with DHT in the induction of testicular descent in this animal model. PMID:2016800

  15. Tratamiento quirúrgico conservador del quiste dentígero en pacientes pediátricos atendidos en el postgrado de cirugía bucal facultad de odontología de la UCV: Seguimiento a largo plazo

    Scientific Electronic Library Online (English)

    Sol C, Del Valle; José A, Cedeño; Raúl, García-Arocha; César, Guerrero.

    2007-09-01

    Full Text Available RESUMEN De acuerdo a numerosos autores el tratamiento para el quiste dentígero ha sido la eliminación total del quiste incluyendo el diente involucrado aunque si la lesión se presenta en pacientes jóvenes que están en período de erupción dentaria y las características clínicas y radiográficas sugier [...] en la presencia de un quiste dentígero, existe una alternativa de tratamiento la cual es la de mantener el diente permanente no erupcionado y enuclear completamente la lesión, siempre que se obtenga el diagnóstico definitivo histopatológico confirmatorio de quiste dentígero. Se realizó un estudio clínico en 12 pacientes de 7 a 16 años de edad con un promedio de 9,4 años, quienes fueron tratados en el Postgrado de Cirugía Bucal de la Facultad de Odontología de la Universidad Central de Venezuela (UCV). Todos los pacientes tenían las características clínicas y radiográficas similares a las del quiste dentígero, se encontraron 5 mujeres y 7 hombres, los cuales fueron sometidos a biopsia excisional, donde se les eliminó la lesión por completo, dejándoles el diente permanente no erupcionado. Las lesiones eran en la mandíbula y las imágenes radiolúcidas eran bien delimitadas al cuello dentario y menores a 2,5 cms. de diámetro. Los pacientes con quiste dentígero asociado a un tercer molar fueron excluídos del estudio. El estudio histopatológico fue confirmatorio de quiste dentígero para cada paciente y a cada uno se les realizó un seguimiento clínico y radiográfico periódico desde 2 meses hasta 7 años, con un intervalo aproximado de cada 6 meses. (1999-2006). No se encontraron imágenes radiolúcidas en ninguna de las radiografías post-quirúrgicas. Todos mostraron nueva formación ósea alrededor del diente involucrado y erupción completa de la dentición permanente. Tres(3) pacientes fueron seguidos por 7 años, cuatro(4) por 5 años, dos(2) por 3 años con 9 meses y tres(3) por 2 años y 6 meses. A dos(2) de los pacientes se les realizó tratamiento ortodóncico para corregir su maloclusión. Preservar el diente involucrado en un Quiste Dentígero al enuclear totalmente la lesión es una alternativa de procedimiento quirúrgico  con resultados clínicos y radiográficos predecibles y estables. Este tratamiento puede ser usado como un manejo quirúrgico conservador que permite la erupción normal de la dentición permanente. Éste estudio enfatiza la importancia del manejo multidisciplinario en equipo (Cirujano Bucal, Patólogo Bucal, Ortodoncista y Odontopediatra) y el control radiográfico postquirúrgico contínuo de los pacientes para asegurarnos de que no ha habido recidiva o la aparición de alguna nueva patología asociada Abstract in english ABSTRACT According to most authors the common treatment for the dentigerous cyst has been total elimination of the cyst including the tooth involved; however if the lesion is present in young patients during the eruption period, and the radiographic and clinical features are suggesting of dentigerou [...] s cyst, an alternative treatment is the maintenance of the permanent tooth and enucleation of the lesion alone, stating that ameloblastomatous changes or other odontogenic lesions have been ruled out after histopathological analysis, and a diagnosis of dentigerous cyst is confirmed. This study was conducted on 12 patients with an age range of 6 to 16 years with a mean age of 9.4 years that were treated at the Oral Surgery Postgraduate Department, Dental School, Central University of Venezuela. There were 5 females and 7 males. All lesions were mandibular and all of them were unilocular and well-defined radiolucencies measuring less than 2,5 cms in greatest diameter. All cases involved the coronal portion with cervical attachment of an unerupted permanent tooth. Third molars were excluded. Patients underwent surgery (excisional biopsy) of the cyst with preservation of the involved tooth. Histologic diagnosis of dentigerous cyst was confirmed in each case. Clinical and radiographic follow-up was performed at 6 months

  16. Incidental Discovery of Testicular Microlithiasis: What Is the Importance of Ultrasound Surveillance? Two Case Reports

    OpenAIRE

    Barchetti, F.; Marco, V; Barchetti, G.; Pasqualitto, E.; A. Sartori; Glorioso, M.; Gigli, S.; V. Megna; Montechiarello, S.; Boncore, V.; STAGNITTI, A.

    2013-01-01

    Many studies have demonstrated an association between diffuse bilateral testicular microlithiasis (TM) and gonadal and extragonadal germ cell tumors. Nevertheless, it is still uncertain whether ultrasound surveillance is really necessary in patients with TM in the absence of other risk factors such as previous testicular cancer, a history of cryptorchidism or testicular atrophy. We report the cases of a 33- and a 39-year-old man presenting with a retroperitoneal extragonadal tumor. The first ...

  17. Testicular Metastasis in a Case of Squamous Cell Carcinoma of the Lung

    OpenAIRE

    Buck, Dennis Andrew; Byrd, Robert H.; Holmes, Cynthia L.; Pollock, Theodore

    2015-01-01

    Testicular metastases are a rare finding. Typically, a testicular metastasis will present as a complication of progressive disease or as a primary sign of malignancy. Excluding lymphoma and leukemia, prostate cancer is the most common primary site that metastasizes to the testes. Testicular metastases resulting from squamous cell carcinoma of the lung have rarely been reported in previous literature. Here, we report a case of stage IV squamous cell carcinoma of the lung with metastases to the...

  18. Testicular Involvement in Wegener Granulomatosis: Case Report and Review of the literature

    Directory of Open Access Journals (Sweden)

    Mehmet Nuri TURAN

    2012-05-01

    Full Text Available Wegener granulomatosis (WG is a type of necrotising vasculitis that affects mainly the respiratory tract, paranasal sinuses and the kidneys. Urogenital involvement is rare; mainly affecting the prostate gland. Testicular involvement in WG is exceptional. We report a 50-year-old male patient with hematuria, proteinuria and testicular pain and renal failure diagnosed as WG by testicular and kidney biopsy. We also provide a review of the literature.

  19. Birth order, sibship size, and risk for germ-cell testicular cancer

    OpenAIRE

    RICHIARDI, LORENZO

    2004-01-01

    BACKGROUND: Several studies have reported an inverse association between birth order and testicular cancer risk, but estimates vary greatly and the biologic mechanism underlying the association is not established. METHODS: We have evaluated the effect of birth order, sibship size, and the combined effect of these 2 variables in relation to risk for testicular cancer in a large, nested case-control study. Specifically, we compared 3051 patients with germ-cell testicular cancer (diagnosed betwe...

  20. Effects of testicular microlithiasis on Doppler parameters: report of three cases

    OpenAIRE

    Alkan Alpay; Baysal Tamer; Sigirci Ahmet; Kutlu Ramazan; Sarac Kaya

    2002-01-01

    Abstract Background Testicular microlithiasis is a rare, usually asymptomatic, non-progressive disease of the testes associated with various genetic anomalies, infertility and testicular tumors. According to our literature search, there is no specific data about Doppler findings in this disease. Case presentation Doppler findings of three cases of testicular microlithiasis during last two years in our institution are presented. Conclusions Although our hypothesis was to find increased Doppler...

  1. Advanced and recurrent testicular rhabdomyosarcoma in a young adult: A rare case report

    Directory of Open Access Journals (Sweden)

    L Purnima Devi

    2015-01-01

    Full Text Available Rhabdomyosarcoma (RMS is one of the most frequent soft tissue sarcomas. Pure testicular RMS is a very rare tumor and a few cases have been reported in the literature. We report a 16-year-old male patient with a painless right testicular swelling who underwent high inguinal orchiectomy and diagnosed as testicular embryonal RMS. The patient had a rare recurrence at the scrotal site with inguinal and retroperitoneal metastasis.

  2. Duplicación del tubo digestivo manifestada como quiste lingual: Caso clínico y revisión de la literatura / Enteric duplication presented as lingual cyst: Case report and literature review

    Scientific Electronic Library Online (English)

    José Guillermo, Milán-Montenegro; Yolanda, Jaramillo-Rodríguez; Jesús, Nares-Cisneros; Jaime, Guerrero-Sepúlveda.

    2014-06-01

    Full Text Available Introducción: Los quistes de duplicación intestinal son anormalidades poco frecuentes que se presentan principalmente en el período perinatal, y pueden causar problemas respiratorios y para la alimentación. Los quistes sublinguales de duplicación intestinal pueden presentar solo epitelio del aparato [...] digestivo, del respiratorio o de ambos. En los dos últimos casos se denominan coristomas. Caso clínico: Se describe un caso de un paciente de 10 meses de edad que presentó una masa quística sublingual desde el nacimiento. Se realizó la resección total con abordaje transoral y la reconstrucción de la lengua en planos. La pieza quirúrgica resultó una estructura quística de contenido mucoide, de 23 × 17 × 11 mm y color marrón. El revestimiento del quiste estaba formado por mucosa gástrica, con epitelio foveolar y glándulas formadas por células parietales y principales. Conclusiones: El quiste de duplicación intestinal es una entidad extremadamente rara. El abordaje quirúrgico es eficaz y curativo con mínima morbilidad y mortalidad, sin recurrencia en su seguimiento. Abstract in english Background: Intestinal duplication cysts are rare abnormalities that occur primarily during the perinatal period and may cause problems for feeding and/or breathing. Sublingual intestinal duplication cysts can present either gastrointestinal epithelium or respiratory or both; the latter two cases ar [...] e called choristomas. Case report: We describe a 10-month-old infant who presented a sublingual cystic mass at birth. Total successful transoral resection and reconstruction of the tongue was performed in planes. The surgical specimen was a brown cystic structure of mucoid content with dimensions of 23 × 17 × 11 mm. The cyst lining consists of gastric mucosa with foveolar epithelium and glands composed of parietal and chief cells. Conclusions: The intestinal duplication cyst is an extremely rare entity. The surgical approach is effective and curative with minimal morbidity and mortality and without recurrence in follow-up.

  3. CANCER TESTICULAR: ESTUDIO DE EXTENSION CON TC DE CUERPO ENTERO

    Directory of Open Access Journals (Sweden)

    Jaime Schwaner C

    2005-01-01

    Full Text Available Introducción. La evaluación con tomografía computada (TC de tórax, abdomen y pelvis de pacientes con cáncer testicular es importante para determinar la extensión de su enfermedad y los controles post-tratamiento. Quienes presentan metástasis son candidatos a quimioterapia lo que permite una supervivencia mayor al 80% en el largo plazo. Objetivos: Estimar la frecuencia de invasión regional y a distancia usando TC de cuerpo entero en los diferentes tipos histológicos de cáncer testicular y correlacionar con las pautas de pronóstico del Consenso Europeo para el diagnóstico y tratamiento de este tipo de cáncer. Material y método: Nuestro estudio incluyó 85 pacientes con cáncer testicular diagnosticados por clínica y estudio ecotomográfico en el Hospital Regional de Concepción entre los años 2002 a 2005. A todos ellos se les realizó TC tórax-abdomen-pelvis para estadificación. Los estudios fueron realizados con escáner helicoidal usando en forma rutinaria contraste oral y endovenoso no iónico en dosis estándar de 150 ml. Las imágenes axiales y reconstruidas fueron analizadas por radiólogos del servicio de imagenología. Se consigno la presencia, y ubicación de linfonódulos metastásicos y metástasis. El estudio histológico del tumor testicular se relacionó con su estadificación según la TC de cuerpo entero, siendo luego agrupados en grupos pronósticos para estimar probabilidad de sobrevida. Resultados: En nuestra casuística, los tumores testiculares afectan a varones con un promedio de edad de 31 años y en un rango de 19 a 57 años. Según TNM (AJCC staging system 1997: en etapa I estaban 43 pacientes (50,6%, en etapa II 20 (23,5% y en etapa III 22 (25,9%. En 43 pacientes el tipo histológico fue seminoma clásico puro y en 42 no-seminoma. De los 42 pacientes con tumores no seminomas: cinco presentaron carcinoma em-brionario puro y 20 mixto, coriocarcinoma mixto se observo en seis, teratoma maduro en siete y en un paciente teratoma inmaduro. Sólo tres casos presentaron teratocarcinomas. Conclusión: La proporción de seminomas y no seminomas se correlaciona con la literatura nacional e internacional, excepto con un estudio del grupo español. Nuestros grupos pronósticos difieren con los del Consenso Europeo para el diagnóstico y tratamiento del tumor testicular. Pensamos que la Rx de tórax se podría obviar en la evaluación inicial y usar solamente TC de tórax, abdomen y pelvis en los centros que cuenten con tecnología helicoidal, ya que de esta forma evitamos una reevaluación en los casos de radiografía sospechosa o con signos de diseminación secundaria, usando una sola inyección de contraste, apnea y tiempo de examen.Today testicular cancer has good treatment and long-term survival. Thorax, abdomen and pelvis computerized tomography especially helical technique is the most important tool to evaluate dissemination. We analyzed retrospectively 85 patients studied in the Hospital Regional de Concepción between 2002-2005 with testicular tumors whom had complete laboratory and TC helical evaluation and correlated local invasion detected in surgery with CT staging for estimate prognostic survival in agree with European consensus on diagnosis and treatment of germ cell cancer. The mean age at the time of diagnosis was 31 years (Range 19-57. Forty three were seminoma and 42 non seminomatous tumors. Staging demonstrated 43 stage I, 20 stage II and 22 stage III. Our prognostic groups were different to other series with 71% of patient's good prognostic, 24% intermediate and only 5% bad prognostic (non seminomatous tumors. We think that the new technology helical can obviate chest x-ray in the initial evaluation of these patients

  4. Inhibitory effect of chondroitin sulfate oligosaccharides on bovine testicular hyaluronidase.

    Science.gov (United States)

    Kakizaki, Ikuko; Koizumi, Hideyo; Chen, Fengchao; Endo, Masahiko

    2015-05-01

    Hyaluronan and chondroitin sulfates are prominent components of the extracellular matrices of animal tissues; however, their functions in relation to their oligosaccharide structures have not yet been fully elucidated. The oligosaccharides of hyaluronan and chondroitin sulfate were prepared and used to investigate their effects on the hydrolysis and transglycosylation reactions of bovine testicular hyaluronidase when hyaluronan was used as a substrate. Hydrolysis and transglycosylation activities were assessed in independent reaction systems by analyzing the products by HPLC. The hydrolysis and transglycosylation reactions of bovine testicular hyaluronidase were dose-dependently inhibited by chondroitin sulfate oligosaccharides, but not by hyaluronan or chondroitin oligosaccharides. A kinetic analysis of the hydrolysis reaction using hyaluronan octasaccharide revealed that the inhibition mode by chondroitin sulfate oligosaccharides was competitive. PMID:25659711

  5. Frequent complaints of testicular lumps by young prisoners.

    Science.gov (United States)

    Mohanty, Kailash C

    2008-05-01

    The definition of the age of young offenders was changed by an Act of Parliament (The Crime and Disorder Act 1998), which was implemented by the Home Office on 1 April 2000. This Act brought down the upper-age limit of young offenders from 20 to 17. Our objective was to investigate the sexually transmitted infections (STIs) among this redefined group of young offenders. Among various types of STIs, we observed that a significant number of young prisoners had complaints of testicular lumps (35%), which were not reported in the past. We tried to find out the reason for this common complaint and believe that this was due to extra vigilance, and testicular self-examination in conjunction with sex and relationship programmes which ran alongside other programmes developed as a joint venture by Prisoner Learning and Skills Unit, Prison Health Policy Unit and Sex Education Forum. PMID:18482964

  6. Gynecomastia caused by testicular irradiation. A case report

    Energy Technology Data Exchange (ETDEWEB)

    Mori, Hiroki; Umeda, Tadashi; Katayama, Ichiro; Nishioka, Kiyoshi [Tokyo Medical and Dental Univ. (Japan). School of Medicine

    1996-09-01

    Gynecomastia in a 20-years-old male is reported. At the age of 2, the patients had contracted acute lymphocytic leukemia (ALL), at which time irradiation for the testicular ALL invasion was performed. This irradiation induced atrophy of the testis. Obesity was first noted when he was 12 years old, after which enlargement of the bilateral breasts occurred at 14 years of age. When he turned 19, supplementary testosterone therapy was initiated to counter the gynecomastia, but it proved ineffective. Thus, a total mastectomy was performed with free nipple grafting. Pathologically, inspected mammary tissue specimens revealed mammary ducts in a fibrous stroma that had encompassed lobules of adipose tissue. The findings in this case suggest that the testicular irradiation had induced primary hypogonadism and that this had resulted in gynecomastia and obesity. (author)

  7. Gynecomastia caused by testicular irradiation. A case report

    International Nuclear Information System (INIS)

    Gynecomastia in a 20-years-old male is reported. At the age of 2, the patients had contracted acute lymphocytic leukemia (ALL), at which time irradiation for the testicular ALL invasion was performed. This irradiation induced atrophy of the testis. Obesity was first noted when he was 12 years old, after which enlargement of the bilateral breasts occurred at 14 years of age. When he turned 19, supplementary testosterone therapy was initiated to counter the gynecomastia, but it proved ineffective. Thus, a total mastectomy was performed with free nipple grafting. Pathologically, inspected mammary tissue specimens revealed mammary ducts in a fibrous stroma that had encompassed lobules of adipose tissue. The findings in this case suggest that the testicular irradiation had induced primary hypogonadism and that this had resulted in gynecomastia and obesity. (author)

  8. Phthalate-induced testicular dysgenesis syndrome: Leydig cell influence.

    Science.gov (United States)

    Hu, Guo-Xin; Lian, Qing-Quan; Ge, Ren-Shan; Hardy, Dianne O; Li, Xiao-Kun

    2009-04-01

    Phthalates, the most abundantly produced plasticizers, leach out from polyvinyl chloride plastics and disrupt androgen action. Male rats that are exposed to phthalates in utero develop symptoms characteristic of the human condition referred to as testicular dysgenesis syndrome (TDS). Environmental influences have been suspected to contribute to the increasing incidence of TDS in humans (i.e. cryptorchidism and hypospadias in newborn boys and testicular cancer and reduced sperm quality in adult males). In this review, we discuss the recent findings that prenatal exposure to phthalates affects Leydig cell function in the postnatal testis. This review also focuses on the recent progress in our understanding of how Leydig cell factors contribute to phthalate-mediated TDS. PMID:19278865

  9. Testicular germ cell tumors: Molecular genetic and clinicomorphological aspects

    Directory of Open Access Journals (Sweden)

    M. V. Nemtsova

    2015-03-01

    Full Text Available Testicular tumors are the most common form of solid cancer in young men. According to the 2004 WHO classification, testicular germ cell tumors (TGCT may present with different histological types. Embryonic cells of varying grade may be a source of TGCT and the occurrence of this type of tumors is directly related to the formation of a pool of male sex cells and gametogenesis. The paper gives information on mo- lecular stages for the process of formation of male sex cells in health, as well as ways of their impairments leading to TGCT. An investigation of the profiles of gene expression and the spectrum of molecular damages revealed genes responsible for a predisposition to the sporadic and hereditary forms of TGCT. The paper presents the current molecular genetic and clinicomorphological characteristics of TGCT. 

  10. Tratamiento quirúrgico conservador en un caso de quiste de iris postraumático / Conservative surgical management of a post-traumatic iris cyst

    Scientific Electronic Library Online (English)

    M., Moreno-López; C., Arruabarrena; A., Regueras; S., Noval.

    2007-07-01

    Full Text Available Caso clínico: Varón de 32 años aquejado de pérdida visual en ojo derecho (OD) secundario a un quiste que ocupa la mitad de la cámara anterior, diagnosticado clínicamente de quiste secundario epitelial de iris. Tres años antes había sufrido un traumatismo penetrante. Se realiza aspiración con aguja, [...] viscodisección y fotocoagulación ab externo, logrando una rápida recuperación visual sin secuelas funcionales ni anatómicas. A los seis meses la agudeza visual permanece estable sin recidiva de la lesión. Discusión: El manejo quirúrgico conservador mediante aspiración y fotocoagulación en este caso fue eficaz y seguro en el tratamiento del quiste epitelial adquirido de iris. Abstract in english Case report: A 32-year-old man with recent visual loss in his right eye, was found to have an iris cyst involving about 50% of the anterior chamber. He had been treated three years previously for a penetrating injury to that eye. The cyst was treated by aspiration, viscodissection and ab-externo pho [...] tocoagulation, with this achieving a rapid recovery of vision and good anatomic results. At the six month follow-up visit the visual acuity remains stable with no signs of recurrence of the cyst. Discussion: Conservative surgical treatment consisting of aspiration, viscodissection and photocoagulation appears to be an effective strategy to manage secondary anterior chamber cysts, achieving good anatomic and functional results.

  11. Quiste de Gorlin asociado a Odontoma: reporte de un caso con su tratamiento quirúrgico / Gorlin cyst associated with odontoma: Case report with surgical treatment

    Scientific Electronic Library Online (English)

    P., Villarroel Castro; R., Fariña Sirandoni; I., Espinoza Santander.

