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Sample records for quiste epidermoide testicular

  1. Bilateral Testicular Epidermoid Cysts

    Norman Loberant; Shweta Bhatt; Edward Messing; Dogra, Vikram S.

    2011-01-01

    Testicular epidermoid cysts are the most common benign tumors of the testes, but account for only 1-2% of all testicular tumors. In a young man presenting with a testicular mass, a high index of suspicion must be maintained for the malignant testicular germ cell tumor, which is 50-times more common than testicular epidermoid cyst. Bilateral testicular epidermoid cysts are a very rare condition, with only a few reports in the literature. It is extremely important in this condition to make a co...

  2. Concomitant bilateral testicular epidermoid cysts

    Epidermoid cyst of the testis is a rare benign germ tumor, comprising 1-2% of all resected benign testicular masses. Approximately 300 cases have been reported to date. Unilateral involvement has often been reported in the English literature. However, bilateral occurrence is very rare and to the best of our knowledge, there only 3 previous reports of bilateral testicular epidermoid cysts. The fact that they are completely benign makes them amenable to treatment by local excision, thereby saving patient from orchidectomy. Recognition of their characteristic ulatrsonographic features is very important to avoid unnecessary intervention. We present here, a case of bilateral epidermoid cyst in which characteristic ultrasound (US) findings allowed testis-sparing enucleation instead of radical orchiectomy. (author)

  3. Epidermoid Cyst of the Testicle: Unusual Magnetic Resonance Imaging Findings

    Epidermoid cyst of the testis is an uncommon benign tumor that can be treated by organ-preserving surgery when diagnosed preoperatively. Although some sonographic characteristics may be suggestive of epidermoid cysts, sonography is not completely diagnostic. Magnetic resonance imaging (MRI) findings may provide support for the diagnosis of epidermoid cysts. The MRI findings of testicular epidermoid cysts have been reported as either bull's eye or target in appearance, or with signal intensity characteristics more typical of a cystic lesion. In this paper, we present typical sonographic and unusual MRI findings of a testicular epidermoid cyst

  4. Epidermoid cyst of the testis: a case report

    Docal, I.; Crespo, C.; Pardo, A.; Prieto, A.; Alonso, P. [Servicio de Radiologia, Hospital Da Costa, Burela (Lugo) (Spain); Calzada, J. [Servicio de Anatomia Patologica, Hospital Da Costa, Burela (Lugo) (Spain)

    2001-05-01

    Epidermoid cyst of the testis is an uncommon benign tumour, with an overall incidence of 1-2 % of all resected testicular masses. When imaging findings suggest that an intratesticular mass is likely to be an epidermoid cyst, conservative management (enucleation with testicular preservation) can be performed rather than orchidectomy. This case report records an epidermoid cyst in a 12-year-old boy in whom the US findings allowed testis-sparing surgery instead of orchidectomy. (orig.)

  5. Quistes de los maxilares

    Ivan Alberto Manotas Arevalo

    2013-12-01

    Full Text Available Los Grandes Quistes de los Maxilares han estado vinculados siempre a la humanidad, desde tiempos remotos, pues han sido halladas en restos de especimenes fosiles, han llamado la atencion de los clínicos, en torno a su etiologia, en la que se ha introducido la participacion de la genetica, (demostrada en el desarrollo de los queratoquistes maxilares, la fisiopatologia, caracteristicas histologicas (inmunohistoquimica, posibilidades diagnosticas por la imagen, (como la tomografia computarizada y la resonancia nuclear magnetica y otras pruebas. Además llaman la atención al estudio, por sus alternativas de manejo especialmente las formas radicales, y el analisis de asociaciones a otras patolo-gias benignas y malignas, y de la recurrencia muy alto de algunas de estas lesiones. Mucho se ha desarrollado para elucidar su naturaleza real, estadificar adecuadamente la lesion descartando asocia-ciones patologicas sindromicas, indicar un tratamiento apropiado, y realizar seguimientos a largo plazo. Este articulo pretende recaudar una information general que de parametros para abordar el estudio de los quistes maxilares a partir de la presentacion de un caso clinico.

  6. Epidermoid cyst of the testis: An atypical sonographic appearance.

    Chen, Shu-Ting; Chiou, Hong-Jen; Pan, Chin-Chen; Shen, Shu-Huei; Chou, Yi-Hong; Tiu, Chui-Mei; Wang, Hsin-Kai; Lai, Yi-Chen; Lin, Yung-Hui; Wang, Jane; Chang, Cheng-Yen

    2016-09-01

    Epidermoid cysts are rare. They represent the most common benign tumor of the testis. The sonographic appearances of testicular epidermoid cysts usually include avascular, mostly lamellated, heterogeneous internal echotexture, with hypoechoic and hyperechoic concentric rings, accounting for the typical onion-ring appearance. On MRI, epidermoid cysts show a low-signal-intensity center, with internal concentric rings of alternating high- and low-signal intensity on T2-weighted images, which correlates with the onion-ring appearance. We report a patient with testicular epidermoid cyst with atypical ultrasound and MRI appearances that led to the erroneous initial diagnosis of "burned-out" tumor. © 2016 Wiley Periodicals, Inc. J Clin Ultrasound 44:448-451, 2016. PMID:27028726

  7. Epidermoid cyst post dermofasciectomy.

    Henry, Francis P

    2010-01-01

    We report the finding of an unusual presentation of an epidermoid cyst 3 years following dermofasciectomy for Dupuytren\\'s disease. Epidermoid cysts remain a rare entity in the palmoplanter distribution but also a very unusual finding within the confines of a full thickness skin graft.

  8. Quistes no funcionantes de paratiroides

    Pardal Refoyo, José Luis; Ursúa Sarmiento, Inmaculada

    2011-01-01

    [ES] Los quistes de paratiroides son entidades clínicas infrecuentes. Suelen ser asintomáticos y aparecer incidentalmente durante una exploración cervical por imagen o durante una cervicotomía. El diagnóstico definitivo se establece tras la demostración de PTH en el líquido intraquístico o mediante técnicas de inmunohistoquímica. Su origen es epitelial, probablemente de las bolsas faríngeas III y IV. Clásicamente se clasifican en funcionantes (denominados pseudoquistes, asociados a hiperparat...

  9. Differentiated nasosinusal epidermoid carcinoma

    Two case reports of young patients, who were treated in the Otolaryngology Department from 'Dr. Joaquin Castillo Duany' Teaching Clinical Surgical Hospital in Santiago de Cuba are presented. One of the cases presented nasal obstruction, rhinorrhoea and facial pain, for 7 months; the other one presented an increase of volume in the right ocular globe. In both, the results of the biopsy confirmed the diagnosis of differentiated nasosinusal epidermoid carcinoma

  10. Ultrasonographic findings of testicular tumors: Correlation with pathologic findings

    Lee, Yong Joo; Koh, Byung Hee; Oh, Jae Cheon; Kim, Bong Soo; Kim, Yong Soo; Rhim, Hyen Chul; Cho, On Koo; Hahm, Chang Kok; Park, Hae Young; Lee, Jung Dal [Hanyang University College of Medicine, Seoul (Korea, Republic of)

    1999-03-15

    Scrotal sonography is a valuable tool for assessing the testis and surrounding structures, and has become the imaging modality of choice for evaluation of the scrotum. Scrotal sonography is also helpful for differentiating cystic from slid mass and testicular from extratesticular mass, but is sometimes difficult in differentiating malignant tumor from various benign conditions such as epidermoid cyst, focal orchitis, testicular hematoma, and abscess. We demonstrate the sonographic findings of the various testicular mass, and correlation with pathologic findings.

  11. Testicular cancer

    ... health care provider if you have symptoms of testicular cancer. Prevention Performing a testicular self-examination (TSE) each month may help detect testicular cancer at an early stage, before it spreads. Finding ...

  12. Testicular Exams

    ... Can I Help a Friend Who Cuts? Testicular Exams KidsHealth > For Teens > Testicular Exams Print A A ... in the habit of regular testicular exams. The Exam Your doctor should examine your testicles at least ...

  13. [Giant intradiploic infratentorial epidermoid cyst].

    Alberione, F; Caire, F; Fischer-Lokou, D; Gueye, M; Moreau, J J

    2007-10-01

    Epidermoid cysts are benign, uncommon lesions (1% of all intracranial tumors). Their localization is intradiploic in 25% of cases, and exceptionally subtentorial. We report here a rare case of giant intradiploic infratentorial epidermoid cyst. A 74-year old patient presented with recent diplopia and sindrome cerebellar. CT scan and MR imaging revealed a giant osteolytic extradural lesion of the posterior fossa (5.2 cm x 3.8 cm) with a small area of peripheral enhancement after contrast injection. Retrosigmoid suboccipital craniectomy allowed a satisfactory removal of the tumor, followed by an acrylic cranioplasty. The outcome was good. Neuropathological examination confirmed an epidermoid cyst. We review the literature and discuss our case. PMID:18008017

  14. Recurrent intramedullary epidermoid cyst of conus medullaris.

    Fleming, Christina

    2011-01-01

    Spinal intramedullary epidermoid cyst is a rare condition. Recurrent epidermoid cyst in the spine cord is known to occur. The authors describe a case of recurrent conus medullaris epidermoid cyst in a 24-year-old female. She initially presented at 7 years of age with bladder disturbance in the form of diurnal enuresis and recurrent urinary tract infection. MRI lumbar spine revealed a 4 cm conus medullaris epidermoid cyst. Since the initial presentation, the cyst had recurred seven times in the same location and she underwent surgical intervention in the form of exploration and debulking. This benign condition, owing to its anatomical location, has posed a surgical and overall management challenge. This occurrence is better managed in a tertiary-care centre requiring multi-disciplinary treatment approach.

  15. Orbital dermoid and epidermoid cysts: Case study

    Veselinović Dragan; Krasić Dragan; Stefanović Ivan; Veselinović Aleksandar; Radovanović Zoran; Kostić Aleksandar; Cvetanović Marija

    2010-01-01

    Introduction. Dermoid and epidermoid cysts of the orbit belong to choristomas, tumours that originate from the aberrant primordial tissue. Clinically, they manifest as cystic movable formations mostly localized in the upper temporal quadrant of the orbit. They are described as both superficial and deep formations with most frequently slow intermittent growth. Apart from aesthetic effects, during their growth, dermoid and epidermoid cysts can cause disturbances in the eye motility, and i...

  16. Testicular self-exam

    Screening - testicular cancer - self-exam; Testicular cancer - screening - self-exam ... A testicular self-exam is done to check for testicular cancer . Testicles have blood vessels and other structures that can make the exam ...

  17. Testicular Injuries

    ... your testicles might get hit or kicked, like football, hockey, soccer, or karate. An athletic supporter, or ... a Guy. How Can I Talk to My Female Doctor About Certain Things? Testicular Exams How to ...

  18. Quiste coloide del tercer ventrículo

    Juan Dávila Meneses

    2012-09-01

    Full Text Available Los quistes coloides son lesiones intracraneales con una incidencia calculada en tres individuos por millón de personas en un año. Son tumores benignos de la porción anterosuperior del tercer ventrículo. El flujo normal del líquido cefalorraquídeo puede ser interrumpido por un gran quiste que obstruya el foramen de Monro. Los signos y síntomas asociados engloban un espectro amplio de características, desde una cefalea no específica hasta datos de hipertensión intracraneal; algunos quistes coloides se dan en el comienzo agudo de una hidrocefalia y pueden llevar a una muerte súbita. Caso: presentamos el caso de un adolescente masculino de 13 años de edad, de raza negra, quien dos días antes de su fallecimiento había manifestado cefalea. Al examen de autopsia se evidenció un quiste coloide del tercer ventrículo que produjo una hidrocefalia aguda obstructiva, con edema cerebral severo y herniación de amígdalas cerebelosas. En este artículo comentamos las características principales del quiste coloide y realizamos una breve revisión bibliográficaColloid cysts are intracranial lesions with an estimated incidence of three individuals per million people per year. They are benign tumors of the anterior portion of the third ventricle. The normal flow of cerebrospinal fluid may be interrupted by a large cyst obstructing the foramen of Monro. The signs and symptoms associated cover a wide range of features, from a non-specific headaches to intracranial hypertension data, some colloid cysts occur in the acute onset of hydrocephalus and can lead to sudden death. Case: We present the case of an adolescent male 13 years of age, black race, who two days before his death had expressed headache. On examination autopsy showed a third ventricular colloid cyst that caused acute obstructive hydrocephalus with severe cerebral edema and herniation of cerebellar tonsils. In this article we discuss the main features of the colloid cyst and performed

  19. Unusual Cases of Epidermoid cyst: Case Series

    Lalita Yadav

    2013-09-01

    Full Text Available In the oro-facial region cystic lesions of different etiologies are encountered owing to the presence of the teeth in the jaw bones. A bewildering variety of developmental, odontogenic and non-odontogenic cysts are seen. Epidermoid cyst is a rare developmental cyst of the oro-facial region which results from entrapped epidermal elements without adnexal appendages. Dermoid and epidermoid cysts occur in oro-facial region with an incidence of 6.9-7% and represents less than 0.01% of all oral cavity cysts. Here we report two cases of epidermoid cysts occurring at unusual locations involving upper left maxillary region lateral to the nose and pinna of the ear.

  20. Unusual Cases of Epidermoid cyst: Case Series

    Lalita Yadav; Geetpriya Kaur; Naveen Puri; Varun Rastogi; Rachna Sharma

    2013-01-01

    In the oro-facial region cystic lesions of different etiologies are encountered owing to the presence of the teeth in the jaw bones. A bewildering variety of developmental, odontogenic and non-odontogenic cysts are seen. Epidermoid cyst is a rare developmental cyst of the oro-facial region which results from entrapped epidermal elements without adnexal appendages. Dermoid and epidermoid cysts occur in oro-facial region with an incidence of 6.9-7% and represents less than 0.01% of all oral cav...

  1. Extensive Epidermoid Cyst and Breathing Difficulty

    Ciro Dantas Soares

    2015-01-01

    Full Text Available Epidermoid cysts are common cystic lesions in the skin, ovaries, and testicles, but their occurrence in the oral cavity is uncommon. They consist of cysts delimited by a fibrous capsule without cutaneous annexes and are lined by stratified squamous epithelium. The differential diagnosis includes ranula, dermoid cysts, and lingual thyroid. Despite their benign presentation, these cysts can cause functional limitations, requiring special clinical attention for extensive lesions located in regions that preserve vital structures. This paper aims to report a case of epidermoid cyst in patient with swallowing and breathing difficulty, highlighting the clinical and surgical planning.

  2. Testicular Cancer

    ... of skin behind the penis. You can get cancer in one or both testicles. Testicular cancer mainly affects young men between the ages of ... undescended testicle Have a family history of the cancer Symptoms include pain, swelling, or lumps in your ...

  3. Testicular microlithiasis and testicular cancer

    Pedersen, Malene Roland; Rafaelsen, Søren Rafael; Møller, Henrik;

    2016-01-01

    2015. Relevant studies were selected by reading the title and abstract by two of the authors. Studies were included if TML was diagnosed by ultrasonography and a risk condition was reported. Studies were only eligible if the particular risk condition was reported in more than one article. RESULTS: In...... total, 282 abstracts in were identified. Based on title and abstract the eligibility was assessed and 31 studies were included. Five conditions in relation to TML and testicular cancer emerged: Down syndrome, McCune-Albright syndrome, cryptorchidism, infertility and familial disposition of testicular...

  4. Manejo clínico del quiste periapical

    Clara Vergara Hernández

    2013-01-01

    ResumenEl quiste periapical es una lesión inflamatoria de los maxilares formada en el periápice de dientes con pulpa necrótica e infectada siendo una secuela directa de un granuloma apical, están asociados a la raíz dentaria y se encuentran con mayor frecuencia en el maxilar superior. Por lo general no provocan síntomas y su lenta evolución hace que el paciente no se percate del mismo hasta que aparece la asimetría facial. Se presenta un caso correspondiente a un paciente masculino con lesión...

  5. Epidermoid cyst of clitoris mimicking clitoromegaly

    Aggarwal Satish

    2010-01-01

    Full Text Available Clitoromegaly in pediatric and adolescent age group is usually indicative of a disorder of sexual differentiation. We report a girl child presenting with clitoral enlargement due to an epidermoid cyst. The cyst was excised with complete cosmetic recovery.

  6. Intracortical epidermoid cyst of the tibia

    Epidermoid cyst in a long bone is an extremely rare condition. The authors describe such a tumor located in the cortex of the tibia in a 21-year-old woman. She was successfully treated with curettage and autogenous bone grafting. (orig.)

  7. Estudio de la fertilidad y viabilidad de quistes hidatídicos ovinos

    García Llamazares José Luis

    1997-01-01

    Full Text Available FUNDAMENTO: La finalidad de este trabajo es analizar la fertilidad de los quistes hidatídicos de origen ovino, especie de gran interés epidemiológico en la hidatidosis, y la adecuación del gerbillo (Meriones unguiculatus como modelo experimental para el estudio "in vivo" de dicha hidatidosis, fase preliminar de posteriores estudios terapeúticos. MÉTODOS: Se ha realizado un estudio de la fertilidad y viabilidad de quistes hidatídicos procedentes de pulmones e hígados de ganado ovino de Castilla y León a través del examen y evaluación de una serie de parámetros entre los que figura la producción de una hidatidosis secundaria experimental en animales de laboratorio. RESULTADOS: El índice quístico total obtenido fue de 8,57 quistes por ovino infestado (5,97 quistes por pulmón infestado y 5,57 quistes por hígado infestado. El porcentaje de fertilidad obtenido en los quistes hidatídicos de origen ovino que contenían protoescólex viables "in vitro" fue del 43,97% (43,02% en los quistes pulmonares y 46,16% en los quistes hepáticos. La viabilidad "in vivo" de los protoescólex seleccionados se puso de manifiesto al producirse en el 100% de los gerbillos infectados una hidatidosis secundaria experimental. CONCLUSIONES: Se destaca la validez de los criterios utilizados para estudiar la viabilidad "in vitro" de los protoescólex procedentes de quistes hidatídicos de origen ovino. La hidatidosis secundaria producida en gerbillos nos conduce a considerarlos como especie de experimentación adecuada para la investigación "in vivo" de la hidatidosis de origen ovino.

  8. Testicular torsion

    Brasso, K; Andersen, L; Kay, L; Wille-Jørgensen, P; Linnet, L; Egense, J

    1993-01-01

    Thirty-five patients were examined 6-11 years after operation for torsion of the testis. Loss of testicular tissue was significantly associated with long preoperative duration of symptoms and with low postoperative sperm counts. The sex hormones were normal in the majority of patients but there w...... the sperm count and concentration. Measurement of carnitine levels in seminal plasma, as a sign of vas deferens obstruction or dysfunction of epididymis, and of autoantibodies against spermatozoa revealed no significant findings....

  9. Testicular lymphoma

    Møller, Michael Boe; d'Amore, F; Christensen, Bjarne Egelund

    1994-01-01

    In a Danish population-based non-Hodgkin's lymphoma registry, 2687 newly diagnosed patients were registered from 1983 to 1992. 39 had testicular involvement (TL) (incidence 0.26/10(5)/year). Median age was 71 years. 24 cases had localised and 15 had disseminated disease. Histologically, all cases...... score (WHO 3-4). It is suggested that the treatment of stage IE/IIE TL should include early CCT and CNS prophylaxis....

  10. Carcinoma en quiste tirogloso Carcinoma in thyroglosal duct cyst

    M.E. Storani

    2010-09-01

    Full Text Available El carcinoma diferenciado de tiroides en quiste tirogloso (CaQT es una rara entidad. En diferentes series de pacientes operados por quistes tiroglosos su incidencia fue del 0.7 al 1.07%. Luego de la extirpación del quiste por el procedimiento de Sistrunk, no hay consenso sobre la indicación de tiroidectomía total, radioablación y/o terapéutica supresiva con levotiroxina. El objetivo del Departamento de tiroides de SAEM, fue evaluar: formas de presentación, evolución clínica, métodos diagnósticos de utilidad y tratamiento para consensuar futuras conductas. Material y Métodos: Estudio multicéntrico, retrospectivo en 22 pacientes entre 10 a 69 años, 15 mujeres y 7 varones. Resultados: El tamaño de los quistes osciló entre 1 y 8 cm (Mediana= 3.0 cm, Χ ± DS= 3.7 ± 2.2 cm. La mitad de los pacientes presentó crecimiento del quiste en los 6 meses previos a la cirugía. La punción resultó sospechosa en 2/5 quistes y positiva en uno. La ecografía tiroidea evidenció nódulos en 4/13 casos (30%. Se realizó tiroidectomía en 17/22 pacientes (total: 15 y subtotal: 2. La histología del CaQT demostró carcinoma papilar en 21 y carcinoma folicular en uno. Hubo coexistencia de cáncer intratiroideo en el 23.5% de los casos, ninguno multicéntrico. Dos pacientes presentaron metástasis ganglionares y otro tuvo compromiso muscular (ninguno de ellos coexistió con cáncer intratiroideo. Se radioablacionó a 13 pacientes. En 9/11 pacientes la tiroglobulina permaneció indetectable durante el seguimiento (1 a 14 años. Conclusiones: 1 Realizar ecografía de cuello y punción ecoguiada a todo paciente con quiste tirogloso. 2 En caso de CaQT combinar simultáneamente tiroidectomía total y procedimiento de Sistrunk. 3 Evaluar radioablación complementaria y tratamiento supresivo con levotiroxina en cada caso. 4 Efectuar el seguimiento tal como en los carcinomas ortotópicos.Differentiated thyroid carcinoma (DTC in thyroglosal duct cyst (TGDC is

  11. Epidermoid carcinoma of the conjunctiva. Case report

    María Adela LLull Tombo

    2011-12-01

    Full Text Available Se presenta el caso de un paciente de 76 años de edad con un carcinoma epidermoide de conjuntiva.  La manifestación clínica principal fue la molestia, el dolor y el ojo rojo. Al examen físico ocular se encontró lesión blanquecina, con vasos sanguíneos en el ángulo interno, por encima del pterigion en ojo derecho. Se diagnosticó como carcinoma epidermoide de la conjuntiva, el cual evolucionó de forma rápida e invasiva. Se intervino quirúrgicamente en tres ocasiones debido a las recurrencias.

  12. Carcinoma epidermoide del conducto auditivo externo

    Javier Alfonso Rodríguez

    2009-02-01

    Full Text Available Acude a la consulta de Otorrinolaringología un paciente masculino de 43 años de procedencia urbana que comienza con una otorrea de larga evolución (aproximadamente dos años, para la que llevó numerosos tratamientos para la otitis externa que presentaba, con estos antecedentes y lo constatado al examen se decide realizar toma de muestra (biopsia de la zona, diagnosticándose un Carcinoma Epidermoide, del conducto auditivo externo, patología poco frecuente en nuestro medio.A 43 years-old, urban, male patient assists the consultation of Otolaryngology with a long evolving otorrea (around two years, receiving several treatments against the external otitis he suffered. With those antecedents and what we found when examining him, we decided to take a sample (biopsy of the area, diagnosing an epidermoid carcinoma of the left external canal, an infrequent pathology in our settings.

  13. High-density intracranial epidermoid tumors

    An intracranial epidermoid tumor appears as a low-density lesion on CT. This is a report on 3 cases of high-density intracranial epidermoids, which had been regarded as rare. In Case 1, one continuous tumor was noted in the bilateral cerebellopontine regions. A CT scan showed homogeneous high-density zones in the bilateral cerebellopontine-angle regions, with high-density spots indicating calcifications in the prepontine region. In Case 2, the tumor existed around the medulla and in the upper cervical spinal canal; it also seemed embedded in the pons. This tumor appeared on CT as a homogeneous high-density mass. In Case 3, the tumor was thought to have originated from Meckel's cave and to extend mainly into the extradural space in the middle fossa and in the subdural space in the posterior fossa on the right. On CT, this tumor seemed to be a dumbbell-shaped, inhomogeneous high-density mass which contained some low-density areas and peripheral high-density spots indicating calcifications. An obvious contrast enhancement was noted along the margin of the tumor. In each case, dark brown contents, indicating the existence of blood components, were obtained by surgery. These blood components are assumed to be the cause of the high density on CT. Moreover, in Case 3, the microscopic findings of operated-on specimens showed intramural hemorrhage. There were neovascularities in the cyst wall due to the organization of the blood components. It was considered that the blood components in the cystic cavity were the result of a dissection of the intramural hemorrhage. The extravasation of the contrast material from the neovascularities into the extracellular space of the cyst wall was considered to be a main cause of the contrast enhancement in Case 3. Also shown was a characteristic pattern of the extension of epidermoids, a pattern which was revealed by reviewing the reported cases of epidermoids and our own cases. (author)

  14. Epidermoid carcinoma of the external auditory canal

    A 43 years-old, urban, male patient assists the consultation of Otolaryngology with a long evolving otorrhea (around two years), receiving several treatments against the external otitis he suffered. With those antecedents and what we found when examining him, we decided to take a sample (biopsy) of the area, diagnosing an epidermoid carcinoma of the left external canal, an infrequent pathology in our settings

  15. Orbital dermoid and epidermoid cysts: Case study

    Veselinović Dragan

    2010-01-01

    Full Text Available Introduction. Dermoid and epidermoid cysts of the orbit belong to choristomas, tumours that originate from the aberrant primordial tissue. Clinically, they manifest as cystic movable formations mostly localized in the upper temporal quadrant of the orbit. They are described as both superficial and deep formations with most frequently slow intermittent growth. Apart from aesthetic effects, during their growth, dermoid and epidermoid cysts can cause disturbances in the eye motility, and in rare cases, also an optical nerve compression syndrome. Case Outline. In this paper, we described a child with a congenital orbital dermoid cyst localized in the upper-nasal quadrant that was showing signs of a gradual enlargement and progression. The computerized tomography revealed a cyst of 1.5-2.0 cm in size. At the Maxillofacial Surgery Hospital in Niš, the dermoid cyst was extirpated in toto after orbitotomy performed by superciliary approach. Postoperative course was uneventful, without inflammation signs, and after two weeks excellent functional and aesthetic effects were achieved. Conclusion. Before the decision to treat the dermoid and epidermoid cysts operatively, a detailed diagnostic procedure was necessary to be done in order to locate the cyst precisely and determine its size and possible propagation into the surrounding periorbital structures. Apart from cosmetic indications, operative procedures are recommended in the case of cysts with constant progressions, which cause the pressure to the eye lobe, lead to motility disturbances and indirectly compress the optical nerve and branches of the cranial nerves III, IV and VI.

  16. Intraosseous Epidermoid Cyst Associated with Impacted Mandibular Wisdom Teeth: An Uncommon Entity

    Toptas, Orcun; Akkas, Ismail; TEK, Mustafa; Ozan, Fatih; Boran, Cetin

    2014-01-01

    Epidermoid and dermoid cysts of the jaws are seen rarely. The formation theories of the intraosseous epidermoid cyst (IEC) are not clear. The radiographic appearance is similar with unilocular cysts. Surgical enucleation is the suggested treatment method for epidermoid cysts. This case report presents bilateral mandibular intraosseous epidermoid cysts with impacted wisdom teeth which is the first documented case in the literature.

  17. Management of Epidermoid Carcinoma of the anus

    In two unselected, consecutive and population-based patient materials from two regions in Sweden, different treatment modalities in patients with epidermoid carcinoma of the anus have been evaluated. By using a primary radiotherapeutic approach, combined with surgery in patients with large and/or less radiosensitive tumors, considerably more surviving patients can be disease-free in the long term compared with a primarily surgical approach. In addition, several patients will have preserved anal function. Based upon these data together with the experience described in the literature, we conclude that surgery is no longer the primary treatment of choice in patients with anal carcinoma. (authors)

  18. Testicular germinal tumors

    This work is about diagnosis, treatment and monitoring of testicular germinal tumors. The presumed diagnosis is based in the anamnesis, clinical examination, testicular ultrasound and tumor markers. The definitive diagnosis is obtained through the inguinal radical orchidectomy

  19. Chemotherapy for Testicular Cancer

    ... chemotherapy and stem cell transplant for testicular cancer Chemotherapy for testicular cancer Chemotherapy (chemo) is the use ... Symptoms of Cancer Treatments & Side Effects Cancer Facts & Statistics News About Cancer Expert Voices Blog Programs & Services ...

