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Sample records for quiste epidermoide testicular

  1. Esplenectomía por quiste esplénico epidermoide

    Directory of Open Access Journals (Sweden)

    Samuel Rodrigo Gómez Arenas

    2012-01-01

    Full Text Available Los quistes esplénicos son un padecimiento raro. Se manifiestan de forma poco común en la práctica quirúrgica. Se comunica el caso de una paciente con un quiste esplénico diagnosticado en el Departamento de Cirugía General del Hospital General de Zona núm. 4 del IMSS. La mujer, de 21 años de edad, refirió un cuadro clínico con dolor en el hipocondrio izquierdo, que era causado por un tumor de 7 cm de diámetro, aproximadamente. En la TC, se observó que dicho tumor era un quiste esplénico. Se intentó realizar esplenectomía laparoscópica; sin embargo, debido a las adherencias firmes a la pared abdominal y al colon, el procedimiento se llevó a cielo abierto y se hizo esplenectomía total. El estudio histopatológico corroboró el diagnóstico de quiste esplénico epidermoide.

  2. Quiste epidermoide del ciego / Epidermoid cyst of the cecum

    Scientific Electronic Library Online (English)

    Wataru, Yamanaka; Fernando, Llamosas B; Hugo, Adorno R.

    2012-02-01

    Full Text Available Quiste epidermoide es un saco con características benignas que se origina del ectodermo embrionario. Histológicamente consiste en una delgada capa de epitelio escamoso. Quistes epidermoide de ciego son excepcionalmente raros. Reportamos un caso de quiste epidermoide en pared anterior del ciego en un [...] a paciente sin cirugía previa y realizamos una revisión de lo publicado sobre esta patología. Abstract in english Epidermoid cyst is a sac with benign characteristic that originates from embrionary ectoderm. Histologically consists in a thin layer of squamous epithelium. Epidermoid cyst of the cecum are exceptionally rare. We report a case of an epidermoid cyst arising in the anterior wall of the cecum, in a wo [...] man with no previous history of surgery, and review of the literature are presented.

  3. Testicular epidermoid cyst

    Directory of Open Access Journals (Sweden)

    Basri Çakiroglu

    2015-01-01

    Full Text Available Epidermoid cyst of the testis is a benign, non-teratomatous tumour. It is often possible to make the diagnosis pre-operatively, combining typical sonographic features with normal biochemical tumour markers. The accurate pre-operative diagnosis will allow for testis-sparing surgery and prevent unnecessary orchiectomy. An 11-year-old boy with testicular epidermoid cyst who presented with pain in testis was presented in this report.

  4. Concomitant bilateral testicular epidermoid cysts

    International Nuclear Information System (INIS)

    Epidermoid cyst of the testis is a rare benign germ tumor, comprising 1-2% of all resected benign testicular masses. Approximately 300 cases have been reported to date. Unilateral involvement has often been reported in the English literature. However, bilateral occurrence is very rare and to the best of our knowledge, there only 3 previous reports of bilateral testicular epidermoid cysts. The fact that they are completely benign makes them amenable to treatment by local excision, thereby saving patient from orchidectomy. Recognition of their characteristic ulatrsonographic features is very important to avoid unnecessary intervention. We present here, a case of bilateral epidermoid cyst in which characteristic ultrasound (US) findings allowed testis-sparing enucleation instead of radical orchiectomy. (author)

  5. Testis-sparing surgery in testicular mass: Testicular epidermoid cysts

    OpenAIRE

    Mahdavi-Zafarghandi, Reza; Shakiba, Behnam; Ameli, Mojtaba

    2014-01-01

    We present 3 patients with testicular epidermoid cysts who experienced testis-sparing surgery. These patients had a palpable painless testicular mass and underwent inguinal testicular exploration. Intraoperative frozen section revealed no evidence of malignancy and therefore enucleation of the tumour was performed. We demonstrate that careful intraoperative frozen-section examination helps to avoid unnecessary orchidectomy in testicular epidermoid cysts.

  6. Clitoromegalia: quiste epidermoide de clítoris / Clitoromegaly: epidermal cyst of clitoris

    Scientific Electronic Library Online (English)

    Carlos, Ramírez-Isarraraz; Abner, Santos-López; Jaime, Cevallos-Bustillos; Vicente, Miranda-Sevilla.

    2013-12-01

    Full Text Available Objetivo: Describir un caso de clitoromegalia en una mujer perimenopáusica. Lugar: Centro de Tercer Nivel de Atención. Intervenciones: Resonancia magnética, ultrasonido pélvico, marcadores tumorales, clitoroplastia con resección quirúrgica de quiste epidermoide. Resultados: Clitoroplastia más resecc [...] ión de tumor epidermoide con preservación de la anatomía y sensibilidad. Conclusión: Paciente femenina de 52 años, sin antecedentes de trauma pélvico, quien desarrolló un caso inusual de clitoromegalia sin dolor u otros síntomas, además de un notorio crecimiento tumoral en los últimos cuatro años en el cual la malignidad fue descartada. Hay pocos casos de quistes epidermoides en ausencia de trauma o mutilación de genitales reportados en la literatura; generalmente son solitarios, de crecimiento lento y asintomáticos, localizados usualmente en la piel, el cuello o el tronco del clítoris. El procedimiento realizado fue una clitoroplastia con resección del quiste epidermoide, en el cual se ha preservado tanto la anatomía como la sensibilidad sin complicaciones después de seis meses de seguimiento. Abstract in english Objective: Describe a case of clitoromegaly in a perimenopausal female. Setting: Third Level Attention Center. Interventions: Magnetic resonance imaging, pelvic ultrasound, tumoral markers, clitoroplasty with surgical extirpation of epidermal cyst. Results: Clitoroplasty with surgical extirpation of [...] epidermal cyst and preservation of the anatomy and sensitivity. Conclusions: A 52 years old female patient without history of pelvic trauma who developed an unusual case of clitoromegaly without pain nor any symptoms besides notorius tumor growing over past four years in which malignancy was discarded. There are very few epidermal cyst cases in the absence of trauma or genitalia mutilation reported in literature; they are usually solitary tumors, with slow growing and asymptomatic. Usually localized in clitoral scalp, neck or trunk. The performed procedure was a clitoroplasty with extirpation of an epidermal cyst, where has been well preserved the anatomy and sensitivity, without any complication after six months follow up.

  7. Quiste epidermoide en la región preauricular: Reporte de un caso / Epidermoid cyst into preauricular region: A case report

    Scientific Electronic Library Online (English)

    Oscar, Venegas R; Benjamín, Martínez R; Bárbara, Olivos B; Carolina, Vallejos & #924; ; Mauricio, Zambra R.

    2011-08-01

    Full Text Available Los quistes dermoides son malformaciones que ocurren en el área de cabeza y cuello con una frecuencia de 1,6% a 6,9%. Histológicamente podemos clasificarlos en epidermoide, dermoide o teratoide. Presentamos un caso de un paciente de sexo masculino, quien se presentó en nuestro hospital con un quiste [...] preauricular, que fue enucleado y confirmado histopatológicamente como quiste epidermoide. Abstract in english Dermoid cysts are malformations occurring in the head and neck region with an incidence ranging from 1.6% to 6.9%. Histologically, they can be further classified as epidermoid, dermoid or teratoid. We report a case of adult male who presented at our hospital with a preauricular cyst; it was excised [...] and confirmed histopathologically as an epidermoid cyst.

  8. Quiste epidermoide en la región preauricular: Reporte de un caso Epidermoid cyst into preauricular region: A case report

    Directory of Open Access Journals (Sweden)

    Oscar Venegas R

    2011-08-01

    Full Text Available Los quistes dermoides son malformaciones que ocurren en el área de cabeza y cuello con una frecuencia de 1,6% a 6,9%. Histológicamente podemos clasificarlos en epidermoide, dermoide o teratoide. Presentamos un caso de un paciente de sexo masculino, quien se presentó en nuestro hospital con un quiste preauricular, que fue enucleado y confirmado histopatológicamente como quiste epidermoide.Dermoid cysts are malformations occurring in the head and neck region with an incidence ranging from 1.6% to 6.9%. Histologically, they can be further classified as epidermoid, dermoid or teratoid. We report a case of adult male who presented at our hospital with a preauricular cyst; it was excised and confirmed histopathologically as an epidermoid cyst.

  9. Epidermoid Cysts of Head and Neck Region: Case Series and Review of Literature / Quistes Epidermoides de Región Cabeza y Cuello: Serie de Casos y Revisión de la Literatura

    Scientific Electronic Library Online (English)

    S, Sunil; Neetu, Oommen; R, Rathy; V. R, Rekha; Divya, Raj; V. K, Sruthy.

    2014-09-01

    Full Text Available Los quistes epidermoides y dermoides son hamartomas localizados en el cuello, la cabeza o el tronco, por lo general visibles al nacer. En algunos casos, el examen médico cuidadoso puede ayudar a encontrar quistes epidermoides y dermoides. Existe cierta ambigüedad acerca de su patogenia exacta, postu [...] lando teorías disontogenéticas, traumáticas y anomalías del conducto tirogloso. Los quistes epidermoides histopatológicamente tienen una cápsula quística revestida con epitelio estratificado delgado. Aunque la escisión quirúrgica completa es su tratamiento, se han reportado complicaciones. Presentamos tres casos de quiste epidermoides en la región maxilofacial. Abstract in english Epidermoid and dermoid cysts are hamartomas localized on the neck, head, or trunk, usually visible at birth. In some instances, careful medical examination may help to find most epidermoid and dermoid cysts. Ambiguity about their exact pathogenesis exists and dysontogenetic, traumatic, and thyroglos [...] sal anomaly theories have been postulated. Histopathologically epidermoid cysts have a cystic capsule lined with thin stratified epithelium. Surgical excision though completes the treatment, complications have been reported. We report three cases of epidermoid cyst on the maxillofacial region.

  10. Teratoma quístico maduro testicular (quiste dermoide): Aportación de un caso y revisión de la literatura / Mature cystic teratoma of the testis (dermoid cyst): Case report and literature review

    Scientific Electronic Library Online (English)

    P., Garrido Abad; L.M., Herranz Fernández; M., Jiménez Gálvez; C., Suárez Fonseca; D., Santos Arrontes; S., Nieto Llanos; M., Fernández Arjona.

    2009-11-01

    Full Text Available Objetivos: Aportamos un caso de un teratoma quístico maduro testicular (quiste dermoide) en su variante pseudopilomatrixoma. Métodos: Paciente de 53 años con una masa testicular izquierda no dolorosa al que, tras la realización de orquiectomía radical, se diagnostica de teratoma quístico maduro test [...] icular (quiste dermoide) en su variante pseudopilomatrixoma. Estudio de extensión y marcadores tumorales negativos. El paciente se encuentra libre de enfermedad tras 6 meses de seguimiento. Resultados: El teratoma testicular es un tumor compuesto por células derivadas de las tres hojas embrionarias (ectodermo, endodermo y mesodermo). Aparecen a cualquier edad, siendo mucho más incidentes en la infancia, donde llegan a representar hasta un 30% de todos los tumores. En la edad adulta es mucho menos prevalente, llegando sólo a representar un 7% de todos los tumores germinales del testículo. Conclusiones: Los casos prepuberales son casi invariablemente de carácter benigno, independientemente de su histología. Sin embargo, los casos que aparecen tras la pubertad presentan potencial maligno, incluso si es histológicamente puro. El teratoma quístico maduro (quiste dermoide) representa la única excepción a esta regla, ya que no se ha publicado ninguna degeneración maligna de este tipo de tumores. Abstract in english Objectives: Case report of a mature cystic teratoma (dermoid cyst), pseudopilomatrixoma like variant. Method: 53-year old patient with a left testicular mass, diagnosed as mature cystic teratoma of the testis (dermoid cyst), the pilomatrixoma-like variant, after radical orchiectomy. Tumoral markers [...] were negative and no extension was observed. The patient is disease-free after 6 months follow-up. Results: Testicular teratoma is a tumour composed of cells derived from the three embryonic layers (ectoderm, endoderm and mesoderm). They can appear at any age, but they are much more prevalent in childhood. They appear at any age, but are much more common in childhood, where they comprise up to 30% of all tumours. They are much less prevalent in adults, representing only 7% of all testicular germ cell tumours Conclusions: Prepubertal cases are invariably benign in nature, regardless of their histology. However, cases which appear after puberty are potentially malignant, even if histologically pure. Mature cystic teratoma (dermoid cyst) is the only exception to this rule, as no malignant degeneration of these types of tumours has been published.

  11. Epidermoid cyst of the testis: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Docal, I.; Crespo, C.; Pardo, A.; Prieto, A.; Alonso, P. [Servicio de Radiologia, Hospital Da Costa, Burela (Lugo) (Spain); Calzada, J. [Servicio de Anatomia Patologica, Hospital Da Costa, Burela (Lugo) (Spain)

    2001-05-01

    Epidermoid cyst of the testis is an uncommon benign tumour, with an overall incidence of 1-2 % of all resected testicular masses. When imaging findings suggest that an intratesticular mass is likely to be an epidermoid cyst, conservative management (enucleation with testicular preservation) can be performed rather than orchidectomy. This case report records an epidermoid cyst in a 12-year-old boy in whom the US findings allowed testis-sparing surgery instead of orchidectomy. (orig.)

  12. Benign Intratesticular Epidermoid Cyst of the Testis: Diagnostic Dilemma

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    Kishor H Suryawanshi

    2014-05-01

    Full Text Available Intratesticular epidermoid cysts of the testis are rare benign lesions, comprising about 1-2% of all the testicular neoplasms. Clinically it may not be differentiated reliably from the most common malignant testicular tumours and poses a diagnostic dilemma. Majority of the testicular tumours are malignant one, hence accurate diagnosis in benign lesions such as epidermoid cyst is always warranted to avoid unnecessary invasive procedures like orchidectomy. Herein, we present a case of benign, intratesticular epidermoid cyst of the testis in a 30 years old male treated by conservative approach with testicular preservation, avoiding unnecessary orchidectomy.

  13. Pineal epidermoid

    Science.gov (United States)

    Senapati, Satya B.; Mishra, Sudhansu S.; Patnaik, Ashis; Patra, Sunil K.

    2012-01-01

    Background: Tumors of pineal region are uncommon, accounting for ?1% of intracranial tumors in adults and 3–8% of pediatric brain tumors. Epidermoid cysts account for 0.2–1% of all intracranial tumors. The majority occur in and around the cerebellopontine angle and suprasellar area. Getting an epidermoid in pineal region is very rare. Case Description: We report a case of pineal epidermoid, which was diagnosed correctly as epidermoid depending on computed tomography (CT) and magnetic resonance imaging (MRI) findings. Knowing its benign nature, we accordingly planned for its near-total removal. Conclusion: Most cases of pineal tumors present as obstructive hydrocephalus. They either require pre- or postoperative ventriculoperitoneal (VP) shunt. If properly planned, many benign pineal tumors may be successfully excised and, most importantly, postoperative VP shunt could be avoided. PMID:23226611

  14. Epidermoid cyst post dermofasciectomy.

    LENUS (Irish Health Repository)

    Henry, Francis P

    2010-01-01

    We report the finding of an unusual presentation of an epidermoid cyst 3 years following dermofasciectomy for Dupuytren\\'s disease. Epidermoid cysts remain a rare entity in the palmoplanter distribution but also a very unusual finding within the confines of a full thickness skin graft.

  15. Quistes pulmonares congénitos

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    Nuvia Suárez García

    2014-06-01

    Full Text Available Introducción: las malformaciones pulmonares congénitas constituyen una alteración en el desarrollo embriológico y fetal de las distintas estructuras pulmonares y una rara expresión de estas son los quistes pulmonares congénitos. Caso clínico: se presenta un recién nacido a término, de buen peso, asintomático y estable hasta el tercer día de vida al debutar con un estado de shock séptico secundario, de bronconeumonía complicada con derrame pleural derecho. En los estudios evolutivos hacia el cuarto de día de vida se le diagnostica como hallazgo radiológico la presencia de quistes pulmonares que evolucionan de forma asintomática. Después de una valoración multidisciplinaria es egresado con un seguimiento por su condición de alto riesgo. Actualmente saludable y con buen desarrollo psicomotor. Conclusiones: la importancia del tema que se presenta es que se describe una presentación rara de quistes pulmonares congénitos en un recién nacido que desarrolló un estadio avanzado de sepsis.

  16. Quiste dermoide corneal bilateral

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    Michel Guerra Almaguer

    2015-06-01

    Full Text Available El dermoide es un tipo de coristoma (tejido embrionario normal en una localización anormal que afecta con frecuencia la córnea. Aparece como una masa sólida, blanca, redonda y elevada. Suele localizarse en el limbo inferotemporal, aunque puede hacerlo en cualquier lugar del globo ocular o de la órbita. Se presenta un paciente masculino, de 8 años de edad, quien desde su nacimiento muestra una mancha blanca en ambos ojos, agudeza visual sin corrección de movimiento de mano a 33 centímetros en el ojo derecho y percepción luminosa en el ojo izquierdo. En la exploración oftalmológica de ambos ojos se apreciaron lesiones blanquecinas sobre la córnea. Se le realizó exéresis del quiste y queratoplastia lamelar de ambos ojos, con resultados visuales satisfactorios. Se concluye que el caso presenta un quiste dermoide corneal bilateral.

  17. Quiste dermoide cervical

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    Yurian Gbenou Morgan

    2015-09-01

    Full Text Available Los quistes dermoides presentan una incidencia de 1,6 hasta 6,9 % en la región de cabeza y cuello. Se realiza el siguiente reporte de caso clínico con el objetivo de enfatizar en la importancia de un adecuado manejo diagnóstico preoperatorio, para establecer una acertada planificación quirúrgica en la exéresis de este tipo de lesiones de la región cervicofacial. Se presenta el caso clínico de un paciente masculino, de 13 años de edad, quien hacía 3 años se notaba un crecimiento redondeado en región submentoniana, lo cual le ocasionaba molestias al hablar y ligera afectación de su estética facial. Una vez realizados los estudios complementarios preoperatorios, se decide tratamiento quirúrgico, empleando una cervicotomía medial para la extirpación de la lesión quística, dada la ubicación anatómica por debajo del músculo milohiodeo y su gran dimensión. El diagnóstico histopatológico se corresponde con un quiste epidérmico. Se concluye que resulta imprescindible realizar un exhaustivo examen físico e imagenológico, para lograr resultados satisfactorios en el tratamiento quirúrgico del quiste dermoide cervical.

  18. MASA NASAL CONGÉNITA: QUISTE EPIDERMOIDE Congenital nasal mass: epidermoid and dermoid cyst

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    Gilberto Eduardo Marrugo-Pardo

    2010-12-01

    Full Text Available Las masas nasales congénitas de la línea media son poco frecuentes, pero ante la sospecha clínica debe realizarse una valoración completa que incluya imágenes diagnósticas para descartar origen intracraneal. Se presenta un caso clínico con la presencia de dos entidades clínicas de diferentes características histológicas junto con una revisión de la literaturaCongenital midline nasal mass are infrequent but before the clinical suspicion should be carried out a complete evaluation that includes diagnostic images with the aim of ruled out intracraneal lesion. This paper presented a clinical case is with two clinical entities of different histological characteristic together with a revision of the literature.

  19. Intracranial epidermoid carcinoma: CT and MRI

    Energy Technology Data Exchange (ETDEWEB)

    Uchino, A. [Kyushu Univ. Hospital, Fukuoka (Japan). Dept. of Radiology; Hasuo, K. [Kyushu Univ. Hospital, Fukuoka (Japan). Dept. of Radiology; Matsumoto, S. [Kyushu Univ. Hospital, Fukuoka (Japan). Dept. of Radiology; Uda, K. [Kyushu Univ. Hospital, Fukuoka (Japan). Dept. of Neurosurgery; Moriguchi, M. [Kyushu Univ. Hospital, Fukuoka (Japan). Dept. of Neurosurgery; Nishio, T. [Kyushu Univ. Hospital, Fukuoka (Japan). Dept. of Neurosurgery; Fukui, M. [Kyushu Univ. Hospital, Fukuoka (Japan). Dept. of Neurosurgery; Masuda, K. [Kyushu Univ. Hospital, Fukuoka (Japan). Dept. of Radiology

    1995-02-01

    We report a patient with an epidermoid carcinoma an extremely rare brain tumour, in the right cerebellopontine angle cistern. Contrast enhancement is the most important feature for differential diagnosis of epidermoid carcinomas from atypical benign epidermoid cysts. (orig.)

  20. Neuroradiological aspects of intracranial epidermoids

    International Nuclear Information System (INIS)

    Intracranial epidermoids are primarily extracerebral congenital cysts. Intra- and extradural types are differentiated: intradural lesions originate in the intracranial CSF spaces, and extradural lesions in the bony skull. Epidermoids increase in size passively as the results of an increase in the cyst volume and not because of active growth. Clinically epidermoids behave like benign, slow-growing cerebral tumours. Differential diagnosis includes other cysts and cystic tumours. Neuroradiologically epidermoids present as polycystic lesions showing extensive growth in the extracerebral CSF spaces and secondary invagination of the brain. On CT and MR, despite the high cholesterol content, epidermoids show the characteristics of liquor and not those of fat. It can be shown that he typical CT and MR appearance of an epidermoid is due to the different proportions of CSF in the cyst content, which results from diffusion of dehiscence of te cyst capsule. The present study was based on analysis of 6 cases selected from a total of 29 patients with CNS epidermoids. (orig.)

  1. Testicular Exams

    Science.gov (United States)

    ... Can I Help a Friend Who Cuts? Testicular Exams KidsHealth > For Teens > Testicular Exams Print A A ... in the habit of regular testicular exams. The Exam Your doctor should examine your testicles at least ...

  2. Quiste coloide del tercer ventrículo

    Scientific Electronic Library Online (English)

    Juan, Dávila Meneses.

    2012-09-01

    Full Text Available Los quistes coloides son lesiones intracraneales con una incidencia calculada en tres individuos por millón de personas en un año. Son tumores benignos de la porción anterosuperior del tercer ventrículo. El flujo normal del líquido cefalorraquídeo puede ser interrumpido por un gran quiste que obstru [...] ya el foramen de Monro. Los signos y síntomas asociados engloban un espectro amplio de características, desde una cefalea no específica hasta datos de hipertensión intracraneal; algunos quistes coloides se dan en el comienzo agudo de una hidrocefalia y pueden llevar a una muerte súbita. Caso: presentamos el caso de un adolescente masculino de 13 años de edad, de raza negra, quien dos días antes de su fallecimiento había manifestado cefalea. Al examen de autopsia se evidenció un quiste coloide del tercer ventrículo que produjo una hidrocefalia aguda obstructiva, con edema cerebral severo y herniación de amígdalas cerebelosas. En este artículo comentamos las características principales del quiste coloide y realizamos una breve revisión bibliográfica Abstract in english Colloid cysts are intracranial lesions with an estimated incidence of three individuals per million people per year. They are benign tumors of the anterior portion of the third ventricle. The normal flow of cerebrospinal fluid may be interrupted by a large cyst obstructing the foramen of Monro. The [...] signs and symptoms associated cover a wide range of features, from a non-specific headaches to intracranial hypertension data, some colloid cysts occur in the acute onset of hydrocephalus and can lead to sudden death. Case: We present the case of an adolescent male 13 years of age, black race, who two days before his death had expressed headache. On examination autopsy showed a third ventricular colloid cyst that caused acute obstructive hydrocephalus with severe cerebral edema and herniation of cerebellar tonsils. In this article we discuss the main features of the colloid cyst and performed a brief literature review

  3. Quiste coloide del tercer ventrículo

    Directory of Open Access Journals (Sweden)

    Juan Dávila Meneses

    2012-09-01

    Full Text Available Los quistes coloides son lesiones intracraneales con una incidencia calculada en tres individuos por millón de personas en un año. Son tumores benignos de la porción anterosuperior del tercer ventrículo. El flujo normal del líquido cefalorraquídeo puede ser interrumpido por un gran quiste que obstruya el foramen de Monro. Los signos y síntomas asociados engloban un espectro amplio de características, desde una cefalea no específica hasta datos de hipertensión intracraneal; algunos quistes coloides se dan en el comienzo agudo de una hidrocefalia y pueden llevar a una muerte súbita. Caso: presentamos el caso de un adolescente masculino de 13 años de edad, de raza negra, quien dos días antes de su fallecimiento había manifestado cefalea. Al examen de autopsia se evidenció un quiste coloide del tercer ventrículo que produjo una hidrocefalia aguda obstructiva, con edema cerebral severo y herniación de amígdalas cerebelosas. En este artículo comentamos las características principales del quiste coloide y realizamos una breve revisión bibliográficaColloid cysts are intracranial lesions with an estimated incidence of three individuals per million people per year. They are benign tumors of the anterior portion of the third ventricle. The normal flow of cerebrospinal fluid may be interrupted by a large cyst obstructing the foramen of Monro. The signs and symptoms associated cover a wide range of features, from a non-specific headaches to intracranial hypertension data, some colloid cysts occur in the acute onset of hydrocephalus and can lead to sudden death. Case: We present the case of an adolescent male 13 years of age, black race, who two days before his death had expressed headache. On examination autopsy showed a third ventricular colloid cyst that caused acute obstructive hydrocephalus with severe cerebral edema and herniation of cerebellar tonsils. In this article we discuss the main features of the colloid cyst and performed a brief literature review

  4. Quiste residual gigante: presentación de un caso

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    Oscar Rivero Pérez

    2014-01-01

    Full Text Available Fundamento: u n quiste es una estructu ra con tendencia a la forma redondeada, constituida por una pared externa de tejido conectivo fibroso, una pared interna formada por un tapiz epitelial. La cavidad quística contiene un material líquido o semilíquido de color cetrino que, cuando se infecta, se convierte en purulento y carmelitoso. El quiste residual puede haber sido anteriormente un quiste lateral o un quiste apical y al haberse extraído el diente, a par tir de cuyo periodonto se forma el quiste , se queda en el tejido óseo sin haber sido exti rpado. Objetivo: presentar un caso al cual se le diagnosticó y trató un quiste residual mandibular que abarcaba la hemiarcada izquierda, que permitió restablecer las funciones masticatorias y estética. Caso Clínico: paciente que fue atendido en la consult a de Cirugía Maxilofacial de la Facultad de Estomatología de Camagüey , con un aumento de volumen en la región lateral izquierda, con antecedentes de trauma anterior que le provocó fractura de mandíbula. Se describen las características clínicas de la enfer medad y el tratamiento quirúrgico realizado, se utilizó para el mismo los principios de la técnica de enucleación . 577 Conclusiones: a unque se han reportados pocos c asos en la l iteratura nacional y extranjera, estos han sido quiste s de menor tamaño que inclu yen uno o dos dientes, no existen reportes de quistes residuales que involucren toda la arcada o hemiarcada dentaria. Se obtuvieron resultados estéticos satisfactorios con la técnica quirúrgica empleada y no se presentaron complicaciones.

  5. Quiste dermoide del suelo de la boca

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    Ayelén María Portelles Massó

    2010-12-01

    Full Text Available El quiste dermoide representa menos del 0,01 % de todos los quistes de la cavidad bucal. Su ubicación más frecuente es en suelo de boca. Se presenta el caso de una paciente femenina de 19 años de edad que hacía aproximadamente 7 años había notado un aumento de volumen debajo de la lengua, el cual le crecía paulatinamente y ya se apreciaba por fuera de la cara. Además, le ocasionaba molestias al hablar y al masticar. Se realizaron estudios complementarios y bajo anestesia general nasotraqueal. Se procedió a su exéresis quirúrgica mediante un abordaje intrabucal, donde se obtuvieron excelentes resultados estéticos y funcionales. El diagnóstico histopatológico se correspondió con un quiste dermoide de suelo de boca. La paciente no ha tenido recurrencia de la lesión transcurridos tres años de la operación. El quiste dermoide de suelo de boca se presenta como una tumoración benigna de la línea media. La exéresis intrabucal demuestra beneficios estéticos y funcionales.

  6. Quiste de colédoco tipo IV A

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    Lucas Esteban Granero

    2009-01-01

    Full Text Available El quiste de colédoco tipo IV A es una enfermedad muy poco común caracterizada por una dilatación quística congénita del árbol biliar que se extiende también a los canalículos biliares intrahepáticos. Se comunica el caso de una mujer de 19 años de edad con ictericia y dolor abdominal. La paciente fue sometida a una amplia evaluación clínica, analítica y por imágenes. La tomografía computada y la colangiopancreatografía por resonancia magnética revelaron un quiste coledociano de 13.5 cm con compromiso intrahepático. Se combinó la resección de la parte extrahepática del quiste con una hepaticoyeyunoanastomosis en Y de Roux. Se descubrió una estructura ductal en la parte distal del quiste extrahepático. No hubo complicaciones perioperatorias ni alejadas en el seguimiento.

  7. Epidermoid Cyst of the Cecum

    Science.gov (United States)

    Park, Jae-Young; Kim, Youn Wha; Lee, Kil Yeon

    2015-01-01

    An epidermoid cyst of the cecum is extremely rare; only eight cases have been reported in the literature. A 63-year-old woman was admitted to Kyung Hee University Medical Center with a colonic mass that had been discovered incidentally during a regular health check-up. The radiographic impression was that this mass was a gastrointestinal stromal tumor. During surgery, an exophytic mass in the cecal wall was resected by using an ileocecectomy. Based on the macroscopic and the microscopic findings, this case was identified as an epidermoid cyst of the cecal wall. We report this case to discuss the origin of this entity and the unusual nature of our case. PMID:25745626

  8. Recidiva tardía de carcinoma epidermoide de pene / Epidermoid pennis carcinoma recidive

    Scientific Electronic Library Online (English)

    E., Sanz Mayayo; R., Rodríguez-Patrón Rodríguez; I., Gómez García; D., García Ortells; R., García Navas; R., García González; Á., Escudero Barrilero.

    2003-12-01

    Full Text Available OBJETIVO: Presentar un caso de recidiva de carcinoma epidermoide de pene a los 21 años de la cirugía. MÉTODO: Se trata de un paciente de 85 años con antecedentes de penectomía parcial por carcinoma epidermoide, que presenta lesión excrecente a nivel de glande de 1 mes de evolución. Se biopsia siendo [...] el resultado carcinoma epidermoide por lo que se realiza penectomía total con uretrostomía cutánea. RESULTADO: El estudio histopatológico de la pieza confirmó un carcinoma epidermoide bien diferenciado. Abstract in english OBJETIVE: We report a recidive of pennis carcinoma after 21 years of surgery. METHODS: This is the case of a male of 85 years old, with parcial penectomy; by epidermoid carcinoma. In phisics exploration, that it displays excrecente lesion at level of glande of 1 month of evolution. Biopsy being the [...] result of epidermoid carcinoma reason why is made. Total penectomy, a with cutaneus uretrostomy. RESULTS: The histopathological study of the piece, confirm a epidermoid carcinoma well differentiated.

  9. Quiste suprarrenal primario / Primary adrenal cyst

    Scientific Electronic Library Online (English)

    Patricio, Cabané T; Patricio, Gac M; Jorge, Mariño B; Daniela, Ibacache A; Alejandra, Ledezma S; Claudia, Morales H.

    2011-12-01

    Full Text Available Los quistes suprarrenales son las lesiones quísticas más frecuentes de la glándula suprarrenal, a pesar de que constituyen una rara entidad. Típicamente se presentan por un cuadro de dolor abdominal o masa palpable, pero en la actualidad se detectan cada vez con más frecuencia en estudios radiológic [...] os como incidentalomas. Los quistes suprarrenales cuentan con amplios diagnósticos diferenciales, lo que hace un difícil diagnóstico definitivo y una dificultad en el manejo posterior. Estos quistes se clasifican en cuatro subtipos: endoteliales, pseudoquiste, epiteliales y parasitarios. El manejo de un quiste suprarrenal se puede resumir en tres pilares fundamentales: descartar el estado funcional del quiste, evaluación de eventual malignidad por imágenes, y evitar las posibles complicaciones (hemorragia, infección), sobre todo en los quistes de gran tamaño. Se presenta el caso de una paciente con quiste suprarrenal izquierdo no funcionante asociado a dolor abdominal. Se realiza revisión de la literatura y se plantean los distintos diagnósticos y alternativas terapéuticas. Abstract in english Adrenal cyst is the commonest type of benign lesions of adrenal gland, althought is a very rare entity. Tipically, they are presented with abdominal pain or palpable mass, but nowdays they are detected most frecuently an imaging studies like incidentaloma. Adrenal Cyst have a broad differential diag [...] noses, rendering definitive diagnosis and subsequent management difficult. Are categorized into four subtypes: endothelial, pseudocyst, epithelial, and parasitic. This management paradigm may be summarized as: ruling out functional status of the cyst, evaluating chances of incidental malignancy by imaging, avoiding potential complications of surveillance (hemorrhage, infection), particularly in large cysts. A case of a patient with a left non-functioning adrenal cyst is reported, with abdominal pain. The diagnostic and therapeutic options are discussed and the literature is reviewed.

  10. Quiste suprarrenal primario Primary adrenal cyst

    Directory of Open Access Journals (Sweden)

    Patricio Cabané T

    2011-12-01

    Full Text Available Los quistes suprarrenales son las lesiones quísticas más frecuentes de la glándula suprarrenal, a pesar de que constituyen una rara entidad. Típicamente se presentan por un cuadro de dolor abdominal o masa palpable, pero en la actualidad se detectan cada vez con más frecuencia en estudios radiológicos como incidentalomas. Los quistes suprarrenales cuentan con amplios diagnósticos diferenciales, lo que hace un difícil diagnóstico definitivo y una dificultad en el manejo posterior. Estos quistes se clasifican en cuatro subtipos: endoteliales, pseudoquiste, epiteliales y parasitarios. El manejo de un quiste suprarrenal se puede resumir en tres pilares fundamentales: descartar el estado funcional del quiste, evaluación de eventual malignidad por imágenes, y evitar las posibles complicaciones (hemorragia, infección, sobre todo en los quistes de gran tamaño. Se presenta el caso de una paciente con quiste suprarrenal izquierdo no funcionante asociado a dolor abdominal. Se realiza revisión de la literatura y se plantean los distintos diagnósticos y alternativas terapéuticas.Adrenal cyst is the commonest type of benign lesions of adrenal gland, althought is a very rare entity. Tipically, they are presented with abdominal pain or palpable mass, but nowdays they are detected most frecuently an imaging studies like incidentaloma. Adrenal Cyst have a broad differential diagnoses, rendering definitive diagnosis and subsequent management difficult. Are categorized into four subtypes: endothelial, pseudocyst, epithelial, and parasitic. This management paradigm may be summarized as: ruling out functional status of the cyst, evaluating chances of incidental malignancy by imaging, avoiding potential complications of surveillance (hemorrhage, infection, particularly in large cysts. A case of a patient with a left non-functioning adrenal cyst is reported, with abdominal pain. The diagnostic and therapeutic options are discussed and the literature is reviewed.

  11. Dev sublingual epidermoid kist: Olgu sunumu

    OpenAIRE

    Yüce, Salim; Polat, Kerem; Uysal, ?smail Önder; Bekar, Abuzer; Müderris, Suphi

    2013-01-01

    Epidermoid and dermoid cysts are benign lesions, that can be seen in different parts of the body. They are seen in oral cavity about 1.6% and are very rare in oral cavity cysts. We presented our case with a giant sublingual epidermoid cyst, a rarely seen pathology with a literature review.

  12. Carcinoma papilar de tiroides en quiste tirogloso

    Scientific Electronic Library Online (English)

    JULIÁN ANDRÉS, MOLANO G; GONZALO, ROSSEL DE LA M; MIGUEL, GONZÁLEZ P; INGRID, PLASS DEL C.

    2013-06-01

    Full Text Available Objetivo: Reportar un caso raro de carcinoma papilar en un quiste tirogloso y discutir su manejo. Paciente y Método: Un hombre de 72 años a quien se realizó un diagnóstico clínico de un quiste tirogloso, fue llevado a una cirugía de Sistrunk's y luego una tiroidectomía total ante la evidencia de cán [...] cer papilar en el quiste tirogloso. Resultados: El examen histopatológico reveló un carcinoma papilar de tiroides en el quiste tirogloso y la glándula tiroides fue normal, el paciente permaneció libre de enfermedad en su seguimiento. Conclusiones: La mayoría de los cánceres que surgen en quiste del conducto tirogloso son de bajo riesgo, y el procedimiento Sistrunk's con una tiroidectomía total es un tratamiento adecuado para este tipo de cáncer. Abstract in english Papillary carcinoma in thyroglossal duct cyst Background: To report a rare case of papillary carcinoma in thyroglossal duct cyst and discuss its management. Material and Method: A 72 year-old man was clinically diagnosed to have a big thyroglossal duct cyst. Sistrunk's procedure followed by total th [...] yroidectomy on the evidence of papillary cancer in thyroglossal duct cyst. Results: Histopathologic examination revealed a papillary carcinoma in the thyroglossal duct cyst and normallity in the thyroid gland. The patient remained free of disease on follow-up. Conclusion: Most cancers arising in thyroglossal duct cyst are of low risk, and Sistrunk's procedure with a total thyroidectomy is an adequate treatment for such cancers.

  13. Quiste odontógeno: Presentación de caso

    Directory of Open Access Journals (Sweden)

    Gladys Pérez López

    2003-12-01

    Full Text Available Se presenta un paciente de 18 años de edad, remitido al Servicio de Otorrinolaringología del Hospital Clinicoquirúrgico "Comandante Manuel Fajardo", con el cuadro clínico de sinusitis recurrente y opacidad homogénea de seno maxilar izquierdo . La radiografia convencional de senos perinasales es considerada un medio diagnóstico muy importante al nivel de la atención primaria de salud, aunque también se considera necesario el ortopantograma para el diagnóstico diferencial (dientes supernumerarios, quistes dentígenos, molares retenidos. La técnica de Caldwell-Luc mejora la visibilidad y accesibilidad de las lesions, contribuye al diagnóstico, al alivio del paciente y está exenta de complicaciones.A case of 18-years old male patient with recurrent maxillary sinusitis and radiographic study with opacity in left maxillay sinus was reported. He was admitted at the Otorhinolaringology Department of "Comandante Manuel Fajardo" university clinical and surgical hospital. Conventional radiographic examination of perinasal sinus is considered a very important tool in primary health care; but also orthopantogram is required to exclude diverse diagnosis (supernumerary teeth, dentigenous cyst, and embedded tooth. The Caldwell-Luc approach improves visibility of and accesibility to lesions, contributes to make diagnosis and relieves the patient's condition without further complications. The most relevant quotations found in research works about the topic were selected.

  14. Testicular Injuries

    Science.gov (United States)

    ... are protected. When you're exercising or playing sports, make sure that using protective gear is part of your routine and you'll be able to play hard without fear of testicular injury! Reviewed by: T. Ernesto Figueroa, ...

  15. Testicular self-exam

    Science.gov (United States)

    Screening - testicular cancer - self-exam; Testicular cancer - screening - self-exam ... A testicular self-exam is done to check for testicular cancer . Testicles have blood vessels and other structures that can make the exam ...

  16. Neuroradiological aspects of intracranial epidermoids; Zur neuroradiologischen Diagnostik der intrakraniellen Epidermoide

    Energy Technology Data Exchange (ETDEWEB)

    Hagen, T. [Universitaetskliniken des Saarlandes, Homburg/Saar (Germany). Inst. fuer Neuroradiologie; Kujat, C. [Universitaetskliniken des Saarlandes, Homburg/Saar (Germany). Inst. fuer Neuroradiologie; Donauer, E. [Universitaet des Saarlandes, Homburg/Saar (Germany). Neurochirurgische Klinik; Piepgras, U. [Universitaetskliniken des Saarlandes, Homburg/Saar (Germany). Inst. fuer Neuroradiologie

    1994-11-01

    Intracranial epidermoids are primarily extracerebral congenital cysts. Intra- and extradural types are differentiated: intradural lesions originate in the intracranial CSF spaces, and extradural lesions in the bony skull. Epidermoids increase in size passively as the results of an increase in the cyst volume and not because of active growth. Clinically epidermoids behave like benign, slow-growing cerebral tumours. Differential diagnosis includes other cysts and cystic tumours. Neuroradiologically epidermoids present as polycystic lesions showing extensive growth in the extracerebral CSF spaces and secondary invagination of the brain. On CT and MR, despite the high cholesterol content, epidermoids show the characteristics of liquor and not those of fat. It can be shown that he typical CT and MR appearance of an epidermoid is due to the different proportions of CSF in the cyst content, which results from diffusion of dehiscence of te cyst capsule. The present study was based on analysis of 6 cases selected from a total of 29 patients with CNS epidermoids. (orig.) [Deutsch] Intrakranielle Epidermoide sind primaer extrazerebrale kongenitale Zysten. Es sind intra- von extraduralen Formen zu unterscheiden. Intradurale Epidermoide entstehen in den intrakraniellen Liquorraeumen, extradurale im Schaedelknochen. Epidermoide vergroessern sich nicht aktiv durch autonomes Wachstum, sondern passiv durch Zunahme des Zysteninhalts. Klinisch verhalten sie sich wie gutartige, langsam wachsende Hirntumoren. Differential-diagnostisch sind sie gegenueber anderen Zysten und zystischen Tumoren abzugrenzen. Neuroradiologisch sind Epidermoide durch ihre polyzyklische Konfiguration und ihre extensive Ausdehnung in den extrazerebralen Liquorraeumen mit sekundaerer Invagination in das Gehirn gekennzeichnet. Im MR und im CT stellen sich Epidermoidzysten trotz des hohen Gehaltes an Cholesterin nicht fett-, sondern liquoraequivalent dar. Es kann nachgewiesen werden, dass die Ursache fuer die Abbildungseigenschaften der Epidermoide in einer unterschiedlichen transmuralen Beimengung von Liquor cerebrospinalis zum Zysteninhalt liegt. Die Studie basiert auf der Analyse von 6 Faellen, die aus einem Gesamtkollektiv von 29 Patienten mit Epidermoiden des Zentralnervensystems ausgewaehlt wurden. (orig.)

  17. Recurrent intramedullary epidermoid cyst of conus medullaris.

    LENUS (Irish Health Repository)

    Fleming, Christina

    2011-01-01

    Spinal intramedullary epidermoid cyst is a rare condition. Recurrent epidermoid cyst in the spine cord is known to occur. The authors describe a case of recurrent conus medullaris epidermoid cyst in a 24-year-old female. She initially presented at 7 years of age with bladder disturbance in the form of diurnal enuresis and recurrent urinary tract infection. MRI lumbar spine revealed a 4 cm conus medullaris epidermoid cyst. Since the initial presentation, the cyst had recurred seven times in the same location and she underwent surgical intervention in the form of exploration and debulking. This benign condition, owing to its anatomical location, has posed a surgical and overall management challenge. This occurrence is better managed in a tertiary-care centre requiring multi-disciplinary treatment approach.

  18. Quiste dermoide verdadero en piso de boca

    Directory of Open Access Journals (Sweden)

    Daniel Antunes Freitas

    2013-09-01

    Full Text Available Los quistes dermoides son lesiones benignas de origen embrionario, con una incidencia del 0,01 % de todos los quistes de la cavidad bucal. No presenta predicción por sexo y alrededor del 60 % de los casos se desarrollan entre los 15 y 35 años de edad. El conocimiento de los hallazgos clínicos de este tipo lesiones es vital para un diagnóstico definitivo, sin embargo, este siempre debe ser corroborado mediante exámenes histopatológicos, especialmente, al realizar un diagnóstico diferencial entre los diferentes tipos de quiste dermoides u otras alteraciones a nivel oral con manifestaciones clínicas similares. El propósito de esta presentación reportar un caso clínico para ampliar conocimientos sobre el diagnóstico y tratamiento de este tipo de lesión debido a su infrecuencia en cavidad oral. La ubicación inusual de estos quistes en cavidad oral hace que, aún con una buena valoración clínica e imaginológica, el diagnóstico prequirúrgico preciso sea difícil. Es por esto que el tratamiento quirúrgico no sólo evita el riesgo de una complicación infecciosa y eventual malignización sino que permite obtener un diagnóstico definitivo mediante estudios histopatológicos.

  19. QUISTE MESENTERICO COMO CAUSA DE ABDOMEN AGUDO

    Scientific Electronic Library Online (English)

    Ana María, Caballero Arévalo; Roberto Carlos, Ríos García; David Carlos, Ramírez López.

    Full Text Available Los quistes mesentéricos son tumores abdominales de asiento en el intestino delgado se originan de los leiomiomas yeyunales que en su evolución desarrollan un quiste mesenterio gigante, o puede ser un tumor primario originado en las hojas mesentéricas constituyen una patología poco frecuente en el a [...] dulto, la causa es un defecto en el desarrollo de los linfáticos mesentéricos, existiendo espacios cerrados en los que se acumula contenido linfático. Los quistes mesentéricos son tumores abdominales benignos poco frecuentes de etiología aún no determinada ocurren en cualquier edad, son causa de abdomen agudo, obstrucción intestinal y el 3% se puede malignizarse. Presentamos el caso de un paciente de sexo masculino de 72 años con abdomen agudo secundario a quiste mesenterio. Abstract in english The Mesenteric cysts are abdominal tumors that develop in thin intestine, they origin from yayunal leiomiomas that in their evolution develop a giant mesenteric cyst, or it can be a primary tumor originated in the mesenteric leafs. They constitute a not very frequent pathology in adults the cause is [...] a defect in the development of mesenteric lymphatics, existing closed spaces in which accumulates lymphatic content. The mesenteric cysts are not very frequent benign abdominal of uncertain etiologv, they appear at any age. they are cause of abdomen pain, intestinal obstruction and 3 % of them can become malignant. We present the case of a masculine sex patient of 72 years old with secondary abdomen pain to cyst mesenteric.

  20. Testicular Cancer

    Science.gov (United States)

    ... of skin behind the penis. You can get cancer in one or both testicles. Testicular cancer mainly affects young men between the ages of ... undescended testicle Have a family history of the cancer Symptoms include pain, swelling, or lumps in your ...

  1. Testicular torsion

    DEFF Research Database (Denmark)

    Brasso, K; Andersen, L; Kay, L; Wille-Jørgensen, P; Linnet, L; Egense, J

    1993-01-01

    Thirty-five patients were examined 6-11 years after operation for torsion of the testis. Loss of testicular tissue was significantly associated with long preoperative duration of symptoms and with low postoperative sperm counts. The sex hormones were normal in the majority of patients but there...

  2. Testicular lymphoma

    DEFF Research Database (Denmark)

    Møller, Michael Boe; d'Amore, F; Christensen, Bjarne Egelund

    In a Danish population-based non-Hodgkin's lymphoma registry, 2687 newly diagnosed patients were registered from 1983 to 1992. 39 had testicular involvement (TL) (incidence 0.26/10(5)/year). Median age was 71 years. 24 cases had localised and 15 had disseminated disease. Histologically, all cases...

  3. Estudio de la fertilidad y viabilidad de quistes hidatídicos ovinos

    Directory of Open Access Journals (Sweden)

    García Llamazares José Luis

    1997-01-01

    Full Text Available FUNDAMENTO: La finalidad de este trabajo es analizar la fertilidad de los quistes hidatídicos de origen ovino, especie de gran interés epidemiológico en la hidatidosis, y la adecuación del gerbillo (Meriones unguiculatus como modelo experimental para el estudio "in vivo" de dicha hidatidosis, fase preliminar de posteriores estudios terapeúticos. MÉTODOS: Se ha realizado un estudio de la fertilidad y viabilidad de quistes hidatídicos procedentes de pulmones e hígados de ganado ovino de Castilla y León a través del examen y evaluación de una serie de parámetros entre los que figura la producción de una hidatidosis secundaria experimental en animales de laboratorio. RESULTADOS: El índice quístico total obtenido fue de 8,57 quistes por ovino infestado (5,97 quistes por pulmón infestado y 5,57 quistes por hígado infestado. El porcentaje de fertilidad obtenido en los quistes hidatídicos de origen ovino que contenían protoescólex viables "in vitro" fue del 43,97% (43,02% en los quistes pulmonares y 46,16% en los quistes hepáticos. La viabilidad "in vivo" de los protoescólex seleccionados se puso de manifiesto al producirse en el 100% de los gerbillos infectados una hidatidosis secundaria experimental. CONCLUSIONES: Se destaca la validez de los criterios utilizados para estudiar la viabilidad "in vitro" de los protoescólex procedentes de quistes hidatídicos de origen ovino. La hidatidosis secundaria producida en gerbillos nos conduce a considerarlos como especie de experimentación adecuada para la investigación "in vivo" de la hidatidosis de origen ovino.

  4. Quiste broncogénico infantil Infantile bronchogenic cyst

    Directory of Open Access Journals (Sweden)

    Jorge Neira M

    2004-11-01

    Full Text Available El quiste broncogénico es una anomalía congénita benigna del sistema embrionario y rara vez se diagnostica en el periodo de recién nacido. Se presenta el caso de un lactante de 10 meses hospitalizado por bronquiolitis moderada con tos, dificultad respiratoria, fiebre y vómitos causada por virus Influenza A. La radiografía de tórax mostró una imagen quística de gran tamaño en el pulmón derecho. Una vez recuperado de la bronquiolitis, se resecó quirúrgicamente. Se encontró un quiste localizado en el extremo superior del lóbulo inferior derecho que desplazaba el mediastino a izquierda y colapsaba los lóbulos medio y superior. La biopsia confirmó quiste pulmonar congénito con fibrosis cicatricial, hemorragia antigua e inflamación crónica inespecífica. El cultivo del líquido interior fue negativo. El lactante no ha vuelto a presentar síntomas respiratorios durante cuatro años después de la cirugía. Se analiza el origen, diagnóstico y manejo de los quistes broncogénicos en la infancia. Se enfatiza la importancia de la radiografía de tórax en niños con síntomas respiratoriosBronchogenic cysts are rarely diagnosed in the newborn period. It is a benign congenital anomaly of the embrionic system. We report the case of a 10 month old infant who was admitted to the hospital with a moderate bronchiolitis caused by influenza A, with cough, wheezing, fever and vomiting. Chest X-ray showed a large cyst in the right lung. He had a good evolution with only supportive measures. After recovery the cyst was removed. At surgery, the cyst was located superiorly in the right lower lobe, with left mediastinal shift and collapsed upper and middle lobes. Pathologic examination of the specimen revealed a congenital cyst with fibrosis, old hemorrhage and nonspecific inflammation. No bacterial growth was found. The infant has been symptom free during 4 years of follow-up. We review the pathogenesis, diagnosis and treatment of bronchogenic cysts in childhood and emphasize the importance of chest radiographs in bronchiolitis and chronic cough

  5. Equinococosis humana (quiste hidatidico): dos casos

    OpenAIRE

    Lichtenberger, Egon

    2011-01-01

    Se describen dos casos de quiste indatídico hepático en pacientes colombianos, oriundos del Chocó y de la Guajira, respectivamente. La equinococosis es posiblemente más frecuente en Colombia de lo que comúnmente se supone. Se hace un corto resumen de la anatomía patológica, morfología, ciclo vital, epidemiología y medios diagnósticos de esta parasitosis.The author describes two cases of hepatic echinococcosis demonstrating again, as correa henao and bojanini have done before, that this parasi...

  6. Cáncer de quiste en conducto tirogloso

    Directory of Open Access Journals (Sweden)

    Manuel Francisco Jiménez-Navarrete

    2013-12-01

    Full Text Available El quiste del conducto tirogloso es una de las anomalías del desarrollo que se presentan más frecuentemente en el cuello. La presencia en este de carcinoma aislado o concomitante con cáncer en tiroides, es muy infrecuente. Se expone aquí el caso de una paciente joven que se presentó con esta entidad. Se describe su presentación y manejo. Actualmente sigue su control en el Servicio de Endocrinología del Hospital San Vicente de Paúl, Heredia, Costa Rica.

  7. Unusual Cases of Epidermoid cyst: Case Series

    Directory of Open Access Journals (Sweden)

    Lalita Yadav

    2013-09-01

    Full Text Available In the oro-facial region cystic lesions of different etiologies are encountered owing to the presence of the teeth in the jaw bones. A bewildering variety of developmental, odontogenic and non-odontogenic cysts are seen. Epidermoid cyst is a rare developmental cyst of the oro-facial region which results from entrapped epidermal elements without adnexal appendages. Dermoid and epidermoid cysts occur in oro-facial region with an incidence of 6.9-7% and represents less than 0.01% of all oral cavity cysts. Here we report two cases of epidermoid cysts occurring at unusual locations involving upper left maxillary region lateral to the nose and pinna of the ear.

  8. Suprasellar epidermoid presenting with precocious puberty

    Directory of Open Access Journals (Sweden)

    Nigel Peter Symss

    2007-01-01

    Full Text Available Epidermoids are inclusion tumors of the central nervous system and are rare, benign slow-growing tumors. They are estimated to constitute 0.5-1.8% of the brain tumors and have an affinity for the subarachnoid cisterns at the base of the brain, the suprasellar cistern being one of the most favoured sites. We report a case of suprasellar epidermoid in a 2-year-old male child with an unusual CT and MRI appearance, who presented to us in February 1995 with features of precocious puberty. In October 2004, at the age of 11 years, he presented with symptoms and signs of raised ICP.

  9. Testicular varicoceles

    Energy Technology Data Exchange (ETDEWEB)

    Beddy, P. [Department of Radiology, Adelaide and Meath Hospital, Tallaght, Dublin 24 (Ireland); Geoghegan, T. [Department of Radiology, The Adelaide and Meath Hospital, Tallaght, Dublin 24 (Ireland); Browne, R.F. [Department of Radiology, The Adelaide and Meath Hospital, Tallaght, Dublin 24 (Ireland); Torreggiani, W.C. [Department of Radiology, The Adelaide and Meath Hospital, Tallaght, Dublin 24 (Ireland)]. E-mail: william.torreggiani@amnch.ie

    2005-12-15

    A testicular varicocele represents an abnormal degree of venous dilatation of the pampiniform plexus. It is a relatively common condition and may present at scrotal pain and swelling. An association with male subfertility is an area of debate. This article describes the present day radiological criteria and imaging techniques to aid accurate diagnosis of varicoceles. In addition, the role of the interventional radiologist in treating this condition is discussed.

  10. Epidermoid cyst of clitoris mimicking clitoromegaly

    Directory of Open Access Journals (Sweden)

    Aggarwal Satish

    2010-01-01

    Full Text Available Clitoromegaly in pediatric and adolescent age group is usually indicative of a disorder of sexual differentiation. We report a girl child presenting with clitoral enlargement due to an epidermoid cyst. The cyst was excised with complete cosmetic recovery.

  11. Pineal epidermoid cyst: its surgical therapy.

    Science.gov (United States)

    McDonnell, D E

    1977-06-01

    A pineal epidermoid cyst was initially diagnosed as a pinealoma. Seven years later combined computerized axial tomography and carotid-vertebral angiography accurately delineated the location and suggested the diagnosis of this histologically benign lesion. Microsurgical technique via a right occipital transtentorial approach allowed successful intracapsular resection of this tumor. PMID:882913

  12. Quistes pulmonares congénitos / Congenital lung cysts

    Scientific Electronic Library Online (English)

    Nuvia, Suárez García; Sergio Germán, Piloña Ruiz; Omar León, Vara Cuesta; Rita Inés, Milians Casanova; Mirka, Rosa Torres.

    2014-06-01

    Full Text Available Introducción: las malformaciones pulmonares congénitas constituyen una alteración en el desarrollo embriológico y fetal de las distintas estructuras pulmonares y una rara expresión de estas son los quistes pulmonares congénitos. Caso clínico: se presenta un recién nacido a término, de buen peso, asi [...] ntomático y estable hasta el tercer día de vida al debutar con un estado de shock séptico secundario, de bronconeumonía complicada con derrame pleural derecho. En los estudios evolutivos hacia el cuarto de día de vida se le diagnostica como hallazgo radiológico la presencia de quistes pulmonares que evolucionan de forma asintomática. Después de una valoración multidisciplinaria es egresado con un seguimiento por su condición de alto riesgo. Actualmente saludable y con buen desarrollo psicomotor. Conclusiones: la importancia del tema que se presenta es que se describe una presentación rara de quistes pulmonares congénitos en un recién nacido que desarrolló un estadio avanzado de sepsis. Abstract in english Introduction: congenital lung malformations constitute an alteration in the embryonic and fetal development of the different lung structures and a rare expression of these congenital lung cysts. Case report: termed newborn, good weight, evolving asymptomatic and stable until the third day of life to [...] debut a state of septic shock secondary to complicated bronchopneumonia with right pleural effusion. In evolutionary studies by the fourth day of life it is diagnosed, as radiological finding, the presence of lung cysts evolving asymptomatically. After a multidisciplinary assessment there is a graduate tracking of their status, with high risk. Currently healthy and good psychomotor development. Conclusions: the importance of the issue presented is a rare presentation of congenital lung cysts in a newborn who developed an advanced stage of sepsis described.

  13. Quiste esplénico abscedado: reporte de un caso

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    Roxana Montenegro

    2003-12-01

    Full Text Available Los autores reportan un raro caso de un absceso esplénico crónico, en un paciente varón de 52 años de edad; a quien dos años antes de su ingreso al hospital se le diagnosticó en forma casual -diagnóstico por imágenes- un quiste esplénico con paredes calcificadas, estando previamente asintomático. Al momento de su ingreso se presentó con una historia de 12 meses de dolor leve en cuadrante superior izquierdo del abdomen como única manifestación positiva. Luego de una intervención quirúrgica, el diagnóstico correspondió a un absceso esplénico crónico o seudoquiste esplénico por los hallazgos anatomopatológicos. Se describe las características del caso y se revisa la literatura.

  14. Presentación inusual de los quistes aracnoideos

    Scientific Electronic Library Online (English)

    Fidel, Sosa; Facundo, Rodríguez; Fernando, Palma; Graciela, Zuccaro.

    2006-09-01

    Full Text Available Objetivo. Describir y analizar la asociación entre quistes aracnoideos e higroma subdural. Esta es considerada una complicación excepcional, con sólo 24 casos reportados en la literatura, siendo de cinco casos la serie publicada más numerosa. Método. Se realizó el análisis retrospectivo de las histo [...] rias clínicas de 5 pacientes portadores de quiste aracnoideo, en los que la forma de presentación consistió en higroma subdural e hipertensión endocraneana. Resultados. El rango de edad fue entre 3 y 15 años (promedio: 7 años). La relación M/F fue 3/2. En 3 casos los síntomas se presentaron después de un traumatismo encefalocraneal leve y en los 2 restantes fue espontáneo. Todos se manifestaron con síntomas de hipertensión endocraneana y edema de papila bilateral, en 2 de ellos se constató paresia del VI par izquierdo. A todos se les realizó TAC y en 2 casos IRM. En los 5 pacientes se constató un higroma subdural con efecto de masa y quiste aracnoideo de fosa media. Se realizó tratamiento quirúrgico de urgencia en los 5 casos. Todos los pacientes evolucionaron favorablemente con desaparición del higroma subdural. Actualmente se encuentran asintomáticos con un examen neurológico y fondo de ojo normal. Conclusión. Si bien el higroma subdural con hipertensión endocraneana es una complicación poco usual, debe ser tenida en cuenta como una de las formas de presentación clínica de los quistes aracnoideos, la cual requiere inmediata resolución quirúrgica. Abstract in english Objetive: To analyze and describe the association between arachnoid cysts and subdural hygroma. This association is an unusual complication of which only 24 cases have been reported in the literature. Methods: The clinical records of 5 patients with arachnoid cysts presenting as a subdural hygroma w [...] ith increased intracranial pressure were analyzed retrospectively. Results: The ages of the patients ranged between 3 and 15 years (mean: 7 years). M/F ratio was 3/2. Onset of symptoms was postraumatic in 3 and spontaneous in 2. All patients presented symptoms of increased intracranial pressure and bilateral papilledema, and in 2 out of 5 paresis of the VI cranial nerve was found. All children underwent CAT scan and MRI was performedin 2. In all patients, subdural hygroma with mass effect and arachnoid cyst of the middle fossa was found. Emergency surgery was carried out in all cases. All patients evolved favorably with complete disappearance of the subdural hygroma. They are currently asymptomatic with normal neurological examination and fundoscopy. Conclusion: Even though subdural hygroma with increased intracranial pressure is an unusual complication, it should be known as one of the clinical presentations of arachnoid cysts, which required immediate surgical intervention.

  15. Quiste de erupcion en denticion mixta

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    Mileydis Esther Fernández Munive

    2013-10-01

    Full Text Available Title: Cyst of eruption in mixed dentition.ResumenLos quistes de erupción se presentan como áreas en la mucosa de levantamiento de volumen blando, de diferente coloración: azulado, rojo, vinaceo; mantiene un vaso presionado del que no solo sale agua, sino también sangre. Determinado como una variante del quiste dentígero, de origen odontogénico epitelial, diferentes porque este existe dentro del hueso; habitualmente en asociación con dientes próximos a erupcionar y en su gran mayoría relacionados con dentición mixta. En este caso clínico expuesto, la relación es con la erupción del diente 44, se muestra el abordaje y el control posoperatorio en el cual demuestra a través de fotografías la erupción adecuada del diente. (DUAZARY 2012 No. 2, 196 - 200AbstractThe cysts of eruption appear as areas in the mucous one of raising of soft volume, of different coloration: bluish, red, vinaceo; it keeps a glass pressed of the one that not only goes out waters down, but also bleed. Determined as a variant of the cyst dentígero, of origin odontogénic epitelial, different because this one exists inside the bone; habitually in association with near teeth to erupcionar and in his great majority related to mixed dentition. In this clinical exposed case, the relation is with the eruption of the tooth 44, the boarding and the control appears posoperatorio in which it demonstrates across photographies the suitable eruption of the tooth.Keywords: Tooth eruption; Odontogenic Cysts; Dentition Mixed. (MeSH.

  16. Carcinoma epidermoide en condilomatosis vulvoperineal gigante

    Scientific Electronic Library Online (English)

    Ana, Lizcano; Dulce, Puente; Jesus, Tata; Janette, Sholz; Jorge, Bittar.

    2006-12-01

    Full Text Available La condilomatosis vulvoperineal es una entidad muy frecuente en mujeres en edad reproductiva; recomendándose realizar la tipificación del virus papiloma humano, dada la relación de algunos subtipos con el carcinoma epidermoide a nivel ginecológico. Se presenta el caso de una paciente femenina de 39 [...] años que consultó por presentar una lesión exofítica, verrugosa que ocupa labios mayores y menores de la vulva, clítoris, introito vaginal y región perianal; de la cual se toma biopsia incisional reportando papilomatosis por virus papiloma humano, sin evidencia de atipias. Se lleva a quirófano realizando dermovulvectomía, cuya biopsia definitiva reportó carcinoma epidermoide invasor bien diferenciado, focal, con bordes resección libres; se completa con disección inguinal bilateral superficial y profunda sin evidencia de lesión metastásica ganglionar. Se realizó tipificación viral por reacción de cadena de polimerasa resultando VPH 16. A 20 meses de seguimiento, no hay evidencia clínica ni citológica de lesión recurrente. Es importante realizar la tipificación viral de estas lesiones por su relación con el carcinoma epidermoide de la vulva. Se realizó una revisión de la literatura. Abstract in english The vulvoperineal condylomatosis it’s a very frequent disease in reproductive age young women; it’s recommended to realize the viral typification, because the relation between some human papillomavirus subtypes with gynaecology epidermoid cancer. We present the case of a 39 years old female patient [...] who consulted to present a exofitic injury, warty that occupies the majora and minora labia of the vulva, clitoris, vaginal vestibule and perianal region; from which incisional biopsy was taken, reporting papilomatosis by human papillomavirus, without evidence of atypias. Patient went to operating room to receive a dermovulvectomy, whose definitive biopsy reported invasive epidermoid carcinoma well differentiated, focal, with free resection margins; it is completed with superficial and deep bilateral inguinal dissection without evidence of metastasic nodal involment. Viral tipificación by reaction of polymerase chain reaction was made being VPH 16. To 20 months of fall up, there are not clinical or cytological evidence of recurrent lesions. It is important to make the viral tipificación of these lesions by its relation with the epidermoid carcinoma of the vulva. A revision of literature was made.

  17. Giant Pelvic Retroperitoneal Epidermoid Cyst: A Rare Case Report

    OpenAIRE

    Fdili Alaoui, F. Z.; Oussaden, A.; H. Bouguern; El Fatemi, H.; Melhouf, M. A.; A. Amarti; Ait Taleb, K.

    2012-01-01

    Epidermoid cyst is a frequent benign cutaneous tumor. The pelvic localization does not occur very often. The literature that taps into such cases is very limited in scope. Here is a report of a 27-year-old woman with a giant pelvic retroperitoneal epidermoid cyst. The use of ultrasound exploration and computed tomography has indicated ovarian origins. The surgery also revealed a retroperitoneal epidermoid cyst, uterus and ovaries were all intact. The evacuation of a cyst was found to contain ...

  18. Sublingual epidermoid cyst: a case report

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    Kandogan Tolga

    2007-09-01

    Full Text Available Abstract Epidermoid and dermoid cysts represent less than 0.01% of all oral cavity cysts. The cysts can be defined as epidermoid when the lining presents only epithelium, dermoid cysts when skin adnexa are found, and teratoid cysts when other tissue such as muscle, cartilage, and bone are present. In this article, we present the case of an epidermoid cyst, with an oral as well as a submental component, in an 11 year old boy who presented with complaints of a mass in the oral cavity, difficulty chewing and swallowing of solid foods for about 3 years. He was admitted to the otolaryngology department. On examination, a mass displacing the tongue superiorly and posteriorly was noticed. An MRI scan was done and showed a 40 × 35 mm well-circumscribed non-enhancing cystic mass extending from the sublingual area to the level of the thyroid notch. The content of the cyst was homogenous. On examining the neck, a firm swelling was also noticed in the submental area, extending down to the thyroid notch. Under general anesthesia and with nasotracheal intubation, the patient underwent surgical removal of the mass. Extraorally, a midline submental horizontal incision was performed through the mucosa overlying the swelling and the cyst was dissected from the surrounding tissues and removed. On histological examination, acidophilic stratum corneum and basophilic dot like staining of stratum granulosum, which is the hallmark of an epidermoid cyst, were seen. The patient did well postoperatively, and no recurrence was noticed at the 6-months follow-up.

  19. Orbital dermoid and epidermoid cysts: Case study

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    Veselinovi? Dragan

    2010-01-01

    Full Text Available Introduction. Dermoid and epidermoid cysts of the orbit belong to choristomas, tumours that originate from the aberrant primordial tissue. Clinically, they manifest as cystic movable formations mostly localized in the upper temporal quadrant of the orbit. They are described as both superficial and deep formations with most frequently slow intermittent growth. Apart from aesthetic effects, during their growth, dermoid and epidermoid cysts can cause disturbances in the eye motility, and in rare cases, also an optical nerve compression syndrome. Case Outline. In this paper, we described a child with a congenital orbital dermoid cyst localized in the upper-nasal quadrant that was showing signs of a gradual enlargement and progression. The computerized tomography revealed a cyst of 1.5-2.0 cm in size. At the Maxillofacial Surgery Hospital in Niš, the dermoid cyst was extirpated in toto after orbitotomy performed by superciliary approach. Postoperative course was uneventful, without inflammation signs, and after two weeks excellent functional and aesthetic effects were achieved. Conclusion. Before the decision to treat the dermoid and epidermoid cysts operatively, a detailed diagnostic procedure was necessary to be done in order to locate the cyst precisely and determine its size and possible propagation into the surrounding periorbital structures. Apart from cosmetic indications, operative procedures are recommended in the case of cysts with constant progressions, which cause the pressure to the eye lobe, lead to motility disturbances and indirectly compress the optical nerve and branches of the cranial nerves III, IV and VI.

  20. Quiste óseo aneurismático simulando tumoración de rinofaringe

    Scientific Electronic Library Online (English)

    Alirio, Mijares B; Carmen M, Suárez; Nelson, Urdaneta L; Leonardo, Badell; Salvador, Somaza; Dilmeri, Castro.

    2011-06-01

    Full Text Available Los quistes óseos aneurismáticos del área de cabeza y cuello representan menos del 5 % de todos los tumores óseos. Son lesiones benignas, que comúnmente afectan las metáfisis de los huesos largos y las vértebras como en el caso que se describe a continuación, simulando una lesión de la rinofaringe. [...] Se describe su manejo y tratamiento. Abstract in english The aneurismal of bone cyst of the head and neck localization, represent less than the 5 % of the all bone tumors. They are benign lesions, and commonly affecting the metaphysis of the long bones and vertebrae, like in the case we described below, it simulating the rhino pharynx lesion. We describe [...] the management and treatment.

  1. Testicular Torsion (For Parents)

    Science.gov (United States)

    ... to Z: Scrotal Pain, Acute A to Z: Varicocele (Scrotal Varices) Hernias Ultrasound: Scrotum Undescended Testicles Male ... Exams How to Perform a Testicular Self-Examination Varicocele Male Reproductive System Testicular Torsion Contact Us Print ...

  2. Testicular germinal tumors

    International Nuclear Information System (INIS)

    This work is about diagnosis, treatment and monitoring of testicular germinal tumors. The presumed diagnosis is based in the anamnesis, clinical examination, testicular ultrasound and tumor markers. The definitive diagnosis is obtained through the inguinal radical orchidectomy

  3. Chemotherapy for Testicular Cancer

    Science.gov (United States)

    ... cancer Next Topic Radiation therapy for testicular cancer Chemotherapy for testicular cancer Chemotherapy (chemo) is the use of drugs to treat ... its side effects, please see, A Guide to Chemotherapy . Last Medical Review: 01/20/2015 Last Revised: ...

  4. CT scan findings of malignant epidermoid cyst

    International Nuclear Information System (INIS)

    The authors report a case of malignant epidermoid cyst (MEC) and discuss the characteristic findings on computed tomography (CT) scan, the differential diagnosis and the difference from the atypical findings of benign epidermoid cyst (BEC) with a review of the literature. A 60-year-old female complained of right oculomotor palsy and syncopal attacks. Plain CT scan revealed an irregularly low-density lesion with a ring-like and nodular high-density area mainly in the suprasellar cistern and midbrain, and another iso- to a slightly high-density area in the medial aspect of the right temporal lobe. On enhanced CT scan, a faint and inhomogeneous enhancement was observed in the lesion of the right temporal lobe. Surgical treatment was performed, and pathological examination of the specimen from the medial aspect of the right temporal lobe showed malignant change in the BEC. As a common and characteristic feature of CT scan findings of the present and the five previously reported cases, MEC shows homogeneous or inhomogeneous enhancement in the iso- to a slightly high-density lesion or the low-density lesion found in a typical BEC. (author)

  5. Epidermoid cysts of the pineal region.

    Science.gov (United States)

    MacKay, C I; Baeesa, S S; Ventureyra, E C

    1999-04-01

    Localization of epidermoid cysts to the pineal region is rare. The 7-year-old boy now reported presented with an 18-month history of progressive ataxia. CT and MRI scans demonstrated a 2.5x2.5 cm cyst at the pineal region with obstructive hydrocephalus. At surgery via an occipital transtentorial approach, a characteristic "pearly tumour" was encountered, and complete resection was achieved. We present the management of this child with pineal region epidermoid cyst and review 11 cases reported in the literature since 1968. In all, 8 of the 12 patients were males. The age at the time of diagnosis ranged from 7 years to 69 years. Parinaud's syndrome and hydrocephalus are the most common presenting findings. All but 1 patient underwent direct surgical resection; 1 had stereotactic decompression. Surgical treatment brought about complete resolution of the presenting symptoms and signs in 10 of the 12 cases. One patient had persistent upgaze palsy. One patient died from progression of the pineal region mass. This patient presented with hemiparesis, which is a marker of clinical aggressiveness. The authors advocate direct surgical attack as opposed to stereotactic diagnosis and aspiration to: (1) obtain maximal resection and thereby limit the potential for recurrence and delayed complications of the cyst; (2) possibly avoid shunt placement in patients who present with hydrocephalus; and (3) decrease the likelihood of sampling error. PMID:10361967

  6. Oral Rehabilitation of a Patient with Cerebellopontine Angle Epidermoid Cyst

    Directory of Open Access Journals (Sweden)

    Amin Nourizadeh

    2015-01-01

    Full Text Available Epidermoid cysts are rare congenital tumors of the central nervous system (CNS, histologically benign and slow- growing lesions. Their frequency among primitive intracranial tumors is about 1% and they account for 40% of all intracranial epidermoid cysts of the cerebellopontine angle (CPA; the most common symptom which brings about difficulties in oral rehabilitation of these patients is facial weakness which diversely affects impression processes and use of prosthesis. We report the oral rehabilitation of a patient with a cerebellopontine angle epidermoid cyst using neutral zone approach. Keywords: Soft tissue thickness; Facial reconstruction; Cone Beam Computed Tomography

  7. Estudio inmunohistoquímico del carcinoma epidermoide de labio / Epidermoid carcinoma of the lip: An immunohistochemical study

    Scientific Electronic Library Online (English)

    Belén, García-Montesinos Perea; José Fernando, Val Bernal; Ramón, Saiz Bustillo.

    2005-12-01

    Full Text Available Objetivos: Determinar la sobreexpresión de las proteínas c-erb-B2, p53, bcl-2, Ki67 y CD44varV6 y establecer su valor pronóstico en el carcinoma epidermoide de labio. Diseño del estudio: Estudio inmunohistoquímico de las proteínas p53, c-erb-B2, bcl-2, ki67 y CD44varV6 en 79 carcinomas epidermoides [...] de labio diagnosticados y tratados a lo largo de un periodo de 20 años. Los datos obtenidos fueron sometidos a análisis estadístico uni y multivariante. Resultados: La inmunotinción fue positiva en el 75% de los casos para la proteína c-erb-B2, en el 70,6% para la proteína p 53, en el 3,8% para la proteína bcl-2 y en el 89,9% para la molécula de adhesión cd44varV6. La expresión proteica de ki67 osciló entre un mínimo de 0% y un máximo de 6,29%. Los factores inmunohistoquímicos analizados no presentaron valor pronóstico en el carcinoma epidermoide de labio, y solamente los pacientes afectados por este tipo de tumores que expresaban la molécula de adhesión CD44varV6 se asociaron de forma significativa con una mayor supervivencia mediante el análisis de Kaplan-Meier. Conclusiones: Las técnicas inmunohistoquímicas analizadas para el estudio anatomopatológico del carcinoma epidermoide de labio no deberían realizarse rutinariamente, dado su mayor coste y su menor utilidad en la práctica clínica diaria. Abstract in english Objectives: To determine the expression of the c-erb-B2, p53, bcl-2, Ki67 and CD44varV6 proteins, and to establish their prognostic value in epidermoid carcinoma of the lip. Study design: Immunohistochemical study of the c-erb-B2, p53, bcl-2, Ki67 and CD44varV6 proteins in 79 epidermoid carcinomas o [...] f the lip, diagnosed and treated over a period of 20 years. The data obtained were subjected to uni- and multi-variate statistical analyses. Results: Immunostaining was positive in 75% of cases for c-erb-B2 protein, in 70.6% for p53 protein, in 3.8% for bcl-2 protein and in 89.9% for adhesion molecule CD44varV6. Ki67 protein expression varied between a minimum of 0% and a maximum of 6.29%. Most immunohistochemical factors analyzed presented no prognostic value for epidermoid carcinoma of the lip. Only those patients affected by this type of tumor that expressed the adhesion molecule CD44varV6 were significantly associated with a greater survival calculated by means of Kaplan-Meier analysis. Conclusions: The immunohistochemical techniques analyzed for the anatomicopathological study of epidermoid carcinoma of the lip should not routinely be used due to their high cost and low utility in daily clinical practice.

  8. Radiation Therapy for Testicular Cancer

    Science.gov (United States)

    ... chemo and stem cell transplant for testicular cancer Radiation therapy for testicular cancer Radiation therapy uses high-energy rays or particles to ... cells or slow their growth. In testicular cancer, radiation is mainly used to kill cancer cells that ...

  9. Quiste dermoide en la cola de la ceja

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    Lázara Kenia Ramírez García

    2014-03-01

    Full Text Available El quiste dermoide es un tipo de coristoma que corresponde a una anomalía congénita del desarrollo. Se presenta una transicional de dos años. Desde su nacimiento, la mamá notó un aumento de volumen a nivel de la cola de la ceja del ojo derecho, de bordes delimitados, blanda, movible, reborde orbitario libre, sin cambios de coloración, con un crecimiento acelerado clínico y ultrasonográfico en meses. Se decidió exéresis y biopsia para estudio anatomopatológico. Los resultados finales mostraron confirmación del diagnóstico de quiste dermoide en la cola de la ceja. La evolución posoperatoria fue satisfactoria sin recidiva de la lesión.

  10. Quiste de ovario gigante. Presentación de un caso

    Directory of Open Access Journals (Sweden)

    Yarisdey Corrales Hernández

    2012-09-01

    Full Text Available Los quistes de ovario son tumoraciones frecuentes en las afecciones ginecológicas. Se presenta el   caso de una paciente de 46 años de edad, que acudió al Hospital General Universitario Dr. Gustavo Aldereguía Lima, de Cienfuegos, refiriendo dolor y aumento de volumen del abdomen de un año de evolución. Se realizaron examenes físico y ultrasonográfico, mediante los que se le diagnosticó una masa quística dependiente de ovario. Se practicó laparotomía y se resecó un quiste de ovario izquierdo. En su estudio anatomopatológico se comprobó el diagnóstico de cistoadenoma seroso del ovario.

  11. Varicocele and testicular function

    OpenAIRE

    Pastuszak, Alexander W.; Run Wang

    2015-01-01

    Testicular varicocele, a dilation of the veins of the pampiniform plexus thought to increase testicular temperature via venous congestion, is commonly associated with male infertility. Significant study has clarified the negative impact of varicocele on semen parameters and more recent work has shed light on its detrimental effects on the molecular and ultrastructural features of sperm and the testicular microenvironment, as well as more clearly defined the positive impacts of treatment on co...

  12. Intracranial epidermoid cyst in a horse.

    Science.gov (United States)

    Peters, M; Brandt, K; Wohlsein, P

    2003-07-01

    An intracranial epidermoid cyst was diagnosed in a Haflinger gelding aged 12 years suffering from episodes of neurological disturbance, apathy and fever. The extracerebral cyst was located in the region of the tentorium cerebelli and measured 9 x 8 x 5 cm. It displaced the cerebral hemispheres anteriorly and compressed the cerebellum and brainstem underneath. Histologically, the cyst was lined by keratinizing, stratified squamous epithelium and contained keratin scales, debris, focal haemorrhages, and degenerating inflammatory cells. The epithelium was supported by a vascularized fibrous capsule that firmly adhered to the dura mater. Multifocal haemorrhages and moderate lymphohistiocytic infiltrations were present in the capsule. The basement membrane was disrupted focally, and single or clustered cytokeratin-positive epithelial cells were detected in the fibrous capsule, suggesting a possible transition to malignancy. PMID:12859913

  13. Concomitant occurrence of vestibular schwannoma and epidermoid tumor

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    B V Savitr Sastri

    2013-01-01

    Full Text Available The occurrence of two tumors adjacent to each other at the same site is very rare. We present here, a patient with a vestibular schwannoma found adjacent to an epidermoid tumor in the cerebellopontine angle.

  14. Pineal epidermoid cyst: case report and review of the literature.

    Science.gov (United States)

    Hassani, Fahd Derkaoui; Bouchaouch, Abdelali; El Fatemi, Nizare; Gana, Rachid; El Abbadi, Najia; Maaqili, Moulay Rachid

    2014-01-01

    Intracranial epidermoid cysts are one of the rare tumors of all intracranial tumors. They represent 0,2 to 1% of intracranial tumors and 7% of tumors in the cerebellopontine angle. The pineal region is exceptionally subject to such kind of tumor. Cushing was the first to report the pineal localization of the epidermoid cyst in 1928. Up to now, 85 cases of pineal epidermoid cyst were cited in the literature. We report a clinical case concerning a 45 years old man who presented an intracranial hypertension during 18 months. The clinical examination found a hemiparesis with a facial hypoesthesis. The MRI showed a process of the pineal region. The patient underwent a surgery with a large resection. The histological examination confirms the epidermoid cyst. Many approaches were described in the literature. The outcome is related to this localization. PMID:25489364

  15. QUISTES NO NEOPLÁSICOS Y NEOPLÁSICOS DE OVARIO EN EDAD PEDIÁTRICA

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    José Raúl Sánchez Aguilar

    2006-01-01

    Full Text Available En Cuba los tumores y quistes de ovario en la infancia ocupan aproximadamente el 1% de todos los procesos tumorales, durante esta etapa de la vida, más del 50 % de estos tumores corresponden como quistes simples, teratomas benignos, y quistes foliculares, por lo que se realizó un estudio retrospectivo longitudinal en niños con incidencias de estos tumores en el Hospital Pediátrico ¿Eduardo Agramonte Piña¿, Camagüey, desde julio de 1973 a julio de 2004, con el objetivo de valorar la incidencia de estos tumores en niños. El universo y muestra lo constituyeron los 170 pacientes ingresados por dicha enfermedad. Se revisaron las historias clínicas de los enfermos. Se confeccionó un formulario que incluyó variables como. la edad, la forma de presentación, el lado más afecto, el histología, los complementarios realizados y las complicaciones, donde predominó el rango de edad entre los 11y15 años con 122 pacientes para un 71.8 %. Existió un aumento de la incidencia en el ovario derecho para un 71.8 %. Las lesiones de mayor prevalencia fueron los tumores quísticos benignos (teratomas quísticos con 107 de los pacientes, seguido de los quistes no neoplásicos (foliculares para un 12.4 %.El Rx simple de abdomen y el USG abdominal fueron los complementarios de mayor utilidad.

  16. Quiste óseo aneurismático de la rótula: Presentación de un caso

    Scientific Electronic Library Online (English)

    GASTON, ARANGO GARCIA; EDDY, SANCHEZ NODA; RODRIGO, ALVAREZ LORENZO; RICARDO, TARRAGONA REINOSO.

    1995-12-01

    Full Text Available Se presenta un paciente con un quiste óseo aneurismático en la rótula, lo que constituye una localización muy atípica. Se expone la sintomatología clínica, así como la novedosa combinación de la biopsia ósea y la artroscopia para evaluar mejor la articulación y el tratamiento practicado, que consist [...] ió en la patelectomía con la técnica de Boyd.

  17. Quistes renales: concepto y clasificación / Renal cysts: concept and classification

    Scientific Electronic Library Online (English)

    Sandalio, Durán Álvarez.

    2007-03-01

    Full Text Available Con la finalidad de poder ayudar a los estudiantes de medicina y médicos generales básicos, se hace una breve revisión sobre los quistes renales, tanto de los que constituyen una enfermedad por sí mismos como de los que pueden estar asociados a diferentes síndromes y los que pueden aparecer evolutiv [...] amente en el curso de una enfermedad renal. Conocer las causas principales que producen quistes renales es esencial para el correcto asesoramiento genético. Consideramos que esta clasificación, aunque no perfecta ni completa, puede ser útil en la práctica médica. En ella se trata de agrupar en primer lugar a las enfermedades con herencia dominante o recesiva, y además a los quistes asociados a síndromes malformativos, las alteraciones cromosómicas que pueden tener quistes renales y los quistes no genéticos que pueden ser congénitos o adquiridos. Abstract in english To help medical students and basic general physicians, a brief review is made on renal cysts, including those that are a disease by themselves, the associated with different syndromes, and the ones that may appear evolutively in the course of a renal disease. Knowing the main causes of renal cysts i [...] s essential for an appropriate genetic counselling. We consider that this classification, although it is neither perfect nor complete, may be useful in medical practice. An effort is made to group in it , in the first place, the diseases with dominant or recessive inheritance, the cysts associated with malformation syndromes, the chromosomal disorders that may have renal cysts, and the nongenetic cysts that may be congenital or acquired.