    2005-12-01

    Full Text Available El quiste de Gorlin es un quiste odontogénico que puede presentarse en dos variedades, una quística rodeada por epitelio y de carácter benigno, y una neoplásica localmente agresiva. Se presenta elcaso de una mujer de 18 años con aumento de volumen facial indoloro en región infraorbitaria izquierda. [...] Se realiza la exéresis total de la lesión. Con el estudio histopatológico se obtiene el diagnóstico definitivo de quiste de Gorlin asociado a odontoma. Luego de controles por 3 años, se observa el restablecimiento de la simetría facial, una adecuada regeneración ósea y de los tejidos adyacentes, sin signos de recidiva. Abstract in english Gorlin cyst is an odontogenic cyst that may appear as two types, one cystic and surrounded by epithelium of a benign nature, and the other a locally aggressive neoplasm. The case is presented of an 18-year-old female that had experienced an increase in facial volume in the left infraorbital area tha [...] t was painless. Total exeresis of the lesion was carried out. The histopathologic study provided the definitive diagnosis of Gorlin cyst associated with odontoma. After a follow-up of three years, facial symmetry was reestablished, there was adequate regeneration of bone and of the adjacent tissue, and there were no signs of relapse.

  12. Quiste de Gorlin asociado a Odontoma: reporte de un caso con su tratamiento quirúrgico Gorlin cyst associated with odontoma: Case report with surgical treatment

    Directory of Open Access Journals (Sweden)

    P. Villarroel Castro

    2005-12-01

    Full Text Available El quiste de Gorlin es un quiste odontogénico que puede presentarse en dos variedades, una quística rodeada por epitelio y de carácter benigno, y una neoplásica localmente agresiva. Se presenta elcaso de una mujer de 18 años con aumento de volumen facial indoloro en región infraorbitaria izquierda. Se realiza la exéresis total de la lesión. Con el estudio histopatológico se obtiene el diagnóstico definitivo de quiste de Gorlin asociado a odontoma. Luego de controles por 3 años, se observa el restablecimiento de la simetría facial, una adecuada regeneración ósea y de los tejidos adyacentes, sin signos de recidiva.Gorlin cyst is an odontogenic cyst that may appear as two types, one cystic and surrounded by epithelium of a benign nature, and the other a locally aggressive neoplasm. The case is presented of an 18-year-old female that had experienced an increase in facial volume in the left infraorbital area that was painless. Total exeresis of the lesion was carried out. The histopathologic study provided the definitive diagnosis of Gorlin cyst associated with odontoma. After a follow-up of three years, facial symmetry was reestablished, there was adequate regeneration of bone and of the adjacent tissue, and there were no signs of relapse.

  13. An unusual case of intra-abdominal testicular torsion: Role of laparoscopy

    Directory of Open Access Journals (Sweden)

    Alfonso Papparella

    2013-01-01

    Full Text Available The authors report a case of intra-abdominal testicular torsion, where laparoscopy has been useful for diagnosis and surgical management. A boy was presented with a left impalpable testis. Laparoscopy revealed a twisted spermatic cord at the inlet pelvis, which ended in a testicular remnant located in the sub-umbilical area. After orchiectomy, the pathologist confirmed testicular atrophy. Diagnosis of intra-abdominal testicular torsion should be considered in patients with impalpable testis and abdominal pain, but could not be excluded in those with no symptoms.

  14. Effects of testicular microlithiasis on Doppler parameters: report of three cases

    Directory of Open Access Journals (Sweden)

    Alkan Alpay

    2002-02-01

    Full Text Available Abstract Background Testicular microlithiasis is a rare, usually asymptomatic, non-progressive disease of the testes associated with various genetic anomalies, infertility and testicular tumors. According to our literature search, there is no specific data about Doppler findings in this disease. Case presentation Doppler findings of three cases of testicular microlithiasis during last two years in our institution are presented. Conclusions Although our hypothesis was to find increased Doppler parameters due to intratesticular arterial compression, our findings suggest that there are no Doppler findings specific to testicular microlithiasis.

  15. Bone disease in testicular and extragonadal germ cell tumours.

    OpenAIRE

    Hitchins, R. N.; Philip, P A; Wignall, B.; Newlands, E S; Begent, R.H.; Rustin, G. J.; Bagshawe, K. D.

    1988-01-01

    Of 297 patients with metastatic testicular and extragonadal germ cell tumours (GCT), bone involvement was detected clinically in 3% (7/251) of those at first presentation and in 9% (4/46) of relapsed cases. This difference was not statistically significant (95% confidence limits -2%; +14%). Concurrent systemic metastases, commonly involving lung (7/11 cases) and para-aortic lymph nodes (6/11), were present in all patients with bone disease. All affected patients had localized bone pain and lu...

  16. Nuclear Factor-?B Activation in Human Testicular Apoptosis

    OpenAIRE

    Pentikäinen, Virve; Suomalainen, Laura; Erkkilä, Krista; Martelin, Eeva; Parvinen, Martti; Pentikäinen, Markku O.; Dunkel, Leo

    2002-01-01

    Apoptotic cell death plays an important role in limiting testicular germ cell population during spermatogenesis and its dysregulation has been shown to be associated with male infertility. The growing evidence on the role of the transcription factor nuclear factor (NF)-?B in controlling apoptosis prompted us to investigate NF-?B activity in the normal human testis and its role in testis tissue undergoing excessive apoptosis in vitro. In electrophoretic mobility shift assays, low-level constit...

  17. Medical image of the week: metastatic testicular cancer

    OpenAIRE

    Debo M; Snyder L; Rhodes SM

    2014-01-01

    A 30 year-old man with metastatic embryonal testicular cancer was admitted to the hospital with severe abdominal pain. A contrast enhanced CT of the abdomen demonstrated large metastatic burden throughout the liver and the left adrenal gland (Figures 1 and 2). The mass arising from the left adrenal gland caused significant mass effect. The left kidney was compressed, though without hydronephrosis, and the spleen was displaced laterally. Renal and hepatic functions were preserved. His pain was...

  18. Painless inter epididymal testicular torsion of the spermatic cord

    Directory of Open Access Journals (Sweden)

    Salomon V. Romano

    2007-02-01

    Full Text Available Inter epididymal testicular torsion of the spermatic cord is extremely rare and usually diagnosed at surgery. We present an unusual case of spermatic cord torsion in a 14-year-old male patient. It is important to highlight that the torsion occurred only on the distal half of the epididymis leaving the head untwisted and edematous. In addition, the fact that this condition was painless made this case extremely rare and motivated our presentation.

  19. Adolescent and adult risk factors for testicular cancer

    OpenAIRE

    McGlynn, Katherine A; Trabert, Britton

    2012-01-01

    The incidence of testicular cancer has been increasing over the past several decades in many developed countries. The reasons for the increases are unknown because risk factors for the disease are poorly understood. Some research suggests that exposures in utero or in early childhood are likely to be important in determining an individual's level of risk. However, other research suggests that exposure to various factors in adolecence and adulthood are also linked to the development of testicu...

  20. Ochratoxin A is not detectable in renal and testicular tumours

    Science.gov (United States)

    Fahmy, Nader; Woo, Mark; Alameldin, Mona; MacDonald, Kyle; Goneau, Lee W.; Cadieux, Peter; Pautler, Stephen E.

    2014-01-01

    Introduction: Ochratoxin-A (OTA) is one of the most abundant food-contaminating mycotoxins, known for its nephrotoxicity, neurotoxicity, gonadotoxicity, teratogenicity, immunosuppression and carcinogenesis. OTA has been linked to several genitourinary pathologies, including Balkan nephropathy and genitourinary malignancies. We examine OTA levels in serum samples and tumour specimens collected from patients with renal and testicular tumours. Methods: Frozen samples were obtained from the Ontario Tumour Bank. Serum specimens, along with renal and testicular tumour biopsies, were included in this study. Normal tissue from the negative surgical margins of each tumour served as a control. OTA levels in serum was measured using the enzyme-linked immunosorbent assay (ELISA), while OTA detection in tissue specimens was determined using immunohistochemistry (IHC). Results: We included specimens collected from 56 patients (36 men and 20 women). Histopathology of the 52 renal tumours included 31 (60%) conventional type renal cell carcinomas (RCC), 5 (10%) chromophobe RCC, 5 (10%) papillary RCC, 1 (2%) oncocytoma and 10 (19%) upper tract urothelial carcinoma (UC). The 4 testicular tumours included 1 seminomatous (25%) germ cell tumour and 3 (75%) non-seminomatous germ cell tumours. OTA was detected in the serum of renal tumour patients, with a range from 0.004 to 0.25 ng/mL (mean: 0.07 and median 0.06 ng/mL). There was no OTA signal detected by IHC staining in all tested renal and testicular tumours. Conclusions: The OTA levels detected in the serum of patients were highly variable and relatively low. No OTA was detected in the tissue samples. PMID:24578744

  1. Dietary Cholesterol-Induced Post-Testicular Infertility

    OpenAIRE

    Ouvrier, Aurélia; Alves, Georges; Damon-Soubeyrand, Christelle; Marceau, Geoffroy; Cadet, Rémi; Janny, Laurent; Brugnon, Florence; Kocer, Ayhan; Pommier, Aurélien; Lobaccaro, Jean-Marc A; Drevet, Joël R.; Saez, Fabrice

    2011-01-01

    This work shows that an overload of dietary cholesterol causes complete infertility in dyslipidemic male mice (the Liver X Receptor-deficient mouse model). Infertility resulted from post-testicular defects affecting the fertilizing potential of spermatozoa. Spermatozoa of cholesterol-fed lxr?/? animals were found to be dramatically less viable and motile, and highly susceptible to undergo a premature acrosome reaction. We also provide evidence, that this lipid-induced infertility is associate...

  2. ER? and ER? in mouse testicular cells and sperm.

    Czech Academy of Sciences Publication Activity Database

    Dostálová, Pavla; D?d, Lukáš; P?knicová, Jana

    Praha : Biotechnologický ústav, 2013 - (P?knicová, J.). s. 22-23 [XIX. Symposium imunologie a biologie reprodukce s mezinárodní ú?astí. 23.05.2013-25.05.2013, T?eš?] R&D Projects: GA ?R(CZ) GAP503/12/1834 Institutional research plan: CEZ:AV0Z50520701 Keywords : Estrogen receptor ? ? * Estrogen receptor ? * Testicular cells * Sperm atogenesis Subject RIV: EB - Genetics ; Molecular Biology

  3. A survey of etiologic hypotheses among testicular cancer researchers

    DEFF Research Database (Denmark)

    Stang, A; Trabert, B

    2015-01-01

    Basic research results can provide new ideas and hypotheses to be examined in epidemiological studies. We conducted a survey among testicular cancer researchers on hypotheses concerning the etiology of this malignancy. All researchers on the mailing list of Copenhagen Testis Cancer Workshops and corresponding authors of PubMed-indexed articles identified by the search term 'testicular cancer' and published within 10 years (in total 2750 recipients) were invited to respond to an e-mail-based survey. Participants of the 8th Copenhagen Testis Cancer Workshop in May 2014 were subsequently asked to rate the plausibility of the suggested etiologic hypotheses on a scale of 1 (very implausible) to 10 (very plausible). This report describes the methodology of the survey, the score distributions by individual hypotheses, hypothesis group, and the participants' major research fields, and discuss the hypotheses that scored as most plausible. We also present plans for improving the survey that may be repeated at a next international meeting of experts in testicular cancer. Overall 52 of 99 (53%) registered participants of the 8th Copenhagen Testis Cancer Workshop submitted the plausibility rating form. Fourteen of 27 hypotheses were related to exposures during pregnancy. Hypotheses with the highest mean plausibility ratings were either related to pre-natal exposures or exposures that might have an effect during pregnancy and in post-natal life. The results of the survey may be helpful for triggering more specific etiologic hypotheses that include factors related to endocrine disruption, DNA damage, inflammation, and nutrition during pregnancy. The survey results may stimulate a multidisciplinary discussion about new etiologic hypotheses of testicular cancer.

  4. Fisetin inhibits growth, induces G2/M arrest and apoptosis of human epidermoid carcinoma A431 cells: Role of mitochondrial membrane potential disruption and consequent caspases activation

    OpenAIRE

    Pal, Harish C.; Sharma, Samriti; Elmets, Craig A; Athar, Mohammad; Afaq, Farrukh

    2013-01-01

    Non-melanoma skin cancers (NMSCs) one of the most common neoplasms causes serious morbidity and mortality. Therefore, identification of non-toxic phytochemicals for prevention/treatment of NMSCs is highly desirable. Fisetin (3,3?,4?,7-tetrahydroxyflavone), a dietary flavonoid, present in fruits and vegetables possesses anti-oxidant and anti-proliferative properties. The aim of this study was to investigate the chemotherapeutic potential of fisetin in cultured human epidermoid carcinoma A431 c...

  5. Carcinoma Epidermoide Primario de la Mama: Una Infrecuente Entidad Clínico-Patológica Primary Squamous Cell Carcinoma of the Breast: A Rare Clinicopathological Entity

    OpenAIRE

    Oscar Tapia E

    2011-01-01

    El carcinoma epidermoide (CE) puro primario de la mama es una rara entidad clínico-patológica, que representa menos del 0,1% de todos los carcinomas de mama, conformada en su totalidad por células escamosas malignas que no presentan relación anatómica con la piel adyacente de la mama. Su etiopatogenia, pronóstico y tratamiento son motivo de controversias. Presentamos 1 caso de CE puros primario de la mama diagnosticado en la Unidad de Anatomía Patológica del Hospital Hernán Henríquez Aravena ...

  6. Stage 1 testicular seminoma; Seminomes testiculaire de stade 1

    Energy Technology Data Exchange (ETDEWEB)

    Gross, E.; Champetier, C.; Zaccariotto, A.; Duberge, T. [Departement de radiotherapie, hopital de la Timone, 13 - Marseille (France); Pointreau, Y. [Service de radiotherapie, centre regional universitaire de cancerologie Henry-S.-Kaplan CHU de Tours, Hpital Bretonneau, 37 - Tours (France); Chauvet, B. [Institut Sainte-Catherine, 84 - Avignon (France)

    2010-07-01

    Testicular cancer is rare, representing only 1 % of malignant tumors, but the most common cancer in young men, 15 to 35 years. Adjuvant radiotherapy after orchidectomy in testicular seminoma stage I, reduces risk of relapse. It aims to eradicate micro-metastatic disease in lymph drainage territories. In the case of adjuvant radiotherapy, the relapse-free survival of 96 % with an overall survival of 98 % at 5 years. The irradiation volume is made up of lymph nodes paraaortic which it is possible to add the ipsilateral renal hilum to the testicular lesion. The current recommended dose is 20 Gy in 10 fractions and 2 weeks, usually delivered by two antero-posterior beams. The acute toxicities, mainly represented by nausea and diarrhea are usually quickly resolved to the end of irradiation. Regarding toxicities long-term, preservation of semen should be considered after surgery because of fear of infertility post-treatment. The risk of second cancer associated with exposure to ionizing radiation, albeit small, is especially important to consider these patients to significant life expectancy. Nevertheless, developments in radiotherapy techniques and lower doses and irradiated volumes can probably reduce this risk further. (authors)

  7. Novel Tc-99m labeled ELR-containing 6-mer peptides for tumor imaging in epidermoid carcinoma xenografts model. A pilot study

    International Nuclear Information System (INIS)

    ELR-containing peptides targeting CXCR2 could be the excellent candidate for targeting ligand of molecular tumor imaging. In this study, we had developed two ELR-containing 6-mer peptides and evaluated the diagnostic performance of Tc-99m labeled 6-mer peptides as a molecular imaging agent in murine models bearing KB epidermoid carcinoma. Peptides were synthesized using Fmoc solid phase peptide synthesis. Radiolabeling efficiency with Tc-99m was evaluated using instant thin-layer chromatography. In KB epidermoid cancer-bearing mice, gamma images had acquired and tumor-to-muscle uptake ratio was calculated. Competition and biodistribution studies had performed. Two 6-mer peptides, ELR-ECG and ECG-ELR were successfully synthesized. After radiolabeling procedures with Tc-99m, the complex Tc-99m ELR-ECG and Tc-99m ECG-ELR were prepared in high yield. In the gamma camera imaging of murine model, Tc-99m ELR-ECG was substantially accumulated in the subcutaneously engrafted tumor and tumor uptake had been suppressed by the free ELR co-injection. However, Tc-99m ECG-ELR was minimally accumulated in the tumor. Two ELR-containing 6-mer peptides, ELR-ECG and ECG-ELR, were developed as a molecular imaging agent to target CXCR2 of epidermoid carcinoma. Tc-99m ELR-ECG had showed significant uptake in tumor and it was good candidate for a tumor imaging. (author)

  8. Detecção do rearranjo da proteína BCL2/JH em carcinomas epidermoides de boca e faringe / Detection of protein BCL2/JH rearrangement in epidermoid carcinomas of mouth and pharynx

    Scientific Electronic Library Online (English)

    Jair, Montovani; Magaly M, Sales; Maria Inês M C, Pardini.

    2010-09-01

    Full Text Available INTRODUÇÃO: A proteína BCL2 encontrada na membrana mitocondrial interna, regula a apoptose inibindo a morte celular programada. A translocação (14;18), detectada em 70 a 85% dos linfomas foliculares, leva a superexpressão da proteína BCL2, pela justaposição do gene BCL2 ao segmento JH do gene da cad [...] eia pesada da imunoglobulina. Porém, os achados da expressão da BCL2 em carcinoma de cabeça e pescoço são contraditórios. OBJETIVO: Investigar a presença da translocação (14;18) do gene BCL2 em carcinomas de cabeça e pescoço. MÉTODO: Foram examinadas 16 amostras de DNA, sendo 13 de carcinomas de células escamosas (CCE) e 3 de epidermoide (CE), por meio da reação em cadeia da polimerase (PCR). RESULTADOS: O rearranjo BCL2/JH foi encontrado em 2 (15%) dos 13 casos de CCE e em nenhum dos 3 casos de CE. A média de frequência de moléculas com rearranjo foi de 46,44 x 107. Não foi observada associação entre a presença de rearranjo e a exposição ao tabaco e álcool (p=0,6545). CONCLUSÃO: Diferente dos resultados encontrados em linfomas foliculares a presença da translocação (14;18) em carcinomas de cabeça e pescoço não é comum e, quando ocorre, pode ser uma mutação ocasional não associada a exposição ao tabaco e álcool. Abstract in english INTRODUCTION: The BCL2 protein found in the internal mothocondrial membrana regulates the apoptosis preventing the programmed cell death. The translocation (14:18), detected in 70 to 85% of the follicular lymphoma, lead the super expression of BCL2 protein, by juxtaposition of BCL2 gene to the JH se [...] gment of the immunoglobulins' heavy chain gene. However, the found of the BCL2 expression in head and neck carcinoma are contradictious. OBJECTIVE: To investigate the presence of the translocation (14:18) of the BCL2 gene in head and neck carcinoma. METHOD: Sixteen DNA samplers were examinated being 13 of squamous cells carcinoma (SCC) and 3 of epidermoid (CE), y means of chain reaction of the polymerase (PCR). RESULTS: The BCL2/JH rearrangement in 2 (15%) of the CCE 13 cases and in none of the 3 cases of CE. The average of the frequency of molecules with rearrangement was 46,44x107. Was not observed association between the rearrangement presence and the exhibition to tobacco and alcohol (p=0, 6545). CONCLUSION: Different from the results found in follicular lymphoma, the presence of the translocation (14; 18) in head and neck carcinomas is not common and, when it occurs, it can be an occasional mutation not associated to exhibition to the tobacco and alcohol.

  9. Immunohistochemistry Analysis of Proteins Related with Apoptosis as Prognostic Factor inEpidermoid Carcinomaof Penis / Análisis Inmunohistoquímico de Proteínas Relacionadas con la Apoptosis como Factor Pronóstico en el Carcinoma Epidermoide de Pene

    Scientific Electronic Library Online (English)

    P. C, Novais; A. A. P, de Paula; R. B, Reis; D. F, Barione; A. G, Franqueiro; A. A, Rodrigues Jr; F. S. N, Lizarte; C. A. M, de Carvalho; D. P. C, Tirapelli; F. M, Peria; F. P, Saggioro; S, Tucci Jr; A. J, Cologna; A. C. P, Martins; L. F, Tirapelli.

    2012-09-01

    Full Text Available El objetivo fue analizar la expresión de las proteínas de genes de apoptosis caspasa-3, caspasa-8 y Bcl-2-con la técnica de inmunohistoquímica, en correlación con el grado tumoral (I, II y III) y la supervivencia del paciente con el fin de comprender el mecanismo básico de la transformación tumoral. [...] Se analizaron las reacciones inmunohistoquímicas sobre 50 muestras de carcinoma de células escamosas mediante el método de la inmunoperoxidasa avidina-biotina y la recuperación de antígeno. Los análisis se realizaron utilizando el método de graduación "en cruces" (0 a 4 cruces - no tinción a más del 75% de las células positivas) y en categorías (baja, media, alta) de la inmunorreactividad citoplasmática de las células de carcinoma epidermoide de pene. Se observó una diferencia estadísticamente significativa cuando la expresión de la caspasa-3 se comparó con los grados I y II del tumor (p = 0,0010) y cuando se comparan la supervivencia de los pacientes con los grados I y II del tumor (p = 0,0212). La proteína bcl-2 se expresa más que la caspasa-3 y caspasa-8, lo que sugiere que la tasa de apoptosis en este carcinoma es baja. La mayor expresión de la proteína anti-apoptótica bcl-2 sugiere una mayor preservación de las células tumorales. Abstract in english The aim was to analyze the protein expression of apoptotic genes caspase-3, caspase-8 and bcl-2 with the immunohistochemistry technique, correlating with tumor grade (I, II and III) and with the patient survival in order to understand the basic mechanism of tumoral transformation. The immunohistoche [...] mistry reactions on 50 samples of squamous cell carcinoma were carried out with the avidin-biotin immunoperoxidase method and antigen recovery. The analyses were made using the graduation method "in crosses" (0 to 4 crosses - no stain to more than 75% of positives cells) and in categories (low, intermediate, high) of the cytoplasm immunoreactivity of the epidermoid penile carcinoma cells. It was observed a statistically significant difference when the expression of caspase-3 were compared with the grades I and II of the tumor (p=0.0010) and when comparing the patient survival with the grades I and II of the tumor (p=0.0212). The protein bcl-2 was more expressed than caspase-3 and caspase-8 proteins, suggesting that the apoptotic rate in this carcinoma is low. The higher expression of the anti-apoptotic protein bcl-2 suggests a higher preservation of the tumoral cells.