  20. Manejo clínico del quiste periapical

    Clara Vergara Hernández

    2013-10-01

    Full Text Available ResumenEl quiste periapical es una lesión inflamatoria de los maxilares formada en el periápice de dientes con pulpa necrótica e infectada siendo una secuela directa de un granuloma apical, están asociados a la raíz dentaria y se encuentran con mayor frecuencia en el maxilar superior. Por lo general no provocan síntomas y su lenta evolución hace que el paciente no se percate del mismo hasta que aparece la asimetría facial. Se presenta un caso correspondiente a un paciente masculino con lesión de aspecto clínico tumoral en hemicara izquierda. Al examen radiográfico se observa imagen radiolúcida a nivel de incisivo central superior que continua con el ligamento periodontal. Se realiza biopsia por aspiración y basado en el estudio histopatológico, se diagnostica como quiste periapical. La conducta que se siguió con respecto al tratamiento fue quirúrgica. (DUAZARY 2010, 219 - 222AbstractThe periapical cyst it is an inflammatory injury of maxillaries formed in periápice of teeth with necrotic and infected pulp being a direct sequel of granuloma apical, is associate to the dental root and they are most frequently in superior maxilary. By the general they do not cause symptoms and its slow evolution causes that the patient does not notice of he himself until appears the face asymmetry. A case is exposed corresponding to a masculine patient with left injury of tumor like clinical aspect in hemicara. The radiographic examination radiolúcida image at level of superior central incisor is observed that continuous with the periodontal ligament. It makes biopsy by aspiration and based on the histopatológico study, it is diagnosed like periapical cyst. The conduct that was followed with respect to the treatment was surgical.Keywords: Periapical cyst; periapical disease; apical granuloma; periodontal ligament.

  1. Clinical Characteristics of Epidermoid Cysts of the External Auditory Canal

    Kim, Go-Woon; Park, Jang-Hee; Kwon, Oh-Joon; Kim, Dong Hyun

    2016-01-01

    Background and Objectives The epidermoid cyst is a common benign disease of the skin caused by inflammation of hair cortex follicles and proliferation of epidermal cells within the dermis or superficial subcutaneous tissue. The purpose of this study was to investigate the characteristics of epidermoid cysts of the external auditory canal (EAC) by analyzing the clinical and radiologic features. Subjects and Methods The clinical records were retrospectively reviewed for patients diagnosed with epidermoid cyst of the EAC from March 2004 to December 2013. The epidermoid cysts were diagnosed clinically by endoscopy and microscopy examinations and by temporal bone CT images, and were confirmed by histopathologic examination. Characteristics of epidermoid cysts in bony EAC and cartilaginous EAC were compared. Results Eight patients had an epidermoid cyst in the bony EAC and nine patients had one in the cartilaginous EAC. Swelling and otalgia were common symptoms, but 47% of cysts were found incidentally. The mean age of patients was 49.6 years (age range, 26-67 years) in the bony EAC cases and 26.1 years (age range, 6-57 years) in the cartilaginous EAC cases. The mean size of the epidermoid cyst was 3.50 mm (size range, 2-7 mm) in the bony EAC cases and 9.55 mm (size range, 2-20 mm) in the cartilaginous EAC cases. Conclusions Comparison of epidermoid cysts of the bony EAC and the cartilaginous EAC revealed that epidermoid cysts of the bony EAC is usually found incidentally, arose in older patients and had smaller size. PMID:27144232

  2. Giant Pelvic Retroperitoneal Epidermoid Cyst: A Rare Case Report

    F. Z. Fdili Alaoui

    2012-01-01

    Full Text Available Epidermoid cyst is a frequent benign cutaneous tumor. The pelvic localization does not occur very often. The literature that taps into such cases is very limited in scope. Here is a report of a 27-year-old woman with a giant pelvic retroperitoneal epidermoid cyst. The use of ultrasound exploration and computed tomography has indicated ovarian origins. The surgery also revealed a retroperitoneal epidermoid cyst, uterus and ovaries were all intact. The evacuation of a cyst was found to contain lamellas of keratin. Histology permitted us to confirm the diagnosis. The patient was faring well after two years of followup.

  3. Giant pelvic retroperitoneal epidermoid cyst: a rare case report.

    Fdili Alaoui, F Z; Oussaden, A; Bouguern, H; El Fatemi, H; Melhouf, M A; Amarti, A; Ait Taleb, K

    2012-01-01

    Epidermoid cyst is a frequent benign cutaneous tumor. The pelvic localization does not occur very often. The literature that taps into such cases is very limited in scope. Here is a report of a 27-year-old woman with a giant pelvic retroperitoneal epidermoid cyst. The use of ultrasound exploration and computed tomography has indicated ovarian origins. The surgery also revealed a retroperitoneal epidermoid cyst, uterus and ovaries were all intact. The evacuation of a cyst was found to contain lamellas of keratin. Histology permitted us to confirm the diagnosis. The patient was faring well after two years of followup. PMID:23150734

  4. Epidermoid cyst causing hemifacial spasm epidermoid cyst in cerebellopontine angle presenting with hemifacial spasm

    Murat Alemdar

    2012-01-01

    Full Text Available Hemifacial Spasm (HS occurs idiopathically or secondary to the lesions compressing the root exit zone of the facial nerve symptomatically. Symptomatic HS is generally due to vascular compression. We report on a 23-year-old male with right sided HS for a month. Magnetic resonance imaging (MRI of the brain revealed a well-demarcated epidermoid cyst in the right cerebellopontine cistern. It was hypointense on T1-weighted imaging, hyperintense on T2-weighted imaging without contrast enhancement, hyperintense on DWI, and slightly hypointense on ADC relative to the brain. Although it caused shifting of the pons and medulla to the left side and compression of the right cerebellar peduncles and fourth ventricle, the sole symptom of the patient was HS. Clinicians are advised to request MRI/scan for brainstem lesions from the patients with HS. Epidermoid cysts in cerebellopontine cistern may present with HS as the sole symptom.

  5. Quiste subaracnoideo y displasia del ala mayor del esfenoides en neurofibromatosis

    J. Cortés-Arreguín; D. Palafox; Molina, F

    2015-01-01

    Los quistes subaracnoideos representan menos del 1% de los tumores de ocupación intracraneal. Hay pocas publicaciones acerca de quistes subaracnoideos del lóbulo temporal con remodelación de la cavidad orbitaria, pero no existen en relación al tratamiento reconstructivo de la cavidad orbitaria en esta patología. Presentamos el caso clínico de un varón de 44 años de edad con diagnóstico de neurofibromatosis tipo 1, aumento progresivo de volumen del ojo y párpado izquierdos de 40 años de evoluc...

  6. Quistes del rafe medio del pene. Presentación de dos casos

    Niurka García Sosa; Francisco J Fong Aldama

    2014-01-01

    Los quistes del rafe medio del pene son lesiones benignas, infrecuentes en urología pediátrica, y usualmente asintomáticos. Se localizan en la región parameatal y borde inferior del prepucio. Se presentaron dos casos que acudieron a consulta de Urología, por el hallazgo del quiste por parte de los padres de los pacientes. Ambos quisten tenían de 1 a 2 cm de diámetro. Ninguno de los casos reportados se les había realizado la circuncisión previamente. A los dos casos se les hizo la marsupializa...

  7. Estudio de la fertilidad y viabilidad de quistes hidatídicos ovinos

    García Llamazares José Luis; Álvarez de Felipe Ana Isabel; Redondo Cardeña Pedro Angel; Prieto Fernández Julio Gabriel

    1997-01-01

    FUNDAMENTO: La finalidad de este trabajo es analizar la fertilidad de los quistes hidatídicos de origen ovino, especie de gran interés epidemiológico en la hidatidosis, y la adecuación del gerbillo (Meriones unguiculatus) como modelo experimental para el estudio "in vivo" de dicha hidatidosis, fase preliminar de posteriores estudios terapeúticos. MÉTODOS: Se ha realizado un estudio de la fertilidad y viabilidad de quistes hidatídicos procedentes de pulmones e hígados de ganado ovino de Castil...

  8. Comportamiento del quiste branquial en pacientes del Hospital General Docente "Ciro Redondo García", Artemisa, 1993-2009

    Juan Carlos Quintana Díaz; Josefa Dolores Miranda Tarragó; Mayrim Quintana Giralt

    2012-01-01

    El quiste branquial de origen congénito que aparece en la región lateral del cuello es, con frecuencia, motivo de consulta. Se tuvo como objetivo determinar el comportamiento de los quistes branquiales en el Hospital "Ciro Redondo García", de Artemisa en el periodo de 1993 al 2009. Se realizó un estudio descriptivo transversal de los quistes branquiales diagnosticados en pacientes intervenidos quirúrgicamente en el Servicio de Cirugía Maxilofacial. Se estudiaron la edad, el sexo, el color de ...

  9. Do We Know What Causes Testicular Cancer?

    ... Do we know what causes testicular cancer? Can testicular cancer be prevented? Previous Topic What are the risk factors for testicular cancer? Next Topic Can testicular cancer be prevented? Do we know what causes testicular cancer? The ...

  10. Epidermoid cyst of the posterior fossa: a case report Cisto epidermoide da fossa posterior: relato de caso

    Eduardo Cambruzzi

    2011-02-01

    Full Text Available Epidermoid cysts of the central nervous system are uncommon conditions, which are frequently located in the cerebellopontine angle and around the pons. They are covered with keratinized squamous epithelium and keratin lamella, which give its contents a soft, white-pearly appearance. Epidermoid cysts are mostly originated from malformations, presumably associated with surface elements of the nervous system ectoderm during the closure of the neural groove or formation of secondary cerebral vesicles. The authors describe a case of epidermoid cyst in the posterior fossa causing hydrocephalus and review morphologic and diagnostic criteria of this lesion.Os cistos epidermoides do sistema nervoso central (SNC são condições incomuns, estando localizados mais frequentemente no ângulo pontocerebelar e ao redor da ponte. Eles são revestidos por epitélio escamoso queratinizado e lamelas de queratina, tornando seu conteúdo branco-perolado e pastoso. Os cistos epidermoides são, na maioria das vezes, originados de malformações, possivelmente associados ao entremeio de elementos superficiais do ectoderma do SNC durante o fechamento da placa neural, ou formação das vesículas cerebrais secundárias. Os autores descrevem um caso de cisto epidermoide da fossa posterior determinando hidrocefalia e revisam critérios morfológicos e diagnósticos dessa lesão.

  11. Recurrent Perianal Sinus in Young Girl Due To Pre-sacral Epidermoid Cyst

    Jain, V.; Misra, S; Tiwari, S; Rahul, K; Jain, H.

    2013-01-01

    Pre-sacral epidermoid cysts are rare development cysts resulting from dysembryogenesis mostly diagnosed in middle aged women. We report a case of pre-sacral epidermoid cyst presenting with recurrent perianal sinus in young girl. Generally pre-sacral epidermoid cysts are seen in adult age group but it is rare presentation in young age group. We report a rare case of presacral epidermoid cyst occurring in a young female.

  12. Epidermoid cyst of the ovay in young woman: A case report

    In general, ovarian epidermoid cysts coexist with surface epithelial ovarian tumors. Pure epidermoid cysts are extremely rare diseases, comprising less than 1% of surface ovarian tumors. We present here a pathologically proven epidermoid cyst of the ovary in a young woman with ultrasonographic and magnetic resonance findings

  13. Epidermoid cyst of the ovay in young woman: A case report

    Hong, Jung Hee; Kim, See Hyung; Kang, Yu Na; Kim, Mi Jeong [Keimyung University School of Medicine, Dongsan Medical Center, Daegu (Korea, Republic of)

    2015-06-15

    In general, ovarian epidermoid cysts coexist with surface epithelial ovarian tumors. Pure epidermoid cysts are extremely rare diseases, comprising less than 1% of surface ovarian tumors. We present here a pathologically proven epidermoid cyst of the ovary in a young woman with ultrasonographic and magnetic resonance findings.

  14. En las enfermedades intersticiales difusas,¿todos los quistes son realmente quistes? Diffuse interstitial diseases: are all cysts real cysts?

    Juan Carlos Spina

    2010-04-01

    Full Text Available Propósito: Demostrar que los cortes axiales de tomografía computada de alta resolución (TCAR son insuficientes para una correcta evaluación de las enfermedades pulmonares intersticiales difusas y que adicionar Proyección de Mínima Intensidad (MinIP aumenta la especificidad del diagnóstico. Material y Métodos: Estudios previos donde se observaban quistes pequeños subpleurales se seleccionaron 39 TCAR de 33 pacientes con colagenopatías confirmadas y 6 con enfermedad intersticial idiopática y se los reexaminó entre octubre de 2008 y junio de 2009. El equipo utilizado fue un tomógrafo computado multislice Philips Brillance de 16 canales. Los cortes fueron de 1 mm de espesor, de ápices a bases. La evaluación se realizó con la técnica habitual, adicionando la MinIP en cortes axiales, sagitales y coronales, con rotación del parénquima y especial atención en las áreas que presentaban quistes. Se efectuaron además cortes en espiración. Resultados: De 20 TCAR que mostraban quistes subpleurales con la técnica habitual, 14 (70% correspondieron a bronquioloectasias. En 12 casos, todas las imágenes eran bronquioloectasias; en 2 casos, ellas predominaban, observándose también quistes aislados. Se pudo definir la existencia de quistes verdaderos en 6 casos (30%, todos con Neumonitis Intersticial Usual (NIU. Valor predictivo positivo (VPP de la TCAR para detección de quistes: 30% (IC95% 0.13-0.54. Conclusiones: Los trabajos publicados sobre enfermedades intersticiales se basan en la evaluación con cortes axiales de TCAR y la demostración de quistes es de suma importancia para diferenciar NIU de la Neumonía Intersticial No Específica (NINE. En este estudio, se evidencia que la utilización de MinIP con rotación del parénquima redefine 70% de los quistes como bronquioloectasias. Dado el rol cardinal de la TCAR en la evaluación de las intersticiopatías, es importante un estudio prospectivo de seguimiento con mayor número de

  15. Diffusion-weighted MR imaging (DWI) in two intradural spinal epidermoid cysts

    Thurnher, Majda M. [Medical University of Vienna, Vienna (Austria)

    2012-11-15

    Epidermoid cysts are rare, benign, congenital, slow-growing inclusion cysts. On T1 and T2 weighted NMR images epidermoid cysts show heterogeneity and lack of contrast enhancement. Based on signal intensities on conventional sequences, epidermoid cysts cannot be distinguished from other neoplastic lesions. When located in the spinal cord, differential diagnosis includes ependymoma, astrocytoma, cavernoma and metastasis. Diffusion-weighted imaging (DWI) has been shown to accurately distinguish intracranial epidermoid tumors from arachnoid cysts. DWI findings in two patients with surgically proven epidermoid cysts in the spinal canal are reported.

  16. Testicular self-examination

    ... exam URL of this page: //medlineplus.gov/ency/article/003909.htm Testicular self-exam ... testicles (also called the testes) are the male reproductive organs that produce sperm and the hormone testosterone. They are located in ...

  17. Large and small cells non-keratinizing epidermoid vaginal carcinoma

    Five case reports of patients who were assisted at the cervix Pathology Department from 'Mariana Grajales Coello' Provincial Gynecological Obstetrical Hospital in Santiago de Cuba due to vaginal bleeding, low abdominal pain, leukorrhea and vaginal injuries are presented. The pathological study confirmed the diagnosis of squamous or epidermoid cells carcinoma

  18. Epidermoid carcinomas of the conjunctive with intraorbital and intraocular invasion

    The epidermoid carcinomas of the conjunctive are tumors in general of low incidence with a range between 0.13 and 1.9 cases for 100,000 inhabitants; this incidence is superior however in tropical countries. The incidences reported for intra orbital and intraocular invasive forms have a range between 2 and 12% which demonstrates the aggressive character of this tumor. The handling of epidermoid carcinoma of the conjunctive in initial stages is very conservative, but in their natural history this tumor can invade the ocular globe, orbit, neighboring regions and distant organs, thereby of importance an early diagnosis and an appropriate treatment. Our objective was to know the incidence of epidermoid carcinoma of the conjunctiva with intraocular and intra orbital invasion in the Havana National Oncology Institute. We carry out a retrospective and descriptive study of 18 patients with clinical diagnoses and histology of epidermoid carcinoma of the conjunctiva with orbit infiltration assisted from January of 1995 until December 2003 classified as T4 NO MO. The evaluated parameters were: age, sex, initial treatment and evolution. Middle aged of our serie it was 58.7 years, excisional surgery and deep radiotherapy was the initial treatment applied in 83.33% of the cases. In its evolution eight cases (44.44%) of the patients had unfavorable result and radical surgery was carried out in 50% of the patients. (The author)

  19. Paraurethral cyst. A case report Quiste parauretral. Presentación de un caso

    Emilio Vega Azcúe

    2011-03-01

    Full Text Available The paraurethral or Skene’s duct cyst, is a rare diagnostic entity in a newborn. It represents less than 0,5 % of congenital malformations of the urinary tract. All over the world it is reported an incidence of 1:2000 to 1:7000 in female births. In the newborn, the paraurethral cyst is caused by retention of secretions in the Skene's gland due to the obstruction of its ducts. Most of these cysts decrease in size during the first four to eight weeks, but they may cause symptoms of infection or urinary obstruction. They can also get formed from persistent embryonic remains of the mesonephric ducts (Wolffian duct, known as Gartner cysts and from the occlusion of unfused paramesonephric ducts (Müllerian. The case of a 25-day-old female, diagnosed with paraurethral cyst that underwent surgery and evolved successfully is presented.El quiste parauretral o de Skene, es una entidad de diagnóstico muy raro en el recién nacido, representa menos del 0,5 % de las malformaciones congénitas de las vías urinarias. Se reporta mundialmente una incidencia de 1:2000 a 1:7000 en los nacimientos femeninos. En la recién nacida, el quiste parauretral se origina por la retención de secreciones en la glándula de Skene, debido a la obstrucción de sus conductos. La mayoría de estos quistes disminuyen de tamaño durante las primeras cuatro a ocho semanas, pero pueden presentar síntomas de infección u obstrucción urinaria. También se pueden formar a partir de restos embrionarios persistentes de los conductos mesonéfricos (conductos de Wolf, llamados quistes de Gartner y de la oclusión de los conductos paramesonéfricos no fusionados (Müllerianos. Se presenta el caso de una paciente de 25 días de nacida, de sexo femenino, que se le diagnosticó un quiste parauretral y se le realizó tratamiento quirúrgico, del cual evolucionó de manera satisfactoria.

  20. Inguinal metastases from testicular cancer

    Daugaard, Gedske; Karas, Vladimir; Sommer, Peter

    2006-01-01

    To evaluate the incidence of inguinal metastases in patients with testicular cancer and relapse after initial stage I disease.......To evaluate the incidence of inguinal metastases in patients with testicular cancer and relapse after initial stage I disease....

  1. Testicular calculus: A rare case

    Volkan Sen

    2015-06-01

    Full Text Available ABSTRACTBackground:Testicular calculus is an extremely rare case with unknown etiology and pathogenesis. To our knowledge, here we report the third case of testicular calculus. A 31-year-old man was admitted to our clinic with painful solid mass in left testis. After diagnostic work-up for a possible testicular tumour, he underwent inguinal orchiectomy and histopathologic examination showed a testicular calculus.Case hypothesis:Solid testicular lesions in young adults generally correspond to testicular cancer. Differential diagnosis should be done carefully.Future implications:In young adults with painful and solid testicular mass with hyperechogenic appearance on scrotal ultrasonography, testicular calculus must be kept in mind in differential diagnosis. Further reports on this topic may let us do more clear recommendations about the etiology and treatment of this rare disease.

  2. Comportamiento del quiste branquial en pacientes del Hospital General Docente "Ciro Redondo García", Artemisa, 1993-2009

    Juan Carlos Quintana Díaz

    2012-03-01

    Full Text Available El quiste branquial de origen congénito que aparece en la región lateral del cuello es, con frecuencia, motivo de consulta. Se tuvo como objetivo determinar el comportamiento de los quistes branquiales en el Hospital "Ciro Redondo García", de Artemisa en el periodo de 1993 al 2009. Se realizó un estudio descriptivo transversal de los quistes branquiales diagnosticados en pacientes intervenidos quirúrgicamente en el Servicio de Cirugía Maxilofacial. Se estudiaron la edad, el sexo, el color de la piel, el lado del cuello afectado, el resultado histopatológico y los medios auxiliares empleados. Se encontraron 12 quistes branquiales que afectaron el 50 % de ambos sexos, un 75 % a pacientes entre 15 y 30 años y un 75 % de la piel blanca, un 66,7 % afectó el lado derecho del cuello y en un 100 % de los casos se utilizó la biopsia y el ultrasonido como medios auxiliares para su diagnóstico. Se encontró epitelio escamoso estratificado en un 100 % de los quistes y en un 91,6 % el tejido linfoide. No se encontró predilección por el sexo, la mayoría de los pacientes eran menores de 30 años, de piel blanca y presentaban los quistes en el lado derecho del cuello. En todos los pacientes se empleó la biopsia y el ultrasonido como medios auxiliares de diagnóstico. El epitelio escamoso estratificado y el tejido linfoide fueron los hallazgos histopatológicos más relevantes.

  3. Clinical presentation of intracranial epidermoids: a surgical series of 20 initial and four recurred cases

    Kato, Koichi; Ujiie, Hiroshi; Higa, Takashi; Hayashi, Masataka; Kubo, Osami; Okada, Yoshikazu; HORI, TOMOKATSU

    2010-01-01

    Epidermoids are generally recognized as benign tumors; however, total resection is often difficult. The recurrence from the residual capsule, dissemination of the tumor, and aseptic meningitis are common problems. The aim of the present study was to analyze and report on the clinical characteristics of intracranial epidermoids, particularly complications and cases with a poor clinical outcome. 24 patients with intracranial epidermoids who were treated surgically at Tokyo Women's Medical Unive...

  4. Cytodiagnosis of epidermoid cyst of the upper lip: A common lesion in an uncommon site

    Jyoti Prakash Phukan; Anuradha Sinha; Subrata Pal; Shilpa Jalan

    2014-01-01

    Epidermoid cyst and dermoid cysts are developmental pathologies thought to derive from aberrant ectodermal tissue. They are uncommon in the head and neck region. Rarely, they can be found in the oral cavity and buccal mucosa. However, epidermoid cyst is extremely uncommon in the upper lip and is rarely reported. In this study, we report an uncommon case of epidermoid cyst occurring in the upper lip diagnosed by fine-needle aspiration cytology (FNAC). We present this case because of its extrem...

  5. Intraosseous epidermoid cysts in the distal phalanx of two dogs

    Two dogs were presented with a history of lameness associated with swelling of one of the digits. Radiographs of the affected digits revealed an irregularly mineralized, smoothly marginated proliferative bone lesion in the distal phalanx of one dog and a destructive bony lesion in the distal phalanx of the second dog. The differential diagnosis included nail bed carcinoma, malignant melanoma, osteomyelitis, and subungual keratoacanthoma. Radiographic findings and no response to medical treatment resulted in amputation and submission of the digits for a histopathologic diagnosis. Histologic examination of the distal phalanx of the digits revealed benign epidermoid cysts associated with either bony proliferation or osteolysis. Excision of the lesions was curative. This report presents the clinical, radiographic, and histopathologic findings associated with intraosseous epidermoid cysts in the distal phalanx of two dogs

  6. Identificación de células proliferativas en quistes de Taenia solium

    Miguel Ángel Orrego-Solano; Carla Cangalaya; Nash, Theodore E.; Cristina Guerra-Giraldez

    2014-01-01

    Los neoblastos son células totipotentes, únicas responsables de la proliferación y maduración de tejidos en platelmintos de vida libre. Células similares se han aislado en platelmintos parásitos como Echinococcus. Taenia solium causa la teniasis humana (intestinal) y la cisticercosis en humanos y cerdos. La infección del cerebro con larvas (quistes) de T. solium resulta en neurocisticercosis, hiperendémica en el Perú; su tratamiento se asocia a síntomas neurológicos graves. La capacidad proli...

  7. El quiste óseo aneurismático en niños y adolescentes

    Martínez Jiménez, José Enrique; Pagán Conesa, J. A.; Salinas Gilabert, José E.; Alonso Díaz-Marta, M.

    1999-01-01

    Desde el año 1981 hasta el año 1996 hemos tratado en nuestro servicio un total de 12 pacientes con diagnóstico de Quiste Óseo Aneurismático (QOA). Esta entidad clínico-patológica continúa hoy teniendo un origen incierto que en la mayoría de las ocasiones no puede reconocerse. Los tratamientos empleados fueron: legrado e injerto óseo en siete casos, resección en bloque en tres casos, y en 2 casos tratamiento expectante. Los resultados del tratamiento quirúrgico fueron satisfactorios en el 7...

  8. Quiste del mesenterio intestinal en la edad pediátrica

    Ada Arleny Pérez Mayo; Yordania Velázquez Avila

    2014-01-01

    Se presenta el caso de una paciente de 9 años de edad, ingresada por molestia abdominal en el Hospital Nacional de San Pedro Necta del Departamento de Huehuetenango, en Guatemala. Constituyó una rara lesión intra-abdominal, que pudo provocar abdomen agudo. Fue interpretado inicialmente como quiste de ovario gigante. La ausencia de ecografía abdominal y la presencia de distensión y masa palpable asintomática decidieron la intervención quirúrgica. Se realizó una cuidadosa preparación preoperato...

  9. Lymphoepithelial cyst in the palatoglossus arch Quiste linfoepitelial en el arco palatogloso

    Evanice Maria Marçal Vieira

    2012-12-01

    Full Text Available The objective of this study was to describe a case of a lymphoepithelial cyst in the palatoglossus arch. A 16-years-old black man said that he was observed a lesion in his mouth. On the physical exam, a pedicled, consistent, smooth surface 1.5 x 1 cm lesion, similar in color to the adjacent mucosa, was found. The lesion was surgically removed and the microscopic exam showed mucosal fragments with pedicled lesion; the cystic cavity sometimes lined with pseudostratified cylindrical epithelium and others with stratified squamous flat interface of the epithelium. Around the cyst, a well-delimited mass of lymphoid tissue, presenting lymphoid follicles, was also seen. Lymphoepithelial cyst has clinical characteristics similar to those of others lesions that occur in the oral cavity. The diagnosis should be based on conservative biopsy, with total removal of lesion.El objetivo de este estudio fue describir un caso clínico de quiste linfoepitelial en el arco palatoglosso. Paciente de 16 años de edad, sexo masculino, raza negra, que durante la anamnesis relató que observó una lesión en la boca. Al examen físico se observó una lesión pediculada, de consistencia firme, superficie lisa, de 1,5 x 1,0 cm de tamaño, con color similar al de la mucosa adyacente. La lesión fue removida quirúrgicamente y el examen microscópico mostró fragmentos de mucosa con lesión pediculada, la cavidad del quiste a veces revestida por epitelio cilíndrico pseudoestratificado y otras veces por la interfase plana del epitelio escamosa estratificado. Alrededor del quiste, una masa bien delimitada de tejido linfoide con presencia de folículos linfoides. El quiste linfoepitelial tiene las mismas características clínicas de otras lesiones que ocurren en la cavidad oral, el diagnóstico debe ser realizado por biopsia, de manera conservadora, con eliminación total de la lesión.