  18. Epidermoid cyst of the posterior fossa: a case report / Cisto epidermoide da fossa posterior: relato de caso

    Scientific Electronic Library Online (English)

    Eduardo, Cambruzzi; Karinelli, Presa; Luciano Carvalho, Silveira; Gerson Evandro, Perondi.

    2011-02-01

    Full Text Available Os cistos epidermoides do sistema nervoso central (SNC) são condições incomuns, estando localizados mais frequentemente no ângulo pontocerebelar e ao redor da ponte. Eles são revestidos por epitélio escamoso queratinizado e lamelas de queratina, tornando seu conteúdo branco-perolado e pastoso. Os ci [...] stos epidermoides são, na maioria das vezes, originados de malformações, possivelmente associados ao entremeio de elementos superficiais do ectoderma do SNC durante o fechamento da placa neural, ou formação das vesículas cerebrais secundárias. Os autores descrevem um caso de cisto epidermoide da fossa posterior determinando hidrocefalia e revisam critérios morfológicos e diagnósticos dessa lesão. Abstract in english Epidermoid cysts of the central nervous system are uncommon conditions, which are frequently located in the cerebellopontine angle and around the pons. They are covered with keratinized squamous epithelium and keratin lamella, which give its contents a soft, white-pearly appearance. Epidermoid cysts [...] are mostly originated from malformations, presumably associated with surface elements of the nervous system ectoderm during the closure of the neural groove or formation of secondary cerebral vesicles. The authors describe a case of epidermoid cyst in the posterior fossa causing hydrocephalus and review morphologic and diagnostic criteria of this lesion.

  19. Quiste óseo aneurismático Aneurysmal bone cyst

    Directory of Open Access Journals (Sweden)

    Ferdinando de Conto

    2012-06-01

    Full Text Available El quiste óseo aneurismático (QOA es una lesión benigna rara en huesos maxilares, su mayor frecuencia es en huesos largos del esqueleto y columna vertebral. Algunos autores especulan que el origen sea por trauma, mala formación o un neoplasma. El aspecto radiográfico puede mostrar desde una imagen difusa hasta una imagen bien definida, muy semejante a las otras lesiones de los maxilares volviendo el diagnóstico diferencial amplio. Con la destrucción del córtex óseo puede todavía formar una imagen reaccional del periostio en forma de rayos de sol, característico de una lesión maligna. En este estudio, se presenta caso de paciente femenino, 17 años de edad, que buscó el Servicio de Cirugía y Traumatología Buco maxilofacial del Hospital São Vicente de Paulo-RS, que presentó dolor y aumento de volumen en la mandíbula. Informó que hace cerca de un año empezó a sentir malestar en la región junto al ángulo mandibular derecho, lo cual fue progresivamente aumentando de volumen. El aspecto radiográfico acordaba una lesión maligna. Después de la confirmación histopatológica de QOA, el tratamiento seleccionado para el caso fue quirúrgico conservador, con legrado de la cavidad ósea, y fue mantenido en control posoperatorio de rutina con 6 y 18 meses. En las radiografías panorámicas realizadas se verifica la neoformación ósea y cura del caso.The aneurysmal bone cyst (ABC is a benign and rare lesion in maxillary bones, is more frequent in largo bones of skeletal and spinal column. Some authors speculate about that its origin be traumatic, malformation of neoplasm. The radiographic appearance may to show from a diffuse image up to a well defined image very similar to the other maxillary lesions turning wide the differential diagnosis. With destruction of the bon cortex it is possible to create a reaction image of periosteum in sunbeams characteristic of malignant lesion. This is the case of a female patient aged 17 seeking help in the Bucco-maxillofacial Surgery and Traumatology Service of the São Vicente de Paulo Hospital _ RS, presenting with pain and an increased mandibular volume. She manifested that around one year she began to feel a discomfort next to he right mandibular angle, which was progressively increasing the volume. The radiographic appearance resembled a malignant lesion. After the histopathology verification of ABC, treatment choosed for this case was of type conservative surgical with bone cavity curettage and was maintained under systemic postoperative control for 6 and 18 months. In the taken panoramic radiographies is verified the bone neoformation and the cure of case.

  20. Dislocación testicular postraumática / Traumatic testicular dislocation

    Scientific Electronic Library Online (English)

    S., Luján Marco; A., Budía Alba; V., Bango García; M., Ramirez Backhaus; F.J., Delgado Oliva; J.F., Jiménez Cruz.

    2006-04-01

    Full Text Available Presentamos el caso clínico de un paciente politraumatizado, conductor de motocicleta, con dislocación testicular derecha. Se trata de una lesión infrecuente tras traumatismo contuso que requiere diagnóstico y tratamiento precoz con el fin de evitar la atrofia testicular. Esta lesión deberá tenerse [...] en cuenta en toda evaluación del politraumatizado, requiriendo tratamiento quirúrgico. El objetivo del caso clínico es aportar un nuevo caso a la literatura, siendo este el sexto caso publicado por autores españoles, con el fin de clarificar el manejo y tratamiento. Abstract in english Testicular dislocation is an uncommon injury after blunt scrotal trauma (with only 150 cases reported) that must be properly diagnosed and treat in order to avoid a testicular atrophy. We presented a case report of traumatic dislocation of right testicle after a motorcycle accident. This type of tes [...] ticular injury should be included in the whole evaluation of every polytrauma patient and usually requires a surgical treatment. The aim of this report is to clarify some aspects of the management of such rare entity.

  1. Epidermóide intra-raqueano / Intraspinal epidermoid

    Scientific Electronic Library Online (English)

    Antonio B., Lefèvre; Rolando A., Tenuto; Amelia T. M., Vasconcelos.

    1957-03-01

    Full Text Available Caso de tumor epidermóides intra-raqueano, extra-medular ao nível de T12, diagnosticado e tratado cirùrgicamente, em um menino de 9 anos. Os autores chamam a atenção para a dificuldade diagnostica deste caso, cujo quadro clínico lembrava o de uma radiculopatia compressiva por hérnia de disco interve [...] rtebral. A evolução foi favorável, com recuperação total, sem seqüelas. Lembram os autores a necessidade de ser precizada a designação dêsses tumores, que são muitas vêzes confundidos com os cistos dermóides e outros tumores congênitos. Abstract in english Case report of an intradural, extramedullary epidermoid tumor, at the level of T12, in a 9 year old boy, treated surgically. The authors stress the difficulty to diagnose this case, for the clinical picture seemed that of a radiculopaty due to compression by an intervertebral herniated disc. The evo [...] - lution was favorable, with complete recuperation and without sequelae. The authors point out the necessity of defining the designation of these tumors, often confused with dermoid cysts and other congenital tumors.

  2. Epidermoid cyst of the ovay in young woman: A case report

    International Nuclear Information System (INIS)

    In general, ovarian epidermoid cysts coexist with surface epithelial ovarian tumors. Pure epidermoid cysts are extremely rare diseases, comprising less than 1% of surface ovarian tumors. We present here a pathologically proven epidermoid cyst of the ovary in a young woman with ultrasonographic and magnetic resonance findings

  3. Epidermoid cyst of the ovay in young woman: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Jung Hee; Kim, See Hyung; Kang, Yu Na; Kim, Mi Jeong [Keimyung University School of Medicine, Dongsan Medical Center, Daegu (Korea, Republic of)

    2015-06-15

    In general, ovarian epidermoid cysts coexist with surface epithelial ovarian tumors. Pure epidermoid cysts are extremely rare diseases, comprising less than 1% of surface ovarian tumors. We present here a pathologically proven epidermoid cyst of the ovary in a young woman with ultrasonographic and magnetic resonance findings.

  4. Testicular Cancer Resource Center

    Science.gov (United States)

    ... visit to the doctor TC Links & Articles - A virtual library of Testicular Cancer Info Search the TCRC - ... they do and how it works Chemotherapy - Some call it weed killer, others call it a life ...

  5. Intraosseous epidermoid cyst of the finger phalanx: a case report

    Directory of Open Access Journals (Sweden)

    Nipun Kalsotra

    2010-09-01

    Full Text Available Nipun Kalsotra, Manjeet Singh, Siddhartha Sharma, Dara SinghDepartment of Orthopaedics, Government Medical College Jammu, Jammu and Kashmir State, IndiaAbstract: Epidermoid cysts of the finger phalanx are rare pseudotumors. They are benign lesions with a satisfactory outcome after excision. It is important to differentiate this benign lesion, which can be easily treated by curettage, from other benign and malignant lesions of the bone with a similar clinical presentation, and which may require amputation. We describe a case of an epidermoid cyst in the distal phalanx of the ring finger. It was treated successfully and the patient had excellent functional results at one-year follow-up.Keywords: finger phalanx, epidermoid cyst, lytic bone lesion

  6. Quiste Dentigero: Revisión bibliográfica y presentación de un caso

    Scientific Electronic Library Online (English)

    I, TAMI-MAURY; T, LOPEZ; Y, MOUSTARIH; N, MORETTA; G, MONTILLA; H, RIVERA.

    2000-06-01

    Full Text Available El Quiste Dentígero es el segundo quiste odontogénico más común. Generalmente está asociado con la corona de un diente normal impactado, usualmente con los terceros molares inferiores y caninos superiores. Frecuentemente se observa en pacientes del sexo masculino entre los 20 y 40 años de edad. Se p [...] resenta un caso clínico de un paciente de sexo masculino, de 53 años de edad. Se realizaron los respectivos estudios clínicos radiográficos e histopatológico. Clínicamente se observó una tumefacción no dolorosa relacionada con el canino inferior izquierdo impactado. Radiográficamente presentó un área radiolúcida multilocular de aproximadamente 7x3 centímetros de diámetro en la zona mencionada, preservando la cortical ósea. Se realizó la biopsia incisional. El diagnóstico histopatológico se correlacionó con los hallazgos clínicos y radiográficos, lo cual reveló un Quiste dentígero. Luego del diagnóstico final, la remoción quirúrgica del quiste fue llevada a cabo bajo anestesia local. Abstract in english Dentigerous cyst is the second most common odontogenic cyst. It is generally associated to a normal crown tooth usually impacted lower third molars and upper canine. It is frequently observed in male patients between 20 and 40 year-old. A clinical case of a 53 year-old male patient is presented. Cli [...] nical, radiological and histopathological studies were done. Clinically, a painless tumefaction involving the impacted mandibular left canine was noted. Radiological examination revealed a multilocular radiolucent area (7x3 centimeters in diameter), in the above mentioned location with preservation of cortical bone. Incisional biopsy was performed. The histopathological diagnosis correlated with the clinico-radiological findings disclosured a Dentigerous cyst. After final diagnosis of the leson, surgical removal of the cyst was carried out under local anesthesia.

  7. Giant Vulvar Epidermoid Cyst in an Adolescent Girl

    OpenAIRE

    Karaman, Erbil; Çim, Numan; Akdemir, Zülküf; Elçi, Erkan; Akdeniz, Hüseyin

    2015-01-01

    Introduction. Vulvar cyst in adolescent girls is very uncommon. Epidermoid cyst can be seen in many sites including face, trunk, and extremities but its occurrence in vulva is uncommon. This is the first case of epidermoid cyst of vulva reported in an adolescent girl. Case. A 17-year-old, adolescent girl admitted to our gynecology outpatient clinic with a complaint of painful and palpable mass in her vulva. On examination, a giant mass located in left vulva and labia majora with 11?cm in diam...

  8. Carcinoma en quiste tirogloso Carcinoma in thyroglosal duct cyst

    Directory of Open Access Journals (Sweden)

    M.E. Storani

    2010-09-01

    Full Text Available El carcinoma diferenciado de tiroides en quiste tirogloso (CaQT es una rara entidad. En diferentes series de pacientes operados por quistes tiroglosos su incidencia fue del 0.7 al 1.07%. Luego de la extirpación del quiste por el procedimiento de Sistrunk, no hay consenso sobre la indicación de tiroidectomía total, radioablación y/o terapéutica supresiva con levotiroxina. El objetivo del Departamento de tiroides de SAEM, fue evaluar: formas de presentación, evolución clínica, métodos diagnósticos de utilidad y tratamiento para consensuar futuras conductas. Material y Métodos: Estudio multicéntrico, retrospectivo en 22 pacientes entre 10 a 69 años, 15 mujeres y 7 varones. Resultados: El tamaño de los quistes osciló entre 1 y 8 cm (Mediana= 3.0 cm, ? ± DS= 3.7 ± 2.2 cm. La mitad de los pacientes presentó crecimiento del quiste en los 6 meses previos a la cirugía. La punción resultó sospechosa en 2/5 quistes y positiva en uno. La ecografía tiroidea evidenció nódulos en 4/13 casos (30%. Se realizó tiroidectomía en 17/22 pacientes (total: 15 y subtotal: 2. La histología del CaQT demostró carcinoma papilar en 21 y carcinoma folicular en uno. Hubo coexistencia de cáncer intratiroideo en el 23.5% de los casos, ninguno multicéntrico. Dos pacientes presentaron metástasis ganglionares y otro tuvo compromiso muscular (ninguno de ellos coexistió con cáncer intratiroideo. Se radioablacionó a 13 pacientes. En 9/11 pacientes la tiroglobulina permaneció indetectable durante el seguimiento (1 a 14 años. Conclusiones: 1 Realizar ecografía de cuello y punción ecoguiada a todo paciente con quiste tirogloso. 2 En caso de CaQT combinar simultáneamente tiroidectomía total y procedimiento de Sistrunk. 3 Evaluar radioablación complementaria y tratamiento supresivo con levotiroxina en cada caso. 4 Efectuar el seguimiento tal como en los carcinomas ortotópicos.Differentiated thyroid carcinoma (DTC in thyroglosal duct cyst (TGDC is rare, ranging from 0.7 to 1.07% in different series. After the surgery of choice (Sistrunk procedure the other alternative treatments such as thyroidectomy (Tx, radioiodine and L-T4 therapy are controversial. OBJECTIVE: to evaluate several and controversial aspects in the largest series of DTC in TGDC reported in the literature. Subjects and methods: retrospective multicentric study: n= 22, aged 10-69 yrs. (15 females and 7 men who underwent the Sistrunk procedure for TGDC. Results: none of the TGDC was less than 1 cm (median 3.0 cm, ?±SD= 3.7 ± 2.2cm. In half of them there was an increased cystic size in the last 6 months before surgery. Cyst FNA was suspicious in 2/5 and positive in one, whereas the histological diagnosis of the operated TGCD was papillary cancer in 21 and 1 follicular carcinoma. Thyroid ultrasound (US (n=13 showed nodules in 30% of the cases. Tx was performed in 17/22 (total: 15, subtotal: 2. Thyroid DTC coexisted in 4/17 (23.5%, and was unilateral in all of them. Lymph node metastases were present in 2 adults and muscle involvement was found in the 10-year old girl. None of these 3 patients had overt thyroid lesions. 131-I therapy was performed in 10 patients. In 9 out of 11 subjects Tg remained undetectable during follow-up (1-14yrs.. Persistent high Tg was present in one case without thyroid DTC. Conclusions: 1 Ultrasonography and FNAB should be performed to every patient with thyroglossal duct cyst 2 In case of TGDC, total Tx and Sistrunk's procedure should be simultaneously combined 3 131-I therapy and L-T4 suppressive treatment should be evaluated in every case 4 Follow-up as in the DTC.

  9. Carcinoma en quiste tirogloso / Carcinoma in thyroglosal duct cyst

    Scientific Electronic Library Online (English)

    M.E., Storani; A.M., Vázquez; G.N., Alcaraz; S., Gutiérrez; A., Gauna; M., Silva Croome; H., Niepomniszcze; M., Abalovich; C., Cabezón; S., Deutsch; A.M., Orlandi.

    2010-09-01

    Full Text Available El carcinoma diferenciado de tiroides en quiste tirogloso (CaQT) es una rara entidad. En diferentes series de pacientes operados por quistes tiroglosos su incidencia fue del 0.7 al 1.07%. Luego de la extirpación del quiste por el procedimiento de Sistrunk, no hay consenso sobre la indicación de tiro [...] idectomía total, radioablación y/o terapéutica supresiva con levotiroxina. El objetivo del Departamento de tiroides de SAEM, fue evaluar: formas de presentación, evolución clínica, métodos diagnósticos de utilidad y tratamiento para consensuar futuras conductas. Material y Métodos: Estudio multicéntrico, retrospectivo en 22 pacientes entre 10 a 69 años, 15 mujeres y 7 varones. Resultados: El tamaño de los quistes osciló entre 1 y 8 cm (Mediana= 3.0 cm, ? ± DS= 3.7 ± 2.2 cm). La mitad de los pacientes presentó crecimiento del quiste en los 6 meses previos a la cirugía. La punción resultó sospechosa en 2/5 quistes y positiva en uno. La ecografía tiroidea evidenció nódulos en 4/13 casos (30%). Se realizó tiroidectomía en 17/22 pacientes (total: 15 y subtotal: 2). La histología del CaQT demostró carcinoma papilar en 21 y carcinoma folicular en uno. Hubo coexistencia de cáncer intratiroideo en el 23.5% de los casos, ninguno multicéntrico. Dos pacientes presentaron metástasis ganglionares y otro tuvo compromiso muscular (ninguno de ellos coexistió con cáncer intratiroideo). Se radioablacionó a 13 pacientes. En 9/11 pacientes la tiroglobulina permaneció indetectable durante el seguimiento (1 a 14 años). Conclusiones: 1) Realizar ecografía de cuello y punción ecoguiada a todo paciente con quiste tirogloso. 2) En caso de CaQT combinar simultáneamente tiroidectomía total y procedimiento de Sistrunk. 3) Evaluar radioablación complementaria y tratamiento supresivo con levotiroxina en cada caso. 4) Efectuar el seguimiento tal como en los carcinomas ortotópicos. Abstract in english Differentiated thyroid carcinoma (DTC) in thyroglosal duct cyst (TGDC) is rare, ranging from 0.7 to 1.07% in different series. After the surgery of choice (Sistrunk procedure) the other alternative treatments such as thyroidectomy (Tx), radioiodine and L-T4 therapy are controversial. OBJECTIVE: to e [...] valuate several and controversial aspects in the largest series of DTC in TGDC reported in the literature. Subjects and methods: retrospective multicentric study: n= 22, aged 10-69 yrs. (15 females and 7 men) who underwent the Sistrunk procedure for TGDC. Results: none of the TGDC was less than 1 cm (median 3.0 cm, ?±SD= 3.7 ± 2.2cm). In half of them there was an increased cystic size in the last 6 months before surgery. Cyst FNA was suspicious in 2/5 and positive in one, whereas the histological diagnosis of the operated TGCD was papillary cancer in 21 and 1 follicular carcinoma. Thyroid ultrasound (US) (n=13) showed nodules in 30% of the cases. Tx was performed in 17/22 (total: 15, subtotal: 2). Thyroid DTC coexisted in 4/17 (23.5%), and was unilateral in all of them. Lymph node metastases were present in 2 adults and muscle involvement was found in the 10-year old girl. None of these 3 patients had overt thyroid lesions. 131-I therapy was performed in 10 patients. In 9 out of 11 subjects Tg remained undetectable during follow-up (1-14yrs.). Persistent high Tg was present in one case without thyroid DTC. Conclusions: 1) Ultrasonography and FNAB should be performed to every patient with thyroglossal duct cyst 2) In case of TGDC, total Tx and Sistrunk's procedure should be simultaneously combined 3) 131-I therapy and L-T4 suppressive treatment should be evaluated in every case 4) Follow-up as in the DTC.

  10. Segmental ischemia in testicular torsion

    OpenAIRE

    Tavasl?, Binnur; Köseo?lu, Hikmet; Çevik, Halime

    2016-01-01

    Testicular torsion is a rare but important entity in the discipline of urology, as urgent action is required to save the testicle anatomically and functionally. Occurring mainly in the young prepubertal or pubertal male, testicular torsion is also seen in young adults. The annual incidence has been estimated to be 4.5 cases per 100,000 male subjects. The outcome of testicular torsion, in cases of unsuccessful emergent intervention, is total or partial infarction of the testicular tissue. We p...

  11. Varicocele and testicular function

    Directory of Open Access Journals (Sweden)

    Alexander W Pastuszak

    2015-01-01

    Full Text Available Testicular varicocele, a dilation of the veins of the pampiniform plexus thought to increase testicular temperature via venous congestion, is commonly associated with male infertility. Significant study has clarified the negative impact of varicocele on semen parameters and more recent work has shed light on its detrimental effects on the molecular and ultrastructural features of sperm and the testicular microenvironment, as well as more clearly defined the positive impacts of treatment on couples? fertility. The relationship between varicocele and testicular endocrine function, while known for some time based on histologic evaluation, has become more apparent in the clinical setting with a growing link between varicocele and hypogonadism. Finally, in the pediatric setting, while future study will clarify the impact of varicocele on fertility and testicular function, recent work supports a parallel effect of varicocele in adolescents and adults, suggesting a re-evaluation of current treatment approaches in light of the progressive nature of the condition and potential increased risk of future disease.

  12. Epidermoid cyst of the ileum in a miniature dachshund dog.

    Science.gov (United States)

    Shimamura, Shunsuke; Kainuma, Risa; Kimura, Ken; Okamura, Yasuhiko; Kobayashi, Saori; Katayama, Masaaki; Sato, Reeko; Yasuda, Jun

    2014-04-01

    A 13-year-old castrated male miniature dachshund dog was presented with chronic vomiting and diarrhea. Contrast radiography and surgical exploration revealed an ileal cyst, which was excised. A diagnosis of epidermoid cyst was made from a combination of the clinical findings and histological examination of the surgical specimen. PMID:24688137

  13. Epidermoid cyst of the ileum in a miniature dachshund dog

    OpenAIRE

    Shimamura, Shunsuke; Kainuma, Risa; KIMURA, Ken; OKAMURA, Yasuhiko; KOBAYASHI, Saori; KATAYAMA, Masaaki; Sato, Reeko; Yasuda, Jun

    2014-01-01

    A 13-year-old castrated male miniature dachshund dog was presented with chronic vomiting and diarrhea. Contrast radiography and surgical exploration revealed an ileal cyst, which was excised. A diagnosis of epidermoid cyst was made from a combination of the clinical findings and histological examination of the surgical specimen.

  14. Epidermoid carcinomas of the conjunctive with intraorbital and intraocular invasion

    International Nuclear Information System (INIS)

    The epidermoid carcinomas of the conjunctive are tumors in general of low incidence with a range between 0.13 and 1.9 cases for 100,000 inhabitants; this incidence is superior however in tropical countries. The incidences reported for intra orbital and intraocular invasive forms have a range between 2 and 12% which demonstrates the aggressive character of this tumor. The handling of epidermoid carcinoma of the conjunctive in initial stages is very conservative, but in their natural history this tumor can invade the ocular globe, orbit, neighboring regions and distant organs, thereby of importance an early diagnosis and an appropriate treatment. Our objective was to know the incidence of epidermoid carcinoma of the conjunctiva with intraocular and intra orbital invasion in the Havana National Oncology Institute. We carry out a retrospective and descriptive study of 18 patients with clinical diagnoses and histology of epidermoid carcinoma of the conjunctiva with orbit infiltration assisted from January of 1995 until December 2003 classified as T4 NO MO. The evaluated parameters were: age, sex, initial treatment and evolution. Middle aged of our serie it was 58.7 years, excisional surgery and deep radiotherapy was the initial treatment applied in 83.33% of the cases. In its evolution eight cases (44.44%) of the patients had unfavorable result and radical surgery was carried out in 50% of the patients. (The author)

  15. Large and small cells non-keratinizing epidermoid vaginal carcinoma

    International Nuclear Information System (INIS)

    Five case reports of patients who were assisted at the cervix Pathology Department from 'Mariana Grajales Coello' Provincial Gynecological Obstetrical Hospital in Santiago de Cuba due to vaginal bleeding, low abdominal pain, leukorrhea and vaginal injuries are presented. The pathological study confirmed the diagnosis of squamous or epidermoid cells carcinoma

  16. Quistes epididimarios en la infancia / Epididymal cysts in childhood

    Scientific Electronic Library Online (English)

    Francisca Silvia, Chillón Sempere; Carlos, Domínguez Hinarejos; Agustín, Serrano Durbá; Francisco, Estornell Moragues; Mario, Martínez-Verduch; Francisco, García Ibarra.

    2005-05-01

    Full Text Available OBJETIVO: Hemos realizado una revisión retrospectiva de los casos atendidos en los últimos 5 años; se han recogido un total de 15 casos. Los quistes simples de epidídimo son patología poco frecuente en la infancia diagnosticándose la mayoría en la pubertad. Actualmente y debido a la escasa casuístic [...] a no existe consenso en la terapéutica más adecuada. METODOS/RESULTADOS: La edad media de presentación fue de 11,5 años (1-16). El 50% fueron diagnosticados de forma incidental y un 29% cursó con aumento de tamaño escrotal. El 46% de los casos presentaban varicocele izquierdo asociado (n=6) y un 26% presentaba antecedentes de orquiepididimitis. El diagnóstico se basó en la exploración física con confirmación ecográfica. Un 40 % fue tratado quirúrgicamente y el resto fue subsidiario de tratamiento conservador sin constatarse la presencia de complicaciones en estos en los controles posteriores. CONCLUSIONES: Dada la benignidad y la buena evolución de todos los casos de quistes de epidídimo tratados de forma conservadora, y la ausencia de beneficio con el tratamiento quirúrgico, creemos que el tratamiento debe ser conservador con controles clínicos y ecográficos reservando el tratamiento quirúrgico para aquellos quistes que presenten complicaciones. La frecuente asociación encontrada entre el quiste epididimario y el varicocele responde a una coincidencia de ambas patologías en la edad peripuberal. Abstract in english OBJECTIVES: To retrospectively review all cases of epididymal cysts registered over the last five years; 15 cases have been included. Simple epididymal cysts are a rare pathology in childhood, being most of them diagnosed in puberty. Currently, due to the scarce case series, there is not consensus a [...] bout the most adequate therapy. METHODS/RESULTS: Mean age at presentation was 11.5 yr. (1-16). 50% were diagnosed incidentally and 29% presented increased scrotal size. 46% of the cases had associated left varicocele (n = 6) and 26% had history of orchiepididymitis. Diagnosis was based on physical examination and confirmed by ultrasound. 40% of the patients underwent surgery and the remainder received conservative treatment without evidence of complications on follow-up. CONCLUSIONS: Due to the benign character and good evolution of all cases of epididymal cysts treated conservatively and the absence of benefit after surgical treatment, we believe that management should be conservative with clinical and ultrasound controls, leaving surgery for cysts with complications. The frequent association between epididymal cysts and varicocele is related to coincidence of both pathologies in the prepuberal age.

  17. Testicular Cancer and Cryptorchidism

    Directory of Open Access Journals (Sweden)

    AlexanderIAgoulnik

    2013-03-01

    Full Text Available The failure of testicular descent or cryptorchidism is the most common defect in newborn boys. The descent of the testes during development is controlled by insulin-like 3 peptide and steroid hormones produced in testicular Leydig cells, as well as by various genetic and developmental factors. While in some cases the association with genetic abnormalities and environmental causes has been shown, the etiology of cryptorchidism remains uncertain. Cryptorchidism is an established risk factor for infertility and testicular germ cell tumors (TGCT. Experimental animal models suggest a causative role for an abnormal testicular position on the disruption of spermatogenesis however the link between cryptorchidism and TGCT is less clear. The most common type of TGCT in cryptorchid testes is seminoma, believed to be derived from pluripotent prenatal germ cells. Recent studies have shown that seminoma cells and their precursor carcinoma in situ cells express a number of spermatogonial stem cell (SSC markers suggesting that TGCTs might originate from adult stem cells. We review here the data on changes in the SSC somatic cell niche observed in cryptorchid testes of mouse models and in human patients. We propose that the misregulation of growth factors' expression may alter the balance between SSC self-renewal and differentiation and shift stem cells towards neoplastic transformation.

  18. Quiste ovárico fetal: diagnóstico prenatal y manejo quirúrgico postnatal exitoso

    Directory of Open Access Journals (Sweden)

    Alejandra Cabellos M

    2012-01-01

    Full Text Available Los quistes ováricos son el tumor abdominal mas frecuente en las recién nacidas. Presentan complicadones agudas y a largo plazo. La más frecuente es la torsión anexial que presenta dificultades diagnósticas en la etapa neonatal. El diagnóstico prenatal es fundamental para el manejo oportuno de las pacientes. Existen diferentes alternativas terapéuticas donde la cirugía mínimamente invasiva y conservadora juega un importante rol. Presentamos el caso de una recién nacida macrosómica con diagnóstico prenatal de quiste ovárico no complicado que sufrió torsión durante los primeros días de vida y se resolvió exitosamente en forma quirúrgica conservadora gracias a un manejo multidisciplinario.Ovarian cysts are the most common abdominal tumor in female newborns. They could develop acute or long term complications. The most frequent complication is adnexal torsion, which presents with diagnostic difficulties in the neonatal period. Prenatal diagnosis is essential for the prompt management of patients. There are different treatment options where conservative and minimally invasive surgery plays an important role. We report a female newborn with prenatal diagnosis of macrosomia and uncomplicated ovarian cyst, which suffered adnexal torsion during the first days of life and was successfully resolved with a conservative surgical management by a multidisciplinary staff.

  19. Quiste ovárico fetal: diagnóstico prenatal y manejo quirúrgico postnatal exitoso

    Scientific Electronic Library Online (English)

    Alejandra, Cabellos M; Isabel, Cavieres C; Pablo, Zarges T; Mario, Gajardo C; Richard, Vega D.

    Full Text Available Los quistes ováricos son el tumor abdominal mas frecuente en las recién nacidas. Presentan complicadones agudas y a largo plazo. La más frecuente es la torsión anexial que presenta dificultades diagnósticas en la etapa neonatal. El diagnóstico prenatal es fundamental para el manejo oportuno de las p [...] acientes. Existen diferentes alternativas terapéuticas donde la cirugía mínimamente invasiva y conservadora juega un importante rol. Presentamos el caso de una recién nacida macrosómica con diagnóstico prenatal de quiste ovárico no complicado que sufrió torsión durante los primeros días de vida y se resolvió exitosamente en forma quirúrgica conservadora gracias a un manejo multidisciplinario. Abstract in english Ovarian cysts are the most common abdominal tumor in female newborns. They could develop acute or long term complications. The most frequent complication is adnexal torsion, which presents with diagnostic difficulties in the neonatal period. Prenatal diagnosis is essential for the prompt management [...] of patients. There are different treatment options where conservative and minimally invasive surgery plays an important role. We report a female newborn with prenatal diagnosis of macrosomia and uncomplicated ovarian cyst, which suffered adnexal torsion during the first days of life and was successfully resolved with a conservative surgical management by a multidisciplinary staff.

  20. Abordaje endoscópico de los quistes gliales pineales sintomaticos

    Scientific Electronic Library Online (English)

    Gloria, Villalba Martínez; Luis Alberto, Caral Pons; Bartolomeu, Fiol Busquets; Neus, Fabregas Juliá; Teresa, Ribalta Ribas; Teresa, Boget Prats; Antoni, Raspall Borell; Enric, Ferrer Rodríguez.

    2009-12-01

    Full Text Available Objetivo. Los quistes gliales pineales (QGP) son infrecuentes. El manejo quirúrgico de estos quistes no está consensuado. En la literatura se recogen 18 casos tratados por vía endoscópica. El objetivo de este trabajo es contribuir con nuestra experiencia en el tratamiento endoscópico de los QGP. Mat [...] erial y método. Entre 1999 y 2004, cinco pacientes con QGP sintomáticos, con o sin hidrocefalia, se trataron mediante vintriculostomía premamilar endoscópica (VPE) y fenestración del quiste. Se utilizó un endoscopio rígido, con sistema de neuronavegación en los casos sin hidrocefalia. Resultados. En el período de seguimiento (de 6 meses a 4 años) se recoge una resolución clínica en 4 casos y una disminución del tamaño del quiste en todos los casos. Todas las VPE fueron permeables en el seguimiento. No hubo déficits clínicos permanentes en ningún caso. Discusión. No existe en la literatura un acuerdo en el mejor tratamiento quirúrgico de los QGP. A pesar de la gran aceptación de la vía endoscópica, un gran número de autores abogan por una cirugía abierta o por una cirugía extereotáxica como la mejor opción. Además, existen algunas diferencias en el manejo quirúrgico endoscópico según ofrece la literatura. Conclusión. La VPE con la fenestración del quiste es un tratamiento eficiente debido a la baja morbilidad y a la eficacia en la resolución clínica y radiológica de los QGP con o sin hidrocefalia. La cirugía abierta, especialmente con la ayuda endoscópica, podría ser un tratamietno de segunda elección, y la cirugía estereotáxica debería abandonarse en estos casos. Abstract in english Objetive. Sympotomatic glial pineal cyst (GPC) are unfrequent. Surgical management of these cysts is not consensed. In the literature there are 18 cases reported treated by endoscopic approach. The purpose of this study is to contribute with our experience to the endoscopic treatment of the GPC. Mat [...] erials and Methods. Between 1999 and 2004, five patients with GPC underwent an endoscopic third ventriculostomy (ETV) and cyst fenestration. We have used a rigid endoscope, with neuronavegation system in the cases without hydrocephalus. Results. In the follow-up period ranged from 6 months to 4 tears we have reported: clinical resolution in four cases and cyst size decrease in all cases. All the ETV have been patent. There was not perman ent morbility and not surgery related death. Discussion. An agreement doesn't exist in the literature about the better treatment of the surgery or by stereotaxy as the best treatment. There are great differences in the surgical management between the 18 endoscopic cases reported in the literature, and also in relation with our cases. Conclusion. The ETV with endoscopic cyst fenestration is an efficient treatment due to the low morbidity and the effectiveness in the treatment of the GPC with or without hydrocephalus. The open surgery (specially with the endoscope assisting microneurosurgery) wolud be a second choice technique, and the stereotactic surgery must be abandoned.

  1. Intraosseous epidermoid cysts in the distal phalanx of two dogs

    International Nuclear Information System (INIS)

    Two dogs were presented with a history of lameness associated with swelling of one of the digits. Radiographs of the affected digits revealed an irregularly mineralized, smoothly marginated proliferative bone lesion in the distal phalanx of one dog and a destructive bony lesion in the distal phalanx of the second dog. The differential diagnosis included nail bed carcinoma, malignant melanoma, osteomyelitis, and subungual keratoacanthoma. Radiographic findings and no response to medical treatment resulted in amputation and submission of the digits for a histopathologic diagnosis. Histologic examination of the distal phalanx of the digits revealed benign epidermoid cysts associated with either bony proliferation or osteolysis. Excision of the lesions was curative. This report presents the clinical, radiographic, and histopathologic findings associated with intraosseous epidermoid cysts in the distal phalanx of two dogs

  2. Sublingual Epidermoid Cyst Presenting with Distinctive Magnetic Resonance Imaging Findings

    OpenAIRE

    Yoshida, Naohiro; Kodama, Kozue; Iino, Yukiko

    2014-01-01

    A case of sublingual epidermoid cyst presenting distinctive magnetic resonance imaging (MRI) findings is described. A 39-year-old man presented to our hospital with a three months progressive left submandibular swelling, difficulty moving his tongue, and snoring. Preoperative evaluation with MRI and fine needle aspiration cytology (FNAC) revealed that the heterogeneous cystic lesion contained the squamous cells, which is compatible with ectodermal tissue. The mass was located above the mylohy...

  3. Squamous cell carcinoma arising in an intradiploic epidermoid cyst

    Energy Technology Data Exchange (ETDEWEB)

    Bretschneider, T.; Dorenbeck, U.; Strotzer, M. [Department of Radiology, University Hospital, D-93042 Regensburg (Germany); Roth, M. [Clinic for Neurosurgery, University Hospital, Regensburg (Germany); Ruemmele, P.; Buettner, R. [Department of Pathology, University Hospital, Regensburg (Germany)

    1999-08-01

    A 71-year-old woman presented with the symptoms of a posterior cranial fossa mass. CT and MRI revealed a lytic lesion in the occipital bone and a tumour infiltrating the dura mater, venous sinuses and cerebellum. Histopathology demonstrated a moderately differentiated squamous cell carcinoma arising from a primarily intradiploic epidermoid cyst. Despite surgery and radiotherapy, the tumour progressed and the patient died 1 year later. (orig.) With 4 figs., 11 refs.

  4. Spontaneous nontraumatic epidermoid cyst of the clitoris: a rare case report

    Directory of Open Access Journals (Sweden)

    Arun Nayak

    2015-12-01

    Full Text Available Epidermoid cysts are slow growing, intradermal or subcutaneous tumors with a wall composed of true epidermis. They are rarely seen in the clitoral region but when found; they are commonly seen following female genital mutilation. Spontaneous onset clitoral epidermoid cysts have been scarcely reported .We report a rare case of a large spontaneous nontraumatic epidermoid cyst of clitoris in a 22 year old nulliparous female. This presentation mimicked clitoromegaly but was diagnosed to be a large epidermoid cyst after excision. [Int J Reprod Contracept Obstet Gynecol 2015; 4(6.000: 2081-2083

  5. Sublingual epidermoid cyst presenting with distinctive magnetic resonance imaging findings.

    Science.gov (United States)

    Yoshida, Naohiro; Kodama, Kozue; Iino, Yukiko

    2014-06-18

    A case of sublingual epidermoid cyst presenting distinctive magnetic resonance imaging (MRI) findings is described. A 39-year-old man presented to our hospital with a three months progressive left submandibular swelling, difficulty moving his tongue, and snoring. Preoperative evaluation with MRI and fine needle aspiration cytology (FNAC) revealed that the heterogeneous cystic lesion contained the squamous cells, which is compatible with ectodermal tissue. The mass was located above the mylohyoid muscle and spread to the pharyngeal space. By considering the size, infection history, patient age, and location, the cyst was completely resected under general anesthesia via cervical approach without any complication. Histopathologically, the cyst wall was lined by stratified squamous epithelium with no skin appendage, suggesting an epidermoid cyst. Ultrasound (US), MRI and FNAC were very useful of the preoperative diagnosis for oral and sublingual lesion. The postoperative course was uneventful and without recurrence after 24 months. This case showed that epidermoid cysts formed the rarely heterogeneous cystic tumor and it underlined usefulness of preoperative diagnosis, such as US, MRI and FNAC for oral and sublingual tumor. PMID:25332766

  6. Sublingual epidermoid cyst presenting with distinctive magnetic resonance imaging findings

    Directory of Open Access Journals (Sweden)

    Naohiro Yoshida

    2014-08-01

    Full Text Available A case of sublingual epidermoid cyst presenting distinctive magnetic resonance imaging (MRI findings is described. A 39-year-old man presented to our hospital with a three months progressive left submandibular swelling, difficulty moving his tongue, and snoring. Preoperative evaluation with MRI and fine needle aspiration cytology (FNAC revealed that the heterogeneous cystic lesion contained the squamous cells, which is compatible with ectodermal tissue. The mass was located above the mylohyoid muscle and spread to the pharyngeal space. By considering the size, infection history, patient age, and location, the cyst was completely resected under general anesthesia via cervical approach without any complication. Histopathologically, the cyst wall was lined by stratified squamous epithelium with no skin appendage, suggesting an epidermoid cyst. Ultrasound (US, MRI and FNAC were very useful of the preoperative diagnosis for oral and sublingual lesion. The postoperative course was uneventful and without recurrence after 24 months. This case showed that epidermoid cysts formed the rarely heterogeneous cystic tumor and it underlined usefulness of preoperative diagnosis, such as US, MRI and FNAC for oral and sublingual tumor.

  7. Testicular cancer and antecedent diseases.

    OpenAIRE

    Swerdlow, A.J.; Huttly, S R; Smith, P. G.

    1987-01-01

    A case-control study of the aetiology of testicular cancer was conducted using information obtained by interview and from case-notes of 259 cases with testicular cancer and two sets of control patients -238 men with diagnoses other than testicular cancer attending the same radiotherapy centres as those attended by the cases, and 251 hospital in-patients not attending radiotherapy departments. Logistic regression analyses were performed, after stratifying by age and region of residence, to est...

  8. Toxoplasmosis testicular: un caso raro de masa testicular / Testicular toxoplasmosis: a rare case of mass testicular

    Scientific Electronic Library Online (English)

    F., Barreto; F., Hering; M.F., Dall’Oglio; D., Martini Filho; J.C., Campagnari; M., Srougi.

    2008-06-01

    Full Text Available El Toxoplasma gondii es un protozoario intracelular que infecta aves y mamíferos. La infección aguda es asintomática en pacientes inmunocompetentes. En pacientes con deficiencia inmunológica (síndrome de la inmunodeficiencia adquirida, linfomas o pacientes sometidos a terapia con corticoides para pr [...] evención de rechazo de transplante de órganos) la infección puede ser fatal. Nosotros describimos un caso poco común de toxoplasmosis testicular en paciente sometido a transplante renal hace 6 años con serología negativa para el virus VIH y sin toxoplasmosis sistémica. Abstract in english Toxoplasma gondii is an intracellular protozoan infecting birds and mammals. Acute infection is asymptomatic in immune competent people. For immune deficient patients (acquired immune deficiency syndrome, lymphoma patients or those under steroids to prevent organ transplantation rejection) infection [...] may be lethal. We describe an uncommon case of testicular toxoplasmosis in patient under steroids after organ transplantation with no positive serum test for HIV and/or systemic toxoplasmosis.

  9. Carcinoma epidermoide primitivo. Presentación de un caso: modelos de diagnóstico y evaluación / Early epidermoid carcinoma. A case presentation

    Scientific Electronic Library Online (English)

    Lidia, Torres Ajá; Julian, Viera Llanes.

    2009-12-01

    Full Text Available El carcinoma epidermoide primitivo es considerado el tumor más raro de la mama, con una incidencia que representa solo del 0,04 al 0,075 % de todos los tumores malignos de mama. Es una variedad de carcinoma metaplásico constituido por células pavimentosas queratinizantes, con presencia inconstante d [...] e elementos fusocelulares sarcomatoides, estos alcanzan grandes volúmenes y se presentan frecuentemente como tumoraciones quísticas que pueden confundirse con un absceso mamario. El caso que se presenta es una paciente femenina de 41 años de edad, de color de piel blanca, residente en el municipio de Cienfuegos que acudió a la consulta de Mastología de la provincia por presentar una tumoración de 5 cms. en el cuadrante superior externo de la mama derecha, de dos meses de evolución. Se realizó exèresis de la tumoración y se recibió informe de la biopsia con el resultado de carcinoma epidermoide poco diferenciado. Actualmente la paciente es seguida por consulta y está libre de metástasis. Por lo inusual del caso se decide su publicación. Abstract in english The early epidermoid carcinoma is considered the strangest breast tumor with an incidence that only represents from 0,04 to 0,075 % out of all malignant tumors of the breast. It is a variety of the metaplastic carcinoma constituted by pavement keratinizing cells with an inconstant presence of fusoce [...] llular sarcomatoid elements, that reach great volume and frequently present as cystic tumours that may be confused with a breast abscess. This is the case of a 41 year-old white female from Cienfuegos municipality, Cuba, who presented to the provincial Mastology consultation because of a two month follow up of a 5 cm tumor in the right outer upper quadrant of her breast. Surgical removal of the tumor was performed and the result of the biopsy revealed a little differentiated epidermoid carcinoma. At present the patient has no metastasis and receives treatment at the outpatient. Its unusual presentation has led this case to be published.

  10. Encefalitis límbica paraneoplásica y carcinoma epidermoide del seno piriforme / Paraneoplastic limbic encephalitis and epidermoid carcinoma of the pyriform sinus

    Scientific Electronic Library Online (English)

    M. A., Sobas; M. A., Galiano Leis; R. de la, Fuente Cid; I., Pereiro Zabala.

    2006-07-01

    Full Text Available La encefalitis límbica paraneoplásica es un síndrome que se caracteriza clínicamente por alteraciones de comportamiento, trastornos de memoria reciente y crisis epilépticas. Presentamos el caso clínico de un varón de 62 años, ex-fumador, que ingresa en UCI por un cuadro de crisis convulsivas, presen [...] tando anteriormente cambios en el carácter. Los estudios practicados resultaron negativos a excepción de LCR con hiperproteinorraquia y RNM que mostraba lesiones en el lóbulo temporal . Una vez descartadas otras posibles etiologías, iniciamos despistaje de neoplasia oculta. No se evidenció tumor en las pruebas de imagen habituales. Los anticuerpos anti-Hu resultaron negativos. Se realizó tomografía de emisión de positrones (TEP) de cuerpo entero que reveló un foco de hipercaptación a nivel faringolaríngeo. La biopsia fue diagnóstica de carcinoma epidermoide del seno piriforme. En nuestro conocimiento es el primer caso de ELP asociada a carcinoma epidermoide del seno piriforme. Abstract in english Paraneoplastic limbic encephalitis is a syndrome characterised by behaviour changes, short-term memory loss and seizures. We report on a case of a 62-year-old man, ex-smoker who was admitted to the Intensive Care Unit with seizures, and who had previously experienced behaviour changes. Tests reveale [...] d nothing notable, except for the CSF examination which revealed elevated protein and MRI findings indicating temporal lobe abnormalities. Once other diagnoses had been ruled out, neoplasm screening was initiated. Conventional imaging failed to identify the tumour. Antineuronal anti-Hu antibodies were negative. Finally, fluorodeoxyglucose (FDG) whole body -PET imaging was carried out revealing a pathologically increased glucose metabolism at the pharynx-larynx level. The biopsy showed an epidermoid carcinoma of the pyriform sinus. To the best of our knowledge, this is the first reported case of an epidermoid carcinoma of the pyriform sinus associated with paraneoplastic limbic encephalitis.

  11. Cáncer de quiste en conducto tirogloso / Thyroglossal duct cyst cancer

    Scientific Electronic Library Online (English)

    Manuel Francisco, Jiménez-Navarrete; Laura, Ulate-Oviedo; María, Aguilar-Aráuz; Gerardo, Sáenz-Batalla.

    2013-12-01

    Full Text Available El quiste del conducto tirogloso es una de las anomalías del desarrollo que se presentan más frecuentemente en el cuello. La presencia en este de carcinoma aislado o concomitante con cáncer en tiroides, es muy infrecuente. Se expone aquí el caso de una paciente joven que se presentó con esta entidad [...] . Se describe su presentación y manejo. Actualmente sigue su control en el Servicio de Endocrinología del Hospital San Vicente de Paúl, Heredia, Costa Rica. Abstract in english Thyroglossal duct cyst cancer is one of the developmental anomalies that not occur frequently in the neck. The presence of isolated or concomitant thyroid cancer is unusual. We present the case of a young female patient with this condition. Presentation and management are described. The Endocrinolog [...] y Service of the San Vicente de Paul Hospital is presently following her case.

  12. Quistes solitarios no parasitarios del hígado: Presentación de 9 casos

    Scientific Electronic Library Online (English)

    Eddy, Sierra Enrique; Javier, Vázquez Roque; Gilberto, Martínez Ramos.

    1999-08-01

    Full Text Available Se estudian 9 pacientes intervenidos quirúrgicamente en los hospitales Clinicoquirúrgico Provincial Docente y Militar "Comandante Manuel Fajardo", ambos de Santa Clara, por presentar quiste solitario no parasitario del hígado. La edad de presentación predominante fue después de los 60 años, y el sex [...] o femenino el más afectado. Siete de los quistes se localizaron en el lóbulo derecho, y 2 en el lóbulo izquierdo del hígado. El dolor abdominal y la tumoración palpable fueron los aspectos más llamativos en el cuadro clínico y el examen físico. La laparoscopia, el ultrasonido abdominal y la tomografía axial computadorizada (TAC) constituyeron los exámenes más útiles para el diagnóstico. La cistoyeyunostomía fue la técnica quirúrgica más utilizada. En 3 pacientes se presentaron complicaciones, para el 33,3 % y 1 falleció, lo que representa el 11,1 % de mortalidad Abstract in english 9 patients that were operated on at the Provincial Clinical and Surgical Teaching Hospital and at the "Comandante Manuel Fajardo" Military Hospital, both in Santa Clara, for presenting solitary nonparasitic hepatic cyst were studied. It appeared mainly in patients over 60, and females were the most [...] affected. 7 of the cysts were located in the right lobule and 2 in the left lobule of the liver. Abdominal pain and palpable tumors were the most important aspects in the clinical picture and in the physical examination. Laparoscopy, abdominal ultrasound and CAT were the most useful tests for the diagnosis. Cystojejunostomy was the most used surgical technique. 3 patients had complications, accounting for 33.3 %, and 1 died, which represents 11.1 % of mortality

  13. Asymptomatic intradiploic epidermoid cyst eroding frontal bone in a patient with craniosynostosis.

    Science.gov (United States)

    Yildiz, Kemalettin; Sagir, Haci Ömer; Tosuner, Zeynep; Canter, Halil Ibrahim; Guneren, Ethem

    2015-01-01

    Epidermoid cyst located in cranium is uncommon and usually diagnosed with a growing mass leading to symptoms. Asymptomatic intradiploic epidermoid cyst has not been reported yet. In this study, incidental diagnosis of asymptomatic cyst and potential impact of that cyst on surgical planning of a patient with craniosynostosis are presented. PMID:25569418

  14. Cranial cystic epidermoid: report of two cases and review of the literature

    International Nuclear Information System (INIS)

    Intercranial epidermoid tumours are benign lesions of congenital origin that are potentially curable. Although computerized axial tomography (CT) and magnetic resonance imaging (MRI) are usually diagnostic, a few atypical features sometimes make pre-operative diagnosis difficult. Two cases of cystic epidermoids with peripheral ring enhancement are reported. Relevant literature has been reviewed. 15 refs., 2 figs

  15. Carcinoma epidermoide de canal anal estádio IV: complicações clínicas de doença avançada Epidermoid carcinoma of anal canal stage IV: clinical complications of advanced disease

    OpenAIRE

    Fernanda Bellotti Formiga; Alessandra Vicentini Credidio; Daltro Lemos Rosa; José César Assef; Chia Bin Fang; Peretz Capelhuchnik; Wilmar Artur Klug

    2010-01-01

    O carcinoma anal é uma entidade rara que representa 4% dos tumores malignos da região anorretal, dentro os quais o carcinoma epidermoide constitui o tipo histológico mais comum. É relatado o caso de um paciente masculino, 54 anos, com carcinoma epidermoide de canal anal localmente avançado e com metástases ósseas no diagnóstico, feito após complicação infecciosa local com repercussão sistêmica. Descrevemos a evolução do paciente após o diagnóstico da neoplasia e as dificuldades de manejo clín...

  16. Leech therapy for epidermoid cysts and review of the literature

    OpenAIRE

    Abbas Rasi; Alireza Faghihi; Mirhadi Aziz Jalali; Abbas Zamanian; Gholamhossein Ghaffarpour

    2014-01-01

    Hirudo medicinalis sucks blood directly through the external mammalian skin. We recently observed a healthy 64-year-old Iranian man, who presented with numerous asymptomatic multilobular oval-to-round well-defined 0.5 to 1.5 cm cystic lesions with central umbilication (central black eschar) over the upper portion of his chest. We made the diagnosis of epidermoid cyst, giant comedone and leech bite on the basis of the constellation of clinical features. The patient was treated with oral ciprof...

  17. Factors Predicting Testicular Atrophy after Testicular Salvage following Torsion.

    Science.gov (United States)

    Lian, Bertrand S Y; Ong, Caroline C P; Chiang, Li Wei; Rai, Rambha; Nah, Shireen Anne

    2016-02-01

    Introduction?Testicular atrophy (TA) is a significant complication in patients who undergo salvage procedures for testicular torsion. Studies on outcome focus on factors predicting testicular viability during scrotal exploration but few assess factors predicting TA in patients who undergo salvage procedures. We assess the incidence of TA after salvage and identify associated factors. Materials and Methods?With ethical approval, we reviewed patients who underwent salvage for testicular torsion in our institution from 2001 to 2013. Data was collected on patient demographics, duration of pain, sonographic findings, postoperative complications, and follow-up assessment of TA (defined as difference in testicular volume?>?50% compared with the contralateral testis, based on measurement by Prader orchidometer or by ultrasound). We excluded patients with torted undescended testis, those under 1?month, and those with follow-up??1 day (p?=?0.004) and heterogeneous echogenicity on ultrasound (p?=?0.001). Sonographic evidence of reduced vascularity was not predictive. Of 11 that had pain?>?1 day, 10 (91%) had TA. No testes survived when pain ? 3 days. Conclusion?Half of patients with testicular torsion undergoing salvage surgery will develop testicular atrophy, even when intraoperatively assessed as viable, and should be counseled accordingly. Duration of pain?>?1 day and sonographic heterogeneous echogenicity are predictive. Salvage rates are dismal when duration of symptoms exceeds 1 day. PMID:26509312

  18. Studies of testicular function after treatment for testicular tumor, 1

    International Nuclear Information System (INIS)

    Recently, the treatment for testicular tumor has improved. Preservation of testicular function in the treatment of testicular tumor is important, because the majority of the patients are young. We investigated the testicular function of patients with testicular tumor before, during and after treatment. As a part of this study, the fertility of patients with testicular tumor before and after treatment was evaluated. 1. Fourteen of 78 married patients (18 %) showed sterility for two or more years before treatment. 2. When semen was examined in 31 patients before treatment, only seven patients (23 %) showed normal sperm counts of more than 40 x 106/ml, and 19 (61.3 %) showed oligospermia or azoospermia with sperm counts of less than 10 x 106/ml. 3. Of 20 patients who underwent retroperitoneal lymphnode dissection, 15 developed ejaculation deficiency. Four other patients also developed ejaculation deficiency but recovered, and three of them rendered their wives pregnant. 4. Of 23 patients given radiotherapy, nine produced children both before and after treatment, nine produced children before treatment but showed sterility after treatment, and five showed sterility both before and after treatment. 5. Examination of semen was performed in 17 patients given radiotherapy and in five given chemotherapy. Many patients developed oligospermia or azoospermia after the treatments, but revealed a tendency to recover with time. Based on the results mentioned above, it is inferred that the ability to produce sperm in patients with testicular tumor after treatment decreases but the decrease tends to recover to normal with time. (author)

  19. Quiste óseo simple de cóndilo mandibular / Simple bone cyst of the mandibular condyle

    Scientific Electronic Library Online (English)

    Julio, Cifuentes; Ariel, Barrera; Daniel, Jerez; Stephanie, Bohmann.

    2015-03-01

    Full Text Available El quiste óseo simple (QOS) es una entidad descrita por primera vez por Lucas en 1929. En 1946, Rushton describió las paredes internas del quiste que consistían en tejido óseo sin contenido patológico o químico. Esta entidad intraósea también es conocida con múltiples sinónimos como quiste óseo soli [...] tario, quiste óseo traumático, quiste óseo hemorrágico, quiste unicameral, cavidad ósea idiopática y cavidad o quiste óseo progresivo. Cuando afecta a los maxilares suelen ser asintomáticos, siendo su diagnóstico habitualmente un hallazgo radiológico. Las áreas comúnmente afectadas son entre los caninos inferiores y la región de los terceros molares y, en segundo lugar, la sínfisis mandibular. Los QOS de cóndilo son raros, habiéndose referido previamente 15 casos en la literatura. En el caso referido se describirá el tratamiento y se hará una revisión de la enfermedad. Abstract in english Simple bonecysts (SBC) have been a recognized entity since 1929, when they were first described by Lucas. In 1946, Rushton described the inner walls of the cyst, consisting of bone and no pathological or chemical content. This intraosseous entity, is also known by a variety of synonyms including sol [...] itary bone cyst, traumatic bone cyst, hemorrhagic bone cyst, unicameral cyst, idiopathic bone cavity and progressive bone cyst or cavity. There are few clinical features within the jaws, and the diagnosis is made mainly from radiographical findings. The most frequently affected sites are the region between inferior canines and third molars, and secondly in the mandibular symphysis. SBC of the condyle are rare, and there are approximately 15 cases in the current literature. Treatment of the case will be described, and a literature review of the disease and its management will be presented.

  20. Testicular cytology in azoospermia

    Directory of Open Access Journals (Sweden)

    Usha Prasad

    2015-06-01

    Results: The commonest group with infertility were in the age group 21-30 years. The testicular size was normal in 87.17% of subjects and 12.82% had small testis. Out of 39 subjects with azoospermia 38.46% subjects had varicocele. Varicocele was commonly associated with duct obstruction. The commonest causes observed in cases with azoospermia were; hypospermatogenesis with maturation arrest (4/39,10.25%, duct obstruction (12/39,30.76%, maturation arrest (7/39,17.94%, testicular atrophy (10/39,25.64% and sertoli cell only syndrome (2/39,5.12%. In the present study diagnostic accuracy was 89.18%. Conclusions: Fine needle aspiration cytology is as informative as biopsy and can be done as a routine procedure. It helps us in ruling out obstructive and non-obstructive causes for azoospermia. In cases where FNAC shows normal spermatogenesis with azoospermia, biopsy and Doppler study is indicated to rule out duct obstruction which can be corrected surgically. It is a simple and cost effective. [Int J Reprod Contracept Obstet Gynecol 2015; 4(3.000: 647-652

  1. TESTICULAR FEMINISING SYNDROME

    Directory of Open Access Journals (Sweden)

    Vijay Kumar

    2014-03-01

    Full Text Available Testicular feminization syndrome is a form of pseudohermaphroditism where phenotypic female has male gonads and is genotypically male. Androgen insensitivity syndrome (AIS, also known as testicular feminization, encompasses a wide range of phenotypes that are caused by numerous different mutations in the androgen receptor gene. AIS is an X-linked recessive disorder that is classified as complete, partial based on the phenotypic presentation. The clinical findings include a female type of external genitalia, 46-XY karyotype, absence of Mullerian structures, presence of Wolffian structures to various degrees, and normal to high testosterone and gonadotropin levels. The syndrome is illustrated by a 24-year-old phenotypic female who presented with a primary amenorrhea, female-type external genitalia, an absent uterus and ovaries, and bilateral testes at the level of the internal inguinal ring. Management includes counseling, gonadectomy to prevent primary malignancy in undescended gonad, and hormone replacement. The karyotyping of family members is advocated because of known familial tendencies.

  2. Unusual Presentation of a Left Testicular Carcinoid

    OpenAIRE

    Palla, Amruth R.; Hogan, Thomas; Singh, Sindhu

    2012-01-01

    Testicular carcinoid generally presents either with a palpable (painful or painless) or rarely a nonpalpable mass (when it is diagnosed incidentally on scrotal imaging) of the involved testis. An ipsilateral testicular carcinoid presenting exclusively with contralateral testicular symptoms has never been described in the literature to date. We report a case of nonpalpable left testicular carcinoid diagnosed incidentally on a sonogram done for right testicular pain and swelling, with conspicuo...

  3. Epidermoid gastric cancer review literature a case study

    International Nuclear Information System (INIS)

    Full text: introduction. epidermoid epidemiologic ally gastric cancer etiology is extremely uncommon forming a 0.04 to 0.07% of cases. target. reviewing the literature from a clinical case of a female patient 60 years epidermoid carrier loco regionally advanced gastric cancer. methodology and methods. analyze the case of gastric cancer squamous which TB diagnosed n2 m0 be a eiiic. results. the case was presented as an atypical dyspepsia was diagnosed with cancer gastric squamous after taking multiple biopsies. diagnosis is confirmed and the checked laparoscopically resectable liver infiltration, commitment vascular and pancreatic seen by ct scan. it was decided to establish treatment palliative chemotherapy based on docetaxel, 5-fluorouracil and cisplatin that fails to receive and who dies of massive haematemesis. conclusions. it is well established the pathogenesis of this disease. in series reported we found a higher incidence in males, with a median age presentation at age 64. the most common is the fun dus and diagnosis in advanced stages is most prevalent. being a rare histological subtype as there is no evidence to support a massed different therapeutic adenocarcinoma

  4. Quistes y fístulas del conducto tirogloso: Nuestra experiencia

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    Manuel Estrada Sarmiento

    1996-12-01

    Full Text Available Se realiza una investigación observacional, retrospectiva y descriptiva de 65 pacientes con diagnóstico clínico e histológico de quistes y/o fístula del conducto tirogloso, con el objetivo de conocer su comportamiento en nuestro medio durante el período 1963-1993. De los 65 pacientes 43 eran masculinos (66,1 % y 22 femeninos. El 20 % con una edad inferior a los 10 años. Nueve pacientes (13,8 % tenían antecedentes de cirugía previa. Se manifestaron como una tumoración cervical en 54 pacientes y en 6 como una fístula. La técnica quirúrgica de Sistrunk se empleó en 62 pacientes (95,4 % en los restantes la exéresis simple del quiste. La mortalidad operatoria fue nula. Tres pacientes (4,6 % presentaron sepsis de la herida. El seguimiento mínimo de los pacientes fue de un año. Dos pacientes mostraron recidivas y fueron reintervenidos a los 10 meses. Esta entidad es relativamente frecuente con predominio en las primeras décadas de la vida. Una terapéutica adecuada conlleva a la resolución de ésta con mortalidad nulaA observational retrospective, and descriptive investigation of 65 patients with clinical and histology-cal diagnosis of cysts and/or fistulas of the thyroglossal duct was carried out to know their behaviour in our enviroment during the period 1983-1993. 43 of the 65 patients were males (66,1 % and 22 females. 20 % of them were under 10 years old. Nine patients (13,8 % had undergone surgery before. Cervical tumour was found in 54 patients and fistula in 6. The Sistrunk's surgical technique was used in 62 patients (95,4 %, where as in the rest it was used the simple exeresis of the cyst. Operative mortality was null. Three patients (4,6 % presented incision sepsis. The minimun follow-up lasted one year. Two patients relapsed and were operated on again 10 months later. This affection is relatively frequent with predominance in the first decades of life. An adequate therapeutics leads to the resolution of it with no mortality

  5. Quistes y fístulas del conducto tirogloso: Nuestra experiencia

    Scientific Electronic Library Online (English)

    Manuel, Estrada Sarmiento.

    1996-12-01

    Full Text Available Se realiza una investigación observacional, retrospectiva y descriptiva de 65 pacientes con diagnóstico clínico e histológico de quistes y/o fístula del conducto tirogloso, con el objetivo de conocer su comportamiento en nuestro medio durante el período 1963-1993. De los 65 pacientes 43 eran masculi [...] nos (66,1 %) y 22 femeninos. El 20 % con una edad inferior a los 10 años. Nueve pacientes (13,8 %) tenían antecedentes de cirugía previa. Se manifestaron como una tumoración cervical en 54 pacientes y en 6 como una fístula. La técnica quirúrgica de Sistrunk se empleó en 62 pacientes (95,4 %) en los restantes la exéresis simple del quiste. La mortalidad operatoria fue nula. Tres pacientes (4,6 %) presentaron sepsis de la herida. El seguimiento mínimo de los pacientes fue de un año. Dos pacientes mostraron recidivas y fueron reintervenidos a los 10 meses. Esta entidad es relativamente frecuente con predominio en las primeras décadas de la vida. Una terapéutica adecuada conlleva a la resolución de ésta con mortalidad nula Abstract in english A observational retrospective, and descriptive investigation of 65 patients with clinical and histology-cal diagnosis of cysts and/or fistulas of the thyroglossal duct was carried out to know their behaviour in our enviroment during the period 1983-1993. 43 of the 65 patients were males (66,1 %) and [...] 22 females. 20 % of them were under 10 years old. Nine patients (13,8 %) had undergone surgery before. Cervical tumour was found in 54 patients and fistula in 6. The Sistrunk's surgical technique was used in 62 patients (95,4 %), where as in the rest it was used the simple exeresis of the cyst. Operative mortality was null. Three patients (4,6 %) presented incision sepsis. The minimun follow-up lasted one year. Two patients relapsed and were operated on again 10 months later. This affection is relatively frequent with predominance in the first decades of life. An adequate therapeutics leads to the resolution of it with no mortality

  6. Quiste de conducto de Skene en niñas: A propósito de 2 casos clínicos

    Directory of Open Access Journals (Sweden)

    Alberto Miño Barrera

    2014-10-01

    Full Text Available Introducción: El quiste del conducto de Skene, se describe dentro de los quistes parauretrales, siendo una rara anomalía congénita descrita en neonatos de sexo femenino, que se puede presentar en el transcurso de la vida. La incidencia varía de 1 cada 2.000-3.000 recién nacidos vivos femeninos. Objetivo: Dar a conocer las características y formas de presentación del quiste del conducto de Skene en distintas etapas del desarrollo del niño para su sospecha y diagnóstico oportuno. Casos clínicos: Se presenta una recién nacida con una lesión tumoral amarillenta, adyacente al meato uretral, no dolorosa, que drena espontáneamente y un segundo caso de una adolescente que consulto por leucorrea de un año de evolución, con una lesión parauretral de tres centímetros de diámetro entre labios menores, que requirió tratamiento quirúrgico y estudio de la masa parauretral. Conclusiones: Basado en la revisión de la literatura, concluimos que la frecuencia de los quistes de conducto de Skene es más alta que el número de casos informados. La extirpación, marsupialización, la punción y aspiración del quiste son todos métodos eficaces de tratamiento. El drenaje espontáneo también es una conducta apropiada en ciertos casos. Se sugiere utilizar la técnica menos agresiva acorde a cada caso.

  7. Hematospermia y quiste del conducto mülleriano / Hematospermia and mullerian duct cyst

    Scientific Electronic Library Online (English)

    Nuria, Rodríguez García; Inmaculada, Fernández González; Carlos, Pascual Mateo; Gino, Espinales Castro; Ana Mª, García Tello; Antonio, Berenguer Sánchez.

    2005-12-01

    Full Text Available OBJETIVO: presentación de un caso de quiste de utrículo tratado endoscópicamente. MÉTODO: describimos el caso de un varón de mediana edad que consulta por hematospermia monosintomática de larga evolución. Al tacto rectal presentaba una próstata adenomatosa no sospechosa. Se practicó ecografía transr [...] ectal que revela quiste de utrículo complicado. RESULTADOS: Se realizó marsupialización endoscópica del quiste, consiguiendo remisión total de la hematospermia. CONCLUSIONES: Se debe realizar ecografía transrectal a todos los pacientes que consultan por hematospermia de larga evolución, indicando la marsupialización endoscópica del quiste del conducto mülleriano en aquellos pacientes sintomáticos y con quistes complejos observados en la exploración ecográfica, obteniendo un importante porcentaje de cura o mejoría en este grupo de pacientes sin inducir ningún efecto colateral secundario. Abstract in english OBJECTIVES: To report one case of utriculum cyst treated endoscopically. METHODS: We describe the case of a mid-age male patient consulting for long-term monosymptomatic hemospermia. Rectal digital examination revealed a non suspicious adenomatous prostate. Transrectal ultrasound showed a complicate [...] d utriculum cyst. RESULTS: Endoscopical marsupialization of the cyst was performed with complete remission of hemospermia. CONCLUSIONS: Transrectal ultrasound should be performed in all patients presenting with long-term hemospermia. Endoscopical marsupialization of the mullerian duct cyst is indicated in symptomatic patients or those with complex cysts on ultrasound, offering a high cure/improvement rate in this group of patients without secondary effects.

  8. Quiste broncogénico cervical: Reporte de un caso / Cervical bronchogenic cyst: Report of one case

    Scientific Electronic Library Online (English)

    JUAN ANTONIO, PÉREZ P; MAURICIO, GABRIELLI N; ORLANDO, FELMER E; CRISTIÁN, CARRASCO L.

    2008-02-01

    Full Text Available Los quistes broncogénicos son malformaciones congénitas del árbol traqueobronquial que se ubican preferentemente en pulmones y mediastino, siendo excepcional su aparición en el cuello. Esta situación conlleva que ante una masa cervical de esta naturaleza se postulen diferentes diagnósticos clínicos [...] de lesiones cervicales que son más corrientes, tales como quiste tiroideo, tirogloso, branquial y tímico, entre otros. La imagenología informa sobre el carácter quístico de la lesión pero no proporciona hallazgos específicos. Durante la intervención quirúrgica tampoco es posible establecer el diagnóstico, puesto que la masa simula los quistes cervicales congénitos más frecuentes. El diagnóstico definitivo se establece mediante la biopsia al constatar en la pared del quiste epitelio respiratorio. Comunicamos el caso de una mujer que presentó un quiste broncogénico de ubicación cervical y discutimos algunos aspectos de esta interesante condición Abstract in english Bronchogenic cysts are congenital malformations of the tracheobronchial tree that are mainly located in the lungs and mediastinum. Occasionally, they can appear in the neck, generating a cervical mass. Pathology gives the definitive diagnosis. We report a 19 years old female that consulted for an as [...] ymptomatic central cervical mass. On examination, a 4 cm diameter painless suprasternal nodule was palpated. Cervical ultrasound and CAT scan showed a cystic lesion. The cyst was completely excised surgically and the pathological report disclosed a bronchogenic cyst

  9. Quiste broncogénico cervical: Reporte de un caso Cervical bronchogenic cyst: Report of one case

    Directory of Open Access Journals (Sweden)

    JUAN ANTONIO PÉREZ P

    2008-02-01

    Full Text Available Los quistes broncogénicos son malformaciones congénitas del árbol traqueobronquial que se ubican preferentemente en pulmones y mediastino, siendo excepcional su aparición en el cuello. Esta situación conlleva que ante una masa cervical de esta naturaleza se postulen diferentes diagnósticos clínicos de lesiones cervicales que son más corrientes, tales como quiste tiroideo, tirogloso, branquial y tímico, entre otros. La imagenología informa sobre el carácter quístico de la lesión pero no proporciona hallazgos específicos. Durante la intervención quirúrgica tampoco es posible establecer el diagnóstico, puesto que la masa simula los quistes cervicales congénitos más frecuentes. El diagnóstico definitivo se establece mediante la biopsia al constatar en la pared del quiste epitelio respiratorio. Comunicamos el caso de una mujer que presentó un quiste broncogénico de ubicación cervical y discutimos algunos aspectos de esta interesante condiciónBronchogenic cysts are congenital malformations of the tracheobronchial tree that are mainly located in the lungs and mediastinum. Occasionally, they can appear in the neck, generating a cervical mass. Pathology gives the definitive diagnosis. We report a 19 years old female that consulted for an asymptomatic central cervical mass. On examination, a 4 cm diameter painless suprasternal nodule was palpated. Cervical ultrasound and CAT scan showed a cystic lesion. The cyst was completely excised surgically and the pathological report disclosed a bronchogenic cyst

  10. Epidermoid cyst of the floor of the mouth. A case report and literature review

    Directory of Open Access Journals (Sweden)

    Rojas-Madrigal A

    2012-02-01

    Full Text Available Dermoid and epidermoid cysts are cystic benign, slightly common malformations that may be found in the area of head and neck between 1.6 and 7 %, representing less than 0.01 % of all the cysts of the oral cavity. This pathology is important of the knowledge of the professional in dentistry and medicine to be able to do the early diagnose and the respective treatment. The purpose of this study is the review of the relevant literature of the dermoid and epidermoid cysts and the presentation of a case of epidermoid cyst in floor of mouth in a patient of 13 years and 5 months of age.

  11. Congenital epidermoid cyst results in muscle fusion defect in the upper lip.

    Science.gov (United States)

    Dogan, Fatih; Bucak, Ibrahim Hakan

    2014-01-01

    Epidermoid cysts are rarely detected malformations in the oral cavity. Their development sites are the sublingual, submaxillary, and submandibular spaces. In this paper, we report a three-month-old infant who was admitted to our hospital due upper lip swelling. Magnetic resonance imaging showed that she had a two-centimeter cystic lesion and fusion defects of orbicularis oris muscle. The cyst was surgically removed and histopathological diagnosis was "epidermoid cyst." In recent literature, we could not find reports related to orbicularis oris muscle fusion defects because of epidermoid cyst. PMID:25628908

  12. Quiste hidatídico hepático a propósito de un caso

    Scientific Electronic Library Online (English)

    Clavo, María Luisa; Lloeznaly, Ochoa; Julio, Vargas; Belkisyolé, de Noya; Carmen, Zuramay.

    2007-09-01

    Full Text Available Se reporta el caso de paciente femenina de 51 años, con antecedente de contacto con animales domésticos, a la cual se le realizó diagnóstico de quiste hidatídico hepático, en base a estudios de imagen y paraclínicos compatibles por patrón ecográfico, con gran Lesión de Ocupación de Espacio (LOE) quí [...] stica, multivesicular, de aspecto septado, en lóbulo hepático derecho, eosinofilia moderada y discreta elevación del perfil bioquímico hepático, con Elisa (IgG) para hidatidosis positivo, que manifestó buena respuesta a terapia farmacológica única con benzimidazoles (Albendazol) vía oral, con disminución progresiva de la lesión hasta su total desaparición, sin requerir tratamiento quirúrgico, en seguimiento actual de 13 meses. Se revisa la literatura de la enfermedad y manejo terapéutico de la misma. Abstract in english We report the case of a 51 years old female patient, with a history of contact with domestic animals, to whom we diagnosed a Hepatic Hydatid Cyst, on the grounds of image studies and laboratory tests compatible with a spaceoccupying lesion, multivesicular cysts, in the right hepatic lobe; moderate e [...] osinophilia, and a discreet elevation of the hepatic biochemical profile, with Elisa (IgG) positive for Hydatid Cyst disease. She showed a good response to single therapy with benzimidazole (Albendazole), given orally, with a progressive diminution of the lesion until its total disappearance, without requiring surgical treatment, at follow up for 13 months. We review the literature relative to this disease and its therapeutic options.

  13. QUISTE PARAOVARICO COMPLICADO: CAUSA RARA DE DOLOR ABDOMINAL

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    Ester Ureta H

    2007-01-01

    Full Text Available Se presentan los hallazgos ultrasonográficos y laparoscópicos en un caso de quiste paraovárico torcido correspondiente a una hidátide de Morgagni sin compromiso de la trompa ni del ovario. La paciente de 11 años consultó, al servicio de urgencia por un dolor abdominal agudo que hizo plantear clínicamente la existencia de una apendicitis aguda. La identificación de un apéndice y ovarios normales, junto al hallazgo de una estructura quística compleja próxima al ovario llevaron a la cirugía laparoscópica que identificó la hidátide torcida a derecha y una estructura quística similar no torcida a izquierda. Se discute esta patología como una eventual y rara causa de dolor abdominal agudo en el sexo femenino: We report the ultrasonographic and laparoscopic findings in a case of twisted parovarian cyst related with a Morgagni hydatid, without involving of the tube and ovary. The 11 years old patient consulted for an acute abdominal pain that made suspect the clinical existence of acute appendicitis. The identification of normal appendix and ovaries, and the finding of a complex cyst structure close to the ovary, led to the laparoscopic surgery, that identified a twisted hydatid at the right side and a non twisted cystic structure at the left side. We discuss this pathology as an eventual and rare cause of acute abdominal pain in females

  14. Quiste de Baker en el curso de la artritis reumatoidea

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    José Pedro Martínez Larrarte

    2000-03-01

    Full Text Available Se presentó un caso con diagnóstico de artritis reumatoidea seropositiva, de un año de evolución, que llevó tratamiento con aines y metotrexate, a pesar de lo cual, mantuvo actividad inflamatoria articular en el nivel de carpos y rodillas, que desarrolló un aumento de volumen de la región posterior de ambas piernas, con dolor espontáneo y signo de Homans positivo. Se valoró la posibilidad inicial de una tromboflebitis de la región poplítea y se llegó a la conclusión que se trataba de un quiste de Baker.A case with diagnosis of seropostive rheumatoid arthritis and a year of evolution was presented. The patients was treated with non-steroidal anti-inflammatories and methotrexate. In spite of this, the inflammatory articular activity was maintained at the level of the carpus and knees and there was a volume increase in the posterior region of both legs, with spontaneous pain and positive Homan´s sign. At first, it was evaluated the possibility of a thrombophlebitis of the popliteal region, but, finally, it was considered as a Baker´s cyst.

  15. MRI of testicular disease

    International Nuclear Information System (INIS)

    The value of T1-weighted sequences after intravenous administration of Gd-DTPA and of T2-weighted sequences was compared in 43 patients suspected of having scrotal abnormalities. T2-weighted sequences gave better demonstration of the tunica albuginea and better contrast between tumor and parenchyma. The two techniques were equally sensitive for demonstrating testicular tumors but orchitis was better demonstrated on the contrast enhanced sequences. Motion artifacts were less marked in the T1-weighted sequences with contrast enhancement. In selected cases, contrast enhancement may be a valuable addition to native protocols. Our experience has indicated that MRI provides specific findings in cases of orchitis which are clinically atypical; this facilitates the decision to conservative treatment and prevents unnecessary exploration of the testes. (orig.)

  16. Testicular degeneration in Huntington disease.

    Science.gov (United States)

    Van Raamsdonk, Jeremy M; Murphy, Zoe; Selva, David M; Hamidizadeh, Reza; Pearson, Jacqueline; Petersén, Asa; Björkqvist, Maria; Muir, Cameron; Mackenzie, Ian R; Hammond, Geoffrey L; Vogl, A Wayne; Hayden, Michael R; Leavitt, Blair R

    2007-06-01

    Huntington disease (HD) is an adult onset, neurodegenerative disorder that results from CAG expansion in the HD gene. Recent work has demonstrated testicular degeneration in mouse models of HD and alterations in the hypothalamic-pituitary-gonadal (HPG) axis in HD patients. Here, we show that HD patients have specific testicular pathology with reduced numbers of germ cells and abnormal seminiferous tubule morphology. In the YAC128 mouse model, testicular degeneration develops prior to 12 months of age, but at 12 months, there is no evidence for decreased testosterone levels or loss of GnRH neurons in the hypothalamus. This suggests that testicular pathology results from a direct toxic effect of mutant huntingtin in the testis and is supported by the fact that huntingtin is highly expressed in the affected cell populations in the testis. Understanding the pathogenesis of HD in the testis may reveal common critical pathways which lead to degeneration in both the brain and testis. PMID:17433700

  17. Testicular metastasis of prostatic cancer.

    Science.gov (United States)

    Smaali, Chemsedine; Gobet, Francoise; Dugardin, Fabrice; Pfister, Christian

    2010-02-01

    Secondary testicular tumors are rare, we report a case of a solitary testicular metastasis of prostate cancer in 58-year-old man treated using hormonal therapy associated with radiotherapy. Ultrasound is the imaging modality of choice, but metastasis might be difficult to differentiate from primary tumors. The diagnosis confirmed by histologic examination includes routine microscopic and immunohistochemical findings, and therefore systemic treatment was required. PMID:19913885

  18. Testicular microlithiasis and cryptorchidism a case report

    Directory of Open Access Journals (Sweden)

    Z. Miabi

    2006-01-01

    Full Text Available Testicular microlithiasis (TM is an uncommon condition with reported prevalence of 0.6% in patients referred for scrotal ultrasound. Testicular microlithiasis was first reported by Priebe and Garret in 1970 and defined as multiple tiny calcification throughout the testis. The condition appears as characterstic small nonshadowing hyperechoic stippling foci in testicular parenchyma. Several associations have been reported with testicular microlithiasis.Considrable accrued evidence points to an association between testicular microlithiasis, intra tubular germ cell neoplasia and testicular tumor. This topic is of considerable attention to researchers. We recommend annual ultrasonic follow up and patient education about self- examination and bio-humeral evaluation for ruling out concurrent tumors.

  19. Intracranial epidermoid cyst causing recurrent chemically-induced meningitis

    International Nuclear Information System (INIS)

    We present a patient with a epidermoid cyst (EC) located in the prepontine and prebulbar region. The presenting sign was recurrent chemically-induced meningitis. We show the computed tomography (CT) and magnetic resonance (MR) findings. The tumor presented two neuroradiological features of interest. On the one hand, it was impossible to diagnosis it on the basis of the CT study owing to the artifact introduced by the petrous structures at the cranial base. Some of the features of the EC presented here are unusual in this type of lesions. For example, at the same time in the same tumor there are two areas with different compositions which, in the MR study, were found to having clearly different signals. (Author) 9 refs

  20. A CHEESY AFFAIR! - REPORT OF A CASE OF AN EPIDERMOID CYST OF PAROTID

    Directory of Open Access Journals (Sweden)

    Balasubramanian Thaigarajan

    2013-06-01

    Full Text Available This article is a report of a case of epidermoid cyst of the deep lobe of the left parotid, being reported and described for the benefit of the readers in view of the rarity of the condition.

  1. Intradural Epidermoid Cyst at Conus Medullaris and Cauda Equina of the Spine: A Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Mn Woo; Lee, Ji Hae; Cho, Woo Ho [Dept. of Radiology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul (Korea, Republic of)

    2012-02-15

    Spinal epidermoid cysts occur as a result of anomalous implants of epidermal cells within the spinal cord. Spinal epidermoid cysts comprise < 1% of all intraspinal mass lesions and may be congenital or acquired. Congenital lesions usually occur at conus or cauda equina, and the latter usually occur at lower lumbar spine. The typical MR appearance of a spinal epidermoid cyst is a hypointense signal lesion on T1-weighted images and a hyperintense signal lesion on T2-weighted images. However, atypical imaging features also have been reported. In this article, we report atypical MR findings of an intradural epidermoid cyst at conus medullaris and cauda equina of the spine that was caused by internal cystic hemorrhage.

  2. Perspectives for the treatment of epidermoid oesophageal cancer

    International Nuclear Information System (INIS)

    Prior to the eighties, most patients with a diagnosis of epidermoid oesophageal cancer only received palliative symptomatic care. To date, most all undergo either surgery or medical treatment or both. Late diagnosis due to lack of clinical signs in the early phases of the disease, and perhaps insufficient attempts at identifying patients at risk who could benefit from systematic screening, is still an important problem although the number of diagnosed cases continues to rise (from 104 in 1985 to 151 in 1989 in Finistere in western France). Two different therapeutic attitudes could improve the prognosis: extensive surgery as proposed by the Japanese with dissection of all invaded lymph nodes whatever the localization and a multimodal approach combining radiochemotherapy and surgery. Although outcome can apparently be improved in certain types of oesophageal cancer, the proposal of aggressive extensive dissection could have an effect on respiratory complications and would not necessarily be adapted to the risk involved in western patients. Certain teams have nevertheless taken this route and will soon report their results. In France two phase II trials combining radiotherapy, chemotherapy (cisplatinium) and surgery have reported encouraging results with complete sterilization in 24% of the cases and 50% survival at 18 months. In our own series of 68 patients, we have obtained 41% sterilization and 56,3% survival at 3 years with the multi-modal protocol. The high number on non-responders to chemotherapy emphasizes the importance of maintaining surgical resection whenever possible. The discouraging reports published before 1980 have been contradicted by improvements in outcome achieved over the last decade. Today, all patients with a diagnosis of epidermoid cancer of the oesophagus should benefit from either palliative or curative care based on the latest advances in radiotherapy, chemotherapy and surgery. (author). 10 refs

  3. Congenital Epidermoid Cyst Results in Muscle Fusion Defect in the Upper Lip

    OpenAIRE

    Dogan, Fatih; Bucak, Ibrahim Hakan

    2014-01-01

    Epidermoid cysts are rarely detected malformations in the oral cavity. Their development sites are the sublingual, submaxillary, and submandibular spaces. In this paper, we report a three-month-old infant who was admitted to our hospital due upper lip swelling. Magnetic resonance imaging showed that she had a two-centimeter cystic lesion and fusion defects of orbicularis oris muscle. The cyst was surgically removed and histopathological diagnosis was “epidermoid cyst.” In recent literature, w...