  10. BIOMETRIA TESTICULAR EM POTROS PURO SANGUE DE CORRIDA COM AUXÍLIO DO ULTRA-SOM / TESTICULAR BIOMETRICS IN THOROUGHBRED FOALS USING ULTRASOUND

    Scientific Electronic Library Online (English)

    Karin Erica, Brass; Joaquin Lopez de, Alda; Neiva Medianeira, Deprá; Flávio Desessards De La, Corte; José Henrique Souza da, Silva; Carlos Antonio Mondino, Silva.

    Full Text Available RESUMO Potros Puro Sangue de Corrida com idades variando de 2 a 24 meses foram submetidos a um estudo biométrico dos testículos com ultra-som. Observou-se um aumento no desenvolvimento testicular a partir dos 12 meses de idade e correlação altamente significativa entre o diâmetro testicular transver [...] sal (altura) e a idade. As imagens do parênquima testicular obtidas até os 5-6 meses de idade eram hipoecogênicas e com o avanço desta, aumentou a intensidade de reflexão até alcançar o padrão do parênquima testicular adulto. Abstract in english SUMMARY A biometric study wrth ultrasound was done in thoroughbred foals from 2 to 24 month old. From 12 month was observed an increase in the testicular development. Also, a significam correlation was found between the ultrasound measure of the transversal testicular diameter (height) and age. The [...] ultrasonographic image of the testicular parenchym was hypoechoic since 5-6 month. The reflexion rate increased u p to reach the adult pattern.

  11. Ecotoxicology and Testicular Damage (Environmental Chemical Pollution): A Review / Ecotoxicología y Daño Testicular. (Contaminación Química Ambiental): Revisión

    Scientific Electronic Library Online (English)

    Eduardo, Bustos-Obregón; Ricardo, Hartley B.

    2008-12-01

    Full Text Available Esta revisión considera el daño testicular provocado por la contaminación química ambiental. Incluye un breve comentario sobre toxicología ambiental a modo de introducción respecto a la polución química ambiental y destaca la importancia de este campo de estudio actual y su impacto sobre la salud re [...] productiva masculina. Además se presenta un modelo experimental animal concerniente al efecto de agropesticidas organofosforados como tóxicos testiculares. Se consideran dos contaminantes químicos relevantes y su efecto en el testículo como son el clásico caso del plomo y el menos conocido caso del boro y sus efectos sobre la espermatogénesis. También se trata el tema de las especies biocentinelas y su importancia para el monitoreo de la evolución de ecosistemas acuáticos y/o terrestres. En conclusión, es necesario insistir que la salud medioambiental está íntimamente relacionada con la salud reproductiva de todos los seres vivos. Abstract in english This review briefly considers the testicular damage elicited by environmental chemical pollution. It includes a short comment on environmental toxicology as an introduction to environmental chemical pollution, highlighting the importance of this current field of study and its impact on male reproduc [...] tive health. Furthermore an experimental animal model addressing the effect of organophosphorated agropesticides as a testicular toxicant is presented. Moreover two relevant chemical contaminants and their effect on the testis, such as the classical case of lead and the rarely reported case of Boron on spermatogenesis, are considered. Additionally, the subject of biosentinel species and their relevance for the monitoring of pollution in aquatic and/or terrestrial ecosystems is considered. In conclusión, it should be stressed that environmental health is closely related to the reproductive health of all living beings.

  12. Morfometria testicular de cabritos alimentados com óleo de licuri (Syagrus coronata) Testicular morphometry of goats fed licury (Syagrus coronata) oil

    OpenAIRE

    L.P Barbosa; Oliveira, R. L.; T. M. Silva; I.B Jesus; A.F. Garcez Neto; A.R Bagaldo

    2012-01-01

    Determinou-se o desenvolvimento testicular de caprinos pré-púberes alimentados com óleo de licuri (Syagrus coronata) na dieta. Foram utilizados 19 cabritos ¾ Boer, recém-desmamados, com média de idade de três meses. Os animais, submetidos a um período de 75 dias de confinamento, receberam alimentação composta por: farelo de milho, farelo de soja, feno picado de tifton 85 e de óleo de licuri com base na matéria seca. Os animais foram distribuídos em quatro grupos: sem lipídio adicional (n= 5);...

  13. Resultados de la Cirugía Laparoscópica en Quistes Hepáticos No Parasitarios / Results of Laparoscopic Surgery in Nonparasitic Hepatic Cysts

    Scientific Electronic Library Online (English)

    Carlos, Manterola.

    2013-09-01

    Full Text Available Los quistes hepáticos no hidatídicos (QHNH) se detectan de forma incidental, pueden ser únicos y múltiples. Desde que se describió el tratamiento laparoscópico de estos, se han reportado diversas series; existiendo por ende evidencia que avala la cirugía laparoscópica de estas lesiones. El objetivo [...] de este estudio, es reportar los resultados del tratamiento laparoscópico de QHNH en términos de morbilidad postoperatoria (MPO). Serie de casos. Se incluyeron pacientes intervenidos quirúrgicamente vía laparoscópica por QHNH en el Hospital Clínico de la Universidad Mayor entre enero de 2008 y diciembre de 2012. El estudio preoperatorio consistió en exámenes generales, determinación de ELISA-IgE e IgG para hidatidosis, ecotomografía abdominal o tomografía computarizada. En el período estudiado, se intervinieron 17 pacientes con QHNH, resecándose en ellos, un total de 39 quistes. El 76,5% de los casos eran de sexo femenino; y la mediana de edad de la serie fue de 56 años. La mediana del diámetro ecográfico de las lesiones fue de 7,5 cm. Se realizó quistectomía subtotal en todos ellos, sin utilización de drenaje. Se realizó epiploplastia en 4 pacientes. En el 82,4% de los casos se ejecutó de forma simultánea una colecistectomía por colelitiasis. La mediana del tiempo quirúrgico fue de 51 minutos. No fue necesario convertir a ningún paciente. La serie no registra MPO ni mortalidad. La mediana de estancia hospitalaria fue de 1 día. El estudio histopatológico confirmó "quiste de tipo biliar" en la totalidad de los casos. Con un seguimiento mínimo de 6 meses, no se ha evidenciado MPO tardía ni reaparición de las lesiones resecadas. El tratamiento aplicado a esta serie de casos de QHNH, se asocia a escasa estancia hospitalaria y buena evolución a corto y mediano plazo. Abstract in english Nonparasitic hepatic cysts (NPHC) can be detected incidentally, and may be single or multiple. Since described laparoscopic treatment of NPHC, several series have been reported, therefore there is enough evidence that support the role of laparoscopic surgery in the treatment of NPHC. The aim of this [...] study is to report the results of laparoscopic treatment of QHNH in terms of postoperative morbidity (POM). Case series. Patients operated laparoscopically by NPHC in the Universidad Mayor Clinical Hospital, Temuco, between January 2008 and December 2012 were included. The preoperative evaluation consisted of general exams, ELISA-IgE and IgG determination for hydatid disease, abdominal ultrasonography or abdominal CT scan. During the study period, 17 patients with NPHC were operated, resecting them a total of 39 cysts. 76.5% of patients were female, and the median age of the series was 56 years. The median sonographic diameter of the lesions was 7.5 cm. Subtotal cystectomy was performed in all of them, without using drainage. Epiploplasty was performed in 4 patients. In 82.4% of cases simultaneously cholecystectomy for cholelithiasis was performed. The median operative time was 51 minutes. Neither patient was converted. The series does not register MPO or mortality. The median hospital stay was 1 day. Histopathology confirmed the "biliary type cyst" in all cases. With a minimum follow up of 6 months, there is no evidence or late MPO or recurrence of the lesions resected. The treatment applied to this series of NPHC, is associated with short hospital stay and good outcome in the short and medium term.

  14. Quiste de conducto de Skene en niñas: A propósito de 2 casos clínicos / Skene duct cyst in female newborns: Case reports

    Scientific Electronic Library Online (English)

    Alberto, Miño Barrera; Jorge, Rodríguez Herrera.

    2014-10-01

    Full Text Available Introducción: El quiste del conducto de Skene, se describe dentro de los quistes parauretrales, siendo una rara anomalía congénita descrita en neonatos de sexo femenino, que se puede presentar en el transcurso de la vida. La incidencia varía de 1 cada 2.000-3.000 recién nacidos vivos femeninos. Obje [...] tivo: Dar a conocer las características y formas de presentación del quiste del conducto de Skene en distintas etapas del desarrollo del niño para su sospecha y diagnóstico oportuno. Casos clínicos: Se presenta una recién nacida con una lesión tumoral amarillenta, adyacente al meato uretral, no dolorosa, que drena espontáneamente y un segundo caso de una adolescente que consulto por leucorrea de un año de evolución, con una lesión parauretral de tres centímetros de diámetro entre labios menores, que requirió tratamiento quirúrgico y estudio de la masa parauretral. Conclusiones: Basado en la revisión de la literatura, concluimos que la frecuencia de los quistes de conducto de Skene es más alta que el número de casos informados. La extirpación, marsupialización, la punción y aspiración del quiste son todos métodos eficaces de tratamiento. El drenaje espontáneo también es una conducta apropiada en ciertos casos. Se sugiere utilizar la técnica menos agresiva acorde a cada caso. Abstract in english Introduction: The Skene duct cyst, classified as a paraurethral cyst, is a rare congenital abnormality in female neonates and it may manifest throughout the course of life. The incidence varies from 1 in 2000 to 3000 female births. Objective: To expose the characteristics and symptoms of a Skene duc [...] t cyst at different stages of child development in order to carry out a timely suspicion and diagnosis. Case report: The first case is a female newborn who presented a painless yellowish tumor adjacent to the urethral meatus, which drained spontaneously; the second case is a teenager who consulted due to leucorrhea for a year and a three-centimeter diameter paraurethral injury between the labia minora, which required surgical treatment and study of the paraurethral mass. Conclusions: Based on the literature review, we concluded that the frequency of Skene duct cyst is higher than the number of reported cases. Cyst removal, marsupialization, puncture and aspiration are all effective treatment methods. Spontaneous drainage is also appropriate in certain cases. We suggest the use of the least aggressive technique according to each case.

  15. Pathogenesis and Active Prevention of Testicular Germ Cell Neoplasia

    Directory of Open Access Journals (Sweden)

    Slowikowska-Hilczer J

    2007-01-01

    Full Text Available Most testicular neoplasms originate from fetal germ cells (germ cell tumors [GCT]. Intratubular germ cell neoplasia (ITGCN or testicular carcinoma in situ (CIS are terms used for the state when these cells are present in the seminiferous epithelium. The highest risk of neoplastic lesions occurs in testes with disturbed organogenesis (in our study, 65 %. Genetic, hormonal, and environmental factors are suspected to lead to disturbed testicular organogenesis (dysgenesis, which creates the milieu favorable for GCT development. An external environment can cause a block or delay in fetal germ and somatic cell differentiation. CIS cells in dysgenetic testes of children reveal a predominantly aneuploid DNA pattern (62.2?97.6 % of germ cells and they do not express an RBM protein (present in normal germ cells, this indicates that CIS cells are neoplastic from fetal life on. Most of the neoplastic germ cells die, however, some survive and proliferate, leading to a clonal expansion and giving rise to gonadoblastoma, CIS, and GCT. Neoplastic germ cells located inside underdeveloped testicular tubules have an intratesticular environment favorable for their survival ? this was confirmed by the finding that the highest incidence of neoplastic lesions occurred in patients with partial (90.9 % and mixed gonadal dysgenesis (76.9 %. It was hypothesized that the transformation of CIS into overt GCT may be promoted by gonadotropin action. We found that in gonadal dysgenesis, serum concentrations of FSH and LH reveal highly significant, positive correlations with the number of CIS cells, even in childhood. At present, surgical biopsy of the testis is the only reliable method to detect CIS and hence to actively prevent the development of overt GCT. Accordingly, early bilateral gonadectomy is recommended in all types of disturbance of testicular organogenesis because of the high risk of various neoplastic lesions in dysgenetic testes (86 % of adult patients with retained dysgenetic gonads developed GCT, CIS, gonadoblastoma or combinations. In other risk groups, the most frequently recommended method of CIS treatment is radiotherapy, with the exception of unilateral CIS, for which orchiectomy is the treatment of choice.

  16. Trombocitopenia severa como manifestación de un tumor testicular de células germinales con metástasis cardíaca intracavitaria / Testicular tumor with intracardiac metastasis presenting as severe thrombocytopenia

    Scientific Electronic Library Online (English)

    Germán, Armijo; Patricio, Sanhueza; Marcelo, Morales; Claudio, de la Vega; Alejandro, Ceballos; Carlos, Orfali.

    Full Text Available Se describe el caso de un hombre de 24 años que se presenta con Púrpura trombocitopénico, cuyo estudio ecocardiográfico y tomografía computada demostró masa tumoral ocupando las cavidades derechas. Se evidenció posteriormente un tumor testicular izquierdo con componentes de seminoma y teratoma. Se r [...] esecó el tumor testicular y posteriormente el tumor intracardíaco, con normalización del recuento plaquetario. Abstract in english A 24 year old man presented with severe thrombocytopenia. An intracardiac mass was shown to be a metastasis from a malignant testicular tumor. Resection of the primary tumor and the intracardiac metastasis led to full recovery of thrombocytopenia. [...

  17. Goat scrotal-testicular biometry: Influence of the season on scrotal bipartition / Biometria escroto-testicular em caprinos: influência de período do ano na bipartição escrotal

    Scientific Electronic Library Online (English)

    Antonio A.N., Machado Júnior; Antonio C., Assis Neto; Carlos E., Ambrósio; Rudolf, Leiser; Gustavo S., Lima; Leonardo S., Oliveira; Maria A.M., Carvalho.

    2011-12-01

    Full Text Available Objetivou-se neste trabalho avaliar a biometria escroto-testicular em caprinos com escroto simples e bipartido, criados no Estado do Piauí, Brasil, nos períodos seco e chuvoso do ano. Foram utilizados 18 caprinos machos, divididos em três grupos de seis caprinos. O grupo I (escroto sem bipartição), [...] o grupo II (escroto bipartido até 50% de comprimento testicular) e o grupo III (bipartição escrotal superior a 50% do comprimento testicular). A biometria escroto-testicular consistiu do comprimento escrotal (COE), circunferência escrotal (CE), comprimento testicular (CT) e volume testicular (V). Os resultados foram submetidos à análise de variância (ANOVA), seguido do teste SNK para comparação das médias. Os dados mostraram que os animais do grupo GIII apresentaram, no período seco, os valores de CE, COE, CT e V de 24,63cm, 16,61cm, 5,32cm, e 173,81cm³, respectivamente e de 26,97cm para CE, 18,24cm para COE, 5,93cm para CT e 203,01cm³ para V, no período chuvoso. Todos esses valores foram superiores (p Abstract in english The scrotal-testicular biometry was evaluated in goats raised in Piaui state, Brazil, presenting different levels of scrotal division, in rainy and dry periods of the year. For this study, eighteen male goats at mating age were accomplished and arranged into three groups (6 animals each), obeying th [...] e classification as goats with no scrotal bipartition (GI), goats showing scrotal bipartition up to 50% of testicular length (GII), and goats with more than 50% of scrotal bipartition (GIII). The biometry of the scrotal-testicular was made evaluating the scrotal length (SL), scrotal circumference (SC), testicular length (TL) and testicular volume (TV). The results were evaluated following the variance analysis (ANOVA) and the SNK test applied on the average comparisons. The analysis of the data demonstrated high values, in dry and rainy periods, of SC (24.63cm/ 26.97cm), SL (16.61cm/ 18.24cm), TL (5.32cm/ 5.93cm), TV (173.81cm³/ 203.01cm³). This supports the hypothesis of the influence of the period of the year and of the scrotal bipartition on the scrotal-testicular biometry in goat.

  18. Corporal and testicular biometry in wild boar from birth to 12 months of age / Biometria corporal e testicular de javalis do nascimento aos 12 meses de idade

    Scientific Electronic Library Online (English)

    Danillo Velloso Ferreira, Murta; Deiler Sampaio, Costa; Marcelo Diniz, Santos; Fábio José Carvalho, Faria; Tarcízio Antônio Rêgo de, Paula.

    2013-02-01

    Full Text Available Objetivou-se, com esta pesquisa, investigar o desenvolvimento testicular e corporal de javalis (Sus scrofa scrofa), do nascimento aos 12 meses de idade, avaliando-se, em cada faixa etária, o peso corporal, o desenvolvimento biométrico dos testículos e o índice gonadossomático (IGS). Utilizaram-se 52 [...] javalis machos, provenientes de um criatório comercial, devidamente regulamentado pelo IBAMA. Os animais foram pesados e divididos em 13 grupos experimentais; os testículos foram coletados por orquiectomia unilateral e, em seguida, pesados em balança analítica e mensurados comprimento, largura e espessura. Os valores de peso corporal e as medidas testiculares foram crescentes, após o nascimento, sendo sua variação mais acelerada no primeiro mês e aos nove meses. Inicialmente, o padrão de crescimento testicular, do nascimento aos nove meses de idade, acompanhou o crescimento corporal e o índice gonadossomático variou de 0,07 a 0,09%. Em seguida, entre nove e 11 meses, o valor de crescimento testicular foi superior ao de crescimento corporal e o índice gonadossomático variou de 0,09 a 0,16%. Por fim, após os 11 meses de idade, os valores crescimento corporal e dos testículos voltaram a se comportar de forma semelhante. Conclui-se que o desenvolvimento do peso corporal, a biometria testicular e o IGS tiveram crescimento mais acelerado aos nove meses de idade. Abstract in english The aim of this tudy was to evaluate corporal and testicular development in wild boars (Sus scrofa scrofa) from birth to 12 months of age, evaluating body weight, biometric testicular parameters, and gonadosomatic index. Thirty-nine male wild boars from a commercial farm licensed by IBAMA were used [...] in the study. The animals were weighed and assigned to 13 experimental groups. The testes were recovered through unilateral orchiectomy, weighed on an analytical balance and measured for length, width and thickness. Body weight and testicular measures increased with the age, up to 12 months, and were more accelerated in the first and ninth months. Initially the testicular growth pattern, between zero and nine months, followed the body growth, and the gonadosomatic index varied from 0.07 to 0.09%. Between 9 and 11 months, the testicular growth was superior to the body growth, and the gonadosomatic index varied from 0.09 to 0.16%. Finally, after 11 months of age, testicular and body growth had a similar behavior. In conclusion, body weight, testicular biometry, and gonadosomatic index development accelerated in the ninth month.

  19. Diagnóstico en Torsión de Pedículo de Quiste Anexial en Ginecología / Diagnosis in torsion of adnexal cyst in gynecology

    Scientific Electronic Library Online (English)

    Freddy, Maita Q.; Erwin, Hochstatter Arduz; Oscar, Niño de Guzman Peña.

    Full Text Available Objetivos: Evaluar los signos clínicos, ecográficos y Doppler color en el diagnóstico de la torsión de pedículo. Métodos: Estudio observacional prospectivo de corte transversal, incluyó a 22 pacientes durante un período de tres años, que acudieron, con dolor abdominal agudo y presencia de quiste ane [...] xial. Las edades comprendidas fueron entre 22 y 58 años. Resultados: Cotejados con los hallazgos quirúrgicos y la evolución clínica: de 22 pacientes, 9 tenían torsión de pedículo; la tríada clásica mostró una sensibilidad de 55%, especificidad del 46%, valor predictivo positivo del 42%, valor predictivo negativo del 60%. El signo directo de torsión de pedículo mostró una sensibilidad de 78%, especificidad de 92%, valor predictivo positivo de 87%, valor predictivo negativo del 86%. El Doppler color mostró una sensibilidad de 100%, especificidad de 69%, valor predictivo positivo de 69%, valor predictivo negativo de 100%. El líquido libre abdominal mostró un resultado variable. Conclusiones: La sospecha clínica es el primer paso en el diagnóstico; el hallazgo del signo directo de torsión fue el de mayor valor diagnóstico; el hallazgo de señal Doppler color en la pared del quiste prácticamente, descartó la posibilidad de torsión. Abstract in english Objectives: To evaluate the clinical, ultrasonography signs and Doppler color in the diagnosis of the torsión of pedicle. Methods: Prospective observational study of cross-section included 22 patients over a period of three years, who attended with acute abdominal pain and presence of anexial cyst. [...] With an age range between 22 and 58 years. Results: 22 patients, 9 had torsión of pedicle; triad classic showed a 55% sensitivity, specificity 46%, positive predictive value 42%, negative predictive value 60%. The direct sign of torsión of pedicleshowed a sensitivity of 78%, specificity 92%, positive predictive value 87%,negative predictive value of 86%. The absence of Doppler signal colorshowed a sensitivity of 100%, specificity of 69%, positive predictive value 69%, negative predictive value of 100%. The abdominal free liquid showed a variable result. Conclusions: The clinical suspicion is the first passage in the diagnosis; the finding of the direct sign of torsión was the one of greater value diagnosis; the finding of color Doppler signal in the wall of the cyst practically, discarded any possibility of torsion.