  10. Quiste pilonidal gigante en un anciano Giant pilonidal cyst in an elderly man

    Héctor Bell Santos; Marcos Antonio Santos Danger

    2011-01-01

    Se describe el caso clínico de un anciano con quiste pilonidal gigante, cuya información primaria al respecto se obtuvo de la labor de terreno realizada por su médico de familia y anotada en la historia clínica individual del paciente, el cual fue intervenido quirúrgicamente y con éxito en el Servicio de Coloproctología del Hospital General Docente "Dr. Juan Bruno Zayas Alfonso" de Santiago de Cuba en enero de 2010, cuando se efectuó la exéresis total del tumor sin lesionar el recto.A case re...

  11. Treatment of epidermoid tumors with gamma knife radiosurgery: Case series

    Javier A Jacobo Vasquez; Julio R Fonnegra; Juan C Diez; Andres Fonnegra

    2016-01-01

    Background: Epidermoid tumors (ETs) are benign lesions that are treated mainly by means of surgical resection, with overall good results. External beam radiotherapy is an alternative treatment for those recurrent tumors, in which a second surgery might not be the best choice for the patient. A little information exists about the effectiveness of gamma knife radiosurgery for the treatment of newly diagnosed and recurrent ETs. We present three cases of ETs treated with gamma knife radiosurgery....

  12. Intratesticular and intraovarian epidermoid inclusion cysts: report of two cases

    Guilherme José Morgan

    2013-04-01

    Full Text Available Two rare cases of intragonadal epidermoid inclusion cysts are described. Their etiology remains controversial and a possible hypothesis is monodermal abortive teratomas, with no mesodermal and endodermal components. As the ultrasound test results were inconclusive, it became difficult to rule out the possibility of neoplasm. Therefore, patients were submitted to radical therapy. The definitive diagnosis for both cases was provided by the anatomopathological examination.

  13. Testicular schistosomiasis mimicking tumour

    Nicola Mortati Neto

    2004-12-01

    Full Text Available Schistosomiasis or bilharziasis is a disease caused by Schistosoma. When infecting men the most common parasites are Schistosoma mansoni, Schistosoma japonicum and Schistosoma haematobium. The Schistosoma mansoni is the only endemic parasite in Brazil. We present a case of testicular schistosomiasis simulating malignancy. The case was treated successfully by excisional biopsy and praziquantel therapy. A review of the literature is discussed.

  14. Can Testicular Cancer Be Found Early?

    ... staged? Testicular cancer survival rates Previous Topic Can testicular cancer be prevented? Next Topic Signs and symptoms of testicular cancer ... 2016 Back to top » Guide Topics What Is Testicular ... Risk Factors, and Prevention Early Detection, Diagnosis, and Staging Treating Testicular Cancer ...

  15. Quiste gigante de ovario: presentación de un caso

    Mario Joel Arroyo Díaz

    2011-11-01

    Full Text Available Los quistes gigantes de ovario son tumoraciones poco frecuentes en las afecciones ginecológicas. Se presenta el caso de una paciente de 62 años de edad, de color de piel blanca, peso 73 kg. que acudió al Hospital General Docente “Enrique Cabrera” refiriendo aumento progresivo de volumen del abdomen, de un año y medio de evolución sin otro síntoma acompañante en su comienzo, pero en los últimos meses le provocaba falta de aire ante los esfuerzos, orinaba con más frecuencia de lo acostumbrado y con falta de apetito. Se le diagnosticó una masa quística dependiente de ovario, por ultrasonografía y Tomografía Axial Computarizada. Se practicó laparotomía y se resecó quiste de ovario izquierdo de 21 kg. de peso. El estudio anatomopatológico ulterior reportó un cistoadenoma mucinoso de ovario con tumor de Brenner asociado.

  16. Identificación de células proliferativas en quistes de Taenia solium

    Miguel Ángel Orrego-Solano

    2014-12-01

    Full Text Available Los neoblastos son células totipotentes, únicas responsables de la proliferación y maduración de tejidos en platelmintos de vida libre. Células similares se han aislado en platelmintos parásitos como Echinococcus. Taenia solium causa la teniasis humana (intestinal y la cisticercosis en humanos y cerdos. La infección del cerebro con larvas (quistes de T. solium resulta en neurocisticercosis, hiperendémica en el Perú; su tratamiento se asocia a síntomas neurológicos graves. La capacidad proliferativa y el desarrollo de los estadios de T. solium aún no se describen, y no se ha caracterizado los neoblastos de este parásito. Se buscó células proliferativas en quistes de T. solium colectados de un cerdo infectado, que fueron identificadas al replicarse e incorporar el nucleótido bromodesoxiuridina, detectado con un anticuerpo monoclonal. Una línea celular estable de neoblastos sería útil para estudios sistemáticos in vitro sobre eficacia de drogas y sobre la biología de T. solium.

  17. Identificación de células proliferativas en quistes de Taenia solium

    Miguel Ángel Orrego-Solano

    2014-10-01

    Full Text Available Los neoblastos son células totipotentes, únicas responsables de la proliferación y maduración de tejidos en platelmintos de vida libre. Células similares se han aislado en platelmintos parásitos como Echinococcus. Taenia solium causa la teniasis humana (intestinal y la cisticercosis en humanos y cerdos. La infección del cerebro con larvas (quistes de T. solium resulta en neurocisticercosis, hiperendémica en el Perú; su tratamiento se asocia a síntomas neurológicos graves. La capacidad proliferativa y el desarrollo de los estadios de T. solium aún no se describen, y no se ha caracterizado los neoblastos de este parásito. Se buscó células proliferativas en quistes de T. solium colectados de un cerdo infectado, que fueron identificadas al replicarse e incorporar el nucleótido bromodesoxiuridina, detectado con un anticuerpo monoclonal. Una línea celular estable de neoblastos sería útil para estudios sistemáticos in vitro sobre eficacia de drogas y sobre la biología de T. solium.

  18. Quiste del mesenterio intestinal en la edad pediátrica

    Ada Arleny Pérez Mayo

    2014-08-01

    Full Text Available Se presenta el caso de una paciente de 9 años de edad, ingresada por molestia abdominal en el Hospital Nacional de San Pedro Necta del Departamento de Huehuetenango, en Guatemala. Constituyó una rara lesión intra-abdominal, que pudo provocar abdomen agudo. Fue interpretado inicialmente como quiste de ovario gigante. La ausencia de ecografía abdominal y la presencia de distensión y masa palpable asintomática decidieron la intervención quirúrgica. Se realizó una cuidadosa preparación preoperatoria, que incluyó la antisepsia local de la piel y la administración de ceftriaxona, como antibiótico profiláctico. Durante la laparotomía exploradora se constató un quiste gigante del mesenterio del intestino delgado, de 17 cm de longitud, localizado a nivel del íleon terminal y sujeto por un pedículo ampliamente vascularizado. La técnica quirúrgica consistió en la exéresis total de la lesión y no se requirió de resección intestinal ante la ausencia de oclusión intestinal. Los hallazgos anatomo-patológicos informaron proceso benigno. No se reportaron complicaciones y la paciente evolucionó satisfactoriamente, reportándose una estadía hospitalaria de cinco días

  19. Malignant Transformation Six Months after Removal of Intracranial Epidermoid Cyst: A Case Report

    Fayçal Lakhdar

    2011-01-01

    Full Text Available Intracranial epidermoid cysts are uncommon benign tumors of developmental origin; malignant transformation of benign epidermoid cysts is rare, and their prognosis remains poor. We report a case of squamous cell carcinoma arising in the cerebellopontine angle. A 52-year-old man presented with left facial paralysis and cerebellar ataxia. He had undergone total removal of a benign epidermoid cyst six months previously. Postoperative magnetic resonance imaging of the brain revealed a heterogeneous and cystic lesion in the left cerebellopontine angle with hydrocephalus. The cyst wall was enhanced by gadolinium. He underwent ventricle-peritoneal shunt and removal again; the histopathological examination revealed a squamous cell carcinoma possibly arising from an underlying epidermoid cyst. This entity is being reported for its rarity. The presence of contrast enhancement at the site of an epidermoid cyst combined with an acute, progressive neurological deficit should alert the neurosurgeon to the possibility of a malignant transformation.

  20. Testicular cancer and intellectual disability

    Sasco, Annie,; Ah-Song, Roland; Nishi, Motoi; Culine, Stéphane; Réthoré, Marie-Odile; Satgé, Daniel

    2008-01-01

    The frequency of testicular cancer in men with intellectual disabilities is not precisely known, with the exception of some genetic conditions such as Down syndrome, where it has increased. Objective: To review systematically the literature through Pubmed with a particular focus on epidemiological studies of testicular cancer in persons with intellectual disability. Method: Literature review. Results: Testicular cancer was more frequent in subjects with intellectual disability than in the gen...

  1. Testicular biopsy in prepubertal boys

    Faure, Alice; Bouty, Aurore; O'Brien, Mike;

    2016-01-01

    No consensus exists regarding the precise role of testicular biopsy in prepubertal boys, although it is considered useful for assessing the potential consequences of undescended testes on fertility. Current scientific knowledge indicates that surgeons should broaden indications for this procedure...... preservation of fertility after gonadotoxic chemotherapy - even for prepubertal boys - are emerging. Cryopreservation of testicular tissue samples for the preservation of fertility - although still an experimental method at present - is appealing in this context. In our opinion, testicular biopsy in...

  2. Transverse testicular ectopia.

    Yıldız, Abdullah; Yiğiter, Murat; Oral, Akgün; Bakan, Vedat

    2014-02-01

    Described herein are six cases of transverse testicular ectopia. All patients who underwent orchidopexy at the one pediatric surgical unit between October 2001 and January 2008 were evaluated. The medical records of all patients diagnosed with transverse testicular ectopia were evaluated retrospectively. Five patients (84%) were admitted with a symptomatic right inguinal hernia and empty scrotum on the left side. Only one child (16%) had left-sided hernia and right non-palpable testis (age ranged from 1 month to 3 years). Four patients (66%) were diagnosed in the operating theatre and the last two (33%) on inguinal ultrasound preoperatively. Magnetic resonance imaging was also performed in the last patient. Herniorrhaphy with fixation of the ectopic gonad to the opposite hemiscrotum through a transseptal incision was performed in all patients. Postoperative complications were not observed. PMID:24548194

  3. Testicular neoplasm diagnosed by ultrasound.

    Senay, B A; Stein, B S

    1986-06-01

    The diagnosis of testicular cancer is usually made by the findings of a testicular mass on physical examination. In rare cases a young man will present with retroperitoneal nodes and a normal testicular examination. In such cases a testicular ultrasound may localize the testis which harbors a subclinical neoplasm. In addition serum markers of B-HCG and AFP are essential. As a screening procedure a urine pregnancy test is helpful, since it can be obtained quickly while quantitative B-HCG and APF results are delayed. PMID:3523046

  4. Mesotelioma Maligno Testicular

    Antonio Lara Torrico

    2011-06-01

    Full Text Available El mesotelioma maligno es un tumor adenomatoide de la línea de células no germinales, una neoplasia testicular muy rara, tan solo unos 100 casos han sido reportados en la literatura y la mayoría de los pacientes con este problema son mayores de 50 años. Más del 50% tienen el antecedente de exposición a los asbestos. Todos los pacientes con sospecha de un tumor maligno testicular deben someterse a una orquiectomía radical para evitarrecidivas. Presentamos el caso clínico de un paciente de sexo masculino de 69 años de edad que acudió a consulta con un cuadro de 6 meses de evolución con aumento de volumen del escroto izquierdo y drenaje de líquido serohemático a través de un orificio fistuloso. Al paciente se le realizó el tratamiento quirúrgico mediante orquiectomía radical más hemiescrotectomía izquierda y finalmente el examen histopatológico evidenció un mesotelioma maligno testicular mixto.

  5. Leech therapy for epidermoid cysts and review of the literature

    Abbas Rasi; Alireza Faghihi; Mirhadi Aziz Jalali; Abbas Zamanian; Gholamhossein Ghaffarpour

    2014-01-01

    Hirudo medicinalis sucks blood directly through the external mammalian skin. We recently observed a healthy 64-year-old Iranian man, who presented with numerous asymptomatic multilobular oval-to-round well-defined 0.5 to 1.5 cm cystic lesions with central umbilication (central black eschar) over the upper portion of his chest. We made the diagnosis of epidermoid cyst, giant comedone and leech bite on the basis of the constellation of clinical features. The patient was treated with oral ciprof...

  6. Isodense epidermoid cyst in the pineal region. Case report

    Yamanouchi, Yasuo; Takahara, Nobuhiko; Kawamura, Yasuo; Matsumura, Hiroshi

    1985-02-01

    A 69-year-old male was admitted complaining of gait disturbances and diplopia, 2.5 years after an episode of serous meningitis. Neurological examination on admission disclosed Parinaud's sign, unsteady gait and dysdiadochokinesis on the left side. A striking finding on the computerized tomography (CT) was the left to right shift of the posterior portion of the third ventricle without visualization of the quadrigeminal and ambient cisterns, which were almost completely occupied by an isodense mass accompanied by high dense flecks and a low dense part. Enhanced CT showed positive enhancement in the vicinity of the pineal calcification. By the suboccipital supracerebellar approach, an encapsulated mass containing brownish yellow fluid was subtotally removed and a histological examination of it revealed epidermoid tissue and hemosiderin deposits in the solid portion. Few reports of isodense epidermoid cysts have so far been found in the literature giving a full explanation for this unusual CT attenuation value. Based on the clinical course and histology of this case, the pathogenesis of the unusual density is discussed along the following lines: The mixture of the low dense factor due to cholesterin and the high dense factor due to prior bleeding is believed to result in the isodense attenuation value in the liquid portion. Also, in the solid part, a microscopically mixed texture of deposited hemosiderin and cholesterin clefts in the inflammatory granulomatous tissue could explain its density on the CT scan.

  7. Epidermoid gastric cancer review literature a case study

    Full text: introduction. epidermoid epidemiologic ally gastric cancer etiology is extremely uncommon forming a 0.04 to 0.07% of cases. target. reviewing the literature from a clinical case of a female patient 60 years epidermoid carrier loco regionally advanced gastric cancer. methodology and methods. analyze the case of gastric cancer squamous which TB diagnosed n2 m0 be a eiiic. results. the case was presented as an atypical dyspepsia was diagnosed with cancer gastric squamous after taking multiple biopsies. diagnosis is confirmed and the checked laparoscopically resectable liver infiltration, commitment vascular and pancreatic seen by ct scan. it was decided to establish treatment palliative chemotherapy based on docetaxel, 5-fluorouracil and cisplatin that fails to receive and who dies of massive haematemesis. conclusions. it is well established the pathogenesis of this disease. in series reported we found a higher incidence in males, with a median age presentation at age 64. the most common is the fun dus and diagnosis in advanced stages is most prevalent. being a rare histological subtype as there is no evidence to support a massed different therapeutic adenocarcinoma

  8. A case of a spontaneously ruptured epidermoid cyst

    Intracranial fat-containing congenital tumors are characterized by negative absorption values on CT. We hereby report a case of an epidermoid cyst with subarachnoid free fats diagnosed preoperatively by CT. A 21-year-old female was admitted to our hospital because of continuous mild headache and nausea. At the time of admission, the results of her physical and neurological examinations were normal. CT, however, demonstrated multiple subarachnoid low-density spots and a suprasellar low-density area with high-density spots. In addition, there were negative absorption values (-12 ∼ -77), suggesting free fats. A spontaneously ruptured epidermoid or dermoid cyst was diagnosed on the basis of these findings. At surgery, a suprasellar tumor containing a yellowish, cheese-like material was confirmed. The patient made an uneventful recovery and was discharged 14 days after surgery. There have been several published reports of CT appearances of intracranial fat-containing tumors. However, spontaneously ruptured cases diagnosed by CT are rare. CT was found to be useful for the diagnosis of spontaneously ruptured cases of fat-containing tumors. (author)

  9. Cytodiagnosis of epidermoid cyst of the upper lip: A common lesion in an uncommon site

    Jyoti Prakash Phukan

    2014-01-01

    Full Text Available Epidermoid cyst and dermoid cysts are developmental pathologies thought to derive from aberrant ectodermal tissue. They are uncommon in the head and neck region. Rarely, they can be found in the oral cavity and buccal mucosa. However, epidermoid cyst is extremely uncommon in the upper lip and is rarely reported. In this study, we report an uncommon case of epidermoid cyst occurring in the upper lip diagnosed by fine-needle aspiration cytology (FNAC. We present this case because of its extremely rare site of presentation and also to highlight the role of FNAC to in the pre-operative diagnosis of this benign lesion.

  10. Dorsal intramedullary spinal epidermoid cysts: Report of two cases and review of literature

    Cincu Rafael

    2007-01-01

    Full Text Available Intramedullary epidermoid cysts of the spinal cord are rare tumors, especially those not associated with spinal dysraphism. About 50 cases have been reported in the literature. Of these, only seven cases have had magnetic resonance imaging (MRI studies. We report two cases of spinal intramedullary epidermoid cysts with MR imaging. Both were not associated with spina bifida. In one patient, the tumor was located at D4 vertebral level; while in the other, within the conus medullaris. The clinical features, MRI characteristics and surgical treatment of intramedullary epidermoid cyst are presented with relevant review of the literature.

  11. Epidermoid cyst of the floor of the mouth. A case report and literature review

    Rojas-Madrigal A

    2012-02-01

    Full Text Available Dermoid and epidermoid cysts are cystic benign, slightly common malformations that may be found in the area of head and neck between 1.6 and 7 %, representing less than 0.01 % of all the cysts of the oral cavity. This pathology is important of the knowledge of the professional in dentistry and medicine to be able to do the early diagnose and the respective treatment. The purpose of this study is the review of the relevant literature of the dermoid and epidermoid cysts and the presentation of a case of epidermoid cyst in floor of mouth in a patient of 13 years and 5 months of age.

  12. Epidermoid carcinoma of the conjunctiva. Case report Carcinoma epidermoide de conjuntiva. Presentación de un caso

    María Adela LLull Tombo

    2011-12-01

    Full Text Available

    The case of a 76 years old male patient with a conjunctival squamous cell carcinoma is presented. The main clinical manifestation was discomfort, pain and redness in the eye. Physical ocular examination revealed a whitish eye injury, with blood vessels in the inner corner, above the right eye pterygium. It was diagnosed as squamous cell carcinoma, which evolved rapidly and invasively. Due to recurrences, three surgeries were performed.

    Se presenta el caso de un paciente de 76 años de edad con un carcinoma epidermoide de conjuntiva.  La manifestación clínica principal fue la molestia, el dolor y el ojo rojo. Al examen físico ocular se encontró lesión blanquecina, con vasos sanguíneos en el ángulo interno, por encima del pterigion en ojo derecho. Se diagnosticó como carcinoma epidermoide de la conjuntiva, el cual evolucionó de forma rápida e invasiva. Se intervino quirúrgicamente en tres ocasiones debido a las recurrencias.

  13. Testicular Feminization Syndrome

    Vaneet Kour, Ajay Abrol

    2005-01-01

    Full Text Available Testicular feminization syndrome or androgen insensitivity syndrome is a rare disorder with anincidence of 1:20,000-64,000 male births. The individual with complete form of this syndrome (CIAShave female external genitalia while those with partial form (PIAS have variable ambiguity ofgenitalia and often need extensive reconsructive surgery. The diagonosis should be suspected infemale child with inguinal hernia or presenting with primary ammenorrohea and on examinationthere is no vagina with absent axillary or pubic hair. Awareness of this entity is important as withearly diagonosis such disorder can be managed appropriately and accurate information can begiven to parents regarding long term issues of harmone replacement therapy and fertility.

  14. Studies of testicular function after treatment for testicular tumor, 1

    Recently, the treatment for testicular tumor has improved. Preservation of testicular function in the treatment of testicular tumor is important, because the majority of the patients are young. We investigated the testicular function of patients with testicular tumor before, during and after treatment. As a part of this study, the fertility of patients with testicular tumor before and after treatment was evaluated. 1. Fourteen of 78 married patients (18 %) showed sterility for two or more years before treatment. 2. When semen was examined in 31 patients before treatment, only seven patients (23 %) showed normal sperm counts of more than 40 x 106/ml, and 19 (61.3 %) showed oligospermia or azoospermia with sperm counts of less than 10 x 106/ml. 3. Of 20 patients who underwent retroperitoneal lymphnode dissection, 15 developed ejaculation deficiency. Four other patients also developed ejaculation deficiency but recovered, and three of them rendered their wives pregnant. 4. Of 23 patients given radiotherapy, nine produced children both before and after treatment, nine produced children before treatment but showed sterility after treatment, and five showed sterility both before and after treatment. 5. Examination of semen was performed in 17 patients given radiotherapy and in five given chemotherapy. Many patients developed oligospermia or azoospermia after the treatments, but revealed a tendency to recover with time. Based on the results mentioned above, it is inferred that the ability to produce sperm in patients with testicular tumor after treatment decreases but the decrease tends to recover to normal with time. (author)

  15. TESTICULAR FEMINISING SYNDROME

    Vijay Kumar

    2014-03-01

    Full Text Available Testicular feminization syndrome is a form of pseudohermaphroditism where phenotypic female has male gonads and is genotypically male. Androgen insensitivity syndrome (AIS, also known as testicular feminization, encompasses a wide range of phenotypes that are caused by numerous different mutations in the androgen receptor gene. AIS is an X-linked recessive disorder that is classified as complete, partial based on the phenotypic presentation. The clinical findings include a female type of external genitalia, 46-XY karyotype, absence of Mullerian structures, presence of Wolffian structures to various degrees, and normal to high testosterone and gonadotropin levels. The syndrome is illustrated by a 24-year-old phenotypic female who presented with a primary amenorrhea, female-type external genitalia, an absent uterus and ovaries, and bilateral testes at the level of the internal inguinal ring. Management includes counseling, gonadectomy to prevent primary malignancy in undescended gonad, and hormone replacement. The karyotyping of family members is advocated because of known familial tendencies.

  16. Testicular cytology in azoospermia

    Usha Prasad

    2015-06-01

    Results: The commonest group with infertility were in the age group 21-30 years. The testicular size was normal in 87.17% of subjects and 12.82% had small testis. Out of 39 subjects with azoospermia 38.46% subjects had varicocele. Varicocele was commonly associated with duct obstruction. The commonest causes observed in cases with azoospermia were; hypospermatogenesis with maturation arrest (4/39,10.25%, duct obstruction (12/39,30.76%, maturation arrest (7/39,17.94%, testicular atrophy (10/39,25.64% and sertoli cell only syndrome (2/39,5.12%. In the present study diagnostic accuracy was 89.18%. Conclusions: Fine needle aspiration cytology is as informative as biopsy and can be done as a routine procedure. It helps us in ruling out obstructive and non-obstructive causes for azoospermia. In cases where FNAC shows normal spermatogenesis with azoospermia, biopsy and Doppler study is indicated to rule out duct obstruction which can be corrected surgically. It is a simple and cost effective. [Int J Reprod Contracept Obstet Gynecol 2015; 4(3.000: 647-652

  17. Intranasal epidermoid cyst causing upper airway obstruction in three brachycephalic dogs.

    Murgia, D; Pivetta, M; Bowlt, K; Volmer, C; Holloway, A; Dennis, R

    2014-08-01

    This case report describes three brachycephalic dogs with intranasal epidermoid cysts that were causing additional upper airway obstruction. Although epidermoid cysts have been described in several locations in dogs, to the authors' knowledge intranasal epidermoid cysts have not been previously reported. All dogs had mucopurulent to haemorrhagic nasal discharge. Magnetic resonance imaging of the head revealed the presence of unilateral or bilateral intranasal cystic lesions obstructing the nasal cavities partially or completely, with atrophy of the ipsilateral nasal turbinates. The cystic lesions were surgically excised in all dogs using a modified lateral alveolar mucosal approach to the affected nasal cavity. Aerobic, anaerobic and fungal culture of the cystic contents were negative and histology of the excised tissue was consistent with a benign intranasal epidermoid cyst in each dog. Upper airway obstruction was clinically improved in two dogs. PMID:24697627

  18. Epidermoid cyst radiologically mistaken as a left sided subpulmonic effusion.

    Sameh, Ibrahim Sersar; Gewaeli, NourEldeen Noaman; Hamza, Usama Ali; Awadalla, Mohammed Mounir el-said

    2003-09-01

    A 33-year-old female had a left sided chest pain for the last 3 months. Chest X-ray showed a left basal opacity. Computed tomography chest suggested a left sided subpulmonic effusion (17.5x12.2x13 cm) with thick enhanced walls with marked collapse of the left lower lobe and displacement of the heart and mediastinum to the right side. Trial of thoracocentesis was done and it was positive. Trial of intercostal tube insertion was done with a sense of very thick pleura and the patient developed a vasovagal attack. Accordingly, exploratory thoracotomy was decided. Intraoperative assessment showed a huge anterosuperior mediastinal cyst attached to the pericardium and was successfully resected. The pathological findings were compatible with epidermoid cyst. PMID:17670071

  19. Perspectives for the treatment of epidermoid oesophageal cancer

    Prior to the eighties, most patients with a diagnosis of epidermoid oesophageal cancer only received palliative symptomatic care. To date, most all undergo either surgery or medical treatment or both. Late diagnosis due to lack of clinical signs in the early phases of the disease, and perhaps insufficient attempts at identifying patients at risk who could benefit from systematic screening, is still an important problem although the number of diagnosed cases continues to rise (from 104 in 1985 to 151 in 1989 in Finistere in western France). Two different therapeutic attitudes could improve the prognosis: extensive surgery as proposed by the Japanese with dissection of all invaded lymph nodes whatever the localization and a multimodal approach combining radiochemotherapy and surgery. Although outcome can apparently be improved in certain types of oesophageal cancer, the proposal of aggressive extensive dissection could have an effect on respiratory complications and would not necessarily be adapted to the risk involved in western patients. Certain teams have nevertheless taken this route and will soon report their results. In France two phase II trials combining radiotherapy, chemotherapy (cisplatinium) and surgery have reported encouraging results with complete sterilization in 24% of the cases and 50% survival at 18 months. In our own series of 68 patients, we have obtained 41% sterilization and 56,3% survival at 3 years with the multi-modal protocol. The high number on non-responders to chemotherapy emphasizes the importance of maintaining surgical resection whenever possible. The discouraging reports published before 1980 have been contradicted by improvements in outcome achieved over the last decade. Today, all patients with a diagnosis of epidermoid cancer of the oesophagus should benefit from either palliative or curative care based on the latest advances in radiotherapy, chemotherapy and surgery. (author). 10 refs

  20. Retrorectal epidermoid cyst with unusually elevated serum SCC level, initially diagnosed as an ovarian tumor

    Noriyuki Inaba; Kazumi Tada; Ichio Fukasawa; Nobuaki Kosaka; Akiko Shoda; Keiichi Kubota; Hitoshi Nagata; Takahiro Fujimori; Shigeki Tomita; Masaru Hayashi

    2009-01-01

    Retrorectal epidermoid cyst is one of the developmental cysts which arise from remnants of embryonic tissues. We report a rare case of retrorectal epidermoid cyst, initially diagnosed as an ovarian tumor. Serum SCC value as tumor marker was elevated to the high level. Laparoscopy revealed ovaries, uterus and other pelvic organs were all normal. This tumor existed in the retroperitoneal cavity and compressed the rectum. Later, complete tumor resection was performed by laparotomy. Histological ...

  1. Epidermoid cyst of the coronal sulcus mimicking penile cancer: a case report

    Cormio, Luigi; Mancini, Vito; Sanguedolce, Francesca; Massenio, Paolo; Fucci, Livia; Bufo, Pantaleo; Traficante, Antonio; Carrieri, Giuseppe

    2014-01-01

    Introduction Epidermoid cysts represent common benign tumors occurring anywhere in the body but very rarely in the penis. Only a few cases of penile localization have been reported in the literature so far, most of them being congenital and/or idiopathic, usually presenting in children as slow-growing, solitary, well-delimited cystic lesions. Here, we describe the case of a patient with a penile epidermoid cyst presenting as an ulcerated lesion of the coronal sulcus, thus mimicking penile can...