  4. Association between testicular microlithiasis, testicular cancer, cryptorchidism and history of ascending testis

    Directory of Open Access Journals (Sweden)

    Stamatiou Konstantinos

    2006-08-01

    Full Text Available OBJECTIVE: To prospectively determine the prevalence of testicular microlithiasis in symptomatic patients who were referred for scrotal ultrasound examination and to evaluate the possible association of testicular microlithiasis with testicular cancer and other conditions such as cryptorchidism or history of ascending testis. MATERIALS AND METHODS: 391 men who were referred to our institutions between July 2002 and May 2005 for any type of symptoms from the testicles, underwent physical and scrotal ultrasound examination. The presence of testicular microlithiasis, the number of lesions and the involvement of both testicles in relation to the symptoms as well as the coexistence of other lesions were studied. RESULTS: Eighteen (4.6% of 391 men enrolled into the study had testicular microlithiasis. Two out of the eighteen patients (11% had concomitant testicular cancer, which was confirmed by pathological evaluation of the orchidectomy specimen. One of the patients with testicular microlithiasis presented a rising in biochemical tumor markers (LDH, and HCG and underwent orchidectomy one year later. Five of the remaining 373 (1.3% patients without microlithiasis were diagnosed with testicular cancer. Thirty six men reported having a history of ascending testis, but none of them was found with testicular cancer. Two cases of testicular torsion in a cryptorchid position had testicular microlithiasis, but the orchidectomy specimen (after surgery was negative for testicular cancer. The correlation between testicular cancer and testicular microlithiasis found in our study was statistically significant (p < 0.05. CONCLUSION: There seems to be an association between testicular microlithiasis and testicular cancer.

  5. Diffusion tensor mode in imaging of intracranial epidermoid cysts: one step ahead of fractional anisotropy

    Energy Technology Data Exchange (ETDEWEB)

    Jolapara, Milan; Kesavadas, Chandrasekharan; Saini, Jitender; Patro, Satya Narayan; Gupta, Arun Kumar; Kapilamoorthy, Tirur Raman; Bodhey, Narendra [Sree Chitra Tirunal Institute for Medical Sciences and Technology, Department of Imaging Sciences and Interventional Radiology, Trivandrum (India); Radhakrishnan, V.V. [Sree Chitra Tirunal Institute for Medical Sciences and Technology, Department of Pathology, Trivandrum (India)

    2009-02-15

    The signal characteristics of an epidermoid on T2-weighted imaging have been attributed to the presence of increased water content within the tumor. In this study, we explore the utility of diffusion tensor imaging (DTI) and diffusion tensor metrics (DTM) in knowing the microstructural anatomy of epidermoid cysts. DTI was performed in ten patients with epidermoid cysts. Directionally averaged mean diffusivity (D{sub av}), exponential diffusion, and DTM-like fractional anisotropy (FA), diffusion tensor mode (mode), linear (CL), planar (CP), and spherical (CS) anisotropy were measured from the tumor as well as from the normal-looking white matter. Epidermoid cysts showed high FA. However, D{sub av} and exponential diffusion values did not show any restriction of diffusion. Diffusion tensor mode values were near -1, and CP values were high within the tumor. This suggested preferential diffusion of water molecules along a two-dimensional geometry (plane) in epidermoid cysts, which could be attributed to the parallel-layered arrangement of keratin filaments and flakes within these tumors. Thus, advanced imaging modalities like DTI with DTM can provide information regarding the microstructural anatomy of the epidermoid cysts. (orig.)

  6. Diffusion tensor mode in imaging of intracranial epidermoid cysts: one step ahead of fractional anisotropy

    International Nuclear Information System (INIS)

    The signal characteristics of an epidermoid on T2-weighted imaging have been attributed to the presence of increased water content within the tumor. In this study, we explore the utility of diffusion tensor imaging (DTI) and diffusion tensor metrics (DTM) in knowing the microstructural anatomy of epidermoid cysts. DTI was performed in ten patients with epidermoid cysts. Directionally averaged mean diffusivity (Dav), exponential diffusion, and DTM-like fractional anisotropy (FA), diffusion tensor mode (mode), linear (CL), planar (CP), and spherical (CS) anisotropy were measured from the tumor as well as from the normal-looking white matter. Epidermoid cysts showed high FA. However, Dav and exponential diffusion values did not show any restriction of diffusion. Diffusion tensor mode values were near -1, and CP values were high within the tumor. This suggested preferential diffusion of water molecules along a two-dimensional geometry (plane) in epidermoid cysts, which could be attributed to the parallel-layered arrangement of keratin filaments and flakes within these tumors. Thus, advanced imaging modalities like DTI with DTM can provide information regarding the microstructural anatomy of the epidermoid cysts. (orig.)

  7. Do We Know What Causes Testicular Cancer?

    Science.gov (United States)

    ... Next Topic Can testicular cancer be prevented? Do we know what causes testicular cancer? The exact cause ... cell, half of which are from each parent. We usually look like our parents because they are ...

  8. Carcinoma epidermoide no queratinizante de células grandes y pequeñas en vagina / Large and small cells non-keratinizing epidermoid vaginal carcinoma

    Scientific Electronic Library Online (English)

    Ofelia, Masó Anaya; María Elena, Morales Larramendi; Dolores, Díaz Pérez; Esperanza, Dager Dager; Gloria Adelaida, Bolaños Diego.

    2012-03-01

    Full Text Available Se presentan 5 casos clínicos de pacientes atendidas en la consulta de patología de cuello del Hospital Provincial Ginecoobstétrico "Mariana Grajales Coello" de Santiago de Cuba por presentar sangrado vaginal, dolor en bajo vientre, leucorrea y lesiones vaginales. El estudio anatomopatológico confir [...] mó el diagnóstico de carcinoma de células escamosas o epidermoide. Abstract in english Five case reports of patients who were assisted at the cervix Pathology Department from "Mariana Grajales Coello" Provincial Gynecological Obstetrical Hospital in Santiago de Cuba due to vaginal bleeding, low abdominal pain, leukorrhea and vaginal injuries are presented. The pathological study confi [...] rmed the diagnosis of squamous or epidermoid cells carcinoma.

  9. Histological evidence of testicular dysgenesis in contralateral biopsies from 218 patients with testicular germ cell cancer

    DEFF Research Database (Denmark)

    Hoei-Hansen, Christina E; Holm, Mette; Rajpert-De Meyts, Ewa; Skakkebæk, Niels Erik

    2003-01-01

    This study was prompted by a hypothesis that testicular germ cell cancer may be aetiologically linked to other male reproductive abnormalities as a part of the so-called 'testicular dysgenesis syndrome' (TDS). To corroborate the hypothesis of a common association of germ cell cancer with testicular dysgenesis, microscopic dysgenetic features were quantified in contralateral testicular biopsies in patients with a testicular germ cell tumour. Two hundred and eighty consecutive contralateral testic...

  10. MANEJO LAPAROSCOPICO CONSERVADOR DE QUISTE DERMOIDE CONTENIENDO UNA MANDIBULA Y 13 DIENTES

    Directory of Open Access Journals (Sweden)

    Jaime Zarhi T.

    2002-01-01

    Full Text Available Se presenta un caso clínico de quiste dermoide abordado en forma conservadora vía laparoscópica conteniendo maxilar superior y trece dientes, se discute su cuadro clínico, diagnóstico y tratamientoA case is presented of conservative laparoscopic excision of an ovarian dermoid cyst which contained a superior mandible with thirteen teeth. The clinical issue, diagnosis and treatment are discussed

  11. MANEJO LAPAROSCOPICO CONSERVADOR DE QUISTE DERMOIDE CONTENIENDO UNA MANDIBULA Y 13 DIENTES

    Scientific Electronic Library Online (English)

    Jaime, Zarhi T.; Juan M., Toso L..

    Full Text Available Se presenta un caso clínico de quiste dermoide abordado en forma conservadora vía laparoscópica conteniendo maxilar superior y trece dientes, se discute su cuadro clínico, diagnóstico y tratamiento [...] Abstract in english A case is presented of conservative laparoscopic excision of an ovarian dermoid cyst which contained a superior mandible with thirteen teeth. The clinical issue, diagnosis and treatment are discussed [...

  12. Quiste mesentérico: experiencia en 4 casos / Mesenteric cyst: experience in 4 cases

    Scientific Electronic Library Online (English)

    David, Martínez-Ramos; Carlos, Rodríguez-Pereira; Javier, Escrig-Sos; Pellicer Castell, Vicente; Juan Manuel, Miralles-Tena; José Luis, Salvador-Sanchís.

    2005-12-01

    Full Text Available El quiste mesentérico es una enfermedad poco frecuente, cuya importancia ha sido menospreciada en demasiadas ocasiones en la literatura médica. La baja incidencia de la enfermedad y la creencia errónea de que se trata de un proceso benigno y asintomático han contribuido al escaso interés por su cono [...] cimiento. Se realizó un estudio retrospectivo con revisión de los pacientes ingresados en el Servicio de Cirugía General y Digestiva del Hospital General de Castellón entre enero de 1990 y noviembre de 2005. Se diagnosticaron 4 quistes mesentéricos de los 34 355 ingresos en nuestro servicio. La mitad eran mujeres y la media de edad fue de 25 años. Tres casos presentaron síntomas y sólo uno fue un hallazgo casual. La manifestación clínica más frecuente fue el dolor abdominal leve y difuso. Uno de los pacientes se complicó con una perforación espontánea del quiste y peritonitis. El tratamiento fue la exéresis quirúrgica en todos los casos. Las vías de abordaje fueron: 3 laparotomías y 1 laparoscopia. Únicamente un caso requirió resección intestinal por déficit en la vascularización. No hubo ninguna recidiva tras la cirugía. A pesar de la baja frecuencia de esta enfermedad, su conocimiento es necesario ya que se pueden presentar síntomas cuando el quiste ha crecido, así como complicaciones graves (hemorragia, perforación, obstrucción intestinal, malignización, etc.), que se pueden prevenir con la intervención quirúrgica, incluso en los casos asintomáticos

  13. QUISTE DE INCLUSIÓN EPIDÉRMICO VULVAR COMO COMPLICACIÓN TARDÍA DE CIRCUNCISIÓN RITUAL

    Scientific Electronic Library Online (English)

    Jorge Andrés, Robert S; Roberto, Yazigi I; Paolo, Ricci A; Antonio, Piottante B.

    Full Text Available Presentamos un caso de quiste de inclusión epidérmico, como complicación tardía, en una mujer africana con antecedente de mutilación genital tipo II o clitoridectomía total, durante su infancia. [...] Abstract in english We report a case of epidermal inclusion cyst as a late complication in an African woman with history of ritual genital mutilation type II or total excision during childhood. [...

  14. QUISTE DE INCLUSIÓN EPIDÉRMICO VULVAR COMO COMPLICACIÓN TARDÍA DE CIRCUNCISIÓN RITUAL

    Directory of Open Access Journals (Sweden)

    Jorge Andrés Robert S

    2010-01-01

    Full Text Available Presentamos un caso de quiste de inclusión epidérmico, como complicación tardía, en una mujer africana con antecedente de mutilación genital tipo II o clitoridectomía total, durante su infancia.We report a case of epidermal inclusion cyst as a late complication in an African woman with history of ritual genital mutilation type II or total excision during childhood.

  15. Enucleación de quiste periapical simultáneo a la obturación del sistema de conductos radiculares

    Directory of Open Access Journals (Sweden)

    Lida Velazque

    2014-06-01

    Full Text Available Introducción: los quistes periapicales representan el tipo más frecuente dentro de los quistes odontogénicos. Su origen está relacionado con una necrosis pulpar y un consecuente estímulo de los restos epiteliales del ligamento periodontal (Malassez. Objetivo: describir un caso clínico de enucleación de quiste periapical simultáneo a la obturación del sistema de conductos radiculares. Presentación del caso: paciente de sexo femenino, 67 años de edad, sin alteraciones sistémicas; buscó atención odontológica por presentar dolor dental y acúmulo de alimentos en la región de molares inferiores del lado izquierdo. Al examen clínico se observó caries extensa en el segundo molar inferior izquierdo con compromiso de furca, ausencia de aumento de volumen vestibular, sin fistula; en la radiografía periapical se evidenció lesión cariosa extensa recidivante en el segundo molar inferior izquierdo, y primer molar inferior izquierdo con tratamiento endodóntico y presencia de área radiolúcida de contornos bien definidos en la región periapical compatible con quiste periapical. El tratamiento estuvo a cargo de un equipo multidisciplinario por lo que se decidió realizar exodoncia del segundo molar inferior izquierdo y cirugía paraendodóntica con enucleación quirúrgica simultánea a la obturación del sistema de conductos radiculares primer molar inferior izquierdo; el examen histopatológico de la muestra extraída comprobó tratarse de un quiste periapical. Se realizó seguimiento radiográfico dos años después y mostró un completo reparo óseo del área afectada. Conclusiones: se concluye que el tratamiento descrito constituye una alternativa válida para la resolución de casos donde la endodoncia convencional es limitada para mantener la función y estética de una pieza dentaria.

  16. Varicocele testicular en adolescentes / Testicular varicocele in adolescent

    Scientific Electronic Library Online (English)

    Daniel, Vásquez E; Carolina, Díaz; Zenen, Carmona; Fernando, Vásquez R.

    2009-12-01

    Full Text Available El varicocele testicular es una patología asociada a la infertilidad del varón. Su mayor prevalencia se presenta en la adolescencia y existen reportes que sugieren que desde esta edad el desarrollo de la espermatogénesis de los adolescentes con varicocele se encuentra comprometido en comparación con [...] los que no lo tienen. Hay que tener presente dos situaciones: una relacionada con las causas por las cuales se presentan las varices y el reflujo venoso en las venas testiculares y su tratamiento, y otra, el daño que ocasionan las varices en la espermatogénesis. Este artículo presenta una revisión de los hallazgos más importantes que explican los mecanismos de la alteración de la fertilidad del varón adolescente que presenta varicocele, por lo que se hace necesario realizar otros estudios que complementen estos hallazgos. Abstract in english The testicular varicocele is a pathology associated with male infertility. Its highest prevalence occurs in adolescence and there are reports that suggest that from this age the development of spermatogenesis in adolescents with varicocele is compromised compared with those without. It is necessary [...] to have present two situations: one related to the causes which have varicose veins and venous reflux in the testicular veins and their treatment and other damage caused varicose veins in spermatogenesis. This article presents a review of the most important findings that explain the mechanisms of the impaired fertility of male adolescents with varicocele

  17. Association between testicular microlithiasis, testicular cancer, cryptorchidism and history of ascending testis

    Scientific Electronic Library Online (English)

    Stamatiou, Konstantinos; Alevizos, Alevizos; Mariolis, Anargiros; Mihas, Constantinos; Halazonitis, Athanase; Bovis, Konstantinos; Eleftherios, Michail; Sofras, Fragiskos.

    2006-08-01

    Full Text Available OBJECTIVE: To prospectively determine the prevalence of testicular microlithiasis in symptomatic patients who were referred for scrotal ultrasound examination and to evaluate the possible association of testicular microlithiasis with testicular cancer and other conditions such as cryptorchidism or h [...] istory of ascending testis. MATERIALS AND METHODS: 391 men who were referred to our institutions between July 2002 and May 2005 for any type of symptoms from the testicles, underwent physical and scrotal ultrasound examination. The presence of testicular microlithiasis, the number of lesions and the involvement of both testicles in relation to the symptoms as well as the coexistence of other lesions were studied. RESULTS: Eighteen (4.6%) of 391 men enrolled into the study had testicular microlithiasis. Two out of the eighteen patients (11%) had concomitant testicular cancer, which was confirmed by pathological evaluation of the orchidectomy specimen. One of the patients with testicular microlithiasis presented a rising in biochemical tumor markers (LDH, and HCG) and underwent orchidectomy one year later. Five of the remaining 373 (1.3%) patients without microlithiasis were diagnosed with testicular cancer. Thirty six men reported having a history of ascending testis, but none of them was found with testicular cancer. Two cases of testicular torsion in a cryptorchid position had testicular microlithiasis, but the orchidectomy specimen (after surgery) was negative for testicular cancer. The correlation between testicular cancer and testicular microlithiasis found in our study was statistically significant (p

  18. Drugs Approved for Testicular Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for testicular cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.

  19. Vulvar Epidermoid Cyst and Type 2 Radical Genital Mutilation.

    Science.gov (United States)

    Birge, Ozer; Ozbey, Ertugrul Gazi; Arslan, Deniz; Erkan, Mustafa Melih; Demir, Feyza; Akgor, Utku

    2015-01-01

    About 100 million women are estimated to be circumcised globally. Various rates of complications have been encountered, especially after circumcision, such as bleeding, infection, shock, menstrual irregularity, difficulty in urination or common urinary tract infections, inguinal pain, difficulty in sexual intercourse, and genital circumcision scar especially at the vulvar region, and cystic or solid character mass in short and long term. Furthermore, the maternal-fetal morbidity and mortality increase due to bleeding and fistula, which develop after prolonged labor, travail, and difficult labors. Our aim in this paper was to discuss a 42-year-old multiparous female case who had undergone type 2 radical genital mutilation (circumcision) when she was 7 years of age, along with the literature, which has been evaluated for the gradually growing mass at the left inguinal canal region in the last 10 years and diagnosed as epidermoid inclusion cyst developing secondary to postcircumcision surgical ground trauma, since there was no other case found in the literature search that had been circumcised at such an early age and developing after circumcision at such advanced age, and, therefore, this is suggested to be the first case on this subject. PMID:26682078

  20. Natural flavonoid derivatives as oral human epidermoid carcinoma cell inhibitors.

    Science.gov (United States)

    Gunda, Shravan Kumar; Kongaleti, Sofia Florence; Shaik, Mahmood

    2015-01-01

    Natural flavonoid derivatives against cancer for selective KB cell lines (oral human epidermoid carcinoma) are analysed to determine the relationship between biological activities and structural properties of these molecules. Molecular alignment was performed for 88 natural flavonoid derivatives; out of these 88 molecules, 69 molecules were taken into training set and rest of the 19 molecules were used in test set prediction. We describe our elucidation of their structure activity relation (SAR) using three-dimensional quantitative structure activity relationship (3D-QSAR) models. A predictive comparative molecular field analysis (CoMFA) model of q² = 0.888 and r² = 0.940 was obtained and a comparative molecular similarity indices analysis (CoMSIA) model q² = 0.778 and r² = 0.971 was used to describe the non-linearly combined affinity of each functional group in the inhibitors. The contour maps obtained from 3D-QSAR studies were evaluated for the activity trends of the molecules analysed. PMID:25869317

  1. Intracranial germinoma in the pineal region arising after subtotal resection of epidermoid cyst: case report.

    Science.gov (United States)

    Walker, Amanda J; Huynh-Le, Minh-Phuong; Nauen, David; Malayeri, Ashkan A; Jallo, George; Terezakis, Stephanie A

    2014-05-01

    We present an unusual case of a germinoma of the pineal region arising adjacent to an epidermoid cyst in a 16-year-old male. Initial imaging findings were classic for epidermoid cyst. The patient underwent two partial resections at an outside institution, each specimen demonstrating pure epidermoid cyst. Follow-up imaging over a period of 24 months showed an area of progressive contrast enhancement adjacent to the initial lesion, suggesting the development of a neoplasm. Given the area of contrast enhancement in addition to worsening headaches and visual changes, he underwent a third and final resection at our institution. Pathology revealed a mixed germ cell tumor with prominent germinoma component in addition to a well-differentiated epidermoid cyst. Details of his imaging and pathologic findings are presented, and possible explanations for these findings are explored, the most likely of which is lack of complete resection at the onset failed to identify the whole of the neoplasm. We conclude that pediatric epidermoid cysts of the pineal region should always receive close follow-up, particularly when total resection is not performed. PMID:24221216

  2. Epidermoid carcinoma of the skin mimicking breast cancer / Carcinoma epidermoide na pele da mama simulando câncer de mama

    Scientific Electronic Library Online (English)

    Baltasar, Melo Neto; Giuliano da Paz, Oliveira; Sabas Carlos, Vieira; Livio Rodrigues, Leal; José Andrade de Carvalho, Melo Junior; Cyro Franklin, Vieira.

    2013-04-01

    Full Text Available O câncer de pele não-melanoma é o câncer mais frequente no mundo. O carcinoma espinocelular ocorre mais frequentemente em áreas expostas ao sol como cabeça e pescoço. Quando o carcinoma espinocelular se desenvolve na região da mama, ulcerando e invadindo o tecido glandular, pode simular um câncer de [...] mama. A confirmação histopatológica, aliada à história clínica, é ferramenta importante para o diagnóstico correto. Apresentamos um caso de carcinoma epidermóide da pele da mama diagnosticado inicialmente como câncer de mama. Abstract in english Nonmelanoma skin cancer is the most frequent cancer in the world. Squamous cell cancer often occurs in sun-exposed areas, such as the head and neck. When it involves the breast and ulce-rates, invading the glandular parenchyma, it may mimic breast cancer. Confirmation by means of histopathological e [...] xamination, combined with clinical examination, is a critical instrument for the accuracy of the diagnosis. We report a case of an epidermoid carcinoma located on the breast skin, initially diagnosed as breast cancer.

  3. Genetics Home Reference: 46,XX testicular disorder of sex development

    Science.gov (United States)

    ... disorder catalog Conditions > 46,XX testicular disorder of sex development On this page: Description Genetic changes Inheritance ... 2008 What is 46,XX testicular disorder of sex development? 46,XX testicular disorder of sex development ...

  4. Quiste de uraco infectado en edad infantil / Infected urachal cyst during childhood

    Scientific Electronic Library Online (English)

    V., Gimeno Argente; C., Domínguez Hinarejos; A., Serrano Durbá; F., Estornell Moragues; M., Martínez Verduch; F., García Ibarra.

    2006-12-01

    Full Text Available Los quistes de uraco son anomalías congénitas detectadas con mayor frecuencia en la infancia. Suelen manifestarse cuando se infectan, simulando diversas patologías agudas intraabdominales o pélvicas. Presentamos un caso en una niña de 7 años diagnosticada de quiste de uraco infectado. Analizamos el [...] origen embriológico de esta patología, sus formas de presentación clínica y sus aspectos diagnóstico-terapéuticos. Abstract in english Urachal cysts are congenital anomalies detected predominantly during the childhood. They are often diagnosed when an infection occur mimicking a variety of acute intra-abdominal or pelvic processes. We present a case in a 7-year-old female infant, diagnosed of infected urachal cyst. The embryologic [...] origin of this anomaly, clinical features, diagnosis and treatment are discussed.

  5. Quiste mesentérico en el recién nacido Mesenteric cyst present in newborn

    Directory of Open Access Journals (Sweden)

    Eduardo Morales Mesa

    2009-09-01

    Full Text Available El quiste mesentérico es una enfermedad rara en la etapa neonatal, y suele confundirse imagenológicamente con múltiples patologías de los órganos intraabdominales. Se presenta un caso clínico con diagnóstico prenatal por imagen anecoica del hemiabdomen superior. El paciente requirió múltiples intervenciones quirúrgicas por presentar un quiste mesentérico que coexistía con atresia intestinal ileal en forma de «cáscara de manzana», y el tratamiento clínico y nutricional fue difícil.Mesenteric cyst is a rare condition in neonatal stage and often is confounded with multiple pathologies of intra-abdominal organs. A clinical case diagnosed with prenatal diagnosis by anechoic image of superior hemi-abdomen. Patient required of many surgical interventions due to a mesenteric cyst coexisting with an "apple shell" ileal intestinal atresia. Clinical and nutritional treatment was difficult.

  6. Quiste mesentérico en el recién nacido / Mesenteric cyst present in newborn

    Scientific Electronic Library Online (English)

    Eduardo, Morales Mesa; Nilvia Esther, González García; Maria de los Ángeles, Cubero Rego; Lissette, Trelles Porro.

    2009-09-01

    Full Text Available El quiste mesentérico es una enfermedad rara en la etapa neonatal, y suele confundirse imagenológicamente con múltiples patologías de los órganos intraabdominales. Se presenta un caso clínico con diagnóstico prenatal por imagen anecoica del hemiabdomen superior. El paciente requirió múltiples interv [...] enciones quirúrgicas por presentar un quiste mesentérico que coexistía con atresia intestinal ileal en forma de «cáscara de manzana», y el tratamiento clínico y nutricional fue difícil. Abstract in english Mesenteric cyst is a rare condition in neonatal stage and often is confounded with multiple pathologies of intra-abdominal organs. A clinical case diagnosed with prenatal diagnosis by anechoic image of superior hemi-abdomen. Patient required of many surgical interventions due to a mesenteric cyst co [...] existing with an "apple shell" ileal intestinal atresia. Clinical and nutritional treatment was difficult.

  7. Quiste residual gigante: presentación de un caso / Residual cyst: a case presentation

    Scientific Electronic Library Online (English)

    Oscar, Rivero Pérez; Carlos, Albornoz López del Castillo; Isidro de Jesús, Nápoles González.

    2014-10-15

    Full Text Available Fundamento: un quiste es una estructura con tendencia a la forma redondeada, constituida por una pared externa de tejido conectivo fibroso, una pared interna formada por un tapiz epitelial. La cavidad quística contiene un material líquido o semilíquido de color cetrino que, cuando se infecta, se con [...] vierte en purulento y carmelitoso. El quiste residual puede haber sido anteriormente un quiste lateral o un quiste apical y al haberse extraído el diente, a partir de cuyo periodonto se forma el quiste, se queda en el tejido óseo sin haber sido extirpado. Objetivo: presentar un caso al cual se le diagnosticó y trató un quiste residual mandibular que abarcaba la hemiarcada izquierda, que permitió restablecer las funciones masticatorias y estética. Caso Clínico: paciente que fue atendido en la consulta de Cirugía Maxilofacial de la Facultad de Estomatología de Camagüey, con un aumento de volumen en la región lateral izquierda, con antecedentes de trauma anterior que le provocó fractura de mandíbula. Se describen las características clínicas de la enfermedad y el tratamiento quirúrgico realizado, se utilizó para el mismo los principios de la técnica de enucleación. Conclusiones: aunque se han reportados pocos casos en la literatura nacional y extranjera, estos han sido quistes de menor tamaño que incluyen uno o dos dientes, no existen reportes de quistes residuales que involucren toda la arcada o hemiarcada dentaria. Se obtuvieron resultados estéticos satisfactorios con la técnica quirúrgica empleada y no se presentaron complicaciones. Abstract in english Background: a cyst is a structure with a tendency to be rounded, made up of an external wall of fibrous connective tissue, an internal wall composed of epithelial tissue. The cystose cavity contains sallow liquid or semiliquid material that, when becomes infected, gets purulent and brown. A residual [...] cyst could have been previously a lateral cyst or an apical cyst and when the tooth is extracted from the periodontium, the cyst remains in the osseous tissue without being removed. Objective: to present a case diagnosed and treated for a mandibular residual cyst that extended over the left hemiarcade. It was possible to re-establish the masticatory and aesthetic functions. Clinical case: a patient who was treated in the Maxillofacial Surgery consultation of the Faculty of Stomatology of Camagüey. The patient presented a volume increase in the left lateral region and an antecedent of front trauma that caused fracture of the lower jaw. The clinical characteristics of the disease and the surgical treatment conducted are described. The principles of the enucleation technique were used for conducting the surgical treatment. Conclusions: in spite of the fact that few cases have been reported in the national and foreign literature, these have been smaller cysts that included one or two teeth. There are no reports of residual cysts that extend over all the dental arcade or hemiarcade. Satisfactory aesthetic results were obtained with the surgical technique applied and there were no complications.

  8. Leech therapy for epidermoid cysts and review of the literature

    Directory of Open Access Journals (Sweden)

    Abbas Rasi

    2014-01-01

    Full Text Available Hirudo medicinalis sucks blood directly through the external mammalian skin. We recently observed a healthy 64-year-old Iranian man, who presented with numerous asymptomatic multilobular oval-to-round well-defined 0.5 to 1.5 cm cystic lesions with central umbilication (central black eschar over the upper portion of his chest. We made the diagnosis of epidermoid cyst, giant comedone and leech bite on the basis of the constellation of clinical features. The patient was treated with oral ciprofloxacin at a dose of 2 g daily, and 2% topical erythromycin solution. Despite improvement, the evidence of cystic lesions persisted. There was no history of similar lesions in any other family member. There was no history of trauma. The patient was not using any topical or systemic medication. Two weeks before his visit, he had a history of leech therapy under the supervision of a general practitioner. His medical history was significant for leech therapy of the lesions, five days previously. He was followed up for another two weeks and after disappearance of the inflammation, with the patient under local anesthesia, the well-circumscribed mass was completely evacuated with a sharp curette and comedone extractor. The patient was subsequently lost to follow-up. Conclusion: Considering the efficacy of leeches, it would be favorable to breed a germ-free leech. In Iran, the use of the leeches in surgery, in recent years, has been infrequent. It appears that the positive effects of this ancient remedy may now be explained through scientific methods, promising potentially even more uses of this admirable creature in medicine.

  9. Testicular size in young adult Sinhalese.

    Science.gov (United States)

    Wikramanayake, E

    1995-06-01

    Height, body weight, arm span and testicular size were measured in 200 Sinhalese men aged 21-31 years. The mean +/- SD right testicular size was 17.2 + 4.1 ml and that of the left was 16.1 + 3.9 ml. The testes were of equal size in 75% and the right testis was larger in 20% of the men. The prevalence of undescended testes was 2%. There as a significant correlation of testicular size with weight (p < 0.05) and a significant correlation of right testicular size with span (p < 0.01). Testicular size was not correlated with height or body mass index. Although the Sinhalese are ethnically closer to the Caucasians, their testicular size is similar to that reported by previously for Thai men. PMID:7558385

  10. Quiste dermoide del suelo de la boca Dermoid cyst in the mouth floor

    Directory of Open Access Journals (Sweden)

    Ayelén María Portelles Massó

    2010-12-01

    Full Text Available El quiste dermoide representa menos del 0,01 % de todos los quistes de la cavidad bucal. Su ubicación más frecuente es en suelo de boca. Se presenta el caso de una paciente femenina de 19 años de edad que hacía aproximadamente 7 años había notado un aumento de volumen debajo de la lengua, el cual le crecía paulatinamente y ya se apreciaba por fuera de la cara. Además, le ocasionaba molestias al hablar y al masticar. Se realizaron estudios complementarios y bajo anestesia general nasotraqueal. Se procedió a su exéresis quirúrgica mediante un abordaje intrabucal, donde se obtuvieron excelentes resultados estéticos y funcionales. El diagnóstico histopatológico se correspondió con un quiste dermoide de suelo de boca. La paciente no ha tenido recurrencia de la lesión transcurridos tres años de la operación. El quiste dermoide de suelo de boca se presenta como una tumoración benigna de la línea media. La exéresis intrabucal demuestra beneficios estéticos y funcionales.The Dermoid cyst account for the 0.01 % of all cysts of buccal cavity. Its more frequent location is in the mouth floor. This is the case of a female patient aged 19 who approximately 7 years noted an increase of volume under tongue growing gradually and noting outside face and the discomfort at to speak and to chew. Complementary studies were conducted and under general anesthesia a surgical exeresis was carried out by intrabuccal approach achieving excellent esthetic and functional results. Histopathologic diagnosis matched with a dermoid cyst of mouth floor. Patient has not lesion recurrence after three years after operation. We conclude that the Dermoid cyst of mouth floor appear as benign tumor of middle line. The intrabuccal exeresis demonstrates esthetic and functional benefits.

  11. Quiste dermoide del suelo de la boca / Dermoid cyst in the mouth floor

    Scientific Electronic Library Online (English)

    Ayelén María, Portelles Massó; Ailín Tamara, Torres Íñiguez.

    2010-12-01

    Full Text Available El quiste dermoide representa menos del 0,01 % de todos los quistes de la cavidad bucal. Su ubicación más frecuente es en suelo de boca. Se presenta el caso de una paciente femenina de 19 años de edad que hacía aproximadamente 7 años había notado un aumento de volumen debajo de la lengua, el cual le [...] crecía paulatinamente y ya se apreciaba por fuera de la cara. Además, le ocasionaba molestias al hablar y al masticar. Se realizaron estudios complementarios y bajo anestesia general nasotraqueal. Se procedió a su exéresis quirúrgica mediante un abordaje intrabucal, donde se obtuvieron excelentes resultados estéticos y funcionales. El diagnóstico histopatológico se correspondió con un quiste dermoide de suelo de boca. La paciente no ha tenido recurrencia de la lesión transcurridos tres años de la operación. El quiste dermoide de suelo de boca se presenta como una tumoración benigna de la línea media. La exéresis intrabucal demuestra beneficios estéticos y funcionales. Abstract in english The Dermoid cyst account for the 0.01 % of all cysts of buccal cavity. Its more frequent location is in the mouth floor. This is the case of a female patient aged 19 who approximately 7 years noted an increase of volume under tongue growing gradually and noting outside face and the discomfort at to [...] speak and to chew. Complementary studies were conducted and under general anesthesia a surgical exeresis was carried out by intrabuccal approach achieving excellent esthetic and functional results. Histopathologic diagnosis matched with a dermoid cyst of mouth floor. Patient has not lesion recurrence after three years after operation. We conclude that the Dermoid cyst of mouth floor appear as benign tumor of middle line. The intrabuccal exeresis demonstrates esthetic and functional benefits.

  12. Presentación clínica atípica de un quiste dentígero / Atypical clinical presentation of a dentigerous cyst

    Scientific Electronic Library Online (English)

    Denia, Morales Navarro; Guillermo, Sánchez Acuña; Liliana, Rodríguez Lay.

    2009-12-01

    Full Text Available Los quistes dentígeros suelen ser, en la mayor parte de los casos, un hallazgo casual; por lo general se descubren al investigar la no erupción de un diente permanente. Ocupan el segundo lugar en frecuencia de aparición en los maxilares después del quiste radicular. Cuando el seno maxilar es invadid [...] o por estos quistes los síntomas usualmente aparecen tardíos en el proceso. Estos pueden incluir dolor facial, parestesia como consecuencia de la presión sobre un nervio, dolor de cabeza, trismo, trastornos de la gustación y congestión nasal. Por lo infrecuente de la localización maxilar y la corta edad de la paciente nos vimos motivados a revisar lo más reciente de la bibliografía que aborda este tema y a presentar el caso clínico de una paciente femenina de 17 años que fue diagnosticada y tratada por presentar un quiste dentígero en dicha ubicación. Se enfatiza en la importancia del correcto diagnóstico y el establecimiento de una terapéutica concordante en cada caso. Abstract in english Dentigerous cysts are a casual finding in most of cases, in general discovered in investigation of a not eruption of permanent tooth. These occupy the second place in appearance frequency in maxillaries after radicular cyst. When maxillary sinus is invaded by these cysts, symptoms usually appear lat [...] e in the process. These could include facial pain, paresthesia as consequence of pressure on nerve, headache, trismus, taste disorders and nasal congestion. Due the infrequent of the maxillary location and the short age of patient we reviewed the more recent of bibliography on this subject and to present the clinical case of other female patient aged 17 diagnosed with and treated by dentigerous cyst in such location, emphasizing on the significance of a appropriate diagnosis and establishment of a therapy in accord in each case

  13. From gonocytes to testicular cancer

    DEFF Research Database (Denmark)

    Rajpert-de Meyts, Ewa; Hoei-Hansen, Christina E

    2007-01-01

    highly developed industrialized countries. A hypothesis was put forward that CIS originates from arrested fetal germ cells, thus testicular cancer is a developmental disease of germ-cell differentiation. This notion was supported by comparative studies of the gene expression at the protein and RNA level......, which demonstrated a close similarity of CIS to primordial germ cells and gonocytes with many features of embryonic stem cells. The arrest of germ-cell differentiation is thus the key first event, which may be followed by malignant transformation and overt germ-cell cancer in young adult age, usually....... The most severe cases are a result of inherited genetic aberrations, but the etiology of the common sporadic testicular cancer must involve environmental factors, including maternal lifestyle and possibly an early exposure to endocrine disruptors. The effects of environmental factors are likely...

  14. Polygenic susceptibility to testicular cancer

    DEFF Research Database (Denmark)

    Litchfield, Kevin; Mitchell, Jonathan S; Shipley, Janet; Huddart, Robert; Rajpert-De Meyts, Ewa; Skakkebæk, Niels E; Houlston, Richard S; Turnbull, Clare

    2015-01-01

    BACKGROUND: The increasing incidence of testicular germ cell tumour (TGCT) combined with its strong heritable basis suggests that stratified screening for the early detection of TGCT may be clinically useful. We modelled the efficiency of such a personalised screening approach, based on genetic...... risk profiling in combination with other diagnostic tools. METHODS: We compared the number of cases potentially detectable in the population under a number of screening models. The polygenic risk scoring (PRS) model was assumed to have a log-normal relative risk distribution across the 19 currently...... known TGCT susceptibility variants. The diagnostic performance of testicular biopsy and non-invasive semen analysis was also assessed, within a simulated combined screening programme. RESULTS: The area under the curve for the TGCT PRS model was 0.72 with individuals in the top 1% of the PRS having a...

  15. Tumores testiculares en la infancia / Testicular Tumours in Infancy and children

    Scientific Electronic Library Online (English)

    A., Bujons; J., Caffaratti; M., Pascual; O., Angerri; J.M., Garat; H., Villavicencio.

    2011-02-01

    Full Text Available Introducción: los tumores testiculares prepuberales son distintos a los que se presentan en la edad adulta. Tradicionalmente han sido considerados malignos, pero realmente los tumores testiculares benignos son más frecuentes en esta edad. Material y métodos: revisamos nuestra experiencia en el trata [...] miento de los tumores testiculares en niños Abstract in english Introduction: prepubertal testicular tumours are different from those that appear during adulthood. Traditionally, they were considered to be malignant, however benign testicular tumours are actually more frequent at this age. Materials and methods: we analysed our experience in the treatment of tes [...] ticular tumours in children

  16. MANEJO LAPAROSCÓPICO DE QUISTES OVÁRICOS COMPLICADOS O PERSISTENTES DURANTE EL EMBARAZO

    Directory of Open Access Journals (Sweden)

    José Luis Troncoso J

    2009-01-01

    Full Text Available Antecedentes: El incremento en el hallazgo de quistes anexiales durante el embarazo sería el mayor uso de técnicas de reproducción asistida con hiperestimulación ovárica controlada. La complicación más frecuente sigue siendo la torsión anexial. Objetivo: Revisar el manejo de quistes anexiales complicados o persistentes, durante el embarazo, con resolución laparoscópica. Método: Revisión retrospectiva de 9 pacientes consecutivas, ingresadas al Departamento de Obstetricia y Ginecología Clínica Las Condes. Resultados: La edad gestacional de ingreso fue entre 5+5 y 27 semanas. Cinco casos fueron producto de fertilización asistida y cuatro espontáneos. Ocho (85,6% embarazadas, ingresaron por dolor abdominal agudo. Otro caso ingresó a cirugía electiva por quiste ovárico persistente. Los quistes tenían entre 6 y 13 cm. En 5 se realizó sólo destorsión ovárica, en 1 ooforectomía y en 1 quistectomía. Se realizó punción, destorsión y fijación a ligamento útero ovárico, bilateral, en la otra paciente. Se registró un caso de fiebre en el postoperatorio. El alta hospitalaria fue a las 48 horas en 6 (67%, a las 72 en 2 y a las 96 en 1. El estudio biópsico diferido en 3 pacientes demostró: 1 quiste seroso paratubario, 1 quiste luteínico parcialmente hemorrágico y 1 infarto anexial. Todos los embarazos evolucionaron normalmente. Conclusión: Nuestra experiencia confirma que en el embarazo la laparoscopía es una buena opción al requerir una cirugía por quiste anexial complicado o persistente.Background: Recent reviews show an increase in the finding of adnexal cysts during pregnancy. One reason could be the use of assisted reproductive techniques with controlled ovarian hyperstimulation. Objective: To review the experience in managing via laparoscopy complicated or persistent adnexal cysts during pregnancy. Method: Retrospective review of 9 consecutive patients, admitted at the Department of Obstetrics and Gynecology, Clínica Las Condes. Results: The gestational age was between 5+5 and 27 weeks. Five were the product of assisted fertilization and four spontaneous. Eight (85.6% pregnant women were admitted by emergency room because of acute abdominal pain and another one went through elective surgery for persistent ovarian cyst. Preoperative diagnosis of the 8 patients admitted by emergency: adnexal cyst complicated with torsion in 6 (1 adnexal infarction and 2 cases of acute abdomen. The cysts were between 6 and 13 cm. Type of surgery: in 5, only detorsión; ovarian oophorectomy in 1 and cystectomy in one. Puncture, detorsión and bilateral fixation of uterine ovarian ligament, in another patient. One case required conversion to laparotomy with adnexectomy. Postoperative fever was observed in one patient. Discharge was at 48 hrs in 6 (67% cases, at 72 hrs. in 2 and 96 hrs. in 1. Deferred biopsy performed in 3 patients showed: paratu-barian serous cyst, partially hemorrhagic luteal cyst, adnexal infarction. All pregnancies went on normally. Premature births are not reported. Conclusion: Our experience suggests that laparoscopic approach is a valid option for complicated or persistent adnexal cysts in pregnant women.

  17. Histological evidence of testicular dysgenesis in contralateral biopsies from 218 patients with testicular germ cell cancer

    DEFF Research Database (Denmark)

    Hoei-Hansen, Christina E; Holm, Mette; Rajpert-De Meyts, Ewa; Skakkebæk, Niels Erik

    2003-01-01

    This study was prompted by a hypothesis that testicular germ cell cancer may be aetiologically linked to other male reproductive abnormalities as a part of the so-called 'testicular dysgenesis syndrome' (TDS). To corroborate the hypothesis of a common association of germ cell cancer with testicular...... dysgenesis, microscopic dysgenetic features were quantified in contralateral testicular biopsies in patients with a testicular germ cell tumour. Two hundred and eighty consecutive contralateral testicular biopsies from Danish patients with testicular cancer diagnosed in 1998-2001 were evaluated...... retrospectively. Two hundred and eighteen specimens were subsequently included in this study, after 63 patients who did not meet inclusion criteria had to be excluded. The presence of carcinoma in situ (which is believed to originate from transformed gonocytes) was detected in 8.7% of biopsies. The incidence of...

  18. Quistes foliculares en vacas posparto y su evolución con tratamiento de GnRH Y PGF2

    Directory of Open Access Journals (Sweden)

    Leonardo Duque Muñoz

    2011-01-01

    Full Text Available Introduccion. Se analizaron retrospectivamente datos reproductivos en un lapso de tiempo cercano a 18 meses, en cinco hatos lecheros del municipio de San Pedro de los Milagros (Ant, con una poblacion de 950 vacas. Objetivo. Analizar la evolucion del tratamiento a vacas con quistes foliculares. Materiales y metodos. Las vacas fueron tratadas con GnRH a doble dosis y a los 14 dias PGF2¿¿. Si persistio el quiste se repitio dos veces mas el tratamiento. Analisis estadistico. Los datos fueron analizados utilizando el software SAS con un Anova, considerando como significativos todos los datos con un p<0,05. Resultados. Se encontro una frecuencia de presentacion de quistes en posparto tardio de 8,9 %; el porcentaje de vacas que resolvieron el problema al primer tratamiento fue de 74,1 %, con un promedio de 87,3 dias de diagnostico posparto, al segundo 10,5 % con 141,8 dias promedio y 3,5 % al tercero con 189,3 dias al diagnostico; el porcentaje de vacas descartadas fue de 11,8 %. Conclusiones. Este analisis retrospectivo de cinco hatos lecheros, demuestra que se presentan con relativa frecuencia quistes foliculares en el posparto tardio, pero se pueden solucionar efectivamente si se diagnostican en los primeros 90 dias, ademas el tratamiento realizado despues de detectado el quiste folicular entre 80-90 dias posparto, es efectivo para resolver el 74,12% de los casos, con una tasa de prenez del 70,5%.

  19. Tumor canceroso testicular: Seminoma clásico / Testicular Cancer Tumor: Classic Seminoma

    Scientific Electronic Library Online (English)

    Paola Danitza, Luizaga Velasco; Luis Antonio, Luizaga Velasco; Boris, Mejia Arce; Sandra, Campuzano J..

    Full Text Available El tumor canceroso tipo seminoma es el cáncer testicular más frecuente, afecta con mayor frecuencia a las personas de una edad media de 50 años. El seminoma presenta factores de riesgo como criptorquidia, infertilidad y antecedentes familiares de primer grado con cáncer. La estadificación determina [...] la extensión de la invasión hacia órganos vecinos; TNM (Tumor, Nódulo, Metástasis). El diagnóstico se realiza por la clínica, se observa una masa creciente de gran volumen, pero también se usa Marcadores Tumorales; como la Alfa feto proteína, la cual es negativa siempre para seminoma y B Gonadotrofina Coriónica Humana, la cual con muy poca frecuencia está elevada. Entre los métodos de imagen que se usan están la Radiografía de tórax, Tomografía de abdomen y pelvis para descartar metástasis. Se presenta un caso de un paciente de 52 años de edad, con una masa voluminosa testicular- indolora, de unos 7 años de evolución que desde hace 2 meses presenta puntos de hemorragia externa. Al examen físico presenta una masa de 18 por 15 cm, con un punto de hemorragia en la región escrotal y secreción purulenta en el prepucio, posteriormente se procede al tratamiento adecuado. Abstract in english The cancerous tumor type seminoma is the most common testicular cancer, most frequently affects people of an average age of 50 years. The seminoma presents risk factors such as cryptorchidism, infertility, and a family history of first grade with cancer. Staging determines the extent of invasion int [...] o neighbouring organs; TNM (Tumor, nodule, Metastasis). The diagnosis is carried out by the clinic there is a growing mass of high-volume, but also used tumoral markers; as the alpha protein, which is always negative to seminoma and fetal Human B Chorionic Gonadotropin, which rarely is elevated. The methods of image that are used include chest radiograph and tomography of abdomen and pelvis to rule out metastasis. A case of a patient's 52 years of age, with a bulky mass testicular - painless, about 7 years of evolution from 2 months ago has points of external bleeding. A physical exam presents a mass of 18 by 15 cm, with a point of hemorrhage in the scrotal region and purulent secretion in the foreskin, and then proceeds to the appropriate treatment.

  20. Association of an Epidermoid Tumour with Ipsilateral Aneurysms of Middle Cerebral Artery Bifurcation and Anterior Communicating Artery

    Directory of Open Access Journals (Sweden)

    Gokhan KURT

    2010-06-01

    Full Text Available By this case report the authors are aimed to describe an unusual case of epidermoid tumour associated with ipsilateral two cerebral aneurysms. Radiological and clinical findings of a 45 year old male patient are described. Investigation of the patient revealed a right temporal lobe tumour and ipsilateral two aneurysms. The patient is treated with micro-neurosurgery successfully. Both the tumour and the right MCA aneurysm are interfereted in the same session. His pathological diagnose was epidermoid tumour. Togetherness of epidermoid tumours and cerebral aneurysms is a very rare entity. Further studies are needed to demonstrate the exact pathological and genetic mechanisms.

  1. Current Clinical Applications of Testicular Cancer Biomarkers.

    Science.gov (United States)

    Mir, Maria C; Pavan, Nicola; Gonzalgo, Mark L

    2016-02-01

    Current use of testicular biomarkers for screening, diagnosis, and follow-up is reviewed in the context of potential clinical utility of these tests. This information will be of value to clinicians to determine patient suitability for certain treatments and will also assist in reviewing current literature regarding potential biomarkers that may be used for testicular cancer. PMID:26614034

  2. 21 CFR 876.3750 - Testicular prosthesis.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Testicular prosthesis. 876.3750 Section 876.3750 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GASTROENTEROLOGY-UROLOGY DEVICES Prosthetic Devices § 876.3750 Testicular prosthesis....

  3. CISS MR imaging findings of epidermoid tumor : comparison with spin-echo images

    International Nuclear Information System (INIS)

    To evaluate CISS MR imaging findings of epidermoid tumor in comparison with conventional spin-echo images. We studied 6 cases of epidermoid tumor in the subarachnoid space. We used a 1.5T MR unit to obtain CISS images(TR/TE/FA ; 12.3msec/5.9 msec/700) and T1- and T2- weighted spin-echo images. CISS MR imaging findings were evaluated with respect to tumor's signal intensity , contour, and relation with adjacent structures. Conspicuity of the tumor was compared between CISS and spin-echo images. A quantitative analysis was performed by measuring tumor to CSF contrast. In qualitative analysis, three radiologists independently compared CISS image and conventional spin-echo images for visibility of the tumor and graded them into three categories( poor, good, and excellent). Epidermoid tumors were located in the cerebellopontine angle in 4 cases, the prepontine cisstern in 1 case, and the cerebellopontine angle-prepontine cistern in 1 case. The tumors were hyperintense relative to brain parenchyma and hypointense relative to CSF on CISS images, were lobulated, encased adjacent cranial nerve and vessels, and invaginated into brain parenchyma. In qualitative analysis, CISS images showed clear demarcation between tumor and CSF, exact tumor extension, and tumor's relation with cranial nerves and vessels better than conventional spin-echo images. In quantitative analysis, the mean contrast values of tumor to CSF on T1-, T2-weighted images, and CISS images were 0.12, 0.06, and 0.52, respectively. The contrast value for CISS images was significantly higher than that for T1-and T2-weighted images(p<0.05). Epidermoid tumors in the subarachnoid space are better demonstrated on CISS images than on conventional spin-echo images. This special MR sequence can be added as a routine protocol in the diagnosis of subarachnoid epidermoid tumor

  4. Testicular Cancer, Version 2.2015.

    Science.gov (United States)

    Motzer, Robert J; Jonasch, Eric; Agarwal, Neeraj; Beard, Clair; Bhayani, Sam; Bolger, Graeme B; Chang, Sam S; Choueiri, Toni K; Costello, Brian A; Derweesh, Ithaar H; Gupta, Shilpa; Hancock, Steven L; Kim, Jenny J; Kuzel, Timothy M; Lam, Elaine T; Lau, Clayton; Levine, Ellis G; Lin, Daniel W; Michaelson, M Dror; Olencki, Thomas; Pili, Roberto; Plimack, Elizabeth R; Rampersaud, Edward N; Redman, Bruce G; Ryan, Charles J; Sheinfeld, Joel; Shuch, Brian; Sircar, Kanishka; Somer, Brad; Wilder, Richard B; Dwyer, Mary; Kumar, Rashmi

    2015-06-01

    Germ cell tumors (GCTs) account for 95% of testicular cancers. Testicular GCTs constitute the most common solid tumor in men between the ages of 20 and 34 years, and the incidence of testicular GCTs has been increasing in the past 2 decades. Testicular GCTs are classified into 2 broad groups--pure seminoma and nonseminoma--which are treated differently. Pure seminomas, unlike nonseminomas, are more likely to be localized to the testis at presentation. Nonseminoma is the more clinically aggressive tumor associated with elevated serum concentrations of alphafetoprotein (AFP). The diagnosis of a seminoma is restricted to pure seminoma histology and a normal serum concentration of AFP. When both seminoma and elements of a nonseminoma are present, management follows that for a nonseminoma. The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Testicular Cancer outline the diagnosis, workup, risk assessment, treatment, and follow-up schedules for patients with both pure seminoma and nonseminoma. PMID:26085393

  5. Familial testicular cancer and developmental anomalies

    International Nuclear Information System (INIS)

    Familial occurrence belongs to factors followed in etiology and pathogenesis of testicular germ-cell tumors. Association with abnormal testicular development, or with other risk factors is relatively frequent. In our material 650 patients had been treated for testicular cancer in the period of 1981-1995. Familial occurrence was observed 7-times (1.08), most frequently in combination with cryptorchidism. Individual families were analyzed in details, including HLA typing. On basis of the observations the supplementation of initial examination of each patient with suspicious testicular cancer with detailed familiar history aimed also at the occurrence of urogenital developmental anomalies and tumors has been recommended. The knowledge about familial tumor occurrence in the first-degree relatives in combination with thorough testicular self-examination is being considered of great importance in the secondary prevention. (author)

  6. Carcinoma broncogénico epidermoide en un hombre de 21 años Epidermoid bronchogenic carcinoma in a 21 year old black man

    Directory of Open Access Journals (Sweden)

    John Jairo Duque Alzate

    1999-01-01

    Full Text Available Hombre de 21 años de edad de raza negra, natural del Chocó (Colombia, quien ha desempeñado diversos oficios; presentó un síndrome de dificultad respiratoria de dos meses de evolución, dolor pleurítico derecho, insuficiencia cardíaca congestiva y síntomas sistémicos. En la necropsia se encontró una masa tumoral blanco-grisácea de 10 x 8 cm, homogénea, con áreas de necrosis, originada en el bronquio principal de los lóbulos inferior y medio derechos y que invadió por vecindad en forma de coraza todo el pericardio causando una pericarditis constrictiva tumoral. El estudio microscópico correspondió a un carcinoma broncogénico tipo epidermoide bien diferenciado. El carcinoma broncogénico se asocia frecuentemente con el consumo de cigarrillo pero su incidencia ha c.umentado entre las personas no fumadoras, lo que sugiere la posibilidad de otros factores que influyen en su presentación como son los contaminantes atmósféricos, la predisposición genética, la dieta deficiente en vitamina A y carotenos, la presencia de ciertos virus y cambios inmunológicos. Este tumor constituye el 16% de todos los cánceres en el hombre y e113% en las mujeres; aparece con mayor frecuencia entre los 40 y los 70 años y sólo del1 al 5% de los casos se presenta en menores de 40 años. A 21 year cid black man, native from Chocó (Colombia, variously employed, who presented with a respiratory difficulty syndrome of two months of evolution, right pleuritic pain, congestive cardiac failure and systemic symptoms. A homogeneic white .grayish tumor measuring 8 by 10 cm with necrotic areas was found at necropsy. The tumor originated in the main bronchial tube of the lower and middle lobes of the right lung and invaded the entire pericardial vicinity forming a cuirass and causing tumoral constrictive pericarditis. Microscopic studies revealed a well differentiated squamous type bronchogenic carcinoma. Bronchogenic carcinomas are frequently associated with cigarette smoking. However, their incidente has increased among non. smokers, suggesting the possibility that there are other causal factors, such as atmospheric contaminants, genetic predisposition, diets deficient in vitamin A and carotene, presente of certain viruses and immunologic changes. Lung cancer constitutes 16% among the types of cancer suffered by men and 13% among women, it has its greatest incidente in groups between 40 and 70 years of age and only 1 to 5 percent of thecasesoccur in groupsunder theageofforty years.

  7. Radiation Therapy of Testicular Seminoma

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Hong Gyun; Oh, Do Hoon; Ha, Sung Whan [Seoul National University College of Medicine, Seoul (Korea, Republic of)

    1994-10-15

    Purpose: Testicular seminomas are radiosensitive and adjuvant radiation therapy after orchiectomy results in long term survival in early stage diseases. Ten year results of radiation therapy after orchiectomy and results of definitive treatment of recurrent seminoma are presented. Materials and Methods: Between August 1980 and February 1990, 32 patients with testicular seminomas were treated at the Department of Therapeutic Radiology, Seoul National University Hospital. Twenty-seven patients received radiation therapy after orchiectomy and 5 patients for treatment of recurrent tumors. Two of postoperatively treated patients and 2 of recurrent patients were excluded from the study because of incomplete treatment. Of the patients treated postoperatively. 18 were stage I, 5 were stage IIA, one was stage IIB, and one was stage IIC. There were 4 ipsilateral and 2 contralateral cryptorchids. Preoperatively, b-HCG levels were elevated in 5 patients. Median dose to pelvic and paraaortic lymph node area was 2900 cGy (1550-4550 cGy). One patient with stage I, 4 with stage IIA, and 1 with stage IIB received prophylactic mediastinal irradiation. Two patients were treated with chemotherapy before radiation therapy. Median follow-up period was 104(3-144) months. Result: Local control rates were 100% at 5 years after orchiectomy. Five year survival rates were 94.4% in Stage I and 100% in Stage II patients. One patient with stage I disease died 3 months after surgery due to mediastinal metastasis. All the 3 patients treated for recurrent disease are alive without disease. Conclusion: Postorchiectomy radiation to the pelvis and para-aortic area remains the treatment of choice for patient with early stage testicular seminoma. Radiation therapy is also an excellent treatment modality for recurrent seminoma.

  8. Ultrassonografia testicular em caprinos jovens da raça Alpina / Testicular ultrasonography in young Alpine goats

    Scientific Electronic Library Online (English)

    L.R.B., Carazo; J.D., Guimarães; T.P., Machado; T.P.L.C., Machado; F.A.S.A.M., Oliveira; D.B., Pereira.

    2014-04-01

    Full Text Available Objetivou-se com este trabalho observar as mudanças do parênquima testicular de acordo com o fotoperíodo e com a faixa etária dos animais por meio da ecotextura testicular e a viabilidade do uso do ultrassom na avaliação testicular. Foram utilizados 4 animais desde o 6° até o 13° mês de idade. Os ex [...] ames ecográficos foram realizados a cada 15 dias para avaliar a ecotextura testicular. O parênquima testicular mostrou-se moderadamente ecogênico e homogêneo. Foi observado comportamento semelhante na ecotextura testicular durante o período de avaliação, sendo maior no 8º mês de idade, quando o volume testicular também foi maior; tais mudanças foram relacionadas com o fotoperíodo da região. A avaliação ultrassonográfica dos testículos mostrou-se um método eficiente, capaz de detectar as mudanças no parênquima testicular ao longo do tempo, e como ferramenta alternativa para diferenciação de condições normais e patológicas em caprinos. Abstract in english The purpose of this study was to observe changes in the testicular parenchyma of male goats. Changes were observed in terms of goat age, evaluating the echotexture and ultrasound viability in the testicles. Four animals were used, ranging from six to 13 months of age. The echographic examinations we [...] re performed every 15 days to assess echotexture of the testicle. The testicular parenchyma appeared moderately echogenic and homogeneous. Similar results were observed in testicular echotexture during the evaluation period. The highest results appearing during the eighth month of age, when the testicular volume was also highest; such changes were related to the regional photoperiod. The ultrasound evaluation of the testicles was shown to be an effective method, ultimately capable of detecting changes in testicular parenchyma over time, being an alternative to differentiation normal and pathological conditions in goats.

  9. [The cytological diagnostics of dysplasia and epidermoid carcinoma of the cervix in studying the nucleolar-organizing regions of chromosomes].

    Science.gov (United States)

    Bolgova, L S; Tuganova, T N; Alekseenko, O I

    2012-11-01

    The study of the nucleolar-organizing regions of chromosomes in the cells of dys-plastically modified squamous epithelium and epidermoid cancer of cervix was carried out. The successive increase of quantita-tive content of main morphofunctional types of nucleoli is established including active compact and transient nucleolonemic-compact ones in accordance with in-crease of dysplastic modifications and appearance of signs of epidermoid cancer of cervix. The dominance of percentage content of large argyrophilic granules in nu-cleoli of nucleolonemic type under epidermoid cancer of cervix as compared with dysplasia is established. The algorithm of differentiating cytological diagnostics of the degree of dysplasia and epidermoid cancer of cervix is developed. This algo-rithm reflects the degree of structural functional modifications of nucleolar-organizing regions of chromosomes. PMID:23305016

  10. Quiste renal gigante. Presentación de un caso / Giant renal cyst. Presentation of a case

    Scientific Electronic Library Online (English)

    Teresa, Suárez Díaz; Yuniel, Arocha Molina; Ariel, Jordán Alonso; Roberto, Ruiz Reyes; Adianez, Jiménez Álvarez.

    2013-08-01

    Full Text Available En el riñón frecuentemente se desarrollan quistes. Dentro de la diversidad de quistes renales, el simple puede presentarse dentro del riñón o en la superficie de este pudiendo, ser único o múltiple, unilateral o bilateral y más frecuente en el izquierdo. Generalmente se manifiestan asintomático y pu [...] eden alcanzar gran tamaño, denominándose quistes gigantes. Se presenta un paciente de 66 años que ingresa por dolor lumbar hace un año, que empeora a pesar del tratamiento médico para una presunta sacrolumbalgia. En el abdomen se aprecia marcado aumento de volumen, sobre todo hacia el hemiabdomen superior y se palpa gran masa tumoral que ocupa la totalidad del hemiabdomen superior, renitente y no dolorosa. Se realizó tomografía axial computarizada de abdomen, apreciándose imagen hipodensa multitabicada que ocupa todo el hemiabdomen izquierdo con desplazamiento de asas, riñón izquierdo y músculo psoas. Se concluye como quiste gigante multitabicado de riñón izquierdo. Se realizó laparotomía paramediana izquierda supra e infraumbilical y se detecta gran quiste renal del polo superior del riñón izquierdo que sobrepasa la línea media desplazando la arteria aorta a la derecha de la columna vertebral. Se realizó nefrectomía izquierda. Es raro, que un quiste renal simple gigante, sobrepase la línea media y tenga compresión de tantos órganos intraabdominales; este es un hecho poco descrito en la literatura médica. El examen físico superficial y limitado al órgano que produce los síntomas que motivan la consulta, limita el diagnóstico precoz de muchas enfermedades como se demuestra en este paciente. Este es uno de los errores más frecuentes que se aprecian al aplicar el método clínico. Abstract in english Frequently, cysts develop in the kidney. Among the diversity of renal cysts, the simple one could be located inside the kidney or in its surface and may be single or multiple, unilateral or bilateral, and more frequent in the left kidney. Generally they are asymptomatic and can reach a great size, c [...] alled giant cysts. We present a patient aged 66 years, entering the hospital with lumbar pain of one year that gets worse despite the medical treatment for a presumed sacrolumbal pain. It was found a remarked increase of the abdomen volume, mainly in the direction of the upper hemiabdomen and it feels a big tumoral mass filling the totality of the upper abdomen, renitent and no painful. An abdominal computer tomography was carried out, finding a multi partitioned hypodense image filling all the left hemiabdomen with displacement of loops, left kidney and psoas muscle. We arrived to the conclusion that it was a giant multi partitioned cyst of the left kidney. A left paramedian supra and infra umbilical laparotomy was carried out finding a renal cyst of the upper pole of the left kidney surpassing media line and displacing aortal artery to the right of the spinal column. A left nephrectomy was carried out. It is rare a simple renal giant cyst surpassing the media line and compressing so many intra abdominal organs; this is a fact scarcely described in the medical literature. The surface physical examination restricted to the organ producing the symptoms that motivate the consultation, interferes the precocious diagnosis of many diseases as it is shown in this patient. This is one of the most frequent mistakes committed when applying the clinical method.

  11. Tratamiento del quiste óseo solitario con energía piramidal / Treatment of the solitary bone cyst with pyramidal energy

    Scientific Electronic Library Online (English)

    Reinaldo, Viera García; Martín, Rodríguez Barrios; Francisco, Carcasés Osorio; Eduardo, Borges Romero; Percyvals, Cabrera Feurtado.

    2009-12-01

    Full Text Available Se describe el caso clínico de una niña con fractura patológica recurrente a causa de un quiste óseo solitario en el tercio superior del húmero izquierdo. La aplicación de la energía piramidal constituyó una técnica terapéutica eficaz para eliminar el mencionado quiste. [...] Abstract in english The clinical case of a girl with recurrent pathological fracture due to a solitary bone cyst in the upper third of the left humerus is described. Application of pyramidal energy was an effective therapeutic technique to remove this cyst. [...

  12. Retención aguda de orina, "RAO", como presentación de quiste de uraco / Urachal cyst presentated as acute urinary retention

    Scientific Electronic Library Online (English)

    C., Quicios Dorado; E., Fernández Fernández; I., Gómez García; D., García Flórez; C. de, Castro Guerin; A., Escudero Barrilero.

    2005-10-01

    Full Text Available El quiste de uraco esta presente aproximadamente en el 2% de los adultos, siendo su diagnostico difícil y secundario a las manifestaciones de su complicaciones. Presentamos un caso inusual de retención aguda de orina en un quiste de uraco, que debutó como dolor hipogástrico y anuria. [...] Abstract in english 2% of adults have an urachal cyst. The diagnosis is usually made due to its clinical complications. We report an inusual case of acute urinary retention due to an urachal cyst, with hipogastric pain and anuria as initial syntoms. [...

  13. Tumor canceroso testicular: Seminoma clásico

    Directory of Open Access Journals (Sweden)

    Campuzano J. Sandra

    2011-06-01

    Full Text Available El tumor canceroso tipo seminoma es el cáncer testicular más frecuente, afecta con mayor frecuencia a las personasde una edad media de 50 años. El seminoma presenta factores de riesgo como criptorquidia, infertilidad y antecedentes familiares de primer grado con cáncer. La estadificación determina la extensión de la invasión hacia órganos vecinos; TNM (Tumor, Nódulo, Metástasis. El diagnóstico se realiza por la clínica, se observa una masa crecientede gran volumen, pero también se usa Marcadores Tumorales; como la Alfa feto proteína, la cual es negativa siempre para seminoma y B Gonadotrofina Coriónica Humana, la cual con muy poca frecuencia está elevada. Entre los métodos de imagen que se usan están la Radiografía de tórax, Tomografía de abdomen y pelvis para descartar metástasis. Se presenta un caso de un paciente de 52 años de edad, con una masa voluminosa testicular- indolora, de unos 7 años de evolución que desde hace 2 meses presenta puntos de hemorragia externa. Al examen físico presenta una masa de 18 por 15 cm, con un punto de hemorragia en la región escrotal y secreción purulenta en el prepucio, posteriormente se procede al tratamiento adecuado.

  14. Quiste de inclusión conjuntival gigante. Presentación de un caso / Cyst of inclusion conjunctival giant. Case presentation

    Scientific Electronic Library Online (English)

    Isabel, Medina Rodríguez; Beatriz, Zozaya Aldana; Henry, Pérez González; Yanet, García Concha; René Faustino, Espinosa Álvarez.

    2012-03-01

    Full Text Available Introducción: El Quiste de inclusión conjuntival gigante, forma parte de los quistes de inclusión epitelial, y en la literatura revisada solo se reportan esporádicos casos, asociados en la mayoría de ellos a cirugías previas, donde las células epiteliales son capturadas por la sutura e implantados e [...] n otros sitios Presentación del caso: Se describe el caso en paciente de 19 años, piel negra, oriunda de Malí, África, portadora de una lesión tumoral conjuntival, la cual recibió tratamiento médico sintomático durante 18 meses, sin resolución. Luego de evaluar el caso, se decide exéresis de la lesión con su posterior estudio anatomopatológico. Conclusiones: Se recibe el resultado con el diagnóstico confirmativo: quiste de inclusión conjuntival gigante. Se logró la recuperación total de la paciente. Se finaliza con un breve comentario de esta entidad a través de la literatura consultada. Abstract in english Introduction: The Cyst of conjunctival giant inclusion, form departs from the cysts of epithelial inclusion, and occasional cases, associates report themselves in literature checked only in the their majority to previous surgeries, where epithelial cells are captured by the suture and established at [...] another places. Case presentation: Describes him the case in patient of 19 years, black, native skin of Mali, Africa, beneficiary of a lesion conjunctival tumoral, which he received symptomatic medical treatment during 18 months, without resolution. Right after evaluating the case, makes a decision exéresis of the lesion with his posterior study anatomopatológico. Conclusions: The result with the confirmative diagnosis is received: Cyst of conjunctival giant inclusion. He got for himself the patient's total recuperation. It comes to an end with a brief comment of this entity through looked up literature.

  15. Quiste renal complejo: caso difícil de diagnosticar / Complex renal cyst: a difficult case to diagnose

    Scientific Electronic Library Online (English)

    Odalys, Sandoval Jiménez; Lourdes, Santana Sarrhy.

    2009-12-01

    Full Text Available Se presenta un nuevo caso de un quiste renal complejo que acude a nuestro centro. La paciente tiene 59 años y hace poco tiempo presenta un dolor lumbar izquierdo mantenido, sordo y gravativo; al examen físico se palpa una tumoración en el hipocondrio y flanco izquierdo. Esta entidad no es rara, pero [...] es difícil de diagnosticar pues en múltiples estudios las imágenes complejas indican una posible afectación tumoral maligna y sólo la exploración quirúrgica define el diagnóstico real. Se describen las características de los quistes renales simples y complejos detallando cómo se realiza el diagnóstico imagenológico de estos casos y la conducta que se sigue en dependencia del grado de complejidad del quiste. Se compara la información encontrada en la literatura médica y la experiencia con esta paciente. Se revisa la literatura encontrada sobre el tema y se comenta la problemática en torno al diagnóstico y a las posibilidades terapéuticas. Abstract in english This is the case of a female patient coming to our center presenting with a complex renal cyst. The patient is aged 59 and a short history of a sustained, dull and severe left lumbar pain; at physical examination a hypochondrium tumor in left flank is palpated. This entity is frequent, but is diffic [...] ult to diagnose since in multiple studies complex images show possible malign tumor affection, and only the surgical exploration defines the true diagnosis. Features of the simple and complex renal cysts with details on performing of imaging diagnosis of these cases and the behavior followed according the complexity degree of cyst. Information present in medical literature is compared with experience of this patient. Literature on this matter is reviewed and problems around the diagnosis and the therapeutical possibilities are discussed.

  16. Ultrassonografia testicular em caprinos jovens da raça Alpina

    OpenAIRE

    L.R.B. Carazo; J.D. Guimarães; T.P. Machado; T.P.L.C. Machado; F.A.S.A.M. Oliveira; Pereira, D.B.

    2014-01-01

    Objetivou-se com este trabalho observar as mudanças do parênquima testicular de acordo com o fotoperíodo e com a faixa etária dos animais por meio da ecotextura testicular e a viabilidade do uso do ultrassom na avaliação testicular. Foram utilizados 4 animais desde o 6° até o 13° mês de idade. Os exames ecográficos foram realizados a cada 15 dias para avaliar a ecotextura testicular. O parênquima testicular mostrou-se moderadamente ecogênico e homogêneo. Foi observado comportamento semelhante...

  17. Quiste dermoide verdadero en piso de boca / True dermoid cyst in the floor of the mouth

    Scientific Electronic Library Online (English)

    Daniel, Antunes Freitas; Jessica, Lozano Perez; Luis, Fang Mercado; Antonio, Díaz Caballero.

    2013-09-01

    Full Text Available Los quistes dermoides son lesiones benignas de origen embrionario, con una incidencia del 0,01 % de todos los quistes de la cavidad bucal. No presenta predicción por sexo y alrededor del 60 % de los casos se desarrollan entre los 15 y 35 años de edad. El conocimiento de los hallazgos clínicos de est [...] e tipo lesiones es vital para un diagnóstico definitivo, sin embargo, este siempre debe ser corroborado mediante exámenes histopatológicos, especialmente, al realizar un diagnóstico diferencial entre los diferentes tipos de quiste dermoides u otras alteraciones a nivel oral con manifestaciones clínicas similares. El propósito de esta presentación reportar un caso clínico para ampliar conocimientos sobre el diagnóstico y tratamiento de este tipo de lesión debido a su infrecuencia en cavidad oral. La ubicación inusual de estos quistes en cavidad oral hace que, aún con una buena valoración clínica e imaginológica, el diagnóstico prequirúrgico preciso sea difícil. Es por esto que el tratamiento quirúrgico no sólo evita el riesgo de una complicación infecciosa y eventual malignización sino que permite obtener un diagnóstico definitivo mediante estudios histopatológicos. Abstract in english Dermoid cysts are benign lesions of embryonic origin, with an incidence of 0.01 % of all cysts in the oral cavity. There is no prediction by sex and about 60 % of cases develop at the age of 15 to 35 years old. Knowledge of the clinical findings of such injuries is vital for a definitive diagnosis; [...] however, this should always be confirmed by histopathological examination, especially when making a differential diagnosis between different types of dermoid cyst or other pathologies with similar clinical manifestations. The purpose of this article is to expand knowledge about the diagnosis and treatment of this type of injury because of it is not frequent in the oral cavity. The unusual location of these cysts in the oral cavity makes hard the precise preoperative diagnosis, even with good clinical and radio-graphical assessment. The surgical treatment not only prevents the risk of infectious complications and possible malignancy but also, allows obtaining a definitive diagnosis by a histopathological study.

  18. Testicular cancer: addressing the psychosexual issues.

    LENUS (Irish Health Repository)

    Moore, Annamarie

    2012-01-31

    Testicular cancer is the most common malignancy in men aged 15-35 years and predominantly occurs at a time in a man\\'s life when important decisions about marriage, starting a family and a professional career are being made. While treatments for testicular cancer are very successful, they can have a major impact on the person\\'s sexuality and sense of self. The focus of this article is on exploring the impact of cancer treatments for testicular cancer on men\\'s sexuality and how nurses can respond to their concerns in a sensitive and informed manner.

  19. [Pulmonary sarcoidosis with testicular and epididymal disease].

    Science.gov (United States)

    Calvo Bonachera, J; Sebastián Gil, M D; Bernal Rosique, M S; Calvo Bonachera, M D; Pascual Lledo, F J; Valencia Rodríguez, A

    1999-10-01

    We expose a case of sarcoidosis with pulmonary and intrathoracic ganglion infection added to an infrequent testicular and epididymal affection simultaneously. We only have found this association in six cases in the revised literature, but we didn't found the affection of Morgagni's hydatid by sarcoidosis. The presence of testicular mass and hilar adenopathies in young patients make us to think about a diagnostic threat. The inguinal treatment with testicular biopsy has been chosen like the diagnostic management in this case. PMID:10603671

  20. An unusual presentation of testicular tumor

    International Nuclear Information System (INIS)

    A case of testicular choriocarcinoma is reported in which blood mixed stools and haemoptysis were the presenting manifestations as the patient never told about the testicular swelling to his parents. Orchidectomy was performed but the patient presented again with massive hematemesis due to gastric perforation secondary to gastric metastasis. The size of the testis at diagnosis was approximately 12 x 7cm. This was also unusual as testicular choriocarcinoma presents as a small mass. The patient eventually died of the complications within one month of diagnosis. (author)

  1. Lipid peroxidation in adrenal and testicular microsomes.

    OpenAIRE

    Brogan, W C; Miles, P. R.; Colby, H D

    1981-01-01

    Studies were carried out to determine the actions of and interactions between ascorbate, NADPH, Fe2+, and Fe3+ on lipid peroxidation in adrenal and testicular microsomes. Ascorbate-induced malonaldehyde production was maximal in adrenal and testicular microsomes at an ascorbate concentration of 1 X 10(-4)M. Fe2+, at levels between 10(-6) and 10(-3)M, produced concentration-dependent increases in lipid peroxidation in adrenal and testicular microsomes; Fe2+ had a far greater effect than Fe3+ i...

  2. Carboplatin: a new platinum analog in the treatment of epidermoid carcinoma of the esophagus.

    Science.gov (United States)

    Sternberg, C; Kelsen, D; Dukeman, M; Leichman, L; Heelan, R

    1985-11-01

    Thirty-one patients with advanced epidermoid carcinoma of the esophagus were treated with carboplatin (CBDCA), a second-generation cisplatin analog. Thirty patients were evaluable for response. Major responses (complete response) were seen in two patients (7%; 95% confidence limits, 1%-20%). The median survival from initiation of the protocol was 3 months (range, 0.1-16). Neither renal dysfunction nor emesis was a significant problem with CBDCA; hematologic toxicity was dose-limiting. Thrombocytopenia was more marked than leukopenia. CBDCA is a well-tolerated cisplatin analog that produced two complete responses in patients with advanced epidermoid carcinoma of the esophagus, where such responses are rarely observed. Although the observed response rate was only 7%, the 95% confidence limits overlap those previously reported for cisplatin (12%-31%). PMID:3912041

  3. Testicular myeloid sarcoma: case report

    Directory of Open Access Journals (Sweden)

    Luzia Beatriz Ribeiro Zago

    2013-01-01

    Full Text Available Myeloid sarcomas are extramedullary solid tumors composed of immature granulocytic precursor cells. In association with acute myeloid leukemia and other myeloproliferative disorders, they may arise concurrently with compromised bone marrow related to acute myeloid leukemia, as a relapsed presentation, or occur as the first manifestation. The testicles are considered to be an uncommon site for myeloid sarcomas. No therapeutic strategy has been defined as best but may include chemotherapy, radiotherapy and/or hematopoietic stem cell transplantation. This study reports the evolution of a patient with testicular myeloid sarcoma as the first manifestation of acute myeloid leukemia. The patient initially refused medical treatment and died five months after the clinical condition started.

  4. Testicular myeloid sarcoma: case report

    Scientific Electronic Library Online (English)

    Luzia Beatriz Ribeiro, Zago; Antônio Alexandre Lisbôa, Ladeia; Renata Margarida, Etchebehere; Leonardo Rodrigues de, Oliveira.

    Full Text Available Myeloid sarcomas are extramedullary solid tumors composed of immature granulocytic precursor cells. In association with acute myeloid leukemia and other myeloproliferative disorders, they may arise concurrently with compromised bone marrow related to acute myeloid leukemia, as a relapsed presentatio [...] n, or occur as the first manifestation. The testicles are considered to be an uncommon site for myeloid sarcomas. No therapeutic strategy has been defined as best but may include chemotherapy, radiotherapy and/or hematopoietic stem cell transplantation. This study reports the evolution of a patient with testicular myeloid sarcoma as the first manifestation of acute myeloid leukemia. The patient initially refused medical treatment and died five months after the clinical condition started.

  5. [Epidermoid cyst of the spleen in children. Apropos of 2 cases].

    Science.gov (United States)

    Bourdelat, D; Le Gall, E; Jouan, H; Duval, J M; Babut, J M

    1983-01-01

    Two cases of epidermoid cyst of the spleen are reported. A splenectomy was necessary because the topography of the lesions was not consistent with a conservative procedure for this children fourteen and ten years old. The histological criteria and pathogenic hypotheses of this infrequent lesion are analysed. Ultrasonography and eventually computerized tomography bring the best findings concerning the topography and are useful for the surgical treatment. When it is possible, the partial conservation of the spleen is to be wished. PMID:6627538

  6. Selective apoptotic effect of Zelkova serrata twig extract on mouth epidermoid carcinoma through p53 activation

    OpenAIRE

    Kang, Hoe-Jin; JANG, YOUNG-JOO

    2012-01-01

    Apoptosis or programmed cell death plays an essential role in chemotherapy-induced tumor cell killing, and inducers of apoptosis are commonly used in cancer therapy. Treatment with Zelkova serrata extracts was performed in human gingival fibroblast (HGF), mouth epidermoid carcinoma cell (KB), lower gingival squamous cancer cell (YD38) and tongue mucoepidermoid carcinoma cells (YD15). We observed that extract prepared from Zelkova serrata twig selectively inhibited proliferation of various ora...

  7. The place of radiotherapy in muco-epidermoid carcinomas of salivary glands in child

    International Nuclear Information System (INIS)

    As muco-epidermoid carcinomas are the most frequent tumours of salivary glands for child, the authors report the study of the role of radiotherapy. This study is based on a survey performed in 34 paediatric departments. The authors analyse the age and gender, the use of irradiation, the tumour location, the tumour grade and size, the use of surgery and of radiotherapy, and survival. Radiotherapy is beneficial for high grade tumours, but cannot be recommended for low and intermediate grades. Short communication

  8. Epidermoid carcinomas of the anal margin treated by curative goal irradiation

    International Nuclear Information System (INIS)

    Purpose: to evaluate the toxicity, the local control rate and the survival of patients suffering of an epidermoid carcinoma of the anal margin treated by curative and conservative irradiation. Conclusion: the excision should be reserved for small tumors away from the anal canal. The curative radiotherapy is recommended for the tumors with incomplete resection and for that ones of big volume or localised near the anal canal. (N.C.)

  9. Quiste dermoide en la cola de la ceja / Dermoid cyst in the eyebrow tail

    Scientific Electronic Library Online (English)

    Lázara Kenia, Ramírez García; Datia Liset, Ortiz Ramos; Clara Gisela, Gómez Cabrera; Lázaro, Vigoa Aranguren; Irene, Rojas Rondón; Franklyn Alain, Abreu Perdomo.

    2014-03-01

    Full Text Available El quiste dermoide es un tipo de coristoma que corresponde a una anomalía congénita del desarrollo. Se presenta una transicional de dos años. Desde su nacimiento, la mamá notó un aumento de volumen a nivel de la cola de la ceja del ojo derecho, de bordes delimitados, blanda, movible, reborde orbitar [...] io libre, sin cambios de coloración, con un crecimiento acelerado clínico y ultrasonográfico en meses. Se decidió exéresis y biopsia para estudio anatomopatológico. Los resultados finales mostraron confirmación del diagnóstico de quiste dermoide en la cola de la ceja. La evolución posoperatoria fue satisfactoria sin recidiva de la lesión. Abstract in english The dermoid cyst is a type of choristoma resulting from congenital development anomaly. A 2-year transitional dermoid cyst from birth was discovered by the mother when she noticed increased volume at the tail of the right eyebrow, defined edges, soft, movable, free orbital rim, no color changes with [...] rapid clinical and ultrasonographic growth in months. It was decided to perform excision and biopsy for the pathological study. The final results showed confirmation of the diagnosis of dermoid cyst in tail of the eyebrow. The postoperative course was satisfactory without recurrent injure.

  10. Fibroma ameloblástico versus quiste folicular hiperplásico / Ameloblastic fibroma versus hyperplastic follicular cyst

    Scientific Electronic Library Online (English)

    J., Azúa-Romeo; E., Saura Fillat; T., Usón Bouthelier; M., Tovar Lázaro; J., Azúa Blanco.

    2004-06-01

    Full Text Available Resumen: El fibroma ameloblástico (FA) es un tumor odontogénico mixto, compuesto por tejido mesenquimal y epitelio odontogénico, representando el 2% de los tumores odontogénicos, mientras que el quiste dentígero o folicular (QF), el segundo quiste odontogénico en frecuencia, está compuesto exclusiva [...] mente por tejido conjuntivo laxo (mesénquima), si bien, el saco fibroso puede contener restos de epitelio odontogénico incluidos, dando lugar a una imagen histológica muy similar. La importancia de esta diferenciación radica en el tratamiento, que es ligeramente más agresivo en el FA y en el comportamiento biológico, ya que el FA puede derivar en un sarcoma ameloblástico, y el QF puede evolucionar hacia ameloblastoma y más raramente carcinoma mucoepidermoide. Abstract in english Abstract: Ameloblastic fibroma (AF) is a mixed odontogenic tumor composed of mesenchymal tissue and odontogenic epithelium, accounting for 2% of all odontogenic tumors, while dentigerous or follicular cyst (FQ), second odontogenic cyst in frequency, is formed exclusivelly by soft conective tissue (m [...] esenchyme). Nevertheless, hiperplastic fibrous sac may contain rests of odontogenic epithelium, showing a similar histologic pattern. The importance of an adequate differentiation lies in the treatment, which is slightly aggresive for AF, and regarding the biological behaviour of both lesions, since AF might become in an ameloblastic sarcoma, while over an FQ could develope an ameloblastoma or even a mucoepidermoid carcinoma.

