WorldWideScience
1

Pharmacokinetic and dosimetric characteristics of some thallium isotopes  

International Nuclear Information System (INIS)

Pharmacokinetics is studied, radiation doses to patients when using domestic thallium-201 chloride in diagnosis of the heart ischemic disease is estimated; contribution into the total dose of thallium-201 (1.5 %), thallium-201 (0.2 %) and lead-201 + lead-203 (0.05 %) radionuclide impurities is also determined. Internal doses were estimated for a heterogeneous phantom of a standard man; the calculations were carried out using a computer. Scanning of patients which were treated with radiopharmaceuticals to be diagnosed was carried out using a whole body counter and gamma-chamber. Large intestine, kidneys and thyroid are the critical organs when using thallium-201 chloride. The highest contribution into the dose to organs and the whole body from thallium-200 and thallium-202 impurities being contained in ...

2

Myocardial imaging in patients with Kawasaki disease. Exercise stress imaging and serial studies  

Energy Technology Data Exchange (ETDEWEB)

Thallium-201 myocardial imaging was performed in 80 children with coronary arterial lesions due to Kawasaki disease in order to assess the value of serial and exercise myocardial imagings. In eight of these children, abnormalities of the image were noted. Twenty children had serial thallium studies with an interval of three to 18 months, and five of these showed changes in the image including appearance of a new perfusion defect in one patient and improvement of perfusion defects in four. These changes of the myocardial image were correlated well with coronary angiographic findings obtained within a few days of the isotope studies. It was noted that the changes of the myocardial image were more frequently observed at relatively recent period recovered from Kawasaki disease. Exercise myocardial imaging using a bicycle ergometer was performed in eight children with coronary arterial lesions. In three an evidence of improvement of the myocardial ...

1982-06-01

3

Radiometric measurement of lead-201 and thallium-201 activity in industrial production of thallium chlorides  

International Nuclear Information System (INIS)

The spectrometric methods and equipment for "2"0"1Pb and "2"0"1Tl activity control in the prepared thallium chloride in industrial production are described. Estimation of thallium-201 activity is carried out in accord with the square of summary photopeak caused by #gamma#-quanta at 167 keV energy. Attenuation is paid to spectrometer calibration. 5 refs.; 2 figs.; 2 tabs.

4

First results of preoperative localisation of parathyroid glands adenomas by means of subtraction scintigraphy with technetium-99m and thallium-201  

International Nuclear Information System (INIS)

Eight patients with primary hyperparathyroidism were examined preoperative to locate the affected parathyroid glands. The localisation was done with technetium 99m and thallium 201. This new method seems to be of great value to locate preoperative the affected parathyroid glands. (R.B.).

5

Clinical usefulness of Thallium-201 chloride scintigraphy for evaluation of oral malignant tumors. Relationship between retention index, histological type and tumor involvement  

Energy Technology Data Exchange (ETDEWEB)

In this report we assessed retrospectively the usefulness of Thallium-201 chloride scintigraphy for diagnosing malignant tumors of the maxillofacial region. Thallium-201 chloride scintigraphy was performed on 74 patients with malignant tumors and 8 patients with benign tumors, and a retention index was calculated from the early and delayed scintigrams (delayed accumulation ratio/ early accumulation ratio). This retention index depended on the blood flow of tumors and the affinity of tumors with Thallium-201 chloride. The retention index was large for malignant tumors (avg.: 1.05) and small for benign tumors (avg.: 0.78). Concerning the degree of malignancy (the histological type and the degree of tumor involvement), the retention index was higher in highly malignant tumors (1.20 for poorly-differentiated tumors and 1.19 for aggressive-involvement-type tumors) ...

1999-09-01

6

Localization of abnormal parathyroid glands using thallium-201  

Science.gov (United States)

Ectopically located parathyroid adenomas may be difficult to find during initial neck exploration. They account for over 70 percent of missed adenomas found at reexploration. Preoperative localization of parathyroid adenomas would reduce unnecessary dissection and possibly reduce the number of negative results of initial neck exploration. Before reoperative parathyroid surgery is performed, some means of localization is mandatory to detect ectopic adenomas in the neck and mediastinum. Computed tomography and ultrasonography cannot effectively evaluate the mediastinum. Angiography and venous parathyroid hormone sampling are invasive, costly, and tedious to perform. We have shown that thallium-201 will accurately localize ectopic parathyroid adenomas. All 10 adenomas found in positions not immediately adjacent to the thyroid gland were detected by thallium-201 scintigraphy. One was a mediastinal adenoma ...

1984-07-01

7

Adenosine triphosphate loading thallium-201 myocardial scintigraphy. Optimal dose and diagnostic accuracy  

Energy Technology Data Exchange (ETDEWEB)

Adenosine triphosphate (ATP) is an alternative to dipyridamole or adenosine in thallium-201 myocardial scintigraphy. However, the optimal dose of ATP has not been determined. A Doppler guide wire study showed the coronary flow velocity at a dose of 0.15 mg/kg of ATP was equal or higher than that at 0.14 mg/kg of adenosine or 0.56 mg/kg of dipyridamole. ATP was given intravenously to 67 patients with coronary artery disease at 0.15 mg/kg/min for 6 min. Thallium-201 was injected at 3 min, followed by immediate and delayed (3 hrs) tomographic imaging. There was no serious side effect during examination, although chest pain (26%), dyspnea (17%), and flushing (33%) were common. The sensitivity and specificity to detect coronary artery disease were 98 and 100%, respectively. The sensitivity to detect left anterior descending artery, left circumflex artery, and right coronary artery lesions was 94, 59 and 77%, ...

1995-01-01

8

Visualization of right atrial appendix by Thallium-201 myocardial scintigraphy: concise communication  

Energy Technology Data Exchange (ETDEWEB)

The atrial myocardium has been barely visible with thallium-201 myocardial scintigraphy. This is probably related to the difference in size, distance from anterior chest wall, and small coronary blood flow of the atrium, compared with the ventricle. We have encountered eight cases of visualization of the right atrial appendix (RAA). The RAA was identified from multiple projections in all cases and sometimes confirmed by radionuclide angiocardiography. Evidence derived from ECG, chest radiographs, and cardiac catheterization, indicated that the most important factor in the visualization might be the displacement of the RAA to a more anterior position.

1980-10-01

9

Quantitative thallium-201 scintigraphy after dipyridamole infusion combined with low level exercise in healthy volunteers  

Energy Technology Data Exchange (ETDEWEB)

To establish test specific normal limits for quantitative analysis of uptake and washout of /sup 201/Tl after dipyridamole infusion combined with low level exercise, 20 healthy volunteers were studied with low likelihood of coronary artery disease (CAD) assessed by a stepwise probability analysis based on age, sex, symptoms, resting electrocardiogram, and exercise electrocardiography. Likelihood of CAD in these volunteers was calculated as less than or equal to 1%. After dipyridamole infusion combined with low level exercise, one volunteer complained of headache; no other side effects were observed. There were no chest pain complaints. Maximal hemodynamic changes were achieved during the 6th and 7th min of the test. No ST segment depression was recorded. Visual analysis of the /sup 201/Tl scintigrams was normal in all volunteers. Mean regional washout at 4 h was 44.37%+-2.11%. The regional washout in the 70/sup 0/ LAO view (46.65%+-1.10%) was significantly higher ...

1989-05-01

10

The accuracy and reverse effects of thallium myocardial SPECT using adenosine triphosphate loading in the diagnosis of coronary artery disease. Comparison with other loading methods semiquantitatively  

Energy Technology Data Exchange (ETDEWEB)

The adverse effects and diagnostic accuracy of thallium-201 myocardial SPECT after intravenous infusion of adenosine triphosphate (ATP) were studied and compared with SPECT examinations with other type of loading. The subjects of the study were 147 patients with or without coronary artery disease, who underwent some type of loading SPECT and coronary arteriography (CAG) within 30 days. Myocardial ischemia was evaluated qualitatively in SPECT and was compared with CAG for the diagnostic accuracy of coronary artery disease. The degree of myocardial uptake defect was also calculated semiquantitatively using visual scoring method and compared with coronary artery severity score. The adverse effects occurred in 46.7% of ATP loading SPECT which was more frequent that DIP loading SPECT, but all of them were transient and mild. As for the diagnostic ability the ATP loading SPECT was as effective as other type of loading in qualitative interpretation, ...

1999-09-01

11

Technetium-99m dithiocarbamates as potential agents for brain imaging  

International Nuclear Information System (INIS)

Thallium-201 diethyldithiocarbamate (DDC) behaves like a chemical microsphere and is trapped by spontaneous decomposition in the brain in proportion to regional perfusion. They have shown that the technetium-99m analog, Tc-99m DDC (1), is unsuitable for cerebral perfusion imaging because it does not decompose rapidly enough to be trapped in the brain. With the goal of turning this greater stability of 1 into an advantage, a series of dithiocarbamates with lipophilic or amine groups designed to enhance cerebral uptake and retention was prepared from the following amines by reaction with carbon disulfide and sodium hydroxide: pyrrolidine (2), piperazine (3), 4-benzylpiperazine (4), and 4-(1-piperidino)piperidine (5). These ligands (5 mg) were labelled with Tc-99m in > 95% efficiency (ITLC-SG, saline) by reduction of pertechnetate at room temperature with formamidine sulfinic acid at alkaline pH. In preliminary studies, 4 and 5 show a trend of ...

12

Localization of enlarged parathyroid glands by thallium-201 and technetium-99m subtraction imaging. Gland mass and parathormone levels in primary hyperparathyroidism  

International Nuclear Information System (INIS)

Twenty-two patients, all with surgically proven primary hyperparathyroidism, were studied by TI-201 thallous chloride and Tc-99m pertechnetate subtraction imaging. Fifteen parathyroid adenomata and one hyperplastic gland between 0.33 and 14.8 g were correctly localized in 16 patients. Two adenomata and seven hyperplastic or histologically normal parathyroids between 0.1 g and 1.4 g in seven patients were not localized. One patient had a correctly localized 13.0-g adenoma with a nonlocalized 0.3 g hyperplastic parathyroid gland and there were two false positive localizations. Sensitivity was 64% (glands), and 73% (patients). There was only fair correlation with parathormone (PTH) levels, but these were elevated in all but four of the patients with correctly localized parathyroids. The authors conclude that the imaging procedure is useful but its sensitivity is limited by difficulty in localizing correctly small glands, particularly those of less than 0.5 g, which comprised 29% of those ...

13

Quantitation of Antibody to Non-Hemagglutinating Viruses by Single Radial Hemolysis: Serological Test for Human Coronaviruses  

UK PubMed Central (United Kingdom)

A single radial hemolysis test was developed for quantitation of specific antibody to non-hemagglutinating viruses. With the human coronaviruses as models, this test utilizes the binding properties...Full Text Available

1977-06-01

14

Single photon emission tomography of the pituitary: preliminary communication.  

UK PubMed Central (United Kingdom)

A specific application of single photon emission tomography to the relative quantitation of the pituitary region is described together with the results obtained in 19 patients with pituitary adenoma...Full Text Available

1981-09-01

15

Simultaneous recognition and segmentation of cells: application in C.elegans  

UK PubMed Central (United Kingdom)

Motivation: Automatic recognition of cell identities is critical for quantitative measurement, targeting and manipulation of cells of model animals at single-cell resolution. It has been...Full Text Available

2011-10-15

16

Thallium-201 yields and excitation functions for the lead radioactivities produced by irradiation of natural thallium with 15-60 MeV protons  

International Nuclear Information System (INIS)

Excitation functions, production yields and radionuclidic purities are described for "2"0"1Tl production by the "2"0"3Tl(p,3n) "2"0"1Pb #-># "2"0"1Tl and "2"0"5Tl(p,5n)"2"0"1Pb#->#"2"0"1Tl nuclear reactions. The yields (mCi g"-"1 cm"2/#mu#A-hr) of the parent "2"0"1Pb(9.4hr), as well as the radiocontaminants "2"0"0Pb(21.5hr), sup(202m)Pb(3.62 hr), "2"0"3Pb(52.1 hr) and sup(204m)Pb(1.115 hr) were measured by irradiating a stack of thin natural Tl foils with protons from the 76-in isochronous cyclotron at the Crocker Nuclear Laboratory. The "2"0"1Tl thick-target yield (mCi/#mu#A hr) was calculated for different target thicknesses and corresponding incident proton energies. The excitation functions for the "2"0"3Tl(p,3n)"2"0"1Pb and "2"0"5Tl(p,5n)"2"0"1Pb reactions were measured in the 15-60-MeV energy range. (author).

17

New technetium-99m radiopharmaceuticals for brain imaging  

International Nuclear Information System (INIS)

Radiopharmaceuticals for brain imaging are used for the detection of ischemia, tumours and dementia associatied with disorders of the blood flow in the brain. The current radiopharmaceuticals for brain imaging have various limitations: 2-(F-18)fluoro-2-deoxyglucose (F-18-FDG) has a very short half-life. The physical properties of di-#beta#-(piperidinoethyl)-(Se-75)selenide (Se-75-PIPSE) and di-#beta#-(morpholinoethyl)-(Se-75)-selenide (Se-75-MOSE) are not ideal. Thallium-201 diethyldithricarbamate (T1-201-DDC) has unfavourable nuclidic characteristics, limited availability, a long half-life and high cost. I-123 in N-isopropyl-p-iodoamphetamine (I-123-IMP) and N,N,N'-trimethyl-N'-(2-hydroxy-3-methyl-5-iodobenzyl)-1,3-propanediamine (I-123-HIPDM) are not freely available and are expensive. N-13-labelled ammonia has a very short half-life. Technetium-99m hexamethylpropyleneamineoxime (Tc-99m-HM-PAO) is unstable both in vitro and in vivo and has a ...

1988-08-01

18

Effects of ischemic-like insult on myocardial /sup 201/Tl accumulation  

Energy Technology Data Exchange (ETDEWEB)

Despite extensive clinical use of thallium-201 (/sup 201/Tl) for myocardial imaging, the effect of ischemia on myocardial accumulation and release of /sup 201/Tl independent of flow has not been fully defined. Therefore, myocardial accumulation of /sup 201/Tl in response to ischemic-like myocardial injury was assessed in vitro using the cultured fetal mouse heart preparation. Cultured fetal mouse hearts (n . 311) were subjected to injury simulating ischemia by deprivation of oxygen and oxidizable substrates for periods ranging from 15 minutes to 10 hours. The extent of irreversible injury was determined by the percentage of lactic dehydrogenase (LDH) lost from the hearts to the culture medium during recovery from injury. Injury was essentially reversible at 1 hour of insult. The fraction of /sup 201/Tl content in injured compared with control hearts was not significantly lower after 1 hour of insult. By 3 hours of insult, irreversible injury as ...

1983-04-01

19

Single-crystalline cadmium telluride anodic oxidation kinetics  

Science.gov (United States)

The authors have determined quantitative characteristics for oxide films forming on (111) surfaces of cadmium telluride single crystals on anodic oxidation in 0.1 M KOH: the constants in the Guenterschulze-Betz equation and the film growth constant, which is 2.4 nm/V, from which the activation energy for cadmium telluride electrooxidation has been calculated.

1988-10-10

20

Prediction of the compressive strength of vertebral bodies of the lumbar spine by quantitative computed tomography.  

Science.gov (United States)

The ultimate compressive strength of 36 thoracolumbar vertebrae was determined experimentally. In addition, the trabecular bone mineral content was measured by single energy quantitative computed tomography. The areas of fractured endplates were also determined by computed tomography. The results show that a linear relationship exists between the compressive strength and the product of bone density and endplate area. These data allow an in vivo prediction of vertebral body strength using a noninvasive method with a standard error of estimate amounting to less than 0.95 kN. PMID:3212488

1988-01-01

21

Partial unmixing as a tool for single surface class detection and time series analysis  

British Library Electronic Table of Contents (United Kingdom)

In this paper we present the results of time series analysis for a coal mining region based on partial unmixing. We test the method also known as mixture tuned matched filtering on an eight image Landsat 5 TM and Landsat 7 ETM+ time series covering the period from 1987 to 2003. Common change detection methods often include the comparison of two interactively generated classification results, such as derived from Maximum Likelihood classification. These approaches often yield highly accurate results. However, disadvantages include a strong analyst bias and hardly repeatable results. For a quantitative monitoring of a single surface class' development over time they are often not recommendable. Our goal was to test an unbiased quantitative way to assess the development of coal surfaces, such...

2008-01-01

22

Study of the natural and passive oxide films formed on Ni-Mo single crystal alloys by ion channelling and nuclear microanalysis  

Energy Technology Data Exchange (ETDEWEB)

The chemical properties of alloys in a given environment are to a large extent governed by the surface composition. Changes of the surface composition during passivation are important features in this respect. Previous studies of single crystal Ni-Mo alloys surfaces have been reported. The aim of this work was to obtain quantitative data, for the natural oxide and the passive films formed on Ni-6% Mo(100) and (110) alloys, using Rutherford backscattering spectroscopy and nuclear reaction analysis.

1988-07-01

23

Study of the natural and passive oxide films formed on Ni-Mo single crystal alloys by ion channelling and nuclear microanalysis  

International Nuclear Information System (INIS)

The chemical properties of alloys in a given environment are to a large extent governed by the surface composition. Changes of the surface composition during passivation are important features in this respect. Previous studies of single crystal Ni-Mo alloys surfaces have been reported. The aim of this work was to obtain quantitative data, for the natural oxide and the passive films formed on Ni-6% Mo(100) and (110) alloys, using Rutherford backscattering spectroscopy and nuclear reaction analysis. (author).

1987-10-19

24

Position-Dependent Electrostatic Protection against Protein Aggregation  

British Library Electronic Table of Contents (United Kingdom)

Proteins with a high propensity to aggregate can be largely prevented from doing so with surprisingly small changes to their primary structure. By using a combination of rational design and quantitative measurements of aggregation rates, we show that adding a single charge in specific "gatekeeper" regions is sufficient to change the timescale for amyloid fibril growth from minutes to weeks, thereby dramatically reducing the efficiency of this process.

2009-01-01

25

An intercomparison of computer assisted date processing and display methods in radioisotope scintigraphy using mathematical tumours  

International Nuclear Information System (INIS)

Several computer assisted processing and display methods are evaluated using a series of 100 normal brain scintigrams, 50 of which have had single 'mathematical tumours' superimposed. Using a standard rating system, or in some cases quantitative estimation, LROC curves are generated for each method and compared. (author).

27

Visualization and void fraction measurements of refrigerant flow in a refrigerator by neutron radiography  

Energy Technology Data Exchange (ETDEWEB)

The refrigerant two-phase flows in a distributor and a simulated plate heat exchanger with a single passage used in a compression-type refrigerator were visualized by real-time neutron radiography. For a distributor, the liquid fraction in the each tube was measured by some image processing method. On the other hand, for a plate heat exchanger, the two-dimensional distribution of void fraction was measured quantitatively by the umbra method. As a result, it was shown that the dynamic behaviors of refrigerant at the inlet of the section strongly affected on the performance, that is, a distribution performance of a distributor and a liquid distribution in a plate heat exchanger. (author)

2000-07-01

28

Single parameter analysis of hysteretic magnetic flux trapping in high T{sub c} superconductor ribbon  

Energy Technology Data Exchange (ETDEWEB)

This paper described the application of an AC surface probe, similar to presently used eddy current probes, to the measurement of DC transport critical currents and critical state dissipation in high {Tc} superconductors. It has been shown that the probe can provide quantitative measurement of the full field penetration in superconducting samples by measuring the response of AC induced screening currents for superconducting materials in the form of tapes with overlayers of silver. In this manner, the AC probe can be used to replace the contact DC probe for determining critical currents in a noncontacting and local manner suitable for scanning over or along the sample.

1992-10-01

29

Single parameter analysis of hysteretic magnetic flux trapping in high T_c superconductor ribbon  

International Nuclear Information System (INIS)

This paper described the application of an AC surface probe, similar to presently used eddy current probes, to the measurement of DC transport critical currents and critical state dissipation in high T_c superconductors. It has been shown that the probe can provide quantitative measurement of the full field penetration in superconducting samples by measuring the response of AC induced screening currents for superconducting materials in the form of tapes with overlayers of silver. In this manner, the AC probe can be used to replace the contact DC probe for determining critical currents in a noncontacting and local manner suitable for scanning over or along the sample.

1992-07-19

30

Single parameter analysis of hysteretic magnetic flux trapping in high T[sub c] superconductor ribbon  

Energy Technology Data Exchange (ETDEWEB)

This paper described the application of an AC surface probe, similar to presently used eddy current probes, to the measurement of DC transport critical currents and critical state dissipation in high [Tc] superconductors. It has been shown that the probe can provide quantitative measurement of the full field penetration in superconducting samples by measuring the response of AC induced screening currents for superconducting materials in the form of tapes with overlayers of silver. In this manner, the AC probe can be used to replace the contact DC probe for determining critical currents in a noncontacting and local manner suitable for scanning over or along the sample.

1992-01-01

31

Omic Approaches in Environmental Issues  

British Library Electronic Table of Contents (United Kingdom)

Biomonitoring requires the application of batteries of different biomarkers, as environmental contaminants induce multiple responses in organisms that are not necessarily correlated. Omic technologies were proposed as an alternative to conventional biomarkers since these techniques quantitatively monitor many biological molecules in a high-throughput manner and thus provide a general appraisal of biological responses altered by exposure to contaminants. As the studies using omic technologies increase, it is becoming clear that any single omic approach may not be sufficient to characterize the complexity of ecosystems. This work aims to provide a preliminary working scheme for the use of combined transcriptomic and proteomic methodologies in environmental biomonitoring. There are difficulti...

2011-01-01

32

Correlation of coke microstructure and properties  

Science.gov (United States)

Coke petrography could be useful for improving blast furnace coke properties and for solving cokemaking production problems. To do this, quantitative correlations between coke structure, coal properties and carbonization conditions, and coke properties are useful, if not essential. Some examples of correlations of this type were presented in this paper. Specifically, microstructural parameters of cokes produced in Inland Steel Company's pilot scale coke oven were correlated with the rank and blend proportions of the parent coal, with the reactivity of the coke, and with the ASTM stability of cokes prepared from single coals.

1982-01-01

33

Intra-cellular transport of single-headed molecular motors KIF1A  

CERN Document Server

Motivated by recent experiments on KIF1A, a representative member of single-headed kinesin motor proteins family, we develop a theoretical model of intra-cellular transport by mutually interacting molecular motors. The model explicitly accounts not only for the hydrolysis of ATP, but also for the ratchet mechanism which is believed to drive each individual KIF1A motor. We study the model by a combination of analytical and numerical techniques. A remarkable feature of this model is that all the parameters in it can be completely evaluated from experimental data. Our results in the dilute limit are in excellent quantitative agreement with the empirical data from single molecule experiments. In the high density regime the predictions of the model also agree qualitatively with the corresponding experimental observations. We derive a phase diagram that shows the influence of hydrolysis and Langmuir kinetics on the collective ...

2005-01-01

34

Quantitative pharmacological analysis of 2-125I-iodomelatonin binding sites in discrete areas of the chicken brain  

Energy Technology Data Exchange (ETDEWEB)

The authors have localized and characterized 2-125I-iodomelatonin binding sites in the chicken brain using in vitro quantitative autoradiography. Binding sites were widely distributed throughout the chicken brain, predominantly in regions associated with the visual system. The specific binding of 2-125I-iodomelatonin to discrete chicken brain areas was found to be saturable, reversible, and of high affinity. The specific binding of 2-125I-iodomelatonin (75 pm) was quantitated for 40 identifiable brain regions. Eight brain regions were chosen for binding characterization and pharmacological analysis: optic tectum, Edinger-Westphal nucleus, oculomotor nucleus, nucleus rotundus, ventral supraoptic decussation, ventrolateral geniculate nucleus, neostriatum, and ectostriatum. These regions showed no rostral-caudal gradient in 2-125I-iodomelatonin specific binding, and saturation analysis revealed a single class of high-affinity ...

1991-09-01

35

Quantitative imaging of turbulent and reacting flows  

Energy Technology Data Exchange (ETDEWEB)

Quantitative digital imaging, using planar laser light scattering techniques is being developed for the analysis of turbulent and reacting flows. Quantitative image data, implying both a direct relation to flowfield variables as well as sufficient signal and spatial dynamic range, can be readily processed to yield two-dimensional distributions of flowfield scalars and in turn two-dimensional images of gradients and turbulence scales. Much of the development of imaging techniques to date has concentrated on understanding the requisite molecular spectroscopy and collision dynamics to be able to determine how flowfield variable information is encoded into the measured signal. From this standpoint the image is seen as a collection of single point measurements. The present effort aims at realizing necessary improvements in signal and spatial dynamic range, signal-to-noise ratio and spatial resolution in the imaging system as ...

1993-12-01

36

Quantitative bone and 67Ga scintigraphy in the differentiation of necrotizing external otitis from severe external otitis  

Energy Technology Data Exchange (ETDEWEB)

Qualitative technetium Tc 99m bone scintigraphy using phosphate compounds and gallium 67 scintigraphy were described as a helpful means in diagnosing necrotizing external otitis (NEO). They were, however, claimed to be nonspecific. Quantitative Tc 99m methylene diphosphonate bone scintigraphy and gallium 67 scintigraphy were performed in eight patients with NEO and in 20 patients with severe external otitis, in order to prove usefulness of scintigraphy in the diagnosis of NEO. Ratios of lesion to nonlesion for bone scintigraphy were 1.67 {plus minus} 0.16 in patients with NEO and 1.08 {plus minus} 0.09 in patients with severe external otitis, and for gallium 67 scintigraphy they were 1.35 {plus minus} 0.24 in NEO patients and 1.05 {plus minus} 0.03 in patients with severe external otitis. There was no difference in uptake between diabetic patients with severe external otitis and nondiabetic patients. The scintigraphic studies were also evaluated using a qualitative ...

1991-06-01

37

Quantitative bone and 67Ga scintigraphy in the differentiation of necrotizing external otitis from severe external otitis  

International Nuclear Information System (INIS)

Qualitative technetium Tc 99m bone scintigraphy using phosphate compounds and gallium 67 scintigraphy were described as a helpful means in diagnosing necrotizing external otitis (NEO). They were, however, claimed to be nonspecific. Quantitative Tc 99m methylene diphosphonate bone scintigraphy and gallium 67 scintigraphy were performed in eight patients with NEO and in 20 patients with severe external otitis, in order to prove usefulness of scintigraphy in the diagnosis of NEO. Ratios of lesion to nonlesion for bone scintigraphy were 1.67 #+-# 0.16 in patients with NEO and 1.08 #+-# 0.09 in patients with severe external otitis, and for gallium 67 scintigraphy they were 1.35 #+-# 0.24 in NEO patients and 1.05 #+-# 0.03 in patients with severe external otitis. There was no difference in uptake between diabetic patients with severe external otitis and nondiabetic patients. The scintigraphic studies were also evaluated using a qualitative scoring method (scores 0 to ...

38

One-photon two-electron processes in helium close to the double ionization threshold; Diexcitation electronique de l'helium par un photon au voisinage du seuil de double ionisation  

Energy Technology Data Exchange (ETDEWEB)

This work presents a study of the {sup 1}P{sup 0} excited states of He that can be reached by absorption of a single photon carrying an energy close to the double ionization threshold (DIT) (79 eV). Above the DIT, these states are the double continuum states; below, they are the double excited states. These two types of states are tightly coupled to the single continuum states with or without excitation of the residual ion He{sup +}, owing to their degeneracy in energy. In a one-photon process, these states can only be formed owing to the electronic correlations in the system which must be well described to obtain quantitative good results. Our study is a part of the work which aims at a united description of all these doubly excited, ionized-excited, and double continuum states. We use the Hyperspherical R-Matrix with Semiclassical Outgoing Waves (HRM-SOW) method, initially dedicated to double photoionization studies. We ...

2007-04-15

39

Confirmation of quantitative trait loci for resistance to multiple-HG types of soybean cyst nematode (Heterodera glycines Ichinohe)  

British Library Electronic Table of Contents (United Kingdom)

Genetic analysis of resistance of plant introduction (PI) 438489B to soybean cyst nematode (SCN) have shown that this PI is highly resistant to many SCN HG types. However, validation of the previously detected quantitative trait loci (QTL) has not been done. In this study, 250 F2:3 progeny of a Magellan (susceptible)??PI 438489B (resistant) cross were used for primary genetic mapping to detect putative QTL for resistance to five SCN HG types. QTL confirmation study was subsequently conducted using F6:7 recombinant inbred lines (RILs) derived from the same cross. Simple sequence repeat (SSR) and single nucleotide polymorphism (SNP) markers were employed for molecular genotyping. Interval mapping (IM), permutation tests, cofactor selection, and composite interval mapping (CIM) were performe...

2011-01-01

40

Analysis of the quantitative structure activity relationship of technetium-99m-labeled diaminedithiol (DADT) and propyleneamineoxime (PAO) brain blood flow analogues  

Energy Technology Data Exchange (ETDEWEB)

In the search for new brain imaging agents for use with single photon emission computed tomography (SPECT), quantitative structure activity relationship (QSAR) analysis of the correlations between initial brain uptake and physicochemical parameters like lipophilicity, log P, molecular weight, log MW and log U/D (undissociated/dissociated), of the {sup 99m}Tc-DADT (diaminedithiol) complexes and {sup 99m}Tc-PAO (propyleneaminoxime) complexes have been analyzed. High correlations are found for both the {sup 99m}Tc-DADT complexes (r = 0.94) and for the {sup 99m}Tc-PAO complexes (r = 0.83) which are significant at 99.9 and 99.5 percentile level, respectively. These results will help the further design of better ligands for {sup 99m}Tc in brain imaging. (author).

1991-01-01

41

Quantitation of Antibiotics by High-Pressure Liquid Chromatography: Cephalothin  

UK PubMed Central (United Kingdom)

A technique for quantitative determination of cephalothin and desacetylcephalothin in serum using a method based on high-pressure liquid chromatography is described. Both compounds were quantitatively...Full Text Available

1978-02-01

42

Stochastic kinetics of ribosomes: single motor properties and collective behavior  

CERN Document Server

Synthesis of protein molecules in a cell are carried out by ribosomes. A ribosome can be regarded as a molecular motor which utilizes the input chemical energy to move on a messenger RNA (mRNA) track that also serves as a template for the polymerization of the corresponding protein. The forward movement, however, is characterized by an alternating sequence of translocation and pause. Using a quantitative model, which captures the mechanochemical cycle of an individual ribosome, we derive an {\\it exact} analytical expression for the distribution of its dwell times at the successive positions on the mRNA track. Inverse of the average dwell time satisfies a ``Michaelis-Menten-like'' equation and is consistent with the general formula for the average velocity of a molecular motor with an unbranched mechano-chemical cycle. Extending this formula appropriately, we also derive the exact force-velocity relation for a ribosome. Often many ribosomes simultaneously move on ...

2009-01-01

43

Quantitative model of vapor dominated geothermal reservoirs as heat pipes in fractured porous rock  

Science.gov (United States)

We present a numerical model of vapor-dominated reservoirs which is based on the well-known conceptual model of White, Muffler, and Truesdell. Computer simulations show that upon heat recharge at the base, a single phase liquid-dominated geothermal reservoir in fractured rock with low matrix permeability will evolve into a two-phase reservoir with B.P.D. (boiling point-for-depth) pressure and temperature profiles. A rather limited discharge event through cracks in the caprock, involving loss of only a few percent of fluids in place, is sufficient to set the system off to evolve a vapor-dominated state. The attributes of this state are discussed, and some features requiring further clarification are identified. 26 refs., 5 figs.

1985-03-01

44

Quantitative 1-123 IMP SPECT, MR imaging, and neuropsychologic testing in AIDS dementia  

International Nuclear Information System (INIS)

The authors have performed I-123 IMP single- photon emission CT (SPECT) brain imaging on seven mildly demented patients with acquired immunodeficiency syndrome (AIDS) and on seven normal subjects. Pixel-intensity histograms have been analyzed for the fraction of pixels in the lowest quartile of the intensity range. This fraction (F) averaged 17.7% (standard deviation [SD] = 4.3) in the AIDS group and 12.6 (SD = 4.7) in the normal group (P <.05). Regression analysis of neuropsychological testing (NPT) scores vs F yielded a correlation coefficient of.71. The presence or degree of atrophy did not correlate with F or NPT scores.

45

QTL mapping in outbred half-sib families using Bayesian model selection.  

Science.gov (United States)

In this article, we propose a model selection method, the Bayesian composite model space approach, to map quantitative trait loci (QTL) in a half-sib population for continuous and binary traits. In our method, the identity-by-descent-based variance component model is used. To demonstrate the performance of this model, the method was applied to map QTL underlying production traits on BTA6 in a Chinese half-sib dairy cattle population. A total of four QTLs were detected, whereas only one QTL was identified using the traditional least square (LS) method. We also conducted two simulation experiments to validate the efficiency of our method. The results suggest that the proposed method based on a multiple-QTL model is efficient in mapping multiple QTL for an outbred half-sib population and is more powerful than the LS method based on a single-QTL model. PMID:21487433

2011-04-13

46

On the relationship between gender and perceptual language learning styles: the case of Iranian academic EFL learners  

British Library Electronic Table of Contents (United Kingdom)

In the past few decades, research on gender and language learning styles (LLSs) across various EFL/ESL contexts has received remarkable attention. From these studies, a multitude of contradictory and heterogeneous findings has been observed which justify additional research in SLA contexts in general and EFL contexts like Iran in particular. Hence, the present study attempted to explore the relationship between Iranian EFL students' perceptual learning styles and gender. For this aim, a 32-item questionnaire was administered to 105 EFL students at Ilam University, Iran. Results of quantitative research and statistical analysis of findings indicated that both male and female students inclined to be bimodal learners who were visual/non-verbal (V/NV) rather than being trimodal or single learn...

2011-01-01

47

Mapping soil organic matter using the topographic wetness index: A comparative study based on different flow-direction algorithms and kriging methods  

British Library Electronic Table of Contents (United Kingdom)

Terrain attributes derived from digital elevation models have been used widely for mapping soil organic matter (SOM). Among these attributes, the topographic wetness index (TWI), an index for quantitatively indicating the balance between water accumulation and drainage conditions at the local scale, has been shown to correlate with SOM. However, TWIs used in most studies are calculated using a single-flow-direction (SFD) algorithm, which assumes that all water from a grid cell flows into only one neighboring cell. This assumption is not always valid, especially in areas with low relief where movement of water may be divergent. To overcome this SFD limitation, a multiple-flow-direction (MFD) algorithm has been developed, which distributes flow from a grid cell to several downslope neighbors...

2010-01-01

48

Capturing recrystallization of metals with a multi-scale materials model  

Energy Technology Data Exchange (ETDEWEB)

The final report for a Laboratory Directed Research and Development project entitled, ``Capturing Recrystallization of Metals in a Multiscale Materials Model'' is presented. In this project, deformation and recrystallization processes have been followed experimentally and theoretically in order to incorporate essential mechanisms from the defect (dislocation) and grain size length scales. A nonlinear rotational gradient theory has been developed which enables the incorporation of microstructural parameters. The evolution of these parameters during deformation and recrystallization has been characterized qualitatively and quantitatively, applying various electron optic techniques ranging over several length scales. The theoretical and experimental framework developed is general. It has been exemplified by an application to recrystallization in single crystals and bicrystals of aluminum. The recrystallization process has been ...