  2. Quiste óseo simple atípico: Presentación de un caso clínico Atypical Simple Bone Cyst: A Case Report

    L.R González

    2009-02-01

    Full Text Available El quiste óseo simple (sinonimia quiste óseo traumático, quiste óseo solitario, quiste óseo hemorrágico es un pseudoquiste intraóseo desprovisto de recubrimiento epitelial con un contenido seroso y/o hemático que en ocasiones puede estar ausente. Es una patología poco frecuente que afecta a los huesos maxilares con predilección por el maxilar inferior. El objetivo del presente trabajo es presentar un caso de quiste óseo simple en maxilar inferior que difiere de los habitualmente encontrados en los huesos maxilares en cuanto a su presentación clínica, radiográfica e histopatológica.The simple bone cyst (reported in the literature as traumatic bone cyst, solitary bone cyst, hemorrhagic bone cyst is an intraosseous pseudocyst devoid of epithelial lining and filled with serous and/or hematic fluid that may also be lacking. Is a an uncommon condition that usually affects the jaws, with predilection for the lower jaw. The aim of the present work was to report a case of traumatic bone cyst of the jaw that differs from other maxillary bone cysts in its clinical, radiologic, and histologic presentation.

  3. Differentiation between pediatric spinal arachnoid and epidermoid-dermoid cysts: is diffusion-weighted MRI useful?

    Appropriate differentiation between epidermoid-dermoid and arachnoid cysts is important for patient management. MRI has had limitations in differentiating these two types of cysts, especially in the region of the spinal cord. To evaluate the role of diffusion-weighted (DW) MRI for differentiation between spinal arachnoid and epidermoid-dermoid cysts. Four children underwent conventional and DW MRI. Turbo spin-echo imaging was used to obtain DW images. On conventional MRI, low T1-W and high T2-W signal was present in all lesions. DW imaging showed restricted diffusion in two patients with epidermoid-dermoid cysts and no water restriction in two patients with arachnoid cysts. Three of four children had extramedullary lesions and one patient had an intramedullary lesion. Three children had surgery, two with epidermoid-dermoid cysts and one with arachnoid cyst. Diagnosis was confirmed by histopathology. One child with a thoracic arachnoid cyst had stable clinical imaging findings during a follow-up of 21 months. On conventional MRI, epidermoid-dermoid and arachnoid cysts have similar signal characteristics. Initial experience with spine DW imaging shows promise in differentiating epidermoid-dermoid cysts from arachnoid cysts. Preoperative differentiation is important because it changes management and surgical approach. (orig.)

  4. Differentiation between pediatric spinal arachnoid and epidermoid-dermoid cysts: is diffusion-weighted MRI useful?

    Kukreja, Kamlesh [Miami Children' s Hospital, Department of Radiology, Miami, FL (United States); Manzano, Glen; Ragheb, John [Miami Children' s Hospital and University of Miami, Department of Neurological Surgery, Miami, FL (United States); Santiago Medina, L. [Miami Children' s Hospital, Health Outcomes, Policy and Economics (HOPE) Center, Department of Radiology, Miami, FL (United States)

    2007-06-15

    Appropriate differentiation between epidermoid-dermoid and arachnoid cysts is important for patient management. MRI has had limitations in differentiating these two types of cysts, especially in the region of the spinal cord. To evaluate the role of diffusion-weighted (DW) MRI for differentiation between spinal arachnoid and epidermoid-dermoid cysts. Four children underwent conventional and DW MRI. Turbo spin-echo imaging was used to obtain DW images. On conventional MRI, low T1-W and high T2-W signal was present in all lesions. DW imaging showed restricted diffusion in two patients with epidermoid-dermoid cysts and no water restriction in two patients with arachnoid cysts. Three of four children had extramedullary lesions and one patient had an intramedullary lesion. Three children had surgery, two with epidermoid-dermoid cysts and one with arachnoid cyst. Diagnosis was confirmed by histopathology. One child with a thoracic arachnoid cyst had stable clinical imaging findings during a follow-up of 21 months. On conventional MRI, epidermoid-dermoid and arachnoid cysts have similar signal characteristics. Initial experience with spine DW imaging shows promise in differentiating epidermoid-dermoid cysts from arachnoid cysts. Preoperative differentiation is important because it changes management and surgical approach. (orig.)

  5. Diffusion tensor mode in imaging of intracranial epidermoid cysts: one step ahead of fractional anisotropy

    The signal characteristics of an epidermoid on T2-weighted imaging have been attributed to the presence of increased water content within the tumor. In this study, we explore the utility of diffusion tensor imaging (DTI) and diffusion tensor metrics (DTM) in knowing the microstructural anatomy of epidermoid cysts. DTI was performed in ten patients with epidermoid cysts. Directionally averaged mean diffusivity (Dav), exponential diffusion, and DTM-like fractional anisotropy (FA), diffusion tensor mode (mode), linear (CL), planar (CP), and spherical (CS) anisotropy were measured from the tumor as well as from the normal-looking white matter. Epidermoid cysts showed high FA. However, Dav and exponential diffusion values did not show any restriction of diffusion. Diffusion tensor mode values were near -1, and CP values were high within the tumor. This suggested preferential diffusion of water molecules along a two-dimensional geometry (plane) in epidermoid cysts, which could be attributed to the parallel-layered arrangement of keratin filaments and flakes within these tumors. Thus, advanced imaging modalities like DTI with DTM can provide information regarding the microstructural anatomy of the epidermoid cysts. (orig.)

  6. What's New in Testicular Cancer Research and Treatment?

    ... resources for testicular cancer What’s new in testicular cancer research and treatment? Important research into testicular cancer is ... Your Doctor After Treatment What`s New in Testicular Cancer Research? Other Resources and References Cancer Information Cancer Basics ...

  7. How Is Testicular Cancer Diagnosed?

    ... proteins called tumor markers , such as alpha-fetoprotein (AFP) and human chorionic gonadotropin (HCG). When these tumor ... that there is a testicular tumor. Rises in AFP or HCG can also help doctors tell which ...

  8. General Information about Testicular Cancer

    ... are used to detect testicular cancer: Alpha-fetoprotein (AFP). Beta-human chorionic gonadotropin (β-hCG). Tumor marker ... places in the body, and blood levels of AFP, β-hCG, and LDH). Type of cancer. Size ...

  9. Treatment Option Overview (Testicular Cancer)

    ... and nonseminomas . These 2 types grow and spread differently and are treated differently. Nonseminomas tend to grow and spread more quickly ... trials is available from the NCI website . To Learn More About Testicular Cancer For more information from ...

  10. Impacto de la dieta sobre la inducción de infección con quistes de Giardia lamblia en ratas Sprague-Dawley

    Díaz-Cinco Martha Elvia

    2002-01-01

    Full Text Available Objetivo. Evaluar el efecto de la desnutrición en la inducción de la giardiosis con diferentes concentraciones de quistes de Giardia lamblia utilizando como modelo animal ratas Sprague-Dawley. Material y métodos. Es un estudio experimental efectuado entre 1995 y 1999, en el Centro de Investigación en Alimentación y Desarrollo, de la ciudad de Hermosillo, estado de Sonora, México, y cuya muestra estuvo integrada por dos grupos de 6 a 8 unidades experimentales, las cuales recibieron dos tipos de dieta y cinco tratamientos con diferente concentración de inóculo de quistes de Giardia lamblia. Durante la fase experimental se monitoreó la excreción de quistes, ganancia de peso, consumo de alimento, análisis del contenido intestinal y daños macro y microscópicos en mucosa intestinal. El tratamiento estadístico de los datos consistió en análisis de varianza, y de residuales cuando fue necesario. Resultados. En los animales alimentados con una dieta que cubre sus requerimientos nutricionales (DN se observó que es posible provocar la infección con 60 quistes, mientras que en los animales desnutridos (dieta DLN la concentración que se requiere es de únicamente seis quistes para establecer daños a nivel de mucosa intestinal. Conclusiones. La ganancia de peso monitoreada durante los 10 días de ensayo no resultó ser un buen indicador de la infección por Giardia lamblia. El porcentaje de infección depende de la concentración de quistes inoculados y del estado de nutrición de los animales evaluados.

  11. Association between testicular microlithiasis, testicular cancer, cryptorchidism and history of ascending testis

    Stamatiou Konstantinos

    2006-08-01

    Full Text Available OBJECTIVE: To prospectively determine the prevalence of testicular microlithiasis in symptomatic patients who were referred for scrotal ultrasound examination and to evaluate the possible association of testicular microlithiasis with testicular cancer and other conditions such as cryptorchidism or history of ascending testis. MATERIALS AND METHODS: 391 men who were referred to our institutions between July 2002 and May 2005 for any type of symptoms from the testicles, underwent physical and scrotal ultrasound examination. The presence of testicular microlithiasis, the number of lesions and the involvement of both testicles in relation to the symptoms as well as the coexistence of other lesions were studied. RESULTS: Eighteen (4.6% of 391 men enrolled into the study had testicular microlithiasis. Two out of the eighteen patients (11% had concomitant testicular cancer, which was confirmed by pathological evaluation of the orchidectomy specimen. One of the patients with testicular microlithiasis presented a rising in biochemical tumor markers (LDH, and HCG and underwent orchidectomy one year later. Five of the remaining 373 (1.3% patients without microlithiasis were diagnosed with testicular cancer. Thirty six men reported having a history of ascending testis, but none of them was found with testicular cancer. Two cases of testicular torsion in a cryptorchid position had testicular microlithiasis, but the orchidectomy specimen (after surgery was negative for testicular cancer. The correlation between testicular cancer and testicular microlithiasis found in our study was statistically significant (p < 0.05. CONCLUSION: There seems to be an association between testicular microlithiasis and testicular cancer.

  12. Reconstrucción de defectos óseos causados por quistes residuales de los maxilares con hidroxiapatita porosa coralina hap-200

    Juan Carlos Quintana-Díaz; Ramón González-Santos; Mayrim Quintana-Giralt

    2014-01-01

    Se presentan los resultados obtenidos como parte de la extensión de las aplicaciones clínicas de la Hidr oxiapatita Coralina ® HAP - 200 como biomaterial de implante para la regeneración del tejido óseo en la región maxilofacial. En este caso, se emplea en forma de gránulos para la restauración de defectos óseos causados por quistes residuales a 24 pacientes (17 2 quistes) siguiendo las indicaciones y normas establecidas para el uso de este tipo de material. La evaluación clínica y radiográfi...

  13. Studies of testicular function after treatment for testicular tumor, 2

    It is important to preserve the testicular function of patients with testicular tumor after treatment. Testicular function after radiotherapy was endocrinologically investigated in the present study. 1. The levels of LH, FSH and testosterone in the blood were sequentially determined in patients with testicular tumor before, during and after radiotherapy. The blood levels of LH and FSH were high after therapy in the majority of the cases, but the levels decrease concomitantly with time. Blood levels of testosterone remained within the normal range. 2. The Gn-RH stimulation test after radiotherapy revealed an abnormally high response and a delayed normalization of the LH level within three years after therapy. However, these changes showed a tendancy to normalize in the patients after therapy for three years or longer. 3. The hCG stimulation test was performed after radiotherapy. The reaction rate of hCG was low in patients within three years on therapy, whereas it tended to return to normal pattern after three or more years on therapy. The results lead the conclusion as follows. 1. Spermatogenesis was damaged in the majority of testicular tumor after radiotherapy. However, it was recovered to a normal spermatogenesis after cessation of the therapy. 2. From the high basal level of serum LH and the response to Gn-RH and hCG stimulation tests after radiotherapy, it is presumed that the reserve function of Leydig cell was impaired by radiotherapy, although it returns to normal status after three years on the therapy. (author)

  14. Radiotherapy of testicular tumours

    Schumacher, M.

    1980-01-01

    In the first part of the paper, the general pathological, diagnostical and therapeutical measures against seminomas and teratomas are dealt with. In the second part, the results obtained by the radiotherapeutical division of the University Clinics of Freiburg 1964-1977 in the treatment of seminomas and teratomas are described. The average age of the 59 seminoma patients was 36 years, the average age of the 28 teratoma patients was 26. The 5-years-total survival rate of the seminoma patients was 80.8%, for teratoma patients it was 30.5%. In the individual phases, of all seminoma patients in stage I, 93.1% were still alive after 5 years, in stage II 95.9%, in stage III 12.5%. The 5-years survival rate of the teratoma patients in stage I was around 100%, in stage II around 36.8% and in stage III around 20.5%. In the discussion, the problems of the histological and pathological classification for testicular tumours are talked about and the treatment methods used at the Freiburg university clinics are described. The results obtained in the Freiburg university clinics are compared with those of other authors.

  15. Radiografía periapical como herramienta en el diagnóstico y tratamiento de quiste periapical

    J. Verbel Bohórquez; J. Ramos Manotas; A. Díaz Caballero

    2015-01-01

    Introducción: El quiste periapical es una lesión inflamatoria común de los maxilares, que al alcanzar un tamaño significativo, causa deformidad del hueso afectado, retención o incluso el desplazamiento de dientes adyacentes. Se presentó caso de paciente que acudió a consulta odontológica, por presencia de sintomatología dolorosa durante el consumo de alimentos. Al examen clínico se observó encía adherida con presencia de inflamación y enrojecimiento a nivel de órgano dentario 14; radiográfica...

  16. Limitaciones de la tomografia axial computada en la localizacion de quistes hidatidicos abdominales en pacientes con confirmacion inmunodiagnostica

    Guarnera, E A; V. M. Varela-Díaz

    1984-01-01

    Se describe el aporte de la prueba de doble disfusión arco 5 (DD5) al diagnóstico de la hidatidosis en dos pacientes con operaciones previas. En una de ellas, asintomática, la reacción positiva a los cinco años de su última intervención quirúrgica por hidatidosis, permitió diagnosticar la presencia de quistes cuya localización abdominal fue establecida por la tomografía axial computada (TAC). En el otro caso, sintomático, aunque operado de hidatidosis nueve años antes, la positividad a la DD5...

  17. Primary Testicular B-cell Lymphoma

    Aykut Buğra Şentürk; Musa Ekici; Hamit Ersoy

    2015-01-01

    Primary testicular lymphoma constitutes only 1-7% of all testicular neoplasms and less than 1% of all non-Hodgkin lymphoma. We report a 69-year-old man who presented with a painful right testicular mass. Treatment modalities consist of surgical excision, chemotherapy and radiation therapy, however there are no standardized treatment options.

  18. Primary Testicular B-cell Lymphoma

    Aykut Buğra Şentürk

    2015-12-01

    Full Text Available Primary testicular lymphoma constitutes only 1-7% of all testicular neoplasms and less than 1% of all non-Hodgkin lymphoma. We report a 69-year-old man who presented with a painful right testicular mass. Treatment modalities consist of surgical excision, chemotherapy and radiation therapy, however there are no standardized treatment options.

  19. 21 CFR 876.3750 - Testicular prosthesis.

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Testicular prosthesis. 876.3750 Section 876.3750...) MEDICAL DEVICES GASTROENTEROLOGY-UROLOGY DEVICES Prosthetic Devices § 876.3750 Testicular prosthesis. (a) Identification. A testicular prosthesis is an implanted device that consists of a solid or gel-filled...

  20. Fractura patológica de la mandíbula asociada a quiste radicular: Reporte de 3 casos clínicos Mandibular pathologic fracture associated with radicular cyst: Report of three clinical cases

    J. Bouguila; L. Córdova Jara; I. Zairi; A. Adouani

    2008-01-01

    Introducción. El quiste radicular es el quiste más común de los maxilares. Su tamaño puede variar desde una lesión que abarca el proceso alveolar hasta uno extenso que oblitera el espacio antral maxilar o causa una fractura patológica mandibular. Reporte de casos. Se reportan tres casos con fractura patológica mandibular asociados a quiste radicular ocurridos después de trauma facial. El diagnóstico fue sugerido por un estudio clínico, radiografía panorámica y confirmado por el estudio histop...

  1. Quiste cervical como manifestación inicial de un microcarcinoma papilar de tiroides

    Jorge Fallas González

    2012-03-01

    Full Text Available Las masas quísticas en cuello son usualmente benignas en pacientes jóvenes. Sin embargo, tumores malignos de la cabeza y el cuello pueden presentarse ocasionalmente con metástasis quísticas. Se presenta el caso de una paciente de 33 años asintomática con una masa cervical quística de gran tamaño con 1 año de evolución, que inicialmente fue manejada como un quiste branquial, en quien luego de estudios por imagen e histopatológicos se sospechó carcinoma papilar de tiroides. Este diagnóstico fue corroborado en el trans-operatorio y se trató con tiroidectomía total, disección ganglionar del compartimiento central y disección ganglionar radical modificada derecha. El diagnóstico definitivo en el espécimen quirúrgico fue de un microcarcinoma papilar de tiroides con metástasis ganglionares quísticas y posteriormente la paciente recibió terapia con yodo radioactivoCystic cervical masses are usually benign in the young adult population. However malignant tumors of the head and neck may present ocasionally as cystic metastasis. Herein we report a case of a 33 year old female patient, asymptomatic, with a huge cystic cervical mass of 1 year data. The initial diagnosis was a branchial clef cyst, but after imaging studies and histopathologic examination papillary thyroid carcinoma was suspected. This diagnosis was confirmed in an intraoperatory consultation, so a total thyroidectomy, central lymph node dissection and modified radical neck dissection was performed. The final diagnosis on the surgical specimen was a papillary microcarcinoma of the thyroid with cystic lymph node metastasis and the patient received radioactive iodine afterwards

  2. Primary intradural sacral epidermoid in a nondysraphic spine: Case report and review of literature

    Sivaraju, Laxminadh; Thakar, Sumit; Ghosal, Nandita; Hegde, Alangar S

    2016-01-01

    The occurrence of epidermoids within the spinal canal is uncommon. Most of the reported spinal epidermoids (SEs) have been described in the thoracic or lumbar regions. They occur either following trauma or in the setting of coexistent spinal dysraphism. The authors describe an unusual case of a 28-year-old lady who presented with long-standing back pain and urinary incontinence. Magnetic resonance imaging (MRI) of her spine demonstrated a sacral SE without any coexistent spinal dysraphism. The diagnosis of an epidermoid was confirmed by histopathological examination following laminectomy and excision. To the authors’ best knowledge, this is the third case of a sacral SE occurring in a non-dysraphic spine. The case is discussed in the light of a relevant literature review.

  3. Quiste globulomaxilar de localización inusual: Reporte de un caso An unusual case of globulomaxillary cyst: a case report

    J. Orozco Ariza

    2009-12-01

    Full Text Available El quiste globulomaxilar es un quiste no odontogénico localizado entre el incisivo lateral y canino del maxilar superior, radiográficamente aparece como una lesión radiolúcida unilocular que desplaza las mencionadas piezas dentarias mostrando una imagen de pera invertida característico de la lesión cuya lámina dura es continua y raras veces interrumpida. La valoración clínica radiográfica es importante para plantear en el diagnóstico diferencial la probable presencia del quiste globulomaxilar. La muestra anatomopatológica debe ser remitida íntegramente para su estudio y diagnóstico definitivo demostrando la presencia de tejido epitelial. Se presenta caso clínico de quiste globulomaxilar en un paciente femenino de 19 años de edad localizado entre canino y primer premolar superior izquierdo.Globulomaxillary cyst is a nonodontogenic cyst usually located between maxillary lateral incisor and canine. Radiographic images appears like an unilocular radiolucent lesion that displaced dental teeth showing a invert pear image characteristic of the lesion. X ray and clinical examinations are important to establish the differential diagnosis of globulomaxillary cyst. The hystological examination must be send to its study and definitive diagnoses showing the presence of epithelial tissue. A clinical case of globulomaxillary cyst is presented in a 19 -year- old female patient located between canine and left first premolar maxillary region.

  4. Histological evidence of testicular dysgenesis in contralateral biopsies from 218 patients with testicular germ cell cancer

    Hoei-Hansen, Christina E; Holm, Mette; Rajpert-De Meyts, Ewa;

    2003-01-01

    This study was prompted by a hypothesis that testicular germ cell cancer may be aetiologically linked to other male reproductive abnormalities as a part of the so-called 'testicular dysgenesis syndrome' (TDS). To corroborate the hypothesis of a common association of germ cell cancer with testicular...... presenting with testicular germ cell neoplasms of the adolescent and young type. The findings therefore support the hypothesis that this cancer is part of a testicular dysgenesis syndrome. The presence of contralateral carcinoma in situ was higher in the present study than previously reported....... dysgenesis, microscopic dysgenetic features were quantified in contralateral testicular biopsies in patients with a testicular germ cell tumour. Two hundred and eighty consecutive contralateral testicular biopsies from Danish patients with testicular cancer diagnosed in 1998-2001 were evaluated...

  5. Histological evidence of testicular dysgenesis in contralateral biopsies from 218 patients with testicular germ cell cancer

    Hoei-Hansen, Christina E; Holm, Mette; Rajpert-De Meyts, Ewa; Skakkebæk, Niels Erik

    2003-01-01

    This study was prompted by a hypothesis that testicular germ cell cancer may be aetiologically linked to other male reproductive abnormalities as a part of the so-called 'testicular dysgenesis syndrome' (TDS). To corroborate the hypothesis of a common association of germ cell cancer with testicular...... dysgenesis, microscopic dysgenetic features were quantified in contralateral testicular biopsies in patients with a testicular germ cell tumour. Two hundred and eighty consecutive contralateral testicular biopsies from Danish patients with testicular cancer diagnosed in 1998-2001 were evaluated...... presenting with testicular germ cell neoplasms of the adolescent and young type. The findings therefore support the hypothesis that this cancer is part of a testicular dysgenesis syndrome. The presence of contralateral carcinoma in situ was higher in the present study than previously reported....

  6. Testicular biopsy: clinical practice and interpretation

    Gert R Dohle; Saad Elzanaty; Niels J van Casteren

    2012-01-01

    Testicular biopsy was considered the cornerstone of male infertility diagnosis for many years in men with unexplained infertility and azoospermia.Recent guidelines for male infertility have limited the indications for a diagnostic testicular biopsy to the confirmation ofobstructive azoospermia in men with normal size testes and normal reproductive hormones.Nowadays,testicular biopsies are mainly performed for sperm harvesting in men with non-obstructive azoospermia,to be used for intracytoplasmic sperm injection.Testicular biopsy is also performed in men with risk factors for testicular malignancy.In a subgroup of infertile men,there is an increased risk for carcinoma in situ of the testis,especially in men with a history of cryptorchidism and testicular malignancy and in men with testicular atrophy.Ultrasonographic abnormalities,such as testicular microlithiasis,inhomogeneous parenchyma and lesions of the testes,further increase the risk of carcinoma in situ (CIS) in these men.For an accurate histological classification,proper tissue handling,fixation,preparation of the specimen and evaluation are needed.A standardized approach to testicular biopsy is recommended.In addition,approaches to the detection of CIS of the testis testicular immunohistochemistry are mandatory.In this mini-review,we describe the current indications for testicular biopsies in the diagnosis and management of male infertility.

  7. Giant Ovarian Cyst. A Case Report Quiste de ovario gigante. Presentación de un caso

    Yarisdey Corrales Hernández

    2012-09-01

    Full Text Available Ovarian cysts are common tumors among gynecological conditions. The case of a 46 years old woman who arrived at the Dr. Gustavo Aldereguía Lima General University Hospital in Cienfuegos, because of pain and swelling of the abdomen of a year of evolution is presented. The physical examination and ultrasound were performed and the patient was diagnosed with an ovarian dependant cystic mass. Laparotomy was performed and the left ovarian cyst was resected. In pathological and anatomical studies the diagnosis of an ovarian serous cystadenoma was confirmed.Los quistes de ovario son tumoraciones frecuentes en las afecciones ginecológicas. Se presenta el   caso de una paciente de 46 años de edad, que acudió al Hospital General Universitario Dr. Gustavo Aldereguía Lima, de Cienfuegos, refiriendo dolor y aumento de volumen del abdomen de un año de evolución. Se realizaron examenes físico y ultrasonográfico, mediante los que se le diagnosticó una masa quística dependiente de ovario. Se practicó laparotomía y se resecó un quiste de ovario izquierdo. En su estudio anatomopatológico se comprobó el diagnóstico de cistoadenoma seroso del ovario.

  8. Limitaciones de la tomografia axial computada en la localizacion de quistes hidatidicos abdominales en pacientes con confirmacion inmunodiagnostica

    E. A. Guarnera

    1984-12-01

    Full Text Available Se describe el aporte de la prueba de doble disfusión arco 5 (DD5 al diagnóstico de la hidatidosis en dos pacientes con operaciones previas. En una de ellas, asintomática, la reacción positiva a los cinco años de su última intervención quirúrgica por hidatidosis, permitió diagnosticar la presencia de quistes cuya localización abdominal fue establecida por la tomografía axial computada (TAC. En el otro caso, sintomático, aunque operado de hidatidosis nueve años antes, la positividad a la DD5 confirmó la etiología de la enfermedad que se había sospechado por centellografía, TAC y su historia clínica. En ambos casos, sin embargo, se hallaron en el acto quirúrgico otros quistes abdominales cuyas imágenes no habían sido reveladas en los estudios a los que se las había sometido.

  9. Cerebellopontine angle epidermoid showing a positive enhancement upon metrizamide CT cisternography

    Hasegawa, Takeshi; Wakamatsu, Koichi; Fujii, Toshiharu; Ito, Haruhide; Yamamoto, Shinjiro; Nagata, Izumi

    1985-04-01

    A case of epidermoid tumor in the left cerebellopontine angle cistern is reported in a 43-year-old woman with left trigeminal neuralgia. Plain CT scan revealed a low density area at the left cerebellopontine angle and left ambient cisterns, which could not be differentiated from their enlargement. Metrizamide CT cisternography showed an irregular, high density pattern in the low density filling defect which was extending into the suprasellar and interpeduncular cisterns. The developmental mechanism of this specific finding in the metrizamide CT cisternography was discussed on the basis of morphological characteristics of epidermoid tumor.

  10. Leech therapy for epidermoid cysts and review of the literature

    Abbas Rasi

    2014-01-01

    Full Text Available Hirudo medicinalis sucks blood directly through the external mammalian skin. We recently observed a healthy 64-year-old Iranian man, who presented with numerous asymptomatic multilobular oval-to-round well-defined 0.5 to 1.5 cm cystic lesions with central umbilication (central black eschar over the upper portion of his chest. We made the diagnosis of epidermoid cyst, giant comedone and leech bite on the basis of the constellation of clinical features. The patient was treated with oral ciprofloxacin at a dose of 2 g daily, and 2% topical erythromycin solution. Despite improvement, the evidence of cystic lesions persisted. There was no history of similar lesions in any other family member. There was no history of trauma. The patient was not using any topical or systemic medication. Two weeks before his visit, he had a history of leech therapy under the supervision of a general practitioner. His medical history was significant for leech therapy of the lesions, five days previously. He was followed up for another two weeks and after disappearance of the inflammation, with the patient under local anesthesia, the well-circumscribed mass was completely evacuated with a sharp curette and comedone extractor. The patient was subsequently lost to follow-up. Conclusion: Considering the efficacy of leeches, it would be favorable to breed a germ-free leech. In Iran, the use of the leeches in surgery, in recent years, has been infrequent. It appears that the positive effects of this ancient remedy may now be explained through scientific methods, promising potentially even more uses of this admirable creature in medicine.

  11. Polygenic susceptibility to testicular cancer

    Litchfield, Kevin; Mitchell, Jonathan S; Shipley, Janet;

    2015-01-01

    BACKGROUND: The increasing incidence of testicular germ cell tumour (TGCT) combined with its strong heritable basis suggests that stratified screening for the early detection of TGCT may be clinically useful. We modelled the efficiency of such a personalised screening approach, based on genetic r...

  12. Drugs Approved for Testicular Cancer

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for testicular cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.