  11. Fibroma ameloblástico versus quiste folicular hiperplásico Ameloblastic fibroma versus hyperplastic follicular cyst

    Directory of Open Access Journals (Sweden)

    J. Azúa-Romeo

    2004-06-01

    Full Text Available Resumen: El fibroma ameloblástico (FA es un tumor odontogénico mixto, compuesto por tejido mesenquimal y epitelio odontogénico, representando el 2% de los tumores odontogénicos, mientras que el quiste dentígero o folicular (QF, el segundo quiste odontogénico en frecuencia, está compuesto exclusivamente por tejido conjuntivo laxo (mesénquima, si bien, el saco fibroso puede contener restos de epitelio odontogénico incluidos, dando lugar a una imagen histológica muy similar. La importancia de esta diferenciación radica en el tratamiento, que es ligeramente más agresivo en el FA y en el comportamiento biológico, ya que el FA puede derivar en un sarcoma ameloblástico, y el QF puede evolucionar hacia ameloblastoma y más raramente carcinoma mucoepidermoide.Abstract: Ameloblastic fibroma (AF is a mixed odontogenic tumor composed of mesenchymal tissue and odontogenic epithelium, accounting for 2% of all odontogenic tumors, while dentigerous or follicular cyst (FQ, second odontogenic cyst in frequency, is formed exclusivelly by soft conective tissue (mesenchyme. Nevertheless, hiperplastic fibrous sac may contain rests of odontogenic epithelium, showing a similar histologic pattern. The importance of an adequate differentiation lies in the treatment, which is slightly aggresive for AF, and regarding the biological behaviour of both lesions, since AF might become in an ameloblastic sarcoma, while over an FQ could develope an ameloblastoma or even a mucoepidermoid carcinoma.

  12. Quiste de Tarlov bilateral, presentación de un caso / Tarlov cyst bilateral , case report

    Scientific Electronic Library Online (English)

    Octavio, Chávez Herbas; Luis Daniel, Parada Heredia; Tonchy, Marinkovic Álvarez.

    2014-12-01

    Full Text Available Los quistes de Tarlov, son crecimientos quísticos benignos sub diagnosticados y no reportándose ningún caso en Bolivia. Son clasificados como quistes meníngeos tipo II, infrecuentes (incidencia estimada de 4,6% - 9%), de características benignas, en su mayoría localizados en región sacra. Asintomáti [...] cos, en su gran mayoría diagnosticados de manera incidental. Se presenta el caso de una paciente con dolor crónico de tipo radicular en fosa iliaca izquierda sin mejoría ni explicación del mismo. Se le realizó tomografía computarizada y resonancia magnética por las cuales se llegó al diagnóstico. Posteriormente se da tratamiento conservador sintomatológico con mejoría evidente de las misma. No requiriendo tratamiento quirúrgico. Abstract in english Tarlov cyst is a benign cystic growth usually underdiagnosed. No case has been reported so far in Bolivia. Classified as a Type II meningeal cysts, rare (estimated incidence of 4,6% - 9%), of benign characteristics, most commonly located in the sacral region. Asymptomatic and diagnosed incidentally [...] most of the times. The patient comes with a chief complaint of chronic radicular back pain in the left iliac fossa with no improvement or explanation thereof. The patient underwent CT and MRI leading us to the diagnosis. The patient is managed with conservative treatment targeting the symptoms, with notorious improvement not requiring surgical treatment.

  13. Giant Ovarian Cyst. A Case Report Quiste de ovario gigante. Presentación de un caso

    Directory of Open Access Journals (Sweden)

    Yarisdey Corrales Hernández

    2012-09-01

    Full Text Available Ovarian cysts are common tumors among gynecological conditions. The case of a 46 years old woman who arrived at the Dr. Gustavo Aldereguía Lima General University Hospital in Cienfuegos, because of pain and swelling of the abdomen of a year of evolution is presented. The physical examination and ultrasound were performed and the patient was diagnosed with an ovarian dependant cystic mass. Laparotomy was performed and the left ovarian cyst was resected. In pathological and anatomical studies the diagnosis of an ovarian serous cystadenoma was confirmed.Los quistes de ovario son tumoraciones frecuentes en las afecciones ginecológicas. Se presenta el   caso de una paciente de 46 años de edad, que acudió al Hospital General Universitario Dr. Gustavo Aldereguía Lima, de Cienfuegos, refiriendo dolor y aumento de volumen del abdomen de un año de evolución. Se realizaron examenes físico y ultrasonográfico, mediante los que se le diagnosticó una masa quística dependiente de ovario. Se practicó laparotomía y se resecó un quiste de ovario izquierdo. En su estudio anatomopatológico se comprobó el diagnóstico de cistoadenoma seroso del ovario.

  14. Cáncer papilar primario en quiste del conducto tirogloso: A propósito de un caso

    Scientific Electronic Library Online (English)

    Ysmael, Vegas; José E, Goubaira; Wilfredo, Perfetti; Juan, Scarton López; José G, López; Verónica, Mora.

    2006-03-01

    Full Text Available El conducto tirogloso es una anomalía congénita resultado de la retención del tracto epitelial entre la tiroides, el foramen cecum y el piso de la faringe. La aparición de un carcinoma en el quiste del conducto tirogloso es rara. Hasta donde sabemos se han publicado 150 casos en la literatura intern [...] acional. Presentamos un caso de carcinoma papilar en un quiste del conducto tirogloso tratado en nuestra institución, el cual representa el único caso tratado en nuestro departamento en un período de 17 años. Abstract in english A thyroglossal duct cyst is a congenital anomaly resulting from retention of an epithelial tract between the thyroid and the foramen cecum, at the floor of the pharynx. Papillary carcinoma originating in a thyroglossal duct cyst is a rare event. As far as we know, only 150 cases of thyroglossal duct [...] cyst carcinoma have been reported in the international literature. We present one case of pa-pillary carcinoma arising in a thyroglossal duct cyst treated at our institution. This is the first case managed by our department in seventeen years.

  15. Cáncer papilar primario en quiste del conducto tirogloso. A propósito de un caso

    Scientific Electronic Library Online (English)

    Ysmael, Vegas; José E., Goubaira; Wilfredo, Perfetti; Juan Scarton, López R.; José G., López; Verónica, Mora.

    2005-07-01

    Full Text Available El conducto tirogloso es una anomalía congénita resultado de la retención del tracto epitelial entre la tiroides, el foramen cecum y el piso de la faringe. La aparición de un carcinoma en el quiste del conducto tirogloso es rara, menor del 1 %. Hasta donde sabemos se han publicado 150 casos en la li [...] teratura internacional. Presentamos un caso de carcinoma papilar en un quiste del conducto tirogloso tratado en el Servicio de Cabeza y Cuello del Instituto de Oncología Dr. Miguel Pérez Carreño (centro de referencia nacional), el cual, representa el único caso tratado en nuestro Instituto en el lapso comprendido desde 1986 y el 2003, (17 años). Abstract in english SUMMARY A thyroglossal duct cyst is a congenital anomaly resulting from retention of epithelial tract between the thyroid and its origin, the foramen cecum, at the floor of the pharynx. Carcinoma papillary originating in thyroglossal duct cyst is a rare event, minor of 1 %. As far as we know, only 1 [...] 50 cases of thyroglosal duct cyst carcinoma have been reported in the international literature. We present a case of papillary carcinoma of thyroglossal duct cyst treated in the Head and Neck Surgery Service of the Instituto Oncológico Dr. Miguel Pérez Carreño (national reference center), which, it represents the only case treated in our Institute in the laps included from 1986 and the 2003, (17 years).

  16. Testicular blood flow in varicocele

    International Nuclear Information System (INIS)

    Radioisotopic scrotal angiography was applied for study of testicular blood flow of patients with varicocele. Following iv. bolus injection of 10 ? 20 mCi of Tc human serum albumine, Tc RBC or Tc pertechnetate, time activity curve of radioactivity at corresponding bilateral areas of scrotum was simultaneously generated and compared. Eighty-four patients with overt varicocele (grade 2 and 3) at left side only, were selected for the present study and eight healthy young volunteers were studied as a control group. Three patterns of time activity curves were recognized. They are as follows. Type 1, where radioactivity was accumulated quickly in left side and then decreased gradually. Bilateral time activity curves were asymmetrical. Type 2, where time activity curves rose gradually and to a higher level at the left side than at the right side. Type 3, where bilateral time activity curves increased gradually, and symmetrically. All of the control group showed the same pattern as Type 3. Of the 84 patients examined, 34 patients showed Type 1, including 7 with grade 2 and 27 with grade 3. Twenty-four patients showed Type 2. consisting of 12 with grade 2 and 12 with grade 3. Twenty-six patients showed Type 3, consisting of 14 with grade 2 and 12 with grade 3. We presumed the following about testicular blood flow in varicocele: Type 1 pattern shows retrograde blood flow from the renal vein to the internal spermatic vein, Type 2 pattern shows poor venous return through the internal spermatic vein and Type 3 pattern shows good venous return though the presence of dilatated pampiniform plexus. (author)

  17. Quiste globulomaxilar de localización inusual: Reporte de un caso An unusual case of globulomaxillary cyst: a case report

    Directory of Open Access Journals (Sweden)

    J. Orozco Ariza

    2009-12-01

    Full Text Available El quiste globulomaxilar es un quiste no odontogénico localizado entre el incisivo lateral y canino del maxilar superior, radiográficamente aparece como una lesión radiolúcida unilocular que desplaza las mencionadas piezas dentarias mostrando una imagen de pera invertida característico de la lesión cuya lámina dura es continua y raras veces interrumpida. La valoración clínica radiográfica es importante para plantear en el diagnóstico diferencial la probable presencia del quiste globulomaxilar. La muestra anatomopatológica debe ser remitida íntegramente para su estudio y diagnóstico definitivo demostrando la presencia de tejido epitelial. Se presenta caso clínico de quiste globulomaxilar en un paciente femenino de 19 años de edad localizado entre canino y primer premolar superior izquierdo.Globulomaxillary cyst is a nonodontogenic cyst usually located between maxillary lateral incisor and canine. Radiographic images appears like an unilocular radiolucent lesion that displaced dental teeth showing a invert pear image characteristic of the lesion. X ray and clinical examinations are important to establish the differential diagnosis of globulomaxillary cyst. The hystological examination must be send to its study and definitive diagnoses showing the presence of epithelial tissue. A clinical case of globulomaxillary cyst is presented in a 19 -year- old female patient located between canine and left first premolar maxillary region.

  18. Evaluation of radiotherapy and chemoradiotherapy for anal canal epidermoid cancer in our center

    International Nuclear Information System (INIS)

    The efficacy and safety of radiotherapy (RT) and chemoradiotherapy (CRT) for anal canal epidermoid cancer were evaluated. Twenty-four patients with anal canal epidermoid cancer were treated in our center between 1988 and 2006, consisting of 13 patients treated by RT and 11 by CRT. In these patients, the efficacy and safety of RT and CRT were evaluated in terms of adverse events, 5-year local control rates, 5-year disease-free survival rates, and 5-year survival rates. No grade 3 or higher adverse events were noted in patients receiving RT. In contrast, anorexia, diarrhea, neutropenia, and anemia were observed in 33.3%, 10%, 33.3%, and 10%, respectively, of the patients receiving CRT. The anal preserving rate, 5-year local control rate, 5-year disease-free survival rate, and 5-year survival rate were 66.7%, 73%, 77.5%, and 88.4%, respectively. RT and CRT for anal canal epidermoid cancer should be first-line treatments because of their safety and efficacy. (author)

  19. Radiosurgery of epidermoid tumors with gamma knife. Possiblity of radiosurgical nerve decompression

    International Nuclear Information System (INIS)

    Long-term results of radiosurgery for epidermoid tumors are reported. There are 7 cases including 2 males and 5 females, ages ranging from 6 to 46 (mean: 33.3 years). At radiosurgery whole tumor was covered in 4 cases and partially covered in 3 cases in attempting to relieve cranial nerve signs like trigeminal neuralgia and facial spasm. The mean maximum and marginal doses were 25.6 Gy and 14.6 Gy respectively. In the mean follow-up of 52.7 months, all the tumors showed good tumor control without any progression and tumor shrinkage has been confirmed in 2 out of the 7 cases. Symptomatic trigeminal neuralgia improved or disappeared in all 4 cases and facial spasm disappeared in one. No neurological deterioration was found in any of the cases after the treatment. In conclusion, it is apparent that epidermoid tumors do respond well to radiosurgery and the accompanying hyperactive dysfunction of cranial nerves is significantly improved by gamma knife treatment with either entire or partial tumor coverage. Therefore the radiosurgical nerve decompression for epidermoid tumor seems to be achieved by gamma-radiosurgery. (author)

  20. Isolated thoracic (D5) intramedullary epidermoid cyst without spinal dysraphism: A rare case report.

    Science.gov (United States)

    Mishra, Sudhansu Sekhar; Satapathy, Mani Charan; Deo, Rama Chandra; Tripathy, Soubhagya Ranjan; Senapati, Satya Bhusan

    2015-01-01

    Spinal epidermoid cyst, congenital or acquired, is mainly congenital associated with spinal dysraphism, rarely in isolation. Intramedullary epidermoid cysts (IECs) are rare with less than 60 cases reported so far; isolated variety (i.e., without spinal dysraphism) is still rarer. Complete microsurgical excision is the dictum of surgical treatment. A 14-year-old boy presented with 4-month history of upper backache accompanied with progressive descending paresthesia with paraparesis with early bladder and bowel involvement. His condition deteriorated rapidly making him bedridden. Neurological examination revealed upper thoracic myeloradiculopathy probably of neoplastic origin with sensory localization to D5 spinal level. Digital X-ray revealed no feature suggestive of spinal dysraphism. Contrast magnetic resonance imaging (MRI) characteristics clinched the presumptive diagnosis. Near-total microsurgical excision was done leaving behind a small part of the calcified capsule densely adhered to cord. Histopathological features were confirmative of an epidermoid cyst. Postoperatively, he improved significantly with a gain of motor power sufficient to walk without support within a span of 6 months. Spinal IECs, without any specific clinical presentation, are often diagnosed based upon intraoperative and histopathological findings, however early diagnosis is possible on complete MRI valuation. Complete microsurgical excision, resulting in cessation of clinical progression and remission of symptoms, has to be limited to sub-total or near-total excision if cyst is adherent to cord or its confines. PMID:26167216

  1. Prognostic significance of s-phase fraction detected by antithymidine antibodies in epidermoid cervix carcinomas

    International Nuclear Information System (INIS)

    Purpose: To assess the predictive value of pretreatment proliferative activity of epidermoid cervix carcinoma cells with respect to short- and long-term results of radiotherapy. Methods and Materials: The proliferative activity of 25 epidermoid cervix carcinomas was evaluated as the immunofluorescent labelling index (LI) by rabbit antithymidine antibodies reacting specifically with single-stranded DNA of replication forks in S-phase cells. The short-term clinical outcome was estimated at 3-6 months after treatment by visual and palpatory examination. Three-year follow-up data were obtained through hospital charts and correspondence with referring physicians for only 19 patients. Results: There was no statistically significant association between LI and such conventional prognostic factors as clinical stage. The LI value of cervix carcinomas was significantly associated with complete regression at 3-6 months after radiotherapy and 3-year disease-free survival. Complete regression at 3-6 months was observed in 87.5% patients with fast proliferating tumors (LI > 7.0%), and only in 41.2% patients with slowly proliferating tumors (p = 0.03). Probability of 3-year disease-free survival was 85.7% in patients with fast proliferating tumors and 50.0% in those with slowly proliferating tumors (p = 0.05). Conclusions: The immunofluorescent LI of epidermoid cervix carcinoma is able to provide prognostic information on short-term tumor response to radiotherapy and disease-free survival

  2. Isolated thoracic (D5 intramedullary epidermoid cyst without spinal dysraphism: A rare case report

    Directory of Open Access Journals (Sweden)

    Sudhansu Sekhar Mishra

    2015-01-01

    Full Text Available Spinal epidermoid cyst, congenital or acquired, is mainly congenital associated with spinal dysraphism, rarely in isolation. Intramedullary epidermoid cysts (IECs are rare with less than 60 cases reported so far; isolated variety (i.e., without spinal dysraphism is still rarer. Complete microsurgical excision is the dictum of surgical treatment. A 14-year-old boy presented with 4-month history of upper backache accompanied with progressive descending paresthesia with paraparesis with early bladder and bowel involvement. His condition deteriorated rapidly making him bedridden. Neurological examination revealed upper thoracic myeloradiculopathy probably of neoplastic origin with sensory localization to D5 spinal level. Digital X-ray revealed no feature suggestive of spinal dysraphism. Contrast magnetic resonance imaging (MRI characteristics clinched the presumptive diagnosis. Near-total microsurgical excision was done leaving behind a small part of the calcified capsule densely adhered to cord. Histopathological features were confirmative of an epidermoid cyst. Postoperatively, he improved significantly with a gain of motor power sufficient to walk without support within a span of 6 months. Spinal IECs, without any specific clinical presentation, are often diagnosed based upon intraoperative and histopathological findings, however early diagnosis is possible on complete MRI valuation. Complete microsurgical excision, resulting in cessation of clinical progression and remission of symptoms, has to be limited to sub-total or near-total excision if cyst is adherent to cord or its confines.

  3. Splenic Epidermoid Cyst during Pregnancy; Case Report and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Majid Forouzesh

    2013-10-01

    Full Text Available Cystic disease of the spleen is not frequently encountered in surgical practice. It is broadly classified as parasitic and non-parasitic, the latter being a rare entity. In this case report, an epidermoid cyst of spleen led to acute abdomen in young age pregnant woman is presented.A 26-year-old woman with 15 weeks gestational age second pregnancy referred to emergency ward with left upper quadrant pain and tenderness that ultra sonography revealed large cyst (100Ñ…110mm with internal echo in spleen in favor of hydatic cyst or abscess. The patient was managed medically for one week but developed her abdominal pain, epigastric fullness, anorexia and fever. New sonography was done for her and large cyst was detected in spleen (120Ñ…110mm. She had severe pain accompanied with anorexia and vomiting. Fetus was normal in sonography. Exploratory laprotomy with splenectomy was performed. Splenomegaly (200Ñ…130Ñ…90mm with a cyst without any adhesion and inflammation was detected. Histopathology examination showed epidermoid cyst of spleen. (140Ñ…10Ñ…90mm. Though splenic epidermoid cyst is an uncommon entity, it should be considered in the differential diagnosis of an abdominal mass in a young individual. An attempt should be made to preserve the spleen provided there is adequate parenchyma otherwise splenectomy is the rule.

  4. Occupational Causes of Testicular Cancer in Adults

    OpenAIRE

    L Fritschi; Hense, S; Dreger, S; Behrens, T.; B Mester

    2010-01-01

    Testicular cancer is one of the commonest cancers in men of working age, and is increasing in incidence in Europe and North America. One suggested mechanism of causation is that there is impaired differentiation of germ cells in the pre- or perinatal period, followed by malignant transformation in later life, possibly by a hormonal mechanism. Endocrine disrupting chemicals (EDCs) have been a major focus of interest for etiological research into testicular cancer because they interact with var...

  5. Baldness, acne and testicular germ cell tumors

    OpenAIRE

    Trabert, Britton; Sigurdson, Alice J.; Sweeney, Anne M.; Amato, Robert J.; Strom, Sara S.; McGlynn, Katherine A

    2010-01-01

    Androgen levels during critical periods of testicular development may be involved in the etiology of testicular germ cell tumors (TGCT). We evaluated the roles of adolescent and early adult life correlates of androgen exposure and TGCT in a hospital-based case control study. TGCT cases (n=187) and controls (n=148), matched on age, race and state of residence, participated in the study. Unconditional logistic regression was used to estimate associations between TGCT and male pattern baldness, ...

  6. Carcinoma epidermoide de canal anal estádio IV: complicações clínicas de doença avançada Epidermoid carcinoma of anal canal stage IV: clinical complications of advanced disease

    Directory of Open Access Journals (Sweden)

    Fernanda Bellotti Formiga

    2010-12-01

    Full Text Available O carcinoma anal é uma entidade rara que representa 4% dos tumores malignos da região anorretal, dentro os quais o carcinoma epidermoide constitui o tipo histológico mais comum. É relatado o caso de um paciente masculino, 54 anos, com carcinoma epidermoide de canal anal localmente avançado e com metástases ósseas no diagnóstico, feito após complicação infecciosa local com repercussão sistêmica. Descrevemos a evolução do paciente após o diagnóstico da neoplasia e as dificuldades de manejo clínico enconradas neste caso que são secundárias às complicações inerentes à doença de base.Anal carcinoma is a rare entity that represents 4% of anorectal malignant tumors, and the squamous cell carcinoma is the most common histological type. We report the case of 54-year-old male patient with locally advanced squamous cell carcinoma of the anal canal and metastatic bone disease at diagnosis, which was made after local infectious complications with systemic impact. We describe the evolution of the patient after the diagnosis and the difficulties of clinical management that are secondary to the complcations related to the underlying disease.

  7. Carcinoma epidermoide de canal anal estádio IV: complicações clínicas de doença avançada / Epidermoid carcinoma of anal canal stage IV: clinical complications of advanced disease

    Scientific Electronic Library Online (English)

    Fernanda Bellotti, Formiga; Alessandra Vicentini, Credidio; Daltro Lemos, Rosa; José César, Assef; Chia Bin, Fang; Peretz, Capelhuchnik; Wilmar Artur, Klug.

    2010-12-01

    Full Text Available O carcinoma anal é uma entidade rara que representa 4% dos tumores malignos da região anorretal, dentro os quais o carcinoma epidermoide constitui o tipo histológico mais comum. É relatado o caso de um paciente masculino, 54 anos, com carcinoma epidermoide de canal anal localmente avançado e com met [...] ástases ósseas no diagnóstico, feito após complicação infecciosa local com repercussão sistêmica. Descrevemos a evolução do paciente após o diagnóstico da neoplasia e as dificuldades de manejo clínico enconradas neste caso que são secundárias às complicações inerentes à doença de base. Abstract in english Anal carcinoma is a rare entity that represents 4% of anorectal malignant tumors, and the squamous cell carcinoma is the most common histological type. We report the case of 54-year-old male patient with locally advanced squamous cell carcinoma of the anal canal and metastatic bone disease at diagno [...] sis, which was made after local infectious complications with systemic impact. We describe the evolution of the patient after the diagnosis and the difficulties of clinical management that are secondary to the complcations related to the underlying disease.

  8. Aplicación de la técnica de Karapandzic en un carcinoma epidermoide del labio inferior / Application of Karapandzic Technique on Lower Lip Epidermoid Carcinoma

    Scientific Electronic Library Online (English)

    Maribel, Castillo Ramos; Ricardo, Aldana Mendoza; Victoria Cecilia, Orellana Pérez; Suleija, Estrada Domínguez; Aracelis, Viñals Legrá.

    2014-06-01

    Full Text Available En el Hospital Docente Dr. Guillermo Luís Fernández Hernández Baquero del municipio de Moa, fue atendida en enero de 2012 una paciente de 65 años de edad por presentar una lesión exofítica, infiltrante que ocupaba dos tercios del labio inferior que se extendía a piel. Se establece como impresión dia [...] gnóstica un carcinoma epidermoide y se decide el tratamiento quirúrgico. Atendiendo a las características individuales de la paciente se eligió la técnica descrita por Karapandzic, esta mantiene el pedículo vasculo-nervioso excelente, ofrece una alta frecuencia de curación y tiene resultados cosméticos-funcionales satisfactorios. Se retiró la sutura a los siete días, no se observaron complicaciones de los colgajos. Abstract in english A 65 -year- old woman showing an intense exophytic injury covering two third part of her lower lip and extended to the skin, was consulted at ?Guillermo Luis Fernández Hernández Baquero? Hospital, Moa locality, on January 31st , 2012. An epidermoid carcinoma was diagnosed and the surgical treatment [...] was determined to give. Karapandzic technique was selected according to the patient´s characteristics. This technique mainteain the vasculo-nerve pedicle in excellent conditions and provides high cure frequency and satisfactory cosmetics results. The suture was removed after seven days and no complications of the flaps were observed.

  9. Occupational Causes of Testicular Cancer in Adults

    Directory of Open Access Journals (Sweden)

    L Fritschi

    2010-09-01

    Full Text Available Testicular cancer is one of the commonest cancers in men of working age, and is increasing in incidence in Europe and North America. One suggested mechanism of causation is that there is impaired differentiation of germ cells in the pre- or perinatal period, followed by malignant transformation in later life, possibly by a hormonal mechanism. Endocrine disrupting chemicals (EDCs have been a major focus of interest for etiological research into testicular cancer because they interact with various hormonal pathways. Several EDCs including bisphenol A, phthalates, metals, polychlorinated biphenyls, and organochlorines have been investigated, but there are few studies and those that exist have not been able to assess exposure well. In addition, several studies, particularly those with better exposure assessment, have suggested that workers in electrical occupations have increased risks of testicular cancer. Electromagnetic radiation may have subthermal effects or may disrupt hormone release. Chronodisruption such as due to shift-work could potentially increase the risk of testicular cancer via disruption of hormonal cycles, but only one study has so far investigated this possibility. Lastly, solvent exposure, particularly to dimethylformamide, has been suggested to be associated with testicular cancer, but almost all these studies are based on job title only, with no specific assessment of solvent exposure. In conclusion, there is little evidence available on which to base definitive statements about occupational causes of testicular cancer. Future studies need to improve exposure assessment and develop ways to adjust for possible prenatal factors.

  10. Sarcoidose testicular: um diagnóstico a ser considerado / Testicular sarcoidosis: a diagnosis to be considered

    Scientific Electronic Library Online (English)

    Vanderlei, Real; Guilherme Locks de, Loyola; Paulo Eduardo, Zanoni; Lara Flório, Real.

    2011-04-01

    Full Text Available [...] Abstract in english Sarcoidosis is a disease of unknown etiology, characterized by the presence of noncaseating granulomas in multiple organs. We present a case of testicular sarcoidosis in a white, 55-year-old man who has come to our department complaining of bilateral testicular discomfort and weight loss. [...

  11. Testicular cancer trends as 'whistle blowers' of testicular developmental problems in populations

    DEFF Research Database (Denmark)

    Skakkebaek, N E; Rajpert-De Meyts, E; Jørgensen, N; Main, K M; Leffers, H; Andersson, A-M; Juul, A; Jensen, T K; Toppari, J

    2007-01-01

    Recently a worldwide rise in the incidence of testicular germ cell cancer (TGCC) has been repeatedly reported. The changing disease pattern may signal that other testicular problems may also be increasing. We have reviewed recent research progress, in particular evidence gathered in the Nordic...... countries, which shows strong associations between testicular cancer, undescended testis, hypospadias, poor testicular development and function, and male infertility. These studies have led us to suggest the existence of a testicular dysgenesis syndrome (TDS), of which TGCC, undescended testis, hypospadias....../disorders of sex differentiation and male fertility problems may be symptoms with varying penetration. In spite of their fetal origin, most of the TDS symptoms, including TGCC and poor semen quality, can only be diagnosed in adulthood. Data from a Danish-Finnish research collaboration strongly suggest that...

  12. Public awareness of testicular cancer and testicular self-examination in academic environments: a lost opportunity

    Directory of Open Access Journals (Sweden)

    Henry A. A. Ugboma

    2011-01-01

    Full Text Available BACKGROUND: Although testicular cancer is the most common cancer among 18- to 50-year-old males, healthcare providers seldom teach testicular self-examination techniques to clients, thus potentially missing opportunities for early detection. This form of cancer is easily diagnosable by testicular self-examination and is 96% curable if detected early. Periodic self-examination must be performed for early detection. Knowledge deficits and sociocultural norms contribute to low levels of health-related knowledge in most patients, resulting in undue delays before seeking medical advice. OBJECTIVE: Our aim is to assess the level of awareness of testicular cancer and the prevalence of the practice of testicular self-examination in academic environments to enable appropriate interventions. METHOD: A cross-sectional survey was administered to 750 consecutive males aged 18-50 years in three tertiary institutions in Port Harcourt from October 2008 to April 2009. RESULT: Knowledge or awareness of testicular cancer was poor. Almost all of the respondents were unaware that testicular lumps may be signs of cancer. A lump was typically construed as a benign carbuncle or something that could resolve spontaneously. The main factor contributing to respondents' lack of knowledge of testicular cancer was that few reported that they were "ever taught about testicular self-examination." CONCLUSION: Young adult men are unaware of their risk for testicular cancer, which is the most common neoplasm in this age group. Healthcare providers are not informing them of this risk, nor are they teaching them the simple early detection technique of self-examination of the testes.

  13. Quiste endodérmico supratentorial: caso clínico y revisión de la literatura / Supratentorial endodermal cyst: Case report

    Scientific Electronic Library Online (English)

    J.M., Garbizu; O., Mateo-Sierra; B., Iza; F., Ruiz-Juretschke; J.M., Pérez-Calvo.

    2009-08-01

    Full Text Available Los quistes endodérmicos que afectan al sistema nervioso central son lesiones expansivas muy poco frecuentes que se sitúan con mayor frecuencia a nivel espinal. Existen poco casos de localización intracraneal descritos en la literatura, la mayoría de ellos en la fosa posterior. Su etiopatogenia perm [...] anece aún desconocida. Presentamos el caso de un varón de 62 años que debuta con un cuadro de desorientación y comportamiento desinhibido tras sufrir un traumatismo craneoencefálico como consecuencia de un accidente de tráfico. En la TC craneal realizada de urgencia se objetiva una lesión quística frontal izquierda de gran tamaño con importante desplazamiento de línea media. Se punciona y evacua el contenido del quiste obteniéndose un líquido opalino rico en proteínas y elementos celulares no identificados. La RMN nos confirma los hallazgos radiológicos previos. El paciente es intervenido de forma reglada mediante craneotomía, evacuación completa del contenido y extirpación de las paredes de la lesión. El estudio anatomopatológico resulta ser compatible con el diagnóstico de quiste endodérmico. Se han descrito casos de evolución agresiva con diseminación y recidiva tras manipulación quirúrgica de la lesión; por lo tanto, el tratamiento debe consistir en la extirpación completa de la misma. Para ello será necesario realizar el diagnóstico diferencial con otras lesiones quísticas intracraneales con el fin de adecuar el tratamiento a cada caso. Abstract in english Endodermal cysts (EC) of the central nervous system are very uncommon lesions predominantly located in the spinal canal. Although rare, intracranial EC have been mainly described in the posterior fossa, with the supratentorial location considered exceptional. Apart from the low frequency of these le [...] sions, their pathoembriology still remais unknown. We report a patient with a huge frontal EC and review the literature. A 62-year-old man presented with abnormal behaviour, disorientation and decreased level of consciousness after moderate head injury. Initial cranial CT scan revealed a large cyst in the left frontal region with marked midline shift. Emergency puncture and decompression of the cyst demonstrated a milky fluid with high protein levels. Cranial MRI after patient improvement confirmed the existence of the cystic lesion with less mass effect. Delayed surgery was performed with craniotomy and total removal of the cyst. Pathological examination confirmed the presence of a typical EC. Patient made a complete recovery on follow-up with no recurrence on postoperative MRIs. Differential diagnosis of EC based on radiological data is quite difficult. As aggresive behaviour of this condition has been described following incomplete resections, the treatment of choice is a radical removal of the cyst in one or two stages depending on patient clinical condition.

  14. Choledochal cyst. A case presentation Quiste de colédoco. Presentación de un caso

    Directory of Open Access Journals (Sweden)

    Daniel Olivera Fajardo

    2012-06-01

    Full Text Available

    Congenital dilatation of the bile duct and its incidence is a rare condition reported in one in 100 000 to 150 000 newborns. Current concern about the evolution of this process is that a cholangiocarcinoma might appear. The case of a female teenager of urban origin, who attended her health area polyclinic, because of a moderate 5 months pain in her high epigastrium and in her upper right abdomen is presented. The pain appeared always after eating accompanied by vomiting and it was self-relieved. An abdominal ultrasound indicated by the patient’s family doctor showed a liver cyst. It was decided to perform an abdominal computed tomography. Through this test a cyst at the pancreatic head was found. The patient was admitted in the emergency room of the ‘’Gustavo Aldereguía Lima’’ Hospital of Cienfuegos, where she was evaluated by the physicians in the Surgery Department. It was decided to treat her surgically. Anatomopathologic results showed chronic cholecystitis, choledochal cyst and nonspecific chronic inflammation.

    La dilatación congénita de las vías biliares y su incidencia es rara, se presenta un caso cada 100 000 a 150 000 nacimientos. La preocupación actual respecto a la evolución de este proceso, es que origine un colangiocarcinoma. Se presenta el caso de una adolescente de procedencia urbana, que acudió a  cuerpo de guardia de su área de salud, refiriendo que desde hacía aproximadamente 5 meses presentaba dolor  moderado en ¨la boca¨ del estómago y en la región superior derecha del abdomen que aparecía siempre después de ingerir alimentos, se aliviaba por sí solo y se acompañaba de vómitos. Su médico de familia  indicó ultrasonido abdominal, donde se observó un quiste en el hígado. Fue  trasladada al Cuerpo de Guardia del Hospital General Universitario Dr. Gustavo Aldereguía Lima, de Cienfuegos, donde fue valorada por el Servicio de Cirugía. Se decidió la realización de  tomografÍa axial computarizada de abdomen en la que se observó un quiste a nivel de la cabeza del páncreas. Se aplicó tratamiento quirúrgico. Los resultados anatomopatológicos mostraron colecistitis crónica, quiste de colédoco e inflamación crónica inespecífica.

  15. Estudio de la fertilidad y viabilidad de quistes hidatídicos bovinos en Chile STUDY OF THE FERTILITY AND VIABILITY OF BOVINE HIDATID CYSTS IN CHILE

    OpenAIRE

    JUAN PABLO MUÑOZ; GEROLD SIEVERS

    2005-01-01

    Durante el año 1997, se muestrearon por conveniencia 4.709 bovinos de un total de 83.691 animales faenados en la Planta Faenadora de Carnes Lo Valledor, Región Metropolitana, Chile. Se registró su procedencia, sexo y categoría y en los animales positivos a hidatidosis se constató la ubicación visceral y el tamaño de los quistes. En el laboratorio se verificó la fertilidad (presencia o ausencia de protoescólices) de los quistes obtenidos y su viabilidad mediante la tinción con azul de Trypán. ...

  16. Genetics Home Reference: 46,XX testicular disorder of sex development

    Science.gov (United States)

    ... have 46,XX testicular disorder. What are the genetic changes related to 46,XX testicular disorder of ... Center . Where can I find general information about genetic conditions? The Handbook provides basic information about genetics ...

  17. Discovery – Cisplatin and The Treatment of Testicular and Other Cancers

    Science.gov (United States)

    Prior to the discovery of cisplatin in 1965, men with testicular cancer had few medical options. Now, thanks to NCI research, cisplatin and similar chemotherapy drugs are known for curing testicular and other forms of cancer.

  18. Ultrassonografia testicular em caprinos jovens da raça Alpina

    Directory of Open Access Journals (Sweden)

    L.R.B. Carazo

    2014-04-01

    Full Text Available Objetivou-se com este trabalho observar as mudanças do parênquima testicular de acordo com o fotoperíodo e com a faixa etária dos animais por meio da ecotextura testicular e a viabilidade do uso do ultrassom na avaliação testicular. Foram utilizados 4 animais desde o 6° até o 13° mês de idade. Os exames ecográficos foram realizados a cada 15 dias para avaliar a ecotextura testicular. O parênquima testicular mostrou-se moderadamente ecogênico e homogêneo. Foi observado comportamento semelhante na ecotextura testicular durante o período de avaliação, sendo maior no 8º mês de idade, quando o volume testicular também foi maior; tais mudanças foram relacionadas com o fotoperíodo da região. A avaliação ultrassonográfica dos testículos mostrou-se um método eficiente, capaz de detectar as mudanças no parênquima testicular ao longo do tempo, e como ferramenta alternativa para diferenciação de condições normais e patológicas em caprinos.

  19. Prognóstico de tumores testiculares germinativos

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    Dias Neto José Anastácio

    2002-01-01

    Full Text Available OBJETIVO: Investigar as características e a evolução de homens adultos portadores de tumores germinativos do testículo. MÉTODOS: Estudamos as características e a evolução 29 pacientes tratados (14 seminomas e 15 não seminomas. O tempo médio de seguimento foi de 56 meses para os seminomas e de 40 meses para os não seminomatosos. Todos foram submetidos a orquiectomia. Nos estádios II e III associou-se radioterapia para os seminomas, e quimioterapia e linfadenectomia para os não seminomatosos. RESULTADOS: As queixas mais freqüentes foram aumento de volume testicular (57% e dor (30%. Nos seminomas a idade média foi de 41,2 anos e nos não seminomas foi de 29,2 anos. Antecedente de criptorquidia foi assinalada em 28,5% dos seminomas e em 15,5% dos não seminomatosos. As proporções respectivas de estádios I, II e III foram de 79%, 14% e 7% em seminomas, e 40%, 27% e 33% em não seminomas. Os seminomas não provocaram elevação dos marcadores AFP ou b-HCG enquanto os não seminomatosos elevaram esses marcadores respectivamente em 46,6% e 33,3% dos casos. Morte pela doença ocorreu em 1 caso de seminoma e 3 de não seminomas, mas não houve diferença na sobrevida entre os grupos. CONCLUSÃO: A criptorquidia continua sendo um fator predisponente importante na etiologia dos tumores germinativos. Apesar dos tumores não seminomatosos se apresentarem em estádios mais avançados a sobrevida dos pacientes não difere da apresentada pelos portadores de seminomas.

  20. Quiste dentígero que causa deformación facial en un niño. Presentación de un caso

    Directory of Open Access Journals (Sweden)

    Juan Carlos Quintana Díaz

    2012-09-01

    Full Text Available Se presenta un caso interesante de un niño de 13 años que acude a la consulta de Cirugía Máxilofacial por presentar asimetría facial y bucal, además de obstrucción nasal del lado de la deformidad. Después de realizar exámenes de laboratorio y radiográficos se lleva sala de cirugía para realizar la exéresis del canino superior derecho retenido, enuclear la extensa área radiolucida a los rayos X y se reconstruye el defecto óseo residual con Hidroxiapatita en gránulos HAP-200, posteriormente se realiza estudio histopatológico. El diagnóstico definitivo corroboró el presuntivo (quiste dentígero. El paciente evolucionó de forma excelente desapareciendo la deformidad facial y los demás síntomas preoperatorios. El examen radiográfico post-operatorio mostró una excelente reconstrucción y osteo-integración del material empleado.

  1. Quiste óseo aneurismático mandibular de tipo sólido Mandibular solid aneurysmal bone cyst

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    Marta Saldaña Rodríguez

    2013-06-01

    Full Text Available El quiste óseo aneurismático sólido es una lesión ósea benigna muy infrecuente de la que no existe consenso en relación a su origen etiopatogénico. Presenta características clínicas, radiológicas e histológicas inespecíficas, por lo que los estudios ultraestructurales son fundamentales para su diagnóstico y clasificación. El diagnóstico diferencial es extenso e incluye múltiples lesiones óseas como el granuloma reparativo de células gigantes e incluso tumores malignos como el osteosarcoma. El tratamiento de elección es la cirugía conservadora. La recidiva se debe fundamentalmente a la extirpación incompleta.Solid aneurysmal bone cyst is a rare benign bone lesion for which no consensus exists regarding its origin. It has nonspecific clinical, radiological and histological features so ultrastructural studies are essential for diagnosis and classification. The differential diagnosis is extensive and includes a variety of bone lesions, such as giant cell reparative granuloma, and even malignant tumors like osteosarcoma. The treatment of choice is conservative surgery. Recurrence is due mainly to incomplete resection.

  2. CARCINOMA PAPILAR DE TIROIDES EN QUISTE DEL CONDUCTO TIROGLOSO / Thyroglossal duct cyst with papillary carcinoma

    Scientific Electronic Library Online (English)

    Patricio, Cabané T; Patricio, Gac E; Francisco, Rodríguez M; Carolina, Morales O; Juan, Aldana L; Ignacio, Boza T; Cristina, Fernández E; José, Amat V.

    2015-04-01

    Full Text Available Introducción: En alrededor de 1-2% de los casos de quiste tirogloso pueden existir cambios neoplásicos, en su mayoría corresponden a carcinoma papilar de tiroides (75-85%). El objetivo de este trabajo es presentar 9 casos de carcinoma papilar de tiroides en quiste del conducto tirogloso, en cuanto a [...] su forma de presentación y manejo. Material y Método: Se registraron en forma retrospectiva datos de pacientes con diagnóstico de carcinoma papilar de tiroides en quiste del conducto tirogloso atendidos en el Hospital Clínico de la Universidad de Chile entre 1999-2014. Resultados: De 142 casos de pacientes operados por quiste del conducto tirogloso, se registraron 9 casos de cáncer papilar (6,34%). El promedio de edad de los pacientes fue de 32 años. El diámetro promedio de la lesión fue de 4,4 cm (DS 2,2 cm). Del total, 8 pacientes fueron sometidos a tiroidectomía total, se diagnosticó cáncer de tiroides en 3 de ellos, en 6 se asoció tratamiento con radioyodo. En sólo 1 paciente se realizó una disección linfonodal. El tiempo promedio de seguimiento fue de 85 meses; a la fecha la serie no ha presentado recurrencia ni mortalidad. Conclusiones: Si bien el manejo más seguro a largo plazo es la cirugía de Sistrunk, asociado a una tiroidectomía y eventual radioyodo, la resolución quirúrgica con tiroidectomía asociada debe ser considerada cuando la morbilidad no sea mayor que el beneficio teórico. Abstract in english Introduction: In about 1-2% of cases of thyroglossal cyst may be neoplastic changes, mostly correspond to papillary thyroid carcinoma (75-85%). The aim of this paper is to present 9 cases of papillary thyroid carcinoma in thyroglossal duct cyst. Materials and Methods: Data were recorded retrospectiv [...] ely from patients diagnosed with papillary thyroid carcinoma in thyroglossal duct cyst treated at Hospital Clinico Universidad de Chile between 1999-2014. Results: From 142 cases operated for thyroglossal duct cyst, 9 cases of papillary cancer (6.34%) were recorded. The average age was 32 years. The average diameter of the lesion was 4.4 cm (SD 2.2 cm). 8 patients underwent total thyroidectomy; a simultaneous thyroid cancer was diagnosed in 3 of them. In 6 cases was added iodine therapy. In only one patient a lymph nodal dissection was performed. We do not observe any surgical complication. A solid component in preoperative ultrasonographic study is suspicious of malignancy. The average follow-up time was 85 months. There is no recurrence or mortality in this group of patients. Conclusions: Although the safest long-term management is Sistrunk surgery associated with thyroidectomy and radioiodine in selected cases, these patients must be evaluated by a multidisciplinary group and thyroidectomy should be considered in high surgical volume center, in order to minimize complications.

  3. Correlación clínico-citohistológica de los quistes congénitos cervicales / Clinical-cytohistological correlation of cervicofacial congenital cysts

    Scientific Electronic Library Online (English)

    L.D., Medina Vega; E., Márquez Rancaño; J., Concepción Guzmán; R., Rodríguez Jiménez; J., Martín Pino.

    2004-02-01

    Full Text Available Objetivo: Determinar la efectividad de los diagnósticos clínico y citológico en los quistes congénitos cervicofaciales. Método: Se realizó un estudio retrospectivo de los pacientes con diagnóstico clínico, citológico y/o histológico de quiste tirogloso, branquial y dermoide, atendidos en el Hospital [...] Universitario «Arnaldo Milián Castro», durante cinco años. Se calculó la sensibilidad, especificidad y seguridad del diagnóstico clínico y la biopsia por aspiración con aguja fina (FNAC) para cada quiste. Resultado: La seguridad del diagnóstico clínico fue de 94,1%, 92,2% y 98% para los quistes tirogloso branquial y dermoide respectivamente. Encontramos mayor tendencia al error clínico en los quistes branquiales, donde las confusiones más frecuentes se presentan con linfoadenopatías inflamatorias. La seguridad de la biopsia por aspiración con aguja fina fue de 96,1% y 94,1% para los quistes tirogloso y branquial respectivamente. Conclusiones: El diagnóstico clínico no es suficiente en ocasiones, por lo que es preciso recurrir a medios diagnósticos complementarios, como la biopsia por aspiración con aguja fina; sin embargo esta prueba no es 100% segura. Abstract in english Objective: To determine the effectiveness of clinical and cytological diagnosis in congenital cysts located in head and neck. Method: We were carried out a retrospective study of patients with clinical, cytological or histological diagnosis of thyroglossal, branchial and dermoid cyst, assisted in th [...] e University Hospital Arnaldo Milián Castro", during five years. It was calculated the sensibility, specificity and security of the clinical diagnosis and the Fine Needle Aspiration Biopsy for each cyst. Result: The security of the clinical diagnosis it was respectively of 94,1%, 92,2% and 98% for the thyroglossal, branchial and dermoid cysts. We find bigger tendency to the clinical error in branchial cysts, where the most frequent confusions are presented with inflammatory linfoadenopathy. The security of the Fine Needle Aspiration Biopsy was of 96,1% and 94,1% for the thyroglossal and branchial cysts respectively. Conclusions: Clinical diagnosis is not enough in occasions, for what is necessary to appeal to means complementary diagnoses, as the Fine Needle Aspiration Biopsy; however this test is not 100% sure.

  4. Correlación clínico-citohistológica de los quistes congénitos cervicales Clinical-cytohistological correlation of cervicofacial congenital cysts

    Directory of Open Access Journals (Sweden)

    L.D. Medina Vega

    2004-02-01

    Full Text Available Objetivo: Determinar la efectividad de los diagnósticos clínico y citológico en los quistes congénitos cervicofaciales. Método: Se realizó un estudio retrospectivo de los pacientes con diagnóstico clínico, citológico y/o histológico de quiste tirogloso, branquial y dermoide, atendidos en el Hospital Universitario «Arnaldo Milián Castro», durante cinco años. Se calculó la sensibilidad, especificidad y seguridad del diagnóstico clínico y la biopsia por aspiración con aguja fina (FNAC para cada quiste. Resultado: La seguridad del diagnóstico clínico fue de 94,1%, 92,2% y 98% para los quistes tirogloso branquial y dermoide respectivamente. Encontramos mayor tendencia al error clínico en los quistes branquiales, donde las confusiones más frecuentes se presentan con linfoadenopatías inflamatorias. La seguridad de la biopsia por aspiración con aguja fina fue de 96,1% y 94,1% para los quistes tirogloso y branquial respectivamente. Conclusiones: El diagnóstico clínico no es suficiente en ocasiones, por lo que es preciso recurrir a medios diagnósticos complementarios, como la biopsia por aspiración con aguja fina; sin embargo esta prueba no es 100% segura.Objective: To determine the effectiveness of clinical and cytological diagnosis in congenital cysts located in head and neck. Method: We were carried out a retrospective study of patients with clinical, cytological or histological diagnosis of thyroglossal, branchial and dermoid cyst, assisted in the University Hospital Arnaldo Milián Castro", during five years. It was calculated the sensibility, specificity and security of the clinical diagnosis and the Fine Needle Aspiration Biopsy for each cyst. Result: The security of the clinical diagnosis it was respectively of 94,1%, 92,2% and 98% for the thyroglossal, branchial and dermoid cysts. We find bigger tendency to the clinical error in branchial cysts, where the most frequent confusions are presented with inflammatory linfoadenopathy. The security of the Fine Needle Aspiration Biopsy was of 96,1% and 94,1% for the thyroglossal and branchial cysts respectively. Conclusions: Clinical diagnosis is not enough in occasions, for what is necessary to appeal to means complementary diagnoses, as the Fine Needle Aspiration Biopsy; however this test is not 100% sure.

  5. Quistes dermoides nasoetmoidales manejo quirúrgico Surgical management of nasoethmoidal dermoide cysts

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    Carlos Giugliano V.

    2002-07-01

    Full Text Available Los quistes dermoides nasoetmoidales son malformaciones congénitas infrecuentes, de origen ectodérmico. Clínicamente pueden presentarse como un nódulo subcutáneo y/o como un orificio fistuloso cutáneo con pelos, a cualquier nivel de la línea media nasal. A diferencia de los dermoides de otras localizaciones, existe la posibilidad de compromiso de estructuras profundas y extensión intracraneal, pudiendo asociarse a graves complicaciones, como meningitis y abscesos cerebrales. Por este motivo, los dermoides nasoetmoidales, demandan una adecuada evaluación imaginológica para planificar el abordaje quirúrgico, que permita la extirpación completa de la lesión. Por las características singulares de los quistes dermoides nasoetmoidales se consideró de interés presentar 3 casos clínicos de esta poco frecuente e interesante patología, tratados en la Unidad de Cirugía Plástica del Hospital de Niños Dr. Roberto del Río, entre los años 1999 y 2001. Se discuten posteriormente algunos aspectos relacionados con su epidemiología, etiopatogenia, evaluación y manejo quirúrgicoNasoethmoidal dermoide cysts are infrequent congenital malformations of ectodermal origin. Clinically they can present as a subcutaneous nodule and/or a cutaneous fistula with hair at whatever level in the nasal midline. Differing from dermoide cysts in other parts there exists the possibility of deep structures compromise and intracranial extension, associated ar not severe complications such as meningitis and cerebral abscesses. For this reason nasoethmoidal dermoide cysts need a meticulous radiological evaluation in order to plan surgery that allows the complete removal of the lesion. For these singular characteristics we consider it of interest to present 3 cases of this infrequent and interesting pathology, treated in the Plastic Surgery Unit in the Roberto del Río Childrens Hospital between 1999 and 2001. We discuss some aspects of epidemiology, aetiopathology and surgical evaluation and management.

  6. Giant Ovarian Cyst: a Case Report Quiste gigante de ovario: presentación de un caso

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    Mario Joel Arroyo Díaz

    2011-11-01

    Full Text Available The giant cysts ovarian growths are rare in the gynecological conditions. We present the case of a patient of 62 years of age, of white color of the skin, weight 73 kg. He came to the General Teaching Hospital "Enrique Cabrera" referring volume increase progressive on the abdomen for a year and a half of evolution without another symptom companion in its beginning, but in recent months caused her lack of air before the efforts, urinated with more frequent than usual and with a lack of appetite. He was diagnosed with cystic mass dependent on ovary, by ultrasonography and computed axial tomography. The practical laparotomy and was resected ovarian cyst left from 21 kg in weight. The anatomopathological study further reported a mucinous cystadenoma ovarian tumor Brenner associated.Los quistes gigantes de ovario son tumoraciones poco frecuentes en las afecciones ginecológicas. Se presenta el caso de una paciente de 62 años de edad, de color de piel blanca, peso 73 kg. que acudió al Hospital General Docente “Enrique Cabrera” refiriendo aumento progresivo de volumen del abdomen, de un año y medio de evolución sin otro síntoma acompañante en su comienzo, pero en los últimos meses le provocaba falta de aire ante los esfuerzos, orinaba con más frecuencia de lo acostumbrado y con falta de apetito. Se le diagnosticó una masa quística dependiente de ovario, por ultrasonografía y Tomografía Axial Computarizada. Se practicó laparotomía y se resecó quiste de ovario izquierdo de 21 kg. de peso. El estudio anatomopatológico ulterior reportó un cistoadenoma mucinoso de ovario con tumor de Brenner asociado.

  7. Amputación interescapulotorácica por cromomicosis y carcinoma epidermoide / Amputation interscapulothracique pourchr4omomycose et6 carcinome épidermoide / Interscapulothoracic amputation by chromomycosis and epidermoid carcinoma

    Scientific Electronic Library Online (English)

    Hiralio, Collazo Álvarez; Eridán, González Velázquez; Andrés G, Pardillo Morales; Stephen Yecc, Collazo Marín.

    2001-12-01

    Full Text Available Paciente del sexo masculino y blanco de 74 años de edad, con lesión dermatológica hiperpigmentada y verrucosa de más de 25 años de evolución en codo y antebrazo izquierdo; asimismo posee otra de piel en forma de coliflor y cuya evolución es reciente. Ambas presentaron diagnóstico histopatológico de [...] cromomicosis. El tratamiento inicial fue la exéresis con margen oncológico de la lesión en forma de coliflor y la electrofulguración, curetaje del resto de la lesión y tratamiento antimicótico. En un período de 5 meses el enfermo presenta evolución tórpida con toma del estado general y elefantiasis del miembro superior izquierdo hasta región supraclavicular que obliga a realizarle amputación interescapulotorácica por la técnica de Berger para mejorar la calidad de vida. El diagnóstico histopatológico de los paquetes ganglionares resecados mostró metástasis de un carcinoma epidermoide. Abstract in english The case of a 74-year-old white male patient with a hyperpigmented and verrucose dermatological injury of more than 25 years of evolution in his left elbow and forearm is reported. He also has another cauliflower-like skin injury of recent evolution. Both presented histopathological diagnosis of chr [...] omomycosis. The initial treatment was exeresis with oncological margin of the cauliflower-like injury and electrofulguration, curettage of the rest of the injury and antimycotic treatment. In 5 months, the patient had a torpid evolution with taking of the general state and elephantiasis of the upper left extremity to the supraclavicular region that led to the interscapulothoracic amputation by Berger’s technique to improve his quality of life. The histopathological diagnosis of the resected ganglionar packages showed metastasis of an epidermoid carcinoma.

  8. Segmental testicular infarction following cysto-prostatectomy

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    Alleemudder Adam

    2011-01-01

    Full Text Available Segmental (partial testicular infarction is a very rare condition of unknown cause in more than 70% of cases. Several predisposing conditions have been described, but to our knowledge, this is the first documented case and often overlooked complication occurring as a result of cysto-prostatectomy. It usually presents in an acute manner resembling testicular torsion or epididymo-orchitis and is confirmed using ultrasonography. In some cases, it may present insidiously with no pain and may be confused with a testicular tumor due to the hypo-echoic features on imaging. In unclear situations, Doppler sonography shows vascularity and a magnetic resonance scan can be useful to distinguish between the two conditions.

  9. Characteristic findings of metrizamide CT cisternography in an epidermoid in the posterior fossa

    International Nuclear Information System (INIS)

    A case of epidermoid cyst in the posterior fossa showing a characteristic finding upon metrizamide CT cisternography is reported. A 42-year-old man was admitted with gait disturbance. The abnormal signs were trunucal ataxia, gait ataxia, left cerebellar sign and nystagmus. A CT scan revealed a large, low-density area and the fourth ventricle could not be seen clearly. Absorption values were in the range of 5 - 18 Hounsfield units. There was no change in the absorption values of the lesion following intravenous injection of contrast medium. Metrizamide CT cisternography was performed No remarkable change was seen 1 hour after intrathecal injection of metrizamide. However, metrizamide irregularly surrounded the left margin of the low-density area 3 hours after intrathecal injection. Moreover, metrizamide stained the area heterogeneously like a honeycomb or sponge at 6 hours. Finally, only a small amount of metrizamide remained in this area after 24 hours. Suboccipital craniectomy revealed a pearly tumor in the cisterna magna, wrapped in a thin white capsule and partially adherent to the cerebellomedullary junction. The tumor was totally removed. Histopathological investigation showed stratified squamous epithelium with keratinous material. A honeycomb- or sponge-like image seems to be a characteristic finding in metrizamide CT cisternography of the epidermoid cyst. This finding has not been previously reported. However, pneumoencephalographical findings in some cases of epidermoid were reported as crumb- or sponge-like images. These images were thought to be caused by air covering the surface of the pearly tumor. These images should be similar to the one found in the present study using CT cisternography. (author)

  10. Splenic Epidermoid Cyst during Pregnancy; Case Report and Review of the Literature

    OpenAIRE

    Majid Forouzesh; Laleh Ghanbarzadegan; Masoomeh Rahimi; Leila Ghahramani

    2013-01-01

    Cystic disease of the spleen is not frequently encountered in surgical practice. It is broadly classified as parasitic and non-parasitic, the latter being a rare entity. In this case report, an epidermoid cyst of spleen led to acute abdomen in young age pregnant woman is presented.A 26-year-old woman with 15 weeks gestational age second pregnancy referred to emergency ward with left upper quadrant pain and tenderness that ultra sonography revealed large cyst (100?110mm) with internal echo in ...

  11. Urgent penectomy in a patient presenting with epidermoid carcinoma of the penis associated to myiasis

    OpenAIRE

    Antonio J. Tavares; Rodrigo Barros; Favorito, Luciano A.

    2007-01-01

    The objective of this study is to describe the case of a patient presenting advanced epidermoid carcinoma of the penis associated to myiasis. A 41-year-old patient presenting with a necrotic lesion of the distal third of the penis infested with myiasis was attended in the emergency room of our hospital and was submitted to an urgent penectomy. This is the first case of penile cancer associated to myiasis described in the literature. This case reinforces the need for educative campaigns to red...

  12. Urgent penectomy in a patient presenting with epidermoid carcinoma of the penis associated to myiasis

    Directory of Open Access Journals (Sweden)

    Antonio J. Tavares

    2007-08-01

    Full Text Available The objective of this study is to describe the case of a patient presenting advanced epidermoid carcinoma of the penis associated to myiasis. A 41-year-old patient presenting with a necrotic lesion of the distal third of the penis infested with myiasis was attended in the emergency room of our hospital and was submitted to an urgent penectomy. This is the first case of penile cancer associated to myiasis described in the literature. This case reinforces the need for educative campaigns to reduce the incidence of this disease in developing countries.

  13. Combined regional chemotherapy and radiation therapy in the treatment of epidermoid carcinoma in the oro-facial region

    International Nuclear Information System (INIS)

    Treatment was studied of oro-facial epidermoid carcinoma by combined chemo- and radiotherapy and eventual surgery. Cytostatic drugs were applied intraarterially. After a monocytostatic treatment trial with Methotrexate (MTX), a combined cytostatic program was developed alternating two cytostatic drugs, viz., MTX and Bleomycin (BLM). The usefulness of chemotherapy and its inclusion in the treatment of epidermoid carcinoma in the oro-facial region was found justified for combined therapy. The selected intraarterial administration, however, is not suitable for routine application. For this reason, the combination irradiation or surgical therapy with chemotherapy was adopted. (author)

  14. Esplenomegalia gigante por quiste esplénico: Presentación de un caso / Giant splenomegaly due to splenic tumor: A case presentation

    Scientific Electronic Library Online (English)

    Janet, Domínguez Cordovés; Julio, Díaz Mesa; Glenis, Madrigal Batista; Simeón, Collera Rodríguez; Ramiro, Torres Core; Rocío, Queral Gómez Quintero; Gaspar, Alcalde Mustelier.

    2006-06-01

    Full Text Available Los quistes del bazo como causa de esplenomegalia son extremadamente raros pero no excepcionales. Dentro de ellos los secundarios o seudoquistes son los más frecuentes y más informados en la literatura. Sus formas de presentación son muy variables y oscilan entre dolor abdominal intenso y presentaci [...] ón asintomática. El tratamiento también es muy controversial y varía desde técnicas mínimamente invasivas hasta la esplenectomía total. En nuestro centro ingresó una paciente con el diagnóstico de tumor retroperitoneal, que una vez estudiado resultó ser un quiste esplénico. El objetivo de este trabajo es exponer todos los elementos concernientes a esta paciente, a fin de dar a conocer los estudios, hallazgos quirúrgicos y resultados anatomopatológicos

  15. Grayscale and color Doppler features of testicular lymphoma.

    Science.gov (United States)

    Bertolotto, Michele; Derchi, Lorenzo E; Secil, Mustafa; Dogra, Vikram; Sidhu, Paul S; Clements, Richard; Freeman, Simon; Grenier, Nicolas; Mannelli, Lorenzo; Ramchandani, Parvati; Cicero, Calogero; Abete, Luca; Bussani, Rossana; Rocher, Laurence; Spencer, John; Tsili, Athina; Valentino, Massimo; Pavlica, Pietro

    2015-06-01

    Pooled data from 16 radiology centers were retrospectively analyzed to seek patients with pathologically proven testicular lymphoma and grayscale and color Doppler images available for review. Forty-three cases were found: 36 (84%) primary and 7 (16%) secondary testicular lymphoma. With unilateral primary lymphoma, involvement was unifocal (n = 10), multifocal (n = 11), or diffuse (n = 11). Synchronous bilateral involvement occurred in 6 patients. Color Doppler sonography showed normal testicular vessels within the tumor in 31 of 43 lymphomas (72%). Testicular lymphoma infiltrates through the tubules, preserving the normal vascular architecture of the testis. Depiction of normal testicular vessels crossing the lesion is a useful adjunctive diagnostic criterion. PMID:26014335

  16. Dopplex Sonographic Evaluation of Variococele–Related Testicular Atrophy

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    A. Shakeri Bavil

    2007-10-01

    Full Text Available Introduction & Objective: Varicocele is often mentioned as a common cause of testicular atrophy. The aim of this study was to evaluate varicocele-related testicular atrophy with Duplex sonography.Materials & Methods: Seventeen patients with testicular atrophy due to varicocele were included into the study.Results: Echogenisity of the atrophic testis was homogeneous. Mean peak systolic velocities (PSV in intratesticular arteries for atrophic and normal testes were 5.57±2.03 cm/s and 6.49 ± 1.37 cm/s, respectively. The difference was not significant (P > 0.05.Conclusion: Varicocele-related testicular atrophy is not associated with testicular parenchymal heterogeneity, and does not affect the intra-testicular and testicular arterial PSV.

  17. Ictus isquémico mesencefálico aislado secundario a ruptura de quiste dermoide / Isolated mesencephalic stroke related to a ruptured intracranial dermoid cyst

    Scientific Electronic Library Online (English)

    J.M., Ramírez-Moreno; M., Ortega-Martínez; M.A., Fernández-Gil; L.M., Bernal-García; V., Bejarano-Moguel; I., Fernández-Portales; M.J., Gómez-Baquero; J.M., Cabezudo-Artero.

    2009-06-01

    Full Text Available Los quistes dermoides son lesiones benignas de origen embrionario que representan del 0.04 a 0,25% de todos los tumores intracraneales. Estos quistes ocasionalmente pueden romperse diseminándose el contenido graso intraquístico al espacio subaracnoideo y/o los ventrículos laterales. En este caso pue [...] de provocar diversas manifestaciones clínicas de forma aguda o retardada. El debut de este tipo de tumor con un ictus agudo está escasamente reflejado en la literatura. Presentamos el caso de una mujer de 26 años con un infarto mesencefálico aislado secundario a la ruptura de un quiste dermoide. Discutimos el mecanismo fisiopatológico supuesto y realizamos una revisión de los casos recogidos en la literatura. Abstract in english Dermoids cysts are embrionary benign lesions that comprise approximately 0.04-0.25% of all intracranial tumors. Occasionally they break and spread their content into subarachnoid space and/or lateral ventricles causing several acute or delayed symptoms. Debut of this type of tumor as acute stroke is [...] poorly reflected in literature. We present a 26-year-old woman with a isolated mesencephalic infarct secondary to spontaneous rupture of a dermoid cyst. We discuss the possible pathophysiological mechanisms for this condition and review the literature.

  18. Quistes del rafe medio del pene. Presentación de dos casos / Penile medial raphe cysts. Presentation of two cases

    Scientific Electronic Library Online (English)

    Niurka, García Sosa; Francisco J, Fong Aldama.

    2014-08-01

    Full Text Available Los quistes del rafe medio del pene son lesiones benignas, infrecuentes en urología pediátrica, y usualmente asintomáticos. Se localizan en la región parameatal y borde inferior del prepucio. Se presentaron dos casos que acudieron a consulta de Urología, por el hallazgo del quiste por parte de los p [...] adres de los pacientes. Ambos quisten tenían de 1 a 2 cm de diámetro. Ninguno de los casos reportados se les había realizado la circuncisión previamente. A los dos casos se les hizo la marsupialización del quiste mediante cirugía ambulatoria, siendo la evolución post operatoria satisfactoria. Abstract in english Penile medial raphe cysts are benign lesions, infrequent in pediatric urology, usually asymptomatic. They are located in the parameatal region and the low edge of the foreskin. We presented two cases assisting to the Urology consultation because the patients´ parents discovered the cysts. Both cysts [...] were 1- 2cm diameter. No one of the patients was previously circumcised. It was carried out the marsupialization of both cysts in ambulatory surgery, being satisfactory post-surgery evolution.

  19. Quiste broncogénico de la pared torácica: Caso clínico y revisión de la literatura Bronchogenic cyst in the chest wall

    Directory of Open Access Journals (Sweden)

    David Schnettler R.

    2003-09-01

    Full Text Available Los quistes broncogénicos se ubican en la mayoría de los casos en la cavidad torácica, en relación con el árbol bronquial, en la periferia del parénquima pulmonar o en el mediastino. Sin embargo, existen casos infrecuentes en que el quiste se localiza en la pared torácica, principalmente en el tejido celular subcutáneo presternal, en la región cervical y el abdomen. Se postula que la ubicación fuera de la cavidad torácica ocurre por migración, o pinzamiento del tejido pulmonar normal durante la fusión de los procesos esternales o diafragmáticos. En este artículo, se presenta como caso clínico, un paciente 10 años de edad, de sexo masculino, que presentó una lesión nodular presternal, confirmada como quiste broncogénico en el estudio histológico. Se revisa la literatura al respecto y se discute el enfoque diagnóstico y terapéutico más adecuado a esta patologíaThe majority of bronchogenic cysts are found in the thoracic cavity, principally the bronchial tree, the peripheral lung parenchyma or the mediastinum. However, infrequently the cysts are found in the thoracic wall, mainly in the presternal subcutaneous tissues, the cervical region or the abdomen. It is postulated that cysts found outside the thoracic cavity occur by migration or by entrapment of normal pulmonary tissue during the embryonic fusion of the sternum or diaphragm. We present a case of a 10 year old boy who presented with a nodular presternal lesion, histologically confirmed as a brochogenic cyst. We review the literature and discuss the diagnosis and most adequate treatment

  20. Long-term effects of prepubertal testicular vessel ligation on testicular function in the rat.

    Science.gov (United States)

    Pascual, J A; Villanueva-Meyer, J; Rutgers, J L; Lemmi, C A; Sikka, S C; Ehrlich, R M; Mena, I; Rajfer, J

    1990-08-01

    To determine the effects of unilateral testicular vein and artery ligation in the immature rat on the function and final location of the testis at adulthood, 10-day-old male rats underwent either a sham operation or unilateral ligation of these vessels of the still undescended testis. Testicular location, blood flow, size and histology as well as ventral prostate weights were measured 50 days later at adulthood. At age 60 days, it was determined that all testes were descended into the scrotum, and there were no differences in testis and ventral prostate weights, intratesticular sperm counts and mean seminiferous tubular area between the control and sham operated animals. However, there was an 18% reduction in testicular blood flow (ml. per 100 gm. per minute +/- standard error of mean) in the operated animals when compared to the sham (20.43 +/- 1.10 versus 16.69 +/- 0.74, p less than 0.02). These data indicate that although there is a slight but significant reduction in testicular blood flow at adulthood when the testicular artery and vein are ligated early in life, this diminution is not sufficient to alter the ultimate location, testicular weight and spermatogenic function of the testis. This would suggest that after ligation of the main testicular vessels to the immature testis, the collateral blood supply is able to compensate with time to allow normal growth and development of the testis. These experimental observations provide additional support for the 2-staged approach to the high undescended testis whereby the testicular vessels are initially ligated and a subsequent procedure is performed to place the undescended testis into the scrotum. PMID:2374222

  1. Testis Sparing Surgery For Epidermoid Cyst of Testis in an Infertile Man

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    Parlakta?, B., S.

    2005-01-01

    Full Text Available In this case report, testis sparing surgery, performed for a heterogenous testicular mass in a 25 year-old man was presented. The patient was infertile for five years. Preoperative ultrasound findings allowed us to such surgery. Intraoperative frozen sectioning showed the benign nature of the lesion, consistent with the final histologic examination. For aesthetic, cosmetic, psychologic and fertility preserving benefits, treatment selection of testis sparing surgery in some testicular masses should be carried out according to clinical, radiological and frozen section findings.

  2. FGF2 mediates DNA repair in epidermoid carcinoma cells exposed to ionizing radiation

    International Nuclear Information System (INIS)

    Fibroblast growth factor 2 (FGF2) is a well-known survival factor. However, its role in DNA repair is poorly documented. The present study was designed to investigate in epidermoid carcinoma cells the potential role of FGF2 in DNA repair. The side population (SP) with cancer stem cell-like properties and the main population (MP) were isolated from human A431 squamous carcinoma cells. Radiation-induced DNA damage and repair were assessed using the alkaline comet assay. FGF2 expression was quantified by enzyme linked immunosorbent assay (ELISA). SP cells exhibited rapid repair of radiation induced DNA damage and a high constitutive level of nuclear FGF2. Blocking FGF2 signaling abrogated the rapid DNA repair. In contrast, in MP cells, a slower repair of damage was associated with low basal expression of FGF2. Moreover, the addition of exogenous FGF2 accelerated DNA repair in MP cells. When irradiated, SP cells secreted FGF2, whereas MP cells did not. FGF2 was found to mediate DNA repair in epidermoid carcinoma cells. We postulate that carcinoma stem cells would be intrinsically primed to rapidly repair DNA damage by a high constitutive level of nuclear FGF2. In contrast, the main population with a low FGF2 content exhibits a lower repair rate which can be increased by exogenous FGF2. (authors)

  3. Surgical treatment of testicular germinative tumors

    International Nuclear Information System (INIS)

    A critical appraisal of the role of surgery in the strategy of management of patients with germ cell testicular cancer is presented. Special interest is directed to treatment of the primary tumor and the importance of surgery after chemotherapy in patients with advanced disease. A critical discussion on the role of retroperitoneal lymphadenectomy in patients with nonseminomatous tumors is presented. (author)

  4. The Correlation between Ultrasound Testicular Volume and Conventional Semen Parameters in Albanian Subfertile Males

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    Adrian Kristo

    2014-09-01

    CONCLUSION: Testicular volume has a direct correlation with semen parameters and the critical total testicular volume indicating normal testicular function is approximately 26.6 ml (the mean testicular volume 13.3 ml. The measurement of testicular volume can be helpful for assessing fertility at the initial physical examination.

  5. Carcinoma epidermoide de la conjuntiva, su posible asociación con el papilomavirus humano Epidermoid carcinoma of the conjunctiva, its possible association with human papillomavirus

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    María de los Ángeles Rios Hernández

    2004-08-01

    Full Text Available El carcinoma epidermoide de células escamosas de la conjuntiva ocupa el segundo lugar en frecuencia de los tumores malignos oculares. Este tumor puede tener una evolución letal si no es diagnosticado y tratado en etapas tempranas. Recientes reportes de la literatura, muestran la presencia del papilomavirus humano 16 (PVH 16 en displasias epiteliales conjuntivales y carcinoma escamoso, este virus puede desempeñar un papel importante en el desarrollo de lesiones benignas y malignas de la conjuntiva. Sin embargo, la información es escasa y contradictoria, por lo que es interés nuestro estudiar un grupo de ellas. Se determinó la presencia de los PVH 16 y 18 por la técnica de PCR, se halló la presencia de los tipos 16 (66,6 % y 18 (66,6 % en lesiones premalignas mientras que en las malignas fue del 50 % para el tipo 16 y del 25 % para el tipo 18. Se demostró la existencia de infección viral por papiloma en lesiones de la conjuntiva, con una mayor carga viral en las lesiones premalignas lo que pudiera ser un factor necesario para la transformación maligna en esta localización.The epidermoid squamous cell carcinoma of the conjunctiva occupies the second place in frequency among the occular malignant tumors. This tumor may have a lethal evolution if it is not diagnosed and treated early. Recent reports of literature show the presence of human papillomavirus 16 (HPV in conjunctival epithelial displasias and squamous cell carcinoma. This virus may play an important role in the development of bening and malignant lesions of the conjunctiva. However, the information is scarce and contradictory and that´s why we are interested in studying a group of them. The presence of HPV16 and 18 was determined by using the PCR technique. Types 16 (66.6 % and 18 (66.6 % were found in premalignant lesions, whereas 50% of type 16 and 25 % of type 18 were observed in malignant lesions. It was proved the existance of viral infection due to papilloma in conjunctiva lesions, with a higher viral burden in the premalignant lesions, which may be a necessary factor for the malignant transformation in this localization.

  6. Quiste tirogloso con granuloma de colesterol en una escolar simulando carcinoma de tiroides

    Scientific Electronic Library Online (English)

    Maryori, García; Enrique, Marquina; Carmen, Fuenmayor; María Fernanda, Marquina; Eduardo, Marquina; Carlos, Marquina; Anna, García; Astrid, Cantor.

    2013-10-01

    Full Text Available Objetivo: Presentar el caso de una escolar con quiste tirogloso y granuloma de colesterol, hallazgo inusual que simuló clínica e imagenológicamente un carcinoma de tiroides. Esta asociación es infrecuente y hay pocos casos reportados. Caso clínico: Escolar femenina de 11 años, quién consultó por pre [...] sentar disfagia y tumoración en región anterolateral izquierda del cuello, de 3x3 cm, de consistencia dura, dolorosa a la palpación, sin signos de flogosis. Ultrasonido de cuello evidenció conducto tirogloso permeable en la línea media con presencia de nódulo hipoecoico, de bordes bien definidos, sin calcificaciones que medía 1,8 x 0,9 cm. Se extirpó la tumoración que medía 3x2, 5x0, 8cm. y se observó cavidad quística de 0,8 cm. de diámetro mayor que contenía material de aspecto gelatinoso. Por debajo de éste, se observó nódulo bien circunscrito de 1,5 cm. de diámetro mayor, constituido por tejido firme de color blanco-amarillento. El estudio histopatológico reveló un quiste revestido por epitelio cilíndrico y respuesta inflamatoria linfohistiocitaria, con células gigantes tipo “cuerpo extraño” alrededor de hendiduras; que correspondían a d dd epósito de colesterol. Conclusión: Se presenta este caso por su rareza y porque puede confundirse clínica e imagenológicamente con una neoplasia maligna. Asimismo, pudiera corresponder al primer caso reportado en nuestro país. Abstract in english Objective: We report the case of a 11 year- old girl with thyroglossal cyst and cholesterol granuloma, an unusual finding that clinically simulates thyroid carcinoma. This association is unusual and there are few reported cases worldwide. Case report: An 11-year-old girl consulted for dysphagia and [...] a 3 x 3 cm hard mass. The mass was painful on palpation and was located in the anterolateral neck left. It was phlogosis-free. A neck ultrasound showed a 1.8 x 0.9 cm permeable midline thyroglossal conduct with a hypoechoic nodule with well-defined edges but without calcifications. A 3 x 2,5 x 0, 8cm tumor was removed. A 0.8 cm cystic cavity that contained gelatinous material was observed. Below that cavity, a well-circumscribed nodule was observed. It measured 1.5 cm and was made up of firm yellowish tissue. The histopathology examination revealed a cyst lined with columnar epithelium and inflammatory linfohistiocitic response with foreign body type giant cells around cracks that corresponded to a cholesterol deposit. Conclusion: We present this case because it is very unusual and because it can be clinically and radiologically mistaken for a malignant tumor. It could be the first case ever reported in Venezuela.

  7. Presentación inusual de un quiste dentigero en paciente pediatrico: Reporte de un caso y revisión de la literaturaRomero Yulis, Jiménez Cecilia. Hernández

    Scientific Electronic Library Online (English)

    Patricia, Alexis Ganai.

    Full Text Available El quiste dentígero es el quiste Odontogénico mas frecuente, generalmente se presenta rodeando la corona de un diente impactado, afecta a los caninos superiores y terceros molares inferiores, con mayor predilección en el sexo masculino, entre la segunda y tercera década de la vida . A continuación s [...] e presenta un caso clínico de un quiste dentígero mandibular inusual por presentar aspecto clínico y radiográfico de Osteomielitis crónica con osteítis proliferativa (Osteomielitis de Garré), en un paciente femenino de 7 años de edad con una evolución de 2 meses, Así mismo se describe la conducta clínica que se tomó con respecto al caso para llegar al diagnóstico definitivo. Abstract in english The denture quiste it is the most frequent to surround the tooth, it affect the upper caninos and third below molars, the most affected is the male sex, between the second and third decade of life. It is showed a clinic case of a dental jaw quiste with an unusual apparience that suggest a Garre’s Os [...] teomyelitis cronic in a 7 year female patient, with an evolution of two months. Patient was subject to clinical, radiography and hystopatology test to confirm the final diagnostics of the lesion, and its described the clinical approachment in order to become the definitive diagnosis.

  8. Tumor testicular bilateral "quemado" ("burn out") / Burn out bilateral testicular tumor

    Scientific Electronic Library Online (English)

    M.J., Mola Arizo; V., Gonzalvo Pérez; M.D., Torregrosa Maicas; J.A., Navarro Antón; A., Gómez-Ferrer Lozano; A., Estany Pérez; A.C., Polo Peris.

    2005-03-01

    Full Text Available Es difícil diferenciar entre tumor de células germinales retroperitoneal primario y enfermedad metastásica de un tumor gonadal indetectado o que ha regresado espontáneamente. Presentamos un caso clínico de "burn out" o tumor quemado, es decir un tumor retroperitoneal seminomatoso, metastásico con im [...] portantes alteraciones testiculares bilaterales tanto ecográficas como anatomopatológicas, pero sin evidenciar tumor. Pese a las controversias que detallamos, nuestra opción terapéutica fue la extirpación de la masa residual tras la quimioterapia asociada a orquiectomía bilateral en el mismo acto. Concluimos que ante un tumor retroperitoneal, la existencia de alteraciones ecográficas en los testículos, pese a una palpación normal, debe hacer pensar en un "Síndrome de burn out", siendo obligatoria la biopsia testicular bilateral. La exploración quirúrgica de los mismos e incluso la orquiectomía son opciones a valorar en función de cada paciente. Abstract in english Differentiating a primary retroperitoneal seminoma from a metastatic testicular tumor with an occult testicular primary or a burned out testicular cancer remains difficult. We present a case of a burned out tumor. The patient had a retroperitoneal seminoma with ultrasonically and pathologically demo [...] nstrated abnormalities in both testes, but without evidence of tumor. The patient received chemotherapy and underwent surgery of the residual retroperitoneal mass and bilateral orchiectomy. All surgical specimens were negative for testis cancer. Conclusion: Primary extragonadal germ cell tumors in the retroperitoneum are a rare entity. The presence of a retroperitoneal tumor with ultrasonographical abnormalities in testicular evaluation should be considered as a metastases of a burned out testicular cancer, and biopsy is mandatory. Surgical evaluation and orchiectomy should be evaluated in a individual setting.

  9. Prognostic role of p53 protein expression in epidermoid carcinoma of the anal canal

    International Nuclear Information System (INIS)

    Purpose: To assess the prognostic significance of p53 protein expression in patients with primary epidermoid carcinoma of the anal canal managed by radiation therapy (XRT), 5-fluorouracil (5-FU), and mitomycin C (MMC). Methods and Materials: From January 1991 to December 1993, 58 consecutive patients with primary epidermoid carcinoma of the anal canal were treated in a prospectively designed protocol of XRT (24 Gy/12--3((1)/(2)) wk split--28 Gy/14) and concurrent 5-FU (1000 mg/m2/day 1-4) and MMC (10 mg/m2 day 1) of each cycle of XRT. Paraffin-embedded tumor samples were unavailable in 9 patients, leaving 49 patients in the study. Expression of p53 protein was studied using immunohistochemistry and quantified as percent tumor nuclei showing positive staining. Actuarial survival and disease-free survival (DFS) rates were estimated by the Kaplan-Meier method, and compared using the log-rank test. A Cox proportional hazard model was used for the multivariable analysis. Results: There were 6 T1, 26 T2, 7 T3, and 10 T4 lesions. Primary tumor sizes ranged from 1-15 cm with a median of 4 cm. There were 6 patients with nodal metastases. Median follow-up was 4.5 years. Positive nuclear immunostaining for p53 was observed in 40 of 49 patients. The median percent positive staining was 5%, with 13, 9, and 18 patients showing staining in <5%, 5 to <10%, and 10-50% of tumor nuclei respectively. There was no correlation of percent p53 staining with gender, age, tumor stage, size, or histology. Local, regional, and distant failures were observed in 12, 2, and 2 patients respectively. The 5-yr survival and DFS were 84% and 64% respectively. In univariate analysis, the only prognostic variable for survival was gender. For DFS, advanced T category and large tumor size were predictive of poor DFS. In multivariate analysis, poor DFS was associated with high T category (p = 0.0008), basaloid histology (p = 0.001), male gender (p = 0.002), and increasing percent of p53 protein expression (p 0.01). Conclusions: It is concluded that expression for p53 protein is present in a high percentage of patients with epidermoid carcinoma of the anal canal. For patients managed with combined XRT, 5-FU, and MMC, percent p53 protein expression is of prognostic value for DFS independent of other clinical factors such as T category, gender, and histology

  10. Tumores dermóides e epidermóides intra-espinhas / Intraspinal epidermoid and dermoid tumours

    Scientific Electronic Library Online (English)

    Oscar, Fontenelle Filho; Francisco, Duarte.

    1971-03-01

    Full Text Available São relatados dois casos de tumores epidermóides e um de tumor dermóide, todos intrarraquianos. Este último era de localização epidural ao nível da coluna torácica (caso 3); os dois tumores epidermóides situavam-se na coluna tóraco-lombar (caso 1) e lombar (caso 2), respectivamente, sendo o primeiro [...] intramedular e o segundo intradural. Em dois casos (casos 2 e 3) os tumores associavam-se a fístula dérmica congênita. Um paciente (caso 3) foi operado aos dois meses de idade; a descoberta do tumor deveu-se à realização da raquimanometria que revelou bloqueio, apesar do paciente não apresentar qualquer sinal neurológico de compressão medular. Os autores são de opinião que, em presença de fístula dérmica congênita ao nível da coluna vertebral, principalmente quando localizada acima do segmento lombosacro, deve-se sempre suspeitar da possibilidade do tumor epidermóide ou dermóide intrarraquiano, mesmo na ausência de sinais neurológicos. A combinação de sintomas neurológicos de longa duração, a evidência radiológica de erosão e alargamento do canal raquiano e a história de fístula dérmica congênita proporcionaram o diagnóstico pré-operatório correto no caso 2. Abstract in english Two cases of epidermoids and one case of dermoid intraspinal tumours are reported. The last case was located at thoracic level (T7) (case 3) and was epidural in localization. The two epidermoids tumours were located at the thoracic-lumbar (case 1) and lumbar (case 2) level, respectively; the first w [...] as intramedullary and the second subdural in localization. In two (cases 2 and 3) there was associated communicating pilonidal sinuses. One of the patients (case 3) was operated within the second month of age. The early discovery of the tumour in this patient was made through a lumbar raquimanometry that disclosed a complete subarachnoid block. In spite of this the patient did not presented any neurological symptoms. The authors are of opinion that in presence of a dermal fistula higher to lumbo-sacral spinal segment one must have in mind the possibility of intraspinal epidermoid or dermoid tumour, even in absence of neurological symptoms. The combination of long term clinical symptoms, radiographic evidence of pressure erosion, enlargement of the spinal canal and pilonidal sinus led to the correct preoperative diagnosis in case 2.

  11. Hidatidosis retroperitoneal secundaria a quiste hidatídico de localización hepática / Retroperitoneal hydatidosis secondary to hepatic hydatid cyst

    Scientific Electronic Library Online (English)

    Katherina A, Vizcaychipi; Sonia, Sosa; Federico, Camicia; Graciela, Santillán; María, Casalins; María del Carmen, Nigro.