2000-04-01

49

Time-Resolved Aerosol Collector for CCSEM/EDX Single Particle Analysis  

Energy Technology Data Exchange (ETDEWEB)

An automated Time Resolved Aerosol Collector (TRAC) has been developed for sequential sampling of field-collected aerosols for laboratory-based Computer Controlled Scanning Electron Microscopy/Energy Dispersed X-ray (CCSEM/EDX) single particle analysis. The collector is optimized for use of grid-supported 20 nm carbon films as deposition substrates. The carbon films have low enough X-ray background to permit EDX analysis down to 0.1-0.2 ?m particles, including detection of low-Z elements: C, N, & O. The TRAC provides unattended sampling onto a set of 151 individual grids, at sequential time intervals as short as 1 min. After collection, the samples are sealed and refrigerated pending analysis. The utility of the TRAC-CCSEM/EDX approach is exemplified using the aerosol samples collected during the Texas 2000 Air Quality Studies (Aug. 15 ? Sept. 15, 2000). We are able to quantitatively follow the time evolution in the relative contribution of ...

2003-01-02

50

Dimensionless energy confinement scaling in W7-AS  

International Nuclear Information System (INIS)

Energy confinement in W7-AS has been analyzed in terms of dimensionally exact form free functions employing Bayesian probability theory. The confinement function was set up as a linear combination of dimensionally exact power law terms as already proposed very early by Connor and Taylor. Generation of this expansion basis is dictated by the basic plasma model which one assumes. Based upon data accumulated in W7-AS, which contains the energy content for a wide variety of variable settings, predictions for single variable scans are made. The scaling functions for density and power scans, respectively, are in quantitative agreement with data collected in W7-AS. The result of a single variable scan is therefore already hidden in the data obtained for arbitrary variable choices and can be extracted from the latter by a proper data analysis. Furthermore, the optimal model for the description of the global transport in W7-AS is ...

1999-12-01

51

Rapid laser fluorometric method for the determination of uranium in soil, ultrabasic rock, plant ash, coal fly ash and red mud samples  

International Nuclear Information System (INIS)

A simple and rapid laser fluorometric determination of trace and ultra trace level of uranium in a wide variety of low uranium content materials like soil, basic and ultra basic rocks, plant ash, coal fly ash and red mud samples is described. Interference studies of some common major, minor and trace elements likely to be present in different geological materials on uranium fluorescence are studied using different fluorescence enhancing reagents like sodium pyrophosphate, orthophosphoric acid, penta sodium tri-polyphosphate and sodium hexametaphosphate. The accurate determination of very low uranium content samples which are rich in iron, manganese and calcium, is possible only after the selective separation of uranium. Conditions suitable for the quantitative single step extraction of 25 ng to 20 #mu#g uranium with tri-n-octylphosphine oxide and single step quantitative stripping with dilute neutral ...

1999-10-01

52

Rainfall effect on single-vehicle crash severities using polychotomous response models.  

Science.gov (United States)

As part of the Wisconsin road weather safety initiative, the objective of this study is to assess the effects of rainfall on the severity of single-vehicle crashes on Wisconsin interstate highways utilizing polychotomous response models. Weather-related factors considered in this study include estimated rainfall intensity for 15 min prior to a crash occurrence, water film depth, temperature, wind speed/direction, stopping sight distance and deficiency of car-following distance at the crash moment. For locations with unknown weather information, data were interpolated using the inverse squared distance method. Non-weather factors such as road geometrics, traffic conditions, collision types, vehicle types, and driver and temporal attributes were also considered. Two types of polychotomous response models were compared: ordinal logistic and sequential logistic regressions. The sequential logistic regression was tested with forward and backward formats. Comparative ...

2009-08-14

53

Pulmonary emphysema quantitation with Computed Tomography. Comparison between the visual score with high resolution CT, expiratory density mask with spiral CT and lung function studies; Valutazione quantitativa dell`enfisema polmonare mediante Tomografia Computerizzata. Confronto tra il punteggio visivo con alta risoluzione nell`inspirazione, maschera della densita` automatica con Tomografia Computerizzata spirale nell`espirazione ed esami funzionali respiratori  

Energy Technology Data Exchange (ETDEWEB)

CT is the most accurate method to detect pulmonary emphysema in vivo. They compared prospectively two different methods for emphysema quantitation in 5 normal volunteers and 20 consecutive patients with chronic obstructive pulmonary disease (COPD). All subjects were submitted to function tests and HRCT; three scans were acquired at preselected levels during inspiration. The type and extent of pulmonary emphysema were defined by two independent observers under blind conditions. Disagreements were subsequently settled by consent. All subjects were also examined with expiratory spiral CT using a density mask program, at two different cut-off levels (-850,-900 HU). Visual score and expiratory spiral density mask values (-850 HU) were significantly correlated (r = 0.86), but the visual extent of emphysema was always higher than shown by expiratory spiral CT. The emphysema extent assessed with both CT methods correlated with the function result of expiratory airflow ...

1997-04-01

54

Pulmonary emphysema quantitation with Computed Tomography. Comparison between the visual score with high resolution CT, expiratory density mask with spiral CT and lung function studies  

International Nuclear Information System (INIS)

CT is the most accurate method to detect pulmonary emphysema in vivo. They compared prospectively two different methods for emphysema quantitation in 5 normal volunteers and 20 consecutive patients with chronic obstructive pulmonary disease (COPD). All subjects were submitted to function tests and HRCT; three scans were acquired at preselected levels during inspiration. The type and extent of pulmonary emphysema were defined by two independent observers under blind conditions. Disagreements were subsequently settled by consent. All subjects were also examined with expiratory spiral CT using a density mask program, at two different cut-off levels (-850,-900 HU). Visual score and expiratory spiral density mask values (-850 HU) were significantly correlated (r = 0.86), but the visual extent of emphysema was always higher than shown by expiratory spiral CT. The emphysema extent assessed with both CT methods correlated with the function result of expiratory airflow ...

1997-01-01

55

Enzyme-induced growth of silver nanoparticles studied on single particle level  

Energy Technology Data Exchange (ETDEWEB)

Based on their interesting properties, metal nanoparticles show the potential as an analytical tool in electronic (Burmeister et al. 2004), optical (Yguerabide and Yguerabide 1998), and catalytic applications (Liu 2006). Their characteristics depend on the composition, shape, and size of the single particles. These various properties are utilized in many different approaches such as optics, magnetics (Lang et al. 2007), and laser technology (Csaki et al. 2007). We investigated an alternative method for the synthesis of nanoparticles. In this case, an enzyme, horseradish peroxidase, induces a silver deposition and replaces a metal nanoparticle as the reaction seed. Depending on the reaction time, we could obtain particles in a range of few nanometers up to more than 250 nm. For a better understanding of the enzymatic silver deposition process, the silver particles produced by this process were analyzed by SEM, TEM, and atomic force microscopy (AFM) on a ...

2009-05-15

56

Validation of biological markers for quantitative risk assessment.  

UK PubMed Central (United Kingdom)

The evaluation of biological markers is recognized as necessary to the future of toxicology, epidemiology, and quantitative risk assessment. For biological markers to become widely accepted, their validity...Full Text Available

1991-01-01

57

From Quantitative Microscopy to Automated Image Understanding  

UK PubMed Central (United Kingdom)

Quantitative microscopy has been extensively used in biomedical research and has provided significant insights into structure and dynamics at the cell and tissue level. The entire procedure...Full Text Available

2004-01-01

58

Studies on the interaction of lidocaine with plasma proteins  

Energy Technology Data Exchange (ETDEWEB)

This study sought to quantitate lidocaine's interaction with alpha-1-acid glycoprotein (AAG), human serum albumin (HSA), and AAG in the presence of HSA, and to determine the extent of displacement of lidocaine from its binding site(s) by selected cardiovascular drugs (dipyridamole, disopyramide and quinidine). Since the limited experimental work reported in this area has involved the use of a single lidocaine concentration, this study involved the evaluation of a range of lidocaine concentrations. Lidocaine interaction with plasma proteins (AAG and HSA) was studied at 37/sup 0/C using an isothermal equilibrium dialysis system and /sup 14/C-lidocaine HCl. A dialysis membrane (M.W. cutoff 12,000 to 14,000) separated the two chambers of each dialysis cell. The extent of /sup 14/C-lidocaine dialysis was studied with respect to both drug and protein concentrations. Aliquots of each chamber of each of the cells were subjected to liquid ...

1985-01-01

59

Selective dissolution and surface enrichment of alloy components of passivated Fe 18Cr and Fe 18Cr3Mo single crystals  

International Nuclear Information System (INIS)

The possible surface enrichment of chromium and molybdenum during dissolution of Fe18Cr (110) and Fe18Cr3Mo (110) alloys at constant potentials in the passive region is elucidated by taking into account quantitative information on partial dissolution rates of alloy components as measured by #gamma#-spectrometry and on chemical composition of passivating films as measured by ESCA and AES. When combining results from all methods it is found that chromium under all conditions is enriched in the passivating films. An accumulation of chromium in the alloy is also indicated. For molybdenum, an enrichment in the passive film is observed at -0.2 V (SCE), whereas in the potential interval 0.1 - 0.9 V, the molybdenum enrichment as determined by ESCA and AES is hardly significant. On the other hand, #gamma#-spectrometry gives a clear indication of molybdenum enrichment in both potential. (author).

2008-12-30

60

Quantitative CT assessment of proximal femoral bone density. An experimental study concerning its correlation to breaking load for femoral neck fractures  

International Nuclear Information System (INIS)

Purpose: In an experimental study, the correlation between the trabecular bone density of the different regions of the proximal femur and the fracture load in the setting of femoral neck fractures was examined. Methods: The bone mineral density 41 random proximal human femora was estimated by single-energy quanitative CT (SE-QCT). The trabecular bone density was measured at the greatest possible extracortical volume at midcapital, midneck and intertrochanteric level and in the 1 cm"3 volumes of the centres of these regions in a standardised 10 mm thick slice in the middle of the femoral neck axis (in mg/ml Ca-hydroxyl apatite). The proximal femora were then isolated and mounted on a compression/bending device under two-legged stand conditions and loaded up to the point when a femoral neck fracture occurred. Results: Statistical analysis revealed a linear correlation between the trabecular bone density and the fracture load for the greater regions, with the highest ...

61

Pullout behavior of steel fibers from cement-based composites  

Energy Technology Data Exchange (ETDEWEB)

A comprehensive experimental program on pullout tests of steel fibers from cement based matrices is described. A specially designed single fiber pullout apparatus was used to provide a quantitative determination of interfacial properties that are relevant to toughening brittle materials through fiber reinforcement. The parameters investigated included a specially designed high strength cement based matrix called Densified Small Particles system (DSP), a conventional mortar matrix, fiber embedment length, and the fiber volume fraction. The mediums from which the fiber was pulled included a control mortar mix without fibers, a mortar mix with 3, and 6 percent fibers by volume. The results indicate that: (1) the dense DSP matrix has significantly improved interfacial properties as compared to the conventional mortar matrix. (2) Increasing the fiber embedment length and the fiber volume fraction in the cement matrix increase the peak pullout load ...

1997-06-01

62

No short-term effects of digital mobile radio telephone on the awake human electroencephalogram  

Energy Technology Data Exchange (ETDEWEB)

A recent study reported the results of an exploratory study of alterations of the quantitative sleep profile due to the effects of a digital mobile radio telephone. Rapid eye movement (REM) was suppressed, and the spectral power density in the 8--13 Hz frequency range during REM sleep was altered. The aim of the present study was to illuminate the influence of digital mobile radio telephone on the awake electroencephalogram (EEG) of healthy subjects. For this purpose, the authors investigated 34 male subjects in a single-blind cross-over design experiment by measuring spontaneous EEGs under closed-eyes condition from scalp positions C{sub 3} and C{sub 4} and comparing the effects of an active and an inactive digital mobile radio telephone (GSM) system. During exposure of nearly 3.5 min to the 900 MHz electromagnetic field pulsed at a frequency of 217 Hz and with a pulse width of 580 {micro}s, the authors could not detect any difference in the ...

1997-05-01

63

Near-infrared photodetectors based on mercury indium telluride single crystals  

Science.gov (United States)

Attempt to form the Schottky barrier on mercury indium telluride (MIT) surface by deposition transparent conducting electrode (TCE) and avoid the negative results by non-rectifier contacts nature, we have investigated the oxidation of clean MIT surfaces to form an insulating layer to overcome this disadvantage by metal-insulator-semiconductor (MIS) photodetectors designing. Oxide film is grown on the MIT surface by plasma enhance chemical vapor deposition (PECVD). Previously cleaned MIT wafers were dipped and boiled in solution, which consists of mixture of bromine and an organic solvent in ratio of 1:50. By the way of using these films as intermediate slightly conducting insulator, a fast-response MIT based surface-barrier photodetectors have been developed. Pt films were used as TCE frontal electrode by vacuum magnetron sputtering (VMS). The current-voltage characteristic is described quantitatively based on the energy diagram and the found parameters of the ...

2008-03-01

64

Moderately heavy, heavy-fermion compound YbPd_2Si_2 at low temperatures  

International Nuclear Information System (INIS)

The available experimental data on the specific heat, magnetic susceptibility, magnetization, valence, NMR Knight shift and relaxation rate, and the quadrupolar moment of YbPd_2Si_2 are examined within the framework of the single-ion Anderson model. Such an analysis has previously given excellent agreement between theory and experiment for numerous other light heavy-fermion compounds, where crystalline fields do not play a dominant role. For YbPd_2Si_2, substantial crystalline-field splittings make difficult a quantitative comparison with existing exact solutions of the Anderson model. Inconsistencies with the interpretation that a nearly degenerate ground quadruplet determines the low-temperature thermodynamics are pointed out. It is concluded that at least three of the four Kramers doublets participate in the low-T properties. These three doublets should have a splitting of the order of the Kondo temperature, i.e., about 100 K. A simple ...

65

Moderately heavy, heavy-fermion compound YbPd sub 2 Si sub 2 at low temperatures  

Energy Technology Data Exchange (ETDEWEB)

The available experimental data on the specific heat, magnetic susceptibility, magnetization, valence, NMR Knight shift and relaxation rate, and the quadrupolar moment of YbPd{sub 2}Si{sub 2} are examined within the framework of the single-ion Anderson model. Such an analysis has previously given excellent agreement between theory and experiment for numerous other light heavy-fermion compounds, where crystalline fields do not play a dominant role. For YbPd{sub 2}Si{sub 2}, substantial crystalline-field splittings make difficult a quantitative comparison with existing exact solutions of the Anderson model. Inconsistencies with the interpretation that a nearly degenerate ground quadruplet determines the low-temperature thermodynamics are pointed out. It is concluded that at least three of the four Kramers doublets participate in the low-{ital T} properties. These three doublets should have a splitting of the order of the Kondo temperature, i.e., ...

1992-07-01

66

Fusion of Nonionic Vesicles  

DEFF Research Database (Denmark)

We present an experimental study of vesicle fusion using light and neutron scattering to monitor fusion events. Vesicles are reproducibly formed with an extrusion procedure using an single amphiphile triethylene glycol mono-n-decyl ether in water. They show long-term stability for temperatures around 20 C, but at temperatures above 26 C we observe an increase in the scattered intensity due to fusion. The system is unusually well suited for the study of basic mechanisms of vesicle fusion. The vesicles are flexible with a bending rigidity of only a few k(H)T. The monolayer spontaneous curvature, Ho, depends strongly on temperature in a known way and is thus tunable. For temperatures where H-0 > 0 vesicles tyre long-term stable, while in the range H-0 < 0 the fusion rate increases the more negative the Spontaneous curvature Through a quantitative;analysis of the fusion rate we arrive tit a barrier to fusion changing from 15 k(B)T at T = 26 ...

2010-01-01

67

Evidence of minimal methanogenic numbers and activity in sediments collected from the JAPEX/JNOC/GSC et al. Mallik 5L-38 gas hydrate production research well  

Energy Technology Data Exchange (ETDEWEB)

Gene analysis was used to determined the presence, abundance and phylogenetic affiliation of methanogens that exist in gas-hydrate-bearing sediment samples obtained from 23 drill cores from the JAPEX/JNOC/GSC et al. Mallik 5L-38 gas hydrate research well. Rates of methane production were examined using sediment-inoculated enrichments containing {sup 14}C-labeled carbon substrates, carbon dioxide and acetate. Archaeal 16S rDNA was only detected in 6 of the samples, resulting in 8 sequences with relationships to the Miscellaneous Crenarchaeotic Group (7 clones) and the Subsurface Euryarchaeotic Group (1 clone). The single Euryarchaeota sequence did not appear to be related to methanogens. Subsamples from the cores showed variable results upon DNA extraction and amplification. Methanogenic Coenzyme M (CoM) was detected in 13 of the 20 cores, but methanogenic methyl CoM reductase genes were not amplified from the samples when using a sensitive ...

2005-07-01

68

The (--)(/sup 3/H)dihydroalprenolol binding to rat adipocyte membranes: an explanation of curvilinear Scatchard plots and implications for quantitation of beta-adrenergic sites  

Energy Technology Data Exchange (ETDEWEB)

In rat adipocyte membranes, both beta-adrenergic agonists and beta-adrenergic antagonists competed with (--)(/sup 3/H)dihydroalprenolol for high affinity (KD 2-4 nM) and low capacity binding sites. The antagonists but not the agonists competed with (--)(/sup 3/H)dihydroalprenolol for lower affinity and higher capacity sites. The present studies were performed in order to characterize the adipocyte beta-adrenergic receptor and distinguish it from low affinity, higher capacity sites which were heat-labile and not stereoselective. When isoproterenol was used to define the nonspecific binding, saturation studies showed a single binding site with a capacity of approximately 100 fmol/mg membrane protein (corresponding to approximately 50,000 sites/adipocyte). Binding was saturated by 10 nM (--)(/sup 3/H)dihydroalprenolol. Approximate KD's of 204 nM were observed. Kinetic analysis of (--)(/sup 3/H)dihydroalprenolol binding provided an independent measurement of ...

1982-09-01

69

I-131 labelled peanut lectin renal kinetics in cis-platin induced tubular toxicity in dogs  

International Nuclear Information System (INIS)

Quantitative I-131 labelled Peanut lectin (I-131-PNA) renal clearance was determined in dogs before and after a 5 day single cycle cis-platinum chemotherapy regimen (0.5mg/Kg/day). Results were statistically compared with E.R.P.F. (I-131-Hippuran), G.F.R. (Tc-99m-DTPA), and serum biochemistry and correlated with histopathology. I-131-PNA clearance was significantly reduced in all dogs 5 days after cessation of cis-platinum treatment (mean #DELTA#S% = 71.3%) and similar reductions in the gamma camera derived renogram peak were demonstrated (mean #DELTA#S% = 65.8%). E.R.P.F. was noted to drop by a minor degree (mean #DELTA#S% = 20.9%) post treatment. G.F.R. was diminished (mean #DELTA#S% = 46.6%) and serum creatinine elevated (mean #DELTA#S% = 42.7%) in all dogs compared to their pretreatment values. Histopathology demonstrated variable degrees of tubular toxicity ranging from mild to severe. The degree of change of the I-131-PNA values was ...

1985-06-02

70

Effect of repeated benzene inhalation exposures on benzene metabolism, binding to hemoglobin, and induction of micronuclei  

International Nuclear Information System (INIS)

Metabolism of benzene is thought to be necessary to produce the toxic effects, including carcinogenicity, associated with benzene exposure. To extrapolate from the results of rodent studies to potential health risks in man, one must know how benzene metabolism is affected by species, dose, dose rate, and repeated versus single exposures. The purpose of our studies was to determine the effect of repeated inhalation exposures on the metabolism of [14C]benzene by rodents. Benzene metabolism was assessed by characterizing and quantitating urinary metabolites, and by quantitating 14C bound to hemoglobin and micronuclei induction. F344/N rats and B6C3F1 mice were exposed, nose-only, to 600 ppm benzene or to air (control) for 6 hr/day, 5 days/week for 3 weeks. On the last day, both benzene-pretreated and control animals were exposed to 600 ppm, 14C-labeled benzene for 6 hr. Individual benzene metabolites in urine collected for 24 ...

71

Computerized Tomography versus unenhanced and enhanced fast MRI sequences in the study of liver metastases: Qualitative and quantitative analyses  

International Nuclear Information System (INIS)

The authors compared unenhanced and contrast-enhanced fast MRI and Computerized Tomography in the detection of liver metastases. Eleven patients with single or multiple hepatic lesions (42 in all) were submitted to V and magnetic resonance studies; T1- and T2- weighted TSE, T2-weighted TSE with fat suppression, unenhanced breath-hold TFE and early or delayed enhanced breath-hold TFE images were acquired with a 1.5 T superconductive magnet (Philips NT). The quantitative analysis of all magnetic resonance images was performed for contrast/noise ratio (CNR) and number of detected lesions; magnetic resonance and Computerized Tomography images were also compared qualitatively for lesion conspicuity, anatomical structure identification and artifacts. The results were compared with Student's test. Early enhanced breath-hold TFE was statistically superior to T1-weighted TSE (p = .0009), T2-weighted TSE (p = .01) and Computerized Tomography ( p = .0004) ...

1997-01-01

72

A study on the mineral density of the lumbar vertebral bone in children of metabolic disorders and control using single energy quantitative CT  

Energy Technology Data Exchange (ETDEWEB)

A cross sectional study on the mineral density of the 3rd lumbar vertebral trabecular bone was carried out in 123 children less than 15 years old, comprising 44 controls, and 79 patients affected with conditions which are at risk for developing metabolic derangement of skeletal bone (34 patients taking antiepileptic drugs (AED), 29 undergoing glucocorticoid (GC) therapy and 16 bedridden patients), by using quantitative computed tomography (QCT) with a CaCO{sub 3} phantom. Serum Ca and alkaline-phosphatase (Alp) levels were measured at the time of QCT examinations in all. The results obtained were as follows: The QCT values in the control children showed neither age dependency nor a sexual difference before puberty. The QCT values in each group showed significant difference with one another; the control group>the AED group>the GC group>the bedridden group (p<0.05{approx}0.005). The serum Ca levels in each pathology group were significantly lower than ...

1991-06-01

79
80

Modelling of multifrequency IRMPD for laser isotope separation  

International Nuclear Information System (INIS)

The process of infrared multiple photon dissociation (IRMPD) of molecules is of great fundamental importance and has practical significance, such as isotope separation etc. Unfortunately, a clear insight into the process has been hindered by the bewildering array of important variables affecting MPD. The dissociation probability #gamma#(#phi#) i.e. the yield has been found to be a sensitive function of laser fluence #phi# along with numerous other parameters like laser frequency, gas pressure etc. We have shown that in single frequency IRMPD an accurate quantitative characterization of the dissociation probability can be adequately expressed by a 'power law' model with two fitting parameters namely critical fluence, #phi#c and multi photon order, m. This model was exploited in analysing our MPD results on various systems. However, the small isotope shift encountered in heavy elements and the sticking phenomenon observed in small light molecules ...

2002-12-01

81

Microscopic properties of passive films on Ti and Zr from optical, electrochemical and SXM-measurements  

International Nuclear Information System (INIS)

A combined application of several microtechniques is presented and discussed with the Ti/TiO_2 and Zr/ZrO_2-systems as an example. All measurements were carried out on single grains of technical materials in order to detect and quantify the effect of substrate microstructure on the properties of anodic passive films formed potentiodynamically in 0.5 M H_2SO_4 (dU/dt = 20 mVs"-"1). Anisotropy-micro-ellipsometry (AME) was employed to determine the crystallographic orientation of the substrate grains along with passive film thickness and crystallinity in dependence on the anodization potential. Both the isotropic (amorphous) TiO_2- and the anisotropic (crystalline) ZrO_2-films exhibit a systematic dependence of film thickness on the grain orientation. Local LASER-scanning photocurrent measurements (#lambda#=257 nm) on the same grains likewise show a heterogeneity of the photoelectrochemical reactivity in all cases. This is quantitatively explained ...

1998-03-01

82

Growth and cell kinetic changes of HeLa S-3 spheroids following hyperfractionated irradiation  

International Nuclear Information System (INIS)

Optimal design of the hyperfractionated radiotherapy requires basic radiobiological data such as the critical dose per fraction, number of fractions per day and total equivalent dose, to name a few. As a prelude to in vivo hyperfractionated irradiation, the authors carried out experiments to determine quantitative changes in the proliferation and cell kinetic parameters of multicellular spheroids after hyperfractionated irradiation. Experiments were carried out with HeLa S-3 spheroid growing in MEM culture media. Hyperfractionated irradiation schedules were 1.5 Gy/f, 2f/day and 1.0 Gy/f, 3 f/day. At intervals after irradiation, cell numbers, growth delays and cell cycle distribution of spheroids were determined. The kinetic data were obtained by the use of flow cytometry. The most pronounced changes in cell kinetic parameters were early G/sub 2/M block, proportional to single radiation dose up to 4.0 Gy. There was a corresponding depletion of ...

84

Quantitative CT assessment of proximal femoral bone density. An experimental study concerning its correlation to breaking load for femoral neck fractures; Quantitative CT des proximalen Femurs. Experimentelle Untersuchungen zur Korrelation mit der Bruchlast bei Schenkelhalsfrakturen  

Energy Technology Data Exchange (ETDEWEB)

Purpose: In an experimental study, the correlation between the trabecular bone density of the different regions of the proximal femur and the fracture load in the setting of femoral neck fractures was examined. Methods: The bone mineral density 41 random proximal human femora was estimated by single-energy quanitative CT (SE-QCT). The trabecular bone density was measured at the greatest possible extracortical volume at midcapital, midneck and intertrochanteric level and in the 1 cm{sup 3} volumes of the centres of these regions in a standardised 10 mm thick slice in the middle of the femoral neck axis (in mg/ml Ca-hydroxyl apatite). The proximal femora were then isolated and mounted on a compression/bending device under two-legged stand conditions and loaded up to the point when a femoral neck fracture occurred. Results: Statistical analysis revealed a linear correlation between the trabecular bone density and the fracture load for the greater regions, with the ...

1997-12-01

85

Contaminant transport in fracture networks with heterogeneous rock matrices. The Picnic code  

Energy Technology Data Exchange (ETDEWEB)

In the context of safety assessment of radioactive waste repositories, complex radionuclide transport models covering key safety-relevant processes play a major role. In recent Swiss safety assessments, such as Kristallin-I, an important drawback was the limitation in geosphere modelling capability to account for geosphere heterogeneities. In marked contrast to this limitation in modelling capabilities, great effort has been put into investigating the heterogeneity of the geosphere as it impacts on hydrology. Structural geological methods have been used to look at the geometry of the flow paths on a small scale and the diffusion and sorption properties of different rock materials have been investigated. This huge amount of information could however be only partially applied in geosphere transport modelling. To make use of these investigations the 'PICNIC project' was established as a joint cooperation of PSI/Nagra and QuantiSci to provide a new geosphere transport ...

2001-02-01

86

Role of Quantitative Bone Scanning in the Assessment of Bone Turnover in Patients With Charcot Foot  

UK PubMed Central (United Kingdom)

OBJECTIVETo assess the new quantitative bone scan parameters as markers of Charcot neuroosteoarthropathy (CNO) activity.RESEARCH DESIGN AND METHODSForty-two...Full Text Available

2010-02-01

87

Quantitative structure-activity relationships of insecticides and plant growth regulators: comparative studies toward understanding the molecular mechanism of action.  

UK PubMed Central (United Kingdom)

Emphasis was put on the comparative quantitative structure-activity approaches to the exploration of action mechanisms of structurally different classes of compounds showing the same type of activity...Full Text Available

1985-09-01

88

Quantitative evaluation of siRNA delivery in vivo  

UK PubMed Central (United Kingdom)

Effective small interfering RNA (siRNA)–mediated therapeutics require the siRNA to be delivered into the cellular RNA-induced silencing complex (RISC). Quantitative information of this essential...Full Text Available

2010-12-01

89

Mapping Quantitative Trait Loci Controlling Milk Production in Dairy Cattle by Exploiting Progeny Testing  

UK PubMed Central (United Kingdom)

We have exploited ``progeny testing'' to map quantitative trait loci (QTL) underlying the genetic variation of milk production in a selected dairy cattle population. A total of 1,518 sires, with progeny...Full Text Available

1995-02-01

90

From Classical Genetics to Quantitative Genetics to Systems Biology: Modeling Epistasis  

UK PubMed Central (United Kingdom)

Gene expression data has been used in lieu of phenotype in both classical and quantitative genetic settings. These two disciplines have separate approaches to measuring and interpreting epistasis, which...Full Text Available

2008-03-01

91

Fabp7 Maps to a Quantitative Trait Locus for a Schizophrenia Endophenotype  

UK PubMed Central (United Kingdom)

Deficits in prepulse inhibition (PPI) are a biological marker for schizophrenia. To unravel the mechanisms that control PPI, we performed quantitative trait loci (QTL) analysis on 1,010 F2 mice derived...Full Text Available

2007-11-01

92

Evaluation of the ERETIC Method as an Improved Quantitative Reference for 1H HR-MAS Spectroscopy of Prostate Tissue  

UK PubMed Central (United Kingdom)

The Electronic REference To access In vivo Concentrations (ERETIC) method was applied to 1H HR-MAS spectroscopy. The accuracy, precision, and stability of ERETIC as a quantitative...Full Text Available

2009-03-01

93

SIMV: An Application of Mathematical Modeling in Ventilator Management  

UK PubMed Central (United Kingdom)

SIMV (simulation and modeling of ventilation) is a quantitative system for the mathematical modeling and simulation of pulmonary...Full Text Available

1989-11-08

95

Interest of quantitative bone scintigraphy  

International Nuclear Information System (INIS)

French 1979. p. 4.35-4.48. France Granier, R. Bittoun, J. Doury, P. Pattin,

99

Quantitative phase imaging using hard x-rays  

International Nuclear Information System (INIS)

The quantitative imaging of a phase object using 16 keV x-rays is reported. The theoretical basis of the techniques is presented along with its implementation using a synchrotron x-ray source. It is found that the phase image is in quantitative agreement with independent measurements of the object. 13 refs., 5 figs.

2009-02-01

102

Substitution of old single flat gas heating systems: Comparision of modernization possibilities; Ersatz alter Gasetagenheizungen: Vergleich von Modernisierungsvarianten  

Energy Technology Data Exchange (ETDEWEB)

The research project's objective is to create a decision help for owners of residential buildings for several families regarding the renewal of decentralized heating and warm water preparation systems in the flats. The focus lies on a comparison of the costs of typical systems on the basis of a full cost calculation. This is done by taking into consideration the intentions of residential building companies like the reduction of additional costs to be paid by the tenants (both for social reasons and to make the flats easier to rent), low investment costs, low maintenance costs, energy saving, tenants' claims for comfort and acceptance by the tenants, economical reasons, especially regarding flats fully amortized (activation in the balance sheet). In addition to the quantitative comparison, the advantages and disadvantages of the different systems were also compared to one another from the qualitative point of view. [German] Ziel des ...

2004-04-01

103

Study of the effect of noncondensable gas on heat transfer phenomena in horizontal steam generator of pactel facility with CATHARE2 V1.5a  

International Nuclear Information System (INIS)

Lappeenranta University of Technology (LTKK) and VTT Energy carried out a series of preliminary tests in 1999 to study the behavior of noncondensable (NC) gases in VVER geometry. The tests aimed at studying the effect of NC gases on system thermal-hydraulics and on heat transfer in a horizontal steam generator (HSG). The system behavior can be affected by hydrogen produced in the core in case of a severe accident, by nitrogen from hydro-accumulators released into the primary circuit in case of a loss-of-coolant accident (LOCA) and more generally by any NC gas in all cases where cooling is ensured by natural circulation. A secondary objective of the tests - the first series of tests ever performed with NC gas with PACTEL - was to find out, if the instrumentation of PACTEL was adequate for this type of tests and if it was functioning properly. This paper presents the measured and calculated (CATHARE code version V15a mod 2.1) results of the test NCg-l. It was carried out in natural ...

2001-03-20

104

Pre-therapy 18F-FDG PET quantitative parameters help in predicting the response to radioimmunotherapy in non-Hodgkin lymphoma  

International Nuclear Information System (INIS)

Radioimmunotherapy (RIT) is a new treatment option for patients with non-Hodgkin lymphoma (NHL). Response to RIT currently remains difficult to predict using conventional prognostic factors and could be refined using functional imaging. The goal of this work is to evaluate the value of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) in predicting response to Yttrium 90-labeled monoclonal antibodies for patients with NHL. Thirty-five patients with NHL who had undergone 18F-FDG PET prior to RIT with either 90Y-ibritumomab tiuxetan (group A; n=17) or 90Y-epratuzumab tetraxetan (group B; n=18) were included in this retrospective study. Four functional criteria were determined for each tumour lesion in a given patient: maximum and mean standard uptake values (SUVmax and SUVmean), functional lesion volume (LVol) and total lesion glycolysis (TLG, product of the volume and the SUVmean). For each patient, we determined highest SUVmax and SUVmean, cumulative TLG (TLGcum) and sum ...

2010-03-01

105

Magnetic field exposure assessment for adult residents of Maine who live near and far away from overhead transmission lines  

Science.gov (United States)

Sixty-Hz magnetic field exposures were measured for 45 adult residents of Maine. Thirty of the subjects resided near rights-of-way (ROWs) with either 345- and 115-kV transmission lines, or ROWs with only 115-kV transmission lines; fifteen resided far from any transmission lines. Personal exposure data for a single 24-hour period was acquired with the EMDEX. The EMDEX's event-marker button was used to partition exposures into Home and Away components. Also, three area measurements were taken for each subject during the personal exposure measurement period: (1) 24-hr fixed-site bedroom measurement with a second EMDEX; (2) Spot measurements in at least three rooms of every residence; and (3) Spot measurements outside each residence. Residence near transmission lines highly loaded during the measurement period was associated with increased Home and Total exposure relative to a far-away population. Average exposure level while away from home was uniform (at ...

1992-01-01

106

Kinetic analysis of transport and opioid receptor binding of ( sup 3 H)(-)-cyclofoxy in rat brain in vivo: Implications for human studies  

Energy Technology Data Exchange (ETDEWEB)

(3H)Cyclofoxy (CF: 17-cyclopropylmethyl-3,14-dihydroxy-4,5-alpha-epoxy-6-beta-fluoromorp hinan) is an opioid antagonist with affinity to both mu and kappa subtypes that was synthesized for quantitative evaluation of opioid receptor binding in vivo. Two sets of experiments in rats were analyzed. The first involved determining the metabolite-corrected blood concentration and tissue distribution of CF in brain 1 to 60 min after i.v. bolus injection. The second involved measuring brain washout for 15 to 120 s following intracarotid artery injection of CF. A physiologically based model and a classical compartmental pharmacokinetic model were compared. The models included different assumptions for transport across the blood-brain barrier (BBB); estimates of nonspecific tissue binding and specific binding to a single opiate receptor site were found to be essentially the same with both models. The nonspecific binding equilibrium constant varied ...

1991-03-01

107

Human exposure to PCDDs, PCDFs, and dioxin like PCBs in Japan, 2001  

Energy Technology Data Exchange (ETDEWEB)

In our previous study, we have estimated the level of human exposure to dioxins (PCDDs, PCDFs, and Dioxin like PCBs) in Japan based on dioxins monitoring data and results of total diet studies (TDS) in fiscal 2000 (April 2000- March 2001). It has been reported that the national PCDDs/DFs emission in 2001 against the 1997 level has been reduced by approximately 77% In addition, reduction of environmental levels was reported. The enforcement of Japan's Law Concerning Special Measures against Dioxins has significant impact on the reduction of the average dioxins concentrations in the ambient air. Therefore, the transitions of Japanese dioxins exposure levels in recent years are worthy of attention. In order to determine exposure level in fiscal 2001, collection and compilation for surveillance results derived from the regular environmental monitoring under the law as well as other dioxins surveys by national and local governmental bodies were continued, and the data were ...