  20. Carcinoma epidermoide oral y orofaríngeo: Estudio clínico-patológico Oral and oropharingeal squamous cells carcinoma: Clinico-pathological study

    Directory of Open Access Journals (Sweden)

    Pablo Guzmán G

    2011-06-01

    Full Text Available Introducción: El cáncer oral es una enfermedad frecuente en muchas partes del mundo, en Chile corresponde al 1,6% del total de cánceres. La gran mayoría corresponde a carcinoma epidermoide, con importantes diferencias clínicas, epidemiológicas y patológicas entre las localizaciones labial, intraoral y orofaríngea. Objetivo: Analizar las características clínicas y patológicas del carcinoma epidermoide oral y orofaríngeo en Temuco, Chile. Material y Método: Estudio descriptivo, retrospectivo de todos los casos diagnosticados en 15 años (1994 y 2008, en el Hospital Regional de Temuco. Los pacientes fueron analizados de acuerdo a género, edad, y los tumores fueron clasificados basados en su localización anatómica, tamaño, características macroscópicas y grado de diferenciación. Resultados: Se encontraron 93 carcinomas, con relación hombre:mujer de 5:1, edad promedio 67 años. Pacientes menores a 50 años correspondían sólo al 8% de los casos. Las localizaciones más frecuentes fueron labio inferior, lengua y encía, con un tamaño promedio de 28 mm, el que aumentó hacia la orofarinx, más de la mitad eran moderadamente diferenciados. Conclusiones: En nuestra región, este carcinoma afecta con mayor frecuencia a la séptima década de la vida y a población masculina y posee características similares a las descritas en otros países donde predomina la raza blanca. El tamaño al diagnóstico es considerable. La detección de algunas diferencias en el grupo con apellidos mapuches amerita un estudio con un mayor número de casos.Introduction: Oral cancer is a common disease in many parts of the world, in Chile only accounts for 1.6% of all cancers. The majority is squamous cell carcinoma with important clinical, epidemiological and pathological differences between lip, oral and orofaringeal locations. Objective: To analyze clinical and pathological characteristics of oral and oropharingeal squamous cell carcinoma in Temuco, Chile. Materials and Methods: A descriptive, retrospective study of all diagnosed cases in 15 years (1994 and 2008. The patients were analyzed according to gender, age; and the tumors were classified based on anatomic location, size, macroscopical findings and degree of differentiation. Results: We found 93 carcinomas, with male to female ratio of 5:1, average age 67 years. Patients under 50 years accounted for only 8% of cases. The most common sites were lower lip, tongue and gingiva, with an average size of 28 mm, which increased towards orofarinx and more than half were moderately differentiated. Conclusions: In our region, this carcinoma most often affects the seventh decade of life and male population and has similar characteristics to those in other countries which is predominantly. The size at diagnosis is significant. The detection of some differences in the group with mapuche surnames warrants a study with a larger number of cases.

  1. Carcinoma epidermoide oral y orofaríngeo: Estudio clínico-patológico / Oral and oropharingeal squamous cells carcinoma: Clinico-pathological study

    Scientific Electronic Library Online (English)

    Pablo, Guzmán G; Miguel, Villaseca H; Lilia, Antonio P; Juan, Araya O; Paola, Aravena M; Carla, Cravero P; Pilar, Pino M; Juan, Roa S.

    2011-06-01

    Full Text Available Introducción: El cáncer oral es una enfermedad frecuente en muchas partes del mundo, en Chile corresponde al 1,6% del total de cánceres. La gran mayoría corresponde a carcinoma epidermoide, con importantes diferencias clínicas, epidemiológicas y patológicas entre las localizaciones labial, intraoral [...] y orofaríngea. Objetivo: Analizar las características clínicas y patológicas del carcinoma epidermoide oral y orofaríngeo en Temuco, Chile. Material y Método: Estudio descriptivo, retrospectivo de todos los casos diagnosticados en 15 años (1994 y 2008), en el Hospital Regional de Temuco. Los pacientes fueron analizados de acuerdo a género, edad, y los tumores fueron clasificados basados en su localización anatómica, tamaño, características macroscópicas y grado de diferenciación. Resultados: Se encontraron 93 carcinomas, con relación hombre:mujer de 5:1, edad promedio 67 años. Pacientes menores a 50 años correspondían sólo al 8% de los casos. Las localizaciones más frecuentes fueron labio inferior, lengua y encía, con un tamaño promedio de 28 mm, el que aumentó hacia la orofarinx, más de la mitad eran moderadamente diferenciados. Conclusiones: En nuestra región, este carcinoma afecta con mayor frecuencia a la séptima década de la vida y a población masculina y posee características similares a las descritas en otros países donde predomina la raza blanca. El tamaño al diagnóstico es considerable. La detección de algunas diferencias en el grupo con apellidos mapuches amerita un estudio con un mayor número de casos. Abstract in english Introduction: Oral cancer is a common disease in many parts of the world, in Chile only accounts for 1.6% of all cancers. The majority is squamous cell carcinoma with important clinical, epidemiological and pathological differences between lip, oral and orofaringeal locations. Objective: To analyze [...] clinical and pathological characteristics of oral and oropharingeal squamous cell carcinoma in Temuco, Chile. Materials and Methods: A descriptive, retrospective study of all diagnosed cases in 15 years (1994 and 2008). The patients were analyzed according to gender, age; and the tumors were classified based on anatomic location, size, macroscopical findings and degree of differentiation. Results: We found 93 carcinomas, with male to female ratio of 5:1, average age 67 years. Patients under 50 years accounted for only 8% of cases. The most common sites were lower lip, tongue and gingiva, with an average size of 28 mm, which increased towards orofarinx and more than half were moderately differentiated. Conclusions: In our region, this carcinoma most often affects the seventh decade of life and male population and has similar characteristics to those in other countries which is predominantly. The size at diagnosis is significant. The detection of some differences in the group with mapuche surnames warrants a study with a larger number of cases.

  2. Re-irradiation combined with local hyperthermia of unresectable nodal recurrences of head and neck epidermoid carcinomas. Reirradiation combinee a une hyperthermie locale des recidives ganglionnaires inoperables des carcinomes epidermoides des voies aerodigestives superieures

    Energy Technology Data Exchange (ETDEWEB)

    Prevost, B.; Mirabel, X. (Centre de Lutte Contre le Cancer Oscar-Lambret, 59 - Lille (France)); Giaux, G. (Clinique Medicale Bourgogne, 59 - Lille (France)); Chive, M. (Lille-1 Univ., 59 - Villeneuve-d' Ascq (France)); Sozanski, J.P.; Gombert-Leveque, C.

    1993-01-01

    From 1985 to 1989, we treated, in a phase II clinical trial, 50 isolated unresectable nodal recurrences of head and neck epidermoid carcinomas in previously irradiated fields. The median diameter of these nodes was 4.5 cm (3-6 cm). Local hyperthermia was achieved in all patients with a 13.56 MHz radio frequency capacity system. A hyperthermia session was carried out for 60 min just after each radiation treatment, twice a week. The median total number of sessions was 17 (10-20). Radiation therapy (electron beams) was administered with the aim of avoiding damage to previously irradiated tissues. The dose per fraction at the point of maximum dose was 4 Gy (the target dose at 90% depth was 3.6 Gy). The mean target total dose at 90% depth was 54 Gy (32-60). With this combined treatment, the overall response rate was 88% without toxicity. A local control (NED) was observed in 18/50 (36%) patients. The 2-year survival rate for this group was 27% (Kaplan Meier). The acute toxicity was mild in spite of the fact that these patients had previously received radiation treatment. The late reactions were not markedly exacerbated as compared to the initial situation. Radiation therapy combined with local hyperthermia seems to be a safe form of treatment for these unresectable and isolated nodal recurrences of head and neck carcinomas.

  3. Neonatal outcome and congenital malformations in children born after ICSI with testicular or epididymal sperm : a controlled national cohort study

    DEFF Research Database (Denmark)

    Fedder, Jens; Loft, A

    2013-01-01

    Does neonatal outcome including congenital malformations in children born after ICSI with epididymal and testicular sperm [testicular sperm extraction (TESE)/percutaneous epididymal sperm aspiration (PESA)/testicular sperm aspiration (TESA) (TPT)] differ from neonatal outcome in children born after ICSI with ejaculated sperm, IVF and natural conception (NC)?

  4. A genome-wide association study of men with symptoms of testicular dysgenesis syndrome and its network biology interpretation

    DEFF Research Database (Denmark)

    Dalgaard, Marlene D.; Weinhold, Nils; Edsgärd, Daniel; Silver, Jeremy David; Pers, Tune H.; Nielsen, John E.; Jørgensen, Niels; Juul, Anders; Gerds, Thomas Alexander; Giwercman, Aleksander; Giwercman, Yvonne L.; Cohn-Cedermark, Gabriella; Virtanen, Helena E.; Toppari, Jorma; Daugaard, Gedske; Jensen, Thomas Skøt; Brunak, Søren; Rajpert-De Meyts, Ewa; Skakkebæk, Niels E.; Leffers, Henrik; Gupta, Ramneek

    2012-01-01

    Testicular dysgenesis syndrome (TDS) is a common disease that links testicular germ cell cancer, cryptorchidism and some cases of hypospadias and male infertility with impaired development of the testis. The incidence of these disorders has increased over the last few decades, and testicular cancer now affects 1% of the Danish and Norwegian male population.

  5. TB or not TB?: a case of isolated testicular TB with scrotal involvement.

    LENUS (Irish Health Repository)

    Bhargava, A

    2009-06-01

    Despite the genitourinary tract being the most common site affected by extrapulmonary TB, isolated testicular TB remains a rare clinical entity. In patients with co-morbidities such as hepatic impairment, treatment proves a challenge, as first-line hepatotoxic pharmaceuticals are contraindicated. Here, we report a case of isolated testicular TB with scrotal involvement, on a background of hepatic dysfunction.

  6. Glioblastoma multiforme after radiotherapy for metastatic brain tumor of testicular cancer

    Energy Technology Data Exchange (ETDEWEB)

    Saiki, Shigeru; Kinouchi, Toshiaki; Usami, Michiyuki; Nakagawa, Hidemitsu; Kotake, Toshihiko [Osaka Medical Center for Cancer and Cardiovascular Diseases (Japan)

    1997-09-01

    A patient with left testicular cancer and metastases to retroperitoneal lymph nodes, lung, and brain was treated by chemotherapy, radiotherapy and surgery, and obtained the state of no evidence of disease, but 10 years after radiotherapy, a glioblastoma multiforme tumor appeared in the brain. This is the first report of a glioma appearing after radiotherapy in a testicular cancer patient. (author)

  7. Exaggerated prolactin response to thyrotropin-releasing hormone and metoclopramide in primary testicular failure.

    Science.gov (United States)

    Spitz, I M; LeRoith, D; Livshin, Y; Zylber-Haran, E; Trestian, S; Laufer, N; Ron, M; Palti, Z; Schenker, J

    1980-12-01

    Twenty-eight severely oligospermic and azoospermic men aged 20 to 42 years were challenged with luteinizing hormone (LH)-releasing hormone (LHRH), thyrotrophin-releasing hormone (TRH), and the dopaminergic antagonist, metoclopramide, given at 30-minute intervals. According to basal gonadotropin levels, the patients were subdivided into three groups: those with severe testicular failure (basal LH > 20 mIU/ml and FSH > 14 mIU/ml); those with moderate testicular failure with predominant seminiferous tubule involvement (LH 14 mIU/ml) and those with mild testicular failure (LH < 20 mIU/ml and FSH < 14 mIU/ml. With one exception, mean basal prolactin (PRL) levels were normal in all patients. In all three groups, however, there was an exaggerated PRL response to TRH, the response in severe and moderate testicular failure being greater than that in mild testicular failure. The response to metoclopramide was increased only in the first two groups, not in the group with mild testicular failure. When individual patients and control subjects were considered together, the peak PRL response to TRH correlated with both basal and peak gonadotropin responses to LHRH. However, the PRL responses did not correlate with 17 beta-estradiol, estrone, testosterone, or the estradiol-testosterone ratio. It is concluded that oligospermic and azoospermic subjects with the most severe testicular failure and the highest gonadotropin levels have the greatest PRL increases after TRH and metoclopramide, indicating that the PRL response is related to the degree of testicular failure. PMID:6778717

  8. Quiste laríngeo congénito: Una rara causa de estridor en niños Congenital Laryngeal Cyst: A Rare Cause of Stridor in Children

    Directory of Open Access Journals (Sweden)

    Rodrigo Iñiguez C

    2006-04-01

    Full Text Available Introducción: Los quistes laríngeos congénitos (QLC son una causa rara de estridor en niños. Objetivo: Describir las características clínicas del QLC como responsable de estridor atípico. Caso clínico: Una lactante sana fue evaluada por cuadro agudo de disfonía y estridor asociado a dificultad respiratoria progresiva en ausencia de pródromo respiratorio viral. La nasofibrolaríngoscopía demostró una masa en el ventrículo laríngeo y pliegue aritenoepiglótico izquierdo de 1 cm. La tomografía computada sugirió un QLC único, por lo que se procedió a marsupialización con resección de sus paredes. La evolución fue favorable, con controles posteriores hasta por 3 meses, observando una progresiva disminución del proceso inflamatorio. Conclusiones: Los QLC son una causa de estridor atípico que requieren alta sospecha. Se resalta la necesidad de considerar el estudio anatómico de la vía aérea en todo niño con estridor de curso infrecuenteBackground: Congenital laryngeal cyst (CLC is a rare cause of stridor in children. Objective: To describe the clinical profile of atypical stridor due to CLC. Case report: A healthy infant was admitted for acute dysphonia, stridor and progressive respiratory distress without previous respiratory infection. A nasofiberoptic evaluation showed a laryngeal ventricle and a left aritenoepyglotic mass. The scanner revealed a unique CLC. A marsupialization was performed with resection of the walls. She had a successful ambulatory assessment of 3 months. Conclusion: CLC causes an atypical stridor that requires a high suspicious index. Under special situations, an airway evaluation should be considered as essential for the management

  9. Quiste dentígeno gigante en una niña: Presentación de un caso / Giant dentigerous cyst in a girl: Case report

    Scientific Electronic Library Online (English)

    Juan Carlos, Quintana Díaz; Abdulsalam, Ali Zwiad; Sarah, López Lazo; Sergio, Vega Basulto; Rafael, Pinilla González; Zayed, Hussein.

    2007-06-01

    Full Text Available Se presenta un caso interesante de una niña de 13 años que acude a la consulta de Cirugía Maxilofacial por presentar asimetría facial y bucal, además de referir diplopia y obstrucción nasal del lado de la deformidad. Después de realizar exámenes de laboratorio, radiográficos y tomografía axial compu [...] tadorizada (TAC), se lleva al salón de operaciones para realizar extracción del tercer molar superior izquierdo retenido en posición invertida, enuclear la extensa área radiolúcida a los rayos X y radiopaca a la tomografía y posteriormente se realiza estudio histopatológico. El diagnóstico definitivo corroboró el presuntivo (quiste dentígeno ). La paciente evolucionó de forma excelente; desaparecieron la deformidad facial y los demás síntomas preoperatorios. Abstract in english An interesting case of a 13 year-old girl comes to Maxillofacial Surgery consultation because she has facial and buccal asymmetry; she also refers diplopia and nasal obstruction on the side of the deformity. After carrying out laboratory exams, radiographic studies and computerized axial tomography [...] (TAC), she was taken to the operating room to receive an extraction of the third left superior molar retained in inverted position, and to have retrieved the extensive rays- X radiolucid and radiopaque area at tomography and later on she underwent a histopathological study. The definitive diagnosis corroborated the presumption of dentition cyst. The patient evolved in an excellent way; her facial deformity and other preoperative symptoms disappeared.

  10. Thiol protease-specific inhibitor E-64 arrests human epidermoid carcinoma A431 cells at mitotic metaphase

    International Nuclear Information System (INIS)

    E-64-d /ethyl (2S, 3S)-3-[(S)-3-methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl]oxirane-2-carboxylate/, a membrane-permeant derivative of the thiol protease-specific inhibitor E-64, was found to arrest human epidermoid carcinoma A431 cells at mitotic metaphase. This effect was dose-dependent with a threshold of 20?g/ml in chemically defined culture medium. Cell cycle analysis by flow cytometry showed that the relative proportion of the G2/M population increased 2.5-fold after treatment of the cells with E-64 (100 ?g/ml) for 5 hr. In addition, time-lapse video analysis showed that E-64-treated cells remained at metaphase for an extended period after rounding-up, whereas untreated cells were able to complete mitosis within 42.0 +/- 5.7 min. Some treated cells were able to complete mitosis, while others did not do so within limits of the authors observation. An approach to the molecular basis of this phenomenon, they have shown that several cellular proteins can be labeled by incubation of cells with radioactive E-64-d

  11. Isolated ectopic production of the free beta subunit of chorionic gonadotropin by an epidermoid carcinoma of unknown primary site.

    Science.gov (United States)

    Nagelberg, S B; Marmorstein, B; Khazaeli, M B; Rosen, S W

    1985-05-01

    Metastatic choriocarcinoma was suspected in a 39-year-old woman who presented 7 months postpartum with fatigue, pelvic pain, a massive pleural effusion, and a positive urine pregnancy test. Subsequent evaluation resulted in discovery of the isolated production of the free beta-subunit of chorionic gonadotropin (CG-beta) by a widespread, poorly differentiated epidermoid carcinoma. Chemotherapy was ineffective, the woman died, and at autopsy the primary site of the tumor could not be determined. The patient's serum (185 ng/ml) and a tumor metastasis (720 ng/g) contained large amounts of immunoactive material that diluted in parallel to CG-beta standard, but neither chorionic gonadotropin (CG), its alpha subunit, nor other placental proteins were detected. A monoclonal antibody that recognizes free CG-beta, but not intact CG, was instrumental in implicating an ectopic source of the CG-beta before a tissue diagnosis was obtained. When the patient's serum was chromatographed on a dextran gel, the CG-beta immunoactivity eluted in a position of higher apparent molecular weight than either standard CG or CG-beta, suggesting that this neoplasm secreted an altered molecular form of the CG-beta subunit. PMID:4038915

  12. Study of the Effect of the Cytotoxic Extract of Bacterium Streptomyces on Epidermoid Malignant Cells of the Oral Cavity

    Directory of Open Access Journals (Sweden)

    M Farahmand

    2004-07-01

    Full Text Available Introduction: It is well known that marine microorganisms have been recognized as an important and untapped resource for novel bioactive compounds. Actinomycetes are gram positive bacteria showing a filamentous growth. They are a group of organisms widespread in nature and play a significant role in the future of drug development. Materials & Methods : Marine bacteria strains of Streptomyces griscoloalbus were isolated from soft coral Sinularia erecta in Persian Gulf. Growth and fermentation character of the Streptomyces griscoloalbus were estimated. Cytotoxic activity of fermentation medium was tested by brine shrimp bioassay. Semi purification on the culture extract was performed. Results: Toxic extract was applied on KB cells ( human epidermoid carcinoma of mouth and results of neutral red test were IC50= 4.19 g/ml from acetone extract and IC 50 = 44.97 g/ml. For methanol extract, cytotologic effects of the acetone extract on KB cells was studied and morphological changes were also studied. Conclusion:The morphological changes in Kb cells due to the cytotoxic extract of the bacteria has made it a good candidate for the production of cytotoxic drugs in the future.

  13. DOUBLE RIGHT TESTICULAR ARTERI ES WITH ITS EMBRYOLOGICAL BASIS: A CASE REPORT

    Directory of Open Access Journals (Sweden)

    Anita Shriram

    2015-07-01

    Full Text Available Variations in the origin of arteries in the abdomen are very common but with the advent of new operative and laparoscopic techniques within the abdominal cavity, the anatomy of the abdominal vessels has assumed much more clinical importance. During routine dissection for MBBS of the abdominal cavity, we came across double right testicular arteries in a middle aged male cadaver. Testicular arterial morphology deviating from its normal anatomy is a serious concern, as diagnostic approaches in male infertility and varicocele can be often linked with its associated vascular anomaly. The origin and course of the testicular artery must be carefully identified in order to preserve normal blood circulation and prevent testicular atrophy. Radiologists, urologists and oncologists should be famil iar with testicular artery variants in order to provide an accurate diagnosis during pre - operative studies. Knowledge of this variation will help to avoid clinical complications especially during radiological examination and/or surgical approaches in abdom inal region.

  14. Expression patterns of DLK1 and INSL3 identify stages of Leydig cell differentiation during normal development and in testicular pathologies, including testicular cancer and Klinefelter syndrome

    DEFF Research Database (Denmark)

    Lottrup, G; Nielsen, J E; Maroun, L L; Møller, L M A; Yassin, M.; Leffers, H; Skakkebæk, N E; Rajpert-De Meyts, E

    2014-01-01

    STUDY QUESTION: What is the differentiation stage of human testicular interstitial cells, in particular Leydig cells (LC), within micronodules found in patients with infertility, testicular cancer and Klinefelter syndrome? SUMMARY ANSWER: The Leydig- and peritubular-cell populations in testes with dysgenesis contain an increased proportion of undifferentiated cells when compared with control samples, as demonstrated by increased delta-like homolog 1 (DLK1) and decreased insulin-like peptide 3 (I...

  15. Avaliação histomorfométrica do parênquima testicular de ratos adultos tratados com diferentes doses de ivermectina Histomorphometric evaluation of testicular parenchyma of adult rats treated with different dosages of ivermectin

    OpenAIRE

    Moura, C S; M.M.P. Guerra; V.A. Silva Júnior; C.G.C. Silva; F.M. Caju; L.C. Alves

    2006-01-01

    Avaliou-se o efeito da ivermectina sobre o parênquima testicular através da produção espermática diária e da eficiência da espermatogênese em ratos Wistar adultos tratados com diferentes dosagens (200, 400 e 600µg/kg). Pela avaliação histomorfométrica, o parênquima testicular e o processo espermatogênico dos ratos Wistar não sofreram qualquer efeito deletério da aplicação de ivermectina, o que foi confirmado pela manutenção da produção espermática diária por testículo, pelo rendimento intríns...