  13. Bilateral hypertrophic olivary degeneration following surgical resection of a posterior fossa epidermoid cyst

    Vaidhyanath, R; Thomas, A; MESSIOS, N

    2010-01-01

    Hypertrophic olivary degeneration is a result of a primary lesion damaging the dento-rubro-olivary pathway. It is a transynaptic form of degeneration and is unique, causing hypertrophy rather than atrophy of the inferior olivary nucleus. We report a case of bilateral hypertrophic olivary degeneration following surgical excision of a posterior fossa epidermoid cyst and review the relevant literature.

  14. Radiotherapy for Epidermoid Carcinoma of the Anus: Thirty Years' Experience

    Purpose: To evaluate the factors associated with disease control and morbidity after radiotherapy for anal carcinoma. Methods and Materials: Between 1975 and 2005, 194 patients with localized epidermoid anal carcinoma underwent radiotherapy. Treatment evolved from radiotherapy with or without surgery, to preoperative chemoradiotherapy, to definitive chemoradiotherapy (CRT). The radiotherapy techniques also evolved. Results: With a median follow-up of 61 months, 57 patients had persistence or recurrence, 9 of whom were successfully salvaged, resulting in 146 (75%) ultimately free of disease (UNED). Univariate analysis for UNED survival showed a strong association with the T and N stage (5-year UNED rate, 88.5% ± 3.4% for those with Stage T1-T2N0; 70.1% ± 4.2% for Stage T3N0; and 52.7% ± 6.6% for Stage III; p > .001) and mobility on palpation (5-year UNED rate, 89.2% ± 4.6% for those with mobile tumors vs. 59.3% ± 6.1% for those with tethered/fixed tumor; p > .001). No association was found with gender, age, preoperative vs. definitive CRT, or human immunodeficiency virus status. The 20 human immunodeficiency virus+ patients all received CRT. The radiotherapy factors associated with Grade 3 or greater late morbidity included anorectal morbidity with tumor dose (29% with a dose ≥55 Gy vs. 9% otherwise), small bowel injury with technique (9% with anteroposterior-posteroanterior supine vs. 0.7% with multiple fields prone), and bone injury with femoral head dose (9% with a dose of ≥44 Gy vs. 0.7% otherwise). Of the 194 patients, 56 had 68 additional malignancies, mainly either antedating the anal cancer or outside the radiation fields. Conclusion: Our results have confirmed that CRT is an effective approach. Patients with human immunodeficiency virus can be treated with CRT. Tumor mobility significantly predicts the outcome; the implications for management are discussed. We also discuss the treatment planning implications of the late morbidity findings. The

  15. Impalpable Testicular Seminoma Identified on Sonoelastography

    Eric M. Ghiraldi

    2015-09-01

    Full Text Available The role of sonoelastography in diagnosing cancerous masses has increased since the advent of elastography as an ultrasound modality. Its ability to display differences in the mechanical properties of cancerous masses compared to normal surrounding tissue has shown benefit in increasing the accuracy of diagnosing malignant breast and thyroid masses and has shown early potential in accomplishing better targeted prostate biopsies. To date, the literature is limited in the number of studies describing the use of sonoelastography for testicular masses. We describe a 34-year-old man who presented with an incidental finding of an impalpable hypoechoic testicular mass on grayscale ultrasound during an infertility work-up. Sonoelastography was performed displaying intermediate testicular elastic properties. Upon frozen section of the mass during surgical exploration, classic testicular seminoma was diagnosed and subsequent radical orchiectomy was performed. We would like to use this atypical presentation of testicular seminoma to review the potential role of elastography for diagnosing testicular cancer.

  16. Testicular Pain Associated With Minocycline Use

    Victor Kucherov; William Hulbert; Guan Wu

    2015-01-01

    Two males ages 16 and 23 years presented with new testicular pain while taking minocycline. Both patients experienced resolution of their symptoms only after minocycline discontinuation. Testicular pain with minocycline use has been previously described, however only in the setting of systemic autoimmune reactions (which were absent here). These cases represent probable rare adverse reactions to minocycline. For patients taking minocycline who experience otherwise unexplained testicular pain,...

  17. Testicular Pain Associated With Minocycline Use

    Victor Kucherov

    2015-05-01

    Full Text Available Two males ages 16 and 23 years presented with new testicular pain while taking minocycline. Both patients experienced resolution of their symptoms only after minocycline discontinuation. Testicular pain with minocycline use has been previously described, however only in the setting of systemic autoimmune reactions (which were absent here. These cases represent probable rare adverse reactions to minocycline. For patients taking minocycline who experience otherwise unexplained testicular pain, a trial discontinuation of this medication should be considered.

  18. Microdissection testicular sperm extraction: an update

    Dabaja, Ali A; Schlegel, Peter N.

    2012-01-01

    Patients with non-obstructive azoospermia (NOA) were once considered to be infertile with few treatment options due to the absence of sperm in the ejaculate. In the last two decades, the advent of intracytoplasmic sperm injection (ICSI), and the application of various testicular sperm retrieval techniques, including fine needle aspiration (FNA), conventional testicular sperm extraction (TESE) and microdissection testicular sperm extraction (micro-TESE) have revolutionized treatment in this gr...

  19. Testicular biopsy: clinical practice and interpretation

    Dohle, Gert R; Elzanaty, Saad; van Casteren, Niels J

    2011-01-01

    Testicular biopsy was considered the cornerstone of male infertility diagnosis for many years in men with unexplained infertility and azoospermia. Recent guidelines for male infertility have limited the indications for a diagnostic testicular biopsy to the confirmation of obstructive azoospermia in men with normal size testes and normal reproductive hormones. Nowadays, testicular biopsies are mainly performed for sperm harvesting in men with non-obstructive azoospermia, to be used for intracy...

  20. TESTICULAR CAPILLARY HEMANGIOMA: DESCRIPTION OF A CASE

    A. S. Markova

    2014-07-01

    Full Text Available The paper describes a clinical case of testicular capillary hemangioma in a 24-year-old man undergone a partial resection of the testis with the intraoperative morphological examination. Testicular capillary hemangioma is a rare benign tumor of a vascular origin, which can be similar to malignant testicular tumors on the clinical presentation, as well as on the imaging methods, in particular to seminoma. The intraoperative histological study can assist in avoiding organ-removing surgical interventions in diagnostically ambiguous cases if a benign testicular tumor is diagnosed.

  1. Giant Ovarian Cyst: a Case Report Quiste gigante de ovario: presentación de un caso

    Mario Joel Arroyo Díaz

    2011-11-01

    Full Text Available The giant cysts ovarian growths are rare in the gynecological conditions. We present the case of a patient of 62 years of age, of white color of the skin, weight 73 kg. He came to the General Teaching Hospital "Enrique Cabrera" referring volume increase progressive on the abdomen for a year and a half of evolution without another symptom companion in its beginning, but in recent months caused her lack of air before the efforts, urinated with more frequent than usual and with a lack of appetite. He was diagnosed with cystic mass dependent on ovary, by ultrasonography and computed axial tomography. The practical laparotomy and was resected ovarian cyst left from 21 kg in weight. The anatomopathological study further reported a mucinous cystadenoma ovarian tumor Brenner associated.Los quistes gigantes de ovario son tumoraciones poco frecuentes en las afecciones ginecológicas. Se presenta el caso de una paciente de 62 años de edad, de color de piel blanca, peso 73 kg. que acudió al Hospital General Docente “Enrique Cabrera” refiriendo aumento progresivo de volumen del abdomen, de un año y medio de evolución sin otro síntoma acompañante en su comienzo, pero en los últimos meses le provocaba falta de aire ante los esfuerzos, orinaba con más frecuencia de lo acostumbrado y con falta de apetito. Se le diagnosticó una masa quística dependiente de ovario, por ultrasonografía y Tomografía Axial Computarizada. Se practicó laparotomía y se resecó quiste de ovario izquierdo de 21 kg. de peso. El estudio anatomopatológico ulterior reportó un cistoadenoma mucinoso de ovario con tumor de Brenner asociado.

  2. Radiografía periapical como herramienta en el diagnóstico y tratamiento de quiste periapical

    J. Verbel Bohórquez

    2015-02-01

    Full Text Available Introducción: El quiste periapical es una lesión inflamatoria común de los maxilares, que al alcanzar un tamaño significativo, causa deformidad del hueso afectado, retención o incluso el desplazamiento de dientes adyacentes. Se presentó caso de paciente que acudió a consulta odontológica, por presencia de sintomatología dolorosa durante el consumo de alimentos. Al examen clínico se observó encía adherida con presencia de inflamación y enrojecimiento a nivel de órgano dentario 14; radiográficamente se evidenció imagen radiolúcida unilocular, bien definida, abarcando dicho órgano dentario. La lesión fue eliminada quirúrgicamente con la posterior aplicación de material sellador. En el control postoperatorio se observó adecuado proceso de cicatrización y ausencia de sintomatología. Discusión: Se reporta caso de quiste periapical, que ocupaba el periápice de órgano dentario posterosuperior derecho. Radiográficamente se evidenció variabilidad mínima en el tamaño de la imagen. Se describe su resección quirúrgica y se informan los hallazgos de histopatología. En la revisión bibliográfica realizada se determinó la importancia de la elección de las radiografías periapicales en el área de endodoncia, y su papel en el diagnóstico, planificación de tratamiento y seguimiento de las piezas dentarias y tejidos circundantes comprometidos, pese a los inconvenientes de la técnica radiográfica.

  3. Fibroma ameloblástico versus quiste folicular hiperplásico Ameloblastic fibroma versus hyperplastic follicular cyst

    J. Azúa-Romeo

    2004-06-01

    Full Text Available Resumen: El fibroma ameloblástico (FA es un tumor odontogénico mixto, compuesto por tejido mesenquimal y epitelio odontogénico, representando el 2% de los tumores odontogénicos, mientras que el quiste dentígero o folicular (QF, el segundo quiste odontogénico en frecuencia, está compuesto exclusivamente por tejido conjuntivo laxo (mesénquima, si bien, el saco fibroso puede contener restos de epitelio odontogénico incluidos, dando lugar a una imagen histológica muy similar. La importancia de esta diferenciación radica en el tratamiento, que es ligeramente más agresivo en el FA y en el comportamiento biológico, ya que el FA puede derivar en un sarcoma ameloblástico, y el QF puede evolucionar hacia ameloblastoma y más raramente carcinoma mucoepidermoide.Abstract: Ameloblastic fibroma (AF is a mixed odontogenic tumor composed of mesenchymal tissue and odontogenic epithelium, accounting for 2% of all odontogenic tumors, while dentigerous or follicular cyst (FQ, second odontogenic cyst in frequency, is formed exclusivelly by soft conective tissue (mesenchyme. Nevertheless, hiperplastic fibrous sac may contain rests of odontogenic epithelium, showing a similar histologic pattern. The importance of an adequate differentiation lies in the treatment, which is slightly aggresive for AF, and regarding the biological behaviour of both lesions, since AF might become in an ameloblastic sarcoma, while over an FQ could develope an ameloblastoma or even a mucoepidermoid carcinoma.

  4. Intra-Abdominal Testicular Seminoma in a Woman with Testicular Feminization Syndrome

    Darshana D. Rasalkar

    2011-01-01

    Full Text Available We report a case of intra-abdominal testicular tumor in a 36-year-old married lady presenting with chief complaints of primary amenorrhea. The patient was later diagnosed with testicular feminization syndrome, a form of male pseudohermaphroditism. This testicular tumor was histologically proven as seminoma. Due to rarity, imaging findings in patients with testicular feminization syndrome and intraabdominal testicular tumor have been poorly documented. So far, only one case report had described the combined role of CT and MR imaging in intraabdominal testicular sex-cord stromal tumor. To our knowledge, this case is first to document USG and MR imaging in addition to MR spectroscopy features in intraabdominal testicular seminoma.

  5. Primary testicular lymphoma: a case report

    Cengiz Demir

    2010-06-01

    Full Text Available Primary testicular lymphomas are rare malignancy. We discussed the patient who had referred with mass into left testis at 73 years old diagnosis as diffuse large B-cell testicular lymphoma. Systemic chemotherapy (R-CHOP was given to the patient. Prophylactic radiotherapy was performed for the contralateral testis and central nervous system. Complete remission was achieved in the patient.

  6. Phthalate excretion pattern and testicular function

    Joensen, Ulla Nordström; Frederiksen, Hanne; Jensen, Martin Blomberg; Lauritsen, Mette Petri; Olesen, Inge Ahlmann; Lassen, Tina Harmer; Andersson, Anna-Maria; Jørgensen, Niels

    2012-01-01

    In animals, some phthalates impair male reproductive development and function. Epidemiological studies have reported inconsistent evidence of associations between phthalates and markers of human testicular function.......In animals, some phthalates impair male reproductive development and function. Epidemiological studies have reported inconsistent evidence of associations between phthalates and markers of human testicular function....

  7. Angiography of the testicular artery. IV

    Magnification angiography of the testis with selective injection into the testicular artery has been performed in patients with different lesions in the scrotum, either real or suggested. Characteristic angiographic appearances were found in epididymitis, testicular torsion, tumor, hematoma and hydrocele. (Auth.)

  8. Quiste de Gorlin asociado a Odontoma: reporte de un caso con su tratamiento quirúrgico Gorlin cyst associated with odontoma: Case report with surgical treatment

    P. Villarroel Castro

    2005-12-01

    Full Text Available El quiste de Gorlin es un quiste odontogénico que puede presentarse en dos variedades, una quística rodeada por epitelio y de carácter benigno, y una neoplásica localmente agresiva. Se presenta elcaso de una mujer de 18 años con aumento de volumen facial indoloro en región infraorbitaria izquierda. Se realiza la exéresis total de la lesión. Con el estudio histopatológico se obtiene el diagnóstico definitivo de quiste de Gorlin asociado a odontoma. Luego de controles por 3 años, se observa el restablecimiento de la simetría facial, una adecuada regeneración ósea y de los tejidos adyacentes, sin signos de recidiva.Gorlin cyst is an odontogenic cyst that may appear as two types, one cystic and surrounded by epithelium of a benign nature, and the other a locally aggressive neoplasm. The case is presented of an 18-year-old female that had experienced an increase in facial volume in the left infraorbital area that was painless. Total exeresis of the lesion was carried out. The histopathologic study provided the definitive diagnosis of Gorlin cyst associated with odontoma. After a follow-up of three years, facial symmetry was reestablished, there was adequate regeneration of bone and of the adjacent tissue, and there were no signs of relapse.

  9. What Are the Risk Factors for Testicular Cancer?

    ... Do we know what causes testicular cancer? Can testicular cancer be prevented? Previous Topic What are the key statistics about ... 2016 Back to top » Guide Topics What Is Testicular Cancer? Causes, Risk Factors, and Prevention Early Detection, Diagnosis, and Staging Treating Testicular Cancer ...

  10. From gonocytes to testicular cancer

    Rajpert-de Meyts, Ewa; Hoei-Hansen, Christina E

    2007-01-01

    , which demonstrated a close similarity of CIS to primordial germ cells and gonocytes with many features of embryonic stem cells. The arrest of germ-cell differentiation is thus the key first event, which may be followed by malignant transformation and overt germ-cell cancer in young adult age, usually......Testicular germ-cell tumors occur primarily in young individuals, and the tumors in this age group (seminomas or nonseminomas) are derived from a preinvasive precursor cell called carcinoma in situ (CIS) or intratubular germ-cell neoplasia. These tumors have been a growing problem, especially in...

  11. Epidermoid cyst in the floor of the mouth of a 3-year-old.

    Pascual Dabán, Rossana; García Díez, Eloy; González Navarro, Beatriz; López-López, José

    2015-01-01

    Epidermoid cysts are a rare entity in the oral cavity and are even less frequent in the floor of the mouth, representing less than 0.01% of all the cases. We present the case of a 3-year-old girl with a growth in the floor of the mouth with 2 months of evolution and without changes since it was discovered by her parents. The lesion was asymptomatic; it did not cause dysphagia, dyspnea, or any other alteration. A CT scan with contrast was done which revealed the location and exact size of the lesion, allowing an intraoral approach for its excision. The histological examination confirmed the clinical speculation of an epidermoid cyst. PMID:25694831

  12. Epidermoid Cyst in the Floor of the Mouth of a 3-Year-Old

    Rossana Pascual Dabán

    2015-01-01

    Full Text Available Epidermoid cysts are a rare entity in the oral cavity and are even less frequent in the floor of the mouth, representing less than 0.01% of all the cases. We present the case of a 3-year-old girl with a growth in the floor of the mouth with 2 months of evolution and without changes since it was discovered by her parents. The lesion was asymptomatic; it did not cause dysphagia, dyspnea, or any other alteration. A CT scan with contrast was done which revealed the location and exact size of the lesion, allowing an intraoral approach for its excision. The histological examination confirmed the clinical speculation of an epidermoid cyst.

  13. Epidermoid cyst of the outer ear: A case report and review of literature

    Alka M Dive

    2012-01-01

    Full Text Available The purpose of this article is to present a rare case of epidermoid cyst of the outer ear in a 38-year-old male patient. During clinical examination, a soft, cystic, globular, and non-tender swelling with restricted motility and well-defined margins was seen in the retroauricular region. Skin over the swelling was normal and not attached to it. The chosen treatment was total surgical removal. The histopathological findings confirmed the diagnosis of epidermoid cyst, characterized by presence of cyst cavity lined by stratified squamous epithelium with orthokeratin production. The lumen was filled with keratin. The connective tissue capsule consisted of fibrocellular stroma with numerous endothelial lined blood capillaries, which were engorged with red blood cells. The proposed treatment was considered successful, as there was no recurrence.

  14. Porfiromycin in the management of epidermoid and transitional cell cancer: a phase II study.

    Panettiere, F J; Talley, R W; Torres, J; Lane, M

    1976-07-01

    Porifiromycin has been tested in many groups of patients over the past several years (1-7). This report is an analysis of greater than 100 patients with epidermoid and urinary tract transitional cell carcinomas treated with this agent. A review of these data and the available literature on this agent shows that porfiromycin offers definite usefulness in disseminated squamous cell carcinomas of the cervix, and definite but lesser effectiveness in epidermoid carcinomas of the lung, the head and neck region, and other sites. Responsiveness was also demonstrated in transitional cell carcinomas of the urinary tract. Toxicity was tolerable and consisted primarily of myelosuppression and local skin necrosis in sites where extravasation had occurred. PMID:795539

  15. Trigeminal Neuralgia Caused by Pontocerebellar Angle Epidermoid Tumor: A Case Report and Review of Literature

    Muhammet Bahadır Yılmaz; Semra Yılmaz; Ayhan Tekiner

    2015-01-01

    Trigeminal neuralgia (TN) is the most commonly seen craniofacial pain syndrome. Etiology of TN can be divided into classical (idiopathic and vascular compression) and symptomatic (tumor, demyelinating, and ischemic) types. Especially, symptomatic trigeminal neuralgia is seen with tumors located in the cerebellopontine angle. Epidermoid tumors comprise about 1% of all brain tumors and 5% of tumors located in the cerebellopontine angle. These tumors may present with trigeminal neuralgia due to ...

  16. Splenic Epidermoid Cyst during Pregnancy; Case Report and Review of the Literature

    Majid Forouzesh

    2013-10-01

    Full Text Available Cystic disease of the spleen is not frequently encountered in surgical practice. It is broadly classified as parasitic and non-parasitic, the latter being a rare entity. In this case report, an epidermoid cyst of spleen led to acute abdomen in young age pregnant woman is presented.A 26-year-old woman with 15 weeks gestational age second pregnancy referred to emergency ward with left upper quadrant pain and tenderness that ultra sonography revealed large cyst (100х110mm with internal echo in spleen in favor of hydatic cyst or abscess. The patient was managed medically for one week but developed her abdominal pain, epigastric fullness, anorexia and fever. New sonography was done for her and large cyst was detected in spleen (120х110mm. She had severe pain accompanied with anorexia and vomiting. Fetus was normal in sonography. Exploratory laprotomy with splenectomy was performed. Splenomegaly (200х130х90mm with a cyst without any adhesion and inflammation was detected. Histopathology examination showed epidermoid cyst of spleen. (140х10х90mm. Though splenic epidermoid cyst is an uncommon entity, it should be considered in the differential diagnosis of an abdominal mass in a young individual. An attempt should be made to preserve the spleen provided there is adequate parenchyma otherwise splenectomy is the rule.

  17. Radiosurgery of epidermoid tumors with gamma knife. Possiblity of radiosurgical nerve decompression

    Long-term results of radiosurgery for epidermoid tumors are reported. There are 7 cases including 2 males and 5 females, ages ranging from 6 to 46 (mean: 33.3 years). At radiosurgery whole tumor was covered in 4 cases and partially covered in 3 cases in attempting to relieve cranial nerve signs like trigeminal neuralgia and facial spasm. The mean maximum and marginal doses were 25.6 Gy and 14.6 Gy respectively. In the mean follow-up of 52.7 months, all the tumors showed good tumor control without any progression and tumor shrinkage has been confirmed in 2 out of the 7 cases. Symptomatic trigeminal neuralgia improved or disappeared in all 4 cases and facial spasm disappeared in one. No neurological deterioration was found in any of the cases after the treatment. In conclusion, it is apparent that epidermoid tumors do respond well to radiosurgery and the accompanying hyperactive dysfunction of cranial nerves is significantly improved by gamma knife treatment with either entire or partial tumor coverage. Therefore the radiosurgical nerve decompression for epidermoid tumor seems to be achieved by gamma-radiosurgery. (author)

  18. Atypical appearance of epidermoid cyst in tongue’s ventral surface

    Claudio Maranhão Pereira

    2011-04-01

    Full Text Available Introduction: Epidermoids cysts are benign and rare lesions in oral cavity. It presents as a nodular lesion of sessile base, soft to palpation. In the oral cavity, it most happens on the floor of the mouth’s midline. Without treatment, these lesions can lead to dysphagia, dysphonia and dyspnea due to reach a large size. Objective: To report a case of a 12-year-old boy presenting a lesion on the tongue’s ventral surface causing difficult to swallow. Case report: The patient was referred to the School of Dentistry of Paulista University, complaining about an asymptomatic nodule on the tongue’s ventral surface, lasting for 10 months. Clinical examination showed the extensive fibrous mass on the tongue’s medium anterior ventral surface. Conclusion: With a clinical diagnosis of dermoid, epidermoid cyst, or lipoma, an excisional biopsy was performed. Histological examination was consistent to the diagnosis of epidermoid cyst. The patient was followed up and 2 years after surgery there was no sign of recurrence.

  19. Prognostic significance of s-phase fraction detected by antithymidine antibodies in epidermoid cervix carcinomas

    Purpose: To assess the predictive value of pretreatment proliferative activity of epidermoid cervix carcinoma cells with respect to short- and long-term results of radiotherapy. Methods and Materials: The proliferative activity of 25 epidermoid cervix carcinomas was evaluated as the immunofluorescent labelling index (LI) by rabbit antithymidine antibodies reacting specifically with single-stranded DNA of replication forks in S-phase cells. The short-term clinical outcome was estimated at 3-6 months after treatment by visual and palpatory examination. Three-year follow-up data were obtained through hospital charts and correspondence with referring physicians for only 19 patients. Results: There was no statistically significant association between LI and such conventional prognostic factors as clinical stage. The LI value of cervix carcinomas was significantly associated with complete regression at 3-6 months after radiotherapy and 3-year disease-free survival. Complete regression at 3-6 months was observed in 87.5% patients with fast proliferating tumors (LI > 7.0%), and only in 41.2% patients with slowly proliferating tumors (p = 0.03). Probability of 3-year disease-free survival was 85.7% in patients with fast proliferating tumors and 50.0% in those with slowly proliferating tumors (p = 0.05). Conclusions: The immunofluorescent LI of epidermoid cervix carcinoma is able to provide prognostic information on short-term tumor response to radiotherapy and disease-free survival

  20. Isolated thoracic (D5 intramedullary epidermoid cyst without spinal dysraphism: A rare case report

    Sudhansu Sekhar Mishra

    2015-01-01

    Full Text Available Spinal epidermoid cyst, congenital or acquired, is mainly congenital associated with spinal dysraphism, rarely in isolation. Intramedullary epidermoid cysts (IECs are rare with less than 60 cases reported so far; isolated variety (i.e., without spinal dysraphism is still rarer. Complete microsurgical excision is the dictum of surgical treatment. A 14-year-old boy presented with 4-month history of upper backache accompanied with progressive descending paresthesia with paraparesis with early bladder and bowel involvement. His condition deteriorated rapidly making him bedridden. Neurological examination revealed upper thoracic myeloradiculopathy probably of neoplastic origin with sensory localization to D5 spinal level. Digital X-ray revealed no feature suggestive of spinal dysraphism. Contrast magnetic resonance imaging (MRI characteristics clinched the presumptive diagnosis. Near-total microsurgical excision was done leaving behind a small part of the calcified capsule densely adhered to cord. Histopathological features were confirmative of an epidermoid cyst. Postoperatively, he improved significantly with a gain of motor power sufficient to walk without support within a span of 6 months. Spinal IECs, without any specific clinical presentation, are often diagnosed based upon intraoperative and histopathological findings, however early diagnosis is possible on complete MRI valuation. Complete microsurgical excision, resulting in cessation of clinical progression and remission of symptoms, has to be limited to sub-total or near-total excision if cyst is adherent to cord or its confines.

  1. Resection of large recurrent third ventricular epidermoid tumors through the posterior interhemispheric transcallosal approach.

    Hendricks, Benjamin K; Cohen-Gadol, Aaron A

    2016-01-01

    Epidermoid cysts or tumors comprise 1% of intracranial tumors with a predilection for the cerebellopontine angle or parasellar cisterns. These tumors are derived from an ectopic ectodermal implant seeded between fusing ectodermal surfaces. This results in a benign proliferation of stratified squamous epithelium along a cyst wall with a lumen composed of hyperkeratotic material derived from the desquamating cells. Surgical intervention is the treatment of choice for symptomatic patients. There is no role for radiotherapy or chemotherapy in the treatment of these lesions, including for residual or recurrent disease. The inherent adhesion of the proliferating epithelial lining to surrounding neurovascular structures significantly complicates attempts at gross-total resection. Epidermoid tumors or cysts are rarely reported within the third ventricular region. In this video, the authors demonstrate the technique of right-sided posterior interhemispheric transcallosal approach for maximal resection of a complex recurrent third ventricular epidermoid tumor with lateral ventricular extension. The video can be found here: https://youtu.be/wbXp7mc0vT4 . PMID:26722690

  2. [Fertility in testicular cancer patients].

    Shin, Takeshi; Miyata, Akane; Arai, Gaku; Okada, Hiroshi

    2015-03-01

    Testicular cancer(TC)is the most common and curable cancer affecting men of reproductive age. Successful treatment approaches have resulted in longer life expectancy in TC survivors. The most frequently used treatment for TC is a combination of inguinal orchiectomy, and either radiotherapy or cisplatin-based chemotherapy. In many TC patients, sperm quality is already abnormal and there may even be a lack of viable spermatozoa at the time of diagnosis. Therefore, the effect of cancer treatment on fertility is a potentially significant issue. Fertility preservation in these men has become essential and needs to be discussed prior to the start of cancer treatment. The only currently established fertility preservation method is the cryopreservation of sperm before therapy. For most patients seeking cryopreservation, the semen sample is collected via masturbation. If the patient is unable to ejaculate for any reason, other techniques such as vibratory stimulation and electroejaculation can be performed. In azoospermic or severely oligozoospermic patients, testicular sperm extraction at the time of the inguinal orchiectomy is a useful technique for obtaining spermatozoa before cytotoxic therapy. We herein present an overview of the current topics on fertility in TC patients, including the effects of surgery, chemotherapy, and radiation therapy. We also describe the strategy for fertility preservation in these patients. PMID:25812494

  3. [Verification of testicular cancer guidelines].