2004-09-15

108

Heat transfer characteristics of horizontal steam generators under natural circulation conditions  

Energy Technology Data Exchange (ETDEWEB)

This paper deals with the heat transfer characteristics of horizontal steam generators, particularly under natural circulation (decay heat removal) conditions on the primary side. Special emphasis is on the inherent features of horizontal steam generator behaviour. A mathematical model of the horizontal steam generator primary side is developed and qualitative results are obtained analytically. A computer code, called HSG, is developed to solve the model numerically, and its predictions are compared with experimental data. The code is employed to obtain for VVER 440 steam generators quantitative results concerning the dependence of primary-to-secondary heat transfer efficiency on the primary side flow rate, temperature and secondary level. It turns out that the depletion of the secondary inventory leads to an inherent limitation of the decay energy removal in VVER steam generators. The limitation arises as a consequence of the steam generator tube bundle geometry. ...

1996-10-01

109

Genetic analysis of carbon isotope discrimination and its relation to yield in a wheat doubled haploid population.  

Science.gov (United States)

Carbon isotope discrimination (?(13) C) is considered a useful indicator for indirect selection of grain yield (GY) in cereals. Therefore, it is important to evaluate the genetic variation in ?(13) C and its relationship with GY. A doubled haploid (DH) population derived from a cross of two common wheat varieties, Hanxuan 10 (H10) and Lumai 14 (L14), was phenotyped for ?(13) C in the flag leaf, GY and yield associated traits in two trials contrasted by water availability, specifically, rain-fed and irrigated. Quantitative trait loci (QTLs) were identified by single locus and two locus QTL analyses. QTLs for ?(13) C were located on chromosomes 1A, 2B, 3B, 5A, 7A and 7B, and QTLs for other traits on all chromosomes except 1A, 4D, 5A, 5B and 6D. The population selected for high ?(13) C had an increased frequency of QTL for high ?(13) C, GY and number of spikes per plant (NSP) when grown under rain-fed conditions and only for high ?(13) C and NSP ...

2011-09-01

110

Dopamine transporter density in the basal ganglia assessed with [{sup 123}I]IPT SPET in children with attention deficit hyperactivity disorder  

Energy Technology Data Exchange (ETDEWEB)

Attention deficit hyperactivity disorder (ADHD) is a psychiatric disorder in childhood that is known to be associated with dopamine dysregulation. In this study, we investigated dopamine transporter (DAT) density in children with ADHD using iodine-123 labelled N-(3-iodopropen-2-yl)-2&beta;-carbomethoxy-3&beta;-(4-chlorophenyl) tropane ([{sup 123}I]IPT) single-photon emission tomography (SPET) and postulated that an alteration in DAT density in the basal ganglia is responsible for dopaminergic dysfunction in children with ADHD. Nine drug-naive children with ADHD and six normal children were included in the study. We performed brain SPET 2 h after the intravenous administration of [{sup 123}I]IPT and carried out both quantitative and qualitative analyses using the obtained SPET data, which were reconstructed for the assessment of the specific/non-specific DAT binding ratio in the basal ganglia. We then investigated the correlation ...

2003-02-01

111

Calculation of the output power in self-amplified spontaneous radiation using scaling of power with number of simulation particles  

International Nuclear Information System (INIS)

Recent advances in self-amplified spontaneous emission (SASE) experiments stimulate interest in quantitative comparison of measurements with theory. In this paper we show that the widely used simulation code TDA3D, developed by Tran and Wurtele [Comput. Phys. Commun. 54, 263 (1989)] even though a single frequency code, can be used to determine the output power in the SASE process with excellent approximation in the exponential growth regime. The method applies when the gain is not very high, which is a special advantage, because when the gain is not very high, the analytical calculation is particularly difficult since the exponential growing term does not dominate. The analysis utilizes a scaling relation between the output power and the number of simulation particles in the code TDA3D: left-angle P right-angle=N_#lambda#"'/N_#lambda# left-angle P"'right-angle, where left-angle P right-angle is the output power and N_#lambda# is the line ...

1998-10-01

112

Biological assessments of a mixture of endocrine disruptors at environmentally relevant concentrations in water following UV/H{sub 2}O{sub 2} oxidation  

Energy Technology Data Exchange (ETDEWEB)

Numerous studies have investigated degradation of individual endocrine disrupting compounds (EDCs) in lab or natural waters. However, natural variations in water matrices and mixtures of EDCs in the environment may confound analysis of the treatment efficiency. Because chemical based analytical methods cannot represent the combined or synergistic activities between water quality parameters and/or the EDC mixtures at environmentally relevant concentrations ({mu}g L{sup -1}-ng L{sup -1}), bioanalytical assessments of residual estrogenic activity in treated water were used to evaluate the performance of the UV based advanced oxidation process for estrogenic contaminants in water. Four EDCs including estradiol (E{sub 2}), ethinyl estradiol (EE{sub 2}), bisphenol-A (BPA) and nonylphenol (NP) were spiked individually or as a mixture at {mu}g L{sup -1}-ng L{sup -1} in laboratory or natural river water. The removal rates of estrogenic activity were quantitatively evaluated ...

2007-04-15

113

Attention deficit hyperactivity disorder: binding of [{sup 99m}Tc]TRODAT-1 to the dopamine transporter before and after methylphenidate treatment  

Energy Technology Data Exchange (ETDEWEB)

Involvement of the dopaminergic system has been suggested in patients suffering from attention deficit hyperactivity disorder (ADHD) since the symptoms can be successfully treated with methylphenidate, a potent blocker of the dopamine transporter (DAT). This study reports the findings on the status of the DAT in adults with ADHD before and after commencement of treatment with methylphenidate, as measured using [{sup 99m}Tc]TRODAT-1. Seventeen patients (seven males, ten females, aged 21-64 years, mean 38 years) were examined before and after the initiation of methylphenidate treatment (3 x 5 mg/day). All subjects were injected with 800 MBq [{sup 99m}Tc]TRODAT-1 and imaged 3 h p.i. Single-photon emission tomography (SPET) scans were acquired using a triple-headed gamma camera. For semi-quantitative evaluation of the DAT, transverse slices corrected for attenuation were used to calculate specific binding in the striatum, with the cerebellum used ...

2000-10-01

114

A Wheat Homolog of MOTHER OF FT AND TFL1 Acts in the Regulation of Germination.  

Science.gov (United States)

Seed dormancy is an adaptive mechanism and an important agronomic trait. Temperature during seed development strongly affects seed dormancy in wheat (Triticum aestivum) with lower temperatures producing higher levels of seed dormancy. To identify genes important for seed dormancy, we used a wheat microarray to analyze gene expression in embryos from mature seeds grown at lower and higher temperatures. We found that a wheat homolog of MOTHER OF FT AND TFL1 (MFT) was upregulated after physiological maturity in dormant seeds grown at the lower temperature. In situ hybridization analysis indicated that MFT was exclusively expressed in the scutellum and coleorhiza. Mapping analysis showed that MFT on chromosome 3A (MFT-3A) colocalized with the seed dormancy quantitative trait locus (QTL) QPhs.ocs-3A.1. MFT-3A expression levels in a dormant cultivar used for the detection of the QTL were higher after physiological maturity; this increased expression correlated with a ...

2011-09-01

115

A Simulation Study on a Radioactive Nuclide's Distribution within a Fuel rod by a Tomographic Gamma Scanning  

Energy Technology Data Exchange (ETDEWEB)

Gamma scanning measurements are used to determine the radioactive nuclides from an irradiated fuel rod in a hot cell which is a routine task in the Irradiated Materials Examination Facility (IMEF) of the Korea Atomic Energy Research Institute (KAERI), Total gamma spectra of radioactive nuclides and the atomic ratio of {sup 134}Cs to {sup 137}Cs in a few segments of a single fuel rod are measured by the present gamma scanning system. For the purpose of determining the radioactive nuclide's distribution in detail within a fuel rod quantitatively, we attempt to upgrade the present gamma scanning system in this paper, therefore, an investigation of the feasibility of the tomographic gamma scanning (TGS) technique, which is one of the promising nondestructive assay (NDA) methods is proposed. The TGS technique is an efficient method and it has an accurate precision for the characterization of several fuel parameters. In this paper, a ...

2006-07-01

116

Quantitative dissolution of (U, Pu)O_2 MOX (0.4% to 44% PuO_2) using microwave heating technique  

International Nuclear Information System (INIS)

AFFF has fabricated the (U, Pu)O_2 mixed oxide fuels for PHWRs, BWRs, PFBRs and FBTRs. The quantitative dissolution of the fuel samples are required within time for accurate determination of uranium-plutonium in chemical quality control laboratory. This paper describes the use of microwave heating technique in quantitative dissolution of (U, Pu)O_2 MOX (from 0.4% to 44% PuO_2). (author)

2011-02-22

117

Wind and Wave Forcing of Longshore Currents Across a ...  

Science.gov (United States)

... These assumptions are quantitatively investigated by calculating tie icldti\\e inportance of ... A modified lon-shore current model is used to study the ...

1988-06-01

118

The interpretation of systematic reviews with meta-analyses: an objective or subjective process?  

UK PubMed Central (United Kingdom)

BackgroundDiscrepancies between the conclusions of different meta-analyses (quantitative syntheses of systematic reviews) are often ascribed to methodological differences. The objective...Full Text Available

119

STR Training Materials  

Science.gov (United States)

Typing Workshop": [Introductions] [Intro, DNA Basics, and Historical Perspective] [DNA Extraction] [Validation and QA/QC] [DNA Quantitation] [PCR Amplification] [STR Loci and Kits]...

2011-04-29

120

Quantitative morphology and water distribution of bronchial biopsy samples.  

UK PubMed Central (United Kingdom)

BACKGROUND: An approach to the study of the pharmacokinetics of drugs in the lung is to measure their concentrations in bronchial biopsy specimens. The main criticism of this technique is that bronchial...Full Text Available

1992-07-01

121

Quantitative investigation of the crowding effect of Hymenolepis diminuta in Rattus norvegicus  

Science.gov (United States)

This laboratory exercise demonstrates some basic principles in parasitology by using experimental studies of the relationship of Hymenolepis diminuta with its rodent host.

2000-01-01

122

Quantitative easing works: Lessons from the unique experience in Japan 2001-2006  

British Library Electronic Table of Contents (United Kingdom)

Abstract: The current financial crisis has now led most major central banks to rely on quantitative easing. The unique Japanese experience of quantitative easing is the only experience which enables us to judge this therapy's effectiveness and the timing of the exit strategy. In this paper, we provide a new empirical framework to examine the effectiveness of Japanese monetary policy during the ''lost'' decade and quantify the effect of quantitative easing on Japan's activity and prices. We combine advantages of Markov-switching VAR methodology with those of factor analysis to establish two major findings. First, we show that the decisive change in regime occurred in two steps: it crept out from late 1995 and established itself durably in February 1999. Second, we show for the first time th...

2011-01-01

123

Quantitative cerebral blood flow with Optical Coherence Tomography  

UK PubMed Central (United Kingdom)

Absolute measurements of cerebral blood flow (CBF) are an important endpoint in studies of cerebral pathophysiology. Currently no accepted method exists for in vivo longitudinal...Full Text Available

2010-02-01

124

Quantitative Spectroscopy of Photospheric-Phase Type II SN  

Science.gov (United States)

... and high-quality photospheric-phase Type II SN spectra to constrain core- collapse SN explosions, massive star evolution, and distances in the Universe ...

125

Preliminary exploration of online social support among adults with asthma  

UK PubMed Central (United Kingdom)

OBJECTIVEEvaluate the qualitative and quantitative differences between moderated and unmoderated on-line social support groups focused on asthma.DESIGNA...Full Text Available

2003-01-01

126

Prediction of Chemicals Ecotoxicity  

International Science & Technology Center (ISTC)

Computer-Aided Prediction of Chemical Ecotoxicity on the basis of Quantitative Structure-Activity Relationships with the Use of Physico-Chemical Descriptors, Including H-bond Parameters

128

Gallbladder function and dynamics of bile flow in asymptomatic gallstone disease  

UK PubMed Central (United Kingdom)

AIM: To investigate the effects of gallbladder stones on motor functions of the gallbladder and the dynamics of bile flow in asymptomatic gallstone disease.METHODS: Quantitative hepatobiliary...Full Text Available

2009-06-14

129

Fractal parameters and vascular networks: facts & artifacts  

UK PubMed Central (United Kingdom)

BackgroundSeveral fractal and non-fractal parameters have been considered for the quantitative assessment of the vascular architecture, using a variety of test specimens and of computational...Full Text Available

130

Condition Monitoring of Aircraft by Quantitative Filter Debris ...  

Science.gov (United States)

... 15- Two Sigma from Mean S..... I ..... 2 ... only a small number of engine filter debris samples ... comprehensive, but it does point out that ...

1996-04-01

131

Barriers to Initiating Depression Treatment in Primary Care Practice  

UK PubMed Central (United Kingdom)

OBJECTIVE AND DESIGNThis study used qualitative and quantitative methods to examine the reasons primary care physicians and nurses offered for their inability to initiate guideline-concordant...Full Text Available

2002-02-01

132

Apolipoproteins in rat serum and renal lymph.  

UK PubMed Central (United Kingdom)

The concentration of apolipoproteins was measured by quantitative immunoelectrophoresis in rat serum, in the lipoprotein-free ultracentrifugal fraction (density greater than 1.21) of serum, and in renal...Full Text Available

1976-05-01

133

A gravitational diffusion model without dark matter  

UK PubMed Central (United Kingdom)

In this model, without dark matter, the flat rotation curves of galaxies and the mass-to-light ratios of clusters of galaxies are described quantitatively. The hypothesis is that the agent of gravitational...Full Text Available

1998-03-31

134

Title of paper: the induction of P-53 independent programmed cell death (apoptosis) with ionizing radiation and 5-fluorouracil (5-FU) in the HT-29 human colon carcinoma cell line  

International Nuclear Information System (INIS)

Purpose/Objective: The role of programmed cell death (apoptosis) as a cellular response to cancer therapy such as radiation or chemotherapy is the subject of much study, and manipulation of the apoptotic response in tumor cells may be valuable in the treatment of a variety of cancers. Both p53 dependent and independent apoptotic pathways have been identified; p53 is mutated in at least 50 % of human cancers and a majority of radiation resistant tumors contain p53 mutations. This study is designed to examine the induction of programmed cell death in a human colon carcinoma cell line that possesses two mutated p53 alleles. Ionizing radiation alone, or in combination with the chemotherapeutic drug 5-fluorouracil (5-FU), were used to elicit the apoptotic response. This study will focus on whether these treatments can induce a significant apoptotic response in cells that have mutated p53 alleles. Materials and Methods: HT-29 cells were assessed for clonogenic survival after being plated at ...

1996-09-01

135

Simulation of sludge deposit onto a 900 MW steam generator tubesheet with the 3D code GENEPI  

Energy Technology Data Exchange (ETDEWEB)

Heat transfer processes use fluids which are generally not pure and can react with transfer surfaces. These surfaces are subject to deposits which can be sediments harmful to heat transfer and to integrity of materials. For nuclear plant steam generators, sludge build-up accelerates secondary side corrosion by concentrating chemical species. A major safety problem involved with such a corrosion is the growing of circumferential cracks which are very difficult to detect and size with eddy current probes. With a view to understand and control this problem, it is necessary to develop a mathematical model for the prediction of sludge behavior in PWR steam generators. Based on fundamental principles, this work intends to use different models available in literature for the prediction of the phenomenon leading to the accumulation of sludge particles at the bottom (the tubesheet) of a PWR. For that, a three-dimensional simulation of magnetite particulate fouling with the finite elements code ...

1998-07-01

136

In-situ measurement of epithelial tissue optical properties: Development and implementation of diffuse reflectance spectroscopy techniques  

Science.gov (United States)

Cancer is a severe threat to human health. Early detection is considered the best way to increase the chance for survival. While the traditional cancer detection method, biopsy, is invasive, noninvasive optical diagnostic techniques are revolutionizing the way that cancer is diagnosed. Reflectance spectroscopy is one of these optical spectroscopy techniques showing promise as a diagnostic tool for pre-cancer detection. When a neoplasia occurs in tissue, morphologic and biochemical changes happen in the tissue, which in turn results in the change of optical properties and reflectance spectroscopy. Therefore, a pre-cancer can be detected by extracting optical properties from reflectance spectroscopy. This dissertation described the construction of a fiberoptic based reflectance system and the development of a series of modeling studies. This research is aimed at establishing an improved understanding of the optical properties of mucosal tissues by analyzing reflectance signals at ...

2009-01-01

137

Cellular Sources of Transforming Growth Factor-? Isoforms in Early and Chronic Radiation Enteropathy  

Science.gov (United States)

The three mammalian transforming growth factor (TGF)-? isoforms (TGF-?1, TGF-?2, and TGF-?3) differ in their putative roles in radiation-induced fibrosis in intestine and other organs. Furthermore, tissue specificity of TGF-? action may result from temporal or spatial changes in production and/or activation. The present study examined shifts in the cell types expressing TGF-? mRNA relative to TGF-? immunoreactivity and histopathological injury during radiation enteropathy development. A 4-cm loop of rat small intestine was locally exposed to 0, 12, or 21-Gy single doses of x-irradiation. Sham-irradiated and irradiated intestine were procured 2 and 26 weeks after irradiation. Cells expressing the TGF-?1, TGF-?2, or TGF-?3 transcripts were identified by in situ hybridization with digoxigenin-labeled riboprobes. Intestinal wall TGF-? immunoreactivity was measured using computerized image analysis, and structural radiation injury was assessed by ...

1998-11-01

138

Unraveling electronic energy transfer in single conjugated polyelectrolytes encapsulated in lipid vesicles  

UK PubMed Central (United Kingdom)

A method for the study of conjugated polyelectrolyte (CPE) photophysics in solution at the single-molecule level is described. Extended observation times of single polymer molecules are enabled by the...Full Text Available

2010-10-12

139

Single leptoquark production at [ital e][sup +][ital e[minus  

Energy Technology Data Exchange (ETDEWEB)

We consider single production of leptoquarks (LQ's) at [ital e][sup +][ital e[minus

1994-04-01

140

Single Manager for DOD Military Working Dog Program.  

Science.gov (United States)

The Directive establishes a single manager for the Department of Defense Military Working Dog Program, provides policy, prescribes procedures, and assigns responsibilities.

1983-01-01

141

SOLID STATE RESEARCH OF THE APPLIED PHYSICS ...  

Science.gov (United States)

... 10 TIN TELLURIDE Preparation of Tin Telluride Single Crystals ..... 12 ... TIN TELLURIDE Preparation of Tin Telluride Single Crystals ...

1962-07-16

142

Tracing Cadmium from Culture to Spikelet: Noninvasive Imaging and Quantitative Characterization of Absorption, Transport, and Accumulation of Cadmium in an Intact Rice Plant1[W][OA]  

UK PubMed Central (United Kingdom)

We characterized the absorption and short-term translocation of cadmium (Cd) in rice (Oryza sativa ‘Nipponbare’) quantitatively using serial images observed with a positron-emitting...Full Text Available

2010-04-01

143

Quantitative determination of atmospheric hydroperoxyl radical  

Energy Technology Data Exchange (ETDEWEB)

A method for the quantitative determination of atmospheric hydroperoxyl radical comprising: (a) contacting a liquid phase atmospheric sample with a chemiluminescent compound which luminesces on contact with hydroperoxyl radical; (b) determining luminescence intensity from the liquid phase atmospheric sample; and (c) comparing said luminescence intensity from the liquid phase atmospheric sample to a standard luminescence intensity for hydroperoxyl radical. An apparatus for automating the method is also included.

2007-10-23

144

Quantitation of Indoleacetic Acid Conjugates in Bean Seeds by Direct Tissue Hydrolysis 1  

UK PubMed Central (United Kingdom)

Gas chromatography-selected ion monitoring-mass spectral analysis using [13C6]indole-3-acetic acid (IAA) as an internal standard provides an effective means for quantitation of...Full Text Available

1989-06-01

145

Polymer depletion-induced slip near an interface  

Energy Technology Data Exchange (ETDEWEB)

A quantitative description is proposed for the depletion-induced slip thickness and velocity profile of a polymer solution near the wall-fluid interface in simple shear flow. The inhomogeneous polymer density profile at a flat wall is inserted into the equations of motion for the flow of a polymer solution near the flat wall. The theory is in quantitative agreement with simulation results. (letter to the editor)

2005-01-19

146

On the Field Dependent Surface Resistance Observed in Superconducting Niobium Cavities  

CERN Document Server

A quantitative description is presented of the non-linear current-voltage response in superconducting niobium cavities for accelerator application. It is based on a fit for a large sample of data from cavity tests of different kind. Trial functions for the surface resistance describing this non-linear relation are established by a least square data fit. Those trial functions yielding the best fit are quantitatively explained by basic physics.

2009-01-01

147

Mapping quantitative trait loci (QTL) in sheep. II. Meta-assembly and identification of novel QTL for milk production traits in sheep  

UK PubMed Central (United Kingdom)

An (Awassi × Merino) × Merino backcross family of 172 ewes was used to map quantitative trait loci (QTL) for different milk production traits on a framework map of 200 loci across all...Full Text Available

148

Localization of an anti-tumour monoclonal antibody in human tumour xenografts: kinetic and quantitative studies with the 791T/36 antibody  

International Nuclear Information System (INIS)

Studies have been performed with an anti-osteogenic sarcoma monoclonal antibody 791T/36 and human tumour xenografts to examine some of the quantitative and kinetic aspects of tumour localization. The influence of variations in tumour size and site and antibody dose on the extent and rate of specific antibody localization have been examined, together with the site of intratumoural deposition of the antibody. (UK).

149

An immunochemical approach to the study of DNA damage and repair  

Energy Technology Data Exchange (ETDEWEB)

The overall objective of this project is to produce antibodies to unique modified DNA bases and develop immunochemical assays to quantitate these lesions in damaged DNA. During this past year we have developed an antibody and chemical test to quantitate a basic sites in DNA and produced antibodies to the 8-oxopurines. This report discusses the detection of a basic sites in DNA and the preparation of antibodies to 8-hydroxyadenine and 8-hydroxyguanine.

1990-11-14

150

Quantitative bone scintigraphy in renal osteodystrophy  

International Nuclear Information System (INIS)

The need for noninvasive sensitive techniques for the diagnosis and follow-up of metabolic bone disease in dialysis patients has stimulated the author's interest in the efficacy of more detailed quantitative bone scintigraphy. Using hemodialysis to reduce elevated soft-tissue activity at scintigraphy, an attempt was made to assess the diagnostic sensitivity of quantitative bone scintigraphy as compared to qualitative bone scintigraphic, biochemical, radiographic and bone histologic studies. The second aim of these studies was to determine if one of the two major components of renal osteodystrophy is a major determinant for skeletal radiotracer uptake. The clinical observations on the efficacy and possible specificity of quantitative bone scintigraphy in the diagnosis and follow-up during treatment of renal osteodystrophy are presented briefly in this chapter. Thus, the use of scintigraphy for the routine detection and ...

160

Diquarks in gamma-p Collisions at LHeC  

CERN Document Server

This note studies the single production of scalar or vector diquarks at the LHeC collider.

2011-01-01

163

Single-pole switching schemes for EHV transmission systems  

Energy Technology Data Exchange (ETDEWEB)

Recognizing that a high percentage of transmission-line faults are single-phase to earth and temporary in nature, provides the impetus for considering single-pole switching as a means to enhance the reliability of EHV transmission systems. The effectiveness of single-pole switching schemes is largely determined by the speed with which the secondary arcs extinguish, and hence allow system restoration. Simulation techniques that enable better prediction of the faulted-system response are of obvious importance to the design and assessment of the various single-pole switching scheme applications. In this thesis, digital methods are developed to enable the faulted response of EHV systems to be simulated for a variety of different single-pole switching schemes. These include conventional single-pole switching, the hybrid method of autoreclosure, the neutral switched ...

1986-01-01

164

Evaluation of Aution Max AX-4030 and 9UB Uriflet, 10PA Aution Sticks urine dipsticks in the automated urine test strip analysis.  

Science.gov (United States)

Abstract Background: Aution Max AX-4030, a test strip analyzer recently introduced to the market, represents an upgrade of the Aution Max AX-4280 widely employed for urinalysis. This new instrument model can allocate two different test strips at the same time. In the present study the two instruments have been compared together with the usage of Uriflet 9UB and the recently produced Aution Sticks 10PA urine strips, the latter presenting an additional test area for the measurement of urinary creatinine. Methods: Imprecision and correlation between instruments and strips have been evaluated for chemical-physical parameters. Accuracy was evaluated for protein, glucose and creatinine by comparing the semi-quantitative results to those obtained by quantitative methods. The well-known interference effect of high ascorbic acid levels on urine glucose test strip determination was evaluated, ascorbic acid influence was also evaluated on protein and ...

2011-09-26

165

Undergraduate Instruction in Empirical Research Methods in Communication: Assessment and Recommendations  

British Library Electronic Table of Contents (United Kingdom)

This study assesses the current state of undergraduate instruction in empirical research methods in communication and offers recommendations for enhancing such instruction. Responses to an online questionnaire were received from 149 communication-related programs at four-year colleges and universities. Just over 85% of responding programs offered an empirical methods course. Although the course often covered both qualitative and quantitative methods, instruction was heavily slanted toward quantitative methods and topics common to both qualitative and quantitative inquiry. The empirical methods course was usually required for graduation, but it was typically not well integrated with the rest of the curriculum and taken late in students' undergraduate careers. Additional analyses examined st...

2011-01-01

166

Quantitative bone scintigraphy: follow-up of a femoral osteogenic sarcoma in an adolescent girl treated by chemotherapy and by massive allograft  

International Nuclear Information System (INIS)

Fifteen quantitative bone scintigraphies were performed in an adolescent girl during the follow-up of a femoral osteogenic sarcoma treated by chemotherapy and massive allograft. Three hours after injection of the radiopharmaceutical (7.4 MBq/kg of 99mTc-MDP) bone activity was measured in the inferior limbs at several regions of interest centered on the hips, femurs (proximal, middle, distal) and proximal tibias. The variations of relative bone activities A/S (ratio of corresponding counting rates between two homologous regions in the affected A and in the healthy S limb) and of absolute bone activities (expressed in counts/pixel-second) are interpreted as a function of times during treatment. The quantitative results are discussed with regard to main phenomena influencing bone activity in this particular clinical case: bone growth, chemotherapy and neo-osteogenesis in allograft.

167

Quantitation of infectious myonecrosis virus in different tissues of naturally infected Pacific white shrimp, Litopenaeus vannamei, using real-time PCR with SYBR Green chemistry  

British Library Electronic Table of Contents (United Kingdom)

The Pacific white shrimp, Litopenaeus vannamei, is the most important shrimp species in volume in world aquaculture. However, in recent decades, outbreaks of diseases, especially viral diseases, have led to significant economic losses, threatening the sustainability of shrimp farming worldwide. In 2004, Brazilian shrimp farming was seriously affected by a new disease caused by the Infectious myonecrosis virus (IMNV). Thus, disease control based on rapid and sensitive pathogen detection methods has become a priority. In this study, a specific quantitation method for IMNV was developed using real-time PCR with SYBR Green chemistry and viral load of the principal target tissues of chronically infected animals was quantified. The quantitative analysis revealed that mean viral load ranged from ...

2011-01-01

168

Nuclear medicine and imaging research: Quantitative studies in radiopharmaceutical science  

Energy Technology Data Exchange (ETDEWEB)

During the past three years the program has undergone a substantial revitalization. There has been no significant change in the scientific direction of this grant, in which emphasis continues to be placed on developing new or improved methods of obtaining quantitative data from radiotracer imaging studies. However, considerable scientific progress has been made in the three areas of interest: Radiochemistry, Quantitative Methodologies, and Experimental Methods and Feasibility Studies, resulting in a sharper focus of perspective and improved integration of the overall scientific effort. Changes in Faculty and staff, including development of new collaborations, have contributed to this, as has acquisition of additional and new equipment and renovations and expansion of the core facilities. 121 refs., 30 figs., 2 tabs.

1991-06-01

169

Groundtruth approach to accurate quantitation of fluorescence microarrays  

Energy Technology Data Exchange (ETDEWEB)

To more accurately measure fluorescent signals from microarrays, we calibrated our acquisition and analysis systems by using groundtruth samples comprised of known quantities of red and green gene-specific DNA probes hybridized to cDNA targets. We imaged the slides with a full-field, white light CCD imager and analyzed them with our custom analysis software. Here we compare, for multiple genes, results obtained with and without preprocessing (alignment, color crosstalk compensation, dark field subtraction, and integration time). We also evaluate the accuracy of various image processing and analysis techniques (background subtraction, segmentation, quantitation and normalization). This methodology calibrates and validates our system for accurate quantitative measurement of microarrays. Specifically, we show that preprocessing the images produces results significantly closer to the known ground-truth for these samples.

2000-12-01

170

Combining adjusted and unadjusted findings in mixed research synthesis  

British Library Electronic Table of Contents (United Kingdom)

Abstract Rationale, aims and objectives- Finding ways to incorporate disparate types of evidence into research syntheses has the potential to build a better evidence base for clinical practice and policy. Yet conducting such mixed research synthesis studies is challenging. Researchers have to determine whether and how to use adjusted and unadjusted quantitative findings in combination with each other and with qualitative findings. Methods- Among quantitative findings, adjustment for confounding, either via study design or statistical analysis, can be a considerable source of heterogeneity. Yet there is no consensus about the best way to synthesize findings resulting from different methods for addressing confounding. When synthesizing qualitative and quantitative findings, additional consid...

2011-01-01

171

Automation in urinalysis: evaluation of three urine test strip analysers.  

Science.gov (United States)

A clinical laboratory evaluation was conducted on the Clinitek Auto 2000, the Super Aution Analyzer and the Urotron RL9 for the determination of glucose, protein, pH, blood, ketone-bodies and bilirubin.Precision of the systems was tested using three commercial control urine materials, and reported as the percentage of times the instrument repeats a certain value. Good repeatability was obtained with all the instruments.Accuracy of the systems was evaluated by comparison with quantitative procedures, and to check agreement between methods yielding semi-quantitative and quantitative results, ranges of acceptability were defined, based on the criteria reported in a previous paper [2]. It was then found that 87.5 to 98.9% of results from the Urotron RL9 and the Clinitek Auto 2000 were acceptable. With the Super Aution Analyzer the level of agreement was apparently lower because of the higher number of concentration steps used ...

1988-01-01

172

High-resolution magnetic resonance imaging: three-dimensional trabecular bone architecture and biomechanical properties.  

Science.gov (United States)

The purpose of this study was to use high-resolution magnetic resonance (MR) imaging combined with image analysis to investigate the three-dimensional (3D) trabecular structure, anisotropy, and connectivity of human vertebral, femoral, and calcaneal specimens. The goal was to determine whether: (a) MR-derived measures depict known skeletal-site-specific differences in architecture and orientation of trabeculae; (b) 3D architectural parameters combined with bone mineral density (BMD) improve the prediction of the elastic modulus using a fabric tensor formulation; (c) MR-derived 3D architectural parameters combined with BMD improve the prediction of strength using a multiple regression model, and whether these results corresponded to the results obtained using higher resolution depictions of trabecular architecture. A total of 94 specimens (12 x 12 x 12 mm cubes) consisting of trabecular bone only were obtained, of which there were 7 from the calcaneus, 15 from distal femur, 47 from the ...

1998-05-01

173

solQTL: a tool for QTL analysis, visualization and linking to genomes at SGN database  

UK PubMed Central (United Kingdom)

BackgroundA common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs requires...Full Text Available

174

Use of DNA ladders for reproducible protein fractionation by SDS-PAGE for quantitative proteomics  

UK PubMed Central (United Kingdom)

In proteomics, one-dimensional (1D) SDS-PAGE is widely used for protein fractionation prior to mass spectrometric analysis to enhance dynamic range of analysis and to improve identification...Full Text Available

2008-02-01

175

Tissue distribution of brain-thymus shared antigens recognized by anti-brain xenosera in the rat, dog and man.  

UK PubMed Central (United Kingdom)

A comparative and quantitative study of the tissue distribution of brain-thymus shared antigens was carried out using rabbit antisera to rat, dog and human brain homogenates, assayed on rat, dog and...Full Text Available

1979-03-01

176

The inhibition of tumor cell intravasation and subsequent metastasis through the regulation of in vivo tumor cell motility by the tetraspanin CD151  

UK PubMed Central (United Kingdom)

SummaryIn vivo tumor cell migration through integrin-dependent pathways is key to the metastatic behavior of malignant cells. Using quantitative in vivo...Full Text Available

2008-03-01

177

Subventricular Zone Cell Migration: Lessons from Quantitative Two-Photon Microscopy  

UK PubMed Central (United Kingdom)

Neuroblasts born in the adult subventricular zone (SVZ) migrate long distances in the rostral migratory stream (RMS) to the olfactory bulbs where they integrate into circuitry as functional interneurons....Full Text Available

178

Study on the transient piping vibration of power plant. Secondary piping system of Wolsung 1 unit.  

Science.gov (United States)

In order to maintain a safe operation and availability of generating facilities, qualitative and quantitative assessment of piping vibration was performed vibration sources and damages of piping support was identified on the second piping system of Wolsun...

1996-01-01

179

Study of building materials impregnation processes by quasi-real-time neutron radiography  

International Nuclear Information System (INIS)

Neutron radiography (NR) is a useful non-destructive method for determination of hydrogen content in various building and technical materials. Monitoring of transport processes of moisture and hydrogenous liquids in porous building materials is enabled by fast, quasi-real-time NR methods based on novel imaging plate neutron detectors (IP-NDs). Hydrogen content in the samples is determined by quantitative analysis of measured profiles of neutron attenuation in the samples. Detailed description of quantitative NR method is presented by the authors in another accompanying contribution at this conference. Deterioration of building materials is originated by different processes that all require presence of water therefore it is essential to limit or prevent the transport of water through the porous material. In this presentation, results of a study of clay brick impregnation by silicone based hydrophobic agents will be presented. ...

1999-11-03

180

Structure of lipid bilayers  

UK PubMed Central (United Kingdom)

The quantitative experimental uncertainty in the structure of fully hydrated, biologically relevant, fluid (Lα) phase lipid bilayers has been too large to...Full Text Available

2000-11-10

181

Solid-Phase Radioimmunoassay of Total and Influenza-Specific Immunoglobulin G  

UK PubMed Central (United Kingdom)

An antigen-antibody system of polystyrene tubes coated with immunoglobulin antibody was used for quantitating immunoglobulins. A similar radioimmunoassay method was adapted for a viral antigen-antibody...Full Text Available

1972-02-01

182

Quantitative bone scintigraphy in children and adolescents. Age dependence of skeleton uptake  

International Nuclear Information System (INIS)

French ... Orig. Title Scintigraphie osseuse quantifiee chez l'enfant et l'adolescent - repartition selon l'age des taux de fixation de diverses pieces osseuses normales.

183

Quantitative bone scintigraphy and 24-hour whole-body counting of [sup 99m]Tc-methylene diphosphonate in patients with prostatic carcinoma  

Energy Technology Data Exchange (ETDEWEB)

Thirty-four patients with prostatic carcinoma were studied with quantitative bone scintigraphy and whole-body counting (WBC) 1 and 24 h after injection of [sup 99m]Tc-MDP before as well as two weeks and two months after orchiectomy. Thirteen of the patients had normal bone scintigrams and WBR at the three different investigations; 21 had skeletal metastases. The latter showed throughout the study higher local gamma camera count rates as well as WBR values than the patiens with normal scintigrams. In these patients a ''flare phenomenon'', with an increase in count rate two weeks after orchiectomy followed by a decrease two months post-operatively, was seen with quantitative bone scintigraphy but not with WBC. However, WBC may be a valuable method indicating the total extent of skeletal metastases in the body, while quantitative bone scintigraphy is more accurate in the interpretation of ...