    2012-12-01

    Full Text Available La hidatidosis es una enfermedad de distribución mundial, producida por un platelminto parásito del género Echinococcus. El caso que se presenta corresponde a una paciente con una tumoración fluctuante en el espacio retroperitoneal lumbar, secundaria a un quiste hepático. El diagnóstico inicial de c [...] erteza fue dado por el hallazgo de ganchos rostelares de protoescólices en el líquido aspirado de un absceso. Este trabajo describe el cuadro clínico, el diagnóstico y el tratamiento médico-quirúrgico de esta paciente. Se analiza cómo la elaboración de un diagnóstico certero requiere de un análisis adecuado de los antecedentes epidemiológicos, las manifestaciones clínicas, los estudios de imágenes y las pruebas de laboratorio, ya que el conjunto de estos datos confirman el caso. Abstract in english Hydatid disease in a worldwide zoonosis. It is caused by a parasitic platyhelminth of the genus Echinococcus. We present a patient with a fluctuating lumbar tumor in the retroperitoneal space, secondary to a hepatic cyst. The initial diagnosis was made by identification of rostellar hooks from proto [...] scoleces in the fluid aspirated from the abscess. We herein describe the clinical manifestations, diagnosis and medical and surgical treatment of this unusual case and conclude that the development of an accurate diagnosis required a proper analysis of the patient's epidemiological history, clinical manifestations, imaging studies and laboratory tests. A multidisciplinary approach and differential diagnosis is paramount to be able to establish a cause of the disease to deliver appropriate treatment.

  12. Hidatidosis retroperitoneal secundaria a quiste hidatídico de localización hepática Retroperitoneal hydatidosis secondary to hepatic hydatid cyst

    Directory of Open Access Journals (Sweden)

    Katherina A Vizcaychipi

    2012-12-01

    Full Text Available La hidatidosis es una enfermedad de distribución mundial, producida por un platelminto parásito del género Echinococcus. El caso que se presenta corresponde a una paciente con una tumoración fluctuante en el espacio retroperitoneal lumbar, secundaria a un quiste hepático. El diagnóstico inicial de certeza fue dado por el hallazgo de ganchos rostelares de protoescólices en el líquido aspirado de un absceso. Este trabajo describe el cuadro clínico, el diagnóstico y el tratamiento médico-quirúrgico de esta paciente. Se analiza cómo la elaboración de un diagnóstico certero requiere de un análisis adecuado de los antecedentes epidemiológicos, las manifestaciones clínicas, los estudios de imágenes y las pruebas de laboratorio, ya que el conjunto de estos datos confirman el caso.Hydatid disease in a worldwide zoonosis. It is caused by a parasitic platyhelminth of the genus Echinococcus. We present a patient with a fluctuating lumbar tumor in the retroperitoneal space, secondary to a hepatic cyst. The initial diagnosis was made by identification of rostellar hooks from protoscoleces in the fluid aspirated from the abscess. We herein describe the clinical manifestations, diagnosis and medical and surgical treatment of this unusual case and conclude that the development of an accurate diagnosis required a proper analysis of the patient's epidemiological history, clinical manifestations, imaging studies and laboratory tests. A multidisciplinary approach and differential diagnosis is paramount to be able to establish a cause of the disease to deliver appropriate treatment.

  13. Lymphoepithelial Cyst in Jugal Mucosa / Quiste Linfoepitelial en la Mucosa Yugal

    Scientific Electronic Library Online (English)

    Marceli Moço, Silva; Alvimar Lima de, Castro; Ana Maria Pires, Soubhia; Marcelo Macedo, Crivelini.

    2011-04-01

    Full Text Available Un quiste linfoepitelial bucal es raro, con pocos casos reportados en la literatura. El objetivo de este artículo es describir un caso clínico, centrándose en los aspectos clínicos y diagnósticos, tratamiento y pronóstico. La lesión tuvo un año de evolución, y se había desarrollado como un nódulo fi [...] broso en la mucosa yugal de un paciente de 71 años de edad con leucoderma. Teniendo en cuenta la hiperplasia fibrosa inflamatoria, fibroma y mucocele como diagnósticos diferenciales, se llevó a cabo una biopsia por escisión. Una cavidad quística limitada por epitelio pseudoestratificado sin proyecciones en el tejido conjuntivo, con tejido linfoide en el interior fue identificado microscópicamente. No se observaron eventos adversos postoperatorios, y el seguimiento clínico al año confirmó el pronóstico favorable de este tipo de lesión. Abstract in english Mouth lymphoepithelial cyst is rare, with few cases reported in literature. The aim of this article is to describe a clinical case, focusing on clinical and diagnostic aspects, treatment and prognosis. The lesion was one year old and had developed as a fibrous nodule in the jugal mucosa of a 71-year [...] -old leucoderma patient. Considering focal inflammatory fibrous hyperplasia, fibroma and mucocele as differential diagnosis, excisional biopsy was carried out. A cystic cavity limited by pseudostratified epithelium without projections into the conjunctive tissue, with lymphoid tissue within, was microscopically identified. Without postoperative adverse events, the one-year clinical followup confirmed the favorable prognosis of this kind of lesion.

  14. Quiste cervical como manifestación inicial de un microcarcinoma papilar de tiroides

    Scientific Electronic Library Online (English)

    Jorge, Fallas González; Rodolfo, Guzmán Cervantes; Carlos, Valverde Monge; Maritza, Valdés Gutiérrez.

    2012-03-01

    Full Text Available Las masas quísticas en cuello son usualmente benignas en pacientes jóvenes. Sin embargo, tumores malignos de la cabeza y el cuello pueden presentarse ocasionalmente con metástasis quísticas. Se presenta el caso de una paciente de 33 años asintomática con una masa cervical quística de gran tamaño con [...] 1 año de evolución, que inicialmente fue manejada como un quiste branquial, en quien luego de estudios por imagen e histopatológicos se sospechó carcinoma papilar de tiroides. Este diagnóstico fue corroborado en el trans-operatorio y se trató con tiroidectomía total, disección ganglionar del compartimiento central y disección ganglionar radical modificada derecha. El diagnóstico definitivo en el espécimen quirúrgico fue de un microcarcinoma papilar de tiroides con metástasis ganglionares quísticas y posteriormente la paciente recibió terapia con yodo radioactivo Abstract in english Cystic cervical masses are usually benign in the young adult population. However malignant tumors of the head and neck may present ocasionally as cystic metastasis. Herein we report a case of a 33 year old female patient, asymptomatic, with a huge cystic cervical mass of 1 year data. The initial dia [...] gnosis was a branchial clef cyst, but after imaging studies and histopathologic examination papillary thyroid carcinoma was suspected. This diagnosis was confirmed in an intraoperatory consultation, so a total thyroidectomy, central lymph node dissection and modified radical neck dissection was performed. The final diagnosis on the surgical specimen was a papillary microcarcinoma of the thyroid with cystic lymph node metastasis and the patient received radioactive iodine afterwards

  15. Cáncer primario de tiroides en un quiste tirogloso / Primary thyroid cancer in a thyroglossal duct cyst

    Scientific Electronic Library Online (English)

    Carlos Eber, González.

    2008-06-01

    Full Text Available La patología quirúrgica congénita del cuello representa un tópico importante en el ejercicio de la cirugía en la población pediátrica. No obstante, un porcentaje no despreciable de pacientes adultos puede presentar estas alteraciones y las lesiones quísticas congénitas de la línea media del cuello, [...] específicamente las relacionadas con trastornos del desarrollo embriológico de la glándula tiroides, representan una de las patologías más frecuentes. Se presenta un caso de cáncer papilar de tiroides originado en un quiste del conducto tirogloso, en una mujer de edad adulta, una complicación por demás infrecuente, con muy pocos casos reportados en la literatura médica. Se discute su diagnóstico y manejo, basados en la revisión del tema. Abstract in english Surgical pathology of the neck constitutes an important field in pediatric surgery. Nevertheless, a significant number of adult patients may present neck pathology, and cervical midline cystic congenital lesions, specifically those related with abnormal embryologic development of the thyroid gland, [...] represent the most frequent type of abnormality. We report a case of papillary carcinoma originating in a thyroglossal duct cyst in an adult woman; very few cases have been reported in the lityerature. We discuss diagnosis and management, and include a literature review.

  16. Cáncer primario de tiroides en un quiste tirogloso Primary thyroid cancer in a thyroglossal duct cyst

    Directory of Open Access Journals (Sweden)

    Carlos Eber González

    2008-06-01

    Full Text Available La patología quirúrgica congénita del cuello representa un tópico importante en el ejercicio de la cirugía en la población pediátrica. No obstante, un porcentaje no despreciable de pacientes adultos puede presentar estas alteraciones y las lesiones quísticas congénitas de la línea media del cuello, específicamente las relacionadas con trastornos del desarrollo embriológico de la glándula tiroides, representan una de las patologías más frecuentes. Se presenta un caso de cáncer papilar de tiroides originado en un quiste del conducto tirogloso, en una mujer de edad adulta, una complicación por demás infrecuente, con muy pocos casos reportados en la literatura médica. Se discute su diagnóstico y manejo, basados en la revisión del tema.Surgical pathology of the neck constitutes an important field in pediatric surgery. Nevertheless, a significant number of adult patients may present neck pathology, and cervical midline cystic congenital lesions, specifically those related with abnormal embryologic development of the thyroid gland, represent the most frequent type of abnormality. We report a case of papillary carcinoma originating in a thyroglossal duct cyst in an adult woman; very few cases have been reported in the lityerature. We discuss diagnosis and management, and include a literature review.

  17. Quiste óseo aneurismático mandibular de tipo sólido / Mandibular solid aneurysmal bone cyst

    Scientific Electronic Library Online (English)

    Marta, Saldaña Rodríguez; Maria Fe, García Reija; Belén, García-Montesinos Perea; Marta, Mayorga Fernández; Ramón Carlos, Saiz Bustillo.

    2013-06-01

    Full Text Available El quiste óseo aneurismático sólido es una lesión ósea benigna muy infrecuente de la que no existe consenso en relación a su origen etiopatogénico. Presenta características clínicas, radiológicas e histológicas inespecíficas, por lo que los estudios ultraestructurales son fundamentales para su diagn [...] óstico y clasificación. El diagnóstico diferencial es extenso e incluye múltiples lesiones óseas como el granuloma reparativo de células gigantes e incluso tumores malignos como el osteosarcoma. El tratamiento de elección es la cirugía conservadora. La recidiva se debe fundamentalmente a la extirpación incompleta. Abstract in english Solid aneurysmal bone cyst is a rare benign bone lesion for which no consensus exists regarding its origin. It has nonspecific clinical, radiological and histological features so ultrastructural studies are essential for diagnosis and classification. The differential diagnosis is extensive and inclu [...] des a variety of bone lesions, such as giant cell reparative granuloma, and even malignant tumors like osteosarcoma. The treatment of choice is conservative surgery. Recurrence is due mainly to incomplete resection.

  18. Quiste tímico cervical en un niño / Cervical thymic cyst in a child

    Scientific Electronic Library Online (English)

    Lissette, Nápoles Oconor; Jaime, Gonzálvez Bertot; Erich Roberto, Ramón Nuñez; Manuel, Carrazana Araujo; Orlando, Reyes Jay.

    2014-12-01

    Full Text Available Se presenta el caso clínico de un paciente de 7 años de edad con antecedentes de buena salud, quien fue ingresado a los 5 años en el Hospital Infantil Sur de Santiago de Cuba por presentar aumento de volumen en la región lateral izquierda del cuello, doloroso, sobre todo al ingerir alimentos, y fieb [...] re de 38 °C. Luego del tratamiento indicado egresó a los 10 días, pero con seguimiento por consulta externa. Al cabo de los 2 años y medio acudió a la consulta de Cirugía con aumento de volumen en la región lateral derecha del cuello. Se realizó la exéresis del tumor y los resultados del estudio anatomopatológico confirmaron que se trataba de un quiste tímico cervical Abstract in english The case report of a 7 years patient is presented with a history of good health who was admitted when he was 5 years in the Southern Pediatric Hospital from Santiago de Cuba for presenting increase of volume mainly in the left lateral region of the painful neck, when ingesting foods, and fever 38 °C [...] . After the prescribed treatment he was discharged 10 days later, but with follow up through out-patient department. After 2 and a half years he came to the Surgery Department with an increase of volume in the right lateral region of the neck. The exeresis of the tumor was carried out and the results of the pathological study confirmed that it was a thymic cervical cyst

  19. Quiste vítreo: a propósito de un caso / Vitreous cyst: a case presentation

    Scientific Electronic Library Online (English)

    J.P., Moreno-Arrones; R., Jiménez-Parras.

    2012-01-01

    Full Text Available Caso clínico: Presentamos el caso de un paciente de 12 años que refiere miodesopsias en ojo izquierdo (OI) de 6 meses de evolución. Presenta una agudeza visual (AV) de 1/0,9, en fondo de ojo izquierdo un quiste vítreo anterior. En la resonancia magnética se observa una imagen hipointensa en T1 y en [...] la ecografía en modo B una lesión hipoecoica de 3,2x4,3mm; la biomicroscopia ultrasónica puso de manifiesto un cuerpo ciliar normal. Conclusión: Dada la buena AV del paciente se observará periódicamente. Si interfiriese con el eje visual es posible fragmentarlo con láser Nd:YAG o argón, o bien su extracción vía pars plana. Abstract in english Case report: We report a case of a 12-year-old patient who complained about visual disturbances in left eye for 6 months. His visual acuity was 1/0.9, funduscopy in left eye revealed a free-floating cyst in the anterior vitreous. Magnetic resonance showed a low intense image in T1, and B-scan ultras [...] ound confirmed a hypoechogenic cyst of 3.2x4.3mm; ultrasound biomicroscopy revealed a normal ciliary body. Conclusion: Given the good VA the patient will be monitored periodically. If the cyst interferes with visual axis, management with Nd:YAG or Argon laser photocystotomy or remove it by pars plana vitrectomy has been advocated.

  20. Neonatal outcome and congenital malformations in children born after ICSI with testicular or epididymal sperm

    DEFF Research Database (Denmark)

    Fedder, J; Loft, A; Parner, Erik Thorlund; Rasmussen, S; Pinborg, A

    2013-01-01

    Does neonatal outcome including congenital malformations in children born after ICSI with epididymal and testicular sperm [testicular sperm extraction (TESE)/percutaneous epididymal sperm aspiration (PESA)/testicular sperm aspiration (TESA) (TPT)] differ from neonatal outcome in children born after...

  1. Testicular sperm retrieval at the time of bilateral radical orchiectomy

    Directory of Open Access Journals (Sweden)

    Nassir Anmar

    2009-01-01

    Full Text Available A new indication for testicular tissue cryopreservation is discussed here. We evaluate the feasibility of testicular sperm extraction during bilateral orchiectomy for testicular cancer. A 26-year-old man with a history of right orchidopexy presented with primary infertility. Tests revealed left varicocele and oligospermia. He underwent varicocelectomy but was lost to follow-up. Nine months later, he presented with right-sided solid testicular swelling. Ultrasound examination confirmed the finding of possible neoplasm and revealed contralateral intratesticular lesion. Since the patient turned azoospermic, no semen sample could be cryopreserved. Permanent histopathological sections revealed bilateral classical seminomas. On processing the fresh healthy looking specimen, normal-looking viable sperm were obtained. Future attempts at in-vitro fertilization with intracytoplasmic sperm injection should be possible. This method has been described in metachronous testicular cancer, but to our knowledge, we are the first to use it in synchronous bilateral testicular tumors.

  2. Testicular cancer trends as 'whistle blowers' of testicular developmental problems in populations

    DEFF Research Database (Denmark)

    Skakkebaek, N E; Rajpert-De Meyts, E

    2007-01-01

    Recently a worldwide rise in the incidence of testicular germ cell cancer (TGCC) has been repeatedly reported. The changing disease pattern may signal that other testicular problems may also be increasing. We have reviewed recent research progress, in particular evidence gathered in the Nordic countries, which shows strong associations between testicular cancer, undescended testis, hypospadias, poor testicular development and function, and male infertility. These studies have led us to suggest the existence of a testicular dysgenesis syndrome (TDS), of which TGCC, undescended testis, hypospadias/disorders of sex differentiation and male fertility problems may be symptoms with varying penetration. In spite of their fetal origin, most of the TDS symptoms, including TGCC and poor semen quality, can only be diagnosed in adulthood. Data from a Danish-Finnish research collaboration strongly suggest that trends in TGCC rates of a population may be 'whistle blowers' of other reproductive health problems. As cancer registries are often of excellent quality - in contrast to registries for congenital abnormalities - health authorities should consider an increase in TGCC as a warning that other reproductive health problems may also be rising.

  3. Linfoma no Hodgkin testicular con compromiso de tejidos blandos

    OpenAIRE

    Bernal. P.; Duarte M.; Ucros. G.

    2008-01-01

    El compromiso testicular por linfoma es una manifestación extranodal de la enfermedad, manifestación inicial de una enfermedad nodal oculta o manifestación tardía de linfoma nodal diseminado. Corresponde al 5% de todos los tumores testiculares y es la neoplasia mas común del testículo en los pacientes mayores de 50 anos. [1]., sin embargo el linfoma primario de testículo es extremadamente raro [5]. corresponde al 1% de los LNH [3]. La mayoría de los linfomas testiculares son LNH B difuso de c...

  4. Testicular Parameters and Morphological Characteristics of Testicular and Epididymal Spermatozoa of White Fulani Bulls in Nigeria Parámetros Testiculares y Características Morfológicas de los Espermatozoides Testicular y Epididimal de Toros Fulani Blancos en Nigeria

    OpenAIRE

    Matthew Olugbenga Oyeyemi; Temilade Babalola Eunice

    2006-01-01

    Testicular parameters and morphological characteristics of testicular and epididymal spermatozoa of white Fulani bulls were study using twenty testicles. The objective was to study the normal testicular parameter and morphological changes during epididymal transit in the epididymis of white Fulani bulls. It was observed that there was reduction in the proportion of spermatozoa carrying the proximal cytoplasmic droplet (PCD) along the epididymis as spermatozoa mature. There were more narrow he...

  5. Bilateral and synchronic seminomatous testicular neoplasia

    Scientific Electronic Library Online (English)

    Ademar, Schmitz.

    2003-08-01

    Full Text Available Testicular neoplasia is rare, especially when it is bilateral, and even more when it is synchronic, with its incidence being only 0.17% of germinative tumors of testicles. We present here the case of a male, 32-year old patient, without children. Patient underwent a bilateral radical orchiectomy, fo [...] llowing previous sperm harvest, in a sperm bank. Surgery was performed in 2 stages, with a 12-day interval, with implantation of a silicone testicular prosthesis. The result of anatomicopathological examination revealed bilateral classical seminoma, pT2 on the right side andT1 on the left. He was submitted to bilateral complementary radiotherapy, with 2,500 cGy on each side. Patient had a good outcome from a medical and oncologic perspective, but a follow-up with psychotherapy was needed.

  6. La linfadenectomía retroperitoneal para el cáncer testicular

    Directory of Open Access Journals (Sweden)

    Jaime Gutiérrez-Góngora

    2001-03-01

    Full Text Available Históricamente, los pacientes diagnosticados con enfermedad neoplásica testicular B (II han sido tratados con una disección primaria de ganglios retroperitoneales con la opción de aplicar quimioterapia adyuvante. Recientemente, varios autores han optado por la quimioterapia como tratamiento primario con la linfadenectomía retroperitoneal reservada para los pacientes que no lograban una remisión completa después del tratamiento con quimioterapia. El objetivo de este trabajo es definir por qué la linfadenectomía retroperitoneal (LR es realizada siempre en el Servicio de Urología del Hospital San Juan de Dios en el tratamiento del cáncer testicular de células germinales no seminomatosas estadio clínico A (I y B (II. Se presenta el sustento científico que avala esta práctica y se hace una breve reseña del estadiaje, del procedimiento quirúrgico utilizado.

  7. [Relationship between phthalates and testicular dysgenesis syndrome].

    Science.gov (United States)

    Chen, Guo-Rong; Dong, Lei; Ge, Ren-Shan; Hardy, Matthew P

    2007-03-01

    Recent epidemiological evidence demonstrates that boys born to women exposed to phthalates during pregnancy have an increased incidence of cryptorchidism, hypospadias, testicular cancer and spermatogenic dysfunction, which are collectively referred to as testicular dysgenesis syndrome (TDS). TDS may be attributed to the dysfunction of Leydig cells and Sertoli cells during their differentiation after exposure to phthalates in utero. Fox example, Leydig cell functions are significantly affected by phthalates, leading to the decrease of two Leydig cell products--insulin-like growth factor 3 (INSL3) and testosterone, which are critical factors for testis descent. The disorientation of Leydig cells and Sertoli cells in the adult testis may be the cause of spermatogenic dysfunction. PMID:17393778

  8. Testicular Compromise due to Inguinal Hernia

    OpenAIRE

    Morgan Eutermoser; Kristen Nordenholz

    2012-01-01

    A 34-year-old male presented to the emergency department with a 3-hour complaint of pain in the rightlower quadrant and right testicle. He stated that his pain began suddenly while standing at work. Onphysical examination, he had a small, firm, unreducible bulge in his right inguinal canal and an enlargedright scrotum. The patient was placed in trendelenburg position; intravenous fentanyl, valium, anddilaudid were administered; and surgery consult was obtained. A testicular ultrasonogram (Fig...

  9. Testicular tumors - clinical aspects and therapy

    International Nuclear Information System (INIS)

    In this study the author reports about classification, clinical experience, therapy and therapeutic results of testicular tumors on the basis of results given in literature and of own investigations performed at the Clinic and Policlinic for Radiotherapy at Wuerzburg. In total, 97 patients with testicular tumors were examined and their cases analysed. These patients had received radiotherapy between January 1, 1962 and December 31, 1979. The difficulties with the intended classification of testicular tumors and the advantages and disadvantages of the individual nomenclatures are described. Consideration of the affected age-groups showed that this disease concerns mainly younger males with a high life expectancy. The study depicts the relatively discrete symptoms and signs and the difficulties connected with clinical diagnosis. A more generous indication for the exposition of the testicles is demanded. Also the lymphatic drainage of the testicular region, the resulting paths of metastatic spread and the difficulties connected with the lymphographic detection of metastases are described. There are three therapeutic measures: surgical intervention, radiotherapy and cytostatic treatment. With seminomas mandatory semitestectomy and radiotherapy will suffice; with other affections than seminomas, semitestectomy shall be followed by a combined therapy comprising removal of lymphatic nodes and cytostatic treatment and not so much radiotherapy. The results of treatment given in literature are compared with the own results. This comparison revealed good success with treatment of seminomas. With non-seminomal affections exclusive radiotherapy appears to be insufficient. Therefore a combined therapy is postulated, which must be rendered possible by a good interdisciplinary cooperation of pathologists, urologists and radiologists. (orig.)

  10. Echogenic mass as a sign of testicular torsion

    International Nuclear Information System (INIS)

    In most cases of testicular torsion the patient presents an anatomic predisposition due to a congenital abnormality of the tunica vaginalis, the so-called bell and clapper malformation. We present six cases of testicular torsion in which ultrasound disclosed the presence of a grossly lobular, extra testicular, echogenic mass. At surgery, it was found to coincide with the morphological changes exhibited by torsion of mediastinum testis and spermatic cord. Th knowledge of the nature of this image prevents its erroneous interpretation and its being confused with other structures such as enlarged epididymis testicular appendages, scrotal hernia, etc. (Author) 17 refs

  11. Testicular descent: INSL3, testosterone, genes and the intrauterine milieu

    DEFF Research Database (Denmark)

    Bay, Katrine; Main, Katharina M; Toppari, Jorma; Skakkebæk, Niels E

    2011-01-01

    Complete testicular descent is a sign of, and a prerequisite for, normal testicular function in adult life. The process of testis descent is dependent on gubernacular growth and reorganization, which is regulated by the Leydig cell hormones insulin-like peptide 3 (INSL3) and testosterone. Investi......Complete testicular descent is a sign of, and a prerequisite for, normal testicular function in adult life. The process of testis descent is dependent on gubernacular growth and reorganization, which is regulated by the Leydig cell hormones insulin-like peptide 3 (INSL3) and testosterone...

  12. Interstitial brachytherapy in the treatment of oropharyngeal epidermoid carcinomas (256 pts)

    International Nuclear Information System (INIS)

    Purpose: the objective of this study is to report the results of interstitial brachytherapy [BT] used as exclusive treatment or as a boost in a large series of velo-tonsillar or glosso-tonsillar epidermoid carcinomas. Materials and methods: from 1982 to 1995, 256 patients (230 men and 26 women; average age: 60 years), with oropharyngeal epidermoid cancer as described above have been treated with 192 Iridium LDR interstitial BT: 218 primary tumors [PT] (39 T1, 103 T2, 74 T3, 2 T4) and 38 second primary tumors [SPT] developed in previously irradiated area (24 T1, 8 T2, 6 T3). Most of these lesions were ulcerated or infiltrating (79%). Treatment of PT associated external beam irradiation (mean dose: 52 Gy) and interstitial BT (15 to 25 Gy) with the plastic tube technique (1 to 4 radio - active wires). Lymphatic areas have been treated by exclusive irradiation, radical neck dissection and irradiation, or with irradiation followed by lymphadenectomy. SPT have been treated with BT alone (50 to 75 Gy; 25 case) or with external beam irradiation (30 to 50 Gy) and BT (15 to 40 Gy; 13 cases). No treatment has been performed for lymphatic areas (all patients NO). Results: Local control rate is similar for PT (84%) and for SPT (76%): 90 and 89% respectively for tonsillar tumors, 80 and 73% for palatin arch and 83 and 80% for glosso-tonsillar sulcus. The rate of grade 2 and 3 delayed toxicity is 10% for PT and 14% for SPT. The 3 years survival rates are respectively 71% for primary tumors and 46% for second primaries. Discussion: when compared with external beam RT, BT allows a local control rate increase of 10 to 25% with low complication rates. Salvage surgery morbidity is not increased and salivary function is partially preserved with improvement of quality of life

  13. Testicular Histomorphometric Evaluation of Zebu Bull Breeds

    Directory of Open Access Journals (Sweden)

    Paulo Antônio Terrabuio Andreussi

    2014-12-01

    Full Text Available The objective of this study was to evaluate the quantitative histology and testicular biometrics in zebu bulls of different breeds. Testicular fragments of Nelore (n=10, Polled Nelore (n=6, Gir (n=5, Guzerat (n=5 and Tabapuã bulls (n=5 were used. The fragments were perfusion-fixed in Karnovsky solution, embedded in glycol methacrylate and stained with toluidine blue-1% sodium borate. The Nelore animals had a higher tubular volumetric proportion (85.2% and greater height of the seminiferous epithelium (73.2 µm than the Gir, Guzerat and Tabapuã breeds. The Nelore animals also had a higher volumetric proportion of Leydig cells (5.2% than the Guzerat and Tabapuã breeds. There was no significant difference for any of these parameters between the Nelore and Polled Nelore breeds. The gonadosomatic index, seminiferous tubule diameter, cross-sectional area of the seminiferous tubule and tubule length (total length and length per gram of testicular parenchyma did not vary among the breeds studied. The morphometric parameters evaluated suggested that the genetic selection applied to the Nelore and Polled Nelore breeds improved the efficiency of spermatogenesis in these breeders.

  14. Doppler sonographic findings in testicular microlithiasis

    Directory of Open Access Journals (Sweden)

    Selim Serter

    2008-08-01

    Full Text Available OBJECTIVE: The aim of this prospective study was to compare the resistive index (RI values, which is a parameter of testicular parenchymal perfusion, in testicular microlithiasis (TM cases and normal cases. MATERIALS AND METHODS: 2179 volunteers, all healthy men (17-42 years of age from the Annual Army Reserve Officer Training Corps training camp were included in the study. A screening scrotal ultrasound was performed and all men diagnosed with TM underwent a scrotal Doppler ultrasonography scan (US. US examinations were performed for subjects with TM and without TM as a control group and RI was determined. RESULTS: 53 men with TM were identified in the 2179 US. Spectral Doppler examination was applied to 50 randomly selected cases (100 testicles without TM and 92 testicles with TM, 39 cases (78 testicles with bilateral and 14 cases with unilateral involvement. However, 48 normal testicles (17 bilateral and 14 unilateral and 47 testicles with TM (15 bilateral and 17 unilateral, 10 of which were cases with bilateral TM where flow from the centripetal artery could be obtained and analyzed were included in the statistical analysis for resistive indices. There was no significant difference regarding the RI and spectral examinations between subjects with and without TM. An interesting finding was the twinkling artifact observed in three cases. CONCLUSION: Microliths did not alter the RI values and thus had no influence on testicular perfusion on Doppler US examination.

  15. Comet assay on mice testicular cells

    Directory of Open Access Journals (Sweden)

    Anoop Kumar Sharma

    2015-05-01

    Full Text Available Heritable mutations may result in a variety of adverse outcomes including genetic disease in the offspring. In recent years the focus on germ cell mutagenicity has increased and the “Globally Harmonized System of Classification and Labelling of Chemicals (GHS” has published classification criteria for germ cell mutagens (Speit et al., 2009. The in vivo Comet assay is considered a useful tool for investigating germ cell genotoxicity. In the present study DNA strand breaks in testicular cells of mice were investigated. Different classes of chemicals were tested in order to evaluate the sensitivity of the comet assay in testicular cells. The chemicals included environmentally relevant substances such as Bisphenol A, PFOS and Tetrabrombisphenol A. Statistical power calculations will be presented to aid in the design of future Comet assay studies on testicular cells. Power curves were provided with different fold changes in % tail DNA, different number of cells scored and different number of gels (Hansen et al., 2014. An example is shown in Figure 1. A high throughput version of the Comet assay was used. Samples were scored with a fully automatic comet assay scoring system that provided faster scoring of randomly selected cells.

  16. Combination of radiotherapy and cetuximab for patients suffering from of an advanced and non operable epidermoid carcinoma of the ORL sphere: results and side effects

    International Nuclear Information System (INIS)

    The authors report a retrospective survey of a set of locally advanced epidermoid carcinomas treated by irradiation and cetuximab. They assessed the response to the treatment, the specific survival, and the global survival as well as the tolerance. The survey is based on 31 men and 5 women suffering from different stage 4 non-metastatic advanced epidermoid carcinomas of the ORL sphere. Short communication

  17. Colloidal cyst of the third ventricle. Case presentation Quiste coloide del tercer ventrículo. Presentación de un caso

    Directory of Open Access Journals (Sweden)

    Joan O Rojas Fuentes

    2009-09-01

    Full Text Available

    Colloidal cysts are congenital intracranial benign lesions of the anterior superior portion of the third ventricle. They represent between the 0,2 and 2 % of all the intracranial tumours and represent the 15 or 20 % of all the intraventricular masses. They become symptomatic during the adolescence or early adulthood and start normally with migraine or symptoms of intracranial hypertension causing obstructive hydrocephaly. We present the case of a teenager of 18 years of age with history of migraine after two years and the symptoms worsened in intensity and frequency including vomiting and bilateral paresthesia; the diagnosis was obstructive hydrocephaly with colloidal cyst of the third ventricle. An appropriate practice was adopted due to the uncertain diagnosis in order to avoid neurological damage and death. We discussed the main characteristics of the colloidal cyst, its clinical presentation and radiological characteristics and we performed.

    Los quistes coloides son lesiones intracraneales congénitas benignas, de la porción antero-superior del tercer ventrículo. Suponen del 0,2 al 2 % de todos los tumores intracraneales y representan del 15 al 20 % de todas las masas intraventriculares. Comienzan a ser sintomáticos en la adolescencia o edad adulta temprana, generalmente con manifestaciones de cefalea o síntomas de hipertensión intracraneal al provocar hidrocefalia obstructiva. Se presenta una adolescente de 18 años con historia de cefalea de 2 años de evolución, cuyos síntomas fueron empeorando en intensidad y frecuencia, acompañados de vómitos y parestesias bilaterales; se le diagnosticó hidrocefalia obstructiva con quiste coloide del tercer ventrículo. Ante la sospecha del diagnóstico se tomó una conducta adecuada, para evitar el deterioro neurológico y la muerte. Se discutieron las principales características del quiste coloide, su cuadro clínico y radiológico.

  18. Variaciones anatómicas bilaterales de vasos renales y testiculares / Bilateral anatomical variations of renal and testicular vessels

    Scientific Electronic Library Online (English)

    HUMBERTO, FERREIRA ARQUEZ.

    2014-12-01

    Full Text Available Normalmente las arterias testiculares surgen de la aorta abdominal, aunque hay reportes acerca de variaciones en su origen. También es un hallazgo común dos arterias renales (derecha e izquierda) derivadas de la aorta abdominal que suministran irrigación al respectivo riñón de cada lado, y actualmen [...] te la literatura reporta gran variabilidad en el número de arterias renales. Durante una disección de rutina en un cadáver masculino de 65 años de edad se encontraron múltiples variaciones anatómicas bilaterales de vasos testiculares y renales. Las variaciones encontradas fueron: presencia bilateral de tres arterias renales y tres venas renales, vena renal izquierda retro-aórtica, terminación de la vena frénica inferior izquierda en la vena renal izquierda, doble arteria testicular izquierda y doble arteria testicular derecha, todas originándose desde arterias renales accesorias. Las variaciones descritas aquí son únicas, no conocidas, ya que es el primer caso reportado hasta ahora en la literatura disponible y proporcionan una información significativa a radiólogos, endocrinólogos, especialistas en fertilidad, urólogos y cirujanos, en la determinación de la viabilidad de intervenciones quirúrgicas libres de complicación en esta región, así como el manejo postoperatorio Abstract in english Testicular arteries normally arise from the abdominal aorta. There are reports about of variations in the origin. It is also a common finding two (right and left) derived renal arteries of the abdominal aorta to the respective supplying irrigation kidney from each side, current literature report gre [...] at variability in the number of renal arteries. Multiple anatomical variations bilateral of testicular vessels and renal were found during routine dissection in a 65-year-old male cadaver. The variations found were: bilateral presence of three renal arteries and three renal veins, left renal vein retro-aortic, termination of the left inferior phrenic vein into the left renal vein, double left testicular artery and double right testicular artery all originating from accessory renal arteries. The variations described here are unique is not known since it is the first case reported so far in the available literature and provide significant informations to radiologists, endocrinologists, fertility specialists, urologists and surgeons, in determining the feasibility of complication-free surgical interventions in this region as well as the post-operative management

  19. Tumor desmoide mesentérico simulando una recidiva de cáncer testicular / Mesenteric desmoid tumor mimicking a testicular cancer recurrence

    Scientific Electronic Library Online (English)

    Francisco Javier, Pérez García; Jesús, Pinto Blazquez; Juan Javier, Rodríguez Martínez; Ricardo, Gutiérrez García; José Ignacio, Jorge Barreiro; Julio, Velasco Alonso.

    2007-08-01

    Full Text Available Objetivo: Presentar un caso de un tumor desmoide en un paciente tratado de un seminoma testicular que simulaba una recidiva del tumor testicular. Método: Presentamos el caso de un paciente de 41 años, tratado de un seminoma testicular 26 meses antes, mediante extirpación de una masa testicular retro [...] peritoneal y quimioterapia, que presenta en el seguimiento, una masa abdominal mesentérica que se etiquetó clínicamente de recidiva de seminoma. Resultado: Histológicamente se informa de tumor desmoide mesentérico. Se hace diagnóstico diferencial con un tumor de estroma gastrointestinal mediante el estudio inmunohistoquímico. Conclusiones: El tumor desmoide es un tumor raro. Se han descrito pocos casos en pacientes afectos previamente de tumor testicular. Debe incluirse en el diagnóstico diferencial de las recidivas por tumor testicular. Abstract in english Objective: Report of one case of desmoid tumor in a patient who had been treated of a testicular seminoma 26 months before, with excision of a retroperitoneal mass and chemotherapy. On follow-up he presented with a mesenteric abdominal mass which was clinically labeleled as a recurrence of the semin [...] oma. Results: Histologically it was reported as a mesenteric desmoid tumor. Differential diagnosis with gastrointestinal stromal tumor was performed with immunohistochemical studies. Conclusions: Desmoid tumor is rare. There are few cases reported in patients with history of previous testicular tumor. It should be included in the differential diagnosis of testicular tumor recurrences.

  20. Synchronous thyroid and colon metastases from epidermoid carcinoma of the lung: case report / Metástases sincrônicas de carcinoma epidermoide de pulmão em tireoide e cólon: relato de caso

    Scientific Electronic Library Online (English)

    Carla Rameri Alexandre Silva de, Azevedo; Loureno, Cezana; Eduardo Sampaio Patrício de, Moraes; Maria Dirley Ferreira de Souza, Begnami; Tadeu Ferreira, Paiva Júnior; Aldo Lourenço Abbade, Dettino; Marcello Ferretti, Fanelli.

    2010-12-01

    Full Text Available CONTEXTO: O câncer de pulmão de células não pequenas evolui, na maioria dos casos, com metástases a distância. Ossos, sistema nervoso central, glândula adrenal e fígado são os sítios mais frequentes de metástases. Disseminação para pele, miocárdio, tireoide e intestino pode ocorrer, entretanto é rar [...] a. RELATO DE CASO: Descrevemos um caso de carcinoma espinocelular (CEC) de pulmão com metástase em cólon e tireoide, em mulher de 66 anos. A lesão era irressecável, e foi iniciada quimioterapia. A paciente evoluiu com suboclusão intestinal e a colonoscopia evidenciou pólipo colônico cuja biópsia e imunoistoquímica (IHQ) foram compatíveis com CEC de origem pulmonar. Em consulta de acompanhamento, detectou-se nódulo tireoidiano cuja punção aspirativa e IHQ de cellblock confirmaram CEC de origem pulmonar. Após quimioterapia de terceira linha, a paciente evoluiu com abdome agudo obstrutivo por massa retroperitoneal, sendo submetida a laparotomia exploradora, vindo a falecer por complicações da cirurgia. Metástases para tireoide e cólon são raramente reportadas em carcinomas epidermoides de pulmão. O envolvimento gastrointestinal por metástases de pulmão pode acometer estômago, intestino delgado e cólon, e casos de sangramento e perfuração já foram reportados. Embora ricamente vascularizada, a tireoide é sítio infrequente de metástases. Os sítios refletem prognósticos reservados na evolução clínica. Não encontramos, na literatura, relato prévio de câncer de pulmão com metástases em cólon e tireoide concomitantes em um único paciente. Abstract in english CONTEXT: Non-small cell lung cancer (NSCLC) progresses to distant metastases in most cases. The most frequent sites for distant metastases are the bones, central nervous system, adrenal glands and liver. Dissemination to the skin, myocardium, thyroid gland and intestine may occur, but is rare. CASE [...] REPORT: We describe a case of squamous cell carcinoma in the lungs, with metastases in the colon and thyroid, in a 66-year-old female patient. The lesion was unresectable and chemotherapy was started. The patient evolved with intestinal subocclusion, and colonoscopy showed the presence of a polyp. Biopsy and immunohistochemical analysis on the polyp showed that it was compatible with squamous cell carcinoma of pulmonary origin. At a follow-up consultation, the patient presented a thyroid nodule. A aspiration biopsy and cellblock immunohistochemistry confirmed the squamous cell carcinoma of pulmonary origin. After third-line chemotherapy, the patient progressed with acute obstructive abdomen due to a retroperitoneal mass. She underwent exploratory laparotomy and died due to surgical complications. Metastases to the thyroid and colon are rarely reported in cases of epidermoid carcinoma of the lungs. Gastrointestinal involvement in pulmonary metastases may affect the stomach, small intestine and colon, and cases of bleeding and perforation have already been reported. Although richly vascularized, the thyroid is an infrequent site for metastases. Such sites reflect poor prognoses for the clinical evolution. We did not find any previous reports in the literature, on lung cancer with metastases concomitantly in the colon and thyroid, in a single patient.

  1. Interest of the serous dosage of HER-2/neu, EGFr, VEGF, IL6 and Ac anti-P53 among patients damaged by an esophagus epidermoid carcinoma, type epidermoid carcinoma whom treatment was an exclusive chemoradiotherapy

    International Nuclear Information System (INIS)

    The serous concentrations of EGFr and HER2/neu seem to have a potential interest in the framework of the assumption of esophagus epidermoid carcinomas. A next step consists in comparing the serous value of these markers with their tissue expression on biopsies. A prospective study in parallel of a therapeutic trial is starting up to validate these results on a bigger number of patients. (N.C.)

  2. Prevalencia de quistes odontogénicos: Hospital Regional Valdivia entre los años 1990 y 2010 / Prevalence of odontogenic cysts: Hospital Regional Valdivia, between years 1990-2010

    Scientific Electronic Library Online (English)

    F.I., Peters; G.P., López; E.G., Preisler; C.C., Sotomayor; Z.M., Donoso; V.S., Hernández.

    2012-12-01

    Full Text Available Objetivo: Determinar la prevalencia de quistes odontogénicos en población atendida en el Hospital Regional Valdivia, en el periodo entre 1990-2010, según la última clasificación de lesiones quísticas de la Organización Mundial de la Salud (OMS), 2005. Esta investigación corresponde a un estudio desc [...] riptivo de corte transversal censal. Metodología: Se revisaron informes de biopsias del Hospital Regional Valdivia (HRV), durante un periodo de 20 años (1990-2010),seleccionando los informes con diagnósticos histopatológicos de quistes odontogénicos. Las variables a analizar fueron: año de emisión del informe, género y edad del paciente, localización anatómica de la lesión, diagnóstico histopatológico. Los datos se almacenaron en planilla de base de datos para su análisis estadístico. Resultados: De las 1.850 biopsias del territorio maxilofacial evaluadas, la prevalencia de Quistes Odontogénicos alcanzó un 11,9%. Según tipo de quiste, los más prevalente fueron el quiste radicular (84,5%), quiste dentígero (14,1%) y quiste residual (0,9%). El de menor prevalencia fue el quiste de erupción (0,5%). Un 52,7% del total de quistes odontogénicos correspondieron al género femenino. El rango de edad de presentación va entre los 4 y los 81 años (promedio 31,7±3,7 años). El área anatómica más afectada es el maxilar superior con 65,5%. Conclusión: Los Quistes odontogénicos son entidades diagnosticadas histopatológicamente en forma variable durante el periodo de tiempo comprendido entre los años 1990 y 2010, en el HRV. Se presentan en mayor frecuencia en mujeres, sin predilección por género, afectando principalmente a la 3ª década de vida. La entidad quística mas prevalente fue el quiste radicular. Abstract in english Objective: Determine the prevalence of Odontological Cysts in the attended patients of Hospital Regional Valdivia, between 1990 and 2010, according to the World Health Organization (WHO) classification of tumour like lesions, 2005. This investigation corresponds to a descriptive cross-sectional stud [...] y. Method: The biopsy reports of the Hospital Regional Valdivia, during a 20 years period (1990-2010), were analyzed, selecting those with Odontological Cysts histopathological diagnosis. The analyzed variables were: year of the biopsy report; patient's gender and age; anatomical location of the lesion and histopathological diagnosis. The extracted data were stored in a data base for descriptive statistical analysis. Results: Within the 1850 biopsies found from the maxilofacial region, the Odontological Cysts prevalence was 11.9%. According to the type of cyst, the most prevalent was Radicular/Periapical Cyst (84.5%), followed by Dentigerous/Folicular Cyst (14.1%), and then Residual Cyst (0.9%). The least prevalent was Eruption Cyst (0.5%). 52.7% of all Odontological Cystswere found in women. The cysts's presentation among age ranges was between 4 and 81 years old (average 31.7±3.7 years old). The most frequently affected anatomical region was the superior maxilla (65.5%). Conclusion: Odontological Cysts are histopathologically diagnosed lesions in varying ways between 1990 and 2010 at Hospital Regional Valdivia. Without gender predilection, they present most commonly affecting women, mainly those in the 3rd decade of life. The most common cystic lesion found was Radicular/Periapical Cyst.

  3. Investigación experimental de la equinococosis canina a partir de quiste hidatídico de origen porcino en México

    Directory of Open Access Journals (Sweden)

    Zuñiga-A Ismael

    1999-01-01

    Full Text Available OBJETIVO: Para evaluar la infección y obtener el estado adulto del cestodos, se buscó reproducir la equinococosis en perros a partir de quiste hidatídico de origen porcino. MÉTODOS: Se formaron 2 grupos, uno de 5 y otro de 3 perros, a cada animal del grupo experimental se le dió 2 g de membrana germinativa de quíste hidatídico fértil por vía oral, el segundo grupo fue testigo. Ambos grupos fueron evaluados clínica, serológica y parasitológicamente, en el grupo experimental se sacrificó un animal el día 35 de la infección y los siguientes cada 5 dias hasta el 55, en el segundo grupo todos se sacrificaron el día 55. Se observaron huevos del cestodos en heces a partir del dia 51 postinfección. La evaluación morfológica se realizó mediante observación microscópica del raspado de mucosa intestinal. RESULTADOS: De 50 cestodos analizados, 10 de cada uno de los perros infectados, 49 (98% presentaron 3 proglótidos y 1 (2% tenía 4; 18 (36% de los cestodos presentaban un proglótido grávido. La longitud de los estróbilos varió de 1,6 a 2,6 mm. El número promedio de los ganchos largos y cortos fue de 31 y 34 respectivamente. La longitud de los ganchos largos varió entre 0,081 y 0,09 mm, los ganchos cortos fluctuaron entre 0,034 y 0,041 mm. En los perros evaluados clínicamente, el número de leucocitos y la cantidad de proteínas plasmáticas fue significativamente mayor en el grupo testigo (P < 0,05; la cantidad de alfa globulinas fue mayor en el grupo infectado (P < 0,05. CONCLUSIONES: Los resultados permiten confirmar el ciclo perro-cerdo y una infección subclínica en los huéspedes definitivos, lo que dificulta su diagnóstico y control en una especie intimamente relacionada con el hombre.

  4. Investigación experimental de la equinococosis canina a partir de quiste hidatídico de origen porcino en México

    Directory of Open Access Journals (Sweden)

    Ismael Zuñiga-A

    1999-06-01

    Full Text Available OBJETIVO: Para evaluar la infección y obtener el estado adulto del cestodos, se buscó reproducir la equinococosis en perros a partir de quiste hidatídico de origen porcino. MÉTODOS: Se formaron 2 grupos, uno de 5 y otro de 3 perros, a cada animal del grupo experimental se le dió 2 g de membrana germinativa de quíste hidatídico fértil por vía oral, el segundo grupo fue testigo. Ambos grupos fueron evaluados clínica, serológica y parasitológicamente, en el grupo experimental se sacrificó un animal el día 35 de la infección y los siguientes cada 5 dias hasta el 55, en el segundo grupo todos se sacrificaron el día 55. Se observaron huevos del cestodos en heces a partir del dia 51 postinfección. La evaluación morfológica se realizó mediante observación microscópica del raspado de mucosa intestinal. RESULTADOS: De 50 cestodos analizados, 10 de cada uno de los perros infectados, 49 (98% presentaron 3 proglótidos y 1 (2% tenía 4; 18 (36% de los cestodos presentaban un proglótido grávido. La longitud de los estróbilos varió de 1,6 a 2,6 mm. El número promedio de los ganchos largos y cortos fue de 31 y 34 respectivamente. La longitud de los ganchos largos varió entre 0,081 y 0,09 mm, los ganchos cortos fluctuaron entre 0,034 y 0,041 mm. En los perros evaluados clínicamente, el número de leucocitos y la cantidad de proteínas plasmáticas fue significativamente mayor en el grupo testigo (P < 0,05; la cantidad de alfa globulinas fue mayor en el grupo infectado (P < 0,05. CONCLUSIONES: Los resultados permiten confirmar el ciclo perro-cerdo y una infección subclínica en los huéspedes definitivos, lo que dificulta su diagnóstico y control en una especie intimamente relacionada con el hombre.

  5. Anodoncia parcial relacionada con Quiste Dentígero y Quiste Traumático. revisión de la literatura y presentación de un caso / PARTIAL ANODONTIA RELATED TO DENTIGEROUS CYST AND TRAUMATIC CYST. REVIEW OF THE LITERATURE AND PRESENTATION OF A CASE.

    Scientific Electronic Library Online (English)

    Yuli, Moret; José María, González.

    2003-08-01

    Full Text Available Resumen La Anodoncia parcial es una anomalía de número caracterizada por la ausencia congénita de dientes primarios y permanentes. Se ha designado con otros términos como agenesia dental, oligodoncia e Hipodoncia. Se presenta un caso de una niña afectada por esta enfermedad teniendo en cuenta que es [...] un caso aislado sin otros rasgos de patología genética sindromática y que a la vez estaba relacionado con dos patologías: quiste Traumático y quiste Dentígero. Se planificó tratamiento combinado: quirúrgico y toma de muestra para estudio histopatológico, ortodoncia, prótesis. Evaluaciones periódicas. Abstract in english Abstract Partial anodontia is an abnormality of number characterized by the congenital absence of primary and permanent teeth. It has been designated by other names such as dental agenesia, oligodoncy, and hypodoncy. We present the case of a male child with this disease, bearing in mind that this is [...] an isolate case with no other elements of syndromatic genetic pathology, and that it was also related to two other pathologies: Traumatic Cyst and Dentigerous Cyst. A combined treatment involving surgery and sampling for histopathological study, orthodoncy, and prosthesis was planned, calling for periodic evaluations.

  6. Efficacy of Liposomal Monensin on the Enhancement of the Antitumour Activity of Liposomal Ricin in Human Epidermoid Carcinoma (KB) Cells

    OpenAIRE

    Tyagi, N; S. S. Rathore; Ghosh, P C

    2013-01-01

    The monensin, known to enhance the cytotoxicity of ricin and ricin-based immunotoxins is a very hydrophobic molecule and this limits its administration in optimum doses under in vivo conditions. In order to realise its full potential, monensin was intercalated into various liposomal formulations and its ability to potentiate the cytotoxicity of ricin liposomes in human epidermoid carcinoma (KB) cells was studied. It was observed that ricin cytotoxicity enhancing ability of monensin liposome d...

  7. A simple vitrification method for cryobanking avian testicular tissue

    Science.gov (United States)

    Cryopreservation of testicular tissue is a promising method of preserving male reproductive potential for avian species. This study was conducted to assess whether a vitrification method can be used to preserve avian testicular tissue, using the Japanese quail (Coturnix japonica) as a model. A sim...

  8. [Isolated testicular tuberculosis in children. Report of 2 Malagasy cases].

    Science.gov (United States)

    Rakototiana, A F; Hunald, F A; Razafimanjato, N; Ralahy, M F; Rakoto-Ratsimba, H N; Rantomalala, H Y H

    2009-02-01

    Isolated testicular tuberculosis is rare. The authors report 2 cases in children. The clinical features had no specificity: one case of hydrocele and 1 case of acute scrotum inflammation. Surgical exploration showed testicular nodules in both cases. Only histological examination provided the definitive diagnosis. The details of diagnosis and treatment are discussed and compared to the information available in the literature. PMID:19070998

  9. Testicular descent: INSL3, testosterone, genes and the intrauterine milieu

    DEFF Research Database (Denmark)

    Bay, Katrine; Main, Katharina M; Toppari, Jorma; Skakkebæk, Niels E

    2011-01-01

    Complete testicular descent is a sign of, and a prerequisite for, normal testicular function in adult life. The process of testis descent is dependent on gubernacular growth and reorganization, which is regulated by the Leydig cell hormones insulin-like peptide 3 (INSL3) and testosterone. Investi...

  10. Testicular cancer knowledge among deaf and hearing men.

    Science.gov (United States)

    Sacks, Loren; Nakaji, Melanie; Harry, Kadie M; Oen, Marcia; Malcarne, Vanessa L; Sadler, Georgia Robins

    2013-09-01

    Testicular cancer typically affects young and middle-aged men. An educational video about prostate and testicular cancer was created in American Sign Language, with English open captioning and voice overlay, so that it could be viewed by audiences of diverse ages and hearing characteristics. This study recruited young Deaf (n = 85) and hearing (n = 90) adult males to help evaluate the educational value of the testicular cancer portion of this video. Participants completed surveys about their general, testicular, and total cancer knowledge before and after viewing the video. Although hearing men had higher pre-test scores than Deaf men, both Deaf and hearing men demonstrated significant increases in General, Testicular, and Total Cancer Knowledge scores after viewing the intervention video. Overall, results demonstrate the value of the video to Deaf and hearing men. PMID:23813488

  11. Leucoencefalopatía megalencefálica con quistes subcorticales (enfermedad de Van der Knaap) / Megalencephalic leukoencephalopathy with subcortical cysts (Van der Knapp disease)

    Scientific Electronic Library Online (English)

    Hugo Hernán, Abarca Barriga; María del Carmen, Castro Mujica; Bertha Elena, Gallardo Jugo.

    2013-03-01

    Full Text Available La leucoencefalopatía megalencefálica con quistes subcorticales es un desorden genético autosómico recesivo, debido a mutaciones en los genes megalencephalic leukoencephalopathy with subcortical cyst 1 (MLC1) o hepatocyte cell adhesion molecule (HEPACAM). Esta enfermedad de la sustancia blanca se ca [...] racteriza por macrocefalia de inicio temprano, deterioro motor y mental progresivo, ataxia y crisis epilépticas. La resonancia magnética nuclear muestra edema, compromiso difuso de la sustancia blanca y quistes subcorticales frontotemporales. Se presenta el primer caso reportado en Perú, de una niña con hallazgos clínicos y de la resonancia magnética nuclear típicos, con mutaciones heterocigotas en el gen MLC1. Abstract in english Megalencephalic leukoencephalopathy with subcortical cysts is a recessive autosomal genetic disorder, due to mutations in the gen megaloencephalic leukoencephalopathy with subcortical cyst 1 (MLC1) or hepatocyst cell adhesion molecule (HEPACAM). This white matter disease is characterized by macroenc [...] ephaly of early onset, progressive motor or mental deterioration, ataxia and epileptic crises. Magnetic resonance imaging shows edema, diffuse compromise of the white matter and frontotemporal subcortical cysts. Here is the first case reported in Peru; it is a girl with clinical findings and typical findings disclosed in the nuclear magnetic resonance imaging in addition to heterocygotic mutations in the gen MLC1.

  12. Quiste gigante de ovario en una adolescente: presentación de un caso Giant ovarian cyst in an adolescent: a case report

    Directory of Open Access Journals (Sweden)

    Olimpia Contreras Leal

    2009-06-01

    Full Text Available Se trata de una adolescente de 13 años de edad con antecedentes de salud con menarquía a los 11 años y metrorragias frecuentes que acudió a consulta de Pediatría del Hospital Regional de Bata Litoral en la República de Guinea Ecuatorial por aumento de volumen del abdomen, específicamente del hemiabdomen derecho, es ínter consultada con Ginecología por sospecha de tumor de ovario, lo cual se corroboró por ultrasonografía. Se realiza intervención quirúrgica encontrándose quiste gigante de ovario derecho que pesó 6 kg del cual no tuvimos el diagnóstico histológico por no disponer de laboratorio de Anatomía Patológica, pero por las características macroscópicas se trató como un Quiste Seroso Simple, La paciente tuvo una evolución favorable.A 13- year-old girl is presented, having undergone a good health and menarche at 11 years old, she has had vaginal bleeding frequently, and came to Pediatrics Clinics at Bata Littoral Provincial Hospital in Equatorial Guinea with the Pediatrician. The main symptoms were abdominal volume increase, more specifically at right hemiabdomen and pain to deep palpation. This case was sent to the Gynecologist and an ovarian tumor was suspected, afterwards verified by the ultrasonographic study. The patients was referred to surgery, the final clinical diagnosis was Right Ovary Giant Cyst, weighing 6 kg. The histological diagnosis was not assessed because the lack of pathology lab in this country. Following the macroscopic features the tumor was treated as a Simple Serous Cyst. The patient had a favorable evolution.

  13. Quiste congénito de la valécula con alteraciones del peso: Caso clínico / Congenital vallecular cyst with weight disorders: Case report

    Scientific Electronic Library Online (English)

    Jhonder Xavier, Salazar Guilarte; José Mauri, Barbera.

    2013-04-01

    Full Text Available Los quistes de la valécula son un trastorno raro en los niños; el estridor es el síntoma más frecuente y la alteración del crecimiento, el más infrecuente. Se presenta el caso de un niño de 2 meses referido por la escasa ganancia ponderal desde su nacimiento, con antecedentes de atragantamiento al a [...] limentarse. No presentaba dificultad respiratoria, pero llamaba la atención la respiración bucal y la hiperextensión del cuello con lateralización hacia la derecha. El esofagograma mostró una masa hipofaríngea que desplazaba la laringe y reflujo del medio de contraste hacia el árbol bronquial. Por laringoscopia directa se resecó un quiste con técnica de marsupialización. La evolución fue favorable, sin recidivas, hasta el cuarto mes de seguimiento. Abstract in english Vallecula cysts are a rare condition in children, with stridor being the most common symptom and growth alterations the more uncommon. We present a 2 months-old child referred by low weight gain from birth, with a history of choking when feeding. He had no respiratory distress but struck mouth breat [...] hing and neck hyperextension with lateralization to the right. The esophagogram showed a mass displacing hypopharynx and larynx reflux of contrast into the bronchial tree. The cyst was resected by direct laryngoscopy with marsupialization technique. The outcome was favorable, without recurrence until the fourth month of monitoring.

  14. Reacción anafiláctica secundaria a quiste hidatídico hepático roto / Anaphylactic reaction secondary to a ruptured liver hydatid cyst. Case report

    Scientific Electronic Library Online (English)

    Juan L, Morales G; Claudio, Tapia C; César, Muñoz C; Eduardo, Otero V; Ricardo, Rebolledo R.

    2011-06-01

    Full Text Available La hidatidosis es una enfermedad parasitaria, zoonótica y endémica de gran importancia en nuestro país. El quiste hidatídico no complicado suele ser asintomático y es más frecuente encontrarlo en población adulta, siendo infrecuente su diagnóstico en la población pediátrica. Presentamos el caso de u [...] na paciente de 4 años de edad derivada al Servicio de Urgencia del Hospital de Chillán por cuadro de abdomen agudo posterior a trauma abdominal con manubrio de bicicleta, cuyo estudio tomográfico reveló la presencia de quiste hidatídico hepático y pulmonar rotos, que evoluciona con reacción anafiláctica secundaria. Abstract in english We report a four years old girl consulting in the emergency room for severe abdominal pain and vomiting secondary to a blunt abdominal trauma during a bicycling accident. A chest and abdomen CAT scan showed ruptured hydatid cysts in the lung and liver and free intraperitoneal fluid. During evolution [...] , the patient developed respiratory distress, bronchial obstruction, a papular exanthema and edema. Due to lack of response to steroids, she was operated excising the ruptured hepatic cyst and performing a peritoneal lavage. The patient had a good postoperative evolution. In a second surgical procedure, the lung cyst was excised. The patient is currently receiving albendazole and is asymptomatic after nine months of follow up.

  15. Quiste hidatídico retro-peritoneal: Una enfermedad frecuente en una ubicación inusual Retroperitoneal hydatid cyst: A common disease in a rare location

    Directory of Open Access Journals (Sweden)

    Stephanie Subercaseaux V

    2010-12-01

    Full Text Available La hidatidosis sigue siendo un problema prevalente en áreas endémicas. Presentamos el caso de un quiste hidatídico primario ubicado en el espacio retro-peritoneal. Mujer de 54 años, procedente de área rural del sur de Chile, hospitalizada por cuadro de coxalgia derecha y aumento de volumen glúteo, con tres meses de evolución. Se realizó el diagnóstico de hidatidosis complicada por medio de exámenes de imágenes, tests serológicos y anatomía patológica. No se demostraron quistes hidatídicos en otras ubicaciones. Se realizó un drenaje percutáneo del quiste infectado y se administraron antihelmínticos durante 12 semanas y actualmente permanece en seguimiento cercano con buena respuesta al tratamiento. El quiste hidatídico debe ser considerado en el diagnóstico diferencial de masas quísticas retro-peritoneales, especialmente en áreas endémicas.Echinococcal disease remains a major problem within some endemic areas. We report a case of a single primary echinococcal cyst located in the retroperitoneal space. A 54-year-old woman, born in a rural area of southern Chile, was admitted with a 3-month history of right hip pain and painful swelling of the gluteal region. Hidatid disease was confirmed with serologic test, radiological examinations and histo-pathology. There were no cysts in any other location. A percutaneous drainage was performed and antihelminthics were administered for 12 weeks and is now being closely followed up, with good response to therapy. Especially in the endemic areas hydatid cyst should be considered when evaluating retroperitoneal cystic masses.

  16. Radiotherapy Treatment Planning for Testicular Seminoma

    International Nuclear Information System (INIS)

    Virtually all patients with Stage I testicular seminoma are cured regardless of postorchiectomy management. For patients treated with adjuvant radiotherapy, late toxicity is a major concern. However, toxicity may be limited by radiotherapy techniques that minimize radiation exposure of healthy normal tissues. This article is an evidence-based review that provides radiotherapy treatment planning recommendations for testicular seminoma. The minority of Stage I patients who choose adjuvant treatment over surveillance may be considered for (1) para-aortic irradiation to 20 Gy in 10 fractions, or (2) carboplatin chemotherapy consisting of area under the curve, AUC = 7 × 1?2 cycles. Two-dimensional radiotherapy based on bony anatomy is a simple and effective treatment for Stage IIA or IIB testicular seminoma. Centers with expertise in vascular and nodal anatomy may consider use of anteroposterior–posteroanterior fields based on three-dimensional conformal radiotherapy instead. For modified dog-leg fields delivering 20 Gy in 10 fractions, clinical studies support placement of the inferior border at the top of the acetabulum. Clinical and nodal mapping studies support placement of the superior border of all radiotherapy fields at the top of the T12 vertebral body. For Stage IIA and IIB patients, an anteroposterior–posteroanterior boost is then delivered to the adenopathy with a 2-cm margin to the block edge. The boost dose consists of 10 Gy in 5 fractions for Stage IIA and 16 Gy in 8 fractions for Stage IIB. Alternatively, bleomycin, etoposide, and cisplatin chemotherapy for 3 cycles or etoposide and cisplatin chemotherapy for 4 cycles may be delivered to Stage IIA or IIB patients (e.g., if they have a horseshoe kidney, inflammatory bowel disease, or a history of radiotherapy).

  17. Radiotherapy Treatment Planning for Testicular Seminoma

    Energy Technology Data Exchange (ETDEWEB)

    Wilder, Richard B., E-mail: richardbwilder@yahoo.com [Department of Radiation Oncology, Moffitt Cancer Center, Tampa, FL (United States); Buyyounouski, Mark K. [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States); Efstathiou, Jason A. [Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA (United States); Beard, Clair J. [Department of Radiation Oncology, Dana-Farber/Brigham and Women' s Cancer Center, Boston, MA (United States)

    2012-07-15

    Virtually all patients with Stage I testicular seminoma are cured regardless of postorchiectomy management. For patients treated with adjuvant radiotherapy, late toxicity is a major concern. However, toxicity may be limited by radiotherapy techniques that minimize radiation exposure of healthy normal tissues. This article is an evidence-based review that provides radiotherapy treatment planning recommendations for testicular seminoma. The minority of Stage I patients who choose adjuvant treatment over surveillance may be considered for (1) para-aortic irradiation to 20 Gy in 10 fractions, or (2) carboplatin chemotherapy consisting of area under the curve, AUC = 7 Multiplication-Sign 1-2 cycles. Two-dimensional radiotherapy based on bony anatomy is a simple and effective treatment for Stage IIA or IIB testicular seminoma. Centers with expertise in vascular and nodal anatomy may consider use of anteroposterior-posteroanterior fields based on three-dimensional conformal radiotherapy instead. For modified dog-leg fields delivering 20 Gy in 10 fractions, clinical studies support placement of the inferior border at the top of the acetabulum. Clinical and nodal mapping studies support placement of the superior border of all radiotherapy fields at the top of the T12 vertebral body. For Stage IIA and IIB patients, an anteroposterior-posteroanterior boost is then delivered to the adenopathy with a 2-cm margin to the block edge. The boost dose consists of 10 Gy in 5 fractions for Stage IIA and 16 Gy in 8 fractions for Stage IIB. Alternatively, bleomycin, etoposide, and cisplatin chemotherapy for 3 cycles or etoposide and cisplatin chemotherapy for 4 cycles may be delivered to Stage IIA or IIB patients (e.g., if they have a horseshoe kidney, inflammatory bowel disease, or a history of radiotherapy).

  18. TESTICULAR CANCER – THE SUCCESS OF MULTIMODAL THERAPY

    Directory of Open Access Journals (Sweden)

    L. Miron

    2006-01-01

    Full Text Available Testicular neoplasia constitutes a chapter of particular interest in oncology, given its increased curability in comparison with most solid tumors. Early diagnosis is important because it allows the patients to be treated in the first stages of the disease, in which morbidity associated with therapy is minimal, and increased survival represents certitude. The medical staff, as well as the general population, must be advised upon suggestive signs and symptoms, and also on the imaging characteristics of such cancers (ultrasound and CAT scans being in the spotlight, so that the period of time until confirmation of the diagnosis (by pathology exam – which in turn influences therapy decision – is obtained may be as short as possible. Surgery represents a very important component of multimodal therapeutic strategy for patients diagnosed with testicular cancer, both for low/volume tumors and for the more advanced stages of disease. Surgical interventions (orchiectomy, retroperitoneal lymph node resection with or without sympathic nerve preservation, resection of singular metastases contribute decisively to the high percentage of long term cures, and can play a role in increasing the survival of patients with chemoresistant metastatic disease. Chemotherapy is mandatory in the treatment of locally advanced and metastasis seminomatous germ cell tumors (GCT. This may be seen also as an option to annihilate possible pathology diagnostic errors (mostly due to lack of tumour marker dosing which determine a non-seminomatous GCT to be treated as a seminoma, thus greatly diminishing therapeutic efficacy. There are several chemotherapeutic agents with extremely efficient activity on seminomatous testicular tumours, but the etoposide/cisplatin protocol remains still the gold standard. Non-seminomatous GCTs have a lesser response to chemotherapy and therefore a higher relapse rate and a poorer prognosis.

  19. [Sigmovaginoplasty in patient with testicular feminization syndrome].

    Science.gov (United States)

    Komiakov, B K; Guliev, B G; Onoshko, M V

    2014-01-01

    The article presents the description of the clinical observation of the 36 years old patient with testicular feminization syndrome: genetic (karyotype 46 XY) and gonadal male sex, female external genitalia and the absence of derivatives of Mullerian ducts (uterus, fallopian tubes, the upper third of the vagina). At the first stage, testes were removed; then, vaginoplasty using segment of the sigmoid colon for possible sexual intercourse was performed. There were no complications. Currently, the patient's condition is satisfactory; she lives a regular sex life. PMID:25211931

  20. Quality of Life of Testicular Cancer Survivors

    OpenAIRE

    Fleer, Joke,

    2006-01-01

    Men who are diagnosed with testicular cancer are generally young. As a consequence of the treatment they receive nowadays, they are likely to cure from the disease, even when they have metastases. This means that they have to live with possible short- and long-term sequel of diagnosis and treatment for many years. Survivors who do not have the resources necessary to cope with such physical and psychosocial sequel, may find it more difficult to adjust to their altered life situation and experi...

  1. Definitive radiation therapy for clinical stage N0-N1 epidermoid carcinoma of the lung

    International Nuclear Information System (INIS)

    From 1976 through 1989, 94 patients with epidermoid carcinoma of the lung without mediastinal nodal involvement were treated with definitive radiation therapy (RT) at Gunma University Hospital. All patients were treated with 10 MV X-rays and the mediastinum was treated in 86% of the patients. The total dose ranged from 60 Gy to 80 Gy with once-daily conventional fractionation. The actuarial two and five-year survival rates of the entire group were 44% and 22%, respectively, with a median survival time (MST) of 17 months. Patients with a performance status of 0-1 lived longer than those with a status of 2 or more (MST 22.5 vs. 12 months). The survival of 60 patients with T2 tumors was better than that of 24 patients with T3 tumors (MST 19 vs. 13.5 months). Forty-seven patients with tumors less than 5 cm in diameter had a two-year progression rate of 25%, in comparison with 39% for 47 patients with tumors greater than 5 cm. The survival difference between these two groups was statistically significant (p<0.01). Patients given a total dose of 80 Gy or over had only 20% local progression at the time of the last follow-up, but they had a lower long-term survival rate than those given a total dose of 60-74 Gy because of the development of pulmonary insufficiency after high-dose irradiation. There was no relapse in the field given 40 Gy or more to the mediastinum for prophylaxis in the patients with no evidence of primary progression. The actuarial five-year survival rates for the patients given 40 Gy or more to the mediastinum, and for the patients given less than 40 Gy were 32% and 9%, respectively. These was a statistically significant difference between these two survival curves, (p<0.05). Differences in survival did not depend on age, sex, or location of the primary tumor. These results should provide support for definitive RT to manage patients with medically inoperable or unresectable epidermoid carcinoma of the lung without mediastinal nodal involvement. (author)

  2. Radiation therapy for epidermoid carcinoma of the anal canal, clinical and treatment factors associated with outcome

    International Nuclear Information System (INIS)

    Background and purpose: In recent years, treatment with combined chemotherapy and radiation has become the standard of care for epidermoid carcinoma of the anus. However, optimal radiotherapy techniques and doses are not well established. Materials and methods: During the period 1975-1997, 106 patients with epidermoid carcinoma of the anal canal underwent radiation therapy. Treatment policies evolved from radiation therapy alone or with surgery, to combined chemotherapy and radiation followed by surgery, to combined chemotherapy and radiation. Results: Overall 74% of patients were NED (no evidence of disease) at last follow-up. The most important clinical correlate with ultimate freedom from disease (includes the contribution of salvage surgery) was extent of disease. The 5-year ultimate freedom from disease was 87±5% for T1/T2N0, 78±10% for T3N0 (15% salvaged by surgery), and 43±10% for either T4N0 or any N+ lesions (P<0.001, Tarone-Ware). There was no difference between planned vs. expectant surgery (5-year ultimate NED: 67±11% planned surgery vs. 73±5% expectant surgery). The most important correlate with late toxicity was a history of major pelvic surgery (surgical vs. non-surgical group: P=0.013, Fisher's exact test, two-tailed summation). Thirty-three additional malignancies have been seen in 26 patients. The most common additional malignancies were gynecologic (nine cases), head and neck (six cases), and lung cancer (five cases). Conclusions: For T1/T2N0 disease, moderate doses of radiation combined with chemotherapy provided adequate treatment. T4N0 and N+ lesions are the most appropriate candidates for investigational protocols evaluating dose intensification. T3N0 tumors may also be appropriate for investigation; however, dose intensification may ultimately prove counterproductive if the cure rate is not improved and salvage surgery is rendered more difficult. The volume of irradiated small bowel should be minimized for patients who have a past history of major pelvic surgery or who (because of locally advanced tumors) may need salvage surgery in the future. Because of the occurrence of additional malignancy, patients with anal cancer should receive general oncologic screening in long-term follow-up

  3. Quiste aracnoideo espinal epidural postraumático: presentación de un caso / Postraumatic epidural arachnoid spinal cyst: case report

    Scientific Electronic Library Online (English)

    O., Hernández-León; F.R., Pérez-Nogueira; N., Corrales.

    2011-06-01

    Full Text Available Introducción. Los quistes aracnoideos extradurales espinales son lesiones poco frecuentes. Clínicamente se caracterizan por un cuadro mielopático progresivo, asociado o no a crisis radiculares. Para su diagnóstico radiológico las técnicas de resonancia magnética actuales posibilitan definirlos adecu [...] adamente y conocer su localización topográfica. Los antecedentes patológicos del paciente son esenciales para establecer se etiología encontrándose en muchos casos una historia de trauma espinal, cirugía y menos frecuentemente anomalías congénitas asociadas. El tratamiento en la mayoría de los casos es quirúrgico. Caso clínico. Presentamos el caso de un paciente de 35 años con antecedentes de una hemisección medular dorsal por arma blanca hace dos años. Evolutivamente se deterioran sus funciones motoras presentándose con una paraparesia espástica. Los estudios radiológicos mostraron la presencia de la lesión quística extradural comprimiendo el cordón medular a nivel dorsal (D3-D4). Se realizó cirugía descompresiva y se identificó un desgarro meníngeo a ese nivel que fue suturado. La evolución postoperatoria fue satisfactoria. Conclusiones. El tratamiento quirúrgico efectivo de estas lesiones está dado por la detección del defecto meníngeo y su cierre. Abstract in english Introduction. Extradural arachnoid spinal cysts are unfrequent lesions that are associated with spinal trauma, surgery and less frequently with congenital anomalies. The clinical manifestations are similar to those seen with other compressive spinal cord lesions. Magnetic resonance techniques allow [...] to diagnose correctly this pathology and to define its thopographic situation. The pathologic history of the patient is essencial to establish the ethiology. Surgery is the elective treatment in most cases. Clinical case. The patient is a 35 years old man who has a medical history of penetrating spinal trauma two years ago. In that instance he suffered an unilateral spinal cord section at D2-D3 level with the corresponding Brown Sequard syndrome. A small wound was detected at the skin dorsal level and it was closed without difficulties. At the beginning, he improved his motor right leg function with rehabilitation and vitamins. After two years of good recovery he came to our hospital suffering a neurological deterioration of six months of evolution. The physical examination revealed an spastic paraparesis. Magnetic resonance was performed demonstrating a cystic extradural collection compressing the spinal cord at D3-D4 level. Surgical decompressive treatment allowed to excise the cyst and it was possible to define a dural tear that was closed successfully. The outcome was good with restoration of the initial motor function that he had after the spinal trauma. Conclusions. Surgical management of postraumatic epidural arachnoid spinal cyst allows to detect the meningeal tear and to close it, which is highly effective on these kinds of lesions.

  4. Non-seminomatous testicular germ cell tumours

    International Nuclear Information System (INIS)

    This report deals with the preliminary results of trials in the DATECA project with stage I, II and III patients with non-seminomatous germ cell tumours. Stage 1 patients were randomized between infradiaphragmatic irradiation and observation. No significant difference in recurrence rates has been observed as yet. Eighteen of 95 patients had recurrence with a median time to relapse of 3 months. Fifteen patients achieved complete remission after treatment by combiantion chemotherapy while 3 patients are still undergoing treatment. Stage II patients received 6 series of cis-platinum, bleomycin, and vinblastine. The patients were initially randomized to receive chemotherapy alone versus chemotherapy plus irradiation. Irradiation led to increased toxicity and decreased doses of the antineoplastic drugs. Fifty-one patients were studied. The overall complete remission rate was 89 per cent including 7 patients who achieved complete remission after secondary surgery. Three patients died from testicular tumours and two toxic deaths occurred in this group. Stage III patients were treated with 6 series of cis-platinum, bleomycin, and vinblastine. Fifty patients were studied. The complete remission rate was 72 per cent including 2 patients who achieved complete remission after secondary surgery. Sixteen patients relapsed after achieving complete remission with a median time to relapse of 4 months. Eight of these died, 4 achieved a new complete remission, while 4 patients are still under treatment. Sixty per cent of the patients are at present alive without evidence of disease, while 12 patients died from testicular tumours and 2 from toxic side effects. (orig.)

  5. Combination of radiotherapy and cetuximab for patients suffering from of an advanced and non operable epidermoid carcinoma of the ORL sphere: results and side effects; Association de radiotherapie et de cetuximab chez des patients atteints d'un carcinome epidermoide de la sphere ORL evolue non operable: resultats et effets secondaires

    Energy Technology Data Exchange (ETDEWEB)

    Acevedo, C.; Valette, G.; Bouchekoua, M.; Marianowski, R.; Pradier, O. [CHU Morvan, 29 - Brest (France)

    2010-10-15

    The authors report a retrospective survey of a set of locally advanced epidermoid carcinomas treated by irradiation and cetuximab. They assessed the response to the treatment, the specific survival, and the global survival as well as the tolerance. The survey is based on 31 men and 5 women suffering from different stage 4 non-metastatic advanced epidermoid carcinomas of the ORL sphere. Short communication

  6. Incidence of testicular microlithiasis in patients with ?-thalassemia major.

    Science.gov (United States)

    Rahimi, Rahil; Foroughi, Amin Abolhasani; Haghpanah, Sezaneh; Bahmanyar, Maryam; Jelodari, Shohreh; De Sanctis, Vincenzo; Karimi, Mehran

    2015-11-01

    We assessed the prevalence of testicular microlithiasis by scrotal ultrasonography in ?-thalassemia major patients older than 10 years and evaluated the association with serum ferritin levels, calcium (Ca), phosphate (Ph), and parathyroid hormone levels (PTH). In this cross-sectional study, 132 male ?-thalassemia major patients from 300 male patients older than 10 years old were randomly evaluated by scrotal ultrasonography. Parathyroid hormone, calcium, phosphate, and serum ferritin levels were also evaluated. All of the patients were urologically asymptomatic. One hundred healthy age-matched subjects were selected as control group. Testicular microlithiasis was found in 16 patients and 1 individual in control group (12.1 vs 1 %; p?=?0.003). Testicular microlithiasis was associated with age and high serum ferritin levels, but there was no association between Ca, Ph, and PTH levels; blood transfusion; and oral or subcutaneous iron chelation therapy. Also, there was no significant correlation between hyperparathyroidism, history of viral hepatitis, and splenectomy with testicular microlithiasis. The frequency of testicular microlithiasis in ?-thalassemia major patients was higher than previously reported. A correlation was found between testicular microlithiasis with age and serum ferritin levels, so regular and adequate iron chelator therapy (at least 10-12 h per day for 5-6 days a week) is recommended. We suggest a close observation and treatment with iron-chelating agents of these patients. Since testicular microlithiasis is occasionally associated with germ cell tumors, clinical and sonographic follow-up is recommended. PMID:26251156

  7. Evaluation of Doppler Indices in Varicocele-Related Testicular Atrophy

    Directory of Open Access Journals (Sweden)

    Masoud Nemati

    2010-05-01

    Full Text Available Background/Objective: Varicocele is a well-recognized cause of decreased testicular function and atrophy and occurs in approximately 15-20% of all men and 40% of infertile men. The aim of this study was to evaluate varicocele-related testicular atrophy with Duplex sonography. "nPatients and Methods: Fifty patients (mean age 24±7.43 with testicular atrophy due to varicocele were included in the study during 2005-2008."nResults: Echogenicity of the atrophic testis was homogeneous. The mean peak systolic velocity (PSV and resistive index (RI in intratesticular arteries for atrophic and normal testes were 5.45 ± 2.22 cm/s, 0.63±0.12 and 6.38 ±2.12 cm/s, 0.61± 0.17, respectively. The differences were not significant (P > 0.05. "nConclusion: Varicocele-related testicular atrophy is not associated with testicular parenchymal heterogeneity and it does not affect the intratesticular and testicular arterial PSV or RI."nKeywords: Varicocele, Testicular Atrophy, Peak Systolic Velocity, Resistive Index

  8. Detecção do Rearranjo da Proteína BCL2/JH em Carcinomas Epidermoides de Boca e Faringe

    Directory of Open Access Journals (Sweden)

    Montovani, Jair

    2010-09-01

    Full Text Available Introdução: A proteína BCL2 encontrada na membrana mitocondrial interna, regula a apoptose inibindo a morte celular programada. A translocação (14;18, detectada em 70 a 85% dos linfomas foliculares, leva a superexpressão da proteína BCL2, pela justaposição do gene BCL2 ao segmento JH do gene da cadeia pesada da imunoglobulina. Porém, os achados da expressão da BCL2 em carcinoma de cabeça e pescoço são contraditórios. Objetivo: Investigar a presença da translocação (14;18 do gene BCL2 em carcinomas de cabeça e pescoço. Método: Foram examinadas 16 amostras de DNA, sendo 13 de carcinomas de células escamosas (CCE e 3 de epidermoide (CE, por meio da reação em cadeia da polimerase (PCR. Resultados: O rearranjo BCL2/JH foi encontrado em 2 (15% dos 13 casos de CCE e em nenhum dos 3 casos de CE. A média de frequência de moléculas com rearranjo foi de 46,44 x 107. Não foi observada associação entre a presença de rearranjo e a exposição ao tabaco e álcool (p=0,6545. Conclusão: Diferente dos resultados encontrados em linfomas foliculares a presença da translocação (14;18 em carcinomas de cabeça e pescoço não é comum e, quando ocorre, pode ser uma mutação ocasional não associada a exposição ao tabaco e álcool.

  9. Preoperative chemotherapy and radiotherapy in the managment of epidermoid carcinoma of the anal canal

    International Nuclear Information System (INIS)

    Sixteen patients affected by epidermoid carcinoma of the anal canal were treated preoperatively by means of an i.v. infusion of mitomycin C (15 mg/m2) on day 1 and 5-fluorouracil (750 mg/m2) days 1 to 5, followed by radiotherapy (3000 R in 3 weeks). Four to 6 weeks after the end of radiotherapy the response to the preoperative treatment was evaluated by means of biopsy. A reduction of the neoplastic mass was observed in 13 of the 16 patients. An evident correlation exists between the stage of the tumor and 1) the response to preoperative treatment 2) local recurrence, and 3) long-term survival. In fact: 3/4 T1 patients reached a complete response (CR), and 1/4 T1, 5/5 T2 and 4/7 T3 patients achieved a partial response (PR); only 3/7 T3 patients never responded to preoperative treatment. After the initial surgery, only T2 (3/5) and T3 (4/7) patients underwent a second operation for a recurrence. Overall survival at 42 months was 62.5% (T1, 100%; T2, 80%; T3, 28.5%)

  10. Phosphorylation of chloroform soluble compounds in plasma membranes of human epidermoid carcinoma A431 cells

    International Nuclear Information System (INIS)

    This study investigated a possible role for the epidermal growth factor (EGF) receptor protein tyrosine kinase in phosphoinositide metabolism with plasma membrane vesicles from human epidermoid carcinoma (A431) cells. The authors found a novel chloroform-soluble product radiolabeled with [gamma-32P]ATP that did not migrate from the origin in the thin layer system designed to separate the phosphoinositides, appeared as a single band of Mr = 3500 on polyacrylamide gels in the presence of dodecyl sulfate, had an ultraviolet absorbance spectrum with a maximum at 275 nm and stained with Coomassie dye. Based on these properties this phosphorylation product is referred to as a proteolipid. The 32P label was not detected in phosphotyrosine [Tyr(P)], phosphoserine [Ser(P)] or phosphothreonine [Thr(P)] and was lost during acid or base hydrolysis. Phosphorylation of proteolipid was increased significantly by EGF, whereas phosphorylation of phosphatidic acid was decreased and labeling of phosphoinositides was unaffected. Thus, it appears that in A431 membranes the EGF receptor/kinase does not utilize phosphatidylinositol as a substrate, but does phosphorylate a membrane proteolipid

  11. Cisto assintomático em região da valécula: relato de caso / Asymptomatic vallecular cyst: case report / Quiste valecular asintomático: relato de caso

    Scientific Electronic Library Online (English)

    Yucel, Yuce; Sennur, Uzun; Ulku, Aypar.