  16. Testicular parenchymal abnormalities in Klinefelter syndrome: a question of cancer? Examination of 40 consecutive patients

    Directory of Open Access Journals (Sweden)

    Giacomo Accardo

    2015-02-01

    Full Text Available Klinefelter syndrome (KS is a hypergonadotropic hypogonadism characterized by a 47, XXY karyotype. The risk of testicular cancer in KS is of interest in relation to theories about testicular cancer etiology generally; nevertheless it seems to be low. We evaluated the need for imaging and serum tumor markers for testicular cancer screening in KS. Participants were 40 consecutive KS patients, enrolled from December 2009 to January 2013. Lactate dehydrogenase (LDH, alpha-fetoprotein (AFP, and beta-human chorionic gonadotrophin subunit (?-HCG serum levels assays and testicular ultrasound (US with color Doppler, were carried out at study entry, after 6 months and every year for 3 years. Abdominal magnetic resonance (MR was performed in KS when testicular US showed micro-calcifications, testicular nodules and cysts. Nearly 62% of the KS had regular testicular echotexture, 37.5% showed an irregular echotexture and 17.5% had micro-calcifications and cysts. Eighty seven percent of KS had a regular vascular pattern, 12.5% varicocele, 12.5% nodules 1 cm. MR ruled out the diagnosis of cancer in all KS with testicular micro calcifications, nodules and cysts. No significant variations in LDH, AFP, and ?-HCG levels and in US pattern have been detected during follow-up. We compared serum tumor markers and US pattern between KS with and without cryptorchidism and no statistical differences were found. We did not find testicular cancer in KS, and testicular US, tumor markers and MR were, in selected cases, useful tools for correctly discriminating benign from malignant lesions.

  17. Immunoreactivity examination of patients with testicular tumours treated with radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Stefanits, K.; Kuhn, E.; Csere, T.

    1985-02-01

    Results of the immunoreactivity study of 72 patients receiving radiotherapy are presented. Tuberculin and DNCB (2,4 dinitrochlorobenzol) reactivity tests were performed before, during and 3 years after the radiation therapy and at the time when metastases appeared. The number of positive reactions decreased slightly in both tuberculin and DNCB groups, though not significantly. Metastatic patients showed a significant decrease of reactivity against DNCB as compared with the results obtained before the treatment. In 5,6% of patients herpes zoster was registered. No other infections occured. It was found that immunosuppression caused by the radiation treatment does not influence the later fate of patients with testicular tumours. 41 refs.

  18. Medical image of the week: metastatic testicular cancer

    Directory of Open Access Journals (Sweden)

    Debo M

    2014-06-01

    Full Text Available A 30 year-old man with metastatic embryonal testicular cancer was admitted to the hospital with severe abdominal pain. A contrast enhanced CT of the abdomen demonstrated large metastatic burden throughout the liver and the left adrenal gland (Figures 1 and 2. The mass arising from the left adrenal gland caused significant mass effect. The left kidney was compressed, though without hydronephrosis, and the spleen was displaced laterally. Renal and hepatic functions were preserved. His pain was controlled with opioids and oral steroids with significant improvement.

  19. Effect of zearalenone on expression of testicular genes in vivo.

    Czech Academy of Sciences Publication Activity Database

    Žatecká, Eva; D?d, Lukáš; Dvo?áková, Eva; Dorosh, Andriy; Elzeinová, Fatima; P?knicová, Jana

    Praha : Biotechnologický ústav v. v. i. AV ?R, 2012 - (P?knicová, J.). s. 44-44 [XVIII. symposium ?eských reproduk?ních imunolog? s mezinárodní ú?astí. 25.05.2012-26.05.2012, Ž?ár nad Sázavou] R&D Projects: GA ?R(CZ) GA523/09/1793; GA ?R(CZ) GAP503/12/1834 Institutional research plan: CEZ:AV0Z50520701 Keywords : zearalenone * testicular gene * gene expression * endocrine disruptor * PCR Subject RIV: DN - Health Impact of the Environment Quality

  20. XX testicular disorder of sex differentiation: case report

    Directory of Open Access Journals (Sweden)

    Bianca Bianco

    2011-09-01

    Full Text Available The 46 XX, testicular sex differentiation disorder, or XX malesyndrome, is a rare condition detected by cytogenetics, in whichtesticular development occurs in the absence of the Y chromosome.It occurs in 1:20,000 to 25,000 male newborns and represents 2%of cases of male infertility. About 90% of individuals present withnormal phenotype at birth and are generally diagnosed after pubertyfor hypoganadism, gynecomastia, and/or infertility. The authorspresent the report of an XX male with complete masculinization andinfertility.

  1. Torsión testicular perinatal: resultados de 10 años de experiencia Perinatal testicular torsion: results of 10 years of experience

    Directory of Open Access Journals (Sweden)

    Sara López Calimano

    2011-12-01

    Full Text Available Introducción: la torsión testicular perinatal es definida como la torsión del testículo en período prenatal, o dentro de los primeros 28 días de vida. Objetivo: evaluar los datos obtenidos de las historias clínicas, y proponer principios de tratamientos clínicos y quirúrgicos. Métodos: fueron revisadas retrospectivamente las historias clínicas de los recién nacidos operados con diagnóstico de torsión testicular en el servicio de cirugía pediátrica del Hospital Pediátrico "William Soler", entre enero de 2000 y diciembre de 2009. Resultados: 18 pacientes fueron elegibles para el estudio, 17 tenían torsión unilateral con testículo aumentado de tamaño duro e indoloro (94 %, 55 % tenían hidrocele contralateral, 16 pacientes nacieron a término, con más de 3 100 g de peso (88 %, y la torsión extravaginal y la afectación del testículo izquierdo se observó en 13 (72 %. Un caso fue bilateral asincrónico (6 %, pues el testículo izquierdo estaba torcido en la región inguinal, isquémico, pero no necrótico, y fue preservado. Dos casos (12 % tenían torsión de tipo intravaginal, y uno de ellos se presentó, clínicamente, como escroto agudo. Se diagnosticó la afección en edades de 0 a 7 días en el 72 % de los casos. Se realizó orquiectomía sin exploración contralateral a 16 pacientes (88 %. La evolución fue satisfactoria en 17 (94 %. Conclusiones: la torsión testicular perinatal representa el 3,4 % de las afecciones quirúrgicas neonatales, y puede afectar un testículo no descendido. Se sugiere protocolizar el uso del ultrasonido doppler preoperatorio, y la exploración y fijación del testículo contralateral.Introduction: the perinatal testicular torsion is defined as a twist of testicle in prenatal period or within the first 28 days of life. Objective: to assess the data obtained from the medical records and to propose the principles of clinical and surgical treatments. Methods: retrospectively the medical records of newborn operated on diagnosed with testicular torsion were reviewed admitted in the pediatric surgery service of the "William Soler" Teaching Children Hospital from January, 2000 to December, 2009. Results: eighteen patients were eligible for study, 17 had a unilateral torsion with a testicle of increase size, hard and painless (94 %, the 55 % had contralateral hydrocele, 16 patients born at term weighing more than 3 100 g (88 %, the extravaginal torsion and left testicle involvement was observed in 13 (72 %. A case had bilateral asynchronism (6 %, since the left testicle was twisted in the inguinal region with ischemia but not necrosis and could be preserved. Two cases (12 % had torsion of intravaginal type and one of them was clinically presented as acute scrotum. The affection was diagnosed in ages from 0 to 7 days in the 72 % of cases. An orchiectomy was performed without contralateral exploration in 16 patients (88 %. Evolution was satisfactory in 17 cases (94 %. Conclusions: the perinatal testicular torsion accounts for the 3,4 % of neonatal surgical affections and may to involve a und-descent testicle. Authors suggest making a protocol of preoperative Doppler ultrasound and the exploration and fixation of contralateral testicle.

  2. Torsión testicular perinatal: resultados de 10 años de experiencia / Perinatal testicular torsion: results of 10 years of experience

    Scientific Electronic Library Online (English)

    Sara, López Calimano; Juana Rosa, López Esquirol; Pedro Abelardo, Vilorio Barreras.

    2011-12-01

    Full Text Available Introducción: la torsión testicular perinatal es definida como la torsión del testículo en período prenatal, o dentro de los primeros 28 días de vida. Objetivo: evaluar los datos obtenidos de las historias clínicas, y proponer principios de tratamientos clínicos y quirúrgicos. Métodos: fueron revisa [...] das retrospectivamente las historias clínicas de los recién nacidos operados con diagnóstico de torsión testicular en el servicio de cirugía pediátrica del Hospital Pediátrico "William Soler", entre enero de 2000 y diciembre de 2009. Resultados: 18 pacientes fueron elegibles para el estudio, 17 tenían torsión unilateral con testículo aumentado de tamaño duro e indoloro (94 %), 55 % tenían hidrocele contralateral, 16 pacientes nacieron a término, con más de 3 100 g de peso (88 %), y la torsión extravaginal y la afectación del testículo izquierdo se observó en 13 (72 %). Un caso fue bilateral asincrónico (6 %), pues el testículo izquierdo estaba torcido en la región inguinal, isquémico, pero no necrótico, y fue preservado. Dos casos (12 %) tenían torsión de tipo intravaginal, y uno de ellos se presentó, clínicamente, como escroto agudo. Se diagnosticó la afección en edades de 0 a 7 días en el 72 % de los casos. Se realizó orquiectomía sin exploración contralateral a 16 pacientes (88 %). La evolución fue satisfactoria en 17 (94 %). Conclusiones: la torsión testicular perinatal representa el 3,4 % de las afecciones quirúrgicas neonatales, y puede afectar un testículo no descendido. Se sugiere protocolizar el uso del ultrasonido doppler preoperatorio, y la exploración y fijación del testículo contralateral. Abstract in english Introduction: the perinatal testicular torsion is defined as a twist of testicle in prenatal period or within the first 28 days of life. Objective: to assess the data obtained from the medical records and to propose the principles of clinical and surgical treatments. Methods: retrospectively the med [...] ical records of newborn operated on diagnosed with testicular torsion were reviewed admitted in the pediatric surgery service of the "William Soler" Teaching Children Hospital from January, 2000 to December, 2009. Results: eighteen patients were eligible for study, 17 had a unilateral torsion with a testicle of increase size, hard and painless (94 %), the 55 % had contralateral hydrocele, 16 patients born at term weighing more than 3 100 g (88 %), the extravaginal torsion and left testicle involvement was observed in 13 (72 %). A case had bilateral asynchronism (6 %), since the left testicle was twisted in the inguinal region with ischemia but not necrosis and could be preserved. Two cases (12 %) had torsion of intravaginal type and one of them was clinically presented as acute scrotum. The affection was diagnosed in ages from 0 to 7 days in the 72 % of cases. An orchiectomy was performed without contralateral exploration in 16 patients (88 %). Evolution was satisfactory in 17 cases (94 %). Conclusions: the perinatal testicular torsion accounts for the 3,4 % of neonatal surgical affections and may to involve a und-descent testicle. Authors suggest making a protocol of preoperative Doppler ultrasound and the exploration and fixation of contralateral testicle.

  3. OPTIMIZACIÓN EN LA ESTRATEGIA DIAGNÓSTICA Y TERAPÉUTICA EN EL QUISTE DE COLÉDOCO / Optimization in diagnostic and therapeutic strategy of choledochal cyst

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    Grecia Victoria, Vivas-Colmenares; Ana, Millán-López; Juan Carlos, De Agustín A.

    2015-06-01

    Full Text Available Objetivos: El quiste de colédoco presenta una incidencia de 1 en 100.000-150.000. El propósito de este estudio fue analizar las variables introducidas para la optimización en el diagnóstico y tratamiento del quiste de colédoco. Material y Métodos: Estudio retrospectivo de pacientes intervenidos en n [...] uestro centro de quiste de colédoco mediante hepático-yeyunostomía en Y de Roux, desde septiembre de 1988 a noviembre de 2012. Se analizan 40 variables incluyendo edad, sintomatología, tipo de quiste, pruebas diagnósticas, cambios en la técnica quirúrgica, complicaciones y evolución. Resultados: 18 pacientes (66,6% mujeres) fueron agrupados de acuerdo a la edad de presentación: Prenatal ( 24 meses). Los síntomas más frecuentes fueron ictericia y dolor abdominal (para los de inicio precoz y tardío respectivamente). El 83,3% presentaban quistes de colédoco tipo I; siendo suficiente la ecografía para el diagnóstico en el 94,4%. A partir de 2004 modificamos la técnica quirúrgica, realizando por vía laparoscópica la disección de la vía biliar y mediante laparotomía mínima (3-5 cm) hepático-yeyunostomía con asa descendente de 40 cm, empleando sutura de polipropileno, observando desde el 2004, sólo 1 dehiscencia parcial de la anastomosis, resuelta con tratamiento conservador y 1 colangitis en paciente con poliquistosis hepática y renal. En el año 2012 el 83,3% están asintomáticos. Conclusiones: El diagnóstico se ha simplificado, en más de 90% de los casos se realiza sólo con ecografía; los avances en cirugía mínimamente invasiva y la creación de asa descendente de 40 cm, han logrado optimizar el pronóstico del quiste de colédoco. Abstract in english Objectives: The choledochal cyst has an incidence of 1 in 100.000-150.000. The purpose of this study was to analyze the variables introduced for the optimization in the diagnosis and treatment of choledochal cyst. Material and Methods: Retrospective study of patients treated in our center by hepatic [...] -jejunostomy and Roux-Y, from September 1988 to November 2012. We analyzed 40 variables including age, symptoms, type of cysts, diagnostic tests, changes in surgical technique, complications and outcomes. Results: Eighteen patients (66.6% female) were grouped according to the age of presentation: Prenatal ( 24 months). The most common symptoms were jaundice and abdominal pain (for early-onset and late-onset respectively). The 83.3% presented choledochal cysts type I, the ultrasound was sufficient for diagnosis in 94.4%. Since 2004 we modified the surgical technique, performing laparoscopic dissection of the bile duct and cyst, adding a mini-laparotomy (3-5 cm) for hepatic-jejunostomy with 40 cm intestinal loop using polypropylene suture. One complication was observed since 2004, one case of partial dehiscence of the anastomosis resolved with conservative treatment and a cholangitis in 1 patient with hepatic and renal polycystic. In 2012, 83.3% are asymptomatic. Conclusions: The diagnostic have been simplified, in more than 90% of cases was done by ultrasound; advances in minimally invasive surgery and creation of descending loop of 40 cm, have helped to improve the prognosis of choledochal cyst.

  4. Quiste coloide del tercer ventrículo. Presentación de un caso: una nueva alternativa en el tratamiento de las ectasias / Colloidal cyst of the third ventricle. Case presentation

    Scientific Electronic Library Online (English)

    Ada, Sánchez Lozano; María, Rodríguez Roque; Joan, Rojas Fuentes.

    2009-08-01

    Full Text Available Los quistes coloides son lesiones intracraneales congénitas benignas, de la porción antero-superior del tercer ventrículo. Suponen del 0,2 al 2 % de todos los tumores intracraneales y representan del 15 al 20 % de todas las masas intraventriculares. Comienzan a ser sintomáticos en la adolescencia o [...] edad adulta temprana, generalmente con manifestaciones de cefalea o síntomas de hipertensión intracraneal al provocar hidrocefalia obstructiva. Se presenta una adolescente de 18 años con historia de cefalea de 2 años de evolución, cuyos síntomas fueron empeorando en intensidad y frecuencia, acompañados de vómitos y parestesias bilaterales; se le diagnosticó hidrocefalia obstructiva con quiste coloide del tercer ventrículo. Ante la sospecha del diagnóstico se tomó una conducta adecuada, para evitar el deterioro neurológico y la muerte. Se discutieron las principales características del quiste coloide, su cuadro clínico y radiológico. Abstract in english Colloidal cysts are congenital intracranial benign lesions of the anterior superior portion of the third ventricle. They represent between the 0,2 and 2 % of all the intracranial tumours and represent the 15 or 20 % of all the intraventricular masses. They become symptomatic during the adolescence o [...] r early adulthood and start normally with migraine or symptoms of intracranial hypertension causing obstructive hydrocephaly. We present the case of a teenager of 18 years of age with history of migraine after two years and the symptoms worsened in intensity and frequency including vomiting and bilateral paresthesia; the diagnosis was obstructive hydrocephaly with colloidal cyst of the third ventricle. An appropriate practice was adopted due to the uncertain diagnosis in order to avoid neurological damage and death. We discussed the main characteristics of the colloidal cyst, its clinical presentation and radiological characteristics and we performed.

  5. Diagnóstico por imagen de un quiste hidatídico pulmonar gigante. Reporte de un caso clínico / Diagnostic imaging of a giant pulmonary hydatid cyst. Clinical Case Report

    Scientific Electronic Library Online (English)

    Ifigenia, Oviedo Gamboa; Boris Jorge, Castillo Yujra; William, Zegarra Santiesteban; José Luis, Llanos Fernández.

    2013-06-01

    Full Text Available La Hidatidosis o equinococcosis es una enfermedad clasificada dentro de las ciclozoonosis. Es producida por las formas larvarias de Echinococcus granulosus que parasita el intestino del perro. Los quistes hidatídicos poseen como segunda localización el pulmón en un 10%. Se presenta el caso clínico d [...] e una paciente de 82 años de edad que presento un cuadro clínico de 1 mes de evolución caracterizado por accesos de tos productiva verdosa, escalofríos, alzas térmicas , al examen físico se auscultó murmullo vesicular disminuido en campo pulmonar izquierdo. Se realizó radiografía de tórax inconclusas donde se evidencio dos imágenes radiopacas circulares, homogéneas , en cuadrante superior e inferior de campo pulmonar izquierdo. La tomografía multicorte informo quistes pulmonares gigantes en he-mitorax izquierdo, se realizo toracotomía exploratoria y quistectomia, finalmente la patología confirmo quistes hidatídicos pulmonares gigantes y proceso inflamatorio crónico activo. Abstract in english Hydatidosis or echinococcosis is a disease classified within ciclozoonosis. It is produced by the larval forms of Echinococcusgranulosus that parasitizes the intestine of the dog. Hydatid cysts cover the lung with 10%, beeingthe second location. This is a case report of a patient of 82 years old who [...] had a 1 month clinical evolution characterized by greenish productive coughing, chills, heat rises , physical examination decreased breath sounds auscultated in left lung field, The X ray (unfinished) evidenced two circular homogeneousradio-pacities upper quadrant and lower left lung field, multislice CT reported giant lung cysts, exploratory thoracotomy and cystectomy was performed, finally pathology confirmed pulmonary giant hydatid cysts and active chronic inflammatory process.

  6. Quiste de la glándula de skene: 4 casos y revision de literatura / Cyst of the skene's gland: Report of four cases and bibliographic review

    Scientific Electronic Library Online (English)

    Luis, Busto Martín; lyad, Barguti; Antón, Zarraonandia Andraca; Ignacio, Rodríguez Gómez; Luis, Busto Castañón.

    2010-04-01

    Full Text Available Objetivos: Presentar nuestra experiencia con cuatro casos de quistes de las glándulas de Skene de gran tamaño, realizar una revisión de la literatura publicada y conocer así los distintos diagnósticos diferenciales y el manejo a seguir. Métodos: Cuatro mujeres remitidas a nosotros desde su ginecólog [...] o por presentar masas parauretrales refractarias a tratamiento conservador con posible afectación de la uretra distal. Conclusiones: El quiste de la glándula de Skene es una patología que raramente tratan los urólogos debido a su escasa repercusión clínica pero cuando nos es remitida por los ginecólogos es importante realizar un estudio completo del aparato urinario para realizar así un diagnóstico diferencial certero que excluya patologías malignas o alteraciones del aparato urinario. El tratamiento de elección en los casos refractarios es quirúrgico, realizando una exéresis completa del quiste y reparando las posibles lesiones de la pared uretral. En todos los casos la evolución fue favorable sin presentar recidiva o complicaciones fistulosas. Abstract in english Objectives: To show our experience with 4 cases of cysts of the Skene's gland and a review of the published literature. Methods/results: Diagnosis and treatment of 4 cases of Skene's gland cyst. Conclusions: Skene's gland cyst is a lesion that rarely is treated by Urologists, because it doesn't usua [...] lly have clinical repercussion, but when it's derived to us we have to make a complete study of the urinary tract to exclude complications or different serious lesions. Surgery is the treatment of choice, making a complete excision of the lesion and repair of urethral injuries. All cases evolved well without recurrence or fistulous complications.

  7. Quiste parauretral de Skene en niña recién nacida / The paraurethral cyst or skene´s duct cyst in the female newborn

    Scientific Electronic Library Online (English)

    A., Parente-Hernández; J.Mª. A., Angulo-Madero; , del Cañizo-López; O., Sánchez-París; R.M., Romero-Ruiz; J., Vázquez-Estévez.