1992-10-01

184

Quantitative bone scintigraphy and 24-hour whole-body counting of "9"9"mTc-methylene diphosphonate in patients with prostatic carcinoma  

International Nuclear Information System (INIS)

Thirty-four patients with prostatic carcinoma were studied with quantitative bone scintigraphy and whole-body counting (WBC) 1 and 24 h after injection of "9"9"mTc-MDP before as well as two weeks and two months after orchiectomy. Thirteen of the patients had normal bone scintigrams and WBR at the three different investigations; 21 had skeletal metastases. The latter showed throughout the study higher local gamma camera count rates as well as WBR values than the patiens with normal scintigrams. In these patients a ''flare phenomenon'', with an increase in count rate two weeks after orchiectomy followed by a decrease two months post-operatively, was seen with quantitative bone scintigraphy but not with WBC. However, WBC may be a valuable method indicating the total extent of skeletal metastases in the body, while quantitative bone scintigraphy is more accurate in the interpretation of individual skeletal metastases. (orig.).

185

Quantitative and Qualitative Usage Data of an Internet-Based Asthma Monitoring Tool  

UK PubMed Central (United Kingdom)

Background In May 2000, AstraZeneca launched a Web service for asthma patients and health-care providers called LinkMedica, which includes an asthma diary for...Full Text Available

186

Quantitative analysis of the disopyramide concentration-effect relationship.  

UK PubMed Central (United Kingdom)

1. A combined pharmacokinetic-pharmacodynamic model has been used to analyse the relationship between QT prolongation and changes in plasma concentration which occurred after disopyramide was given...Full Text Available

1980-01-01

187

Quantitative Skeletal Histology in Untreated End-stage Renal Failure  

UK PubMed Central (United Kingdom)

Forty-six patients with end-stage renal failure were subjected to iliac crest biopsy before the initiation of a dialysis programme and regardless of the presence of skeletal symptoms....Full Text Available

1973-06-30

188

Quantitative PCR Assay for Mycobacterium pseudoshottsii and Mycobacterium shottsii and Application to Environmental Samples and Fishes from the Chesapeake Bay?  

UK PubMed Central (United Kingdom)

Striped bass (Morone saxatilis) in the Chesapeake Bay are currently experiencing a very high prevalence of mycobacteriosis associated with newly described Mycobacterium...Full Text Available

2010-09-01

189

Quantitative Analysis of Endocytosis and Turnover of Epidermal Growth Factor (EGF) and EGF Receptor  

UK PubMed Central (United Kingdom)

Binding of epidermal growth factor (EGF) to the EGF receptor (EGFR) initiates signal transduction, ultimately leading to altered gene expression. Ligand-activated EGFR is also rapidly internalized...Full Text Available

2010-03-01

190

Qualitative and Quantitative Effects of Treatment for Dental Fear and Avoidance  

UK PubMed Central (United Kingdom)

In a Swedish community-based program for the treatment of dental phobic patients, a clinical trial was performed among 99 severely phobic individuals with long-standing avoidance of dental treatment....Full Text Available

1986-01-01

191

QTL detection by multi-parent linkage mapping in oil palm (Elaeis guineensis Jacq.)  

UK PubMed Central (United Kingdom)

A quantitative trait locus (QTL) analysis designed for a multi-parent population was carried out and tested in oil palm (Elaeis guineensis Jacq.), which is a diploid cross-fertilising...Full Text Available

2010-05-01

192

Probing the Mechanisms of an Air Amplifier using a LTQ-FT-ICR-MS and Fluorescence Spectroscopy  

UK PubMed Central (United Kingdom)

We report the first quantitative assessment of electrosprayed droplet/ion focusing enabled by the use of a voltage-assisted air amplifier between an electrospray ionization emitter and a hybrid...Full Text Available

2007-11-01

193

Precise temporal control of the eye regulatory gene Pax6 via enhancer-binding site affinity  

UK PubMed Central (United Kingdom)

How transcription factors interpret the cis-regulatory logic encoded within enhancers to mediate quantitative changes in spatiotemporally restricted expression patterns during animal...Full Text Available

2010-05-15

194

Practical Applications of the Bioinformatics Toolbox for Narrowing Quantitative Trait Loci  

UK PubMed Central (United Kingdom)

Dissecting the genes involved in complex traits can be confounded by multiple factors, including extensive epistatic interactions among genes, the involvement of epigenetic regulators, and the variable...Full Text Available

2008-12-01

195

Pion-induced fission  

Energy Technology Data Exchange (ETDEWEB)

The A(..pi../sup +/,/sup 3/He)B reaction near threshold is studied in a model where the pion is absorbed by an /sup 4/He constituent of the target nucleus. The predictions of this model using harmonic oscillator cluster wave functions agree semi-quantitatively with the experimental data on the inverse reaction.

1982-03-10

196

Physical Morphology and Quantitative Characterization of Chemical Changes of Weathered PVC/Pine Composites.  

Science.gov (United States)

This study investigated weathering effects on polyvinyl chloride (PVC) based wood plastic composites (WPC), with a focus on the color and structure that is attributed to the material composition. It is directed towards quantifying the main chemical modifi...

2009-01-01

197

Pattern formation and traveling waves in myxobacteria: Theory and modeling  

UK PubMed Central (United Kingdom)

Recent experiments have provided new quantitative measurements of the rippling phenomenon in fields of developing myxobacteria cells. These measurements have enabled us to develop a mathematical model...Full Text Available

2001-12-18

198

Palliative Care Physicians' Religious / World View and Attitude Towards Euthanasia: A Quantitative Study Among Flemish Palliative Care Physicians  

UK PubMed Central (United Kingdom)

Aims:To Study the religious and ideological views and practice of Palliative Care physician towards Euthanasia.Materials and Methods:An...Full Text Available

2009-01-01

199

Observations on computerized quantitative bone scintigraphy in renal osteodystrophy  

Energy Technology Data Exchange (ETDEWEB)

Skeletal radiotracer (sup(99m)Tc-HEDP) uptake was quantitated with and without the aid of a computer in 30 chronic dialysis patients with histologic evidence of renal osteodystrophy. Before scintigraphy, elevated soft-tissue activity due to the absence of renal radiotracer excretion was reduced by hemodialysis. The results were compared with those of a normal group and with the results of the biochemical and the bone morphometric studies of these patients. In all patients the radiotracer uptake was elevated, often markedly. In several patients with minimal histologic bone disease, however, soft-tissue activity could not be normalized by hemodialysis although its influence on the quantitative data could be further reduced (but not excluded) by computer evaluation of skeletal radiotracer uptake. Since the latter technique clearly distinguished the majority of the patients from the normals, it appears that computerized ...

1984-09-01

200

Observations on computerized quantitative bone scintigraphy in renal osteodystrophy  

International Nuclear Information System (INIS)

Skeletal radiotracer (sup(99m)Tc-HEDP) uptake was quantitated with and without the aid of a computer in 30 chronic dialysis patients with histologic evidence of renal osteodystrophy. Before scintigraphy, elevated soft-tissue activity due to the absence of renal radiotracer excretion was reduced by hemodialysis. The results were compared with those of a normal group and with the results of the biochemical and the bone morphometric studies of these patients. In all patients the radiotracer uptake was elevated, often markedly. In several patients with minimal histologic bone disease, however, soft-tissue activity could not be normalized by hemodialysis although its influence on the quantitative data could be further reduced (but not excluded) by computer evaluation of skeletal radiotracer uptake. Since the latter technique clearly distinguished the majority of the patients from the normals, it appears that computerized ...

201

Neutron data requirements for calculating transactinide isotope build-up in reactors  

International Nuclear Information System (INIS)

Based on a generalized theory of perturbations and on non-linear programming an approach to the quantitative determination of necessary accuracies for nuclear data is described. It is used to calculate transactinide isotope build-up in reactors.

1979-08-01

202

Mechanistic insights from a quantitative analysis of pollen tube guidance  

UK PubMed Central (United Kingdom)

BackgroundPlant biologists have long speculated about the mechanisms that guide pollen tubes to ovules. Although there is now evidence that ovules emit a diffusible attractant, little...Full Text Available

203

Measuring the efficacy of anti-malarial drugs in vivo: quantitative PCR measurement of parasite clearance  

UK PubMed Central (United Kingdom)

BackgroundArtemisinin-based combination therapy, currently considered the therapy of choice for uncomplicated Plasmodium falciparum malaria in endemic countries,...Full Text Available

204

Localization of gold in synovial membrane of rheumatoid arthritis treated with sodium aurothiomalate. Studies by electron microscope and electron probe x-ray microanalysis.  

UK PubMed Central (United Kingdom)

The localization of gold in the synovial membrane of rheumatoid arthritis patients treated with sodium aurothiomalate was examined and quantitative analysis of epon-embedded sections was carried out...Full Text Available

1977-06-01

205

Immunoradiometric measurement of the factor VIII procoagulant antigen.  

UK PubMed Central (United Kingdom)

A fluid-phase immunoradiometric assay has been developed which identifies an antigen on the Factor VIII (antihemophilic factor) procoagulant protein. This sensitive and quantitative assay is not influenced...Full Text Available

1978-11-01

206

Image-based modeling of tumor shrinkage in head and neck radiation therapy1  

UK PubMed Central (United Kingdom)

Purpose: Understanding the kinetics of tumor growth∕shrinkage represents a critical step in quantitative assessment of therapeutics and realization of adaptive radiation therapy....Full Text Available

2010-05-01

207

High-Throughput Screen for Poly-3-Hydroxybutyrate in Escherichia coli and Synechocystis sp. Strain PCC6803  

UK PubMed Central (United Kingdom)

A novel, quantitative method for detecting poly-3-hydroxybutyrate (PHB) amounts in viable cells was developed to allow for high-throughput screening of mutant libraries. The staining technique was demonstrated...Full Text Available

2006-05-01

208

Gravitropism: Interaction of Sensitivity Modulation and Effector Redistribution 1  

UK PubMed Central (United Kingdom)

Our increasing capabilities for quantitative hormone analysis and automated high resolution growth studies have allowed a reassessment of the classical Cholodny-Went hypothesis of gravitropism. According...Full Text Available

1991-01-01

209

Gene expression patterns in four brain areas associate with quantitative measure of estrous behavior in dairy cows  

UK PubMed Central (United Kingdom)

BackgroundThe decline noticed in several fertility traits of dairy cattle over the past few decades is of major concern. Understanding of the genomic factors underlying fertility,...Full Text Available

210

Functional pools of oxidative and glycolytic fibers in human muscle observed by 31P magnetic resonance spectroscopy during exercise.  

UK PubMed Central (United Kingdom)

Quantitative probing of heterogeneous regions in muscle is feasible with phosphorus-31 magnetic resonance spectroscopy because of the differentiation of metabolic patterns of glycolytic and oxidative...Full Text Available

1987-12-01

211

Free and Conjugated Indole-3-Acetic Acid in Developing Bean Seeds 1  

UK PubMed Central (United Kingdom)

The changes in conjugated indole-3-acetic acid (IAA) levels compared to the levels of free IAA have been analyzed during the development of bean (Phaseolus vulgaris L.) seed using quantitative...Full Text Available

1989-10-01

212

Evolution of Nitrogen Oxide(s) during In Vivo Nitrate Reductase Assay of Soybean Leaves  

UK PubMed Central (United Kingdom)

Studies were conducted to quantitate the evolution of nitrogen oxides (NO(x)) from soybean [Glycine max (L.) Merr.] leaves during in vivo nitrate reductase...Full Text Available

1981-12-01

213

Effect of pH and Temperature on Denitrification Gene Expression and Activity in Pseudomonas mandelii?  

UK PubMed Central (United Kingdom)

Pseudomonas mandelii liquid cultures were studied to determine the effect of pH and temperature on denitrification gene expression, which was quantified by quantitative reverse transcription-PCR....Full Text Available

2009-06-01

214

Determination of Salirasib (S-trans, trans-farnesylthiosalicylic acid) in human plasma using liquid chromatography-tandem mass spectrometry  

UK PubMed Central (United Kingdom)

A liquid chromatography/tandem mass spectrometric (LC/MS/MS) assay was developed for the quantitative determination of salirasib (S-trans, trans-farnesylthiosalicylic acid,...Full Text Available

2008-06-15

215

Delineation of the Middle Longitudinal Fascicle in Humans: A Quantitative, In Vivo, DT-MRI Study  

UK PubMed Central (United Kingdom)

Experimental and imaging studies in monkeys have outlined various long association fiber bundles within the temporoparietal region. In the present study the trajectory of the middle longitudinal fascicle...Full Text Available

2009-04-01

216

Cytoplasmic pH Regulation in Acer pseudoplatanus Cells  

UK PubMed Central (United Kingdom)

Qualitative and quantitative aspects of the mechanisms involved in the regulation of cytoplasmic pH during an acid-load have been studied in Acer pseudoplatanus cells. Two main processes,...Full Text Available

1986-11-01

217

Ct3d: tracking microglia motility in 3D using a novel cosegmentation approach  

UK PubMed Central (United Kingdom)

Motivation: Cell tracking is an important method to quantitatively analyze time-lapse microscopy data. While numerous methods and tools exist for tracking cells in 2D time-lapse images,...Full Text Available

2011-02-15

218

Comparison of Optical and SEM BSE Imaging Techniques for Quantifying Alpha-Beta Titanium Alloy Microstructures (Preprint).  

Science.gov (United States)

Quantitative metallography is often used to confirm the proper processing of aerospace metallic materials. A microstructural feature of great importance for titanium alloys processed in the alpha-beta phase field is the volume fraction of primary alpha. S...

2006-01-01

219

Bimodal MR-PET agent for quantitative pH imaging  

UK PubMed Central (United Kingdom)

Activatable or “smart” magnetic resonance contrast agents have relaxivities that depend on environmental factors such as pH or enzymatic activity, but the MR signal depends on...Full Text Available

2010-03-22

220

Bedload measurements, East Fork River, Wyoming  

UK PubMed Central (United Kingdom)

A bedload trap in the riverbed provided direct quantitative measurement of debris-transport rate in the East Fork River, Wyoming, a basin of 466 km2 drainage area. Traction load moves only...Full Text Available

1976-04-01

221

Bacterial Oxidation of Sulfide Minerals in Column Leaching Experiments at Suboptimal Temperatures  

UK PubMed Central (United Kingdom)

The purpose of the work was to quantitatively characterize temperature effects on the bacterial leaching of sulfide ore material containing several sulfide minerals. The leaching was tested at eight...Full Text Available

1992-02-01

222

Augmenting Clinical Evaluation of Hemiparetic Arm Movement With a Laboratory-Based Quantitative Measurement of Kinematics as a Function of Limb Loading  

UK PubMed Central (United Kingdom)

BackgroundKinematic and kinetic measurements used in laboratory settings can quantify upper extremity movement impairment following stroke, but their relationship...Full Text Available

2008-01-01

223

Arabidopsis thaliana auxotrophs reveal a tryptophan-independent biosynthetic pathway for indole-3-acetic acid.  

UK PubMed Central (United Kingdom)

We used tryptophan auxotrophs of the dicot Arabidopsis thaliana (wall cress) to determine whether tryptophan has the capacity to serve as a precursor to the auxin, indole-3-acetic acid (IAA). Quantitative...Full Text Available

1993-11-01

224

Application of alpha and gamma spectroscopy to the quantitative analysis of transuranium nuclides in nuclear fuel  

Energy Technology Data Exchange (ETDEWEB)

In nuclear fuel with a burn-up of 33 kg/t U and 52 kg/t U 15 transuranium nuclides /sup 237/Np to /sup 246/Cm have been determined by alpha and gamma spectroscopy after radiochemical separation.

1984-11-01

225

Analysis of trigeminal nerve disorders after oral and maxillofacial intervention  

UK PubMed Central (United Kingdom)

BackgroundQuantitative sensory testing (QST) is applied to evaluate somatosensory nerve fiber function in the spinal system. This study uses QST in patients with sensory dysfunctions...Full Text Available

226

Analysis of Quantitative Interactions between Two Species of Arbuscular Mycorrhizal Fungi, Glomus mosseae and G. intraradices, by Real-Time PCR  

UK PubMed Central (United Kingdom)

Arbuscular mycorrhizal fungi (AMF) are obligate biotrophs, known to play an important role in ecological processes. Conventional light microscopy is the most common method used to detect their presence...Full Text Available

2006-06-01

227

An ounce of prevention or a pound of cure: bioeconomic risk analysis of invasive species.  

UK PubMed Central (United Kingdom)

Numbers of non-indigenous species--species introduced from elsewhere - are increasing rapidly worldwide, causing both environmental and economic damage. Rigorous quantitative risk-analysis frameworks,...Full Text Available

2002-12-07

228

Advances in metallography. Fortschritte in der Metallographie  

Energy Technology Data Exchange (ETDEWEB)

The 52 papers discuss the following subjects: 1. Preparation and structural development; 2. Structural constitution; 3. Structural formation and phase transition; 4. Structure and mechanical properties; 5. Structural formation of metallic and nonmetallic materials; 6. Quantitative metallography, and 7. Quality assurance.

1983-01-01

229

A double antibody solid phase assay for DNA autoantibodies for clinical use.  

UK PubMed Central (United Kingdom)

DNA antoantibodies in serum will bind to antigen-coated polystyrene tubes and can be detected by radiolabelled anti-immunoglobulin. The method is quantitative, gives information on the antibody class...Full Text Available

1976-08-01

230

A Rapid Murine Coma and Behavior Scale for Quantitative Assessment of Murine Cerebral Malaria  

UK PubMed Central (United Kingdom)

BackgroundCerebral malaria (CM) is a neurological syndrome that includes coma and seizures following malaria parasite infection. The pathophysiology is not fully understood and cannot...Full Text Available

231

Theoretical approach on microscopic bases of stochastic functional self-organization: quantitative measures of the organizational degree of the environment  

International Nuclear Information System (INIS)

There has been increased theoretical and experimental research interest in autonomous mobile robots exhibiting cooperative behaviour. This paper provides consistent quantitative measures of organizational degree of a two-dimensional environment. We proved, by the way of numerical simulations, that the theoretically derived values of the feature are reliable measures of aggregation degree. The slope of the feature's dependence on memory radius leads to an optimization criterion for stochastic functional self-organization. We also described the intellectual heritages that have guided our research, as well as possible future developments. (author)

2001-11-30

232

Quantitative density measurements from a real-time neutron radiography system  

Energy Technology Data Exchange (ETDEWEB)

An advanced video system has been assembled from commercially available equipment to support the real-time neutron radiography facility established jointly by the University of Virginia Department of Nuclear Engineering and Engineering Physics, and the Philip Morris Research Center. A schematic diagram of the equipment used for real-time neutron radiography is presented. To obtain quantitative density measurements with this system, several modifications of both hardware and image processing software were required. After implementation of these changes, the system was capable of determining material densities by measuring the degree of neutron attenuation.

1986-01-01

233

Quantitative density measurements from a real-time neutron radiography system  

International Nuclear Information System (INIS)

An advanced video system has been assembled from commercially available equipment to support the real-time neutron radiography facility established jointly by the University of Virginia Department of Nuclear Engineering and Engineering Physics, and the Philip Morris Research Center. A schematic diagram of the equipment used for real-time neutron radiography is presented. To obtain quantitative density measurements with this system, several modifications of both hardware and image processing software were required. After implementation of these changes, the system was capable of determining material densities by measuring the degree of neutron attenuation.

1986-11-16

234

Quantitative bone scintigraphy in the evaluation of angular deformity of the lower extremity  

International Nuclear Information System (INIS)

A technique for quantitative analysis of growth plates in varus or valgus deformity about the knee has been developed. Computer-generated regions of interest are placed on magnification scintigraphs to divide distal femoral and proximal tibial physes into four equal segments. The ratio of counts in the medial half to counts in the lateral half was studied in 31 children (22 normal, 9 with angular deformity). Normal ratios were 0.74 to 0.98 for femora and 0.98 to 1.20 for tibias. In eight of nine patients with deformity, the ratio was abnormal; in two patients the ratio returned to normal when the deformity ceased to progress.

235

Quantitative analysis of iodine in thyroidin. II. Method of combustion in flask with oxygen  

Energy Technology Data Exchange (ETDEWEB)

The authors experimentally study the separate stages of the determination of iodine in thyroidin by the combustion method in a flask with oxygen. The monotypic, conventional procedures and the procedure of Kolii and Pakhomov were studied. With addition of potassium iodide, a sixfold amount (compared with the initial) of iodine is liberated. Further, the liberated iodine is titrated by sodium thiosulfate. The authors find the degree of influence of a high nitrogen content on the determination of iodine in organic compounds. The procedure developed for the quantitative determination of the iodine in thyroidin by the combustion method is simple, fairly rapid, and can be used for the reliable control of the quality of thyroidin preparations and its starting raw material.

1986-11-01

236

Mass fragmentographic determination of polymethylnaphthalene and polymethylphenanthrene in a crude oil and in marine organisms  

Energy Technology Data Exchange (ETDEWEB)

The investigation of the petroleum contamination in marine organisms requires the trace level quantitative determination of indicative substances to be identified by a fingerprint of petroleum. Polymethylnaphthalene (PMN) and polymethylphenanthrene (PMP) were chosen because of their simple separation from a crude oil by means of an activated charcoal chromatography, their relatively high existence in aromatic compounds, and their persistence relative to other petroleum components in the tissue of oil contaminated marine organisms. The purpose of this paper is to present an activated charcoal chromatographic separation procedure of PMN and PMP in a crude oil and a trace level quantitative analytical method of them in marine organisms by mass fragmentography (MF).

1980-09-01

237

Fuzzy performance measurement of a supply chain in manufacturing companies  

British Library Electronic Table of Contents (United Kingdom)

This paper is aimed to present a fuzzy decision making approach to deal with the performance measurement in supply chain systems. In the manufacturing environment, performance measurement is based on different quantitative and qualitative factors. Some of these factors may have a larger effect on the performance measure than others. Units of measure of the quantitative factors are different such as time, money, percentage, ratio, and counts. Thus, this paper presents a performance measurement approach based on fuzzy set theory and the pair-wise comparison of Analytical Hierarchy Process (AHP), which ensures the consistency of the designer's assignments of importance of one factor over another to find the weight of each of the manufacturing activity in the departmental organization. In the ...

2011-01-01

238

Effects of carbocalcitonin treatment on PAGET's disease assessed by quantitative bone scintigraphy  

International Nuclear Information System (INIS)

Sixteen patients with PAGET's disease of bone underwent quantitative bone scintigraphy with "9"9"mTc-MDP before and after a long-term treatment with carbocalcitonin, a synthetic analogue of eel calcitonin. The radionuclide study consisted in the blood pool and bone uptake measurement and in the bone avidity calculation (bone uptake - blood pool ratio). In our patients, a significant decrease in bone uptake and bone avidity was found, whereas the blood pool remained statistically unchanged. This behaviour could be accounted for the shift of the compact bone to a lamellar pattern. (orig.).

239

Effects of carbocalcitonin treatment on PAGET's disease assessed by quantitative bone scintigraphy  

Energy Technology Data Exchange (ETDEWEB)

Sixteen patients with PAGET's disease of bone underwent quantitative bone scintigraphy with /sup 99m/Tc-MDP before and after a long-term treatment with carbocalcitonin, a synthetic analogue of eel calcitonin. The radionuclide study consisted in the blood pool and bone uptake measurement and in the bone avidity calculation (bone uptake - blood pool ratio). In our patients, a significant decrease in bone uptake and bone avidity was found, whereas the blood pool remained statistically unchanged. This behaviour could be accounted for the shift of the compact bone to a lamellar pattern.

1988-06-01

240

Development of safety function assessment trees for pressurized heavy water reactor LP/SD operations  

Energy Technology Data Exchange (ETDEWEB)

The objective of Configuration Risk Management Program(CRMP) is to maintain the safety level by assuring the defense-in-depth of nuclear power plant while the configurations are changed during plant operations, especially for the LP/SD. Such a safety purpose can be achieved by establishing the risk monitoring programs with both quantitative and qualitative features. Generally, the quantitative risk evaluation models, i.e., PRA models are used for the risk evaluation during full power operation, and the qualitative risk evaluation models such as safety function assessment trees are used. Through this study, safety function assessment trees were developed.

2003-10-01

241

Growth of ytterbium tartrate trihydrate crystals in silica and agar-agar gels and their characterization  

British Library Electronic Table of Contents (United Kingdom)

Single crystals of ytterbium tartrate trihydrate have been grown by gel method using silica and agar-agar gels as media of growth. The medium of growth influences the morphology of grown crystals, silica gel yielding single and polycrystalline in the form of spherulites whereas agar-agar gel leading to growth of single and twinned crystals. Materials grown as single crystals have been characterized by using optical and scanning electron microscopy (SEM), EDAX, XRD, FT-IR, CHN and thermogravimetric techniques. The stoichiometry of the grown single crystals is suggested to be Yb(C4H4O6) (C4H5O6).3H2O. The FT-IR spectrum shows the presence of singly as well as doubly ionized tartrate ligands. Results of thermal analysis indicate that the material is thermally stable up to a temperature of 200...

2006-01-01

242

Understanding Enzyme Activity Using Single Molecule Tracking (Poster)  

Energy Technology Data Exchange (ETDEWEB)

This poster describes single-molecule tracking and total internal reflection fluorescence microscopy. It discusses whether the carbohydrate-binding module (CBM) moves on cellulose, how the CBM binds to cellulose, and the mechanism of cellulosome assembly.

2009-06-01

243

Triggered single-photon emission from electrically driven InP/(Al,Ga)InP quantum dots  

International Nuclear Information System (INIS)

Semiconductor quantum dots (QDs) are a promising approach to realize a single-photon source. To avoid bulky and expensive laser systems for future applications, electrical excitation is desirable. InP QDs are especially suited, as they emit in the red spectral range and therefore in the optimal range of commercial detectors. Additionally, they have been shown to be capable of emitting single photons up to 80 K. Thus, we embedded InP QDs in the intrinsic region of a p-i-n diode. To form single devices, 100 #mu#m mesas were etched and supplied with electrical contacts. We investigated the electroluminescence from single QDs and performed second-order auto correlation measurements to verify single-photon emission. To prevent expensive helium cooling and reach operation above 80 K, we investigated the influence of elevated temperature on the performance of our device. Since triggered ...

2010-03-21

244

Single-dose pharmacokinetics of ceftriaxone in healthy Chinese adults.  

UK PubMed Central (United Kingdom)

The pharmacokinetics of ceftriaxone were investigated in six healthy mainland Chinese adults (four males and two females). A single 1.0-g dose was administered intravenously or intramuscularly in a...Full Text Available

1985-02-01

245

Single-Hair Follicular Unit Transplant for Stable Vitiligo  

UK PubMed Central (United Kingdom)

Follicular unit transplant (FUT) is one of the surgical procedures which has been recently used to repigment a stable vitiligo patch. Single-hair FUT was done for a 30-year-old male with stable vitiligo...Full Text Available

2011-01-01

246

Single dilepton production at [ital e][sup +][ital e][sup [minus  

Energy Technology Data Exchange (ETDEWEB)

We calculate the cross sections for the single production of doubly charged dileptons, both scalar and vector, at [ital e][sup +][ital e][sup [minus

1994-08-01

247

Results of single and repeat dose studies of the oral matrix metalloproteinase inhibitor marimastat in healthy male volunteers  

UK PubMed Central (United Kingdom)

AimsTo assess the tolerability and pharmacokinetic profile of single and repeat doses of the oral matrix metalloproteinase inhibitor marimastat in healthy male volunteers.Full Text Available

1998-01-01

248

Properties of single nerve fibres that evoke blood flow changes in cat dental pulp  

UK PubMed Central (United Kingdom)

Single nerve fibres innervating tooth pulp were isolated from filaments dissected from the inferior alveolar nerve in 17 anaesthetized cats. The fibres were studied to determine whether electrical stimulation...Full Text Available

2002-08-01

249

Myelomatous Pleural Effusion: A Case Series in a Single Institution and Literature Review  

UK PubMed Central (United Kingdom)

BackgroundMyelomatous pleural effusion (MPE) is rare in myeloma patients. We present a consecutive series of patients with MPE in a single institution.MethodsWe...Full Text Available

2011-10-01

250

Multiple-Bond Kinetics from Single-Molecule Pulling Experiments: Evidence for Multiple NCAM Bonds  

UK PubMed Central (United Kingdom)

The kinetic parameters of single bonds between neural cell adhesion molecules were determined from atomic force microscope measurements of the forced dissociation of the homophilic protein-protein bonds....Full Text Available

2005-11-01

251

Modified Therapeutic Community for Co-Occurring Disorders: Single Investigator Meta Analysis  

UK PubMed Central (United Kingdom)

This paper presents the results of a meta-analysis for a single investigator examining the effectiveness of the modified therapeutic community (MTC) for clients with co-occurring substance use...Full Text Available

2010-07-01

252

Mapping neuropeptide expression by mass spectrometry in single dissected identified neurons from the dorsal ganglion of the nematode Ascaris suum  

UK PubMed Central (United Kingdom)

We have developed a method for dissecting single neurons from the nematode Ascaris suum, in order to determine their peptide content by mass spectrometry (MS). In this paper,...Full Text Available

2010-07-21

253

Life Stress, Maternal Optimism, and Adolescent Competence in Single Mother, African American Families  

UK PubMed Central (United Kingdom)

Although research demonstrates many negative family outcomes associated with single-parent households, little is known about processes that lead to positive outcomes for these families. Using...Full Text Available

2010-08-01

254

Large plasmids of fast-growing rhizobia: homology studies and location of structural nitrogen fixation (nif) genes.  

UK PubMed Central (United Kingdom)

A single large plasmid was isolated from multiplasmid-harboring strains Rhizobium leguminosarum 1001 and R. trifolii 5. These single plasmids, as well as the largest plasmid detectable in R. phaseoli...Full Text Available

1981-03-01

255

Force-dependent chemical kinetics of disulfide bond reduction observed with single-molecule techniques  

UK PubMed Central (United Kingdom)

The mechanism by which mechanical force regulates the kinetics of a chemical reaction is unknown. Here, we use single-molecule force–clamp spectroscopy and protein engineering to study the effect...Full Text Available

2006-05-09

256

Efficient preparation of internally modified single-molecule constructs using nicking enzymes  

UK PubMed Central (United Kingdom)

Investigations of enzymes involved in DNA metabolism have strongly benefited from the establishment of single molecule techniques. These experiments frequently require elaborate DNA substrates, which...Full Text Available

2011-02-01

257

Comparing Radiation Treatments Using Intensity-Modulated Beams, Multiple Arcs and Single Arc  

UK PubMed Central (United Kingdom)

PurposeA dosimetric comparison between multiple static-field intensity-modulated radiation therapy (IMRT), multi-arc intensity-modulated arc therapy (IMAT) and single-arc...Full Text Available

2010-04-01

258

Anchoring of a Single Molecular Rotor and Its Array on Metal Surfaces using Molecular Design and Self-Assembly  

UK PubMed Central (United Kingdom)

Functionalizing of single molecules on surfaces has manifested great potential for bottom-up construction of complex devices on a molecular scale. We discuss the growth mechanism for the initial layers...Full Text Available

259

An investigation of the distribution of resistivity in single crystal germanium ribbon by the single probe method  

CERN Document Server

Experimental data are reported on the micro-irregularities of resistivity in longitudinal and transverse specimens of germanium 0.5 to 0.8 mm in thickness and 25 to 40 mm in width. These data are correlated with the conditions of growth of the crystals. (16 refs).

1972-01-01

260

Acetylcholine receptor kinetics. A description from single-channel currents at snake neuromuscular junctions.  

UK PubMed Central (United Kingdom)

Single-channel currents from acetylcholine receptor channels of garter snake neuromuscular junctions were recorded using the patch-clamp technique. Low concentrations of acetylcholine or carbamylcholine...Full Text Available

1982-09-01

261

A model for the single stranded random coil form of polydeoxyadenylic acid from minimum energy conformations of the dimeric subunit.  

UK PubMed Central (United Kingdom)

The minimum energy conformations of dApdA have been examined for their suitability as buildings blocks of the single stranded coil form of polynucleotides. Calculations of the characteristic ratio C...Full Text Available

1978-09-01

263

Technology Transfer. Volume 2  

Science.gov (United States)

... table (ASCAMP) system and the Military Strategic and Tactical Relay (Milstar) program. 10 ... Single Channel Antijam Milstar Portable Terminal ...

1992-04-01

264

System protection considerations related to single pole tripping of high-voltage transmission lines  

Science.gov (United States)

Single and selective pole tripping schemes may be used to maintain a desired level of system integrity while minimizing transmission line expenditures. In general, these schemes will be most effective on those portions of the system where relatively few interconnections exist. While selective pole tripping may superficially appear to provide more margin than single pole schemes in the preservation of system stability, it seems unlikely that in those actual applications where single pole tripping is warranted that selective pole tripping will provide any significant advantages.

1975-01-01

265

Sub-wavelength localization of near-fields in coupled metallic spheres for single emitter polarization analysis  

CERN Document Server

We numerically demonstrate selective near-field localization determined by the polarization state of a single emitter coupled to plasmonic nano-cluster. Seven gold nanospheres are carefully arranged such that up to ten polarization states of the single emitter, including linear, circular, and elliptical polarizations, can be distinguished via the distinct field localization in four gaps. The ability to transform polarization state into field spatial localization may find application for single emitter polarization analysis.

2011-01-01

266

Single-Walled Carbon Nanotubes Targeted to the Tumor ...  

Science.gov (United States)

... 1981. Retention of diphenyls, terphenyls, phenylalkanes and fluorene on graphitized thermal carbon black. Chromatographia 14:510-514. ...

2009-09-01

267

Operating Manual for Single-Shot Autocorrelator  

Science.gov (United States)

... pulses by a 50/50 beamsplitter and recombined in space and in time inside a wafer of KDP crystal which generates a second harmonic of the ...

1993-01-01

268

Multidisciplinary management of Ewing's sarcoma : a pragmatic approach  

International Nuclear Information System (INIS)

Treatment of Ewing's sarcoma by radiotherapy, chemotherapy and surgery singly and in combination is reviewed.(M.G.B.).

269

Multicast Queueing Delay: Performance Limits and Order ...  

Science.gov (United States)

... the bound (5). For a network composed of a single source-terminal pair and ... Suboptimality bounds in stochastic control: A queueing example ...

2010-12-10

270

Magnetic properties of single crystalline RE_2PdSi_3 intermetallic compounds  

International Nuclear Information System (INIS)

... susceptibility magnetization magnetoresistance monocrystals order-disorder

273

Advanced Gas Cooling Study for the Hospital at Davis ...  

Science.gov (United States)

... The performance at reduced condenser water temper- atures was assumed to be the same as that of the single-effect unit. ...

1999-01-01

274

Void growth and softening of a single crystal with strain gradient effects  

Energy Technology Data Exchange (ETDEWEB)

The strain gradient crystal plasticity theory is applied to study the deformation of planar single crystal with a void under a nominally uniaxial tension. The crystal theory assumes elevated strain hardening due to slip gradients and has a constitutive length scale. The effects of the void size with respect to the constitutive length scale on the single crystal deformation are investigated.