    2013-10-01

    Full Text Available Paciente do sexo masculino, 56 anos, apresentou-se para excisão de glioblastoma intracraniano multiforme. Após ser rotineiramente monitorado, o paciente foi pré-oxigenado. Anestesia e paralisia foram induzidas com propofol (200 mg), fentanil (50 µg) e vecurônio (9 mg). Laringoscopia direta com lâmin [...] a Macintosh número 3 revelou um cisto pedunculado de 2x2 cm, que surgia do lado direito da valécula e impedia a intubação endotraqueal. Enquanto o paciente permanecia anestesiado, consultamos rapidamente um otorrinolaringologista e o cisto foi aspirado por uma seringa com agulha de calibre 22G sob laringoscopia direta. Aspiramos 10 cc de líquido. Intubação traqueal foi feita em seguida sem intercorrências com sonda de 9,0 aramada e com balão. Uma opção para a intubação com fibra óptica pode ser a aspiração cuidadosa do cisto para facilitar a intubação. Abstract in spanish Un paciente del sexo masculino, de 56 años, llegó para una resección de glioblastoma intracraneal multiforme. Posteriormente a la rutina de monitorización, el paciente fue pre-oxigenado. La anestesia y la parálisis se indujeron con propofol (200 mg), fentanilo (50 µg) y vecuronio (9 mg). La laringos [...] copia directa con lámina 3 Macintosh arrojó un quiste pedunculado de 2x2 cm que surgía al lado derecho de la valécula e impedía la intubación endotraqueal. Mientras el paciente permanecía anestesiado, consultamos rápidamente un otorrinolaringólogo y el quiste fue aspirado por una jeringa con una aguja calibre 22G bajo laringoscopia directa. Aspiramos 10 cc de líquido. La intubación traqueal se hizo enseguida sin intercurrencias con una sonda de 9,0 y un alambre en espiral y con balón. Una opción para la intubación con fibra óptica puede ser la aspiración cuidadosa del quiste para facilitar la intubación. Abstract in english A 56-year-old man presented himself for an intracranial glioblastoma multiforme excision. After being routinely monitored, he was preoxygenated. We induced anesthesia and paralysis with 200 mg propofol, 50 µg fentanyl and 9 mg vecuronium. Direct laryngoscopy with a Macintosh 3 blade revealed a 2x2 c [...] m cyst, pedunculated, arising from the right side of the vallecula preventing the endotracheal intubation. While the patient remained anesthetized, we urgently consulted an otolaryngologist and aspirated the cyst with a 22-gauge needle and syringe under direct laryngoscopy. We aspirated 10 cc of liquid content. This was followed by an uneventful tracheal intubation with a 9.0 enforced spiral cuffed tube. An alternative to fiberoptic intubation may be careful cyst aspiration to facilitate the intubation.

  12. Metastatic Testicular Choriocarcinoma: A Rare Cause of Upper GI Bleeding.

    Science.gov (United States)

    Lowe, Kirsty; Paterson, Jacqueline; Armstrong, Sharon; Walsh, Shaun; Groome, Max; Mowat, Craig

    2015-10-01

    We present a case of upper gastrointestinal bleeding in an otherwise healthy 18-year-old man who presented with melena. Endoscopy revealed an ulcerated mass in the stomach and pathology confirmed this to be a malignant, poorly differentiated choriocarcinoma. Further imaging showed a left testicular mass with evidence of pulmonary, gastric, and brain metastases, and blood tests revealed an hCG level of 32,219 U/L. He was diagnosed with advanced metastatic testicular choriocarcinoma and underwent intensive induction chemotherapy and an orchidectomy. Metastatic testicular choriocarcinoma is a rare cause of gastrointestinal bleeding. PMID:26504875

  13. Value of bone scanning in patients with testicular tumors

    International Nuclear Information System (INIS)

    In order to evaluate the potential of routine bone scanning in the follow-up investigation of patients with testicular tumors, 238 scans from 124 patients were retrospectively analysed. 155/238 (65%) of all bone scans were normal. Benign lesions of arthrotic and traumatic origin were seen in 75 (32%) patients. Only 6 sceletal scans were suspicious but X-ray findings excluded metastatic lesions. From 1979 to 1986 no bone metastases from testicular tumors were seen in any patient. Thus, sceletal scintigraphy is not suitable for routine performance in follow-up examinations of patients with testicular tumors. (orig.)

  14. Evaluation of Doppler Indices in Varicocele-Related Testicular Atrophy

    OpenAIRE

    Masoud Nemati; Abolhassan Shakeri Bavil

    2010-01-01

    Background/Objective: Varicocele is a well-recognized cause of decreased testicular function and atrophy and occurs in approximately 15-20% of all men and 40% of infertile men. The aim of this study was to evaluate varicocele-related testicular atrophy with Duplex sonography. "nPatients and Methods: Fifty patients (mean age 24±7.43) with testicular atrophy due to varicocele were included in the study during 2005-2008."nResults: Echogenicity of the atrophic testis was homo...

  15. Metástasis testicular metacrónica secundaria a adenocarcinoma renal de células claras / Metachronic testicular metastasis secondary to clear cell renal adenocarcinoma

    Scientific Electronic Library Online (English)

    Roberto, Llarena Ibarguren; Jorge, García-Olaverri Rodríguez; Igor, Azurmendi Arin; Ivan, Olano Grasa; Carlos, Pertusa Peña.

    2008-05-01

    Full Text Available Objetivo: Presentar un caso de metástasis inusual en testículo de origen renal. Método: Paciente de 57 años afecto y en tratamiento por un cáncer renal derecho diseminado que durante su evolución con terapia médica aparecieron metástasis óseas y un nódulo doloroso en polo superior testicular derecho [...] , que obligó a cirugía, con resultado de metástasis de adenocarcinoma de células claras. Resultado: A los 6 meses el paciente sigue en tratamiento con sorafenib oral sin que se hayan manifestado más implantes metastáticos. Conclusiones: Los tumores secundarios metástasicos en testes suponen menos del 1% del total de tumores testiculares. En pacientes en la 5ª y 6ª década, sobre todo afectos de otras neoplasias, las masas testiculares acostumbran a ser implantes metastáticos. El origen más frecuente es el prostático. Abstract in english Objective: To report one case of unusual testicular metastasis from a renal origin. Methods: 57-year-old patient with disseminated right renal cancer under treatment who presented bone metastasis and a painful nodule in the upper pole of the right testicle during his follow-up with medical therapy, [...] making surgery necessary. The pathology result was clear cell adenocarcinoma. Results: Six months later the patient continues under oral Sorafenib without evidence of new metastatic implants. Conclusions: Testicular secondary metastatic tumors account for less than 1% of old testicular tumors. In patients in the fifth and sixth decades, mainly if they are affected by other neoplasias, testicular masses use to be metastatic implants. The most frequent origin is prostate.

  16. HISTOLOGIA TESTICULAR HUMANA COMPARADA, ADULTO JOVEN Y SENIL HUMAN TESTICULAR HISTOLOGY IN YOUNG AND SENILE MEN

    OpenAIRE

    Héctor Rodríguez; Paulina Salazar; Nadia Schmidt; Patricia Torres; Enrique Ossandón

    1999-01-01

    In general, sperm production decreases with advanced age in men. Therefore the present work compares the histology and cellularity of aging human testis with that of a young adult. Gonads from three patients 69 years old and testis from a young subject (aged 25 years) were examined after histological standard techniques (PAS-Haematoxyline). Histological, morphometric and cell counting analyses of testicular sections revealed that the seminiferous tubules of senile patients were of smaller dia...

  17. VARIACIONES DEL FUNCIONAMIENTO TESTICULAR Octopus mimus ADULTOS TESTICULAR FUNCTION VARIATIONS IN ADULT Octopus mimus

    OpenAIRE

    Alberto Olivares Paz; Eduardo Bustos-Obregón; Vivian Castillo Alvarez; Oscar Zúñiga Romero

    2003-01-01

    Octopus mimus macho madura precozmente. En general, sobre 200 g son maduros y permanecen en dicha condición hasta la muerte. En consideración a que no hay antecedentes de la fisiología testicular de los machos adultos, fueron estudiadas la función gamética mediante análisis histológico de los túbulos seminíferos y la función endocrina, cuantificando en el testículo, progesterona y testosterona, en conjunto con el crecimiento y funcionalidad de los órganos blancos del andrógeno. Se detectaron ...

  18. Re-irradiation in stereotactic conditions and cetuximab for local relapses of epidermoid carcinoma of head and neck; Reirradiation en conditions stereotaxiques et cetuximab pour des recidives locales de carcinome epidermoide de la tete et du cou

    Energy Technology Data Exchange (ETDEWEB)

    Vasseur, F.; Comet, B.; Faivre-Pierret, M.; Coche-Dequeant, B.; Degardin, M.; Lefebvre, J.L.; Lacornerie, T.; Lartigau, E. [Departement universitaire de radiotherapie, centre Oscar Lambret, 59 - Lille (France); Universite Lille-2, 59 (France)

    2010-10-15

    The authors report a work aimed at assessing the feasibility and toxicity of a re-irradiation treatment in stereotactic conditions using CyberKnife and cetuximab in the case of local relapses of epidermoid cancers of the ORL sphere. Thirty three patients have been submitted to this treatment between June 2007 and April 2009. Although six patients died by six months, this treatment seems to be a good alternative, and presents an acceptable short-term toxicity. Further studies are needed to compare this technique to other therapeutic techniques, and to assess the risk of long term complications. Short communication

  19. Quistes de los maxilares en niños: Un analisis clínico / Cystic lesions of the jaws in children: A clinic analysis

    Scientific Electronic Library Online (English)

    Gustavo, Pina Godoy; Éricka Janine, Dantas da Silveira; Manuel Antonio, Gordón-Núñez; Lélia Maria, Guedes Queiroz; Daniela, Medeiros Dantas Gomes.

    2007-12-01

    Full Text Available Objetivo: Realizar uma avaliação epidemiológica dos cistos odontogênicos em pacientes de 0 a 14 años de edad, verificando quais são as lesões de mayor incidência entre estas idades. Métodos: Foram avaliadas 100 fichas histopatológicas de lesões diagnosticadas como cistos de natureza odontogênica, en [...] fatizando as características clínicas (gênero, idade, tipo de lesão cística, localização anatômica e tamanho da lesão) e radiográficas. Resultados: Foi observado que o gênero masculino, com idade média de 9,78 anos, assim como as regiões posterior de mandíbula e anterior da maxila foram mais comprometidos. O cisto dentígero foi a lesão mais comum, seguida d cisto radicular. Observou-se, além disso, que na amostra avaliada o aspecto radiográfico unilocular e as lesões assintomáticas foram as mais freqüentes. Conclusões: Foi concluído que é muito importante realizar este tipo de estudos, uma vez que, através deles podemos conhecer a freqüência e incidência de diversas lesões, principalmente em pacientes pediátricos, nos quais pouco se conhece sobre a prevalência das lesões císticas dos maxilares. Abstract in spanish Objetivo: Realizar una evaluación epidemiológica de los quistes odontogénicos en pacientes de 0 a 14 años de edad, verificando cuales son las lesiones de mayor incidencia entre estas edades. Métodos: Fueron evaluadas 100 fichas histopatológicas de lesiones diagnosticadas como quistes de naturaleza o [...] dontogénica, enfatizando las características clínicas (género, edad, tipo de lesión quística, localización anatómica y tamaño de la lesión) y radiográficas. Resultados: Fue observado que el género masculino, con edad media de 9,78 años, así como las regiones posterior de mandíbula y anterior de la maxila fueron más comprometidos. El quiste dentígero fue la lesión más común, seguida del quiste radicular. Se observó además, que en la muestra evaluada el aspecto radiográfico unilocular y las lesiones asintomáticas fueron las más frecuentes. Conclusiones: Se concluyó que es muy importante realizar éste tipo de estudios, una vez que, a través de ellos podemos conocer la frecuencia e incidencia de diversas lesiones, principalmente en pacientes pediátricos, en los cuales poco se conoce sobre la prevalencia de las lesiones quísticas de los maxilares. Abstract in english Objective: To realize an epidemiologic survey of odontogenic cysts in patients from 0 to 14 years old in order to find out the most prevalent lesions of each age period. Methods: 100 histopathologic files of lesions diagnosed as cysts of odontogenic origin were retrieved emphasing their clinic (cyst [...] ic lesion pattern, gender, age, anatomical site and lesion lenght) and radiographic features, which the surgical specimens were forwarded for the Oral Pathology Service of UFRN. Results: It could be identified that either the male gender, with an age average of 9,78 years, or the mandible posterior and the anterior maxilla region were more involved. Dentigerous cyst was the most prevalent lesions, followed by the radicular cyst. Moreover, a unilocular radiolucence and asymptomatic lesions were more common in the sample. Conclusions: To sum up, it can be infered the outstanding relevance of studies like the present since that it is through than that it can be reached the knownlodge of the frequence and incidence of several lesions, especially in paediatric patients inasmuch as the few knownlodge of the cystic lesion prevalence in their jaws.

  20. Quiste gigante de ovario y mioma uterino. Presentación de un caso Giant ovarian cyst and uterine myoma. A case report

    Directory of Open Access Journals (Sweden)

    Carlos Antonio Sánchez Portela

    2012-10-01

    Full Text Available Se presenta un caso de quiste gigante del ovario, en una paciente de 30 años de edad, que fue atendida por el Servicio de Ginecología del Hospital Provincial de Inhambane, en el año 2010, por un aumento de tamaño en el abdomen. Se realizaron los estudios clínicos y ultrasonográficos. Se confirmó a través de una laparotomía exploradora una tumoración quística gigante del ovario con dimensiones extraordinarias y un mioma uterino, lo que es poco frecuente en la actualidad. En el estudio anatomopatológico se comprobó el diagnóstico de cistoadenoma seroso del ovario.A 30-year old patient presenting a giant ovarian cyst was attended at Gynecology service in the Provincial Hospital of Inhambane in 2010, the patient complained of abdominal distension. Clinical and ultrasonographic studies were completed. An exploratory laparotomy confirmed a giant ovarian cyst having odd dimensions and uterine myoma, not frequently found in present times. Pathological studies proved a serous cystadenoma of the ovary.

  1. Quiste gigante de ovario y mioma uterino. Presentación de un caso / Giant ovarian cyst and uterine myoma. A case report

    Scientific Electronic Library Online (English)

    Carlos Antonio, Sánchez Portela; Adonis, García Valladares; Carmen Juana, Sánchez Portela.

    2012-10-01

    Full Text Available Se presenta un caso de quiste gigante del ovario, en una paciente de 30 años de edad, que fue atendida por el Servicio de Ginecología del Hospital Provincial de Inhambane, en el año 2010, por un aumento de tamaño en el abdomen. Se realizaron los estudios clínicos y ultrasonográficos. Se confirmó a t [...] ravés de una laparotomía exploradora una tumoración quística gigante del ovario con dimensiones extraordinarias y un mioma uterino, lo que es poco frecuente en la actualidad. En el estudio anatomopatológico se comprobó el diagnóstico de cistoadenoma seroso del ovario. Abstract in english A 30-year old patient presenting a giant ovarian cyst was attended at Gynecology service in the Provincial Hospital of Inhambane in 2010, the patient complained of abdominal distension. Clinical and ultrasonographic studies were completed. An exploratory laparotomy confirmed a giant ovarian cyst hav [...] ing odd dimensions and uterine myoma, not frequently found in present times. Pathological studies proved a serous cystadenoma of the ovary.

  2. Type II intrapancreatic choledochal malignant cyst in adults: duodenopancreatectomy / Quiste de colédoco tipo II intrapancreático del adulto malignizado: duodenopancreatectomía

    Scientific Electronic Library Online (English)

    Miguel Ángel, Jiménez-Ballester; Victoriano, Soria-Aledo; Juan Gervasio, Martín-Lorenzo; José Ramón, Olalla-Muñoz; Alberto, Giménez-Bascuñana; Eduardo, Alcaraz-Mateos; José Luis, Aguayo-Albasini.

    2014-03-01

    Full Text Available Presentamos el caso de una paciente de 62 años que ingresó de urgencias por pancreatitis aguda leve. En las pruebas de imagen se observó una lesión sólido-quística en la cabeza de páncreas comunicante con la vía biliar distal, y se diagnosticó quiste de colédoco tipo II de Todani con degeneración ne [...] oplásica en su interior confirmada tras una biopsia por punción en una ecoendoscopia. La paciente fue tratada con una duodenopancreatectomía cefálica con intención curativa. Abstract in english A 62-year-old female patient was admitted for abdominal pain and vomiting. Imaging tests revealed a solid-cystic lesion at the head of the pancreas communicating with the distal bile duct. A Todani type II choledochal cyst was diagnosed with neoplastic degeneration after cytological diagnosis with e [...] ndoscopic ultrasound-guided puncture. The patient was treated with a cephalic duodenopancreatectomy with curative intention.

  3. Tratamiento de un quiste hidatídico en un paciente con abdomen agudo. Comunicación de un caso y revisión bibliográfica

    Directory of Open Access Journals (Sweden)

    Luis Cruz Benítez

    2009-01-01

    Full Text Available Mujer de 45 años edad que ingresó al servicio de urgencias del Hospital General Dr. Darío Fernández Fierro (ISSSTE con dolor abdominal de seis meses de evolución, de intensidad leve al inicio hasta hacerse incapacitante, y fiebre. Se efectuaron exámenes de laboratorio y gabinete protocolarios de abdomen agudo. El ultrasonido abdominal mostró imágenes quísticas hepáticas en el lóbulo izquierdo. Se solicitó el estudio tomográfico abdominal para delimitar la ubicación y tamaño de las lesiones, y hacer diagnóstico diferencial con otras lesiones ocupantes del hígado. Ante la persistencia del cuadro doloroso abdominal y la sospecha de posibles complicaciones secundarias, se decidió la intervención quirúrgica programada. Se realizó laparotomía abdominal exploradora, con hallazgos transoperatorios de quistes de características hidatídicas, por lo que decidió efectuarse la resección de los mismos. El diagnóstico de enfermedad hidatídica hepática se confirmó por los estudios de imagenología, hallazgos transoperatorios, estudios citológicos e histopatológicos, y pruebas serológicas.

  4. Quiste gigante de uraco en el adulto / The giant cyst of urachus present in the adult patient

    Scientific Electronic Library Online (English)

    Radamés Isaac, Adefna Pérez; Armando, Leal Mursulí; Francoise, Izquierdo Lara; Nélida, Ramos Díaz; Juan, Castellanos González; Juan Francisco, Rodríguez Reyes.

    2009-06-01

    Full Text Available El quiste de uraco es una anomalía congénita que se incluye entre las lesiones originadas por la persistencia total o parcial de restos de este conducto. Se diagnostica principalmente durante la infancia y su complicación principal es la infección. Presentamos el caso de adulto con una tumoración ab [...] dominal gigante quística, diagnosticada como de origen uracal y tratada quirúrgicamente. Se hace una revisión del tema, con énfasis en los aspectos principales del tratamiento de la enfermedad. Abstract in english The urachus cyst is a congenital anomaly included among lesions originated by local or partial resistance of this duct. Is mainly diagnosed during infancy and its main complication is the infection. Authors present the case of an adult patient presenting with a cystic giant abdominal tumor, diagnose [...] d as of urachal origin and treated by surgery. This matter is reviewed emphasizing on main features of disease treatment.

  5. Resección del quiste tirogloso con preservación del hueso hioides / Resection of thyroglossal cyst with preservation of the hyoid bone

    Scientific Electronic Library Online (English)

    Gabriel, Sánchez; Elkin, Cabrera.

    2014-03-01

    Full Text Available Introducción. El quiste del conducto tirogloso representa la lesión congénita más frecuente del cuello, con una incidencia de 7 % de la población general. La presentación típica consiste en una masa en la línea media, entre el foramen ciego y la glándula tiroides, que asciende con la deglución o pro [...] trusión de la lengua. Tradicionalmente, se ha recomendado la remoción del quiste mediante el procedimiento de Sistrunk. Se describe una modificación de la técnica quirúrgica, preservando el cuerpo del hioides. El objetivo del presente estudio fue evaluar la frecuencia de complicaciones perioperatorias y de recidiva después del procedimiento quirúrgico modificado. Materiales y métodos. Se hizo un análisis retrospectivo de una cohorte de pacientes sometidos entre marzo de 2003 y marzo de 2011 a la resección quirúrgica del quiste del conducto tirogloso con el procedimiento modificado. Las intervenciones fueron practicadas por un cirujano de cabeza y cuello de la Fundación Cardioinfantil (Bogotá). Resultados. En el estudio se incluyeron 43 pacientes que cumplían los criterios de inclusión. La mediana de seguimiento fue de 11 meses y la tasa de complicaciones fue 6,9 % (n=3). Se presentaron dos granulomas a cuerpo extraño y un mucocele, este último considerado como una recidiva (2,3 %). Discusión. En el presente estudio no se encontró un incremento en la frecuencia de complicaciones perioperatorias cuando se reseca el quiste del conducto tirogloso con la técnica modificada. La recurrencia de la enfermedad está en el rango de lo reportado en la literatura científica, por lo que consideramos que el procedimiento quirúrgico propuesto puede ser una opción segura y viable. Abstract in english Introduction: Thyroglossal duct cyst is the most common congenital anomaly of the neck, with an overall incidence of 7%. The typical presentation is a mass in the midline between the foramen cecum and the thyroid gland, which moves with swallowing or protrusion of the tongue. Traditionally it has be [...] en recommended the removal of the cyst by the Sistrunk procedure. The authors describe a modified surgical technique that preserves the hyoid bone. The aim of our study was to evaluate the rate of perioperative complications and recurrences after this modified surgical procedure. Materials and methods: We conducted a retrospective analysis of a cohort patients undergoing resection of thyroglossal duct cyst with the modified surgical procedure between March 2003 and March 2011. Surgery was performed by a head and neck surgeon of Foundation Cardioinfantil, Bogotá. Results: 43 patients who met the inclusion criteria were included in the study. Median follow-up was 11 months and the rate of complications was 6.9% (n = 3). There were 2 foreign body granulomas and one mucocele, which was considered a recurrence (2.3%). Discussion: We did not find an increase in the rate of perioperative complications with the modified surgical technique. Recurrence of the disease is similar to the data reported in the literature and we believe that the proposed surgical procedure can be a safe and viable option.

  6. Quiste gigante de uraco en el adulto The giant cyst of urachus present in the adult patient

    Directory of Open Access Journals (Sweden)

    Radamés Isaac Adefna Pérez

    2009-06-01

    Full Text Available El quiste de uraco es una anomalía congénita que se incluye entre las lesiones originadas por la persistencia total o parcial de restos de este conducto. Se diagnostica principalmente durante la infancia y su complicación principal es la infección. Presentamos el caso de adulto con una tumoración abdominal gigante quística, diagnosticada como de origen uracal y tratada quirúrgicamente. Se hace una revisión del tema, con énfasis en los aspectos principales del tratamiento de la enfermedad.The urachus cyst is a congenital anomaly included among lesions originated by local or partial resistance of this duct. Is mainly diagnosed during infancy and its main complication is the infection. Authors present the case of an adult patient presenting with a cystic giant abdominal tumor, diagnosed as of urachal origin and treated by surgery. This matter is reviewed emphasizing on main features of disease treatment.

  7. Surveillance for Stage I Nonseminoma Testicular Cancer

    DEFF Research Database (Denmark)

    Daugaard, Gedske; Gundgaard, Maria Gry; Mortensen, Mette Saksø; Agerbæk, Mads; Holm, Niels Vilstrup; Rørth, Mikael; von der Maase, Hans; Christensen, Ib Jarle; Lauritsen, Jakob

    2014-01-01

    PURPOSE: To describe treatment results in a large cohort with stage I nonseminoma germ cell cancer (NSGCC) treated in a surveillance program. PATIENTS AND METHODS: From January 1, 1984, to December 31, 2007, 1,226 patients with stage I NSGCC, including high-risk patients with vascular invasion......, were observed in a surveillance program. RESULTS: The relapse rate after orchiectomy alone was 30.6% at 5 years. Presence of vascular invasion together with embryonal carcinoma and rete testis invasion in the testicular primary identified a group with a relapse risk of 50%. Without risk factors, the...... relapse risk was 12%. Eighty percent of relapses were diagnosed within the first year after orchiectomy. The median time to relapse was 5 months (range, 1 to 308 months). Early relapses were mainly detected by increase in tumor markers, and late relapses were detected by computed tomography scans...

  8. ABSCESSO TESTICULAR EM HAMSTER: RELATO DE CASO

    Directory of Open Access Journals (Sweden)

    R. M. Santos

    2012-12-01

    Full Text Available The Hamster, rodent originating from the Middle East, is a species studied along with other laboratory animals as experimental models in scientific papers and currently is also created as a pet, by virtue of being docile, easy to handle and require little space for survival. The suppurative processes in domestic animals are relatively frequent. Due to infectious diseases or purulent course of aggressiveness of the environment in which they live. The habit of storing food in the cheeks with sharp edges can injure the skin and often cause abscesses in this species. However, other lesions may lead to suppuration, diseases such as testicular tumor or no tumor or not produced by damage in the skin, leading to tumescence (VITAL et al., 2007. This article reports a case of a hamster treated at the Veterinary Hospital of FAFRAM with clinical history of discomfort, anorexia and frequent licking of the scrotum. On clinical examination it was found by aspiration of purulent secretions and the presence of large numbers of polymorphonuclear cells on cytology, diagnosed with testicular abscess. The animal was taken to the operating room where was performed conventional bilateral orchiectomy and total excision of the abscess by opening the tunica vaginalis and ligation of the spermatic cord. Postoperative care included antibiotic therapy with enrofloxacin and use of an anti-inflammatory meloxicam. After ten days the stitches were removed, the wound was healing satisfactorily and the animal was in good health.O Hamster, roedor originário do Oriente Médio, é uma espécie estudada juntamente com outros animais de laboratório como modelo experimental em trabalhos científicos e, atualmente, também é criado como animal de companhia, em virtude de ser dócil, de fácil manuseio e necessitar de pequeno espaço para sobrevivência. Os processos supurativos nos animais domésticos são relativamente frequentes. Em decorrência de doenças infectocontagiosas de curso purulento ou da agressividade do meio em que vivem. No hamster, o hábito de armazenar alimentos com extremidades pontiagudas nas bochechas, pode lesionar a pele e comumente causar abscessos nesta espécie. No entanto, outras lesões podem levar à supuração, tais como afecções testiculares tumorais ou não tumorais produzidas ou não por lesão de continuidade da pele, levando à intumescência (VITAL et al., 2007. Este trabalho relata um caso de um hamster atendido no Hospital Veterinário da FAFRAM com histórico clínico de inquietação, anorexia e lambedura frequente da região escrotal. Ao exame clínico constatou-se através de punção aspirativa secreção de aspecto purulento e presença de grande quantidade de polimorfonucleares à citologia, sendo diagnosticado abscesso testicular. O animal foi encaminhado para o centro cirúrgico onde foi realizado orquiectomia bilateral convencional e exérese total do abscesso, através de abertura da túcnica vaginal e ligadura do funículo espermático. O pós-operatório incluiu antibioticoterapia com enrofloxacina e utilização de um antiinflamatório meloxican. Após dez dias os pontos foram removidos, a cicatrização da ferida cirúrgica ocorreu de maneira satisfatória e o animal apresentava-se em bom estado de saúde.

  9. [Testicular and paratesticular tumors in children].

    Science.gov (United States)

    Fabbro, M A; Costa, L; Cimaglia, M L; Donadio, P; Spata, E

    1995-01-01

    Testis tumors in children occur infrequently and exibit differences in their histopathology, clinical behaviour and therapy from their adult counterparts. From 1979 to 1994, 17 children and adolescent with testicular tumors were treated at the Pediatric Surgical Department of Vicenza Regional Hospital. Paratesticular rabdomiosarcoma were present in 3 cases, 4 patients had embrional carcinoma, 1 Sertoli cell tumor, 2 Leydig cell gonadal stromal tumor, and leukemic infiltrates of the testis were clinically evident in 7 patients. We report our clinical series and discuss in relation to clinical characteristic, histopathology and therapy and conclude that the improved survival during the past decade is attributable to better diagnostic imaging thecniques, the availability of serum tumor markers to monitor disease activity and more effective chemotherapy. PMID:8668584

  10. Ontogenesis of testicular function in humans.

    Directory of Open Access Journals (Sweden)

    Ga??lle Angenard

    2010-01-01

    Full Text Available The two major functions of the testis, steroidogenesis and gametogenesis, take place during fetal life. These two functions have been extensively studied in rodents and adult humans. However, their onset during fetal life is poorly documented in humans. In the first part of this work we presented both our experimental data and some data of literature concerning the development of the human fetal testis. In the second part of this article, using the organ culture system we previously developed, we have investigated the regulations or perturbations of fetal testis development both in rodent and human models. Our findings provide important insight into the potential role of exposure to environmental pollutants (physical factors, in particular ionizing radiation, cadmium and endocrine disruptors such as phthalates during fetal testicular development and their potential deleterious effects on male fertility in adulthood. Our results highlight the specificity of the human model compared with rodent models.

  11. Radiation therapy of testicular non-seminomas

    Energy Technology Data Exchange (ETDEWEB)

    Van der Werf-Messing, B.; Hop, W.C.J.

    1982-02-01

    The prognosis of 121 patients with a non-seminoma testicular tumor MTI or MTU was assessed. The clinical lymph node involvement and the T-category of the primary had a significant bearing on prognosis, which is completely determined by pulmonary relapse. The low-risk group (9% pulmonary relapse, all curable) is characterized by a primary category T/sub 1/ or T/sub 2/ with negative lymphangiography. The percentage of favorable patients is significantly higher if there is malignant teratoma intermediate (MTI) rather than malignant teratoma undifferentiated (MTU) histology. Systematic use of tumor markers (..beta../sub 1/-HCG and alpha fetoprotein), and perhaps an assessment of vascular invasion in the primary, might be useful to identify those patients in the unfavorable group who might benefit from elective chemotherapy.

  12. Clinical case: Testicular cancer with metastases (Caso clínico: Cáncer testicular con metástasis

    Directory of Open Access Journals (Sweden)

    Valderrama-Gómez Ricardo Alfredo

    2011-11-01

    Full Text Available Testicular cancer is the most common malignancy in men aged15-45 years. As a result of therapeutic advances in recent decadesand the integration of multimodal treatment, testicular cancer isnowadays one of the most curable malignancies. Non-seminomaGerminal cells tumor type includes embryonic carcinoma, choriocarcinoma,teratoma and yolk sac tumor. Despite of the long-termsurvival is favorable, multimodal treatment of NSGCT is constantlyevolving and incorporating new paradigms.It is described a patient in working age and fertile, who presents aclinical picture of +/- 2 years of evolution, presenting a left testicularpainless mass, the which increased progressively associated toweight lost. He presented abdominal pain without fever or historyof irritative urinary symptoms. This pathology is rare in our context,seen 3-4 cases per year in Viedma Hospital, with an incidenceof 0,8 per 100000 inhabitants/year in Bolivia, so it is important topresent it, so it can be diagnosed in less advanced stages. -RESUMEN: El cáncer testicular es la patología maligna más común en los hombresentre 15-45 años. Como resultado de los adelantos terapéuticosen las últimas décadas y la integración del tratamiento multimodal,el cáncer testicular es ahora una de las neoplasias más curables. ElTumor de Células Germinales de tipo No Seminoma (NSGCT, porsus siglas en ingles incluye el carcinoma embrionario, el coriocarcinoma,el teratoma y el tumor del saco vitelino. A pesar de ser favorablela supervivencia a largo plazo, el diagnóstico generalmentees un estadio tardio, por su presentación inicial asintomática.Ahora describimos a un paciente en edad laboral y fértil, el cualse caracterizo por un cuadro clínico de +/- 2 años de evolución,presentando una masa testicular izquierda, no dolorosa, que aumentóde volumen progresivamente asociada a pérdida de peso, dolorabdominal, sin alzas térmicas, ni antecedentes de sintomatologíairritativa urinaria.Esta patología es poco frecuente en nuestro medio, observándoseaproximadamente 3-4 casos por año en el Hospital Clínico Viedma,con una incidencia de 0.8 por cada 100.000 habitantes/año en Bolivia.Por lo que creemos es importante la presentación del mismo,para que no se lo subdiagnostique y pueda ser diagnosticado enestadio menos avanzados.

  13. Tratamiento quirúrgico de pacientes con quistes de inclusión epidérmica / Surgical treatment of patients with epidermal inclusion cysts

    Scientific Electronic Library Online (English)

    José Manuel, Díaz Fernández; Alejandro Francisco, Agüero Díaz; Manuel, Fonseca Labaut; Carlos Juan, Puig González; Anyi Lucía, Díaz Cardero.

    2014-06-01

    Full Text Available Se realizó un estudio prospectivo, longitudinal y aleatorizado de 29 pacientes con quiste de inclusión epidérmica en la región cervicofacial, no infectados, atendidos en el Servicio de Cirugía Maxilofacial del Hospital Clinicoquirúrgico Docente "Saturnino Lora Torres" de Santiago de Cuba, desde juni [...] o de 2011 hasta noviembre de 2012, tratados quirúrgicamente mediante los métodos de incisión lineal mínima o excisión en W, con vistas a comparar los resultados de ambos procederes. Se obtuvo que el tiempo operatorio promedio fue más corto en el grupo de incisión lineal mínima y que los quistes que medían entre menos de 1 y hasta 2 cm, localizados en las unidades estéticas faciales de mayor exigencia, eran mejor tratados con dicho método, lo cual produjo mejores resultados y un índice recurrencia no significativo en relación con la excisión en W Abstract in english A prospective, longitudinal and randomized study of 29 patients with epidermal inclusion cysts in the cervicofacial region, not infected, assisted in the Maxillofacial Surgery Service of "Saturnino Lora Torres" Teaching Clinical Surgical Hospital in Santiago de Cuba was carried out from June, 2011 t [...] o November, 2012, surgically treated by means of the methods of minimal lineal incision or W excision, with the aim of comparing the results of both procedures. It was obtained that the average surgical time was shorter in the group of minimal lineal incision and that the cysts fluctuating from less than 1 cm and up to 2 cm, located in the facial aesthetic units of greater demand, were better treated with this method, what produced better results and a non significant recurrence value in relation to the W excision

  14. Identificación de células proliferativas en quistes de Taenia solium / Identification of proliferating cells in Taenia solium cysts

    Scientific Electronic Library Online (English)

    Miguel Ángel, Orrego-Solano; Carla, Cangalaya; Theodore E, Nash; Cristina, Guerra-Giraldez.

    2014-10-01

    Full Text Available Los neoblastos son células totipotentes, únicas responsables de la proliferación y maduración de tejidos en platelmintos de vida libre. Células similares se han aislado en platelmintos parásitos como Echinococcus. Taenia solium causa la teniasis humana (intestinal) y la cisticercosis en humanos y ce [...] rdos. La infección del cerebro con larvas (quistes) de T. solium resulta en neurocisticercosis, hiperendémica en el Perú; su tratamiento se asocia a síntomas neurológicos graves. La capacidad proliferativa y el desarrollo de los estadios de T. solium aún no se describen, y no se ha caracterizado los neoblastos de este parásito. Se buscó células proliferativas en quistes de T. solium colectados de un cerdo infectado, que fueron identificadas al replicarse e incorporar el nucleótido bromodesoxiuridina, detectado con un anticuerpo monoclonal. Una línea celular estable de neoblastos sería útil para estudios sistemáticos in vitro sobre eficacia de drogas y sobre la biología de T. solium. Abstract in english Neoblasts are totipotent cells, solely responsible for the proliferation and maturation of tissues in free-living flatworms. Similar cells have been isolated from parasitic flatworms such as Echinococcus. Taenia solium causes human taeniasis (intestinal) and cysticercosis in humans and pigs. Brain i [...] nfection with larvae (cysts) of T. solium results in neurocysticercosis which is hyperendemic in Peru, and its treatment is associated with serious neurological symptoms. The proliferative capacity and development stages of T. solium have not been described and the neoblasts of this parasite have not been characterized We looked for cell proliferation in T. solium cysts collected from an infected pig, which were identified when replicating and incorporating bromodeoxyuridine nucleotide detected with a monoclonal antibody. A stable cell line of neoblasts would be useful for systematic in vitro studies on drug efficacy and the biology of T. solium.

  15. Identificación de células proliferativas en quistes de Taenia solium / Identification of proliferating cells in Taenia solium cysts

    Scientific Electronic Library Online (English)

    Miguel Ángel, Orrego-Solano; Carla, Cangalaya; Theodore E., Nash; Cristina, Guerra-Giraldez.

    2014-12-01

    Full Text Available Los neoblastos son células totipotentes, únicas responsables de la proliferación y maduración de tejidos en platelmintos de vida libre. Células similares se han aislado en platelmintos parásitos como Echinococcus. Taenia solium causa la teniasis humana (intestinal) y la cisticercosis en humanos y ce [...] rdos. La infección del cerebro con larvas (quistes) de T. solium resulta en neurocisticercosis, hiperendémica en el Perú; su tratamiento se asocia a síntomas neurológicos graves. La capacidad proliferativa y el desarrollo de los estadios de T. solium aún no se describen, y no se ha caracterizado los neoblastos de este parásito. Se buscó células proliferativas en quistes de T. solium colectados de un cerdo infectado, que fueron identificadas al replicarse e incorporar el nucleótido bromodesoxiuridina, detectado con un anticuerpo monoclonal. Una línea celular estable de neoblastos sería útil para estudios sistemáticos in vitro sobre eficacia de drogas y sobre la biología de T. solium. Abstract in english Neoblasts are totipotent cells, solely responsible for the proliferation and maturation of tissues in free-living flatworms. Similar cells have been isolated from parasitic flatworms such as Echinococcus. Taenia solium causes human taeniasis (intestinal) and cysticercosis in humans and pigs. Brain i [...] nfection with larvae (cysts) of T. solium results in neurocysticercosis which is hyperendemic in Peru, and its treatment is associated with serious neurological symptoms. The proliferative capacity and development stages of T. solium have not been described and the neoblasts of this parasite have not been characterized We looked for cell proliferation in T. solium cysts collected from an infected pig, which were identified when replicating and incorporating bromodeoxyuridine nucleotide detected with a monoclonal antibody. A stable cell line of neoblasts would be useful for systematic in vitro studies on drug efficacy and the biology of T. solium.

  16. Transverse testicular ectopia, a case report and review of literature

    Directory of Open Access Journals (Sweden)

    Moslemi, Mohammad Kazem

    2011-01-01

    Full Text Available Crossed testicular ectopia (CTE/transverse testicular ectopia (TTE is a rare but well known congenital anomaly, in which both gonads migrate toward the same hemiscrotum. It is usually associated with other abnormalities such as persistent Mullerian duct syndrome, true hermaphroditism, inguinal hernia, hypospadias, pseudohermaphroditism, and scrotal anomalies. About 100 cases of transverse testicular ectopia have been reported in published studies. We report a case of transverse testicular ectopia in an 8-month-old boy who presented with right inguinal hernia and nonpalpable left testis. On exploration, both testes were present in the right inguinal region. Bilateral orchiopexy was performed by crossing the left testis in the extra-peritoneal space and ipsilateral scrotal orchiopexy. The diagnosis could not be made preoperatively in most of reported cases.

  17. Reversible harmless interruption of testicular blood supply in the ram

    International Nuclear Information System (INIS)

    An effective method of interrupting testicular blood flow temporarily and repeatedly in the ram has been developed. Blockade of flow has been achieved mechanically by an inflatable occluder placed around the testicular artery at the level of the spermatic cord. The effect of the blockade on total testicular blood supply was investigated using Doppler flowmetry and a percutaneous Xenon-133 injection method. With both approaches, the blood flow changes after inflation or deflation of the occluders could be estimated satisfactorily. A substantial decrease of testicular blood flow was achieved in eight of the 10 testes with inflated occluders. However, there were indications that in the remaining two testes blockade of the arterial flow was not complete. After deflation of the occluders, blood flow was restored rapidly and completely in all testes. Macro- and microscopic examinations revealed no long-term damage to the testis after blood flow interruptions lasting 30 or 60 minutes

  18. Testicular germ cell tumor fungating through anterior abdominal wall

    OpenAIRE

    Ghosh, Indranil; Raina, V.

    2011-01-01

    Retroperitoneal lymph node metastases from testicular germ cell tumor are common, but fungation of such mass through the anterior abdominal wall is extremely rare. We report such a case which had a favorable response to chemotherapy.

  19. Multiple vascular anomalies involving testicular, suprarenal arteries and lumbar veins

    Directory of Open Access Journals (Sweden)

    P Jyothsna

    2012-01-01

    Full Text Available Testicular arteries arise from the abdominal aorta and the inferior suprarenal artery from the renal artery. There are reports about variant origin and course of these arteries. Accessory testicular artery is also a common finding but its providing origin to inferior suprarenal artery is an important observation. During a routine dissection of abdomen of approximately 55-year-old male cadaver, unique vascular abnormality was observed. On the left side, a common arterial trunk originating from abdominal aorta immediately branched to give rise to superior testicular and inferior suprarenal arteries, the former after a short course hooked by the left suprarenal vein. In addition, the left suprarenal vein, second left lumbar vein, and left testicular vein joined to form a common trunk which drained into the left renal vein. A sound knowledge of vascular variations in relation to the kidney and suprarenal gland is important to surgeons dissecting the abdominal cavity.

  20. Metachronous bilateral testicular germ cell tumors: Report of two cases

    Directory of Open Access Journals (Sweden)

    James Francis

    2009-01-01

    Full Text Available Metachronous bilateral testicular germ cell tumors is a rare known problem. However, no report of metachronus bilateralism was identified in the PubMed database published from India so far, where testicular cancer is relatively rare. We report the cases of two gentlemen. One had stage 1 nonseminomatous germ cell tumor (NSGCT at the age of 32 in 1990 and developed marker relapse on surveillance and had chemotherapy using cisplatin and etoposide for four cycles. He developed contralateral seminoma in the testis 13 years later. Another patient had left orchidectomy in 2003 for NSGCT, had adjuvant BEP for two cycles, and developed a contralateral testicular tumor 5 years later, which was also seminoma. As more patients with germ cell tumors are cured with chemotherapy, long-term problems become important. Contralateral testicular tumor is one of them. As it can be very late, many years of continued follow-up examination and patients? awareness are necessary.

  1. Male Infertility Might Signal Higher Odds of Testicular Cancer

    Science.gov (United States)

    ... nih.gov/medlineplus/news/fullstory_155748.html Male Infertility Might Signal Higher Odds of Testicular Cancer Abnormally ... men who underwent semen analysis as part of infertility treatment between 1996 and 2011. They were compared ...

  2. Review of photodynamic therapy with 5-methyl aminolevulinate in actinic keratosis, epidermoid carcinoma and basal cell carcinoma

    International Nuclear Information System (INIS)

    A bibliographic review was conduced on the use of 5-methyl aminolevulinate in dermatology, specifically in the treatment of actinic keratosis, epidermoid carcinoma and basal cell carcinoma. The basic fundamentals of photodynamic therapy are described. The preparation and method of use of photodynamic therapy with 5-methyl aminolevulinate (MAL-PDT) are detailed. The clinical studies that were realized with photodynamic therapy for the treatment of actinic keratosis, epidermoid carcinoma and basal cell carcinoma are mentioned. Different photo-inducible agents and other current therapeutic options of first-line are compared. The MAL-PDT has have the advantage of to present less side effects and the same have been more tolerable than liquid nitrogen and 5 fluorouracil. The MAL-PDT has been considered as an effective option for the treatment of Bowen's disease. Invasive epidermoid carcinoma has existed without evidence to support the routine use of this therapeutic. For superficial basal cell carcinoma, the MAL-PDT has presented a high cure rate and transient and manageable side effects in extensive and multiple lesions. The MAL-PDT has been an effective and safe treatment in patients with basal cell carcinoma, for those with less depth of 2mm. The MAL-PDT could play an important role in the field of prevention with immunosuppressed patients, particularly, those that have required transplant and its immunosuppression has been pharmacological. The use or not of the MAL-PDT, should be evaluated individually for each patient and to have suitable characteristics for each disease that was cited in this review. The photodynamic therapy with 5-methyl aminolevulinate has been a therapeutic modality of considerable economy, however, it should be evaluated in the context of number of inquiries and side effects that have offered other therapeutic modalities

  3. Adverse testicular effects of Botox® in mature rats

    Energy Technology Data Exchange (ETDEWEB)

    Breikaa, Randa M. [Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo (Egypt); Mosli, Hisham A. [Department of Urology, Faculty of Medicine, King Abdulaziz University, Jeddah (Saudi Arabia); Nagy, Ayman A. [Department of Pathology, Faculty of Medicine, King Abdulaziz University, Jeddah (Saudi Arabia); Department of Forensic Medicine and Toxicology, Faculty of Medicine, Tanta University, Tanta (Egypt); Abdel-Naim, Ashraf B., E-mail: abnaim.pharma@gmail.com [Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo (Egypt); Department of Pharmacology and Toxicology, Faculty of Pharmacy, King Abdulaziz University, Jeddah (Saudi Arabia)

    2014-03-01

    Botox® injections are taking a consistently increasing place in urology. Intracremasteric injections, particularly, have been applied for cryptorchidism and painful testicular spasms. Studies outlining their safety for this use are, however, scanty. Thus, the present study aimed at evaluating possible testicular toxicity of Botox® injections and their effect on male fertility. Mature rats were given intracremasteric Botox® injections (10, 20 and 40 U/kg) three times in a two-week interval. Changes in body and testes weights were examined and gonadosomatic index compared to control group. Semen quality, sperm parameters, fructose, protein, cholesterol and triglycerides contents were assessed. Effects on normal testicular function were investigated by measuring testosterone levels and changes in enzyme activities (lactate dehydrogenase-X and acid phosphatase). To draw a complete picture, changes in oxidative and inflammatory states were examined, in addition to the extent of connective tissue deposition between seminiferous tubules. In an attempt to have more accurate information about possible spermatotoxic effects of Botox®, flowcytometric analysis and histopathological examination were carried out. Botox®-injected rats showed altered testicular physiology and function. Seminiferous tubules were separated by dense fibers, especially with the highest dose. Flowcytometric analysis showed a decrease in mature sperms and histopathology confirmed the findings. The oxidative state was, however, comparable to control group. This study is the first to show that intracremasteric injections of Botox® induce adverse testicular effects evidenced by inhibited spermatogenesis and initiation of histopathological changes. In conclusion, decreased fertility may be a serious problem Botox® injections could cause. - Highlights: • Botox® injections are the trend nowadays, for both medical and non-medical uses. • They were recently suggested for cryptorchidism and testicular spasms. • This study outlines possible testicular adverse effects of these injections. • Botox® affected normal testicular function and physiology. • Infertility is a serious problem that Botox® injections could cause.

  4. Adverse testicular effects of Botox® in mature rats

    International Nuclear Information System (INIS)

    Botox® injections are taking a consistently increasing place in urology. Intracremasteric injections, particularly, have been applied for cryptorchidism and painful testicular spasms. Studies outlining their safety for this use are, however, scanty. Thus, the present study aimed at evaluating possible testicular toxicity of Botox® injections and their effect on male fertility. Mature rats were given intracremasteric Botox® injections (10, 20 and 40 U/kg) three times in a two-week interval. Changes in body and testes weights were examined and gonadosomatic index compared to control group. Semen quality, sperm parameters, fructose, protein, cholesterol and triglycerides contents were assessed. Effects on normal testicular function were investigated by measuring testosterone levels and changes in enzyme activities (lactate dehydrogenase-X and acid phosphatase). To draw a complete picture, changes in oxidative and inflammatory states were examined, in addition to the extent of connective tissue deposition between seminiferous tubules. In an attempt to have more accurate information about possible spermatotoxic effects of Botox®, flowcytometric analysis and histopathological examination were carried out. Botox®-injected rats showed altered testicular physiology and function. Seminiferous tubules were separated by dense fibers, especially with the highest dose. Flowcytometric analysis showed a decrease in mature sperms and histopathology confirmed the findings. The oxidative state was, however, comparable to control group. This study is the first to show that intracremasteric injections of Botox® induce adverse testicular effects evidenced by inhibited spermatogenesis and initiation of histopathological changes. In conclusion, decreased fertility may be a serious problem Botox® injections could cause. - Highlights: • Botox® injections are the trend nowadays, for both medical and non-medical uses. • They were recently suggested for cryptorchidism and testicular spasms. • This study outlines possible testicular adverse effects of these injections. • Botox® affected normal testicular function and physiology. • Infertility is a serious problem that Botox® injections could cause

  5. A Rare Cause of Testicular Metastasis: Upper Tract Urothelial Carcinoma

    OpenAIRE

    Manav, Alper Nesip; Kazan, Ercan; Ertek, Mehmet ?irin; Amasyal?, Ak?n Soner; Çulhac?, Nil; Erol, Haluk

    2014-01-01

    Metastatic testicular cancers are rare. Primary tumor sources are prostate, lung, and gastrointestinal tract for metastatic testicular cancers. Metastasis of urothelial carcinoma (UC) to the testis is extremely rare. Two-thirds of upper tract urothelial carcinoma (UTUC) is of invasive stage at diagnosis and metastatic sites are the pelvic lymph nodes, liver, lung, and bone. We report a rare case of metastatic UTUC to the testis which has not been reported before, except one case in the litera...

  6. Testicular function following the treatment of Hodgkin's disease in childhood.

    OpenAIRE

    Shafford, E. A.; Kingston, J. E.; Malpas, J. S.; Plowman, P N; Pritchard, J.; Savage, M.O.; Eden, O.B.

    1993-01-01

    Testicular function was studied in 40 males treated in childhood for Hodgkin's disease at St Bartholomew's Hospital, and the Hospital for Sick Children, London, between 1971-1985. All patients were 16 years or over at evaluation, and off treatment more than 6 years. Basal FSH, LH and testosterone levels were measured. Testicular size was measured using a Prader orchidometer, and all patients were offered a seminal analysis. Twenty-eight patients were treated with chemotherapy, usually ChlVPP....

  7. Effects of radiation therapy and chemotherapy on testicular function

    International Nuclear Information System (INIS)

    Chemotherapy and radiation therapy are commonly used alone or in combination in the curative management of many malignancies in adolescent and adult males. Over the last 15-20 years, the striking success in the treatment of some common cancers in reproductive males has led to increasing concern for damage to normal tissues, such as the testes, resulting from curative cancer treatment. Indeed, a major future goal for cancer treatment will be to improve on the complication-free cure rate. Inherent in achieving this goal is to understand the pathophysiology and clinical expression of testicular injury. Both chemotherapy and radiation therapy result in germ cell depletion with the development of oligo- to azoospermia and testicular atrophy. The type of drug (particularly the alkylating agents), duration of treatment, intensity of treatment, and drug combination are major variables in determining the extent and duration of testicular injury. Testicular injury with chemotherapy also appears to vary with the age of the patient at the time of treatment. Newer drug combinations are now being used which appear to have curative potential in tumors such as Hodgkin's disease and germ cell testicular cancer with less potential for testicular injury. The most accurate and complete information on radiation injury to the testes is derived from two studies of normal volunteers who received graded single doses directly to the testes. A clear dose-response relationship of clinical and histological testicular damage was found with gradual recovery occurring following doses of up to 600 cGy. While these two studies provide an important clinical data base, radiation therapy used in treating cancers involves multiple daily treatments, usually 25-35 delivered over several weeks. Additionally, direct testicular irradiation is seldom used clinically. 37 references

  8. Phthalate-induced testicular dysgenesis syndrome: Leydig cell influence

    OpenAIRE

    Hu, Guo-Xin; Lian, Qing-Quan; Ge, Ren-Shan; Hardy, Dianne O.; Li, Xiao-Kun

    2009-01-01

    Phthalates, the most abundantly produced plasticizers, leach out from polyvinyl chloride plastics and disrupt androgen action. Male rats that are exposed to phthalates in utero develop symptoms characteristic of the human condition referred to as testicular dysgenesis syndrome (TDS). Environmental influences have been suspected to contribute to the increasing incidence of TDS in humans (i.e. cryptorchidism and hypospadias in newborn boys and testicular cancer and reduced sperm quality in adul...

  9. Varicocele Repair Improves Testicular Histology in Men with Nonobstructive Azoospermia

    OpenAIRE

    Murat Ustuner; Hasan Yilmaz; Ufuk Yavuz; Seyfettin Ciftci; Ali Saribacak; Bahri Serkan Aynur; Hikmet Yasar; Mustafa Melih Culha

    2015-01-01

    Objective. To determine the histopathological differences after varicocele repair in testicular tissue in males with nonobstructive azoospermia. Methods. Between 2009 and 2014, 45 men with complete azoospermia and palpable varicocele, presenting with primary infertility of at least 1 year, undergoing varicocele repair at our institution were selected for the study. A standard systematic testicular 6-core Tru-Cut biopsy was performed during varicocele repair. Other biopsies were obtained from ...

  10. Neoplasias associadas ao carcinoma epidermóide do esôfago Esophageal epidermoid cancer associated neoplasms

    Directory of Open Access Journals (Sweden)

    C.C. Schirmer

    1997-12-01

    Full Text Available INTRODUÇÃO. O carcinoma epidermóide de esôfago (CEE tem uma importante associação com neoplasias do trato aerodigestivo e, provavelmente, compartilham dos mesmos fatores de risco. Além destes, outras neoplasias podem estar associadas com o carcinoma de esôfago. OBJETIVO. Analisar, retrospectivamente, pacientes com carcinoma epidermóide do esôfago tratados pelo Grupo de Cirurgia do Esôfago, Estômago e Intestino Delgado (GCEEID do Hospital de Clínicas de Porto Alegre (HCPA, no período de janeiro/88 a junho/95, os quais tinham neoplasias associadas ao CEE. PACIENTES E MÉTODOS. Dentre os 261 pacientes estudados, 19 (7,28% tinham neoplasia associada ao CEE. Dez pacientes apresentaram tumores sincrônicos e 9, metacrônicos. O sexo predominante foi o masculino, com 17 casos. A média de idade ficou em 62,52 anos no momento do diagnóstico da neoplasia esofágica. RESULTADOS. Os tumores aerodigestivos, na sua totalidade carcinomas escamosos, representaram o tipo histológico predominante da neoplasia associada em 68,42% dos casos. O sítio mais freqüente da neoplasia aerodigestiva associada foi a árvore respiratória (53,8%, seguido da cavidade oral e orofaringe (23% e laringe (23%. Dos 19 pacientes, 12 eram tabagistas e nove ingeriam bebidas alcoólicas regularmente. Para o tratamento do CEE, optou-se por cirurgia em seis pacientes. A neoplasia associada foi tratada com cirurgia radical em 11 pacientes e radioterapia em cinco. Surpreendentemente, foram diagnosticados quatro casos (21% de adenocarcinomas gástricos associados ao CEE, tratados com cirurgia radical em três pacientes. CONCLUSÃO. Os autores ressaltam a importância do estadiamento criterioso dos pacientes com CEE devido a associação significativa com outras neoplasias, principalmente com tumores aerodigestivos. Alertam para o seguimento desses pacientes e discutem a possibilidade de fatores de risco comuns: fumo e álcool. Nesta casuística, encontrou-se associação importante com neoplasias gástricas.INTRODUCTION. The esophageal epidermoid cancer has an important association with aerodigestive tract neoplasms and possibly share the same risk factors. Furthermore, other neoplasms can be associated with esophagus cancer. OBJECTIVE. To analyze retrospectively the patients with esophageal epidermoid cancer (EEC and associated neoplasms, treated by the Esophagus Stomach and Small Intestine Group of Surgery at Hospital de Clinicas de Porto Alegre from January 1988 to June 1995. PATIENTS AND METHODS. Nineteen (7.28% of the 261 studied patients had associated neoplasms to the EEC. Ten patients presented synchronic tumours and 9 metachronic ones. The predominant sex was the masculine with 17 cases. The mean age was 62.52 years in the moment of the esophageal cancer diagnostic. RESULTS. The aerodigestive tumours, squamous carcinomas in totality, represented the predominant associated neoplasm histological type in 68.42% of the cases. The most frequent associated aerodigestive tumours site was the respiratory tract (53.8%, followed by the oral cavity and oropharynx (23% and larynx (23%. In our sample, twelve patients were smokers and 9 were alcohol abusers. In relation to the EEC treatment, surgery was performed in 6 patients. The associated neoplasm was treated with radical surgery in 11 patients and radiotherapy in 5. Surprisingly 4 cases (21% of gastric adenocarcinoma associated to the EEC were diagnosed, treated with radical surgery in 3 patients. CONCLUSION. The authors call attention to the importance of a criterial staging as well as the follow up in patients with EEC owing to the significant association with others neoplasms, principally with aerodigestive tumours, and discuss the common risk factors possibility: tobacco and alcohol use. Important association with gastric neoplasms were found in this casuistry.

  11. Neoplasias associadas ao carcinoma epidermóide do esôfago / Esophageal epidermoid cancer associated neoplasms

    Scientific Electronic Library Online (English)

    C.C., Schirmer; R., Gurski; M.A.A., Castro; G.S.P., Madruga; F.L., Pedroso; C.D.P., Kruel; L., Brentano.

    1997-12-01

    Full Text Available INTRODUÇÃO. O carcinoma epidermóide de esôfago (CEE) tem uma importante associação com neoplasias do trato aerodigestivo e, provavelmente, compartilham dos mesmos fatores de risco. Além destes, outras neoplasias podem estar associadas com o carcinoma de esôfago. OBJETIVO. Analisar, retrospectivament [...] e, pacientes com carcinoma epidermóide do esôfago tratados pelo Grupo de Cirurgia do Esôfago, Estômago e Intestino Delgado (GCEEID) do Hospital de Clínicas de Porto Alegre (HCPA), no período de janeiro/88 a junho/95, os quais tinham neoplasias associadas ao CEE. PACIENTES E MÉTODOS. Dentre os 261 pacientes estudados, 19 (7,28%) tinham neoplasia associada ao CEE. Dez pacientes apresentaram tumores sincrônicos e 9, metacrônicos. O sexo predominante foi o masculino, com 17 casos. A média de idade ficou em 62,52 anos no momento do diagnóstico da neoplasia esofágica. RESULTADOS. Os tumores aerodigestivos, na sua totalidade carcinomas escamosos, representaram o tipo histológico predominante da neoplasia associada em 68,42% dos casos. O sítio mais freqüente da neoplasia aerodigestiva associada foi a árvore respiratória (53,8%), seguido da cavidade oral e orofaringe (23%) e laringe (23%). Dos 19 pacientes, 12 eram tabagistas e nove ingeriam bebidas alcoólicas regularmente. Para o tratamento do CEE, optou-se por cirurgia em seis pacientes. A neoplasia associada foi tratada com cirurgia radical em 11 pacientes e radioterapia em cinco. Surpreendentemente, foram diagnosticados quatro casos (21%) de adenocarcinomas gástricos associados ao CEE, tratados com cirurgia radical em três pacientes. CONCLUSÃO. Os autores ressaltam a importância do estadiamento criterioso dos pacientes com CEE devido a associação significativa com outras neoplasias, principalmente com tumores aerodigestivos. Alertam para o seguimento desses pacientes e discutem a possibilidade de fatores de risco comuns: fumo e álcool. Nesta casuística, encontrou-se associação importante com neoplasias gástricas. Abstract in english INTRODUCTION. The esophageal epidermoid cancer has an important association with aerodigestive tract neoplasms and possibly share the same risk factors. Furthermore, other neoplasms can be associated with esophagus cancer. OBJECTIVE. To analyze retrospectively the patients with esophageal epidermoid [...] cancer (EEC) and associated neoplasms, treated by the Esophagus Stomach and Small Intestine Group of Surgery at Hospital de Clinicas de Porto Alegre from January 1988 to June 1995. PATIENTS AND METHODS. Nineteen (7.28%) of the 261 studied patients had associated neoplasms to the EEC. Ten patients presented synchronic tumours and 9 metachronic ones. The predominant sex was the masculine with 17 cases. The mean age was 62.52 years in the moment of the esophageal cancer diagnostic. RESULTS. The aerodigestive tumours, squamous carcinomas in totality, represented the predominant associated neoplasm histological type in 68.42% of the cases. The most frequent associated aerodigestive tumours site was the respiratory tract (53.8%), followed by the oral cavity and oropharynx (23%) and larynx (23%). In our sample, twelve patients were smokers and 9 were alcohol abusers. In relation to the EEC treatment, surgery was performed in 6 patients. The associated neoplasm was treated with radical surgery in 11 patients and radiotherapy in 5. Surprisingly 4 cases (21%) of gastric adenocarcinoma associated to the EEC were diagnosed, treated with radical surgery in 3 patients. CONCLUSION. The authors call attention to the importance of a criterial staging as well as the follow up in patients with EEC owing to the significant association with others neoplasms, principally with aerodigestive tumours, and discuss the common risk factors possibility: tobacco and alcohol use. Important association with gastric neoplasms were found in this casuistry.

  12. Epidermoid carcinoma of the anal canal. A series of 276 cases

    Energy Technology Data Exchange (ETDEWEB)

    Papillon, J.; Montbarbon, J.F.

    1987-05-01

    During the past ten years, substantial progress has been made in the knowledge of the natural history of epidermoid carcinoma of the anal canal and of the response of the disease to radiotherapy alone or combined with chemotherapy. At the present time, the main problem in the management of this tumor concerns identification of the best modalities to achieve local control and preservation of anal function. From a series of 276 cases, followed for more than three years, the necessity for a careful pretreatment evaluation was stressed. This included a systematic search for pelvic metastatic lymph nodes by palpation and CT scan. All patients were treated initially by irradiation except those who underwent groin dissection for inguinal node metastasis or colostomy for complete anal obstruction. Three groups of patients have been identified: unresectable or disseminated tumors (33 cases), resectable tumors but not suitable for sphincter conservation (21 cases) treated by radiochemotherapy and delayed surgery, and resectable tumors suitable for sphincter conservation (222 cases) which were treated by a split-course regimen combining a short course of carefully planned external beam irradiation (19 days) followed by an iridium 192 implant after a two-month rest. In this group, which represents 80 percent of the whole series, 80 percent of patients have had their cancer controlled and 90 percent of controlled patients have retained normal anal function. The use of chemotherapy during the first days of irradiation is advisable in all cases to reinforce the efficacy of treatment and increase the chance of anal preservation. Results of the split-course regimen, combining external beam and interstitial irradiation, demonstrate a clear superiority over external beam irradiation alone, especially for large infiltrating tumors, which represent the majority of cases.

  13. Intracranial epidermoid cysts: diffusion-weighted, FLAIR and conventional MR findings

    Energy Technology Data Exchange (ETDEWEB)

    Hakyemez, Bahattin [Department of Radiology, Burtom Radioimaging Center, Ataturk cad, Feraizcizade sok., NO:1, Osmangazi, Bursa (Turkey)]. E-mail: bahattinh@hotmail.com; Aksoy, Umit [Department of Radiology, Bursa State Hospital, Bursa (Turkey); Yildiz, Harun [Department of Radiology, Suleyman Demirel University Medical School, Isparta (Turkey); Ergin, Necdet [Department of Neurosurgery, Bursa State Hospital, Bursa (Turkey)

    2005-05-01

    Purpose: To compare diffusion-weighted echo-planar imaging (DW) with spin-echo (SE), and fluid-attenuated inversion recovery (FLAIR) sequences in the evaluation of epidermoid cysts (ECs), and to evaluate T2 shine-through effect. Materials and methods: Fifteen patients were imaged prospectively in two different 1.5 T magnetic resonance (MR) units with standard head coils with SE, FLAIR and DW echo planar imaging sequences. The qualitative and quantitative assessments were performed by two radiologists in consensus. Apparent diffusion coefficient (ADC) values were obtained from all ECs. Exponential DW images are obtained in 11 cases to eliminate T2 shine-through effects. The results are analyzed with variance analysis (ANOVA) and Bonferroni t method. Results: FLAIR sequence was superior to T1- and T2-weighted sequences in showing ECs. In 13 cases, the borders of the lesions could be delineated from the surrounding structures with only DW imaging where ECs were markedly hyperintense. The ADC values of ECs are significantly lower than CSF (P < 0.001), and significantly higher than deep white matter (P < 0.01). On exponential DW images, ECs had similar intensity with brain parenchyma showing that the real cause of the hyperintensity of the lesions on trace images is the enhanced T2 effect of the tissue. Conclusion: FLAIR sequence is superior to the conventional MR sequences in demonstrating the ECs and DW imaging is superior to other MR sequences in delineating the borders of the ECs. Exponential DW images had shown that the hyperintensity in the trace images are caused by increased T2 effect of the lesion rather than the decrease in ADC values.

  14. Epidermoid carcinoma of the anal canal. A series of 276 cases

    International Nuclear Information System (INIS)

    During the past ten years, substantial progress has been made in the knowledge of the natural history of epidermoid carcinoma of the anal canal and of the response of the disease to radiotherapy alone or combined with chemotherapy. At the present time, the main problem in the management of this tumor concerns identification of the best modalities to achieve local control and preservation of anal function. From a series of 276 cases, followed for more than three years, the necessity for a careful pretreatment evaluation was stressed. This included a systematic search for pelvic metastatic lymph nodes by palpation and CT scan. All patients were treated initially by irradiation except those who underwent groin dissection for inguinal node metastasis or colostomy for complete anal obstruction. Three groups of patients have been identified: unresectable or disseminated tumors (33 cases), resectable tumors but not suitable for sphincter conservation (21 cases) treated by radiochemotherapy and delayed surgery, and resectable tumors suitable for sphincter conservation (222 cases) which were treated by a split-course regimen combining a short course of carefully planned external beam irradiation (19 days) followed by an iridium 192 implant after a two-month rest. In this group, which represents 80 percent of the whole series, 80 percent of patients have had their cancer controlled and 90 percent of controlled patients have retained normal anal function. The use of chemotherapy during the first days of irradiation is advisable in all cases to reinforce the efficacy of treatment and increase the chance of anal preservation. Results of the split-course regimen, combining external beam and interstitial irradiation, demonstrate a clear superiority over external beam irradiation alone, especially for large infiltrating tumors, which represent the majority of cases

  15. Testicular atrophy secondary to a large long standing incarcerated inguinal hernia

    Directory of Open Access Journals (Sweden)

    Nikolaos S Salemis

    2011-09-01

    Full Text Available Testicular atrophy is a rare but distressing complication of inguinal hernia repair. Apart from the postsurgical etiology, ischemic orchitis and subsequent testicular atrophy may occur secondary to compression of the testicular vessels by chronically incarcerated hernias. We present a rare case of testicular atrophy secondary to a large long standing incarcerated inguinal hernia of 2-decade duration in a 79-year-old man. Testicular atrophy should be always considered in long standing incarcerated inguinal hernias and patients should be adequately informed of this possibility during the preoperative work-up. Preoperative scrotal ultrasonography can be used to determine testicular status in this specific group of patients.

  16. Ecotoxicology and Testicular Damage (Environmental Chemical Pollution): A Review Ecotoxicología y Daño Testicular. (Contaminación Química Ambiental): Revisión

    OpenAIRE

    Eduardo Bustos-Obregón; Ricardo Hartley B

    2008-01-01

    This review briefly considers the testicular damage elicited by environmental chemical pollution. It includes a short comment on environmental toxicology as an introduction to environmental chemical pollution, highlighting the importance of this current field of study and its impact on male reproductive health. Furthermore an experimental animal model addressing the effect of organophosphorated agropesticides as a testicular toxicant is presented. Moreover two relevant chemical contaminants a...

  17. Manejo multidisciplinario en la recidiva de carcinoma epidermoide de conducto auditivo externo. Presentación de un caso / Multidisciplinary handling of epidermoid carcinoma in the external auditory canal. Presentation of a case

    Scientific Electronic Library Online (English)

    Misleidy, Nápoles Morales; Orlando, Cruz García; Juan Carlos, Alfonso Coto; Pedro Pablo, Morales; Carlos F, Calderón Marín; Eduardo, Larrinaga Cortinas; Jorge Juan, Marinillo Guerrero; Betty, Santodomingo Reyna.

    2011-06-01

    Full Text Available Se presenta un paciente de 42 años con el diagnóstico de un carcinoma epidermoide bien diferenciado de conducto auditivo externo (CAE), diagnosticado en junio de 2008. El mismo recibió radioterapia como tratamiento con intención curativa a dosis radical 66 Gy. En enero de 2010, comenzó con aumento d [...] e volumen exagerado del conducto auditivo externo, discutiéndose en los servicios de Neurocirugía, Radioterapia y Cirugía Reconstructiva del Instituto Nacional de Oncología y Radiobiología. Al paciente se le realiza la exéresis total del tumor, una radioterapia intraoperatoria fraccionada con electrones (EIORT) y reconstrucción local con colgajo músculo cutáneo del pectoral mayor. El tratamiento resultó ser tolerado por el paciente aumentándole su expectativa y calidad de vida. Abstract in english A 42 year-old patient is presented with the diagnostic of an Epidermoid Carcinoma of the external auditory canal on June 2008. He had got a radical radiotherapy as treatment with a completely response but in January 2010 he return with the tumour in the same place. It was the reason to discuss this [...] patient in different department as Neurosurgery, Radiotherapy and Reconstructive Surgery. This patient received a total remove of the tumour, Intraoperative Radiotherapy with electron (EIORT) and a local reconstruction with mayor Pectoral Muscle. As Result the treatments were bear by the patient increasing his expectative and quality life.

  18. Tratamiento quirúrgico conservador del quiste dentígero en pacientes pediátricos atendidos en el postgrado de cirugía bucal facultad de odontología de la UCV: Seguimiento a largo plazo

    Scientific Electronic Library Online (English)

    Sol C, Del Valle; José A, Cedeño; Raúl, García-Arocha; César, Guerrero.

    2007-09-01

    Full Text Available RESUMEN De acuerdo a numerosos autores el tratamiento para el quiste dentígero ha sido la eliminación total del quiste incluyendo el diente involucrado aunque si la lesión se presenta en pacientes jóvenes que están en período de erupción dentaria y las características clínicas y radiográficas sugier [...] en la presencia de un quiste dentígero, existe una alternativa de tratamiento la cual es la de mantener el diente permanente no erupcionado y enuclear completamente la lesión, siempre que se obtenga el diagnóstico definitivo histopatológico confirmatorio de quiste dentígero. Se realizó un estudio clínico en 12 pacientes de 7 a 16 años de edad con un promedio de 9,4 años, quienes fueron tratados en el Postgrado de Cirugía Bucal de la Facultad de Odontología de la Universidad Central de Venezuela (UCV). Todos los pacientes tenían las características clínicas y radiográficas similares a las del quiste dentígero, se encontraron 5 mujeres y 7 hombres, los cuales fueron sometidos a biopsia excisional, donde se les eliminó la lesión por completo, dejándoles el diente permanente no erupcionado. Las lesiones eran en la mandíbula y las imágenes radiolúcidas eran bien delimitadas al cuello dentario y menores a 2,5 cms. de diámetro. Los pacientes con quiste dentígero asociado a un tercer molar fueron excluídos del estudio. El estudio histopatológico fue confirmatorio de quiste dentígero para cada paciente y a cada uno se les realizó un seguimiento clínico y radiográfico periódico desde 2 meses hasta 7 años, con un intervalo aproximado de cada 6 meses. (1999-2006). No se encontraron imágenes radiolúcidas en ninguna de las radiografías post-quirúrgicas. Todos mostraron nueva formación ósea alrededor del diente involucrado y erupción completa de la dentición permanente. Tres(3) pacientes fueron seguidos por 7 años, cuatro(4) por 5 años, dos(2) por 3 años con 9 meses y tres(3) por 2 años y 6 meses. A dos(2) de los pacientes se les realizó tratamiento ortodóncico para corregir su maloclusión. Preservar el diente involucrado en un Quiste Dentígero al enuclear totalmente la lesión es una alternativa de procedimiento quirúrgico  con resultados clínicos y radiográficos predecibles y estables. Este tratamiento puede ser usado como un manejo quirúrgico conservador que permite la erupción normal de la dentición permanente. Éste estudio enfatiza la importancia del manejo multidisciplinario en equipo (Cirujano Bucal, Patólogo Bucal, Ortodoncista y Odontopediatra) y el control radiográfico postquirúrgico contínuo de los pacientes para asegurarnos de que no ha habido recidiva o la aparición de alguna nueva patología asociada Abstract in english ABSTRACT According to most authors the common treatment for the dentigerous cyst has been total elimination of the cyst including the tooth involved; however if the lesion is present in young patients during the eruption period, and the radiographic and clinical features are suggesting of dentigerou [...] s cyst, an alternative treatment is the maintenance of the permanent tooth and enucleation of the lesion alone, stating that ameloblastomatous changes or other odontogenic lesions have been ruled out after histopathological analysis, and a diagnosis of dentigerous cyst is confirmed. This study was conducted on 12 patients with an age range of 6 to 16 years with a mean age of 9.4 years that were treated at the Oral Surgery Postgraduate Department, Dental School, Central University of Venezuela. There were 5 females and 7 males. All lesions were mandibular and all of them were unilocular and well-defined radiolucencies measuring less than 2,5 cms in greatest diameter. All cases involved the coronal portion with cervical attachment of an unerupted permanent tooth. Third molars were excluded. Patients underwent surgery (excisional biopsy) of the cyst with preservation of the involved tooth. Histologic diagnosis of dentigerous cyst was confirmed in each case. Clinical and radiographic follow-up was performed at 6 months

  19. Duplicación del tubo digestivo manifestada como quiste lingual: Caso clínico y revisión de la literatura / Enteric duplication presented as lingual cyst: Case report and literature review

    Scientific Electronic Library Online (English)

    José Guillermo, Milán-Montenegro; Yolanda, Jaramillo-Rodríguez; Jesús, Nares-Cisneros; Jaime, Guerrero-Sepúlveda.

    2014-06-01

    Full Text Available Introducción: Los quistes de duplicación intestinal son anormalidades poco frecuentes que se presentan principalmente en el período perinatal, y pueden causar problemas respiratorios y para la alimentación. Los quistes sublinguales de duplicación intestinal pueden presentar solo epitelio del aparato [...] digestivo, del respiratorio o de ambos. En los dos últimos casos se denominan coristomas. Caso clínico: Se describe un caso de un paciente de 10 meses de edad que presentó una masa quística sublingual desde el nacimiento. Se realizó la resección total con abordaje transoral y la reconstrucción de la lengua en planos. La pieza quirúrgica resultó una estructura quística de contenido mucoide, de 23 × 17 × 11 mm y color marrón. El revestimiento del quiste estaba formado por mucosa gástrica, con epitelio foveolar y glándulas formadas por células parietales y principales. Conclusiones: El quiste de duplicación intestinal es una entidad extremadamente rara. El abordaje quirúrgico es eficaz y curativo con mínima morbilidad y mortalidad, sin recurrencia en su seguimiento. Abstract in english Background: Intestinal duplication cysts are rare abnormalities that occur primarily during the perinatal period and may cause problems for feeding and/or breathing. Sublingual intestinal duplication cysts can present either gastrointestinal epithelium or respiratory or both; the latter two cases ar [...] e called choristomas. Case report: We describe a 10-month-old infant who presented a sublingual cystic mass at birth. Total successful transoral resection and reconstruction of the tongue was performed in planes. The surgical specimen was a brown cystic structure of mucoid content with dimensions of 23 × 17 × 11 mm. The cyst lining consists of gastric mucosa with foveolar epithelium and glands composed of parietal and chief cells. Conclusions: The intestinal duplication cyst is an extremely rare entity. The surgical approach is effective and curative with minimal morbidity and mortality and without recurrence in follow-up.

  20. VARIACIONES DEL FUNCIONAMIENTO TESTICULAR Octopus mimus ADULTOS TESTICULAR FUNCTION VARIATIONS IN ADULT Octopus mimus

    Directory of Open Access Journals (Sweden)

    Alberto Olivares Paz

    2003-01-01

    Full Text Available Octopus mimus macho madura precozmente. En general, sobre 200 g son maduros y permanecen en dicha condición hasta la muerte. En consideración a que no hay antecedentes de la fisiología testicular de los machos adultos, fueron estudiadas la función gamética mediante análisis histológico de los túbulos seminíferos y la función endocrina, cuantificando en el testículo, progesterona y testosterona, en conjunto con el crecimiento y funcionalidad de los órganos blancos del andrógeno. Se detectaron tres categorías de machos adultos: maduros jóvenes, de madurez máxima y en regresión. Los animales en regresión producen menor cantidad de ambas hormonas y muestran regresión de la función espermatogénica. La declinación de ambas funciones del testículo indica el estado de envejecimiento de Octopus mimus. Por el contrario, los que están en máxima madurez tienen la mayor capacidad espermatogénica y androgénica, en conjunto con el mejor funcionamiento de las glándulas reproductivas anexas, cualidades que podrían ser consideradas en las normativas de manejo y futuras actividades de cultivo de la especieMale Octopus mimus attains precocious maturity. In general, they are mature when their weight is 200 g or more and remain so until death. Since testicular physiology in adult males is not known, spermatogenesis was analyzed by histological observation of seminiferous tubules and endocrine function by quantification of testicular concentration of progesterone and testosterone together with growth and functionality of the androgen target organs. Three classes of adult males were identified : young mature, maximal maturity and regression. Regressed animals produce less of both hormones tested and show spermatogenic involution. These two traits denote ageing in O. mimus. On the contrary maximal maturity shows high spermatogenic and steroidogenic function and of the glands in the reproductive male tract. These characteristics should be considered for adequate commercial exploitation of this species

  1. VARIACIONES DEL FUNCIONAMIENTO TESTICULAR Octopus mimus ADULTOS / TESTICULAR FUNCTION VARIATIONS IN ADULT Octopus mimus

    Scientific Electronic Library Online (English)

    Alberto, Olivares Paz; Eduardo, Bustos-Obregón; Vivian, Castillo Alvarez; Oscar, Zúñiga Romero.

    Full Text Available Octopus mimus macho madura precozmente. En general, sobre 200 g son maduros y permanecen en dicha condición hasta la muerte. En consideración a que no hay antecedentes de la fisiología testicular de los machos adultos, fueron estudiadas la función gamética mediante análisis histológico de los túbulo [...] s seminíferos y la función endocrina, cuantificando en el testículo, progesterona y testosterona, en conjunto con el crecimiento y funcionalidad de los órganos blancos del andrógeno. Se detectaron tres categorías de machos adultos: maduros jóvenes, de madurez máxima y en regresión. Los animales en regresión producen menor cantidad de ambas hormonas y muestran regresión de la función espermatogénica. La declinación de ambas funciones del testículo indica el estado de envejecimiento de Octopus mimus. Por el contrario, los que están en máxima madurez tienen la mayor capacidad espermatogénica y androgénica, en conjunto con el mejor funcionamiento de las glándulas reproductivas anexas, cualidades que podrían ser consideradas en las normativas de manejo y futuras actividades de cultivo de la especie Abstract in english Male Octopus mimus attains precocious maturity. In general, they are mature when their weight is 200 g or more and remain so until death. Since testicular physiology in adult males is not known, spermatogenesis was analyzed by histological observation of seminiferous tubules and endocrine function b [...] y quantification of testicular concentration of progesterone and testosterone together with growth and functionality of the androgen target organs. Three classes of adult males were identified : young mature, maximal maturity and regression. Regressed animals produce less of both hormones tested and show spermatogenic involution. These two traits denote ageing in O. mimus. On the contrary maximal maturity shows high spermatogenic and steroidogenic function and of the glands in the reproductive male tract. These characteristics should be considered for adequate commercial exploitation of this species

  2. Quiste dentígero: diagnóstico y resolución de un caso. Revisión de la literatura / Dentigerous cyst: diagnosis and resolution of a case. A review of the literature

    Scientific Electronic Library Online (English)

    J., Vázquez Diego; C., Gandini Pablo; E., Carvajal Eduardo.

    2008-12-01

    Full Text Available Se presenta un caso clínico de quiste dentígero asociado a un segundo premolar inferior derecho retenido. El paciente de 13 años de edad es de sexo masculino. Se utilizan las técnicas radiográficas extraoral lateral oblicua de rama y la intraoral del paralelo para poder localizar y diagnosticar pres [...] untivamente dicha patología. Posteriormente se realiza la intervención quirúrgica para realizar la extracción del diente retenido y la enucleación del quiste el que es enviado para realizar los estudios anatomopatológicos los que corroboran el diagnóstico presuntivo. Se decide hacer seguimiento del caso. Basado en lo expuesto se analiza al quiste dentígero según ubicación, sexo, edad y maxilar; habiendo realizado una revisión de la literatura. Abstract in english A clinical case of dentigerous cyst associated with an impacted lower right second premolar in a 13-year-old male patient, is reported. An extraoral oblique lateral technique of the ramus and a parallel intraoral technique were used to locate the cyst and to perform a presumptive diagnosis of the le [...] sion. A surgical procedure was then carried out to remove the impacted tooth and also to enucleate the cyst, which was sent to the laboratory for a histo-pathological study; this study confirmed our earlier presumptive diagnosis. Finally, we decided to follow-up the case. Based on our findings, dentigerous cyst is analyzed according to its location, sex and age of patients and most affected jaw, after reviewing the literature on this subject.

  3. Quiste de Gorlin asociado a Odontoma: reporte de un caso con su tratamiento quirúrgico Gorlin cyst associated with odontoma: Case report with surgical treatment

    Directory of Open Access Journals (Sweden)

    P. Villarroel Castro

    2005-12-01

    Full Text Available El quiste de Gorlin es un quiste odontogénico que puede presentarse en dos variedades, una quística rodeada por epitelio y de carácter benigno, y una neoplásica localmente agresiva. Se presenta elcaso de una mujer de 18 años con aumento de volumen facial indoloro en región infraorbitaria izquierda. Se realiza la exéresis total de la lesión. Con el estudio histopatológico se obtiene el diagnóstico definitivo de quiste de Gorlin asociado a odontoma. Luego de controles por 3 años, se observa el restablecimiento de la simetría facial, una adecuada regeneración ósea y de los tejidos adyacentes, sin signos de recidiva.Gorlin cyst is an odontogenic cyst that may appear as two types, one cystic and surrounded by epithelium of a benign nature, and the other a locally aggressive neoplasm. The case is presented of an 18-year-old female that had experienced an increase in facial volume in the left infraorbital area that was painless. Total exeresis of the lesion was carried out. The histopathologic study provided the definitive diagnosis of Gorlin cyst associated with odontoma. After a follow-up of three years, facial symmetry was reestablished, there was adequate regeneration of bone and of the adjacent tissue, and there were no signs of relapse.

  4. Quiste de Gorlin asociado a Odontoma: reporte de un caso con su tratamiento quirúrgico / Gorlin cyst associated with odontoma: Case report with surgical treatment

    Scientific Electronic Library Online (English)

    P., Villarroel Castro; R., Fariña Sirandoni; I., Espinoza Santander.

    2005-12-01

    Full Text Available El quiste de Gorlin es un quiste odontogénico que puede presentarse en dos variedades, una quística rodeada por epitelio y de carácter benigno, y una neoplásica localmente agresiva. Se presenta elcaso de una mujer de 18 años con aumento de volumen facial indoloro en región infraorbitaria izquierda. [...] Se realiza la exéresis total de la lesión. Con el estudio histopatológico se obtiene el diagnóstico definitivo de quiste de Gorlin asociado a odontoma. Luego de controles por 3 años, se observa el restablecimiento de la simetría facial, una adecuada regeneración ósea y de los tejidos adyacentes, sin signos de recidiva. Abstract in english Gorlin cyst is an odontogenic cyst that may appear as two types, one cystic and surrounded by epithelium of a benign nature, and the other a locally aggressive neoplasm. The case is presented of an 18-year-old female that had experienced an increase in facial volume in the left infraorbital area tha [...] t was painless. Total exeresis of the lesion was carried out. The histopathologic study provided the definitive diagnosis of Gorlin cyst associated with odontoma. After a follow-up of three years, facial symmetry was reestablished, there was adequate regeneration of bone and of the adjacent tissue, and there were no signs of relapse.

  5. Metástasis neurológicas secundarias a tumor testicular germinal / Neurological metastases secondary to germ cell testicular tumor

    Scientific Electronic Library Online (English)

    Roberto, Llarena Ibarguren; Igor, Azurmendi Arín; Jorge, García-Olaverri Rodríguez; Ivan, Olano Grasa; Emilio, Canton Aller; Carlos, Pertusa Peña.