    2006-01-01

    Full Text Available El quiste parauretral o quiste del conducto de Skene es una rara anomalía congénita descrita en neonatos de sexo femenino. Se trata de una formación quística que se muestra como una tumoración redonda, amarillenta o anaranjada, que se presenta adyacente al meato externo uretral. Su incidencia en la [...] población se cifra entre 1 de cada 2.000 y 1 de cada 7.000 recién nacidos vivos femeninos. Sin embargo, sólo se recogen 47 ejemplos anteriores en la literatura en inglés. Es posible que el desconocimiento de esta patología entre la población médica y su benignidad produzcan fallos diagnósticos que infravaloren esta incidencia. Aunque existen autores que apoyan el tratamiento quirúrgico del quiste para lograr su curación, más aún a partir de los 6 meses de edad, la mayoría se ponen de acuerdo en la indicación de un tratamiento expectante dada la tendencia a la resolución espontánea. Abstract in english The paraurethral cyst or Skene´s duct cyst is a rare congenital anomaly in the female newborn. It appears like a round, yellow or orange-colored cystic mass on either side of the urethral meatus. The reported incidence is 1 in 2.000 to 7.000 female births. The low frequency of the Skene´s duct cyst [...] and the little awareness of it and its benignity may lead to wrong diagnosis that underestimates its incidence. There are authors that agree with surgical treatment of paraurethral cyst to obtain an early resolution, even though a majority agrees to manage conservatively.

  8. Histogenesis of Testicular Parenchyma During Prenatal Life in Buffalo / Histogénesis del Parénquima Testicular Durante la Vida Intrauterina en el Búfalo

    Scientific Electronic Library Online (English)

    Manjinder, Kaur; Neelam, Bansal; Varinder, Uppal.

    2011-12-01

    Full Text Available El estudio fue realizado en los testículos de 18 fetos de búfalos, para revelar la histogénesis y diferenciación de las diferentes células de parénquima testicular. A los 8,0 cm de longitud corona-rabadilla (LCR) (65 días) los túbulos seminíferos estuvieron presentes en la periferia de la gónada y u [...] na red poligonal de células mesenquimales se observó en el centro del testículo. Estos túbulos estaban rodeados por una membrana basal y una sola capa de células peritubular a los 10 cm LCR (74 días), la cual se convirtió en una doble capa a los 88,0 cm LCR (272 días). El parénquima testicular a 12,0 cm LCR tenía dos zonas, zona exterior con túbulos longitudinales y zona interior con los túbulos redondeados transversalmente. Sin embargo, un patrón inverso en su disposición se observó a los 14,0 cm LCR (92 días). Las células pre-Sertoli se observaron primero en fetos de búfalos de 8,0 cm LCR (65 días) en la periferia del epitelio seminífero tubular, mientras que los gonocitos fueron visibles en el centro de los túbulos a 10,6 cm LCR (76 días). Las células de Leydig fetales también se observaron a los 8,0 cm LCR (65 días), pero a los 14,0 cm LCR (92 días), el intersticio tuvo una considerable expansión debido a la diferenciación de células mesenquimales en células de Leydig. Abstract in english The study was conducted on the testes of 18 buffalo foetii to reveal histogenesis and differentiation of different cells of testicular parenchyma. At 8.0 cm CVR (65 days) the seminiferous tubules were present at gonadal periphery and a network of polygonal mesenchymal cells was seen in the centre of [...] testis. These tubules were surrounded by a distinct basement membrane and a single layer of peritubular cells at 10 cm CVR (74 days), which became double layered at 88.0 cm CVR (272 days). The testicular parenchyma at 12.0 cm CVR had two zones; outer zone having longitudinal tubules and inner zone having rounded tubules. But a reverse pattern of their arrangement was observed at 14.0 cm CVR (92 days). The pre-Sertoli cells were first observed in buffalo foetii of 8.0 cm CVR (65 days) in the periphery of seminiferous tubular epithelium whereas the gonocytes were demonstrable in the centre of tubules at 10.6 cm CVR (76 days). The fetal Leydig cells were also reported at 8.0 cm CVR (65 days) but at 14.0 cm CVR (92 days), the interstitium had considerably expanded due to the differentiation of mesenchymal cells into the Leydig cells.

  9. Histogenesis of Testicular Parenchyma During Prenatal Life in Buffalo Histogénesis del Parénquima Testicular Durante la Vida Intrauterina en el Búfalo

    Directory of Open Access Journals (Sweden)

    Manjinder Kaur

    2011-12-01

    Full Text Available The study was conducted on the testes of 18 buffalo foetii to reveal histogenesis and differentiation of different cells of testicular parenchyma. At 8.0 cm CVR (65 days the seminiferous tubules were present at gonadal periphery and a network of polygonal mesenchymal cells was seen in the centre of testis. These tubules were surrounded by a distinct basement membrane and a single layer of peritubular cells at 10 cm CVR (74 days, which became double layered at 88.0 cm CVR (272 days. The testicular parenchyma at 12.0 cm CVR had two zones; outer zone having longitudinal tubules and inner zone having rounded tubules. But a reverse pattern of their arrangement was observed at 14.0 cm CVR (92 days. The pre-Sertoli cells were first observed in buffalo foetii of 8.0 cm CVR (65 days in the periphery of seminiferous tubular epithelium whereas the gonocytes were demonstrable in the centre of tubules at 10.6 cm CVR (76 days. The fetal Leydig cells were also reported at 8.0 cm CVR (65 days but at 14.0 cm CVR (92 days, the interstitium had considerably expanded due to the differentiation of mesenchymal cells into the Leydig cells.El estudio fue realizado en los testículos de 18 fetos de búfalos, para revelar la histogénesis y diferenciación de las diferentes células de parénquima testicular. A los 8,0 cm de longitud corona-rabadilla (LCR (65 días los túbulos seminíferos estuvieron presentes en la periferia de la gónada y una red poligonal de células mesenquimales se observó en el centro del testículo. Estos túbulos estaban rodeados por una membrana basal y una sola capa de células peritubular a los 10 cm LCR (74 días, la cual se convirtió en una doble capa a los 88,0 cm LCR (272 días. El parénquima testicular a 12,0 cm LCR tenía dos zonas, zona exterior con túbulos longitudinales y zona interior con los túbulos redondeados transversalmente. Sin embargo, un patrón inverso en su disposición se observó a los 14,0 cm LCR (92 días. Las células pre-Sertoli se observaron primero en fetos de búfalos de 8,0 cm LCR (65 días en la periferia del epitelio seminífero tubular, mientras que los gonocitos fueron visibles en el centro de los túbulos a 10,6 cm LCR (76 días. Las células de Leydig fetales también se observaron a los 8,0 cm LCR (65 días, pero a los 14,0 cm LCR (92 días, el intersticio tuvo una considerable expansión debido a la diferenciación de células mesenquimales en células de Leydig.

  10. ¿Los quistes renales simples son otra forma de manifestación de prelitiasis en la infancia? / Are simple renal cysts another manifestation of prelithiasis in infancy?

    Scientific Electronic Library Online (English)

    Víctor, García Nieto; K., Dublan García; M.I., Luis Yanes.

    Full Text Available Los quistes renales simples son lesiones poco frecuentes en pacientes pediátricos. En ausencia de hipopotasemia o de un incremento en la producción de NH4+, se desconoce el origen de los mismos. Hepler, en 1930, propuso que su causa podría ser una obstrucción tubular. Hemos estudiado de forma prospe [...] ctiva la presencia de hipercalciuria o de hipocitraturia, así como los antecedentes familiares de litiasis en un grupo de niños diagnosticados ecográficamente de quistes renales simples. Al diagnóstico, la edad media de los 22 pacientes (12 varones y 10 mujeres) fue de 6,04 ± 2,9 años. El estudio ecográfico se había solicitado por infección de vías urinarias, dolor abdominal, hematuria u otros. Los quistes fueron ligeramente más frecuentes en el lado izquierdo (54,5%). Todos estaban ubicados en el polo renal superior. En 14 pacientes (63,6%) se demostró que eran portadores de hipercalciuria o hipocitraturia (hipercalciurian = 11, 50%). En 13 familias existían antecedentes de litiasis renal. En conjunto, las anomalías metabólicas estudiadas causantes de cálculos en los niños o los antecedentes familiares de litiasis estaban presentes en 19 familias (86,3%). Nuestra hipótesis es que ambas entidades, quistes renales y predisposición genética a padecer cálculos renales, están relacionadas. Abstract in english Simple renal cysts are uncommon lesions in paediatric patients. In the absence of hypokalaemia or an increase in the production of NH+, the cause of simple renal cysts is unknown. Hepler, in 1930, suggested that they may be caused by a tubular obstruction. We prospectively studied the presence of hy [...] percalciuria or hypocitraturia as well as the family history of urolithiasis in a group of children diagnosed sonographically with simple renal cysts. The average age of the 22 patients (12M, 10F) was 6.04 ± 2.9 years at the time of diagnosis. The ultrasound examination had been requested due to urinary tract infection, abdominal pain, haematuria or other disorders. The cysts were slightly more frequent on the left side (54.5%). All were located in the upper kidney pole. 14 patients were found to have hypercalciuria and/or hypocitraturia (hypercalciuria n = 11, 50%). Thirteen families had history of renal stones. The metabolic abnormalities associated with calculi in children and/or family history of stones were present in 19 families (86.3%). Our hypothesis is that both entities, renal cysts, and genetic predisposition to kidney stones, are related.

  11. Perfil epidemiológico, clínico y terapéutico de los quistes odontogénicos en Santiago de Cuba / Epidemiological, clinical therapeutic profile of odontogenic cysts in Santiago de Cuba

    Scientific Electronic Library Online (English)

    José Manuel, Díaz Fernández; Luis Emilio, Puig Ravinal; Carmen Beatriz, Vives Folgar.

    2014-01-01

    Full Text Available Se realizó un estudio descriptivo, prospectivo y longitudinal de 230 quistes odontogénicos de la cavidad bucal, intervenidos quirúrgicamente en el Servicio de Cirugía Maxilofacial del Hospital Provincial Docente Clinicoquirúrgico "Saturnino Lora de Santiago de Cuba, en el período 2000-2008, con vist [...] as a caracterizarles desde los puntos de vista clínico, epidemiológico y terapéutico. Entre los resultados principales sobresalió que los quistes inflamatorios presentaron mayor incidencia que los de desarrollo, en una proporción 1,8:1. Ambos grupos de quiste prevalecieron en el sexo masculino, con proporción de 2,4:1 en relación con el femenino. La edad promedio general fue de 38,4±11,2 años (con un rango entre 18 y 71 años) y el tamaño de 3,01±1,54 cm. Hubo predominio de los quistes de la mandíbula en dichos grupos, siendo los sectores de bicúspides molares (maxilar superior) y el área del tercer molar inferior los más afectados. La técnica de tratamiento de elección resultó ser la quistectomía, asociada o no a material de relleno en la cavidad quística. El índice general de recidiva fue bajo y la quistotomía presentó mayor porcentaje, a causa de los queratoquistes. Las complicaciones peroperatorias y posoperatorias indicaron una morbilidad baja Abstract in english A descriptive, prospective, longitudinal study of 230 odontogenic cysts of the oral cavity was carried out, which were surgically treated in the Maxillofacial Surgery Department of "Saturnino Lora” Provincial Teaching Clinical Surgical Hospital of Santiago de Cuba, from 2000 to 2008, to characterize [...] them from the clinical, epidemiological and therapeutic points of view. The main results revealed a higher incidence of inflammatory cysts than development cysts, with ratio of 1.8:1. Male sex prevailed in both groups, with ratio of 2.4:1 relative to female sex. The overall mean age was 38.4±11.2 years (with a range between 18 and 71 years) and the size of 3.01±1.54 cm. There was a prevalence of mandibular cysts in these groups, being the areas of molar bicuspids (maxilla) and of lower third molar the most affected. The technique of choice treatment was cystectomy, associated or not with filling in cystic cavity. Overall recurrence rate was low and cystotomy had a higher percentage due to keratocysts. Peroperative and postoperative complications showed low morbidity

  12. Quiste odontogénico calcificante asociado con odontoma complejo: Presentación de un caso y revisión bibliográfica / Calcifying odontogenic cyst associated with complex odontoma: Case report and review of the literature

    Scientific Electronic Library Online (English)

    Silvia, Gallana Alvarez; Francisco, Mayorga Jimenez; Francisco Javier, Torres Gómez; Francisco Javier, Avellá Vecino; Clara, Salazar Fernandez.

    2005-07-01

    Full Text Available Se presenta un caso de quiste odontogénico calcificante asociado con odontoma (QOCaO) y con un canino permanente incluido en maxilar superior, en un paciente varón de 19 años. El Quiste Odontogénico Calcificante (QOC) fue descrito por primera vez cómo una entidad patológica por Gorlin y col. en 1962 [...] . Se trata de un tumor benigno odontogénico mixto,y aunque la mayoria de estas lesiones presentan características quísticas en algunos casos se presenta como una masa sólida (15 %), y su transformación maligna está bien documentada. El QOC se presenta en ocasiones asociado a otros tumores odontogénicos, el más común es el odontoma al que aparece relacionado en el 24% de los casos. Para esta asociación se ha sugerido el término de "Quiste Odontogénico Odontocalcificante". Radiológicamente es una lesión mixta, bien definida y que histológicamente consiste en un gran quiste en cuya parte central existe un área sólida con acúmulos de esmalte y dentina distribuidos irregularmente en algunas zonas y en otros lugares adopta un aspecto organoide bien definido. Se efectúa una revisión de la literatura y se discute su patogénesis. Abstract in english We report a calcifying odontogenic cyst associated with odontoma (COCaO) and an included permanent canine in the superior maxilla, in a 19 year-old-man. The calcifying odontogenic cyst (COC) was first described as a distinct entity by Gorlin et al in 1962. The lesion is a mixed odontogenic benign tu [...] mor, and although most of the cases present cystic characteristics, a few are of the solid type (15%), and its rare malignant transformation is well documented. The COC may occur in association with other odontogenic tumors, the most common is the odontoma, occurring in about 24% of the cases. For this association the term Odontocalcifying odontogenic cyst has been suggested. Radiographically is a well defined mixed lesion and histologically consists of a large cyst. In the central area of the cyst enamel and dentin deposits can be found, irregularly distributed in areas and in other parts it takes on a well defined organoid aspect. A thorough review of literature takes place and the pathogenesis is discussed.

  13. Quiste gigante de la glándula de Bartolino: reporte de caso y revisión de la literatura A case report and literature review regarding giant Bartholin gland cyst

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    ??dgar E Rivas-Perdomo

    2010-12-01

    Full Text Available Introducción: en el presente artículo se expone el caso de una paciente que tuvo un quiste gigante de la glándula de Bartolino, el cual alcanzó un diámetro de 10 cm. La paciente presentó algunas dificultades diagnósticas y terapéuticas por lo que fue necesaria la escisión de la glándula y la posterior reconstrucción de la vulva. El diagnóstico definitivo fue establecido por anatomía patológica. El caso se presenta con el objetivo de realizar una revisión de la literatura respecto al tratamiento. Materiales y métodos: se realizó una búsqueda de la literatura relacionada con el tema en las bases de datos electrónicas PubMed, SciELO, ScienceDirect y MD Consult, utilizando las palabras clave: "glándulas de Bartolino", "quistes" y "marsupialización". Además, se revisaron referencias de libros de textos. Conclusiones: la urgencia en el tratamiento depende de los síntomas de la paciente. Un quiste asintomático podría no requerir tratamiento. Sin embargo, la no mejoría dentro de las primeras 72 horas o la evolución hacia una forma de absceso requerirá un tratamiento quirúrgico de emergencia. Se ha descrito una amplia variedad de tratamientos que incluyen una serie de procedimientos quirúrgicos tales como: 1 incisión simple y drenaje, 2 fistulización o marsupialización, 3 colocación de un catéter de Word, 4 escleroterapia con alcohol, 5 aplicación de nitrato de plata y 6 ablación del quiste utilizando dióxido de carbono (CO2 con láser.Introduction: the case of a patient who had a giant Bartholin gland cyst is presented; it reached 10 cm diameter, presenting some diagnostic and therapeutic difficulties, requiring the excision of the gland and later reconstruction of the vulva. Definitive diagnosis was established by pathological anatomy. The case is presented as it led to a review of the pertinent literature regarding the relevant treatment. Materials and methods: a search was made of the pertinent literature in PubMed, SciELO, ScienceDirect and MD Consult databases, using the key words "Bartholin glands", "cysts", "marsupialization". Pertinent reference books were also reviewed. Conclusions: the urgency of treatment depends on a particular patient's treatment. An asymptomatic cyst may not require treatment; however, if there is no improvement within the first 72 hours or it evolves towards an abscess, then it will require emergency surgical treatment. A broad variety of treatments has been described which includes a series of surgical procedures, which include: simple incision and drainage, fistulization or marsupialization, placing a Word catheter, sclerotherapy with alcohol, applying silver nitrate and cyst ablation using carbon dioxide (CO2 laser.

  14. Quiste gigante de la glándula de Bartolino: reporte de caso y revisión de la literatura / A case report and literature review regarding giant Bartholin gland cyst

    Scientific Electronic Library Online (English)

    Édgar E, Rivas-Perdomo.

    2010-12-01

    Full Text Available Introducción: en el presente artículo se expone el caso de una paciente que tuvo un quiste gigante de la glándula de Bartolino, el cual alcanzó un diámetro de 10 cm. La paciente presentó algunas dificultades diagnósticas y terapéuticas por lo que fue necesaria la escisión de la glándula y la posteri [...] or reconstrucción de la vulva. El diagnóstico definitivo fue establecido por anatomía patológica. El caso se presenta con el objetivo de realizar una revisión de la literatura respecto al tratamiento. Materiales y métodos: se realizó una búsqueda de la literatura relacionada con el tema en las bases de datos electrónicas PubMed, SciELO, ScienceDirect y MD Consult, utilizando las palabras clave: "glándulas de Bartolino", "quistes" y "marsupialización". Además, se revisaron referencias de libros de textos. Conclusiones: la urgencia en el tratamiento depende de los síntomas de la paciente. Un quiste asintomático podría no requerir tratamiento. Sin embargo, la no mejoría dentro de las primeras 72 horas o la evolución hacia una forma de absceso requerirá un tratamiento quirúrgico de emergencia. Se ha descrito una amplia variedad de tratamientos que incluyen una serie de procedimientos quirúrgicos tales como: 1) incisión simple y drenaje, 2) fistulización o marsupialización, 3) colocación de un catéter de Word, 4) escleroterapia con alcohol, 5) aplicación de nitrato de plata y 6) ablación del quiste utilizando dióxido de carbono (CO2 ) con láser. Abstract in english Introduction: the case of a patient who had a giant Bartholin gland cyst is presented; it reached 10 cm diameter, presenting some diagnostic and therapeutic difficulties, requiring the excision of the gland and later reconstruction of the vulva. Definitive diagnosis was established by pathological a [...] natomy. The case is presented as it led to a review of the pertinent literature regarding the relevant treatment. Materials and methods: a search was made of the pertinent literature in PubMed, SciELO, ScienceDirect and MD Consult databases, using the key words "Bartholin glands", "cysts", "marsupialization". Pertinent reference books were also reviewed. Conclusions: the urgency of treatment depends on a particular patient's treatment. An asymptomatic cyst may not require treatment; however, if there is no improvement within the first 72 hours or it evolves towards an abscess, then it will require emergency surgical treatment. A broad variety of treatments has been described which includes a series of surgical procedures, which include: simple incision and drainage, fistulization or marsupialization, placing a Word catheter, sclerotherapy with alcohol, applying silver nitrate and cyst ablation using carbon dioxide (CO2) laser.

  15. Surgical reduction in a delayed case of traumatic testicular dislocation.

    Science.gov (United States)

    Phuwapraisirisan, Samart; Lim, Meechai; Suwanthanma, Weerapat

    2010-11-01

    A 27-year-old Thai male was admitted with left groin pain and he felt that he lost his left testis three weeks after his motorcycle accident-car collision. He had not been diagnosed after four days of admission at the previous hospital. Surgical reduction was performed without acute and delayed complications after three months of follow-up. Traumatic testicular dislocation is an uncommon sequel of trauma usually related to straddle injury from motorcycle accidents. Diagnosis depends on the awareness of the physician of its possibility of occurrence. Physical examination is the most helpful in diagnosis. CT scan or Doppler ultrasound, if available, may be helpful in diagnosis, particularly locating the extrascrotal testicle and detecting testicular viability. Manual reduction is the treatment of choice for acute traumatic dislocation of testis. Open reduction is indicated for the delayed case, or if there are (1) difficulty in determining the integrity of dislocated testis, (2) possibility of torsion, (3) failure of close reduction, or (4) the minimal morbidity of an inguinal exploration. PMID:21114212

  16. Testicular and spermatozoan parameters in the pukeko (Porphyrio porphyrio melanotus).

    Science.gov (United States)

    Gunn, M R; Champion, Z; Casey, M E; Teal, P; Casey, P J

    2008-12-01

    The pukeko (Porphyrio porphyrio melanotus) is widespread in New Zealand, and is the closest living relative to the endangered takahe (Porphyrio mantelli), which has a relatively high rate of infertility. In this study, sperm collected from a number of pukeko was analysed in order to model the reproductive physiology of the male takahe. In addition, testicular parameters were measured. To ascertain the best method of sperm collection five techniques for harvesting sperm were used on two occasions during the breeding season. All five techniques resulted in the successful recovery of sperm. However, the float-out technique produced the best quality samples. Following collection, the morphometry of unstained sperm was assessed. Our findings suggest that pukeko sperm is non-motile in the male reproductive tract. We found the mean sperm head length in the pukeko is 16.9mum, but sperm head length varied significantly between birds. Testicular weight and length was significantly correlated with bird weight (PNew Zealand native birds. PMID:18162336

  17. Testicular function following irradiation of the human prepubertal testis

    International Nuclear Information System (INIS)

    Testicular function was studied in ten men, aged between 17 and 36 years, who had received irradiation for a nephroblastoma during childhood. The dose of scattered irradiation to the testes ranged from 268 to 983 rad. Eight subjects had either oligo-or azoosperma (0 to 5.6 million/ml), seven of whom had an elevated serum follicle stimulating hormone (FSH) level. One subject showed evidence of Leydig cell dysfunction with a raised serum luteinizing hormone level (LH) and a low plasma testosterone concentration. A second group of eight prepubertal males, aged between 8 and 14 years, were studied. These had also been irradiated for abdominal malignancies during childhood and received a similar dose of irradiation to the testis as the first group studied. The plasma testosterone levels were within the normal range in all eight. The mean gonadotropin levels were not significantly different from normal. Thus irradiation-induced damage to the germinal epithelium in prepubertal boys raised FSH levels after puberty but not before it. The conclusion is that inhibin has a minor role in the control of the pre-pubertal hypothalmic-pituitary testicular axis and its contribution to gonadal control of gonadotrophin secretion changes with sexual maturation. (author)

  18. Yolk sac tumor in a patient with transverse testicular ectopia

    Directory of Open Access Journals (Sweden)

    Zhu Yi-Ping

    2011-08-01

    Full Text Available Abstract Transverse testicular ectopia (TTE is a rare anomaly in which both testes descend through a single inguinal canal. We report a case of yolk sac tumor in the ectopic testis of a patient with TTE. A 24-year-old man presented to our hospital with a left inguinal-mass, right cryptorchidism and elevated alpha-fetoprotein (AFP. A left herniotomy 3 years earlier demonstrated both testes in the left scrotum, one above another positionally. Four months ago, a left scrotal mass appeared and radical orchiectomy of both testes revealed testicular yolk sac tumor of the ectopic testis. An enlarging left inguinal-mass appeared 2 months ago and he was referred to our hospital. Laboratory data showed an elevation of AFP (245.5 ng/ml and a 46 XY karyotype. He underwent bilateral retroperitoneal lymph node dissection and simultaneous left inguinal mass dissection. Histopathologic examination revealed a diagnosis of recurrent yolk sac tumor in the left inguinal mass. The retroperitoneal lymph node was not enlarged and, on histopathology, was not involved. The patient has now been followed up for 8 months without evidence of biochemical or radiological recurrence.