1997-02-06

275

Single Atom Detection With Optical Cavities  

CERN Document Server

We present a thorough analysis of single atom detection using optical cavities. The large set of parameters that influence the signal-to-noise ratio for cavity detection is considered, with an emphasis on detunings, probe power, cavity finesse and photon detection schemes. Real device operating restrictions for single photon counting modules and standard photodiodes are included in our discussion, with heterodyne detection emerging as the clearly favourable technique, particularly for detuned detection at high power.

2008-01-01

276

Heat transfer augmentation in rod bundles near grid spacers  

International Nuclear Information System (INIS)

Heat transfer augmentation by straight grid spacers in rod bundles is studied for single phase flow and for post critical heat flux dispersed flow. The heat transfer effect of swirling grid spacers in single phase flow is also examined. Governing heat transfer mechanisms are analyzed, and predictive formulations are established. For single phase flow, the local heat transfer at a straight spacer and at its upstream or downstream locations are treated separately. 18 refs.

1980-01-01

277

A single early life seizure impairs short-term memory but does not alter spatial learning, recognition memory, or anxiety  

UK PubMed Central (United Kingdom)

The impact of a single seizure on cognition remains controversial. We hypothesized that a single early life seizure (sELS) on rat post-natal day (P) 7 would alter only hippocampal-dependent...Full Text Available

2008-11-01

278

Transient suppression of MLH1 allows effective single-nucleotide substitution by single-stranded DNA oligonucleotides  

British Library Electronic Table of Contents (United Kingdom)

Short synthetic single-stranded oligodeoxyribonucleotides (ssODNs) can be used to introduce subtle modifications into the genome of mouse embryonic stem cells (ESCs). We have previously shown that effective application of ssODN-mediated gene targeting in ESC requires (transient) suppression of DNA mismatch repair (MMR). However, whereas transient down-regulation of the mismatch recognition protein MSH2 allowed substitution of 3 or 4 nucleotides, 1 or 2 nucleotide substitutions were still suppressed. We now demonstrate that single- or dinucleotide substitution can effectively be achieved by transient down-regulation of the downstream MMR protein MLH1. By exploiting highly specific real-time PCR, we demonstrate the feasibility of substituting a single basepair in a non-selectable gene. Howev...

2011-01-01

279

Single-Access Retroperitoneoscopic Adrenalectomy (SARA) Versus Conventional Retroperitoneoscopic Adrenalectomy (CORA): A Case?Control Study  

British Library Electronic Table of Contents (United Kingdom)

Background Stimulated by the concept of Natural Orifice Transluminal Endoscopic Surgery (NOTES), minimizing the access even further has become a new trend in minimally invasive surgery. We compare our recently described new method of endoscopic single-access adrenalectomy with the conventional retroperitoneoscopic approach in a matched-pairs study. Methods Fifty single-access retroperitoneoscopic adrenalectomies (SARA) were performed in 47 selected patients suffering from Conn?s adenomas (n?=?20), pheochromocytomas (n?=?15), Cushing?s adenomas (n?=?6), and other diseases (n?=?6). For SARA, a single 2-cm skin incision beneath the 12th rib was used. Following creation of the retroperitoneal space with the rigid endoscope, dissection was carried out single-handed. Another 47 patients served a...

2010-01-01

280

NAME=\\  

Wastenet

...Synthesis of low-temperature, fast, single-firing body for porcelain stoneware tiles with coal gangue Synthesis of low-temperature, fast, single-firing body for porcelain stoneware ... tiles with coal gangue Synthesis of low-temperature, fast, single-firing body for porcelain stoneware tiles with coal gangue Wei et al.,... Article Synthesis of low-temperature, fast, single-firing body for porcelain stoneware tiles with coal gangue Qiangwei Wei1, Wenyuan Gao1*, and Xinguo ...According to phase diagram theory, a low-temperature, fast, single-firing body mix for porcelain stoneware tiles was designed in the quaternary system CaO-MgO-Al2O3-SiO2, using ...

281

Equilibrium and thermodynamic parameters of single and binary mixture biosorption of lead (II) and copper (II) ions onto Pseudomonas putida: Effect of temperature  

Energy Technology Data Exchange (ETDEWEB)

The biosorption of lead (II) and copper (II) ions, single component and binary systems, by dried P. putida was investigated in a batch system. The effects of initial pH, temperature, initial single and binary mixture concentrations on the biosorption kinetics and equilibrium uptake of each component, both single and binary mixtures were investigated. The bacterial biomass exhibited the highest single and binary lead (II) and copper (II) ions uptake capacity at 25 and 30 deg. C, respectively, the initial pH value of 5.5 and at the initial metal ions concentration of 100 mg dm{sup -3}. The Freundlich and Langmuir adsorption models were used for the mathematical description of the biosorption equilibrium and isotherm constants were evaluated at different temperatures. Adsorption data were well described by the Langmuir model, although they could be modeled by the Freundlich equation. The thermodynamics ...

2006-07-31

282

The design of hazard risk assessment matrices for ranking occupational health risks and their application in mining and minerals processing.  

Science.gov (United States)

Two hazard risk assessment matrices for the ranking of occupational health risks are described. The qualitative matrix uses qualitative measures of probability and consequence to determine risk assessment codes for hazard-disease combinations. A walk-through survey of an underground metalliferous mine and concentrator is used to demonstrate how the qualitative matrix can be applied to determine priorities for the control of occupational health hazards. The semi-quantitative matrix uses attributable risk as a quantitative measure of probability and uses qualitative measures of consequence. A practical application of this matrix is the determination of occupational health priorities using existing epidemiological studies. Calculated attributable risks from epidemiological studies of hazard-disease combinations in mining and minerals processing are used as examples. These historic response data do not reflect the risks associated with current ...

2001-03-01

283

Quantitative bone scintigraphy in patients with osteoporosis  

International Nuclear Information System (INIS)

Quantitative bone scans were evaluated in 16 patients with osteoporosis and in a control group of 7 healthy subjects. Along with a detailed biochemical analysis of calcium-phosphorus metabolism and standartized reongenographs, a quantitative dynamic bone scintigraphy was performed according to the method proposed by the authors. The bone-accumulating factor K_b was determined on the base of mathematical analysis of the graph reflecting activity changes in bone tissue unit during the investigation, the blood-elimination factor K_h and kidney-elimination factor K_k. In addition the accumulation index AI (in %) was calculated as a relation between the activity in bone tissue unit, registered in 20 min interval, and the activity in soft tissues for the same time. Whereas the static gamma camera scintigraphy, made 3-4 hrs after injecting of the osteotrope radiopharmaceuticals, showed no specific changes in the patients examined, the method proposed ...

284

Quantitative bone scintigraphy in evaluating treatment of renal osteodystrophy  

Energy Technology Data Exchange (ETDEWEB)

The effect of various forms of treatment of renal osteodystrophy was evaluated in 25 dialysis patients by quantitative bone scintigraphy, using 99m-Tc-HEDP. The results were compared with those of biochemical and bone morphometric studies. The total skeletal activity (TSA) decreased in 5 patients after transplantation, in 11 after parathyroidectomy and in 6 out of 9 treated conservatively, but did not normalize in any of the patients. Bone morphometric evaluation of treatment, which could be performed in 19 of the 20 patients who did not receive a transplant, demonstrated a reduction in the degree of hyperparathyroidism in 17 patients (89 percent). Osteoid excess was reduced in 13 patients (68 percent) but an evident reduction of osteomalacic osteoid, i.e. improvement of osteomalacia, occurred in only 4 patients (21 percent). Changes in the TSA correlated significantly with the changes in the biochemical and histological parameters of hyperparathyroidism, but not ...

1983-01-01

285

Quantitative bone scintigraphy in evaluating treatment of renal osteodystrophy  

International Nuclear Information System (INIS)

The effect of various forms of treatment of renal osteodystrophy was evaluated in 25 dialysis patients by quantitative bone scintigraphy, using 99m-Tc-HEDP. The results were compared with those of biochemical and bone morphometric studies. The total skeletal activity (TSA) decreased in 5 patients after transplantation, in 11 after parathyroidectomy and in 6 out of 9 treated conservatively, but did not normalize in any of the patients. Bone morphometric evaluation of treatment, which could be performed in 19 of the 20 patients who did not receive a transplant, demonstrated a reduction in the degree of hyperparathyroidism in 17 patients (89 per cent). Osteoid excess was reduced in 13 patients (68 per cent) but an evident reduction of osteomalacic osteoid, i.e. improvement of osteomalacia, occurred in only 4 patients (21 per cent). Changes in the TSA correlated significantly with the changes in the biochemical and histological parameters of hyperparathyroidism, but ...

286

New insight on the interaction and diffusion properties of ion beam injected self-interstitials in crystalline silicon  

Energy Technology Data Exchange (ETDEWEB)

The diffusion of ion beam injected self-interstitials (I) and their interaction with impurities in crystalline Si has been investigated and modeled. In particular, the I-substitutional carbon (C) interactions have been studied, using a molecular-beam-epitaxy grown Si{sub 1-y}C{sub y} layer interposed between the shallow I-source and a deeper B-spike (marker for I-concentration). Substitutional C atoms are shown to trap I's, to be removed from their substitutional sites, and to form stable precipitates into the C-rich region. The I-trapping mechanism was quantitatively studied by a simulation code. The reactions causing trapping and deactivation are described. In addition, the boron markers approach was extended to the two dimensional (2D) diffusion. High resolution scanning capacitance microscopy was used for quantitative measurements of the 2D boron transient enhanced diffusion induced on a boron delta array by the I's ion ...

2003-05-01

287

New insight on the interaction and diffusion properties of ion beam injected self-interstitials in crystalline silicon  

International Nuclear Information System (INIS)

The diffusion of ion beam injected self-interstitials (I) and their interaction with impurities in crystalline Si has been investigated and modeled. In particular, the I-substitutional carbon (C) interactions have been studied, using a molecular-beam-epitaxy grown Si_1_-_yC_y layer interposed between the shallow I-source and a deeper B-spike (marker for I-concentration). Substitutional C atoms are shown to trap I's, to be removed from their substitutional sites, and to form stable precipitates into the C-rich region. The I-trapping mechanism was quantitatively studied by a simulation code. The reactions causing trapping and deactivation are described. In addition, the boron markers approach was extended to the two dimensional (2D) diffusion. High resolution scanning capacitance microscopy was used for quantitative measurements of the 2D boron transient enhanced diffusion induced on a boron delta array by the I's ion beam injected through a ...

2003-05-01

288

New facility design and work method for the quantitative fit testing laboratory. Master's thesis  

Energy Technology Data Exchange (ETDEWEB)

The United States Air Force School of Aerospace Medicine (USAFSAM) tests the quantitative fit of masks which are worn by military personnel during nuclear, biological, and chemical warfare. Subjects are placed in a Dynatech-Frontier Fit Testing Chamber, salt air is fed into the chamber, and samples of air are drawn from the mask and the chamber. The ratio of salt air outside the mask to salt air inside the mask is called the quantitative fit factor. A motion-time study was conducted to evaluate the efficiency of the layout and work method presently used in the laboratory. A link analysis was done to determine equipment priorities, and the link data and design guidelines were used to develop three proposed laboratory designs. The proposals were evaluated by projecting the time and motion efficiency, and the energy expended working in each design. Also evaluated were the lengths of the equipment links for each proposal, and each ...

1989-05-01

289

Diagnostic capabilities of quantitative bone scintigraphy in ankylosing spondylitis: A comparison with radiography  

International Nuclear Information System (INIS)

In 576 patients quantitative scintigraphy of the sacroiliac joints and the spinal cord with "9"9"mTc-pyrophosphate was performed. 328 were patients with proven ankylosing spondylitis according to the New York criteria. 120 were patients with a clinically and roentgenologically suspected ankylosing spondylitis and 128 persons formed a healthy control group. The count rate in small regions of interest (ROI) in the sacroiliac joints, the spinal cord and the os sacrum were compared on the basis of indexes. The scintigraphic data of patients with ankylosing spondylitis were compared with the healthy control group and with the radiographic findings and radiologic staging of the disease. In a longitudinal follow-up study during 1 to 6 years these investigations were continued together with clinical and roentgenological checks. Quantitative bone scintigraphy provides characteristic indexes for ankylosing spondylitis, indicating the increased mineral ...

290

Comparative evaluation of the quantitative bone scintigraphy and the radiography in patients with ankylosing spondylitis  

International Nuclear Information System (INIS)

In 620 patients quantitative bone scintigraphy with "9"9"mTc pyrophosphate of the sacroiliac joints and of the spine was performed: 365 patients with confirmed ankylosing spondylitis, 125 patients with clinical radiological suspicion for ankylosing spondylitis (probable Bechterev) and control group of 130 healthy individuals. By comparison of the activity in zones of interest of the sacroiliac joints, the spine and sacrum, the following indices were determined: sacroiliac (separately for the left and right sacroiliac joints), index D_1_0/sacrum, index L_4/sacrum and index C_7/sacrum. The scintigraphic finding was compared to the X-ray one and to the radiological stage of the disease. A long-term follow-up of the patients was carried out during 1-6 years with scintigraphic, X-ray and clinical investigations. Emphasis was laid upon the posibilities for quantitative scintigraphy for early diagnostics of ankylosing spondylitis. The combination of ...

291

Assessment of liver circulation by quantitative scintiangiography: Evaluation of the relative contribution of the hepatic arterial and portal venous blood flows to liver perfusion  

Energy Technology Data Exchange (ETDEWEB)

Quantitative hepatic scintiangiography was previously used for evaluating the relative contribution of hepatic arterial and portal venous blood flows to the hepatic circulation. The present study compares 3 different procedures (automatic and manual integration, and slope fitting methods) for analyzing the hepatic time activity curves obtained after bolus i.v. injection of 370 MBq /sup 99m/Tc-diethylentriaminopentacetic acid. Twenty five subjects were studied: Five controls, ten cirrhotics, and ten portal hypertensive patients previously submitted to side to side portacaval anastomosis. The correspondence between results given by the different methods was satisfactory only in shunted patients, and the reproducibility of computed parameters was quite poor for all procedures. Accordingly, none of the methods can be considered as supporting reliable quantitative pathophysiological evaluations. However, the hepatic arterial/portal venous flow ratio ...

1989-04-01

292

X-ray Phase Imaging Microscopy using a Fresnel Zone Plate and a Transmission Grating  

International Nuclear Information System (INIS)

We report on a hard X-ray phase imaging microscopy (a phase-difference microscopy) that consists of an objective and a transmission grating. The simple optical system provides a quantitative phase image, and does not need a wave field mostly coherent on the objective. Our method has a spatial resolution almost same as that of the absorption contrast microscope image obtained by removing the grating. We demonstrate how our approach provides a phase image from experimentally obtained images. Our approach is attractive for easily appending a quantitative phase-sensitive mode to normal X-ray microscopes, and has potentially broad applications in biology and material sciences.

2010-06-23

293

Synthesis of novel tellurium containing analogues of choline and acetylcholine and their quantitation by pyrolysis-gas chromatography-mass spectrometry.  

Science.gov (United States)

Methods for the synthesis and quantitation of the novel choline analogues, telluronium choline and acetyltelluronium choline, are described. An assay procedure utilizing pyrolysis-gas chromatography-mass spectrometry (Py-GC-MS) with cold trapping was developed with [2H4]telluronium choline and [2H4]acetyltelluronium choline as internal standards. The telluronium compounds were ion-pair extracted from tissue with dipicrylamine, washed with 2-butanone, and pyrolyzed prior to GC-MS analysis. The compounds were monitored using selected ion monitoring at m/z 232 and m/z 190 for acetyltelluronium and telluronium choline, respectively, and at m/z 236 and m/z 194 for the analogous deuterated internal standards. The assay was linear over a range of 20 pmol-20 nmol of compound taken through the assay. PMID:8130881

1993-12-31

294

Sustainability evaluation of limestone geothermal reservoirs with extended production histories in Beijing and Tianjin, China  

British Library Electronic Table of Contents (United Kingdom)

Sustainable development of geothermal resources is the key to prolong the commercial life of geothermal fields. This paper uses two well-known geothermal fields in China, with long histories of production, to demonstrate how sustainability can be quantitatively evaluated, and to highlight the essential differences between sustainable and non-sustainable development schemes. After examining the complex nature of sustainability evaluation, fuzzy synthetic evaluation is applied as a tool for the quantitative sustainability rating of geothermal reservoirs. The evaluation procedures include systemic criteria selection, weighing, individual criterion evaluation and finally final multi-criterion decision analysis evaluation. The sustainability of a limestone reservoir in the urban sector of Tianj...

2011-01-01

295

Studies on the acidity of mordenite and ZSM-5. 2. Loss of Broensted acidity by dehydroxylation and dealumination  

Science.gov (United States)

Quantitative determination of Broensted acid site concentrations in calcined H-mordenite and H-ZSM-5 by means of conductometric titration and infrared spectroscopy reveals that the concentration of Broensted acid sites present is lower than would be expected on the basis of the aluminum content. This discrepancy is attributed to dealumination and dehydroxylation processes occurring during calcination. A model is proposed according to which the degree of these processes strongly depends on the concentration of vicinal aluminum T sites in the zeolite: Broensted acid sites associated with these T sites are lost, and the remaining Broensted acidity is related to the concentration of the (remaining) isolated aluminum T sites. This model quantitatively correlates the experimentally determined concentration of Broensted acid sites with the concentration of isolated aluminum T sites. 33 refs., 4 figs., 2 tabs.

1993-01-14

296

Structural aging program to assess the adequacy of critical concrete components in nuclear power plants  

International Nuclear Information System (INIS)

The Structural Aging (SAG) Program is carried out by the Oak Ridge National Laboratory (ORNL) under sponsorship of the United States Nuclear Regulatory Commission (USNRC). The Program has evolved from preliminary studies conducted to evaluate the long-term environmental challenges to light-water reactor safety-related concrete civil structures. An important conclusion of these studies was that a damage methodology, which can provide a quantitative measure of a concrete structure's durability with respect to potential future requirements, needs to be developed. Under the SAG Program, this issue is being addressed through: establishment of a structural materials information center, evaluation of structural component assessment and repair technologies, and development of a quantitative methodology for structural aging determinations. Progress to date of each of these activities is presented as well as future plans. 7 refs., 5 figs.

1989-08-14

297

Quantitative non-destructive evaluation of high-temperature superconducting materials  

Energy Technology Data Exchange (ETDEWEB)

Even though the currently intensive research efforts on high- temperature superconducting materials have not yet converged on a well specified practical material, the indications are that such a material may be quite brittle, anisotropic, and may contain many flaws such as microcracks and voids at grain boundaries. Consequently, practical applications of high temperature superconducting materials will require a very careful strength analysis based on fracture mechanics considerations. Because of the high sensitivity of the strength of such materials to the presence of defects, methods of quantitative non-destructive evaluation may be expected to play an important role in strength determinations. This proposal is concerned with the use of ultrasonic methods to detect and characterize isolated cracks, clusters of microcracks and microcracks distributed throughout the material. Particular attention has been, and will continue to be devoted to relating ultrasonic ...

1991-06-14

298

Quantitative bone scintigraphy. A methodological evaluation in prostate cancer  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To evaluate a simple method for quantification of focal activity in bone scintigraphy (BS). Material and methods: The gamma camera was calibrated using a phantom. Quantitative bone scintigraphy (QBS) was performed on 11 men recently diagnosed with prostate cancer (PCa), for whom routine BS showed involvement of the skeleton. Following endocrine therapy for 4 to 8 months, a second QBS was performed. Changes in QBS values were then compared to changes in serum levels of prostate-specific antigen (PSA). Results: PSA response indicating regression of PCa was accompanied by a decrease in the QBS value in 8 of the 11 patients. The overall mean error of the QBS values was 15%. conclusion: QBS according to this method is a relatively simple procedure that might contribute to objective evaluation of therapeutic effects in skeletal metastases, although its validity must be tested in a larger clinical material.

2000-03-01

299

Quantitative bone scintigraphy. A methodological evaluation in prostate cancer  

International Nuclear Information System (INIS)

Purpose: To evaluate a simple method for quantification of focal activity in bone scintigraphy (BS). Material and methods: The gamma camera was calibrated using a phantom. Quantitative bone scintigraphy (QBS) was performed on 11 men recently diagnosed with prostate cancer (PCa), for whom routine BS showed involvement of the skeleton. Following endocrine therapy for 4 to 8 months, a second QBS was performed. Changes in QBS values were then compared to changes in serum levels of prostate-specific antigen (PSA). Results: PSA response indicating regression of PCa was accompanied by a decrease in the QBS value in 8 of the 11 patients. The overall mean error of the QBS values was 15%. conclusion: QBS according to this method is a relatively simple procedure that might contribute to objective evaluation of therapeutic effects in skeletal metastases, although its validity must be tested in a larger clinical material

2000-03-01

300

Quantitative analysis of X-Ray Microtomography images of metal powders in the course of sintering  

Energy Technology Data Exchange (ETDEWEB)

In situ X-Ray microtomography offers new opportunities for analysing sintering mechanisms since it allows 3D observation of the microstructural evolution of the powder all along a sintering cycle. With synchrotron radiation at ESRF, a 3D image with a resolution of 2 {mu}m can be obtained in about one minute. In addition to the visual examination of the images, relevant microstructural parameters can be measured through quantitative image analysis using recently developed tools. In this paper the results obtained with two materials, loose copper powder and compacted steel powder, are resumed. For copper powder, the dispersion of local parameters such as particle co-ordination number and porosity is investigated. Concerning steel compacts, data about pore morphology evolution and on local strains provides clues for understanding the anisotropic shrinkage of such compacts. (authors)

2005-07-01

301

Quantitative Computed Tomography (QCT) of vertebral spongiosa. Evaluation of a possible method for managment of postmenopausal osteoporosis (PMO)  

International Nuclear Information System (INIS)

A Quantitative Computed Tomography (QCT) method, simplifying the well-known technique proposed by Genant (1982) and applied to a standard third generation whole body CT scanner is described. This technique was applied in the measurement of the trabecular bone which has high sensitivity for metabolic changes. The BMC (Bone Mineral Content) measured in different groups of subjects (healthy postmenopausal patients versus women with postmenopausal osteoporosis) showed a highly significant difference (p<0.001). The precision of repositioning (coefficient of variation 1.8% to 2.3%, obtained in healty male patients) and the good, linear relationship computed from the phantom values, minimize measurement errors. Since this method is quickly applied and involves low-dose radiation-exposure, it could be introduced in the clinical study of metabolic bone diseases.

1987-01-01

302

NEXAFS microscopy of polymeric materials: Successes and challenges encountered when characterizing organic devices  

Energy Technology Data Exchange (ETDEWEB)

We summarize recent developments in x-ray microscopy of polymers by focusing on the characterization of organic electronic devices. The quantitative compositions of model polymer blends have been mapped at a resolution of {approx}35 nm. Since it could be inferred that these devices have structures smaller than 35 nm, quantitative compositional mapping at length scales below the present resolution limit of x-ray microscopy is required. Organic devices thus serve to both highlight the success of NEXAFS microscopy to date, but to also outline the very real need for higher spatial resolution. New approaches to create improved optics or different acquisition modalities are required if x-ray microscopy is to make sustained contributions to such an important area of research as organic devices.

2009-09-01

303

Identification and robust water level control of horizontal steam generators using quantitative feedback theory  

British Library Electronic Table of Contents (United Kingdom)

In this paper, a robust water level control system for the horizontal steam generator (SG) using the quantitative feedback theory (QFT) method is presented. To design a robust QFT controller for the nonlinear uncertain SG, control oriented linear models are identified. Then, the nonlinear system is modeled as an uncertain linear time invariant (LTI) system. The robust designed controller is applied to the nonlinear plant model. This nonlinear model is based on a locally linear neuro-fuzzy (LLNF) model. This model is trained using the locally linear model tree (LOLIMOT) algorithm. Finally, simulation results are employed to show the effectiveness of the designed QFT level controller. It is shown that it will ensure the entire designer's water level closed loop specifications.

2011-01-01

304

Finite-duration Seeding Effects in Powerful Backward Raman Amplifiers  

Energy Technology Data Exchange (ETDEWEB)

In the process of backward Raman amplification (BRA), the leading layers of the seed laser pulse can shadow the rear layers, thus weakening the effective seeding power and affecting parameters of output pulses in BRA. We study this effect numerically and also analytically by approximating the pumped pulse by the ''*-pulse'' manifold of self-similar solutions. We determine how the pumped pulse projection moves within the *-pulse manifold, and describe quantitatively the effective seeding power evolution. Our results extend the quantitative theory of BRA to regimes where the effective seeding power varies substantially during the amplification. These results might be of broader interest, since the basic equations, are general equations for resonant 3-wave interactions.

2003-07-14

305

Cottonseed feeding delivers sufficient quantities of gossypol as a male deer contraceptive  

British Library Electronic Table of Contents (United Kingdom)

To define the quantitative and qualitative effects of gossypol (GP) on deer (Cervus elaphus) semen, the animals were fed cottonseed (CS). Adult stags each received 350?g of CS for 109?days. Animals received 15?mg of gossypol per kilogram body weight per day. Quantitative and qualitative parameters of experimental ejaculates (n?=?182) were compared to ejaculates (n?=?571) of control animals (n?=?5) collected during three previous natural reproductive seasons. Ejaculate fractions were evaluated by classical methods used in domestic animals. In this paper, we show that mature male deer fed CS exhibited morphological changes and decreased motility of spermatozoa and abnormalities in spermatogenesis. Radioimmunoassay measured concentrations of various steroid hormones (T-testosterone, A4-andros...

2008-01-01

306

Correlation, hierarchies, and networks in financial markets  

CERN Document Server

We discuss some methods to quantitatively investigate the properties of correlation matrices. Correlation matrices play an important role in portfolio optimization and in several other quantitative descriptions of asset price dynamics in financial markets. Specifically, we discuss how to define and obtain hierarchical trees, correlation based trees and networks from a correlation matrix. The hierarchical clustering and other procedures performed on the correlation matrix to detect statistically reliable aspects of the correlation matrix are seen as filtering procedures of the correlation matrix. We also discuss a method to associate a hierarchically nested factor model to a hierarchical tree obtained from a correlation matrix. The information retained in filtering procedures and its stability with respect to statistical fluctuations is quantified by using the Kullback-Leibler distance.

2008-01-01

307

Combined In Vivo/In Silico Study of Mechanobiological Mechanisms During Endochondral Ossification in Bone Healing  

British Library Electronic Table of Contents (United Kingdom)

Mechanobiological theories have been introduced to illustrate the interaction between biology and the local mechanical environment during bone healing. Although several theories have been proposed, a quantitative validation using histomorphometric data is still missing. In this study, in vivo histological data based on an ovine animal experiment was quantified and used to validate bone healing simulations focussing on the endochondral ossification process. The bone formation at different callus regions (periosteal and endosteal bone at the medial and lateral side) was analyzed from in vivo data and quantitatively compared with in silico results. A histomorphometric difference was found in medial and lateral hard callus formation 3 weeks after osteotomy. However, the same amount of new bone...

2011-01-01

308

CRC handbook of NASA future missions and payloads  

Energy Technology Data Exchange (ETDEWEB)

The author presents a detailed and quantitative description of all of the programs, systems, sensors and experiments associated with the next 30 years of space endeavors by the National Aeronautics and Space Administration. Derived from the fifth issue of the NASA Space Systems Technology Model, the missions and payloads are categorized by applications area: solar system exploration, astrophysics, earth sciences, communications, space transportation and utilization of the space environment. Far-term missions are described as opportunity missions and landmark missions, for the distant future. Technology requirements are collected by discipline: power, propulsion, materials, structures, information systems, navigation, guidance and control. Payload technology requirements are organized by instrument sensing range. This information defines in quantitative terms, the opportunities and limits for future civilian space system capabilities.

1986-01-01

309

Assessment of Low Quantitative Ultrasound Values of Calcaneus in Chinese Mainland Women  

British Library Electronic Table of Contents (United Kingdom)

Calcaneus quantitative ultrasound (QUS) assessment is a safe and reliable method for evaluating skeletal status. Until now, considerable data have been accumulated on the distribution of QUS in Caucasian populations, whereas such data are still insufficient in Asian populations, especially in Chinese mainland. The present study aimed to obtain the distribution characteristic of calcaneus QUS in healthy Chinese women, and to further investigate the distribution of low bone mass by QUS stiffness index (SI). This study included 2,498 healthy Chinese females aged 10-87 yr. The QUS exhibited a characteristic mild rise and then fall pattern with increasing age. Age, body height, and weight were significant influencing factors on SI, especially age and weight. The prevalence of osteoporosis detec...

2006-01-01

310

Advanced distillation curve measurements for corrosive fluids: Application to two crude oils  

British Library Electronic Table of Contents (United Kingdom)

We have recently introduced several important improvements in the measurement of distillation curves for complex fluids. The modifications include a composition-explicit data channel for each distillate fraction (for both qualitative and quantitative analysis) and corrosivity assessment of each distillate fraction. The composition-explicit information is achieved with a new sampling approach that allows precise qualitative as well as quantitative analyses of each fraction, on the fly. We have applied the new method to a variety of fluids, including simple n-alkanes, rocket propellant, gasoline, jet fuels, and a hydrocarbon fluid made corrosive with dissolved hydrogen sulfide. In the current contribution, we present the application of the advanced distillation curve method to two samples of...

2008-01-01

311

Ab initio study on pressure-induced change of effective Coulomb interaction in superconducting yttrium  

Science.gov (United States)

Ab initio lattice dynamics based on linear response method are performed for high pressure phase of yttrium to describe electron-phonon coupling and subsequent superconducting behavior. The critical temperature Tc in fcc-Y increases monotonically with pressure up to 9.25 K at 31 GPa, which is quantitatively in excellent agreement with two quasihydrostatic experiments and is qualitatively compatible with recent experiments. The excellent agreement with experiments gives us a better understanding of the effective pseudopotential ?* as well as spectral function ?2(?)F(?) in yttrium. These results demonstrate that there exists strong electron-phonon coupling in Y within the studied pressure regime, and for lower pressure electron correlation becomes stronger. Generally, it is found that superconductivity in yttrium under pressure can be described quantitatively within standard theory of phonon-mediated superconductivity.

2010-01-01

312

A numerical study of expected accuracy and precision in Calibration-Free Laser-Induced Breakdown Spectroscopy in the assumption of ideal analytical plasma  

British Library Electronic Table of Contents (United Kingdom)

Calibration-Free Laser-Induced Breakdown Spectroscopy (CF-LIBS) has been proposed several years ago as an approach for quantitative analysis of Laser-Induced Breakdown Spectroscopy spectra. Recently developed refinement of the spectral processing method is described in the present work. Accurate quantitative results have been demonstrated for several metallic alloys. However, the degree of accuracy that can be achieved with Calibration-Free Laser-Induced Breakdown Spectroscopy analysis of generic samples still needs to be thoroughly investigated. The authors have undertaken a systematic study of errors and biasing factors affecting the calculation in the Calibration-Free Laser-Induced Breakdown Spectroscopy spectra processing. These factors may be classified in three main groups: 1) experi...

2007-01-01

313

A novel volumetric method for quantitation of titanium dioxide in cosmetics  

British Library Electronic Table of Contents (United Kingdom)

Nowadays there are many sun-protection cosmetics incorporating organic or inorganic UV filters as active ingredients. Chemically stable inorganic sunscreen agents, usually metal oxides, are widely employed in high-SPF (sun protection factor) products. Titanium dioxide is one of the most frequently used inorganic UV filters. It has been used as a pigment for a long period of cosmetic history. With the development of micronization techniques, it has become possible to incorporate titanium dioxide in sunscreen formulations without the previous whitening effect, and hence its use in cosmetics has become an important research topic. However, there are very few works related to quantitation of titanium dioxide in sunscreen products. In this research, we analysed the amounts of titanium dioxide i...

2007-01-01

314

The Dynamic Analog Scale: A generic method for single-item measurement  

British Library Electronic Table of Contents (United Kingdom)

The Dynamic Analog Scale (DAS) is introduced as a technique for generating single-item measures of personality traits. The DAS is comprised of extensive trait definitions and an analog scale on which respondents simultaneously rate themselves and others. In two studies the Big Five personality traits were assessed with the DAS and compared to a multiple-item questionnaire that measured the same traits. Statistical analysis supported the validity of the DAS for predicting self-reported behavioral acts, drinking behaviors, affect, and religiosity in ways similar to the multiple-item questionnaire. Consistent with previous research, both studies supported the viability of measuring personality traits with single items.

2011-01-01

315

On the Generation of a Robust Residual for Closed-loopControl systems that Exhibit Sensor Faults  

DEFF Research Database (Denmark)

This paper presents a novel design methodology, based on shaping the system frequency response, for the generation of an appropriate residual signal that is sensitive to sensor faults in the presence of model uncertainty and exogenous unknown (unmeasured) disturbances. An integrated feedback controller design and robust frequency-based fault detection approach is proposed for Single-Input/Single-Output systems. The effciency of the proposed method is demonstrated on a Single Machine Innite Bus (SMIB) power system that achieves a coordinate power system stabilizer with satisfactory sensor fault detection capabilities.

2007-01-01

316

Luminescent lanthanide-ion doped nanoparticles as single-biomolecule labels and oxidant sensors  

Science.gov (United States)

We report on the single-particle properties of lanthanide-ion doped oxide nanoparticles. We have demonstrated that their size can be accurately determined from their luminosity. The optically determined size distribution is in very good agreement with the distribution obtained from transmission electron microscopy (TEM). We also showed that the photobleaching of these nanoparticles is related to a reduction process and that we can use it to sense in a concentration-dependent manner the presence of an oxidant like H2O2. Finally, we propose a way to perform nanoparticle-protein coupling and to determine the protein-nanoparticle ratio at the single-particle level.

2007-02-01

317

In-place testing of HEPA filter systems by the single-particle, particle-size spectrometer method  

Energy Technology Data Exchange (ETDEWEB)

This standard describes the procedure and equipment for in-place testing of HEPA filter systems by the single-particle, particle-size (SPPS) spectrometer method. This method provides the capability for evaluating the effectiveness (i.e., decontamination factor or DF) of systems consisting of one or more stages of HEPA filters against submicrometer aerosols in discrete particle-size ranges. It is particularly useful for testing of multi-stage HEPA filter installations and for testing of very large (50,000 cfm installed capacity) single-stage systems where it is desired to minimize the quantity of challenge aerosol required.

1981-12-01

318

Implantation of single-impurity Fe and its magnetic coupling in Er studied by TDPAD  

Energy Technology Data Exchange (ETDEWEB)

Single Fe impurities were implanted in an Er single crystal and found to occupy both substitutional and interstitial sites, below a temperature of 200 K. The local susceptibility of Fe on both sites follows a Curie-Weiss law and exhibits a positive local Curie constant, indicating an antiferromagnetic coupling between the Fe and the surrounding Er moments. The corresponding nuclear spin relaxation rates follow a Korringa law as a function of temperature, confirming the dominance of local magnetism and the formation of local moments on each of the sites occupied by Fe.

2004-05-01

319

Gender gap in maths test scores in South Korea and Hong Kong: Role of family background and single-sex schooling  

British Library Electronic Table of Contents (United Kingdom)

In many industrialised societies, women remain underrepresented in the sciences, which can be predicted by the gender gap in math achievement at school. Using PISA 2006 data, we explore the role of family background and single-sex schooling in girls' disadvantage in maths in South Korea and Hong Kong. This disadvantage is found to be associated with single-sex schooling, but not with family background. Attending a girls' school confers a benefit only in South Korea, whereas the gendered curriculum counteracts the selectivity advantage of girls' schools in Hong Kong. We find that a gendered social structure prevalent in both societies.