    2008-10-01

    Full Text Available Objetivo: Las metástasis neurológicas secundarias a tumores urológicos suponen un 12% del total. Las derivadas de los tumores germinales testiculares en la época del cisplatino son excepcionales. Métodos: Presentamos un caso de tumor germinal mixto en un varón de 49 años tratado mediante quimioterap [...] ia sistémica desde 18 meses antes que presentó severa clínica neurológica central y periférica, que le condujo a la muerte por hemorragia cerebral masiva. Resultados: Se describen 3 tipos de presentación de las metástasis cerebrales en pacientes con cáncer testicular. El tipo 1 en el que se presentan sincrónicamente al tumor primario. El tipo 2 en el que se diagnostican tras un período de remisión luego del tratamiento citostático convencional. En el tipo 3 las metástasis se diagnostican durante el curso de la enfermedad y durante su tratamiento. Conclusiones: Salvo en caso de metástasis únicas encuadradas en el grupo 1 y 2 susceptibles de cirugía o radiocirugía, en el que cabe esperar respuesta, en el resto de lesiones secundarias a tumores germinales la evolución y el pronóstico son ominosos, con supervivencias escasas. Abstract in english Objective: Neurological metastases secondary to urological tumors account for 12% overall. The ones derived from germ cells testicular tumors are exceptional in the age of cisplatin. Methods: We report one case of mixed germ cell tumor in a 49-year-old male patient treated with systemic chemotherapy [...] during 18 months before presenting with severe central and peripheral neurological symptoms leading to death due to massive cerebral hemorrhage. Results: We describe three types of presentation of cerebral metastases in patients with testicular cancer. Type 1 present synchronically with the primary tumor. Type 2 are diagnosed after a period of remission after conventional cytostatic treatment. Type 3 metastases are diagnosed during the course of the disease and its treatment. Conclusions: Except unique metastases classified in groups I and 2, which are susceptible of surgery or radiosurgery, in which in response may be expected; the rest of lesions secondary to germ cell tumors have an ominous prognosis and outcomes, with short survivals.

  6. Development of a New and Efficient Laboratory Method for Processing Testicular Sperm

    OpenAIRE

    Hammitt, Diane G.; Ferrigni, Robert G.; Sattler, Chris A.; Rebert, Jessica A.; Singh, Anita P.

    2002-01-01

    Purpose: Testicular biopsy specimens contain large amounts of debris that makes sperm pick-up for ICSI more difficult than with epididymal aspirates. We sought to develop improved processing techniques for testicular sperm extraction (TESE).

  7. [Testicular tissue vitrification: evolution or revolution?].

    Science.gov (United States)

    Wyns, C; Abu-Ghannam, G; Poels, J

    2013-09-01

    Preservation of reproductive health is a major concern for patient long-term quality of life. While sperm freezing has proven to be effective to preserve fertility after puberty, cryopreservation of immature testicular tissue (ITT) is emerging as a promising approach for fertility preservation in young boys. Slow-freezing (SF) is the conventional method used to preserve ITT and has resulted in the birth of mice offspring. In humans, methods to preserve ITT are still at the research stage. Controlled SF using dimethyl sulfoxide showed preservation of proliferative spermatogonia after thawing in a xenotransplantation model used to evaluate the efficiency of freezing and thawing procedures. However, spermatogonial recovery was low and normal differentiation could not be achieved. Both freezing/thawing and the environment of the xenotransplantation model may be implicated. Indeed, with SF, ice crystal formation could damage tissue and cells. For this reason, vitrification, leading to solidification of a liquid without crystallization, may be a promising alternative. ITT vitrification has been investigated in different species and shown spermatogonial survival and differentiation to the round or elongated spermatids stage. Offspring were also recently obtained after vitrification and allotransplantation in avians, confirming the potential of vitrification for fertility preservation. In humans, vitrification appears to be as efficient as SF in terms of spermatogonial survival and initiation of differentiation after xenotransplantation. However, before validation of such fertility preservation methods, completion of normal spermatogenesis and the fertilization capacity of sperm retrieved from cryopreserved and transplanted tissue should be fully investigated. PMID:23958328

  8. Recurrent genomic rearrangements in primary testicular lymphoma.

    Science.gov (United States)

    Twa, David D W; Mottok, Anja; Chan, Fong Chun; Ben-Neriah, Susana; Woolcock, Bruce W; Tan, King L; Mungall, Andrew J; McDonald, Helen; Zhao, Yongjun; Lim, Raymond S; Nelson, Brad H; Milne, Katy; Shah, Sohrab P; Morin, Ryan D; Marra, Marco A; Scott, David W; Gascoyne, Randy D; Steidl, Christian

    2015-06-01

    Primary testicular diffuse large B cell lymphoma (PTL) is an aggressive malignancy that occurs in the immune-privileged anatomical site of the testis. We have previously shown that structural genomic rearrangements involving the MHC class II transactivator CIITA and programmed death ligands (PDLs) 1 and 2 are frequent across multiple B cell lymphoma entities. Specifically in PTL, we found rearrangements in the PDL locus by fluorescence in situ hybridization (FISH). However, breakpoint anatomy and rearrangement partners were undetermined, while CIITA rearrangements had not been reported previously in PTL. Here, we performed bacterial artificial chromosome capture sequencing on three archival, formalin-fixed, paraffin-embedded tissue biopsies, interrogating 20 known rearrangement hotspots in B cell lymphomas. We report novel CIITA, FOXP1 and PDL rearrangements involving IGHG4, FLJ45248, RFX3, SMARCA2 and SNX29. Moreover, we present immunohistochemistry data supporting the association between PDL rearrangements and increased protein expression. Finally, using FISH, we show that CIITA (8/82; 10%) and FOXP1 (5/74; 7%) rearrangements are recurrent in PTL. In summary, we describe rearrangement frequencies and novel rearrangement partners of the CIITA, FOXP1 and PDL loci at base-pair resolution in a rare, aggressive lymphoma. Our data suggest immune-checkpoint inhibitor therapy as a promising intervention for PTL patients harbouring PDL rearrangements. PMID:25712539

  9. Testicular tumors: oncologic imaging and diagnosis

    Energy Technology Data Exchange (ETDEWEB)

    Heiken, J.P.; Balfe, D.M.; McClennan, B.L.

    1984-02-01

    The extreme radiosensitivity of testicular seminomas plus recent advances in chemotherapy for nonseminomatous tumors and for advanced seminomas have made long term survival possible in the large majority of patients with testis cancer. Since choice of therapy is determined by tumor histology and extent of disease, accurate clinical staging is critical. Computed tomography (CT) of the abdomen and chest is the imaging procedure of choice for staging testis cancer. Clinical staging accuracy of 80 to 90% can be achieved using CT in combination with radio-immunoassays for ..beta..-HCG and AFP. Ultrasonography (US), while less sensitive and specific than CT for determining nodal status, may be useful in thin patients with sparse retroperitoneal fat. Lymphangiography should be reserved for Stage I patients in whom elective treatment of the retroperitoneum is not planned. Follow-up should include serial radioimmunoassays for serum AFP and ..beta..-HCG and periodic CT examinations of the abdomen and chest. In addition, nuclear magnetic resonance (NMR) imaging and radionuclide imaging following injection of radioactively labelled antibodies to AFP and ..beta..-HCG are new techniques which offer great promise for the future.

  10. Resultados de la Cirugía Laparoscópica en Quistes Hepáticos No Parasitarios / Results of Laparoscopic Surgery in Nonparasitic Hepatic Cysts

    Scientific Electronic Library Online (English)

    Carlos, Manterola.

    2013-09-01

    Full Text Available Los quistes hepáticos no hidatídicos (QHNH) se detectan de forma incidental, pueden ser únicos y múltiples. Desde que se describió el tratamiento laparoscópico de estos, se han reportado diversas series; existiendo por ende evidencia que avala la cirugía laparoscópica de estas lesiones. El objetivo [...] de este estudio, es reportar los resultados del tratamiento laparoscópico de QHNH en términos de morbilidad postoperatoria (MPO). Serie de casos. Se incluyeron pacientes intervenidos quirúrgicamente vía laparoscópica por QHNH en el Hospital Clínico de la Universidad Mayor entre enero de 2008 y diciembre de 2012. El estudio preoperatorio consistió en exámenes generales, determinación de ELISA-IgE e IgG para hidatidosis, ecotomografía abdominal o tomografía computarizada. En el período estudiado, se intervinieron 17 pacientes con QHNH, resecándose en ellos, un total de 39 quistes. El 76,5% de los casos eran de sexo femenino; y la mediana de edad de la serie fue de 56 años. La mediana del diámetro ecográfico de las lesiones fue de 7,5 cm. Se realizó quistectomía subtotal en todos ellos, sin utilización de drenaje. Se realizó epiploplastia en 4 pacientes. En el 82,4% de los casos se ejecutó de forma simultánea una colecistectomía por colelitiasis. La mediana del tiempo quirúrgico fue de 51 minutos. No fue necesario convertir a ningún paciente. La serie no registra MPO ni mortalidad. La mediana de estancia hospitalaria fue de 1 día. El estudio histopatológico confirmó "quiste de tipo biliar" en la totalidad de los casos. Con un seguimiento mínimo de 6 meses, no se ha evidenciado MPO tardía ni reaparición de las lesiones resecadas. El tratamiento aplicado a esta serie de casos de QHNH, se asocia a escasa estancia hospitalaria y buena evolución a corto y mediano plazo. Abstract in english Nonparasitic hepatic cysts (NPHC) can be detected incidentally, and may be single or multiple. Since described laparoscopic treatment of NPHC, several series have been reported, therefore there is enough evidence that support the role of laparoscopic surgery in the treatment of NPHC. The aim of this [...] study is to report the results of laparoscopic treatment of QHNH in terms of postoperative morbidity (POM). Case series. Patients operated laparoscopically by NPHC in the Universidad Mayor Clinical Hospital, Temuco, between January 2008 and December 2012 were included. The preoperative evaluation consisted of general exams, ELISA-IgE and IgG determination for hydatid disease, abdominal ultrasonography or abdominal CT scan. During the study period, 17 patients with NPHC were operated, resecting them a total of 39 cysts. 76.5% of patients were female, and the median age of the series was 56 years. The median sonographic diameter of the lesions was 7.5 cm. Subtotal cystectomy was performed in all of them, without using drainage. Epiploplasty was performed in 4 patients. In 82.4% of cases simultaneously cholecystectomy for cholelithiasis was performed. The median operative time was 51 minutes. Neither patient was converted. The series does not register MPO or mortality. The median hospital stay was 1 day. Histopathology confirmed the "biliary type cyst" in all cases. With a minimum follow up of 6 months, there is no evidence or late MPO or recurrence of the lesions resected. The treatment applied to this series of NPHC, is associated with short hospital stay and good outcome in the short and medium term.

  11. Quiste de conducto de Skene en niñas: A propósito de 2 casos clínicos / Skene duct cyst in female newborns: Case reports

    Scientific Electronic Library Online (English)

    Alberto, Miño Barrera; Jorge, Rodríguez Herrera.

    2014-10-01

    Full Text Available Introducción: El quiste del conducto de Skene, se describe dentro de los quistes parauretrales, siendo una rara anomalía congénita descrita en neonatos de sexo femenino, que se puede presentar en el transcurso de la vida. La incidencia varía de 1 cada 2.000-3.000 recién nacidos vivos femeninos. Obje [...] tivo: Dar a conocer las características y formas de presentación del quiste del conducto de Skene en distintas etapas del desarrollo del niño para su sospecha y diagnóstico oportuno. Casos clínicos: Se presenta una recién nacida con una lesión tumoral amarillenta, adyacente al meato uretral, no dolorosa, que drena espontáneamente y un segundo caso de una adolescente que consulto por leucorrea de un año de evolución, con una lesión parauretral de tres centímetros de diámetro entre labios menores, que requirió tratamiento quirúrgico y estudio de la masa parauretral. Conclusiones: Basado en la revisión de la literatura, concluimos que la frecuencia de los quistes de conducto de Skene es más alta que el número de casos informados. La extirpación, marsupialización, la punción y aspiración del quiste son todos métodos eficaces de tratamiento. El drenaje espontáneo también es una conducta apropiada en ciertos casos. Se sugiere utilizar la técnica menos agresiva acorde a cada caso. Abstract in english Introduction: The Skene duct cyst, classified as a paraurethral cyst, is a rare congenital abnormality in female neonates and it may manifest throughout the course of life. The incidence varies from 1 in 2000 to 3000 female births. Objective: To expose the characteristics and symptoms of a Skene duc [...] t cyst at different stages of child development in order to carry out a timely suspicion and diagnosis. Case report: The first case is a female newborn who presented a painless yellowish tumor adjacent to the urethral meatus, which drained spontaneously; the second case is a teenager who consulted due to leucorrhea for a year and a three-centimeter diameter paraurethral injury between the labia minora, which required surgical treatment and study of the paraurethral mass. Conclusions: Based on the literature review, we concluded that the frequency of Skene duct cyst is higher than the number of reported cases. Cyst removal, marsupialization, puncture and aspiration are all effective treatment methods. Spontaneous drainage is also appropriate in certain cases. We suggest the use of the least aggressive technique according to each case.

  12. Testicular changes observed in boars following experimental inoculation with pseudorabies (Aujeszky's) virus.

    OpenAIRE

    Hall, L. B.; Kluge, J P; Evans, L E; Clark, T L; Hill, H T

    1984-01-01

    Four boars were inoculated intranasally with pseudorabies virus to determine if microscopic testicular changes occurred as a result of infection. Testicular biopsies and semen samples were taken at two, four and six weeks postinoculation and the boars were castrated immediately after the last sample collection. Testicular samples and semen were cultured to determine if the virus was present. Pseudorabies virus was not isolated from the semen or testicular tissue. Virus was isolated from trige...

  13. Testicular cancer: management challenges in an African developing country

    Scientific Electronic Library Online (English)

    F O, Ugwumba; A E, Aghaji.

    2010-07-01

    Full Text Available BACKGROUND: Advances in oncology have greatly improved the prognosis of testicular cancer. In developing countries, however, the outcome is still poor. PATIENTS AND METHODS: Twenty-four patients managed for testicular cancer at two centres (University of Nigeria Teaching Hospital, Enugu, Nigeria, an [...] d JAMA Urological Clinic, Enugu) between April 1984 and March 2003 were prospectively studied. Histopathological data were obtained in all cases. RESULTS: Peak age incidence was 20 - 29 years. Testicular swelling was the principal complaint in 23 patients. The mean interval between onset of symptoms and presentation was 5.3 months. Two patients (8.3%) presented with stage 1 disease, 7 (29.2%) with stage 2, 7 (29.2%) with stage 3, and 8 (33.3%) with stage 4. Seventy-five per cent of tumours were right-sided, and 25% were left-sided. Treatment consisted of radical orchidectomy in all patients and cisplatin-based chemotherapy and radiotherapy in some patients. One patient with a tumour in an intra-abdominal testis underwent laparotomy. The most common histological types were seminoma and embryonal carcinoma. A fifth of the patients died, while half were lost to follow-up. The mean follow-up period was 9 months. CONCLUSION: Morbidity and mortality of testicular cancer is high in developing countries. Late presentation, poverty, paucity of resources and the high cost of newer imaging modalities and treatment are major challenges to management. Better health funding and education regarding testicular self-examination is essential.

  14. Diagnóstico en Torsión de Pedículo de Quiste Anexial en Ginecología / Diagnosis in torsion of adnexal cyst in gynecology

    Scientific Electronic Library Online (English)

    Freddy, Maita Q.; Erwin, Hochstatter Arduz; Oscar, Niño de Guzman Peña.

    Full Text Available Objetivos: Evaluar los signos clínicos, ecográficos y Doppler color en el diagnóstico de la torsión de pedículo. Métodos: Estudio observacional prospectivo de corte transversal, incluyó a 22 pacientes durante un período de tres años, que acudieron, con dolor abdominal agudo y presencia de quiste ane [...] xial. Las edades comprendidas fueron entre 22 y 58 años. Resultados: Cotejados con los hallazgos quirúrgicos y la evolución clínica: de 22 pacientes, 9 tenían torsión de pedículo; la tríada clásica mostró una sensibilidad de 55%, especificidad del 46%, valor predictivo positivo del 42%, valor predictivo negativo del 60%. El signo directo de torsión de pedículo mostró una sensibilidad de 78%, especificidad de 92%, valor predictivo positivo de 87%, valor predictivo negativo del 86%. El Doppler color mostró una sensibilidad de 100%, especificidad de 69%, valor predictivo positivo de 69%, valor predictivo negativo de 100%. El líquido libre abdominal mostró un resultado variable. Conclusiones: La sospecha clínica es el primer paso en el diagnóstico; el hallazgo del signo directo de torsión fue el de mayor valor diagnóstico; el hallazgo de señal Doppler color en la pared del quiste prácticamente, descartó la posibilidad de torsión. Abstract in english Objectives: To evaluate the clinical, ultrasonography signs and Doppler color in the diagnosis of the torsión of pedicle. Methods: Prospective observational study of cross-section included 22 patients over a period of three years, who attended with acute abdominal pain and presence of anexial cyst. [...] With an age range between 22 and 58 years. Results: 22 patients, 9 had torsión of pedicle; triad classic showed a 55% sensitivity, specificity 46%, positive predictive value 42%, negative predictive value 60%. The direct sign of torsión of pedicleshowed a sensitivity of 78%, specificity 92%, positive predictive value 87%,negative predictive value of 86%. The absence of Doppler signal colorshowed a sensitivity of 100%, specificity of 69%, positive predictive value 69%, negative predictive value of 100%. The abdominal free liquid showed a variable result. Conclusions: The clinical suspicion is the first passage in the diagnosis; the finding of the direct sign of torsión was the one of greater value diagnosis; the finding of color Doppler signal in the wall of the cyst practically, discarded any possibility of torsion.

  15. Neonatal outcome and congenital malformations in children born after ICSI with testicular or epididymal sperm

    DEFF Research Database (Denmark)

    Fedder, J; Loft, A; Parner, Erik Thorlund; Rasmussen, S; Pinborg, A

    2013-01-01

    Does neonatal outcome including congenital malformations in children born after ICSI with epididymal and testicular sperm [testicular sperm extraction (TESE)/percutaneous epididymal sperm aspiration (PESA)/testicular sperm aspiration (TESA) (TPT)] differ from neonatal outcome in children born after ICSI with ejaculated sperm, IVF and natural conception (NC)?

  16. P53 overexpression in epidermoid carcinoma of the head and neck

    Scientific Electronic Library Online (English)

    Angela Flavia, Logullo; Luiz Paulo, Kowalski; Sueli, Nonogaki; Roberto E. V., Miguel; Humberto, Torloni; Ricardo R., Brentani.

    1997-02-01

    Full Text Available A teoria de campo de cancerização em neoplasias de cabeça e pescoço (CP) reflete a complexa oncogênese que ocorre nesta região. Os mecanismos a nível molecular que controlam a proliferação celular em Carcinomas epidermóides (CEC) de vias aerodigestivas superiores ainda são pouco conhecidos. Mutações [...] no p53 são as alterações genéticas mais encontradas em CEC de CP e parecem contribuir ativamente em seu processo carcinogênico como gene supressor de tumor e a sua associação com tabaco. O objetivo deste trabalho é analisar a expressão da proteína p53 em carcinoma epidermóide de cabeça e pescoço por meio de reação imunohistoquimica e sua correlação com outros fatores prognósticos. O estudo inclui 63 casos consecutivos de CEC, não tratados previamente. Espécimes de tumor e de mucosa normal adjacente foram colhidos durante o ato cirúrgico e submetidos a reação imunohistoquímica para avaliação da expressão do anticorpo anti-proteína p53 (M7001 DAKO AVS, Denmark Inc.) Não houve significância entre os dados anatomo-clínicos e demográficos, presença de metastases linfonodais e a expressão de p53 no tumor ou na mucosa adjacente normal. A localização do tumor na laringe apresentou correlação estatistica significativa com a expressão da p53 . A graduação histológica, separada em graus I e ll, e III e IV apresentou correlação com a expressão de p53 significante ( p=0,025). Conclusões: 1-No material estudado proveniente de 63 casos de CEC de cabeça e pescoço encontramos 48% de superexpressão de p53 imunohistoquimicamente detectável, índice compatível com os demais relatados na literatura; 2-Não encontramos relação entre os dados demográficos do paciente e a expressão de p53 no tumor e na mucosa normal adjacente; 3- O achado de superexpressão de p53 mais freqüente em Material de CEC de laringe foi estatisticamente significativo. 4-A presença de 12 casos com superexpressão de p53 na mucosa normal adjacente e com tumor p53 negativo esta de acordo com a teoria de cancerização de campo. O seguimento desta série por maior tempo possibilitará uma melhor análise destes valores. Abstract in english The theory of field cancerization in tumors of the head and neck reflects the complex oncogenesis that occurs in this region. The mechanisms that control cell proliferation at the molecular level in epidermoid carcinomas (ECs) of the upper aerodigestive tract are still unclear. Mutations in p53 are [...] the genetic alterations most often detected in ECs of the head and neck and seem to contribute actively to the carcinogenic process triggered by p53 as a tumor-suppressor gene and to its association with tobacco. The objective of the present study was to investigate the expression of p53 protein in epidermoid head and neck carcinomas by immunohistochemistry and its immunohistochemical correlation with other prognostic factors. The study was conducted on 63 consecutive ECs cases not submitted to previous treatment. Specimens of the tumor and of the normal adjacent mucosa were collected during surgery and submitted to immunohistochemical reaction for the determination of the expression of anti-protein p53 antibody (M7001 DAKO A/S, Denmark). Anatomo-clinical and demographic data were not significantly correlated with the presence of lymph node metastases or p53 expression in the tumor or in the adjacent normal mucosa. Tumor localization in the larynx was significantly correlated with p53 expression. Histological grading as grades I, II, Ill and IV was correlated with significant p53 expression (p = 0.025). Conclusions: 1) in the studied material obtained from 63 cases of head and neck ECs, we detected a 48 percent rate of immunohistochemically detectable p53 overexpression; 2) we did not detect a relationship between demographic patient data and p53 expression in the tumor or in the normal adjacent mucosa; 3) p53 overexpression was significantly more frequent in ECs material from the larynx; and 4) The presence of 12 cases with p53 overexpression in t

  17. Metástases de coróide de origem testicular: relato de caso / Choroid metastasis of testicular primary site: case report

    Scientific Electronic Library Online (English)

    Marcos Rogério Mistro, Piccinin; João Augusto de, Almeida Jr.; Ricardo Dutra, Aydos; Daniel Cruz, Nogueira; Reinaldo Ferreira da, Silva.

    2006-12-01

    Full Text Available Descrição do caso de um paciente masculino de 22 anos de idade, cor parda, com decréscimo da acuidade visual em olho esquerdo e com diagnóstico de tumor testicular e metástases para pulmão e rim. Avaliação da evolução da lesão coroideana compatível com metástase ocular de tumor testicular por meio d [...] e exame oftalmológico e ecográfico. Houve resolução da lesão intra-ocular juntamente com melhora radiológica pulmonar após quimioterapia durante aproximadamente 4 meses de acompanhamento. Apesar da remissão da lesão ocular, o paciente faleceu por complicações decorrentes de metástase cerebral. Abordada na literatura como rara, não foi encontrado qualquer relato de caso sobre a metástase de coróide com sítio testicular, sendo esta, talvez, sua primeira descrição. Abstract in english Description of a male patient case, 22 years old, presenting visual acuity decrease in the left eye associated with the diagnosis of metastatic testicular tumor to lung and kidney. Evaluation of the evolution of a choroid lesion compatible with ocular metastasis of testis tumor through ophthalmologi [...] c and echographic examinations. There was resolution of the intraocular lesion together with lung radiologic improvement after chemotherapy during approximately 4 months of follow-up. In spite of the remission of the ocular lesion, the patient died due to complications of cerebral metastasis. Approached in the literature as rare, no report was found of a case of choroidal metastasis of a testicular site, this being, perhaps, its first description.

  18. Studies on the influence of radiation and chemotherapy on pituitary-testicular axis in patients with testicular tumor

    Energy Technology Data Exchange (ETDEWEB)

    Ogawa, Katsuaki (Yokohama City Univ. (Japan). Faculty of Medicine)

    1982-02-01

    Radiation and chemotherapy have been known as the highly effective treatment of patients with testicular tumor. To evaluate the influences of the therapies on pituitary-testicular axis, plasma FSH, LH and testosterone were determined by radioimmunoassay in 60 patients with testicular tumor before and after 1 to 102 months in the completion of radiation and chemotherapy. The results were summarized as follows: 1) In 10 out of 24 patients, plasma FSH and LH levels significantly increased within 20 months after 2,100 - 4,500 rad/3 - 6 weeks of radiation therapy. 2) In combination chromotherapy popularly used for testicular tumor, plasma FSH and LH in 8 of 22 patients markedly elevated within 20 months after the treatment. 3) The elevated gonadotropins returned to normal levels in approximately 50 months in patients received radiation or chemotherapy. 4) Plasma testosterone revealed normal levels in any therapeutic programs employed in the present study. 5) From the results of Gn-RH test, the pituitary gland seemed to have normal function. 6) Plasma testosterone showed incomplete response to hCG stimulation after 1 to 35 months of radiation or chemotherapy. Therefore, it was suggested that radiation and chemotherapy for the treatment of testicular tumor may impair not only seminiferous tubules but also Leydig cell for a couple of years.

  19. Endocrinology of Testicular Descent and Hormonal Therapy in Cryptorchidism

    Directory of Open Access Journals (Sweden)

    M Mollaiyan

    1998-05-01

    Full Text Available The mystery of testicular descent remains a challenge for urological research. In this article the impressive investigational output in recent years, especially the role of mullerian inhibitory substance and the genito-femoral nerve, are reviewed. It is currently suggested that hypogonadotropic hypogonadism plays a more central; role. How this interacts in the complex process of testicular descent remains to be investigated. Testicular biopsies in cryptorchidism demonstrate histologic depletion of germ cells and leydig cells in undescended testicle, as well as in the contralateral descended testis in many cases. European use LHRH and HCG for assisting scrotal positioning of "Almost" descended testes, while north American investigators use HCG, but not LHRH hormone, to reveal retractile testes.

  20. Leydig cell damage after testicular irradiation for lymphoblastic leukemia

    Energy Technology Data Exchange (ETDEWEB)

    Shalet, S.M.; Horner, A.; Ahmed, S.R.; Morris-Jones, P.H.

    1985-01-01

    The effect of testicular irradiation on Leydig cell function has been studied in a group of boys irradiated between 1 and 5 years earlier for a testicular relapse of acute lymphoblastic leukemia. Six of the seven boys irradiated during prepubertal life had an absent testosterone response to HCG stimulation. Two of the four boys irradiated during puberty had an appropriate basal testosterone level, but the testosterone response to HCG stimulation was subnormal in three of the four. Abnormalities in gonadotropin secretion consistent with testicular damage were noted in nine of the 11 boys. Evidence of severe Leydig cell damage was present irrespective of whether the boys were studied within 1 year or between 3 and 5 years after irradiation, suggesting that recovery is unlikely. Androgen replacement therapy has been started in four boys and will be required by the majority of the remainder to undergo normal pubertal development.

  1. Lonidamine affects testicular steroid hormones in immature mice

    International Nuclear Information System (INIS)

    The effects on the hypothalamus-pituitary-testicular axis of the well-known antispermatogenic drug lonidamine (LND) has not been elucidated so far. In the present study, the possible changes of the testicular steroid hormones were evaluated in immature mice for a better characterization of the LND adverse effects both in its use as antitumoral agent and male contraceptive. Male CD1 mice were orally treated on postnatal day 28 (PND28) with LND single doses (0 or 100 mg/kg b.w.) and euthanized every 24 h from PND29 to PND32, on PND35 and on PND42 (1 and 2 weeks after the administration, respectively). Severe testicular effects were evidenced in the LND treated groups, including: a) significant testis weight increase, 24 h and 48 h after dosing; b) sperm head counts decrease (more than 50% of the control) on PND29-32; c) damage of the tubule morphology primarily on the Sertoli cell structure and germ cell exfoliation. All these reproductive endpoints were recovered on PND42. At the same time, a significant impairment of the testicular steroid balance was observed in the treated mice, as evidenced by the decrease of testosterone (T) and androstenedione (ADIONE) and the increase of 17OH-progesterone (17OH-P4) on the first days after dosing, while the testicular content of 17?-estradiol (E2) was unchanged. The hormonal balance was not completely restored afterwards, as levels of T, ADIONE and 17OH-P4 tended to be higher in the treated mice than in the controls, on PND35 and PND42. These data showed for the first time that LND affects intratesticular steroids in experimental animals. However further data are needed both to elucidate the mechanism responsible for the impairment of these metabolic pathways and to understand if the androgens decrease observed after LND administration could be partially involved in the testicular damage

  2. Manejo multidisciplinario en la recidiva de carcinoma epidermoide de conducto auditivo externo. Presentación de un caso Multidisciplinary handling of epidermoid carcinoma in the external auditory canal. Presentation of a case

    Directory of Open Access Journals (Sweden)

    Misleidy Nápoles Morales

    2011-06-01

    Full Text Available Se presenta un paciente de 42 años con el diagnóstico de un carcinoma epidermoide bien diferenciado de conducto auditivo externo (CAE, diagnosticado en junio de 2008. El mismo recibió radioterapia como tratamiento con intención curativa a dosis radical 66 Gy. En enero de 2010, comenzó con aumento de volumen exagerado del conducto auditivo externo, discutiéndose en los servicios de Neurocirugía, Radioterapia y Cirugía Reconstructiva del Instituto Nacional de Oncología y Radiobiología. Al paciente se le realiza la exéresis total del tumor, una radioterapia intraoperatoria fraccionada con electrones (EIORT y reconstrucción local con colgajo músculo cutáneo del pectoral mayor. El tratamiento resultó ser tolerado por el paciente aumentándole su expectativa y calidad de vida.A 42 year-old patient is presented with the diagnostic of an Epidermoid Carcinoma of the external auditory canal on June 2008. He had got a radical radiotherapy as treatment with a completely response but in January 2010 he return with the tumour in the same place. It was the reason to discuss this patient in different department as Neurosurgery, Radiotherapy and Reconstructive Surgery. This patient received a total remove of the tumour, Intraoperative Radiotherapy with electron (EIORT and a local reconstruction with mayor Pectoral Muscle. As Result the treatments were bear by the patient increasing his expectative and quality life.

  3. Sexual dysfunctions in men treated for testicular cancer

    DEFF Research Database (Denmark)

    Rosendal, Susanne; Kristensen, Ellids; Giraldi, Annamaria G E

    2008-01-01

    Patients treated for testicular cancer have increased risk of ejaculatory, orgasmic and erectile dysfunction compared with healthy men. The underlying relations are unclear. This review describes sexual dysfunctions that are associated with various treatment modalities. One meta-analysis and 11...... original works were examined. About one third of the patients experience one or more sexual problems in relation to the treatment. Only retroperitoneal surgery can cause a specific sexual dysfunction, namely loss of ejaculation ability or ejaculatory functioning. Psychosexual causes are important for...... understanding sexual dysfunctions in patients with testicular cancer....

  4. Testicular Parameters and Morphological Characteristics of Testicular and Epididymal Spermatozoa of White Fulani Bulls in Nigeria Parámetros Testiculares y Características Morfológicas de los Espermatozoides Testicular y Epididimal de Toros Fulani Blancos en Nigeria

    Directory of Open Access Journals (Sweden)

    Matthew Olugbenga Oyeyemi

    2006-06-01

    Full Text Available Testicular parameters and morphological characteristics of testicular and epididymal spermatozoa of white Fulani bulls were study using twenty testicles. The objective was to study the normal testicular parameter and morphological changes during epididymal transit in the epididymis of white Fulani bulls. It was observed that there was reduction in the proportion of spermatozoa carrying the proximal cytoplasmic droplet (PCD along the epididymis as spermatozoa mature. There were more narrow head in the left (0.40 than the right epididymis (0.10. There was more bent normal tail (16.7 in the left epididymis than in right epididymis (13.0. The sperm cells having looped tails are higher in the left epididymis (caput, 4.90; corpus, 5.30; caudal 4.30 than the right epididymis (caput, 4.70; corpus, 3.20; caudal 5.10 despite the fact that the caudal epididymis in the right epididymis has a higher mean value. In this study the left testicle had more of the morphologically defective spermatozoa (12.96% than the right testicles (12.42%. The epididymal and testicular parameters were positively correlated (weight of epididymis, weight of estis and epididymis, length of epididymis, circumference of the testes and epididymis, (pSe estudiaron parámetros testiculares y características morfológicas de los espermatozoides testiculares y epididimarios en 20 testículos de toros Fulani blancos. El objetivo fue determinar parámetros testiculares normales y los cambios morfológicos de los espermatozoides durante su trayecto en el epidídimo. Se observó que hubo disminución de espermatozoides llevando droplet citoplasmático proximal (PCD en el epidídimo, durante la maduración espermática. Se presentaron más cabezas estrechas en el epidídimo izquierdo (0,40 que en el derecho (0,10. Hubo más espermatozoides con cola normal (16.7 en el epidídimo del lado izquierdo que en el lado derecho (13.0. Las células espermáticas tenían colas en loop en mayor cantidad en el epidídimo izquierdo (cabeza, 4.90; cuerpo, 5.30; cola 4.30 que en el lado derecho (cabeza, 4.70; cuerpo, 3.20; cola 5.10. Sin embargo, en la zona caudal del epidídimo derecho el valor promedio fue más alto. En este estudio, en el testículo izquierdo los espermatozoides presentaron más defectos morfológicos (12.96 que en el derecho (12.42. Entre los parámetros epididimarios y testiculares hubo correlación positiva (peso del epidídimo, peso de los testículos y epidídimos, longitud del epidídimo y circunferencias de los testículos y epidídimos p<0.05

  5. Simultaneous ipsilateral testicular seminoma with pelvic ectopy and hematovesicula seminalis

    Directory of Open Access Journals (Sweden)

    Hadži-?oki? Jovan

    2012-01-01

    Full Text Available We present a rare case of 24 years old male who was diagnosed with simultaneous testicular tumor with pelvic ectopy and ipsilateral hematovesicula seminalis. Hemospermia was the only presented symptom. Patient underwent surgery and removal of the testicular tumor and right vesiculectomy were performed.Histopathological analysis revealed seminoma of the right testis and dilated right vesicula seminalis filled with hemorrhagic fluid and sings of chronic inflammation. Postoperatively irradiation of the abdomen was performed using standard protocol. Ten years after surgery there was no signs of decease recurrence.

  6. Testicular Parameters and Morphological Characteristics of Testicular and Epididymal Spermatozoa of White Fulani Bulls in Nigeria / Parámetros Testiculares y Características Morfológicas de los Espermatozoides Testicular y Epididimal de Toros Fulani Blancos en Nigeria

    Scientific Electronic Library Online (English)

    Matthew Olugbenga, Oyeyemi; Temilade Babalola, Eunice.

    2006-06-01

    Full Text Available Se estudiaron parámetros testiculares y características morfológicas de los espermatozoides testiculares y epididimarios en 20 testículos de toros Fulani blancos. El objetivo fue determinar parámetros testiculares normales y los cambios morfológicos de los espermatozoides durante su trayecto en el e [...] pidídimo. Se observó que hubo disminución de espermatozoides llevando droplet citoplasmático proximal (PCD) en el epidídimo, durante la maduración espermática. Se presentaron más cabezas estrechas en el epidídimo izquierdo (0,40) que en el derecho (0,10). Hubo más espermatozoides con cola normal (16.7) en el epidídimo del lado izquierdo que en el lado derecho (13.0). Las células espermáticas tenían colas en loop en mayor cantidad en el epidídimo izquierdo (cabeza, 4.90; cuerpo, 5.30; cola 4.30) que en el lado derecho (cabeza, 4.70; cuerpo, 3.20; cola 5.10). Sin embargo, en la zona caudal del epidídimo derecho el valor promedio fue más alto. En este estudio, en el testículo izquierdo los espermatozoides presentaron más defectos morfológicos (12.96) que en el derecho (12.42). Entre los parámetros epididimarios y testiculares hubo correlación positiva (peso del epidídimo, peso de los testículos y epidídimos, longitud del epidídimo y circunferencias de los testículos y epidídimos p Abstract in english Testicular parameters and morphological characteristics of testicular and epididymal spermatozoa of white Fulani bulls were study using twenty testicles. The objective was to study the normal testicular parameter and morphological changes during epididymal transit in the epididymis of white Fulani b [...] ulls. It was observed that there was reduction in the proportion of spermatozoa carrying the proximal cytoplasmic droplet (PCD) along the epididymis as spermatozoa mature. There were more narrow head in the left (0.40) than the right epididymis (0.10). There was more bent normal tail (16.7) in the left epididymis than in right epididymis (13.0). The sperm cells having looped tails are higher in the left epididymis (caput, 4.90; corpus, 5.30; caudal 4.30) than the right epididymis (caput, 4.70; corpus, 3.20; caudal 5.10) despite the fact that the caudal epididymis in the right epididymis has a higher mean value. In this study the left testicle had more of the morphologically defective spermatozoa (12.96%) than the right testicles (12.42%). The epididymal and testicular parameters were positively correlated (weight of epididymis, weight of estis and epididymis, length of epididymis, circumference of the testes and epididymis, (p

  7. Gynecomastia Following Cytotoxic Therapy in a Patient with Testicular Cancer

    Directory of Open Access Journals (Sweden)

    Bar?? Ak?nc?

    2008-01-01

    Full Text Available Gynecomastia is the development of abnormal breast tissue in men. Relatively increased estrogen action on tissue level is believed to play a main role in the pathogenesis of the entity. Here, we describe a patient with painless gynecomastia presenting after cytotoxic chemotherapy for testicular cancer. Further investigations showed no evidence of disease progression, recurrence, or metastasis. We suggest that the clinicians should be aware that gynecomastia may follow cytotoxic chemotherapy for testicular cancer and does not reflect the return of malignancy. Turk Jem 2008; 12: 86-7

  8. Radionuclide diagnostics of testicular blood flow changes in varicocele

    International Nuclear Information System (INIS)

    Gamma camera scintigraphy is performed in 82 patients presenting varicocele associated with fertility and spermatogenesis impairment. A new method of quantitative and semi-quantitative assessment of testicular blood and vascularity is used to reveal changes in testicular blood flow due to varicocele. The obtained radionuclide indices are typical of the disease, and their numerical values illustrate the changes in the blood vessels and capillary tissue vascularity. The varicocele curve proper has a very characteristic pattern, and enables different diagnosis with focal epididymitis of the head of epididyms. The radionuclide indices and their values are also used to assess the severity of the disease. 5 refs., 4 figs. (orig.)

  9. Quiste laríngeo congénito: Una rara causa de estridor en niños Congenital Laryngeal Cyst: A Rare Cause of Stridor in Children

    Directory of Open Access Journals (Sweden)

    Rodrigo Iñiguez C

    2006-04-01

    Full Text Available Introducción: Los quistes laríngeos congénitos (QLC son una causa rara de estridor en niños. Objetivo: Describir las características clínicas del QLC como responsable de estridor atípico. Caso clínico: Una lactante sana fue evaluada por cuadro agudo de disfonía y estridor asociado a dificultad respiratoria progresiva en ausencia de pródromo respiratorio viral. La nasofibrolaríngoscopía demostró una masa en el ventrículo laríngeo y pliegue aritenoepiglótico izquierdo de 1 cm. La tomografía computada sugirió un QLC único, por lo que se procedió a marsupialización con resección de sus paredes. La evolución fue favorable, con controles posteriores hasta por 3 meses, observando una progresiva disminución del proceso inflamatorio. Conclusiones: Los QLC son una causa de estridor atípico que requieren alta sospecha. Se resalta la necesidad de considerar el estudio anatómico de la vía aérea en todo niño con estridor de curso infrecuenteBackground: Congenital laryngeal cyst (CLC is a rare cause of stridor in children. Objective: To describe the clinical profile of atypical stridor due to CLC. Case report: A healthy infant was admitted for acute dysphonia, stridor and progressive respiratory distress without previous respiratory infection. A nasofiberoptic evaluation showed a laryngeal ventricle and a left aritenoepyglotic mass. The scanner revealed a unique CLC. A marsupialization was performed with resection of the walls. She had a successful ambulatory assessment of 3 months. Conclusion: CLC causes an atypical stridor that requires a high suspicious index. Under special situations, an airway evaluation should be considered as essential for the management

  10. Quiste dermoide en la infancia bajo el diagnóstico de ptosis / Dermoid cyst in chidhood, diagnosed as ptosis

    Scientific Electronic Library Online (English)

    M.E., Correa Pérez; H., Sánchez-Tocino; G., Blanco Mateos.

    2010-06-01

    Full Text Available Caso clínico: Niño de 4 años diagnosticado por su pediatra de ptosis congénita en ojo izquierdo a los 2 años. En su valoración oftalmológica inicial, únicamente se aprecia discreta asimetría entre los párpados superiores. Es en consultas posteriores cuando aparece discreta hipotropia del ojo izquier [...] do, y un astigmatismo creciente que hacen sospechar sobre patología orbitaria. La RMN confirma la presencia de una masa compatible con un quiste dermoide. Conclusión: Debido al crecimiento lento de estos tumores, sólo un seguimiento de la clínica y la ayuda de pruebas de imagen, llevará al diagnóstico y al tratamiento definitivo mediante extirpación quirúrgica. Abstract in english Clinical case: A four year-old boy, diagnosed of palpebral ptosis since he was 2 by his paediatrician. At the initial ophthalmological revies he had asymmetrical upper eyelids. In the follow-up a mild ocular hypotrophy appeared in his left eye and an increasing astigmatism, which made us suspect an [...] orbital disease. The MRI confirmed a mass, compatible with a dermoid cyst. Conclusion: Due to the slow growth of these tumours, it is only with clinical follow-up and the aid of imaging techniques that we may achieve the diagnosis and offer a definitive treatment with surgical extirpation.

  11. Quiste dentígeno gigante en una niña: Presentación de un caso Giant dentigerous cyst in a girl: Case report

    Directory of Open Access Journals (Sweden)

    Juan Carlos Quintana Díaz

    2007-06-01

    Full Text Available Se presenta un caso interesante de una niña de 13 años que acude a la consulta de Cirugía Maxilofacial por presentar asimetría facial y bucal, además de referir diplopia y obstrucción nasal del lado de la deformidad. Después de realizar exámenes de laboratorio, radiográficos y tomografía axial computadorizada (TAC, se lleva al salón de operaciones para realizar extracción del tercer molar superior izquierdo retenido en posición invertida, enuclear la extensa área radiolúcida a los rayos X y radiopaca a la tomografía y posteriormente se realiza estudio histopatológico. El diagnóstico definitivo corroboró el presuntivo (quiste dentígeno . La paciente evolucionó de forma excelente; desaparecieron la deformidad facial y los demás síntomas preoperatorios.An interesting case of a 13 year-old girl comes to Maxillofacial Surgery consultation because she has facial and buccal asymmetry; she also refers diplopia and nasal obstruction on the side of the deformity. After carrying out laboratory exams, radiographic studies and computerized axial tomography (TAC, she was taken to the operating room to receive an extraction of the third left superior molar retained in inverted position, and to have retrieved the extensive rays- X radiolucid and radiopaque area at tomography and later on she underwent a histopathological study. The definitive diagnosis corroborated the presumption of dentition cyst. The patient evolved in an excellent way; her facial deformity and other preoperative symptoms disappeared.

  12. Quiste dentígeno gigante en una niña: Presentación de un caso / Giant dentigerous cyst in a girl: Case report

    Scientific Electronic Library Online (English)

    Juan Carlos, Quintana Díaz; Abdulsalam, Ali Zwiad; Sarah, López Lazo; Sergio, Vega Basulto; Rafael, Pinilla González; Zayed, Hussein.

    2007-06-01

    Full Text Available Se presenta un caso interesante de una niña de 13 años que acude a la consulta de Cirugía Maxilofacial por presentar asimetría facial y bucal, además de referir diplopia y obstrucción nasal del lado de la deformidad. Después de realizar exámenes de laboratorio, radiográficos y tomografía axial compu [...] tadorizada (TAC), se lleva al salón de operaciones para realizar extracción del tercer molar superior izquierdo retenido en posición invertida, enuclear la extensa área radiolúcida a los rayos X y radiopaca a la tomografía y posteriormente se realiza estudio histopatológico. El diagnóstico definitivo corroboró el presuntivo (quiste dentígeno ). La paciente evolucionó de forma excelente; desaparecieron la deformidad facial y los demás síntomas preoperatorios. Abstract in english An interesting case of a 13 year-old girl comes to Maxillofacial Surgery consultation because she has facial and buccal asymmetry; she also refers diplopia and nasal obstruction on the side of the deformity. After carrying out laboratory exams, radiographic studies and computerized axial tomography [...] (TAC), she was taken to the operating room to receive an extraction of the third left superior molar retained in inverted position, and to have retrieved the extensive rays- X radiolucid and radiopaque area at tomography and later on she underwent a histopathological study. The definitive diagnosis corroborated the presumption of dentition cyst. The patient evolved in an excellent way; her facial deformity and other preoperative symptoms disappeared.

  13. A Rare Case of an Epidermoid Cyst in the Parotid Gland - which was Diagnosed by Fine Needle Aspiration Cytology.

    Science.gov (United States)

    Hegde, Panna N; Prasad H L, Kishan; Kumar Y, Sunil; Sajitha, K; Roy, Pooja Sarda; Raju, Mary; Shetty, Vikram

    2013-03-01

    Cystic lesions are common in the head and neck. The most common are the cutaneous cysts, which are referred to as epidermal cysts. These cysts present as nodular and fluctuant subcutaneous lesions and they are seen most commonly in the acne - prone areas like the head, neck and the back. They arise following a localized inflammation of the hair follicle and occasionally after the implantation of the epithelium, following a trauma or surgery. The presence of benign cystic lesions in the salivary glands is rare.We are presenting a rare case of a 55-year-old male who presented with a soft swelling on the left side of the face. A diagnosis of an epidermoid cyst was given on cytology. A superficial parotidectomy was performed and the histopathology confirmed the above diagnosis. PMID:23634420

  14. Profundidad tumoral en el carcinoma epidermoide lingual: Repercusiones diagnósticas / Tumor depth in squamous cell carcinoma of the tongue: Diagnostic repercussions

    Scientific Electronic Library Online (English)

    J.D., Sánchez López; M.A., Sicilia Gutiérrez; L.M., Capitán Cañadas; I., Labrot Moleón; S., Martínez-Villalobos Castillo; E., Valencia Laseca.

    2007-02-01

    Full Text Available Objetivo. Determinar el grado de concordancia entre la valoración clínica (cT) e histopatológica (pT) del tamaño del carcinoma epidermoide lingual en relación a la introducción del parámetro de profundidad tumoral (ppT). Material y métodos. 1) Diseño: Estudio retrospectivo de base hospitalaria const [...] ituido por 60 pacientes evaluados desde Enero de 1990 a Julio de 1997 (Seguimiento mínimo de 8 años). 2) Variables: Filiación del paciente, parámetros clínicos y parámetros histopatológicos. 3) Método estadístico: Correlación mediante el Indice Kappa (p Abstract in english Objective. To determine the degree of concordance between clinical (cT) and histopathological (pT) values for tumor size in squamous cell carcinoma when introducing "tumor thickness" as a diagnostic marker. Materials and methods. 1) Design: A retrospective hospital study of 60 patients evaluated bet [...] ween January 1990 and July 1997 was carried out. 2) Variables: Patient dates, clinical and histopathological parameters. 3) Statistics: Correlation assessment by Kappa Index (p

  15. HISTOLOGIA TESTICULAR HUMANA COMPARADA, ADULTO JOVEN Y SENIL / HUMAN TESTICULAR HISTOLOGY IN YOUNG AND SENILE MEN

    Scientific Electronic Library Online (English)

    Héctor, Rodríguez; Paulina, Salazar; Nadia, Schmidt; Patricia, Torres; Enrique, Ossandón.

    Full Text Available [...] Abstract in english In general, sperm production decreases with advanced age in men. Therefore the present work compares the histology and cellularity of aging human testis with that of a young adult. Gonads from three patients 69 years old and testis from a young subject (aged 25 years) were examined after histologic [...] al standard techniques (PAS-Haematoxyline). Histological, morphometric and cell counting analyses of testicular sections revealed that the seminiferous tubules of senile patients were of smaller diameter, with lower seminiferous epithelium, incomplete germ cell line and vacuolization of the epithelium. Sertoli cells showed a market quantitative decrease, similar to the spermatogonial and primary spermatocyte population. It is possible to postulated that in the senile individues there is a programmed damage of seminiferous epithelial cells that may result in lowered sperm production

  16. Regulación inmuno-testicular y citocinas / Immune-testicular regulation and cytokines

    Scientific Electronic Library Online (English)

    Giovanny, Vivas-A; Jesús, Lozano-H; Judith, Velasco.

    2007-03-01

    Full Text Available La patogénesis de la infertilidad masculina se puede reflejar en una alteración de la espermatogénesis, causada por cáncer testicular, aplasia de las células germinales, varicocele, factores ambientales o defecto en el transporte de los espermatozoides, entre otros. En general, un 48% de hombres cur [...] sa con esterilidad sin causa aparente. Durante mucho tiempo, el tracto reproductor masculino y el sistema inmunológico han sido estudiados como sistemas diferentes e independientes. Sin embargo, en las dos últimas décadas se ha despertado un particular interés por la interacción de ambos sistemas en la infertilidad masculina, con énfasis en la evaluación de anticuerpos antiespermáticos como causa común de infertilidad. Además, la inflamación debida a infecciones genitales o sistémicas puede causar alteraciones en la función testicular. El reconocimiento de los antígenos intratesticulares, provoca la producción de anticuerpos por parte de los linfocitos B. Luego, el sistema inmunológico induce una respuesta celular, mediante la secreción de citoquinas, activación del complemento y activación de los linfocitos T. En la presente revisión se examinarán los componentes y el mecanismo de respuesta del sistema inmunológico, la organización del testículo como órgano reproductor, los mediadores de la respuesta inmunológica: interleucina-1 (IL-1), IL-6 Factor Inhibidor de la Leucemia, Factor de necrosis tumoral ?, Molécula FasL (CD95L) y Fas (CD95), Factor inhibitorio de la migración de macrófagos, Factor Estimulador de las Colonias de Fagocitos Mononucleares y Factor Estimulador de las Colonias de Granulocitos/macrófagos, así como Factor de Células Madres, Interferón, Factor de Transformación y Crecimiento ? y activinas. Abstract in english The pathogenesis of male infertility can be reflected in alterations of spermatogenesis caused by testicular cancer, aplasia of the germinal cells, varicocele, environmental factors or defect in the transport of the sperms, among others. In general, 48% of men suffer unexplained infertility. During [...] a long time, the masculine reproductive tract and the immune system have been studied as different and independent systems. However, in the last two decades a particular interest has arisen in the interaction of both systems on masculine infertility, in particular in the evaluation of antisperm antibodies as a common cause of infertility. Also, the inflammation due to genital or systemic infections can cause alterations in the testicular function. The recognition of intratesticular antigens provokes the production of antibodies by B lymphocytes. Then, the immune system induces a cellular response, by cytokines secretion, activation of complement and T lymphocytes activation. In this review the components and the immune system response mechanism, the organization of the testicle as a reproductive organ and the mediators of the immunologic response will be examined: interleukin-1 (IL-1), IL-6, leukaemia Inhibitory factor, tumor necrosis factor- ?, the molecule FasL (CD95L) and Fas (CD95), macrophage migration-inhibitory factor, mononuclear phagocyte colony stimulating factor, Granulocyte/macrophage colony stimulating factor, as well as stem cell factor, interferon, transforming growth factor B and activins.

  17. Leydig-cell function in children after direct testicular irradiation for acute lymphoblastic leukemia

    International Nuclear Information System (INIS)

    To assess the effect of testicular irradiation on testicular endocrine function, we studied 12 boys with acute lymphoblastic leukemia who had been treated with direct testicular irradiation 10 months to 8 1/2 years earlier. Insufficient Leydig-cell function, manifested by a low response of plasma testosterone to chorionic gonadotropin or an increased basal level of plasma luteinizing hormone (or both), was observed in 10 patients, 7 of whom were pubertal. Two of these patients had a compensated testicular endocrine insufficiency with only high plasma concentrations of luteinizing hormone. Testosterone secretion was severely impaired in three pubertal boys studied more than four years after testicular irradiation. A diminished testicular volume indicating tubular atrophy was found in all pubertal patients, including three who had not received cyclophosphamide or cytarabine. These data indicate that testosterone insufficiency is a frequent complication of testicular irradiation, although some patients continue to have Leydig-cell activity for several years after therapy

  18. Leydig-cell function in children after direct testicular irradiation for acute lymphoblastic leukemia

    Energy Technology Data Exchange (ETDEWEB)

    Brauner, R.; Czernichow, P.; Cramer, P.; Schaison, G.; Rappaport, R.

    1983-07-07

    To assess the effect of testicular irradiation on testicular endocrine function, we studied 12 boys with acute lymphoblastic leukemia who had been treated with direct testicular irradiation 10 months to 8 1/2 years earlier. Insufficient Leydig-cell function, manifested by a low response of plasma testosterone to chorionic gonadotropin or an increased basal level of plasma luteinizing hormone (or both), was observed in 10 patients, 7 of whom were pubertal. Two of these patients had a compensated testicular endocrine insufficiency with only high plasma concentrations of luteinizing hormone. Testosterone secretion was severely impaired in three pubertal boys studied more than four years after testicular irradiation. A diminished testicular volume indicating tubular atrophy was found in all pubertal patients, including three who had not received cyclophosphamide or cytarabine. These data indicate that testosterone insufficiency is a frequent complication of testicular irradiation, although some patients continue to have Leydig-cell activity for several years after therapy.

  19. Linfoma testicular primario: Aportación de un nuevo caso y revisión de la literatura / Primary testicular lymphoma: Contribution of one case and literature review

    Scientific Electronic Library Online (English)

    I., Gómez García; R., Rodríguez Patrón; E., Sanz Mayayo; J.M., Rodríguez Luna; A., Palmeiro Uriach; S., Conde Someso; F.J., Burgos Revilla; D., García Ortells; A., Escudero Barrilero.

    2004-02-01

    Full Text Available El linfoma testicular primario es un tumor testicular infrecuente, suponiendo no más del 9% de los tumores testiculares en las series con mayor incidencia; a su vez el linfoma testicular como tumor hematopoyético es infrecuente, con una incidencia del 1% de los linfomas, pero debido a su histopatolo [...] gía en la mayoría de los casos de alta malignidad, les hace ser de los tumores testiculares más agresivos. La edad de aparición es por encima de los 60 años, convirtiéndose en el tumor más frecuente para este grupo de edad. La falta de series amplias, hace que no exista un protocolo establecido para el tratamiento de esta patología. Presentamos un nuevo caso, realizando revisión de la bibliografía presentando las tendencias terapéuticas actuales para este tipo de patología. Abstract in english Primary testicular lymphoma is an uncommon testicular tumour that accounts for no more than 9% of all testicular tumours in those series with higher incidence; testicular lymphoma as haematopoietic tumours are also rare accounting for just 1% of all lymphomas; but due to their highly malignant histo [...] pathology they may become highly aggressive tumours. Patient age at presentation is over 60 years old which makes it the most frequent tumour for this age group. There is no standard protocol to treat this malignancy due to lack of extensive series. We contribute one case and make a literature review discussing the current therapeutic trends for this disease.

  20. OPTIMIZACIÓN EN LA ESTRATEGIA DIAGNÓSTICA Y TERAPÉUTICA EN EL QUISTE DE COLÉDOCO / Optimization in diagnostic and therapeutic strategy of choledochal cyst

    Scientific Electronic Library Online (English)

    Grecia Victoria, Vivas-Colmenares; Ana, Millán-López; Juan Carlos, De Agustín A.

    2015-06-01

    Full Text Available Objetivos: El quiste de colédoco presenta una incidencia de 1 en 100.000-150.000. El propósito de este estudio fue analizar las variables introducidas para la optimización en el diagnóstico y tratamiento del quiste de colédoco. Material y Métodos: Estudio retrospectivo de pacientes intervenidos en n [...] uestro centro de quiste de colédoco mediante hepático-yeyunostomía en Y de Roux, desde septiembre de 1988 a noviembre de 2012. Se analizan 40 variables incluyendo edad, sintomatología, tipo de quiste, pruebas diagnósticas, cambios en la técnica quirúrgica, complicaciones y evolución. Resultados: 18 pacientes (66,6% mujeres) fueron agrupados de acuerdo a la edad de presentación: Prenatal ( 24 meses). Los síntomas más frecuentes fueron ictericia y dolor abdominal (para los de inicio precoz y tardío respectivamente). El 83,3% presentaban quistes de colédoco tipo I; siendo suficiente la ecografía para el diagnóstico en el 94,4%. A partir de 2004 modificamos la técnica quirúrgica, realizando por vía laparoscópica la disección de la vía biliar y mediante laparotomía mínima (3-5 cm) hepático-yeyunostomía con asa descendente de 40 cm, empleando sutura de polipropileno, observando desde el 2004, sólo 1 dehiscencia parcial de la anastomosis, resuelta con tratamiento conservador y 1 colangitis en paciente con poliquistosis hepática y renal. En el año 2012 el 83,3% están asintomáticos. Conclusiones: El diagnóstico se ha simplificado, en más de 90% de los casos se realiza sólo con ecografía; los avances en cirugía mínimamente invasiva y la creación de asa descendente de 40 cm, han logrado optimizar el pronóstico del quiste de colédoco. Abstract in english Objectives: The choledochal cyst has an incidence of 1 in 100.000-150.000. The purpose of this study was to analyze the variables introduced for the optimization in the diagnosis and treatment of choledochal cyst. Material and Methods: Retrospective study of patients treated in our center by hepatic [...] -jejunostomy and Roux-Y, from September 1988 to November 2012. We analyzed 40 variables including age, symptoms, type of cysts, diagnostic tests, changes in surgical technique, complications and outcomes. Results: Eighteen patients (66.6% female) were grouped according to the age of presentation: Prenatal ( 24 months). The most common symptoms were jaundice and abdominal pain (for early-onset and late-onset respectively). The 83.3% presented choledochal cysts type I, the ultrasound was sufficient for diagnosis in 94.4%. Since 2004 we modified the surgical technique, performing laparoscopic dissection of the bile duct and cyst, adding a mini-laparotomy (3-5 cm) for hepatic-jejunostomy with 40 cm intestinal loop using polypropylene suture. One complication was observed since 2004, one case of partial dehiscence of the anastomosis resolved with conservative treatment and a cholangitis in 1 patient with hepatic and renal polycystic. In 2012, 83.3% are asymptomatic. Conclusions: The diagnostic have been simplified, in more than 90% of cases was done by ultrasound; advances in minimally invasive surgery and creation of descending loop of 40 cm, have helped to improve the prognosis of choledochal cyst.

  1. Metabolic fingerprints in testicular biopsies from type 1 diabetic patients.

    Science.gov (United States)

    Alves, Marco G; Martins, Ana D; Moreira, Paula I; Carvalho, Rui A; Sousa, Mário; Barros, Alberto; Silva, Joaquina; Pinto, Soraia; Simões, Teresinha; Oliveira, Pedro Fontes

    2015-11-01

    Diabetes mellitus (DM) is a metabolic disease that has grown to pandemic proportions. Recent reports have highlighted the effect of DM on male reproductive function. Here, we hypothesize that testicular metabolism is altered in type 1 diabetic (T1D) men seeking fertility treatment. We propose to determine some metabolic fingerprints in testicular biopsies of diabetic patients. For that, testicular tissue from five normal and five type 1 diabetic men was analyzed by high-resolution magic-angle spinning (HR-MAS) nuclear magnetic resonance (NMR) spectroscopy. mRNA and protein expression of glucose transporters and glycolysis-related enzymes were also evaluated. Our results show that testes from diabetic men presented decreased levels of lactate, alanine, citrate and creatine. The mRNA levels of glucose transporter 1 (GLUT1) and phosphofructokinase 1 (PFK1) were decreased in testes from diabetic men but only GLUT3 presented decreased mRNA and protein levels. Lactate dehydrogenase (LDH) and glutamate pyruvate transaminase (GPT) protein levels were also found to be decreased in testes from diabetic men. Overall, our results show that T1D alters glycolysis-related transporters and enzymes, compromising lactate content in the testes. Moreover, testicular creatine content was severely depressed in T1D men. Since lactate and creatine are essential for germ cells development and support, the data discussed here open new insights into the molecular mechanism by which DM promotes subfertility/infertility in human males. PMID:26051285

  2. An infant with testicular torsion in the inguinal canal

    Energy Technology Data Exchange (ETDEWEB)

    Candocia, Fabian J.; Sack-Solomon, Kathryn [Jacobi Medical Center, Albert Einstein College of Medicine, 1400 Pelham Parkway, Room 4N15, Bronx, NY 10461 (United States)

    2003-10-01

    We report a case of testicular torsion in the left inguinal canal of a 7 month old with a history of cryptorchism and no evidence of neuromuscular disease. We discuss the pathophysiological mechanisms, sonographic findings, and treatment of this rare entity. (orig.)

  3. An infant with testicular torsion in the inguinal canal

    International Nuclear Information System (INIS)

    We report a case of testicular torsion in the left inguinal canal of a 7 month old with a history of cryptorchism and no evidence of neuromuscular disease. We discuss the pathophysiological mechanisms, sonographic findings, and treatment of this rare entity. (orig.)

  4. The effect of the melatonin on cryopreserved mouse testicular cells

    Directory of Open Access Journals (Sweden)

    Ghasem Saki

    2016-01-01

    Full Text Available Background: After improvements in various cancer treatments, life expectancy has been raised, but success in treatment causes loss of fertility in many of the survived young men. Cryopreservation of immature testicular tissues or cells introduced as the only way to preserve fertility. However, freezing has some harmful effects. Melatonin, a pineal gland hormone, has receptors in reproductive systems of different species. It is assumed that melatonin has free radical scavenger properties. Objective: The aim of this study was to evaluate the effects of melatonin on the cryopreserved testicular cells in mouse. Materials and Methods: Cells from 7- 10 days old NMRI mice testes were isolated using two step enzymatic digestion. The testicular cells were divided into two groups randomly and cryopreserved in two different freezing media with and without the addition of 100 μm melatonin. Finally, apoptosis of the cells was assayed by flow cytometry. Also, lactate dehydrogenase activity test was performed to assess the cytotoxicity. Results: The results of lactate dehydrogenase showed the nearly cytotoxic effect of melatonin. The results of flow cytometry showed increase in apoptosis in the cryopreserved cells in the media containing melatonin compared to the control group. Conclusion: The present study shows that melatonin has an apoptotic effect on cryopreserved mouse testicular cells.

  5. Testicular torsion in a patient with Cohen syndrome.

    Science.gov (United States)

    Y?lmaz, Ömer; Ye?ildal, Cumhur; Malkoç, Ercan; Soydan, Hasan

    2015-03-01

    Cohen syndrome is an extremely rare autosomal recessive disorder. A 12-year-old boy with Cohen syndrome applied to a primary health care center because of severe pain in the left groin and was diagnosed with epididymo-orchitis. Despite the administered the antibiotic treatment, pain increased. Therefore, the family brought the patient to the emergency department 16 h after the first diagnosis. The patient had mild mental retardation, myopia, and craniofacial dysmorphism, which are components of Cohen syndrome. There was no blood flow on the left testicle at color Doppler ultrasonography. Further, scrotal exploration was performed because of a high risk of torsion. The left testicle was torsioned, and the color was dark blue. Revascularization could not be achieved by detorsion; left orchiectomy and right testicular fixation were then conducted. In conclusion, to the best of our knowledge, this is the first reported case of testicular torsion in Cohen syndrome. If a patient with this syndrome has acute groin pain, testicular torsion should be immediately ruled out with Doppler ultrasonography. These patients may not clearly and correctly express themselves because of mild mental retardation. Moreover, detailed genitourinary, particularly testicular examination may clarify the omitted pathologies and make them well known in future in this syndrome. PMID:26328200

  6. Quiste coloide del tercer ventrículo. Presentación de un caso: una nueva alternativa en el tratamiento de las ectasias / Colloidal cyst of the third ventricle. Case presentation

    Scientific Electronic Library Online (English)

    Ada, Sánchez Lozano; María, Rodríguez Roque; Joan, Rojas Fuentes.

    2009-08-01

    Full Text Available Los quistes coloides son lesiones intracraneales congénitas benignas, de la porción antero-superior del tercer ventrículo. Suponen del 0,2 al 2 % de todos los tumores intracraneales y representan del 15 al 20 % de todas las masas intraventriculares. Comienzan a ser sintomáticos en la adolescencia o [...] edad adulta temprana, generalmente con manifestaciones de cefalea o síntomas de hipertensión intracraneal al provocar hidrocefalia obstructiva. Se presenta una adolescente de 18 años con historia de cefalea de 2 años de evolución, cuyos síntomas fueron empeorando en intensidad y frecuencia, acompañados de vómitos y parestesias bilaterales; se le diagnosticó hidrocefalia obstructiva con quiste coloide del tercer ventrículo. Ante la sospecha del diagnóstico se tomó una conducta adecuada, para evitar el deterioro neurológico y la muerte. Se discutieron las principales características del quiste coloide, su cuadro clínico y radiológico. Abstract in english Colloidal cysts are congenital intracranial benign lesions of the anterior superior portion of the third ventricle. They represent between the 0,2 and 2 % of all the intracranial tumours and represent the 15 or 20 % of all the intraventricular masses. They become symptomatic during the adolescence o [...] r early adulthood and start normally with migraine or symptoms of intracranial hypertension causing obstructive hydrocephaly. We present the case of a teenager of 18 years of age with history of migraine after two years and the symptoms worsened in intensity and frequency including vomiting and bilateral paresthesia; the diagnosis was obstructive hydrocephaly with colloidal cyst of the third ventricle. An appropriate practice was adopted due to the uncertain diagnosis in order to avoid neurological damage and death. We discussed the main characteristics of the colloidal cyst, its clinical presentation and radiological characteristics and we performed.

  7. Fractura patológica de la mandíbula asociada a quiste radicular: Reporte de 3 casos clínicos Mandibular pathologic fracture associated with radicular cyst: Report of three clinical cases

    Directory of Open Access Journals (Sweden)

    J. Bouguila

    2008-08-01

    Full Text Available Introducción. El quiste radicular es el quiste más común de los maxilares. Su tamaño puede variar desde una lesión que abarca el proceso alveolar hasta uno extenso que oblitera el espacio antral maxilar o causa una fractura patológica mandibular. Reporte de casos. Se reportan tres casos con fractura patológica mandibular asociados a quiste radicular ocurridos después de trauma facial. El diagnóstico fue sugerido por un estudio clínico, radiografía panorámica y confirmado por el estudio histopatológico de la pieza operatoria. El tratamiento consistió en enucleación quística seguido por inmovilización de fragmentos con osteosíntesis o bloqueo intermaxilar. El resultado clínico y radiológico a corto plazo fue favorable. Discusión. Se discuten aspectos propios de la patología y su terapia. Conclusión. El éxito del tratamiento depende de una adecuada terapia en que sus principios más importantes son la remoción de la lesión mediante enucleación y una fijación estable.Introduction. Radicular cyst is the most common cyst of the oral cavity. It may range in size from a small periapical lesion to one that can obliterate the antral space or cause mandibular fracture. Case reports. We report three cases of radicular cyst complicated by mandibular fracture that occurred after maxillofacial trauma. The diagnosis was strongly suggested by panoramic radiography and confirmed by pathology examination of the operative specimen. Treatment consisted in cyst enucleation followed by immobilization of fragments by osteosynthesis or maxillomandibular fixation. The clinical and radiologic outcome was favorable. Discussion. The particularities and treatment are discussed. Conclusion. Treatment success is dependent on adequate therapy, the principles of which are removing the lesion and providing stable fixation.

  8. Fractura patológica de la mandíbula asociada a quiste radicular: Reporte de 3 casos clínicos / Mandibular pathologic fracture associated with radicular cyst: Report of three clinical cases

    Scientific Electronic Library Online (English)

    J., Bouguila; L., Córdova Jara; I., Zairi; A., Adouani.

    2008-08-01

    Full Text Available Introducción. El quiste radicular es el quiste más común de los maxilares. Su tamaño puede variar desde una lesión que abarca el proceso alveolar hasta uno extenso que oblitera el espacio antral maxilar o causa una fractura patológica mandibular. Reporte de casos. Se reportan tres casos con fractura [...] patológica mandibular asociados a quiste radicular ocurridos después de trauma facial. El diagnóstico fue sugerido por un estudio clínico, radiografía panorámica y confirmado por el estudio histopatológico de la pieza operatoria. El tratamiento consistió en enucleación quística seguido por inmovilización de fragmentos con osteosíntesis o bloqueo intermaxilar. El resultado clínico y radiológico a corto plazo fue favorable. Discusión. Se discuten aspectos propios de la patología y su terapia. Conclusión. El éxito del tratamiento depende de una adecuada terapia en que sus principios más importantes son la remoción de la lesión mediante enucleación y una fijación estable. Abstract in english Introduction. Radicular cyst is the most common cyst of the oral cavity. It may range in size from a small periapical lesion to one that can obliterate the antral space or cause mandibular fracture. Case reports. We report three cases of radicular cyst complicated by mandibular fracture that occurre [...] d after maxillofacial trauma. The diagnosis was strongly suggested by panoramic radiography and confirmed by pathology examination of the operative specimen. Treatment consisted in cyst enucleation followed by immobilization of fragments by osteosynthesis or maxillomandibular fixation. The clinical and radiologic outcome was favorable. Discussion. The particularities and treatment are discussed. Conclusion. Treatment success is dependent on adequate therapy, the principles of which are removing the lesion and providing stable fixation.

  9. Diagnóstico por imagen de un quiste hidatídico pulmonar gigante. Reporte de un caso clínico / Diagnostic imaging of a giant pulmonary hydatid cyst. Clinical Case Report

    Scientific Electronic Library Online (English)

    Ifigenia, Oviedo Gamboa; Boris Jorge, Castillo Yujra; William, Zegarra Santiesteban; José Luis, Llanos Fernández.

    2013-06-01

    Full Text Available La Hidatidosis o equinococcosis es una enfermedad clasificada dentro de las ciclozoonosis. Es producida por las formas larvarias de Echinococcus granulosus que parasita el intestino del perro. Los quistes hidatídicos poseen como segunda localización el pulmón en un 10%. Se presenta el caso clínico d [...] e una paciente de 82 años de edad que presento un cuadro clínico de 1 mes de evolución caracterizado por accesos de tos productiva verdosa, escalofríos, alzas térmicas , al examen físico se auscultó murmullo vesicular disminuido en campo pulmonar izquierdo. Se realizó radiografía de tórax inconclusas donde se evidencio dos imágenes radiopacas circulares, homogéneas , en cuadrante superior e inferior de campo pulmonar izquierdo. La tomografía multicorte informo quistes pulmonares gigantes en he-mitorax izquierdo, se realizo toracotomía exploratoria y quistectomia, finalmente la patología confirmo quistes hidatídicos pulmonares gigantes y proceso inflamatorio crónico activo. Abstract in english Hydatidosis or echinococcosis is a disease classified within ciclozoonosis. It is produced by the larval forms of Echinococcusgranulosus that parasitizes the intestine of the dog. Hydatid cysts cover the lung with 10%, beeingthe second location. This is a case report of a patient of 82 years old who [...] had a 1 month clinical evolution characterized by greenish productive coughing, chills, heat rises , physical examination decreased breath sounds auscultated in left lung field, The X ray (unfinished) evidenced two circular homogeneousradio-pacities upper quadrant and lower left lung field, multislice CT reported giant lung cysts, exploratory thoracotomy and cystectomy was performed, finally pathology confirmed pulmonary giant hydatid cysts and active chronic inflammatory process.

  10. ¿Los quistes renales simples son otra forma de manifestación de prelitiasis en la infancia? / Are simple renal cysts another manifestation of prelithiasis in infancy?

    Scientific Electronic Library Online (English)

    Víctor, García Nieto; K., Dublan García; M.I., Luis Yanes.

    Full Text Available Los quistes renales simples son lesiones poco frecuentes en pacientes pediátricos. En ausencia de hipopotasemia o de un incremento en la producción de NH4+, se desconoce el origen de los mismos. Hepler, en 1930, propuso que su causa podría ser una obstrucción tubular. Hemos estudiado de forma prospe [...] ctiva la presencia de hipercalciuria o de hipocitraturia, así como los antecedentes familiares de litiasis en un grupo de niños diagnosticados ecográficamente de quistes renales simples. Al diagnóstico, la edad media de los 22 pacientes (12 varones y 10 mujeres) fue de 6,04 ± 2,9 años. El estudio ecográfico se había solicitado por infección de vías urinarias, dolor abdominal, hematuria u otros. Los quistes fueron ligeramente más frecuentes en el lado izquierdo (54,5%). Todos estaban ubicados en el polo renal superior. En 14 pacientes (63,6%) se demostró que eran portadores de hipercalciuria o hipocitraturia (hipercalciurian = 11, 50%). En 13 familias existían antecedentes de litiasis renal. En conjunto, las anomalías metabólicas estudiadas causantes de cálculos en los niños o los antecedentes familiares de litiasis estaban presentes en 19 familias (86,3%). Nuestra hipótesis es que ambas entidades, quistes renales y predisposición genética a padecer cálculos renales, están relacionadas. Abstract in english Simple renal cysts are uncommon lesions in paediatric patients. In the absence of hypokalaemia or an increase in the production of NH+, the cause of simple renal cysts is unknown. Hepler, in 1930, suggested that they may be caused by a tubular obstruction. We prospectively studied the presence of hy [...] percalciuria or hypocitraturia as well as the family history of urolithiasis in a group of children diagnosed sonographically with simple renal cysts. The average age of the 22 patients (12M, 10F) was 6.04 ± 2.9 years at the time of diagnosis. The ultrasound examination had been requested due to urinary tract infection, abdominal pain, haematuria or other disorders. The cysts were slightly more frequent on the left side (54.5%). All were located in the upper kidney pole. 14 patients were found to have hypercalciuria and/or hypocitraturia (hypercalciuria n = 11, 50%). Thirteen families had history of renal stones. The metabolic abnormalities associated with calculi in children and/or family history of stones were present in 19 families (86.3%). Our hypothesis is that both entities, renal cysts, and genetic predisposition to kidney stones, are related.

  11. Quiste dermoide paratesticular: Aportación de un caso y revisión de la literatura / Paratesticular dermoid cyst: Presentation of one case and bibliographic revision

    Scientific Electronic Library Online (English)

    J.I., Luque Arana; C., Salas Antón; J.A., Diez Diez; L., Menéndez Ondina; J., Carballido Rodríguez.

    2003-03-01

    Full Text Available Se presenta un caso de un quiste dermoide que depende de las estructuras paratesticulares, entidad clínica de baja frecuencia de presentación. Se analiza la controvertida terminología de estos tumores y se establecen los criterios anatomopatológicos de esta enfermedad que preside el diagnóstico. [...] Abstract in english It is discussed a dermoid cyst case thath depends on paratesticular structures, clinical entity which has low frecuency of presentation. It is analyced the controversial terminology of this tumours and are established anatomopathological criteria for this disease. [...

  12. Tratamiento de quiste dentígero bilateral mandibular por medio de dos tipos de tratamientos: Relato de caso clínico y comparación entre las técnicas

    Scientific Electronic Library Online (English)

    Marvis E, Allais de Maurette; Paul E, Maurette O’Brien; Francisco, Haiter-Neto; Márcio, de Moraes.

    2007-01-01

    Full Text Available Os cistos dentígeros são o segundo tipo mais comun de lesão cística de desenvolvimento na mandíbula e tem sido associado com a retenção dos terceiros molares. São poucos os relatos de cistos dentígeros bilaterais ou multiplos em pacientes não sindrómicos. Seu tratamento pode ser por meio de enucleaç [...] ão ou descompresão e esta determinado principalmente pelo tamanho da lesão. Algun trabalhos relatam o tratamento dos cistos dentígeros porém não encontramos na literatura nenhum comparando ambos os tratamentos. Neste trabalho relatamos um caso de cisto dentígero bilateral num paciente não sindrómico onde se realizou como tratamento, do lado esquerdo descompresão e do lado direito enucleação, com un acompanhamento pós-operatório de 5 anos consecutivos, sem observar recidiva da lesão. Abstract in spanish Los quistes dentígeros son el segundo tipo mas común de lesión quística de desarrollo en la mandíbula y han sido asociados con la retención de los terceros molares. Son pocos los reportes sobre quistes dentígeros bilaterales o múltiples en pacientes no sindrómicos. Su tratamiento puede ser por medio [...] de la enucleación o descompresión y este es determinado principalmente por el tamaño de la lesión. Algunos artículos hablan del tratamiento de los quistes dentígeros pero no encontramos en la literatura ninguno comparando ambos tratamientos. En este artículo reportamos un caso de quiste dentígero bilateral en un paciente no sindrómico en el cual se realizó como tratamiento, del lado izquierdo descompresión y del lado derecho enucleación, con un acompañamiento posterior de 5 años consecutivos, sin observarse recidiva de la lesión. Abstract in english Dentigerous cyst are the second most common developmental cyst of the jaws and its been associated with impacted third molar teeth. Its rare reports about bilateral or multiple dentigerous cysts in nonsyndromic patients. They treatment can be enucleation or decompression and must be predicated upon [...] the size of lesion. Some articles talk about treatment of dentigerous cyst but we don’t find any one comparing both treatments. Here, we report a case of bilateral nonsyndromic dentigerous cyst comparing the treatment decompression vs. enucleation and follow up for 5 years, without recurrence.

  13. Quiste odontogénico calcificante asociado con odontoma complejo: Presentación de un caso y revisión bibliográfica / Calcifying odontogenic cyst associated with complex odontoma: Case report and review of the literature

    Scientific Electronic Library Online (English)

    Silvia, Gallana Alvarez; Francisco, Mayorga Jimenez; Francisco Javier, Torres Gómez; Francisco Javier, Avellá Vecino; Clara, Salazar Fernandez.

    2005-07-01

    Full Text Available Se presenta un caso de quiste odontogénico calcificante asociado con odontoma (QOCaO) y con un canino permanente incluido en maxilar superior, en un paciente varón de 19 años. El Quiste Odontogénico Calcificante (QOC) fue descrito por primera vez cómo una entidad patológica por Gorlin y col. en 1962 [...] . Se trata de un tumor benigno odontogénico mixto,y aunque la mayoria de estas lesiones presentan características quísticas en algunos casos se presenta como una masa sólida (15 %), y su transformación maligna está bien documentada. El QOC se presenta en ocasiones asociado a otros tumores odontogénicos, el más común es el odontoma al que aparece relacionado en el 24% de los casos. Para esta asociación se ha sugerido el término de "Quiste Odontogénico Odontocalcificante". Radiológicamente es una lesión mixta, bien definida y que histológicamente consiste en un gran quiste en cuya parte central existe un área sólida con acúmulos de esmalte y dentina distribuidos irregularmente en algunas zonas y en otros lugares adopta un aspecto organoide bien definido. Se efectúa una revisión de la literatura y se discute su patogénesis. Abstract in english We report a calcifying odontogenic cyst associated with odontoma (COCaO) and an included permanent canine in the superior maxilla, in a 19 year-old-man. The calcifying odontogenic cyst (COC) was first described as a distinct entity by Gorlin et al in 1962. The lesion is a mixed odontogenic benign tu [...] mor, and although most of the cases present cystic characteristics, a few are of the solid type (15%), and its rare malignant transformation is well documented. The COC may occur in association with other odontogenic tumors, the most common is the odontoma, occurring in about 24% of the cases. For this association the term Odontocalcifying odontogenic cyst has been suggested. Radiographically is a well defined mixed lesion and histologically consists of a large cyst. In the central area of the cyst enamel and dentin deposits can be found, irregularly distributed in areas and in other parts it takes on a well defined organoid aspect. A thorough review of literature takes place and the pathogenesis is discussed.

  14. Quiste gigante de la glándula de Bartolino: reporte de caso y revisión de la literatura A case report and literature review regarding giant Bartholin gland cyst

    Directory of Open Access Journals (Sweden)

    ??dgar E Rivas-Perdomo

    2010-12-01

    Full Text Available Introducción: en el presente artículo se expone el caso de una paciente que tuvo un quiste gigante de la glándula de Bartolino, el cual alcanzó un diámetro de 10 cm. La paciente presentó algunas dificultades diagnósticas y terapéuticas por lo que fue necesaria la escisión de la glándula y la posterior reconstrucción de la vulva. El diagnóstico definitivo fue establecido por anatomía patológica. El caso se presenta con el objetivo de realizar una revisión de la literatura respecto al tratamiento. Materiales y métodos: se realizó una búsqueda de la literatura relacionada con el tema en las bases de datos electrónicas PubMed, SciELO, ScienceDirect y MD Consult, utilizando las palabras clave: "glándulas de Bartolino", "quistes" y "marsupialización". Además, se revisaron referencias de libros de textos. Conclusiones: la urgencia en el tratamiento depende de los síntomas de la paciente. Un quiste asintomático podría no requerir tratamiento. Sin embargo, la no mejoría dentro de las primeras 72 horas o la evolución hacia una forma de absceso requerirá un tratamiento quirúrgico de emergencia. Se ha descrito una amplia variedad de tratamientos que incluyen una serie de procedimientos quirúrgicos tales como: 1 incisión simple y drenaje, 2 fistulización o marsupialización, 3 colocación de un catéter de Word, 4 escleroterapia con alcohol, 5 aplicación de nitrato de plata y 6 ablación del quiste utilizando dióxido de carbono (CO2 con láser.Introduction: the case of a patient who had a giant Bartholin gland cyst is presented; it reached 10 cm diameter, presenting some diagnostic and therapeutic difficulties, requiring the excision of the gland and later reconstruction of the vulva. Definitive diagnosis was established by pathological anatomy. The case is presented as it led to a review of the pertinent literature regarding the relevant treatment. Materials and methods: a search was made of the pertinent literature in PubMed, SciELO, ScienceDirect and MD Consult databases, using the key words "Bartholin glands", "cysts", "marsupialization". Pertinent reference books were also reviewed. Conclusions: the urgency of treatment depends on a particular patient's treatment. An asymptomatic cyst may not require treatment; however, if there is no improvement within the first 72 hours or it evolves towards an abscess, then it will require emergency surgical treatment. A broad variety of treatments has been described which includes a series of surgical procedures, which include: simple incision and drainage, fistulization or marsupialization, placing a Word catheter, sclerotherapy with alcohol, applying silver nitrate and cyst ablation using carbon dioxide (CO2 laser.

  15. Quiste gigante de la glándula de Bartolino: reporte de caso y revisión de la literatura / A case report and literature review regarding giant Bartholin gland cyst

    Scientific Electronic Library Online (English)

    Édgar E, Rivas-Perdomo.