    Nonomura, Norio; Azuma, Haruhito

    2012-12-01

    Testicular cancer is a rare disease that affects 1-2 in 100,000 people in Japan ; however, it is a very significant disease in that it has a high prevalence amongst young adults aged in their 20s and 30s and it brings about metastasis from a relatively early stage. The 2009 edition of the Testicular Cancer Clinical Practice Guidelines sets out a detailed summary of 32 clinical questions (CQ) considered necessary in routine clinical practice across the fields of epidemiology, diagnosis, treatment, etc, in the form of recommendations and commentary. These CQs are considered extremely important in understanding the foundation of future testicular cancer treatment guidelines. In this symposium, five doctors gave lectures consisting of the following contents in which they validated the guidelines and gave concrete clinical practice examples through cases they had experienced themselves with regards to the treatment strategies for (1) stage I patients, (2) patients with advanced cancer and (3) patients with extragonadal germ cell tumors. (1) Stage I patients : In seminoma cases, the doctors focused on the relapse prevention effect provided by single-agent carboplatin adjuvant chemotherapy. In non-seminoma cases, treatment options were considered according to risk based on the presence or absence of vascular invasion, a prognostic factor. (2) Patients with advanced cancer : 30% of testicular cancers are metastatic and progress to advanced cancer. In refractory cases resistant to bleomycin, etoposide and cisplatin therapy, etoposide ifosfamide, and cisplatin therapy and vinblastine, ifosfamide and cisplatin therapy have been used, but without satisfactory results and the development of new salvage chemotherapy is an important issue. The therapeutic strategies against advanced testicular cancer were narrowed down to (2) -1) therapeutic effects from ultra-high-dose chemotherapy, (2) -2) salvage chemotherapy in cases where residual tumors are observed in induction

  4. Testicular cancer: addressing the psychosexual issues.

    Moore, Annamarie

    2012-01-31

    Testicular cancer is the most common malignancy in men aged 15-35 years and predominantly occurs at a time in a man\\'s life when important decisions about marriage, starting a family and a professional career are being made. While treatments for testicular cancer are very successful, they can have a major impact on the person\\'s sexuality and sense of self. The focus of this article is on exploring the impact of cancer treatments for testicular cancer on men\\'s sexuality and how nurses can respond to their concerns in a sensitive and informed manner.

  5. Educating young men about testicular cancer: support for a comprehensive testicular cancer campaign.

    Wanzer, Melissa Bekelja; Foster, S Catherine; Servoss, Timothy; LaBelle, Sara

    2014-01-01

    Despite the prevalence of testicular cancer among men 15-39 years of age, little has been done to increase awareness of this disease or educate males about its prevention. To fill this gap, the Standard Model of Health Communication was incorporated to design and implement a comprehensive testicular cancer campaign among male college students. To test the effectiveness of these messages, college students (N = 220) completed measures before and after the campaign. In addition, the authors obtained a control group of male college students (N = 52) who were not exposed to the messages. Survey items assessed awareness of testicular cancer and behaviors related to testicular cancer. Participants' knowledge of testicular cancer and likelihood of conducting a testicular self-exam increased significantly after being exposed to the campaign information. Men who were exposed to testicular cancer messages were more knowledgeable about testicular cancer and were more likely to conduct testicular self-examinations than were men in the control group. PMID:24117344

  6. Treatment Options by Stage (Testicular Cancer)

    ... and nonseminomas . These 2 types grow and spread differently and are treated differently. Nonseminomas tend to grow and spread more quickly ... trials is available from the NCI website . To Learn More About Testicular Cancer For more information from ...

  7. Occupational Causes of Testicular Cancer in Adults

    L Fritschi

    2010-09-01

    Full Text Available Testicular cancer is one of the commonest cancers in men of working age, and is increasing in incidence in Europe and North America. One suggested mechanism of causation is that there is impaired differentiation of germ cells in the pre- or perinatal period, followed by malignant transformation in later life, possibly by a hormonal mechanism. Endocrine disrupting chemicals (EDCs have been a major focus of interest for etiological research into testicular cancer because they interact with various hormonal pathways. Several EDCs including bisphenol A, phthalates, metals, polychlorinated biphenyls, and organochlorines have been investigated, but there are few studies and those that exist have not been able to assess exposure well. In addition, several studies, particularly those with better exposure assessment, have suggested that workers in electrical occupations have increased risks of testicular cancer. Electromagnetic radiation may have subthermal effects or may disrupt hormone release. Chronodisruption such as due to shift-work could potentially increase the risk of testicular cancer via disruption of hormonal cycles, but only one study has so far investigated this possibility. Lastly, solvent exposure, particularly to dimethylformamide, has been suggested to be associated with testicular cancer, but almost all these studies are based on job title only, with no specific assessment of solvent exposure. In conclusion, there is little evidence available on which to base definitive statements about occupational causes of testicular cancer. Future studies need to improve exposure assessment and develop ways to adjust for possible prenatal factors.

  8. Cetuximab intensifies cisplatin-induced testicular toxicity.

    Levi, Mattan; Popovtzer, Aron; Tzabari, Moran; Mizrachi, Aviram; Savion, Naphtali; Stemmer, Salomon M; Shalgi, Ruth; Ben-Aharon, Irit

    2016-07-01

    Epidermal growth factor receptor (EGFR) has proliferative properties in the testis. Cetuximab, an anti-EGFR, is administered together with chemotherapy to patients with various types of cancer. This studies aim was to investigate the effect of cetuximab on testicular function. Adult male mice were injected with cetuximab (10 mg/kg), cisplatin (8 mg/kg) or a combination of both, and killed one week or one month later. The doses were chosen by human equivalent dose calculation. Testicular function was evaluated by epididymal-spermatozoa total motile count and sperm motility, weights of testes and epididymides, and the level of anti-Müllerian hormone (AMH) in the serum. Immunohistochemistry was performed to examine germ cell proliferation (Ki-67), apoptosis (Terminal transferase-mediated deoxyuridine 5-triphosphate nick-end labelling), reserve (DAZL-Deleted in azoospermia-like, Promyelocytic leukaemia zinc-finger), blood vessels (CD34) and Sertoli cells (GATA-4). Administration of cetuximab alone increased testicular apoptosis and decreased epididymal-spermatozoa total motile count over time. When added to cisplatin, cetuximab exacerbated most of the recorded testicular parameters, compared with the effect of cisplatin alone, including testis and epididymis weights, epididymal-spermatozoa total motile count, AMH concentration, meiosis and apoptosis. In conclusion, cetuximab has only a mild effect on testicular reserve, but when added to cisplatin, it exacerbates cisplatin-induced testicular toxicity. PMID:27184186

  9. [Epidemiology and risk factors of testicular tumours].

    Kozłowski, Piotr; Starosławska, Elżbieta; Szumiło, Justyna; Jankiewicz, Małgorzata; Kozłowska, Magdalena; Burdan, Franciszek

    2016-04-01

    Testicular tumours are rare neoplasms, which most commonly affects men aged 25 to 35 years. Among young adult males it is the most common cause of testicular swelling. In recent decades, the number of cases of testicular tumours has greatly increased. The most significant predisposing factors are cryptorchidism and some endocrine disorders, especially increased levels of gonadotropins and female sex hormones. Testicular trauma, inguinal hernia, extreme values of body mass index (BMI), high-calorie diet rich in dairy products as well as high social status are also regarded as risk factors. Furthermore, some chromosomal abnormalities like increased number of chromosomes 7, 8. 12, 21 and X, loss of chromosomes 4, 5, 11, 13, 18, or Y, mutation in the gene Xq27; as well as multiplied copy of the gene i(12p) are associated with tumor development. It has been proven that high testosterone levels and regular physical activity may prevent testicular tumours. Since one of the first sign the lesion is often a lump or swelling of the testis and the appearance of abnormal structure in the scrotum routine testicular self-examination seems to be important in early detection. In all suspected cases an immediate ultrasound examination of both testicles is highly recommended. It is also advised to conduct a computerized tomography (CT) and a positron emission tomography (PET) scan for staging of the tumor to select the best mode of treatment. PMID:27137819

  10. Dexrazoxane exacerbates doxorubicin-induced testicular toxicity.

    Levi, Mattan; Tzabari, Moran; Savion, Naphtali; Stemmer, Salomon M; Shalgi, Ruth; Ben-Aharon, Irit

    2015-10-01

    Infertility induced by anti-cancer treatments pose a major concern for cancer survivors. Doxorubicin (DXR) has been previously shown to exert toxic effects on the testicular germinal epithelium. Based upon the cardioprotective traits of dexrazoxane (DEX), we studied its potential effect in reducing DXR-induced testicular toxicity. Male mice were injected with 5  mg/kg DXR, 100  mg/kg DEX, combination of both or saline (control) and sacrificed either 1, 3 or 6 months later. Testes were excised and further processed. Glutathione and apoptosis assays were performed to determine oxidative stress. Immunohistochemistry and confocal microscopy were used to study the effects of the drugs on testicular histology and on spermatogonial reserve. DXR and the combined treatment induced a striking decline in testicular weight. DEX prevented DXR-induced oxidative stress, but enhanced DXR-induced apoptosis within the testes. Furthermore, the combined treatment depleted the spermatogonial reserve after 1 month, with impaired recovery at 3 and 6 months post-treatment. This resulted in compromised sperm parameters, testicular and epididymal weights as well as significantly reduced sperm motility, all of which were more severe than those observed in DXR-treated mice. The activity of DEX in the testis may differ from its activity in cardiomyocytes. Adding DEX to DXR exacerbates DXR-induced testicular toxicity. PMID:26329125

  11. Diagnóstico y tratamiento de los quistes de colédoco: Presentación de 10 nuevos casos Diagnosis and management of choledochal cysts: A review of 10 new cases

    R. Uribarrena Amezaga; N. Raventós; Fuentes, J.; J. Elías; V. Tejedo; R. Uribarrena Echebarría

    2008-01-01

    Objetivo: analizar las técnicas diagnósticas y las distintas posibilidades terapéuticas de esta rara patología. Pacientes y métodos: presentamos un estudio retrospectivo de todos los casos de quistes de colédoco diagnosticados en nuestro hospital desde 1991. Incluye 10 nuevos casos y distintos tipos de quistes de colédoco (QC). Resultados: de los 10 pacientes diagnosticados de QC siete tenían menos de 10 años. En cuanto a los diferentes tipos de QC: 7 eran de tipo I, 1 de tipo III, 1 de tipo ...

  12. Intracranial squamous cell carcinoma developing in remnant of an epidermoid cyst:case report and literature review

    关丽明; 戚喜勋; 张景荣; 徐克; 崔丽娟; 张强

    2004-01-01

    @@ Epidermoid tumors, sometimes called "pearly tumor", because of the appearance of their outer surface, represent about 0.2%-1.8% of all the primary intracranial tumors1 and are benign developmental lesions. However in 1912, Ernst et al2 found a case of primary intracranial squamous cell carcinoma arising in an epidermoid cyst in autopsy and reported it. Hereafter, case reports about primary intracranial squamous cell carcinoma appeared in succession, especially after computed tomography (CT) and magnetic resonance imaging (MRI) were widely applied in clinical medicine. To our knowledge, few cases have been reported in our country until now. We present a case of intracranial squamous cell carcinoma developing in remnant of an epidermoid cyst 11 years after the operation resection with a review of the literature.

  13. Testicular cancer trends as 'whistle blowers' of testicular developmental problems in populations

    Skakkebaek, N E; Rajpert-De Meyts, E; Jørgensen, N; Main, K M; Leffers, H; Andersson, A-M; Juul, A; Jensen, T K; Toppari, J

    2007-01-01

    Recently a worldwide rise in the incidence of testicular germ cell cancer (TGCC) has been repeatedly reported. The changing disease pattern may signal that other testicular problems may also be increasing. We have reviewed recent research progress, in particular evidence gathered in the Nordic...... countries, which shows strong associations between testicular cancer, undescended testis, hypospadias, poor testicular development and function, and male infertility. These studies have led us to suggest the existence of a testicular dysgenesis syndrome (TDS), of which TGCC, undescended testis, hypospadias...... trends in TGCC rates of a population may be 'whistle blowers' of other reproductive health problems. As cancer registries are often of excellent quality - in contrast to registries for congenital abnormalities - health authorities should consider an increase in TGCC as a warning that other reproductive...

  14. Distensión abdominal y edemas por quiste del cordón espermático Abdomina distention and edema due to spermatic cord cyst

    Guillermo A. Keller

    2006-04-01

    Full Text Available La distensión abdominal es un síntoma común, siendo en general la presentación inicial de enfermedades sistémicas o desórdenes gastrointestinales. Otras causas son infrecuentes. Los quistes del cordón espermático son poco frecuentes, pero aún más su ubicación intraabdominal, su tamaño habitual es insuficiente para producir distensión. El paciente presentado en este caso es un varón con criptorquidia bilateral admitido por distensión abdominal, interpretada inicialmente como síndrome ascítico edematoso. La ecografía interpretó la distensión como ascitis tabicada, y la tomografía computada como debida a un gran quiste. En la exploración quirúrgica se diagnosticó un quiste gigante del cordón espermático de ubicación abdominal.Abdominal distention is a frequent symptom, being often the initial presentation of systemic diseases or gastrointestinal disorders. Other causes are uncommon. Spermatic cord cysts are infrequent, abdominal location is even rarer, and the size of the cysts is usually not enough to produce abdominal distention. In our case a man with bilateral cryptorchidism was admitted with abdominal distention and edema of the lower extremities initially interpreted as ascitic-edematous syndrome. Ultrasonography interpreted abdominal distention as septate ascites, computed tomography as a giant cyst. Exploratory surgery showed a giant spermatic cord cyst in the left spermatic cord.

  15. Public awareness of testicular cancer and testicular self-examination in academic environments: a lost opportunity

    Henry A. A. Ugboma

    2011-01-01

    Full Text Available BACKGROUND: Although testicular cancer is the most common cancer among 18- to 50-year-old males, healthcare providers seldom teach testicular self-examination techniques to clients, thus potentially missing opportunities for early detection. This form of cancer is easily diagnosable by testicular self-examination and is 96% curable if detected early. Periodic self-examination must be performed for early detection. Knowledge deficits and sociocultural norms contribute to low levels of health-related knowledge in most patients, resulting in undue delays before seeking medical advice. OBJECTIVE: Our aim is to assess the level of awareness of testicular cancer and the prevalence of the practice of testicular self-examination in academic environments to enable appropriate interventions. METHOD: A cross-sectional survey was administered to 750 consecutive males aged 18-50 years in three tertiary institutions in Port Harcourt from October 2008 to April 2009. RESULT: Knowledge or awareness of testicular cancer was poor. Almost all of the respondents were unaware that testicular lumps may be signs of cancer. A lump was typically construed as a benign carbuncle or something that could resolve spontaneously. The main factor contributing to respondents' lack of knowledge of testicular cancer was that few reported that they were "ever taught about testicular self-examination." CONCLUSION: Young adult men are unaware of their risk for testicular cancer, which is the most common neoplasm in this age group. Healthcare providers are not informing them of this risk, nor are they teaching them the simple early detection technique of self-examination of the testes.

  16. Impacto de la dieta sobre la inducción de infección con quistes de Giardia lamblia en ratas Sprague-Dawley

    Díaz-Cinco Martha Elvia; Ballesteros-Vázquez Martha Nydia; Pérez-Morales Rosalba; Mata-Haro Verónica

    2002-01-01

    Objetivo. Evaluar el efecto de la desnutrición en la inducción de la giardiosis con diferentes concentraciones de quistes de Giardia lamblia utilizando como modelo animal ratas Sprague-Dawley. Material y métodos. Es un estudio experimental efectuado entre 1995 y 1999, en el Centro de Investigación en Alimentación y Desarrollo, de la ciudad de Hermosillo, estado de Sonora, México, y cuya muestra estuvo integrada por dos grupos de 6 a 8 unidades experimentales, las cuales recibieron dos tipos d...

  17. Quiste hidatídico cerebral en niños en el Hospital Nacional Cayetano heredia: a propósito de un caso

    Daniel Guillén

    1994-06-01

    Full Text Available Se presenta el caso de una niña de 12 años de edad con siete meses de evolución de signos focales e hipertensión endocraneana progressiva. Con ayuda de la TAC se diagnosticó tumoración quística gigante compatible a hidatidosis cerebral. Se realizó craneotomía y extirpación del quiste sin complicaciones. La hidatidosis cerebral es rara, su diagnóstico es clínico-tomográfico y el tratamiento siempre es quirúrgico.

  18. Quiste hidatídico cerebral en niños en el Hospital Nacional Cayetano heredia: a propósito de un caso

    Daniel Guillén; Patricia Campos; Ildauro Aguirre; Daniel Porturas; Noriega Pedro; Marcos Alva; Alfredo Fuentes-Dávila; Wesley Alaba

    1994-01-01

    Se presenta el caso de una niña de 12 años de edad con siete meses de evolución de signos focales e hipertensión endocraneana progressiva. Con ayuda de la TAC se diagnosticó tumoración quística gigante compatible a hidatidosis cerebral. Se realizó craneotomía y extirpación del quiste sin complicaciones. La hidatidosis cerebral es rara, su diagnóstico es clínico-tomográfico y el tratamiento siempre es quirúrgico.

  19. Control químico del Nematodo quiste Heterodera trifolii en clavel miniatura Chemical control of the cyst nematode, Heterodera trifolii in miniature carnation

    Marroquin Alicia; Arbelaez Germán

    1991-01-01

    Una de las enfermedades en el cultivo del clavel recientemente registradas en Colombia es el nemátodo quiste, Heterodera trifolii. Un aumento del marchitamiento vascular ocasionado por Fusarium oxysporumof. sp. dianthi se ha observado en algunas fincas afectadas por los dos patógenos. La investigación se realizó para evaluar el efecto de varios productos químicos en el control del nemátodo, en un invernadero comercial con clavel miniatura de la variedad Red Baron. Los fumigantes DD-metilisoti...

  20. Results of radial therapy epidermoid of lungs cancer with dynamic fractionating dozes

    Under supervision there were 53 patients epidermoid of lung cancer by which radial therapy under the radical program (Muravskaja G. V. and co author 1998)was carried out . The purpose of work was studying results of radial treatment epidermoid lungs cancer under the radical program and some factors of the prognosis. The diagnosis of epidermoid lungs cancer patients has been confirmed by morphologic. All patients were under supervision more than 1 year.27 from the above stated patients (the first group) 26 patients (the second group)-less than one year lived more than 1 year (51.0%). The two year survival rate of patients of the first group has made 15.1% .Three year survival rate - 11.3% . Results correspond to the literary data(Bauman M.2001)distinction on age was not. At the analysis of distribution of patients on a degree of prevalence of a tumour it is established , that in the first group it was observed: T2NO-4;T2N1-4;T2-3N2,T3NO-1-19,accordingly, in the second group: T2 N0-3,T2N1-2;T2-3N2,T3N1-14;T2-3 N3-7. In both groups prevailed 111 degree of disease:in the first -70,9%,in the second 80.8%. But in group of patients living less than one year, in 26,9% was observed metastatic spreading tumours in the lymphatic nodes, corresponding to category N3. In the second group also much more often are atelectasis, not allowed radiographical to limit a shadow of a tumour from a shadow atelectasis (58.0±9.7% and 30.0±8.8%,p<0.05).Frequency full resorption tumours was observed in the first group in 37.0±9.3%, in the second 3.9±3.8%, almost in 10 times it is less. The received data specify direct correlation between the loco-regional control and lymphogenous distribution epidermoid lungs cancer, presence of atelectasis.In the latter case deterioration of results is probably caused by impossibility at radiological research to define border a tumour and atelectasis that is important at planning volume of irradiation.I n this connection other method of visualization are

  1. Subtotal resection and omentoplasty of the epidermoid splenic cyst: a case report

    Spahija, Gazmend S; Hashani, Shemsedin I; Osmani, Eshref A; Hoxha, Sejdullah A; Hamza, Astrit H; Gashi-Luci, Lumturije H

    2009-01-01

    Introduction Nonparasitic splenic cysts are uncommon clinical entity and because of it, there is no information regarding their optimal surgical treatment. Case presentation A 41-years-old female with incidentally diagnosed nonparasitic splenic cyst which initially was asymptomatic. After two years of follow up, the patient underwent surgery; subtotal cystectomy and omentoplasty as an additional procedure. Postoperative course was uneventful. Conclusion Short and mid term results showed that near total cystectomy with omentoplasty was a safe successful procedure for treatment of epidermoid splenic cyst. PMID:19829799

  2. Urgent penectomy in a patient presenting with epidermoid carcinoma of the penis associated to myiasis

    Antonio J. Tavares; Rodrigo Barros; Luciano A. Favorito

    2007-01-01

    The objective of this study is to describe the case of a patient presenting advanced epidermoid carcinoma of the penis associated to myiasis. A 41-year-old patient presenting with a necrotic lesion of the distal third of the penis infested with myiasis was attended in the emergency room of our hospital and was submitted to an urgent penectomy. This is the first case of penile cancer associated to myiasis described in the literature. This case reinforces the need for educative campaigns to red...

  3. Urgent penectomy in a patient presenting with epidermoid carcinoma of the penis associated to myiasis

    Antonio J. Tavares

    2007-08-01

    Full Text Available The objective of this study is to describe the case of a patient presenting advanced epidermoid carcinoma of the penis associated to myiasis. A 41-year-old patient presenting with a necrotic lesion of the distal third of the penis infested with myiasis was attended in the emergency room of our hospital and was submitted to an urgent penectomy. This is the first case of penile cancer associated to myiasis described in the literature. This case reinforces the need for educative campaigns to reduce the incidence of this disease in developing countries.

  4. Prognostic factors in megavoltage radiation therapy of central epidermoid lung carcinoma

    Radical program radiotherapy was provided to 403 patients with inoperable central epidermoid lung carcinoma that does not extend beyond one half of the thoracic cavity. Long-term therapeutic results depend on numerous factors the interrelationships of which cannot be revealed without present-day methods of data analysis. The use of computers (a method of parameter grouping and semi-automatic classification - ''teaching without a teacher'') made it possible before treatment to approach the level of group prognosis by symptoms; taking into account the time course of symptoms in the process of radiation therapy and after its termination - to reach the level of individual prognosis for 22% of the patients

  5. Relationship between testicular volume and testicular function: comparison of the Prader orchidometric and ultrasonographic measurements in patients with infertility

    Hideo Sakamoto; Yoshio Ogawa; Hideki Yoshida

    2008-01-01

    Aim: To evaluate the relationship between testicular function and testicular volume measured by using Prader orchidometry and ultrasonography (US) to determine the critical testicular volume indicating normal testicular func-tion by each method. Methods: Total testicular volume (right plus left testicular volume) was measured in 794 testes in 397 men with infertility (mean age, 35.6 years) using a Prader orchidometer and also by ultrasonography.Ultrasonographic testicular volumes were calculated as length×width×height×0.71. To evaluate volume-function relationships, patients were divided into 10 groups representing 5-mL increments of total testicular volume by each method from below 10 mL to 50 mL or more. Results: Mean total testicular volume based on Prader orchidometry and US were 36.8 mL and 26.3 mL, respectively. Semen volume, sperm density, total sperm count, total motile sperm count, and serum FSH, LH, and testosterone all correlated significantly with total testicular volume measured by either method. Mean sperm density was in the oligozoospermic range in patients with total testicular volume below 35 mL by orchidometry or below 20 mL by ultrasonography. Mean total sperm count was subnormal in patients with total testicular volume below 30 mL by orchidometry or under 20 mL by ultrasonography. Conclusion: Testicular volume measured by either ultrasonography or Prader orchidometry correlated significantly with testicular function.However, critical total testicular volume indicating normal or nearly normal testicular function was 30 mL to 35 mL using Prader orchidometer and 20 mL using ultrasonography. Prader orchidometry morphometrically and function-ally overestimated the testicular volume in comparison to US.

  6. Testicular seminoma metastasis to duodenum. Misdiagnosed as primary duodenal tumor

    Amer Hashim Al Ani

    2016-01-01

    Conclusion: High index of suspicion for testicular seminoma must be raised when treating young males with GIT complications like hemorrhage. Testicular seminoma is the most common solid tumor at this age. Sometimes it is the cause behind this complication.

  7. Epigenetic: a molecular link between testicular cancer and environmental exposures?

    DavidHVOLLE

    2012-11-01

    Here we will review chromatin modifications which can affect testicular physiology leading to the development of testicular cancer; and highlight potential molecular pathways involved in these alterations in the context of environmental exposures.

  8. Testicular defense systems: immune privilege and innate immunity.

    Zhao, Shutao; Zhu, Weiwei; Xue, Shepu; Han, Daishu

    2014-09-01

    The mammalian testis possesses a special immunological environment because of its properties of remarkable immune privilege and effective local innate immunity. Testicular immune privilege protects immunogenic germ cells from systemic immune attack, and local innate immunity is important in preventing testicular microbial infections. The breakdown of local testicular immune homeostasis may lead to orchitis, an etiological factor of male infertility. The mechanisms underlying testicular immune privilege have been investigated for a long time. Increasing evidence shows that both a local immunosuppressive milieu and systemic immune tolerance are involved in maintaining testicular immune privilege status. The mechanisms underlying testicular innate immunity are emerging based on the investigation of the pattern recognition receptor-mediated innate immune response in testicular cells. This review summarizes our current understanding of testicular defense mechanisms and identifies topics that merit further investigation. PMID:24954222

  9. Surgical therapy for testicular cancer metastatic to the liver

    Maluccio, Mary; Einhorn, Lawrence H.; Goulet, Robert J.

    2007-01-01

    In recent years improved cure rates have been achieved for testicular cancer. A better understanding of the biology of subtypes of testicular cancer and the introduction of surgical intervention has contributed greatly to how we currently approach a young man with testicular cancer. We describe here experience at our institution of the treatment, results and prognostic factors for testicular cancer metastases to the liver. Careful diagnostic work-up and planning of the therapy are required, i...

  10. Testicular defense systems: immune privilege and innate immunity

    Zhao, Shutao; Zhu, Weiwei; Xue, Shepu; Han, Daishu

    2014-01-01

    The mammalian testis possesses a special immunological environment because of its properties of remarkable immune privilege and effective local innate immunity. Testicular immune privilege protects immunogenic germ cells from systemic immune attack, and local innate immunity is important in preventing testicular microbial infections. The breakdown of local testicular immune homeostasis may lead to orchitis, an etiological factor of male infertility. The mechanisms underlying testicular immune...

  11. Comportamiento del quiste branquial en pacientes del Hospital General Docente "Ciro Redondo García", Artemisa, 1993-2009 Behavior of branchial cyst in patients admitted in the "Ciro Redondo García", General Teaching Hospital, Artemisa municipality, 1993-2009

    Juan Carlos Quintana Díaz; Josefa Dolores Miranda Tarragó; Mayrim Quintana Giralt

    2012-01-01

    El quiste branquial de origen congénito que aparece en la región lateral del cuello es, con frecuencia, motivo de consulta. Se tuvo como objetivo determinar el comportamiento de los quistes branquiales en el Hospital "Ciro Redondo García", de Artemisa en el periodo de 1993 al 2009. Se realizó un estudio descriptivo transversal de los quistes branquiales diagnosticados en pacientes intervenidos quirúrgicamente en el Servicio de Cirugía Maxilofacial. Se estudiaron la edad, el sexo, el color de ...