2012-01-01

320

Deterministic loading of individual atoms to a high-finesse optical cavity  

CERN Document Server

Individual laser cooled atoms are delivered on demand from a single atom magneto-optic trap to a high-finesse optical cavity using an atom conveyor. Strong coupling of the atom with the cavity field allows simultaneous cooling and detection of individual atoms for time scales exceeding 15 s. The single atom scatter rate is studied as a function of probe-cavity detuning and probe Rabi frequency, and the experimental results are in good agreement with theoretical predictions. We demonstrate the ability to manipulate the position of a single atom relative to the cavity mode with excellent control and reproducibility.

2007-01-01

321

X-ray Emission as a Probe of the Wind-Driven Shock in WR 140  

Science.gov (United States)

single star evolution. To understand the evolution of massive stars and their role in shaping the galaxy, understanding of the distribution of ...

322

Type II Quantum Computing With Superconductors.  

Science.gov (United States)

The results of this research centered on the experimental studies of a single superconducting persistent current qubit, the implementation of type-II algorithms using these qubits, and the proposal for adiabatic quantum computing using these qubits. The m...

2004-01-01

323

The burden of genetically determined eye disease.  

UK PubMed Central (United Kingdom)

We determined the underlying aetiology of blindness for the registered blind population of the Province of Newfoundland and Labrador. In both 1981 and 1984 single-gene disorders accounted for 30% of...Full Text Available

1986-09-01

324

The Heart Failure Epidemic  

UK PubMed Central (United Kingdom)

Heart failure has been singled out as an emerging epidemic, which could be the result of increased incidence and/or increased survival leading to increased prevalence. Knowledge of the responsibility...Full Text Available

2010-04-01

325

Tensions of network security and collaborative work practice: Understanding a single sign-on deployment in a regional hospital  

British Library Electronic Table of Contents (United Kingdom)

Background: Healthcare providers and their IT staff, working in an effort to balance appropriate accessibility with stricter security mandates, are considering the use of a single network sign-on approach for authentication and password management. Single sign-on (SSO) promises to improve usability of authentication for multiple-system users, increase compliance, and help curb system maintenance costs. However, complexities are introduced when SSO is placed within a collaborative environment. These complexities include unanticipated workflow implications that introduce greater security vulnerability for the individual user. Objectives and methodology: In this work, we examine the challenges of implementing a single sign-on authentication technology in a hospital environment. The aim of the...

2011-01-01

326

Sun rises on station era - Johnson Space Center - NASA  

Science.gov (United States)

Dec 4, 1998 ... throwing a single switch to as complex as the Spartan deploy and retrieve. ...... The camera, called the Acousto-Optic ...

327

Smokeless Propellants as Vehicle Borne IED Main Charges ...  

Science.gov (United States)

... detonation velocity of single base and double base propellants is investigated using two types ofignititor; an exploding bridgewire detonator with C4 ...

2011-05-14

330

Single Manager for DoD Military Working Dog Program  

Science.gov (United States)

... C. DEFINITION Military Working Dogs. Dogs that are required by the using Dol) Component for a specific purpose, mission, or combat capability. ...

1983-09-07

331

SIM: Stellar Astrophysics - SIM - NASA  

Science.gov (United States)

... and one near-main-sequence star, which will stringently constrain calculations of single-star evolution at high metallicity. Independent of SIM Lite observations ...

332

Optical and Structural Characteristics of Heavily Boron ...  

Science.gov (United States)

... Abstract : Cadmium telluride single crystals were subjected to multiple-energy boron ion implants with total doses up to 1.5 x 10 sq cm. ...

1988-05-24

333

New Frontiers in Binary Stars: Science at High Angular ...  

Science.gov (United States)

... interacting systems in which common-envelope evolutionary effects make it hard to generalize the results to single-star evolution, although they ...

2011-05-15

334

Neurocysticercosis  

UK PubMed Central (United Kingdom)

A single enhancing lesion in the brain parenchyma, also called an inflammatory granuloma, is a frequent neurologic diagnosis. One of the commonest causes of this lesion is human neurocysticercosis,...Full Text Available

2010-08-17

335

NASA Center - NASA Technical Reports Server  

Science.gov (United States)

telluride single crystals. NASA Center: NASA (Unspecified Center) Publication Year: 1966. Document ID: 19670033153. Accession Number: 67A11882 ...

336

MEDICAL FINAL REVIEW MEMORANDUM OF ORIGINAL BLA  

Science.gov (United States)

... The AAT Z mutation involves a single amino acid substitution (glutamine for lysine) at position 342, resulting in abnormal folding and polymerization of the ...

337

Laparoendoscopic single-site (LESS) retroperitoneal adrenalectomy using a homemade single-access platform and standard laparoscopic instruments  

British Library Electronic Table of Contents (United Kingdom)

Background This study aimed to evaluate laparoendoscopic single-site (LESS) adrenalectomy via the retroperitoneal approach using the Alexis wound retractor with standard laparoscopic instrumentation. Methods Since October 2009, seven LESS retroperitoneal adrenalectomies have been completed successfully with a homemade single port created using an Alexis wound retractor as an access platform through a 3-cm incision beneath the tip of the 12th rib. Results All the LESS procedures for these seven patients with adrenal tumors (size, 1.3?6.0?cm; 4 right, 1 left) were completed successfully without traditional laparoscopic conversion or complication. The average operative time was 159?min, and the estimated blood loss was 100?ml. The average hospital stay was 2?days (range, 1?3?days). Conclusion...

2011-01-01

338

Kepler: Transit Detection - Kepler - NASA  

Science.gov (United States)

Nov 12, 2010 ... The adaptive, nonparametric matched filter algorithm suggested by Kay ... For the point design of a 4 sigma single event SNR the combined NR ...

339

Haplochromis fasciatus  

Science.gov (United States)

... from a single location. The growing cities of Matadi and Boma and maritime transportation, and the potential ... known only from the Lower Congo River, between Matadi and Boma. (click...

340

Going beyond panaceas  

UK PubMed Central (United Kingdom)

In the context of governance of human–environment interactions, a panacea refers to a blueprint for a single type of governance system (e.g., government ownership, privatization, community property)...Full Text Available

2007-09-25

341

Genomics of human longevity  

UK PubMed Central (United Kingdom)

In animal models, single-gene mutations in genes involved in insulin/IGF and target of rapamycin signalling pathways extend lifespan to a considerable extent. The genetic, genomic and epigenetic influences...Full Text Available

2011-01-12

342

GERT" GRAPHICAL EVALUATION AND REVIEW TECHNIQUE  

Science.gov (United States)

of a stochastic network can be a. PERT-type network. After the terminal countdown, ...... pictorial representation of a single channel queueing system ...

344

ELECTRICAL AND OPTICAL PROPERTIES OF LEAD-TIN ...  

Science.gov (United States)

... Abstract : Single crystals of Pb(x)Sn(1-x)Te alloy have been grown with o = or thin film evaporator. ...

1969-09-03

345

Collaborative Research and Development (CR&D). Delivery ...  

Science.gov (United States)

... 7 Page 11. Figure 5. Diffraction pattern shown a and ~ slip directions with the associated misalignment for single colonies of Ti6242 [2]. 8 Page 12. -- ...

2005-10-01

346

Charting the Uncharted Waters - SIM - NASA  

Science.gov (United States)

gently constrain calculations of single-star evolution at high metallicity. Independent of SIM Lite observa- tions, we also propose to establish 4) how to ...

347

Calibrating Cosmological Chronometers: White Dwarf Masses ...  

Science.gov (United States)

... The second scenario is limited by the age of our Galaxy such that the lowest-mass WD that could be formed via single star evolution is ~0.47 M ...

2011-05-14

348

Binary stars - A look at some interesting ... - GISS Publications - NASA  

Science.gov (United States)

... each star goes. The results of (1) are compared with predictions based on (2) and on single star evolution theory to discover the various stages which occur. ...

349

Battery Prognostics - Motivation - Intelligent Systems Division - NASA  

Science.gov (United States)

The rate of battery use is sometimes even higher in military operations. During Operation Iraqi Freedom, the Marines used more than 3000 single-use ...

350

An efficient quantum secure direct communication scheme with authentication  

Science.gov (United States)

In this paper an efficient quantum secure direct communication (QSDC) scheme with authentication is presented, which is based on quantum entanglement and polarized single photons. The present protocol uses Einstein-Podolsky-Rosen (EPR) pairs and polarized single photons in batches. A particle of the EPR pairs is retained in the sender's station, and the other is transmitted forth and back between the sender and the receiver, similar to the ``ping-pong'' QSDC protocol. According to the shared information beforehand, these two kinds of quantum states are mixed and then transmitted via a quantum channel. The EPR pairs are used to transmit secret messages and the polarized single photons used for authentication and eavesdropping check. Consequently, because of the dual contributions of the polarized single photons, no classical information is needed. The intrinsic efficiency and total efficiency are both 1 ...

2007-07-01

351

An Algorithmic Solution for a Queueing Model of a Computer ...  

Science.gov (United States)

... time the terminal becomes active and begins the process of ... The model class considered here is of a single server queueing ... 1 I are both stochastic. ...

1981-01-01

352

Alpha-toxin of Staphylococcus aureus.  

UK PubMed Central (United Kingdom)

Alpha-toxin, the major cytotoxic agent elaborated by Staphylococcus aureus, was the first bacterial exotoxin to be identified as a pore former. The protein is secreted as a single-chain, water-soluble...Full Text Available

1991-12-01

353

Abt Single-Sided Body Template - NASA  

Science.gov (United States)

development of strategic partnerships, and sustainability. ...... http://eo.msfc .nasa.gov/smsp.html#mikem (accessed 9/15/09); ...

355

A cost of energy comparison of single and multi cavity solar central receiver systems  

Energy Technology Data Exchange (ETDEWEB)

Variations in thermal energy costs of single module solar central receiver systems using one, two, three, and four aperture cavity receivers at a location corresponding to Barstow, California are investigated for nominal power ratings ranging from 100 MWt to 900 MWt. Also considered are the effects on energy costs of changes in plant latitude, and the energy cost impact of the replacement of the single module design with multiple connected modules producing the same thermal power. The results, obtained with the aid of the DELSOL2 computer program, indicate that solar central receiver plant energy costs are insensitive functions of power level, latitude, and configuration. No clear cost of energy advantage between single and multiple modules is seen.

1983-06-01

356

X-ray spectral microanalysis of component redistribution in finely dispersed two-phase alloys  

International Nuclear Information System (INIS)

It is shown that it is necessary to take into account locality of the analysis and to introduce additional corrections for partial capture of matrix and fluorescent subexcitation by matrix during quantitative X-ray spectral microanalysis of finely dispersed materials. Cast two-phase (#alpha#+#beta#) titanium alloy VT3-1 is chosen as an investigation object.

357

Wind ripple analysis  

Science.gov (United States)

Efficient and economical utilization of wind power will require the ability to measure and ultimately predict the effects fluctuations in the incident wind will have on a wind turbine. In order to quantitatively assesss these effects, experimental techniques have been developed which allow analysis of full-scale performance of wind turbines with particular emphasis on the effects caused by turbulence in the incident wind. Examples of these techniques are presented using data from the DOE/Sandia Vertical Axis Wind Turbine (VAWT) program.

1981-01-01

358

Topological excitations and second order transitions in 3D O(N) models  

Energy Technology Data Exchange (ETDEWEB)

I discuss several examples of critical phenomena in O(N) models where topological excitations play an important role at criticality. I focus particular attention on the O(2) model in 3D, where recent measurements of the vortex string length distribution in equilibrium suggest the existence of a quantitative picture of the critical behavior in terms of defects. The compatibility of this perspective with renormalization group predictions is examined.

2001-01-01

359

Theoretical studies of Cerro Prieto brines chemical equilibria  

Energy Technology Data Exchange (ETDEWEB)

A chemical equilibrium model is used, implemented in a compact FORTRAN package called HITEQ, to investigate possible mineral deposition related to prereinjection treatment of Cerro Prieto brines for silica removal. Large saturation ratios of the treated brines with respect to several minerals are indicated by these computations. As a remedy, an inexpensive CO/sub 2/ removal scheme aimed at inhibiting carbonate mineral precipitation is proposed. This scheme is quantitatively discussed with the aid of HITEQ. It is concluded that the proposed treatment is both technically and economically feasible.

1980-02-01

360

The Phenomics and Expression Quantitative Trait Locus Mapping of Brain Transcriptomes Regulating Adaptive Divergence in Lake Whitefish Species Pairs (Coregonus sp.)  

UK PubMed Central (United Kingdom)

We used microarrays and a previously established linkage map to localize the genetic determinants of brain gene expression for a backcross family of lake whitefish species pairs (Coregonus sp.). Our...Full Text Available

2008-09-01

361

Terms Beginning With \\  

Wastenet

... Risk (Adverse) for Endangered Species: Risk to aquatic species if anticipated pesticide residue levels equal one-fifth of LD10 or one-tenth of LC50; risk to ...terrestrial species if anticipated pesticide residue levels equal one-fifth of LC10 or one-tenth of LC50. Risk Assessment: Qualitative and quantitative evaluation of the ... Risk for Non-Endangered Species: Risk to species if anticipated pesticide residue levels are equal to or greater than LC50. Risk Management: The process ...

362

Structure of fragment energy spectra in spontaneous fission of sup 242 Cm and fast-neutron fission of sup 242 m Am  

Energy Technology Data Exchange (ETDEWEB)

A technique for measurement of the energy spectra of fission fragments is discussed. The fine structure found in the spectra of fragments from spontaneous fission of {sup 242}Cm and fast-neutron fission of {sup 242{ital m}}Am is analyzed. The quantitative parameters of the structure and their analogy with the characteristics of cold fission are discussed.

1989-05-01

363

Spectrophotometric technique quantitatively determines NaMBT inhibitor in ethylene glycol-water solutions  

Science.gov (United States)

Spectrophotometric method, using a ratio-recording ultraviolet-absorption spectrophotometer, permits analysis of NaMBT in ethylene glycol-water solutions with high accuracy. It reduces analysis time, requires smaller samples, and is able to detect extremely small concentrations of mercaptobenzothiazole.

1967-01-01

364

Spatiotemporal Analysis of Environmental Radioactivity in Soil around Nuclear Plant  

Energy Technology Data Exchange (ETDEWEB)

Geostatistical techniques make it possible to qualitatively and quantitatively analyze spatiotemporal inherent characteristics of environmental radiation or radioactivity. Spatial patterns and trend analysis of environmental radioactivity, e.g., {sup 137}Cs and {sup 40}K, in soil around nuclear facilities (Kori, Wolsung, Yeonggwang, Uljin, and Daejeon) will be investigated and discussed.

2006-07-01

365

Some insights from total collapse  

CERN Document Server

We discuss the Sundman-Weierstrass theorem of total collapse in its historical context. This remarkable and relatively simple result, a type of stability criterion, is at the crossroads of some interesting developments in the gravitation Newtonian N-body problem. We use it as motivation to explore the connections to such important concepts as integrability, singularities and tyipicality in order to gain some insight on the transition from a predominantly quantitative to a novel qualitative approach to dynamical problems that took place at the end of the 19th century.

2008-01-01

366

SIV antigen immunization induces transient antigen-specific T cell responses and selectively activates viral replication in draining lymph nodes in retroviral suppressed rhesus macaques  

UK PubMed Central (United Kingdom)

BackgroundHIV infection causes a qualitative and quantitative loss of CD4+ T cell immunity. The institution of anti-retroviral therapy (ART) restores CD4+ T...Full Text Available

367

Risk orientated analysis of the SNR 300  

International Nuclear Information System (INIS)

To make a quantitative comparison of risks between the SNR 300 and a modern PWR (Biblis B), the consequences of an accident or the extent of damage of a release of radionuclides to the environment due to an accident are estimated by computer programs for accident consequence models. The accident analysis includes an analysis of events for Bethe-Tait accidents with failure of the outer containment. The FGSB release rates are compared with those of the Society for Reactor Safety (GRS). (HP).

368

Quantitative x ray microanalysis of pulmonary mineral particles in a patient with pneumoconiosis and two primary lung tumours.  

UK PubMed Central (United Kingdom)

The right upper lung lobe of a 74 year old man was resected for a central tumour. Two primary cancers were found; a central small cell carcinoma and a peripheral squamous cell carcinoma. In addition,...Full Text Available

1984-11-01

369

Quantitative transfer of the molybdenum cofactor from xanthine oxidase and from sulphite oxidase to the deficient enzyme of the nit-1 mutant of Neurospora crassa to yield active nitrate reductase.  

UK PubMed Central (United Kingdom)

An assay method is described for measurement of absolute concentrations of the molybdenum cofactor, based on complementation of the defective nitrate reductase ('apo nitrate reductase') in extracts...Full Text Available

1984-04-15

370

Quantitative spectroscopy of close binary stars  

CERN Document Server

The method of spectral disentangling has now created the opportunity for studying the chemical composition in previously inaccessible components of binary and multiple stars. This in turn makes it possible to trace their chemical evolution, a vital aspect in understanding the evolution of stellar systems. We review different ways to reconstruct individual spectra from eclipsing and non-eclipsing systems, and then concentrate on some recent applications to detached binaries with high-mass and intermediate-mass stars, and Algol-type mass-transfer systems.

2011-01-01

371

Quantitative evaluation of simultaneous reconstruction with model-based crosstalk compensation for 99mTc?123I dual-isotope simultaneous acquisition brain SPECT  

UK PubMed Central (United Kingdom)

A model-based method has been previously developed to estimate and compensate for the crosstalk and downscatter contamination in simultaneous 123I∕99mTc dual-isotope SPECT...Full Text Available

2009-06-01

372

Quantitative electron-paramagnetic-resonance measurements of the electron-transfer components of the photosystem-I reaction centre. The reaction-centre chlorophyll (P700), the primary electron acceptor X and bound iron-sulphur centre A.  

UK PubMed Central (United Kingdom)

An e.p.r. spectrum of the reduced form of the electron-transport component (X), thought to be the primary electron acceptor of Photosystem I, was obtained. By using line-shape simulations of this component...Full Text Available

1978-02-15

373

Quantitative and empirical demonstration of the Matthew effect in a study of career longevity  

UK PubMed Central (United Kingdom)

The Matthew effect refers to the adage written some two-thousand years ago in the Gospel of St. Matthew: “For to all those who have, more will be given.” Even two millennia later, this...Full Text Available

2011-01-04

374

Quantitative Trait Loci for Grain Yield and Adaptation of Durum Wheat (Triticum durum Desf.) Across a Wide Range of Water Availability  

UK PubMed Central (United Kingdom)

Grain yield is a major goal for the improvement of durum wheat, particularly in drought-prone areas. In this study, the genetic basis of grain yield (GY), heading date (HD), and plant height (PH) was...Full Text Available

2008-01-01

375

Quantitative 31P NMR Spectroscopy and 1H MRI Measurements of Bone Mineral and Matrix Density Differentiate Metabolic Bone Diseases in Rat Models  

UK PubMed Central (United Kingdom)

In this study, bone mineral density (BMD) of normal (CON), ovariectomized (OVX) and partially nephrectomized (NFR) rats was measured by 31P NMR spectroscopy; bone matrix density was...Full Text Available

2010-06-01

376

Quantitation of transcribing native simian virus 40 minichromosomes extracted from CV1 cells late in infection.  

UK PubMed Central (United Kingdom)

Simian virus 40 transcriptional complexes could be extracted from CV1 cells late in infection and separated from the bulk of inactive viral chromatin. Sucrose gradient sedimentation, cesium sulfate...Full Text Available

1981-04-01

377

Principles of the coprecipitation of thorium and yttrium with organicinorganic salts of molybdenum polyacids  

Energy Technology Data Exchange (ETDEWEB)

This paper advances hypotheses on the chemistry of the interaction of thorium and yttrium with organic-inorganic salts of molybdenum polyacids. On the basis of an analysis of the data of an adsorption experiment and the quantitative relationships that follow from the law of mass action, it is shown that thorium is absorbed by the solid phase by coprecipitation with the participation of complex formation, while the coprecipitation of yttrium with salts of polyacids is due to a reaction of ion exchange chemisorption.

1986-03-01

378

Phenomenological combustion model for a quiescent chamber diesel engine  

Energy Technology Data Exchange (ETDEWEB)

A phenomenological model is presented for prediction of the combustion characteristics of a quiescent chamber diesel engine. Predictions with the model have shown acceptable agreement with a range of experimental data. The major physical processes controlling combustion have been characterized, and the dominant role of air entrainment and turbulent mixing confirmed quantitatively. 45 refs.

1981-10-01

379

Ozone hazards incurred in #gamma#-plant operation  

International Nuclear Information System (INIS)

The irradiation of air produces some toxic gases such as ozone, nitric oxide, nitrogen dioxide, nitrogen trioxide, nitrogen tetroxide, nitric anhydride and nitrous oxide. Of these gases, ozone is the most important because of its toxicity and may be produced in such quantities as to constitute a health hazard within the irradiation room. The toxicity, and explosive characteristics of ozone and quantitative aspects of ozone production are discussed and ventilation requirements considered. (U.K.).

380

On the CSFT approach to localized closed string tachyons  

Energy Technology Data Exchange (ETDEWEB)

We compute the potential for localized closed string tachyons in bosonic string theory on the orbifold C/Z{sub 4} using level-truncated closed string field theory. The critical points of the potential exhibit features which agree with their conjectured identification as lower-order orbifolds. However this case also raises some questions regarding the quantitative predictions associated with these conjectures. (author)

2005-01-01

381

Nonformity of the electron density in amorphous silicon films  

Energy Technology Data Exchange (ETDEWEB)

The authors study the nonuniformity of a-Si:H films obtained by the method of vacuum condensation, with the help of x-ray small-angle scattering (SLS) and transmission electron microscopy. Films of hydrogenated amorphous silicon are greatest interest, because the electronic properties of this material can be controlled by doping. As a result of the compensation of the ruptured bonds, and possibly, effects of melting, the properties of such films are analogous to those of singlecrystalline silicon. XLS enables a quantitative determination of the prameters of the regions of low electron density (RLD) in such objects.

1985-12-01

382

Methods and results of gas chromatographicmass spectrometric determination of volatile organic substances in an urban atmosphere  

Energy Technology Data Exchange (ETDEWEB)

The method and results of the quantitative gas chromatographic determination of volatile organic substances in an urban atmosphere are presented. The concentration of organic substances was determined by using a mixed adsorber consisting of graphitized thermal carbon black and activated charcoal modified by pyrocarbon. Average, maximum and minimum concentrations of constant organic components in the atmosphere of Leningrad as a typical large industrial city are reported.

1983-01-01

383

Mathematical and physical model of steam-water mixture flow in horizontal steam generator  

International Nuclear Information System (INIS)

A mathematical and physical model was constructed describing the hydrodynamics of the two-phase mixture in the horizontal steam generator. The HP 9830 A desk-top calculator was used for the computations. The output variable of the solution was the level shape. A quantitative and qualitative comparison was made of the results of computations and experimental data. (author).

1982-10-01

384

Magnetic resonance imaging of stents. Quantitative in vitro examination at 3 Tesla; Magnetresonanztomographie von Stents. Quantitative MR-Untersuchungen in vitro bei 3 Tesla  

Energy Technology Data Exchange (ETDEWEB)

The aim of this study was to qualitatively and quantitatively study MR artifacts of various stents on the basis of in vitro experiments. We were particularly interested whether sequence type and orientation of the stent with respect to the static magnetic field influences the artifact. We examined 18 stents of different material (nitinol, stainless steel, cobalt alloy), different design of the stent meshes (AccuLink, OmniLink, DynaLink, Xact, Protoge, Wallstent Monorail), different diameter (5-10 mm) and different length (18-58 mm) with a turbo spin echo (TSE), a 2D-fast low angle shot (FLASH) and a 3D-FLASH sequence. The MR images were examined qualitatively with respect to possible artifacts. Furthermore we examined the MR data quantitatively: The contrast-noise-ratio (CNR) was determined both within the stent and outside (within the tube); based on these values we calculated the transparency factor P, furthermore we calculated the apparent ...

2009-07-01

385

Kinetic Parameters of Efflux of Penicillins by the Multidrug Efflux Transporter AcrAB-TolC of Escherichia coli?  

UK PubMed Central (United Kingdom)

The multidrug efflux transporter AcrAB-TolC is known to pump out a diverse range of antibiotics, including β-lactams. However, the kinetic constants of the efflux process, needed for the quantitative...Full Text Available

2010-05-01

386

Internal emitter limits for iodine, radium and radon daughters  

Energy Technology Data Exchange (ETDEWEB)

This paper identifies some of the issues which arise in the consideration of the derivation of new limits on exposure to internal emitters. Basic and secondary radiation protection limits are discussed. Terms are defined and applied to the limitation of risk from stochastic effects. Non-stochastic data for specific internal emitters (/sup 131/I and the radium isotopes) are presented. Emphasis is placed on the quantitative aspects of the limit setting problem. 65 references, 2 figures, 12 tables.

1984-08-15

387

Increased bone radiotracer uptake in renal osteodystrophy  

Energy Technology Data Exchange (ETDEWEB)

Bone radiotracer uptake in renal osteodystrophy was investigated in 35 dialysis patients by correlating the results of quantitative bone scintigraphy with those of biochemical and bone morphometric studies. There were highly significant correlations (P < 0.001) between the total skeletal activity and the biochemical (iPTH and alkaline phosphatase), and histologic parameters of hyperparathyroidism. These clinical results strongly suggest that increased bone turnover i.e. hyperparathyroidism, rather than osteomalacia is the major cause of increased skeletal uptake in renal osteodystrophy.

1982-04-01

388

In Pursuit of Spreadsheet Excellence  

CERN Document Server

The first fully-documented study into the quantitative impact of errors in operational spreadsheets identified an interesting anomaly. One of the five participating organisations involved in the study contributed a set of five spreadsheets of such quality that they set the organisation apart in a statistical sense. This virtuoso performance gave rise to a simple sampling test - The Clean Sheet Test - which can be used to objectively evaluate if an organisation is in control of the spreadsheets it is using in important processes such as financial reporting.

2008-01-01

389

Genetic and somatic risks in X-ray diagnosis  

International Nuclear Information System (INIS)

Based on a literature study an actual summary of the risk-utility problems in X-ray diagnosis is outlined due to the Recommendations of the International Commission for Radiation Protection (ICRP publication 26/1977). Papers demonstrating quantitative assessment of the somatic and genetical risk in X-ray examination are preferably cited and evaluated. It is concluded that the somatic and genetical risk is low in diagnostic ratiology. However, it must not be neglected and has always to be compared to the utility of an examination as well as to other risks of the examination. (author).

1982-01-01

390

Free convection heat and mass transfer to steady flow in a semi-infinite vertical porous medium  

Science.gov (United States)

Analytical solutions are derived for a flow in a semi-infinite vertical porous medium with heat and mass transfer. When the temperature and mass concentration are uniform a constant pressure is possible and sustains a fully developed flow. Thereafter there is a small perturbation on the wall temperature and concentration and the subsequent two-dimensional problem is tackled for a large Prandtl number, free convection parameters and small Reynolds number. The heat transfer rate at the wall is discussed quantitatively.

1988-02-01

391

Effect of resin size on HETP in separation of isotopes by chromatography  

Energy Technology Data Exchange (ETDEWEB)

In this report, the quantitative relation between the height equivalent to a theoretical plate (HETP) and the size of ion exchange resin is studied by enriching lithium isotopes with high pressure ion exchange displacement chromatography. The dependence of HETP on the size of the resin can be expressed as H = C x (anti r)sup( ) in which = 2.4 and it is found that Snyder's equation is suitable for such a system of isotope separation as may be explained by the simple displacement mechanism.

1985-02-01

392

Domain structure of ferrite-garnet crystalline plates (111) with uniaxial anisotropy  

Energy Technology Data Exchange (ETDEWEB)

Magnetic field, thickness and magnetic forming effect on general mode and quantitative parameters of the domain structure (DS) of ferrite-garnet (EuEr)/sub 3/(FeGa)/sub 5/O/sub 12/ monocrystalline plates (111) is investigated. Field interval of circle (cone) and ring domain stability is determined. It is shown that DS of ferrite-garnet crystals with uniaxial an6sotropy has some peculiarities, that can be explained by cubic anisotropy effect.

1982-03-01

393

Distribution of Indole-3-Acetic Acid and the Occurrence of Its Alkali-Labile Conjugates in the Extraxylary Region of Pinus sylvestris Stems 1  

UK PubMed Central (United Kingdom)

Free and conjugated indole-3-acetic acid (IAA) were measured by quantitative gas chromatography-selected ion monitoringmass spectrometry in the extraxylary region of the stem of large Pinus...Full Text Available

1990-08-01

394

Development and application of a gamma scanning system for LLW and MLW packages  

International Nuclear Information System (INIS)

The report describes the studies carried out to design a non-destructive system for the radiological characterization of packages containing LLW and MLW. This technique is applied for quantitative and qualitative gamma emitters determination in packages with homogeneous and heterogeneous matrices as well as the development of a maximum activity points location system. Development involves also the automatization for its industrial use.

1993-09-05

395

Determination of Mn, Fe, Ni, Cu, Zn and Pb contents in samples of apple trees by radionuclide X-ray fluorescence analysis  

Energy Technology Data Exchange (ETDEWEB)

The applicability of the radionuclide X-ray fluorescence analysis (RXFA) for qualitative and quantitative evaluation of environmental plant samples is discussed and examples of determination of Mn, Fe, Ni, Cu, Zn, Pb in samples of apple trees are given. The instrumentation, the standard and sample preparation are also presented.

1982-12-01

396

Composting - environmentally compatible waste disposal - one of the incredients of waste management  

Energy Technology Data Exchange (ETDEWEB)

Considering the fact that more than 40% of all household wastes are organic wastes composting could be an excellent relief and complement to other waste disposal methods (e.g. combustion or direct landfills). Provided the right conditions household wastes could be composted together with sewage sludges and manures. The paper discusses the legal aspects, quantitative evaluations, conveying systems, as well as the compost utilization and marketing aspects valid for the Federal Republic of Germany.

1988-09-20

397

Comparative study of different methodologies for quantitative rock analysis by Laser-Induced Breakdown Spectroscopy in a simulated Martian atmosphere  

Energy Technology Data Exchange (ETDEWEB)

Laser-Induced Breakdown Spectroscopy was selected by NASA as part of the ChemCam instrument package for the Mars Science Laboratory rover to be launched in 2009. ChemCam's Laser-Induced Breakdown Spectroscopy instrument will ablate surface coatings from materials and measure the elemental composition of underlying rocks and soils at distances from 1 up to 10 m. The purpose of our studies is to develop an analytical methodology enabling identification and quantitative analysis of these geological materials in the context of the ChemCam's Laser-Induced Breakdown Spectroscopy instrument performance. The study presented here focuses on several terrestrial rock samples which were analyzed by Laser-Induced Breakdown Spectroscopy at an intermediate stand-off distance (3 m) and in an atmosphere similar to the Martian one (9 mbar CO{sub 2}). The experimental results highlight the matrix effects and the measurement inaccuracies due to the noise accumulated ...

2006-03-15

398

Comparative study of different methodologies for quantitative rock analysis by Laser-Induced Breakdown Spectroscopy in a simulated Martian atmosphere  

International Nuclear Information System (INIS)

Laser-Induced Breakdown Spectroscopy was selected by NASA as part of the ChemCam instrument package for the Mars Science Laboratory rover to be launched in 2009. ChemCam's Laser-Induced Breakdown Spectroscopy instrument will ablate surface coatings from materials and measure the elemental composition of underlying rocks and soils at distances from 1 up to 10 m. The purpose of our studies is to develop an analytical methodology enabling identification and quantitative analysis of these geological materials in the context of the ChemCam's Laser-Induced Breakdown Spectroscopy instrument performance. The study presented here focuses on several terrestrial rock samples which were analyzed by Laser-Induced Breakdown Spectroscopy at an intermediate stand-off distance (3 m) and in an atmosphere similar to the Martian one (9 mbar CO2). The experimental results highlight the matrix effects and the measurement inaccuracies due to the noise accumulated when low signals are ...

2006-03-01

399

Colorimetric porous indicator of carbon dioxide  

Energy Technology Data Exchange (ETDEWEB)

This paper investigates the spectral characteristics of three-dimensionally porous carbon dioxide indicators based on a porous silicate glass and phenolphthalein. The absorption spectra of the original solutions of phenolphthalein in alkaline and acid solutions are shown. The solutions were acidified by bubbling CO/sub 2/ through an alkaline phenolphthalein solution. The authors have succeeded in producing a reversible colorimetric adsorption indicator for carbon dioxide which after proper calibration enables the CO/sub 2/ content of an atmosphere to be estimated quantitatively.

1986-03-01

400

Bonus incensed | vox - Research-based policy analysis and commentary from leading economists  

Wastenet

... There is an evident, growing public discontent among supervisors and regulators with quantitative risk evaluation techniques, including Value-at-Risk and similar methods, so it is surprising to see the same authorities now advocating their use in more doubtful circumstances to risk weight bonuses. Deferrals and claw backs ...

401

Beyond "Little Taipei": The Development of Taiwanese Immigrant Businesses in Los Angeles.  

Science.gov (United States)

Qualitative and quantitative techniques, including a telephone survey of 310 Taiwanese business owners, were used to study the unique features of Taiwanese immigrant businesses in Los Angeles (California). When provided with entrepreneurial capital, Taiwanese enterprises grow rapidly in the context of Los Angeles's economic restructuring. (SLD)

1994-12-01

402

Beam position monitor sensitivity for low-[beta] beams  

Energy Technology Data Exchange (ETDEWEB)

Design of a beam position monitor (BPM) which is sensitive to low velo charged particle beams is considered. Quantitative estimates are made for the corrections to the conventional approximations to solutions of the Laplace Equation in two-dimensions when a BPM is used to measure to position of low velocity (low-[beta]) beams. (AIP)

1994-10-10

403

Assimilation of Remote Sensing Data into Shelf Sea Hydrodynamic Models  

Environmental Research Database

DescriptionRemote sensing of the sea surface from satellites in near-polar orbits has contributed greatly to our understanding of the links between physical and biological processes in marine systems. However most of this progress has been made in open oceanic waters or major upwelling areas, and many unresolved problems are encountered in coastal regions and shelf seas. In these optically complex waters, quantitative remote sensing requires a more sophisticated interpretation strategy than that implemente [continued...

404

Assessing the Risks of Sampling Rates for Surveilling a Population  

British Library Electronic Table of Contents (United Kingdom)

Surveillance of a population, such as a weapon stockpile, is needed to discover manufacturing defects as well as deterioration as the population ages. This article considers the risks of sampling rates for surveillance from three perspectives: detection probability of defects in a proportion of a population with pass/fail data, detection of a trend in a defective proportion of the population with pass/fail data, and detection of a trend with quantitative degradation measurements. Understanding of these risks will help the decision maker choose a sampling rate to protect against such problems of a specified size at a tolerable risk.

2011-01-01

405

Application of alpha and gamma spectroscopy to the quantitative analysis of transuranium nuclides in nuclear fuel  

International Nuclear Information System (INIS)

In nuclear fuel with a burn-up of 33 kg/t U and 52 kg/t U 15 transuranium nuclides "2"3"7Np to "2"4"6Cm have been determined by alpha and gamma spectroscopy after radiochemical separation. (author).

406

A mechanism for the degradation of superconducting transition temperatures on high energy neutron irradiation in A-15 compounds  

International Nuclear Information System (INIS)

Electron microscopic observations of neutron irradiated Nb_3Sn revealed the presence of highly disordered regions of size approximately 35 A in a much less disordered matrix. This observation is shown to provide a means of explaining quantitatively many superconducting properties of irradiated A-15 compounds. In particular Tsub(c) of the irradiated materials could be easily predicted using the mathematical formulations developed for the proximity effect. (Auth.).