  19. Effect of oral administration of terephthalic acid on testicular functions of rats

    International Nuclear Information System (INIS)

    To investigate the toxic effect of terephthalic acid (TPA) on testicular functions of rats, male Sprague-Dawley rats were orally administered TPA in diet at the levels 0 (control), 0.2, 1 and 5% for 90 days. Testicular functions were assessed by histopathology, testicular sperm head counts, daily sperm production, sperm motility (measured by computer-assisted sperm analysis, CASA), biochemical indices (marker testicular enzymes), and serum testosterone. Oral feeding with terephthalic acid did not cause body and testes weight loss in TPA-treated groups. Histopathologically, damages of spermatogenic cells and Sertoli cells were observed by electron microscope, testicular sperm head counts, daily sperm production, and activities of sorbitol dehydrogenase (SDH) were decreased significantly in the 5% TPA group. The motility of spermatozoa was reduced significantly in all treated groups, which was correlated with administration doses. Serum testosterone concentrations were not declined in treated groups. In conclusion, TPA can cause impairment of testicular functions. The primary sites of action may be spermatogenic cells and Sertoli cells. The results of the present study provide first information of TPA on testicular functions in male rats

  20. Leydig cell function in boys following treatment for testicular relapse of acute lymphoblastic leukemia

    International Nuclear Information System (INIS)

    Current practice for achieving local control of testicular relapse in males with acute lymphoblastic leukemia (ALL) includes the use of 2,400-rad testicular radiation. Although this therapy is known to cause germ cell depletion, it has been assumed that it does not alter testicular secretion of testosterone. To test this assumption, the authors measured gonadotropin and testosterone levels in seven boys with ALL who had been treated with radiation for clinically apparent testicular relapse. In four of seven boys, testicular relapse was bilateral with overt involvement of one testicle and microscopic involvement of the other. Three of these four boys demonstrated delayed sexual maturation, and in addition to elevated follicle-stimulating hormone (FSH) concentrations, testosterone levels were low and luteinizing hormone levels were elevated compared with controls. These data indicate that boys with overt testicular leukemia who are treated with 2,400-rad testicular radiation are at risk for Leydig cell dysfunction. However, the relative contributions of radiation, prior chemotherapy, and leukemic infiltration to this dysfunction remain to be clarified

  1. Testicular shape and andrological aspects of young Nellore bulls under extensive farming

    Scientific Electronic Library Online (English)

    Jeanne Broch, Siqueira; Eunice, Oba; Rogério Oliveira, Pinho; Simone Eliza Facioni, Guimarães; Tamires, Miranda Neto; José Domingos, Guimarães.

    2012-03-01

    Full Text Available Aiming to determine the relationship between the frequency of testicular shape and the andrological aspects in young Nellore bulls, 18,676 animals were assessed. All andrological examinations were performed between the years 2000 and 2008. Animals were classified as able for breeding, able for breed [...] ing in natural mating system, unable for breeding and discarded. The testicular shape was classified as long, fairly long, oval-long, spherical-oval, and spherical. The analysis of Pearson correlations was performed for testicular shape with scrotal circumference, testicular volume, progressive motility, sperm vigor, major defects, minor defects and total defects. Testicles with oval shape prevailed (99.61%). It was obseved that 76.34; 66.34; 64.34; 58.33 and 50.00% of the animals were classified as sound for breeding for shapes long, fairly long, oval-long, spherical-oval, and spherical, respectively. Correlations between testicular shape with scrotal circumference, testicular volume, progressive motility, sperm vigor, major, minor and total defects were 0.26; 0.08; 0.00; 0.11; -0.02; 0.02 and -0.01, respectively. Testicular shape had no influence upon the andrological examination results. Testicles of long shape were prevalent within the population.

  2. Applied anatomic study of testicular veins in adult cadavers and in human fetuses

    Directory of Open Access Journals (Sweden)

    Luciano A. Favorito

    2007-04-01

    Full Text Available OBJECTIVES: Analyze the anatomic variations of the testicular veins in human cadavers and fetuses. MATERIALS AND METHODS: One hundred male adult cadavers and 24 fetuses were studied. Four anatomic aspects were considered: 1 Number of testicular veins, 2 The local of vein termination, 3 Type and number of collaterals present and 4 Testicular vein termination angle. RESULTS: Cadavers - Right side - One testicular vein occurred in 85% and 2 veins in 5% of the cases. There were communicating veins with the colon in 21% of the cases. Left side - One testicular vein occurred in 82%, two veins in 15%, three veins in 2% and four veins in 1% of the cases. There were communicating veins with the colon in 31% of the cases. Fetuses - Right side -One testicular vein occurred in all cases. This vein drained to the vena cava in 83.3% of the cases, to the junction of the vena cava with the renal vein in 12.5% and to the renal vein in 4.2%. There were communicating veins with the colon in 25% of the cases. Left side - One testicular vein occurred in 66.6% of the cases, and 2 veins in occurred 33.3%. Communicating veins with the colon were found in 41.6% of the cases. CONCLUSION: The testicular vein presents numeric variations and also variations in its local of termination. In approximately 30% of the cases, there are collaterals that communicate the testicular vein with retroperitoneal veins. These anatomic findings can help understanding the origin of varicocele and its recurrence after surgical interventions.

  3. Applied anatomic study of testicular veins in adult cadavers and in human fetuses

    Scientific Electronic Library Online (English)

    Luciano A., Favorito; Waldemar S., Costa; Francisco J.B., Sampaio.

    2007-04-01

    Full Text Available OBJECTIVES: Analyze the anatomic variations of the testicular veins in human cadavers and fetuses. MATERIALS AND METHODS: One hundred male adult cadavers and 24 fetuses were studied. Four anatomic aspects were considered: 1) Number of testicular veins, 2) The local of vein termination, 3) Type and n [...] umber of collaterals present and 4) Testicular vein termination angle. RESULTS: Cadavers - Right side - One testicular vein occurred in 85% and 2 veins in 5% of the cases. There were communicating veins with the colon in 21% of the cases. Left side - One testicular vein occurred in 82%, two veins in 15%, three veins in 2% and four veins in 1% of the cases. There were communicating veins with the colon in 31% of the cases. Fetuses - Right side -One testicular vein occurred in all cases. This vein drained to the vena cava in 83.3% of the cases, to the junction of the vena cava with the renal vein in 12.5% and to the renal vein in 4.2%. There were communicating veins with the colon in 25% of the cases. Left side - One testicular vein occurred in 66.6% of the cases, and 2 veins in occurred 33.3%. Communicating veins with the colon were found in 41.6% of the cases. CONCLUSION: The testicular vein presents numeric variations and also variations in its local of termination. In approximately 30% of the cases, there are collaterals that communicate the testicular vein with retroperitoneal veins. These anatomic findings can help understanding the origin of varicocele and its recurrence after surgical interventions.

  4. Efficacy of Liposomal Monensin on the Enhancement of the Antitumour Activity of Liposomal Ricin in Human Epidermoid Carcinoma (KB Cells

    Directory of Open Access Journals (Sweden)

    N Tyagi

    2013-01-01

    Full Text Available The monensin, known to enhance the cytotoxicity of ricin and ricin-based immunotoxins is a very hydrophobic molecule and this limits its administration in optimum doses under in vivo conditions. In order to realise its full potential, monensin was intercalated into various liposomal formulations and its ability to potentiate the cytotoxicity of ricin liposomes in human epidermoid carcinoma (KB cells was studied. It was observed that ricin cytotoxicity enhancing ability of monensin liposome depends on the surface charge as well as density and chain length of distearoyl phosphatidylethanolamine-methoxy polyethylene glycol present on the surface of liposomal monensin. Maximum potentiation on the cytotoxicity of liposomal ricin was observed by monensin entrapped in neutral liposome (106.5 fold followed by negatively charged (94.2 fold and positively charged liposome (90 fold. Studies on the effect of variation of density and chain length of distearoyl phosphatidylethanolamine-methoxy polyethylene glycol showed that neutral monensin liposomes having 2.5 mol% distearoyl phosphatidylethanolamine-methoxy polyethylene glycol with chain length of 2000 exhibits maximum potentiation (117.6 fold on the cytotoxicity of ricin liposomes when the cellular uptake of monensin liposome was maximum (42.0% and the zeta potential value on the surface of liposomes was ?0.645. The present study has clearly shown that liposomal monensin is very effective in enhancing the cytotoxicity of liposomal ricin in human cancer cells and liposome can be used as in vivo deliver vehicle for monensin to potentiate the cytotoxicity of liposomal ricin to eliminate cancer cells.

  5. Quiste branquial tipo I: presentación de un caso / A type-I brachial cyst: a case report

    Scientific Electronic Library Online (English)

    Fidel, Castro Pérez; Raúl, Rodríguez González; Juan M, Flores Contreras; Vivian, Álvarez Díaz; María de las Nieves, Cordero Ledesma.

    2010-12-01

    Full Text Available Se presenta el caso de una adolescente de 14 años de edad, raza blanca, del sexo femenino, con antecedentes de salud relativa, que se valoró en la consulta externa del Policlínico Universitario Ernesto Guevara de la Serna de Sandino, Pinar del Río, Cuba. La paciente presentó un cuadro caracterizado [...] por el aumento de volumen superficial de la región lateral derecha superior del cuello, por debajo de la rama horizontal de la mandíbula y por delante del borde anterior del músculo esternocleidomastoideo, cerca del pabellón auricular y la parótida, de aproximadamente 4 cm. de diámetro, móvil, no doloroso, de superficie lisa y consistencia renitente, sin cambios en la coloración de la piel; al examen físico otorrinolaringológico no se encontraron otras alteraciones, posteriormente se realizó un ultrasonido en esa región. El diagnóstico dio como resultado un quiste branquial y se procedió a la exéresis quirúrgica por el equipo de autores del artículo, realizándose estudio anatomopatológico. Los autores presentan las experiencias derivadas de la atención del caso, y revisan la literatura médica sobre el tema con especial referencia al diagnóstico y tratamiento. Abstract in english A Caucasian 14 year-old female adolescent having relative health history was assessed at "Ernesto Guevara de la Serna" Outpatient Clinic in Sandino, Pinar del Rio, Cuba. The patient presented a clinical chart which was characterized by an increase of the superficial volume of the right upper lateral [...] region of neck, below the horizontal branch of the mandible and to the front of the anterior border of sternocleidomastoid muscle, near outer ear and parotid having approximately 4cm of diameter, motile, painless, smooth surface and renitent consistency, without changes in skin color; physical and ENT examinations found no other alterations, subsequently a sonographic study in that region confirmed a brachial cyst that was surgically removed performing pathological studies. The authors presented the experiences derived from this case and the medical literature about the topic was reviewed emphasizing on the diagnosis and treatment.

  6. Quiste branquial tipo I: presentación de un caso A type-I brachial cyst: a case report

    Directory of Open Access Journals (Sweden)

    Fidel Castro Pérez

    2010-12-01

    Full Text Available Se presenta el caso de una adolescente de 14 años de edad, raza blanca, del sexo femenino, con antecedentes de salud relativa, que se valoró en la consulta externa del Policlínico Universitario Ernesto Guevara de la Serna de Sandino, Pinar del Río, Cuba. La paciente presentó un cuadro caracterizado por el aumento de volumen superficial de la región lateral derecha superior del cuello, por debajo de la rama horizontal de la mandíbula y por delante del borde anterior del músculo esternocleidomastoideo, cerca del pabellón auricular y la parótida, de aproximadamente 4 cm. de diámetro, móvil, no doloroso, de superficie lisa y consistencia renitente, sin cambios en la coloración de la piel; al examen físico otorrinolaringológico no se encontraron otras alteraciones, posteriormente se realizó un ultrasonido en esa región. El diagnóstico dio como resultado un quiste branquial y se procedió a la exéresis quirúrgica por el equipo de autores del artículo, realizándose estudio anatomopatológico. Los autores presentan las experiencias derivadas de la atención del caso, y revisan la literatura médica sobre el tema con especial referencia al diagnóstico y tratamiento.A Caucasian 14 year-old female adolescent having relative health history was assessed at "Ernesto Guevara de la Serna" Outpatient Clinic in Sandino, Pinar del Rio, Cuba. The patient presented a clinical chart which was characterized by an increase of the superficial volume of the right upper lateral region of neck, below the horizontal branch of the mandible and to the front of the anterior border of sternocleidomastoid muscle, near outer ear and parotid having approximately 4cm of diameter, motile, painless, smooth surface and renitent consistency, without changes in skin color; physical and ENT examinations found no other alterations, subsequently a sonographic study in that region confirmed a brachial cyst that was surgically removed performing pathological studies. The authors presented the experiences derived from this case and the medical literature about the topic was reviewed emphasizing on the diagnosis and treatment.

  7. Percutaneous Revision of a Testicular Prosthesis is Safe, Cost-effective, and Provides Good Patient Satisfaction

    Directory of Open Access Journals (Sweden)

    Eugene B. Cone

    2015-09-01

    Full Text Available Office-based percutaneous revision of a testicular prosthesis has never been reported. A patient received a testicular prosthesis but was dissatisfied with the firmness of the implant. In an office setting, the prosthesis was inflated with additional fluid via a percutaneous approach. Evaluated outcomes included patient satisfaction, prosthesis size, recovery time, and cost savings. The patient was satisfied, with no infection, leak, or complication after more than 1 year of follow-up, at significantly less cost than revision surgery. Percutaneous adjustment of testicular prosthesis fill-volume can be safe, inexpensive, and result in good patient satisfaction.

  8. A Korean boy with 46,XX testicular disorder of sex development caused by SOX9 duplication

    OpenAIRE

    Lee, Gyung Min; KO, JUNG MIN; Shin, Choong Ho; Yang, Sei Won

    2014-01-01

    The 46,XX testicular disorder of sex development (DSD), also known as 46,XX male syndrome, is a rare form of DSD and clinical phenotype shows complete sex reversal from female to male. The sex-determining region Y (SRY) gene can be identified in most 46,XX testicular DSD patients; however, approximately 20% of patients with 46,XX testicular DSD are SRY-negative. The SRY-box 9 (SOX9) gene has several important functions during testis development and differentiation in males, and overexpression...

  9. Ruptured Retroperitoneal Node Presenting as Hemoperitoneum-An Unusual Presentation of testicular tumour.

    Science.gov (United States)

    Chandrasekhar, Senthil Kumar Azhisoor; Kathiresan, Narayanaswamy

    2014-09-01

    Herewith we are reporting an unusual presentation of testicular tumour. The patient is a 37 years old gentleman diagnosed with Stage III seminoma post orchidectomy on chemotherapy and had spontaneous rupture of retroperitoneal nodal mass and presented with hemoperitoneum and hypovolemic shock. He was successfully salvaged by aggressive resuscitation, emergency laparotomy and resection of ruptured nodal mass and is presently disease free. This article is aimed at highlighting this unusual presentation and complication of advanced testicular tumour and the need for aggressive surgery even in the so called hopeless situations. The need for multidisciplinary care in the cure of advanced testicular care is once again reemphasized. PMID:25419079

  10. Características biométricas testiculares para avaliação de touros zebuínos da raça Nelore / Testicular biometrics characteristics to evaluate the Nellore zebu breed bulls

    Scientific Electronic Library Online (English)

    Maria Marina, Unanian; Antonio Emidio Dias Feliciano, Silva; Concepta, McManus; Eduardo Penteado, Cardoso.

    2000-02-01

    Full Text Available RESUMO - O objetivo deste estudo foi analisar as características de volume e forma testicular em zebuínos jovens da raça Nelore para caracterizar a sua importância na avaliação e seleção de reprodutores. Foram examinados a circunferência escrotal (CE), o comprimento (COMP), a largura (LARG) e o volu [...] me testicular (VOL) em 442 machos aos 12 e 18 meses de idade, divididos em dois grupos contemporâneos (G1 e G2), em função da data do nascimento. O VOL foi calculado pela fórmula: VOL = 2[(r²) x pi x h] em que r = LARG/2, h = COMP, e pi = 3,14. Os valores médios de CE, COMP, LARG e VOL, aos 12 meses de idade, foram 184,89±15,79 mm, 65,96±6,48 mm, 32,58±4,63 mm e 113,80±42,03 cm³, e aos 18 meses, 236,81±mm, 79,31±11,16 mm, 42,92±5,83 mm e 239,26±90,56 cm³, respectivamente. Os parâmetros, aos 12 e 18 meses de idade, variaram em função dos grupos contemporâneos, sendo altamente correlacionados. A forma dos testículos foi avaliada pela razão LARG/COMP, resultando em cinco formas: longa (razão 0,875). Em 87% dos animais, os testículos apresentaram forma longa e, em 74%, houve mudança da forma testicular com a idade. Os parâmetros estudados variaram em função da forma testicular, e o crescimento dos testículos ocorreu em largura. Os resultados sugerem que, ao selecionar reprodutores, principalmente jovens, deve-se considerar o volume testicular, além de possíveis mudanças da forma testicular. Abstract in english ABSTRACT - The objective of this study was to analyze the testicular volume and shape in young males of Nellore Zebu breed and their importance for the evaluation and selection of sires. Four hundred and forty two males, from 12 to 18 month of age, were examined for scrotal circumference (CE), lengt [...] h (COMP), width (LARG) and testicular volume (VOL). The animals were divided in two groups (G1 and G2) according to their date of birth. The VOL was calculated by the formula: VOL = 2[(r²) x pi x h], where r, h and pi are LARG/2, length and 3.14, respectively. The mean values of CE, COMP, LARG and VOL at 12 month of age were 184.89±15.79 mm, 65.96±6.48 mm, 2.58±4.63 mm and 113.80±42.03 cm³, and at 18 months of age were 236.81±mm, 79.31±11.16 mm, 42.92±5.83 mm and 239.26±90.56 cm³, respectively. The parameters at 12 and 18 months of age were influenced by contemporary groups, being highly correlated. The testicular shape was considered as a length to width ratio, being recorded five forms: long (ratio .875 ratio). 87% of the animals presented the long shape and, in 74%, the testicular shape changed with the age. All the parameters were influenced by testicular shape, and the testis grew in width. The results suggest that the selection of young bulls should consider the testicular volume besides the possible change in the testicular shape.

  11. Quiste conjuntival de inclusión tras cirugía de estrabismo según técnica de retroinserción en asa / Conjunctival inclusion cyst after strabismus surgery by hang-back recession

    Scientific Electronic Library Online (English)

    M.I., Pérez-Flores; J.A., Ortiz-Rey; I., Antón-Badiola; J., Lorenzo-Carrero.

    2006-11-01

    Full Text Available Caso clínico: Mujer de 24 años con antecedentes de endotropía congénita más DVD operada en la infancia. Se realiza intervención quirúrgica y cuatro meses tras la cirugía presenta una lesión quística que recidiva tras drenaje y tratamiento médico. Se realiza exéresis completa de la lesión. Discusión: [...] El origen de los quistes de inclusión conjuntivales tras cirugía de estrabismo sería la implantación escleral de células epiteliales. Sugerimos la relación con la sutura escleral como mecanismo de formación, independientemente de la posición del músculo. El tratamiento de elección en los quistes de gran tamaño es la resección completa. Abstract in english Case report: A 24-year-old woman, with a history of infantile esotropia and DVD operated on in infancy, had strabismus surgery performed by us. Four months later she presented with a cystic lesion that recurred after drainage and medical treatment. Complete excision of the cystic lesion was therefor [...] e performed. Discussion: The epithelial cells implanted on the sclera at the time of the most recent surgery may have been the origin of inclusion cyst which developed after the strabismus surgery. This suggests a possible relationship with the scleral suture as the mechanism of cyst formation, independent of the muscle position. Complete excision is the recommended treatment for large cysts.