  12. FGF2 mediates DNA repair in epidermoid carcinoma cells exposed to ionizing radiation

    Fibroblast growth factor 2 (FGF2) is a well-known survival factor. However, its role in DNA repair is poorly documented. The present study was designed to investigate in epidermoid carcinoma cells the potential role of FGF2 in DNA repair. The side population (SP) with cancer stem cell-like properties and the main population (MP) were isolated from human A431 squamous carcinoma cells. Radiation-induced DNA damage and repair were assessed using the alkaline comet assay. FGF2 expression was quantified by enzyme linked immunosorbent assay (ELISA). SP cells exhibited rapid repair of radiation induced DNA damage and a high constitutive level of nuclear FGF2. Blocking FGF2 signaling abrogated the rapid DNA repair. In contrast, in MP cells, a slower repair of damage was associated with low basal expression of FGF2. Moreover, the addition of exogenous FGF2 accelerated DNA repair in MP cells. When irradiated, SP cells secreted FGF2, whereas MP cells did not. FGF2 was found to mediate DNA repair in epidermoid carcinoma cells. We postulate that carcinoma stem cells would be intrinsically primed to rapidly repair DNA damage by a high constitutive level of nuclear FGF2. In contrast, the main population with a low FGF2 content exhibits a lower repair rate which can be increased by exogenous FGF2. (authors)

  13. Segmental testicular infarction in a young man simulating a testicular tumor.

    Kim, Hee Kyung; Goske, Marilyn J; Bove, Kevin E; Minovich, Eugene

    2009-04-01

    A 19-year-old boy presented with a 48-hour history of acute onset severe right scrotal pain with minimal scrotal swelling. High-frequency US including color Doppler demonstrated a wedge-shaped, heterogeneous, avascular testicular mass diagnosed preoperatively as a segmental testicular infarction (STI). This was proved at surgery and subsequent histology. The preoperative diagnosis of STI was suggested based on the young man's presentation of severe pain and the sonographic appearance of the mass. Entertaining the preoperative diagnosis of STI from a testicular tumor is important for testis-sparing surgery even though STI in the pediatric age group is extremely rare. PMID:19214495

  14. Isolated relapse ganglions of epidermoid carcinomas of superior aero-digestive ways:Does the brachytherapy have its place

    The brachytherapy of isolated ganglions relapses of epidermoid carcinomas allows the ganglions control to three years in 25% of cases. Taking into account its toxicity (6% of deceases) and the unfavorable prognosis of the illness, a cervical ganglion surgery must be always preferred. (N.C.)

  15. Antidepressants and testicular cancer: cause versus association.

    Andrade, Chittaranjan

    2014-03-01

    A data mining study that examined associations between 105 drugs and 55 cancer sites found significant associations between 2 selective serotonin reuptake inhibitors (fluoxetine and paroxetine) and testicular cancer. The study suggested several reasons why these associations merited further investigation. A later study tested specific relationships between 12 antidepressant drugs and testicular cancer and subtypes thereof; whereas significant relationships were again found, these disappeared after adjusting for confounding variables. These 2 studies are educative because they illustrate how false-positive results can easily arise in exploratory research and how confounding may be responsible for statistically significant relationships in study designs that are not randomized controlled trials. PMID:24717391

  16. Testicular and Paratesticular Neoplasms in Old Patients

    Naseer D. Choudhary,S.Manzoor Kadri ,Reyaz A Tasleem, Ruby Reshi,Syed Besina, Quarrat A Choudhary

    2003-04-01

    Full Text Available Testicular and Para testicular tumours from 27 patients aged 60-85 yrs. were assessed with respectto histological types. The tumours ofgerm cell origin were 15 in number (55.5% and non germ celltumours were 12 in number (44.5%. There were 13 cases of seminoma and 2 cases ofmixed genncell tumour. Among non germ cell type, 7 were Non-Hodgkin's Lymphoma, 2 were leiomyosarcoma,2 were metastatic deposits of adenocarcinoma and 1 was of adenomatoid tumour of epididymis.

  17. Testicular dysgenesis syndrome and Leydig cell function

    Joensen, U.N.; Jorgensen, N.; Rajpert-De, Meyts E.;

    2008-01-01

    Fertility among human beings appear to be on the decline in many Western countries, and part of the explanation may be decreasing male fecundity. A hypothesis has been put forward that decreasing semen quality may be associated with a testicular dysgenesis syndrome (TDS), a spectrum of disorders...... originating in early foetal life. TDS comprises various aspects of impaired gonadal development and function, including testicular cancer. A growing body of evidence, including animal models and research in human beings, points to lifestyle factors and endocrine disrupters as risk factors for TDS. We present...

  18. Probability to retrieve testicular spermatozoa in azoospermic patients

    H.-J.Glander; L.-C.Horn; W.Dorschner; U.Paasch; J.Kratzsch

    2000-01-01

    Aim: The degree of probability to retrieve spermatozoa from testicular tissue for intracytoplasmic sperm injection into oocytes is of interest for counselling of infertility patients. We investigated the relation of sperm retrieval to clinical data and histological pattern in testicular biopsies from azoospermic patients. Methods: In 264 testicular biopsies from 142 azoospermic patients, the testicular tissue was shredded to separate the spermatozoa, histological semi - thin sections of which were then evaluated using Johnsen score. Results: The retrieval of spermatozoa correlated significantly ( P 18 U/L, testicular volume < 5 mL, mean Johnsen score<5, and maximum Johnsen score < 7.

  19. Carcinoma epidermoide do pênis: estudo clínico-patológico de 34 casos Squamous cell carcinoma of the penis: clinicopathologic study of 34 cases

    Fabiana Braga França Wanick; Tullia Cuzzi Teichner; Rosane Silva; Mônica Maria Ferreira Magnanini; Lucia Maria Soares de Azevedo

    2011-01-01

    FUNDAMENTOS: No Brasil, a incidência do câncer do pênis é de 8,3 casos/100.000 habitantes, contrastando com 0,7 na Europa e nos Estados Unidos. Em 95% dos casos, trata-se do carcinoma epidermoide. Em geral, é diagnosticado tardiamente. OBJETIVOS: Descrever as características clínico-patológicas do carcinoma epidermoide do pênis, registradas no Hospital entre 1978 e 2004. MÉTODOS: Estudo observacional transversal. Incluíram-se os casos de carcinoma epidermoide do pênis, confirmados histologica...

  20. Tumores testiculares na infância Testicular tumors in childhood

    Roni Leonardo Teixeira

    2009-02-01

    Full Text Available Testicular and paratesticular prepuberal tumors are rare. They represent around 1% of the total of tumors of infancy. They subdivide in 2 groups: germ cells tumors and non germ cells tumors, being able to occur in all the ages, and about 75% are malignant, and about 19% of these they present metastasis. The tumors of germ cells tumors represent 60 75% of the tumors testiculars in infancy, having as main example the yolk sac tumor (65% of the neoplasms, followed for teratomas (14%; although some works to exist where teratoma, if presents as most common .The non germ cells tumors include the Leydig cell tumor and Sertoli cell tumor. The Leydig cell tumor, are most frequent between the non germ cells tumors testicular. This review article on epidemiology, diagnosis and treatment of to testicular and to paratesticular tumors in child.

  1. Prognostic role of p53 protein expression in epidermoid carcinoma of the anal canal

    Purpose: To assess the prognostic significance of p53 protein expression in patients with primary epidermoid carcinoma of the anal canal managed by radiation therapy (XRT), 5-fluorouracil (5-FU), and mitomycin C (MMC). Methods and Materials: From January 1991 to December 1993, 58 consecutive patients with primary epidermoid carcinoma of the anal canal were treated in a prospectively designed protocol of XRT (24 Gy/12--3((1)/(2)) wk split--28 Gy/14) and concurrent 5-FU (1000 mg/m2/day 1-4) and MMC (10 mg/m2 day 1) of each cycle of XRT. Paraffin-embedded tumor samples were unavailable in 9 patients, leaving 49 patients in the study. Expression of p53 protein was studied using immunohistochemistry and quantified as percent tumor nuclei showing positive staining. Actuarial survival and disease-free survival (DFS) rates were estimated by the Kaplan-Meier method, and compared using the log-rank test. A Cox proportional hazard model was used for the multivariable analysis. Results: There were 6 T1, 26 T2, 7 T3, and 10 T4 lesions. Primary tumor sizes ranged from 1-15 cm with a median of 4 cm. There were 6 patients with nodal metastases. Median follow-up was 4.5 years. Positive nuclear immunostaining for p53 was observed in 40 of 49 patients. The median percent positive staining was 5%, with 13, 9, and 18 patients showing staining in <5%, 5 to <10%, and 10-50% of tumor nuclei respectively. There was no correlation of percent p53 staining with gender, age, tumor stage, size, or histology. Local, regional, and distant failures were observed in 12, 2, and 2 patients respectively. The 5-yr survival and DFS were 84% and 64% respectively. In univariate analysis, the only prognostic variable for survival was gender. For DFS, advanced T category and large tumor size were predictive of poor DFS. In multivariate analysis, poor DFS was associated with high T category (p = 0.0008), basaloid histology (p = 0.001), male gender (p = 0.002), and increasing percent of p53 protein expression

  2. Testicular function in boys after chemotherapy and/or testicular irradiation for acute leukemia and malignant lymphoma

    Testicular function was investigated by testicular biopsy, testicular volume, testosterone and LH-RH test in 16 prepubertal boys with 15 cases of acute leukemia and one case of malignant lymphoma after chemotherapy and/or testicular irradiation. One of 2 cases who had infiltrated in testes received irradiation at onset. With another 2 cases, testis was resected at testicular relapse and irradiated on opposite side. All continued complete remission for 1-9 years after cessation of chemotherapy. Basal levels of serum testosterone, FSH and LH were normal in 13 cases of unirradiated group recently but spermatogonia in testicular biopsy specimen decreased on cessation of chemotherapy in 8 cases. Primary gonadal dysfunction was detected in 3 cases of irradiated group. And so testicular irradiation induced damage of tubular system and Leydig cell function. It is necessary to follow up about sexual maturation. (author)

  3. Simultaneous acute appendicitis with right testicular torsion

    Tanveer Akhtar

    2012-01-01

    Full Text Available We present a child with both acute appendicitis and torsion of the right testis presenting at the same time. Testicular torsion possibly occurring due to vomiting in acute appendicitis so far has not been reported in the literature.

  4. Quality of Life of Testicular Cancer Survivors

    Fleer, Joke

    2006-01-01

    Men who are diagnosed with testicular cancer are generally young. As a consequence of the treatment they receive nowadays, they are likely to cure from the disease, even when they have metastases. This means that they have to live with possible short- and long-term sequel of diagnosis and treatment

  5. Is Sedentary Lifestyle Associated With Testicular Function?

    Priskorn, Lærke; Jensen, Tina Kold; Bang, Anne Kirstine;

    2016-01-01

    Based on cross-sectional data on 1,210 healthy young Danish men, we investigated whether sedentary lifestyle was associated with testicular function (semen quality and reproductive hormones) independent of physical activity. The men were invited to participate in the study between 2008 and 2012, ...

  6. Aesthetic plastic correction of incomplete testicular feminization.

    Hinderer, U T

    1979-12-01

    Surgery was performed for feminization of ambiguous (male) external genitalia in 1973 on a patient with incomplete testicular feminization (familial male hermaphroditism of mixed variety). Rhinoplasty and augmentation of the chin, the malar region, the breasts were also performed not only to improve the patient's sexual role but to enhance the aesthetic appearance, as an aid in better phychosocial adaptation. PMID:24173991

  7. Surveillance in stage I testicular cancer

    Daugaard, Gedske; Petersen, Peter Meidahl; Rørth, Mikael

    2003-01-01

    Treatment results on 695 stage I testicular cancer patients followed with surveillance are described. Seminoma (SGCT) was present in 394 patients and nonseminoma (NSGCT) in 301 patients. Relapses were detected in 155 patients (22%), in 69 patients with SGCT (17%) and 86 with NSGCT (29%). In...

  8. TREATMENT FOR STAGE I TESTICULAR SEMINOMA

    E. A. Burova

    2014-07-01

    Full Text Available Overall survival is about 100% in patients with stage I germinogenic testicular tumors after orchifuniculectomy, which is achieved, by applying alternative adjuvant approaches. The use of approaches, such as a follow-up, chemo- and radiotherapy, may be recommended in seminoma. The paper shows the advantages and disadvantages of these methods.

  9. Microdissection testicular sperm extraction: an update

    Ali A Dabaja; Peter N Schlegel

    2013-01-01

    Patients with non-obstructive azoospermia (NOA) were once considered to be infertile with few treatment options due to the absence of sperm in the ejaculate.In the last two decades,the advent of intracytoplasmic sperm injection (ICSI),and the application of various testicular sperm retrieval techniques,including fine needle aspiration (FNA),conventional testicular sperm extraction (TESE) and microdissection testicular sperm extraction (micro-TESE) have revolutionized treatment in this group of men.Because most men with NOA will have isolated regions of spermatogenesis within the testis,studies have illustrated that sperm can be retrieved in most men with NOA,including Klinefelter's syndrome (KS),prior history of chemotherapy and cryptorchidism.Micro-TESE,when compared with conventional TESE has a higher sperm retrieval rate (SRR) with fewer postoperative complications and negative effects on testicular function.In this article,we will compare the efficacy of the different procedures of sperm extraction,discuss the medical treatment and the role of testosterone optimization in men with NOA and describe the micro-TESE surgical technique.Furthermore,we will update our overall experience to allow counseling on the prognosis of sperm retrieval for the specific subsets of NOA.

  10. The Correlation between Ultrasound Testicular Volume and Conventional Semen Parameters in Albanian Subfertile Males

    Adrian Kristo

    2014-09-01

    CONCLUSION: Testicular volume has a direct correlation with semen parameters and the critical total testicular volume indicating normal testicular function is approximately 26.6 ml (the mean testicular volume 13.3 ml. The measurement of testicular volume can be helpful for assessing fertility at the initial physical examination.

  11. Pheophorbide a mediated photodynamic therapy against human epidermoid carcinoma cells (A431)

    Chen, Yi-Chun; Li, Wen-Tyng

    2011-02-01

    The objective of this study was to characterize the death mechanism of human epidermoid carcinoma cells (A431) triggered by photodynamic therapy (PDT) with pheophorbide a. First of all, significant inhibition on the survival of A431 cells (N-Acetyl cysteine prevented ROS production and increased cell survival thereafter. The decrease in cellular ATP level was also observed at 6 hrs after PDT. Typical apoptotic cellular morphology and a collapse of mitochondrial membrane potential occurred after PDT. The loss of mitochondrial membrane potential led to the release of cytochrome c from the mitochondria to the cytosol, followed by activation of caspase-9 and caspase-3. The activation of caspase-3 resulted in poly(ADP-ribose) polymerase (PARP) cleavage in A431 cells, followed by DNA fragmentation. In conclusion, the results demonstrated that pheophorbide a possessed photodynamic action against A431 cells, mainly through apoptosis mediated by mitochondrial intrinsic pathway triggered by ROS.

  12. Epidermoids and dermoids of the calvarian bones in early childhood: Their behaviour in the growing skull

    Thirteen out of 25 cystic lesions of the infantile skull, radiographically classified as epidermoids or dermoids of the calvarian bones, disappeared spontaneously during early childhood. A further six lesions showed involution. In all, 19/25 lesions were involutive. In no case did we find an enlargement which could be attributed with certainly, to growth after the age of 3 years. These findings strongly support the opinion of Faure that by far most of these lesions are non-evolutive and generally do not need surgical treatment. Only lesions which do persist beyond the third year of life and grow continuously or begin to grow again need to be operated. Thus, we recommend a conservative attitude and a radiographic follow-up at long intervals. (orig.)

  13. [Laryngeal epidermoid carcinoma in a young adult without risk factors: a case report].

    M'barek, Basma; Gargouri, W; Maalej, M

    2005-08-01

    Head and neck carcinomas are rare in young patients without a history of tobacco consution, tho two classical risk factors. Our report is about 20 year-old patient without a history exosure to radiations or of alcohol / tobacco consumption, who presented with repeated episodes of dysphonia that didn't improve under medical treatment. Endoscopy showed a fungating hemilaryngeal lesion with a histology of epidermoid carcinoma stage T3N0. The patient initially 3 courses of cisplatin-5 fluorouracil resulting in a 90% objective response, followed by a loco-regional radiotherapy. 36 months after the diagnosis and 24 after the end of therapy, the patient is still alive and in complete remission. PMID:16238282

  14. Differentiation of testicular diseases via dynamic MRT

    The present study aimed at resolving whether dynamic MRT can improve diagnostic relevance in diseases of the testes compared with conventional spin echo images. The testes of 20 healthy volunteers and of 16 patients of the Department of Urology of the University of Bonn were examined by means of MR tomography. Within 12 hours after MR tomography the patients were surgically explored, biopsied and if necessary orchiectomised. Results obtained with the volunteers were uniform and well reproducible, independent of external influences. On comparing the maximal enhancement curves of the examined various testicular tumors with the standard values established by examining the healthy volunteers, the curves obtained with the malignant testicular tumors were always clearly above the chosen confidence range of 3 standard deviations so that malignancy diagnosis was easy. However, the degree of maximal enhancement did not enable us to arrive at a conclusion in respect of the tumor type or the degree of malignancy. The greatest enhancement occurred with the tumor of Sertoli's cell which could thus be clearly differentiated against the other malignant testicular tumors. Due to masking of the gadolinium effect by haemosiderin deposits, haemorrhagica in the tumor tissue should be excluded by means of T2-weighted spin echo sequences before following up a suspicion of malignant testicular tomor. Benign intratesticular changes could be safely separated from malignant findings by means of the maximal enhancement curve lying in the normal range or below the curve of the volunteers. As with other organs, dynamic MR tomography yields definitely more and better information than conventional MR tomography also in the diagnosis of testicular tumours. However, these ''pros'' do not offset the ''cons'' of high costs of such examinations. (orig.)

  15. Colloidal cyst of the third ventricle. Case presentation Quiste coloide del tercer ventrículo. Presentación de un caso

    Joan O Rojas Fuentes

    2009-09-01

    Full Text Available

    Colloidal cysts are congenital intracranial benign lesions of the anterior superior portion of the third ventricle. They represent between the 0,2 and 2 % of all the intracranial tumours and represent the 15 or 20 % of all the intraventricular masses. They become symptomatic during the adolescence or early adulthood and start normally with migraine or symptoms of intracranial hypertension causing obstructive hydrocephaly. We present the case of a teenager of 18 years of age with history of migraine after two years and the symptoms worsened in intensity and frequency including vomiting and bilateral paresthesia; the diagnosis was obstructive hydrocephaly with colloidal cyst of the third ventricle. An appropriate practice was adopted due to the uncertain diagnosis in order to avoid neurological damage and death. We discussed the main characteristics of the colloidal cyst, its clinical presentation and radiological characteristics and we performed.

    Los quistes coloides son lesiones intracraneales congénitas benignas, de la porción antero-superior del tercer ventrículo. Suponen del 0,2 al 2 % de todos los tumores intracraneales y representan del 15 al 20 % de todas las masas intraventriculares. Comienzan a ser sintomáticos en la adolescencia o edad adulta temprana, generalmente con manifestaciones de cefalea o síntomas de hipertensión intracraneal al provocar hidrocefalia obstructiva. Se presenta una adolescente de 18 años con historia de cefalea de 2 años de evolución, cuyos síntomas fueron empeorando en intensidad y frecuencia, acompañados de vómitos y parestesias bilaterales; se le diagnosticó hidrocefalia obstructiva con quiste coloide del tercer ventrículo. Ante la sospecha del diagnóstico se tomó una conducta adecuada, para evitar el deterioro neurológico y la muerte. Se discutieron las principales características del quiste coloide, su cuadro clínico y radiológico.

  16. Epidemiology of prolonged testicular infections with bovine viral diarrhea virus.

    Givens, M Daniel; Riddell, Kay P; Edmondson, Misty A; Walz, Paul H; Gard, Julie A; Zhang, Yijing; Galik, Patricia K; Brodersen, Bruce W; Carson, Robert L; Stringfellow, David A

    2009-10-20

    Previously, bovine viral diarrhea virus (BVDV) had been found in prolonged testicular infections following acute infection of immunocompetent bulls. The primary purpose of this research was to evaluate the production and maintenance of prolonged testicular infections after exposure to BVDV of seronegative bulls in varying circumstances. The secondary objective was to initiate assessment of the potential for transmission of BVDV via semen of bulls exhibiting a prolonged testicular infection. In total, 10 research trials were conducted. The first trial examined the duration of detectable virus in semen after intranasal inoculation of peri-pubertal bulls. The second to fifth trials examined the potential for prolonged testicular infections resulting from natural exposure of seronegative bulls to persistently infected heifers. In the last five trials, the potential for viral transmission from bulls exhibiting prolonged testicular infections to a small number of exposed animals (n=28) was evaluated. Results of this research demonstrated that prolonged testicular infections could result in detection of viral RNA in semen for 2.75 years with infectious virus grown from testicular tissue 12.5 months after viral exposure. A type 1b strain of BVDV caused prolonged testicular infection after natural exposure of seronegative bulls to a persistently infected heifer. However, transmission of BVDV to susceptible animals was not detected in the final five trials of this research. In conclusion, BVDV can persist in testicular tissue after acute infection for several years, but the potential for viral transmission from these prolonged testicular infections appears to be low. PMID:19473788

  17. Distensión abdominal y edemas por quiste del cordón espermático Abdomina distention and edema due to spermatic cord cyst

    Guillermo A. Keller; Cecilia Sessa

    2006-01-01

    La distensión abdominal es un síntoma común, siendo en general la presentación inicial de enfermedades sistémicas o desórdenes gastrointestinales. Otras causas son infrecuentes. Los quistes del cordón espermático son poco frecuentes, pero aún más su ubicación intraabdominal, su tamaño habitual es insuficiente para producir distensión. El paciente presentado en este caso es un varón con criptorquidia bilateral admitido por distensión abdominal, interpretada inicialmente como síndrome ascítico ...

  18. Investigación experimental de la equinococosis canina a partir de quiste hidatídico de origen porcino en México

    Zuñiga-A Ismael; Jaramillo-A Carlos J; Martínez-M José J; Cárdenas-L Jorge

    1999-01-01

    OBJETIVO: Para evaluar la infección y obtener el estado adulto del cestodos, se buscó reproducir la equinococosis en perros a partir de quiste hidatídico de origen porcino. MÉTODOS: Se formaron 2 grupos, uno de 5 y otro de 3 perros, a cada animal del grupo experimental se le dió 2 g de membrana germinativa de quíste hidatídico fértil por vía oral, el segundo grupo fue testigo. Ambos grupos fueron evaluados clínica, serológica y parasitológicamente, en el grupo experimental se sacrificó un ani...

  19. A novel method for orthotopic testicular transplantation in rats

    ZHANG Wei-xing; TAN Fu-qing; WANG Jia-xiang; CHEN Zhao-dian; ZHENG Shu

    2005-01-01

    @@ Rat testis transplantation with a segment of donor abdominal aorta end-to-side anastomosed to recipient's abdominal aorta was first reported by Lee.1 But thrombus was formed in the donor abdominal aorta segment. Goldsein2 and Lee3 improved this technique using end-to-side anastomosis of an aortic patch with the testicular artery to the recipient's aorta and the testicular vein was anastomosed to the vena cava of the recipient. With this method, the animal with the testicular artery and vein paralleling and originating no more than 4 mm apart is considered a suitable donor, which is scarce because of the variability of testicular vessels. This problem limits the wide use of testicular transplantation in rats. Based on these findings, we established a novel testicular transplantation model which was recreated as closely as possible to the normal vascular anatomy of the testis in rats. The functional activities of these transplants were also presented.

  20. Reconstrucción de defectos óseos causados por quistes residuales de los maxilares con hidroxiapatita porosa coralina hap-200

    Juan Carlos Quintana-Díaz

    2014-01-01

    Full Text Available Se presentan los resultados obtenidos como parte de la extensión de las aplicaciones clínicas de la Hidr oxiapatita Coralina ® HAP - 200 como biomaterial de implante para la regeneración del tejido óseo en la región maxilofacial. En este caso, se emplea en forma de gránulos para la restauración de defectos óseos causados por quistes residuales a 24 pacientes (17 2 quistes siguiendo las indicaciones y normas establecidas para el uso de este tipo de material. La evaluación clínica y radiográfica postoperatoria se realizó a los tres días, siete días, treinta días, tres meses, seis meses y al año de operados los paci entes, teniendo en cuenta la presencia e intensidad del dolor, eritema, edema, infección o exposición del biomaterial de implante según lo indicado en el protocolo de evaluación de estos productos. Los estudios clínicos y radiográficos longitudinales de lo s pacientes en el primer año después de implantados confirman los excelentes resultados en cuanto a la tolerancia y biocompatibilidad del producto, lográndose una excelente restauración estética. Como en estudios anteriores, en ningún caso se produjeron re acciones adversas al biomaterial. Los resultados confirman que la hidroxiapatita Coralina® HAP - 200 es un excelente biomaterial de sustitución ósea por su demostrada biocompatibilidad, osteointegración y no se reabsorbe apreciablemente en los primeros 12 me ses de implantado.

  1. Purification of high-molecular-weight subfraction from porcine skin inhibiting proliferation of A431 human carcinoma epidermoid cells.

    Belova, O V; Sergienko, V I; Arion, V Ya; Lukanidina, T A; Moskvina, S N; Zimina, I V; Borisenko, G G; Lutsenko, G V; Grechikhina, M V; Kovaleva, E V; Klyuchnikova, Zh I

    2014-07-01

    Subfraction with a molecular weight >250 kDa isolated from porcine skin and inhibiting the proliferation of A431 human carcinoma epidermoid cells was purified by DEAE 32 anion exchange chromatography with NaCl concentration step-gradient. The effects of the initial subfraction and fractions obtained by separation in DEAE 32 on the proliferation of A431 human carcinoma epidermoid cells were studied in vitro in two tests (MTT and fluorescent test). The more sensitive fluorescent test showed the highest inhibitory activity of fraction No. 2 released from the column at 0.15 M NaCl. One major protein component and a series of minor protein components were detected in this fraction by vertical PAAG-SDS electrophoresis. PMID:25070165

  2. Testicular chloroma in a nonleukemic infant.

    Armstrong, Michael B; Nafiu, Olubukola O; Valdez, Riccardo; Park, John M; Williams, James A; Wechsler, Daniel S

    2005-07-01

    Extramedullary myeloid cell tumors (EMCT) are localized collections of immature myeloid cells that occur outside of the bone marrow. Usually observed concurrently with bone marrow disease, EMCT also may occur in the absence of overt marrow leukemia. In this report, we describe an infant with a testicular mass that was identified as an EMCT after orchiectomy. Unlike the only previously reported case of infantile testicular chloroma, this patient did not exhibit bone marrow disease at diagnosis. Because systemic chemotherapy is considered to be superior to local control (surgery, radiation therapy), the patient was treated with intensively timed induction chemotherapy followed by 3 cycles of maintenance treatment (according to CCG protocol #2891) but no radiation therapy. The patient remains disease-free 18 months after diagnosis. PMID:16012331

  3. A Rare Complication of Brucellosis: Testicular Abscess

    Ümit Gul

    2016-01-01

    Full Text Available Brucellosis is a zoonosis caused by Brucella species. Brucella epididymo-orchitis had been reported in up to 20% of patients with brucellosis. This case was a male patient who developed Brucella epidiymo-orchitis and testicular abscess. He had fever, arthralgia and his right epididymis and right testicle were enlarged and tender. Ultrasound evaluation showed hypertrophy of the right epididymis and testis and moreover hypoechoic area within the testis. Brucella serology was positive and the patient did not respond completely to treatment with streptomycin, doxycycline, and rifampicina. Unilateral orchidectomy was decided. In areas where brucella infection is endemic brucella epididymo-orchitis should be considered in the differential diagnosis. Effective and rapid treatment is important. It should be noted that these patients may develop testicular abscess.

  4. [Relationship between phthalates and testicular dysgenesis syndrome].