407

X-ray diffraction studies of palladium silicide thin films  

Energy Technology Data Exchange (ETDEWEB)

The solid state reaction between a Pd thin film and a Si substrate produces a single new phase, Pd/sub 2/Si, for temperatures <700/sup 0/C. When the substrate is a single crystal of (111) surface orientation, this process is particularly interesting because the silicide grows epitaxially. Growth of epitaxial interfacial Pd/sub 2/Si was the focus of this study using X-ray diffraction techniques.

1985-01-01

408

Vaccination response to tetanus toxoid and 23-valent pneumococcal vaccines following administration of a single dose of abatacept: a randomized, open-label, parallel group study in healthy subjects  

UK PubMed Central (United Kingdom)

The effect of abatacept, a selective T-cell co-stimulation modulator, on vaccination has not been previously investigated. In this open-label, single-dose, randomized, parallel-group, controlled study,...Full Text Available

2007-01-01

409

Spiral modes in the diffusion of a single granular particle on a vibrating surface  

International Nuclear Information System (INIS)

We consider a particle that is subject to a constant force and scatters inelastically on a vibrating periodically corrugated floor. At small friction and for small scatterers the dynamics is dominated by resonances forming spiral structures in phase space. These spiral modes lead to pronounced maxima and minima in the diffusion coefficient as a function of the vibration frequency, as is shown in computer simulations. Our theoretical predictions may be verified experimentally by studying transport of single granular particles on vibratory conveyors.

2004-11-29

410

Single-mode 30 MW CO/sub 2/ laser system for 16. mu. m Raman scattering in parahydrogen  

Energy Technology Data Exchange (ETDEWEB)

A CO/sub 2/ laser chain able to supply approx.=30 MW on a single mode TEM/sub 00/ is described. The coupling of a modified Lumonics 101 module with a low-pressure cell constitues the oscillator and two further Lumonics 103 stages two amplifiers. The final pulse achieves the energy of 4.0 J with 90% of this energy in a peak of 100 ns FWHM.

1983-01-11

411

Single-event burnout of power MOSFET devices for satellite application  

International Nuclear Information System (INIS)

Single-event burnout (SEB) sensitivity was tested for power MOSFET devices, JTMCS081 and JTMCS062, which were made in Institute of Microelectronics, Chinese Academy of Sciences, using californium-252 simulation source. SEB voltage threshold was found for devices under test (DUT). It is helpful for engineers to choose devices used in satellites. (authors)

2008-12-01

412

Simulation aided hardening of N-channel power MOSFETs to prevent single event burnout  

International Nuclear Information System (INIS)

2D MEDICI simulator is used to investigate hardening solutions to single-event burnout (SEB). SEB parametric dependencies such as carrier lifetime reduction, base enlargement, and emitter doping decrease have been verified and a p"+ plug modification approach for SEB hardening of power MOSFETs is validated with simulations on actual device structures.

1995-07-17

413

Shaft bearing of steam turbines with large capacity  

International Nuclear Information System (INIS)

The advantages and disadvantages of single-point or double-point bearing of rotors with several single shafts are illustrated by examples from the KWU series. The design features of modern bearings are described. Some results from the test program for the development of these bearings are reported. In the last section the vibration behavior of the shafts is considered. Various phenomena - like self-excited vibrations and those caused by unbalance or the influence of partial admission - are briefly discussed. (orig.).

414

SAMFT1D: Single-phase and multiphase flow and transport in 1 dimension. Version 2.0, Documentation and user`s guide  

Energy Technology Data Exchange (ETDEWEB)

This report documents a one-dimensional numerical model, SAMFT1D, developed to simulate single-phase and multiphase fluid flow and solute transport in variably saturated porous media. The formulation of the governing equations and the numerical procedures used in the code for single-phase and multiphase flow and transport are presented. The code is constructed to handle single-phase as well as two or three-phase flow conditions using two integrated sets of computational modules. The fully implicit scheme is used in the code for both single-phase and multiphase flow simulations. Either the Crank-Nicholson scheme or the fully implicit scheme may be used in the transport simulation. The single-phase modules employ the Galerkin and upstream weighted residual finite element techniques to model flow and transport of water (aqueous phase) containing dissolved ...

1991-09-01

415

PBG structures for multi-beam devices  

International Nuclear Information System (INIS)

Photonic band gap structures with single or multiple defects show potential for use in single-beam and multi-beam klystrons and particle accelerators. The primary concerns are the coupling between the modes at each individual defect site and the damping of unwanted higher order modes. A conceptual design of a PBG based, multi-beam klystron and methods to damp HOMs and to cool and tune the structure are presented.

2002-12-12

416

Optical in situ size determination of single lanthanide-ion doped oxide nanoparticles  

Science.gov (United States)

We show that the size of a lanthanide-ion doped nanoparticle can be accurately determined from its luminosity. The optically determined size distribution is in very good agreement with the distribution obtained from transmission electron microscopy. These data confirm that single nanoparticles are visualized in microscopy experiments. Nanoparticles as small as 13 nm are detectable with integration times of 500 ms.

2006-12-01

417

On the nucleon decay of subbarrier single-particle states in soft spherical nuclei  

Energy Technology Data Exchange (ETDEWEB)

The nucleon decay of subbarrier single-particle states with large angular momentum and parity opposite to that of the shell in soft spherical nuclei is considered. It is shown that the reduced probabilities of the nucleon decay into the ground state (0{sup +}) and into the first excited (2{sup +}) state of the daughter nucleus have qualitatively different energy dependences. (orig.).

1991-06-20

418

On the nucleon decay of subbarrier single-particle states in soft spherical nuclei  

International Nuclear Information System (INIS)

The nucleon decay of subbarrier single-particle states with large angular momentum and parity opposite to that of the shell in soft spherical nuclei is considered. It is shown that the reduced probabilities of the nucleon decay into the ground state (0"+) and into the first excited (2"+) state of the daughter nucleus have qualitatively different energy dependences. (orig.).

419

Massive parallel generation of indistinguishable single photons via the polaritonic superfluid to Mott-insulator quantum phase transition  

International Nuclear Information System (INIS)

We study the possibility of utilizing the superfluid to Mott-insulator quantum phase transition in an array of quantum well exciton-polariton traps to generate indistinguishable single photons in a massive parallel fashion. By means of analytical and numerical methods, the device operations and system properties are examined using realistic experimental parameters. Such a deterministic, massive parallel generation may find new applications in photonic quantum information processing.

2010-12-01

420

Manufacture and characterization of Pb(1-x)Sn(x)Te photoconductors  

Science.gov (United States)

A general account of the properties, growing technology and annealing of lead-tin-telluride single crystals is given. Photoconductors were made for the 8 to 14 micron. spectral range and responsivity, detectivity and spectral response measurements showed satisfactory results. Improvement in the growing and annealing of the single crystals promise good performance in the near future.

1984-03-01

421

Load requirements for maintaining structural integrity of Hanford single-shell tanks during waste feed delivery and retrieval activities  

Energy Technology Data Exchange (ETDEWEB)

This document provides structural load requirements and their basis for maintaining the structural integrity of the Hanford Single-Shell Tanks during waste feed delivery and retrieval activities. The requirements are based on a review of previous requirements and their basis documents as well as load histories with particular emphasis on the proposed lead transfer feed tanks for the privatized vitrification plant.

1999-09-22

422

Features of two hepatitis B virus (HBV) DNA integrations suggest mechanisms of HBV integration.  

UK PubMed Central (United Kingdom)

Two integrated hepatitis B virus (HBV) DNA molecules were cloned from two primary hepatocellular carcinomas each containing only a single integration. One integration (C3) contained a single linear...Full Text Available

1989-06-01

423

Evaporator condensates: continuous bioprocessing of simulated sulfite condensates to produce single cell protein. [Candida utilis  

Energy Technology Data Exchange (ETDEWEB)

The continuous bioprocessing of simulated steam-stripped sulfite pulp mill evaporator condensates using Candida utilis to produce single cell protein has been studied. At 32 degrees C, processing can be conducted at space velocities of up to 0.43 hr/sup -1/ with over 90% removal of acetic acid present at an initial concentration of 2 g/liter. (Refs. 16).

1982-11-01

424

Effects of single or combined histamine H1-receptor and leukotriene CysLT1-receptor antagonism on nasal adenosine monophosphate challenge in persistent allergic rhinitis  

UK PubMed Central (United Kingdom)

BackgroundThe effects of single or combined histamine H1-receptor and leukotriene CysLT1-receptor antagonism on nasal adenosine monophosphate (AMP) challenge...Full Text Available

2004-06-01

425

Development of heavy-ion irradiation technique for single-event in semiconductor devices  

Energy Technology Data Exchange (ETDEWEB)

Heavy-ion irradiation technique has been developed for the evaluation of single-event effects on semiconductor devices. For the uniform irradiation of high energy heavy ions to device samples, we have designed and installed a magnetic beam-scanning system in a JAERI cyclotron beam course. It was found that scanned area was approximately 4 x 2 centimeters and that the deviation of ion fluence from the average value was less than 7%. (author)

1997-03-01

426

Characterization of the corrosion behavior of the carbon steel liner in Hanford Site single-shell tanks  

Energy Technology Data Exchange (ETDEWEB)

Six safety initiatives have been identified for accelerating the resolution of waste tank safety issues and closure of unreviewed safety questions. Safety Initiative 5 is to reduce safety and environmental risk from tank leaks. Item d of Safety Initiative 5 is to complete corrosion studies of single-shell tanks to determine failure mechanisms and corrosion control options to minimize further degradation by June 1994. This report has been prepared to fulfill Safety Initiative 5, Item d. The corrosion mechanisms that apply to Hanford Site single-shell tanks are stress corrosion cracking, pitting/crevice corrosion, uniform corrosion, hydrogen embrittlement, and microbiologically influenced corrosion. The corrosion data relevant to the single-shell tanks dates back three decades, when results were obtained from in-situ corrosion coupons in a few single-shell tanks. Since that time there have been intertank ...

1994-06-01

427

A single-stranded gap in human immunodeficiency virus unintegrated linear DNA defined by a central copy of the polypurine tract.  

UK PubMed Central (United Kingdom)

The structure of unintegrated human immunodeficiency virus type 1 (HIV-1) DNA from acutely infected human lymphoid cells was analyzed by nuclease S1 cleavage. We observed a unique, discrete single-stranded...Full Text Available

1991-05-01

428

Real World Evaluation of Dual-Zone ICD and CRT-D Programming Compared to Single-Zone Programming: The ALTITUDE REDUCES Study  

British Library Electronic Table of Contents (United Kingdom)

Tachycardia Detection, ICD, CRT-D Devices, Appropriate and Inappropriate Shock.-Introduction: We evaluated the frequency of appropriate and inappropriate shocks and survival in patients using dual-zone programming versus single-zone programming. Methods and Results: For the ALTITUDE REDUCES study, patients were followed for 1.6 1.1 years. The 12-month incidence of any shock was lower for dual-versus single-zone programmed detection at rates -170 bpm and between 170-200 bpm (P < 0.001). Appropriate shock rates at 1 year were also lower with dual-zone programming in these rate intervals (single zone 9.1%, 5.4%, P < 0.001, dual zone 6.7%, 4.7%, P < 0.02). There were no detectable differences between single- and dual-zone shock incidence at detection rates - 200 bpm (P = 0.14). Inappropriate s...

2011-01-01

429

Anisotropy in Magnetic Properties and Electronic Structure of Single Crystal LiFePO4  

Energy Technology Data Exchange (ETDEWEB)

We report the experimental and theoretical results on the anisotropies in the magnetic properties and x-ray absorption spectra of single-crystal LiFePO4. A mean-field theory is developed to explain the observed strong anisotropies in Lande g-factor, paramagnetic Curie temperature, and effective moment for LiFePO4 single crystals. The values of the in-plane nearest- and next-nearest-neighbor spin exchange (J1 and J2), interplane spin exchange (J{perpendicular}), and single-ion anisotropy (D), obtained recently from neutron scattering measurements, are used for calculating the Curie temperatures with the formulas derived from the mean-field Hamiltonian. It is found that the calculated Curie temperatures match well with that obtained by fitting the magnetic susceptibility curves to the modified Curie-Weiss law. For the polarized Fe K-edge x-ray absorption spectra of single-crystal LiFePO4, a different ...

2008-01-01

430

An evaluation of low-dose single-slice helical CT in pulmonary CT scan  

International Nuclear Information System (INIS)

Objective: To investigate the feasibility of low-dose single-slice helical CT in pulmonary CT scan and evaluate the clinical application. Methods: Thirteen cases were selected out of 132 cases, in which low-dose (50mAs) single-slice helical CT scan of chest was performed. This set of cases included 7 cases of multiple metastatic nodules; 3 of solitary pulmonary, nodule; and 3 of pulmonary patchy lesions. Regular dose (170mAs) CT scan was also performed on all those patients. The regular dose and low dose CT scan were compared on sensitivity of detecting the lesions; the performance in demonstrating the details of the abnormalities; and the capability of revealing the segmental bronchi as well. Results: The same number and size of the pulmonary nodules were revealed with scan modalities loaded with different doses. No significant difference in demonstrating the details of the nodules and the segmental bronchi was found between both modalities ...

2006-04-01

431

The peak to background method in quantitative ion microprobe analysis of thick biological specimens  

Energy Technology Data Exchange (ETDEWEB)

The use of the ratio of the characteristic intensity to the continuum background intensity (P/B ratio) of the X-ray spectrum for a quantitative ion microprobe (IMP) or PIXE (particle induced X-ray emission) analysis of thin biological specimens was proposed previously. The IMP analysis of thick biological specimens is also of considerable practical use. In this paper, the possibility of using the P/B ratio to quantify minor elements in thick biological specimens is investigated. The epoxy resin based standards with gradual concentrations of KCNS up to 0.6 mol/kg and NBS bovine liver were analyzed by a 27 MeV {alpha} particle microprobe. The measured peak to background ratios (between 4.4 to 5.7 keV) agreed well with the theoretical calculations. The calculations showed that the concentration dependence of the P/B ratios was determined mainly by the absorption of X-rays in specimens. The results indicate that the P/B method is useful for IMP analysis of thick ...

1991-05-01

432

The energy supply for the new housing area `De Groote Wielen`, Den Bosch, Netherlands; De energievoorziening voor de nieuwbouwlocatie De Groote Wielen  

Energy Technology Data Exchange (ETDEWEB)

`De Groote Wielen` is going to be a newly built area of the municipality Den Bosch, Netherlands. In the period 1998-2011 circa 6,200 houses and 39,000 m{sup 2} will be built. Under the authority of the municipality Den Bosch CE compared a few energy supply options. Attention is paid to three different forms of energy supply: traditional supply of natural gas and electricity, supply of heat (produced by cogeneration gas engines and collective electrical heat pumps) and electricity, and supply of electricity by means of individual heat pumps for each house. Two levels of the energy performance standard are taken into account: 1.2 and 1.0. Also costs and resulting emissions of those options are compared. Next to a quantitative discussion, also the qualitative consequences of the three concepts are dealt with. The most important quantitative consequence concerns the flexibility of the energy supply for the future, in particular in the view of a ...

1996-07-01

433

The behavior of waste rock piles; Le comportement des haldes de steriles  

Energy Technology Data Exchange (ETDEWEB)

Under the auspices of the Mine Environment Neutral Drainage (MEND) Program, several waste rock piles were monitored and characterized. Acid rock drainage (ARD) became a mechanism better understood based on the data acquired during these projects. Numerical simulation was used to better comprehend the quantitative issues associated with the characterization of three specific sites for the purpose of this study. The sites selected were the south waste rock pile of the Doyon Mine in Quebec, the Northdale of the mining district of Ronnenberg in Germany, and the waste rock pile of the Sugar Shack South of the Questa mine in New Mexico. The observed and simulated conditions were very distinct from one mine to another, even if the same mechanisms were involved. The dominant oxygen and heat transfer mechanisms displayed the most varied behavior between the sites. ARD control or site rehabilitation decisions were based on the quantitative understanding ...

2000-07-01

434

Technical note: A physical phantom for assessment of accuracy of deformable alignment algorithms  

International Nuclear Information System (INIS)

The purpose of this study was to investigate the feasibility of a simple deformable phantom as a QA tool for testing and validation of deformable image registration algorithms. A diagnostic thoracic imaging phantom with a deformable foam insert was used in this study. Small plastic markers were distributed through the foam to create a lattice with a measurable deformation as the ground truth data for all comparisons. The foam was compressed in the superior-inferior direction using a one-dimensional drive stage pushing a flat 'diaphragm' to create deformations similar to those from inhale and exhale states. Images were acquired at different compressions of the foam and the location of every marker was manually identified on each image volume to establish a known deformation field with a known accuracy. The markers were removed digitally from corresponding images prior to registration. Different image registration algorithms were tested using this method. Repeat measurement of marker ...

2007-07-01

435

Simultaneous assessment of left ventricular function from gated myocardial perfusion SPECT. Utility of QGS (Quantitative Gated SPECT) program  

International Nuclear Information System (INIS)

Quantitative gated SPECT (QGS) was evaluated in 7 normal volunteers and 31 patients with cardiac diseases. Adequate cut off value of a prefilter was 0.45. In phantom, the left ventricular volume value was 93.9% of determined value by 180-degree projection in L type and 98.8% by 360-degree projection in opposed type. In normal volunteers, LVEF measured by QGS program related to value by first pass method. As for functional map, regional EF and wall motion decreased at the septum side, and wall thickening at base side of heart. Good correlation was recognized (p<0.0001) between blood flow image and functional map (regional EF and wall thickening). In 20 cases of acute myocardial infarction, lesion was detected conspicuously in regional EF and wall motion. The accuracy of coronary arterial stenosis improved in functional map (regional EF 92%, wall motion 92% and wall thickening 88%). In particular, the accuracy of 3 rami lesion was 100% in functional map and higher ...

1998-08-01

436

SIMS and XRD measurements for the critical review of carbon diffusivity derivation from hardness profiles  

Energy Technology Data Exchange (ETDEWEB)

Microhardness decarburization profiles are often used in the industry to estimate the carbon distribution in steels. For quantitative evaluation, an analysis based on diffusion theory must be performed, the fundamentals and mathematical basics of which are presented. If the relationship between hardness and carbon content is known, microhardness-distance curves of steels can be analyzed in this way. For martensitic grades, for instance, a linearized expression holds in the concentration range from 0.15 to 0.6 m.% C. Microhardness depth profiles of higher carbon steels and other microstructures, however, are also evaluated in the literature. The applicability of quantitative diffusion modeling is discussed in detail. Through hardenable rolling bearing steel 100Cr6 (1.3505, SAE 52100) serves as model material: carbon concentration-distance curves are measured with high accuracy by secondary ion mass spectrometry (SIMS) and compared with ...

2007-07-01

437

Repeated quantitative bone scintigraphy in patients with prostatic carcinoma treated with orchiectomy  

Energy Technology Data Exchange (ETDEWEB)

Bone scintigraphy was performed in 16 men with newly diagnosed prostatic carcinoma before orchiectomy as well as 2 weeks and 2 months after operation. The uptake in the lower thoracic and lumbar vertebrae was registered up to 240 min after injection of /sup 99m/Tc-MDP and was then calculated for each patient and vertebra. The relative standard deviation in measured uptake due to measuring technique was estimated to be +-7%. In eight patients, who had normal bone scintigraphies before orchiectomy, there were no changes in the uptake values after operation. The remaining eight patients had widespread metastatic involvement prior to treatment, six of these patients showed a so-called 'flare phenomenon' in the abnormal vertebrae which means an initial increase in uptake after operation followed by a decreased uptake in response to therapy. One patient had a continuously increased uptake in all the abnormal vertebrae which correlated well with the clinical progression of ...

1988-07-01

438

Repeated quantitative bone scintigraphy in patients with prostatic carcinoma treated with orchiectomy  

International Nuclear Information System (INIS)

Bone scintigraphy was performed in 16 men with newly diagnosed prostatic carcinoma before orchiectomy as well as 2 weeks and 2 months after operation. The uptake in the lower thoracic and lumbar vertebrae was registered up to 240 min after injection of "9"9"mTc-MDP and was then calculated for each patient and vertebra. The relative standard deviation in measured uptake due to measuring technique was estimated to be #+-#7%. In eight patients, who had normal bone scintigraphies before orchiectomy, there were no changes in the uptake values after operation. The remaining eight patients had widespread metastatic involvement prior to treatment, six of these patients showed a so-called 'flare phenomenon' in the abnormal vertebrae which means an initial increase in uptake after operation followed by a decreased uptake in response to therapy. One patient had a continuously increased uptake in all the abnormal vertebrae which correlated well with the clinical progression of the disease, while ...

439

Quantitative monitoring of the fluorination process by neutron counting  

Energy Technology Data Exchange (ETDEWEB)

Plutonium metal is produced by reducing PuF{sub 4} prepared from PuO{sub 2} by fluorination. Both fluorination and reduction are batch processes at the Los Alamos Plutonium Facility. The conversion of plutonium oxide to fluoride greatly increases the neutron yield, a result of the high cross section for alpha-neutron ({alpha},n) reactions on fluorine targets compared to the (more than 100 times) smaller {alpha},n yield on oxygen targets. Because of the increase, total neutron counting can be used to monitor the conversion process. This monitoring ability can lead to an improved metal product, reduced scrap for recycle, waste reduction, minimized reagent usage, and reduce personnel radiation exposures. A new stirred-bed fluorination process has been developed simultaneously with a recent evaluation of an automated neutron-counting instrument for quantitative process monitoring. Neutrons are counted with polyethylene-moderated {sup 3}He-gas proportional counters. ...

1993-12-31

440

Quantitative evaluation of bile diversion surgery utilizing /sup 99m/Tc HIDA scintigraphy  

Energy Technology Data Exchange (ETDEWEB)

This is a report of 21 patients presenting with epigastric pain, bilious vomiting, upper gastrointestinal bleeding, iron-deficiency anemia, and weight loss, who had undergone Billroth II gastrectomy from 3 to 35 yr earlier. Eighteen of 21 patients were found to have significant enterogastric reflux indices varying from 60% to 95% demonstrated by /sup 99m/Tc HIDA scintigraphy. Thirteen patients had diversion antireflux surgery in the form of a Roux-en-Y procedure, and 1 patient had a Henley loop jejunal interposition. Postoperative /sup 99m/Tc HIDA scintigraphic studies showed the enterogastric reflux indices to have decreased significantly to a range of 2%-26% (p less than 0.00001). There was marked improvement of symptoms, including correction of anemia and weight gain in those patients who had been anemic or who had sustained earlier weight loss. The enterogastric reflux indices of 10 asymptomatic control patients after Billroth II gastrectomy ranged from 4% to 45%. /sup 99m/Tc HIDA ...

1983-02-01

441

Quantitative bone scintigraphy in prostatic carcinoma - long-term response to treatment  

Energy Technology Data Exchange (ETDEWEB)

Quantitative bone scintigraphy was performed in 24 patients with prostatic carcinoma before orchiectomy and up to one to four years after operation. The gamma camera count rate was recorded over the lower thoracic and all lumbar vertebrae 4 h after injection of [sup 99m]Tc-MDP. Twelve patients has normal bone scintigrams throughout the study. They showed from two years after operation a slight increase in count rate values compared with the preoperative values, probability due to hormonal changes after orchiectomy and to age-related alterations in skeletal metabolism. Twelve patients had abnormal bone scintigrams. They showed as a response to treatment the flare phenomenon with an increase in count rate over the abnormal vertebrae when measured two weeks after operation followed by a decrease after two months. The lowest count rate values were obtained between six months and one year after operation. Thereafter the count rate seemed to remain on the same level. An ...

1993-10-01

442

Quantitative bone scintigraphy in prostatic carcinoma - long-term response to treatment  

International Nuclear Information System (INIS)

Quantitative bone scintigraphy was performed in 24 patients with prostatic carcinoma before orchiectomy and up to one to four years after operation. The gamma camera count rate was recorded over the lower thoracic and all lumbar vertebrae 4 h after injection of "9"9"mTc-MDP. Twelve patients has normal bone scintigrams throughout the study. They showed from two years after operation a slight increase in count rate values compared with the preoperative values, probability due to hormonal changes after orchiectomy and to age-related alterations in skeletal metabolism. Twelve patients had abnormal bone scintigrams. They showed as a response to treatment the flare phenomenon with an increase in count rate over the abnormal vertebrae when measured two weeks after operation followed by a decrease after two months. The lowest count rate values were obtained between six months and one year after operation. Thereafter the count rate seemed to remain on the same level. An ...

443

Quantitative assessment of mineral content in metacarpal bone with Fuji computed radiography  

Energy Technology Data Exchange (ETDEWEB)

A new microdensitometry method for quantitative assessment of bone mineral content using Fuji computed radiography (FCR) was developed and the results were compared with those obtained by the conventional film-screen method. Using both methods, X-ray pictures of the 2nd metacarpal bone were taken with a reference aluminum step wedge in nine normal subjects and nine parameters representing the width and density of bone marrow and cortex were calculated in middle of the bone shaft. Interobserver reproducibility assessed for three parameters was significantly higher in the FCR method than the conventional one. The value of {Sigma}GS computed by the FCR method, that is equivalent to the net bone density of the transverse section of the shaft, showed higher correlation with the one obtained by computed tomography in comparison with the conventional method. In our FCR method, moreover, interobserver reproducibility and accuracy was improved by employing automatic ...

1990-05-01

444

Quantitative assessment of mineral content in metacarpal bone with Fuji computed radiography  

International Nuclear Information System (INIS)

A new microdensitometry method for quantitative assessment of bone mineral content using Fuji computed radiography (FCR) was developed and the results were compared with those obtained by the conventional film-screen method. Using both methods, X-ray pictures of the 2nd metacarpal bone were taken with a reference aluminum step wedge in nine normal subjects and nine parameters representing the width and density of bone marrow and cortex were calculated in middle of the bone shaft. Interobserver reproducibility assessed for three parameters was significantly higher in the FCR method than the conventional one. The value of #SIGMA#GS computed by the FCR method, that is equivalent to the net bone density of the transverse section of the shaft, showed higher correlation with the one obtained by computed tomography in comparison with the conventional method. In our FCR method, moreover, interobserver reproducibility and accuracy was improved by employing automatic ...

1990-01-01

445

Quantitative assessment of cancer risk from exposure to diesel engine emissions  

Energy Technology Data Exchange (ETDEWEB)

Quantitative estimates of lung cancer risk from exposure to diesel engine emissions were developed using data from three chronic bioassays with Fischer 344 rats. Human target organ dose was estimated with the aid of a comprehensive dosimetry model. This model accounted for rat-human differences in deposition efficiency, normal particle clearance rates, transport of particles to lung-associated lymph nodes, respiration rates, and lung surface area, as well as high-dose inhibition of particle clearance. Recent evidence indicates that the inert carbon core of the diesel particulate matter is likely to be the primary source of carcinogenicity. The epithelial tissue lining the alveoli and lower airways is the primary target site for induction of lung tumors. Dose was therefore based upon the concentration of carbon particulate matter per unit lung surface area. Unit risk estimates were developed using either a time-to-tumor or a linearized multistage model. The unit ...

1993-02-01

446

Quantitative assessment of bone scintigraphy in the hip joint disease  

International Nuclear Information System (INIS)

Quantitative assessment of bone scintigraphy was performed in fifty-six patients with hip joint disease including femoral neck fracture, aseptic necrosis of the femoral head, traumatic dislocation of the hip, Perthes disease, and transient synovitis of the hip. In the static study, bone scintigraphy was obtained 3 hours after injection of sup(99m)Tc-MDP by gamma camera equipped with a computer and uptake ratios were calculated. In the dynamic study, bone scintigraphy was performed in one, 3 and 5 hours after injection of radionuclide. Femoral head uptake ratio was markedly decreased in osteonecrosis following femoral neck fracture and characteristically increased in aseptic necrosis of the femoral head but prolonged retention of sup(99m)Tc-MDP could be observed. Uptake ratios of epiphysis were decreased in Perthes disease but normal in transient synovitis of the hip. Static and dynamic study of bone scintigraphy may be useful for early diagnosis and treatment in ...

447

Quantitation of acyl migration during lipase-catalyzed acidolysis, and of the regioisomers of structured triacylglycerols formed  

DEFF Research Database (Denmark)

Various MLM-type (M, medium-chain fatty acids; L, long-chain fatty acids) structured triacylglycerols were produced in pilot- or small-scale packed-bed reactors by lipase-catalyzed acidolysis. The incorporation and acyl migration of octanoic acid were measured by gas chromatography and Grignard degradation, and ranged from 39.0 to 48.7% and 0.6 to 9.3%, respectively. Quantitation of triacylglycerol molecular species was performed by ammonia negative ion chemical ionization (NICI) mass spectrometry (MS). The proportion of ACN (acyl carbon number) 34 species that contained one C-18 fatty acid and two C-8:0, in samples analyzed, varied from 12.5 to 23.2%. The selected regioisomers MLM and MML within the ACN 34 species group were quantified by NICI tandem MS (MS/MS) and were in the range of 97.1 to 98.4% and 1.6 to 2.9%, respectively. There was no correlation between the level of acyl migration during lipase-catalyzed esterification and the level of regioisomers of the ...

2001-01-01

448

Post-column reaction detector for platinum(II) antieoplastic agents  

Energy Technology Data Exchange (ETDEWEB)

The development and evaluation of a post-column reaction detector sensitive to platinum(II) complexes is presented in which sodium bisulfite is used as the derivatizing agent with potassium dichromate as an activating agent. The influences of mobile phase changes (i.e., pH, organic modifiers, electrolytes), oxygen, metal ions, and order of reagent addition on reaction kinetics and product yield are defined and used in optimization of detector response. Detection at lambda/sub max/ 290 nm results in an on-line post-column sensitivity of 40-60 ng/mL for selected cis-dichloroplatinum complexes and a sensitivity of 300-1200 ng/mL for four (substituted)-malonato-platinum complexes. The reaction detector is used to monitor the kinetics of aquation of cisplatin (CDDP) and to quantitate CDDP degradation in plasma. As the sensitivity for CDDP in plasma is comparable to that achieved from high pressure liquid chromatography (HPLC) effluent fractionation/off-line flameless ...

1984-03-01

449

Microstructural Coarsening during Thermomechanical Fatigue and Annealing of Micro Flip-Chip Solder Joints  

Energy Technology Data Exchange (ETDEWEB)

Microstructural evolution due to thermal effects was studied in micro solder joints (55 {+-} 5 {micro}m). The composition of the Sn/Pb solder studied was found to be hypereutectic with a tin content of 65--70 wt%.This was determined by Energy Dispersive X-ray analysis and confirmed with quantitative stereology. The quantitative stereological value of the surface-to-volume ratio was used to characterize and compare the coarsening during thermal cycling from 0--160 C to the coarsening during annealing at 160 C. The initial coarsening of the annealed samples was more rapid than the cycled samples, but tapered off as time to the one-half as expected. Because the substrates to which the solder was bonded have different thermal expansion coefficients, the cycled samples experienced a mechanical strain with thermal cycling. The low-strain cycled samples had a 2.8% strain imposed on the solder and failed by 1,000 cycles, despite undergoing less ...

1998-12-01

450

Mapping quantitative trait loci controlling milk production in dairy cattle by exploiting progeny testing  

Energy Technology Data Exchange (ETDEWEB)

We have exploited {open_quotes}progeny testing{close_quotes} to map quantitative trait loci (QTL) underlying the genetic variation of milk production in a selected dairy cattle population. A total of 1,518 sires, with progeny tests based on the milking performances of >150,000 daughters jointly, was genotyped for 159 autosomal microsatellites bracketing 1645 centimorgan or approximately two thirds of the bovine genome. Using a maximum likelihood multilocus linkage analysis accounting for variance heterogeneity of the phenotypes, we identified five chromosomes giving very strong evidence (LOD score {ge} 3) for the presence of a QTL controlling milk production: chromosomes 1, 6, 9, 10 and 20. These findings demonstrate that loci with considerable effects on milk production are still segregating in highly selected populations and pave the way toward marker-assisted selection in dairy cattle breeding. 44 refs., 4 figs., 3 tabs.

1995-02-01

451

Mapping of quantitative trait loci (QTL) for production, resistance and tolerance traits in Salix. Final Report  

Energy Technology Data Exchange (ETDEWEB)

Quantitative trait loci (QTL) for growth traits, water use efficiency and tolerance/resistance against metals and herbivores have been identified. A hybrid F2 population originating from a cross between a Salix dasyclados-clone (SW901290) and a S. viminalis-clone ('Jorunn') was used for the different studies in this project. The growth response was analyzed in a greenhouse experiment with two water treatments, normal and drought. In addition, three field experiments with contrasting soils and climates were established. QTL specific for each treatment or field environment but also QTL stable over the treatments or field environments were detected. Each QTL explained from 8 to 29 % of the phenotypic variation depending on trait, treatment or field environment. Clusters of QTL for different traits were mapped indicating a common genetic base or tightly-linked QTL. Stable QTL identified for dryweight can be useful tools for early selection in Salix. ...

2004-05-01

452

How to overestimate risks of ionizing radiations  

International Nuclear Information System (INIS)

Ignoring the numerous, known and mainly unknown, interactions between chemicals and ionizing radiations, causes strong controversy about the risks of ionizing radiations. Yet the best known interactions between chemicals and radiations is that between radon and tobacco smoke. Although it is and it will be always impossible to derive quite quantitative laws for this interaction, it has been possible to derive some semi-quantitative relationships based on reasonable assumptions and statistics on lung cancer deaths in developed countries. They show that ignoring the dangers of tobacco smoking as we did still long after we had recognised the dangers of radiations, could asses to radiations thirty or forty times more risks than reality. As present world is flown by tens of thousands chemicals, little or not present in a natural environment, and as it would be very surprising that some hundreds of these do not behave like those contained in tobacco ...

453

How citation boosts promote scientific paradigm shifts and Nobel Prizes  

CERN Document Server

Nobel Prizes are commonly seen to be among the most prestigious achievements of our times. Based on mining several million citations, we quantitatively analyze the processes driving paradigm shifts in science. We find that groundbreaking discoveries of Nobel Prize Laureates and other famous scientists are not only acknowledged by many citations of their landmark papers. Surprisingly, they also boost the citation rates of their previous publications. Given that innovations must outcompete the rich-gets-richer effect for scientific citations, it turns out that they can make their way only through citation cascades. A quantitative analysis reveals how and why they happen. Science appears to behave like a self-organized critical system, in which citation cascades of all sizes occur, from continuous scientific progress all the way up to scientific revolutions, which change the way we see our world. Measuring the "boosting effect" of landmark papers, ...

2011-01-01

454

Dynamic quantitative bone scintigraphy in patients with prostatic carcinoma treated by orchiectomy  

International Nuclear Information System (INIS)

Dynamic quantitative bone scintigraphy was performed on 31 men with prostatic carcinoma before orchiectomy as well as 2 weeks, 2 and 6 months postoperatively. After injection of technetium methylene diphosphonate Tc 99m ("9"9"mTc-MDP) the count rate was recorded as serial images over the lower thoracic and all the lumbar vertebrae from 1 to 240 min post-injection. Thirteen men had normal bone scintigrams with no changes in "9"9"mTc-MDP content at the four different investigation times. Eighteen men had skeletal metastases. Throughout the study half of the abnormal vertebrae in these patients showed an abnormal count rate after only 6 min post-injection. After 1 h it was possible in almost all abnormal vertebrae to predict abnormal bone uptake. In response to therapy a 'flare phenomenon' with an increase in count rate was seen 2 weeks after orchiectomy followed by a decrease 2 months postoperatively in most of the abnormal vertebrae. The count rate decreased even ...