    2010-12-01

    Full Text Available Introducción: en el presente artículo se expone el caso de una paciente que tuvo un quiste gigante de la glándula de Bartolino, el cual alcanzó un diámetro de 10 cm. La paciente presentó algunas dificultades diagnósticas y terapéuticas por lo que fue necesaria la escisión de la glándula y la posteri [...] or reconstrucción de la vulva. El diagnóstico definitivo fue establecido por anatomía patológica. El caso se presenta con el objetivo de realizar una revisión de la literatura respecto al tratamiento. Materiales y métodos: se realizó una búsqueda de la literatura relacionada con el tema en las bases de datos electrónicas PubMed, SciELO, ScienceDirect y MD Consult, utilizando las palabras clave: "glándulas de Bartolino", "quistes" y "marsupialización". Además, se revisaron referencias de libros de textos. Conclusiones: la urgencia en el tratamiento depende de los síntomas de la paciente. Un quiste asintomático podría no requerir tratamiento. Sin embargo, la no mejoría dentro de las primeras 72 horas o la evolución hacia una forma de absceso requerirá un tratamiento quirúrgico de emergencia. Se ha descrito una amplia variedad de tratamientos que incluyen una serie de procedimientos quirúrgicos tales como: 1) incisión simple y drenaje, 2) fistulización o marsupialización, 3) colocación de un catéter de Word, 4) escleroterapia con alcohol, 5) aplicación de nitrato de plata y 6) ablación del quiste utilizando dióxido de carbono (CO2 ) con láser. Abstract in english Introduction: the case of a patient who had a giant Bartholin gland cyst is presented; it reached 10 cm diameter, presenting some diagnostic and therapeutic difficulties, requiring the excision of the gland and later reconstruction of the vulva. Definitive diagnosis was established by pathological a [...] natomy. The case is presented as it led to a review of the pertinent literature regarding the relevant treatment. Materials and methods: a search was made of the pertinent literature in PubMed, SciELO, ScienceDirect and MD Consult databases, using the key words "Bartholin glands", "cysts", "marsupialization". Pertinent reference books were also reviewed. Conclusions: the urgency of treatment depends on a particular patient's treatment. An asymptomatic cyst may not require treatment; however, if there is no improvement within the first 72 hours or it evolves towards an abscess, then it will require emergency surgical treatment. A broad variety of treatments has been described which includes a series of surgical procedures, which include: simple incision and drainage, fistulization or marsupialization, placing a Word catheter, sclerotherapy with alcohol, applying silver nitrate and cyst ablation using carbon dioxide (CO2) laser.

  16. Desenvolvimento testicular, espermatogênese e concentrações hormonais em touros Angus Testicular development, spermatogenesis and hormonal concentrations in Angus bulls

    Directory of Open Access Journals (Sweden)

    Gyselle Viana Aguiar

    2006-08-01

    Full Text Available Este estudo foi realizado com a finalidade de avaliar a evolução das secreções hormonais e do epitélio seminífero em touros da raça Angus de 10 a 38 semanas de idade. Foram castrados 1 a 5 animais em intervalos de quatro semanas (total de 25 touros para coleta de amostras do parênquima testicular e do plasma sanguíneo. As variáveis relacionadas ao crescimento testicular, aos aspectos quantitativos da espermatogênese e aos níveis hormonais foram transformadas em logaritmo e avaliadas por meio de análise de variância. O diâmetro dos testículos e túbulos seminíferos e o peso testicular apresentaram variações mais acentuadas após 26 semanas de idade. A porcentagem do parênquima testicular ocupado pelos túbulos seminíferos aumentou de 49,3 para 75,2% durante o experimento. A maioria dos túbulos (>90% apresentou-se com células de Sertoli somente entre 10 e 14 semanas, mas na 18ª (13,8±1,7% e 22ª semanas (19±1%, o número de túbulos com gonócitos e espermatogônias aumentou em relação às semanas iniciais. Espermatogônias intermediárias e B predominaram na 26ª semana (24,5±8,2% e a porcentagem de túbulos com espermatócitos foi mais elevada na 30ª semana (42,3±9,9%. Espermátides arredondadas foram detectadas partir da 26ª semana e, na 38ª semana, 62,3±1,5% dos túbulos seminíferos continham espermátides alongadas ou maduras. As variações mais acentuadas no crescimento testicular e, principalmente, no peso testicular após as 26 semanas coincidiram com o estabelecimento da meiose, com as alterações morfológicas do núcleo e nucléolo das células de Sertoli (indicativos do processo de diferenciação das mesmas, com os níveis reduzidos de androstenediona e os incrementos significativos de testosterona e estradiol 17beta. As associações entre o crescimento testicular e os níveis de FSH e LH na circulação periférica foram menos evidentes.This study aimed to evaluate changes in hormone secretion and in seminiferous epithelium of Angus bulls between 10 and 38 weeks of age. Samples of testicular parenchyma and blood were collected from 25 animals castrated in 4 week intervals. Traits associated to testicular development and quantitative aspects of spermatogenesis and hormonal concentrations were transformed by logarithm before analyses of variance. Changes in testis and seminiferous tubule diameter and testis weight were more pronounced after 26 weeks of age. The percentage of testicular parenchyma occupied by seminiferous tubules increased from 49.3 to 75.2% from 10 to 38 weeks. Most tubules (>90% had only Sertoli cells at 10 and 14 weeks, but the number of tubules with gonocytes and A spermatogonia increased at 18 (13.8±1.7% and 22 weeks (19±1%. Tubules with B and intermediate spermatogonia became predominant at 26 weeks (24.5±8.2% and those with spermatocytes as the most advanced germ cell type were more evident at 30 weeks (42.3±9.9%. Round spermatids were detected at 26 weeks and at 38 weeks of age, 62.3±1.5% of all tubules had either elongate or mature spermatids. Variations in testis growth (specially testis weight after 26 weeks were coincident with the establishment of meiosis in the seminiferous tubules, morphological alterations in nucleus and nucleolus of the Sertoli cells (indicators of Sertoli cell differentiation, lower levels of androstenedione and significant increases in testosterone and estradiol 17beta. Associations between testis development and concentrations of FSH and LH were less evident.

  17. Desenvolvimento testicular, espermatogênese e concentrações hormonais em touros Angus / Testicular development, spermatogenesis and hormonal concentrations in Angus bulls

    Scientific Electronic Library Online (English)

    Gyselle Viana, Aguiar; Airton Alencar, Araújo; Arlindo de Alencar Araripe, Moura.

    2006-08-01

    Full Text Available Este estudo foi realizado com a finalidade de avaliar a evolução das secreções hormonais e do epitélio seminífero em touros da raça Angus de 10 a 38 semanas de idade. Foram castrados 1 a 5 animais em intervalos de quatro semanas (total de 25 touros) para coleta de amostras do parênquima testicular e [...] do plasma sanguíneo. As variáveis relacionadas ao crescimento testicular, aos aspectos quantitativos da espermatogênese e aos níveis hormonais foram transformadas em logaritmo e avaliadas por meio de análise de variância. O diâmetro dos testículos e túbulos seminíferos e o peso testicular apresentaram variações mais acentuadas após 26 semanas de idade. A porcentagem do parênquima testicular ocupado pelos túbulos seminíferos aumentou de 49,3 para 75,2% durante o experimento. A maioria dos túbulos (>90%) apresentou-se com células de Sertoli somente entre 10 e 14 semanas, mas na 18ª (13,8±1,7%) e 22ª semanas (19±1%), o número de túbulos com gonócitos e espermatogônias aumentou em relação às semanas iniciais. Espermatogônias intermediárias e B predominaram na 26ª semana (24,5±8,2%) e a porcentagem de túbulos com espermatócitos foi mais elevada na 30ª semana (42,3±9,9%). Espermátides arredondadas foram detectadas partir da 26ª semana e, na 38ª semana, 62,3±1,5% dos túbulos seminíferos continham espermátides alongadas ou maduras. As variações mais acentuadas no crescimento testicular e, principalmente, no peso testicular após as 26 semanas coincidiram com o estabelecimento da meiose, com as alterações morfológicas do núcleo e nucléolo das células de Sertoli (indicativos do processo de diferenciação das mesmas), com os níveis reduzidos de androstenediona e os incrementos significativos de testosterona e estradiol 17beta. As associações entre o crescimento testicular e os níveis de FSH e LH na circulação periférica foram menos evidentes. Abstract in english This study aimed to evaluate changes in hormone secretion and in seminiferous epithelium of Angus bulls between 10 and 38 weeks of age. Samples of testicular parenchyma and blood were collected from 25 animals castrated in 4 week intervals. Traits associated to testicular development and quantitativ [...] e aspects of spermatogenesis and hormonal concentrations were transformed by logarithm before analyses of variance. Changes in testis and seminiferous tubule diameter and testis weight were more pronounced after 26 weeks of age. The percentage of testicular parenchyma occupied by seminiferous tubules increased from 49.3 to 75.2% from 10 to 38 weeks. Most tubules (>90%) had only Sertoli cells at 10 and 14 weeks, but the number of tubules with gonocytes and A spermatogonia increased at 18 (13.8±1.7%) and 22 weeks (19±1%). Tubules with B and intermediate spermatogonia became predominant at 26 weeks (24.5±8.2%) and those with spermatocytes as the most advanced germ cell type were more evident at 30 weeks (42.3±9.9%). Round spermatids were detected at 26 weeks and at 38 weeks of age, 62.3±1.5% of all tubules had either elongate or mature spermatids. Variations in testis growth (specially testis weight) after 26 weeks were coincident with the establishment of meiosis in the seminiferous tubules, morphological alterations in nucleus and nucleolus of the Sertoli cells (indicators of Sertoli cell differentiation), lower levels of androstenedione and significant increases in testosterone and estradiol 17beta. Associations between testis development and concentrations of FSH and LH were less evident.

  18. Quiste branquial tipo I: presentación de un caso / A type-I brachial cyst: a case report

    Scientific Electronic Library Online (English)

    Fidel, Castro Pérez; Raúl, Rodríguez González; Juan M, Flores Contreras; Vivian, Álvarez Díaz; María de las Nieves, Cordero Ledesma.

    2010-12-01

    Full Text Available Se presenta el caso de una adolescente de 14 años de edad, raza blanca, del sexo femenino, con antecedentes de salud relativa, que se valoró en la consulta externa del Policlínico Universitario Ernesto Guevara de la Serna de Sandino, Pinar del Río, Cuba. La paciente presentó un cuadro caracterizado [...] por el aumento de volumen superficial de la región lateral derecha superior del cuello, por debajo de la rama horizontal de la mandíbula y por delante del borde anterior del músculo esternocleidomastoideo, cerca del pabellón auricular y la parótida, de aproximadamente 4 cm. de diámetro, móvil, no doloroso, de superficie lisa y consistencia renitente, sin cambios en la coloración de la piel; al examen físico otorrinolaringológico no se encontraron otras alteraciones, posteriormente se realizó un ultrasonido en esa región. El diagnóstico dio como resultado un quiste branquial y se procedió a la exéresis quirúrgica por el equipo de autores del artículo, realizándose estudio anatomopatológico. Los autores presentan las experiencias derivadas de la atención del caso, y revisan la literatura médica sobre el tema con especial referencia al diagnóstico y tratamiento. Abstract in english A Caucasian 14 year-old female adolescent having relative health history was assessed at "Ernesto Guevara de la Serna" Outpatient Clinic in Sandino, Pinar del Rio, Cuba. The patient presented a clinical chart which was characterized by an increase of the superficial volume of the right upper lateral [...] region of neck, below the horizontal branch of the mandible and to the front of the anterior border of sternocleidomastoid muscle, near outer ear and parotid having approximately 4cm of diameter, motile, painless, smooth surface and renitent consistency, without changes in skin color; physical and ENT examinations found no other alterations, subsequently a sonographic study in that region confirmed a brachial cyst that was surgically removed performing pathological studies. The authors presented the experiences derived from this case and the medical literature about the topic was reviewed emphasizing on the diagnosis and treatment.

  19. Testicular torsion and weather conditions: analysis of 21,289 cases in Brazil

    Directory of Open Access Journals (Sweden)

    Fernando Korkes

    2012-04-01

    Full Text Available PURPOSE: The hypothesis of association between testicular torsion and hyperactive cremasteric reflex, worsened by cold weather, has not been proved. Thirteen studies in the literature evaluated this issue, with inconclusive results. The aim of the present study was to evaluate the seasonality of testicular torsion in a large subset of patients surgically treated in Brazil, and additionally to estimate the incidence of testicular torsion. MATERIALS AND METHODS: Brazilian Public Health System Database was assessed from 1992-2010 to evaluate hospital admissions associated with treatment of testicular torsion. Average monthly temperature between 1992-2010 was calculated for each region. RESULTS: We identified 21,289 hospital admissions for treatment of testicular torsion. There was a higher number of testicular torsions during colder months (p = 0.002. To estimate the incidence of testicular torsion, we have related our findings to data from the last Brazilian census (2010. In 2010, testicular torsion occurred in 1.4:100,000 men in Brazil. CONCLUSIONS:Testicular torsion occurred at an annual incidence of approximately 1.4:100,000 men in Brazil in 2010. Seasonal variations do occur, with a significant increase of events during winter. Our findings support the theory of etiological role of cold weather to the occurrence of testicular torsion. Strategies to prevent these events can be based on these findings.

  20. Taurine increases testicular function in aged rats by inhibiting oxidative stress and apoptosis.

    Science.gov (United States)

    Yang, Jiancheng; Zong, Xiaomeng; Wu, Gaofeng; Lin, Shumei; Feng, Ying; Hu, Jianmin

    2015-08-01

    In males, the decline of androgen synthesis, spermatogenesis and sexual function are the main phenotypes of aging, which may be attributed to testicular dysfunction. Taurine can act as an antioxidant, a testosterone secretion stimulator, a sperm membrane stabilizer and motility factor, and an anti-apoptotic agent. Recent observational studies suggested that taurine may play an important role in spermatogenesis, but to date whether taurine has anti-aging effects on testes remains unknown. We found that in aged rats testicular SDH and G6PDH activities, marker enzymes of testes, serum testosterone, testicular 3?-HSD and 17?-HSD mRNA expression levels were significantly increased by taurine treatment. Taurine administration also markedly raised the sperm count, viability and motility, decreased the sperm abnormality. Our data suggested that taurine can postpone testicular function deterioration in aged rats. Importantly, we observed obvious elevation of testicular antioxidant enzymes (SOD, GSH, GSH-Px) activities, and remarkable reduction of ROS and MDA by taurine administration, indicating taurine can decrease testicular oxidative stress and lipid peroxidation in aged rats. Finally, we found taurine effectively reduced testicular DNA fragmentation, increased testicular Bcl-2 protein expression, and decreased cytochrome c, Bax, Fas, FasL and caspase-3 expression, suggesting taurine can prohibit aged testicular apoptosis by mitochondrial dependent and independent signal pathway. In summary, our results indicated that taurine can suppress testicular function deterioration by increasing antioxidant ability and inhibiting apoptosis. PMID:25957528

  1. Fisetin inhibits growth, induces G2/M arrest and apoptosis of human epidermoid carcinoma A431 cells: Role of mitochondrial membrane potential disruption and consequent caspases activation

    OpenAIRE

    Pal, Harish C.; Sharma, Samriti; Elmets, Craig A; Athar, Mohammad; Afaq, Farrukh

    2013-01-01

    Non-melanoma skin cancers (NMSCs) one of the most common neoplasms causes serious morbidity and mortality. Therefore, identification of non-toxic phytochemicals for prevention/treatment of NMSCs is highly desirable. Fisetin (3,3?,4?,7-tetrahydroxyflavone), a dietary flavonoid, present in fruits and vegetables possesses anti-oxidant and anti-proliferative properties. The aim of this study was to investigate the chemotherapeutic potential of fisetin in cultured human epidermoid carcinoma A431 c...

  2. Carcinoma Epidermoide Primario de la Mama: Una Infrecuente Entidad Clínico-Patológica Primary Squamous Cell Carcinoma of the Breast: A Rare Clinicopathological Entity

    OpenAIRE

    Oscar Tapia E

    2011-01-01

    El carcinoma epidermoide (CE) puro primario de la mama es una rara entidad clínico-patológica, que representa menos del 0,1% de todos los carcinomas de mama, conformada en su totalidad por células escamosas malignas que no presentan relación anatómica con la piel adyacente de la mama. Su etiopatogenia, pronóstico y tratamiento son motivo de controversias. Presentamos 1 caso de CE puros primario de la mama diagnosticado en la Unidad de Anatomía Patológica del Hospital Hernán Henríquez Aravena ...

  3. Novel Tc-99m labeled ELR-containing 6-mer peptides for tumor imaging in epidermoid carcinoma xenografts model. A pilot study

    International Nuclear Information System (INIS)

    ELR-containing peptides targeting CXCR2 could be the excellent candidate for targeting ligand of molecular tumor imaging. In this study, we had developed two ELR-containing 6-mer peptides and evaluated the diagnostic performance of Tc-99m labeled 6-mer peptides as a molecular imaging agent in murine models bearing KB epidermoid carcinoma. Peptides were synthesized using Fmoc solid phase peptide synthesis. Radiolabeling efficiency with Tc-99m was evaluated using instant thin-layer chromatography. In KB epidermoid cancer-bearing mice, gamma images had acquired and tumor-to-muscle uptake ratio was calculated. Competition and biodistribution studies had performed. Two 6-mer peptides, ELR-ECG and ECG-ELR were successfully synthesized. After radiolabeling procedures with Tc-99m, the complex Tc-99m ELR-ECG and Tc-99m ECG-ELR were prepared in high yield. In the gamma camera imaging of murine model, Tc-99m ELR-ECG was substantially accumulated in the subcutaneously engrafted tumor and tumor uptake had been suppressed by the free ELR co-injection. However, Tc-99m ECG-ELR was minimally accumulated in the tumor. Two ELR-containing 6-mer peptides, ELR-ECG and ECG-ELR, were developed as a molecular imaging agent to target CXCR2 of epidermoid carcinoma. Tc-99m ELR-ECG had showed significant uptake in tumor and it was good candidate for a tumor imaging. (author)

  4. Detecção do rearranjo da proteína BCL2/JH em carcinomas epidermoides de boca e faringe / Detection of protein BCL2/JH rearrangement in epidermoid carcinomas of mouth and pharynx

    Scientific Electronic Library Online (English)

    Jair, Montovani; Magaly M, Sales; Maria Inês M C, Pardini.

    2010-09-01

    Full Text Available INTRODUÇÃO: A proteína BCL2 encontrada na membrana mitocondrial interna, regula a apoptose inibindo a morte celular programada. A translocação (14;18), detectada em 70 a 85% dos linfomas foliculares, leva a superexpressão da proteína BCL2, pela justaposição do gene BCL2 ao segmento JH do gene da cad [...] eia pesada da imunoglobulina. Porém, os achados da expressão da BCL2 em carcinoma de cabeça e pescoço são contraditórios. OBJETIVO: Investigar a presença da translocação (14;18) do gene BCL2 em carcinomas de cabeça e pescoço. MÉTODO: Foram examinadas 16 amostras de DNA, sendo 13 de carcinomas de células escamosas (CCE) e 3 de epidermoide (CE), por meio da reação em cadeia da polimerase (PCR). RESULTADOS: O rearranjo BCL2/JH foi encontrado em 2 (15%) dos 13 casos de CCE e em nenhum dos 3 casos de CE. A média de frequência de moléculas com rearranjo foi de 46,44 x 107. Não foi observada associação entre a presença de rearranjo e a exposição ao tabaco e álcool (p=0,6545). CONCLUSÃO: Diferente dos resultados encontrados em linfomas foliculares a presença da translocação (14;18) em carcinomas de cabeça e pescoço não é comum e, quando ocorre, pode ser uma mutação ocasional não associada a exposição ao tabaco e álcool. Abstract in english INTRODUCTION: The BCL2 protein found in the internal mothocondrial membrana regulates the apoptosis preventing the programmed cell death. The translocation (14:18), detected in 70 to 85% of the follicular lymphoma, lead the super expression of BCL2 protein, by juxtaposition of BCL2 gene to the JH se [...] gment of the immunoglobulins' heavy chain gene. However, the found of the BCL2 expression in head and neck carcinoma are contradictious. OBJECTIVE: To investigate the presence of the translocation (14:18) of the BCL2 gene in head and neck carcinoma. METHOD: Sixteen DNA samplers were examinated being 13 of squamous cells carcinoma (SCC) and 3 of epidermoid (CE), y means of chain reaction of the polymerase (PCR). RESULTS: The BCL2/JH rearrangement in 2 (15%) of the CCE 13 cases and in none of the 3 cases of CE. The average of the frequency of molecules with rearrangement was 46,44x107. Was not observed association between the rearrangement presence and the exhibition to tobacco and alcohol (p=0, 6545). CONCLUSION: Different from the results found in follicular lymphoma, the presence of the translocation (14; 18) in head and neck carcinomas is not common and, when it occurs, it can be an occasional mutation not associated to exhibition to the tobacco and alcohol.

  5. Immunohistochemistry Analysis of Proteins Related with Apoptosis as Prognostic Factor inEpidermoid Carcinomaof Penis / Análisis Inmunohistoquímico de Proteínas Relacionadas con la Apoptosis como Factor Pronóstico en el Carcinoma Epidermoide de Pene

    Scientific Electronic Library Online (English)

    P. C, Novais; A. A. P, de Paula; R. B, Reis; D. F, Barione; A. G, Franqueiro; A. A, Rodrigues Jr; F. S. N, Lizarte; C. A. M, de Carvalho; D. P. C, Tirapelli; F. M, Peria; F. P, Saggioro; S, Tucci Jr; A. J, Cologna; A. C. P, Martins; L. F, Tirapelli.

    2012-09-01

    Full Text Available El objetivo fue analizar la expresión de las proteínas de genes de apoptosis caspasa-3, caspasa-8 y Bcl-2-con la técnica de inmunohistoquímica, en correlación con el grado tumoral (I, II y III) y la supervivencia del paciente con el fin de comprender el mecanismo básico de la transformación tumoral. [...] Se analizaron las reacciones inmunohistoquímicas sobre 50 muestras de carcinoma de células escamosas mediante el método de la inmunoperoxidasa avidina-biotina y la recuperación de antígeno. Los análisis se realizaron utilizando el método de graduación "en cruces" (0 a 4 cruces - no tinción a más del 75% de las células positivas) y en categorías (baja, media, alta) de la inmunorreactividad citoplasmática de las células de carcinoma epidermoide de pene. Se observó una diferencia estadísticamente significativa cuando la expresión de la caspasa-3 se comparó con los grados I y II del tumor (p = 0,0010) y cuando se comparan la supervivencia de los pacientes con los grados I y II del tumor (p = 0,0212). La proteína bcl-2 se expresa más que la caspasa-3 y caspasa-8, lo que sugiere que la tasa de apoptosis en este carcinoma es baja. La mayor expresión de la proteína anti-apoptótica bcl-2 sugiere una mayor preservación de las células tumorales. Abstract in english The aim was to analyze the protein expression of apoptotic genes caspase-3, caspase-8 and bcl-2 with the immunohistochemistry technique, correlating with tumor grade (I, II and III) and with the patient survival in order to understand the basic mechanism of tumoral transformation. The immunohistoche [...] mistry reactions on 50 samples of squamous cell carcinoma were carried out with the avidin-biotin immunoperoxidase method and antigen recovery. The analyses were made using the graduation method "in crosses" (0 to 4 crosses - no stain to more than 75% of positives cells) and in categories (low, intermediate, high) of the cytoplasm immunoreactivity of the epidermoid penile carcinoma cells. It was observed a statistically significant difference when the expression of caspase-3 were compared with the grades I and II of the tumor (p=0.0010) and when comparing the patient survival with the grades I and II of the tumor (p=0.0212). The protein bcl-2 was more expressed than caspase-3 and caspase-8 proteins, suggesting that the apoptotic rate in this carcinoma is low. The higher expression of the anti-apoptotic protein bcl-2 suggests a higher preservation of the tumoral cells.

  6. Quiste conjuntival de inclusión tras cirugía de estrabismo según técnica de retroinserción en asa / Conjunctival inclusion cyst after strabismus surgery by hang-back recession

    Scientific Electronic Library Online (English)

    M.I., Pérez-Flores; J.A., Ortiz-Rey; I., Antón-Badiola; J., Lorenzo-Carrero.

    2006-11-01

    Full Text Available Caso clínico: Mujer de 24 años con antecedentes de endotropía congénita más DVD operada en la infancia. Se realiza intervención quirúrgica y cuatro meses tras la cirugía presenta una lesión quística que recidiva tras drenaje y tratamiento médico. Se realiza exéresis completa de la lesión. Discusión: [...] El origen de los quistes de inclusión conjuntivales tras cirugía de estrabismo sería la implantación escleral de células epiteliales. Sugerimos la relación con la sutura escleral como mecanismo de formación, independientemente de la posición del músculo. El tratamiento de elección en los quistes de gran tamaño es la resección completa. Abstract in english Case report: A 24-year-old woman, with a history of infantile esotropia and DVD operated on in infancy, had strabismus surgery performed by us. Four months later she presented with a cystic lesion that recurred after drainage and medical treatment. Complete excision of the cystic lesion was therefor [...] e performed. Discussion: The epithelial cells implanted on the sclera at the time of the most recent surgery may have been the origin of inclusion cyst which developed after the strabismus surgery. This suggests a possible relationship with the scleral suture as the mechanism of cyst formation, independent of the muscle position. Complete excision is the recommended treatment for large cysts.

  7. Effect of 5-alpha-reductase inhibitor, 4-MAPC, on testicular descent in male rat.

    Science.gov (United States)

    Ngyuen, M M; Lemmi, C A; Rajfer, J

    1991-05-01

    Testicular descent has been reported to be a dihydrotestosterone (DHT) dependent event. To further elucidate the role of DHT in the process of testicular descent, a group of rats were treated with the 5-alpha reductase inhibitor, 4-MAPC, from birth to day 28 of age and the incidence of testicular descent as well as ventral prostate weight was noted at day 29 of age. It was determined that in the doses used, 4-MAPC failed to prevent testicular descent. Because 4-MAPC inhibited ventral prostate weight by only 53% (as compared to a 75% inhibition by castration), the failure of the 4-MAPC to prevent testicular descent could be due to its inability to completely inhibit tissue 5-alpha reductase activity. The results of this study do not mitigate against the role of other nonhormonal factors working in tandem with DHT in the induction of testicular descent in this animal model. PMID:2016800

  8. Carcinoma epidermoide oral y orofaríngeo: Estudio clínico-patológico / Oral and oropharingeal squamous cells carcinoma: Clinico-pathological study

    Scientific Electronic Library Online (English)

    Pablo, Guzmán G; Miguel, Villaseca H; Lilia, Antonio P; Juan, Araya O; Paola, Aravena M; Carla, Cravero P; Pilar, Pino M; Juan, Roa S.

    2011-06-01

    Full Text Available Introducción: El cáncer oral es una enfermedad frecuente en muchas partes del mundo, en Chile corresponde al 1,6% del total de cánceres. La gran mayoría corresponde a carcinoma epidermoide, con importantes diferencias clínicas, epidemiológicas y patológicas entre las localizaciones labial, intraoral [...] y orofaríngea. Objetivo: Analizar las características clínicas y patológicas del carcinoma epidermoide oral y orofaríngeo en Temuco, Chile. Material y Método: Estudio descriptivo, retrospectivo de todos los casos diagnosticados en 15 años (1994 y 2008), en el Hospital Regional de Temuco. Los pacientes fueron analizados de acuerdo a género, edad, y los tumores fueron clasificados basados en su localización anatómica, tamaño, características macroscópicas y grado de diferenciación. Resultados: Se encontraron 93 carcinomas, con relación hombre:mujer de 5:1, edad promedio 67 años. Pacientes menores a 50 años correspondían sólo al 8% de los casos. Las localizaciones más frecuentes fueron labio inferior, lengua y encía, con un tamaño promedio de 28 mm, el que aumentó hacia la orofarinx, más de la mitad eran moderadamente diferenciados. Conclusiones: En nuestra región, este carcinoma afecta con mayor frecuencia a la séptima década de la vida y a población masculina y posee características similares a las descritas en otros países donde predomina la raza blanca. El tamaño al diagnóstico es considerable. La detección de algunas diferencias en el grupo con apellidos mapuches amerita un estudio con un mayor número de casos. Abstract in english Introduction: Oral cancer is a common disease in many parts of the world, in Chile only accounts for 1.6% of all cancers. The majority is squamous cell carcinoma with important clinical, epidemiological and pathological differences between lip, oral and orofaringeal locations. Objective: To analyze [...] clinical and pathological characteristics of oral and oropharingeal squamous cell carcinoma in Temuco, Chile. Materials and Methods: A descriptive, retrospective study of all diagnosed cases in 15 years (1994 and 2008). The patients were analyzed according to gender, age; and the tumors were classified based on anatomic location, size, macroscopical findings and degree of differentiation. Results: We found 93 carcinomas, with male to female ratio of 5:1, average age 67 years. Patients under 50 years accounted for only 8% of cases. The most common sites were lower lip, tongue and gingiva, with an average size of 28 mm, which increased towards orofarinx and more than half were moderately differentiated. Conclusions: In our region, this carcinoma most often affects the seventh decade of life and male population and has similar characteristics to those in other countries which is predominantly. The size at diagnosis is significant. The detection of some differences in the group with mapuche surnames warrants a study with a larger number of cases.

  9. Quiste dentígero asociado con mesiodens: Exposición de un caso, revisión de la literatura y diagnóstico diferencial Dentigerous cyst associated with mesiodens: a case report, literature review and differential diagnostic

    Directory of Open Access Journals (Sweden)

    F.J. Rodríguez Romero

    2011-12-01

    Full Text Available El quiste dentígero es uno de los quistes odontogénicos más frecuentes y están asociados con la corona de un diente no erupcionado o en desarrollo. Cuando se asocian con dientes supernumerarios son poco frecuentes y constituyen el 5-6% de todos los quistes dentígeros. En región maxilar, el 90% de los casos se asocian a mesiodens. El objetivo de este artículo es exponer el caso de una adolescente de 14 años con un quiste dentígero asociado con un diente supernumerario (mesiodens impactado en región maxilar anterior, su manejo dental y revisión de la literatura.Dentigerous cyst is one of the most prevalent types of odontogenic cyst and is associated with crown of an unerupted or developing tooth. Dentigerous cysts associated with supernumerary teeth are rare and estimated to constitute 5-6% of all dentigerous cysts. The vast majority, about 90%, are associated with a maxillary mesiodens. The purpose of this article to report the case of an 14-year-old a teenager with a dentigerous cyst associated with an impacted anterior maxillary supernumerary tooth, its dental management and literature review.

  10. Quiste dentígero asociado con mesiodens: Exposición de un caso, revisión de la literatura y diagnóstico diferencial / Dentigerous cyst associated with mesiodens: a case report, literature review and differential diagnostic

    Scientific Electronic Library Online (English)

    F.J., Rodríguez Romero; S., Cerviño Ferradanes; P., Muriel Cueto.

    2011-12-01

    Full Text Available El quiste dentígero es uno de los quistes odontogénicos más frecuentes y están asociados con la corona de un diente no erupcionado o en desarrollo. Cuando se asocian con dientes supernumerarios son poco frecuentes y constituyen el 5-6% de todos los quistes dentígeros. En región maxilar, el 90% de lo [...] s casos se asocian a mesiodens. El objetivo de este artículo es exponer el caso de una adolescente de 14 años con un quiste dentígero asociado con un diente supernumerario (mesiodens) impactado en región maxilar anterior, su manejo dental y revisión de la literatura. Abstract in english Dentigerous cyst is one of the most prevalent types of odontogenic cyst and is associated with crown of an unerupted or developing tooth. Dentigerous cysts associated with supernumerary teeth are rare and estimated to constitute 5-6% of all dentigerous cysts. The vast majority, about 90%, are associ [...] ated with a maxillary mesiodens. The purpose of this article to report the case of an 14-year-old a teenager with a dentigerous cyst associated with an impacted anterior maxillary supernumerary tooth, its dental management and literature review.

  11. Enucleación de quiste periapical simultáneo a la obturación del sistema de conductos radiculares / Periapical cyst enucleation and simultaneous sealing of the root canal system

    Scientific Electronic Library Online (English)

    Lida, Velazque; Alexandre, Simões-Nogueira; Ilan, Sampaio do Vale; Victor, Tiegui Neto; Andrea, Guedes Barreto Gonçales; Eduardo, Sánches Gonçales.

    2014-06-01

    Full Text Available Introducción: los quistes periapicales representan el tipo más frecuente dentro de los quistes odontogénicos. Su origen está relacionado con una necrosis pulpar y un consecuente estímulo de los restos epiteliales del ligamento periodontal (Malassez). Objetivo: describir un caso clínico de enucleació [...] n de quiste periapical simultáneo a la obturación del sistema de conductos radiculares. Presentación del caso: paciente de sexo femenino, 67 años de edad, sin alteraciones sistémicas; buscó atención odontológica por presentar dolor dental y acúmulo de alimentos en la región de molares inferiores del lado izquierdo. Al examen clínico se observó caries extensa en el segundo molar inferior izquierdo con compromiso de furca, ausencia de aumento de volumen vestibular, sin fistula; en la radiografía periapical se evidenció lesión cariosa extensa recidivante en el segundo molar inferior izquierdo, y primer molar inferior izquierdo con tratamiento endodóntico y presencia de área radiolúcida de contornos bien definidos en la región periapical compatible con quiste periapical. El tratamiento estuvo a cargo de un equipo multidisciplinario por lo que se decidió realizar exodoncia del segundo molar inferior izquierdo y cirugía paraendodóntica con enucleación quirúrgica simultánea a la obturación del sistema de conductos radiculares primer molar inferior izquierdo; el examen histopatológico de la muestra extraída comprobó tratarse de un quiste periapical. Se realizó seguimiento radiográfico dos años después y mostró un completo reparo óseo del área afectada. Conclusiones: se concluye que el tratamiento descrito constituye una alternativa válida para la resolución de casos donde la endodoncia convencional es limitada para mantener la función y estética de una pieza dentaria. Abstract in english Introduction: periapical cysts are the most common odontogenic cysts. Their origin is related to pulp necrosis and the consequent stimulation of epithelial rests of the periodontal ligament (Malassez). Objective: describe a clinical case of periapical cyst enucleation and simultaneous sealing of the [...] root canal system. Case report: a female 67-year-old patient without any systemic alteration sought care for dental pain and accumulation of food in the area of the lower left molars. Clinical examination revealed extensive decay in the lower left second molar with furcation involvement and absence of vestibular volume increase without a fistula. Periapical radiography showed an extensive recurrent carious lesion in the lower left second molar and lower left first molar with endodontic treatment and presence of a radiolucent area of a sharp outline in the periapical region compatible with periapical cyst. Treatment was conducted by a multidisciplinary team, who decided to perform extraction of the lower left second molar and paraendodontic surgery with surgical enucleation and simultaneous sealing of the root canal system in the lower left first molar. Histopathological examination of the specimen removed revealed it was a periapical cyst. Radiographic follow-up conducted two years later showed complete bone repair in the affected area. Conclusions: it is concluded that the treatment described is a valid alternative for the resolution of cases in which conventional endodontics is insufficient to preserve the function and aesthetic appearance of a tooth.

  12. Testicular Involvement in Wegener Granulomatosis: Case Report and Review of the literature

    Directory of Open Access Journals (Sweden)

    Mehmet Nuri TURAN

    2012-05-01

    Full Text Available Wegener granulomatosis (WG is a type of necrotising vasculitis that affects mainly the respiratory tract, paranasal sinuses and the kidneys. Urogenital involvement is rare; mainly affecting the prostate gland. Testicular involvement in WG is exceptional. We report a 50-year-old male patient with hematuria, proteinuria and testicular pain and renal failure diagnosed as WG by testicular and kidney biopsy. We also provide a review of the literature.

  13. Spatial variation and temporal trends of testicular cancer in Great Britain

    OpenAIRE

    Toledano, M B; Jarup, L.; Best, N.; Wakefield, J.; ELLIOTT, P

    2001-01-01

    Increases in testicular cancer incidence have been reported in several countries over a long period. Geographical variability has also been reported in some studies. We have investigated temporal trends and spatial variation of testicular cancer at ages 20–49 in Britain. Temporal trends in testicular cancer incidence were examined, 1974 to 1991 and in mortality, 1981–1997. Spatial variation in incidence was analysed across electoral wards, 1975 to 1991. We used Poisson regression to examine f...

  14. Incidental Discovery of Testicular Microlithiasis: What Is the Importance of Ultrasound Surveillance? Two Case Reports

    OpenAIRE

    Barchetti, F.; Marco, V; Barchetti, G.; Pasqualitto, E.; A. Sartori; Glorioso, M.; Gigli, S.; V. Megna; Montechiarello, S.; Boncore, V.; STAGNITTI, A.

    2013-01-01

    Many studies have demonstrated an association between diffuse bilateral testicular microlithiasis (TM) and gonadal and extragonadal germ cell tumors. Nevertheless, it is still uncertain whether ultrasound surveillance is really necessary in patients with TM in the absence of other risk factors such as previous testicular cancer, a history of cryptorchidism or testicular atrophy. We report the cases of a 33- and a 39-year-old man presenting with a retroperitoneal extragonadal tumor. The first ...

  15. Birth order, sibship size, and risk for germ-cell testicular cancer

    OpenAIRE

    RICHIARDI, LORENZO

    2004-01-01

    BACKGROUND: Several studies have reported an inverse association between birth order and testicular cancer risk, but estimates vary greatly and the biologic mechanism underlying the association is not established. METHODS: We have evaluated the effect of birth order, sibship size, and the combined effect of these 2 variables in relation to risk for testicular cancer in a large, nested case-control study. Specifically, we compared 3051 patients with germ-cell testicular cancer (diagnosed betwe...

  16. Advanced and recurrent testicular rhabdomyosarcoma in a young adult: A rare case report

    Directory of Open Access Journals (Sweden)

    L Purnima Devi

    2015-01-01

    Full Text Available Rhabdomyosarcoma (RMS is one of the most frequent soft tissue sarcomas. Pure testicular RMS is a very rare tumor and a few cases have been reported in the literature. We report a 16-year-old male patient with a painless right testicular swelling who underwent high inguinal orchiectomy and diagnosed as testicular embryonal RMS. The patient had a rare recurrence at the scrotal site with inguinal and retroperitoneal metastasis.

  17. Effects of testicular microlithiasis on Doppler parameters: report of three cases

    OpenAIRE

    Alkan Alpay; Baysal Tamer; Sigirci Ahmet; Kutlu Ramazan; Sarac Kaya

    2002-01-01

    Abstract Background Testicular microlithiasis is a rare, usually asymptomatic, non-progressive disease of the testes associated with various genetic anomalies, infertility and testicular tumors. According to our literature search, there is no specific data about Doppler findings in this disease. Case presentation Doppler findings of three cases of testicular microlithiasis during last two years in our institution are presented. Conclusions Although our hypothesis was to find increased Doppler...

  18. Testicular Infarction and Rupture After Blunt Trauma — Use of Diagnostic Ultrasound

    OpenAIRE

    Alistair Pace; Christopher Powell

    2004-01-01

    We report the case of a 23-year-old male who suffered localised testicular infarction and rupture following blunt trauma. This pathology is rare after blunt trauma and has not been previously described in literature. The appearance on ultrasound resembled malignancy, necessitating orchidectomy. An overview of the pathology of testicular trauma as well as its management is given with particular emphasis on the use diagnostic ultrasound in testicular trauma.

  19. Inhibitory effect of chondroitin sulfate oligosaccharides on bovine testicular hyaluronidase.

    Science.gov (United States)

    Kakizaki, Ikuko; Koizumi, Hideyo; Chen, Fengchao; Endo, Masahiko

    2015-05-01

    Hyaluronan and chondroitin sulfates are prominent components of the extracellular matrices of animal tissues; however, their functions in relation to their oligosaccharide structures have not yet been fully elucidated. The oligosaccharides of hyaluronan and chondroitin sulfate were prepared and used to investigate their effects on the hydrolysis and transglycosylation reactions of bovine testicular hyaluronidase when hyaluronan was used as a substrate. Hydrolysis and transglycosylation activities were assessed in independent reaction systems by analyzing the products by HPLC. The hydrolysis and transglycosylation reactions of bovine testicular hyaluronidase were dose-dependently inhibited by chondroitin sulfate oligosaccharides, but not by hyaluronan or chondroitin oligosaccharides. A kinetic analysis of the hydrolysis reaction using hyaluronan octasaccharide revealed that the inhibition mode by chondroitin sulfate oligosaccharides was competitive. PMID:25659711

  20. Testicular dysgenesis syndrome: foetal origin of adult reproductive problems

    DEFF Research Database (Denmark)

    Wohlfahrt-Veje, Christine; Main, Katharina M; Skakkebaek, Niels Erik

    2009-01-01

    The evidence for the existence of testicular dysgenesis syndrome (TDS) is presented in this review. Several epidemiological studies have shown that conditions like cryptorchidism, impaired spermatogenesis, hypospadias and testicular cancer can be associated as risk factors for each other. Thus, the...... risk of testis cancer is significantly increased in men with cryptorchidism and/or infertility. Several recent studies point towards early dysgenesis of the foetal testis as the biological link between these disorders. Dysgenesis has been demonstrated in biopsies of the contralateral testis of men with...... testis cancer and in infertile men. The histological evidence includes immature seminiferous tubules with undifferentiated Sertoli cells, microliths and Sertoli-cell only tubules. Dysgenetic testes often have an irregular ultrasound pattern, where microliths may also be visible. Our current hypothesis is...

  1. Testicular germ cell tumors: Molecular genetic and clinicomorphological aspects

    Directory of Open Access Journals (Sweden)

    M. V. Nemtsova

    2015-03-01

    Full Text Available Testicular tumors are the most common form of solid cancer in young men. According to the 2004 WHO classification, testicular germ cell tumors (TGCT may present with different histological types. Embryonic cells of varying grade may be a source of TGCT and the occurrence of this type of tumors is directly related to the formation of a pool of male sex cells and gametogenesis. The paper gives information on mo- lecular stages for the process of formation of male sex cells in health, as well as ways of their impairments leading to TGCT. An investigation of the profiles of gene expression and the spectrum of molecular damages revealed genes responsible for a predisposition to the sporadic and hereditary forms of TGCT. The paper presents the current molecular genetic and clinicomorphological characteristics of TGCT. 

  2. Gynecomastia caused by testicular irradiation. A case report

    International Nuclear Information System (INIS)

    Gynecomastia in a 20-years-old male is reported. At the age of 2, the patients had contracted acute lymphocytic leukemia (ALL), at which time irradiation for the testicular ALL invasion was performed. This irradiation induced atrophy of the testis. Obesity was first noted when he was 12 years old, after which enlargement of the bilateral breasts occurred at 14 years of age. When he turned 19, supplementary testosterone therapy was initiated to counter the gynecomastia, but it proved ineffective. Thus, a total mastectomy was performed with free nipple grafting. Pathologically, inspected mammary tissue specimens revealed mammary ducts in a fibrous stroma that had encompassed lobules of adipose tissue. The findings in this case suggest that the testicular irradiation had induced primary hypogonadism and that this had resulted in gynecomastia and obesity. (author)

  3. Phthalate-induced testicular dysgenesis syndrome: Leydig cell influence.

    Science.gov (United States)

    Hu, Guo-Xin; Lian, Qing-Quan; Ge, Ren-Shan; Hardy, Dianne O; Li, Xiao-Kun

    2009-04-01

    Phthalates, the most abundantly produced plasticizers, leach out from polyvinyl chloride plastics and disrupt androgen action. Male rats that are exposed to phthalates in utero develop symptoms characteristic of the human condition referred to as testicular dysgenesis syndrome (TDS). Environmental influences have been suspected to contribute to the increasing incidence of TDS in humans (i.e. cryptorchidism and hypospadias in newborn boys and testicular cancer and reduced sperm quality in adult males). In this review, we discuss the recent findings that prenatal exposure to phthalates affects Leydig cell function in the postnatal testis. This review also focuses on the recent progress in our understanding of how Leydig cell factors contribute to phthalate-mediated TDS. PMID:19278865

  4. CANCER TESTICULAR: ESTUDIO DE EXTENSION CON TC DE CUERPO ENTERO

    Directory of Open Access Journals (Sweden)

    Jaime Schwaner C

    2005-01-01

    Full Text Available Introducción. La evaluación con tomografía computada (TC de tórax, abdomen y pelvis de pacientes con cáncer testicular es importante para determinar la extensión de su enfermedad y los controles post-tratamiento. Quienes presentan metástasis son candidatos a quimioterapia lo que permite una supervivencia mayor al 80% en el largo plazo. Objetivos: Estimar la frecuencia de invasión regional y a distancia usando TC de cuerpo entero en los diferentes tipos histológicos de cáncer testicular y correlacionar con las pautas de pronóstico del Consenso Europeo para el diagnóstico y tratamiento de este tipo de cáncer. Material y método: Nuestro estudio incluyó 85 pacientes con cáncer testicular diagnosticados por clínica y estudio ecotomográfico en el Hospital Regional de Concepción entre los años 2002 a 2005. A todos ellos se les realizó TC tórax-abdomen-pelvis para estadificación. Los estudios fueron realizados con escáner helicoidal usando en forma rutinaria contraste oral y endovenoso no iónico en dosis estándar de 150 ml. Las imágenes axiales y reconstruidas fueron analizadas por radiólogos del servicio de imagenología. Se consigno la presencia, y ubicación de linfonódulos metastásicos y metástasis. El estudio histológico del tumor testicular se relacionó con su estadificación según la TC de cuerpo entero, siendo luego agrupados en grupos pronósticos para estimar probabilidad de sobrevida. Resultados: En nuestra casuística, los tumores testiculares afectan a varones con un promedio de edad de 31 años y en un rango de 19 a 57 años. Según TNM (AJCC staging system 1997: en etapa I estaban 43 pacientes (50,6%, en etapa II 20 (23,5% y en etapa III 22 (25,9%. En 43 pacientes el tipo histológico fue seminoma clásico puro y en 42 no-seminoma. De los 42 pacientes con tumores no seminomas: cinco presentaron carcinoma em-brionario puro y 20 mixto, coriocarcinoma mixto se observo en seis, teratoma maduro en siete y en un paciente teratoma inmaduro. Sólo tres casos presentaron teratocarcinomas. Conclusión: La proporción de seminomas y no seminomas se correlaciona con la literatura nacional e internacional, excepto con un estudio del grupo español. Nuestros grupos pronósticos difieren con los del Consenso Europeo para el diagnóstico y tratamiento del tumor testicular. Pensamos que la Rx de tórax se podría obviar en la evaluación inicial y usar solamente TC de tórax, abdomen y pelvis en los centros que cuenten con tecnología helicoidal, ya que de esta forma evitamos una reevaluación en los casos de radiografía sospechosa o con signos de diseminación secundaria, usando una sola inyección de contraste, apnea y tiempo de examen.Today testicular cancer has good treatment and long-term survival. Thorax, abdomen and pelvis computerized tomography especially helical technique is the most important tool to evaluate dissemination. We analyzed retrospectively 85 patients studied in the Hospital Regional de Concepción between 2002-2005 with testicular tumors whom had complete laboratory and TC helical evaluation and correlated local invasion detected in surgery with CT staging for estimate prognostic survival in agree with European consensus on diagnosis and treatment of germ cell cancer. The mean age at the time of diagnosis was 31 years (Range 19-57. Forty three were seminoma and 42 non seminomatous tumors. Staging demonstrated 43 stage I, 20 stage II and 22 stage III. Our prognostic groups were different to other series with 71% of patient's good prognostic, 24% intermediate and only 5% bad prognostic (non seminomatous tumors. We think that the new technology helical can obviate chest x-ray in the initial evaluation of these patients

  5. Testicular Feminization: Report of Three Cases in a Family

    Directory of Open Access Journals (Sweden)

    H Moayyeri

    2002-10-01

    Full Text Available Case of the complete syndrome of testicular feminization were reported early in the 19th century, but it was in 1950 that Lawson recognized the etiology in a patient with amenorrhea and failing pubic and axillary hair, which was unresponsive to testosterone therapy. The prevalence of androgen resistance is estimated to be between 1:20.000 and 1:64.000 men and the complete form is the 3rd most common cause of primary amenorrhea. Testicular feminization is transmitted as X-linked recessive trait. In this article, we report on three siblings in a family with complete form of androgen insensitivity. The first case, the youngest of the siblings, was recognized by an inguinal hernia operation. The diagnosis was established chromosomal analysis, hormonal assays, sonography, and pathological examination after laparotomy.

  6. The role of radioimmunodetection in the management of testicular cancer

    Energy Technology Data Exchange (ETDEWEB)

    Javadpour, N.; Kim, E.E.; DeLand, F.H.; Salyer, J.R.; Shah, U.; Goldenberg, D.M.

    1981-07-03

    Five patients with testicular cancer received an intravenous injection of between 1 and 2.5 mCi of iodine 131-labeled antibody to human chorionic gonadotropin (HCG) or alpha-fetoprotein (AFP), followed by total-body photoscanning to visualize areas of abnormal radioactivity. Blood-pool and nontarget sites of radioactivity were reduced by subtracting the images derived by injection of technetium Tc 99m-labeled components from the iodine 131 scans. The HCG-immune scintiscans proved helpful in tumor localization and in the selection of appropriate therapy, while the AFP scan presented corroborative evidence of widespread tumor. Elevated serum levels of these two markers did not hinder successful tumor detection and localization by this method of radioimmunodetection. Cancer radioimmunodetection with antibodies to HCG and to AFP appears to be a useful procedure for the pretreatment and posttreatment evaluation of patients with testicular cancer and can reveal sites of tumor not detected by other methods.

  7. Gynecomastia caused by testicular irradiation. A case report

    Energy Technology Data Exchange (ETDEWEB)

    Mori, Hiroki; Umeda, Tadashi; Katayama, Ichiro; Nishioka, Kiyoshi [Tokyo Medical and Dental Univ. (Japan). School of Medicine

    1996-09-01

    Gynecomastia in a 20-years-old male is reported. At the age of 2, the patients had contracted acute lymphocytic leukemia (ALL), at which time irradiation for the testicular ALL invasion was performed. This irradiation induced atrophy of the testis. Obesity was first noted when he was 12 years old, after which enlargement of the bilateral breasts occurred at 14 years of age. When he turned 19, supplementary testosterone therapy was initiated to counter the gynecomastia, but it proved ineffective. Thus, a total mastectomy was performed with free nipple grafting. Pathologically, inspected mammary tissue specimens revealed mammary ducts in a fibrous stroma that had encompassed lobules of adipose tissue. The findings in this case suggest that the testicular irradiation had induced primary hypogonadism and that this had resulted in gynecomastia and obesity. (author)

  8. Painless inter epididymal testicular torsion of the spermatic cord

    Directory of Open Access Journals (Sweden)

    Salomon V. Romano

    2007-02-01

    Full Text Available Inter epididymal testicular torsion of the spermatic cord is extremely rare and usually diagnosed at surgery. We present an unusual case of spermatic cord torsion in a 14-year-old male patient. It is important to highlight that the torsion occurred only on the distal half of the epididymis leaving the head untwisted and edematous. In addition, the fact that this condition was painless made this case extremely rare and motivated our presentation.

  9. Medical image of the week: metastatic testicular cancer

    OpenAIRE

    Debo M; Snyder L; Rhodes SM

    2014-01-01

    A 30 year-old man with metastatic embryonal testicular cancer was admitted to the hospital with severe abdominal pain. A contrast enhanced CT of the abdomen demonstrated large metastatic burden throughout the liver and the left adrenal gland (Figures 1 and 2). The mass arising from the left adrenal gland caused significant mass effect. The left kidney was compressed, though without hydronephrosis, and the spleen was displaced laterally. Renal and hepatic functions were preserved. His pain was...

  10. Human testicular peritubular cells: more than meets the eye.

    Science.gov (United States)

    Mayerhofer, Artur

    2013-05-01

    In healthy men, several layers of inconspicuously flat cells and extracellular matrix (ECM) proteins build the wall of the seminiferous tubules. The cells of this wall, peritubular cells, are not well characterized. They are smooth-muscle-like and contractile and transport immotile sperm, a function important for male fertility. However, their full functional importance, especially their potential contribution to the paracrine regulation of the male gonad, is unknown. In men with impaired spermatogenesis, the architecture of the tubular wall is frequently altered. Deposits of ECM and morphological changes of peritubular cells imply that functions of peritubular cells may be fundamentally altered. To be able to study human peritubular cells and their functions, a culture method was established. It is based on small biopsies of patients with obstructive azoospermia but normal spermatogenesis (human testicular peritubular cells, HTPCs) and non-obstructive azoospermia, impaired spermatogenesis, and testicular fibrosis (HTPCFs). Results obtained from cellular studies and parallel examinations of biopsies provide insights into the repertoire of the secretion products, contractile properties, and plasticity of human peritubular cells. They produce ECM components, including the proteoglycan decorin, which may influence paracrine signaling between testicular cells. They may contribute to the spermatogonial stem cell niche via secreted factors. They are regulated by mast cell and macrophage products, and in response produce factors that can fuel inflammatory changes. They possess a high degree of plasticity, which results in hypertrophy and loss of contractile abilities. The data collectively indicate important roles of inconspicuous testicular peritubular cells in human male fertility and infertility. PMID:23431272

  11. Ochratoxin A is not detectable in renal and testicular tumours

    Science.gov (United States)

    Fahmy, Nader; Woo, Mark; Alameldin, Mona; MacDonald, Kyle; Goneau, Lee W.; Cadieux, Peter; Pautler, Stephen E.

    2014-01-01

    Introduction: Ochratoxin-A (OTA) is one of the most abundant food-contaminating mycotoxins, known for its nephrotoxicity, neurotoxicity, gonadotoxicity, teratogenicity, immunosuppression and carcinogenesis. OTA has been linked to several genitourinary pathologies, including Balkan nephropathy and genitourinary malignancies. We examine OTA levels in serum samples and tumour specimens collected from patients with renal and testicular tumours. Methods: Frozen samples were obtained from the Ontario Tumour Bank. Serum specimens, along with renal and testicular tumour biopsies, were included in this study. Normal tissue from the negative surgical margins of each tumour served as a control. OTA levels in serum was measured using the enzyme-linked immunosorbent assay (ELISA), while OTA detection in tissue specimens was determined using immunohistochemistry (IHC). Results: We included specimens collected from 56 patients (36 men and 20 women). Histopathology of the 52 renal tumours included 31 (60%) conventional type renal cell carcinomas (RCC), 5 (10%) chromophobe RCC, 5 (10%) papillary RCC, 1 (2%) oncocytoma and 10 (19%) upper tract urothelial carcinoma (UC). The 4 testicular tumours included 1 seminomatous (25%) germ cell tumour and 3 (75%) non-seminomatous germ cell tumours. OTA was detected in the serum of renal tumour patients, with a range from 0.004 to 0.25 ng/mL (mean: 0.07 and median 0.06 ng/mL). There was no OTA signal detected by IHC staining in all tested renal and testicular tumours. Conclusions: The OTA levels detected in the serum of patients were highly variable and relatively low. No OTA was detected in the tissue samples. PMID:24578744

  12. Adolescent and adult risk factors for testicular cancer

    OpenAIRE

    McGlynn, Katherine A; Trabert, Britton

    2012-01-01

    The incidence of testicular cancer has been increasing over the past several decades in many developed countries. The reasons for the increases are unknown because risk factors for the disease are poorly understood. Some research suggests that exposures in utero or in early childhood are likely to be important in determining an individual's level of risk. However, other research suggests that exposure to various factors in adolecence and adulthood are also linked to the development of testicu...

  13. Dietary Cholesterol-Induced Post-Testicular Infertility

    OpenAIRE

    Ouvrier, Aurélia; Alves, Georges; Damon-Soubeyrand, Christelle; Marceau, Geoffroy; Cadet, Rémi; Janny, Laurent; Brugnon, Florence; Kocer, Ayhan; Pommier, Aurélien; Lobaccaro, Jean-Marc A; Drevet, Joël R.; Saez, Fabrice

    2011-01-01

    This work shows that an overload of dietary cholesterol causes complete infertility in dyslipidemic male mice (the Liver X Receptor-deficient mouse model). Infertility resulted from post-testicular defects affecting the fertilizing potential of spermatozoa. Spermatozoa of cholesterol-fed lxr?/? animals were found to be dramatically less viable and motile, and highly susceptible to undergo a premature acrosome reaction. We also provide evidence, that this lipid-induced infertility is associate...

  14. A survey of etiologic hypotheses among testicular cancer researchers

    DEFF Research Database (Denmark)

    Stang, A; Trabert, B

    2015-01-01

    Basic research results can provide new ideas and hypotheses to be examined in epidemiological studies. We conducted a survey among testicular cancer researchers on hypotheses concerning the etiology of this malignancy. All researchers on the mailing list of Copenhagen Testis Cancer Workshops and corresponding authors of PubMed-indexed articles identified by the search term 'testicular cancer' and published within 10 years (in total 2750 recipients) were invited to respond to an e-mail-based survey. Participants of the 8th Copenhagen Testis Cancer Workshop in May 2014 were subsequently asked to rate the plausibility of the suggested etiologic hypotheses on a scale of 1 (very implausible) to 10 (very plausible). This report describes the methodology of the survey, the score distributions by individual hypotheses, hypothesis group, and the participants' major research fields, and discuss the hypotheses that scored as most plausible. We also present plans for improving the survey that may be repeated at a next international meeting of experts in testicular cancer. Overall 52 of 99 (53%) registered participants of the 8th Copenhagen Testis Cancer Workshop submitted the plausibility rating form. Fourteen of 27 hypotheses were related to exposures during pregnancy. Hypotheses with the highest mean plausibility ratings were either related to pre-natal exposures or exposures that might have an effect during pregnancy and in post-natal life. The results of the survey may be helpful for triggering more specific etiologic hypotheses that include factors related to endocrine disruption, DNA damage, inflammation, and nutrition during pregnancy. The survey results may stimulate a multidisciplinary discussion about new etiologic hypotheses of testicular cancer.

  15. ER? and ER? in mouse testicular cells and sperm.

    Czech Academy of Sciences Publication Activity Database

    Dostálová, Pavla; D?d, Lukáš; P?knicová, Jana

    Praha : Biotechnologický ústav, 2013 - (P?knicová, J.). s. 22-23 [XIX. Symposium imunologie a biologie reprodukce s mezinárodní ú?astí. 23.05.2013-25.05.2013, T?eš?] R&D Projects: GA ?R(CZ) GAP503/12/1834 Institutional research plan: CEZ:AV0Z50520701 Keywords : Estrogen receptor ? ? * Estrogen receptor ? * Testicular cells * Sperm atogenesis Subject RIV: EB - Genetics ; Molecular Biology

  16. Endocrinological aspects in the therapy of testicular affections in children suffering from acute leukemias

    International Nuclear Information System (INIS)

    Orchidectomy or testicular irradiation with 24 to 30 Gy are recommended for testicular involvement in boys with acute lymphoblastic leukemia. But, recommended radiation doses for the only occulty involved other testis differ, i.e. they range from 12 to 24 Gy. Low dose (12 or 15 Gy) 'preventive' testicular irradiation was delivered to 5 of 14 patients; only one of these 5 experienced a further testicular relapse. According to our observation, in contrast to higher doses, the dose limitation allows spontaneous pubertal development including normal testosteron production and normal development of the masculine stature. (author)

  17. Scintigraphy and color duplex doppler sonography to detect testicular vascular disturbances in varicocele

    International Nuclear Information System (INIS)

    The detection of a varicocele represent an important part of the infertility workup because these dilated veins may contribute to the infertility problem, and the problem may be correctable. The aim of this work was to evaluate scrotal scintigraphy as a screening measure of varicocele and to study testicular vascular disturbances that may be associated with this illness. This study was conducted on a total of fifty infertile patients with varicocele and eleven normal controls. Patients were grouped into four groups according to clinical classification. All patients and controls were subjected to thorough history and full examination. Using color duplex Doppler sonography, diameters of the pampiniform plexus of veins, testicular arterial diameters and blood velocities were measured in relation to testicular size. Then, scrotal scintigraphy was performed by injection of 20 mCi of 99mTc Pertechnetate I.V. to detect testicular perfusion and radioactive uptake. We have detected 89.5% sensitivity and 90.9% specificity of scintigraphy compared to color duplex Doppler ultrasonography Significant decreases in arterial blood velocity and testicular perfusion were detected specially with large varicoceles which showed also, significant decrease in testicular arterial diameters compared to control. These changes could be correlated to decrease of testicular size. In conclusion, scintigraphy is a simple non invasive, with potential exposure, screening test of varicocele. There are decreases in testicular arterial perfusion, arterial blood velocity and to some extent arterial diameter. These changes may be correlated to testicular growth retardation in this possibly correctable cause of male infertility (au)

  18. PADRÃO ULTRASSONOGRÁFICO DO PARÊNQUIMA, MEDIASTINO E TÚNICAS TESTICULARES EM BOVINOS JOVENS DA RAÇA NELORE

    Directory of Open Access Journals (Sweden)

    Diogo José Cardilli

    2010-12-01

    Full Text Available The aim of the present study was to demonstrate the ultrasonographic patterns of the testicles parenchyma, mediastinum and tunics in young Nellore bulls with absence of echogenicity and relative density changes. Testes of 111 animals underwent clinical and ultrasonographic evaluation at 9, 13, and 15 months of age. Testicular parenchyma presented uniform pattern at low echogenicity. Positive correlation was found between age and testicular mediastinum. Testicular tunics were distinguished only in presence of fluid. The results of this research contribute with andrologic evaluation, allowing early detection of testicular disorders.

  19. Effects of testicular microlithiasis on Doppler parameters: report of three cases

    Directory of Open Access Journals (Sweden)

    Alkan Alpay

    2002-02-01

    Full Text Available Abstract Background Testicular microlithiasis is a rare, usually asymptomatic, non-progressive disease of the testes associated with various genetic anomalies, infertility and testicular tumors. According to our literature search, there is no specific data about Doppler findings in this disease. Case presentation Doppler findings of three cases of testicular microlithiasis during last two years in our institution are presented. Conclusions Although our hypothesis was to find increased Doppler parameters due to intratesticular arterial compression, our findings suggest that there are no Doppler findings specific to testicular microlithiasis.

  20. An unusual case of intra-abdominal testicular torsion: Role of laparoscopy

    Directory of Open Access Journals (Sweden)

    Alfonso Papparella

    2013-01-01

    Full Text Available The authors report a case of intra-abdominal testicular torsion, where laparoscopy has been useful for diagnosis and surgical management. A boy was presented with a left impalpable testis. Laparoscopy revealed a twisted spermatic cord at the inlet pelvis, which ended in a testicular remnant located in the sub-umbilical area. After orchiectomy, the pathologist confirmed testicular atrophy. Diagnosis of intra-abdominal testicular torsion should be considered in patients with impalpable testis and abdominal pain, but could not be excluded in those with no symptoms.

  1. Stage 1 testicular seminoma; Seminomes testiculaire de stade 1

    Energy Technology Data Exchange (ETDEWEB)

    Gross, E.; Champetier, C.; Zaccariotto, A.; Duberge, T. [Departement de radiotherapie, hopital de la Timone, 13 - Marseille (France); Pointreau, Y. [Service de radiotherapie, centre regional universitaire de cancerologie Henry-S.-Kaplan CHU de Tours, Hpital Bretonneau, 37 - Tours (France); Chauvet, B. [Institut Sainte-Catherine, 84 - Avignon (France)

    2010-07-01

    Testicular cancer is rare, representing only 1 % of malignant tumors, but the most common cancer in young men, 15 to 35 years. Adjuvant radiotherapy after orchidectomy in testicular seminoma stage I, reduces risk of relapse. It aims to eradicate micro-metastatic disease in lymph drainage territories. In the case of adjuvant radiotherapy, the relapse-free survival of 96 % with an overall survival of 98 % at 5 years. The irradiation volume is made up of lymph nodes paraaortic which it is possible to add the ipsilateral renal hilum to the testicular lesion. The current recommended dose is 20 Gy in 10 fractions and 2 weeks, usually delivered by two antero-posterior beams. The acute toxicities, mainly represented by nausea and diarrhea are usually quickly resolved to the end of irradiation. Regarding toxicities long-term, preservation of semen should be considered after surgery because of fear of infertility post-treatment. The risk of second cancer associated with exposure to ionizing radiation, albeit small, is especially important to consider these patients to significant life expectancy. Nevertheless, developments in radiotherapy techniques and lower doses and irradiated volumes can probably reduce this risk further. (authors)

  2. Varicocele Repair Improves Testicular Histology in Men with Nonobstructive Azoospermia

    Science.gov (United States)

    Ustuner, Murat; Yilmaz, Hasan; Yavuz, Ufuk; Ciftci, Seyfettin; Saribacak, Ali; Aynur, Bahri Serkan; Yasar, Hikmet; Culha, Mustafa Melih

    2015-01-01

    Objective. To determine the histopathological differences after varicocele repair in testicular tissue in males with nonobstructive azoospermia. Methods. Between 2009 and 2014, 45 men with complete azoospermia and palpable varicocele, presenting with primary infertility of at least 1 year, undergoing varicocele repair at our institution were selected for the study. A standard systematic testicular 6-core Tru-Cut biopsy was performed during varicocele repair. Other biopsies were obtained from each testicle of all patients at the time of microscopic sperm extraction procedure. Results. Nineteen patients were selected for the study. Testicular biopsy specimens were classified as Sertoli cell only on preoperative histopathological analysis in 14 patients. After varicocele repair, focal spermatogenesis (n = 3) and late maturation arrest (n = 2) were found in these patients. Average Johnsen score was significantly increased after varicocelectomy (P = 0.003). Motile sperm was found in one patient on postoperative semen analyses and in 10 more patients in the microscopic sperm extraction procedure. Preoperative high serum follicle stimulating hormone level and venous reflux were significantly and negatively correlated with the increase in average Johnsen score (P varicocele repair. PMID:26601110

  3. Study of the Effect of the Cytotoxic Extract of Bacterium Streptomyces on Epidermoid Malignant Cells of the Oral Cavity

    Directory of Open Access Journals (Sweden)

    M Farahmand

    2004-07-01

    Full Text Available Introduction: It is well known that marine microorganisms have been recognized as an important and untapped resource for novel bioactive compounds. Actinomycetes are gram positive bacteria showing a filamentous growth. They are a group of organisms widespread in nature and play a significant role in the future of drug development. Materials & Methods : Marine bacteria strains of Streptomyces griscoloalbus were isolated from soft coral Sinularia erecta in Persian Gulf. Growth and fermentation character of the Streptomyces griscoloalbus were estimated. Cytotoxic activity of fermentation medium was tested by brine shrimp bioassay. Semi purification on the culture extract was performed. Results: Toxic extract was applied on KB cells ( human epidermoid carcinoma of mouth and results of neutral red test were IC50= 4.19 g/ml from acetone extract and IC 50 = 44.97 g/ml. For methanol extract, cytotologic effects of the acetone extract on KB cells was studied and morphological changes were also studied. Conclusion:The morphological changes in Kb cells due to the cytotoxic extract of the bacteria has made it a good candidate for the production of cytotoxic drugs in the future.

  4. Thiol protease-specific inhibitor E-64 arrests human epidermoid carcinoma A431 cells at mitotic metaphase

    International Nuclear Information System (INIS)

    E-64-d /ethyl (2S, 3S)-3-[(S)-3-methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl]oxirane-2-carboxylate/, a membrane-permeant derivative of the thiol protease-specific inhibitor E-64, was found to arrest human epidermoid carcinoma A431 cells at mitotic metaphase. This effect was dose-dependent with a threshold of 20?g/ml in chemically defined culture medium. Cell cycle analysis by flow cytometry showed that the relative proportion of the G2/M population increased 2.5-fold after treatment of the cells with E-64 (100 ?g/ml) for 5 hr. In addition, time-lapse video analysis showed that E-64-treated cells remained at metaphase for an extended period after rounding-up, whereas untreated cells were able to complete mitosis within 42.0 +/- 5.7 min. Some treated cells were able to complete mitosis, while others did not do so within limits of the authors observation. An approach to the molecular basis of this phenomenon, they have shown that several cellular proteins can be labeled by incubation of cells with radioactive E-64-d

  5. Quiste branquial tipo I: presentación de un caso A type-I brachial cyst: a case report

    Directory of Open Access Journals (Sweden)

    Fidel Castro Pérez

    2010-12-01

    Full Text Available Se presenta el caso de una adolescente de 14 años de edad, raza blanca, del sexo femenino, con antecedentes de salud relativa, que se valoró en la consulta externa del Policlínico Universitario Ernesto Guevara de la Serna de Sandino, Pinar del Río, Cuba. La paciente presentó un cuadro caracterizado por el aumento de volumen superficial de la región lateral derecha superior del cuello, por debajo de la rama horizontal de la mandíbula y por delante del borde anterior del músculo esternocleidomastoideo, cerca del pabellón auricular y la parótida, de aproximadamente 4 cm. de diámetro, móvil, no doloroso, de superficie lisa y consistencia renitente, sin cambios en la coloración de la piel; al examen físico otorrinolaringológico no se encontraron otras alteraciones, posteriormente se realizó un ultrasonido en esa región. El diagnóstico dio como resultado un quiste branquial y se procedió a la exéresis quirúrgica por el equipo de autores del artículo, realizándose estudio anatomopatológico. Los autores presentan las experiencias derivadas de la atención del caso, y revisan la literatura médica sobre el tema con especial referencia al diagnóstico y tratamiento.A Caucasian 14 year-old female adolescent having relative health history was assessed at "Ernesto Guevara de la Serna" Outpatient Clinic in Sandino, Pinar del Rio, Cuba. The patient presented a clinical chart which was characterized by an increase of the superficial volume of the right upper lateral region of neck, below the horizontal branch of the mandible and to the front of the anterior border of sternocleidomastoid muscle, near outer ear and parotid having approximately 4cm of diameter, motile, painless, smooth surface and renitent consistency, without changes in skin color; physical and ENT examinations found no other alterations, subsequently a sonographic study in that region confirmed a brachial cyst that was surgically removed performing pathological studies. The authors presented the experiences derived from this case and the medical literature about the topic was reviewed emphasizing on the diagnosis and treatment.

  6. BIOMETRIA TESTICULAR EM POTROS PURO SANGUE DE CORRIDA COM AUXÍLIO DO ULTRA-SOM / TESTICULAR BIOMETRICS IN THOROUGHBRED FOALS USING ULTRASOUND

    Scientific Electronic Library Online (English)

    Karin Erica, Brass; Joaquin Lopez de, Alda; Neiva Medianeira, Deprá; Flávio Desessards De La, Corte; José Henrique Souza da, Silva; Carlos Antonio Mondino, Silva.

    Full Text Available RESUMO Potros Puro Sangue de Corrida com idades variando de 2 a 24 meses foram submetidos a um estudo biométrico dos testículos com ultra-som. Observou-se um aumento no desenvolvimento testicular a partir dos 12 meses de idade e correlação altamente significativa entre o diâmetro testicular transver [...] sal (altura) e a idade. As imagens do parênquima testicular obtidas até os 5-6 meses de idade eram hipoecogênicas e com o avanço desta, aumentou a intensidade de reflexão até alcançar o padrão do parênquima testicular adulto. Abstract in english SUMMARY A biometric study wrth ultrasound was done in thoroughbred foals from 2 to 24 month old. From 12 month was observed an increase in the testicular development. Also, a significam correlation was found between the ultrasound measure of the transversal testicular diameter (height) and age. The [...] ultrasonographic image of the testicular parenchym was hypoechoic since 5-6 month. The reflexion rate increased u p to reach the adult pattern.

  7. Ecotoxicology and Testicular Damage (Environmental Chemical Pollution: A Review Ecotoxicología y Daño Testicular. (Contaminación Química Ambiental: Revisión

    Directory of Open Access Journals (Sweden)

    Eduardo Bustos-Obregón

    2008-12-01

    Full Text Available This review briefly considers the testicular damage elicited by environmental chemical pollution. It includes a short comment on environmental toxicology as an introduction to environmental chemical pollution, highlighting the importance of this current field of study and its impact on male reproductive health. Furthermore an experimental animal model addressing the effect of organophosphorated agropesticides as a testicular toxicant is presented. Moreover two relevant chemical contaminants and their effect on the testis, such as the classical case of lead and the rarely reported case of Boron on spermatogenesis, are considered. Additionally, the subject of biosentinel species and their relevance for the monitoring of pollution in aquatic and/or terrestrial ecosystems is considered. In conclusión, it should be stressed that environmental health is closely related to the reproductive health of all living beings.Esta revisión considera el daño testicular provocado por la contaminación química ambiental. Incluye un breve comentario sobre toxicología ambiental a modo de introducción respecto a la polución química ambiental y destaca la importancia de este campo de estudio actual y su impacto sobre la salud reproductiva masculina. Además se presenta un modelo experimental animal concerniente al efecto de agropesticidas organofosforados como tóxicos testiculares. Se consideran dos contaminantes químicos relevantes y su efecto en el testículo como son el clásico caso del plomo y el menos conocido caso del boro y sus efectos sobre la espermatogénesis. También se trata el tema de las especies biocentinelas y su importancia para el monitoreo de la evolución de ecosistemas acuáticos y/o terrestres. En conclusión, es necesario insistir que la salud medioambiental está íntimamente relacionada con la salud reproductiva de todos los seres vivos.

  8. Morfometria testicular de cabritos alimentados com óleo de licuri (Syagrus coronata) Testicular morphometry of goats fed licury (Syagrus coronata) oil

    OpenAIRE

    L.P Barbosa; Oliveira, R. L.; T. M. Silva; I.B Jesus; A.F. Garcez Neto; A.R Bagaldo

    2012-01-01

    Determinou-se o desenvolvimento testicular de caprinos pré-púberes alimentados com óleo de licuri (Syagrus coronata) na dieta. Foram utilizados 19 cabritos ¾ Boer, recém-desmamados, com média de idade de três meses. Os animais, submetidos a um período de 75 dias de confinamento, receberam alimentação composta por: farelo de milho, farelo de soja, feno picado de tifton 85 e de óleo de licuri com base na matéria seca. Os animais foram distribuídos em quatro grupos: sem lipídio adicional (n= 5);...

  9. Ecotoxicology and Testicular Damage (Environmental Chemical Pollution): A Review / Ecotoxicología y Daño Testicular. (Contaminación Química Ambiental): Revisión

    Scientific Electronic Library Online (English)

    Eduardo, Bustos-Obregón; Ricardo, Hartley B.

    2008-12-01

    Full Text Available Esta revisión considera el daño testicular provocado por la contaminación química ambiental. Incluye un breve comentario sobre toxicología ambiental a modo de introducción respecto a la polución química ambiental y destaca la importancia de este campo de estudio actual y su impacto sobre la salud re [...] productiva masculina. Además se presenta un modelo experimental animal concerniente al efecto de agropesticidas organofosforados como tóxicos testiculares. Se consideran dos contaminantes químicos relevantes y su efecto en el testículo como son el clásico caso del plomo y el menos conocido caso del boro y sus efectos sobre la espermatogénesis. También se trata el tema de las especies biocentinelas y su importancia para el monitoreo de la evolución de ecosistemas acuáticos y/o terrestres. En conclusión, es necesario insistir que la salud medioambiental está íntimamente relacionada con la salud reproductiva de todos los seres vivos. Abstract in english This review briefly considers the testicular damage elicited by environmental chemical pollution. It includes a short comment on environmental toxicology as an introduction to environmental chemical pollution, highlighting the importance of this current field of study and its impact on male reproduc [...] tive health. Furthermore an experimental animal model addressing the effect of organophosphorated agropesticides as a testicular toxicant is presented. Moreover two relevant chemical contaminants and their effect on the testis, such as the classical case of lead and the rarely reported case of Boron on spermatogenesis, are considered. Additionally, the subject of biosentinel species and their relevance for the monitoring of pollution in aquatic and/or terrestrial ecosystems is considered. In conclusión, it should be stressed that environmental health is closely related to the reproductive health of all living beings.

  10. Pathogenesis and Active Prevention of Testicular Germ Cell Neoplasia

    Directory of Open Access Journals (Sweden)

    Slowikowska-Hilczer J

    2007-01-01

    Full Text Available Most testicular neoplasms originate from fetal germ cells (germ cell tumors [GCT]. Intratubular germ cell neoplasia (ITGCN or testicular carcinoma in situ (CIS are terms used for the state when these cells are present in the seminiferous epithelium. The highest risk of neoplastic lesions occurs in testes with disturbed organogenesis (in our study, 65 %. Genetic, hormonal, and environmental factors are suspected to lead to disturbed testicular organogenesis (dysgenesis, which creates the milieu favorable for GCT development. An external environment can cause a block or delay in fetal germ and somatic cell differentiation. CIS cells in dysgenetic testes of children reveal a predominantly aneuploid DNA pattern (62.2?97.6 % of germ cells and they do not express an RBM protein (present in normal germ cells, this indicates that CIS cells are neoplastic from fetal life on. Most of the neoplastic germ cells die, however, some survive and proliferate, leading to a clonal expansion and giving rise to gonadoblastoma, CIS, and GCT. Neoplastic germ cells located inside underdeveloped testicular tubules have an intratesticular environment favorable for their survival ? this was confirmed by the finding that the highest incidence of neoplastic lesions occurred in patients with partial (90.9 % and mixed gonadal dysgenesis (76.9 %. It was hypothesized that the transformation of CIS into overt GCT may be promoted by gonadotropin action. We found that in gonadal dysgenesis, serum concentrations of FSH and LH reveal highly significant, positive correlations with the number of CIS cells, even in childhood. At present, surgical biopsy of the testis is the only reliable method to detect CIS and hence to actively prevent the development of overt GCT. Accordingly, early bilateral gonadectomy is recommended in all types of disturbance of testicular organogenesis because of the high risk of various neoplastic lesions in dysgenetic testes (86 % of adult patients with retained dysgenetic gonads developed GCT, CIS, gonadoblastoma or combinations. In other risk groups, the most frequently recommended method of CIS treatment is radiotherapy, with the exception of unilateral CIS, for which orchiectomy is the treatment of choice.

  11. Association between testicular dysgenesis syndrome (TDS) and testicular neoplasia: evidence from 20 adult patients with signs of maldevelopment of the testis

    DEFF Research Database (Denmark)

    Skakkebæk, Niels Erik; Holm, Mette; Hoei-Hansen, Christina; Jørgensen, Niels; Rajpert-De Meyts, Ewa

    2003-01-01

    Based on a well established association between testicular cancer and undescended testis and more recent publications on epidemiological links between these disorders and male infertility, we proposed the existence of a testicular dysgenesis syndrome (TDS). In most cases TDS presents with impaired...... of semen sampling and testicular histology. In conclusion, our study of 20 patients with various reproductive abnormalities provided evidence that TDS is a real clinical entity. We speculate that most of these abnormalities are caused by adverse environmental effects rather than specific gene...

  12. Trombocitopenia severa como manifestación de un tumor testicular de células germinales con metástasis cardíaca intracavitaria / Testicular tumor with intracardiac metastasis presenting as severe thrombocytopenia

    Scientific Electronic Library Online (English)

    Germán, Armijo; Patricio, Sanhueza; Marcelo, Morales; Claudio, de la Vega; Alejandro, Ceballos; Carlos, Orfali.

    Full Text Available Se describe el caso de un hombre de 24 años que se presenta con Púrpura trombocitopénico, cuyo estudio ecocardiográfico y tomografía computada demostró masa tumoral ocupando las cavidades derechas. Se evidenció posteriormente un tumor testicular izquierdo con componentes de seminoma y teratoma. Se r [...] esecó el tumor testicular y posteriormente el tumor intracardíaco, con normalización del recuento plaquetario. Abstract in english A 24 year old man presented with severe thrombocytopenia. An intracardiac mass was shown to be a metastasis from a malignant testicular tumor. Resection of the primary tumor and the intracardiac metastasis led to full recovery of thrombocytopenia. [...

  13. Quiste gigante de mesenterio en un recién nacido: Reporte de un caso / Giant mesenteric cyst in a newborn: Report of a case

    Scientific Electronic Library Online (English)

    Martín Noé, Rangel Calvillo.

    2014-03-01

    Full Text Available Se reporta el caso de una recién nacida, quien fuera ingresada al Servicio de Urgencia por distensión abdominal, dolor y vómito. Inicialmente se le dio manejo médico, pero posteriormente le fue identificada una masa en el hemiabdomen derecho que desplazaba a las vísceras. Es por ello que el Servicio [...] de Cirugía Pediátrica decidió realizar intervención quirúrgica. En la cirugía, se encontró una tumoración a expensas del quiste de mesenterio, que posteriormente fue drenado en el transquirúrgico. El postoperatorio fue satisfactorio. El objetivo de este artículo es informar el caso de un neonato con un quiste de mesenterio y efectuar la revisión de la patología con la finalidad de establecer el abordaje diagnóstico y terapéutico. El quiste del mesenterio es una patología muy poco frecuente, el cual se define como cualquier lesión quística localizada en el mesenterio y se subdivide, según su origen, en tumores linfáticos, mesoteliales, urogenitales, dermoides, entéricos y pseudoquísticos. Los casos más frecuentes son los linfangiomas benignos producidos por la proliferación de tejido linfático ectópico. Generalmente se presentan en el mesenterio del intestino delgado o en el epiplón. Respecto al abordaje-diagnóstico, los estudios de imagen, para que sean de mayor utilidad, deben estar orientados con base en la historia clínica y la exploración física, siguiendo un orden en la realización de los mismos. El manejo definitivo es la exéresis o el drenaje, aun en casos asintomáticos. Abstract in english We report the case of a newborn who was admitted for emergency service due to abdominal pain, distension and vomit. Initially medical treatment was given, but subsequently an abdominal mass was identified, so the pediatric surgery service decided to carry out a surgical intervention. At surgery a ma [...] ss at the expense of mesenteric cyst was found. The cyst was drained in the trans-surgical. The postoperative course was satisfactory. The objective of the paper is to report the case of a newborn with a mesenteric cyst and review this pathology in order to establish the diagnosis and therapeutic approach. Mesenteric cyst is a rare disease defined as any cystic lesion in the mesentery. It is divided according to their origin in lymphoid tumors, mesothelial, urogenital, dermoid, and enteric pseudocystic. The most frequent cases are benign lymphangiomas produced by the proliferation of ectopic lymphoid tissue. Usually occur in small bowel mesentery or omentum. Regarding the diagnostic approach, the imaging studies should be oriented on the basis of clinical history and physical examination, following an order in conducting such studies. The definitive management is the excision or drainage, even in asymptomatic cases.

  14. Factores ambientales que influyen en la variabilidad de la producción de quistes de Lingulodinium polyedrum y Scrippsiella trochoidea (Dinophyceae) / Environmental factors influencing the variability of Lingulodinium polyedrum and Scrippsiella trochoidea (Dinophyceae) cyst production

    Scientific Electronic Library Online (English)

    JL, Peña-Manjarrez; G, Gaxiola-Castro; J, Helenes-Escamilla.

    2009-03-01

    Full Text Available Se estudió la variabilidad temporal de las abundancias de quistes de reposo de Lingulodinium polyedrum y Scrippsiella trochoidea en los sedimentos superficiales, así como los quistes temporales y células vegetativas de L. polyedrum en la parte superior de la columna de agua en la Bahía de Todos Sant [...] os (Baja California, México). Las muestras fueron recolectadas mensualmente de enero de 2002 a junio de 2005 en cuatro localidades. El análisis multidimensional escalado y el análisis de similitud mostraron que los quistes de reposo se distribuyen heterogéneamente de acuerdo con el ambiente sedimentario. Los principales factores que influyeron en la producción de quistes de reposo para L. polyedrum son la temperatura superficial, los fosfatos inorgánicos y la abundancia de quistes temporales, mientras que la variabilidad de los quistes temporales se explicó por la abundancia de células planctónicas. Los quistes de reposo de S. trochoidea no tuvieron relación estadística con los factores ambientales considerados. Las escorrentías locales durante la temporada de lluvias y las aguas residuales de la ciudad de Ensenada contribuyen a la eutroficación de la bahía, lo cual es un factor importante para futuros florecimientos donde los nitratos + nitritos inorgánicos disueltos y las horas de luz durante primavera-verano no son l