  12. Quiste dentígero asociado con mesiodens: Exposición de un caso, revisión de la literatura y diagnóstico diferencial Dentigerous cyst associated with mesiodens: a case report, literature review and differential diagnostic

    Directory of Open Access Journals (Sweden)

    F.J. Rodríguez Romero

    2011-12-01

    Full Text Available El quiste dentígero es uno de los quistes odontogénicos más frecuentes y están asociados con la corona de un diente no erupcionado o en desarrollo. Cuando se asocian con dientes supernumerarios son poco frecuentes y constituyen el 5-6% de todos los quistes dentígeros. En región maxilar, el 90% de los casos se asocian a mesiodens. El objetivo de este artículo es exponer el caso de una adolescente de 14 años con un quiste dentígero asociado con un diente supernumerario (mesiodens impactado en región maxilar anterior, su manejo dental y revisión de la literatura.Dentigerous cyst is one of the most prevalent types of odontogenic cyst and is associated with crown of an unerupted or developing tooth. Dentigerous cysts associated with supernumerary teeth are rare and estimated to constitute 5-6% of all dentigerous cysts. The vast majority, about 90%, are associated with a maxillary mesiodens. The purpose of this article to report the case of an 14-year-old a teenager with a dentigerous cyst associated with an impacted anterior maxillary supernumerary tooth, its dental management and literature review.

  13. Quiste dentígero asociado con mesiodens: Exposición de un caso, revisión de la literatura y diagnóstico diferencial / Dentigerous cyst associated with mesiodens: a case report, literature review and differential diagnostic

    Scientific Electronic Library Online (English)

    F.J., Rodríguez Romero; S., Cerviño Ferradanes; P., Muriel Cueto.

    2011-12-01

    Full Text Available El quiste dentígero es uno de los quistes odontogénicos más frecuentes y están asociados con la corona de un diente no erupcionado o en desarrollo. Cuando se asocian con dientes supernumerarios son poco frecuentes y constituyen el 5-6% de todos los quistes dentígeros. En región maxilar, el 90% de lo [...] s casos se asocian a mesiodens. El objetivo de este artículo es exponer el caso de una adolescente de 14 años con un quiste dentígero asociado con un diente supernumerario (mesiodens) impactado en región maxilar anterior, su manejo dental y revisión de la literatura. Abstract in english Dentigerous cyst is one of the most prevalent types of odontogenic cyst and is associated with crown of an unerupted or developing tooth. Dentigerous cysts associated with supernumerary teeth are rare and estimated to constitute 5-6% of all dentigerous cysts. The vast majority, about 90%, are associ [...] ated with a maxillary mesiodens. The purpose of this article to report the case of an 14-year-old a teenager with a dentigerous cyst associated with an impacted anterior maxillary supernumerary tooth, its dental management and literature review.

  14. Enucleación de quiste periapical simultáneo a la obturación del sistema de conductos radiculares / Periapical cyst enucleation and simultaneous sealing of the root canal system

    Scientific Electronic Library Online (English)

    Lida, Velazque; Alexandre, Simões-Nogueira; Ilan, Sampaio do Vale; Victor, Tiegui Neto; Andrea, Guedes Barreto Gonçales; Eduardo, Sánches Gonçales.

    2014-06-01

    Full Text Available Introducción: los quistes periapicales representan el tipo más frecuente dentro de los quistes odontogénicos. Su origen está relacionado con una necrosis pulpar y un consecuente estímulo de los restos epiteliales del ligamento periodontal (Malassez). Objetivo: describir un caso clínico de enucleació [...] n de quiste periapical simultáneo a la obturación del sistema de conductos radiculares. Presentación del caso: paciente de sexo femenino, 67 años de edad, sin alteraciones sistémicas; buscó atención odontológica por presentar dolor dental y acúmulo de alimentos en la región de molares inferiores del lado izquierdo. Al examen clínico se observó caries extensa en el segundo molar inferior izquierdo con compromiso de furca, ausencia de aumento de volumen vestibular, sin fistula; en la radiografía periapical se evidenció lesión cariosa extensa recidivante en el segundo molar inferior izquierdo, y primer molar inferior izquierdo con tratamiento endodóntico y presencia de área radiolúcida de contornos bien definidos en la región periapical compatible con quiste periapical. El tratamiento estuvo a cargo de un equipo multidisciplinario por lo que se decidió realizar exodoncia del segundo molar inferior izquierdo y cirugía paraendodóntica con enucleación quirúrgica simultánea a la obturación del sistema de conductos radiculares primer molar inferior izquierdo; el examen histopatológico de la muestra extraída comprobó tratarse de un quiste periapical. Se realizó seguimiento radiográfico dos años después y mostró un completo reparo óseo del área afectada. Conclusiones: se concluye que el tratamiento descrito constituye una alternativa válida para la resolución de casos donde la endodoncia convencional es limitada para mantener la función y estética de una pieza dentaria. Abstract in english Introduction: periapical cysts are the most common odontogenic cysts. Their origin is related to pulp necrosis and the consequent stimulation of epithelial rests of the periodontal ligament (Malassez). Objective: describe a clinical case of periapical cyst enucleation and simultaneous sealing of the [...] root canal system. Case report: a female 67-year-old patient without any systemic alteration sought care for dental pain and accumulation of food in the area of the lower left molars. Clinical examination revealed extensive decay in the lower left second molar with furcation involvement and absence of vestibular volume increase without a fistula. Periapical radiography showed an extensive recurrent carious lesion in the lower left second molar and lower left first molar with endodontic treatment and presence of a radiolucent area of a sharp outline in the periapical region compatible with periapical cyst. Treatment was conducted by a multidisciplinary team, who decided to perform extraction of the lower left second molar and paraendodontic surgery with surgical enucleation and simultaneous sealing of the root canal system in the lower left first molar. Histopathological examination of the specimen removed revealed it was a periapical cyst. Radiographic follow-up conducted two years later showed complete bone repair in the affected area. Conclusions: it is concluded that the treatment described is a valid alternative for the resolution of cases in which conventional endodontics is insufficient to preserve the function and aesthetic appearance of a tooth.

  15. Testis-sparing surgery in the benign testicular tumors in boys

    International Nuclear Information System (INIS)

    Background. Testicular neoplasm in boys are rare. In despite of the adult testicular, neoplasm in children non-seminoma germ cell tumors are seen much more frequent, also in 30-70% of cases benign lesions exist and those tumors do not require chemo- and radiotherapy. Recently there is a great enthusiasm for testis sparing surgery. Objectives. Authors would like to present six boys with testicular mass operated with testis sparing surgery for benign tumors. Material and Methods. Between 1995 and 2004 in Department of Pediatric Surgery and Urology 33 boys were operated because of testicular malignances. In six cases in age from 1 to 17 years after histological (interoperation) confirmation of the benign origin of the tumor testis sparing surgery were performed. Results. In all six operated boys follow up is from 2 to 5 year and all are free from disease's symptoms. Ultrasound view of the operated testes are normal. (authors)

  16. Cervical mature teratoma 17 years after initial treatment of testicular teratocarcinoma: report of a late relapse

    Directory of Open Access Journals (Sweden)

    Alavion Mina

    2007-01-01

    Full Text Available Abstract Background Late relapses of testicular germ cell tumor are uncommon. We report a case of cervical mature teratoma appeared 17 years after treatment of testicular teratocarcinoma. Case presentation A 20- year- old patient underwent left sided orchiectomy followed by systemic therapy and retroperitoneal residual mass resection in 1989. He remained in complete remission for 200 months. In 2005 a huge left supraclavicular neck mass with extension to anterior mediastinum appeared. Radical surgical resection of the mass was performed and pathologic examination revealed mature teratoma. Conclusion This is one of the longest long-term reported intervals of a mature teratoma after treatment of a testicular nonseminoma germ cell tumor. This case emphasizes the necessity for follow up of testicular cancer throughout the patient's life.

  17. Therapy of endocrine disease : Testicular function and fertility in men with Klinefelter syndrome: a review

    DEFF Research Database (Denmark)

    Aksglæde, Lise; Juul, A

    2013-01-01

    Klinefelter syndrome, 47,XXY (KS), is the most frequent sex chromosome aberration in males, affecting 1 in 660 newborn boys. The syndrome is characterized by testicular destruction with extensive fibrosis and hyalinization of the seminiferous tubules resulting in small testes, hypergonadotropic hypogonadism, and azoospermia in the majority of cases. Until recently, infertility was considered an untreatable condition in KS. However, with the development of new advanced assisted reproductive techniques such as testicular sperm extraction (TESE) combined with ICSI it seems that KS patients should no longer be labelled as infertile. Especially, microdissection (micro)-TESE has proved to be an advantageous procedure for the identification of testicular spermatozoa in KS. The aim of this review was to describe current knowledge on the testicular changes occurring in KS, the associated changes in reproductive hormones and spermatogenesis, and the existing possibilities of biological fatherhood in 47,XXY patients.

  18. Variability of venous anatomy of rat testis: application to experimental testicular surgery.

    Science.gov (United States)

    Pascual, J A; Lemmi, C; Rajfer, J

    1992-01-01

    The venous drainage of the testis of the laboratory rat was observed in 31 animals. The right testicular (internal spermatic) vein drained directly into the right common iliac vein in 77.4%, and into the inferior vena cava in 22.6% of the animals. The left testicular vein drained into the left common iliac vein in all animals, but in 90.3% there was also an accessory branch of the testicular vein draining into the left renal vein. These observations suggest that in the rat the exact anatomy of the venous drainage of each testis should be identified prior to undertaking any surgical procedure on the testis where the venous vasculature plays a major role such as testicular transplantation or the creation of an experimental varicocele. PMID:1453936

  19. Involvement of epigenetic modifiers in the pathogenesis of testicular dysgenesis and germ cell cancer

    DEFF Research Database (Denmark)

    Lawaetz, Andreas C; Almstrup, Kristian

    2015-01-01

    Testicular germ cell cancer manifests mainly in young adults as a seminoma or non-seminoma. The solid tumors are preceded by the presence of a non-invasive precursor cell, the carcinoma in situ cell (CIS), which shows great similarity to fetal germ cells. It is therefore hypothesized that the CIS cell is a fetal germ cell that has been arrested during development due to testicular dysgenesis. CIS cells retain a fetal and open chromatin structure, and recently several epigenetic modifiers have been suggested to be involved in testicular dysgenesis in mice. We here review the possible involvement of epigenetic modifiers with a focus on jumonji C enzymes in the development of testicular dysgenesis and germ cell cancer in men.

  20. Identification of a testicular odorant receptor mediating human sperm chemotaxis.

    Science.gov (United States)

    Spehr, Marc; Gisselmann, Gunter; Poplawski, Alexandra; Riffell, Jeffrey A; Wetzel, Christian H; Zimmer, Richard K; Hatt, Hanns

    2003-03-28

    Although it has been known for some time that olfactory receptors (ORs) reside in spermatozoa, the function of these ORs is unknown. Here, we identified, cloned, and functionally expressed a previously undescribed human testicular OR, hOR17-4. With the use of ratiofluorometric imaging, Ca2+ signals were induced by a small subset of applied chemical stimuli, establishing the molecular receptive fields for the recombinantly expressed receptor in human embryonic kidney (HEK) 293 cells and the native receptor in human spermatozoa. Bourgeonal was a powerful agonist for both recombinant and native receptor types, as well as a strong chemoattractant in subsequent behavioral bioassays. In contrast, undecanal was a potent OR antagonist to bourgeonal and related compounds. Taken together, these results indicate that hOR17-4 functions in human sperm chemotaxis and may be a critical component of the fertilization process. PMID:12663925

  1. Radionuclide ventriculography in testicular tumor patients following chemotherapy

    International Nuclear Information System (INIS)

    The toxicity was investigated of cytostatics with respect to the myocardium. Radionuclide ventriculography was used to monitor a group of 38 patients treated with cisplatin, adriamycin, vepeside, vinblastine and bleomycin for testicular carcinoma. The examination was performed prior to chemotherapy, in the course of chemotherapy and within two years after its termination. The global ejection fraction of the left ventricle, the diastolic and residual volumes, heart beat and the level of arrhythmia were examined. It was found that deviations from the normal condition appear from the start of therapy to two and more years after its termination and in a healthy heart may well be compensated. Radionuclide ventriculography may be recommended for patients prior to the start of chemotherapy. (M.D.). 7 figs

  2. Testicular germ cell tumors. Current concepts and management strategies.

    Science.gov (United States)

    Cost, N G

    2013-06-01

    Testicular germ cell tumors (T-GCTs) are the most common solid tumor in adolescent and young adult men. Due to the success of multidisciplinary management, the prognosis of all stages of T-GCT is quite good. The development of complimentary therapeutic strategies including modern cytotoxic chemotherapy regimens, appropriate utilization of radiotherapy, and timely surgical resection has made T-GCTs the model of a "curative" malignancy. Herein we review the background, epidemiology, and genetics of the disease, as well as an approach to its diagnosis and staging, including rationale for managing T-GCT in its various stages. In summary, while some areas in T-GCT care are debated, the vast majority of patients should be approached in a standardized manner which ensures optimal oncologic outcomes and minimal therapeutic morbidity. PMID:23703101

  3. "Mixed germ cell testicular tumor" in an adult female

    Directory of Open Access Journals (Sweden)

    Udasimath Shivakumarswamy

    2012-01-01

    Full Text Available The androgen insensitivity (testicular feminization syndrome was described by Morris in phenotypic females with 46XY karyotype, presenting with primary amenorrhea, adequate breast development, and absent or scanty pubic or axillary hair. Gonads consist usually of seminiferous tubules without spermatogenesis. These patients have a 5-10% risk of developing germ cell tumors, usually after the complete development of secondary female sexual characteristics. We hereby report a case considered as a female with married life of 15 years, who was operated for severe abdominal pain. Phenotype characters were that of female. Microscopic examination of the tumor from the abdomen revealed germinoma and yolk sac tumor with adjacent seminiferous tubules. Karyotyping showed 46XY. Final diagnosis of malignant mixed germ cell tumor in androgen insensitivity syndrome was made. Surveillance may be the most appropriate option when these conditions are initially diagnosed in adulthood to prevent development of germ cell tumors.

  4. Structural analysis of testicular appendices in patients with cryptorchidism

    Scientific Electronic Library Online (English)

    Guilherme D., Tostes; Suelen F., Costa; Joao P. de, Carvalho; Waldemar S., Costa; Francisco J.b., Sampaio; Luciano A., Favorito.

    2013-04-01

    Full Text Available Objectives Report the incidence and structure of testicular appendices (TAs) in patients with cryptorchidism, comparing their incidence with epididymal anomalies (EA) and patency of the vaginal process (PVP) and analyzes the structure of TAs. Material and Methods We studied 72 testes of patients [...] with cryptorchidism (average of 6 years), and 8 testes from patients with hydroceles (average of 9 years). We analyzed the relations among the testis, epididymis and PVP and prevalence and histology of the TAs. The appendices of 10 patients with cryptorchidism and 8 with hydrocele were dissected and embedded in paraffin and stained with Masson trichrome; Weigert and Picro-Sirius Red with polarization and immunohistochemistry analysis of the collagen type III fibers to observe collagen. The stereological analysis was done with the software Image Pro and Image J, using a grid to determine volumetric densities (Vv). Means were statistically compared using the ANOVA and unpaired T test (p

  5. Expanding access to testicular tissue cryopreservation: an analysis by analogy.

    Science.gov (United States)

    Ruutiainen, Tuua; Miller, Steve; Caplan, Arthur; Ginsberg, Jill P

    2013-01-01

    Researchers are developing a fertility preservation technique--testicular tissue cryopreservation (TTCP)--for prepubescent boys who may become infertile as a result of their cancer treatment. Although this technique is still in development, some researchers are calling for its widespread use. They argue that if boys do not bank their tissue now, they will be unable to benefit from any therapies that might be developed in the future. There are, however, risks involved with increasing access to an investigational procedure. This article examines four methods of expanding access to TTCP: (1) expansion of institutional review board (IRB)-approved research trials; (2) offering TTCP as an innovative procedure in hospitals; (3) offering TTCP as a standard practice in hospitals; and (4) commercialization of TTCP. The ethical and practical implications of each are evaluated through a comparison with umbilical cord blood banking (UCBB), a technology that has achieved widespread use based on similar claims of future benefit. PMID:23428034

  6. The development of cat testicular sperm cryopreservation protocols: Effects of tissue fragments or sperm cell suspension.

    Science.gov (United States)

    Chatdarong, Kaywalee; Thuwanut, Paweena; Morrell, Jane M

    2016-01-15

    In endangered animals that have been found dead or sterilized for medical reasons, testis is the ultimate source of haploid DNA or sperm. Thus, preservation of testicular sperm may be performed to rescue their genetics. The aim of this study was to evaluate protocols for testicular sperm freezing: as tissue fragments or cell suspension in domestic cats as a model. A pair of testes from each cat (n = 9) were cut into eight equal pieces. Four randomly selected pieces were cryopreserved as: (1) tissue pieces using two-step freezing; (2) tissue pieces using a slow passive cooling device (CoolCell); (3) sperm suspension after single-layer centrifugation (SLC) through colloids; and (4) sperm suspension without being processed through SLC. A testicular piece from each cat served as fresh control. Testicular sperm membrane and DNA integrity were evaluated before, and after, the cryopreservation process. In addition, spermatogenic cell types (testicular sperm, spermatogonia, spermatocyte, and spermatid) present in the suspension samples were counted before and after SLC. The results found that testicular sperm membrane integrity in the suspension after SLC process was higher than that in the fragment form neither using the two-step nor CoolCell freezing, both before and after freezing (before freezing: 92.3 ± 3.4 vs. 81 ± 4.5 and 80.0 ± 7.0; after freezing: 84.5 ± 4.6 vs. 71.2 ± 12 and 76.2 ± 4.6; P ? 0.05). Testicular sperm DNA integrity was, however, not different among groups. Furthermore, the samples processed through the SLC had higher ration of sperm cells: other spermatogenic cells than those were not processed through the SLC (88.9 ± 3.8 vs. 30 ± 7.9; P ? 0.05). In summary, testicular sperm cryopreserved as a minced suspension is considered suitable in terms of preventing sperm membrane integrity, and SLC is considered a selection tool for enriching haploid sperm cells from castrated or postmortem cats. PMID:26498389

  7. Testicular Self-Examination: Are Primary Care Physicians Teaching This Preventive Measure?

    OpenAIRE

    Diotallevi, Mark

    1989-01-01

    The author polled 118 family physicians about their screening procedures for testicular cancer in males at risk. Fewer physicians (63%) teach testicular self-examination (TSE) than teach breast self-examination (100%) as part of a periodic health examination. Physicians who examine their own testes or breasts regularly are more likely to examine their patients' testes during a periodic examination and to teach TSE to males at risk. Female physicians are more likely (75%) than male physicians ...

  8. Improved gene expression signature of testicular carcinoma in situ

    DEFF Research Database (Denmark)

    Almstrup, Kristian; Leffers, Henrik; Lothe, Ragnhild A; Skakkebaek, Niels E; Sonne, Si B; Nielsen, John E; Rajpert-De Meyts, Ewa; Skotheim, Rolf I

    2007-01-01

    The carcinoma in situ (CIS) stage is the common precursor of testicular germ cell tumours (TGCTs) that arise in young adults. Within the past decade genome wide gene expression tools have been developed and have greatly advanced the insight into the biology of TGCTs. Two independent data sets on global gene expression in testicular CIS have been previously published. We have merged the two data sets on CIS samples (n = 6) and identified the shared gene expression signature in relation to express...

  9. Recovery of spermatogenesis after microsurgical subinguinal varicocele repair in azoospermic men based on testicular histology

    Directory of Open Access Journals (Sweden)

    Sandro C. Esteves

    2005-12-01

    Full Text Available OBJECTIVE: Analyze whether testicular histologic patterns from a group of azoospermic men with varicocele is predictive of treatment outcome after subinguinal microsurgical varicocele repair. MATERIALS AND METHODS: Seventeen azoospermic men underwent bilateral open single testis biopsy and microsurgical subinguinal repair of clinical varicoceles. RESULTS: Histopathology of testicular biopsies revealed hypospermatogenesis (HYPO in 6 men, maturation arrest (MA in 5, and Sertoli cell-only (SCO in 6. Overall, presence of spermatozoa in the ejaculates was achieved in 47% (8/17 of men after varicocele repair, but only 35% (6/17 of them had motile sperm in their ejaculates. Only men with testicular histology revealing HYPO (5/6 or maturation arrest (3/5 had improvement after surgery. Median (25% - 75% percentile postoperative motile sperm count for both groups were 0.9 X 106/mL (0.1-1.8 X 106/mL and 0.7 X 106/mL (0.1-1.1, respectively (p = 0.87. The mean time for appearance of spermatozoa in the ejaculates was 5 months (3 to 9 months. One (HYPO of 8 (12.5% men who improved after surgery contributed to an unassisted pregnancy. Postoperative testicular biopsies obtained from patients who had no improvement after surgery revealed that testicular histology diagnosis remained unchanged. Successful testicular sperm retrieval for intracytoplasmic sperm injection (ICSI was achieved in 4 of 9 (44.4% individuals who did not improve after surgery, including 1 man with testicular histology exhibiting SCO. CONCLUSION: Microsurgical varicocele repair in nonobstructive azoospermic men with clinical varicoceles can result in sperm appearance in the ejaculate when hypospermatogenesis or maturation arrest is found on testicular histology diagnosis.

  10. Recovery of spermatogenesis after microsurgical subinguinal varicocele repair in azoospermic men based on testicular histology