455

Diagnosis of breast cancer with MR imaging using the magnetization transfer contrast and a newly-developed breast surface coil for the supine position  

Energy Technology Data Exchange (ETDEWEB)

We developed a new breast surface coil for the supine position. The subjects consisted of 9 patients with breast cancer varying from 46 to 60 years of age (average: 52). The cancer image of the SPGR (CE+) method was compared with that of the FSMTC (MTC-SPGR (CE+)) method and that of the FSMTC (MTC-SPGR with fat-saturation (CE+)) method in the sagittal section after injection of Gd-DTPA (0.1 mmol/kg). Quantitative analyses were performed before and after injection of Gd-DTPA in 6 patients. Three patients were excluded from the quantitative analyses owing to the clear detection of tumors in the fat tissue. Signal intensity measurements were systematically performed in each region of interest (ROI), i.e. the cancer lesion, the surrounding mammary gland. Statistical analyses showed significant differences between the lesions using the FSMTC (MTC-SPGR (CE+)), and the FSMTC (MTC-SPGR with fat-saturation (CE+)) methods and the lesions using the SPGR ...

1998-09-01

456

Determination of microsomal lauric acid hydroxylase activity by HPLC with flow-through radiochemical quantitation  

International Nuclear Information System (INIS)

An assay for the microsomal hydroxylation of lauric acid (LA), based on HPLC with flow-through radiochemical detection, has been developed. Conditions were optimized for resolution and quantitation of three microsomal metabolites of "1"4C-LA, one of which has not been reported previously as a metabolite of LA in mammalian microsomal incubations. These products, 12-(omega)-hydroxy-LA, 11-(omega-1)-hydroxy-LA, and a novel metabolite, 10-(omega-2)-hydroxy-LA, were isolated by HPLC and identified by gas chromatography/mass spectrometry. In the presence of NADPH, the formation of all three metabolites was linear with time and microsomal protein concentration. Hydrogen peroxide also supported the microsomal metabolism of LA, although the ratio of metabolites was substantially different than that produced by NADPH-supported microsomes. Several biochemical probes (metyrapone, #alpha#-naphthoflavone, 2-diethylaminoethyl-2,2-diphenylvalerate hydrochloride, and 10-undecynoic ...

457

Depth profile analysis on the nanometer scale by a combination of electron probe microanalysis (EPMA) and focused ion beam specimen preparation (FIB)  

International Nuclear Information System (INIS)

Electron probe microanalysis (EPMA) offers high sensitivity and high accuracy in quantitative measurements of chemical compositions and mass coverages. Owing to the low detection limits of the wavelength-dispersive technique, monolayers with mass coverages of about 0.05 pg cm z can be detected. Assuming a density of 5 g cm--3 this corresponds to a thickness of 0.1 nm. With these advantages in mind, EPMA was extended to depth profile analysis in the sub-micron range using a surface removal technique. The present paper shows how depth profile analysis can be improved by combining EPMA and the focused ion beam (FIB) technique. The focused ion beam system uses a Ga+ ion beam. The ion beam allows the milling of defined geometries on the nanometer scale, so that very shallow bevels with exactly defined angles in relation to the surface can be obtained. Low surface damage is expected due to low sputtering effects. Calibrated WDX measurements along the bevel deliver ...

458

Comparison between NIR, MIR, concatenated NIR and MIR analysis and hierarchical PLS model. Application to virgin olive oil analysis.  

Science.gov (United States)

This work investigates the potential use of simultaneously near-infrared (NIR) and mid-infrared (MIR) spectroscopies for the quantitative analysis of fatty acids and triacylglycerols and for identifying the Registered Designation of Origin (RDO) of extra virgin olive oils. The two spectral ranges were used separately using PLS and PLS-DA regressions. To combine both information, concatenated matrix was used at the first time, multiblock method using H-PLS models were constructed at the second time. The models were compared in terms of prediction errors. The results obtained with MIR spectroscopy are better than the ones obtained with NIR spectroscopy. The H-PLS methodology seems to be very interesting for quantitative analysis with the use of additional information in the NIR range, which is not present in the MIR one. For RDO identification by discriminant analysis, the use of multiblock method was less efficient. PMID:20433960

2010-03-29

459

Climate Change, a Case Study of Media Construction of Environmental Problems; El Cambio Climatico como Casuistica de la Construccion Mediatica de los Problemas Medioambientales  

Energy Technology Data Exchange (ETDEWEB)

Nowadays climate change is one of the environmental problems in the global policy agenda. However, in countries like United States and United Kingdom the media started to report regularly on this issue in 1988. Since then many researches have been carrying out focused on how the media influence, along with other factors, public understanding of climate change through the media construction of the problem in several countries. Given the implications of social acceptance for design and implementation of public policies on mitigation and adaptation to climate change, the overall aim of this report is to review the status of the issue from a qualitative and quantitative approach. Qualitatively, media construction of climate change is described as the result of different processes taking place at macro and micro scales. Interactions among scientists, politicians, industry, the media themselves and the social context are considered macro-scale influences, while ...

2009-07-21

460

Calibration-Free Laser-Induced Breakdown Spectroscopy: State of the art  

Energy Technology Data Exchange (ETDEWEB)

The aim of this paper is offering a critical review of Calibration-Free Laser-Induced Breakdown Spectroscopy (CF-LIBS), the approach of multi-elemental quantitative analysis of LIBS spectra, based on the measurement of line intensities and plasma properties (plasma electron density and temperature) and on the assumption of a Boltzmann population of excited levels, which does not require the use of calibration curves or matrix-matched standards. The first part of this review focuses on the applications of the CF-LIBS method. Quantitative results reported in the literature, obtained in the analysis of various materials and in a wide range of experimental conditions, are summarized, with a special emphasis on the departure from nominal composition values. The second part is a discussion of the simplifying assumptions which lie at the basis of the CF-LIBS algorithm (stoichiometric ablation and complete atomization, thermal equilibrium, homogeneous ...

2010-01-15

461

Calibration-Free Laser-Induced Breakdown Spectroscopy: State of the art  

International Nuclear Information System (INIS)

The aim of this paper is offering a critical review of Calibration-Free Laser-Induced Breakdown Spectroscopy (CF-LIBS), the approach of multi-elemental quantitative analysis of LIBS spectra, based on the measurement of line intensities and plasma properties (plasma electron density and temperature) and on the assumption of a Boltzmann population of excited levels, which does not require the use of calibration curves or matrix-matched standards. The first part of this review focuses on the applications of the CF-LIBS method. Quantitative results reported in the literature, obtained in the analysis of various materials and in a wide range of experimental conditions, are summarized, with a special emphasis on the departure from nominal composition values. The second part is a discussion of the simplifying assumptions which lie at the basis of the CF-LIBS algorithm (stoichiometric ablation and complete atomization, thermal equilibrium, homogeneous ...

2010-01-01

462

Brain development during the first year of life. Quantitative assessment with ADC imaging  

International Nuclear Information System (INIS)

Brain development during the first year of life was assessed quantitatively using apparent diffusion coefficient (ADC) images constructed from diffusion-weighted MR image data. The imaging plane was coronal at the section of the pons. The cerebral peduncle, internal capsule, corona radiata, superior longitudinal fasciculus and thalamus were selected for evaluation of their ADC values. A diffusion sensitive gradient was added in the anteroposterior direction. Thus the orientation of nerve fibers in the cerebral peduncle, internal capsule and corona radiata was perpendicular to it, and that in the superior longitudinal fasciculus was parallel to it. In neonates, the cerebral peduncle and internal capsule, having been moderately myelinated at birth, showed the slowest diffusion. The corona radiata and superior longitudinal fasciculus, having been unmyelinated at birth, showed the fastest diffusion. The thalamus had intermediate diffusion. These neonatal diffusions ...

463

Bone scintigraphy in fluoride treated osteoporosis  

Energy Technology Data Exchange (ETDEWEB)

Quantitative bone scintigraphy was performed on 23 white females with post-menopausal osteoporosis and vertebral compression fractures. These patients were then entered into a randomized, double-blind clinical trial or sodium fluoride therapy (NaF=14, placebo=9) which included repeat bone scintigraphy every six months. Scintigraphic images were acquired for 500K counts per image over the total body with computer acquisition over the posterior thoracic and lumbar spine. Images were obtained on a wide field-of-view gamma camera two hours after injecting 15 mCi of Tc-99m MDP. Data analysis showed a significant reduction in the activity ratio of abnormal vertebral body to normal vertebral body in those patients treated with sodium fluoride (paired t-test p=0.0095). No significant change was observed in the control group of (p=0.142). These results suggest that sodium fluoride therapy promotes more rapid healing of osteoporotic vertebral fractures. They also demonstrate ...

1985-05-01

464

Atomistic Simulation of Water Percolation and Proton Hopping in Nafion Fuel Cell Membrane  

Energy Technology Data Exchange (ETDEWEB)

We have performed a detailed analysis of water clustering and percolation in hydrated Nafion configurations generated by classical molecular dynamics simulations. Our results show that at low hydration levels H2O molecules are isolated and a continuous hydrogen-bonded network forms as the hydration level is increased. Our quantitative analysis has established a hydration level (?) between 5 and 6 H2O/SO3- as the percolation threshold of Nafion. We have also examined the effect of such a network on proton transport by studying the structural diffusion of protons using the quantum hopping molecular dynamics method. The mean residence time of the proton on a water molecule decreases by two orders of magnitude when the ? value is increased from 5 to 15. The proton diffusion coefficient in Nafion at a ? value of 15 is about 1.1x10-5 cm2/s in agreement with experiment. The results provide quantitative atomic-level evidence of water network ...

2010-11-04

465

Assessment of the effects of pixel loss on image quality in direct digital radiography  

Energy Technology Data Exchange (ETDEWEB)

Modern digital radiographic 'flat panel' detectors can exhibit a progressive form of image degradation arising from non-functioning pixels. The effect of these 'dead pixels' on the quantitative image quality measures of modulation transfer function (MTF), noise power spectrum (NPS) and detective quantum efficiency (DQE) is investigated by a simulated degradation of images obtained from an Hologic EPEX system. The effects on the semi-quantitive measures obtained from contrast threshold test objects and resolution gratings are also investigated. Results suggest that the contrast-detail tests often employed in quality assurance measures are not sufficient to reveal the presence of dead pixels until well beyond the recommended replacement point for the flat panel detector. However, measurements of spatial resolution using a line pairs phantom were found to be more sensitive to pixel loss. Measurement of the MTF, ...

2004-03-21

466

Assessment of the effects of pixel loss on image quality in direct digital radiography  

International Nuclear Information System (INIS)

Modern digital radiographic 'flat panel' detectors can exhibit a progressive form of image degradation arising from non-functioning pixels. The effect of these 'dead pixels' on the quantitative image quality measures of modulation transfer function (MTF), noise power spectrum (NPS) and detective quantum efficiency (DQE) is investigated by a simulated degradation of images obtained from an Hologic EPEX system. The effects on the semi-quantitive measures obtained from contrast threshold test objects and resolution gratings are also investigated. Results suggest that the contrast-detail tests often employed in quality assurance measures are not sufficient to reveal the presence of dead pixels until well beyond the recommended replacement point for the flat panel detector. However, measurements of spatial resolution using a line pairs phantom were found to be more sensitive to pixel loss. Measurement of the MTF, NPS and DQE can reveal small changes ...

2004-03-21

467

Application of quantitative sedimentology in the characterization of subsurface reservoirs and outcrop analogs  

Energy Technology Data Exchange (ETDEWEB)

The thesis deals with methods of describing the reservoir rock in central oil and gas fields on the Norwegian continental shelf. Methods of enhancing the level of recovery are dealt with. Following topics are given: Sand body dimensions and infill sequences of stable, humid-climate delta plain channels; minipermeameter-based study of permeability trends in channel sand bodies; significance of tidal cyclicity for modelling of reservoir heterogeneities in the lower Jurassic Tilje Formation, mid-Norwegian shelf; geometry and facies of large-scale flow units in fluvial-dominated fan-delta-front sequences; quantified fluvial architecture in ephemeral stream deposits of the Esplugafreda Formation (Palaeocene), Tremp-Graus Basin, northern Spain; the Safari project - collection and storage of field analogue data for quantitative reservoir modelling; sedimentary architecture of field analogues for reservoir information (SAFARI): a case study of the fluvial Escanilla ...

1994-12-31

468

An immunochemical approach to the study of DNA damage and repair. Technical progress report, May 1, 1989--April 30, 1992  

Energy Technology Data Exchange (ETDEWEB)

The overall objective of this project has been to develop immunochemical methods to quantitate unique DNA base damages in order to facilitate studies on radiation-induced damage production and repair. Specifically, we have been using antibodies raised to damaged bases to quantitate unique lesions in model systems in order to evaluate their potential biological consequences. Our approach has been to synthesize modified nucleotides or nucleosides, conjugate them to protein carriers, and use the conjugates as immunogens in rabbits or to prepare monoclonal antibodies. We have been studying damages that are stable radiolysis products found in X-irradiated DNA and thus of potential biological consequence. Our aim is to build an in vitro and in vivo data base on the interactions between model DNA lesions and such cellular enzymes as DNA polymerases and repair endonucleases. Initial studies have focused on pyrimidine ring saturation products (thymine ...

1992-05-01

469

An immunochemical approach to the study of DNA damage and repair  

Energy Technology Data Exchange (ETDEWEB)

The overall objective of this project has been to develop immunochemical methods to quantitate unique DNA base damages in order to facilitate studies on radiation-induced damage production and repair. Specifically, we have been using antibodies raised to damaged bases to quantitate unique lesions in model systems in order to evaluate their potential biological consequences. Our approach has been to synthesize modified nucleotides or nucleosides, conjugate them to protein carriers, and use the conjugates as immunogens in rabbits or to prepare monoclonal antibodies. We have been studying damages that are stable radiolysis products found in X-irradiated DNA and thus of potential biological consequence. Our aim is to build an in vitro and in vivo data base on the interactions between model DNA lesions and such cellular enzymes as DNA polymerases and repair endonucleases. Initial studies have focused on pyrimidine ring saturation products (thymine ...

1992-05-01

470

Additional information from quantitative 24-hour sup 99m Tc-MDP bone scintigraphy in patients with prostatic carcinoma  

Energy Technology Data Exchange (ETDEWEB)

Quantitative bone scintigraphy was performed at 4 and 24 h after injection of {sup 99m}Tc-MDP. The lower thoracic and all the lumbar vertebrae were recorded in 37 patients with prostatic carcinoma before orchiectomy as well as two weeks, two and six months postoperatively. Fourteen patients had normal bone scintigrams. By means of the measured variation in the count rate between normal vertebrae, the criterion for a vertebra to be considered as abnormal was determined using the 4 h-uptake values. For patients with normal scintigrams the count rate at 24 h was below the 4 h level and the mean 24 h/4 h ratio was determined to be 0.85 {+-} 0.09 (1 SD). Normal vertebrae in patients with skeletal metastases had only slightly lower count rate values at 24 h than at 4 h. Abnormal vertebrae showed a higher count rate at 24 h, especially two weeks postoperatively, while a tendency towards lower values than at 4 h was seen after 6 months. If the 24 h/4 h ratio is used as an ...

1991-01-01

471

Additional information from quantitative 24-hour "9"9"mTc-MDP bone scintigraphy in patients with prostatic carcinoma  

International Nuclear Information System (INIS)

Quantitative bone scintigraphy was performed at 4 and 24 h after injection of "9"9"mTc-MDP. The lower thoracic and all the lumbar vertebrae were recorded in 37 patients with prostatic carcinoma before orchiectomy as well as two weeks, two and six months postoperatively. Fourteen patients had normal bone scintigrams. By means of the measured variation in the count rate between normal vertebrae, the criterion for a vertebra to be considered as abnormal was determined using the 4 h-uptake values. For patients with normal scintigrams the count rate at 24 h was below the 4 h level and the mean 24 h/4 h ratio was determined to be 0.85 #+-# 0.09 (1 SD). Normal vertebrae in patients with skeletal metastases had only slightly lower count rate values at 24 h than at 4 h. Abnormal vertebrae showed a higher count rate at 24 h, especially two weeks postoperatively, while a tendency towards lower values than at 4 h was seen after 6 months. If the 24 h/4 h ratio is used as an ...

472

A quantitative structural analysis of the low temperature phase of lithium-7  

International Nuclear Information System (INIS)

Calculations in "7Li have been carried out for the differential coherent elastic scattering cross-section of thermal neutrons at a fixed scattering angle #theta#_0(148"o) and varying the energy of incident neutrons (or corresponding d-spacings). The results are reported, as variations of the ratio #SIGMA#_0"c"o"h (#theta#_0, d)/#SIGMA#_0"c"o"h (#theta#_0) with d-spacing, at atmospheric pressure and at two temperatures, 80 and 20 K. The calculations at 80 K correspond to BCC lithium whereas at 20 K all the possible crystallographic structures of polytype lithium (BCC, 9R, HCP and FCC) were considered. On comparing our results with the time-of-flight (TOF) measurements of Berliner et al. (Physical Review, B40, 12086, 1989) we find that up to 80 K lithium-7 does not undergo any martenistic transformation whereas the structural state at 20 K can be described by the co-existence of the original BCC phase with 9R, HCP and FCC closed packed structures. A quantitative ...

473

A multi-marker model for detecting chromosomal segments displaying QTL activity  

Science.gov (United States)

A statistical method is presented for detecting quantitative trait loci (QTLs), based on the linear model. Unlike methods able to detect a few well separated QTLs and to estimate their effects and positions, this method considers the genome as a whole and enables the detection of chromosomal segments involved in the differences between two homozygous lines, and their backcross, doubled haploid, or F[sub 2] progenies, for a quantitative trait. Genetic markers must be codominant, but missing markers are accepted, provided they are missing independently from the experiment. Asymptotic properties, which are of practical use, are developed. This method does not rely on strong genetic hypotheses, and thus does not permit any precise genetic analysis of the trait under study, but it does assess which regions of the genome are involved, whatever the complexity of the genetic determinism (number, effects and interactions among QTLs). Simultaneous use of ...

1993-08-01

474

Biosorption of lead, copper, and cadmium with continuous hollow-fiber microfiltration processes  

Energy Technology Data Exchange (ETDEWEB)

A hollow-fiber crossflow microfiltration membrane was utilized to retain a biomass of Pseudomonas aeruginosa PU21 for continuous biosorption of lead (Pb), copper (Cu), and cadmium (Cd) ions in single or ternary metal systems. The results obtained from the microfiltration systems showed that in both single and ternary biosorption, the metal removal efficiency based on a molar basis was clearly Pb > Cu > Cd. For a single-membrane process with an influent metal concentration of 200 {micro}M and a flow rate of 350 mL/h, the effluent concentration of Pb and Cu satisfied the national regulations for an influent volume of 6.3 L. With a three-metal influent, the adsorption capacity of the biomass for Pb, Cu, and Cd was reduced 4, 50, and 74% compared to that for single-metal adsorption. Selective biosorption with a three-column sequential microfiltration operation exhibited an enhancement of 40 and 57% of ...

1999-06-01

475

[Method of determining tissue renin activity using heterologous serum].  

Science.gov (United States)

The authors described a method for determination of tissue renin activity with heterologous substrate. The preparation of the substrate was performed at several stages: salting with amonium sulfate; dialisis of the precipitate till complete separation of amonium sulfate molecules; distruction of angiotensinases by interchangeble souring and alcalization of the medium; lyophylization of the pure substrate. The obtained renin-substrate was preserved in ampules and its usage had a series of advantages--duration, economic, a possibility for standartization of the determination, etc., which were described in details in the article. The described in details also the quantitative determination of the renin activity in the tissues (renal and cerebral) with the help of the obtained substrate as the moments, modiied by the authors, were indicated. PMID:436712

1979-01-01

476

The use of a mesoscale numerical model for evaluations of pollutant transport and diffusion in coastal regions and over irregular terrain  

Energy Technology Data Exchange (ETDEWEB)

A modelling approach is presented that appears to have the potential to provide reliable assessments of pollution concentration in coastal zones and complex terrain, where the assumptions behind current operational air quality models often are inadequate. With the use of a numerical mesoscale model (NMM), physically consistent flow fields can be predicted, thereby providing higher spatial and temporal resolution in the meteorological fields than would be available from a limited number of observation points. These predictions are used to calculate mean trajectories of pollutant parcels, as well as to provide quantitative estimates of pollution concentration using two techniques.

1983-03-01

477

The impacts of climate change on the Finnish economy  

Energy Technology Data Exchange (ETDEWEB)

The purpose of the project was to evaluate the potential influence of global warming on the Finnish economy and well-being during the next 50 to 100 years. In order to achieve this goal a cost-benefit analysis was conducted which produced a quantitative estimate of the economic and partially non-economic effects of the climate change projected to happen in Finland. The analysis utilised the natural scientific evidence produced by other SILMU projects in partial sector models. Also a broader view of the phenomena and the possibilities for restricting greenhouse gas emissions was briefly discussed and surveyed. Two of the more important side-goals were to develop the methodology for country analysis and study the possibilities for adaptation

1996-12-31

478

Tetra Pak : packaging systems and the environment; Tetra Pak : verpakking en milieu  

Energy Technology Data Exchange (ETDEWEB)

First, the problem of food packaging waste is introduced and one of the solutions, the Tetra Pak, is completely described. The article highlights the political sensitivity concerning the landfilling of packaging waste, as is done with the efforts of the Tetra Pak producer concerning the collection of used Tetra Paks and the results of these efforts. The document also informs us about the different recycling options for Tetra Paks, the qualitative prevention (using cleaner packaging), the quantitative prevention (using less packaging) and the sustainable development (using loner lasting packaging). The proposed four-step plan for a communication strategy is company-specific.

1997-05-01

479

Simple method for the high-temperature isolation of /sup 111/In from silver  

Energy Technology Data Exchange (ETDEWEB)

A method is proposed for the quantitative high-temperature isolation of /sup 111/In from silver irradiated by ..cap alpha..-particles into a gas phase containing a mixture of HCl and H/sub 2/O with a total pressure of about 3 Pa for these gases. It is shown that the indium evolved into the gas phase probably occurs in the form of at least three compounds, viz.., the trichloride, monochloride, and oxychloride, which have adsorption temperatures on quartz of around 385, 475, and 655 K, respectively. All these compounds are readily washed from the surface of quartz apparatus by a weak (0.05 M) solution of hydrochloric acid.

1987-07-01

480

Simple method for high-temperature separation of thallium isotopes from a bulk lead target  

Energy Technology Data Exchange (ETDEWEB)

A method is proposed for the quantitative isolation of radiothallium in gas form from proton-bombarded lead of mass up to 20 g. The molten lead is kept at about 800 K in hydrofluoric-acid vapor (HF/H/sub 2/O approx. = 1) at a reduced pressure (less than or equal to4 Pa). We used 99.9% lead with the U-240 cyclotron at the Nuclear Research Institute, Academy of Sciences of the Ukrainian SSR, or the phasotron at the Join Nuclear Research Institute, which gave protons at 65 and 680 MeV correspondingly.

1988-03-01

481

Simple method for high-temperature separation of thallium isotopes from a bulk lead target  

International Nuclear Information System (INIS)

A method is proposed for the quantitative isolation of radiothallium in gas form from proton-bombarded lead of mass up to 20 g. The molten lead is kept at about 800 K in hydrofluoric-acid vapor (HF/H_2O #approx =# 1) at a reduced pressure (#<=#4 Pa). We used 99.9% lead with the U-240 cyclotron at the Nuclear Research Institute, Academy of Sciences of the Ukrainian SSR, or the phasotron at the Join Nuclear Research Institute, which gave protons at 65 and 680 MeV correspondingly.

482

Shell effects in the symmetric-modal fission of pre-actinide nuclei  

International Nuclear Information System (INIS)

Mass distributions of fragments in the low-energy fission of nuclei from "1"8"7Ir to "2"1"3At have been analysed. This analysis has shown that shell effects in symmetric-mode fragment mass yields from the fission of pre-actinide nuclei could be described if one assumes the existence of two strongly deformed neutron shells in the arising fragments with neutron numbers N_1#approx#52 and N_2#approx#68. A new method has been proposed for quantitatively describing the mass distributions of the symmetric fission mode for pre-actinides with A#approx#180-220. (orig.)

1998-09-21

483

Qualitative risk assessment in the ANS LPSD PRA Standard  

Energy Technology Data Exchange (ETDEWEB)

This paper describes a Qualitative/Screening Methodology included in the draft ANS Low Power and Shutdown (LPSD) PRA (Probabilistic Risk Assessment) Standard. The screening methodology can be used to eliminate certain specified shutdown POSs (Plant Operating States) from requiring further quantitative risk assessment in the context of a specified application based on demonstrating that their risk is lower than some predetermined limiting value. The paper also describes a methodology for qualitative risk assessment (QRA) tools that are used to support the screening process. The paper outlines the bases of both methodologies. (authors)

2004-07-01

484

Phase diagram and effective shape of semi-flexible colloidal rods and biopolymers  

CERN Document Server

We study suspensions of semi-flexible colloidal rods and biopolymers using an Onsager-type second-virial functional for a segmented-chain model. For suspensions of thin and thick fd virus particles we calculate phase diagrams in quantitative agreement with experimental observations, and we find their effective state-point dependent shape to be much shorter and thicker than the actual shape. We also calculate the stretching of worm-like micelles in a host fd virus solution, again finding agreement with experiments. For both systems, our results show that the fd virus stiffness can play a key role in system behavior.

2011-01-01

485

Neutron activation analysis of trace elements in Japanese hormesis cosmetics  

International Nuclear Information System (INIS)

In Japan, cosmetics claiming hormesis effect are available through Internet. Although these cosmetics show the contents, they never mention the minor elements and radioactive sources. The existence of radioisotopes, however, was observed by measurements of the gamma-rays with a HPGe detector. In this study, in order to clarify the contents of trace elements, the hormesis cosmetics including radioactive sources were analyzed using INAA, PGAA and NAA with multiple gamma-ray detection (NAAMG). Nineteen elements were analyzed quantitatively in hormesis cosmetics by INAA, PGAA and NAAMG and 16 elements were detected qualitatively by SEM-EPMA. (author)

2008-12-01

486

Modeling of extended defects in silicon  

Energy Technology Data Exchange (ETDEWEB)

Transient Enhanced Diffusion (TED) is one of the biggest modeling challenges present in predicting scaled technologies. Damage from implantation of dopant ions changes the diffusivities of the dopants and precipitates to form complex extended defects. Developing a quantitative model for the extended defect behavior during short time, low temperature anneals is a key to explaining TED. This paper reviews some of the modeling developments over the last several years, and discusses some of the challenges that remain to be addressed. Two examples of models compared to experimental work are presented and discussed.

1997-11-01

487

Low Power and Shutdown Risk Assessment Benchmarking Study  

Science.gov (United States)

(B204)Probabilistic risk assessment (PRA) insights are now used by the United States Nuclear Regulatory Commission (USNRC) to confirm the level of safety for plant operations and to justify changes in nuclear power plant operating requirements, both on an exception basis and as changeds to a plant's licensing basis. This report examines qualitative and quantitative risk assessments during shutdown plant states, providing feedback to utilities in the use of qualitative models for outage risk management, and also providing input to the development of the American Nuclear Society (ANS) Low Power and Shutdown PRA Standard.

2002-12-15

488

Low Power and Shutdown Risk Assessment Benchmarking Study  

Energy Technology Data Exchange (ETDEWEB)

(B204)Probabilistic risk assessment (PRA) insights are now used by the United States Nuclear Regulatory Commission (USNRC) to confirm the level of safety for plant operations and to justify changes in nuclear power plant operating requirements, both on an exception basis and as changeds to a plant's licensing basis. This report examines qualitative and quantitative risk assessments during shutdown plant states, providing feedback to utilities in the use of qualitative models for outage risk management, and also providing input to the development of the American Nuclear Society (ANS) Low Power and Shutdown PRA Standard.

2002-12-15

489

Josephson effect mm-wave receivers  

International Nuclear Information System (INIS)

Josephson effect heterodyne mixers with external local oscillators are very promising low noise mm-wave receivers for applications such as radio astronomy. Experiments at 36 GHz have shown that both the noise and the conversion efficiency of mixers made using Nb point contacts are in quantitative agreement with values calculated from the resistively shunted junction (RSJ) model. Preliminary measurements at 140 GHz suggest that this agreement extends to higher frequencies. In this paper the theoretical limits to the sensitivity of such receivers are explored as a function of the signal frequency. (Auth.).

490

Interpolation theory and influence of boundary conditions on room air diffusion  

Energy Technology Data Exchange (ETDEWEB)

This paper analyses the errors caused by interpolation from existing cases for assessing indoor air flow, air quality and thermal comfort in an office. A sensitivity study is then provided to determine the influence of several boundary conditions on indoor air diffusion. The research is conducted numerically by using a low-Reynolds-number k-{epsilon} model. It can be concluded that the interpolation errors caused by the variations of solar radiation, window size, heat source location due to lighting, and the surface temperatures of interior walls are small and can be quantitatively determined. But it is difficult to estimate the errors introduced by the variations of furniture location and size. (author).

1991-01-01

491

Impact of different forestry strategies on the function 'carbon wells on the forest planting. Simulation and modelization at the parcel scale; Impact de differentes strategies sylvicoles sur la fonction 'puits de carbone' des peuplements forestiers. Modelisation et simulation a l'echelle de la parcelle  

Energy Technology Data Exchange (ETDEWEB)

In the framework of the carbon storage two forestry methods are analyzed by the author: the standing capitalization (slowing of the crops) and the spices substitution (slow growing species by fast growing species). The construction of a model taking into account the all stage of the carbon implication (biomass, soil, forest products) offers simulation and quantitative results on these methods. (A.L.B.)

2005-10-15

492

Image analysis of complex microstructures by texture analysis and correlation with properties by neural networks; Bildanalyse komplexer Werkstoffgefuege durch Texturanalyse und Korrelation mit den Eigenschaften durch neuronale Netze  

Energy Technology Data Exchange (ETDEWEB)

By characterising the microstructure, quantitative image analysis allows to draw conclusions on the mechanical properties of materials. On fine microstructures with low contrast, e.g. of hardened steels, texture analysis has to be applied for quantification. Feeding texture parameters according to Haralick into a trained neural network, a correlation between the microstructure and the hardness of the steels C45 and 100Cr6 can be achieved. (orig.)

2001-08-01

493

Hard X-ray phase imaging and tomography using a grating interferometer  

International Nuclear Information System (INIS)

An interferometric technique for hard X-rays is presented. It is based on two transmission gratings and a phase-stepping technique, and it provides separate radiographs of the phase and absorption profiles of bulk samples. Tomographic reconstruction yields quantitative three-dimensional maps of the X-ray refractive index and of the attenuation coefficient, with a spatial resolution down to a few microns. The method is mechanically robust, it requires little monochromaticity, and can be scaled up to large fields of view. These are important prerequisites for use with laboratory X-ray sources. Numerous applications ranging from wave front sensing to medical radiography are presently under investigation.

2007-07-01

494

Experimental research on X-ray spectrum emitted from hot laser-produced aluminium plasma  

International Nuclear Information System (INIS)

The hot uniform aluminium plasma was produced by irradiating thin aluminium dotted foil smoothly with the 9th 0.53 ?m laser on Shenguang II laser facility. The emitted spectrum was measured from the front and tangential direction of the target with two crystal spectrometers, and the quantitative spectrum from the front of the target was obtained. The state of laser- produced plasma was simulated with the radiation hydrodynamics code MULTI-1D, and the emitted spectrum was calculated with the spectrum code of Collision-Radiation model under the simulated plasma state. The experimental spectrum accords with the simulated one. (authors)

2007-12-01

495

Exact solution to NO/sub 2/ absorption  

Energy Technology Data Exchange (ETDEWEB)

This paper describes an exact solution to the problem of absorbing nitrogen dioxide into aqueous solution, in which case the nitrogen dioxide concentration is allowed to vary over a wide range. The authors have worked on the rate of calcium sulfate dihydrate scale formation on the reverse osmosis membrane and find this phenomena can be treated by the crystallization theory. The authors performed long-term experiments using calcium sulfate dihydrate solution with addition of sodium hexametaphosphate (SHMP) and commercially available organophosphates and investigated the mechanism of the inhibitor's action quantitatively.

1984-04-01

496

Displacement ventilation in industry - a design principle for improved air quality  

Energy Technology Data Exchange (ETDEWEB)

There is very little quantitative documentation of actual improvements resulting from the installation of new general ventilation systems in industrial settings. Therefore the performance of the common mixing design principle was compared to the displacement design principle by means of an intervention study in a workshop (V = 12,000 m[sup 3]), where thermoplastics were moulded. An experimental signal-response tracer gas technique was used. In terms of supplying fresh air to the zone of occupancy the displacement system was better than the mixing system by a factor of 2. In terms of the exposure level to a simulated contaminant (tracer gas) the displacement system was better by a factor 1.5-18. (author)

1992-10-01

497

Conceptual Assessment Framework for Forested Wetland Restoration: The Pen Branch Experience. Restoration of a Severely Impacted Riparian Wetland System - The Pen Branch Project  

Energy Technology Data Exchange (ETDEWEB)

Development of an assessment framework and indicators can be used to evaluate effectiveness of wetland restoration. Example of these include index of biotic integrity and the hydrogeomorphic method. Both approaches provide qualitative ranks. We propose a new method based on the EPA wetland research program. Similar to other methods, indexes are compared to reference communities; however, the comparisons are quantitative. In this paper we discuss the results of our framework using the Pen Branch riparian wetland system as an example.

2000-10-01

498

Comparison of Different Methods for Nonlinear Diffusive Shock Acceleration  

CERN Document Server

We provide a both qualitative and quantitative comparison among different approaches aimed to solve the problem of non-linear diffusive acceleration of particles at shocks. In particular, we show that state-of-the-art models (numerical, Monte Carlo and semi-analytical), even if based on different physical assumptions and implementations, for typical environmental parameters lead to very consistent results in terms of shock hydrodynamics, cosmic ray spectrum and also escaping flux spectrum and anisotropy. Strong points and limits of each approach are also discussed, as a function of the problem one wants to study.

2010-01-01

499

Application of light microscopy to direct coal liquefaction research  

Energy Technology Data Exchange (ETDEWEB)

Light microscopy was used to analyze the effects of added catalyst at different conditions (temperature and reaction times) in liquefaction testing of a low pyritic sulfur bituminous coal. Quantitative changes in vitrinite/vitroplast reflectance of coal and liquefaction residues were shown to be useful markers in analyzing and understanding the role of catalyst during the initial stage of coal particle hydrogenation. Lower reflectance values corresponded to increased conversions up to about the 60 min and 375{degrees}C experimental conditions. Microscopical observation of liquefaction residues also revealed the presence of `wall scales` of varying width.

1998-01-01

500

Analysis of the chemical transformations induced at the surface of polyacrylonitrile and polymethacrylonitrile films by 5 keV proton beams  

Energy Technology Data Exchange (ETDEWEB)

In this work, the chemical transformations induced by 5 keV protons (10{sup 6} ion cm{sup -2}) at the surface of 0.4 {mu}m polyacrylonitrile and polymethacrylonitrile films are analysed by XPS and IRRAS. Spectroscopic changes in both the polymers are globally similar, the most significant feature being a lower relative concentration of nitrogen with respect to carbon closer to the surface. Quantitatively, this change is more marked in the case of polyacrylonitrile which suggests a direct relation with the hydrogen in {alpha} to the nitrile function.

1999-05-02