    Chen, Guo-Rong; Dong, Lei; Ge, Ren-Shan; Hardy, Matthew P

    2007-03-01

    Recent epidemiological evidence demonstrates that boys born to women exposed to phthalates during pregnancy have an increased incidence of cryptorchidism, hypospadias, testicular cancer and spermatogenic dysfunction, which are collectively referred to as testicular dysgenesis syndrome (TDS). TDS may be attributed to the dysfunction of Leydig cells and Sertoli cells during their differentiation after exposure to phthalates in utero. Fox example, Leydig cell functions are significantly affected by phthalates, leading to the decrease of two Leydig cell products--insulin-like growth factor 3 (INSL3) and testosterone, which are critical factors for testis descent. The disorientation of Leydig cells and Sertoli cells in the adult testis may be the cause of spermatogenic dysfunction. PMID:17393778

  5. A Rare Cause of Testicular Metastasis: Upper Tract Urothelial Carcinoma

    Manav, Alper Nesip; Kazan, Ercan; Ertek, Mehmet Şirin; Amasyalı, Akın Soner; Çulhacı, Nil; Erol, Haluk

    2014-01-01

    Metastatic testicular cancers are rare. Primary tumor sources are prostate, lung, and gastrointestinal tract for metastatic testicular cancers. Metastasis of urothelial carcinoma (UC) to the testis is extremely rare. Two-thirds of upper tract urothelial carcinoma (UTUC) is of invasive stage at diagnosis and metastatic sites are the pelvic lymph nodes, liver, lung, and bone. We report a rare case of metastatic UTUC to the testis which has not been reported before, except one case in the literature. Testicular metastasis of UC should be considered in patients with hematuria and testicular swelling. PMID:25120937

  6. Testicular dysgenesis syndrome and Leydig cell function

    Joensen, Ulla Nordström; Jørgensen, Niels; Rajpert-De Meyts, Ewa; Skakkebaek, Niels Erik

    2008-01-01

    Fertility among human beings appear to be on the decline in many Western countries, and part of the explanation may be decreasing male fecundity. A hypothesis has been put forward that decreasing semen quality may be associated with a testicular dysgenesis syndrome (TDS), a spectrum of disorders ...... our view of the emerging role of Leydig cell dysfunction with subsequent decreased testosterone levels in the pathogenesis of TDS....

  7. Comet assay on mice testicular cells

    Anoop Kumar Sharma

    2015-01-01

    Heritable mutations may result in a variety of adverse outcomes including genetic disease in the offspring. In recent years the focus on germ cell mutagenicity has increased and the “Globally Harmonized System of Classification and Labelling of Chemicals (GHS)” has published classification criteria for germ cell mutagens (Speit et al., 2009). The in vivo Comet assay is considered a useful tool for investigating germ cell genotoxicity. In the present study DNA strand breaks in testicular cel...

  8. Prenatal and familial associations of testicular cancer.

    Swerdlow, A J; Huttly, S. R.; Smith, P.G.

    1987-01-01

    In a case-control study of testis cancer 259 cases with testicular cancer, 238 controls treated at radiotherapy centres and 251 non-radiotherapy hospital in-patient controls were interviewed about some possible prenatal and familial risk factors for the tumour. For firstborn men, the risk of testis cancer increased significantly according to maternal age at the subject's birth, and this effect was most marked for seminoma. The association with maternal age was not apparent for cases other tha...

  9. Polyorchidism with presumed contralateral intrauterine testicular torsion

    Leodoro, B.M.; Beasley, S. W.; Stringer, M. D.

    2014-01-01

    INTRODUCTION: Polyorchidism was first described by Blasius in 16701 during a routine autopsy. We report a child with unilateral polyorchidism and a contralateral absent testis, a combination not reported previously. PRESENTATION OF CASE: A 2-year-old boy was referred to the outpatient clinic with an impalpable left testis. At laparoscopy, the left vas deferens and testicular vessels ended blindly proximal to a closed internal ring. No gonadal tissue was identified. On the right side, a sin...

  10. Testicular Compromise due to Inguinal Hernia

    eutermoser, morgan p; Nordenholz, Kristen

    2012-01-01

    A 34-year-old male presented to the emergency department with a 3-hour complaint of pain in the rightlower quadrant and right testicle. He stated that his pain began suddenly while standing at work. Onphysical examination, he had a small, firm, unreducible bulge in his right inguinal canal and an enlargedright scrotum. The patient was placed in trendelenburg position; intravenous fentanyl, valium, anddilaudid were administered; and surgery consult was obtained. A testicular ultrasonogram (Fig...

  11. Knockdown of asparagine synthetase by RNAi suppresses cell growth in human melanoma cells and epidermoid carcinoma cells.

    Li, Hui; Zhou, Fusheng; Du, Wenhui; Dou, Jinfa; Xu, Yu; Gao, Wanwan; Chen, Gang; Zuo, Xianbo; Sun, Liangdan; Zhang, Xuejun; Yang, Sen

    2016-05-01

    Melanoma, the most aggressive form of skin cancer, causes more than 40,000 deaths each year worldwide. And epidermoid carcinoma is another major form of skin cancer, which could be studied together with melanoma in several aspects. Asparagine synthetase (ASNS) gene encodes an enzyme that catalyzes the glutamine- and ATP-dependent conversion of aspartic acid to asparagine, and its expression is associated with the chemotherapy resistance and prognosis in several human cancers. The present study aims to explore the potential role of ASNS in melanoma cells A375 and human epidermoid carcinoma cell line A431. We applied a lentivirus-mediated RNA interference (RNAi) system to study its function in cell growth of both cells. The results revealed that inhibition of ASNS expression by RNAi significantly suppressed the growth of melanoma cells and epidermoid carcinoma cells, and induced a G0/G1 cell cycle arrest in melanoma cells. Knockdown of ASNS in A375 cells remarkably downregulated the expression levels of CDK4, CDK6, and Cyclin D1, and upregulated the expression of p21. Therefore, our study provides evidence that ASNS may represent a potential therapeutic target for the treatment of melanoma. PMID:25858017

  12. Induction of apoptosis and antiproliferative activity of naringenin in human epidermoid carcinoma cell through ROS generation and cell cycle arrest.

    Md Sultan Ahamad

    Full Text Available A natural predominant flavanone naringenin, especially abundant in citrus fruits, has a wide range of pharmacological activities. The search for antiproliferative agents that reduce skin carcinoma is a task of great importance. The objective of this study was to analyze the anti-proliferative and apoptotic mechanism of naringenin using MTT assay, DNA fragmentation, nuclear condensation, change in mitochondrial membrane potential, cell cycle kinetics and caspase-3 as biomarkers and to investigate the ability to induce reactive oxygen species (ROS initiating apoptotic cascade in human epidermoid carcinoma A431 cells. Results showed that naringenin exposure significantly reduced the cell viability of A431 cells (p<0.01 with a concomitant increase in nuclear condensation and DNA fragmentation in a dose dependent manner. The intracellular ROS generation assay showed statistically significant (p<0.001 dose-related increment in ROS production for naringenin. It also caused naringenin-mediated epidermoid carcinoma apoptosis by inducing mitochondrial depolarization. Cell cycle study showed that naringenin induced cell cycle arrest in G0/G1 phase of cell cycle and caspase-3 analysis revealed a dose dependent increment in caspase-3 activity which led to cell apoptosis. This study confirms the efficacy of naringenin that lead to cell death in epidermoid carcinoma cells via inducing ROS generation, mitochondrial depolarization, nuclear condensation, DNA fragmentation, cell cycle arrest in G0/G1 phase and caspase-3 activation.

  13. Cryopreservation of canine ovarian and testicular fibroblasts.

    Yu, Il-Jeoung; Leibo, S P; Songsasen, Nucharin; Dresser, Betsy L; Kim, In-Shik

    2009-01-01

    To derive a practical procedure to store canine somatic cells, fibroblasts isolated from testicular or ovarian tissues were cryopreserved in 1.2 M ethylene glycol or in 1.2 M dimethylsulfoxide prepared in Dulbecco's Modified Eagle Medium as cryoprotectants, and were frozen either in plastic straws or vials. Thawed cells were cultured for 24 hr at 38.5 degree C in a humidified atmosphere of 5 percent CO2 95 percent air, and then their membrane integrity was assayed with a double fluorescent stain, Fertilight. In addition, frozen-thawed fibroblasts were cultured for 4 days, and then their functional survival was measured after staining small colonies with trypan blue. After freezing and thawing, membrane integrity of testicular fibroblasts was 55-70 percent and functional survival ranged from 20-40 percent. With frozen-thawed ovarian cells, the average membrane integrity was 55-75 percent and the average functional survival was 35-40 percent. When frozen in ethylene glycol, functional survival of ovarian fibroblasts was significantly higher than that of testicular cells (P less than 0.05). These methods should prove useful to preserve cells collected from canids in the wild. PMID:19750243

  14. Comet assay on mice testicular cells

    Anoop Kumar Sharma

    2015-05-01

    Full Text Available Heritable mutations may result in a variety of adverse outcomes including genetic disease in the offspring. In recent years the focus on germ cell mutagenicity has increased and the “Globally Harmonized System of Classification and Labelling of Chemicals (GHS” has published classification criteria for germ cell mutagens (Speit et al., 2009. The in vivo Comet assay is considered a useful tool for investigating germ cell genotoxicity. In the present study DNA strand breaks in testicular cells of mice were investigated. Different classes of chemicals were tested in order to evaluate the sensitivity of the comet assay in testicular cells. The chemicals included environmentally relevant substances such as Bisphenol A, PFOS and Tetrabrombisphenol A. Statistical power calculations will be presented to aid in the design of future Comet assay studies on testicular cells. Power curves were provided with different fold changes in % tail DNA, different number of cells scored and different number of gels (Hansen et al., 2014. An example is shown in Figure 1. A high throughput version of the Comet assay was used. Samples were scored with a fully automatic comet assay scoring system that provided faster scoring of randomly selected cells.

  15. Testicular Histomorphometric Evaluation of Zebu Bull Breeds

    Paulo Antônio Terrabuio Andreussi

    2014-12-01

    Full Text Available The objective of this study was to evaluate the quantitative histology and testicular biometrics in zebu bulls of different breeds. Testicular fragments of Nelore (n=10, Polled Nelore (n=6, Gir (n=5, Guzerat (n=5 and Tabapuã bulls (n=5 were used. The fragments were perfusion-fixed in Karnovsky solution, embedded in glycol methacrylate and stained with toluidine blue-1% sodium borate. The Nelore animals had a higher tubular volumetric proportion (85.2% and greater height of the seminiferous epithelium (73.2 µm than the Gir, Guzerat and Tabapuã breeds. The Nelore animals also had a higher volumetric proportion of Leydig cells (5.2% than the Guzerat and Tabapuã breeds. There was no significant difference for any of these parameters between the Nelore and Polled Nelore breeds. The gonadosomatic index, seminiferous tubule diameter, cross-sectional area of the seminiferous tubule and tubule length (total length and length per gram of testicular parenchyma did not vary among the breeds studied. The morphometric parameters evaluated suggested that the genetic selection applied to the Nelore and Polled Nelore breeds improved the efficiency of spermatogenesis in these breeders.

  16. Testicular self-examination and testicular cancer: a cost-utility analysis.

    Aberger, Michael; Wilson, Bradley; Holzbeierlein, Jeffrey M; Griebling, Tomas L; Nangia, Ajay K

    2014-12-01

    The United States Preventive Services Task Force (USPSTF) has recommended against testicular self-examinations (TSE) or clinical examination for testicular cancer screening. However, in this recommendation there was no consideration of the significant fiscal cost of treating advanced disease versus evaluation of benign disease. In this study, a cost-utility validation for TSE was performed. The cost of treatment for an advanced-stage testicular tumor (both seminomatous and nonseminomatous) was compared to the cost of six other scenarios involving the clinical assessment of a testicular mass felt during self-examination (four benign and two early-stage malignant). Medicare reimbursements were used as an estimate for a national cost standard. The total treatment cost for an advanced-stage seminoma ($48,877) or nonseminoma ($51,592) equaled the cost of 313-330 benign office visits ($156); 180-190 office visits with scrotal ultrasound ($272); 79-83 office visits with serial scrotal ultrasounds and labs ($621); 6-7 office visits resulting in radical inguinal orchiectomy for benign pathology ($7,686) or 2-3 office visits resulting in treatment and surveillance of an early-stage testicular cancer ($17,283: seminoma, $26,190: nonseminoma). A large number of clinical evaluations based on the TSE for benign disease can be made compared to the cost of one missed advanced-stage tumor. An average of 2.4 to 1 cost benefit ratio was demonstrated for early detected testicular cancer versus advanced-stage disease. PMID:25103095

  17. Radiation therapy for epidermoid carcinoma of the anal canal, clinical and treatment factors associated with outcome

    Background and purpose: In recent years, treatment with combined chemotherapy and radiation has become the standard of care for epidermoid carcinoma of the anus. However, optimal radiotherapy techniques and doses are not well established. Materials and methods: During the period 1975-1997, 106 patients with epidermoid carcinoma of the anal canal underwent radiation therapy. Treatment policies evolved from radiation therapy alone or with surgery, to combined chemotherapy and radiation followed by surgery, to combined chemotherapy and radiation. Results: Overall 74% of patients were NED (no evidence of disease) at last follow-up. The most important clinical correlate with ultimate freedom from disease (includes the contribution of salvage surgery) was extent of disease. The 5-year ultimate freedom from disease was 87±5% for T1/T2N0, 78±10% for T3N0 (15% salvaged by surgery), and 43±10% for either T4N0 or any N+ lesions (P<0.001, Tarone-Ware). There was no difference between planned vs. expectant surgery (5-year ultimate NED: 67±11% planned surgery vs. 73±5% expectant surgery). The most important correlate with late toxicity was a history of major pelvic surgery (surgical vs. non-surgical group: P=0.013, Fisher's exact test, two-tailed summation). Thirty-three additional malignancies have been seen in 26 patients. The most common additional malignancies were gynecologic (nine cases), head and neck (six cases), and lung cancer (five cases). Conclusions: For T1/T2N0 disease, moderate doses of radiation combined with chemotherapy provided adequate treatment. T4N0 and N+ lesions are the most appropriate candidates for investigational protocols evaluating dose intensification. T3N0 tumors may also be appropriate for investigation; however, dose intensification may ultimately prove counterproductive if the cure rate is not improved and salvage surgery is rendered more difficult. The volume of irradiated small bowel should be minimized for patients who have a past

  18. Combination of radiotherapy and cetuximab for patients suffering from of an advanced and non operable epidermoid carcinoma of the ORL sphere: results and side effects; Association de radiotherapie et de cetuximab chez des patients atteints d'un carcinome epidermoide de la sphere ORL evolue non operable: resultats et effets secondaires

    Acevedo, C.; Valette, G.; Bouchekoua, M.; Marianowski, R.; Pradier, O. [CHU Morvan, 29 - Brest (France)

    2010-10-15

    The authors report a retrospective survey of a set of locally advanced epidermoid carcinomas treated by irradiation and cetuximab. They assessed the response to the treatment, the specific survival, and the global survival as well as the tolerance. The survey is based on 31 men and 5 women suffering from different stage 4 non-metastatic advanced epidermoid carcinomas of the ORL sphere. Short communication

  19. Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects

    Sharpe, R.M.; Skakkebæk, Niels Erik

    Reproductive disorders of newborn (cryptorchidism, hypospadias) and young adult males (low sperm counts, testicular germ cell cancer) are common and/or increasing in incidence. It has been hypothesized that these disorders may comprise a testicular dysgenesis syndrome (TDS) with a common origin in...

  20. Sexual dysfunctions in men treated for testicular cancer

    Rosendal, Susanne; Kristensen, Ellids; Giraldi, Annamaria G E

    2008-01-01

    Patients treated for testicular cancer have increased risk of ejaculatory, orgasmic and erectile dysfunction compared with healthy men. The underlying relations are unclear. This review describes sexual dysfunctions that are associated with various treatment modalities. One meta-analysis and 11...... understanding sexual dysfunctions in patients with testicular cancer....

  1. Epidermoid cyst in the cerebellopontine angle cistern presenting as trigeminal neuralgia

    This 29-year-old male had been suffering from left trigeminal neuralgia one year prior to admission. Admission was prompted by the development of pain in the third division of the left trigeminal nerve. Physical and neurological examinations were not remarkable except for the facial pain. The orbicularis oculi reflex showed delayed latency of R1 on the affected side. CT scans performed pre- and post-contrast enhancement revealed a low density area in the left cerebellopontine angle cistern. Metrizamide CT cisternography clearly revealed the margin of the lesion as the contrast media did not enter into the low density area. A left suboccipital craniectomy was performed. The trigeminal nerve was surrounded by a thin-capsulated mass and cholesteatoma materials. Histological diagnosis was epidermoid cyst. Since this surgical procedure, the trigeminal neuralgia has not recurred for one year. Without objective neurological deficits, it is difficult to distinguish symptomatic trigeminal from idiopathic neuralgia. Therefore, minor change of the orbicularis oculi reflex should help in objectively detecting dysfunction of the trigeminal nerve. Metrizamide CT cisternography is also useful in diagnosis of cystic lesions. (author)

  2. Induction chemotherapy and radiotherapy in loco-regionally advanced epidermoid carcinoma of the anal canal

    Purpose: To evaluate the efficacy of induction chemotherapy in combination with radiotherapy for treatment of loco-regionally advanced epidermoid anal carcinoma. Methods and Materials: Thirty-one patients diagnosed during the period 1989-1994 with loco-regionally advanced cancer of the anal canal (PHITmax ≥ 4 cm or T4 or N+) were treated with induction chemotherapy consisting of one to three courses of carboplatin (300-375 mg/m2 i.v.) and 5-fluorouracil [5,000 mg/(m2 x 120 h) i.v.] followed by external beam irradiation ± surgery. Results: The toxicity of the chemotherapy was low. Twenty-nine patients were tumor free after the primary therapy. Kaplan-Meier analyses were made for overall survival, tumor-specific survival, freedom from recurrence, preservation of sphincter, and event-free survival. For these end points the 5-year data were 67, 85, 80, 69, and 51%, respectively. Conclusion: The results are promising but a well-designed randomized trial is needed to further elucidate the role of induction chemotherapy in the treatment of loco-regionally advanced anal carcinoma

  3. Detection of Protein BCL2/JH Rearrangement in Epidermoid Carcinomas of Mouth and Pharynx

    Montovani, Jair

    2010-09-01

    Full Text Available Introduction: The BCL2 protein found in the internal mothocondrial membrana regulates the apoptosis preventing the programmed cell death. The translocation (14:18, detected in 70 to 85% of the follicular lymphoma, lead the super expression of BCL2 protein, by juxtaposition of BCL2 gene to the JH segment of the immunoglobulins' heavy chain gene. However, the found of the BCL2 expression in head and neck carcinoma are contradictious. Objective: To investigate the presence of the translocation (14:18 of the BCL2 gene in head and neck carcinoma. Method: Sixteen DNA samplers were examinated being 13 of squamous cells carcinoma (SCC and 3 of epidermoid (CE, y means of chain reaction of the polymerase (PCR. Results: The BCL2/JH rearrangement in 2 (15% of the CCE 13 cases and in none of the 3 cases of CE. The average of the frequency of molecules with rearrangement was 46,44x107. Was not observed association between the rearrangement presence and the exhibition to tobacco and alcohol (p=0, 6545. Conclusion: Different from the results found in follicular lymphoma, the presence of the translocation (14; 18 in head and neck carcinomas is not common and, when it occurs, it can be an occasional mutation not associated to exhibition to the tobacco and alcohol.

  4. Phosphorylation of chloroform soluble compounds in plasma membranes of human epidermoid carcinoma A431 cells

    This study investigated a possible role for the epidermal growth factor (EGF) receptor protein tyrosine kinase in phosphoinositide metabolism with plasma membrane vesicles from human epidermoid carcinoma (A431) cells. The authors found a novel chloroform-soluble product radiolabeled with [gamma-32P]ATP that did not migrate from the origin in the thin layer system designed to separate the phosphoinositides, appeared as a single band of Mr = 3500 on polyacrylamide gels in the presence of dodecyl sulfate, had an ultraviolet absorbance spectrum with a maximum at 275 nm and stained with Coomassie dye. Based on these properties this phosphorylation product is referred to as a proteolipid. The 32P label was not detected in phosphotyrosine [Tyr(P)], phosphoserine [Ser(P)] or phosphothreonine [Thr(P)] and was lost during acid or base hydrolysis. Phosphorylation of proteolipid was increased significantly by EGF, whereas phosphorylation of phosphatidic acid was decreased and labeling of phosphoinositides was unaffected. Thus, it appears that in A431 membranes the EGF receptor/kinase does not utilize phosphatidylinositol as a substrate, but does phosphorylate a membrane proteolipid

  5. Primary testicular mucinous cystadenoma: Case report and literature review.

    de Lima, Mário Maciel; de Lima, Mário Maciel; Granja, Fabiana

    2015-01-01

    Testicular mucinous cystadenomas are rare in urological practice, and their histogenesis, course and management are debated. We report a primary testicular mucinous cystadenoma in a 54-year old male who presented with left testicular swelling and pain. He denied having a history of cryptorchidism, testicular trauma, infections, urinary complaints, or febrile illnesses. He did not have diabetes, but was on treatment for hypertension. The patient underwent a left inguinal radical orchiectomy, and histological examination of the resected tumour confirmed a primary testicular mucinous cystadenoma. The patient had an uneventful recovery, and is being followed up. Conclusively, urologists need to maintain a high index of suspicion of these tumours and their differentiation from metastatic tumours to ensure optimal therapeutic outcomes. PMID:26600891

  6. Development and clinical application of a new testicular prosthesis

    Ye Ning; Zhikang Cai; Huixing Chen; Ping Ping; Peng Li; Zhong Wang; Zheng Li

    2011-01-01

    A new type of testicular prosthesis made of silastic with an elliptical shape to mimic a normal testis was developed by our team and submitted for patenting in China.The prosthesis was produced in different sizes to imitate the normal testis of the patient.To investigate the effects and safety of the testicular prosthesis,20 patients receiving testicular prosthesis implantation were recruited for this study.Follow-up after 6 months revealed no complications in the patients.All the patients answered that they were satisfied with their body image and the position of the implants,19 patients were satisfied with the size and 16 patients were satisfied with the weight.These results show that the testicular prosthesis used in this study can meet patient's expectations.Patients undergoing orchiectomy should be offered the option to receive a testicular prosthesis implantation.The dimensions and weight of the available prosthetic implants should be further addressed to improve patient satisfaction.

  7. Radiotherapy Treatment Planning for Testicular Seminoma

    Wilder, Richard B., E-mail: richardbwilder@yahoo.com [Department of Radiation Oncology, Moffitt Cancer Center, Tampa, FL (United States); Buyyounouski, Mark K. [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Efstathiou, Jason A. [Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA (United States); Beard, Clair J. [Department of Radiation Oncology, Dana-Farber/Brigham and Women' s Cancer Center, Boston, MA (United States)

    2012-07-15

    Virtually all patients with Stage I testicular seminoma are cured regardless of postorchiectomy management. For patients treated with adjuvant radiotherapy, late toxicity is a major concern. However, toxicity may be limited by radiotherapy techniques that minimize radiation exposure of healthy normal tissues. This article is an evidence-based review that provides radiotherapy treatment planning recommendations for testicular seminoma. The minority of Stage I patients who choose adjuvant treatment over surveillance may be considered for (1) para-aortic irradiation to 20 Gy in 10 fractions, or (2) carboplatin chemotherapy consisting of area under the curve, AUC = 7 Multiplication-Sign 1-2 cycles. Two-dimensional radiotherapy based on bony anatomy is a simple and effective treatment for Stage IIA or IIB testicular seminoma. Centers with expertise in vascular and nodal anatomy may consider use of anteroposterior-posteroanterior fields based on three-dimensional conformal radiotherapy instead. For modified dog-leg fields delivering 20 Gy in 10 fractions, clinical studies support placement of the inferior border at the top of the acetabulum. Clinical and nodal mapping studies support placement of the superior border of all radiotherapy fields at the top of the T12 vertebral body. For Stage IIA and IIB patients, an anteroposterior-posteroanterior boost is then delivered to the adenopathy with a 2-cm margin to the block edge. The boost dose consists of 10 Gy in 5 fractions for Stage IIA and 16 Gy in 8 fractions for Stage IIB. Alternatively, bleomycin, etoposide, and cisplatin chemotherapy for 3 cycles or etoposide and cisplatin chemotherapy for 4 cycles may be delivered to Stage IIA or IIB patients (e.g., if they have a horseshoe kidney, inflammatory bowel disease, or a history of radiotherapy).

  8. Epidermoid bronchogenic carcinoma in a 21 year old black man Carcinoma broncogénico epidermoide en un hombre de 21 años

    Dianelisa De La Hoz Rodríguez

    1999-01-01

    Full Text Available A 21 year cid black man, native from Chocó (Colombia, variously employed, who presented with a respiratory difficulty syndrome of two months of evolution, right pleuritic pain, congestive cardiac failure and systemic symptoms. A homogeneic white .grayish tumor measuring 8 by 10 cm with necrotic areas was found at necropsy. The tumor originated in the main bronchial tube of the lower and middle lobes of the right lung and invaded the entire pericardial vicinity forming a cuirass and causing tumoral constrictive pericarditis. Microscopic studies revealed a well differentiated squamous type bronchogenic carcinoma. Bronchogenic carcinomas are frequently associated with cigarette smoking. However, their incidente has increased among non. smokers, suggesting the possibility that there are other causal factors, such as atmospheric contaminants, genetic predisposition, diets deficient in vitamin A and carotene, presente of certain viruses and immunologic changes. Lung cancer constitutes 16% among the types of cancer suffered by men and 13% among women, it has its greatest incidente in groups between 40 and 70 years of age and only 1 to 5 percent of thecasesoccur in groupsunder theageofforty years. Hombre de 21 años de edad de raza negra, natural del Chocó (Colombia, quien ha desempeñado diversos oficios; presentó un síndrome de dificultad respiratoria de dos meses de evolución, dolor pleurítico derecho, insuficiencia cardíaca congestiva y síntomas sistémicos. En la necropsia se encontró una masa tumoral blanco-grisácea de 10 x 8 cm, homogénea, con áreas de necrosis, originada en el bronquio principal de los lóbulos inferior y medio derechos y que invadió por vecindad en forma de coraza todo el pericardio causando una pericarditis constrictiva tumoral. El estudio microscópico correspondió a un carcinoma broncogénico tipo epidermoide bien diferenciado. El carcinoma broncogénico se asocia frecuentemente con el consumo de cigarrillo

  9. Re-irradiation in stereotactic conditions and cetuximab for local relapses of epidermoid carcinoma of head and neck; Reirradiation en conditions stereotaxiques et cetuximab pour des recidives locales de carcinome epidermoide de la tete et du cou

    Vasseur, F.; Comet, B.; Faivre-Pierret, M.; Coche-Dequeant, B.; Degardin, M.; Lefebvre, J.L.; Lacornerie, T.; Lartigau, E. [Departement universitaire de radiotherapie, centre Oscar Lambret, 59 - Lille (France); Universite Lille-2, 59 (France)

    2010-10-15

    The authors report a work aimed at assessing the feasibility and toxicity of a re-irradiation treatment in stereotactic conditions using CyberKnife and cetuximab in the case of local relapses of epidermoid cancers of the ORL sphere. Thirty three patients have been submitted to this treatment between June 2007 and April 2009. Although six patients died by six months, this treatment seems to be a good alternative, and presents an acceptable short-term toxicity. Further studies are needed to compare this technique to other therapeutic techniques, and to assess the risk of long term complications. Short communication

  10. Epidermoid cyst at a rare location, as a content of inguinal hernia: A case report with a review of the literature

    Meher, Sadananda; Baijal, Manish; Soni, Vandana; Sharma, Anil; Khullar, Rajesh; Chowbey, Pradeep

    2016-01-01

    Epidermoid cysts can occur in a variety of locations including the face, trunk, neck, extremities, and scalp. No case of epidermoid cyst as content of inguinal hernia has been reported so far; however, cases with dermoid, teratoma, lipoma, lymphangioma and leiomyoma as content of inguinal canal have been reported. A 29-year-old female presented with a lump in the left inguinal region that was clinically diagnosed as left inguinal hernia. The patient was planned for laparoscopic inguinal hernia repair after routine investigation. Intraoperatively, a cystic mass was found to be attached to the left round ligament that was excised completely. Histopathological report was consistent with epidermal inclusion cyst. Inguinal epidermoid cyst mimicking inguinal hernia is a rare entity. If such a cyst is encountered during operation, it should be completely excised. PMID:27279405